Heat shock protein 90

Overview


Name	Heat shock protein 90
Smed ID	SMED30020317
Length (bp)	2308

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Heat shock protein 90 (SMED30020317) t-SNE clustered cells

Violin plots show distribution of expression levels for Heat shock protein 90 (SMED30020317) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Heat shock protein 90 (SMED30020317) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Heat shock protein 90 (SMED30020317) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30020317

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 19

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
gut	SMED30020317	h1SMcG0005587	Contig1490	GPL15192	PMID:23079596 Forsthoefel et al., 2012
dorsal ventral margin of the whole animal	SMED30020317	h1SMcG0005587	Contig1490	GPL15192	PMID:23079596 Forsthoefel et al., 2012
intestinal phagocyte	SMED30020317	h1SMcG0005587	Contig1490	GPL15192	PMID:23079596 Forsthoefel et al., 2012
nervous system	SMED30020317	h1SMcG0005587	dd_Smed_v4_678_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
gut	SMED30020317	h1SMcG0005587	dd_Smed_v4_678_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30020317	h1SMcG0005587	dd_Smed_v4_678_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30020317	h1SMcG0005587	dd_Smed_v4_678_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
muscle cell	SMED30020317	h1SMcG0005587	dd_Smed_v4_678_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30020317	h1SMcG0005587	dd_Smed_v4_678_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30020317	h1SMcG0005587	dd_Smed_v4_678_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30020317	h1SMcG0005587	Contig49305	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30020317	h1SMcG0005587	Contig49305	newmark_ests	PMID:29674431 Fincher et al., 2018
head region	SMED30020317	h1SMcG0005587	dd_Smed_v6_678_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
neuron	SMED30020317	h1SMcG0005587	Contig49305	uc_Smed_v2	PMID:27612384 Roberts-Galbraith et al., 2016
neuron	SMED30020317	h1SMcG0005587	Contig49305	newmark_ests	PMID:27612384 Roberts-Galbraith et al., 2016
Category 2 cell	SMED30020317	h1SMcG0005587	dd_Smed_v6_678_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
Category 3 cell	SMED30020317	h1SMcG0005587	dd_Smed_v6_678_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
progenitor cell	SMED30020317	h1SMcG0005587	dd_Smed_v6_678_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
parenchymal cell	SMED30020317	h1SMcG0005587	dd_Smed_v6_678_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of Heat shock protein 90 vs. Ensembl Human
Match: HSP90AA1 (heat shock protein 90 alpha family class A member 1 [Source:HGNC Symbol;Acc:HGNC:5253])

HSP 1 Score: 679.863 bits (1753), Expect = 0.000e+0
Identity = 350/445 (78.65%), Postives = 400/445 (89.89%), Query Frame = 3

Query:  852 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNLKLGIHEDSVNRNKLADFLRYHSTSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSVMKALKTRVDADKNDKSVKDLVMLLYETSLLSSGFALEDPQIHANRIHRMIKLGLGXXXXXXXXXXXXVG---DVPVGPSATEDEAGKMEEVD 2177
            LNKTKPIWTRNPDD++ E+Y EFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF P+RAPFDLFEN+KK+NNIKLYVRRVFIMDNCE+LIPEYLNF++GVVDSEDLPLNISREMLQQ+KILKVIRKNLVKKCLELF E+ EDK+NYKKFYEQF+KN+KLGIHEDS NR KL++ LRY++++SG+EM SLKDY +RMKENQK IYYITGE+KD VA+SAFVERL K G EV+YMI+PIDEY VQQLKE++GK LV VTKEGLELPEDEEEKKK EE+K  FE LCK+MKDIL+KKVEKV VSNRLV+SPCCIVTS +GW+ANMERIMKAQALRD+STMGYMAAKKHLEINPDHS+++ L+ + +ADKNDKSVKDLV+LLYET+LLSSGF+LEDPQ HANRI+RMIKLGLGIDEDD   D T      ++P  P   +D+  +MEEVD
Sbjct:  290 LNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMP--PLEGDDDTSRMEEVD 732

HSP 2 Score: 349.362 bits (895), Expect = 1.092e-108
Identity = 178/214 (83.18%), Postives = 198/214 (92.52%), Query Frame = 3

Query:   57 ETFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKGNDDEQYLWESSAGGSFTIKPDTSEPLGRGSKIILFMKEDQVEYLXXXXXXXXXXXHSQFIGYPIKLVLEKERDKEVS 698
            ETFAFQAEIAQL+SLIINTFYSNKEIFLRELISNSSDALDKIRY+SLTDPS LD+ KEL I +IP+K   TLTI+DTGIGMTK+DLINNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVA+KV VI+K NDDEQY WESSAGGSFT++ DT EP+GRG+K+IL +KEDQ EYLEER+IKEI+KKHSQFIGYPI L +EKERDKEVS
Sbjct:   18 ETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVS 231

[Close]

BLAST of Heat shock protein 90 vs. Ensembl Human
Match: HSP90AA1 (heat shock protein 90 alpha family class A member 1 [Source:HGNC Symbol;Acc:HGNC:5253])

HSP 1 Score: 677.552 bits (1747), Expect = 0.000e+0
Identity = 350/445 (78.65%), Postives = 400/445 (89.89%), Query Frame = 3

Query:  852 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNLKLGIHEDSVNRNKLADFLRYHSTSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSVMKALKTRVDADKNDKSVKDLVMLLYETSLLSSGFALEDPQIHANRIHRMIKLGLGXXXXXXXXXXXXVG---DVPVGPSATEDEAGKMEEVD 2177
            LNKTKPIWTRNPDD++ E+Y EFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF P+RAPFDLFEN+KK+NNIKLYVRRVFIMDNCE+LIPEYLNF++GVVDSEDLPLNISREMLQQ+KILKVIRKNLVKKCLELF E+ EDK+NYKKFYEQF+KN+KLGIHEDS NR KL++ LRY++++SG+EM SLKDY +RMKENQK IYYITGE+KD VA+SAFVERL K G EV+YMI+PIDEY VQQLKE++GK LV VTKEGLELPEDEEEKKK EE+K  FE LCK+MKDIL+KKVEKV VSNRLV+SPCCIVTS +GW+ANMERIMKAQALRD+STMGYMAAKKHLEINPDHS+++ L+ + +ADKNDKSVKDLV+LLYET+LLSSGF+LEDPQ HANRI+RMIKLGLGIDEDD   D T      ++P  P   +D+  +MEEVD
Sbjct:  412 LNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMP--PLEGDDDTSRMEEVD 854

HSP 2 Score: 347.821 bits (891), Expect = 6.926e-107
Identity = 178/214 (83.18%), Postives = 198/214 (92.52%), Query Frame = 3

Query:   57 ETFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKGNDDEQYLWESSAGGSFTIKPDTSEPLGRGSKIILFMKEDQVEYLXXXXXXXXXXXHSQFIGYPIKLVLEKERDKEVS 698
            ETFAFQAEIAQL+SLIINTFYSNKEIFLRELISNSSDALDKIRY+SLTDPS LD+ KEL I +IP+K   TLTI+DTGIGMTK+DLINNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVA+KV VI+K NDDEQY WESSAGGSFT++ DT EP+GRG+K+IL +KEDQ EYLEER+IKEI+KKHSQFIGYPI L +EKERDKEVS
Sbjct:  140 ETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVS 353

[Close]

BLAST of Heat shock protein 90 vs. Ensembl Human
Match: HSP90AB1 (heat shock protein 90 alpha family class B member 1 [Source:HGNC Symbol;Acc:HGNC:5258])

HSP 1 Score: 655.981 bits (1691), Expect = 0.000e+0
Identity = 344/444 (77.48%), Postives = 400/444 (90.09%), Query Frame = 3

Query:  852 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNLKLGIHEDSVNRNKLADFLRYHSTSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSVMKALKTRVDADKNDKSVKDLVMLLYETSLLSSGFALEDPQIHANRIHRMIKLGLGXXXXXXXXXXXXVGDVP--VGPSATEDEAGKMEEVD 2177
            LNKTKPIWTRNPDD++QE+Y EFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF P+RAPFDLFENKKK+NNIKLYVRRVFIMD+C++LIPEYLNF++GVVDSEDLPLNISREMLQQ+KILKVIRKN+VKKCLELF E+ EDK+NYKKFYE F+KNLKLGIHEDS NR +L++ LRYH++ SG+EMTSL +Y+SRMKE QK IYYITGESK+ VA+SAFVER+ KRGFEV+YM +PIDEY VQQLKE+DGK LV VTKEGLELPEDEEEKKK EE KA FE LCK+MK+ILDKKVEKVT+SNRLVSSPCCIVTS +GW+ANMERIMKAQALRD+STMGYM AKKHLEINPDH +++ L+ + +ADKNDK+VKDLV+LL+ET+LLSSGF+LEDPQ H+NRI+RMIKLGLGIDED++  +      VP  + P   +++A +MEEVD
Sbjct:  282 LNKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGDEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEGLELPEDEEEKKKMEESKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEADKNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNRIYRMIKLGLGIDEDEVAAEEPNAA-VPDEIPPLEGDEDASRMEEVD 724

HSP 2 Score: 339.732 bits (870), Expect = 4.198e-105
Identity = 171/213 (80.28%), Postives = 195/213 (91.55%), Query Frame = 3

Query:   60 TFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKGNDDEQYLWESSAGGSFTIKPDTSEPLGRGSKIILFMKEDQVEYLXXXXXXXXXXXHSQFIGYPIKLVLEKERDKEVS 698
            TFAFQAEIAQL+SLIINTFYSNKEIFLRELISN+SDALDKIRY+SLTDPS LD+ KEL I IIP+    TLT++DTGIGMTK+DLINNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVA+KV VI+K NDDEQY WESSAGGSFT++ D  EP+GRG+K+IL +KEDQ EYLEER++KE++KKHSQFIGYPI L LEKER+KE+S
Sbjct:   14 TFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHGEPIGRGTKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEIS 226

[Close]

Query:  852 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNLKLGIHEDSVNRNKLADFLRYHSTSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSVMKALKTRVDADKNDKSVKDLVMLLYETSLLSSGFALEDPQIHANRIHRMIKLGLGXXXXXXXXXXXXVGDVP--VGPSATEDEAGKMEEVD 2177
            LNKTKPIWTRNPDD++QE+Y EFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF P+RAPFDLFENKKK+NNIKLYVRRVFIMD+C++LIPEYLNF++GVVDSEDLPLNISREMLQQ+KILKVIRKN+VKKCLELF E+ EDK+NYKKFYE F+KNLKLGIHEDS NR +L++ LRYH++ SG+EMTSL +Y+SRMKE QK IYYITGESK+ VA+SAFVER+ KRGFEV+YM +PIDEY VQQLKE+DGK LV VTKEGLELPEDEEEKKK EE KA FE LCK+MK+ILDKKVEKVT+SNRLVSSPCCIVTS +GW+ANMERIMKAQALRD+STMGYM AKKHLEINPDH +++ L+ + +ADKNDK+VKDLV+LL+ET+LLSSGF+LEDPQ H+NRI+RMIKLGLGIDED++  +      VP  + P   +++A +MEEVD
Sbjct:  282 LNKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGDEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEGLELPEDEEEKKKMEESKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEADKNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNRIYRMIKLGLGIDEDEVAAEEPNAA-VPDEIPPLEGDEDASRMEEVD 724

HSP 2 Score: 339.732 bits (870), Expect = 4.198e-105
Identity = 171/213 (80.28%), Postives = 195/213 (91.55%), Query Frame = 3

Query:   60 TFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKGNDDEQYLWESSAGGSFTIKPDTSEPLGRGSKIILFMKEDQVEYLXXXXXXXXXXXHSQFIGYPIKLVLEKERDKEVS 698
            TFAFQAEIAQL+SLIINTFYSNKEIFLRELISN+SDALDKIRY+SLTDPS LD+ KEL I IIP+    TLT++DTGIGMTK+DLINNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVA+KV VI+K NDDEQY WESSAGGSFT++ D  EP+GRG+K+IL +KEDQ EYLEER++KE++KKHSQFIGYPI L LEKER+KE+S
Sbjct:   14 TFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHGEPIGRGTKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEIS 226

[Close]

Query:  852 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNLKLGIHEDSVNRNKLADFLRYHSTSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSVMKALKTRVDADKNDKSVKDLVMLLYETSLLSSGFALEDPQIHANRIHRMIKLGLGXXXXXXXXXXXXVGDVP--VGPSATEDEAGKMEEVD 2177
            LNKTKPIWTRNPDD++QE+Y EFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF P+RAPFDLFENKKK+NNIKLYVRRVFIMD+C++LIPEYLNF++GVVDSEDLPLNISREMLQQ+KILKVIRKN+VKKCLELF E+ EDK+NYKKFYE F+KNLKLGIHEDS NR +L++ LRYH++ SG+EMTSL +Y+SRMKE QK IYYITGESK+ VA+SAFVER+ KRGFEV+YM +PIDEY VQQLKE+DGK LV VTKEGLELPEDEEEKKK EE KA FE LCK+MK+ILDKKVEKVT+SNRLVSSPCCIVTS +GW+ANMERIMKAQALRD+STMGYM AKKHLEINPDH +++ L+ + +ADKNDK+VKDLV+LL+ET+LLSSGF+LEDPQ H+NRI+RMIKLGLGIDED++  +      VP  + P   +++A +MEEVD
Sbjct:  282 LNKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGDEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEGLELPEDEEEKKKMEESKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEADKNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNRIYRMIKLGLGIDEDEVAAEEPNAA-VPDEIPPLEGDEDASRMEEVD 724

HSP 2 Score: 339.732 bits (870), Expect = 4.198e-105
Identity = 171/213 (80.28%), Postives = 195/213 (91.55%), Query Frame = 3

Query:   60 TFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKGNDDEQYLWESSAGGSFTIKPDTSEPLGRGSKIILFMKEDQVEYLXXXXXXXXXXXHSQFIGYPIKLVLEKERDKEVS 698
            TFAFQAEIAQL+SLIINTFYSNKEIFLRELISN+SDALDKIRY+SLTDPS LD+ KEL I IIP+    TLT++DTGIGMTK+DLINNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVA+KV VI+K NDDEQY WESSAGGSFT++ D  EP+GRG+K+IL +KEDQ EYLEER++KE++KKHSQFIGYPI L LEKER+KE+S
Sbjct:   14 TFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHGEPIGRGTKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEIS 226

[Close]

BLAST of Heat shock protein 90 vs. Ensembl Celegans
Match: hsp-90 (Heat shock protein 90 [Source:UniProtKB/Swiss-Prot;Acc:Q18688])

HSP 1 Score: 675.241 bits (1741), Expect = 0.000e+0
Identity = 352/455 (77.36%), Postives = 396/455 (87.03%), Query Frame = 3

Query:  852 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNLKLGIHEDSVNRNKLADFLRYHSTSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSVMKALKTRVDADKNDKSVKDLVMLLYETSLLSSGFALEDPQIHANRIHRMIKLGLGXXXXXXXXXXXXVGD-------VPVGPSA------TEDEAGKMEEVD 2177
            LNKTKPIWTRNPDD+S E+YAEFYKSL+NDWEDHLAVKHFSVEGQLEFRALLF P+RAPFDLFENKK +N+IKLYVRRVFIM+NCE+L+PEYLNF+KGVVDSEDLPLNISREMLQQ+KILKVIRKNLVKKC+EL +E+ EDKDN+KKFYEQF KNLKLGIHEDS NR KL+DFLRY STS+G+E TSLK+Y+SRMKENQ  IYYITGESKD VA SAFVER+  RGFEVLYM DPIDEY VQQLKEYDGKKLV VTKEGLELPE EEEKKKFEE K A+E LCKV+KDIL+KKVEKV VSNRLVSSPCCIVTS++GWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDH++MK L+ RV+ DKNDK+VKDLV+LL+ET+LL+SGF+LE+PQ HA+RI+RMIKLGL             +GD       VP   +A       E++A +MEEVD
Sbjct:  261 LNKTKPIWTRNPDDISNEEYAEFYKSLSNDWEDHLAVKHFSVEGQLEFRALLFVPQRAPFDLFENKKSKNSIKLYVRRVFIMENCEELMPEYLNFIKGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCMELIDEVAEDKDNFKKFYEQFGKNLKLGIHEDSTNRKKLSDFLRY-STSAGDEPTSLKEYVSRMKENQTQIYYITGESKDVVAASAFVERVKSRGFEVLYMCDPIDEYCVQQLKEYDGKKLVSVTKEGLELPETEEEKKKFEEDKVAYENLCKVIKDILEKKVEKVGVSNRLVSSPCCIVTSEYGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHAIMKTLRDRVEVDKNDKTVKDLVVLLFETALLASGFSLEEPQSHASRIYRMIKLGLD------------IGDDEIEDSAVPSSCTAEAKIEGAEEDASRMEEVD 702

HSP 2 Score: 312.768 bits (800), Expect = 1.483e-95
Identity = 158/205 (77.07%), Postives = 186/205 (90.73%), Query Frame = 3

Query:   51 DSETFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKGNDDEQYLWESSAGGSFTIKPDTSEPLGRGSKIILFMKEDQVEYLXXXXXXXXXXXHSQFIGYPIKL 665
            ++ETFAFQAEIAQL+SLIINTFYSNKEI+LRELISN+SDALDKIRY++LT+PS LDT KEL IKI P+K+  TLTI+DTGIGMTK+DL+NNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS++LVADKV V SK NDD+ Y WESSAGGSF ++P     + RG+KI++ +KEDQ+++LEERKIKEI+KKHSQFIGYPIKL
Sbjct:    4 NAETFAFQAEIAQLMSLIINTFYSNKEIYLRELISNASDALDKIRYQALTEPSELDTGKELFIKITPNKEEKTLTIMDTGIGMTKADLVNNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAFLVADKVVVTSKNNDDDSYQWESSAGGSFVVRPFNDPEVTRGTKIVMHIKEDQIDFLEERKIKEIVKKHSQFIGYPIKL 208

[Close]

Query:  852 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNLKLGIHEDSVNRNKLADFLRYHSTSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSVMKALKTRVDADKNDKSVKDLVMLLYETSLLSSGFALEDPQIHANRIHRMIKLGLGXXXXXXXXXXXXVGD-------VPVGPSA------TEDEAGKMEEVD 2177
            LNKTKPIWTRNPDD+S E+YAEFYKSL+NDWEDHLAVKHFSVEGQLEFRALLF P+RAPFDLFENKK +N+IKLYVRRVFIM+NCE+L+PEYLNF+KGVVDSEDLPLNISREMLQQ+KILKVIRKNLVKKC+EL +E+ EDKDN+KKFYEQF KNLKLGIHEDS NR KL+DFLRY STS+G+E TSLK+Y+SRMKENQ  IYYITGESKD VA SAFVER+  RGFEVLYM DPIDEY VQQLKEYDGKKLV VTKEGLELPE EEEKKKFEE K A+E LCKV+KDIL+KKVEKV VSNRLVSSPCCIVTS++GWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDH++MK L+ RV+ DKNDK+VKDLV+LL+ET+LL+SGF+LE+PQ HA+RI+RMIKLGL             +GD       VP   +A       E++A +MEEVD
Sbjct:  261 LNKTKPIWTRNPDDISNEEYAEFYKSLSNDWEDHLAVKHFSVEGQLEFRALLFVPQRAPFDLFENKKSKNSIKLYVRRVFIMENCEELMPEYLNFIKGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCMELIDEVAEDKDNFKKFYEQFGKNLKLGIHEDSTNRKKLSDFLRY-STSAGDEPTSLKEYVSRMKENQTQIYYITGESKDVVAASAFVERVKSRGFEVLYMCDPIDEYCVQQLKEYDGKKLVSVTKEGLELPETEEEKKKFEEDKVAYENLCKVIKDILEKKVEKVGVSNRLVSSPCCIVTSEYGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHAIMKTLRDRVEVDKNDKTVKDLVVLLFETALLASGFSLEEPQSHASRIYRMIKLGLD------------IGDDEIEDSAVPSSCTAEAKIEGAEEDASRMEEVD 702

HSP 2 Score: 312.768 bits (800), Expect = 1.483e-95
Identity = 158/205 (77.07%), Postives = 186/205 (90.73%), Query Frame = 3

Query:   51 DSETFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKGNDDEQYLWESSAGGSFTIKPDTSEPLGRGSKIILFMKEDQVEYLXXXXXXXXXXXHSQFIGYPIKL 665
            ++ETFAFQAEIAQL+SLIINTFYSNKEI+LRELISN+SDALDKIRY++LT+PS LDT KEL IKI P+K+  TLTI+DTGIGMTK+DL+NNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS++LVADKV V SK NDD+ Y WESSAGGSF ++P     + RG+KI++ +KEDQ+++LEERKIKEI+KKHSQFIGYPIKL
Sbjct:    4 NAETFAFQAEIAQLMSLIINTFYSNKEIYLRELISNASDALDKIRYQALTEPSELDTGKELFIKITPNKEEKTLTIMDTGIGMTKADLVNNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAFLVADKVVVTSKNNDDDSYQWESSAGGSFVVRPFNDPEVTRGTKIVMHIKEDQIDFLEERKIKEIVKKHSQFIGYPIKL 208

[Close]

Query:  852 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNLKLGIHEDSVNRNKLADFLRYHSTSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSVMKALKTRVDADKNDKSVKDLVMLLYETSLLSSGFALEDPQIHANRIHRMIKLGLGXXXXXXXXXXXXVGD-------VPVGPSA------TEDEAGKMEEVD 2177
            LNKTKPIWTRNPDD+S E+YAEFYKSL+NDWEDHLAVKHFSVEGQLEFRALLF P+RAPFDLFENKK +N+IKLYVRRVFIM+NCE+L+PEYLNF+KGVVDSEDLPLNISREMLQQ+KILKVIRKNLVKKC+EL +E+ EDKDN+KKFYEQF KNLKLGIHEDS NR KL+DFLRY STS+G+E TSLK+Y+SRMKENQ  IYYITGESKD VA SAFVER+  RGFEVLYM DPIDEY VQQLKEYDGKKLV VTKEGLELPE EEEKKKFEE K A+E LCKV+KDIL+KKVEKV VSNRLVSSPCCIVTS++GWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDH++MK L+ RV+ DKNDK+VKDLV+LL+ET+LL+SGF+LE+PQ HA+RI+RMIKLGL             +GD       VP   +A       E++A +MEEVD
Sbjct:  261 LNKTKPIWTRNPDDISNEEYAEFYKSLSNDWEDHLAVKHFSVEGQLEFRALLFVPQRAPFDLFENKKSKNSIKLYVRRVFIMENCEELMPEYLNFIKGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCMELIDEVAEDKDNFKKFYEQFGKNLKLGIHEDSTNRKKLSDFLRY-STSAGDEPTSLKEYVSRMKENQTQIYYITGESKDVVAASAFVERVKSRGFEVLYMCDPIDEYCVQQLKEYDGKKLVSVTKEGLELPETEEEKKKFEEDKVAYENLCKVIKDILEKKVEKVGVSNRLVSSPCCIVTSEYGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHAIMKTLRDRVEVDKNDKTVKDLVVLLFETALLASGFSLEEPQSHASRIYRMIKLGLD------------IGDDEIEDSAVPSSCTAEAKIEGAEEDASRMEEVD 702

HSP 2 Score: 312.768 bits (800), Expect = 1.483e-95
Identity = 158/205 (77.07%), Postives = 186/205 (90.73%), Query Frame = 3

Query:   51 DSETFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKGNDDEQYLWESSAGGSFTIKPDTSEPLGRGSKIILFMKEDQVEYLXXXXXXXXXXXHSQFIGYPIKL 665
            ++ETFAFQAEIAQL+SLIINTFYSNKEI+LRELISN+SDALDKIRY++LT+PS LDT KEL IKI P+K+  TLTI+DTGIGMTK+DL+NNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS++LVADKV V SK NDD+ Y WESSAGGSF ++P     + RG+KI++ +KEDQ+++LEERKIKEI+KKHSQFIGYPIKL
Sbjct:    4 NAETFAFQAEIAQLMSLIINTFYSNKEIYLRELISNASDALDKIRYQALTEPSELDTGKELFIKITPNKEEKTLTIMDTGIGMTKADLVNNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAFLVADKVVVTSKNNDDDSYQWESSAGGSFVVRPFNDPEVTRGTKIVMHIKEDQIDFLEERKIKEIVKKHSQFIGYPIKL 208

[Close]

Query:  852 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNLKLGIHEDSVNRNKLADFLRYHSTSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSVMKALKTRVDADKNDKSVKDLVMLLYETSLLSSGFALEDPQIHANRIHRMIKLGLGXXXXXXXXXXXXVGD-------VPVGPSA------TEDEAGKMEEVD 2177
            LNKTKPIWTRNPDD+S E+YAEFYKSL+NDWEDHLAVKHFSVEGQLEFRALLF P+RAPFDLFENKK +N+IKLYVRRVFIM+NCE+L+PEYLNF+KGVVDSEDLPLNISREMLQQ+KILKVIRKNLVKKC+EL +E+ EDKDN+KKFYEQF KNLKLGIHEDS NR KL+DFLRY STS+G+E TSLK+Y+SRMKENQ  IYYITGESKD VA SAFVER+  RGFEVLYM DPIDEY VQQLKEYDGKKLV VTKEGLELPE EEEKKKFEE K A+E LCKV+KDIL+KKVEKV VSNRLVSSPCCIVTS++GWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDH++MK L+ RV+ DKNDK+VKDLV+LL+ET+LL+SGF+LE+PQ HA+RI+RMIKLGL             +GD       VP   +A       E++A +MEEVD
Sbjct:  261 LNKTKPIWTRNPDDISNEEYAEFYKSLSNDWEDHLAVKHFSVEGQLEFRALLFVPQRAPFDLFENKKSKNSIKLYVRRVFIMENCEELMPEYLNFIKGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCMELIDEVAEDKDNFKKFYEQFGKNLKLGIHEDSTNRKKLSDFLRY-STSAGDEPTSLKEYVSRMKENQTQIYYITGESKDVVAASAFVERVKSRGFEVLYMCDPIDEYCVQQLKEYDGKKLVSVTKEGLELPETEEEKKKFEEDKVAYENLCKVIKDILEKKVEKVGVSNRLVSSPCCIVTSEYGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHAIMKTLRDRVEVDKNDKTVKDLVVLLFETALLASGFSLEEPQSHASRIYRMIKLGLD------------IGDDEIEDSAVPSSCTAEAKIEGAEEDASRMEEVD 702

HSP 2 Score: 312.768 bits (800), Expect = 1.483e-95
Identity = 158/205 (77.07%), Postives = 186/205 (90.73%), Query Frame = 3

Query:   51 DSETFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKGNDDEQYLWESSAGGSFTIKPDTSEPLGRGSKIILFMKEDQVEYLXXXXXXXXXXXHSQFIGYPIKL 665
            ++ETFAFQAEIAQL+SLIINTFYSNKEI+LRELISN+SDALDKIRY++LT+PS LDT KEL IKI P+K+  TLTI+DTGIGMTK+DL+NNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS++LVADKV V SK NDD+ Y WESSAGGSF ++P     + RG+KI++ +KEDQ+++LEERKIKEI+KKHSQFIGYPIKL
Sbjct:    4 NAETFAFQAEIAQLMSLIINTFYSNKEIYLRELISNASDALDKIRYQALTEPSELDTGKELFIKITPNKEEKTLTIMDTGIGMTKADLVNNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAFLVADKVVVTSKNNDDDSYQWESSAGGSFVVRPFNDPEVTRGTKIVMHIKEDQIDFLEERKIKEIVKKHSQFIGYPIKL 208

[Close]

BLAST of Heat shock protein 90 vs. Ensembl Celegans
Match: enpl-1 (Endoplasmin homolog [Source:UniProtKB/Swiss-Prot;Acc:Q22235])

HSP 1 Score: 335.88 bits (860), Expect = 1.729e-104
Identity = 186/412 (45.15%), Postives = 275/412 (66.75%), Query Frame = 3

Query:  852 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKR-NNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNLKLGIHEDSVNRNKLADFLRYHSTSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDI-LDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQAL---RDSSTMGYMAAKKHLEINPDHSVMKALKTRVDADKNDKSVKDLVMLLYETSLLSSGFALEDPQIHANRIHRMIKLGL 2072
            +N  KPIW R P+ V +++Y +FYKS+T D E+ L+  HFS EG++ FR++L+ PK++P D+F+N  K   NIKLYVRRVFI D+  D++P+YL+F++G+VDS+DLPLN+SRE LQQ+K+LKVI+K LV+K L++ +++  D   +  F+ +F+ N+KLG+ ED  NR +LA  LR+ S++  ++ T+L  Y+ RMKE Q  IYY+ G S+  V  S FVERL  +G+EVL++ + +DEY +Q + EY+ KK   V KEG+ + + E+ K+  +  +  F+PL   +K+  L   +EK  VS RLV SP  +V S +GWS NMERIMK+QA    +D +   Y   KK  EINP H V+K L  RV A + D +      LL+ET+ L SGF+L+D    A+RI  +++  L
Sbjct:  243 VNNVKPIWMRKPNQVEEDEYKQFYKSITKDSEEPLSHVHFSAEGEVSFRSILYVPKKSPNDMFQNYGKVIENIKLYVRRVFITDDFADMLPKYLSFIRGIVDSDDLPLNVSRENLQQHKLLKVIKKKLVRKVLDMLKKL--DGAQFDDFWSEFSTNIKLGVMEDPSNRMRLAKLLRFQSSNDADKTTTLAAYVERMKEKQDAIYYMAGTSRKEVETSPFVERLIAKGYEVLFLTEAVDEYCIQAMPEYESKKFQNVAKEGVTIDDGEKAKEAHKGLEEEFKPLTDWLKETALKDLIEKAVVSQRLVKSPSALVASSYGWSGNMERIMKSQAYAKAKDPTQDFYATQKKTFEINPRHPVIKELLKRVTASEEDTTAASTAKLLFETATLRSGFSLQDQVGFADRIEAVLRQSL 652

HSP 2 Score: 196.823 bits (499), Expect = 2.563e-53
Identity = 107/198 (54.04%), Postives = 140/198 (70.71%), Query Frame = 3

Query:   90 LLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFMEALQAGADIS-----MIGQFGVGFYSSYLVADKVQVISKGNDDEQYLWESSAGGSFTIKPDT-SEPLGRGSKIILFMKEDQVEYLXXXXXXXXXXXHSQFIGYPIKL 665
            ++ LIIN+ Y NKEIFLRELISN+SDALDKIR  SLTDP  L   +E+ +KI  D++   L I DTG+GMT+ DLINNLGTIARSGT  F+  L   A  S     +IGQFGVGFY+++LVAD+V V +K NDD+QY+WES +  SFTI  D     L RG++I L++KE+  ++LE   +K ++ K+SQFI + I L
Sbjct:    1 MMKLIINSLYRNKEIFLRELISNASDALDKIRLLSLTDPEQLRETEEMSVKIKADRENRLLHITDTGVGMTRQDLINNLGTIARSGTSEFLSKLMDTATSSDQQQDLIGQFGVGFYAAFLVADRVVVTTKNNDDDQYIWESDS-ASFTISKDPRGNTLKRGTQITLYLKEEAADFLEPDTLKNLVHKYSQFINFDIFL 197

[Close]

BLAST of Heat shock protein 90 vs. Ensembl Fly
Match: Hsp83 (gene:FBgn0001233 transcript:FBtr0332873)

HSP 1 Score: 987.638 bits (2552), Expect = 0.000e+0
Identity = 542/715 (75.80%), Postives = 620/715 (86.71%), Query Frame = 3

Query:   51 DSETFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKGNDDEQYLWESSAGGSFTIKPDTSEPLGRGSKIILFMKEDQVEYLXXXXXXXXXXXHSQFIGYPIKLVL----EKERDKEVSDDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNLKLGIHEDSVNRNKLADFLRYHSTSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSVMKALKTRVDADKNDKSVKDLVMLLYETSLLSSGFALEDPQIHANRIHRMIKLGLGXXXXXXXXX--XXXVGDVPVGPSATEDEAGKMEEVD 2177
            ++ETFAFQAEIAQL+SLIINTFYSNKEIFLRELISN+SDALDKIRY+SLTDPS LD+ KEL IK+IP+K AGTLTIIDTGIGMTKSDL+NNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVADKV V SK NDDEQY+WESSAGGSFT++ D SEPLGRG+KI+L++KEDQ +YLEE KIKEI+ KHSQFIGYPIKL++    EKE   + +DDE +   +K+E E  E K +    D++ D   KD KKKK IKEKY ++EELNKTKPIWTRNPDD+SQE+Y EFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF P+R PFDLFEN+KKRNNIKLYVRRVFIMDNCEDLIPEYLNF+KGVVDSEDLPLNISREMLQQNK+LKVIRKNLVKK +EL EE+ EDK+NYKKFY+QF+KNLKLG+HEDS NR KLADFLR+H+++SG++  SL DY+SRMK+NQK +Y+ITGESKD V++SAFVER+  RGFEV+YM +PIDEY +Q LKEY GK+LV VTKEGLELPEDE EKKK EE KA FE LCK+MK ILD KVEKV VSNRLV SPCCIVTSQFGWSANMERIMKAQALRD++TMGYMA KK LEINPDH +++ L+ + DADKNDK+VKDLV+LL+ETSLLSSGF+L+ PQ+HA+RI+RMIKLGLGIDED+          GD P     TED A  MEEVD
Sbjct:    4 EAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELYIKLIPNKTAGTLTIIDTGIGMTKSDLVNNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVADKVTVTSKNNDDEQYVWESSAGGSFTVRADNSEPLGRGTKIVLYIKEDQTDYLEESKIKEIVNKHSQFIGYPIKLLVEKEREKEVSDDEADDEKKEGDEKKEMETDEPKIEDVGEDEDADKKDKDAKKKKTIKEKYTEDEELNKTKPIWTRNPDDISQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRTPFDLFENQKKRNNIKLYVRRVFIMDNCEDLIPEYLNFMKGVVDSEDLPLNISREMLQQNKVLKVIRKNLVKKTMELIEELTEDKENYKKFYDQFSKNLKLGVHEDSNNRAKLADFLRFHTSASGDDFCSLADYVSRMKDNQKHVYFITGESKDQVSNSAFVERVKARGFEVVYMTEPIDEYVIQHLKEYKGKQLVSVTKEGLELPEDESEKKKREEDKAKFESLCKLMKSILDNKVEKVVVSNRLVDSPCCIVTSQFGWSANMERIMKAQALRDTATMGYMAGKKQLEINPDHPIVETLRQKADADKNDKAVKDLVILLFETSLLSSGFSLDSPQVHASRIYRMIKLGLGIDEDEPMTTDDAQSAGDAPSLVEDTED-ASHMEEVD 717

[Close]

BLAST of Heat shock protein 90 vs. Ensembl Fly
Match: Hsp83 (gene:FBgn0001233 transcript:FBtr0073040)

HSP 1 Score: 987.638 bits (2552), Expect = 0.000e+0
Identity = 542/715 (75.80%), Postives = 620/715 (86.71%), Query Frame = 3

Query:   51 DSETFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKGNDDEQYLWESSAGGSFTIKPDTSEPLGRGSKIILFMKEDQVEYLXXXXXXXXXXXHSQFIGYPIKLVL----EKERDKEVSDDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNLKLGIHEDSVNRNKLADFLRYHSTSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSVMKALKTRVDADKNDKSVKDLVMLLYETSLLSSGFALEDPQIHANRIHRMIKLGLGXXXXXXXXX--XXXVGDVPVGPSATEDEAGKMEEVD 2177
            ++ETFAFQAEIAQL+SLIINTFYSNKEIFLRELISN+SDALDKIRY+SLTDPS LD+ KEL IK+IP+K AGTLTIIDTGIGMTKSDL+NNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVADKV V SK NDDEQY+WESSAGGSFT++ D SEPLGRG+KI+L++KEDQ +YLEE KIKEI+ KHSQFIGYPIKL++    EKE   + +DDE +   +K+E E  E K +    D++ D   KD KKKK IKEKY ++EELNKTKPIWTRNPDD+SQE+Y EFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF P+R PFDLFEN+KKRNNIKLYVRRVFIMDNCEDLIPEYLNF+KGVVDSEDLPLNISREMLQQNK+LKVIRKNLVKK +EL EE+ EDK+NYKKFY+QF+KNLKLG+HEDS NR KLADFLR+H+++SG++  SL DY+SRMK+NQK +Y+ITGESKD V++SAFVER+  RGFEV+YM +PIDEY +Q LKEY GK+LV VTKEGLELPEDE EKKK EE KA FE LCK+MK ILD KVEKV VSNRLV SPCCIVTSQFGWSANMERIMKAQALRD++TMGYMA KK LEINPDH +++ L+ + DADKNDK+VKDLV+LL+ETSLLSSGF+L+ PQ+HA+RI+RMIKLGLGIDED+          GD P     TED A  MEEVD
Sbjct:    4 EAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELYIKLIPNKTAGTLTIIDTGIGMTKSDLVNNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVADKVTVTSKNNDDEQYVWESSAGGSFTVRADNSEPLGRGTKIVLYIKEDQTDYLEESKIKEIVNKHSQFIGYPIKLLVEKEREKEVSDDEADDEKKEGDEKKEMETDEPKIEDVGEDEDADKKDKDAKKKKTIKEKYTEDEELNKTKPIWTRNPDDISQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRTPFDLFENQKKRNNIKLYVRRVFIMDNCEDLIPEYLNFMKGVVDSEDLPLNISREMLQQNKVLKVIRKNLVKKTMELIEELTEDKENYKKFYDQFSKNLKLGVHEDSNNRAKLADFLRFHTSASGDDFCSLADYVSRMKDNQKHVYFITGESKDQVSNSAFVERVKARGFEVVYMTEPIDEYVIQHLKEYKGKQLVSVTKEGLELPEDESEKKKREEDKAKFESLCKLMKSILDNKVEKVVVSNRLVDSPCCIVTSQFGWSANMERIMKAQALRDTATMGYMAGKKQLEINPDHPIVETLRQKADADKNDKAVKDLVILLFETSLLSSGFSLDSPQVHASRIYRMIKLGLGIDEDEPMTTDDAQSAGDAPSLVEDTED-ASHMEEVD 717

[Close]

BLAST of Heat shock protein 90 vs. Ensembl Fly
Match: Gp93 (gene:FBgn0039562 transcript:FBtr0085254)

HSP 1 Score: 340.887 bits (873), Expect = 3.999e-105
Identity = 193/413 (46.73%), Postives = 282/413 (68.28%), Query Frame = 3

Query:  852 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFEN-KKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNLKLGIHEDSVNRNKLADFLRYHSTSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDI-LDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALR---DSSTMGYMAAKKHLEINPDHSVMKALKTRVDADKNDKSVKDLVMLLYETSLLSSGFALEDPQIHANRIHRMIKLGLG 2075
            +N +KPIWTR P +V++++Y  FYKSLT D  + L   HF  EG++ F++LL+ PK  P + F     K +NIKLYVRRVFI D   D++P YL+F++GVVDS+DLPLN+SRE LQQ+K++KVI+K LV+K L++ ++I  DK+ Y+KF+++F+ N+KLG+ ED  NR++LA  LR+  TS+G+ +TSL +Y  RMK  Q+ IYYI G ++  V  S FVERL  +G+EVLY+++ +DEY +  L E+DGKK   V KEG +L E E+ KK FE  K+ FEPL K + D+ L  ++ K  VS RL +SPC +V   FGW+ NMER+  + A +   D     Y+  KK LEINP H +M+ L  RV+AD+ D + KD+ ++++ T+ L SG+ L++    A+ I +M++  LG
Sbjct:  336 INDSKPIWTRKPAEVTEDEYTSFYKSLTKDSSEPLTQTHFIAEGEVTFKSLLYVPKVQPSESFNRYGTKSDNIKLYVRRVFITDEFNDMMPNYLSFIRGVVDSDDLPLNVSRETLQQHKLIKVIKKKLVRKVLDMLKKI--DKEAYEKFWKEFSTNIKLGVMEDPSNRSRLAKLLRFQ-TSNGKGVTSLAEYKERMKAKQEHIYYIAGANRAEVEKSPFVERLLSKGYEVLYLVEAVDEYCISALPEFDGKKFQNVAKEGFQLNESEKSKKNFESLKSTFEPLVKWLNDVALKDQISKAQVSERLSNSPCALVAGVFGWTGNMERLAMSNAHQKSDDPQRTYYLNQKKTLEINPRHPLMRELLRRVEADEADDTAKDMAVMMFRTATLRSGYMLQETSQFADSIEQMMRQTLG 745

HSP 2 Score: 205.297 bits (521), Expect = 1.219e-55
Identity = 115/218 (52.75%), Postives = 158/218 (72.48%), Query Frame = 3

Query:   33 LMESMNDSETFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFMEALQ-----AGADIS-MIGQFGVGFYSSYLVADKVQVISKGNDDEQYLWESSAGGSFTIKPDT-SEPLGRGSKIILFMKEDQVEYLXXXXXXXXXXXHSQFIGYPIKL 665
            L E    ++ F FQ E+ +++ LIIN+ Y NKEIFLRELISN+SDA+DKIR  +L++   L+T  EL I+I  DK+   L I+D+GIGMT  DLINNLGTIA+SGT  F+  +Q      G D++ MIGQFGVGFYS++LVAD+V V +K NDD+QY+WES A  SF+I  D   + L RGS I L++KE+  ++LEE  ++E+I+K+SQFI +PI++
Sbjct:   65 LKEIREKAKKFTFQTEVNRMMKLIINSLYRNKEIFLRELISNASDAIDKIRLLALSNSKELETNPELHIRIKADKENKALHIMDSGIGMTHQDLINNLGTIAKSGTADFLAKMQDPSKSEGLDMNDMIGQFGVGFYSAFLVADRVVVTTKHNDDKQYIWESDA-NSFSITEDPRGDTLKRGSVISLYLKEEAQDFLEEDTVRELIRKYSQFINFPIRM 281

[Close]

BLAST of Heat shock protein 90 vs. Ensembl Fly
Match: Trap1 (gene:FBgn0026761 transcript:FBtr0086149)

HSP 1 Score: 176.407 bits (446), Expect = 3.575e-46
Identity = 123/421 (29.22%), Postives = 217/421 (51.54%), Query Frame = 3

Query:  855 NKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNN-IKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDK-DNYKKFYEQFAKNLKLGI--HEDSVNRNKLADFLRYHS----TSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXX---XXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSVMKALKTRVDADKNDKSVKDLVML----LYETSLLSSGFALEDPQIHANRIHRMIKLGL 2072
            N+ KP+W   P  +S+E + +FY+ ++N ++      H++ +  L   ALL+ P+  P  LFE  +  N  + LY R+V I    E L+P++L FVKGVVDSED+PLN+SRE+LQ + +++ +   +  + +   +E  + + + Y+ FY  +   LK GI    D+  + ++A  LR+ S    T+SG    SL++Y + +   Q++IYY+   ++     S + E L KR   VL+  +P DE  + QL ++  KKLV V KE  E  ++        +    ++  + L   +++ L  +V KV  + RL + PC I   +    A     ++ Q+ +      +   +  LEINP H ++K L    ++D      KDL  L    L+  +++ +G A EDP++    ++ ++   L
Sbjct:  281 NEIKPLWLLEPQSISKEQHHDFYRFISNSFDVPRFTLHYNADVPLSIHALLYFPEGKP-GLFEMSRDGNTGVALYTRKVLIQSKTEHLLPKWLRFVKGVVDSEDIPLNLSRELLQNSSLIRKLSSVISTRVIRFLQERSKKQPEEYEAFYRDYGLFLKEGIVTSSDASEKEEIAKLLRFESSKSETASGR--MSLEEYYNAVPAEQQNIYYLAAPNRVLAESSPYYESLKKRNELVLFCYEPYDELVLMQLGKFKSKKLVSVEKEMREESKETTATTDFGEGSLLRSELDTLIPWLEEELRGQVIKVKATTRLDTHPCVITVEEM---AAARHFIRTQSHQVPEQNRFALLQPELEINPKHPIIKKLNKLRESD------KDLAQLIAKQLFANAMVGAGLA-EDPRMLLTNMNTLLSRAL 688

HSP 2 Score: 155.992 bits (393), Expect = 2.427e-39
Identity = 97/212 (45.75%), Postives = 138/212 (65.09%), Query Frame = 3

Query:   69 FQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLT--DPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFMEAL---QAG----ADISMIGQFGVGFYSSYLVADKVQVISKGN--DDEQYLWESSAGGSFTIK--PDTSEPLGRGSKIILFMKEDQVEYLXXXXXXXXXXXHSQFIGYPIKL 665
            FQAE  QLL ++  + YS+ E+F+RELISN+SDAL+K RY SL+    ++    + L I+I  DK    L I DTGIGMTK +L++NLGTIARSG+K F+E +   Q G    A  ++IGQFGVGFYSS++VA+KV+V ++    +     W +   G++ I+  PD       G++I+L +K D  EY +E +IK +IKK+S F+G PI L
Sbjct:   68 FQAETRQLLDIVARSLYSDHEVFVRELISNASDALEKFRYTSLSAGGENLAGKDRPLEIRITTDKPLMQLIIQDTGIGMTKEELVSNLGTIARSGSKKFLEQMKGTQQGASSEASSNIIGQFGVGFYSSFIVANKVEVFTRAAVPNAPGLRWSTDGSGTYEIEEVPDVE----LGTRIVLHLKTDCREYADEERIKAVIKKYSNFVGSPILL 275

[Close]

BLAST of Heat shock protein 90 vs. Ensembl Fly
Match: Trap1 (gene:FBgn0026761 transcript:FBtr0336666)

HSP 1 Score: 176.407 bits (446), Expect = 3.575e-46
Identity = 123/421 (29.22%), Postives = 217/421 (51.54%), Query Frame = 3

Query:  855 NKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNN-IKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDK-DNYKKFYEQFAKNLKLGI--HEDSVNRNKLADFLRYHS----TSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXX---XXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSVMKALKTRVDADKNDKSVKDLVML----LYETSLLSSGFALEDPQIHANRIHRMIKLGL 2072
            N+ KP+W   P  +S+E + +FY+ ++N ++      H++ +  L   ALL+ P+  P  LFE  +  N  + LY R+V I    E L+P++L FVKGVVDSED+PLN+SRE+LQ + +++ +   +  + +   +E  + + + Y+ FY  +   LK GI    D+  + ++A  LR+ S    T+SG    SL++Y + +   Q++IYY+   ++     S + E L KR   VL+  +P DE  + QL ++  KKLV V KE  E  ++        +    ++  + L   +++ L  +V KV  + RL + PC I   +    A     ++ Q+ +      +   +  LEINP H ++K L    ++D      KDL  L    L+  +++ +G A EDP++    ++ ++   L
Sbjct:  281 NEIKPLWLLEPQSISKEQHHDFYRFISNSFDVPRFTLHYNADVPLSIHALLYFPEGKP-GLFEMSRDGNTGVALYTRKVLIQSKTEHLLPKWLRFVKGVVDSEDIPLNLSRELLQNSSLIRKLSSVISTRVIRFLQERSKKQPEEYEAFYRDYGLFLKEGIVTSSDASEKEEIAKLLRFESSKSETASGR--MSLEEYYNAVPAEQQNIYYLAAPNRVLAESSPYYESLKKRNELVLFCYEPYDELVLMQLGKFKSKKLVSVEKEMREESKETTATTDFGEGSLLRSELDTLIPWLEEELRGQVIKVKATTRLDTHPCVITVEEM---AAARHFIRTQSHQVPEQNRFALLQPELEINPKHPIIKKLNKLRESD------KDLAQLIAKQLFANAMVGAGLA-EDPRMLLTNMNTLLSRAL 688

HSP 2 Score: 155.992 bits (393), Expect = 2.427e-39
Identity = 97/212 (45.75%), Postives = 138/212 (65.09%), Query Frame = 3

Query:   69 FQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLT--DPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFMEAL---QAG----ADISMIGQFGVGFYSSYLVADKVQVISKGN--DDEQYLWESSAGGSFTIK--PDTSEPLGRGSKIILFMKEDQVEYLXXXXXXXXXXXHSQFIGYPIKL 665
            FQAE  QLL ++  + YS+ E+F+RELISN+SDAL+K RY SL+    ++    + L I+I  DK    L I DTGIGMTK +L++NLGTIARSG+K F+E +   Q G    A  ++IGQFGVGFYSS++VA+KV+V ++    +     W +   G++ I+  PD       G++I+L +K D  EY +E +IK +IKK+S F+G PI L
Sbjct:   68 FQAETRQLLDIVARSLYSDHEVFVRELISNASDALEKFRYTSLSAGGENLAGKDRPLEIRITTDKPLMQLIIQDTGIGMTKEELVSNLGTIARSGSKKFLEQMKGTQQGASSEASSNIIGQFGVGFYSSFIVANKVEVFTRAAVPNAPGLRWSTDGSGTYEIEEVPDVE----LGTRIVLHLKTDCREYADEERIKAVIKKYSNFVGSPILL 275

[Close]

BLAST of Heat shock protein 90 vs. Ensembl Zebrafish
Match: hsp90aa1.1 (heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1 [Source:NCBI gene;Acc:30591])

HSP 1 Score: 669.463 bits (1726), Expect = 0.000e+0
Identity = 344/445 (77.30%), Postives = 393/445 (88.31%), Query Frame = 3

Query:  852 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNLKLGIHEDSVNRNKLADFLRYHSTSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSVMKALKTRVDADKNDKSVKDLVMLLYETSLLSSGFALEDPQIHANRIHRMIKLGLGX---XXXXXXXXXXXVGDVPVGPSATEDEAGKMEEVD 2177
            LNKTKPIWTRNPDD++ E+Y EFYKSL+NDWEDHLAVKHFSVEGQLEFRALLF P+RA FDLFENKKKRNNIKLYVRRVFIMDNCE+LIPEYLNF+KGVVDSEDLPLNISREMLQQ+KILKVIRKNLVKKCL+LF E+ EDKDNYKK+YEQF+KN+KLGIHEDS NR KL+D LRY++++SG+EM SLKDY+SRMK+ QK IYYITGE+KD VA+SAFVERL K G EV+YMI+PIDEY VQQLKEYDGK LV VTKEGLELPEDEEEKKK +E KA +E LCK+MKDILDKK+EKVTVSNRLVSSPCCIVTS +GW+ANMERIMK+QALRD+STMGYM AKKHLEINP H +++ L+ + +ADKNDK+VKDLV+LL+ET+LLSSGF L+DPQ HANRI+RMIKLGLGI   D    EI      D+PV     +D+  +MEEVD
Sbjct:  283 LNKTKPIWTRNPDDITNEEYGEFYKSLSNDWEDHLAVKHFSVEGQLEFRALLFVPRRAAFDLFENKKKRNNIKLYVRRVFIMDNCEELIPEYLNFIKGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLDLFTELAEDKDNYKKYYEQFSKNIKLGIHEDSQNRKKLSDLLRYYTSASGDEMVSLKDYVSRMKDTQKHIYYITGETKDQVANSAFVERLRKAGLEVIYMIEPIDEYCVQQLKEYDGKNLVSVTKEGLELPEDEEEKKKQDELKAKYENLCKIMKDILDKKIEKVTVSNRLVSSPCCIVTSTYGWTANMERIMKSQALRDNSTMGYMTAKKHLEINPAHPIVETLREKAEADKNDKAVKDLVILLFETALLSSGFTLDDPQTHANRIYRMIKLGLGIDDDDSVVEEISQPAEEDMPVLEG--DDDTSRMEEVD 725

HSP 2 Score: 341.273 bits (874), Expect = 8.804e-106
Identity = 171/213 (80.28%), Postives = 198/213 (92.96%), Query Frame = 3

Query:   57 ETFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKGNDDEQYLWESSAGGSFTIKPDTSEPLGRGSKIILFMKEDQVEYLXXXXXXXXXXXHSQFIGYPIKLVLEKERDKEV 695
            ETFAFQAEIAQL+SLIINTFYSNKEIFLRELISNSSDALDKIRY+SLTDPS LD+ K+L I++IPD+   TLTIIDTGIGMTK+DLINNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVA+KV VI+K NDDEQY+WES+AGGSFT+KPD  E +GRG+K+IL +KEDQ EY+EE++IKE++KKHSQFIGYPI L +EK+R+KEV
Sbjct:   15 ETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSCKDLKIELIPDQKERTLTIIDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYIWESAAGGSFTVKPDFGESIGRGTKVILHLKEDQSEYVEEKRIKEVVKKHSQFIGYPITLYIEKQREKEV 227

[Close]

Query:  852 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNLKLGIHEDSVNRNKLADFLRYHSTSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSVMKALKTRVDADKNDKSVKDLVMLLYETSLLSSGFALEDPQIHANRIHRMIKLGLGX---XXXXXXXXXXXVGDVPVGPSATEDEAGKMEEVD 2177
            LNKTKPIWTRNPDD++ E+Y EFYKSL+NDWEDHLAVKHFSVEGQLEFRALLF P+RA FDLFENKKKRNNIKLYVRRVFIMDNCE+LIPEYLNF+KGVVDSEDLPLNISREMLQQ+KILKVIRKNLVKKCL+LF E+ EDKDNYKK+YEQF+KN+KLGIHEDS NR KL+D LRY++++SG+EM SLKDY+SRMK+ QK IYYITGE+KD VA+SAFVERL K G EV+YMI+PIDEY VQQLKEYDGK LV VTKEGLELPEDEEEKKK +E KA +E LCK+MKDILDKK+EKVTVSNRLVSSPCCIVTS +GW+ANMERIMK+QALRD+STMGYM AKKHLEINP H +++ L+ + +ADKNDK+VKDLV+LL+ET+LLSSGF L+DPQ HANRI+RMIKLGLGI   D    EI      D+PV     +D+  +MEEVD
Sbjct:  283 LNKTKPIWTRNPDDITNEEYGEFYKSLSNDWEDHLAVKHFSVEGQLEFRALLFVPRRAAFDLFENKKKRNNIKLYVRRVFIMDNCEELIPEYLNFIKGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLDLFTELAEDKDNYKKYYEQFSKNIKLGIHEDSQNRKKLSDLLRYYTSASGDEMVSLKDYVSRMKDTQKHIYYITGETKDQVANSAFVERLRKAGLEVIYMIEPIDEYCVQQLKEYDGKNLVSVTKEGLELPEDEEEKKKQDELKAKYENLCKIMKDILDKKIEKVTVSNRLVSSPCCIVTSTYGWTANMERIMKSQALRDNSTMGYMTAKKHLEINPAHPIVETLREKAEADKNDKAVKDLVILLFETALLSSGFTLDDPQTHANRIYRMIKLGLGIDDDDSVVEEISQPAEEDMPVLEG--DDDTSRMEEVD 725

HSP 2 Score: 341.273 bits (874), Expect = 8.804e-106
Identity = 171/213 (80.28%), Postives = 198/213 (92.96%), Query Frame = 3

Query:   57 ETFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKGNDDEQYLWESSAGGSFTIKPDTSEPLGRGSKIILFMKEDQVEYLXXXXXXXXXXXHSQFIGYPIKLVLEKERDKEV 695
            ETFAFQAEIAQL+SLIINTFYSNKEIFLRELISNSSDALDKIRY+SLTDPS LD+ K+L I++IPD+   TLTIIDTGIGMTK+DLINNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVA+KV VI+K NDDEQY+WES+AGGSFT+KPD  E +GRG+K+IL +KEDQ EY+EE++IKE++KKHSQFIGYPI L +EK+R+KEV
Sbjct:   15 ETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSCKDLKIELIPDQKERTLTIIDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYIWESAAGGSFTVKPDFGESIGRGTKVILHLKEDQSEYVEEKRIKEVVKKHSQFIGYPITLYIEKQREKEV 227

[Close]

BLAST of Heat shock protein 90 vs. Ensembl Zebrafish
Match: hsp90ab1 (heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2 [Source:ZFIN;Acc:ZDB-GENE-031001-3])

HSP 1 Score: 663.3 bits (1710), Expect = 0.000e+0
Identity = 350/447 (78.30%), Postives = 396/447 (88.59%), Query Frame = 3

Query:  852 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNLKLGIHEDSVNRNKLADFLRYHSTSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSVMKALKTRVDADKNDKSVKDLVMLLYETSLLSSGFALEDPQIHANRIHRMIKLGLGXXX-----XXXXXXXXXVGDVPVGPSATEDEAGKMEEVD 2177
            LNKTKPIWTRNPDD+S E+Y EFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF P+RAPFDLFENKKK+NNIKLYVRRVFIMDNCE+LIPEYLNF++GVVDSEDLPLNISREMLQQ+KILKVIRKN+VKKCLELF E+ EDKDNYKKFY+ F+KNLKLGIHEDS NR KL++ LRY S+ SG+EMTSL +Y+SRMKENQK IYYITGESKD VAHSAFVER+ KRGFEVLYM +PIDEY VQQLK++DGK LV VTKEGLELPEDE+EKKK EE KA FE LCK+MK+ILDKKVEKVTVSNRLVSSPCCIVTS +GW+ANMERIMKAQALRD+STMGYM AKKHLEINPDH +M+ L+ + +ADKNDK+VKDLV+LL+ET+LLSSGF+L+DPQ H+NRI+RMIKLGLGIDE      +         D+P  P   +D+A +MEEVD
Sbjct:  281 LNKTKPIWTRNPDDISNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFAELAEDKDNYKKFYDAFSKNLKLGIHEDSQNRKKLSELLRYQSSQSGDEMTSLTEYVSRMKENQKSIYYITGESKDQVAHSAFVERVCKRGFEVLYMTEPIDEYCVQQLKDFDGKSLVSVTKEGLELPEDEDEKKKMEEDKAKFENLCKLMKEILDKKVEKVTVSNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIMETLRQKAEADKNDKAVKDLVILLFETALLSSGFSLDDPQTHSNRIYRMIKLGLGIDEDEDVPVEEPSSAAAPEDIP--PLEGDDDASRMEEVD 725

HSP 2 Score: 336.65 bits (862), Expect = 3.621e-104
Identity = 168/213 (78.87%), Postives = 195/213 (91.55%), Query Frame = 3

Query:   60 TFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKGNDDEQYLWESSAGGSFTIKPDTSEPLGRGSKIILFMKEDQVEYLXXXXXXXXXXXHSQFIGYPIKLVLEKERDKEVS 698
            TFAFQAEIAQL+SLIINTFYSNKEIFLREL+SN+SDALDKIRY+SLTDP+ LD+ K+L I IIP+    TLT+IDTGIGMTK+DLINNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVA+KV VI+K NDDEQY WESSAGGSFT+K D  EP+GRG+K+IL +KEDQ EY+EE+++KE++KKHSQFIGYPI L +EKERDKE+S
Sbjct:   13 TFAFQAEIAQLMSLIINTFYSNKEIFLRELVSNASDALDKIRYESLTDPTKLDSGKDLKIDIIPNVQERTLTLIDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVKVDHGEPIGRGTKVILHLKEDQTEYIEEKRVKEVVKKHSQFIGYPITLYVEKERDKEIS 225

[Close]

Query:  852 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNLKLGIHEDSVNRNKLADFLRYHSTSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSVMKALKTRVDADKNDKSVKDLVMLLYETSLLSSGFALEDPQIHANRIHRMIKLGLGXXX-----XXXXXXXXXVGDVPVGPSATEDEAGKMEEVD 2177
            LNKTKPIWTRNPDD+S E+Y EFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF P+RAPFDLFENKKK+NNIKLYVRRVFIMDNCE+LIPEYLNF++GVVDSEDLPLNISREMLQQ+KILKVIRKN+VKKCLELF E+ EDKDNYKKFY+ F+KNLKLGIHEDS NR KL++ LRY S+ SG+EMTSL +Y+SRMKENQK IYYITGESKD VAHSAFVER+ KRGFEVLYM +PIDEY VQQLK++DGK LV VTKEGLELPEDE+EKKK EE KA FE LCK+MK+ILDKKVEKVTVSNRLVSSPCCIVTS +GW+ANMERIMKAQALRD+STMGYM AKKHLEINPDH +M+ L+ + +ADKNDK+VKDLV+LL+ET+LLSSGF+L+DPQ H+NRI+RMIKLGLGIDE      +         D+P  P   +D+A +MEEVD
Sbjct:  281 LNKTKPIWTRNPDDISNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFAELAEDKDNYKKFYDAFSKNLKLGIHEDSQNRKKLSELLRYQSSQSGDEMTSLTEYVSRMKENQKSIYYITGESKDQVAHSAFVERVCKRGFEVLYMTEPIDEYCVQQLKDFDGKSLVSVTKEGLELPEDEDEKKKMEEDKAKFENLCKLMKEILDKKVEKVTVSNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIMETLRQKAEADKNDKAVKDLVILLFETALLSSGFSLDDPQTHSNRIYRMIKLGLGIDEDEDVPVEEPSSAAAPEDIP--PLEGDDDASRMEEVD 725

HSP 2 Score: 336.65 bits (862), Expect = 3.621e-104
Identity = 168/213 (78.87%), Postives = 195/213 (91.55%), Query Frame = 3

Query:   60 TFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKGNDDEQYLWESSAGGSFTIKPDTSEPLGRGSKIILFMKEDQVEYLXXXXXXXXXXXHSQFIGYPIKLVLEKERDKEVS 698
            TFAFQAEIAQL+SLIINTFYSNKEIFLREL+SN+SDALDKIRY+SLTDP+ LD+ K+L I IIP+    TLT+IDTGIGMTK+DLINNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVA+KV VI+K NDDEQY WESSAGGSFT+K D  EP+GRG+K+IL +KEDQ EY+EE+++KE++KKHSQFIGYPI L +EKERDKE+S
Sbjct:   13 TFAFQAEIAQLMSLIINTFYSNKEIFLRELVSNASDALDKIRYESLTDPTKLDSGKDLKIDIIPNVQERTLTLIDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVKVDHGEPIGRGTKVILHLKEDQTEYIEEKRVKEVVKKHSQFIGYPITLYVEKERDKEIS 225

[Close]

BLAST of Heat shock protein 90 vs. Ensembl Zebrafish
Match: hsp90aa1.2 (heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2 [Source:ZFIN;Acc:ZDB-GENE-031001-3])

HSP 1 Score: 652.899 bits (1683), Expect = 0.000e+0
Identity = 343/443 (77.43%), Postives = 399/443 (90.07%), Query Frame = 3

Query:  852 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNLKLGIHEDSVNRNKLADFLRYHSTSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSVMKALKTRVDADKNDKSVKDLVMLLYETSLLSSGFALEDPQIHANRIHRMIKLGLGXXXXXXXXXXXXVGDV-PVGPSATEDEAGKMEEVD 2177
            LNKTKP+WTRNPDD++ E+Y EFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF P+RAPFDLFENKKK+NNIKLYVRRVFIMDNC++LIPEYLNF+KGVVDSEDLPLNISREMLQQ+KILKVIRKNLVKKCLELF E+ EDKDNYKK+YEQF+KN+KLGIHEDS NR KL++ LRY++++SG+EM SLKDY++RMK+ QK IYYITGE+KD VA+SAFVERL K G EV+YMI+PIDEY VQQLKE++GK LV VTKEGLELPEDEEEKKK EE+K+ FE LCK+MKDIL+KKVEKVTVSNRLVSSPCCIVTS +GW+ANMERIMKAQALRD+STMGYMAAKKHLEINPDH +++ L+ + +ADKNDKSVKDLV+LL+ET+LLSSGF L+DPQ H+NRI+RMIKLGLGIDEDD+  +      +  + P   +D+  +MEEVD
Sbjct:  292 LNKTKPLWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENKKKKNNIKLYVRRVFIMDNCDELIPEYLNFIKGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKDNYKKYYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYVTRMKDTQKHIYYITGETKDQVANSAFVERLRKAGLEVIYMIEPIDEYCVQQLKEFEGKNLVSVTKEGLELPEDEEEKKKQEEKKSKFENLCKIMKDILEKKVEKVTVSNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHPIVETLRQKAEADKNDKSVKDLVILLFETALLSSGFTLDDPQTHSNRIYRMIKLGLGIDEDDLSAEEPSSAPIEEMPPLEGDDDTSRMEEVD 734

HSP 2 Score: 345.125 bits (884), Expect = 2.868e-107
Identity = 178/214 (83.18%), Postives = 199/214 (92.99%), Query Frame = 3

Query:   57 ETFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKGNDDEQYLWESSAGGSFTIKPDTSEPLGRGSKIILFMKEDQVEYLXXXXXXXXXXXHSQFIGYPIKLVLEKERDKEVS 698
            ETFAFQAEIAQL+SLIINTFYSNKEIFLRELISNSSDALDKIRY+SLTDPS LD+ K+L I+IIP+K+  TLTIIDTGIGMTK+DLINNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVA+KV VI+K  DDEQY WESSAGGSFT+K D SEP+GRG+K+IL +KEDQ EY+EER+IKEI+KKHSQFIGYPI L +EKERDKEVS
Sbjct:   16 ETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKDLKIEIIPNKEERTLTIIDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHLDDEQYAWESSAGGSFTVKVDNSEPIGRGTKVILHLKEDQTEYIEERRIKEIVKKHSQFIGYPITLFVEKERDKEVS 229

[Close]

BLAST of Heat shock protein 90 vs. Ensembl Xenopus
Match: ccdc173 (coiled-coil domain containing 173 [Source:Xenbase;Acc:XB-GENE-6258504])

HSP 1 Score: 979.163 bits (2530), Expect = 0.000e+0
Identity = 532/722 (73.68%), Postives = 625/722 (86.57%), Query Frame = 3

Query:   33 LMESMNDS-ETFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKGNDDEQYLWESSAGGSFTIKPDTSEPLGRGSKIILFMKEDQVEYLXXXXXXXXXXXHSQFIGYPIKLVLEKERDKEVSDDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXLNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNLKLGIHEDSVNRNKLADFLRYHSTSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSVMKALKTRVDADKNDKSVKDLVMLLYETSLLSSGFALEDPQIHANRIHRMIKLGLG----XXXXXXXXXXXXVGDVPVGPSATEDEAGKMEEVD 2177
            ++++M D  ETFAFQAEIAQL+SLIINTFYSNKEIFLRE+ISNSSDALDKIRY+SLTDPS LD+ KEL I +IP++   TLTIIDTGIGMTK+DLINNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVA+KV VI+K +DDEQY WESSAGGSFT++ D +EPLGRG+K+IL +KEDQ EYLEER+IKEI+K+HSQFIGYPI L +EKERDKE+SDDE+E +  +++ E+ +     +   DEE+D KK  KKKK  K K     +EELNKTKPIWTRNPDD++ E+Y EFYKSLTNDWEDHLAVKHFS+EGQLEFRALLF P+RAPFDLFE+KKK+NNIKLYVRRVFIMDNCE+LIPEYLN +KGVVDSEDLPLNISREMLQQ+KILKVIRKNLVKKCLELF E+ EDK+NYKK YEQF+KN+KLGIHEDS NR KL++ LRY+S++SG+EM SL +Y+SRMKENQK IYYITGE+KD V+HSAFVE L K G EV+YM +PIDEY VQQLKE+DGK LV VTKEGLELPEDEEEKKK EE+K  FE LCKV+K+ILDKKVEKV +SNRLV SPCCIVTS +GWSANMERIMKAQALRD+STMGYMAAKKHLEIN DH +++ L+ + +ADKNDKSVKDLV LL+ET+LLSSGF+L+DPQ H+NRI+RMIKLGLG       ++ E ++  + D+P  P   +++A +MEEVD
Sbjct:    1 MVQAMEDEVETFAFQAEIAQLMSLIINTFYSNKEIFLREIISNSSDALDKIRYESLTDPSKLDSGKELKIDLIPNRRDRTLTIIDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHSDDEQYAWESSAGGSFTVRADNTEPLGRGTKVILHLKEDQTEYLEERRIKEIVKRHSQFIGYPITLYMEKERDKEISDDESEEQIDEKKDEKKDKTEIEDVGSDEEEDAKKGDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSIEGQLEFRALLFVPRRAPFDLFESKKKKNNIKLYVRRVFIMDNCEELIPEYLNIIKGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELSEDKENYKKLYEQFSKNIKLGIHEDSQNRKKLSELLRYYSSASGDEMISLSEYVSRMKENQKHIYYITGETKDQVSHSAFVEGLRKHGLEVIYMTEPIDEYCVQQLKEFDGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKVIKEILDKKVEKVLLSNRLVESPCCIVTSTYGWSANMERIMKAQALRDNSTMGYMAAKKHLEINCDHPIIETLRQKAEADKNDKSVKDLVNLLFETALLSSGFSLDDPQTHSNRIYRMIKLGLGIDEDSFAEEEEEESPAIQDMP--PLEGDEDASRMEEVD 720

[Close]

BLAST of Heat shock protein 90 vs. Ensembl Xenopus
Match: ccdc173 (coiled-coil domain containing 173 [Source:Xenbase;Acc:XB-GENE-6258504])

HSP 1 Score: 976.852 bits (2524), Expect = 0.000e+0
Identity = 530/716 (74.02%), Postives = 621/716 (86.73%), Query Frame = 3

Query:   48 NDSETFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKGNDDEQYLWESSAGGSFTIKPDTSEPLGRGSKIILFMKEDQVEYLXXXXXXXXXXXHSQFIGYPIKLVLEKERDKEVSDDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXLNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNLKLGIHEDSVNRNKLADFLRYHSTSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSVMKALKTRVDADKNDKSVKDLVMLLYETSLLSSGFALEDPQIHANRIHRMIKLGLG----XXXXXXXXXXXXVGDVPVGPSATEDEAGKMEEVD 2177
            ++ ETFAFQAEIAQL+SLIINTFYSNKEIFLRE+ISNSSDALDKIRY+SLTDPS LD+ KEL I +IP++   TLTIIDTGIGMTK+DLINNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVA+KV VI+K +DDEQY WESSAGGSFT++ D +EPLGRG+K+IL +KEDQ EYLEER+IKEI+K+HSQFIGYPI L +EKERDKE+SDDE+E +  +++ E+ +     +   DEE+D KK  KKKK  K K     +EELNKTKPIWTRNPDD++ E+Y EFYKSLTNDWEDHLAVKHFS+EGQLEFRALLF P+RAPFDLFE+KKK+NNIKLYVRRVFIMDNCE+LIPEYLN +KGVVDSEDLPLNISREMLQQ+KILKVIRKNLVKKCLELF E+ EDK+NYKK YEQF+KN+KLGIHEDS NR KL++ LRY+S++SG+EM SL +Y+SRMKENQK IYYITGE+KD V+HSAFVE L K G EV+YM +PIDEY VQQLKE+DGK LV VTKEGLELPEDEEEKKK EE+K  FE LCKV+K+ILDKKVEKV +SNRLV SPCCIVTS +GWSANMERIMKAQALRD+STMGYMAAKKHLEIN DH +++ L+ + +ADKNDKSVKDLV LL+ET+LLSSGF+L+DPQ H+NRI+RMIKLGLG       ++ E ++  + D+P  P   +++A +MEEVD
Sbjct:    3 DEVETFAFQAEIAQLMSLIINTFYSNKEIFLREIISNSSDALDKIRYESLTDPSKLDSGKELKIDLIPNRRDRTLTIIDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHSDDEQYAWESSAGGSFTVRADNTEPLGRGTKVILHLKEDQTEYLEERRIKEIVKRHSQFIGYPITLYMEKERDKEISDDESEEQIDEKKDEKKDKTEIEDVGSDEEEDAKKGDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSIEGQLEFRALLFVPRRAPFDLFESKKKKNNIKLYVRRVFIMDNCEELIPEYLNIIKGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELSEDKENYKKLYEQFSKNIKLGIHEDSQNRKKLSELLRYYSSASGDEMISLSEYVSRMKENQKHIYYITGETKDQVSHSAFVEGLRKHGLEVIYMTEPIDEYCVQQLKEFDGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKVIKEILDKKVEKVLLSNRLVESPCCIVTSTYGWSANMERIMKAQALRDNSTMGYMAAKKHLEINCDHPIIETLRQKAEADKNDKSVKDLVNLLFETALLSSGFSLDDPQTHSNRIYRMIKLGLGIDEDSFAEEEEEESPAIQDMP--PLEGDEDASRMEEVD 716

[Close]

BLAST of Heat shock protein 90 vs. Ensembl Xenopus
Match: uck1 (uridine-cytidine kinase 1 [Source:Xenbase;Acc:XB-GENE-961187])

HSP 1 Score: 973 bits (2514), Expect = 0.000e+0
Identity = 516/709 (72.78%), Postives = 603/709 (85.05%), Query Frame = 3

Query:   57 ETFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKGNDDEQYLWESSAGGSFTIKPDTSEPLGRGSKIILFMKEDQVEYLXXXXXXXXXXXHSQFIGYPIKLVLEKERDKEVSDDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNLKLGIHEDSVNRNKLADFLRYHSTSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSVMKALKTRVDADKNDKSVKDLVMLLYETSLLSSGFALEDPQIHANRIHRMIKLGLGX--XXXXXXXXXXXVGDVPVGPSATEDEAGKMEEVD 2177
            ETFAFQAEIAQL+SLIINTFYSNKEIFLRELISN+SDALDKIRY+SLTDPS LD+ K+L I IIP++   TLT+IDTGIGMTK+DLINNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVA+KV VI+K NDDEQY WESSAGGSFT+K D  EP+GRG+K+IL++KEDQ EYLEE+++KE +KKHSQFIGYPI L LEKER+KE+SDDE +    +++  + E+                                 LNKTKPIWTRNPDD++QE+Y EFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF P+RAPFDLFENKKK+NNIKLYVRRVFIMD+C++LIPEYLNF++GVVDSEDLPLNISREMLQQ+KILKVIRKN+VKKCLELF E+ EDK+NYKKFYE F+KNLKLGIHEDS NR KL++ LRYH++ +G+EM SL +Y+SRMKENQK IYYITGESKD VA+SAFVER+ KRGFEV+YM +PIDEY VQQLKE+DGK LV VTKEGLELPEDEEEKK  EE K  FE LCK+MK+ILDKKVEKVTVSNRLVSSPCCIVTS +GW+ANMERIMKAQALRD+STMGYM AKKHLEINP+H +++ L+ + + DKNDK+VKDLV+LL+ET+LLSSGF+L+DPQ H+NRI+RMIKLGLGI  D+  +E  +  V D  + P   +++A +MEEVD
Sbjct:   13 ETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKDLKIDIIPNRQERTLTVIDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVLVITKHNDDEQYAWESSAGGSFTVKTDHGEPIGRGTKVILYLKEDQTEYLEEKRVKETVKKHSQFIGYPITLYLEKEREKEISDDENDKPKIEDKYIDQEE---------------------------------LNKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFTELAEDKENYKKFYEAFSKNLKLGIHEDSTNRKKLSELLRYHTSQTGDEMASLTEYVSRMKENQKSIYYITGESKDQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKTLVSVTKEGLELPEDEEEKKMMEENKTKFESLCKLMKEILDKKVEKVTVSNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINPEHPIVETLRQKAETDKNDKAVKDLVVLLFETALLSSGFSLDDPQTHSNRIYRMIKLGLGIDDDDATVEETSPSVAD-EIPPLEGDEDASRMEEVD 687

[Close]

BLAST of Heat shock protein 90 vs. Ensembl Xenopus
Match: ccdc173 (coiled-coil domain containing 173 [Source:Xenbase;Acc:XB-GENE-6258504])

HSP 1 Score: 959.903 bits (2480), Expect = 0.000e+0
Identity = 526/721 (72.95%), Postives = 617/721 (85.58%), Query Frame = 3

Query:   36 MESMNDS-ETFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKGNDDEQYLWESSAGGSFTIKPDTSEPLGRGSKIILFMKEDQVEYLXXXXXXXXXXXHSQFIGYPIKLVLEKERDKEVSDDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXLNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNLKLGIHEDSVNRNKLADFLRYHSTSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSVMKALKTRVDADKNDKSVKDLVMLLYETSLLSSGFALEDPQIHANRIHRMIKLGLG----XXXXXXXXXXXXVGDVPVGPSATEDEAGKMEEVD 2177
            +++M D  ETFAFQAEIAQL+SLIINTFYSNKEIFLRE+ISNSSDALDKIRY+SLTDPS LD+ KEL I +IP++   TLTIIDTGIGMTK+DLINNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVA+KV VI+K +DDEQY WESSAGGSFT++ D +EPLGRG+K+IL +KEDQ EYLEER+IKEI+K+HSQFIGYPI L        E+SDDE+E +  +++ E+ +     +   DEE+D KK  KKKK  K K     +EELNKTKPIWTRNPDD++ E+Y EFYKSLTNDWEDHLAVKHFS+EGQLEFRALLF P+RAPFDLFE+KKK+NNIKLYVRRVFIMDNCE+LIPEYLN +KGVVDSEDLPLNISREMLQQ+KILKVIRKNLVKKCLELF E+ EDK+NYKK YEQF+KN+KLGIHEDS NR KL++ LRY+S++SG+EM SL +Y+SRMKENQK IYYITGE+KD V+HSAFVE L K G EV+YM +PIDEY VQQLKE+DGK LV VTKEGLELPEDEEEKKK EE+K  FE LCKV+K+ILDKKVEKV +SNRLV SPCCIVTS +GWSANMERIMKAQALRD+STMGYMAAKKHLEIN DH +++ L+ + +ADKNDKSVKDLV LL+ET+LLSSGF+L+DPQ H+NRI+RMIKLGLG       ++ E ++  + D+P  P   +++A +MEEVD
Sbjct:    5 VQAMEDEVETFAFQAEIAQLMSLIINTFYSNKEIFLREIISNSSDALDKIRYESLTDPSKLDSGKELKIDLIPNRRDRTLTIIDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHSDDEQYAWESSAGGSFTVRADNTEPLGRGTKVILHLKEDQTEYLEERRIKEIVKRHSQFIGYPITLY-------EISDDESEEQIDEKKDEKKDKTEIEDVGSDEEEDAKKGDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSIEGQLEFRALLFVPRRAPFDLFESKKKKNNIKLYVRRVFIMDNCEELIPEYLNIIKGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELSEDKENYKKLYEQFSKNIKLGIHEDSQNRKKLSELLRYYSSASGDEMISLSEYVSRMKENQKHIYYITGETKDQVSHSAFVEGLRKHGLEVIYMTEPIDEYCVQQLKEFDGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKVIKEILDKKVEKVLLSNRLVESPCCIVTSTYGWSANMERIMKAQALRDNSTMGYMAAKKHLEINCDHPIIETLRQKAEADKNDKSVKDLVNLLFETALLSSGFSLDDPQTHSNRIYRMIKLGLGIDEDSFAEEEEEESPAIQDMP--PLEGDEDASRMEEVD 716

[Close]

BLAST of Heat shock protein 90 vs. Ensembl Xenopus
Match: ccdc173 (coiled-coil domain containing 173 [Source:Xenbase;Acc:XB-GENE-6258504])

HSP 1 Score: 921.768 bits (2381), Expect = 0.000e+0
Identity = 512/716 (71.51%), Postives = 602/716 (84.08%), Query Frame = 3

Query:   48 NDSETFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKGNDDEQYLWESSAGGSFTIKPDTSEPLGRGSKIILFMKEDQVEYLXXXXXXXXXXXHSQFIGYPIKLVLEKERDKEVSDDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXLNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNLKLGIHEDSVNRNKLADFLRYHSTSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSVMKALKTRVDADKNDKSVKDLVMLLYETSLLSSGFALEDPQIHANRIHRMIKLGLG----XXXXXXXXXXXXVGDVPVGPSATEDEAGKMEEVD 2177
            ++ ETFAFQAEIAQL+SLIINTFYSNKEIFLRE+ISNSSDALDKIRY+SLTDPS LD+ KEL I +IP++   TLTIIDTGIGMTK+DLINNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVA+KV VI+K +DDEQY WESSAGGSFT++ D +EPLGRG+K+IL +KEDQ EYLEER+IKEI+K+HSQFIGYPI L +EKERDKE+SDDE+E +  +++ E+ +     +   DEE+D KK  KKKK  K K     +EELNKTKPIWTRNPDD++ E+Y EFYKSLTNDWEDHLAVKHFS+EGQLEFRALLF P+RAPFDLFE+KKK+NNIKLYVRRVFIMDNCE+LIPEYLN +KGVVDSEDLPLNISREMLQQ+KILKVIRKNLVKKCLELF E+ EDK+NYKK YEQF+KN+KLGIHEDS NR KL++ LRY+S++SG+EM SL +Y+SRMKENQK IYYITGE+KD V+HSAFVE L K G EV+YM +PIDEY VQQLKE+DGK LV VTKEGLELPEDEEEKKK EE+K  FE LCKV+K+ILDKKVEKV +SN                     RIMKAQALRD+STMGYMAAKKHLEIN DH +++ L+ + +ADKNDKSVKDLV LL+ET+LLSSGF+L+DPQ H+NRI+RMIKLGLG       ++ E ++  + D+P  P   +++A +MEEVD
Sbjct:    3 DEVETFAFQAEIAQLMSLIINTFYSNKEIFLREIISNSSDALDKIRYESLTDPSKLDSGKELKIDLIPNRRDRTLTIIDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHSDDEQYAWESSAGGSFTVRADNTEPLGRGTKVILHLKEDQTEYLEERRIKEIVKRHSQFIGYPITLYMEKERDKEISDDESEEQIDEKKDEKKDKTEIEDVGSDEEEDAKKGDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSIEGQLEFRALLFVPRRAPFDLFESKKKKNNIKLYVRRVFIMDNCEELIPEYLNIIKGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELSEDKENYKKLYEQFSKNIKLGIHEDSQNRKKLSELLRYYSSASGDEMISLSEYVSRMKENQKHIYYITGETKDQVSHSAFVEGLRKHGLEVIYMTEPIDEYCVQQLKEFDGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKVIKEILDKKVEKVLLSN---------------------RIMKAQALRDNSTMGYMAAKKHLEINCDHPIIETLRQKAEADKNDKSVKDLVNLLFETALLSSGFSLDDPQTHSNRIYRMIKLGLGIDEDSFAEEEEEESPAIQDMP--PLEGDEDASRMEEVD 695

[Close]

BLAST of Heat shock protein 90 vs. Ensembl Mouse
Match: Hsp90aa1 (heat shock protein 90, alpha (cytosolic), class A member 1 [Source:MGI Symbol;Acc:MGI:96250])

HSP 1 Score: 676.396 bits (1744), Expect = 0.000e+0
Identity = 348/445 (78.20%), Postives = 401/445 (90.11%), Query Frame = 3

Query:  852 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNLKLGIHEDSVNRNKLADFLRYHSTSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSVMKALKTRVDADKNDKSVKDLVMLLYETSLLSSGFALEDPQIHANRIHRMIKLGLGXXXXXXXXXXXXVG---DVPVGPSATEDEAGKMEEVD 2177
            LNKTKPIWTRNPDD++ E+Y EFYKSLTNDWE+HLAVKHFSVEGQLEFRALLF P+RAPFDLFEN+KK+NNIKLYVRRVFIMDNCE+LIPEYLNF++GVVDSEDLPLNISREMLQQ+KILKVIRKNLVKKCLELF E+ EDK+NYKKFYEQF+KN+KLGIHEDS NR KL++ LRY++++SG+EM SLKDY +RMKENQK IY+ITGE+KD VA+SAFVERL K G EV+YMI+PIDEY VQQLKE++GK LV VTKEGLELPEDEEEKKK EE+K  FE LCK+MKDIL+KKVEKV VSNRLV+SPCCIVTS +GW+ANMERIMKAQALRD+STMGYMAAKKHLEINPDHS+++ L+ + +ADKNDKSVKDLV+LLYET+LLSSGF+LEDPQ HANRI+RMIKLGLGIDEDD  +D T      ++P  P   +D+  +MEEVD
Sbjct:  291 LNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEEHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYFITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTVDDTSAAVTEEMP--PLEGDDDTSRMEEVD 733

HSP 2 Score: 352.829 bits (904), Expect = 3.480e-110
Identity = 180/216 (83.33%), Postives = 199/216 (92.13%), Query Frame = 3

Query:   57 ETFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKGNDDEQYLWESSAGGSFTIKPDTSEPLGRGSKIILFMKEDQVEYLXXXXXXXXXXXHSQFIGYPIKLVLEKERDKEVSDD 704
            ETFAFQAEIAQL+SLIINTFYSNKEIFLRELISNSSDALDKIRY+SLTDPS LD+ KEL I +IP K   TLTI+DTGIGMTK+DLINNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVA+KV VI+K NDDEQY WESSAGGSFT++ DT EP+GRG+K+IL +KEDQ EYLEER+IKEI+KKHSQFIGYPI L +EKERDKEVSDD
Sbjct:   18 ETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPSKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDD 233

[Close]

Query:  852 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNLKLGIHEDSVNRNKLADFLRYHSTSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSVMKALKTRVDADKNDKSVKDLVMLLYETSLLSSGFALEDPQIHANRIHRMIKLGLGXXXXXXXXXXXXVG---DVPVGPSATEDEAGKMEEVD 2177
            LNKTKPIWTRNPDD++ E+Y EFYKSLTNDWE+HLAVKHFSVEGQLEFRALLF P+RAPFDLFEN+KK+NNIKLYVRRVFIMDNCE+LIPEYLNF++GVVDSEDLPLNISREMLQQ+KILKVIRKNLVKKCLELF E+ EDK+NYKKFYEQF+KN+KLGIHEDS NR KL++ LRY++++SG+EM SLKDY +RMKENQK IY+ITGE+KD VA+SAFVERL K G EV+YMI+PIDEY VQQLKE++GK LV VTKEGLELPEDEEEKKK EE+K  FE LCK+MKDIL+KKVEKV VSNRLV+SPCCIVTS +GW+ANMERIMKAQALRD+STMGYMAAKKHLEINPDHS+++ L+ + +ADKNDKSVKDLV+LLYET+LLSSGF+LEDPQ HANRI+RMIKLGLGIDEDD  +D T      ++P  P   +D+  +MEEVD
Sbjct:  291 LNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEEHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYFITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTVDDTSAAVTEEMP--PLEGDDDTSRMEEVD 733

HSP 2 Score: 352.829 bits (904), Expect = 3.480e-110
Identity = 180/216 (83.33%), Postives = 199/216 (92.13%), Query Frame = 3

Query:   57 ETFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKGNDDEQYLWESSAGGSFTIKPDTSEPLGRGSKIILFMKEDQVEYLXXXXXXXXXXXHSQFIGYPIKLVLEKERDKEVSDD 704
            ETFAFQAEIAQL+SLIINTFYSNKEIFLRELISNSSDALDKIRY+SLTDPS LD+ KEL I +IP K   TLTI+DTGIGMTK+DLINNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVA+KV VI+K NDDEQY WESSAGGSFT++ DT EP+GRG+K+IL +KEDQ EYLEER+IKEI+KKHSQFIGYPI L +EKERDKEVSDD
Sbjct:   18 ETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPSKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDD 233

[Close]

BLAST of Heat shock protein 90 vs. Ensembl Mouse
Match: Hsp90ab1 (heat shock protein 90 alpha (cytosolic), class B member 1 [Source:MGI Symbol;Acc:MGI:96247])

HSP 1 Score: 656.366 bits (1692), Expect = 0.000e+0
Identity = 344/444 (77.48%), Postives = 400/444 (90.09%), Query Frame = 3

Query:  852 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNLKLGIHEDSVNRNKLADFLRYHSTSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSVMKALKTRVDADKNDKSVKDLVMLLYETSLLSSGFALEDPQIHANRIHRMIKLGLGXXXXXXXXXXXXVGDVP--VGPSATEDEAGKMEEVD 2177
            LNKTKPIWTRNPDD++QE+Y EFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF P+RAPFDLFENKKK+NNIKLYVRRVFIMD+C++LIPEYLNF++GVVDSEDLPLNISREMLQQ+KILKVIRKN+VKKCLELF E+ EDK+NYKKFYE F+KNLKLGIHEDS NR +L++ LRYH++ SG+EMTSL +Y+SRMKE QK IYYITGESK+ VA+SAFVER+ KRGFEV+YM +PIDEY VQQLKE+DGK LV VTKEGLELPEDEEEKKK EE KA FE LCK+MK+ILDKKVEKVT+SNRLVSSPCCIVTS +GW+ANMERIMKAQALRD+STMGYM AKKHLEINPDH +++ L+ + +ADKNDK+VKDLV+LL+ET+LLSSGF+LEDPQ H+NRI+RMIKLGLGIDED++  +      VP  + P   +++A +MEEVD
Sbjct:  282 LNKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGDEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEGLELPEDEEEKKKMEESKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEADKNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNRIYRMIKLGLGIDEDEVTAEEPSAA-VPDEIPPLEGDEDASRMEEVD 724

HSP 2 Score: 339.732 bits (870), Expect = 2.622e-105
Identity = 171/213 (80.28%), Postives = 195/213 (91.55%), Query Frame = 3

Query:   60 TFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKGNDDEQYLWESSAGGSFTIKPDTSEPLGRGSKIILFMKEDQVEYLXXXXXXXXXXXHSQFIGYPIKLVLEKERDKEVS 698
            TFAFQAEIAQL+SLIINTFYSNKEIFLRELISN+SDALDKIRY+SLTDPS LD+ KEL I IIP+    TLT++DTGIGMTK+DLINNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVA+KV VI+K NDDEQY WESSAGGSFT++ D  EP+GRG+K+IL +KEDQ EYLEER++KE++KKHSQFIGYPI L LEKER+KE+S
Sbjct:   14 TFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHGEPIGRGTKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEIS 226

[Close]

BLAST of Heat shock protein 90 vs. Ensembl Mouse
Match: Hsp90b1 (heat shock protein 90, beta (Grp94), member 1 [Source:MGI Symbol;Acc:MGI:98817])

HSP 1 Score: 379.793 bits (974), Expect = 1.099e-119
Identity = 200/413 (48.43%), Postives = 283/413 (68.52%), Query Frame = 3

Query:  852 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFE--NKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNLKLGIHEDSVNRNKLADFLRYHSTSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKD-ILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQAL---RDSSTMGYMAAKKHLEINPDHSVMKALKTRVDADKNDKSVKDLVMLLYETSLLSSGFALEDPQIHANRIHRMIKLGL 2072
            +N  KPIW R   +V +++Y  FYKS + + +D +A  HF+ EG++ F+++LF P  AP  LF+    KK + IKLYVRRVFI D+  D++P+YLNFVKGVVDS+DLPLN+SRE LQQ+K+LKVIRK LV+K L++ ++I ++K N   F+++F  N+KLG+ ED  NR +LA  LR+ S+    ++TSL  Y+ RMKE Q  IY++ G S+     S FVERL K+G+EV+Y+ +P+DEY +Q L E+DGK+   V KEG++  E E+ K+  E  +  FEPL   MKD  L  K+EK  VS RL  SPC +V SQ+GWS NMERIMKAQA    +D ST  Y + KK  EINP H +++ +  R+  D++DK+V DL ++L+ET+ L SG+ L D + + +RI RM++L L
Sbjct:  336 MNDIKPIWQRPSKEVEEDEYKAFYKSFSKESDDPMAYIHFTAEGEVTFKSILFVPTSAPRGLFDEYGSKKSDYIKLYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKTLDMIKKIADEKYN-DTFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSHHSTDITSLDQYVERMKEKQDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAKEGVKFDESEKTKESREATEKEFEPLLNWMKDKALKDKIEKAVVSQRLTESPCALVASQYGWSGNMERIMKAQAYQTGKDISTNYYASQKKTFEINPRHPLIRDMLRRIKEDEDDKTVMDLAVVLFETATLRSGYLLPDTKAYGDRIERMLRLSL 747

HSP 2 Score: 205.682 bits (522), Expect = 1.689e-55
Identity = 112/207 (54.11%), Postives = 146/207 (70.53%), Query Frame = 3

Query:   54 SETFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFM----EALQAGADIS-MIGQFGVGFYSSYLVADKVQVISKGNDDEQYLWESSAGGSFTIKPDTSEPLGRGSKIILFMKEDQVEYLXXXXXXXXXXXHSQFIGYPI 659
            SE FAFQAE+ +++ LIIN+ Y NKEIFLRELISN+SDALDKIR  SLTD + L   +EL +KI  DK+   L + DTG+GMT+ +L+ NLGTIA+SGT  F+    EA + G   S +IGQFGVGFYS++LVADKV V SK N+D Q++WES +     I       LGRG+ I L +KE+  +YLE   IK +++K+SQFI +PI
Sbjct:   73 SEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALAGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDGQSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESDSNEFSVIADPRGNTLGRGTTITLVLKEEASDYLELDTIKNLVRKYSQFINFPI 279

[Close]

BLAST of Heat shock protein 90 vs. Ensembl Mouse
Match: Hsp90aa1 (heat shock protein 90, alpha (cytosolic), class A member 1 [Source:MGI Symbol;Acc:MGI:96250])

HSP 1 Score: 311.612 bits (797), Expect = 2.059e-101
Identity = 150/181 (82.87%), Postives = 166/181 (91.71%), Query Frame = 3

Query:   57 ETFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKGNDDEQYLWESSAGGSFTIKPDTSEPLGRGSKIILFMKEDQVEYL 599
            ETFAFQAEIAQL+SLIINTFYSNKEIFLRELISNSSDALDKIRY+SLTDPS LD+ KEL I +IP K   TLTI+DTGIGMTK+DLINNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVA+KV VI+K NDDEQY WESSAGGSFT++ DT EP+GRG+K+IL +KEDQ EYL
Sbjct:   18 ETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPSKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYL 198

[Close]

BLAST of Heat shock protein 90 vs. UniProt/SwissProt
Match: sp|P30946|HS90A_RABIT (Heat shock protein HSP 90-alpha OS=Oryctolagus cuniculus OX=9986 GN=HSP90AA1 PE=1 SV=2)

HSP 1 Score: 997.268 bits (2577), Expect = 0.000e+0
Identity = 518/710 (72.96%), Postives = 597/710 (84.08%), Query Frame = 3

Query:   57 ETFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKGNDDEQYLWESSAGGSFTIKPDTSEPLGRGSKIILFMKEDQVEYLXXXXXXXXXXXHSQFIGYPIKLVLEKERDKEVSDDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNLKLGIHEDSVNRNKLADFLRYHSTSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSVMKALKTRVDADKNDKSVKDLVMLLYETSLLSSGFALEDPQIHANRIHRMIKLGLGXXXXXXXXXXXXVG---DVPVGPSATEDEAGKMEEVD 2177
            ETFAFQAEIAQL+SLIINTFYSNKEIFLRELISNSSDALDKIRY+SLTDPS LD+ KEL I +IP+K   TLTI+DTGIGMTK+DLINNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVA+KV VI+K NDDEQY WESSAGGSFT++ D  EP+GRG+K++L +KEDQ EYLEER+IKEI+KKHSQFIGYPI L +EKERDKEVSDDEA+    K E E+     + E+  D + D ++                 LNKTKPIWTRNPDD++ E+Y EFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF P+RAPFDLFEN+KK+NNIKLYVRRVFIMDNCE+LIPEYLNF++GVVDSEDLPLNISREMLQQ+KILKVIRKNLVKKCLELF E+ EDK+NYKKFYEQF+KN+KLGIHEDS NR KL++ LRY++++SG+EM SLKDY +RMKENQK IYYITGE+KD VA+SAFVERL K G EV+YMI+PIDEY VQQLKE++GK LV VT              K   +   FE LCK+MKDIL+KKVEKV VSNRLV+SPCCIVTS +GW+ANMERIMKAQALRD+STMGYMAAKKHLE+NPDHS+++ L+ + +ADKNDKSVKDLV+LLYET+LLSSGF+LEDPQ HANRI+RMIKLGLGIDEDD   D T      ++P  P   +D+  +MEEVD
Sbjct:   18 ETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDAGEPMGRGTKVVLHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAKQPDDKPEIEDVGSDEEEEEKKDGDIDQEE-----------------LNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVT--------------KEGLELTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEVNPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTAAAVTEEMP--PLEGDDDTSRMEEVD 694

[Close]

BLAST of Heat shock protein 90 vs. UniProt/SwissProt
Match: sp|P02828|HSP83_DROME (Heat shock protein 83 OS=Drosophila melanogaster OX=7227 GN=Hsp83 PE=1 SV=1)

HSP 1 Score: 987.638 bits (2552), Expect = 0.000e+0
Identity = 542/715 (75.80%), Postives = 620/715 (86.71%), Query Frame = 3

Query:   51 DSETFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKGNDDEQYLWESSAGGSFTIKPDTSEPLGRGSKIILFMKEDQVEYLXXXXXXXXXXXHSQFIGYPIKLVL----EKERDKEVSDDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNLKLGIHEDSVNRNKLADFLRYHSTSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSVMKALKTRVDADKNDKSVKDLVMLLYETSLLSSGFALEDPQIHANRIHRMIKLGLGXXXXXXXXX--XXXVGDVPVGPSATEDEAGKMEEVD 2177
            ++ETFAFQAEIAQL+SLIINTFYSNKEIFLRELISN+SDALDKIRY+SLTDPS LD+ KEL IK+IP+K AGTLTIIDTGIGMTKSDL+NNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVADKV V SK NDDEQY+WESSAGGSFT++ D SEPLGRG+KI+L++KEDQ +YLEE KIKEI+ KHSQFIGYPIKL++    EKE   + +DDE +   +K+E E  E K +    D++ D   KD KKKK IKEKY ++EELNKTKPIWTRNPDD+SQE+Y EFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF P+R PFDLFEN+KKRNNIKLYVRRVFIMDNCEDLIPEYLNF+KGVVDSEDLPLNISREMLQQNK+LKVIRKNLVKK +EL EE+ EDK+NYKKFY+QF+KNLKLG+HEDS NR KLADFLR+H+++SG++  SL DY+SRMK+NQK +Y+ITGESKD V++SAFVER+  RGFEV+YM +PIDEY +Q LKEY GK+LV VTKEGLELPEDE EKKK EE KA FE LCK+MK ILD KVEKV VSNRLV SPCCIVTSQFGWSANMERIMKAQALRD++TMGYMA KK LEINPDH +++ L+ + DADKNDK+VKDLV+LL+ETSLLSSGF+L+ PQ+HA+RI+RMIKLGLGIDED+          GD P     TED A  MEEVD
Sbjct:    4 EAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELYIKLIPNKTAGTLTIIDTGIGMTKSDLVNNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVADKVTVTSKNNDDEQYVWESSAGGSFTVRADNSEPLGRGTKIVLYIKEDQTDYLEESKIKEIVNKHSQFIGYPIKLLVEKEREKEVSDDEADDEKKEGDEKKEMETDEPKIEDVGEDEDADKKDKDAKKKKTIKEKYTEDEELNKTKPIWTRNPDDISQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRTPFDLFENQKKRNNIKLYVRRVFIMDNCEDLIPEYLNFMKGVVDSEDLPLNISREMLQQNKVLKVIRKNLVKKTMELIEELTEDKENYKKFYDQFSKNLKLGVHEDSNNRAKLADFLRFHTSASGDDFCSLADYVSRMKDNQKHVYFITGESKDQVSNSAFVERVKARGFEVVYMTEPIDEYVIQHLKEYKGKQLVSVTKEGLELPEDESEKKKREEDKAKFESLCKLMKSILDNKVEKVVVSNRLVDSPCCIVTSQFGWSANMERIMKAQALRDTATMGYMAGKKQLEINPDHPIVETLRQKADADKNDKAVKDLVILLFETSLLSSGFSLDSPQVHASRIYRMIKLGLGIDEDEPMTTDDAQSAGDAPSLVEDTED-ASHMEEVD 717

[Close]

BLAST of Heat shock protein 90 vs. UniProt/SwissProt
Match: sp|P04809|HSP83_DROPS (Heat shock protein 83 OS=Drosophila pseudoobscura pseudoobscura OX=46245 GN=Hsp83 PE=3 SV=2)

HSP 1 Score: 986.867 bits (2550), Expect = 0.000e+0
Identity = 540/715 (75.52%), Postives = 618/715 (86.43%), Query Frame = 3

Query:   51 DSETFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKGNDDEQYLWESSAGGSFTIKPDTSEPLGRGSKIILFMKEDQVEYLXXXXXXXXXXXHSQFIGYPIKLVL----EKERDKEVSDDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNLKLGIHEDSVNRNKLADFLRYHSTSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSVMKALKTRVDADKNDKSVKDLVMLLYETSLLSSGFALEDPQIHANRIHRMIKLGLG--XXXXXXXXXXXXVGDVPVGPSATEDEAGKMEEVD 2177
            ++ETFAFQAEIAQL+SLIINTFYSNKEIFLRELISN+SDALDKIRY+SLTDPS LD+ KEL IK+IP+K AGTLTIIDTGIGMTKSDL+NNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YL+AD+V V SK NDDEQY+WESSAGGSFT+K D SEPLGRG+KI+L++KEDQ +YLEE KIKEI+ KHSQFIGYPIKL++    EKE   + +DDE + +  K++ +  E K +    D++ D   KD KKKK IKEKY ++EELNKTKPIWTRNPDD+SQE+Y EFYKSLTNDWEDHL VKHFSVEGQLEFRALLF P+R PFDLFEN+KKRNNIKLYVRRVFIMDNCEDLIPEYLNF+KGVVDSEDLPLNISREMLQQNK+LKVIRKNLVKK +EL EE+ EDK+NYKKFYEQF+KNLKLG+HEDS NR KLADFLR+H+++SG++  SL DY+SRMKENQK +Y+ITGESKD V++SAFVER+  RGFEV+YM +PIDEY +Q LKEY GK+LV VTKEGLELPEDE EKKK EE KA FE LCK+MK ILD KVEKV VSNRLV SPCCIVTSQFGWSANMERIMKAQALRD++TMGYMA KK LEINPDH +++AL+ + DADKNDK+VKDLV+LL+ETSLLSSGF+L+ PQ+HA+RI+RMIKLGLG   DE     D    GD P     TED A  MEEVD
Sbjct:    4 EAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELYIKLIPNKTAGTLTIIDTGIGMTKSDLVNNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLIADRVTVTSKNNDDEQYVWESSAGGSFTVKADNSEPLGRGTKIVLYIKEDQTDYLEESKIKEIVNKHSQFIGYPIKLLVEKEREKEVSDDEADDEKKDDEAKKDMDTDEPKIEDVGEDEDADKKDKDGKKKKTIKEKYTEDEELNKTKPIWTRNPDDISQEEYGEFYKSLTNDWEDHLCVKHFSVEGQLEFRALLFIPRRTPFDLFENQKKRNNIKLYVRRVFIMDNCEDLIPEYLNFIKGVVDSEDLPLNISREMLQQNKVLKVIRKNLVKKTMELIEELTEDKENYKKFYEQFSKNLKLGVHEDSNNRAKLADFLRFHTSASGDDFCSLSDYVSRMKENQKHVYFITGESKDQVSNSAFVERVKARGFEVVYMTEPIDEYVIQHLKEYKGKQLVSVTKEGLELPEDEAEKKKREEDKAKFEGLCKLMKSILDSKVEKVVVSNRLVDSPCCIVTSQFGWSANMERIMKAQALRDTATMGYMAGKKQLEINPDHPIVEALRQKADADKNDKAVKDLVILLFETSLLSSGFSLDSPQVHASRIYRMIKLGLGIDEDEPMTTEDAHSGGDAPGLVEDTED-ASHMEEVD 717

[Close]

BLAST of Heat shock protein 90 vs. UniProt/SwissProt
Match: sp|P06660|HSP85_TRYCR (Heat shock-like 85 kDa protein OS=Trypanosoma cruzi OX=5693 PE=3 SV=1)

HSP 1 Score: 846.269 bits (2185), Expect = 0.000e+0
Identity = 444/673 (65.97%), Postives = 554/673 (82.32%), Query Frame = 3

Query:   54 SETFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKGNDDEQYLWESSAGGSFTIKPDTSEPLGRGSKIILFMKEDQVEYLXXXXXXXXXXXHSQFIGYPIKLVLEKERDKEVSDDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNLKLGIHEDSVNRNKLADFLRYHSTSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSVMKALKTRVDADKNDKSVKDLVMLLYETSLLSSGFALEDPQIHANRIHRMIKLGL 2072
            +ETFAFQAEI QL+SLIINTFYSNKEIFLRELISNSSDA DKIRY+SLT+ +VL     L I+++PDK   TLT+ DTGIGMTK++L+NNLGTIARSGTKAFMEAL+AG D+SMIGQFGVGFYS+YLVAD+V V+SK NDDE Y WESSAGG+FT+ P     L RG++I+L +KEDQ EYLEER++K++IKKHS+FIGY I+L++EK  +KEV+D++ +     +  E  E K +    D EE + KK  KK K++ ++++ +   NK KP+WTR+P DV++E+YA FYK+++NDWE+ L+ KHFSVEGQLEFRA+LF PKRAPFD+FE  KKRNNIKLYVRRVFIMDNCEDL PE+L FV+GVVDSEDLPLNISRE LQQNKILKVIRKN+VKK LELFEEI E+K++YKKFYEQF KN+KLGIHEDS NR KL + LR+HS+ SGE+MT+LKDY++RMKE QK IYY+TG+SK  +  S F+E+  +RGFEVL+M +PIDEY +QQ+K+++ KK  C+TKEG+   E EEEKK+ EE+K A+E LCK MKD+L  KVEKV VS RL +SPC +VTS+FGWSA+ME+IM+ QALRDSS   YM +KK +EINP H ++K LK RV+AD+NDK+VKDLV LL++T+LL+SGF L+DP  +A RIHRMIKLGL
Sbjct:    2 TETFAFQAEINQLMSLIINTFYSNKEIFLRELISNSSDACDKIRYQSLTNQAVLGDESHLRIRVVPDKANKTLTVEDTGIGMTKAELVNNLGTIARSGTKAFMEALEAGGDMSMIGQFGVGFYSAYLVADRVTVVSKNNDDEAYTWESSAGGTFTVTPTPDCDLKRGTRIVLHLKEDQQEYLEERRLKDLIKKHSEFIGYDIELMVEKATEKEVTDEDEDEAAATKNEEGEEPKVEEVKDDAEEGEKKKKTKKVKEVTQEFVVQ---NKHKPLWTRDPKDVTKEEYAAFYKAISNDWEEPLSTKHFSVEGQLEFRAILFVPKRAPFDMFEPSKKRNNIKLYVRRVFIMDNCEDLCPEWLAFVRGVVDSEDLPLNISRENLQQNKILKVIRKNIVKKALELFEEIAENKEDYKKFYEQFGKNVKLGIHEDSANRKKLMELLRFHSSESGEDMTTLKDYVTRMKEGQKCIYYVTGDSKKKLETSPFIEQARRRGFEVLFMTEPIDEYVMQQVKDFEDKKFACLTKEGVHFEETEEEKKQREEEKTAYERLCKAMKDVLGDKVEKVVVSERLATSPCILVTSEFGWSAHMEQIMRNQALRDSSMSAYMMSKKTMEINPAHPIVKELKRRVEADENDKAVKDLVYLLFDTALLTSGFTLDDPTSYAERIHRMIKLGL 671

[Close]

BLAST of Heat shock protein 90 vs. UniProt/SwissProt
Match: sp|P54651|HSC90_DICDI (Heat shock cognate 90 kDa protein OS=Dictyostelium discoideum OX=44689 GN=hspD PE=1 SV=2)

HSP 1 Score: 831.247 bits (2146), Expect = 0.000e+0
Identity = 460/715 (64.34%), Postives = 563/715 (78.74%), Query Frame = 3

Query:   57 ETFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFMEALQAGA-DISMIGQFGVGFYSSYLVADKVQVISKGNDDEQYLWESSAGGSFTIKPDTSEPLGRGSKIILFMKEDQVEYLXXXXXXXXXXXHSQFIGYPIKL--VLEKERDKEVSDDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNLKLGIHEDSVNRNKLADFLRYHSTSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSVMKALKTRVDADKNDKSVKDLVMLLYETSLLSSGFALEDPQIHANRIHRMIKLGL-----GXXXXXXXXXXXXVGDVPVGPSATEDEAGKMEEVD 2177
            E F FQAEI QL+SLIINTFYSNKE+FLRELISN+SDALDKIRY+SLTD SVL++  EL IKIIPDK A TLT+ID+GIGMTK+D++ NLGTIARSGTK FME LQ+GA DISMIGQFGVGFYS+YLVAD V V SK NDDEQY+WESSAGG FTI  D +EPLGRG+KI+L MKEDQ++YL+E KIK ++KKHS+FI YPI L  + EKE D+E +                  K   E+  D + ++ +++K+KKK+K +  + + LNKTKP+WTRNP DV++E+Y  FYKS++NDWE+ LAVKHFSVEGQLEF+A+LF PK+APFDLFE+KKK NNIKLYV+RVFIMDNC D+IPEYLNFV+G+VDSEDLPLNISRE LQQNKIL VIRKNLVKKC+ELF EI E+ ++YKKFYE F+KNLKLG+HEDS NR K AD LRY ++ SG+E+ +LK+Y+ RMKE Q +IYYITGESK  V +S F+E L K+  EV+YM DPIDEY+VQQLKEYDGKKLV +TKEGL+L E E+EKKK E+ KAA E L K +KD+L  KVEKV +S RL +SPC +VTS++GWSANMERIMKAQALRDSS   YM++KK LE+NPDH +++ L  +  A +  K+ KD V LLYET+LL+SGF+L++P   A+RIHRMIKLGL          +   +TT   D+P  P    DE  +ME+VD
Sbjct:    7 ERFTFQAEINQLMSLIINTFYSNKEVFLRELISNASDALDKIRYQSLTDASVLESKTELEIKIIPDKTAKTLTLIDSGIGMTKTDMVKNLGTIARSGTKNFMEQLQSGAADISMIGQFGVGFYSAYLVADTVIVHSKNNDDEQYVWESSAGGEFTIALDHTEPLGRGTKIVLHMKEDQLDYLDETKIKNLVKKHSEFIQYPISLLTIKEKEVDEETT-----------------AKEGEEESTDAKIEEIEEEKEKKKVKVQEKEWDVLNKTKPLWTRNPSDVTKEEYNSFYKSISNDWEEPLAVKHFSVEGQLEFKAILFVPKKAPFDLFESKKKANNIKLYVKRVFIMDNCADIIPEYLNFVRGIVDSEDLPLNISRETLQQNKILTVIRKNLVKKCIELFNEIAENSEDYKKFYEAFSKNLKLGVHEDSQNREKFADLLRYQTSKSGDELVTLKEYVGRMKEGQNEIYYITGESKKAVENSPFIEGLKKKNLEVIYMCDPIDEYAVQQLKEYDGKKLVSITKEGLKLDETEDEKKKAEQDKAANEELLKQVKDVLGDKVEKVVLSTRLANSPCVLVTSEYGWSANMERIMKAQALRDSSMSSYMSSKKTLELNPDHPIVRDLAKK--AAEKSKTFKDFVYLLYETALLTSGFSLDEPSSFASRIHRMIKLGLSIQDDSSATTEESTNTTTSDDIP--PLEENDEPSEMEKVD 700

[Close]

BLAST of Heat shock protein 90 vs. TrEMBL
Match: C0KTP7 (90 kDa heat shock protein OS=Dugesia japonica OX=6161 PE=2 SV=1)

HSP 1 Score: 1144.8 bits (2960), Expect = 0.000e+0
Identity = 624/714 (87.39%), Postives = 676/714 (94.68%), Query Frame = 3

Query:   42 SMNDSETFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKGNDDEQYLWESSAGGSFTIKPDTSEPLGRGSKIILFMKEDQVEYLXXXXXXXXXXXHSQFIGYPIKLVLEKERDKEVSDDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXLNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNLKLGIHEDSVNRNKLADFLRYHSTSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSVMKALKTRVDADKNDKSVKDLVMLLYETSLLSSGFALEDPQIHANRIHRMIKLGLGXXXXXXXXXXXXVGDVPVGPSATEDEAGKMEEVD 2177
            S  D+ETFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLD+AKEL+IKIIPDKDAGTLTIIDTG+GMTK+DLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLV+DKVQVISK NDDEQ+LWESSAGGSFTI+PD+SE LGRG+KIIL+MKEDQ+EYLEERK+K+IIKKHSQFIGYPIKLVLEKERDKE+SDDEAE E K+++  E  +     +  D+E+D+ K  K KKK K K    DEEELNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKC+ELFEEIMEDK+NYKKFYEQFAKN+KLGIHEDSVNRNK+A+FLR++STSSG++++SLK+Y+SRMKENQKDIYYITGESK+NV HSAFVERLTKRG EVL M+DPIDEYSVQQLKEYDGKKLVCVTKEGLELPEDE+EK+KFEEQKAAFEPLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQ+GWSANMERIMKAQALRDSSTMGYMAAKKHLEINPD S+MK+LKTRVD+DKNDKSVKDLVMLLYETSLLSSGF LEDPQ+H NRIHRMIKLGLGI++DD+E++ TE GDVPV  S TE++AGKMEEVD
Sbjct:    2 SDTDTETFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKELMIKIIPDKDAGTLTIIDTGVGMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVSDKVQVISKSNDDEQFLWESSAGGSFTIRPDSSELLGRGTKIILYMKEDQIEYLEERKVKDIIKKHSQFIGYPIKLVLEKERDKEISDDEAEDEKKEDKEGESTEDKPKIEDLDDEEDENKKNKDKKKKKIKEKYIDEEELNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCIELFEEIMEDKENYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGDDLSSLKEYVSRMKENQKDIYYITGESKENVCHSAFVERLTKRGLEVLLMVDPIDEYSVQQLKEYDGKKLVCVTKEGLELPEDEDEKEKFEEQKAAFEPLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQYGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDRSIMKSLKTRVDSDKNDKSVKDLVMLLYETSLLSSGFTLEDPQVHGNRIHRMIKLGLGIEDDDVEMEATEAGDVPVVASTTEEDAGKMEEVD 715

[Close]

BLAST of Heat shock protein 90 vs. TrEMBL
Match: A0A3M7S7W0 (Heat shock 83 OS=Brachionus plicatilis OX=10195 GN=BpHYR1_026422 PE=3 SV=1)

HSP 1 Score: 1023.08 bits (2644), Expect = 0.000e+0
Identity = 560/712 (78.65%), Postives = 635/712 (89.19%), Query Frame = 3

Query:   51 DSETFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKGNDDEQYLWESSAGGSFTIKPDTSEPLGRGSKIILFMKEDQVEYLXXXXXXXXXXXHSQFIGYPIKLVLEKERDKEVSDDXXXXXXXXXXXXXXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXXXXXXLNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNLKLGIHEDSVNRNKLADFLRYHSTSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSVMKALKTRVDADKNDKSVKDLVMLLYETSLLSSGFALEDPQIHANRIHRMIKLGLGXXXXXXXXXXXXVGDVPVGPSATEDEAGKMEEVD 2177
            ++ETFAFQAEIAQL+SLIINTFYSNKEIFLRELISN+SDALDKIRY+SLTDP  LDT KEL IKIIPDK + TLTIIDTGIGMTK+DL+NNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYS+YLVAD+V V +K NDDEQY WESSAGGSFT++ D SEPLGRG+KI+L MKEDQ EY +E+K+KEI+KKHSQFIGYPIKLV+EKERDKE+SDDEA+ E K+E+  E E     E  +    EE + +KDKKKKKKIKEKY DEEELNKTKP+WTRNP+D+SQ +Y EFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF PKRAPFDLFENKK++N IKLYVRRVFIM+NCE+L+P+YLNF+KGVVDSEDLPLNISREMLQQ+KILKVIRKNLVKKCLEL EEI EDKDNYKKFYEQF KN+KLGIHEDS NR KL+DFLR++++SSG+EMTSLKDY++RMKENQKD+Y+ITGES++ VA SAFVE++ KRGFEV+YM+DPIDEY VQQLKEY+GKKLV VTKEGLELPEDE+EKKK E     +E LCKVMKDILDKKVEKVT+SNRLVSSPCCIVTSQ+GWSANMERIMKAQALRD+STMGYMAAKKHLEINPDHS++K+LK++VD DKNDKSVKDLV LL+ETSLLSSGF+L+ PQ HA RI RMIK+GLGIDE++ E    E    PV      +EA +MEEVD
Sbjct:   12 EAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPHKLDTCKELYIKIIPDKASNTLTIIDTGIGMTKADLVNNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSAYLVADRVVVTTKHNDDEQYTWESSAGGSFTVRLDNSEPLGRGTKIVLHMKEDQAEYNDEKKVKEIVKKHSQFIGYPIKLVVEKERDKEISDDEADEEQKQEDKTEQEQPKVEEIEEGSDKEEAETEKDKKKKKKIKEKYKDEEELNKTKPLWTRNPEDISQAEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPKRAPFDLFENKKQKNAIKLYVRRVFIMENCEELMPDYLNFIKGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELIEEISEDKDNYKKFYEQFGKNIKLGIHEDSTNRKKLSDFLRFYTSSSGDEMTSLKDYVARMKENQKDVYFITGESREVVASSAFVEKVKKRGFEVVYMVDPIDEYCVQQLKEYEGKKLVSVTKEGLELPEDEQEKKKRESDAEKYENLCKVMKDILDKKVEKVTISNRLVSSPCCIVTSQYGWSANMERIMKAQALRDTSTMGYMAAKKHLEINPDHSIIKSLKSKVDMDKNDKSVKDLVNLLFETSLLSSGFSLDHPQTHAERIFRMIKMGLGIDEEEGEQVVEEEAK-PVEDMPPLEEASRMEEVD 722

[Close]

BLAST of Heat shock protein 90 vs. TrEMBL
Match: A0A0M4HFL9 (Heat shock protein 90 OS=Macrostomum lignano OX=282301 GN=hsp90 PE=2 SV=1)

HSP 1 Score: 1019.99 bits (2636), Expect = 0.000e+0
Identity = 571/715 (79.86%), Postives = 639/715 (89.37%), Query Frame = 3

Query:   57 ETFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKGNDDEQYLWESSAGGSFTIKPDTSEPLGRGSKIILFMKEDQVEYLXXXXXXXXXXXHSQFIGYPIKLVL----EKERDKEVSDDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNLKLGIHEDSVNRNKLADFLRYHSTSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSVMKALKTRVDADKNDKSVKDLVMLLYETSLLSSGFALEDPQIHANRIHRMIKLGLGXXXXXX--XXXXXXVGDVP--VGPSATEDEAGKMEEVD 2177
            ETFAFQAEIAQL+SLIINTFYSNKEIFLRELISN+SDA+DKIRY+SLTD SVLD+ ++L IKIIP+K   +LTIID+GIGMTK+DL+NNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYS+YLVAD+V V SK NDDEQY+WESSAGGSFT++PD  EP+GRG+KI+L++KEDQ EY+EERK+KE+IKKHSQFIGYPIKLVL    EKE   + +++E E + +  E  E E     +DLDD ++D+K DKKKKKKIKEKYIDEEELNKTKPIWTRN DD++QE+Y EFYKSLTNDWE+HLAVKHFSVEGQLEFRALLF PKRAPFDLFEN+KKRNNIKLYVRRVFIMDNCE+LIPEYLNF+KGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKC+ELF++I EDK+N+KKFYEQF KNLKLGIHEDS NR KLAD+LRY+STSSG++ TSLKDY+SRMKENQKDIYYITGESK+ VAHSAFVERL KRG EVLYM DPIDEY+ QQL+EYDGKKLVCVTKEGLELPEDE+EKK FEE+KA+FEPLCKVMKDILDKKVEKV VSNRLV SPCCIVTSQ+GWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHS+   L+ R +ADKNDKSVKDLV LLYET+LLSSGFALEDPQ+HA RIHRMIKLGLGI+EDD+           +P  VG  A  D+A KMEEVD
Sbjct:    7 ETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDAIDKIRYQSLTDSSVLDSGRDLEIKIIPNKSDNSLTIIDSGIGMTKADLVNNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSAYLVADRVVVTSKHNDDEQYVWESSAGGSFTVRPDHGEPIGRGTKIVLYLKEDQTEYIEERKVKEVIKKHSQFIGYPIKLVLEKEREKEVSDDEAEEEKEEKKEDGEDAEKEKPKVEDDLDDNDEDEKGDKKKKKKIKEKYIDEEELNKTKPIWTRNQDDITQEEYGEFYKSLTNDWEEHLAVKHFSVEGQLEFRALLFVPKRAPFDLFENRKKRNNIKLYVRRVFIMDNCEELIPEYLNFIKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCMELFDDIAEDKENFKKFYEQFGKNLKLGIHEDSTNRKKLADYLRYYSTSSGDDWTSLKDYVSRMKENQKDIYYITGESKEAVAHSAFVERLRKRGLEVLYMTDPIDEYATQQLREYDGKKLVCVTKEGLELPEDEDEKKAFEEKKASFEPLCKVMKDILDKKVEKVVVSNRLVDSPCCIVTSQYGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSICGMLRQRTEADKNDKSVKDLVQLLYETALLSSGFALEDPQVHATRIHRMIKLGLGIEEDDVPDAAAGESSSSMPTEVGGDANADDA-KMEEVD 720

[Close]

BLAST of Heat shock protein 90 vs. TrEMBL
Match: A0A1C6ZXV8 (HSP90 OS=Cotesia chilonis OX=89804 GN=hsp90 PE=2 SV=1)

HSP 1 Score: 1019.61 bits (2635), Expect = 0.000e+0
Identity = 559/710 (78.73%), Postives = 638/710 (89.86%), Query Frame = 3

Query:   57 ETFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKGNDDEQYLWESSAGGSFTIKPDTSEPLGRGSKIILFMKEDQVEYLXXXXXXXXXXXHSQFIGYPIKLVLEKERDKEVSDDXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNLKLGIHEDSVNRNKLADFLRYHSTSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSVMKALKTRVDADKNDKSVKDLVMLLYETSLLSSGFALEDPQIHANRIHRMIKLGLGXXXXXXX-XXXXXVGDVPVGPSATEDEAGKMEEVD 2177
            ETFAFQAEIAQL+SLIINTFYSNKEIFLRELISNSSDALDKIRY+SLTDPS LD+ K+L IKIIP+K+  TLTIIDTGIGMTK+DL+NNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVADKV V SK NDDEQYLWES+AGGSFT++ D SEPLGRG+KI+L++KEDQ EYLEE KIKEI+KKHSQFIGYPIKLV++KER+KE+SDDEAE E + E+ E+   + K +    D+EED +K+ KKKKK IKEKY ++EELNKTKPIWTRNPDD++QE+Y EFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF P+R PFDLFENKK++NNIKLYVRRVFIMDNCE+LIPEYLNF+KGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEE+ EDK+NYKKFYEQF+KNLKLGIHEDS NR+KLAD LRYH+++SGEE  SLKDY+ RMKENQK IY+ITGESK+ VA+S+FVER+ KRGFEV+YM +PIDEY VQQ+KE+DGK+LV VTKEGLELPEDE EKKK EE KA FE LCKVMK ILD KVEKV VSNRLV SPCCIVTSQ+GW+ANMERIMKAQALRD+STMGYMAAKKHLEINPDH V++ L+ + +ADKNDKSVKDLV+LL+ET+LLSSGF+L+DPQ+HA RI+RMIKLGLGIDED+    +   + +VP   S +ED A +MEEVD
Sbjct:   13 ETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKDLSIKIIPNKNDRTLTIIDTGIGMTKADLVNNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVADKVTVTSKHNDDEQYLWESAAGGSFTVRADNSEPLGRGTKIVLYIKEDQAEYLEESKIKEIVKKHSQFIGYPIKLVVQKEREKELSDDEAEPEAETEKKEDEDDKPKIEDVGEDEEEDKEKEKKKKKKTIKEKYTEDEELNKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRMPFDLFENKKRKNNIKLYVRRVFIMDNCEELIPEYLNFMKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEELTEDKENYKKFYEQFSKNLKLGIHEDSSNRSKLADLLRYHTSASGEESCSLKDYVGRMKENQKHIYFITGESKEQVANSSFVERVKKRGFEVVYMTEPIDEYVVQQMKEFDGKQLVSVTKEGLELPEDEAEKKKREEDKAKFEELCKVMKTILDSKVEKVVVSNRLVDSPCCIVTSQYGWTANMERIMKAQALRDTSTMGYMAAKKHLEINPDHPVIENLRQKTEADKNDKSVKDLVVLLFETALLSSGFSLDDPQVHAARIYRMIKLGLGIDEDEPIGEEPKAMEEVPTLESESED-ASRMEEVD 721

[Close]

BLAST of Heat shock protein 90 vs. TrEMBL
Match: A0A267DD20 (HATPase_c domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig023254g4 PE=3 SV=1)

HSP 1 Score: 1016.91 bits (2628), Expect = 0.000e+0
Identity = 570/715 (79.72%), Postives = 639/715 (89.37%), Query Frame = 3

Query:   57 ETFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKGNDDEQYLWESSAGGSFTIKPDTSEPLGRGSKIILFMKEDQVEYLXXXXXXXXXXXHSQFIGYPIKLVL----EKERDKEVSDDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNLKLGIHEDSVNRNKLADFLRYHSTSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSVMKALKTRVDADKNDKSVKDLVMLLYETSLLSSGFALEDPQIHANRIHRMIKLGLGXXXXXX--XXXXXXVGDVP--VGPSATEDEAGKMEEVD 2177
            ETFAFQAEIAQL+SLIINTFYSNKEIFLRELISN+SDA+DKIRY+SLTD SVLD+ ++L IKIIP+K   +LTIID+GIGMTK+DL+NNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYS+YLVAD+V V SK NDDEQY+WESSAGGSFT++PD  EP+GRG+KI+L++KEDQ EY+EE+K+KE+IKKHSQFIGYPIKLVL    EKE   + +++E E + +  E  E E     +DLDD ++D+K DKKKKKKIKEKYIDEEELNKTKPIWTRN DD++QE+Y EFYKSLTNDWE+HLAVKHFSVEGQLEFRALLF PKRAPFDLFEN+KKRNNIKLYVRRVFIMDNCE+LIPEYLNF+KGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKC+ELF++I EDK+N+KKFYEQF KNLKLGIHEDS NR KLAD+LRY+STSSG++ TSLKDY+SRMKENQKDIYYITGESK+ VAHSAFVERL KRG EVLYM DPIDEY+ QQL+EYDGKKLVCVTKEGLELPEDE+EKK FEE+KA+FEPLCKVMKDILDKKVEKV VSNRLV SPCCIVTSQ+GWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHS+   L+ R +ADKNDKSVKDLV LLYET+LLSSGFALEDPQ+HA RIHRMIKLGLGI+EDD+           +P  VG  A  D+A KMEEVD
Sbjct:    7 ETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDAIDKIRYQSLTDSSVLDSGRDLEIKIIPNKSDNSLTIIDSGIGMTKADLVNNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSAYLVADRVVVTSKHNDDEQYVWESSAGGSFTVRPDHGEPIGRGTKIVLYLKEDQTEYIEEKKVKEVIKKHSQFIGYPIKLVLEKEREKEVSDDEAEEEKEEKKEDGEDAEKEKPKVEDDLDDNDEDEKGDKKKKKKIKEKYIDEEELNKTKPIWTRNQDDITQEEYGEFYKSLTNDWEEHLAVKHFSVEGQLEFRALLFVPKRAPFDLFENRKKRNNIKLYVRRVFIMDNCEELIPEYLNFIKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCMELFDDIAEDKENFKKFYEQFGKNLKLGIHEDSTNRKKLADYLRYYSTSSGDDWTSLKDYVSRMKENQKDIYYITGESKEAVAHSAFVERLRKRGLEVLYMTDPIDEYATQQLREYDGKKLVCVTKEGLELPEDEDEKKAFEEKKASFEPLCKVMKDILDKKVEKVVVSNRLVDSPCCIVTSQYGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSICGMLRQRTEADKNDKSVKDLVQLLYETALLSSGFALEDPQVHATRIHRMIKLGLGIEEDDVPDAAAGESSSSMPTEVGGDANADDA-KMEEVD 720

[Close]

BLAST of Heat shock protein 90 vs. Ensembl Cavefish
Match: hsp90aa1.2 (Astyanax mexicanus heat shock protein HSP 90-alpha 1-like (LOC103024454), mRNA. [Source:RefSeq mRNA;Acc:NM_001291257])

HSP 1 Score: 665.996 bits (1717), Expect = 0.000e+0
Identity = 343/445 (77.08%), Postives = 392/445 (88.09%), Query Frame = 3

Query:  852 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNLKLGIHEDSVNRNKLADFLRYHSTSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSVMKALKTRVDADKNDKSVKDLVMLLYETSLLSSGFALEDPQIHANRIHRMIKLGLGX---XXXXXXXXXXXVGDVPVGPSATEDEAGKMEEVD 2177
            LNKTKPIWTRNPDD++ E+Y EFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF P+RA FDLFENKKKRNNIKLYVRRVFIMDNCE+L+PEYLNF+KGVVDSEDLPLNISREMLQQ+KILKVIRKNLVKKCLELF EI EDKDNYKK YEQF+KN+KLGIHEDS NR KL++ LRY++++SG+EM SLKDY+SRMK++QK IYYITGE+KD VA+SAFVERL K G EV+YMI+PIDEY VQQLKEYDGK L+ VTKEGLELPEDEEEKKK +E K  FE LCK+MKDILDKK+EKVTVSNRLV+SPCCIVTS +GW+ANMERIMK+QALRD+STMGYM AKKHLEINP H +++ L+ + +ADKNDK+VKDLV+LL+ET+LLSSGF LEDPQ HANRI+RMIKLGLGI   D    +I      D+PV     +D+  +MEEVD
Sbjct:  281 LNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAAFDLFENKKKRNNIKLYVRRVFIMDNCEELMPEYLNFMKGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTEISEDKDNYKKLYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSNSGDEMVSLKDYVSRMKDSQKHIYYITGETKDQVANSAFVERLRKAGLEVIYMIEPIDEYCVQQLKEYDGKNLLSVTKEGLELPEDEEEKKKQDELKTKFENLCKIMKDILDKKIEKVTVSNRLVASPCCIVTSTYGWTANMERIMKSQALRDNSTMGYMTAKKHLEINPLHPIVETLREKAEADKNDKAVKDLVILLFETALLSSGFTLEDPQTHANRIYRMIKLGLGIDDDDSAVEDILQPTEEDMPVLEG--DDDTSRMEEVD 723

HSP 2 Score: 337.806 bits (865), Expect = 1.089e-104
Identity = 170/215 (79.07%), Postives = 197/215 (91.63%), Query Frame = 3

Query:   51 DSETFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKGNDDEQYLWESSAGGSFTIKPDTSEPLGRGSKIILFMKEDQVEYLXXXXXXXXXXXHSQFIGYPIKLVLEKERDKEV 695
            D ETFAFQAEIAQL+SLIINTFYSNKEIFLRELISNSSDALDKIRY+SLTDPS L++ K+L I++IPD    TLTIIDTGIGMTK+DLINNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVA++V VI+K NDDEQY+WES+AGGSFT+KPD  E +GRG+K+IL +KEDQ EY EE++IKE++KKHSQFIGYPI L +EK+R+KEV
Sbjct:   13 DVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLESCKDLKIELIPDLKNRTLTIIDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAERVTVITKHNDDEQYVWESAAGGSFTVKPDNGESIGRGTKVILHLKEDQSEYTEEKRIKEVVKKHSQFIGYPITLFVEKQREKEV 227

[Close]

Query:  852 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNLKLGIHEDSVNRNKLADFLRYHSTSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSVMKALKTRVDADKNDKSVKDLVMLLYETSLLSSGFALEDPQIHANRIHRMIKLGLGX---XXXXXXXXXXXVGDVPVGPSATEDEAGKMEEVD 2177
            LNKTKPIWTRNPDD++ E+Y EFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF P+RA FDLFENKKKRNNIKLYVRRVFIMDNCE+L+PEYLNF+KGVVDSEDLPLNISREMLQQ+KILKVIRKNLVKKCLELF EI EDKDNYKK YEQF+KN+KLGIHEDS NR KL++ LRY++++SG+EM SLKDY+SRMK++QK IYYITGE+KD VA+SAFVERL K G EV+YMI+PIDEY VQQLKEYDGK L+ VTKEGLELPEDEEEKKK +E K  FE LCK+MKDILDKK+EKVTVSNRLV+SPCCIVTS +GW+ANMERIMK+QALRD+STMGYM AKKHLEINP H +++ L+ + +ADKNDK+VKDLV+LL+ET+LLSSGF LEDPQ HANRI+RMIKLGLGI   D    +I      D+PV     +D+  +MEEVD
Sbjct:  281 LNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAAFDLFENKKKRNNIKLYVRRVFIMDNCEELMPEYLNFMKGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTEISEDKDNYKKLYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSNSGDEMVSLKDYVSRMKDSQKHIYYITGETKDQVANSAFVERLRKAGLEVIYMIEPIDEYCVQQLKEYDGKNLLSVTKEGLELPEDEEEKKKQDELKTKFENLCKIMKDILDKKIEKVTVSNRLVASPCCIVTSTYGWTANMERIMKSQALRDNSTMGYMTAKKHLEINPLHPIVETLREKAEADKNDKAVKDLVILLFETALLSSGFTLEDPQTHANRIYRMIKLGLGIDDDDSAVEDILQPTEEDMPVLEG--DDDTSRMEEVD 723

HSP 2 Score: 337.806 bits (865), Expect = 1.089e-104
Identity = 170/215 (79.07%), Postives = 197/215 (91.63%), Query Frame = 3

Query:   51 DSETFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKGNDDEQYLWESSAGGSFTIKPDTSEPLGRGSKIILFMKEDQVEYLXXXXXXXXXXXHSQFIGYPIKLVLEKERDKEV 695
            D ETFAFQAEIAQL+SLIINTFYSNKEIFLRELISNSSDALDKIRY+SLTDPS L++ K+L I++IPD    TLTIIDTGIGMTK+DLINNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVA++V VI+K NDDEQY+WES+AGGSFT+KPD  E +GRG+K+IL +KEDQ EY EE++IKE++KKHSQFIGYPI L +EK+R+KEV
Sbjct:   13 DVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLESCKDLKIELIPDLKNRTLTIIDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAERVTVITKHNDDEQYVWESAAGGSFTVKPDNGESIGRGTKVILHLKEDQSEYTEEKRIKEVVKKHSQFIGYPITLFVEKQREKEV 227

[Close]

BLAST of Heat shock protein 90 vs. Ensembl Cavefish
Match: hsp90ab1 (heat shock protein 90 alpha family class B member 1 [Source:NCBI gene;Acc:103047517])

HSP 1 Score: 665.226 bits (1715), Expect = 0.000e+0
Identity = 349/444 (78.60%), Postives = 399/444 (89.86%), Query Frame = 3

Query:  852 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNLKLGIHEDSVNRNKLADFLRYHSTSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSVMKALKTRVDADKNDKSVKDLVMLLYETSLLSSGFALEDPQIHANRIHRMIKLGLGXXXXXXXXXXXXVGDVP--VGPSATEDEAGKMEEVD 2177
            LNKTKPIWTRNPDD++ E+Y EFYKSLTNDWEDHLA+KHFSVEGQLEFRALLF P+RAPFDLFENKKK+NNIKLYVRRVFIMD+CE+LIPEYLNF++GVVDSEDLPLNISREMLQQ+KILKVIRKN+VKKCLELF E+ EDKDNYKKFYE F+KN+KLGIHEDS NR KL++ LRYHS+ SG+EMTSL +YLSRMKENQK IYYITGESKD VA+SAFVER+ KRGFEVLYM +PIDEY VQQLKE+DGK LV VTKEGLELPEDEEEKKK E+ KA FE LCK+MK+ILDKKVEKVTVSNRLVSSPCCIVTS +GW+ANMERIMKAQALRD+STMGYM AKKHLEINPDH +M+ L+ + +ADKNDK+VKDLV+LL+ET+LLSSGF+L+DPQ H+NRI+RMIKLGLGID+DD+  +       P  + P   +D+A +MEEVD
Sbjct:  282 LNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAIKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRVFIMDSCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFAELAEDKDNYKKFYESFSKNIKLGIHEDSQNRKKLSELLRYHSSQSGDEMTSLSEYLSRMKENQKSIYYITGESKDQVANSAFVERVRKRGFEVLYMTEPIDEYCVQQLKEFDGKTLVSVTKEGLELPEDEEEKKKMEDDKAKFENLCKLMKEILDKKVEKVTVSNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIMETLRQKAEADKNDKAVKDLVILLFETALLSSGFSLDDPQTHSNRIYRMIKLGLGIDDDDIPSEEPTSAPAPEEIPPLEGDDDASRMEEVD 725

HSP 2 Score: 338.191 bits (866), Expect = 1.009e-104
Identity = 169/213 (79.34%), Postives = 196/213 (92.02%), Query Frame = 3

Query:   60 TFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKGNDDEQYLWESSAGGSFTIKPDTSEPLGRGSKIILFMKEDQVEYLXXXXXXXXXXXHSQFIGYPIKLVLEKERDKEVS 698
            TFAFQAEIAQL+SLIINTFYSNKEIFLRELISN+SDALDKIRY+SLTDPS LD+ K+L I IIP+K   TLT++DTGIGMTK+DLINNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVA+KV VI+K NDDEQY WESSAGGSFT+K D  EP+GRG+K+IL +KEDQ EY+E++++KE++KKHSQFIGYPI L +EKERDKE+S
Sbjct:   13 TFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKDLKIDIIPNKLERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVKVDNGEPIGRGTKVILHLKEDQTEYIEDKRVKEVVKKHSQFIGYPITLYVEKERDKEIS 225

[Close]

BLAST of Heat shock protein 90 vs. Ensembl Cavefish
Match: hsp90aa1.2 (Astyanax mexicanus heat shock protein HSP 90-alpha 1-like (LOC103024454), mRNA. [Source:RefSeq mRNA;Acc:NM_001291257])

HSP 1 Score: 655.981 bits (1691), Expect = 0.000e+0
Identity = 345/445 (77.53%), Postives = 399/445 (89.66%), Query Frame = 3

Query:  852 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNLKLGIHEDSVNRNKLADFLRYHSTSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSVMKALKTRVDADKNDKSVKDLVMLLYETSLLSSGFALEDPQIHANRIHRMIKLGLGXXX---XXXXXXXXXVGDVPVGPSATEDEAGKMEEVD 2177
            LNKTKP+WTRNPDD++ E+Y EFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF P+RAPFDLFENKKK+NNIKLYVRRVFIMDNC++LIPEYLNF++GVVDSEDLPLNISREMLQQ+KILKVIRKNLVKKCLELF E+ EDKDNYKKFYEQF+KN+KLGIHEDS NR KL++ LRY++++SG+EM SLKDY++RMK+ QK IYYITGE+KD VA+SAFVERL K G EV+YMI+PIDEY VQQLKE++GK LV VTKEGLELPEDEEEKKK EE+KA FE LCK+MKDIL+KKVEKVTVSNRLVSSPCCIVTS +GW+ANMERIMKAQALRD+STMGYMAAKKHLEINPDH +++ L+ + +ADKNDKSVKDLV+LL+ET+LLSSGF L+DPQ H+NRI+RMIKLGLGIDE      E  +  + D+P  P   +D+  +MEEVD
Sbjct:  289 LNKTKPLWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENKKKKNNIKLYVRRVFIMDNCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKDNYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYVTRMKDTQKHIYYITGETKDQVANSAFVERLRKAGLEVIYMIEPIDEYCVQQLKEFEGKNLVSVTKEGLELPEDEEEKKKQEEKKAQFENLCKIMKDILEKKVEKVTVSNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHPIIETLRQKAEADKNDKSVKDLVILLFETALLSSGFTLDDPQTHSNRIYRMIKLGLGIDEDDLSTEEPSSAPIEDMP--PLEGDDDTSRMEEVD 731

HSP 2 Score: 345.895 bits (886), Expect = 1.334e-107
Identity = 178/216 (82.41%), Postives = 200/216 (92.59%), Query Frame = 3

Query:   51 DSETFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKGNDDEQYLWESSAGGSFTIKPDTSEPLGRGSKIILFMKEDQVEYLXXXXXXXXXXXHSQFIGYPIKLVLEKERDKEVS 698
            D ETFAFQAEIAQL+SLIINTFYSNKEIFLRELISNSSDALDKIRY+SLT+PS LD+ K+L I+IIP+K+  TLTIIDTGIGMTK+DLINNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVA+KV VI+K NDDEQY WESSAGGSFT+K D SEP+ RG+K+IL +KEDQ EY+EER+IKEI+KKHSQFIGYPI L +EKERDKEVS
Sbjct:   13 DVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTEPSKLDSGKDLKIEIIPNKEERTLTIIDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVKVDNSEPVNRGTKVILHLKEDQTEYIEERRIKEIVKKHSQFIGYPITLYVEKERDKEVS 228

[Close]

BLAST of Heat shock protein 90 vs. Ensembl Cavefish
Match: hsp90aa1.2 (Astyanax mexicanus heat shock protein HSP 90-alpha 1-like (LOC103024454), mRNA. [Source:RefSeq mRNA;Acc:NM_001291257])

HSP 1 Score: 655.21 bits (1689), Expect = 0.000e+0
Identity = 345/445 (77.53%), Postives = 399/445 (89.66%), Query Frame = 3

Query:  852 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNLKLGIHEDSVNRNKLADFLRYHSTSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSVMKALKTRVDADKNDKSVKDLVMLLYETSLLSSGFALEDPQIHANRIHRMIKLGLGXXX---XXXXXXXXXVGDVPVGPSATEDEAGKMEEVD 2177
            LNKTKP+WTRNPDD++ E+Y EFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF P+RAPFDLFENKKK+NNIKLYVRRVFIMDNC++LIPEYLNF++GVVDSEDLPLNISREMLQQ+KILKVIRKNLVKKCLELF E+ EDKDNYKKFYEQF+KN+KLGIHEDS NR KL++ LRY++++SG+EM SLKDY++RMK+ QK IYYITGE+KD VA+SAFVERL K G EV+YMI+PIDEY VQQLKE++GK LV VTKEGLELPEDEEEKKK EE+KA FE LCK+MKDIL+KKVEKVTVSNRLVSSPCCIVTS +GW+ANMERIMKAQALRD+STMGYMAAKKHLEINPDH +++ L+ + +ADKNDKSVKDLV+LL+ET+LLSSGF L+DPQ H+NRI+RMIKLGLGIDE      E  +  + D+P  P   +D+  +MEEVD
Sbjct:  288 LNKTKPLWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENKKKKNNIKLYVRRVFIMDNCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKDNYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYVTRMKDTQKHIYYITGETKDQVANSAFVERLRKAGLEVIYMIEPIDEYCVQQLKEFEGKNLVSVTKEGLELPEDEEEKKKQEEKKAQFENLCKIMKDILEKKVEKVTVSNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHPIIETLRQKAEADKNDKSVKDLVILLFETALLSSGFTLDDPQTHSNRIYRMIKLGLGIDEDDLSTEEPSSAPIEDMP--PLEGDDDTSRMEEVD 730

HSP 2 Score: 345.125 bits (884), Expect = 2.133e-107
Identity = 177/217 (81.57%), Postives = 202/217 (93.09%), Query Frame = 3

Query:   48 NDSETFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKGNDDEQYLWESSAGGSFTIKPDTSEPLGRGSKIILFMKEDQVEYLXXXXXXXXXXXHSQFIGYPIKLVLEKERDKEVS 698
            +++ETFAFQAEIAQL+SLIINTFYSNKEIFLRELISNSSDALDKIRY+SLT+PS LD+ K+L I+IIP+K+  TLTIIDTGIGMTK+DLINNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVA+KV VI+K NDDEQY WESSAGGSFT+K D SEP+ RG+K+IL +KEDQ EY+EER+IKEI+KKHSQFIGYPI L +EKERDKEVS
Sbjct:   11 DEAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTEPSKLDSGKDLKIEIIPNKEERTLTIIDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVKVDNSEPVNRGTKVILHLKEDQTEYIEERRIKEIVKKHSQFIGYPITLYVEKERDKEVS 227

[Close]

BLAST of Heat shock protein 90 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003399.1 (pep scaffold:Pmarinus_7.0:GL479675:6143:15195:1 gene:ENSPMAG00000002912.1 transcript:ENSPMAT00000003399.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 649.047 bits (1673), Expect = 0.000e+0
Identity = 339/442 (76.70%), Postives = 397/442 (89.82%), Query Frame = 3

Query:  852 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNLKLGIHEDSVNRNKLADFLRYHSTSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSVMKALKTRVDADKNDKSVKDLVMLLYETSLLSSGFALEDPQIHANRIHRMIKLGLGXXXXXXXXXXXXVGDVPVGPSATEDEAGKMEEVD 2177
            LNKTKP+WTRNPDD+SQE+Y EFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF P+RAPFDLFENKKK+NNIKLYVRRVFIMDNCEDLIPEYLNF+KGVVDSEDLPLNISREMLQQ+KILKVIRKN+VKKC+ELF  + EDK+NYKKFYEQF+KN+KLGIHEDS NR +L++ LRYH++ +GE++ SLK+Y+SRMKENQK IYYITGESK+ V++SAFVER+ KRG EV+YM +PIDEY VQQLKE+DGK LV VTKEGLELPEDE+EKKK EE KA +E LCKV+K+ILDKKVEKVTVSNRLV+SPCCIVTS +GW+ANMERIMKAQALRDSSTMGYMAAKKHLEINP+H +++ L+ + +ADKNDKSVKDL++LL+ET+LLSSGF+L+DPQ H+NRI+RMIKLGLGID+D+   D +        P    ++A +MEEVD
Sbjct:  260 LNKTKPLWTRNPDDISQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENKKKKNNIKLYVRRVFIMDNCEDLIPEYLNFIKGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCMELFTGLAEDKENYKKFYEQFSKNMKLGIHEDSQNRKRLSEMLRYHTSVTGEDVCSLKEYVSRMKENQKHIYYITGESKEQVSNSAFVERVRKRGLEVVYMTEPIDEYCVQQLKEFDGKTLVSVTKEGLELPEDEDEKKKQEEAKAKYENLCKVVKEILDKKVEKVTVSNRLVASPCCIVTSTYGWTANMERIMKAQALRDSSTMGYMAAKKHLEINPEHPIVETLRQKAEADKNDKSVKDLIILLFETALLSSGFSLDDPQTHSNRIYRMIKLGLGIDDDEPIPDESTPTVTEEMPPLEGEDASRMEEVD 701

HSP 2 Score: 279.256 bits (713), Expect = 1.604e-83
Identity = 147/218 (67.43%), Postives = 174/218 (79.82%), Query Frame = 3

Query:   51 DSETFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKGNDDEQYLWESSAGGSFTIKPDTSEPLGRGSKIILFMKEDQVEYLXXXXXXXXXXXHSQFIGYPIKLVLEKERDKEVSDD 704
            ++ETFAFQAEIAQL+SLIINTFYSNKEIFLRELISNSSDALDKIRY+SLTDPS +D+ KEL I +IP+++  T                            AFMEALQAGADISMIGQFGVGFYS+YL+A++V V++K NDDEQYLWESSAGGSFT++ D  E +GRG+KI+L +KEDQ EYLEE++IK+I+KKHSQFIGYPI L +EKERDKEVSDD
Sbjct:   13 ETETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKMDSGKELKIDVIPNRNERT----------------------------AFMEALQAGADISMIGQFGVGFYSAYLIAERVSVVTKHNDDEQYLWESSAGGSFTVRLDNGESIGRGTKIVLHLKEDQSEYLEEKRIKDIVKKHSQFIGYPITLFVEKERDKEVSDD 202

[Close]

BLAST of Heat shock protein 90 vs. Ensembl Sea Lamprey
Match: hsp90b1 (heat shock protein 90, beta (grp94), member 1 [Source:ZFIN;Acc:ZDB-GENE-031002-1])

HSP 1 Score: 337.421 bits (864), Expect = 1.458e-104
Identity = 182/413 (44.07%), Postives = 269/413 (65.13%), Query Frame = 3

Query:  852 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFE--NKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNLKLGIHEDSVNRNKLADFLRYHSTSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQ-LKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQAL---RDSSTMGYMAAKKHLEINPDHSVMKALKTRVDADKNDKSVKDLVMLLYETSLLSSGFALEDPQIHANRIHRMIKLGL 2072
            +N  KPIW R   +V  ++Y  FYKS + D ++ L   HF+ EG++ FR++LF P  AP  +F+    KK + IK+YVRRVFI D+  D++P+YLNFVKGVVDS+DLPLN+SRE LQQ+K+LKVI+K LV+K L++ ++I  D+   +KF+++F  N+KLG+ ED  NR +LA  LR+ S+   +++TSL++Y+ RMKE Q  IY+I G ++  V  S FVERL K+G+EVL++ + +DEY +Q  L ++       +      L             +  F  LC        +++EK TVS RL+ SPC +V SQ+GWS NMERIMKAQA    +D+++  Y + KK  EINP H ++K L TRV A + D + KDL ++L+ET+ L SG+ L+D +  ++RI RM+++ L
Sbjct:  313 MNDIKPIWQRVTKEVEDDEYKAFYKSFSKDSDEPLTWIHFTAEGEVTFRSILFVPTSAPRGMFDEYGTKKTDFIKMYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIKKKLVRKTLDMIKKIA-DESYQEKFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSYGTDKLTSLEEYVERMKEKQDKIYFIAGANRKEVESSPFVERLLKKGYEVLFLTEAVDEYCIQSDLGQFMDLYASILITAWSRLGPSLRVYAARFAVQRGFPLLCT-------RQIEKATVSQRLLGSPCALVASQYGWSGNMERIMKAQAYQTGKDAASNFYGSQKKTFEINPRHPLIKELLTRVQASEEDATAKDLALVLFETATLRSGYLLQDTRSFSDRIERMLRVSL 717

HSP 2 Score: 154.066 bits (388), Expect = 3.902e-39
Identity = 94/203 (46.31%), Postives = 127/203 (62.56%), Query Frame = 3

Query:   54 SETFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKGNDDEQYLWESSAGGSFTIKPDT-SEPLGRGSKIILFMKEDQVEYLXXXXXXXXXXXHSQFIGYPI 659
            +E   FQAE+ +++ LIIN+ Y NKEIFLRELISN+SDALDKIR  SLTD   LD   EL IKI  DK+   L I      ++++     L T  +S ++             +IGQFGVGFYS++LVAD++ V SK N+D Q++WES +   FT+  D     L RG+ I L +KE+  +YLE   IK ++KK+SQFI +PI
Sbjct:   75 AEKHVFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLMSLTDGKALDATDELTIKIKADKEKNLLHIF-----LSRA---QELATEGQSTSE-------------LIGQFGVGFYSAFLVADRIVVTSKHNNDTQHIWESDS-SEFTVTEDPRGNTLARGTTITLVLKEEAADYLELETIKNLVKKYSQFINFPI 255

[Close]

BLAST of Heat shock protein 90 vs. Ensembl Sea Lamprey
Match: hsp90ab1 (heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2 [Source:ZFIN;Acc:ZDB-GENE-031001-3])

HSP 1 Score: 212.616 bits (540), Expect = 2.340e-63
Identity = 120/183 (65.57%), Postives = 138/183 (75.41%), Query Frame = 3

Query:  159 SSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKGNDDEQYLWESSAGGSFTIKPDT-SEPLGRGSKIILFMKEDQVEYLXXXXXXXXXXXHSQFIGYPIKLVLEKERDKEVSDD 704
            S+ ALDKIRY+SLTDPS LDT KEL I IIP+K   TLT                           FMEALQAGADISMIGQFGVGFYS+YLVA++V V++K NDDEQY+WESSAGGSFT++PD   EPLGRG+KI+L +KEDQ EYLEER IK+I+KKHSQFIGYPI L +EKER+KEVSDD
Sbjct:    1 SAQALDKIRYESLTDPSKLDTGKELKIDIIPNKIDRTLT---------------------------FMEALQAGADISMIGQFGVGFYSAYLVAERVTVVTKHNDDEQYVWESSAGGSFTVRPDNDGEPLGRGTKIVLHIKEDQTEYLEERSIKDIVKKHSQFIGYPITLYVEKERNKEVSDD 156

HSP 2 Score: 134.035 bits (336), Expect = 3.652e-35
Identity = 67/77 (87.01%), Postives = 73/77 (94.81%), Query Frame = 3

Query:  852 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVR 1082
            LNKTKP+WTRNPDD++ E+Y EFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF P+RA FDLFENKKK+NNIKLYVR
Sbjct:  214 LNKTKPLWTRNPDDITAEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAAFDLFENKKKKNNIKLYVR 290

[Close]

BLAST of Heat shock protein 90 vs. Ensembl Yeast
Match: HSP82 (Hsp90 chaperone; redundant in function with Hsc82p; required for pheromone signaling, negative regulation of Hsf1p; docks with Tom70p for mitochondrial preprotein delivery; promotes telomerase DNA binding, nucleotide addition; protein abundance increases in response to DNA replication stress; contains two acid-rich unstructured regions that promote solubility of chaperone-substrate complexes; HSP82 has a paralog, HSC82, that arose from the whole genome duplication [Source:SGD;Acc:S000006161])

HSP 1 Score: 780.4 bits (2014), Expect = 0.000e+0
Identity = 429/676 (63.46%), Postives = 542/676 (80.18%), Query Frame = 3

Query:   54 SETFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKGNDDEQYLWESSAGGSFTIKPD-TSEPLGRGSKIILFMKEDQVEYLXXXXXXXXXXXHSQFIGYPIKLVLEKERDKEVSDDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNLKLGIHEDSVNRNKLADFLRYHSTSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSVMKALKTRVD-ADKNDKSVKDLVMLLYETSLLSSGFALEDPQIHANRIHRMIKLGLG 2075
            SETF FQAEI QL+SLIINT YSNKEIFLRELISN+SDALDKIRYKSL+DP  L+T  +L I+I P  +   L I D+GIGMTK++LINNLGTIA+SGTKAFMEAL AGAD+SMIGQFGVGFYS +LVAD+VQVISK NDDEQY+WES+AGGSFT+  D  +E +GRG+ + LF+K+DQ+EYLEE++IKE+IK+HS+F+ YPI+LV+ KE +KEV   E E + ++++ EE +D+   +   +E D++++ K K KK+KE+  + EELNKTKP+WTRNP D++QE+Y  FYKS++NDWED L VKHFSVEGQLEFRA+LF PKRAPFDLFE+KKK+NNIKLYVRRVFI D  EDLIPE+L+FVKGVVDSEDLPLN+SREMLQQNKI+KVIRKN+VKK +E F EI ED + ++KFY  F+KN+KLG+HED+ NR  LA  LRY+ST S +E+TSL DY++RM E+QK+IYYITGES   V  S F++ L  + FEVL++ DPIDEY+  QLKE++GK LV +T +  EL E +EEK + E++   +EPL K +K+IL  +VEKV VS +L+ +P  I T QFGWSANMERIMKAQALRDSS   YM++KK  EI+P   ++K LK RVD     DK+VKDL  LLYET+LL+SGF+L++P   A+RI+R+I LGL 
Sbjct:    3 SETFEFQAEITQLMSLIINTVYSNKEIFLRELISNASDALDKIRYKSLSDPKQLETEPDLFIRITPKPEQKVLEIRDSGIGMTKAELINNLGTIAKSGTKAFMEALSAGADVSMIGQFGVGFYSLFLVADRVQVISKSNDDEQYIWESNAGGSFTVTLDEVNERIGRGTILRLFLKDDQLEYLEEKRIKEVIKRHSEFVAYPIQLVVTKEVEKEVPIPEEEKKDEEKKDEEKKDEDDKKPKLEEVDEEEEKKPKTKKVKEEVQEIEELNKTKPLWTRNPSDITQEEYNAFYKSISNDWEDPLYVKHFSVEGQLEFRAILFIPKRAPFDLFESKKKKNNIKLYVRRVFITDEAEDLIPEWLSFVKGVVDSEDLPLNLSREMLQQNKIMKVIRKNIVKKLIEAFNEIAEDSEQFEKFYSAFSKNIKLGVHEDTQNRAALAKLLRYNSTKSVDELTSLTDYVTRMPEHQKNIYYITGESLKAVEKSPFLDALKAKNFEVLFLTDPIDEYAFTQLKEFEGKTLVDIT-KDFELEETDEEKAEREKEIKEYEPLTKALKEILGDQVEKVVVSYKLLDAPAAIRTGQFGWSANMERIMKAQALRDSSMSSYMSSKKTFEISPKSPIIKELKKRVDEGGAQDKTVKDLTKLLYETALLTSGFSLDEPTSFASRINRLISLGLN 677

[Close]

BLAST of Heat shock protein 90 vs. Ensembl Yeast
Match: HSC82 (Cytoplasmic chaperone of the Hsp90 family; plays a role in determining prion variants; redundant in function and nearly identical with Hsp82p, and together they are essential; expressed constitutively at 10-fold higher basal levels than HSP82 and induced 2-3 fold by heat shock; contains two acid-rich unstructured regions that promote the solubility of chaperone-substrate complexes; HSC82 has a paralog, HSP82, that arose from the whole genome duplication [Source:SGD;Acc:S000004798])

HSP 1 Score: 768.844 bits (1984), Expect = 0.000e+0
Identity = 437/712 (61.38%), Postives = 555/712 (77.95%), Query Frame = 3

Query:   57 ETFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKGNDDEQYLWESSAGGSFTIKPD-TSEPLGRGSKIILFMKEDQVEYLXXXXXXXXXXXHSQFIGYPIKLVLEKERDKEVSDDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNLKLGIHEDSVNRNKLADFLRYHSTSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSVMKALKTRVD-ADKNDKSVKDLVMLLYETSLLSSGFALEDPQIHANRIHRMIKLGLGXXXXXXXXXXXXVG-DVPVG--PSATEDEAGKMEEVD 2177
            ETF FQAEI QL+SLIINT YSNKEIFLRELISN+SDALDKIRY++L+DP  L+T  +L I+I P  +   L I D+GIGMTK++LINNLGTIA+SGTKAFMEAL AGAD+SMIGQFGVGFYS +LVAD+VQVISK N+DEQY+WES+AGGSFT+  D  +E +GRG+ + LF+K+DQ+EYLEE++IKE+IK+HS+F+ YPI+L++     KEV  +    E +K++ E+ ++  K   L++ ++++++ K K KK+KE+  + EELNKTKP+WTRNP D++QE+Y  FYKS++NDWED L VKHFSVEGQLEFRA+LF PKRAPFDLFE+KKK+NNIKLYVRRVFI D  EDLIPE+L+FVKGVVDSEDLPLN+SREMLQQNKI+KVIRKN+VKK +E F EI ED + + KFY  FAKN+KLG+HED+ NR  LA  LRY+ST S +E+TSL DY++RM E+QK+IYYITGES   V  S F++ L  + FEVL++ DPIDEY+  QLKE++GK LV +T +  EL E +EEK + E++   +EPL K +KDIL  +VEKV VS +L+ +P  I T QFGWSANMERIMKAQALRDSS   YM++KK  EI+P   ++K LK RVD     DK+VKDL  LL+ET+LL+SGF+LE+P   A+RI+R+I LGL IDED+      E   + PV   P+ TE     MEEVD
Sbjct:    4 ETFEFQAEITQLMSLIINTVYSNKEIFLRELISNASDALDKIRYQALSDPKQLETEPDLFIRITPKPEEKVLEIRDSGIGMTKAELINNLGTIAKSGTKAFMEALSAGADVSMIGQFGVGFYSLFLVADRVQVISKNNEDEQYIWESNAGGSFTVTLDEVNERIGRGTVLRLFLKDDQLEYLEEKRIKEVIKRHSEFVAYPIQLLV----TKEVEKEVPIPEEEKKDEEKKDEDDKKPKLEEVDEEEEEKKPKTKKVKEEVQELEELNKTKPLWTRNPSDITQEEYNAFYKSISNDWEDPLYVKHFSVEGQLEFRAILFIPKRAPFDLFESKKKKNNIKLYVRRVFITDEAEDLIPEWLSFVKGVVDSEDLPLNLSREMLQQNKIMKVIRKNIVKKLIEAFNEIAEDSEQFDKFYSAFAKNIKLGVHEDTQNRAALAKLLRYNSTKSVDELTSLTDYVTRMPEHQKNIYYITGESLKAVEKSPFLDALKAKNFEVLFLTDPIDEYAFTQLKEFEGKTLVDIT-KDFELEETDEEKAEREKEIKEYEPLTKALKDILGDQVEKVVVSYKLLDAPAAIRTGQFGWSANMERIMKAQALRDSSMSSYMSSKKTFEISPKSPIIKELKKRVDEGGAQDKTVKDLTNLLFETALLTSGFSLEEPTSFASRINRLISLGLNIDEDEETETAPEASTEAPVEEVPADTE-----MEEVD 705

[Close]

BLAST of Heat shock protein 90 vs. Ensembl Nematostella
Match: HSP90 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RJ66])

HSP 1 Score: 683.715 bits (1763), Expect = 0.000e+0
Identity = 354/444 (79.73%), Postives = 399/444 (89.86%), Query Frame = 3

Query:  852 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNLKLGIHEDSVNRNKLADFLRYHSTSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSVMKALKTRVDADKNDKSVKDLVMLLYETSLLSSGFALEDPQIHANRIHRMIKLGLGXXXXXXXXXXXXVGD--VPVGPSATEDEAGKMEEVD 2177
            LNKTKPIW RN D+++ E+Y EFYKSLTNDWE+HLAVKHFSVEGQLEFRALLF PKRAPFDLFE++KKRNNIKLYVRRVFIMDNCEDLIPEYL F+KGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKC+ELF EI ED+DNYKKFYEQF KNLKLGIHEDSVNR KLAD LRYHS+SSG+E+TSLKDY++RMKENQKDIY+ITGESKD V+HSAFVER+  RGFEVLYM++PIDEY++QQLKEYDGKKLV VTKEGLELPEDE+EKK  EE+ A +E LCKV+KDILDKK+EKV VS+RLVSSPCCIVTSQFGW+ANMERIMKAQALRD+STMGYMAAKKHLEINPDH++M +L+ +V+ADKNDKS+KDLVMLLYETSLL+SGF LEDPQ+H+ RI+RMI LGLGIDE+        V +   P+      D+A KMEEVD
Sbjct:  284 LNKTKPIWMRNADEITTEEYGEFYKSLTNDWEEHLAVKHFSVEGQLEFRALLFVPKRAPFDLFESRKKRNNIKLYVRRVFIMDNCEDLIPEYLGFIKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCMELFNEIAEDQDNYKKFYEQFGKNLKLGIHEDSVNRAKLADLLRYHSSSSGDELTSLKDYVTRMKENQKDIYFITGESKDQVSHSAFVERVKSRGFEVLYMVEPIDEYAIQQLKEYDGKKLVSVTKEGLELPEDEDEKKAREEKVAKYEGLCKVIKDILDKKIEKVVVSSRLVSSPCCIVTSQFGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHAIMDSLRKKVEADKNDKSLKDLVMLLYETSLLTSGFTLEDPQVHSGRIYRMIGLGLGIDEEPEAEGADAVTEDMPPLEGDDANDDASKMEEVD 727

HSP 2 Score: 334.724 bits (857), Expect = 6.368e-104
Identity = 167/216 (77.31%), Postives = 197/216 (91.20%), Query Frame = 3

Query:   36 MESMNDSETFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKGNDDEQYLWESSAGGSFTIKPDTSEPLGRGSKIILFMKEDQVEYLXXXXXXXXXXXHSQFIGYPIKLVLEKER 683
            ME   D ETFAFQAEIAQL+SLIINTFYSNKEIFLRELISNSSDALDKIRY SLTDPSVLD+ K+L I +IP+K+  +LTI D+G+GMTK+DL+NNLGTIA+SGTK FMEALQAGADISMIGQFGVGFYS+YLVA+KV V +K NDDEQY+WES+AGGSFT+K D+ EPLGRG+KI+L++KEDQ EYLEE++IKEI+KKHSQFIGYP+ L+++KER
Sbjct:   10 MEEDQDVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYLSLTDPSVLDSCKDLKITLIPNKEENSLTIQDSGVGMTKADLVNNLGTIAKSGTKTFMEALQAGADISMIGQFGVGFYSAYLVAEKVVVTTKHNDDEQYIWESAAGGSFTVKRDSGEPLGRGTKIVLYLKEDQTEYLEEKRIKEIVKKHSQFIGYPLSLLVQKER 225

[Close]

BLAST of Heat shock protein 90 vs. Ensembl Nematostella
Match: EDO45344 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RT97])

HSP 1 Score: 360.533 bits (924), Expect = 2.157e-112
Identity = 202/414 (48.79%), Postives = 293/414 (70.77%), Query Frame = 3

Query:  852 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFEN-KKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNLKLGIHEDSVNRNKLADFLRYHSTSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTXX-XXXXXXXXXXXXXXXXXXXXXXXLCKVMK-DILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQAL---RDSSTMGYMAAKKHLEINPDHSVMKALKTRVDADKNDKSVKDLVMLLYETSLLSSGFALEDPQIHANRIHRMIKLGLG 2075
            LN  KPIWTR P ++  ++Y EFYKS T + ED LA  HF  EG++ FR++LF PK AP +LF +  KK + IKL+VRRVFI DN E+++P+YL+F++GVVDS+DLPLN+SRE LQQ+K+LKVI+K LV+K L++ ++I ++ D    F+++++ N+KLG+ ED  NR +LA  LR++S++S ++MTSL +Y+ RMKE Q  IY++ G ++  V  S FVE+L K G+EVLY+I+P+DEY +Q L E++GKK   V KE      + +++KKKFEE +  +EPL K +K D L  ++EK T+S RL  SPC +V S +GWS NMERIM++QA     D S   Y   KK LE+NP H ++K L  RV+ +K+D++ KDL  +L+ET+ L SG+ ++D    A RI RM++L +G
Sbjct:  353 LNTNKPIWTRKPKEIKDDEYNEFYKSFTKESEDPLAKIHFVAEGEVTFRSILFVPKAAPSNLFSDYGKKMDAIKLFVRRVFITDNFEEMMPKYLSFIRGVVDSDDLPLNVSREQLQQHKLLKVIKKKLVRKALDMIKKIPKE-DYMATFWKEYSTNIKLGVIEDHSNRTRLAKLLRFYSSNSEKDMTSLAEYIERMKEKQDVIYFMAGHNRKEVESSPFVEKLLKEGYEVLYLIEPVDEYCMQSLPEFEGKKFQNVAKEGLKIGEDSDKKKKKFEELEKTYEPLLKWLKEDALKDQIEKATISERLHDSPCALVASSYGWSGNMERIMRSQAYAKSSDPSNEYYATQKKTLEVNPRHPLVKQLLKRVEENKDDQTAKDLSRILFETATLRSGYLVKDSADFAGRIERMLRLSMG 765

HSP 2 Score: 217.238 bits (552), Expect = 7.355e-60
Identity = 124/225 (55.11%), Postives = 156/225 (69.33%), Query Frame = 3

Query:   21 FNINLMESMND-SETFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFMEALQAGAD----ISMIGQFGVGFYSSYLVADKVQVISKGNDDEQYLWESSAGGSFTIKPDTSEP-LGRGSKIILFMKEDQVEYLXXXXXXXXXXXHSQFIGYPIKLVLEK 677
             N+  M+ + D +E   FQAE+ +++ LIIN+ Y NKEIFLRELISNSSDALDKIR  SLTD +  D+  EL IKI  DK+   L + DTGIGMTK +LI NLGTIA+SGT  F + +Q  A       +IGQFGVGFYSS+LVAD+V V SK NDD+QY+WES A  SF+I  D   P L RG+ I L +KE+  +YLE   IK+++KK+SQFI +PI L   K
Sbjct:   64 LNVAQMKELRDKAEKHEFQAEVNRMMKLIINSLYRNKEIFLRELISNSSDALDKIRLMSLTDKTAFDSGDELSIKIKADKENNILHVTDTGIGMTKEELIKNLGTIAKSGTSEFFQKIQEAASSDSASDLIGQFGVGFYSSFLVADRVIVTSKNNDDKQYIWESDA-SSFSISEDPRGPTLKRGTTISLHLKEEARDYLEPETIKDLVKKYSQFINFPIFLWTSK 287

[Close]

BLAST of Heat shock protein 90 vs. Ensembl Nematostella
Match: EDO45666 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RS03])

HSP 1 Score: 170.629 bits (431), Expect = 8.310e-45
Identity = 91/204 (44.61%), Postives = 138/204 (67.65%), Query Frame = 3

Query:   69 FQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFMEALQAGADIS---MIGQFGVGFYSSYLVADKVQVISKG--NDDEQYLWESSAGGSFTIKPDTSEPLGRGSKIILFMKEDQVEYLXXXXXXXXXXXHSQFIGYPIKL 665
            FQAE  QLL ++  + YS KE+F+RE+ISN+SDAL+K+R+  LT   V +T   L I I  D++AGT TI D G+GMT+ +L+++LG IA+SG+K FME L+  A  S   +IGQFGVGFYS+++VADKV V +K    + + Y W S   GS+      +  + RG+K++L +KED   +  +  +++I++++S F+G+PI L
Sbjct:   15 FQAETKQLLDIVAKSLYSEKEVFIREVISNASDALEKVRHFFLTGKDVSETETSLEIMIETDQEAGTFTIQDNGVGMTEEELMDHLGVIAKSGSKVFMEKLKNEARSSHENIIGQFGVGFYSTFMVADKVDVYTKSYQPNSQGYFWTSDGSGSYEYA--EANGVARGTKLVLHLKEDCKRFAMKTAVEDIVQRYSNFVGFPIYL 216

HSP 2 Score: 164.851 bits (416), Expect = 6.403e-43
Identity = 105/367 (28.61%), Postives = 192/367 (52.32%), Query Frame = 3

Query:  852 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELF-EEIMEDKDNYKKFYEQFAKNLKLGI--HEDSVNRNKLADFLRYHSTSSGE-EMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTX--XXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDK-KVEKVTVSNRLVSS--PCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSVMKALK 1925
            +N  +P+WT  P D+S+E + EFY+ L+  ++      H+  +  L  R++ + P+  P  +F  ++  + I LY RRV I    E ++P +L F++GVVDSED+PLN+SRE+LQ + ++K +   L  + ++   E+  +D+  Y+KF++     ++ G+   ED   + ++A  L + S++     +T+L  Y+SRMK  QK +YY+   S+D    S + E L +   EVL+  +  D+  +  L++Y+ K ++         E  + + E +  +      + L   M  IL   +V  V VS RL ++  P  I       + +  +++K +  ++   M Y   +  LEINP H ++K L+
Sbjct:  221 INTIQPLWTLEPRDISKEQHDEFYQFLSKGYDKPRYYLHYKTDAPLNIRSIFYFPETLP-QMFNMQQMESGISLYSRRVLIQAKAEKVLPRWLRFIRGVVDSEDIPLNLSRELLQDSALIKKLSNVLSARLVKFLQEQARKDRVKYEKFFKDCGIFIREGVVTTEDEEQKEEIAKLLLFESSNEKPGTLTNLPAYVSRMKPTQKKVYYLCAPSRDLAETSPYYETLKQNDVEVLFSYNEQDDVVLHYLRKYENKAVISAENFLSEAEDTKPKNEPEVEDVTPEEGKDLAGWMSSILGPTRVVGVKVSKRLANTNHPAMITVPDMVAAKHWLKLIKTEHNKEVENMKYQIIQPTLEINPKHDLIKRLE 586

[Close]

BLAST of Heat shock protein 90 vs. Ensembl Medaka
Match: hsp90ab1 (heat shock protein 90 alpha family class B member 1 [Source:NCBI gene;Acc:100125466])

HSP 1 Score: 952.97 bits (2462), Expect = 0.000e+0
Identity = 533/712 (74.86%), Postives = 619/712 (86.94%), Query Frame = 3

Query:   60 TFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKGNDDEQYLWESSAGGSFTIKPDTSEPLGRGSKIILFMKEDQVEYLXXXXXXXXXXXHSQFIGYPIKLVL--EKERDKEVSDDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNLKLGIHEDSVNRNKLADFLRYHSTSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSVMKALKTRVDADKNDKSVKDLVMLLYETSLLSSGFALEDPQIHANRIHRMIKLGLGX----XXXXXXXXXXXVGDVPVGPSATEDEAGKMEEVD 2177
            TFAFQAEIAQL+SLIINTFYSNKEIFLRELISN+SDALDKIRY+SLTDPS LD+ K+L I IIP+K   TLTI+DTGIGMTK+DLINNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVA++V VI+K NDDEQY WESSAGGSFT+K D+ EP+GRG+KIIL +KEDQ EY+EE+++KEI+KKHSQFIGYPI L +  E++++    + E E E K+ + E  +     +   D+E+D K   KKKKKIKEKYID+EELNKTKPIWTRNPDD++ E+Y EFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF P+RAPFDLFENKKK+NNIKLYVRRVFIMDNCE+LIPEYLNF++GVVDSEDLPLNISREMLQQ+KILKVIRKN+VKKCLELF E+ EDK+NYKKFYE F+KN+KLGIHEDS NR KL++ LRYHS+ SG+EMTSL +YLSRMKENQK IYYITGESKD VA+SAFVER+ KRGFEVLYM +PIDEY VQQLKE+DGK LV VTKEGLELPEDEEEKKK E+ KA FE LCK+MK+ILDKKVEKVTVSNRLVSSPCCIVTS +GW+ANMERIMKAQALRD+STMGYM AKKHLEINPDH +M+ L+ + + DKNDK+VKDLV+LL+ET+LLSSGF+L+DPQ H+NRI+RMIKLGLGI       +    T+   ++P      +D++ +MEEVD
Sbjct:   13 TFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKDLKIDIIPNKADRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAERVVVITKHNDDEQYAWESSAGGSFTVKVDSGEPIGRGTKIILHLKEDQTEYIEEKRVKEIVKKHSQFIGYPITLFVEKERDKEISDDEAEEEKEEKETKEEGEDKPKIEDVGSDDEEDAKDKGKKKKKIKEKYIDQEELNKTKPIWTRNPDDITSEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENKKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFGELAEDKENYKKFYEGFSKNIKLGIHEDSQNRKKLSELLRYHSSQSGDEMTSLTEYLSRMKENQKSIYYITGESKDQVANSAFVERVRKRGFEVLYMTEPIDEYCVQQLKEFDGKNLVSVTKEGLELPEDEEEKKKMEDDKAKFENLCKLMKEILDKKVEKVTVSNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIMETLRQKAETDKNDKAVKDLVILLFETALLSSGFSLDDPQTHSNRIYRMIKLGLGIDDDDIPTEEPASTSAPEEMPPLEGDADDDSSRMEEVD 724

[Close]

BLAST of Heat shock protein 90 vs. Ensembl Medaka
Match: hsp90ab1 (heat shock protein 90 alpha family class B member 1 [Source:NCBI gene;Acc:100125466])

HSP 1 Score: 922.924 bits (2384), Expect = 0.000e+0
Identity = 521/712 (73.17%), Postives = 605/712 (84.97%), Query Frame = 3

Query:   60 TFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKGNDDEQYLWESSAGGSFTIKPDTSEPLGRGSKIILFMKEDQVEYLXXXXXXXXXXXHSQFIGYPIKLVL--EKERDKEVSDDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNLKLGIHEDSVNRNKLADFLRYHSTSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSVMKALKTRVDADKNDKSVKDLVMLLYETSLLSSGFALEDPQIHANRIHRMIKLGLGX----XXXXXXXXXXXVGDVPVGPSATEDEAGKMEEVD 2177
            TFAFQAEIAQL+SLIINTFYSNKEIFLRELISN+SDALDKIRY+SLTDPS LD+ K+L I IIP+K   TLTI+DTGIGMTK+DLINNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVA++V VI+K NDDEQY WESSAGGSFT+K D+ EP+GRG+KIIL +KEDQ EY+EE+++KEI+KKHSQFIGYPI L +  E++++    + E E E K+ + E  +     +   D+E+D K   KKKKKIKEKYID+EELNKTKPIWTRNPDD++ E+Y EFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF P+RAPFDLFENKKK+NNIKLYVRRVFIMDNCE+LIPEYLNF++GVVDSEDLPLNISREMLQQ+KILKVIRKN+VKKCLELF E+ EDK+NYKKFYE F+KN+KLGIHEDS NR KL++ LRYHS+ SG+EMTSL +YLSRMKENQK IYYITGESKD VA+SAFVER+ KRGFEVLYM +PIDEY VQQLKE+DGK LV VTKEGLELPEDEEEKKK E+                 KKVEKVTVSNRLVSSPCCIVTS +GW+ANMERIMKAQALRD+STMGYM AKKHLEINPDH +M+ L+ + + DKNDK+VKDLV+LL+ET+LLSSGF+L+DPQ H+NRI+RMIKLGLGI       +    T+   ++P      +D++ +MEEVD
Sbjct:   13 TFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKDLKIDIIPNKADRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAERVVVITKHNDDEQYAWESSAGGSFTVKVDSGEPIGRGTKIILHLKEDQTEYIEEKRVKEIVKKHSQFIGYPITLFVEKERDKEISDDEAEEEKEEKETKEEGEDKPKIEDVGSDDEEDAKDKGKKKKKIKEKYIDQEELNKTKPIWTRNPDDITSEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENKKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFGELAEDKENYKKFYEGFSKNIKLGIHEDSQNRKKLSELLRYHSSQSGDEMTSLTEYLSRMKENQKSIYYITGESKDQVANSAFVERVRKRGFEVLYMTEPIDEYCVQQLKEFDGKNLVSVTKEGLELPEDEEEKKKMEDD----------------KKVEKVTVSNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIMETLRQKAETDKNDKAVKDLVILLFETALLSSGFSLDDPQTHSNRIYRMIKLGLGIDDDDIPTEEPASTSAPEEMPPLEGDADDDSSRMEEVD 708

[Close]

BLAST of Heat shock protein 90 vs. Ensembl Medaka
Match: hsp90aa1.2 (heat shock protein HSP 90-alpha [Source:NCBI gene;Acc:101169506])

HSP 1 Score: 680.248 bits (1754), Expect = 0.000e+0
Identity = 351/445 (78.88%), Postives = 397/445 (89.21%), Query Frame = 3

Query:  852 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNLKLGIHEDSVNRNKLADFLRYHSTSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSVMKALKTRVDADKNDKSVKDLVMLLYETSLLSSGFALEDPQIHANRIHRMIKLGLGX---XXXXXXXXXXXVGDVPVGPSATEDEAGKMEEVD 2177
            LNKTKPIWTRNPDD++ E+Y EFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF P+RA FDLFENKKKRNNIKLYVRRVFIMDNC++LIPEYLNF+KGVVDSEDLPLNISREMLQQ+KILKVIRKNLVKKCLELF E+ EDKDNYKK YEQF+KN+KLGIHEDS NR KL++ LRY++++SG+EM SLKDY+SRMK+NQK IYYITGE+KD VA+SAFVERL K G EV+YMI+PIDEY VQQLK++DGK LV VTKEGLELPEDEEEKKK EE+KA FE LCK+MKDIL+KKVEKVTVSNRLVSSPCCIVTS +GW+ANMERIMKAQALRD+STMGYMAAKKHLEINPDH +M+ L+ + +ADKNDKSVKDLV+LL+ET+LLSSGF LEDPQ HANRI+RMIKLGLGI   D    E  +    D+P  P   +D+A +MEEVD
Sbjct:  282 LNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAAFDLFENKKKRNNIKLYVRRVFIMDNCDELIPEYLNFIKGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELSEDKDNYKKLYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYVSRMKDNQKHIYYITGETKDQVANSAFVERLRKAGLEVIYMIEPIDEYCVQQLKDFDGKNLVSVTKEGLELPEDEEEKKKQEEKKAQFENLCKIMKDILEKKVEKVTVSNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHPIMETLRQKAEADKNDKSVKDLVILLFETALLSSGFTLEDPQTHANRIYRMIKLGLGIDEDDTPVEETTSAPTEDMP--PLEGDDDASRMEEVD 724

HSP 2 Score: 340.887 bits (873), Expect = 9.211e-106
Identity = 173/213 (81.22%), Postives = 195/213 (91.55%), Query Frame = 3

Query:   57 ETFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKGNDDEQYLWESSAGGSFTIKPDTSEPLGRGSKIILFMKEDQVEYLXXXXXXXXXXXHSQFIGYPIKLVLEKERDKEV 695
            ETFAFQAEIAQL+SLIINTFYSNKEIFLRELISNSSDALDKIRY+SLTDPS LD+ KEL I++ PD  A TLTI DTGIGMTK+DLINNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVA+KV VI+K NDDEQY+WES+AGGSFT+KPD  EP+GRG+K+IL +KEDQ EY EE++IKE+IKKHSQFIGYPI L +EK R+KEV
Sbjct:   14 ETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSCKELKIEVRPDLHARTLTINDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYIWESAAGGSFTVKPDNGEPIGRGTKVILHLKEDQTEYCEEKRIKEVIKKHSQFIGYPITLYVEKTREKEV 226

[Close]

BLAST of Heat shock protein 90 vs. Ensembl Medaka
Match: hsp90aa1.2 (heat shock protein HSP 90-alpha [Source:NCBI gene;Acc:101169506])

HSP 1 Score: 679.478 bits (1752), Expect = 0.000e+0
Identity = 350/445 (78.65%), Postives = 397/445 (89.21%), Query Frame = 3

Query:  852 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNLKLGIHEDSVNRNKLADFLRYHSTSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSVMKALKTRVDADKNDKSVKDLVMLLYETSLLSSGFALEDPQIHANRIHRMIKLGLGX---XXXXXXXXXXXVGDVPVGPSATEDEAGKMEEVD 2177
            LNKTKPIWTRNPDD++ E+Y EFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF P+RA FDLFENKKKRNNIKLYVRRVFIMDNC++LIPEYLNF+KGVVDSEDLPLNISREMLQQ+KILKVIRKNLVKKCLELF E+ EDKDNYKK YEQF+KN+KLGIHEDS NR KL++ LRY++++SG+EM SLKDY++RMK+NQK IYYITGE+KD VA+SAFVERL K G EV+YMI+PIDEY VQQLK++DGK LV VTKEGLELPEDEEEKKK EE+KA FE LCK+MKDIL+KKVEKVTVSNRLVSSPCCIVTS +GW+ANMERIMKAQALRD+STMGYMAAKKHLEINPDH +M+ L+ + +ADKNDKSVKDLV+LL+ET+LLSSGF LEDPQ HANRI+RMIKLGLGI   D    E  +    D+P  P   +D+A +MEEVD
Sbjct:  282 LNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAAFDLFENKKKRNNIKLYVRRVFIMDNCDELIPEYLNFIKGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELSEDKDNYKKLYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYVTRMKDNQKHIYYITGETKDQVANSAFVERLRKAGLEVIYMIEPIDEYCVQQLKDFDGKNLVSVTKEGLELPEDEEEKKKQEEKKAQFENLCKIMKDILEKKVEKVTVSNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHPIMETLRQKAEADKNDKSVKDLVILLFETALLSSGFTLEDPQTHANRIYRMIKLGLGIDEDDTPVEETTSAPTEDMP--PLEGDDDASRMEEVD 724

HSP 2 Score: 340.887 bits (873), Expect = 8.293e-106
Identity = 173/213 (81.22%), Postives = 195/213 (91.55%), Query Frame = 3

Query:   57 ETFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKGNDDEQYLWESSAGGSFTIKPDTSEPLGRGSKIILFMKEDQVEYLXXXXXXXXXXXHSQFIGYPIKLVLEKERDKEV 695
            ETFAFQAEIAQL+SLIINTFYSNKEIFLRELISNSSDALDKIRY+SLTDPS LD+ KEL I++ PD  A TLTI DTGIGMTK+DLINNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVA+KV VI+K NDDEQY+WES+AGGSFT+KPD  EP+GRG+K+IL +KEDQ EY EE++IKE+IKKHSQFIGYPI L +EK R+KEV
Sbjct:   14 ETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSCKELKIEVRPDLHARTLTINDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYIWESAAGGSFTVKPDNGEPIGRGTKVILHLKEDQTEYCEEKRIKEVIKKHSQFIGYPITLYVEKTREKEV 226

[Close]

BLAST of Heat shock protein 90 vs. Ensembl Medaka
Match: hsp90aa1.2 (heat shock protein HSP 90-alpha [Source:NCBI gene;Acc:101169506])

HSP 1 Score: 678.707 bits (1750), Expect = 0.000e+0
Identity = 349/445 (78.43%), Postives = 397/445 (89.21%), Query Frame = 3

Query:  852 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNLKLGIHEDSVNRNKLADFLRYHSTSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSVMKALKTRVDADKNDKSVKDLVMLLYETSLLSSGFALEDPQIHANRIHRMIKLGLGX---XXXXXXXXXXXVGDVPVGPSATEDEAGKMEEVD 2177
            LNKTKPIWTRNPDD++ E+Y EFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF P+RA FDLFENKKKRNNIKLYVRRVFIMDNC++LIPEYLNF++GVVDSEDLPLNISREMLQQ+KILKVIRKNLVKKCLELF E+ EDKDNYKK YEQF+KN+KLGIHEDS NR KL++ LRY++++SG+EM SLKDY++RMK+NQK IYYITGE+KD VA+SAFVERL K G EV+YMI+PIDEY VQQLK++DGK LV VTKEGLELPEDEEEKKK EE+KA FE LCK+MKDIL+KKVEKVTVSNRLVSSPCCIVTS +GW+ANMERIMKAQALRD+STMGYMAAKKHLEINPDH +M+ L+ + +ADKNDKSVKDLV+LL+ET+LLSSGF LEDPQ HANRI+RMIKLGLGI   D    E  +    D+P  P   +D+A +MEEVD
Sbjct:  282 LNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAAFDLFENKKKRNNIKLYVRRVFIMDNCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELSEDKDNYKKLYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYVTRMKDNQKHIYYITGETKDQVANSAFVERLRKAGLEVIYMIEPIDEYCVQQLKDFDGKNLVSVTKEGLELPEDEEEKKKQEEKKAQFENLCKIMKDILEKKVEKVTVSNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHPIMETLRQKAEADKNDKSVKDLVILLFETALLSSGFTLEDPQTHANRIYRMIKLGLGIDEDDTPVEETTSAPTEDMP--PLEGDDDASRMEEVD 724

HSP 2 Score: 340.887 bits (873), Expect = 8.120e-106
Identity = 173/213 (81.22%), Postives = 195/213 (91.55%), Query Frame = 3

Query:   57 ETFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKGNDDEQYLWESSAGGSFTIKPDTSEPLGRGSKIILFMKEDQVEYLXXXXXXXXXXXHSQFIGYPIKLVLEKERDKEV 695
            ETFAFQAEIAQL+SLIINTFYSNKEIFLRELISNSSDALDKIRY+SLTDPS LD+ KEL I++ PD  A TLTI DTGIGMTK+DLINNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVA+KV VI+K NDDEQY+WES+AGGSFT+KPD  EP+GRG+K+IL +KEDQ EY EE++IKE+IKKHSQFIGYPI L +EK R+KEV
Sbjct:   14 ETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSCKELKIEVRPDLHARTLTINDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYIWESAAGGSFTVKPDNGEPIGRGTKVILHLKEDQTEYCEEKRIKEVIKKHSQFIGYPITLYVEKTREKEV 226

[Close]

BLAST of Heat shock protein 90 vs. Planmine SMEST
Match: SMESG000024822.1 (SMESG000024822.1)

HSP 1 Score: 1231.47 bits (3185), Expect = 0.000e+0
Identity = 714/714 (100.00%), Postives = 714/714 (100.00%), Query Frame = 3

Query:   36 MESMNDSETFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKGNDDEQYLWESSAGGSFTIKPDTSEPLGRGSKIILFMKEDQVEYLXXXXXXXXXXXHSQFIGYPIKLVLEKERDKEVSDDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNLKLGIHEDSVNRNKLADFLRYHSTSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSVMKALKTRVDADKNDKSVKDLVMLLYETSLLSSGFALEDPQIHANRIHRMIKLGLGXXXXXXXXXXXXVGDVPVGPSATEDEAGKMEEVD 2177
            MESMNDSETFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKGNDDEQYLWESSAGGSFTIKPDTSEPLGRGSKIILFMKEDQVEYLEERKIKEIIKKHSQFIGYPIKLVLEKERDKEVSDDEAETETKKEESEEGEDKPKIEDLDDEEDDDKKDKKKKKKIKEKYIDEEELNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNLKLGIHEDSVNRNKLADFLRYHSTSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTKEGLELPEDEEEKKKFEEQKAAFEPLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSVMKALKTRVDADKNDKSVKDLVMLLYETSLLSSGFALEDPQIHANRIHRMIKLGLGIDEDDMEIDTTEVGDVPVGPSATEDEAGKMEEVD
Sbjct:    1 MESMNDSETFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKGNDDEQYLWESSAGGSFTIKPDTSEPLGRGSKIILFMKEDQVEYLEERKIKEIIKKHSQFIGYPIKLVLEKERDKEVSDDEAETETKKEESEEGEDKPKIEDLDDEEDDDKKDKKKKKKIKEKYIDEEELNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNLKLGIHEDSVNRNKLADFLRYHSTSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTKEGLELPEDEEEKKKFEEQKAAFEPLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSVMKALKTRVDADKNDKSVKDLVMLLYETSLLSSGFALEDPQIHANRIHRMIKLGLGIDEDDMEIDTTEVGDVPVGPSATEDEAGKMEEVD 714

[Close]

BLAST of Heat shock protein 90 vs. Planmine SMEST
Match: SMESG000071533.1 (SMESG000071533.1)

HSP 1 Score: 1169.84 bits (3025), Expect = 0.000e+0
Identity = 645/714 (90.34%), Postives = 684/714 (95.80%), Query Frame = 3

Query:   42 SMNDSETFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKGNDDEQYLWESSAGGSFTIKPDTSEPLGRGSKIILFMKEDQVEYLXXXXXXXXXXXHSQFIGYPIKLVLEKERDKEVSDDXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNLKLGIHEDSVNRNKLADFLRYHSTSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSVMKALKTRVDADKNDKSVKDLVMLLYETSLLSSGFALEDPQIHANRIHRMIKLGLGXXXXXXXXXXXXVGDVPVGPSATEDEAGKMEEVD 2177
            S  D+ETFAFQAEIAQL+SLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLD+AK+L+IKIIPDKDAGTLTIIDTGIGMTK+DLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISK NDDEQYLWESSAGGSFTIK D SEP+GRGSK+IL+MKEDQ+EYL+E+KIKEIIKKHSQFIGYPIKLVLEKERDKE+SDDEAE   + +KE  +  +     +  D+E+DD K   KKKKKIKEKYIDEEELNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKN+KLGIHEDSVNRNK+A+FLR++STSSGEEMTSLKDY+SRMKENQKDIYYITGESKDNV HSAFVERLTKRGFEVL M+DPIDEYSVQQLKEYDGKKLVCVTKEGLELPEDE+EKKKFEEQKAAFEPLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHS+MK+LK RVDADKNDKSVKDLVMLL+ETSLLSSGF+LEDPQ+H NRIHRMIKLGLGI++DD+EID TE GD+PVGP++TEDEAGKMEEVD
Sbjct:    2 SETDAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIIDTGIGMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDNSEPIGRGSKVILYMKEDQIEYLDEKKIKEIIKKHSQFIGYPIKLVLEKERDKEISDDEAEVDDKKEKESEDTEDKPKIEDLDDEEDDDKKDKDKKKKKIKEKYIDEEELNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTKEGLELPEDEDEKKKFEEQKAAFEPLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKSLKLRVDADKNDKSVKDLVMLLFETSLLSSGFSLEDPQVHGNRIHRMIKLGLGIEDDDVEIDATEAGDIPVGPTSTEDEAGKMEEVD 715

[Close]

BLAST of Heat shock protein 90 vs. Planmine SMEST
Match: SMESG000071531.1 (SMESG000071531.1)

HSP 1 Score: 771.541 bits (1991), Expect = 0.000e+0
Identity = 403/430 (93.72%), Postives = 424/430 (98.60%), Query Frame = 3

Query:  888 DDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNLKLGIHEDSVNRNKLADFLRYHSTSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSVMKALKTRVDADKNDKSVKDLVMLLYETSLLSSGFALEDPQIHANRIHRMIKLGLGXXXXXXXXXXXXVGDVPVGPSATEDEAGKMEEVD 2177
            +DVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKN+KLGIHEDSVNRNK+A+FLR++STSSGEEMTSLKDY++RMKENQKDIYYITGESKDNV HSAFVERLTKRGFEVL M+DPIDEYSVQQLKEYDGKKLVCVTKEGLELPEDE+EKKKFEEQKAAFEPLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHS+MK+LK RVDADKNDKSVKDLVMLL+ETSLLSSGF+LEDPQ+H NRIHRMIKLGLGI++DD+EID TE GD+PVGP++TEDEAGKMEEVD
Sbjct:  267 NDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYITRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTKEGLELPEDEDEKKKFEEQKAAFEPLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKSLKLRVDADKNDKSVKDLVMLLFETSLLSSGFSLEDPQVHGNRIHRMIKLGLGIEDDDVEIDATEAGDIPVGPTSTEDEAGKMEEVD 696

HSP 2 Score: 395.201 bits (1014), Expect = 6.376e-127
Identity = 203/221 (91.86%), Postives = 216/221 (97.74%), Query Frame = 3

Query:   42 SMNDSETFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKGNDDEQYLWESSAGGSFTIKPDTSEPLGRGSKIILFMKEDQVEYLXXXXXXXXXXXHSQFIGYPIKLVLEKERDKEVSDD 704
            S  D+ETFAFQAEIAQL+SLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLD+AK+L+IKIIPDKDAGTLTIIDTGIGMTK+DLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISK NDDEQYLWESSAGGSFTIK D SEP+GRGSK+IL+MKEDQ+EYL+E+KIKEIIKKHSQFIGYPIKLVLEKERDKE+SDD
Sbjct:    2 SETDAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIIDTGIGMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDNSEPIGRGSKVILYMKEDQIEYLDEKKIKEIIKKHSQFIGYPIKLVLEKERDKEISDD 222

[Close]

BLAST of Heat shock protein 90 vs. Planmine SMEST
Match: SMESG000025598.1 (SMESG000025598.1)

HSP 1 Score: 738.413 bits (1905), Expect = 0.000e+0
Identity = 381/443 (86.00%), Postives = 419/443 (94.58%), Query Frame = 3

Query:  852 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNLKLGIHEDSVNRNKLADFLRYHSTSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSVMKALKTRVDADKNDKSVKDLVMLLYETSLLSSGFALEDPQIHANRIHRMIKLGLGX-XXXXXXXXXXXVGDVPVGPSATEDEAGKMEEVD 2177
            LNKTKPIWTRNPDD+SQEDY+EFYKSL+NDWEDHLAVKHF+VEGQLEF+A+LFCPKRA FD+FENKKKRNNIKLYVRRVFIMDNCEDLIPEYL+F+KGVVDSEDLPLNISREMLQQNKILKV+RKN+VKKC+ELF+EIMEDKDNYKKFYEQFAKN+KLGIHEDSVNRNKLA+FLRY+STSSGEEM SLKDY+SRMKENQKDIYYITGE+K+ VA SAFVERL+KRGFEVL+M+DPIDEYSVQQLKE+DGKKLVCVTKEGLELPEDEEEKKKFEEQKA FE LCKVMKD+LDKKVEKVTVSNRLV SPCC+VTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHS+MK+LK RVD DKNDK+VKDL+ LL+ETSLL+SGF+LE+PQ+H NRIHRMIKLGLGI +E+ +E  T  V D  + PSA EDE  KMEEVD
Sbjct:  268 LNKTKPIWTRNPDDISQEDYSEFYKSLSNDWEDHLAVKHFAVEGQLEFKAILFCPKRASFDMFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLSFIKGVVDSEDLPLNISREMLQQNKILKVVRKNIVKKCIELFDEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKLAEFLRYNSTSSGEEMISLKDYVSRMKENQKDIYYITGENKETVAKSAFVERLSKRGFEVLFMVDPIDEYSVQQLKEFDGKKLVCVTKEGLELPEDEEEKKKFEEQKAEFESLCKVMKDVLDKKVEKVTVSNRLVDSPCCVVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKSLKKRVDTDKNDKAVKDLINLLFETSLLTSGFSLEEPQVHGNRIHRMIKLGLGIDEEESVEEITEAVAD--LAPSAVEDEE-KMEEVD 707

HSP 2 Score: 362.073 bits (928), Expect = 3.352e-114
Identity = 182/217 (83.87%), Postives = 207/217 (95.39%), Query Frame = 3

Query:   36 MESMNDSETFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKGNDDEQYLWESSAGGSFTIKPDTSEPLGRGSKIILFMKEDQVEYLXXXXXXXXXXXHSQFIGYPIKLVLEKERD 686
            M ++ ++ETFAFQAEI+QL+SLIINTFYSNKEIFLRELISN+SDALDK+RYKSLTDPSVLD+ KEL+IK+IPDKD+ TLT+ DTG+GMTK++LINNLGTIARSGTKAFMEAL AGADISMIGQFGVGFYS+YLVAD+VQVI+K N+DEQY+WESSAGGSFTIK D SEP+GRG+KIIL MKEDQVEYL+E+KIKEIIKKHSQFIGYPIKLVLEKERD
Sbjct:    1 MSNIPEAETFAFQAEISQLMSLIINTFYSNKEIFLRELISNASDALDKVRYKSLTDPSVLDSQKELMIKVIPDKDSNTLTLYDTGVGMTKAELINNLGTIARSGTKAFMEALTAGADISMIGQFGVGFYSAYLVADRVQVITKSNEDEQYMWESSAGGSFTIKHDDSEPIGRGTKIILHMKEDQVEYLDEKKIKEIIKKHSQFIGYPIKLVLEKERD 217

[Close]

BLAST of Heat shock protein 90 vs. Planmine SMEST
Match: SMESG000054819.1 (SMESG000054819.1)

HSP 1 Score: 501.516 bits (1290), Expect = 9.843e-167
Identity = 302/681 (44.35%), Postives = 446/681 (65.49%), Query Frame = 3

Query:   54 SETFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFM----EALQAGADISMIGQFGVGFYSSYLVADKVQVISKGNDDEQYLWESSAGGSFTIKPDTSEPLGRGSKIILFMKEDQVEYLXXXXXXXXXXXHSQFIGYPIKLVLEKERDKEVSDDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNLKLGIHEDSVNRNKLADFLRYHSTSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDI-LDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMG---YMAAKKHLEINPDHSVMKALKTRVDADKNDKSVKDLVMLLYETSLLSSGFALEDPQIHANRIHRMIKLGL 2072
            +E + FQAE+ +++ LIIN+ Y NKEIFLRELISN+SDALDKIR+ SLT+       ++L IKI  DK A T+ I+DTG+GMTK++LI NLGTIA+SGT  F+    EA   G    +IGQFGVGFYSS+LVADKV VISK + D QY+WES A     ++      L RG+++IL +K++ +E+LE   ++ +I K+SQFI +PI   L K   K V +D     +K++E    E++ + +  +    D +                  +NK KPIWTR   +   E+Y EFYKS + D E+ LA  HF+ EG+++F+A+L+ PK++  +     KK +NIKLYV+RVFI D+ +D++P+YL+F+KG++DS+DLPLN+SRE LQQ+K+LKVI+K LV+K L++F+++ ED   +K+F++++A N+KLG+ ED  NRN+LA  +R+ S+ S E  TSL DY+SRMK  Q  I++I G S  +V  S  VE L K+ +EVLY+I+PIDEY+ Q L E++GKK   V KEG +L + +++ +  E+ +  +EPL   +K   L   +EKV +S RL +SPC ++ S +GWS NMERIMKAQA + S  +     +  KK LEIN  HS+++ LK      ++    + L   LY+T+LL SG+ +++    + ++H +IK  +
Sbjct:   93 AEKYTFQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNEDLYIKIKADKAAKTIHILDTGVGMTKTELIKNLGTIAKSGTSDFIQKLSEAKNTGELNELIGQFGVGFYSSFLVADKVTVISKSDADYQYIWESDASTFSIVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPI--YLWKSSVKNVDEDHESAVSKRDEDANVENENERKSTERTVWDWEL-----------------VNKNKPIWTRKSGETPDEEYNEFYKSFSKDSENPLAKTHFTAEGEVQFKAILYIPKKSNVEFNSVDKKNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQQHKLLKVIKKKLVRKTLDMFKKLPEDI--FKEFWKEYATNIKLGVIEDVSNRNRLAKLIRFWSSHSQESQTSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILLKKQYEVLYLIEPIDEYTFQSLPEFEGKKFQNVAKEGFKLDDSDKKIEIKEKLEKEYEPLINWLKSTELKDYIEKVEISERLTTSPCVLIASTYGWSGNMERIMKAQAYQKSEEVMQTYQVNQKKILEINTQHSLIRHLKYSFSNGQDMNETRKLAKFLYDTALLRSGYIMDNVASFSKQVHEIIKTSM 752

The following BLAST results are available for this feature:

BLAST of Heat shock protein 90 vs. Ensembl Human
BLAST of Heat shock protein 90 vs. Ensembl Celegans
BLAST of Heat shock protein 90 vs. Ensembl Fly
BLAST of Heat shock protein 90 vs. Ensembl Zebrafish
BLAST of Heat shock protein 90 vs. Ensembl Xenopus
BLAST of Heat shock protein 90 vs. Ensembl Mouse
BLAST of Heat shock protein 90 vs. UniProt/SwissProt
BLAST of Heat shock protein 90 vs. TrEMBL
BLAST of Heat shock protein 90 vs. Ensembl Cavefish
BLAST of Heat shock protein 90 vs. Ensembl Sea Lamprey
BLAST of Heat shock protein 90 vs. Ensembl Yeast
BLAST of Heat shock protein 90 vs. Ensembl Nematostella
BLAST of Heat shock protein 90 vs. Ensembl Medaka
BLAST of Heat shock protein 90 vs. Planmine SMEST

BLAST of Heat shock protein 90 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
HSP90AA1	1.092e-108	78.65	heat shock protein 90 alpha family class A member ...	[more]
HSP90AA1	6.926e-107	78.65	heat shock protein 90 alpha family class A member ...	[more]
HSP90AB1	4.198e-105	77.48	heat shock protein 90 alpha family class B member ...	[more]
HSP90AB1	4.198e-105	77.48	heat shock protein 90 alpha family class B member ...	[more]
HSP90AB1	4.198e-105	77.48	heat shock protein 90 alpha family class B member ...	[more]

BLAST of Heat shock protein 90 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
hsp-90	1.483e-95	77.36	Heat shock protein 90 [Source:UniProtKB/Swiss-Pro...	[more]
hsp-90	1.483e-95	77.36	Heat shock protein 90 [Source:UniProtKB/Swiss-Pro...	[more]
hsp-90	1.483e-95	77.36	Heat shock protein 90 [Source:UniProtKB/Swiss-Pro...	[more]
hsp-90	1.483e-95	77.36	Heat shock protein 90 [Source:UniProtKB/Swiss-Pro...	[more]
enpl-1	1.729e-104	45.15	Endoplasmin homolog [Source:UniProtKB/Swiss-Prot;...	[more]

BLAST of Heat shock protein 90 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Hsp83	0.000e+0	75.80	gene:FBgn0001233 transcript:FBtr0332873	[more]
Hsp83	0.000e+0	75.80	gene:FBgn0001233 transcript:FBtr0073040	[more]
Gp93	3.999e-105	46.73	gene:FBgn0039562 transcript:FBtr0085254	[more]
Trap1	3.575e-46	29.22	gene:FBgn0026761 transcript:FBtr0086149	[more]
Trap1	3.575e-46	29.22	gene:FBgn0026761 transcript:FBtr0336666	[more]

BLAST of Heat shock protein 90 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
hsp90aa1.1	8.804e-106	77.30	heat shock protein 90, alpha (cytosolic), class A ...	[more]
hsp90aa1.1	8.804e-106	77.30	heat shock protein 90, alpha (cytosolic), class A ...	[more]
hsp90ab1	3.621e-104	78.30	heat shock protein 90, alpha (cytosolic), class A ...	[more]
hsp90ab1	3.621e-104	78.30	heat shock protein 90, alpha (cytosolic), class A ...	[more]
hsp90aa1.2	2.868e-107	77.43	heat shock protein 90, alpha (cytosolic), class A ...	[more]

BLAST of Heat shock protein 90 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ccdc173	0.000e+0	73.68	coiled-coil domain containing 173 [Source:Xenbase;...	[more]
ccdc173	0.000e+0	74.02	coiled-coil domain containing 173 [Source:Xenbase;...	[more]
uck1	0.000e+0	72.78	uridine-cytidine kinase 1 [Source:Xenbase;Acc:XB-G...	[more]
ccdc173	0.000e+0	72.95	coiled-coil domain containing 173 [Source:Xenbase;...	[more]
ccdc173	0.000e+0	71.51	coiled-coil domain containing 173 [Source:Xenbase;...	[more]

BLAST of Heat shock protein 90 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Hsp90aa1	3.480e-110	78.20	heat shock protein 90, alpha (cytosolic), class A ...	[more]
Hsp90aa1	3.480e-110	78.20	heat shock protein 90, alpha (cytosolic), class A ...	[more]
Hsp90ab1	2.622e-105	77.48	heat shock protein 90 alpha (cytosolic), class B m...	[more]
Hsp90b1	1.099e-119	48.43	heat shock protein 90, beta (Grp94), member 1 [Sou...	[more]
Hsp90aa1	2.059e-101	82.87	heat shock protein 90, alpha (cytosolic), class A ...	[more]

BLAST of Heat shock protein 90 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|P30946\|HS90A_RABIT	0.000e+0	72.96	Heat shock protein HSP 90-alpha OS=Oryctolagus cun...	[more]
sp\|P02828\|HSP83_DROME	0.000e+0	75.80	Heat shock protein 83 OS=Drosophila melanogaster O...	[more]
sp\|P04809\|HSP83_DROPS	0.000e+0	75.52	Heat shock protein 83 OS=Drosophila pseudoobscura ...	[more]
sp\|P06660\|HSP85_TRYCR	0.000e+0	65.97	Heat shock-like 85 kDa protein OS=Trypanosoma cruz...	[more]
sp\|P54651\|HSC90_DICDI	0.000e+0	64.34	Heat shock cognate 90 kDa protein OS=Dictyostelium...	[more]

BLAST of Heat shock protein 90 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
C0KTP7	0.000e+0	87.39	90 kDa heat shock protein OS=Dugesia japonica OX=6...	[more]
A0A3M7S7W0	0.000e+0	78.65	Heat shock 83 OS=Brachionus plicatilis OX=10195 GN...	[more]
A0A0M4HFL9	0.000e+0	79.86	Heat shock protein 90 OS=Macrostomum lignano OX=28...	[more]
A0A1C6ZXV8	0.000e+0	78.73	HSP90 OS=Cotesia chilonis OX=89804 GN=hsp90 PE=2 S...	[more]
A0A267DD20	0.000e+0	79.72	HATPase_c domain-containing protein OS=Macrostomum...	[more]

BLAST of Heat shock protein 90 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
hsp90aa1.2	1.089e-104	77.08	Astyanax mexicanus heat shock protein HSP 90-alpha...	[more]
hsp90aa1.2	1.089e-104	77.08	Astyanax mexicanus heat shock protein HSP 90-alpha...	[more]
hsp90ab1	1.009e-104	78.60	heat shock protein 90 alpha family class B member ...	[more]
hsp90aa1.2	1.334e-107	77.53	Astyanax mexicanus heat shock protein HSP 90-alpha...	[more]
hsp90aa1.2	2.133e-107	77.53	Astyanax mexicanus heat shock protein HSP 90-alpha...	[more]

BLAST of Heat shock protein 90 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 3


Match Name	E-value	Identity	Description
ENSPMAT00000003399.1	1.604e-83	76.70	pep scaffold:Pmarinus_7.0:GL479675:6143:15195:1 ge...	[more]
hsp90b1	1.458e-104	44.07	heat shock protein 90, beta (grp94), member 1 [Sou...	[more]
hsp90ab1	2.340e-63	65.57	heat shock protein 90, alpha (cytosolic), class A ...	[more]

BLAST of Heat shock protein 90 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 2


Match Name	E-value	Identity	Description
HSP82	0.000e+0	63.46	Hsp90 chaperone; redundant in function with Hsc82p...	[more]
HSC82	0.000e+0	61.38	Cytoplasmic chaperone of the Hsp90 family; plays a...	[more]

BLAST of Heat shock protein 90 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 3


Match Name	E-value	Identity	Description
HSP90	6.368e-104	79.73	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO45344	2.157e-112	48.79	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO45666	8.310e-45	44.61	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Heat shock protein 90 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
hsp90ab1	0.000e+0	74.86	heat shock protein 90 alpha family class B member ...	[more]
hsp90ab1	0.000e+0	73.17	heat shock protein 90 alpha family class B member ...	[more]
hsp90aa1.2	9.211e-106	78.88	heat shock protein HSP 90-alpha [Source:NCBI gene;...	[more]
hsp90aa1.2	8.293e-106	78.65	heat shock protein HSP 90-alpha [Source:NCBI gene;...	[more]
hsp90aa1.2	8.120e-106	78.43	heat shock protein HSP 90-alpha [Source:NCBI gene;...	[more]

BLAST of Heat shock protein 90 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000024822.1	0.000e+0	100.00	SMESG000024822.1	[more]
SMESG000071533.1	0.000e+0	90.34	SMESG000071533.1	[more]
SMESG000071531.1	6.376e-127	93.72	SMESG000071531.1	[more]
SMESG000025598.1	3.352e-114	86.00	SMESG000025598.1	[more]
SMESG000054819.1	9.843e-167	44.35	SMESG000054819.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30020317 ID=SMED30020317|Name=Heat shock protein 90|organism=Schmidtea mediterranea sexual|type=transcript|length=2308bp
TTACTATATTGTGTTCATAATTTAATATCAATTTAATGGAATCAATGAAT
GACTCTGAAACGTTTGCTTTTCAAGCTGAAATCGCACAATTATTGAGTCT
TATAATCAATACTTTCTATTCTAACAAAGAAATATTTTTGCGTGAATTAA
TTTCAAATTCTAGCGATGCACTAGACAAAATTCGATATAAAAGTTTGACA
GATCCGTCAGTACTCGACACTGCAAAGGAGTTAATCATAAAAATTATCCC
AGATAAAGATGCTGGAACTCTTACAATAATTGACACTGGAATTGGGATGA
CAAAGTCCGATTTGATTAATAATTTGGGTACAATTGCAAGATCAGGAACA
AAGGCATTTATGGAAGCACTGCAAGCTGGAGCTGATATTTCGATGATTGG
ACAATTTGGTGTTGGATTCTATTCATCGTATCTGGTAGCAGACAAAGTTC
AAGTTATATCAAAAGGTAATGATGACGAGCAATATTTATGGGAGTCTTCA
GCTGGTGGTTCTTTTACTATTAAACCTGATACATCAGAACCGTTAGGTCG
AGGATCTAAAATTATTCTGTTCATGAAAGAGGATCAAGTTGAATATTTAG
AAGAGCGCAAAATCAAAGAAATAATAAAAAAACATTCACAATTTATTGGT
TATCCAATTAAGCTTGTTCTTGAAAAAGAGCGTGACAAAGAAGTTTCGGA
CGATGAAGCTGAAACTGAAACTAAGAAAGAGGAAAGCGAAGAAGGTGAGG
ACAAGCCGAAAATTGAAGATTTGGATGATGAGGAAGATGACGATAAGAAA
GACAAGAAAAAGAAAAAGAAGATCAAAGAGAAATACATTGACGAGGAAGA
GCTGAATAAAACTAAACCAATTTGGACACGAAATCCCGATGATGTTAGTC
AAGAAGATTATGCTGAATTTTATAAATCCTTAACAAATGATTGGGAGGAT
CATTTAGCTGTGAAACATTTCTCTGTTGAAGGTCAATTGGAATTCCGTGC
ATTGTTATTTTGTCCTAAAAGAGCTCCTTTTGATTTGTTTGAAAACAAAA
AGAAAAGAAATAATATAAAACTCTACGTCCGTAGAGTGTTTATAATGGAC
AACTGTGAAGACTTGATACCGGAATATTTGAATTTTGTTAAAGGAGTAGT
CGACAGCGAAGATCTGCCATTGAATATCAGTCGAGAGATGCTTCAACAGA
ACAAGATTTTAAAAGTAATTCGTAAAAACTTGGTGAAAAAATGCCTGGAA
TTATTTGAAGAGATTATGGAAGACAAAGATAATTACAAAAAGTTTTATGA
ACAGTTCGCAAAGAATTTGAAGTTGGGAATTCACGAAGACAGCGTAAATC
GTAACAAATTGGCTGACTTCCTGCGCTACCATTCAACTTCAAGCGGTGAA
GAAATGACAAGTTTGAAGGATTACTTATCGAGAATGAAAGAAAATCAAAA
GGATATTTATTATATTACTGGGGAAAGTAAAGACAATGTAGCTCATTCGG
CATTCGTTGAGAGACTTACAAAGCGCGGGTTTGAGGTTCTGTATATGATC
GATCCAATTGACGAATACAGCGTTCAACAACTCAAGGAATATGACGGTAA
AAAACTGGTCTGTGTAACTAAAGAGGGATTGGAATTGCCGGAAGATGAAG
AGGAAAAGAAAAAATTTGAAGAACAAAAAGCTGCTTTTGAACCTCTGTGC
AAAGTTATGAAGGATATATTAGACAAAAAAGTTGAGAAAGTGACAGTTTC
GAACCGTTTGGTGTCTTCTCCATGCTGTATTGTAACTTCTCAGTTCGGTT
GGTCTGCCAATATGGAACGTATAATGAAAGCACAAGCGTTAAGAGACAGC
AGCACAATGGGATATATGGCTGCTAAAAAGCATTTAGAAATTAATCCAGA
TCACTCAGTTATGAAAGCTCTTAAAACAAGAGTCGATGCGGATAAAAATG
ATAAATCAGTTAAAGATTTGGTCATGCTTCTTTATGAAACTTCTTTATTA
AGCTCGGGATTTGCATTGGAAGATCCGCAGATTCATGCTAATCGGATTCA
TAGGATGATAAAACTGGGCCTCGGAATTGACGAAGATGACATGGAAATCG
ATACAACTGAAGTTGGTGATGTCCCGGTCGGTCCTTCGGCAACGGAAGAT
GAAGCTGGGAAAATGGAAGAAGTTGATTAAAAGAACTTTTTATTGTGTTG
TGTAAATATAATTTTTTATAGGATTATTTTGTAATAGGGTTATGAAGCAA
ATTAATTTTAATTTAATATCTTTTAATATGATATTTCTTTGCGTTATTTG
TATTTCCC

protein sequence of SMED30020317-orf-1

>SMED30020317-orf-1 ID=SMED30020317-orf-1|Name=SMED30020317-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=715bp
MESMNDSETFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIR
YKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTI
ARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKGNDDEQY
LWESSAGGSFTIKPDTSEPLGRGSKIILFMKEDQVEYLEERKIKEIIKKH
SQFIGYPIKLVLEKERDKEVSDDEAETETKKEESEEGEDKPKIEDLDDEE
DDDKKDKKKKKKIKEKYIDEEELNKTKPIWTRNPDDVSQEDYAEFYKSLT
NDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRR
VFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLV
KKCLELFEEIMEDKDNYKKFYEQFAKNLKLGIHEDSVNRNKLADFLRYHS
TSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFE
VLYMIDPIDEYSVQQLKEYDGKKLVCVTKEGLELPEDEEEKKKFEEQKAA
FEPLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQ
ALRDSSTMGYMAAKKHLEINPDHSVMKALKTRVDADKNDKSVKDLVMLLY
ETSLLSSGFALEDPQIHANRIHRMIKLGLGIDEDDMEIDTTEVGDVPVGP
SATEDEAGKMEEVD*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000026	gut
PLANA:0000028	Category 2 cell
PLANA:0000035	Category 3 cell
PLANA:0000043	dorsal ventral margin of the whole animal
PLANA:0000070	intestinal phagocyte
PLANA:0000099	neuron
PLANA:0000120	progenitor cell
PLANA:0000418	head
PLANA:0002032	epidermal cell
PLANA:0003116	parenchymal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR036890	HATPase_C_sf
IPR037196	HSP90_C
IPR020575	Hsp90_N
IPR003594	HATPase_C
IPR001404	Hsp90_fam
IPR019805	Heat_shock_protein_90_CS
IPR020568	Ribosomal_S5_D2-typ_fold

Vocabulary: **molecular function**
Term	Definition
GO:0005524	ATP binding
GO:0051082	unfolded protein binding
GO:0000166	nucleotide binding
GO:0016887	ATPase activity

Vocabulary: **biological process**
Term	Definition
GO:0006457	protein folding
GO:0006950	response to stress
GO:0009408	response to heat
GO:0009409	response to cold
GO:0046677	response to antibiotic

Vocabulary: **cellular component**
Term	Definition
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005886	plasma membrane
GO:0016020	membrane
GO:0042470	melanosome

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR020575	Heat shock protein Hsp90, N-terminal	PRINTS	PR00775	HEATSHOCK90	coord: 190..208 score: 63.56 coord: 78..95 score: 72.48 coord: 121..143 score: 80.13 coord: 8..28 score: 76.48 coord: 172..189 score: 58.03 coord: 96..113 score: 81.45 coord: 29..51 score: 90.64
IPR003594	Histidine kinase/HSP90-like ATPase	SMART	SM00387	HKATPase_4	coord: 30..168 e-value: 1.5E-7 score: 41.1
IPR003594	Histidine kinase/HSP90-like ATPase	PFAM	PF02518	HATPase_c	coord: 30..183 e-value: 1.2E-13 score: 51.6
IPR036890	Histidine kinase/HSP90-like ATPase superfamily	GENE3D	G3DSA:3.30.565.10		coord: 8..212 e-value: 4.3E-102 score: 342.7
IPR036890	Histidine kinase/HSP90-like ATPase superfamily	SUPERFAMILY	SSF55874	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	coord: 8..215
None	No IPR available	GENE3D	G3DSA:3.30.70.2140		coord: 213..262 e-value: 4.3E-102 score: 342.7
None	No IPR available	GENE3D	G3DSA:3.30.230.80		coord: 274..447 e-value: 3.6E-81 score: 273.0
None	No IPR available	GENE3D	G3DSA:3.40.50.11260		coord: 448..530 e-value: 6.5E-37 score: 127.2
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 217..257
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 695..714
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 217..238
None	No IPR available	PANTHER	PTHR11528:SF52	HEAT SHOCK PROTEIN HSP 90-ALPHA 1	coord: 6..714
None	No IPR available	CDD	cd16927	HATPase_Hsp90-like	coord: 18..204 e-value: 3.47399E-108 score: 324.474
IPR001404	Heat shock protein Hsp90 family	PFAM	PF00183	HSP90	coord: 186..691 e-value: 2.3E-234 score: 779.1
IPR001404	Heat shock protein Hsp90 family	PIRSF	PIRSF002583	HSP90_HTPG	coord: 1..714 e-value: 4.1E-251 score: 833.1
IPR001404	Heat shock protein Hsp90 family	PANTHER	PTHR11528	HEAT SHOCK PROTEIN 90 FAMILY MEMBER	coord: 6..714
IPR037196	HSP90, C-terminal domain	GENE3D	G3DSA:1.20.120.790		coord: 531..679 e-value: 1.3E-67 score: 228.2
IPR037196	HSP90, C-terminal domain	SUPERFAMILY	SSF110942	HSP90 C-terminal domain	coord: 553..675
IPR019805	Heat shock protein Hsp90, conserved site	PROSITE	PS00298	HSP90	coord: 28..37
IPR020568	Ribosomal protein S5 domain 2-type fold	SUPERFAMILY	SSF54211	Ribosomal protein S5 domain 2-like	coord: 275..530