Myophilin
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30020269 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 14
Homology
BLAST of Myophilin vs. Ensembl Human
Match: TAGLN3 (transgelin 3 [Source:HGNC Symbol;Acc:HGNC:29868]) HSP 1 Score: 92.8189 bits (229), Expect = 3.725e-22 Identity = 69/213 (32.39%), Postives = 104/213 (48.83%), Query Frame = 2
Query: 113 RAAKSGFAKDVQEKLAAQFDKSEAGKTLRWIKMLNATVPSHIKAAFDKIPTNIQECSMDEYHSFLFDGLVLGYLMAALDSGYSEQLNGKAWVISDKAIFETNRQRERIGIFLGFCSKYGLKSAFEFQTDQLFEQTNLNQVIVCLSQLGIEAQTKPN--YHGPKDYWMAKHQQNKREFTEEQLRSGESVIGLQMGTNKTANASGVS-FGAQRHI 742
R G +++VQEK+ ++D K + WI + A H + +L DG VL L+ +L E + + K F +Q E+I FL YG+++ FQT L+E ++ V L LG A TK + Y G ++ K QQN+R F+EEQLR G++VIGLQMG+NK A+ +G++ +G R I
Sbjct: 4 RGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPG------------RAHFQKWLMDGTVLCKLINSLYPPGQEPIPK---ISESKMAF---KQMEQISQFLKAAETYGVRTTDIFQTVDLWEGKDMAAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQMGSNKGASQAGMTGYGMPRQI 198
BLAST of Myophilin vs. Ensembl Human
Match: TAGLN3 (transgelin 3 [Source:HGNC Symbol;Acc:HGNC:29868]) HSP 1 Score: 92.8189 bits (229), Expect = 3.725e-22 Identity = 69/213 (32.39%), Postives = 104/213 (48.83%), Query Frame = 2
Query: 113 RAAKSGFAKDVQEKLAAQFDKSEAGKTLRWIKMLNATVPSHIKAAFDKIPTNIQECSMDEYHSFLFDGLVLGYLMAALDSGYSEQLNGKAWVISDKAIFETNRQRERIGIFLGFCSKYGLKSAFEFQTDQLFEQTNLNQVIVCLSQLGIEAQTKPN--YHGPKDYWMAKHQQNKREFTEEQLRSGESVIGLQMGTNKTANASGVS-FGAQRHI 742
R G +++VQEK+ ++D K + WI + A H + +L DG VL L+ +L E + + K F +Q E+I FL YG+++ FQT L+E ++ V L LG A TK + Y G ++ K QQN+R F+EEQLR G++VIGLQMG+NK A+ +G++ +G R I
Sbjct: 4 RGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPG------------RAHFQKWLMDGTVLCKLINSLYPPGQEPIPK---ISESKMAF---KQMEQISQFLKAAETYGVRTTDIFQTVDLWEGKDMAAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQMGSNKGASQAGMTGYGMPRQI 198
BLAST of Myophilin vs. Ensembl Human
Match: TAGLN3 (transgelin 3 [Source:HGNC Symbol;Acc:HGNC:29868]) HSP 1 Score: 92.8189 bits (229), Expect = 3.725e-22 Identity = 69/213 (32.39%), Postives = 104/213 (48.83%), Query Frame = 2
Query: 113 RAAKSGFAKDVQEKLAAQFDKSEAGKTLRWIKMLNATVPSHIKAAFDKIPTNIQECSMDEYHSFLFDGLVLGYLMAALDSGYSEQLNGKAWVISDKAIFETNRQRERIGIFLGFCSKYGLKSAFEFQTDQLFEQTNLNQVIVCLSQLGIEAQTKPN--YHGPKDYWMAKHQQNKREFTEEQLRSGESVIGLQMGTNKTANASGVS-FGAQRHI 742
R G +++VQEK+ ++D K + WI + A H + +L DG VL L+ +L E + + K F +Q E+I FL YG+++ FQT L+E ++ V L LG A TK + Y G ++ K QQN+R F+EEQLR G++VIGLQMG+NK A+ +G++ +G R I
Sbjct: 4 RGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPG------------RAHFQKWLMDGTVLCKLINSLYPPGQEPIPK---ISESKMAF---KQMEQISQFLKAAETYGVRTTDIFQTVDLWEGKDMAAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQMGSNKGASQAGMTGYGMPRQI 198
BLAST of Myophilin vs. Ensembl Human
Match: TAGLN3 (transgelin 3 [Source:HGNC Symbol;Acc:HGNC:29868]) HSP 1 Score: 92.8189 bits (229), Expect = 3.725e-22 Identity = 69/213 (32.39%), Postives = 104/213 (48.83%), Query Frame = 2
Query: 113 RAAKSGFAKDVQEKLAAQFDKSEAGKTLRWIKMLNATVPSHIKAAFDKIPTNIQECSMDEYHSFLFDGLVLGYLMAALDSGYSEQLNGKAWVISDKAIFETNRQRERIGIFLGFCSKYGLKSAFEFQTDQLFEQTNLNQVIVCLSQLGIEAQTKPN--YHGPKDYWMAKHQQNKREFTEEQLRSGESVIGLQMGTNKTANASGVS-FGAQRHI 742
R G +++VQEK+ ++D K + WI + A H + +L DG VL L+ +L E + + K F +Q E+I FL YG+++ FQT L+E ++ V L LG A TK + Y G ++ K QQN+R F+EEQLR G++VIGLQMG+NK A+ +G++ +G R I
Sbjct: 4 RGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPG------------RAHFQKWLMDGTVLCKLINSLYPPGQEPIPK---ISESKMAF---KQMEQISQFLKAAETYGVRTTDIFQTVDLWEGKDMAAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQMGSNKGASQAGMTGYGMPRQI 198
BLAST of Myophilin vs. Ensembl Human
Match: TAGLN (transgelin [Source:HGNC Symbol;Acc:HGNC:11553]) HSP 1 Score: 81.6481 bits (200), Expect = 4.979e-18 Identity = 62/217 (28.57%), Postives = 104/217 (47.93%), Query Frame = 2
Query: 128 GFAKDVQEKLAAQFDKSEAGKTLRWIKMLNATVPSHIKAAFDKIPTNIQECSMD---------EYHSFLFDGLVLGYLMAALDSGYSEQLNGKAWVISDKAIFETNRQRERIGIFLGFCSKYGLKSAFEFQTDQLFEQTNLNQVIVCLSQLGIEAQTKPN--YHGPKDYWMAKHQQNKREFTEEQLRSGESVIGLQMGTNKTANASGVS-FGAQRHI 742
G +++VQ K+ ++D+ + + WI I +C D + +L +G++L L+ +L S+ + + + +Q E++ FL YG+ FQT LFE ++ V L LG A TK + Y G +++M K Q++KREFTE QL+ G+ VIGLQMG+N+ A+ +G++ +G R I
Sbjct: 9 GMSREVQSKIEKKYDEELEERLVEWI---------------------IVQCGPDVGRPDRGRLGFQVWLKNGVILSKLVNSLYPDGSKPVK-----VPENPPSMVFKQMEQVAQFLKAAEDYGVIKTDMFQTVDLFEGKDMAAVQRTLMALGSLAVTKNDGHYRGDPNWFMKKAQEHKREFTESQLQEGKHVIGLQMGSNRGASQAGMTGYGRPRQI 199
BLAST of Myophilin vs. Ensembl Celegans
Match: cpn-1 (CPN-1; CalPoNin [Source:UniProtKB/TrEMBL;Acc:G5EFB5]) HSP 1 Score: 101.679 bits (252), Expect = 5.215e-26 Identity = 75/218 (34.40%), Postives = 116/218 (53.21%), Query Frame = 2
Query: 101 AQNYRAAKSGFAKDVQEKLAAQFDKSEAGKTLRWIKMLNATVPSHIKAAFDKIPTNIQECSMDEYHSFLFDGLVLGYLMAALDSGYSEQLNGKAWVISDKAIFETNRQRERIGIFLGFCSKYGLKSAFEFQTDQLFEQTNLNQVIVCLSQLGIEAQTKPNYH----GPKDYWMAKHQQNKREFTEEQLRSGESVIGLQMGTNKTANASGVSFGAQRHI 742
A + RA KSG A + Q+K+ ++DK+ AG+ L+W++ N T S FD + D DG +L L +L G +++N A ++ E I FL F +Y KS FQT L+E + N V++CL+ L +++ N+ GPK+ Q ++RE+T+EQL++G +VIGLQMG+NK A ASG++ G RH+
Sbjct: 5 ASSDRAEKSGIALEAQQKIYEKYDKNLAGEILQWVQ--NVTGQS-----FDT------QGDADNLVKVFQDGSLLCTLANSLKPGSVKKVNTSAMAF---------KKMENISFFLKFAEEYVQKSEL-FQTVDLYEGQDPNAVLICLASLA--RKSEKNFGRSGLGPKE-----AQGDRREWTDEQLKAGHNVIGLQMGSNKGATASGLNMGNTRHM 192
BLAST of Myophilin vs. Ensembl Celegans
Match: cpn-1 (CPN-1; CalPoNin [Source:UniProtKB/TrEMBL;Acc:G5EFB5]) HSP 1 Score: 101.679 bits (252), Expect = 5.215e-26 Identity = 75/218 (34.40%), Postives = 116/218 (53.21%), Query Frame = 2
Query: 101 AQNYRAAKSGFAKDVQEKLAAQFDKSEAGKTLRWIKMLNATVPSHIKAAFDKIPTNIQECSMDEYHSFLFDGLVLGYLMAALDSGYSEQLNGKAWVISDKAIFETNRQRERIGIFLGFCSKYGLKSAFEFQTDQLFEQTNLNQVIVCLSQLGIEAQTKPNYH----GPKDYWMAKHQQNKREFTEEQLRSGESVIGLQMGTNKTANASGVSFGAQRHI 742
A + RA KSG A + Q+K+ ++DK+ AG+ L+W++ N T S FD + D DG +L L +L G +++N A ++ E I FL F +Y KS FQT L+E + N V++CL+ L +++ N+ GPK+ Q ++RE+T+EQL++G +VIGLQMG+NK A ASG++ G RH+
Sbjct: 5 ASSDRAEKSGIALEAQQKIYEKYDKNLAGEILQWVQ--NVTGQS-----FDT------QGDADNLVKVFQDGSLLCTLANSLKPGSVKKVNTSAMAF---------KKMENISFFLKFAEEYVQKSEL-FQTVDLYEGQDPNAVLICLASLA--RKSEKNFGRSGLGPKE-----AQGDRREWTDEQLKAGHNVIGLQMGSNKGATASGLNMGNTRHM 192
BLAST of Myophilin vs. Ensembl Celegans
Match: cpn-1 (CPN-1; CalPoNin [Source:UniProtKB/TrEMBL;Acc:G5EFB5]) HSP 1 Score: 101.679 bits (252), Expect = 5.215e-26 Identity = 75/218 (34.40%), Postives = 116/218 (53.21%), Query Frame = 2
Query: 101 AQNYRAAKSGFAKDVQEKLAAQFDKSEAGKTLRWIKMLNATVPSHIKAAFDKIPTNIQECSMDEYHSFLFDGLVLGYLMAALDSGYSEQLNGKAWVISDKAIFETNRQRERIGIFLGFCSKYGLKSAFEFQTDQLFEQTNLNQVIVCLSQLGIEAQTKPNYH----GPKDYWMAKHQQNKREFTEEQLRSGESVIGLQMGTNKTANASGVSFGAQRHI 742
A + RA KSG A + Q+K+ ++DK+ AG+ L+W++ N T S FD + D DG +L L +L G +++N A ++ E I FL F +Y KS FQT L+E + N V++CL+ L +++ N+ GPK+ Q ++RE+T+EQL++G +VIGLQMG+NK A ASG++ G RH+
Sbjct: 5 ASSDRAEKSGIALEAQQKIYEKYDKNLAGEILQWVQ--NVTGQS-----FDT------QGDADNLVKVFQDGSLLCTLANSLKPGSVKKVNTSAMAF---------KKMENISFFLKFAEEYVQKSEL-FQTVDLYEGQDPNAVLICLASLA--RKSEKNFGRSGLGPKE-----AQGDRREWTDEQLKAGHNVIGLQMGSNKGATASGLNMGNTRHM 192
BLAST of Myophilin vs. Ensembl Celegans
Match: cpn-2 (Transgelin [Source:UniProtKB/TrEMBL;Acc:A0A0K3AWU9]) HSP 1 Score: 79.337 bits (194), Expect = 1.490e-17 Identity = 66/208 (31.73%), Postives = 99/208 (47.60%), Query Frame = 2
Query: 128 GFAKDVQEKLAAQFDKSEAGKTLRWIKMLNATVPSHIKAAFDKIPTNIQEC-SMDEYHSFLFDGLVLGYLMAALDSGYSEQLNGKAWVISDKAIFETNRQRERIGIFLGFCSKYGLKSAFEFQTDQLFEQTNLNQVIVCLSQLGIEAQTKPNYHGPKDYWMAK-HQQNKREFTEEQLRSGESVIGLQMGTNKTANASGVS-FGAQRHI 742
G ++++Q+K A+F EA + L+WI+ + + +FD + C S + + L DG++L L+ LD N K K F E I FL ++G+ FQT L+E +VI CL L AQ++ + H W+ K Q + R+F E +R GE VI LQ GTNK A+ G+S +G R I
Sbjct: 9 GLSRELQKKNDARFVLEEAIEVLKWIENVTGE-----RFSFD-----VTTCESSTDVSNLLKDGVMLCKLIEKLDPSCRVVYNKKP-----KMAFPM---MENISNFLAAAKQFGVMEISCFQTVDLYENKQCYKVIECLRLLAAVAQSR-SSHLEHPAWVVKLAQSSPRQFPEAVMRRGEMVIPLQYGTNKCASQKGMSPYGLPRQI 197
BLAST of Myophilin vs. Ensembl Celegans
Match: cpn-2 (Transgelin [Source:UniProtKB/TrEMBL;Acc:A0A0K3AWU9]) HSP 1 Score: 79.337 bits (194), Expect = 1.490e-17 Identity = 66/208 (31.73%), Postives = 99/208 (47.60%), Query Frame = 2
Query: 128 GFAKDVQEKLAAQFDKSEAGKTLRWIKMLNATVPSHIKAAFDKIPTNIQEC-SMDEYHSFLFDGLVLGYLMAALDSGYSEQLNGKAWVISDKAIFETNRQRERIGIFLGFCSKYGLKSAFEFQTDQLFEQTNLNQVIVCLSQLGIEAQTKPNYHGPKDYWMAK-HQQNKREFTEEQLRSGESVIGLQMGTNKTANASGVS-FGAQRHI 742
G ++++Q+K A+F EA + L+WI+ + + +FD + C S + + L DG++L L+ LD N K K F E I FL ++G+ FQT L+E +VI CL L AQ++ + H W+ K Q + R+F E +R GE VI LQ GTNK A+ G+S +G R I
Sbjct: 9 GLSRELQKKNDARFVLEEAIEVLKWIENVTGE-----RFSFD-----VTTCESSTDVSNLLKDGVMLCKLIEKLDPSCRVVYNKKP-----KMAFPM---MENISNFLAAAKQFGVMEISCFQTVDLYENKQCYKVIECLRLLAAVAQSR-SSHLEHPAWVVKLAQSSPRQFPEAVMRRGEMVIPLQYGTNKCASQKGMSPYGLPRQI 197
BLAST of Myophilin vs. Ensembl Fly
Match: Chd64 (gene:FBgn0035499 transcript:FBtr0073270) HSP 1 Score: 112.849 bits (281), Expect = 3.400e-30 Identity = 78/217 (35.94%), Postives = 114/217 (52.53%), Query Frame = 2
Query: 98 MAQNYRAAKSGFAKDVQEKLAAQFDKSEAGKTLRWIKMLNATVPSHIKAAFDKIPTNIQECSMDEYHSFLFDGLVLGYLMAALDSGYSEQLNGKAWVISDKAIFETNRQRERIGIFLGFCSKYGLKSAFEFQTDQLFEQTNLNQVIVCLSQLGIEAQT--KPNYHGPKDYWMAKHQQNKREFTEEQLRSGESVIGLQMGTNKTANASGVSFGAQRHI 742
MA N RAAKSGFA + Q K+ +++ + A ++L WIK A I + D D + L DG++L L AL G +++N K F+ E I FL +G+ + FQ+ L+E+ NLN V++CL LG +A KP+ GPK+ +N R F++EQLR+G +VI LQ G+NK A SG++FG RH+
Sbjct: 1 MASN-RAAKSGFAAEAQRKINSKYSEELAQESLEWIK---AVTEEPINTSGD----------TDNFFEVLKDGVILCKLANALQPGSIKKIN------ESKMAFKC---MENISAFLACAKNFGVPTQETFQSVDLWERQNLNSVVICLQSLGRKASNFNKPSI-GPKE-----ADKNVRNFSDEQLRAGANVISLQYGSNKGATQSGINFGNTRHM 188
BLAST of Myophilin vs. Ensembl Fly
Match: Chd64 (gene:FBgn0035499 transcript:FBtr0310531) HSP 1 Score: 96.2857 bits (238), Expect = 4.773e-24 Identity = 67/201 (33.33%), Postives = 102/201 (50.75%), Query Frame = 2
Query: 146 QEKLAAQFDKSEAGKTLRWIKMLNATVPSHIKAAFDKIPTNIQECSMDEYHSFLFDGLVLGYLMAALDSGYSEQLNGKAWVISDKAIFETNRQRERIGIFLGFCSKYGLKSAFEFQTDQLFEQTNLNQVIVCLSQLGIEAQT--KPNYHGPKDYWMAKHQQNKREFTEEQLRSGESVIGLQMGTNKTANASGVSFGAQRHI 742
Q K+ +++ + A ++L WIK A I + D D + L DG++L L AL G +++N K F+ E I FL +G+ + FQ+ L+E+ NLN V++CL LG +A KP+ GPK+ +N R F++EQLR+G +VI LQ G+NK A SG++FG RH+
Sbjct: 3 QSKINSKYSEELAQESLEWIK---AVTEEPINTSGD----------TDNFFEVLKDGVILCKLANALQPGSIKKIN------ESKMAFKC---MENISAFLACAKNFGVPTQETFQSVDLWERQNLNSVVICLQSLGRKASNFNKPSI-GPKE-----ADKNVRNFSDEQLRAGANVISLQYGSNKGATQSGINFGNTRHM 175
BLAST of Myophilin vs. Ensembl Fly
Match: CG5023 (gene:FBgn0038774 transcript:FBtr0083866) HSP 1 Score: 70.4774 bits (171), Expect = 1.349e-14 Identity = 59/167 (35.33%), Postives = 79/167 (47.31%), Query Frame = 2
Query: 251 DKIPTNIQECSMDEYHSFLFDGLVLGYLMAALDSGYSEQLNGKAWVISDKAIFETNRQ-RERIGIFLGFCSKYGLKSAFEFQTDQLFEQTNLNQVIVCLSQLGIEAQTKPNYHGPK-DYWMAKHQQNKREFTEEQLRSGESVIGLQMGTNKTANASG-VSFGAQRHI 742
+K+P+ +Y L DG+ L L L G +++ + TN Q E I F KYG+ FQT LFE+ N+ QV + L LG Q P Y GP MA +N+R FTEEQLR+ E + LQMG NK A+ +G G RH+
Sbjct: 22 EKVPSG-------QYEDILKDGIWLCKLANKLAPGSVKKIQERG----------TNFQLMENIQRFQAAVKKYGVPEEEIFQTADLFERRNIPQVTLSLYALGRITQKHPEYTGPTLGPKMA--DKNERSFTEEQLRAHEGELNLQMGFNKGASQAGHGGMGNTRHM 169
BLAST of Myophilin vs. Ensembl Fly
Match: Mp20 (gene:FBgn0002789 transcript:FBtr0087745) HSP 1 Score: 64.3142 bits (155), Expect = 2.884e-12 Identity = 46/151 (30.46%), Postives = 71/151 (47.02%), Query Frame = 2
Query: 293 YHSFLFDGLVLGYLMAALDSGYSEQLNGKAWVISDKAIFETNRQRERIGIFLGFCSKYGLKSAFEFQTDQLFEQTNLNQVIVCLSQLGIEAQTKPNYHGPKDYWMAKH-QQNKREFTEEQLRSGESVIGLQMGTNKTANASGVSFGAQRHI 742
Y L DG VL L+ L ++N + E I F +YG+ FQT L+E+ ++ V + LG ++ GP + K + KR+FTEEQL++G++++GLQ G+NK A +G + GA R I
Sbjct: 41 YEDVLKDGQVLCKLINVLSPNAVPKVNSSGGQF---------KFMENINNFQKALKEYGVPDIDVFQTVDLYEKKDIANVTNTIFALGRATYKHADFKGP--FLGPKPADECKRDFTEEQLKAGQTIVGLQAGSNKGATQAGQNLGAGRKI 180
BLAST of Myophilin vs. Ensembl Fly
Match: Mp20 (gene:FBgn0002789 transcript:FBtr0345532) HSP 1 Score: 64.6994 bits (156), Expect = 2.962e-12 Identity = 46/151 (30.46%), Postives = 71/151 (47.02%), Query Frame = 2
Query: 293 YHSFLFDGLVLGYLMAALDSGYSEQLNGKAWVISDKAIFETNRQRERIGIFLGFCSKYGLKSAFEFQTDQLFEQTNLNQVIVCLSQLGIEAQTKPNYHGPKDYWMAKH-QQNKREFTEEQLRSGESVIGLQMGTNKTANASGVSFGAQRHI 742
Y L DG VL L+ L ++N + E I F +YG+ FQT L+E+ ++ V + LG ++ GP + K + KR+FTEEQL++G++++GLQ G+NK A +G + GA R I
Sbjct: 41 YEDVLKDGQVLCKLINVLSPNAVPKVNSSGGQF---------KFMENINNFQKALKEYGVPDIDVFQTVDLYEKKDIANVTNTIFALGRATYKHADFKGP--FLGPKPADECKRDFTEEQLKAGQTIVGLQAGSNKGATQAGQNLGAGRKI 180
BLAST of Myophilin vs. Ensembl Zebrafish
Match: tagln3a (transgelin 3a [Source:ZFIN;Acc:ZDB-GENE-060531-53]) HSP 1 Score: 94.7449 bits (234), Expect = 5.373e-23 Identity = 69/213 (32.39%), Postives = 104/213 (48.83%), Query Frame = 2
Query: 113 RAAKSGFAKDVQEKLAAQFDKSEAGKTLRWIKMLNATVPSHIKAAFDKIPTNIQECSMDEYHSFLFDGLVLGYLMAALDSGYSEQLNGKAWVISDKAIFETNRQRERIGIFLGFCSKYGLKSAFEFQTDQLFEQTNLNQVIVCLSQLGIEAQTKPN--YHGPKDYWMAKHQQNKREFTEEQLRSGESVIGLQMGTNKTANASG-VSFGAQRHI 742
R G +++VQEK+ ++D + + WI I+ D E + +L G +L L+ +L E + + K +F +Q E+I FL F +YG+ FQT L+E ++ V L LG EA TK + Y G D++ K + +KREF+EEQLR G VIG+QMG+N+ A+ SG V +G R I
Sbjct: 4 RGPSYGLSREVQEKIDQKYDAELESRLVDWI---------LIQCGDD---LQRPEPGKQNFQKWLMSGTILCRLINSLYPSGEEPIKK---ITESKMVF---KQMEKISQFLQFAEEYGVNRGDIFQTVDLWEGKDMAAVQRTLMALGSEALTKDDGHYRGDPDWFHRKTKGHKREFSEEQLRQGRVVIGMQMGSNRGASQSGMVGYGTPRQI 198
BLAST of Myophilin vs. Ensembl Zebrafish
Match: tagln2 (transgelin 2 [Source:ZFIN;Acc:ZDB-GENE-020802-2]) HSP 1 Score: 92.4337 bits (228), Expect = 4.706e-22 Identity = 69/225 (30.67%), Postives = 114/225 (50.67%), Query Frame = 2
Query: 92 LTMAQNYRAAKSGFAKDVQEKLAAQFDKSEAGKTLRWIKMLNATVPSHIKAAFDKIPTNIQECSMDEYHSFLFDGLVLGYLMAAL--DSGYSEQLNGKAWVISDKAIFETNRQRERIGIFLGFCSKYGLKSAFEFQTDQLFEQTNLNQVIVCLSQLGIEAQTKPN--YHGPKDYWMAKHQQNKREFTEEQLRSGESVIGLQMGTNKTANASGVS-FGAQRHITDS 751
+T+ + G +++VQ K+ ++D G+ ++WI S A K Q + +L DG +L L+ +L DS +++ + +Q E+I FL +YG+ + FQT L+E +L V + L LG A TK + Y G ++ K Q+N+REF+EEQ++ G+SVIGLQMGTNK A+ +G++ +G R I ++
Sbjct: 12 MTVKMANKGPSYGLSREVQSKIDKKYDPELEGRLVQWIV-------SQCGEAIGKPQPGKQG-----FQQWLKDGCILCELINSLFKDSKPVKKIQSSSMAF---------KQMEQISQFLTAAERYGITKSDIFQTVDLWEGKDLAAVQMTLLSLGSLAVTKDDGCYRGDPAWFPKKSQENRREFSEEQMKEGQSVIGLQMGTNKGASQAGMTGYGRPRQILNN 215
BLAST of Myophilin vs. Ensembl Zebrafish
Match: tagln2 (transgelin 2 [Source:ZFIN;Acc:ZDB-GENE-020802-2]) HSP 1 Score: 91.2781 bits (225), Expect = 9.073e-22 Identity = 68/213 (31.92%), Postives = 110/213 (51.64%), Query Frame = 2
Query: 128 GFAKDVQEKLAAQFDKSEAGKTLRWIKMLNATVPSHIKAAFDKIPTNIQECSMDEYHSFLFDGLVLGYLMAAL--DSGYSEQLNGKAWVISDKAIFETNRQRERIGIFLGFCSKYGLKSAFEFQTDQLFEQTNLNQVIVCLSQLGIEAQTKPN--YHGPKDYWMAKHQQNKREFTEEQLRSGESVIGLQMGTNKTANASGVS-FGAQRHITDS 751
G +++VQ K+ ++D G+ ++WI S A K Q + +L DG +L L+ +L DS +++ + +Q E+I FL +YG+ + FQT L+E +L V + L LG A TK + Y G ++ K Q+N+REF+EEQ++ G+SVIGLQMGTNK A+ +G++ +G R I ++
Sbjct: 9 GLSREVQSKIDKKYDPELEGRLVQWIV-------SQCGEAIGKPQPGKQG-----FQQWLKDGCILCELINSLFKDSKPVKKIQSSSMAF---------KQMEQISQFLTAAERYGITKSDIFQTVDLWEGKDLAAVQMTLLSLGSLAVTKDDGCYRGDPAWFPKKSQENRREFSEEQMKEGQSVIGLQMGTNKGASQAGMTGYGRPRQILNN 200
BLAST of Myophilin vs. Ensembl Zebrafish
Match: tagln2 (transgelin 2 [Source:ZFIN;Acc:ZDB-GENE-020802-2]) HSP 1 Score: 91.2781 bits (225), Expect = 9.073e-22 Identity = 68/213 (31.92%), Postives = 110/213 (51.64%), Query Frame = 2
Query: 128 GFAKDVQEKLAAQFDKSEAGKTLRWIKMLNATVPSHIKAAFDKIPTNIQECSMDEYHSFLFDGLVLGYLMAAL--DSGYSEQLNGKAWVISDKAIFETNRQRERIGIFLGFCSKYGLKSAFEFQTDQLFEQTNLNQVIVCLSQLGIEAQTKPN--YHGPKDYWMAKHQQNKREFTEEQLRSGESVIGLQMGTNKTANASGVS-FGAQRHITDS 751
G +++VQ K+ ++D G+ ++WI S A K Q + +L DG +L L+ +L DS +++ + +Q E+I FL +YG+ + FQT L+E +L V + L LG A TK + Y G ++ K Q+N+REF+EEQ++ G+SVIGLQMGTNK A+ +G++ +G R I ++
Sbjct: 9 GLSREVQSKIDKKYDPELEGRLVQWIV-------SQCGEAIGKPQPGKQG-----FQQWLKDGCILCELINSLFKDSKPVKKIQSSSMAF---------KQMEQISQFLTAAERYGITKSDIFQTVDLWEGKDLAAVQMTLLSLGSLAVTKDDGCYRGDPAWFPKKSQENRREFSEEQMKEGQSVIGLQMGTNKGASQAGMTGYGRPRQILNN 200
BLAST of Myophilin vs. Ensembl Zebrafish
Match: tagln3b (transgelin 3b [Source:ZFIN;Acc:ZDB-GENE-030131-4199]) HSP 1 Score: 88.1965 bits (217), Expect = 9.293e-21 Identity = 70/219 (31.96%), Postives = 106/219 (48.40%), Query Frame = 2
Query: 113 RAAKSGFAKDVQEKLAAQFDKSEAGKTLRWIKML---NATVPSHIKAAFDKIPTNIQECSMDEYHSFLFDGLVLGYLMAALDSGYSEQLNGKAWVISDKAIFETN---RQRERIGIFLGFCSKYGLKSAFEFQTDQLFEQTNLNQVIVCLSQLGIEAQTKPN--YHGPKDYWMAKHQQNKREFTEEQLRSGESVIGLQMGTNKTANASGVS-FGAQRHI 742
R G +++VQEK+ ++D + WI N P K F ++L DG +L L+ +L E + K I ET +Q E+I FL YG+ + FQT L+E ++ V L LG A TK + Y G ++++ K Q N+REF+EEQLR G+++IGLQMG+N+ A+ SG++ +G R I
Sbjct: 4 RGPSYGLSREVQEKIEQKYDPELESRLEDWIVAQCGGNVEKPQPGKQNF---------------QNWLMDGTILCRLINSLYPRGKEPI---------KKISETQMAFKQMEKISQFLQAAEAYGVITTDIFQTVDLWEGKDMAAVQRTLMALGSVAITKDDGQYRGNREWFHRKSQGNRREFSEEQLRQGQNLIGLQMGSNRGASQSGMTGYGMHRQI 198
BLAST of Myophilin vs. Ensembl Xenopus
Match: tagln2 (transgelin 2 [Source:NCBI gene;Acc:394981]) HSP 1 Score: 92.0485 bits (227), Expect = 5.044e-22 Identity = 65/208 (31.25%), Postives = 112/208 (53.85%), Query Frame = 2
Query: 128 GFAKDVQEKLAAQFDKSEAGKTLRWIKMLNATVPSHIKAAFDKIPTNIQECSMDEYHSFLFDGLVLGYLMAALDSGYSEQLNGKAWVISDKAIFETNRQRERIGIFLGFCSKYGLKSAFEFQTDQLFEQTNLNQVIVCLSQLGIEAQTKPN--YHGPKDYWMAKHQQNKREFTEEQLRSGESVIGLQMGTNKTANASGVS-FGAQRHI 742
G +++VQ+K+ ++D ++WIK A +H + + + +Q +L DG VL +L+ +L G ++ A +Q E+I FL C +YG+ ++ FQT L+E ++ V L LG A TK + + G +++ K Q+NKREF++++L+ G+++IGLQMGTNK A+ SG++ +G R I
Sbjct: 9 GLSREVQQKIDQKYDNDLETILVQWIK---AQCGTHAGSFDGQGKSAVQ--------VWLKDGTVLSHLINSLAPGSIAKVQTSAMAF---------KQMEQISQFLKACERYGIPASDLFQTVDLWEGKDMASVQRTLMNLGGIAVTKGDGYFRGDPNWFPKKSQENKREFSQDKLKEGQNIIGLQMGTNKGASQSGMTGYGMPRQI 196
BLAST of Myophilin vs. Ensembl Xenopus
Match: tfdp1 (transcription factor Dp-1 [Source:Xenbase;Acc:XB-GENE-1219073]) HSP 1 Score: 84.7297 bits (208), Expect = 2.501e-18 Identity = 63/221 (28.51%), Postives = 107/221 (48.42%), Query Frame = 2
Query: 98 MAQNYRAAKSGFAKDVQEKLAAQFDKSEAGKTLRWIKMLNATVPSHIKAAFDKIPTNIQECSMDEYHSFLFDGLVLGYLMAALDSGYSEQLNGKA--WVISDKAIFETNRQRERIGIFLGFCSKYGLKSAFEFQTDQLFEQTNLNQVIVCLSQLGIEAQTKPNYHGPKDYWMAKHQQNKREFTEEQLRSGESVIGLQMGTNKTANASGVS-FGAQRHITDS 751
MA + G + +V+ K+A ++D + WI+ + + I N Q+ L DG++L L+ L G +++N W + E IG F+ YG+K F+ + LFE N+ QV L L A+T+ +H D + ++ KR+F +E++++G+SVIGLQMGTNK A+ +G++ +G +RH+ D
Sbjct: 1 MANFNKGPAYGLSAEVKNKIAQKYDPQVEEELRLWIEEVTGMI----------IGENFQQG--------LRDGIILCNLINKLQPGSIKKINEAKLNW-----------HKLENIGNFIKAMQDYGMKPHDIFEANDLFENGNMTQVQTSLVSLAGLAKTR-GFHTSVDIGVKYAEKQKRQFGDEKMKAGQSVIGLQMGTNKCASQAGMTAYGTRRHLYDP 191
BLAST of Myophilin vs. Ensembl Xenopus
Match: kcnb2 (potassium channel, voltage gated Shab related subfamily B, member 2 [Source:Xenbase;Acc:XB-GENE-989392]) HSP 1 Score: 81.2629 bits (199), Expect = 6.985e-18 Identity = 59/211 (27.96%), Postives = 105/211 (49.76%), Query Frame = 2
Query: 128 GFAKDVQEKLAAQFDKSEAGKTLRWIKML---NATVPSHIKAAFDKIPTNIQECSMDEYHSFLFDGLVLGYLMAALDSGYSEQLNGKAWVISDKAIFETNRQRERIGIFLGFCSKYGLKSAFEFQTDQLFEQTNLNQVIVCLSQLGIEAQTKPN--YHGPKDYWMAKHQQNKREFTEEQLRSGESVIGLQMGTNKTANASGVS-FGAQRHI 742
G +++VQ ++ ++D+ + ++WI + + P + F +L +GLVL L+ +L S+ + I D +Q E++ FL YG+ FQT L+E ++ V + LG A TK + Y G ++M K Q++KR+F++E+L+ G+++IGLQMG+N+ A SG++ +G R I
Sbjct: 15 GMSREVQSRIEKKYDEELEQRLVQWICIQCGDDVGTPEQGRLGF---------------QQWLKNGLVLSKLINSLYPKGSQPVK-----IPDPPPSMVFKQMEQVAQFLRASEDYGVVKTDMFQTVDLYEGKDMAAVQRTIVALGSIAVTKNDGQYKGDPSWFMKKAQEHKRDFSDEKLKEGKNIIGLQMGSNQGATQSGMTGYGRPRQI 205
BLAST of Myophilin vs. Ensembl Xenopus
Match: kcnb2 (potassium channel, voltage gated Shab related subfamily B, member 2 [Source:Xenbase;Acc:XB-GENE-989392]) HSP 1 Score: 80.8777 bits (198), Expect = 7.372e-18 Identity = 59/211 (27.96%), Postives = 105/211 (49.76%), Query Frame = 2
Query: 128 GFAKDVQEKLAAQFDKSEAGKTLRWIKML---NATVPSHIKAAFDKIPTNIQECSMDEYHSFLFDGLVLGYLMAALDSGYSEQLNGKAWVISDKAIFETNRQRERIGIFLGFCSKYGLKSAFEFQTDQLFEQTNLNQVIVCLSQLGIEAQTKPN--YHGPKDYWMAKHQQNKREFTEEQLRSGESVIGLQMGTNKTANASGVS-FGAQRHI 742
G +++VQ ++ ++D+ + ++WI + + P + F +L +GLVL L+ +L S+ + I D +Q E++ FL YG+ FQT L+E ++ V + LG A TK + Y G ++M K Q++KR+F++E+L+ G+++IGLQMG+N+ A SG++ +G R I
Sbjct: 9 GMSREVQSRIEKKYDEELEQRLVQWICIQCGDDVGTPEQGRLGF---------------QQWLKNGLVLSKLINSLYPKGSQPVK-----IPDPPPSMVFKQMEQVAQFLRASEDYGVVKTDMFQTVDLYEGKDMAAVQRTIVALGSIAVTKNDGQYKGDPSWFMKKAQEHKRDFSDEKLKEGKNIIGLQMGSNQGATQSGMTGYGRPRQI 199
BLAST of Myophilin vs. Ensembl Xenopus
Match: slc5a8.1 (solute carrier family 5 member 8, gene 1 [Source:Xenbase;Acc:XB-GENE-479634]) HSP 1 Score: 77.411 bits (189), Expect = 6.483e-16 Identity = 63/210 (30.00%), Postives = 100/210 (47.62%), Query Frame = 2
Query: 128 GFAKDVQEKLAAQFDKSEAGKTLRWIKMLNATVPSHIKAAFDKIPTNIQECSMDEYHSFLFDGLVLGYLMAALDSGYSEQLN--GKAWVISDKAIFETNRQRERIGIFLGFCSKYGLKSAFEFQTDQLFEQTNLNQVIVCLSQLGIEAQTKPNYHGPKDYWMAKHQQNKREFTEEQLRSGESVIGLQMGTNKTANASGV-SFGAQRHITD 748
G + +V+ KLA ++D + + WI+ L I F MD L DG++L L+ L G ++N + W + E IG F+ ++YG+K F+ + LFE TNL QV L L A+TK D + + +R++ ++L+ G ++IGLQMGTNK A+ G+ S+G +RH+ D
Sbjct: 12 GLSAEVKNKLAQKYDVQKEAELREWIEGLTGRT---IGKGF-----------MDS----LKDGIILCELINKLQPGTVRKINEATQNW-----------HKLENIGNFIKGITQYGVKPHDIFEANDLFENTNLTQVQYTLLALASVAKTK---GATVDIGVKYADRQERKYDLDKLKEGRNIIGLQMGTNKYASQKGMTSYGTRRHLYD 189
BLAST of Myophilin vs. Ensembl Mouse
Match: Tagln3 (transgelin 3 [Source:MGI Symbol;Acc:MGI:1926784]) HSP 1 Score: 92.0485 bits (227), Expect = 3.679e-22 Identity = 69/213 (32.39%), Postives = 104/213 (48.83%), Query Frame = 2
Query: 113 RAAKSGFAKDVQEKLAAQFDKSEAGKTLRWIKMLNATVPSHIKAAFDKIPTNIQECSMDEYHSFLFDGLVLGYLMAALDSGYSEQLNGKAWVISDKAIFETNRQRERIGIFLGFCSKYGLKSAFEFQTDQLFEQTNLNQVIVCLSQLGIEAQTKPN--YHGPKDYWMAKHQQNKREFTEEQLRSGESVIGLQMGTNKTANASGVS-FGAQRHI 742
R G +++VQEK+ ++D K + WI + A H + +L DG VL L+ +L E + + K F +Q E+I FL YG+++ FQT L+E ++ V L LG A TK + Y G ++ K QQN+R F+EEQLR G++VIGLQMG+NK A+ +G++ +G R I
Sbjct: 4 RGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPG------------RAHFQKWLMDGTVLCKLINSLYPPGQEPIPK---ISESKMAF---KQMEQISQFLKAAEVYGVRTTDIFQTVDLWEGKDMAAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQMGSNKGASQAGMTGYGMPRQI 198
BLAST of Myophilin vs. Ensembl Mouse
Match: Cnn3 (calponin 3, acidic [Source:MGI Symbol;Acc:MGI:1919244]) HSP 1 Score: 83.5741 bits (205), Expect = 4.689e-18 Identity = 64/215 (29.77%), Postives = 103/215 (47.91%), Query Frame = 2
Query: 113 RAAKSGFAKDVQEKLAAQFDKSEAGKTLRWIKMLNATVPSHIKAAFDKIPTNIQECSMDEYHSFLFDGLVLGYLMAALDSGYSEQLNGKA--WVISDKAIFETNRQRERIGIFLGFCSKYGLKSAFEFQTDQLFEQTNLNQVIVCLSQLGIEAQTKPNYHGPKDYWMAKHQQNKREFTEEQLRSGESVIGLQMGTNKTANASGVS-FGAQRHITD 748
+ G + +V+ K+A+++D+ WI+ + I TN Q L DG++L L+ L G +++N + W Q E IG F+ YG+K F+ + LFE N+ QV L L A+TK +H D + ++ R F E +L++G+SVIGLQMGTNK A+ +G++ +G +RH+ D
Sbjct: 6 KGPSYGLSAEVKNKIASKYDQQAEEDLRNWIEEVTGL----------GIGTNFQLG--------LKDGIILCELINKLQPGSVKKVNESSLNW-----------PQLENIGNFIKAIQAYGMKPHDIFEANDLFENGNMTQVQTTLVALAGLAKTK-GFHTTIDIGVKYAEKQTRRFDEGKLKAGQSVIGLQMGTNKCASQAGMTAYGTRRHLYD 190
BLAST of Myophilin vs. Ensembl Mouse
Match: Tagln (transgelin [Source:MGI Symbol;Acc:MGI:106012]) HSP 1 Score: 80.8777 bits (198), Expect = 6.311e-18 Identity = 61/211 (28.91%), Postives = 104/211 (49.29%), Query Frame = 2
Query: 128 GFAKDVQEKLAAQFDKSEAGKTLRWIKM---LNATVPSHIKAAFDKIPTNIQECSMDEYHSFLFDGLVLGYLMAALDSGYSEQLNGKAWVISDKAIFETNRQRERIGIFLGFCSKYGLKSAFEFQTDQLFEQTNLNQVIVCLSQLGIEAQTK--PNYHGPKDYWMAKHQQNKREFTEEQLRSGESVIGLQMGTNKTANASGVS-FGAQRHI 742
G +++VQ K+ ++D+ + + WI + + P + F +L +G++L L+ +L Y E K + + +Q E++ FL YG+ FQT L+E ++ V L LG A TK NY G +++M K Q++KR+FT+ QL+ G+ VIGLQMG+N+ A+ +G++ +G R I
Sbjct: 9 GMSREVQSKIEKKYDEELEERLVEWIVVQCGPDVGRPDRGRLGF---------------QVWLKNGVILSKLVNSL---YPE--GSKPVKVPENPPSMVFKQMEQVAQFLKAAEDYGVIKTDMFQTVDLYEGKDMAAVQRTLMALGSLAVTKNDGNYRGDPNWFMKKAQEHKRDFTDSQLQEGKHVIGLQMGSNRGASQAGMTGYGRPRQI 199
BLAST of Myophilin vs. Ensembl Mouse
Match: Tagln2 (transgelin 2 [Source:MGI Symbol;Acc:MGI:1312985]) HSP 1 Score: 78.9518 bits (193), Expect = 3.069e-17 Identity = 62/213 (29.11%), Postives = 107/213 (50.23%), Query Frame = 2
Query: 113 RAAKSGFAKDVQEKLAAQFDKSEAGKTLRWIKMLNATVPSHIKAAFDKIPTNIQECSMDEYHSFLFDGLVLGYLMAALDSGYSEQLNGKAWVISDKAIFETNRQRERIGIFLGFCSKYGLKSAFEFQTDQLFEQTNLNQVIVCLSQLGIEAQTKPN--YHGPKDYWMAKHQQNKREFTEEQLRSGESVIGLQMGTNKTANASGVS-FGAQRHI 742
R G +++VQ+K+ Q+D ++WI + + + + + + +L DG VL L+ +L Y E G+A V +A +Q E+I FL +YG+ + FQT L+E N+ V L LG A + + + G +++ K ++N R F++ QL+ G++VIGLQMGTN+ A+ +G++ +G R I
Sbjct: 4 RGPSYGLSREVQQKIEKQYDADLEQILIQWIT-------TQCREDVGQ-----PQPGRENFQKWLKDGTVLCKLINSL---YPE---GQAPVKKIQASSMAFKQMEQISQFLQAAERYGINTTDIFQTVDLWEGKNMACVQRTLMNLGGLAVARDDGLFSGDPNWFPKKSKENPRNFSDNQLQEGKNVIGLQMGTNRGASQAGMTGYGMPRQI 198
BLAST of Myophilin vs. Ensembl Mouse
Match: Tagln2 (transgelin 2 [Source:MGI Symbol;Acc:MGI:1312985]) HSP 1 Score: 78.9518 bits (193), Expect = 3.069e-17 Identity = 62/213 (29.11%), Postives = 107/213 (50.23%), Query Frame = 2
Query: 113 RAAKSGFAKDVQEKLAAQFDKSEAGKTLRWIKMLNATVPSHIKAAFDKIPTNIQECSMDEYHSFLFDGLVLGYLMAALDSGYSEQLNGKAWVISDKAIFETNRQRERIGIFLGFCSKYGLKSAFEFQTDQLFEQTNLNQVIVCLSQLGIEAQTKPN--YHGPKDYWMAKHQQNKREFTEEQLRSGESVIGLQMGTNKTANASGVS-FGAQRHI 742
R G +++VQ+K+ Q+D ++WI + + + + + + +L DG VL L+ +L Y E G+A V +A +Q E+I FL +YG+ + FQT L+E N+ V L LG A + + + G +++ K ++N R F++ QL+ G++VIGLQMGTN+ A+ +G++ +G R I
Sbjct: 4 RGPSYGLSREVQQKIEKQYDADLEQILIQWIT-------TQCREDVGQ-----PQPGRENFQKWLKDGTVLCKLINSL---YPE---GQAPVKKIQASSMAFKQMEQISQFLQAAERYGINTTDIFQTVDLWEGKNMACVQRTLMNLGGLAVARDDGLFSGDPNWFPKKSKENPRNFSDNQLQEGKNVIGLQMGTNRGASQAGMTGYGMPRQI 198
BLAST of Myophilin vs. UniProt/SwissProt
Match: sp|Q24799|MYPH_ECHGR (Myophilin OS=Echinococcus granulosus OX=6210 PE=2 SV=1) HSP 1 Score: 102.834 bits (255), Expect = 1.965e-25 Identity = 72/208 (34.62%), Postives = 103/208 (49.52%), Query Frame = 2
Query: 125 SGFAKDVQEKLAAQFDKSEAGKTLRWIKMLNATVPSHIKAAFDKIPTNIQECSMDEYHSFLFDGLVLGYLMAALDSGYSEQLNGKAWVISDKAIFETNRQRERIGIFLGFCSKYGLKSAFEFQTDQLFEQTNLNQVIVCLSQLGIEAQTKPNYHGPKDYWMAKHQQNKREFTEEQLRSGESVIGLQMGTNKTANASGVSFGAQRHITD 748
SG + V++KL + DK + + L WI+ L + +K K+ Y L DG VL LM ++ G +++N A + + E I FL YG+ A FQT LFE+ ++ QV L LG QT P Y GP +NKREFTE+QLR G++V+ LQ G+NK A+ +G++ G QR I D
Sbjct: 8 SGLSYQVKKKLEGKRDKDQENEALEWIEAL-----TGLKLDRSKL-----------YEDILKDGTVLCKLMNSIKPGCIKKINENATM--------PFKIMENISAFLEAMKGYGVPVADLFQTVDLFEKKDIAQVTRTLFALGRTCQTHPEYSGPV-LGPKLATENKREFTEQQLREGQNVVSLQYGSNKGASQAGINMGKQRMIMD 190
BLAST of Myophilin vs. UniProt/SwissProt
Match: sp|P19966|TAGL_CHICK (Transgelin OS=Gallus gallus OX=9031 GN=TAGLN PE=1 SV=3) HSP 1 Score: 97.8265 bits (242), Expect = 1.986e-23 Identity = 69/210 (32.86%), Postives = 106/210 (50.48%), Query Frame = 2
Query: 128 GFAKDVQEKLAAQFDKSEAGKTLRWI-KMLNATV--PSHIKAAFDKIPTNIQECSMDEYHSFLFDGLVLGYLMAALDSGYSEQLNGKAWVISDKAIFETNRQRERIGIFLGFCSKYGLKSAFEFQTDQLFEQTNLNQVIVCLSQLGIEAQTKPN--YHGPKDYWMAKHQQNKREFTEEQLRSGESVIGLQMGTNKTANASGVSFGAQRHI 742
G ++DVQ K+ ++D + + WI ++V P + F +L +G+VL L+ +L S+ + I D +Q E+I FL YG+ FQT LFE ++ V L LG A TK + YHG +++M K Q++KREF+E QL+ G+++IGLQMGTNK A+ +G+S+G R I
Sbjct: 9 GMSRDVQSKIEKKYDDELEDRLVEWIVAQCGSSVGRPDRGRLGF---------------QVWLKNGIVLSQLVNSLYPDGSKPVK-----IPDSPPTMVFKQMEQIAQFLKAAEDYGVVKTDMFQTVDLFEAKDMAAVQRTLVALGSLAVTKNDGHYHGDPNWFMKKAQEHKREFSESQLKEGKNIIGLQMGTNKGASQAGMSYGRPRQI 198
BLAST of Myophilin vs. UniProt/SwissProt
Match: sp|Q4R5J4|TAGL3_MACFA (Transgelin-3 OS=Macaca fascicularis OX=9541 GN=TAGLN3 PE=2 SV=1) HSP 1 Score: 92.8189 bits (229), Expect = 1.789e-21 Identity = 69/213 (32.39%), Postives = 104/213 (48.83%), Query Frame = 2
Query: 113 RAAKSGFAKDVQEKLAAQFDKSEAGKTLRWIKMLNATVPSHIKAAFDKIPTNIQECSMDEYHSFLFDGLVLGYLMAALDSGYSEQLNGKAWVISDKAIFETNRQRERIGIFLGFCSKYGLKSAFEFQTDQLFEQTNLNQVIVCLSQLGIEAQTKPN--YHGPKDYWMAKHQQNKREFTEEQLRSGESVIGLQMGTNKTANASGVS-FGAQRHI 742
R G +++VQEK+ ++D K + WI + A H + +L DG VL L+ +L E + + K F +Q E+I FL YG+++ FQT L+E ++ V L LG A TK + Y G ++ K QQN+R F+EEQLR G++VIGLQMG+NK A+ +G++ +G R I
Sbjct: 4 RGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPG------------RAHFQKWLMDGTVLCKLINSLYPPGQEPIPK---ISESKMAF---KQMEQISQFLKAAETYGVRTTDIFQTVDLWEGKDMAAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQMGSNKGASQAGMTGYGMPRQI 198
BLAST of Myophilin vs. UniProt/SwissProt
Match: sp|Q9UI15|TAGL3_HUMAN (Transgelin-3 OS=Homo sapiens OX=9606 GN=TAGLN3 PE=1 SV=2) HSP 1 Score: 92.8189 bits (229), Expect = 1.789e-21 Identity = 69/213 (32.39%), Postives = 104/213 (48.83%), Query Frame = 2
Query: 113 RAAKSGFAKDVQEKLAAQFDKSEAGKTLRWIKMLNATVPSHIKAAFDKIPTNIQECSMDEYHSFLFDGLVLGYLMAALDSGYSEQLNGKAWVISDKAIFETNRQRERIGIFLGFCSKYGLKSAFEFQTDQLFEQTNLNQVIVCLSQLGIEAQTKPN--YHGPKDYWMAKHQQNKREFTEEQLRSGESVIGLQMGTNKTANASGVS-FGAQRHI 742
R G +++VQEK+ ++D K + WI + A H + +L DG VL L+ +L E + + K F +Q E+I FL YG+++ FQT L+E ++ V L LG A TK + Y G ++ K QQN+R F+EEQLR G++VIGLQMG+NK A+ +G++ +G R I
Sbjct: 4 RGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPG------------RAHFQKWLMDGTVLCKLINSLYPPGQEPIPK---ISESKMAF---KQMEQISQFLKAAETYGVRTTDIFQTVDLWEGKDMAAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQMGSNKGASQAGMTGYGMPRQI 198
BLAST of Myophilin vs. UniProt/SwissProt
Match: sp|P37805|TAGL3_RAT (Transgelin-3 OS=Rattus norvegicus OX=10116 GN=Tagln3 PE=1 SV=2) HSP 1 Score: 92.4337 bits (228), Expect = 1.985e-21 Identity = 69/213 (32.39%), Postives = 104/213 (48.83%), Query Frame = 2
Query: 113 RAAKSGFAKDVQEKLAAQFDKSEAGKTLRWIKMLNATVPSHIKAAFDKIPTNIQECSMDEYHSFLFDGLVLGYLMAALDSGYSEQLNGKAWVISDKAIFETNRQRERIGIFLGFCSKYGLKSAFEFQTDQLFEQTNLNQVIVCLSQLGIEAQTKPN--YHGPKDYWMAKHQQNKREFTEEQLRSGESVIGLQMGTNKTANASGVS-FGAQRHI 742
R G +++VQEK+ ++D K + WI + A H + +L DG VL L+ +L E + + K F +Q E+I FL YG+++ FQT L+E ++ V L LG A TK + Y G ++ K QQN+R F+EEQLR G++VIGLQMG+NK A+ +G++ +G R I
Sbjct: 4 RGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPG------------RTHFQKWLMDGTVLCKLINSLYPPGQEPIPK---ISESKMAF---KQMEQISQFLKAAEVYGVRTTDIFQTVDLWEGKDMAAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQMGSNKGASQAGMTGYGMPRQI 198
BLAST of Myophilin vs. TrEMBL
Match: A0A5J4NL24 (Transgelin OS=Paragonimus westermani OX=34504 GN=DEA37_0014714 PE=4 SV=1) HSP 1 Score: 281.952 bits (720), Expect = 2.347e-92 Identity = 131/222 (59.01%), Postives = 167/222 (75.23%), Query Frame = 2
Query: 98 MAQNYRAAKSGFAKDVQEKLAAQFDKSEAGKTLRWIKMLNA--TVPSHIKAAFDKIPTNIQECSMDEYHSFLFDGLVLGYLMAALDSGYSEQLNG-KAWVISDKAIFETNRQRERIGIFLGFCSKYGLKSAFEFQTDQLFEQTNLNQVIVCLSQLGIEAQTKPNYHGPKDYWMAKHQQNKREFTEEQLRSGESVIGLQMGTNKTANASGVSFGAQRHITDSY 754
MA RA K+GFA+++Q+KL +FD +EA KTLRW +L A +P A +KIP +IQ M+ Y +L DGL LGYLMA LDS + +L K W ISDKA FET+RQR+RIG+FL F S+ G+ S F+FQTDQLFE TNL+QV+VCLSQ+G+EAQ KP + GP D+WM KH++NKREF+EEQLR+GE +IGLQMGT ANASGV+FG +RHITD++
Sbjct: 1 MASELRADKAGFAREMQQKLTEKFDGAEAAKTLRWFHVLRAPNNLPERFTKAVEKIPRDIQNVDMEAYAGYLRDGLALGYLMACLDSSIASRLESVKTWQISDKAPFETSRQRDRIGLFLRFASELGVASTFQFQTDQLFESTNLSQVVVCLSQVGVEAQAKPGFSGPTDFWMQKHRENKREFSEEQLRAGEGIIGLQMGTTAGANASGVTFGGRRHITDTF 222
BLAST of Myophilin vs. TrEMBL
Match: A0A4S2LX71 (Calponin-homology (CH) domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_004234 PE=4 SV=1) HSP 1 Score: 276.174 bits (705), Expect = 4.746e-90 Identity = 128/222 (57.66%), Postives = 171/222 (77.03%), Query Frame = 2
Query: 98 MAQNYRAAKSGFAKDVQEKLAAQFDKSEAGKTLRWIKMLNAT--VPSHIKAAFDKIPTNIQECSMDEYHSFLFDGLVLGYLMAALDSGYSEQLNG-KAWVISDKAIFETNRQRERIGIFLGFCSKYGLKSAFEFQTDQLFEQTNLNQVIVCLSQLGIEAQTKPNYHGPKDYWMAKHQQNKREFTEEQLRSGESVIGLQMGTNKTANASGVSFGAQRHITDSY 754
MA RA KSGFA++VQEKL +FD + A +TL+WI++L A VP++ A KIP +I+ M++Y +L DGLVLGYLMA L+ + QL K W ++D +FET+R+R+RIG FL F S+YG+ ++ +FQTDQL+E TNL QV +CLSQLG+EAQTKP++ GP+D+WM KHQ+++REFTEEQLRSG +VIGLQMGT ANASGVSFG++RHITD++
Sbjct: 2 MASGLRAEKSGFAREVQEKLKGKFDDALAARTLKWIRLLPAPAGVPNYFTDAVQKIPADIETVGMEDYAKYLNDGLVLGYLMACLNPKVTSQLGSVKTWQLADNPVFETSRRRDRIGQFLRFLSEYGVDASNQFQTDQLYESTNLVQVAICLSQLGVEAQTKPDFTGPRDFWMQKHQEHRREFTEEQLRSGSTVIGLQMGTTAGANASGVSFGSRRHITDTF 223
BLAST of Myophilin vs. TrEMBL
Match: A0A075A245 (Calponin-homology (CH) domain-containing protein OS=Opisthorchis viverrini OX=6198 GN=T265_01546 PE=4 SV=1) HSP 1 Score: 275.018 bits (702), Expect = 1.338e-89 Identity = 127/222 (57.21%), Postives = 169/222 (76.13%), Query Frame = 2
Query: 98 MAQNYRAAKSGFAKDVQEKLAAQFDKSEAGKTLRWIKMLNAT--VPSHIKAAFDKIPTNIQECSMDEYHSFLFDGLVLGYLMAALDSGYSEQLNG-KAWVISDKAIFETNRQRERIGIFLGFCSKYGLKSAFEFQTDQLFEQTNLNQVIVCLSQLGIEAQTKPNYHGPKDYWMAKHQQNKREFTEEQLRSGESVIGLQMGTNKTANASGVSFGAQRHITDSY 754
MA RA KSGFA++VQEKL +FD A +TL+WI++L A +P+H A KIP +I+ M++Y +L DGLVLGYLMA L+ + QL K W ++D +FET+R+R+RIG FL F S+YG+ ++ +FQTDQL+E TNL QV +CLSQLG+EAQTKP++ GP+D+WM KHQ+++REFTEEQLR+G +VIGLQMGT ANASGVSFG++RHITD +
Sbjct: 1 MASGLRAEKSGFAREVQEKLKGKFDNVLAARTLKWIRLLPAPAGIPNHFTDAVQKIPADIETVGMEDYAKYLNDGLVLGYLMACLNPKVTSQLGSVKTWQLADNPVFETSRRRDRIGQFLRFLSEYGVDASNQFQTDQLYESTNLVQVAICLSQLGVEAQTKPDFTGPRDFWMQKHQEHRREFTEEQLRAGSTVIGLQMGTTAGANASGVSFGSRRHITDMF 222
BLAST of Myophilin vs. TrEMBL
Match: H2KQ58 (Transgelin OS=Clonorchis sinensis OX=79923 GN=TAGLN PE=4 SV=1) HSP 1 Score: 273.863 bits (699), Expect = 3.276e-89 Identity = 127/222 (57.21%), Postives = 168/222 (75.68%), Query Frame = 2
Query: 98 MAQNYRAAKSGFAKDVQEKLAAQFDKSEAGKTLRWIKMLNAT--VPSHIKAAFDKIPTNIQECSMDEYHSFLFDGLVLGYLMAALDSGYSEQLNG-KAWVISDKAIFETNRQRERIGIFLGFCSKYGLKSAFEFQTDQLFEQTNLNQVIVCLSQLGIEAQTKPNYHGPKDYWMAKHQQNKREFTEEQLRSGESVIGLQMGTNKTANASGVSFGAQRHITDSY 754
MA RA KSGFA++VQEKL +FD A +TLRWI++L A +P++ A KIP NI+ M++Y +L DGL LGYLMA L+ + QL K W ++D +FET+R+R+RIG FL F S+YG+ ++ +FQTDQL+E TNL QV +CLSQLG+EAQTKP++ GP+D+WM KHQ+++REFTEEQLR+G +VIGLQMGT ANASGVSFG++RHITD +
Sbjct: 1 MASGLRAEKSGFAREVQEKLKGKFDDVLAARTLRWIRLLPAPTGIPNYFTEAVQKIPANIETVGMEDYAKYLNDGLALGYLMACLNPKVTSQLGSVKTWQLADNPVFETSRRRDRIGQFLRFLSEYGVDASNQFQTDQLYESTNLVQVAICLSQLGVEAQTKPDFTGPRDFWMQKHQEHRREFTEEQLRAGSTVIGLQMGTTAGANASGVSFGSRRHITDMF 222
BLAST of Myophilin vs. TrEMBL
Match: A0A564Y1S5 (Calponin-homology (CH) domain-containing protein OS=Hymenolepis diminuta OX=6216 GN=WMSIL1_LOCUS2246 PE=4 SV=1) HSP 1 Score: 271.552 bits (693), Expect = 2.497e-88 Identity = 127/222 (57.21%), Postives = 163/222 (73.42%), Query Frame = 2
Query: 98 MAQNYRAAKSGFAKDVQEKLAAQFDKSEAGKTLRWIKMLNA--TVPSHIKAAFDKIPTNIQECSMDEYHSFLFDGLVLGYLMAALDSGYSEQLNGKA-WVISDKAIFETNRQRERIGIFLGFCSKYGLKSAFEFQTDQLFEQTNLNQVIVCLSQLGIEAQTKPNYHGPKDYWMAKHQQNKREFTEEQLRSGESVIGLQMGTNKTANASGVSFGAQRHITDSY 754
MA YRA KSGFA++VQ ++ ++D EA K LRWI++L ++P + A +KIP +I S D+++ +L DGLVLGYL+ L + GKA W ISDKAIFETNRQRERIG F+ FC K G+ SA FQTDQL EQTNL QV++CLSQLG+EAQ KP+Y GP+ YWM +HQ+N+R FT+EQL++GESVIGLQMG AN SG++FGAQR +TD +
Sbjct: 1 MASGYRADKSGFAREVQARIMEKYDAEEAAKALRWIRLLKPANSLPESLTTAVEKIPQDISTVSADDFYKYLKDGLVLGYLIGCLRPDEVSKSLGKAMWTISDKAIFETNRQRERIGAFIDFCQKMGVASASAFQTDQLHEQTNLPQVVICLSQLGVEAQAKPDYTGPQGYWMQRHQENRRTFTKEQLKAGESVIGLQMGYTGGANQSGITFGAQRKVTDMF 222
BLAST of Myophilin vs. Ensembl Cavefish
Match: tagln3a (transgelin-3-like [Source:NCBI gene;Acc:103024278]) HSP 1 Score: 100.138 bits (248), Expect = 4.990e-25 Identity = 73/216 (33.80%), Postives = 109/216 (50.46%), Query Frame = 2
Query: 113 RAAKSGFAKDVQEKLAAQFDKSEAGKTLRWIKMLNATVPSHIKAAFDKIPTNIQECSMDEYHSFLFDGLVLGYLMAALDSGYSEQLNGKAWVISDKAIFETN---RQRERIGIFLGFCSKYGLKSAFEFQTDQLFEQTNLNQVIVCLSQLGIEAQTKPN--YHGPKDYWMAKHQQNKREFTEEQLRSGESVIGLQMGTNKTANASG-VSFGAQRHI 742
R G +++VQEK+ ++D + + WI ++ D + E + ++L DG +L L+ +L SE + K I ET +Q E+I FL YG+ FQT L+E +L V L LG EA TK + YHG KD++ K + ++REF+EEQLR G ++IGLQMG+N+ A+ SG V +G R I
Sbjct: 4 RGPSYGLSREVQEKIEQKYDPDLESRLVDWI---------MLQCGDDLVRP---EPGKQNFQTWLMDGTILCRLINSLYPSGSEPI---------KKIPETKMAFKQMEKISQFLEAAEVYGVVRGDIFQTVDLWEGKDLAAVQRTLMALGSEALTKDDGHYHGNKDWFRRKAKGHRREFSEEQLRQGRALIGLQMGSNRGASQSGMVGYGTPRQI 198
BLAST of Myophilin vs. Ensembl Cavefish
Match: TAGLN3 (transgelin 3 [Source:NCBI gene;Acc:103030448]) HSP 1 Score: 83.1889 bits (204), Expect = 6.078e-19 Identity = 65/216 (30.09%), Postives = 106/216 (49.07%), Query Frame = 2
Query: 113 RAAKSGFAKDVQEKLAAQFDKSEAGKTLRWIKMLNATVPSHIKAAFDKIPTNIQECSMDEYHSFLFDGLVLGYLMAALDSGYSEQLNGKAWVISDKAIFETN---RQRERIGIFLGFCSKYGLKSAFEFQTDQLFEQTNLNQVIVCLSQLGIEAQTKPN--YHGPKDYWMAKHQQNKREFTEEQLRSGESVIGLQMGTNKTANASGVS-FGAQRHI 742
R G +++V EK+ ++D + + WI A +++ + ++L DG +L L+ +L E + K I ET +Q E+I FL YG+ + FQT L+E ++ V L LG A TK + Y G +D++ Q N+REF+EEQLR G+++IGLQMG+N+ A+ +G++ +G R I
Sbjct: 4 RGPSYGLSREVLEKIEQKYDTDLEVRLVDWII---AQCGGNLERPLP---------GKQNFQNWLMDGTILCRLINSLYPRGKEPI---------KKIQETQMAFKQMEKISQFLVAAEAYGVITTDIFQTVDLWEGKDMAAVQRTLMALGSVALTKDDGHYRGNRDWFHRTAQSNRREFSEEQLRQGQNLIGLQMGSNRGASQAGMTGYGMHRQI 198
BLAST of Myophilin vs. Ensembl Cavefish
Match: tagln (transgelin-like [Source:NCBI gene;Acc:103045968]) HSP 1 Score: 83.1889 bits (204), Expect = 8.014e-19 Identity = 65/220 (29.55%), Postives = 104/220 (47.27%), Query Frame = 2
Query: 128 GFAKDVQEKLAAQFDKSEAGKTLRWIKML---NATVPSHIKAAFDKIPTNIQECSMDEYHSFLFDGLVLGYLMAALDSGYSEQLNGKAWVISDKAIFETN------RQRERIGIFLGFCSKYGLKSAFEFQTDQLFEQTNLNQVIVCLSQLGIEAQTKPNYH--GPKDYWMAKHQQNKREFTEEQLRSGESVIGLQMGTNKTANASGVS-FGAQRHITDS 751
G ++ VQ+K+ ++D + + WI P+ K F +L DG VL L+ +L SDK + + +Q E++ FL YG+ FQT L+E +L V L LG A TK + H G D++ K Q+N+R+F+++QL+SG+ VIGLQMG+NK A+ +G++ +G R I ++
Sbjct: 17 GLSRQVQDKIDRKYDPELEARLVEWIVAQCGSGVAKPAEGKQGF---------------QDWLKDGCVLSELINSLHD-------------SDKPVKKIQSSPMAFKQMEQVSQFLNAAEAYGVTKTDMFQTVDLWEGKDLAAVQRTLMALGSIAVTKDDGHFRGNPDWFFKKAQENRRDFSDDQLKSGKHVIGLQMGSNKGASQAGMTGYGRPRQIMNN 208
BLAST of Myophilin vs. Ensembl Cavefish
Match: cnn1b (calponin 1 [Source:NCBI gene;Acc:103040806]) HSP 1 Score: 81.2629 bits (199), Expect = 1.627e-17 Identity = 65/219 (29.68%), Postives = 103/219 (47.03%), Query Frame = 2
Query: 104 QNYRAAKS-GFAKDVQEKLAAQFDKSEAGKTLRWIKMLNATVPSHIKAAFDKIPTNIQECSMDEYHSFLFDGLVLGYLMAALDSGYSEQLNGKA--WVISDKAIFETNRQRERIGIFLGFCSKYGLKSAFEFQTDQLFEQTNLNQVIVCLSQLGIEAQTKPNYHGPKDYWMAKHQQNKREFTEEQLRSGESVIGLQMGTNKTANASGV-SFGAQRHITD 748
Q++R+ + G + +V+ KLA ++D + + WI + K+P N E L DG+ L L+ AL G ++N + W Q E IG F+ +YGL+ F+ + LFE N QV L L A++K D + ++ +R F E+L+ G ++IGLQMGTNK A+ G+ S+G +RH+ D
Sbjct: 4 QHFRSGPAFGLSAEVKSKLAQKYDPQKEEELRLWINEVTGR----------KVPDNFMEG--------LKDGVTLCELINALQPGTVRKINNSSQNW-----------HQLENIGNFVRGIQEYGLRPHDIFEANDLFENVNHTQVQSTLIALAGMAKSK-GLRTKYDIGVKYAEKQQRRFAPEKLKEGRNIIGLQMGTNKFASQKGMTSYGTRRHLYD 192
BLAST of Myophilin vs. Ensembl Cavefish
Match: tagln (transgelin-like [Source:NCBI gene;Acc:103045968]) HSP 1 Score: 76.6406 bits (187), Expect = 1.510e-16 Identity = 45/114 (39.47%), Postives = 70/114 (61.40%), Query Frame = 2
Query: 419 RQRERIGIFLGFCSKYGLKSAFEFQTDQLFEQTNLNQVIVCLSQLGIEAQTKPNYH--GPKDYWMAKHQQNKREFTEEQLRSGESVIGLQMGTNKTANASGVS-FGAQRHITDS 751
+Q E++ FL YG+ FQT L+E +L V L LG A TK + H G D++ K Q+N+R+F+++QL+SG+ VIGLQMG+NK A+ +G++ +G R I ++
Sbjct: 75 KQMEQVSQFLNAAEAYGVTKTDMFQTVDLWEGKDLAAVQRTLMALGSIAVTKDDGHFRGNPDWFFKKAQENRRDFSDDQLKSGKHVIGLQMGSNKGASQAGMTGYGRPRQIMNN 188
BLAST of Myophilin vs. Ensembl Nematostella
Match: EDO30654 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T056]) HSP 1 Score: 84.3445 bits (207), Expect = 1.326e-20 Identity = 48/108 (44.44%), Postives = 65/108 (60.19%), Query Frame = 2
Query: 428 ERIGIFLGFCSKYGLKSAFEFQTDQLFEQTNLNQVIVCLSQLGIEAQTKP---NYHGPKDYWMAKHQQNKREFTEEQLRSGESVIGLQMGTNKTANASGVSFGAQRHI 742
E I FL FC +G+ + FQT L+E+ N+ QVI + L +A +K GPK+ Q+N REFTEEQ R+GE VIGLQMG+NK A+ +G +FG R +
Sbjct: 7 ENIAKFLDFCGTFGVAKSDLFQTVDLYEKQNIQQVINSIYALARKANSKGLSVPILGPKE-----SQKNPREFTEEQKRAGEGVIGLQMGSNKGASQAGDTFGRPRQV 109
BLAST of Myophilin vs. Ensembl Nematostella
Match: EDO30656 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T059]) HSP 1 Score: 84.7297 bits (208), Expect = 4.032e-20 Identity = 48/108 (44.44%), Postives = 65/108 (60.19%), Query Frame = 2
Query: 428 ERIGIFLGFCSKYGLKSAFEFQTDQLFEQTNLNQVIVCLSQLGIEAQTKP---NYHGPKDYWMAKHQQNKREFTEEQLRSGESVIGLQMGTNKTANASGVSFGAQRHI 742
E I FL FC +G+ + FQT L+E+ N+ QVI + L +A +K GPK+ Q+N REFTEEQ R+GE VIGLQMG+NK A+ +G +FG R +
Sbjct: 67 ENIAKFLDFCGTFGVAKSDLFQTVDLYEKQNIQQVINSIHALARKANSKGLSVPILGPKE-----SQKNPREFTEEQKRAGEGVIGLQMGSNKGASQAGDTFGRPRQV 169
BLAST of Myophilin vs. Ensembl Nematostella
Match: EDO46712 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RPC0]) HSP 1 Score: 84.3445 bits (207), Expect = 7.843e-20 Identity = 69/217 (31.80%), Postives = 96/217 (44.24%), Query Frame = 2
Query: 113 RAAKSGFAKDVQEKLAAQFDKSEAGKTLRWIK-MLNATVPSHIKAAFDKIPTNIQECSMDEYHSFLFDGLVLGYLMAALDSGYSEQLNGKAWVISDKAIFETNRQRERIGIFLGFCSKYGLKSAFEFQTDQLFEQTNLNQVIVCLSQLGIEAQTKPNYH---GPKDYWMAKHQQNKREFTEEQLRSGESVIGLQMGTNKTANASGVSFGAQRHITDS 751
R G ++ K A++D A + WI+ +L V A D+ H L DG VL + + +L G + S K F + E G FL FC G+ FQT L+E+ N+ VI + LG +A + GPK+ N REFTEEQ R+G+ VIGLQMG+NK A+ +G FG R + S
Sbjct: 4 RPKGYGMTAELARKRDAKYDSDLAAQATAWIEGILGERVFGGKTGA-------------DDVHEVLKDGQVLCRV--------ANKLGGNIKINSSKMAF---KMMENTGKFLEFCDTIGVPKTDMFQTVDLYEKQNMPGVINGIHALGRKAHSTGKTCLALGPKEA-----SANPREFTEEQRRAGQGVIGLQMGSNKGASQAGDHFGRPRQVAGS 191
BLAST of Myophilin vs. Ensembl Nematostella
Match: EDO44075 (Myophilin-like protein; Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RWR1]) HSP 1 Score: 82.8037 bits (203), Expect = 3.273e-19 Identity = 56/162 (34.57%), Postives = 80/162 (49.38%), Query Frame = 2
Query: 287 DEYHSFLFDGLVLGYLMAALDSGYSEQLNGKAWVISDKAIFETNRQRERIGIFLGFCSKYGLKSAFEFQTDQLFEQTNLNQVIVCLSQLGIEAQTKPNYH----GPKDYWMAKHQQNKREFTEEQLRSGESVIGLQMGT--NKTANASGVSFGAQRHITDSY 754
D+ L DG +L L +L K V F +Q E IG FL C G+ S +FQT L++ N+ VI C+ +G + Q + GPK+ + N REFTEEQLR+GES++G+Q G ++ A+ SG +G R ITD +
Sbjct: 50 DDVQKVLKDGKILARLAI--------KLGAKIKVNEQNMPF---KQMENIGNFLSHCGHLGVASGDQFQTADLYDNANMTSVISCIHAVGRKCQLIKDLDIPTLGPKEA-----EANVREFTEEQLRAGESILGMQAGPTQDQVASQSGDHYGRGRQITDQH 195
BLAST of Myophilin vs. Ensembl Nematostella
Match: EDO30655 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T057]) HSP 1 Score: 58.9214 bits (141), Expect = 7.074e-12 Identity = 29/52 (55.77%), Postives = 37/52 (71.15%), Query Frame = 2
Query: 587 GPKDYWMAKHQQNKREFTEEQLRSGESVIGLQMGTNKTANASGVSFGAQRHI 742
GPK+ Q+N REFTEEQ R+GE VIGLQMG+NK A+ +G +FG R +
Sbjct: 8 GPKE-----SQKNPREFTEEQKRAGEGVIGLQMGSNKGASQAGDTFGRPRQV 54
BLAST of Myophilin vs. Ensembl Medaka
Match: tagln (transgelin [Source:NCBI gene;Acc:101169057]) HSP 1 Score: 94.7449 bits (234), Expect = 4.191e-23 Identity = 72/227 (31.72%), Postives = 115/227 (50.66%), Query Frame = 2
Query: 77 LSSNSLTMAQNYRAAKSGFAKDVQEKLAAQFDKSEAGKTLRWI-KMLNATV--PSHIKAAFDKIPTNIQECSMDEYHSFLFDGLVLGYLMAALDSGYSEQLNGKAWVISDKAIFETNRQRERIGIFLGFCSKYGLKSAFEFQTDQLFEQTNLNQVIVCLSQLGIEAQTKP--NYHGPKDYWMAKHQQNKREFTEEQLRSGESVIGLQMGTNKTANASGVSFGAQRHI 742
+++ S MA + G ++ VQEK+ +++D + WI + + V P K F ++L DG +LG L+ +L G+ V ++ +Q E+I FL KYG+ FQT L+E +L V LS LG A TK Y+G +++ K Q+NKR+F+++QL++G++VIGLQMG+NK A+ G+S+G R I
Sbjct: 1 MATKSAGMAN--KGPSYGMSRQVQEKIDSKYDPELEQILVEWICRQCGSGVGRPEPGKMGF---------------QAWLKDGCILGELINSL-------FAGEKPVKKTQSSPMAFKQMEQISQFLNAAEKYGVTKTDMFQTVDLWEGKDLAAVQRTLSALGSLAVTKDEGTYNGDPNWFFKKAQENKRDFSDDQLKAGKNVIGLQMGSNKGASQEGMSYGRPRQI 203
BLAST of Myophilin vs. Ensembl Medaka
Match: tagln (transgelin [Source:NCBI gene;Acc:101169057]) HSP 1 Score: 94.3597 bits (233), Expect = 4.980e-23 Identity = 69/210 (32.86%), Postives = 108/210 (51.43%), Query Frame = 2
Query: 128 GFAKDVQEKLAAQFDKSEAGKTLRWI-KMLNATV--PSHIKAAFDKIPTNIQECSMDEYHSFLFDGLVLGYLMAALDSGYSEQLNGKAWVISDKAIFETNRQRERIGIFLGFCSKYGLKSAFEFQTDQLFEQTNLNQVIVCLSQLGIEAQTKP--NYHGPKDYWMAKHQQNKREFTEEQLRSGESVIGLQMGTNKTANASGVSFGAQRHI 742
G ++ VQEK+ +++D + WI + + V P K F ++L DG +LG L+ +L G+ V ++ +Q E+I FL KYG+ FQT L+E +L V LS LG A TK Y+G +++ K Q+NKR+F+++QL++G++VIGLQMG+NK A+ G+S+G R I
Sbjct: 9 GMSRQVQEKIDSKYDPELEQILVEWICRQCGSGVGRPEPGKMGF---------------QAWLKDGCILGELINSL-------FAGEKPVKKTQSSPMAFKQMEQISQFLNAAEKYGVTKTDMFQTVDLWEGKDLAAVQRTLSALGSLAVTKDEGTYNGDPNWFFKKAQENKRDFSDDQLKAGKNVIGLQMGSNKGASQEGMSYGRPRQI 196
BLAST of Myophilin vs. Ensembl Medaka
Match: ENSORLT00000028673.1 (transgelin [Source:NCBI gene;Acc:101159525]) HSP 1 Score: 91.6633 bits (226), Expect = 5.379e-22 Identity = 74/219 (33.79%), Postives = 108/219 (49.32%), Query Frame = 2
Query: 113 RAAKSGFAKDVQEKLAAQFDKSEAGKTLRWI-KMLNATV--PSHIKAAFDKIPTNIQECSMDEYHSFLFDGLVLGYLMAALDSGYSEQLNGKAWVISDKAIFETNRQRERIGIFLGFCSKYGLKSAFEFQTDQLFEQTNLNQVIVCLSQLGIEAQTK--PNYHGPKDYWMAKHQQNKREFTEEQLRSGESVIGLQMGTNKTANASGVS-FGAQRHITDS 751
R G +++VQ K+ ++D + ++WI + V P K F K +L DG VL L+ +L Y K S A +Q E+I +FL + YG+ FQT LFE +L V L LG A TK NY G +++ K Q+N+R+F+EEQL G+SVIGLQMGTNK A+ +G++ +G R I ++
Sbjct: 4 RGPAYGLSREVQSKIDKKYDPELEERLVQWIIAQCGSGVGQPEPDKTGFQK---------------WLKDGCVLCELINSL---YGANKPIKTIKNSTMAF----KQMEQISLFLKYAEAYGVIKTDMFQTVDLFESKDLAAVQRTLMALGSLAVTKNDGNYRGDPNWFHRKAQENRRDFSEEQLSGGKSVIGLQMGTNKGASQAGMTGYGRPRQIINN 200
BLAST of Myophilin vs. Ensembl Medaka
Match: tagln3a (transgelin 3 [Source:NCBI gene;Acc:101158980]) HSP 1 Score: 91.6633 bits (226), Expect = 6.426e-22 Identity = 70/216 (32.41%), Postives = 107/216 (49.54%), Query Frame = 2
Query: 113 RAAKSGFAKDVQEKLAAQFDKSEAGKTLRWIKMLNATVPSHIKAAFDKIPTNIQECSMDEYHSFLFDGLVLGYLMAALDSGYSEQLNGKAWVISDKAIFETN---RQRERIGIFLGFCSKYGLKSAFEFQTDQLFEQTNLNQVIVCLSQLGIEAQTKPN--YHGPKDYWMAKHQQNKREFTEEQLRSGESVIGLQMGTNKTANASGVS-FGAQRHI 742
R G +++VQEK+ ++D + + WI S +K + + + +L DG +L L+ +L E + K I ET +Q E+I FL YG+ + FQT L+E ++ V L LG A TK + Y G +D++ K Q +REFTEEQLR G+S+IGLQMG+N+ A+ SG++ +G R I
Sbjct: 17 RGPSYGLSREVQEKIEQKYDPDLEQRLVDWIV-------SQCGGNLEK-----PQPGKENFQKWLMDGTILCRLINSLFPRGKEPI---------KKIPETQMAFKQMEKISQFLQAAEAYGVTTTDIFQTVDLWEGKDMAAVQRTLMALGSLAVTKDDGHYKGDRDWFHRKAQGYRREFTEEQLRQGQSLIGLQMGSNRGASQSGMTGYGMHRQI 211
BLAST of Myophilin vs. Ensembl Medaka
Match: tagln3a (transgelin 3 [Source:NCBI gene;Acc:101158980]) HSP 1 Score: 91.2781 bits (225), Expect = 9.081e-22 Identity = 70/216 (32.41%), Postives = 107/216 (49.54%), Query Frame = 2
Query: 113 RAAKSGFAKDVQEKLAAQFDKSEAGKTLRWIKMLNATVPSHIKAAFDKIPTNIQECSMDEYHSFLFDGLVLGYLMAALDSGYSEQLNGKAWVISDKAIFETN---RQRERIGIFLGFCSKYGLKSAFEFQTDQLFEQTNLNQVIVCLSQLGIEAQTKPN--YHGPKDYWMAKHQQNKREFTEEQLRSGESVIGLQMGTNKTANASGVS-FGAQRHI 742
R G +++VQEK+ ++D + + WI S +K + + + +L DG +L L+ +L E + K I ET +Q E+I FL YG+ + FQT L+E ++ V L LG A TK + Y G +D++ K Q +REFTEEQLR G+S+IGLQMG+N+ A+ SG++ +G R I
Sbjct: 26 RGPSYGLSREVQEKIEQKYDPDLEQRLVDWIV-------SQCGGNLEK-----PQPGKENFQKWLMDGTILCRLINSLFPRGKEPI---------KKIPETQMAFKQMEKISQFLQAAEAYGVTTTDIFQTVDLWEGKDMAAVQRTLMALGSLAVTKDDGHYKGDRDWFHRKAQGYRREFTEEQLRQGQSLIGLQMGSNRGASQSGMTGYGMHRQI 220
BLAST of Myophilin vs. Planmine SMEST
Match: SMESG000035348.1 (SMESG000035348.1) HSP 1 Score: 461.84 bits (1187), Expect = 4.918e-167 Identity = 219/219 (100.00%), Postives = 219/219 (100.00%), Query Frame = 2
Query: 98 MAQNYRAAKSGFAKDVQEKLAAQFDKSEAGKTLRWIKMLNATVPSHIKAAFDKIPTNIQECSMDEYHSFLFDGLVLGYLMAALDSGYSEQLNGKAWVISDKAIFETNRQRERIGIFLGFCSKYGLKSAFEFQTDQLFEQTNLNQVIVCLSQLGIEAQTKPNYHGPKDYWMAKHQQNKREFTEEQLRSGESVIGLQMGTNKTANASGVSFGAQRHITDSY 754
MAQNYRAAKSGFAKDVQEKLAAQFDKSEAGKTLRWIKMLNATVPSHIKAAFDKIPTNIQECSMDEYHSFLFDGLVLGYLMAALDSGYSEQLNGKAWVISDKAIFETNRQRERIGIFLGFCSKYGLKSAFEFQTDQLFEQTNLNQVIVCLSQLGIEAQTKPNYHGPKDYWMAKHQQNKREFTEEQLRSGESVIGLQMGTNKTANASGVSFGAQRHITDSY
Sbjct: 1 MAQNYRAAKSGFAKDVQEKLAAQFDKSEAGKTLRWIKMLNATVPSHIKAAFDKIPTNIQECSMDEYHSFLFDGLVLGYLMAALDSGYSEQLNGKAWVISDKAIFETNRQRERIGIFLGFCSKYGLKSAFEFQTDQLFEQTNLNQVIVCLSQLGIEAQTKPNYHGPKDYWMAKHQQNKREFTEEQLRSGESVIGLQMGTNKTANASGVSFGAQRHITDSY 219
BLAST of Myophilin vs. Planmine SMEST
Match: SMESG000049198.1 (SMESG000049198.1) HSP 1 Score: 166.007 bits (419), Expect = 6.896e-51 Identity = 77/100 (77.00%), Postives = 84/100 (84.00%), Query Frame = 2
Query: 122 KSGFAKDVQEKLAAQFDKSEAGKTLRWIKMLNATVPSHIKAAFDKIPTNIQECSMDEYHSFLFDGLVLGYLMAALDSGYSEQLNGKAWVISDKAIFETNR 421
++G D+ A QFDKSE GKTLRWI+MLNATVPSHIKAAFDKIPTNIQECSMDEYH+FLFDGLVLGYLMAAL SG+SEQLNGKAWV SD I N+
Sbjct: 79 QAGITSDIIPPQAVQFDKSETGKTLRWIEMLNATVPSHIKAAFDKIPTNIQECSMDEYHNFLFDGLVLGYLMAALGSGHSEQLNGKAWVNSDANILVLNQ 178
BLAST of Myophilin vs. Planmine SMEST
Match: SMESG000021223.1 (SMESG000021223.1) HSP 1 Score: 159.073 bits (401), Expect = 3.449e-48 Identity = 77/106 (72.64%), Postives = 83/106 (78.30%), Query Frame = 2
Query: 128 GFAKDVQEKLAAQFDKSEAGKTLRWIKMLNATVPSHIKAAFDKIPTNIQECSMDEYHSFLFDGLVLGYLMAALDSGYSEQLNGKAWVISDKAIFETNRQRERIGIF 445
G + AAQFDKSEAGKTLRWI+MLNATVPS IKAA DKIPTNIQECSMDEYH+FLFDGLVLGYLMAAL SG+SEQLNG WV SD +I N Q IG+
Sbjct: 48 GITSHIISPQAAQFDKSEAGKTLRWIEMLNATVPSRIKAALDKIPTNIQECSMDEYHNFLFDGLVLGYLMAALGSGHSEQLNGNNWVNSDASILILN-QNLSIGVL 152
BLAST of Myophilin vs. Planmine SMEST
Match: SMESG000033260.1 (SMESG000033260.1) HSP 1 Score: 157.918 bits (398), Expect = 8.539e-48 Identity = 78/130 (60.00%), Postives = 93/130 (71.54%), Query Frame = 2
Query: 38 LFKWSINMNLIQILSSNSLTMAQNYRAAKS--GFAKDVQEKLAAQFDKSEAGKTLRWIKMLNATVPSHIKAAFDKIPTNIQECSMDEYHSFLFDGLVLGYLMAALDSGYSEQLNGKAWVISDKAIFETNR 421
L+++ ++ + L+ + T + K G + AAQFDKSEAGKTLRWI+MLNATVPS IKAA DKIPTNIQECSMDEYH+FLFDGLVLGYLM AL SG+SEQLNGK WV SD +I N+
Sbjct: 26 LYQYDVSCRSVNRLTKEATTAREVLSTLKPQVGITSHIISCQAAQFDKSEAGKTLRWIEMLNATVPSRIKAALDKIPTNIQECSMDEYHNFLFDGLVLGYLMTALGSGHSEQLNGKTWVNSDASILILNQ 155
BLAST of Myophilin vs. Planmine SMEST
Match: SMESG000047694.1 (SMESG000047694.1) HSP 1 Score: 155.992 bits (393), Expect = 1.563e-47 Identity = 77/100 (77.00%), Postives = 84/100 (84.00%), Query Frame = 2
Query: 122 KSGFAKDVQEKLAAQFDKSEAGKTLRWIKMLNATVPSHIKAAFDKIPTNIQECSMDEYHSFLFDGLVLGYLMAALDSGYSEQLNGKAWVISDKAIFETNR 421
++G D+ + AAQFDK EAGKTLRWI+MLNATVPSHIKAA DKIPTNIQECSMDEYHSFLF GLVLGYLMAAL SGYSEQLN KAWV SD +I N+
Sbjct: 24 QAGITSDIIPQ-AAQFDKIEAGKTLRWIEMLNATVPSHIKAALDKIPTNIQECSMDEYHSFLF-GLVLGYLMAALGSGYSEQLNRKAWVNSDASILVFNQ 121 The following BLAST results are available for this feature:
BLAST of Myophilin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Myophilin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Myophilin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Myophilin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Myophilin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Myophilin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Myophilin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Myophilin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Myophilin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Myophilin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 0
BLAST of Myophilin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Myophilin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Myophilin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Myophilin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30020269 ID=SMED30020269|Name=Myophilin|organism=Schmidtea mediterranea sexual|type=transcript|length=841bpback to top protein sequence of SMED30020269-orf-1 >SMED30020269-orf-1 ID=SMED30020269-orf-1|Name=SMED30020269-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=233bp MNLIQILSSNSLTMAQNYRAAKSGFAKDVQEKLAAQFDKSEAGKTLRWIKback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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