Dynamin-type G domain-containing protein
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30020268 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 36Note: Hover over icons to view figure legend
Homology
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Human
Match: MFN2 (mitofusin 2 [Source:HGNC Symbol;Acc:HGNC:16877]) HSP 1 Score: 117.472 bits (293), Expect = 4.586e-26 Identity = 75/242 (30.99%), Postives = 127/242 (52.48%), Query Frame = 2 Query: 1817 TKVRFIEGKVKKDSIKISFFGTVSAGKSKVLNTIIGENLFLSAVADTTSCFVAVRKSDRGRHYLRVEGSETNFDSLTNLKNKVKELTTHLSENTTGRLDTTKTVQVFLNIENEIMKNNTEIFDCPGSNNKREVTECIMQQSLDSDIFIFVMTC--TLTNEEKDFFEYQSKLSSKPDIFVLVNKWDKSDQDKTAVTEKSRIKIKREIVNLLTKDGNFSSEEASKRIFFVSALEMFKCRIERKE 2536 +KVR I + + +K++FFG S GKS V+N ++ + + S + TT+CF+ V +D +L EGSE + T V +L L ++ + +V ++ N + ++K++ + D PG + E+ I + LD+D+F+ V TL EK FF S+ S+P+IF+L N+WD S + + E R ++R L+ + G +A RIFFVSA E+ RI++ + Sbjct: 83 SKVRGISEVLARRHMKVAFFGRTSNGKSTVINAMLWDKVLPSGIGHTTNCFLRVEGTDGHEAFLLTEGSEEKRSAKT-----VNQLAHALHQDKQLHAGSLVSV-MWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKHFFHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHMERCTSFLVDELGVVDRSQAGDRIFFVSAKEVLNARIQKAQ 318 HSP 2 Score: 109.768 bits (273), Expect = 1.478e-23 Identity = 69/241 (28.63%), Postives = 123/241 (51.04%), Query Frame = 2 Query: 230 KINNIREILNKSEINVIFVGGVSTGKSKIINSILEEEILPSSIGVTNTKVVRLTGSNNGTSCIKGCDKEFKDKEAMYEEVMNVSTDELDGNDNEALIEVVISNPKKPILNDKTFLIDTPGYNGNERAKELVMRTCQVSDIIVFVMT--YVFSDEEKEMFKLISEKTSKLNLFILVNKWDESDSDETFTVKMSKDMIEGRFVDWFKD-YNDTERNTAKSRIFFISAKEQMDSFMEAKEGINE 943 K+ I E+L + + V F G S GKS +IN++L +++LPS IG T +R+ G++ + + E K ++ + + + +L+ V+ N K P+L D L+D+PG + + + C +D+ V V EK F +SE+ S+ N+FIL N+WD S S+ + ++ + +E R + D +R+ A RIFF+SAKE +++ ++ +G+ E Sbjct: 84 KVRGISEVLARRHMKVAFFGRTSNGKSTVINAMLWDKVLPSGIGHTTNCFLRVEGTDGHEAFLLTEGSEEKRSAKTVNQLAHALHQDKQLHAG-SLVSVMWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKHFFHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHME-RCTSFLVDELGVVDRSQAGDRIFFVSAKEVLNARIQKAQGMPE 322
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Human
Match: MFN2 (mitofusin 2 [Source:HGNC Symbol;Acc:HGNC:16877]) HSP 1 Score: 117.472 bits (293), Expect = 4.586e-26 Identity = 75/242 (30.99%), Postives = 127/242 (52.48%), Query Frame = 2 Query: 1817 TKVRFIEGKVKKDSIKISFFGTVSAGKSKVLNTIIGENLFLSAVADTTSCFVAVRKSDRGRHYLRVEGSETNFDSLTNLKNKVKELTTHLSENTTGRLDTTKTVQVFLNIENEIMKNNTEIFDCPGSNNKREVTECIMQQSLDSDIFIFVMTC--TLTNEEKDFFEYQSKLSSKPDIFVLVNKWDKSDQDKTAVTEKSRIKIKREIVNLLTKDGNFSSEEASKRIFFVSALEMFKCRIERKE 2536 +KVR I + + +K++FFG S GKS V+N ++ + + S + TT+CF+ V +D +L EGSE + T V +L L ++ + +V ++ N + ++K++ + D PG + E+ I + LD+D+F+ V TL EK FF S+ S+P+IF+L N+WD S + + E R ++R L+ + G +A RIFFVSA E+ RI++ + Sbjct: 83 SKVRGISEVLARRHMKVAFFGRTSNGKSTVINAMLWDKVLPSGIGHTTNCFLRVEGTDGHEAFLLTEGSEEKRSAKT-----VNQLAHALHQDKQLHAGSLVSV-MWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKHFFHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHMERCTSFLVDELGVVDRSQAGDRIFFVSAKEVLNARIQKAQ 318 HSP 2 Score: 109.768 bits (273), Expect = 1.478e-23 Identity = 69/241 (28.63%), Postives = 123/241 (51.04%), Query Frame = 2 Query: 230 KINNIREILNKSEINVIFVGGVSTGKSKIINSILEEEILPSSIGVTNTKVVRLTGSNNGTSCIKGCDKEFKDKEAMYEEVMNVSTDELDGNDNEALIEVVISNPKKPILNDKTFLIDTPGYNGNERAKELVMRTCQVSDIIVFVMT--YVFSDEEKEMFKLISEKTSKLNLFILVNKWDESDSDETFTVKMSKDMIEGRFVDWFKD-YNDTERNTAKSRIFFISAKEQMDSFMEAKEGINE 943 K+ I E+L + + V F G S GKS +IN++L +++LPS IG T +R+ G++ + + E K ++ + + + +L+ V+ N K P+L D L+D+PG + + + C +D+ V V EK F +SE+ S+ N+FIL N+WD S S+ + ++ + +E R + D +R+ A RIFF+SAKE +++ ++ +G+ E Sbjct: 84 KVRGISEVLARRHMKVAFFGRTSNGKSTVINAMLWDKVLPSGIGHTTNCFLRVEGTDGHEAFLLTEGSEEKRSAKTVNQLAHALHQDKQLHAG-SLVSVMWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKHFFHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHME-RCTSFLVDELGVVDRSQAGDRIFFVSAKEVLNARIQKAQGMPE 322
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Human
Match: MFN1 (mitofusin 1 [Source:HGNC Symbol;Acc:HGNC:18262]) HSP 1 Score: 106.686 bits (265), Expect = 7.066e-24 Identity = 71/242 (29.34%), Postives = 129/242 (53.31%), Query Frame = 2 Query: 1820 KVRFIEGKVKKDSIKISFFGTVSAGKSKVLNTIIGENLFLSAVADTTSCFVAVRKSDRGRHYLRVEGSETNFDSLTNLKNKVKELTTHLSENTTGRLDTTKTVQVFL-NIENEIMKNNTEIFDCPGSNNKREVTECIMQQSLDSDIFIFVMTC--TLTNEEKDFFEYQSKLSSKPDIFVLVNKWDKSDQDKTAVTEKSRIKIKREIVNLLTKDGNFSSEEASKRIFFVSALEMFKCRIERKE 2536 K+ I + + +K++FFG S+GKS V+N ++ + + S + T+CF++V +D + YL EGS+ S+ + L H+ ++ L V+VF + +++++ + D PG++ E+ I + LD+D+F+ V TL N EK FF ++ SKP+IF+L N+WD S + + + R ++R + L+ + ++ EA RIFFVSA E+ R ++ + Sbjct: 63 KLSIIGEVLSRRHMKVAFFGRTSSGKSSVINAMLWDKVLPSGIGHITNCFLSVEGTDGDKAYLMTEGSDEK-KSVKTVNQLAHAL--HMDKD----LKAGCLVRVFWPKAKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMEDVRRQHMERCLHFLVEELKVVNALEAQNRIFFVSAKEVLSARKQKAQ 297 HSP 2 Score: 95.9005 bits (237), Expect = 2.885e-20 Identity = 79/294 (26.87%), Postives = 141/294 (47.96%), Query Frame = 2 Query: 143 TFDEEKYDKIFTLNESCESLLSRIRARQLKINNIREILNKSEINVIFVGGVSTGKSKIINSILEEEILPSSIGVTNTKVVRLTGSNNGTSCI--KGCDKEFKDKEA-MYEEVMNVSTDELDGNDNEALIEVVISNPKKPILNDKTFLIDTPGYNGNERAKELVMRTCQVSDIIVFVMT--YVFSDEEKEMFKLISEKTSKLNLFILVNKWDESDSDETFTVKMSKDMIE---GRFVDWFKDYNDTERNTAKSRIFFISAKEQMDSFMEAKEGINE----------YRKEEFKRF 970 T+ + D+I T E L ++ + K++ I E+L++ + V F G S+GKS +IN++L +++LPS IG + + G++ + + +G D++ K +++ D G L+ V K +L D L+D+PG + + + C +D+ V V + EK F ++E+ SK N+FIL N+WD S S+ + + + +E V+ K N E A++RIFF+SAKE + + + +G+ E R +EF+ F Sbjct: 39 TYKNPELDRIAT-----EDDLVEMQGYKDKLSIIGEVLSRRHMKVAFFGRTSSGKSSVINAMLWDKVLPSGIGHITNCFLSVEGTDGDKAYLMTEGSDEKKSVKTVNQLAHALHMDKDLKAG----CLVRVFWPKAKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMEDVRRQHMERCLHFLVEELKVVNALE---AQNRIFFVSAKEVLSARKQKAQGMPESGVALAEGFHARLQEFQNF 320
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Human
Match: MFN1 (mitofusin 1 [Source:HGNC Symbol;Acc:HGNC:18262]) HSP 1 Score: 107.071 bits (266), Expect = 8.712e-23 Identity = 70/244 (28.69%), Postives = 131/244 (53.69%), Query Frame = 2 Query: 1820 KVRFIEGKVKKDSIKISFFGTVSAGKSKVLNTIIGENLFLSAVADTTSCFVAVRKSDRGRHYLRVEGSE--TNFDSLTNLKNKVKELTTHLSENTTGRLDTTKTVQVFL-NIENEIMKNNTEIFDCPGSNNKREVTECIMQQSLDSDIFIFVMTC--TLTNEEKDFFEYQSKLSSKPDIFVLVNKWDKSDQDKTAVTEKSRIKIKREIVNLLTKDGNFSSEEASKRIFFVSALEMFKCRIERKE 2536 K+ I + + +K++FFG S+GKS V+N ++ + + S + T+CF++V +D + YL EGS+ + ++ L + + H+ ++ L V+VF + +++++ + D PG++ E+ I + LD+D+F+ V TL N EK FF ++ SKP+IF+L N+WD S + + + R ++R + L+ + ++ EA RIFFVSA E+ R ++ + Sbjct: 63 KLSIIGEVLSRRHMKVAFFGRTSSGKSSVINAMLWDKVLPSGIGHITNCFLSVEGTDGDKAYLMTEGSDEKKSVKTVNQLAHAL-----HMDKD----LKAGCLVRVFWPKAKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMEDVRRQHMERCLHFLVEELKVVNALEAQNRIFFVSAKEVLSARKQKAQ 297 HSP 2 Score: 96.6709 bits (239), Expect = 1.591e-19 Identity = 79/294 (26.87%), Postives = 141/294 (47.96%), Query Frame = 2 Query: 143 TFDEEKYDKIFTLNESCESLLSRIRARQLKINNIREILNKSEINVIFVGGVSTGKSKIINSILEEEILPSSIGVTNTKVVRLTGSNNGTSCI--KGCDKEFKDKEA-MYEEVMNVSTDELDGNDNEALIEVVISNPKKPILNDKTFLIDTPGYNGNERAKELVMRTCQVSDIIVFVMT--YVFSDEEKEMFKLISEKTSKLNLFILVNKWDESDSDETFTVKMSKDMIE---GRFVDWFKDYNDTERNTAKSRIFFISAKEQMDSFMEAKEGINE----------YRKEEFKRF 970 T+ + D+I T E L ++ + K++ I E+L++ + V F G S+GKS +IN++L +++LPS IG + + G++ + + +G D++ K +++ D G L+ V K +L D L+D+PG + + + C +D+ V V + EK F ++E+ SK N+FIL N+WD S S+ + + + +E V+ K N E A++RIFF+SAKE + + + +G+ E R +EF+ F Sbjct: 39 TYKNPELDRIAT-----EDDLVEMQGYKDKLSIIGEVLSRRHMKVAFFGRTSSGKSSVINAMLWDKVLPSGIGHITNCFLSVEGTDGDKAYLMTEGSDEKKSVKTVNQLAHALHMDKDLKAG----CLVRVFWPKAKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMEDVRRQHMERCLHFLVEELKVVNALE---AQNRIFFVSAKEVLSARKQKAQGMPESGVALAEGFHARLQEFQNF 320
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Human
Match: MFN1 (mitofusin 1 [Source:HGNC Symbol;Acc:HGNC:18262]) HSP 1 Score: 107.071 bits (266), Expect = 8.712e-23 Identity = 70/244 (28.69%), Postives = 131/244 (53.69%), Query Frame = 2 Query: 1820 KVRFIEGKVKKDSIKISFFGTVSAGKSKVLNTIIGENLFLSAVADTTSCFVAVRKSDRGRHYLRVEGSE--TNFDSLTNLKNKVKELTTHLSENTTGRLDTTKTVQVFL-NIENEIMKNNTEIFDCPGSNNKREVTECIMQQSLDSDIFIFVMTC--TLTNEEKDFFEYQSKLSSKPDIFVLVNKWDKSDQDKTAVTEKSRIKIKREIVNLLTKDGNFSSEEASKRIFFVSALEMFKCRIERKE 2536 K+ I + + +K++FFG S+GKS V+N ++ + + S + T+CF++V +D + YL EGS+ + ++ L + + H+ ++ L V+VF + +++++ + D PG++ E+ I + LD+D+F+ V TL N EK FF ++ SKP+IF+L N+WD S + + + R ++R + L+ + ++ EA RIFFVSA E+ R ++ + Sbjct: 63 KLSIIGEVLSRRHMKVAFFGRTSSGKSSVINAMLWDKVLPSGIGHITNCFLSVEGTDGDKAYLMTEGSDEKKSVKTVNQLAHAL-----HMDKD----LKAGCLVRVFWPKAKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMEDVRRQHMERCLHFLVEELKVVNALEAQNRIFFVSAKEVLSARKQKAQ 297 HSP 2 Score: 96.6709 bits (239), Expect = 1.591e-19 Identity = 79/294 (26.87%), Postives = 141/294 (47.96%), Query Frame = 2 Query: 143 TFDEEKYDKIFTLNESCESLLSRIRARQLKINNIREILNKSEINVIFVGGVSTGKSKIINSILEEEILPSSIGVTNTKVVRLTGSNNGTSCI--KGCDKEFKDKEA-MYEEVMNVSTDELDGNDNEALIEVVISNPKKPILNDKTFLIDTPGYNGNERAKELVMRTCQVSDIIVFVMT--YVFSDEEKEMFKLISEKTSKLNLFILVNKWDESDSDETFTVKMSKDMIE---GRFVDWFKDYNDTERNTAKSRIFFISAKEQMDSFMEAKEGINE----------YRKEEFKRF 970 T+ + D+I T E L ++ + K++ I E+L++ + V F G S+GKS +IN++L +++LPS IG + + G++ + + +G D++ K +++ D G L+ V K +L D L+D+PG + + + C +D+ V V + EK F ++E+ SK N+FIL N+WD S S+ + + + +E V+ K N E A++RIFF+SAKE + + + +G+ E R +EF+ F Sbjct: 39 TYKNPELDRIAT-----EDDLVEMQGYKDKLSIIGEVLSRRHMKVAFFGRTSSGKSSVINAMLWDKVLPSGIGHITNCFLSVEGTDGDKAYLMTEGSDEKKSVKTVNQLAHALHMDKDLKAG----CLVRVFWPKAKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMEDVRRQHMERCLHFLVEELKVVNALE---AQNRIFFVSAKEVLSARKQKAQGMPESGVALAEGFHARLQEFQNF 320
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Celegans
Match: fzo-1 (Transmembrane GTPase fzo-1 [Source:UniProtKB/Swiss-Prot;Acc:Q23424]) HSP 1 Score: 97.4413 bits (241), Expect = 3.723e-20 Identity = 68/254 (26.77%), Postives = 127/254 (50.00%), Query Frame = 2 Query: 1805 EIIETKVRFIEGKVKKDSIKISFFGTVSAGKSKVLNTIIGENLFLSAVADTTSCFVAVRKSDRGRHYLRVEGSETNFD--SLTNLKNKVKELTTHLSENTTGRLDTTKTVQVFLNIENE-----IMKNNTEIFDCPGSNNKREVTECIMQQSLDSDIFIFVMTC--TLTNEEKDFFEYQSKLSSKPDIFVLVNKWDKSDQDKTAVTEKSRIKIKREIVNLLTKDGNFSSEEASKRIFFVSALEMFKCRIERKEI 2539 E I ++ I ++D++K+ FFG S GKS +N ++ E + + TT CF+ V S+ +L+++ + D L + + + + + L + ++VF ++E +++N+ I D PG + E I + LD+D+F+ V TLT EK+FF +K SKP++F+L N+WD S + + + + + R L+ + S E + RIFFVS+ E+ + R++ + + Sbjct: 83 EAIGDSIKTIMDTFQRDNMKVVFFGRTSNGKSTTINAMLHEKVLPQGMGHTTCCFLQVEGSEGEVGHLQLDDNPQKIDMKMLGKIGHALSDENSDLPA-----MGQDSLLKVFHPKKSESGECRLLQNDVVILDSPGVDLSPEFDSWIDKHCLDADVFVLVSNAESTLTQAEKNFFLRVAKKLSKPNVFILNNRWDASAAETENIEDVKKQHLTRFRQFLVDELEVCSEREVNDRIFFVSSREVLESRLKARGL 331 HSP 2 Score: 87.0409 bits (214), Expect = 5.713e-17 Identity = 68/245 (27.76%), Postives = 122/245 (49.80%), Query Frame = 2 Query: 233 INNIREILNKSEINVIFVGGVSTGKSKIINSILEEEILPSSIGVTNTKVVRLTGSNNGTSCIKGCDKEFKDKEAMYEEVMNVSTDE---LDGNDNEALIEVVISNPKKP------ILNDKTFLIDTPGYNGNERAKELVMRTCQVSDIIVFVMTY--VFSDEEKEMFKLISEKTSKLNLFILVNKWDESDSDETFTVKMSKDMIEGRFVDWFKDYND--TERNTAKSRIFFISAKEQMDSFMEAK 928 I I + + + V+F G S GKS IN++L E++LP +G T +++ GS ++ D K M ++ + +DE L ++L++V +PKK +L + ++D+PG + + + + C +D+ V V + EK F +++K SK N+FIL N+WD S + ET ++ K RF + D + +ER RIFF+S++E ++S ++A+ Sbjct: 89 IKTIMDTFQRDNMKVVFFGRTSNGKSTTINAMLHEKVLPQGMGHTTCCFLQVEGSEGEVGHLQLDDNPQKIDMKMLGKIGHALSDENSDLPAMGQDSLLKVF--HPKKSESGECRLLQNDVVILDSPGVDLSPEFDSWIDKHCLDADVFVLVSNAESTLTQAEKNFFLRVAKKLSKPNVFILNNRWDAS-AAETENIEDVKKQHLTRFRQFLVDELEVCSEREV-NDRIFFVSSREVLESRLKAR 329
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Fly
Match: Marf (gene:FBgn0029870 transcript:FBtr0343373) HSP 1 Score: 129.413 bits (324), Expect = 5.950e-30 Identity = 87/265 (32.83%), Postives = 145/265 (54.72%), Query Frame = 2 Query: 1820 KVRFIEGKVKKDSIKISFFGTVSAGKSKVLNTIIGENLFLSAVADTTSCFVAVRKSDRGRHYLRVEGSETNFDSLTNLKNKVKELTTHLSENTTGRLDTTKTVQVFLNIEN-EIMKNNTEIFDCPGSNNKREVTECIMQQSLDSDIFIFVMTC--TLTNEEKDFFEYQSKLSSKPDIFVLVNKWDKS-DQDKTAVTEKSRIKIKR--EIVNLLTKDGNFSSE-EASKRIFFVSALEMFKCRIERKEIFGNQRTRRAI----EMRY 2581 KV I +++D +K++FFG S GKS V+N ++ E + S + TT+CF V S+ G YL EGSE + + +K+L L + +L + V++F E +++++ D PG + + + I L++D+F+ V+ T+T EK FF S+ SKP+IF+L N+WD S ++ + +E +++K + ++ LTK+ S+E EA++R+FFVSA E + RIE E GN AI ++RY Sbjct: 125 KVAAIREVLQRDHMKVAFFGRTSNGKSSVINAMLREKILPSGIGHTTNCFCQVEGSNGGEAYLMTEGSEEKLNVVN-----IKQLANALCQE---KLCESSLVRIFWPRERCSLLRDDVVFVDSPGVDVSANLDDWIDNHCLNADVFVLVLNAESTMTRAEKQFFHTVSQKLSKPNIFILNNRWDASANEPECQESELAKVKSQHTERCIDFLTKELKVSNEKEAAERVFFVSARETLQARIE--EAKGNPPHMGAIAEGFQIRY 379 HSP 2 Score: 105.145 bits (261), Expect = 1.785e-22 Identity = 71/242 (29.34%), Postives = 120/242 (49.59%), Query Frame = 2 Query: 230 KINNIREILNKSEINVIFVGGVSTGKSKIINSILEEEILPSSIGVTNTKVVRLTGSNNGTSCIKGCDKEFKDKEAMYEEVMNVSTDELDGNDNEALIEVVISNPKKPILNDKTFLIDTPGYNGNERAKELVMRTCQVSDIIVFVMTY--VFSDEEKEMFKLISEKTSKLNLFILVNKWD----ESDSDETFTVKMSKDMIEGRFVDWF-KDYNDTERNTAKSRIFFISAKEQMDSFMEAKEG 934 K+ IRE+L + + V F G S GKS +IN++L E+ILPS IG T ++ GSN G + + E K +++ N E +L+ + + +L D +D+PG + + + + C +D+ V V+ + EK+ F +S+K SK N+FIL N+WD E + E+ K+ E R +D+ K+ + A R+FF+SA+E + + +E +G Sbjct: 125 KVAAIREVLQRDHMKVAFFGRTSNGKSSVINAMLREKILPSGIGHTTNCFCQVEGSNGGEAYLMTEGSEEKLNVVNIKQLANALCQEKLCES--SLVRIFWPRERCSLLRDDVVFVDSPGVDVSANLDDWIDNHCLNADVFVLVLNAESTMTRAEKQFFHTVSQKLSKPNIFILNNRWDASANEPECQESELAKVKSQHTE-RCIDFLTKELKVSNEKEAAERVFFVSARETLQARIEEAKG 363
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Fly
Match: Marf (gene:FBgn0029870 transcript:FBtr0070910) HSP 1 Score: 128.257 bits (321), Expect = 1.116e-29 Identity = 86/262 (32.82%), Postives = 140/262 (53.44%), Query Frame = 2 Query: 1820 KVRFIEGKVKKDSIKISFFGTVSAGKSKVLNTIIGENLFLSAVADTTSCFVAVRKSDRGRHYLRVEGSETNFDSLTNLKNKVKELTTHLSENTTGRLDTTKTVQVFLNIEN-EIMKNNTEIFDCPGSNNKREVTECIMQQSLDSDIFIFVMTC--TLTNEEKDFFEYQSKLSSKPDIFVLVNKWDKSDQDKTAVTEKSRIKIKREIVNLLTKDGNFSSE-EASKRIFFVSALEMFKCRIERKEIFGNQRTRRAI----EMRY 2581 KV I +++D +K++FFG S GKS V+N ++ E + S + TT+CF V S+ G YL EGSE + + +K+L L + +L + V++F E +++++ D PG + + + I L++D+F+ V+ T+T EK FF S+ SKP+IF+L N+WD S ++ E + + ++ LTK+ S+E EA++R+FFVSA E + RIE E GN AI ++RY Sbjct: 125 KVAAIREVLQRDHMKVAFFGRTSNGKSSVINAMLREKILPSGIGHTTNCFCQVEGSNGGEAYLMTEGSEEKLNVVN-----IKQLANALCQE---KLCESSLVRIFWPRERCSLLRDDVVFVDSPGVDVSANLDDWIDNHCLNADVFVLVLNAESTMTRAEKQFFHTVSQKLSKPNIFILNNRWDAS-ANEPECQESVKSQHTERCIDFLTKELKVSNEKEAAERVFFVSARETLQARIE--EAKGNPPHMGAIAEGFQIRY 375 HSP 2 Score: 104.76 bits (260), Expect = 2.415e-22 Identity = 69/238 (28.99%), Postives = 118/238 (49.58%), Query Frame = 2 Query: 230 KINNIREILNKSEINVIFVGGVSTGKSKIINSILEEEILPSSIGVTNTKVVRLTGSNNGTSCIKGCDKEFKDKEAMYEEVMNVSTDELDGNDNEALIEVVISNPKKPILNDKTFLIDTPGYNGNERAKELVMRTCQVSDIIVFVMTY--VFSDEEKEMFKLISEKTSKLNLFILVNKWDESDSDETFTVKMSKDMIEGRFVDWF-KDYNDTERNTAKSRIFFISAKEQMDSFMEAKEG 934 K+ IRE+L + + V F G S GKS +IN++L E+ILPS IG T ++ GSN G + + E K +++ N E +L+ + + +L D +D+PG + + + + C +D+ V V+ + EK+ F +S+K SK N+FIL N+WD S ++ + E R +D+ K+ + A R+FF+SA+E + + +E +G Sbjct: 125 KVAAIREVLQRDHMKVAFFGRTSNGKSSVINAMLREKILPSGIGHTTNCFCQVEGSNGGEAYLMTEGSEEKLNVVNIKQLANALCQEKLCES--SLVRIFWPRERCSLLRDDVVFVDSPGVDVSANLDDWIDNHCLNADVFVLVLNAESTMTRAEKQFFHTVSQKLSKPNIFILNNRWDASANEPECQESVKSQHTE-RCIDFLTKELKVSNEKEAAERVFFVSARETLQARIEEAKG 359
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Fly
Match: Marf (gene:FBgn0029870 transcript:FBtr0070909) HSP 1 Score: 128.257 bits (321), Expect = 1.116e-29 Identity = 86/262 (32.82%), Postives = 140/262 (53.44%), Query Frame = 2 Query: 1820 KVRFIEGKVKKDSIKISFFGTVSAGKSKVLNTIIGENLFLSAVADTTSCFVAVRKSDRGRHYLRVEGSETNFDSLTNLKNKVKELTTHLSENTTGRLDTTKTVQVFLNIEN-EIMKNNTEIFDCPGSNNKREVTECIMQQSLDSDIFIFVMTC--TLTNEEKDFFEYQSKLSSKPDIFVLVNKWDKSDQDKTAVTEKSRIKIKREIVNLLTKDGNFSSE-EASKRIFFVSALEMFKCRIERKEIFGNQRTRRAI----EMRY 2581 KV I +++D +K++FFG S GKS V+N ++ E + S + TT+CF V S+ G YL EGSE + + +K+L L + +L + V++F E +++++ D PG + + + I L++D+F+ V+ T+T EK FF S+ SKP+IF+L N+WD S ++ E + + ++ LTK+ S+E EA++R+FFVSA E + RIE E GN AI ++RY Sbjct: 125 KVAAIREVLQRDHMKVAFFGRTSNGKSSVINAMLREKILPSGIGHTTNCFCQVEGSNGGEAYLMTEGSEEKLNVVN-----IKQLANALCQE---KLCESSLVRIFWPRERCSLLRDDVVFVDSPGVDVSANLDDWIDNHCLNADVFVLVLNAESTMTRAEKQFFHTVSQKLSKPNIFILNNRWDAS-ANEPECQESVKSQHTERCIDFLTKELKVSNEKEAAERVFFVSARETLQARIE--EAKGNPPHMGAIAEGFQIRY 375 HSP 2 Score: 104.76 bits (260), Expect = 2.415e-22 Identity = 69/238 (28.99%), Postives = 118/238 (49.58%), Query Frame = 2 Query: 230 KINNIREILNKSEINVIFVGGVSTGKSKIINSILEEEILPSSIGVTNTKVVRLTGSNNGTSCIKGCDKEFKDKEAMYEEVMNVSTDELDGNDNEALIEVVISNPKKPILNDKTFLIDTPGYNGNERAKELVMRTCQVSDIIVFVMTY--VFSDEEKEMFKLISEKTSKLNLFILVNKWDESDSDETFTVKMSKDMIEGRFVDWF-KDYNDTERNTAKSRIFFISAKEQMDSFMEAKEG 934 K+ IRE+L + + V F G S GKS +IN++L E+ILPS IG T ++ GSN G + + E K +++ N E +L+ + + +L D +D+PG + + + + C +D+ V V+ + EK+ F +S+K SK N+FIL N+WD S ++ + E R +D+ K+ + A R+FF+SA+E + + +E +G Sbjct: 125 KVAAIREVLQRDHMKVAFFGRTSNGKSSVINAMLREKILPSGIGHTTNCFCQVEGSNGGEAYLMTEGSEEKLNVVNIKQLANALCQEKLCES--SLVRIFWPRERCSLLRDDVVFVDSPGVDVSANLDDWIDNHCLNADVFVLVLNAESTMTRAEKQFFHTVSQKLSKPNIFILNNRWDASANEPECQESVKSQHTE-RCIDFLTKELKVSNEKEAAERVFFVSARETLQARIEEAKG 359
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Fly
Match: fzo (gene:FBgn0011596 transcript:FBtr0084399) HSP 1 Score: 109.768 bits (273), Expect = 6.320e-24 Identity = 69/241 (28.63%), Postives = 130/241 (53.94%), Query Frame = 2 Query: 1817 TKVRFIEGKVKKDSIKISFFGTVSAGKSKVLNTIIGENLFLSAVADTTSCFVAVRKSDRGR-HYLRVEGSETNFDSLTNLKNKVKELTTHLSENTTGRLDTTKTVQVFLNIEN-EIMKNNTEIFDCPGSNNKREVTECIMQQSLDSDIFIFVMTC--TLTNEEKDFFEYQSKLSSKPDIFVLVNKWDKSDQDKTAVTEKSRIKIKREIVNLLTKD-GNFS-SEEASKRIFFVSALEMFKCR 2521 ++V I + +D +K++FFG S GKS V+N ++ E + SA+ TTSCF V+ + +++VE + + + + L+ S ++ G L + +QV + I+ + + D PG + ++ +C+ +D+D+FI V+ T++ E+ FF+ + S+P++F+L N+WDK+ + + +K + + VNLL + G +S ++EA +RI+ VSALE R Sbjct: 73 SRVEAIAKVLSRDRMKVAFFGRTSNGKSAVINALLHEKILPSAMGHTTSCFCQVQANGSNETEHVKVEQEDEHME--------LSALSQLASAHSPGALKPSTLLQVNMAKNRCSILDYDVVLMDTPGVDVTAQLDDCLDSYCMDADVFILVLNAESTVSRVERQFFKDVASKLSRPNLFILNNRWDKASSLEPEMEQKVKDQHMERCVNLLVDELGVYSTAQEAWERIYHVSALEALHIR 305 HSP 2 Score: 95.1301 bits (235), Expect = 2.254e-19 Identity = 73/276 (26.45%), Postives = 137/276 (49.64%), Query Frame = 2 Query: 200 LLSRIRARQLKINNIREILNKSEINVIFVGGVSTGKSKIINSILEEEILPSSIGVTNTKVVRLTGSNNGTSCIKGCDKEFKDKEAMYEEVMNVSTDELDGN-DNEALIEVVISNPKKPILNDKTFLIDTPGYNGNERAKELVMRTCQVSDIIVFVMTY--VFSDEEKEMFKLISEKTSKLNLFILVNKWDESDSDETFTVKMSKDMIEGRFVDWFKD----YNDTERNTAKSRIFFISAKEQM---DSFMEAKEGINEYRKEEFKRFITELNKSLS 997 +L + A ++ I ++L++ + V F G S GKS +IN++L E+ILPS++G T + ++ NG++ + E +D+ + +++ G L++V ++ + IL+ L+DTPG + + + + C +D+ + V+ S E++ FK ++ K S+ NLFIL N+WD++ S E + KD R V+ D Y+ + A RI+ +SA E + + + G + R +EF RF + + L+ Sbjct: 64 MLEHLCAFSSRVEAIAKVLSRDRMKVAFFGRTSNGKSAVINALLHEKILPSAMGHTTSCFCQVQA--NGSNETEHVKVEQEDEHMELSALSQLASAHSPGALKPSTLLQVNMAKNRCSILDYDVVLMDTPGVDVTAQLDDCLDSYCMDADVFILVLNAESTVSRVERQFFKDVASKLSRPNLFILNNRWDKASSLEPEMEQKVKDQHMERCVNLLVDELGVYSTAQE--AWERIYHVSALEALHIRNGQITNPSGQTQQRYQEFLRFENDFSNCLA 335
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Zebrafish
Match: mfn1b (mitofusin 1b [Source:ZFIN;Acc:ZDB-GENE-040426-1553]) HSP 1 Score: 112.849 bits (281), Expect = 1.951e-26 Identity = 80/262 (30.53%), Postives = 139/262 (53.05%), Query Frame = 2 Query: 1778 TIENFVKKYEIIE-----TKVRFIEGKVKKDSIKISFFGTVSAGKSKVLNTIIGENLFLSAVADTTSCFVAVRKSDRGRHYLRVEGSETNFDSLTNLKNKVKELTTHLSENTTGRLDTTKTVQVFL-NIENEIMKNNTEIFDCPGSNNKREVTECIMQQSLDSDIFIFVMT--CTLTNEEKDFFEYQSKLSSKPDIFVLVNKWDKSDQDKTAVTEKSRIKIKREIVNLLTKDGN-FSSEEASKRIFFVSALEMFKCRIERKE 2536 ++EN K ++ E +K+ I+ + + +K++FFG S GKS V+N ++ + + S + TT+CF++V +D + +L+ EGSE S+ + L H+ E+ LD V+VF + +++++ + D PG++ E+ I + LD+D+F+ V TL N EK FF ++ SKP+IF+L N+WD S + + E R + VN L ++ +A RIFFVSA E+ R++R + Sbjct: 45 SLENIANKDQLDEIESYTSKLSIIQEVLARRHMKVAFFGRTSNGKSTVINAMLRDRVLPSGIGHTTNCFLSVEGTDEDKAFLKTEGSEEE-KSIKTVNQLAHAL--HMDES----LDAGCLVKVFWPKTKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNEKLSKPNIFILNNRWDASAAEPEYM-EDVRKQHTDRCVNFLVEELKVVDRAQAPNRIFFVSAKEVLNSRMQRAQ 298 HSP 2 Score: 105.145 bits (261), Expect = 8.986e-24 Identity = 78/261 (29.89%), Postives = 135/261 (51.72%), Query Frame = 2 Query: 182 NESCESL-----LSRIRARQLKINNIREILNKSEINVIFVGGVSTGKSKIINSILEEEILPSSIGVTNTKVVRLTGSNNGTSCIK--GCDKEFKDKEAMYEEVMNVSTDELDGNDNEALIEVVISNPKKPILNDKTFLIDTPGYNGNERAKELVMRTCQVSDIIVFVMT--YVFSDEEKEMFKLISEKTSKLNLFILVNKWDESDSDETFTVKMSKDMIEGRFVDWF-KDYNDTERNTAKSRIFFISAKEQMDSFMEAKEG 934 NES E++ L I + K++ I+E+L + + V F G S GKS +IN++L + +LPS IG T + + G++ + +K G ++E K + + + + DE D L++V K +L D L+D+PG + + + C +D+ V V + EK F ++EK SK N+FIL N+WD S ++ + + K + R V++ ++ +R A +RIFF+SAKE ++S M+ +G Sbjct: 43 NESLENIANKDQLDEIESYTSKLSIIQEVLARRHMKVAFFGRTSNGKSTVINAMLRDRVLPSGIGHTTNCFLSVEGTDEDKAFLKTEGSEEE-KSIKTVNQLAHALHMDE--SLDAGCLVKVFWPKTKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNEKLSKPNIFILNNRWDASAAEPEYMEDVRKQHTD-RCVNFLVEELKVVDRAQAPNRIFFVSAKEVLNSRMQRAQG 299
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Zebrafish
Match: mfn1b (mitofusin 1b [Source:ZFIN;Acc:ZDB-GENE-040426-1553]) HSP 1 Score: 113.235 bits (282), Expect = 1.954e-26 Identity = 80/262 (30.53%), Postives = 139/262 (53.05%), Query Frame = 2 Query: 1778 TIENFVKKYEIIE-----TKVRFIEGKVKKDSIKISFFGTVSAGKSKVLNTIIGENLFLSAVADTTSCFVAVRKSDRGRHYLRVEGSETNFDSLTNLKNKVKELTTHLSENTTGRLDTTKTVQVFL-NIENEIMKNNTEIFDCPGSNNKREVTECIMQQSLDSDIFIFVMT--CTLTNEEKDFFEYQSKLSSKPDIFVLVNKWDKSDQDKTAVTEKSRIKIKREIVNLLTKDGN-FSSEEASKRIFFVSALEMFKCRIERKE 2536 ++EN K ++ E +K+ I+ + + +K++FFG S GKS V+N ++ + + S + TT+CF++V +D + +L+ EGSE S+ + L H+ E+ LD V+VF + +++++ + D PG++ E+ I + LD+D+F+ V TL N EK FF ++ SKP+IF+L N+WD S + + E R + VN L ++ +A RIFFVSA E+ R++R + Sbjct: 45 SLENIANKDQLDEIESYTSKLSIIQEVLARRHMKVAFFGRTSNGKSTVINAMLRDRVLPSGIGHTTNCFLSVEGTDEDKAFLKTEGSEEE-KSIKTVNQLAHAL--HMDES----LDAGCLVKVFWPKTKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNEKLSKPNIFILNNRWDASAAEPEYM-EDVRKQHTDRCVNFLVEELKVVDRAQAPNRIFFVSAKEVLNSRMQRAQ 298 HSP 2 Score: 107.071 bits (266), Expect = 2.506e-24 Identity = 80/269 (29.74%), Postives = 134/269 (49.81%), Query Frame = 2 Query: 182 NESCESL-----LSRIRARQLKINNIREILNKSEINVIFVGGVSTGKSKIINSILEEEILPSSIGVTNTKVVRLTGSNNGTSCIKGCDKEFKDKEAMYEEVMNVSTDEL-------DGNDNEALIEVVISNPKKPILNDKTFLIDTPGYNGNERAKELVMRTCQVSDIIVFVMT--YVFSDEEKEMFKLISEKTSKLNLFILVNKWDESDSDETFTVKMSKDMIEGRFVDWF-KDYNDTERNTAKSRIFFISAKEQMDSFMEAKEGINE 943 NES E++ L I + K++ I+E+L + + V F G S GKS +IN++L + +LPS IG T + + G++ DK F E EE + ++L + D L++V K +L D L+D+PG + + + C +D+ V V + EK F ++EK SK N+FIL N+WD S ++ + + K + R V++ ++ +R A +RIFF+SAKE ++S M+ +G+ E Sbjct: 43 NESLENIANKDQLDEIESYTSKLSIIQEVLARRHMKVAFFGRTSNGKSTVINAMLRDRVLPSGIGHTTNCFLSVEGTDE--------DKAFLKTEGSEEEKSIKTVNQLAHALHMDESLDAGCLVKVFWPKTKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNEKLSKPNIFILNNRWDASAAEPEYMEDVRKQHTD-RCVNFLVEELKVVDRAQAPNRIFFVSAKEVLNSRMQRAQGMPE 302
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Zebrafish
Match: mfn1b (mitofusin 1b [Source:ZFIN;Acc:ZDB-GENE-040426-1553]) HSP 1 Score: 112.849 bits (281), Expect = 8.155e-25 Identity = 79/264 (29.92%), Postives = 141/264 (53.41%), Query Frame = 2 Query: 1778 TIENFVKKYEIIE-----TKVRFIEGKVKKDSIKISFFGTVSAGKSKVLNTIIGENLFLSAVADTTSCFVAVRKSDRGRHYLRVEGS--ETNFDSLTNLKNKVKELTTHLSENTTGRLDTTKTVQVFL-NIENEIMKNNTEIFDCPGSNNKREVTECIMQQSLDSDIFIFVMT--CTLTNEEKDFFEYQSKLSSKPDIFVLVNKWDKSDQDKTAVTEKSRIKIKREIVNLLTKDGN-FSSEEASKRIFFVSALEMFKCRIERKE 2536 ++EN K ++ E +K+ I+ + + +K++FFG S GKS V+N ++ + + S + TT+CF++V +D + +L+ EGS E + ++ L + + H+ E+ LD V+VF + +++++ + D PG++ E+ I + LD+D+F+ V TL N EK FF ++ SKP+IF+L N+WD S + + E R + VN L ++ +A RIFFVSA E+ R++R + Sbjct: 45 SLENIANKDQLDEIESYTSKLSIIQEVLARRHMKVAFFGRTSNGKSTVINAMLRDRVLPSGIGHTTNCFLSVEGTDEDKAFLKTEGSEEEKSIKTVNQLAHAL-----HMDES----LDAGCLVKVFWPKTKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNEKLSKPNIFILNNRWDASAAEPEYM-EDVRKQHTDRCVNFLVEELKVVDRAQAPNRIFFVSAKEVLNSRMQRAQ 298 HSP 2 Score: 107.457 bits (267), Expect = 3.698e-23 Identity = 80/269 (29.74%), Postives = 134/269 (49.81%), Query Frame = 2 Query: 182 NESCESL-----LSRIRARQLKINNIREILNKSEINVIFVGGVSTGKSKIINSILEEEILPSSIGVTNTKVVRLTGSNNGTSCIKGCDKEFKDKEAMYEEVMNVSTDEL-------DGNDNEALIEVVISNPKKPILNDKTFLIDTPGYNGNERAKELVMRTCQVSDIIVFVMT--YVFSDEEKEMFKLISEKTSKLNLFILVNKWDESDSDETFTVKMSKDMIEGRFVDWF-KDYNDTERNTAKSRIFFISAKEQMDSFMEAKEGINE 943 NES E++ L I + K++ I+E+L + + V F G S GKS +IN++L + +LPS IG T + + G++ DK F E EE + ++L + D L++V K +L D L+D+PG + + + C +D+ V V + EK F ++EK SK N+FIL N+WD S ++ + + K + R V++ ++ +R A +RIFF+SAKE ++S M+ +G+ E Sbjct: 43 NESLENIANKDQLDEIESYTSKLSIIQEVLARRHMKVAFFGRTSNGKSTVINAMLRDRVLPSGIGHTTNCFLSVEGTDE--------DKAFLKTEGSEEEKSIKTVNQLAHALHMDESLDAGCLVKVFWPKTKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNEKLSKPNIFILNNRWDASAAEPEYMEDVRKQHTD-RCVNFLVEELKVVDRAQAPNRIFFVSAKEVLNSRMQRAQGMPE 302
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Zebrafish
Match: mfn1b (mitofusin 1b [Source:ZFIN;Acc:ZDB-GENE-040426-1553]) HSP 1 Score: 112.849 bits (281), Expect = 8.155e-25 Identity = 79/264 (29.92%), Postives = 141/264 (53.41%), Query Frame = 2 Query: 1778 TIENFVKKYEIIE-----TKVRFIEGKVKKDSIKISFFGTVSAGKSKVLNTIIGENLFLSAVADTTSCFVAVRKSDRGRHYLRVEGS--ETNFDSLTNLKNKVKELTTHLSENTTGRLDTTKTVQVFL-NIENEIMKNNTEIFDCPGSNNKREVTECIMQQSLDSDIFIFVMT--CTLTNEEKDFFEYQSKLSSKPDIFVLVNKWDKSDQDKTAVTEKSRIKIKREIVNLLTKDGN-FSSEEASKRIFFVSALEMFKCRIERKE 2536 ++EN K ++ E +K+ I+ + + +K++FFG S GKS V+N ++ + + S + TT+CF++V +D + +L+ EGS E + ++ L + + H+ E+ LD V+VF + +++++ + D PG++ E+ I + LD+D+F+ V TL N EK FF ++ SKP+IF+L N+WD S + + E R + VN L ++ +A RIFFVSA E+ R++R + Sbjct: 45 SLENIANKDQLDEIESYTSKLSIIQEVLARRHMKVAFFGRTSNGKSTVINAMLRDRVLPSGIGHTTNCFLSVEGTDEDKAFLKTEGSEEEKSIKTVNQLAHAL-----HMDES----LDAGCLVKVFWPKTKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNEKLSKPNIFILNNRWDASAAEPEYM-EDVRKQHTDRCVNFLVEELKVVDRAQAPNRIFFVSAKEVLNSRMQRAQ 298 HSP 2 Score: 107.457 bits (267), Expect = 3.698e-23 Identity = 80/269 (29.74%), Postives = 134/269 (49.81%), Query Frame = 2 Query: 182 NESCESL-----LSRIRARQLKINNIREILNKSEINVIFVGGVSTGKSKIINSILEEEILPSSIGVTNTKVVRLTGSNNGTSCIKGCDKEFKDKEAMYEEVMNVSTDEL-------DGNDNEALIEVVISNPKKPILNDKTFLIDTPGYNGNERAKELVMRTCQVSDIIVFVMT--YVFSDEEKEMFKLISEKTSKLNLFILVNKWDESDSDETFTVKMSKDMIEGRFVDWF-KDYNDTERNTAKSRIFFISAKEQMDSFMEAKEGINE 943 NES E++ L I + K++ I+E+L + + V F G S GKS +IN++L + +LPS IG T + + G++ DK F E EE + ++L + D L++V K +L D L+D+PG + + + C +D+ V V + EK F ++EK SK N+FIL N+WD S ++ + + K + R V++ ++ +R A +RIFF+SAKE ++S M+ +G+ E Sbjct: 43 NESLENIANKDQLDEIESYTSKLSIIQEVLARRHMKVAFFGRTSNGKSTVINAMLRDRVLPSGIGHTTNCFLSVEGTDE--------DKAFLKTEGSEEEKSIKTVNQLAHALHMDESLDAGCLVKVFWPKTKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNEKLSKPNIFILNNRWDASAAEPEYMEDVRKQHTD-RCVNFLVEELKVVDRAQAPNRIFFVSAKEVLNSRMQRAQGMPE 302
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Zebrafish
Match: mfn1b (mitofusin 1b [Source:ZFIN;Acc:ZDB-GENE-040426-1553]) HSP 1 Score: 112.849 bits (281), Expect = 8.775e-25 Identity = 79/264 (29.92%), Postives = 141/264 (53.41%), Query Frame = 2 Query: 1778 TIENFVKKYEIIE-----TKVRFIEGKVKKDSIKISFFGTVSAGKSKVLNTIIGENLFLSAVADTTSCFVAVRKSDRGRHYLRVEGS--ETNFDSLTNLKNKVKELTTHLSENTTGRLDTTKTVQVFL-NIENEIMKNNTEIFDCPGSNNKREVTECIMQQSLDSDIFIFVMT--CTLTNEEKDFFEYQSKLSSKPDIFVLVNKWDKSDQDKTAVTEKSRIKIKREIVNLLTKDGN-FSSEEASKRIFFVSALEMFKCRIERKE 2536 ++EN K ++ E +K+ I+ + + +K++FFG S GKS V+N ++ + + S + TT+CF++V +D + +L+ EGS E + ++ L + + H+ E+ LD V+VF + +++++ + D PG++ E+ I + LD+D+F+ V TL N EK FF ++ SKP+IF+L N+WD S + + E R + VN L ++ +A RIFFVSA E+ R++R + Sbjct: 45 SLENIANKDQLDEIESYTSKLSIIQEVLARRHMKVAFFGRTSNGKSTVINAMLRDRVLPSGIGHTTNCFLSVEGTDEDKAFLKTEGSEEEKSIKTVNQLAHAL-----HMDES----LDAGCLVKVFWPKTKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNEKLSKPNIFILNNRWDASAAEPEYM-EDVRKQHTDRCVNFLVEELKVVDRAQAPNRIFFVSAKEVLNSRMQRAQ 298 HSP 2 Score: 105.916 bits (263), Expect = 1.254e-22 Identity = 78/261 (29.89%), Postives = 135/261 (51.72%), Query Frame = 2 Query: 182 NESCESL-----LSRIRARQLKINNIREILNKSEINVIFVGGVSTGKSKIINSILEEEILPSSIGVTNTKVVRLTGSNNGTSCIK--GCDKEFKDKEAMYEEVMNVSTDELDGNDNEALIEVVISNPKKPILNDKTFLIDTPGYNGNERAKELVMRTCQVSDIIVFVMT--YVFSDEEKEMFKLISEKTSKLNLFILVNKWDESDSDETFTVKMSKDMIEGRFVDWF-KDYNDTERNTAKSRIFFISAKEQMDSFMEAKEG 934 NES E++ L I + K++ I+E+L + + V F G S GKS +IN++L + +LPS IG T + + G++ + +K G ++E K + + + + DE D L++V K +L D L+D+PG + + + C +D+ V V + EK F ++EK SK N+FIL N+WD S ++ + + K + R V++ ++ +R A +RIFF+SAKE ++S M+ +G Sbjct: 43 NESLENIANKDQLDEIESYTSKLSIIQEVLARRHMKVAFFGRTSNGKSTVINAMLRDRVLPSGIGHTTNCFLSVEGTDEDKAFLKTEGSEEE-KSIKTVNQLAHALHMDE--SLDAGCLVKVFWPKTKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNEKLSKPNIFILNNRWDASAAEPEYMEDVRKQHTD-RCVNFLVEELKVVDRAQAPNRIFFVSAKEVLNSRMQRAQG 299
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Xenopus
Match: mfn1 (mitofusin 1 [Source:NCBI gene;Acc:548943]) HSP 1 Score: 111.309 bits (277), Expect = 4.240e-24 Identity = 77/254 (30.31%), Postives = 137/254 (53.94%), Query Frame = 2 Query: 1784 ENFVKKYEIIETKVRFIEGKVKKDSIKISFFGTVSAGKSKVLNTIIGENLFLSAVADTTSCFVAVRKSDRGRHYLRVEGSETNFDSLTNLKNKVKELTTHLSENTTGRLDTTKTVQVFL-NIENEIMKNNTEIFDCPGSNNKREVTECIMQQSLDSDIFIFVMT--CTLTNEEKDFFEYQSKLSSKPDIFVLVNKWDKSDQDKTAVTEKSRIKIKREIVNLLTKDGNFSSEEASKRIFFVSALEMFKCRIERKE 2536 E+ V K + +TK+ I + + ++K++FFG S+GKS V+N+++ + + S + TT+CF++V ++ + YL EGSE S+ + L H+ ++ L V VF + +++++ + D PG++ E+ I + LD+D+F+ V TL N EK FF ++ SKP+IF+L N+WD S + + + + ++R L+ + S EA KRIFFVSA E+ R+ + + Sbjct: 62 EDDVNKVKASKTKLAGIGEVLARRNMKVAFFGRTSSGKSTVINSMLWDKVLPSGIGHTTNCFLSVEGTEGDKAYLMTEGSEEK-KSVKTVNQLAHAL--HMDKD----LGAGCLVHVFWPKAKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFYKVNEKLSKPNIFILNNRWDASASEPEYMEDVRKQHMERCQSFLVDELKVVDSLEAQKRIFFVSAKEVLNARMHKAQ 308 HSP 2 Score: 105.916 bits (263), Expect = 1.598e-22 Identity = 76/259 (29.34%), Postives = 127/259 (49.03%), Query Frame = 2 Query: 182 NESCESLLSRIRARQLKINNIREILNKSEINVIFVGGVSTGKSKIINSILEEEILPSSIGVTNTKVVRLTGSNNGTSCIKGCDKEFKDKEAMYEEVMNVSTDELDGNDNEALIEVVISNPKKPILNDKTFLIDTPGYNGNERAKELVMRTCQVSDIIVFVMT--YVFSDEEKEMFKLISEKTSKLNLFILVNKWDESDSDETFTVKMSKDMIE---GRFVDWFKDYNDTERNTAKSRIFFISAKEQMDSFMEAKEGINE 943 N S E +++++A + K+ I E+L + + V F G S+GKS +INS+L +++LPS IG T + + G+ + + E K ++ + + D L+ V K +L D L+D+PG + + + C +D+ V V + EK F ++EK SK N+FIL N+WD S S+ + + K +E VD K + E A+ RIFF+SAKE +++ M +G+ E Sbjct: 58 NVSTEDDVNKVKASKTKLAGIGEVLARRNMKVAFFGRTSSGKSTVINSMLWDKVLPSGIGHTTNCFLSVEGTEGDKAYLMTEGSEEKKSVKTVNQLAHALHMDKDLGAG-CLVHVFWPKAKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFYKVNEKLSKPNIFILNNRWDASASEPEYMEDVRKQHMERCQSFLVDELKVVDSLE---AQKRIFFVSAKEVLNARMHKAQGMPE 312
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Xenopus
Match: mfn1 (mitofusin 1 [Source:NCBI gene;Acc:548943]) HSP 1 Score: 110.923 bits (276), Expect = 5.502e-24 Identity = 77/256 (30.08%), Postives = 138/256 (53.91%), Query Frame = 2 Query: 1778 TIENFVKKYEIIETKVRFIEGKVKKDSIKISFFGTVSAGKSKVLNTIIGENLFLSAVADTTSCFVAVRKSDRGRHYLRVEGSETNFDSLTNLKNKVKELTTHLSENTTGRLDTTKTVQVFL-NIENEIMKNNTEIFDCPGSNNKREVTECIMQQSLDSDIFIFVMT--CTLTNEEKDFFEYQSKLSSKPDIFVLVNKWDKSDQDKTAVTEKSRIKIKREIVNLLTKDGNFSSEEASKRIFFVSALEMFKCRIERKE 2536 + E+ V K + +TK+ I + + ++K++FFG S+GKS V+N+++ + + S + TT+CF++V ++ + YL EGSE S+ + L H+ ++ L V VF + +++++ + D PG++ E+ I + LD+D+F+ V TL N EK FF ++ SKP+IF+L N+WD S + + + + ++R L+ + S EA KRIFFVSA E+ R+ + + Sbjct: 68 STEDDVNKVKASKTKLAGIGEVLARRNMKVAFFGRTSSGKSTVINSMLWDKVLPSGIGHTTNCFLSVEGTEGDKAYLMTEGSEEK-KSVKTVNQLAHAL--HMDKD----LGAGCLVHVFWPKAKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFYKVNEKLSKPNIFILNNRWDASASEPEYMEDVRKQHMERCQSFLVDELKVVDSLEAQKRIFFVSAKEVLNARMHKAQ 316 HSP 2 Score: 109.383 bits (272), Expect = 1.575e-23 Identity = 80/272 (29.41%), Postives = 132/272 (48.53%), Query Frame = 2 Query: 143 TFDEEKYDKIFTLNESCESLLSRIRARQLKINNIREILNKSEINVIFVGGVSTGKSKIINSILEEEILPSSIGVTNTKVVRLTGSNNGTSCIKGCDKEFKDKEAMYEEVMNVSTDELDGNDNEALIEVVISNPKKPILNDKTFLIDTPGYNGNERAKELVMRTCQVSDIIVFVMT--YVFSDEEKEMFKLISEKTSKLNLFILVNKWDESDSDETFTVKMSKDMIE---GRFVDWFKDYNDTERNTAKSRIFFISAKEQMDSFMEAKEGINE 943 TF EE + N S E +++++A + K+ I E+L + + V F G S+GKS +INS+L +++LPS IG T + + G+ + + E K ++ + + D L+ V K +L D L+D+PG + + + C +D+ V V + EK F ++EK SK N+FIL N+WD S S+ + + K +E VD K + E A+ RIFF+SAKE +++ M +G+ E Sbjct: 53 TFVEETFQNPELKNVSTEDDVNKVKASKTKLAGIGEVLARRNMKVAFFGRTSSGKSTVINSMLWDKVLPSGIGHTTNCFLSVEGTEGDKAYLMTEGSEEKKSVKTVNQLAHALHMDKDLGAG-CLVHVFWPKAKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFYKVNEKLSKPNIFILNNRWDASASEPEYMEDVRKQHMERCQSFLVDELKVVDSLE---AQKRIFFVSAKEVLNARMHKAQGMPE 320
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Xenopus
Match: mfn1 (mitofusin 1 [Source:NCBI gene;Acc:548943]) HSP 1 Score: 110.538 bits (275), Expect = 5.691e-24 Identity = 77/256 (30.08%), Postives = 138/256 (53.91%), Query Frame = 2 Query: 1778 TIENFVKKYEIIETKVRFIEGKVKKDSIKISFFGTVSAGKSKVLNTIIGENLFLSAVADTTSCFVAVRKSDRGRHYLRVEGSETNFDSLTNLKNKVKELTTHLSENTTGRLDTTKTVQVFL-NIENEIMKNNTEIFDCPGSNNKREVTECIMQQSLDSDIFIFVMT--CTLTNEEKDFFEYQSKLSSKPDIFVLVNKWDKSDQDKTAVTEKSRIKIKREIVNLLTKDGNFSSEEASKRIFFVSALEMFKCRIERKE 2536 + E+ V K + +TK+ I + + ++K++FFG S+GKS V+N+++ + + S + TT+CF++V ++ + YL EGSE S+ + L H+ ++ L V VF + +++++ + D PG++ E+ I + LD+D+F+ V TL N EK FF ++ SKP+IF+L N+WD S + + + + ++R L+ + S EA KRIFFVSA E+ R+ + + Sbjct: 50 STEDDVNKVKASKTKLAGIGEVLARRNMKVAFFGRTSSGKSTVINSMLWDKVLPSGIGHTTNCFLSVEGTEGDKAYLMTEGSEEK-KSVKTVNQLAHAL--HMDKD----LGAGCLVHVFWPKAKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFYKVNEKLSKPNIFILNNRWDASASEPEYMEDVRKQHMERCQSFLVDELKVVDSLEAQKRIFFVSAKEVLNARMHKAQ 298 HSP 2 Score: 109.383 bits (272), Expect = 1.675e-23 Identity = 80/272 (29.41%), Postives = 132/272 (48.53%), Query Frame = 2 Query: 143 TFDEEKYDKIFTLNESCESLLSRIRARQLKINNIREILNKSEINVIFVGGVSTGKSKIINSILEEEILPSSIGVTNTKVVRLTGSNNGTSCIKGCDKEFKDKEAMYEEVMNVSTDELDGNDNEALIEVVISNPKKPILNDKTFLIDTPGYNGNERAKELVMRTCQVSDIIVFVMT--YVFSDEEKEMFKLISEKTSKLNLFILVNKWDESDSDETFTVKMSKDMIE---GRFVDWFKDYNDTERNTAKSRIFFISAKEQMDSFMEAKEGINE 943 TF EE + N S E +++++A + K+ I E+L + + V F G S+GKS +INS+L +++LPS IG T + + G+ + + E K ++ + + D L+ V K +L D L+D+PG + + + C +D+ V V + EK F ++EK SK N+FIL N+WD S S+ + + K +E VD K + E A+ RIFF+SAKE +++ M +G+ E Sbjct: 35 TFVEETFQNPELKNVSTEDDVNKVKASKTKLAGIGEVLARRNMKVAFFGRTSSGKSTVINSMLWDKVLPSGIGHTTNCFLSVEGTEGDKAYLMTEGSEEKKSVKTVNQLAHALHMDKDLGAG-CLVHVFWPKAKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFYKVNEKLSKPNIFILNNRWDASASEPEYMEDVRKQHMERCQSFLVDELKVVDSLE---AQKRIFFVSAKEVLNARMHKAQGMPE 302
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Xenopus
Match: mfn1 (mitofusin 1 [Source:NCBI gene;Acc:548943]) HSP 1 Score: 110.538 bits (275), Expect = 5.730e-24 Identity = 77/256 (30.08%), Postives = 138/256 (53.91%), Query Frame = 2 Query: 1778 TIENFVKKYEIIETKVRFIEGKVKKDSIKISFFGTVSAGKSKVLNTIIGENLFLSAVADTTSCFVAVRKSDRGRHYLRVEGSETNFDSLTNLKNKVKELTTHLSENTTGRLDTTKTVQVFL-NIENEIMKNNTEIFDCPGSNNKREVTECIMQQSLDSDIFIFVMT--CTLTNEEKDFFEYQSKLSSKPDIFVLVNKWDKSDQDKTAVTEKSRIKIKREIVNLLTKDGNFSSEEASKRIFFVSALEMFKCRIERKE 2536 + E+ V K + +TK+ I + + ++K++FFG S+GKS V+N+++ + + S + TT+CF++V ++ + YL EGSE S+ + L H+ ++ L V VF + +++++ + D PG++ E+ I + LD+D+F+ V TL N EK FF ++ SKP+IF+L N+WD S + + + + ++R L+ + S EA KRIFFVSA E+ R+ + + Sbjct: 50 STEDDVNKVKASKTKLAGIGEVLARRNMKVAFFGRTSSGKSTVINSMLWDKVLPSGIGHTTNCFLSVEGTEGDKAYLMTEGSEEK-KSVKTVNQLAHAL--HMDKD----LGAGCLVHVFWPKAKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFYKVNEKLSKPNIFILNNRWDASASEPEYMEDVRKQHMERCQSFLVDELKVVDSLEAQKRIFFVSAKEVLNARMHKAQ 298 HSP 2 Score: 108.997 bits (271), Expect = 1.649e-23 Identity = 80/272 (29.41%), Postives = 132/272 (48.53%), Query Frame = 2 Query: 143 TFDEEKYDKIFTLNESCESLLSRIRARQLKINNIREILNKSEINVIFVGGVSTGKSKIINSILEEEILPSSIGVTNTKVVRLTGSNNGTSCIKGCDKEFKDKEAMYEEVMNVSTDELDGNDNEALIEVVISNPKKPILNDKTFLIDTPGYNGNERAKELVMRTCQVSDIIVFVMT--YVFSDEEKEMFKLISEKTSKLNLFILVNKWDESDSDETFTVKMSKDMIE---GRFVDWFKDYNDTERNTAKSRIFFISAKEQMDSFMEAKEGINE 943 TF EE + N S E +++++A + K+ I E+L + + V F G S+GKS +INS+L +++LPS IG T + + G+ + + E K ++ + + D L+ V K +L D L+D+PG + + + C +D+ V V + EK F ++EK SK N+FIL N+WD S S+ + + K +E VD K + E A+ RIFF+SAKE +++ M +G+ E Sbjct: 35 TFVEETFQNPELKNVSTEDDVNKVKASKTKLAGIGEVLARRNMKVAFFGRTSSGKSTVINSMLWDKVLPSGIGHTTNCFLSVEGTEGDKAYLMTEGSEEKKSVKTVNQLAHALHMDKDLGAG-CLVHVFWPKAKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFYKVNEKLSKPNIFILNNRWDASASEPEYMEDVRKQHMERCQSFLVDELKVVDSLE---AQKRIFFVSAKEVLNARMHKAQGMPE 302
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Xenopus
Match: mfn1 (mitofusin 1 [Source:NCBI gene;Acc:548943]) HSP 1 Score: 110.538 bits (275), Expect = 5.904e-24 Identity = 77/256 (30.08%), Postives = 138/256 (53.91%), Query Frame = 2 Query: 1778 TIENFVKKYEIIETKVRFIEGKVKKDSIKISFFGTVSAGKSKVLNTIIGENLFLSAVADTTSCFVAVRKSDRGRHYLRVEGSETNFDSLTNLKNKVKELTTHLSENTTGRLDTTKTVQVFL-NIENEIMKNNTEIFDCPGSNNKREVTECIMQQSLDSDIFIFVMT--CTLTNEEKDFFEYQSKLSSKPDIFVLVNKWDKSDQDKTAVTEKSRIKIKREIVNLLTKDGNFSSEEASKRIFFVSALEMFKCRIERKE 2536 + E+ V K + +TK+ I + + ++K++FFG S+GKS V+N+++ + + S + TT+CF++V ++ + YL EGSE S+ + L H+ ++ L V VF + +++++ + D PG++ E+ I + LD+D+F+ V TL N EK FF ++ SKP+IF+L N+WD S + + + + ++R L+ + S EA KRIFFVSA E+ R+ + + Sbjct: 65 STEDDVNKVKASKTKLAGIGEVLARRNMKVAFFGRTSSGKSTVINSMLWDKVLPSGIGHTTNCFLSVEGTEGDKAYLMTEGSEEK-KSVKTVNQLAHAL--HMDKD----LGAGCLVHVFWPKAKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFYKVNEKLSKPNIFILNNRWDASASEPEYMEDVRKQHMERCQSFLVDELKVVDSLEAQKRIFFVSAKEVLNARMHKAQ 313 HSP 2 Score: 108.997 bits (271), Expect = 1.780e-23 Identity = 80/272 (29.41%), Postives = 132/272 (48.53%), Query Frame = 2 Query: 143 TFDEEKYDKIFTLNESCESLLSRIRARQLKINNIREILNKSEINVIFVGGVSTGKSKIINSILEEEILPSSIGVTNTKVVRLTGSNNGTSCIKGCDKEFKDKEAMYEEVMNVSTDELDGNDNEALIEVVISNPKKPILNDKTFLIDTPGYNGNERAKELVMRTCQVSDIIVFVMT--YVFSDEEKEMFKLISEKTSKLNLFILVNKWDESDSDETFTVKMSKDMIE---GRFVDWFKDYNDTERNTAKSRIFFISAKEQMDSFMEAKEGINE 943 TF EE + N S E +++++A + K+ I E+L + + V F G S+GKS +INS+L +++LPS IG T + + G+ + + E K ++ + + D L+ V K +L D L+D+PG + + + C +D+ V V + EK F ++EK SK N+FIL N+WD S S+ + + K +E VD K + E A+ RIFF+SAKE +++ M +G+ E Sbjct: 50 TFVEETFQNPELKNVSTEDDVNKVKASKTKLAGIGEVLARRNMKVAFFGRTSSGKSTVINSMLWDKVLPSGIGHTTNCFLSVEGTEGDKAYLMTEGSEEKKSVKTVNQLAHALHMDKDLGAG-CLVHVFWPKAKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFYKVNEKLSKPNIFILNNRWDASASEPEYMEDVRKQHMERCQSFLVDELKVVDSLE---AQKRIFFVSAKEVLNARMHKAQGMPE 317
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Mouse
Match: Mfn2 (mitofusin 2 [Source:MGI Symbol;Acc:MGI:2442230]) HSP 1 Score: 114.775 bits (286), Expect = 1.260e-25 Identity = 74/242 (30.58%), Postives = 126/242 (52.07%), Query Frame = 2 Query: 1817 TKVRFIEGKVKKDSIKISFFGTVSAGKSKVLNTIIGENLFLSAVADTTSCFVAVRKSDRGRHYLRVEGSETNFDSLTNLKNKVKELTTHLSENTTGRLDTTKTVQVFLNIENEIMKNNTEIFDCPGSNNKREVTECIMQQSLDSDIFIFVMTC--TLTNEEKDFFEYQSKLSSKPDIFVLVNKWDKSDQDKTAVTEKSRIKIKREIVNLLTKDGNFSSEEASKRIFFVSALEMFKCRIERKE 2536 +KVR I + + +K++FFG S GKS V+N ++ + + S + TT+CF+ V +D +L EGSE T V +L L ++ + +V ++ N + ++K++ + D PG + E+ I + LD+D+F+ V TL EK FF S+ S+P+IF+L N+WD S + + E R ++R L+ + G +A RIFFVSA E+ R+++ + Sbjct: 83 SKVRGISEVLARRHMKVAFFGRTSNGKSTVINAMLWDKVLPSGIGHTTNCFLRVGGTDGHEAFLLTEGSEEKKSVKT-----VNQLAHALHQDEQLHAGSMVSV-MWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKQFFHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHMERCTSFLVDELGVVDRAQAGDRIFFVSAKEVLSARVQKAQ 318 HSP 2 Score: 108.612 bits (270), Expect = 1.114e-23 Identity = 71/243 (29.22%), Postives = 125/243 (51.44%), Query Frame = 2 Query: 230 KINNIREILNKSEINVIFVGGVSTGKSKIINSILEEEILPSSIGVTNTKVVRLTGSNNGTS-CIKGCDKEFKDKEAMYEEVMNVSTDE-LDGNDNEALIEVVISNPKKPILNDKTFLIDTPGYNGNERAKELVMRTCQVSDIIVFVMT--YVFSDEEKEMFKLISEKTSKLNLFILVNKWDESDSDETFTVKMSKDMIEGRFVDWFKD-YNDTERNTAKSRIFFISAKEQMDSFMEAKEGINE 943 K+ I E+L + + V F G S GKS +IN++L +++LPS IG T +R+ G++ + + +E K + + + + DE L +++ V+ N K P+L D L+D+PG + + + C +D+ V V EK+ F +SE+ S+ N+FIL N+WD S S+ + ++ + +E R + D +R A RIFF+SAKE + + ++ +G+ E Sbjct: 84 KVRGISEVLARRHMKVAFFGRTSNGKSTVINAMLWDKVLPSGIGHTTNCFLRVGGTDGHEAFLLTEGSEEKKSVKTVNQLAHALHQDEQLHAG---SMVSVMWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKQFFHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHME-RCTSFLVDELGVVDRAQAGDRIFFVSAKEVLSARVQKAQGMPE 322
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Mouse
Match: Mfn2 (mitofusin 2 [Source:MGI Symbol;Acc:MGI:2442230]) HSP 1 Score: 114.775 bits (286), Expect = 2.145e-25 Identity = 74/242 (30.58%), Postives = 126/242 (52.07%), Query Frame = 2 Query: 1817 TKVRFIEGKVKKDSIKISFFGTVSAGKSKVLNTIIGENLFLSAVADTTSCFVAVRKSDRGRHYLRVEGSETNFDSLTNLKNKVKELTTHLSENTTGRLDTTKTVQVFLNIENEIMKNNTEIFDCPGSNNKREVTECIMQQSLDSDIFIFVMTC--TLTNEEKDFFEYQSKLSSKPDIFVLVNKWDKSDQDKTAVTEKSRIKIKREIVNLLTKDGNFSSEEASKRIFFVSALEMFKCRIERKE 2536 +KVR I + + +K++FFG S GKS V+N ++ + + S + TT+CF+ V +D +L EGSE T V +L L ++ + +V ++ N + ++K++ + D PG + E+ I + LD+D+F+ V TL EK FF S+ S+P+IF+L N+WD S + + E R ++R L+ + G +A RIFFVSA E+ R+++ + Sbjct: 83 SKVRGISEVLARRHMKVAFFGRTSNGKSTVINAMLWDKVLPSGIGHTTNCFLRVGGTDGHEAFLLTEGSEEKKSVKT-----VNQLAHALHQDEQLHAGSMVSV-MWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKQFFHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHMERCTSFLVDELGVVDRAQAGDRIFFVSAKEVLSARVQKAQ 318 HSP 2 Score: 108.612 bits (270), Expect = 1.954e-23 Identity = 71/243 (29.22%), Postives = 125/243 (51.44%), Query Frame = 2 Query: 230 KINNIREILNKSEINVIFVGGVSTGKSKIINSILEEEILPSSIGVTNTKVVRLTGSNNGTS-CIKGCDKEFKDKEAMYEEVMNVSTDE-LDGNDNEALIEVVISNPKKPILNDKTFLIDTPGYNGNERAKELVMRTCQVSDIIVFVMT--YVFSDEEKEMFKLISEKTSKLNLFILVNKWDESDSDETFTVKMSKDMIEGRFVDWFKD-YNDTERNTAKSRIFFISAKEQMDSFMEAKEGINE 943 K+ I E+L + + V F G S GKS +IN++L +++LPS IG T +R+ G++ + + +E K + + + + DE L +++ V+ N K P+L D L+D+PG + + + C +D+ V V EK+ F +SE+ S+ N+FIL N+WD S S+ + ++ + +E R + D +R A RIFF+SAKE + + ++ +G+ E Sbjct: 84 KVRGISEVLARRHMKVAFFGRTSNGKSTVINAMLWDKVLPSGIGHTTNCFLRVGGTDGHEAFLLTEGSEEKKSVKTVNQLAHALHQDEQLHAG---SMVSVMWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKQFFHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHME-RCTSFLVDELGVVDRAQAGDRIFFVSAKEVLSARVQKAQGMPE 322
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Mouse
Match: Mfn2 (mitofusin 2 [Source:MGI Symbol;Acc:MGI:2442230]) HSP 1 Score: 114.775 bits (286), Expect = 2.145e-25 Identity = 74/242 (30.58%), Postives = 126/242 (52.07%), Query Frame = 2 Query: 1817 TKVRFIEGKVKKDSIKISFFGTVSAGKSKVLNTIIGENLFLSAVADTTSCFVAVRKSDRGRHYLRVEGSETNFDSLTNLKNKVKELTTHLSENTTGRLDTTKTVQVFLNIENEIMKNNTEIFDCPGSNNKREVTECIMQQSLDSDIFIFVMTC--TLTNEEKDFFEYQSKLSSKPDIFVLVNKWDKSDQDKTAVTEKSRIKIKREIVNLLTKDGNFSSEEASKRIFFVSALEMFKCRIERKE 2536 +KVR I + + +K++FFG S GKS V+N ++ + + S + TT+CF+ V +D +L EGSE T V +L L ++ + +V ++ N + ++K++ + D PG + E+ I + LD+D+F+ V TL EK FF S+ S+P+IF+L N+WD S + + E R ++R L+ + G +A RIFFVSA E+ R+++ + Sbjct: 83 SKVRGISEVLARRHMKVAFFGRTSNGKSTVINAMLWDKVLPSGIGHTTNCFLRVGGTDGHEAFLLTEGSEEKKSVKT-----VNQLAHALHQDEQLHAGSMVSV-MWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKQFFHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHMERCTSFLVDELGVVDRAQAGDRIFFVSAKEVLSARVQKAQ 318 HSP 2 Score: 108.612 bits (270), Expect = 1.954e-23 Identity = 71/243 (29.22%), Postives = 125/243 (51.44%), Query Frame = 2 Query: 230 KINNIREILNKSEINVIFVGGVSTGKSKIINSILEEEILPSSIGVTNTKVVRLTGSNNGTS-CIKGCDKEFKDKEAMYEEVMNVSTDE-LDGNDNEALIEVVISNPKKPILNDKTFLIDTPGYNGNERAKELVMRTCQVSDIIVFVMT--YVFSDEEKEMFKLISEKTSKLNLFILVNKWDESDSDETFTVKMSKDMIEGRFVDWFKD-YNDTERNTAKSRIFFISAKEQMDSFMEAKEGINE 943 K+ I E+L + + V F G S GKS +IN++L +++LPS IG T +R+ G++ + + +E K + + + + DE L +++ V+ N K P+L D L+D+PG + + + C +D+ V V EK+ F +SE+ S+ N+FIL N+WD S S+ + ++ + +E R + D +R A RIFF+SAKE + + ++ +G+ E Sbjct: 84 KVRGISEVLARRHMKVAFFGRTSNGKSTVINAMLWDKVLPSGIGHTTNCFLRVGGTDGHEAFLLTEGSEEKKSVKTVNQLAHALHQDEQLHAG---SMVSVMWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKQFFHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHME-RCTSFLVDELGVVDRAQAGDRIFFVSAKEVLSARVQKAQGMPE 322
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Mouse
Match: Mfn2 (mitofusin 2 [Source:MGI Symbol;Acc:MGI:2442230]) HSP 1 Score: 114.775 bits (286), Expect = 2.145e-25 Identity = 74/242 (30.58%), Postives = 126/242 (52.07%), Query Frame = 2 Query: 1817 TKVRFIEGKVKKDSIKISFFGTVSAGKSKVLNTIIGENLFLSAVADTTSCFVAVRKSDRGRHYLRVEGSETNFDSLTNLKNKVKELTTHLSENTTGRLDTTKTVQVFLNIENEIMKNNTEIFDCPGSNNKREVTECIMQQSLDSDIFIFVMTC--TLTNEEKDFFEYQSKLSSKPDIFVLVNKWDKSDQDKTAVTEKSRIKIKREIVNLLTKDGNFSSEEASKRIFFVSALEMFKCRIERKE 2536 +KVR I + + +K++FFG S GKS V+N ++ + + S + TT+CF+ V +D +L EGSE T V +L L ++ + +V ++ N + ++K++ + D PG + E+ I + LD+D+F+ V TL EK FF S+ S+P+IF+L N+WD S + + E R ++R L+ + G +A RIFFVSA E+ R+++ + Sbjct: 83 SKVRGISEVLARRHMKVAFFGRTSNGKSTVINAMLWDKVLPSGIGHTTNCFLRVGGTDGHEAFLLTEGSEEKKSVKT-----VNQLAHALHQDEQLHAGSMVSV-MWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKQFFHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHMERCTSFLVDELGVVDRAQAGDRIFFVSAKEVLSARVQKAQ 318 HSP 2 Score: 108.612 bits (270), Expect = 1.954e-23 Identity = 71/243 (29.22%), Postives = 125/243 (51.44%), Query Frame = 2 Query: 230 KINNIREILNKSEINVIFVGGVSTGKSKIINSILEEEILPSSIGVTNTKVVRLTGSNNGTS-CIKGCDKEFKDKEAMYEEVMNVSTDE-LDGNDNEALIEVVISNPKKPILNDKTFLIDTPGYNGNERAKELVMRTCQVSDIIVFVMT--YVFSDEEKEMFKLISEKTSKLNLFILVNKWDESDSDETFTVKMSKDMIEGRFVDWFKD-YNDTERNTAKSRIFFISAKEQMDSFMEAKEGINE 943 K+ I E+L + + V F G S GKS +IN++L +++LPS IG T +R+ G++ + + +E K + + + + DE L +++ V+ N K P+L D L+D+PG + + + C +D+ V V EK+ F +SE+ S+ N+FIL N+WD S S+ + ++ + +E R + D +R A RIFF+SAKE + + ++ +G+ E Sbjct: 84 KVRGISEVLARRHMKVAFFGRTSNGKSTVINAMLWDKVLPSGIGHTTNCFLRVGGTDGHEAFLLTEGSEEKKSVKTVNQLAHALHQDEQLHAG---SMVSVMWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKQFFHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHME-RCTSFLVDELGVVDRAQAGDRIFFVSAKEVLSARVQKAQGMPE 322
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Mouse
Match: Mfn1 (mitofusin 1 [Source:MGI Symbol;Acc:MGI:1914664]) HSP 1 Score: 108.227 bits (269), Expect = 2.777e-23 Identity = 72/239 (30.13%), Postives = 127/239 (53.14%), Query Frame = 2 Query: 1820 KVRFIEGKVKKDSIKISFFGTVSAGKSKVLNTIIGENLFLSAVADTTSCFVAVRKSDRGRHYLRVEGSE--TNFDSLTNLKNKVKELTTHLSENTTGRLDTTKTVQVFL-NIENEIMKNNTEIFDCPGSNNKREVTECIMQQSLDSDIFIFVMT--CTLTNEEKDFFEYQSKLSSKPDIFVLVNKWDKSDQDKTAVTEKSRIKIKREIVNLLTKDGNFSSEEASKRIFFVSALEMFKCR 2521 K+ I + + +K++FFG S+GKS V+N ++ + + S + TT+CF++V +D + YL EGS+ + ++ L + + H+ ++ L V VF + +++++ + D PG++ E+ I + LD+D+F+ V TL N EK FF ++ SKP+IF+L N+WD S + + + R ++R + L+ + S EA RIFFVSA E+ R Sbjct: 63 KLAVIGEVLSRRHMKVAFFGRTSSGKSSVINAMLWDKVLPSGIGHTTNCFLSVEGTDGDKAYLMTEGSDEKKSVKTVNQLAHAL-----HMDKD----LKAGCLVHVFWPKAKCALLRDDLVLVDSPGTDVTTELDIWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMEDVRRQHMERCLHFLVEELKVVSPSEARNRIFFVSAKEVLNSR 292 HSP 2 Score: 98.5969 bits (244), Expect = 2.558e-20 Identity = 77/291 (26.46%), Postives = 139/291 (47.77%), Query Frame = 2 Query: 143 TFDEEKYDKIFTLNESCESLLSRIRARQLKINNIREILNKSEINVIFVGGVSTGKSKIINSILEEEILPSSIGVTNTKVVRLTGSNNGTSCI--KGCDKEFKDKEA-MYEEVMNVSTDELDGNDNEALIEVVISNPKKPILNDKTFLIDTPGYNGNERAKELVMRTCQVSDIIVFVMT--YVFSDEEKEMFKLISEKTSKLNLFILVNKWDESDSDETFTVKMSKDMIEGRFVDWFKDYNDTERNTAKSRIFFISAKEQMDSFMEAKEGINE----------YRKEEFKRF 970 T+ + D+I + E L I+ + K+ I E+L++ + V F G S+GKS +IN++L +++LPS IG T + + G++ + + +G D++ K +++ D G L+ V K +L D L+D+PG + + + C +D+ V V + EK F ++E+ SK N+FIL N+WD S S+ + + + +E ++ + A++RIFF+SAKE ++S +G+ E R +EF+ F Sbjct: 39 TYRNPELDRI-----ASEDDLVEIQGYRNKLAVIGEVLSRRHMKVAFFGRTSSGKSSVINAMLWDKVLPSGIGHTTNCFLSVEGTDGDKAYLMTEGSDEKKSVKTVNQLAHALHMDKDLKAG----CLVHVFWPKAKCALLRDDLVLVDSPGTDVTTELDIWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMEDVRRQHMERCLHFLVEELKVVSPSEARNRIFFVSAKEVLNSRKHKAQGMPEGGGALAEGFQARLQEFQNF 320
BLAST of Dynamin-type G domain-containing protein vs. UniProt/SwissProt
Match: sp|Q7YU24|MARF_DROME (Transmembrane GTPase Marf OS=Drosophila melanogaster OX=7227 GN=Marf PE=1 SV=1) HSP 1 Score: 128.257 bits (321), Expect = 1.119e-28 Identity = 86/262 (32.82%), Postives = 140/262 (53.44%), Query Frame = 2 Query: 1820 KVRFIEGKVKKDSIKISFFGTVSAGKSKVLNTIIGENLFLSAVADTTSCFVAVRKSDRGRHYLRVEGSETNFDSLTNLKNKVKELTTHLSENTTGRLDTTKTVQVFLNIEN-EIMKNNTEIFDCPGSNNKREVTECIMQQSLDSDIFIFVMTC--TLTNEEKDFFEYQSKLSSKPDIFVLVNKWDKSDQDKTAVTEKSRIKIKREIVNLLTKDGNFSSE-EASKRIFFVSALEMFKCRIERKEIFGNQRTRRAI----EMRY 2581 KV I +++D +K++FFG S GKS V+N ++ E + S + TT+CF V S+ G YL EGSE + + +K+L L + +L + V++F E +++++ D PG + + + I L++D+F+ V+ T+T EK FF S+ SKP+IF+L N+WD S ++ E + + ++ LTK+ S+E EA++R+FFVSA E + RIE E GN AI ++RY Sbjct: 125 KVAAIREVLQRDHMKVAFFGRTSNGKSSVINAMLREKILPSGIGHTTNCFCQVEGSNGGEAYLMTEGSEEKLNVVN-----IKQLANALCQE---KLCESSLVRIFWPRERCSLLRDDVVFVDSPGVDVSANLDDWIDNHCLNADVFVLVLNAESTMTRAEKQFFHTVSQKLSKPNIFILNNRWDAS-ANEPECQESVKSQHTERCIDFLTKELKVSNEKEAAERVFFVSARETLQARIE--EAKGNPPHMGAIAEGFQIRY 375 HSP 2 Score: 104.76 bits (260), Expect = 2.421e-21 Identity = 69/238 (28.99%), Postives = 118/238 (49.58%), Query Frame = 2 Query: 230 KINNIREILNKSEINVIFVGGVSTGKSKIINSILEEEILPSSIGVTNTKVVRLTGSNNGTSCIKGCDKEFKDKEAMYEEVMNVSTDELDGNDNEALIEVVISNPKKPILNDKTFLIDTPGYNGNERAKELVMRTCQVSDIIVFVMTY--VFSDEEKEMFKLISEKTSKLNLFILVNKWDESDSDETFTVKMSKDMIEGRFVDWF-KDYNDTERNTAKSRIFFISAKEQMDSFMEAKEG 934 K+ IRE+L + + V F G S GKS +IN++L E+ILPS IG T ++ GSN G + + E K +++ N E +L+ + + +L D +D+PG + + + + C +D+ V V+ + EK+ F +S+K SK N+FIL N+WD S ++ + E R +D+ K+ + A R+FF+SA+E + + +E +G Sbjct: 125 KVAAIREVLQRDHMKVAFFGRTSNGKSSVINAMLREKILPSGIGHTTNCFCQVEGSNGGEAYLMTEGSEEKLNVVNIKQLANALCQEKLCES--SLVRIFWPRERCSLLRDDVVFVDSPGVDVSANLDDWIDNHCLNADVFVLVLNAESTMTRAEKQFFHTVSQKLSKPNIFILNNRWDASANEPECQESVKSQHTE-RCIDFLTKELKVSNEKEAAERVFFVSARETLQARIEEAKG 359
BLAST of Dynamin-type G domain-containing protein vs. UniProt/SwissProt
Match: sp|O95140|MFN2_HUMAN (Mitofusin-2 OS=Homo sapiens OX=9606 GN=MFN2 PE=1 SV=3) HSP 1 Score: 117.472 bits (293), Expect = 2.202e-25 Identity = 75/242 (30.99%), Postives = 127/242 (52.48%), Query Frame = 2 Query: 1817 TKVRFIEGKVKKDSIKISFFGTVSAGKSKVLNTIIGENLFLSAVADTTSCFVAVRKSDRGRHYLRVEGSETNFDSLTNLKNKVKELTTHLSENTTGRLDTTKTVQVFLNIENEIMKNNTEIFDCPGSNNKREVTECIMQQSLDSDIFIFVMTC--TLTNEEKDFFEYQSKLSSKPDIFVLVNKWDKSDQDKTAVTEKSRIKIKREIVNLLTKDGNFSSEEASKRIFFVSALEMFKCRIERKE 2536 +KVR I + + +K++FFG S GKS V+N ++ + + S + TT+CF+ V +D +L EGSE + T V +L L ++ + +V ++ N + ++K++ + D PG + E+ I + LD+D+F+ V TL EK FF S+ S+P+IF+L N+WD S + + E R ++R L+ + G +A RIFFVSA E+ RI++ + Sbjct: 83 SKVRGISEVLARRHMKVAFFGRTSNGKSTVINAMLWDKVLPSGIGHTTNCFLRVEGTDGHEAFLLTEGSEEKRSAKT-----VNQLAHALHQDKQLHAGSLVSV-MWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKHFFHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHMERCTSFLVDELGVVDRSQAGDRIFFVSAKEVLNARIQKAQ 318 HSP 2 Score: 109.768 bits (273), Expect = 7.099e-23 Identity = 69/241 (28.63%), Postives = 123/241 (51.04%), Query Frame = 2 Query: 230 KINNIREILNKSEINVIFVGGVSTGKSKIINSILEEEILPSSIGVTNTKVVRLTGSNNGTSCIKGCDKEFKDKEAMYEEVMNVSTDELDGNDNEALIEVVISNPKKPILNDKTFLIDTPGYNGNERAKELVMRTCQVSDIIVFVMT--YVFSDEEKEMFKLISEKTSKLNLFILVNKWDESDSDETFTVKMSKDMIEGRFVDWFKD-YNDTERNTAKSRIFFISAKEQMDSFMEAKEGINE 943 K+ I E+L + + V F G S GKS +IN++L +++LPS IG T +R+ G++ + + E K ++ + + + +L+ V+ N K P+L D L+D+PG + + + C +D+ V V EK F +SE+ S+ N+FIL N+WD S S+ + ++ + +E R + D +R+ A RIFF+SAKE +++ ++ +G+ E Sbjct: 84 KVRGISEVLARRHMKVAFFGRTSNGKSTVINAMLWDKVLPSGIGHTTNCFLRVEGTDGHEAFLLTEGSEEKRSAKTVNQLAHALHQDKQLHAG-SLVSVMWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKHFFHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHME-RCTSFLVDELGVVDRSQAGDRIFFVSAKEVLNARIQKAQGMPE 322
BLAST of Dynamin-type G domain-containing protein vs. UniProt/SwissProt
Match: sp|Q80U63|MFN2_MOUSE (Mitofusin-2 OS=Mus musculus OX=10090 GN=Mfn2 PE=1 SV=3) HSP 1 Score: 114.775 bits (286), Expect = 1.501e-24 Identity = 74/242 (30.58%), Postives = 126/242 (52.07%), Query Frame = 2 Query: 1817 TKVRFIEGKVKKDSIKISFFGTVSAGKSKVLNTIIGENLFLSAVADTTSCFVAVRKSDRGRHYLRVEGSETNFDSLTNLKNKVKELTTHLSENTTGRLDTTKTVQVFLNIENEIMKNNTEIFDCPGSNNKREVTECIMQQSLDSDIFIFVMTC--TLTNEEKDFFEYQSKLSSKPDIFVLVNKWDKSDQDKTAVTEKSRIKIKREIVNLLTKDGNFSSEEASKRIFFVSALEMFKCRIERKE 2536 +KVR I + + +K++FFG S GKS V+N ++ + + S + TT+CF+ V +D +L EGSE T V +L L ++ + +V ++ N + ++K++ + D PG + E+ I + LD+D+F+ V TL EK FF S+ S+P+IF+L N+WD S + + E R ++R L+ + G +A RIFFVSA E+ R+++ + Sbjct: 83 SKVRGISEVLARRHMKVAFFGRTSNGKSTVINAMLWDKVLPSGIGHTTNCFLRVGGTDGHEAFLLTEGSEEKKSVKT-----VNQLAHALHQDEQLHAGSMVSV-MWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKQFFHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHMERCTSFLVDELGVVDRAQAGDRIFFVSAKEVLSARVQKAQ 318 HSP 2 Score: 108.612 bits (270), Expect = 1.367e-22 Identity = 71/243 (29.22%), Postives = 125/243 (51.44%), Query Frame = 2 Query: 230 KINNIREILNKSEINVIFVGGVSTGKSKIINSILEEEILPSSIGVTNTKVVRLTGSNNGTS-CIKGCDKEFKDKEAMYEEVMNVSTDE-LDGNDNEALIEVVISNPKKPILNDKTFLIDTPGYNGNERAKELVMRTCQVSDIIVFVMT--YVFSDEEKEMFKLISEKTSKLNLFILVNKWDESDSDETFTVKMSKDMIEGRFVDWFKD-YNDTERNTAKSRIFFISAKEQMDSFMEAKEGINE 943 K+ I E+L + + V F G S GKS +IN++L +++LPS IG T +R+ G++ + + +E K + + + + DE L +++ V+ N K P+L D L+D+PG + + + C +D+ V V EK+ F +SE+ S+ N+FIL N+WD S S+ + ++ + +E R + D +R A RIFF+SAKE + + ++ +G+ E Sbjct: 84 KVRGISEVLARRHMKVAFFGRTSNGKSTVINAMLWDKVLPSGIGHTTNCFLRVGGTDGHEAFLLTEGSEEKKSVKTVNQLAHALHQDEQLHAG---SMVSVMWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKQFFHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHME-RCTSFLVDELGVVDRAQAGDRIFFVSAKEVLSARVQKAQGMPE 322
BLAST of Dynamin-type G domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8R500|MFN2_RAT (Mitofusin-2 OS=Rattus norvegicus OX=10116 GN=Mfn2 PE=1 SV=1) HSP 1 Score: 114.775 bits (286), Expect = 1.679e-24 Identity = 74/242 (30.58%), Postives = 125/242 (51.65%), Query Frame = 2 Query: 1817 TKVRFIEGKVKKDSIKISFFGTVSAGKSKVLNTIIGENLFLSAVADTTSCFVAVRKSDRGRHYLRVEGSETNFDSLTNLKNKVKELTTHLSENTTGRLDTTKTVQVFLNIENEIMKNNTEIFDCPGSNNKREVTECIMQQSLDSDIFIFVMTC--TLTNEEKDFFEYQSKLSSKPDIFVLVNKWDKSDQDKTAVTEKSRIKIKREIVNLLTKDGNFSSEEASKRIFFVSALEMFKCRIERKE 2536 +KVR I + + +K++FFG S GKS V+N ++ + + S + TT+CF+ V +D +L EGSE T V +L L ++ + +V ++ N + ++K+ + D PG + E+ I + LD+D+F+ V TL EK FF S+ S+P+IF+L N+WD S + + E R ++R L+ + G +A RIFFVSA E+ R+++ + Sbjct: 83 SKVRGISEVLARRHMKVAFFGRTSNGKSTVINAMLWDKVLPSGIGHTTNCFLRVGGTDGHEAFLLTEGSEEKKSVKT-----VNQLAHALHQDEQLHAGSLVSV-MWPNSKCPLLKDGLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKQFFHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHMERCTSFLVDELGVVDRAQAGDRIFFVSAKEVLSARVQKAQ 318 HSP 2 Score: 109.383 bits (272), Expect = 7.285e-23 Identity = 72/243 (29.63%), Postives = 125/243 (51.44%), Query Frame = 2 Query: 230 KINNIREILNKSEINVIFVGGVSTGKSKIINSILEEEILPSSIGVTNTKVVRLTGSNNGTS-CIKGCDKEFKDKEAMYEEVMNVSTDE-LDGNDNEALIEVVISNPKKPILNDKTFLIDTPGYNGNERAKELVMRTCQVSDIIVFVMT--YVFSDEEKEMFKLISEKTSKLNLFILVNKWDESDSDETFTVKMSKDMIEGRFVDWFKD-YNDTERNTAKSRIFFISAKEQMDSFMEAKEGINE 943 K+ I E+L + + V F G S GKS +IN++L +++LPS IG T +R+ G++ + + +E K + + + + DE L +L+ V+ N K P+L D L+D+PG + + + C +D+ V V EK+ F +SE+ S+ N+FIL N+WD S S+ + ++ + +E R + D +R A RIFF+SAKE + + ++ +G+ E Sbjct: 84 KVRGISEVLARRHMKVAFFGRTSNGKSTVINAMLWDKVLPSGIGHTTNCFLRVGGTDGHEAFLLTEGSEEKKSVKTVNQLAHALHQDEQLHAG---SLVSVMWPNSKCPLLKDGLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKQFFHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHME-RCTSFLVDELGVVDRAQAGDRIFFVSAKEVLSARVQKAQGMPE 322
BLAST of Dynamin-type G domain-containing protein vs. UniProt/SwissProt
Match: sp|O18412|FZO_DROME (Transmembrane GTPase fzo OS=Drosophila melanogaster OX=7227 GN=fzo PE=1 SV=2) HSP 1 Score: 109.768 bits (273), Expect = 6.335e-23 Identity = 69/241 (28.63%), Postives = 130/241 (53.94%), Query Frame = 2 Query: 1817 TKVRFIEGKVKKDSIKISFFGTVSAGKSKVLNTIIGENLFLSAVADTTSCFVAVRKSDRGR-HYLRVEGSETNFDSLTNLKNKVKELTTHLSENTTGRLDTTKTVQVFLNIEN-EIMKNNTEIFDCPGSNNKREVTECIMQQSLDSDIFIFVMTC--TLTNEEKDFFEYQSKLSSKPDIFVLVNKWDKSDQDKTAVTEKSRIKIKREIVNLLTKD-GNFS-SEEASKRIFFVSALEMFKCR 2521 ++V I + +D +K++FFG S GKS V+N ++ E + SA+ TTSCF V+ + +++VE + + + + L+ S ++ G L + +QV + I+ + + D PG + ++ +C+ +D+D+FI V+ T++ E+ FF+ + S+P++F+L N+WDK+ + + +K + + VNLL + G +S ++EA +RI+ VSALE R Sbjct: 73 SRVEAIAKVLSRDRMKVAFFGRTSNGKSAVINALLHEKILPSAMGHTTSCFCQVQANGSNETEHVKVEQEDEHME--------LSALSQLASAHSPGALKPSTLLQVNMAKNRCSILDYDVVLMDTPGVDVTAQLDDCLDSYCMDADVFILVLNAESTVSRVERQFFKDVASKLSRPNLFILNNRWDKASSLEPEMEQKVKDQHMERCVNLLVDELGVYSTAQEAWERIYHVSALEALHIR 305 HSP 2 Score: 95.1301 bits (235), Expect = 2.260e-18 Identity = 73/276 (26.45%), Postives = 137/276 (49.64%), Query Frame = 2 Query: 200 LLSRIRARQLKINNIREILNKSEINVIFVGGVSTGKSKIINSILEEEILPSSIGVTNTKVVRLTGSNNGTSCIKGCDKEFKDKEAMYEEVMNVSTDELDGN-DNEALIEVVISNPKKPILNDKTFLIDTPGYNGNERAKELVMRTCQVSDIIVFVMTY--VFSDEEKEMFKLISEKTSKLNLFILVNKWDESDSDETFTVKMSKDMIEGRFVDWFKD----YNDTERNTAKSRIFFISAKEQM---DSFMEAKEGINEYRKEEFKRFITELNKSLS 997 +L + A ++ I ++L++ + V F G S GKS +IN++L E+ILPS++G T + ++ NG++ + E +D+ + +++ G L++V ++ + IL+ L+DTPG + + + + C +D+ + V+ S E++ FK ++ K S+ NLFIL N+WD++ S E + KD R V+ D Y+ + A RI+ +SA E + + + G + R +EF RF + + L+ Sbjct: 64 MLEHLCAFSSRVEAIAKVLSRDRMKVAFFGRTSNGKSAVINALLHEKILPSAMGHTTSCFCQVQA--NGSNETEHVKVEQEDEHMELSALSQLASAHSPGALKPSTLLQVNMAKNRCSILDYDVVLMDTPGVDVTAQLDDCLDSYCMDADVFILVLNAESTVSRVERQFFKDVASKLSRPNLFILNNRWDKASSLEPEMEQKVKDQHMERCVNLLVDELGVYSTAQE--AWERIYHVSALEALHIRNGQITNPSGQTQQRYQEFLRFENDFSNCLA 335
BLAST of Dynamin-type G domain-containing protein vs. TrEMBL
Match: B4R5L5 (GD16797 OS=Drosophila simulans OX=7240 GN=Dsim\GD16797 PE=3 SV=1) HSP 1 Score: 128.257 bits (321), Expect = 4.202e-28 Identity = 86/262 (32.82%), Postives = 140/262 (53.44%), Query Frame = 2 Query: 1820 KVRFIEGKVKKDSIKISFFGTVSAGKSKVLNTIIGENLFLSAVADTTSCFVAVRKSDRGRHYLRVEGSETNFDSLTNLKNKVKELTTHLSENTTGRLDTTKTVQVFLNIEN-EIMKNNTEIFDCPGSNNKREVTECIMQQSLDSDIFIFVMTC--TLTNEEKDFFEYQSKLSSKPDIFVLVNKWDKSDQDKTAVTEKSRIKIKREIVNLLTKDGNFSSE-EASKRIFFVSALEMFKCRIERKEIFGNQRTRRAI----EMRY 2581 KV I +++D +K++FFG S GKS V+N ++ E + S + TT+CF V S+ G YL EGSE + + +K+L L + +L + V++F E +++++ D PG + + + I L++D+F+ V+ T+T EK FF S+ SKP+IF+L N+WD S ++ E + + ++ LTK+ S+E EA++R+FFVSA E + RIE E GN AI ++RY Sbjct: 81 KVAAIREVLQRDHMKVAFFGRTSNGKSSVINAMLREKILPSGIGHTTNCFCQVEGSNGGEAYLMTEGSEEKLNVVN-----IKQLANALCQE---KLCESSLVRIFWPRERCSLLRDDVVFVDSPGVDVSANLDDWIDNHCLNADVFVLVLNAESTMTRAEKQFFHTVSQKLSKPNIFILNNRWDAS-ANEPECQESVKSQHTERCIDFLTKELKVSNEKEAAERVFFVSARETLQARIE--EAKGNPPHMGAIAEGFQIRY 331 HSP 2 Score: 105.916 bits (263), Expect = 1.436e-20 Identity = 70/238 (29.41%), Postives = 119/238 (50.00%), Query Frame = 2 Query: 230 KINNIREILNKSEINVIFVGGVSTGKSKIINSILEEEILPSSIGVTNTKVVRLTGSNNGTSCIKGCDKEFKDKEAMYEEVMNVSTDELDGNDNEALIEVVISNPKKPILNDKTFLIDTPGYNGNERAKELVMRTCQVSDIIVFVMTY--VFSDEEKEMFKLISEKTSKLNLFILVNKWDESDSDETFTVKMSKDMIEGRFVDWF-KDYNDTERNTAKSRIFFISAKEQMDSFMEAKEG 934 K+ IRE+L + + V F G S GKS +IN++L E+ILPS IG T ++ GSN G + + E K +++ N E +L+ + + +L D +D+PG + + + + C +D+ V V+ + EK+ F +S+K SK N+FIL N+WD S ++E + K R +D+ K+ + A R+FF+SA+E + + +E +G Sbjct: 81 KVAAIREVLQRDHMKVAFFGRTSNGKSSVINAMLREKILPSGIGHTTNCFCQVEGSNGGEAYLMTEGSEEKLNVVNIKQLANALCQEKLCES--SLVRIFWPRERCSLLRDDVVFVDSPGVDVSANLDDWIDNHCLNADVFVLVLNAESTMTRAEKQFFHTVSQKLSKPNIFILNNRWDAS-ANEPECQESVKSQHTERCIDFLTKELKVSNEKEAAERVFFVSARETLQARIEEAKG 315
BLAST of Dynamin-type G domain-containing protein vs. TrEMBL
Match: A0A0R1E9R8 (Uncharacterized protein, isoform B OS=Drosophila yakuba OX=7245 GN=Dyak\GE16751 PE=3 SV=1) HSP 1 Score: 129.413 bits (324), Expect = 1.649e-26 Identity = 87/265 (32.83%), Postives = 145/265 (54.72%), Query Frame = 2 Query: 1820 KVRFIEGKVKKDSIKISFFGTVSAGKSKVLNTIIGENLFLSAVADTTSCFVAVRKSDRGRHYLRVEGSETNFDSLTNLKNKVKELTTHLSENTTGRLDTTKTVQVFLNIEN-EIMKNNTEIFDCPGSNNKREVTECIMQQSLDSDIFIFVMTC--TLTNEEKDFFEYQSKLSSKPDIFVLVNKWDKS-DQDKTAVTEKSRIKIKR--EIVNLLTKDGNFSSE-EASKRIFFVSALEMFKCRIERKEIFGNQRTRRAI----EMRY 2581 KV I +++D +K++FFG S GKS V+N ++ E + S + TT+CF V S+ G YL EGSE + + +K+L L + +L + V++F E +++++ D PG + + + I L++D+F+ V+ T+T EK FF S+ SKP+IF+L N+WD S ++ + +E +++K + ++ LTK+ S+E EA++R+FFVSA E + RIE E GN AI ++RY Sbjct: 125 KVAAIREVLQRDHMKVAFFGRTSNGKSSVINAMLREKILPSGIGHTTNCFCQVEGSNGGEAYLMTEGSEEKLNVVN-----IKQLANALCQE---KLCESSLVRIFWPRERCSLLRDDVVFVDSPGVDVSANLDDWIDNHCLNADVFVLVLNAESTMTRAEKQFFHTVSQKLSKPNIFILNNRWDASANEPECQESELAKVKSQHTERCIDFLTKELKVSNEKEAAERVFFVSARETLQARIE--EAKGNPPHMGAIAEGFQIRY 379 HSP 2 Score: 105.145 bits (261), Expect = 5.081e-19 Identity = 71/242 (29.34%), Postives = 120/242 (49.59%), Query Frame = 2 Query: 230 KINNIREILNKSEINVIFVGGVSTGKSKIINSILEEEILPSSIGVTNTKVVRLTGSNNGTSCIKGCDKEFKDKEAMYEEVMNVSTDELDGNDNEALIEVVISNPKKPILNDKTFLIDTPGYNGNERAKELVMRTCQVSDIIVFVMTY--VFSDEEKEMFKLISEKTSKLNLFILVNKWD----ESDSDETFTVKMSKDMIEGRFVDWF-KDYNDTERNTAKSRIFFISAKEQMDSFMEAKEG 934 K+ IRE+L + + V F G S GKS +IN++L E+ILPS IG T ++ GSN G + + E K +++ N E +L+ + + +L D +D+PG + + + + C +D+ V V+ + EK+ F +S+K SK N+FIL N+WD E + E+ K+ E R +D+ K+ + A R+FF+SA+E + + +E +G Sbjct: 125 KVAAIREVLQRDHMKVAFFGRTSNGKSSVINAMLREKILPSGIGHTTNCFCQVEGSNGGEAYLMTEGSEEKLNVVNIKQLANALCQEKLCES--SLVRIFWPRERCSLLRDDVVFVDSPGVDVSANLDDWIDNHCLNADVFVLVLNAESTMTRAEKQFFHTVSQKLSKPNIFILNNRWDASANEPECQESELAKVKSQHTE-RCIDFLTKELKVSNEKEAAERVFFVSARETLQARIEEAKG 363
BLAST of Dynamin-type G domain-containing protein vs. TrEMBL
Match: A0A0Q5T5B2 (Uncharacterized protein, isoform C OS=Drosophila erecta OX=7220 GN=Dere\GG19591 PE=3 SV=1) HSP 1 Score: 129.028 bits (323), Expect = 1.917e-26 Identity = 87/265 (32.83%), Postives = 145/265 (54.72%), Query Frame = 2 Query: 1820 KVRFIEGKVKKDSIKISFFGTVSAGKSKVLNTIIGENLFLSAVADTTSCFVAVRKSDRGRHYLRVEGSETNFDSLTNLKNKVKELTTHLSENTTGRLDTTKTVQVFLNIEN-EIMKNNTEIFDCPGSNNKREVTECIMQQSLDSDIFIFVMTC--TLTNEEKDFFEYQSKLSSKPDIFVLVNKWDKS-DQDKTAVTEKSRIKIKR--EIVNLLTKDGNFSSE-EASKRIFFVSALEMFKCRIERKEIFGNQRTRRAI----EMRY 2581 KV I +++D +K++FFG S GKS V+N ++ E + S + TT+CF V S+ G YL EGSE + + +K+L L + +L + V++F E +++++ D PG + + + I L++D+F+ V+ T+T EK FF S+ SKP+IF+L N+WD S ++ + +E +++K + ++ LTK+ S+E EA++R+FFVSA E + RIE E GN AI ++RY Sbjct: 123 KVAAIREVLQRDHMKVAFFGRTSNGKSSVINAMLREKILPSGIGHTTNCFCQVEGSNGGEAYLMTEGSEEKLNVVN-----IKQLANALCQE---KLCESSLVRIFWPRERCSLLRDDVVFVDSPGVDVSANLDDWIDNHCLNADVFVLVLNAESTMTRAEKQFFHTVSQKLSKPNIFILNNRWDASANEPECQESELAKVKSQHTERCIDFLTKELKVSNEKEAAERVFFVSARETLQARIE--EAKGNPPHMGAIAEGFQIRY 377 HSP 2 Score: 105.145 bits (261), Expect = 6.012e-19 Identity = 71/242 (29.34%), Postives = 120/242 (49.59%), Query Frame = 2 Query: 230 KINNIREILNKSEINVIFVGGVSTGKSKIINSILEEEILPSSIGVTNTKVVRLTGSNNGTSCIKGCDKEFKDKEAMYEEVMNVSTDELDGNDNEALIEVVISNPKKPILNDKTFLIDTPGYNGNERAKELVMRTCQVSDIIVFVMTY--VFSDEEKEMFKLISEKTSKLNLFILVNKWD----ESDSDETFTVKMSKDMIEGRFVDWF-KDYNDTERNTAKSRIFFISAKEQMDSFMEAKEG 934 K+ IRE+L + + V F G S GKS +IN++L E+ILPS IG T ++ GSN G + + E K +++ N E +L+ + + +L D +D+PG + + + + C +D+ V V+ + EK+ F +S+K SK N+FIL N+WD E + E+ K+ E R +D+ K+ + A R+FF+SA+E + + +E +G Sbjct: 123 KVAAIREVLQRDHMKVAFFGRTSNGKSSVINAMLREKILPSGIGHTTNCFCQVEGSNGGEAYLMTEGSEEKLNVVNIKQLANALCQEKLCES--SLVRIFWPRERCSLLRDDVVFVDSPGVDVSANLDDWIDNHCLNADVFVLVLNAESTMTRAEKQFFHTVSQKLSKPNIFILNNRWDASANEPECQESELAKVKSQHTE-RCIDFLTKELKVSNEKEAAERVFFVSARETLQARIEEAKG 361
BLAST of Dynamin-type G domain-containing protein vs. TrEMBL
Match: A0A1I8P3X4 (Dynamin-type G domain-containing protein OS=Stomoxys calcitrans OX=35570 GN=106083566 PE=3 SV=1) HSP 1 Score: 129.028 bits (323), Expect = 1.918e-26 Identity = 89/257 (34.63%), Postives = 139/257 (54.09%), Query Frame = 2 Query: 1820 KVRFIEGKVKKDSIKISFFGTVSAGKSKVLNTIIGENLFLSAVADTTSCFVAVRKSDRGRHYLRVEGSETNFDSLTNLKNKVKELTTHLSENTTGRLDTTKTVQVFLNIENEIMKNNTEIF-DCPGSNNKREVTECIMQQSLDSDIFIFVMTC--TLTNEEKDFFEYQSKLSSKPDIFVLVNKWDKS---DQDKTAVTEKSRIKIKREIVNLLTKDGNFSSE-EASKRIFFVSALEMFKCRIERKEIFGNQRTRRAI 2569 KV I + +D +K++FFG S GKS V+N ++ E + S + TT+CF V SD YL EGS D N+ N +K+L L + +L + V++F E ++ + +F D PG + + + I L++D+F+ V+ T+T EK FF S+ SKP+IF+L N+WD S + + + EK + + ++ LTK+ SSE EA++R+FFVSA E + RIE E GN ++ AI Sbjct: 98 KVAGIREVLARDHMKVAFFGRTSNGKSSVINAMLREKILPSGIGHTTNCFCQVEGSDSSEAYLVKEGS----DEKLNVVN-IKQLANALCQE---KLSESSLVRIFWPRERCMLLRDDVVFVDSPGVDVSANLDDWIDNHCLNADVFVLVLNAESTMTRAEKQFFHTVSQKLSKPNIFILNNRWDASANEPESQESELEKVKSQHTERCIDFLTKELKVSSEKEAAERVFFVSAREALQARIE--EAKGNSPSQGAI 344 HSP 2 Score: 102.834 bits (255), Expect = 2.722e-18 Identity = 72/251 (28.69%), Postives = 128/251 (51.00%), Query Frame = 2 Query: 227 LKINNIREILNKSEINVIFVGGVSTGKSKIINSILEEEILPSSIGVTNTKVVRLTGSNNGTSCI--KGCDKEF------KDKEAMYEEVMNVSTDELDGNDNEALIEVVISNPKKPILNDKTFLIDTPGYNGNERAKELVMRTCQVSDIIVFVMTY--VFSDEEKEMFKLISEKTSKLNLFILVNKWD----ESDSDETFTVKMSKDMIEGRFVDWF-KDYNDTERNTAKSRIFFISAKEQMDSFMEAKEG 934 LK+ IRE+L + + V F G S GKS +IN++L E+ILPS IG T ++ GS++ + + +G D++ + A+ +E ++ S+ L+ + + +L D +D+PG + + + + C +D+ V V+ + EK+ F +S+K SK N+FIL N+WD E +S E+ K+ E R +D+ K+ + A R+FF+SA+E + + +E +G Sbjct: 97 LKVAGIREVLARDHMKVAFFGRTSNGKSSVINAMLREKILPSGIGHTTNCFCQVEGSDSSEAYLVKEGSDEKLNVVNIKQLANALCQEKLSESS----------LVRIFWPRERCMLLRDDVVFVDSPGVDVSANLDDWIDNHCLNADVFVLVLNAESTMTRAEKQFFHTVSQKLSKPNIFILNNRWDASANEPESQESELEKVKSQHTE-RCIDFLTKELKVSSEKEAAERVFFVSAREALQARIEEAKG 336
BLAST of Dynamin-type G domain-containing protein vs. TrEMBL
Match: A0A1I8P3Z4 (Dynamin-type G domain-containing protein OS=Stomoxys calcitrans OX=35570 GN=106083566 PE=3 SV=1) HSP 1 Score: 129.028 bits (323), Expect = 1.981e-26 Identity = 89/257 (34.63%), Postives = 139/257 (54.09%), Query Frame = 2 Query: 1820 KVRFIEGKVKKDSIKISFFGTVSAGKSKVLNTIIGENLFLSAVADTTSCFVAVRKSDRGRHYLRVEGSETNFDSLTNLKNKVKELTTHLSENTTGRLDTTKTVQVFLNIENEIMKNNTEIF-DCPGSNNKREVTECIMQQSLDSDIFIFVMTC--TLTNEEKDFFEYQSKLSSKPDIFVLVNKWDKS---DQDKTAVTEKSRIKIKREIVNLLTKDGNFSSE-EASKRIFFVSALEMFKCRIERKEIFGNQRTRRAI 2569 KV I + +D +K++FFG S GKS V+N ++ E + S + TT+CF V SD YL EGS D N+ N +K+L L + +L + V++F E ++ + +F D PG + + + I L++D+F+ V+ T+T EK FF S+ SKP+IF+L N+WD S + + + EK + + ++ LTK+ SSE EA++R+FFVSA E + RIE E GN ++ AI Sbjct: 108 KVAGIREVLARDHMKVAFFGRTSNGKSSVINAMLREKILPSGIGHTTNCFCQVEGSDSSEAYLVKEGS----DEKLNVVN-IKQLANALCQE---KLSESSLVRIFWPRERCMLLRDDVVFVDSPGVDVSANLDDWIDNHCLNADVFVLVLNAESTMTRAEKQFFHTVSQKLSKPNIFILNNRWDASANEPESQESELEKVKSQHTERCIDFLTKELKVSSEKEAAERVFFVSAREALQARIE--EAKGNSPSQGAI 354 HSP 2 Score: 102.834 bits (255), Expect = 2.816e-18 Identity = 72/251 (28.69%), Postives = 128/251 (51.00%), Query Frame = 2 Query: 227 LKINNIREILNKSEINVIFVGGVSTGKSKIINSILEEEILPSSIGVTNTKVVRLTGSNNGTSCI--KGCDKEF------KDKEAMYEEVMNVSTDELDGNDNEALIEVVISNPKKPILNDKTFLIDTPGYNGNERAKELVMRTCQVSDIIVFVMTY--VFSDEEKEMFKLISEKTSKLNLFILVNKWD----ESDSDETFTVKMSKDMIEGRFVDWF-KDYNDTERNTAKSRIFFISAKEQMDSFMEAKEG 934 LK+ IRE+L + + V F G S GKS +IN++L E+ILPS IG T ++ GS++ + + +G D++ + A+ +E ++ S+ L+ + + +L D +D+PG + + + + C +D+ V V+ + EK+ F +S+K SK N+FIL N+WD E +S E+ K+ E R +D+ K+ + A R+FF+SA+E + + +E +G Sbjct: 107 LKVAGIREVLARDHMKVAFFGRTSNGKSSVINAMLREKILPSGIGHTTNCFCQVEGSDSSEAYLVKEGSDEKLNVVNIKQLANALCQEKLSESS----------LVRIFWPRERCMLLRDDVVFVDSPGVDVSANLDDWIDNHCLNADVFVLVLNAESTMTRAEKQFFHTVSQKLSKPNIFILNNRWDASANEPESQESELEKVKSQHTE-RCIDFLTKELKVSSEKEAAERVFFVSAREALQARIEEAKG 346
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000043809.1 (mitofusin-1-like [Source:NCBI gene;Acc:103034819]) HSP 1 Score: 115.931 bits (289), Expect = 8.525e-26 Identity = 89/304 (29.28%), Postives = 156/304 (51.32%), Query Frame = 2 Query: 1820 KVRFIEGKVKKDSIKISFFGTVSAGKSKVLNTIIGENLFLSAVADTTSCFVAVRKSDRGRHYLRVEGSETNFDSLTNLKNKVKELTTHLSENTTGRLDTTKTVQVFL-NIENEIMKNNTEIFDCPGSNNKREVTECIMQQSLDSDIFIFVMT--CTLTNEEKDFFEYQSKLSSKPDIFVLVNKWDKSDQDKTAVTEKSRIKIKREIVNLLTKDGNFSSEEASKRIFFVSALEMFKCRIERKEIFGNQRTRRAIEMRYXXXXXXXXXXXR----YIDNPEI-NKLERHDREVRETTRNLESIIES 2707 K+ I + + +K++FFG S GKS V+N ++ E + S + TT+CF++V +D + +L E SE S+ + L H+ N LD+ V+VF + +++++ + D PG++ E+ I + LD+D+F+ V TL N EK FF S+ SKP+IF+L N+WD S+ + + + + R + L+ + S ++A RIFFVSA E RI R + G T A+ +++ L +S R +I + + K E+H + T +L++I+++ Sbjct: 64 KLEAIWEVLARRQMKVAFFGRTSNGKSTVINAMLRERVLPSGIGHTTNCFISVEGTDGDQAFLTTENSEER-KSIKTVNQLAHAL--HMDRN----LDSGCLVRVFWPKTKCALLRDDLVLMDSPGTDVTSELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVSERISKPNIFILNNRWDASETEPEYLDGVRKQHMDRCVSFLVDELKVVSPDQAPNRIFFVSAKEALSARIHRAQ--GMPETGAALADGFQDRLQEFQSFERTFEEFISHSSVKTKFEQHTIRAWQITESLKTIMDA 358 HSP 2 Score: 102.834 bits (255), Expect = 8.883e-22 Identity = 73/261 (27.97%), Postives = 127/261 (48.66%), Query Frame = 2 Query: 230 KINNIREILNKSEINVIFVGGVSTGKSKIINSILEEEILPSSIGVTNTKVVRLTGSNNGTSCIKGCDKEFKDKEAMYEEVMNVSTDELDGN-DNEALIEVVISNPKKPILNDKTFLIDTPGYNGNERAKELVMRTCQVSDIIVFVMT--YVFSDEEKEMFKLISEKTSKLNLFILVNKWDESDSDETFTVKMSKDMIEGRFVDWFKD-YNDTERNTAKSRIFFISAKEQMDSFMEAKEGINEY----------RKEEFKRF 970 K+ I E+L + ++ V F G S GKS +IN++L E +LPS IG T + + G++ + + + E + ++ + +D N D+ L+ V K +L D L+D+PG + + + C +D+ V V + EK F +SE+ SK N+FIL N+WD S+++ + + K ++ R V + D + A +RIFF+SAKE + + + +G+ E R +EF+ F Sbjct: 64 KLEAIWEVLARRQMKVAFFGRTSNGKSTVINAMLRERVLPSGIGHTTNCFISVEGTDGDQAFLTTENSEERKSIKTVNQLAHAL--HMDRNLDSGCLVRVFWPKTKCALLRDDLVLMDSPGTDVTSELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVSERISKPNIFILNNRWDASETEPEYLDGVRKQHMD-RCVSFLVDELKVVSPDQAPNRIFFVSAKEALSARIHRAQGMPETGAALADGFQDRLQEFQSF 321
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Cavefish
Match: mfn1b (mitofusin-1 [Source:NCBI gene;Acc:103030239]) HSP 1 Score: 115.546 bits (288), Expect = 1.140e-25 Identity = 81/264 (30.68%), Postives = 139/264 (52.65%), Query Frame = 2 Query: 1757 SDSPILCTIENFVKKYEIIETKVRFIEGKVKKDSIKISFFGTVSAGKSKVLNTIIGENLFLSAVADTTSCFVAVRKSDRGRHYLRVEGSETNFDSLTNLKNKVKELTTHLSENTTGRLDTTKTVQVFL-NIENEIMKNNTEIFDCPGSNNKREVTECIMQQSLDSDIFIFVMT--CTLTNEEKDFFEYQSKLSSKPDIFVLVNKWDKSDQDKTAVTEKSRIKIKREIVNLLTKDGN-FSSEEASKRIFFVSALEMFKCRIERKE 2536 +DS L IE++ +K +I+ + + +K++FFG S GKS V+N ++ + + S + TT+CF++V +D + YL+ EGSE S+ + L H+ E+ LD V+VF + +++++ + D PG++ ++ I + LD+D+F+ V TL N EK FF ++ SKP+IF+L N+WD S + + + + R VN L ++ EEA IFFVSA E+ R++R + Sbjct: 50 ADSTQLQEIESYTEKLAVIKEVL-------ARRHMKVAFFGRTSNGKSTVINAMLRDRVLPSGIGHTTNCFLSVEGTDEDKAYLKTEGSEEE-KSIKTVNQLAHAL--HMDES----LDAGCLVKVFWPKTKCALLRDDLVLVDSPGTDVTTQLDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMDDVRKQHTDR-CVNFLVEELKVVDREEAPNHIFFVSAKEVLNSRMQRAQ 298 HSP 2 Score: 105.145 bits (261), Expect = 1.774e-22 Identity = 74/252 (29.37%), Postives = 130/252 (51.59%), Query Frame = 2 Query: 203 LSRIRARQLKINNIREILNKSEINVIFVGGVSTGKSKIINSILEEEILPSSIGVTNTKVVRLTGSNNGTSCIK--GCDKEFKDKEAMYEEVMNVSTDELDGNDNEALIEVVISNPKKPILNDKTFLIDTPGYNGNERAKELVMRTCQVSDIIVFVMT--YVFSDEEKEMFKLISEKTSKLNLFILVNKWDESDSDETFTVKMSKDMIEGRFVDWF-KDYNDTERNTAKSRIFFISAKEQMDSFMEAKEGINE 943 L I + K+ I+E+L + + V F G S GKS +IN++L + +LPS IG T + + G++ + +K G ++E K + + + + DE D L++V K +L D L+D+PG + + + + C +D+ V V + EK F ++E+ SK N+FIL N+WD S S+ + + K + R V++ ++ +R A + IFF+SAKE ++S M+ +G+ E Sbjct: 55 LQEIESYTEKLAVIKEVLARRHMKVAFFGRTSNGKSTVINAMLRDRVLPSGIGHTTNCFLSVEGTDEDKAYLKTEGSEEE-KSIKTVNQLAHALHMDE--SLDAGCLVKVFWPKTKCALLRDDLVLVDSPGTDVTTQLDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMDDVRKQHTD-RCVNFLVEELKVVDREEAPNHIFFVSAKEVLNSRMQRAQGMPE 302
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Cavefish
Match: mfn1b (mitofusin-1 [Source:NCBI gene;Acc:103030239]) HSP 1 Score: 115.161 bits (287), Expect = 1.303e-25 Identity = 81/264 (30.68%), Postives = 139/264 (52.65%), Query Frame = 2 Query: 1757 SDSPILCTIENFVKKYEIIETKVRFIEGKVKKDSIKISFFGTVSAGKSKVLNTIIGENLFLSAVADTTSCFVAVRKSDRGRHYLRVEGSETNFDSLTNLKNKVKELTTHLSENTTGRLDTTKTVQVFL-NIENEIMKNNTEIFDCPGSNNKREVTECIMQQSLDSDIFIFVMT--CTLTNEEKDFFEYQSKLSSKPDIFVLVNKWDKSDQDKTAVTEKSRIKIKREIVNLLTKDGN-FSSEEASKRIFFVSALEMFKCRIERKE 2536 +DS L IE++ +K +I+ + + +K++FFG S GKS V+N ++ + + S + TT+CF++V +D + YL+ EGSE S+ + L H+ E+ LD V+VF + +++++ + D PG++ ++ I + LD+D+F+ V TL N EK FF ++ SKP+IF+L N+WD S + + + + R VN L ++ EEA IFFVSA E+ R++R + Sbjct: 50 ADSTQLQEIESYTEKLAVIKEVL-------ARRHMKVAFFGRTSNGKSTVINAMLRDRVLPSGIGHTTNCFLSVEGTDEDKAYLKTEGSEEE-KSIKTVNQLAHAL--HMDES----LDAGCLVKVFWPKTKCALLRDDLVLVDSPGTDVTTQLDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMDDVRKQHTDR-CVNFLVEELKVVDREEAPNHIFFVSAKEVLNSRMQRAQ 298 HSP 2 Score: 105.145 bits (261), Expect = 2.090e-22 Identity = 74/252 (29.37%), Postives = 130/252 (51.59%), Query Frame = 2 Query: 203 LSRIRARQLKINNIREILNKSEINVIFVGGVSTGKSKIINSILEEEILPSSIGVTNTKVVRLTGSNNGTSCIK--GCDKEFKDKEAMYEEVMNVSTDELDGNDNEALIEVVISNPKKPILNDKTFLIDTPGYNGNERAKELVMRTCQVSDIIVFVMT--YVFSDEEKEMFKLISEKTSKLNLFILVNKWDESDSDETFTVKMSKDMIEGRFVDWF-KDYNDTERNTAKSRIFFISAKEQMDSFMEAKEGINE 943 L I + K+ I+E+L + + V F G S GKS +IN++L + +LPS IG T + + G++ + +K G ++E K + + + + DE D L++V K +L D L+D+PG + + + + C +D+ V V + EK F ++E+ SK N+FIL N+WD S S+ + + K + R V++ ++ +R A + IFF+SAKE ++S M+ +G+ E Sbjct: 55 LQEIESYTEKLAVIKEVLARRHMKVAFFGRTSNGKSTVINAMLRDRVLPSGIGHTTNCFLSVEGTDEDKAYLKTEGSEEE-KSIKTVNQLAHALHMDE--SLDAGCLVKVFWPKTKCALLRDDLVLVDSPGTDVTTQLDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMDDVRKQHTD-RCVNFLVEELKVVDREEAPNHIFFVSAKEVLNSRMQRAQGMPE 302
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Cavefish
Match: mfn2 (mitofusin 2 [Source:ZFIN;Acc:ZDB-GENE-081105-44]) HSP 1 Score: 107.071 bits (266), Expect = 4.572e-23 Identity = 77/274 (28.10%), Postives = 136/274 (49.64%), Query Frame = 2 Query: 143 TFDEEKYDKIFTLNESCESLLSRIRARQLKINNIREILNKSEINVIFVGGVSTGKSKIINSILEEEILPSSIGVTNTKVVRLTGSN-NGTSCIKGCDKEFKDKEAMYEEVMNVSTDE-LDGNDNEALIEVVISNPKKPILNDKTFLIDTPGYNGNERAKELVMRTCQVSDIIVFVMT--YVFSDEEKEMFKLISEKTSKLNLFILVNKWDESDSDETFTVKMSK---DMIEGRFVDWFKDYNDTERNTAKSRIFFISAKEQMDSFMEAKEGINE 943 T+ E+ D + T E ++ +R K+ I E+L++ + V+F G S GKS +IN++L +++LPS IG T +R+ G++ N + +E K+ + + + + DE LD +L+ V+ K +L D L+D+PG + + + C +D+ V V EK F ++E+ S N+FIL N+WD S S+ + ++ + D VD + +R A RIFF+SAKE + + ++ +G+ E Sbjct: 60 TYSNEELDPVTT-----EEQVAEVRGYLSKVAGIGEVLSRRHMKVVFFGRTSNGKSSVINAMLWDKVLPSGIGHTTNCFLRVEGTDGNEAFLLTEGSEERKNVKTVNQLAHALHQDEDLDAG---SLVCVMWPKAKCALLRDDLVLVDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKSFFHKVNERLSSPNIFILNNRWDASASEPEYMEEVRRQHMDRCSSFLVD---ELGVVDRAQASDRIFFVSAKEVLQARVQKAQGMPE 322 HSP 2 Score: 107.071 bits (266), Expect = 4.732e-23 Identity = 75/243 (30.86%), Postives = 125/243 (51.44%), Query Frame = 2 Query: 1817 TKVRFIEGKVKKDSIKISFFGTVSAGKSKVLNTIIGENLFLSAVADTTSCFVAVRKSDRGRHYLRVEGSETNFDSLTNLKNKVKELTTHLSENTTGRLDTTKTVQV-FLNIENEIMKNNTEIFDCPGSNNKREVTECIMQQSLDSDIFIFVMTC--TLTNEEKDFFEYQSKLSSKPDIFVLVNKWDKSDQDKTAVTEKSRIKIKREIVNLLTKDGNFSSEEASKRIFFVSALEMFKCRIERKE 2536 +KV I + + +K+ FFG S GKS V+N ++ + + S + TT+CF+ V +D +L EGSE N+K V +L L ++ LD V V + + +++++ + D PG + E+ I + LD+D+F+ V TL EK FF ++ S P+IF+L N+WD S + + E R + R L+ + G +AS RIFFVSA E+ + R+++ + Sbjct: 83 SKVAGIGEVLSRRHMKVVFFGRTSNGKSSVINAMLWDKVLPSGIGHTTNCFLRVEGTDGNEAFLLTEGSEER----KNVKT-VNQLAHALHQDED--LDAGSLVCVMWPKAKCALLRDDLVLVDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKSFFHKVNERLSSPNIFILNNRWDASASEPEYMEEVRRQHMDRCSSFLVDELGVVDRAQASDRIFFVSAKEVLQARVQKAQ 318
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Nematostella
Match: EDO42379 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S1L1]) HSP 1 Score: 99.3673 bits (246), Expect = 4.828e-21 Identity = 96/391 (24.55%), Postives = 174/391 (44.50%), Query Frame = 2 Query: 56 NKIQEKSSNLCKFVESIHGFEKELRETCRTFDEEKYDKIFTLNESCESLLSRIRARQL-------KINNIREILNKSEINVIFVGGVSTGKSKIINSILEEEILPSSIGVTNTKVVRLTGSNNGTSCI--------KGCDKEFKDKEAMYEEVMNVSTDELDGNDNEALIEVVISNPKKPILNDKTFLIDTPGYNGNERAKELVMRTCQVSDIIVFVMTY--VFSDEEKEMFKLISEKTSKLNLFILVNKWDESDSDETF-TVKMSKDMIEGRFVDWF-KDYNDTERNTAKSRIFFISAKEQMDSFMEAKEGINE-----------YRKEEFKRFITELNKSLSDPKFCKCLKHEQDITNMENDMKADIDITINDLEEIIHSRSKSISELR 1138 N + E SS L FV++ + + E + DE ++ E E S I+ ++ +I E++ + ++ V F G S GKS ++N++L++ ILP IG T + + GS++ I + + A++EE + D+ +L++V + +L++ L+D+PG + + + + C +D+ V V EK F +++K SK N+FIL N+WD S + +++ K R VD+ K+ ++ A+ R+FF+SAKE + S M+ +G+ E RK EF+ F + KF +C+ T E+ I I +N ++ I+ + E R Sbjct: 20 NGVGEHSSPLHNFVKAKKKINETVSEIGKYLDEA--NRFICGCEIAEDYKSNIKGFACDVAGFLGQVASITEVIARDQMKVAFFGRTSNGKSTVVNAMLQDRILPMGIGHTTNCFLSVNGSDSADPYILIPESDERRNVKTLGQIAHALFEEKL----------DHSSLVQVYWPKSRCKMLSEDVVLVDSPGIDVSPDLDLWIDKHCLDADVFVLVCNAESTLMVTEKNFFHKVNQKLSKPNIFILNNRWDASAGEPDVEMMELVKKQHLQRNVDFLSKELKCVDKKQAEDRVFFVSAKETLMSRMQKHQGMPEEGGAIHVDGFHGRKLEFENF---------EHKFEECISKSAIQTKFESHAGTGIGI-VNAVQNILEQIAGCAYEHR 388 HSP 2 Score: 96.6709 bits (239), Expect = 2.780e-20 Identity = 69/239 (28.87%), Postives = 125/239 (52.30%), Query Frame = 2 Query: 1844 VKKDSIKISFFGTVSAGKSKVLNTIIGENLFLSAVADTTSCFVAVRKSDRGRHYLRVEGSETNFDSLTNLKNKVKELTTHLSENTTGRLDTTKTVQVFLNIEN-EIMKNNTEIFDCPGSNNKREVTECIMQQSLDSDIFIFVMTC--TLTNEEKDFFEYQSKLSSKPDIFVLVNKWDKS----DQDKTAVTEKSRIKIKREIVNLLTKDGN-FSSEEASKRIFFVSALEMFKCRIERKE 2536 + +D +K++FFG S GKS V+N ++ + + + TT+CF++V SD Y+ + S D N+K + ++ L E +LD + VQV+ +++ + + D PG + ++ I + LD+D+F+ V TL EK+FF ++ SKP+IF+L N+WD S D + + +K ++ V+ L+K+ ++A R+FFVSA E R+++ + Sbjct: 91 IARDQMKVAFFGRTSNGKSTVVNAMLQDRILPMGIGHTTNCFLSVNGSDSADPYILIPES----DERRNVKT-LGQIAHALFEE---KLDHSSLVQVYWPKSRCKMLSEDVVLVDSPGIDVSPDLDLWIDKHCLDADVFVLVCNAESTLMVTEKNFFHKVNQKLSKPNIFILNNRWDASAGEPDVEMMELVKKQHLQRN---VDFLSKELKCVDKKQAEDRVFFVSAKETLMSRMQKHQ 318
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000009003.2 (pep primary_assembly:ASM223467v1:17:11595384:11602171:-1 gene:ENSORLG00000007178.2 transcript:ENSORLT00000009003.2 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 114.005 bits (284), Expect = 8.040e-27 Identity = 79/243 (32.51%), Postives = 127/243 (52.26%), Query Frame = 2 Query: 1817 TKVRFIEGKVKKDSIKISFFGTVSAGKSKVLNTIIGENLFLSAVADTTSCFVAVRKSDRGRHYLRVEGSETNFDSLTNLKNKVKELTTHLSENTTGRLDTTKTVQVFLNIEN-EIMKNNTEIFDCPGSNNKREVTECIMQQSLDSDIFIFV--MTCTLTNEEKDFFEYQSKLSSKPDIFVLVNKWDKSDQDKTAVTEKSRIKIKREIVNLLTKDGNFSSEEASKRIFFVSALEMFKCRIERKE 2536 TK+ I + + +K++FFG S GKS V+N ++ + + S + TT+CF++V +D YL E SE T V +L L + T LD++ V+VF +++N+ + D PG++ E+ I + LD+D+F+ V TL N EK FF S+ SKP+IF+L N+WD S + + E + + R + L + G EA RIFF+SA E+ R++R + Sbjct: 61 TKLYTIRDVLLRRHMKVAFFGRTSNGKSTVINAMLRDRVLPSGIGHTTNCFLSVEGTDGDEAYLTSEASEERRSIST-----VNQLAHALHMDPT--LDSSCLVKVFWPKSRCALLRNDLVLMDSPGTDVTLELDSWIDKFCLDADVFVLVGNAESTLMNTEKLFFHKVSERISKPNIFILHNRWDASVTEPDYIQEVRKQHLDRCVGFLAEELGVVGPNEAPGRIFFISAKEVLSSRMQRAQ 296 HSP 2 Score: 96.6709 bits (239), Expect = 5.641e-21 Identity = 76/267 (28.46%), Postives = 128/267 (47.94%), Query Frame = 2 Query: 230 KINNIREILNKSEINVIFVGGVSTGKSKIINSILEEEILPSSIGVTNTKVVRLTGSNNGTSCIKGCDKEFKDKEAMYEEVMNVSTDELDGN-------DNEALIEVVISNPKKPILNDKTFLIDTPGYNGNERAKELVMRTCQVSDIIVFV--MTYVFSDEEKEMFKLISEKTSKLNLFILVNKWDESDSDETFTVKMSKDMIEGRFVDWF-KDYNDTERNTAKSRIFFISAKEQMDSFMEAKEGINEY----------RKEEFKRF 970 K+ IR++L + + V F G S GKS +IN++L + +LPS IG T + + G++ D+ + EA E + ++L D+ L++V + +L + L+D+PG + + + C +D+ V V + EK F +SE+ SK N+FIL N+WD S ++ + ++ K ++ R V + ++ N A RIFFISAKE + S M+ +G+ E R EF+RF Sbjct: 62 KLYTIRDVLLRRHMKVAFFGRTSNGKSTVINAMLRDRVLPSGIGHTTNCFLSVEGTDG--------DEAYLTSEASEERRSISTVNQLAHALHMDPTLDSSCLVKVFWPKSRCALLRNDLVLMDSPGTDVTLELDSWIDKFCLDADVFVLVGNAESTLMNTEKLFFHKVSERISKPNIFILHNRWDASVTEPDYIQEVRKQHLD-RCVGFLAEELGVVGPNEAPGRIFFISAKEVLSSRMQRAQGMPETGGALAEGFHERLTEFQRF 319
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Medaka
Match: mfn1b (mitofusin 1 [Source:NCBI gene;Acc:101158009]) HSP 1 Score: 114.005 bits (284), Expect = 3.049e-25 Identity = 75/245 (30.61%), Postives = 133/245 (54.29%), Query Frame = 2 Query: 1820 KVRFIEGKVKKDSIKISFFGTVSAGKSKVLNTIIGENLFLSAVADTTSCFVAVRKSDRGRHYLRVEGS--ETNFDSLTNLKNKVKELTTHLSENTTGRLDTTKTVQVFL-NIENEIMKNNTEIFDCPGSNNKREVTECIMQQSLDSDIFIFVMT--CTLTNEEKDFFEYQSKLSSKPDIFVLVNKWDKSDQDKTAVTEKSRIKIKREIVNLLTKDGN-FSSEEASKRIFFVSALEMFKCRIERKE 2536 K+ I+ + + +K++FFG S GKS V+N ++ + + S + TT+CF++V +D R YL+ EGS E + ++ + + + H+ E+ LD V+VF + +++++ + D PG++ ++ I + LD+D+F+ V TL N EK FF ++ SKP+IF+L N+WD S ++ E R + VN L ++ E+A RIFF+SA E+ R++R + Sbjct: 75 KLAVIKEVLARRHMKVAFFGRTSNGKSTVINAMLRDRVLPSGIGHTTNCFLSVEGTDDDRSYLKTEGSDEEKSIKTVNQMAHAL-----HMDES----LDAGCLVRVFWPKTKCALLRDDLVLVDSPGTDVTTQLDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDAS-ANEPEYMEDVRKQHTDRCVNFLVEELKVVDREQAPNRIFFISAKEVLNSRMQRAQ 309 HSP 2 Score: 112.464 bits (280), Expect = 1.142e-24 Identity = 91/308 (29.55%), Postives = 152/308 (49.35%), Query Frame = 2 Query: 35 DTYLETLNKIQEKSSNLCKFVESIHGFEKELRETCRTFDEEKYDKIFTLNESCESLLSRIRARQLKINNIREILNKSEINVIFVGGVSTGKSKIINSILEEEILPSSIGVTNTKVVRLTGSNNGTSCIK--GCDKEFKDKEAMYEEVMNVSTDELDGNDNEALIEVVISNPKKPILNDKTFLIDTPGYNGNERAKELVMRTCQVSDIIVFVMT--YVFSDEEKEMFKLISEKTSKLNLFILVNKWDESDSDETFTVKMSKDMIEGRFVDWF-KDYNDTERNTAKSRIFFISAKEQMDSFMEAKEGINE 943 D + + LN ++E S +FVE I G E T D++ S I+A K+ I+E+L + + V F G S GKS +IN++L + +LPS IG T + + G+++ S +K G D+E K + + + + DE D L+ V K +L D L+D+PG + + + + C +D+ V V + EK F ++E+ SK N+FIL N+WD S ++ + + K + R V++ ++ +R A +RIFFISAKE ++S M+ +G+ E Sbjct: 32 DVFEQLLNYVKETS----EFVEDISG--NTALENVATPDQK----------------SEIQAYADKLAVIKEVLARRHMKVAFFGRTSNGKSTVINAMLRDRVLPSGIGHTTNCFLSVEGTDDDRSYLKTEGSDEE-KSIKTVNQMAHALHMDE--SLDAGCLVRVFWPKTKCALLRDDLVLVDSPGTDVTTQLDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASANEPEYMEDVRKQHTD-RCVNFLVEELKVVDREQAPNRIFFISAKEVLNSRMQRAQGMPE 313
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Medaka
Match: mfn1b (mitofusin 1 [Source:NCBI gene;Acc:101158009]) HSP 1 Score: 114.005 bits (284), Expect = 3.232e-25 Identity = 75/245 (30.61%), Postives = 133/245 (54.29%), Query Frame = 2 Query: 1820 KVRFIEGKVKKDSIKISFFGTVSAGKSKVLNTIIGENLFLSAVADTTSCFVAVRKSDRGRHYLRVEGS--ETNFDSLTNLKNKVKELTTHLSENTTGRLDTTKTVQVFL-NIENEIMKNNTEIFDCPGSNNKREVTECIMQQSLDSDIFIFVMT--CTLTNEEKDFFEYQSKLSSKPDIFVLVNKWDKSDQDKTAVTEKSRIKIKREIVNLLTKDGN-FSSEEASKRIFFVSALEMFKCRIERKE 2536 K+ I+ + + +K++FFG S GKS V+N ++ + + S + TT+CF++V +D R YL+ EGS E + ++ + + + H+ E+ LD V+VF + +++++ + D PG++ ++ I + LD+D+F+ V TL N EK FF ++ SKP+IF+L N+WD S ++ E R + VN L ++ E+A RIFF+SA E+ R++R + Sbjct: 75 KLAVIKEVLARRHMKVAFFGRTSNGKSTVINAMLRDRVLPSGIGHTTNCFLSVEGTDDDRSYLKTEGSDEEKSIKTVNQMAHAL-----HMDES----LDAGCLVRVFWPKTKCALLRDDLVLVDSPGTDVTTQLDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDAS-ANEPEYMEDVRKQHTDRCVNFLVEELKVVDREQAPNRIFFISAKEVLNSRMQRAQ 309 HSP 2 Score: 111.694 bits (278), Expect = 1.738e-24 Identity = 78/251 (31.08%), Postives = 132/251 (52.59%), Query Frame = 2 Query: 206 SRIRARQLKINNIREILNKSEINVIFVGGVSTGKSKIINSILEEEILPSSIGVTNTKVVRLTGSNNGTSCIK--GCDKEFKDKEAMYEEVMNVSTDELDGNDNEALIEVVISNPKKPILNDKTFLIDTPGYNGNERAKELVMRTCQVSDIIVFVMT--YVFSDEEKEMFKLISEKTSKLNLFILVNKWDESDSDETFTVKMSKDMIEGRFVDWF-KDYNDTERNTAKSRIFFISAKEQMDSFMEAKEGINE 943 S I+A K+ I+E+L + + V F G S GKS +IN++L + +LPS IG T + + G+++ S +K G D+E K + + + + DE D L+ V K +L D L+D+PG + + + + C +D+ V V + EK F ++E+ SK N+FIL N+WD S ++ + + K + R V++ ++ +R A +RIFFISAKE ++S M+ +G+ E Sbjct: 67 SEIQAYADKLAVIKEVLARRHMKVAFFGRTSNGKSTVINAMLRDRVLPSGIGHTTNCFLSVEGTDDDRSYLKTEGSDEE-KSIKTVNQMAHALHMDE--SLDAGCLVRVFWPKTKCALLRDDLVLVDSPGTDVTTQLDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASANEPEYMEDVRKQHTD-RCVNFLVEELKVVDREQAPNRIFFISAKEVLNSRMQRAQGMPE 313
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Medaka
Match: mfn2 (mitofusin 2 [Source:NCBI gene;Acc:101170481]) HSP 1 Score: 107.842 bits (268), Expect = 2.491e-23 Identity = 78/254 (30.71%), Postives = 130/254 (51.18%), Query Frame = 2 Query: 1778 TIENFVKKYEIIETKVRFIEGKVKKDSIKISFFGTVSAGKSKVLNTIIGENLFLSAVADTTSCFVAVRKSDRGRHYLRVEGSETNFDSLTNLKNKVKELTTHLSENTTGRLDTTKTVQV-FLNIENEIMKNNTEIFDCPGSNNKREVTECIMQQSLDSDIFIFVMTC--TLTNEEKDFFEYQSKLSSKPDIFVLVNKWDKSDQDKTAVTEKSRIKIKREIVNLLTKDGNFSSEEASKRIFFVSALEMFKCRIER 2530 T E V++ +KV I + + +K+ FFG S GKS V+N ++ + + S + TT+CF+ V +D +L EGSE ++K V +L L ++ LD V V + ++ +++++ + D PG + E+ I + LD+D+F+ V TL EK FF ++ S P+IF+L N+WD S + + E R + R L+ + G +AS RIFFVSA E+ + R++R Sbjct: 70 TAEEQVQEVRGFLSKVAGIGEVLARRHMKVVFFGRTSNGKSTVINAMLCDKVLPSGIGHTTNCFLRVEGTDGSEGFLLTEGSEEK----KSIKT-VNQLAHALHQDQD--LDAGSLVCVMWPKVKCALLRDDLVLVDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKSFFHKVNERLSSPNIFILNNRWDASASEPEYMDEVRRQHMDRCSNFLVEELGVVDRAQASDRIFFVSAKEVLQARMQR 316 HSP 2 Score: 100.908 bits (250), Expect = 4.378e-21 Identity = 68/254 (26.77%), Postives = 123/254 (48.43%), Query Frame = 2 Query: 188 SCESLLSRIRARQLKINNIREILNKSEINVIFVGGVSTGKSKIINSILEEEILPSSIGVTNTKVVRLTGSNNGTSCIKGCDKEFKDKEAMYEEVMNVSTDELDGNDNEALIEVVISNPKKPILNDKTFLIDTPGYNGNERAKELVMRTCQVSDIIVFVMT--YVFSDEEKEMFKLISEKTSKLNLFILVNKWDESDSDETFTVKMSKDMIEGRFVDWFKDYNDTERNTAKSRIFFISAKEQMDSFMEAKEGINE 943 + E + +R K+ I E+L + + V+F G S GKS +IN++L +++LPS IG T +R+ G++ + E K ++ + + D D +L+ V+ K +L D L+D+PG + + + C +D+ V V EK F ++E+ S N+FIL N+WD S S+ + ++ + ++ ++ +R A RIFF+SAKE + + M+ +G+ E Sbjct: 70 TAEEQVQEVRGFLSKVAGIGEVLARRHMKVVFFGRTSNGKSTVINAMLCDKVLPSGIGHTTNCFLRVEGTDGSEGFLLTEGSEEKKSIKTVNQLAHALHQDQD-LDAGSLVCVMWPKVKCALLRDDLVLVDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKSFFHKVNERLSSPNIFILNNRWDASASEPEYMDEVRRQHMDRCSNFLVEELGVVDRAQASDRIFFVSAKEVLQARMQRVQGMPE 322
BLAST of Dynamin-type G domain-containing protein vs. Planmine SMEST
Match: SMESG000014754.1 (SMESG000014754.1) HSP 1 Score: 762.296 bits (1967), Expect = 0.000e+0 Identity = 378/378 (100.00%), Postives = 378/378 (100.00%), Query Frame = 2 Query: 26 MPEDTYLETLNKIQEKSSNLCKFVESIHGFEKELRETCRTFDEEKYDKIFTLNESCESLLSRIRARQLKINNIREILNKSEINVIFVGGVSTGKSKIINSILEEEILPSSIGVTNTKVVRLTGSNNGTSCIKGCDKEFKDKEAMYEEVMNVSTDELDGNDNEALIEVVISNPKKPILNDKTFLIDTPGYNGNERAKELVMRTCQVSDIIVFVMTYVFSDEEKEMFKLISEKTSKLNLFILVNKWDESDSDETFTVKMSKDMIEGRFVDWFKDYNDTERNTAKSRIFFISAKEQMDSFMEAKEGINEYRKEEFKRFITELNKSLSDPKFCKCLKHEQDITNMENDMKADIDITINDLEEIIHSRSKSISELRNIKSSLK 1159 MPEDTYLETLNKIQEKSSNLCKFVESIHGFEKELRETCRTFDEEKYDKIFTLNESCESLLSRIRARQLKINNIREILNKSEINVIFVGGVSTGKSKIINSILEEEILPSSIGVTNTKVVRLTGSNNGTSCIKGCDKEFKDKEAMYEEVMNVSTDELDGNDNEALIEVVISNPKKPILNDKTFLIDTPGYNGNERAKELVMRTCQVSDIIVFVMTYVFSDEEKEMFKLISEKTSKLNLFILVNKWDESDSDETFTVKMSKDMIEGRFVDWFKDYNDTERNTAKSRIFFISAKEQMDSFMEAKEGINEYRKEEFKRFITELNKSLSDPKFCKCLKHEQDITNMENDMKADIDITINDLEEIIHSRSKSISELRNIKSSLK Sbjct: 1 MPEDTYLETLNKIQEKSSNLCKFVESIHGFEKELRETCRTFDEEKYDKIFTLNESCESLLSRIRARQLKINNIREILNKSEINVIFVGGVSTGKSKIINSILEEEILPSSIGVTNTKVVRLTGSNNGTSCIKGCDKEFKDKEAMYEEVMNVSTDELDGNDNEALIEVVISNPKKPILNDKTFLIDTPGYNGNERAKELVMRTCQVSDIIVFVMTYVFSDEEKEMFKLISEKTSKLNLFILVNKWDESDSDETFTVKMSKDMIEGRFVDWFKDYNDTERNTAKSRIFFISAKEQMDSFMEAKEGINEYRKEEFKRFITELNKSLSDPKFCKCLKHEQDITNMENDMKADIDITINDLEEIIHSRSKSISELRNIKSSLK 378 HSP 2 Score: 108.612 bits (270), Expect = 9.677e-25 Identity = 76/254 (29.92%), Postives = 129/254 (50.79%), Query Frame = 2 Query: 1778 TIENFVKKYEIIETKVRFIEGKVKKDSIKISFFGTVSAGKSKVLNTIIGENLFLSAVADTTSCFVAVRKSDRGRHYLRVEGSETNFDSLTNLKNKVKELTTHLSENTTGRLDTTKTVQVFL-NIENEIMKNNTEIFDCPGSNNKREVTECIMQQSLDSDIFIFVMTCTLTNEEKDFFEYQSKLSSKPDIFVLVNKWDKSDQDKTAVTEKSRIKIKREIVNLLTKDGNFSSEEASKRIFFVSALEMFKCRIERKE 2536 + E+ + + + K+ I + K I + F G VS GKSK++N+I+ E + S++ T + V + S+ G ++ G + F K + E ++S + D ++V + N + I+ + T + D PG N E +M+ SDI +FVMT ++EEK+ F+ S+ +SK ++F+LVNKWD+SD D+T + S+ I+ V+ + A RIFF+SA E +E KE Sbjct: 55 SCESLLSRIRARQLKINNIREILNKSEINVIFVGGVSTGKSKIINSILEEEILPSSIGVTNTKVVRLTGSNNGTSCIK--GCDKEFKD----KEAMYEEVMNVSTDELDGNDNEALIEVVISNPKKPILNDKTFLIDTPGYNGNERAKELVMRTCQVSDIIVFVMTYVFSDEEKEMFKLISEKTSKLNLFILVNKWDESDSDETFTVKMSKDMIEGRFVDWFKDYNDTERNTAKSRIFFISAKEQMDSFMEAKE 302
BLAST of Dynamin-type G domain-containing protein vs. Planmine SMEST
Match: SMESG000014754.1 (SMESG000014754.1) HSP 1 Score: 762.296 bits (1967), Expect = 0.000e+0 Identity = 378/378 (100.00%), Postives = 378/378 (100.00%), Query Frame = 2 Query: 26 MPEDTYLETLNKIQEKSSNLCKFVESIHGFEKELRETCRTFDEEKYDKIFTLNESCESLLSRIRARQLKINNIREILNKSEINVIFVGGVSTGKSKIINSILEEEILPSSIGVTNTKVVRLTGSNNGTSCIKGCDKEFKDKEAMYEEVMNVSTDELDGNDNEALIEVVISNPKKPILNDKTFLIDTPGYNGNERAKELVMRTCQVSDIIVFVMTYVFSDEEKEMFKLISEKTSKLNLFILVNKWDESDSDETFTVKMSKDMIEGRFVDWFKDYNDTERNTAKSRIFFISAKEQMDSFMEAKEGINEYRKEEFKRFITELNKSLSDPKFCKCLKHEQDITNMENDMKADIDITINDLEEIIHSRSKSISELRNIKSSLK 1159 MPEDTYLETLNKIQEKSSNLCKFVESIHGFEKELRETCRTFDEEKYDKIFTLNESCESLLSRIRARQLKINNIREILNKSEINVIFVGGVSTGKSKIINSILEEEILPSSIGVTNTKVVRLTGSNNGTSCIKGCDKEFKDKEAMYEEVMNVSTDELDGNDNEALIEVVISNPKKPILNDKTFLIDTPGYNGNERAKELVMRTCQVSDIIVFVMTYVFSDEEKEMFKLISEKTSKLNLFILVNKWDESDSDETFTVKMSKDMIEGRFVDWFKDYNDTERNTAKSRIFFISAKEQMDSFMEAKEGINEYRKEEFKRFITELNKSLSDPKFCKCLKHEQDITNMENDMKADIDITINDLEEIIHSRSKSISELRNIKSSLK Sbjct: 1 MPEDTYLETLNKIQEKSSNLCKFVESIHGFEKELRETCRTFDEEKYDKIFTLNESCESLLSRIRARQLKINNIREILNKSEINVIFVGGVSTGKSKIINSILEEEILPSSIGVTNTKVVRLTGSNNGTSCIKGCDKEFKDKEAMYEEVMNVSTDELDGNDNEALIEVVISNPKKPILNDKTFLIDTPGYNGNERAKELVMRTCQVSDIIVFVMTYVFSDEEKEMFKLISEKTSKLNLFILVNKWDESDSDETFTVKMSKDMIEGRFVDWFKDYNDTERNTAKSRIFFISAKEQMDSFMEAKEGINEYRKEEFKRFITELNKSLSDPKFCKCLKHEQDITNMENDMKADIDITINDLEEIIHSRSKSISELRNIKSSLK 378 HSP 2 Score: 108.612 bits (270), Expect = 9.632e-25 Identity = 76/254 (29.92%), Postives = 129/254 (50.79%), Query Frame = 2 Query: 1778 TIENFVKKYEIIETKVRFIEGKVKKDSIKISFFGTVSAGKSKVLNTIIGENLFLSAVADTTSCFVAVRKSDRGRHYLRVEGSETNFDSLTNLKNKVKELTTHLSENTTGRLDTTKTVQVFL-NIENEIMKNNTEIFDCPGSNNKREVTECIMQQSLDSDIFIFVMTCTLTNEEKDFFEYQSKLSSKPDIFVLVNKWDKSDQDKTAVTEKSRIKIKREIVNLLTKDGNFSSEEASKRIFFVSALEMFKCRIERKE 2536 + E+ + + + K+ I + K I + F G VS GKSK++N+I+ E + S++ T + V + S+ G ++ G + F K + E ++S + D ++V + N + I+ + T + D PG N E +M+ SDI +FVMT ++EEK+ F+ S+ +SK ++F+LVNKWD+SD D+T + S+ I+ V+ + A RIFF+SA E +E KE Sbjct: 55 SCESLLSRIRARQLKINNIREILNKSEINVIFVGGVSTGKSKIINSILEEEILPSSIGVTNTKVVRLTGSNNGTSCIK--GCDKEFKD----KEAMYEEVMNVSTDELDGNDNEALIEVVISNPKKPILNDKTFLIDTPGYNGNERAKELVMRTCQVSDIIVFVMTYVFSDEEKEMFKLISEKTSKLNLFILVNKWDESDSDETFTVKMSKDMIEGRFVDWFKDYNDTERNTAKSRIFFISAKEQMDSFMEAKE 302
BLAST of Dynamin-type G domain-containing protein vs. Planmine SMEST
Match: SMESG000014761.1 (SMESG000014761.1) HSP 1 Score: 698.353 bits (1801), Expect = 0.000e+0 Identity = 345/381 (90.55%), Postives = 363/381 (95.28%), Query Frame = 2 Query: 2 LTFVFI*TMPEDTYLETLNKIQEKSSNLCKFVESIHGFEKELRETCRTFDEEKYDKIFTLNESCESLLSRIRARQLKINNIREILNKSEINVIFVGGVSTGKSKIINSILEEEILPSSIGVTNTKVVRLTGSNNGTSCIKGCDKEFKDKEAMYEEVMNVSTDELDGNDNEALIEVVISNPKKPILNDKTFLIDTPGYNGNERAKELVMRTCQVSDIIVFVMTYVFSDEEKEMFKLISEKTSKLNLFILVNKWDESDSDETFTVKMSKDMIEGRFVDWFKDYNDTERNTAKSRIFFISAKEQMDSFMEAKEGINEYRKEEFKRFITELNKSLSDPKFCKCLKHEQDITNMENDMKADIDITINDLEEIIHSRSKSISELRNI 1144 + F + TM + Y+E L KI++KSSNLCKF+ESIHGFEKELRETC+TFDEEKYDKIFTLNESCESLLSRIRARQLKINNIREILNKSEINVIFVGGVSTGKSKIINSILEEEIL SSIGVTNTKVVRLTGSNNGTSCIKGCDKEFKD +A+Y+EVMNVSTDELDGNDNEALIEVVISNPKK ILNDKTFLIDTPGYNGNERAKELVMRTCQVSDIIVFVMTYVFSDEEKEMFKLISEKTSKLNLFILVNKWDESDSDETFTVKMSKDMIEGRFVDWFKDYNDTERNTAKSRIFFISA+EQMDSFME KEGINEYRK EF+RFITELNKSLSDPKFCKCLKHEQDI NMEND+KADIDITINDL EII+SR+KS +L+NI Sbjct: 6 IAFDYFQTMSVNKYVERLEKIEKKSSNLCKFIESIHGFEKELRETCKTFDEEKYDKIFTLNESCESLLSRIRARQLKINNIREILNKSEINVIFVGGVSTGKSKIINSILEEEILSSSIGVTNTKVVRLTGSNNGTSCIKGCDKEFKDNKALYKEVMNVSTDELDGNDNEALIEVVISNPKKTILNDKTFLIDTPGYNGNERAKELVMRTCQVSDIIVFVMTYVFSDEEKEMFKLISEKTSKLNLFILVNKWDESDSDETFTVKMSKDMIEGRFVDWFKDYNDTERNTAKSRIFFISAEEQMDSFMEGKEGINEYRKGEFERFITELNKSLSDPKFCKCLKHEQDIINMENDVKADIDITINDLTEIINSRTKSSEKLQNI 386 HSP 2 Score: 108.227 bits (269), Expect = 9.529e-24 Identity = 78/255 (30.59%), Postives = 130/255 (50.98%), Query Frame = 2 Query: 1778 TIENFVKKYEIIETKVRFIEGKVKKDSIKISFFGTVSAGKSKVLNTIIGENLFLSAVADTTSCFVAVRKSDRGRHYLRVEGSETNFDSLTNLKNKVKELTT-HLSENTTGRLDTTKTVQVFL-NIENEIMKNNTEIFDCPGSNNKREVTECIMQQSLDSDIFIFVMTCTLTNEEKDFFEYQSKLSSKPDIFVLVNKWDKSDQDKTAVTEKSRIKIKREIVNLLTKDGNFSSEEASKRIFFVSALEMFKCRIERKE 2536 + E+ + + + K+ I + K I + F G VS GKSK++N+I+ E + S++ T + V + S+ G ++ G + F L +V ++T L N D ++V + N + I+ + T + D PG N E +M+ SDI +FVMT ++EEK+ F+ S+ +SK ++F+LVNKWD+SD D+T + S+ I+ V+ + A RIFF+SA E +E KE Sbjct: 68 SCESLLSRIRARQLKINNIREILNKSEINVIFVGGVSTGKSKIINSILEEEILSSSIGVTNTKVVRLTGSNNGTSCIK--GCDKEFKDNKALYKEVMNVSTDELDGN-----DNEALIEVVISNPKKTILNDKTFLIDTPGYNGNERAKELVMRTCQVSDIIVFVMTYVFSDEEKEMFKLISEKTSKLNLFILVNKWDESDSDETFTVKMSKDMIEGRFVDWFKDYNDTERNTAKSRIFFISAEEQMDSFMEGKE 315
BLAST of Dynamin-type G domain-containing protein vs. Planmine SMEST
Match: SMESG000014761.1 (SMESG000014761.1) HSP 1 Score: 694.115 bits (1790), Expect = 0.000e+0 Identity = 343/373 (91.96%), Postives = 359/373 (96.25%), Query Frame = 2 Query: 26 MPEDTYLETLNKIQEKSSNLCKFVESIHGFEKELRETCRTFDEEKYDKIFTLNESCESLLSRIRARQLKINNIREILNKSEINVIFVGGVSTGKSKIINSILEEEILPSSIGVTNTKVVRLTGSNNGTSCIKGCDKEFKDKEAMYEEVMNVSTDELDGNDNEALIEVVISNPKKPILNDKTFLIDTPGYNGNERAKELVMRTCQVSDIIVFVMTYVFSDEEKEMFKLISEKTSKLNLFILVNKWDESDSDETFTVKMSKDMIEGRFVDWFKDYNDTERNTAKSRIFFISAKEQMDSFMEAKEGINEYRKEEFKRFITELNKSLSDPKFCKCLKHEQDITNMENDMKADIDITINDLEEIIHSRSKSISELRNI 1144 M + Y+E L KI++KSSNLCKF+ESIHGFEKELRETC+TFDEEKYDKIFTLNESCESLLSRIRARQLKINNIREILNKSEINVIFVGGVSTGKSKIINSILEEEIL SSIGVTNTKVVRLTGSNNGTSCIKGCDKEFKD +A+Y+EVMNVSTDELDGNDNEALIEVVISNPKK ILNDKTFLIDTPGYNGNERAKELVMRTCQVSDIIVFVMTYVFSDEEKEMFKLISEKTSKLNLFILVNKWDESDSDETFTVKMSKDMIEGRFVDWFKDYNDTERNTAKSRIFFISA+EQMDSFME KEGINEYRK EF+RFITELNKSLSDPKFCKCLKHEQDI NMEND+KADIDITINDL EII+SR+KS +L+NI Sbjct: 1 MSVNKYVERLEKIEKKSSNLCKFIESIHGFEKELRETCKTFDEEKYDKIFTLNESCESLLSRIRARQLKINNIREILNKSEINVIFVGGVSTGKSKIINSILEEEILSSSIGVTNTKVVRLTGSNNGTSCIKGCDKEFKDNKALYKEVMNVSTDELDGNDNEALIEVVISNPKKTILNDKTFLIDTPGYNGNERAKELVMRTCQVSDIIVFVMTYVFSDEEKEMFKLISEKTSKLNLFILVNKWDESDSDETFTVKMSKDMIEGRFVDWFKDYNDTERNTAKSRIFFISAEEQMDSFMEGKEGINEYRKGEFERFITELNKSLSDPKFCKCLKHEQDIINMENDVKADIDITINDLTEIINSRTKSSEKLQNI 373 HSP 2 Score: 108.227 bits (269), Expect = 9.583e-24 Identity = 78/255 (30.59%), Postives = 130/255 (50.98%), Query Frame = 2 Query: 1778 TIENFVKKYEIIETKVRFIEGKVKKDSIKISFFGTVSAGKSKVLNTIIGENLFLSAVADTTSCFVAVRKSDRGRHYLRVEGSETNFDSLTNLKNKVKELTT-HLSENTTGRLDTTKTVQVFL-NIENEIMKNNTEIFDCPGSNNKREVTECIMQQSLDSDIFIFVMTCTLTNEEKDFFEYQSKLSSKPDIFVLVNKWDKSDQDKTAVTEKSRIKIKREIVNLLTKDGNFSSEEASKRIFFVSALEMFKCRIERKE 2536 + E+ + + + K+ I + K I + F G VS GKSK++N+I+ E + S++ T + V + S+ G ++ G + F L +V ++T L N D ++V + N + I+ + T + D PG N E +M+ SDI +FVMT ++EEK+ F+ S+ +SK ++F+LVNKWD+SD D+T + S+ I+ V+ + A RIFF+SA E +E KE Sbjct: 55 SCESLLSRIRARQLKINNIREILNKSEINVIFVGGVSTGKSKIINSILEEEILSSSIGVTNTKVVRLTGSNNGTSCIK--GCDKEFKDNKALYKEVMNVSTDELDGN-----DNEALIEVVISNPKKTILNDKTFLIDTPGYNGNERAKELVMRTCQVSDIIVFVMTYVFSDEEKEMFKLISEKTSKLNLFILVNKWDESDSDETFTVKMSKDMIEGRFVDWFKDYNDTERNTAKSRIFFISAEEQMDSFMEGKE 302
BLAST of Dynamin-type G domain-containing protein vs. Planmine SMEST
Match: SMESG000014761.1 (SMESG000014761.1) HSP 1 Score: 694.115 bits (1790), Expect = 0.000e+0 Identity = 343/373 (91.96%), Postives = 359/373 (96.25%), Query Frame = 2 Query: 26 MPEDTYLETLNKIQEKSSNLCKFVESIHGFEKELRETCRTFDEEKYDKIFTLNESCESLLSRIRARQLKINNIREILNKSEINVIFVGGVSTGKSKIINSILEEEILPSSIGVTNTKVVRLTGSNNGTSCIKGCDKEFKDKEAMYEEVMNVSTDELDGNDNEALIEVVISNPKKPILNDKTFLIDTPGYNGNERAKELVMRTCQVSDIIVFVMTYVFSDEEKEMFKLISEKTSKLNLFILVNKWDESDSDETFTVKMSKDMIEGRFVDWFKDYNDTERNTAKSRIFFISAKEQMDSFMEAKEGINEYRKEEFKRFITELNKSLSDPKFCKCLKHEQDITNMENDMKADIDITINDLEEIIHSRSKSISELRNI 1144 M + Y+E L KI++KSSNLCKF+ESIHGFEKELRETC+TFDEEKYDKIFTLNESCESLLSRIRARQLKINNIREILNKSEINVIFVGGVSTGKSKIINSILEEEIL SSIGVTNTKVVRLTGSNNGTSCIKGCDKEFKD +A+Y+EVMNVSTDELDGNDNEALIEVVISNPKK ILNDKTFLIDTPGYNGNERAKELVMRTCQVSDIIVFVMTYVFSDEEKEMFKLISEKTSKLNLFILVNKWDESDSDETFTVKMSKDMIEGRFVDWFKDYNDTERNTAKSRIFFISA+EQMDSFME KEGINEYRK EF+RFITELNKSLSDPKFCKCLKHEQDI NMEND+KADIDITINDL EII+SR+KS +L+NI Sbjct: 1 MSVNKYVERLEKIEKKSSNLCKFIESIHGFEKELRETCKTFDEEKYDKIFTLNESCESLLSRIRARQLKINNIREILNKSEINVIFVGGVSTGKSKIINSILEEEILSSSIGVTNTKVVRLTGSNNGTSCIKGCDKEFKDNKALYKEVMNVSTDELDGNDNEALIEVVISNPKKTILNDKTFLIDTPGYNGNERAKELVMRTCQVSDIIVFVMTYVFSDEEKEMFKLISEKTSKLNLFILVNKWDESDSDETFTVKMSKDMIEGRFVDWFKDYNDTERNTAKSRIFFISAEEQMDSFMEGKEGINEYRKGEFERFITELNKSLSDPKFCKCLKHEQDIINMENDVKADIDITINDLTEIINSRTKSSEKLQNI 373 HSP 2 Score: 108.227 bits (269), Expect = 8.895e-24 Identity = 78/255 (30.59%), Postives = 130/255 (50.98%), Query Frame = 2 Query: 1778 TIENFVKKYEIIETKVRFIEGKVKKDSIKISFFGTVSAGKSKVLNTIIGENLFLSAVADTTSCFVAVRKSDRGRHYLRVEGSETNFDSLTNLKNKVKELTT-HLSENTTGRLDTTKTVQVFL-NIENEIMKNNTEIFDCPGSNNKREVTECIMQQSLDSDIFIFVMTCTLTNEEKDFFEYQSKLSSKPDIFVLVNKWDKSDQDKTAVTEKSRIKIKREIVNLLTKDGNFSSEEASKRIFFVSALEMFKCRIERKE 2536 + E+ + + + K+ I + K I + F G VS GKSK++N+I+ E + S++ T + V + S+ G ++ G + F L +V ++T L N D ++V + N + I+ + T + D PG N E +M+ SDI +FVMT ++EEK+ F+ S+ +SK ++F+LVNKWD+SD D+T + S+ I+ V+ + A RIFF+SA E +E KE Sbjct: 55 SCESLLSRIRARQLKINNIREILNKSEINVIFVGGVSTGKSKIINSILEEEILSSSIGVTNTKVVRLTGSNNGTSCIK--GCDKEFKDNKALYKEVMNVSTDELDGN-----DNEALIEVVISNPKKTILNDKTFLIDTPGYNGNERAKELVMRTCQVSDIIVFVMTYVFSDEEKEMFKLISEKTSKLNLFILVNKWDESDSDETFTVKMSKDMIEGRFVDWFKDYNDTERNTAKSRIFFISAEEQMDSFMEGKE 302 The following BLAST results are available for this feature:
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 1
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 4
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Dynamin-type G domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Dynamin-type G domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 4
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 0
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 1
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 4
BLAST of Dynamin-type G domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30020268 ID=SMED30020268|Name=Dynamin-type G domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=3959bpback to top protein sequence of SMED30020268-orf-1 >SMED30020268-orf-1 ID=SMED30020268-orf-1|Name=SMED30020268-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=207bp MKNNTEIFDCPGSNNKREVTECIMQQSLDSDIFIFVMTCTLTNEEKDFFEback to top protein sequence of SMED30020268-orf-2 >SMED30020268-orf-2 ID=SMED30020268-orf-2|Name=SMED30020268-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=129bp MILHYNVQANFQVPMFILFQLLLRSPVILVIANNIIQTHASKTPTVLENQback to top protein sequence of SMED30020268-orf-3 >SMED30020268-orf-3 ID=SMED30020268-orf-3|Name=SMED30020268-orf-3|organism=Schmidtea mediterranea sexual|type=polypeptide|length=499bp MPEDTYLETLNKIQEKSSNLCKFVESIHGFEKELRETCRTFDEEKYDKIFback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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