N6-adenosine-methyltransferase subunit

Overview
NameN6-adenosine-methyltransferase subunit
Smed IDSMED30020264
Length (bp)1743
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of N6-adenosine-methyltransferase subunit (SMED30020264) t-SNE clustered cells

Violin plots show distribution of expression levels for N6-adenosine-methyltransferase subunit (SMED30020264) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of N6-adenosine-methyltransferase subunit (SMED30020264) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for N6-adenosine-methyltransferase subunit (SMED30020264) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30020264

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 1

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X2 cellSMED30020264SMESG000034548.1 SmedASXL_008905SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of N6-adenosine-methyltransferase subunit vs. Ensembl Human
Match: METTL3 (methyltransferase like 3 [Source:HGNC Symbol;Acc:HGNC:17563])

HSP 1 Score: 522.702 bits (1345), Expect = 3.125e-180
Identity = 260/462 (56.28%), Postives = 328/462 (71.00%), Query Frame = 3 
Query:  474 VDSCLEKFSLQQFIKLK----PDEMHSTIFYVSYIDHDKISIFL---------------------EDNKDDDAYKLENNNLI-----------KEEFCKLEN---------IENLLGAQTAKEKETKRVNDEITYLLDRASAKEQSLIERFKSQRGSNVQQFCHYGTKEECSKVNEI---CKKLHFRKIIQAHTDESLGDCSFLNTCFHIESCKYVHYEINQ------PDS-----IQEDNNGKYLGIHARHDTTSLYQPQWIECDIRELDMSILGKFAVIMADPPWDIHMELPYGTMSDEEMSRLDIPCLQTEGYIFLWVTGRAMEQGRECLRLWGYQCLEEIIWVKTNQLQRIIRTGRTGHWINHGKEHCLVGVKGNPKGMNRGLDCDVIVSEVRETSHKPDEIYGIIERLSPGTRKLELFGRPHNLQPNWITLGNQLEGTKLVDPEVVERFRKRYPDGL 1682
            V+S L+KF+ Q+ I++K     D+ H T+  V+Y DH K+S  +                        +D        ++L+           KE   K            IE+LL  Q+ KE+++K+V+ EI  LL+  +AKEQS++E+F+S+  + VQ+FC YGTKEEC K ++    C+KLHFR+II  HTDESLGDCSFLNTCFH+++CKYVHYEI+       P S      QE    + +G  +  D   L+ PQWI CDIR LD+SILGKFAV+MADPPWDIHMELPYGT++D+EM RL+IP LQ +G++FLWVTGRAME GRECL LWGY+ ++EIIWVKTNQLQRIIRTGRTGHW+NHGKEHCLVGVKGNP+G N+GLDCDVIV+EVR TSHKPDEIYG+IERLSPGTRK+ELFGRPHN+QPNWITLGNQL+G  L+DP+VV RF++RYPDG+
Sbjct:  116 VESLLQKFAAQELIEVKRGLLQDDAHPTL--VTYADHSKLSAMMGAVAEKKGPGEVAGTVTGQKRRAEQDSTTVAAFASSLVSGLNSSASEPAKEPAKKSRKHAASDVDLEIESLLNQQSTKEQQSKKVSQEILELLNTTTAKEQSIVEKFRSRGRAQVQEFCDYGTKEECMKASDADRPCRKLHFRRIINKHTDESLGDCSFLNTCFHMDTCKYVHYEIDACMDSEAPGSKDHTPSQELALTQSVGGDSSAD--RLFPPQWICCDIRYLDVSILGKFAVVMADPPWDIHMELPYGTLTDDEMRRLNIPVLQDDGFLFLWVTGRAMELGRECLNLWGYERVDEIIWVKTNQLQRIIRTGRTGHWLNHGKEHCLVGVKGNPQGFNQGLDCDVIVAEVRSTSHKPDEIYGMIERLSPGTRKIELFGRPHNVQPNWITLGNQLDGIHLLDPDVVARFKQRYPDGI 573
[Close]
BLAST of N6-adenosine-methyltransferase subunit vs. Ensembl Human
Match: METTL3 (methyltransferase like 3 [Source:HGNC Symbol;Acc:HGNC:17563])

HSP 1 Score: 154.066 bits (388), Expect = 2.457e-41
Identity = 90/222 (40.54%), Postives = 129/222 (58.11%), Query Frame = 3 
Query:  474 VDSCLEKFSLQQFIKLK----PDEMHSTIFYVSYIDHDKISIFL------------------------EDNKDDDAYK---LENNNLIKEEFCK---------------LENIENLLGAQTAKEKETKRVNDEITYLLDRASAKEQSLIERFKSQRGSNVQQFCHYGTKEECSKVNEI---CKKLHFRKIIQAHTDESLGDCSFLNTCFHIESCKYVHYEIN 992
            V+S L+KF+ Q+ I++K     D+ H T+  V+Y DH K+S  +                        +D+    A+    +   N    E  K               LE IE+LL  Q+ KE+++K+V+ EI  LL+  +AKEQS++E+F+S+  + VQ+FC YGTKEEC K ++    C+KLHFR+II  HTDESLGDCSFLNTCFH+++CKYVHYEI+
Sbjct:   66 VESLLQKFAAQELIEVKRGLLQDDAHPTL--VTYADHSKLSAMMGAVAEKKGPGEVAGTVTGQKRRAEQDSTTVAAFASSLVSGLNSSASEPAKEPAKKSRKHAASDVDLE-IESLLNQQSTKEQQSKKVSQEILELLNTTTAKEQSIVEKFRSRGRAQVQEFCDYGTKEECMKASDADRPCRKLHFRRIINKHTDESLGDCSFLNTCFHMDTCKYVHYEID 284
[Close]
BLAST of N6-adenosine-methyltransferase subunit vs. Ensembl Human
Match: METTL14 (methyltransferase like 14 [Source:HGNC Symbol;Acc:HGNC:29330])

HSP 1 Score: 103.99 bits (258), Expect = 4.166e-23
Identity = 68/198 (34.34%), Postives = 105/198 (53.03%), Query Frame = 3 
Query: 1074 PQWIECDIRELDM-SILGKFAVIMADPPWDIHMELPYGTMSDEEMSRLDIPCLQTE------GYIFLWV-TGRAMEQGRECLRLWGYQCLEEIIWVKTNQLQR-IIRTGRTGHWINHGKEHCLVGVKGNPKGMNRG------LDCDVIVSEVRETSH--KPDEIYGIIERLSPGTRKLELFGRPHNLQPNWITLGNQL 1616
            P +++ DI   D+  +  KF VI+ +PP + +      T +++  +  DI  L+ +       +IFLW  +G  ++ GR CLR WGY+  E+I W+KTN+      +T          KEHCL+G+KG  K    G      +D D+I++E  E  +  KP EI+ IIE    G R+L LFGR   ++P W+T+G  L
Sbjct:  167 PMYLQADIEAFDIRELTPKFDVILLEPPLEEYYRETGITANEKCWTWDDIMKLEIDEIAAPRSFIFLWCGSGEGLDLGRVCLRKWGYRRCEDICWIKTNKNNPGKTKTLDPKAVFQRTKEHCLMGIKGTVKRSTDGDFIHANVDIDLIITEEPEIGNIEKPVEIFHIIEHFCLGRRRLHLFGRDSTIRPGWLTVGPTL 364
[Close]
BLAST of N6-adenosine-methyltransferase subunit vs. Ensembl Human
Match: METTL14 (methyltransferase like 14 [Source:HGNC Symbol;Acc:HGNC:29330])

HSP 1 Score: 48.9062 bits (115), Expect = 2.287e-6
Identity = 33/92 (35.87%), Postives = 51/92 (55.43%), Query Frame = 3 
Query: 1095 IRELDMSILGKFAVIMADPPWDIHMELPYGTMSDEEMSRLDIPCLQTE------GYIFLWV-TGRAMEQGRECLRLWGYQCLEEIIWVKTNQ 1349
            IREL      KF VI+ +PP + +      T +++  +  DI  L+ +       +IFLW  +G  ++ GR CLR WGY+  E+I W+KTN+
Sbjct:    2 IRELT----PKFDVILLEPPLEEYYRETGITANEKCWTWDDIMKLEIDEIAAPRSFIFLWCGSGEGLDLGRVCLRKWGYRRCEDICWIKTNK 89
[Close]
BLAST of N6-adenosine-methyltransferase subunit vs. Ensembl Fly
Match: Mettl3 (gene:FBgn0039139 transcript:FBtr0084532)

HSP 1 Score: 462.611 bits (1189), Expect = 1.082e-156
Identity = 203/289 (70.24%), Postives = 242/289 (83.74%), Query Frame = 3 
Query:  834 GTKEECSKVNEICKKLHFRKIIQAHTDESLGDCSFLNTCFHIESCKYVHYEINQPDSIQEDNNGKYLGIHAR-------HDTTSLYQPQWIECDIRELDMSILGKFAVIMADPPWDIHMELPYGTMSDEEMSRLDIPCLQTEGYIFLWVTGRAMEQGRECLRLWGYQCLEEIIWVKTNQLQRIIRTGRTGHWINHGKEHCLVGVKGNPKGMNRGLDCDVIVSEVRETSHKPDEIYGIIERLSPGTRKLELFGRPHNLQPNWITLGNQLEGTKLVDPEVVERFRKRYPDG 1679
            G+    S+  + C KLHF+KIIQAHTDESLGDCSFLNTCFH+ +CKYVHYE+   D++   N  K   +  +         + +LY PQWI+CD+R LDM++LGKFAV+MADPPWDIHMELPYGTMSD+EM  L +P LQ +G IFLWVTGRAME GR+CL+LWGY+ ++E+IWVKTNQLQRIIRTGRTGHW+NHGKEHCLVG+KGNP  +NRGLDCDVIV+EVR TSHKPDEIYGIIERLSPGTRK+ELFGRPHN+QPNWITLGNQL+G +LVDPE++ +F+KRYPDG
Sbjct:  305 GSDTCSSETTDKCTKLHFKKIIQAHTDESLGDCSFLNTCFHMATCKYVHYEV---DTLPHINTNKPTDVKTKLSLKRSVDSSCTLYPPQWIQCDLRFLDMTVLGKFAVVMADPPWDIHMELPYGTMSDDEMRALGVPALQDDGLIFLWVTGRAMELGRDCLKLWGYERVDELIWVKTNQLQRIIRTGRTGHWLNHGKEHCLVGMKGNPTNLNRGLDCDVIVAEVRATSHKPDEIYGIIERLSPGTRKIELFGRPHNIQPNWITLGNQLDGIRLVDPELITQFQKRYPDG 590

HSP 2 Score: 73.559 bits (179), Expect = 2.470e-13
Identity = 78/287 (27.18%), Postives = 132/287 (45.99%), Query Frame = 3 
Query:   45 MGDTWKDIQEVKNKKTSIREKLENRKRQRENLMASVNVVPIKKHANNEVKKLSNNIYIMKHSTLKKCIEDPLTLD--NNDDLSNVVGMTECYDNILHDDKIINSNVENQMLTIISNLTTREELSNKDIHDIIVQKEPQLKLEGLIVDSCLEKFSLQQFIKLKPDEMHSTIFYVSYIDHDKISIFLEDNKDDDAYKLENNNLIKEEFC--KLENIENLLGAQTAKEKETKRVNDEITYLLDRASAKEQSLIERFKSQRGSNVQQFCHYGTKEECSKVNEICKKLHFRK 893
            M D W DI+ +K K+ ++REKLE RK++R  +++      I++   N  K+L      ++   L+      L L   +   +  + G +      L     I   + NQ   +I N+T   E   + I   +  KE +  LE    D+C +K   +   KL+ D++                    D   +   KLE+    KE       ++I  LL   + +EK++K+V +EI  LL + +AKE+S+ E+FKS  G+ V +FC +GTK EC K  +   ++  +K
Sbjct:    1 MADAW-DIKSLKTKRNTLREKLEKRKKERIEILSD-----IQEDLTNPKKELVEADLEVQKEVLQALSSCSLALPIVSTQVVEKIAGSS------LEMVNFILGKLANQGAIVIRNVTIGTEAGCEIIS--VQPKELKEILED-TNDTCQQKEE-EAKRKLEVDDV--------------------DQPQEKTIKLESTVARKESTSLDAPDDIMMLLSMPSTREKQSKQVGEEILELLTKPTAKERSVAEKFKSHGGAQVMEFCSHGTKVECLKAQQATAEMAAKK 251
[Close]
BLAST of N6-adenosine-methyltransferase subunit vs. Ensembl Fly
Match: Mettl14 (gene:FBgn0032016 transcript:FBtr0079599)

HSP 1 Score: 97.8265 bits (242), Expect = 1.498e-21
Identity = 69/220 (31.36%), Postives = 109/220 (49.55%), Query Frame = 3 
Query: 1050 HDTTSLYQPQWIECDIRELDMSILG-KFAVIMADPPWDIHMELPYGTMSDEEMSRL-----DIPCLQT------EGYIFLWV-TGRAMEQGRECLRLWGYQCLEEIIWVKTNQLQRIIRTGRTGHW-----INHGKEHCLVGVKGNPKGMNRG------LDCDVIVSEVRETSH--KPDEIYGIIERLSPGTRKLELFGRPHNLQPNWITLGNQLEGTKL 1631
             DT S   P +++ D++ LD+  LG KF VI+ +PP + +        +     R+     DI  L          ++FLW  +   ++ GR CL+ WG++  E+I W++TN    I + G +            KEHCL+G+KG  +    G      +D D+I+SE  E     KP EI+ IIE    G R+L LFGR  +++P W+T+G +L  +  
Sbjct:  133 QDTAS--APMYLKADLKSLDVKTLGAKFDVILIEPPLEEYARAAPSVATVGGAPRVFWNWDDILNLDVGEIAAHRSFVFLWCGSSEGLDMGRNCLKKWGFRRCEDICWIRTN----INKPGHSKQLEPKAVFQRTKEHCLMGIKGTVRRSTDGDFIHANVDIDLIISEEEEFGSFEKPIEIFHIIEHFCLGRRRLHLFGRDSSIRPGWLTVGPELTNSNF 346
[Close]
BLAST of N6-adenosine-methyltransferase subunit vs. Ensembl Zebrafish
Match: mettl3 (methyltransferase like 3 [Source:NCBI gene;Acc:100004398])

HSP 1 Score: 525.783 bits (1353), Expect = 0.000e+0
Identity = 242/367 (65.94%), Postives = 297/367 (80.93%), Query Frame = 3 
Query:  615 AYKLENNNLIKEEFCKLENIENLLGAQTAKEKETKRVNDEITYLLDRASAKEQSLIERFKSQRGSNVQQFCHYGTKEECSKVNEI---CKKLHFRKIIQAHTDESLGDCSFLNTCFHIESCKYVHYEINQP-----DSIQEDNNGKYLGIHAR---HDTTSLYQPQWIECDIRELDMSILGKFAVIMADPPWDIHMELPYGTMSDEEMSRLDIPCLQTEGYIFLWVTGRAMEQGRECLRLWGYQCLEEIIWVKTNQLQRIIRTGRTGHWINHGKEHCLVGVKGNPKGMNRGLDCDVIVSEVRETSHKPDEIYGIIERLSPGTRKLELFGRPHNLQPNWITLGNQLEGTKLVDPEVVERFRKRYPDGL 1682
            A K   +N ++     +E IE+LL  Q+ KE+++K+V+ EI  LL+ +SAKEQS++E+F+S+  + VQ+FC YGTKEEC +  +    C KLHFR+II  HTDESLGDCSFLNTCFH+++CKYVHYEI+ P     D++        LG+H+     +   L+  QWI CDIR LD+SILGKFAV+MADPPWDIHMELPYGT++D+EM +L+IP LQ +G++FLWVTGRAME GRECL LWGY  ++EIIWVKTNQLQRIIRTGRTGHW+NHGKEHCLVGVKGNP+G NRGLDCDVIV+EVR TSHKPDEIYG+IERLSPGTRK+ELFGRPHN+QPNWITLGNQL+G  L+DPEVV RF+KRYPDG+
Sbjct:  212 ADKKGRSNKVQASHLDME-IESLLSQQSTKEQQSKKVSQEILELLNTSSAKEQSIVEKFRSRGRAQVQEFCDYGTKEECVQSGDTPQPCTKLHFRRIINKHTDESLGDCSFLNTCFHMDTCKYVHYEIDSPPEAEGDALGPQAGAAELGLHSTVGDSNVGKLFPSQWICCDIRYLDVSILGKFAVVMADPPWDIHMELPYGTLTDDEMRKLNIPILQDDGFLFLWVTGRAMELGRECLSLWGYDRVDEIIWVKTNQLQRIIRTGRTGHWLNHGKEHCLVGVKGNPQGFNRGLDCDVIVAEVRSTSHKPDEIYGMIERLSPGTRKIELFGRPHNVQPNWITLGNQLDGIHLLDPEVVARFKKRYPDGV 577
[Close]
BLAST of N6-adenosine-methyltransferase subunit vs. Ensembl Zebrafish
Match: mettl14 (methyltransferase like 14 [Source:NCBI gene;Acc:404603])

HSP 1 Score: 97.8265 bits (242), Expect = 2.943e-21
Identity = 65/204 (31.86%), Postives = 108/204 (52.94%), Query Frame = 3 
Query: 1074 PQWIECDIRELDMSILG-KFAVIMADPPWDIHMELPYGTMSDE------EMSRLDIPCLQT-EGYIFLWV-TGRAMEQGRECLRLWGYQCLEEIIWVKTNQLQR-IIRTGRTGHWINHGKEHCLVGVKGNPKGMNRG------LDCDVIVSEVRETSH--KPDEIYGIIERLSPGTRKLELFGRPHNLQPNWITLGNQLEGTKL 1631
            P +++ D    D+  L  KF VI+ +PP + +     G +++E      ++ +L+I  + +   ++FLW  +G  ++ GR CLR WG++  E+I W+KTN+      +T          KEHCL+G+KG  +    G      +D D+I++E  E  +  KP EI+ IIE    G R+L LFGR   ++P W+T+G  L  +  
Sbjct:  166 PMYLQADPDTFDLRELKCKFDVILIEPPLEEYYR-ESGIIANERFWNWDDIMKLNIEEISSIRSFVFLWCGSGEGLDLGRMCLRKWGFRRCEDICWIKTNKNNPGKTKTLDPKAVFQRTKEHCLMGIKGTVRRSTDGDFIHANVDIDLIITEEPEMGNIEKPVEIFHIIEHFCLGRRRLHLFGRDSTIRPGWLTVGPTLTNSNF 368
[Close]
BLAST of N6-adenosine-methyltransferase subunit vs. Ensembl Zebrafish
Match: mettl14 (methyltransferase like 14 [Source:NCBI gene;Acc:404603])

HSP 1 Score: 97.8265 bits (242), Expect = 2.943e-21
Identity = 65/204 (31.86%), Postives = 108/204 (52.94%), Query Frame = 3 
Query: 1074 PQWIECDIRELDMSILG-KFAVIMADPPWDIHMELPYGTMSDE------EMSRLDIPCLQT-EGYIFLWV-TGRAMEQGRECLRLWGYQCLEEIIWVKTNQLQR-IIRTGRTGHWINHGKEHCLVGVKGNPKGMNRG------LDCDVIVSEVRETSH--KPDEIYGIIERLSPGTRKLELFGRPHNLQPNWITLGNQLEGTKL 1631
            P +++ D    D+  L  KF VI+ +PP + +     G +++E      ++ +L+I  + +   ++FLW  +G  ++ GR CLR WG++  E+I W+KTN+      +T          KEHCL+G+KG  +    G      +D D+I++E  E  +  KP EI+ IIE    G R+L LFGR   ++P W+T+G  L  +  
Sbjct:  166 PMYLQADPDTFDLRELKCKFDVILIEPPLEEYYR-ESGIIANERFWNWDDIMKLNIEEISSIRSFVFLWCGSGEGLDLGRMCLRKWGFRRCEDICWIKTNKNNPGKTKTLDPKAVFQRTKEHCLMGIKGTVRRSTDGDFIHANVDIDLIITEEPEMGNIEKPVEIFHIIEHFCLGRRRLHLFGRDSTIRPGWLTVGPTLTNSNF 368
[Close]
BLAST of N6-adenosine-methyltransferase subunit vs. Ensembl Zebrafish
Match: mettl4 (methyltransferase like 4 [Source:ZFIN;Acc:ZDB-GENE-130129-2])

HSP 1 Score: 52.7582 bits (125), Expect = 8.421e-7
Identity = 47/182 (25.82%), Postives = 76/182 (41.76%), Query Frame = 3 
Query: 1125 KFAVIMADPPWD---IHMELPYGTMSDEEMSRLDIPCLQTE-GYIFLWVTGRAMEQ---GRECLRLWGYQCLEEIIWVKTNQLQRIIRTGRTGHWINHGKEHCLVGVKGNPKGMNRGLDCDVIVSEVRET-----------SHKPDEIYGIIERLSPGTRKLELFGRPHNLQPNWITLGNQL 1616
            KF +I+ DPPW+   +     Y ++   ++ +L +P L    G +  WVT RA  +     E    W  + L E +WVK  +    +    + H     K+   V V G  +  +   D    V+E+ +            SHKP     +   +    R LELF R  +LQ +W   GN++
Sbjct:  234 KFDLIVLDPPWENKSVKRSNRYSSLPSSQLKKLPVPALAAPGGLVVTWVTNRAKHRRFVREELYPHWAVEVLAEWLWVKVTRSGEFVFPLDSQH-----KKPYEVLVLGRCRSTSDHTDRCSAVNELPDQRLLVSVPSTLHSHKPSLAAVLKPYIRREPRCLELFAR--SLQSDWSCWGNEV 408
[Close]
BLAST of N6-adenosine-methyltransferase subunit vs. Ensembl Xenopus
Match: kdm1b (lysine (K)-specific demethylase 1B [Source:Xenbase;Acc:XB-GENE-982183])

HSP 1 Score: 514.612 bits (1324), Expect = 2.960e-177
Identity = 231/350 (66.00%), Postives = 287/350 (82.00%), Query Frame = 3 
Query:  672 IENLLGAQTAKEKETKRVNDEITYLLDRASAKEQSLIERFKSQRGSNVQQFCHYGTKEECSKV---NEICKKLHFRKIIQAHTDESLGDCSFLNTCFHIESCKYVHYEINQ----------PDSIQEDNNGKYLGIHARHDTTSLYQPQWIECDIRELDMSILGKFAVIMADPPWDIHMELPYGTMSDEEMSRLDIPCLQTEGYIFLWVTGRAMEQGRECLRLWGYQCLEEIIWVKTNQLQRIIRTGRTGHWINHGKEHCLVGVKGNPKGMNRGLDCDVIVSEVRETSHKPDEIYGIIERLSPGTRKLELFGRPHNLQPNWITLGNQLEGTKLVDPEVVERFRKRYPDGL 1682
            IE+LL  Q+ KE+++K+V+ EI  LL+ ++AKEQS++E+F+S+  + VQ+FC YGTKEEC K    +  C+KLHFR+II  HTDESLGDCSFLNTCFH+++CKYVHYEI+           P+++   +      +        L+  QWI CDIR LDMSILGKF+V+MADPPWDIHMELPYGT++D+EM +L IP LQ +G++FLWVTGRAME GRECL+LWGY+ ++EIIWVKTNQLQRIIRTGRTGHW+NHGKEHCLVGVKGNP+G NRGLDCDVIV+EVR TSHKPDEIYG+IERLSPGTRK+ELFGRPHN+QPNWITLGNQL+G  L+DP+VV RF+++YPDG+
Sbjct:  218 IESLLSQQSTKEQQSKKVSQEILELLNTSTAKEQSIVEKFRSRGRAQVQEFCDYGTKEECMKAAGADTPCRKLHFRRIINMHTDESLGDCSFLNTCFHMDTCKYVHYEIDAWVEPGGTAVVPEAVPSQDTPLTKAV-GDSSVGRLFPSQWIRCDIRYLDMSILGKFSVVMADPPWDIHMELPYGTLTDDEMRKLQIPVLQDDGFLFLWVTGRAMELGRECLKLWGYERVDEIIWVKTNQLQRIIRTGRTGHWLNHGKEHCLVGVKGNPQGFNRGLDCDVIVAEVRSTSHKPDEIYGMIERLSPGTRKIELFGRPHNVQPNWITLGNQLDGIHLLDPDVVARFKQKYPDGV 566
[Close]
BLAST of N6-adenosine-methyltransferase subunit vs. Ensembl Xenopus
Match: kdm1b (lysine (K)-specific demethylase 1B [Source:Xenbase;Acc:XB-GENE-982183])

HSP 1 Score: 471.47 bits (1212), Expect = 7.971e-161
Identity = 212/321 (66.04%), Postives = 261/321 (81.31%), Query Frame = 3 
Query:  672 IENLLGAQTAKEKETKRVNDEITYLLDRASAKEQSLIERFKSQRGSNVQQFCHYGTKEECSKV---NEICKKLHFRKIIQAHTDESLGDCSFLNTCFHIESCKYVHYEINQ----------PDSIQEDNNGKYLGIHARHDTTSLYQPQWIECDIRELDMSILGKFAVIMADPPWDIHMELPYGTMSDEEMSRLDIPCLQTEGYIFLWVTGRAMEQGRECLRLWGYQCLEEIIWVKTNQLQRIIRTGRTGHWINHGKEHCLVGVKGNPKGMNRGLDCDVIVSEVRETSHKPDEIYGIIERLSPGTRKLELFGRPHNLQPNW 1595
            IE+LL  Q+ KE+++K+V+ EI  LL+ ++AKEQS++E+F+S+  + VQ+FC YGTKEEC K    +  C+KLHFR+II  HTDESLGDCSFLNTCFH+++CKYVHYEI+           P+++   +      +        L+  QWI CDIR LDMSILGKF+V+MADPPWDIHMELPYGT++D+EM +L IP LQ +G++FLWVTGRAME GRECL+LWGY+ ++EIIWVKTNQLQRIIRTGRTGHW+NHGKEHCLVGVKGNP+G NRGLDCDVIV+EVR TSHKPDEIYG+IERLSPGTRK+ELFGRPHN+QPNW
Sbjct:  218 IESLLSQQSTKEQQSKKVSQEILELLNTSTAKEQSIVEKFRSRGRAQVQEFCDYGTKEECMKAAGADTPCRKLHFRRIINMHTDESLGDCSFLNTCFHMDTCKYVHYEIDAWVEPGGTAVVPEAVPSQDTPLTKAV-GDSSVGRLFPSQWIRCDIRYLDMSILGKFSVVMADPPWDIHMELPYGTLTDDEMRKLQIPVLQDDGFLFLWVTGRAMELGRECLKLWGYERVDEIIWVKTNQLQRIIRTGRTGHWLNHGKEHCLVGVKGNPQGFNRGLDCDVIVAEVRSTSHKPDEIYGMIERLSPGTRKIELFGRPHNVQPNW 537
[Close]
BLAST of N6-adenosine-methyltransferase subunit vs. Ensembl Xenopus
Match: gbx1 (gastrulation brain homeobox 1 [Source:Xenbase;Acc:XB-GENE-920347])

HSP 1 Score: 100.138 bits (248), Expect = 7.910e-22
Identity = 65/204 (31.86%), Postives = 107/204 (52.45%), Query Frame = 3 
Query: 1074 PQWIECDIRELDMSIL-GKFAVIMADPPWDIHMELPYGTMSDE------EMSRLDIPCLQ-TEGYIFLWV-TGRAMEQGRECLRLWGYQCLEEIIWVKTNQLQR-IIRTGRTGHWINHGKEHCLVGVKGNPKGMNRG------LDCDVIVSEVRETSH--KPDEIYGIIERLSPGTRKLELFGRPHNLQPNWITLGNQLEGTKL 1631
            P +++ D+   D+  L  +F VI+ +PP + +     G  ++E      ++ +LDI  +  +  ++FLW  +G  ++ GR CLR WG++  E+I W+KTN+      +T          KEHCL+G+KG       G      +D D+I++E  E  +  KP EI+ IIE    G R+L LFGR   ++P W+T+G  L  +  
Sbjct:  168 PMYLQADLESFDLRELKSEFDVILLEPPLEEYFR-ETGIAANEKWWTWEDIMKLDIEGIAGSRAFVFLWCGSGEGLDFGRMCLRKWGFRRSEDICWIKTNKDNPGKTKTLDPKAIFQRTKEHCLMGIKGTVHRSTDGDFIHANVDIDLIITEEPEIGNIEKPVEIFHIIEHFCLGRRRLHLFGRDSTIRPGWLTVGPTLTNSNF 370
[Close]
BLAST of N6-adenosine-methyltransferase subunit vs. Ensembl Xenopus
Match: gbx1 (gastrulation brain homeobox 1 [Source:Xenbase;Acc:XB-GENE-920347])

HSP 1 Score: 99.7525 bits (247), Expect = 9.591e-22
Identity = 65/204 (31.86%), Postives = 107/204 (52.45%), Query Frame = 3 
Query: 1074 PQWIECDIRELDMSIL-GKFAVIMADPPWDIHMELPYGTMSDE------EMSRLDIPCLQ-TEGYIFLWV-TGRAMEQGRECLRLWGYQCLEEIIWVKTNQLQR-IIRTGRTGHWINHGKEHCLVGVKGNPKGMNRG------LDCDVIVSEVRETSH--KPDEIYGIIERLSPGTRKLELFGRPHNLQPNWITLGNQLEGTKL 1631
            P +++ D+   D+  L  +F VI+ +PP + +     G  ++E      ++ +LDI  +  +  ++FLW  +G  ++ GR CLR WG++  E+I W+KTN+      +T          KEHCL+G+KG       G      +D D+I++E  E  +  KP EI+ IIE    G R+L LFGR   ++P W+T+G  L  +  
Sbjct:  167 PMYLQADLESFDLRELKSEFDVILLEPPLEEYFR-ETGIAANEKWWTWEDIMKLDIEGIAGSRAFVFLWCGSGEGLDFGRMCLRKWGFRRSEDICWIKTNKDNPGKTKTLDPKAIFQRTKEHCLMGIKGTVHRSTDGDFIHANVDIDLIITEEPEIGNIEKPVEIFHIIEHFCLGRRRLHLFGRDSTIRPGWLTVGPTLTNSNF 369
[Close]
BLAST of N6-adenosine-methyltransferase subunit vs. Ensembl Xenopus
Match: grid1 (glutamate receptor, ionotropic, delta 1 [Source:Xenbase;Acc:XB-GENE-990290])

HSP 1 Score: 53.1434 bits (126), Expect = 8.139e-7
Identity = 51/192 (26.56%), Postives = 81/192 (42.19%), Query Frame = 3 
Query: 1125 KFAVIMADPPWD---IHMELPYGTMSDEEMSRLDIPCLQT-EGYIFLWVTGRAME---QGRECLRLWGYQCLEEIIWVKTNQLQRIIRTGRTGHWI--NHGKEH---CLVGVKG--NPKGMNRGLDCD-------VIVSEVRETSHKPDEIYGIIERLSPGTRKLELFGRPHNLQPNWITLGNQLEGTKLVD 1637
            K+ +I+ DPPW+   +     Y ++S  E+ +L +P L   +  +  WVT +         +    W  + L E  WVK      I R+G     +  NH K +    L   +G  N  G   G+          ++    +  SHKP     + E + P    LELF R  NLQP W + GN++   + +D
Sbjct:  225 KYNIIVMDPPWENKSVKRSKRYNSLSPNEIQQLPVPALAAPDCLVITWVTNKQKHLRFVKEDLYPQWSVRTLGEWHWVK------ITRSGEFVFPLDSNHKKPYEVLVLGRFQGTVNSAGRESGISLPPIPERKLIVSVPCKLHSHKPPLSEVLKEYVKPDVECLELFAR--NLQPGWTSWGNEVLKFQHID 408
[Close]
BLAST of N6-adenosine-methyltransferase subunit vs. Ensembl Mouse
Match: Mettl3 (methyltransferase like 3 [Source:MGI Symbol;Acc:MGI:1927165])

HSP 1 Score: 518.079 bits (1333), Expect = 1.440e-178
Identity = 232/349 (66.48%), Postives = 288/349 (82.52%), Query Frame = 3 
Query:  672 IENLLGAQTAKEKETKRVNDEITYLLDRASAKEQSLIERFKSQRGSNVQQFCHYGTKEECSKVNEI---CKKLHFRKIIQAHTDESLGDCSFLNTCFHIESCKYVHYEINQPDSIQEDNNGKYL---------GIHARHDTTSLYQPQWIECDIRELDMSILGKFAVIMADPPWDIHMELPYGTMSDEEMSRLDIPCLQTEGYIFLWVTGRAMEQGRECLRLWGYQCLEEIIWVKTNQLQRIIRTGRTGHWINHGKEHCLVGVKGNPKGMNRGLDCDVIVSEVRETSHKPDEIYGIIERLSPGTRKLELFGRPHNLQPNWITLGNQLEGTKLVDPEVVERFRKRYPDGL 1682
            IE+LL  Q+ KE+++K+V+ EI  LL+  +AKEQS++E+F+S+  + VQ+FC YGTKEEC K ++    C+KLHFR+II  HTDESLGDCSFLNTCFH+++CKYVHYEI+     +   + +++          +        L+ PQWI CDIR LD+SILGKFAV+MADPPWDIHMELPYGT++D+EM RL+IP LQ +G++FLWVTGRAME GRECL LWGY+ ++EIIWVKTNQLQRIIRTGRTGHW+NHGKEHCLVGVKGNP+G N+GLDCDVIV+EVR TSHKPDEIYG+IERLSPGTRK+ELFGRPHN+QPNWITLGNQL+G  L+DP+VV RF++RYPDG+
Sbjct:  225 IESLLNQQSTKEQQSKKVSQEILELLNTTTAKEQSIVEKFRSRGRAQVQEFCDYGTKEECMKASDADRPCRKLHFRRIINKHTDESLGDCSFLNTCFHMDTCKYVHYEIDACVDSESPGSKEHMPSQELALTQSVGGDSSADRLFPPQWICCDIRYLDVSILGKFAVVMADPPWDIHMELPYGTLTDDEMRRLNIPVLQDDGFLFLWVTGRAMELGRECLNLWGYERVDEIIWVKTNQLQRIIRTGRTGHWLNHGKEHCLVGVKGNPQGFNQGLDCDVIVAEVRSTSHKPDEIYGMIERLSPGTRKIELFGRPHNVQPNWITLGNQLDGIHLLDPDVVARFKQRYPDGI 573
[Close]
BLAST of N6-adenosine-methyltransferase subunit vs. Ensembl Mouse
Match: Mettl3 (methyltransferase like 3 [Source:MGI Symbol;Acc:MGI:1927165])

HSP 1 Score: 171.014 bits (432), Expect = 1.056e-50
Identity = 82/118 (69.49%), Postives = 92/118 (77.97%), Query Frame = 3 
Query: 1329 IWVKTNQLQRIIRTGRTGHWINHGKEHCLVGVKGNPKGMNRGLDCDVIVSEVRETSHKPDEIYGIIERLSPGTRKLELFGRPHNLQPNWITLGNQLEGTKLVDPEVVERFRKRYPDGL 1682
            IWVKTNQLQRIIRTGRTGHW+NHGKEHCLV                      R TSHKPDEIYG+IERLSPGTRK+ELFGRPHN+QPNWITLGNQL+G  L+DP+VV RF++RYPDG+
Sbjct:    2 IWVKTNQLQRIIRTGRTGHWLNHGKEHCLV----------------------RSTSHKPDEIYGMIERLSPGTRKIELFGRPHNVQPNWITLGNQLDGIHLLDPDVVARFKQRYPDGI 97
[Close]
BLAST of N6-adenosine-methyltransferase subunit vs. Ensembl Mouse
Match: Mettl3 (methyltransferase like 3 [Source:MGI Symbol;Acc:MGI:1927165])

HSP 1 Score: 149.058 bits (375), Expect = 8.218e-40
Identity = 66/110 (60.00%), Postives = 90/110 (81.82%), Query Frame = 3 
Query:  672 IENLLGAQTAKEKETKRVNDEITYLLDRASAKEQSLIERFKSQRGSNVQQFCHYGTKEECSKVNEI---CKKLHFRKIIQAHTDESLGDCSFLNTCFHIESCKYVHYEIN 992
            IE+LL  Q+ KE+++K+V+ EI  LL+  +AKEQS++E+F+S+  + VQ+FC YGTKEEC K ++    C+KLHFR+II  HTDESLGDCSFLNTCFH+++CKYVHYEI+
Sbjct:  174 IESLLNQQSTKEQQSKKVSQEILELLNTTTAKEQSIVEKFRSRGRAQVQEFCDYGTKEECMKASDADRPCRKLHFRRIINKHTDESLGDCSFLNTCFHMDTCKYVHYEID 283
[Close]
BLAST of N6-adenosine-methyltransferase subunit vs. Ensembl Mouse
Match: Mettl3 (methyltransferase like 3 [Source:MGI Symbol;Acc:MGI:1927165])

HSP 1 Score: 111.309 bits (277), Expect = 3.782e-27
Identity = 52/92 (56.52%), Postives = 72/92 (78.26%), Query Frame = 3 
Query:  672 IENLLGAQTAKEKETKRVNDEITYLLDRASAKEQSLIERFKSQRGSNVQQFCHYGTKEECSKVNEI---CKKLHFRKIIQAHTDESLGDCSF 938
            IE+LL  Q+ KE+++K+V+ EI  LL+  +AKEQS++E+F+S+  + VQ+FC YGTKEEC K ++    C+KLHFR+II  HTDESLGDCSF
Sbjct:  154 IESLLNQQSTKEQQSKKVSQEILELLNTTTAKEQSIVEKFRSRGRAQVQEFCDYGTKEECMKASDADRPCRKLHFRRIINKHTDESLGDCSF 245
[Close]
BLAST of N6-adenosine-methyltransferase subunit vs. Ensembl Mouse
Match: Mettl3 (methyltransferase like 3 [Source:MGI Symbol;Acc:MGI:1927165])

HSP 1 Score: 102.064 bits (253), Expect = 6.900e-26
Identity = 49/59 (83.05%), Postives = 54/59 (91.53%), Query Frame = 3 
Query: 1329 IWVKTNQLQRIIRTGRTGHWINHGKEHCLVGVKGNPKGMNRGLDCDVIVSEVRETSHKP 1505
            IWVKTNQLQRIIRTGRTGHW+NHGKEHCLVGVKGNP+G N+GLDCDVIV+E  + S KP
Sbjct:    2 IWVKTNQLQRIIRTGRTGHWLNHGKEHCLVGVKGNPQGFNQGLDCDVIVAE--DYSWKP 58
[Close]
BLAST of N6-adenosine-methyltransferase subunit vs. UniProt/SwissProt
Match: sp|F1R777|MTA70_DANRE (N6-adenosine-methyltransferase subunit METTL3 OS=Danio rerio OX=7955 GN=mettl3 PE=2 SV=1)

HSP 1 Score: 525.783 bits (1353), Expect = 0.000e+0
Identity = 242/367 (65.94%), Postives = 297/367 (80.93%), Query Frame = 3 
Query:  615 AYKLENNNLIKEEFCKLENIENLLGAQTAKEKETKRVNDEITYLLDRASAKEQSLIERFKSQRGSNVQQFCHYGTKEECSKVNEI---CKKLHFRKIIQAHTDESLGDCSFLNTCFHIESCKYVHYEINQP-----DSIQEDNNGKYLGIHAR---HDTTSLYQPQWIECDIRELDMSILGKFAVIMADPPWDIHMELPYGTMSDEEMSRLDIPCLQTEGYIFLWVTGRAMEQGRECLRLWGYQCLEEIIWVKTNQLQRIIRTGRTGHWINHGKEHCLVGVKGNPKGMNRGLDCDVIVSEVRETSHKPDEIYGIIERLSPGTRKLELFGRPHNLQPNWITLGNQLEGTKLVDPEVVERFRKRYPDGL 1682
            A K   +N ++     +E IE+LL  Q+ KE+++K+V+ EI  LL+ +SAKEQS++E+F+S+  + VQ+FC YGTKEEC +  +    C KLHFR+II  HTDESLGDCSFLNTCFH+++CKYVHYEI+ P     D++        LG+H+     +   L+  QWI CDIR LD+SILGKFAV+MADPPWDIHMELPYGT++D+EM +L+IP LQ +G++FLWVTGRAME GRECL LWGY  ++EIIWVKTNQLQRIIRTGRTGHW+NHGKEHCLVGVKGNP+G NRGLDCDVIV+EVR TSHKPDEIYG+IERLSPGTRK+ELFGRPHN+QPNWITLGNQL+G  L+DPEVV RF+KRYPDG+
Sbjct:  212 ADKKGRSNKVQASHLDME-IESLLSQQSTKEQQSKKVSQEILELLNTSSAKEQSIVEKFRSRGRAQVQEFCDYGTKEECVQSGDTPQPCTKLHFRRIINKHTDESLGDCSFLNTCFHMDTCKYVHYEIDSPPEAEGDALGPQAGAAELGLHSTVGDSNVGKLFPSQWICCDIRYLDVSILGKFAVVMADPPWDIHMELPYGTLTDDEMRKLNIPILQDDGFLFLWVTGRAMELGRECLSLWGYDRVDEIIWVKTNQLQRIIRTGRTGHWLNHGKEHCLVGVKGNPQGFNRGLDCDVIVAEVRSTSHKPDEIYGMIERLSPGTRKIELFGRPHNVQPNWITLGNQLDGIHLLDPEVVARFKKRYPDGV 577
[Close]
BLAST of N6-adenosine-methyltransferase subunit vs. UniProt/SwissProt
Match: sp|Q86U44|MTA70_HUMAN (N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2)

HSP 1 Score: 522.702 bits (1345), Expect = 1.501e-179
Identity = 260/462 (56.28%), Postives = 328/462 (71.00%), Query Frame = 3 
Query:  474 VDSCLEKFSLQQFIKLK----PDEMHSTIFYVSYIDHDKISIFL---------------------EDNKDDDAYKLENNNLI-----------KEEFCKLEN---------IENLLGAQTAKEKETKRVNDEITYLLDRASAKEQSLIERFKSQRGSNVQQFCHYGTKEECSKVNEI---CKKLHFRKIIQAHTDESLGDCSFLNTCFHIESCKYVHYEINQ------PDS-----IQEDNNGKYLGIHARHDTTSLYQPQWIECDIRELDMSILGKFAVIMADPPWDIHMELPYGTMSDEEMSRLDIPCLQTEGYIFLWVTGRAMEQGRECLRLWGYQCLEEIIWVKTNQLQRIIRTGRTGHWINHGKEHCLVGVKGNPKGMNRGLDCDVIVSEVRETSHKPDEIYGIIERLSPGTRKLELFGRPHNLQPNWITLGNQLEGTKLVDPEVVERFRKRYPDGL 1682
            V+S L+KF+ Q+ I++K     D+ H T+  V+Y DH K+S  +                        +D        ++L+           KE   K            IE+LL  Q+ KE+++K+V+ EI  LL+  +AKEQS++E+F+S+  + VQ+FC YGTKEEC K ++    C+KLHFR+II  HTDESLGDCSFLNTCFH+++CKYVHYEI+       P S      QE    + +G  +  D   L+ PQWI CDIR LD+SILGKFAV+MADPPWDIHMELPYGT++D+EM RL+IP LQ +G++FLWVTGRAME GRECL LWGY+ ++EIIWVKTNQLQRIIRTGRTGHW+NHGKEHCLVGVKGNP+G N+GLDCDVIV+EVR TSHKPDEIYG+IERLSPGTRK+ELFGRPHN+QPNWITLGNQL+G  L+DP+VV RF++RYPDG+
Sbjct:  116 VESLLQKFAAQELIEVKRGLLQDDAHPTL--VTYADHSKLSAMMGAVAEKKGPGEVAGTVTGQKRRAEQDSTTVAAFASSLVSGLNSSASEPAKEPAKKSRKHAASDVDLEIESLLNQQSTKEQQSKKVSQEILELLNTTTAKEQSIVEKFRSRGRAQVQEFCDYGTKEECMKASDADRPCRKLHFRRIINKHTDESLGDCSFLNTCFHMDTCKYVHYEIDACMDSEAPGSKDHTPSQELALTQSVGGDSSAD--RLFPPQWICCDIRYLDVSILGKFAVVMADPPWDIHMELPYGTLTDDEMRRLNIPVLQDDGFLFLWVTGRAMELGRECLNLWGYERVDEIIWVKTNQLQRIIRTGRTGHWLNHGKEHCLVGVKGNPQGFNQGLDCDVIVAEVRSTSHKPDEIYGMIERLSPGTRKIELFGRPHNVQPNWITLGNQLDGIHLLDPDVVARFKQRYPDGI 573
[Close]
BLAST of N6-adenosine-methyltransferase subunit vs. UniProt/SwissProt
Match: sp|Q8C3P7|MTA70_MOUSE (N6-adenosine-methyltransferase subunit METTL3 OS=Mus musculus OX=10090 GN=Mettl3 PE=1 SV=2)

HSP 1 Score: 518.079 bits (1333), Expect = 8.194e-178
Identity = 232/349 (66.48%), Postives = 288/349 (82.52%), Query Frame = 3 
Query:  672 IENLLGAQTAKEKETKRVNDEITYLLDRASAKEQSLIERFKSQRGSNVQQFCHYGTKEECSKVNEI---CKKLHFRKIIQAHTDESLGDCSFLNTCFHIESCKYVHYEINQPDSIQEDNNGKYL---------GIHARHDTTSLYQPQWIECDIRELDMSILGKFAVIMADPPWDIHMELPYGTMSDEEMSRLDIPCLQTEGYIFLWVTGRAMEQGRECLRLWGYQCLEEIIWVKTNQLQRIIRTGRTGHWINHGKEHCLVGVKGNPKGMNRGLDCDVIVSEVRETSHKPDEIYGIIERLSPGTRKLELFGRPHNLQPNWITLGNQLEGTKLVDPEVVERFRKRYPDGL 1682
            IE+LL  Q+ KE+++K+V+ EI  LL+  +AKEQS++E+F+S+  + VQ+FC YGTKEEC K ++    C+KLHFR+II  HTDESLGDCSFLNTCFH+++CKYVHYEI+     +   + +++          +        L+ PQWI CDIR LD+SILGKFAV+MADPPWDIHMELPYGT++D+EM RL+IP LQ +G++FLWVTGRAME GRECL LWGY+ ++EIIWVKTNQLQRIIRTGRTGHW+NHGKEHCLVGVKGNP+G N+GLDCDVIV+EVR TSHKPDEIYG+IERLSPGTRK+ELFGRPHN+QPNWITLGNQL+G  L+DP+VV RF++RYPDG+
Sbjct:  225 IESLLNQQSTKEQQSKKVSQEILELLNTTTAKEQSIVEKFRSRGRAQVQEFCDYGTKEECMKASDADRPCRKLHFRRIINKHTDESLGDCSFLNTCFHMDTCKYVHYEIDACVDSESPGSKEHMPSQELALTQSVGGDSSADRLFPPQWICCDIRYLDVSILGKFAVVMADPPWDIHMELPYGTLTDDEMRRLNIPVLQDDGFLFLWVTGRAMELGRECLNLWGYERVDEIIWVKTNQLQRIIRTGRTGHWLNHGKEHCLVGVKGNPQGFNQGLDCDVIVAEVRSTSHKPDEIYGMIERLSPGTRKIELFGRPHNVQPNWITLGNQLDGIHLLDPDVVARFKQRYPDGI 573
[Close]
BLAST of N6-adenosine-methyltransferase subunit vs. UniProt/SwissProt
Match: sp|Q9VCE6|MTA70_DROME (N6-adenosine-methyltransferase MT-A70-like protein OS=Drosophila melanogaster OX=7227 GN=Mettl3 PE=1 SV=1)

HSP 1 Score: 462.611 bits (1189), Expect = 1.085e-155
Identity = 203/289 (70.24%), Postives = 242/289 (83.74%), Query Frame = 3 
Query:  834 GTKEECSKVNEICKKLHFRKIIQAHTDESLGDCSFLNTCFHIESCKYVHYEINQPDSIQEDNNGKYLGIHAR-------HDTTSLYQPQWIECDIRELDMSILGKFAVIMADPPWDIHMELPYGTMSDEEMSRLDIPCLQTEGYIFLWVTGRAMEQGRECLRLWGYQCLEEIIWVKTNQLQRIIRTGRTGHWINHGKEHCLVGVKGNPKGMNRGLDCDVIVSEVRETSHKPDEIYGIIERLSPGTRKLELFGRPHNLQPNWITLGNQLEGTKLVDPEVVERFRKRYPDG 1679
            G+    S+  + C KLHF+KIIQAHTDESLGDCSFLNTCFH+ +CKYVHYE+   D++   N  K   +  +         + +LY PQWI+CD+R LDM++LGKFAV+MADPPWDIHMELPYGTMSD+EM  L +P LQ +G IFLWVTGRAME GR+CL+LWGY+ ++E+IWVKTNQLQRIIRTGRTGHW+NHGKEHCLVG+KGNP  +NRGLDCDVIV+EVR TSHKPDEIYGIIERLSPGTRK+ELFGRPHN+QPNWITLGNQL+G +LVDPE++ +F+KRYPDG
Sbjct:  305 GSDTCSSETTDKCTKLHFKKIIQAHTDESLGDCSFLNTCFHMATCKYVHYEV---DTLPHINTNKPTDVKTKLSLKRSVDSSCTLYPPQWIQCDLRFLDMTVLGKFAVVMADPPWDIHMELPYGTMSDDEMRALGVPALQDDGLIFLWVTGRAMELGRDCLKLWGYERVDELIWVKTNQLQRIIRTGRTGHWLNHGKEHCLVGMKGNPTNLNRGLDCDVIVAEVRATSHKPDEIYGIIERLSPGTRKIELFGRPHNIQPNWITLGNQLDGIRLVDPELITQFQKRYPDG 590

HSP 2 Score: 73.559 bits (179), Expect = 2.475e-12
Identity = 78/287 (27.18%), Postives = 132/287 (45.99%), Query Frame = 3 
Query:   45 MGDTWKDIQEVKNKKTSIREKLENRKRQRENLMASVNVVPIKKHANNEVKKLSNNIYIMKHSTLKKCIEDPLTLD--NNDDLSNVVGMTECYDNILHDDKIINSNVENQMLTIISNLTTREELSNKDIHDIIVQKEPQLKLEGLIVDSCLEKFSLQQFIKLKPDEMHSTIFYVSYIDHDKISIFLEDNKDDDAYKLENNNLIKEEFC--KLENIENLLGAQTAKEKETKRVNDEITYLLDRASAKEQSLIERFKSQRGSNVQQFCHYGTKEECSKVNEICKKLHFRK 893
            M D W DI+ +K K+ ++REKLE RK++R  +++      I++   N  K+L      ++   L+      L L   +   +  + G +      L     I   + NQ   +I N+T   E   + I   +  KE +  LE    D+C +K   +   KL+ D++                    D   +   KLE+    KE       ++I  LL   + +EK++K+V +EI  LL + +AKE+S+ E+FKS  G+ V +FC +GTK EC K  +   ++  +K
Sbjct:    1 MADAW-DIKSLKTKRNTLREKLEKRKKERIEILSD-----IQEDLTNPKKELVEADLEVQKEVLQALSSCSLALPIVSTQVVEKIAGSS------LEMVNFILGKLANQGAIVIRNVTIGTEAGCEIIS--VQPKELKEILED-TNDTCQQKEE-EAKRKLEVDDV--------------------DQPQEKTIKLESTVARKESTSLDAPDDIMMLLSMPSTREKQSKQVGEEILELLTKPTAKERSVAEKFKSHGGAQVMEFCSHGTKVECLKAQQATAEMAAKK 251
[Close]
BLAST of N6-adenosine-methyltransferase subunit vs. UniProt/SwissProt
Match: sp|O82486|MTA70_ARATH (N6-adenosine-methyltransferase MT-A70-like OS=Arabidopsis thaliana OX=3702 GN=MTA PE=1 SV=2)

HSP 1 Score: 416.387 bits (1069), Expect = 1.106e-136
Identity = 196/353 (55.52%), Postives = 257/353 (72.80%), Query Frame = 3 
Query:  630 NNNLIKEEFCKLENIENLLGAQTAKEKETKRVNDEITYLLDRASAKEQSLIERFKSQRGSNVQQFCHYGTKEEC---SKVNEICKKLHFRKIIQAHTDESLGDCSFLNTCFHIESCKYVHYEINQPDSIQEDNNGKYLGIHARH-DTTSLYQPQWIECDIRELDMSILGKFAVIMADPPWDIHMELPYGTMSDEEMSRLDIPCLQTEGYIFLWVTGRAMEQGRECLRLWGYQCLEEIIWVKTNQLQRIIRTGRTGHWINHGKEHCLVGVKGNPKGMNRGLDCDVIVSEVRETSHKPDEIYGIIERLSPGTRKLELFGRPHNLQPNWITLGNQLEGTKLVDPEVVERFRKRYPD 1676
            +N  ++ E   L+++E LL  ++ KEK+  R  +E+  L+ R +AKE +   +FKS+ GS V+ +C Y TKE+C   S  +  C K HFR++I +HTD SLGDCSFL+TC H+++CKYVHYE++  D++    +     + A +     L + QWI CDIR   M ILG F V+MADPPWDIHMELPYGTM+D+EM  L++P LQT+G IFLWVTGRAME GRECL LWGY+ +EEIIWVKTNQLQRIIRTGRTGHW+NH KEHCLVG+KGNP+ +NR +D DVIV+EVRETS KPDE+Y ++ER+ P  RKLELF R HN    W++LGNQL G +L++  +  RF+  YP+
Sbjct:  306 SNQKLRSEEEDLKDVEALLSKKSFKEKQQSRTGEELLDLIHRPTAKEAATAAKFKSKGGSQVKYYCRYLTKEDCRLQSGSHIACNKRHFRRLIASHTDVSLGDCSFLDTCRHMKTCKYVHYELDMADAMMAGPDKALKPLRADYCSEAELGEAQWINCDIRSFRMDILGTFGVVMADPPWDIHMELPYGTMADDEMRTLNVPSLQTDGLIFLWVTGRAMELGRECLELWGYKRVEEIIWVKTNQLQRIIRTGRTGHWLNHSKEHCLVGIKGNPE-VNRNIDTDVIVAEVRETSRKPDEMYAMLERIMPRARKLELFARMHNAHAGWLSLGNQLNGVRLINEGLRARFKASYPE 657
[Close]
BLAST of N6-adenosine-methyltransferase subunit vs. TrEMBL
Match: A0A1S3J0D7 (N6-adenosine-methyltransferase catalytic subunit OS=Lingula unguis OX=7574 GN=LOC106169103 PE=3 SV=1)

HSP 1 Score: 563.533 bits (1451), Expect = 0.000e+0
Identity = 290/565 (51.33%), Postives = 373/565 (66.02%), Query Frame = 3 
Query:   45 MGDTWKDIQEVKNKKTSIREKLENRKRQRENLMASVNVVPIKKHANNEVKKLSNNIYIMKHSTLKKCIEDPLTLDNNDDLSNVVGMTECYDNILHDDKIINSNVENQMLTIISNLTTREELSNKDIHDIIVQKEPQLKLEGLI----VDSCLEKFSLQQFIKLKPDEMHSTI--FYVSYIDHDKISIFLE------DNKDDDAYKLEN-----NNLIKEEFCKLENIENLLGAQTAKEKETKRVNDEITYLLDRASAKEQSLIERFKSQRGSNVQQFCHYGTKEECSKVN-EICKKLHFRKIIQAHTDESLGDCSFLNTCFHIESCKYVHYEINQPDSIQEDNNGKYLGIHARHDTTSLYQPQWIECDIRELDMSILGKFAVIMADPPWDIHMELPYGTMSDEEMSRLDIPCLQTEGYIFLWVTGRAMEQGRECLRLWGYQCLEEIIWVKTNQLQRIIRTGRTGHWINHGKEHCLVGVKGNPKGMNRGLDCDVIVSEVRETSHKPDEIYGIIERLSPGTRKLELFGRPHNLQPNWITLGNQLEGTKLVDPEVVERFRKRYPDGLK 1685
            M DTW DIQ VK+K++S+REKL  R+R+RE L+  ++  P    +       +         TL    + P     +     VV  T+           +   VE Q+L  + ++       N  +  +++    +  LE  +    +D  LEKF+ QQ I +K  +  +      V  +D  K+  F          K      LEN     +   K E  K   IE+LL  Q+AKE+E K++N+EI  LL + +AKEQSL+E+FKSQ G  VQ+FC YGTKEEC +++ E CKKLHFRKII  HTDESLGDCSFLNTCFH+E+CKYVHYEI+ P+        K L      D   +  PQW+ CD+R LDM+ILGK +VIMADPPWDIHMELPYGTM+D+EM  L + CLQ +GY+FLWVTGRAME GRECL++WGY  ++E+IWVKTNQLQRIIRTGRTGHW+NHGKEHCL+GVKGNP+  NRG+DCDV+V+EVR TSHKPDEIYGIIERLSPGTRK+ELFGRPHN+QPNWITLGNQL+G +LV+P++V+R++KRYP+G K
Sbjct:    1 MSDTWSDIQAVKSKQSSLREKLMQRRREREGLLKQISGAPASNSSTLPTSDPTKGTVATSTPTLTS--QSPAVTPASATTPKVVEKTK-----------LEPEVERQVLLSLQDVGL-----NLPVESVVLCSSVEKALEKEVALSSLDDLLEKFATQQLISIKRQDASTGKEKVIVESVDLAKLGAFSAAADIHPSGKKRKRDNLENKEPRSSKQSKGEGVKDGGIESLLSMQSAKERENKKMNEEILELLTKPTAKEQSLVEKFKSQ-GVVVQEFCQYGTKEECGRLSREPCKKLHFRKIIHKHTDESLGDCSFLNTCFHMETCKYVHYEIDYPEVKTVTEGDKTLVKSPFGDAIKMTPPQWVCCDLRTLDMTILGKCSVIMADPPWDIHMELPYGTMADDEMRSLPVKCLQDDGYMFLWVTGRAMELGRECLQIWGYDRVDELIWVKTNQLQRIIRTGRTGHWLNHGKEHCLIGVKGNPQA-NRGMDCDVLVAEVRATSHKPDEIYGIIERLSPGTRKVELFGRPHNIQPNWITLGNQLDGIRLVEPDIVKRYKKRYPEGYK 545
[Close]
BLAST of N6-adenosine-methyltransferase subunit vs. TrEMBL
Match: A0A3S1BYF3 (Uncharacterized protein OS=Elysia chlorotica OX=188477 GN=EGW08_000182 PE=3 SV=1)

HSP 1 Score: 558.91 bits (1439), Expect = 0.000e+0
Identity = 294/581 (50.60%), Postives = 389/581 (66.95%), Query Frame = 3 
Query:   45 MGDTWKDIQEVKNKKTSIREKLENRKRQRENLMASV-------NVVPI----KKHANNE---VKKLSNNIYIMKHSTLKKCIED---PLTLDNNDDLSNVVGMTECYDNILHDDKIINSNVENQMLTIISNLTTREELSNKDIHD---IIVQKEPQLKLEGLIVDSCLEKFSLQQFIKLKPDEMHSTIFYVSYIDHDKISIFLEDNK----DDDAYKLENNNLIKEEFCKLE--NIENLLGAQTAKEKETKRVNDEITYLLDRASAKEQSLIERFKSQRGSNVQQFCHYGTKEECSKV---NEICKKLHFRKIIQAHTDESLGDCSFLNTCFHIESCKYVHYEINQP--DSIQ----EDNNGKYLGIHARHD-TTSLYQPQWIECDIRELDMSILGKFAVIMADPPWDIHMELPYGTMSDEEMSRLDIPCLQTEGYIFLWVTGRAMEQGRECLRLWGYQCLEEIIWVKTNQLQRIIRTGRTGHWINHGKEHCLVGVKGNPKGMNRGLDCDVIVSEVRETSHKPDEIYGIIERLSPGTRKLELFGRPHNLQPNWITLGNQLEGTKLVDPEVVERFRKRYPDG 1679
            M D W DIQ +KN+++S+R K+  R++QRE L A +       ++VP+      +AN E     + S+N        +   +E    P T++  D L                  +I+ +VE +ML ++ +++      +K I +     +++E  +K    +++  L KF++++ I +K  E    +  V+ +D  K+S      K     DD  + + N+   +     E  +IE+LL  Q+ KE+E K++N+EI  LL   +AKEQ L+E+FKS+ G  +Q+FC YGT+EEC +    +  CK+LHF+KII  HTDESLGDCSFLNTCFH+++CKYVHYEI+ P   S Q    E + GK L      D +  ++ PQWI+CD+R  DMS LGK AV+MADPPWDIHMELPYGTM D EM RL+IP LQ EG+IFLWVTGRAME GRECL LWGY+ ++EIIWVKTNQLQRIIRTGRTGHWINHGKEHCLVGVKGNPKG+NRG+DCDVIV+EVR TSHKPDEIYGIIERLSPGTRK+ELFGRPHN+QPNWITLGNQLEG +L DP++V+ FR++YPDG
Sbjct:    1 MADAWNDIQALKNRQSSMRAKMMERRKQREGLAAELTSSGAAPSIVPVTTVSSPNANAEPPTTAQQSSNPNQTPKQPVSISVEPSIKPTTIEQQDILP-----------------VIDPDVEKKMLMVLCDISLDIPSDSKVIAEHTSRFMEREVDIK----VIEDLLRKFAVEKLISIKVSETARGLI-VNSLDLTKLSAVTRGKKRRRDSDDEGEEDGNSKQSKTGGGPESGDIESLLSMQSTKEREEKKLNEEIQALLVTQTAKEQYLVEKFKSRGGPQLQEFCQYGTREECYRTGPDSANCKRLHFKKIIHKHTDESLGDCSFLNTCFHMDTCKYVHYEIDYPRLPSTQLMKKESSLGKTLSSEIGDDGSVQMFPPQWIQCDLRYFDMSTLGKCAVVMADPPWDIHMELPYGTMGDNEMRRLNIPGLQDEGFIFLWVTGRAMELGRECLELWGYKRVDEIIWVKTNQLQRIIRTGRTGHWINHGKEHCLVGVKGNPKGVNRGMDCDVIVAEVRATSHKPDEIYGIIERLSPGTRKVELFGRPHNVQPNWITLGNQLEGVRLKDPDIVKLFREKYPDG 559
[Close]
BLAST of N6-adenosine-methyltransferase subunit vs. TrEMBL
Match: A0A1B6DGV4 (Uncharacterized protein OS=Clastoptera arizonana OX=38151 GN=g.28257 PE=3 SV=1)

HSP 1 Score: 557.37 bits (1435), Expect = 0.000e+0
Identity = 291/593 (49.07%), Postives = 390/593 (65.77%), Query Frame = 3 
Query:   45 MGDTWKDIQEVKNKKTSIREKLENRKRQRENLM-----ASVNVVPIKKHANNEVKKLSNNIYIMKHSTLKKCIEDPLTLDNNDDLSNVVGMTECYDNILHDDKIINSNVENQMLTIISNLTTREELSNKDIHDIIVQKEPQLKLEGLIVDS-----CLEKFSLQQFIKLKPD-EMHSTIFYVSYIDHDK-ISIFLEDNKDDD-------------AYKLENNNLIKEEFCKLE------------------NIENLLGAQTAKEKETKRVNDEITYLLDRASAKEQSLIERFKSQRGSNVQQFCHYGTKEECSKVN-EICKKLHFRKIIQAHTDESLGDCSFLNTCFHIESCKYVHYEINQPDSI----QEDNNGKYLGIHARHDTTSLYQPQWIECDIRELDMSILGKFAVIMADPPWDIHMELPYGTMSDEEMSRLDIPCLQTEGYIFLWVTGRAMEQGRECLRLWGYQCLEEIIWVKTNQLQRIIRTGRTGHWINHGKEHCLVGVKGNPKGMNRGLDCDVIVSEVRETSHKPDEIYGIIERLSPGTRKLELFGRPHNLQPNWITLGNQLEGTKLVDPEVVERFRKRYPDG 1679
            M D W++IQ +KNK+ S+REKL+ RK++R++++     +  NV P+ K  N++         +   ST +   ED  +L +ND                      + ++E Q+L ++  L+    +++  + + + +     +L G +V S      L+KF+ QQ I +  + + +  +  V   +HDK +++  E NK+D+               K+     + E   KL                   +I +LL   + +EKE K+V +EI  LL + +AKE+SL ERF+SQ G+ V +FC +GT+ EC+KV  E CKKLHF+KIIQ HTDESLGDCSFLNTCFH++SCKYVHY+++ P         D  GK +      + T L+ PQW++CD+R LDM++LGKFAVIMADPPWDIHMELPYGTMSD+EM +L IP LQ  G IFLWVTGRAME GRECL+LWGY+ ++EIIWVKTNQLQRIIRTGRTGHW+NHGKEHCLVG+KGNP  +N+GLDCDVIV+EVR TSHKPDEIYGIIERLSPGTRK+ELFGRPHN+QPNWITLGNQ++G +LVDPE+++ FRKRYPDG
Sbjct:    1 MSDAWEEIQAIKNKRNSLREKLQKRKKERQDILSLSGGSESNVSPLGKVLNSDGGGSGVPSPVTNRSTDE--FEDTDSLPSNDLFKP------------------DPSIETQLLCVLCELSLVLPMTSSSLCNSVAK-----RLGGKLVSSETIINLLQKFATQQLISVTENFKDNKVVLEVVSAEHDKLVAMANELNKEDNLGKVFEAVTQTKSVKKIRVERELSEPPTKLAKVLTSTDKDDKKREKKTTDIMSLLSMPSIREKENKKVGEEILALLSQPTAKERSLAERFRSQGGAQVMEFCPHGTRAECAKVGAETCKKLHFKKIIQKHTDESLGDCSFLNTCFHMDSCKYVHYKVDGPTVPLPKDLSDPEGKKI---TSQEATILHPPQWVQCDLRYLDMTVLGKFAVIMADPPWDIHMELPYGTMSDDEMRQLGIPTLQDNGLIFLWVTGRAMELGRECLKLWGYERVDEIIWVKTNQLQRIIRTGRTGHWLNHGKEHCLVGMKGNPANLNKGLDCDVIVAEVRATSHKPDEIYGIIERLSPGTRKIELFGRPHNVQPNWITLGNQVDGVRLVDPELIQAFRKRYPDG 565
[Close]
BLAST of N6-adenosine-methyltransferase subunit vs. TrEMBL
Match: A0A1W4X4V1 (N6-adenosine-methyltransferase 70 kDa subunit isoform X1 OS=Agrilus planipennis OX=224129 GN=LOC108738764 PE=3 SV=1)

HSP 1 Score: 554.673 bits (1428), Expect = 0.000e+0
Identity = 284/571 (49.74%), Postives = 392/571 (68.65%), Query Frame = 3 
Query:   45 MGDTWKDIQEVKNKKTSIREKLENRKRQRENLMASVNVVPIKKHANNEVKKLSNNIYIMKHSTLKKCIEDPLTLDNNDDLSNVVGMTECYDNILHDDKIINSNVENQMLTIISNLTTREELSNKDIHDIIVQKEPQLK--LEGLIVDSCLEKFSLQQFIKLKPD-EMHSTIFYVSYIDHDKISIFLEDNKDDDAYKLENNNLIKEE---------------------FCKLENIENLLGAQTAKEKETKRVNDEITYLLDRASAKEQSLIERFKSQRGSNVQQFCHYGTKEECSKVNEI--CKKLHFRKIIQAHTDESLGDCSFLNTCFHIESCKYVHYEINQPDSIQEDNNGKYLGIHARHDTTSLYQPQWIECDIRELDMSILGKFAVIMADPPWDIHMELPYGTMSDEEMSRLDIPCLQTEGYIFLWVTGRAMEQGRECLRLWGYQCLEEIIWVKTNQLQRIIRTGRTGHWINHGKEHCLVGVKGNPKGMNRGLDCDVIVSEVRETSHKPDEIYGIIERLSPGTRKLELFGRPHNLQPNWITLGNQLEGTKLVDPEVVERFRKRYPDG 1679
            M D W++IQ +K+K+ S+RE+LE RK++R++++ S     +    N+    +S+N+     ST+ K  +D      ++D S++V               ++  +E ++L I+  +T +  +S+KD+   +   +P L   +    V + L+KF+ Q+ I +K   +  +T+  V++I+H K+++ + +   +     E +  +K +                       K  +I +LL   + KEKE+K+V +EI  LL + +AKE+SL ERF+SQ G+ V +FC +GTK EC + N I  CKKLHF+KIIQ HTDESLGDCSFLNTCFH+++CKYVHYE+++ D  +E  +           +T+LY PQW++CD+R LDM++LGKFAVIMADPPWDIHMELPYGTMSD+EM +L IP LQ EG IFLWVTGRAME GRECL+LWGY+ ++EIIWVKTNQLQRIIRTGRTGHW+NHGKEHCLVG+KGNP+ +NRGLD DVIV+EVR TSHKPDEIYG+IERLSPGTRK+ELFGR HN+QPNWITLGNQ++G +LVDP ++E F+K YPDG
Sbjct:    1 MSDAWEEIQAIKSKRNSLRERLEKRKKERQDILCSSLGSTVSSPVNS-FDNVSSNVP--SPSTVLK--DDVKFKARSEDESDLVK--------------VDPEIEKELLKILGEVTLQIPISSKDLVSCL---KPILSNSVHHGSVCNLLQKFATQKLITIKDTIKEGNTVVDVTFIEHSKVTVLINEVPLETKATTEKDEPLKRKREEENINEIEEDEEKKKKEKKDSKTTDIFSLLAMPSTKEKESKKVGEEILDLLSKPTAKERSLAERFRSQGGAQVMEFCPHGTKAECQRNNGIKQCKKLHFKKIIQKHTDESLGDCSFLNTCFHMDTCKYVHYEVDRIDQTKEMPSITPCKSVISTKSTTLYPPQWVQCDLRYLDMTVLGKFAVIMADPPWDIHMELPYGTMSDDEMRQLGIPQLQDEGLIFLWVTGRAMELGRECLKLWGYERVDEIIWVKTNQLQRIIRTGRTGHWLNHGKEHCLVGMKGNPQNLNRGLDSDVIVAEVRATSHKPDEIYGMIERLSPGTRKIELFGRTHNIQPNWITLGNQVDGIRLVDPALIENFKKMYPDG 549
[Close]
BLAST of N6-adenosine-methyltransferase subunit vs. TrEMBL
Match: A0A4E0RV52 (N6-adenosine-methyltransferase 70 kDa subunit OS=Fasciola hepatica OX=6192 GN=D915_008948 PE=3 SV=1)

HSP 1 Score: 553.903 bits (1426), Expect = 0.000e+0
Identity = 294/569 (51.67%), Postives = 369/569 (64.85%), Query Frame = 3 
Query:   72 EVKNKKTSIREKLENRKRQRENLMASVNVV-PIKKHANNEVKKLSNNIYIMKHSTLKKCIEDPLTLDNNDDLSNV---VGMTECYDNILHDDKIINSNVENQMLTIISNL----TTREELSNKDIHDIIVQKEPQLKLEGLIVDSCLEKFSLQQF-IKLKPDEMHSTIFYVSYIDHDKISIFLEDNKDDDAYKLENNNLIKEEFCKLENIENLLGAQTAKEKETKRVNDEITYLLDRASAKEQSLIERFKSQRGSNVQQFCHYGTKEECSKV------NEICKKLHFRKIIQAHTDESLGDCSFLNTCFHIESCKYVHYEIN-------------QPDSIQEDNNGKYLGIHARHDTT----SLYQPQWIECDIRELDMSILGKFAVIMADPPWDIHMELPYGTMSDEEMSRLDIPCLQTEGYIFLWVTGRAMEQGRECLRLWGYQCLEEIIWVKTNQLQRIIRTGRTGHWINHGKEHCLVGVKGNPKGMNRGLDCDVIVSEVRETSHKPDEIYGIIERLSPGTRKLELFGRPHNLQPNWITLGNQLEGTKLVDPEVVERFRKRYPDGL 1682
            E K K+ S+ E+L  +++QR+NL+A + +   +K   N  +KK++    I+  STL  C     T+D N         +  +   D + H   ++ ++  +     ++N+     +RE  S     D+       +    L  DS     S+ +F I  + +++  T   ++         F       D   L+              + +LLGAQ+++EKE+KRV +EI  LL+  S+KE+ L E+F+SQ GS VQQFC  GT+ EC+K        E C KLHFRKII  HTDESLGDCSFLNTCFH+++CKYVHY I+              P S Q+   G+        + T    +LY PQWI CDIR L+MSILGKFAVIMADPPWDIHMELPYGTMSD+EM RLDIPCLQ +GYIFLWVTGRAME GRECLRLWGYQ ++EIIWVKTNQLQR+IRTGRTGHW+NHGKEHCLVGVKG P+ +NRGLDCDVIVSEVRETSHKPDEIYG+IERLSPGTRKLELFGRPHNLQPNWITLGNQL+GT LVDP VVERF++ YP+GL
Sbjct:   11 EAKAKQDSMLERLAAKRKQRQNLLAGMTMTGTLKLWPNIPLKKVTKPSPIL--STLPGCTVSTATVDTNRAKETAQLPLKDSNQGDPVPHPTILLQTSQASDDTAAVNNVKLVTASRESPS-----DLARSSPSNVTSNRLDTDSDSAPHSICEFKIPERAEQISDTKAKIT---------FPGAQSQSDTTSLQTE------------LADLLGAQSSREKESKRVQEEILALLNTPSSKERFLSEKFRSQGGSQVQQFCAQGTRIECAKYKARTGNQERCTKLHFRKIIHPHTDESLGDCSFLNTCFHVDTCKYVHYTIDYADEETGRTMQMTHPASTQQHTTGQIQATENTQNETEAPAALYPPQWINCDIRLLNMSILGKFAVIMADPPWDIHMELPYGTMSDDEMRRLDIPCLQDDGYIFLWVTGRAMELGRECLRLWGYQRVDEIIWVKTNQLQRLIRTGRTGHWLNHGKEHCLVGVKGKPQSVNRGLDCDVIVSEVRETSHKPDEIYGLIERLSPGTRKLELFGRPHNLQPNWITLGNQLDGTYLVDPAVVERFKRHYPNGL 551
[Close]
BLAST of N6-adenosine-methyltransferase subunit vs. Ensembl Cavefish
Match: mettl3 (methyltransferase like 3 [Source:NCBI gene;Acc:103037149])

HSP 1 Score: 518.85 bits (1335), Expect = 5.929e-179
Identity = 235/348 (67.53%), Postives = 289/348 (83.05%), Query Frame = 3 
Query:  672 IENLLGAQTAKEKETKRVNDEITYLLDRASAKEQSLIERFKSQRGSNVQQFCHYGTKEECSKVNEI---CKKLHFRKIIQAHTDESLGDCSFLNTCFHIESCKYVHYEINQPDSIQEDNNGKY-----LGIHAR---HDTTSLYQPQWIECDIRELDMSILGKFAVIMADPPWDIHMELPYGTMSDEEMSRLDIPCLQTEGYIFLWVTGRAMEQGRECLRLWGYQCLEEIIWVKTNQLQRIIRTGRTGHWINHGKEHCLVGVKGNPKGMNRGLDCDVIVSEVRETSHKPDEIYGIIERLSPGTRKLELFGRPHNLQPNWITLGNQLEGTKLVDPEVVERFRKRYPDGL 1682
            IE+LL  Q+ KE+++K+V+ EI  LL+ +SA+EQS++E+F+S+  + VQ+FC +GTKEEC +  +    C KLHFR+II  HTDESLGDCSFLNTCFH+++CKYVHYEI+ P  I+    G       LG+H+     +   L+  QWI CDIR LD+SILGKFAV+MADPPWDIHMELPYGT++D+EM +L+IP LQ +G++FLWVTGRAME GRECL LWGY  ++EIIWVKTNQLQRIIRTGRTGHW+NHGKEHCLVGVKGNP+G NRGLDCDVIV+EVR TSHKPDEIYG+IERLSPGTRK+ELFGRPHN+QPNW+TLGNQL+G  L+DP+VV RF+KRYPDG+
Sbjct:  237 IESLLSQQSTKEQQSKKVSREILELLNTSSAREQSIVEKFRSRGRAQVQEFCDHGTKEECMRYGDTPQPCNKLHFRRIINKHTDESLGDCSFLNTCFHMDTCKYVHYEIDAPPEIESGTLGPQAGATELGLHSGDGDSNVGKLFPSQWICCDIRYLDVSILGKFAVVMADPPWDIHMELPYGTLTDDEMRKLNIPILQDDGFLFLWVTGRAMELGRECLSLWGYDRVDEIIWVKTNQLQRIIRTGRTGHWLNHGKEHCLVGVKGNPQGFNRGLDCDVIVAEVRSTSHKPDEIYGMIERLSPGTRKIELFGRPHNVQPNWVTLGNQLDGIHLLDPDVVARFKKRYPDGV 584
[Close]
BLAST of N6-adenosine-methyltransferase subunit vs. Ensembl Cavefish
Match: mettl14 (methyltransferase like 14 [Source:NCBI gene;Acc:404603])

HSP 1 Score: 95.5153 bits (236), Expect = 1.368e-20
Identity = 65/215 (30.23%), Postives = 102/215 (47.44%), Query Frame = 3 
Query: 1074 PQWIECDIRELDMSILG-KFAVIMADPP------------------WDIHMELPYGTMSDEEMSRLDIPCLQTEGYIFLWV-TGRAMEQGRECLRLWGYQCLEEIIWVKTNQLQR-IIRTGRTGHWINHGKEHCLVGVKGNPKG------MNRGLDCDVIVSEVRETSH--KPDEIYGIIERLSPGTRKLELFGRPHNLQPNWITLGNQLEGTKL 1631
            P +++ D    D+  L  KF VI+ +PP                  WD  M+L    +SD               ++FLW  +G  ++ GR CLR WG++  E+I W+KTN+      +T          KEHCL+G+KG  +       ++  +D D+I+++  E  +  KP EI+ IIE    G R+L LFGR   ++P W+T+G  L  +  
Sbjct:  154 PMYLQADPDTFDLRDLKCKFDVILLEPPLEEYYRESGIIATERFWNWDDIMKLEIDEISD------------LRSFVFLWCGSGEGLDLGRMCLRKWGFRRCEDICWIKTNKNNPGKTKTLDPKAVFQRTKEHCLMGIKGTVRRSLDGDFIHANVDIDLIITDEPEMGNIEKPVEIFHIIEHFCLGLRRLHLFGRDSTIRPGWLTVGPTLTNSNF 356
[Close]
BLAST of N6-adenosine-methyltransferase subunit vs. Ensembl Cavefish
Match: mettl4 (methyltransferase like 4 [Source:ZFIN;Acc:ZDB-GENE-130129-2])

HSP 1 Score: 55.8398 bits (133), Expect = 6.633e-8
Identity = 49/171 (28.65%), Postives = 79/171 (46.20%), Query Frame = 3 
Query: 1125 KFAVIMADPPWDIHM--ELPYGTMSDEEMSRLDIPCLQTEGYIFL-WVTGRA--MEQGRECLRL-WGYQCLEEIIWVKTNQLQRIIRTGRTGHWINHGKEHCLVGVKGNPKGMNRGLDCDVIVSEVRET-SHKPDEIYGIIERLSPGTRKLELFGRPHNLQPNWITLGNQL 1616
            KF +I+ DPPW+        Y  +   ++ +L +P +   G + + WVT R   +   RE L   WG + L E +WVK  +    +    + H      E  L+G +          D  +I+S      SHKP  +  +   +SP  R LE+F R  +LQP+W + GN++
Sbjct:  222 KFDLIVLDPPWENKSVKRSSYSFLPSSQLKQLPVPAVSAAGCVVVTWVTNRPRHIRFVREELYPHWGVKLLAEWLWVKVTRTGEFVFPLDSPH--KKPYEVLLLGCEIP--------DQRLIISIPSALHSHKPS-LSVLRPYISPNARCLEMFAR--SLQPDWTSWGNEV 379
[Close]
BLAST of N6-adenosine-methyltransferase subunit vs. Ensembl Sea Lamprey
Match: mettl3 (methyltransferase like 3 [Source:NCBI gene;Acc:100004398])

HSP 1 Score: 510.76 bits (1314), Expect = 3.009e-176
Identity = 267/530 (50.38%), Postives = 342/530 (64.53%), Query Frame = 3 
Query:  288 NVVGMTECYDNILHDDKIINSNVENQMLTIISNLTTREELSNKDIHDIIVQKEPQLKLEGLIVDSCLEKFSLQQFIK-------------LKPDEMHS----------TIFYVSYIDHDKI----------------SIFLEDNKDDDAYKLENNNLI-------KEEFCKLEN-IENLLGAQTAKEKETKRVNDEITYLLDRASAKEQSLIERFKSQRGSNVQQFCHYGTKEECSKV---NEICKKLHFRKIIQAHTDESLGDCSFLNTCFHIESCKYVHYEIN-------------QPDSIQEDNNGKYLGIHARHDTTS--LYQPQWIECDIRELDMSILGKFAVIMADPPWDIHMELPYGTMSDEEMSRLDIPCLQTEGYIFLWVTGRAMEQGRECLRLWGYQCLEEIIWVKTNQLQRIIRTGRTGHWINHGKEHCLVGVKGNPKGMNRGLDCDVIVSEVRETSHKPDEIYGIIERLSPGTRKLELFGRPHNLQPNWITLGNQLEGTKLVDPEVVERFRKRYPDGL 1682
              VG+ E    +L  +  ++  +E+++L  +S+L     + +  I   I Q E  +      V+S L KF+ Q+ I              L  D  HS          T   VS +  D                  SI L  +   +  K E +          K +   L+  I +LL  Q+ +E+E+K+V+ EI  LL  ++AKEQS++E+F+S+ G+ V++FC +GTK+EC      +  C KLHFR+II  HTDESLGDCSFLNTCFH+++CKYVHYEI+                   E+          R DTT+  L+  QWI CDIR LDMSILGKF+V+MADPPWDIHMELPYGT++D+EM RL+IP LQ +GYIFLWVTGRAME GRECL+LWGY+ ++E+IWVKTNQLQRIIRTGRTGHW+NHGKEHCLVG+KGN +G NRGLDCDV+V+EVR TSHKPDEIYGIIERLSPGTRK+ELFGRPHN+QPNW+TLGNQL+G  L+DPEVV RF+KRYPDG+
Sbjct:   69 GAVGVVEVTAPVL--EVRVDPRLESRLLAYLSDLALPLPVDSAAIQTAISQSESLVTRAS--VESLLHKFAAQELIAVSAGCLPDGGPCVLVTDAEHSKLSAMLGAATTSGSVSGVTSDPGGSGGVGKGDLGQDGGSSIPLVPSSSANKRKAEASEGAPPDKMNKKTQLSSLDQEIMSLLSQQSTREQESKKVSAEILQLLTASTAKEQSILEKFRSRGGAQVREFCEHGTKQECMGACGSSRPCPKLHFRRIIHKHTDESLGDCSFLNTCFHMDTCKYVHYEIDGGGLAAGGGMGGPGRRGRMEEAAAVVAVNRPRDDTTAGKLFPSQWINCDIRFLDMSILGKFSVVMADPPWDIHMELPYGTLTDDEMRRLNIPVLQDDGYIFLWVTGRAMELGRECLKLWGYERVDELIWVKTNQLQRIIRTGRTGHWLNHGKEHCLVGMKGNTEGFNRGLDCDVLVAEVRSTSHKPDEIYGIIERLSPGTRKIELFGRPHNIQPNWVTLGNQLDGIHLLDPEVVARFKKRYPDGI 594
[Close]
BLAST of N6-adenosine-methyltransferase subunit vs. Ensembl Yeast
Match: IME4 (mRNA N6-adenosine methyltransferase required for entry into meiosis; mediates N6-adenosine methylation of bulk mRNA during the induction of sporulation which includes the meiotic regulators IME1, IME2 and IME4 itself; repressed in haploids via production of antisense IME4 transcripts; transcribed in diploid cells where antisense transcription is repressed; orthologous to human METTL3 (MT-A70) [Source:SGD;Acc:S000003160])

HSP 1 Score: 288.115 bits (736), Expect = 5.234e-90
Identity = 142/285 (49.82%), Postives = 187/285 (65.61%), Query Frame = 3 
Query:  867 ICKKLHFRKIIQAHTDESLGDCSFLNTCFHIESCKYVHYEINQPDSIQEDNNGKY-----------------LGIHARHDTTSLYQPQWIECDIRELDMSILGKFAVIMADPPWDIHMELPYGTMSDEEMSRLDIPCLQTEGYIFLWVTGRAMEQGRECLRLWGYQCLEEIIWVKTNQLQRIIRTGRTGHWINHGKEHCLVGVKGNPKGMNRGLDCDVIVSEVRETSHKPDEIYGIIERLSPGT--RKLELFGRPHNLQPNWITLGNQLEGTKLVDPEVVERFRK 1664
            I  K+HF   I+  TD SLGDCS+L+TC  + +C+Y+HY    P  +QE  + +                  LG  + H        QWI CD+R+ D  +LGKF+V++ADP W+IHM LPYGT +D E+  L +  LQ EG IFLWVTGRA+E G+E L  WGY  + E+ W+KTNQL R I TGRTGHW+NH KEH LVG+KGNPK +N+ +D D+IVS  RETS KPDE+YGI ERL+ GT  RKLE+FGR HN +P W T+GNQL G  + + +V  ++++
Sbjct:  238 IQSKIHFIPNIKPQTDISLGDCSYLDTCHKLNTCRYIHYLQYIPSCLQERADRETASENKRIRSNVSIPFYTLGNCSAHCIKKALPAQWIRCDVRKFDFRVLGKFSVVIADPAWNIHMNLPYGTCNDIELLGLPLHELQDEGIIFLWVTGRAIELGKESLNNWGYNVINEVSWIKTNQLGRTIVTGRTGHWLNHSKEHLLVGLKGNPKWINKHIDVDLIVSMTRETSRKPDELYGIAERLA-GTHARKLEIFGRDHNTRPGWFTIGNQLTGNCIYEMDVERKYQE 521
[Close]
BLAST of N6-adenosine-methyltransferase subunit vs. Ensembl Nematostella
Match: EDO45957 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRI2])

HSP 1 Score: 324.324 bits (830), Expect = 1.904e-108
Identity = 151/235 (64.26%), Postives = 182/235 (77.45%), Query Frame = 3 
Query:  813 VQQFCHYGTKEEC---SKVNEICKKLHFRKIIQAHTDESLGDCSFLNTCFHIESCKYVHYEINQPDSIQ------EDNNGKYLGIHARHDTTS--LYQPQWIECDIRELDMSILGKFAVIMADPPWDIHMELPYGTMSDEEMSRLDIPCLQTEGYIFLWVTGRAMEQGRECLRLWGYQCLEEIIWVKTNQLQRIIRTGRTGHWINHGKEHCLVGVKGNPKGMNRGLDCDVIVSEV 1484
            V +FC +GT E+C    K  + CKK+HFRKI+Q HTDE+LGDCSFLNTCFH+++CKYVHYE++  D         E +  K     ++ D+    LY PQWI CD+R L M +LGKF+VIMADPPWDIHMELPYGTMSD+EM  L +P LQ  GYIFLWVTGRAME GRECL +WGY+  +E+IWVKTNQLQR+IRTGRTGHWINHGKEHCL+GVKG+  G NRG+DCDV+V+EV
Sbjct:    3 VHEFCEHGTHEDCRKNKKHGQPCKKVHFRKILQKHTDETLGDCSFLNTCFHMDTCKYVHYEVDYNDMAMKRKEEMEKDKLKDEVSSSKEDSGKIILYPPQWISCDVRSLQMDVLGKFSVIMADPPWDIHMELPYGTMSDDEMRNLSVPSLQDNGYIFLWVTGRAMELGRECLEIWGYERCDELIWVKTNQLQRLIRTGRTGHWINHGKEHCLIGVKGDTTGFNRGMDCDVLVAEV 237
[Close]
BLAST of N6-adenosine-methyltransferase subunit vs. Ensembl Nematostella
Match: EDO29398 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T3R6])

HSP 1 Score: 80.8777 bits (198), Expect = 3.541e-16
Identity = 33/38 (86.84%), Postives = 37/38 (97.37%), Query Frame = 3 
Query: 1479 EVRETSHKPDEIYGIIERLSPGTRKLELFGRPHNLQPN 1592
            +VRETSHKPDEIYG+IERLSPGTRK+ELFGR HN+QPN
Sbjct:  383 QVRETSHKPDEIYGLIERLSPGTRKIELFGRQHNVQPN 420
[Close]
BLAST of N6-adenosine-methyltransferase subunit vs. Ensembl Nematostella
Match: EDO26880 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7TAT7])

HSP 1 Score: 63.929 bits (154), Expect = 8.478e-12
Identity = 50/177 (28.25%), Postives = 83/177 (46.89%), Query Frame = 3 
Query: 1074 PQWIECDIRELDMSIL-GKFAVIMADPPWDIHMELPYGTMSD------EEMSRLDIPCLQTE-GYIFLWV-TGRAMEQGRE----------CLRLWGYQCLEEIIWVKTNQLQRIIRTGRTGHW-----INHGKEHCLVGVKGNPKGMNRGLDCDVIVSEVRETSHKPDEIYGIIER 1532
            P ++ CD+    +  L  KF VI+ DPP + +     G   +      +++ +LDI  +  +  +IFLW  +   + +GR+          CLR WG++  E+I W+KTN+       G T +        H KEHCL+G++G    + R  D D I + V       +E  G++ R
Sbjct:   11 PMYLRCDLETFALHDLDNKFDVILVDPPLEEYQRRHAGVSFNFKPWTWDDIMKLDIEEVAAQRSFIFLWCGSHEGLTEGRKVQHLKLKSDMCLRKWGFRRCEDICWIKTNKTN----PGNTKYLEPIAIFQHTKEHCLMGIRGT---VRRSTDGDFIHANVDIDLIITEECKGVVTR 180
[Close]
BLAST of N6-adenosine-methyltransferase subunit vs. Ensembl Medaka
Match: mettl3 (methyltransferase like 3 [Source:NCBI gene;Acc:101169238])

HSP 1 Score: 513.457 bits (1321), Expect = 7.554e-177
Identity = 232/347 (66.86%), Postives = 287/347 (82.71%), Query Frame = 3 
Query:  672 IENLLGAQTAKEKETKRVNDEITYLLDRASAKEQSLIERFKSQRGSNVQQFCHYGTKEECSKVNEI---CKKLHFRKIIQAHTDESLGDCSFLNTCFHIESCKYVHYEINQP----DSIQEDNNGKYLGI---HARHDTTSLYQPQWIECDIRELDMSILGKFAVIMADPPWDIHMELPYGTMSDEEMSRLDIPCLQTEGYIFLWVTGRAMEQGRECLRLWGYQCLEEIIWVKTNQLQRIIRTGRTGHWINHGKEHCLVGVKGNPKGMNRGLDCDVIVSEVRETSHKPDEIYGIIERLSPGTRKLELFGRPHNLQPNWITLGNQLEGTKLVDPEVVERFRKRYPDGL 1682
            IE+LL  Q+ KE+++K+V+ EI  LL+ ++AKEQS++E+F+S+  + VQ+FC++GTKEEC +  +    C KLHFR+II  HTDESLGDCSFLNTCFH+++CKYVHYEI+ P     S+     G  + +    A  +  +L+  QWI CDIR LD+SILGKFAV+MADPPWDIHMELPYGT++D+EM +L+IP LQ +G++FLWVTGRAME GRECL  WGY+ ++EIIWVKTNQLQRIIRTGRTGHW+NHGKEHCLVGVKGN +G NRGLDCDVIV+EVR TSHKPDEIYG+IERLSPGTRK+ELFGRPHN+QPNWITLGNQL+G  L+DPEVV RF+ RYPDG+
Sbjct:  234 IESLLNQQSTKEQQSKKVSREILELLNASTAKEQSIVEKFRSRGRAQVQEFCNHGTKEECVRSGDAPQPCTKLHFRRIINKHTDESLGDCSFLNTCFHMDTCKYVHYEIDSPPEAESSLGPQTGGAEVSLCAGDADSNVGTLFPSQWICCDIRYLDVSILGKFAVVMADPPWDIHMELPYGTLTDDEMRKLNIPALQDDGFLFLWVTGRAMELGRECLSQWGYERVDEIIWVKTNQLQRIIRTGRTGHWLNHGKEHCLVGVKGNTQGFNRGLDCDVIVAEVRSTSHKPDEIYGMIERLSPGTRKIELFGRPHNVQPNWITLGNQLDGIHLLDPEVVARFKSRYPDGV 580
[Close]
BLAST of N6-adenosine-methyltransferase subunit vs. Ensembl Medaka
Match: mettl14 (methyltransferase like 14 [Source:NCBI gene;Acc:101170004])

HSP 1 Score: 99.7525 bits (247), Expect = 5.033e-22
Identity = 74/243 (30.45%), Postives = 116/243 (47.74%), Query Frame = 3 
Query: 1074 PQWIECDIRELDMSIL-GKFAVIMADPPWDIHMELPYGTMSDEEMSRLDIPCLQTE------GYIFLWV-TGRAMEQGRECLRLWGYQCLEEIIWVKTNQLQRIIRTGRTGHW-----INHGKEHCLVGVKGNPKGMNRG------LDCDVIVSEVRETSH--KPDEIYGIIERLSPGTRKLELFGRPHNLQPNWITLGNQLEGTKLVDPEV------------------VERFRKRYPDGLK 1685
            P +++ D    D+  L  +F VI+ +PP + +      + ++   +  DI  L+ E       ++FLW  +G  ++ GR CLR WG++  E+I W+KTN+       G+T            KEHCL+G+KG  +    G      +D D+I++E  E  +  KP EI+ IIE    G R+L LFGR   ++P W+T+G  L  T   +PE                   +ER R + P  LK
Sbjct:  134 PMYLQADPEHFDLRELKSQFDVILLEPPLEEYYRESGISHTERFWTWDDIMRLEIEEISDLRSFVFLWCGSGEGLDLGRMCLRKWGFRRCEDICWIKTNKNN----PGKTKALDPKAVFQRTKEHCLMGIKGTVRRSTDGDFIHANVDIDLIITEEPEMGNVEKPVEIFHIIEHFCLGRRRLHLFGRDSTIRPGWLTVGPNLTNTNF-NPETYASHFASPDSYLSGCTEEIERLRPKSPVKLK 371
[Close]
BLAST of N6-adenosine-methyltransferase subunit vs. Ensembl Medaka
Match: mettl14 (methyltransferase like 14 [Source:NCBI gene;Acc:101170004])

HSP 1 Score: 99.7525 bits (247), Expect = 5.374e-22
Identity = 74/243 (30.45%), Postives = 116/243 (47.74%), Query Frame = 3 
Query: 1074 PQWIECDIRELDMSIL-GKFAVIMADPPWDIHMELPYGTMSDEEMSRLDIPCLQTE------GYIFLWV-TGRAMEQGRECLRLWGYQCLEEIIWVKTNQLQRIIRTGRTGHW-----INHGKEHCLVGVKGNPKGMNRG------LDCDVIVSEVRETSH--KPDEIYGIIERLSPGTRKLELFGRPHNLQPNWITLGNQLEGTKLVDPEV------------------VERFRKRYPDGLK 1685
            P +++ D    D+  L  +F VI+ +PP + +      + ++   +  DI  L+ E       ++FLW  +G  ++ GR CLR WG++  E+I W+KTN+       G+T            KEHCL+G+KG  +    G      +D D+I++E  E  +  KP EI+ IIE    G R+L LFGR   ++P W+T+G  L  T   +PE                   +ER R + P  LK
Sbjct:  166 PMYLQADPEHFDLRELKSQFDVILLEPPLEEYYRESGISHTERFWTWDDIMRLEIEEISDLRSFVFLWCGSGEGLDLGRMCLRKWGFRRCEDICWIKTNKNN----PGKTKALDPKAVFQRTKEHCLMGIKGTVRRSTDGDFIHANVDIDLIITEEPEMGNVEKPVEIFHIIEHFCLGRRRLHLFGRDSTIRPGWLTVGPNLTNTNF-NPETYASHFASPDSYLSGCTEEIERLRPKSPVKLK 403
[Close]
BLAST of N6-adenosine-methyltransferase subunit vs. Ensembl Medaka
Match: mettl4 (methyltransferase like 4 [Source:NCBI gene;Acc:101158563])

HSP 1 Score: 59.6918 bits (143), Expect = 3.552e-9
Identity = 52/180 (28.89%), Postives = 76/180 (42.22%), Query Frame = 3 
Query: 1125 KFAVIMADPPWD---IHMELPYGTMSDEEMSRLDIPCLQTEG-YIFLWVTGRAMEQGRECLRL---WGYQCLEEIIWVKTNQLQRIIRTGRTGHWINHGKEHCLVGVKGNPKG------MNRGL--DCDVIVSEVRET-SHKPDEIYGIIERLSPGTRKLELFGRPHNLQPNWITLGNQL 1616
            KF +I+ DPPW+   +     YG++   ++ RL IP   +    +  WVT R       C  L   W  Q + +  WVK   L + +    + H         LV  + +P        M   L  D  +IVS      SHKP     +   + PG   LELF R  +LQP W + GN++
Sbjct:  191 KFDLIVMDPPWENKSVKRSRRYGSLPSSQLKRLPIPQFTSPNCLVVTWVTNRPSHLRFVCDELYPYWNVQVVAKWFWVKVTTLGQFVFPLDSQH---KKPYETLVLGRYHPSAPPSTSEMKEVLLEDSRLIVSVPSALHSHKPSLSEVLKPYIRPGAECLELFAR--SLQPGWTSWGNEV 365
[Close]
BLAST of N6-adenosine-methyltransferase subunit vs. Planmine SMEST
Match: SMESG000034548.1 (SMESG000034548.1)

HSP 1 Score: 1141.72 bits (2952), Expect = 0.000e+0
Identity = 552/552 (100.00%), Postives = 552/552 (100.00%), Query Frame = 3 
Query:   45 MGDTWKDIQEVKNKKTSIREKLENRKRQRENLMASVNVVPIKKHANNEVKKLSNNIYIMKHSTLKKCIEDPLTLDNNDDLSNVVGMTECYDNILHDDKIINSNVENQMLTIISNLTTREELSNKDIHDIIVQKEPQLKLEGLIVDSCLEKFSLQQFIKLKPDEMHSTIFYVSYIDHDKISIFLEDNKDDDAYKLENNNLIKEEFCKLENIENLLGAQTAKEKETKRVNDEITYLLDRASAKEQSLIERFKSQRGSNVQQFCHYGTKEECSKVNEICKKLHFRKIIQAHTDESLGDCSFLNTCFHIESCKYVHYEINQPDSIQEDNNGKYLGIHARHDTTSLYQPQWIECDIRELDMSILGKFAVIMADPPWDIHMELPYGTMSDEEMSRLDIPCLQTEGYIFLWVTGRAMEQGRECLRLWGYQCLEEIIWVKTNQLQRIIRTGRTGHWINHGKEHCLVGVKGNPKGMNRGLDCDVIVSEVRETSHKPDEIYGIIERLSPGTRKLELFGRPHNLQPNWITLGNQLEGTKLVDPEVVERFRKRYPDGLKRVKTS 1700
            MGDTWKDIQEVKNKKTSIREKLENRKRQRENLMASVNVVPIKKHANNEVKKLSNNIYIMKHSTLKKCIEDPLTLDNNDDLSNVVGMTECYDNILHDDKIINSNVENQMLTIISNLTTREELSNKDIHDIIVQKEPQLKLEGLIVDSCLEKFSLQQFIKLKPDEMHSTIFYVSYIDHDKISIFLEDNKDDDAYKLENNNLIKEEFCKLENIENLLGAQTAKEKETKRVNDEITYLLDRASAKEQSLIERFKSQRGSNVQQFCHYGTKEECSKVNEICKKLHFRKIIQAHTDESLGDCSFLNTCFHIESCKYVHYEINQPDSIQEDNNGKYLGIHARHDTTSLYQPQWIECDIRELDMSILGKFAVIMADPPWDIHMELPYGTMSDEEMSRLDIPCLQTEGYIFLWVTGRAMEQGRECLRLWGYQCLEEIIWVKTNQLQRIIRTGRTGHWINHGKEHCLVGVKGNPKGMNRGLDCDVIVSEVRETSHKPDEIYGIIERLSPGTRKLELFGRPHNLQPNWITLGNQLEGTKLVDPEVVERFRKRYPDGLKRVKTS
Sbjct:    1 MGDTWKDIQEVKNKKTSIREKLENRKRQRENLMASVNVVPIKKHANNEVKKLSNNIYIMKHSTLKKCIEDPLTLDNNDDLSNVVGMTECYDNILHDDKIINSNVENQMLTIISNLTTREELSNKDIHDIIVQKEPQLKLEGLIVDSCLEKFSLQQFIKLKPDEMHSTIFYVSYIDHDKISIFLEDNKDDDAYKLENNNLIKEEFCKLENIENLLGAQTAKEKETKRVNDEITYLLDRASAKEQSLIERFKSQRGSNVQQFCHYGTKEECSKVNEICKKLHFRKIIQAHTDESLGDCSFLNTCFHIESCKYVHYEINQPDSIQEDNNGKYLGIHARHDTTSLYQPQWIECDIRELDMSILGKFAVIMADPPWDIHMELPYGTMSDEEMSRLDIPCLQTEGYIFLWVTGRAMEQGRECLRLWGYQCLEEIIWVKTNQLQRIIRTGRTGHWINHGKEHCLVGVKGNPKGMNRGLDCDVIVSEVRETSHKPDEIYGIIERLSPGTRKLELFGRPHNLQPNWITLGNQLEGTKLVDPEVVERFRKRYPDGLKRVKTS 552
[Close]
BLAST of N6-adenosine-methyltransferase subunit vs. Planmine SMEST
Match: SMESG000034548.1 (SMESG000034548.1)

HSP 1 Score: 1120.53 bits (2897), Expect = 0.000e+0
Identity = 544/552 (98.55%), Postives = 544/552 (98.55%), Query Frame = 3 
Query:   45 MGDTWKDIQEVKNKKTSIREKLENRKRQRENLMASVNVVPIKKHANNEVKKLSNNIYIMKHSTLKKCIEDPLTLDNNDDLSNVVGMTECYDNILHDDKIINSNVENQMLTIISNLTTREELSNKDIHDIIVQKEPQLKLEGLIVDSCLEKFSLQQFIKLKPDEMHSTIFYVSYIDHDKISIFLEDNKDDDAYKLENNNLIKEEFCKLENIENLLGAQTAKEKETKRVNDEITYLLDRASAKEQSLIERFKSQRGSNVQQFCHYGTKEECSKVNEICKKLHFRKIIQAHTDESLGDCSFLNTCFHIESCKYVHYEINQPDSIQEDNNGKYLGIHARHDTTSLYQPQWIECDIRELDMSILGKFAVIMADPPWDIHMELPYGTMSDEEMSRLDIPCLQTEGYIFLWVTGRAMEQGRECLRLWGYQCLEEIIWVKTNQLQRIIRTGRTGHWINHGKEHCLVGVKGNPKGMNRGLDCDVIVSEVRETSHKPDEIYGIIERLSPGTRKLELFGRPHNLQPNWITLGNQLEGTKLVDPEVVERFRKRYPDGLKRVKTS 1700
            MGDTWKDIQEVKNKKTSIREKLENRKRQRENLMASVNVVPIKKHANNEVKKLSNNIYIMKHSTLKKCIEDPLTLDNNDDLSNVVGMTECYDNILHDDKIINSNVENQMLTIISNLTTREELSNKDIHDIIVQKEPQLKLEGLIVDSCLEKFSLQQFIKLKPDEMHSTIFYVSYIDHDKISIFLEDNKDDDAYK        EEFCKLENIENLLGAQTAKEKETKRVNDEITYLLDRASAKEQSLIERFKSQRGSNVQQFCHYGTKEECSKVNEICKKLHFRKIIQAHTDESLGDCSFLNTCFHIESCKYVHYEINQPDSIQEDNNGKYLGIHARHDTTSLYQPQWIECDIRELDMSILGKFAVIMADPPWDIHMELPYGTMSDEEMSRLDIPCLQTEGYIFLWVTGRAMEQGRECLRLWGYQCLEEIIWVKTNQLQRIIRTGRTGHWINHGKEHCLVGVKGNPKGMNRGLDCDVIVSEVRETSHKPDEIYGIIERLSPGTRKLELFGRPHNLQPNWITLGNQLEGTKLVDPEVVERFRKRYPDGLKRVKTS
Sbjct:    1 MGDTWKDIQEVKNKKTSIREKLENRKRQRENLMASVNVVPIKKHANNEVKKLSNNIYIMKHSTLKKCIEDPLTLDNNDDLSNVVGMTECYDNILHDDKIINSNVENQMLTIISNLTTREELSNKDIHDIIVQKEPQLKLEGLIVDSCLEKFSLQQFIKLKPDEMHSTIFYVSYIDHDKISIFLEDNKDDDAYK--------EEFCKLENIENLLGAQTAKEKETKRVNDEITYLLDRASAKEQSLIERFKSQRGSNVQQFCHYGTKEECSKVNEICKKLHFRKIIQAHTDESLGDCSFLNTCFHIESCKYVHYEINQPDSIQEDNNGKYLGIHARHDTTSLYQPQWIECDIRELDMSILGKFAVIMADPPWDIHMELPYGTMSDEEMSRLDIPCLQTEGYIFLWVTGRAMEQGRECLRLWGYQCLEEIIWVKTNQLQRIIRTGRTGHWINHGKEHCLVGVKGNPKGMNRGLDCDVIVSEVRETSHKPDEIYGIIERLSPGTRKLELFGRPHNLQPNWITLGNQLEGTKLVDPEVVERFRKRYPDGLKRVKTS 544
[Close]
BLAST of N6-adenosine-methyltransferase subunit vs. Planmine SMEST
Match: SMESG000073528.1 (SMESG000073528.1)

HSP 1 Score: 104.375 bits (259), Expect = 2.193e-23
Identity = 74/243 (30.45%), Postives = 120/243 (49.38%), Query Frame = 3 
Query: 1074 PQWIECDIRELDMSILG-KFAVIMADPPWDIHMELPYGTMSDEEMSRLDIPCLQTE------GYIFLWV-TGRAMEQGRECLRLWGYQCLEEIIWVKTNQLQRIIRTGRTGHWINHGKEHCLVGVKGNPKGMNRG------LDCDVIVSEVRE--TSHKPDEIYGIIERLSPGTRKLELFGRPHNLQPNWITLGNQ------------------LEGTKLVDPEVVERFRKRYPDGLKRVKTS 1700
            P +++ D+    ++ L  KF V++ +PP + +  +  G + D+  S  +I  L+ E       +I+LW  +G  + +GR+CL  WG++  E+I W+KTN+ +   +    G      KEHCL+G+KG  +    G      +D D+I+ E  +     KP EI+ IIE    G R+L LFGR   ++  W+TLG++                  L GT +   E +ER R + P    R KTS
Sbjct:  159 PMYLKSDLSAFKLTDLQCKFDVLLIEPPLEEYNRM-NGAVYDKYWSWSEIEALEIEQIAAQRSFIWLWCGSGEGLNEGRKCLSKWGFRRCEDICWIKTNKKKPGHKNLEPGALFQRTKEHCLMGIKGTVRRSTDGDFIHANVDIDLIIDEEPKYGIKDKPVEIFHIIEHFCLGKRRLHLFGRDSTIRQGWLTLGSELTSSNFDSRIYNNFFTKDLNGTTVPYNEEIERLRPKSPP--PRQKTS 398
The following BLAST results are available for this feature:
BLAST of N6-adenosine-methyltransferase subunit vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 4
Match NameE-valueIdentityDescription
METTL33.125e-18056.28methyltransferase like 3 [Source:HGNC Symbol;Acc:H... [more]
METTL32.457e-4140.54methyltransferase like 3 [Source:HGNC Symbol;Acc:H... [more]
METTL144.166e-2334.34methyltransferase like 14 [Source:HGNC Symbol;Acc:... [more]
METTL142.287e-635.87methyltransferase like 14 [Source:HGNC Symbol;Acc:... [more]
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BLAST of N6-adenosine-methyltransferase subunit vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of N6-adenosine-methyltransferase subunit vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 2
Match NameE-valueIdentityDescription
Mettl31.082e-15670.24gene:FBgn0039139 transcript:FBtr0084532[more]
Mettl141.498e-2131.36gene:FBgn0032016 transcript:FBtr0079599[more]
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BLAST of N6-adenosine-methyltransferase subunit vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 4
Match NameE-valueIdentityDescription
mettl30.000e+065.94methyltransferase like 3 [Source:NCBI gene;Acc:100... [more]
mettl142.943e-2131.86methyltransferase like 14 [Source:NCBI gene;Acc:40... [more]
mettl142.943e-2131.86methyltransferase like 14 [Source:NCBI gene;Acc:40... [more]
mettl48.421e-725.82methyltransferase like 4 [Source:ZFIN;Acc:ZDB-GENE... [more]
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BLAST of N6-adenosine-methyltransferase subunit vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
kdm1b2.960e-17766.00lysine (K)-specific demethylase 1B [Source:Xenbase... [more]
kdm1b7.971e-16166.04lysine (K)-specific demethylase 1B [Source:Xenbase... [more]
gbx17.910e-2231.86gastrulation brain homeobox 1 [Source:Xenbase;Acc:... [more]
gbx19.591e-2231.86gastrulation brain homeobox 1 [Source:Xenbase;Acc:... [more]
grid18.139e-726.56glutamate receptor, ionotropic, delta 1 [Source:Xe... [more]
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BLAST of N6-adenosine-methyltransferase subunit vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Mettl31.440e-17866.48methyltransferase like 3 [Source:MGI Symbol;Acc:MG... [more]
Mettl31.056e-5069.49methyltransferase like 3 [Source:MGI Symbol;Acc:MG... [more]
Mettl38.218e-4060.00methyltransferase like 3 [Source:MGI Symbol;Acc:MG... [more]
Mettl33.782e-2756.52methyltransferase like 3 [Source:MGI Symbol;Acc:MG... [more]
Mettl36.900e-2683.05methyltransferase like 3 [Source:MGI Symbol;Acc:MG... [more]
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BLAST of N6-adenosine-methyltransferase subunit vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|F1R777|MTA70_DANRE0.000e+065.94N6-adenosine-methyltransferase subunit METTL3 OS=D... [more]
sp|Q86U44|MTA70_HUMAN1.501e-17956.28N6-adenosine-methyltransferase catalytic subunit O... [more]
sp|Q8C3P7|MTA70_MOUSE8.194e-17866.48N6-adenosine-methyltransferase subunit METTL3 OS=M... [more]
sp|Q9VCE6|MTA70_DROME1.085e-15570.24N6-adenosine-methyltransferase MT-A70-like protein... [more]
sp|O82486|MTA70_ARATH1.106e-13655.52N6-adenosine-methyltransferase MT-A70-like OS=Arab... [more]
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BLAST of N6-adenosine-methyltransferase subunit vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1S3J0D70.000e+051.33N6-adenosine-methyltransferase catalytic subunit O... [more]
A0A3S1BYF30.000e+050.60Uncharacterized protein OS=Elysia chlorotica OX=18... [more]
A0A1B6DGV40.000e+049.07Uncharacterized protein OS=Clastoptera arizonana O... [more]
A0A1W4X4V10.000e+049.74N6-adenosine-methyltransferase 70 kDa subunit isof... [more]
A0A4E0RV520.000e+051.67N6-adenosine-methyltransferase 70 kDa subunit OS=F... [more]
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BLAST of N6-adenosine-methyltransferase subunit vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 3
Match NameE-valueIdentityDescription
mettl35.929e-17967.53methyltransferase like 3 [Source:NCBI gene;Acc:103... [more]
mettl141.368e-2030.23methyltransferase like 14 [Source:NCBI gene;Acc:40... [more]
mettl46.633e-828.65methyltransferase like 4 [Source:ZFIN;Acc:ZDB-GENE... [more]
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BLAST of N6-adenosine-methyltransferase subunit vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
mettl33.009e-17650.38methyltransferase like 3 [Source:NCBI gene;Acc:100... [more]
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BLAST of N6-adenosine-methyltransferase subunit vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
IME45.234e-9049.82mRNA N6-adenosine methyltransferase required for e... [more]
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BLAST of N6-adenosine-methyltransferase subunit vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 3
Match NameE-valueIdentityDescription
EDO459571.904e-10864.26Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO293983.541e-1686.84Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO268808.478e-1228.25Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of N6-adenosine-methyltransferase subunit vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 4
Match NameE-valueIdentityDescription
mettl37.554e-17766.86methyltransferase like 3 [Source:NCBI gene;Acc:101... [more]
mettl145.033e-2230.45methyltransferase like 14 [Source:NCBI gene;Acc:10... [more]
mettl145.374e-2230.45methyltransferase like 14 [Source:NCBI gene;Acc:10... [more]
mettl43.552e-928.89methyltransferase like 4 [Source:NCBI gene;Acc:101... [more]
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BLAST of N6-adenosine-methyltransferase subunit vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 3
Match NameE-valueIdentityDescription
SMESG000034548.10.000e+0100.00SMESG000034548.1[more]
SMESG000034548.10.000e+098.55SMESG000034548.1[more]
SMESG000073528.12.193e-2330.45SMESG000073528.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30020264 ID=SMED30020264|Name=N6-adenosine-methyltransferase subunit|organism=Schmidtea mediterranea sexual|type=transcript|length=1743bp
GTGTAATTTTAGCATTTCTATAATTTCAAATCTCAATTAAATTAATGGGC
GATACTTGGAAAGATATTCAAGAAGTAAAAAATAAGAAAACATCCATTAG
AGAAAAATTAGAAAATAGGAAACGTCAACGAGAAAATTTAATGGCCAGTG
TTAATGTTGTACCAATTAAAAAACACGCGAATAATGAAGTGAAAAAGTTA
TCGAATAATATATATATAATGAAACACTCAACACTTAAAAAATGTATTGA
AGATCCATTAACTCTAGATAACAACGATGATTTATCTAATGTAGTGGGCA
TGACCGAATGCTATGATAATATTTTACACGATGATAAAATTATCAATAGT
AATGTAGAAAATCAGATGTTAACTATTATTTCGAATTTAACCACTCGTGA
AGAGCTGTCAAATAAAGATATTCATGATATTATTGTACAGAAGGAGCCTC
AACTCAAATTGGAAGGTTTGATAGTTGATTCTTGTTTGGAAAAATTTAGT
TTACAACAATTCATAAAATTGAAACCAGACGAAATGCATTCAACAATTTT
TTATGTTTCATACATTGATCATGATAAAATATCAATTTTCCTTGAGGATA
ACAAAGACGATGATGCCTATAAGTTAGAAAATAATAATTTAATAAAAGAA
GAATTCTGTAAATTAGAAAATATTGAGAATTTATTAGGCGCACAAACAGC
TAAAGAAAAAGAGACAAAACGTGTCAATGATGAAATAACTTATTTATTGG
ATCGAGCTTCTGCTAAAGAACAGTCCTTAATTGAAAGGTTTAAATCTCAA
CGAGGAAGTAATGTTCAACAGTTTTGTCACTATGGTACCAAAGAAGAATG
TTCTAAAGTTAATGAAATCTGTAAAAAACTCCATTTCAGAAAGATCATCC
AAGCTCACACAGATGAATCCTTAGGCGATTGTTCATTTCTCAATACTTGC
TTTCATATAGAAAGTTGTAAATATGTACATTACGAAATTAACCAACCAGA
TAGCATCCAAGAAGATAATAATGGTAAATATTTAGGAATTCATGCAAGGC
ATGATACAACAAGTCTCTATCAGCCACAGTGGATAGAATGTGATATCAGA
GAATTAGACATGTCAATCTTAGGTAAGTTTGCAGTGATTATGGCAGATCC
TCCATGGGATATACATATGGAATTACCGTATGGCACCATGAGTGATGAAG
AAATGAGCAGGCTCGACATACCATGCTTGCAAACAGAAGGTTACATTTTT
CTTTGGGTAACTGGAAGAGCAATGGAGCAAGGACGTGAATGTTTACGTTT
ATGGGGTTATCAATGTCTCGAGGAAATCATTTGGGTGAAAACAAATCAAT
TACAGAGAATAATCCGTACAGGAAGAACTGGACATTGGATAAATCATGGA
AAAGAACATTGTTTGGTTGGAGTTAAAGGAAATCCTAAAGGAATGAATAG
AGGATTGGATTGCGATGTTATCGTGTCTGAGGTTCGAGAAACTAGTCATA
AACCAGATGAAATCTATGGAATAATTGAAAGGTTATCCCCAGGAACTAGG
AAATTGGAATTGTTTGGACGCCCACACAATCTTCAGCCCAACTGGATCAC
ATTGGGTAATCAATTAGAAGGTACTAAATTGGTAGATCCAGAAGTTGTTG
AAAGATTCAGAAAACGATATCCTGACGGTTTAAAGCGAGTAAAAACATCA
TAAAATATAAATTTGTTTTAATAAATCATTTTCATATTTTTAC
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protein sequence of SMED30020264-orf-1

>SMED30020264-orf-1 ID=SMED30020264-orf-1|Name=SMED30020264-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=553bp
MGDTWKDIQEVKNKKTSIREKLENRKRQRENLMASVNVVPIKKHANNEVK
KLSNNIYIMKHSTLKKCIEDPLTLDNNDDLSNVVGMTECYDNILHDDKII
NSNVENQMLTIISNLTTREELSNKDIHDIIVQKEPQLKLEGLIVDSCLEK
FSLQQFIKLKPDEMHSTIFYVSYIDHDKISIFLEDNKDDDAYKLENNNLI
KEEFCKLENIENLLGAQTAKEKETKRVNDEITYLLDRASAKEQSLIERFK
SQRGSNVQQFCHYGTKEECSKVNEICKKLHFRKIIQAHTDESLGDCSFLN
TCFHIESCKYVHYEINQPDSIQEDNNGKYLGIHARHDTTSLYQPQWIECD
IRELDMSILGKFAVIMADPPWDIHMELPYGTMSDEEMSRLDIPCLQTEGY
IFLWVTGRAMEQGRECLRLWGYQCLEEIIWVKTNQLQRIIRTGRTGHWIN
HGKEHCLVGVKGNPKGMNRGLDCDVIVSEVRETSHKPDEIYGIIERLSPG
TRKLELFGRPHNLQPNWITLGNQLEGTKLVDPEVVERFRKRYPDGLKRVK
TS*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0002111X2 cell
Vocabulary: INTERPRO
TermDefinition
IPR007757MT-A70-like
IPR029063SAM-dependent_MTases
IPR025848MT-A70
Vocabulary: molecular function
TermDefinition
GO:0008168methyltransferase activity
GO:0016422mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity
GO:0016740transferase activity
Vocabulary: biological process
TermDefinition
GO:0006139nucleobase-containing compound metabolic process
GO:0001510RNA methylation
GO:0032259methylation
GO:0080009mRNA methylation
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 8..28
NoneNo IPR availablePANTHERPTHR12829:SF2N6-ADENOSINE-METHYLTRANSFERASE CATALYTIC SUBUNITcoord: 6..545
NoneNo IPR availablePANTHERPTHR12829N6-ADENOSINE-METHYLTRANSFERASEcoord: 6..545
IPR007757MT-A70-likePFAMPF05063MT-A70coord: 362..523
e-value: 3.7E-60
score: 202.8
IPR007757MT-A70-likePROSITEPS51143MT_A70coord: 324..543
score: 47.409
IPR025848N6-adenosine-methyltransferase MT-A70-likePROSITEPS51563SAM_MTA70L_1coord: 1..552
score: 163.088
IPR029063S-adenosyl-L-methionine-dependent methyltransferaseSUPERFAMILYSSF53335S-adenosyl-L-methionine-dependent methyltransferasescoord: 339..508