Annexin

Overview
NameAnnexin
Smed IDSMED30020215
Length (bp)1235
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Annexin (SMED30020215) t-SNE clustered cells

Violin plots show distribution of expression levels for Annexin (SMED30020215) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Annexin (SMED30020215) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Annexin (SMED30020215) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30020215

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 11

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
pharynxSMED30020215h1SMcG0007255 dd_Smed_v4_1735_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
protonephridiaSMED30020215h1SMcG0007255 dd_Smed_v4_1735_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30020215h1SMcG0007255 dd_Smed_v4_1735_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30020215h1SMcG0007255 dd_Smed_v4_1735_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30020215h1SMcG0007255 dd_Smed_v4_1735_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymaSMED30020215h1SMcG0007255 dd_Smed_v4_1735_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30020215h1SMcG0007255 dd_Smed_v4_1735_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30020215h1SMcG0007255 Contig48696newmark_estsPMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30020215h1SMcG0007255 Contig48696uc_Smed_v2PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
head regionSMED30020215h1SMcG0007255 dd_Smed_v6_1735_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017
whole organism asexual adult RNA-sequencing evidence
epidermisSMED30020215h1SMcG0007255 dd_Smed_v4_1735_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017
whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Annexin vs. Ensembl Human
Match: ANXA7 (annexin A7 [Source:HGNC Symbol;Acc:HGNC:545])

HSP 1 Score: 294.278 bits (752), Expect = 5.514e-95
Identity = 152/325 (46.77%), Postives = 214/325 (65.85%), Query Frame = 1
Query:  160 KGTIKPFPNFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDLDYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFV 1134
            +GTI+P  NF+   D E+LRKAMKG GTDE+AI++ +  R   QR +IK  +KT +GKDLI+ LKSE+SGN ++ ++       YYDA+SL +AM+GAGT+E VL EIL +R+N +I  I   Y+  F  DLE+DI  +TSG F+R+LVS  Q N+ E  N+ I            N   A+++A  LY AGE ++GTDE+ F  I   R+  QLRAT + Y ++A +D+  S+  E SG ++S LK I   A+N+P +FA +LY +MKGAGT+D+TLVR+++TRSEIDL+ IK+ F + +  TL   +  DTSGDYR  L+  V
Sbjct:  154 QGTIRPAANFDAIRDAEILRKAMKGFGTDEQAIVDVVANRSNDQRQKIKAAFKTSYGKDLIKDLKSELSGNMEELILALFMPPTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIREIVRCYQSEFGRDLEKDIRSDTSGHFERLLVSMCQGNRDE--NQSI------------NHQMAQEDAQRLYQAGEGRLGTDESCFNMILATRSFPQLRATMEAYSRMANRDLLSSVSREFSGYVESGLKTILQCALNRPAFFAERLYYAMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFAQMYQKTLGTMIAGDTSGDYRRLLLAIV 464          

HSP 2 Score: 78.1814 bits (191), Expect = 5.443e-15
Identity = 51/196 (26.02%), Postives = 92/196 (46.94%), Query Frame = 1
Query:  568 IKETSGFFKRVLVSCLQANKPELTNEQ--IREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN*D 1149
            +    GF    + S     +P   ++   + +V +  I    N +  R    E+     K  GTDE   + +   R+  Q +     ++   GKD+   + SE+SG+++ ++ A+        +Y A  L K+M+GAGT +  L+ +L TR+  ++  I + +Q EF   LE  ++ DTSG +   L+   +GN D
Sbjct:  120 VPLPGGFPGGQMPSQYPGGQPTYPSQPATVTQVTQGTIRPAANFDAIRD--AEILRKAMKGFGTDEQAIVDVVANRSNDQRQKIKAAFKTSYGKDLIKDLKSELSGNMEELILALFMPPT---YYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIREIVRCYQSEFGRDLEKDIRSDTSGHFERLLVSMCQGNRD 310          
BLAST of Annexin vs. Ensembl Human
Match: ANXA7 (annexin A7 [Source:HGNC Symbol;Acc:HGNC:545])

HSP 1 Score: 294.664 bits (753), Expect = 6.519e-95
Identity = 155/349 (44.41%), Postives = 222/349 (63.61%), Query Frame = 1
Query:   88 SEFIIIKPLSSR*MDQIGVKGERYKGTIKPFPNFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDLDYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFV 1134
            S + +  P+S     +     +  +GTI+P  NF+   D E+LRKAMKG GTDE+AI++ +  R   QR +IK  +KT +GKDLI+ LKSE+SGN ++ ++       YYDA+SL +AM+GAGT+E VL EIL +R+N +I  I   Y+  F  DLE+DI  +TSG F+R+LVS  Q N+ E  N+ I            N   A+++A  LY AGE ++GTDE+ F  I   R+  QLRAT + Y ++A +D+  S+  E SG ++S LK I   A+N+P +FA +LY +MKGAGT+D+TLVR+++TRSEIDL+ IK+ F + +  TL   +  DTSGDYR  L+  V
Sbjct:  152 SSYPVFSPVSLDYSSEPATVTQVTQGTIRPAANFDAIRDAEILRKAMKGFGTDEQAIVDVVANRSNDQRQKIKAAFKTSYGKDLIKDLKSELSGNMEELILALFMPPTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIREIVRCYQSEFGRDLEKDIRSDTSGHFERLLVSMCQGNRDE--NQSI------------NHQMAQEDAQRLYQAGEGRLGTDESCFNMILATRSFPQLRATMEAYSRMANRDLLSSVSREFSGYVESGLKTILQCALNRPAFFAERLYYAMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFAQMYQKTLGTMIAGDTSGDYRRLLLAIV 486          

HSP 2 Score: 76.6406 bits (187), Expect = 1.589e-14
Identity = 47/167 (28.14%), Postives = 83/167 (49.70%), Query Frame = 1
Query:  649 IREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN*D 1149
            + +V +  I    N +  R    E+     K  GTDE   + +   R+  Q +     ++   GKD+   + SE+SG+++ ++ A+        +Y A  L K+M+GAGT +  L+ +L TR+  ++  I + +Q EF   LE  ++ DTSG +   L+   +GN D
Sbjct:  171 VTQVTQGTIRPAANFDAIRD--AEILRKAMKGFGTDEQAIVDVVANRSNDQRQKIKAAFKTSYGKDLIKDLKSELSGNMEELILALFMPPT---YYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIREIVRCYQSEFGRDLEKDIRSDTSGHFERLLVSMCQGNRD 332          
BLAST of Annexin vs. Ensembl Human
Match: ANXA5 (annexin A5 [Source:HGNC Symbol;Acc:HGNC:543])

HSP 1 Score: 282.722 bits (722), Expect = 1.585e-92
Identity = 145/322 (45.03%), Postives = 208/322 (64.60%), Query Frame = 1
Query:  160 KGTIKPFPNFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDLDYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLM 1125
            +GT+  FP F+   D E LRKAMKG+GTDE++I+  L  R  AQR EI   +KT+FG+DL++ LKSE++G F+K ++  +     YDA+ L  A+KGAGT E VLTEI+ SR+  ++  IK +Y++ +   LE D++ +TSG+++R+LV  LQAN              R   A ++  Q  Q+A  L+ AGE K GTDE  FI IF  R+   LR  FD+Y  I+G  I ++ID E SG+L+ +L A+     + P Y A  LY +MKGAGT+D TL+RV+++RSEIDL NI+KEF++ F  +L + +K DTSGDY+  L+
Sbjct:    6 RGTVTDFPGFDERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEISAAFKTLFGRDLLDDLKSELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTNEKVLTEIIASRTPEELRAIKQVYEEEYGSSLEDDVVGDTSGYYQRMLVVLLQAN--------------RDPDAGIDEAQVEQDAQALFQAGELKWGTDEEKFITIFGTRSVSHLRKVFDKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVMVSRSEIDLFNIRKEFRKNFATSLYSMIKGDTSGDYKKALL 313          

HSP 2 Score: 72.7886 bits (177), Expect = 1.444e-13
Identity = 42/139 (30.22%), Postives = 78/139 (56.12%), Query Frame = 1
Query:  739 KKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKP--FYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN*D 1149
            K +GTDE   + +   R+  Q +     ++ + G+D+ D + SE++G  + ++ A+      KP   Y A +L  ++KGAGTN+  L  ++ +R+  +L  IK+ ++ E+  +LE+ V  DTSG Y+  L+  ++ N D
Sbjct:   29 KGLGTDEESILTLLTSRSNAQRQEISAAFKTLFGRDLLDDLKSELTGKFEKLIVALM-----KPSRLYDAYELKHALKGAGTNEKVLTEIIASRTPEELRAIKQVYEEEYGSSLEDDVVGDTSGYYQRMLVVLLQANRD 162          

HSP 3 Score: 66.2402 bits (160), Expect = 2.222e-11
Identity = 65/254 (25.59%), Postives = 109/254 (42.91%), Query Frame = 1
Query:  418 DAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGE-----KKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYF---------ATKLYKSMK-GAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFV 1134
            DA +L +AMKG GT E  +  +LTSRSN Q + I   +K  F  DL  D+  E +G F++++V+ ++ ++                               LY+A E     K  GT+E +  +I   R   +LRA    YE+  G  + D +  + SG  Q +L  +  QA   P            A  L+++ +   GT++   + +  TRS   L  +  ++       +E  +  +TSG+    L+  V
Sbjct:   20 DAETLRKAMKGLGTDEESILTLLTSRSNAQRQEISAAFKTLFGRDLLDDLKSELTGKFEKLIVALMKPSR-------------------------------LYDAYELKHALKGAGTNEKVLTEIIASRTPEELRAIKQVYEEEYGSSLEDDVVGDTSGYYQRML-VVLLQANRDPDAGIDEAQVEQDAQALFQAGELKWGTDEEKFITIFGTRSVSHLRKVFDKYMTISGFQIEETIDRETSGNLEQLLLAVV 241          
BLAST of Annexin vs. Ensembl Human
Match: ANXA11 (annexin A11 [Source:HGNC Symbol;Acc:HGNC:535])

HSP 1 Score: 286.189 bits (731), Expect = 7.832e-92
Identity = 148/328 (45.12%), Postives = 212/328 (64.63%), Query Frame = 1
Query:  160 KGTIKPFPNFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDLDYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN 1143
            +GTI   P F+   D EVLRKAMKG GTDE+AII+CLG R   QR +I  ++KT +GKDLI+ LKSE+SGNF+K ++  +     +D + + EA+KG GT E  L EIL SRSN  I  +   YK  F   LE+ I  +TSG F+R+L+S  Q N+ E TN              V+++ A+++A ELY AGE ++GTDE+ F  + C R++  L A F+EY+++ G+DI  SI  EMSGDL+  + A+     N P +FA +L K+M+GAGT D TL+R++++RSE DLL+I+ E++R +  +L + +  DTSGDYR  L++   GN
Sbjct:  158 RGTITDAPGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFEKTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILASRSNEHIRELNRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDESTN--------------VDMSLAQRDAQELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEGMLAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKSLYHDISGDTSGDYRKILLKICGGN 471          

HSP 2 Score: 67.3958 bits (163), Expect = 1.455e-11
Identity = 39/138 (28.26%), Postives = 72/138 (52.17%), Query Frame = 1
Query:  739 KKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFAT-KLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN*D 1149
            K  GTDE   I     R+  Q +     ++   GKD+   + SE+SG+ +  + A+    +  P  F   ++ +++KG GT++  L+ +L +RS   +  + + ++ EF  TLE  ++ DTSG ++  L+   +GN D
Sbjct:  181 KGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFEKTILAL----MKTPVLFDIYEIKEAIKGVGTDEACLIEILASRSNEHIRELNRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRD 314          
BLAST of Annexin vs. Ensembl Human
Match: ANXA11 (annexin A11 [Source:HGNC Symbol;Acc:HGNC:535])

HSP 1 Score: 285.804 bits (730), Expect = 2.521e-91
Identity = 148/328 (45.12%), Postives = 212/328 (64.63%), Query Frame = 1
Query:  160 KGTIKPFPNFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDLDYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN 1143
            +GTI   P F+   D EVLRKAMKG GTDE+AII+CLG R   QR +I  ++KT +GKDLI+ LKSE+SGNF+K ++  +     +D + + EA+KG GT E  L EIL SRSN  I  +   YK  F   LE+ I  +TSG F+R+L+S  Q N+ E TN              V+++ A+++A ELY AGE ++GTDE+ F  + C R++  L A F+EY+++ G+DI  SI  EMSGDL+  + A+     N P +FA +L K+M+GAGT D TL+R++++RSE DLL+I+ E++R +  +L + +  DTSGDYR  L++   GN
Sbjct:  191 RGTITDAPGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFEKTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILASRSNEHIRELNRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDESTN--------------VDMSLAQRDAQELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEGMLAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKSLYHDISGDTSGDYRKILLKICGGN 504          

HSP 2 Score: 67.3958 bits (163), Expect = 1.595e-11
Identity = 39/138 (28.26%), Postives = 72/138 (52.17%), Query Frame = 1
Query:  739 KKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFAT-KLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN*D 1149
            K  GTDE   I     R+  Q +     ++   GKD+   + SE+SG+ +  + A+    +  P  F   ++ +++KG GT++  L+ +L +RS   +  + + ++ EF  TLE  ++ DTSG ++  L+   +GN D
Sbjct:  214 KGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFEKTILAL----MKTPVLFDIYEIKEAIKGVGTDEACLIEILASRSNEHIRELNRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRD 347          
BLAST of Annexin vs. Ensembl Celegans
Match: nex-2 (Annexin [Source:UniProtKB/TrEMBL;Acc:Q7JMT5])

HSP 1 Score: 256.144 bits (653), Expect = 8.263e-81
Identity = 143/329 (43.47%), Postives = 198/329 (60.18%), Query Frame = 1
Query:  163 GTIKPFP--NFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDLDYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN 1143
            GT   FP   FN   D EVLRKAMKG+G +   +I  L +R   QR EI K +K M+GKDLI+ LK E+ G+F+  ++  +     YDA  LH AM+G GT+E+VL EI+TSR+N QI+ ++  YK  F  DLE+D+I ETSG FKR+LVS     + E +       Q  G+       +A Q+A  L  AGEK++GTDE+ F  I   +N  QLR  F+EY+K +   I  +I+ E SGD++  L A+     N+P YFA  L+ SMKG GT D  L+R+ +TR+E D+ +I+  FQ  +  +LEN +K D SG Y+  L+  V GN
Sbjct:  139 GTPSVFPVQGFNSNADAEVLRKAMKGLGCNNSKVISILCQRTNWQRQEISKAFKVMYGKDLIKELKGELHGDFEDLILALMDAPAIYDAKQLHRAMEGLGTKESVLIEIMTSRTNAQIQQVRDAYKMLFKKDLERDLIGETSGHFKRLLVSLCAGGRDESS-------QTDGL-------RANQDARRLLQAGEKRLGTDESTFNAILASQNFSQLRLVFEEYQKASNHSIEKAIEFEFSGDIRDGLLAVIAVIRNRPAYFAKLLHDSMKGLGTRDNDLIRLCVTRAEYDMGDIRNMFQSLYRTSLENMIKGDCSGAYKEGLIALVNGN 453          

HSP 2 Score: 60.077 bits (144), Expect = 1.174e-9
Identity = 38/142 (26.76%), Postives = 74/142 (52.11%), Query Frame = 1
Query:  211 VLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKK---AVIESLYDLDYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANK 627
            +L+   K +GTDE      L  +  +Q   + + Y+      + +A++ E SG+ +    AVI  + +   Y A  LH++MKG GTR+N L  +  +R+ + + +I+ +++  +   LE  I  + SG +K  L++ +  N+
Sbjct:  313 LLQAGEKRLGTDESTFNAILASQNFSQLRLVFEEYQKASNHSIEKAIEFEFSGDIRDGLLAVIAVIRNRPAYFAKLLHDSMKGLGTRDNDLIRLCVTRAEYDMGDIRNMFQSLYRTSLENMIKGDCSGAYKEGLIALVNGNR 454          
BLAST of Annexin vs. Ensembl Celegans
Match: nex-2 (Annexin [Source:UniProtKB/TrEMBL;Acc:Q7JMT5])

HSP 1 Score: 256.144 bits (653), Expect = 8.263e-81
Identity = 143/329 (43.47%), Postives = 198/329 (60.18%), Query Frame = 1
Query:  163 GTIKPFP--NFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDLDYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN 1143
            GT   FP   FN   D EVLRKAMKG+G +   +I  L +R   QR EI K +K M+GKDLI+ LK E+ G+F+  ++  +     YDA  LH AM+G GT+E+VL EI+TSR+N QI+ ++  YK  F  DLE+D+I ETSG FKR+LVS     + E +       Q  G+       +A Q+A  L  AGEK++GTDE+ F  I   +N  QLR  F+EY+K +   I  +I+ E SGD++  L A+     N+P YFA  L+ SMKG GT D  L+R+ +TR+E D+ +I+  FQ  +  +LEN +K D SG Y+  L+  V GN
Sbjct:  139 GTPSVFPVQGFNSNADAEVLRKAMKGLGCNNSKVISILCQRTNWQRQEISKAFKVMYGKDLIKELKGELHGDFEDLILALMDAPAIYDAKQLHRAMEGLGTKESVLIEIMTSRTNAQIQQVRDAYKMLFKKDLERDLIGETSGHFKRLLVSLCAGGRDESS-------QTDGL-------RANQDARRLLQAGEKRLGTDESTFNAILASQNFSQLRLVFEEYQKASNHSIEKAIEFEFSGDIRDGLLAVIAVIRNRPAYFAKLLHDSMKGLGTRDNDLIRLCVTRAEYDMGDIRNMFQSLYRTSLENMIKGDCSGAYKEGLIALVNGN 453          

HSP 2 Score: 60.077 bits (144), Expect = 1.174e-9
Identity = 38/142 (26.76%), Postives = 74/142 (52.11%), Query Frame = 1
Query:  211 VLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKK---AVIESLYDLDYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANK 627
            +L+   K +GTDE      L  +  +Q   + + Y+      + +A++ E SG+ +    AVI  + +   Y A  LH++MKG GTR+N L  +  +R+ + + +I+ +++  +   LE  I  + SG +K  L++ +  N+
Sbjct:  313 LLQAGEKRLGTDESTFNAILASQNFSQLRLVFEEYQKASNHSIEKAIEFEFSGDIRDGLLAVIAVIRNRPAYFAKLLHDSMKGLGTRDNDLIRLCVTRAEYDMGDIRNMFQSLYRTSLENMIKGDCSGAYKEGLIALVNGNR 454          
BLAST of Annexin vs. Ensembl Celegans
Match: nex-2 (Annexin [Source:UniProtKB/TrEMBL;Acc:Q7JMT5])

HSP 1 Score: 256.144 bits (653), Expect = 2.526e-80
Identity = 143/329 (43.47%), Postives = 198/329 (60.18%), Query Frame = 1
Query:  163 GTIKPFP--NFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDLDYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN 1143
            GT   FP   FN   D EVLRKAMKG+G +   +I  L +R   QR EI K +K M+GKDLI+ LK E+ G+F+  ++  +     YDA  LH AM+G GT+E+VL EI+TSR+N QI+ ++  YK  F  DLE+D+I ETSG FKR+LVS     + E +       Q  G+       +A Q+A  L  AGEK++GTDE+ F  I   +N  QLR  F+EY+K +   I  +I+ E SGD++  L A+     N+P YFA  L+ SMKG GT D  L+R+ +TR+E D+ +I+  FQ  +  +LEN +K D SG Y+  L+  V GN
Sbjct:  181 GTPSVFPVQGFNSNADAEVLRKAMKGLGCNNSKVISILCQRTNWQRQEISKAFKVMYGKDLIKELKGELHGDFEDLILALMDAPAIYDAKQLHRAMEGLGTKESVLIEIMTSRTNAQIQQVRDAYKMLFKKDLERDLIGETSGHFKRLLVSLCAGGRDESS-------QTDGL-------RANQDARRLLQAGEKRLGTDESTFNAILASQNFSQLRLVFEEYQKASNHSIEKAIEFEFSGDIRDGLLAVIAVIRNRPAYFAKLLHDSMKGLGTRDNDLIRLCVTRAEYDMGDIRNMFQSLYRTSLENMIKGDCSGAYKEGLIALVNGN 495          

HSP 2 Score: 60.077 bits (144), Expect = 1.332e-9
Identity = 38/142 (26.76%), Postives = 74/142 (52.11%), Query Frame = 1
Query:  211 VLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKK---AVIESLYDLDYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANK 627
            +L+   K +GTDE      L  +  +Q   + + Y+      + +A++ E SG+ +    AVI  + +   Y A  LH++MKG GTR+N L  +  +R+ + + +I+ +++  +   LE  I  + SG +K  L++ +  N+
Sbjct:  355 LLQAGEKRLGTDESTFNAILASQNFSQLRLVFEEYQKASNHSIEKAIEFEFSGDIRDGLLAVIAVIRNRPAYFAKLLHDSMKGLGTRDNDLIRLCVTRAEYDMGDIRNMFQSLYRTSLENMIKGDCSGAYKEGLIALVNGNR 496          
BLAST of Annexin vs. Ensembl Celegans
Match: nex-1 (Annexin [Source:UniProtKB/TrEMBL;Acc:G5EEA8])

HSP 1 Score: 196.823 bits (499), Expect = 1.708e-59
Identity = 122/328 (37.20%), Postives = 181/328 (55.18%), Query Frame = 1
Query:  163 GTIKPFPNFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDLDYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGT-DEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN 1143
             TI     FN     E + +A++    ++ A++  +     AQR ++++ YK  +GKD+I+AL  + SG+ +KA+   +     YD   L  AMKG GT E VL EIL SR+  Q+  I++ Y+K +   LE DI  +TSG F+ +LVS +  +K                S   N  QA+ +A  L+  G+ K+   D   F+ I   +N+YQLR  F  ++++AG  I  SI+ E SGDLQ     I   A +K  +FA +L+ SMKG GT D  L+RV++TRSE+DL  IK EFQ  ++ +L + VK DTSG YR  L+  + GN
Sbjct:    6 ATIVDAREFNAPMFAEKIDRALRA--GEKDAVVNVITSISNAQRQQLREPYKLKYGKDIIQALDKKFSGDLEKAIFALMETPLDYDVKQLKAAMKGLGTDEAVLIEILCSRTVDQLRAIRVTYEKEYGKALEADIAGDTSGEFRDLLVSLVTGSKDG--------------SHDTNDAQAKDDAVRLFADGKAKLAKKDGTHFLHILATQNQYQLRKVFAYFQELAGGSIEKSIEKEFSGDLQKSYLTIVRAASDKQKFFAQQLHASMKGLGTRDNDLIRVIVTRSEVDLELIKAEFQELYSKSLADTVKGDTSGAYRDALLSIINGN 317          

HSP 2 Score: 63.929 bits (154), Expect = 3.877e-11
Identity = 46/139 (33.09%), Postives = 76/139 (54.68%), Query Frame = 1
Query:  742 KIGTDEAMFIKIFCMRN--KYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPF-YFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN*D 1149
            + G  +A+   I  + N  + QLR   + Y+   GKDI  ++D + SGDL+   KAI F  +  P  Y   +L  +MKG GT++  L+ +L +R+   L  I+  +++E+   LE  +  DTSG++R  L+  V G+ D
Sbjct:   28 RAGEKDAVVNVITSISNAQRQQLR---EPYKLKYGKDIIQALDKKFSGDLE---KAI-FALMETPLDYDVKQLKAAMKGLGTDEAVLIEILCSRTVDQLRAIRVTYEKEYGKALEADIAGDTSGEFRDLLVSLVTGSKD 159          
BLAST of Annexin vs. Ensembl Celegans
Match: nex-1 (Annexin [Source:UniProtKB/TrEMBL;Acc:G5EEA8])

HSP 1 Score: 196.823 bits (499), Expect = 1.708e-59
Identity = 122/328 (37.20%), Postives = 181/328 (55.18%), Query Frame = 1
Query:  163 GTIKPFPNFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDLDYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGT-DEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN 1143
             TI     FN     E + +A++    ++ A++  +     AQR ++++ YK  +GKD+I+AL  + SG+ +KA+   +     YD   L  AMKG GT E VL EIL SR+  Q+  I++ Y+K +   LE DI  +TSG F+ +LVS +  +K                S   N  QA+ +A  L+  G+ K+   D   F+ I   +N+YQLR  F  ++++AG  I  SI+ E SGDLQ     I   A +K  +FA +L+ SMKG GT D  L+RV++TRSE+DL  IK EFQ  ++ +L + VK DTSG YR  L+  + GN
Sbjct:    6 ATIVDAREFNAPMFAEKIDRALRA--GEKDAVVNVITSISNAQRQQLREPYKLKYGKDIIQALDKKFSGDLEKAIFALMETPLDYDVKQLKAAMKGLGTDEAVLIEILCSRTVDQLRAIRVTYEKEYGKALEADIAGDTSGEFRDLLVSLVTGSKDG--------------SHDTNDAQAKDDAVRLFADGKAKLAKKDGTHFLHILATQNQYQLRKVFAYFQELAGGSIEKSIEKEFSGDLQKSYLTIVRAASDKQKFFAQQLHASMKGLGTRDNDLIRVIVTRSEVDLELIKAEFQELYSKSLADTVKGDTSGAYRDALLSIINGN 317          

HSP 2 Score: 63.929 bits (154), Expect = 3.877e-11
Identity = 46/139 (33.09%), Postives = 76/139 (54.68%), Query Frame = 1
Query:  742 KIGTDEAMFIKIFCMRN--KYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPF-YFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN*D 1149
            + G  +A+   I  + N  + QLR   + Y+   GKDI  ++D + SGDL+   KAI F  +  P  Y   +L  +MKG GT++  L+ +L +R+   L  I+  +++E+   LE  +  DTSG++R  L+  V G+ D
Sbjct:   28 RAGEKDAVVNVITSISNAQRQQLR---EPYKLKYGKDIIQALDKKFSGDLE---KAI-FALMETPLDYDVKQLKAAMKGLGTDEAVLIEILCSRTVDQLRAIRVTYEKEYGKALEADIAGDTSGEFRDLLVSLVTGSKD 159          
BLAST of Annexin vs. Ensembl Fly
Match: AnxB11 (gene:FBgn0030749 transcript:FBtr0334038)

HSP 1 Score: 256.144 bits (653), Expect = 2.147e-82
Identity = 147/324 (45.37%), Postives = 197/324 (60.80%), Query Frame = 1
Query:  166 TIKPFPNFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDL-DYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFV 1134
            T+ P  NF+   D   LRKAMKG GTDE A+I  + RR   QR EI++ +KT FGKDLIE +KSE SGNF+K ++  L  + DYY A  L++AM G GT E VL EIL + SN +I  IK  Y + +   LE ++  ETSG FKR+L S   A + E              S  V+   A+ +A EL  AGE ++GTDE+MF  I C RN  QL+  F EYE + G  +  +I  E SGD+   L AI     NK  YFA++L+K+M G GTNDT L+RV++TRSEID+ +IK  F+R +  +L++++K DTSG Y+  L   V
Sbjct:    8 TVVPAANFDAVKDAHDLRKAMKGFGTDEDALINIICRRSNEQRQEIQRQFKTHFGKDLIEDIKSETSGNFEKLLVGLLRPIVDYYCA-ELNDAMAGLGTDEEVLIEILCTLSNMEINTIKNQYLRLYGAHLESELKSETSGNFKRLLTSLCTAARDE--------------SGRVDPVAAKNDARELLKAGELRVGTDESMFNMILCQRNYQQLKLIFQEYEGMTGHSLEKAIKKEFSGDVMEGLIAIYRCVTNKAEYFASRLHKAMAGIGTNDTQLIRVIITRSEIDMTDIKVAFERLYGKSLKSWIKGDTSGHYKHALYALV 316          
BLAST of Annexin vs. Ensembl Fly
Match: AnxB11 (gene:FBgn0030749 transcript:FBtr0074302)

HSP 1 Score: 256.144 bits (653), Expect = 2.147e-82
Identity = 147/324 (45.37%), Postives = 197/324 (60.80%), Query Frame = 1
Query:  166 TIKPFPNFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDL-DYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFV 1134
            T+ P  NF+   D   LRKAMKG GTDE A+I  + RR   QR EI++ +KT FGKDLIE +KSE SGNF+K ++  L  + DYY A  L++AM G GT E VL EIL + SN +I  IK  Y + +   LE ++  ETSG FKR+L S   A + E              S  V+   A+ +A EL  AGE ++GTDE+MF  I C RN  QL+  F EYE + G  +  +I  E SGD+   L AI     NK  YFA++L+K+M G GTNDT L+RV++TRSEID+ +IK  F+R +  +L++++K DTSG Y+  L   V
Sbjct:    8 TVVPAANFDAVKDAHDLRKAMKGFGTDEDALINIICRRSNEQRQEIQRQFKTHFGKDLIEDIKSETSGNFEKLLVGLLRPIVDYYCA-ELNDAMAGLGTDEEVLIEILCTLSNMEINTIKNQYLRLYGAHLESELKSETSGNFKRLLTSLCTAARDE--------------SGRVDPVAAKNDARELLKAGELRVGTDESMFNMILCQRNYQQLKLIFQEYEGMTGHSLEKAIKKEFSGDVMEGLIAIYRCVTNKAEYFASRLHKAMAGIGTNDTQLIRVIITRSEIDMTDIKVAFERLYGKSLKSWIKGDTSGHYKHALYALV 316          
BLAST of Annexin vs. Ensembl Fly
Match: AnxB11 (gene:FBgn0030749 transcript:FBtr0334041)

HSP 1 Score: 256.144 bits (653), Expect = 2.147e-82
Identity = 147/324 (45.37%), Postives = 197/324 (60.80%), Query Frame = 1
Query:  166 TIKPFPNFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDL-DYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFV 1134
            T+ P  NF+   D   LRKAMKG GTDE A+I  + RR   QR EI++ +KT FGKDLIE +KSE SGNF+K ++  L  + DYY A  L++AM G GT E VL EIL + SN +I  IK  Y + +   LE ++  ETSG FKR+L S   A + E              S  V+   A+ +A EL  AGE ++GTDE+MF  I C RN  QL+  F EYE + G  +  +I  E SGD+   L AI     NK  YFA++L+K+M G GTNDT L+RV++TRSEID+ +IK  F+R +  +L++++K DTSG Y+  L   V
Sbjct:    8 TVVPAANFDAVKDAHDLRKAMKGFGTDEDALINIICRRSNEQRQEIQRQFKTHFGKDLIEDIKSETSGNFEKLLVGLLRPIVDYYCA-ELNDAMAGLGTDEEVLIEILCTLSNMEINTIKNQYLRLYGAHLESELKSETSGNFKRLLTSLCTAARDE--------------SGRVDPVAAKNDARELLKAGELRVGTDESMFNMILCQRNYQQLKLIFQEYEGMTGHSLEKAIKKEFSGDVMEGLIAIYRCVTNKAEYFASRLHKAMAGIGTNDTQLIRVIITRSEIDMTDIKVAFERLYGKSLKSWIKGDTSGHYKHALYALV 316          
BLAST of Annexin vs. Ensembl Fly
Match: AnxB11 (gene:FBgn0030749 transcript:FBtr0334040)

HSP 1 Score: 255.758 bits (652), Expect = 6.065e-80
Identity = 147/324 (45.37%), Postives = 197/324 (60.80%), Query Frame = 1
Query:  166 TIKPFPNFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDL-DYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFV 1134
            T+ P  NF+   D   LRKAMKG GTDE A+I  + RR   QR EI++ +KT FGKDLIE +KSE SGNF+K ++  L  + DYY A  L++AM G GT E VL EIL + SN +I  IK  Y + +   LE ++  ETSG FKR+L S   A + E              S  V+   A+ +A EL  AGE ++GTDE+MF  I C RN  QL+  F EYE + G  +  +I  E SGD+   L AI     NK  YFA++L+K+M G GTNDT L+RV++TRSEID+ +IK  F+R +  +L++++K DTSG Y+  L   V
Sbjct:  197 TVVPAANFDAVKDAHDLRKAMKGFGTDEDALINIICRRSNEQRQEIQRQFKTHFGKDLIEDIKSETSGNFEKLLVGLLRPIVDYYCA-ELNDAMAGLGTDEEVLIEILCTLSNMEINTIKNQYLRLYGAHLESELKSETSGNFKRLLTSLCTAARDE--------------SGRVDPVAAKNDARELLKAGELRVGTDESMFNMILCQRNYQQLKLIFQEYEGMTGHSLEKAIKKEFSGDVMEGLIAIYRCVTNKAEYFASRLHKAMAGIGTNDTQLIRVIITRSEIDMTDIKVAFERLYGKSLKSWIKGDTSGHYKHALYALV 505          
BLAST of Annexin vs. Ensembl Fly
Match: AnxB11 (gene:FBgn0030749 transcript:FBtr0074303)

HSP 1 Score: 255.758 bits (652), Expect = 6.065e-80
Identity = 147/324 (45.37%), Postives = 197/324 (60.80%), Query Frame = 1
Query:  166 TIKPFPNFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDL-DYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFV 1134
            T+ P  NF+   D   LRKAMKG GTDE A+I  + RR   QR EI++ +KT FGKDLIE +KSE SGNF+K ++  L  + DYY A  L++AM G GT E VL EIL + SN +I  IK  Y + +   LE ++  ETSG FKR+L S   A + E              S  V+   A+ +A EL  AGE ++GTDE+MF  I C RN  QL+  F EYE + G  +  +I  E SGD+   L AI     NK  YFA++L+K+M G GTNDT L+RV++TRSEID+ +IK  F+R +  +L++++K DTSG Y+  L   V
Sbjct:  197 TVVPAANFDAVKDAHDLRKAMKGFGTDEDALINIICRRSNEQRQEIQRQFKTHFGKDLIEDIKSETSGNFEKLLVGLLRPIVDYYCA-ELNDAMAGLGTDEEVLIEILCTLSNMEINTIKNQYLRLYGAHLESELKSETSGNFKRLLTSLCTAARDE--------------SGRVDPVAAKNDARELLKAGELRVGTDESMFNMILCQRNYQQLKLIFQEYEGMTGHSLEKAIKKEFSGDVMEGLIAIYRCVTNKAEYFASRLHKAMAGIGTNDTQLIRVIITRSEIDMTDIKVAFERLYGKSLKSWIKGDTSGHYKHALYALV 505          
BLAST of Annexin vs. Ensembl Zebrafish
Match: anxa11a (annexin A11a [Source:ZFIN;Acc:ZDB-GENE-030707-4])

HSP 1 Score: 299.286 bits (765), Expect = 6.265e-97
Identity = 155/329 (47.11%), Postives = 214/329 (65.05%), Query Frame = 1
Query:  157 YKGTIKPFPNFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDLDYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN 1143
            ++G+I+ FP  +   D EVLRKAMKG GTDE+AII  LG R   QR+ +  +YKT +GKDLI+ LKSE+SGNF+K V+  L     YDA+ L EA+KGAGT E  L EIL SRSN +I  I  ++K      LE  I  +TSG F+R+LVS  Q N+ E  N              V+I+ A+ +A  LY AGE K+GTDE+ F  I C R+K  LRA F+EY+ + G+DI  SI+ EMSGDL+S + A+     N P YFA +L+K+MKGAGT D TL+R+++TRSE+D+L+I++E+ + +  +L   +  DTSGDY+  L++   G+
Sbjct:  168 FRGSIQDFPGADPLRDAEVLRKAMKGFGTDEQAIINLLGSRSNKQRVPLLVSYKTAYGKDLIKDLKSELSGNFEKLVLAMLKTPSQYDAYELKEAIKGAGTDEACLIEILASRSNAEIREINQVFKAENKKSLEDAISGDTSGHFRRLLVSLAQGNRDESEN--------------VDISIAKTDAQALYQAGENKLGTDESKFNAILCARSKAHLRAVFNEYQHMCGRDIEKSIEREMSGDLESGMLAVVKCIKNTPAYFAERLHKAMKGAGTKDRTLIRIMVTRSEVDMLDIRQEYAKNYGKSLYTAISGDTSGDYKKLLLKLCGGS 482          

HSP 2 Score: 74.3294 bits (181), Expect = 5.517e-14
Identity = 43/137 (31.39%), Postives = 73/137 (53.28%), Query Frame = 1
Query:  739 KKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN*D 1149
            K  GTDE   I +   R+  Q       Y+   GKD+   + SE+SG+ + ++ A+         Y A +L +++KGAGT++  L+ +L +RS  ++  I + F+ E   +LE+ +  DTSG +R  L+   +GN D
Sbjct:  192 KGFGTDEQAIINLLGSRSNKQRVPLLVSYKTAYGKDLIKDLKSELSGNFEKLVLAMLKTPSQ---YDAYELKEAIKGAGTDEACLIEILASRSNAEIREINQVFKAENKKSLEDAISGDTSGHFRRLLVSLAQGNRD 325          
BLAST of Annexin vs. Ensembl Zebrafish
Match: anxa11a (annexin A11a [Source:ZFIN;Acc:ZDB-GENE-030707-4])

HSP 1 Score: 298.901 bits (764), Expect = 2.781e-96
Identity = 155/329 (47.11%), Postives = 214/329 (65.05%), Query Frame = 1
Query:  157 YKGTIKPFPNFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDLDYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN 1143
            ++G+I+ FP  +   D EVLRKAMKG GTDE+AII  LG R   QR+ +  +YKT +GKDLI+ LKSE+SGNF+K V+  L     YDA+ L EA+KGAGT E  L EIL SRSN +I  I  ++K      LE  I  +TSG F+R+LVS  Q N+ E  N              V+I+ A+ +A  LY AGE K+GTDE+ F  I C R+K  LRA F+EY+ + G+DI  SI+ EMSGDL+S + A+     N P YFA +L+K+MKGAGT D TL+R+++TRSE+D+L+I++E+ + +  +L   +  DTSGDY+  L++   G+
Sbjct:  211 FRGSIQDFPGADPLRDAEVLRKAMKGFGTDEQAIINLLGSRSNKQRVPLLVSYKTAYGKDLIKDLKSELSGNFEKLVLAMLKTPSQYDAYELKEAIKGAGTDEACLIEILASRSNAEIREINQVFKAENKKSLEDAISGDTSGHFRRLLVSLAQGNRDESEN--------------VDISIAKTDAQALYQAGENKLGTDESKFNAILCARSKAHLRAVFNEYQHMCGRDIEKSIEREMSGDLESGMLAVVKCIKNTPAYFAERLHKAMKGAGTKDRTLIRIMVTRSEVDMLDIRQEYAKNYGKSLYTAISGDTSGDYKKLLLKLCGGS 525          

HSP 2 Score: 73.9442 bits (180), Expect = 7.624e-14
Identity = 43/137 (31.39%), Postives = 73/137 (53.28%), Query Frame = 1
Query:  739 KKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN*D 1149
            K  GTDE   I +   R+  Q       Y+   GKD+   + SE+SG+ + ++ A+         Y A +L +++KGAGT++  L+ +L +RS  ++  I + F+ E   +LE+ +  DTSG +R  L+   +GN D
Sbjct:  235 KGFGTDEQAIINLLGSRSNKQRVPLLVSYKTAYGKDLIKDLKSELSGNFEKLVLAMLKTPSQ---YDAYELKEAIKGAGTDEACLIEILASRSNAEIREINQVFKAENKKSLEDAISGDTSGHFRRLLVSLAQGNRD 368          
BLAST of Annexin vs. Ensembl Zebrafish
Match: anxa11b (annexin A11b [Source:ZFIN;Acc:ZDB-GENE-030707-5])

HSP 1 Score: 293.893 bits (751), Expect = 8.357e-95
Identity = 153/329 (46.50%), Postives = 214/329 (65.05%), Query Frame = 1
Query:  157 YKGTIKPFPNFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDLDYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN 1143
            ++GTIK FP  +   D EVLRKAMKG GTDE AIIE LG R   QR+ +   YKT +GKDL+  LKSE++G+F++ V+  L     +DA    EA+ GAGT E  L EIL+SRSN +I+ I  +YK  +   LE  I  +TSG F+R+LVS  Q N+ E      RE         V+I+ A+Q+A +LY+AGE K+GTDE+ F  I C R+K  LR  F EY+++ G+DI  SI  EMSGDL+S + A+     N P YFA +L+K+M+GAGT D TL+R++++RSE+D+L+I++E+ R F  +L   +  DTSGDY+  L++   G+
Sbjct:  170 FRGTIKDFPGADPLRDVEVLRKAMKGFGTDENAIIELLGSRSNKQRVPLLAAYKTTYGKDLVRDLKSELTGHFEELVLAMLKSPAQFDASECKEAISGAGTDEACLIEILSSRSNAEIQEINRIYKAEYGKSLEDAISNDTSGHFRRLLVSLCQGNRDE------RET--------VDISLAKQDAQKLYSAGENKVGTDESQFNAILCARSKPHLRQVFQEYQQMCGRDIEKSICREMSGDLESGMVAVVKCIKNTPAYFAERLHKAMQGAGTKDRTLIRIMVSRSELDMLDIRQEYLRLFGKSLYTHISGDTSGDYKKLLLKLCGGS 484          

HSP 2 Score: 74.7146 bits (182), Expect = 4.389e-14
Identity = 41/140 (29.29%), Postives = 77/140 (55.00%), Query Frame = 1
Query:  739 KKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYF-ATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN*DSR 1155
            K  GTDE   I++   R+  Q       Y+   GKD+   + SE++G  + ++ A+    +  P  F A++  +++ GAGT++  L+ +L +RS  ++  I + ++ E+  +LE+ + +DTSG +R  L+   +GN D R
Sbjct:  194 KGFGTDENAIIELLGSRSNKQRVPLLAAYKTTYGKDLVRDLKSELTGHFEELVLAM----LKSPAQFDASECKEAISGAGTDEACLIEILSSRSNAEIQEINRIYKAEYGKSLEDAISNDTSGHFRRLLVSLCQGNRDER 329          
BLAST of Annexin vs. Ensembl Zebrafish
Match: anxa4 (annexin A4 [Source:ZFIN;Acc:ZDB-GENE-030707-1])

HSP 1 Score: 284.648 bits (727), Expect = 2.284e-93
Identity = 150/327 (45.87%), Postives = 203/327 (62.08%), Query Frame = 1
Query:  160 KGTIKPFPNFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDLDYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEG 1140
            +GT+     F  E D + +  AMKG GT+E  IIE L  R +AQR +IK+ +K   GK+L++ LKSE++GNF+K V+  +     YDA  L  A+KGAGT E  L +IL SRSN +I+ I   YKK  +  LE DI  +TSG F+RVLVS L A + E T               V+  QA Q+A ++Y AGE + GTDE  F+ + C+RN+  L   F EY+K +G+DI DSI  EMSG L+ V  AI     NKP +FA +LYKSMKG GT D+ L+R+++ R+EID+L+IK EF + +  TL +F+K DTSGDYR  L+    G
Sbjct:    7 RGTVTEASGFKPEDDAQKIYNAMKGAGTNEATIIEILAHRTIAQRQKIKEAFKLSVGKELMDCLKSELTGNFEKVVVGLMMPAAVYDAHELRNAIKGAGTEEACLIDILASRSNAEIKEIVAAYKKEHDKSLEDDICGDTSGMFQRVLVSLLTAGRDESTK--------------VDEAQAVQDAKDIYEAGEARWGTDEVKFLTVLCVRNRNHLLRVFQEYQKKSGRDIEDSIKREMSGSLEDVFLAIVKCIKNKPAFFAERLYKSMKGLGTTDSVLIRIMVARAEIDMLDIKAEFLKMYGKTLHSFIKGDTSGDYRKILLELCGG 319          

HSP 2 Score: 70.8626 bits (172), Expect = 3.607e-13
Identity = 43/147 (29.25%), Postives = 81/147 (55.10%), Query Frame = 1
Query:  709 EATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN*D 1149
            +A ++YNA  K  GT+EA  I+I   R   Q +   + ++   GK++ D + SE++G+ + V+  +   A     Y A +L  ++KGAGT +  L+ +L +RS  ++  I   +++E + +LE+ +  DTSG ++  L+  +    D
Sbjct:   21 DAQKIYNA-MKGAGTNEATIIEILAHRTIAQRQKIKEAFKLSVGKELMDCLKSELTGNFEKVVVGLMMPA---AVYDAHELRNAIKGAGTEEACLIDILASRSNAEIKEIVAAYKKEHDKSLEDDICGDTSGMFQRVLVSLLTAGRD 163          
BLAST of Annexin vs. Ensembl Zebrafish
Match: anxa4 (annexin A4 [Source:ZFIN;Acc:ZDB-GENE-030707-1])

HSP 1 Score: 284.648 bits (727), Expect = 2.284e-93
Identity = 150/327 (45.87%), Postives = 203/327 (62.08%), Query Frame = 1
Query:  160 KGTIKPFPNFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDLDYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEG 1140
            +GT+     F  E D + +  AMKG GT+E  IIE L  R +AQR +IK+ +K   GK+L++ LKSE++GNF+K V+  +     YDA  L  A+KGAGT E  L +IL SRSN +I+ I   YKK  +  LE DI  +TSG F+RVLVS L A + E T               V+  QA Q+A ++Y AGE + GTDE  F+ + C+RN+  L   F EY+K +G+DI DSI  EMSG L+ V  AI     NKP +FA +LYKSMKG GT D+ L+R+++ R+EID+L+IK EF + +  TL +F+K DTSGDYR  L+    G
Sbjct:    7 RGTVTEASGFKPEDDAQKIYNAMKGAGTNEATIIEILAHRTIAQRQKIKEAFKLSVGKELMDCLKSELTGNFEKVVVGLMMPAAVYDAHELRNAIKGAGTEEACLIDILASRSNAEIKEIVAAYKKEHDKSLEDDICGDTSGMFQRVLVSLLTAGRDESTK--------------VDEAQAVQDAKDIYEAGEARWGTDEVKFLTVLCVRNRNHLLRVFQEYQKKSGRDIEDSIKREMSGSLEDVFLAIVKCIKNKPAFFAERLYKSMKGLGTTDSVLIRIMVARAEIDMLDIKAEFLKMYGKTLHSFIKGDTSGDYRKILLELCGG 319          

HSP 2 Score: 70.8626 bits (172), Expect = 3.607e-13
Identity = 43/147 (29.25%), Postives = 81/147 (55.10%), Query Frame = 1
Query:  709 EATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN*D 1149
            +A ++YNA  K  GT+EA  I+I   R   Q +   + ++   GK++ D + SE++G+ + V+  +   A     Y A +L  ++KGAGT +  L+ +L +RS  ++  I   +++E + +LE+ +  DTSG ++  L+  +    D
Sbjct:   21 DAQKIYNA-MKGAGTNEATIIEILAHRTIAQRQKIKEAFKLSVGKELMDCLKSELTGNFEKVVVGLMMPA---AVYDAHELRNAIKGAGTEEACLIDILASRSNAEIKEIVAAYKKEHDKSLEDDICGDTSGMFQRVLVSLLTAGRD 163          
BLAST of Annexin vs. Ensembl Xenopus
Match: mllt10 (MLLT10, histone lysine methyltransferase DOT1L cofactor [Source:Xenbase;Acc:XB-GENE-6408100])

HSP 1 Score: 304.294 bits (778), Expect = 5.157e-101
Identity = 161/327 (49.24%), Postives = 208/327 (63.61%), Query Frame = 1
Query:  160 KGTIKPFPNFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDLDYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEG 1140
            KGTIKP+ NFN   D + LRKAMKG GTDE AII+ +  R L+QR EIK  YKT  GKDL + LKSE++GNF+K ++  +     YD   L +AMKGAGT E  L EIL SRS  +I+NI I Y+  +   LE DI  +TS  F+RVLVS     + + TN              VN   A+Q+A ELY AGEKK GTDE  F+ I C RN+  L   FDEY+KIA KD+  SI SEMSG  +  L A+     ++P YFA +LYKSMKG GT+D TL+RV+++R EID+L I+ EF++ +  +L +F+K D SGDYR  L++   G
Sbjct:    7 KGTIKPYANFNAADDVQKLRKAMKGAGTDEDAIIDVIANRTLSQRQEIKTAYKTTIGKDLEDDLKSELTGNFEKVIVGLITPSTLYDVEELKKAMKGAGTDEGCLIEILASRSAEEIKNINITYRIKYGKSLEDDICSDTSFMFQRVLVSLAAGGRDQSTN--------------VNEALAKQDANELYEAGEKKWGTDEVKFLTILCSRNRNHLLKVFDEYKKIAKKDLEASIKSEMSGHFEDALLAVVKCLRSRPGYFAERLYKSMKGLGTDDKTLIRVMVSRCEIDMLEIRSEFKKMYGKSLHSFIKGDCSGDYRKVLLKLCGG 319          

HSP 2 Score: 63.5438 bits (153), Expect = 1.238e-10
Identity = 40/137 (29.20%), Postives = 71/137 (51.82%), Query Frame = 1
Query:  739 KKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN*D 1149
            K  GTDE   I +   R   Q +     Y+   GKD+ D + SE++G+ + V+  +   +     Y   +L K+MKGAGT++  L+ +L +RS  ++ NI   ++ ++  +LE+ +  DTS  ++  L+    G  D
Sbjct:   30 KGAGTDEDAIIDVIANRTLSQRQEIKTAYKTTIGKDLEDDLKSELTGNFEKVIVGLITPST---LYDVEELKKAMKGAGTDEGCLIEILASRSAEEIKNINITYRIKYGKSLEDDICSDTSFMFQRVLVSLAAGGRD 163          
BLAST of Annexin vs. Ensembl Xenopus
Match: mllt10 (MLLT10, histone lysine methyltransferase DOT1L cofactor [Source:Xenbase;Acc:XB-GENE-6408100])

HSP 1 Score: 304.294 bits (778), Expect = 5.561e-101
Identity = 161/327 (49.24%), Postives = 208/327 (63.61%), Query Frame = 1
Query:  160 KGTIKPFPNFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDLDYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEG 1140
            KGTIKP+ NFN   D + LRKAMKG GTDE AII+ +  R L+QR EIK  YKT  GKDL + LKSE++GNF+K ++  +     YD   L +AMKGAGT E  L EIL SRS  +I+NI I Y+  +   LE DI  +TS  F+RVLVS     + + TN              VN   A+Q+A ELY AGEKK GTDE  F+ I C RN+  L   FDEY+KIA KD+  SI SEMSG  +  L A+     ++P YFA +LYKSMKG GT+D TL+RV+++R EID+L I+ EF++ +  +L +F+K D SGDYR  L++   G
Sbjct:    5 KGTIKPYANFNAADDVQKLRKAMKGAGTDEDAIIDVIANRTLSQRQEIKTAYKTTIGKDLEDDLKSELTGNFEKVIVGLITPSTLYDVEELKKAMKGAGTDEGCLIEILASRSAEEIKNINITYRIKYGKSLEDDICSDTSFMFQRVLVSLAAGGRDQSTN--------------VNEALAKQDANELYEAGEKKWGTDEVKFLTILCSRNRNHLLKVFDEYKKIAKKDLEASIKSEMSGHFEDALLAVVKCLRSRPGYFAERLYKSMKGLGTDDKTLIRVMVSRCEIDMLEIRSEFKKMYGKSLHSFIKGDCSGDYRKVLLKLCGG 317          

HSP 2 Score: 63.5438 bits (153), Expect = 1.233e-10
Identity = 40/137 (29.20%), Postives = 71/137 (51.82%), Query Frame = 1
Query:  739 KKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN*D 1149
            K  GTDE   I +   R   Q +     Y+   GKD+ D + SE++G+ + V+  +   +     Y   +L K+MKGAGT++  L+ +L +RS  ++ NI   ++ ++  +LE+ +  DTS  ++  L+    G  D
Sbjct:   28 KGAGTDEDAIIDVIANRTLSQRQEIKTAYKTTIGKDLEDDLKSELTGNFEKVIVGLITPST---LYDVEELKKAMKGAGTDEGCLIEILASRSAEEIKNINITYRIKYGKSLEDDICSDTSFMFQRVLVSLAAGGRD 161          
BLAST of Annexin vs. Ensembl Xenopus
Match: mllt10 (MLLT10, histone lysine methyltransferase DOT1L cofactor [Source:Xenbase;Acc:XB-GENE-6408100])

HSP 1 Score: 305.064 bits (780), Expect = 1.359e-100
Identity = 161/327 (49.24%), Postives = 208/327 (63.61%), Query Frame = 1
Query:  160 KGTIKPFPNFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDLDYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEG 1140
            KGTIKP+ NFN   D + LRKAMKG GTDE AII+ +  R L+QR EIK  YKT  GKDL + LKSE++GNF+K ++  +     YD   L +AMKGAGT E  L EIL SRS  +I+NI I Y+  +   LE DI  +TS  F+RVLVS     + + TN              VN   A+Q+A ELY AGEKK GTDE  F+ I C RN+  L   FDEY+KIA KD+  SI SEMSG  +  L A+     ++P YFA +LYKSMKG GT+D TL+RV+++R EID+L I+ EF++ +  +L +F+K D SGDYR  L++   G
Sbjct:   50 KGTIKPYANFNAADDVQKLRKAMKGAGTDEDAIIDVIANRTLSQRQEIKTAYKTTIGKDLEDDLKSELTGNFEKVIVGLITPSTLYDVEELKKAMKGAGTDEGCLIEILASRSAEEIKNINITYRIKYGKSLEDDICSDTSFMFQRVLVSLAAGGRDQSTN--------------VNEALAKQDANELYEAGEKKWGTDEVKFLTILCSRNRNHLLKVFDEYKKIAKKDLEASIKSEMSGHFEDALLAVVKCLRSRPGYFAERLYKSMKGLGTDDKTLIRVMVSRCEIDMLEIRSEFKKMYGKSLHSFIKGDCSGDYRKVLLKLCGG 362          

HSP 2 Score: 63.929 bits (154), Expect = 1.511e-10
Identity = 40/137 (29.20%), Postives = 71/137 (51.82%), Query Frame = 1
Query:  739 KKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN*D 1149
            K  GTDE   I +   R   Q +     Y+   GKD+ D + SE++G+ + V+  +   +     Y   +L K+MKGAGT++  L+ +L +RS  ++ NI   ++ ++  +LE+ +  DTS  ++  L+    G  D
Sbjct:   73 KGAGTDEDAIIDVIANRTLSQRQEIKTAYKTTIGKDLEDDLKSELTGNFEKVIVGLITPST---LYDVEELKKAMKGAGTDEGCLIEILASRSAEEIKNINITYRIKYGKSLEDDICSDTSFMFQRVLVSLAAGGRD 206          
BLAST of Annexin vs. Ensembl Xenopus
Match: mllt10 (MLLT10, histone lysine methyltransferase DOT1L cofactor [Source:Xenbase;Acc:XB-GENE-6408100])

HSP 1 Score: 303.908 bits (777), Expect = 1.447e-100
Identity = 161/327 (49.24%), Postives = 208/327 (63.61%), Query Frame = 1
Query:  160 KGTIKPFPNFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDLDYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEG 1140
            KGTIKP+ NFN   D + LRKAMKG GTDE AII+ +  R L+QR EIK  YKT  GKDL + LKSE++GNF+K ++  +     YD   L +AMKGAGT E  L EIL SRS  +I+NI I Y+  +   LE DI  +TS  F+RVLVS     + + TN              VN   A+Q+A ELY AGEKK GTDE  F+ I C RN+  L   FDEY+KIA KD+  SI SEMSG  +  L A+     ++P YFA +LYKSMKG GT+D TL+RV+++R EID+L I+ EF++ +  +L +F+K D SGDYR  L++   G
Sbjct:   27 KGTIKPYANFNAADDVQKLRKAMKGAGTDEDAIIDVIANRTLSQRQEIKTAYKTTIGKDLEDDLKSELTGNFEKVIVGLITPSTLYDVEELKKAMKGAGTDEGCLIEILASRSAEEIKNINITYRIKYGKSLEDDICSDTSFMFQRVLVSLAAGGRDQSTN--------------VNEALAKQDANELYEAGEKKWGTDEVKFLTILCSRNRNHLLKVFDEYKKIAKKDLEASIKSEMSGHFEDALLAVVKCLRSRPGYFAERLYKSMKGLGTDDKTLIRVMVSRCEIDMLEIRSEFKKMYGKSLHSFIKGDCSGDYRKVLLKLCGG 339          

HSP 2 Score: 64.3142 bits (155), Expect = 9.372e-11
Identity = 40/137 (29.20%), Postives = 71/137 (51.82%), Query Frame = 1
Query:  739 KKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN*D 1149
            K  GTDE   I +   R   Q +     Y+   GKD+ D + SE++G+ + V+  +   +     Y   +L K+MKGAGT++  L+ +L +RS  ++ NI   ++ ++  +LE+ +  DTS  ++  L+    G  D
Sbjct:   50 KGAGTDEDAIIDVIANRTLSQRQEIKTAYKTTIGKDLEDDLKSELTGNFEKVIVGLITPST---LYDVEELKKAMKGAGTDEGCLIEILASRSAEEIKNINITYRIKYGKSLEDDICSDTSFMFQRVLVSLAAGGRD 183          
BLAST of Annexin vs. Ensembl Xenopus
Match: trpv3 (transient receptor potential cation channel, subfamily V, member 3 [Source:Xenbase;Acc:XB-GENE-1013149])

HSP 1 Score: 296.204 bits (757), Expect = 8.913e-98
Identity = 152/322 (47.20%), Postives = 212/322 (65.84%), Query Frame = 1
Query:  160 KGTIKPFPNFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDLDYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLM 1125
            +GTIK  PNF+   D E LRKAMKG GTDE+AI++ +  R   QR +IK  +KT +GKDLI+ LKSE+SGN ++ +I       YYDA+SL+ AMKGAGT+E VL EIL +R+N +I+NI   YK  F  D+E+DI  +TSG F+R+L+S  Q N+ E  N              VN+ QA Q+A  LY AGE K+GTDE+ F  +   R+  QLRA  + Y +I+ +D+   I  E SG ++  LKA+   A+N+P +FA +LY+SMKGAGT+D+TL+R+++TRSEIDL+ IK+ + +    +L   +  DTSGDYR  L+
Sbjct:    7 QGTIKAAPNFDALSDAEKLRKAMKGFGTDEQAIVDVVANRSNDQRQKIKAAFKTAYGKDLIKDLKSELSGNVEELIIALFMPATYYDAWSLYHAMKGAGTQERVLIEILCTRTNSEIKNIVSCYKHEFGRDIEKDIRSDTSGHFERLLISMCQGNRDENQN--------------VNLQQAEQDAQRLYQAGEGKLGTDESSFNLVLASRSFPQLRAVAEAYARISKRDLISVIGREFSGYIEDGLKAVLQCAINRPAFFAERLYRSMKGAGTDDSTLIRIIVTRSEIDLVQIKQAYVQMHQKSLSAAISSDTSGDYRRLLI 314          

HSP 2 Score: 78.5666 bits (192), Expect = 1.216e-15
Identity = 43/137 (31.39%), Postives = 74/137 (54.01%), Query Frame = 1
Query:  739 KKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN*D 1149
            K  GTDE   + +   R+  Q +     ++   GKD+   + SE+SG+++ ++ A+   A    +Y A  LY +MKGAGT +  L+ +L TR+  ++ NI   ++ EF   +E  ++ DTSG +   L+   +GN D
Sbjct:   30 KGFGTDEQAIVDVVANRSNDQRQKIKAAFKTAYGKDLIKDLKSELSGNVEELIIALFMPAT---YYDAWSLYHAMKGAGTQERVLIEILCTRTNSEIKNIVSCYKHEFGRDIEKDIRSDTSGHFERLLISMCQGNRD 163          

HSP 3 Score: 66.6254 bits (161), Expect = 1.186e-11
Identity = 44/143 (30.77%), Postives = 73/143 (51.05%), Query Frame = 1
Query:  193 VEHDCEVLRKAMKG-IGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFK---KAVIESLYDLDYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVS 609
             E D + L +A +G +GTDE +    L  R   Q   + + Y  +  +DLI  +  E SG  +   KAV++   +   + A  L+ +MKGAGT ++ L  I+ +RS   +  IK  Y +     L   I  +TSG ++R+L++
Sbjct:  173 AEQDAQRLYQAGEGKLGTDESSFNLVLASRSFPQLRAVAEAYARISKRDLISVIGREFSGYIEDGLKAVLQCAINRPAFFAERLYRSMKGAGTDDSTLIRIIVTRSEIDLVQIKQAYVQMHQKSLSAAISSDTSGDYRRLLIA 315          
BLAST of Annexin vs. Ensembl Mouse
Match: Anxa7 (annexin A7 [Source:MGI Symbol;Acc:MGI:88031])

HSP 1 Score: 296.975 bits (759), Expect = 2.695e-96
Identity = 152/325 (46.77%), Postives = 214/325 (65.85%), Query Frame = 1
Query:  160 KGTIKPFPNFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDLDYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFV 1134
            +GTI P  NF+   D E+LRKAMKG GTDE+AI++ +  R   QR +IK  +KTM+GKDLI+ LKSE+SGN ++ ++       YYDA+SL +AM+GAGT+E VL EIL +R+N +I +I   Y+  F  DLE+DI  +TSG F+R+LVS  Q N+ E  +              VN   A+++A  LY AGE ++GTDE+ F  I   R+  QL+AT + Y ++A +D+  S+  E SG ++S LK I   A+N+P +FA +LY SMKGAGT+D+TLVR+++TRSEIDL+ IK+ F + +  TL   +  DTSGDYR  L+  V
Sbjct:  151 QGTILPASNFDAMRDAEILRKAMKGFGTDEQAIVDVVSNRSNDQRQQIKAAFKTMYGKDLIKDLKSELSGNMEELILALFMPSTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIRDIVRCYQLEFGRDLEKDIRSDTSGHFERLLVSMCQGNRDERQS--------------VNHQMAQEDAQRLYQAGEGRLGTDESCFNMILATRSFPQLKATMEAYSRMANRDLLSSVSREFSGYVESGLKTILQCALNRPAFFAERLYYSMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFTQMYQKTLSTMIASDTSGDYRKLLLAIV 461          

HSP 2 Score: 78.5666 bits (192), Expect = 2.486e-15
Identity = 44/146 (30.14%), Postives = 79/146 (54.11%), Query Frame = 1
Query:  718 ELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN*DSR 1155
            E+     K  GTDE   + +   R+  Q +     ++ + GKD+   + SE+SG+++ ++ A+   +    +Y A  L K+M+GAGT +  L+ +L TR+  ++ +I + +Q EF   LE  ++ DTSG +   L+   +GN D R
Sbjct:  167 EILRKAMKGFGTDEQAIVDVVSNRSNDQRQQIKAAFKTMYGKDLIKDLKSELSGNMEELILALFMPST---YYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIRDIVRCYQLEFGRDLEKDIRSDTSGHFERLLVSMCQGNRDER 309          
BLAST of Annexin vs. Ensembl Mouse
Match: Anxa7 (annexin A7 [Source:MGI Symbol;Acc:MGI:88031])

HSP 1 Score: 296.975 bits (759), Expect = 2.695e-96
Identity = 152/325 (46.77%), Postives = 214/325 (65.85%), Query Frame = 1
Query:  160 KGTIKPFPNFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDLDYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFV 1134
            +GTI P  NF+   D E+LRKAMKG GTDE+AI++ +  R   QR +IK  +KTM+GKDLI+ LKSE+SGN ++ ++       YYDA+SL +AM+GAGT+E VL EIL +R+N +I +I   Y+  F  DLE+DI  +TSG F+R+LVS  Q N+ E  +              VN   A+++A  LY AGE ++GTDE+ F  I   R+  QL+AT + Y ++A +D+  S+  E SG ++S LK I   A+N+P +FA +LY SMKGAGT+D+TLVR+++TRSEIDL+ IK+ F + +  TL   +  DTSGDYR  L+  V
Sbjct:  151 QGTILPASNFDAMRDAEILRKAMKGFGTDEQAIVDVVSNRSNDQRQQIKAAFKTMYGKDLIKDLKSELSGNMEELILALFMPSTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIRDIVRCYQLEFGRDLEKDIRSDTSGHFERLLVSMCQGNRDERQS--------------VNHQMAQEDAQRLYQAGEGRLGTDESCFNMILATRSFPQLKATMEAYSRMANRDLLSSVSREFSGYVESGLKTILQCALNRPAFFAERLYYSMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFTQMYQKTLSTMIASDTSGDYRKLLLAIV 461          

HSP 2 Score: 78.5666 bits (192), Expect = 2.486e-15
Identity = 44/146 (30.14%), Postives = 79/146 (54.11%), Query Frame = 1
Query:  718 ELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN*DSR 1155
            E+     K  GTDE   + +   R+  Q +     ++ + GKD+   + SE+SG+++ ++ A+   +    +Y A  L K+M+GAGT +  L+ +L TR+  ++ +I + +Q EF   LE  ++ DTSG +   L+   +GN D R
Sbjct:  167 EILRKAMKGFGTDEQAIVDVVSNRSNDQRQQIKAAFKTMYGKDLIKDLKSELSGNMEELILALFMPST---YYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIRDIVRCYQLEFGRDLEKDIRSDTSGHFERLLVSMCQGNRDER 309          
BLAST of Annexin vs. Ensembl Mouse
Match: Anxa7 (annexin A7 [Source:MGI Symbol;Acc:MGI:88031])

HSP 1 Score: 297.36 bits (760), Expect = 3.066e-96
Identity = 158/359 (44.01%), Postives = 223/359 (62.12%), Query Frame = 1
Query:   58 YSVSIKDLPSSEFIIIKPLSSR*MDQIGVKGERYKGTIKPFPNFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDLDYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFV 1134
            Y   I    SS +    P+S           +  +GTI P  NF+   D E+LRKAMKG GTDE+AI++ +  R   QR +IK  +KTM+GKDLI+ LKSE+SGN ++ ++       YYDA+SL +AM+GAGT+E VL EIL +R+N +I +I   Y+  F  DLE+DI  +TSG F+R+LVS  Q N+ E  +              VN   A+++A  LY AGE ++GTDE+ F  I   R+  QL+AT + Y ++A +D+  S+  E SG ++S LK I   A+N+P +FA +LY SMKGAGT+D+TLVR+++TRSEIDL+ IK+ F + +  TL   +  DTSGDYR  L+  V
Sbjct:  139 YPSQINTESSSSYPAFPPVSLDYSSDPASMTQGTQGTILPASNFDAMRDAEILRKAMKGFGTDEQAIVDVVSNRSNDQRQQIKAAFKTMYGKDLIKDLKSELSGNMEELILALFMPSTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIRDIVRCYQLEFGRDLEKDIRSDTSGHFERLLVSMCQGNRDERQS--------------VNHQMAQEDAQRLYQAGEGRLGTDESCFNMILATRSFPQLKATMEAYSRMANRDLLSSVSREFSGYVESGLKTILQCALNRPAFFAERLYYSMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFTQMYQKTLSTMIASDTSGDYRKLLLAIV 483          

HSP 2 Score: 78.9518 bits (193), Expect = 2.059e-15
Identity = 44/147 (29.93%), Postives = 79/147 (53.74%), Query Frame = 1
Query:  715 TELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN*DSR 1155
             E+     K  GTDE   + +   R+  Q +     ++ + GKD+   + SE+SG+++ ++ A+   +    +Y A  L K+M+GAGT +  L+ +L TR+  ++ +I + +Q EF   LE  ++ DTSG +   L+   +GN D R
Sbjct:  188 AEILRKAMKGFGTDEQAIVDVVSNRSNDQRQQIKAAFKTMYGKDLIKDLKSELSGNMEELILALFMPST---YYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIRDIVRCYQLEFGRDLEKDIRSDTSGHFERLLVSMCQGNRDER 331          
BLAST of Annexin vs. Ensembl Mouse
Match: Anxa5 (annexin A5 [Source:MGI Symbol;Acc:MGI:106008])

HSP 1 Score: 281.182 bits (718), Expect = 3.908e-92
Identity = 146/330 (44.24%), Postives = 210/330 (63.64%), Query Frame = 1
Query:  160 KGTIKPFPNFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDLDYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN*D 1149
            +GT+  FP F+   D EVLRKAMKG+GTDE +I+  L  R  AQR EI + +KT+FG+DL++ LKSE++G F+K ++  +     YDA+ L  A+KGAGT E VLTEI+ SR+  ++  IK +Y++ +  +LE D++ +TSG+++R+LV  LQAN              R     ++  Q   +A  L+ AGE K GTDE  FI IF  R+   LR  FD+Y  I+G  I ++ID E SG+L+ +L A+     + P Y A  LY +MKGAGT+D TL+RV+++RSEIDL NI+KEF++ F  +L + +K DTSGDY+  L+    G  D
Sbjct:    4 RGTVTDFPGFDGRADAEVLRKAMKGLGTDEDSILNLLTSRSNAQRQEIAQEFKTLFGRDLVDDLKSELTGKFEKLIVAMMKPSRLYDAYELKHALKGAGTDEKVLTEIIASRTPEELSAIKQVYEEEYGSNLEDDVVGDTSGYYQRMLVVLLQAN--------------RDPDTAIDDAQVELDAQALFQAGELKWGTDEEKFITIFGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVVVSRSEIDLFNIRKEFRKNFATSLYSMIKGDTSGDYKKALLLLCGGEDD 319          
BLAST of Annexin vs. Ensembl Mouse
Match: Anxa4 (annexin A4 [Source:MGI Symbol;Acc:MGI:88030])

HSP 1 Score: 279.641 bits (714), Expect = 1.761e-91
Identity = 150/327 (45.87%), Postives = 200/327 (61.16%), Query Frame = 1
Query:  163 GTIKPFPNFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDLDYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN 1143
            GT+K    FN   D + LRKAMKG+GTDE AII  L  R  AQR EI+  YK+  G+DLIE LKSE+S NF++ ++  +     YD   L  AMKGAGT E  L EIL SR+  +I  I   Y++ +   LE+DI  +TS  F+RVLVS   A + E                 ++    +Q+A ELY AGEK+ GTDE  F+ I C RN+  L   FDEY++I+ KDI  SI SE SG  +  L AI     +KP YFA +LYKSMKG GT+D TL+RV+++R+EID+L+I+  F+R +  +L +F+K DTSGDYR  L+    G+
Sbjct:    6 GTVKAASGFNATEDAQTLRKAMKGLGTDEDAIIGILAYRNTAQRQEIRSAYKSTIGRDLIEDLKSELSSNFEQVILGLMTPTVLYDVQELRRAMKGAGTDEGCLIEILASRTPEEIRRINQTYQQQYGRSLEEDICSDTSFMFQRVLVSLSAAGRDE--------------GNYLDDALMKQDAQELYEAGEKRWGTDEVKFLSILCSRNRNHLLHVFDEYKRISQKDIEQSIKSETSGSFEDALLAIVKCMRSKPSYFAERLYKSMKGLGTDDNTLIRVMVSRAEIDMLDIRASFKRLYGKSLYSFIKGDTSGDYRKVLLVLCGGD 318          
BLAST of Annexin vs. UniProt/SwissProt
Match: sp|P20072|ANXA7_BOVIN (Annexin A7 OS=Bos taurus OX=9913 GN=ANXA7 PE=1 SV=2)

HSP 1 Score: 301.982 bits (772), Expect = 1.904e-97
Identity = 156/324 (48.15%), Postives = 214/324 (66.05%), Query Frame = 1
Query:  163 GTIKPFPNFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDLDYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFV 1134
            GTI+P  NF+   D EVLRKAMKG GTDE+AII+ +  R   QR +IK  +KTM+GKDLI+ LKSE+SGN ++ ++       YYDA+SL  AMKGAGT+E VL EIL +R+N +I  I   Y+  F  DLE+DI  +TSG F+R+LVS  Q N+ E  N              VN   A+++A  LY AGE ++GTDE+ F  I   R+  QL+AT + Y ++A +D+ +S+  E SG+++S LK I   A+N+P +FA +LY SMKGAGT+D+TLVR+++TRSEIDL+ IK+ F + +  TL   +  DTSGDYR  L+  V
Sbjct:  152 GTIRPAANFDAMRDAEVLRKAMKGFGTDEQAIIDVVANRSNDQRQKIKAAFKTMYGKDLIKDLKSELSGNMEELILALFMPSTYYDAWSLRNAMKGAGTQERVLIEILCTRTNQEIREIVRCYQSEFGRDLEKDIRSDTSGHFERLLVSMCQGNRDENQN--------------VNHQLAQEDAQRLYQAGEGRLGTDESCFNMILATRSFPQLKATMEAYSRMANRDLLNSVSREFSGNVESGLKTILQCALNRPAFFAERLYYSMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFSQMYQKTLGTMIASDTSGDYRKLLLAIV 461          

HSP 2 Score: 77.0258 bits (188), Expect = 5.338e-14
Identity = 43/137 (31.39%), Postives = 74/137 (54.01%), Query Frame = 1
Query:  739 KKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN*D 1149
            K  GTDE   I +   R+  Q +     ++ + GKD+   + SE+SG+++ ++ A+   +    +Y A  L  +MKGAGT +  L+ +L TR+  ++  I + +Q EF   LE  ++ DTSG +   L+   +GN D
Sbjct:  174 KGFGTDEQAIIDVVANRSNDQRQKIKAAFKTMYGKDLIKDLKSELSGNMEELILALFMPST---YYDAWSLRNAMKGAGTQERVLIEILCTRTNQEIREIVRCYQSEFGRDLEKDIRSDTSGHFERLLVSMCQGNRD 307          
BLAST of Annexin vs. UniProt/SwissProt
Match: sp|Q07076|ANXA7_MOUSE (Annexin A7 OS=Mus musculus OX=10090 GN=Anxa7 PE=1 SV=2)

HSP 1 Score: 296.975 bits (759), Expect = 1.885e-95
Identity = 152/325 (46.77%), Postives = 214/325 (65.85%), Query Frame = 1
Query:  160 KGTIKPFPNFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDLDYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFV 1134
            +GTI P  NF+   D E+LRKAMKG GTDE+AI++ +  R   QR +IK  +KTM+GKDLI+ LKSE+SGN ++ ++       YYDA+SL +AM+GAGT+E VL EIL +R+N +I +I   Y+  F  DLE+DI  +TSG F+R+LVS  Q N+ E  +              VN   A+++A  LY AGE ++GTDE+ F  I   R+  QL+AT + Y ++A +D+  S+  E SG ++S LK I   A+N+P +FA +LY SMKGAGT+D+TLVR+++TRSEIDL+ IK+ F + +  TL   +  DTSGDYR  L+  V
Sbjct:  151 QGTILPASNFDAMRDAEILRKAMKGFGTDEQAIVDVVSNRSNDQRQQIKAAFKTMYGKDLIKDLKSELSGNMEELILALFMPSTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIRDIVRCYQLEFGRDLEKDIRSDTSGHFERLLVSMCQGNRDERQS--------------VNHQMAQEDAQRLYQAGEGRLGTDESCFNMILATRSFPQLKATMEAYSRMANRDLLSSVSREFSGYVESGLKTILQCALNRPAFFAERLYYSMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFTQMYQKTLSTMIASDTSGDYRKLLLAIV 461          

HSP 2 Score: 78.5666 bits (192), Expect = 1.739e-14
Identity = 44/146 (30.14%), Postives = 79/146 (54.11%), Query Frame = 1
Query:  718 ELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN*DSR 1155
            E+     K  GTDE   + +   R+  Q +     ++ + GKD+   + SE+SG+++ ++ A+   +    +Y A  L K+M+GAGT +  L+ +L TR+  ++ +I + +Q EF   LE  ++ DTSG +   L+   +GN D R
Sbjct:  167 EILRKAMKGFGTDEQAIVDVVSNRSNDQRQQIKAAFKTMYGKDLIKDLKSELSGNMEELILALFMPST---YYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIRDIVRCYQLEFGRDLEKDIRSDTSGHFERLLVSMCQGNRDER 309          
BLAST of Annexin vs. UniProt/SwissProt
Match: sp|P20073|ANXA7_HUMAN (Annexin A7 OS=Homo sapiens OX=9606 GN=ANXA7 PE=1 SV=3)

HSP 1 Score: 294.664 bits (753), Expect = 3.130e-94
Identity = 155/349 (44.41%), Postives = 222/349 (63.61%), Query Frame = 1
Query:   88 SEFIIIKPLSSR*MDQIGVKGERYKGTIKPFPNFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDLDYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFV 1134
            S + +  P+S     +     +  +GTI+P  NF+   D E+LRKAMKG GTDE+AI++ +  R   QR +IK  +KT +GKDLI+ LKSE+SGN ++ ++       YYDA+SL +AM+GAGT+E VL EIL +R+N +I  I   Y+  F  DLE+DI  +TSG F+R+LVS  Q N+ E  N+ I            N   A+++A  LY AGE ++GTDE+ F  I   R+  QLRAT + Y ++A +D+  S+  E SG ++S LK I   A+N+P +FA +LY +MKGAGT+D+TLVR+++TRSEIDL+ IK+ F + +  TL   +  DTSGDYR  L+  V
Sbjct:  152 SSYPVFSPVSLDYSSEPATVTQVTQGTIRPAANFDAIRDAEILRKAMKGFGTDEQAIVDVVANRSNDQRQKIKAAFKTSYGKDLIKDLKSELSGNMEELILALFMPPTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIREIVRCYQSEFGRDLEKDIRSDTSGHFERLLVSMCQGNRDE--NQSI------------NHQMAQEDAQRLYQAGEGRLGTDESCFNMILATRSFPQLRATMEAYSRMANRDLLSSVSREFSGYVESGLKTILQCALNRPAFFAERLYYAMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFAQMYQKTLGTMIAGDTSGDYRRLLLAIV 486          

HSP 2 Score: 76.6406 bits (187), Expect = 7.632e-14
Identity = 47/167 (28.14%), Postives = 83/167 (49.70%), Query Frame = 1
Query:  649 IREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN*D 1149
            + +V +  I    N +  R    E+     K  GTDE   + +   R+  Q +     ++   GKD+   + SE+SG+++ ++ A+        +Y A  L K+M+GAGT +  L+ +L TR+  ++  I + +Q EF   LE  ++ DTSG +   L+   +GN D
Sbjct:  171 VTQVTQGTIRPAANFDAIRD--AEILRKAMKGFGTDEQAIVDVVANRSNDQRQKIKAAFKTSYGKDLIKDLKSELSGNMEELILALFMPPT---YYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIREIVRCYQSEFGRDLEKDIRSDTSGHFERLLVSMCQGNRD 332          
BLAST of Annexin vs. UniProt/SwissProt
Match: sp|Q4R5L5|ANXA7_MACFA (Annexin A7 OS=Macaca fascicularis OX=9541 GN=ANXA7 PE=2 SV=1)

HSP 1 Score: 294.278 bits (752), Expect = 4.324e-94
Identity = 154/357 (43.14%), Postives = 225/357 (63.03%), Query Frame = 1
Query:   64 VSIKDLPSSEFIIIKPLSSR*MDQIGVKGERYKGTIKPFPNFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDLDYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFV 1134
            ++ +  PS  + +  P+S     +     +  +GTI+P  NF+   D E+LRKAMKG GTDE+AI++ +  R   QR +IK  +KT +GKDLI+ LKSE+SGN ++ ++       YYDA++L +AM+GAGT+E VL EIL +R+N +I  I   Y+  F  DLE+DI  +TSG F+R+LVS  Q N+ E              +  VN   A+++A  LY AGE ++GTDE+ F  I   R+  QLRAT + Y ++A +D+  S+  E SG ++S LK I   A+N+P +FA +LY +MKGAGT+D+TLVR+++TRSEIDL+ IK+ F + +  TL   +  DTSGDYR  L+  V
Sbjct:  146 INTESFPS--YPVFSPVSLDYSSEPAAMTQGTQGTIRPAANFDAMRDAEILRKAMKGFGTDEQAIVDVVANRSNDQRQKIKAAFKTSYGKDLIKDLKSELSGNMEELILALFMPPTYYDAWTLRKAMQGAGTQERVLIEILCTRTNQEIREIVRCYQSEFGRDLEKDIRSDTSGHFERLLVSMCQGNRDE--------------NQSVNHQMAQEDAQRLYQAGEGRLGTDESCFNMILATRSFPQLRATMEAYSRMANRDLLSSVSREFSGYVESGLKTILQCALNRPAFFAERLYYAMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFAQMYQKTLGTMIAGDTSGDYRRPLLAIV 486          

HSP 2 Score: 75.0998 bits (183), Expect = 2.436e-13
Identity = 42/137 (30.66%), Postives = 73/137 (53.28%), Query Frame = 1
Query:  739 KKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN*D 1149
            K  GTDE   + +   R+  Q +     ++   GKD+   + SE+SG+++ ++ A+        +Y A  L K+M+GAGT +  L+ +L TR+  ++  I + +Q EF   LE  ++ DTSG +   L+   +GN D
Sbjct:  199 KGFGTDEQAIVDVVANRSNDQRQKIKAAFKTSYGKDLIKDLKSELSGNMEELILALFMPPT---YYDAWTLRKAMQGAGTQERVLIEILCTRTNQEIREIVRCYQSEFGRDLEKDIRSDTSGHFERLLVSMCQGNRD 332          
BLAST of Annexin vs. UniProt/SwissProt
Match: sp|Q4R4H7|ANXA5_MACFA (Annexin A5 OS=Macaca fascicularis OX=9541 GN=ANXA5 PE=2 SV=3)

HSP 1 Score: 284.263 bits (726), Expect = 1.881e-92
Identity = 147/327 (44.95%), Postives = 210/327 (64.22%), Query Frame = 1
Query:  160 KGTIKPFPNFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDLDYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEG 1140
            +GT+  FP F+   D E LRKAMKG+GTDE++I+  L  R  AQR EI   +KT+FG+DL++ LKSE++G F+K ++  +     YDA+ L  A+KGAGT E VLTEI+ SR+  ++  IK +Y++ +   LE D++ +TSG+++R+LV  LQAN              R   A ++  Q  Q+A  L+ AGE K GTDE  FI IF  R+   LR  FD+Y  I+G  I ++ID E SG+L+ +L A+     + P Y A  LY +MKGAGT+D TL+RV+++RSEIDLLNI+KEF++ F  +L + +K DTSGDY+  L+    G
Sbjct:    6 RGTVTDFPGFDERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEISAAFKTLFGRDLLDDLKSELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTDEKVLTEIIASRTPEELRAIKEVYEEEYGSSLEDDVVGDTSGYYQRMLVVLLQAN--------------RDPDAGIDEAQVEQDAQALFQAGELKWGTDEEKFITIFGTRSVSHLRKVFDKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVMVSRSEIDLLNIRKEFRKNFATSLYSMIKGDTSGDYKKALLLLCGG 318          

HSP 2 Score: 70.4774 bits (171), Expect = 3.401e-12
Identity = 41/139 (29.50%), Postives = 78/139 (56.12%), Query Frame = 1
Query:  739 KKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKP--FYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN*D 1149
            K +GTDE   + +   R+  Q +     ++ + G+D+ D + SE++G  + ++ A+      KP   Y A +L  ++KGAGT++  L  ++ +R+  +L  IK+ ++ E+  +LE+ V  DTSG Y+  L+  ++ N D
Sbjct:   29 KGLGTDEESILTLLTSRSNAQRQEISAAFKTLFGRDLLDDLKSELTGKFEKLIVALM-----KPSRLYDAYELKHALKGAGTDEKVLTEIIASRTPEELRAIKEVYEEEYGSSLEDDVVGDTSGYYQRMLVVLLQANRD 162          
BLAST of Annexin vs. TrEMBL
Match: A0A1S3JHE8 (Annexin OS=Lingula unguis OX=7574 GN=LOC106173262 PE=3 SV=1)

HSP 1 Score: 352.829 bits (904), Expect = 9.216e-113
Identity = 170/339 (50.15%), Postives = 242/339 (71.39%), Query Frame = 1
Query:  133 QIGVKGERYKGTIKP--FPNFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDLDYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN 1143
            +IG   E++ GTI P  + +F+ E D EVLRKAMKG+GTDE+AII  L +R   QR EI+K +KTM+GKDLI  L+SE+SG+ K+A++       YYDA+SLH AM G GT+E+VL EIL +R+N QI+ I   YK  F  DLE+DI+ +TSG FKR+L+SC Q N+ ELT+ Q ++V   G  AV++   AR++A EL+ AGEK++GTDE+ F++I   RN YQ+RATF+EY K++G DI  +I SEMSG L+    A+     ++P +FATKL+K+M+G GT+D+TL+R++++RSE+DL NIK+ F R++   L   V+ +TSGDYR  ++  + GN
Sbjct:  289 KIGGTAEQFVGTIHPANYMSFSAEKDAEVLRKAMKGLGTDEQAIIGVLSKRSNQQRQEIEKMFKTMYGKDLIRELESELSGDLKEAIMGLFKPNAYYDAWSLHNAMVGLGTKESVLIEILCTRTNAQIKQIVQAYKDHFKRDLERDIMDDTSGHFKRLLISCCQGNRAELTDAQWQQVFSSGPEAVIDRALARRDAEELFRAGEKQLGTDESTFLRIMATRNYYQMRATFEEYAKVSGHDILQAISSEMSGSLEDAFTALVMSCRDRPEFFATKLHKAMQGLGTDDSTLIRIIVSRSEVDLQNIKQAFLRKYGKPLMKMVEGETSGDYRRLMLALIGGN 627          
BLAST of Annexin vs. TrEMBL
Match: A0A1S3JHA6 (Annexin OS=Lingula unguis OX=7574 GN=LOC106173262 PE=3 SV=1)

HSP 1 Score: 353.599 bits (906), Expect = 1.683e-112
Identity = 170/339 (50.15%), Postives = 242/339 (71.39%), Query Frame = 1
Query:  133 QIGVKGERYKGTIKP--FPNFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDLDYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN 1143
            +IG   E++ GTI P  + +F+ E D EVLRKAMKG+GTDE+AII  L +R   QR EI+K +KTM+GKDLI  L+SE+SG+ K+A++       YYDA+SLH AM G GT+E+VL EIL +R+N QI+ I   YK  F  DLE+DI+ +TSG FKR+L+SC Q N+ ELT+ Q ++V   G  AV++   AR++A EL+ AGEK++GTDE+ F++I   RN YQ+RATF+EY K++G DI  +I SEMSG L+    A+     ++P +FATKL+K+M+G GT+D+TL+R++++RSE+DL NIK+ F R++   L   V+ +TSGDYR  ++  + GN
Sbjct:  329 KIGGTAEQFVGTIHPANYMSFSAEKDAEVLRKAMKGLGTDEQAIIGVLSKRSNQQRQEIEKMFKTMYGKDLIRELESELSGDLKEAIMGLFKPNAYYDAWSLHNAMVGLGTKESVLIEILCTRTNAQIKQIVQAYKDHFKRDLERDIMDDTSGHFKRLLISCCQGNRAELTDAQWQQVFSSGPEAVIDRALARRDAEELFRAGEKQLGTDESTFLRIMATRNYYQMRATFEEYAKVSGHDILQAISSEMSGSLEDAFTALVMSCRDRPEFFATKLHKAMQGLGTDDSTLIRIIVSRSEVDLQNIKQAFLRKYGKPLMKMVEGETSGDYRRLMLALIGGN 667          
BLAST of Annexin vs. TrEMBL
Match: A0A2T7PZC2 (Annexin OS=Pomacea canaliculata OX=400727 GN=C0Q70_01396 PE=3 SV=1)

HSP 1 Score: 350.517 bits (898), Expect = 1.783e-112
Identity = 169/338 (50.00%), Postives = 240/338 (71.01%), Query Frame = 1
Query:  127 MDQIGVKG--ERYKGTIKPFPNFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDLDYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFV 1134
            +D++ + G  + ++ T+   PNF+ E D E LRK+MKG GTDE+ II  +G+RC  QR EI K YKTM+G+DLI  L+SE+SGNF++ ++       YYDA+SL+ AM+G GT+E+VL EIL +RSN QI +I   YK+ F  DLE+DI  +TSG FK++L+SC Q N+ ELT EQ+ +V+ +G SAVVN   ARQ+A +L  AG K +GTDE+ FI +  +R+ YQL+ATF EY+K+ GKDI DSI SE SGD ++ L+AI   A N+P YFA KL+ S+KG GT+D+ L+R++++R EIDL +IK  +  ++  TL++ V  DTSGDY+  L+  +
Sbjct:  233 LDRVTLDGCAQIFRPTVVASPNFSAERDSETLRKSMKGAGTDERTIIGIIGKRCNTQRQEIAKIYKTMYGRDLIADLESELSGNFRETIMGMFKPPAYYDAWSLNHAMEGLGTKESVLIEILCTRSNQQIRDIVACYKEHFKRDLEKDISDDTSGHFKKLLISCCQGNRQELTPEQLSQVRSQGASAVVNAELARQDAQKLQEAGIKHLGTDESTFISVLALRHMYQLQATFSEYQKLTGKDILDSISSETSGDFETGLRAIVRSAKNRPEYFADKLHDSIKGLGTDDSRLIRIIVSRCEIDLQDIKDAYLTKYQKTLDSEVASDTSGDYKRILLALI 570          

HSP 2 Score: 70.4774 bits (171), Expect = 2.356e-9
Identity = 44/157 (28.03%), Postives = 77/157 (49.04%), Query Frame = 1
Query:  676 SAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYF-ATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN 1143
            + V + N + +  +E      K  GTDE   I I   R   Q +     Y+ + G+D+   ++SE+SG+ +  +  +       P Y+ A  L  +M+G GT ++ L+ +L TRS   + +I   ++  F   LE  + DDTSG ++  L+   +GN
Sbjct:  248 TVVASPNFSAERDSETLRKSMKGAGTDERTIIGIIGKRCNTQRQEIAKIYKTMYGRDLIADLESELSGNFRETIMGM----FKPPAYYDAWSLNHAMEGLGTKESVLIEILCTRSNQQIRDIVACYKEHFKRDLEKDISDDTSGHFKKLLISCCQGN 400          
BLAST of Annexin vs. TrEMBL
Match: F2UPY8 (Annexin OS=Salpingoeca rosetta (strain ATCC 50818 / BSB-021) OX=946362 GN=PTSG_10801 PE=3 SV=1)

HSP 1 Score: 331.257 bits (848), Expect = 3.232e-105
Identity = 165/324 (50.93%), Postives = 225/324 (69.44%), Query Frame = 1
Query:  166 TIKPFPNFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDLDYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVE 1137
            T+ P+PNFN E D   LRKAMKG+GTDEKAII+ L  R   QRL+IK  +KTM+GKDL + LKSE SG+F+  ++  LYD  ++DA  L +AMKG GT E  L E++ +R+N +I  IK  YK+ +  DLE+DI+ +TSG FKR+LVSC+Q N+ E              SA V++ +A++EA ELY AGEK+ GTDE+ F +I  +R+  QLRATF EY KI+  DI  SI+ EMSGDL+S  KA+     ++P YFA +LYK+MKGAGT+D TLVR++++RSE+D++ IK+ F   +N +L   +KDDTSGDYR  L+  V+
Sbjct:  246 TVHPYPNFNAEEDAIALRKAMKGMGTDEKAIIDVLTNRTAEQRLKIKLQFKTMYGKDLEKDLKSETSGHFEDVLVGLLYDRPHFDARCLRKAMKGMGTDERALIEVICTRTNQEIHAIKAAYKELYGRDLEKDIVSDTSGHFKRLLVSCVQGNREE--------------SAEVDMAKAKREAEELYKAGEKRWGTDESKFNQIIALRSYPQLRATFQEYRKISSYDIVRSIEHEMSGDLKSAFKAVVMCIKDRPNYFAERLYKAMKGAGTDDETLVRIVVSRSEVDMVEIKERFFDTYNKSLAKMIKDDTSGDYRRILIALVK 555          

HSP 2 Score: 71.2478 bits (173), Expect = 1.573e-9
Identity = 49/165 (29.70%), Postives = 83/165 (50.30%), Query Frame = 1
Query:  649 IREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN 1143
            +  V    +    N N A ++A  L  A  K +GTDE   I +   R   Q      +++ + GKD+   + SE SG  + VL  + +   ++P + A  L K+MKG GT++  L+ V+ TR+  ++  IK  ++  +   LE  +  DTSG ++  L+  V+GN
Sbjct:  239 LEPVGHPTVHPYPNFN-AEEDAIALRKA-MKGMGTDEKAIIDVLTNRTAEQRLKIKLQFKTMYGKDLEKDLKSETSGHFEDVLVGLLY---DRPHFDARCLRKAMKGMGTDERALIEVICTRTNQEIHAIKAAYKELYGRDLEKDIVSDTSGHFKRLLVSCVQGN 398          
BLAST of Annexin vs. TrEMBL
Match: A0A210QSV8 (Annexin OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT05600 PE=3 SV=1)

HSP 1 Score: 333.183 bits (853), Expect = 3.817e-105
Identity = 168/335 (50.15%), Postives = 229/335 (68.36%), Query Frame = 1
Query:  139 GVKGERYKGTIKPFPNFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDLDYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN 1143
            G +GE  + T++P   F+ E D E+LRKAMKG GTDEKAII  +  R   QR +I   +KTM+GKDLI  LKSE+SG+ ++ ++       Y+DA+SLH+AM   GT+E VL EIL +RSN +I+ I   YKK F+  LEQDI  ETSG FKR+L+SC Q N+ ELT +Q + +  +G+  VV+   A+Q+A +LY AGEK IGTDE+ F+ +  +RN YQLRATF EY+KI+GKDI  S+ SE SGD++   KA+   A+N+P YFA  L+KSM G GT D+TL+R++++RSEIDL +IK+E+    + TL   V  DT GDY   L+  + GN
Sbjct:  293 GGQGEVARPTVRPAKPFSPEQDAEILRKAMKGFGTDEKAIISVISARTNQQRQQILTMFKTMYGKDLIADLKSELSGDLEELIMGMFKPTTYFDAWSLHKAMTCVGTKEAVLIEILCTRSNAEIKEIVECYKKHFSRSLEQDISSETSGHFKRLLISCCQGNRNELTPDQQQRLAYQGLEGVVDRALAQQDAQKLYQAGEKMIGTDESAFLTVMAVRNHYQLRATFQEYQKISGKDILKSVKSEFSGDVEDGFKALISSAMNRPKYFADLLHKSMAGLGTKDSTLIRIIVSRSEIDLQDIKEEYLVHHHKTLRTAVAGDTRGDYEKLLLALI-GN 626          
BLAST of Annexin vs. Ensembl Cavefish
Match: ENSAMXT00000004530.2 (annexin A11-like [Source:NCBI gene;Acc:103040502])

HSP 1 Score: 295.434 bits (755), Expect = 1.355e-95
Identity = 156/329 (47.42%), Postives = 210/329 (63.83%), Query Frame = 1
Query:  157 YKGTIKPFPNFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDLDYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN 1143
            ++GTIK +P  +   D EVLRKAMKG GTDE AIIE LG R   QR  + + YKT +GKDLI  LKSE++GNF+  V+  +     YDA+ LH ++ GAGT E  L EIL+SRSN +I  I  +YK  +   LE  I  +TSG F+R+LVS  Q N+ E      RE         V++  A+Q+A +LY AGE K+GTDE+ F  I C R+K  LR  F EY+++ GKDI  SI  EMSGDL+  L A+     N P YFA +L K+MKGAGT D TL+R+++TRSE+D+L+I++E+ R F  +L   +  DTSGDY+  L++   G+
Sbjct:  166 FRGTIKDYPGADPLRDVEVLRKAMKGFGTDENAIIELLGNRSGKQRAPLVRAYKTTYGKDLISDLKSELTGNFEALVLAMVKGPAEYDAYELHSSIAGAGTDEACLIEILSSRSNAEIREINQIYKTEYKKTLEDAIQHDTSGHFRRLLVSLCQGNRDE------RE--------TVDVALAKQDAQKLYAAGENKLGTDESQFNAILCARSKPHLRQVFQEYQQMCGKDIEKSICREMSGDLERGLLAVVKCLKNTPGYFAERLNKAMKGAGTKDRTLIRIMVTRSEVDMLDIRQEYIRNFGKSLYTDISSDTSGDYKKLLLKLCGGS 480          

HSP 2 Score: 80.4925 bits (197), Expect = 4.464e-16
Identity = 45/140 (32.14%), Postives = 79/140 (56.43%), Query Frame = 1
Query:  739 KKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPF-YFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN*DSR 1155
            K  GTDE   I++   R+  Q       Y+   GKD+   + SE++G+ ++++ A+    V  P  Y A +L+ S+ GAGT++  L+ +L +RS  ++  I + ++ E+  TLE+ ++ DTSG +R  L+   +GN D R
Sbjct:  190 KGFGTDENAIIELLGNRSGKQRAPLVRAYKTTYGKDLISDLKSELTGNFEALVLAM----VKGPAEYDAYELHSSIAGAGTDEACLIEILSSRSNAEIREINQIYKTEYKKTLEDAIQHDTSGHFRRLLVSLCQGNRDER 325          
BLAST of Annexin vs. Ensembl Cavefish
Match: anxa4 (annexin A4 [Source:NCBI gene;Acc:103027730])

HSP 1 Score: 284.648 bits (727), Expect = 1.978e-93
Identity = 151/324 (46.60%), Postives = 202/324 (62.35%), Query Frame = 1
Query:  160 KGTIKPFPNFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDLDYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRF 1131
            +GT+     FN + D E LRKAMKG GTDE AII  L  R +AQR  IK++YK   GK+L + LKSE++GNF+K VI  L     YDA+ L  A+KGAGT E  L EIL SR+  ++  +   Y K +   LE D+  +TSG FKRVLVS L A + E              S  V+   A Q+A E+Y AGE   GTDE  F+ + C+RN+  L   F+EY++I+G+DI DSI  EMSG L+ V  AI     +KP +FA +L+KSMKG GT D+ L+RV+++RSEID+ +IK EF + +  +L +F+K DTSGDYR  L+  
Sbjct:    7 RGTVTEAAGFNPDQDAEALRKAMKGAGTDEAAIISILPHRTIAQRQLIKESYKRAVGKELADDLKSELTGNFEKVVIGLLMTAPVYDAYELRNAIKGAGTDEACLIEILASRTISEMRTLVATYNKEYGKSLEDDVCGDTSGMFKRVLVSLLTAGRDE--------------SNTVDQALAAQDAKEIYEAGEAHWGTDEVKFLTVLCVRNRNHLLKVFEEYKRISGRDIEDSIKREMSGCLEEVFLAIVRCIKSKPGFFAERLHKSMKGLGTTDSILIRVMVSRSEIDMQDIKAEFLKTYGKSLHSFIKGDTSGDYRKILLEL 316          

HSP 2 Score: 74.3294 bits (181), Expect = 2.204e-14
Identity = 45/148 (30.41%), Postives = 80/148 (54.05%), Query Frame = 1
Query:  706 QEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN*D 1149
            Q+A  L  A  K  GTDEA  I I   R   Q +   + Y++  GK++ D + SE++G+ + V+  +   A   P Y A +L  ++KGAGT++  L+ +L +R+  ++  +   + +E+  +LE+ V  DTSG ++  L+  +    D
Sbjct:   20 QDAEALRKA-MKGAGTDEAAIISILPHRTIAQRQLIKESYKRAVGKELADDLKSELTGNFEKVVIGLLMTA---PVYDAYELRNAIKGAGTDEACLIEILASRTISEMRTLVATYNKEYGKSLEDDVCGDTSGMFKRVLVSLLTAGRD 163          
BLAST of Annexin vs. Ensembl Cavefish
Match: anxa11a (annexin A11 [Source:NCBI gene;Acc:103039162])

HSP 1 Score: 288.886 bits (738), Expect = 1.774e-92
Identity = 150/329 (45.59%), Postives = 212/329 (64.44%), Query Frame = 1
Query:  157 YKGTIKPFPNFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDLDYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN 1143
            ++G+I   P  +   D EVLRKAMKG GTDE+AII  LG R   QR+ +  +YKT +GKDL++ LKSE+SGNF+K V+  L     YDA  L EA+KGAGT E  L EIL+SRSN +I  I  ++K  +   LE  I  +TSG F+R+LVS  Q N+ E  N              V+I  A+Q+A  LY AGE K+GTDE+ F  I C R+K  LRA F+EY+ + G+DI  SI+ EMSGDL++ + A+     + P YFA +LYK+MKG GT D TL+R++++RSE+D+L+I++ + +++  +L   +  DTSGDY+  L++   G+
Sbjct:  211 FRGSIPDCPGADPLKDAEVLRKAMKGFGTDEQAIINLLGSRSNKQRVPLLISYKTAYGKDLVKDLKSELSGNFEKLVLAMLKTPAQYDASELREAIKGAGTDEACLIEILSSRSNAEIREINQIFKAEYKKSLEDSISGDTSGHFRRLLVSLAQGNRDEREN--------------VDIALAKQDAQTLYQAGENKLGTDESKFNAILCARSKPHLRAVFNEYQHMCGRDIEKSIEREMSGDLENGMLAVVKCIKDTPTYFAERLYKAMKGLGTKDRTLIRIMVSRSEVDMLDIRQAYVKKYGKSLYTDISGDTSGDYKKLLLKLCGGS 525          

HSP 2 Score: 79.7221 bits (195), Expect = 9.219e-16
Identity = 44/139 (31.65%), Postives = 76/139 (54.68%), Query Frame = 1
Query:  739 KKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN*DSR 1155
            K  GTDE   I +   R+  Q       Y+   GKD+   + SE+SG+ + ++ A+         Y A++L +++KGAGT++  L+ +L +RS  ++  I + F+ E+  +LE+ +  DTSG +R  L+   +GN D R
Sbjct:  235 KGFGTDEQAIINLLGSRSNKQRVPLLISYKTAYGKDLVKDLKSELSGNFEKLVLAMLKTPAQ---YDASELREAIKGAGTDEACLIEILSSRSNAEIREINQIFKAEYKKSLEDSISGDTSGHFRRLLVSLAQGNRDER 370          
BLAST of Annexin vs. Ensembl Cavefish
Match: anxa5b (annexin A5-like [Source:NCBI gene;Acc:103025290])

HSP 1 Score: 275.789 bits (704), Expect = 4.016e-90
Identity = 150/328 (45.73%), Postives = 202/328 (61.59%), Query Frame = 1
Query:  160 KGTIKPFPNFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDLDYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN 1143
            +GT+KP   F+   D EVL KAMKG+GTDE  I++ L  R  AQR +IK  YKT+ GKDL+  LKSE+ G F+  V+  +     +D  +L  A+KGAGT E  L EIL SR+ ++I  I   YK+ ++H+LE D+  +TSG FKRVLV  LQAN+ +                 V     + +A  L+NAGEKK GTDE  FI I   R+   LR  FD Y K++G  I +SI  E SG L+ VL AI   A + P YFA  LY SMKGAGT+D TL+R++++RSEIDLL+I+ EF++ F  +L   +++DTSGDYR  L+    G+
Sbjct:    4 RGTVKPQSGFDANKDAEVLFKAMKGLGTDEATILQLLTSRSNAQRQQIKTAYKTLHGKDLVNDLKSELGGKFEDLVVGLMATPVMFDVTTLRNAIKGAGTNEKALIEILASRTPNEIREIIKTYKQEYDHNLEDDVTGDTSGHFKRVLVILLQANRQQ----------------GVQTGNIQSDAQALFNAGEKKYGTDEDEFITILGNRSAEHLRQVFDAYMKLSGFQIEESIQRETSGGLRDVLLAIVKCARSVPAYFAECLYNSMKGAGTDDATLIRIMVSRSEIDLLDIRAEFRKLFATSLHKMIQNDTSGDYRKTLLLLCAGD 315          
BLAST of Annexin vs. Ensembl Cavefish
Match: anxa6 (annexin A6 [Source:NCBI gene;Acc:103026042])

HSP 1 Score: 276.944 bits (707), Expect = 5.167e-88
Identity = 138/331 (41.69%), Postives = 213/331 (64.35%), Query Frame = 1
Query:  157 YKGTIKPFPNFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDLDYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN*D 1149
            ++GT+  FP+F+   D E L  AMKG G+D++AI++ +  R   QR EI+  YK+++GKDLIE LK E++G F++ ++  +    Y+DA  + +A+KGAGT E  L EIL SR+N QI ++   Y   +  D+EQDII +TSG FK++LV  LQ  + +                VV+     ++A  LY AGE++ GTDE++FI +   R+   L+  FDEY+KIA K I DSI SE+SGD + ++ A+     ++P +FA +LYKSMKG GT D TL+R++++RSEID+L+I++ F+  +  +L N ++DDTSG+Y+  L++   G+ D
Sbjct:    9 FRGTVADFPDFDANGDAEALYNAMKGFGSDKEAILDLVTSRSNGQRQEIRSAYKSLYGKDLIEDLKYELTGKFERLIVSLMRPPAYHDAKEIKDAIKGAGTDEKCLIEILASRTNQQIHDLVAAYNDAYGRDIEQDIIGDTSGHFKKMLVVLLQGTRED--------------DGVVHEEVIEEDAQALYAAGEEQWGTDESIFIMLLGNRSVTHLQLVFDEYQKIAEKSIEDSIKSELSGDFERLMLAVVQCIRSRPMFFAKRLYKSMKGLGTADNTLIRIMISRSEIDMLDIRECFRLRYEKSLHNMIQDDTSGEYKRTLLKLCGGDDD 325          

HSP 2 Score: 130.568 bits (327), Expect = 4.572e-33
Identity = 67/155 (43.23%), Postives = 99/155 (63.87%), Query Frame = 1
Query:  154 RYKGTIKPFPNFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDLDYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQ 618
            + +GT+ P  +F+   D + LRKAMKG GTDE  IIE + +R   QR EI+  +K++ G+DL+  LKSE+S N  + ++  +     +DA  + +AM+GAGT E+ L EIL +RSN +I+++   YKK F  +LE  I  +TSG F R+LVS  Q
Sbjct:  351 QLRGTVHPISDFDPGSDAQDLRKAMKGFGTDEDTIIEIVAKRSNEQRQEIRHVFKSILGRDLMADLKSELSKNLCRLIMGLMMTPAEFDAKMMKKAMEGAGTDEHALIEILVTRSNQEIQDMCAAYKKAFKKNLEDAIRSDTSGHFCRILVSLAQ 505          

HSP 3 Score: 115.161 bits (287), Expect = 1.158e-27
Identity = 91/335 (27.16%), Postives = 165/335 (49.25%), Query Frame = 1
Query:  193 VEHDCEVLRKAMK-GIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKK---AVIESLYDLDYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANK-------PELTN--------EQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYK-SMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVE 1137
            +E D + L  A +   GTDE   I  LG R +     +   Y+ +  K + +++KSE+SG+F++   AV++ +     + A  L+++MKG GT +N L  I+ SRS   + +I+  ++  +   L   I  +TSG +KR L+     +        PE             + +VQ RG    ++      +A +L  A  K  GTDE   I+I   R+  Q +     ++ I G+D+   + SE+S +L  ++  +       P  F  K+ K +M+GAGT++  L+ +L+TRS  ++ ++   +++ F   LE+ ++ DTSG +   L+   +
Sbjct:  176 IEEDAQALYAAGEEQWGTDESIFIMLLGNRSVTHLQLVFDEYQKIAEKSIEDSIKSELSGDFERLMLAVVQCIRSRPMFFAKRLYKSMKGLGTADNTLIRIMISRSEIDMLDIRECFRLRYEKSLHNMIQDDTSGEYKRTLLKLCGGDDDIAGEFFPEAAQIAYKMWEISAMTKVQLRGTVHPISDFDPGSDAQDLRKA-MKGFGTDEDTIIEIVAKRSNEQRQEIRHVFKSILGRDLMADLKSELSKNLCRLIMGLMM----TPAEFDAKMMKKAMEGAGTDEHALIEILVTRSNQEIQDMCAAYKKAFKKNLEDAIRSDTSGHFCRILVSLAQ 505          
BLAST of Annexin vs. Ensembl Sea Lamprey
Match: ANXA7 (annexin A7 [Source:HGNC Symbol;Acc:HGNC:545])

HSP 1 Score: 305.064 bits (780), Expect = 2.730e-100
Identity = 156/328 (47.56%), Postives = 224/328 (68.29%), Query Frame = 1
Query:  160 KGTIKPFPNFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDLDYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN 1143
            +GT+KP  NFNV+ DCE+LRKAMKG+GT+E+ +++ +  R  AQR +IK T+KTM+GKDLI  L+SE+SGNF++ ++       YYDA+SL +A++GAGT E VL EIL SR+N +I +I   YK  F  DLE+DI  +TSG FKR+L+S  Q N+ E              S  V++  A  +A +L +AGE K+GTDE+ F  I  +R+  QL+ATF EY K++ +DI ++ID E SG+++  LKAI   A N+P +FA +LY++MKG GT+D+TL+R++ +RSEIDL+N+K  F  ++N TL   ++ DTSGDY+  L   V  N
Sbjct:  147 QGTVKPIGNFNVQDDCEMLRKAMKGLGTNEQVLMDLVVNRSNAQRQKIKLTFKTMYGKDLIRDLRSELSGNFEEIMLALFMPTTYYDAWSLQKAIQGAGTNEKVLVEILCSRTNQEIRDIVSCYKDEFGRDLEKDIKSDTSGHFKRLLISMCQGNRDE--------------SLSVDLALALSDAQKLQSAGEGKLGTDESAFNMILAVRSFPQLQATFQEYIKLSQRDIINTIDREFSGNVKDGLKAIVQCAKNRPVFFAERLYEAMKGGGTDDSTLIRIVTSRSEIDLVNVKHAFLEKYNKTLYKMIEGDTSGDYKRMLQAIVGQN 460          

HSP 2 Score: 75.485 bits (184), Expect = 3.527e-15
Identity = 43/148 (29.05%), Postives = 81/148 (54.73%), Query Frame = 1
Query:  706 QEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN*D 1149
            Q+  E+     K +GT+E + + +   R+  Q +     ++ + GKD+   + SE+SG+ + ++ A+        +Y A  L K+++GAGTN+  LV +L +R+  ++ +I   ++ EF   LE  +K DTSG ++  L+   +GN D
Sbjct:  159 QDDCEMLRKAMKGLGTNEQVLMDLVVNRSNAQRQKIKLTFKTMYGKDLIRDLRSELSGNFEEIMLALFMPTT---YYDAWSLQKAIQGAGTNEKVLVEILCSRTNQEIRDIVSCYKDEFGRDLEKDIKSDTSGHFKRLLISMCQGNRD 303          
BLAST of Annexin vs. Ensembl Sea Lamprey
Match: ANXA7 (annexin A7 [Source:HGNC Symbol;Acc:HGNC:545])

HSP 1 Score: 293.508 bits (750), Expect = 7.900e-95
Identity = 149/325 (45.85%), Postives = 221/325 (68.00%), Query Frame = 1
Query:  160 KGTIKPFPNFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDLDYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFV 1134
            +GTI    NFN + D EVLR+AMKG+GTDE+A+I+ +  R   QR +IK  +KTM+GKDLI  L+SE+SGNF++ ++       YYDA+SL +A+KGAGT E VL EI+ +R+N +I+ I  +Y++ FN  LE+DI  +TSG FKR+L+S  Q N+ E              S  V++++A+ +A  LY AGE K+GTDE+ F  I   R+  QL+ATF+EY ++A +DI ++ID E SGD++  ++AI     ++P YFA +L+ SMKG GT+D+ L+RV+++RSEIDL +IK+ F +++  TL   ++ DTSGDY+  L+  V
Sbjct:  231 RGTIHTASNFNAQDDAEVLRRAMKGLGTDERALIDIIVNRSNDQRQKIKLAFKTMYGKDLIRDLRSELSGNFEEIILALFMPTTYYDAWSLMKAIKGAGTDEKVLIEIMCTRTNQEIKEIVRVYREEFNRTLEKDIRSDTSGHFKRLLISMCQGNRDE--------------SQTVDMSKAQSDAQRLYTAGEGKLGTDESTFNMILACRSFPQLQATFNEYTRMAQRDIVNTIDREFSGDIRDGMRAIVQCVRSRPAYFAERLFHSMKGLGTDDSGLIRVIVSRSEIDLQDIKQAFLQQYQKTLYTMIQGDTSGDYKRILVAIV 541          

HSP 2 Score: 80.1073 bits (196), Expect = 1.426e-16
Identity = 49/159 (30.82%), Postives = 85/159 (53.46%), Query Frame = 1
Query:  673 ISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN*D 1149
            I    N N   Q+  E+     K +GTDE   I I   R+  Q +     ++ + GKD+   + SE+SG+ + ++ A+        +Y A  L K++KGAGT++  L+ ++ TR+  ++  I + ++ EFN TLE  ++ DTSG ++  L+   +GN D
Sbjct:  234 IHTASNFNA--QDDAEVLRRAMKGLGTDERALIDIIVNRSNDQRQKIKLAFKTMYGKDLIRDLRSELSGNFEEIILALFMPTT---YYDAWSLMKAIKGAGTDEKVLIEIMCTRTNQEIKEIVRVYREEFNRTLEKDIRSDTSGHFKRLLISMCQGNRD 387          
BLAST of Annexin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001517.1 (pep scaffold:Pmarinus_7.0:GL476341:319620:335761:1 gene:ENSPMAG00000001365.1 transcript:ENSPMAT00000001517.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 271.937 bits (694), Expect = 2.719e-89
Identity = 147/324 (45.37%), Postives = 205/324 (63.27%), Query Frame = 1
Query:  166 TIKPFPNFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDLD-YYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFV 1134
            TI P+ +F+   D + LRKA KG+GTDE  IIE L  R   QR +IK+ YK  +G DL+E LK E+ G+F+K V+ +L DL   YDA  L +AMKGAGT E+VL EIL +R+N QI+ ++ +Y + F+ DLE D+  ETSG  +++L++ +Q N+ E T+              VN++ A  +A EL+ AG+   GTDE  F  +   RN  QLRATF  Y+   G+DI D + SE SG LQ    AI   A++   YFA KLYKSMKG GT+D TL+R +++RS+IDL  IK+ FQ+++  TL +FV  D SGDY+  L+  +
Sbjct:    7 TIHPYADFDAAKDAKDLRKACKGLGTDEDKIIEILANRTAKQRHQIKEEYKRSYGDDLVEVLKGELKGDFEKVVL-ALMDLPAVYDAKELRKAMKGAGTDEDVLVEILCTRTNKQIQKMRFVYNELFDRDLESDLKSETSGAVEKLLIALVQGNRDETTD--------------VNMSLANSDAKELHEAGKGHWGTDELAFNSVLATRNMMQLRATFKAYKTNYGEDIEDVVKSETSGMLQDAYLAIVHCAMDAQEYFAKKLYKSMKGTGTDDDTLIRCIVSRSQIDLGTIKETFQQKYEKTLASFVAGDCSGDYKKILLAVI 315          

HSP 2 Score: 72.7886 bits (177), Expect = 1.441e-14
Identity = 50/151 (33.11%), Postives = 83/151 (54.97%), Query Frame = 1
Query:  700 ARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKP-FYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN*D 1149
            A ++A +L  A  K +GTDE   I+I   R   Q     +EY++  G D+ + +  E+ GD + V+ A+    ++ P  Y A +L K+MKGAGT++  LV +L TR+   +  ++  +   F+  LE+ +K +TSG     L+  V+GN D
Sbjct:   16 AAKDAKDLRKAC-KGLGTDEDKIIEILANRTAKQRHQIKEEYKRSYGDDLVEVLKGELKGDFEKVVLAL----MDLPAVYDAKELRKAMKGAGTDEDVLVEILCTRTNKQIQKMRFVYNELFDRDLESDLKSETSGAVEKLLIALVQGNRD 161          
BLAST of Annexin vs. Ensembl Sea Lamprey
Match: ANXA11 (annexin A11 [Source:HGNC Symbol;Acc:HGNC:535])

HSP 1 Score: 266.544 bits (680), Expect = 6.269e-85
Identity = 146/338 (43.20%), Postives = 205/338 (60.65%), Query Frame = 1
Query:  133 QIGVKGERY-KGTIKPFPNFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDLDYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN 1143
            Q G  G++  +GT+K    FN   D E LRKAMKG GTDEKAII+ L  R   QR EI  ++KT +GKDL++ LKSE+SGNF+  V+  L     YD   +  A+KGAGT E  L EIL SRSN +I  I   YK      LEQDI+ +TS  FKR+LV+  Q  + E              S  V++ + +++A +L  AGE +IGTDE+ F  I C R++  L   F+EY +I+  DI  SI  EMSG L+  + A+     N   +FA +LYKSMKG GT D+TL+R++++R E+DL +I++EF++ +  +L +F+  DTSGDY+  L+    G+
Sbjct:  166 QCGPSGQKKGRGTVKEQSGFNALKDAETLRKAMKGFGTDEKAIIDVLTARSNKQRQEIALSFKTAYGKDLVKELKSELSGNFELVVVALLETPTQYDVSQIQAAIKGAGTDEECLIEILASRSNKEIHEINKHYKSVTKRSLEQDIMSDTSANFKRLLVALCQGGRDE--------------STTVDMARVQKDAQDLLAAGENRIGTDESRFNSILCGRSQAHLLRVFEEYGRISKHDIEKSIKREMSGSLEDGMVAVVKCLRNTQGFFAERLYKSMKGLGTKDSTLIRIMVSRCEVDLFDIRREFKQLYGKSLHSFIAGDTSGDYKKILLSLCGGD 489          

HSP 2 Score: 62.7734 bits (151), Expect = 6.155e-11
Identity = 37/137 (27.01%), Postives = 70/137 (51.09%), Query Frame = 1
Query:  739 KKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN*D 1149
            K  GTDE   I +   R+  Q +     ++   GKD+   + SE+SG+ + V+ A+         Y  +++  ++KGAGT++  L+ +L +RS  ++  I K ++     +LE  +  DTS +++  L+   +G  D
Sbjct:  199 KGFGTDEKAIIDVLTARSNKQRQEIALSFKTAYGKDLVKELKSELSGNFELVVVALLETPTQ---YDVSQIQAAIKGAGTDEECLIEILASRSNKEIHEINKHYKSVTKRSLEQDIMSDTSANFKRLLVALCQGGRD 332          
BLAST of Annexin vs. Ensembl Sea Lamprey
Match: anxa2a (annexin A2a [Source:ZFIN;Acc:ZDB-GENE-030131-4282])

HSP 1 Score: 188.348 bits (477), Expect = 1.429e-56
Identity = 116/323 (35.91%), Postives = 183/323 (56.66%), Query Frame = 1
Query:  157 YKGTIKPFPNFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDLDYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVN-KPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYL 1122
            Y  T+KP+PNFN  +D   L+KA+   G DEK II  L  R   QR EI K+YK    KDL   LK  +SG+ +  ++  L     YDA  + + ++G GT E  L E+L +R N ++ ++ + YK  F  D+ QDI K+TSG F++++++  +  + E + +    V E              +A EL+ AG K+ GTD   FI I   R+   L+  F+ Y+      I DS + E+ GDL++   ++A +A+N  P +FA KL+ SMKG GT D  L+ ++++R E+DLL+I+ EF++++  +L + +  DT+GDY   L
Sbjct:   24 YGPTVKPYPNFNANNDAAALQKAITTKGVDEKTIISILTNRTNTQRQEIIKSYKNATSKDLATDLKGALSGHLETVILGLLMTPAIYDAHIIRQTLQGLGTDEECLIEMLVTRDNLRLRSMAVAYKSEFKSDMMQDIAKDTSGDFQKLVLALAKGARIEDSTKDHDLVDE--------------DARELFEAGVKRKGTDVGKFITIMSQRSFSHLKKVFEAYKSYYPAGIVDSFEKEVGGDLRNAFVSLA-KAINYTPGFFAEKLHDSMKGLGTKDHMLIHIMVSRCELDLLHIRTEFKKKYKKSLYSAIASDTNGDYEVAL 331          

HSP 2 Score: 58.151 bits (139), Expect = 1.139e-9
Identity = 32/131 (24.43%), Postives = 64/131 (48.85%), Query Frame = 1
Query:  748 GTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEG 1140
            G DE   I I   R   Q +     Y+    KD+   +   +SG L++V+  +    +    Y A  + ++++G GT++  L+ +L+TR  + L ++   ++ EF   +   +  DTSGD++  ++   +G
Sbjct:   51 GVDEKTIISILTNRTNTQRQEIIKSYKNATSKDLATDLKGALSGHLETVILGLL---MTPAIYDAHIIRQTLQGLGTDEECLIEMLVTRDNLRLRSMAVAYKSEFKSDMMQDIAKDTSGDFQKLVLALAKG 178          
BLAST of Annexin vs. Ensembl Nematostella
Match: EDO28444 (Annexin [Source:UniProtKB/TrEMBL;Acc:A7T6G0])

HSP 1 Score: 270.011 bits (689), Expect = 1.111e-88
Identity = 142/306 (46.41%), Postives = 201/306 (65.69%), Query Frame = 1
Query:  226 MKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDLDYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN 1143
            M+G+GT+E  +I  L  R  AQR+EI+K YKTM+GKDL+  LKSE+SGN ++ ++  +     YDA  L   M+GAGT E  L +IL +RSN +IE IK  YK+++  DLE+D + ETSG FKR+LVS  Q N              R  +  V++ +A +EA +LY AGEKK GTDE+ F  +   R+  QL+ATF+EY KI+ +DI +SID EMSGDL++  + I   A N   YFA +L+KSMKGAGT+D+ L+RV+++RSE+DL+ IK  F ++++ T+   ++ D SGDY+  LM  V  N
Sbjct:    1 MRGMGTNEAELIGILANRSNAQRVEIRKRYKTMYGKDLMNDLKSELSGNLEECLLAMMEPSVLYDAKCLRRGMRGAGTDEETLIDILCTRSNQEIEAIKREYKEYYKRDLEKDCVSETSGHFKRLLVSMCQGN--------------RDTNMTVDMAKATKEAQDLYKAGEKKWGTDESRFNVVLASRSFPQLQATFNEYIKISQRDIMNSIDREMSGDLKAGFRCIVQCARNPAEYFADRLWKSMKGAGTDDSLLIRVVVSRSEVDLVEIKASFLQKYHKTVYKMIEGDCSGDYKKLLMALVGKN 292          

HSP 2 Score: 78.9518 bits (193), Expect = 1.686e-16
Identity = 46/138 (33.33%), Postives = 78/138 (56.52%), Query Frame = 1
Query:  739 KKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN*DS 1152
            + +GT+EA  I I   R+  Q       Y+ + GKD+ + + SE+SG+L+  L A+   +V    Y A  L + M+GAGT++ TL+ +L TRS  ++  IK+E++  +   LE     +TSG ++  L+   +GN D+
Sbjct:    2 RGMGTNEAELIGILANRSNAQRVEIRKRYKTMYGKDLMNDLKSELSGNLEECLLAMMEPSV---LYDAKCLRRGMRGAGTDEETLIDILCTRSNQEIEAIKREYKEYYKRDLEKDCVSETSGHFKRLLVSMCQGNRDT 136          

HSP 3 Score: 67.0106 bits (162), Expect = 1.559e-12
Identity = 66/254 (25.98%), Postives = 112/254 (44.09%), Query Frame = 1
Query:  190 NVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLY-DLDYYDAFSLHEAMKGA-----------GTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFK---RVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAI 906
            +V +D + LR+ M+G GTDE+ +I+ L  R   +   IK+ YK  + +DL +   SE SG+FK+ ++     + D      + +A K A           GT E+    +L SRS  Q++     Y K    D+   I +E SG  K   R +V C +                         N A   A  L+ +  K  GTD+++ I++   R++  L      + +   K ++  I+ + SGD + +L A+
Sbjct:   61 SVLYDAKCLRRGMRGAGTDEETLIDILCTRSNQEIEAIKREYKEYYKRDLEKDCVSETSGHFKRLLVSMCQGNRDTNMTVDMAKATKEAQDLYKAGEKKWGTDESRFNVVLASRSFPQLQATFNEYIKISQRDIMNSIDREMSGDLKAGFRCIVQCAR-------------------------NPAEYFADRLWKS-MKGAGTDDSLLIRVVVSRSEVDLVEIKASFLQKYHKTVYKMIEGDCSGDYKKLLMAL 288          
BLAST of Annexin vs. Ensembl Nematostella
Match: EDO32043 (Annexin [Source:UniProtKB/TrEMBL;Acc:A7SW86])

HSP 1 Score: 270.011 bits (689), Expect = 3.987e-88
Identity = 144/325 (44.31%), Postives = 206/325 (63.38%), Query Frame = 1
Query:  160 KGTIKPFPNFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDLDYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFV 1134
            + +++ + +F+   D + LRKAMKG+G D KA++  L  R  +QR  I   YKTMFG+DLI+ LKSE+ G F+  VI  +     YDA  L +A+KG GT E VL E+LT+R+N +I  I+  Y   F+ DLE+DI  +TSG FK+ L+S   AN+ E              +A V+ ++A+Q+A  LY AGE + GTDE+ F  I   R+  QLRATF+EY KI   DI +SI  EMSGDL+  +  I     N P +FA KLYKSMKG GT+D TL+R+++TRSE+D+L+I+ EF + +  TL  ++ DDT G+Y+  L++ +
Sbjct:   16 RPSVREYTSFDGRKDADTLRKAMKGLGCDNKALMYLLCSRTNSQRQRISLEYKTMFGRDLIKDLKSEVGGYFEDTVIALMTPPAEYDATLLRKAIKGLGTDEAVLIEVLTTRTNDEIIAIRNAYNTLFSRDLEKDIAGDTSGKFKKFLISLCNANRIE--------------TAPVDYSKAQQDAQALYKAGEGRWGTDESKFNSILASRSFDQLRATFNEYSKICKYDIEESIKREMSGDLRDGMVTIVRVVKNAPAFFAEKLYKSMKGLGTDDKTLIRIVVTRSEVDMLDIRDEFHKMYGTTLARYISDDTKGNYKKILLQLI 326          

HSP 2 Score: 90.5077 bits (223), Expect = 2.463e-20
Identity = 76/273 (27.84%), Postives = 126/273 (46.15%), Query Frame = 1
Query:  148 GERYKGTIKPFPNFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIE-------SLYDLDYY----DAFSLHEAMKG-AGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKP 930
            G  ++ T+        E+D  +LRKA+KG+GTDE  +IE L  R   + + I+  Y T+F +DL + +  + SG FKK +I            +DY     DA +L++A +G  GT E+    IL SRS  Q+      Y K   +D+E+ I +E SG  +  +V+ ++  K                      N     A +LY +  K +GTD+   I+I   R++  +    DE+ K+ G  +   I  +  G+ + +L     Q + +P
Sbjct:   84 GGYFEDTVIALMTPPAEYDATLLRKAIKGLGTDEAVLIEVLTTRTNDEIIAIRNAYNTLFSRDLEKDIAGDTSGKFKKFLISLCNANRIETAPVDYSKAQQDAQALYKAGEGRWGTDESKFNSILASRSFDQLRATFNEYSKICKYDIEESIKREMSGDLRDGMVTIVRVVK----------------------NAPAFFAEKLYKS-MKGLGTDDKTLIRIVVTRSEVDMLDIRDEFHKMYGTTLARYISDDTKGNYKKIL----LQLIGEP 329          

HSP 3 Score: 67.0106 bits (162), Expect = 2.190e-12
Identity = 47/175 (26.86%), Postives = 84/175 (48.00%), Query Frame = 1
Query:  619 ANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN 1143
            ++ P L+++  R  Q R           R++A  L  A  K +G D    + + C R   Q +    EY+ + G+D+   + SE+ G  +  + A+         Y AT L K++KG GT++  L+ VL TR+  +++ I+  +   F+  LE  +  DTSG ++ +L+     N
Sbjct:    2 SSAPHLSSKPTR--QGRPSVREYTSFDGRKDADTLRKA-MKGLGCDNKALMYLLCSRTNSQRQRISLEYKTMFGRDLIKDLKSEVGGYFEDTVIALMTPPAE---YDATLLRKAIKGLGTDEAVLIEVLTTRTNDEIIAIRNAYNTLFSRDLEKDIAGDTSGKFKKFLISLCNAN 170          
BLAST of Annexin vs. Ensembl Nematostella
Match: EDO44051 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RWX3])

HSP 1 Score: 230.335 bits (586), Expect = 8.211e-73
Identity = 129/328 (39.33%), Postives = 191/328 (58.23%), Query Frame = 1
Query:  157 YKGTIKPFPNFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDLDYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISA--VVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFV 1134
            Y GT+    NF+     E L+KAMKG G DE+AIIE L    L QRL I +++K  + KDL+  LKSE+SG F+ A++  L   +  DA +LH AM+G GT ++VL EIL SRS  ++++IK  Y      DL   +  ETSG F+ +LV+ L A +               +SA  +VN +QA ++A  LY AGEKK GTDE++F KI   R+  QLRA +  Y+ +A  DI ++ID E++GD    +KAI       P YFA  L  ++ G  T+ + + R++++RSE+DL +IK  ++  +  TL   VK+   GD+   L++ +
Sbjct:    2 YHGTVVAAENFDAGDCAEKLKKAMKGFGDDEEAIIEVLQSCNLEQRLAIAQSFKQQYDKDLVNELKSELSGKFEDAIVALLLPPEQLDANALHGAMQGLGTNDSVLIEILCSRSAEELQSIKKAYNTAHGKDLVAAVKSETSGDFQALLVALLDAKR---------------VSADEIVNEDQAYEDAKNLYEAGEKKWGTDESVFTKILTCRSDLQLRALYQAYQHVAKCDILETIDDELTGDYHDAVKAIVRCTRRPPLYFAESLNSALNGLRTDSSLVTRIIISRSEVDLADIKAVYKDTYGKTLATEVKELLKGDHETLLLKIL 314          

HSP 2 Score: 65.0846 bits (157), Expect = 7.993e-12
Identity = 45/153 (29.41%), Postives = 76/153 (49.67%), Query Frame = 1
Query:  712 ATELYNAGE---------KKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYF-ATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEG 1140
            A E ++AG+         K  G DE   I++    N  Q  A    +++   KD+ + + SE+SG  +  + A+       P    A  L+ +M+G GTND+ L+ +L +RS  +L +IKK +       L   VK +TSGD++A L+  ++ 
Sbjct:    8 AAENFDAGDCAEKLKKAMKGFGDDEEAIIEVLQSCNLEQRLAIAQSFKQQYDKDLVNELKSELSGKFEDAIVALLL----PPEQLDANALHGAMQGLGTNDSVLIEILCSRSAEELQSIKKAYNTAHGKDLVAAVKSETSGDFQALLVALLDA 156          

HSP 3 Score: 48.521 bits (114), Expect = 2.612e-6
Identity = 35/133 (26.32%), Postives = 66/133 (49.62%), Query Frame = 1
Query:  229 KGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFK---KAVIESLYDLDYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQ 618
            K  GTDE    + L  R   Q   + + Y+ +   D++E +  E++G++    KA++        Y A SL+ A+ G  T  +++T I+ SRS   + +IK +YK  +   L  ++ +   G  + +L+  L+
Sbjct:  183 KKWGTDESVFTKILTCRSDLQLRALYQAYQHVAKCDILETIDDELTGDYHDAVKAIVRCTRRPPLYFAESLNSALNGLRTDSSLVTRIIISRSEVDLADIKAVYKDTYGKTLATEVKELLKGDHETLLLKILR 315          
BLAST of Annexin vs. Ensembl Nematostella
Match: EDO29757 (Annexin [Source:UniProtKB/TrEMBL;Acc:A7T2R2])

HSP 1 Score: 139.428 bits (350), Expect = 1.800e-39
Identity = 79/200 (39.50%), Postives = 118/200 (59.00%), Query Frame = 1
Query:  538 FFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRA-TFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFV 1134
             F+ DLE+DI  +TSG FK+ L+S   AN+ E              +A V+  +A+Q+A  LY AGE + GTDE+  +      + +  RA       +I   DI +SI  EMSGDL+  +  I     N P +FA KLYKSMKG GT+D TL+R+++TRSE+D+L+I+ EF + +  TL  ++ DDT G+Y+  L++ +
Sbjct:    1 MFSRDLEKDIAGDTSGKFKKFLISLCNANRIE--------------TAPVDYLKAQQDAQALYKAGEGRWGTDESNHV-TETQESSFGERARMLTPSVRICKYDIEESIKREMSGDLRDGMVTIVRVVKNAPAFFAEKLYKSMKGLGTDDKTLIRIVVTRSEVDMLDIRDEFHKMYGTTLAKYISDDTKGNYKKILLQLI 185          
BLAST of Annexin vs. Ensembl Nematostella
Match: EDO44049 (Annexin [Source:UniProtKB/TrEMBL;Acc:A7RWX1])

HSP 1 Score: 111.309 bits (277), Expect = 2.806e-29
Identity = 70/176 (39.77%), Postives = 100/176 (56.82%), Query Frame = 1
Query:  442 MKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYF-ATKLYKSMK 966
            ++G GT E+ L  IL +RSN +I +IK +YKK ++  LE D+  +TSG F+ +LV  LQ  + E              S  +N + A ++A  L  AG KK GTDE  FI+IF  R+  QL+A F EY K A  DI D+I SEM GDL+  L  +  +A+  P    A KL+ +++
Sbjct:    2 LQGFGTDEDALISILCTRSNKEINDIKEVYKKNYDTTLEDDVKGDTSGDFEDLLVKLLQGKRDE--------------SDEINEDLAHKDAEALIEAGIKKWGTDEDCFIEIFTTRSYPQLQAMFPEYSKWAKCDIEDTISSEMDGDLKDAL-LVLVKAIQSPTQMTADKLHSALQ 162          

HSP 2 Score: 62.3882 bits (150), Expect = 1.025e-11
Identity = 46/144 (31.94%), Postives = 74/144 (51.39%), Query Frame = 1
Query:  226 MKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLY-----------DLDYYDAFSLHEA-MKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQA 621
            ++G GTDE A+I  L  R   +  +IK+ YK  +   L + +K + SG+F+  +++ L            DL + DA +L EA +K  GT E+   EI T+RS  Q++ +   Y K+   D+E  I  E  G  K  L+  ++A
Sbjct:    2 LQGFGTDEDALISILCTRSNKEINDIKEVYKKNYDTTLEDDVKGDTSGDFEDLLVKLLQGKRDESDEINEDLAHKDAEALIEAGIKKWGTDEDCFIEIFTTRSYPQLQAMFPEYSKWAKCDIEDTISSEMDGDLKDALLVLVKA 145          

HSP 3 Score: 51.2174 bits (121), Expect = 7.611e-8
Identity = 23/63 (36.51%), Postives = 44/63 (69.84%), Query Frame = 1
Query:  961 MKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN*D 1149
            ++G GT++  L+ +L TRS  ++ +IK+ +++ ++ TLE+ VK DTSGD+   L++ ++G  D
Sbjct:    2 LQGFGTDEDALISILCTRSNKEINDIKEVYKKNYDTTLEDDVKGDTSGDFEDLLVKLLQGKRD 64          
BLAST of Annexin vs. Ensembl Medaka
Match: anxa11a (annexin A5 [Source:NCBI gene;Acc:101174691])

HSP 1 Score: 304.294 bits (778), Expect = 1.041e-98
Identity = 157/327 (48.01%), Postives = 215/327 (65.75%), Query Frame = 1
Query:  163 GTIKPFPNFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDLDYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN 1143
            GTI  FP  +   D EVLRKAMKG GTDE+AII  LG R   QR+ + + YKT +GKDL++ L SE+SG+F+K V+ +L     +DA  LH A+KGAGT E  L EIL+SRSN +I+ I  +YK+ +   LE  I  +TSG F+R+L+S  Q N+ E      RE         V+ + A Q+A  LY AGE K+GTDE+ F  I C R+K  LRA F EY+++ G+DI  SI  EMSGDL+S + A+     N P YFA +LYK+MKGAGT DTTL+R++++RSE+DLL+I+KE+ + +  +L   +  DTSGDY+  L++F  G+
Sbjct:  194 GTITDFPGADPLKDVEVLRKAMKGFGTDEQAIINLLGSRSNKQRVPLLRAYKTSYGKDLVKDLHSELSGDFRKLVLATLKTPAEFDASELHSAIKGAGTDEACLIEILSSRSNAEIKEINRIYKQEYKKSLEDSISGDTSGHFRRLLISLAQGNRDE------RET--------VDASLAAQDAQALYAAGENKLGTDESKFNAILCARSKPHLRAVFHEYQRMCGRDIEKSISREMSGDLESGMLAVVKCIKNTPAYFAERLYKAMKGAGTKDTTLIRIMVSRSEVDLLDIRKEYVKNYGKSLYTAISGDTSGDYKKLLLKFCGGS 506          

HSP 2 Score: 81.2629 bits (199), Expect = 3.223e-16
Identity = 45/140 (32.14%), Postives = 78/140 (55.71%), Query Frame = 1
Query:  739 KKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYF-ATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN*DSR 1155
            K  GTDE   I +   R+  Q       Y+   GKD+   + SE+SGD + ++ A     +  P  F A++L+ ++KGAGT++  L+ +L +RS  ++  I + +++E+  +LE+ +  DTSG +R  L+   +GN D R
Sbjct:  216 KGFGTDEQAIINLLGSRSNKQRVPLLRAYKTSYGKDLVKDLHSELSGDFRKLVLAT----LKTPAEFDASELHSAIKGAGTDEACLIEILSSRSNAEIKEINRIYKQEYKKSLEDSISGDTSGHFRRLLISLAQGNRDER 351          
BLAST of Annexin vs. Ensembl Medaka
Match: anxa4 (annexin A4 [Source:NCBI gene;Acc:100049454])

HSP 1 Score: 283.108 bits (723), Expect = 6.836e-93
Identity = 149/327 (45.57%), Postives = 204/327 (62.39%), Query Frame = 1
Query:  160 KGTIKPFPNFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDLDYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEG 1140
            +GT+     FN + D + LR+AMKG GTDE AII+ L  R +AQR  IK  YK   GKDL E L SE+SG+F+  V+  L     YDA+ L  AMKGAGT E  L +IL SRSN ++  I  +YKK +   LE  +  +TSG F+RVLVS L A + E              S  V+  QA ++A +++ AGE + GTDE  F+ + C+RN+  L   FDEY+KI+ +DI DSI  EMSG L+ V  AI     +KP +FA +LYKSMKG GT D+ L+R++++R+EID+L+IK+ F + +  +L +F+K DTSGDYR  L+    G
Sbjct:    7 RGTVTEASGFNPDDDAQKLREAMKGAGTDEAAIIKVLAHRTIAQRQRIKLAYKQSVGKDLAEDLSSELSGHFQSVVLGLLMPAPVYDAYELKAAMKGAGTEEACLIDILASRSNSEMNAINEVYKKEYGKTLEDAVCGDTSGMFQRVLVSLLTAGRDE--------------SDKVDEAQAVKDAKDIFEAGEARWGTDEVKFLTVLCVRNRNHLLRVFDEYKKISKRDIEDSIKREMSGSLEDVFLAIVKCLRSKPAFFAERLYKSMKGLGTTDSVLIRIMVSRAEIDMLDIKEHFLKTYGKSLHSFIKGDTSGDYRKILLELCGG 319          

HSP 2 Score: 81.6481 bits (200), Expect = 6.597e-17
Identity = 48/137 (35.04%), Postives = 76/137 (55.47%), Query Frame = 1
Query:  739 KKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN*D 1149
            K  GTDEA  IK+   R   Q +     Y++  GKD+ + + SE+SG  QSV+  +   A   P Y A +L  +MKGAGT +  L+ +L +RS  ++  I + +++E+  TLE+ V  DTSG ++  L+  +    D
Sbjct:   30 KGAGTDEAAIIKVLAHRTIAQRQRIKLAYKQSVGKDLAEDLSSELSGHFQSVVLGLLMPA---PVYDAYELKAAMKGAGTEEACLIDILASRSNSEMNAINEVYKKEYGKTLEDAVCGDTSGMFQRVLVSLLTAGRD 163          
BLAST of Annexin vs. Ensembl Medaka
Match: anxa11 (annexin max4 [Source:NCBI gene;Acc:100049456])

HSP 1 Score: 286.96 bits (733), Expect = 2.049e-92
Identity = 154/326 (47.24%), Postives = 209/326 (64.11%), Query Frame = 1
Query:  157 YKGTIKPFPNFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDLDYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFV 1134
            Y+G+IK FP  +   D EVLRKAMKG GTDEKAIIE LG R   QR+ +   YKT +GKDL   LKSE++GNF+  V+  L     +DA  L EA+KGAGT E  L EIL+SRSN +I  I  +YK  +   LE  I  +TSG F+R+LVS  Q N+ E      RE         V+I+ A+Q+A +LY AGE K+GTDE+ F  I C R+K  LRA F EY+++ GK+I  SI  E SG+L+  + A+     N P YFA +L K+MKGAGT D TL+RV+++RSE+D+L+I++E+ + +  +L   +  DTSGDY+  L++  
Sbjct:  153 YRGSIKDFPGADPLRDVEVLRKAMKGFGTDEKAIIELLGNRTNKQRVPLVAAYKTTYGKDLFRDLKSELTGNFEDLVVAMLKTPTQFDASELREAIKGAGTDEACLIEILSSRSNAEIIEINKVYKAEYGKTLEDSISSDTSGHFRRLLVSLCQGNRDE------RE--------TVDISLAKQDAQKLYAAGENKVGTDESQFNAILCARSKPHLRAVFHEYQQMCGKEIEKSICRETSGNLEDGMVAVVKCIKNTPAYFAERLRKAMKGAGTKDRTLIRVMVSRSEVDMLDIRQEYLKAYGKSLYTDISGDTSGDYKNLLLKLC 464          

HSP 2 Score: 83.5741 bits (205), Expect = 4.001e-17
Identity = 46/140 (32.86%), Postives = 80/140 (57.14%), Query Frame = 1
Query:  739 KKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYF-ATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN*DSR 1155
            K  GTDE   I++   R   Q       Y+   GKD+F  + SE++G+ + ++ A+    +  P  F A++L +++KGAGT++  L+ +L +RS  +++ I K ++ E+  TLE+ +  DTSG +R  L+   +GN D R
Sbjct:  177 KGFGTDEKAIIELLGNRTNKQRVPLVAAYKTTYGKDLFRDLKSELTGNFEDLVVAM----LKTPTQFDASELREAIKGAGTDEACLIEILSSRSNAEIIEINKVYKAEYGKTLEDSISSDTSGHFRRLLVSLCQGNRDER 312          
BLAST of Annexin vs. Ensembl Medaka
Match: anxa11 (annexin max4 [Source:NCBI gene;Acc:100049456])

HSP 1 Score: 286.96 bits (733), Expect = 4.800e-92
Identity = 154/326 (47.24%), Postives = 209/326 (64.11%), Query Frame = 1
Query:  157 YKGTIKPFPNFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDLDYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFV 1134
            Y+G+IK FP  +   D EVLRKAMKG GTDEKAIIE LG R   QR+ +   YKT +GKDL   LKSE++GNF+  V+  L     +DA  L EA+KGAGT E  L EIL+SRSN +I  I  +YK  +   LE  I  +TSG F+R+LVS  Q N+ E      RE         V+I+ A+Q+A +LY AGE K+GTDE+ F  I C R+K  LRA F EY+++ GK+I  SI  E SG+L+  + A+     N P YFA +L K+MKGAGT D TL+RV+++RSE+D+L+I++E+ + +  +L   +  DTSGDY+  L++  
Sbjct:  193 YRGSIKDFPGADPLRDVEVLRKAMKGFGTDEKAIIELLGNRTNKQRVPLVAAYKTTYGKDLFRDLKSELTGNFEDLVVAMLKTPTQFDASELREAIKGAGTDEACLIEILSSRSNAEIIEINKVYKAEYGKTLEDSISSDTSGHFRRLLVSLCQGNRDE------RE--------TVDISLAKQDAQKLYAAGENKVGTDESQFNAILCARSKPHLRAVFHEYQQMCGKEIEKSICRETSGNLEDGMVAVVKCIKNTPAYFAERLRKAMKGAGTKDRTLIRVMVSRSEVDMLDIRQEYLKAYGKSLYTDISGDTSGDYKNLLLKLC 504          

HSP 2 Score: 83.5741 bits (205), Expect = 4.651e-17
Identity = 46/140 (32.86%), Postives = 80/140 (57.14%), Query Frame = 1
Query:  739 KKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYF-ATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN*DSR 1155
            K  GTDE   I++   R   Q       Y+   GKD+F  + SE++G+ + ++ A+    +  P  F A++L +++KGAGT++  L+ +L +RS  +++ I K ++ E+  TLE+ +  DTSG +R  L+   +GN D R
Sbjct:  217 KGFGTDEKAIIELLGNRTNKQRVPLVAAYKTTYGKDLFRDLKSELTGNFEDLVVAM----LKTPTQFDASELREAIKGAGTDEACLIEILSSRSNAEIIEINKVYKAEYGKTLEDSISSDTSGHFRRLLVSLCQGNRDER 352          
BLAST of Annexin vs. Ensembl Medaka
Match: anxa10 (annexin A10 [Source:NCBI gene;Acc:100049533])

HSP 1 Score: 280.026 bits (715), Expect = 8.822e-92
Identity = 152/328 (46.34%), Postives = 205/328 (62.50%), Query Frame = 1
Query:  160 KGTIKPFPNFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDLDYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN 1143
            KGT+K   NF    D EVL KAMKGIGTDE AI++ +  R  AQR EIK TYKT+FGKDLI+ LK E+ G F+  ++  +     YD  SL  A+KGAGT E VL EIL SR+  Q+++I   Y+K ++ DLE+DI  +TSG FKR+LV  LQAN+          VQE  I           +A  L+ AGE+K GTDE  F+ +   R+   LR  FD Y K++G +I +SI  E SG L+ +L A+   A + P YFA  LY +MKGAGT+D TL+RV++TR E+D+L+I+ EF++ F  +L + +K DT GDYR  L+    G+
Sbjct:    4 KGTVKAAANFKASADAEVLHKAMKGIGTDEDAILQLVCARSNAQRQEIKATYKTLFGKDLIDDLKGELGGKFETLIVALMTPPTAYDVVSLRNAIKGAGTDEKVLVEILASRTPQQVKDIIAAYRKEYDADLEEDICGDTSGHFKRLLVILLQANRQT-------GVQEGDI---------ENDAQVLFKAGEQKFGTDEQTFVTLLGNRSAQHLRKVFDAYMKLSGYEIEESIKRETSGSLKDLLLAVVKCARSVPAYFAETLYNAMKGAGTDDDTLIRVMVTRGEVDMLDIRAEFRKLFARSLFSMIKGDTGGDYRKALLLLCGGD 315          

HSP 2 Score: 75.8702 bits (185), Expect = 6.776e-15
Identity = 70/267 (26.22%), Postives = 116/267 (43.45%), Query Frame = 1
Query:  130 DQIGVKGERYKGTIKPFPNFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLY----------DLDYYDAFSLHEAMKGA-GTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVL 897
            D  G  G +++  I         +D   LR A+KG GTDEK ++E L  R   Q  +I   Y+  +  DL E +  + SG+FK+ ++  L           D++  DA  L +A +   GT E     +L +RS   +  +   Y K   +++E+ I +ETSG  K +L++ ++                R + A          A  LYNA  K  GTD+   I++   R +  +     E+ K+  + +F  I  +  GD +  L
Sbjct:   66 DLKGELGGKFETLIVALMTPPTAYDVVSLRNAIKGAGTDEKVLVEILASRTPQQVKDIIAAYRKEYDADLEEDICGDTSGHFKRLLVILLQANRQTGVQEGDIE-NDAQVLFKAGEQKFGTDEQTFVTLLGNRSAQHLRKVFDAYMKLSGYEIEESIKRETSGSLKDLLLAVVKC--------------ARSVPAYF--------AETLYNA-MKGAGTDDDTLIRVMVTRGEVDMLDIRAEFRKLFARSLFSMIKGDTGGDYRKAL 308          
BLAST of Annexin vs. Planmine SMEST
Match: SMESG000030132.1 (SMESG000030132.1)

HSP 1 Score: 694.501 bits (1791), Expect = 0.000e+0
Identity = 338/339 (99.71%), Postives = 339/339 (100.00%), Query Frame = 1
Query:  127 MDQIGVKGERYKGTIKPFPNFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDLDYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN 1143
            MDQIGVKGERYKGTIKPFPNFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDLDYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQ+NKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN
Sbjct:    1 MDQIGVKGERYKGTIKPFPNFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDLDYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQSNKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN 339          
BLAST of Annexin vs. Planmine SMEST
Match: SMESG000042839.1 (SMESG000042839.1)

HSP 1 Score: 548.51 bits (1412), Expect = 0.000e+0
Identity = 260/339 (76.70%), Postives = 305/339 (89.97%), Query Frame = 1
Query:  127 MDQIGVKGERYKGTIKPFPNFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDLDYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN 1143
            M+ IG KGE+YKGTIKPFPNF+ E DCEVL+KAMKGIGTDEKAI+ECLGRR ++QRLEIKKTYKTMFGKDLI  LKSE+SGNF +AV ESL++ DYYDA SL  AMKGAGTRENVLTEILTSR+N QIENIK+LYKK ++ +LE++I+ ETSGFFKRVLVSCLQANKPEL+++ I+++ E G  AVV+INQA+QEA ELYNAGEKK+GTDEA+FIKIFCMRNKYQLRATFDEYEKI+GKDIF+SID+EMSGD +S +KAIAFQAVN PFYFAT+LY +MKGAGT DTTL R+L++RSEIDL NIK EF RE+  TLE+FVKDDTSGDY+A+L+RFV+GN
Sbjct:    1 MEFIGAKGEKYKGTIKPFPNFHAEQDCEVLKKAMKGIGTDEKAIVECLGRRSISQRLEIKKTYKTMFGKDLIADLKSELSGNFCQAVEESLFEPDYYDAHSLFHAMKGAGTRENVLTEILTSRTNKQIENIKVLYKKLYSVELEENIVSETSGFFKRVLVSCLQANKPELSHDDIQKLHEHGPKAVVSINQAKQEAQELYNAGEKKLGTDEAVFIKIFCMRNKYQLRATFDEYEKISGKDIFESIDNEMSGDFRSSIKAIAFQAVNTPFYFATRLYNAMKGAGTTDTTLRRILISRSEIDLENIKAEFSREYKQTLESFVKDDTSGDYQAFLLRFVQGN 339          
BLAST of Annexin vs. Planmine SMEST
Match: SMESG000023108.1 (SMESG000023108.1)

HSP 1 Score: 290.426 bits (742), Expect = 5.086e-91
Identity = 159/329 (48.33%), Postives = 208/329 (63.22%), Query Frame = 1
Query:  160 KGTIKPFPNFNVEHDCEVLRKAMKGIGTDEKAIIECLGRRCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDLDYYDAFSLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFF-NHDLEQDIIKETSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELYNAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMSGDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEIDLLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN 1143
            + T+ PFPNFN   DCE LRKAMKG+GTDE AII+ +G+R   QR+EI + +KT+ G+DLI    SE+SGNF K         D YDA  L  AMKG GT E+ L EI+ +R+N QI++ K  YK+ +   DLE+DII ETS  FKR+L+S LQA++ E              S   + N A Q+A ELY AGEKK GTDE+ F +I   R+   LRA F+EYEK++   +  +I SEMSGD+ + L        NKP YFA  L KSMKG GT+D TL+R+++TR EID++ IKK FQ E++  L  ++KDDTSGDY   L+     N
Sbjct:  412 EATLFPFPNFNANEDCEKLRKAMKGLGTDEAAIIDVMGKRSFKQRMEIVQKFKTLLGRDLIADFDSELSGNFLKICKALCIGPDEYDASELRAAMKGLGTDEDALIEIICTRTNAQIKSFKEKYKQLYATRDLEKDIISETSSNFKRLLISLLQASRDE--------------SQTFDRNLAIQDAKELYEAGEKKFGTDESKFHQIILNRSNPHLRAMFEEYEKLSKMTLEQAIKSEMSGDIMNGLVTFVRCIQNKPRYFAMALNKSMKGLGTDDRTLLRIVITRCEIDMVQIKKAFQAEYSKRLGEWIKDDTSGDYLKILLWLTGEN 726          
The following BLAST results are available for this feature:
BLAST of Annexin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ANXA75.514e-9546.77annexin A7 [Source:HGNC Symbol;Acc:HGNC:545][more]
ANXA76.519e-9544.41annexin A7 [Source:HGNC Symbol;Acc:HGNC:545][more]
ANXA51.585e-9245.03annexin A5 [Source:HGNC Symbol;Acc:HGNC:543][more]
ANXA117.832e-9245.12annexin A11 [Source:HGNC Symbol;Acc:HGNC:535][more]
ANXA112.521e-9145.12annexin A11 [Source:HGNC Symbol;Acc:HGNC:535][more]
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BLAST of Annexin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
nex-28.263e-8143.47Annexin [Source:UniProtKB/TrEMBL;Acc:Q7JMT5][more]
nex-28.263e-8143.47Annexin [Source:UniProtKB/TrEMBL;Acc:Q7JMT5][more]
nex-22.526e-8043.47Annexin [Source:UniProtKB/TrEMBL;Acc:Q7JMT5][more]
nex-11.708e-5937.20Annexin [Source:UniProtKB/TrEMBL;Acc:G5EEA8][more]
nex-11.708e-5937.20Annexin [Source:UniProtKB/TrEMBL;Acc:G5EEA8][more]
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BLAST of Annexin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
AnxB112.147e-8245.37gene:FBgn0030749 transcript:FBtr0334038[more]
AnxB112.147e-8245.37gene:FBgn0030749 transcript:FBtr0074302[more]
AnxB112.147e-8245.37gene:FBgn0030749 transcript:FBtr0334041[more]
AnxB116.065e-8045.37gene:FBgn0030749 transcript:FBtr0334040[more]
AnxB116.065e-8045.37gene:FBgn0030749 transcript:FBtr0074303[more]
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BLAST of Annexin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
anxa11a6.265e-9747.11annexin A11a [Source:ZFIN;Acc:ZDB-GENE-030707-4][more]
anxa11a2.781e-9647.11annexin A11a [Source:ZFIN;Acc:ZDB-GENE-030707-4][more]
anxa11b8.357e-9546.50annexin A11b [Source:ZFIN;Acc:ZDB-GENE-030707-5][more]
anxa42.284e-9345.87annexin A4 [Source:ZFIN;Acc:ZDB-GENE-030707-1][more]
anxa42.284e-9345.87annexin A4 [Source:ZFIN;Acc:ZDB-GENE-030707-1][more]
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BLAST of Annexin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
mllt105.157e-10149.24MLLT10, histone lysine methyltransferase DOT1L cof... [more]
mllt105.561e-10149.24MLLT10, histone lysine methyltransferase DOT1L cof... [more]
mllt101.359e-10049.24MLLT10, histone lysine methyltransferase DOT1L cof... [more]
mllt101.447e-10049.24MLLT10, histone lysine methyltransferase DOT1L cof... [more]
trpv38.913e-9847.20transient receptor potential cation channel, subfa... [more]
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BLAST of Annexin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Anxa72.695e-9646.77annexin A7 [Source:MGI Symbol;Acc:MGI:88031][more]
Anxa72.695e-9646.77annexin A7 [Source:MGI Symbol;Acc:MGI:88031][more]
Anxa73.066e-9644.01annexin A7 [Source:MGI Symbol;Acc:MGI:88031][more]
Anxa53.908e-9244.24annexin A5 [Source:MGI Symbol;Acc:MGI:106008][more]
Anxa41.761e-9145.87annexin A4 [Source:MGI Symbol;Acc:MGI:88030][more]
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BLAST of Annexin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P20072|ANXA7_BOVIN1.904e-9748.15Annexin A7 OS=Bos taurus OX=9913 GN=ANXA7 PE=1 SV=... [more]
sp|Q07076|ANXA7_MOUSE1.885e-9546.77Annexin A7 OS=Mus musculus OX=10090 GN=Anxa7 PE=1 ... [more]
sp|P20073|ANXA7_HUMAN3.130e-9444.41Annexin A7 OS=Homo sapiens OX=9606 GN=ANXA7 PE=1 S... [more]
sp|Q4R5L5|ANXA7_MACFA4.324e-9443.14Annexin A7 OS=Macaca fascicularis OX=9541 GN=ANXA7... [more]
sp|Q4R4H7|ANXA5_MACFA1.881e-9244.95Annexin A5 OS=Macaca fascicularis OX=9541 GN=ANXA5... [more]
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BLAST of Annexin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1S3JHE89.216e-11350.15Annexin OS=Lingula unguis OX=7574 GN=LOC106173262 ... [more]
A0A1S3JHA61.683e-11250.15Annexin OS=Lingula unguis OX=7574 GN=LOC106173262 ... [more]
A0A2T7PZC21.783e-11250.00Annexin OS=Pomacea canaliculata OX=400727 GN=C0Q70... [more]
F2UPY83.232e-10550.93Annexin OS=Salpingoeca rosetta (strain ATCC 50818 ... [more]
A0A210QSV83.817e-10550.15Annexin OS=Mizuhopecten yessoensis OX=6573 GN=KP79... [more]
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BLAST of Annexin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSAMXT00000004530.21.355e-9547.42annexin A11-like [Source:NCBI gene;Acc:103040502][more]
anxa41.978e-9346.60annexin A4 [Source:NCBI gene;Acc:103027730][more]
anxa11a1.774e-9245.59annexin A11 [Source:NCBI gene;Acc:103039162][more]
anxa5b4.016e-9045.73annexin A5-like [Source:NCBI gene;Acc:103025290][more]
anxa65.167e-8841.69annexin A6 [Source:NCBI gene;Acc:103026042][more]
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BLAST of Annexin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ANXA72.730e-10047.56annexin A7 [Source:HGNC Symbol;Acc:HGNC:545][more]
ANXA77.900e-9545.85annexin A7 [Source:HGNC Symbol;Acc:HGNC:545][more]
ENSPMAT00000001517.12.719e-8945.37pep scaffold:Pmarinus_7.0:GL476341:319620:335761:1... [more]
ANXA116.269e-8543.20annexin A11 [Source:HGNC Symbol;Acc:HGNC:535][more]
anxa2a1.429e-5635.91annexin A2a [Source:ZFIN;Acc:ZDB-GENE-030131-4282][more]
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BLAST of Annexin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Annexin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO284441.111e-8846.41Annexin [Source:UniProtKB/TrEMBL;Acc:A7T6G0][more]
EDO320433.987e-8844.31Annexin [Source:UniProtKB/TrEMBL;Acc:A7SW86][more]
EDO440518.211e-7339.33Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO297571.800e-3939.50Annexin [Source:UniProtKB/TrEMBL;Acc:A7T2R2][more]
EDO440492.806e-2939.77Annexin [Source:UniProtKB/TrEMBL;Acc:A7RWX1][more]
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BLAST of Annexin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
anxa11a1.041e-9848.01annexin A5 [Source:NCBI gene;Acc:101174691][more]
anxa46.836e-9345.57annexin A4 [Source:NCBI gene;Acc:100049454][more]
anxa112.049e-9247.24annexin max4 [Source:NCBI gene;Acc:100049456][more]
anxa114.800e-9247.24annexin max4 [Source:NCBI gene;Acc:100049456][more]
anxa108.822e-9246.34annexin A10 [Source:NCBI gene;Acc:100049533][more]
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BLAST of Annexin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 3
Match NameE-valueIdentityDescription
SMESG000030132.10.000e+099.71SMESG000030132.1[more]
SMESG000042839.10.000e+076.70SMESG000042839.1[more]
SMESG000023108.15.086e-9148.33SMESG000023108.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30020215 ID=SMED30020215|Name=Annexin|organism=Schmidtea mediterranea sexual|type=transcript|length=1235bp
GAAGAGTTTATCGGTTTCGATTATTGTCTGATAACAAAACGCATTTTCAG
TGATTACTATAGCGTATCTATAAAAGATTTACCAAGTTCTGAATTTATCA
TTATCAAACCTTTAAGCTCAAGATAAATGGATCAAATCGGAGTCAAAGGA
GAACGTTATAAAGGCACAATTAAACCTTTCCCAAATTTTAATGTTGAACA
CGATTGTGAGGTCCTTAGGAAAGCTATGAAAGGAATTGGTACTGATGAAA
AAGCAATCATTGAATGTCTGGGTCGCAGATGTCTTGCACAGAGATTAGAA
ATTAAGAAGACATATAAAACCATGTTTGGAAAGGATTTGATAGAAGCTCT
TAAATCTGAAATCAGTGGGAACTTTAAAAAGGCCGTCATTGAATCACTAT
ACGATCTAGATTATTACGACGCTTTCAGTCTGCACGAAGCAATGAAAGGA
GCTGGAACTAGAGAAAATGTTCTGACTGAAATTTTGACTTCCAGATCAAA
TCATCAAATTGAAAATATAAAAATTCTTTACAAAAAATTTTTCAACCACG
ATCTGGAACAAGACATTATCAAGGAAACAAGTGGATTTTTTAAGCGAGTC
CTTGTATCATGTTTGCAAGCGAATAAACCCGAATTGACAAACGAACAAAT
AAGAGAAGTCCAAGAAAGAGGAATTTCGGCAGTTGTCAACATTAATCAAG
CCAGACAAGAGGCGACTGAGTTGTACAACGCTGGAGAGAAAAAAATTGGA
ACTGACGAGGCAATGTTCATAAAAATATTCTGTATGAGAAACAAATATCA
GCTTCGAGCGACCTTTGATGAATATGAAAAGATTGCCGGAAAAGATATTT
TCGATTCCATAGATAGTGAAATGTCGGGAGATTTGCAATCGGTCCTGAAA
GCCATCGCCTTTCAAGCGGTCAATAAGCCATTCTATTTTGCCACAAAATT
GTATAAGTCTATGAAAGGAGCAGGAACAAATGACACAACTTTAGTAAGAG
TGTTGCTAACTCGAAGTGAAATTGACTTATTAAACATCAAGAAAGAGTTT
CAAAGAGAATTCAATGATACTTTGGAAAATTTCGTTAAAGACGACACTTC
CGGAGATTATAGAGCTTATCTGATGAGATTTGTGGAAGGAAACTAAGATA
GTAGATAATTACTATGGATTCTAATTCTACTAATTTTATTTTAAAATTCG
GTTGTAGTTAATAAAAAGTTTCACTTTAAAAAAAA
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protein sequence of SMED30020215-orf-1

>SMED30020215-orf-1 ID=SMED30020215-orf-1|Name=SMED30020215-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=340bp
MDQIGVKGERYKGTIKPFPNFNVEHDCEVLRKAMKGIGTDEKAIIECLGR
RCLAQRLEIKKTYKTMFGKDLIEALKSEISGNFKKAVIESLYDLDYYDAF
SLHEAMKGAGTRENVLTEILTSRSNHQIENIKILYKKFFNHDLEQDIIKE
TSGFFKRVLVSCLQANKPELTNEQIREVQERGISAVVNINQARQEATELY
NAGEKKIGTDEAMFIKIFCMRNKYQLRATFDEYEKIAGKDIFDSIDSEMS
GDLQSVLKAIAFQAVNKPFYFATKLYKSMKGAGTNDTTLVRVLLTRSEID
LLNIKKEFQREFNDTLENFVKDDTSGDYRAYLMRFVEGN*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000020protonephridia
PLANA:0000034epidermis
PLANA:0000418head
PLANA:0002032epidermal cell
Vocabulary: INTERPRO
TermDefinition
IPR037104Annexin_sf
IPR001464Annexin
IPR018502Annexin_repeat
IPR018252Annexin_repeat_CS
Vocabulary: molecular function
TermDefinition
GO:0005509calcium ion binding
GO:0005544calcium-dependent phospholipid binding
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001464AnnexinPRINTSPR00196ANNEXINcoord: 279..299
score: 60.14
coord: 35..57
score: 51.53
coord: 75..91
score: 38.34
coord: 102..123
score: 62.21
coord: 323..336
score: 47.62
IPR018502Annexin repeatSMARTSM00335annex3coord: 208..260
e-value: 1.4E-13
score: 61.1
coord: 110..162
e-value: 6.3E-17
score: 72.2
coord: 38..90
e-value: 3.5E-18
score: 76.4
coord: 283..335
e-value: 7.0E-14
score: 62.1
IPR018502Annexin repeatPFAMPF00191Annexincoord: 195..260
e-value: 3.8E-21
score: 74.9
coord: 270..333
e-value: 1.8E-19
score: 69.5
coord: 26..88
e-value: 4.4E-22
score: 77.9
coord: 97..161
e-value: 1.3E-20
score: 73.2
IPR037104Annexin superfamilyGENE3DG3DSA:1.10.220.10coord: 20..91
e-value: 1.1E-26
score: 94.7
IPR037104Annexin superfamilyGENE3DG3DSA:1.10.220.10coord: 267..339
e-value: 3.6E-23
score: 83.5
IPR037104Annexin superfamilyGENE3DG3DSA:1.10.220.10coord: 183..263
e-value: 3.8E-24
score: 86.6
IPR037104Annexin superfamilyGENE3DG3DSA:1.10.220.10coord: 95..165
e-value: 1.4E-24
score: 88.0
IPR037104Annexin superfamilySUPERFAMILYSSF47874Annexincoord: 5..334
NoneNo IPR availablePANTHERPTHR10502:SF181coord: 7..336
NoneNo IPR availablePANTHERPTHR10502ANNEXINcoord: 7..336
NoneNo IPR availablePROSITEPS51897ANNEXIN_2coord: 266..337
score: 21.805
NoneNo IPR availablePROSITEPS51897ANNEXIN_2coord: 190..262
score: 23.798
NoneNo IPR availablePROSITEPS51897ANNEXIN_2coord: 93..164
score: 26.911
NoneNo IPR availablePROSITEPS51897ANNEXIN_2coord: 21..92
score: 24.933
IPR018252Annexin repeat, conserved sitePROSITEPS00223ANNEXIN_1coord: 283..335