Protein kinase C

Overview
NameProtein kinase C
Smed IDSMED30020212
Length (bp)1264
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Protein kinase C (SMED30020212) t-SNE clustered cells

Violin plots show distribution of expression levels for Protein kinase C (SMED30020212) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Protein kinase C (SMED30020212) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Protein kinase C (SMED30020212) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30020212

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 5

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
nervous systemSMED30020212h1SMcG0022777 dd_Smed_v4_4464_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30020212h1SMcG0022777 dd_Smed_v4_4464_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30020212h1SMcG0022777 dd_Smed_v4_4464_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30020212h1SMcG0022777 dd_Smed_v4_4464_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30020212h1SMcG0022777 dd_Smed_v4_4464_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Protein kinase C vs. Ensembl Human
Match: PRKCA (protein kinase C alpha [Source:HGNC Symbol;Acc:HGNC:9393])

HSP 1 Score: 130.954 bits (328), Expect = 3.444e-34
Identity = 63/95 (66.32%), Postives = 77/95 (81.05%), Query Frame = 3
Query:  978 CDMNVHGKCEKNVPCLCGVDHTERRGRIHIIVRLERLKLHVTVVESKNLVPMDPNGLADPYVKIKLTPSDDQSGKKFKTKTIRSSLNPVWNESFT 1262
            CDMNVH +C  NVP LCG+DHTE+RGRI++   +   KLHVTV ++KNL+PMDPNGL+DPYVK+KL P D ++  K KTKTIRS+LNP WNESFT
Sbjct:  135 CDMNVHKQCVINVPSLCGMDHTEKRGRIYLKAEVADEKLHVTVRDAKNLIPMDPNGLSDPYVKLKLIP-DPKNESKQKTKTIRSTLNPQWNESFT 228          
BLAST of Protein kinase C vs. Ensembl Human
Match: PRKCG (protein kinase C gamma [Source:HGNC Symbol;Acc:HGNC:9402])

HSP 1 Score: 121.709 bits (304), Expect = 3.512e-33
Identity = 56/95 (58.95%), Postives = 78/95 (82.11%), Query Frame = 3
Query:  978 CDMNVHGKCEKNVPCLCGVDHTERRGRIHIIVRLERL-KLHVTVVESKNLVPMDPNGLADPYVKIKLTPSDDQSGKKFKTKTIRSSLNPVWNESF 1259
            C+MNVH +C ++VP LCGVDHTERRGR+ + +R     ++HVTV E++NL+PMDPNGL+DPYVK+KL P D ++  K KT+T++++LNPVWNE+F
Sbjct:    6 CEMNVHRRCVRSVPSLCGVDHTERRGRLQLEIRAPTADEIHVTVGEARNLIPMDPNGLSDPYVKLKLIP-DPRNLTKQKTRTVKATLNPVWNETF 99          
BLAST of Protein kinase C vs. Ensembl Human
Match: PRKCA (protein kinase C alpha [Source:HGNC Symbol;Acc:HGNC:9393])

HSP 1 Score: 132.109 bits (331), Expect = 1.052e-32
Identity = 63/95 (66.32%), Postives = 77/95 (81.05%), Query Frame = 3
Query:  978 CDMNVHGKCEKNVPCLCGVDHTERRGRIHIIVRLERLKLHVTVVESKNLVPMDPNGLADPYVKIKLTPSDDQSGKKFKTKTIRSSLNPVWNESFT 1262
            CDMNVH +C  NVP LCG+DHTE+RGRI++   +   KLHVTV ++KNL+PMDPNGL+DPYVK+KL P D ++  K KTKTIRS+LNP WNESFT
Sbjct:  135 CDMNVHKQCVINVPSLCGMDHTEKRGRIYLKAEVADEKLHVTVRDAKNLIPMDPNGLSDPYVKLKLIP-DPKNESKQKTKTIRSTLNPQWNESFT 228          
BLAST of Protein kinase C vs. Ensembl Human
Match: PRKCB (protein kinase C beta [Source:HGNC Symbol;Acc:HGNC:9395])

HSP 1 Score: 122.094 bits (305), Expect = 2.399e-29
Identity = 61/94 (64.89%), Postives = 72/94 (76.60%), Query Frame = 3
Query:  978 CDMNVHGKCEKNVPCLCGVDHTERRGRIHIIVRLERLKLHVTVVESKNLVPMDPNGLADPYVKIKLTPSDDQSGKKFKTKTIRSSLNPVWNESF 1259
            C MNVH +C  NVP LCG DHTERRGRI+I   ++R  L V V ++KNLVPMDPNGL+DPYVK+KL P D +S  K KTKTI+ SLNP WNE+F
Sbjct:  135 CMMNVHKRCVMNVPSLCGTDHTERRGRIYIQAHIDRDVLIVLVRDAKNLVPMDPNGLSDPYVKLKLIP-DPKSESKQKTKTIKCSLNPEWNETF 227          
BLAST of Protein kinase C vs. Ensembl Human
Match: PRKCB (protein kinase C beta [Source:HGNC Symbol;Acc:HGNC:9395])

HSP 1 Score: 122.094 bits (305), Expect = 2.673e-29
Identity = 61/94 (64.89%), Postives = 72/94 (76.60%), Query Frame = 3
Query:  978 CDMNVHGKCEKNVPCLCGVDHTERRGRIHIIVRLERLKLHVTVVESKNLVPMDPNGLADPYVKIKLTPSDDQSGKKFKTKTIRSSLNPVWNESF 1259
            C MNVH +C  NVP LCG DHTERRGRI+I   ++R  L V V ++KNLVPMDPNGL+DPYVK+KL P D +S  K KTKTI+ SLNP WNE+F
Sbjct:  135 CMMNVHKRCVMNVPSLCGTDHTERRGRIYIQAHIDRDVLIVLVRDAKNLVPMDPNGLSDPYVKLKLIP-DPKSESKQKTKTIKCSLNPEWNETF 227          
BLAST of Protein kinase C vs. Ensembl Celegans
Match: pkc-2 (Protein kinase C-like 2 [Source:UniProtKB/Swiss-Prot;Acc:P90980])

HSP 1 Score: 123.635 bits (309), Expect = 2.791e-30
Identity = 55/95 (57.89%), Postives = 72/95 (75.79%), Query Frame = 3
Query:  978 CDMNVHGKCEKNVPCLCGVDHTERRGRIHIIVRLERLKLHVTVVESKNLVPMDPNGLADPYVKIKLTPSDDQSGKKFKTKTIRSSLNPVWNESFT 1262
            CD NVH +C KNVP +CG D+TE+RGR+ I   +E  +L + ++E+KNL+PMDPNGL+DPYVK KL P D     K KTKT+R++LNP WNE+FT
Sbjct:  137 CDTNVHHRCVKNVPNMCGTDNTEKRGRLRIEAHIENDQLTIKILEAKNLIPMDPNGLSDPYVKCKLIPEDSGCKSKQKTKTLRATLNPQWNETFT 231          
BLAST of Protein kinase C vs. Ensembl Celegans
Match: pkc-2 (Protein kinase C-like 2 [Source:UniProtKB/Swiss-Prot;Acc:P90980])

HSP 1 Score: 123.635 bits (309), Expect = 3.278e-30
Identity = 55/95 (57.89%), Postives = 72/95 (75.79%), Query Frame = 3
Query:  978 CDMNVHGKCEKNVPCLCGVDHTERRGRIHIIVRLERLKLHVTVVESKNLVPMDPNGLADPYVKIKLTPSDDQSGKKFKTKTIRSSLNPVWNESFT 1262
            CD NVH +C KNVP +CG D+TE+RGR+ I   +E  +L + ++E+KNL+PMDPNGL+DPYVK KL P D     K KTKT+R++LNP WNE+FT
Sbjct:  182 CDTNVHHRCVKNVPNMCGTDNTEKRGRLRIEAHIENDQLTIKILEAKNLIPMDPNGLSDPYVKCKLIPEDSGCKSKQKTKTLRATLNPQWNETFT 276          
BLAST of Protein kinase C vs. Ensembl Celegans
Match: pkc-2 (Protein kinase C-like 2 [Source:UniProtKB/Swiss-Prot;Acc:P90980])

HSP 1 Score: 123.25 bits (308), Expect = 3.352e-30
Identity = 55/95 (57.89%), Postives = 72/95 (75.79%), Query Frame = 3
Query:  978 CDMNVHGKCEKNVPCLCGVDHTERRGRIHIIVRLERLKLHVTVVESKNLVPMDPNGLADPYVKIKLTPSDDQSGKKFKTKTIRSSLNPVWNESFT 1262
            CD NVH +C KNVP +CG D+TE+RGR+ I   +E  +L + ++E+KNL+PMDPNGL+DPYVK KL P D     K KTKT+R++LNP WNE+FT
Sbjct:  137 CDTNVHHRCVKNVPNMCGTDNTEKRGRLRIEAHIENDQLTIKILEAKNLIPMDPNGLSDPYVKCKLIPEDSGCKSKQKTKTLRATLNPQWNETFT 231          
BLAST of Protein kinase C vs. Ensembl Celegans
Match: pkc-2 (Protein kinase C-like 2 [Source:UniProtKB/Swiss-Prot;Acc:P90980])

HSP 1 Score: 123.635 bits (309), Expect = 3.542e-30
Identity = 55/95 (57.89%), Postives = 72/95 (75.79%), Query Frame = 3
Query:  978 CDMNVHGKCEKNVPCLCGVDHTERRGRIHIIVRLERLKLHVTVVESKNLVPMDPNGLADPYVKIKLTPSDDQSGKKFKTKTIRSSLNPVWNESFT 1262
            CD NVH +C KNVP +CG D+TE+RGR+ I   +E  +L + ++E+KNL+PMDPNGL+DPYVK KL P D     K KTKT+R++LNP WNE+FT
Sbjct:  277 CDTNVHHRCVKNVPNMCGTDNTEKRGRLRIEAHIENDQLTIKILEAKNLIPMDPNGLSDPYVKCKLIPEDSGCKSKQKTKTLRATLNPQWNETFT 371          
BLAST of Protein kinase C vs. Ensembl Celegans
Match: snt-2 (Synaptotagmin 2 [Source:UniProtKB/Swiss-Prot;Acc:K8FE10])

HSP 1 Score: 63.929 bits (154), Expect = 5.882e-11
Identity = 33/74 (44.59%), Postives = 49/74 (66.22%), Query Frame = 3
Query: 1044 ERRGRIHIIVR--LERLKLHVTVVESKNLVPMDPNGLADPYVKIKLTPSDDQSGKKFKTKTIRSSLNPVWNESF 1259
            ++ G IH  V    E+ KL VT+V + +L  MD NG++DPYVK+ + P   Q   KF+T+ IR++LNP +NE+F
Sbjct:   82 KQYGNIHFRVEYDFEQSKLSVTIVSASDLPAMDRNGMSDPYVKVYVLPERKQ---KFETRIIRNTLNPTYNETF 152          
BLAST of Protein kinase C vs. Ensembl Fly
Match: Pkc53E (gene:FBgn0003091 transcript:FBtr0331960)

HSP 1 Score: 127.102 bits (318), Expect = 2.270e-31
Identity = 57/95 (60.00%), Postives = 74/95 (77.89%), Query Frame = 3
Query:  978 CDMNVHGKCEKNVPCLCGVDHTERRGRIHIIVRLERLKLHVTVVESKNLVPMDPNGLADPYVKIKLTPSDDQSGKKFKTKTIRSSLNPVWNESFT 1262
            CDMNVH +C++NVP LCG DHTERRGRI++ + ++   L V + E +NL+PMDPNGL+DPYVK+KL P D    KK KT+TI++ LNPVWNE+ T
Sbjct:  144 CDMNVHARCKENVPSLCGCDHTERRGRIYLEINVKENLLTVQIKEGRNLIPMDPNGLSDPYVKVKLIPDDKDQSKK-KTRTIKACLNPVWNETLT 237          
BLAST of Protein kinase C vs. Ensembl Fly
Match: Pkc53E (gene:FBgn0003091 transcript:FBtr0087049)

HSP 1 Score: 127.102 bits (318), Expect = 2.270e-31
Identity = 57/95 (60.00%), Postives = 74/95 (77.89%), Query Frame = 3
Query:  978 CDMNVHGKCEKNVPCLCGVDHTERRGRIHIIVRLERLKLHVTVVESKNLVPMDPNGLADPYVKIKLTPSDDQSGKKFKTKTIRSSLNPVWNESFT 1262
            CDMNVH +C++NVP LCG DHTERRGRI++ + ++   L V + E +NL+PMDPNGL+DPYVK+KL P D    KK KT+TI++ LNPVWNE+ T
Sbjct:  144 CDMNVHARCKENVPSLCGCDHTERRGRIYLEINVKENLLTVQIKEGRNLIPMDPNGLSDPYVKVKLIPDDKDQSKK-KTRTIKACLNPVWNETLT 237          
BLAST of Protein kinase C vs. Ensembl Fly
Match: Pkc53E (gene:FBgn0003091 transcript:FBtr0087048)

HSP 1 Score: 127.102 bits (318), Expect = 2.333e-31
Identity = 57/95 (60.00%), Postives = 74/95 (77.89%), Query Frame = 3
Query:  978 CDMNVHGKCEKNVPCLCGVDHTERRGRIHIIVRLERLKLHVTVVESKNLVPMDPNGLADPYVKIKLTPSDDQSGKKFKTKTIRSSLNPVWNESFT 1262
            CDMNVH +C++NVP LCG DHTERRGRI++ + ++   L V + E +NL+PMDPNGL+DPYVK+KL P D    KK KT+TI++ LNPVWNE+ T
Sbjct:  153 CDMNVHARCKENVPSLCGCDHTERRGRIYLEINVKENLLTVQIKEGRNLIPMDPNGLSDPYVKVKLIPDDKDQSKK-KTRTIKACLNPVWNETLT 246          
BLAST of Protein kinase C vs. Ensembl Fly
Match: Pkc53E (gene:FBgn0003091 transcript:FBtr0112819)

HSP 1 Score: 127.102 bits (318), Expect = 2.462e-31
Identity = 57/95 (60.00%), Postives = 74/95 (77.89%), Query Frame = 3
Query:  978 CDMNVHGKCEKNVPCLCGVDHTERRGRIHIIVRLERLKLHVTVVESKNLVPMDPNGLADPYVKIKLTPSDDQSGKKFKTKTIRSSLNPVWNESFT 1262
            CDMNVH +C++NVP LCG DHTERRGRI++ + ++   L V + E +NL+PMDPNGL+DPYVK+KL P D    KK KT+TI++ LNPVWNE+ T
Sbjct:  152 CDMNVHARCKENVPSLCGCDHTERRGRIYLEINVKENLLTVQIKEGRNLIPMDPNGLSDPYVKVKLIPDDKDQSKK-KTRTIKACLNPVWNETLT 245          
BLAST of Protein kinase C vs. Ensembl Fly
Match: Pkc53E (gene:FBgn0003091 transcript:FBtr0305070)

HSP 1 Score: 127.102 bits (318), Expect = 2.462e-31
Identity = 57/95 (60.00%), Postives = 74/95 (77.89%), Query Frame = 3
Query:  978 CDMNVHGKCEKNVPCLCGVDHTERRGRIHIIVRLERLKLHVTVVESKNLVPMDPNGLADPYVKIKLTPSDDQSGKKFKTKTIRSSLNPVWNESFT 1262
            CDMNVH +C++NVP LCG DHTERRGRI++ + ++   L V + E +NL+PMDPNGL+DPYVK+KL P D    KK KT+TI++ LNPVWNE+ T
Sbjct:  152 CDMNVHARCKENVPSLCGCDHTERRGRIYLEINVKENLLTVQIKEGRNLIPMDPNGLSDPYVKVKLIPDDKDQSKK-KTRTIKACLNPVWNETLT 245          
BLAST of Protein kinase C vs. Ensembl Zebrafish
Match: prkcg (protein kinase C, gamma [Source:ZFIN;Acc:ZDB-GENE-090206-1])

HSP 1 Score: 134.806 bits (338), Expect = 6.114e-34
Identity = 63/95 (66.32%), Postives = 78/95 (82.11%), Query Frame = 3
Query:  978 CDMNVHGKCEKNVPCLCGVDHTERRGRIHIIVRLERLKLHVTVVESKNLVPMDPNGLADPYVKIKLTPSDDQSGKKFKTKTIRSSLNPVWNESFT 1262
            CDMNVH +CE +VP LCG DHTE+RGRI + VR E+  +++TV E+ NL+PMDPNGL+DPYVK+KL P D +S  K KTKTIRS+LNP+WNESFT
Sbjct:  114 CDMNVHKRCESSVPSLCGQDHTEKRGRIRLTVRGEKEDIYITVHEALNLIPMDPNGLSDPYVKLKLIP-DPKSHSKQKTKTIRSTLNPIWNESFT 207          
BLAST of Protein kinase C vs. Ensembl Zebrafish
Match: prkcaa (protein kinase C, alpha, a [Source:ZFIN;Acc:ZDB-GENE-050208-100])

HSP 1 Score: 132.494 bits (332), Expect = 4.335e-33
Identity = 63/95 (66.32%), Postives = 76/95 (80.00%), Query Frame = 3
Query:  978 CDMNVHGKCEKNVPCLCGVDHTERRGRIHIIVRLERLKLHVTVVESKNLVPMDPNGLADPYVKIKLTPSDDQSGKKFKTKTIRSSLNPVWNESFT 1262
            CDMNVH +C  NVP LCG DHTERRGR+++ + +   K+HVTV E KNL+PMDPNGL+DPYVK+KL P D ++  K KTKTIRSSLNP WNE+FT
Sbjct:  133 CDMNVHKQCVMNVPSLCGTDHTERRGRLYMKIEVIGDKMHVTVGEGKNLIPMDPNGLSDPYVKLKLIP-DPKNETKQKTKTIRSSLNPTWNETFT 226          
BLAST of Protein kinase C vs. Ensembl Zebrafish
Match: prkcaa (protein kinase C, alpha, a [Source:ZFIN;Acc:ZDB-GENE-050208-100])

HSP 1 Score: 132.494 bits (332), Expect = 4.806e-33
Identity = 63/95 (66.32%), Postives = 76/95 (80.00%), Query Frame = 3
Query:  978 CDMNVHGKCEKNVPCLCGVDHTERRGRIHIIVRLERLKLHVTVVESKNLVPMDPNGLADPYVKIKLTPSDDQSGKKFKTKTIRSSLNPVWNESFT 1262
            CDMNVH +C  NVP LCG DHTERRGR+++ + +   K+HVTV E KNL+PMDPNGL+DPYVK+KL P D ++  K KTKTIRSSLNP WNE+FT
Sbjct:  133 CDMNVHKQCVMNVPSLCGTDHTERRGRLYMKIEVIGDKMHVTVGEGKNLIPMDPNGLSDPYVKLKLIP-DPKNETKQKTKTIRSSLNPTWNETFT 226          
BLAST of Protein kinase C vs. Ensembl Zebrafish
Match: prkcab (protein kinase C, alpha, b [Source:ZFIN;Acc:ZDB-GENE-131121-412])

HSP 1 Score: 131.339 bits (329), Expect = 8.814e-33
Identity = 62/94 (65.96%), Postives = 75/94 (79.79%), Query Frame = 3
Query:  978 CDMNVHGKCEKNVPCLCGVDHTERRGRIHIIVRLERLKLHVTVVESKNLVPMDPNGLADPYVKIKLTPSDDQSGKKFKTKTIRSSLNPVWNESF 1259
            CDMNVH +C  NVP LCG DHTERRGRI + + +   +LHVTV E++NL+PMDPNGL+DPYVK+KL P D ++  K KT+TIRSSLNP WNESF
Sbjct:   87 CDMNVHKQCVMNVPSLCGTDHTERRGRIFMKIEVSGDRLHVTVGEARNLIPMDPNGLSDPYVKLKLIP-DPKNETKQKTRTIRSSLNPTWNESF 179          
BLAST of Protein kinase C vs. Ensembl Zebrafish
Match: prkcab (protein kinase C, alpha, b [Source:ZFIN;Acc:ZDB-GENE-131121-412])

HSP 1 Score: 131.339 bits (329), Expect = 1.001e-32
Identity = 62/94 (65.96%), Postives = 75/94 (79.79%), Query Frame = 3
Query:  978 CDMNVHGKCEKNVPCLCGVDHTERRGRIHIIVRLERLKLHVTVVESKNLVPMDPNGLADPYVKIKLTPSDDQSGKKFKTKTIRSSLNPVWNESF 1259
            CDMNVH +C  NVP LCG DHTERRGRI + + +   +LHVTV E++NL+PMDPNGL+DPYVK+KL P D ++  K KT+TIRSSLNP WNESF
Sbjct:   87 CDMNVHKQCVMNVPSLCGTDHTERRGRIFMKIEVSGDRLHVTVGEARNLIPMDPNGLSDPYVKLKLIP-DPKNETKQKTRTIRSSLNPTWNESF 179          
BLAST of Protein kinase C vs. Ensembl Xenopus
Match: prkcb (protein kinase C beta [Source:NCBI gene;Acc:100038043])

HSP 1 Score: 125.176 bits (313), Expect = 1.484e-30
Identity = 62/94 (65.96%), Postives = 71/94 (75.53%), Query Frame = 3
Query:  978 CDMNVHGKCEKNVPCLCGVDHTERRGRIHIIVRLERLKLHVTVVESKNLVPMDPNGLADPYVKIKLTPSDDQSGKKFKTKTIRSSLNPVWNESF 1259
            C MNVH +C  NVP LCG DHTERRGRIHI   +    L VTV +++NLVPMDPNGL+DPYVK+KL P D +S  K KTKTI+ SLNP WNESF
Sbjct:  118 CMMNVHKRCVMNVPSLCGTDHTERRGRIHIKAEIREEVLTVTVGDARNLVPMDPNGLSDPYVKLKLIP-DPKSESKQKTKTIKCSLNPTWNESF 210          
BLAST of Protein kinase C vs. Ensembl Xenopus
Match: prkcb (protein kinase C beta [Source:NCBI gene;Acc:100038043])

HSP 1 Score: 125.176 bits (313), Expect = 1.723e-30
Identity = 62/94 (65.96%), Postives = 71/94 (75.53%), Query Frame = 3
Query:  978 CDMNVHGKCEKNVPCLCGVDHTERRGRIHIIVRLERLKLHVTVVESKNLVPMDPNGLADPYVKIKLTPSDDQSGKKFKTKTIRSSLNPVWNESF 1259
            C MNVH +C  NVP LCG DHTERRGRIHI   +    L VTV +++NLVPMDPNGL+DPYVK+KL P D +S  K KTKTI+ SLNP WNESF
Sbjct:  118 CMMNVHKRCVMNVPSLCGTDHTERRGRIHIKAEIREEVLTVTVGDARNLVPMDPNGLSDPYVKLKLIP-DPKSESKQKTKTIKCSLNPTWNESF 210          
BLAST of Protein kinase C vs. Ensembl Xenopus
Match: prkcb (protein kinase C beta [Source:NCBI gene;Acc:100038043])

HSP 1 Score: 125.176 bits (313), Expect = 1.783e-30
Identity = 62/94 (65.96%), Postives = 71/94 (75.53%), Query Frame = 3
Query:  978 CDMNVHGKCEKNVPCLCGVDHTERRGRIHIIVRLERLKLHVTVVESKNLVPMDPNGLADPYVKIKLTPSDDQSGKKFKTKTIRSSLNPVWNESF 1259
            C MNVH +C  NVP LCG DHTERRGRIHI   +    L VTV +++NLVPMDPNGL+DPYVK+KL P D +S  K KTKTI+ SLNP WNESF
Sbjct:   99 CMMNVHKRCVMNVPSLCGTDHTERRGRIHIKAEIREEVLTVTVGDARNLVPMDPNGLSDPYVKLKLIP-DPKSESKQKTKTIKCSLNPTWNESF 191          
BLAST of Protein kinase C vs. Ensembl Xenopus
Match: prkcb (protein kinase C beta [Source:NCBI gene;Acc:100038043])

HSP 1 Score: 125.176 bits (313), Expect = 1.887e-30
Identity = 62/94 (65.96%), Postives = 71/94 (75.53%), Query Frame = 3
Query:  978 CDMNVHGKCEKNVPCLCGVDHTERRGRIHIIVRLERLKLHVTVVESKNLVPMDPNGLADPYVKIKLTPSDDQSGKKFKTKTIRSSLNPVWNESF 1259
            C MNVH +C  NVP LCG DHTERRGRIHI   +    L VTV +++NLVPMDPNGL+DPYVK+KL P D +S  K KTKTI+ SLNP WNESF
Sbjct:  129 CMMNVHKRCVMNVPSLCGTDHTERRGRIHIKAEIREEVLTVTVGDARNLVPMDPNGLSDPYVKLKLIP-DPKSESKQKTKTIKCSLNPTWNESF 221          
BLAST of Protein kinase C vs. Ensembl Xenopus
Match: prkcb (protein kinase C beta [Source:NCBI gene;Acc:100038043])

HSP 1 Score: 125.176 bits (313), Expect = 1.964e-30
Identity = 62/94 (65.96%), Postives = 71/94 (75.53%), Query Frame = 3
Query:  978 CDMNVHGKCEKNVPCLCGVDHTERRGRIHIIVRLERLKLHVTVVESKNLVPMDPNGLADPYVKIKLTPSDDQSGKKFKTKTIRSSLNPVWNESF 1259
            C MNVH +C  NVP LCG DHTERRGRIHI   +    L VTV +++NLVPMDPNGL+DPYVK+KL P D +S  K KTKTI+ SLNP WNESF
Sbjct:  133 CMMNVHKRCVMNVPSLCGTDHTERRGRIHIKAEIREEVLTVTVGDARNLVPMDPNGLSDPYVKLKLIP-DPKSESKQKTKTIKCSLNPTWNESF 225          
BLAST of Protein kinase C vs. Ensembl Mouse
Match: Prkca (protein kinase C, alpha [Source:MGI Symbol;Acc:MGI:97595])

HSP 1 Score: 131.724 bits (330), Expect = 8.729e-33
Identity = 63/95 (66.32%), Postives = 77/95 (81.05%), Query Frame = 3
Query:  978 CDMNVHGKCEKNVPCLCGVDHTERRGRIHIIVRLERLKLHVTVVESKNLVPMDPNGLADPYVKIKLTPSDDQSGKKFKTKTIRSSLNPVWNESFT 1262
            CDMNVH +C  NVP LCG+DHTE+RGRI++   +   KLHVTV ++KNL+PMDPNGL+DPYVK+KL P D ++  K KTKTIRS+LNP WNESFT
Sbjct:  135 CDMNVHKQCVINVPSLCGMDHTEKRGRIYLKAEVTDEKLHVTVRDAKNLIPMDPNGLSDPYVKLKLIP-DPKNESKQKTKTIRSTLNPQWNESFT 228          
BLAST of Protein kinase C vs. Ensembl Mouse
Match: Prkcb (protein kinase C, beta [Source:MGI Symbol;Acc:MGI:97596])

HSP 1 Score: 122.865 bits (307), Expect = 9.470e-30
Identity = 61/94 (64.89%), Postives = 72/94 (76.60%), Query Frame = 3
Query:  978 CDMNVHGKCEKNVPCLCGVDHTERRGRIHIIVRLERLKLHVTVVESKNLVPMDPNGLADPYVKIKLTPSDDQSGKKFKTKTIRSSLNPVWNESF 1259
            C MNVH +C  NVP LCG DHTERRGRI+I   ++R  L V V ++KNLVPMDPNGL+DPYVK+KL P D +S  K KTKTI+ SLNP WNE+F
Sbjct:  135 CMMNVHKRCVMNVPSLCGTDHTERRGRIYIQAHIDREVLIVVVRDAKNLVPMDPNGLSDPYVKLKLIP-DPKSESKQKTKTIKCSLNPEWNETF 227          
BLAST of Protein kinase C vs. Ensembl Mouse
Match: Prkcb (protein kinase C, beta [Source:MGI Symbol;Acc:MGI:97596])

HSP 1 Score: 122.479 bits (306), Expect = 1.127e-29
Identity = 61/94 (64.89%), Postives = 72/94 (76.60%), Query Frame = 3
Query:  978 CDMNVHGKCEKNVPCLCGVDHTERRGRIHIIVRLERLKLHVTVVESKNLVPMDPNGLADPYVKIKLTPSDDQSGKKFKTKTIRSSLNPVWNESF 1259
            C MNVH +C  NVP LCG DHTERRGRI+I   ++R  L V V ++KNLVPMDPNGL+DPYVK+KL P D +S  K KTKTI+ SLNP WNE+F
Sbjct:  135 CMMNVHKRCVMNVPSLCGTDHTERRGRIYIQAHIDREVLIVVVRDAKNLVPMDPNGLSDPYVKLKLIP-DPKSESKQKTKTIKCSLNPEWNETF 227          
BLAST of Protein kinase C vs. Ensembl Mouse
Match: Prkcb (protein kinase C, beta [Source:MGI Symbol;Acc:MGI:97596])

HSP 1 Score: 122.479 bits (306), Expect = 1.127e-29
Identity = 61/94 (64.89%), Postives = 72/94 (76.60%), Query Frame = 3
Query:  978 CDMNVHGKCEKNVPCLCGVDHTERRGRIHIIVRLERLKLHVTVVESKNLVPMDPNGLADPYVKIKLTPSDDQSGKKFKTKTIRSSLNPVWNESF 1259
            C MNVH +C  NVP LCG DHTERRGRI+I   ++R  L V V ++KNLVPMDPNGL+DPYVK+KL P D +S  K KTKTI+ SLNP WNE+F
Sbjct:  135 CMMNVHKRCVMNVPSLCGTDHTERRGRIYIQAHIDREVLIVVVRDAKNLVPMDPNGLSDPYVKLKLIP-DPKSESKQKTKTIKCSLNPEWNETF 227          
BLAST of Protein kinase C vs. Ensembl Mouse
Match: Prkcg (Protein kinase C gamma type [Source:UniProtKB/Swiss-Prot;Acc:P63318])

HSP 1 Score: 121.709 bits (304), Expect = 2.294e-29
Identity = 56/95 (58.95%), Postives = 78/95 (82.11%), Query Frame = 3
Query:  978 CDMNVHGKCEKNVPCLCGVDHTERRGRIHIIVRLERL-KLHVTVVESKNLVPMDPNGLADPYVKIKLTPSDDQSGKKFKTKTIRSSLNPVWNESF 1259
            C+MNVH +C ++VP LCGVDHTERRGR+ + +R     ++H+TV E++NL+PMDPNGL+DPYVK+KL P D ++  K KTKT++++LNPVWNE+F
Sbjct:  134 CEMNVHRRCVRSVPSLCGVDHTERRGRLQLEIRAPTSDEIHITVGEARNLIPMDPNGLSDPYVKLKLIP-DPRNLTKQKTKTVKATLNPVWNETF 227          
BLAST of Protein kinase C vs. UniProt/SwissProt
Match: sp|P17252|KPCA_HUMAN (Protein kinase C alpha type OS=Homo sapiens OX=9606 GN=PRKCA PE=1 SV=4)

HSP 1 Score: 132.109 bits (331), Expect = 5.050e-32
Identity = 63/95 (66.32%), Postives = 77/95 (81.05%), Query Frame = 3
Query:  978 CDMNVHGKCEKNVPCLCGVDHTERRGRIHIIVRLERLKLHVTVVESKNLVPMDPNGLADPYVKIKLTPSDDQSGKKFKTKTIRSSLNPVWNESFT 1262
            CDMNVH +C  NVP LCG+DHTE+RGRI++   +   KLHVTV ++KNL+PMDPNGL+DPYVK+KL P D ++  K KTKTIRS+LNP WNESFT
Sbjct:  135 CDMNVHKQCVINVPSLCGMDHTEKRGRIYLKAEVADEKLHVTVRDAKNLIPMDPNGLSDPYVKLKLIP-DPKNESKQKTKTIRSTLNPQWNESFT 228          
BLAST of Protein kinase C vs. UniProt/SwissProt
Match: sp|P05696|KPCA_RAT (Protein kinase C alpha type OS=Rattus norvegicus OX=10116 GN=Prkca PE=1 SV=3)

HSP 1 Score: 131.724 bits (330), Expect = 6.048e-32
Identity = 63/95 (66.32%), Postives = 77/95 (81.05%), Query Frame = 3
Query:  978 CDMNVHGKCEKNVPCLCGVDHTERRGRIHIIVRLERLKLHVTVVESKNLVPMDPNGLADPYVKIKLTPSDDQSGKKFKTKTIRSSLNPVWNESFT 1262
            CDMNVH +C  NVP LCG+DHTE+RGRI++   +   KLHVTV ++KNL+PMDPNGL+DPYVK+KL P D ++  K KTKTIRS+LNP WNESFT
Sbjct:  135 CDMNVHKQCVINVPSLCGMDHTEKRGRIYLKAEVTDEKLHVTVRDAKNLIPMDPNGLSDPYVKLKLIP-DPKNESKQKTKTIRSTLNPQWNESFT 228          
BLAST of Protein kinase C vs. UniProt/SwissProt
Match: sp|P10102|KPCA_RABIT (Protein kinase C alpha type OS=Oryctolagus cuniculus OX=9986 GN=PRKCA PE=2 SV=3)

HSP 1 Score: 131.724 bits (330), Expect = 6.778e-32
Identity = 63/95 (66.32%), Postives = 77/95 (81.05%), Query Frame = 3
Query:  978 CDMNVHGKCEKNVPCLCGVDHTERRGRIHIIVRLERLKLHVTVVESKNLVPMDPNGLADPYVKIKLTPSDDQSGKKFKTKTIRSSLNPVWNESFT 1262
            CDMNVH +C  NVP LCG+DHTE+RGRI++   +   KLHVTV ++KNL+PMDPNGL+DPYVK+KL P D ++  K KTKTIRS+LNP WNESFT
Sbjct:  135 CDMNVHKQCVINVPSLCGMDHTEKRGRIYLKAEVTDEKLHVTVRDAKNLIPMDPNGLSDPYVKLKLIP-DPKNESKQKTKTIRSTLNPQWNESFT 228          
BLAST of Protein kinase C vs. UniProt/SwissProt
Match: sp|P04409|KPCA_BOVIN (Protein kinase C alpha type OS=Bos taurus OX=9913 GN=PRKCA PE=1 SV=3)

HSP 1 Score: 129.413 bits (324), Expect = 3.363e-31
Identity = 62/95 (65.26%), Postives = 77/95 (81.05%), Query Frame = 3
Query:  978 CDMNVHGKCEKNVPCLCGVDHTERRGRIHIIVRLERLKLHVTVVESKNLVPMDPNGLADPYVKIKLTPSDDQSGKKFKTKTIRSSLNPVWNESFT 1262
            CDMNVH +C  NVP LCG+DHTE+RGRI++   +   KLHVTV ++KNL+PMDPNGL+DPYVK+KL P D ++  K KTKTIRS+LNP W+ESFT
Sbjct:  135 CDMNVHKQCVINVPSLCGMDHTEKRGRIYLKAEVTDEKLHVTVRDAKNLIPMDPNGLSDPYVKLKLIP-DPKNESKQKTKTIRSTLNPRWDESFT 228          
BLAST of Protein kinase C vs. UniProt/SwissProt
Match: sp|P20444|KPCA_MOUSE (Protein kinase C alpha type OS=Mus musculus OX=10090 GN=Prkca PE=1 SV=3)

HSP 1 Score: 128.642 bits (322), Expect = 6.901e-31
Identity = 62/95 (65.26%), Postives = 76/95 (80.00%), Query Frame = 3
Query:  978 CDMNVHGKCEKNVPCLCGVDHTERRGRIHIIVRLERLKLHVTVVESKNLVPMDPNGLADPYVKIKLTPSDDQSGKKFKTKTIRSSLNPVWNESFT 1262
            CDMNVH +C  N P LCG+DHTE+RGRI++   +   KLHVTV ++KNL+PMDPNGL+DPYVK+KL P D ++  K KTKTIRS+LNP WNESFT
Sbjct:  135 CDMNVHKQCVINDPSLCGMDHTEKRGRIYLKAEVTDEKLHVTVRDAKNLIPMDPNGLSDPYVKLKLIP-DPKNESKQKTKTIRSNLNPQWNESFT 228          
BLAST of Protein kinase C vs. TrEMBL
Match: W5L9B7 (Protein kinase C, gamma OS=Astyanax mexicanus OX=7994 PE=3 SV=2)

HSP 1 Score: 149.828 bits (377), Expect = 2.681e-35
Identity = 66/95 (69.47%), Postives = 80/95 (84.21%), Query Frame = 3
Query:  978 CDMNVHGKCEKNVPCLCGVDHTERRGRIHIIVRLERLKLHVTVVESKNLVPMDPNGLADPYVKIKLTPSDDQSGKKFKTKTIRSSLNPVWNESFT 1262
            CDMNVH +CE +VP LCG DHTE+RGRIH+ VR E+  ++VTV E++NL+PMDPNGL+DPYVK+KL P D +S  K KTKTIRS+LNPVWNESFT
Sbjct:  742 CDMNVHKRCESSVPSLCGHDHTEKRGRIHLTVRGEKEDIYVTVREARNLIPMDPNGLSDPYVKLKLIP-DPKSHSKQKTKTIRSTLNPVWNESFT 835          
BLAST of Protein kinase C vs. TrEMBL
Match: A0A0R3WKL0 (Uncharacterized protein OS=Hydatigena taeniaeformis OX=6205 GN=TTAC_LOCUS1255 PE=4 SV=1)

HSP 1 Score: 132.494 bits (332), Expect = 4.249e-34
Identity = 63/94 (67.02%), Postives = 71/94 (75.53%), Query Frame = 3
Query:  978 CDMNVHGKCEKNVPCLCGVDHTERRGRIHIIVRLERLKLHVTVVESKNLVPMDPNGLADPYVKIKLTPSDDQSGKKFKTKTIRSSLNPVWNESF 1259
            CDMNVH KC+  VP LCGVDHTERRGRIH+    +   L V ++ +KNL PMDPNGLADPYVKIKL P+DD    KFKTK IRS+LNP WNE F
Sbjct:    6 CDMNVHIKCKAMVPGLCGVDHTERRGRIHLQAHHKGDHLEVRILGAKNLTPMDPNGLADPYVKIKLNPADDNQKVKFKTKIIRSTLNPSWNEEF 99          
BLAST of Protein kinase C vs. TrEMBL
Match: A0A2U9AY36 (Guanylate cyclase OS=Scophthalmus maximus OX=52904 GN=SMAX5B_012177 PE=3 SV=1)

HSP 1 Score: 146.362 bits (368), Expect = 4.585e-34
Identity = 66/95 (69.47%), Postives = 79/95 (83.16%), Query Frame = 3
Query:  978 CDMNVHGKCEKNVPCLCGVDHTERRGRIHIIVRLERLKLHVTVVESKNLVPMDPNGLADPYVKIKLTPSDDQSGKKFKTKTIRSSLNPVWNESFT 1262
            CDMNVH +CE +VP LCG DHTE+RGRIH+ VR E+  + VTV E++NL+PMDPNGL+DPYVK+KL P D +S  K KTKTIRS+LNPVWNESFT
Sbjct: 1273 CDMNVHRRCETSVPSLCGQDHTEKRGRIHLTVRGEKEDVFVTVREARNLMPMDPNGLSDPYVKLKLIP-DPKSHSKQKTKTIRSTLNPVWNESFT 1366          
BLAST of Protein kinase C vs. TrEMBL
Match: A0A1I8HKC9 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 133.265 bits (334), Expect = 4.891e-34
Identity = 63/94 (67.02%), Postives = 73/94 (77.66%), Query Frame = 3
Query:  978 CDMNVHGKCEKNVPCLCGVDHTERRGRIHIIVRLERLKLHVTVVESKNLVPMDPNGLADPYVKIKLTPSDDQSGKKFKTKTIRSSLNPVWNESF 1259
            CDMNVH +CE+NVP LCG+DHTERRGRI + V L   +L + VVE KNL PMDPNGLADPYVK+KL P D  S K  KTK I+++LNPVWNE F
Sbjct:   38 CDMNVHERCERNVPGLCGIDHTERRGRIQLQVHLTDQRLRIEVVEGKNLAPMDPNGLADPYVKLKLVPDDSNSKK--KTKVIKATLNPVWNEKF 129          
BLAST of Protein kinase C vs. TrEMBL
Match: A0A3B4AE09 (Protein kinase C, gamma OS=Periophthalmus magnuspinnatus OX=409849 PE=4 SV=1)

HSP 1 Score: 137.117 bits (344), Expect = 1.735e-33
Identity = 65/95 (68.42%), Postives = 80/95 (84.21%), Query Frame = 3
Query:  978 CDMNVHGKCEKNVPCLCGVDHTERRGRIHIIVRLERLKLHVTVVESKNLVPMDPNGLADPYVKIKLTPSDDQSGKKFKTKTIRSSLNPVWNESFT 1262
            CDMNVH +CE +VP LCG DHTE+RGRIH+ +R E+  ++VTV E++NL+PMDPNGL+DPYVK+KL P D +S  K KTKTIRS+LNPVWNESFT
Sbjct:  123 CDMNVHRRCETSVPSLCGQDHTEKRGRIHLTIRGEKEDVYVTVREARNLMPMDPNGLSDPYVKLKLIP-DPKSHSKQKTKTIRSTLNPVWNESFT 216          
BLAST of Protein kinase C vs. Ensembl Cavefish
Match: prkcg (protein kinase C, gamma [Source:ZFIN;Acc:ZDB-GENE-090206-1])

HSP 1 Score: 149.828 bits (377), Expect = 1.015e-38
Identity = 66/95 (69.47%), Postives = 80/95 (84.21%), Query Frame = 3
Query:  978 CDMNVHGKCEKNVPCLCGVDHTERRGRIHIIVRLERLKLHVTVVESKNLVPMDPNGLADPYVKIKLTPSDDQSGKKFKTKTIRSSLNPVWNESFT 1262
            CDMNVH +CE +VP LCG DHTE+RGRIH+ VR E+  ++VTV E++NL+PMDPNGL+DPYVK+KL P D +S  K KTKTIRS+LNPVWNESFT
Sbjct:  742 CDMNVHKRCESSVPSLCGHDHTEKRGRIHLTVRGEKEDIYVTVREARNLIPMDPNGLSDPYVKLKLIP-DPKSHSKQKTKTIRSTLNPVWNESFT 835          
BLAST of Protein kinase C vs. Ensembl Cavefish
Match: prkcaa (protein kinase C, alpha, a [Source:ZFIN;Acc:ZDB-GENE-050208-100])

HSP 1 Score: 132.109 bits (331), Expect = 4.624e-33
Identity = 62/94 (65.96%), Postives = 73/94 (77.66%), Query Frame = 3
Query:  978 CDMNVHGKCEKNVPCLCGVDHTERRGRIHIIVRLERLKLHVTVVESKNLVPMDPNGLADPYVKIKLTPSDDQSGKKFKTKTIRSSLNPVWNESF 1259
            CDMNVH +C  NVP LCG DHTERRGRI + + +   +LHVTV E++NL+PMDPNGL+DPYVK+KL P      KK KT+TIRSSLNP WNESF
Sbjct:  108 CDMNVHKQCVLNVPSLCGTDHTERRGRIFLKIEVSGEELHVTVGEARNLIPMDPNGLSDPYVKLKLIPDPKNETKK-KTRTIRSSLNPTWNESF 200          
BLAST of Protein kinase C vs. Ensembl Cavefish
Match: prkcaa (protein kinase C, alpha, a [Source:ZFIN;Acc:ZDB-GENE-050208-100])

HSP 1 Score: 131.724 bits (330), Expect = 6.462e-33
Identity = 62/94 (65.96%), Postives = 73/94 (77.66%), Query Frame = 3
Query:  978 CDMNVHGKCEKNVPCLCGVDHTERRGRIHIIVRLERLKLHVTVVESKNLVPMDPNGLADPYVKIKLTPSDDQSGKKFKTKTIRSSLNPVWNESF 1259
            CDMNVH +C  NVP LCG DHTERRGRI + + +   +LHVTV E++NL+PMDPNGL+DPYVK+KL P      KK KT+TIRSSLNP WNESF
Sbjct:   91 CDMNVHKQCVLNVPSLCGTDHTERRGRIFLKIEVSGEELHVTVGEARNLIPMDPNGLSDPYVKLKLIPDPKNETKK-KTRTIRSSLNPTWNESF 183          
BLAST of Protein kinase C vs. Ensembl Cavefish
Match: prkcbb (protein kinase C beta type [Source:NCBI gene;Acc:103025973])

HSP 1 Score: 122.865 bits (307), Expect = 6.840e-30
Identity = 59/95 (62.11%), Postives = 71/95 (74.74%), Query Frame = 3
Query:  978 CDMNVHGKCEKNVPCLCGVDHTERRGRIHIIVRLERLKLHVTVVESKNLVPMDPNGLADPYVKIKLTPSDDQSGKKFKTKTIRSSLNPVWNESFT 1262
            C MN+H +C  NVP LCG DHTERRGRI I   ++   L V++ E+KNLVPMDPNGL+DPYVK+KL P D +S  K KTKTI+  LNP WNE+FT
Sbjct:  133 CMMNIHKRCVANVPSLCGTDHTERRGRIQITADIKNNALTVSIKEAKNLVPMDPNGLSDPYVKLKLIP-DPKSESKQKTKTIKCCLNPTWNETFT 226          
BLAST of Protein kinase C vs. Ensembl Cavefish
Match: prkcbb (protein kinase C beta type [Source:NCBI gene;Acc:103025973])

HSP 1 Score: 122.865 bits (307), Expect = 8.135e-30
Identity = 59/95 (62.11%), Postives = 71/95 (74.74%), Query Frame = 3
Query:  978 CDMNVHGKCEKNVPCLCGVDHTERRGRIHIIVRLERLKLHVTVVESKNLVPMDPNGLADPYVKIKLTPSDDQSGKKFKTKTIRSSLNPVWNESFT 1262
            C MN+H +C  NVP LCG DHTERRGRI I   ++   L V++ E+KNLVPMDPNGL+DPYVK+KL P D +S  K KTKTI+  LNP WNE+FT
Sbjct:  133 CMMNIHKRCVANVPSLCGTDHTERRGRIQITADIKNNALTVSIKEAKNLVPMDPNGLSDPYVKLKLIP-DPKSESKQKTKTIKCCLNPTWNETFT 226          
BLAST of Protein kinase C vs. Ensembl Sea Lamprey
Match: syt2a (synaptotagmin IIa [Source:ZFIN;Acc:ZDB-GENE-060503-315])

HSP 1 Score: 50.447 bits (119), Expect = 1.278e-7
Identity = 26/58 (44.83%), Postives = 37/58 (63.79%), Query Frame = 3
Query: 1089 KLHVTVVESKNLVPMDPNGLADPYVKIKLTPSDDQSGKKFKTKTIRSSLNPVWNESFT 1262
            +L V V+++  L  +D  G +DPYVK+ L P      KK++TK  R +LNPV+NESF 
Sbjct:   95 QLTVGVIQAAELPALDMGGTSDPYVKLFLMPD---KKKKYETKVHRKTLNPVFNESFV 149          
BLAST of Protein kinase C vs. Ensembl Sea Lamprey
Match: syt2a (synaptotagmin IIa [Source:ZFIN;Acc:ZDB-GENE-060503-315])

HSP 1 Score: 50.8322 bits (120), Expect = 1.489e-7
Identity = 26/58 (44.83%), Postives = 37/58 (63.79%), Query Frame = 3
Query: 1089 KLHVTVVESKNLVPMDPNGLADPYVKIKLTPSDDQSGKKFKTKTIRSSLNPVWNESFT 1262
            +L V V+++  L  +D  G +DPYVK+ L P      KK++TK  R +LNPV+NESF 
Sbjct:  112 QLTVGVIQAAELPALDMGGTSDPYVKLFLMPD---KKKKYETKVHRKTLNPVFNESFV 166          
BLAST of Protein kinase C vs. Ensembl Sea Lamprey
Match: SYT5 (synaptotagmin 5 [Source:HGNC Symbol;Acc:HGNC:11513])

HSP 1 Score: 50.0618 bits (118), Expect = 2.186e-7
Identity = 25/76 (32.89%), Postives = 44/76 (57.89%), Query Frame = 3
Query: 1035 DHTERRGRIHIIVRLERLKLHVTVVESKNLVPMDPNGLADPYVKIKLTPSDDQSGKKFKTKTIRSSLNPVWNESFT 1262
            ++T  R +  +   L+  +  V ++++ +L  MD  G++DPYV++ L P      KKF+T   R +LNP++ E FT
Sbjct:   76 ENTLGRLQFSLDYNLKTSQFTVGILQATDLAAMDIGGMSDPYVRVYLLP---HKKKKFETSVHRKTLNPIFEEKFT 148          
BLAST of Protein kinase C vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005675.1 (pep scaffold:Pmarinus_7.0:GL478818:76703:93830:1 gene:ENSPMAG00000005128.1 transcript:ENSPMAT00000005675.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 48.9062 bits (115), Expect = 1.336e-6
Identity = 23/58 (39.66%), Postives = 37/58 (63.79%), Query Frame = 3
Query: 1089 KLHVTVVESKNLVPMDPNGLADPYVKIKLTPSDDQS-GKKFKTKTIRSSLNPVWNESF 1259
            +LHV V+ +  L  MD NGL+DP+V + L P       K  +T+T  ++LNP+++E+F
Sbjct:  375 RLHVEVLNATGLPAMDSNGLSDPFVTLDLCPYHHFPLAKSARTQTQNNTLNPIFDETF 432          
BLAST of Protein kinase C vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004430.1 (pep scaffold:Pmarinus_7.0:GL476335:1496408:1550941:1 gene:ENSPMAG00000004026.1 transcript:ENSPMAT00000004430.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 48.1358 bits (113), Expect = 2.795e-6
Identity = 27/78 (34.62%), Postives = 42/78 (53.85%), Query Frame = 3
Query: 1053 GRIHIIVRLERLK--LHVTVVESKNLVPMDPNGLADPYVKIKLTPSDDQ--------SGKKFKTKTIRSSLNPVWNES 1256
            G I + +  +R    L + V++++ L P D NG +DP+VK+ L P   Q        S  K +TK I  +LNP WN++
Sbjct:  158 GEIQLQMSFDRHSGNLIIHVLQARGLAPRDNNGFSDPFVKVYLLPGRGQVMVVQNASSENKRRTKYIHKTLNPEWNQT 235          
BLAST of Protein kinase C vs. Ensembl Nematostella
Match: EDO44925 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RUL8])

HSP 1 Score: 117.857 bits (294), Expect = 2.276e-29
Identity = 58/94 (61.70%), Postives = 70/94 (74.47%), Query Frame = 3
Query:  978 CDMNVHGKCEKNVPCLCGVDHTERRGRIHIIVRLERLKLHVTVVESKNLVPMDPNGLADPYVKIKLTPSDDQSGKKFKTKTIRSSLNPVWNESF 1259
            CDMNVH KCEK VP LCG DHTERRGRIH       LK+   + E++NL+PMDPNGL+DPYVK+KL P  D + KK KTK  + SL+PV+NE+F
Sbjct:   36 CDMNVHKKCEKAVPKLCGADHTERRGRIH-------LKISYELREARNLMPMDPNGLSDPYVKVKLLPDPDNTSKK-KTKIFKESLSPVFNETF 121          
BLAST of Protein kinase C vs. Ensembl Nematostella
Match: EDO41933 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S352])

HSP 1 Score: 53.9138 bits (128), Expect = 4.005e-8
Identity = 33/92 (35.87%), Postives = 51/92 (55.43%), Query Frame = 3
Query:  996 GKCEKNVPCLC-GVDHTERRGRIHIIVRLERL--KLHVTVVESKNLVPMDPNGLADPYVKIKLTPSDDQSGKKFKTKTIRSSLNPVWNESFT 1262
            G C+     LC G+      G +   +R ++L  +L V + ++K L PMD  G +DPYVK+ L P   +S  K ++ T   +LNPV+NE+ T
Sbjct:    6 GLCQSKTAHLCLGL------GLLEFTLRYQKLDSRLDVVLHDAKGLKPMDHGGTSDPYVKLHLLPGASKS-NKLRSHTKYKTLNPVFNETLT 90          

HSP 2 Score: 51.6026 bits (122), Expect = 2.313e-7
Identity = 30/71 (42.25%), Postives = 40/71 (56.34%), Query Frame = 3
Query: 1053 GRIHIIVRL--ERLKLHVTVVESKNLVPMDPNGLADPYVKIKLTPSDDQSGKKFKTKTIRSSLNPVWNESF 1259
            GRI + ++   +R  L VTV+    L  MD NG +DPYVK  L P D Q   K +T   + +LNP +NE F
Sbjct:  155 GRIQLALKYNTQRGMLFVTVMRCSGLASMDANGYSDPYVKCYLKP-DPQKKSKRRTNIRKKTLNPEFNEEF 224          
BLAST of Protein kinase C vs. Ensembl Nematostella
Match: EDO49802 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RFY4])

HSP 1 Score: 52.373 bits (124), Expect = 1.467e-7
Identity = 32/84 (38.10%), Postives = 51/84 (60.71%), Query Frame = 3
Query: 1017 PCLCGVDHTERRGRIHIIVRL---ERLKLHVTVVESKNLVPMDPNGLADPYVKIKLTPSDDQSGKKFKTKTIRSSLNPVWNESF 1259
            P +   D  + +G I + ++    E+L L V V+ +++LVP D NG +DPYV ++L P   + G K KT+  + +LNPV+NE F
Sbjct:   19 PTVTQADSGDIKGDIEMSLKYNHREQLLL-VKVIRARDLVPRDLNGKSDPYVVLELVPDRLEEGTK-KTRFKQKTLNPVFNEIF 100          
BLAST of Protein kinase C vs. Ensembl Nematostella
Match: EDO29765 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T2P9])

HSP 1 Score: 50.447 bits (119), Expect = 6.164e-7
Identity = 25/55 (45.45%), Postives = 38/55 (69.09%), Query Frame = 3
Query: 1089 KLHVTVVESKNLVPMDPNGLADPYVKIKLTPSDDQSGK-KFKTKTIRSSLNPVWN 1250
            +LHV ++E+KNL   D +G++DP+ KI L P  D+ GK + KT  I+ +LNP W+
Sbjct:  180 ELHVHIMEAKNLPGKDADGMSDPFCKITLLP--DKKGKTRHKTAIIKRTLNPSWD 232          
BLAST of Protein kinase C vs. Ensembl Nematostella
Match: EDO45740 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RS41])

HSP 1 Score: 51.2174 bits (121), Expect = 6.343e-7
Identity = 20/56 (35.71%), Postives = 35/56 (62.50%), Query Frame = 3
Query: 1092 LHVTVVESKNLVPMDPNGLADPYVKIKLTPSDDQSGKKFKTKTIRSSLNPVWNESF 1259
            + + +VE K ++PMD +G +DPY + +L        +K+K+K  + +LNP W+E F
Sbjct:  159 VSIILVEGKKMIPMDDSGFSDPYCRFRL------GNEKYKSKACKETLNPQWSEQF 208          
BLAST of Protein kinase C vs. Ensembl Medaka
Match: prkcg (protein kinase C alpha type [Source:NCBI gene;Acc:101164921])

HSP 1 Score: 137.502 bits (345), Expect = 9.304e-35
Identity = 64/95 (67.37%), Postives = 80/95 (84.21%), Query Frame = 3
Query:  978 CDMNVHGKCEKNVPCLCGVDHTERRGRIHIIVRLERLKLHVTVVESKNLVPMDPNGLADPYVKIKLTPSDDQSGKKFKTKTIRSSLNPVWNESFT 1262
            CDMNVH +CE +VP LCG DHTE+RGRIH+ +R ++  ++VTV E++NL+PMDPNGL+DPYVK+KL P D +S  K KTKTIRS+LNPVWNESFT
Sbjct:  158 CDMNVHRRCETSVPSLCGQDHTEKRGRIHLTIRGDKEDVYVTVREARNLMPMDPNGLSDPYVKLKLIP-DPKSHSKQKTKTIRSTLNPVWNESFT 251          
BLAST of Protein kinase C vs. Ensembl Medaka
Match: prkcab (protein kinase C alpha type [Source:NCBI gene;Acc:101159746])

HSP 1 Score: 132.109 bits (331), Expect = 5.699e-33
Identity = 62/95 (65.26%), Postives = 77/95 (81.05%), Query Frame = 3
Query:  978 CDMNVHGKCEKNVPCLCGVDHTERRGRIHIIVRLERLKLHVTVVESKNLVPMDPNGLADPYVKIKLTPSDDQSGKKFKTKTIRSSLNPVWNESFT 1262
            CDMNVH +C  NVP LCG+DHTERRGR+ + + +   KLH+TV E++NL+PMDPNGL+DPYVK+KL P D ++  K KT+TIRSSLNP WNESFT
Sbjct:  133 CDMNVHKQCVVNVPSLCGMDHTERRGRVFLKIEVSGDKLHITVGEARNLIPMDPNGLSDPYVKLKLIP-DPKNETKQKTRTIRSSLNPCWNESFT 226          
BLAST of Protein kinase C vs. Ensembl Medaka
Match: prkcg (protein kinase C alpha type [Source:NCBI gene;Acc:101164921])

HSP 1 Score: 128.642 bits (322), Expect = 8.628e-32
Identity = 61/98 (62.24%), Postives = 78/98 (79.59%), Query Frame = 3
Query:  978 CDMNVHGKCEKNVPCLCGVDHTERRGRIHIIVRLERLKLHVTVV---ESKNLVPMDPNGLADPYVKIKLTPSDDQSGKKFKTKTIRSSLNPVWNESFT 1262
            CDMNVH +CE +VP LCG DHTE+RGRIH+ +R ++  + + +    E++NL+PMDPNGL+DPYVK+KL P D +S  K KTKTIRS+LNPVWNESFT
Sbjct:  130 CDMNVHRRCETSVPSLCGQDHTEKRGRIHLTIRGDKEDIFIYLFFLREARNLMPMDPNGLSDPYVKLKLIP-DPKSHSKQKTKTIRSTLNPVWNESFT 226          
BLAST of Protein kinase C vs. Ensembl Medaka
Match: prkcba (protein kinase C beta type [Source:NCBI gene;Acc:101161464])

HSP 1 Score: 122.865 bits (307), Expect = 7.428e-30
Identity = 58/95 (61.05%), Postives = 71/95 (74.74%), Query Frame = 3
Query:  978 CDMNVHGKCEKNVPCLCGVDHTERRGRIHIIVRLERLKLHVTVVESKNLVPMDPNGLADPYVKIKLTPSDDQSGKKFKTKTIRSSLNPVWNESFT 1262
            C MN+H +C  NVP LCG DHTERRGR+ I  ++ +  L VT+ E +NLVPMDPNGL+DPYVK+KL P D +S  K KTKTI+  LNP WNE+FT
Sbjct:  132 CMMNIHKRCVANVPSLCGTDHTERRGRLQITAQITQGTLTVTIKEGRNLVPMDPNGLSDPYVKLKLIP-DPKSESKQKTKTIKCCLNPTWNETFT 225          
BLAST of Protein kinase C vs. Ensembl Medaka
Match: prkcba (protein kinase C beta type [Source:NCBI gene;Acc:101161464])

HSP 1 Score: 122.479 bits (306), Expect = 8.471e-30
Identity = 58/95 (61.05%), Postives = 71/95 (74.74%), Query Frame = 3
Query:  978 CDMNVHGKCEKNVPCLCGVDHTERRGRIHIIVRLERLKLHVTVVESKNLVPMDPNGLADPYVKIKLTPSDDQSGKKFKTKTIRSSLNPVWNESFT 1262
            C MN+H +C  NVP LCG DHTERRGR+ I  ++ +  L VT+ E +NLVPMDPNGL+DPYVK+KL P D +S  K KTKTI+  LNP WNE+FT
Sbjct:  132 CMMNIHKRCVANVPSLCGTDHTERRGRLQITAQITQGTLTVTIKEGRNLVPMDPNGLSDPYVKLKLIP-DPKSESKQKTKTIKCCLNPTWNETFT 225          
BLAST of Protein kinase C vs. Planmine SMEST
Match: SMESG000071570.1 (SMESG000071570.1)

HSP 1 Score: 201.445 bits (511), Expect = 6.252e-58
Identity = 95/96 (98.96%), Postives = 96/96 (100.00%), Query Frame = 3
Query:  975 DCDMNVHGKCEKNVPCLCGVDHTERRGRIHIIVRLERLKLHVTVVESKNLVPMDPNGLADPYVKIKLTPSDDQSGKKFKTKTIRSSLNPVWNESFT 1262
            +CDMNVHGKCEKNVPCLCGVDHTERRGRIHIIVRLERLKLHVTVVESKNLVPMDPNGLADPYVKIKLTPSDDQSGKKFKTKTIRSSLNPVWNESFT
Sbjct:  129 NCDMNVHGKCEKNVPCLCGVDHTERRGRIHIIVRLERLKLHVTVVESKNLVPMDPNGLADPYVKIKLTPSDDQSGKKFKTKTIRSSLNPVWNESFT 224          
BLAST of Protein kinase C vs. Planmine SMEST
Match: SMESG000039865.1 (SMESG000039865.1)

HSP 1 Score: 64.3142 bits (155), Expect = 7.224e-11
Identity = 31/43 (72.09%), Postives = 37/43 (86.05%), Query Frame = 3
Query: 1131 MDPNGLADPYVKIKLTPSDDQSGKKFKTKTIRSSLNPVWNESF 1259
            MDPNGLADPYVKIK+ P +DQS K+ KTKTI+++LNP WNE F
Sbjct:    1 MDPNGLADPYVKIKIVP-EDQSRKQ-KTKTIKATLNPTWNEKF 41          
BLAST of Protein kinase C vs. Planmine SMEST
Match: SMESG000039854.1 (SMESG000039854.1)

HSP 1 Score: 57.7658 bits (138), Expect = 1.051e-9
Identity = 26/41 (63.41%), Postives = 32/41 (78.05%), Query Frame = 3
Query:  978 CDMNVHGKCEKNVPCLCGVDHTERRGRIHIIVRLERLKLHV 1100
            CD NVH KCEKNVP LCG+DHTERRGRI++ +     K++V
Sbjct:  131 CDTNVHKKCEKNVPKLCGMDHTERRGRIYLKINYNNGKMNV 171          
BLAST of Protein kinase C vs. Planmine SMEST
Match: SMESG000053142.1 (SMESG000053142.1)

HSP 1 Score: 58.151 bits (139), Expect = 8.206e-9
Identity = 28/58 (48.28%), Postives = 41/58 (70.69%), Query Frame = 3
Query: 1092 LHVTVVESKNLVPMDPNGLADPYVKIKLTPSD--DQSGKKFKTKTIRSSLNPVWNESF 1259
            L V ++ + +L+P+D NGL+DP+V I+L PS    QS K  KTK +++SLNP +NE F
Sbjct: 1039 LIVEIINANDLIPLDSNGLSDPFVIIELAPSHYFGQSFKPLKTKIVKNSLNPEFNEVF 1096          
BLAST of Protein kinase C vs. Planmine SMEST
Match: SMESG000053142.1 (SMESG000053142.1)

HSP 1 Score: 58.151 bits (139), Expect = 8.499e-9
Identity = 28/58 (48.28%), Postives = 41/58 (70.69%), Query Frame = 3
Query: 1092 LHVTVVESKNLVPMDPNGLADPYVKIKLTPSD--DQSGKKFKTKTIRSSLNPVWNESF 1259
            L V ++ + +L+P+D NGL+DP+V I+L PS    QS K  KTK +++SLNP +NE F
Sbjct: 1040 LIVEIINANDLIPLDSNGLSDPFVIIELAPSHYFGQSFKPLKTKIVKNSLNPEFNEVF 1097          
The following BLAST results are available for this feature:
BLAST of Protein kinase C vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
PRKCA3.444e-3466.32protein kinase C alpha [Source:HGNC Symbol;Acc:HGN... [more]
PRKCG3.512e-3358.95protein kinase C gamma [Source:HGNC Symbol;Acc:HGN... [more]
PRKCA1.052e-3266.32protein kinase C alpha [Source:HGNC Symbol;Acc:HGN... [more]
PRKCB2.399e-2964.89protein kinase C beta [Source:HGNC Symbol;Acc:HGNC... [more]
PRKCB2.673e-2964.89protein kinase C beta [Source:HGNC Symbol;Acc:HGNC... [more]
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BLAST of Protein kinase C vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pkc-22.791e-3057.89Protein kinase C-like 2 [Source:UniProtKB/Swiss-P... [more]
pkc-23.278e-3057.89Protein kinase C-like 2 [Source:UniProtKB/Swiss-P... [more]
pkc-23.352e-3057.89Protein kinase C-like 2 [Source:UniProtKB/Swiss-P... [more]
pkc-23.542e-3057.89Protein kinase C-like 2 [Source:UniProtKB/Swiss-P... [more]
snt-25.882e-1144.59Synaptotagmin 2 [Source:UniProtKB/Swiss-Prot;Acc:... [more]
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BLAST of Protein kinase C vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Pkc53E2.270e-3160.00gene:FBgn0003091 transcript:FBtr0331960[more]
Pkc53E2.270e-3160.00gene:FBgn0003091 transcript:FBtr0087049[more]
Pkc53E2.333e-3160.00gene:FBgn0003091 transcript:FBtr0087048[more]
Pkc53E2.462e-3160.00gene:FBgn0003091 transcript:FBtr0112819[more]
Pkc53E2.462e-3160.00gene:FBgn0003091 transcript:FBtr0305070[more]
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BLAST of Protein kinase C vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
prkcg6.114e-3466.32protein kinase C, gamma [Source:ZFIN;Acc:ZDB-GENE-... [more]
prkcaa4.335e-3366.32protein kinase C, alpha, a [Source:ZFIN;Acc:ZDB-GE... [more]
prkcaa4.806e-3366.32protein kinase C, alpha, a [Source:ZFIN;Acc:ZDB-GE... [more]
prkcab8.814e-3365.96protein kinase C, alpha, b [Source:ZFIN;Acc:ZDB-GE... [more]
prkcab1.001e-3265.96protein kinase C, alpha, b [Source:ZFIN;Acc:ZDB-GE... [more]
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BLAST of Protein kinase C vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
prkcb1.484e-3065.96protein kinase C beta [Source:NCBI gene;Acc:100038... [more]
prkcb1.723e-3065.96protein kinase C beta [Source:NCBI gene;Acc:100038... [more]
prkcb1.783e-3065.96protein kinase C beta [Source:NCBI gene;Acc:100038... [more]
prkcb1.887e-3065.96protein kinase C beta [Source:NCBI gene;Acc:100038... [more]
prkcb1.964e-3065.96protein kinase C beta [Source:NCBI gene;Acc:100038... [more]
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BLAST of Protein kinase C vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Prkca8.729e-3366.32protein kinase C, alpha [Source:MGI Symbol;Acc:MGI... [more]
Prkcb9.470e-3064.89protein kinase C, beta [Source:MGI Symbol;Acc:MGI:... [more]
Prkcb1.127e-2964.89protein kinase C, beta [Source:MGI Symbol;Acc:MGI:... [more]
Prkcb1.127e-2964.89protein kinase C, beta [Source:MGI Symbol;Acc:MGI:... [more]
Prkcg2.294e-2958.95Protein kinase C gamma type [Source:UniProtKB/Swi... [more]
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BLAST of Protein kinase C vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P17252|KPCA_HUMAN5.050e-3266.32Protein kinase C alpha type OS=Homo sapiens OX=960... [more]
sp|P05696|KPCA_RAT6.048e-3266.32Protein kinase C alpha type OS=Rattus norvegicus O... [more]
sp|P10102|KPCA_RABIT6.778e-3266.32Protein kinase C alpha type OS=Oryctolagus cunicul... [more]
sp|P04409|KPCA_BOVIN3.363e-3165.26Protein kinase C alpha type OS=Bos taurus OX=9913 ... [more]
sp|P20444|KPCA_MOUSE6.901e-3165.26Protein kinase C alpha type OS=Mus musculus OX=100... [more]
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BLAST of Protein kinase C vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
W5L9B72.681e-3569.47Protein kinase C, gamma OS=Astyanax mexicanus OX=7... [more]
A0A0R3WKL04.249e-3467.02Uncharacterized protein OS=Hydatigena taeniaeformi... [more]
A0A2U9AY364.585e-3469.47Guanylate cyclase OS=Scophthalmus maximus OX=52904... [more]
A0A1I8HKC94.891e-3467.02Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A3B4AE091.735e-3368.42Protein kinase C, gamma OS=Periophthalmus magnuspi... [more]
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BLAST of Protein kinase C vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
prkcg1.015e-3869.47protein kinase C, gamma [Source:ZFIN;Acc:ZDB-GENE-... [more]
prkcaa4.624e-3365.96protein kinase C, alpha, a [Source:ZFIN;Acc:ZDB-GE... [more]
prkcaa6.462e-3365.96protein kinase C, alpha, a [Source:ZFIN;Acc:ZDB-GE... [more]
prkcbb6.840e-3062.11protein kinase C beta type [Source:NCBI gene;Acc:1... [more]
prkcbb8.135e-3062.11protein kinase C beta type [Source:NCBI gene;Acc:1... [more]
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BLAST of Protein kinase C vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
syt2a1.278e-744.83synaptotagmin IIa [Source:ZFIN;Acc:ZDB-GENE-060503... [more]
syt2a1.489e-744.83synaptotagmin IIa [Source:ZFIN;Acc:ZDB-GENE-060503... [more]
SYT52.186e-732.89synaptotagmin 5 [Source:HGNC Symbol;Acc:HGNC:11513... [more]
ENSPMAT00000005675.11.336e-639.66pep scaffold:Pmarinus_7.0:GL478818:76703:93830:1 g... [more]
ENSPMAT00000004430.12.795e-634.62pep scaffold:Pmarinus_7.0:GL476335:1496408:1550941... [more]
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BLAST of Protein kinase C vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Protein kinase C vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO449252.276e-2961.70Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO419334.005e-835.87Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO498021.467e-738.10Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO297656.164e-745.45Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO457406.343e-735.71Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Protein kinase C vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
prkcg9.304e-3567.37protein kinase C alpha type [Source:NCBI gene;Acc:... [more]
prkcab5.699e-3365.26protein kinase C alpha type [Source:NCBI gene;Acc:... [more]
prkcg8.628e-3262.24protein kinase C alpha type [Source:NCBI gene;Acc:... [more]
prkcba7.428e-3061.05protein kinase C beta type [Source:NCBI gene;Acc:1... [more]
prkcba8.471e-3061.05protein kinase C beta type [Source:NCBI gene;Acc:1... [more]
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BLAST of Protein kinase C vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000071570.16.252e-5898.96SMESG000071570.1[more]
SMESG000039865.17.224e-1172.09SMESG000039865.1[more]
SMESG000039854.11.051e-963.41SMESG000039854.1[more]
SMESG000053142.18.206e-948.28SMESG000053142.1[more]
SMESG000053142.18.499e-948.28SMESG000053142.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30020212 ID=SMED30020212|Name=Protein kinase C|organism=Schmidtea mediterranea sexual|type=transcript|length=1264bp
CAAACCCTTCAGTCCAAAGATGTTGCTCACAAATCTATCCGACAATATGA
AATGTTGCACTGTGTAGCACAGTGAAATGTTATTTAATCAATAAATATTA
TCGAAATCGAAATTGAGATTTAATAAGTTGACCGATTCCAACAGTTGATA
TCAAATGGAAAATAAACGGTTTCCTATTAAAACAATGTTGATTTAGTGAT
CAGCGCGTCGCTGTGATCTAAATTCCGTAGATTTAAACAAACAATTATTC
ATCCAGTTTCAATGGATTAATTAGTGAATTGTGCTGAGATTTTAGGCCGA
TTTTTTATGGCAATATAAACCATGTTTTTTCAATGTCTAATTTTTATGTC
TCTATTATGCACCCGAATAATTTCTGTATTGTTTTTTATTATAGGTTTTG
CCAATTAATTTCCATCGCTGTTTTCGACTGGAAACCTTTTATGGAATTTT
ATCTCAAAATTATCATTAATTTTCTTCTATAAACATTACAAAAGCTGCAA
ACGAATGTATCAATTTGTATGAATATTTTAATCGGTTTTTGGTTACTGTT
AATTATTACGCTTTAATTATATGTTCGAGCTGGGATGAGATCTACAAATA
AATGTGAAAGATTTCCTTGAGAAAGCCTTCAACGGTTTTGTGGAAGGTAA
TGATATAGTTTATGTTCTTTTCAAATAGTTTCCTTTCATCATGAGCGATA
TAAGGAGAACCATTTCCAAGTAAACGGCCTTGATCGTTACCAGAAATAAA
AATACATATAATAAAGTATGAATATAATAAAACAATTCAAAATCACAGGT
TGAAATTATTTATTCAGCGTATTGACTCACAAAAAATAATTATTACTTTT
ACTCTTCAGATGTTTTTCTTTTCATCTCATAAAAACAACAAAAATAATTA
GAATTTTAAAGATTAAAACAAAACCAAAACATCTATGAGGCATTTTGATG
ATATTCTTATTTATTTTTCATTAAGACTGTGATATGAATGTCCACGGCAA
ATGCGAGAAGAACGTTCCTTGTCTTTGTGGAGTCGACCATACCGAGAGGC
GAGGCCGTATTCACATCATCGTGCGGTTAGAGCGTTTGAAACTTCATGTG
ACAGTTGTTGAAAGTAAAAATCTAGTGCCAATGGATCCAAATGGTCTCGC
TGATCCCTATGTTAAAATTAAGCTGACGCCATCAGATGATCAATCTGGGA
AAAAATTCAAAACTAAAACTATTCGGTCCTCGTTGAATCCAGTTTGGAAT
GAATCCTTTACTAT
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0004698calcium-dependent protein kinase C activity
GO:0005515protein binding
GO:0000166nucleotide binding
GO:0004672protein kinase activity
GO:0004674protein serine/threonine kinase activity
GO:0004697protein kinase C activity
GO:0005524ATP binding
GO:0008270zinc ion binding
GO:0016301kinase activity
GO:0016740transferase activity
GO:0046872metal ion binding
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
PLANA:0000101muscle cell
PLANA:0002056medial muscle cell
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR035892C2_domain_sf
IPR000008C2_dom
Vocabulary: biological process
TermDefinition
GO:0001881receptor recycling
GO:0006468protein phosphorylation
GO:0016310phosphorylation
GO:0035556intracellular signal transduction
GO:0060074synapse maturation
Vocabulary: cellular component
TermDefinition
GO:0005622intracellular
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000008C2 domainPRINTSPR00360C2DOMAINcoord: 82..93
score: 48.67
coord: 52..64
score: 56.98
IPR000008C2 domainPFAMPF00168C2coord: 36..93
e-value: 3.3E-16
score: 59.5
IPR000008C2 domainPROSITEPS50004C2coord: 36..93
score: 15.429
IPR035892C2 domain superfamilyGENE3DG3DSA:2.60.40.150coord: 20..93
e-value: 2.9E-22
score: 80.8
NoneNo IPR availablePANTHERPTHR24356:SF193PROTEIN KINASE C ALPHA TYPEcoord: 1..93
NoneNo IPR availablePANTHERPTHR24356SERINE/THREONINE-PROTEIN KINASEcoord: 1..93
NoneNo IPR availableSUPERFAMILYSSF49562C2 domain (Calcium/lipid-binding domain, CaLB)coord: 20..93