Kunitz-type protease inhibitor

Overview


Name	Kunitz-type protease inhibitor
Smed ID	SMED30020210
Length (bp)	313

Neoblast Clusters

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Kunitz-type protease inhibitor (SMED30020210) t-SNE clustered cells

Violin plots show distribution of expression levels for Kunitz-type protease inhibitor (SMED30020210) in cells (dots) of each of the 12 neoblast clusters.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30020210

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 5

Expressed In	Reference Transcript	Published Transcript	Transcriptome	Publication
prepharyngeal region	SMED30020210	SmedASXL_015573	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
pigment cell	SMED30020210	SmedASXL_015573	SmedAsxl_ww_GCZZ01	PMID:29158443 He et al., 2017
gut	SMED30020210	dd_Smed_v4_41_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
tail region	SMED30020210	dd_Smed_v6_41_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
goblet cell	SMED30020210	dd_Smed_v6_41_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018

Note: Hover over icons to view figure legend

Homology

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BLAST of Kunitz-type protease inhibitor vs. Ensembl Human
Match: TFPI (tissue factor pathway inhibitor [Source:HGNC Symbol;Acc:HGNC:11760])

HSP 1 Score: 63.929 bits (154), Expect = 5.288e-13
Identity = 29/53 (54.72%), Postives = 37/53 (69.81%), Query Frame = 1

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 297
            C L ++ G+CRGY  RYF+N +T +CE+F YGGC GN NNF T  EC+  CE 
Sbjct:  125 CFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNICED 177

HSP 2 Score: 51.9878 bits (123), Expect = 1.366e-8
Identity = 23/51 (45.10%), Postives = 33/51 (64.71%), Query Frame = 1

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
            C+   + G C+    R+FFN  T +CE+FIYGGC+GN+N F +  EC+  C
Sbjct:   54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMC 104

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Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 297
            C L ++ G+CRGY  RYF+N +T +CE+F YGGC GN NNF T  EC+  CE 
Sbjct:  125 CFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNICED 177

HSP 2 Score: 51.9878 bits (123), Expect = 1.366e-8
Identity = 23/51 (45.10%), Postives = 33/51 (64.71%), Query Frame = 1

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
            C+   + G C+    R+FFN  T +CE+FIYGGC+GN+N F +  EC+  C
Sbjct:   54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMC 104

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Human
Match: TFPI (tissue factor pathway inhibitor [Source:HGNC Symbol;Acc:HGNC:11760])

HSP 1 Score: 63.1586 bits (152), Expect = 7.146e-13
Identity = 29/53 (54.72%), Postives = 37/53 (69.81%), Query Frame = 1

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 297
            C L ++ G+CRGY  RYF+N +T +CE+F YGGC GN NNF T  EC+  CE 
Sbjct:  112 CFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNICED 164

HSP 2 Score: 51.2174 bits (121), Expect = 1.736e-8
Identity = 23/51 (45.10%), Postives = 33/51 (64.71%), Query Frame = 1

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
            C+   + G C+    R+FFN  T +CE+FIYGGC+GN+N F +  EC+  C
Sbjct:   54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMC 104

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Human
Match: TFPI (tissue factor pathway inhibitor [Source:HGNC Symbol;Acc:HGNC:11760])

HSP 1 Score: 63.1586 bits (152), Expect = 1.610e-12
Identity = 29/53 (54.72%), Postives = 37/53 (69.81%), Query Frame = 1

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 297
            C L ++ G+CRGY  RYF+N +T +CE+F YGGC GN NNF T  EC+  CE 
Sbjct:  125 CFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNICED 177

HSP 2 Score: 51.2174 bits (121), Expect = 2.928e-8
Identity = 23/53 (43.40%), Postives = 34/53 (64.15%), Query Frame = 1

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 297
            C+   + G C+    R+FFN  T +CE+FIYGGC+GN+N F +  EC+  C +
Sbjct:   54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTR 106

HSP 3 Score: 49.2914 bits (116), Expect = 1.351e-7
Identity = 23/53 (43.40%), Postives = 31/53 (58.49%), Query Frame = 1

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 297
            C  P + GLCR    R+++N   GKC  F Y GC GN+NNF +  EC   C++
Sbjct:  217 CLTPADRGLCRANENRFYYNSVIGKCRPFKYSGCGGNENNFTSKQECLRACKK 269

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Human
Match: TFPI (tissue factor pathway inhibitor [Source:HGNC Symbol;Acc:HGNC:11760])

HSP 1 Score: 63.1586 bits (152), Expect = 1.610e-12
Identity = 29/53 (54.72%), Postives = 37/53 (69.81%), Query Frame = 1

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 297
            C L ++ G+CRGY  RYF+N +T +CE+F YGGC GN NNF T  EC+  CE 
Sbjct:  125 CFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNICED 177

HSP 2 Score: 51.2174 bits (121), Expect = 2.928e-8
Identity = 23/53 (43.40%), Postives = 34/53 (64.15%), Query Frame = 1

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 297
            C+   + G C+    R+FFN  T +CE+FIYGGC+GN+N F +  EC+  C +
Sbjct:   54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTR 106

HSP 3 Score: 49.2914 bits (116), Expect = 1.351e-7
Identity = 23/53 (43.40%), Postives = 31/53 (58.49%), Query Frame = 1

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 297
            C  P + GLCR    R+++N   GKC  F Y GC GN+NNF +  EC   C++
Sbjct:  217 CLTPADRGLCRANENRFYYNSVIGKCRPFKYSGCGGNENNFTSKQECLRACKK 269

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BLAST of Kunitz-type protease inhibitor vs. Ensembl Celegans
Match: mlt-11 (pep chromosome:WBcel235:V:20667209:20678513:1 gene:WBGene00012186.1 transcript:W01F3.3c.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:mlt-11)

HSP 1 Score: 65.4698 bits (158), Expect = 1.381e-13
Identity = 29/74 (39.19%), Postives = 42/74 (56.76%), Query Frame = 1

Query:  100 AVAIHLGDCKEPE----------CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
            A  + LG   +P           C++P + G+C  Y PR+FFN +TG+CE+F YG C GN+NNF+    C  +C
Sbjct: 2025 ASVVPLGTTPQPHFEPKFDGRVVCAMPPDAGVCTNYTPRWFFNSQTGQCEQFAYGSCGGNENNFFDRNTCERKC 2098

HSP 2 Score: 56.9954 bits (136), Expect = 1.105e-10
Identity = 26/53 (49.06%), Postives = 34/53 (64.15%), Query Frame = 1

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 297
            C  P++ G CRG F R+FF++E   C+ F Y GCQGN NNF +  EC A C +
Sbjct:  608 CLHPRDSGNCRGQFVRWFFDDEKKNCDVFTYTGCQGNGNNFASKEECMAICHK 660

HSP 3 Score: 55.0694 bits (131), Expect = 5.506e-10
Identity = 25/63 (39.68%), Postives = 37/63 (58.73%), Query Frame = 1

Query:  103 VAIHLGDCKEPECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
            V +     +   CSLPKE G C  Y  R++FN +  +C+ F +GGC+GN+NNF    +C + C
Sbjct:  398 VGLQTSGARATRCSLPKERGPCDKYELRFYFNADLNECKYFFWGGCEGNQNNFERVEDCESAC 460

HSP 4 Score: 54.299 bits (129), Expect = 1.099e-9
Identity = 25/60 (41.67%), Postives = 35/60 (58.33%), Query Frame = 1

Query:  112 HLGDCKEPECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
            +L    E +C  P E G C+ +  R++FN + G C  F YGGC GN+N+F+T  EC   C
Sbjct:  945 NLAAQIEEKCLQPVEPGPCKNFADRWYFNVDDGTCHPFKYGGCAGNRNHFFTQKECEVHC 1004

HSP 5 Score: 53.1434 bits (126), Expect = 2.236e-9
Identity = 26/51 (50.98%), Postives = 32/51 (62.75%), Query Frame = 1

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
             SLP   G C G F RYF+NE++ KCE+F Y GC GN NN+ +   C  RC
Sbjct:  297 VSLP---GPCHGSFQRYFYNEDSQKCEQFTYSGCGGNGNNYESREACEDRC 344

HSP 6 Score: 50.0618 bits (118), Expect = 3.124e-8
Identity = 24/51 (47.06%), Postives = 28/51 (54.90%), Query Frame = 1

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
            C    EVG C G F R+ F++    C  F YGGC GN NNF T  EC  +C
Sbjct:  737 CEADIEVGECAGVFSRFAFDKSINACRSFTYGGCGGNANNFATLQECTNKC 787

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Celegans
Match: mlt-11 (pep chromosome:WBcel235:V:20667211:20678513:1 gene:WBGene00012186.1 transcript:W01F3.3b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:mlt-11)

HSP 1 Score: 65.0846 bits (157), Expect = 1.437e-13
Identity = 29/74 (39.19%), Postives = 42/74 (56.76%), Query Frame = 1

Query:  100 AVAIHLGDCKEPE----------CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
            A  + LG   +P           C++P + G+C  Y PR+FFN +TG+CE+F YG C GN+NNF+    C  +C
Sbjct: 2154 ASVVPLGTTPQPHFEPKFDGRVVCAMPPDAGVCTNYTPRWFFNSQTGQCEQFAYGSCGGNENNFFDRNTCERKC 2227

HSP 2 Score: 56.9954 bits (136), Expect = 1.172e-10
Identity = 26/53 (49.06%), Postives = 34/53 (64.15%), Query Frame = 1

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 297
            C  P++ G CRG F R+FF++E   C+ F Y GCQGN NNF +  EC A C +
Sbjct:  737 CLHPRDSGNCRGQFVRWFFDDEKKNCDVFTYTGCQGNGNNFASKEECMAICHK 789

HSP 3 Score: 55.0694 bits (131), Expect = 5.841e-10
Identity = 25/63 (39.68%), Postives = 37/63 (58.73%), Query Frame = 1

Query:  103 VAIHLGDCKEPECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
            V +     +   CSLPKE G C  Y  R++FN +  +C+ F +GGC+GN+NNF    +C + C
Sbjct:  527 VGLQTSGARATRCSLPKERGPCDKYELRFYFNADLNECKYFFWGGCEGNQNNFERVEDCESAC 589

HSP 4 Score: 54.299 bits (129), Expect = 1.166e-9
Identity = 25/60 (41.67%), Postives = 35/60 (58.33%), Query Frame = 1

Query:  112 HLGDCKEPECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
            +L    E +C  P E G C+ +  R++FN + G C  F YGGC GN+N+F+T  EC   C
Sbjct: 1074 NLAAQIEEKCLQPVEPGPCKNFADRWYFNVDDGTCHPFKYGGCAGNRNHFFTQKECEVHC 1133

HSP 5 Score: 53.5286 bits (127), Expect = 2.152e-9
Identity = 26/51 (50.98%), Postives = 32/51 (62.75%), Query Frame = 1

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
             SLP   G C G F RYF+NE++ KCE+F Y GC GN NN+ +   C  RC
Sbjct:  426 VSLP---GPCHGSFQRYFYNEDSQKCEQFTYSGCGGNGNNYESREACEDRC 473

HSP 6 Score: 50.0618 bits (118), Expect = 3.380e-8
Identity = 24/51 (47.06%), Postives = 28/51 (54.90%), Query Frame = 1

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
            C    EVG C G F R+ F++    C  F YGGC GN NNF T  EC  +C
Sbjct:  866 CEADIEVGECAGVFSRFAFDKSINACRSFTYGGCGGNANNFATLQECTNKC 916

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Celegans
Match: mlt-11 (pep chromosome:WBcel235:V:20667211:20678513:1 gene:WBGene00012186.1 transcript:W01F3.3d.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:mlt-11)

HSP 1 Score: 65.0846 bits (157), Expect = 1.451e-13
Identity = 29/74 (39.19%), Postives = 42/74 (56.76%), Query Frame = 1

Query:  100 AVAIHLGDCKEPE----------CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
            A  + LG   +P           C++P + G+C  Y PR+FFN +TG+CE+F YG C GN+NNF+    C  +C
Sbjct: 2145 ASVVPLGTTPQPHFEPKFDGRVVCAMPPDAGVCTNYTPRWFFNSQTGQCEQFAYGSCGGNENNFFDRNTCERKC 2218

HSP 2 Score: 56.9954 bits (136), Expect = 1.184e-10
Identity = 26/53 (49.06%), Postives = 34/53 (64.15%), Query Frame = 1

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 297
            C  P++ G CRG F R+FF++E   C+ F Y GCQGN NNF +  EC A C +
Sbjct:  728 CLHPRDSGNCRGQFVRWFFDDEKKNCDVFTYTGCQGNGNNFASKEECMAICHK 780

HSP 3 Score: 55.0694 bits (131), Expect = 6.072e-10
Identity = 25/63 (39.68%), Postives = 37/63 (58.73%), Query Frame = 1

Query:  103 VAIHLGDCKEPECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
            V +     +   CSLPKE G C  Y  R++FN +  +C+ F +GGC+GN+NNF    +C + C
Sbjct:  527 VGLQTSGARATRCSLPKERGPCDKYELRFYFNADLNECKYFFWGGCEGNQNNFERVEDCESAC 589

HSP 4 Score: 53.9138 bits (128), Expect = 1.212e-9
Identity = 25/60 (41.67%), Postives = 35/60 (58.33%), Query Frame = 1

Query:  112 HLGDCKEPECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
            +L    E +C  P E G C+ +  R++FN + G C  F YGGC GN+N+F+T  EC   C
Sbjct: 1065 NLAAQIEEKCLQPVEPGPCKNFADRWYFNVDDGTCHPFKYGGCAGNRNHFFTQKECEVHC 1124

HSP 5 Score: 53.1434 bits (126), Expect = 2.237e-9
Identity = 26/51 (50.98%), Postives = 32/51 (62.75%), Query Frame = 1

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
             SLP   G C G F RYF+NE++ KCE+F Y GC GN NN+ +   C  RC
Sbjct:  426 VSLP---GPCHGSFQRYFYNEDSQKCEQFTYSGCGGNGNNYESREACEDRC 473

HSP 6 Score: 50.0618 bits (118), Expect = 3.480e-8
Identity = 24/51 (47.06%), Postives = 28/51 (54.90%), Query Frame = 1

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
            C    EVG C G F R+ F++    C  F YGGC GN NNF T  EC  +C
Sbjct:  857 CEADIEVGECAGVFSRFAFDKSINACRSFTYGGCGGNANNFATLQECTNKC 907

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Celegans
Match: mlt-11 (pep chromosome:WBcel235:V:20667211:20678513:1 gene:WBGene00012186.1 transcript:W01F3.3e.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:mlt-11)

HSP 1 Score: 65.0846 bits (157), Expect = 1.563e-13
Identity = 29/74 (39.19%), Postives = 42/74 (56.76%), Query Frame = 1

Query:  100 AVAIHLGDCKEPE----------CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
            A  + LG   +P           C++P + G+C  Y PR+FFN +TG+CE+F YG C GN+NNF+    C  +C
Sbjct: 1628 ASVVPLGTTPQPHFEPKFDGRVVCAMPPDAGVCTNYTPRWFFNSQTGQCEQFAYGSCGGNENNFFDRNTCERKC 1701

HSP 2 Score: 56.9954 bits (136), Expect = 9.713e-11
Identity = 26/53 (49.06%), Postives = 34/53 (64.15%), Query Frame = 1

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 297
            C  P++ G CRG F R+FF++E   C+ F Y GCQGN NNF +  EC A C +
Sbjct:  737 CLHPRDSGNCRGQFVRWFFDDEKKNCDVFTYTGCQGNGNNFASKEECMAICHK 789

HSP 3 Score: 55.0694 bits (131), Expect = 5.386e-10
Identity = 25/64 (39.06%), Postives = 37/64 (57.81%), Query Frame = 1

Query:  100 AVAIHLGDCKEPECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
             V +     +   CSLPKE G C  Y  R++FN +  +C+ F +GGC+GN+NNF    +C + C
Sbjct:  526 VVGLQTSGARATRCSLPKERGPCDKYELRFYFNADLNECKYFFWGGCEGNQNNFERVEDCESAC 589

HSP 4 Score: 54.299 bits (129), Expect = 1.054e-9
Identity = 25/58 (43.10%), Postives = 35/58 (60.34%), Query Frame = 1

Query:  130 EPECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ*L 303
            E +C  P E G C+ +  R++FN + G C  F YGGC GN+N+F+T  EC   C + L
Sbjct: 1080 EEKCLQPVEPGPCKNFADRWYFNVDDGTCHPFKYGGCAGNRNHFFTQKECEVHCARFL 1137

HSP 5 Score: 53.1434 bits (126), Expect = 2.296e-9
Identity = 26/50 (52.00%), Postives = 32/50 (64.00%), Query Frame = 1

Query:  142 SLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
            SLP   G C G F RYF+NE++ KCE+F Y GC GN NN+ +   C  RC
Sbjct:  427 SLP---GPCHGSFQRYFYNEDSQKCEQFTYSGCGGNGNNYESREACEDRC 473

HSP 6 Score: 50.0618 bits (118), Expect = 2.827e-8
Identity = 24/51 (47.06%), Postives = 28/51 (54.90%), Query Frame = 1

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
            C    EVG C G F R+ F++    C  F YGGC GN NNF T  EC  +C
Sbjct:  866 CEADIEVGECAGVFSRFAFDKSINACRSFTYGGCGGNANNFATLQECTNKC 916

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Celegans
Match: mlt-11 (pep chromosome:WBcel235:V:20667209:20678513:1 gene:WBGene00012186.1 transcript:W01F3.3f.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:mlt-11)

HSP 1 Score: 65.0846 bits (157), Expect = 1.606e-13
Identity = 29/74 (39.19%), Postives = 42/74 (56.76%), Query Frame = 1

Query:  100 AVAIHLGDCKEPE----------CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
            A  + LG   +P           C++P + G+C  Y PR+FFN +TG+CE+F YG C GN+NNF+    C  +C
Sbjct: 1407 ASVVPLGTTPQPHFEPKFDGRVVCAMPPDAGVCTNYTPRWFFNSQTGQCEQFAYGSCGGNENNFFDRNTCERKC 1480

HSP 2 Score: 57.3806 bits (137), Expect = 9.326e-11
Identity = 26/53 (49.06%), Postives = 34/53 (64.15%), Query Frame = 1

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 297
            C  P++ G CRG F R+FF++E   C+ F Y GCQGN NNF +  EC A C +
Sbjct:  516 CLHPRDSGNCRGQFVRWFFDDEKKNCDVFTYTGCQGNGNNFASKEECMAICHK 568

HSP 3 Score: 55.0694 bits (131), Expect = 5.324e-10
Identity = 25/64 (39.06%), Postives = 37/64 (57.81%), Query Frame = 1

Query:  100 AVAIHLGDCKEPECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
             V +     +   CSLPKE G C  Y  R++FN +  +C+ F +GGC+GN+NNF    +C + C
Sbjct:  305 VVGLQTSGARATRCSLPKERGPCDKYELRFYFNADLNECKYFFWGGCEGNQNNFERVEDCESAC 368

HSP 4 Score: 54.299 bits (129), Expect = 9.362e-10
Identity = 25/58 (43.10%), Postives = 35/58 (60.34%), Query Frame = 1

Query:  130 EPECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ*L 303
            E +C  P E G C+ +  R++FN + G C  F YGGC GN+N+F+T  EC   C + L
Sbjct:  859 EEKCLQPVEPGPCKNFADRWYFNVDDGTCHPFKYGGCAGNRNHFFTQKECEVHCARFL 916

HSP 5 Score: 53.1434 bits (126), Expect = 2.360e-9
Identity = 26/50 (52.00%), Postives = 32/50 (64.00%), Query Frame = 1

Query:  142 SLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
            SLP   G C G F RYF+NE++ KCE+F Y GC GN NN+ +   C  RC
Sbjct:  206 SLP---GPCHGSFQRYFYNEDSQKCEQFTYSGCGGNGNNYESREACEDRC 252

HSP 6 Score: 50.447 bits (119), Expect = 2.586e-8
Identity = 24/51 (47.06%), Postives = 28/51 (54.90%), Query Frame = 1

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
            C    EVG C G F R+ F++    C  F YGGC GN NNF T  EC  +C
Sbjct:  645 CEADIEVGECAGVFSRFAFDKSINACRSFTYGGCGGNANNFATLQECTNKC 695

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Fly
Match: CG3604 (gene:FBgn0031562 transcript:FBtr0077545)

HSP 1 Score: 61.6178 bits (148), Expect = 3.240e-13
Identity = 34/68 (50.00%), Postives = 40/68 (58.82%), Query Frame = 1

Query:  100 AVAIHLGDCKE---PE-CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
            AVA  L D  E   PE C  PKE G C   F RY +N +T  CE+F+YGGC GNKNNF +  +C   C
Sbjct:   38 AVAKPLPDASELTVPEDCHQPKETGRCFALFYRYAYNVDTQSCEEFVYGGCAGNKNNFESKEQCEQAC 105

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Fly
Match: CG3604 (gene:FBgn0031562 transcript:FBtr0346581)

HSP 1 Score: 61.6178 bits (148), Expect = 3.240e-13
Identity = 34/68 (50.00%), Postives = 40/68 (58.82%), Query Frame = 1

Query:  100 AVAIHLGDCKE---PE-CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
            AVA  L D  E   PE C  PKE G C   F RY +N +T  CE+F+YGGC GNKNNF +  +C   C
Sbjct:   38 AVAKPLPDASELTVPEDCHQPKETGRCFALFYRYAYNVDTQSCEEFVYGGCAGNKNNFESKEQCEQAC 105

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Fly
Match: CG15418 (gene:FBgn0031554 transcript:FBtr0077556)

HSP 1 Score: 60.4622 bits (145), Expect = 4.442e-13
Identity = 30/55 (54.55%), Postives = 35/55 (63.64%), Query Frame = 1

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ*L 303
            C  PK  GLCRG+  RY +N++TG CE FIY GC   +NNF T  ECR  C Q L
Sbjct:   41 CRQPKAPGLCRGHQLRYAYNKKTGNCESFIYTGCASTENNFLTFEECRRDCMQRL 95

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Fly
Match: CG15418 (gene:FBgn0031554 transcript:FBtr0446100)

HSP 1 Score: 60.4622 bits (145), Expect = 4.442e-13
Identity = 30/55 (54.55%), Postives = 35/55 (63.64%), Query Frame = 1

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ*L 303
            C  PK  GLCRG+  RY +N++TG CE FIY GC   +NNF T  ECR  C Q L
Sbjct:   41 CRQPKAPGLCRGHQLRYAYNKKTGNCESFIYTGCASTENNFLTFEECRRDCMQRL 95

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Fly
Match: IM33 (gene:FBgn0031561 transcript:FBtr0077546)

HSP 1 Score: 54.299 bits (129), Expect = 5.742e-11
Identity = 31/70 (44.29%), Postives = 42/70 (60.00%), Query Frame = 1

Query:  103 VAIHLGDCKEPECSLPKEV---GL--CRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 297
            VA+ LG  K+P C LP  +   GL  C  + P + ++ ET  CEKFIYGGC GN+N F T   C  +C++
Sbjct:   14 VAVALG-LKDPICGLPAGIDGNGLIKCAAFIPSFSYHPETNSCEKFIYGGCGGNENRFGTQELCEQKCKE 82

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Zebrafish
Match: spint2 (serine peptidase inhibitor, Kunitz type, 2 [Source:ZFIN;Acc:ZDB-GENE-061013-323])

HSP 1 Score: 62.7734 bits (151), Expect = 1.653e-12
Identity = 27/51 (52.94%), Postives = 33/51 (64.71%), Query Frame = 1

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
            C  P  VG CR  FPR+F++     C+ FIYGGC GN+NNFY+  EC A C
Sbjct:  133 CRFPSAVGNCRAAFPRFFYDITDQTCKSFIYGGCGGNENNFYSQAECEASC 183

HSP 2 Score: 50.0618 bits (118), Expect = 4.553e-8
Identity = 22/54 (40.74%), Postives = 32/54 (59.26%), Query Frame = 1

Query:  130 EPECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
            E +C +P + G CR  F  +FF   +  C+ FIYGGC+GN N + +  EC + C
Sbjct:  301 EEKCVVPSDSGPCRASFRMFFFEASSQSCQPFIYGGCRGNLNRYGSEEECMSVC 354

HSP 3 Score: 48.1358 bits (113), Expect = 2.161e-7
Identity = 22/54 (40.74%), Postives = 31/54 (57.41%), Query Frame = 1

Query:  130 EPECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
            + +C  P   G CR    R+++N   G C++FIYGGC GNKNN+ +   C   C
Sbjct:  225 QEKCQSPAVTGNCRASIKRFYYN--NGVCQQFIYGGCGGNKNNYESEDSCMTAC 276

[Close]

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
            C  P  VG CR  FPR+F++     C+ FIYGGC GN+NNFY+  EC A C
Sbjct:  133 CRFPSAVGNCRAAFPRFFYDITDQTCKSFIYGGCGGNENNFYSQAECEASC 183

HSP 2 Score: 50.0618 bits (118), Expect = 4.379e-8
Identity = 22/54 (40.74%), Postives = 32/54 (59.26%), Query Frame = 1

Query:  130 EPECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
            E +C +P + G CR  F  +FF   +  C+ FIYGGC+GN N + +  EC + C
Sbjct:  301 EEKCVVPSDSGPCRASFRMFFFEASSQSCQPFIYGGCRGNLNRYGSEEECMSVC 354

HSP 3 Score: 48.1358 bits (113), Expect = 2.140e-7
Identity = 22/54 (40.74%), Postives = 31/54 (57.41%), Query Frame = 1

Query:  130 EPECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
            + +C  P   G CR    R+++N   G C++FIYGGC GNKNN+ +   C   C
Sbjct:  225 QEKCQSPAVTGNCRASIKRFYYN--NGVCQQFIYGGCGGNKNNYESEDSCMTAC 276

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Zebrafish
Match: wfikkn1 (WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 [Source:NCBI gene;Acc:406570])

HSP 1 Score: 62.3882 bits (150), Expect = 2.408e-12
Identity = 28/51 (54.90%), Postives = 34/51 (66.67%), Query Frame = 1

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
            CSLP   G CR +  R+F+N  T +CE F+YGGC GNKN+F T  EC A C
Sbjct:  257 CSLPAVQGPCRHWQARWFYNSLTERCEAFLYGGCSGNKNSFGTRRECDAHC 307

HSP 2 Score: 44.2838 bits (103), Expect = 4.344e-6
Identity = 26/67 (38.81%), Postives = 36/67 (53.73%), Query Frame = 1

Query:  100 AVAIHLGDCKEP-ECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 297
            A  + LG    P +CS   E G C      +FF+   G C  F +GGC+G +N F+T  ECRA C++
Sbjct:  186 AAGLPLGRPFSPADCSAAVERGDCGEKRVDWFFDPARGSCHTFTHGGCEG-RNRFHTFEECRASCQR 251

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Zebrafish
Match: aplp2 (amyloid beta (A4) precursor-like protein 2 [Source:ZFIN;Acc:ZDB-GENE-061009-28])

HSP 1 Score: 61.6178 bits (148), Expect = 3.753e-12
Identity = 26/56 (46.43%), Postives = 34/56 (60.71%), Query Frame = 1

Query:  130 EPECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 297
            E  CSL  E G CR   PR+ F+ +  KC +FIYGGC GN+NNF +   C   C++
Sbjct:  312 EAVCSLEAETGPCRASMPRWHFDMQQRKCVRFIYGGCAGNRNNFDSEEYCMVVCKR 367

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Zebrafish
Match: aplp2 (amyloid beta (A4) precursor-like protein 2 [Source:ZFIN;Acc:ZDB-GENE-061009-28])

HSP 1 Score: 61.6178 bits (148), Expect = 3.831e-12
Identity = 26/56 (46.43%), Postives = 34/56 (60.71%), Query Frame = 1

Query:  130 EPECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 297
            E  CSL  E G CR   PR+ F+ +  KC +FIYGGC GN+NNF +   C   C++
Sbjct:  312 EAVCSLEAETGPCRASMPRWHFDMQQRKCVRFIYGGCAGNRNNFDSEEYCMVVCKR 367

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Xenopus
Match: itch (itchy E3 ubiquitin protein ligase [Source:Xenbase;Acc:XB-GENE-976485])

HSP 1 Score: 60.4622 bits (145), Expect = 1.843e-11
Identity = 25/54 (46.30%), Postives = 34/54 (62.96%), Query Frame = 1

Query:  133 PE-CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
            PE C+L KE G CR +  +++++ ET  C +F YGGC GN+N F T  EC   C
Sbjct: 2826 PEVCNLQKEEGTCRDFVLKWYYDPETKSCARFWYGGCGGNENRFSTQKECEKIC 2879

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Xenopus
Match: itch (itchy E3 ubiquitin protein ligase [Source:Xenbase;Acc:XB-GENE-976485])

HSP 1 Score: 60.4622 bits (145), Expect = 1.845e-11
Identity = 25/54 (46.30%), Postives = 34/54 (62.96%), Query Frame = 1

Query:  133 PE-CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
            PE C+L KE G CR +  +++++ ET  C +F YGGC GN+N F T  EC   C
Sbjct: 3006 PEVCNLQKEEGTCRDFVLKWYYDPETKSCARFWYGGCGGNENRFSTQKECEKIC 3059

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Xenopus
Match: itch (itchy E3 ubiquitin protein ligase [Source:Xenbase;Acc:XB-GENE-976485])

HSP 1 Score: 60.4622 bits (145), Expect = 1.845e-11
Identity = 25/54 (46.30%), Postives = 34/54 (62.96%), Query Frame = 1

Query:  133 PE-CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
            PE C+L KE G CR +  +++++ ET  C +F YGGC GN+N F T  EC   C
Sbjct: 3023 PEVCNLQKEEGTCRDFVLKWYYDPETKSCARFWYGGCGGNENRFSTQKECEKIC 3076

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Xenopus
Match: rlbp1 (retinaldehyde binding protein 1 [Source:Xenbase;Acc:XB-GENE-976303])

HSP 1 Score: 59.6918 bits (143), Expect = 2.561e-11
Identity = 27/55 (49.09%), Postives = 34/55 (61.82%), Query Frame = 1

Query:  127 KEPECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
             E  C  P +VG CRG F R++FN ET  C +F YGGC+ NKNN+    +CR  C
Sbjct:  236 TEEHCFAPHKVGRCRGSFTRWYFNPETNDCLEFTYGGCKPNKNNYLRIEDCRQTC 290

HSP 2 Score: 50.8322 bits (120), Expect = 4.055e-8
Identity = 22/57 (38.60%), Postives = 31/57 (54.39%), Query Frame = 1

Query:  124 CKEPECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCE 294
            C+   C    + G CR  F R++++    KC +F YGGC GN NNF+   +C   CE
Sbjct:  353 CENSRCVDLPDTGPCRASFSRFYYDPNIRKCLRFTYGGCAGNDNNFHRESDCMRYCE 409

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Xenopus
Match: PAPLN (papilin, proteoglycan-like sulfated glycoprotein [Source:NCBI gene;Acc:100489537])

HSP 1 Score: 59.6918 bits (143), Expect = 2.581e-11
Identity = 26/53 (49.06%), Postives = 32/53 (60.38%), Query Frame = 1

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 297
            C LP   G C  +  R++F  E GKC +F YG C GNKNNF T  EC + C+Q
Sbjct:  666 CLLPSATGSCADWSTRWYFVPEVGKCNRFWYGNCHGNKNNFATEQECMSSCQQ 718

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Mouse
Match: Spint3 (serine peptidase inhibitor, Kunitz type, 3 [Source:MGI Symbol;Acc:MGI:3651470])

HSP 1 Score: 66.2402 bits (160), Expect = 2.668e-15
Identity = 29/53 (54.72%), Postives = 40/53 (75.47%), Query Frame = 1

Query:  133 PECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
            P C LPK++G CR  F R+++N +TGKCE F YGGC+GN+NNF +  +C+A C
Sbjct:   33 PMCILPKDIGGCRAVFVRWYYNSKTGKCEWFRYGGCKGNENNFPSRSQCQAVC 85

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Mouse
Match: Eppin (epididymal peptidase inhibitor [Source:MGI Symbol;Acc:MGI:1922776])

HSP 1 Score: 65.855 bits (159), Expect = 9.164e-15
Identity = 29/53 (54.72%), Postives = 37/53 (69.81%), Query Frame = 1

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 297
            CSLPK+ G C  YF R++FN+E   C+ FIYGGCQGN NNF +   C+  CE+
Sbjct:   77 CSLPKDSGYCMAYFRRWWFNKENSTCQVFIYGGCQGNNNNFQSQSICQNACEK 129

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Mouse
Match: Tfpi (tissue factor pathway inhibitor [Source:MGI Symbol;Acc:MGI:1095418])

HSP 1 Score: 67.0106 bits (162), Expect = 2.329e-14
Identity = 29/53 (54.72%), Postives = 38/53 (71.70%), Query Frame = 1

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 297
            C L ++ GLCRGY  RY +N +T +CE+F+YGGC GN+NNF T  EC+  CE 
Sbjct:  121 CFLEEDPGLCRGYMKRYLYNNQTKQCERFVYGGCLGNRNNFETLDECKKICEN 173

HSP 2 Score: 53.5286 bits (127), Expect = 1.987e-9
Identity = 24/51 (47.06%), Postives = 33/51 (64.71%), Query Frame = 1

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
            C++  + G C+     YFFN  T +CE+FIYGGC+GN+N F T  EC+  C
Sbjct:   50 CAMKADDGPCKAMIRSYFFNMYTHQCEEFIYGGCEGNENRFDTLEECKKTC 100

[Close]

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 297
            C L ++ GLCRGY  RY +N +T +CE+F+YGGC GN+NNF T  EC+  CE 
Sbjct:  121 CFLEEDPGLCRGYMKRYLYNNQTKQCERFVYGGCLGNRNNFETLDECKKICEN 173

HSP 2 Score: 53.5286 bits (127), Expect = 1.987e-9
Identity = 24/51 (47.06%), Postives = 33/51 (64.71%), Query Frame = 1

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
            C++  + G C+     YFFN  T +CE+FIYGGC+GN+N F T  EC+  C
Sbjct:   50 CAMKADDGPCKAMIRSYFFNMYTHQCEEFIYGGCEGNENRFDTLEECKKTC 100

[Close]

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 297
            C L ++ GLCRGY  RY +N +T +CE+F+YGGC GN+NNF T  EC+  CE 
Sbjct:  121 CFLEEDPGLCRGYMKRYLYNNQTKQCERFVYGGCLGNRNNFETLDECKKICEN 173

HSP 2 Score: 53.5286 bits (127), Expect = 1.987e-9
Identity = 24/51 (47.06%), Postives = 33/51 (64.71%), Query Frame = 1

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
            C++  + G C+     YFFN  T +CE+FIYGGC+GN+N F T  EC+  C
Sbjct:   50 CAMKADDGPCKAMIRSYFFNMYTHQCEEFIYGGCEGNENRFDTLEECKKTC 100

[Close]

BLAST of Kunitz-type protease inhibitor vs. UniProt/SwissProt
Match: sp|P0DMW6|VKT3A_ACTEQ (PI-actitoxin-Aeq3a OS=Actinia equina OX=6106 PE=1 SV=1)

HSP 1 Score: 76.2554 bits (186), Expect = 8.397e-19
Identity = 34/53 (64.15%), Postives = 40/53 (75.47%), Query Frame = 1

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 297
            C LP  VG CRGYFPRY++N E GKC++FIYGGC GN+NNF T  +CRA C  
Sbjct:    6 CQLPAVVGKCRGYFPRYYYNTEAGKCQQFIYGGCGGNRNNFETVEDCRATCHS 58

[Close]

BLAST of Kunitz-type protease inhibitor vs. UniProt/SwissProt
Match: sp|P0DMW7|VKT3B_ACTEQ (PI-actitoxin-Aeq3b OS=Actinia equina OX=6106 PE=1 SV=1)

HSP 1 Score: 75.0998 bits (183), Expect = 2.451e-18
Identity = 33/53 (62.26%), Postives = 40/53 (75.47%), Query Frame = 1

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 297
            C LP  VG CRGYFPR+++N E GKC++FIYGGC GN+NNF T  +CRA C  
Sbjct:    6 CQLPAVVGKCRGYFPRFYYNTEAGKCQQFIYGGCGGNRNNFETVEDCRATCHS 58

[Close]

BLAST of Kunitz-type protease inhibitor vs. UniProt/SwissProt
Match: sp|P0DJ50|VKT31_MESMA (Kunitz-type serine protease inhibitor BmKTT-2 OS=Mesobuthus martensii OX=34649 PE=2 SV=2)

HSP 1 Score: 73.9442 bits (180), Expect = 1.370e-17
Identity = 29/66 (43.94%), Postives = 45/66 (68.18%), Query Frame = 1

Query:   97 FAVAIHLGDCKEPECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCE 294
             +V   + D +  +C+LP + G C+ YF RYF+N++ G+C+KF+YGGC+GN NNF T  +C  +C 
Sbjct:   12 LSVVCTISDAEGVDCTLPSDTGRCKAYFIRYFYNQKAGECQKFVYGGCEGNSNNFLTKSDCCKQCS 77

[Close]

BLAST of Kunitz-type protease inhibitor vs. UniProt/SwissProt
Match: sp|P0DMX0|VKT3_ANTAF (PI-actitoxin-Axm2b OS=Anthopleura aff. xanthogrammica OX=152178 PE=1 SV=1)

HSP 1 Score: 72.4034 bits (176), Expect = 3.468e-17
Identity = 34/51 (66.67%), Postives = 39/51 (76.47%), Query Frame = 1

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
            C LP   G CRGYFPRYFF+ ETGKCE+FIYGGC GN+NNF +  EC + C
Sbjct:    7 CYLPAVRGRCRGYFPRYFFSSETGKCERFIYGGCGGNRNNFESAQECGSTC 57

[Close]

BLAST of Kunitz-type protease inhibitor vs. UniProt/SwissProt
Match: sp|B1B5I8|VKT3_STIHA (KappaPI-stichotoxin-Shd2a OS=Stichodactyla haddoni OX=475174 PE=1 SV=1)

HSP 1 Score: 70.4774 bits (171), Expect = 2.902e-16
Identity = 33/51 (64.71%), Postives = 38/51 (74.51%), Query Frame = 1

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
            C L  +V  CRGYFPRY++N E GKCE+FIYGGC GNKNNF +   CRA C
Sbjct:   27 CHLQPDVPKCRGYFPRYYYNPEVGKCEQFIYGGCGGNKNNFVSFEACRATC 77

[Close]

BLAST of Kunitz-type protease inhibitor vs. TrEMBL
Match: I1ZII0 (Serine protease inhibitor-1 (Fragment) OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 76.2554 bits (186), Expect = 3.394e-16
Identity = 33/59 (55.93%), Postives = 42/59 (71.19%), Query Frame = 1

Query:  121 DCKEPECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 297
             C    CSLPK  G C+ YFPRY++N +TGKCEKFIYGGC+GN+NNF +  +C   C +
Sbjct:   17 SCLNSICSLPKNAGPCKAYFPRYYYNSKTGKCEKFIYGGCKGNQNNFQSSKDCEQNCHK 75

[Close]

BLAST of Kunitz-type protease inhibitor vs. TrEMBL
Match: C8YJ95 (Serine protease inhibitor 3 OS=Tabanus yao OX=485572 PE=2 SV=1)

HSP 1 Score: 75.8702 bits (185), Expect = 6.080e-16
Identity = 33/65 (50.77%), Postives = 43/65 (66.15%), Query Frame = 1

Query:   97 FAVAIHLGDCKEPECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
            F+V +     K+P C  PK VG C   FP+++FN  +G+CE FIYGGC GN+NNF T  EC A+C
Sbjct:   11 FSVLVLFASAKDPVCDQPKAVGRCFAAFPKFYFNSSSGQCEAFIYGGCGGNENNFSTLEECNAKC 75

[Close]

BLAST of Kunitz-type protease inhibitor vs. TrEMBL
Match: C1IBY4 (Tabserpin OS=Tabanus yao OX=485572 PE=2 SV=1)

HSP 1 Score: 75.485 bits (184), Expect = 8.718e-16
Identity = 33/65 (50.77%), Postives = 43/65 (66.15%), Query Frame = 1

Query:   97 FAVAIHLGDCKEPECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
            F+V +     K+P C  PK VG C   FP+++FN  +G+CE FIYGGC GN+NNF T  EC A+C
Sbjct:   11 FSVLVLFASAKDPVCDQPKAVGRCFAAFPKFYFNSSSGQCEAFIYGGCGGNENNFNTLEECNAKC 75

[Close]

BLAST of Kunitz-type protease inhibitor vs. TrEMBL
Match: A0A1V0FWP9 (Venom kunitz type-like peptide Vf1 (Fragment) OS=Viridasius fasciatus OX=1971609 PE=2 SV=1)

HSP 1 Score: 73.559 bits (179), Expect = 3.327e-15
Identity = 31/51 (60.78%), Postives = 40/51 (78.43%), Query Frame = 1

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
            C LP E G+CRG+FPRY+F+  TG+C+KF+YGGC GN+NNF T  EC+  C
Sbjct:    9 CDLPAETGVCRGFFPRYYFDRTTGQCQKFVYGGCGGNENNFETVEECQRTC 59

[Close]

BLAST of Kunitz-type protease inhibitor vs. TrEMBL
Match: A7T2J6 (Predicted protein OS=Nematostella vectensis OX=45351 GN=v1g143195 PE=4 SV=1)

HSP 1 Score: 73.559 bits (179), Expect = 3.391e-15
Identity = 32/51 (62.75%), Postives = 38/51 (74.51%), Query Frame = 1

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
            C+LPK+VG CR   PR FFN ++GKCE FIYGGC GN NNF+T  EC+  C
Sbjct:   14 CTLPKKVGDCRAAMPRVFFNSQSGKCEDFIYGGCGGNANNFHTMEECKKAC 64

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Cavefish
Match: lrp11 (LDL receptor related protein 11 [Source:NCBI gene;Acc:103032685])

HSP 1 Score: 64.6994 bits (156), Expect = 2.812e-13
Identity = 25/53 (47.17%), Postives = 35/53 (66.04%), Query Frame = 1

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 297
            C  P  VG CRG FPR++++   G+C+ F+YGGC+GN+NNF    +C   C Q
Sbjct:  417 CMEPPVVGPCRGTFPRWYYDAAAGECKHFLYGGCKGNRNNFLQQTDCVNECIQ 469

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Cavefish
Match: lrp11 (LDL receptor related protein 11 [Source:NCBI gene;Acc:103032685])

HSP 1 Score: 63.929 bits (154), Expect = 6.277e-13
Identity = 25/53 (47.17%), Postives = 35/53 (66.04%), Query Frame = 1

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 297
            C  P  VG CRG FPR++++   G+C+ F+YGGC+GN+NNF    +C   C Q
Sbjct:  417 CMEPPVVGPCRGTFPRWYYDAAAGECKHFLYGGCKGNRNNFLQQTDCVNECIQ 469

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Cavefish
Match: aplp2 (amyloid beta precursor like protein 2 [Source:NCBI gene;Acc:103022515])

HSP 1 Score: 62.7734 bits (151), Expect = 1.610e-12
Identity = 26/53 (49.06%), Postives = 34/53 (64.15%), Query Frame = 1

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 297
            CSL  E G CR   PR+ F+ +  KC +FIYGGC GN+NNF +   C A C++
Sbjct:  315 CSLEAETGPCRASMPRWHFDMQQRKCVRFIYGGCAGNRNNFDSEEYCMAVCKR 367

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Cavefish
Match: aplp2 (amyloid beta precursor like protein 2 [Source:NCBI gene;Acc:103022515])

HSP 1 Score: 62.3882 bits (150), Expect = 1.743e-12
Identity = 26/53 (49.06%), Postives = 34/53 (64.15%), Query Frame = 1

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 297
            CSL  E G CR   PR+ F+ +  KC +FIYGGC GN+NNF +   C A C++
Sbjct:  315 CSLEAETGPCRASMPRWHFDMQQRKCVRFIYGGCAGNRNNFDSEEYCMAVCKR 367

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Cavefish
Match: aplp2 (amyloid beta precursor like protein 2 [Source:NCBI gene;Acc:103022515])

HSP 1 Score: 62.003 bits (149), Expect = 2.328e-12
Identity = 26/53 (49.06%), Postives = 34/53 (64.15%), Query Frame = 1

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 297
            CSL  E G CR   PR+ F+ +  KC +FIYGGC GN+NNF +   C A C++
Sbjct:  315 CSLEAETGPCRASMPRWHFDMQQRKCVRFIYGGCAGNRNNFDSEEYCMAVCKR 367

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Sea Lamprey
Match: tfpi2 (tissue factor pathway inhibitor 2 [Source:ZFIN;Acc:ZDB-GENE-060503-38])

HSP 1 Score: 69.707 bits (169), Expect = 2.985e-16
Identity = 32/52 (61.54%), Postives = 36/52 (69.23%), Query Frame = 1

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCE 294
            C+LP + G CR  FPRYFFN  T +CE FIYGGC  N+NNF T  ECRA C 
Sbjct:   27 CTLPAKPGDCRAAFPRYFFNRSTLRCESFIYGGCHSNENNFETMQECRAACS 78

HSP 2 Score: 45.8246 bits (107), Expect = 1.855e-7
Identity = 22/51 (43.14%), Postives = 25/51 (49.02%), Query Frame = 1

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
            C    E G CR +  RYF+N   G C  F+YGGC GN N F     C   C
Sbjct:   87 CRPDAETGRCRAHITRYFYNMTLGMCMPFVYGGCGGNNNRFEDMESCVFSC 137

HSP 3 Score: 43.1282 bits (100), Expect = 2.051e-6
Identity = 20/52 (38.46%), Postives = 28/52 (53.85%), Query Frame = 1

Query:  136 ECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
            EC    + G C+G F R+++N +   C  F Y GC GN NNF +   C + C
Sbjct:  146 ECLSRHDTGNCQGNFRRFYYNIQKRSCLPFSYSGCGGNNNNFISAKTCLSTC 197

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005038.1 (pep scaffold:Pmarinus_7.0:GL481015:31246:35903:1 gene:ENSPMAG00000004579.1 transcript:ENSPMAT00000005038.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 60.077 bits (144), Expect = 1.104e-12
Identity = 29/57 (50.88%), Postives = 32/57 (56.14%), Query Frame = 1

Query:  121 DCKEPECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
            D     C L  EVG+CR    RYFFN  +G CE+F YGGCQGN NNF     C   C
Sbjct:   69 DIAPKACRLDMEVGVCRALLRRYFFNMTSGSCEEFGYGGCQGNLNNFKDAASCYQHC 125

HSP 2 Score: 55.8398 bits (133), Expect = 3.941e-11
Identity = 26/52 (50.00%), Postives = 32/52 (61.54%), Query Frame = 1

Query:  136 ECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
             C +  + G CR Y PR F+N  T +CE F YGGC GN NNF +  EC A+C
Sbjct:    2 SCMMDLDPGPCRAYLPRVFYNRYTQRCEPFHYGGCFGNGNNFESLAECNAKC 53

HSP 3 Score: 49.6766 bits (117), Expect = 8.313e-9
Identity = 22/53 (41.51%), Postives = 29/53 (54.72%), Query Frame = 1

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 297
            C +  + G C    PR+ +N +T  CE F YGGC GN NNF +   C + C Q
Sbjct:  167 CLMKADPGECTAVIPRFHYNPKTSNCESFTYGGCGGNDNNFSSERSCMSVCGQ 219

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005043.1 (pep scaffold:Pmarinus_7.0:GL481015:31246:35903:1 gene:ENSPMAG00000004579.1 transcript:ENSPMAT00000005043.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 59.3066 bits (142), Expect = 2.342e-12
Identity = 28/51 (54.90%), Postives = 31/51 (60.78%), Query Frame = 1

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
            C L  EVG+CR    RYFFN  +G CE+F YGGCQGN NNF     C   C
Sbjct:   74 CRLDMEVGVCRALLRRYFFNMTSGSCEEFGYGGCQGNLNNFKDAASCYQHC 124

HSP 2 Score: 55.8398 bits (133), Expect = 4.112e-11
Identity = 26/52 (50.00%), Postives = 32/52 (61.54%), Query Frame = 1

Query:  136 ECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
             C +  + G CR Y PR F+N  T +CE F YGGC GN NNF +  EC A+C
Sbjct:    2 SCMMDLDPGPCRAYLPRVFYNRYTQRCEPFHYGGCFGNGNNFESLAECNAKC 53

HSP 3 Score: 49.6766 bits (117), Expect = 8.262e-9
Identity = 22/53 (41.51%), Postives = 29/53 (54.72%), Query Frame = 1

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 297
            C +  + G C    PR+ +N +T  CE F YGGC GN NNF +   C + C Q
Sbjct:  166 CLMKADPGECTAVIPRFHYNPKTSNCESFTYGGCGGNDNNFSSERSCMSVCGQ 218

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009465.1 (pep scaffold:Pmarinus_7.0:GL478507:22936:25713:-1 gene:ENSPMAG00000008558.1 transcript:ENSPMAT00000009465.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 53.5286 bits (127), Expect = 3.921e-10
Identity = 24/51 (47.06%), Postives = 31/51 (60.78%), Query Frame = 1

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
            C L + VG CRG F R+ ++ E+  C++F YGGC GN NNF    EC   C
Sbjct:   72 CLLEEAVGPCRGSFTRWIYDAESSNCKEFTYGGCGGNFNNFLEETECMVTC 122

HSP 2 Score: 51.2174 bits (121), Expect = 2.229e-9
Identity = 23/51 (45.10%), Postives = 30/51 (58.82%), Query Frame = 1

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
            C L    G CRG F R+ ++  T  C++F YGGC+GN+NNF    EC   C
Sbjct:    1 CLLNPTTGPCRGSFTRWTYDAATSTCKEFTYGGCRGNQNNFLEEAECLMDC 51

HSP 3 Score: 51.2174 bits (121), Expect = 2.438e-9
Identity = 24/54 (44.44%), Postives = 31/54 (57.41%), Query Frame = 1

Query:  130 EPECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
            +  C L      CRG F R+ ++ E+G C++F YGGC GN NNF    EC A C
Sbjct:  163 QDVCLLEAVTSPCRGSFTRWTYDAESGHCKEFTYGGCGGNFNNFLEETECVAMC 216

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Sea Lamprey
Match: WFIKKN1 (WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30912])

HSP 1 Score: 51.2174 bits (121), Expect = 3.326e-9
Identity = 22/51 (43.14%), Postives = 32/51 (62.75%), Query Frame = 1

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
            CSLP + G C+ +  R+ +N    +C+ FIYGGC+GN+NNF +   C   C
Sbjct:  374 CSLPVQQGPCKQWALRWAYNPLIKRCQSFIYGGCEGNENNFQSQELCEDNC 424

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Nematostella
Match: EDO29819 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T2J6])

HSP 1 Score: 73.559 bits (179), Expect = 4.690e-19
Identity = 32/51 (62.75%), Postives = 38/51 (74.51%), Query Frame = 1

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
            C+LPK+VG CR   PR FFN ++GKCE FIYGGC GN NNF+T  EC+  C
Sbjct:   14 CTLPKKVGDCRAAMPRVFFNSQSGKCEDFIYGGCGGNANNFHTMEECKKAC 64

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Nematostella
Match: EDO41696 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S3T1])

HSP 1 Score: 65.4698 bits (158), Expect = 5.908e-16
Identity = 28/52 (53.85%), Postives = 37/52 (71.15%), Query Frame = 1

Query:  136 ECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
            EC  PK  G CR YF R+F+N+ + KC++F+YGGCQGN NNF +  EC  +C
Sbjct:    1 ECLQPKLTGPCRAYFERWFYNQTSRKCKQFVYGGCQGNSNNFESKAECEKKC 52

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Nematostella
Match: EDO26263 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S3T1])

HSP 1 Score: 65.4698 bits (158), Expect = 5.908e-16
Identity = 28/52 (53.85%), Postives = 37/52 (71.15%), Query Frame = 1

Query:  136 ECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
            EC  PK  G CR YF R+F+N+ + KC++F+YGGCQGN NNF +  EC  +C
Sbjct:    1 ECLQPKLTGPCRAYFERWFYNQTSRKCKQFVYGGCQGNSNNFESKAECEKKC 52

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Nematostella
Match: EDO49645 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RFR1])

HSP 1 Score: 62.003 bits (149), Expect = 1.870e-14
Identity = 28/57 (49.12%), Postives = 35/57 (61.40%), Query Frame = 1

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ*LLN 309
            C LPKE GLC G F ++F+N     C+KF YGGC GN N F T   C+  C+  LL+
Sbjct:    4 CQLPKEAGLCEGLFTKWFYNATANHCQKFTYGGCGGNANRFDTKRACKLACKGILLS 60

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Nematostella
Match: EDO31760 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SX09])

HSP 1 Score: 59.6918 bits (143), Expect = 1.260e-13
Identity = 27/51 (52.94%), Postives = 32/51 (62.75%), Query Frame = 1

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
            C LPK  G+CR    R+++N ET KC KF +GGC GN NNF T   CR  C
Sbjct:    1 CDLPKNPGVCRASIQRWYYNNETRKCIKFTFGGCHGNANNFPTKSSCRNAC 51

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Medaka
Match: lrp11 (low-density lipoprotein receptor-related protein 11 [Source:NCBI gene;Acc:101175213])

HSP 1 Score: 65.855 bits (159), Expect = 1.040e-13
Identity = 25/53 (47.17%), Postives = 37/53 (69.81%), Query Frame = 1

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 297
            C     VG C+G FPR+++++ TG+C+ F+YGGCQGN NNF   ++C + C Q
Sbjct:  394 CGADPVVGPCKGTFPRWYYDQNTGECKHFLYGGCQGNHNNFLQELDCISECIQ 446

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Medaka
Match: ENSORLT00000012975.2 (pep primary_assembly:ASM223467v1:12:15740273:15760140:1 gene:ENSORLG00000010354.2 transcript:ENSORLT00000012975.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 63.5438 bits (153), Expect = 1.371e-13
Identity = 30/51 (58.82%), Postives = 35/51 (68.63%), Query Frame = 1

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
            C+   + GLC GYF RYF+N   G+CE FIYGGC GN+NNF T  EC  RC
Sbjct:  125 CAQAPDSGLCFGYFERYFYNFRKGRCEIFIYGGCLGNQNNFLTEKECLQRC 175

HSP 2 Score: 61.6178 bits (148), Expect = 9.105e-13
Identity = 30/60 (50.00%), Postives = 36/60 (60.00%), Query Frame = 1

Query:  109 IHLGDCKEPECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRAR 288
            + L       C+   + GLC GYF RYF+N   G+CE FIYGGC GN+NNF T  EC  R
Sbjct:   63 VSLPSASTGVCAQAPDSGLCFGYFERYFYNFRKGRCEIFIYGGCLGNQNNFLTEKECLQR 122

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Medaka
Match: ENSORLT00000042019.1 (pep primary_assembly:ASM223467v1:12:15740119:15780496:1 gene:ENSORLG00000010354.2 transcript:ENSORLT00000042019.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 63.929 bits (154), Expect = 2.842e-13
Identity = 31/54 (57.41%), Postives = 37/54 (68.52%), Query Frame = 1

Query:  127 KEPECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRAR 288
            K P+  +P + GLC GYF RYF+N   G+CE FIYGGC GN+NNF T  EC  R
Sbjct:   77 KLPQPHIPPDSGLCFGYFERYFYNFRKGRCEIFIYGGCLGNQNNFLTEKECLQR 130

HSP 2 Score: 58.5362 bits (140), Expect = 2.609e-11
Identity = 28/47 (59.57%), Postives = 33/47 (70.21%), Query Frame = 1

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIEC 279
            C+   + GLC GYF RYF+N   G+CE FIYGGC GN+NNF T  EC
Sbjct:   25 CAQAPDSGLCFGYFERYFYNFRKGRCEIFIYGGCLGNQNNFLTEKEC 71

HSP 3 Score: 50.447 bits (119), Expect = 2.034e-8
Identity = 26/51 (50.98%), Postives = 32/51 (62.75%), Query Frame = 1

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
            C+L  + G C  Y  RYF+N +  +CE FIYG C GN+NNF T  EC  RC
Sbjct:  133 CTLDPDPGPCECYSERYFYNFKKRRCEIFIYGCCNGNQNNFETEQECLRRC 183

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Medaka
Match: APP (amyloid-beta A4 protein [Source:NCBI gene;Acc:101162104])

HSP 1 Score: 63.929 bits (154), Expect = 6.543e-13
Identity = 25/51 (49.02%), Postives = 32/51 (62.75%), Query Frame = 1

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
            C    E G CR   PR+FF+ E G+C +FIYGGC GN+NNF +   C + C
Sbjct:  330 CWADAETGPCRALLPRWFFDREEGRCVQFIYGGCGGNRNNFESEEYCMSVC 380

[Close]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Medaka
Match: spint1a (kunitz-type protease inhibitor 1 [Source:NCBI gene;Acc:101175207])

HSP 1 Score: 63.1586 bits (152), Expect = 1.083e-12
Identity = 27/51 (52.94%), Postives = 36/51 (70.59%), Query Frame = 1

Query:  139 CSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
            C +PK+VG CRG FPR+++N  + KCE F +GGC+ NKNN+ T  EC   C
Sbjct:  234 CLVPKKVGPCRGSFPRWYYNAASEKCETFFFGGCRQNKNNYLTEEECAMAC 284

[Close]

BLAST of Kunitz-type protease inhibitor vs. Planmine SMEST
Match: SMESG000013910.1 (SMESG000013910.1)

HSP 1 Score: 139.428 bits (350), Expect = 1.055e-44
Identity = 67/67 (100.00%), Postives = 67/67 (100.00%), Query Frame = 1

Query:   97 FAVAIHLGDCKEPECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 297
            FAVAIHLGDCKEPECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ
Sbjct:    6 FAVAIHLGDCKEPECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 72

[Close]

BLAST of Kunitz-type protease inhibitor vs. Planmine SMEST
Match: SMESG000013915.1 (SMESG000013915.1)

HSP 1 Score: 119.013 bits (297), Expect = 3.237e-36
Identity = 56/60 (93.33%), Postives = 58/60 (96.67%), Query Frame = 1

Query:  118 GDCKEPECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 297
            G  ++PECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ
Sbjct:   38 GRVEKPECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 97

[Close]

BLAST of Kunitz-type protease inhibitor vs. Planmine SMEST
Match: SMESG000037994.1 (SMESG000037994.1)

HSP 1 Score: 82.8037 bits (203), Expect = 3.008e-22
Identity = 37/65 (56.92%), Postives = 46/65 (70.77%), Query Frame = 1

Query:   97 FAVAIHLGDCKEPECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARC 291
            F V   LG+ + PEC+ PK+ G+C  YFPR++FN ++G CE FIYGGCQ N NNF T  EC ARC
Sbjct:   11 FCVIFSLGESRAPECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 75

[Close]

BLAST of Kunitz-type protease inhibitor vs. Planmine SMEST
Match: SMESG000038052.1 (SMESG000038052.1)

HSP 1 Score: 78.9518 bits (193), Expect = 9.401e-21
Identity = 35/67 (52.24%), Postives = 43/67 (64.18%), Query Frame = 1

Query:   97 FAVAIHLGDCKEPECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 297
            F   + L + K PEC+LP E GLC  YF RY F+ + GKC  F+YGGC  N NNF+T  EC  RCE+
Sbjct:   11 FVAVLQLTESKSPECNLPLETGLCEAYFVRYGFDVKLGKCRTFVYGGCHVNDNNFHTRAECEERCEK 77

[Close]

BLAST of Kunitz-type protease inhibitor vs. Planmine SMEST
Match: SMESG000038055.1 (SMESG000038055.1)

HSP 1 Score: 77.0258 bits (188), Expect = 5.110e-20
Identity = 36/67 (53.73%), Postives = 44/67 (65.67%), Query Frame = 1

Query:   97 FAVAIHLGDCKEPECSLPKEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ 297
            F  A+ L + K PEC+L  E GLCR YF RY F+ + GKC  F+YGGC  N NNF+T  EC  RCE+
Sbjct:   11 FVTALQLIEGKAPECNLSLETGLCRAYFVRYGFDVKLGKCRTFVYGGCPVNDNNFHTRAECEERCEK 77

The following BLAST results are available for this feature:

BLAST of Kunitz-type protease inhibitor vs. Ensembl Human
BLAST of Kunitz-type protease inhibitor vs. Ensembl Celegans
BLAST of Kunitz-type protease inhibitor vs. Ensembl Fly
BLAST of Kunitz-type protease inhibitor vs. Ensembl Zebrafish
BLAST of Kunitz-type protease inhibitor vs. Ensembl Xenopus
BLAST of Kunitz-type protease inhibitor vs. Ensembl Mouse
BLAST of Kunitz-type protease inhibitor vs. UniProt/SwissProt
BLAST of Kunitz-type protease inhibitor vs. TrEMBL
BLAST of Kunitz-type protease inhibitor vs. Ensembl Cavefish
BLAST of Kunitz-type protease inhibitor vs. Ensembl Sea Lamprey
BLAST of Kunitz-type protease inhibitor vs. Ensembl Yeast
BLAST of Kunitz-type protease inhibitor vs. Ensembl Nematostella
BLAST of Kunitz-type protease inhibitor vs. Ensembl Medaka
BLAST of Kunitz-type protease inhibitor vs. Planmine SMEST

BLAST of Kunitz-type protease inhibitor vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
TFPI	5.288e-13	54.72	tissue factor pathway inhibitor [Source:HGNC Symbo...	[more]
TFPI	5.288e-13	54.72	tissue factor pathway inhibitor [Source:HGNC Symbo...	[more]
TFPI	7.146e-13	54.72	tissue factor pathway inhibitor [Source:HGNC Symbo...	[more]
TFPI	1.610e-12	54.72	tissue factor pathway inhibitor [Source:HGNC Symbo...	[more]
TFPI	1.610e-12	54.72	tissue factor pathway inhibitor [Source:HGNC Symbo...	[more]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
mlt-11	1.381e-13	39.19	pep chromosome:WBcel235:V:20667209:20678513:1 gene...	[more]
mlt-11	1.437e-13	39.19	pep chromosome:WBcel235:V:20667211:20678513:1 gene...	[more]
mlt-11	1.451e-13	39.19	pep chromosome:WBcel235:V:20667211:20678513:1 gene...	[more]
mlt-11	1.563e-13	39.19	pep chromosome:WBcel235:V:20667211:20678513:1 gene...	[more]
mlt-11	1.606e-13	39.19	pep chromosome:WBcel235:V:20667209:20678513:1 gene...	[more]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
CG3604	3.240e-13	50.00	gene:FBgn0031562 transcript:FBtr0077545	[more]
CG3604	3.240e-13	50.00	gene:FBgn0031562 transcript:FBtr0346581	[more]
CG15418	4.442e-13	54.55	gene:FBgn0031554 transcript:FBtr0077556	[more]
CG15418	4.442e-13	54.55	gene:FBgn0031554 transcript:FBtr0446100	[more]
IM33	5.742e-11	44.29	gene:FBgn0031561 transcript:FBtr0077546	[more]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
spint2	1.653e-12	52.94	serine peptidase inhibitor, Kunitz type, 2 [Source...	[more]
spint2	1.653e-12	52.94	serine peptidase inhibitor, Kunitz type, 2 [Source...	[more]
wfikkn1	2.408e-12	54.90	WAP, follistatin/kazal, immunoglobulin, kunitz and...	[more]
aplp2	3.753e-12	46.43	amyloid beta (A4) precursor-like protein 2 [Source...	[more]
aplp2	3.831e-12	46.43	amyloid beta (A4) precursor-like protein 2 [Source...	[more]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
itch	1.843e-11	46.30	itchy E3 ubiquitin protein ligase [Source:Xenbase;...	[more]
itch	1.845e-11	46.30	itchy E3 ubiquitin protein ligase [Source:Xenbase;...	[more]
itch	1.845e-11	46.30	itchy E3 ubiquitin protein ligase [Source:Xenbase;...	[more]
rlbp1	2.561e-11	49.09	retinaldehyde binding protein 1 [Source:Xenbase;Ac...	[more]
PAPLN	2.581e-11	49.06	papilin, proteoglycan-like sulfated glycoprotein [...	[more]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Spint3	2.668e-15	54.72	serine peptidase inhibitor, Kunitz type, 3 [Source...	[more]
Eppin	9.164e-15	54.72	epididymal peptidase inhibitor [Source:MGI Symbol;...	[more]
Tfpi	2.329e-14	54.72	tissue factor pathway inhibitor [Source:MGI Symbol...	[more]
Tfpi	2.329e-14	54.72	tissue factor pathway inhibitor [Source:MGI Symbol...	[more]
Tfpi	2.329e-14	54.72	tissue factor pathway inhibitor [Source:MGI Symbol...	[more]

BLAST of Kunitz-type protease inhibitor vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|P0DMW6\|VKT3A_ACTEQ	8.397e-19	64.15	PI-actitoxin-Aeq3a OS=Actinia equina OX=6106 PE=1 ...	[more]
sp\|P0DMW7\|VKT3B_ACTEQ	2.451e-18	62.26	PI-actitoxin-Aeq3b OS=Actinia equina OX=6106 PE=1 ...	[more]
sp\|P0DJ50\|VKT31_MESMA	1.370e-17	43.94	Kunitz-type serine protease inhibitor BmKTT-2 OS=M...	[more]
sp\|P0DMX0\|VKT3_ANTAF	3.468e-17	66.67	PI-actitoxin-Axm2b OS=Anthopleura aff. xanthogramm...	[more]
sp\|B1B5I8\|VKT3_STIHA	2.902e-16	64.71	KappaPI-stichotoxin-Shd2a OS=Stichodactyla haddoni...	[more]

BLAST of Kunitz-type protease inhibitor vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
I1ZII0	3.394e-16	55.93	Serine protease inhibitor-1 (Fragment) OS=Schmidte...	[more]
C8YJ95	6.080e-16	50.77	Serine protease inhibitor 3 OS=Tabanus yao OX=4855...	[more]
C1IBY4	8.718e-16	50.77	Tabserpin OS=Tabanus yao OX=485572 PE=2 SV=1	[more]
A0A1V0FWP9	3.327e-15	60.78	Venom kunitz type-like peptide Vf1 (Fragment) OS=V...	[more]
A7T2J6	3.391e-15	62.75	Predicted protein OS=Nematostella vectensis OX=453...	[more]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
lrp11	2.812e-13	47.17	LDL receptor related protein 11 [Source:NCBI gene;...	[more]
lrp11	6.277e-13	47.17	LDL receptor related protein 11 [Source:NCBI gene;...	[more]
aplp2	1.610e-12	49.06	amyloid beta precursor like protein 2 [Source:NCBI...	[more]
aplp2	1.743e-12	49.06	amyloid beta precursor like protein 2 [Source:NCBI...	[more]
aplp2	2.328e-12	49.06	amyloid beta precursor like protein 2 [Source:NCBI...	[more]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
tfpi2	2.985e-16	61.54	tissue factor pathway inhibitor 2 [Source:ZFIN;Acc...	[more]
ENSPMAT00000005038.1	1.104e-12	50.88	pep scaffold:Pmarinus_7.0:GL481015:31246:35903:1 g...	[more]
ENSPMAT00000005043.1	2.342e-12	54.90	pep scaffold:Pmarinus_7.0:GL481015:31246:35903:1 g...	[more]
ENSPMAT00000009465.1	3.921e-10	47.06	pep scaffold:Pmarinus_7.0:GL478507:22936:25713:-1 ...	[more]
WFIKKN1	3.326e-9	43.14	WAP, follistatin/kazal, immunoglobulin, kunitz and...	[more]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Kunitz-type protease inhibitor vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO29819	4.690e-19	62.75	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO41696	5.908e-16	53.85	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO26263	5.908e-16	53.85	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO49645	1.870e-14	49.12	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO31760	1.260e-13	52.94	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Kunitz-type protease inhibitor vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
lrp11	1.040e-13	47.17	low-density lipoprotein receptor-related protein 1...	[more]
ENSORLT00000012975.2	1.371e-13	58.82	pep primary_assembly:ASM223467v1:12:15740273:15760...	[more]
ENSORLT00000042019.1	2.842e-13	57.41	pep primary_assembly:ASM223467v1:12:15740119:15780...	[more]
APP	6.543e-13	49.02	amyloid-beta A4 protein [Source:NCBI gene;Acc:1011...	[more]
spint1a	1.083e-12	52.94	kunitz-type protease inhibitor 1 [Source:NCBI gene...	[more]

BLAST of Kunitz-type protease inhibitor vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000013910.1	1.055e-44	100.00	SMESG000013910.1	[more]
SMESG000013915.1	3.237e-36	93.33	SMESG000013915.1	[more]
SMESG000037994.1	3.008e-22	56.92	SMESG000037994.1	[more]
SMESG000038052.1	9.401e-21	52.24	SMESG000038052.1	[more]
SMESG000038055.1	5.110e-20	53.73	SMESG000038055.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30020210 ID=SMED30020210|Name=Kunitz-type protease inhibitor|organism=Schmidtea mediterranea sexual|type=transcript|length=313bp
CGAAACCAGATAAAGTTCCGACAAAAACAACAAATAATAATAATAATAAT
AATAACAATAATAATAATGAATTCGATAATCATGTTCTCAGTTATATTTG
CCGTTGCTATTCATTTGGGTGATTGTAAAGAACCAGAATGCAGTCTTCCT
AAAGAAGTCGGTCTGTGCAGAGGATATTTCCCAAGGTATTTTTTCAATGA
AGAAACGGGAAAATGTGAGAAATTCATTTATGGTGGATGCCAAGGAAACA
AAAATAATTTCTACACTCCAATTGAATGCAGAGCTCGATGCGAGCAATAA
TTACTGAATATTT

protein sequence of SMED30020210-orf-1

>SMED30020210-orf-1 ID=SMED30020210-orf-1|Name=SMED30020210-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=100bp
RNQIKFRQKQQIIIIIIITIIIMNSIIMFSVIFAVAIHLGDCKEPECSLP
KEVGLCRGYFPRYFFNEETGKCEKFIYGGCQGNKNNFYTPIECRARCEQ*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000067	goblet cell
PLANA:0000419	prepharyngeal region
PLANA:0000421	tail
PLANA:0002075	pigment cell

Vocabulary: **INTERPRO**
Term	Definition
IPR036880	Kunitz_BPTI_sf
IPR002223	Kunitz_BPTI
IPR020901	Prtase_inh_Kunz-CS

Vocabulary: **molecular function**
Term	Definition
GO:0004867	serine-type endopeptidase inhibitor activity
GO:0008233	peptidase activity

Vocabulary: **biological process**
Term	Definition
GO:0006508	proteolysis
GO:0010951	negative regulation of endopeptidase activity

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR002223	Pancreatic trypsin inhibitor Kunitz domain	PRINTS	PR00759	BASICPTASE	coord: 50..60 score: 63.89 coord: 22..36 score: 35.27 coord: 60..75 score: 47.83
IPR002223	Pancreatic trypsin inhibitor Kunitz domain	SMART	SM00131	KU_2	coord: 23..76 e-value: 4.0E-23 score: 92.8
IPR002223	Pancreatic trypsin inhibitor Kunitz domain	PFAM	PF00014	Kunitz_BPTI	coord: 25..76 e-value: 1.8E-19 score: 69.7
IPR002223	Pancreatic trypsin inhibitor Kunitz domain	PROSITE	PS50279	BPTI_KUNITZ_2	coord: 25..75 score: 15.437
IPR002223	Pancreatic trypsin inhibitor Kunitz domain	CDD	cd00109	KU	coord: 25..75 e-value: 8.34499E-22 score: 77.6754
IPR036880	Pancreatic trypsin inhibitor Kunitz domain superfamily	GENE3D	G3DSA:4.10.410.10		coord: 21..77 e-value: 2.9E-23 score: 83.4
IPR036880	Pancreatic trypsin inhibitor Kunitz domain superfamily	SUPERFAMILY	SSF57362	BPTI-like	coord: 20..76
None	No IPR available	PANTHER	PTHR10083	KUNITZ-TYPE PROTEASE INHIBITOR-RELATED	coord: 18..75
None	No IPR available	PANTHER	PTHR10083:SF322	GEO10309P1	coord: 18..75
None	No IPR available	SIGNALP_EUK	SignalP-noTM	SignalP-noTM	coord: 1..20 score: 0.771
IPR020901	Proteinase inhibitor I2, Kunitz, conserved site	PROSITE	PS00280	BPTI_KUNITZ_1	coord: 53..71

Main menu

Kunitz-type protease inhibitor

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 5

Owlery

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