Membrane-bound transcription factor site-2 protease

Overview
NameMembrane-bound transcription factor site-2 protease
Smed IDSMED30020064
Length (bp)1987
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Membrane-bound transcription factor site-2 protease (SMED30020064) t-SNE clustered cells

Violin plots show distribution of expression levels for Membrane-bound transcription factor site-2 protease (SMED30020064) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Membrane-bound transcription factor site-2 protease (SMED30020064) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Membrane-bound transcription factor site-2 protease (SMED30020064) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30020064

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 16

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
gutSMED30020064h1SMcG0010144 Contig4698newmark_estsPMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
gutSMED30020064h1SMcG0010144 Contig4698uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
intestinal phagocyteSMED30020064h1SMcG0010144 Contig4698newmark_estsPMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30020064h1SMcG0010144 Contig4698uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
central nervous systemSMED30020064h1SMcG0010144 Contig4698newmark_estsPMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
central nervous systemSMED30020064h1SMcG0010144 Contig4698uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
gutSMED30020064h1SMcG0018295 Contig4698newmark_estsPMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
gutSMED30020064h1SMcG0018295 Contig4698uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
intestinal phagocyteSMED30020064h1SMcG0018295 Contig4698newmark_estsPMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30020064h1SMcG0018295 Contig4698uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
central nervous systemSMED30020064h1SMcG0018295 Contig4698newmark_estsPMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
central nervous systemSMED30020064h1SMcG0018295 Contig4698uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
Smed sexual biotypeSMED30020064h1SMcG0018295 Contig38612uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30020064h1SMcG0018295 Contig38612newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30020064h1SMcG0018294 Contig38612uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30020064h1SMcG0018294 Contig38612newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Membrane-bound transcription factor site-2 protease vs. Ensembl Human
Match: MBTPS2 (membrane bound transcription factor peptidase, site 2 [Source:HGNC Symbol;Acc:HGNC:15455])

HSP 1 Score: 255.758 bits (652), Expect = 1.406e-76
Identity = 165/515 (32.04%), Postives = 281/515 (54.56%), Query Frame = 3 
Query:  168 YVLDLTLKAHHKTQERYLIWYLNTGISFELLRIKWFTKRFNKYFQILGNLTWFPWKLWFSLGVVVSFFAIIFGXXXXXXXXXNTVSQRVVE-------------------------------HEVLTPVVPGINVPFSDAVYLLLAIIFAAVLHELGHALAATKEKVRVDXXXXXXXXXXPGAYTNINSNDLDNLEPKRKLRIFAAGNWHNTVLLTVGFCIMKLLPILLLPFYRTGDGIAVSYLSQNSVLTGKLGLYQGDVITKVNNCPINSQTDWFNCMQRIQHDSESLNSGYCMPLSRIRQLDISSGFKTRTVWGNIDCCSNQTRSHLCFRYSSNYRFSGQIFHGPKYACLPARTVTERNP-CQTNSNCYPQSHRPDLTCVTPSLENSSRLVRLVHSRTSPVLFLGNVNELLQTVIISNYIPRWILIPNNLPLHLETFLMYLITISGALILFNSVPCYMLDGQWIFQAAVELFLSGILPNRNARRKLCSCVTLLGTILIFTNVSMSIFFMIKQ 1616
            Y+ DL LK+    +  Y  W  N G+S     I+W T  FN+ F   G         WF+ G+V    A+     LL   ++ T++Q + +                                +VL  VVPGIN+P +   Y   A++ + V+HE+GH +AA +E+VR +GFG+  F I+PGA+ ++ +  L  + P ++LRIF AG WHN VL  +G   + LLP++LLPFY TG G+ ++ ++++S   G  GL+ GD++T + +CP+ +  DW  C+  I ++ +    GYC+  S ++QL        R + G+ +CC+N + + +CF Y +N       F+   + CLPAR   E    C+TN +C   S      C+ PSLE  +RL+++ H     +L++G+   L  TV I+++IPR+  +  +LP+ +ETF+ YLI++SGAL + N+VPC+ LDGQWI  + ++  L+ ++ + + +  +   + L G++L+  NV++ ++ +  +
Sbjct:   18 YLTDLVLKSSVYFKHSYEDWLENNGLSISPFHIRWQTAVFNRAFYSWGRRKARMLYQWFNFGMVFGVIAMFSSFFLLGKTLMQTLAQMMADSPSSYSSSSSSSSSSSSSSSSSSSSSSSLHNEQVLQVVVPGINLPVNQLTYFFTAVLISGVVHEIGHGIAAIREQVRFNGFGIFLFIIYPGAFVDLFTTHLQLISPVQQLRIFCAGIWHNFVLALLGILALVLLPVILLPFYYTGVGVLITEVAEDSPAIGPRGLFVGDLVTHLQDCPVTNVQDWNECLDTIAYEPQ---IGYCISASTLQQLSFPVRAYKR-LDGSTECCNNHSLTDVCFSYRNN-------FNKRLHTCLPARKAVEATQVCRTNKDCKKSSSS--SFCIIPSLETHTRLIKVKHPPQIDMLYVGHPLHLHYTVSITSFIPRFNFLSIDLPVVVETFVKYLISLSGALAIVNAVPCFALDGQWILNSFLDATLTSVIGDNDVKDLIGFFILLGGSVLLAANVTLGLWMVTAR 519
[Close]
BLAST of Membrane-bound transcription factor site-2 protease vs. Ensembl Human
Match: MBTPS2 (membrane bound transcription factor peptidase, site 2 [Source:HGNC Symbol;Acc:HGNC:15455])

HSP 1 Score: 142.124 bits (357), Expect = 7.491e-37
Identity = 102/316 (32.28%), Postives = 164/316 (51.90%), Query Frame = 3 
Query:  168 YVLDLTLKAHHKTQERYLIWYLNTGISFELLRIKWFTKRFNKYFQILGNLTWFPWKLWFSLGVVVSFFAIIFGXXXXXXXXXNTVSQRVVE-------------------------------HEVLTPVVPGINVPFSDAVYLLLAIIFAAVLHELGHALAATKEKVRVDXXXXXXXXXXPGAYTNINSNDLDNLEPKRKLRIFAAGNWHNTVLLTVGFCIMKLLPILLLPFYRTGDGIAVSYLSQNSVLTGKLGLYQGDVITKVNNCPINSQTDWFNCMQRIQHDSESLNSGYCMPLSRIRQLDISSGFKTRTVW 1022
            Y+ DL LK+    +  Y  W  N G+S     I+W T  FN+ F   G         WF+ G+V    A+     LL   ++ T++Q + +                                +VL  VVPGIN+P +   Y   A++ + V+HE+GH +AA +E+VR +GFG+  F I+PGA+ ++ +  L  + P ++LRIF AG WHN VL  +G   + LLP++LLPFY TG G+ ++ ++++S   G  GL+ GD++T + +CP+ +  DW  C+  I ++ +    GYC+  S ++QL     F  R V+
Sbjct:   18 YLTDLVLKSSVYFKHSYEDWLENNGLSISPFHIRWQTAVFNRAFYSWGRRKARMLYQWFNFGMVFGVIAMFSSFFLLGKTLMQTLAQMMADSPSSYSSSSSSSSSSSSSSSSSSSSSSSLHNEQVLQVVVPGINLPVNQLTYFFTAVLISGVVHEIGHGIAAIREQVRFNGFGIFLFIIYPGAFVDLFTTHLQLISPVQQLRIFCAGIWHNFVLALLGILALVLLPVILLPFYYTGVGVLITEVAEDSPAIGPRGLFVGDLVTHLQDCPVTNVQDWNECLDTIAYEPQ---IGYCISASTLQQLS----FPVRGVY 326
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BLAST of Membrane-bound transcription factor site-2 protease vs. Ensembl Celegans
Match: Y56A3A.2 (pep chromosome:WBcel235:III:11849951:11862249:-1 gene:WBGene00013225.1 transcript:Y56A3A.2.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y56A3A.2)

HSP 1 Score: 192.586 bits (488), Expect = 7.003e-53
Identity = 127/388 (32.73%), Postives = 198/388 (51.03%), Query Frame = 3 
Query:  438 EHEVLTPVVPGINVPFSDAVYLLLAIIFAAVLHELGHALAATKEKVRVDXXXXXXXXXXPGAYTNINSNDLDNLEPKRKLRIFAAGNWHNTVLLTVGFCIMKLLPILLLPFYRTGDGIAVSYLSQNSVLTG-KLGLYQGDVITKVNNCPINSQTDWFNCMQRIQHDSESLNSGYCMPLSRIRQLDISSGFKTRTVWGNIDCCS--NQTRSHLCFRYSSN--------------------------YRFSGQIFHG---------PKYACLPARTVTERNPCQTNSNCY----PQSHRPDLTCVTPSLENSSRLVRL-VHSRTSPVLFLGNVNELLQTVIISNYIPRWILIPNNLPLHLETFLMYLITISGALILFNSVPCYMLDGQWI 1472
            E   L P++PG N+P+      +L +I AAV HELGHA AAT   V V+GFG+    ++PGA+T+I +  L      R+L+IF AG WHN +L  +   +    P++L P    G G++V  +   S L+  + GL  GDV+  V+ C + +  DW+ C++     S+++N+G C+    +   + ++ F  RT    I CC   N T +H+CF+                               R     + G          KY+CL AR V ++  C  +  C     P +H+  + CV P+L N +RLV++ + +R  P+LF+G +NE+L+ V IS++ PR+     +   H E    YL T+S AL LFN++P Y LDGQ+I
Sbjct:  193 EDRGLVPIIPGFNLPWGHIPIFMLVLIVAAVFHELGHAWAATSNGVTVNGFGIFILAVYPGAFTDIEAVTLKRATTFRRLQIFGAGIWHNLLLALLAMAMFHASPVILSPVLANGYGVSVRGVDVRSGLSNPRTGLVAGDVVKSVDECRVETVADWWRCIR----TSKNMNNGRCVDRESV---EAATAFNHRTEADEILCCDEFNVTTAHVCFQREEKASKLSVDTQTRAPQLNALLGLEGGGGGRDDALPYGGVAQPEEKKITKYSCLHARYVVQQALCNASEPCKTEETPAAHQEKI-CVYPALHNGTRLVKIELANRNKPILFVGQLNEMLEMVSISSFTPRFTFASISWLEHFELTAKYLFTLSLALGLFNAMPVYALDGQFI 572
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BLAST of Membrane-bound transcription factor site-2 protease vs. Ensembl Fly
Match: S2P (gene:FBgn0033656 transcript:FBtr0088063)

HSP 1 Score: 177.948 bits (450), Expect = 2.286e-48
Identity = 138/500 (27.60%), Postives = 231/500 (46.20%), Query Frame = 3 
Query:  135 FAFLIMIWSIIYVLDLTLKA-HHKTQERYLIWYLNTGISFELLRIKWFTKRFNKYFQILGNL----TWFPWKLWFSLGVVVSF----------FAIIFGXXXXXXXXXNTVSQRVVEHEVLTPVVPGINVPFSDAVYLLLAIIFAAVLHELGHALAATKEKVRVDXXXXXXXXXXPGAYTNINSNDLDNLEPKRKLRIFAAGNWHNTVLLTVGFCIMKLLPILLLPFYRTGDGIAVSYLSQNSVLTGKLGLYQGDVITKVNNCPINSQTDWFNCMQRIQHDSESLNSGYCMPLSRIRQLDISSGFKTRTVWGNIDCCSNQTRSHLCFRYSSNYRFSGQI-FHGPKYACLPARTVTERNPCQTNSNCYPQSHRPDLTCVTPSLENSSRLVRLVH-----SRTSPVLFLGNVNELLQTVIISNYIPRWILIPNNLPLHLETFLMYLITISGALILFNSVPCYMLDGQWIFQAAVELFLSGILPNRNARRKLCSCVTLLGTIL 1571
            F  L  ++ ++Y  D   K+  H   + +L    NTG+S   + + W T  FN+     G+     T       F++GV+V+F           A IF           +    V     L  ++PG+N+P  +  Y +  ++   V+HE+GHALAA  E V V GFG+ F F  P AYT ++ + L++L   RKLR+  AG WHN V   V + ++  + I + P Y     + V+ L++ S L G+ GL   + IT+VN CP+NS+  W  C+Q    +S  L  GYC+    ++  D SS     ++ G + CC     +  CF    +   +G +    P++ CL  R   E      +S    +       C+ P + N + ++          +  PV+++G+  ++ +TV +S ++PR+ L+    P      L Y +  S  L L N++PC+  DG  I    +  FL G +     R  +   +T +G++L
Sbjct:    7 FIVLASLYGVLYFFDRFFKSCMHYPYDAFL---KNTGLSINFMSLHWHTSAFNRTLLRWGSAGNSCTRRVMITSFNVGVLVTFSLLPIGLILLIATIFSSGEQDSSSSVSSPVGVPVQ--LEILLPGVNLPLEEIGYYITTLVLCLVVHEMGHALAAVMEDVPVTGFGIKFIFCLPLAYTELSHDHLNSLRWFRKLRVLCAGIWHNFVFAGVCYLLISTVGITMSPLYAYNQHVVVTELTRKSPLRGERGLQVDNQITQVNGCPVNSEESWVTCLQ----NSLKLKPGYCVSADFVQLNDESSAISHHSIDGQLQCCDELNPNVSCFEVVEDA--NGDVPVELPQHVCLNVRRTLEEVSEHCSSGVCNEGF-----CLRPLIRNITAIMTFKRQNFRGEKLPPVIYVGHPWDVTRTVEVSAFVPRYSLLKAAWPDAWLLLLKYNVVFSIGLALINAIPCFGFDGAHITSTVIHSFLVGRVDQHAKRDIISLIITSVGSLL 490
[Close]
BLAST of Membrane-bound transcription factor site-2 protease vs. Ensembl Zebrafish
Match: mbtps2 (membrane-bound transcription factor peptidase, site 2 [Source:ZFIN;Acc:ZDB-GENE-030131-6598])

HSP 1 Score: 291.967 bits (746), Expect = 5.941e-91
Identity = 175/494 (35.43%), Postives = 283/494 (57.29%), Query Frame = 3 
Query:  156 WSIIYVLDLTLKAHHKTQERYLIWYLNTGISFELLRIKWFTKRFNKYFQILGNLTWFPWKLWFSLGVVVSFFAIIFGXXXXXXXXXNTVSQRVVE-----HE-VLTPVVPGINVPFSDAVYLLLAIIFAAVLHELGHALAATKEKVRVDXXXXXXXXXXPGAYTNINSNDLDNLEPKRKLRIFAAGNWHNTVLLTVGFCIMKLLPILLLPFYRTGDGIAVSYLSQNSVLTGKLGLYQGDVITKVNNCPINSQTDWFNCMQRIQHDSESLNSGYCMPLSRIRQLDISSGFKTRTVWGNIDCCSNQTRSHLCFRYSSNYRFSGQIFHGPKYACLPAR-TVTERNPCQTNSNCYPQSHRPDLTCVTPSLENSSRLVRLVHSRTSPVLFLGNVNELLQTVIISNYIPRWILIPNNLPLHLETFLMYLITISGALILFNSVPCYMLDGQWIFQAAVELFLSGILPNRNARRKLCSCVTLLGTILIFTNVSMSIFFMIKQ 1616
            W  +Y+ D  L++    + RY  W  + G +     IKW T  FN+ F    +       +WFS G+V    A+   VVLL   ++ T+ Q + +     HE VL  VVPG+N+P S   Y  +AI+ + V+HE GH +AA +E+VR++GFG+  F I+PGA+ ++ +  L+ + P ++LRIF AG WHN +L  V    + LLPI L PFY TG G  V+ + + S  +G  GL+ GD+IT++ +C +    DW +C+Q + H+ +   +GYC+  +++  L  + G   + + G ++CC N + + LCF YS+N            +ACLP R T+     C TN++C  Q+      C+ PSLEN +RL+R+ H   + +LF+G  + L  +V ++N++PR   +  +LP+ LETF  YL+++SGAL + N+VPC+ LDGQW+  A +E  LS ++  RN R  +     L G+ L+  NV++ ++ +  +
Sbjct:   14 WCTVYLADTLLRSSSSVKNRYESWLSSNGFTLSPFHIKWHTGIFNRLFARCAHFNPHFLYIWFSAGMVFGVLAMFGSVVLLSKTLLQTLHQMMADTPDGSHEQVLQVVVPGVNLPVSQLAYFFIAILVSGVIHEFGHGVAALREQVRLNGFGMFMFVIYPGAFVDLFTTHLNLISPVQQLRIFCAGVWHNFMLCVVALSFLFLLPIFLFPFYYTGAGALVTEVVEGSPSSGPRGLFLGDLITQLEDCTVRGVQDWHSCVQHLSHNPQ---TGYCVHTAKL-HLSYTQGRAFKRLDGTMECCGNNSLTDLCFSYSNNVE-------SKLFACLPVRKTIEASRTCHTNTDC--QTDFTPSLCLIPSLENQTRLIRVKHPPQTDMLFVGYSSHLQYSVSLTNFVPRLGFLHPDLPVMLETFCKYLVSLSGALAVVNAVPCFALDGQWMLTAFLEATLSSVIQERNNRELIGFFFLLGGSALLAANVALGLWMVTAR 494
[Close]
BLAST of Membrane-bound transcription factor site-2 protease vs. Ensembl Xenopus
Match: mbtps2 (membrane bound transcription factor peptidase, site 2 [Source:NCBI gene;Acc:549815])

HSP 1 Score: 296.204 bits (757), Expect = 2.303e-92
Identity = 179/496 (36.09%), Postives = 275/496 (55.44%), Query Frame = 3 
Query:  156 WSIIYVLDLTLKAHHKTQERYLIWYLNTGISFELLRIKWFTKRFNKYFQILGNLTWFPWK-----LWFSLGVVVSFFAIIFGXXXXXXXXXNTVSQRVVE------HEVLTPVVPGINVPFSDAVYLLLAIIFAAVLHELGHALAATKEKVRVDXXXXXXXXXXPGAYTNINSNDLDNLEPKRKLRIFAAGNWHNTVLLTVGFCIMKLLPILLLPFYRTGDGIAVSYLSQNSVLTGKLGLYQGDVITKVNNCPINSQTDWFNCMQRIQHDSESLNSGYCMPLSRIRQLDISSGFKTRTVWGNIDCCSNQTRSHLCFRYSSNYRFSGQIFHGPKYACLPAR-TVTERNPCQTNSNCYPQSHRPDLTCVTPSLENSSRLVRLVHSRTSPVLFLGNVNELLQTVIISNYIPRWILIPNNLPLHLETFLMYLITISGALILFNSVPCYMLDGQWIFQAAVELFLSGILPNRNARRKLCSCVTLLGTILIFTNVSMSIFFM 1607
            W  IY+ D  L +    +  Y  W    G+S     I+W T  FN+ F       W  WK     +WF+LGV     A+   + LL   +V T++Q + E        +L  VVPG+N+P S   Y   AI+ + VLHE+GH +AA +E VR +GFG+  F ++PGA+ ++ +  L  + P ++LRIF AG WHN VL  +G  I+  LP LL PFY TG G  V+ + ++S  +G  GL+  D+IT V +C +    DW  C+  I   S+    GYC+  + ++QL   S    R + G+I+CC+N + S +CF Y+SN   S Q     ++ACLPAR ++     C++N +C  Q       C  PS+EN +RL+R+ HS    +LF+G    L   V +S+++PR+  +  +LP+ +ETF  YLI++SGAL + N+VPC+ LDGQWI  + +E  LS ++  +  R  L   + L G+ L+  NV + ++ +
Sbjct:   14 WCAIYLADTFLTSSQSLKNSYEEWLTARGLSISPFHIRWQTTLFNRLF-----YKWGRWKPNFLYIWFTLGVAFGIIAMFGSIFLLGKTLVQTLNQMMAESPASQNDRMLQVVVPGVNLPISQLSYFFSAILISGVLHEVGHGVAAVRESVRFNGFGMFIFIVYPGAFVDLFTTHLQLVSPVQQLRIFCAGVWHNFVLGILGILILVPLPALLFPFYYTGVGALVTEVVEDSPASGPRGLFVQDLITHVQDCQVTGVDDWHTCLTEI---SQMPQIGYCINTATLQQLQFPSRVY-RRLDGSIECCNNNSLSDICFSYNSN---SNQ----QQFACLPARKSIHNSQECRSNIDC--QKTDAASVCAVPSIENQTRLIRVKHSPQLDMLFIGYPVHLQYAVSLSSFVPRYNFLSISLPVVIETFCKYLISLSGALAVINAVPCFALDGQWILNSFIEATLSSVIAEKQNRELLAFFILLAGSALLTANVVLGLWMV 491
[Close]
BLAST of Membrane-bound transcription factor site-2 protease vs. Ensembl Xenopus
Match: mbtps2 (membrane bound transcription factor peptidase, site 2 [Source:NCBI gene;Acc:549815])

HSP 1 Score: 288.115 bits (736), Expect = 1.955e-89
Identity = 174/488 (35.66%), Postives = 272/488 (55.74%), Query Frame = 3 
Query:  180 LTLKAHHKTQERYLIWYLNTGISFELLRIKWFTKRFNKYFQILGNLTWFPWK-----LWFSLGVVVSFFAIIFGXXXXXXXXXNTVSQRVVE------HEVLTPVVPGINVPFSDAVYLLLAIIFAAVLHELGHALAATKEKVRVDXXXXXXXXXXPGAYTNINSNDLDNLEPKRKLRIFAAGNWHNTVLLTVGFCIMKLLPILLLPFYRTGDGIAVSYLSQNSVLTGKLGLYQGDVITKVNNCPINSQTDWFNCMQRIQHDSESLNSGYCMPLSRIRQLDISSGFKTRTVWGNIDCCSNQTRSHLCFRYSSNYRFSGQIFHGPKYACLPAR-TVTERNPCQTNSNCYPQSHRPDLTCVTPSLENSSRLVRLVHSRTSPVLFLGNVNELLQTVIISNYIPRWILIPNNLPLHLETFLMYLITISGALILFNSVPCYMLDGQWIFQAAVELFLSGILPNRNARRKLCSCVTLLGTILIFTNVSMSIFFM 1607
            ++ ++    +  Y  W    G+S     I+W T  FN+ F       W  WK     +WF+LGV     A+   + LL   +V T++Q + E        +L  VVPG+N+P S   Y   AI+ + VLHE+GH +AA +E VR +GFG+  F ++PGA+ ++ +  L  + P ++LRIF AG WHN VL  +G  I+  LP LL PFY TG G  V+ + ++S  +G  GL+  D+IT V +C +    DW  C+  I   S+    GYC+  + ++QL   S    R + G+I+CC+N + S +CF Y+SN   S Q     ++ACLPAR ++     C++N +C  Q       C  PS+EN +RL+R+ HS    +LF+G    L   V +S+++PR+  +  +LP+ +ETF  YLI++SGAL + N+VPC+ LDGQWI  + +E  LS ++  +  R  L   + L G+ L+  NV + ++ +
Sbjct:    6 MSQQSSQSLKNSYEEWLTARGLSISPFHIRWQTTLFNRLF-----YKWGRWKPNFLYIWFTLGVAFGIIAMFGSIFLLGKTLVQTLNQMMAESPASQNDRMLQVVVPGVNLPISQLSYFFSAILISGVLHEVGHGVAAVRESVRFNGFGMFIFIVYPGAFVDLFTTHLQLVSPVQQLRIFCAGVWHNFVLGILGILILVPLPALLFPFYYTGVGALVTEVVEDSPASGPRGLFVQDLITHVQDCQVTGVDDWHTCLTEI---SQMPQIGYCINTATLQQLQFPSRVY-RRLDGSIECCNNNSLSDICFSYNSN---SNQ----QQFACLPARKSIHNSQECRSNIDC--QKTDAASVCAVPSIENQTRLIRVKHSPQLDMLFIGYPVHLQYAVSLSSFVPRYNFLSISLPVVIETFCKYLISLSGALAVINAVPCFALDGQWILNSFIEATLSSVIAEKQNRELLAFFILLAGSALLTANVVLGLWMV 475
[Close]
BLAST of Membrane-bound transcription factor site-2 protease vs. Ensembl Xenopus
Match: mbtps2 (membrane bound transcription factor peptidase, site 2 [Source:NCBI gene;Acc:549815])

HSP 1 Score: 286.96 bits (733), Expect = 6.203e-89
Identity = 174/479 (36.33%), Postives = 268/479 (55.95%), Query Frame = 3 
Query:  207 QERYLIWYLNTGISFELLRIKWFTKRFNKYFQILGNLTWFPWK-----LWFSLGVVVSFFAIIFGXXXXXXXXXNTVSQRVVE------HEVLTPVVPGINVPFSDAVYLLLAIIFAAVLHELGHALAATKEKVRVDXXXXXXXXXXPGAYTNINSNDLDNLEPKRKLRIFAAGNWHNTVLLTVGFCIMKLLPILLLPFYRTGDGIAVSYLSQNSVLTGKLGLYQGDVITKVNNCPINSQTDWFNCMQRIQHDSESLNSGYCMPLSRIRQLDISSGFKTRTVWGNIDCCSNQTRSHLCFRYSSNYRFSGQIFHGPKYACLPAR-TVTERNPCQTNSNCYPQSHRPDLTCVTPSLENSSRLVRLVHSRTSPVLFLGNVNELLQTVIISNYIPRWILIPNNLPLHLETFLMYLITISGALILFNSVPCYMLDGQWIFQAAVELFLSGILPNRNARRKLCSCVTLLGTILIFTNVSMSIFFM 1607
            +  Y  W    G+S     I+W T  FN+ F       W  WK     +WF+LGV     A+   + LL   +V T++Q + E        +L  VVPG+N+P S   Y   AI+ + VLHE+GH +AA +E VR +GFG+  F ++PGA+ ++ +  L  + P ++LRIF AG WHN VL  +G  I+  LP LL PFY TG G  V+ + ++S  +G  GL+  D+IT V +C +    DW  C+  I   S+    GYC+  + ++QL   S    R + G+I+CC+N + S +CF Y+SN   S Q     ++ACLPAR ++     C++N +C  Q       C  PS+EN +RL+R+ HS    +LF+G    L   V +S+++PR+  +  +LP+ +ETF  YLI++SGAL + N+VPC+ LDGQWI  + +E  LS ++  +  R  L   + L G+ L+  NV + ++ +
Sbjct:   18 KNSYEEWLTARGLSISPFHIRWQTTLFNRLF-----YKWGRWKPNFLYIWFTLGVAFGIIAMFGSIFLLGKTLVQTLNQMMAESPASQNDRMLQVVVPGVNLPISQLSYFFSAILISGVLHEVGHGVAAVRESVRFNGFGMFIFIVYPGAFVDLFTTHLQLVSPVQQLRIFCAGVWHNFVLGILGILILVPLPALLFPFYYTGVGALVTEVVEDSPASGPRGLFVQDLITHVQDCQVTGVDDWHTCLTEI---SQMPQIGYCINTATLQQLQFPSRVY-RRLDGSIECCNNNSLSDICFSYNSN---SNQ----QQFACLPARKSIHNSQECRSNIDC--QKTDAASVCAVPSIENQTRLIRVKHSPQLDMLFIGYPVHLQYAVSLSSFVPRYNFLSISLPVVIETFCKYLISLSGALAVINAVPCFALDGQWILNSFIEATLSSVIAEKQNRELLAFFILLAGSALLTANVVLGLWMV 478
[Close]
BLAST of Membrane-bound transcription factor site-2 protease vs. Ensembl Mouse
Match: Mbtps2 (membrane-bound transcription factor peptidase, site 2 [Source:MGI Symbol;Acc:MGI:2444506])

HSP 1 Score: 264.233 bits (674), Expect = 5.475e-80
Identity = 165/515 (32.04%), Postives = 285/515 (55.34%), Query Frame = 3 
Query:  156 WSIIYVLDLTLKAHHKTQERYLIWYLNTGISFELLRIKWFTKRFNKYFQILGNLTWFPWKLWFSLGVVVSFFAIIFGXXXXXXXXXNTVSQRVVE---------------------------HEVLTPVVPGINVPFSDAVYLLLAIIFAAVLHELGHALAATKEKVRVDXXXXXXXXXXPGAYTNINSNDLDNLEPKRKLRIFAAGNWHNTVLLTVGFCIMKLLPILLLPFYRTGDGIAVSYLSQNSVLTGKLGLYQGDVITKVNNCPINSQTDWFNCMQRIQHDSESLNSGYCMPLSRIRQLDISSGFKTRTVWGNIDCCSNQTRSHLCFRYSSNYRFSGQIFHGPKYACLPARTVTERNP-CQTNSNCYPQSHRPDLTCVTPSLENSSRLVRLVHSRTSPVLFLGNVNELLQTVIISNYIPRWILIPNNLPLHLETFLMYLITISGALILFNSVPCYMLDGQWIFQAAVELFLSGILPNRNARRKLCSCVTLLGTILIFTNVSMSIFFMIKQ 1616
            W+ +Y+ DL LK+    +  Y  W  N G+S     I+W T  FN+ F   G         WF+ G+V    A+     LL   ++ T++Q + +                            +VL  VVPGIN+P +   Y   A++ + V+HE+GH +AA +E+VR +GFG+  F I+PGA+ ++ +  L  + P ++LRIF AG WHN VL  +G   + LLP++LLPFY TG G+ ++ ++++S   G  GL+ GD++T + +CP+ +  DW  C+  I ++ +    GYC+  S ++QL        R + G+ +CC+N + + +CF Y +N       F+   + CLPAR   E    C++N +C  +S      C+ PSLE  +RL+++ H     +L++G+   L  TV I+++IPR+  +  +LP+ +ETF+ YLI++SGAL + N+VPC+ LDGQWI  + ++  L+ ++ + + +  +   + L G++L+  NV++ ++ +  +
Sbjct:   14 WTAVYLADLVLKSSVYFKHSYEDWLENNGLSISPFHIRWQTSIFNRAFYSWGRRKARMLYQWFNFGMVFGVIAMFSSFFLLGKTLMQTLAQMMADSPSPYSSSSSSSSSSSSSSSSSSSLHNEQVLQVVVPGINLPVNQLTYFFAAVLISGVVHEIGHGIAAIREQVRFNGFGIFLFIIYPGAFVDLFTTHLQLISPVQQLRIFCAGIWHNFVLALLGILALVLLPVILLPFYYTGVGVLITEVAEDSPAIGPRGLFVGDLVTHLQDCPVTNVQDWNECLDTIAYEPQ---IGYCISASTLQQLSFPVRAYKR-LDGSTECCNNHSLTDVCFSYRNN-------FNKRLHTCLPARKAVEATQVCRSNKDC--KSGASSSFCIVPSLETHTRLIKVKHPPQIDMLYVGHPLHLHYTVSITSFIPRFNFLSIDLPVIVETFVKYLISLSGALAIVNAVPCFALDGQWILNSFLDATLTSVIGDNDVKDLIGFFILLGGSVLLAANVTLGLWMVTAR 515
[Close]
BLAST of Membrane-bound transcription factor site-2 protease vs. Ensembl Mouse
Match: Mbtps2 (membrane-bound transcription factor peptidase, site 2 [Source:MGI Symbol;Acc:MGI:2444506])

HSP 1 Score: 91.2781 bits (225), Expect = 2.576e-20
Identity = 63/206 (30.58%), Postives = 101/206 (49.03%), Query Frame = 3 
Query:  156 WSIIYVLDLTLKAHHKTQERYLIWYLNTGISFELLRIKWFTKRFNKYFQILGNLTWFPWKLWFSLGVVVSFFAIIFGXXXXXXXXXNTVSQRVVE---------------------------HEVLTPVVPGINVPFSDAVYLLLAIIFAAVLHELGHALAATKEKVRVDXXXXXXXXXXPGAYTNINSNDLDNLEPKRKLRIFAA 692
            W+ +Y+ DL LK+    +  Y  W  N G+S     I+W T  FN+ F   G         WF+ G+V    A+     LL   ++ T++Q + +                            +VL  VVPGIN+P +   Y   A++ + V+HE+GH +AA +E+VR +GFG+  F I+PGA+ ++ +  L  + P ++LRIF A
Sbjct:   14 WTAVYLADLVLKSSVYFKHSYEDWLENNGLSISPFHIRWQTSIFNRAFYSWGRRKARMLYQWFNFGMVFGVIAMFSSFFLLGKTLMQTLAQMMADSPSPYSSSSSSSSSSSSSSSSSSSLHNEQVLQVVVPGINLPVNQLTYFFAAVLISGVVHEIGHGIAAIREQVRFNGFGIFLFIIYPGAFVDLFTTHLQLISPVQQLRIFCA 219
[Close]
BLAST of Membrane-bound transcription factor site-2 protease vs. Ensembl Mouse
Match: Mbtps2 (membrane-bound transcription factor peptidase, site 2 [Source:MGI Symbol;Acc:MGI:2444506])

HSP 1 Score: 51.9878 bits (123), Expect = 7.220e-8
Identity = 21/47 (44.68%), Postives = 33/47 (70.21%), Query Frame = 3 
Query:  444 EVLTPVVPGINVPFSDAVYLLLAIIFAAVLHELGHALAATKEKVRVD 584
            +VL  VVPGIN+P +   Y   A++ + V+HE+GH +AA +E+VR +
Sbjct:   58 QVLQVVVPGINLPVNQLTYFFAAVLISGVVHEIGHGIAAIREQVRFN 104
[Close]
BLAST of Membrane-bound transcription factor site-2 protease vs. UniProt/SwissProt
Match: sp|O54862|MBTP2_CRIGR (Membrane-bound transcription factor site-2 protease OS=Cricetulus griseus OX=10029 GN=MBTPS2 PE=2 SV=1)

HSP 1 Score: 264.618 bits (675), Expect = 1.773e-79
Identity = 165/510 (32.35%), Postives = 283/510 (55.49%), Query Frame = 3 
Query:  156 WSIIYVLDLTLKAHHKTQERYLIWYLNTGISFELLRIKWFTKRFNKYFQILGNLTWFPWKLWFSLGVVVSFFAIIFGXXXXXXXXXNTVSQRVVE----------------------HEVLTPVVPGINVPFSDAVYLLLAIIFAAVLHELGHALAATKEKVRVDXXXXXXXXXXPGAYTNINSNDLDNLEPKRKLRIFAAGNWHNTVLLTVGFCIMKLLPILLLPFYRTGDGIAVSYLSQNSVLTGKLGLYQGDVITKVNNCPINSQTDWFNCMQRIQHDSESLNSGYCMPLSRIRQLDISSGFKTRTVWGNIDCCSNQTRSHLCFRYSSNYRFSGQIFHGPKYACLPARTVTERNP-CQTNSNCYPQSHRPDLTCVTPSLENSSRLVRLVHSRTSPVLFLGNVNELLQTVIISNYIPRWILIPNNLPLHLETFLMYLITISGALILFNSVPCYMLDGQWIFQAAVELFLSGILPNRNARRKLCSCVTLLGTILIFTNVSMSIFFMIKQ 1616
            W+ +Y+ DL LK+    +  Y  W    G+S     I+W T  FN+ F   G         WF+ G+V    A+     LL   ++ T++Q + +                       +VL  VVPGIN+P +   Y   A++ + V+HE+GH +AA +E+VR +GFG+  F I+PGA+ ++ +  L  + P ++LRIF AG WHN VL  +G   + LLP++LLPFY TG G+ ++ ++++S   G  GL+ GD++T + +CP+ +  DW  C+  I ++ +    GYC+  S ++QL        R + G+ +CC+N + + +CF Y +N       F+   + CLPAR   E    C+TN +C   S      C+ PSLE  +RL+++ H     +L++G+   L  TV I+++IPR+  +  +LP+ +ETF+ YLI++SGAL + N+VPC+ LDGQWI  + ++  L+ ++ + + +  +   + L G++L+  NV++ ++ +  +
Sbjct:   14 WTAVYLADLVLKSSVYFKHSYEDWLEKNGLSISPFHIRWQTSVFNRAFYSWGRRKARMLYQWFNFGMVFGVIAMFSSFFLLGKTLMQTLAQMMADSPSSSSSSSSSSSSSSSSSIHNEQVLQVVVPGINLPVNQLTYFFAAVLISGVVHEIGHGIAAIREQVRFNGFGIFLFIIYPGAFVDLFTTHLQLISPVQQLRIFCAGIWHNFVLALLGILALVLLPVILLPFYYTGVGVLITEVAEDSPAIGPRGLFVGDLVTHLQDCPVTNVQDWNECLDTIAYEPQ---IGYCISASTLQQLSFPVRAYKR-LDGSTECCNNHSLTDVCFSYRNN-------FNKRLHTCLPARKAVEATQVCRTNKDCKTSSSSS--FCIVPSLETHTRLIKVKHPPQIDMLYVGHPLHLHYTVSITSFIPRFNFLSIDLPVIVETFVKYLISLSGALAIVNAVPCFALDGQWILNSFLDATLTSVIGDNDVKDLIGFFILLGGSVLLAANVTLGLWMVTAR 510
[Close]
BLAST of Membrane-bound transcription factor site-2 protease vs. UniProt/SwissProt
Match: sp|Q8CHX6|MBTP2_MOUSE (Membrane-bound transcription factor site-2 protease OS=Mus musculus OX=10090 GN=Mbtps2 PE=2 SV=1)

HSP 1 Score: 264.233 bits (674), Expect = 3.830e-79
Identity = 165/515 (32.04%), Postives = 285/515 (55.34%), Query Frame = 3 
Query:  156 WSIIYVLDLTLKAHHKTQERYLIWYLNTGISFELLRIKWFTKRFNKYFQILGNLTWFPWKLWFSLGVVVSFFAIIFGXXXXXXXXXNTVSQRVVE---------------------------HEVLTPVVPGINVPFSDAVYLLLAIIFAAVLHELGHALAATKEKVRVDXXXXXXXXXXPGAYTNINSNDLDNLEPKRKLRIFAAGNWHNTVLLTVGFCIMKLLPILLLPFYRTGDGIAVSYLSQNSVLTGKLGLYQGDVITKVNNCPINSQTDWFNCMQRIQHDSESLNSGYCMPLSRIRQLDISSGFKTRTVWGNIDCCSNQTRSHLCFRYSSNYRFSGQIFHGPKYACLPARTVTERNP-CQTNSNCYPQSHRPDLTCVTPSLENSSRLVRLVHSRTSPVLFLGNVNELLQTVIISNYIPRWILIPNNLPLHLETFLMYLITISGALILFNSVPCYMLDGQWIFQAAVELFLSGILPNRNARRKLCSCVTLLGTILIFTNVSMSIFFMIKQ 1616
            W+ +Y+ DL LK+    +  Y  W  N G+S     I+W T  FN+ F   G         WF+ G+V    A+     LL   ++ T++Q + +                            +VL  VVPGIN+P +   Y   A++ + V+HE+GH +AA +E+VR +GFG+  F I+PGA+ ++ +  L  + P ++LRIF AG WHN VL  +G   + LLP++LLPFY TG G+ ++ ++++S   G  GL+ GD++T + +CP+ +  DW  C+  I ++ +    GYC+  S ++QL        R + G+ +CC+N + + +CF Y +N       F+   + CLPAR   E    C++N +C  +S      C+ PSLE  +RL+++ H     +L++G+   L  TV I+++IPR+  +  +LP+ +ETF+ YLI++SGAL + N+VPC+ LDGQWI  + ++  L+ ++ + + +  +   + L G++L+  NV++ ++ +  +
Sbjct:   14 WTAVYLADLVLKSSVYFKHSYEDWLENNGLSISPFHIRWQTSIFNRAFYSWGRRKARMLYQWFNFGMVFGVIAMFSSFFLLGKTLMQTLAQMMADSPSPYSSSSSSSSSSSSSSSSSSSLHNEQVLQVVVPGINLPVNQLTYFFAAVLISGVVHEIGHGIAAIREQVRFNGFGIFLFIIYPGAFVDLFTTHLQLISPVQQLRIFCAGIWHNFVLALLGILALVLLPVILLPFYYTGVGVLITEVAEDSPAIGPRGLFVGDLVTHLQDCPVTNVQDWNECLDTIAYEPQ---IGYCISASTLQQLSFPVRAYKR-LDGSTECCNNHSLTDVCFSYRNN-------FNKRLHTCLPARKAVEATQVCRSNKDC--KSGASSSFCIVPSLETHTRLIKVKHPPQIDMLYVGHPLHLHYTVSITSFIPRFNFLSIDLPVIVETFVKYLISLSGALAIVNAVPCFALDGQWILNSFLDATLTSVIGDNDVKDLIGFFILLGGSVLLAANVTLGLWMVTAR 515
[Close]
BLAST of Membrane-bound transcription factor site-2 protease vs. UniProt/SwissProt
Match: sp|Q0III2|MBTP2_BOVIN (Membrane-bound transcription factor site-2 protease OS=Bos taurus OX=9913 GN=MBTPS2 PE=2 SV=1)

HSP 1 Score: 262.692 bits (670), Expect = 1.286e-78
Identity = 166/516 (32.17%), Postives = 283/516 (54.84%), Query Frame = 3 
Query:  156 WSIIYVLDLTLKAHHKTQERYLIWYLNTGISFELLRIKWFTKRFNKYFQILGNLTWFPWKLWFSLGVVVSFFAIIFGXXXXXXXXXNTVSQRVVE----------------------------HEVLTPVVPGINVPFSDAVYLLLAIIFAAVLHELGHALAATKEKVRVDXXXXXXXXXXPGAYTNINSNDLDNLEPKRKLRIFAAGNWHNTVLLTVGFCIMKLLPILLLPFYRTGDGIAVSYLSQNSVLTGKLGLYQGDVITKVNNCPINSQTDWFNCMQRIQHDSESLNSGYCMPLSRIRQLDISSGFKTRTVWGNIDCCSNQTRSHLCFRYSSNYRFSGQIFHGPKYACLPARTVTERNP-CQTNSNCYPQSHRPDLTCVTPSLENSSRLVRLVHSRTSPVLFLGNVNELLQTVIISNYIPRWILIPNNLPLHLETFLMYLITISGALILFNSVPCYMLDGQWIFQAAVELFLSGILPNRNARRKLCSCVTLLGTILIFTNVSMSIFFMIKQ 1616
            W+ +Y+ DL LK+    +  Y  W  N G+S     I+W T  FN+ F   G         WF+ G+V    A+     LL   ++ T+ Q + +                             +VL  VVPGIN+P +   Y   A++ + V+HE+GH +AA +E+VR +GFG+  F I+PGA+ ++ +  L  + P ++LRIF AG WHN +L  +G   + LLP++LLPFY TG G+ ++ ++++S   G  GL+ GD++T + +CP+ +  DW  C+  I ++ +    GYC+  S ++QL        R + G+ +CC+N + + +CF Y +N       F+   + CLPAR   E    C+TN +C   S      C+ PSLE  +RL+++ H     +L++G+   L  TV I+++IPR+  +  +LP+ +ETF+ YLI++SGAL + N+VPC+ LDGQWI  + ++  L+ ++ + + +  +   + L G+IL+  NV++ ++ +  +
Sbjct:   14 WTAVYLTDLVLKSSVYFKHSYEDWLENNGLSISPFHIRWQTAVFNRAFYSWGRRKARMLYQWFNFGMVFGVIAMFSSFFLLGKTLIQTLGQMMADSSYSSSSSSSSHSSSSSSSSSSSSSLYNEQVLQVVVPGINLPVNQLTYFFAAVLISGVVHEIGHGIAAIREQVRFNGFGIFLFIIYPGAFVDLFTTHLQLISPVQQLRIFCAGIWHNFILALLGILALILLPVILLPFYYTGVGVLITEVAEDSPAIGPRGLFVGDLVTHLQDCPVTNVQDWNECLDTITYEPQ---IGYCISASTLQQLSFPVRAYKR-LDGSTECCNNHSLTDVCFSYRNN-------FNKRLHTCLPARKAVEATQVCRTNKDCKKSSSS--SFCIIPSLETHTRLIKVKHPPQIDMLYVGHPLHLHYTVSITSFIPRFKFLSIDLPVVVETFVKYLISLSGALAIVNAVPCFALDGQWILNSFLDATLTSVIGDNDVKDLIGFFILLGGSILLAANVALGLWMVTAR 516
[Close]
BLAST of Membrane-bound transcription factor site-2 protease vs. UniProt/SwissProt
Match: sp|O43462|MBTP2_HUMAN (Membrane-bound transcription factor site-2 protease OS=Homo sapiens OX=9606 GN=MBTPS2 PE=1 SV=1)

HSP 1 Score: 255.758 bits (652), Expect = 6.753e-76
Identity = 165/515 (32.04%), Postives = 281/515 (54.56%), Query Frame = 3 
Query:  168 YVLDLTLKAHHKTQERYLIWYLNTGISFELLRIKWFTKRFNKYFQILGNLTWFPWKLWFSLGVVVSFFAIIFGXXXXXXXXXNTVSQRVVE-------------------------------HEVLTPVVPGINVPFSDAVYLLLAIIFAAVLHELGHALAATKEKVRVDXXXXXXXXXXPGAYTNINSNDLDNLEPKRKLRIFAAGNWHNTVLLTVGFCIMKLLPILLLPFYRTGDGIAVSYLSQNSVLTGKLGLYQGDVITKVNNCPINSQTDWFNCMQRIQHDSESLNSGYCMPLSRIRQLDISSGFKTRTVWGNIDCCSNQTRSHLCFRYSSNYRFSGQIFHGPKYACLPARTVTERNP-CQTNSNCYPQSHRPDLTCVTPSLENSSRLVRLVHSRTSPVLFLGNVNELLQTVIISNYIPRWILIPNNLPLHLETFLMYLITISGALILFNSVPCYMLDGQWIFQAAVELFLSGILPNRNARRKLCSCVTLLGTILIFTNVSMSIFFMIKQ 1616
            Y+ DL LK+    +  Y  W  N G+S     I+W T  FN+ F   G         WF+ G+V    A+     LL   ++ T++Q + +                                +VL  VVPGIN+P +   Y   A++ + V+HE+GH +AA +E+VR +GFG+  F I+PGA+ ++ +  L  + P ++LRIF AG WHN VL  +G   + LLP++LLPFY TG G+ ++ ++++S   G  GL+ GD++T + +CP+ +  DW  C+  I ++ +    GYC+  S ++QL        R + G+ +CC+N + + +CF Y +N       F+   + CLPAR   E    C+TN +C   S      C+ PSLE  +RL+++ H     +L++G+   L  TV I+++IPR+  +  +LP+ +ETF+ YLI++SGAL + N+VPC+ LDGQWI  + ++  L+ ++ + + +  +   + L G++L+  NV++ ++ +  +
Sbjct:   18 YLTDLVLKSSVYFKHSYEDWLENNGLSISPFHIRWQTAVFNRAFYSWGRRKARMLYQWFNFGMVFGVIAMFSSFFLLGKTLMQTLAQMMADSPSSYSSSSSSSSSSSSSSSSSSSSSSSLHNEQVLQVVVPGINLPVNQLTYFFTAVLISGVVHEIGHGIAAIREQVRFNGFGIFLFIIYPGAFVDLFTTHLQLISPVQQLRIFCAGIWHNFVLALLGILALVLLPVILLPFYYTGVGVLITEVAEDSPAIGPRGLFVGDLVTHLQDCPVTNVQDWNECLDTIAYEPQ---IGYCISASTLQQLSFPVRAYKR-LDGSTECCNNHSLTDVCFSYRNN-------FNKRLHTCLPARKAVEATQVCRTNKDCKKSSSS--SFCIIPSLETHTRLIKVKHPPQIDMLYVGHPLHLHYTVSITSFIPRFNFLSIDLPVVVETFVKYLISLSGALAIVNAVPCFALDGQWILNSFLDATLTSVIGDNDVKDLIGFFILLGGSVLLAANVTLGLWMVTAR 519
[Close]
BLAST of Membrane-bound transcription factor site-2 protease vs. UniProt/SwissProt
Match: sp|Q5RAC8|MBTP2_PONAB (Membrane-bound transcription factor site-2 protease OS=Pongo abelii OX=9601 GN=MBTPS2 PE=2 SV=1)

HSP 1 Score: 253.062 bits (645), Expect = 5.921e-75
Identity = 164/517 (31.72%), Postives = 281/517 (54.35%), Query Frame = 3 
Query:  168 YVLDLTLKAHHKTQERYLIWYLNTGISFELLRIKWFTKRFNKYFQILGNLTWFPWKLWFSLGVVVSFFAIIFGXXXXXXXXXNTVSQRVVE---------------------------------HEVLTPVVPGINVPFSDAVYLLLAIIFAAVLHELGHALAATKEKVRVDXXXXXXXXXXPGAYTNINSNDLDNLEPKRKLRIFAAGNWHNTVLLTVGFCIMKLLPILLLPFYRTGDGIAVSYLSQNSVLTGKLGLYQGDVITKVNNCPINSQTDWFNCMQRIQHDSESLNSGYCMPLSRIRQLDISSGFKTRTVWGNIDCCSNQTRSHLCFRYSSNYRFSGQIFHGPKYACLPARTVTERNP-CQTNSNCYPQSHRPDLTCVTPSLENSSRLVRLVHSRTSPVLFLGNVNELLQTVIISNYIPRWILIPNNLPLHLETFLMYLITISGALILFNSVPCYMLDGQWIFQAAVELFLSGILPNRNARRKLCSCVTLLGTILIFTNVSMSIFFMIKQ 1616
            Y+ DL LK+    +  Y  W  + G+S     I+W T  FN+ F   G         WF+ G+V    A+     LL   ++ T++Q + +                                  +VL  VVPGIN+P +   Y   A++ + V+HE+GH +AA +E+VR +GFG+  F I+PGA+ ++ +  L  + P ++LRIF AG WHN VL  +G   + LLP++LLPFY TG G+ ++ ++++S   G  GL+ GD++T + +CP+ +  DW  C+  I ++ +    GYC+  S ++QL        R + G+ +CC+N + + +CF Y +N       F+   + CLPAR   E    C+TN +C   S      C+ PSLE  +RL+++ H     +L++G+   L  TV I+++IPR+  +  +LP+ +ETF+ YLI++SGAL + N+VPC+ LDGQWI  + ++  L+ ++ + + +  +   + L G++L+  NV++ ++ +  +
Sbjct:   18 YLTDLVLKSSVYFKHSYEDWLESNGLSISPFHIRWQTAVFNRAFYSWGRRKARMLYQWFNFGMVFGVIAMFSSFFLLGKTLMQTLAQMMADSPSSYSSSSSSSSSSSSSSSSSSSSSSSSSLHNEQVLQVVVPGINLPVNQLTYFFAAVLISGVVHEIGHGIAAIREQVRFNGFGIFLFIIYPGAFVDLFTTHLQLISPVQQLRIFCAGIWHNFVLALLGILALVLLPVILLPFYYTGVGVLITEVAEDSPAIGPRGLFVGDLVTHLQDCPVTNVQDWNECLDTIAYEPQ---IGYCISASTLQQLSFPVRAYKR-LDGSTECCNNHSLTDVCFSYRNN-------FNKRLHTCLPARKAVEATQVCRTNKDCKKSSSS--SFCIIPSLETHTRLIKVKHPPQIDMLYVGHPLHLHYTVSITSFIPRFNFLSIDLPVVVETFVKYLISLSGALAIVNAVPCFALDGQWILNSFLDATLTSVIGDNDVKDLIGFFILLGGSVLLAANVTLGLWMVTAR 521
[Close]
BLAST of Membrane-bound transcription factor site-2 protease vs. TrEMBL
Match: A0A0X3PPF0 (Membrane-bound transcription factor site-2 protease OS=Schistocephalus solidus OX=70667 GN=MBTP2 PE=4 SV=1)

HSP 1 Score: 372.089 bits (954), Expect = 1.477e-117
Identity = 209/538 (38.85%), Postives = 318/538 (59.11%), Query Frame = 3 
Query:  135 FAFLIMIWSIIYVLDLTLKAHHKTQERYLIWYLNTGISFELLRIKWFTKRFNKYFQILGNLTWFPWKLWFSLGVVVSFFAIIFGXXXXXXXXXNTVSQRVVEHEVLTPVVPGINVPFSDAVYLLLAIIFAAVLHELGHALAATKEKVRVDXXXXXXXXXXPGAYTNINSNDLDNLEPKRKLRIFAAGNWHNTVLLTVGFCIMKLLPILLLPFYRTGDGIAVSYLSQNSVLTGKLGLYQGDVITKVNNCPINSQTDWFNCMQRIQHDSESLNSGYCMPLSRIRQLDIS-----------------------------------SGFKTRTVWGNIDCCSNQTRS-HLCFRYSSNYRFSGQIFHGPKYACLPARTVTERNPCQTNSNCYPQSHRPDL--TCVTPS-LENSSRLVRLVH--SRTSPVLFLGNVNELLQTVIISNYIPRWI-LIPNNLPLHLETFLMYLITISGALILFNSVPCYMLDGQWIFQAAVELFLSGILPNRNARRKLCSCVTLLGTILIFTNVSMSIFFMIKQYS 1622
             ++    W++ Y++D  L  H  T++RYL     +GIS ++L+ ++FT++ N +FQ LG++ WFPW LWFS+G   S   +   VV+L LL  NTV ++ +E +++TPV+PG+N+P S   + +L ++   VLHE GHALAA +EKVR+ GFG   F I+PGAY +I+ +DL +L P R+L+I+ AG WHN V++ +   +   LP LL+P Y T  G+ V  + ++SV TG  GL+ GD IT++N CP+N+  +W+ C++ +Q  S    SGYC+P S +  LD S                                   +  K   V  + DCC+    S HLCF +  +    G+    PKY CLPAR VTER PC   S+C P +   D    C+ P+  +N + L+R+VH  +R+  +LFLG V +L+ ++ ISNY+PRW  L P  LP  + TF +YL ++SGAL+L N VPCY LDGQWI +A ++L L   +  R  +R L S +  LGT L+  N++++++++I + S
Sbjct:    7 LSYFFGFWALAYLIDAGLSVHPFTKQRYLELRGRSGISIQVLQARFFTQKLNPFFQRLGSVDWFPWGLWFSIGTAFSAIFMCLSVVVLSLLAYNTVMRKPIEKQIITPVMPGVNLPLSHIGFYMLTLLICVVLHEAGHALAALREKVRLHGFGFFLFGIYPGAYVDISDSDLCSLSPLRQLKIYCAGVWHNGVIVFLSLVVFHALPWLLVPAYSTNRGVGVVSVLEHSVFTGHRGLHSGDAITQINACPVNTAEEWYRCLEEVQQKS----SGYCVPGSYLNMLDPSHVRAQPGARRLSAVLPVDNQAEVAARLPRVSADTVAAPKALVVAASHDCCAPHLASTHLCFAHFHSLGKHGKQSRKPKYVCLPARAVTEREPCIAPSDCGPLATEGDQRPVCLIPAPPDNHTHLIRIVHNRARSPAILFLGPVEDLVASIEISNYVPRWPQLFPCRLPQLIATFCIYLFSLSGALVLLNVVPCYALDGQWILKALLDLLLPSFICGRQFKRILFSSIIALGTGLLSVNIALALWYLILETS 540
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BLAST of Membrane-bound transcription factor site-2 protease vs. TrEMBL
Match: K1PKA9 (Membrane-bound transcription factor site-2 protease OS=Crassostrea gigas OX=29159 GN=CGI_10008816 PE=4 SV=1)

HSP 1 Score: 369.392 bits (947), Expect = 1.636e-117
Identity = 196/492 (39.84%), Postives = 307/492 (62.40%), Query Frame = 3 
Query:  138 AFLIMIWSIIYVLDLTLKAHHKTQERYLIWYLNTGISFELLRIKWFTKRFNKYFQILGNLTWFP--WKLWFSLGVVVSFFAIIFGXXXXXXXXXNTVSQRVVEHEVLTPVVPGINVPFSDAVYLLLAIIFAAVLHELGHALAATKEKVRVDXXXXXXXXXXPGAYTNINSNDLDNLEPKRKLRIFAAGNWHNTVLLTVGFCIMKLLPILLLPFYRTGDGIAVSYLSQNSVLTGKLGLYQGDVITKVNNCPINSQTDWFNCMQRIQHDSESLNSGYCMPLSRIRQLDISSGFKTRTVWGNIDCCSNQTRSHLCFRYSSNYRFSGQIFHGPKYACLPARTVTERNPCQTNSNCYPQSHRPDLTCVTPSLENSSRLVRLVHSRTSPVLFLGNVNELLQTVIISNYIPRWILIPNNLPLHLETFLMYLITISGALILFNSVPCYMLDGQWIFQAAVELFLSGILPNRNARRKLCSCVTLLGTILIFTNVSMSIFFM 1607
            A ++  WS +Y+LD  LK+H      Y  +   TG S  + + +W++  FN+ F  +G   W P   +LWF++GV+    A++  V LL LLV+NT+ +  VE +VLTPV+PG+N+P S   Y LL ++   +LHE+GHA+AA +E VRV+GFGL    ++PGAY +++S  L  + P R+LRI+ AG WHN V++     ++ +LPILL+PFY TG  + ++ +S+NS ++G  GL  GD +T ++ C +    DW  C   + H  +  + G+C+   +I +LD +    T  V   +DCC++ + +HLCFRY    +         KYACLPAR  T+R  C+  S+CY    + D+ CV P+L+N ++L+++ H R  P+LFLG+  +L  +V++SNY+P+  +IP NLP  LETF  YLI++SGAL++ N VPCY LDGQWI  + +EL L+ ++P+R  R  + S + L GT L+  NV ++++ +
Sbjct:    8 ALILGFWSSLYLLDAYLKSHKTYSRHYFKFLERTGFSISICQCRWYSTLFNRSFVRIGQ--WRPRLLRLWFTVGVLFGLVAMLLSVCLLTLLVINTLRKEPVEQQVLTPVMPGVNLPTSHLSYYLLTLLVCGILHEMGHAIAAVRENVRVNGFGLFLLILYPGAYVDLSSEHLQVVSPLRQLRIYCAGVWHNFVIVIFALIVIFILPILLIPFYSTGSAVVITQVSENSAVSGPRGLAVGDPVTSISGCRVTDIEDWHAC---VTHSIKEESIGHCLSREKISELDATPKNLT-DVAKAVDCCNSTSSTHLCFRYHIKSKSQD------KYACLPARMTTDRPMCKYQSDCYIP--KADMVCVYPALDNVTKLLQVFHGRKPPLLFLGHPLDLHYSVVLSNYVPKSSIIPLNLPYVLETFSKYLISLSGALVILNVVPCYALDGQWICHSFIELSLTSVIPDREIRGLIYSVIILYGTALLLVNVILAMWML 485
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BLAST of Membrane-bound transcription factor site-2 protease vs. TrEMBL
Match: A0A1S3JB99 (membrane-bound transcription factor site-2 protease isoform X2 OS=Lingula unguis OX=7574 GN=LOC106171385 PE=4 SV=1)

HSP 1 Score: 365.925 bits (938), Expect = 5.029e-116
Identity = 193/492 (39.23%), Postives = 309/492 (62.80%), Query Frame = 3 
Query:  132 GFAFLIMIWSIIYVLDLTLKAHHKTQERYLIWYLNTGISFELLRIKWFTKRFNKYFQILGNLTWFPWKL--WFSLGVVVSFFAIIFGXXXXXXXXXNTVSQRVVEHEVLTPVVPGINVPFSDAVYLLLAIIFAAVLHELGHALAATKEKVRVDXXXXXXXXXXPGAYTNINSNDLDNLEPKRKLRIFAAGNWHNTVLLTVGFCIMKLLPILLLPFYRTGDGIAVSYLSQNSVLTGKLGLYQGDVITKVNNCPINSQTDWFNCMQRIQHDSESLNSGYCMPLSRIRQLDISSGFKTRTVWGNIDCCSNQTRSHLCFRYSSNYRFSGQIFHGPKYACLPARTVTERNPCQTNSNCYPQSHRPDLTCVTPSLENSSRLVRLVHSRTSPVLFLGNVNELLQTVIISNYIPRWILIPNNLPLHLETFLMYLITISGALILFNSVPCYMLDGQWIFQAAVELFLSGILPNRNARRKLCSCVTLLGTILIFTNVSMSIF 1601
            G A ++  WS +Y+LD  LK++  T   Y+ +   TGIS  + +I+W+TK  N+ F  +G   W P  L  WF+ GVV    A++  V LL L+V NT++++ +E +VLTPV+PG+N+P +   Y LL ++   +LHE+GHA+AA +E+VRV+GFG+    ++PGA+ ++ +  L  + P R+LRI+ AG WHN +++ V   +  LLP +L+ FY +G G+A++Y+ Q S ++G  GL  GD +T +N+C + +  DW  C+ +   D    +SGYCMP+  I   D+S      TV GNI+CC++ + +HLCF Y +    +       K+ACLPAR+ ++R PC+  S+C  ++ + +  CV PSL+NS+  +++     +P+LFLG+  +L  +V ISNY+P  + IP N+P  +ETF  YLI++SGAL + N VPCY LDGQWI  A +E  L   +P+ + R  + S + L GT+L+  N+ ++++
Sbjct:    5 GIAVILGTWSSVYLLDAFLKSNKSTARPYIEFLERTGISLSVGQIRWYTKCLNRVFLRMGQ--WKPRYLRTWFTAGVVFGMVAMLLSVCLLTLMVYNTLTRQHIEQQVLTPVMPGVNLPMNQIFYYLLTLLVCGILHEVGHAVAAVREQVRVNGFGIFILAVYPGAFVDLYTEHLQVISPIRQLRIYCAGVWHNFIIVIVALLVWFLLPWMLMLFYSSGTGVAITYVLQGSAVSGPRGLVTGDHVTSINHCRVTNVEDWMQCIGQSMKDP---SSGYCMPVGEIGVQDVSYNQNYVTVMGNIECCNSTSSTHLCFLYHTKASPNKL-----KHACLPARSTSDRPPCRLQSDC--RNPKVETACVYPSLDNSTTFLKVYRYGKAPLLFLGHPLDLHYSVHISNYVPVGVFIPLNMPYVIETFCQYLISLSGALAILNVVPCYALDGQWILLAFIEYTLRSTIPDSDIRGLIYSVIILFGTLLLTANIVIAMW 484
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BLAST of Membrane-bound transcription factor site-2 protease vs. TrEMBL
Match: A0A1S3JA13 (membrane-bound transcription factor site-2 protease isoform X1 OS=Lingula unguis OX=7574 GN=LOC106171385 PE=4 SV=1)

HSP 1 Score: 365.925 bits (938), Expect = 5.188e-116
Identity = 193/492 (39.23%), Postives = 309/492 (62.80%), Query Frame = 3 
Query:  132 GFAFLIMIWSIIYVLDLTLKAHHKTQERYLIWYLNTGISFELLRIKWFTKRFNKYFQILGNLTWFPWKL--WFSLGVVVSFFAIIFGXXXXXXXXXNTVSQRVVEHEVLTPVVPGINVPFSDAVYLLLAIIFAAVLHELGHALAATKEKVRVDXXXXXXXXXXPGAYTNINSNDLDNLEPKRKLRIFAAGNWHNTVLLTVGFCIMKLLPILLLPFYRTGDGIAVSYLSQNSVLTGKLGLYQGDVITKVNNCPINSQTDWFNCMQRIQHDSESLNSGYCMPLSRIRQLDISSGFKTRTVWGNIDCCSNQTRSHLCFRYSSNYRFSGQIFHGPKYACLPARTVTERNPCQTNSNCYPQSHRPDLTCVTPSLENSSRLVRLVHSRTSPVLFLGNVNELLQTVIISNYIPRWILIPNNLPLHLETFLMYLITISGALILFNSVPCYMLDGQWIFQAAVELFLSGILPNRNARRKLCSCVTLLGTILIFTNVSMSIF 1601
            G A ++  WS +Y+LD  LK++  T   Y+ +   TGIS  + +I+W+TK  N+ F  +G   W P  L  WF+ GVV    A++  V LL L+V NT++++ +E +VLTPV+PG+N+P +   Y LL ++   +LHE+GHA+AA +E+VRV+GFG+    ++PGA+ ++ +  L  + P R+LRI+ AG WHN +++ V   +  LLP +L+ FY +G G+A++Y+ Q S ++G  GL  GD +T +N+C + +  DW  C+ +   D    +SGYCMP+  I   D+S      TV GNI+CC++ + +HLCF Y +    +       K+ACLPAR+ ++R PC+  S+C  ++ + +  CV PSL+NS+  +++     +P+LFLG+  +L  +V ISNY+P  + IP N+P  +ETF  YLI++SGAL + N VPCY LDGQWI  A +E  L   +P+ + R  + S + L GT+L+  N+ ++++
Sbjct:    5 GIAVILGTWSSVYLLDAFLKSNKSTARPYIEFLERTGISLSVGQIRWYTKCLNRVFLRMGQ--WKPRYLRTWFTAGVVFGMVAMLLSVCLLTLMVYNTLTRQHIEQQVLTPVMPGVNLPMNQIFYYLLTLLVCGILHEVGHAVAAVREQVRVNGFGIFILAVYPGAFVDLYTEHLQVISPIRQLRIYCAGVWHNFIIVIVALLVWFLLPWMLMLFYSSGTGVAITYVLQGSAVSGPRGLVTGDHVTSINHCRVTNVEDWMQCIGQSMKDP---SSGYCMPVGEIGVQDVSYNQNYVTVMGNIECCNSTSSTHLCFLYHTKASPNKL-----KHACLPARSTSDRPPCRLQSDC--RNPKVETACVYPSLDNSTTFLKVYRYGKAPLLFLGHPLDLHYSVHISNYVPVGVFIPLNMPYVIETFCQYLISLSGALAILNVVPCYALDGQWILLAFIEYTLRSTIPDSDIRGLIYSVIILFGTLLLTANIVIAMW 484
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BLAST of Membrane-bound transcription factor site-2 protease vs. TrEMBL
Match: R7V2L5 (Uncharacterized protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_129824 PE=4 SV=1)

HSP 1 Score: 364.77 bits (935), Expect = 1.202e-115
Identity = 203/492 (41.26%), Postives = 301/492 (61.18%), Query Frame = 3 
Query:  138 AFLIMIWSIIYVLDLTLKAHHKTQERYLIWYLNTGISFELLRIKWFTKRFNKYFQILGNLTWFPWKLWFSLGVVVSFFAIIFGXXXXXXXXXNTVSQRVVEHEVLTPVVPGINVPFSDAVYLLLAIIFAAVLHELGHALAATKEKVRVDXXXXXXXXXXPGAYTNINSNDLDNLEPKRKLRIFAAGNWHNTVLLTVGFCIMKLLPILLLPFYRTGDGIAVSYLSQNSVLTGKLGLYQGDVITKVNNCPINSQTDWFNCMQRIQHDSESLNSGYCMPLSRIRQLDISSGFKTRTVWGNIDCCSNQTRSHLCFRYSSNYRFSGQIFHGPKYACLPARTVTERNPCQTNSNCYPQSHRPDLTCVTPSLENSSRLVRLVHSRTSPVLFLGNVNELLQTVIISNYIPRWILIPNNLPLHLETFLMYLITISGALILFNSVPCYMLDGQWIFQAAVELFLSGILPNRNARRKLCSCVTLLGTILIFTN--VSMSIFFM 1607
            A  +  W+ +Y+LD  LK H      Y+ +   TG+S  + +++W+T  FN+ F  +G+      K+WF+ GV     A++  V LL L+V NT+ Q+ +E ++LTPV+PG+N+P +   Y LL +    VLHE GHA+AA +E+VRV+GFG+  F ++PGA+ ++ +  L  + P R+LRI+ AG WHN V++ V    +  LP  LLPFY  G G+ V+ + +NS ++G  GL  GD IT V  C +N   DW  C   I     + + GYCM L  I+Q D+S    T T  GN++CC N + +HLCF Y S  + S  + H    ACLPART+T+R PC   S+C  +    D  CV PSL+NS++L+R++H    P+LFLG+  +L  ++ +SNY P+ ++IP +LP  LETF  YLI++SGAL + N VPCY LDGQWI  + +EL L   +PN   R  + +C+ L+GTIL+  N  ++M + FM
Sbjct:    8 ALFMGFWASLYLLDAFLKTHQGFSRSYINFLSRTGLSVSIAQLRWYTPYFNRLFVRIGSWKTHFLKVWFTCGVCFGLVAMLVSVFLLSLMVYNTLCQKPIEQQILTPVMPGVNLPSNQIGYYLLTLFTCGVLHEAGHAVAAVREQVRVNGFGVFIFILYPGAFVDLYTEHLQVISPLRQLRIYCAGVWHNFVIVVVAIFYLLCLPWFLLPFYSVGSGVIVTSVLENSAVSGPRGLSNGDCITNVGQCRVNHVNDWIRC---ISSSMVAPSDGYCMALDLIQQQDVSLPSYT-TPAGNVECCGNTSNTHLCFFYHS--KLSASLNH----ACLPARTITDRPPCHLQSDC--RIPGGDAVCVMPSLDNSTKLLRILHHDKPPLLFLGHPLDLHYSLTLSNYWPKALIIPLDLPYVLETFCKYLISLSGALAILNVVPCYALDGQWILLSFLELSLRSTVPNPETRGLIYTCLLLMGTILLSLNIFIAMWMLFM 487
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BLAST of Membrane-bound transcription factor site-2 protease vs. Ensembl Cavefish
Match: mbtps2 (membrane bound transcription factor peptidase, site 2 [Source:NCBI gene;Acc:103023831])

HSP 1 Score: 299.671 bits (766), Expect = 6.052e-94
Identity = 177/494 (35.83%), Postives = 289/494 (58.50%), Query Frame = 3 
Query:  156 WSIIYVLDLTLKAHHKTQERYLIWYLNTGISFELLRIKWFTKRFNKYFQILGNLTWFPWKLWFSLGVVVSFFAIIFGXXXXXXXXXNTVSQRVVE-----HE-VLTPVVPGINVPFSDAVYLLLAIIFAAVLHELGHALAATKEKVRVDXXXXXXXXXXPGAYTNINSNDLDNLEPKRKLRIFAAGNWHNTVLLTVGFCIMKLLPILLLPFYRTGDGIAVSYLSQNSVLTGKLGLYQGDVITKVNNCPINSQTDWFNCMQRIQHDSESLNSGYCMPLSRIRQLDISSGFKTRTVWGNIDCCSNQTRSHLCFRYSSNYRFSGQIFHGPKYACLPAR-TVTERNPCQTNSNCYPQSHRPDLTCVTPSLENSSRLVRLVHSRTSPVLFLGNVNELLQTVIISNYIPRWILIPNNLPLHLETFLMYLITISGALILFNSVPCYMLDGQWIFQAAVELFLSGILPNRNARRKLCSCVTLLGTILIFTNVSMSIFFMIKQ 1616
            W  +Y+LD  L++    +  Y  W  + G+S     I+W T  FN+ F    +       +WFS G+V    A+   VVLL   ++ T++  + E     HE VL  VVPG+N+P S   Y  +AI+ + ++HE GH +AA +E+VR++GFG+  F I+PGA+ ++ +  L+ + P ++LRIF AG WHN +L     C + LLP LL PFY TG G  ++ + + S  +G  GL+ GD++T++ +C +    DW +C+Q++ H  +   SGYC+P + + QL  ++G   + + G ++CCSN + + LCF YS+N            +ACLPAR T+     C+TN++C      P L CV PSLEN +RL+R+ H   + +LF+G  + L  +V ++N++PR   +  +LP+ LET   YL+++SGAL + N+VPC+ LDGQW+  A +E  L  ++P ++ R  L   + L G+ L+  NV++ ++ +  +
Sbjct:   14 WCTVYLLDTALRSSTSMKSSYESWLTSNGLSLSPFHIRWHTSLFNRLFARCSHFNPCFLYVWFSAGMVFGIVAMFGSVVLLGRTLMQTLAHMMAETPEGTHEQVLQVVVPGVNLPVSQLAYFFIAILVSGLIHEFGHGVAALREQVRLNGFGMFMFVIYPGAFVDLFTTHLNLISPVQQLRIFCAGVWHNFMLCVAAVCFLLLLPFLLFPFYYTGAGALITEVVEGSPSSGPRGLFVGDLVTRMEDCSVKGVEDWHSCIQQLSHQPQ---SGYCVPTATL-QLSRAAGRAYKRLDGTMECCSNSSMTDLCFAYSNN-------LESRLFACLPARKTIEASRTCRTNADCQ-VDFSPSL-CVIPSLENQTRLIRVKHPPQADMLFVGYPSHLQFSVSLTNFVPRLGFLHLDLPVMLETLSKYLVSLSGALAVVNAVPCFALDGQWMLTAFLEATLCSLIPEKSNRELLGFFILLGGSTLLAANVALGLWMVTAR 494
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BLAST of Membrane-bound transcription factor site-2 protease vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004179.1 (pep scaffold:Pmarinus_7.0:GL490440:2728:6306:-1 gene:ENSPMAG00000003812.1 transcript:ENSPMAT00000004179.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 139.428 bits (350), Expect = 1.908e-37
Identity = 95/283 (33.57%), Postives = 147/283 (51.94%), Query Frame = 3 
Query:  807 SQNSVLTGKLGLYQGDVITKVNNCPINSQTDWFNCMQRIQHDSESLNSGYCMPLSRIRQLDISSGFKT-RTVWGNIDCCSNQTRSHLCFRYSSNYRFSGQIFHGPKYACLPARTV-TERNPCQTNSNCYPQSHRPDLT-------------CVTPSLENSSRLVRLVHSRTSPVLFLGNVNELLQTVIISNYIPRWILIPNNLPLHLETFLMYLITISGALILFNSVPCYMLDGQWIFQAAVELFLSGILPNRNARRKLCSCVTLLGTILIFTNVSMSIFFMI 1610
            +Q+S + G LGL  GDV+T V  C +     W  C+     ++     G+C+  + +  L +       R   G+++CC N + + LCF YS  Y  S       KYACL  R V  E   C +N++C   +                   CV P+L N +RL+R+VH+     L++G+  + L +V +S+Y+PR+  +  +LP  LETF  YL+++SGAL L NSVPC+ LDGQWI  A +EL L+G         ++ S V L GT L+  NV + ++ ++
Sbjct:    1 AQDSGVGGGLGLRVGDVVTTVGECSVAGAARWAGCLV---EEAARPPQGFCLSSAGLHLLLLQRPASVYRREDGSVECCRNGSETDLCFSYS--YSSSNA-----KYACLSVRRVLGESRACGSNADCRGAAAAAAAAGGEGGGGGDAGALCVCPALGNGTRLLRVVHAPRPHTLYVGHPLQPLYSVTMSDYVPRFTFLSIHLPPMLETFCKYLVSLSGALALVNSVPCFALDGQWILTALLELVLTG-------HERVASLVLLGGTALLAGNVCLGMWTLV 266
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BLAST of Membrane-bound transcription factor site-2 protease vs. Ensembl Nematostella
Match: EDO41093 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S5C2])

HSP 1 Score: 306.99 bits (785), Expect = 2.920e-97
Identity = 184/489 (37.63%), Postives = 291/489 (59.51%), Query Frame = 3 
Query:  141 FLIMIWSIIYVLDLTLKAHHKTQERYLIWYLNTGISFELLRIKWFTKRFNKYFQILGNLTWFPWKLWFSLGVVVSFFAIIFGXXXXXXXXXNTVSQRVVEHEVLTPVVPGINVPFSDAVYLLLAIIFAAVLHELGHALAATKEKVRVDXXXXXXXXXXPGAYTNINSNDLDNLEPKRKLRIFAAGNWHNTVLLTVGFCIMKLLPILLLPFYRTGDGIAVSYLSQNSVLTGKLGLYQGDVITKVNNCPINSQTDWFNCMQRIQHDSESLNSGYCMPLSRIRQLDISSGFKTRTVWGNIDCCSN-QTRSHLCFRYSSNYRFSGQIFHGPKYACLPARTVTERNP-CQTNSNCYPQSHRPDLTCVTPSLENSSRLVRLVHSRTSPVLFLGNVNELLQTVIISNYIPRWILIPNNLPLHLETFLMYLITISGALILFNSVPCYMLDGQWIFQAAVELFLSGILPNRNARRKLCSCVTLLGTILIFTNVSMSIF 1601
             +I  W+++++++  LK + K   RY  +  + GI+  L +I+W+T + N++F   G L  +   LWFSLGV V    +   V++L L +    ++   E +VLTPV+PG+N+P+S  +Y L+ +  + V HE+GHA+AA +E+VRV+GFG+ F  I+PGAY ++ ++ L  + P R+LRI+ AG WHN +L+ +G  ++  LP LL+P Y    G  V+ +S+NS + G +   +GD I  V  CP+N++ DW  C+ R  +  +    GYC  +  + + + S G  T  V+   +CC N  T S LCFRY S     G       YACL AR++ + +  C    +C+   ++    CV PSL+NSSRL+R+       VL++G+   L  TV + NY PR  ++P  LP  +ETFL+YLI++SGAL L N VPCY LDGQW   A V+  L  I+PN + R  LC+ +  +GT+L+  N++++++
Sbjct:    9 LVIFFWTLVFIVNAVLKNYRKYSRRYKEFLEDHGITMSLCQIRWYTTQLNRWFIWFGRLHPYLLHLWFSLGVFVGVGLMALSVMVLSLTLYQAFTKEAPE-QVLTPVMPGVNLPWSQLMYYLITLAVSGVFHEMGHAVAAVREQVRVNGFGMFFMAIYPGAYVDLYTDHLTMISPIRQLRIYCAGVWHNVILVLLGLLLLWSLPYLLVPLYMADQGAVVTKVSRNSPVFGSIN--RGDTIYSVYGCPVNNKNDWIQCVSRTLNSPQH---GYCSNMFTVTRQNSSQGSFTDGVY---ECCGNLTTSSRLCFRYESIKSEKG-------YACLAARSIMQASQFCSLPEHCHGPGNK---ACVHPSLDNSSRLIRVRRLGGPDVLYVGDPILLQYTVAVVNYSPRSPILPMELPTIIETFLIYLISLSGALALLNIVPCYSLDGQWALFALVDHTLGNIIPNEDQRSTLCTVILTMGTLLLAANITLALW 478
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BLAST of Membrane-bound transcription factor site-2 protease vs. Ensembl Medaka
Match: mbtps2 (membrane bound transcription factor peptidase, site 2 [Source:NCBI gene;Acc:101156537])

HSP 1 Score: 287.73 bits (735), Expect = 2.942e-89
Identity = 164/470 (34.89%), Postives = 257/470 (54.68%), Query Frame = 3 
Query:  156 WSIIYVLDLTLKAHHKTQERYLIWYLNTGISFELLRIKWFTKRFNKYFQILGNLTWFPWKLWFSLGVVVSFFAIIFGXXXXXXXXXNTVSQ------RVVEHEVLTPVVPGINVPFSDAVYLLLAIIFAAVLHELGHALAATKEKVRVDXXXXXXXXXXPGAYTNINSNDLDNLEPKRKLRIFAAGNWHNTVLLTVGFCIMKLLPILLLPFYRTGDGIAVSYLSQNSVLTGKLGLYQGDVITKVNNCPINSQTDWFNCMQRIQHDSESLNSGYCMPLSRIRQLDISSGFKTRTVWGNIDCCSNQTRSHLCFRYSSNYRFSGQIFHGPKYACLPART-VTERNPCQTNSNC----YPQSHRPDLTCVTPSLENSSRLVRLVHSRTSPVLFLGNVNELLQTVIISNYIPRWILIPNNLPLHLETFLMYLITISGALILFNSVPCYMLDGQWIFQAAVELFLSGILPNRNARR 1532
            W  +Y+ D  L++    +  Y  W  + G+      ++W T  FN+ F     +      LWFS G++    A++  VVLL   +  T +Q      R+   + L  VVPG+N+P S  VY   A++ + V+HELGHA+AA +E+VRV+GFG+  F ++PGA+ ++ +  L+ + P ++LRIF AG WHN VL       + L+P+ L P Y TG G  V+ + Q S   G  GL  GD++T + +CP+    DW  C+ R+   S     GYC+P++ + Q   + G   + + G  DCCSN + + LCF YS       +     +YAC+P R  VT    C+++ +C              CVTPSLEN +R +R+ H   + +LF+G    L   V ++N+IPR+  +  ++P+ LETF  Y++++SGAL + NSVPC+ LDGQW+  A +E  L  ++ +R  R 
Sbjct:   14 WCAVYLTDTLLRSSTTHRVSYESWLSSRGLVVSPFHVRWQTTVFNRLFAYCARIHPPALHLWFSSGLMFGVGAMLGSVVLLIRTLQQTYAQMTSDNPRIGAQQALQVVVPGVNLPTSQLVYFFTALLLSGVVHELGHAVAALREQVRVNGFGIFLFVLYPGAFVDLFTTHLNLISPAQQLRIFCAGVWHNFVLCLAALAFIFLMPVFLFPLYSTGGGALVTEVVQGSAADGPRGLSVGDIVTALEDCPVRGVEDWTGCLSRL---SRLPQMGYCVPVASL-QPSWAHGRAFKRLDGTTDCCSNSSLTDLCFSYS-------RAASSREYACIPVRKMVTGTRVCRSDRDCAARSSAARSSAASVCVTPSLENQTRFIRVTHPPNTHMLFVGYPPHLQHAVTLTNFIPRFSFLHLHVPVFLETFCKYVVSLSGALAVVNSVPCFALDGQWMLNALLEATLVTVVTDRQKRE 472
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BLAST of Membrane-bound transcription factor site-2 protease vs. Ensembl Medaka
Match: mbtps2 (membrane bound transcription factor peptidase, site 2 [Source:NCBI gene;Acc:101156537])

HSP 1 Score: 264.233 bits (674), Expect = 1.094e-75
Identity = 140/373 (37.53%), Postives = 215/373 (57.64%), Query Frame = 3 
Query:  429 RVVEHEVLTPVVPGINVPFSDAVYLLLAIIFAAVLHELGHALAATKEKVRVDXXXXXXXXXXPGAYTNINSNDLDNLEPKRKLRIFAAGNWHNTVLLTVGFCIMKLLPILLLPFYRTGDGIAVSYLSQNSVLTGKLGLYQGDVITKVNNCPINSQTDWFNCMQRIQHDSESLNSGYCMPLSRIRQLDISSGFKTRTVWGNIDCCSNQTRSHLCFRYSSNYRFSGQIFHGPKYACLPAR-TVTERNPCQTNSNC----YPQSHRPDLTCVTPSLENSSRLVRLVHSRTSPVLFLGNVNELLQTVIISNYIPRWILIPNNLPLHLETFLMYLITISGALILFNSVPCYMLDGQWIFQAAVELFLSGILPNRNARR 1532
            R+   + L  VVPG+N+P S  VY   A++ + V+HELGHA+AA +E+VRV+GFG+  F ++PGA+ ++ +  L+ + P ++LRIF AG WHN VL       + L+P+ L P Y TG G  V+ + Q S   G  GL  GD++T + +CP+    DW  C+ R+   S     GYC+P++ + Q   + G   + + G  DCCSN + + LCF YS             +YAC+P R  VT    C+++ +C              CVTPSLEN +R +R+ H   + +LF+G    L   V ++N+IPR+  +  ++P+ LETF  Y++++SGAL + NSVPC+ LDGQW+  A +E  L  ++ +R  R 
Sbjct:  766 RIGAQQALQVVVPGVNLPTSQLVYFFTALLLSGVVHELGHAVAALREQVRVNGFGIFLFVLYPGAFVDLFTTHLNLISPAQQLRIFCAGVWHNFVLCLAALAFIFLMPVFLFPLYSTGGGALVTEVVQGSAADGPRGLSVGDIVTALEDCPVRGVEDWTGCLSRL---SRLPQMGYCVPVASL-QPSWAHGRAFKRLDGTTDCCSNSSLTDLCFSYSRAAS-------SREYACIPVRKMVTGTRVCRSDRDCAARSSAARSSAASVCVTPSLENQTRFIRVTHPPNTHMLFVGYPPHLQHAVTLTNFIPRFSFLHLHVPVFLETFCKYVVSLSGALAVVNSVPCFALDGQWMLNALLEATLVTVVTDRQKRE 1127
The following BLAST results are available for this feature:
BLAST of Membrane-bound transcription factor site-2 protease vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 2
Match NameE-valueIdentityDescription
MBTPS21.406e-7632.04membrane bound transcription factor peptidase, sit... [more]
MBTPS27.491e-3732.28membrane bound transcription factor peptidase, sit... [more]
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BLAST of Membrane-bound transcription factor site-2 protease vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1
Match NameE-valueIdentityDescription
Y56A3A.27.003e-5332.73pep chromosome:WBcel235:III:11849951:11862249:-1 g... [more]
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BLAST of Membrane-bound transcription factor site-2 protease vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1
Match NameE-valueIdentityDescription
S2P2.286e-4827.60gene:FBgn0033656 transcript:FBtr0088063[more]
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BLAST of Membrane-bound transcription factor site-2 protease vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
mbtps25.941e-9135.43membrane-bound transcription factor peptidase, sit... [more]
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BLAST of Membrane-bound transcription factor site-2 protease vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 3
Match NameE-valueIdentityDescription
mbtps22.303e-9236.09membrane bound transcription factor peptidase, sit... [more]
mbtps21.955e-8935.66membrane bound transcription factor peptidase, sit... [more]
mbtps26.203e-8936.33membrane bound transcription factor peptidase, sit... [more]
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BLAST of Membrane-bound transcription factor site-2 protease vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 3
Match NameE-valueIdentityDescription
Mbtps25.475e-8032.04membrane-bound transcription factor peptidase, sit... [more]
Mbtps22.576e-2030.58membrane-bound transcription factor peptidase, sit... [more]
Mbtps27.220e-844.68membrane-bound transcription factor peptidase, sit... [more]
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BLAST of Membrane-bound transcription factor site-2 protease vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|O54862|MBTP2_CRIGR1.773e-7932.35Membrane-bound transcription factor site-2 proteas... [more]
sp|Q8CHX6|MBTP2_MOUSE3.830e-7932.04Membrane-bound transcription factor site-2 proteas... [more]
sp|Q0III2|MBTP2_BOVIN1.286e-7832.17Membrane-bound transcription factor site-2 proteas... [more]
sp|O43462|MBTP2_HUMAN6.753e-7632.04Membrane-bound transcription factor site-2 proteas... [more]
sp|Q5RAC8|MBTP2_PONAB5.921e-7531.72Membrane-bound transcription factor site-2 proteas... [more]
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BLAST of Membrane-bound transcription factor site-2 protease vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0X3PPF01.477e-11738.85Membrane-bound transcription factor site-2 proteas... [more]
K1PKA91.636e-11739.84Membrane-bound transcription factor site-2 proteas... [more]
A0A1S3JB995.029e-11639.23membrane-bound transcription factor site-2 proteas... [more]
A0A1S3JA135.188e-11639.23membrane-bound transcription factor site-2 proteas... [more]
R7V2L51.202e-11541.26Uncharacterized protein OS=Capitella teleta OX=283... [more]
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BLAST of Membrane-bound transcription factor site-2 protease vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
mbtps26.052e-9435.83membrane bound transcription factor peptidase, sit... [more]
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BLAST of Membrane-bound transcription factor site-2 protease vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
ENSPMAT00000004179.11.908e-3733.57pep scaffold:Pmarinus_7.0:GL490440:2728:6306:-1 ge... [more]
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BLAST of Membrane-bound transcription factor site-2 protease vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Membrane-bound transcription factor site-2 protease vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO410932.920e-9737.63Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Membrane-bound transcription factor site-2 protease vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 2
Match NameE-valueIdentityDescription
mbtps22.942e-8934.89membrane bound transcription factor peptidase, sit... [more]
mbtps21.094e-7537.53membrane bound transcription factor peptidase, sit... [more]
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BLAST of Membrane-bound transcription factor site-2 protease vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 0
Match NameE-valueIdentityDescription
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30020064 ID=SMED30020064|Name=Membrane-bound transcription factor site-2 protease|organism=Schmidtea mediterranea sexual|type=transcript|length=1987bp
CAAATATTTAAATTTATTCACATTATTTCAATATGACATAAAATATTTTA
ATTATTAAGATTTATTTGTTATTCTTTTATTAAAAATTATTTCAAAATAA
GTGTGCGATTTTATCTTTTACTATAATGATGGGTTTTGCATTTTTAATAA
TGATTTGGAGTATTATTTATGTTTTGGATTTGACATTGAAAGCCCATCAT
AAAACCCAAGAACGTTACTTAATTTGGTATCTTAATACTGGAATCTCATT
TGAATTACTCAGAATTAAATGGTTTACGAAGCGATTCAACAAATATTTTC
AAATTTTGGGTAATTTGACCTGGTTTCCTTGGAAATTGTGGTTTTCATTG
GGTGTCGTTGTTTCGTTTTTTGCCATTATATTCGGAGTTGTTCTTTTATG
CTTACTAGTTGTTAACACAGTTAGTCAGAGAGTTGTCGAGCATGAAGTTT
TAACTCCTGTGGTGCCGGGAATTAACGTCCCGTTTTCTGACGCTGTCTAT
CTGTTGTTAGCAATTATTTTCGCAGCAGTTTTGCACGAGTTAGGTCATGC
ATTAGCGGCAACAAAGGAAAAAGTTCGTGTTGATGGATTTGGATTGATAT
TTTTCTTTATCTTTCCTGGTGCATATACAAACATCAATTCAAATGATTTG
GACAATCTTGAACCTAAAAGAAAACTCAGAATATTTGCTGCTGGTAATTG
GCATAATACTGTGTTGTTAACAGTTGGATTTTGTATTATGAAATTATTAC
CGATATTGCTATTGCCATTTTATAGAACTGGTGATGGCATTGCTGTCAGT
TATTTAAGTCAGAATTCAGTACTAACTGGGAAATTGGGCTTGTATCAAGG
AGACGTGATTACCAAAGTAAACAATTGTCCGATCAACAGTCAAACTGATT
GGTTTAATTGTATGCAACGCATTCAACACGATTCGGAATCTCTGAATTCC
GGTTATTGCATGCCACTTAGCCGAATTCGGCAATTGGATATATCCTCTGG
ATTCAAAACCAGAACGGTTTGGGGTAACATTGACTGCTGTTCAAATCAAA
CTCGATCTCATTTATGCTTTCGGTACTCCAGTAATTACCGTTTTTCTGGA
CAGATTTTTCACGGCCCCAAATATGCTTGCCTGCCTGCTAGAACTGTAAC
AGAGAGAAATCCTTGTCAAACGAACTCCAATTGTTACCCTCAAAGTCATC
GACCTGATTTGACTTGTGTTACCCCAAGTTTAGAAAATTCAAGTCGCCTC
GTCAGGCTTGTTCATTCAAGGACATCGCCTGTATTATTTTTGGGAAATGT
AAACGAGCTTTTGCAAACAGTGATAATCAGCAACTATATTCCTAGATGGA
TTTTGATACCAAATAATTTACCATTACATTTAGAAACTTTTCTGATGTAT
TTAATAACCATATCAGGAGCACTGATCCTATTCAATTCTGTGCCGTGCTA
CATGCTCGACGGCCAGTGGATATTTCAAGCAGCAGTTGAATTATTTTTAT
CGGGAATTTTACCGAATCGTAATGCTAGACGGAAATTATGTTCATGTGTT
ACTTTGCTCGGGACGATTCTTATTTTCACCAATGTCAGCATGAGTATATT
TTTCATGATCAAACAATATTCTTGAAGATTTGCCTCAGAATTTTTACATT
TGTAAAGTGTTTATATATTTTGAAATTGTTATTTTCTTAATTGGTCTATT
ACTACGATTATTATTACTATTGCTATTATTACTATCGTTTTTGCCTATTT
GGATCAACTCGTGCGCCTGGATAATTTTGCTAATCTGTAAATATATATAA
ATGTTCGATTTGATTCAATTTTCTATTTTGTGTAGCATTTATACAATGAC
AGCCGCTATTCTCTGTACATTTTACATTGGTTTTGATGCATTTATTCATT
ATATATAAAGTTGTTACATTGAATCTTATTTTTATGGTGACAGCTTTGAT
TTCAAAACATTTTTCAAAAATATTGATCATTCTTAAG
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protein sequence of SMED30020064-orf-1

>SMED30020064-orf-1 ID=SMED30020064-orf-1|Name=SMED30020064-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=500bp
MMGFAFLIMIWSIIYVLDLTLKAHHKTQERYLIWYLNTGISFELLRIKWF
TKRFNKYFQILGNLTWFPWKLWFSLGVVVSFFAIIFGVVLLCLLVVNTVS
QRVVEHEVLTPVVPGINVPFSDAVYLLLAIIFAAVLHELGHALAATKEKV
RVDGFGLIFFFIFPGAYTNINSNDLDNLEPKRKLRIFAAGNWHNTVLLTV
GFCIMKLLPILLLPFYRTGDGIAVSYLSQNSVLTGKLGLYQGDVITKVNN
CPINSQTDWFNCMQRIQHDSESLNSGYCMPLSRIRQLDISSGFKTRTVWG
NIDCCSNQTRSHLCFRYSSNYRFSGQIFHGPKYACLPARTVTERNPCQTN
SNCYPQSHRPDLTCVTPSLENSSRLVRLVHSRTSPVLFLGNVNELLQTVI
ISNYIPRWILIPNNLPLHLETFLMYLITISGALILFNSVPCYMLDGQWIF
QAAVELFLSGILPNRNARRKLCSCVTLLGTILIFTNVSMSIFFMIKQYS*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0000070intestinal phagocyte
PLANA:0000103central nervous system
Vocabulary: INTERPRO
TermDefinition
IPR036034PDZ_sf
IPR001193MBTPS2
IPR008915Peptidase_M50
IPR001478PDZ
Vocabulary: molecular function
TermDefinition
GO:0004222metalloendopeptidase activity
GO:0005515protein binding
GO:0008233peptidase activity
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
Vocabulary: biological process
TermDefinition
GO:0006508proteolysis
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001193Membrane-bound transcription factor site-2 proteasePRINTSPR01000SREBPS2PTASEcoord: 134..148
score: 45.83
coord: 150..165
score: 39.84
coord: 111..130
score: 29.38
IPR001193Membrane-bound transcription factor site-2 proteasePANTHERPTHR13325PROTEASE M50 MEMBRANE-BOUND TRANSCRIPTION FACTOR SITE 2 PROTEASEcoord: 4..492
IPR036034PDZ superfamilyGENE3DG3DSA:2.30.42.10coord: 215..274
e-value: 4.4E-5
score: 25.2
IPR036034PDZ superfamilySUPERFAMILYSSF50156PDZ domain-likecoord: 220..267
IPR008915Peptidase M50PFAMPF02163Peptidase_M50coord: 126..466
e-value: 3.3E-20
score: 72.4
NoneNo IPR availablePANTHERPTHR13325:SF3MEMBRANE-BOUND TRANSCRIPTION FACTOR SITE-2 PROTEASEcoord: 4..492
NoneNo IPR availableSIGNALP_EUKSignalP-noTMSignalP-noTMcoord: 1..18
score: 0.715
NoneNo IPR availableTMHMMTMhelixcoord: 415..437
NoneNo IPR availableTMHMMTMhelixcoord: 194..216
NoneNo IPR availableTMHMMTMhelixcoord: 152..170
NoneNo IPR availableTMHMMTMhelixcoord: 31..50
NoneNo IPR availableTMHMMTMhelixcoord: 123..145
NoneNo IPR availableTMHMMTMhelixcoord: 71..93
NoneNo IPR availableTMHMMTMhelixcoord: 2..21
NoneNo IPR availableTMHMMTMhelixcoord: 471..493
NoneNo IPR availableTMHMMTMhelixcoord: 447..464