Actinin alpha

Overview


Name	Actinin alpha
Smed ID	SMED30020038
Length (bp)	463

Neoblast Clusters

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Actinin alpha (SMED30020038) t-SNE clustered cells

Violin plots show distribution of expression levels for Actinin alpha (SMED30020038) in cells (dots) of each of the 12 neoblast clusters.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30020038

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 10

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
cephalic ganglia	SMED30020038	h1SMcG0003060	dd_Smed_v4_5647_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
muscle cell	SMED30020038	h1SMcG0003060	dd_Smed_v4_5647_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30020038	h1SMcG0003060	Contig33524	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30020038	h1SMcG0003060	Contig33524	newmark_ests	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30020038	h1SMcG0003060	dd_Smed_v4_10174_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
muscle cell	SMED30020038	h1SMcG0003060	dd_Smed_v4_10174_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30020038	h1SMcG0003060	Contig6221	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30020038	h1SMcG0003060	Contig6221	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30020038	h1SMcG0003060	Contig49671	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30020038	h1SMcG0003060	Contig49671	newmark_ests	PMID:29674431 Fincher et al., 2018

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of Actinin alpha vs. Ensembl Human
Match: ACTN2 (actinin alpha 2 [Source:HGNC Symbol;Acc:HGNC:164])

HSP 1 Score: 182.57 bits (462), Expect = 1.020e-59
Identity = 82/109 (75.23%), Postives = 95/109 (87.16%), Query Frame = 2

Query:  137 WDREAFLDPMWELQQKKTFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
            WDR+  LDP WE QQ+KTFTAWCNSHLRKA  QI NIE+DF +GL L+ LLE +SGE LPKPD+G MRFHKIANVNKAL+YI S+GV+L+++GAEEIVDGNVKMTLGMI
Sbjct:    7 WDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPKPDRGKMRFHKIANVNKALDYIASKGVKLVSIGAEEIVDGNVKMTLGMI 115

[Close]

BLAST of Actinin alpha vs. Ensembl Human
Match: ACTN2 (actinin alpha 2 [Source:HGNC Symbol;Acc:HGNC:164])

HSP 1 Score: 181.8 bits (460), Expect = 1.180e-58
Identity = 82/109 (75.23%), Postives = 95/109 (87.16%), Query Frame = 2

Query:  137 WDREAFLDPMWELQQKKTFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
            WDR+  LDP WE QQ+KTFTAWCNSHLRKA  QI NIE+DF +GL L+ LLE +SGE LPKPD+G MRFHKIANVNKAL+YI S+GV+L+++GAEEIVDGNVKMTLGMI
Sbjct:   26 WDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPKPDRGKMRFHKIANVNKALDYIASKGVKLVSIGAEEIVDGNVKMTLGMI 134

[Close]

BLAST of Actinin alpha vs. Ensembl Human
Match: ACTN2 (actinin alpha 2 [Source:HGNC Symbol;Acc:HGNC:164])

HSP 1 Score: 181.415 bits (459), Expect = 1.759e-57
Identity = 82/109 (75.23%), Postives = 95/109 (87.16%), Query Frame = 2

Query:  137 WDREAFLDPMWELQQKKTFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
            WDR+  LDP WE QQ+KTFTAWCNSHLRKA  QI NIE+DF +GL L+ LLE +SGE LPKPD+G MRFHKIANVNKAL+YI S+GV+L+++GAEEIVDGNVKMTLGMI
Sbjct:   26 WDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPKPDRGKMRFHKIANVNKALDYIASKGVKLVSIGAEEIVDGNVKMTLGMI 134

[Close]

BLAST of Actinin alpha vs. Ensembl Human
Match: ACTN2 (actinin alpha 2 [Source:HGNC Symbol;Acc:HGNC:164])

HSP 1 Score: 183.726 bits (465), Expect = 5.176e-54
Identity = 82/109 (75.23%), Postives = 95/109 (87.16%), Query Frame = 2

Query:  137 WDREAFLDPMWELQQKKTFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
            WDR+  LDP WE QQ+KTFTAWCNSHLRKA  QI NIE+DF +GL L+ LLE +SGE LPKPD+G MRFHKIANVNKAL+YI S+GV+L+++GAEEIVDGNVKMTLGMI
Sbjct:   21 WDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPKPDRGKMRFHKIANVNKALDYIASKGVKLVSIGAEEIVDGNVKMTLGMI 129

[Close]

BLAST of Actinin alpha vs. Ensembl Human
Match: ACTN2 (actinin alpha 2 [Source:HGNC Symbol;Acc:HGNC:164])

HSP 1 Score: 183.726 bits (465), Expect = 5.616e-54
Identity = 82/109 (75.23%), Postives = 95/109 (87.16%), Query Frame = 2

Query:  137 WDREAFLDPMWELQQKKTFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
            WDR+  LDP WE QQ+KTFTAWCNSHLRKA  QI NIE+DF +GL L+ LLE +SGE LPKPD+G MRFHKIANVNKAL+YI S+GV+L+++GAEEIVDGNVKMTLGMI
Sbjct:   26 WDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPKPDRGKMRFHKIANVNKALDYIASKGVKLVSIGAEEIVDGNVKMTLGMI 134

[Close]

BLAST of Actinin alpha vs. Ensembl Celegans
Match: atn-1 (AcTiniN [Source:UniProtKB/TrEMBL;Acc:Q9XVU8])

HSP 1 Score: 181.8 bits (460), Expect = 1.155e-53
Identity = 82/109 (75.23%), Postives = 93/109 (85.32%), Query Frame = 2

Query:  137 WDREAFLDPMWELQQKKTFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
            WDRE  LDP WE QQKKTFTAWCNSHLRKA   I  IE+DF +GL L+ LLE +SGE LPKPD+G MRFHKIANVNKAL YIES+GV+L+++GAEEIVDGNVKMTLG+I
Sbjct:   25 WDREGLLDPAWEKQQKKTFTAWCNSHLRKAGTSIDTIEEDFRNGLKLMLLLEVISGEPLPKPDRGKMRFHKIANVNKALEYIESKGVKLVSIGAEEIVDGNVKMTLGLI 133

[Close]

BLAST of Actinin alpha vs. Ensembl Celegans
Match: atn-1 (AcTiniN [Source:UniProtKB/TrEMBL;Acc:Q9XVU8])

HSP 1 Score: 181.8 bits (460), Expect = 1.224e-53
Identity = 82/109 (75.23%), Postives = 93/109 (85.32%), Query Frame = 2

Query:  137 WDREAFLDPMWELQQKKTFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
            WDRE  LDP WE QQKKTFTAWCNSHLRKA   I  IE+DF +GL L+ LLE +SGE LPKPD+G MRFHKIANVNKAL YIES+GV+L+++GAEEIVDGNVKMTLG+I
Sbjct:   25 WDREGLLDPAWEKQQKKTFTAWCNSHLRKAGTSIDTIEEDFRNGLKLMLLLEVISGEPLPKPDRGKMRFHKIANVNKALEYIESKGVKLVSIGAEEIVDGNVKMTLGLI 133

[Close]

BLAST of Actinin alpha vs. Ensembl Celegans
Match: atn-1 (AcTiniN [Source:UniProtKB/TrEMBL;Acc:Q9XVU8])

HSP 1 Score: 107.457 bits (267), Expect = 1.547e-27
Identity = 48/62 (77.42%), Postives = 57/62 (91.94%), Query Frame = 2

Query:  278 IYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
            + LLE +SGE LPKPD+G MRFHKIANVNKAL YIES+GV+L+++GAEEIVDGNVKMTLG+I
Sbjct:    1 MLLLEVISGEPLPKPDRGKMRFHKIANVNKALEYIESKGVKLVSIGAEEIVDGNVKMTLGLI 62

[Close]

BLAST of Actinin alpha vs. Ensembl Celegans
Match: atn-1 (AcTiniN [Source:UniProtKB/TrEMBL;Acc:Q9XVU8])

HSP 1 Score: 106.686 bits (265), Expect = 2.599e-27
Identity = 48/62 (77.42%), Postives = 57/62 (91.94%), Query Frame = 2

Query:  278 IYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
            + LLE +SGE LPKPD+G MRFHKIANVNKAL YIES+GV+L+++GAEEIVDGNVKMTLG+I
Sbjct:    1 MLLLEVISGEPLPKPDRGKMRFHKIANVNKALEYIESKGVKLVSIGAEEIVDGNVKMTLGLI 62

[Close]

BLAST of Actinin alpha vs. Ensembl Celegans
Match: sma-1 (SMAll [Source:UniProtKB/TrEMBL;Acc:G5EFW3])

HSP 1 Score: 102.834 bits (255), Expect = 6.154e-26
Identity = 44/95 (46.32%), Postives = 71/95 (74.74%), Query Frame = 2

Query:  179 QKKTFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
            QKKTFT WCNS L +A+++I ++ +D   G+ L+ LLE +SG+ L KP++G MR  K+ N+NK L++++ + +QL N+GAE+I+D N ++ LG+I
Sbjct:  156 QKKTFTKWCNSFLNRASLEIVDLFEDVGDGIMLMKLLEIISGDKLGKPNRGRMRVQKVENLNKVLDFLKKKKIQLENIGAEDILDRNERLILGLI 250

[Close]

BLAST of Actinin alpha vs. Ensembl Fly
Match: Actn (gene:FBgn0000667 transcript:FBtr0310657)

HSP 1 Score: 171.4 bits (433), Expect = 7.394e-50
Identity = 77/105 (73.33%), Postives = 90/105 (85.71%), Query Frame = 2

Query:  149 AFLDPMWELQQKKTFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
              LDP WE QQKKTFTAWCNSHLRKA   I NIE+DF +GL L+ LLE +SGE+LPKPD+G MRFHKIANVNKAL++I S+GV L+++GAEEIVDGN+KMTLGMI
Sbjct:   26 GLLDPAWEKQQKKTFTAWCNSHLRKAGTAIDNIEEDFRNGLKLMLLLEVISGETLPKPDRGKMRFHKIANVNKALDFIASKGVHLVSIGAEEIVDGNLKMTLGMI 130

[Close]

BLAST of Actinin alpha vs. Ensembl Fly
Match: Actn (gene:FBgn0000667 transcript:FBtr0070344)

HSP 1 Score: 171.4 bits (433), Expect = 7.653e-50
Identity = 77/105 (73.33%), Postives = 90/105 (85.71%), Query Frame = 2

Query:  149 AFLDPMWELQQKKTFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
              LDP WE QQKKTFTAWCNSHLRKA   I NIE+DF +GL L+ LLE +SGE+LPKPD+G MRFHKIANVNKAL++I S+GV L+++GAEEIVDGN+KMTLGMI
Sbjct:   26 GLLDPAWEKQQKKTFTAWCNSHLRKAGTAIDNIEEDFRNGLKLMLLLEVISGETLPKPDRGKMRFHKIANVNKALDFIASKGVHLVSIGAEEIVDGNLKMTLGMI 130

[Close]

BLAST of Actinin alpha vs. Ensembl Fly
Match: Actn (gene:FBgn0000667 transcript:FBtr0333801)

HSP 1 Score: 171.4 bits (433), Expect = 7.729e-50
Identity = 77/105 (73.33%), Postives = 90/105 (85.71%), Query Frame = 2

Query:  149 AFLDPMWELQQKKTFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
              LDP WE QQKKTFTAWCNSHLRKA   I NIE+DF +GL L+ LLE +SGE+LPKPD+G MRFHKIANVNKAL++I S+GV L+++GAEEIVDGN+KMTLGMI
Sbjct:   26 GLLDPAWEKQQKKTFTAWCNSHLRKAGTAIDNIEEDFRNGLKLMLLLEVISGETLPKPDRGKMRFHKIANVNKALDFIASKGVHLVSIGAEEIVDGNLKMTLGMI 130

[Close]

BLAST of Actinin alpha vs. Ensembl Fly
Match: Actn (gene:FBgn0000667 transcript:FBtr0070343)

HSP 1 Score: 171.4 bits (433), Expect = 7.729e-50
Identity = 77/105 (73.33%), Postives = 90/105 (85.71%), Query Frame = 2

Query:  149 AFLDPMWELQQKKTFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
              LDP WE QQKKTFTAWCNSHLRKA   I NIE+DF +GL L+ LLE +SGE+LPKPD+G MRFHKIANVNKAL++I S+GV L+++GAEEIVDGN+KMTLGMI
Sbjct:   26 GLLDPAWEKQQKKTFTAWCNSHLRKAGTAIDNIEEDFRNGLKLMLLLEVISGETLPKPDRGKMRFHKIANVNKALDFIASKGVHLVSIGAEEIVDGNLKMTLGMI 130

[Close]

BLAST of Actinin alpha vs. Ensembl Fly
Match: Actn (gene:FBgn0000667 transcript:FBtr0303048)

HSP 1 Score: 171.4 bits (433), Expect = 7.729e-50
Identity = 77/105 (73.33%), Postives = 90/105 (85.71%), Query Frame = 2

Query:  149 AFLDPMWELQQKKTFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
              LDP WE QQKKTFTAWCNSHLRKA   I NIE+DF +GL L+ LLE +SGE+LPKPD+G MRFHKIANVNKAL++I S+GV L+++GAEEIVDGN+KMTLGMI
Sbjct:   26 GLLDPAWEKQQKKTFTAWCNSHLRKAGTAIDNIEEDFRNGLKLMLLLEVISGETLPKPDRGKMRFHKIANVNKALDFIASKGVHLVSIGAEEIVDGNLKMTLGMI 130

[Close]

BLAST of Actinin alpha vs. Ensembl Zebrafish
Match: actn3a (actinin alpha 3a [Source:ZFIN;Acc:ZDB-GENE-000329-9])

HSP 1 Score: 184.882 bits (468), Expect = 1.565e-54
Identity = 82/109 (75.23%), Postives = 96/109 (88.07%), Query Frame = 2

Query:  137 WDREAFLDPMWELQQKKTFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
            WDR+ FLDP WE QQ+KTFTAWCNSHLRKA  QI NIE+DF +GL L+ LLE +SGE LPKPDKG MRFHKIANVNKAL++I S+GV+L+++GAEEIVDGN+KMTLGMI
Sbjct:   28 WDRDLFLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPKPDKGKMRFHKIANVNKALDFISSKGVKLVSIGAEEIVDGNLKMTLGMI 136

[Close]

Query:  137 WDREAFLDPMWELQQKKTFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
            WDR+ FLDP WE QQ+KTFTAWCNSHLRKA  QI NIE+DF +GL L+ LLE +SGE LPKPDKG MRFHKIANVNKAL++I S+GV+L+++GAEEIVDGN+KMTLGMI
Sbjct:   28 WDRDLFLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPKPDKGKMRFHKIANVNKALDFISSKGVKLVSIGAEEIVDGNLKMTLGMI 136

[Close]

BLAST of Actinin alpha vs. Ensembl Zebrafish
Match: actn3a (actinin alpha 3a [Source:ZFIN;Acc:ZDB-GENE-000329-9])

HSP 1 Score: 184.496 bits (467), Expect = 2.095e-54
Identity = 82/109 (75.23%), Postives = 96/109 (88.07%), Query Frame = 2

Query:  137 WDREAFLDPMWELQQKKTFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
            WDR+ FLDP WE QQ+KTFTAWCNSHLRKA  QI NIE+DF +GL L+ LLE +SGE LPKPDKG MRFHKIANVNKAL++I S+GV+L+++GAEEIVDGN+KMTLGMI
Sbjct:   17 WDRDLFLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPKPDKGKMRFHKIANVNKALDFISSKGVKLVSIGAEEIVDGNLKMTLGMI 125

[Close]

BLAST of Actinin alpha vs. Ensembl Zebrafish
Match: actn2b (actinin, alpha 2b [Source:ZFIN;Acc:ZDB-GENE-051127-39])

HSP 1 Score: 182.185 bits (461), Expect = 1.354e-53
Identity = 81/109 (74.31%), Postives = 95/109 (87.16%), Query Frame = 2

Query:  137 WDREAFLDPMWELQQKKTFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
            WDR+  LDP WE QQ+KTFTAWCNSHLRKA  QI NIE+DF +GL L+ LLE +SGE LPKPD+G MRFHKIANVNKAL++I S+GV+L+++GAEEIVDGNVKMTLGMI
Sbjct:   27 WDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPKPDRGKMRFHKIANVNKALDFITSKGVKLVSIGAEEIVDGNVKMTLGMI 135

[Close]

BLAST of Actinin alpha vs. Ensembl Zebrafish
Match: actn2b (actinin, alpha 2b [Source:ZFIN;Acc:ZDB-GENE-051127-39])

HSP 1 Score: 182.185 bits (461), Expect = 1.404e-53
Identity = 81/109 (74.31%), Postives = 95/109 (87.16%), Query Frame = 2

Query:  137 WDREAFLDPMWELQQKKTFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
            WDR+  LDP WE QQ+KTFTAWCNSHLRKA  QI NIE+DF +GL L+ LLE +SGE LPKPD+G MRFHKIANVNKAL++I S+GV+L+++GAEEIVDGNVKMTLGMI
Sbjct:   26 WDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPKPDRGKMRFHKIANVNKALDFITSKGVKLVSIGAEEIVDGNVKMTLGMI 134

[Close]

BLAST of Actinin alpha vs. Ensembl Xenopus
Match: gss (glutathione synthetase [Source:Xenbase;Acc:XB-GENE-976512])

HSP 1 Score: 182.57 bits (462), Expect = 1.323e-53
Identity = 81/109 (74.31%), Postives = 95/109 (87.16%), Query Frame = 2

Query:  137 WDREAFLDPMWELQQKKTFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
            WDR+  LDP WE QQ+KTFTAWCNSHLRKA  QI NIE+DF +GL L+ LLE +SGE LPKPDKG MRFHKIANVNKAL++I S+GV+L+++GAEEIVDGN+KMTLGMI
Sbjct:   28 WDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPKPDKGKMRFHKIANVNKALDFIASKGVKLVSIGAEEIVDGNLKMTLGMI 136

[Close]

BLAST of Actinin alpha vs. Ensembl Xenopus
Match: gss (glutathione synthetase [Source:Xenbase;Acc:XB-GENE-976512])

HSP 1 Score: 182.185 bits (461), Expect = 1.590e-53
Identity = 81/109 (74.31%), Postives = 95/109 (87.16%), Query Frame = 2

Query:  137 WDREAFLDPMWELQQKKTFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
            WDR+  LDP WE QQ+KTFTAWCNSHLRKA  QI NIE+DF +GL L+ LLE +SGE LPKPDKG MRFHKIANVNKAL++I S+GV+L+++GAEEIVDGN+KMTLGMI
Sbjct:   28 WDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPKPDKGKMRFHKIANVNKALDFIASKGVKLVSIGAEEIVDGNLKMTLGMI 136

[Close]

BLAST of Actinin alpha vs. Ensembl Xenopus
Match: gss (glutathione synthetase [Source:Xenbase;Acc:XB-GENE-976512])

HSP 1 Score: 182.57 bits (462), Expect = 1.592e-53
Identity = 81/109 (74.31%), Postives = 95/109 (87.16%), Query Frame = 2

Query:  137 WDREAFLDPMWELQQKKTFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
            WDR+  LDP WE QQ+KTFTAWCNSHLRKA  QI NIE+DF +GL L+ LLE +SGE LPKPDKG MRFHKIANVNKAL++I S+GV+L+++GAEEIVDGN+KMTLGMI
Sbjct:   34 WDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPKPDKGKMRFHKIANVNKALDFIASKGVKLVSIGAEEIVDGNLKMTLGMI 142

[Close]

BLAST of Actinin alpha vs. Ensembl Xenopus
Match: gss (glutathione synthetase [Source:Xenbase;Acc:XB-GENE-976512])

HSP 1 Score: 182.185 bits (461), Expect = 1.801e-53
Identity = 81/109 (74.31%), Postives = 95/109 (87.16%), Query Frame = 2

Query:  137 WDREAFLDPMWELQQKKTFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
            WDR+  LDP WE QQ+KTFTAWCNSHLRKA  QI NIE+DF +GL L+ LLE +SGE LPKPDKG MRFHKIANVNKAL++I S+GV+L+++GAEEIVDGN+KMTLGMI
Sbjct:   38 WDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPKPDKGKMRFHKIANVNKALDFIASKGVKLVSIGAEEIVDGNLKMTLGMI 146

[Close]

BLAST of Actinin alpha vs. Ensembl Xenopus
Match: gss (glutathione synthetase [Source:Xenbase;Acc:XB-GENE-976512])

HSP 1 Score: 182.185 bits (461), Expect = 1.865e-53
Identity = 81/109 (74.31%), Postives = 95/109 (87.16%), Query Frame = 2

Query:  137 WDREAFLDPMWELQQKKTFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
            WDR+  LDP WE QQ+KTFTAWCNSHLRKA  QI NIE+DF +GL L+ LLE +SGE LPKPDKG MRFHKIANVNKAL++I S+GV+L+++GAEEIVDGN+KMTLGMI
Sbjct:   28 WDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPKPDKGKMRFHKIANVNKALDFIASKGVKLVSIGAEEIVDGNLKMTLGMI 136

[Close]

BLAST of Actinin alpha vs. Ensembl Mouse
Match: Actn2 (actinin alpha 2 [Source:MGI Symbol;Acc:MGI:109192])

HSP 1 Score: 183.726 bits (465), Expect = 3.743e-54
Identity = 82/109 (75.23%), Postives = 95/109 (87.16%), Query Frame = 2

Query:  137 WDREAFLDPMWELQQKKTFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
            WDR+  LDP WE QQ+KTFTAWCNSHLRKA  QI NIE+DF +GL L+ LLE +SGE LPKPD+G MRFHKIANVNKAL+YI S+GV+L+++GAEEIVDGNVKMTLGMI
Sbjct:   26 WDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPKPDRGKMRFHKIANVNKALDYIASKGVKLVSIGAEEIVDGNVKMTLGMI 134

[Close]

Query:  137 WDREAFLDPMWELQQKKTFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
            WDR+  LDP WE QQ+KTFTAWCNSHLRKA  QI NIE+DF +GL L+ LLE +SGE LPKPD+G MRFHKIANVNKAL+YI S+GV+L+++GAEEIVDGNVKMTLGMI
Sbjct:   26 WDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPKPDRGKMRFHKIANVNKALDYIASKGVKLVSIGAEEIVDGNVKMTLGMI 134

[Close]

BLAST of Actinin alpha vs. Ensembl Mouse
Match: Actn3 (actinin alpha 3 [Source:MGI Symbol;Acc:MGI:99678])

HSP 1 Score: 180.644 bits (457), Expect = 4.510e-53
Identity = 80/109 (73.39%), Postives = 95/109 (87.16%), Query Frame = 2

Query:  137 WDREAFLDPMWELQQKKTFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
            WDR+  LDP WE QQ+KTFTAWCNSHLRKA  QI NIE+DF +GL L+ LLE +SGE LP+PDKG MRFHKIANVNKAL++I S+GV+L+++GAEEIVDGN+KMTLGMI
Sbjct:   32 WDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPRPDKGKMRFHKIANVNKALDFIASKGVKLVSIGAEEIVDGNLKMTLGMI 140

[Close]

BLAST of Actinin alpha vs. Ensembl Mouse
Match: Actn1 (actinin, alpha 1 [Source:MGI Symbol;Acc:MGI:2137706])

HSP 1 Score: 172.17 bits (435), Expect = 4.562e-50
Identity = 77/109 (70.64%), Postives = 92/109 (84.40%), Query Frame = 2

Query:  137 WDREAFLDPMWELQQKKTFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
            WDR+  LDP WE QQ+KTFTAWCNSHLRKA  QI NIE+DF  GL L+ LLE +SGE L KP++G MR HKI+NVNKAL++I S+GV+L+++GAEEIVDGNVKMTLGMI
Sbjct:   19 WDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISGERLAKPERGKMRVHKISNVNKALDFIASKGVKLVSIGAEEIVDGNVKMTLGMI 127

[Close]

BLAST of Actinin alpha vs. Ensembl Mouse
Match: Actn1 (actinin, alpha 1 [Source:MGI Symbol;Acc:MGI:2137706])

HSP 1 Score: 172.17 bits (435), Expect = 5.856e-50
Identity = 77/109 (70.64%), Postives = 92/109 (84.40%), Query Frame = 2

Query:  137 WDREAFLDPMWELQQKKTFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
            WDR+  LDP WE QQ+KTFTAWCNSHLRKA  QI NIE+DF  GL L+ LLE +SGE L KP++G MR HKI+NVNKAL++I S+GV+L+++GAEEIVDGNVKMTLGMI
Sbjct:   19 WDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISGERLAKPERGKMRVHKISNVNKALDFIASKGVKLVSIGAEEIVDGNVKMTLGMI 127

[Close]

BLAST of Actinin alpha vs. UniProt/SwissProt
Match: sp|P20111|ACTN2_CHICK (Alpha-actinin-2 OS=Gallus gallus OX=9031 GN=ACTN2 PE=2 SV=1)

HSP 1 Score: 183.726 bits (465), Expect = 2.352e-53
Identity = 82/109 (75.23%), Postives = 95/109 (87.16%), Query Frame = 2

Query:  137 WDREAFLDPMWELQQKKTFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
            WDR+  LDP WE QQ+KTFTAWCNSHLRKA  QI NIE+DF +GL L+ LLE +SGE LPKPD+G MRFHKIANVNKAL+YI S+GV+L+++GAEEIVDGNVKMTLGMI
Sbjct:   29 WDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPKPDRGKMRFHKIANVNKALDYIASKGVKLVSIGAEEIVDGNVKMTLGMI 137

[Close]

BLAST of Actinin alpha vs. UniProt/SwissProt
Match: sp|Q9JI91|ACTN2_MOUSE (Alpha-actinin-2 OS=Mus musculus OX=10090 GN=Actn2 PE=1 SV=2)

HSP 1 Score: 183.726 bits (465), Expect = 2.618e-53
Identity = 82/109 (75.23%), Postives = 95/109 (87.16%), Query Frame = 2

Query:  137 WDREAFLDPMWELQQKKTFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
            WDR+  LDP WE QQ+KTFTAWCNSHLRKA  QI NIE+DF +GL L+ LLE +SGE LPKPD+G MRFHKIANVNKAL+YI S+GV+L+++GAEEIVDGNVKMTLGMI
Sbjct:   26 WDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPKPDRGKMRFHKIANVNKALDYIASKGVKLVSIGAEEIVDGNVKMTLGMI 134

[Close]

BLAST of Actinin alpha vs. UniProt/SwissProt
Match: sp|P35609|ACTN2_HUMAN (Alpha-actinin-2 OS=Homo sapiens OX=9606 GN=ACTN2 PE=1 SV=1)

HSP 1 Score: 183.726 bits (465), Expect = 2.697e-53
Identity = 82/109 (75.23%), Postives = 95/109 (87.16%), Query Frame = 2

Query:  137 WDREAFLDPMWELQQKKTFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
            WDR+  LDP WE QQ+KTFTAWCNSHLRKA  QI NIE+DF +GL L+ LLE +SGE LPKPD+G MRFHKIANVNKAL+YI S+GV+L+++GAEEIVDGNVKMTLGMI
Sbjct:   26 WDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPKPDRGKMRFHKIANVNKALDYIASKGVKLVSIGAEEIVDGNVKMTLGMI 134

[Close]

BLAST of Actinin alpha vs. UniProt/SwissProt
Match: sp|Q3ZC55|ACTN2_BOVIN (Alpha-actinin-2 OS=Bos taurus OX=9913 GN=ACTN2 PE=2 SV=1)

HSP 1 Score: 183.726 bits (465), Expect = 2.751e-53
Identity = 82/109 (75.23%), Postives = 95/109 (87.16%), Query Frame = 2

Query:  137 WDREAFLDPMWELQQKKTFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
            WDR+  LDP WE QQ+KTFTAWCNSHLRKA  QI NIE+DF +GL L+ LLE +SGE LPKPD+G MRFHKIANVNKAL+YI S+GV+L+++GAEEIVDGNVKMTLGMI
Sbjct:   26 WDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPKPDRGKMRFHKIANVNKALDYIASKGVKLVSIGAEEIVDGNVKMTLGMI 134

[Close]

BLAST of Actinin alpha vs. UniProt/SwissProt
Match: sp|Q0III9|ACTN3_BOVIN (Alpha-actinin-3 OS=Bos taurus OX=9913 GN=ACTN3 PE=2 SV=1)

HSP 1 Score: 181.03 bits (458), Expect = 2.546e-52
Identity = 80/109 (73.39%), Postives = 95/109 (87.16%), Query Frame = 2

Query:  137 WDREAFLDPMWELQQKKTFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
            WDR+  LDP WE QQ+KTFTAWCNSHLRKA  QI NIE+DF +GL L+ LLE +SGE LP+PDKG MRFHKIANVNKAL++I S+GV+L+++GAEEIVDGN+KMTLGMI
Sbjct:   33 WDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPRPDKGKMRFHKIANVNKALDFIASKGVKLVSIGAEEIVDGNLKMTLGMI 141

[Close]

BLAST of Actinin alpha vs. TrEMBL
Match: A0A2H1CG84 (Calponin-homology (CH) domain-containing protein OS=Fasciola hepatica OX=6192 GN=D915_06237 PE=4 SV=1)

HSP 1 Score: 187.193 bits (474), Expect = 6.419e-58
Identity = 85/109 (77.98%), Postives = 97/109 (88.99%), Query Frame = 2

Query:  137 WDREAFLDPMWELQQKKTFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
            WDREA+LDPMWE+QQKKTFTAWCNS+LRK    I+NIE+DF  GL LI LLETLS E LPKPD+G MRFHK+ANVNKAL YIES+GVQL+++GAEEIVDGN+KMTLGMI
Sbjct:   25 WDREAYLDPMWEIQQKKTFTAWCNSYLRKIGTSITNIEEDFQDGLKLIQLLETLSDEGLPKPDRGRMRFHKLANVNKALEYIESKGVQLVSIGAEEIVDGNIKMTLGMI 133

[Close]

BLAST of Actinin alpha vs. TrEMBL
Match: A0A494C0Q3 (Alpha-actinin-2 OS=Homo sapiens OX=9606 GN=ACTN2 PE=1 SV=1)

HSP 1 Score: 182.57 bits (462), Expect = 1.452e-56
Identity = 82/109 (75.23%), Postives = 95/109 (87.16%), Query Frame = 2

Query:  137 WDREAFLDPMWELQQKKTFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
            WDR+  LDP WE QQ+KTFTAWCNSHLRKA  QI NIE+DF +GL L+ LLE +SGE LPKPD+G MRFHKIANVNKAL+YI S+GV+L+++GAEEIVDGNVKMTLGMI
Sbjct:    7 WDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPKPDRGKMRFHKIANVNKALDYIASKGVKLVSIGAEEIVDGNVKMTLGMI 115

[Close]

BLAST of Actinin alpha vs. TrEMBL
Match: A0A2K6UAZ0 (Actinin alpha 2 OS=Saimiri boliviensis boliviensis OX=39432 GN=ACTN2 PE=4 SV=1)

HSP 1 Score: 182.185 bits (461), Expect = 4.072e-56
Identity = 82/109 (75.23%), Postives = 95/109 (87.16%), Query Frame = 2

Query:  137 WDREAFLDPMWELQQKKTFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
            WDR+  LDP WE QQ+KTFTAWCNSHLRKA  QI NIE+DF +GL L+ LLE +SGE LPKPD+G MRFHKIANVNKAL+YI S+GV+L+++GAEEIVDGNVKMTLGMI
Sbjct:   26 WDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPKPDRGKMRFHKIANVNKALDYIASKGVKLVSIGAEEIVDGNVKMTLGMI 134

[Close]

BLAST of Actinin alpha vs. TrEMBL
Match: U6DNY5 (Actinin, alpha 2 (Fragment) OS=Neovison vison OX=452646 GN=B2RCS5 PE=2 SV=1)

HSP 1 Score: 181.8 bits (460), Expect = 4.652e-56
Identity = 82/109 (75.23%), Postives = 95/109 (87.16%), Query Frame = 2

Query:  137 WDREAFLDPMWELQQKKTFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
            WDR+  LDP WE QQ+KTFTAWCNSHLRKA  QI NIE+DF +GL L+ LLE +SGE LPKPD+G MRFHKIANVNKAL+YI S+GV+L+++GAEEIVDGNVKMTLGMI
Sbjct:   26 WDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPKPDRGKMRFHKIANVNKALDYIASKGVKLVSIGAEEIVDGNVKMTLGMI 134

[Close]

BLAST of Actinin alpha vs. TrEMBL
Match: G1MYQ4 (Actinin alpha 2 OS=Meleagris gallopavo OX=9103 GN=ACTN2 PE=4 SV=2)

HSP 1 Score: 182.185 bits (461), Expect = 5.907e-56
Identity = 82/109 (75.23%), Postives = 95/109 (87.16%), Query Frame = 2

Query:  137 WDREAFLDPMWELQQKKTFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
            WDR+  LDP WE QQ+KTFTAWCNSHLRKA  QI NIE+DF +GL L+ LLE +SGE LPKPD+G MRFHKIANVNKAL+YI S+GV+L+++GAEEIVDGNVKMTLGMI
Sbjct:   19 WDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPKPDRGKMRFHKIANVNKALDYIASKGVKLVSIGAEEIVDGNVKMTLGMI 127

[Close]

BLAST of Actinin alpha vs. Ensembl Cavefish
Match: actn2b (alpha-actinin-2 [Source:NCBI gene;Acc:103024106])

HSP 1 Score: 181.8 bits (460), Expect = 1.729e-53
Identity = 81/109 (74.31%), Postives = 94/109 (86.24%), Query Frame = 2

Query:  137 WDREAFLDPMWELQQKKTFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
            WDR+  LDP WE QQ+KTFTAWCNSHLRKA  QI NIE+DF +GL L+ LLE +SGE LPKPD+G MRFHKIANVNKAL +I S+GV+L+++GAEEIVDGNVKMTLGMI
Sbjct:   28 WDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPKPDRGKMRFHKIANVNKALEFITSKGVKLVSIGAEEIVDGNVKMTLGMI 136

[Close]

BLAST of Actinin alpha vs. Ensembl Cavefish
Match: ENSAMXT00000048439.1 (pep primary_assembly:Astyanax_mexicanus-2.0:6:17687171:17747843:1 gene:ENSAMXG00000029778.1 transcript:ENSAMXT00000048439.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 180.644 bits (457), Expect = 3.350e-53
Identity = 81/109 (74.31%), Postives = 94/109 (86.24%), Query Frame = 2

Query:  137 WDREAFLDPMWELQQKKTFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
            WDR+  LDP WE QQ+KTFTAWCNSHLRKA  QI NIE++F +GL L+ LLE +SGE LPKPD+G MRFHKIANVNKAL YI S+GV+L+++GAEEIVDGNVKMTLGMI
Sbjct:   20 WDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIDNIEEEFRNGLKLMLLLEVISGERLPKPDRGKMRFHKIANVNKALEYITSKGVKLVSIGAEEIVDGNVKMTLGMI 128

[Close]

BLAST of Actinin alpha vs. Ensembl Cavefish
Match: actn4 (actinin alpha 4 [Source:NCBI gene;Acc:103022122])

HSP 1 Score: 173.326 bits (438), Expect = 1.820e-50
Identity = 77/109 (70.64%), Postives = 91/109 (83.49%), Query Frame = 2

Query:  137 WDREAFLDPMWELQQKKTFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
            WDR+  LDP WE QQ+KTFTAWCNSHLRKA  QI NIE+DF  GL L+ LLE +SGE LPKP++G MR HKI NVNKAL++I S+GV+L+++GAEEIVDGN KMTLGMI
Sbjct:   25 WDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISGERLPKPERGKMRVHKINNVNKALDFIASKGVKLVSIGAEEIVDGNAKMTLGMI 133

[Close]

BLAST of Actinin alpha vs. Ensembl Cavefish
Match: actn1 (actinin alpha 1 [Source:NCBI gene;Acc:103031817])

HSP 1 Score: 172.94 bits (437), Expect = 2.079e-50
Identity = 77/109 (70.64%), Postives = 91/109 (83.49%), Query Frame = 2

Query:  137 WDREAFLDPMWELQQKKTFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
            WDR+  LDP WE QQ+KTFTAWCNSHLRKA  QI NIE+DF  GL L+ LLE +SGE L KP++G MR HKI+NVNKALN+I S+GV+L+++GAEEIVDGN KMTLGMI
Sbjct:   28 WDRDMLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISGERLAKPERGKMRVHKISNVNKALNFITSKGVKLVSIGAEEIVDGNAKMTLGMI 136

[Close]

BLAST of Actinin alpha vs. Ensembl Cavefish
Match: actn1 (actinin alpha 1 [Source:NCBI gene;Acc:103031817])

HSP 1 Score: 172.94 bits (437), Expect = 2.156e-50
Identity = 77/109 (70.64%), Postives = 91/109 (83.49%), Query Frame = 2

Query:  137 WDREAFLDPMWELQQKKTFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
            WDR+  LDP WE QQ+KTFTAWCNSHLRKA  QI NIE+DF  GL L+ LLE +SGE L KP++G MR HKI+NVNKALN+I S+GV+L+++GAEEIVDGN KMTLGMI
Sbjct:   28 WDRDMLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISGERLAKPERGKMRVHKISNVNKALNFITSKGVKLVSIGAEEIVDGNAKMTLGMI 136

[Close]

BLAST of Actinin alpha vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000684.1 (pep scaffold:Pmarinus_7.0:GL483163:49540:93186:-1 gene:ENSPMAG00000000623.1 transcript:ENSPMAT00000000684.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 140.584 bits (353), Expect = 1.642e-40
Identity = 64/93 (68.82%), Postives = 78/93 (83.87%), Query Frame = 2

Query:  185 KTFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
            +TFTAWCNSHLRKA  QI +I++DF  GL L+ LLE +S E LPKP+KG MR HKI NVNKAL++I S+GV+L+++GAEEIVDGN KMTLGMI
Sbjct:    4 QTFTAWCNSHLRKAGTQIDSIDEDFRDGLKLMLLLEVISSERLPKPEKGKMRVHKINNVNKALDFIASKGVKLVSIGAEEIVDGNTKMTLGMI 96

[Close]

BLAST of Actinin alpha vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009295.1 (pep scaffold:Pmarinus_7.0:GL479988:2885:20778:1 gene:ENSPMAG00000008383.1 transcript:ENSPMAT00000009295.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 140.584 bits (353), Expect = 1.070e-39
Identity = 63/92 (68.48%), Postives = 78/92 (84.78%), Query Frame = 2

Query:  188 TFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
            TFTAWCNSHLRKA   I NI++DF +GL L+ LLE +SGE L KP++G MR HKI+NVNKAL++I S+GV+L+++GAEEIVDGN KMTLGMI
Sbjct:    1 TFTAWCNSHLRKAGTGIENIDEDFRNGLKLMLLLEVISGERLAKPERGKMRVHKISNVNKALDFIASKGVKLVSIGAEEIVDGNAKMTLGMI 92

[Close]

BLAST of Actinin alpha vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004049.1 (pep scaffold:Pmarinus_7.0:GL476488:489896:554954:1 gene:ENSPMAG00000003699.1 transcript:ENSPMAT00000004049.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 105.916 bits (263), Expect = 1.305e-27
Identity = 50/95 (52.63%), Postives = 66/95 (69.47%), Query Frame = 2

Query:  179 QKKTFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
            QKKTFT W NSHL + + +I ++  D   G  LI LLE LSGE LPKP KG MR H + NV KAL +++ + V L N+G+ +IVDGN ++TLG+I
Sbjct:    8 QKKTFTKWVNSHLSRVSCRIGDLYADLRDGRMLIKLLEVLSGERLPKPTKGKMRIHCLENVEKALQFLKEQRVHLENMGSHDIVDGNHRLTLGLI 102

[Close]

BLAST of Actinin alpha vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008111.1 (pep scaffold:Pmarinus_7.0:GL478136:8967:48859:1 gene:ENSPMAG00000007298.1 transcript:ENSPMAT00000008111.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 103.219 bits (256), Expect = 1.213e-26
Identity = 49/98 (50.00%), Postives = 68/98 (69.39%), Query Frame = 2

Query:  170 ELQQKKTFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
            E  QKKTFT W NSHL + + +I+++  D   G  LI LLE LSGE LPKP +G MR H + NV+KAL +++ + V L N+G+ +IVDGN ++ LG+I
Sbjct:   56 EAVQKKTFTKWVNSHLARVSCRITDLYTDLRDGRMLIKLLEVLSGEKLPKPTRGKMRIHCLENVDKALQFLKEQKVHLENMGSHDIVDGNHRLILGLI 153

[Close]

BLAST of Actinin alpha vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002838.1 (pep scaffold:Pmarinus_7.0:GL477168:22072:87306:1 gene:ENSPMAG00000002584.1 transcript:ENSPMAT00000002838.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 101.293 bits (251), Expect = 5.366e-26
Identity = 47/95 (49.47%), Postives = 68/95 (71.58%), Query Frame = 2

Query:  179 QKKTFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
            QKKTFT W N HL K    ++++ +D   G NLI LLE LSGE LP+ +KG MRFH++ NV  AL+++  R ++L+N+ +++I DGN K+TLG+I
Sbjct:   12 QKKTFTKWVNKHLMKVRKHVNDMYEDLRDGHNLISLLEVLSGEKLPR-EKGRMRFHRLHNVQIALDFLRLRQIKLVNIRSDDIADGNPKLTLGLI 105

[Close]

BLAST of Actinin alpha vs. Ensembl Nematostella
Match: ALPHA-ACTININ (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4X0])

HSP 1 Score: 155.606 bits (392), Expect = 1.111e-44
Identity = 69/105 (65.71%), Postives = 85/105 (80.95%), Query Frame = 2

Query:  149 AFLDPMWELQQKKTFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
              LDP WE QQKKTFTAWCNSHLRK   QI  IE+D   G+ L+ LLE +SGE LP P++G +RFH+IANVNKAL+++  +GV+L++VGAEEIVDGN+KMTLGMI
Sbjct:   19 GLLDPAWERQQKKTFTAWCNSHLRKTGKQIGEIEEDLRDGVLLLQLLEIISGERLPHPERGKLRFHRIANVNKALDFVAGKGVKLVSVGAEEIVDGNLKMTLGMI 123

[Close]

BLAST of Actinin alpha vs. Ensembl Nematostella
Match: EDO42431 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S1C0])

HSP 1 Score: 108.227 bits (269), Expect = 4.679e-28
Identity = 52/98 (53.06%), Postives = 67/98 (68.37%), Query Frame = 2

Query:  170 ELQQKKTFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
            E  QKKTFT W NSHL++   +++ +  D   G  LI LLE LSGE LPKP KG MR H + NV K+L +++ + V L NVGA +IVDGN K+TLG+I
Sbjct:   23 ERVQKKTFTKWINSHLQRVGARVNELYHDLQDGRKLILLLEVLSGEKLPKPSKGRMRIHNLENVEKSLVFLKKQRVHLENVGAHDIVDGNQKITLGLI 120

[Close]

BLAST of Actinin alpha vs. Ensembl Nematostella
Match: EDO46947 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RNL3])

HSP 1 Score: 90.5077 bits (223), Expect = 6.141e-22
Identity = 43/103 (41.75%), Postives = 66/103 (64.08%), Query Frame = 2

Query:  158 DPMWELQQKKTFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNM-RFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
            D  W+  Q+ TFT WCN HL+     + ++E D C GL LI LL+ LS + LP+ +K  + +  KI NV+ +L +IE   ++L+N+ A +IV GN+K+ LG+I
Sbjct:  360 DAEWKKIQQNTFTRWCNEHLKCVKQFVYSLETDLCDGLKLIALLQVLSQKRLPRFNKKPVFKSQKIENVSISLKFIEDENIRLVNIDASDIVKGNLKLILGLI 462

[Close]

BLAST of Actinin alpha vs. Ensembl Nematostella
Match: EDO49576 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGP7])

HSP 1 Score: 89.7373 bits (221), Expect = 1.015e-21
Identity = 43/97 (44.33%), Postives = 65/97 (67.01%), Query Frame = 2

Query:  173 LQQKKTFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
              QKKTFT W NS L K+ + ++++ +D   G  LI LLE +SGE +    +G  R H I NVNKAL +++ + V+L ++GAE++VDGN ++ LG+I
Sbjct:   23 FSQKKTFTKWVNSFLDKSGLHVNDLFEDLADGKILISLLEIISGEKIGFAARGKFRVHNIQNVNKALEFLQ-KSVKLESIGAEDVVDGNERLILGLI 118

[Close]

BLAST of Actinin alpha vs. Ensembl Nematostella
Match: EDO41099 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S5D1])

HSP 1 Score: 87.4261 bits (215), Expect = 7.423e-21
Identity = 46/100 (46.00%), Postives = 65/100 (65.00%), Query Frame = 2

Query:  170 ELQQKKTFTAWCNSHLRKA--NIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
            E  QKKTFT W N  L +A  N+++ ++  D   G  LI LLE L+G+ + K ++GNMR H + NVN A+  +E   ++LIN+   +IVDGN KMTLG+I
Sbjct:    5 EGTQKKTFTKWINIQLSRAGNNVRVGDLFNDLKDGTILIALLEVLTGKKI-KRERGNMRLHHLNNVNNAMMILEENDIRLINISNNDIVDGNHKMTLGLI 103

[Close]

BLAST of Actinin alpha vs. Ensembl Medaka
Match: actn2b (alpha-actinin-2 [Source:NCBI gene;Acc:101164086])

HSP 1 Score: 181.03 bits (458), Expect = 2.470e-53
Identity = 81/109 (74.31%), Postives = 93/109 (85.32%), Query Frame = 2

Query:  137 WDREAFLDPMWELQQKKTFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
            WDR+  LDP WE QQ+KTFTAWCNSHLRKA  QI NIE DF +GL L+ LLE +SGE LPKPD+G MRFHKIANVNKAL +I S+GV+L+++GAEEIVDGNVKMTLGMI
Sbjct:   27 WDRDMLLDPAWEQQQRKTFTAWCNSHLRKAGTQIENIEDDFRNGLKLMLLLEVISGERLPKPDRGKMRFHKIANVNKALEFITSKGVKLVSIGAEEIVDGNVKMTLGMI 135

[Close]

BLAST of Actinin alpha vs. Ensembl Medaka
Match: ENSORLT00000001153.2 (alpha-actinin-4 [Source:NCBI gene;Acc:101155449])

HSP 1 Score: 174.481 bits (441), Expect = 5.851e-51
Identity = 77/109 (70.64%), Postives = 92/109 (84.40%), Query Frame = 2

Query:  137 WDREAFLDPMWELQQKKTFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
            WDR+  LDP WE QQ+KTFTAWCNSHLRKA  QI NIE+DF  GL L+ LLE +SGE LPKP++G MR HKI NVNKAL++I S+GV+L+++GAEEIVDGN+KMTLGMI
Sbjct:   25 WDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISGERLPKPERGKMRVHKINNVNKALDFIASKGVKLVSIGAEEIVDGNIKMTLGMI 133

[Close]

BLAST of Actinin alpha vs. Ensembl Medaka
Match: ENSORLT00000001155.2 (alpha-actinin-4 [Source:NCBI gene;Acc:101155449])

HSP 1 Score: 174.481 bits (441), Expect = 6.518e-51
Identity = 77/109 (70.64%), Postives = 92/109 (84.40%), Query Frame = 2

Query:  137 WDREAFLDPMWELQQKKTFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
            WDR+  LDP WE QQ+KTFTAWCNSHLRKA  QI NIE+DF  GL L+ LLE +SGE LPKP++G MR HKI NVNKAL++I S+GV+L+++GAEEIVDGN+KMTLGMI
Sbjct:   25 WDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISGERLPKPERGKMRVHKINNVNKALDFIASKGVKLVSIGAEEIVDGNIKMTLGMI 133

[Close]

BLAST of Actinin alpha vs. Ensembl Medaka
Match: ENSORLT00000027622.1 (alpha-actinin-4 [Source:NCBI gene;Acc:101155449])

HSP 1 Score: 174.481 bits (441), Expect = 7.263e-51
Identity = 77/109 (70.64%), Postives = 92/109 (84.40%), Query Frame = 2

Query:  137 WDREAFLDPMWELQQKKTFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
            WDR+  LDP WE QQ+KTFTAWCNSHLRKA  QI NIE+DF  GL L+ LLE +SGE LPKP++G MR HKI NVNKAL++I S+GV+L+++GAEEIVDGN+KMTLGMI
Sbjct:   25 WDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISGERLPKPERGKMRVHKINNVNKALDFIASKGVKLVSIGAEEIVDGNIKMTLGMI 133

[Close]

BLAST of Actinin alpha vs. Ensembl Medaka
Match: ENSORLT00000001151.2 (alpha-actinin-4 [Source:NCBI gene;Acc:101155449])

HSP 1 Score: 174.096 bits (440), Expect = 7.580e-51
Identity = 77/109 (70.64%), Postives = 92/109 (84.40%), Query Frame = 2

Query:  137 WDREAFLDPMWELQQKKTFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
            WDR+  LDP WE QQ+KTFTAWCNSHLRKA  QI NIE+DF  GL L+ LLE +SGE LPKP++G MR HKI NVNKAL++I S+GV+L+++GAEEIVDGN+KMTLGMI
Sbjct:   25 WDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISGERLPKPERGKMRVHKINNVNKALDFIASKGVKLVSIGAEEIVDGNIKMTLGMI 133

[Close]

BLAST of Actinin alpha vs. Planmine SMEST
Match: SMESG000040562.1 (SMESG000040562.1)

HSP 1 Score: 258.455 bits (659), Expect = 8.732e-82
Identity = 137/137 (100.00%), Postives = 137/137 (100.00%), Query Frame = 2

Query:   53 MIYYPVKDQYVNCVXXXXXXXXXXXXXXWDREAFLDPMWELQQKKTFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
            MIYYPVKDQYVNCVEEENNAGAEEEEEEWDREAFLDPMWELQQKKTFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI
Sbjct:    1 MIYYPVKDQYVNCVEEENNAGAEEEEEEWDREAFLDPMWELQQKKTFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 137

[Close]

BLAST of Actinin alpha vs. Planmine SMEST
Match: SMESG000074430.1 (SMESG000074430.1)

HSP 1 Score: 159.073 bits (401), Expect = 1.406e-45
Identity = 71/103 (68.93%), Postives = 87/103 (84.47%), Query Frame = 2

Query:  155 LDPMWELQQKKTFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
            +DP+WE QQ  TFTAWCN+HLRKA+++I N E+DF  GL L+ LLE +S ++LP PDKG MRFHKIANVNKAL +IE +GV+L ++GAEEIVDGNVKMTLGMI
Sbjct:   46 IDPIWEAQQISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMI 148

[Close]

BLAST of Actinin alpha vs. Planmine SMEST
Match: SMESG000074430.1 (SMESG000074430.1)

HSP 1 Score: 158.688 bits (400), Expect = 1.671e-45
Identity = 71/103 (68.93%), Postives = 87/103 (84.47%), Query Frame = 2

Query:  155 LDPMWELQQKKTFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
            +DP+WE QQ  TFTAWCN+HLRKA+++I N E+DF  GL L+ LLE +S ++LP PDKG MRFHKIANVNKAL +IE +GV+L ++GAEEIVDGNVKMTLGMI
Sbjct:   46 IDPIWEAQQISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMI 148

[Close]

BLAST of Actinin alpha vs. Planmine SMEST
Match: SMESG000047739.1 (SMESG000047739.1)

HSP 1 Score: 154.836 bits (390), Expect = 3.758e-44
Identity = 73/103 (70.87%), Postives = 84/103 (81.55%), Query Frame = 2

Query:  155 LDPMWELQQKKTFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
            ++ +WE QQK TFTAWCNSHLRK N  IS I +DF  GLNL+ LLE +SGESLPKPDKG MR HKIANVNK L +I+ +GV+L+ V AEEIVDGNVKMTLGMI
Sbjct:   25 IEQLWEKQQKSTFTAWCNSHLRKVNTAISVIGEDFRDGLNLMKLLEVISGESLPKPDKGKMRVHKIANVNKCLQFIQEKGVKLVLVAAEEIVDGNVKMTLGMI 127

[Close]

BLAST of Actinin alpha vs. Planmine SMEST
Match: SMESG000074430.1 (SMESG000074430.1)

HSP 1 Score: 154.066 bits (388), Expect = 6.444e-44
Identity = 70/99 (70.71%), Postives = 84/99 (84.85%), Query Frame = 2

Query:  167 WELQQKKTFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLSGESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMTLGMI 463
            WE QQK TFTAWCN+HLRKA+++I N E+DF  GL L+ LLE +S ++LP PDKG MRFHKIANVNKAL +IE +GV+L ++GAEEIVDGNVKMTLGMI
Sbjct:   18 WEKQQKVTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMI 116

The following BLAST results are available for this feature:

BLAST of Actinin alpha vs. Ensembl Human
BLAST of Actinin alpha vs. Ensembl Celegans
BLAST of Actinin alpha vs. Ensembl Fly
BLAST of Actinin alpha vs. Ensembl Zebrafish
BLAST of Actinin alpha vs. Ensembl Xenopus
BLAST of Actinin alpha vs. Ensembl Mouse
BLAST of Actinin alpha vs. UniProt/SwissProt
BLAST of Actinin alpha vs. TrEMBL
BLAST of Actinin alpha vs. Ensembl Cavefish
BLAST of Actinin alpha vs. Ensembl Sea Lamprey
BLAST of Actinin alpha vs. Ensembl Yeast
BLAST of Actinin alpha vs. Ensembl Nematostella
BLAST of Actinin alpha vs. Ensembl Medaka
BLAST of Actinin alpha vs. Planmine SMEST

BLAST of Actinin alpha vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ACTN2	1.020e-59	75.23	actinin alpha 2 [Source:HGNC Symbol;Acc:HGNC:164]	[more]
ACTN2	1.180e-58	75.23	actinin alpha 2 [Source:HGNC Symbol;Acc:HGNC:164]	[more]
ACTN2	1.759e-57	75.23	actinin alpha 2 [Source:HGNC Symbol;Acc:HGNC:164]	[more]
ACTN2	5.176e-54	75.23	actinin alpha 2 [Source:HGNC Symbol;Acc:HGNC:164]	[more]
ACTN2	5.616e-54	75.23	actinin alpha 2 [Source:HGNC Symbol;Acc:HGNC:164]	[more]

BLAST of Actinin alpha vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
atn-1	1.155e-53	75.23	AcTiniN [Source:UniProtKB/TrEMBL;Acc:Q9XVU8]	[more]
atn-1	1.224e-53	75.23	AcTiniN [Source:UniProtKB/TrEMBL;Acc:Q9XVU8]	[more]
atn-1	1.547e-27	77.42	AcTiniN [Source:UniProtKB/TrEMBL;Acc:Q9XVU8]	[more]
atn-1	2.599e-27	77.42	AcTiniN [Source:UniProtKB/TrEMBL;Acc:Q9XVU8]	[more]
sma-1	6.154e-26	46.32	SMAll [Source:UniProtKB/TrEMBL;Acc:G5EFW3]	[more]

BLAST of Actinin alpha vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Actn	7.394e-50	73.33	gene:FBgn0000667 transcript:FBtr0310657	[more]
Actn	7.653e-50	73.33	gene:FBgn0000667 transcript:FBtr0070344	[more]
Actn	7.729e-50	73.33	gene:FBgn0000667 transcript:FBtr0333801	[more]
Actn	7.729e-50	73.33	gene:FBgn0000667 transcript:FBtr0070343	[more]
Actn	7.729e-50	73.33	gene:FBgn0000667 transcript:FBtr0303048	[more]

BLAST of Actinin alpha vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
actn3a	1.565e-54	75.23	actinin alpha 3a [Source:ZFIN;Acc:ZDB-GENE-000329-...	[more]
actn3a	1.565e-54	75.23	actinin alpha 3a [Source:ZFIN;Acc:ZDB-GENE-000329-...	[more]
actn3a	2.095e-54	75.23	actinin alpha 3a [Source:ZFIN;Acc:ZDB-GENE-000329-...	[more]
actn2b	1.354e-53	74.31	actinin, alpha 2b [Source:ZFIN;Acc:ZDB-GENE-051127...	[more]
actn2b	1.404e-53	74.31	actinin, alpha 2b [Source:ZFIN;Acc:ZDB-GENE-051127...	[more]

BLAST of Actinin alpha vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
gss	1.323e-53	74.31	glutathione synthetase [Source:Xenbase;Acc:XB-GENE...	[more]
gss	1.590e-53	74.31	glutathione synthetase [Source:Xenbase;Acc:XB-GENE...	[more]
gss	1.592e-53	74.31	glutathione synthetase [Source:Xenbase;Acc:XB-GENE...	[more]
gss	1.801e-53	74.31	glutathione synthetase [Source:Xenbase;Acc:XB-GENE...	[more]
gss	1.865e-53	74.31	glutathione synthetase [Source:Xenbase;Acc:XB-GENE...	[more]

BLAST of Actinin alpha vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Actn2	3.743e-54	75.23	actinin alpha 2 [Source:MGI Symbol;Acc:MGI:109192]	[more]
Actn2	3.743e-54	75.23	actinin alpha 2 [Source:MGI Symbol;Acc:MGI:109192]	[more]
Actn3	4.510e-53	73.39	actinin alpha 3 [Source:MGI Symbol;Acc:MGI:99678]	[more]
Actn1	4.562e-50	70.64	actinin, alpha 1 [Source:MGI Symbol;Acc:MGI:213770...	[more]
Actn1	5.856e-50	70.64	actinin, alpha 1 [Source:MGI Symbol;Acc:MGI:213770...	[more]

BLAST of Actinin alpha vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|P20111\|ACTN2_CHICK	2.352e-53	75.23	Alpha-actinin-2 OS=Gallus gallus OX=9031 GN=ACTN2 ...	[more]
sp\|Q9JI91\|ACTN2_MOUSE	2.618e-53	75.23	Alpha-actinin-2 OS=Mus musculus OX=10090 GN=Actn2 ...	[more]
sp\|P35609\|ACTN2_HUMAN	2.697e-53	75.23	Alpha-actinin-2 OS=Homo sapiens OX=9606 GN=ACTN2 P...	[more]
sp\|Q3ZC55\|ACTN2_BOVIN	2.751e-53	75.23	Alpha-actinin-2 OS=Bos taurus OX=9913 GN=ACTN2 PE=...	[more]
sp\|Q0III9\|ACTN3_BOVIN	2.546e-52	73.39	Alpha-actinin-3 OS=Bos taurus OX=9913 GN=ACTN3 PE=...	[more]

BLAST of Actinin alpha vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A2H1CG84	6.419e-58	77.98	Calponin-homology (CH) domain-containing protein O...	[more]
A0A494C0Q3	1.452e-56	75.23	Alpha-actinin-2 OS=Homo sapiens OX=9606 GN=ACTN2 P...	[more]
A0A2K6UAZ0	4.072e-56	75.23	Actinin alpha 2 OS=Saimiri boliviensis boliviensis...	[more]
U6DNY5	4.652e-56	75.23	Actinin, alpha 2 (Fragment) OS=Neovison vison OX=4...	[more]
G1MYQ4	5.907e-56	75.23	Actinin alpha 2 OS=Meleagris gallopavo OX=9103 GN=...	[more]

BLAST of Actinin alpha vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
actn2b	1.729e-53	74.31	alpha-actinin-2 [Source:NCBI gene;Acc:103024106]	[more]
ENSAMXT00000048439.1	3.350e-53	74.31	pep primary_assembly:Astyanax_mexicanus-2.0:6:1768...	[more]
actn4	1.820e-50	70.64	actinin alpha 4 [Source:NCBI gene;Acc:103022122]	[more]
actn1	2.079e-50	70.64	actinin alpha 1 [Source:NCBI gene;Acc:103031817]	[more]
actn1	2.156e-50	70.64	actinin alpha 1 [Source:NCBI gene;Acc:103031817]	[more]

BLAST of Actinin alpha vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSPMAT00000000684.1	1.642e-40	68.82	pep scaffold:Pmarinus_7.0:GL483163:49540:93186:-1 ...	[more]
ENSPMAT00000009295.1	1.070e-39	68.48	pep scaffold:Pmarinus_7.0:GL479988:2885:20778:1 ge...	[more]
ENSPMAT00000004049.1	1.305e-27	52.63	pep scaffold:Pmarinus_7.0:GL476488:489896:554954:1...	[more]
ENSPMAT00000008111.1	1.213e-26	50.00	pep scaffold:Pmarinus_7.0:GL478136:8967:48859:1 ge...	[more]
ENSPMAT00000002838.1	5.366e-26	49.47	pep scaffold:Pmarinus_7.0:GL477168:22072:87306:1 g...	[more]

BLAST of Actinin alpha vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Actinin alpha vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
ALPHA-ACTININ	1.111e-44	65.71	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO42431	4.679e-28	53.06	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO46947	6.141e-22	41.75	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO49576	1.015e-21	44.33	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO41099	7.423e-21	46.00	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Actinin alpha vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
actn2b	2.470e-53	74.31	alpha-actinin-2 [Source:NCBI gene;Acc:101164086]	[more]
ENSORLT00000001153.2	5.851e-51	70.64	alpha-actinin-4 [Source:NCBI gene;Acc:101155449]	[more]
ENSORLT00000001155.2	6.518e-51	70.64	alpha-actinin-4 [Source:NCBI gene;Acc:101155449]	[more]
ENSORLT00000027622.1	7.263e-51	70.64	alpha-actinin-4 [Source:NCBI gene;Acc:101155449]	[more]
ENSORLT00000001151.2	7.580e-51	70.64	alpha-actinin-4 [Source:NCBI gene;Acc:101155449]	[more]

BLAST of Actinin alpha vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000040562.1	8.732e-82	100.00	SMESG000040562.1	[more]
SMESG000074430.1	1.406e-45	68.93	SMESG000074430.1	[more]
SMESG000074430.1	1.671e-45	68.93	SMESG000074430.1	[more]
SMESG000047739.1	3.758e-44	70.87	SMESG000047739.1	[more]
SMESG000074430.1	6.444e-44	70.71	SMESG000074430.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30020038 ID=SMED30020038|Name=Actinin alpha|organism=Schmidtea mediterranea sexual|type=transcript|length=463bp
GCAGCCTTTATTTAAATATTTAATTTACATATCGTGCAGTAATTTACGAT
TTATGATTTATTATCCTGTTAAAGATCAATACGTTAATTGTGTTGAAGAA
GAAAATAATGCTGGAGCAGAGGAAGAAGAAGAAGAATGGGATCGTGAAGC
TTTTCTTGATCCAATGTGGGAACTCCAACAAAAAAAAACATTTACTGCAT
GGTGTAATTCTCATTTAAGAAAAGCTAATATTCAAATTTCAAATATCGAA
CAGGATTTTTGTCATGGTCTAAATTTAATTTATTTGTTGGAAACTTTATC
AGGAGAATCTTTACCGAAACCTGACAAAGGAAATATGAGATTCCACAAAA
TTGCAAATGTCAATAAAGCTTTGAATTATATCGAAAGTCGAGGAGTGCAA
TTAATTAATGTAGGAGCAGAAGAAATTGTTGATGGAAACGTTAAAATGAC
TCTTGGAATGATT

protein sequence of SMED30020038-orf-1

>SMED30020038-orf-1 ID=SMED30020038-orf-1|Name=SMED30020038-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=154bp
QPLFKYLIYISCSNLRFMIYYPVKDQYVNCVEEENNAGAEEEEEEWDREA
FLDPMWELQQKKTFTAWCNSHLRKANIQISNIEQDFCHGLNLIYLLETLS
GESLPKPDKGNMRFHKIANVNKALNYIESRGVQLINVGAEEIVDGNVKMT
LGMI

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000101	muscle cell

Vocabulary: **INTERPRO**
Term	Definition
IPR036872	CH_dom_sf
IPR001715	CH-domain
IPR001589	Actinin_actin-bd_CS

Vocabulary: **molecular function**
Term	Definition
GO:0005515	protein binding
GO:0003779	actin binding
GO:0005509	calcium ion binding
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
GO:0008092	cytoskeletal protein binding
GO:0019904	protein domain specific binding
GO:0030274	LIM domain binding
GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
GO:0030375	thyroid hormone receptor coactivator activity
GO:0030674	protein binding, bridging
GO:0031432	titin binding
GO:0042802	identical protein binding
GO:0042803	protein homodimerization activity
GO:0044325	ion channel binding
GO:0046872	metal ion binding
GO:0046983	protein dimerization activity
GO:0051015	actin filament binding
GO:0051373	FATZ binding
GO:0070080	titin Z domain binding

Vocabulary: **cellular component**
Term	Definition
GO:0005737	cytoplasm
GO:0005865	striated muscle thin filament
GO:0005886	plasma membrane
GO:0005925	focal adhesion
GO:0030017	sarcomere
GO:0030018	Z disc
GO:0030175	filopodium
GO:0030864	cortical actin cytoskeleton
GO:0070062	extracellular exosome

Vocabulary: **biological process**
Term	Definition
GO:0006936	muscle contraction
GO:0030035	microspike assembly
GO:0042391	regulation of membrane potential
GO:0043267	negative regulation of potassium ion transport
GO:0043268	positive regulation of potassium ion transport
GO:0045214	sarcomere organization
GO:0048041	focal adhesion assembly
GO:0051289	protein homotetramerization
GO:0051695	actin filament uncapping
GO:0055013	cardiac muscle cell development
GO:0086097	phospholipase C-activating angiotensin-activated signaling pathway
GO:0090002	establishment of protein localization to plasma membrane
GO:1901017	negative regulation of potassium ion transmembrane transporter activity
GO:1901018	positive regulation of potassium ion transmembrane transporter activity
GO:1903506	regulation of nucleic acid-templated transcription
GO:2000009	negative regulation of protein localization to cell surface
GO:2000273	positive regulation of signaling receptor activity
GO:2001137	positive regulation of endocytic recycling
GO:2001259	positive regulation of cation channel activity

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR001715	Calponin homology domain	SMART	SM00033	ch_5	coord: 60..154 e-value: 3.7E-13 score: 59.7
IPR001715	Calponin homology domain	PFAM	PF00307	CH	coord: 59..154 e-value: 3.6E-20 score: 72.2
IPR001715	Calponin homology domain	PROSITE	PS50021	CH	coord: 58..154 score: 22.227
IPR001715	Calponin homology domain	CDD	cd00014	CH	coord: 60..154 e-value: 6.85557E-20 score: 77.3511
IPR036872	CH domain superfamily	GENE3D	G3DSA:1.10.418.10		coord: 40..154 e-value: 1.7E-37 score: 130.0
IPR036872	CH domain superfamily	SUPERFAMILY	SSF47576	Calponin-homology domain, CH-domain	coord: 42..154
None	No IPR available	PANTHER	PTHR23167:SF22	ALPHA-ACTININ-2	coord: 40..154
None	No IPR available	PANTHER	PTHR23167	FAMILY NOT NAMED	coord: 40..154
IPR001589	Actinin-type actin-binding domain, conserved site	PROSITE	PS00019	ACTININ_1	coord: 60..69

Main menu

Actinin alpha

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 10

Owlery

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