DNA polymerase subunit gamma
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30020035 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 9
Homology
BLAST of DNA polymerase subunit gamma vs. Ensembl Human
Match: POLG (DNA polymerase gamma, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9179]) HSP 1 Score: 429.869 bits (1104), Expect = 5.077e-130 Identity = 230/489 (47.03%), Postives = 288/489 (58.90%), Query Frame = 3
Query: 2118 IPFVWFLPLPHEKGEGNTVGSPFSKSFLNYMQSGRLTSHAANNLLEIMIEGKKSGVFWRNYQNRVQSQFMV---RTS------------KENNESAIIPQVIVAGTVTRRSVERLWLTATNSTNDRVGSELKAMVQTPTNWVMVGADVDSQEQWIAAVLGDS-VTGIHGGTPFGWMVLQGSKVDGTDLHSKTSKMIGISRNAAKVLNYSRMYGAGIKSSTDTLLKYNPELKPQEAFNKIKDLMKQTKG---------------------KRSQGKWVD------------------------------GIESEVFSKLEEIAKSDEPSTPVLNARLSQALEKRVVNEKFMTSKCNWVVQSSGVDYLHCLLTFTKHLIQLYNVNARLCICIHDEIRYLCEEKDKYRLALILQIANLYTRSVFSMKLNLFDLPQSIAFFSEIDIDYCLRKSPTDDCITPSNQNGLLNNYNIQKGESLNIYQILDKTGGRLD 3383
IP WF LPH+ G VGSPF+K FL M+ G L + +E K FWRN R+ SQ +V R++ +E AI+PQV+ AGT+TRR+VE WLTA+N+ DRVGSELKAMVQ P + +VGADVDSQE WIAAVLGD+ G+HG T FGWM LQG K GTDLHSKT+ +GISR AK+ NY R+YGAG + L+++N L QEA K + + TKG R++G W+ G ESE+F+KLE IA SD P TPVL +S+ALE V E+FMTS+ NWVVQSS VDYLH +L K L + + ++ R CI IHDE+RYL E+D+YR AL LQI NL TR +F+ KL L DLPQS+AFFS +DID CLRK T DC TPSN G+ Y I +GE+L+IYQI++ T G L+
Sbjct: 744 IPGCWFFKLPHKDGNSCNVGSPFAKDFLPKMEDGTLQAGPGGASGPRALEINKMISFWRNAHKRISSQMVVWLPRSALPRAVIRHPDYDEEGLYGAILPQVVTAGTITRRAVEPTWLTASNARPDRVGSELKAMVQAPPGYTLVGADVDSQELWIAAVLGDAHFAGMHGCTAFGWMTLQGRKSRGTDLHSKTATTVGISREHAKIFNYGRIYGAGQPFAERLLMQFNHRLTQQEAAEKAQQMYAATKGLRWYRLSDEGEWLVRELNLPVDRTEGGWISLQDLRKVQRETARKSQWKKWEVVAERAWKGGTESEMFNKLESIATSDIPRTPVLGCCISRALEPSAVQEEFMTSRVNWVVQSSAVDYLHLMLVAMKWLFEEFAIDGRFCISIHDEVRYLVREEDRYRAALALQITNLLTRCMFAYKLGLNDLPQSVAFFSAVDIDRCLRKEVTMDCKTPSNPTGMERRYGIPQGEALDIYQIIELTKGSLE 1232 HSP 2 Score: 275.404 bits (703), Expect = 1.443e-75 Identity = 160/435 (36.78%), Postives = 232/435 (53.33%), Query Frame = 3
Query: 204 NSSDDKLRINMMNIQMINKKFQETIFGSKS--TAELDFFEINSLFKNFKIDTEKTTLNKNVDFDLPPLLGENIEIHLQKAAETLNDPYMALLKGLDDWKIPQMPTMWSFQEGWTKYDTINNKFYKVSVPEENLLIFDVETLPKYTQRAVMAVAVGKSYWYSWTSKYLLDGICKDDSEICKDDLIPLYSNDDKSKP-------KCIVGHFVSFDRARIRDEYCIKGTGTRFIDTMSMQIAIRGMTSLQRSLKISFNNNNTENRIWKLYFSNSSKNGMNNSPEDIEESDKWLTEASLNSLVDVYQYYFPNCNLSSLKDKRETFIKGTIDDIVNDFQALMTYCATDVIMTAKIFQKLWTDYRVRFPHPASFTGMLEMGSLYLPVNSNLNTYINRASTTYESMIKKEKEILMELAQKS--LASKEKEYINDPWLWDLDW 1475
+S +LR N ++IQM+++ E IFG E + + + +V+ LPPL G+N++ H + A+ + PY+ L ++P P W++ EGWT+Y + V++PEE L+FDVE +AVA+ S WYSW S+ L++ S++ DLIPL S P + +VGH VSFDRA IR++Y I+G+ RF+DTMSM +AI G++S QRSL I+ + + S + I D WL +S+NSL +V++ Y L K+ RE F+KGT+ DI +FQ LM YCA DV T ++FQ+ + R PHP + GMLEMG YLPVN N Y+ A TYE + ++ K+ LM+LA + L S E+ Y DPWLWDL+W
Sbjct: 63 SSEGGQLRHNPLDIQMLSRGLHEQIFGQGGEMPGEAAVRRSVEHLQKHGLWGQPAVPLPDVELRLPPLYGDNLDQHFRLLAQKQSLPYLEAANLLLQAQLPPKPPAWAWAEGWTRYGP-EGEAVPVAIPEERALVFDVEVCLAEGTCPTLAVAISPSAWYSWCSQRLVEERYSWTSQLSPADLIPLEVPTGASSPTQRDWQEQLVVGHNVSFDRAHIREQYLIQGSRMRFLDTMSMHMAISGLSSFQRSLWIAAKQGKHKVQPPTKQGQKSQRKARRGP--AISSWD-WLDISSVNSLAEVHRLYVGGPPLE--KEPRELFVKGTMKDIRENFQDLMQYCAQDVWATHEVFQQQLPLFLERCPHPVTLAGMLEMGVSYLPVNQNWERYLAEAQGTYEELQREMKKSLMDLANDACQLLSGER-YKEDPWLWDLEW 490 HSP 3 Score: 56.6102 bits (135), Expect = 2.985e-7 Identity = 22/59 (37.29%), Postives = 36/59 (61.02%), Query Frame = 3
Query: 1494 SFPKWFRVLVSK-NENSNTFNPDLITSQKSIAVKMLKLKWDGLPLHYDKKNKWGVLIPG 1667
P W+R L + ++ + T P L++ Q + K++ L WDG PLHY +++ WG L+PG
Sbjct: 568 GHPGWYRKLCPRLDDPAWTPGPSLLSLQMRVTPKLMALTWDGFPLHYSERHGWGYLVPG 626
BLAST of DNA polymerase subunit gamma vs. Ensembl Human
Match: POLG (DNA polymerase gamma, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9179]) HSP 1 Score: 429.869 bits (1104), Expect = 5.077e-130 Identity = 230/489 (47.03%), Postives = 288/489 (58.90%), Query Frame = 3
Query: 2118 IPFVWFLPLPHEKGEGNTVGSPFSKSFLNYMQSGRLTSHAANNLLEIMIEGKKSGVFWRNYQNRVQSQFMV---RTS------------KENNESAIIPQVIVAGTVTRRSVERLWLTATNSTNDRVGSELKAMVQTPTNWVMVGADVDSQEQWIAAVLGDS-VTGIHGGTPFGWMVLQGSKVDGTDLHSKTSKMIGISRNAAKVLNYSRMYGAGIKSSTDTLLKYNPELKPQEAFNKIKDLMKQTKG---------------------KRSQGKWVD------------------------------GIESEVFSKLEEIAKSDEPSTPVLNARLSQALEKRVVNEKFMTSKCNWVVQSSGVDYLHCLLTFTKHLIQLYNVNARLCICIHDEIRYLCEEKDKYRLALILQIANLYTRSVFSMKLNLFDLPQSIAFFSEIDIDYCLRKSPTDDCITPSNQNGLLNNYNIQKGESLNIYQILDKTGGRLD 3383
IP WF LPH+ G VGSPF+K FL M+ G L + +E K FWRN R+ SQ +V R++ +E AI+PQV+ AGT+TRR+VE WLTA+N+ DRVGSELKAMVQ P + +VGADVDSQE WIAAVLGD+ G+HG T FGWM LQG K GTDLHSKT+ +GISR AK+ NY R+YGAG + L+++N L QEA K + + TKG R++G W+ G ESE+F+KLE IA SD P TPVL +S+ALE V E+FMTS+ NWVVQSS VDYLH +L K L + + ++ R CI IHDE+RYL E+D+YR AL LQI NL TR +F+ KL L DLPQS+AFFS +DID CLRK T DC TPSN G+ Y I +GE+L+IYQI++ T G L+
Sbjct: 744 IPGCWFFKLPHKDGNSCNVGSPFAKDFLPKMEDGTLQAGPGGASGPRALEINKMISFWRNAHKRISSQMVVWLPRSALPRAVIRHPDYDEEGLYGAILPQVVTAGTITRRAVEPTWLTASNARPDRVGSELKAMVQAPPGYTLVGADVDSQELWIAAVLGDAHFAGMHGCTAFGWMTLQGRKSRGTDLHSKTATTVGISREHAKIFNYGRIYGAGQPFAERLLMQFNHRLTQQEAAEKAQQMYAATKGLRWYRLSDEGEWLVRELNLPVDRTEGGWISLQDLRKVQRETARKSQWKKWEVVAERAWKGGTESEMFNKLESIATSDIPRTPVLGCCISRALEPSAVQEEFMTSRVNWVVQSSAVDYLHLMLVAMKWLFEEFAIDGRFCISIHDEVRYLVREEDRYRAALALQITNLLTRCMFAYKLGLNDLPQSVAFFSAVDIDRCLRKEVTMDCKTPSNPTGMERRYGIPQGEALDIYQIIELTKGSLE 1232 HSP 2 Score: 275.404 bits (703), Expect = 1.443e-75 Identity = 160/435 (36.78%), Postives = 232/435 (53.33%), Query Frame = 3
Query: 204 NSSDDKLRINMMNIQMINKKFQETIFGSKS--TAELDFFEINSLFKNFKIDTEKTTLNKNVDFDLPPLLGENIEIHLQKAAETLNDPYMALLKGLDDWKIPQMPTMWSFQEGWTKYDTINNKFYKVSVPEENLLIFDVETLPKYTQRAVMAVAVGKSYWYSWTSKYLLDGICKDDSEICKDDLIPLYSNDDKSKP-------KCIVGHFVSFDRARIRDEYCIKGTGTRFIDTMSMQIAIRGMTSLQRSLKISFNNNNTENRIWKLYFSNSSKNGMNNSPEDIEESDKWLTEASLNSLVDVYQYYFPNCNLSSLKDKRETFIKGTIDDIVNDFQALMTYCATDVIMTAKIFQKLWTDYRVRFPHPASFTGMLEMGSLYLPVNSNLNTYINRASTTYESMIKKEKEILMELAQKS--LASKEKEYINDPWLWDLDW 1475
+S +LR N ++IQM+++ E IFG E + + + +V+ LPPL G+N++ H + A+ + PY+ L ++P P W++ EGWT+Y + V++PEE L+FDVE +AVA+ S WYSW S+ L++ S++ DLIPL S P + +VGH VSFDRA IR++Y I+G+ RF+DTMSM +AI G++S QRSL I+ + + S + I D WL +S+NSL +V++ Y L K+ RE F+KGT+ DI +FQ LM YCA DV T ++FQ+ + R PHP + GMLEMG YLPVN N Y+ A TYE + ++ K+ LM+LA + L S E+ Y DPWLWDL+W
Sbjct: 63 SSEGGQLRHNPLDIQMLSRGLHEQIFGQGGEMPGEAAVRRSVEHLQKHGLWGQPAVPLPDVELRLPPLYGDNLDQHFRLLAQKQSLPYLEAANLLLQAQLPPKPPAWAWAEGWTRYGP-EGEAVPVAIPEERALVFDVEVCLAEGTCPTLAVAISPSAWYSWCSQRLVEERYSWTSQLSPADLIPLEVPTGASSPTQRDWQEQLVVGHNVSFDRAHIREQYLIQGSRMRFLDTMSMHMAISGLSSFQRSLWIAAKQGKHKVQPPTKQGQKSQRKARRGP--AISSWD-WLDISSVNSLAEVHRLYVGGPPLE--KEPRELFVKGTMKDIRENFQDLMQYCAQDVWATHEVFQQQLPLFLERCPHPVTLAGMLEMGVSYLPVNQNWERYLAEAQGTYEELQREMKKSLMDLANDACQLLSGER-YKEDPWLWDLEW 490 HSP 3 Score: 56.6102 bits (135), Expect = 2.985e-7 Identity = 22/59 (37.29%), Postives = 36/59 (61.02%), Query Frame = 3
Query: 1494 SFPKWFRVLVSK-NENSNTFNPDLITSQKSIAVKMLKLKWDGLPLHYDKKNKWGVLIPG 1667
P W+R L + ++ + T P L++ Q + K++ L WDG PLHY +++ WG L+PG
Sbjct: 568 GHPGWYRKLCPRLDDPAWTPGPSLLSLQMRVTPKLMALTWDGFPLHYSERHGWGYLVPG 626
BLAST of DNA polymerase subunit gamma vs. Ensembl Human
Match: POLG (DNA polymerase gamma, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9179]) HSP 1 Score: 389.037 bits (998), Expect = 5.517e-118 Identity = 217/489 (44.38%), Postives = 272/489 (55.62%), Query Frame = 3
Query: 2118 IPFVWFLPLPHEKGEGNTVGSPFSKSFLNYMQSGRLTSHAANNLLEIMIEGKKSGVFWRNYQNRVQSQFMV---RTS------------KENNESAIIPQVIVAGTVTRRSVERLWLTATNSTNDRVGSELKAMVQTPTNWVMVGADVDSQEQWIAAVLGDS-VTGIHGGTPFGWMVLQGSKVDGTDLHSKTSKMIGISRNAAKVLNYSRMYGAGIKSSTDTLLKYNPELKPQEAFNKIKDLMKQTKG---------------------KRSQGKWVD------------------------------GIESEVFSKLEEIAKSDEPSTPVLNARLSQALEKRVVNEKFMTSKCNWVVQSSGVDYLHCLLTFTKHLIQLYNVNARLCICIHDEIRYLCEEKDKYRLALILQIANLYTRSVFSMKLNLFDLPQSIAFFSEIDIDYCLRKSPTDDCITPSNQNGLLNNYNIQKGESLNIYQILDKTGGRLD 3383
IP WF LPH+ G VGSPF+K FL M+ G L + +E K FWRN R+ SQ +V R++ +E AI+PQV+ AGT+TRR+VE WLTA+N+ DRVGSELKAMVQ P + +VGADVDSQE WIAAVLGD+ G+HG T FGWM LQG K GTDLHSKT+ +GISR AK+ NY R+YGAG + L+++N L QEA K + + TKG R++G W+ G ESE+F+KLE IA SD P TPVL +S+ALE V E+FMTS+ NWVVQSS VDYLH +L K L + + ++ R CI IHDE+RYL E+D+YR AL LQI NL T S +DID CLRK T DC TPSN G+ Y I +GE+L+IYQI++ T G L+
Sbjct: 435 IPGCWFFKLPHKDGNSCNVGSPFAKDFLPKMEDGTLQAGPGGASGPRALEINKMISFWRNAHKRISSQMVVWLPRSALPRAVIRHPDYDEEGLYGAILPQVVTAGTITRRAVEPTWLTASNARPDRVGSELKAMVQAPPGYTLVGADVDSQELWIAAVLGDAHFAGMHGCTAFGWMTLQGRKSRGTDLHSKTATTVGISREHAKIFNYGRIYGAGQPFAERLLMQFNHRLTQQEAAEKAQQMYAATKGLRWYRLSDEGEWLVRELNLPVDRTEGGWISLQDLRKVQRETARKSQWKKWEVVAERAWKGGTESEMFNKLESIATSDIPRTPVLGCCISRALEPSAVQEEFMTSRVNWVVQSSAVDYLHLMLVAMKWLFEEFAIDGRFCISIHDEVRYLVREEDRYRAALALQITNLLT--------------------SAVDIDRCLRKEVTMDCKTPSNPTGMERRYGIPQGEALDIYQIIELTKGSLE 903 HSP 2 Score: 130.568 bits (327), Expect = 5.527e-30 Identity = 68/147 (46.26%), Postives = 91/147 (61.90%), Query Frame = 3
Query: 1041 WLTEASLNSLVDVYQYYFPNCNLSSLKDKRETFIKGTIDDIVNDFQALMTYCATDVIMTAKIFQKLWTDYRVRFPHPASFTGMLEMGSLYLPVNSNLNTYINRASTTYESMIKKEKEILMELAQKS--LASKEKEYINDPWLWDLDW 1475
WL +S+NSL +V++ Y L K+ RE F+KGT+ DI +FQ LM YCA DV T ++FQ+ + R PHP + GMLEMG YLPVN N Y+ A TYE + ++ K+ LM+LA + L S E+ Y DPWLWDL+W
Sbjct: 38 WLDISSVNSLAEVHRLYVGGPPLE--KEPRELFVKGTMKDIRENFQDLMQYCAQDVWATHEVFQQQLPLFLERCPHPVTLAGMLEMGVSYLPVNQNWERYLAEAQGTYEELQREMKKSLMDLANDACQLLSGER-YKEDPWLWDLEW 181 HSP 3 Score: 56.225 bits (134), Expect = 4.233e-7 Identity = 22/59 (37.29%), Postives = 36/59 (61.02%), Query Frame = 3
Query: 1494 SFPKWFRVLVSK-NENSNTFNPDLITSQKSIAVKMLKLKWDGLPLHYDKKNKWGVLIPG 1667
P W+R L + ++ + T P L++ Q + K++ L WDG PLHY +++ WG L+PG
Sbjct: 259 GHPGWYRKLCPRLDDPAWTPGPSLLSLQMRVTPKLMALTWDGFPLHYSERHGWGYLVPG 317
BLAST of DNA polymerase subunit gamma vs. Ensembl Human
Match: POLG (DNA polymerase gamma, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9179]) HSP 1 Score: 345.125 bits (884), Expect = 9.149e-101 Identity = 190/422 (45.02%), Postives = 238/422 (56.40%), Query Frame = 3
Query: 2118 IPFVWFLPLPHEKGEGNTVGSPFSKSFLNYMQSGRLTSHAANNLLEIMIEGKKSGVFWRNYQNRVQSQFMV---RTS------------KENNESAIIPQVIVAGTVTRRSVERLWLTATNSTNDRVGSELKAMVQTPTNWVMVGADVDSQEQWIAAVLGDS-VTGIHGGTPFGWMVLQGSKVDGTDLHSKTSKMIGISRNAAKVLNYSRMYGAGIKSSTDTLLKYNPELKPQEAFNKIKDLMKQTKG---------------------KRSQGKWVD------------------------------GIESEVFSKLEEIAKSDEPSTPVLNARLSQALEKRVVNEKFMTSKCNWVVQSSGVDYLHCLLTFTKHLIQLYNVNARLCICIHDEIRYLCEEKDKYRLALILQIANLYTRSVFS 3182
IP WF LPH+ G VGSPF+K FL M+ G L + +E K FWRN R+ SQ +V R++ +E AI+PQV+ AGT+TRR+VE WLTA+N+ DRVGSELKAMVQ P + +VGADVDSQE WIAAVLGD+ G+HG T FGWM LQG K GTDLHSKT+ +GISR AK+ NY R+YGAG + L+++N L QEA K + + TKG R++G W+ G ESE+F+KLE IA SD P TPVL +S+ALE V E+FMTS+ NWVVQSS VDYLH +L K L + + ++ R CI IHDE+RYL E+D+YR AL LQI NL T + S
Sbjct: 611 IPGCWFFKLPHKDGNSCNVGSPFAKDFLPKMEDGTLQAGPGGASGPRALEINKMISFWRNAHKRISSQMVVWLPRSALPRAVIRHPDYDEEGLYGAILPQVVTAGTITRRAVEPTWLTASNARPDRVGSELKAMVQAPPGYTLVGADVDSQELWIAAVLGDAHFAGMHGCTAFGWMTLQGRKSRGTDLHSKTATTVGISREHAKIFNYGRIYGAGQPFAERLLMQFNHRLTQQEAAEKAQQMYAATKGLRWYRLSDEGEWLVRELNLPVDRTEGGWISLQDLRKVQRETARKSQWKKWEVVAERAWKGGTESEMFNKLESIATSDIPRTPVLGCCISRALEPSAVQEEFMTSRVNWVVQSSAVDYLHLMLVAMKWLFEEFAIDGRFCISIHDEVRYLVREEDRYRAALALQITNLLTSKIPS 1032 HSP 2 Score: 246.514 bits (628), Expect = 1.025e-66 Identity = 142/364 (39.01%), Postives = 201/364 (55.22%), Query Frame = 3
Query: 411 NIEIHLQKAAETLNDPYMALLKGLDDWKIPQMPTMWSFQEGWTKYDTINNKFYKVSVPEENLLIFDVETLPKYTQRAVMAVAVGKSYWYSWTSKYLLDGICKDDSEICKDDLIPLYSNDDKSKP-------KCIVGHFVSFDRARIRDEYCIKGTGTRFIDTMSMQIAIRGMTSLQRSLKISFNNNNTENRIWKLYFSNSSKNGMNNSPEDIEESDKWLTEASLNSLVDVYQYYFPNCNLSSLKDKRETFIKGTIDDIVNDFQALMTYCATDVIMTAKIFQKLWTDYRVRFPHPASFTGMLEMGSLYLPVNSNLNTYINRASTTYESMIKKEKEILMELAQKS--LASKEKEYINDPWLWDLDW 1475
N++ H + A+ + PY+ L ++P P W++ EGWT+Y + V++PEE L+FDVE +AVA+ S WYSW S+ L++ S++ DLIPL S P + +VGH VSFDRA IR++Y I+G+ RF+DTMSM +AI G++S QRSL I+ + + S + I D WL +S+NSL +V++ Y L K+ RE F+KGT+ DI +FQ LM YCA DV T ++FQ+ + R PHP + GMLEMG YLPVN N Y+ A TYE + ++ K+ LM+LA + L S E+ Y DPWLWDL+W
Sbjct: 1 NLDQHFRLLAQKQSLPYLEAANLLLQAQLPPKPPAWAWAEGWTRYGP-EGEAVPVAIPEERALVFDVEVCLAEGTCPTLAVAISPSAWYSWCSQRLVEERYSWTSQLSPADLIPLEVPTGASSPTQRDWQEQLVVGHNVSFDRAHIREQYLIQGSRMRFLDTMSMHMAISGLSSFQRSLWIAAKQGKHKVQPPTKQGQKSQRKARRGP--AISSWD-WLDISSVNSLAEVHRLYVGGPPLE--KEPRELFVKGTMKDIRENFQDLMQYCAQDVWATHEVFQQQLPLFLERCPHPVTLAGMLEMGVSYLPVNQNWERYLAEAQGTYEELQREMKKSLMDLANDACQLLSGER-YKEDPWLWDLEW 357 HSP 3 Score: 56.6102 bits (135), Expect = 3.054e-7 Identity = 22/59 (37.29%), Postives = 36/59 (61.02%), Query Frame = 3
Query: 1494 SFPKWFRVLVSK-NENSNTFNPDLITSQKSIAVKMLKLKWDGLPLHYDKKNKWGVLIPG 1667
P W+R L + ++ + T P L++ Q + K++ L WDG PLHY +++ WG L+PG
Sbjct: 435 GHPGWYRKLCPRLDDPAWTPGPSLLSLQMRVTPKLMALTWDGFPLHYSERHGWGYLVPG 493
BLAST of DNA polymerase subunit gamma vs. Ensembl Human
Match: POLG (DNA polymerase gamma, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9179]) HSP 1 Score: 276.559 bits (706), Expect = 5.332e-77 Identity = 160/435 (36.78%), Postives = 232/435 (53.33%), Query Frame = 3
Query: 204 NSSDDKLRINMMNIQMINKKFQETIFGSKS--TAELDFFEINSLFKNFKIDTEKTTLNKNVDFDLPPLLGENIEIHLQKAAETLNDPYMALLKGLDDWKIPQMPTMWSFQEGWTKYDTINNKFYKVSVPEENLLIFDVETLPKYTQRAVMAVAVGKSYWYSWTSKYLLDGICKDDSEICKDDLIPLYSNDDKSKP-------KCIVGHFVSFDRARIRDEYCIKGTGTRFIDTMSMQIAIRGMTSLQRSLKISFNNNNTENRIWKLYFSNSSKNGMNNSPEDIEESDKWLTEASLNSLVDVYQYYFPNCNLSSLKDKRETFIKGTIDDIVNDFQALMTYCATDVIMTAKIFQKLWTDYRVRFPHPASFTGMLEMGSLYLPVNSNLNTYINRASTTYESMIKKEKEILMELAQKS--LASKEKEYINDPWLWDLDW 1475
+S +LR N ++IQM+++ E IFG E + + + +V+ LPPL G+N++ H + A+ + PY+ L ++P P W++ EGWT+Y + V++PEE L+FDVE +AVA+ S WYSW S+ L++ S++ DLIPL S P + +VGH VSFDRA IR++Y I+G+ RF+DTMSM +AI G++S QRSL I+ + + S + I D WL +S+NSL +V++ Y L K+ RE F+KGT+ DI +FQ LM YCA DV T ++FQ+ + R PHP + GMLEMG YLPVN N Y+ A TYE + ++ K+ LM+LA + L S E+ Y DPWLWDL+W
Sbjct: 63 SSEGGQLRHNPLDIQMLSRGLHEQIFGQGGEMPGEAAVRRSVEHLQKHGLWGQPAVPLPDVELRLPPLYGDNLDQHFRLLAQKQSLPYLEAANLLLQAQLPPKPPAWAWAEGWTRYGP-EGEAVPVAIPEERALVFDVEVCLAEGTCPTLAVAISPSAWYSWCSQRLVEERYSWTSQLSPADLIPLEVPTGASSPTQRDWQEQLVVGHNVSFDRAHIREQYLIQGSRMRFLDTMSMHMAISGLSSFQRSLWIAAKQGKHKVQPPTKQGQKSQRKARRGP--AISSWD-WLDISSVNSLAEVHRLYVGGPPLE--KEPRELFVKGTMKDIRENFQDLMQYCAQDVWATHEVFQQQLPLFLERCPHPVTLAGMLEMGVSYLPVNQNWERYLAEAQGTYEELQREMKKSLMDLANDACQLLSGER-YKEDPWLWDLEW 490 HSP 2 Score: 232.646 bits (592), Expect = 2.526e-62 Identity = 123/250 (49.20%), Postives = 153/250 (61.20%), Query Frame = 3
Query: 2118 IPFVWFLPLPHEKGEGNTVGSPFSKSFLNYMQSGRLTSHAANNLLEIMIEGKKSGVFWRNYQNRVQSQFMV---RTS------------KENNESAIIPQVIVAGTVTRRSVERLWLTATNSTNDRVGSELKAMVQTPTNWVMVGADVDSQEQWIAAVLGDS-VTGIHGGTPFGWMVLQGSKVDGTDLHSKTSKMIGISRNAAKVLNYSRMYGAGIKSSTDTLLKYNPELKPQEAFNKIKDLMKQTKGKR 2819
IP WF LPH+ G VGSPF+K FL M+ G L + +E K FWRN R+ SQ +V R++ +E AI+PQV+ AGT+TRR+VE WLTA+N+ DRVGSELKAMVQ P + +VGADVDSQE WIAAVLGD+ G+HG T FGWM LQG K GTDLHSKT+ +GISR AK+ NY R+YGAG + L+++N L QEA K + + TKG R
Sbjct: 744 IPGCWFFKLPHKDGNSCNVGSPFAKDFLPKMEDGTLQAGPGGASGPRALEINKMISFWRNAHKRISSQMVVWLPRSALPRAVIRHPDYDEEGLYGAILPQVVTAGTITRRAVEPTWLTASNARPDRVGSELKAMVQAPPGYTLVGADVDSQELWIAAVLGDAHFAGMHGCTAFGWMTLQGRKSRGTDLHSKTATTVGISREHAKIFNYGRIYGAGQPFAERLLMQFNHRLTQQEAAEKAQQMYAATKGLR 993 HSP 3 Score: 56.6102 bits (135), Expect = 2.895e-7 Identity = 22/59 (37.29%), Postives = 36/59 (61.02%), Query Frame = 3
Query: 1494 SFPKWFRVLVSK-NENSNTFNPDLITSQKSIAVKMLKLKWDGLPLHYDKKNKWGVLIPG 1667
P W+R L + ++ + T P L++ Q + K++ L WDG PLHY +++ WG L+PG
Sbjct: 568 GHPGWYRKLCPRLDDPAWTPGPSLLSLQMRVTPKLMALTWDGFPLHYSERHGWGYLVPG 626
BLAST of DNA polymerase subunit gamma vs. Ensembl Celegans
Match: polg-1 (POLG (Mitochondrial DNA POLymerase Gamma) [Source:UniProtKB/TrEMBL;Acc:Q9U208]) HSP 1 Score: 201.83 bits (512), Expect = 1.326e-52 Identity = 145/476 (30.46%), Postives = 225/476 (47.27%), Query Frame = 3
Query: 390 LPPLLGENIEIHLQKAAETLNDPYMALLKGLDDWKIPQMPTM---------WSFQEGWTKYD-TINNKFYKVSVPEENLLIFDVETLPKYTQRAVMAVAVGKSYWYSWTSKYLLDGICKDDSEI----CKDDLIPLYSNDDKSKPKCIVGHFVSFDRARIRDEY-CIKGTGTRFIDTMSMQIAIRGMTSLQRSLKISFNNNNTENRIWKLYFSNSSKNGMNNSPEDIEESDKWLTEASLNSLVDVYQYYFP----NCNLSSLKDKRETFIKGTIDDIVNDFQALMTYCATDVIMTAKIFQKLWTDYRVRFPHPASFTGMLEMGSLYLPVNSNLNTYINRASTTYESMIKKEKEILME---LAQKSLASKEKEY---INDPWLWDLDWSTTKKSSFPKWFRVLVSK----NENSNTFNPDLITSQKSIAVKMLKLKWDGLPLHYDKKNKWGVLIPGCYLPV---WYDEKFMDISNKL 1721
LPPL+ +N+ H AE Y LL+ ++ + + W ++ GWT+Y + + + P +++L FD+E + + +A+A+G+ WY W S L+ +SEI K DLIP+ + K I+GH V FDRAR R+ Y I G+ RF+DTMSM I + GM Q+SL ++ + ++S + MN W S NSLV V+ + +P N S K R +F+K I+ I DFQ LM+YCA D I+ A+I+ +LW ++ RFPHPA+ +GML MG++YLP+NS + + T E ++E L K L + +E ND W+W DW+ +K S +WF L N + + + I + + + + PL + WG L+P + PV D F +I K+
Sbjct: 60 LPPLVADNVVDHFGVLAEQQTRKYKELLEKACEFDLETAKNVLEHIDKTDGWHYKTGWTRYPFSTSEPPETIDFPRDSILFFDIELVVRDGTLPTLAIALGRDAWYGWCSDRLIY-----ESEIPEIPTKADLIPI---GEIGMEKVIIGHNVGFDRARCREAYQSINGSKIRFMDTMSMSIPMYGMADHQQSLY----------EMYDVETNDSHSDWMN----------AWKGRVSKNSLVAVHDHLYPDKAINAEGFSKKTMRASFVKDPIEQIREDFQPLMSYCARDNILCAEIYFRLWPEFIKRFPHPATLSGMLNMGNVYLPINSYWKMFYEKNVQTCEQKKTAATRKIIESARLVAKRLDDEGEEIGPEKNDVWMWHHDWTFNQKQSNFEWFNKLFKARSFVNLSLDEVDSHHIALKSHLIPAIFGFVFGPFPLFKTRSKGWGFLVPN-WKPVEKALQDPNFHEIDAKI 506 HSP 2 Score: 166.392 bits (420), Expect = 1.974e-41 Identity = 108/296 (36.49%), Postives = 155/296 (52.36%), Query Frame = 3
Query: 2040 SLYNFQMNDFSSLFAKTKCLLTENPIIP-----------FVWFLPLPHEKGEGNTVGSPFSKSFLNYMQSGRLTSHAANNLLEIMIEGKKSGVFWRNYQNRVQSQFMV-------RTSK--ENNESAIIPQVIVAGTVTRRSVERLWLTATN-STNDRVGSELKAMVQTPTNWVMVGADVDSQEQWIAAVLGDSVT--------GIHGGTPFGWMVLQGSKVDGTDLHSKTSKMIGISRNAAKVLNYSRMYGAGIKSSTDTLLKYNPELKPQEAFNKIKDLMKQTKGKRSQGKWVD 2840
++ F + F +L E PI P V F L H GEGN VG P +K F ++ L +++++ ++ FW +Y +R S+ + RT++ E + AI V+ AGT++RRSV +LW+T TN ST +G+ +KAMVQ P + +VGADVDSQEQW+AA+ GD+ + G T F M+L GSK D TDLHS + + ISRN AKVLNY+R+YG+G + L++ LK EA + L K TKG ++ VD
Sbjct: 513 AVKKFPLRSFYETVQNNVYMLGELPISPDRKGFELDEAGLVRFYQLDHPSGEGN-VGDPLTKHFAKDLKELVLRPTRYEEYFDVVLDSIQTTQFWTSYSDRYCSEVAIWSPEATWRTAENLEMIDGAIAAAVVPAGTISRRSVHKLWVTLTNQSTGHVIGTGIKAMVQAPAGYRLVGADVDSQEQWLAALYGDASAEKRLPLEKRVAGKTAFSNMMLAGSKSDNTDLHSVVASQLKISRNHAKVLNYARLYGSGETHAGKHLMRVG-GLKQSEAESTASQLFKLTKGDVAKYMKVD 806 HSP 3 Score: 134.42 bits (337), Expect = 1.474e-31 Identity = 72/192 (37.50%), Postives = 107/192 (55.73%), Query Frame = 3
Query: 2832 WVDGIESEVFSKLEEIAKSDEPSTPVLNARLSQALEK--------RVVNEKFMTSKCNWVVQSSGVDYLHCLLTFTKHLIQLYNVNARLCICIHDEIRYLCEEKDKYRLALILQIANLYTRSVFSMKLNLFDLPQSIAFFSEIDIDYCLRKSPTDDCITPSNQNGLLNNYNIQKGESLNIYQILDKTGGRLD 3383
+V G ES F+ LE A + + TP+L +++ +L K + K+ S NW+VQSS VD+LH LL + L Y ++AR I IHDE+RY+C+E D RLAL LQ++NL R+ S ++ + LP ++AFFS++D D LRK + I P + I G + + +L TGG+LD
Sbjct: 888 FVGGYESSTFNFLETSAAAHDLRTPILGCQIADSLGKLPEGTPDSAYFDRKYKRSVMNWIVQSSAVDFLHLLLVSMQWLCDTYKIDARFVISIHDEVRYMCKEPDAPRLALALQLSNLLVRAYISQRVGICQLPNTVAFFSQVDCDTVLRKEVDTESINP-------DGSKIADGVAWTVDDLLKLTGGKLD 1072
BLAST of DNA polymerase subunit gamma vs. Ensembl Fly
Match: tam (gene:FBgn0004406 transcript:FBtr0080571) HSP 1 Score: 350.517 bits (898), Expect = 2.415e-102 Identity = 194/475 (40.84%), Postives = 269/475 (56.63%), Query Frame = 3
Query: 2127 VWFLPLPHEKGEGNTVGSPFSKSFLN-----YMQSGRLTSHAANNLLEIMIEGKKSGVFWRNYQNRVQSQFMVRTSKEN--NE-----------SAIIPQVIVAGTVTRRSVERLWLTATNSTNDRVGSELKAMVQTPTNWVMVGADVDSQEQWIAAVLGDS-VTGIHGGTPFGWMVLQGSKVDGTDLHSKTSKMIGISRNAAKVLNYSRMYGAGIKSSTDTLLKYNPELKPQEAFNKIKDLMKQTKGKR-------------------------------------SQGKWVDGIESEVFSKLEEIAKSDEPSTPVLNARLSQALEKRVVNE---KFMTSKCNWVVQSSGVDYLHCLLTFTKHLIQLYNVNARLCICIHDEIRYLCEEKDKYRLALILQIANLYTRSVFSMKLNLFDLPQSIAFFSEIDIDYCLRKSPTDDCITPSNQNGLLNNYNIQKGESLNIYQILDKTGG 3374
+FL LPH+ G VG+P SK FLN + SG + AA +++I + +WRN ++R+ Q +V + NE AI PQV+ GT+TRR++E W+TA+NS DR+GSEL++MVQ P + +VGADVDSQE WIA+VLGD+ G HG TP GWM L GSK +G+D+HS T+K +GISR+ AKV+NY+R+YGAG + L ++NP EA K + TKGKR + W G ES +F++LEEIA +P TP L RLS+ALE E +F+ ++ NWVVQS VD+LH +L + L+ + R C+ HDE+RYL +E+ + AL + I NL TRS ++ L DLP S+AFFS +++D LRK T DC TPSN +GL Y IQ G+SL++ + ++K GG
Sbjct: 666 CFFLKLPHKNGPSFRVGNPLSKDFLNKFAENVLSSGDPSCQAAARVIDIA----RMMSYWRNNRDRIMGQMVVWLDSQQLPNEFTGEKCQPIAYGAICPQVVACGTLTRRAMEPTWMTASNSRPDRLGSELRSMVQAPPGYRLVGADVDSQELWIASVLGDAYACGEHGATPLGWMTLSGSKSNGSDMHSITAKAVGISRDHAKVINYARIYGAGQLFAETLLRQFNPTFSASEAKAKAMKMFSITKGKRVYRLREEFHDELEDRAYSSYEASRLAIQRNRTLAEVFHRPNWQGGTESAMFNRLEEIATGSQPRTPFLGGRLSRALEADTGPEQEQRFLPTRINWVVQSGAVDFLHLMLVSMRWLM---GSHVRFCLSFHDELRYLVKEELSPKAALAMHITNLMTRSFCVSRIGLQDLPMSVAFFSSVEVDTVLRKECTMDCKTPSNPHGLRIGYGIQPGQSLSVAEAIEKAGG 1133 HSP 2 Score: 271.166 bits (692), Expect = 7.294e-75 Identity = 178/559 (31.84%), Postives = 259/559 (46.33%), Query Frame = 3
Query: 231 NMMNIQMINKKFQETIF--GSKSTAELDFFEINSL---FKNFKIDTEKTTLNKNVDFDLPPLLGENIEIHLQKAAETLNDPYMALLKGLDDW-KIPQMPTMWSFQEGWTKYDTINNKFYKVSVPEENLLIFDVETLPKYTQRAVMAVAVGKSYWYSWTSKYL---------LDGICKD-DSE---ICKDDLIPLYSNDDKSKPKCIVGHFVSFDRARIRDEYCIKGTGTRFIDTMSMQIAIRGMTSLQRSLKISFNNNNTENRIWKLYFSNSSKNGMNNSPEDIEESDKWLTEASLNSLVDVYQYYFPNCNLSSLKDKRETFIKGTIDDIVNDFQALMTYCATDVIMTAKIFQKLWTDYRVRFPHPASFTGMLEMGSLYLPVNSNLNTYINRASTTYESMIKKEKEILMELAQKSLA-SKEKEYINDPWLWDLDWSTTKKS-------------------------------------------------SFPKWFRVLVSK----------NENSNTFNPDL--ITSQKSIAVKMLKLKWDGLPLHYDKKNKWGVLIP 1664
N++ +QMI++ +F +S +E + +D E + +V LP L G NIE H A+ PY LL L ++P+ P W+F GWT YD + V P E L+FDVE Q V+A AV WYSW S L L+ + D DSE D+LIPL + + P +VGH VS+DRAR++++Y + TGTRF+DTMS+ + + G+TS QR++ + + E E WL ++SLNSLV+V++ Y LS K+ R F++GT++ + FQ+L YCA+DV T +I + L+ Y RFPHPAS GMLEMGS YLPVNSN YI A TYE + + K L A+++ + + +Y + WLWD DWS + +P W+R L K ++ ++P I++ IA K+L L W+G PLHY+++ WG L+P
Sbjct: 54 NLVKVQMISRNLHAQLFPQAPRSISEQQVASAKVYKDELRRHGVDIESSAPVSDVQLKLPALRGANIEEHFHNIAKEQVQPYEELLLPLVQCEQLPKRPKRWAFHTGWTAYDPEDGTATPVDHPLEKGLVFDVEVCVSEGQAPVLATAVSTKRWYSWVSSKLTKHRLSVEKLEPLDVDTDSERPHYTTDELIPLGT----TGPGLVVGHNVSYDRARLKEQYLTEDTGTRFVDTMSLHMCVSGVTSYQRAM-------------------------LKSKKEPAAEDLGWLEQSSLNSLVEVHRLYCGGDTLS--KEPRNIFVEGTLEQVRQSFQSLTNYCASDVEATHRILRVLYPLYAERFPHPASLAGMLEMGSAYLPVNSNWERYIREAQLTYEDLSIEAKYHLGRRAEEACSLLLDDQYRQNLWLWDEDWSVQELKLKQPPKRKPLPTVELKDSGNTPEERRLQAKFQHLYDQQALLPARRPLLPGYPLWYRKLCRKPPAKRADEILEDDEEPWSPGASEISTGMQIAPKLLSLCWEGYPLHYEREQGWGFLVP 581
BLAST of DNA polymerase subunit gamma vs. Ensembl Zebrafish
Match: polg (polymerase (DNA directed), gamma [Source:ZFIN;Acc:ZDB-GENE-060303-1]) HSP 1 Score: 469.159 bits (1206), Expect = 4.359e-145 Identity = 275/701 (39.23%), Postives = 371/701 (52.92%), Query Frame = 3
Query: 1494 SFPKWFRVLVSKNENSNTFNP--DLITSQKSIAVKMLKLKWDGLPLHYDKKNKWGVLIPGCYLPVWYDEKFMDISNKLIWPIIPVERISPSYIDYFQFPLQKYVQFWVPLFVSRLEAFRDFLLSLGNSDLTKYNVFVEYMMAIVEPINFTPENLTKVNSLLCEIKEITLRNSKGYYNSNEEGPLSLYNFQMNDFSSLFAKTKCLLTENPIIPFVWFLPLPHEKGEGNTVGSPFSKSFLNYMQSGRLTSHAANNLLEIMIEGKKSGVFWRNYQNRVQSQFMVRTSK---------------ENNESAIIPQVIVAGTVTRRSVERLWLTATNSTNDRVGSELKAMVQTPTNWVMVGADVDSQEQWIAAVLGDS-VTGIHGGTPFGWMVLQGSKVDGTDLHSKTSKMIGISRNAAKVLNYSRMYGAGIKSSTDTLLKYNPELKPQEAFNKIKDLMKQTKGKR-----SQGKWV-------------------------------------------------DGIESEVFSKLEEIAKSDEPSTPVLNARLSQALEKRVVNEKFMTSKCNWVVQSSGVDYLHCLLTFTKHLIQLYNVNARLCICIHDEIRYLCEEKDKYRLALILQIANLYTRSVFSMKLNLFDLPQSIAFFSEIDIDYCLRKSPTDDCITPSNQNGLLNNYNIQKGESLNIYQILDKTGGRL 3380
+ P W+R L K + ++P LI+ Q I K++ L WDG PLHY ++ WG L+PG +DIS P+ P I Y +Y + ++ ++ VS D + ++++ +F + ++ P K IT + + + + N E P N ND + IP WF LPH+ G N VGSPFSK FL+ M+SG L + +E K FWRN Q R+ SQ +V + E AI+PQVI AGTVTRR+VE WLTA+N+ DRVGSELKAMVQ P + +VGADVDSQE WIAA+LG++ G+HG T FGWM LQG K GTDLHS+T+ +GISR AKV NY R+YGAG + L+++N L QEA K + + TKG R +G+W+ DG ES +F+KLE IA+SD P+TPVLN R+S+ALE V E+F+TS+ NWVVQSS VDYLH +L + L + ++++ R CI IHDE+RYL +D+YR AL LQI NL TR +F+ KL + DLPQS+AFFS +DID CLRK T DC TPS+ G+ Y + +GE+L+IYQI++ T G L
Sbjct: 535 AHPSWYRKLCVKMSEAEDWSPGASLISLQMRITPKLMGLTWDGFPLHYTDQHGWGYLVPG-------RRDNLDISEDNEEPVCPYRAIESVYKEYCEQKGKEQPKY-PDSPVSDELMLTDTAVWQTVEEVSRLEMFDDEALSTAAPS-----------------KRITKKVNSVFKSLNGECPYHHGNGPYNDVN---------------IPGCWFFKLPHKDGNENNVGSPFSKDFLSKMESGTLQAGREGTNATRALEINKMISFWRNAQKRISSQMVVWLRRAELPRSVRLHQDYDEEGQYGAILPQVIPAGTVTRRAVEPTWLTASNARKDRVGSELKAMVQVPPAYHLVGADVDSQELWIAAMLGEAHFAGMHGCTAFGWMTLQGKKSQGTDLHSRTADAVGISREHAKVFNYGRIYGAGQPFAERLLMQFNHRLSQQEAAGKARQMYALTKGLRRYHLSEEGEWLLQKLNVNVERAEDGSISLQDLRKISKVATQSTTRGSKKKWNLTAGRVWTDGTESYMFNKLESIAQSDRPATPVLNCRISRALEPSAVQEEFITSRVNWVVQSSAVDYLHLMLVSMRWLFEEHDIDGRFCISIHDEVRYLVTSEDRYRAALALQITNLLTRCMFAFKLGMMDLPQSVAFFSAVDIDKCLRKEVTMDCKTPSSPAGVERRYGLPQGEALDIYQIIEITKGSL 1195 HSP 2 Score: 276.944 bits (707), Expect = 1.766e-76 Identity = 156/431 (36.19%), Postives = 242/431 (56.15%), Query Frame = 3
Query: 216 DKLRINMMNIQMINKKFQETIFGSKSTAELDFFEINSL--FKNFKIDTEKTTLNKNVDFDLPPLLGENIEIHLQKAAETLNDPYMALLKGLDDWKIPQMPTMWSFQEGWTKYDTINNKFYKVSVPEENLLIFDVETLPKYTQRAVMAVAVGKSYWYSWTSKYLLDGICKDDSEICKDDLIPLYSNDDKSKPK-------CIVGHFVSFDRARIRDEYCIKGTGTRFIDTMSMQIAIRGMTSLQRSLKISFNNNNTENRIWKLYFSNSSKNGMNNSPEDIE-ESDKWLTEASLNSLVDVYQYYFPNCNLSSLKDKRETFIKGTIDDIVNDFQALMTYCATDVIMTAKIFQKLWTDYRVRFPHPASFTGMLEMGSLYLPVNSNLNTYINRASTTYESMIKKEKEILMELAQKSLA-SKEKEYINDPWLWDLDW 1475
D+ R+N +NIQM+++ QE IF ++ D S+ ++ + ++T+L +V LP + G NI+ H + A+ + PY+ L +IP+MP W+++ GWT+Y + + KV+ P+EN L+FDVE +AVA+ + WYSW S L++ S++ DLIPL + + S+P+ +VGH VSFDRA I+++Y +KG+ RF+DTMS+ +AI G+T QRSL ++ + L + PE + S +W+ +S+N+L DV+ Y L +K+ RE F+KG++ DI +FQ LM YCA DV+ T ++F + + R PHP + GMLEMG YLPVN N Y+ A TYE + ++ K+ LM LA + ++ Y +DPWLWDLDW
Sbjct: 36 DQTRLNPLNIQMLSRNLQEQIFRGQTQEYTDEDVERSIRHLEHHGLWGKETSLLPDVQLRLPEMYGSNIDEHFRLLAQKQSLPYLEAASQLQKAQIPEMPQEWAWEVGWTRYGA-DGESQKVNFPDENALVFDVEVCMAEGHCPTLAVALSPTAWYSWCSHRLVEDRYAWSSDLSLADLIPLETLANSSQPRGGEWKERLVVGHNVSFDRAHIKEQYLLKGSKMRFLDTMSLHMAISGLTGFQRSLWMASKYGKRKG----LQEVKEHMKRLGRRPEGPKIGSWEWVNISSINNLADVHALYVGGDPL--MKESRELFVKGSMSDIRGNFQELMQYCALDVLATQEVFTQQLPLFMERCPHPVTLAGMLEMGVCYLPVNHNWRRYLEDAQATYEELQREMKKSLMILADDACQLLQDDRYKDDPWLWDLDW 459
BLAST of DNA polymerase subunit gamma vs. Ensembl Xenopus
Match: tpst1 (tyrosylprotein sulfotransferase 1 [Source:Xenbase;Acc:XB-GENE-953306]) HSP 1 Score: 418.313 bits (1074), Expect = 1.341e-126 Identity = 222/482 (46.06%), Postives = 280/482 (58.09%), Query Frame = 3
Query: 2127 VWFLPLPHEKGEGNTVGSPFSKSFLNYMQSGRLTSHAANNLLEIMIEGKKSGVFWRNYQNRVQSQFMVRTSK---------------ENNESAIIPQVIVAGTVTRRSVERLWLTATNSTNDRVGSELKAMVQTPTNWVMVGADVDSQEQWIAAVLGDS-VTGIHGGTPFGWMVLQGSKVDGTDLHSKTSKMIGISRNAAKVLNYSRMYGAGIKSSTDTLLKYNPELKPQEAFNKIKDLMKQTKGKR------------------------------------------------SQGKWVDGIESEVFSKLEEIAKSDEPSTPVLNARLSQALEKRVVNEKFMTSKCNWVVQSSGVDYLHCLLTFTKHLIQLYNVNARLCICIHDEIRYLCEEKDKYRLALILQIANLYTRSVFSMKLNLFDLPQSIAFFSEIDIDYCLRKSPTDDCITPSNQNGLLNNYNIQKGESLNIYQILDKTGGRL 3380
WF LPH+ G N VGSPF+K FL M+ G L + ++ +E K FWRN R+ SQ +V K EN I+P V+ AGT+TRR+VE WLTA+N+ DRVGSELKAMVQ P + ++GADVDSQE WIAA+LG++ GIHG T FGWM LQG K GTDLHSKT+ +GISR AKV NY R+YGAG + L+++N L ++A K K + TKG R S+ W G ES++F+KLE IA S P TPVL +S+ALE V +F+TS+ NWVVQSS VDYLH +L K L + Y+++ R CI IHDE+RYL + KD+YR AL LQI NL TR +F+ +L + DLPQS+AFFS +DID CLRK T DC TPSN G+ Y I +GE+L+IYQIL T G L
Sbjct: 670 CWFYKLPHKDGYANNVGSPFAKDFLPKMEDGTLQASIGDSSATRALEINKMISFWRNAHKRISSQMVVWMKKGELPRTITRDPEYDEENKYGCILPLVVSAGTITRRAVEPTWLTASNARADRVGSELKAMVQVPPGYHIIGADVDSQELWIAAILGEAHFAGIHGCTAFGWMTLQGKKSTGTDLHSKTASTVGISREHAKVFNYGRIYGAGQAFAERLLMQFNHRLTQEQAAEKAKQMYAVTKGIRRYILSKEGEWLVEELGIPVERGEENSVSLQDLRKIQKEASAKRKWNLVSRRIWTGGTESQMFNKLETIAMSPSPKTPVLGCHISRALEPAAVKGEFITSRINWVVQSSAVDYLHLMLVAMKWLFEAYDIDGRFCISIHDEVRYLVQSKDRYRAALALQITNLLTRCMFASRLGMQDLPQSVAFFSAVDIDKCLRKEVTMDCATPSNPTGMEKRYGIPQGEALDIYQILKVTKGVL 1151 HSP 2 Score: 295.819 bits (756), Expect = 6.510e-83 Identity = 183/550 (33.27%), Postives = 273/550 (49.64%), Query Frame = 3
Query: 213 DDKLRINMMNIQMINKKFQETIFGSKST--AELDFFEINSLFKNFKIDTEKTTLNKNVDFDLPPLLGENIEIHLQKAAETLNDPYMALLKGLDDWKIPQMPTMWSFQEGWTKYDTINNKFYKVSVPEENLLIFDVETLPKYTQRAVMAVAVGKSYWYSWTSKYLLDGICKDDSEICKDDLIPLYSN-------DDKSKPKCIVGHFVSFDRARIRDEYCIKGTGTRFIDTMSMQIAIRGMTSLQRSLKISFNNNNTENRIWKLYFSNSSKNGMNNSPEDIEESDKWLTEASLNSLVDVYQYYFPNCNLSSLKDKRETFIKGTIDDIVNDFQALMTYCATDVIMTAKIFQKLWTDYRVRFPHPASFTGMLEMGSLYLPVNSNLNTYINRASTTYESMIKKEKEILMELAQKSLAS-KEKEYINDPWL----WDL-----------------------------------DWS---------------TTKKSSFPKWFRVLVSKNENSNTF-NPDLITSQKSIAVKMLKLKWDGLPLHYDKKNKWGVLIPG 1667
D R+N +NIQM++K +F K AE D + K+ ++ ++T+ +++ LP L G +IE H Q A+ + PY+ L + ++P MP W++Q GWT+Y T + V P+E L+FDVE +A AV YWYSW S+ L++ E+ DLIPL ++ + + +VGH +SFDRA I+++Y IKG+ RF+DTMSM +AI G+T QR+L ++ + +++ + SP I D W+ +S+N+L DV+ Y L K+ RE F+KG+I DI +FQ LM YCA DV T +IFQ+ + + R PHP + +GMLEMG YLPVN N Y++ A T+YE + K+ K+ LM LA + E Y DPWL WD+ +W + P W+R L K E+ + P LI+ Q + K+++L WDG PLHY +K+ WG L+PG
Sbjct: 13 DVSRRMNPLNIQMLSKGLHAQVFRGKQVQHAEEDIQRSINHLKSHELWGQETSTVPDIELQLPKLYGNDIEEHFQILAQKQSLPYLEAANDLMNCQLPTMPQTWAWQSGWTRY-TATGETELVDFPDEKALVFDVEVCVSEGHCPTLAAAVSPQYWYSWCSRRLIEDRYTWSKELSLSDLIPLETSVNCNCITKNNWTERLVVGHNISFDRAHIKEQYLIKGSKMRFMDTMSMHMAISGLTGFQRTLWMASKYGKKKGLQEVKQHIKKTRSKFDGSP--ISSWD-WVNISSINNLADVHALYVGGPPLE--KEARELFVKGSISDIRTEFQELMRYCALDVQATHEIFQEQFPLFMERCPHPVTLSGMLEMGVSYLPVNQNWERYLDEAQTSYEELQKEMKKSLMNLANDACQLLTEDAYKEDPWLWDLEWDIQEFKQKKTKISKKQKRLKEAQESVGNKFIEDLNEGEWRIEDLKLKTLPLLPKRSQHLPGHPGWYRKLCPKLEDPDWLPGPSLISLQMRLTPKLMRLTWDGFPLHYSEKHGWGYLVPG 556
BLAST of DNA polymerase subunit gamma vs. Ensembl Xenopus
Match: tpst1 (tyrosylprotein sulfotransferase 1 [Source:Xenbase;Acc:XB-GENE-953306]) HSP 1 Score: 418.698 bits (1075), Expect = 1.550e-126 Identity = 223/481 (46.36%), Postives = 282/481 (58.63%), Query Frame = 3
Query: 2127 VWFLPLPHEKGEGNTVGSPFSKSFLNYMQSGRLTSHAANNLLEIMIEGKKSGVFWRNYQNRVQSQFMV--------RT-------SKENNESAIIPQVIVAGTVTRRSVERLWLTATNSTNDRVGSELKAMVQTPTNWVMVGADVDSQEQWIAAVLGDS-VTGIHGGTPFGWMVLQGSKVDGTDLHSKTSKMIGISRNAAKVLNYSRMYGAGIKSSTDTLLKYNPELKPQEAFNKIKDLMKQTKGKR-----------------------------------------------SQGKWVDGIESEVFSKLEEIAKSDEPSTPVLNARLSQALEKRVVNEKFMTSKCNWVVQSSGVDYLHCLLTFTKHLIQLYNVNARLCICIHDEIRYLCEEKDKYRLALILQIANLYTRSVFSMKLNLFDLPQSIAFFSEIDIDYCLRKSPTDDCITPSNQNGLLNNYNIQKGESLNIYQILDKTGGRL 3380
WF LPH+ G N VGSPF+K FL M+ G L + ++ +E K FWRN R+ SQ +V RT +EN I+P V+ AGT+TRR+VE WLTA+N+ DRVGSELKAMVQ P + ++GADVDSQE WIAA+LG++ GIHG T FGWM LQG K GTDLHSKT+ +GISR AKV NY R+YGAG + L+++N L ++A K K + TKG R S+ W G ES++F+KLE IA S P TPVL +S+ALE V +F+TS+ NWVVQSS VDYLH +L K L + Y+++ R CI IHDE+RYL + KD+YR AL LQI NL TR +F+ +L + DLPQS+AFFS +DID CLRK T DC TPSN G+ Y I +GE+L+IYQIL T G L
Sbjct: 696 CWFYKLPHKDGYANNVGSPFAKDFLPKMEDGTLQASIGDSSATRALEINKMISFWRNAHKRISSQMVVWMKKGELPRTITRDPEYDEENKYGCILPLVVSAGTITRRAVEPTWLTASNARADRVGSELKAMVQVPPGYHIIGADVDSQELWIAAILGEAHFAGIHGCTAFGWMTLQGKKSTGTDLHSKTASTVGISREHAKVFNYGRIYGAGQAFAERLLMQFNHRLTQEQAAEKAKQMYAVTKGIRRYILSKEGEWLVEELGIPVERGEENSVSLQDLRKIQKEASAKKWNLVSRRIWTGGTESQMFNKLETIAMSPSPKTPVLGCHISRALEPAAVKGEFITSRINWVVQSSAVDYLHLMLVAMKWLFEAYDIDGRFCISIHDEVRYLVQSKDRYRAALALQITNLLTRCMFASRLGMQDLPQSVAFFSAVDIDKCLRKEVTMDCATPSNPTGMEKRYGIPQGEALDIYQILKVTKGVL 1176 HSP 2 Score: 276.559 bits (706), Expect = 2.947e-76 Identity = 158/427 (37.00%), Postives = 235/427 (55.04%), Query Frame = 3
Query: 225 RINMMNIQMINKKFQETIFGSKST--AELDFFEINSLFKNFKIDTEKTTLNKNVDFDLPPLLGENIEIHLQKAAETLNDPYMALLKGLDDWKIPQMPTMWSFQEGWTKYDTINNKFYKVSVPEENLLIFDVETLPKYTQRAVMAVAVGKSYWYSWTSKYLLDGICKDDSEICKDDLIPLYSN-------DDKSKPKCIVGHFVSFDRARIRDEYCIKGTGTRFIDTMSMQIAIRGMTSLQRSLKISFNNNNTENRIWKLYFSNSSKNGMNNSPEDIEESDKWLTEASLNSLVDVYQYYFPNCNLSSLKDKRETFIKGTIDDIVNDFQALMTYCATDVIMTAKIFQKLWTDYRVRFPHPASFTGMLEMGSLYLPVNSNLNTYINRASTTYESMIKKEKEILMELAQKSLA-SKEKEYINDPWLWDLDW 1475
R+N +NIQM++K +F K AE D + K+ ++ ++T+ +++ LP L G +IE H Q A+ + PY+ L + ++P MP W++Q GWT+Y T + V P+E L+FDVE +A AV YWYSW S+ L++ E+ DLIPL ++ + + +VGH +SFDRA I+++Y IKG+ RF+DTMSM +AI G+T QR+L ++ + +++ + SP I D W+ +S+N+L DV+ Y L K+ RE F+KG+I DI +FQ LM YCA DV T +IFQ+ + + R PHP + +GMLEMG YLPVN N Y++ A T+YE + K+ K+ LM LA + E Y DPWLWDL+W
Sbjct: 44 RMNPLNIQMLSKGLHAQVFRGKQVQHAEEDIQRSINHLKSHELWGQETSTVPDIELQLPKLYGNDIEEHFQILAQKQSLPYLEAANDLMNCQLPTMPQTWAWQSGWTRY-TATGETELVDFPDEKALVFDVEVCVSEGHCPTLAAAVSPQYWYSWCSRRLIEDRYTWSKELSLSDLIPLETSVNCNCITKNNWTERLVVGHNISFDRAHIKEQYLIKGSKMRFMDTMSMHMAISGLTGFQRTLWMASKYGKKKGLQEVKQHIKKTRSKFDGSP--ISSWD-WVNISSINNLADVHALYVGGPPLE--KEARELFVKGSISDIRTEFQELMRYCALDVQATHEIFQEQFPLFMERCPHPVTLSGMLEMGVSYLPVNQNWERYLDEAQTSYEELQKEMKKSLMNLANDACQLLTEDAYKEDPWLWDLEW 464 HSP 3 Score: 60.077 bits (144), Expect = 2.604e-8 Identity = 25/59 (42.37%), Postives = 36/59 (61.02%), Query Frame = 3
Query: 1494 SFPKWFRVLVSKNENSNTF-NPDLITSQKSIAVKMLKLKWDGLPLHYDKKNKWGVLIPG 1667
P W+R L K E+ + P LI+ Q + K+++L WDG PLHY +K+ WG L+PG
Sbjct: 528 GHPGWYRKLCPKLEDPDWLPGPSLISLQMRLTPKLMRLTWDGFPLHYSEKHGWGYLVPG 586
BLAST of DNA polymerase subunit gamma vs. Ensembl Xenopus
Match: tpst1 (tyrosylprotein sulfotransferase 1 [Source:Xenbase;Acc:XB-GENE-953306]) HSP 1 Score: 417.542 bits (1072), Expect = 2.625e-126 Identity = 223/484 (46.07%), Postives = 282/484 (58.26%), Query Frame = 3
Query: 2127 VWFLPLPHEKGEGNTVGSPFSKSFLNYMQSGRLTSHAANNLLEIMIEGKKSGVFWRNYQNRVQSQFMV--------RT-------SKENNESAIIPQVIVAGTVTRRSVERLWLTATNSTNDRVGSELKAMVQTPTNWVMVGADVDSQEQWIAAVLGDS-VTGIHGGTPFGWMVLQGSKVDGTDLHSKTSKMIGISRNAAKVLNYSRMYGAGIKSSTDTLLKYNPELKPQEAFNKIKDLMKQTKGKR--------------------------------------------------SQGKWVDGIESEVFSKLEEIAKSDEPSTPVLNARLSQALEKRVVNEKFMTSKCNWVVQSSGVDYLHCLLTFTKHLIQLYNVNARLCICIHDEIRYLCEEKDKYRLALILQIANLYTRSVFSMKLNLFDLPQSIAFFSEIDIDYCLRKSPTDDCITPSNQNGLLNNYNIQKGESLNIYQILDKTGGRL 3380
WF LPH+ G N VGSPF+K FL M+ G L + ++ +E K FWRN R+ SQ +V RT +EN I+P V+ AGT+TRR+VE WLTA+N+ DRVGSELKAMVQ P + ++GADVDSQE WIAA+LG++ GIHG T FGWM LQG K GTDLHSKT+ +GISR AKV NY R+YGAG + L+++N L ++A K K + TKG R S+ W G ES++F+KLE IA S P TPVL +S+ALE V +F+TS+ NWVVQSS VDYLH +L K L + Y+++ R CI IHDE+RYL + KD+YR AL LQI NL TR +F+ +L + DLPQS+AFFS +DID CLRK T DC TPSN G+ Y I +GE+L+IYQIL T G L
Sbjct: 670 CWFYKLPHKDGYANNVGSPFAKDFLPKMEDGTLQASIGDSSATRALEINKMISFWRNAHKRISSQMVVWMKKGELPRTITRYPFYDEENKYGCILPLVVSAGTITRRAVEPTWLTASNARADRVGSELKAMVQVPPGYHIIGADVDSQELWIAAILGEAHFAGIHGCTAFGWMTLQGKKSTGTDLHSKTASTVGISREHAKVFNYGRIYGAGQAFAERLLMQFNHRLTQEQAAEKAKQMYAVTKGIRRYILSKEGEWLVEELGIPVERGEENSVSLQDLRKIQKEASAKSRRKWNLVSRRIWTGGTESQMFNKLETIAMSPSPKTPVLGCHISRALEPAAVKGEFITSRINWVVQSSAVDYLHLMLVAMKWLFEAYDIDGRFCISIHDEVRYLVQSKDRYRAALALQITNLLTRCMFASRLGMQDLPQSVAFFSAVDIDKCLRKEVTMDCATPSNPTGMEKRYGIPQGEALDIYQILKVTKGVL 1153 HSP 2 Score: 276.559 bits (706), Expect = 2.689e-76 Identity = 158/427 (37.00%), Postives = 235/427 (55.04%), Query Frame = 3
Query: 225 RINMMNIQMINKKFQETIFGSKST--AELDFFEINSLFKNFKIDTEKTTLNKNVDFDLPPLLGENIEIHLQKAAETLNDPYMALLKGLDDWKIPQMPTMWSFQEGWTKYDTINNKFYKVSVPEENLLIFDVETLPKYTQRAVMAVAVGKSYWYSWTSKYLLDGICKDDSEICKDDLIPLYSN-------DDKSKPKCIVGHFVSFDRARIRDEYCIKGTGTRFIDTMSMQIAIRGMTSLQRSLKISFNNNNTENRIWKLYFSNSSKNGMNNSPEDIEESDKWLTEASLNSLVDVYQYYFPNCNLSSLKDKRETFIKGTIDDIVNDFQALMTYCATDVIMTAKIFQKLWTDYRVRFPHPASFTGMLEMGSLYLPVNSNLNTYINRASTTYESMIKKEKEILMELAQKSLA-SKEKEYINDPWLWDLDW 1475
R+N +NIQM++K +F K AE D + K+ ++ ++T+ +++ LP L G +IE H Q A+ + PY+ L + ++P MP W++Q GWT+Y T + V P+E L+FDVE +A AV YWYSW S+ L++ E+ DLIPL ++ + + +VGH +SFDRA I+++Y IKG+ RF+DTMSM +AI G+T QR+L ++ + +++ + SP I D W+ +S+N+L DV+ Y L K+ RE F+KG+I DI +FQ LM YCA DV T +IFQ+ + + R PHP + +GMLEMG YLPVN N Y++ A T+YE + K+ K+ LM LA + E Y DPWLWDL+W
Sbjct: 37 RMNPLNIQMLSKGLHAQVFRGKQVQHAEEDIQRSINHLKSHELWGQETSTVPDIELQLPKLYGNDIEEHFQILAQKQSLPYLEAANDLMNCQLPTMPQTWAWQSGWTRY-TATGETELVDFPDEKALVFDVEVCVSEGHCPTLAAAVSPQYWYSWCSRRLIEDRYTWSKELSLSDLIPLETSVNCNCITKNNWTERLVVGHNISFDRAHIKEQYLIKGSKMRFMDTMSMHMAISGLTGFQRTLWMASKYGKKKGLQEVKQHIKKTRSKFDGSP--ISSWD-WVNISSINNLADVHALYVGGPPLE--KEARELFVKGSISDIRTEFQELMRYCALDVQATHEIFQEQFPLFMERCPHPVTLSGMLEMGVSYLPVNQNWERYLDEAQTSYEELQKEMKKSLMNLANDACQLLTEDAYKEDPWLWDLEW 457 HSP 3 Score: 60.077 bits (144), Expect = 2.612e-8 Identity = 25/59 (42.37%), Postives = 36/59 (61.02%), Query Frame = 3
Query: 1494 SFPKWFRVLVSKNENSNTF-NPDLITSQKSIAVKMLKLKWDGLPLHYDKKNKWGVLIPG 1667
P W+R L K E+ + P LI+ Q + K+++L WDG PLHY +K+ WG L+PG
Sbjct: 521 GHPGWYRKLCPKLEDPDWLPGPSLISLQMRLTPKLMRLTWDGFPLHYSEKHGWGYLVPG 579
BLAST of DNA polymerase subunit gamma vs. Ensembl Xenopus
Match: tpst1 (tyrosylprotein sulfotransferase 1 [Source:Xenbase;Acc:XB-GENE-953306]) HSP 1 Score: 417.542 bits (1072), Expect = 3.167e-126 Identity = 222/484 (45.87%), Postives = 280/484 (57.85%), Query Frame = 3
Query: 2127 VWFLPLPHEKGEGNTVGSPFSKSFLNYMQSGRLTSHAANNLLEIMIEGKKSGVFWRNYQNRVQSQFMVRTSK---------------ENNESAIIPQVIVAGTVTRRSVERLWLTATNSTNDRVGSELKAMVQTPTNWVMVGADVDSQEQWIAAVLGDS-VTGIHGGTPFGWMVLQGSKVDGTDLHSKTSKMIGISRNAAKVLNYSRMYGAGIKSSTDTLLKYNPELKPQEAFNKIKDLMKQTKGKR--------------------------------------------------SQGKWVDGIESEVFSKLEEIAKSDEPSTPVLNARLSQALEKRVVNEKFMTSKCNWVVQSSGVDYLHCLLTFTKHLIQLYNVNARLCICIHDEIRYLCEEKDKYRLALILQIANLYTRSVFSMKLNLFDLPQSIAFFSEIDIDYCLRKSPTDDCITPSNQNGLLNNYNIQKGESLNIYQILDKTGGRL 3380
WF LPH+ G N VGSPF+K FL M+ G L + ++ +E K FWRN R+ SQ +V K EN I+P V+ AGT+TRR+VE WLTA+N+ DRVGSELKAMVQ P + ++GADVDSQE WIAA+LG++ GIHG T FGWM LQG K GTDLHSKT+ +GISR AKV NY R+YGAG + L+++N L ++A K K + TKG R S+ W G ES++F+KLE IA S P TPVL +S+ALE V +F+TS+ NWVVQSS VDYLH +L K L + Y+++ R CI IHDE+RYL + KD+YR AL LQI NL TR +F+ +L + DLPQS+AFFS +DID CLRK T DC TPSN G+ Y I +GE+L+IYQIL T G L
Sbjct: 684 CWFYKLPHKDGYANNVGSPFAKDFLPKMEDGTLQASIGDSSATRALEINKMISFWRNAHKRISSQMVVWMKKGELPRTITRYPFYDEENKYGCILPLVVSAGTITRRAVEPTWLTASNARADRVGSELKAMVQVPPGYHIIGADVDSQELWIAAILGEAHFAGIHGCTAFGWMTLQGKKSTGTDLHSKTASTVGISREHAKVFNYGRIYGAGQAFAERLLMQFNHRLTQEQAAEKAKQMYAVTKGIRRYILSKEGEWLVEELGIPVERGEENSVSLQDLRKIQKEASAKSRRKWNLVSRRIWTGGTESQMFNKLETIAMSPSPKTPVLGCHISRALEPAAVKGEFITSRINWVVQSSAVDYLHLMLVAMKWLFEAYDIDGRFCISIHDEVRYLVQSKDRYRAALALQITNLLTRCMFASRLGMQDLPQSVAFFSAVDIDKCLRKEVTMDCATPSNPTGMEKRYGIPQGEALDIYQILKVTKGVL 1167 HSP 2 Score: 275.789 bits (704), Expect = 5.309e-76 Identity = 157/427 (36.77%), Postives = 233/427 (54.57%), Query Frame = 3
Query: 225 RINMMNIQMINKKFQETIFGSKST--AELDFFEINSLFKNFKIDTEKTTLNKNVDFDLPPLLGENIEIHLQKAAETLNDPYMALLKGLDDWKIPQMPTMWSFQEGWTKYDTINNKFYKVSVPEENLLIFDVETLPKYTQRAVMAVAVGKSYWYSWTSKYLLDGICKDDSEICKDDLIPLYSN-------DDKSKPKCIVGHFVSFDRARIRDEYCIKGTGTRFIDTMSMQIAIRGMTSLQRSLKISFNNNNTENRIWKLYFSNSSKNGMNNSPEDIEESDKWLTEASLNSLVDVYQYYFPNCNLSSLKDKRETFIKGTIDDIVNDFQALMTYCATDVIMTAKIFQKLWTDYRVRFPHPASFTGMLEMGSLYLPVNSNLNTYINRASTTYESMIKKEKEILMELAQKSLA-SKEKEYINDPWLWDLDW 1475
R+N +NIQM++K +F K AE D + K+ ++ ++T+ +++ LP L G +IE H Q A+ + PY+ L + ++P MP W++Q GWT+Y T + V P+E L+FDVE +A AV YWYSW S+ L++ E+ DLIPL ++ + + +VGH +SFDRA I+++Y IKG+ RF+DTMSM +AI G+T QR+L ++ + + + F SS + W+ +S+N+L DV+ Y L K+ RE F+KG+I DI +FQ LM YCA DV T +IFQ+ + + R PHP + +GMLEMG YLPVN N Y++ A T+YE + K+ K+ LM LA + E Y DPWLWDL+W
Sbjct: 44 RMNPLNIQMLSKGLHAQVFRGKQVQHAEEDIQRSINHLKSHELWGQETSTVPDIELQLPKLYGNDIEEHFQILAQKQSLPYLEAANDLMNCQLPTMPQTWAWQSGWTRY-TATGETELVDFPDEKALVFDVEVCVSEGHCPTLAAAVSPQYWYSWCSRRLIEDRYTWSKELSLSDLIPLETSVNCNCITKNNWTERLVVGHNISFDRAHIKEQYLIKGSKMRFMDTMSMHMAISGLTGFQRTLWMASKYGKKKGQDFVRLFQISSWD--------------WVNISSINNLADVHALYVGGPPLE--KEARELFVKGSISDIRTEFQELMRYCALDVQATHEIFQEQFPLFMERCPHPVTLSGMLEMGVSYLPVNQNWERYLDEAQTSYEELQKEMKKSLMNLANDACQLLTEDAYKEDPWLWDLEW 453 HSP 3 Score: 60.077 bits (144), Expect = 2.428e-8 Identity = 25/57 (43.86%), Postives = 36/57 (63.16%), Query Frame = 3
Query: 1500 PKWFRVLVSKNENSNTF-NPDLITSQKSIAVKMLKLKWDGLPLHYDKKNKWGVLIPG 1667
P W+R L K E+ + P LI+ Q + K+++L WDG PLHY +K+ WG L+PG
Sbjct: 519 PGWYRKLCPKLEDPDWLPGPSLISLQMRLTPKLMRLTWDGFPLHYSEKHGWGYLVPG 575
BLAST of DNA polymerase subunit gamma vs. Ensembl Xenopus
Match: tpst1 (tyrosylprotein sulfotransferase 1 [Source:Xenbase;Acc:XB-GENE-953306]) HSP 1 Score: 417.542 bits (1072), Expect = 6.616e-126 Identity = 223/484 (46.07%), Postives = 282/484 (58.26%), Query Frame = 3
Query: 2127 VWFLPLPHEKGEGNTVGSPFSKSFLNYMQSGRLTSHAANNLLEIMIEGKKSGVFWRNYQNRVQSQFMV--------RT-------SKENNESAIIPQVIVAGTVTRRSVERLWLTATNSTNDRVGSELKAMVQTPTNWVMVGADVDSQEQWIAAVLGDS-VTGIHGGTPFGWMVLQGSKVDGTDLHSKTSKMIGISRNAAKVLNYSRMYGAGIKSSTDTLLKYNPELKPQEAFNKIKDLMKQTKGKR--------------------------------------------------SQGKWVDGIESEVFSKLEEIAKSDEPSTPVLNARLSQALEKRVVNEKFMTSKCNWVVQSSGVDYLHCLLTFTKHLIQLYNVNARLCICIHDEIRYLCEEKDKYRLALILQIANLYTRSVFSMKLNLFDLPQSIAFFSEIDIDYCLRKSPTDDCITPSNQNGLLNNYNIQKGESLNIYQILDKTGGRL 3380
WF LPH+ G N VGSPF+K FL M+ G L + ++ +E K FWRN R+ SQ +V RT +EN I+P V+ AGT+TRR+VE WLTA+N+ DRVGSELKAMVQ P + ++GADVDSQE WIAA+LG++ GIHG T FGWM LQG K GTDLHSKT+ +GISR AKV NY R+YGAG + L+++N L ++A K K + TKG R S+ W G ES++F+KLE IA S P TPVL +S+ALE V +F+TS+ NWVVQSS VDYLH +L K L + Y+++ R CI IHDE+RYL + KD+YR AL LQI NL TR +F+ +L + DLPQS+AFFS +DID CLRK T DC TPSN G+ Y I +GE+L+IYQIL T G L
Sbjct: 714 CWFYKLPHKDGYANNVGSPFAKDFLPKMEDGTLQASIGDSSATRALEINKMISFWRNAHKRISSQMVVWMKKGELPRTITRDPEYDEENKYGCILPLVVSAGTITRRAVEPTWLTASNARADRVGSELKAMVQVPPGYHIIGADVDSQELWIAAILGEAHFAGIHGCTAFGWMTLQGKKSTGTDLHSKTASTVGISREHAKVFNYGRIYGAGQAFAERLLMQFNHRLTQEQAAEKAKQMYAVTKGIRRYILSKEGEWLVEELGIPVERGEENSVSLQDLRKIQKEASAKSRRKWNLVSRRIWTGGTESQMFNKLETIAMSPSPKTPVLGCHISRALEPAAVKGEFITSRINWVVQSSAVDYLHLMLVAMKWLFEAYDIDGRFCISIHDEVRYLVQSKDRYRAALALQITNLLTRCMFASRLGMQDLPQSVAFFSAVDIDKCLRKEVTMDCATPSNPTGMEKRYGIPQGEALDIYQILKVTKGVL 1197 HSP 2 Score: 276.559 bits (706), Expect = 3.890e-76 Identity = 158/427 (37.00%), Postives = 235/427 (55.04%), Query Frame = 3
Query: 225 RINMMNIQMINKKFQETIFGSKST--AELDFFEINSLFKNFKIDTEKTTLNKNVDFDLPPLLGENIEIHLQKAAETLNDPYMALLKGLDDWKIPQMPTMWSFQEGWTKYDTINNKFYKVSVPEENLLIFDVETLPKYTQRAVMAVAVGKSYWYSWTSKYLLDGICKDDSEICKDDLIPLYSN-------DDKSKPKCIVGHFVSFDRARIRDEYCIKGTGTRFIDTMSMQIAIRGMTSLQRSLKISFNNNNTENRIWKLYFSNSSKNGMNNSPEDIEESDKWLTEASLNSLVDVYQYYFPNCNLSSLKDKRETFIKGTIDDIVNDFQALMTYCATDVIMTAKIFQKLWTDYRVRFPHPASFTGMLEMGSLYLPVNSNLNTYINRASTTYESMIKKEKEILMELAQKSLA-SKEKEYINDPWLWDLDW 1475
R+N +NIQM++K +F K AE D + K+ ++ ++T+ +++ LP L G +IE H Q A+ + PY+ L + ++P MP W++Q GWT+Y T + V P+E L+FDVE +A AV YWYSW S+ L++ E+ DLIPL ++ + + +VGH +SFDRA I+++Y IKG+ RF+DTMSM +AI G+T QR+L ++ + +++ + SP I D W+ +S+N+L DV+ Y L K+ RE F+KG+I DI +FQ LM YCA DV T +IFQ+ + + R PHP + +GMLEMG YLPVN N Y++ A T+YE + K+ K+ LM LA + E Y DPWLWDL+W
Sbjct: 44 RMNPLNIQMLSKGLHAQVFRGKQVQHAEEDIQRSINHLKSHELWGQETSTVPDIELQLPKLYGNDIEEHFQILAQKQSLPYLEAANDLMNCQLPTMPQTWAWQSGWTRY-TATGETELVDFPDEKALVFDVEVCVSEGHCPTLAAAVSPQYWYSWCSRRLIEDRYTWSKELSLSDLIPLETSVNCNCITKNNWTERLVVGHNISFDRAHIKEQYLIKGSKMRFMDTMSMHMAISGLTGFQRTLWMASKYGKKKGLQEVKQHIKKTRSKFDGSP--ISSWD-WVNISSINNLADVHALYVGGPPLE--KEARELFVKGSISDIRTEFQELMRYCALDVQATHEIFQEQFPLFMERCPHPVTLSGMLEMGVSYLPVNQNWERYLDEAQTSYEELQKEMKKSLMNLANDACQLLTEDAYKEDPWLWDLEW 464 HSP 3 Score: 60.077 bits (144), Expect = 2.683e-8 Identity = 25/59 (42.37%), Postives = 36/59 (61.02%), Query Frame = 3
Query: 1494 SFPKWFRVLVSKNENSNTF-NPDLITSQKSIAVKMLKLKWDGLPLHYDKKNKWGVLIPG 1667
P W+R L K E+ + P LI+ Q + K+++L WDG PLHY +K+ WG L+PG
Sbjct: 540 GHPGWYRKLCPKLEDPDWLPGPSLISLQMRLTPKLMRLTWDGFPLHYSEKHGWGYLVPG 598
BLAST of DNA polymerase subunit gamma vs. Ensembl Mouse
Match: Polg (polymerase (DNA directed), gamma [Source:MGI Symbol;Acc:MGI:1196389]) HSP 1 Score: 454.136 bits (1167), Expect = 2.177e-139 Identity = 273/702 (38.89%), Postives = 364/702 (51.85%), Query Frame = 3
Query: 1494 SFPKWFRVLVSK-NENSNTFNPDLITSQKSIAVKMLKLKWDGLPLHYDKKNKWGVLIPGCYLPVWYDEKFMDISNKLIWPIIPVERISPSYID----YFQFPLQKYVQFWVPLFVSRLEAFRDFLLSLGNSDLTKYNVFVEYMMAIVEPINFTPENLTKVNSLLCEIKEITLRNSKGYYNSNEEGPLSLYNFQMNDFSSLFAKTKCLLTENPIIPFVWFLPLPHEKGEGNTVGSPFSKSFLNYMQSGRLTSHAANNLLEIMIEGKKSGVFWRNYQNRVQSQFMV---RTS------------KENNESAIIPQVIVAGTVTRRSVERLWLTATNSTNDRVGSELKAMVQTPTNWVMVGADVDSQEQWIAAVLGDS-VTGIHGGTPFGWMVLQGSKVDGTDLHSKTSKMIGISRNAAKVLNYSRMYGAGIKSSTDTLLKYNPELKPQEAFNKIKDLMKQTKGKR---------------------------------------------------SQGKWVDGIESEVFSKLEEIAKSDEPSTPVLNARLSQALEKRVVNEKFMTSKCNWVVQSSGVDYLHCLLTFTKHLIQLYNVNARLCICIHDEIRYLCEEKDKYRLALILQIANLYTRSVFSMKLNLFDLPQSIAFFSEIDIDYCLRKSPTDDCITPSNQNGLLNNYNIQKGESLNIYQILDKTGGRLD 3383
P W+R L + ++ + P L++ Q + K++ L WDG PLHY + WG L+PG + +++ + P + ++ Y Y + L++ Q P V E +FLL+ D + VE + + EN L+ + Y++ N GP + N IP WF LPH+ G VGSPF+K FL M+ G L + +E K FWRN R+ SQ +V R++ +E + AI+PQV+ AGT+TRR+VE WLTA+N+ DRVGSELKAMVQ P +V+VGADVDSQE WIAAVLGD+ G+HG T FGWM LQG K GTDLHSKT+ +GISR AK+ NY R+YGAG + L+++N L QEA K + + TKG R S+ W G ESE+F+KLE IA SD P TPVL +S+ALE VV +F+TS+ NWVVQSS VDYLH +L K L + + ++ R CI IHDE+RYL E+D+YR AL LQI NL TR +F+ KL L DLPQS+AFFS +DID CLRK T DC TPSN G+ Y I +GE+L+IYQI++ T G L+
Sbjct: 549 GHPGWYRKLCPRLDDPAWAPGPSLLSLQMRVTPKLMALTWDGFPLHYSDSHGWGYLVPG---------RRDNLTEPPVSPTVESAAVTCPYRAIESLYRKHCLEQGKQQLEPQEVDLAE---EFLLT----DSSAMWQTVEELGCLDVEAEAKMENSGLSQPLVLPAACAPKSSQPTYHHGN--GPYNDVN----------------------IPGCWFFKLPHKDGNNYNVGSPFAKDFLPKMEDGTLQAGPGGASGPRALEINKMISFWRNAHKRISSQMVVWLPRSALPRVVTRHPSFDEEGHYGAILPQVVTAGTITRRAVEPTWLTASNARPDRVGSELKAMVQAPPGYVLVGADVDSQELWIAAVLGDAHFAGMHGCTAFGWMTLQGRKSRGTDLHSKTAATVGISREHAKIFNYGRIYGAGQSFAERLLMQFNHRLTRQEAAEKAQQMYAVTKGLRRYRLSADGEWLVKQLNLPVDRTEDGWVSLQDLRMIRREASRKSRWKKWEVASERAWTGGTESEMFNKLESIAMSDTPRTPVLGCCISRALEPSVVQGEFITSRVNWVVQSSAVDYLHLMLVAMKWLFEEFAIDGRFCISIHDEVRYLVREEDRYRAALALQITNLLTRCMFAYKLGLNDLPQSVAFFSAVDIDQCLRKEVTMDCKTPSNPTGMERRYGIPQGEALDIYQIIELTKGSLE 1210 HSP 2 Score: 268.855 bits (686), Expect = 1.233e-73 Identity = 163/459 (35.51%), Postives = 243/459 (52.94%), Query Frame = 3
Query: 138 RFLSYSGYLPKPSNFGRLLNTANSSDDKLRINMMNIQMINKKFQETIFGSKSTAELDFFEINSL--FKNFKIDTEKTTLNKNVDFDLPPLLGENIEIHLQKAAETLNDPYMALLKGLDDWKIPQMPTMWSFQEGWTKYDTINNKFYKVSVPEENLLIFDVETLPKYTQRAVMAVAVGKSYWYSWTSKYLLDGICKDDSEICKDDLIPLYSN-------DDKSKPKCIVGHFVSFDRARIRDEYCIKGTGTRFIDTMSMQIAIRGMTSLQRSLKISF--NNNNTENRIWKLYFSNSSKNGMNNSPEDIEESDKWLTEASLNSLVDVYQYYFPNCNLSSLKDKRETFIKGTIDDIVNDFQALMTYCATDVIMTAKIFQKLWTDYRVRFPHPASFTGMLEMGSLYLPVNSNLNTYINRASTTYESMIKKEKEILMELAQKS--LASKEKEYINDPWLWDLDW 1475
R++S S P PS+ +S + +LR+N + IQM+++ E IFG + S+ + + + T +V+ LP L G N++ H + A+ + PY+ L + ++P P W++ EGWT+Y + V++PEE L+FDVE +AVA+ S WYSW S+ L++ S++ DLIPL + + + +VGH VSFDRA IR++Y I+ + RF+DTMSM +AI G++S QRSL + + T+ + S NG S D W+ +S N+L DV+ Y L K+ RE F+KG++ DI +FQ LM YCA DV T ++FQ+ + R PHP + GMLEMG YLPVN N Y+ A TYE + ++ K+ LM+LA + L S E+ Y DPWLWDL+W
Sbjct: 24 RWVSSSVLDPVPSDGRPPSQMPSSENGQLRLNPLLIQMLSRGLHEQIFGCGGEMPDEAAVQRSVEHLQKHGLWGQPATPLPDVELRLPRLFGGNLDQHFRLLAQKQSLPYLEAAASLLEAQLPPEPKSWAWAEGWTRYGP-EGEAEPVAIPEERALVFDVEVCLAEGTCPTLAVAISPSAWYSWCSRRLVEERYSWTSQLSPADLIPLGGSTSASSSTKQDGQEQLVVGHNVSFDRAHIREQYLIQDSRMRFLDTMSMHMAISGLSSFQRSLWMGAKQGKHKTQQSTKRGQKSPRKANGPAISSWD------WMDISSANNLADVHNLYVGGPPLE--KEPRELFVKGSMRDIRENFQDLMQYCARDVWATFEVFQQQLPLFLERCPHPVTLAGMLEMGVSYLPVNQNWERYLTEAQNTYEELQREMKKSLMDLANDACQLLSGER-YKEDPWLWDLEW 472
BLAST of DNA polymerase subunit gamma vs. Ensembl Mouse
Match: Polg (polymerase (DNA directed), gamma [Source:MGI Symbol;Acc:MGI:1196389]) HSP 1 Score: 268.085 bits (684), Expect = 1.867e-78 Identity = 163/459 (35.51%), Postives = 243/459 (52.94%), Query Frame = 3
Query: 138 RFLSYSGYLPKPSNFGRLLNTANSSDDKLRINMMNIQMINKKFQETIFGSKSTAELDFFEINSL--FKNFKIDTEKTTLNKNVDFDLPPLLGENIEIHLQKAAETLNDPYMALLKGLDDWKIPQMPTMWSFQEGWTKYDTINNKFYKVSVPEENLLIFDVETLPKYTQRAVMAVAVGKSYWYSWTSKYLLDGICKDDSEICKDDLIPLYSN-------DDKSKPKCIVGHFVSFDRARIRDEYCIKGTGTRFIDTMSMQIAIRGMTSLQRSLKISF--NNNNTENRIWKLYFSNSSKNGMNNSPEDIEESDKWLTEASLNSLVDVYQYYFPNCNLSSLKDKRETFIKGTIDDIVNDFQALMTYCATDVIMTAKIFQKLWTDYRVRFPHPASFTGMLEMGSLYLPVNSNLNTYINRASTTYESMIKKEKEILMELAQKS--LASKEKEYINDPWLWDLDW 1475
R++S S P PS+ +S + +LR+N + IQM+++ E IFG + S+ + + + T +V+ LP L G N++ H + A+ + PY+ L + ++P P W++ EGWT+Y + V++PEE L+FDVE +AVA+ S WYSW S+ L++ S++ DLIPL + + + +VGH VSFDRA IR++Y I+ + RF+DTMSM +AI G++S QRSL + + T+ + S NG S D W+ +S N+L DV+ Y L K+ RE F+KG++ DI +FQ LM YCA DV T ++FQ+ + R PHP + GMLEMG YLPVN N Y+ A TYE + ++ K+ LM+LA + L S E+ Y DPWLWDL+W
Sbjct: 24 RWVSSSVLDPVPSDGRPPSQMPSSENGQLRLNPLLIQMLSRGLHEQIFGCGGEMPDEAAVQRSVEHLQKHGLWGQPATPLPDVELRLPRLFGGNLDQHFRLLAQKQSLPYLEAAASLLEAQLPPEPKSWAWAEGWTRYGP-EGEAEPVAIPEERALVFDVEVCLAEGTCPTLAVAISPSAWYSWCSRRLVEERYSWTSQLSPADLIPLGGSTSASSSTKQDGQEQLVVGHNVSFDRAHIREQYLIQDSRMRFLDTMSMHMAISGLSSFQRSLWMGAKQGKHKTQQSTKRGQKSPRKANGPAISSWD------WMDISSANNLADVHNLYVGGPPLE--KEPRELFVKGSMRDIRENFQDLMQYCARDVWATFEVFQQQLPLFLERCPHPVTLAGMLEMGVSYLPVNQNWERYLTEAQNTYEELQREMKKSLMDLANDACQLLSGER-YKEDPWLWDLEW 472
BLAST of DNA polymerase subunit gamma vs. Ensembl Mouse
Match: Polg (polymerase (DNA directed), gamma [Source:MGI Symbol;Acc:MGI:1196389]) HSP 1 Score: 113.235 bits (282), Expect = 3.419e-29 Identity = 53/90 (58.89%), Postives = 63/90 (70.00%), Query Frame = 3
Query: 3078 ICIHDEIRYLCEEKDKYRLALILQIANLYTRSVFSMKLNLFDLPQSIAFFSEIDIDYCLRKSPTDDCITPSNQNGLLNNYNIQKGESLNI 3347
I IHDE+RYL E+D+YR AL LQI NL TR +F+ KL L DLPQS+AFFS +DID CLRK T DC TPSN G+ Y I +G L +
Sbjct: 2 ISIHDEVRYLVREEDRYRAALALQITNLLTRCMFAYKLGLNDLPQSVAFFSAVDIDQCLRKEVTMDCKTPSNPTGMERRYGIPQGCDLEL 91
BLAST of DNA polymerase subunit gamma vs. Ensembl Mouse
Match: Polg (polymerase (DNA directed), gamma [Source:MGI Symbol;Acc:MGI:1196389]) HSP 1 Score: 115.161 bits (287), Expect = 4.481e-29 Identity = 63/153 (41.18%), Postives = 81/153 (52.94%), Query Frame = 3
Query: 2742 KYNPELKPQEAFNKIKDLMKQTKGKR-------------------------------SQGKWVDGIESEVFSKLEEIAKSDEPSTPVLNARLSQALEKRVVNEKFMTSKCNWVVQSSGVDYLHCLLTFTKHLIQLYNVNARLCICIHDEIRYL 3107
++N L QEA K + + TKG R S+ W G ESE+F+KLE IA SD P TPVL +S+ALE VV +F+TS+ NWVVQSS VDYLH +L K L + + ++ R CI IHDE+RYL
Sbjct: 2 QFNHRLTRQEAAEKAQQMYAVTKGLRRTEDGWVSLQDLRMIRREASRKSRWKKWEVASERAWTGGTESEMFNKLESIAMSDTPRTPVLGCCISRALEPSVVQGEFITSRVNWVVQSSAVDYLHLMLVAMKWLFEEFAIDGRFCISIHDEVRYL 154
BLAST of DNA polymerase subunit gamma vs. Ensembl Mouse
Match: Polg (polymerase (DNA directed), gamma [Source:MGI Symbol;Acc:MGI:1196389]) HSP 1 Score: 85.8853 bits (211), Expect = 6.787e-18 Identity = 52/181 (28.73%), Postives = 88/181 (48.62%), Query Frame = 3
Query: 138 RFLSYSGYLPKPSNFGRLLNTANSSDDKLRINMMNIQMINKKFQETIFGSKSTAELDFFEINSL--FKNFKIDTEKTTLNKNVDFDLPPLLGENIEIHLQKAAETLNDPYMALLKGLDDWKIPQMPTMWSFQEGWTKYDTINNKFYKVSVPEENLLIFDVETLPKYTQRAVMAVAVGKSYW 674
R++S S P PS+ +S + +LR+N + IQM+++ E IFG + S+ + + + T +V+ LP L G N++ H + A+ + PY+ L + ++P P W++ EGWT+Y + V++PEE L+FDVE +AVA+ S W
Sbjct: 24 RWVSSSVLDPVPSDGRPPSQMPSSENGQLRLNPLLIQMLSRGLHEQIFGCGGEMPDEAAVQRSVEHLQKHGLWGQPATPLPDVELRLPRLFGGNLDQHFRLLAQKQSLPYLEAAASLLEAQLPPEPKSWAWAEGWTRYGP-EGEAEPVAIPEERALVFDVEVCLAEGTCPTLAVAISPSAW 203
BLAST of DNA polymerase subunit gamma vs. UniProt/SwissProt
Match: sp|Q92076|DPOG1_CHICK (DNA polymerase subunit gamma-1 (Fragment) OS=Gallus gallus OX=9031 GN=POLG PE=2 SV=1) HSP 1 Score: 457.988 bits (1177), Expect = 2.813e-146 Identity = 273/683 (39.97%), Postives = 363/683 (53.15%), Query Frame = 3
Query: 1551 NPDLITSQKSIAVKMLKLKWDGLPLHYDKKNKWGVLIPGCYLPVWYDEKFMDISNKLIWPIIP---VERISPSYIDYFQFPLQKYVQFWVPLFVSRLEAFRDFLLSL-GNSDLTKYNVFVEYMMAIVEPINFTPENLTKVNSLLCEIKEITLRNSKGYYNSNEEGPLSLYNFQMNDFSSLFAKTKCLLTENPIIPFVWFLPLPHEKGEGNTVGSPFSKSFLNYMQSGRLTSHAANNLLEIMIEGKKSGVFWRNYQNRVQSQFMV---------------RTSKENNESAIIPQVIVAGTVTRRSVERLWLTATNSTNDRVGSELKAMVQTPTNWVMVGADVDSQEQWIAAVLGDS-VTGIHGGTPFGWMVLQGSKVDGTDLHSKTSKMIGISRNAAKVLNYSRMYGAGIKSSTDTLLKYNPELKPQEAFNKIKDLMKQTKGKR-----SQGKWV-----------------------------------------------DGIESEVFSKLEEIAKSDEPSTPVLNARLSQALEKRVVNEKFMTSKCNWVVQSSGVDYLHCLLTFTKHLIQLYNVNARLCICIHDEIRYLCEEKDKYRLALILQIANLYTRSVFSMKLNLFDLPQSIAFFSEIDIDYCLRKSPTDDCITPSNQNGLLNNYNIQKGESLNIYQILDKTGGRLD 3383
P LI+ Q + K+++L WDG PLHY +K+ WG L+PG + S + P+ P +ER+ Y Q LQ+ + P + +E D L+ L G+S K + + + P + + L ++E + +++ N GP + N IP WF LPH+ G N VGSPF+K FL M+ G L + +E K FWRN RV SQ +V S+E + AI+PQV+ AGT+TRR+VE WLTA+N+ DRVGSELKAMVQ P + +VGADVDSQE WIAAVLG++ G+HG T FGWM LQG K DGTDLHSKT+ +GISR AKV NY R+YGAG + L+++N L Q+A K + + TKG R +G+W+ G ESE+F+KLE IA S P TPVL +S+ALE V +F+TS+ NWVVQSS VDYLH +L K L + Y++N R CI IHDE+RYL +E+D+YR AL LQI NL TR +F+ KL L DLPQS+AFFS +DID CLRK T +C TPSN G+ Y I +GE+L+IYQI++ T G L+
Sbjct: 7 GPSLISLQMRVTPKLMRLAWDGFPLHYSEKHGWGYLVPG------RQDNLPAASAEPEGPVCPHRAIERL------YRQHCLQRGQE--QPPEEAGVE---DELMVLEGSSMWQKVEELSQLELDMERPGRAEQSQMQDEDGLPELVEE---SSQPSFHHGN--GPYNDVN----------------------IPGCWFFKLPHKDGNENNVGSPFAKDFLPRMEDGTLRAAVGRTHGTRALEINKMVSFWRNAHKRVSSQVVVWLKKGELPRAVTRHPAYSEEEDYGAILPQVVTAGTITRRAVEPTWLTASNARADRVGSELKAMVQVPPGYSLVGADVDSQELWIAAVLGEAHFAGMHGCTAFGWMTLQGKKSDGTDLHSKTAATVGISREHAKVFNYGRIYGAGQPFAERLLMQFNHRLTQQQAREKAQQMYAVTKGIRRFHLSEEGEWLVKELELAVDKAEDGTVSAQDVQKIQREAMRKSRRKKKWDVVAHRMWAGGTESEMFNKLESIALSASPQTPVLGCHISRALEPAVAKGEFLTSRVNWVVQSSAVDYLHLMLVSMKWLFEEYDINGRFCISIHDEVRYLVQEQDRYRAALALQITNLLTRCMFAYKLGLQDLPQSVAFFSAVDIDRCLRKEVTMNCATPSNPTGMEKKYGIPRGEALDIYQIIEITKGSLE 645
BLAST of DNA polymerase subunit gamma vs. UniProt/SwissProt
Match: sp|Q91684|DPOG1_XENLA (DNA polymerase subunit gamma-1 OS=Xenopus laevis OX=8355 GN=polg PE=2 SV=1) HSP 1 Score: 448.358 bits (1152), Expect = 1.396e-136 Identity = 277/700 (39.57%), Postives = 369/700 (52.71%), Query Frame = 3
Query: 1494 SFPKWFRVLVSKNENSNTF-NPDLITSQKSIAVKMLKLKWDGLPLHYDKKNKWGVLIPGCYLPVWYDEKFMDISNKLIWPIIPVERISPSYIDYFQFPLQKYVQFWVPLFVSRLEAFRDFLLSLGNSDLTKYNVFVEYMMAIVEPINFTPENLTKVNSLLCEIKEITLRNSKGYYNSNEEGPLSLYNFQMNDFSSL----FAKTKCLLTENPIIPFVWFLPLPHEKGEGNTVGSPFSKSFLNYMQSGRLTSHAANNLLEIMIEGKKSGVFWRNYQNRVQSQFMV--------RT-------SKENNESAIIPQVIVAGTVTRRSVERLWLTATNSTNDRVGSELKAMVQTPTNWVMVGADVDSQEQWIAAVLGDS-VTGIHGGTPFGWMVLQGSKVDGTDLHSKTSKMIGISRNAAKVLNYSRMYGAGIKSSTDTLLKYNPELKPQEAFNKIKDLMKQTKG------------------------------------------KRSQGK--------WVDGIESEVFSKLEEIAKSDEPSTPVLNARLSQALEKRVVNEKFMTSKCNWVVQSSGVDYLHCLLTFTKHLIQLYNVNARLCICIHDEIRYLCEEKDKYRLALILQIANLYTRSVFSMKLNLFDLPQSIAFFSEIDIDYCLRKSPTDDCITPSNQNGLLNNYNIQKGESLNIYQILDKTGGRL 3380
P W+R L K E+ + P LI+ Q + K+++L WDG PLHY +K+ WG L+ P + K + + I P P I Y +Y + + +F+L+ NS M VE ++ T +L+ E+ N++ E P+ L +M +F SL + C + + WF LPH+ G N VGSPF+K FL M+ G L + ++ +E K FWRN R+ SQ +V RT +EN AI+ QV+ AGT+TRR+VE WLTA+N+ DRVGSELKAMVQ P + ++GADVDSQE WIAA+LG++ GIHG T FGWM LQG K GTDLHSKT+ +GISR AKV NY R+YGAG + L+++N L ++A K K + TKG KRS+ K W G ES++F+KLE IA S P TPVL R+S+ALE V +F+TS+ NWVVQSS VDYLH +L K L + Y+++ R CI IHDE+RYL KD+YR AL LQI NL TR +F+ +L + D+PQS+AFFS +DID CLRK T DC TPSN NG+ Y I +GE+L+IYQIL T G L
Sbjct: 540 GHPGWYRKLCPKLEDPDWLPGPGLISLQMRLTPKLMRLTWDGYPLHYSEKHGWGYLV-----PGRKNNKLNNEEEEEIIPC-PYRAIEDIYAEYSKNKTKDGC------LSQHSTIPEEFMLTDDNS-----------MWQKVEELSRTEMDLSS---------EVPATAKAKKRNNSSEHPVKL---EM-EFDSLPDNHHGNSPC---GDVNVSGCWFYKLPHKDGNANNVGSPFAKDFLPKMEDGTLQASTGDSSATRALEINKMISFWRNAHKRISSQMVVWMKKNELHRTITRDPEFDEENKYGAILAQVVSAGTITRRAVEPTWLTASNARADRVGSELKAMVQVPPGYHLIGADVDSQELWIAAILGEAHFAGIHGCTAFGWMTLQGKKSSGTDLHSKTASTVGISREHAKVFNYGRIYGAGQPFAERLLMQFNHRLTQEQAAEKAKQMYAVTKGIRRYILSKEGEWLVEELGISVERGEENSVNLQDLRKIQKDATKRSRRKWNLVSRRIWTGGTESQMFNKLETIAMSPSPKTPVLGCRISRALEPTAVKGEFITSRVNWVVQSSAVDYLHLMLVAMKWLFEAYDIDGRFCISIHDEVRYLVHSKDRYRAALALQITNLLTRCMFASRLGIQDVPQSVAFFSAVDIDKCLRKEVTMDCSTPSNPNGMEKRYGIPQGEALDIYQILKVTKGVL 1200 HSP 2 Score: 284.263 bits (726), Expect = 5.567e-78 Identity = 162/427 (37.94%), Postives = 237/427 (55.50%), Query Frame = 3
Query: 225 RINMMNIQMINKKFQETIFGSKST--AELDFFEINSLFKNFKIDTEKTTLNKNVDFDLPPLLGENIEIHLQKAAETLNDPYMALLKGLDDWKIPQMPTMWSFQEGWTKYDTINNKFYKVSVPEENLLIFDVETLPKYTQRAVMAVAVGKSYWYSWTSKYLLDGICKDDSEICKDDLIPL-------YSNDDKSKPKCIVGHFVSFDRARIRDEYCIKGTGTRFIDTMSMQIAIRGMTSLQRSLKISFNNNNTENRIWKLYFSNSSKNGMNNSPEDIEESDKWLTEASLNSLVDVYQYYFPNCNLSSLKDKRETFIKGTIDDIVNDFQALMTYCATDVIMTAKIFQKLWTDYRVRFPHPASFTGMLEMGSLYLPVNSNLNTYINRASTTYESMIKKEKEILMELAQKSLASKEKE-YINDPWLWDLDW 1475
R+N +NIQM++K F E IF K AE D + KN ++ ++T+ +V+ LP + G NIE H Q A+ + PY+ L + ++P MP W++Q GWT+Y K V P+E ++FDVE +AVA WYSW S+ L++G E+ DL PL Y + + +VGH VSFDRA I+++Y IKG+ TRF+DTMSM +AI G+T QR+L ++ + +++ + SP I D W+ +S+N+L DV+ Y L K+ RE F+KG++ DI +FQ LM YCA DV T ++FQ+ + + R PHP + +GMLEMG YLPVN N Y++ A T+YE + K+ K+ LM+LA + K+ Y DPWLWDL+W
Sbjct: 44 RMNPLNIQMLSKGFHEQIFRGKQVQHAEEDVQRSITHLKNHELWGQETSTVPDVELQLPKMYGNNIEEHFQILAQKQSLPYLEAANDLLNCQLPAMPQTWAWQSGWTRYTATGEKEL-VDFPDEKAMVFDVEVCVTEGCCPTLAVAASPQNWYSWCSRRLIEGRYTWSKELLLSDLFPLETSMNCNYMTKNNWTERLVVGHNVSFDRAHIKEQYLIKGSKTRFMDTMSMHMAISGLTGFQRTLWMASKYGKKKGLQEVKQHIKKTRSNFSGSP--ISSWD-WVNISSINNLADVHALYVGGPPLE--KEARELFVKGSMSDIRTEFQELMRYCALDVQATHEVFQEQFPLFMERCPHPVTLSGMLEMGVSYLPVNQNWERYLDEAQTSYEELQKEMKKSLMKLANDACQLLTKDAYKEDPWLWDLEW 464
BLAST of DNA polymerase subunit gamma vs. UniProt/SwissProt
Match: sp|P54099|DPOG1_MOUSE (DNA polymerase subunit gamma-1 OS=Mus musculus OX=10090 GN=Polg PE=1 SV=3) HSP 1 Score: 443.736 bits (1140), Expect = 1.325e-134 Identity = 272/702 (38.75%), Postives = 364/702 (51.85%), Query Frame = 3
Query: 1494 SFPKWFRVLVSK-NENSNTFNPDLITSQKSIAVKMLKLKWDGLPLHYDKKNKWGVLIPGCYLPVWYDEKFMDISNKLIWPIIPVERISPSYID----YFQFPLQKYVQFWVPLFVSRLEAFRDFLLSLGNSDLTKYNVFVEYMMAIVEPINFTPENLTKVNSLLCEIKEITLRNSKGYYNSNEEGPLSLYNFQMNDFSSLFAKTKCLLTENPIIPFVWFLPLPHEKGEGNTVGSPFSKSFLNYMQSGRLTSHAANNLLEIMIEGKKSGVFWRNYQNRVQSQFMV---RTS------------KENNESAIIPQVIVAGTVTRRSVERLWLTATNSTNDRVGSELKAMVQTPTNWVMVGADVDSQEQWIAAVLGDS-VTGIHGGTPFGWMVLQGSKVDGTDLHSKTSKMIGISRNAAKVLNYSRMYGAGIKSSTDTLLKYNPELKPQEAFNKIKDLMKQTKGKR---------------------------------------------------SQGKWVDGIESEVFSKLEEIAKSDEPSTPVLNARLSQALEKRVVNEKFMTSKCNWVVQSSGVDYLHCLLTFTKHLIQLYNVNARLCICIHDEIRYLCEEKDKYRLALILQIANLYTRSVFSMKLNLFDLPQSIAFFSEIDIDYCLRKSPTDDCITPSNQNGLLNNYNIQKGESLNIYQILDKTGGRLD 3383
P W+R L + ++ + P L++ Q + K++ L WDG PLHY + W G +P D +++ + P + ++ Y Y + L++ Q P V E +FLL+ NS + + VE + + EN L+ + Y++ N GP + N IP WF LPH+ G VGSPF+K FL M+ G L + +E K FWRN R+ SQ +V R++ +E + AI+PQV+ AGT+TRR+VE WLTA+N+ DRVGSELKAMVQ P +V+VGADVDSQE WIAAVLGD+ G+HG T FGWM LQG K GTDLHSKT+ +GISR AK+ NY R+YGAG + L+++N L QEA K + + TKG R ++ W G ESE+F+KLE IA SD P TPVL +S+ALE VV +F+TS+ NWVVQSS VDYLH +L K L + + ++ R CI IHDE+RYL E+D+YR AL LQI NL TR +F+ KL L DLPQS+AFFS +DID CLRK T DC TPSN G+ Y I +GE+L+IYQI++ T G L+
Sbjct: 550 GHPGWYRQLCPRLDDPAWAPGPSLLSLQMRVTPKLMALTWDGFPLHYSDSHGW-----GYLVPGRRD----NLTEPPVSPTVESAAVTCPYRAIESLYRKHCLEQGKQQLEPQEVDLAE---EFLLT-DNSAMWQT---VEELGCLDVEAEAKMENSGLSQPLVLPAACAPKSSQPTYHHGN--GPYNDVN----------------------IPGCWFFKLPHKDGNNYNVGSPFAKDFLPKMEDGTLQAGPGGASGPRALEINKMISFWRNAHKRISSQMVVWLPRSALPRVVTRHPAFDEEGHYGAILPQVVTAGTITRRAVEPTWLTASNARPDRVGSELKAMVQAPPGYVLVGADVDSQELWIAAVLGDAHFAGMHGCTAFGWMTLQGRKSRGTDLHSKTAATVGISREHAKIFNYGRIYGAGQSFAERLLMQFNHRLTRQEAAEKAQQMYAVTKGLRRYRLSADGEWLVKQLNLPVDRTEDGWVSLQDLRMIRREASRKSRWKKWEVAAERAWTGGTESEMFNKLESIAMSDTPRTPVLGCCISRALEPSVVQGEFITSRVNWVVQSSAVDYLHLMLVAMKWLFEEFAIDGRFCISIHDEVRYLVREEDRYRAALALQITNLLTRCMFAYKLGLNDLPQSVAFFSAVDIDQCLRKEVTMDCKTPSNPTGMERRYGIPQGEALDIYQIIELTKGSLE 1211 HSP 2 Score: 259.61 bits (662), Expect = 8.884e-70 Identity = 158/457 (34.57%), Postives = 240/457 (52.52%), Query Frame = 3
Query: 138 RFLSYSGYLPKPSNFGRLLNTANSSDDKLRINMMNIQMINKKFQETIFGSKSTAELDFFEINSL--FKNFKIDTEKTTLNKNVDFDLPPLLGENIEIHLQKAAETLNDPYMALLKGLDDWKIPQMPTMWSFQEGWTKYDTINNKFYKVSVPEENLLIFDVETLPKYTQRAVMAVAVGKSYWYSWTSKYLLDGICKDDSEICKDDLIPLYSN-------DDKSKPKCIVGHFVSFDRARIRDEYCIKGTGTRFIDTMSMQIAIRGMTSLQRSLKISFNNNNTENRIWKLYFSNSSKNGMNNSPEDIEESDKWLTEASLNSLVDVYQYYFPNCNLSSLKDKRETFIKGTIDDIVNDFQALMTYCATDVIMTAKIFQKLWTDYRVRFPHPASFTGMLEMGSLYLPVNSNLNTYINRASTTYESMIKKEKEILMELAQKS--LASKEKEYINDPWLWDLDW 1475
R+++ S P PS+ +S + +LR+N + IQM+++ E IFG + S+ + + + T +V+ LP L G N++ H + A+ + PY+ L + ++P P W++ EGWT+Y + V++PEE L+FDVE +AVA+ S WYSW S+ L++ S++ DLIPL + + + +VGH VSFDRA IR++Y I+ + RF+DTMSM +AI G++S QRSL + +N ++ + S W+ +S N+L DV+ Y L K+ RE F+KG++ DI +FQ LM YCA DV T ++FQ+ + R PHP + GMLEMG YLPVN N Y+ A TYE + ++ K+ LM+LA + L S E+ Y DPWLWDL+W
Sbjct: 24 RWVASSVLDPVPSDGRPPSQMPSSENGQLRLNPLLIQMLSRGLHEQIFGCGGEMPDEAAVQRSVEHLQKHGLWGQPATPLPDVELRLPRLFGGNLDQHFRLLAQKQSLPYLEAAASLLEAQLPPEPKSWAWAEGWTRYGP-EGEAEPVAIPEERALVFDVEVCLAEGTCPTLAVAISPSAWYSWCSRRLVEERYSWTSQLSPADLIPLGGSTSASSSTKQDGQEQLVVGHNVSFDRAHIREQYLIQDSRMRFLDTMSMHMAISGLSSFQRSLWMGAKQGKHKN---PAAHKARAEVPEESQWSSESSSWDWMDISSANNLADVHNLYVGGPPLE--KEPRELFVKGSMRDIRENFQDLMQYCARDVWATFEVFQQQLPLFLERCPHPVTLAGMLEMGVSYLPVNQNWERYLTEAQNTYEELQREMKKSLMDLANDACQLLSGER-YKEDPWLWDLEW 473
BLAST of DNA polymerase subunit gamma vs. UniProt/SwissProt
Match: sp|Q9QYV8|DPOG1_RAT (DNA polymerase subunit gamma-1 OS=Rattus norvegicus OX=10116 GN=Polg PE=2 SV=1) HSP 1 Score: 432.18 bits (1110), Expect = 1.792e-130 Identity = 231/489 (47.24%), Postives = 290/489 (59.30%), Query Frame = 3
Query: 2118 IPFVWFLPLPHEKGEGNTVGSPFSKSFLNYMQSGRLTSHAANNLLEIMIEGKKSGVFWRNYQNRVQSQFMV---RTS------------KENNESAIIPQVIVAGTVTRRSVERLWLTATNSTNDRVGSELKAMVQTPTNWVMVGADVDSQEQWIAAVLGDS-VTGIHGGTPFGWMVLQGSKVDGTDLHSKTSKMIGISRNAAKVLNYSRMYGAGIKSSTDTLLKYNPELKPQEAFNKIKDLMKQTKGKR---------------------------------------------------SQGKWVDGIESEVFSKLEEIAKSDEPSTPVLNARLSQALEKRVVNEKFMTSKCNWVVQSSGVDYLHCLLTFTKHLIQLYNVNARLCICIHDEIRYLCEEKDKYRLALILQIANLYTRSVFSMKLNLFDLPQSIAFFSEIDIDYCLRKSPTDDCITPSNQNGLLNNYNIQKGESLNIYQILDKTGGRLD 3383
IP WF LPH+ G VGSPF+K FL M+ G L + +E K FWRN R+ SQ +V R++ +E++ AI+PQV+ AGT+TRR+VE WLTA+N+ DRVGSELKAMVQ P +V+VGADVDSQE WIAAVLGD+ G+HG T FGWM LQG K GTDLHSKT+ +GISR AKV NY R+YGAG + L+++N L QEA +K + + TKG R ++ W G ESE+F+KLE IA SD P TPVL +S+ALE VV +FMTS+ NWVVQSS VDYLH +L K L + + ++ R CI IHDE+RYL E+D+YR AL LQI NL TR +F+ KL L DLPQS+AFFS +DID CLRK T DC TPSN G+ Y I +GE+L+IYQI++ T G L+
Sbjct: 721 IPGCWFFKLPHKDGNNYNVGSPFAKDFLPKMEDGTLQAGPGGARGPRALEINKMISFWRNAHKRISSQMVVWLPRSALPRAVTRHPSFDEESHYGAILPQVVTAGTITRRAVEPTWLTASNARPDRVGSELKAMVQAPPGYVLVGADVDSQELWIAAVLGDAHFAGMHGCTAFGWMTLQGRKSRGTDLHSKTAATVGISREHAKVFNYGRIYGAGQSFAERLLMQFNHRLSRQEAADKAQQMYAVTKGLRRYRLSDDGEWLVKQLNVPVDRTEDGWVSLQDLRKIRREASRKSRWKKWEVVTERAWTGGTESEMFNKLESIAMSDTPRTPVLGCCISRALEPSVVQGEFMTSRVNWVVQSSAVDYLHLMLVAMKWLFEEFAIDGRFCISIHDEVRYLVREEDRYRAALALQITNLLTRCMFAYKLGLNDLPQSVAFFSAVDIDQCLRKEVTMDCKTPSNPTGMERKYGIPQGEALDIYQIIELTKGSLE 1209 HSP 2 Score: 280.026 bits (715), Expect = 1.551e-76 Identity = 168/457 (36.76%), Postives = 246/457 (53.83%), Query Frame = 3
Query: 138 RFLSYSGYLPKPSNFGRLLNTANSSDDKLRINMMNIQMINKKFQETIFGSKSTAELDFFEINSL--FKNFKIDTEKTTLNKNVDFDLPPLLGENIEIHLQKAAETLNDPYMALLKGLDDWKIPQMPTMWSFQEGWTKYDTINNKFYKVSVPEENLLIFDVETLPKYTQRAVMAVAVGKSYWYSWTSKYLLDGICKDDSEICKDDLIPL-------YSNDDKSKPKCIVGHFVSFDRARIRDEYCIKGTGTRFIDTMSMQIAIRGMTSLQRSLKISFNNNNTENRIWKLYFSNSSKNGMNNSPEDIEESDKWLTEASLNSLVDVYQYYFPNCNLSSLKDKRETFIKGTIDDIVNDFQALMTYCATDVIMTAKIFQKLWTDYRVRFPHPASFTGMLEMGSLYLPVNSNLNTYINRASTTYESMIKKEKEILMELAQKS--LASKEKEYINDPWLWDLDW 1475
R++S S P PS+ +S + +LR+N ++IQM+++ E IFG + S+ + + + TT +V LP L G N++ H + A+ + PY+ L + ++P P W + EGWT+Y + V++PEE L+FDVE +AVA+ S WYSW S+ L++ S++ DLIPL S + + +VGH VSFDRA IR++Y I+G+ RF+DTMSM +AI G++S QRSL + + + S KN N P I D W+ +S N+L DV+ Y L+ K+ RE F+KG++ DI +FQ LM YCA DV T ++FQ+ + R PHP + GMLEMG YLPVN N Y+ A +TYE + ++ K+ LMELA + L S E+ Y DPWLWDL+W
Sbjct: 24 RWVSSSVLDPVPSDGQPQSQMPSSENGQLRLNPLHIQMLSRGLHEQIFGCGGDVPDEAAVQRSIEHLRKHGLWGQPTTPLPDVQLRLPRLFGGNLDQHFRLLAQKQSLPYLEAAASLSEAQLPPQPRKWVWAEGWTRYGP-EGEAEPVAIPEERALVFDVEVCLAEGTCPTLAVAISPSAWYSWCSRRLVEERYSWTSQLSPADLIPLGVSASASSSTQQDWQEQLVVGHNVSFDRAHIREQYLIQGSRMRFLDTMSMHMAISGLSSFQRSLWMGAKQGKHKTQHPTKRGQKSQKNA--NGPA-ISSWD-WMDISSANNLADVHNLYVGGPRLA--KEPRELFVKGSMRDIRENFQDLMEYCARDVWATFEVFQQQLPLFLERCPHPVTLAGMLEMGVSYLPVNQNWERYLTEAQSTYEELQREMKKSLMELANDACQLLSGER-YKEDPWLWDLEW 472 HSP 3 Score: 54.6842 bits (130), Expect = 6.279e-6 Identity = 22/59 (37.29%), Postives = 34/59 (57.63%), Query Frame = 3
Query: 1494 SFPKWFRVLVSK-NENSNTFNPDLITSQKSIAVKMLKLKWDGLPLHYDKKNKWGVLIPG 1667
P W+R L + ++ + T P L++ Q + K++ L WDG PLHY + WG L+PG
Sbjct: 549 GHPGWYRKLCPRLDDPAWTPGPSLLSLQMRVTPKLMALTWDGFPLHYSDSHGWGYLVPG 607
BLAST of DNA polymerase subunit gamma vs. UniProt/SwissProt
Match: sp|P54098|DPOG1_HUMAN (DNA polymerase subunit gamma-1 OS=Homo sapiens OX=9606 GN=POLG PE=1 SV=1) HSP 1 Score: 429.869 bits (1104), Expect = 2.438e-129 Identity = 230/489 (47.03%), Postives = 288/489 (58.90%), Query Frame = 3
Query: 2118 IPFVWFLPLPHEKGEGNTVGSPFSKSFLNYMQSGRLTSHAANNLLEIMIEGKKSGVFWRNYQNRVQSQFMV---RTS------------KENNESAIIPQVIVAGTVTRRSVERLWLTATNSTNDRVGSELKAMVQTPTNWVMVGADVDSQEQWIAAVLGDS-VTGIHGGTPFGWMVLQGSKVDGTDLHSKTSKMIGISRNAAKVLNYSRMYGAGIKSSTDTLLKYNPELKPQEAFNKIKDLMKQTKG---------------------KRSQGKWVD------------------------------GIESEVFSKLEEIAKSDEPSTPVLNARLSQALEKRVVNEKFMTSKCNWVVQSSGVDYLHCLLTFTKHLIQLYNVNARLCICIHDEIRYLCEEKDKYRLALILQIANLYTRSVFSMKLNLFDLPQSIAFFSEIDIDYCLRKSPTDDCITPSNQNGLLNNYNIQKGESLNIYQILDKTGGRLD 3383
IP WF LPH+ G VGSPF+K FL M+ G L + +E K FWRN R+ SQ +V R++ +E AI+PQV+ AGT+TRR+VE WLTA+N+ DRVGSELKAMVQ P + +VGADVDSQE WIAAVLGD+ G+HG T FGWM LQG K GTDLHSKT+ +GISR AK+ NY R+YGAG + L+++N L QEA K + + TKG R++G W+ G ESE+F+KLE IA SD P TPVL +S+ALE V E+FMTS+ NWVVQSS VDYLH +L K L + + ++ R CI IHDE+RYL E+D+YR AL LQI NL TR +F+ KL L DLPQS+AFFS +DID CLRK T DC TPSN G+ Y I +GE+L+IYQI++ T G L+
Sbjct: 744 IPGCWFFKLPHKDGNSCNVGSPFAKDFLPKMEDGTLQAGPGGASGPRALEINKMISFWRNAHKRISSQMVVWLPRSALPRAVIRHPDYDEEGLYGAILPQVVTAGTITRRAVEPTWLTASNARPDRVGSELKAMVQAPPGYTLVGADVDSQELWIAAVLGDAHFAGMHGCTAFGWMTLQGRKSRGTDLHSKTATTVGISREHAKIFNYGRIYGAGQPFAERLLMQFNHRLTQQEAAEKAQQMYAATKGLRWYRLSDEGEWLVRELNLPVDRTEGGWISLQDLRKVQRETARKSQWKKWEVVAERAWKGGTESEMFNKLESIATSDIPRTPVLGCCISRALEPSAVQEEFMTSRVNWVVQSSAVDYLHLMLVAMKWLFEEFAIDGRFCISIHDEVRYLVREEDRYRAALALQITNLLTRCMFAYKLGLNDLPQSVAFFSAVDIDRCLRKEVTMDCKTPSNPTGMERRYGIPQGEALDIYQIIELTKGSLE 1232 HSP 2 Score: 275.404 bits (703), Expect = 6.931e-75 Identity = 160/435 (36.78%), Postives = 232/435 (53.33%), Query Frame = 3
Query: 204 NSSDDKLRINMMNIQMINKKFQETIFGSKS--TAELDFFEINSLFKNFKIDTEKTTLNKNVDFDLPPLLGENIEIHLQKAAETLNDPYMALLKGLDDWKIPQMPTMWSFQEGWTKYDTINNKFYKVSVPEENLLIFDVETLPKYTQRAVMAVAVGKSYWYSWTSKYLLDGICKDDSEICKDDLIPLYSNDDKSKP-------KCIVGHFVSFDRARIRDEYCIKGTGTRFIDTMSMQIAIRGMTSLQRSLKISFNNNNTENRIWKLYFSNSSKNGMNNSPEDIEESDKWLTEASLNSLVDVYQYYFPNCNLSSLKDKRETFIKGTIDDIVNDFQALMTYCATDVIMTAKIFQKLWTDYRVRFPHPASFTGMLEMGSLYLPVNSNLNTYINRASTTYESMIKKEKEILMELAQKS--LASKEKEYINDPWLWDLDW 1475
+S +LR N ++IQM+++ E IFG E + + + +V+ LPPL G+N++ H + A+ + PY+ L ++P P W++ EGWT+Y + V++PEE L+FDVE +AVA+ S WYSW S+ L++ S++ DLIPL S P + +VGH VSFDRA IR++Y I+G+ RF+DTMSM +AI G++S QRSL I+ + + S + I D WL +S+NSL +V++ Y L K+ RE F+KGT+ DI +FQ LM YCA DV T ++FQ+ + R PHP + GMLEMG YLPVN N Y+ A TYE + ++ K+ LM+LA + L S E+ Y DPWLWDL+W
Sbjct: 63 SSEGGQLRHNPLDIQMLSRGLHEQIFGQGGEMPGEAAVRRSVEHLQKHGLWGQPAVPLPDVELRLPPLYGDNLDQHFRLLAQKQSLPYLEAANLLLQAQLPPKPPAWAWAEGWTRYGP-EGEAVPVAIPEERALVFDVEVCLAEGTCPTLAVAISPSAWYSWCSQRLVEERYSWTSQLSPADLIPLEVPTGASSPTQRDWQEQLVVGHNVSFDRAHIREQYLIQGSRMRFLDTMSMHMAISGLSSFQRSLWIAAKQGKHKVQPPTKQGQKSQRKARRGP--AISSWD-WLDISSVNSLAEVHRLYVGGPPLE--KEPRELFVKGTMKDIRENFQDLMQYCAQDVWATHEVFQQQLPLFLERCPHPVTLAGMLEMGVSYLPVNQNWERYLAEAQGTYEELQREMKKSLMDLANDACQLLSGER-YKEDPWLWDLEW 490 HSP 3 Score: 56.6102 bits (135), Expect = 1.433e-6 Identity = 22/59 (37.29%), Postives = 36/59 (61.02%), Query Frame = 3
Query: 1494 SFPKWFRVLVSK-NENSNTFNPDLITSQKSIAVKMLKLKWDGLPLHYDKKNKWGVLIPG 1667
P W+R L + ++ + T P L++ Q + K++ L WDG PLHY +++ WG L+PG
Sbjct: 568 GHPGWYRKLCPRLDDPAWTPGPSLLSLQMRVTPKLMALTWDGFPLHYSERHGWGYLVPG 626
BLAST of DNA polymerase subunit gamma vs. TrEMBL
Match: A0A068WP15 (DNA polymerase subunit gamma OS=Echinococcus granulosus OX=6210 GN=EgrG_000243450 PE=4 SV=1) HSP 1 Score: 841.647 bits (2173), Expect = 0.000e+0 Identity = 472/1155 (40.87%), Postives = 682/1155 (59.05%), Query Frame = 3
Query: 219 KLRINMMNIQMINKKFQETIFGSK---------STAELDFFEINSLFKNFKIDTEKTTLNKNVDFDLPPLLGENIEIHLQKAAETLNDPYMALLKGLDDWKIPQMPTMWSFQEGWTKYDTINNKFYKVSVPEENLLIFDVETLPKYTQRAVMAVAVGKSYWYSWTSKYLLDGICKDDSEICKDDLIPLYSNDDK-SKPKCIVGHFVSFDRARIRDEYCIKGTGTRFIDTMSMQIAIRGMTSLQRSLKISFNNNNTENRIWKLYFSNSSKNGMNNSPEDIEESDKWLTEASLNSLVDVYQYYFPNCNLSSLKDK--RETFIKGTIDDIVNDFQALMTYCATDVIMTAKIFQKLWTDYRVRFPHPASFTGMLEMGSLYLPVNSNLNTYINRASTTYESMIKKEKEILMELAQKSLA---SKEKEYINDPWLWDLDWSTTKK-----------SSFPKWFRVLVSKNENSN-TFNPDLITSQKSIAVKMLKLKWDGLPLHYDKKNKWGVLIPGCYL-----PVWYDEKFMDISNK-LIWPIIPVERISPSYIDYFQFPLQKYVQFWVPLFVSRLEAF--RDFLLSLGNSDLTKYNVFVEYMMAIVEPINFTPENLTKVNSLLCEIKEITLRNSKGYYNSNEEGPLSLYNF-QMNDFSSLF------------------AKTKCLL-----TENPIIPFVWFLPLPHEKGEGNTVGSPFSKSFLNYMQSGRLTS---------HAANNLLEIMIEGKKSGVFWRNYQNRVQSQF-----------MVRTSKENNE-------SAIIPQVIVAGTVTRRSVERLWLTATNSTNDRVGSELKAMVQTPTNWVMVGADVDSQEQWIAAVLGDSVTGIHGGTPFGWMVLQGSKVDGTDLHSKTSKMIGISRNAAKVLNYSRMYGAGIKSSTDTLLKYNPELKPQEAFNKIKDLMKQTKGKR---SQGK-----------WVDGIESEVFSKLEEIAKSDEPSTPVLNARLSQALEKRVVNEKFMTSKCNWVVQSSGVDYLHCLLTFTKHLIQLYNVNARLCICIHDEIRYLCEEKDKYRLALILQIANLYTRSVFSMKLNLFDLPQSIAFFSEIDIDYCLRKSPTDDCITPSNQNGLLNNYNIQKGESLNIYQILDKTGGRLD 3383
+L N +NIQMI+++ Q+ +F + + +L IN+ ID + + VD LPP LG NI+ H + A L+ PY+ L+ L +P++P W GWT Y + +++VS P +++L+FD E L V+AVA ++WY W S LL + + + + DDLI YS+ S PKCI+GHFVS+DRARI +EY I+ TG RF+DTMS+ I + G+TS QR+LK++ + + N++WK + + + +N PE ++ W+ +ASLNSL+DV+++Y C ++K R F KG+ D++++FQAL TYCA DV MT + F+ LW Y+ RFPHPA+F G+LEMGS+YLP+NS+ + RA+ +Y+ + K+K +L LA+ +L +K Y DPWLWDLDWS KK ++ PKW+R L+ K N P LIT+Q IA K+L+L W GLPLHYD+ KWG LIPG P +Y++K D S + I P+ V ++S + D FP ++Y+++W RL R + N D + ++ ++ + VE P +L VN L+ +K+I+ + S P N ++ +LF ++ K L T NP IP WF PLP+E G G VGSP SK F ++ SGRL S H+A+ +L I FW++Y RV SQ V+T+ N + AI+PQVI AGT++RR+VE LWLTA+N+ +R+GSE+KA+VQ P + +VGADVDSQE WIA+++GDSV G GGTP+GWM L+GSK GTDLH+KT+ +IGI RN AK+LNY+R+YG+G++ + L K+ L+P+EA K + LM+ TKG R GK W DG ES VF+ LE IA+S EP TPVL A++++ L VV + F+ S+ NWVVQSS VDYLHCLL F LI+ Y++ ARLCI IHDE+RYLC+++ ++AL LQI+NL TR++F+ +L + DLP+S+A+FS +++D CLRK P++DC TPSN +GL YNI KG S I +I+++TGG ++
Sbjct: 26 ELVFNEVNIQMIDRRLQQLLFAKRIYSYELSKEACEKLRSHGINA------IDRREGETSHYVD--LPPFLGSNIKEHFELIASDLSKPYLQLIGRLS--LLPEIPKNWKLLSGWTAY--TKDSYFRVSCPPDDILVFDTEVLVNEGHAPVIAVAASPNFWYLWVSPRLLSSM-RSTNSVTIDDLIRFYSDGSALSSPKCIIGHFVSYDRARIFEEYLIEPTGLRFLDTMSLHICVSGLTSTQRNLKLASDKHLYNNKLWKDFVAEHNAKRGSNDPESLD----WIKDASLNSLLDVFKFY---CQKEPYQNKELRAVFEKGSRGDVIDNFQALATYCANDVKMTFETFRNLWKLYQERFPHPATFYGLLEMGSMYLPINSSWIDFQERANQSYDDLNTKQKVLLQRLAEDALQKHNGSDKSYEKDPWLWDLDWSKPKKPANKSESAQILANLPKWYRELIPKPIKDNYKSGPALITAQMKIAPKLLRLCWKGLPLHYDQILKWGTLIPGRVPKPVGDPRYYEQKQSDESTRSQILPVFKVTKMSATGPDELIFPYREYLKYWTKEMEERLCGVNSRRAFETRANPD-ARDDLLLDELRRSVE---VMPLDLDTVNHLVSSLKKISDNDRGEQVKSKNSLPPVYENLGELQAKGALFWGNKDRYETDHSVKWISASRRKKLRRSATDTINPEIPTCWFCPLPNEAGTGLPVGSPLSKPFQVHIASGRLYSSPTAGGGEDHSADQILRDRIRAS----FWQSYSKRVMSQMYVFLETNLLPPTVQTALRNGKVPFGRRYGAILPQVIAAGTISRRAVEPLWLTASNAERERLGSEIKALVQAPPGFCLVGADVDSQEMWIASLIGDSVVGFQGGTPYGWMTLEGSKAKGTDLHTKTANLIGIKRNEAKILNYARLYGSGLEFTKHLLSKFQSNLRPEEASLKAEKLMRATKGHRVPVHMGKGCKEEAETRYIWKDGTESCVFNALEAIARSPEPRTPVLGAQITKTLTPTVVKDDFLPSRINWVVQSSAVDYLHCLLVFMAWLIKKYSLRARLCISIHDEVRYLCDQRCADQMALALQISNLLTRALFAFQLGMHDLPESVAYFSSVEVDTCLRKDPSNDCKTPSNPDGLEITYNIPKGRSFTITEIIERTGGAME 1152
BLAST of DNA polymerase subunit gamma vs. TrEMBL
Match: A0A087W245 (POLAc domain-containing protein OS=Echinococcus multilocularis OX=6211 GN=EmuJ_000243450 PE=4 SV=1) HSP 1 Score: 838.951 bits (2166), Expect = 0.000e+0 Identity = 469/1163 (40.33%), Postives = 681/1163 (58.56%), Query Frame = 3
Query: 180 FGRLLNTA---NSSDDKLRINMMNIQMINKKFQETIFGSKSTAELDFFEINSLFKNFKIDTEKTTLNKNVDF-DLPPLLGENIEIHLQKAAETLNDPYMALLKGLDDWKIPQMPTMWSFQEGWTKYDTINNKFYKVSVPEENLLIFDVETLPKYTQRAVMAVAVGKSYWYSWTSKYLLDGICKDDSEICKDDLIPLYSNDDK-SKPKCIVGHFVSFDRARIRDEYCIKGTGTRFIDTMSMQIAIRGMTSLQRSLKISFNNNNTENRIWKLYFSNSSKNGMNNSPEDIEESDKWLTEASLNSLVDVYQYYFPNCNLSSLKDK--RETFIKGTIDDIVNDFQALMTYCATDVIMTAKIFQKLWTDYRVRFPHPASFTGMLEMGSLYLPVNSNLNTYINRASTTYESMIKKEKEILMELAQKSLA---SKEKEYINDPWLWDLDWSTTKK-----------SSFPKWFRVLVSKNENSN-TFNPDLITSQKSIAVKMLKLKWDGLPLHYDKKNKWGVLIPGCYL-----PVWYDEKFMDISNK-LIWPIIPVERISPSYIDYFQFPLQKYVQFWVPLFVSRLEA--FRDFLLSLGNSDLTKYNVFVEYMMAIVEPINFTPENLTKVNSLLCEIKEITLRNSKGYYNSNEEGPLSLYNF-QMNDFSSLF------------------AKTKCLL-----TENPIIPFVWFLPLPHEKGEGNTVGSPFSKSFLNYMQSGRLTS---------HAANNLLEIMIEGKKSGVFWRNYQNRVQSQF-----------MVRTSKENNE-------SAIIPQVIVAGTVTRRSVERLWLTATNSTNDRVGSELKAMVQTPTNWVMVGADVDSQEQWIAAVLGDSVTGIHGGTPFGWMVLQGSKVDGTDLHSKTSKMIGISRNAAKVLNYSRMYGAGIKSSTDTLLKYNPELKPQEAFNKIKDLMKQTKGKR---SQGK-----------WVDGIESEVFSKLEEIAKSDEPSTPVLNARLSQALEKRVVNEKFMTSKCNWVVQSSGVDYLHCLLTFTKHLIQLYNVNARLCICIHDEIRYLCEEKDKYRLALILQIANLYTRSVFSMKLNLFDLPQSIAFFSEIDIDYCLRKSPTDDCITPSNQNGLLNNYNIQKGESLNIYQILDKTGGRLD 3383
F R L +A + +L N +NIQMI+++ Q+ +F + + E +N I+ + + DLPP LG NI+ H + A L+ PY+ L++ L +P++P W GWT Y + +++VS P + +L+FD E L +AVA ++WY W S LL + + + + DDLI YS+ S PKCI+GHFVS+DRARI +EY ++ TG RF+DTMS+ I + G+TS QR+LK++ + + N++WK + + + +N PE ++ W+ ASLNSL+DV+++Y C ++K R F KG+ D++++FQAL TYCA DV MT + F+ LW Y+ RFPHPA+F G+LEMGS+YLP+NS+ + RA+ +Y+ + K+K +L LA+ +L +K Y DPWLWDLDWS KK ++ PKW+R L+ K N P LIT+Q IA K+L+L W GLPLHYD+ KWG LIPG P +Y++ D S + I P+ V ++S + +D FP ++Y+ +W RL R + N D + ++ ++ + VE P +L VN L+ +K+I+ + S P N ++ +LF ++ K L T NP IP WF PLP+E G G VGSP SK F ++ SGRL S H+A+ +L I FW++Y RV SQ V+T+ N + AI+PQVI AGT++RR+VE LWLTA+N+ +R+GSE+KA+VQ P + +VGADVDSQE WIA+++GDSV G GGTP+GWM L+GSK GTDLH+KT+ +IGI RN AK+LNY+R+YG+G++ + L K+ L+P+EA K + LM+ TKG R GK W DG ES VF+ LE IA+S EP TPVL A++++ L +V + F+ S+ NWVVQSS VDYLHCLL F LI+ Y + ARLCI IHDE+RYLC+++ ++AL LQI+NL TR++F+ +L + DLP+S+A+FS +++D CLRK P++DC TPSN +GL YNI KG S I +I+++TGG ++
Sbjct: 10 FVRQLASAKVIRCNKQELVFNEVNIQMIDRRLQQLLFAKRIYSYELSKEACEKLRNHGINAIDRREGETSHYVDLPPFLGSNIKEHFELIASDLSKPYLQLIRRLS--LLPEIPKNWKLLSGWTAY--TKDSYFRVSCPPDEILVFDTEVLVNEGHAPTIAVAASPNFWYLWVSPRLLSSM-RSTNSVTIDDLIRFYSDGSPLSSPKCIIGHFVSYDRARIFEEYLVEPTGLRFLDTMSLHICVSGLTSTQRNLKLASDKHLYNNKLWKDFVAEHNAKRGSNDPESLD----WIKGASLNSLLDVFKFY---CQKEPYQNKELRAVFEKGSRGDVIDNFQALATYCANDVKMTFETFRNLWKLYQERFPHPATFYGLLEMGSMYLPINSSWIDFQERANQSYDDLNTKQKVLLQRLAEDALQKHNGSDKSYEKDPWLWDLDWSKPKKPANKSESAQVLANLPKWYRELIPKPIKDNYKSGPSLITAQMKIAPKLLRLCWKGLPLHYDQILKWGTLIPGRVPKPIGDPRYYEQTQSDESPRSQILPVFKVTKMSATGLDELIFPYREYLHYWTKEMEERLCGVNLRRAFETRANPD-ARDDLLLDELCRSVE---VMPLDLDTVNRLVSSLKKISDNDRGEQVKSKNSLPPVHENLGELQAKGALFWGNKDRYETDHSVKWIPTSRRKKLRRSATDTINPEIPTCWFCPLPNEAGTGLPVGSPLSKPFQVHIASGRLYSSPTAGGGEDHSADQILRDRIRAS----FWQSYSKRVMSQMYVFLETNLLPPTVQTALRNGKVPFGRRYGAILPQVIAAGTISRRAVEPLWLTASNAERERLGSEIKALVQAPPGFCLVGADVDSQEMWIASLIGDSVVGFQGGTPYGWMTLEGSKAKGTDLHTKTANLIGIKRNEAKILNYARLYGSGLEFTKHLLSKFQSNLRPEEASLKAEKLMRATKGHRVPVHMGKGCKEEAETRYIWKDGTESCVFNALEAIARSPEPRTPVLGAQITKTLTPTIVKDDFLPSRINWVVQSSAVDYLHCLLVFMAWLIKKYRLRARLCISIHDEVRYLCDQRCADQMALALQISNLLTRALFAFQLGMHDLPESVAYFSSVEVDTCLRKDPSNDCKTPSNPDGLEITYNIPKGRSFTITEIIERTGGAME 1152
BLAST of DNA polymerase subunit gamma vs. TrEMBL
Match: A0A158QIB6 (POLAc domain-containing protein OS=Rodentolepis nana OX=102285 GN=HNAJ_LOCUS9091 PE=4 SV=1) HSP 1 Score: 814.298 bits (2102), Expect = 0.000e+0 Identity = 461/1108 (41.61%), Postives = 650/1108 (58.66%), Query Frame = 3
Query: 354 EKTTLNKNVDFDLPPLLGENIEIHLQKAAETLNDPYMALLKGLDDWKIPQMPTMWSFQEGWTKYDTINNKFYKVSVPEENLLIFDVETLPKYTQRAVMAVAVGKSYWYSWTSKYLLDGICKDDSEICKDDLIPLYS-NDDKSKPKCIVGHFVSFDRARIRDEYCIKGTGTRFIDTMSMQIAIRGMTSLQRSLKISFNNNNTENRIWKLYFSN-SSKNGMNNSPEDIEESDKWLTEASLNSLVDVYQYYFPNCNLS--SLKDKRETFIKGTIDDIVNDFQALMTYCATDVIMTAKIFQKLWTDYRVRFPHPASFTGMLEMGSLYLPVNSNLNTYINRASTTYESMIKKEKEILMELAQKSLA---SKEKEYINDPWLWDLDWSTTKK-----------SSFPKWFRVLVSKN-ENSNTFNPDLITSQKSIAVKMLKLKWDGLPLHYDKKNKWGVLIPGCYL-----PVWYDEKFMDIS-NKLIWPIIPVERISPSYIDYFQFPLQKYVQFWVPL-------------FVSRLEA-FRDFLLSLGNSDLTKYNVFVEYMMAIVEPINFTPENLTKVNSLLCEIKEITLRNSKGYYNSNEEGPLSLYNF-QMNDFSSLFAKTK-----------------------CLLTENPIIPFVWFLPLPHEKGEGNTVGSPFSKSFLNYMQSGRLTSHA------ANNLLEIMIEGKKSGVFWRNYQNRVQSQFMV----------------RTSKENN---ESAIIPQVIVAGTVTRRSVERLWLTATNSTNDRVGSELKAMVQTPTNWVMVGADVDSQEQWIAAVLGDSVTGIHGGTPFGWMVLQGSKVDGTDLHSKTSKMIGISRNAAKVLNYSRMYGAGIKSSTDTLLKYNPELKPQEAFNKIKDLMKQTKGKR---------SQGK--WVDGIESEVFSKLEEIAKSDEPSTPVLNARLSQALEKRVVNEKFMTSKCNWVVQSSGVDYLHCLLTFTKHLIQLYNVNARLCICIHDEIRYLCEEKDKYRLALILQIANLYTRSVFSMKLNLFDLPQSIAFFSEIDIDYCLRKSPTDDCITPSNQNGLLNNYNIQKGESLNIYQILDKTGGRL 3380
E+ + ++ DLPPL G NI+ H A L+ PY+ + L +P+MPT W GWT Y +N F+KV VP E++ +FD E L + V+ VA + WY W S L+ K + DL+P YS N S PKC++GHFVS+DRARI +EY + +G RF+DTMS+ I + G+TS QR+LK++ + + N++WK + + +S+ G ++ ES W+ +ASLNSL+DV++ Y C KD R TF KGT D++ DFQ L++YCA DV+MT ++FQ LW Y RFPHPA+F G+LEMGS+YLP+N++ + RA+ TY+ + +K +L +LA+ +L +K Y DPWLWDLDWS K+ S+ PKW+R L+ K ++ P LIT+Q IA K+L+L W GLPLHYD KWG LIPG P +Y +K +D S + I P V + + + + FP ++++ +W + F SR+E RD LL L + VE M P +L V L+ IKEIT SK + L N ++ +LF + + T NP+IP WF PLP+E G G VGSP SK F ++ +GRL S + +N + ++ + FW++Y RV +Q V S N AI+PQVI AGT++RR+VE LWLTA+N+ +R+GSE+KAMVQ P + +VGADVDSQE WIA+++GDSV G GGTP+GWM L+GSK GTDLH+KT+ +IGI RN AKVLNY+R+YG+G++ + L K+ L+P+EA K + LM+ TKG+R S+ K W DG ES VF+ LE IA+S EP TPVL+A++++AL + V F+ S+ NWVVQSS VDYLHC+L F LI+ YN+ ARLCI IHDE+RYLC+++ ++AL LQI+NL TR++F+ +L + DLP+S+A+FS ++ID CLRK P +DC TPSN +GL Y I KGESL + +I+++TGG +
Sbjct: 827 ERRQVEESQYIDLPPLYGTNIKQHFDSIAADLSKPYLDSIGQLK--SLPEMPTKWQMIPGWTAY--VNGSFFKVDVPLEDVFVFDTEVLVTESCAPVIGVAASSNAWYLWVSPRLI-STSKPMKTVSMYDLVPFYSSNGQYSNPKCVIGHFVSYDRARIMEEYLTEPSGIRFVDTMSLHICVSGLTSTQRNLKLASDKHLYNNKLWKDFVAEYNSRKGSGDA-----ESLDWIKDASLNSLLDVFKLY---CQKEPYQTKDLRSTFEKGTRRDVIGDFQNLVSYCAYDVLMTFEVFQNLWKLYIERFPHPATFYGLLEMGSMYLPINTSWIDFQERANKTYDELNNGQKTLLQKLAEDALNRHNGPDKSYQMDPWLWDLDWSKPKRPANKSESALVLSNLPKWYRDLIPKPMKDHYKTGPSLITAQMKIAPKLLRLCWKGLPLHYDNTLKWGTLIPGRVPKPVGDPYYYVQKVVDDSPRRQIRPSFMVTKTTAAGNEELVFPYREHLLYWEKVIEKLLWGLDPKSAFESRVEPDPRDDLL------LDELRRSVEVM----------PLDLDTVKRLIDSIKEITGDQSKEQVKVVKPSQLIYENLGELQAKGALFWQNRDRYDSDNRSKWIPPSRKKKIRRTATDTVNPVIPTCWFCPLPNEAGTGLPVGSPLSKPFQVHIAAGRLHSASWDAEGGPDNTADQILRDRIRASFWQSYSKRVCAQMYVFLENNMLPPSVQVALDEVSSNGNLRRYGAIVPQVIAAGTISRRAVEPLWLTASNAEAERLGSEIKAMVQAPPGFCLVGADVDSQEMWIASLIGDSVIGFQGGTPYGWMTLEGSKSKGTDLHTKTANLIGIKRNEAKVLNYARLYGSGLEFTKHLLSKFQSNLRPEEASIKAEKLMRATKGQRVPIQSPESNSEMKYMWKDGTESYVFNALEAIARSPEPRTPVLSAQITRALTPQAVKGDFLPSRINWVVQSSAVDYLHCILVFMAWLIRKYNLRARLCISIHDEVRYLCDQRCADQVALALQISNLLTRALFAFQLGMHDLPESVAYFSSVEIDTCLRKDPLNDCKTPSNPDGLEITYGIPKGESLTVSEIIERTGGSM 1905
BLAST of DNA polymerase subunit gamma vs. TrEMBL
Match: A0A5K3EXL1 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1) HSP 1 Score: 806.979 bits (2083), Expect = 0.000e+0 Identity = 463/1147 (40.37%), Postives = 656/1147 (57.19%), Query Frame = 3
Query: 231 NMMNIQMINKKFQETIFGSKSTAELDFFEINSLFKNFKIDT-EKTTLNKNVDFDLPPLLGENIEIHLQKAAETLNDPYMALLKGLDDWKIPQMPTMWSFQEGWTKYDTINNKFYKVSVPEENLLIFDVETLPKYTQRAVMAVAVGKSYWYSWTSKYLLDGICKDDSEICKDDLIPLYSNDDK-SKPKCIVGHFVSFDRARIRDEYCIKGTGTRFIDTMSMQIAIRGMTSLQRSLKISFNNNNTENRIWKLYFS--NSSKNGMNNSPEDIEESDKWLTEASLNSLVDVYQYYFPNCNLSSLKDK--RETFIKGTIDDIVNDFQALMTYCATDVIMTAKIFQKLWTDYRVRFPHPASFTGMLEMGSLYLPVNSNLNTYINRASTTYESMIKKEKEILMELAQKSLA---SKEKEYINDPWLWDLDWSTTKK-----------SSFPKWFRVLVSKN-ENSNTFNPDLITSQKSIAVKMLKLKWDGLPLHYDKKNKWGVLIPGCYLPVWYDEKFMDISNKL-----------------IWPIIPVERISPSYIDYFQFPLQKYVQFWVPLFVSRLEAFRDFLLSLGNSDLTKYNVFVEYMMAIVEPINFTPENLTKVNSLLCEIKEITLRNSKGYYNSNEEGPLSLYNF--QMNDFSSLFAKTK-------CLL-------------TENPIIPFVWFLPLPHEKGEGNTVGSPFSKSFLNYMQSGRLTS-----HAANNLLEIMIEGKKSGVFWRNYQNRVQSQFMV----------RTSKENNESA--------IIPQVIVAGTVTRRSVERLWLTATNSTNDRVGSELKAMVQTPTNWVMVGADVDSQEQWIAAVLGDSVTGIHGGTPFGWMVLQGSKVDGTDLHSKTSKMIGISRNAAKVLNYSRMYGAGIKSSTDTLLKYNPELKPQEAFNKIKDLMKQTKGKR--------SQGK------WVDGIESEVFSKLEEIAKSDEPSTPVLNARLSQALEKRVVNEKFMTSKCNWVVQSSGVDYLHCLLTFTKHLIQLYNVNARLCICIHDEIRYLCEEKDKYRLALILQIANLYTRSVFSMKLNLFDLPQSIAFFSEIDIDYCLRKSPTDDCITPSNQNGLLNNYNIQKGESLNIYQILDKTGGRL 3380
N +NIQMI++K QE +F + + E I+ E++ + + +LPPLLG +++ H + A L+ PY ++ L K+P+ PT W F GWT Y N V P E L+FD E L K + ++AVA + WY W S L + + + + DLIPLYS S PKCIVGHFVS+DRARI +EY TG RF+DTMS+ I + G+TS QR +K++ + + N+++K + + N+ + N S D+E S +W+ EASLNSLV+VY+ Y C +DK R F KG+ D++ +FQ L+TYCA DV MT IFQ LW + RFPHP +F G+LEMGS+YLPVN + + RA+ Y + K+K +L +LA+ +L +K Y DPWLWDLDWS KK +S PKW+R L+ K ++ P L+T+Q IA K+L+L W+GLPLH+D+ KWG LIPG D +F ++ L I P I V + + + QFP ++Y+Q+W RL + D T + F+ + + + P + ++ L+ K+++ K + E+ L +Y + ++ +LF + K C + T NP I WF PLP+E G+G VGSP SK F ++ SGRL S N + ++ + FW++Y RV SQ V S N E+A I+PQVI AGT++RR+VE LWLTA+N+ +R+GSE+KAMVQ P + +VGADVDSQE WIA+++GDS G GGTP+GWM L+GSK GTDLH+KT+ +IGI RN AKVLNY+R+YG+G++ + L K+ ++P+EA K + LM+ TKG R S+GK W G ES VF+ LE IA+S EP TPVL A++++AL + V + F+ S+ NWVVQSS VDYLHCLL LI+ +N+ ARLCI IHDE+RYLC ++ +AL LQI+NL TRS F+ +L + DLP+S A+FS +++D CLRK P +DC TPSN +GL Y I KG+S I +I+++TGG L
Sbjct: 30 NEVNIQMIDRKLQEVLFSKRIPSYTVSKEACDKLSEHGINAYERSGGDAAMYINLPPLLGPDVKHHFEGIASELSKPYFNCIRSLS--KLPKPPTHWKFIPGWTSY--ANGTAISVDCPSEEGLVFDTEVLVKESNAPIIAVAASVNGWYLWVSPRLFEPPVEPTNMVTLADLIPLYSPGTSLSSPKCIVGHFVSYDRARITEEYLTDPTGLRFLDTMSLHICVSGLTSTQRHIKMASDKHLYNNKLFKDFVAELNAKRGSTNQS--DVE-SLEWIKEASLNSLVEVYKLY---CKKDPPQDKSLRVIFEKGSRKDVIKNFQKLVTYCALDVHMTFDIFQCLWKLFTERFPHPLTFYGLLEMGSMYLPVNRSWVDFQERANQAYADLNTKQKTMLQKLAEDALKRHNGNDKSYERDPWLWDLDWSKPKKPASKSEDAQYIASLPKWYRELIPKPIKDHYKEGPTLVTAQMKIAPKLLRLCWNGLPLHFDQTLKWGTLIPGRVPKPVGDPQFYKQNSNLKENRSSHALSIQSPQSQILPSITVVKTAAAGPRLLQFPYREYLQYWEKEIEKRLFDLNSRVAFKNRVDPTPRDKFL--LDELRRSVEVMPLDFDVMHRLIASFKQVS-EECKVEQFATEKLTLPIYEYLGELQVKGALFWQNKHRYDTRRCGMVGRQKIHRRTTTDTINPEIATCWFCPLPNEGGQGLPVGSPLSKPFQVHIASGRLHSAQTSGEGENQAADQILRDRIRASFWQSYSKRVMSQMYVFLPTRLLPPTVQSSLNEEAAPRGQLYGAILPQVIAAGTISRRAVEPLWLTASNAEPERLGSEIKAMVQAPPGYCIVGADVDSQEMWIASLIGDSKVGFQGGTPYGWMTLEGSKAKGTDLHTKTANLIGIKRNEAKVLNYARLYGSGVEFTKHLLSKFQSNIRPEEASLKAEKLMRATKGYRVSVPSQNNSEGKVEYKSIWRGGTESHVFNALEAIARSPEPRTPVLGAQITRALTPKAVQDDFLPSRINWVVQSSAVDYLHCLLVSMAWLIKKFNLRARLCISIHDEVRYLCYKRCADEVALALQISNLLTRSFFAYQLGMHDLPESAAYFSSVEVDSCLRKDPLNDCKTPSNPDGLEATYKIPKGKSFTIAEIIERTGGVL 1163
BLAST of DNA polymerase subunit gamma vs. TrEMBL
Match: A0A5K4EUB4 (Putative DNA polymerase gamma OS=Schistosoma mansoni OX=6183 PE=4 SV=1) HSP 1 Score: 803.897 bits (2075), Expect = 0.000e+0 Identity = 471/1210 (38.93%), Postives = 664/1210 (54.88%), Query Frame = 3
Query: 198 TANSSDDKLRINMMNIQMINKKFQETIFG-SKSTAELDFFEINSLFKNFKIDTEKTTLNKN-VDFDLPPLLGENIEIHLQKAAETLNDPYMALLKGLDDWKIPQMPTMWSFQEGWTKYDTINNKFYKVSVPEENLLIFDVETLPKYTQRAVMAVAVGKSYWYSWTSKYLL---DGICKDDSEICKDDLIPLYSNDDKSKPKCIVGHFVSFDRARIRDEYCIKGTGTRFIDTMSMQIAIRGMTSLQRSLKISFNNNNTENRIWKLYFSNSSKN---GMNNSPEDIEESDKWLTEASLNSLVDVYQYYFPNCNLSSLKDK--RETFIKGTIDDIVNDFQALMTYCATDVIMTAKIFQKLWTDYRVRFPHPASFTGMLEMGSLYLPVNSNLNTYINRASTTYESMIKKEKEILMELAQKSLA--SKEKEYINDPWLWDLDWSTTKK----------SSFPKWFRVLVSKNENSN-TFNPDLITSQKSIAVKMLKLKWDGLPLHYDKKNKWGVLIPGCYL-----PVWYDEKFMDISN-----------------------KLIWPIIPVERISPSYIDYFQFPLQKYVQFWVPLFVSRLEAFRDFLLSLGNSDLTKYN--VFVEYMMAI----------------VEPINFTPENLTKVNSLLCEIK-------------------------------EITLRNSKGYYNSN--EEGPLSLYNFQMNDFSSLFAKTKCLLTENPIIPFVWFLPLPHEKGEGNTVGSPFSKSFLNYMQSGRLTSHAAN------------------NLLEIMIEGKKSGVFWRNYQNRVQSQFMVRTSKEN---------------NESAIIPQVIVAGTVTRRSVERLWLTATNSTNDRVGSELKAMVQTPTNWVMVGADVDSQEQWIAAVLGDSVTGIHGGTPFGWMVLQGSKVDGTDLHSKTSKMIGISRNAAKVLNYSRMYGAGIKSSTDTLLKYNPELKPQEAFNKIKDLMKQTKGKR--------------SQGKWVDGIESEVFSKLEEIAKSDEPSTPVLNARLSQALEKRVVNEKFMTSKCNWVVQSSGVDYLHCLLTFTKHLIQLYNVNARLCICIHDEIRYLCEEKDKYRLALILQIANLYTRSVFSMKLNLFDLPQSIAFFSEIDIDYCLRKSPTDDCITPSNQNGLLNNYNIQKGESLNIYQILDKTGGRL 3380
++N + N +NI MI++ Q+ +F K + FE+ F ID K+ + F +P L G N++ HL A+ L+ PYM LL+ P++P +W GWTKY+ +K Y V P E+ LIFD E L K MAVA+ WYSWTSK L D D + + LIP+Y + +K KC++GHFVS+DRARI +EY + GTG RF+DT+S+ +A+ G+TS QR LK S + + N+ W+ + + G S E + WL+E SLNSL D+Y+ Y C +DK R F GTI+D+ +FQ L YCA DV+MT +I Q LW ++ RFPHPA+F G+LEM S+YLP+N N + +A ++Y I ++K++LM+LA ++LA S +EY NDPWLWDLDWS K S PKW+R L+ K N P L+T+Q IA K+LKL W GLPLHYD+ KWGVLIPG P +Y E F + N I PIIPV + + + + FP Y+ +W+ RL A DF L+ S ++ + V Y I +E + E ++ S + I+ E+ + S + NSN ++ + N++ + A + T NP+IP WF LPHE G G VGSP S+SF +++ S RL S N L + ++ + FW++Y R++SQ + + N AI+PQVI GTV+RR+VE LWLTA+N+ +R+GSE+KAMVQ+P +V VGADVDSQE WIAA++GD+ G G TP+GWM LQG+K+DGTDLH+K +K +GI R+ +KVLNYSR+YG+GI+ ++ L K+ + P++A K K L + TKG+R S KW G ES VF++LE IA+S EP TP LNA+L++AL ++V + F+ S+ NWVVQSS VDYLHC+L + LI + + ARLCI IHDE+RY+C + Y++AL LQI+NL TR+ F +L + DLP+S+AFFS +++D C+RK DDC+TPSN +GL N Y + G+SL + ILDKTGG +
Sbjct: 24 SSNHPNQSPTYNEVNILMIDRNLQKALFNCQKYDYQKASFEVLQEFCRLGIDITSNRHYKDPLYFSIPDLSGSNVKEHLDSVAKELSHPYMKLLESFG--SPPELPKIWESSSGWTKYN--GDKTYSVEAPLEDALIFDTEVLVKEGHVPTMAVALTSDGWYSWTSKRLSVYDDNYSNDINAF--NSLIPIYGSKNKDISKCVIGHFVSYDRARILEEYLLDGTGLRFVDTLSLHVAVSGLTSTQRFLKTSADKHLFNNKTWQEFIGRKNDKQPLGGKPSTEALVMDLDWLSETSLNSLPDIYRLY---CKKEPPQDKQLRSIFESGTIEDVRTNFQELFNYCAVDVLMTYEIIQVLWPIFKERFPHPATFCGLLEMSSMYLPINDNWIKFQEKAESSYTENILRQKKLLMQLADQALAKYSNSQEYKNDPWLWDLDWSKPKVKCKTEVDEKVSRLPKWYRDLIPKPVKDNLDSGPALLTAQMRIAPKLLKLCWQGLPLHYDQVLKWGVLIPGRIPQPYGDPRYYIESFKNTENTECIDSNDAENFSTNSNVVCHYDSSIRPIIPVVKSTAAGDETLDFPYGAYLNYWLADVKRRLLA--DFQLNESTSSCDNFSDSLAVAYSHRIKPDIRDANLLDELKRSIEIMPLEKEERQRLASTISTIRKLGEQKRFQMDSKLQKIKNNNHNELIFEKVGELQAQGSAFWLNSNRFDQNSSNYSNYRRRN-----AVRYAVDTVNPVIPTCWFKHLPHESGTGLPVGSPLSRSFQSHIASHRLHSADFNPNDTISANTDTIKLKPVMGLADRLLHDRVHATFWQSYSKRIKSQMAIWLPHDQLPKNVLNDQSYNCKANYGAILPQVITCGTVSRRAVEPLWLTASNADENRLGSEIKAMVQSPPGYVFVGADVDSQEMWIAALIGDAGVGFQGSTPYGWMTLQGNKLDGTDLHTKIAKEMGIKRSESKVLNYSRLYGSGIEFASHLLAKFC-NITPEQASLKAKQLFQITKGRRTIVDSFPSDDGTSISTSKWQGGSESAVFNQLESIARSPEPRTPFLNAQLTRALNPKLVKDDFLPSRVNWVVQSSAVDYLHCMLVLMRWLINKFKIPARLCISIHDELRYICPKSHMYQVALALQISNLLTRTFFVYQLGMRDLPESVAFFSSVEVDTCIRKEAKDDCVTPSNSSGLQNGYGVSPGQSLTMQDILDKTGGSM 1216
BLAST of DNA polymerase subunit gamma vs. Ensembl Cavefish
Match: polg (DNA polymerase gamma, catalytic subunit [Source:NCBI gene;Acc:103040749]) HSP 1 Score: 484.182 bits (1245), Expect = 3.795e-151 Identity = 277/661 (41.91%), Postives = 372/661 (56.28%), Query Frame = 3
Query: 1494 SFPKWFRVLVSK--NENSNTFNP--DLITSQKSIAVKMLKLKWDGLPLHYDKKNKWGVLIPGCYLPVWYDEKFMDISNKLIWPIIPVERISPSYIDYFQFPLQKYVQFWVPLFVSRLEAFRDFLLSLGNSDLTKYNVFVEY-MMAIVEPINFTPENLTKVNSLLCEIKEITLRNSKGYYNSNEEGPLSLYNFQMNDFSSLFAKTKCLLTENPIIPFVWFLPLPHEKGEGNTVGSPFSKSFLNYMQSGRLTSHAANNLLEIMIEGKKSGVFWRNYQNRVQSQFMV--------RT-------SKENNESAIIPQVIVAGTVTRRSVERLWLTATNSTNDRVGSELKAMVQTPTNWVMVGADVDSQEQWIAAVLGDS-VTGIHGGTPFGWMVLQGSKVDGTDLHSKTSKMIGISRNAAKVLNYSRMYGAGIKSSTDTLLKYNPELKPQEAFNKIKDLMKQTKGKRS-----------QGKWVDGIESEVFSKLEEIAKSDEPSTPVLNARLSQALEKRVVNEKFMTSKCNWVVQSSGVDYLHCLLTFTKHLIQLYNVNARLCICIHDEIRYLCEEKDKYRLALILQIANLYTRSVFSMKLNLFDLPQSIAFFSEIDIDYCLRKSPTDDCITPSNQNGLLNNYNIQKGESLNIYQILDKTGGRL 3380
P W+R L ++ + ++P LIT Q + K++ L WDG PLHY K+ WG L+PG +D + P+ P I Y +Y + + PL + ++ D +L+ D + + E M+ +V P + + ++ + Y++ N GP + N IP VWF LPH+ G N VGSPFSK FL+ M+ G L S +E K FWRN Q R+ SQ +V RT +E AI+PQV+ AGTVTRR+VE WLTA+N+ DRVGSELKAMVQ P + +VGADVDSQE WIAAVLG+S G+HG T FGWM LQG K GTDLHS+T+ +GISR AKV NY R+YGAG + L+++N L EA +K K + TKG RS + W G ESE+F+KLE IA S++P+TPVL R+S+ALE V ++F+TS+ NWVVQSS VDYLH +L + L++ ++++ R CI IHDE+RYL + +D+YR AL LQI NL TR +F+ KL + DLPQS+AFFS +DID CLRK T DC TPSN GL + I +GE+L+IYQI++KT G L
Sbjct: 538 GHPGWYRKLCARMSEKEDEAWSPGASLITLQMRLTPKLMGLTWDGFPLHYTDKHGWGYLVPG-------HRDNLDTTEDSEGPVCPHRAIEAIYREYCEEKGKGK-----PLCLDNQQS-DDLMLT----DSSVWQTVEELSMLEVVSDDEAVPRTVRPKKAQRSSLELDAGESECPYHHGN--GPYNDVN----------------------IPGVWFFKLPHKDGNENNVGSPFSKDFLSKMEDGTLHSGRGETNATRALEINKMMSFWRNAQKRISSQMVVWLRKGELPRTVSRHEDYDEEGQYGAILPQVVTAGTVTRRAVEPTWLTASNARRDRVGSELKAMVQVPPGYHLVGADVDSQELWIAAVLGESHFAGMHGCTAFGWMTLQGKKSQGTDLHSRTANAVGISREHAKVFNYGRIYGAGQPFAERLLMQFNHRLSQPEAADKAKQMYALTKGLRSFRNKKRWDLVGRRVWAGGTESEMFNKLESIAHSEQPATPVLGCRISRALEPAAVKDEFITSRVNWVVQSSAVDYLHLMLVAMRWLLEEFDIDGRFCISIHDEVRYLVKSEDRYRAALALQITNLLTRCMFAYKLGMKDLPQSVAFFSAVDIDQCLRKEVTMDCATPSNPIGLEGRFGIPQGEALDIYQIIEKTKGSL 1157 HSP 2 Score: 282.722 bits (722), Expect = 1.311e-78 Identity = 166/476 (34.87%), Postives = 262/476 (55.04%), Query Frame = 3
Query: 135 LRFLSYSGYLPKPSNFGRLLNTANS------SDDKLRINMMNIQMINKKFQETIFGSKSTAELDFFEINSLFKNFKIDT---EKTTLNKNVDFDLPPLLGENIEIHLQKAAETLNDPYMALLKGLDDWKIPQMPTMWSFQEGWTKYDTINNKFYKVSVPEENLLIFDVETLPKYTQRAVMAVAVGKSYWYSWTSKYLLDGICKDDSEICKDDLIPLYSNDDKSKP-------KCIVGHFVSFDRARIRDEYCIKGTGTRFIDTMSMQIAIRGMTSLQRSLKISFNNNNTENRIWKLYFSNSSKNGMNNSPED-IEESDKWLTEASLNSLVDVYQYYFPNCNLSSLKDKRETFIKGTIDDIVNDFQALMTYCATDVIMTAKIFQKLWTDYRVRFPHPASFTGMLEMGSLYLPVNSNLNTYINRASTTYESMIKKEKEILMELAQKSLA-SKEKEYINDPWLWDLDWSTT--KKSSFP 1502
LR +S+ + P+ R TA + + + R N +NIQM+++ +E IF S S E +I+ ++ + + ++ L V+ LP + G++I+ H + A+ + PY+ L +PQMP W+++ GWT+Y ++ + KV+ PEEN ++FDVE + +AVAV + WYSW SK L++ S++ DLIPL + + S+P + ++GH VSFDRA I+++Y +KG+ RF+DTMS+ +AI G+T QRSL ++ + L + PE + S +W+ +S+N+L DV+ Y L K+ R+ F+KG+++D+ N+FQ LM YCATDV+ T ++F + + + R PHP +F GMLEMG YLPVN + YI A TYE + ++ K+ LM LA + ++ Y DPWLWDLDW KK P
Sbjct: 2 LRLVSHQPWRCSPAAVWRRRCTAAAEAKHQQNSKETRTNPLNIQMLSRNLREQIFRS-SVQEYADEDIDRSIRHLEKHSLWGKEAVLLPEVELKLPQMYGDDIDEHFRILAQKQSLPYLEAASQLQQAHLPQMPQKWAWEVGWTRYG-LDGQCKKVNFPEENAVVFDVEVCMAEGRCPTLAVAVSPTAWYSWCSKRLVEERYTWSSQLTLADLIPLETPSNSSRPPGGQWKERLVIGHNVSFDRAHIKEQYLLKGSKMRFLDTMSLHMAISGLTGFQRSLWMASRHGKRRG----LQEVKEHIKKLGRRPEGPMIGSWEWVNISSINNLTDVHALYVGGEPLK--KEPRDIFVKGSMNDVRNNFQELMQYCATDVLATHEVFTQQLSLFMERCPHPVTFAGMLEMGVSYLPVNESWGRYIEDAQDTYEELQREMKKSLMILADDACQLLQDDRYKEDPWLWDLDWDVQEFKKKKMP 469
BLAST of DNA polymerase subunit gamma vs. Ensembl Cavefish
Match: polg (DNA polymerase gamma, catalytic subunit [Source:NCBI gene;Acc:103040749]) HSP 1 Score: 467.233 bits (1201), Expect = 1.683e-144 Identity = 277/702 (39.46%), Postives = 374/702 (53.28%), Query Frame = 3
Query: 1494 SFPKWFRVLVSK--NENSNTFNP--DLITSQKSIAVKMLKLKWDGLPLHYDKKNKWGVLIPGCYLPVWYDEKFMDISNKLIWPIIPVERISPSYIDYFQFPLQKYVQFWVPLFVSRLEAFRDFLLSLGNSDLTKYNVFVEY-MMAIVEPINFTPENLTKVNSLLCEIKEITLRNSKGYYNSNEEGPLSLYNFQMNDFSSLFAKTKCLLTENPIIPFVWFLPLPHEKGEGNTVGSPFSKSFLNYMQSGRLTSHAANNLLEIMIEGKKSGVFWRNYQNRVQSQFMV--------RT-------SKENNESAIIPQVIVAGTVTRRSVERLWLTATNSTNDRVGSELKAMVQTPTNWVMVGADVDSQEQWIAAVLGDS-VTGIHGGTPFGWMVLQGSKVDGTDLHSKTSKMIGISRNAAKVLNYSRMYGAGIKSSTDTLLKYNPELKPQEAFNKIKDLMKQTKGKR-----SQGKWV-----------------------------------------------DGIESEVFSKLEEIAKSDEPSTPVLNARLSQALEKRVVNEKFMTSKCNWVVQSSGVDYLHCLLTFTKHLIQLYNVNARLCICIHDEIRYLCEEKDKYRLALILQIANLYTRSVFSMKLNLFDLPQSIAFFSEIDIDYCLRKSPTDDCITPSNQNGLLNNYNIQKGESLNIYQILDKTGGRL 3380
P W+R L ++ + ++P LIT Q + K++ L WDG PLHY K+ WG L+PG +D + P+ P I Y +Y + + PL + ++ D +L+ D + + E M+ +V P + + ++ + Y++ N GP + N IP VWF LPH+ G N VGSPFSK FL+ M+ G L S +E K FWRN Q R+ SQ +V RT +E AI+PQV+ AGTVTRR+VE WLTA+N+ DRVGSELKAMVQ P + +VGADVDSQE WIAAVLG+S G+HG T FGWM LQG K GTDLHS+T+ +GISR AKV NY R+YGAG + L+++N L EA +K K + TKG R +G+W+ G ESE+F+KLE IA S++P+TPVL R+S+ALE V ++F+TS+ NWVVQSS VDYLH +L + L++ ++++ R CI IHDE+RYL + +D+YR AL LQI NL TR +F+ KL + DLPQS+AFFS +DID CLRK T DC TPSN GL + I +GE+L+IYQI++KT G L
Sbjct: 538 GHPGWYRKLCARMSEKEDEAWSPGASLITLQMRLTPKLMGLTWDGFPLHYTDKHGWGYLVPG-------HRDNLDTTEDSEGPVCPHRAIEAIYREYCEEKGKGK-----PLCLDNQQS-DDLMLT----DSSVWQTVEELSMLEVVSDDEAVPRTVRPKKAQRSSLELDAGESECPYHHGN--GPYNDVN----------------------IPGVWFFKLPHKDGNENNVGSPFSKDFLSKMEDGTLHSGRGETNATRALEINKMMSFWRNAQKRISSQMVVWLRKGELPRTVSRHEDYDEEGQYGAILPQVVTAGTVTRRAVEPTWLTASNARRDRVGSELKAMVQVPPGYHLVGADVDSQELWIAAVLGESHFAGMHGCTAFGWMTLQGKKSQGTDLHSRTANAVGISREHAKVFNYGRIYGAGQPFAERLLMQFNHRLSQPEAADKAKQMYALTKGLRRYHLSEEGEWLVNELGVDVNWDEYGTVSREELRRISKLAGTSFRNKKRWDLVGRRVWAGGTESEMFNKLESIAHSEQPATPVLGCRISRALEPAAVKDEFITSRVNWVVQSSAVDYLHLMLVAMRWLLEEFDIDGRFCISIHDEVRYLVKSEDRYRAALALQITNLLTRCMFAYKLGMKDLPQSVAFFSAVDIDQCLRKEVTMDCATPSNPIGLEGRFGIPQGEALDIYQIIEKTKGSL 1198 HSP 2 Score: 282.337 bits (721), Expect = 2.591e-78 Identity = 166/476 (34.87%), Postives = 262/476 (55.04%), Query Frame = 3
Query: 135 LRFLSYSGYLPKPSNFGRLLNTANS------SDDKLRINMMNIQMINKKFQETIFGSKSTAELDFFEINSLFKNFKIDT---EKTTLNKNVDFDLPPLLGENIEIHLQKAAETLNDPYMALLKGLDDWKIPQMPTMWSFQEGWTKYDTINNKFYKVSVPEENLLIFDVETLPKYTQRAVMAVAVGKSYWYSWTSKYLLDGICKDDSEICKDDLIPLYSNDDKSKP-------KCIVGHFVSFDRARIRDEYCIKGTGTRFIDTMSMQIAIRGMTSLQRSLKISFNNNNTENRIWKLYFSNSSKNGMNNSPED-IEESDKWLTEASLNSLVDVYQYYFPNCNLSSLKDKRETFIKGTIDDIVNDFQALMTYCATDVIMTAKIFQKLWTDYRVRFPHPASFTGMLEMGSLYLPVNSNLNTYINRASTTYESMIKKEKEILMELAQKSLA-SKEKEYINDPWLWDLDWSTT--KKSSFP 1502
LR +S+ + P+ R TA + + + R N +NIQM+++ +E IF S S E +I+ ++ + + ++ L V+ LP + G++I+ H + A+ + PY+ L +PQMP W+++ GWT+Y ++ + KV+ PEEN ++FDVE + +AVAV + WYSW SK L++ S++ DLIPL + + S+P + ++GH VSFDRA I+++Y +KG+ RF+DTMS+ +AI G+T QRSL ++ + L + PE + S +W+ +S+N+L DV+ Y L K+ R+ F+KG+++D+ N+FQ LM YCATDV+ T ++F + + + R PHP +F GMLEMG YLPVN + YI A TYE + ++ K+ LM LA + ++ Y DPWLWDLDW KK P
Sbjct: 2 LRLVSHQPWRCSPAAVWRRRCTAAAEAKHQQNSKETRTNPLNIQMLSRNLREQIFRS-SVQEYADEDIDRSIRHLEKHSLWGKEAVLLPEVELKLPQMYGDDIDEHFRILAQKQSLPYLEAASQLQQAHLPQMPQKWAWEVGWTRYG-LDGQCKKVNFPEENAVVFDVEVCMAEGRCPTLAVAVSPTAWYSWCSKRLVEERYTWSSQLTLADLIPLETPSNSSRPPGGQWKERLVIGHNVSFDRAHIKEQYLLKGSKMRFLDTMSLHMAISGLTGFQRSLWMASRHGKRRG----LQEVKEHIKKLGRRPEGPMIGSWEWVNISSINNLTDVHALYVGGEPLK--KEPRDIFVKGSMNDVRNNFQELMQYCATDVLATHEVFTQQLSLFMERCPHPVTFAGMLEMGVSYLPVNESWGRYIEDAQDTYEELQREMKKSLMILADDACQLLQDDRYKEDPWLWDLDWDVQEFKKKKMP 469
BLAST of DNA polymerase subunit gamma vs. Ensembl Cavefish
Match: polg (DNA polymerase gamma, catalytic subunit [Source:NCBI gene;Acc:103040749]) HSP 1 Score: 467.233 bits (1201), Expect = 1.683e-144 Identity = 277/702 (39.46%), Postives = 374/702 (53.28%), Query Frame = 3
Query: 1494 SFPKWFRVLVSK--NENSNTFNP--DLITSQKSIAVKMLKLKWDGLPLHYDKKNKWGVLIPGCYLPVWYDEKFMDISNKLIWPIIPVERISPSYIDYFQFPLQKYVQFWVPLFVSRLEAFRDFLLSLGNSDLTKYNVFVEY-MMAIVEPINFTPENLTKVNSLLCEIKEITLRNSKGYYNSNEEGPLSLYNFQMNDFSSLFAKTKCLLTENPIIPFVWFLPLPHEKGEGNTVGSPFSKSFLNYMQSGRLTSHAANNLLEIMIEGKKSGVFWRNYQNRVQSQFMV--------RT-------SKENNESAIIPQVIVAGTVTRRSVERLWLTATNSTNDRVGSELKAMVQTPTNWVMVGADVDSQEQWIAAVLGDS-VTGIHGGTPFGWMVLQGSKVDGTDLHSKTSKMIGISRNAAKVLNYSRMYGAGIKSSTDTLLKYNPELKPQEAFNKIKDLMKQTKGKR-----SQGKWV-----------------------------------------------DGIESEVFSKLEEIAKSDEPSTPVLNARLSQALEKRVVNEKFMTSKCNWVVQSSGVDYLHCLLTFTKHLIQLYNVNARLCICIHDEIRYLCEEKDKYRLALILQIANLYTRSVFSMKLNLFDLPQSIAFFSEIDIDYCLRKSPTDDCITPSNQNGLLNNYNIQKGESLNIYQILDKTGGRL 3380
P W+R L ++ + ++P LIT Q + K++ L WDG PLHY K+ WG L+PG +D + P+ P I Y +Y + + PL + ++ D +L+ D + + E M+ +V P + + ++ + Y++ N GP + N IP VWF LPH+ G N VGSPFSK FL+ M+ G L S +E K FWRN Q R+ SQ +V RT +E AI+PQV+ AGTVTRR+VE WLTA+N+ DRVGSELKAMVQ P + +VGADVDSQE WIAAVLG+S G+HG T FGWM LQG K GTDLHS+T+ +GISR AKV NY R+YGAG + L+++N L EA +K K + TKG R +G+W+ G ESE+F+KLE IA S++P+TPVL R+S+ALE V ++F+TS+ NWVVQSS VDYLH +L + L++ ++++ R CI IHDE+RYL + +D+YR AL LQI NL TR +F+ KL + DLPQS+AFFS +DID CLRK T DC TPSN GL + I +GE+L+IYQI++KT G L
Sbjct: 538 GHPGWYRKLCARMSEKEDEAWSPGASLITLQMRLTPKLMGLTWDGFPLHYTDKHGWGYLVPG-------HRDNLDTTEDSEGPVCPHRAIEAIYREYCEEKGKGK-----PLCLDNQQS-DDLMLT----DSSVWQTVEELSMLEVVSDDEAVPRTVRPKKAQRSSLELDAGESECPYHHGN--GPYNDVN----------------------IPGVWFFKLPHKDGNENNVGSPFSKDFLSKMEDGTLHSGRGETNATRALEINKMMSFWRNAQKRISSQMVVWLRKGELPRTVSRHEDYDEEGQYGAILPQVVTAGTVTRRAVEPTWLTASNARRDRVGSELKAMVQVPPGYHLVGADVDSQELWIAAVLGESHFAGMHGCTAFGWMTLQGKKSQGTDLHSRTANAVGISREHAKVFNYGRIYGAGQPFAERLLMQFNHRLSQPEAADKAKQMYALTKGLRRYHLSEEGEWLVNELGVDVNWDEYGTVSREELRRISKLAGTSFRNKKRWDLVGRRVWAGGTESEMFNKLESIAHSEQPATPVLGCRISRALEPAAVKDEFITSRVNWVVQSSAVDYLHLMLVAMRWLLEEFDIDGRFCISIHDEVRYLVKSEDRYRAALALQITNLLTRCMFAYKLGMKDLPQSVAFFSAVDIDQCLRKEVTMDCATPSNPIGLEGRFGIPQGEALDIYQIIEKTKGSL 1198 HSP 2 Score: 282.337 bits (721), Expect = 2.591e-78 Identity = 166/476 (34.87%), Postives = 262/476 (55.04%), Query Frame = 3
Query: 135 LRFLSYSGYLPKPSNFGRLLNTANS------SDDKLRINMMNIQMINKKFQETIFGSKSTAELDFFEINSLFKNFKIDT---EKTTLNKNVDFDLPPLLGENIEIHLQKAAETLNDPYMALLKGLDDWKIPQMPTMWSFQEGWTKYDTINNKFYKVSVPEENLLIFDVETLPKYTQRAVMAVAVGKSYWYSWTSKYLLDGICKDDSEICKDDLIPLYSNDDKSKP-------KCIVGHFVSFDRARIRDEYCIKGTGTRFIDTMSMQIAIRGMTSLQRSLKISFNNNNTENRIWKLYFSNSSKNGMNNSPED-IEESDKWLTEASLNSLVDVYQYYFPNCNLSSLKDKRETFIKGTIDDIVNDFQALMTYCATDVIMTAKIFQKLWTDYRVRFPHPASFTGMLEMGSLYLPVNSNLNTYINRASTTYESMIKKEKEILMELAQKSLA-SKEKEYINDPWLWDLDWSTT--KKSSFP 1502
LR +S+ + P+ R TA + + + R N +NIQM+++ +E IF S S E +I+ ++ + + ++ L V+ LP + G++I+ H + A+ + PY+ L +PQMP W+++ GWT+Y ++ + KV+ PEEN ++FDVE + +AVAV + WYSW SK L++ S++ DLIPL + + S+P + ++GH VSFDRA I+++Y +KG+ RF+DTMS+ +AI G+T QRSL ++ + L + PE + S +W+ +S+N+L DV+ Y L K+ R+ F+KG+++D+ N+FQ LM YCATDV+ T ++F + + + R PHP +F GMLEMG YLPVN + YI A TYE + ++ K+ LM LA + ++ Y DPWLWDLDW KK P
Sbjct: 2 LRLVSHQPWRCSPAAVWRRRCTAAAEAKHQQNSKETRTNPLNIQMLSRNLREQIFRS-SVQEYADEDIDRSIRHLEKHSLWGKEAVLLPEVELKLPQMYGDDIDEHFRILAQKQSLPYLEAASQLQQAHLPQMPQKWAWEVGWTRYG-LDGQCKKVNFPEENAVVFDVEVCMAEGRCPTLAVAVSPTAWYSWCSKRLVEERYTWSSQLTLADLIPLETPSNSSRPPGGQWKERLVIGHNVSFDRAHIKEQYLLKGSKMRFLDTMSLHMAISGLTGFQRSLWMASRHGKRRG----LQEVKEHIKKLGRRPEGPMIGSWEWVNISSINNLTDVHALYVGGEPLK--KEPRDIFVKGSMNDVRNNFQELMQYCATDVLATHEVFTQQLSLFMERCPHPVTFAGMLEMGVSYLPVNESWGRYIEDAQDTYEELQREMKKSLMILADDACQLLQDDRYKEDPWLWDLDWDVQEFKKKKMP 469
BLAST of DNA polymerase subunit gamma vs. Ensembl Cavefish
Match: polg (DNA polymerase gamma, catalytic subunit [Source:NCBI gene;Acc:103040749]) HSP 1 Score: 419.083 bits (1076), Expect = 2.867e-127 Identity = 233/523 (44.55%), Postives = 297/523 (56.79%), Query Frame = 3
Query: 1971 CEIKEITLRNSKGYYNSNEEGPLSLYNFQMNDFSSLFAKTKCLLTENPIIPFVWFLPLPHEKGEGNTVGSPFSKSFLNYMQSGRLTSHAANNLLEIMIEGKKSGVFWRNYQNRVQSQFMV--------RT-------SKENNESAIIPQVIVAGTVTRRSVERLWLTATNSTNDRVGSELKAMVQTPTNWVMVGADVDSQEQWIAAVLGDS-VTGIHGGTPFGWMVLQGSKVDGTDLHSKTSKMIGISRNAAKVLNYSRMYGAGIKSSTDTLLKYNPELKPQEAFNKIKDLMKQTKGKR-----SQGKWV-----------------------------------------------DGIESEVFSKLEEIAKSDEPSTPVLNARLSQALEKRVVNEKFMTSKCNWVVQSSGVDYLHCLLTFTKHLIQLYNVNARLCICIHDEIRYLCEEKDKYRLALILQIANLYTRSVFSMKLNLFDLPQSIAFFSEIDIDYCLRKSPTDDCITPSNQNGLLNNYNIQKGE 3335
C + ++ LR+S E P N ND + IP VWF LPH+ G N VGSPFSK FL+ M+ G L S +E K FWRN Q R+ SQ +V RT +E AI+PQV+ AGTVTRR+VE WLTA+N+ DRVGSELKAMVQ P + +VGADVDSQE WIAAVLG+S G+HG T FGWM LQG K GTDLHS+T+ +GISR AKV NY R+YGAG + L+++N L EA +K K + TKG R +G+W+ G ESE+F+KLE IA S++P+TPVL R+S+ALE V ++F+TS+ NWVVQSS VDYLH +L + L++ ++++ R CI IHDE+RYL + +D+YR AL LQI NL TR +F+ KL + DLPQS+AFFS +DID CLRK T DC TPSN GL + I +GE
Sbjct: 615 CLLVKLDLRSSLELDAGESECPYHHGNGPYNDVN---------------IPGVWFFKLPHKDGNENNVGSPFSKDFLSKMEDGTLHSGRGETNATRALEINKMMSFWRNAQKRISSQMVVWLRKGELPRTVSRHEDYDEEGQYGAILPQVVTAGTVTRRAVEPTWLTASNARRDRVGSELKAMVQVPPGYHLVGADVDSQELWIAAVLGESHFAGMHGCTAFGWMTLQGKKSQGTDLHSRTANAVGISREHAKVFNYGRIYGAGQPFAERLLMQFNHRLSQPEAADKAKQMYALTKGLRRYHLSEEGEWLVNELGVDVNWDEYGTVSREELRRISKLAGTSFRNKKRWDLVGRRVWAGGTESEMFNKLESIAHSEQPATPVLGCRISRALEPAAVKDEFITSRVNWVVQSSAVDYLHLMLVAMRWLLEEFDIDGRFCISIHDEVRYLVKSEDRYRAALALQITNLLTRCMFAYKLGMKDLPQSVAFFSAVDIDQCLRKEVTMDCATPSNPIGLEGRFGIPQGE 1122 HSP 2 Score: 279.256 bits (713), Expect = 1.419e-77 Identity = 159/440 (36.14%), Postives = 248/440 (56.36%), Query Frame = 3
Query: 225 RINMMNIQMINKKFQETIFGSKSTAELDFFEINSLFKNFKIDT---EKTTLNKNVDFDLPPLLGENIEIHLQKAAETLNDPYMALLKGLDDWKIPQMPTMWSFQEGWTKYDTINNKFYKVSVPEENLLIFDVETLPKYTQRAVMAVAVGKSYWYSWTSKYLLDGICKDDSEICKDDLIPLYSNDDKSKP-------KCIVGHFVSFDRARIRDEYCIKGTGTRFIDTMSMQIAIRGMTSLQRSLKISFNNNNTENRIWKLYFSNSSKNGMNNSPED-IEESDKWLTEASLNSLVDVYQYYFPNCNLSSLKDKRETFIKGTIDDIVNDFQALMTYCATDVIMTAKIFQKLWTDYRVRFPHPASFTGMLEMGSLYLPVNSNLNTYINRASTTYESMIKKEKEILMELAQKSLA-SKEKEYINDPWLWDLDWSTT--KKSSFP 1502
R N +NIQM+++ +E IF S S E +I+ ++ + + ++ L V+ LP + G++I+ H + A+ + PY+ L +PQMP W+++ GWT+Y ++ + KV+ PEEN ++FDVE + +AVAV + WYSW SK L++ S++ DLIPL + + S+P + ++GH VSFDRA I+++Y +KG+ RF+DTMS+ +AI G+T QRSL ++ + L + PE + S +W+ +S+N+L DV+ Y L K+ R+ F+KG+++D+ N+FQ LM YCATDV+ T ++F + + + R PHP +F GMLEMG YLPVN + YI A TYE + ++ K+ LM LA + ++ Y DPWLWDLDW KK P
Sbjct: 33 RTNPLNIQMLSRNLREQIFRS-SVQEYADEDIDRSIRHLEKHSLWGKEAVLLPEVELKLPQMYGDDIDEHFRILAQKQSLPYLEAASQLQQAHLPQMPQKWAWEVGWTRYG-LDGQCKKVNFPEENAVVFDVEVCMAEGRCPTLAVAVSPTAWYSWCSKRLVEERYTWSSQLTLADLIPLETPSNSSRPPGGQWKERLVIGHNVSFDRAHIKEQYLLKGSKMRFLDTMSLHMAISGLTGFQRSLWMASRHGKRRG----LQEVKEHIKKLGRRPEGPMIGSWEWVNISSINNLTDVHALYVGGEPLK--KEPRDIFVKGSMNDVRNNFQELMQYCATDVLATHEVFTQQLSLFMERCPHPVTFAGMLEMGVSYLPVNESWGRYIEDAQDTYEELQREMKKSLMILADDACQLLQDDRYKEDPWLWDLDWDVQEFKKKKMP 464 HSP 3 Score: 53.5286 bits (127), Expect = 1.522e-6 Identity = 24/62 (38.71%), Postives = 35/62 (56.45%), Query Frame = 3
Query: 1494 SFPKWFRVLVSK--NENSNTFNP--DLITSQKSIAVKMLKLKWDGLPLHYDKKNKWGVLIPG 1667
P W+R L ++ + ++P LIT Q + K++ L WDG PLHY K+ WG L+PG
Sbjct: 533 GHPGWYRKLCARMSEKEDEAWSPGASLITLQMRLTPKLMGLTWDGFPLHYTDKHGWGYLVPG 594
BLAST of DNA polymerase subunit gamma vs. Ensembl Sea Lamprey
Match: polg (polymerase (DNA directed), gamma [Source:ZFIN;Acc:ZDB-GENE-060303-1]) HSP 1 Score: 246.514 bits (628), Expect = 1.356e-69 Identity = 146/461 (31.67%), Postives = 234/461 (50.76%), Query Frame = 3
Query: 207 SSDDKLRINMMNIQMINKKFQETIF-GSKSTAELDFFEIN-SLFKNFKIDTEKTTLNKNVDFDLPPLLGENIEIHLQKAAETLNDPYMALLKGLDDW-KIPQMPTMWSFQEGWTKYDTINNKFYKVSVPEENLLIFDVETLPKYTQRAVMAVAVGKSYWYSWTSKYLLDGICKDDSEICKDDLIPL-------------------YSNDDKSKPKCIVGHFVSFDRARIRDEYCIKGTGTRFIDTMSMQIAIRGMTSLQRSLKISFNNNNTENRIWKLYFSNSSKNGMNNSPEDIEESDK-----------WLTEASLNSLVDVYQYYFPNCNLSSLKDKRETFIKGTIDDIVNDFQALMTYCATDVIMTAKIFQKLWTDYRVRFPHPASFTGMLEMGSLYLPVNSNLNTYINRASTTYESMIKKEKEILMELAQKSLASKEKE-YINDPWLWDLDWSTTK 1487
S D+ R+N +NIQM+++ E IF G +S+ + +++ + L K+V LPPLLG++++ H + A + Y+ GL +P +P W ++ GWT+Y + V P+E L+FDVE +AVA + WYSW S+ L++ ++ DLIP+ S+ S + +VGH VSFDRA +R++Y + T RF+DTMS+ +AI G+T QRSL ++ + + G+ E + + + W+ +S+N+LVDV+ Y L K++R+ F+KG+++D+ FQ LM+YCA DV T ++F + + R PHP + GMLEMG YLPVN N Y++ + TY+ + ++ K+ LM LA ++ + E Y +DPW WD DWST +
Sbjct: 1 SERDETRMNPLNIQMLSRNLHEQIFKGVESSHPEESVQLSKEHLSQHGLWGRDGALLKDVHLRLPPLLGDSVDGHFRALATRQSLGYVRAACGLVACSALPALPREWRYEAGWTRYGP-DGHVEAVPFPDEPGLVFDVEVCVTEGHCPTLAVACSPAAWYSWCSRRLVERRFSWPQQLSLQDLIPMESGSGSRSSASSSSTSSSSSSSQGDSTERLVVGHNVSFDRAHVREQYQLATTRLRFLDTMSLHMAISGLTGFQRSLWMASRHGK--------------RRGLQEVQEHMARTRQKFDGPAMGAWDWVDVSSINNLVDVHGLYVGGQALQ--KEERDVFVKGSMEDVRGSFQELMSYCARDVKATHEVFCQQLPLFMKRCPHPVTLAGMLEMGQCYLPVNHNWERYVSESHDTYQELQREMKQSLMSLANEACGLLQGERYKDDPWFWDQDWSTQE 444 HSP 2 Score: 51.6026 bits (122), Expect = 9.701e-7 Identity = 21/59 (35.59%), Postives = 32/59 (54.24%), Query Frame = 3
Query: 1494 SFPKWFRVLVSKNENSN-TFNPDLITSQKSIAVKMLKLKWDGLPLHYDKKNKWGVLIPG 1667
P W+R L + + P L++ Q + K+L+L WDG PLH+ + WG L+PG
Sbjct: 520 GHPAWYRKLCPPPSDPEWSPGPSLLSLQMRLTPKLLRLSWDGFPLHHTTPHGWGYLVPG 578
BLAST of DNA polymerase subunit gamma vs. Ensembl Yeast
Match: MIP1 (Mitochondrial DNA polymerase gamma; single subunit of mitochondrial DNA polymerase in yeast, in contrast to metazoan complex of catalytic and accessory subunits; polymorphic in yeast, petites occur more frequently in some lab strains; human ortholog POLG complements yeast mip1 mutant; mutations in human POLG associated with Alpers-Huttenlocher syndrome (AHS), progressive external ophthalmoplegia (PEO), parkinsonism, other mitochondrial diseases [Source:SGD;Acc:S000005857]) HSP 1 Score: 373.629 bits (958), Expect = 9.232e-111 Identity = 189/437 (43.25%), Postives = 278/437 (63.62%), Query Frame = 3
Query: 2142 LPHEKGEGNTVGSPFSKSFLNYMQSGRLTSHAANNLLEIMIEGKKSGVFWRNYQNRVQSQFMVRTSKENNE------------------SAIIPQVIVAGTVTRRSVERLWLTATNSTNDRVGSELKAMVQTPTNWVMVGADVDSQEQWIAAVLGDSVTGIHGGTPFGWMVLQGSKVDGTDLHSKTSKMIGISRNAAKVLNYSRMYGAGIKSSTDTLLKYNPELKPQEAFNKIKDLMKQTKGKRSQGK-----WVDGIESEVFSKLEEIAKSDEPSTPVLNARLSQALEKRVVNE-KFMTSKCNWVVQSSGVDYLHCLLTFTKHLIQLYNVNARLCICIHDEIRYLCEEKDKYRLALILQIANLYTRSVFSMKLNLFDLPQSIAFFSEIDIDYCLRKSPTDDCITPSNQNGLLNNYNIQKGESLNIYQILDKTGGRL 3380
+PH G + +KS+ ++ + G L S + L ++ SG +W + + R+QSQF+V + K NE + IIP+++ GT+TRR+VE WLTA+N+ +R+GSELK V+ P + VGADVDS+E WIA+++GDS+ +HGGT GWM L+G+K +GTDLH+KT++++G SRN AK+ NY R+YGAG K ++ L ++NP L +E L + TKGK + K W G ES +F+KLE IA+ + P TPVL ++ +L K+ + F+ S+ NW +QSSGVDYLH L +++I+ YN+ ARLCI IHDEIR+L EKDKYR A+ LQI+N++TR++F ++ + +LPQ+ AFFS++DID +RK DCITPSN+ I GE+L+I Q+LDK+ +L
Sbjct: 554 VPHPNGPTFNCTNLLTKSYNHFFEKGVLKSES--ELAHQALQINSSGSYWMSARERIQSQFVVPSCKFPNEFQSLSAKSSLNNEKTNDLAIIIPKIVPMGTITRRAVENAWLTASNAKANRIGSELKTQVKAPPGYCFVGADVDSEELWIASLVGDSIFNVHGGTAIGWMCLEGTKNEGTDLHTKTAQILGCSRNEAKIFNYGRIYGAGAKFASQLLKRFNPSLTDEETKKIANKLYENTKGKTKRSKLFKKFWYGGSESILFNKLESIAEQETPKTPVLGCGITYSLMKKNLRANSFLPSRINWAIQSSGVDYLHLLCCSMEYIIKKYNLEARLCISIHDEIRFLVSEKDKYRAAMALQISNIWTRAMFCQQMGINELPQNCAFFSQVDIDSVIRKEVNMDCITPSNKTA------IPHGEALDINQLLDKSNSKL 982 HSP 2 Score: 212.616 bits (540), Expect = 1.617e-56 Identity = 156/521 (29.94%), Postives = 257/521 (49.33%), Query Frame = 3
Query: 183 GRLLNTANSSDDKLRINMMNIQMINKKFQETIFGS-------KSTAELDFFEINSLFKNFKIDTEKTTLNKNVDFDLPPLLGENIEIHLQKAAETLNDPYMALLKGLDDWKIPQM---PTMWSFQEGWTKYDTINNKFYKVSVPEENLLIFDVETLPKYTQRAVMAVAVGKSYWYSWTSKYLLDGICKDDSEICKDDLIPLYSNDDKSKPKCIVGHFVSFDRARIRDEYCIKGTGTRFIDTMSMQIAIRGMTSLQRSLKISFNNNNTENRIWKLYFSNSSKNGMNNSPEDIEESDKWLTEASLNSLVDVYQYYFPNCNLSSLKDKRETFIKGTIDDIVNDFQALMTYCATDVIMTAKIFQKLWTDYRVRFPHPASFTGMLEMGSLYLPVNSN-LNTYINRASTTY-ESMIKKEKEILMELAQKSLASKEKE-YINDPWLWDLDWST-----TKKS---------SFPKWFRVLVSKNENSNTFNPDLITSQKSIAVKMLKLKWDGLPLHYDKKNKWGVLIP 1664
R +T ++ + RIN + IQ + + Q +FGS + + +L SL K+ + +KT + + F LPPL G +++ H QK ++PY + + K +M P W + GW KY +V+ P+E L++FDVETL + +A A+ + WY W S ++ G DD LIPL + +K + I+GH V++DRAR+ +EY + + F+DT S+ IA G+ S QR + + NN E + S+ S ED + D WL ++LNSL DV +++ C + K R+ F I+ +FQ L+ YCATDV T+++F +++ + + PHP SF G+ + LP N N Y+N + + Y +S ++ E +I+ + L + + Y+ DPWL LDW+T TKK FP+W+R L + +T P + + I + + KL W+ P+ + K++ W +P
Sbjct: 26 ARWFSTKKNTAEAPRINPVGIQYLGESLQRQVFGSCGGKDEVEQSDKLMELSKKSL-KDHGLWGKKTLITDPISFPLPPLQGRSLDEHFQKIGRFNSEPYKSFCED----KFTEMVARPAEWLRKPGWVKY-VPGMAPVEVAYPDEELVVFDVETLYNVSDYPTLATALSSTAWYLWCSPFICGG---DDPAA----LIPL---NTLNKEQVIIGHNVAYDRARVLEEYNFRDSKAFFLDTQSLHIASFGLCSRQRPMFMK-NNKKKEAEV-------ESEVHPEISIEDYD--DPWLNVSALNSLKDVAKFH---CKIDLDKTDRDFFASTDKSTIIENFQKLVNYCATDVTATSQVFDEIFPVFLKKCPHPVSFAGLKSLSKCILPTKLNDWNDYLNSSESLYQQSKVQIESKIVQIIKDIVLLKDKPDFYLKDPWLSQLDWTTKPLRLTKKGVPAKCQKLPGFPEWYRQLFP---SKDTVEPKITIKSRIIPI-LFKLSWENSPVIWSKESGWCFNVP 513
BLAST of DNA polymerase subunit gamma vs. Ensembl Nematostella
Match: EDO28790 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T5H3]) HSP 1 Score: 74.7146 bits (182), Expect = 8.905e-16 Identity = 44/136 (32.35%), Postives = 69/136 (50.74%), Query Frame = 3
Query: 225 RINMMNIQMINKKFQETIFG--SKSTAELDFFE--INSLFKNFKIDTEKTTLNKNVDFDLPPLLGENIEIHLQKAAETLNDPYMALLKGLDDWKIPQMPTMWSFQEGWTKY--DTINNKFYKVSVPEENLLIFDVE 614
R N +NIQM++ E +F +T D + I L + K+ ++VD LPPLLGENI+ H + A ++ Y + + + +P +P MW F+ GW +Y DT +V P ++ L+FDVE
Sbjct: 1 RYNPVNIQMLSASLHEQLFPDTPANTQSTDVIQKCIEHLSAHGLWGKAKSAA-RDVDMTLPPLLGENIDDHFRTIARQQSNAYYDMSQDIASSSLPSVPDMWEFRAGWCRYTEDTDGLHVTQVECPPDDALVFDVE 135
BLAST of DNA polymerase subunit gamma vs. Ensembl Medaka
Match: polg (DNA polymerase gamma, catalytic subunit [Source:NCBI gene;Acc:101156890]) HSP 1 Score: 457.988 bits (1177), Expect = 6.232e-142 Identity = 278/705 (39.43%), Postives = 369/705 (52.34%), Query Frame = 3
Query: 1494 SFPKWFRVLVSKNENSNTFNP--DLITSQKSIAVKMLKLKWDGLPLHYDKKNKWGVLIPGCYLPVWYDEKFMDISNKLIWPIIPVERISPSYIDYFQFPLQKYVQFWVPLFVSRLEAFRDFLLSLGNSD---LTKYNVF--VEYMMAIVEPINFTPENLTKVNSLLCEIKEITLRNSKGYYNSNEEGPLSLY--NFQMNDFSSLFAKTKCLLTENPIIPFVWFLPLPHEKGEGNTVGSPFSKSFLNYMQSGRLTSHAANNLLEIMIEGKKSGVFWRNYQNRVQSQFMVRTSK---------------ENNESAIIPQVIVAGTVTRRSVERLWLTATNSTNDRVGSELKAMVQTPTNWVMVGADVDSQEQWIAAVLGDS-VTGIHGGTPFGWMVLQGSKVDGTDLHSKTSKMIGISRNAAKVLNYSRMYGAGIKSSTDTLLKYNPELKPQEAFNKIKDLMKQTKGKR-----SQGKWV----------------------------------------------DGIESEVFSKLEEIAKSDEPSTPVLNARLSQALEKRVVNEKFMTSKCNWVVQSSGVDYLHCLLTFTKHLIQLYNVNARLCICIHDEIRYLCEEKDKYRLALILQIANLYTRSVFSMKLNLFDLPQSIAFFSEIDIDYCLRKSPTDDCITPSNQNGLLNNYNIQKGESLNIYQILDKTGGRL 3380
P W+R L K + ++P LI+ Q + K++ L WDG PLHY +K+ WG L+PG + + + + P+ P I Y +Y + + VQ L G+SD T +V+ VE M ++ ENL+ N + + R S EE + N ND + IP WF LPH+ G N VGSPFSK FL M+ G L + + +E K FWRN R+ SQ +V K E AI+PQV+ AGTVTRR+VE WLTA+N+ DRVGSELKAMVQ P + +VGADVDSQE WIAAVLG++ G+HG T FGWM LQG K GTDLHS+T+ +GISR AKV NY R+YGAG + L+++N L EA +K + + TKG R +G+W+ G ES++F+KLE IA+S +P+TPVL+ R+S+ALE + V +F+TS+ NWVVQSS VDYLH +L K L + +N++ R CI IHDE+RYL +D+YR AL LQI NL TRSVF+ L L DLPQS+AFFS +D+D CLRK DC+TPSN GL Y + GE+L+IYQI++ T G L
Sbjct: 438 GHPGWYRKLCEKMSQEDGWSPGASLISLQMRLTPKLMGLMWDGFPLHYTEKHGWGYLVPG-------RKDNLSPAGENTDPVCPHRSIERIYKEYCE--QNRKVQ--------------PKSLDSGDSDDLIWTDSSVWEKVEEMSSL--------ENLSDENGIGTVQSDTKRRKSPDPLLFPEESHCHYHHGNGPYNDIN---------------IPGCWFFKLPHKDGNHNNVGSPFSKDFLVKMEDGTLRAGRGGTNATLALEINKMMSFWRNAHKRISSQMVVWLRKGELPRNVSRHKDFDEEGQYGAILPQVVTAGTVTRRAVEPTWLTASNARRDRVGSELKAMVQVPPGYHLVGADVDSQELWIAAVLGEAHFAGMHGCTAFGWMTLQGKKSQGTDLHSRTADAVGISREHAKVFNYGRIYGAGQPFAERLLMQFNHRLNQMEAASKARQMYALTKGIRRYHLSEEGEWLVNELGIDVQREEDGSVSLQELRRISKVASHSSRRKKWDIVGKRVWAGGTESDMFNKLESIAQSAQPATPVLHCRISRALEPKAVRNEFITSRVNWVVQSSAVDYLHLMLVAMKWLFEEHNIDGRFCISIHDEVRYLVRSEDRYRAALALQITNLLTRSVFAHALGLQDLPQSVAFFSSVDVDQCLRKEVIMDCVTPSNPTGLERRYGLPPGEALDIYQIINITDGSL 1096 HSP 2 Score: 206.838 bits (525), Expect = 6.263e-54 Identity = 135/420 (32.14%), Postives = 214/420 (50.95%), Query Frame = 3
Query: 249 MINKKFQETIFGS---KSTAELDFFEINSLFKNFKIDTEKTTLNKNVDFDLPPLLGENIEIHLQKAAETLNDPYMALLKGLDDWKIPQMPTMWSFQEGWTKYDTINNKFYKVSVPEENLLIFDVETLPKYTQRAVMAVAVGKSYWYSWTSKYLLDGICKDDSEICKDDLIPLYSNDDKSKP-------KCIVGHFVSFDRARIRDEYCIKGTGTRFIDTMSMQIAIRGMTSLQRSLKISFNNNNTENRIWKLYFSNSSKNGMNNSPEDIEESDKWLTEASLNSLVDVYQYYFPNCNLSSLKDKRETFIKGTIDDIVNDFQALMTYCATDVIMTAKIFQKLWTDYRVRFPHPASFTGMLEMGSLYLPVNSNLNTYINRASTTYESMIKKEKEILMELAQKSLA-SKEKEYINDPWLWDLDW 1475
M++K E IF + + E I L K+ ++ ++T+L +V+ LP + G+NI+ H + AE + PY+ + L ++P MP WS++ GWT+Y N KV P+E+ L+FDVE + +AVA+ + WYSW SK LL+ +++ +LIPL + + S+P + IVGH VSFDR+ I+++Y +KG+ RF+DTMS+ +AI G+T QR+L ++ N++ K K G+ E I+++ + KR+ ++ LM YCA DV T ++F + + R PHP +F GMLEMG YLPVN N + Y+ Y+ + ++ K+ LM LA + ++ Y DPWLWDL+W
Sbjct: 1 MLSKNLHEQIFRGVVPEYSEEAVERSIKHLQKH-QLWGKETSLLPDVELKLPQMYGKNIDEHFRILAEKQSLPYLEAVTKLLQAELPSMPQEWSWEVGWTRYGP-NGGTQKVDFPDESALVFDVEVCMTEGRCPTLAVALSPTNWYSWCSKRLLEERYSWSNQLSLAELIPLETPLNSSRPPGGQWKERLIVGHNVSFDRSHIKEQYLLKGSIVRFLDTMSLHMAISGLTGFQRTLWMA-------NKLGK-------KRGLQEVKEHIKKTGQ----------------------------KRDGPVE------------LMQYCALDVEATHQVFTEQMPLFMERCPHPVTFAGMLEMGVSYLPVNQNWHRYLEDCQDVYDDLQREMKKSLMTLADDACQLLQDARYKEDPWLWDLEW 364
BLAST of DNA polymerase subunit gamma vs. Ensembl Medaka
Match: polg (DNA polymerase gamma, catalytic subunit [Source:NCBI gene;Acc:101156890]) HSP 1 Score: 457.603 bits (1176), Expect = 7.247e-141 Identity = 278/705 (39.43%), Postives = 369/705 (52.34%), Query Frame = 3
Query: 1494 SFPKWFRVLVSKNENSNTFNP--DLITSQKSIAVKMLKLKWDGLPLHYDKKNKWGVLIPGCYLPVWYDEKFMDISNKLIWPIIPVERISPSYIDYFQFPLQKYVQFWVPLFVSRLEAFRDFLLSLGNSD---LTKYNVF--VEYMMAIVEPINFTPENLTKVNSLLCEIKEITLRNSKGYYNSNEEGPLSLY--NFQMNDFSSLFAKTKCLLTENPIIPFVWFLPLPHEKGEGNTVGSPFSKSFLNYMQSGRLTSHAANNLLEIMIEGKKSGVFWRNYQNRVQSQFMVRTSK---------------ENNESAIIPQVIVAGTVTRRSVERLWLTATNSTNDRVGSELKAMVQTPTNWVMVGADVDSQEQWIAAVLGDS-VTGIHGGTPFGWMVLQGSKVDGTDLHSKTSKMIGISRNAAKVLNYSRMYGAGIKSSTDTLLKYNPELKPQEAFNKIKDLMKQTKGKR-----SQGKWV----------------------------------------------DGIESEVFSKLEEIAKSDEPSTPVLNARLSQALEKRVVNEKFMTSKCNWVVQSSGVDYLHCLLTFTKHLIQLYNVNARLCICIHDEIRYLCEEKDKYRLALILQIANLYTRSVFSMKLNLFDLPQSIAFFSEIDIDYCLRKSPTDDCITPSNQNGLLNNYNIQKGESLNIYQILDKTGGRL 3380
P W+R L K + ++P LI+ Q + K++ L WDG PLHY +K+ WG L+PG + + + + P+ P I Y +Y + + VQ L G+SD T +V+ VE M ++ ENL+ N + + R S EE + N ND + IP WF LPH+ G N VGSPFSK FL M+ G L + + +E K FWRN R+ SQ +V K E AI+PQV+ AGTVTRR+VE WLTA+N+ DRVGSELKAMVQ P + +VGADVDSQE WIAAVLG++ G+HG T FGWM LQG K GTDLHS+T+ +GISR AKV NY R+YGAG + L+++N L EA +K + + TKG R +G+W+ G ES++F+KLE IA+S +P+TPVL+ R+S+ALE + V +F+TS+ NWVVQSS VDYLH +L K L + +N++ R CI IHDE+RYL +D+YR AL LQI NL TRSVF+ L L DLPQS+AFFS +D+D CLRK DC+TPSN GL Y + GE+L+IYQI++ T G L
Sbjct: 536 GHPGWYRKLCEKMSQEDGWSPGASLISLQMRLTPKLMGLMWDGFPLHYTEKHGWGYLVPG-------RKDNLSPAGENTDPVCPHRSIERIYKEYCE--QNRKVQ--------------PKSLDSGDSDDLIWTDSSVWEKVEEMSSL--------ENLSDENGIGTVQSDTKRRKSPDPLLFPEESHCHYHHGNGPYNDIN---------------IPGCWFFKLPHKDGNHNNVGSPFSKDFLVKMEDGTLRAGRGGTNATLALEINKMMSFWRNAHKRISSQMVVWLRKGELPRNVSRHKDFDEEGQYGAILPQVVTAGTVTRRAVEPTWLTASNARRDRVGSELKAMVQVPPGYHLVGADVDSQELWIAAVLGEAHFAGMHGCTAFGWMTLQGKKSQGTDLHSRTADAVGISREHAKVFNYGRIYGAGQPFAERLLMQFNHRLNQMEAASKARQMYALTKGIRRYHLSEEGEWLVNELGIDVQREEDGSVSLQELRRISKVASHSSRRKKWDIVGKRVWAGGTESDMFNKLESIAQSAQPATPVLHCRISRALEPKAVRNEFITSRVNWVVQSSAVDYLHLMLVAMKWLFEEHNIDGRFCISIHDEVRYLVRSEDRYRAALALQITNLLTRSVFAHALGLQDLPQSVAFFSSVDVDQCLRKEVIMDCVTPSNPTGLERRYGLPPGEALDIYQIINITDGSL 1194 HSP 2 Score: 263.462 bits (672), Expect = 4.387e-72 Identity = 157/428 (36.68%), Postives = 239/428 (55.84%), Query Frame = 3
Query: 225 RINMMNIQMINKKFQETIFGS---KSTAELDFFEINSLFKNFKIDTEKTTLNKNVDFDLPPLLGENIEIHLQKAAETLNDPYMALLKGLDDWKIPQMPTMWSFQEGWTKYDTINNKFYKVSVPEENLLIFDVETLPKYTQRAVMAVAVGKSYWYSWTSKYLLDGICKDDSEICKDDLIPLYSNDDKSKP-------KCIVGHFVSFDRARIRDEYCIKGTGTRFIDTMSMQIAIRGMTSLQRSLKISFNNNNTENRIWKLYFSNSSKNGMNNSPEDIEESDKWLTEASLNSLVDVYQYYFPNCNLSSLKDKRETFIKGTIDDIVNDFQALMTYCATDVIMTAKIFQKLWTDYRVRFPHPASFTGMLEMGSLYLPVNSNLNTYINRASTTYESMIKKEKEILMELAQKSLA-SKEKEYINDPWLWDLDW 1475
R+N + IQM++K E IF + + E I L K+ ++ ++T+L +V+ LP + G+NI+ H + AE + PY+ + L ++P MP WS++ GWT+Y N KV P+E+ L+FDVE + +AVA+ + WYSW SK LL+ +++ +LIPL + + S+P + IVGH VSFDR+ I+++Y +KG+ RF+DTMS+ +AI G+T QR+L ++ N + R + + K G I D W+ +S+N+L DVY Y L K+ RE FIKG + D+ N+FQ LM YCA DV T ++F + + R PHP +F GMLEMG YLPVN N + Y+ Y+ + ++ K+ LM LA + ++ Y DPWLWDL+W
Sbjct: 42 RLNPLKIQMLSKNLHEQIFRGVVPEYSEEAVERSIKHLQKH-QLWGKETSLLPDVELKLPQMYGKNIDEHFRILAEKQSLPYLEAVTKLLQAELPSMPQEWSWEVGWTRYGP-NGGTQKVDFPDESALVFDVEVCMTEGRCPTLAVALSPTNWYSWCSKRLLEERYSWSNQLSLAELIPLETPLNSSRPPGGQWKERLIVGHNVSFDRSHIKEQYLLKGSIVRFLDTMSLHMAISGLTGFQRTLWMA--NKLGKKRGLQEVKEHIKKTGQKRDGPVIGSWD-WVNISSINNLADVYDLYVGGPPLQ--KEAREIFIKGNMTDVRNNFQELMQYCALDVEATHQVFTEQMPLFMERCPHPVTFAGMLEMGVSYLPVNQNWHRYLEDCQDVYDDLQREMKKSLMTLADDACQLLQDARYKEDPWLWDLEW 462
BLAST of DNA polymerase subunit gamma vs. Ensembl Medaka
Match: polg (DNA polymerase gamma, catalytic subunit [Source:NCBI gene;Acc:101156890]) HSP 1 Score: 457.603 bits (1176), Expect = 7.247e-141 Identity = 278/705 (39.43%), Postives = 369/705 (52.34%), Query Frame = 3
Query: 1494 SFPKWFRVLVSKNENSNTFNP--DLITSQKSIAVKMLKLKWDGLPLHYDKKNKWGVLIPGCYLPVWYDEKFMDISNKLIWPIIPVERISPSYIDYFQFPLQKYVQFWVPLFVSRLEAFRDFLLSLGNSD---LTKYNVF--VEYMMAIVEPINFTPENLTKVNSLLCEIKEITLRNSKGYYNSNEEGPLSLY--NFQMNDFSSLFAKTKCLLTENPIIPFVWFLPLPHEKGEGNTVGSPFSKSFLNYMQSGRLTSHAANNLLEIMIEGKKSGVFWRNYQNRVQSQFMVRTSK---------------ENNESAIIPQVIVAGTVTRRSVERLWLTATNSTNDRVGSELKAMVQTPTNWVMVGADVDSQEQWIAAVLGDS-VTGIHGGTPFGWMVLQGSKVDGTDLHSKTSKMIGISRNAAKVLNYSRMYGAGIKSSTDTLLKYNPELKPQEAFNKIKDLMKQTKGKR-----SQGKWV----------------------------------------------DGIESEVFSKLEEIAKSDEPSTPVLNARLSQALEKRVVNEKFMTSKCNWVVQSSGVDYLHCLLTFTKHLIQLYNVNARLCICIHDEIRYLCEEKDKYRLALILQIANLYTRSVFSMKLNLFDLPQSIAFFSEIDIDYCLRKSPTDDCITPSNQNGLLNNYNIQKGESLNIYQILDKTGGRL 3380
P W+R L K + ++P LI+ Q + K++ L WDG PLHY +K+ WG L+PG + + + + P+ P I Y +Y + + VQ L G+SD T +V+ VE M ++ ENL+ N + + R S EE + N ND + IP WF LPH+ G N VGSPFSK FL M+ G L + + +E K FWRN R+ SQ +V K E AI+PQV+ AGTVTRR+VE WLTA+N+ DRVGSELKAMVQ P + +VGADVDSQE WIAAVLG++ G+HG T FGWM LQG K GTDLHS+T+ +GISR AKV NY R+YGAG + L+++N L EA +K + + TKG R +G+W+ G ES++F+KLE IA+S +P+TPVL+ R+S+ALE + V +F+TS+ NWVVQSS VDYLH +L K L + +N++ R CI IHDE+RYL +D+YR AL LQI NL TRSVF+ L L DLPQS+AFFS +D+D CLRK DC+TPSN GL Y + GE+L+IYQI++ T G L
Sbjct: 536 GHPGWYRKLCEKMSQEDGWSPGASLISLQMRLTPKLMGLMWDGFPLHYTEKHGWGYLVPG-------RKDNLSPAGENTDPVCPHRSIERIYKEYCE--QNRKVQ--------------PKSLDSGDSDDLIWTDSSVWEKVEEMSSL--------ENLSDENGIGTVQSDTKRRKSPDPLLFPEESHCHYHHGNGPYNDIN---------------IPGCWFFKLPHKDGNHNNVGSPFSKDFLVKMEDGTLRAGRGGTNATLALEINKMMSFWRNAHKRISSQMVVWLRKGELPRNVSRHKDFDEEGQYGAILPQVVTAGTVTRRAVEPTWLTASNARRDRVGSELKAMVQVPPGYHLVGADVDSQELWIAAVLGEAHFAGMHGCTAFGWMTLQGKKSQGTDLHSRTADAVGISREHAKVFNYGRIYGAGQPFAERLLMQFNHRLNQMEAASKARQMYALTKGIRRYHLSEEGEWLVNELGIDVQREEDGSVSLQELRRISKVASHSSRRKKWDIVGKRVWAGGTESDMFNKLESIAQSAQPATPVLHCRISRALEPKAVRNEFITSRVNWVVQSSAVDYLHLMLVAMKWLFEEHNIDGRFCISIHDEVRYLVRSEDRYRAALALQITNLLTRSVFAHALGLQDLPQSVAFFSSVDVDQCLRKEVIMDCVTPSNPTGLERRYGLPPGEALDIYQIINITDGSL 1194 HSP 2 Score: 263.462 bits (672), Expect = 4.387e-72 Identity = 157/428 (36.68%), Postives = 239/428 (55.84%), Query Frame = 3
Query: 225 RINMMNIQMINKKFQETIFGS---KSTAELDFFEINSLFKNFKIDTEKTTLNKNVDFDLPPLLGENIEIHLQKAAETLNDPYMALLKGLDDWKIPQMPTMWSFQEGWTKYDTINNKFYKVSVPEENLLIFDVETLPKYTQRAVMAVAVGKSYWYSWTSKYLLDGICKDDSEICKDDLIPLYSNDDKSKP-------KCIVGHFVSFDRARIRDEYCIKGTGTRFIDTMSMQIAIRGMTSLQRSLKISFNNNNTENRIWKLYFSNSSKNGMNNSPEDIEESDKWLTEASLNSLVDVYQYYFPNCNLSSLKDKRETFIKGTIDDIVNDFQALMTYCATDVIMTAKIFQKLWTDYRVRFPHPASFTGMLEMGSLYLPVNSNLNTYINRASTTYESMIKKEKEILMELAQKSLA-SKEKEYINDPWLWDLDW 1475
R+N + IQM++K E IF + + E I L K+ ++ ++T+L +V+ LP + G+NI+ H + AE + PY+ + L ++P MP WS++ GWT+Y N KV P+E+ L+FDVE + +AVA+ + WYSW SK LL+ +++ +LIPL + + S+P + IVGH VSFDR+ I+++Y +KG+ RF+DTMS+ +AI G+T QR+L ++ N + R + + K G I D W+ +S+N+L DVY Y L K+ RE FIKG + D+ N+FQ LM YCA DV T ++F + + R PHP +F GMLEMG YLPVN N + Y+ Y+ + ++ K+ LM LA + ++ Y DPWLWDL+W
Sbjct: 42 RLNPLKIQMLSKNLHEQIFRGVVPEYSEEAVERSIKHLQKH-QLWGKETSLLPDVELKLPQMYGKNIDEHFRILAEKQSLPYLEAVTKLLQAELPSMPQEWSWEVGWTRYGP-NGGTQKVDFPDESALVFDVEVCMTEGRCPTLAVALSPTNWYSWCSKRLLEERYSWSNQLSLAELIPLETPLNSSRPPGGQWKERLIVGHNVSFDRSHIKEQYLLKGSIVRFLDTMSLHMAISGLTGFQRTLWMA--NKLGKKRGLQEVKEHIKKTGQKRDGPVIGSWD-WVNISSINNLADVYDLYVGGPPLQ--KEAREIFIKGNMTDVRNNFQELMQYCALDVEATHQVFTEQMPLFMERCPHPVTFAGMLEMGVSYLPVNQNWHRYLEDCQDVYDDLQREMKKSLMTLADDACQLLQDARYKEDPWLWDLEW 462
BLAST of DNA polymerase subunit gamma vs. Ensembl Medaka
Match: polg (DNA polymerase gamma, catalytic subunit [Source:NCBI gene;Acc:101156890]) HSP 1 Score: 412.92 bits (1060), Expect = 8.953e-125 Identity = 220/475 (46.32%), Postives = 281/475 (59.16%), Query Frame = 3
Query: 2157 GEGNTVGSPFSKSFLNYMQSGRLTSHAANNLLEIMIEGKKSGVFWRNYQNRVQSQFMVRTSK---------------ENNESAIIPQVIVAGTVTRRSVERLWLTATNSTNDRVGSELKAMVQTPTNWVMVGADVDSQEQWIAAVLGDS-VTGIHGGTPFGWMVLQGSKVDGTDLHSKTSKMIGISRNAAKVLNYSRMYGAGIKSSTDTLLKYNPELKPQEAFNKIKDLMKQTKGKR-----SQGKWV----------------------------------------------DGIESEVFSKLEEIAKSDEPSTPVLNARLSQALEKRVVNEKFMTSKCNWVVQSSGVDYLHCLLTFTKHLIQLYNVNARLCICIHDEIRYLCEEKDKYRLALILQIANLYTRSVFSMKLNLFDLPQSIAFFSEIDIDYCLRKSPTDDCITPSNQNGLLNNYNIQKGESLNIYQILDKTGGRL 3380
G N VGSPFSK FL M+ G L + + +E K FWRN R+ SQ +V K E AI+PQV+ AGTVTRR+VE WLTA+N+ DRVGSELKAMVQ P + +VGADVDSQE WIAAVLG++ G+HG T FGWM LQG K GTDLHS+T+ +GISR AKV NY R+YGAG + L+++N L EA +K + + TKG R +G+W+ G ES++F+KLE IA+S +P+TPVL+ R+S+ALE + V +F+TS+ NWVVQSS VDYLH +L K L + +N++ R CI IHDE+RYL +D+YR AL LQI NL TRSVF+ L L DLPQS+AFFS +D+D CLRK DC+TPSN GL Y + GE+L+IYQI++ T G L
Sbjct: 682 GNHNNVGSPFSKDFLVKMEDGTLRAGRGGTNATLALEINKMMSFWRNAHKRISSQMVVWLRKGELPRNVSRHKDFDEEGQYGAILPQVVTAGTVTRRAVEPTWLTASNARRDRVGSELKAMVQVPPGYHLVGADVDSQELWIAAVLGEAHFAGMHGCTAFGWMTLQGKKSQGTDLHSRTADAVGISREHAKVFNYGRIYGAGQPFAERLLMQFNHRLNQMEAASKARQMYALTKGIRRYHLSEEGEWLVNELGIDVQREEDGSVSLQELRRISKVASHSSRRKKWDIVGKRVWAGGTESDMFNKLESIAQSAQPATPVLHCRISRALEPKAVRNEFITSRVNWVVQSSAVDYLHLMLVAMKWLFEEHNIDGRFCISIHDEVRYLVRSEDRYRAALALQITNLLTRSVFAHALGLQDLPQSVAFFSSVDVDQCLRKEVIMDCVTPSNPTGLERRYGLPPGEALDIYQIINITDGSL 1156 HSP 2 Score: 263.462 bits (672), Expect = 3.596e-72 Identity = 157/428 (36.68%), Postives = 239/428 (55.84%), Query Frame = 3
Query: 225 RINMMNIQMINKKFQETIFGS---KSTAELDFFEINSLFKNFKIDTEKTTLNKNVDFDLPPLLGENIEIHLQKAAETLNDPYMALLKGLDDWKIPQMPTMWSFQEGWTKYDTINNKFYKVSVPEENLLIFDVETLPKYTQRAVMAVAVGKSYWYSWTSKYLLDGICKDDSEICKDDLIPLYSNDDKSKP-------KCIVGHFVSFDRARIRDEYCIKGTGTRFIDTMSMQIAIRGMTSLQRSLKISFNNNNTENRIWKLYFSNSSKNGMNNSPEDIEESDKWLTEASLNSLVDVYQYYFPNCNLSSLKDKRETFIKGTIDDIVNDFQALMTYCATDVIMTAKIFQKLWTDYRVRFPHPASFTGMLEMGSLYLPVNSNLNTYINRASTTYESMIKKEKEILMELAQKSLA-SKEKEYINDPWLWDLDW 1475
R+N + IQM++K E IF + + E I L K+ ++ ++T+L +V+ LP + G+NI+ H + AE + PY+ + L ++P MP WS++ GWT+Y N KV P+E+ L+FDVE + +AVA+ + WYSW SK LL+ +++ +LIPL + + S+P + IVGH VSFDR+ I+++Y +KG+ RF+DTMS+ +AI G+T QR+L ++ N + R + + K G I D W+ +S+N+L DVY Y L K+ RE FIKG + D+ N+FQ LM YCA DV T ++F + + R PHP +F GMLEMG YLPVN N + Y+ Y+ + ++ K+ LM LA + ++ Y DPWLWDL+W
Sbjct: 42 RLNPLKIQMLSKNLHEQIFRGVVPEYSEEAVERSIKHLQKH-QLWGKETSLLPDVELKLPQMYGKNIDEHFRILAEKQSLPYLEAVTKLLQAELPSMPQEWSWEVGWTRYGP-NGGTQKVDFPDESALVFDVEVCMTEGRCPTLAVALSPTNWYSWCSKRLLEERYSWSNQLSLAELIPLETPLNSSRPPGGQWKERLIVGHNVSFDRSHIKEQYLLKGSIVRFLDTMSLHMAISGLTGFQRTLWMA--NKLGKKRGLQEVKEHIKKTGQKRDGPVIGSWD-WVNISSINNLADVYDLYVGGPPLQ--KEAREIFIKGNMTDVRNNFQELMQYCALDVEATHQVFTEQMPLFMERCPHPVTFAGMLEMGVSYLPVNQNWHRYLEDCQDVYDDLQREMKKSLMTLADDACQLLQDARYKEDPWLWDLEW 462 HSP 3 Score: 56.6102 bits (135), Expect = 1.700e-7 Identity = 24/60 (40.00%), Postives = 35/60 (58.33%), Query Frame = 3
Query: 1494 SFPKWFRVLVSKNENSNTFNP--DLITSQKSIAVKMLKLKWDGLPLHYDKKNKWGVLIPG 1667
P W+R L K + ++P LI+ Q + K++ L WDG PLHY +K+ WG L+PG
Sbjct: 536 GHPGWYRKLCEKMSQEDGWSPGASLISLQMRLTPKLMGLMWDGFPLHYTEKHGWGYLVPG 595
BLAST of DNA polymerase subunit gamma vs. Ensembl Medaka
Match: polg (DNA polymerase gamma, catalytic subunit [Source:NCBI gene;Acc:101156890]) HSP 1 Score: 413.305 bits (1061), Expect = 1.529e-124 Identity = 222/487 (45.59%), Postives = 285/487 (58.52%), Query Frame = 3
Query: 2118 IPFVWFLPLPHEKGEGNTVGSPFSKSFLNYMQSGRLTSHAANNLLEIMIEGKKSGVFWRNYQNRVQS-------QFMVRTSKENNE----SAIIPQVIVAGTVTRRSVERLWLTATNSTNDRVGSELKAMVQTPTNWVMVGADVDSQEQWIAAVLGDS-VTGIHGGTPFGWMVLQGSKVDGTDLHSKTSKMIGISRNAAKVLNYSRMYGAGIKSSTDTLLKYNPELKPQEAFNKIKDLMKQTKGKR-----SQGKWV----------------------------------------------DGIESEVFSKLEEIAKSDEPSTPVLNARLSQALEKRVVNEKFMTSKCNWVVQSSGVDYLHCLLTFTKHLIQLYNVNARLCICIHDEIRYLCEEKDKYRLALILQIANLYTRSVFSMKLNLFDLPQSIAFFSEIDIDYCLRKSPTDDCITPSNQNGLLNNYNIQKGE----------SLNIYQIL 3359
IP WF LPH+ G N VGSPFSK FL M+ G L + + +E K FWRN R++S F+ K+ +E AI+PQV+ AGTVTRR+VE WLTA+N+ DRVGSELKAMVQ P + +VGADVDSQE WIAAVLG++ G+HG T FGWM LQG K GTDLHS+T+ +GISR AKV NY R+YGAG + L+++N L EA +K + + TKG R +G+W+ G ES++F+KLE IA+S +P+TPVL+ R+S+ALE + V +F+TS+ NWVVQSS VDYLH +L K L + +N++ R CI IHDE+RYL +D+YR AL LQI NL TRSVF+ L L DLPQS+AFFS +D+D CLRK DC+TPSN GL Y + GE LN++ IL
Sbjct: 701 IPGCWFFKLPHKDGNHNNVGSPFSKDFLVKMEDGTLRAGRGGTNATLALEINKMMSFWRNAHKRIRSVTSTLPDDFVSHRHKDFDEEGQYGAILPQVVTAGTVTRRAVEPTWLTASNARRDRVGSELKAMVQVPPGYHLVGADVDSQELWIAAVLGEAHFAGMHGCTAFGWMTLQGKKSQGTDLHSRTADAVGISREHAKVFNYGRIYGAGQPFAERLLMQFNHRLNQMEAASKARQMYALTKGIRRYHLSEEGEWLVNELGIDVQREEDGSVSLQELRRISKVASHSSRRKKWDIVGKRVWAGGTESDMFNKLESIAQSAQPATPVLHCRISRALEPKAVRNEFITSRVNWVVQSSAVDYLHLMLVAMKWLFEEHNIDGRFCISIHDEVRYLVRSEDRYRAALALQITNLLTRSVFAHALGLQDLPQSVAFFSSVDVDQCLRKEVIMDCVTPSNPTGLERRYGLPPGEFWVLFFQSRAGLNLFAIL 1187 HSP 2 Score: 263.462 bits (672), Expect = 4.789e-72 Identity = 157/428 (36.68%), Postives = 239/428 (55.84%), Query Frame = 3
Query: 225 RINMMNIQMINKKFQETIFGS---KSTAELDFFEINSLFKNFKIDTEKTTLNKNVDFDLPPLLGENIEIHLQKAAETLNDPYMALLKGLDDWKIPQMPTMWSFQEGWTKYDTINNKFYKVSVPEENLLIFDVETLPKYTQRAVMAVAVGKSYWYSWTSKYLLDGICKDDSEICKDDLIPLYSNDDKSKP-------KCIVGHFVSFDRARIRDEYCIKGTGTRFIDTMSMQIAIRGMTSLQRSLKISFNNNNTENRIWKLYFSNSSKNGMNNSPEDIEESDKWLTEASLNSLVDVYQYYFPNCNLSSLKDKRETFIKGTIDDIVNDFQALMTYCATDVIMTAKIFQKLWTDYRVRFPHPASFTGMLEMGSLYLPVNSNLNTYINRASTTYESMIKKEKEILMELAQKSLA-SKEKEYINDPWLWDLDW 1475
R+N + IQM++K E IF + + E I L K+ ++ ++T+L +V+ LP + G+NI+ H + AE + PY+ + L ++P MP WS++ GWT+Y N KV P+E+ L+FDVE + +AVA+ + WYSW SK LL+ +++ +LIPL + + S+P + IVGH VSFDR+ I+++Y +KG+ RF+DTMS+ +AI G+T QR+L ++ N + R + + K G I D W+ +S+N+L DVY Y L K+ RE FIKG + D+ N+FQ LM YCA DV T ++F + + R PHP +F GMLEMG YLPVN N + Y+ Y+ + ++ K+ LM LA + ++ Y DPWLWDL+W
Sbjct: 53 RLNPLKIQMLSKNLHEQIFRGVVPEYSEEAVERSIKHLQKH-QLWGKETSLLPDVELKLPQMYGKNIDEHFRILAEKQSLPYLEAVTKLLQAELPSMPQEWSWEVGWTRYGP-NGGTQKVDFPDESALVFDVEVCMTEGRCPTLAVALSPTNWYSWCSKRLLEERYSWSNQLSLAELIPLETPLNSSRPPGGQWKERLIVGHNVSFDRSHIKEQYLLKGSIVRFLDTMSLHMAISGLTGFQRTLWMA--NKLGKKRGLQEVKEHIKKTGQKRDGPVIGSWD-WVNISSINNLADVYDLYVGGPPLQ--KEAREIFIKGNMTDVRNNFQELMQYCALDVEATHQVFTEQMPLFMERCPHPVTFAGMLEMGVSYLPVNQNWHRYLEDCQDVYDDLQREMKKSLMTLADDACQLLQDARYKEDPWLWDLEW 473 HSP 3 Score: 56.6102 bits (135), Expect = 1.946e-7 Identity = 24/60 (40.00%), Postives = 35/60 (58.33%), Query Frame = 3
Query: 1494 SFPKWFRVLVSKNENSNTFNP--DLITSQKSIAVKMLKLKWDGLPLHYDKKNKWGVLIPG 1667
P W+R L K + ++P LI+ Q + K++ L WDG PLHY +K+ WG L+PG
Sbjct: 547 GHPGWYRKLCEKMSQEDGWSPGASLISLQMRLTPKLMGLMWDGFPLHYTEKHGWGYLVPG 606
BLAST of DNA polymerase subunit gamma vs. Planmine SMEST
Match: SMESG000050799.1 (SMESG000050799.1) HSP 1 Score: 2227.59 bits (5771), Expect = 0.000e+0 Identity = 1076/1077 (99.91%), Postives = 1077/1077 (100.00%), Query Frame = 3
Query: 153 SGYLPKPSNFGRLLNTANSSDDKLRINMMNIQMINKKFQETIFGSKSTAELDFFEINSLFKNFKIDTEKTTLNKNVDFDLPPLLGENIEIHLQKAAETLNDPYMALLKGLDDWKIPQMPTMWSFQEGWTKYDTINNKFYKVSVPEENLLIFDVETLPKYTQRAVMAVAVGKSYWYSWTSKYLLDGICKDDSEICKDDLIPLYSNDDKSKPKCIVGHFVSFDRARIRDEYCIKGTGTRFIDTMSMQIAIRGMTSLQRSLKISFNNNNTENRIWKLYFSNSSKNGMNNSPEDIEESDKWLTEASLNSLVDVYQYYFPNCNLSSLKDKRETFIKGTIDDIVNDFQALMTYCATDVIMTAKIFQKLWTDYRVRFPHPASFTGMLEMGSLYLPVNSNLNTYINRASTTYESMIKKEKEILMELAQKSLASKEKEYINDPWLWDLDWSTTKKSSFPKWFRVLVSKNENSNTFNPDLITSQKSIAVKMLKLKWDGLPLHYDKKNKWGVLIPGCYLPVWYDEKFMDISNKLIWPIIPVERISPSYIDYFQFPLQKYVQFWVPLFVSRLEAFRDFLLSLGNSDLTKYNVFVEYMMAIVEPINFTPENLTKVNSLLCEIKEITLRNSKGYYNSNEEGPLSLYNFQMNDFSSLFAKTKCLLTENPIIPFVWFLPLPHEKGEGNTVGSPFSKSFLNYMQSGRLTSHAANNLLEIMIEGKKSGVFWRNYQNRVQSQFMVRTSKENNESAIIPQVIVAGTVTRRSVERLWLTATNSTNDRVGSELKAMVQTPTNWVMVGADVDSQEQWIAAVLGDSVTGIHGGTPFGWMVLQGSKVDGTDLHSKTSKMIGISRNAAKVLNYSRMYGAGIKSSTDTLLKYNPELKPQEAFNKIKDLMKQTKGKRSQGKWVDGIESEVFSKLEEIAKSDEPSTPVLNARLSQALEKRVVNEKFMTSKCNWVVQSSGVDYLHCLLTFTKHLIQLYNVNARLCICIHDEIRYLCEEKDKYRLALILQIANLYTRSVFSMKLNLFDLPQSIAFFSEIDIDYCLRKSPTDDCITPSNQNGLLNNYNIQKGESLNIYQILDKTGGRLD 3383
+GYLPKPSNFGRLLNTANSSDDKLRINMMNIQMINKKFQETIFGSKSTAELDFFEINSLFKNFKIDTEKTTLNKNVDFDLPPLLGENIEIHLQKAAETLNDPYMALLKGLDDWKIPQMPTMWSFQEGWTKYDTINNKFYKVSVPEENLLIFDVETLPKYTQRAVMAVAVGKSYWYSWTSKYLLDGICKDDSEICKDDLIPLYSNDDKSKPKCIVGHFVSFDRARIRDEYCIKGTGTRFIDTMSMQIAIRGMTSLQRSLKISFNNNNTENRIWKLYFSNSSKNGMNNSPEDIEESDKWLTEASLNSLVDVYQYYFPNCNLSSLKDKRETFIKGTIDDIVNDFQALMTYCATDVIMTAKIFQKLWTDYRVRFPHPASFTGMLEMGSLYLPVNSNLNTYINRASTTYESMIKKEKEILMELAQKSLASKEKEYINDPWLWDLDWSTTKKSSFPKWFRVLVSKNENSNTFNPDLITSQKSIAVKMLKLKWDGLPLHYDKKNKWGVLIPGCYLPVWYDEKFMDISNKLIWPIIPVERISPSYIDYFQFPLQKYVQFWVPLFVSRLEAFRDFLLSLGNSDLTKYNVFVEYMMAIVEPINFTPENLTKVNSLLCEIKEITLRNSKGYYNSNEEGPLSLYNFQMNDFSSLFAKTKCLLTENPIIPFVWFLPLPHEKGEGNTVGSPFSKSFLNYMQSGRLTSHAANNLLEIMIEGKKSGVFWRNYQNRVQSQFMVRTSKENNESAIIPQVIVAGTVTRRSVERLWLTATNSTNDRVGSELKAMVQTPTNWVMVGADVDSQEQWIAAVLGDSVTGIHGGTPFGWMVLQGSKVDGTDLHSKTSKMIGISRNAAKVLNYSRMYGAGIKSSTDTLLKYNPELKPQEAFNKIKDLMKQTKGKRSQGKWVDGIESEVFSKLEEIAKSDEPSTPVLNARLSQALEKRVVNEKFMTSKCNWVVQSSGVDYLHCLLTFTKHLIQLYNVNARLCICIHDEIRYLCEEKDKYRLALILQIANLYTRSVFSMKLNLFDLPQSIAFFSEIDIDYCLRKSPTDDCITPSNQNGLLNNYNIQKGESLNIYQILDKTGGRLD
Sbjct: 9 NGYLPKPSNFGRLLNTANSSDDKLRINMMNIQMINKKFQETIFGSKSTAELDFFEINSLFKNFKIDTEKTTLNKNVDFDLPPLLGENIEIHLQKAAETLNDPYMALLKGLDDWKIPQMPTMWSFQEGWTKYDTINNKFYKVSVPEENLLIFDVETLPKYTQRAVMAVAVGKSYWYSWTSKYLLDGICKDDSEICKDDLIPLYSNDDKSKPKCIVGHFVSFDRARIRDEYCIKGTGTRFIDTMSMQIAIRGMTSLQRSLKISFNNNNTENRIWKLYFSNSSKNGMNNSPEDIEESDKWLTEASLNSLVDVYQYYFPNCNLSSLKDKRETFIKGTIDDIVNDFQALMTYCATDVIMTAKIFQKLWTDYRVRFPHPASFTGMLEMGSLYLPVNSNLNTYINRASTTYESMIKKEKEILMELAQKSLASKEKEYINDPWLWDLDWSTTKKSSFPKWFRVLVSKNENSNTFNPDLITSQKSIAVKMLKLKWDGLPLHYDKKNKWGVLIPGCYLPVWYDEKFMDISNKLIWPIIPVERISPSYIDYFQFPLQKYVQFWVPLFVSRLEAFRDFLLSLGNSDLTKYNVFVEYMMAIVEPINFTPENLTKVNSLLCEIKEITLRNSKGYYNSNEEGPLSLYNFQMNDFSSLFAKTKCLLTENPIIPFVWFLPLPHEKGEGNTVGSPFSKSFLNYMQSGRLTSHAANNLLEIMIEGKKSGVFWRNYQNRVQSQFMVRTSKENNESAIIPQVIVAGTVTRRSVERLWLTATNSTNDRVGSELKAMVQTPTNWVMVGADVDSQEQWIAAVLGDSVTGIHGGTPFGWMVLQGSKVDGTDLHSKTSKMIGISRNAAKVLNYSRMYGAGIKSSTDTLLKYNPELKPQEAFNKIKDLMKQTKGKRSQGKWVDGIESEVFSKLEEIAKSDEPSTPVLNARLSQALEKRVVNEKFMTSKCNWVVQSSGVDYLHCLLTFTKHLIQLYNVNARLCICIHDEIRYLCEEKDKYRLALILQIANLYTRSVFSMKLNLFDLPQSIAFFSEIDIDYCLRKSPTDDCITPSNQNGLLNNYNIQKGESLNIYQILDKTGGRLD 1085
BLAST of DNA polymerase subunit gamma vs. Planmine SMEST
Match: SMESG000050769.1 (SMESG000050769.1) HSP 1 Score: 309.301 bits (791), Expect = 2.714e-90 Identity = 167/395 (42.28%), Postives = 235/395 (59.49%), Query Frame = 3
Query: 504 MPTMWSFQEGWTKYDTINNKFYKVSVPEENLLIFDVETLPKYTQRAVMAVAVGKSYWYSWTSKYLLDGICKDDSEICKDDLIPLYSNDDKSKPKCIVGHFVSFDRARIRDEYCIKGTGTRFIDTMSMQIAIRGMT-SLQRSLKISFNNNNTENRIWKLYFSNSSKNGMNNSPEDIEESDKWLTEASLNSLVDVYQYYFPNCNLSSLKDKRETFIKGTIDDIVNDFQALMTYCATDVIMTAKIFQKLWTDYRVRFPHPASFTGMLEMGSLYLPVNSNLNTYINRASTTYESM-IKKEKEILMELAQKSLA-SKEKEYINDPWLWDLDWSTTKKSSFPKWFRVLVSKNENSNTFNPDLITSQKSIAVKMLKLKWDGLPLHYDKKNKWGVLIPGCYLP 1679
MP + + EGWTKYD N F KV P+E ++IFD+E + +AV +G+ WYSW S L+ + + D+LI L+ N D++ +C++GHFVS+DRAR+ +EY + + TR++DTMSM IAI GMT SL++ K S E KW T S N L+DVY YFPN KDKR F+ G+ D++N+FQALM YCA DV+MTA+IFQKL+ ++ RFPH + GMLE+ SLYLP N+ +I +++ + ++ +K IL + A LA K+ Y DPWLWDL W+ P+W++ L+ K +++N+ P L+TS IAVK+L+L+WDGLPL+YDKK KWGVL P C +P
Sbjct: 1 MPEKFCYCEGWTKYDKKANSFSKVPFPDEKVMIFDIEVIVNEGNWPSIAVCLGQDSWYSWVSNRLIKSNNTNRDIVYSDELIELFDNKDRNIFRCVIGHFVSYDRARVANEYVNQSSNTRYVDTMSMHIAISGMTASLRQRYKTS-------------------------------EKFKWKTVTSGNGLLDVYSLYFPNKEPPQNKDKRNIFVTGSSTDVINNFQALMKYCANDVLMTAEIFQKLFPIFQKRFPHKSVLYGMLELNSLYLPTNNKWFQFIEQSNKDFYTIGSNHQKIILKKAANIGLALGKDDNYKKDPWLWDLKWT----KPLPRWYKDLIPK-DSANSCEPSLLTSSMGIAVKLLRLRWDGLPLYYDKKYKWGVLKP-CKMP 358 HSP 2 Score: 170.244 bits (430), Expect = 3.795e-43 Identity = 121/410 (29.51%), Postives = 208/410 (50.73%), Query Frame = 3
Query: 2133 FLPLPHEKGEGNTVGSPFSKSFLNYMQSGRLTSHAANNLLEIMIEGKKSGVFWRNYQNRVQSQFMVRTSKEN--NESAIIPQVIVAGTVTRRSVERLWLTATNSTNDRVGSELKAMVQTPTNWVMVGADVDSQEQWIAAVLGDSVTGIHGGTPFGWMVLQGSKVD----GTDLHSKTSKMIGISRNAAKVLNYSRMYGAGIKSSTDTLLKYNPELKPQEAFNKIKDLMKQTKGKRSQGKWVDGIESEVFSKLEEIAKSDEPSTPVLNARLSQALEKRVVNEKFMTSKCNWVVQSSGVDYLHCLLTFTKHLIQLYNVNARLCICIHDEIRYLCEEKDKYRLALILQIANLYTRSVFSMKLNLFDLPQSIAFFSEIDIDYCLRKSPTDDCITPSNQNGLLNNYNIQKGESLN 3344
F P+ H+ G V S ++ + RLTS+ ++ + ++ S +FW++ N +++Q +V+ ++ + NE AIIP VI R+ +LW TN ++G E K+M+ P ++V VG + + WI + DS+ G G + FG VL + T L+S + M I +N + L +YG G K L N +A + KGK+ + W +G+ S+ F+ + + KS + TP L+++ S+ L +++ +C ++SS DY+ CL+ + K LI +N+RL IC +EIR+LC E D+Y++A L A+ T+ F+ L+L ++P F +DID C R +P +D + + + G+ NY I+ G SL+
Sbjct: 394 FKPMVHKDGFDKYVSRVLSDDSISNLALNRLTSNL--DIGKEFLQSIGSCLFWKSSGNLIKNQMIVKLNRNSTSNEMAIIPPVIPISNPYRKIDAKLWFDNFYLTN-QIGVEYKSMIMAPQHYVFVGHTLHNIVDWIIGICCDSIHGELGASQFGKEVLNAGLNNLMGFNTTLYSNLANMTNIDKNIFRRLALILIYG-GNKEDIVHFLWKNVSYNMIDAKKYADKYYLKLKGKKIERIWQNGVLSDFFNVMYNVIKSKDLKTPFLSSKFSKPL---IISGNRELMQC--FLKSSVSDYICCLIVYAKALIVEMKLNSRLSICNKNEIRFLCHENDRYKMAYALHCADSATKIAFASFLSLRNVPSEFRFLDSVDIDECWRMNPMNDFCSETGR-GIYYNYGIKPGFSLH 793
BLAST of DNA polymerase subunit gamma vs. Planmine SMEST
Match: SMESG000050769.1 (SMESG000050769.1) HSP 1 Score: 303.523 bits (776), Expect = 3.516e-88 Identity = 167/399 (41.85%), Postives = 235/399 (58.90%), Query Frame = 3
Query: 504 MPTMWSFQEGWTKYDTINNKFYKVSVPEENLLIFDVETLPKYTQRAVMAVAVGKSYWYSWTSKYLLDGICKDDSEICKDDLIPLYSNDDKSKPKCIVGHFVSFDRARIRDEYCIK----GTGTRFIDTMSMQIAIRGMT-SLQRSLKISFNNNNTENRIWKLYFSNSSKNGMNNSPEDIEESDKWLTEASLNSLVDVYQYYFPNCNLSSLKDKRETFIKGTIDDIVNDFQALMTYCATDVIMTAKIFQKLWTDYRVRFPHPASFTGMLEMGSLYLPVNSNLNTYINRASTTYESM-IKKEKEILMELAQKSLA-SKEKEYINDPWLWDLDWSTTKKSSFPKWFRVLVSKNENSNTFNPDLITSQKSIAVKMLKLKWDGLPLHYDKKNKWGVLIPGCYLP 1679
MP + + EGWTKYD N F KV P+E ++IFD+E + +AV +G+ WYSW S L+ + + D+LI L+ N D++ +C++GHFVS+DRAR+ +EY + + TR++DTMSM IAI GMT SL++ K S E KW T S N L+DVY YFPN KDKR F+ G+ D++N+FQALM YCA DV+MTA+IFQKL+ ++ RFPH + GMLE+ SLYLP N+ +I +++ + ++ +K IL + A LA K+ Y DPWLWDL W+ P+W++ L+ K +++N+ P L+TS IAVK+L+L+WDGLPL+YDKK KWGVL P C +P
Sbjct: 1 MPEKFCYCEGWTKYDKKANSFSKVPFPDEKVMIFDIEVIVNEGNWPSIAVCLGQDSWYSWVSNRLIKSNNTNRDIVYSDELIELFDNKDRNIFRCVIGHFVSYDRARVANEYVNQWLDESSNTRYVDTMSMHIAISGMTASLRQRYKTS-------------------------------EKFKWKTVTSGNGLLDVYSLYFPNKEPPQNKDKRNIFVTGSSTDVINNFQALMKYCANDVLMTAEIFQKLFPIFQKRFPHKSVLYGMLELNSLYLPTNNKWFQFIEQSNKDFYTIGSNHQKIILKKAANIGLALGKDDNYKKDPWLWDLKWT----KPLPRWYKDLIPK-DSANSCEPSLLTSSMGIAVKLLRLRWDGLPLYYDKKYKWGVLKP-CKMP 362 HSP 2 Score: 170.629 bits (431), Expect = 3.536e-43 Identity = 121/410 (29.51%), Postives = 208/410 (50.73%), Query Frame = 3
Query: 2133 FLPLPHEKGEGNTVGSPFSKSFLNYMQSGRLTSHAANNLLEIMIEGKKSGVFWRNYQNRVQSQFMVRTSKEN--NESAIIPQVIVAGTVTRRSVERLWLTATNSTNDRVGSELKAMVQTPTNWVMVGADVDSQEQWIAAVLGDSVTGIHGGTPFGWMVLQGSKVD----GTDLHSKTSKMIGISRNAAKVLNYSRMYGAGIKSSTDTLLKYNPELKPQEAFNKIKDLMKQTKGKRSQGKWVDGIESEVFSKLEEIAKSDEPSTPVLNARLSQALEKRVVNEKFMTSKCNWVVQSSGVDYLHCLLTFTKHLIQLYNVNARLCICIHDEIRYLCEEKDKYRLALILQIANLYTRSVFSMKLNLFDLPQSIAFFSEIDIDYCLRKSPTDDCITPSNQNGLLNNYNIQKGESLN 3344
F P+ H+ G V S ++ + RLTS+ ++ + ++ S +FW++ N +++Q +V+ ++ + NE AIIP VI R+ +LW TN ++G E K+M+ P ++V VG + + WI + DS+ G G + FG VL + T L+S + M I +N + L +YG G K L N +A + KGK+ + W +G+ S+ F+ + + KS + TP L+++ S+ L +++ +C ++SS DY+ CL+ + K LI +N+RL IC +EIR+LC E D+Y++A L A+ T+ F+ L+L ++P F +DID C R +P +D + + + G+ NY I+ G SL+
Sbjct: 398 FKPMVHKDGFDKYVSRVLSDDSISNLALNRLTSNL--DIGKEFLQSIGSCLFWKSSGNLIKNQMIVKLNRNSTSNEMAIIPPVIPISNPYRKIDAKLWFDNFYLTN-QIGVEYKSMIMAPQHYVFVGHTLHNIVDWIIGICCDSIHGELGASQFGKEVLNAGLNNLMGFNTTLYSNLANMTNIDKNIFRRLALILIYG-GNKEDIVHFLWKNVSYNMIDAKKYADKYYLKLKGKKIERIWQNGVLSDFFNVMYNVIKSKDLKTPFLSSKFSKPL---IISGNRELMQC--FLKSSVSDYICCLIVYAKALIVEMKLNSRLSICNKNEIRFLCHENDRYKMAYALHCADSATKIAFASFLSLRNVPSEFRFLDSVDIDECWRMNPMNDFCSETGR-GIYYNYGIKPGFSLH 797 The following BLAST results are available for this feature:
BLAST of DNA polymerase subunit gamma vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of DNA polymerase subunit gamma vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 1
BLAST of DNA polymerase subunit gamma vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 1
BLAST of DNA polymerase subunit gamma vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 1
BLAST of DNA polymerase subunit gamma vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of DNA polymerase subunit gamma vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of DNA polymerase subunit gamma vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of DNA polymerase subunit gamma vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of DNA polymerase subunit gamma vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 4
BLAST of DNA polymerase subunit gamma vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 1
BLAST of DNA polymerase subunit gamma vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 1
BLAST of DNA polymerase subunit gamma vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 1
BLAST of DNA polymerase subunit gamma vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of DNA polymerase subunit gamma vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 3
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30020035 ID=SMED30020035|Name=DNA polymerase subunit gamma|organism=Schmidtea mediterranea sexual|type=transcript|length=3490bpback to top protein sequence of SMED30020035-orf-1 >SMED30020035-orf-1 ID=SMED30020035-orf-1|Name=SMED30020035-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1051bp MMNIQMINKKFQETIFGSKSTAELDFFEINSLFKNFKIDTEKTTLNKNVDback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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