Sm domain-containing protein

Overview
NameSm domain-containing protein
Smed IDSMED30019973
Length (bp)473
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Sm domain-containing protein (SMED30019973) t-SNE clustered cells

Violin plots show distribution of expression levels for Sm domain-containing protein (SMED30019973) in cells (dots) of each of the 12 neoblast clusters.

 

back to top


 

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Sm domain-containing protein (SMED30019973) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Sm domain-containing protein (SMED30019973) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

back to top


 

Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

back to top
Anatomical Expression

PAGE et. al., 2020




SMED30019973

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 3

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30019973 SmedASXL_003253SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015
FACS sorted cell population asexual adult RNA-sequencing evidence
posterior sideSMED30019973 dd_Smed_v4_3610_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
posterior muscle cellSMED30019973 dd_Smed_v4_3610_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Sm domain-containing protein vs. Ensembl Human
Match: LSM7 (LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated [Source:HGNC Symbol;Acc:HGNC:20470])

HSP 1 Score: 139.043 bits (349), Expect = 6.967e-43
Identity = 66/94 (70.21%), Postives = 78/94 (82.98%), Query Frame = 3
Query:  150 EKKRKETIIDLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTRDLGLVVCKGPTVEVIFPSDGMEPISNPFV 431
            EKK+KE+I+DLS YIDK IRVKF GGRE SGILKG DPLLN+VLD T EY+RDP+D  K+TE+TR LGLVVC+G +V +I P DGME I NPF+
Sbjct:    5 EKKKKESILDLSKYIDKTIRVKFQGGREASGILKGFDPLLNLVLDGTIEYMRDPDDQYKLTEDTRQLGLVVCRGTSVVLICPQDGMEAIPNPFI 98          
BLAST of Sm domain-containing protein vs. Ensembl Human
Match: LSM7 (LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated [Source:HGNC Symbol;Acc:HGNC:20470])

HSP 1 Score: 63.5438 bits (153), Expect = 6.770e-14
Identity = 27/44 (61.36%), Postives = 35/44 (79.55%), Query Frame = 3
Query:  300 LRDPEDATKITENTRDLGLVVCKGPTVEVIFPSDGMEPISNPFV 431
            +RDP+D  K+TE+TR LGLVVC+G +V +I P DGME I NPF+
Sbjct:    1 MRDPDDQYKLTEDTRQLGLVVCRGTSVVLICPQDGMEAIPNPFI 44          
BLAST of Sm domain-containing protein vs. Ensembl Human
Match: LSM7 (LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated [Source:HGNC Symbol;Acc:HGNC:20470])

HSP 1 Score: 49.6766 bits (117), Expect = 2.173e-8
Identity = 24/33 (72.73%), Postives = 27/33 (81.82%), Query Frame = 3
Query:  150 EKKRKETIIDLSIYIDKRIRVKFAGGREVSGIL 248
            EKK+KE+I+DLS YIDK IRVKF GGRE S  L
Sbjct:    3 EKKKKESILDLSKYIDKTIRVKFQGGREESQAL 35          
BLAST of Sm domain-containing protein vs. Ensembl Human
Match: LSM7 (LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated [Source:HGNC Symbol;Acc:HGNC:20470])

HSP 1 Score: 48.521 bits (114), Expect = 3.599e-8
Identity = 23/29 (79.31%), Postives = 26/29 (89.66%), Query Frame = 3
Query:  150 EKKRKETIIDLSIYIDKRIRVKFAGGREV 236
            EKK+KE+I+DLS YIDK IRVKF GGREV
Sbjct:    5 EKKKKESILDLSKYIDKTIRVKFQGGREV 33          
BLAST of Sm domain-containing protein vs. Ensembl Human
Match: SNRPG (small nuclear ribonucleoprotein polypeptide G [Source:HGNC Symbol;Acc:HGNC:11163])

HSP 1 Score: 48.521 bits (114), Expect = 6.083e-8
Identity = 24/67 (35.82%), Postives = 42/67 (62.69%), Query Frame = 3
Query:  180 LSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTRDLGLVVCKGPTV 380
            + +++DK++ +K  GGR V GIL+G DP +N+V+D   E       AT   +N  ++G+VV +G ++
Sbjct:    1 MCLFMDKKLSLKLNGGRHVQGILRGFDPFMNLVIDECVEM------ATSGQQN--NIGMVVIRGNSI 59          
BLAST of Sm domain-containing protein vs. Ensembl Celegans
Match: lsm-7 (LSM Sm-like protein [Source:UniProtKB/TrEMBL;Acc:Q23543])

HSP 1 Score: 116.316 bits (290), Expect = 2.653e-34
Identity = 50/93 (53.76%), Postives = 72/93 (77.42%), Query Frame = 3
Query:  153 KKRKETIIDLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTRDLGLVVCKGPTVEVIFPSDGMEPISNPFV 431
            K++KE+++DL+ ++DK IRVKF GGRE SG+L+G D LLNMVLD   EYLRDP++ + + + TR LGL+V +G  + V+ P+DG+E I+NPF 
Sbjct:    7 KRKKESVVDLTRFLDKEIRVKFQGGREASGVLRGFDQLLNMVLDDCREYLRDPQNPSVVGDETRQLGLIVARGTAITVVSPADGLEQIANPFA 99          
BLAST of Sm domain-containing protein vs. Ensembl Celegans
Match: snr-7 (Probable small nuclear ribonucleoprotein G [Source:UniProtKB/Swiss-Prot;Acc:Q9N4G9])

HSP 1 Score: 55.0694 bits (131), Expect = 8.774e-11
Identity = 28/75 (37.33%), Postives = 44/75 (58.67%), Query Frame = 3
Query:  177 DLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTRDLGLVVCKGPTVEVIFPSD 401
            +L  Y+DK + +K  G R VSGIL+G DP +NMV+D   EY +D          + +LG+ V +G +V ++ P +
Sbjct:    8 ELKKYMDKEMDLKLNGNRRVSGILRGFDPFMNMVIDEAVEYQKD--------GGSVNLGMTVIRGNSVVIMEPKE 74          
BLAST of Sm domain-containing protein vs. Ensembl Fly
Match: LSm7 (gene:FBgn0261068 transcript:FBtr0343770)

HSP 1 Score: 126.331 bits (316), Expect = 4.450e-38
Identity = 61/95 (64.21%), Postives = 77/95 (81.05%), Query Frame = 3
Query:  150 EKKRKETIIDLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKIT-ENTRDLGLVVCKGPTVEVIFPSDGMEPISNPFV 431
            EK+RKE+I+DLS Y++K+IRVKFAGGRE SGILKG D LLN+VLD T EYLRD ++  K+T E TR LGLVVC+G  + +I P DG+E I+NPF+
Sbjct:   14 EKRRKESILDLSKYLEKQIRVKFAGGREASGILKGYDALLNLVLDNTVEYLRDSDEPYKLTEEQTRSLGLVVCRGTALVLICPQDGVESIANPFI 108          
BLAST of Sm domain-containing protein vs. Ensembl Fly
Match: LSm7 (gene:FBgn0261068 transcript:FBtr0080934)

HSP 1 Score: 126.331 bits (316), Expect = 4.450e-38
Identity = 61/95 (64.21%), Postives = 77/95 (81.05%), Query Frame = 3
Query:  150 EKKRKETIIDLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKIT-ENTRDLGLVVCKGPTVEVIFPSDGMEPISNPFV 431
            EK+RKE+I+DLS Y++K+IRVKFAGGRE SGILKG D LLN+VLD T EYLRD ++  K+T E TR LGLVVC+G  + +I P DG+E I+NPF+
Sbjct:   14 EKRRKESILDLSKYLEKQIRVKFAGGREASGILKGYDALLNLVLDNTVEYLRDSDEPYKLTEEQTRSLGLVVCRGTALVLICPQDGVESIANPFI 108          
BLAST of Sm domain-containing protein vs. Ensembl Fly
Match: LSm7 (gene:FBgn0261068 transcript:FBtr0308804)

HSP 1 Score: 126.331 bits (316), Expect = 4.450e-38
Identity = 61/95 (64.21%), Postives = 77/95 (81.05%), Query Frame = 3
Query:  150 EKKRKETIIDLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKIT-ENTRDLGLVVCKGPTVEVIFPSDGMEPISNPFV 431
            EK+RKE+I+DLS Y++K+IRVKFAGGRE SGILKG D LLN+VLD T EYLRD ++  K+T E TR LGLVVC+G  + +I P DG+E I+NPF+
Sbjct:   14 EKRRKESILDLSKYLEKQIRVKFAGGREASGILKGYDALLNLVLDNTVEYLRDSDEPYKLTEEQTRSLGLVVCRGTALVLICPQDGVESIANPFI 108          
BLAST of Sm domain-containing protein vs. Ensembl Fly
Match: SNRPG (gene:FBgn0261791 transcript:FBtr0112993)

HSP 1 Score: 53.5286 bits (127), Expect = 5.516e-10
Identity = 28/68 (41.18%), Postives = 45/68 (66.18%), Query Frame = 3
Query:  189 YIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTR-DLGLVVCKGPTVEVI 389
            Y+DKR+ +K  GGR V+GIL+G DP +N+VLD T E  +D         NT+ ++G+VV +G ++ ++
Sbjct:   12 YMDKRMMLKLNGGRAVTGILRGFDPFMNVVLDDTVEECKD---------NTKNNIGMVVIRGNSIVMV 70          
BLAST of Sm domain-containing protein vs. Ensembl Fly
Match: SNRPG (gene:FBgn0261791 transcript:FBtr0074377)

HSP 1 Score: 53.5286 bits (127), Expect = 5.516e-10
Identity = 28/68 (41.18%), Postives = 45/68 (66.18%), Query Frame = 3
Query:  189 YIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTR-DLGLVVCKGPTVEVI 389
            Y+DKR+ +K  GGR V+GIL+G DP +N+VLD T E  +D         NT+ ++G+VV +G ++ ++
Sbjct:   12 YMDKRMMLKLNGGRAVTGILRGFDPFMNVVLDDTVEECKD---------NTKNNIGMVVIRGNSIVMV 70          
BLAST of Sm domain-containing protein vs. Ensembl Zebrafish
Match: lsm7 (LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated [Source:ZFIN;Acc:ZDB-GENE-030131-8284])

HSP 1 Score: 136.732 bits (343), Expect = 3.614e-42
Identity = 64/94 (68.09%), Postives = 77/94 (81.91%), Query Frame = 3
Query:  150 EKKRKETIIDLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTRDLGLVVCKGPTVEVIFPSDGMEPISNPFV 431
            +KK+KE+I DLS YIDK IRVKF GGRE SG+LKG DPLLN+VLD T EY+RDP+D  K+TE+TR LGLVVC+G +V +I P DGME I NPF+
Sbjct:    5 DKKKKESIFDLSKYIDKHIRVKFQGGREASGVLKGFDPLLNLVLDGTIEYMRDPDDQYKLTEDTRQLGLVVCRGTSVVLICPQDGMEAIPNPFI 98          
BLAST of Sm domain-containing protein vs. Ensembl Zebrafish
Match: lsm7 (LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated [Source:ZFIN;Acc:ZDB-GENE-030131-8284])

HSP 1 Score: 63.5438 bits (153), Expect = 4.082e-14
Identity = 27/44 (61.36%), Postives = 35/44 (79.55%), Query Frame = 3
Query:  300 LRDPEDATKITENTRDLGLVVCKGPTVEVIFPSDGMEPISNPFV 431
            +RDP+D  K+TE+TR LGLVVC+G +V +I P DGME I NPF+
Sbjct:    1 MRDPDDQYKLTEDTRQLGLVVCRGTSVVLICPQDGMEAIPNPFI 44          
BLAST of Sm domain-containing protein vs. Ensembl Zebrafish
Match: snrpg (small nuclear ribonucleoprotein polypeptide G [Source:ZFIN;Acc:ZDB-GENE-040912-105])

HSP 1 Score: 47.3654 bits (111), Expect = 1.495e-7
Identity = 26/68 (38.24%), Postives = 41/68 (60.29%), Query Frame = 3
Query:  177 DLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTRDLGLVVCKGPTV 380
            +L  ++DK++ +K  GGR V GIL+G DP +N+V+D T E       A     NT  +G+VV +G ++
Sbjct:    8 ELKKFMDKKLSLKLNGGRHVQGILRGFDPFMNLVVDDTIEM------APGGQMNT--IGMVVIRGNSI 67          
BLAST of Sm domain-containing protein vs. Ensembl Xenopus
Match: lsm7 (LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated [Source:NCBI gene;Acc:100127774])

HSP 1 Score: 139.043 bits (349), Expect = 6.315e-43
Identity = 66/94 (70.21%), Postives = 78/94 (82.98%), Query Frame = 3
Query:  150 EKKRKETIIDLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTRDLGLVVCKGPTVEVIFPSDGMEPISNPFV 431
            EKK+KE+I+DLS YIDK IRVKF GGRE SG+LKG DPLLN+VLD T EY+RDP+D  K+TE+TR LGLVVC+G +V +I P DGME I NPFV
Sbjct:    5 EKKKKESILDLSKYIDKAIRVKFQGGREASGVLKGFDPLLNLVLDGTIEYMRDPDDQYKLTEDTRQLGLVVCRGTSVVLICPQDGMEAIPNPFV 98          
BLAST of Sm domain-containing protein vs. Ensembl Xenopus
Match: lsm7 (LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated [Source:NCBI gene;Acc:100127774])

HSP 1 Score: 139.043 bits (349), Expect = 6.817e-43
Identity = 66/94 (70.21%), Postives = 78/94 (82.98%), Query Frame = 3
Query:  150 EKKRKETIIDLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTRDLGLVVCKGPTVEVIFPSDGMEPISNPFV 431
            EKK+KE+I+DLS YIDK IRVKF GGRE SG+LKG DPLLN+VLD T EY+RDP+D  K+TE+TR LGLVVC+G +V +I P DGME I NPFV
Sbjct:    5 EKKKKESILDLSKYIDKAIRVKFQGGREASGVLKGFDPLLNLVLDGTIEYMRDPDDQYKLTEDTRQLGLVVCRGTSVVLICPQDGMEAIPNPFV 98          
BLAST of Sm domain-containing protein vs. Ensembl Xenopus
Match: lsm7 (LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated [Source:NCBI gene;Acc:100127774])

HSP 1 Score: 64.3142 bits (155), Expect = 2.923e-14
Identity = 28/44 (63.64%), Postives = 35/44 (79.55%), Query Frame = 3
Query:  300 LRDPEDATKITENTRDLGLVVCKGPTVEVIFPSDGMEPISNPFV 431
            +RDP+D  K+TE+TR LGLVVC+G +V +I P DGME I NPFV
Sbjct:    1 MRDPDDQYKLTEDTRQLGLVVCRGTSVVLICPQDGMEAIPNPFV 44          
BLAST of Sm domain-containing protein vs. Ensembl Xenopus
Match: snrpg (small nuclear ribonucleoprotein polypeptide G [Source:NCBI gene;Acc:100125174])

HSP 1 Score: 47.3654 bits (111), Expect = 2.198e-7
Identity = 25/68 (36.76%), Postives = 42/68 (61.76%), Query Frame = 3
Query:  177 DLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTRDLGLVVCKGPTV 380
            +L  ++DK++ +K  GGR V GIL+G DP +N+V+D  TE       +    +NT  +G+VV +G ++
Sbjct:    8 ELKKFMDKKLSLKLNGGRHVQGILRGFDPFMNLVIDECTEI------SGGGHQNT--IGMVVIRGNSI 67          
BLAST of Sm domain-containing protein vs. Ensembl Mouse
Match: Lsm7 (LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated [Source:MGI Symbol;Acc:MGI:1913344])

HSP 1 Score: 139.813 bits (351), Expect = 2.593e-43
Identity = 67/94 (71.28%), Postives = 78/94 (82.98%), Query Frame = 3
Query:  150 EKKRKETIIDLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTRDLGLVVCKGPTVEVIFPSDGMEPISNPFV 431
            EKK+KE+I+DLS YIDK IRVKF GGRE SGILKG DPLLN+VLD T EY+RDP+D  K+TE+TR LGLVVC+G +V +I P DGME I NPFV
Sbjct:    5 EKKKKESILDLSKYIDKTIRVKFQGGREASGILKGFDPLLNLVLDGTMEYMRDPDDQYKLTEDTRQLGLVVCRGTSVVLICPQDGMEAIPNPFV 98          
BLAST of Sm domain-containing protein vs. Ensembl Mouse
Match: Lsm7 (LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated [Source:MGI Symbol;Acc:MGI:1913344])

HSP 1 Score: 83.1889 bits (204), Expect = 2.241e-21
Identity = 40/52 (76.92%), Postives = 45/52 (86.54%), Query Frame = 3
Query:  150 EKKRKETIIDLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLR 305
            EKK+KE+I+DLS YIDK IRVKF GGRE SGILKG DPLLN+VLD T EY+R
Sbjct:    5 EKKKKESILDLSKYIDKTIRVKFQGGREASGILKGFDPLLNLVLDGTMEYMR 56          
BLAST of Sm domain-containing protein vs. Ensembl Mouse
Match: Snrpg (small nuclear ribonucleoprotein polypeptide G [Source:MGI Symbol;Acc:MGI:1915261])

HSP 1 Score: 48.521 bits (114), Expect = 4.868e-8
Identity = 25/68 (36.76%), Postives = 42/68 (61.76%), Query Frame = 3
Query:  177 DLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTRDLGLVVCKGPTV 380
            +L  ++DK++ +K  GGR V GIL+G DP +N+V+D   E       AT   +N  ++G+VV +G ++
Sbjct:    8 ELKKFMDKKLSLKLNGGRHVQGILRGFDPFMNLVIDECVEM------ATSGQQN--NIGMVVIRGNSI 67          
BLAST of Sm domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9CQQ8|LSM7_MOUSE (U6 snRNA-associated Sm-like protein LSm7 OS=Mus musculus OX=10090 GN=Lsm7 PE=1 SV=1)

HSP 1 Score: 139.813 bits (351), Expect = 1.814e-42
Identity = 67/94 (71.28%), Postives = 78/94 (82.98%), Query Frame = 3
Query:  150 EKKRKETIIDLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTRDLGLVVCKGPTVEVIFPSDGMEPISNPFV 431
            EKK+KE+I+DLS YIDK IRVKF GGRE SGILKG DPLLN+VLD T EY+RDP+D  K+TE+TR LGLVVC+G +V +I P DGME I NPFV
Sbjct:    5 EKKKKESILDLSKYIDKTIRVKFQGGREASGILKGFDPLLNLVLDGTMEYMRDPDDQYKLTEDTRQLGLVVCRGTSVVLICPQDGMEAIPNPFV 98          
BLAST of Sm domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9UK45|LSM7_HUMAN (U6 snRNA-associated Sm-like protein LSm7 OS=Homo sapiens OX=9606 GN=LSM7 PE=1 SV=1)

HSP 1 Score: 139.043 bits (349), Expect = 3.346e-42
Identity = 66/94 (70.21%), Postives = 78/94 (82.98%), Query Frame = 3
Query:  150 EKKRKETIIDLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTRDLGLVVCKGPTVEVIFPSDGMEPISNPFV 431
            EKK+KE+I+DLS YIDK IRVKF GGRE SGILKG DPLLN+VLD T EY+RDP+D  K+TE+TR LGLVVC+G +V +I P DGME I NPF+
Sbjct:    5 EKKKKESILDLSKYIDKTIRVKFQGGREASGILKGFDPLLNLVLDGTIEYMRDPDDQYKLTEDTRQLGLVVCRGTSVVLICPQDGMEAIPNPFI 98          
BLAST of Sm domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9SI54|LSM7_ARATH (Sm-like protein LSM7 OS=Arabidopsis thaliana OX=3702 GN=LSM7 PE=1 SV=1)

HSP 1 Score: 110.153 bits (274), Expect = 6.714e-31
Identity = 49/91 (53.85%), Postives = 69/91 (75.82%), Query Frame = 3
Query:  159 RKETIIDLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTRDLGLVVCKGPTVEVIFPSDGMEPISNPFV 431
            RKET++DL+ ++DK ++VK  GGR+V+G LKG D LLN+VLD   E++RD +D  K T+ TR LGL+VC+G  V ++ P+DG E I+NPFV
Sbjct:    4 RKETVLDLAKFVDKGVQVKLTGGRQVTGTLKGYDQLLNLVLDEAVEFVRDHDDPLKTTDQTRRLGLIVCRGTAVMLVSPTDGTEEIANPFV 94          
BLAST of Sm domain-containing protein vs. UniProt/SwissProt
Match: sp|O74499|LSM7_SCHPO (U6 snRNA-associated Sm-like protein LSm7 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=lsm7 PE=1 SV=1)

HSP 1 Score: 105.145 bits (261), Expect = 1.183e-28
Identity = 53/96 (55.21%), Postives = 68/96 (70.83%), Query Frame = 3
Query:  150 EKKRKETIIDLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTRDLGLVVCKGPTVEVIFPSDGMEPISNPFVDT 437
            E+ RKE+I+DLS Y D+RI+  F GGR+++GILKG D L+N+VLD   E LR+PED  K+T   R LGLVV +G T+ +I P DG E I NPFV  
Sbjct:   18 ERPRKESILDLSRYQDQRIQATFTGGRQITGILKGFDQLMNLVLDDVEEQLRNPEDG-KLTGAIRKLGLVVVRGTTLVLIAPMDGSEEIPNPFVQA 112          
BLAST of Sm domain-containing protein vs. UniProt/SwissProt
Match: sp|Q54HF6|LSM7_DICDI (Probable U6 snRNA-associated Sm-like protein LSm7 OS=Dictyostelium discoideum OX=44689 GN=lsm7 PE=3 SV=1)

HSP 1 Score: 100.908 bits (250), Expect = 3.485e-27
Identity = 48/90 (53.33%), Postives = 65/90 (72.22%), Query Frame = 3
Query:  159 RKETIIDLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTRDLGLVVCKGPTVEVIFPSDGMEPISNPF 428
            +KE+I+DL  ++ K I VKF GGREV GILKG D L+N+ LD T E++RD ED    T+  R LGLVVC+G +V ++ P++G EPI NP+
Sbjct:    8 KKESILDLQKFLGKEICVKFTGGREVQGILKGYDQLVNITLDQTQEFIRDAEDPLITTDEKRFLGLVVCRGSSVMMVCPTEGCEPIDNPY 97          
BLAST of Sm domain-containing protein vs. TrEMBL
Match: A0A183APX9 (Sm domain-containing protein OS=Echinostoma caproni OX=27848 GN=ECPE_LOCUS9015 PE=4 SV=1)

HSP 1 Score: 152.525 bits (384), Expect = 4.676e-45
Identity = 69/94 (73.40%), Postives = 85/94 (90.43%), Query Frame = 3
Query:  150 EKKRKETIIDLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTRDLGLVVCKGPTVEVIFPSDGMEPISNPFV 431
            EK+RKE+IIDLS Y+DKRIRVKF+GGRE +GILKGCD L NMVLD TTEYLRDP+D  ++TE+TR+LGLVVC+GP+VE++ P+DGME I+NPFV
Sbjct:    9 EKRRKESIIDLSKYLDKRIRVKFSGGREATGILKGCDNLQNMVLDCTTEYLRDPDDPHRLTEDTRELGLVVCRGPSVELVCPADGMEAIANPFV 102          
BLAST of Sm domain-containing protein vs. TrEMBL
Match: A0A0X3P1A4 (U6 snRNA-associated Sm-like protein LSm7 OS=Schistocephalus solidus OX=70667 GN=LSM7 PE=4 SV=1)

HSP 1 Score: 150.599 bits (379), Expect = 2.634e-44
Identity = 68/96 (70.83%), Postives = 85/96 (88.54%), Query Frame = 3
Query:  150 EKKRKETIIDLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTRDLGLVVCKGPTVEVIFPSDGMEPISNPFVDT 437
            EKKRKE+IIDLS Y+DKRIRVKF GGRE +GILKGCD L NMVLD TTEYLR+P+D ++++E+TR+LGLVVC+GP+VE++ P+DGME I+NPF  T
Sbjct:    9 EKKRKESIIDLSKYLDKRIRVKFTGGREATGILKGCDNLQNMVLDNTTEYLREPDDPSRLSEDTRELGLVVCRGPSVELVCPADGMEAIANPFAQT 104          
BLAST of Sm domain-containing protein vs. TrEMBL
Match: A0A3P7PVA9 (Sm domain-containing protein OS=Dibothriocephalus latus OX=60516 GN=DILT_LOCUS14315 PE=4 SV=1)

HSP 1 Score: 149.828 bits (377), Expect = 7.285e-44
Identity = 67/94 (71.28%), Postives = 84/94 (89.36%), Query Frame = 3
Query:  150 EKKRKETIIDLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTRDLGLVVCKGPTVEVIFPSDGMEPISNPFV 431
            EKKRKE+IIDLS Y+DKRIRVKF GGRE +GILKGCD L NMVLD TTEYLR+P+D ++++E+TR+LGLVVC+GP+VE++ P+DGME I+NPF 
Sbjct:    9 EKKRKESIIDLSKYLDKRIRVKFTGGREATGILKGCDNLQNMVLDNTTEYLREPDDPSRLSEDTRELGLVVCRGPSVELVCPADGMEAIANPFA 102          
BLAST of Sm domain-containing protein vs. TrEMBL
Match: A0A0R3UPV9 (Sm domain-containing protein OS=Mesocestoides corti OX=53468 GN=MCOS_LOCUS9897 PE=4 SV=1)

HSP 1 Score: 146.747 bits (369), Expect = 1.249e-42
Identity = 67/104 (64.42%), Postives = 89/104 (85.58%), Query Frame = 3
Query:  120 MAANKDKLSFEKKRKETIIDLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTRDLGLVVCKGPTVEVIFPSDGMEPISNPFV 431
            M+ ++ + + ++ +KE+IIDL+ Y+DKRIRVKF GGRE +GILKGCD L NMVLD T EYLRDPED T++TE++R+LGLVVC+GP+VE++ P+DGME ISNPFV
Sbjct:    1 MSGDQQQTT-KRPKKESIIDLTRYLDKRIRVKFTGGREATGILKGCDNLQNMVLDNTIEYLRDPEDHTRLTEDSRELGLVVCRGPSVELVCPADGMEAISNPFV 103          
BLAST of Sm domain-containing protein vs. TrEMBL
Match: A0A4S2M725 (Sm domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_002214 PE=4 SV=1)

HSP 1 Score: 145.591 bits (366), Expect = 2.782e-42
Identity = 65/94 (69.15%), Postives = 84/94 (89.36%), Query Frame = 3
Query:  150 EKKRKETIIDLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTRDLGLVVCKGPTVEVIFPSDGMEPISNPFV 431
            EK+RKE+IIDL+ Y+DK+IRVKF+GGRE +GILKGCD L NMVLD TTE+LRDP+D  +++E+TR+LGLVVC+GP+VE++ P+DGME I NPFV
Sbjct:    9 EKRRKESIIDLNKYLDKKIRVKFSGGREATGILKGCDNLQNMVLDCTTEFLRDPDDPHRLSEDTRELGLVVCRGPSVELVCPADGMEAIPNPFV 102          
BLAST of Sm domain-containing protein vs. Ensembl Cavefish
Match: lsm7 (LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated [Source:NCBI gene;Acc:103032086])

HSP 1 Score: 135.961 bits (341), Expect = 5.711e-42
Identity = 65/94 (69.15%), Postives = 76/94 (80.85%), Query Frame = 3
Query:  150 EKKRKETIIDLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTRDLGLVVCKGPTVEVIFPSDGMEPISNPFV 431
            EKK+KE+I DLS YIDK IRVKF GGRE SG+LKG DPLLN+VLD T EY+RDP+D  K+TE+TR LGLVVC+G  V +I P DGME I NPF+
Sbjct:    5 EKKKKESIFDLSKYIDKPIRVKFQGGREASGVLKGFDPLLNLVLDGTIEYMRDPDDQYKLTEDTRQLGLVVCRGTAVVLICPQDGMEAIPNPFI 98          
BLAST of Sm domain-containing protein vs. Ensembl Cavefish
Match: snrpg (small nuclear ribonucleoprotein polypeptide G [Source:NCBI gene;Acc:107196920])

HSP 1 Score: 44.669 bits (104), Expect = 1.061e-6
Identity = 24/68 (35.29%), Postives = 41/68 (60.29%), Query Frame = 3
Query:  177 DLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTRDLGLVVCKGPTV 380
            +L  ++DK++ +K  GGR V GIL+G DP +N+V+D   E       +    +NT  +G+VV +G ++
Sbjct:    8 ELKKFMDKKLSLKLNGGRHVQGILRGFDPFMNLVVDDCLEM------SPGGQQNT--IGMVVIRGNSI 67          
BLAST of Sm domain-containing protein vs. Ensembl Cavefish
Match: snrpg (small nuclear ribonucleoprotein polypeptide G [Source:NCBI gene;Acc:107196920])

HSP 1 Score: 43.5134 bits (101), Expect = 4.035e-6
Identity = 18/40 (45.00%), Postives = 28/40 (70.00%), Query Frame = 3
Query:  177 DLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTE 296
            +L  ++DK++ +K  GGR V GIL+G DP +N+V+D   E
Sbjct:    8 ELKKFMDKKLSLKLNGGRHVQGILRGFDPFMNLVVDDCLE 47          
BLAST of Sm domain-containing protein vs. Ensembl Sea Lamprey
Match: snrpg (small nuclear ribonucleoprotein polypeptide G [Source:ZFIN;Acc:ZDB-GENE-040912-105])

HSP 1 Score: 42.3578 bits (98), Expect = 1.710e-6
Identity = 23/68 (33.82%), Postives = 41/68 (60.29%), Query Frame = 3
Query:  177 DLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTRDLGLVVCKGPTV 380
            +L  ++DK++ +K  G R V+GIL+G DP +N+V+D   E  +         +N  D+G+VV +G ++
Sbjct:    8 ELKKFMDKKLSLKLNGSRTVTGILRGFDPFMNLVMDECFELCQGG------VQN--DVGMVVIRGNSI 67          
BLAST of Sm domain-containing protein vs. Ensembl Yeast
Match: LSM7 (Lsm (Like Sm) protein; part of heteroheptameric complexes (Lsm2p-7p and either Lsm1p or 8p): cytoplasmic Lsm1p complex involved in mRNA decay; nuclear Lsm8p complex part of U6 snRNP and possibly involved in processing tRNA, snoRNA, and rRNA; protein abundance increases and forms cytoplasmic foci in response to DNA replication stress [Source:SGD;Acc:S000005091])

HSP 1 Score: 79.7221 bits (195), Expect = 1.442e-20
Identity = 39/89 (43.82%), Postives = 58/89 (65.17%), Query Frame = 3
Query:  147 FEKKRKETIIDLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATK---ITENTRDLGLVVCKGPTVEVIFPSDG 404
            FE  ++E I+DL+ Y D +IRVK  GG+ V G+LKG D L+N+VLD T EY+ +P+D      I++N R LGL V +G  +  +  ++G
Sbjct:   19 FEGPKREAILDLAKYKDSKIRVKLMGGKLVIGVLKGYDQLMNLVLDDTVEYMSNPDDENNTELISKNARKLGLTVIRGTILVSLSSAEG 107          
BLAST of Sm domain-containing protein vs. Ensembl Yeast
Match: SMX2 (Core Sm protein Sm G; part of heteroheptameric complex (with Smb1p, Smd1p, Smd2p, Smd3p, Sme1p, and Smx3p) that is part of the spliceosomal U1, U2, U4, and U5 snRNPs; homolog of human Sm G [Source:SGD;Acc:S000002965])

HSP 1 Score: 40.0466 bits (92), Expect = 7.501e-6
Identity = 26/65 (40.00%), Postives = 37/65 (56.92%), Query Frame = 3
Query:  189 YIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTRDLGL-VVCKGPTV 380
            Y+DK+I +   G R+V+GIL+G D  LN+VLD   E   + ED      N   LGL  V +G ++
Sbjct:   10 YMDKKILLNINGSRKVAGILRGYDIFLNVVLDDAMEI--NGEDPA----NNHQLGLQTVIRGNSI 68          
BLAST of Sm domain-containing protein vs. Ensembl Nematostella
Match: EDO41002 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S5M5])

HSP 1 Score: 125.176 bits (313), Expect = 3.805e-38
Identity = 58/96 (60.42%), Postives = 75/96 (78.12%), Query Frame = 3
Query:  144 SFEKKRKETIIDLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTRDLGLVVCKGPTVEVIFPSDGMEPISNPFV 431
            S E+K K++I DLS ++DK +RVKF GGRE SG+LKG D LLN+VLD T EYLRDP+D  K+++ TR LGLVVC+G  V ++ P DGME I+NPF+
Sbjct:    3 SGERKEKKSIFDLSKFLDKGVRVKFQGGREASGVLKGFDALLNLVLDNTIEYLRDPDDPLKLSDETRQLGLVVCRGTAVVLVCPMDGMEAIANPFI 98          
BLAST of Sm domain-containing protein vs. Ensembl Nematostella
Match: EDO48813 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RII4])

HSP 1 Score: 50.8322 bits (120), Expect = 2.355e-9
Identity = 25/68 (36.76%), Postives = 40/68 (58.82%), Query Frame = 3
Query:  177 DLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTRDLGLVVCKGPTV 380
            +L  Y+DK++ +K  GGR VSG+L+G DP +N+VLD   E +   E           +G+VV +G ++
Sbjct:    8 ELKKYMDKKLSLKLNGGRHVSGVLRGYDPFMNLVLDDAVENVSGNEKHA--------IGMVVIRGNSI 67          
BLAST of Sm domain-containing protein vs. Ensembl Medaka
Match: lsm7 (LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated [Source:NCBI gene;Acc:101175386])

HSP 1 Score: 136.732 bits (343), Expect = 3.586e-42
Identity = 65/94 (69.15%), Postives = 77/94 (81.91%), Query Frame = 3
Query:  150 EKKRKETIIDLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTRDLGLVVCKGPTVEVIFPSDGMEPISNPFV 431
            EKK+KE+I DLS YIDK IRVKF GGRE SG+LKG DPLLN+VLD T EY+RDP+D  K+TE+TR LGLVVC+G +V +I P DGME I NPF+
Sbjct:    5 EKKKKESIFDLSKYIDKPIRVKFQGGREASGVLKGFDPLLNLVLDGTIEYMRDPDDQLKLTEDTRQLGLVVCRGTSVVLICPQDGMEAIPNPFI 98          
BLAST of Sm domain-containing protein vs. Ensembl Medaka
Match: lsm7 (LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated [Source:NCBI gene;Acc:101175386])

HSP 1 Score: 136.732 bits (343), Expect = 6.080e-42
Identity = 65/94 (69.15%), Postives = 77/94 (81.91%), Query Frame = 3
Query:  150 EKKRKETIIDLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTRDLGLVVCKGPTVEVIFPSDGMEPISNPFV 431
            EKK+KE+I DLS YIDK IRVKF GGRE SG+LKG DPLLN+VLD T EY+RDP+D  K+TE+TR LGLVVC+G +V +I P DGME I NPF+
Sbjct:   26 EKKKKESIFDLSKYIDKPIRVKFQGGREASGVLKGFDPLLNLVLDGTIEYMRDPDDQLKLTEDTRQLGLVVCRGTSVVLICPQDGMEAIPNPFI 119          
BLAST of Sm domain-containing protein vs. Ensembl Medaka
Match: snrpg (small nuclear ribonucleoprotein polypeptide G [Source:NCBI gene;Acc:101154947])

HSP 1 Score: 45.4394 bits (106), Expect = 7.017e-7
Identity = 24/68 (35.29%), Postives = 40/68 (58.82%), Query Frame = 3
Query:  177 DLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTRDLGLVVCKGPTV 380
            +L  ++DK++ +K  GGR V GIL+G DP +N+V+D   E            +NT  +G+VV +G ++
Sbjct:    8 ELKKFMDKKLSLKLNGGRHVQGILRGFDPFMNLVMDDCLEM------GPGGQQNT--IGMVVIRGNSI 67          
BLAST of Sm domain-containing protein vs. Ensembl Medaka
Match: snrpg (small nuclear ribonucleoprotein polypeptide G [Source:NCBI gene;Acc:101154947])

HSP 1 Score: 45.0542 bits (105), Expect = 1.611e-6
Identity = 17/36 (47.22%), Postives = 27/36 (75.00%), Query Frame = 3
Query:  177 DLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLD 284
            +L  ++DK++ +K  GGR V GIL+G DP +N+V+D
Sbjct:    8 ELKKFMDKKLSLKLNGGRHVQGILRGFDPFMNLVMD 43          
BLAST of Sm domain-containing protein vs. Planmine SMEST
Match: SMESG000081731.1 (SMESG000081731.1)

HSP 1 Score: 46.9802 bits (110), Expect = 1.125e-7
Identity = 23/75 (30.67%), Postives = 43/75 (57.33%), Query Frame = 3
Query:  177 DLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTRDLGLVVCKGPTVEVIFPSD 401
            +L  Y+DKR+ +K  G R V GI++G DP +N+VL+   E  +D ++         ++G +V +G ++ ++   D
Sbjct:    8 ELKKYMDKRMTLKLNGHRRVKGIMRGFDPFMNIVLENAVEIDKDNQEV--------NIGTIVIRGNSISILEAVD 74          
BLAST of Sm domain-containing protein vs. Planmine SMEST
Match: SMESG000081727.1 (SMESG000081727.1)

HSP 1 Score: 46.9802 bits (110), Expect = 1.125e-7
Identity = 23/75 (30.67%), Postives = 43/75 (57.33%), Query Frame = 3
Query:  177 DLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTRDLGLVVCKGPTVEVIFPSD 401
            +L  Y+DKR+ +K  G R V GI++G DP +N+VL+   E  +D ++         ++G +V +G ++ ++   D
Sbjct:    8 ELKKYMDKRMTLKLNGHRRVKGIMRGFDPFMNIVLENAVEIDKDNQEV--------NIGTIVIRGNSISILEAVD 74          
The following BLAST results are available for this feature:
BLAST of Sm domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
LSM76.967e-4370.21LSM7 homolog, U6 small nuclear RNA and mRNA degrad... [more]
LSM76.770e-1461.36LSM7 homolog, U6 small nuclear RNA and mRNA degrad... [more]
LSM72.173e-872.73LSM7 homolog, U6 small nuclear RNA and mRNA degrad... [more]
LSM73.599e-879.31LSM7 homolog, U6 small nuclear RNA and mRNA degrad... [more]
SNRPG6.083e-835.82small nuclear ribonucleoprotein polypeptide G [Sou... [more]
back to top
BLAST of Sm domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2
Match NameE-valueIdentityDescription
lsm-72.653e-3453.76LSM Sm-like protein [Source:UniProtKB/TrEMBL;Acc:... [more]
snr-78.774e-1137.33Probable small nuclear ribonucleoprotein G [Sourc... [more]
back to top
BLAST of Sm domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
LSm74.450e-3864.21gene:FBgn0261068 transcript:FBtr0343770[more]
LSm74.450e-3864.21gene:FBgn0261068 transcript:FBtr0080934[more]
LSm74.450e-3864.21gene:FBgn0261068 transcript:FBtr0308804[more]
SNRPG5.516e-1041.18gene:FBgn0261791 transcript:FBtr0112993[more]
SNRPG5.516e-1041.18gene:FBgn0261791 transcript:FBtr0074377[more]
back to top
BLAST of Sm domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 3
Match NameE-valueIdentityDescription
lsm73.614e-4268.09LSM7 homolog, U6 small nuclear RNA and mRNA degrad... [more]
lsm74.082e-1461.36LSM7 homolog, U6 small nuclear RNA and mRNA degrad... [more]
snrpg1.495e-738.24small nuclear ribonucleoprotein polypeptide G [Sou... [more]
back to top
BLAST of Sm domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 4
Match NameE-valueIdentityDescription
lsm76.315e-4370.21LSM7 homolog, U6 small nuclear RNA and mRNA degrad... [more]
lsm76.817e-4370.21LSM7 homolog, U6 small nuclear RNA and mRNA degrad... [more]
lsm72.923e-1463.64LSM7 homolog, U6 small nuclear RNA and mRNA degrad... [more]
snrpg2.198e-736.76small nuclear ribonucleoprotein polypeptide G [Sou... [more]
back to top
BLAST of Sm domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 3
Match NameE-valueIdentityDescription
Lsm72.593e-4371.28LSM7 homolog, U6 small nuclear RNA and mRNA degrad... [more]
Lsm72.241e-2176.92LSM7 homolog, U6 small nuclear RNA and mRNA degrad... [more]
Snrpg4.868e-836.76small nuclear ribonucleoprotein polypeptide G [Sou... [more]
back to top
BLAST of Sm domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q9CQQ8|LSM7_MOUSE1.814e-4271.28U6 snRNA-associated Sm-like protein LSm7 OS=Mus mu... [more]
sp|Q9UK45|LSM7_HUMAN3.346e-4270.21U6 snRNA-associated Sm-like protein LSm7 OS=Homo s... [more]
sp|Q9SI54|LSM7_ARATH6.714e-3153.85Sm-like protein LSM7 OS=Arabidopsis thaliana OX=37... [more]
sp|O74499|LSM7_SCHPO1.183e-2855.21U6 snRNA-associated Sm-like protein LSm7 OS=Schizo... [more]
sp|Q54HF6|LSM7_DICDI3.485e-2753.33Probable U6 snRNA-associated Sm-like protein LSm7 ... [more]
back to top
BLAST of Sm domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A183APX94.676e-4573.40Sm domain-containing protein OS=Echinostoma capron... [more]
A0A0X3P1A42.634e-4470.83U6 snRNA-associated Sm-like protein LSm7 OS=Schist... [more]
A0A3P7PVA97.285e-4471.28Sm domain-containing protein OS=Dibothriocephalus ... [more]
A0A0R3UPV91.249e-4264.42Sm domain-containing protein OS=Mesocestoides cort... [more]
A0A4S2M7252.782e-4269.15Sm domain-containing protein OS=Opisthorchis felin... [more]
back to top
BLAST of Sm domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 3
Match NameE-valueIdentityDescription
lsm75.711e-4269.15LSM7 homolog, U6 small nuclear RNA and mRNA degrad... [more]
snrpg1.061e-635.29small nuclear ribonucleoprotein polypeptide G [Sou... [more]
snrpg4.035e-645.00small nuclear ribonucleoprotein polypeptide G [Sou... [more]
back to top
BLAST of Sm domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
snrpg1.710e-633.82small nuclear ribonucleoprotein polypeptide G [Sou... [more]
back to top
BLAST of Sm domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 2
Match NameE-valueIdentityDescription
LSM71.442e-2043.82Lsm (Like Sm) protein; part of heteroheptameric co... [more]
SMX27.501e-640.00Core Sm protein Sm G; part of heteroheptameric com... [more]
back to top
BLAST of Sm domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO410023.805e-3860.42Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO488132.355e-936.76Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
back to top
BLAST of Sm domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 4
Match NameE-valueIdentityDescription
lsm73.586e-4269.15LSM7 homolog, U6 small nuclear RNA and mRNA degrad... [more]
lsm76.080e-4269.15LSM7 homolog, U6 small nuclear RNA and mRNA degrad... [more]
snrpg7.017e-735.29small nuclear ribonucleoprotein polypeptide G [Sou... [more]
snrpg1.611e-647.22small nuclear ribonucleoprotein polypeptide G [Sou... [more]
back to top
BLAST of Sm domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 2
Match NameE-valueIdentityDescription
SMESG000081731.11.125e-730.67SMESG000081731.1[more]
SMESG000081727.11.125e-730.67SMESG000081727.1[more]
back to top
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30019973 ID=SMED30019973|Name=Sm domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=473bp
CATTTAACATCAATTTTAATTGCAATACTAAAAAGCATTAATTGAAAATA
CTTTACAAAAAAATACAGTCAAAAAATAATTCACAGAAATTTATTTTTCG
AAGTGAAACATTTAAAATTATGGCTGCAAATAAGGATAAATTGTCTTTTG
AAAAAAAACGAAAGGAAACTATAATAGATTTATCGATATATATCGATAAA
CGAATAAGAGTAAAATTTGCTGGTGGTCGGGAAGTTAGTGGAATTCTCAA
AGGTTGTGATCCATTATTAAATATGGTTTTGGACGTTACAACAGAATACT
TGAGAGACCCAGAAGATGCAACAAAAATTACAGAAAATACAAGAGATTTA
GGTCTTGTTGTGTGCAAGGGTCCAACAGTTGAAGTTATTTTTCCATCTGA
TGGTATGGAACCAATAAGTAATCCTTTCGTAGATACTGGTTGTTAAATAT
AAATTTTTGTACTGAAAAAAAAA
back to top

protein sequence of SMED30019973-orf-1

>SMED30019973-orf-1 ID=SMED30019973-orf-1|Name=SMED30019973-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=109bp
MAANKDKLSFEKKRKETIIDLSIYIDKRIRVKFAGGREVSGILKGCDPLL
NMVLDVTTEYLRDPEDATKITENTRDLGLVVCKGPTVEVIFPSDGMEPIS
NPFVDTGC*
back to top
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
PLANA:0000101muscle cell
PLANA:0000142posterior region of the whole animal
PLANA:0000418head
PLANA:0002056medial muscle cell
PLANA:0002109X1 cell
PLANA:0003001lateral region of the whole animal
PLANA:0003117parapharyngeal cell
Vocabulary: INTERPRO
TermDefinition
IPR017132Lsm7
IPR001163LSM_dom_euk/arc
IPR010920LSM_dom_sf
Vocabulary: biological process
TermDefinition
GO:0000398mRNA splicing, via spliceosome
GO:0000956nuclear-transcribed mRNA catabolic process
Vocabulary: cellular component
TermDefinition
GO:0030529intracellular ribonucleoprotein complex
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001163LSM domain, eukaryotic/archaea-typeSMARTSM00651Sm3coord: 19..92
e-value: 3.2E-15
score: 66.6
IPR001163LSM domain, eukaryotic/archaea-typePFAMPF01423LSMcoord: 21..90
e-value: 1.0E-16
score: 60.3
NoneNo IPR availableGENE3DG3DSA:2.30.30.100coord: 1..101
e-value: 1.7E-27
score: 97.4
NoneNo IPR availablePIRSFPIRSF037188Lsm7coord: 1..107
e-value: 1.3E-40
score: 135.5
NoneNo IPR availablePANTHERPTHR10553SMALL NUCLEAR RIBONUCLEOPROTEINcoord: 9..105
NoneNo IPR availablePANTHERPTHR10553:SF5U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM7coord: 9..105
IPR017132Sm-like protein Lsm7CDDcd01729LSm7coord: 15..103
e-value: 9.07184E-53
score: 158.133
IPR010920LSM domain superfamilySUPERFAMILYSSF50182Sm-like ribonucleoproteinscoord: 22..96