Sm domain-containing protein
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30019973 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 3
Homology
BLAST of Sm domain-containing protein vs. Ensembl Human
Match: LSM7 (LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated [Source:HGNC Symbol;Acc:HGNC:20470]) HSP 1 Score: 139.043 bits (349), Expect = 6.967e-43 Identity = 66/94 (70.21%), Postives = 78/94 (82.98%), Query Frame = 3 Query: 150 EKKRKETIIDLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTRDLGLVVCKGPTVEVIFPSDGMEPISNPFV 431 EKK+KE+I+DLS YIDK IRVKF GGRE SGILKG DPLLN+VLD T EY+RDP+D K+TE+TR LGLVVC+G +V +I P DGME I NPF+ Sbjct: 5 EKKKKESILDLSKYIDKTIRVKFQGGREASGILKGFDPLLNLVLDGTIEYMRDPDDQYKLTEDTRQLGLVVCRGTSVVLICPQDGMEAIPNPFI 98
BLAST of Sm domain-containing protein vs. Ensembl Human
Match: LSM7 (LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated [Source:HGNC Symbol;Acc:HGNC:20470]) HSP 1 Score: 63.5438 bits (153), Expect = 6.770e-14 Identity = 27/44 (61.36%), Postives = 35/44 (79.55%), Query Frame = 3 Query: 300 LRDPEDATKITENTRDLGLVVCKGPTVEVIFPSDGMEPISNPFV 431 +RDP+D K+TE+TR LGLVVC+G +V +I P DGME I NPF+ Sbjct: 1 MRDPDDQYKLTEDTRQLGLVVCRGTSVVLICPQDGMEAIPNPFI 44
BLAST of Sm domain-containing protein vs. Ensembl Human
Match: LSM7 (LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated [Source:HGNC Symbol;Acc:HGNC:20470]) HSP 1 Score: 49.6766 bits (117), Expect = 2.173e-8 Identity = 24/33 (72.73%), Postives = 27/33 (81.82%), Query Frame = 3 Query: 150 EKKRKETIIDLSIYIDKRIRVKFAGGREVSGIL 248 EKK+KE+I+DLS YIDK IRVKF GGRE S L Sbjct: 3 EKKKKESILDLSKYIDKTIRVKFQGGREESQAL 35
BLAST of Sm domain-containing protein vs. Ensembl Human
Match: LSM7 (LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated [Source:HGNC Symbol;Acc:HGNC:20470]) HSP 1 Score: 48.521 bits (114), Expect = 3.599e-8 Identity = 23/29 (79.31%), Postives = 26/29 (89.66%), Query Frame = 3 Query: 150 EKKRKETIIDLSIYIDKRIRVKFAGGREV 236 EKK+KE+I+DLS YIDK IRVKF GGREV Sbjct: 5 EKKKKESILDLSKYIDKTIRVKFQGGREV 33
BLAST of Sm domain-containing protein vs. Ensembl Human
Match: SNRPG (small nuclear ribonucleoprotein polypeptide G [Source:HGNC Symbol;Acc:HGNC:11163]) HSP 1 Score: 48.521 bits (114), Expect = 6.083e-8 Identity = 24/67 (35.82%), Postives = 42/67 (62.69%), Query Frame = 3 Query: 180 LSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTRDLGLVVCKGPTV 380 + +++DK++ +K GGR V GIL+G DP +N+V+D E AT +N ++G+VV +G ++ Sbjct: 1 MCLFMDKKLSLKLNGGRHVQGILRGFDPFMNLVIDECVEM------ATSGQQN--NIGMVVIRGNSI 59
BLAST of Sm domain-containing protein vs. Ensembl Celegans
Match: lsm-7 (LSM Sm-like protein [Source:UniProtKB/TrEMBL;Acc:Q23543]) HSP 1 Score: 116.316 bits (290), Expect = 2.653e-34 Identity = 50/93 (53.76%), Postives = 72/93 (77.42%), Query Frame = 3 Query: 153 KKRKETIIDLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTRDLGLVVCKGPTVEVIFPSDGMEPISNPFV 431 K++KE+++DL+ ++DK IRVKF GGRE SG+L+G D LLNMVLD EYLRDP++ + + + TR LGL+V +G + V+ P+DG+E I+NPF Sbjct: 7 KRKKESVVDLTRFLDKEIRVKFQGGREASGVLRGFDQLLNMVLDDCREYLRDPQNPSVVGDETRQLGLIVARGTAITVVSPADGLEQIANPFA 99
BLAST of Sm domain-containing protein vs. Ensembl Celegans
Match: snr-7 (Probable small nuclear ribonucleoprotein G [Source:UniProtKB/Swiss-Prot;Acc:Q9N4G9]) HSP 1 Score: 55.0694 bits (131), Expect = 8.774e-11 Identity = 28/75 (37.33%), Postives = 44/75 (58.67%), Query Frame = 3 Query: 177 DLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTRDLGLVVCKGPTVEVIFPSD 401 +L Y+DK + +K G R VSGIL+G DP +NMV+D EY +D + +LG+ V +G +V ++ P + Sbjct: 8 ELKKYMDKEMDLKLNGNRRVSGILRGFDPFMNMVIDEAVEYQKD--------GGSVNLGMTVIRGNSVVIMEPKE 74
BLAST of Sm domain-containing protein vs. Ensembl Fly
Match: LSm7 (gene:FBgn0261068 transcript:FBtr0343770) HSP 1 Score: 126.331 bits (316), Expect = 4.450e-38 Identity = 61/95 (64.21%), Postives = 77/95 (81.05%), Query Frame = 3 Query: 150 EKKRKETIIDLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKIT-ENTRDLGLVVCKGPTVEVIFPSDGMEPISNPFV 431 EK+RKE+I+DLS Y++K+IRVKFAGGRE SGILKG D LLN+VLD T EYLRD ++ K+T E TR LGLVVC+G + +I P DG+E I+NPF+ Sbjct: 14 EKRRKESILDLSKYLEKQIRVKFAGGREASGILKGYDALLNLVLDNTVEYLRDSDEPYKLTEEQTRSLGLVVCRGTALVLICPQDGVESIANPFI 108
BLAST of Sm domain-containing protein vs. Ensembl Fly
Match: LSm7 (gene:FBgn0261068 transcript:FBtr0080934) HSP 1 Score: 126.331 bits (316), Expect = 4.450e-38 Identity = 61/95 (64.21%), Postives = 77/95 (81.05%), Query Frame = 3 Query: 150 EKKRKETIIDLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKIT-ENTRDLGLVVCKGPTVEVIFPSDGMEPISNPFV 431 EK+RKE+I+DLS Y++K+IRVKFAGGRE SGILKG D LLN+VLD T EYLRD ++ K+T E TR LGLVVC+G + +I P DG+E I+NPF+ Sbjct: 14 EKRRKESILDLSKYLEKQIRVKFAGGREASGILKGYDALLNLVLDNTVEYLRDSDEPYKLTEEQTRSLGLVVCRGTALVLICPQDGVESIANPFI 108
BLAST of Sm domain-containing protein vs. Ensembl Fly
Match: LSm7 (gene:FBgn0261068 transcript:FBtr0308804) HSP 1 Score: 126.331 bits (316), Expect = 4.450e-38 Identity = 61/95 (64.21%), Postives = 77/95 (81.05%), Query Frame = 3 Query: 150 EKKRKETIIDLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKIT-ENTRDLGLVVCKGPTVEVIFPSDGMEPISNPFV 431 EK+RKE+I+DLS Y++K+IRVKFAGGRE SGILKG D LLN+VLD T EYLRD ++ K+T E TR LGLVVC+G + +I P DG+E I+NPF+ Sbjct: 14 EKRRKESILDLSKYLEKQIRVKFAGGREASGILKGYDALLNLVLDNTVEYLRDSDEPYKLTEEQTRSLGLVVCRGTALVLICPQDGVESIANPFI 108
BLAST of Sm domain-containing protein vs. Ensembl Fly
Match: SNRPG (gene:FBgn0261791 transcript:FBtr0112993) HSP 1 Score: 53.5286 bits (127), Expect = 5.516e-10 Identity = 28/68 (41.18%), Postives = 45/68 (66.18%), Query Frame = 3 Query: 189 YIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTR-DLGLVVCKGPTVEVI 389 Y+DKR+ +K GGR V+GIL+G DP +N+VLD T E +D NT+ ++G+VV +G ++ ++ Sbjct: 12 YMDKRMMLKLNGGRAVTGILRGFDPFMNVVLDDTVEECKD---------NTKNNIGMVVIRGNSIVMV 70
BLAST of Sm domain-containing protein vs. Ensembl Fly
Match: SNRPG (gene:FBgn0261791 transcript:FBtr0074377) HSP 1 Score: 53.5286 bits (127), Expect = 5.516e-10 Identity = 28/68 (41.18%), Postives = 45/68 (66.18%), Query Frame = 3 Query: 189 YIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTR-DLGLVVCKGPTVEVI 389 Y+DKR+ +K GGR V+GIL+G DP +N+VLD T E +D NT+ ++G+VV +G ++ ++ Sbjct: 12 YMDKRMMLKLNGGRAVTGILRGFDPFMNVVLDDTVEECKD---------NTKNNIGMVVIRGNSIVMV 70
BLAST of Sm domain-containing protein vs. Ensembl Zebrafish
Match: lsm7 (LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated [Source:ZFIN;Acc:ZDB-GENE-030131-8284]) HSP 1 Score: 136.732 bits (343), Expect = 3.614e-42 Identity = 64/94 (68.09%), Postives = 77/94 (81.91%), Query Frame = 3 Query: 150 EKKRKETIIDLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTRDLGLVVCKGPTVEVIFPSDGMEPISNPFV 431 +KK+KE+I DLS YIDK IRVKF GGRE SG+LKG DPLLN+VLD T EY+RDP+D K+TE+TR LGLVVC+G +V +I P DGME I NPF+ Sbjct: 5 DKKKKESIFDLSKYIDKHIRVKFQGGREASGVLKGFDPLLNLVLDGTIEYMRDPDDQYKLTEDTRQLGLVVCRGTSVVLICPQDGMEAIPNPFI 98
BLAST of Sm domain-containing protein vs. Ensembl Zebrafish
Match: lsm7 (LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated [Source:ZFIN;Acc:ZDB-GENE-030131-8284]) HSP 1 Score: 63.5438 bits (153), Expect = 4.082e-14 Identity = 27/44 (61.36%), Postives = 35/44 (79.55%), Query Frame = 3 Query: 300 LRDPEDATKITENTRDLGLVVCKGPTVEVIFPSDGMEPISNPFV 431 +RDP+D K+TE+TR LGLVVC+G +V +I P DGME I NPF+ Sbjct: 1 MRDPDDQYKLTEDTRQLGLVVCRGTSVVLICPQDGMEAIPNPFI 44
BLAST of Sm domain-containing protein vs. Ensembl Zebrafish
Match: snrpg (small nuclear ribonucleoprotein polypeptide G [Source:ZFIN;Acc:ZDB-GENE-040912-105]) HSP 1 Score: 47.3654 bits (111), Expect = 1.495e-7 Identity = 26/68 (38.24%), Postives = 41/68 (60.29%), Query Frame = 3 Query: 177 DLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTRDLGLVVCKGPTV 380 +L ++DK++ +K GGR V GIL+G DP +N+V+D T E A NT +G+VV +G ++ Sbjct: 8 ELKKFMDKKLSLKLNGGRHVQGILRGFDPFMNLVVDDTIEM------APGGQMNT--IGMVVIRGNSI 67
BLAST of Sm domain-containing protein vs. Ensembl Xenopus
Match: lsm7 (LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated [Source:NCBI gene;Acc:100127774]) HSP 1 Score: 139.043 bits (349), Expect = 6.315e-43 Identity = 66/94 (70.21%), Postives = 78/94 (82.98%), Query Frame = 3 Query: 150 EKKRKETIIDLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTRDLGLVVCKGPTVEVIFPSDGMEPISNPFV 431 EKK+KE+I+DLS YIDK IRVKF GGRE SG+LKG DPLLN+VLD T EY+RDP+D K+TE+TR LGLVVC+G +V +I P DGME I NPFV Sbjct: 5 EKKKKESILDLSKYIDKAIRVKFQGGREASGVLKGFDPLLNLVLDGTIEYMRDPDDQYKLTEDTRQLGLVVCRGTSVVLICPQDGMEAIPNPFV 98
BLAST of Sm domain-containing protein vs. Ensembl Xenopus
Match: lsm7 (LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated [Source:NCBI gene;Acc:100127774]) HSP 1 Score: 139.043 bits (349), Expect = 6.817e-43 Identity = 66/94 (70.21%), Postives = 78/94 (82.98%), Query Frame = 3 Query: 150 EKKRKETIIDLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTRDLGLVVCKGPTVEVIFPSDGMEPISNPFV 431 EKK+KE+I+DLS YIDK IRVKF GGRE SG+LKG DPLLN+VLD T EY+RDP+D K+TE+TR LGLVVC+G +V +I P DGME I NPFV Sbjct: 5 EKKKKESILDLSKYIDKAIRVKFQGGREASGVLKGFDPLLNLVLDGTIEYMRDPDDQYKLTEDTRQLGLVVCRGTSVVLICPQDGMEAIPNPFV 98
BLAST of Sm domain-containing protein vs. Ensembl Xenopus
Match: lsm7 (LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated [Source:NCBI gene;Acc:100127774]) HSP 1 Score: 64.3142 bits (155), Expect = 2.923e-14 Identity = 28/44 (63.64%), Postives = 35/44 (79.55%), Query Frame = 3 Query: 300 LRDPEDATKITENTRDLGLVVCKGPTVEVIFPSDGMEPISNPFV 431 +RDP+D K+TE+TR LGLVVC+G +V +I P DGME I NPFV Sbjct: 1 MRDPDDQYKLTEDTRQLGLVVCRGTSVVLICPQDGMEAIPNPFV 44
BLAST of Sm domain-containing protein vs. Ensembl Xenopus
Match: snrpg (small nuclear ribonucleoprotein polypeptide G [Source:NCBI gene;Acc:100125174]) HSP 1 Score: 47.3654 bits (111), Expect = 2.198e-7 Identity = 25/68 (36.76%), Postives = 42/68 (61.76%), Query Frame = 3 Query: 177 DLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTRDLGLVVCKGPTV 380 +L ++DK++ +K GGR V GIL+G DP +N+V+D TE + +NT +G+VV +G ++ Sbjct: 8 ELKKFMDKKLSLKLNGGRHVQGILRGFDPFMNLVIDECTEI------SGGGHQNT--IGMVVIRGNSI 67
BLAST of Sm domain-containing protein vs. Ensembl Mouse
Match: Lsm7 (LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated [Source:MGI Symbol;Acc:MGI:1913344]) HSP 1 Score: 139.813 bits (351), Expect = 2.593e-43 Identity = 67/94 (71.28%), Postives = 78/94 (82.98%), Query Frame = 3 Query: 150 EKKRKETIIDLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTRDLGLVVCKGPTVEVIFPSDGMEPISNPFV 431 EKK+KE+I+DLS YIDK IRVKF GGRE SGILKG DPLLN+VLD T EY+RDP+D K+TE+TR LGLVVC+G +V +I P DGME I NPFV Sbjct: 5 EKKKKESILDLSKYIDKTIRVKFQGGREASGILKGFDPLLNLVLDGTMEYMRDPDDQYKLTEDTRQLGLVVCRGTSVVLICPQDGMEAIPNPFV 98
BLAST of Sm domain-containing protein vs. Ensembl Mouse
Match: Lsm7 (LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated [Source:MGI Symbol;Acc:MGI:1913344]) HSP 1 Score: 83.1889 bits (204), Expect = 2.241e-21 Identity = 40/52 (76.92%), Postives = 45/52 (86.54%), Query Frame = 3 Query: 150 EKKRKETIIDLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLR 305 EKK+KE+I+DLS YIDK IRVKF GGRE SGILKG DPLLN+VLD T EY+R Sbjct: 5 EKKKKESILDLSKYIDKTIRVKFQGGREASGILKGFDPLLNLVLDGTMEYMR 56
BLAST of Sm domain-containing protein vs. Ensembl Mouse
Match: Snrpg (small nuclear ribonucleoprotein polypeptide G [Source:MGI Symbol;Acc:MGI:1915261]) HSP 1 Score: 48.521 bits (114), Expect = 4.868e-8 Identity = 25/68 (36.76%), Postives = 42/68 (61.76%), Query Frame = 3 Query: 177 DLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTRDLGLVVCKGPTV 380 +L ++DK++ +K GGR V GIL+G DP +N+V+D E AT +N ++G+VV +G ++ Sbjct: 8 ELKKFMDKKLSLKLNGGRHVQGILRGFDPFMNLVIDECVEM------ATSGQQN--NIGMVVIRGNSI 67
BLAST of Sm domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9CQQ8|LSM7_MOUSE (U6 snRNA-associated Sm-like protein LSm7 OS=Mus musculus OX=10090 GN=Lsm7 PE=1 SV=1) HSP 1 Score: 139.813 bits (351), Expect = 1.814e-42 Identity = 67/94 (71.28%), Postives = 78/94 (82.98%), Query Frame = 3 Query: 150 EKKRKETIIDLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTRDLGLVVCKGPTVEVIFPSDGMEPISNPFV 431 EKK+KE+I+DLS YIDK IRVKF GGRE SGILKG DPLLN+VLD T EY+RDP+D K+TE+TR LGLVVC+G +V +I P DGME I NPFV Sbjct: 5 EKKKKESILDLSKYIDKTIRVKFQGGREASGILKGFDPLLNLVLDGTMEYMRDPDDQYKLTEDTRQLGLVVCRGTSVVLICPQDGMEAIPNPFV 98
BLAST of Sm domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9UK45|LSM7_HUMAN (U6 snRNA-associated Sm-like protein LSm7 OS=Homo sapiens OX=9606 GN=LSM7 PE=1 SV=1) HSP 1 Score: 139.043 bits (349), Expect = 3.346e-42 Identity = 66/94 (70.21%), Postives = 78/94 (82.98%), Query Frame = 3 Query: 150 EKKRKETIIDLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTRDLGLVVCKGPTVEVIFPSDGMEPISNPFV 431 EKK+KE+I+DLS YIDK IRVKF GGRE SGILKG DPLLN+VLD T EY+RDP+D K+TE+TR LGLVVC+G +V +I P DGME I NPF+ Sbjct: 5 EKKKKESILDLSKYIDKTIRVKFQGGREASGILKGFDPLLNLVLDGTIEYMRDPDDQYKLTEDTRQLGLVVCRGTSVVLICPQDGMEAIPNPFI 98
BLAST of Sm domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9SI54|LSM7_ARATH (Sm-like protein LSM7 OS=Arabidopsis thaliana OX=3702 GN=LSM7 PE=1 SV=1) HSP 1 Score: 110.153 bits (274), Expect = 6.714e-31 Identity = 49/91 (53.85%), Postives = 69/91 (75.82%), Query Frame = 3 Query: 159 RKETIIDLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTRDLGLVVCKGPTVEVIFPSDGMEPISNPFV 431 RKET++DL+ ++DK ++VK GGR+V+G LKG D LLN+VLD E++RD +D K T+ TR LGL+VC+G V ++ P+DG E I+NPFV Sbjct: 4 RKETVLDLAKFVDKGVQVKLTGGRQVTGTLKGYDQLLNLVLDEAVEFVRDHDDPLKTTDQTRRLGLIVCRGTAVMLVSPTDGTEEIANPFV 94
BLAST of Sm domain-containing protein vs. UniProt/SwissProt
Match: sp|O74499|LSM7_SCHPO (U6 snRNA-associated Sm-like protein LSm7 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=lsm7 PE=1 SV=1) HSP 1 Score: 105.145 bits (261), Expect = 1.183e-28 Identity = 53/96 (55.21%), Postives = 68/96 (70.83%), Query Frame = 3 Query: 150 EKKRKETIIDLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTRDLGLVVCKGPTVEVIFPSDGMEPISNPFVDT 437 E+ RKE+I+DLS Y D+RI+ F GGR+++GILKG D L+N+VLD E LR+PED K+T R LGLVV +G T+ +I P DG E I NPFV Sbjct: 18 ERPRKESILDLSRYQDQRIQATFTGGRQITGILKGFDQLMNLVLDDVEEQLRNPEDG-KLTGAIRKLGLVVVRGTTLVLIAPMDGSEEIPNPFVQA 112
BLAST of Sm domain-containing protein vs. UniProt/SwissProt
Match: sp|Q54HF6|LSM7_DICDI (Probable U6 snRNA-associated Sm-like protein LSm7 OS=Dictyostelium discoideum OX=44689 GN=lsm7 PE=3 SV=1) HSP 1 Score: 100.908 bits (250), Expect = 3.485e-27 Identity = 48/90 (53.33%), Postives = 65/90 (72.22%), Query Frame = 3 Query: 159 RKETIIDLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTRDLGLVVCKGPTVEVIFPSDGMEPISNPF 428 +KE+I+DL ++ K I VKF GGREV GILKG D L+N+ LD T E++RD ED T+ R LGLVVC+G +V ++ P++G EPI NP+ Sbjct: 8 KKESILDLQKFLGKEICVKFTGGREVQGILKGYDQLVNITLDQTQEFIRDAEDPLITTDEKRFLGLVVCRGSSVMMVCPTEGCEPIDNPY 97
BLAST of Sm domain-containing protein vs. TrEMBL
Match: A0A183APX9 (Sm domain-containing protein OS=Echinostoma caproni OX=27848 GN=ECPE_LOCUS9015 PE=4 SV=1) HSP 1 Score: 152.525 bits (384), Expect = 4.676e-45 Identity = 69/94 (73.40%), Postives = 85/94 (90.43%), Query Frame = 3 Query: 150 EKKRKETIIDLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTRDLGLVVCKGPTVEVIFPSDGMEPISNPFV 431 EK+RKE+IIDLS Y+DKRIRVKF+GGRE +GILKGCD L NMVLD TTEYLRDP+D ++TE+TR+LGLVVC+GP+VE++ P+DGME I+NPFV Sbjct: 9 EKRRKESIIDLSKYLDKRIRVKFSGGREATGILKGCDNLQNMVLDCTTEYLRDPDDPHRLTEDTRELGLVVCRGPSVELVCPADGMEAIANPFV 102
BLAST of Sm domain-containing protein vs. TrEMBL
Match: A0A0X3P1A4 (U6 snRNA-associated Sm-like protein LSm7 OS=Schistocephalus solidus OX=70667 GN=LSM7 PE=4 SV=1) HSP 1 Score: 150.599 bits (379), Expect = 2.634e-44 Identity = 68/96 (70.83%), Postives = 85/96 (88.54%), Query Frame = 3 Query: 150 EKKRKETIIDLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTRDLGLVVCKGPTVEVIFPSDGMEPISNPFVDT 437 EKKRKE+IIDLS Y+DKRIRVKF GGRE +GILKGCD L NMVLD TTEYLR+P+D ++++E+TR+LGLVVC+GP+VE++ P+DGME I+NPF T Sbjct: 9 EKKRKESIIDLSKYLDKRIRVKFTGGREATGILKGCDNLQNMVLDNTTEYLREPDDPSRLSEDTRELGLVVCRGPSVELVCPADGMEAIANPFAQT 104
BLAST of Sm domain-containing protein vs. TrEMBL
Match: A0A3P7PVA9 (Sm domain-containing protein OS=Dibothriocephalus latus OX=60516 GN=DILT_LOCUS14315 PE=4 SV=1) HSP 1 Score: 149.828 bits (377), Expect = 7.285e-44 Identity = 67/94 (71.28%), Postives = 84/94 (89.36%), Query Frame = 3 Query: 150 EKKRKETIIDLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTRDLGLVVCKGPTVEVIFPSDGMEPISNPFV 431 EKKRKE+IIDLS Y+DKRIRVKF GGRE +GILKGCD L NMVLD TTEYLR+P+D ++++E+TR+LGLVVC+GP+VE++ P+DGME I+NPF Sbjct: 9 EKKRKESIIDLSKYLDKRIRVKFTGGREATGILKGCDNLQNMVLDNTTEYLREPDDPSRLSEDTRELGLVVCRGPSVELVCPADGMEAIANPFA 102
BLAST of Sm domain-containing protein vs. TrEMBL
Match: A0A0R3UPV9 (Sm domain-containing protein OS=Mesocestoides corti OX=53468 GN=MCOS_LOCUS9897 PE=4 SV=1) HSP 1 Score: 146.747 bits (369), Expect = 1.249e-42 Identity = 67/104 (64.42%), Postives = 89/104 (85.58%), Query Frame = 3 Query: 120 MAANKDKLSFEKKRKETIIDLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTRDLGLVVCKGPTVEVIFPSDGMEPISNPFV 431 M+ ++ + + ++ +KE+IIDL+ Y+DKRIRVKF GGRE +GILKGCD L NMVLD T EYLRDPED T++TE++R+LGLVVC+GP+VE++ P+DGME ISNPFV Sbjct: 1 MSGDQQQTT-KRPKKESIIDLTRYLDKRIRVKFTGGREATGILKGCDNLQNMVLDNTIEYLRDPEDHTRLTEDSRELGLVVCRGPSVELVCPADGMEAISNPFV 103
BLAST of Sm domain-containing protein vs. TrEMBL
Match: A0A4S2M725 (Sm domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_002214 PE=4 SV=1) HSP 1 Score: 145.591 bits (366), Expect = 2.782e-42 Identity = 65/94 (69.15%), Postives = 84/94 (89.36%), Query Frame = 3 Query: 150 EKKRKETIIDLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTRDLGLVVCKGPTVEVIFPSDGMEPISNPFV 431 EK+RKE+IIDL+ Y+DK+IRVKF+GGRE +GILKGCD L NMVLD TTE+LRDP+D +++E+TR+LGLVVC+GP+VE++ P+DGME I NPFV Sbjct: 9 EKRRKESIIDLNKYLDKKIRVKFSGGREATGILKGCDNLQNMVLDCTTEFLRDPDDPHRLSEDTRELGLVVCRGPSVELVCPADGMEAIPNPFV 102
BLAST of Sm domain-containing protein vs. Ensembl Cavefish
Match: lsm7 (LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated [Source:NCBI gene;Acc:103032086]) HSP 1 Score: 135.961 bits (341), Expect = 5.711e-42 Identity = 65/94 (69.15%), Postives = 76/94 (80.85%), Query Frame = 3 Query: 150 EKKRKETIIDLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTRDLGLVVCKGPTVEVIFPSDGMEPISNPFV 431 EKK+KE+I DLS YIDK IRVKF GGRE SG+LKG DPLLN+VLD T EY+RDP+D K+TE+TR LGLVVC+G V +I P DGME I NPF+ Sbjct: 5 EKKKKESIFDLSKYIDKPIRVKFQGGREASGVLKGFDPLLNLVLDGTIEYMRDPDDQYKLTEDTRQLGLVVCRGTAVVLICPQDGMEAIPNPFI 98
BLAST of Sm domain-containing protein vs. Ensembl Cavefish
Match: snrpg (small nuclear ribonucleoprotein polypeptide G [Source:NCBI gene;Acc:107196920]) HSP 1 Score: 44.669 bits (104), Expect = 1.061e-6 Identity = 24/68 (35.29%), Postives = 41/68 (60.29%), Query Frame = 3 Query: 177 DLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTRDLGLVVCKGPTV 380 +L ++DK++ +K GGR V GIL+G DP +N+V+D E + +NT +G+VV +G ++ Sbjct: 8 ELKKFMDKKLSLKLNGGRHVQGILRGFDPFMNLVVDDCLEM------SPGGQQNT--IGMVVIRGNSI 67
BLAST of Sm domain-containing protein vs. Ensembl Cavefish
Match: snrpg (small nuclear ribonucleoprotein polypeptide G [Source:NCBI gene;Acc:107196920]) HSP 1 Score: 43.5134 bits (101), Expect = 4.035e-6 Identity = 18/40 (45.00%), Postives = 28/40 (70.00%), Query Frame = 3 Query: 177 DLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTE 296 +L ++DK++ +K GGR V GIL+G DP +N+V+D E Sbjct: 8 ELKKFMDKKLSLKLNGGRHVQGILRGFDPFMNLVVDDCLE 47
BLAST of Sm domain-containing protein vs. Ensembl Sea Lamprey
Match: snrpg (small nuclear ribonucleoprotein polypeptide G [Source:ZFIN;Acc:ZDB-GENE-040912-105]) HSP 1 Score: 42.3578 bits (98), Expect = 1.710e-6 Identity = 23/68 (33.82%), Postives = 41/68 (60.29%), Query Frame = 3 Query: 177 DLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTRDLGLVVCKGPTV 380 +L ++DK++ +K G R V+GIL+G DP +N+V+D E + +N D+G+VV +G ++ Sbjct: 8 ELKKFMDKKLSLKLNGSRTVTGILRGFDPFMNLVMDECFELCQGG------VQN--DVGMVVIRGNSI 67
BLAST of Sm domain-containing protein vs. Ensembl Yeast
Match: LSM7 (Lsm (Like Sm) protein; part of heteroheptameric complexes (Lsm2p-7p and either Lsm1p or 8p): cytoplasmic Lsm1p complex involved in mRNA decay; nuclear Lsm8p complex part of U6 snRNP and possibly involved in processing tRNA, snoRNA, and rRNA; protein abundance increases and forms cytoplasmic foci in response to DNA replication stress [Source:SGD;Acc:S000005091]) HSP 1 Score: 79.7221 bits (195), Expect = 1.442e-20 Identity = 39/89 (43.82%), Postives = 58/89 (65.17%), Query Frame = 3 Query: 147 FEKKRKETIIDLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATK---ITENTRDLGLVVCKGPTVEVIFPSDG 404 FE ++E I+DL+ Y D +IRVK GG+ V G+LKG D L+N+VLD T EY+ +P+D I++N R LGL V +G + + ++G Sbjct: 19 FEGPKREAILDLAKYKDSKIRVKLMGGKLVIGVLKGYDQLMNLVLDDTVEYMSNPDDENNTELISKNARKLGLTVIRGTILVSLSSAEG 107
BLAST of Sm domain-containing protein vs. Ensembl Yeast
Match: SMX2 (Core Sm protein Sm G; part of heteroheptameric complex (with Smb1p, Smd1p, Smd2p, Smd3p, Sme1p, and Smx3p) that is part of the spliceosomal U1, U2, U4, and U5 snRNPs; homolog of human Sm G [Source:SGD;Acc:S000002965]) HSP 1 Score: 40.0466 bits (92), Expect = 7.501e-6 Identity = 26/65 (40.00%), Postives = 37/65 (56.92%), Query Frame = 3 Query: 189 YIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTRDLGL-VVCKGPTV 380 Y+DK+I + G R+V+GIL+G D LN+VLD E + ED N LGL V +G ++ Sbjct: 10 YMDKKILLNINGSRKVAGILRGYDIFLNVVLDDAMEI--NGEDPA----NNHQLGLQTVIRGNSI 68
BLAST of Sm domain-containing protein vs. Ensembl Nematostella
Match: EDO41002 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S5M5]) HSP 1 Score: 125.176 bits (313), Expect = 3.805e-38 Identity = 58/96 (60.42%), Postives = 75/96 (78.12%), Query Frame = 3 Query: 144 SFEKKRKETIIDLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTRDLGLVVCKGPTVEVIFPSDGMEPISNPFV 431 S E+K K++I DLS ++DK +RVKF GGRE SG+LKG D LLN+VLD T EYLRDP+D K+++ TR LGLVVC+G V ++ P DGME I+NPF+ Sbjct: 3 SGERKEKKSIFDLSKFLDKGVRVKFQGGREASGVLKGFDALLNLVLDNTIEYLRDPDDPLKLSDETRQLGLVVCRGTAVVLVCPMDGMEAIANPFI 98
BLAST of Sm domain-containing protein vs. Ensembl Nematostella
Match: EDO48813 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RII4]) HSP 1 Score: 50.8322 bits (120), Expect = 2.355e-9 Identity = 25/68 (36.76%), Postives = 40/68 (58.82%), Query Frame = 3 Query: 177 DLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTRDLGLVVCKGPTV 380 +L Y+DK++ +K GGR VSG+L+G DP +N+VLD E + E +G+VV +G ++ Sbjct: 8 ELKKYMDKKLSLKLNGGRHVSGVLRGYDPFMNLVLDDAVENVSGNEKHA--------IGMVVIRGNSI 67
BLAST of Sm domain-containing protein vs. Ensembl Medaka
Match: lsm7 (LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated [Source:NCBI gene;Acc:101175386]) HSP 1 Score: 136.732 bits (343), Expect = 3.586e-42 Identity = 65/94 (69.15%), Postives = 77/94 (81.91%), Query Frame = 3 Query: 150 EKKRKETIIDLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTRDLGLVVCKGPTVEVIFPSDGMEPISNPFV 431 EKK+KE+I DLS YIDK IRVKF GGRE SG+LKG DPLLN+VLD T EY+RDP+D K+TE+TR LGLVVC+G +V +I P DGME I NPF+ Sbjct: 5 EKKKKESIFDLSKYIDKPIRVKFQGGREASGVLKGFDPLLNLVLDGTIEYMRDPDDQLKLTEDTRQLGLVVCRGTSVVLICPQDGMEAIPNPFI 98
BLAST of Sm domain-containing protein vs. Ensembl Medaka
Match: lsm7 (LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated [Source:NCBI gene;Acc:101175386]) HSP 1 Score: 136.732 bits (343), Expect = 6.080e-42 Identity = 65/94 (69.15%), Postives = 77/94 (81.91%), Query Frame = 3 Query: 150 EKKRKETIIDLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTRDLGLVVCKGPTVEVIFPSDGMEPISNPFV 431 EKK+KE+I DLS YIDK IRVKF GGRE SG+LKG DPLLN+VLD T EY+RDP+D K+TE+TR LGLVVC+G +V +I P DGME I NPF+ Sbjct: 26 EKKKKESIFDLSKYIDKPIRVKFQGGREASGVLKGFDPLLNLVLDGTIEYMRDPDDQLKLTEDTRQLGLVVCRGTSVVLICPQDGMEAIPNPFI 119
BLAST of Sm domain-containing protein vs. Ensembl Medaka
Match: snrpg (small nuclear ribonucleoprotein polypeptide G [Source:NCBI gene;Acc:101154947]) HSP 1 Score: 45.4394 bits (106), Expect = 7.017e-7 Identity = 24/68 (35.29%), Postives = 40/68 (58.82%), Query Frame = 3 Query: 177 DLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTRDLGLVVCKGPTV 380 +L ++DK++ +K GGR V GIL+G DP +N+V+D E +NT +G+VV +G ++ Sbjct: 8 ELKKFMDKKLSLKLNGGRHVQGILRGFDPFMNLVMDDCLEM------GPGGQQNT--IGMVVIRGNSI 67
BLAST of Sm domain-containing protein vs. Ensembl Medaka
Match: snrpg (small nuclear ribonucleoprotein polypeptide G [Source:NCBI gene;Acc:101154947]) HSP 1 Score: 45.0542 bits (105), Expect = 1.611e-6 Identity = 17/36 (47.22%), Postives = 27/36 (75.00%), Query Frame = 3 Query: 177 DLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLD 284 +L ++DK++ +K GGR V GIL+G DP +N+V+D Sbjct: 8 ELKKFMDKKLSLKLNGGRHVQGILRGFDPFMNLVMD 43
BLAST of Sm domain-containing protein vs. Planmine SMEST
Match: SMESG000081731.1 (SMESG000081731.1) HSP 1 Score: 46.9802 bits (110), Expect = 1.125e-7 Identity = 23/75 (30.67%), Postives = 43/75 (57.33%), Query Frame = 3 Query: 177 DLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTRDLGLVVCKGPTVEVIFPSD 401 +L Y+DKR+ +K G R V GI++G DP +N+VL+ E +D ++ ++G +V +G ++ ++ D Sbjct: 8 ELKKYMDKRMTLKLNGHRRVKGIMRGFDPFMNIVLENAVEIDKDNQEV--------NIGTIVIRGNSISILEAVD 74
BLAST of Sm domain-containing protein vs. Planmine SMEST
Match: SMESG000081727.1 (SMESG000081727.1) HSP 1 Score: 46.9802 bits (110), Expect = 1.125e-7 Identity = 23/75 (30.67%), Postives = 43/75 (57.33%), Query Frame = 3 Query: 177 DLSIYIDKRIRVKFAGGREVSGILKGCDPLLNMVLDVTTEYLRDPEDATKITENTRDLGLVVCKGPTVEVIFPSD 401 +L Y+DKR+ +K G R V GI++G DP +N+VL+ E +D ++ ++G +V +G ++ ++ D Sbjct: 8 ELKKYMDKRMTLKLNGHRRVKGIMRGFDPFMNIVLENAVEIDKDNQEV--------NIGTIVIRGNSISILEAVD 74 The following BLAST results are available for this feature:
BLAST of Sm domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Sm domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 2
BLAST of Sm domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Sm domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 3
BLAST of Sm domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 4
BLAST of Sm domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 3
BLAST of Sm domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Sm domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Sm domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 3
BLAST of Sm domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 1
BLAST of Sm domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 2
BLAST of Sm domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 2
BLAST of Sm domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 4
BLAST of Sm domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 2
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30019973 ID=SMED30019973|Name=Sm domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=473bpback to top protein sequence of SMED30019973-orf-1 >SMED30019973-orf-1 ID=SMED30019973-orf-1|Name=SMED30019973-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=109bp MAANKDKLSFEKKRKETIIDLSIYIDKRIRVKFAGGREVSGILKGCDPLLback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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