Roc domain-containing protein
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30019942 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 6
Homology
BLAST of Roc domain-containing protein vs. Ensembl Human
Match: SHOC2 (SHOC2 leucine rich repeat scaffold protein [Source:HGNC Symbol;Acc:HGNC:15454]) HSP 1 Score: 84.3445 bits (207), Expect = 4.097e-16 Identity = 108/395 (27.34%), Postives = 201/395 (50.89%), Query Frame = 3
Query: 180 RDARKNNEDDFKSINLSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDSNMESLLQSGQILSDHISNTIFDL-----PA----VQAVEMEFCKINY--FKSF-QSKALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISLDYYNKSLETLKXXXXXXXXXXXXXXYLEKLENLDVSSNNISELPLDLCLMKNIK 1328
++ K E++ ++LS ++ ++P ++ + ++T L + N ++SLPA++ LVNL L +S N +T LP S+ NLK L+ L++ L IP+ ++ + SL L + N I + DI NL +L L+ + +K LP EI L L L N + IP LA +L+ L++ ++ +S + SL++ + ++ F L P+ + ++ ME +IN F F ++K L +L++ N +P ++ L+L+ N L I +D+ L +L L L N ++K+ L ++ L+ LDL NK++ L + Y K L+ L + +N + +P I +L L +L + N ++ LP ++ ++N++
Sbjct: 92 KELNKCREENSMRLDLSKRSIHILPSSIKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSEN--------SLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLLSSLVKLNSL---TLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNEIAYL-KDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIGTLENLE 474 HSP 2 Score: 55.4546 bits (132), Expect = 4.613e-7 Identity = 58/218 (26.61%), Postives = 98/218 (44.95%), Query Frame = 3
Query: 216 SINLSNTALTVVPVTLFKRIEI-THLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWL------------------NAQHCGLKT-----LPQEIVGCEKLETLLLYGNV-IQTIPYLLADIGSLKTLSIN---LRHLGEKIDSNMESLL 785
S+N+ + + +P +F R ++ + LN+ +N + SLP D ++ LN++ N +T +P+ + L L+ L +S L +P + + L +LD+ +N + L ++I L LQ L N H GL LP+EI E LE L L N + ++P+ LA L +SI L HL +I + S +
Sbjct: 313 SLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATN--------QLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDNPNLHSLPFELALCSKLSIMSIENCPLSHLPPQIVAGGPSFI 522
BLAST of Roc domain-containing protein vs. Ensembl Human
Match: LRRC7 (leucine rich repeat containing 7 [Source:HGNC Symbol;Acc:HGNC:18531]) HSP 1 Score: 82.4185 bits (202), Expect = 3.884e-15 Identity = 82/321 (25.55%), Postives = 144/321 (44.86%), Query Frame = 3
Query: 219 INLSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDSNMESLLQSGQILSDHISNTIFDLPAVQAVEMEFCKINYFKSFQS-----KALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISL 1166
I S ++ +P + + +T L +++ ++ LPA+ LV L +L + N + LPKSM L L+ L++ +P + +I +L +L + N + L IG L L +L+ ++T+ +I GCE LE LLL N++Q +P + + L TL K+D N ++L NTI +L ++ + C N +S S +L L + NF E+P + + N+T + L+ N++E + + + QM+ L+VL+LS N++K L S
Sbjct: 125 IEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELREN--------HLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTL---------KVDDNQLTML----------PNTIGNLSLLEEFD---CSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGSCK-----------------------NVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSDNRLKNLPFSF 392
BLAST of Roc domain-containing protein vs. Ensembl Human
Match: LRRC7 (leucine rich repeat containing 7 [Source:HGNC Symbol;Acc:HGNC:18531]) HSP 1 Score: 82.0333 bits (201), Expect = 4.672e-15 Identity = 82/321 (25.55%), Postives = 144/321 (44.86%), Query Frame = 3
Query: 219 INLSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDSNMESLLQSGQILSDHISNTIFDLPAVQAVEMEFCKINYFKSFQS-----KALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISL 1166
I S ++ +P + + +T L +++ ++ LPA+ LV L +L + N + LPKSM L L+ L++ +P + +I +L +L + N + L IG L L +L+ ++T+ +I GCE LE LLL N++Q +P + + L TL K+D N ++L NTI +L ++ + C N +S S +L L + NF E+P + + N+T + L+ N++E + + + QM+ L+VL+LS N++K L S
Sbjct: 158 IEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELREN--------HLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTL---------KVDDNQLTML----------PNTIGNLSLLEEFD---CSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGSCK-----------------------NVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSDNRLKNLPFSF 425
BLAST of Roc domain-containing protein vs. Ensembl Human
Match: LRRIQ4 (leucine rich repeats and IQ motif containing 4 [Source:HGNC Symbol;Acc:HGNC:34298]) HSP 1 Score: 80.8777 bits (198), Expect = 5.145e-15 Identity = 99/428 (23.13%), Postives = 190/428 (44.39%), Query Frame = 3
Query: 210 FKSINLSNTALTVVPVTLFKRIE-ITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDSNMESL--LQSGQILSDHISNTIFDLPAVQAVEMEFCKINYFKSFQSK-----ALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTL---YLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISLDYYNKSLETLKXXXXXXXXXXXXXXYLEKLENLDVSSNNISELPLDLCLMKNIKTAHYFNGLHRIGLWVSSNPIEFPPKCVWNTTNIDVIYSFLQKTK 1460
+ + L T L +PV +FK + + L ++ N++K LP +I + L + + RN F + P+ + L L+ +++ E + IP I +T L + ++ NN+ L + + QL L+ H L ++P+ K+ + L GN ++ +P L+ SL L + L ++ + L L+ + +H+ + + A++ +E+ N S+ L L ++GN F PE VL+L +L+ L + ++ + + L +L Y++ N +E + SL M +L+VLD HN +K+L ++ + L+ L + N ++ LP +L + N+K L + NP+E PPK V N + I+ +L++ +
Sbjct: 120 LRELRLYQTDLKEIPVVIFKNLHHLELLGLTGNHLKCLPKEIVNQTKLREIYLKRNQFE--------VFPQELCVLYTLEIIDLDENKIGAIPEEIGHLTGLQKFYMASNNLPVLPASLCQCSQLSVLDLSHNLLHSIPKSFAELRKMTEIGLSGNRLEKVPRLICRWTSLHLLYLGNTGL-HRLRGSFRCLVNLRFLDLSQNHLHHCPLQICALKNLEVLGLDDNKIGQLPSELGSLSKLKILGLTGNEFLSFPEEVLSLASLEKLYIGQDQGFKLTYVPEHIRKLQSLKELYIENNHLEYLPVSLGSMPNLEVLDCRHNLLKQLPDAI------------------------CQAQALKELRLEDNLLTHLPENLDSLVNLKV-----------LTLMDNPMEEPPKEVCAEGN-EAIWKYLKENR 502
BLAST of Roc domain-containing protein vs. Ensembl Human
Match: ERBIN (erbb2 interacting protein [Source:HGNC Symbol;Acc:HGNC:15842]) HSP 1 Score: 80.1073 bits (196), Expect = 1.078e-14 Identity = 53/166 (31.93%), Postives = 92/166 (55.42%), Query Frame = 3
Query: 240 LTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSIN 737
LT +P + ++T+L+VS+NNI+ + IS NL+ L +S N + LP+++ +LK + L I E L+++P +I + S+ +LD S N + L S IG L L+ A H L+ LP EI + + L L+ N ++T+P + D+ LK ++++
Sbjct: 219 LTFIPGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSN--------SLQQLPETIGSLKNITTLKIDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSIGQLTNLRTFAADHNYLQQLPPEIGSWKNITVLFLHSNKLETLPEEMGDMQKLKVINLS 376 HSP 2 Score: 75.485 bits (184), Expect = 3.065e-13 Identity = 73/318 (22.96%), Postives = 145/318 (45.60%), Query Frame = 3
Query: 219 INLSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDSNMESLLQSGQILSDHISNTIFDLPAVQAVEMEFCKINYFKS--FQSKALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISL 1166
+ S ++ +P + + +T L +++ ++ LPA+ L L++L + N + +LPK+M L L+ L++ +P + +++ L + + N + + IG+L QL +L+ ++ + + I CE L+ LLL N +Q +P IGSLK ++ KID N Q++ ++ ++I L +V+ ++ F ++ S Q L N+ Q++P + + N+T L+L N++E + + + M+ LKV++LS N++K L S
Sbjct: 120 VEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFGRLTKLQILELREN--------QLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFIPGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSLQQLP---ETIGSLKNITT------LKIDEN--------QLM--YLPDSIGGLISVEELDCSFNEVEALPSSIGQLTNLRTFAADHNYLQQLPPEIGSWK-----------------------NITVLFLHSNKLETLPEEMGDMQKLKVINLSDNRLKNLPFSF 387
BLAST of Roc domain-containing protein vs. Ensembl Celegans
Match: let-413 (pep chromosome:WBcel235:V:7972924:7977774:-1 gene:WBGene00002632.1 transcript:F26D11.11a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:let-413) HSP 1 Score: 85.1149 bits (209), Expect = 1.285e-16 Identity = 100/369 (27.10%), Postives = 180/369 (48.78%), Query Frame = 3
Query: 216 SINLSNTALTVVPVTLFKRIEITHLNVSENNIKSL-----------------------PADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDS----NM---------------ESLLQSGQILSDHIS-NTIFDLPA----VQAVEMEFCKINYFKSFQS-----KALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISL 1166
SI+ S + L +P +F+ ++ LN++ NNIK L PA+I +L L LN++RN + LP +M+N K L LN+S +P TI E +S+ L +++ ++ L S+IG+L L+ L A+ L+T+P IV KLE L L N ++ +P + + SL+ +++ L DS M E+L + + +IS N I +LP+ ++ ++M N + S ++L EL++ NF ++P+T+ +L L L++ N L +I D + ++LT L L+ N + ++ ++ + ++L VLD++ NK+ L ++
Sbjct: 17 SIDRSQSNLQAIPSDIFRFRKLEDLNLTMNNIKELDHRLFSLRHLRILDVSDNELAVLPAEIGNLTQLIELNLNRNS--------IAKLPDTMQNCKLLTTLNLSSNPFTRLPETICECSSITILSLNETSLTLLPSNIGSLTNLRVLEARDNLLRTIPLSIVELRKLEELDLGQNELEALPAEIGKLTSLREFYVDINSLTSLPDSISGCRMLDQLDVSENQIIRLPENLGRMPNLTDLNISINEIIELPSSFGELKRLQMLKADRNSLHNLTSEIGKCQSLTELYLGQNFLTDLPDTIGDLRQLTTLNVDCNNLSDIPDTIGNCKSLTVLSLRQNILTELPMTIGKCENLTVLDVASNKLPHLPFTV 377 HSP 2 Score: 56.6102 bits (135), Expect = 8.334e-8 Identity = 54/218 (24.77%), Postives = 98/218 (44.95%), Query Frame = 3
Query: 219 INLSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDSNMESLLQSGQILSDHIS---NTIFDLPAVQAVEME 863
+++S + +P L + +T LN+S N I LP+ +L L++L RN H L + + L L + + L +P TI ++ L L++ NN+ ++ IGN L L+ + L LP I CE L L + N + +P+ + + L+ L ++ ++ +S+L+ + D T + LP V A++ E
Sbjct: 225 LDVSENQIIRLPENLGRMPNLTDLNISINEIIELPSSFGELKRLQMLKADRNSLHN--------LTSEIGKCQSLTELYLGQNFLTDLPDTIGDLRQLTTLNVDCNNLSDIPDTIGNCKSLTVLSLRQNILTELPMTIGKCENLTVLDVASNKLPHLPFTVKVLYKLQALWLS--------ENQTQSILKLSETRDDRKGIKVVTCYLLPQVDAIDGE 426 HSP 3 Score: 55.0694 bits (131), Expect = 2.425e-7 Identity = 88/348 (25.29%), Postives = 169/348 (48.56%), Query Frame = 3
Query: 276 EITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDSNMESL-----LQSGQILSDHISNTIFDLPAVQAVEMEFCKINYFKSFQSK--ALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISLDYYNKSLETLKXXXXXXXXXXXXXXYLEKLENLDVSSNNISELP 1298
++ ++ S++N++++P+DI LE LN++ M N+K L + ++ + L LD+S N + L ++IGNL QL LN + LP + C+ L TL L N +P + + S+ LS+N L + SN+ SL L++ L I +I +L ++ +++ ++ + K +L E ++ N +P+++ L LD+S+N ++ + ++L ++ NLT L + N+I ++ S ++K L++L N + LT + +SL L + N + ++P+ I L +L L+V NN+S++P
Sbjct: 14 QVDSIDRSQSNLQAIPSDIFRFRKLEDLNLT------------------MNNIKELDH-------------RLFSLRHLRILDVSDNELAVLPAEIGNLTQLIELNLNRNSIAKLPDTMQNCKLLTTLNLSSNPFTRLPETICECSSITILSLNETSL-TLLPSNIGSLTNLRVLEARDNLLRTIPLSIVELRKLEELDLGQNELEALPAEIGKLTSLREFYVDINSLTSLPDSISGCRMLDQLDVSENQIIRLPENLGRMPNLTDLNISINEIIELPSSFGELKRLQMLKADRNSLHNLTSEIGKC-QSLTELYLGQNFLTDLPDTIGDLRQLTTLNVDCNNLSDIP 328
BLAST of Roc domain-containing protein vs. Ensembl Celegans
Match: let-413 (pep chromosome:WBcel235:V:7972934:7977774:-1 gene:WBGene00002632.1 transcript:F26D11.11b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:let-413) HSP 1 Score: 84.7297 bits (208), Expect = 1.562e-16 Identity = 94/331 (28.40%), Postives = 169/331 (51.06%), Query Frame = 3
Query: 261 LFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDS----NM---------------ESLLQSGQILSDHIS-NTIFDLPA----VQAVEMEFCKINYFKSFQS-----KALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISL 1166
LF + L+VS+N + LPA+I +L L LN++RN + LP +M+N K L LN+S +P TI E +S+ L +++ ++ L S+IG+L L+ L A+ L+T+P IV KLE L L N ++ +P + + SL+ +++ L DS M E+L + + +IS N I +LP+ ++ ++M N + S ++L EL++ NF ++P+T+ +L L L++ N L +I D + ++LT L L+ N + ++ ++ + ++L VLD++ NK+ L ++
Sbjct: 55 LFSLRHLRILDVSDNELAVLPAEIGNLTQLIELNLNRNS--------IAKLPDTMQNCKLLTTLNLSSNPFTRLPETICECSSITILSLNETSLTLLPSNIGSLTNLRVLEARDNLLRTIPLSIVELRKLEELDLGQNELEALPAEIGKLTSLREFYVDINSLTSLPDSISGCRMLDQLDVSENQIIRLPENLGRMPNLTDLNISINEIIELPSSFGELKRLQMLKADRNSLHNLTSEIGKCQSLTELYLGQNFLTDLPDTIGDLRQLTTLNVDCNNLSDIPDTIGNCKSLTVLSLRQNILTELPMTIGKCENLTVLDVASNKLPHLPFTV 377 HSP 2 Score: 56.6102 bits (135), Expect = 8.671e-8 Identity = 45/170 (26.47%), Postives = 78/170 (45.88%), Query Frame = 3
Query: 219 INLSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTL 728
+++S + +P L + +T LN+S N I LP+ +L L++L RN H L + + L L + + L +P TI ++ L L++ NN+ ++ IGN L L+ + L LP I CE L L + N + +P+ + + L+ L
Sbjct: 225 LDVSENQIIRLPENLGRMPNLTDLNISINEIIELPSSFGELKRLQMLKADRNSLHN--------LTSEIGKCQSLTELYLGQNFLTDLPDTIGDLRQLTTLNVDCNNLSDIPDTIGNCKSLTVLSLRQNILTELPMTIGKCENLTVLDVASNKLPHLPFTVKVLYKLQAL 386 HSP 3 Score: 54.6842 bits (130), Expect = 3.042e-7 Identity = 88/348 (25.29%), Postives = 169/348 (48.56%), Query Frame = 3
Query: 276 EITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDSNMESL-----LQSGQILSDHISNTIFDLPAVQAVEMEFCKINYFKSFQSK--ALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISLDYYNKSLETLKXXXXXXXXXXXXXXYLEKLENLDVSSNNISELP 1298
++ ++ S++N++++P+DI LE LN++ M N+K L + ++ + L LD+S N + L ++IGNL QL LN + LP + C+ L TL L N +P + + S+ LS+N L + SN+ SL L++ L I +I +L ++ +++ ++ + K +L E ++ N +P+++ L LD+S+N ++ + ++L ++ NLT L + N+I ++ S ++K L++L N + LT + +SL L + N + ++P+ I L +L L+V NN+S++P
Sbjct: 14 QVDSIDRSQSNLQAIPSDIFRFRKLEDLNLT------------------MNNIKELDH-------------RLFSLRHLRILDVSDNELAVLPAEIGNLTQLIELNLNRNSIAKLPDTMQNCKLLTTLNLSSNPFTRLPETICECSSITILSLNETSL-TLLPSNIGSLTNLRVLEARDNLLRTIPLSIVELRKLEELDLGQNELEALPAEIGKLTSLREFYVDINSLTSLPDSISGCRMLDQLDVSENQIIRLPENLGRMPNLTDLNISINEIIELPSSFGELKRLQMLKADRNSLHNLTSEIGKC-QSLTELYLGQNFLTDLPDTIGDLRQLTTLNVDCNNLSDIP 328
BLAST of Roc domain-containing protein vs. Ensembl Celegans
Match: Y42G9A.3 (pep chromosome:WBcel235:III:6146214:6148065:1 gene:WBGene00021533.1 transcript:Y42G9A.3b.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y42G9A.3) HSP 1 Score: 67.3958 bits (163), Expect = 8.387e-12 Identity = 68/242 (28.10%), Postives = 121/242 (50.00%), Query Frame = 3
Query: 201 EDDF-----KSINLSNTALTVV-PVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSIN---LRHLGEKIDSNMESL----LQSGQILSDHISNTIFDLPAVQAVEMEFCKINYFK 887
E+D+ K ++L++ + ++ +T F + + L+VS N++ +LP DI L +L L I+RN + LPK ++ L+ L++L +S L ++P I + L L + N I S+I L L+ L L+ +P I ++LE L L N+++TIP L D+ L+TLS++ LR L I N+ L L++ ++ + N P+++ + + NY K
Sbjct: 55 EEDYDPQNVKKLDLTHNSFVILRGLTTFNNVSV--LDVSFNSLSALPEDIGTLSSLTTL-IARNNL-------LEHLPKGLQLLENLEHLYLSGNRLEYVPPVILTMRKLKTLHLGGNYIDSCPSNISVLTLLRVLYLGGNRLREIPASIGCLDELENLGLCDNILETIPSTLGDLHYLETLSLHNNRLRTLPTDI-LNLRRLQQLSLRNNPLVHSFVHNMDLAPPSLKELSGRTVRQNYHK 285
BLAST of Roc domain-containing protein vs. Ensembl Celegans
Match: Y42G9A.3 (pep chromosome:WBcel235:III:6146266:6148065:1 gene:WBGene00021533.1 transcript:Y42G9A.3b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y42G9A.3) HSP 1 Score: 67.3958 bits (163), Expect = 8.387e-12 Identity = 68/242 (28.10%), Postives = 121/242 (50.00%), Query Frame = 3
Query: 201 EDDF-----KSINLSNTALTVV-PVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSIN---LRHLGEKIDSNMESL----LQSGQILSDHISNTIFDLPAVQAVEMEFCKINYFK 887
E+D+ K ++L++ + ++ +T F + + L+VS N++ +LP DI L +L L I+RN + LPK ++ L+ L++L +S L ++P I + L L + N I S+I L L+ L L+ +P I ++LE L L N+++TIP L D+ L+TLS++ LR L I N+ L L++ ++ + N P+++ + + NY K
Sbjct: 55 EEDYDPQNVKKLDLTHNSFVILRGLTTFNNVSV--LDVSFNSLSALPEDIGTLSSLTTL-IARNNL-------LEHLPKGLQLLENLEHLYLSGNRLEYVPPVILTMRKLKTLHLGGNYIDSCPSNISVLTLLRVLYLGGNRLREIPASIGCLDELENLGLCDNILETIPSTLGDLHYLETLSLHNNRLRTLPTDI-LNLRRLQQLSLRNNPLVHSFVHNMDLAPPSLKELSGRTVRQNYHK 285
BLAST of Roc domain-containing protein vs. Ensembl Celegans
Match: Y42G9A.3 (pep chromosome:WBcel235:III:6146214:6148065:1 gene:WBGene00021533.1 transcript:Y42G9A.3a.3 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y42G9A.3) HSP 1 Score: 67.0106 bits (162), Expect = 2.353e-11 Identity = 68/242 (28.10%), Postives = 121/242 (50.00%), Query Frame = 3
Query: 201 EDDF-----KSINLSNTALTVV-PVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSIN---LRHLGEKIDSNMESL----LQSGQILSDHISNTIFDLPAVQAVEMEFCKINYFK 887
E+D+ K ++L++ + ++ +T F + + L+VS N++ +LP DI L +L L I+RN + LPK ++ L+ L++L +S L ++P I + L L + N I S+I L L+ L L+ +P I ++LE L L N+++TIP L D+ L+TLS++ LR L I N+ L L++ ++ + N P+++ + + NY K
Sbjct: 55 EEDYDPQNVKKLDLTHNSFVILRGLTTFNNVSV--LDVSFNSLSALPEDIGTLSSLTTL-IARNNL-------LEHLPKGLQLLENLEHLYLSGNRLEYVPPVILTMRKLKTLHLGGNYIDSCPSNISVLTLLRVLYLGGNRLREIPASIGCLDELENLGLCDNILETIPSTLGDLHYLETLSLHNNRLRTLPTDI-LNLRRLQQLSLRNNPLVHSFVHNMDLAPPSLKELSGRTVRQNYHK 285
BLAST of Roc domain-containing protein vs. Ensembl Fly
Match: scrib (gene:FBgn0263289 transcript:FBtr0335521) HSP 1 Score: 74.7146 bits (182), Expect = 3.905e-13 Identity = 86/359 (23.96%), Postives = 153/359 (42.62%), Query Frame = 3
Query: 249 VPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDSNMESLLQSGQILSDHISNTIFDLPAVQAVEMEFCKINYFKSFQSKALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISLDYYNKSLETLKXXXXXXXXXXXXXXYLEKLENLDVSSNNISELPLDLCLMKNI 1325
+P F+ + L +S+N I LP DI + NL L++SRN D+ +P +K+L+ L+ + S + +P+ ++ +L L ++ ++ L +D G+L QL+ L + LK LP+ I KL+ L L N I+ +P L + L L + DH N + LP + K+ Y L +S N +E+P + L +LT L L N +E + + ++ L +L L N++++L +L ++++ L + N + +P I + KL NL+V N + LPL++ N+
Sbjct: 52 LPKNFFRLHRLRKLGLSDNEIGRLPPDIQNFENLVELDVSRN--------DIPDIPDDIKHLQSLQVADFSSNPIPKLPSGFSQLKNLTVLGLNDMSLTTLPADFGSLTQLESLELRENLLKHLPETISQLTKLKRLDLGDNEIEDLPPYLGYLPGLHELWL------------------------DH--NQLQRLPPELGL---LTKLTY-----------LDVSENRLEELPNEISGL-----------------------VSLTDLDLAQNLLEALPDGIAKLSRLTILKLDQNRLQRLNDTLGNC-ENMQELILTENFLSELPASIGQMTKLNNLNVDRNALEYLPLEIGQCANL 338 HSP 2 Score: 71.2478 bits (173), Expect = 4.536e-12 Identity = 51/178 (28.65%), Postives = 92/178 (51.69%), Query Frame = 3
Query: 225 LSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPK----------------SMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADI 710
L + L +P L ++T+L+VSEN ++ LP +IS LV+L L++++N PD + L + ++ N + ++ L ++E L +PA+I ++T L+ L++ +N + L +IG L L+ + LK LP E+ C L L + GN + +PY L ++
Sbjct: 205 LDHNQLQRLPPELGLLTKLTYLDVSENRLEELPNEISGLVSLTDLDLAQNLLEAL-PDGIAKLSRLTILKLDQNRLQRLNDTLGNCENMQELILTENFLSELPASIGQMTKLNNLNVDRNALEYLPLEIGQCANLGVLSLRDNKLKKLPPELGNCTVLHVLDVSGNQLLYLPYSLVNL 381 HSP 3 Score: 71.2478 bits (173), Expect = 5.149e-12 Identity = 77/327 (23.55%), Postives = 144/327 (44.04%), Query Frame = 3
Query: 204 DDFKSI------NLSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDSNMESLLQSGQILSDHISNTIFDLPAVQAVEMEFCKINYFKSFQSKALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISL 1166
DD K + + S+ + +P + +T L +++ ++ +LPAD L LE L + N + LP+++ L LK L++ + + +P + + LH+L + N + L ++G L +L +L+ L+ LP EI G L L L N+++ +P +A + L L ++ L Q L+D + N + + EL ++ NF E+P ++ + L L++ +N L + ++ + NL L L+ N+++K+ L L VLD+S N++ L SL
Sbjct: 100 DDIKHLQSLQVADFSSNPIPKLPSGFSQLKNLTVLGLNDMSLTTLPADFGSLTQLESLELREN--------LLKHLPETISQLTKLKRLDLGDNEIEDLPPYLGYLPGLHELWLDHNQLQRLPPELGLLTKLTYLDVSENRLEELPNEISGLVSLTDLDLAQNLLEALPDGIAKLSRLTILKLDQNRL---------------QRLNDTLGNC-------------------------ENMQELILTENFLSELPASIGQMTKLNNLNVDRNALEYLPLEIGQCANLGVLSLRDNKLKKLPPELGNCTVLHVLDVSGNQLLYLPYSL 378
BLAST of Roc domain-containing protein vs. Ensembl Fly
Match: scrib (gene:FBgn0263289 transcript:FBtr0308630) HSP 1 Score: 74.7146 bits (182), Expect = 3.930e-13 Identity = 86/359 (23.96%), Postives = 153/359 (42.62%), Query Frame = 3
Query: 249 VPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDSNMESLLQSGQILSDHISNTIFDLPAVQAVEMEFCKINYFKSFQSKALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISLDYYNKSLETLKXXXXXXXXXXXXXXYLEKLENLDVSSNNISELPLDLCLMKNI 1325
+P F+ + L +S+N I LP DI + NL L++SRN D+ +P +K+L+ L+ + S + +P+ ++ +L L ++ ++ L +D G+L QL+ L + LK LP+ I KL+ L L N I+ +P L + L L + DH N + LP + K+ Y L +S N +E+P + L +LT L L N +E + + ++ L +L L N++++L +L ++++ L + N + +P I + KL NL+V N + LPL++ N+
Sbjct: 52 LPKNFFRLHRLRKLGLSDNEIGRLPPDIQNFENLVELDVSRN--------DIPDIPDDIKHLQSLQVADFSSNPIPKLPSGFSQLKNLTVLGLNDMSLTTLPADFGSLTQLESLELRENLLKHLPETISQLTKLKRLDLGDNEIEDLPPYLGYLPGLHELWL------------------------DH--NQLQRLPPELGL---LTKLTY-----------LDVSENRLEELPNEISGL-----------------------VSLTDLDLAQNLLEALPDGIAKLSRLTILKLDQNRLQRLNDTLGNC-ENMQELILTENFLSELPASIGQMTKLNNLNVDRNALEYLPLEIGQCANL 338 HSP 2 Score: 71.2478 bits (173), Expect = 4.562e-12 Identity = 51/178 (28.65%), Postives = 92/178 (51.69%), Query Frame = 3
Query: 225 LSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPK----------------SMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADI 710
L + L +P L ++T+L+VSEN ++ LP +IS LV+L L++++N PD + L + ++ N + ++ L ++E L +PA+I ++T L+ L++ +N + L +IG L L+ + LK LP E+ C L L + GN + +PY L ++
Sbjct: 205 LDHNQLQRLPPELGLLTKLTYLDVSENRLEELPNEISGLVSLTDLDLAQNLLEAL-PDGIAKLSRLTILKLDQNRLQRLNDTLGNCENMQELILTENFLSELPASIGQMTKLNNLNVDRNALEYLPLEIGQCANLGVLSLRDNKLKKLPPELGNCTVLHVLDVSGNQLLYLPYSLVNL 381 HSP 3 Score: 71.2478 bits (173), Expect = 5.179e-12 Identity = 77/327 (23.55%), Postives = 144/327 (44.04%), Query Frame = 3
Query: 204 DDFKSI------NLSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDSNMESLLQSGQILSDHISNTIFDLPAVQAVEMEFCKINYFKSFQSKALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISL 1166
DD K + + S+ + +P + +T L +++ ++ +LPAD L LE L + N + LP+++ L LK L++ + + +P + + LH+L + N + L ++G L +L +L+ L+ LP EI G L L L N+++ +P +A + L L ++ L Q L+D + N + + EL ++ NF E+P ++ + L L++ +N L + ++ + NL L L+ N+++K+ L L VLD+S N++ L SL
Sbjct: 100 DDIKHLQSLQVADFSSNPIPKLPSGFSQLKNLTVLGLNDMSLTTLPADFGSLTQLESLELREN--------LLKHLPETISQLTKLKRLDLGDNEIEDLPPYLGYLPGLHELWLDHNQLQRLPPELGLLTKLTYLDVSENRLEELPNEISGLVSLTDLDLAQNLLEALPDGIAKLSRLTILKLDQNRL---------------QRLNDTLGNC-------------------------ENMQELILTENFLSELPASIGQMTKLNNLNVDRNALEYLPLEIGQCANLGVLSLRDNKLKKLPPELGNCTVLHVLDVSGNQLLYLPYSL 378
BLAST of Roc domain-containing protein vs. Ensembl Fly
Match: scrib (gene:FBgn0263289 transcript:FBtr0308634) HSP 1 Score: 74.7146 bits (182), Expect = 3.992e-13 Identity = 86/359 (23.96%), Postives = 153/359 (42.62%), Query Frame = 3
Query: 249 VPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDSNMESLLQSGQILSDHISNTIFDLPAVQAVEMEFCKINYFKSFQSKALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISLDYYNKSLETLKXXXXXXXXXXXXXXYLEKLENLDVSSNNISELPLDLCLMKNI 1325
+P F+ + L +S+N I LP DI + NL L++SRN D+ +P +K+L+ L+ + S + +P+ ++ +L L ++ ++ L +D G+L QL+ L + LK LP+ I KL+ L L N I+ +P L + L L + DH N + LP + K+ Y L +S N +E+P + L +LT L L N +E + + ++ L +L L N++++L +L ++++ L + N + +P I + KL NL+V N + LPL++ N+
Sbjct: 52 LPKNFFRLHRLRKLGLSDNEIGRLPPDIQNFENLVELDVSRN--------DIPDIPDDIKHLQSLQVADFSSNPIPKLPSGFSQLKNLTVLGLNDMSLTTLPADFGSLTQLESLELRENLLKHLPETISQLTKLKRLDLGDNEIEDLPPYLGYLPGLHELWL------------------------DH--NQLQRLPPELGL---LTKLTY-----------LDVSENRLEELPNEISGL-----------------------VSLTDLDLAQNLLEALPDGIAKLSRLTILKLDQNRLQRLNDTLGNC-ENMQELILTENFLSELPASIGQMTKLNNLNVDRNALEYLPLEIGQCANL 338 HSP 2 Score: 71.2478 bits (173), Expect = 4.686e-12 Identity = 51/178 (28.65%), Postives = 92/178 (51.69%), Query Frame = 3
Query: 225 LSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPK----------------SMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADI 710
L + L +P L ++T+L+VSEN ++ LP +IS LV+L L++++N PD + L + ++ N + ++ L ++E L +PA+I ++T L+ L++ +N + L +IG L L+ + LK LP E+ C L L + GN + +PY L ++
Sbjct: 205 LDHNQLQRLPPELGLLTKLTYLDVSENRLEELPNEISGLVSLTDLDLAQNLLEAL-PDGIAKLSRLTILKLDQNRLQRLNDTLGNCENMQELILTENFLSELPASIGQMTKLNNLNVDRNALEYLPLEIGQCANLGVLSLRDNKLKKLPPELGNCTVLHVLDVSGNQLLYLPYSLVNL 381 HSP 3 Score: 71.2478 bits (173), Expect = 5.143e-12 Identity = 77/327 (23.55%), Postives = 144/327 (44.04%), Query Frame = 3
Query: 204 DDFKSI------NLSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDSNMESLLQSGQILSDHISNTIFDLPAVQAVEMEFCKINYFKSFQSKALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISL 1166
DD K + + S+ + +P + +T L +++ ++ +LPAD L LE L + N + LP+++ L LK L++ + + +P + + LH+L + N + L ++G L +L +L+ L+ LP EI G L L L N+++ +P +A + L L ++ L Q L+D + N + + EL ++ NF E+P ++ + L L++ +N L + ++ + NL L L+ N+++K+ L L VLD+S N++ L SL
Sbjct: 100 DDIKHLQSLQVADFSSNPIPKLPSGFSQLKNLTVLGLNDMSLTTLPADFGSLTQLESLELRENL--------LKHLPETISQLTKLKRLDLGDNEIEDLPPYLGYLPGLHELWLDHNQLQRLPPELGLLTKLTYLDVSENRLEELPNEISGLVSLTDLDLAQNLLEALPDGIAKLSRLTILKLDQNRL---------------QRLNDTLGNC-------------------------ENMQELILTENFLSELPASIGQMTKLNNLNVDRNALEYLPLEIGQCANLGVLSLRDNKLKKLPPELGNCTVLHVLDVSGNQLLYLPYSL 378
BLAST of Roc domain-containing protein vs. Ensembl Fly
Match: scrib (gene:FBgn0263289 transcript:FBtr0308622) HSP 1 Score: 74.7146 bits (182), Expect = 4.125e-13 Identity = 86/359 (23.96%), Postives = 153/359 (42.62%), Query Frame = 3
Query: 249 VPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDSNMESLLQSGQILSDHISNTIFDLPAVQAVEMEFCKINYFKSFQSKALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISLDYYNKSLETLKXXXXXXXXXXXXXXYLEKLENLDVSSNNISELPLDLCLMKNI 1325
+P F+ + L +S+N I LP DI + NL L++SRN D+ +P +K+L+ L+ + S + +P+ ++ +L L ++ ++ L +D G+L QL+ L + LK LP+ I KL+ L L N I+ +P L + L L + DH N + LP + K+ Y L +S N +E+P + L +LT L L N +E + + ++ L +L L N++++L +L ++++ L + N + +P I + KL NL+V N + LPL++ N+
Sbjct: 52 LPKNFFRLHRLRKLGLSDNEIGRLPPDIQNFENLVELDVSRN--------DIPDIPDDIKHLQSLQVADFSSNPIPKLPSGFSQLKNLTVLGLNDMSLTTLPADFGSLTQLESLELRENLLKHLPETISQLTKLKRLDLGDNEIEDLPPYLGYLPGLHELWL------------------------DH--NQLQRLPPELGL---LTKLTY-----------LDVSENRLEELPNEISGL-----------------------VSLTDLDLAQNLLEALPDGIAKLSRLTILKLDQNRLQRLNDTLGNC-ENMQELILTENFLSELPASIGQMTKLNNLNVDRNALEYLPLEIGQCANL 338 HSP 2 Score: 71.2478 bits (173), Expect = 4.721e-12 Identity = 51/178 (28.65%), Postives = 92/178 (51.69%), Query Frame = 3
Query: 225 LSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPK----------------SMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADI 710
L + L +P L ++T+L+VSEN ++ LP +IS LV+L L++++N PD + L + ++ N + ++ L ++E L +PA+I ++T L+ L++ +N + L +IG L L+ + LK LP E+ C L L + GN + +PY L ++
Sbjct: 205 LDHNQLQRLPPELGLLTKLTYLDVSENRLEELPNEISGLVSLTDLDLAQNLLEAL-PDGIAKLSRLTILKLDQNRLQRLNDTLGNCENMQELILTENFLSELPASIGQMTKLNNLNVDRNALEYLPLEIGQCANLGVLSLRDNKLKKLPPELGNCTVLHVLDVSGNQLLYLPYSLVNL 381 HSP 3 Score: 71.2478 bits (173), Expect = 5.009e-12 Identity = 77/327 (23.55%), Postives = 144/327 (44.04%), Query Frame = 3
Query: 204 DDFKSI------NLSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDSNMESLLQSGQILSDHISNTIFDLPAVQAVEMEFCKINYFKSFQSKALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISL 1166
DD K + + S+ + +P + +T L +++ ++ +LPAD L LE L + N + LP+++ L LK L++ + + +P + + LH+L + N + L ++G L +L +L+ L+ LP EI G L L L N+++ +P +A + L L ++ L Q L+D + N + + EL ++ NF E+P ++ + L L++ +N L + ++ + NL L L+ N+++K+ L L VLD+S N++ L SL
Sbjct: 100 DDIKHLQSLQVADFSSNPIPKLPSGFSQLKNLTVLGLNDMSLTTLPADFGSLTQLESLELREN--------LLKHLPETISQLTKLKRLDLGDNEIEDLPPYLGYLPGLHELWLDHNQLQRLPPELGLLTKLTYLDVSENRLEELPNEISGLVSLTDLDLAQNLLEALPDGIAKLSRLTILKLDQNRL---------------QRLNDTLGN-------------------------CENMQELILTENFLSELPASIGQMTKLNNLNVDRNALEYLPLEIGQCANLGVLSLRDNKLKKLPPELGNCTVLHVLDVSGNQLLYLPYSL 378
BLAST of Roc domain-containing protein vs. Ensembl Fly
Match: scrib (gene:FBgn0263289 transcript:FBtr0308628) HSP 1 Score: 74.7146 bits (182), Expect = 4.545e-13 Identity = 86/359 (23.96%), Postives = 153/359 (42.62%), Query Frame = 3
Query: 249 VPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDSNMESLLQSGQILSDHISNTIFDLPAVQAVEMEFCKINYFKSFQSKALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISLDYYNKSLETLKXXXXXXXXXXXXXXYLEKLENLDVSSNNISELPLDLCLMKNI 1325
+P F+ + L +S+N I LP DI + NL L++SRN D+ +P +K+L+ L+ + S + +P+ ++ +L L ++ ++ L +D G+L QL+ L + LK LP+ I KL+ L L N I+ +P L + L L + DH N + LP + K+ Y L +S N +E+P + L +LT L L N +E + + ++ L +L L N++++L +L ++++ L + N + +P I + KL NL+V N + LPL++ N+
Sbjct: 52 LPKNFFRLHRLRKLGLSDNEIGRLPPDIQNFENLVELDVSRN--------DIPDIPDDIKHLQSLQVADFSSNPIPKLPSGFSQLKNLTVLGLNDMSLTTLPADFGSLTQLESLELRENLLKHLPETISQLTKLKRLDLGDNEIEDLPPYLGYLPGLHELWL------------------------DH--NQLQRLPPELGL---LTKLTY-----------LDVSENRLEELPNEISGL-----------------------VSLTDLDLAQNLLEALPDGIAKLSRLTILKLDQNRLQRLNDTLGNC-ENMQELILTENFLSELPASIGQMTKLNNLNVDRNALEYLPLEIGQCANL 338 HSP 2 Score: 71.2478 bits (173), Expect = 5.187e-12 Identity = 51/178 (28.65%), Postives = 92/178 (51.69%), Query Frame = 3
Query: 225 LSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPK----------------SMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADI 710
L + L +P L ++T+L+VSEN ++ LP +IS LV+L L++++N PD + L + ++ N + ++ L ++E L +PA+I ++T L+ L++ +N + L +IG L L+ + LK LP E+ C L L + GN + +PY L ++
Sbjct: 205 LDHNQLQRLPPELGLLTKLTYLDVSENRLEELPNEISGLVSLTDLDLAQNLLEAL-PDGIAKLSRLTILKLDQNRLQRLNDTLGNCENMQELILTENFLSELPASIGQMTKLNNLNVDRNALEYLPLEIGQCANLGVLSLRDNKLKKLPPELGNCTVLHVLDVSGNQLLYLPYSLVNL 381 HSP 3 Score: 71.2478 bits (173), Expect = 5.550e-12 Identity = 77/327 (23.55%), Postives = 144/327 (44.04%), Query Frame = 3
Query: 204 DDFKSI------NLSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDSNMESLLQSGQILSDHISNTIFDLPAVQAVEMEFCKINYFKSFQSKALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISL 1166
DD K + + S+ + +P + +T L +++ ++ +LPAD L LE L + N + LP+++ L LK L++ + + +P + + LH+L + N + L ++G L +L +L+ L+ LP EI G L L L N+++ +P +A + L L ++ L Q L+D + N + + EL ++ NF E+P ++ + L L++ +N L + ++ + NL L L+ N+++K+ L L VLD+S N++ L SL
Sbjct: 100 DDIKHLQSLQVADFSSNPIPKLPSGFSQLKNLTVLGLNDMSLTTLPADFGSLTQLESLELREN--------LLKHLPETISQLTKLKRLDLGDNEIEDLPPYLGYLPGLHELWLDHNQLQRLPPELGLLTKLTYLDVSENRLEELPNEISGLVSLTDLDLAQNLLEALPDGIAKLSRLTILKLDQNRL---------------QRLNDTLGN-------------------------CENMQELILTENFLSELPASIGQMTKLNNLNVDRNALEYLPLEIGQCANLGVLSLRDNKLKKLPPELGNCTVLHVLDVSGNQLLYLPYSL 378
BLAST of Roc domain-containing protein vs. Ensembl Zebrafish
Match: lrrc7 (leucine rich repeat containing 7 [Source:ZFIN;Acc:ZDB-GENE-130530-876]) HSP 1 Score: 83.9593 bits (206), Expect = 8.112e-16 Identity = 92/367 (25.07%), Postives = 150/367 (40.87%), Query Frame = 3
Query: 249 VPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFH----------CTS------------PDDMT----------------ILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGEL------------------RSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDSNMESLLQSGQILS-----DHISNTIFDLPAVQAVEMEFCKINYFKSFQSKALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISL 1166
+P LF + L++ +N++ +LP I+ LVNL+ L+IS+NG C S P+ T LP + L L+ L + E +L +P +I ++ L +LD+ N EL R IG L QL++L+ +++L +I GCE LE LLL N++Q +P + + L TL ++ D+ + SL + LS D N + LP I Y S ++ A E NF ++P + N N+T + L+ N++E + + QM L+VL+LS N++K L +
Sbjct: 61 LPKQLFNCQALKKLSMPDNDLSNLPTTIASLVNLKELDISKNGIQEFPDNIKCCKCLSVVEASVNPIAKLPEGFTQLLNLTQLFLNDAFLEYLPANFGRLSKLRILELRENHLKTMPKSIHRLSQLERLDLGSNEFSELVRKMLSSVSALSMDFGFSRESIGKLRQLRYLDLAKNRIESLDADISGCESLEDLLLSANMLQQLPDSIGKLKKLTTLKVD--------DNQLTSLPNTIGSLSLLEEFDCSCNELESLPPT---------IGYLHSLRTFAADE-----NFLSDLPREIGNCR-----------------------NVTVMSLRSNKLEFLPDEIGQMTKLRVLNLSDNRLKNLPFTF 382
BLAST of Roc domain-containing protein vs. Ensembl Zebrafish
Match: erbin (erbb2 interacting protein [Source:ZFIN;Acc:ZDB-GENE-061103-403]) HSP 1 Score: 78.9518 bits (193), Expect = 1.445e-14 Identity = 74/290 (25.52%), Postives = 128/290 (44.14%), Query Frame = 3
Query: 318 LPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDSNMESLLQSGQILSDHISNTIFDLPAVQAVEMEFCKINYFKS--FQSKALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISLDYYNK 1181
LPA L L++L + N + +LPKSM L L+ L++ +P + ++T + +L + N + + IG L QL +L+ ++ + ++I GCE L+ LLL N + +P IGSLK LS K+D N Q++ ++ +TI L + ++ F +I S Q L N ++P + +L N+T L+L N++E + + + M+ LKV++LS NK++ L S N+
Sbjct: 137 LPASFGRLTKLQILELREN--------QLKMLPKSMHKLTQLERLDLGSNEFTEVPEVLEQLTGIRELWMDGNKLTFVPGMIGALKQLSYLDVSKNNVEMVEEQISGCENLQDLLLSNNALTQLP---GSIGSLKKLST------LKVDDN--------QLM--YLPDTIGGLSHLDELDCSFNEIEALPSSIGQCVNLRTFAADHNLLAQMPPEMGSLK-----------------------NVTVLFLHSNKLENLPEEMGDMQKLKVINLSDNKLRNLPYSFTKLNQ 376 HSP 2 Score: 77.0258 bits (188), Expect = 5.469e-14 Identity = 54/178 (30.34%), Postives = 94/178 (52.81%), Query Frame = 3
Query: 225 LSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSIN---LRHL 749
+ LT VP + ++++L+VS+NN++ + IS NL+ L +S N +T LP S+ +LK L L + + L+++P TI ++ L +LD S N I L S IG L+ A H L +P E+ + + L L+ N ++ +P + D+ LK ++++ LR+L
Sbjct: 198 MDGNKLTFVPGMIGALKQLSYLDVSKNNVEMVEEQISGCENLQDLLLSNNA--------LTQLPGSIGSLKKLSTLKVDDNQLMYLPDTIGGLSHLDELDCSFNEIEALPSSIGQCVNLRTFAADHNLLAQMPPEMGSLKNVTVLFLHSNKLENLPEEMGDMQKLKVINLSDNKLRNL 367
BLAST of Roc domain-containing protein vs. Ensembl Zebrafish
Match: erbin (erbb2 interacting protein [Source:ZFIN;Acc:ZDB-GENE-061103-403]) HSP 1 Score: 78.9518 bits (193), Expect = 1.445e-14 Identity = 74/290 (25.52%), Postives = 128/290 (44.14%), Query Frame = 3
Query: 318 LPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDSNMESLLQSGQILSDHISNTIFDLPAVQAVEMEFCKINYFKS--FQSKALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISLDYYNK 1181
LPA L L++L + N + +LPKSM L L+ L++ +P + ++T + +L + N + + IG L QL +L+ ++ + ++I GCE L+ LLL N + +P IGSLK LS K+D N Q++ ++ +TI L + ++ F +I S Q L N ++P + +L N+T L+L N++E + + + M+ LKV++LS NK++ L S N+
Sbjct: 137 LPASFGRLTKLQILELREN--------QLKMLPKSMHKLTQLERLDLGSNEFTEVPEVLEQLTGIRELWMDGNKLTFVPGMIGALKQLSYLDVSKNNVEMVEEQISGCENLQDLLLSNNALTQLP---GSIGSLKKLST------LKVDDN--------QLM--YLPDTIGGLSHLDELDCSFNEIEALPSSIGQCVNLRTFAADHNLLAQMPPEMGSLK-----------------------NVTVLFLHSNKLENLPEEMGDMQKLKVINLSDNKLRNLPYSFTKLNQ 376 HSP 2 Score: 77.0258 bits (188), Expect = 5.469e-14 Identity = 54/178 (30.34%), Postives = 94/178 (52.81%), Query Frame = 3
Query: 225 LSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSIN---LRHL 749
+ LT VP + ++++L+VS+NN++ + IS NL+ L +S N +T LP S+ +LK L L + + L+++P TI ++ L +LD S N I L S IG L+ A H L +P E+ + + L L+ N ++ +P + D+ LK ++++ LR+L
Sbjct: 198 MDGNKLTFVPGMIGALKQLSYLDVSKNNVEMVEEQISGCENLQDLLLSNNA--------LTQLPGSIGSLKKLSTLKVDDNQLMYLPDTIGGLSHLDELDCSFNEIEALPSSIGQCVNLRTFAADHNLLAQMPPEMGSLKNVTVLFLHSNKLENLPEEMGDMQKLKVINLSDNKLRNL 367
BLAST of Roc domain-containing protein vs. Ensembl Zebrafish
Match: erbin (erbb2 interacting protein [Source:ZFIN;Acc:ZDB-GENE-061103-403]) HSP 1 Score: 78.9518 bits (193), Expect = 1.519e-14 Identity = 74/290 (25.52%), Postives = 128/290 (44.14%), Query Frame = 3
Query: 318 LPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDSNMESLLQSGQILSDHISNTIFDLPAVQAVEMEFCKINYFKS--FQSKALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISLDYYNK 1181
LPA L L++L + N + +LPKSM L L+ L++ +P + ++T + +L + N + + IG L QL +L+ ++ + ++I GCE L+ LLL N + +P IGSLK LS K+D N Q++ ++ +TI L + ++ F +I S Q L N ++P + +L N+ T L+L N++E + + + M+ LKV++LS NK++ L S N+
Sbjct: 153 LPASFGRLTKLQILELREN--------QLKMLPKSMHKLTQLERLDLGSNEFTEVPEVLEQLTGIRELWMDGNKLTFVPGMIGALKQLSYLDVSKNNVEMVEEQISGCENLQDLLLSNNALTQLP---GSIGSLKKLST------LKVDDN--------QLM--YLPDTIGGLSHLDELDCSFNEIEALPSSIGQCVNLRTFAADHNLLAQMPPEMGSLKNV-----------------------TVLFLHSNKLENLPEEMGDMQKLKVINLSDNKLRNLPYSFTKLNQ 392 HSP 2 Score: 77.0258 bits (188), Expect = 5.592e-14 Identity = 54/178 (30.34%), Postives = 94/178 (52.81%), Query Frame = 3
Query: 225 LSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSIN---LRHL 749
+ LT VP + ++++L+VS+NN++ + IS NL+ L +S N +T LP S+ +LK L L + + L+++P TI ++ L +LD S N I L S IG L+ A H L +P E+ + + L L+ N ++ +P + D+ LK ++++ LR+L
Sbjct: 214 MDGNKLTFVPGMIGALKQLSYLDVSKNNVEMVEEQISGCENLQDLLLSNNA--------LTQLPGSIGSLKKLSTLKVDDNQLMYLPDTIGGLSHLDELDCSFNEIEALPSSIGQCVNLRTFAADHNLLAQMPPEMGSLKNVTVLFLHSNKLENLPEEMGDMQKLKVINLSDNKLRNL 383
BLAST of Roc domain-containing protein vs. Ensembl Zebrafish
Match: lrrc7 (leucine rich repeat containing 7 [Source:ZFIN;Acc:ZDB-GENE-130530-876]) HSP 1 Score: 78.5666 bits (192), Expect = 3.324e-14 Identity = 91/372 (24.46%), Postives = 149/372 (40.05%), Query Frame = 3
Query: 249 VPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFH----------CTS------------PDDMT----------------ILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGEL-----------------------RSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDSNMESLLQSGQILS-----DHISNTIFDLPAVQAVEMEFCKINYFKSFQSKALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISL 1166
+P LF + L++ +N++ +LP I+ LVNL+ L+IS+NG C S P+ T LP + L L+ L + E +L +P +I ++ L +LD+ N EL IG L QL++L+ +++L +I GCE LE LLL N++Q +P + + L TL ++ D+ + SL + LS D N + LP I Y S ++ A E NF ++P + N N+T + L+ N++E + + QM L+VL+LS N++K L +
Sbjct: 61 LPKQLFNCQALKKLSMPDNDLSNLPTTIASLVNLKELDISKNGIQEFPDNIKCCKCLSVVEASVNPIAKLPEGFTQLLNLTQLFLNDAFLEYLPANFGRLSKLRILELRENHLKTMPKSIHRLSQLERLDLGSNEFSELPEVLEQIHSLKELWLDNNSLQTIPGSIGKLRQLRYLDLAKNRIESLDADISGCESLEDLLLSANMLQQLPDSIGKLKKLTTLKVD--------DNQLTSLPNTIGSLSLLEEFDCSCNELESLPPT---------IGYLHSLRTFAADE-----NFLSDLPREIGNCR-----------------------NVTVMSLRSNKLEFLPDEIGQMTKLRVLNLSDNRLKNLPFTF 387 HSP 2 Score: 57.7658 bits (138), Expect = 6.935e-8 Identity = 52/189 (27.51%), Postives = 89/189 (47.09%), Query Frame = 3
Query: 210 FKSINLSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPD----------------DMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTL 728
K + L N +L +P ++ K ++ +L++++N I+SL ADIS +LE L +S N PD +T LP ++ +L L+ + S L +P TI + SL +N + +L +IGN + ++ + L+ LP EI KL L L N ++ +P+ + L L
Sbjct: 209 LKELWLDNNSLQTIPGSIGKLRQLRYLDLAKNRIESLDADISGCESLEDLLLSANMLQQL-PDSIGKLKKLTTLKVDDNQLTSLPNTIGSLSLLEEFDCSCNELESLPPTIGYLHSLRTFAADENFLSDLPREIGNCRNVTVMSLRSNKLEFLPDEIGQMTKLRVLNLSDNRLKNLPFTFTKLKDLAAL 396 HSP 3 Score: 56.225 bits (134), Expect = 2.533e-7 Identity = 108/412 (26.21%), Postives = 181/412 (43.93%), Query Frame = 3
Query: 246 VVPVTLFKRIE--ITHLNVSENNIKSLPADI-SDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDSNMESLLQSGQILSDHISNTIFDLPAVQAVEMEFCKINYFKSFQSKALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISLDYYNKSLETLKXXXXXXXXXXXXXXYLEKLENLDVSSNNISELPLDLCLMKNIKT----AHYFNGLHR-IG-------LWVSSNPIEFPPKCVWNTTNIDVI 1436
+VP F+ E I+ L+ S +++ +P +I S LE L + N + LPK + N + LK L++ + +L +P TI + +L +LDISKN I E +I L + A + LP+ L L L ++ +P + L+ L + HL + + ++ L Q ++ D SN +LP V +E Q +L EL + N Q IP ++ L L+ L L N+IE + + +SL+ L LS N +++L S+ K L TLK++ N + ++PN I L LE D S N + LP + + +++T ++ + L R IG + + SN +EF P + T + V+
Sbjct: 11 LVPCRCFRGEEEVISVLDYSHCSLQQVPKEIFSFERTLEELYLDAN--------QIEELPKQLFNCQALKKLSMPDNDLSNLPTTIASLVNLKELDISKNGIQEFPDNIKCCKCLSVVEASVNPIAKLPEGFTQLLNLTQLFLNDAFLEYLPANFGRLSKLRILELRENHL-KTMPKSIHRLSQLERL--DLGSNEFSELPEV----LE----------QIHSLKELWLDNNSLQTIPGSIGKLRQLRY-----------------------LDLAKNRIESLDADISGCESLEDLLLSANMLQQLPDSIGKLKK-LTTLKVDDNQLTSLPNTIGSLSLLEEFDCSCNELESLPPTIGYLHSLRTFAADENFLSDLPREIGNCRNVTVMSLRSNKLEFLPDEIGQMTKLRVL 373
BLAST of Roc domain-containing protein vs. Ensembl Xenopus
Match: LRRD1 (leucine-rich repeats and death domain containing 1 [Source:NCBI gene;Acc:100490254]) HSP 1 Score: 85.8853 bits (211), Expect = 1.747e-16 Identity = 105/388 (27.06%), Postives = 188/388 (48.45%), Query Frame = 3
Query: 225 LSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSI-------------NLRHLGE---------KIDSNMESLLQ------SGQILSDHISNTIFDLPAVQAVEMEFCKINYF--KSFQSKALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISLDYYNKSLETLKXXXXXXXXXXXXXXYLEKLENLDVSSNNISELP 1298
LSN +T +P +L ++ L++ N + SLP +I L L LN++ N + +LP + LK +K L + L +P + ++T+L L IS N++ L +L L LN + LP+ + +L L L GN I+++P + D+ +L+ LS+ NL L E I +++L Q + +L+D I+ + PA++ +++ ++ K + L ELHI N + +P+ + +LNNL ++ + N LL I +L +T L L GN++ ++ ++L M SL L+L+ N+I ++ S+ +N+ LE L+++ N + L L LD+S N I+ +P
Sbjct: 69 LSNNFMTHLPTSLCHLSKLEILSLEGNALVSLPPEICSLSQLTALNVNHN--------QIAVLPHEISGLKNIKQLFANNNKLSQLPPCLGDLTTLQVLCISGNSMKTLPDSTASLKNLHVLNLDGNQISALPKAVFRLSQLVKLCLSGNQIKSLPKEIGDLKNLRELSLSSNQLTFLPVQLYNLTSLEELTLDDNKLTAISDKLQNLKQLKVLSIANNLLTD-ITEKVCWCPAIECLKLNGNQMYRLPTKIHNLRNLKELHIERNALEMLPDQLAHLNNLSVIVCANNNLLWIPIELKNCNQITKLDLSGNKLSEVPQALSSMTSLLYLNLNQNEIHEIANSI-IHNRKLEHLELSGNKLTVFSVHFCGLHNLAYLDLSRNEINSVP 446 HSP 2 Score: 81.6481 bits (200), Expect = 4.169e-15 Identity = 117/434 (26.96%), Postives = 200/434 (46.08%), Query Frame = 3
Query: 219 INLSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNG--------FHCTSPDDMTI-------LPKSMKNLKCLKYLNIS-----------------EC------NLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDS-----NMESLLQSGQILSDHISNTIFDLPAVQAVEMEFCKINYFKSFQSKALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISLDYYNKSLETLKXXXXXXXXXXXXXXYLEKLENL---DVSSNNISELPLDLCLMKN-IKTAHYFNGLHRIGLWVSS 1379
+NL ++ +P +F+ ++ L +S N IKSLP +I DL NL L++S N ++ TS +++T+ + ++NLK LK L+I+ EC + +P I + +L +L I +N + L + +L+ L + + L +P E+ C ++ L L GN + +P L+ + SL L++N + E +S +E L SG L T+F + FC ++ L L +S N +P + NL +L L L N +L L++L + L GNQIE + + ++ L+ ++LS+N K L + SLETLKI+ + + + + L KL+NL ++S NNI LP + MKN ++ N L+ + +SS
Sbjct: 182 LNLDGNQISALPKAVFRLSQLVKLCLSGNQIKSLPKEIGDLKNLRELSLSSNQLTFLPVQLYNLTSLEELTLDDNKLTAISDKLQNLKQLKVLSIANNLLTDITEKVCWCPAIECLKLNGNQMYRLPTKIHNLRNLKELHIERNALEMLPDQLAHLNNLSVIVCANNNLLWIPIELKNCNQITKLDLSGNKLSEVPQALSSMTSLLYLNLNQNEIHEIANSIIHNRKLEHLELSGNKL------TVFS--------VHFCGLHN--------LAYLDLSRNEINSVPSAISNLESLSELLLHSNKFRRFPIELCALKSLQKIDLSGNQIETVPSGISLLEGLRYVNLSNNSFKVFPREL-FSVSSLETLKISQKDGRKLISLPDELSKLKNLKELEISDNNIKTLPGSIGEMKNLVQLTATSNQLYHLPASISS 592 HSP 3 Score: 75.8702 bits (185), Expect = 2.180e-13 Identity = 99/395 (25.06%), Postives = 192/395 (48.61%), Query Frame = 3
Query: 207 DFKSINLSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFH---------------CTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDSNMESLLQSGQILSDHISNTIFDLPAVQAVEMEFCKINYFKSFQSKALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISLDYYNKSLETLKXXXXXXXXXXXXXXYLEKLENLDVSSNNISELPLDLCLMKNIKTAHYFN 1346
+ K + +N L+ +P L + L +S N++K+LP + L NL VLN+ N C S + + LPK + +LK L+ L++S L F+P ++ +TSL +L + N + + + NL QL+ L+ + L + +++ C +E L L GN + +P + ++ +LK L I R+ E + + L I+ + N + +P +E++ C + +L +SGN E+P+ + ++ +L L+L++N + I + +I L L L GN++ + + +L LDLS N+I + ++ +SL L ++ N + P ++ L+ L+ +D+S N I +P + L++ ++ + N
Sbjct: 132 NIKQLFANNNKLSQLPPCLGDLTTLQVLCISGNSMKTLPDSTASLKNLHVLNLDGNQISALPKAVFRLSQLVKLCLSGNQIKSLPKEIGDLKNLRELSLSSNQLTFLPVQLYNLTSLEELTLDDNKLTAISDKLQNLKQLKVLSIANNLLTDITEKVCWCPAIECLKLNGNQMYRLPTKIHNLRNLKELHIE-RNALEMLPDQLAHLNNLSVIVCAN--NNLLWIP----IELKNC----------NQITKLDLSGNKLSEVPQALSSMTSLLYLNLNQNEIHEIANSIIHNRKLEHLELSGNKLTVFSVHFCGLHNLAYLDLSRNEINSVPSAISNL-ESLSELLLHSNKFRRFPIELCALKSLQKIDLSGNQIETVPSGISLLEGLRYVNLSN 508 HSP 4 Score: 65.4698 bits (158), Expect = 4.434e-10 Identity = 52/170 (30.59%), Postives = 84/170 (49.41%), Query Frame = 3
Query: 252 PVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFH--------CTSPDDMTI----------LPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLAD 707
P+ L + +++S N I+++P+ IS L L +N+S N F +S + + I LP + LK LK L IS+ N+ +P +I E+ +L QL + N + L + I +L LQ L+ + L +LP +I G +KL + L N + P LL D
Sbjct: 469 PIELCALKSLQKIDLSGNQIETVPSGISLLEGLRYVNLSNNSFKVFPRELFSVSSLETLKISQKDGRKLISLPDELSKLKNLKELEISDNNIKTLPGSIGEMKNLVQLTATSNQLYHLPASISSLAALQQLSLKGNQLTSLPSDISGLQKLREINLDSNPMLRPPSLLCD 638 HSP 5 Score: 62.7734 bits (151), Expect = 2.488e-9 Identity = 89/359 (24.79%), Postives = 177/359 (49.30%), Query Frame = 3
Query: 279 ITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDSNMESLLQSGQILSDHISNT--------IFDLPAVQAVEMEFCKINYF--KSFQSKALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISLDYYNKSLETLKXXXXXXXXXXXXXXYLEKLENLDVSSNNISELPLDLCLMKNI 1325
IT +N++ + +P D+ NL+ L +S N MT LP S+ +L L+ L++ LV +P I ++ L L+++ N I L +I L ++ L A + L LP + L+ L + GN ++T+P A + +L L+++ G +I + +++ + Q++ +S I DL ++ + + ++ + + + +L EL + N I + + NL L++L ++ NLL +I + + + L L GNQ+ ++ + +++LK L + N ++ L L + N +L + +NN+ IP ++ ++ LD+S N +SE+P L M ++
Sbjct: 41 ITSINLNSKELTEIPPDVFRCTNLQCLLLSNNF--------MTHLPTSLCHLSKLEILSLEGNALVSLPPEICSLSQLTALNVNHNQIAVLPHEISGLKNIKQLFANNNKLSQLPPCLGDLTTLQVLCISGNSMKTLPDSTASLKNLHVLNLD----GNQISALPKAVFRLSQLVKLCLSGNQIKSLPKEIGDLKNLRELSLSSNQLTFLPVQLYNLTSLEELTLDDNKLTAISDKLQNLKQLKVLSIANNLLTDITEKVCWCPAIECLKLNGNQMYRLPTKIHNLRNLKELHIERNALEMLPDQLAHLN-NLSVIVCANNNLLWIPIELKNCNQITKLDLSGNKLSEVPQALSSMTSL 386 HSP 6 Score: 58.9214 bits (141), Expect = 4.452e-8 Identity = 42/133 (31.58%), Postives = 68/133 (51.13%), Query Frame = 3
Query: 204 DDFKSINLSNTALTVVPVTLFKRIEITHLNVSENNIK---SLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLN 593
+ + +NLSN + V P LF + L +S+ + + SLP ++S L NL+ L IS N ++ LP S+ +K L L + L +PA+I + +L QL + N + L SDI L +L+ +N
Sbjct: 499 EGLRYVNLSNNSFKVFPRELFSVSSLETLKISQKDGRKLISLPDELSKLKNLKELEISDN--------NIKTLPGSIGEMKNLVQLTATSNQLYHLPASISSLAALQQLSLKGNQLTSLPSDISGLQKLREIN 623
BLAST of Roc domain-containing protein vs. Ensembl Xenopus
Match: prrc2a (proline rich coiled-coil 2A [Source:Xenbase;Acc:XB-GENE-482976]) HSP 1 Score: 82.4185 bits (202), Expect = 3.265e-15 Identity = 84/343 (24.49%), Postives = 150/343 (43.73%), Query Frame = 3
Query: 249 VPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFH--------C-------TSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSD-----------------IGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDSNMESLLQSGQILSDHISNTIFDLPAVQAVEMEFCKINYFKS-----FQSKALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISL 1166
+P LF + L++ +N++ LPA I++L+NL L++S+NG C S + ++ LP L L L +++ L F+PA +T L L++ +N + L + +GNL QL +L+ ++ + I GCE L+ LLL N IQ +P IG+LK L+ K+D N Q++ ++ ++I L A++ ++ F +I S Q + H NF ++P + ++ T L+L N++E + + + M+ LKV++LS N+++ L S
Sbjct: 61 LPKQLFNCQSLHKLSLPDNDLTILPASIANLINLRELDVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLDFLPANFGRLTKLQILELRENQLKMLPNGLKEFWMDGNKLTYIPGFLGNLKQLTYLDVSKNNIEMVEDGISGCESLQDLLLSSNAIQQLP---ESIGALKKLTT------LKVDEN--------QLM--YLPDSIGGLTAIEDLDCSFNEIEALPSSIGHLIQIRTFAADH---NFLTQLPPEI-----------------------GTWKSATVLFLHSNKLESLPEEMGDMQKLKVINLSDNRLRNLPFSF 358 HSP 2 Score: 78.5666 bits (192), Expect = 5.426e-14 Identity = 57/178 (32.02%), Postives = 95/178 (53.37%), Query Frame = 3
Query: 225 LSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSIN---LRHL 749
+ LT +P L ++T+L+VS+NNI+ + IS +L+ L +S N LP+S+ LK L L + E L+++P +I +T++ LD S N I L S IG+L Q++ A H L LP EI + L L+ N ++++P + D+ LK ++++ LR+L
Sbjct: 185 MDGNKLTYIPGFLGNLKQLTYLDVSKNNIEMVEDGISGCESLQDLLLSSNAIQQ--------LPESIGALKKLTTLKVDENQLMYLPDSIGGLTAIEDLDCSFNEIEALPSSIGHLIQIRTFAADHNFLTQLPPEIGTWKSATVLFLHSNKLESLPEEMGDMQKLKVINLSDNRLRNL 354
BLAST of Roc domain-containing protein vs. Ensembl Xenopus
Match: prrc2a (proline rich coiled-coil 2A [Source:Xenbase;Acc:XB-GENE-482976]) HSP 1 Score: 80.1073 bits (196), Expect = 1.827e-14 Identity = 73/321 (22.74%), Postives = 143/321 (44.55%), Query Frame = 3
Query: 219 INLSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDSNMESLLQSGQILSDHISNTIFDLPAVQAVEMEFCKINYFKS-----FQSKALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISL 1166
+ S ++ +P + + +T L +++ + LPA+ L L++L + N + +LPK+M L L+ L++ +P + +++ L + + N + + +GNL QL +L+ ++ + I GCE L+ LLL N IQ +P IG+LK L+ K+D N Q++ ++ ++I L A++ ++ F +I S Q + H NF ++P + ++ T L+L N++E + + + M+ LKV++LS N+++ L S
Sbjct: 157 VEASVNPISKLPDGFSQLLNLTQLYLNDAFLDFLPANFGRLTKLQILELREN--------QLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDGNKLTYIPGFLGNLKQLTYLDVSKNNIEMVEDGISGCESLQDLLLSSNAIQQLP---ESIGALKKLTT------LKVDEN--------QLM--YLPDSIGGLTAIEDLDCSFNEIEALPSSIGHLIQIRTFAADH---NFLTQLPPEI-----------------------GTWKSATVLFLHSNKLESLPEEMGDMQKLKVINLSDNRLRNLPFSF 424 HSP 2 Score: 56.225 bits (134), Expect = 3.627e-7 Identity = 90/328 (27.44%), Postives = 139/328 (42.38%), Query Frame = 3
Query: 411 LPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDSNMESLLQSGQILSDHISNTIFDLPAVQAVEMEFCKINYFKSFQSKALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISLDYYNKSLETLKXXXXXXXXXXXXXXYLEKLENLDVSSNNISELPLDLCLMKNIKT-AHYFNGLHR----IGLWVSS 1379
LPK + N + L L++ + +L +PA+I + +L +LD+SKN I E +I N L + A + LP L L L + +P + L+ L + L + + M L Q ++ D SN ++P V +E Q L E + GN IP + NL LT L + N IE + + +SL+ L LS N I++L S+ K L TLK++ N + +P+ I L +E+LD S N I LP + + I+T A N L + IG W S+
Sbjct: 98 LPKQLFNCQSLHKLSLPDNDLTILPASIANLINLRELDVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLDFLPANFGRLTKLQILELRENQL-KMLPKTMNRLTQLERL--DLGSNEFTEVPEV----LE----------QLSGLKEFWMDGNKLTYIPGFLGNLK-----------------------QLTYLDVSKNNIEMVEDGISGCESLQDLLLSSNAIQQLPESIGAL-KKLTTLKVDENQLMYLPDSIGGLTAIEDLDCSFNEIEALPSSIGHLIQIRTFAADHNFLTQLPPEIGTWKSA 384
BLAST of Roc domain-containing protein vs. Ensembl Xenopus
Match: prrc2a (proline rich coiled-coil 2A [Source:Xenbase;Acc:XB-GENE-482976]) HSP 1 Score: 79.7221 bits (195), Expect = 2.087e-14 Identity = 73/321 (22.74%), Postives = 143/321 (44.55%), Query Frame = 3
Query: 219 INLSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDSNMESLLQSGQILSDHISNTIFDLPAVQAVEMEFCKINYFKS-----FQSKALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISL 1166
+ S ++ +P + + +T L +++ + LPA+ L L++L + N + +LPK+M L L+ L++ +P + +++ L + + N + + +GNL QL +L+ ++ + I GCE L+ LLL N IQ +P IG+LK L+ K+D N Q++ ++ ++I L A++ ++ F +I S Q + H NF ++P + ++ T L+L N++E + + + M+ LKV++LS N+++ L S
Sbjct: 157 VEASVNPISKLPDGFSQLLNLTQLYLNDAFLDFLPANFGRLTKLQILELREN--------QLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDGNKLTYIPGFLGNLKQLTYLDVSKNNIEMVEDGISGCESLQDLLLSSNAIQQLP---ESIGALKKLTT------LKVDEN--------QLM--YLPDSIGGLTAIEDLDCSFNEIEALPSSIGHLIQIRTFAADH---NFLTQLPPEI-----------------------GTWKSATVLFLHSNKLESLPEEMGDMQKLKVINLSDNRLRNLPFSF 424 HSP 2 Score: 55.8398 bits (133), Expect = 3.843e-7 Identity = 90/328 (27.44%), Postives = 139/328 (42.38%), Query Frame = 3
Query: 411 LPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDSNMESLLQSGQILSDHISNTIFDLPAVQAVEMEFCKINYFKSFQSKALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISLDYYNKSLETLKXXXXXXXXXXXXXXYLEKLENLDVSSNNISELPLDLCLMKNIKT-AHYFNGLHR----IGLWVSS 1379
LPK + N + L L++ + +L +PA+I + +L +LD+SKN I E +I N L + A + LP L L L + +P + L+ L + L + + M L Q ++ D SN ++P V +E Q L E + GN IP + NL LT L + N IE + + +SL+ L LS N I++L S+ K L TLK++ N + +P+ I L +E+LD S N I LP + + I+T A N L + IG W S+
Sbjct: 98 LPKQLFNCQSLHKLSLPDNDLTILPASIANLINLRELDVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLDFLPANFGRLTKLQILELRENQL-KMLPKTMNRLTQLERL--DLGSNEFTEVPEV----LE----------QLSGLKEFWMDGNKLTYIPGFLGNLK-----------------------QLTYLDVSKNNIEMVEDGISGCESLQDLLLSSNAIQQLPESIGAL-KKLTTLKVDENQLMYLPDSIGGLTAIEDLDCSFNEIEALPSSIGHLIQIRTFAADHNFLTQLPPEIGTWKSA 384
BLAST of Roc domain-containing protein vs. Ensembl Xenopus
Match: prrc2a (proline rich coiled-coil 2A [Source:Xenbase;Acc:XB-GENE-482976]) HSP 1 Score: 79.7221 bits (195), Expect = 2.192e-14 Identity = 73/321 (22.74%), Postives = 143/321 (44.55%), Query Frame = 3
Query: 219 INLSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDSNMESLLQSGQILSDHISNTIFDLPAVQAVEMEFCKINYFKS-----FQSKALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISL 1166
+ S ++ +P + + +T L +++ + LPA+ L L++L + N + +LPK+M L L+ L++ +P + +++ L + + N + + +GNL QL +L+ ++ + I GCE L+ LLL N IQ +P IG+LK L+ K+D N Q++ ++ ++I L A++ ++ F +I S Q + H NF ++P + ++ T L+L N++E + + + M+ LKV++LS N+++ L S
Sbjct: 157 VEASVNPISKLPDGFSQLLNLTQLYLNDAFLDFLPANFGRLTKLQILELREN--------QLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDGNKLTYIPGFLGNLKQLTYLDVSKNNIEMVEDGISGCESLQDLLLSSNAIQQLP---ESIGALKKLTT------LKVDEN--------QLM--YLPDSIGGLTAIEDLDCSFNEIEALPSSIGHLIQIRTFAADH---NFLTQLPPEI-----------------------GTWKSATVLFLHSNKLESLPEEMGDMQKLKVINLSDNRLRNLPFSF 424 HSP 2 Score: 55.8398 bits (133), Expect = 4.272e-7 Identity = 90/328 (27.44%), Postives = 139/328 (42.38%), Query Frame = 3
Query: 411 LPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDSNMESLLQSGQILSDHISNTIFDLPAVQAVEMEFCKINYFKSFQSKALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISLDYYNKSLETLKXXXXXXXXXXXXXXYLEKLENLDVSSNNISELPLDLCLMKNIKT-AHYFNGLHR----IGLWVSS 1379
LPK + N + L L++ + +L +PA+I + +L +LD+SKN I E +I N L + A + LP L L L + +P + L+ L + L + + M L Q ++ D SN ++P V +E Q L E + GN IP + NL LT L + N IE + + +SL+ L LS N I++L S+ K L TLK++ N + +P+ I L +E+LD S N I LP + + I+T A N L + IG W S+
Sbjct: 98 LPKQLFNCQSLHKLSLPDNDLTILPASIANLINLRELDVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLDFLPANFGRLTKLQILELRENQL-KMLPKTMNRLTQLERL--DLGSNEFTEVPEV----LE----------QLSGLKEFWMDGNKLTYIPGFLGNLK-----------------------QLTYLDVSKNNIEMVEDGISGCESLQDLLLSSNAIQQLPESIGAL-KKLTTLKVDENQLMYLPDSIGGLTAIEDLDCSFNEIEALPSSIGHLIQIRTFAADHNFLTQLPPEIGTWKSA 384
BLAST of Roc domain-containing protein vs. Ensembl Mouse
Match: Lrrc7 (leucine rich repeat containing 7 [Source:MGI Symbol;Acc:MGI:2676665]) HSP 1 Score: 80.4925 bits (197), Expect = 8.822e-15 Identity = 81/321 (25.23%), Postives = 143/321 (44.55%), Query Frame = 3
Query: 219 INLSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDSNMESLLQSGQILSDHISNTIFDLPAVQAVEMEFCKINYFKSFQS-----KALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISL 1166
I S ++ +P + + +T L +++ ++ LPA+ LV L +L + N + LPKSM L L+ L++ +P + +I +L +L + N + L IG L L +L+ ++T+ +I GCE LE LLL N++Q +P + + L TL K+D N ++L NTI +L ++ + C N +S +L L + NF E+P + + N+T + L+ N++E + + + QM+ L+VL+LS N++K L S
Sbjct: 125 IEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELREN--------HLKTLPKSMHKLAQLERLDLGNNEFSELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTL---------KVDDNQLTML----------PNTIGNLSLLEEFD---CSCNELESLPPTIGYLHSLRTLAVDENFLPELPREIGSCK-----------------------NVTVMSLRSNKLEFLPEEIGQMQRLRVLNLSDNRLKNLPFSF 392
BLAST of Roc domain-containing protein vs. Ensembl Mouse
Match: Lrrc7 (leucine rich repeat containing 7 [Source:MGI Symbol;Acc:MGI:2676665]) HSP 1 Score: 80.4925 bits (197), Expect = 8.865e-15 Identity = 81/321 (25.23%), Postives = 143/321 (44.55%), Query Frame = 3
Query: 219 INLSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDSNMESLLQSGQILSDHISNTIFDLPAVQAVEMEFCKINYFKSFQS-----KALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISL 1166
I S ++ +P + + +T L +++ ++ LPA+ LV L +L + N + LPKSM L L+ L++ +P + +I +L +L + N + L IG L L +L+ ++T+ +I GCE LE LLL N++Q +P + + L TL K+D N ++L NTI +L ++ + C N +S +L L + NF E+P + + N+T + L+ N++E + + + QM+ L+VL+LS N++K L S
Sbjct: 125 IEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELREN--------HLKTLPKSMHKLAQLERLDLGNNEFSELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTL---------KVDDNQLTML----------PNTIGNLSLLEEFD---CSCNELESLPPTIGYLHSLRTLAVDENFLPELPREIGSCK-----------------------NVTVMSLRSNKLEFLPEEIGQMQRLRVLNLSDNRLKNLPFSF 392
BLAST of Roc domain-containing protein vs. Ensembl Mouse
Match: Lrrc7 (leucine rich repeat containing 7 [Source:MGI Symbol;Acc:MGI:2676665]) HSP 1 Score: 80.4925 bits (197), Expect = 8.880e-15 Identity = 81/321 (25.23%), Postives = 143/321 (44.55%), Query Frame = 3
Query: 219 INLSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDSNMESLLQSGQILSDHISNTIFDLPAVQAVEMEFCKINYFKSFQS-----KALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISL 1166
I S ++ +P + + +T L +++ ++ LPA+ LV L +L + N + LPKSM L L+ L++ +P + +I +L +L + N + L IG L L +L+ ++T+ +I GCE LE LLL N++Q +P + + L TL K+D N ++L NTI +L ++ + C N +S +L L + NF E+P + + N+T + L+ N++E + + + QM+ L+VL+LS N++K L S
Sbjct: 114 IEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELREN--------HLKTLPKSMHKLAQLERLDLGNNEFSELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTL---------KVDDNQLTML----------PNTIGNLSLLEEFD---CSCNELESLPPTIGYLHSLRTLAVDENFLPELPREIGSCK-----------------------NVTVMSLRSNKLEFLPEEIGQMQRLRVLNLSDNRLKNLPFSF 381
BLAST of Roc domain-containing protein vs. Ensembl Mouse
Match: Lrrc7 (leucine rich repeat containing 7 [Source:MGI Symbol;Acc:MGI:2676665]) HSP 1 Score: 80.4925 bits (197), Expect = 9.267e-15 Identity = 81/321 (25.23%), Postives = 143/321 (44.55%), Query Frame = 3
Query: 219 INLSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDSNMESLLQSGQILSDHISNTIFDLPAVQAVEMEFCKINYFKSFQS-----KALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISL 1166
I S ++ +P + + +T L +++ ++ LPA+ LV L +L + N + LPKSM L L+ L++ +P + +I +L +L + N + L IG L L +L+ ++T+ +I GCE LE LLL N++Q +P + + L TL K+D N ++L NTI +L ++ + C N +S +L L + NF E+P + + N+T + L+ N++E + + + QM+ L+VL+LS N++K L S
Sbjct: 158 IEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELREN--------HLKTLPKSMHKLAQLERLDLGNNEFSELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTL---------KVDDNQLTML----------PNTIGNLSLLEEFD---CSCNELESLPPTIGYLHSLRTLAVDENFLPELPREIGSCK-----------------------NVTVMSLRSNKLEFLPEEIGQMQRLRVLNLSDNRLKNLPFSF 425
BLAST of Roc domain-containing protein vs. Ensembl Mouse
Match: Lrrc7 (leucine rich repeat containing 7 [Source:MGI Symbol;Acc:MGI:2676665]) HSP 1 Score: 80.4925 bits (197), Expect = 9.359e-15 Identity = 81/321 (25.23%), Postives = 143/321 (44.55%), Query Frame = 3
Query: 219 INLSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDSNMESLLQSGQILSDHISNTIFDLPAVQAVEMEFCKINYFKSFQS-----KALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISL 1166
I S ++ +P + + +T L +++ ++ LPA+ LV L +L + N + LPKSM L L+ L++ +P + +I +L +L + N + L IG L L +L+ ++T+ +I GCE LE LLL N++Q +P + + L TL K+D N ++L NTI +L ++ + C N +S +L L + NF E+P + + N+T + L+ N++E + + + QM+ L+VL+LS N++K L S
Sbjct: 125 IEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELREN--------HLKTLPKSMHKLAQLERLDLGNNEFSELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTL---------KVDDNQLTML----------PNTIGNLSLLEEFD---CSCNELESLPPTIGYLHSLRTLAVDENFLPELPREIGSCK-----------------------NVTVMSLRSNKLEFLPEEIGQMQRLRVLNLSDNRLKNLPFSF 392
BLAST of Roc domain-containing protein vs. UniProt/SwissProt
Match: sp|A7SFP1|SHOC2_NEMVE (Leucine-rich repeat protein soc-2 homolog OS=Nematostella vectensis OX=45351 GN=v1g189306 PE=3 SV=1) HSP 1 Score: 87.0409 bits (214), Expect = 3.694e-16 Identity = 64/176 (36.36%), Postives = 92/176 (52.27%), Query Frame = 3
Query: 210 FKSINLSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNV-IQTIPYLLADIGSLKTLSI 734
+N+ + LT +P+ I + LNV+ N I LP DI LVNLEVL +S N + LP+ + L+ L+ L+I E L IP I + SL +L + N +G L IG L + +L+ L ++PQEI E LE L L N +Q++PY L GSL+ +SI
Sbjct: 367 LSKLNVKDNQLTSLPLDFGSWISLVELNVATNQISKLPEDIQWLVNLEVLILSNN--------LLKKLPRGIGALRKLRVLDIEENKLESIPTEIEYLRSLERLVLQSNCLGSLPRSIGYLSSVTYLSVGENELVSVPQEIGNMESLEQLYLNDNENLQSLPYELVLCGSLQIMSI 534 HSP 2 Score: 82.0333 bits (201), Expect = 1.094e-14 Identity = 108/466 (23.18%), Postives = 197/466 (42.27%), Query Frame = 3
Query: 177 NRDARKNNEDDFKSINLSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPK---------------------------------------SMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSI---NLRHLGEKIDSNMESLLQSGQILSDHISNTIFDL-PAVQAVEMEFCKINYF-----------------KSFQSK-------------------ALLELHISGNFFQEIPETV---LNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISLDYYNKSLETLKXXXXXXXXXXXXXXYLEKLENLDVSSNNISELPLDLCLMKNIK 1328
+++ +K E+ ++LS A+TV+P L + + L + N I LP ++ L NLE L +S N T PD++ L K + NLK L+ L++ E + +P I ++ L LDIS N+I L ++IGN + L+ QH + +LP I + L L N + ++P LA+ + +I N+ L EK+ S++++L S +S F++ PA +FC++N F + SK +L+EL+++ N ++PE + +NL L L N ++K+ + + ++ L+VLD+ NK++ + ++Y +SLE L + N + ++P I YL + L V N + +P ++ M++++
Sbjct: 77 HKEIQKCREEGATRLDLSKAAVTVLPKELKELTSLRELYLYGNRIAVLPPEVGLLPNLETLALSENNL-TTLPDNLVKLTKLKVLDLRHNKIKEIPDVIYKLTTLTTLYLRFNRISVVESGIGNLKLLERLSLRENKIKILPRVIGQLVHLVTLDISHNHIENLPAEIGNCVHMTSLDLQHNDIPSLPDSIGRLTAMTRLGLRYNQLSSLPDSLANCSGIDEFNIEGNNIAELPEKLLSSLKNL------TSLTLSRNKFEVFPA--GPPKQFCQVNTFIMEHNRMQKIPFGVFNKAKYLSKLNVKDNQLTSLPLDFGSWISLVELNVATNQISKLPEDIQWLVNLE--------------------------VLILSNNLLKKLPRGIGALRKLRVLDIEENKLESIPTEIEYL-RSLERLVLQSNCLGSLPRSIGYLSSVTYLSVGENELVSVPQEIGNMESLE 506
BLAST of Roc domain-containing protein vs. UniProt/SwissProt
Match: sp|O61967|LAP1_CAEEL (Protein lap1 OS=Caenorhabditis elegans OX=6239 GN=let-413 PE=1 SV=3) HSP 1 Score: 84.7297 bits (208), Expect = 1.986e-15 Identity = 94/331 (28.40%), Postives = 169/331 (51.06%), Query Frame = 3
Query: 261 LFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDS----NM---------------ESLLQSGQILSDHIS-NTIFDLPA----VQAVEMEFCKINYFKSFQS-----KALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISL 1166
LF + L+VS+N + LPA+I +L L LN++RN + LP +M+N K L LN+S +P TI E +S+ L +++ ++ L S+IG+L L+ L A+ L+T+P IV KLE L L N ++ +P + + SL+ +++ L DS M E+L + + +IS N I +LP+ ++ ++M N + S ++L EL++ NF ++P+T+ +L L L++ N L +I D + ++LT L L+ N + ++ ++ + ++L VLD++ NK+ L ++
Sbjct: 55 LFSLRHLRILDVSDNELAVLPAEIGNLTQLIELNLNRNS--------IAKLPDTMQNCKLLTTLNLSSNPFTRLPETICECSSITILSLNETSLTLLPSNIGSLTNLRVLEARDNLLRTIPLSIVELRKLEELDLGQNELEALPAEIGKLTSLREFYVDINSLTSLPDSISGCRMLDQLDVSENQIIRLPENLGRMPNLTDLNISINEIIELPSSFGELKRLQMLKADRNSLHNLTSEIGKCQSLTELYLGQNFLTDLPDTIGDLRQLTTLNVDCNNLSDIPDTIGNCKSLTVLSLRQNILTELPMTIGKCENLTVLDVASNKLPHLPFTV 377 HSP 2 Score: 56.6102 bits (135), Expect = 1.103e-6 Identity = 45/170 (26.47%), Postives = 78/170 (45.88%), Query Frame = 3
Query: 219 INLSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTL 728
+++S + +P L + +T LN+S N I LP+ +L L++L RN H L + + L L + + L +P TI ++ L L++ NN+ ++ IGN L L+ + L LP I CE L L + N + +P+ + + L+ L
Sbjct: 225 LDVSENQIIRLPENLGRMPNLTDLNISINEIIELPSSFGELKRLQMLKADRNSLHN--------LTSEIGKCQSLTELYLGQNFLTDLPDTIGDLRQLTTLNVDCNNLSDIPDTIGNCKSLTVLSLRQNILTELPMTIGKCENLTVLDVASNKLPHLPFTVKVLYKLQAL 386 HSP 3 Score: 54.6842 bits (130), Expect = 3.870e-6 Identity = 88/348 (25.29%), Postives = 169/348 (48.56%), Query Frame = 3
Query: 276 EITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDSNMESL-----LQSGQILSDHISNTIFDLPAVQAVEMEFCKINYFKSFQSK--ALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISLDYYNKSLETLKXXXXXXXXXXXXXXYLEKLENLDVSSNNISELP 1298
++ ++ S++N++++P+DI LE LN++ M N+K L + ++ + L LD+S N + L ++IGNL QL LN + LP + C+ L TL L N +P + + S+ LS+N L + SN+ SL L++ L I +I +L ++ +++ ++ + K +L E ++ N +P+++ L LD+S+N ++ + ++L ++ NLT L + N+I ++ S ++K L++L N + LT + +SL L + N + ++P+ I L +L L+V NN+S++P
Sbjct: 14 QVDSIDRSQSNLQAIPSDIFRFRKLEDLNLT------------------MNNIKELDH-------------RLFSLRHLRILDVSDNELAVLPAEIGNLTQLIELNLNRNSIAKLPDTMQNCKLLTTLNLSSNPFTRLPETICECSSITILSLNETSL-TLLPSNIGSLTNLRVLEARDNLLRTIPLSIVELRKLEELDLGQNELEALPAEIGKLTSLREFYVDINSLTSLPDSISGCRMLDQLDVSENQIIRLPENLGRMPNLTDLNISINEIIELPSSFGELKRLQMLKADRNSLHNLTSEIGKC-QSLTELYLGQNFLTDLPDTIGDLRQLTTLNVDCNNLSDIP 328
BLAST of Roc domain-containing protein vs. UniProt/SwissProt
Match: sp|P0C895|Y2010_ARATH (LRR repeats and ubiquitin-like domain-containing protein At2g30105 OS=Arabidopsis thaliana OX=3702 GN=At2g30105 PE=1 SV=1) HSP 1 Score: 82.4185 bits (202), Expect = 3.300e-15 Identity = 60/186 (32.26%), Postives = 100/186 (53.76%), Query Frame = 3
Query: 192 KNNEDDFKS---INLSNTALTVVPVTLFK-RIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSIN 737
KN D +K+ I L+ L +P ++ + L++SEN IK +PA IS +++ L + NG D +I + + +LK L L+IS NL +P+ + +TSL QLD++ N + L +++G L QL+ L A + + +LP+ I C L + L N+I +P + +LKTL +N
Sbjct: 122 KNRTDRWKATGVIALAQANLKEIPEEVWDCGSGVRVLDISENFIKEVPAKISSFGSMQKLFLQGNGLS-----DESIQWEGIASLKRLMLLSISHNNLTVLPSAMGSLTSLRQLDVTNNKLTSLPNELGLLTQLEILKANNNRITSLPESIGNCSFLMEVDLSANIISELPETFTKLRNLKTLELN 302
BLAST of Roc domain-containing protein vs. UniProt/SwissProt
Match: sp|B0W6M9|SUR8_CULQU (Leucine-rich repeat protein soc-2 homolog OS=Culex quinquefasciatus OX=7176 GN=Sur-8 PE=3 SV=1) HSP 1 Score: 83.9593 bits (206), Expect = 3.469e-15 Identity = 113/439 (25.74%), Postives = 203/439 (46.24%), Query Frame = 3
Query: 180 RDARKNNEDDFKSINLSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWE-----------------------ITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLS----------INLR---HLGE-KIDSNMESLLQSGQILS---------------DHISNTIFDLPAVQAVEME---FCKINYFKSFQSKALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISLDYYNKSLETLKXXXXXXXXXXXXXXYLEKLENLDVSSNNISELPLDLCLMKNIKT 1331
++ ++ E++ ++LS +++TV+P ++ + + N I SLP +I L NL+ L ++ N +T LP S++NLK LK L++ L IP I++ ++SL L + +N I EL + IG+L L L+ H LK LP+ I C L L L N + IP + ++ +L+ L ++LR H+ E ++ N S L G + S + S V ++ ME KI Y ++K L +L++ N +P + + + L+ N L + DD+ L+NL L L N +++I ++ +K L+VLDL N+++ L + + L+ L + N ++++P I +L L L V NN+ LP ++ ++N+++
Sbjct: 139 KEFQRCKEENILRLDLSKSSITVIPPSVKDCTSLIEFYLYGNKISSLPVEIGCLSNLKTLALNEN--------SLTSLPDSLQNLKALKVLDLRHNKLSEIPDVIYKLHTLTTLYLRFNRIKVVGDNLKNLSSLTMLSLRENKIHELPAAIGHLRNLTTLDLSHNHLKHLPEAIGNCVNLTALDLQHNDLLDIPETIGNLANLQRLGLRYNQLTAIPVSLRNCIHMDEFNVEGNSISQLPDGLLASLSNLTTITLSRNAFHSYPSGGPAQFTNVTSINMEHNQIDKIQYGIFSRAKGLTKLNMKENALTSLPLDIGTWSQMVELNFGTNSLAKLPDDIHCLQNLEILILSNNMLKRIPNTIGNLKKLRVLDLEENRLESLPSEIGLLH-DLQKLILQSNALQSLPRTIGHLTNLTYLSVGENNLQYLPEEIGTLENLES 568 HSP 2 Score: 61.2326 bits (147), Expect = 3.859e-8 Identity = 55/178 (30.90%), Postives = 87/178 (48.88%), Query Frame = 3
Query: 207 DFKSINLSNTALTVVPVTLFKRIE-ITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSIN 737
+ SIN+ + + + +F R + +T LN+ EN + SLP DI + LN N + LP + L+ L+ L +S L IP TI + L LD+ +N + L S+IG L LQ L Q L++LP+ I L L + N +Q +P + + +L++L IN
Sbjct: 403 NVTSINMEHNQIDKIQYGIFSRAKGLTKLNMKENALTSLPLDIGTWSQMVELNFGTN--------SLAKLPDDIHCLQNLEILILSNNMLKRIPNTIGNLKKLRVLDLEENRLESLPSEIGLLHDLQKLILQSNALQSLPRTIGHLTNLTYLSVGENNLQYLPEEIGTLENLESLYIN 572 HSP 3 Score: 57.3806 bits (137), Expect = 5.885e-7 Identity = 41/139 (29.50%), Postives = 75/139 (53.96%), Query Frame = 3
Query: 225 LSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKN-NIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVG 638
LSN L +P T+ ++ L++ EN ++SLP++I L +L+ L + N LP+++ +L L YL++ E NL ++P I + +L L I+ N ++ +L ++ L ++ ++C L LP E+VG
Sbjct: 479 LSNNMLKRIPNTIGNLKKLRVLDLEENRLESLPSEIGLLHDLQKLILQSNALQS--------LPRTIGHLTNLTYLSVGENNLQYLPEEIGTLENLESLYINDNASLVKLPYELALCQNLAIMSIENCPLSALPPEVVG 609
BLAST of Roc domain-containing protein vs. UniProt/SwissProt
Match: sp|Q96NW7|LRRC7_HUMAN (Leucine-rich repeat-containing protein 7 OS=Homo sapiens OX=9606 GN=LRRC7 PE=1 SV=1) HSP 1 Score: 82.4185 bits (202), Expect = 1.865e-14 Identity = 82/321 (25.55%), Postives = 144/321 (44.86%), Query Frame = 3
Query: 219 INLSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDSNMESLLQSGQILSDHISNTIFDLPAVQAVEMEFCKINYFKSFQS-----KALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISL 1166
I S ++ +P + + +T L +++ ++ LPA+ LV L +L + N + LPKSM L L+ L++ +P + +I +L +L + N + L IG L L +L+ ++T+ +I GCE LE LLL N++Q +P + + L TL K+D N ++L NTI +L ++ + C N +S S +L L + NF E+P + + N+T + L+ N++E + + + QM+ L+VL+LS N++K L S
Sbjct: 120 IEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELREN--------HLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTL---------KVDDNQLTML----------PNTIGNLSLLEEFD---CSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGSCK-----------------------NVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSDNRLKNLPFSF 387
BLAST of Roc domain-containing protein vs. TrEMBL
Match: A0A1S3IFK1 (malignant fibrous histiocytoma-amplified sequence 1 homolog isoform X2 OS=Lingula unguis OX=7574 GN=LOC106163857 PE=4 SV=1) HSP 1 Score: 348.591 bits (893), Expect = 1.093e-99 Identity = 263/924 (28.46%), Postives = 479/924 (51.84%), Query Frame = 3
Query: 195 NNEDDF-KSINLSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDSNMESLLQSGQILSDHISNTIFDLPAVQAVEMEFCKINYFKSFQSKALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISLDYYNKSLETLKXXXXXXXXXXXXXXYLEKLENLDVSSNNISELPLDLCLMKNIKTAHYFNGLHRIGLWVSSNPIEFPPKCVWNTTNIDVIYSFLQKTKIKRLQIKSPIRVVLIGDN-SIKDNFLERFLGKRIS-----NDSEYLTINQW-TSENSVPFVLVNVNCHPTYVMHIRHYMEDNAFIWIFIDH--FKTKNLLKESEKWIDLVMEYSTDCVIQIV-----------------------IVNYFENNSEDIFQNFVNFSD----KKLIES-----------LRER------FSNEKVNILPNILLISPGESLNAFKD---DLEYIAIDKDLFQSDEMFNIFTRETKAIENICKSTKCIYVNLNDLISKIREMFPFPTDSIFSCLKCLHKQGKILWFYKNKKLSNKIYPFISLFNKSIRSLIRLDYEEDLDFAKNPLIKAKGLMNGEKFEQVKKSFLKYGEICYPLYKVLTF----EFQELRSVKDFLIDANIAWGVPLS-VDLEEDIFQRPFVVLAQFNKEKFDKSCFLDS-----ILKKESANIDYGFTIRSTSLSDHSNLFLNLKCEVNCWAVRRYDWMNAVYLHHNNGDVLL 2765
++ED + + ++LSN LT V F ++ +N+S N ++++P DI L +L LNISRNG C+ P+D LP + +LK L+ L I+ECNL +IP +W + L +LDIS+N I L +IG+L +L++LN Q G+ TLP EI C++L+ +LLYGN ++++P L ++ L L +N R +D ME+L++ GQI S+H+ +F++P ++++E CKIN +L+E +IS N+F ++P+ + + NLQ LD+S N++ ++ D+ +L+++ L + N E + S+ +K L+VL++ N+I+ L + +L TLK+ NNI+ +P+ I L +LE LD++ N ++ LPL+L + + +AH ++ L + GLW++ NP+ PP+ VW TT+I IY +LQ+ KI R Q+ ++++L+G++ S K + + +I+ DS + ++ T+EN V F++ ++ P Y+ +++ A + I DH + + KWIDL+ + V++IV + + E + E + + + +D +K IE+ L E+ V ++P I ++S E D ++E +A++++LF +I E ++ + K +++ D+ +I + F F + + CL L G ++WF + +L + I+ F + +R + + + E LD+ KN + +KG + FE+ +K FL++G++ + + L F + E ++ DF+ +I + +P + L + FQ PF + +NK+ D S +L + +DY F + LF L + R DW + Y + +LL
Sbjct: 93 HHEDKYLRVVDLSNQGLTTVQSAYFNAKDVGEMNLSGNCLRTIPLDIRKLTHLISLNISRNGIKCSHPNDYGGLPAELDSLKFLETLIIAECNLQYIPPAVWRLKKLKKLDISRNKIQILVPEIGHLTKLEYLNLQQTGITTLPLEIAYCQELQQILLYGNAMESLPETLKELPYLCVLKMNHRSFCSVVDDYMENLIRKGQIQSEHVPQVLFEMPCPLSLDLEACKINNLPDECPNSLIEFNISKNYFHDVPKALYRIENLQYLDMSNNMISDLPQDIGQLKSVKVLKINSNVFETVPPSIGDLKHLEVLEMESNRIRCLPSEISNLT-TLHTLKLAKNNIQALPDSICELYRLETLDLTDNGLTSLPLNLYKLSRLTSAHSYHLLFKTGLWLNKNPLVTPPEHVWKTTDIQKIYVYLQQLKIARTQLLR-LKLILMGESQSGKTSLANAMISGKINLTAGKEDSTSIVEQRFLTTENGVNFMVYDLGGDPVYMFTHPMFLDPKALMMILYDHSTYNPDSFQSTIGKWIDLINVRTPGAVVKIVGTHTDLCEDEKVSQAKLQLIQEQVKKHQEEHEESLNKELESITDQIEKQKTIETDINFETPAAEFLEEQQKKIEGLLQNTVKMMP-ISIVSSTEGTKGVADVMAEMERLAVNENLF--PHAHDIVDPEWDDFKSALRLHKTLFLTW-DMAVEIGKSFKFDEEEVLHCLLYLRDTGDVVWFRGSSQLHDVIFHRPKYFVQVLRGIFKHNMEAFLDYEKNKVFSSKGKYEPDIFEEHRKMFLQHGQVSRQMMQCLWFYLKLGYDEFYALMDFIPRLDILYAIPQPDLPLAKHHFQ-PFAAIPWYNKDAEDISTVKGYWTPKLLLDIKELKVDYTFPLYYP-----VGLFERLSVRIQDIITERIDWKSLTYATTEDEQLLL 1004
BLAST of Roc domain-containing protein vs. TrEMBL
Match: A0A1S3IGL4 (malignant fibrous histiocytoma-amplified sequence 1 homolog isoform X1 OS=Lingula unguis OX=7574 GN=LOC106163857 PE=4 SV=1) HSP 1 Score: 348.206 bits (892), Expect = 1.947e-99 Identity = 263/924 (28.46%), Postives = 479/924 (51.84%), Query Frame = 3
Query: 195 NNEDDF-KSINLSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDSNMESLLQSGQILSDHISNTIFDLPAVQAVEMEFCKINYFKSFQSKALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISLDYYNKSLETLKXXXXXXXXXXXXXXYLEKLENLDVSSNNISELPLDLCLMKNIKTAHYFNGLHRIGLWVSSNPIEFPPKCVWNTTNIDVIYSFLQKTKIKRLQIKSPIRVVLIGDN-SIKDNFLERFLGKRIS-----NDSEYLTINQW-TSENSVPFVLVNVNCHPTYVMHIRHYMEDNAFIWIFIDH--FKTKNLLKESEKWIDLVMEYSTDCVIQIV-----------------------IVNYFENNSEDIFQNFVNFSD----KKLIES-----------LRER------FSNEKVNILPNILLISPGESLNAFKD---DLEYIAIDKDLFQSDEMFNIFTRETKAIENICKSTKCIYVNLNDLISKIREMFPFPTDSIFSCLKCLHKQGKILWFYKNKKLSNKIYPFISLFNKSIRSLIRLDYEEDLDFAKNPLIKAKGLMNGEKFEQVKKSFLKYGEICYPLYKVLTF----EFQELRSVKDFLIDANIAWGVPLS-VDLEEDIFQRPFVVLAQFNKEKFDKSCFLDS-----ILKKESANIDYGFTIRSTSLSDHSNLFLNLKCEVNCWAVRRYDWMNAVYLHHNNGDVLL 2765
++ED + + ++LSN LT V F ++ +N+S N ++++P DI L +L LNISRNG C+ P+D LP + +LK L+ L I+ECNL +IP +W + L +LDIS+N I L +IG+L +L++LN Q G+ TLP EI C++L+ +LLYGN ++++P L ++ L L +N R +D ME+L++ GQI S+H+ +F++P ++++E CKIN +L+E +IS N+F ++P+ + + NLQ LD+S N++ ++ D+ +L+++ L + N E + S+ +K L+VL++ N+I+ L + +L TLK+ NNI+ +P+ I L +LE LD++ N ++ LPL+L + + +AH ++ L + GLW++ NP+ PP+ VW TT+I IY +LQ+ KI R Q+ ++++L+G++ S K + + +I+ DS + ++ T+EN V F++ ++ P Y+ +++ A + I DH + + KWIDL+ + V++IV + + E + E + + + +D +K IE+ L E+ V ++P I ++S E D ++E +A++++LF +I E ++ + K +++ D+ +I + F F + + CL L G ++WF + +L + I+ F + +R + + + E LD+ KN + +KG + FE+ +K FL++G++ + + L F + E ++ DF+ +I + +P + L + FQ PF + +NK+ D S +L + +DY F + LF L + R DW + Y + +LL
Sbjct: 109 HHEDKYLRVVDLSNQGLTTVQSAYFNAKDVGEMNLSGNCLRTIPLDIRKLTHLISLNISRNGIKCSHPNDYGGLPAELDSLKFLETLIIAECNLQYIPPAVWRLKKLKKLDISRNKIQILVPEIGHLTKLEYLNLQQTGITTLPLEIAYCQELQQILLYGNAMESLPETLKELPYLCVLKMNHRSFCSVVDDYMENLIRKGQIQSEHVPQVLFEMPCPLSLDLEACKINNLPDECPNSLIEFNISKNYFHDVPKALYRIENLQYLDMSNNMISDLPQDIGQLKSVKVLKINSNVFETVPPSIGDLKHLEVLEMESNRIRCLPSEISNLT-TLHTLKLAKNNIQALPDSICELYRLETLDLTDNGLTSLPLNLYKLSRLTSAHSYHLLFKTGLWLNKNPLVTPPEHVWKTTDIQKIYVYLQQLKIARTQLLR-LKLILMGESQSGKTSLANAMISGKINLTAGKEDSTSIVEQRFLTTENGVNFMVYDLGGDPVYMFTHPMFLDPKALMMILYDHSTYNPDSFQSTIGKWIDLINVRTPGAVVKIVGTHTDLCEDEKVSQAKLQLIQEQVKKHQEEHEESLNKELESITDQIEKQKTIETDINFETPAAEFLEEQQKKIEGLLQNTVKMMP-ISIVSSTEGTKGVADVMAEMERLAVNENLF--PHAHDIVDPEWDDFKSALRLHKTLFLTW-DMAVEIGKSFKFDEEEVLHCLLYLRDTGDVVWFRGSSQLHDVIFHRPKYFVQVLRGIFKHNMEAFLDYEKNKVFSSKGKYEPDIFEEHRKMFLQHGQVSRQMMQCLWFYLKLGYDEFYALMDFIPRLDILYAIPQPDLPLAKHHFQ-PFAAIPWYNKDAEDISTVKGYWTPKLLLDIKELKVDYTFPLYYP-----VGLFERLSVRIQDIITERIDWKSLTYATTEDEQLLL 1020
BLAST of Roc domain-containing protein vs. TrEMBL
Match: A0A267GL57 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig031151g2 PE=4 SV=1) HSP 1 Score: 322.783 bits (826), Expect = 5.603e-91 Identity = 233/796 (29.27%), Postives = 402/796 (50.50%), Query Frame = 3
Query: 183 DARKNNEDDFKSINLSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDSNMESLLQSGQILSDHISNTIFDLPAVQAVEMEFCKINYFKSFQSKALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISLDYYNKSLETLKXXXXXXXXXXXXXXYLEKLENLDVSSNNISELPLDLCLMKNIKTAHYFNGLHRIGLWVSSNPIEFPPKCVWNTTNIDVIYSFLQKTKIKRLQIKSPIRVVLIGDNSIKDNFLERFL----GKRISNDSEYLT----INQWTSENSVPFVLVNVNCHPTYVMHIRHYMEDNAFIWIFIDHFKTKNL-LKESEKWIDLVMEYSTDCVIQIVIVN--------------------------YFENNSEDIFQNFVNFSDKKL---IESLRERFSNEKVNILPNILLIS----PGES-LNAFKDDLEYIAIDKDLFQSDEMFNIFTRETKAIENICKSTKCIYVNLNDLIS-----KIREMFPFPTDSIFSCLKCLHKQGKILWFYKNKKLSNKIYPFISLFNKSIRSLIRLDYEEDL-DFAKNPLIKAKGLMNGEKFEQVKKSFLKYGEICYPLYKVLTF 2423
+ R +E DF S+ LT+ P +LF + IT LN+S NNI+ LP +IS+L L L++SRNG C P D T LPK M+ + L+ L +SEC+L+ IP +W I L +LDIS+N +G + SDI L++L LNA G+KTLP+EIV C+ LE+LLL+GN I ++P L ++ L TL IN R +D+ + +LQ Q+ S+HI + +F +P + +++E CK+N +++L+EL+I+ N+F PE V +L L +LD+S+N + L L +L L + NQ+ SL + L+ +DL N I KL ++ K L + + ++L+ LD++ N ++ +P ++ + + AH F+GL + GLW+ +NPI+ PP VWNT + I++ +++ I+ P ++V +GD L R L +D LT ++ W SEN PFVL+ HP Y + ++ A + D + + L +W+ L+ + +Q++ E+ +E Q + D+ L +E LR SN ++ + P I L+S P + L +DDLE ++ +++ + + + T +E + K +Y+ + L+ IR+ + CL+ H+ G++LW ++++L N + + + L+ + + L D+ +N L +A G M+ ++E+ +++ L G++ +PL + L F
Sbjct: 45 EGRSRDELDF-----SSQGLTMAPSSLFAKTHITVLNLSSNNIRGLPPEISNLTQLRHLDLSRNGLRCAHPRDFTSLPKEMETMAELRELLLSECSLMHIPPAVWSIVGLEKLDISRNKVGAIPSDIMKLERLVHLNATQTGIKTLPEEIVCCDALESLLLFGNPIDSLPDSLRELNRLHTLHINYRVFASGVDAETDGMLQRQQLTSEHIPSVVFHIPQLLEMDLEACKVNALPRSLTRSLVELNIAANYFPAFPEAVCSLRQLTLLDVSRNGFKTLPPALKDLRSLRVLLARHNQL-TFVDSLADLTELERIDLGFNCIAKLPDNIGQLTKLTALLLPGNRLDALPKSLCSLGDQLQTLDLTGNRLTSIPPEMAGLAGLDRAHQFSGLFKRGLWLHNNPIDKPPAKVWNTWDPAKIWAHMERMAIQNAPKLRPCKLVFLGDLGSGKTSLARLLRLGHAAPTKSDGSGLTRGFQLSSWRSENRCPFVLLEAGGHPIYAPLLAKLLDPKALHCVVFDIAEYQQLGFDVVSRWLRLLAAHLPGARVQLIGTKLDTISMTTETSADEILAEVSEVEAALAAESTAEAAVQRLRDSLDEDLARCLEQLRAD-SNPELRLQPRIHLVSAVGPPAQPDLLTLRDDLERLSTNREAMPHLQKY-VPTNWQPFMEQV-KQQDGLYIEWDWLVEFADQRNIRDA------QLIDCLEFYHESGQLLWLRRHRRLRNFVLHRLDKLADFLGRLLPVSLADFLVDYNENALFRACGRMSAAEYEEAREAALSRGQLSWPLVRCLAF 825
BLAST of Roc domain-containing protein vs. TrEMBL
Match: A0A1I8G548 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1) HSP 1 Score: 321.627 bits (823), Expect = 1.463e-90 Identity = 233/794 (29.35%), Postives = 400/794 (50.38%), Query Frame = 3
Query: 189 RKNNEDDFKSINLSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDSNMESLLQSGQILSDHISNTIFDLPAVQAVEMEFCKINYFKSFQSKALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISLDYYNKSLETLKXXXXXXXXXXXXXXYLEKLENLDVSSNNISELPLDLCLMKNIKTAHYFNGLHRIGLWVSSNPIEFPPKCVWNTTNIDVIYSFLQKTKIKRLQIKSPIRVVLIGDNSIKDNFLERFL----GKRISNDSEYLT----INQWTSENSVPFVLVNVNCHPTYVMHIRHYMEDNAFIWIFIDHFKTKNL-LKESEKWIDLVMEYSTDCVIQIVIVN--------------------------YFENNSEDIFQNFVNFSDKKL---IESLRERFSNEKVNILPNILLIS----PGES-LNAFKDDLEYIAIDKDLFQSDEMFNIFTRETKAIENICKSTKCIYVNLNDLIS-----KIREMFPFPTDSIFSCLKCLHKQGKILWFYKNKKLSNKIYPFISLFNKSIRSLIRLDYEEDL-DFAKNPLIKAKGLMNGEKFEQVKKSFLKYGEICYPLYKVLTF 2423
R +E DF S+ LT+ P +LF + IT LN+S NNI+ LP +IS+L L L++SRNG C P D T LPK M+ + L+ L +SEC+L+ IP +W I L +LDIS+N +G + SDI L++L LNA G+KTLP+EIV C+ LE+LLL+GN I ++P L ++ L TL IN R +D+ + +LQ Q+ S+HI + +F +P + +++E CK+N +++L+EL+I+ N+F PE V +L+ L +LD+S+N + L L +L L + NQ+ SL + LK +DL N I KL ++ K L + + ++L+ LD++ N ++ +P ++ + + AH F+GL + GLW+ NPI+ PP VWNT + I++ +++ I+ P ++V +GD L R L +D LT ++ W SEN PFVL+ HP Y + ++ A + D + + + +W+ L+ + +Q++ E+ +E Q + D+ L +E LR SN ++ + P I L+S P + L +DDLE ++ +++ + + + T +E + K +Y+ + L+ IR+ + CL+ H+ G++LW ++++L N + + L+ + + L D+ +N L +A G M+ ++E+ +++ L G++ +PL + L F
Sbjct: 47 RSRDELDF-----SSQGLTMAPSSLFAKTHITVLNLSSNNIRGLPPEISNLTQLRHLDLSRNGLRCAHPRDFTSLPKEMETMAELRELLLSECSLMHIPPAVWSIVGLEKLDISRNKVGAIPSDIMKLERLVHLNATQTGIKTLPEEIVCCDALESLLLFGNPIDSLPDSLRELNRLHTLHINYRVFASGVDAETDGMLQRQQLTSEHIPSVVFHIPQLLEMDLEACKVNALPRSLTRSLVELNIAANYFPAFPEAVCSLHQLTLLDVSRNGFKTLPPALKDLRSLRVLLARHNQL-TFVDSLADLTELKRIDLGFNCIAKLPDNIGQLTKLTALLLPGNRLDALPKSLCSLGDQLQTLDLTGNRLTSIPPEMAGLAGLDRAHQFSGLFKRGLWLHKNPIDKPPAKVWNTWDPAKIWAHMERMAIQNAPKLRPCKLVFLGDLGSGKTSLARLLRLGHAAPTKSDGSGLTRGFQLSSWRSENRCPFVLLEAGGHPIYAPLLAKLLDPKALHCVVFDIAEYQQIGFDVVSRWLRLLAAHLPGARVQLIGTKLDTISMATETSANEILAEVSEVEAALAAESTAEAAVQRLRDSLDEDLARCLEQLRAD-SNPELRLQPRIHLVSAVGPPAQPDLLTLRDDLERLSTNREAMPHLQKY-VPTNWQPFMEQV-KQQDGLYIEWDWLVEFADQRNIRDA------QLIDCLEFYHESGQLLWLRRHRRLRNFVLHRPDKLADFLGRLLPVSLADFLVDYNENALFRACGRMSAAEYEEAREAALSRGQLSWPLVRCLAF 825
BLAST of Roc domain-containing protein vs. TrEMBL
Match: A0A267G7R0 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig031151g3 PE=4 SV=1) HSP 1 Score: 321.627 bits (823), Expect = 1.477e-90 Identity = 231/795 (29.06%), Postives = 406/795 (51.07%), Query Frame = 3
Query: 183 DARKNNEDDFKSINLSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDSNMESLLQSGQILSDHISNTIFDLPAVQAVEMEFCKINYFKSFQSKALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISLDYYNKSLETLKXXXXXXXXXXXXXXYLEKLENLDVSSNNISELPLDLCLMKNIKTAHYFNGLHRIGLWVSSNPIEFPPKCVWNTTNIDVIYSFLQKTKIKRLQIKSPIRVVLIGDNSIKDNFLERFL----GKRISNDSEYLT----INQWTSENSVPFVLVNVNCHPTYVMHIRHYMEDNAFIWIFIDHFKTKNL-LKESEKWIDLVMEYSTDCVIQIV------IVNYFENNSEDIF------------QNFVNFSDKKLIESLRERF----------SNEKVNILPNILLIS----PGES-LNAFKDDLEYIAIDKDLFQSDEMFNIFTRETKAIENICKSTKCIYVNLNDLIS-----KIREMFPFPTDSIFSCLKCLHKQGKILWFYKNKKLSNKIYPFISLFNKSIRSLIRLDYEEDL-DFAKNPLIKAKGLMNGEKFEQVKKSFLKYGEICYPLYKVLTF 2423
+ R +E DF S+ LT+ P +LF + IT LN+S NNI+ LP +IS+L L L++SRNG C P D T LPK M+ + L+ L +SEC+L+ IP +W I L +LDIS+N +G + SDI L++L LNA G+KTLP+EIV C+ LE+LLL+GN I ++P L ++ L TL IN R +D+ + +LQ Q+ S+HI + +F +P + +++E CK+N +++L+EL+I+ N+F PE V +L+ L +LD+S+N + L L +L L + NQ+ SL + L+ +DL N I KL ++ K L + + ++L+ LD++ N ++ +P ++ + + AH F+GL + GLW+ +NPI+ PP VWNT + I++ +++ I+ P ++V +GD L R L +D LT ++ W SEN PFVL+ HP Y + ++ A + D + + + +W+ L+ + +Q++ I E ++++I ++ + ++L +SL E SN ++ + P I L+S P + L +DDLE ++ +++ + + + T +E + K +Y+ + L+ IR+ + CL+ H+ G++LW ++++L N + + L+ + + L D+ +N L +A G M+ ++E+ +++ L G++ +PL + L F
Sbjct: 45 EGRSRDELDF-----SSQGLTMAPSSLFAKTHITVLNLSSNNIRGLPPEISNLTQLRHLDLSRNGLRCAHPRDFTSLPKEMETMAELRELLLSECSLMHIPPAVWSIVGLEKLDISRNKVGAIPSDIMKLERLVHLNATQTGIKTLPEEIVCCDALESLLLFGNPIDSLPDSLRELNRLHTLHINYRVFASGVDAETDGMLQRQQLTSEHIPSVVFHIPQLLEMDLEACKVNALPRSLTRSLVELNIAANYFPAFPEAVCSLHQLTLLDVSRNGFKTLPPALKDLRSLRVLLARHNQL-TFVDSLADLTELERIDLGFNCIAKLPDNIGQLTKLTALLLPGNRLDALPKSLCSLGDQLQTLDLTGNRLTSIPPEMAGLAGLDRAHQFSGLFKRGLWLHNNPIDKPPAKVWNTWDPAKIWAHMERMAIQNAPKLRPCKLVFLGDLGSGKTSLARLLRLGHAAPTKSDGSGLTRGFQLSSWRSENRCPFVLLEAGGHPIYAPLLAKLLDPKALHCVVFDIAEYQQIGFDVVSRWLRLLAAHLPGARVQLIGTKLDTISMATETSADEILAEVSEVEAALAAESTAEAAVQRLRDSLDEDLARCLEQLRADSNPELRLQPRIHLVSAVGPPAQPDLLTLRDDLERLSTNREAMPHLQKY-VPTNWQPFMEQV-KQQDGLYIEWDWLVEFADQRNIRDA------QLIDCLEFYHESGQLLWLRRHRRLRNFVLHRPDKLADFLGRLLPVSLADFLVDYNENALFRACGRMSAAEYEEAREAALSRGQLSWPLVRCLAF 825
BLAST of Roc domain-containing protein vs. Ensembl Cavefish
Match: LRRC2 (leucine rich repeat containing 2 [Source:NCBI gene;Acc:103036599]) HSP 1 Score: 82.8037 bits (203), Expect = 3.143e-16 Identity = 50/176 (28.41%), Postives = 92/176 (52.27%), Query Frame = 3
Query: 207 DFKSINLSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSI 734
D + +++ T++P + K + + LNV+ N + +P ++ + NLE L ++ NG D++ LP + NLK LK+L+++E IP + ++SL LD+S N + +L DI L LQ + L LP + +KL+ L++ G+ + +P L D +K + +
Sbjct: 179 DLRVLDIPKNGFTMLPPEIGKLVNLKELNVNYNKLSIIPPELGECENLEKLEMTANG-------DLSELPFELSNLKALKHLDLAENKFATIPICVLRMSSLQWLDMSNNRLTDLPEDIDRLSDLQTMFLHKNKLTYLPMVMANMDKLKMLVVSGDELTNLPSKLCDSPDIKFIKL 347 HSP 2 Score: 52.373 bits (124), Expect = 1.937e-6 Identity = 34/109 (31.19%), Postives = 57/109 (52.29%), Query Frame = 3
Query: 411 LPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNV-IQTIPYLLADIGSLKTLSI 734
LP+ ++ + L+ +I ++ +P I E L LDI KN L +IG L L+ LN + L +P E+ CE LE L + N + +P+ L+++ +LK L +
Sbjct: 147 LPEDLQIMTFLREWHIRGTSIQKVPTYIEEFVDLRVLDIPKNGFTMLPPEIGKLVNLKELNVNYNKLSIIPPELGECENLEKLEMTANGDLSELPFELSNLKALKHLDL 255
BLAST of Roc domain-containing protein vs. Ensembl Cavefish
Match: LRRC2 (leucine rich repeat containing 2 [Source:NCBI gene;Acc:103036599]) HSP 1 Score: 82.4185 bits (202), Expect = 3.983e-16 Identity = 50/176 (28.41%), Postives = 92/176 (52.27%), Query Frame = 3
Query: 207 DFKSINLSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSI 734
D + +++ T++P + K + + LNV+ N + +P ++ + NLE L ++ NG D++ LP + NLK LK+L+++E IP + ++SL LD+S N + +L DI L LQ + L LP + +KL+ L++ G+ + +P L D +K + +
Sbjct: 179 DLRVLDIPKNGFTMLPPEIGKLVNLKELNVNYNKLSIIPPELGECENLEKLEMTANG-------DLSELPFELSNLKALKHLDLAENKFATIPICVLRMSSLQWLDMSNNRLTDLPEDIDRLSDLQTMFLHKNKLTYLPMVMANMDKLKMLVVSGDELTNLPSKLCDSPDIKFIKL 347 HSP 2 Score: 51.9878 bits (123), Expect = 2.326e-6 Identity = 34/109 (31.19%), Postives = 57/109 (52.29%), Query Frame = 3
Query: 411 LPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNV-IQTIPYLLADIGSLKTLSI 734
LP+ ++ + L+ +I ++ +P I E L LDI KN L +IG L L+ LN + L +P E+ CE LE L + N + +P+ L+++ +LK L +
Sbjct: 147 LPEDLQIMTFLREWHIRGTSIQKVPTYIEEFVDLRVLDIPKNGFTMLPPEIGKLVNLKELNVNYNKLSIIPPELGECENLEKLEMTANGDLSELPFELSNLKALKHLDL 255
BLAST of Roc domain-containing protein vs. Ensembl Cavefish
Match: LRRC2 (leucine rich repeat containing 2 [Source:NCBI gene;Acc:103036599]) HSP 1 Score: 82.8037 bits (203), Expect = 4.097e-16 Identity = 50/176 (28.41%), Postives = 92/176 (52.27%), Query Frame = 3
Query: 207 DFKSINLSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSI 734
D + +++ T++P + K + + LNV+ N + +P ++ + NLE L ++ NG D++ LP + NLK LK+L+++E IP + ++SL LD+S N + +L DI L LQ + L LP + +KL+ L++ G+ + +P L D +K + +
Sbjct: 216 DLRVLDIPKNGFTMLPPEIGKLVNLKELNVNYNKLSIIPPELGECENLEKLEMTANG-------DLSELPFELSNLKALKHLDLAENKFATIPICVLRMSSLQWLDMSNNRLTDLPEDIDRLSDLQTMFLHKNKLTYLPMVMANMDKLKMLVVSGDELTNLPSKLCDSPDIKFIKL 384 HSP 2 Score: 52.373 bits (124), Expect = 1.811e-6 Identity = 34/109 (31.19%), Postives = 57/109 (52.29%), Query Frame = 3
Query: 411 LPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNV-IQTIPYLLADIGSLKTLSI 734
LP+ ++ + L+ +I ++ +P I E L LDI KN L +IG L L+ LN + L +P E+ CE LE L + N + +P+ L+++ +LK L +
Sbjct: 184 LPEDLQIMTFLREWHIRGTSIQKVPTYIEEFVDLRVLDIPKNGFTMLPPEIGKLVNLKELNVNYNKLSIIPPELGECENLEKLEMTANGDLSELPFELSNLKALKHLDL 292
BLAST of Roc domain-containing protein vs. Ensembl Cavefish
Match: lrrc7 (leucine rich repeat containing 7 [Source:ZFIN;Acc:ZDB-GENE-130530-876]) HSP 1 Score: 83.1889 bits (204), Expect = 1.015e-15 Identity = 87/335 (25.97%), Postives = 147/335 (43.88%), Query Frame = 3
Query: 249 VPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFH----------C-----TSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLD---------ISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDSNMESLLQSGQILS-----DHISNTIFDLPAVQAVEMEFCKINYFKSFQSKALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISL 1166
+P LF + L++ +N++ SLP I+ LVNL+ L+IS+NG C S + +T LP L L L +++ L ++PA ++ L L+ + N++ + IG L QL++L+ +++L +I GCE LE LLL N++Q +P + + L TL ++ D+ + SL + LS D N + LP I Y S ++ A E NF E+P + N N+T + L+ N++E + + QM L+VL+LS N+++ L +
Sbjct: 66 LPKQLFNCQALRKLSIPDNDLSSLPTTIASLVNLKELDISKNGIQEFPDNIKCCKCLSVVEASVNPITKLPDGFTQLLNLTQLFLNDAFLEYLPANFGRLSKLQVLEQIHNLKELWLDNNSLQTIPGSIGKLRQLRYLDLAKNRIESLDADISGCESLEDLLLSSNMLQQLPDTIGMLKKLTTLKVD--------DNQLTSLPNTIGSLSLLEEFDCSCNELESLPPT---------IGYLHSLRTFAADE-----NFLTELPREIGNCR-----------------------NVTVMSLRSNKLEFLPDEIGQMTKLRVLNLSDNRLRNLPYTF 355 HSP 2 Score: 61.2326 bits (147), Expect = 6.264e-9 Identity = 54/190 (28.42%), Postives = 90/190 (47.37%), Query Frame = 3
Query: 207 DFKSINLSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPD----------------DMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTL 728
+ K + L N +L +P ++ K ++ +L++++N I+SL ADIS +LE L +S N PD +T LP ++ +L L+ + S L +P TI + SL +N + EL +IGN + ++ + L+ LP EI KL L L N ++ +PY + L L
Sbjct: 176 NLKELWLDNNSLQTIPGSIGKLRQLRYLDLAKNRIESLDADISGCESLEDLLLSSNMLQQL-PDTIGMLKKLTTLKVDDNQLTSLPNTIGSLSLLEEFDCSCNELESLPPTIGYLHSLRTFAADENFLTELPREIGNCRNVTVMSLRSNKLEFLPDEIGQMTKLRVLNLSDNRLRNLPYTFTKLKDLAAL 364
BLAST of Roc domain-containing protein vs. Ensembl Cavefish
Match: erbin (erbb2 interacting protein [Source:ZFIN;Acc:ZDB-GENE-061103-403]) HSP 1 Score: 78.5666 bits (192), Expect = 1.753e-14 Identity = 76/323 (23.53%), Postives = 143/323 (44.27%), Query Frame = 3
Query: 219 INLSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDSNMESLLQSGQILSDHISNTIFDLPAVQAVEMEFCKINYFKSF--QSKALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISLDYYNK 1181
+ S ++ +P + + +T L +++ ++ LPA L L++L + N + +LPKSM L L+ L++ +P + ++T + +L + N + + +G L QL +L+ ++ + ++I GCE L+ LLL N + +P IGSLK L+ K+D N Q++ + ++I L A+ ++ F +I + Q L NF ++P + +N T L+L N++E + + + M+ LKV++LS NK+K L S N+
Sbjct: 108 VEASVNPISKLPEGFTQLLSLTQLYLNDAFLEFLPASFGRLTKLQILELREN--------QLKMLPKSMHKLTQLERLDLGSNEFTEVPEVLEQLTGIKELWMDGNKLTMVPGMVGMLKQLTYLDVSKNNVELVDEQINGCENLQDLLLSNNALTQLP---GSIGSLKKLT------ALKVDEN--------QLVC--LPDSIGGLSALDELDCSFNEIESLPAAIGQCVNLRTFAADHNFLSQLPPEM-----------------------GCWKNATVLFLHSNKLESLPEEMGDMQKLKVVNLSDNKLKNLPYSFTKLNQ 380 HSP 2 Score: 76.6406 bits (187), Expect = 7.050e-14 Identity = 57/176 (32.39%), Postives = 97/176 (55.11%), Query Frame = 3
Query: 213 KSINLSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLL-LYGNVIQTIPYLLADIGSLKTLSIN 737
K + + LT+VP + ++T+L+VS+NN++ + I+ NL+ L +S N +T LP S+ +LK L L + E LV +P +I +++L +LD S N I L + IG L+ A H L LP E+ GC K T+L L+ N ++++P + D+ LK ++++
Sbjct: 198 KELWMDGNKLTMVPGMVGMLKQLTYLDVSKNNVELVDEQINGCENLQDLLLSNNA--------LTQLPGSIGSLKKLTALKVDENQLVCLPDSIGGLSALDELDCSFNEIESLPAAIGQCVNLRTFAADHNFLSQLPPEM-GCWKNATVLFLHSNKLESLPEEMGDMQKLKVVNLS 364
BLAST of Roc domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004940.1 (pep scaffold:Pmarinus_7.0:GL476356:339323:347865:-1 gene:ENSPMAG00000004448.1 transcript:ENSPMAT00000004940.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 71.2478 bits (173), Expect = 6.106e-13 Identity = 104/380 (27.37%), Postives = 184/380 (48.42%), Query Frame = 3
Query: 216 SINLSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSI---NLRHLGEK---IDSNMESLLQSGQILSDHISNTIFDLPAVQAVEME---FCKINYFKSFQSKALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISLDYYNKSLETLKXXXXXXXXXXXXXXYLEKLENLDVSSNNISELPLDLCLMKNIK 1328
++ L+ +LT +P TL + L++ N ++S+P + L +L VL + N +T + K + NL L L++ E + +PA I E+ SL LD++ N + L +IGN Q+ L+ QH L LP I L L L N + +P LA+ L+ L++ N+ L E N+ SL + + V ++ ME KI + ++KAL +L++ N +P + ++ L+L+ N L I DD+ +L +L L L N + K+ L ++ L+ LDL NK++ L + Y K L+ L + +N + ++P I +L L +L V N ++ +P ++ ++N++
Sbjct: 99 TLALNENSLTGLPDTLTGLTSLRMLDLRHNKLRSIPPVVYRLTSLTVLYLRFN--------RITQVEKDIGNLSKLTMLSVRENKIKLLPAEIGELRSLLTLDVAHNQLEHLPEEIGNCVQVTNLDLQHNELLDLPDSIGNLASLNRLGLRYNRLSAVPTTLANCTELEDLNLENNNISTLPEGLLSSLVNLSSLTLARNCFQAYPVGGPSQFTTVYSLNMEHNHIGKIPFGIFSRAKALSKLNMKDNQLTSLPLDIGTWKSMVELNLATNQLTKIPDDISELTSLEILVLSNNLLRKLPHGLGNLRKLRELDLEENKLESLPNEIAYL-KDLQKLVLTNNQLTSLPRGIGHLCSLTHLMVGENQLTHVPEEIGTLENLE 469 HSP 2 Score: 51.2174 bits (121), Expect = 9.982e-7 Identity = 95/431 (22.04%), Postives = 189/431 (43.85%), Query Frame = 3
Query: 282 THLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSI---NLRHLGEKIDSNMESL---LQSGQILSDHISNTIFDLPAVQAVEMEFCKINYFKSFQSKA--LLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXT--TLYLQGNQIEKITKSLF-QMKSLKVLDLSHNKIKKLTISLDYYNK----------------------SLETLKXXXXXXXXXXXXXXYLEKLENLDVSSNNISELPLDLCLMKNIK----TAHYFNGLHR-IG-------LWVSSNPIEFPPKCVWNTTNIDVIY 1439
T L++++ +I SLP +I +L L L + N C LP + L L L ++E +L +P T+ +TSL LD+ N + + + L L L + + + ++I KL L + N I+ +P + ++ SL TL + L HL E+I + ++ LQ ++L + ++I +L ++ + + + +++ + + L +L++ N +PE +L+ + T +L ++ N I KI +F + K+L L++ N++ L + + + SLE L +++N ++ +P+ + L KL LD+ N + LP ++ +K+++ T + L R IG L V N + P+ + N++ +Y
Sbjct: 52 TRLDLAKRSIASLPPNIKELTQLTELYLYGNRLPC--------LPTEIGCLVNLVTLALNENSLTGLPDTLTGLTSLRMLDLRHNKLRSIPPVVYRLTSLTVLYLRFNRITQVEKDIGNLSKLTMLSVRENKIKLLPAEIGELRSLLTLDVAHNQLEHLPEEIGNCVQVTNLDLQHNELLD--LPDSIGNLASLNRLGLRYNRLSAVPTTLANCTELEDLNLENNNISTLPEGLLSSLVNLSSLTLARNCFQAYPVGGPSQFTTVYSLNMEHNHIGKIPFGIFSRAKALSKLNMKDNQLTSLPLDIGTWKSMVELNLATNQLTKIPDDISELTSLEILVLSNNLLRKLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLTSLPRGIGHLCSLTHLMVGENQLTHVPEEIGTLENLEELY 472
BLAST of Roc domain-containing protein vs. Ensembl Sea Lamprey
Match: LRRC2 (leucine rich repeat containing 2 [Source:HGNC Symbol;Acc:HGNC:14676]) HSP 1 Score: 68.9366 bits (167), Expect = 1.629e-12 Identity = 59/190 (31.05%), Postives = 103/190 (54.21%), Query Frame = 3
Query: 195 NNED--DFKSINLSNTALTVVP--VTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECN-LVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHL 749
+NED D + + N+ L V+P V F+R++ L++S+N ++ LP +I L L+ L +S N +P+ + + + L+ L++S N L +P + + L LD+S N + + + LQWL+ L LPQ+I E++ET+LL+ N I+ +P L+D+G L+TL ++ HL
Sbjct: 116 SNEDMVDLNELRVLNSRLHVLPRFVANFQRLQT--LDLSKNCLQELPKEIGLLKGLQQLLLSYNQLRR--------IPEELGDCESLERLDLSSNNSLEELPYQLSSLKKLVLLDLSVNKFSSVPIAVLRMSGLQWLDMSKNRLHELPQDIDRLERVETMLLHHNSIRYLPLALSDMGELRTLVVSADHL 295
BLAST of Roc domain-containing protein vs. Ensembl Sea Lamprey
Match: scrib (scribble planar cell polarity protein [Source:NCBI gene;Acc:368473]) HSP 1 Score: 68.5514 bits (166), Expect = 5.445e-12 Identity = 48/170 (28.24%), Postives = 89/170 (52.35%), Query Frame = 3
Query: 219 INLSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTL 728
+++S L +P + +T S+N+++ LP ++ L +L +L +N +T LP+++ + + L L ++E LV +PA+I ++T L L++ KN + + +IG L L+ + L +P EI G ++ L L GN ++ +P LA + SLK L
Sbjct: 172 LDISQNRLERLPDAIGGLAALTDFLASQNHLEELPEELGKLKHLSILKADQN--------RLTHLPEAIGDCENLTELILTENQLVTLPASIGKLTKLTNLNLDKNRLNSIPPEIGGCGALNVLSLRDNRLTQVPGEISGASQIHVLDLAGNRLENLPIELAKL-SLKAL 332 HSP 2 Score: 65.0846 bits (157), Expect = 6.211e-11 Identity = 94/350 (26.86%), Postives = 169/350 (48.29%), Query Frame = 3
Query: 264 FKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDSNMESLLQSGQILSDHISNTIFDLP-AVQAVEMEFCKINYFKSFQSKALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISLDYYNKSLETLKXXXXXXXXXXXXXXYLEKLENLDVSSNNISELPLDLC 1310
F+ + L +S+N ++ LP DI++ ++L L++SRN D+ +P S+K CL+ ++ S L +P ++ SL L ++ ++ L DIGNL L L + LKTLP + KLE L L N ++T+P L + +++ L ++ L E + S + L + + D N + LP A+ + AL + S N +E+PE + L +L IL +N L ++ + + ENLT L L NQ+ + S+ ++ L L+L N++ + + +L L + N + +P +I ++ LD++ N + LP++L
Sbjct: 3 FRLHNLRKLGLSDNELQRLPPDIANFMHLVDLDMSRN--------DIAEIPDSIKLCTCLEVVDFSGNPLTRLPEGFTQLKSLIYLSLNDVSLQGLPDDIGNLSNLVTLELRENLLKTLPTSLHLLVKLEQLDLGNNELETLPGSLGSLPNVRELWLDGNQL-EALPSEIGELRR--LVCLDISQNRLERLPDAIGGL---------------AALTDFLASQNHLEELPEELGKLKHLSILKADQNRLTHLPEAIGDCENLTELILTENQLVTLPASIGKLTKLTNLNLDKNRLNSIPPEIGGCG-ALNVLSLRDNRLTQVPGEISGASQIHVLDLAGNRLENLPIELA 325 HSP 3 Score: 64.6994 bits (156), Expect = 9.750e-11 Identity = 49/172 (28.49%), Postives = 82/172 (47.67%), Query Frame = 3
Query: 216 SINLSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLS 731
++ L L +P +L +++ L++ N +++LP + L N+ L + N + LP + L+ L L+IS+ L +P I + +L S+N++ EL ++G L L L A L LP+ I CE L L+L N + T+P A IG L L+
Sbjct: 102 TLELRENLLKTLPTSLHLLVKLEQLDLGNNELETLPGSLGSLPNVRELWLDGN--------QLEALPSEIGELRRLVCLDISQNRLERLPDAIGGLAALTDFLASQNHLEELPEELGKLKHLSILKADQNRLTHLPEAIGDCENLTELILTENQLVTLP---ASIGKLTKLT 262
BLAST of Roc domain-containing protein vs. Ensembl Sea Lamprey
Match: lrch3 (leucine-rich repeats and calponin homology (CH) domain containing 3 [Source:ZFIN;Acc:ZDB-GENE-071004-44]) HSP 1 Score: 64.6994 bits (156), Expect = 2.914e-11 Identity = 47/138 (34.06%), Postives = 73/138 (52.90%), Query Frame = 3
Query: 219 INLSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEI 632
+N+S LT +P L K + + LN S N + SLP ++ L L L++S N ++ LP + +L CL+ LN+ NLV +P I ++ L QLD+S N +GE+ L QLQ L + +K+ P +I
Sbjct: 49 LNISRNQLTTLPPYLCK-LPLQVLNASNNKLVSLPEELGQLKELSALDVSCN--------EIQALPPQVASLTCLRDLNVRRNNLVILPDEIADLP-LVQLDVSCNRLGEIPVSFRKLKQLQSLVLDNNPMKSPPAQI 176 HSP 2 Score: 55.8398 bits (133), Expect = 1.954e-8 Identity = 46/138 (33.33%), Postives = 68/138 (49.28%), Query Frame = 3
Query: 222 NLSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIV 635
+LS L VP+ + + + L + N I+S+P I +L +L LNISRN +T LP + L L+ LN S LV +P + ++ L LD+S N I L + +L L+ LN + L LP EI
Sbjct: 4 DLSKNRLNEVPLEVCHFVSLESLVLYHNCIRSIPEAIVNLRSLTYLNISRN--------QLTTLPPYLCKLP-LQVLNASNNKLVSLPEELGQLKELSALDVSCNEIQALPPQVASLTCLRDLNVRRNNLVILPDEIA 132
BLAST of Roc domain-containing protein vs. Ensembl Sea Lamprey
Match: lrrc40 (leucine rich repeat containing 40 [Source:NCBI gene;Acc:334130]) HSP 1 Score: 63.5438 bits (153), Expect = 1.798e-10 Identity = 48/156 (30.77%), Postives = 77/156 (49.36%), Query Frame = 3
Query: 279 ITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRH 746
+T L+V +N + LP + +LVNL+ LN+S N LP+S+ + L L++ L I I + L +LD+S N + L +G L ++ LN L+ LP EI + L L N+++++P L + SL+ L LRH
Sbjct: 109 LTVLDVHDNQLTELPQVLGELVNLQKLNVSHNKLQT--------LPESLWAISSLLSLHVEHNELEGISNNIGNLARLEELDLSSNRLTALPGTLGKLTRVTKLNVAENKLRELPTEIKSMKGLCQLEATHNLLESVPAALGGMASLQQLY--LRH 254
BLAST of Roc domain-containing protein vs. Ensembl Yeast
Match: CYR1 (Adenylate cyclase; required for cAMP production and cAMP-dependent protein kinase signaling; the cAMP pathway controls a variety of cellular processes, including metabolism, cell cycle, stress response, stationary phase, and sporulation [Source:SGD;Acc:S000003542]) HSP 1 Score: 56.9954 bits (136), Expect = 1.481e-8 Identity = 90/315 (28.57%), Postives = 144/315 (45.71%), Query Frame = 3
Query: 216 SINLSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDSNMESLLQSGQILSD-HISNTIFDLPAVQAVEMEFCKINY--FKSFQSKALLELHISGNFFQEIP-ETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIK 1148
S+ + N + P + K ++ L + N I+ +P I L NL +LN+ C +++ LP LK L+ L++S + P I T+L Q+D+S N I L L +L +N H L + ++ L TL L N I +I KT + NL++L L+D ISN LP ++A+E++ I FK F K + L ++ IP E + L+ L+ L+L++N L + ++ KL L L + N++E I L Q+KSL+ LDL N I+
Sbjct: 844 SLRMVNIRASKFPSNITKAYKLVSLELQRNFIRKVPNSIMKLSNLTILNL-----QC---NELESLPAGFVELKNLQLLDLSSNKFMHYPEVINYCTNLLQIDLSYNKIQSLPQSTKYLVKLAKMNLSHNKLNFI-GDLSEMTDLRTLNLRYNRISSI----------KTNASNLQNL----------------FLTDNRISNFEDTLPKLRALEIQENPITSISFKDFYPKNMTSLTLNKAQLSSIPGELLTKLSFLEKLELNQNNLTRLPQEISKLTKLVFLSVARNKLEYIPPELSQLKSLRTLDLHSNNIR 1123
BLAST of Roc domain-containing protein vs. Ensembl Yeast
Match: CCR4 (Component of the CCR4-NOT transcriptional complex; CCR4-NOT is involved in regulation of gene expression; component of the major cytoplasmic deadenylase, which is involved in mRNA poly(A) tail shortening [Source:SGD;Acc:S000000019]) HSP 1 Score: 50.0618 bits (118), Expect = 1.638e-6 Identity = 30/110 (27.27%), Postives = 62/110 (56.36%), Query Frame = 3
Query: 408 ILPKSMK-NLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSI 734
++PK K + + L++S + I A I++ L +L ++ N++ EL ++I NL L+ L+ H L +LP E+ C +L+ + N++ T+P+ ++ +L+ L +
Sbjct: 324 VMPKDSKYDDQLWHALDLSNLQIFNISANIFKYDFLTRLYLNGNSLTELPAEIKNLSNLRVLDLSHNRLTSLPAELGSCFQLKYFYFFDNMVTTLPWEFGNLCNLQFLGV 433
BLAST of Roc domain-containing protein vs. Ensembl Nematostella
Match: EDO37227 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SGD7]) HSP 1 Score: 89.3521 bits (220), Expect = 6.365e-20 Identity = 56/164 (34.15%), Postives = 93/164 (56.71%), Query Frame = 3
Query: 240 LTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLS 731
L V+PV+ ++ + + N + SLP +IS L +L+ L + N ++T LP+ + ++KCL+ LN+S L +P TI ++ L L I+ N + L ++G+L QLQ L+ + L LP ++ C +LETLL GN+++ +P L D+ LK LS
Sbjct: 27 LNVLPVSFLHLKKVQRVYLKYNLLTSLPQEISRLSSLKELYLHSN--------NLTHLPQEIGHIKCLESLNVSHNFLQNLPPTIGQLQHLQYLHIANNQLHSLPREVGHLKQLQVLDIMNNNLHQLPWQLSDCVRLETLLFDGNLVEWLPQQLTDLKGLKELS 182 HSP 2 Score: 47.3654 bits (111), Expect = 9.516e-6 Identity = 32/111 (28.83%), Postives = 59/111 (53.15%), Query Frame = 3
Query: 402 MTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSI 734
+ +LP S +LK ++ + + L +P I ++SL +L + NN+ L +IG++ L+ LN H L+ LP I + L+ L + N + ++P ++G LK L +
Sbjct: 27 LNVLPVSFLHLKKVQRVYLKYNLLTSLPQEISRLSSLKELYLHSNNLTHLPQEIGHIKCLESLNVSHNFLQNLPPTIGQLQHLQYLHIANNQLHSLP---REVGHLKQLQV 134
BLAST of Roc domain-containing protein vs. Ensembl Nematostella
Match: EDO46974 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RNR2]) HSP 1 Score: 86.2705 bits (212), Expect = 1.054e-17 Identity = 89/329 (27.05%), Postives = 158/329 (48.02%), Query Frame = 3
Query: 207 DFKSINLSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDSNMESLLQSGQILSDHISNTIFDLPAVQAVEMEFCKINYFKSFQSKALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISLDYYNKSLET 1193
+ + I+ S + +P T +THL +++ + LP + L++L +L + N + +LPKSM LK L+ L+I +P + + +L +L + N I ELR +IG L +L +L+ L+ LP EI + L L L N++ IP + +G L+TL + HLGE + +++ L++ +++ N + LP + Y + + L+I NF + IP + + + IL L N L+++ D + ++ L + L N++E + S ++ SLK L LS N+ K + YN S T
Sbjct: 95 NLQEIDASVNPIGKIPETFCHLANLTHLYLNDAFLDFLPGNFGRLISLRILELREN--------HLRVLPKSMSQLKNLERLDIGNNEFTELPMVVGCLLNLTELWMDSNAIKELRPEIGLLRRLMFLDVSKNRLEWLPPEIESLQSLTDLYLSNNLLIEIPEQIGALGKLQTLKLEENHLGE-LPNSIGKLVELEELIL--TCNELVSLPP---------SLGYLRKLRV-----LNIDENFLESIPSELGSCTAMTILSLRDNRLVHLPDSIGRMPKLQVINLASNRLEYLPYSFHKLVSLKALWLSENQSKPMIPLQSDYNTSTNT 398
BLAST of Roc domain-containing protein vs. Ensembl Nematostella
Match: EDO37499 (Leucine-rich repeat protein soc-2 homolog [Source:UniProtKB/Swiss-Prot;Acc:A7SFP1]) HSP 1 Score: 87.0409 bits (214), Expect = 1.514e-17 Identity = 64/176 (36.36%), Postives = 92/176 (52.27%), Query Frame = 3
Query: 210 FKSINLSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNV-IQTIPYLLADIGSLKTLSI 734
+N+ + LT +P+ I + LNV+ N I LP DI LVNLEVL +S N + LP+ + L+ L+ L+I E L IP I + SL +L + N +G L IG L + +L+ L ++PQEI E LE L L N +Q++PY L GSL+ +SI
Sbjct: 367 LSKLNVKDNQLTSLPLDFGSWISLVELNVATNQISKLPEDIQWLVNLEVLILSNN--------LLKKLPRGIGALRKLRVLDIEENKLESIPTEIEYLRSLERLVLQSNCLGSLPRSIGYLSSVTYLSVGENELVSVPQEIGNMESLEQLYLNDNENLQSLPYELVLCGSLQIMSI 534 HSP 2 Score: 82.0333 bits (201), Expect = 4.483e-16 Identity = 108/466 (23.18%), Postives = 197/466 (42.27%), Query Frame = 3
Query: 177 NRDARKNNEDDFKSINLSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPK---------------------------------------SMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSI---NLRHLGEKIDSNMESLLQSGQILSDHISNTIFDL-PAVQAVEMEFCKINYF-----------------KSFQSK-------------------ALLELHISGNFFQEIPETV---LNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISLDYYNKSLETLKXXXXXXXXXXXXXXYLEKLENLDVSSNNISELPLDLCLMKNIK 1328
+++ +K E+ ++LS A+TV+P L + + L + N I LP ++ L NLE L +S N T PD++ L K + NLK L+ L++ E + +P I ++ L LDIS N+I L ++IGN + L+ QH + +LP I + L L N + ++P LA+ + +I N+ L EK+ S++++L S +S F++ PA +FC++N F + SK +L+EL+++ N ++PE + +NL L L N ++K+ + + ++ L+VLD+ NK++ + ++Y +SLE L + N + ++P I YL + L V N + +P ++ M++++
Sbjct: 77 HKEIQKCREEGATRLDLSKAAVTVLPKELKELTSLRELYLYGNRIAVLPPEVGLLPNLETLALSENNL-TTLPDNLVKLTKLKVLDLRHNKIKEIPDVIYKLTTLTTLYLRFNRISVVESGIGNLKLLERLSLRENKIKILPRVIGQLVHLVTLDISHNHIENLPAEIGNCVHMTSLDLQHNDIPSLPDSIGRLTAMTRLGLRYNQLSSLPDSLANCSGIDEFNIEGNNIAELPEKLLSSLKNL------TSLTLSRNKFEVFPA--GPPKQFCQVNTFIMEHNRMQKIPFGVFNKAKYLSKLNVKDNQLTSLPLDFGSWISLVELNVATNQISKLPEDIQWLVNLE--------------------------VLILSNNLLKKLPRGIGALRKLRVLDIEENKLESIPTEIEYL-RSLERLVLQSNCLGSLPRSIGYLSSVTYLSVGENELVSVPQEIGNMESLE 506
BLAST of Roc domain-containing protein vs. Ensembl Nematostella
Match: EDO35138 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SMB5]) HSP 1 Score: 66.2402 bits (160), Expect = 8.260e-12 Identity = 49/167 (29.34%), Postives = 77/167 (46.11%), Query Frame = 3
Query: 219 INLSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSP---------------DDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGN 674
+NL N +T +P +L + +LN+ N +K P ++S L L VL+++ N + + +LP + CL YL++ +LV P I ++TSL L +S N+I EL I L L+ L ++ LP I EKL+ L L N
Sbjct: 88 LNLQNNQITNLPSSLADMNGLCYLNLEANELKIFPEEVSQLSRLRVLHLNSNNLRALPESFKLLNHLRILYLKDNKLRVLPDWFASFHCLAYLSMENNDLVCFPGEISKLTSLEVLILSGNSIRELPDSIKELVNLKELFLGRNKIRKLPPSITKLEKLQVLYLQEN 254 HSP 2 Score: 61.2326 bits (147), Expect = 3.875e-10 Identity = 56/213 (26.29%), Postives = 91/213 (42.72%), Query Frame = 3
Query: 207 DFKSINLSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSP----------------DDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQ--------------WLNAQHC---------GLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTL 728
+ +NLS +T P F +T L + + ++ LPA + LV LEVL+++ N F T P + +T LP S+ ++ L YLN+ L P + +++ L L ++ NN+ L L+ L+ W + HC L P EI LE L+L GN I+ +P + ++ +LK L
Sbjct: 15 QLQVLNLSGNHITNFPYRFFMLRFLTELYLRNDFLEFLPAQVCTLVQLEVLDLA-NNFIRTLPYSSGHLTRLRWLNLQNNQITNLPSSLADMNGLCYLNLEANELKIFPEEVSQLSRLRVLHLNSNNLRALPESFKLLNHLRILYLKDNKLRVLPDWFASFHCLAYLSMENNDLVCFPGEISKLTSLEVLILSGNSIRELPDSIKELVNLKEL 226 HSP 3 Score: 59.3066 bits (142), Expect = 1.373e-9 Identity = 76/292 (26.03%), Postives = 129/292 (44.18%), Query Frame = 3
Query: 309 IKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDSNMESLLQSGQILSDHIS------NTIFDLP-------AVQAVEMEFCKINYFKSFQSK--ALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHN 1139
++ P I +L L+VLN+S G H T+ P L+ L L + L F+PA + + L LD++ N I L G+L +L+WLN Q+ + LP + L L L N ++ P ++ + L+ L +N +N+ +L +S ++L +H+ N + LP + + ME + F SK +L L +SGN +E+P+++ L NL L+L N+I K+ S+ +++ L+VL L N
Sbjct: 3 LQYFPEQILELTQLQVLNLS--GNHITN------FPYRFFMLRFLTELYLRNDFLEFLPAQVCTLVQLEVLDLANNFIRTLPYSSGHLTRLRWLNLQNNQITNLPSSLADMNGLCYLNLEANELKIFPEEVSQLSRLRVLHLN--------SNNLRALPESFKLL-NHLRILYLKDNKLRVLPDWFASFHCLAYLSMENNDLVCFPGEISKLTSLEVLILSGNSIRELPDSIKEL-----------------------VNLKELFLGRNKIRKLPPSITKLEKLQVLYLQEN 254
BLAST of Roc domain-containing protein vs. Ensembl Nematostella
Match: EDO33432 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SS78]) HSP 1 Score: 67.781 bits (164), Expect = 1.739e-11 Identity = 133/510 (26.08%), Postives = 226/510 (44.31%), Query Frame = 3
Query: 261 LFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSIN---LRHLGEKIDSNMESLLQSGQILSDHISNTIFDLPAVQAVEMEFCKINYFKSFQSKALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISLDYYNKSLETLKXXXXXXXXXXXXXXYLEKLENLDVSSNNISELPLDLCLMKNIKTAHYFNGLHRIGLWVSSNPIEFPPKCVWNT-----TNIDVIYSFLQKTKIKRLQIKSPIRVVLIGDNSIKDNFLERFLGKRISND--SEYLTINQWTSENSVPFVLVNVNCHPTYVMH------IRHYMEDNAFIWIFIDHFKTKNLLKES 1742
F+ I L +S+N I LP ++ +L NL+ +ISRN D+ +P+++K K L L++S + +P ++ L L ++ ++ L DIG+L +L L A+ +K LP + KLE L L N ++ +P ++ + SL ++ L+ L +I N++ L QI D N I LP E+ FC +L +LH+S N +E+P+T+ L LQ+L + +N L+ + + L L L N ++ + ++ ++ L +L++ N+++ L + L K L + N ++ +P +I L LDVS N + LPL + + +K LW+S N + P T TN V+ FL + G S+ N E++L RI N S+ TIN E+ + F + HP H HY++D + K K LL ++
Sbjct: 2 FFRLYNIRRLGLSDNEIARLPPEVGNLANLQEFDISRN--------DICDIPENIKYCKSLVSLDLSGNPISKLPDGFSQLQHLTTLCLNDVSLIRLPPDIGSLTELTVLEARENLIKFLPVSLAFLSKLERLDLGCNELEELPDVVGSLPSLAEFWLDGNLLKTLPTEI-GNLKKL----QIF-DVSENKIEYLPD----EICFC----------GSLTDLHLSQNLLEELPDTIGKLKKLQLLKVDQNRLITLTPAIGGCIALQELILTENLLDVLPSTMGKLHKLSLLNVDRNRLEVLPVELGSCTK-LSVFSLRDNLLQRLPTEIGNCRNLHVLDVSGNRLECLPLTIGTLP-LKA-----------LWLSEN--QSQPVLKLQTEEDEKTNSKVLTCFLLPQQ---------------GMGSLV-NLSEKYLSGRIHNKTRSKGKTINAEWREHMIRF---EGDDHPERQDHRLRRRDTPHYLKDKRIQLKGDEEVKVKELLAKA 449 HSP 2 Score: 52.7582 bits (125), Expect = 7.481e-7 Identity = 56/191 (29.32%), Postives = 88/191 (46.07%), Query Frame = 3
Query: 225 LSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDD----------------MTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHL 749
L++ +L +P + E+T L EN IK LP ++ L LE L++ N PD + LP + NLK L+ ++SE + ++P I SL L +S+N + EL IG L +LQ L L TL I GC L+ L+L N++ +P + + L L+++ L
Sbjct: 82 LNDVSLIRLPPDIGSLTELTVLEARENLIKFLPVSLAFLSKLERLDLGCNELE-ELPDVVGSLPSLAEFWLDGNLLKTLPTEIGNLKKLQIFDVSENKIEYLPDEICFCGSLTDLHLSQNLLEELPDTIGKLKKLQLLKVDQNRLITLTPAIGGCIALQELILTENLLDVLPSTMGKLHKLSLLNVDRNRL 271
BLAST of Roc domain-containing protein vs. Ensembl Medaka
Match: mfhas1 (malignant fibrous histiocytoma amplified sequence 1 [Source:NCBI gene;Acc:101173528]) HSP 1 Score: 82.0333 bits (201), Expect = 2.402e-15 Identity = 115/508 (22.64%), Postives = 207/508 (40.75%), Query Frame = 3
Query: 276 EITHLNVSENNIKSLPADISDLVN-LEVLNISRNGFHCT---------------SPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTL---SINLRHLGEKID--SNMESLLQSGQILSDHISNTIFDLPAVQAVEMEFCKINYFKSFQSKALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISLDYYNKSLETLKXXXXXXXXXXXXXXYLEKLENLDVSSNNISELPLDLCLMKNIKTAHYFNGLHRIGLW-VSSNPIEFPPKCVWNTTNIDVIYSFLQKTKIKRLQIKSPIRVVLIGDNSIKDNFLER-FLGKRI-SNDSEYLTINQWTSE--NSVPFVLVNVNCHPTYVMHIRHYMEDNAFIWIFIDHFKT 1721
E+ LN+ N+++ LP ++ +N L VL + RN F S + + L + + L+ LK L +S + +PA I + +L +LDIS N + L +L +L+ L+A H L P EI+ +LE L L GN +P + + S+K L S+ + L E N+ESL+ G LS A+ F + K +++S N Q P+ +L + L LYL N++ + + + Q+ L L L +N I +L S+ + LE LE L + N+I+ LP + F L R+ +W V NP+ PP V I I + Q+ +L +K +++VL+G L R +G R + + + W ++ + F++ +++ +P + + ++ + +++ + + K+
Sbjct: 62 EVEALNLGNNSLQELPEELGSSLNKLRVLELRRNKFTAAPRVLCELGQLVELDMSHNCLRTLSEGLGQLRALKKLCVSHNKIQSLPAQIGALQALEELDISFNLLHGLPRSFSSLTRLRALDADHNQLSQFPVEILALGQLEELDLSGNRFVALPANIWRLTSIKVLWLSSLRMASLPETFCRLQNLESLMLDGNRLS--------------ALPPSFGLLQRLKM--------MNLSSNQLQVFPQALLGV-----------------------CGLEELYLSRNRLSHVPEEISQLGRLVNLWLDNNSITRLPDSI------------------------VDLENLEELVLQGNHIAVLPDN------------FGKLSRVNIWKVKDNPLIQPPYEVC-MKGIPYIALYQQELAQSQLAVKPRLKLVLMGRKDAGKTLLRRSLMGTREDGGGNRGVELVHWEADAHRKLTFMVFDLSGNPNFDL-VKPFFLSPGALYVLVVNLKS 486 HSP 2 Score: 61.2326 bits (147), Expect = 6.027e-9 Identity = 46/162 (28.40%), Postives = 74/162 (45.68%), Query Frame = 3
Query: 207 DFKSINLSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIP 692
+ ++LS +P +++ I L +S + SLP L NLE L + N ++ LP S L+ LK +N+S L P + + L +L +S+N + + +I L +L L + + LP IV E LE L+L GN I +P
Sbjct: 201 QLEELDLSGNRFVALPANIWRLTSIKVLWLSSLRMASLPETFCRLQNLESLMLDGN--------RLSALPPSFGLLQRLKMMNLSSNQLQVFPQALLGVCGLEELYLSRNRLSHVPEEISQLGRLVNLWLDNNSITRLPDSIVDLENLEELVLQGNHIAVLP 354
BLAST of Roc domain-containing protein vs. Ensembl Medaka
Match: erbin (erbb2 interacting protein [Source:NCBI gene;Acc:101172095]) HSP 1 Score: 80.1073 bits (196), Expect = 8.078e-15 Identity = 75/285 (26.32%), Postives = 129/285 (45.26%), Query Frame = 3
Query: 318 LPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDSNMESLLQSGQILSDHISNTIFDLPAVQAVEMEFCKINYFKS--FQSKALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISL 1166
LPA L L++L + N + LPKSM+ L L+ L++ +P + ++ + +L + N + L + +G L L++L+ L+ + ++I GCE L+ LLL N + +P A IGSLK L+ K+D N Q++ + +++ L A+ ++ F +I S Q A+ NF E+P + N NLT L+L N++E + + + M+ LKV++LS+NK+K L S
Sbjct: 152 LPASFGRLAKLQILELREN--------QLQNLPKSMQKLTQLERLDLGSNEFTEVPEVLEHLSGIKELWMDGNKLTVLPAMVGKLKNLEYLDMSKNNLEMVDEQISGCENLQDLLLSNNALTQLP---ASIGSLKKLT------ALKVDEN--------QLM--FLPDSVGGLTAIDELDCSFNEIEALPSSIGQWVAIRTFAADHNFLTELPPEMGNWK-----------------------NLTVLFLHSNKLESLPEEMGDMQKLKVINLSNNKLKNLPYSF 386 HSP 2 Score: 78.1814 bits (191), Expect = 3.544e-14 Identity = 53/175 (30.29%), Postives = 94/175 (53.71%), Query Frame = 3
Query: 213 KSINLSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSIN 737
K + + LTV+P + K + +L++S+NN++ + IS NL+ L +S N +T LP S+ +LK L L + E L+F+P ++ +T++ +LD S N I L S IG ++ A H L LP E+ + L L L+ N ++++P + D+ LK ++++
Sbjct: 209 KELWMDGNKLTVLPAMVGKLKNLEYLDMSKNNLEMVDEQISGCENLQDLLLSNNA--------LTQLPASIGSLKKLTALKVDENQLMFLPDSVGGLTAIDELDCSFNEIEALPSSIGQWVAIRTFAADHNFLTELPPEMGNWKNLTVLFLHSNKLESLPEEMGDMQKLKVINLS 375
BLAST of Roc domain-containing protein vs. Ensembl Medaka
Match: lrch4 (leucine-rich repeat and calponin homology domain-containing protein 4 [Source:NCBI gene;Acc:101159618]) HSP 1 Score: 76.6406 bits (187), Expect = 9.266e-15 Identity = 71/251 (28.29%), Postives = 117/251 (46.61%), Query Frame = 3
Query: 144 INMDERSLENENRDARKNNEDDFKSINLSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEI---------VGCEK-------------LETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDSNMESLLQSGQILSDHISNTIF 830
+N+ R L+ R AR + D +LS L +P L I + L++ N ++SL +++ +L L LN+SRN ++ LP S+ L L+ L +S L +P++++ +T L QLD+S N + L +++ L+ L+ LN + L TLP+EI V C + L+ LLL N +QT P + G H+ + + NME+ +S L H+ T F
Sbjct: 51 LNLSNRKLKEFPRTARNYDLSDITHADLSKNRLCELPEELCHFISLETLSLYHNGMRSLSSNLGNLQALTYLNLSRN--------LLSSLPPSVFQLSLLRVLILSNNKLTSLPSSVFSLTQLRQLDVSCNELQSLPAELCQLECLRDLNLRRNRLTTLPEEISELPLVRLDVSCNRITNVPLCYRHLRHLQVLLLDNNPLQTPPAQVCSKGKY--------HIFKYL--NMEACKRSQSELEKHLRPTGF 283 HSP 2 Score: 72.0182 bits (175), Expect = 3.709e-13 Identity = 51/167 (30.54%), Postives = 91/167 (54.49%), Query Frame = 3
Query: 216 SINLSNTALTVVPVTL--FKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADI 710
++NLSN L P T + +ITH ++S+N + LP ++ ++LE L++ NG M L ++ NL+ L YLN+S L +P ++++++ L L +S N + L S + +L QL+ L+ L++LP E+ E L L L N + T+P ++++
Sbjct: 50 ALNLSNRKLKEFPRTARNYDLSDITHADLSKNRLCELPEELCHFISLETLSLYHNG--------MRSLSSNLGNLQALTYLNLSRNLLSSLPPSVFQLSLLRVLILSNNKLTSLPSSVFSLTQLRQLDVSCNELQSLPAELCQLECLRDLNLRRNRLTTLPEEISEL 208
BLAST of Roc domain-containing protein vs. Ensembl Medaka
Match: erbin (erbb2 interacting protein [Source:NCBI gene;Acc:101172095]) HSP 1 Score: 79.7221 bits (195), Expect = 1.158e-14 Identity = 75/285 (26.32%), Postives = 129/285 (45.26%), Query Frame = 3
Query: 318 LPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDSNMESLLQSGQILSDHISNTIFDLPAVQAVEMEFCKINYFKS--FQSKALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISL 1166
LPA L L++L + N + LPKSM+ L L+ L++ +P + ++ + +L + N + L + +G L L++L+ L+ + ++I GCE L+ LLL N + +P A IGSLK L+ K+D N Q++ + +++ L A+ ++ F +I S Q A+ NF E+P + N NLT L+L N++E + + + M+ LKV++LS+NK+K L S
Sbjct: 152 LPASFGRLAKLQILELREN--------QLQNLPKSMQKLTQLERLDLGSNEFTEVPEVLEHLSGIKELWMDGNKLTVLPAMVGKLKNLEYLDMSKNNLEMVDEQISGCENLQDLLLSNNALTQLP---ASIGSLKKLT------ALKVDEN--------QLM--FLPDSVGGLTAIDELDCSFNEIEALPSSIGQWVAIRTFAADHNFLTELPPEMGNWK-----------------------NLTVLFLHSNKLESLPEEMGDMQKLKVINLSNNKLKNLPYSF 386 HSP 2 Score: 77.7962 bits (190), Expect = 5.029e-14 Identity = 53/175 (30.29%), Postives = 94/175 (53.71%), Query Frame = 3
Query: 213 KSINLSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSIN 737
K + + LTV+P + K + +L++S+NN++ + IS NL+ L +S N +T LP S+ +LK L L + E L+F+P ++ +T++ +LD S N I L S IG ++ A H L LP E+ + L L L+ N ++++P + D+ LK ++++
Sbjct: 209 KELWMDGNKLTVLPAMVGKLKNLEYLDMSKNNLEMVDEQISGCENLQDLLLSNNA--------LTQLPASIGSLKKLTALKVDENQLMFLPDSVGGLTAIDELDCSFNEIEALPSSIGQWVAIRTFAADHNFLTELPPEMGNWKNLTVLFLHSNKLESLPEEMGDMQKLKVINLS 375
BLAST of Roc domain-containing protein vs. Ensembl Medaka
Match: erbin (erbb2 interacting protein [Source:NCBI gene;Acc:101172095]) HSP 1 Score: 79.7221 bits (195), Expect = 1.158e-14 Identity = 75/285 (26.32%), Postives = 129/285 (45.26%), Query Frame = 3
Query: 318 LPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDSNMESLLQSGQILSDHISNTIFDLPAVQAVEMEFCKINYFKS--FQSKALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISL 1166
LPA L L++L + N + LPKSM+ L L+ L++ +P + ++ + +L + N + L + +G L L++L+ L+ + ++I GCE L+ LLL N + +P A IGSLK L+ K+D N Q++ + +++ L A+ ++ F +I S Q A+ NF E+P + N NLT L+L N++E + + + M+ LKV++LS+NK+K L S
Sbjct: 152 LPASFGRLAKLQILELREN--------QLQNLPKSMQKLTQLERLDLGSNEFTEVPEVLEHLSGIKELWMDGNKLTVLPAMVGKLKNLEYLDMSKNNLEMVDEQISGCENLQDLLLSNNALTQLP---ASIGSLKKLT------ALKVDEN--------QLM--FLPDSVGGLTAIDELDCSFNEIEALPSSIGQWVAIRTFAADHNFLTELPPEMGNWK-----------------------NLTVLFLHSNKLESLPEEMGDMQKLKVINLSNNKLKNLPYSF 386 HSP 2 Score: 77.7962 bits (190), Expect = 5.029e-14 Identity = 53/175 (30.29%), Postives = 94/175 (53.71%), Query Frame = 3
Query: 213 KSINLSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSIN 737
K + + LTV+P + K + +L++S+NN++ + IS NL+ L +S N +T LP S+ +LK L L + E L+F+P ++ +T++ +LD S N I L S IG ++ A H L LP E+ + L L L+ N ++++P + D+ LK ++++
Sbjct: 209 KELWMDGNKLTVLPAMVGKLKNLEYLDMSKNNLEMVDEQISGCENLQDLLLSNNA--------LTQLPASIGSLKKLTALKVDENQLMFLPDSVGGLTAIDELDCSFNEIEALPSSIGQWVAIRTFAADHNFLTELPPEMGNWKNLTVLFLHSNKLESLPEEMGDMQKLKVINLS 375
BLAST of Roc domain-containing protein vs. Planmine SMEST
Match: SMESG000038728.1 (SMESG000038728.1) HSP 1 Score: 1772.29 bits (4589), Expect = 0.000e+0 Identity = 926/942 (98.30%), Postives = 926/942 (98.30%), Query Frame = 3
Query: 150 MDERSLENENRDARKNNEDDFKSINLSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDSNMESLLQSGQILSDHISNTIFDLPAVQAVEMEFCKINYFKSFQSKALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISLDYYNKSLETLKXXXXXXXXXXXXXXYLEKLENLDVSSNNISELPLDLCLMKNIKTAHYFNGLHRIGLWVSSNPIEFPPKCVWNTTNIDVIYSFLQKTKIKRLQIKSPIRVVLIGDNSIKDNFLERFLGKRISNDSEYLTINQWTSENSVPFVLVNVNCHPTYVMHIRHYMEDNAFIWIFIDHFKTKNLLKESEKWIDLVMEYSTDCVIQIVIVNYFENNSEDIFQNFVNFSDKKLIESLRERFSNEKVNILPNILLISPGESLNAFKDDLEYIAIDKDLFQSDEMFNIFTRETKAIENICKSTKCIYVNLNDLISKIREMFPFPTDSIFSCLKCLHKQGKILWFYKNKKLSNKIYPFISLFNKSIRSLIRLDYEEDLDFAKNPLIKAKGLMNGEKFEQVKKSFLKYGEICYPLYKVLTFEFQELRSVKDFLIDANIAWGVPLSVDLEEDIFQRPFVVLAQFNKEKFDKSCFLDSILKKESANIDYGFTIRSTSLSDHSNLFLNLKCEVNCWAVRRYDWMNAVYLHHNNGDVLLYNELSTDLQMNITAIVRSWSKMNPDPLPCDGDFRKWITDWYHCESDSRKNFHYNFVDHSLKDIEEYVLNL 2975
MDERSLENENRDARKNNEDDFKSINLSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDSNMESLLQSGQILSDHISNTIFDLPAVQAVEMEFCKINYFKSFQSKALLELHISGNFFQEIPETVLNLNNLQILDLSKNLLLNINDDLIKLENLTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISLDYYNKSLETLKINHNNIKNIPNDIIYLEKLENLDVSSNNISELPLDLCLMKNIKTAHYFNGLHRIGLWVSSNPIEFPPKCVWNTTNIDVIYSFLQKTKIKRLQIKSPIRVVLIGDNSIKDNFLERFLGKRISNDSEYLTINQWTSENSVPFVLVNVNCHPTYVMHIRHYMEDNAFIWIFIDHFKTKNLLKESEKWIDLVMEYSTDCVIQIVIVNYFENNSEDIFQNFVNFSDKKLIESLRERFSNEKVNILPNILLISPGESLNAFKDDLEYIAIDKDLFQSDEMFNIFTRETKAIENICKSTKCIYVNLNDLISKIREMFPFPTDSIFSCLKCLHKQGKILWFYKNKKLSNKIYPFISLFNKSIRSLIRLDYEEDLDFAKNPLIKAKGLMNGEKFEQVKKSFLKY ELRSVKDFLIDANIAWGVPLSVDLEEDIFQRPFVVLAQFNKEKFDKSCFLDSILKKESANIDYGFTIRSTSLSDHSNLFLNLKCEVNCWAVRRYDWMNAVYLHHNNGDVLLYNELSTDLQMNITAIVRSWSKMNPDPLPCDGDFRKWITDWYHCESDSRKNFHYNFVDHSLKDIEEYVLNL
Sbjct: 1 MDERSLENENRDARKNNEDDFKSINLSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDSNMESLLQSGQILSDHISNTIFDLPAVQAVEMEFCKINYFKSFQSKALLELHISGNFFQEIPETVLNLNNLQILDLSKNLLLNINDDLIKLENLTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISLDYYNKSLETLKINHNNIKNIPNDIIYLEKLENLDVSSNNISELPLDLCLMKNIKTAHYFNGLHRIGLWVSSNPIEFPPKCVWNTTNIDVIYSFLQKTKIKRLQIKSPIRVVLIGDNSIKDNFLERFLGKRISNDSEYLTINQWTSENSVPFVLVNVNCHPTYVMHIRHYMEDNAFIWIFIDHFKTKNLLKESEKWIDLVMEYSTDCVIQIVIVNYFENNSEDIFQNFVNFSDKKLIESLRERFSNEKVNILPNILLISPGESLNAFKDDLEYIAIDKDLFQSDEMFNIFTRETKAIENICKSTKCIYVNLNDLISKIREMFPFPTDSIFSCLKCLHKQGKILWFYKNKKLSNKIYPFISLFNKSIRSLIRLDYEEDLDFAKNPLIKAKGLMNGEKFEQVKKSFLKY----------------ELRSVKDFLIDANIAWGVPLSVDLEEDIFQRPFVVLAQFNKEKFDKSCFLDSILKKESANIDYGFTIRSTSLSDHSNLFLNLKCEVNCWAVRRYDWMNAVYLHHNNGDVLLYNELSTDLQMNITAIVRSWSKMNPDPLPCDGDFRKWITDWYHCESDSRKNFHYNFVDHSLKDIEEYVLNL 926
BLAST of Roc domain-containing protein vs. Planmine SMEST
Match: SMESG000038728.1 (SMESG000038728.1) HSP 1 Score: 779.63 bits (2012), Expect = 0.000e+0 Identity = 434/434 (100.00%), Postives = 434/434 (100.00%), Query Frame = 3
Query: 150 MDERSLENENRDARKNNEDDFKSINLSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDSNMESLLQSGQILSDHISNTIFDLPAVQAVEMEFCKINYFKSFQSKALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISLDYYNKSLETLKXXXXXXXXXXXXXXYLEKLENLDVSSNNISELPLDLCLMKNIKTAHYFNGLHRIGLWVSSNPIEFPPKCVWNTTNIDVIYSFLQ 1451
MDERSLENENRDARKNNEDDFKSINLSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDSNMESLLQSGQILSDHISNTIFDLPAVQAVEMEFCKINYFKSFQSKALLELHISGNFFQEIPETVLNLNNLQILDLSKNLLLNINDDLIKLENLTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISLDYYNKSLETLKINHNNIKNIPNDIIYLEKLENLDVSSNNISELPLDLCLMKNIKTAHYFNGLHRIGLWVSSNPIEFPPKCVWNTTNIDVIYSFLQ
Sbjct: 1 MDERSLENENRDARKNNEDDFKSINLSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDSNMESLLQSGQILSDHISNTIFDLPAVQAVEMEFCKINYFKSFQSKALLELHISGNFFQEIPETVLNLNNLQILDLSKNLLLNINDDLIKLENLTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISLDYYNKSLETLKINHNNIKNIPNDIIYLEKLENLDVSSNNISELPLDLCLMKNIKTAHYFNGLHRIGLWVSSNPIEFPPKCVWNTTNIDVIYSFLQ 434
BLAST of Roc domain-containing protein vs. Planmine SMEST
Match: SMESG000016748.1 (SMESG000016748.1) HSP 1 Score: 83.1889 bits (204), Expect = 5.828e-16 Identity = 114/460 (24.78%), Postives = 212/460 (46.09%), Query Frame = 3
Query: 213 KSINLSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELR-SDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHL-------------------GEKIDSNMESLLQSGQILSDHISNT-----------IFDLPAVQAVEME----------FCKINYF----KSFQ--------SKALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISLDYYNKSLETLKXXXXXXXXXXXXXXYLEKLENLDVSSNNISELPLDLCLMKNIKTAHYFNGLHRIGLWVSSNPIEFPPKCVWNTTNIDV 1433
+S+++SN L V+PV + + + N S N +K+LP I L+ L+ +N+S N + +P+ + NLK L+ I+ +V IP++I ITSL ++ S N + L S +G+L L+ Q + +P +I C +++ L L N ++ IP L + +L+ L ++ + G I +SL+ + + + +IS +DL ++ E E FC + Y +F+ L+EL S NF ++P + +L +L+ L+LS N +L +L L+ L + N+I +I S+ M L LDLS N++ ++ + + L+ L +++N + N E+L +D S+N +E P++LC+ +I+ + + G + S P+E K +W +++
Sbjct: 101 QSLDVSNNKLEVIPVEIANLGHLEYFNCSHNKLKALPLTIFGLLKLQYMNLSHN--------QIQDIPEEIGNLKSLQTFLINSNEIVLIPSSISTITSLKTIEASNNQMCHLPISWVGSLKTLKLDGNQ---FQFIPSQIYDCCEMKYLSLAKNYLKFIPIELVKLRNLRQLDLSFNSIEYIPCEMGYWTKLVDFNIHGNNITYFPQSLIANHKFVCLNISGCQLKEFPLLLCNCYDLMELRVGENELNELPDKFQLFCNMKYLFMNNNNFELIPLQVCLLSTLVELDFSHNFLWQVPPGIFSLKHLRKLNLSFNNILIFPGCTAELSYLSELNVSHNKISEICDSISWMTFLYYLDLSFNELSTFPSAI-FQLRYLKYLNLSNNLLDNFSKTDKKWEELRTIDFSNNKFTEFPVELCVHDSIRKLVFD---QKEGTKIKSLPVEI--KNLWRLAELNL 543 HSP 2 Score: 53.5286 bits (127), Expect = 7.113e-7 Identity = 84/354 (23.73%), Postives = 150/354 (42.37%), Query Frame = 3
Query: 249 VPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDSNMESLLQSGQILSDHISNTIFDLPAVQAVEMEFCKINYFKSFQSKALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXXXXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISLDYYNKSLETLKXXXXXXXXXXXXXXYLEKLENLDVSSNNISELPLDLC 1310
VP ++ ++ +N+S+N I +D+SD E++ +S+ + + + + ++ + L+ L++S L IP I + L + S N + L I L +LQ++N H ++ +P+EI + L+T L+ N I IP ++ I SLKT+ + +N + LP I++ S ++ L + GN FQ IP + + + L L N ++ I L ++++L+ LDLS N I+ + + Y+ K L I+ NNI P +I K L++S + E PL LC
Sbjct: 44 VPKEIYFHPDVELINLSKNKI----SDLSD----EIIALSKLRHFFVNGNMLRTINVNLFYARGLQSLDVSNNKLEVIPVEIANLGHLEYFNCSHNKLKALPLTIFGLLKLQYMNLSHNQIQDIPEEIGNLKSLQTFLINSNEIVLIPSSISTITSLKTIEAS--------------------------NNQMCHLP-----------ISWVGSLKT-----LKLDGNQFQFIPSQIYDC-----------------------CEMKYLSLAKNYLKFIPIELVKLRNLRQLDLSFNSIEYIPCEMGYWTK-LVDFNIHGNNITYFPQSLIANHKFVCLNISGCQLKEFPLLLC 323
BLAST of Roc domain-containing protein vs. Planmine SMEST
Match: SMESG000023942.1 (SMESG000023942.1) HSP 1 Score: 70.4774 bits (171), Expect = 4.834e-12 Identity = 53/172 (30.81%), Postives = 83/172 (48.26%), Query Frame = 3
Query: 225 LSNTALTVVP--VTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSI 734
L+N + P V LF + LN+ N++ LP+ + L LE LNI N ++ LP + NLK L NI+ CNL + P +I ++ L L+IS+N I L + I L +L+WL++ + LP+ L + N+ I + +D+ LK LS
Sbjct: 417 LNNNTIIAPPNEVNLFPNL--VELNLEYNSLTMLPSSLCQLTKLEQLNIGNNQ--------LSALPNEIGNLKNLIKFNINHCNLSYFPHSICQLVQLEYLNISENFISFLPNSICQLKRLKWLDSGFNSISDLPESFSSLVDLYYINFQTNLFIKIRNVFSDLTKLKYLSF 578
BLAST of Roc domain-containing protein vs. Planmine SMEST
Match: SMESG000002900.1 (SMESG000002900.1) HSP 1 Score: 67.3958 bits (163), Expect = 3.475e-11 Identity = 50/165 (30.30%), Postives = 79/165 (47.88%), Query Frame = 3
Query: 213 KSINLSNTALTVVPVTLFKR-IEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTIL----------------PKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIGNLDQLQWLNAQHCGLKTLPQEIVGCEKLET 656
+++NL + +T +P + R + +THL++ +N + LP D+ NL LN+ N PDD+ L P ++K L+ L+ L++ E L F+P I + L +L + N + EL IGNL L +L L +LP EI LET
Sbjct: 364 QTLNLDHNQITQIPFGILSRAMFLTHLSMKDNLLTGLPPDVKSWENLVELNLGTNQL-AKVPDDIEYLINLEVLILSNNQFKRLPPTVKKLQKLRILDLEENLLEFLPPDIGCLQELQKLTVQSNRLTELPVSIGNLRNLTYLAVGENDLHSLPSEIGSMSALET 527 HSP 2 Score: 56.225 bits (134), Expect = 1.059e-7 Identity = 107/409 (26.16%), Postives = 186/409 (45.48%), Query Frame = 3
Query: 207 DFKSINLSNTALTVVPVTLFKRIEITHLNVSENNIKSLPADISDLVNLEVLNISRNGFHCTSPDDMTILPKSMKNLKCLKYLNISECNLVFIPATIWEITSLHQLDISKNNIGELRSDIG--NLDQLQWLNAQHCGLKTLPQEIVGCEKLETLLLYGNVIQTIPYLLADIGSLKTLSINLRHLGEKIDSNMESLLQSGQILSD--HISNTIFDLPA------VQAVEMEFCKINYFKSF------QSKALLELHISGNFFQEIPETVLNLNXXXXXXXXXXXXXXXXXXXXXX-XXXTTLYLQGNQIEKITKSLFQMKSLKVLDLSHNKIKKLTISLDYYNKSLETLKXXXXXXXXXXXXXXYLEKLENLDVSSNNISELPLDLCLMKNIK-TAHYFNGLHRIGLWVSS 1379
+ K + L + L +P L + + L + EN++ +LP +S L +L+I N + +P+ + L L +L + + + I + L L + +N I L S+ G L LQ + H L+ LP+ I C KL TL L N ++ IP + ++ +L+ + HL +++ L ++L + N I LP V + + NYF SF Q + L++ N +IP +L+ K+ LL +K ENL L L NQ+ K+ + + +L+VL LS+N+ K+L ++ K L L + N ++ +P DI L++L+ L V SN ++ELP+ + ++N+ A N LH + + S
Sbjct: 128 NLKELYLYSNKLINLPNELGNLVNLEILMLQENSLTALPDSLSQCRLLRILDIRHN--------KLCEIPQFVFKLHNLTHLLLRFNRIREVDPEIANLEKLQNLTLRENKIRLLPSNPGLEKLVNLQTFDISHNHLEMLPEAIGHCTKLTTLNLQHNELKLIPETIGNLTALERFGLRYNHL-----TSLPGSLSCCRMLCELNTEGNNISQLPEGLLTHLVHVTSIALSR-NYFSSFPLGGPQQFASTQTLNLDHNQITQIPFGILSRAMFLTHLSMKDNLLTGLPPDVKSWENLVELNLGTNQLAKVPDDIEYLINLEVLILSNNQFKRLPPTVKKLQK-LRILDLEENLLEFLPPDIGCLQELQKLTVQSNRLTELPVSIGNLRNLTYLAVGENDLHSLPSEIGS 521 The following BLAST results are available for this feature:
BLAST of Roc domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Roc domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Roc domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Roc domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Roc domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Roc domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Roc domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Roc domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Roc domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Roc domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Roc domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 2
BLAST of Roc domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Roc domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Roc domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30019942 ID=SMED30019942|Name=Roc domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=3012bpback to top protein sequence of SMED30019942-orf-1 >SMED30019942-orf-1 ID=SMED30019942-orf-1|Name=SMED30019942-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=943bp MDERSLENENRDARKNNEDDFKSINLSNTALTVVPVTLFKRIEITHLNVSback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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