slc16a-7
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30019936 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 4
Homology
BLAST of slc16a-7 vs. TrEMBL
Match: A0A0H3YF94 (Slc16a-7 OS=Schmidtea mediterranea OX=79327 GN=slc16a-7 PE=2 SV=1) HSP 1 Score: 895.575 bits (2313), Expect = 0.000e+0 Identity = 459/459 (100.00%), Postives = 459/459 (100.00%), Query Frame = 1 Query: 154 MNENEKSTSVNEEPTFINQEMTVWNWLVXXXXXXXXXXXXXXPHSFGTFIAHFKSDNNKTNNPSFYFVSQFEWNWLPALSSAVPCILLPLFVLIIQKINRSYQMLSALGFVIIAISCGLSSLVSLWYVFFFTYSLLYSIGSSLFLAVVVIILAEYFPVNHRFHVLATSLFQIGYPAAALIGNPLLAILIINYGWQVALKFTAFFEVITGVIIALLMKPVRDKSFCKHSEGSSENCPIKAELFSSTQRTLSATSMHYLAYSLELWTWLIAKFLNYLCWYGLRTNLVTYLVKSTNFGLEKSATLMSIYAGAEVIVAMSASIIGNGFKGYLMHIHVFSSMALAVLTGLYTIAITSYLSAVIVMICIGAAVQSSLNFGYPASVEVVKAKFDMKTGWILTNVAAGFGIFISPLFSGILMDRFNVKALFYAQSCGWALQAFLYLITLLIIKSNQNKLPTDYIEVK 1530 MNENEKSTSVNEEPTFINQEMTVWNWLVIIGTSLGSIISGIIPHSFGTFIAHFKSDNNKTNNPSFYFVSQFEWNWLPALSSAVPCILLPLFVLIIQKINRSYQMLSALGFVIIAISCGLSSLVSLWYVFFFTYSLLYSIGSSLFLAVVVIILAEYFPVNHRFHVLATSLFQIGYPAAALIGNPLLAILIINYGWQVALKFTAFFEVITGVIIALLMKPVRDKSFCKHSEGSSENCPIKAELFSSTQRTLSATSMHYLAYSLELWTWLIAKFLNYLCWYGLRTNLVTYLVKSTNFGLEKSATLMSIYAGAEVIVAMSASIIGNGFKGYLMHIHVFSSMALAVLTGLYTIAITSYLSAVIVMICIGAAVQSSLNFGYPASVEVVKAKFDMKTGWILTNVAAGFGIFISPLFSGILMDRFNVKALFYAQSCGWALQAFLYLITLLIIKSNQNKLPTDYIEVK Sbjct: 1 MNENEKSTSVNEEPTFINQEMTVWNWLVIIGTSLGSIISGIIPHSFGTFIAHFKSDNNKTNNPSFYFVSQFEWNWLPALSSAVPCILLPLFVLIIQKINRSYQMLSALGFVIIAISCGLSSLVSLWYVFFFTYSLLYSIGSSLFLAVVVIILAEYFPVNHRFHVLATSLFQIGYPAAALIGNPLLAILIINYGWQVALKFTAFFEVITGVIIALLMKPVRDKSFCKHSEGSSENCPIKAELFSSTQRTLSATSMHYLAYSLELWTWLIAKFLNYLCWYGLRTNLVTYLVKSTNFGLEKSATLMSIYAGAEVIVAMSASIIGNGFKGYLMHIHVFSSMALAVLTGLYTIAITSYLSAVIVMICIGAAVQSSLNFGYPASVEVVKAKFDMKTGWILTNVAAGFGIFISPLFSGILMDRFNVKALFYAQSCGWALQAFLYLITLLIIKSNQNKLPTDYIEVK 459
BLAST of slc16a-7 vs. TrEMBL
Match: A0A267GQ83 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig029081g1 PE=4 SV=1) HSP 1 Score: 236.884 bits (603), Expect = 2.390e-67 Identity = 153/433 (35.33%), Postives = 241/433 (55.66%), Query Frame = 1 Query: 160 ENEKSTSVNEEPTFINQE---MTVWNWLVXXXXXXXXXXXXXXPHSFGTFIAHFKSDNNKTNNPSFYFVSQFEWNWLPALSSAVPCILLPLFVLIIQKINRSYQMLSALGFVIIAISCGLSSLVSLWYVFFFTYSLLYSIGSSLFLAVVVIILAEYFPVNHRFHVLATSLFQIGYPAAALIGNPLLAILIINYGWQVALKFTAFFEVITGVIIALLMKPVRDK---SFCKHSEGSSENCPIKAELFSSTQRTLSATSMHYLAYSLELWTWLIAKFLNYLCWYGLRTNLVTYLVKSTNFGLEKSATLMSIYAGAEVIVAMSASIIGNGFKGYLMHIHVFSSMALAVLTGL-YTIAITSYLSAVIVMICIGAAVQSSLNFGYPASVEVVKAKFDMKTGWILTNVAAGFGIFISPLFSGILMDRFNVK-ALFYAQS 1434 E + + + +++ + ++ T+W+ L+ + TSL ++ +PHSFGT++ + + N S NW+ +S+VP I+LP+ ++ +++++A+ + + S +++ SL +FF +YSL+Y + S VV+ LAEYFPV H +HVLATSLFQIGYP AA+I NP A LI +GW+VA++ A I G +A L+KPV K F S+ ++ P S+ R + + M ++ W + K LNY CW+ LRTNLV Y+ + L +SA LM Y E+ V ++A ++G+ G L+H+H+ ++ +A+LTG+ + +A SY SA+ V IGA VQ SL F YPA+ EV + D+ T +T A G GI +SPL G+L D N LF A+S Sbjct: 36 ELQSTAADDKDQQQLEKDSAKCTLWHALICLATSLLILVEASVPHSFGTYLVAIREETNS---------SLLLLNWVTVATSSVPYIMLPVSTALLAHCVNWWRLVAAISCLGMGGSLLITAGQSLVPLFFLSYSLVYGVCSCALHGVVLSCLAEYFPVGHPWHVLATSLFQIGYPCAAVIFNPSAASLINRFGWRVAMRIMAAIVAIVGTCLACLLKPVGAKGLLDFSFKSDCTAAEQPAPVTAASAVCRCCTPSQM---LRRPQISIWFVGKLLNYACWFALRTNLVLYM-RLAGHSLAESAGLMIAYGLGEITVCLAACLLGDRIAGRLLHVHMVAACGMALLTGVWWFVASASYASALTVGCLIGAFVQLSLTFTYPAAAEVT--RLDLVTAGSVTLGAGGLGILVSPLIGGLLFDLVNAYWPLFLAES 453
BLAST of slc16a-7 vs. TrEMBL
Match: A0A1I8J8I8 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1) HSP 1 Score: 230.72 bits (587), Expect = 3.368e-61 Identity = 152/413 (36.80%), Postives = 232/413 (56.17%), Query Frame = 1 Query: 211 EMTVWNWLVXXXXXXXXXXXXXXPHSFGTFIAHFKSDNNKTNNPSFYFVSQFEWNWLPALSSAVPCILLPLFVLIIQKINRSYQMLSALGFVIIAISCGLSSLVSLWYVFFFTYSLLYSIGSSLFLAVVVIILAEYFPVNHRFHVLATSLFQIGYPAAALIGNPLLAILIINYGWQVALKFTAFFEVITGVIIALLMKPVRDK---SFCKHSEGSSENCPIKAELFSSTQRTLSATSMHYLAYSLELWTWLIAKFLNYLCWYGLRTNLVTYLVKSTNFGLEKSATLMSIYAGAEVIVAMSASIIGNGFKGYLMHIHVFSSMALAVLTGL-YTIAITSYLSAVIVMICIGAAVQSSLNFGYPASVEVVKAKFDMKTGWILTNVAAGFGIFISPLFSGILMDRFNVK-ALFYAQS 1434 + T+W+ L+ + TSL ++ +PHSFGT++ + + N S NW+ +S+VP I+LP+ ++ +++++A+ + + S +++ SL +FF +YSL+Y + S VV+ LAEYFPV H +HVLATSLFQIGYP AA+I NP A LI +GW+VA++ A I G +A L+KPV K F S+ ++ P S+ R + + M ++ W + K LNY CW+ LRTNLV Y+ + L +SA LM Y E+ V ++A ++G+ G L+H+H+ ++ +A+LTG+ + +A SY SA+ V IGA VQ SL F YPA+ EV + D+ T +T A G GI +SPL G+L D N LF A+S Sbjct: 614 KCTLWHALICLATSLLILVEASVPHSFGTYLVAIREETNS---------SLLLLNWVTVATSSVPYIMLPVSTALLAHCVNWWRLVAAISCLGMGGSLLITAGQSLVPLFFLSYSLVYGVCSCALHGVVLSCLAEYFPVGHPWHVLATSLFQIGYPCAAVIFNPSAASLINRFGWRVAMRIMAAIVAIVGTCLACLLKPVGAKGLLDFSFKSDCTAAEQPAPVTAASAVCRCCTPSQMLRRP---QISIWFVGKLLNYACWFALRTNLVLYM-RLAGHSLAESAGLMIAYGLGEITVCLAACLLGDRIAGRLLHVHMVAACGMALLTGVWWFVASASYASALTVGCLIGAFVQLSLTFTYPAAAEVT--RLDLVTAGSVTLGAGGLGILVSPLIGGLLFDLVNAYWPLFLAES 1011
BLAST of slc16a-7 vs. TrEMBL
Match: A0A2R2MNY3 (monocarboxylate transporter 13-like OS=Lingula unguis OX=7574 GN=LOC106159192 PE=4 SV=1) HSP 1 Score: 159.844 bits (403), Expect = 7.600e-39 Identity = 128/441 (29.02%), Postives = 215/441 (48.75%), Query Frame = 1 Query: 217 TVWNWLVXXXXXXXXXXXXXXPHSFGTFIAHFKSDNNKTNNPSFYFVSQFEWNWLPALSSAVPCILLPLFVLIIQKIN-RSYQMLSALGFVIIAISCGLSSLVSLWYVFFFTYSLLYSIGSSLFLAVVVIILAEYFPVNHRFHVLATSLFQIGYPAAALIGNPLLAILIINYGWQVALKFTAFFEVITGVIIALLMKPVRDKS-FCKHSEGSSENCPIKAELFSSTQRTLSATSMHYLAYSLELWTWLIAKFLNYLCWYGLRTNLVTYLVKSTNFGLEKSATLMSIYAGAEVIVAMSASIIGNGFKGYLMHIHVFSSMALAVLTGLYTIAITSYLSAVIVMICIGAAVQSSLNFGYPASVEVVKAKFDMKTGWILTNVAAGFGIFISPLFSGILMD-RFNVKALFYAQSCGWALQAFLYLITLLIIKSNQNKLPTDYIEVK 1530 V WL+ + ++I I +SFG F+ +D Y S E NW+ LS V P+ V +I+ + ++++ LG +I+ +SC SSLV+ F T+SLLY IGSS +I+ +YF +H HVLATS+ GYP +L+ NP+ A L+ +YGW+VA + + I GV P + + F +E +++ +++ S L E+ WL L+YL +Y NL Y +K S+ +++ + E I + AS++G F+G L+ ++ +S+ALAV+ ++ SY +++ +G + ++ + Y AS EV D+ W LTN+ +GFGI + P FSG++ D R + +FY +A+ F++ + K Q K +Y E+ Sbjct: 20 NVQGWLICFAVLIVTVIRSGITYSFGVFVVKLTND---------YHRSLAEQNWVGTLSFCVSLSFSPVSVALIRVVGPHGFRIVGLLGVIILTVSCIASSLVTSLEWMFLTHSLLYGIGSSFIYMASSLIIGDYFDKDHPQHVLATSILLCGYPVGSLVFNPINAWLVNSYGWRVAFRAASGMIFIAGVCCVATFAPRKTPAYFDLDNEEKTKDLSLRSCFGSCV----------VLKQRPEILLWLFGNTLSYLGFYMPFLNL-PYYMKLKGIKAIDSSWALTVLSLGECISYVVASLVGVFFRGKLVFSNILASLALAVICIVWPFVDASYAEIMVISSAMGVFLGLTIVYAYAASGEVTGLSLDV--AWALTNMWSGFGILLGPFFSGLIYDLRHSYDDVFYVNGGIFAVDLFVFGAIAALQKYRQYKGQFEYEEID 438
BLAST of slc16a-7 vs. TrEMBL
Match: A0A0R3TZH9 (MFS domain-containing protein OS=Rodentolepis nana OX=102285 GN=HNAJ_LOCUS13252 PE=4 SV=1) HSP 1 Score: 148.288 bits (373), Expect = 9.200e-35 Identity = 110/420 (26.19%), Postives = 208/420 (49.52%), Query Frame = 1 Query: 283 HSFGTFIAHFKSDNNKTNNPSFYFVSQFEWNWLPALSSAVPCILLPLFVLIIQKINRSYQMLSALGFVIIAISCGLSSLVSLWYVFFFTYSLLYSIGSSLFLAVVVIILAEYFPVNHRFHVLATSLFQIGYPAAALIGNPLLAILIINYGWQVALKFTAFFEVITGVIIALLMKPVRDKSFCKHSEGSSENCPIKAELFSSTQRTLSATSMHYLAYSLELWTWLIAKFLNYLCWYGLRTNLVTYLVKSTNFGLEKSATLMSIYAGAEVIVAMSASIIGNGFKGYLMHIHVFSSMALAVLTGLYTIAITSYLSAVIVMIC-IGAAVQSSLNFGYPASVEVVKAKFDMKTGWILTNVAAGFGIFISPLFSGILMDRFNVKALFYAQSCGWALQAFLYLITLLI-----IKSNQNKLPTDYIE 1524 +FG F++ +D F S E NW+ +AV L+P +I R+Y+ V I +SC S+ V F T+++L+ IGS+L L +I EYF HRFHVLAT+ F G P LI PL ++ I NYGW+ A + ++ ++ A++ +P +++S+ + + + E +S+ R + S+++L +L++ W + + ++ YGL N+ Y+ ++ + + + + E ++ ++IG+ +GYL ++ +++ AV+ L + + AV+V+ +GAAV + F Y S EV++ + + +T + AG G+ ++PL SG ++D F+ K F + + ++ L++I ++ I N+ KL + E Sbjct: 54 RAFGIFVSALHND--------FTNTSMTELNWIGDSYAAVGFFLMPFMTTLIVHAGRAYRTAMVAAGVFIFVSCFTSAAVPSPGYLFATHTVLHGIGSTLILCTTALITGEYFDKKHRFHVLATA-FVSGGPYGVLIFGPLFSLWIHNYGWREAFQICGTVFLMFNLLAAVIFQPKQNESYEEFANNEEQMDLEPVEHTASSGRGWALISINHLKENLQIIFWALDRLIHNFVMYGLLMNMTVYVTEAMEDKILDGSKVNLYFGIGESLIFTGGALIGDRIRGYLALFYMIGALSGAVIL-LIMQRLYQNVKAVLVLAGFLGAAVGTGNTFLYATSEEVIQIHGSI--AFPMTKMIAGIGMLLAPLLSGTVIDTFSFKGFFISMAILVCIRGGLFIIICVLLWRKRIIQNRKKLEREKGE 461
BLAST of slc16a-7 vs. Ensembl Nematostella
Match: EDO38356 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SD36]) HSP 1 Score: 57.7658 bits (138), Expect = 1.083e-8 Identity = 69/262 (26.34%), Postives = 119/262 (45.42%), Query Frame = 1 Query: 358 SQFEWNWLPALSSAVPCILLPLFVLIIQKINRSYQMLSALGFVIIAISCGLSSLVSLWYVFFFTYSLLYSIGSSLFLAVVVIILAEYFPVNHRFHVLATSLFQIGYPAAALIGNPLLAILIINYGWQVALKFTAFFEVITGVI-----IALLMKPVRDKSFCKHSEGSSENCPI----KAELFSSTQRTLSATSMHYLAYSLELWTWLIAKFLNYLCWYGLRTNLVTYLVKSTNFGL-EKSATLMSIYAGAEVIVAMSASII 1113 S+ + W+ +++ + + PL L+I + N +++ + LG + IS L+S FF+YS+LY +GS LF V +AEYF + LA G L P+L +L+ YGW+ F ++ GV+ + L + P K+ + P K L S T RT + Y+ + L + F++Y+ +LV Y ++S G+ EK A+ + I+ GA A+++SI+ Sbjct: 55 SRQKIAWVGSIAQCLTFLASPLAGLLIGRFN--FRVTAVLGSLTCCISLVLTSFTKASLHIFFSYSVLYGLGSCLFYMSCVYAVAEYF---EKRRGLALGFLTSGISVGVLAQGPVLQVLLDAYGWR------GTFRIMAGVVGVALFLLLTLDPNVKKAEIPDEQTDDVTKPQQSRGKCALVSETLRTPA-----YIIALVTLTLETLTAFVSYV-------HLVKYCMES---GIPEKDASELFIFIGA---CALASSIV 287 HSP 2 Score: 56.6102 bits (135), Expect = 2.534e-8 Identity = 67/269 (24.91%), Postives = 129/269 (47.96%), Query Frame = 1 Query: 358 SQFEWNWLPALSSAVPCILLPLFVLIIQKINRSYQMLSALGFVIIAISCGLSSLVSLWYVFFFTYSLLYSIGSSLFLAVVVIILAEYFPVNHRFHVLATSLFQIGYPAAALIGNPLLAILIINYGWQVALKFTAFFEVITGVI-IALLMKPVRDKSFCKHSEGSSENCPI-----KAELFSSTQRTLSATSMHYLAYSLELWTWLIA----------KFLNYLCWYGLRTNLVTYLVKSTNFGL-EKSATLMSIYAGAEVIVAMSASII 1113 S+ + W+ +++ + PL L+I K+ S+++ + LG + IS L+S FF+YS+LY +GS LF V +AEYF + LA G L P+L +L+ YGW++ F ++ GV+ +AL + +F + + ++ P+ + + F+ Q++ ++ ++ +L ++IA F++Y+ +LV Y ++S G+ EK A+ + I+ GA A+++SI+ Sbjct: 460 SRQKIAWVGSITQCLTFFASPLAGLLIGKL--SFRVTAVLGSLTCCISLVLTSFTKASLHIFFSYSVLYGLGSCLFYMSCVYAVAEYF---EKRRGLALGFLTSGISVGVLAQGPVLQVLLDAYGWRIT------FRIMAGVVGLALFLV----LTFDPNVQNATARVPVEISEEQTDDFTKPQQSRGKCAL--VSETLRTPAYIIALVTLTLETLTAFVSYV-------HLVKYCMES---GIPEKDASELFIFIGA---CALASSIV 698
BLAST of slc16a-7 vs. Ensembl Nematostella
Match: EDO35238 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SM28]) HSP 1 Score: 56.6102 bits (135), Expect = 1.410e-8 Identity = 64/281 (22.78%), Postives = 120/281 (42.70%), Query Frame = 1 Query: 154 MNENEKSTSVNEEPTFINQEMTVWNWLVXXXXXXXXXXXXXXPHSFGTFIAHFKSDNNKTNNPSFYFVSQFEWNWLPALSSAVPCILLPLFVLIIQKINRSYQMLSALGFVIIAISCGLSSLVSLWYVFFFTYSLLYSIGSSLFLAVVVIILAEYFPVNHRFHVLATSLFQIGYPAAALIGNPLLAILIINYGWQVALKFTAFFEVITGVIIALLMKPVRD------KSFCKHSEGSSENCPIKAELFSSTQRTLSATSMHYLAYSLELWTWLIAKFLNYL 978 M +KS EP ++ W WLV + + I ++FG + + V + E W+ +++ + +L PL + +KI ++ + +G +I A C L S+ Y+ TY L++ +G+S+ VIIL YF N R LA L G +L P+L +I G + ++ +A + + V+++ + +P+ K KH E + + +K FS + YL ++ L W++ F+ ++ Sbjct: 1 MRCCKKSLDEKPEP-LVDYPDGGWGWLVCLAAFITQFIVLGTMNNFGVIYVELLQE---------FKVGKAEAAWVGSITYGMMFLLGPLGTTLCKKIG--CRLTTVVGCIIAAGGCLLGSVAPNIYIMDLTYGLMFGVGASMCYFPSVIILGTYF--NKRLS-LANGLTSAGSGVGSLAMGPILQKVIEAVGMRNTMRISAAM-ISSIVLVSAIYRPINTPFLNAAKYETKHQEANKKKGCLKFLDFSLFKNK------AYLLWAASLSLWMLGYFVPFV 259
BLAST of slc16a-7 vs. Ensembl Nematostella
Match: EDO49501 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGB3]) HSP 1 Score: 51.2174 bits (121), Expect = 8.483e-7 Identity = 42/157 (26.75%), Postives = 78/157 (49.68%), Query Frame = 1 Query: 460 QMLSALGFVIIAISCGLSSLVSLWYVFFFTYSLLYSIGSSLFLAVVVIILAEYFPVNHRFHVLATSLFQIGYPAAALIGNPLLAILIINYGWQVALK-FTAFFEVITGVIIALLMKPV--RDKSFCKHSEGSSENCPIKAELFSSTQRTLSATSMHY 921 + ++ +G +I ++ +SS + +FTY +L IGSSL ++++A YF + LAT + G ALI PL L+ + GW+ ++ +AF +I ++ LL KP+ R++ C + S + + + +QR L + H+ Sbjct: 142 RKITIVGGIITSLGLLISSFCTSIKSMYFTYGILVGIGSSLSYLPALVMVAFYF---EKKRSLATGIAAAGGNIGALILAPLQQTLVEHIGWRNCMRCLSAFSSLI--IVCGLLFKPLPEREQKICMQEDSSDHD-----AILTRSQR-LKLRTCHF 287
BLAST of slc16a-7 vs. Ensembl Nematostella
Match: EDO46709 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RPB5]) HSP 1 Score: 50.0618 bits (118), Expect = 1.476e-6 Identity = 40/166 (24.10%), Postives = 79/166 (47.59%), Query Frame = 1 Query: 355 VSQFEWNWLPALSSAVPCILLPLFVLIIQKINRSYQMLSALGFVIIAISCGLSSLVSLWYVFFFTYSLLYSIGSSLFLAVVVIILAEYFPVNHRFHVLATSLFQIGYPAAALIGNPLLAILIINYGWQVALKFTAFFEVITGVIIALLMKPVRDKSFCKHSEGSSE 852 + + E W+ A++ + + PL ++ + S Q + +G ++ + L+S V + TY LL+ +GSSL ++IL EYF + L + G +L+ P++ L+ N GWQ ++ + F ++ I A L KP + + + S+ + + Sbjct: 42 LGKAETAWIGAMAMGLNFLCGPLTSILCTR--YSCQATAFIGALLSVLGLFLTSFVQEPPKMYLTYGLLFGVGSSLSFVSSIVILGEYF---QKRLALVNGIATSGSGVGSLVTGPVMNYLLANIGWQNCMRVLSGFAMLL-WIAAFLFKPNKRRVSTRPSKDAGK 201
BLAST of slc16a-7 vs. Ensembl Nematostella
Match: EDO48520 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RJ56]) HSP 1 Score: 48.521 bits (114), Expect = 5.271e-6 Identity = 88/373 (23.59%), Postives = 153/373 (41.02%), Query Frame = 1 Query: 454 SYQMLSALGFVIIAISCGLSSLVSLWYVFFFTYSLLYSIGSSLFLAVVVIILAEYFPVNHRFHVLATSLFQIGYPAAALIGNPLLAILIINYGWQVALKFTAFFEVITGVIIALLMKPVR-DKSFCKHSEGSSENCPIKAELFSSTQRTLSATSMHYLAYSLELWTWLIAKFLNYLCWYGLRTNLVTYLVK--STNFGL--EKSATLMSIYAGAEVIVAMSASIIGNGFKGYLMHIHVFSSMALAVLTGLYTIAITSYLSAVIVMICIG---AAVQSSLN--FGYPASVEVVKAKFDMKTGWILTNVAAGFGIFISPLFSGILMDRFNVKALFYAQSCGWALQAFL------YLITLLIIKSNQNKLPTDYIE 1524 S ++++ALG V+ A LSS V F T+S L G+ ++ +I YF + LA G + PL +I GW+ F+ + G+ + + D K E +E P + L R LSA Y Y+L + + IA F +Y +++ +L+K S GL +K++ L A V + A I + +++++ + + V+T L + +SY +I++ C G A ++++N F A + VK G ++T + G P +G+L DR + + S G L + L Y +I K+ Q P D ++ Sbjct: 93 SCRLIAALGHVLCAAGFLLSSTAPSLPVLFVTHSFLVGSGTCFIVSPSFLICERYF---KKRRSLAIGAISAGVGLGVMTWGPLSQQIINRLGWR------GFYRLTAGLFAGSIFLTLSFDPRIGKRPEPDAEA-PARRGLL-EILRDLSA--WKYRPYTLSVISVCIASFGHY--------SVIIHLMKFSSDEIGLSADKASRLYIASGMATVFARLVAGRICDLRSVRPIYVNLIAELCSGVVT-LCSPLASSYTHLIILIACYGLADGAFRTTINILFMQTAKPDPVKVASAYGGGMMMTAIPTAAG----PALAGMLADRSGSYRVAFFVSGGITLLSTLAYLPEIYKDIQVICKAKQQG-PEDRLD 438
BLAST of slc16a-7 vs. Planmine SMEST
Match: SMESG000016424.1 (SMESG000016424.1) HSP 1 Score: 887.486 bits (2292), Expect = 0.000e+0 Identity = 455/459 (99.13%), Postives = 458/459 (99.78%), Query Frame = 1 Query: 154 MNENEKSTSVNEEPTFINQEMTVWNWLVXXXXXXXXXXXXXXPHSFGTFIAHFKSDNNKTNNPSFYFVSQFEWNWLPALSSAVPCILLPLFVLIIQKINRSYQMLSALGFVIIAISCGLSSLVSLWYVFFFTYSLLYSIGSSLFLAVVVIILAEYFPVNHRFHVLATSLFQIGYPAAALIGNPLLAILIINYGWQVALKFTAFFEVITGVIIALLMKPVRDKSFCKHSEGSSENCPIKAELFSSTQRTLSATSMHYLAYSLELWTWLIAKFLNYLCWYGLRTNLVTYLVKSTNFGLEKSATLMSIYAGAEVIVAMSASIIGNGFKGYLMHIHVFSSMALAVLTGLYTIAITSYLSAVIVMICIGAAVQSSLNFGYPASVEVVKAKFDMKTGWILTNVAAGFGIFISPLFSGILMDRFNVKALFYAQSCGWALQAFLYLITLLIIKSNQNKLPTDYIEVK 1530 MNENEKSTSVN+EPTFINQEMTVWNWLVIIGTSLGSIISGIIPHSFGTFIAHFKSDNNKTNNPSFYFVSQFEWNWLP+LSSAVPCILLPLFVLIIQKINRSYQMLSALGFVIIAISCGLSSLVSLWYVFFFTYSLLYSIGSSLFLAVVVIILAEYFPVNHRFHVLATSLFQIGYPAAALIGNPLLAILIINYGWQVALKFTAFFEVITGVIIALLMKPVRDKSFCKHSEGSSENCPIKAEL SSTQRTLSATSMHYLAYSLELWTWLIAKFLNYLCWYGLRTNLVTYLVKSTNFGLEKSATLMSIYAGAEVIVAMSASIIGNGFKGYLMHIHVFSSMALAVLTGLYTIAITSYLSAVI+MICIGAAVQSSLNFGYPASVEVVKAKFDMKTGWILTNVAAGFGIFISPLFSGILMDRFNVKALFYAQSCGWALQAFLYLITLLIIKSNQNKLPTDYIEVK Sbjct: 1 MNENEKSTSVNKEPTFINQEMTVWNWLVIIGTSLGSIISGIIPHSFGTFIAHFKSDNNKTNNPSFYFVSQFEWNWLPSLSSAVPCILLPLFVLIIQKINRSYQMLSALGFVIIAISCGLSSLVSLWYVFFFTYSLLYSIGSSLFLAVVVIILAEYFPVNHRFHVLATSLFQIGYPAAALIGNPLLAILIINYGWQVALKFTAFFEVITGVIIALLMKPVRDKSFCKHSEGSSENCPIKAELSSSTQRTLSATSMHYLAYSLELWTWLIAKFLNYLCWYGLRTNLVTYLVKSTNFGLEKSATLMSIYAGAEVIVAMSASIIGNGFKGYLMHIHVFSSMALAVLTGLYTIAITSYLSAVILMICIGAAVQSSLNFGYPASVEVVKAKFDMKTGWILTNVAAGFGIFISPLFSGILMDRFNVKALFYAQSCGWALQAFLYLITLLIIKSNQNKLPTDYIEVK 459
BLAST of slc16a-7 vs. Planmine SMEST
Match: SMESG000023800.1 (SMESG000023800.1) HSP 1 Score: 887.1 bits (2291), Expect = 0.000e+0 Identity = 455/459 (99.13%), Postives = 458/459 (99.78%), Query Frame = 1 Query: 154 MNENEKSTSVNEEPTFINQEMTVWNWLVXXXXXXXXXXXXXXPHSFGTFIAHFKSDNNKTNNPSFYFVSQFEWNWLPALSSAVPCILLPLFVLIIQKINRSYQMLSALGFVIIAISCGLSSLVSLWYVFFFTYSLLYSIGSSLFLAVVVIILAEYFPVNHRFHVLATSLFQIGYPAAALIGNPLLAILIINYGWQVALKFTAFFEVITGVIIALLMKPVRDKSFCKHSEGSSENCPIKAELFSSTQRTLSATSMHYLAYSLELWTWLIAKFLNYLCWYGLRTNLVTYLVKSTNFGLEKSATLMSIYAGAEVIVAMSASIIGNGFKGYLMHIHVFSSMALAVLTGLYTIAITSYLSAVIVMICIGAAVQSSLNFGYPASVEVVKAKFDMKTGWILTNVAAGFGIFISPLFSGILMDRFNVKALFYAQSCGWALQAFLYLITLLIIKSNQNKLPTDYIEVK 1530 MNENEKSTSVN+EPTFINQEMTVWNWLVIIGTSLGSIISGIIPHSFGTFIAHFKSDNNKTNNPSFYFVSQFEWNWLPALSSAVPCILLPLFVLIIQKINRSYQMLSALGFVIIAISCGLSSLVSLWYVFFFTYSLLYSIGSSLFLAVVVIILAEYFPVNH+FHVLATSLFQIGYPAAALIGNPLLAILIINYGWQVALKFTAFFEVITGVIIALLMKPVRDKSFCKHSEGSSENCPIKAEL SSTQRTLSATSMHYLAYSLELWTWLIAKFLNYLCWYGLRTNLVTYLVKSTNFGLEKSATLMSIYAGAEVIVAMSASIIGNGFKGYLMHIHVFSSMALAVLTGLYTIAITSYLSAVI+MICIGAAVQSSLNFGYPASVEVVKAKFDMKTGWILTNVAAGFGIFISPLFSGILMDRFNVKALFYAQSCGWALQAFLYLITLLIIKSNQNKLPTDYIEVK Sbjct: 1 MNENEKSTSVNKEPTFINQEMTVWNWLVIIGTSLGSIISGIIPHSFGTFIAHFKSDNNKTNNPSFYFVSQFEWNWLPALSSAVPCILLPLFVLIIQKINRSYQMLSALGFVIIAISCGLSSLVSLWYVFFFTYSLLYSIGSSLFLAVVVIILAEYFPVNHKFHVLATSLFQIGYPAAALIGNPLLAILIINYGWQVALKFTAFFEVITGVIIALLMKPVRDKSFCKHSEGSSENCPIKAELSSSTQRTLSATSMHYLAYSLELWTWLIAKFLNYLCWYGLRTNLVTYLVKSTNFGLEKSATLMSIYAGAEVIVAMSASIIGNGFKGYLMHIHVFSSMALAVLTGLYTIAITSYLSAVILMICIGAAVQSSLNFGYPASVEVVKAKFDMKTGWILTNVAAGFGIFISPLFSGILMDRFNVKALFYAQSCGWALQAFLYLITLLIIKSNQNKLPTDYIEVK 459
BLAST of slc16a-7 vs. Planmine SMEST
Match: SMESG000023798.1 (SMESG000023798.1) HSP 1 Score: 453.751 bits (1166), Expect = 2.466e-155 Identity = 234/439 (53.30%), Postives = 323/439 (73.58%), Query Frame = 1 Query: 208 QEMTVWNWLVXXXXXXXXXXXXXXPHSFGTFIAHFKSDNNKTNNPSFYFVSQFEWNWLPALSSAVPCILLPLFVLIIQKINRSYQMLSALGFVIIAISCGLSSLVSLWYVFFFTYSLLYSIGSSLFLAVVVIILAEYFPVNHRFHVLATSLFQIGYPAAALIGNPLLAILIINYGWQVALKFTAFFEVITGVIIALLMKPVRDKSFCKHSEGSSENCPIKAELFSSTQRTLSATSMHYLAYSLELWTWLIAKFLNYLCWYGLRTNLVTYLVKSTNFGLEKSATLMSIYAGAEVIVAMSASIIGNGFKGYLMHIHVFSSMALAVLTGLYTIAITSYLSAVIVMICIGAAVQSSLNFGYPASVEVVKAKFDMKTGWILTNVAAGFGIFISPLFSGILMDRFNVKALFYAQSCGWALQAFLYLITLLIIKSNQNKLPTDYIE 1524 + +++W+ LVIIGT+LG+II G++PHSFGT IA+FKS NN T +PSFY SQF N+LPA SSA PCILLPLFV+IIQ+ + YQ++SAL F+++AISCGLSSLV++W + F TYS++YSIG+SLFL VV+I+ AEYFP HRFHVLATSL+QIGYP AAL GNP+LA L+ YGWQ + K A +++ G I++ +MK + K +N K E S + + S ++ + ++ WL+ K++NY+CWY LRTN+VTYLVKST FGL SATLMS+YA +E+ +A+ AS+ G+ F+G+L+HIH+ SS++LA+LT +YT+ +TSY+SAV++M+ IG ++Q SL+FGYPA+ EV + D+K GW+LTNV+AGFGI SPL SG LMD+ +K+L YAQ GW LQ L+ TL+ +K + + IE Sbjct: 6 KTLSIWHVLVIIGTALGTIIEGLVPHSFGTLIAYFKSKNN-TESPSFYSASQFHLNFLPASSSAFPCILLPLFVVIIQRYFKLYQIISALAFLLLAISCGLSSLVNIWPILFLTYSVIYSIGASLFLGVVIIVAAEYFPKEHRFHVLATSLYQIGYPMAALFGNPILAYLLTKYGWQNSFKIIAVIQILLGSILSCMMKSIDSKGLSYIKTTEVDNGKTKEESTKSNESSHSGFQIN-IKSDYQVIPWLLGKYINYMCWYALRTNIVTYLVKSTTFGLSNSATLMSVYAASEISIALIASLFGDFFRGWLVHIHLLSSISLAILTAIYTVVLTSYISAVLLMMAIGVSIQLSLSFGYPAAAEVWDSNSDIKVGWVLTNVSAGFGIISSPLISGFLMDKVGMKSLLYAQCIGWILQTILFAATLICMKYKRYQTEYQNIE 442
BLAST of slc16a-7 vs. Planmine SMEST
Match: SMESG000016446.1 (SMESG000016446.1) HSP 1 Score: 453.751 bits (1166), Expect = 2.466e-155 Identity = 234/439 (53.30%), Postives = 323/439 (73.58%), Query Frame = 1 Query: 208 QEMTVWNWLVXXXXXXXXXXXXXXPHSFGTFIAHFKSDNNKTNNPSFYFVSQFEWNWLPALSSAVPCILLPLFVLIIQKINRSYQMLSALGFVIIAISCGLSSLVSLWYVFFFTYSLLYSIGSSLFLAVVVIILAEYFPVNHRFHVLATSLFQIGYPAAALIGNPLLAILIINYGWQVALKFTAFFEVITGVIIALLMKPVRDKSFCKHSEGSSENCPIKAELFSSTQRTLSATSMHYLAYSLELWTWLIAKFLNYLCWYGLRTNLVTYLVKSTNFGLEKSATLMSIYAGAEVIVAMSASIIGNGFKGYLMHIHVFSSMALAVLTGLYTIAITSYLSAVIVMICIGAAVQSSLNFGYPASVEVVKAKFDMKTGWILTNVAAGFGIFISPLFSGILMDRFNVKALFYAQSCGWALQAFLYLITLLIIKSNQNKLPTDYIE 1524 + +++W+ LVIIGT+LG+II G++PHSFGT IA+FKS NN T +PSFY SQF N+LPA SSA PCILLPLFV+IIQ+ + YQ++SAL F+++AISCGLSSLV++W + F TYS++YSIG+SLFL VV+I+ AEYFP HRFHVLATSL+QIGYP AAL GNP+LA L+ YGWQ + K A +++ G I++ +MK + K +N K E S + + S ++ + ++ WL+ K++NY+CWY LRTN+VTYLVKST FGL SATLMS+YA +E+ +A+ AS+ G+ F+G+L+HIH+ SS++LA+LT +YT+ +TSY+SAV++M+ IG ++Q SL+FGYPA+ EV + D+K GW+LTNV+AGFGI SPL SG LMD+ +K+L YAQ GW LQ L+ TL+ +K + + IE Sbjct: 6 KTLSIWHVLVIIGTALGTIIEGLVPHSFGTLIAYFKSKNN-TESPSFYSASQFHLNFLPASSSAFPCILLPLFVVIIQRYFKLYQIISALAFLLLAISCGLSSLVNIWPILFLTYSVIYSIGASLFLGVVIIVAAEYFPKEHRFHVLATSLYQIGYPMAALFGNPILAYLLTKYGWQNSFKIIAVIQILLGSILSCMMKSIDSKGLSYIKTTEVDNGKTKEESTKSNESSHSGFQIN-IKSDYQVIPWLLGKYINYMCWYALRTNIVTYLVKSTTFGLSNSATLMSVYAASEISIALIASLFGDFFRGWLVHIHLLSSISLAILTAIYTVVLTSYISAVLLMMAIGVSIQLSLSFGYPAAAEVWDSNSDIKVGWVLTNVSAGFGIISSPLISGFLMDKVGMKSLLYAQCIGWILQTILFAATLICMKYKRYQTEYQNIE 442
BLAST of slc16a-7 vs. Planmine SMEST
Match: SMESG000011418.1 (SMESG000011418.1) HSP 1 Score: 130.954 bits (328), Expect = 1.028e-32 Identity = 113/388 (29.12%), Postives = 183/388 (47.16%), Query Frame = 1 Query: 283 HSFGTFIAHFKSDNNKTNNPSFYFVSQFEWNWLPALSSAVPCILLPLFVLIIQKINRSYQMLSALGFVIIAISCGLSSLVSLWYVFFFTYSLLYSIGSSLFLAVVVIILAEYFPVNHRFHVLATSLFQIGYPAAALIGNPLLAILIINYGWQVALKFTA--FFEVITGVIIALLMKPVRDKSFCKHSEGSSENCPIKAELFSSTQRTLSATSMHYLAYSLELWTWLIAKFLNYLCWYGLRTNLVTYLVKSTNFG---LEKSATLMSIYAGAEVIVAMSASIIGNGFKGYLMHIHVFSSMALAVLTGLYTIAITSYLSAVI---VMICIGAAVQSSLNFGYPASVEVVKAKFDMKTGWILTNVAAGFGIFISPLFSGILMDRFNVKALF 1422 +FG FI+ F+S N T S E NW+ SAV L+P + + NRSYQ +++ SC L+S V+ F T+++L+ IGS+ L+ +I+ EYF NHR+HVLATSL G P +LI PL ++ +Y W+ + A FF I+ I+A + KP KS + E P S+ YL + +++ W I + YGL NL T L++S G LE A + + E I+ +++IG+ +G L H+ + A +L + ++ Y A+I + + GA V + + + + + + L+N+ FG+ I+P+FSG+L+D + LF Sbjct: 37 RTFGIFISAFRSTFNGT--------SMVELNWVGDSYSAVAFFLMPFITSFVHR-NRSYQKGMLAASILVFCSCMLTSFVTNAAELFITHTVLHGIGSAFILSTSALIIGEYFDKNHRYHVLATSL-TTGGPYGSLIFGPLYGFMVQHYDWRFTFRVIAILFFVEISAGILAYVPKPDYQKS--EEIENYEGAFP----------------SLKYLIQNKQIFLWGIDRICTSSILYGLLMNL-TDLLRSMLNGTENLEGGAKINLMMGVGESIIFTISAVIGDKIRGKLPFFHLIGA-AFTLLMLILMKTVSYYPYAIIAFSIFLGAGAGVGNCMLYASSEEITFLHGSISLP----LSNMMMAFGMIIAPIFSGLLIDMYGFLGLF 390 The following BLAST results are available for this feature:
BLAST of slc16a-7 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 0
BLAST of slc16a-7 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 0
BLAST of slc16a-7 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 0
BLAST of slc16a-7 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 0
BLAST of slc16a-7 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 0
BLAST of slc16a-7 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 0
BLAST of slc16a-7 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 0
BLAST of slc16a-7 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of slc16a-7 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 0
BLAST of slc16a-7 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 0
BLAST of slc16a-7 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of slc16a-7 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of slc16a-7 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 0
BLAST of slc16a-7 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Cross References
External references for this transcript
Sequences
The following sequences are available for this feature:
transcript sequence >SMED30019936 ID=SMED30019936|Name=slc16a-7|organism=Schmidtea mediterranea sexual|type=transcript|length=1824bpback to top protein sequence of SMED30019936-orf-1 >SMED30019936-orf-1 ID=SMED30019936-orf-1|Name=SMED30019936-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=460bp MNENEKSTSVNEEPTFINQEMTVWNWLVIIGTSLGSIISGIIPHSFGTFIback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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