Potassium voltage-gated channel subfamily A member 2
|
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30019915 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 6
Homology
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Human
Match: KCNA2 (potassium voltage-gated channel subfamily A member 2 [Source:HGNC Symbol;Acc:HGNC:6220]) HSP 1 Score: 383.645 bits (984), Expect = 1.339e-127 Identity = 191/393 (48.60%), Postives = 264/393 (67.18%), Query Frame = 1
Query: 391 YDLKEKVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTLEVIE-LPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFF---NKSHCVSGA--------------APNFLDVFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVLVT--FDCDGAKKSASLAFLRVIRLIRVF---KLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHKT 1500
++ E+VVINISGL FET L + P TLLGDP KR Y+D R EYFFDR RP+F++I YYQ+GG+++RPVNVP +IF E+ FY++ + ++ +++DEG+ E LP N+ +R +W+LFE+PE+S A +A++SV ++SIV FC+ET P F N+ SG + +F D FFI+ET+C WF+ E RF +CPSK F +I NIID+ A+IPY++TL L D +++ SLA LRVIRL+RVF KL++HS GLQ+L T +AS+ LGL + L + +ILFSS +Y+AE +SQ SIPDAFWWA+++M TVGYGD VP I GK+VGS+CA++GVLT+A+PVP+I NFN FY +T
Sbjct: 29 HECCERVVINISGLRFETQLKTLAQFPETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFYELGEEAMEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPARIIAIVSVMVILISIVSFCLETLPIFRDENEDMHGSGVTFHTYSNSTIGYQQSTSFTDPFFIVETLCIIWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEKPEDAQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADERESQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRET 421
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Human
Match: KCNA2 (potassium voltage-gated channel subfamily A member 2 [Source:HGNC Symbol;Acc:HGNC:6220]) HSP 1 Score: 383.645 bits (984), Expect = 1.339e-127 Identity = 191/393 (48.60%), Postives = 264/393 (67.18%), Query Frame = 1
Query: 391 YDLKEKVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTLEVIE-LPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFF---NKSHCVSGA--------------APNFLDVFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVLVT--FDCDGAKKSASLAFLRVIRLIRVF---KLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHKT 1500
++ E+VVINISGL FET L + P TLLGDP KR Y+D R EYFFDR RP+F++I YYQ+GG+++RPVNVP +IF E+ FY++ + ++ +++DEG+ E LP N+ +R +W+LFE+PE+S A +A++SV ++SIV FC+ET P F N+ SG + +F D FFI+ET+C WF+ E RF +CPSK F +I NIID+ A+IPY++TL L D +++ SLA LRVIRL+RVF KL++HS GLQ+L T +AS+ LGL + L + +ILFSS +Y+AE +SQ SIPDAFWWA+++M TVGYGD VP I GK+VGS+CA++GVLT+A+PVP+I NFN FY +T
Sbjct: 29 HECCERVVINISGLRFETQLKTLAQFPETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFYELGEEAMEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPARIIAIVSVMVILISIVSFCLETLPIFRDENEDMHGSGVTFHTYSNSTIGYQQSTSFTDPFFIVETLCIIWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEKPEDAQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADERESQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRET 421
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Human
Match: KCNA2 (potassium voltage-gated channel subfamily A member 2 [Source:HGNC Symbol;Acc:HGNC:6220]) HSP 1 Score: 383.645 bits (984), Expect = 1.339e-127 Identity = 191/393 (48.60%), Postives = 264/393 (67.18%), Query Frame = 1
Query: 391 YDLKEKVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTLEVIE-LPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFF---NKSHCVSGA--------------APNFLDVFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVLVT--FDCDGAKKSASLAFLRVIRLIRVF---KLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHKT 1500
++ E+VVINISGL FET L + P TLLGDP KR Y+D R EYFFDR RP+F++I YYQ+GG+++RPVNVP +IF E+ FY++ + ++ +++DEG+ E LP N+ +R +W+LFE+PE+S A +A++SV ++SIV FC+ET P F N+ SG + +F D FFI+ET+C WF+ E RF +CPSK F +I NIID+ A+IPY++TL L D +++ SLA LRVIRL+RVF KL++HS GLQ+L T +AS+ LGL + L + +ILFSS +Y+AE +SQ SIPDAFWWA+++M TVGYGD VP I GK+VGS+CA++GVLT+A+PVP+I NFN FY +T
Sbjct: 29 HECCERVVINISGLRFETQLKTLAQFPETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFYELGEEAMEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPARIIAIVSVMVILISIVSFCLETLPIFRDENEDMHGSGVTFHTYSNSTIGYQQSTSFTDPFFIVETLCIIWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEKPEDAQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADERESQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRET 421
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Human
Match: KCNA2 (potassium voltage-gated channel subfamily A member 2 [Source:HGNC Symbol;Acc:HGNC:6220]) HSP 1 Score: 383.645 bits (984), Expect = 1.339e-127 Identity = 191/393 (48.60%), Postives = 264/393 (67.18%), Query Frame = 1
Query: 391 YDLKEKVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTLEVIE-LPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFF---NKSHCVSGA--------------APNFLDVFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVLVT--FDCDGAKKSASLAFLRVIRLIRVF---KLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHKT 1500
++ E+VVINISGL FET L + P TLLGDP KR Y+D R EYFFDR RP+F++I YYQ+GG+++RPVNVP +IF E+ FY++ + ++ +++DEG+ E LP N+ +R +W+LFE+PE+S A +A++SV ++SIV FC+ET P F N+ SG + +F D FFI+ET+C WF+ E RF +CPSK F +I NIID+ A+IPY++TL L D +++ SLA LRVIRL+RVF KL++HS GLQ+L T +AS+ LGL + L + +ILFSS +Y+AE +SQ SIPDAFWWA+++M TVGYGD VP I GK+VGS+CA++GVLT+A+PVP+I NFN FY +T
Sbjct: 29 HECCERVVINISGLRFETQLKTLAQFPETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFYELGEEAMEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPARIIAIVSVMVILISIVSFCLETLPIFRDENEDMHGSGVTFHTYSNSTIGYQQSTSFTDPFFIVETLCIIWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEKPEDAQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADERESQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRET 421
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Human
Match: KCNA2 (potassium voltage-gated channel subfamily A member 2 [Source:HGNC Symbol;Acc:HGNC:6220]) HSP 1 Score: 383.645 bits (984), Expect = 1.339e-127 Identity = 191/393 (48.60%), Postives = 264/393 (67.18%), Query Frame = 1
Query: 391 YDLKEKVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTLEVIE-LPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFF---NKSHCVSGA--------------APNFLDVFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVLVT--FDCDGAKKSASLAFLRVIRLIRVF---KLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHKT 1500
++ E+VVINISGL FET L + P TLLGDP KR Y+D R EYFFDR RP+F++I YYQ+GG+++RPVNVP +IF E+ FY++ + ++ +++DEG+ E LP N+ +R +W+LFE+PE+S A +A++SV ++SIV FC+ET P F N+ SG + +F D FFI+ET+C WF+ E RF +CPSK F +I NIID+ A+IPY++TL L D +++ SLA LRVIRL+RVF KL++HS GLQ+L T +AS+ LGL + L + +ILFSS +Y+AE +SQ SIPDAFWWA+++M TVGYGD VP I GK+VGS+CA++GVLT+A+PVP+I NFN FY +T
Sbjct: 29 HECCERVVINISGLRFETQLKTLAQFPETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFYELGEEAMEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPARIIAIVSVMVILISIVSFCLETLPIFRDENEDMHGSGVTFHTYSNSTIGYQQSTSFTDPFFIVETLCIIWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEKPEDAQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADERESQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRET 421
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Celegans
Match: shk-1 (Potassium voltage-gated channel protein shk-1 [Source:UniProtKB/Swiss-Prot;Acc:Q8I4B0]) HSP 1 Score: 302.753 bits (774), Expect = 2.279e-97 Identity = 166/400 (41.50%), Postives = 253/400 (63.25%), Query Frame = 1
Query: 343 RRNALEYSSLRSGPFQYDLKEKVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTL-EVIELPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFFNKSHCVSGAA-PNFLD--------VFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVLVTFDCDGAKKSASLAF-----LRVIRLIRVFKLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHK 1497
+R + SS + P+ + V IN+SG+ F+T+ L+ +P +LLGD +KR ++ E+FFDR+R FESI YQ+GG++KRP VP +IFL E+ F+Q+ +++ + EG+ + + +P NK +R IW L E+P++S+SA +A +S+A LSI+ FC ET P + ++ +A LD FF +E +C WFTIE+ RFISCP KV F + NIID A+ P++V F D +K ++S++F LR++R+ RVFKL++HS GLQ+L TFR+S++ L + ++++++LF+S +Y+AE G P+S+ SIP +FW+ ++TM TVGYGD VP GK+VG +CA+ GVLTLA+PVPII NF FY +
Sbjct: 27 QRGTPDTSSTQGHPYT---DQIVTINVSGMRFQTFESTLSRYPNSLLGDRNKRQHFFVSDTNEFFFDRHRTTFESILYIYQSGGRVKRPEIVPIDIFLKEMRFFQMGDDLLEEFWIAEGYEKPKEVMMPNNKTQRKIWELMEYPDSSLSARIIAFISIAVIALSIISFCWETVPSDIEEKPINNSATAELLDEMDEKHYSPFFWIELMCILWFTIELILRFISCPCKVTFATSVLNIIDFVAIAPFFVNF------FFADTSKSNSSMSFAVLRVLRLVRVFRVFKLSRHSVGLQILGKTFRSSVQEFCLLIFFMAIALVLFASGMYFAEQGEPNSKFTSIPASFWFVLVTMTTVGYGDLVPLSPFGKVVGGMCAMIGVLTLALPVPIIVANFKHFYRQE 417
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Celegans
Match: shk-1 (Potassium voltage-gated channel protein shk-1 [Source:UniProtKB/Swiss-Prot;Acc:Q8I4B0]) HSP 1 Score: 302.753 bits (774), Expect = 2.279e-97 Identity = 166/400 (41.50%), Postives = 253/400 (63.25%), Query Frame = 1
Query: 343 RRNALEYSSLRSGPFQYDLKEKVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTL-EVIELPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFFNKSHCVSGAA-PNFLD--------VFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVLVTFDCDGAKKSASLAF-----LRVIRLIRVFKLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHK 1497
+R + SS + P+ + V IN+SG+ F+T+ L+ +P +LLGD +KR ++ E+FFDR+R FESI YQ+GG++KRP VP +IFL E+ F+Q+ +++ + EG+ + + +P NK +R IW L E+P++S+SA +A +S+A LSI+ FC ET P + ++ +A LD FF +E +C WFTIE+ RFISCP KV F + NIID A+ P++V F D +K ++S++F LR++R+ RVFKL++HS GLQ+L TFR+S++ L + ++++++LF+S +Y+AE G P+S+ SIP +FW+ ++TM TVGYGD VP GK+VG +CA+ GVLTLA+PVPII NF FY +
Sbjct: 27 QRGTPDTSSTQGHPYT---DQIVTINVSGMRFQTFESTLSRYPNSLLGDRNKRQHFFVSDTNEFFFDRHRTTFESILYIYQSGGRVKRPEIVPIDIFLKEMRFFQMGDDLLEEFWIAEGYEKPKEVMMPNNKTQRKIWELMEYPDSSLSARIIAFISIAVIALSIISFCWETVPSDIEEKPINNSATAELLDEMDEKHYSPFFWIELMCILWFTIELILRFISCPCKVTFATSVLNIIDFVAIAPFFVNF------FFADTSKSNSSMSFAVLRVLRLVRVFRVFKLSRHSVGLQILGKTFRSSVQEFCLLIFFMAIALVLFASGMYFAEQGEPNSKFTSIPASFWFVLVTMTTVGYGDLVPLSPFGKVVGGMCAMIGVLTLALPVPIIVANFKHFYRQE 417
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Celegans
Match: shk-1 (Potassium voltage-gated channel protein shk-1 [Source:UniProtKB/Swiss-Prot;Acc:Q8I4B0]) HSP 1 Score: 303.138 bits (775), Expect = 2.336e-97 Identity = 166/400 (41.50%), Postives = 253/400 (63.25%), Query Frame = 1
Query: 343 RRNALEYSSLRSGPFQYDLKEKVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTL-EVIELPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFFNKSHCVSGAA-PNFLD--------VFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVLVTFDCDGAKKSASLAF-----LRVIRLIRVFKLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHK 1497
+R + SS + P+ + V IN+SG+ F+T+ L+ +P +LLGD +KR ++ E+FFDR+R FESI YQ+GG++KRP VP +IFL E+ F+Q+ +++ + EG+ + + +P NK +R IW L E+P++S+SA +A +S+A LSI+ FC ET P + ++ +A LD FF +E +C WFTIE+ RFISCP KV F + NIID A+ P++V F D +K ++S++F LR++R+ RVFKL++HS GLQ+L TFR+S++ L + ++++++LF+S +Y+AE G P+S+ SIP +FW+ ++TM TVGYGD VP GK+VG +CA+ GVLTLA+PVPII NF FY +
Sbjct: 40 QRGTPDTSSTQGHPYT---DQIVTINVSGMRFQTFESTLSRYPNSLLGDRNKRQHFFVSDTNEFFFDRHRTTFESILYIYQSGGRVKRPEIVPIDIFLKEMRFFQMGDDLLEEFWIAEGYEKPKEVMMPNNKTQRKIWELMEYPDSSLSARIIAFISIAVIALSIISFCWETVPSDIEEKPINNSATAELLDEMDEKHYSPFFWIELMCILWFTIELILRFISCPCKVTFATSVLNIIDFVAIAPFFVNF------FFADTSKSNSSMSFAVLRVLRLVRVFRVFKLSRHSVGLQILGKTFRSSVQEFCLLIFFMAIALVLFASGMYFAEQGEPNSKFTSIPASFWFVLVTMTTVGYGDLVPLSPFGKVVGGMCAMIGVLTLALPVPIIVANFKHFYRQE 430
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Celegans
Match: shk-1 (Potassium voltage-gated channel protein shk-1 [Source:UniProtKB/Swiss-Prot;Acc:Q8I4B0]) HSP 1 Score: 302.753 bits (774), Expect = 8.681e-97 Identity = 166/400 (41.50%), Postives = 253/400 (63.25%), Query Frame = 1
Query: 343 RRNALEYSSLRSGPFQYDLKEKVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTL-EVIELPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFFNKSHCVSGAA-PNFLD--------VFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVLVTFDCDGAKKSASLAF-----LRVIRLIRVFKLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHK 1497
+R + SS + P+ + V IN+SG+ F+T+ L+ +P +LLGD +KR ++ E+FFDR+R FESI YQ+GG++KRP VP +IFL E+ F+Q+ +++ + EG+ + + +P NK +R IW L E+P++S+SA +A +S+A LSI+ FC ET P + ++ +A LD FF +E +C WFTIE+ RFISCP KV F + NIID A+ P++V F D +K ++S++F LR++R+ RVFKL++HS GLQ+L TFR+S++ L + ++++++LF+S +Y+AE G P+S+ SIP +FW+ ++TM TVGYGD VP GK+VG +CA+ GVLTLA+PVPII NF FY +
Sbjct: 73 QRGTPDTSSTQGHPYTDQI---VTINVSGMRFQTFESTLSRYPNSLLGDRNKRQHFFVSDTNEFFFDRHRTTFESILYIYQSGGRVKRPEIVPIDIFLKEMRFFQMGDDLLEEFWIAEGYEKPKEVMMPNNKTQRKIWELMEYPDSSLSARIIAFISIAVIALSIISFCWETVPSDIEEKPINNSATAELLDEMDEKHYSPFFWIELMCILWFTIELILRFISCPCKVTFATSVLNIIDFVAIAPFFVNF------FFADTSKSNSSMSFAVLRVLRLVRVFRVFKLSRHSVGLQILGKTFRSSVQEFCLLIFFMAIALVLFASGMYFAEQGEPNSKFTSIPASFWFVLVTMTTVGYGDLVPLSPFGKVVGGMCAMIGVLTLALPVPIIVANFKHFYRQE 463
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Celegans
Match: shk-1 (Potassium voltage-gated channel protein shk-1 [Source:UniProtKB/Swiss-Prot;Acc:Q8I4B0]) HSP 1 Score: 302.753 bits (774), Expect = 2.588e-96 Identity = 166/401 (41.40%), Postives = 253/401 (63.09%), Query Frame = 1
Query: 343 RRNALEYSSLRSGPFQYDLKEKVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTL-EVIELPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFFNKSHCVSGAA-PNFLD--------VFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVLVTFDCDGAKKSASLAF-----LRVIRLIRVFKLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHKT 1500
+R + SS + P+ + V IN+SG+ F+T+ L+ +P +LLGD +KR ++ E+FFDR+R FESI YQ+GG++KRP VP +IFL E+ F+Q+ +++ + EG+ + + +P NK +R IW L E+P++S+SA +A +S+A LSI+ FC ET P + ++ +A LD FF +E +C WFTIE+ RFISCP KV F + NIID A+ P++V F D +K ++S++F LR++R+ RVFKL++HS GLQ+L TFR+S++ L + ++++++LF+S +Y+AE G P+S+ SIP +FW+ ++TM TVGYGD VP GK+VG +CA+ GVLTLA+PVPII NF FY +
Sbjct: 116 QRGTPDTSSTQGHPYTDQI---VTINVSGMRFQTFESTLSRYPNSLLGDRNKRQHFFVSDTNEFFFDRHRTTFESILYIYQSGGRVKRPEIVPIDIFLKEMRFFQMGDDLLEEFWIAEGYEKPKEVMMPNNKTQRKIWELMEYPDSSLSARIIAFISIAVIALSIISFCWETVPSDIEEKPINNSATAELLDEMDEKHYSPFFWIELMCILWFTIELILRFISCPCKVTFATSVLNIIDFVAIAPFFVNF------FFADTSKSNSSMSFAVLRVLRLVRVFRVFKLSRHSVGLQILGKTFRSSVQEFCLLIFFMAIALVLFASGMYFAEQGEPNSKFTSIPASFWFVLVTMTTVGYGDLVPLSPFGKVVGGMCAMIGVLTLALPVPIIVANFKHFYRQEN 507
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Fly
Match: Sh (gene:FBgn0003380 transcript:FBtr0089657) HSP 1 Score: 394.43 bits (1012), Expect = 4.441e-130 Identity = 197/452 (43.58%), Postives = 288/452 (63.72%), Query Frame = 1
Query: 232 ERAIKFKGSTPKSNSFKIIWNSFKRSLSSNDSGSEKKRRNALEYSSLRSGPFQYDLKEKVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTLEVIE-LPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFF----------NKSHCVSGAAPNFLDVFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVL-------------VTFDCDGAKKSASLAFLRVIRLIRVF---KLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHKTGR 1506
ER ++ + + NS + S + LSS D P +D E+VVIN+SGL FET LN+ P TLLGDP++R Y+D R EYFFDR RP+F++I YYQ+GG+++RPVNVP ++F E+ FY++ I+ +++DEG E LP N+ +R +W+LFE+PE+S +A VA++SV +LSIV+FC+ET P F N + P+ D FF++ET+C WFT E++ RF++CP+K+ F +D+ N+ID+ A+IPY++TL V+ V+ + ++ SLA LRVIRL+RVF KL++HS GLQ+L T +AS+ LGL + L + ++LFSS +Y+AE G+ +S +SIPDAFWWA++TM TVGYGD P + GK+VGS+CA++GVLT+A+PVP+I NFN FY +T +
Sbjct: 42 ERKLQLREQQLQRNSLDG-YGSLPK-LSSQDEEGGAGHGFGGGPQHFEPIPHDHDFCERVVINVSGLRFETQLRTLNQFPDTLLGDPARRLRYFDPLRNEYFFDRSRPSFDAILYYYQSGGRLRRPVNVPLDVFSEEIKFYELGDQAINKFREDEGFIKEEERPLPDNEKQRKVWLLFEYPESSQAARVVAIISVFVILLSIVIFCLETLPEFKHYKVFNTTTNGTKIEEDEVPDITDPFFLIETLCIIWFTFELTVRFLACPNKLNFCRDVMNVIDIIAIIPYFITLATVVAEEEDTLNLPKAPVSPQDKSSNQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGRTLKASMRELGLLIFFLFIGVVLFSSAVYFAEAGSENSFFKSIPDAFWWAVVTMTTVGYGDMTPVGVWGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETDQ 491
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Fly
Match: Sh (gene:FBgn0003380 transcript:FBtr0302903) HSP 1 Score: 392.504 bits (1007), Expect = 1.581e-129 Identity = 188/402 (46.77%), Postives = 273/402 (67.91%), Query Frame = 1
Query: 382 PFQYDLKEKVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTLEVIE-LPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFF----------NKSHCVSGAAPNFLDVFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVL-------------VTFDCDGAKKSASLAFLRVIRLIRVF---KLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHKTGR 1506
P +D E+VVIN+SGL FET LN+ P TLLGDP++R Y+D R EYFFDR RP+F++I YYQ+GG+++RPVNVP ++F E+ FY++ I+ +++DEG E LP N+ +R +W+LFE+PE+S +A VA++SV +LSIV+FC+ET P F N + P+ D FF++ET+C WFT E++ RF++CP+K+ F +D+ N+ID+ A+IPY++TL V+ V+ + ++ SLA LRVIRL+RVF KL++HS GLQ+L T +AS+ LGL + L + ++LFSS +Y+AE G+ +S +SIPDAFWWA++TM TVGYGD P + GK+VGS+CA++GVLT+A+PVP+I NFN FY +T +
Sbjct: 78 PHDHDFCERVVINVSGLRFETQLRTLNQFPDTLLGDPARRLRYFDPLRNEYFFDRSRPSFDAILYYYQSGGRLRRPVNVPLDVFSEEIKFYELGDQAINKFREDEGFIKEEERPLPDNEKQRKVWLLFEYPESSQAARVVAIISVFVILLSIVIFCLETLPEFKHYKVFNTTTNGTKIEEDEVPDITDPFFLIETLCIIWFTFELTVRFLACPNKLNFCRDVMNVIDIIAIIPYFITLATVVAEEEDTLNLPKAPVSPQDKSSNQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGRTLKASMRELGLLIFFLFIGVVLFSSAVYFAEAGSENSFFKSIPDAFWWAVVTMTTVGYGDMTPVGVWGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETDQ 479
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Fly
Match: Sh (gene:FBgn0003380 transcript:FBtr0089661) HSP 1 Score: 392.504 bits (1007), Expect = 1.581e-129 Identity = 188/402 (46.77%), Postives = 273/402 (67.91%), Query Frame = 1
Query: 382 PFQYDLKEKVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTLEVIE-LPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFF----------NKSHCVSGAAPNFLDVFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVL-------------VTFDCDGAKKSASLAFLRVIRLIRVF---KLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHKTGR 1506
P +D E+VVIN+SGL FET LN+ P TLLGDP++R Y+D R EYFFDR RP+F++I YYQ+GG+++RPVNVP ++F E+ FY++ I+ +++DEG E LP N+ +R +W+LFE+PE+S +A VA++SV +LSIV+FC+ET P F N + P+ D FF++ET+C WFT E++ RF++CP+K+ F +D+ N+ID+ A+IPY++TL V+ V+ + ++ SLA LRVIRL+RVF KL++HS GLQ+L T +AS+ LGL + L + ++LFSS +Y+AE G+ +S +SIPDAFWWA++TM TVGYGD P + GK+VGS+CA++GVLT+A+PVP+I NFN FY +T +
Sbjct: 78 PHDHDFCERVVINVSGLRFETQLRTLNQFPDTLLGDPARRLRYFDPLRNEYFFDRSRPSFDAILYYYQSGGRLRRPVNVPLDVFSEEIKFYELGDQAINKFREDEGFIKEEERPLPDNEKQRKVWLLFEYPESSQAARVVAIISVFVILLSIVIFCLETLPEFKHYKVFNTTTNGTKIEEDEVPDITDPFFLIETLCIIWFTFELTVRFLACPNKLNFCRDVMNVIDIIAIIPYFITLATVVAEEEDTLNLPKAPVSPQDKSSNQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGRTLKASMRELGLLIFFLFIGVVLFSSAVYFAEAGSENSFFKSIPDAFWWAVVTMTTVGYGDMTPVGVWGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETDQ 479
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Fly
Match: Sh (gene:FBgn0003380 transcript:FBtr0302902) HSP 1 Score: 392.504 bits (1007), Expect = 1.581e-129 Identity = 188/402 (46.77%), Postives = 273/402 (67.91%), Query Frame = 1
Query: 382 PFQYDLKEKVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTLEVIE-LPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFF----------NKSHCVSGAAPNFLDVFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVL-------------VTFDCDGAKKSASLAFLRVIRLIRVF---KLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHKTGR 1506
P +D E+VVIN+SGL FET LN+ P TLLGDP++R Y+D R EYFFDR RP+F++I YYQ+GG+++RPVNVP ++F E+ FY++ I+ +++DEG E LP N+ +R +W+LFE+PE+S +A VA++SV +LSIV+FC+ET P F N + P+ D FF++ET+C WFT E++ RF++CP+K+ F +D+ N+ID+ A+IPY++TL V+ V+ + ++ SLA LRVIRL+RVF KL++HS GLQ+L T +AS+ LGL + L + ++LFSS +Y+AE G+ +S +SIPDAFWWA++TM TVGYGD P + GK+VGS+CA++GVLT+A+PVP+I NFN FY +T +
Sbjct: 78 PHDHDFCERVVINVSGLRFETQLRTLNQFPDTLLGDPARRLRYFDPLRNEYFFDRSRPSFDAILYYYQSGGRLRRPVNVPLDVFSEEIKFYELGDQAINKFREDEGFIKEEERPLPDNEKQRKVWLLFEYPESSQAARVVAIISVFVILLSIVIFCLETLPEFKHYKVFNTTTNGTKIEEDEVPDITDPFFLIETLCIIWFTFELTVRFLACPNKLNFCRDVMNVIDIIAIIPYFITLATVVAEEEDTLNLPKAPVSPQDKSSNQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGRTLKASMRELGLLIFFLFIGVVLFSSAVYFAEAGSENSFFKSIPDAFWWAVVTMTTVGYGDMTPVGVWGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETDQ 479
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Fly
Match: Sh (gene:FBgn0003380 transcript:FBtr0308200) HSP 1 Score: 392.504 bits (1007), Expect = 1.754e-129 Identity = 188/402 (46.77%), Postives = 273/402 (67.91%), Query Frame = 1
Query: 382 PFQYDLKEKVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTLEVIE-LPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFF----------NKSHCVSGAAPNFLDVFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVL-------------VTFDCDGAKKSASLAFLRVIRLIRVF---KLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHKTGR 1506
P +D E+VVIN+SGL FET LN+ P TLLGDP++R Y+D R EYFFDR RP+F++I YYQ+GG+++RPVNVP ++F E+ FY++ I+ +++DEG E LP N+ +R +W+LFE+PE+S +A VA++SV +LSIV+FC+ET P F N + P+ D FF++ET+C WFT E++ RF++CP+K+ F +D+ N+ID+ A+IPY++TL V+ V+ + ++ SLA LRVIRL+RVF KL++HS GLQ+L T +AS+ LGL + L + ++LFSS +Y+AE G+ +S +SIPDAFWWA++TM TVGYGD P + GK+VGS+CA++GVLT+A+PVP+I NFN FY +T +
Sbjct: 78 PHDHDFCERVVINVSGLRFETQLRTLNQFPDTLLGDPARRLRYFDPLRNEYFFDRSRPSFDAILYYYQSGGRLRRPVNVPLDVFSEEIKFYELGDQAINKFREDEGFIKEEERPLPDNEKQRKVWLLFEYPESSQAARVVAIISVFVILLSIVIFCLETLPEFKHYKVFNTTTNGTKIEEDEVPDITDPFFLIETLCIIWFTFELTVRFLACPNKLNFCRDVMNVIDIIAIIPYFITLATVVAEEEDTLNLPKAPVSPQDKSSNQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGRTLKASMRELGLLIFFLFIGVVLFSSAVYFAEAGSENSFFKSIPDAFWWAVVTMTTVGYGDMTPVGVWGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETDQ 479
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Zebrafish
Match: kcna2b (potassium voltage-gated channel, shaker-related subfamily, member 2b [Source:ZFIN;Acc:ZDB-GENE-080204-89]) HSP 1 Score: 389.423 bits (999), Expect = 3.591e-130 Identity = 193/385 (50.13%), Postives = 263/385 (68.31%), Query Frame = 1
Query: 403 EKVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTLEVIEL-PTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFF-------------NKSHCVSGAAPNFLDVFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVLVTFDCDG--AKKSASLAFLRVIRLIRVF---KLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHKT 1500
E+VVINISGL FET L++ P TLLGDP KR Y+D R EYFFDR RP+F++I YYQ+GG+++RPVNV +IF E+ FY++ + I+ +++DEG E +L P N+ +R +W+LFE+PE+S A +A++SV ++SIV FC+ET P F + + +S + F D FFILET+C WF+ E RF +CPSK F +I NIID+ A+IPY++TL L DG +++ SLA LRVIRL+RVF KL++HS GLQ+L T +AS+ LGL + L + +ILFSS +Y+AE PDSQ SIPDAFWWA+++M TVGYGD VP I GK+VGS+CA++GVLT+A+PVP+I NFN FY +T
Sbjct: 33 ERVVINISGLRFETQLKTLSQFPETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVTLDIFSEEIRFYELGEEAIEMFREDEGFIKEEEKLLPENEFQRQVWLLFEYPESSGPARIIAIISVMVILISIVSFCLETLPVFRNEETDMHKAYRTDSNSTISYTSTYFTDPFFILETLCIIWFSFEFLVRFFACPSKAGFFVNIMNIIDIVAIIPYFITLGTELAEKAEDGQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADEPDSQFVSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRET 417
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Zebrafish
Match: kcna2a (potassium voltage-gated channel, shaker-related subfamily, member 2a [Source:ZFIN;Acc:ZDB-GENE-131113-1]) HSP 1 Score: 380.563 bits (976), Expect = 1.279e-126 Identity = 190/385 (49.35%), Postives = 257/385 (66.75%), Query Frame = 1
Query: 403 EKVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTLEVIE-LPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFFNKSHCVSGAAP-------------NFLDVFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVLVTFDCDG--AKKSASLAFLRVIRLIRVF---KLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHKT 1500
E+VVINISGL FET L++ P TLLGDP KR Y+D R EYFFDR RP+F++I YYQ+GG+++RPVNV ++F E+ FY++ I+ +++DEG E LP N+ ++ +W+LFE+PE+S A +A++SV ++SIV FC+ET P F P F D FFILET+C WF+ E RF +CPSK F +I N+IDV A+IPY++TL L DG +++ SLA LRVIRL+RVF KL++HS GLQ+L T +AS+ LGL + L + +ILFSS +Y+AE P+SQ SIPDAFWWA+++M TVGYGD VP I GK+VGS+CA++GVLT+A+PVP+I NFN FY +T
Sbjct: 32 ERVVINISGLRFETQLKTLSQFPETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVTLDVFSEEIRFYELGDEAIEIFREDEGFIKEEERPLPDNEFQKQVWLLFEYPESSGPARIIAIISVMVILISIVSFCLETLPIFRSDEEEMHKVPVNVNNSTTSYTSTYFTDPFFILETLCIIWFSFEFLVRFFACPSKASFFVNIMNMIDVVAIIPYFITLGTELAEKAEDGQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADEPESQFYSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRET 416
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Zebrafish
Match: kcna2a (potassium voltage-gated channel, shaker-related subfamily, member 2a [Source:ZFIN;Acc:ZDB-GENE-131113-1]) HSP 1 Score: 380.563 bits (976), Expect = 1.279e-126 Identity = 190/385 (49.35%), Postives = 257/385 (66.75%), Query Frame = 1
Query: 403 EKVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTLEVIE-LPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFFNKSHCVSGAAP-------------NFLDVFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVLVTFDCDG--AKKSASLAFLRVIRLIRVF---KLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHKT 1500
E+VVINISGL FET L++ P TLLGDP KR Y+D R EYFFDR RP+F++I YYQ+GG+++RPVNV ++F E+ FY++ I+ +++DEG E LP N+ ++ +W+LFE+PE+S A +A++SV ++SIV FC+ET P F P F D FFILET+C WF+ E RF +CPSK F +I N+IDV A+IPY++TL L DG +++ SLA LRVIRL+RVF KL++HS GLQ+L T +AS+ LGL + L + +ILFSS +Y+AE P+SQ SIPDAFWWA+++M TVGYGD VP I GK+VGS+CA++GVLT+A+PVP+I NFN FY +T
Sbjct: 32 ERVVINISGLRFETQLKTLSQFPETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVTLDVFSEEIRFYELGDEAIEIFREDEGFIKEEERPLPDNEFQKQVWLLFEYPESSGPARIIAIISVMVILISIVSFCLETLPIFRSDEEEMHKVPVNVNNSTTSYTSTYFTDPFFILETLCIIWFSFEFLVRFFACPSKASFFVNIMNMIDVVAIIPYFITLGTELAEKAEDGQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADEPESQFYSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRET 416
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Zebrafish
Match: CABZ01113981.1 (pep scaffold:GRCz11:KN150008.1:12653:14179:-1 gene:ENSDARG00000102982.2 transcript:ENSDART00000162692.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CABZ01113981.1) HSP 1 Score: 377.481 bits (968), Expect = 7.596e-126 Identity = 189/374 (50.53%), Postives = 260/374 (69.52%), Query Frame = 1
Query: 403 EKVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTLEVIE-LPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLF---CVETHPFFNKSHCVSGAAPN-FLDVFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVLVTFDCDGAKKSASLAFLRVIRLIRVF---KLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHKT 1500
E+VVINISGL FET L + P TLLGDP KR ++D R EYFFDR RP+F++I YYQ+GG+++RPVNVP +IF+ E+ FY++ + VI+ +K+DEG E LP ++ +R +W+LFE+PE+S A +A++SV ++SI E HP N + S PN F D FFI+ET+C WF+ E+ RF++CPSK F K+I N ID+ A+IPY++TL L +G +++ SLA LRVIRL+RVF KL++HS GLQ+L T +AS+ LGL + L + +ILFSS +Y+AE +PDS SIPDAFWWA+++M TVGYGD P I GK+VGS+CA++GVLT+A+PVP+I NFN FY +T
Sbjct: 34 ERVVINISGLRFETQLKTLAQFPATLLGDPRKRMRFFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPVDIFMEEIKFYELGEEVIENFKEDEGFIKEEERPLPESEFQRQVWLLFEYPESSGPARGIAIVSVLVILISIFREDGKAFEEHPGVNGT-AASVKKPNPFTDPFFIVETLCIIWFSFELLVRFLACPSKPAFFKNIMNTIDIVAIIPYFITLGLELAEHQGNG-QQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAETDDPDSGFSSIPDAFWWAVVSMTTVGYGDMCPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRET 405
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Zebrafish
Match: kcna1a (potassium voltage-gated channel, shaker-related subfamily, member 1a [Source:ZFIN;Acc:ZDB-GENE-110408-15]) HSP 1 Score: 366.311 bits (939), Expect = 4.551e-121 Identity = 188/404 (46.53%), Postives = 266/404 (65.84%), Query Frame = 1
Query: 391 YDLKEKVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTLEVIE-LPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFFNK---------SHCVSGAAPNFL-DVFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVLVTFDCDG----AKKSASLAFLRVIRLIRVF---KLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHKTGRLRF*ILINVTMINI 1548
++ E+VVINI+GL FET L + P TLLG+P KR Y+D R EYFFDR RP+F++I YYQ+GG+++RP NVP ++F E+ FY++ ++ +++DEG E LP + +R IW+LFE PE+S A +A++SV ++SIV+FC+ET P + + P+ L D FFI+ET+C WF+ E+ RF +CPSK F K++ N ID+ A+IPY++TL L + DG +++ SLA LRVIRL+RVF KL++HS GLQ+L T +AS+ LGL + L + +ILFSS +Y+AE +S SIPDAFWWA+++M TVGYGD VP I GK+VGS+CA++GVLT+A+PVP+I NFN FY +T L+NV+ NI
Sbjct: 30 HECCERVVINIAGLRFETQLKTLAQFPETLLGNPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPANVPLDMFSEEIKFYELGVEAMEKFREDEGFIREEERPLPEKEFQRQIWLLFEHPESSGPARGIAIVSVMVILISIVIFCLETLPELKEDPEGRIKIIGNTTYYYKPSILADPFFIIETLCIIWFSFELIVRFFACPSKAAFFKNMMNTIDIVAIIPYFITLGTELAE-EQDGKEGKGEQATSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEAEEKESYFSSIPDAFWWAVVSMTTVGYGDMVPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQAQLLNVSNPNI 432
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Xenopus
Match: KCNA3 (potassium voltage-gated channel subfamily A member 3 [Source:HGNC Symbol;Acc:HGNC:6221]) HSP 1 Score: 390.193 bits (1001), Expect = 1.929e-130 Identity = 197/403 (48.88%), Postives = 272/403 (67.49%), Query Frame = 1
Query: 340 KRRNALEYSSLRSGPFQYDLKEKVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTLEVIE-LPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFFNKSHCVSGAA------------PNFLDVFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVLVTFDCDGAKKSASLAFLRVIRLIRVF---KLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHKT 1500
++R +L SS R ++ E+VVINISGL FET L + P TLLGDP KR Y+D R EYFFDR RP+F++I YYQ+GG+I+RPVNVP +IF E+ FY++ + ++ +++DEG E LP N+ +R +W+LFE+PE+S A +A++SV ++SIV+FC+ET P F SG A +F D FF++ET+C WF+ E+ RF +CPSK F K+I NIID+ A+IPY++TL L +G +++ SLA LRVIRL+RVF KL++HS GLQ+L T +AS+ LGL + L + +ILFSS +Y+AE +P S SIPDAFWWA++TM TVGYGD P I GK+VGS+CA++GVLT+A+PVP+I NFN FY +T
Sbjct: 3 EKRLSLCLSSHRQE--DHECCERVVINISGLRFETQLKTLAQFPDTLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRIRRPVNVPIDIFSEEIRFYELGEEAMEKFREDEGFIREEERPLPPNEFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPEFRDDKEYSGTALPPGNGTGPYISSSFTDPFFVVETLCIIWFSFELLVRFFACPSKATFCKNIMNIIDIVAIIPYFITLGTELAERQGNG-QQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADDPSSGFNSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRET 402
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Xenopus
Match: KCNA2 (potassium channel, voltage gated shaker related subfamily A, member 3 [Source:NCBI gene;Acc:100496794]) HSP 1 Score: 384.03 bits (985), Expect = 9.781e-128 Identity = 191/393 (48.60%), Postives = 266/393 (67.68%), Query Frame = 1
Query: 391 YDLKEKVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTLEVIE-LPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFF-NKSHCVSGAAPN----------------FLDVFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVLV--TFDCDGAKKSASLAFLRVIRLIRVF---KLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHKT 1500
++ E+VVINISGL FET L++ P TLLGDP KR Y+D R EYFFDR RP+F++I YYQ+GG+++RPVNVP +IF E+ FY++ + ++ +++DEG E LP N+ ++ +W+LFE+PE+S A +A++SV ++SIV FC+ET P F +++ + G+ N F D FFI+ET+C WF+ E RF +CPSK F +I NIID+ A+IPY++TL L T D +++ SLA LRVIRL+RVF KL++HS GLQ+L T +AS+ LGL + L + +ILFSS +Y+AE DSQ SIPDAFWWA+++M TVGYGD VP I GK+VGS+CA++GVLT+A+PVP+I NFN FY +T
Sbjct: 29 HECCERVVINISGLRFETQLKTLSQFPETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFYELGEEAMEIFREDEGFIKEEERPLPDNEYQKQVWLLFEYPESSGPARIIAIISVMVILISIVSFCLETLPVFRDENEDMHGSGVNYYPYSNSTVRYQKSNTFTDPFFIVETLCIIWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEKTEDGQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADERDSQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRET 421
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Xenopus
Match: KCNA5 (potassium channel, voltage gated shaker related subfamily A, member 5 [Source:NCBI gene;Acc:496997]) HSP 1 Score: 386.341 bits (991), Expect = 5.726e-127 Identity = 185/392 (47.19%), Postives = 262/392 (66.84%), Query Frame = 1
Query: 379 GPFQYDLKEKVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTL-EVIELPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFFNKSHCVSGAAPNFL--------------DVFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVLVTFDCDGAKKSASLAFLRVIRLIRVF---KLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHKT 1500
G ++ ++V+INI+GL FET LN+ P TLLGDP KR ++D R EYFFDR RP+F+ I +YQ+GGKI+RPVNV ++F E+ FY++ + ++ +++DEG E LP N+ +R +W++FE+PE+S SA +A++SV ++SI+ FC+ET P F + + A L D FFI+ET C WFT E+ RF +CPSK F K+I NIID+ A+IPY++TL L + +++ SLA LRVIRL+RVF KL++HS GLQ+L T +AS+ LGL + L + +ILFSS +Y+AE +P+S SIPDAFWWA++TM TVGYGD P + GK+VGS+CA++GVLT+A+PVP+I NFN FY +T
Sbjct: 161 GIMDHESNQRVIINIAGLRFETQLSTLNQFPDTLLGDPEKRMRFFDPLRNEYFFDRNRPSFDGILYFYQSGGKIRRPVNVSIDVFADEIRFYELGEEAMERFREDEGFIKDEEKPLPCNEFQRQVWLIFEYPESSSSARGIAIVSVLVILISIITFCLETLPEFRDENELPPALSKVLNDTQEHPSPPSGLTDPFFIIETTCVIWFTFELLVRFFACPSKSDFSKNIMNIIDIVAIIPYFITLGTELAQHQTNNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADDPESHFSSIPDAFWWAVVTMTTVGYGDMRPVTVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRET 552
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Xenopus
Match: ENSXETT00000049277.1 (potassium channel, voltage gated shaker related subfamily A, member 6 [Source:NCBI gene;Acc:100492986]) HSP 1 Score: 380.178 bits (975), Expect = 8.627e-127 Identity = 190/384 (49.48%), Postives = 262/384 (68.23%), Query Frame = 1
Query: 394 DLKEKVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTLEVIE-LPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFFNKSHCVSGAAPN-----------FLDVFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVLVTFDCDGAKKSASLAFLRVIRLIRVF---KLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHKT 1500
D E+VVINISGL FET L++ P TLLGDP KR ++D R EYFFDR RP+F++I YYQ+GG+++RPVNVP +IFL E+ FY++ + VI+ ++ DEG E LP N +R +W+LFE+PE+S A +A++SV ++SIV+FC+ET P F + SG P F D FF+ ET+C WF+ E+ RF +CPSK F K++ N+ID+ A+IPY++TL L +++ SLA LRVIRL+RVF KL++HS GLQ+L T +AS+ LGL + L + +ILFSS +Y+AE +P+S SIPDAFWWA+++M TVGYGD P I GK+VGS+CA++GVLT+A+PVP+I NFN FY +T
Sbjct: 11 DCCERVVINISGLRFETQLRTLSQFPQTLLGDPRKRMRFFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPVDIFLEEIKFYELGEEVIEIFRDDEGFIKEEERPLPENDFQRQVWLLFEYPESSGPARGIAIVSVLIILISIVIFCLETLPEFREEARQSGGQPAVNGTHTFTNSPFTDPFFLTETLCIIWFSFELLVRFFACPSKPAFFKNMMNVIDIVAIIPYFITLGTELAEQQGSNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAETDDPESLFTSIPDAFWWAVVSMTTVGYGDMYPMTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRET 394
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Xenopus
Match: fastkd3 (FAST kinase domains 3 [Source:Xenbase;Acc:XB-GENE-5998409]) HSP 1 Score: 372.474 bits (955), Expect = 3.122e-124 Identity = 185/379 (48.81%), Postives = 258/379 (68.07%), Query Frame = 1
Query: 403 EKVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTLEVIEL-PTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFFNKSHCVS------GAAPN---FLDVFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVLVTFDCDGAKKSASLAFLRVIRLIRVF---KLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHKT 1500
E+VVIN+SGL FET L+ P TLLGDP +R ++D R EYFFDR RP F+SI +YQ+GG+++RP NVP ++F+ EL FYQ+ +VI +++DEG E L P + + +W+LFE P++S +A +A++SV ++SIV+FC+ET P F +S P F D FFI+ET+C WF+ E+S RFI+CPSK F KDI N+ID A+IPY+V L L G + + SLA LRVIRL+RVF KL++HS GLQ+L T +AS+ LGL + L + +ILFSS +Y+AE + D++ SIP+AFWWA++TM TVGYGD P+ + GKLVGS+CA++GVLT+++PVP+I NF+ FY +T
Sbjct: 8 ERVVINVSGLRFETQIRTLHRFPDTLLGDPRRRIHFFDPLRNEYFFDRNRPCFDSILYFYQSGGRLRRPTNVPLDVFMEELLFYQLGDNVIRKFREDEGFMKEEERLLPECEFMKQVWLLFEHPDSSSAARIIAIISVMVILISIVIFCLETLPEFRDDRDLSLPKDPLSGRPQKSPFEDPFFIVETICICWFSFELSVRFIACPSKAAFFKDIMNMIDFVAIIPYFVALGTELARHKGVG-QPAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADHEDTKFTSIPEAFWWAVVTMTTVGYGDMSPETVGGKLVGSLCAIAGVLTISLPVPVIVSNFSYFYHRET 385
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Mouse
Match: Kcna2 (potassium voltage-gated channel, shaker-related subfamily, member 2 [Source:MGI Symbol;Acc:MGI:96659]) HSP 1 Score: 384.8 bits (987), Expect = 3.748e-128 Identity = 191/393 (48.60%), Postives = 263/393 (66.92%), Query Frame = 1
Query: 391 YDLKEKVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTLEVIE-LPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFFNKS-----------HCVSGA------APNFLDVFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVLVT--FDCDGAKKSASLAFLRVIRLIRVF---KLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHKT 1500
++ E+VVINISGL FET L + P TLLGDP KR Y+D R EYFFDR RP+F++I YYQ+GG+++RPVNVP +IF E+ FY++ + ++ +++DEG+ E LP N+ +R +W+LFE+PE+S A +A++SV ++SIV FC+ET P F H S + + +F D FFI+ET+C WF+ E RF +CPSK F +I NIID+ A+IPY++TL L D +++ SLA LRVIRL+RVF KL++HS GLQ+L T +AS+ LGL + L + +ILFSS +Y+AE DSQ SIPDAFWWA+++M TVGYGD VP I GK+VGS+CA++GVLT+A+PVP+I NFN FY +T
Sbjct: 29 HECCERVVINISGLRFETQLKTLAQFPETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFYELGEEAMEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPARIIAIVSVMVILISIVSFCLETLPIFRDENEDMHGGGVTFHTYSNSTIGYQQSTSFTDPFFIVETLCIIWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEKPEDAQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADERDSQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRET 421
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Mouse
Match: Kcna2 (potassium voltage-gated channel, shaker-related subfamily, member 2 [Source:MGI Symbol;Acc:MGI:96659]) HSP 1 Score: 384.8 bits (987), Expect = 3.748e-128 Identity = 191/393 (48.60%), Postives = 263/393 (66.92%), Query Frame = 1
Query: 391 YDLKEKVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTLEVIE-LPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFFNKS-----------HCVSGA------APNFLDVFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVLVT--FDCDGAKKSASLAFLRVIRLIRVF---KLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHKT 1500
++ E+VVINISGL FET L + P TLLGDP KR Y+D R EYFFDR RP+F++I YYQ+GG+++RPVNVP +IF E+ FY++ + ++ +++DEG+ E LP N+ +R +W+LFE+PE+S A +A++SV ++SIV FC+ET P F H S + + +F D FFI+ET+C WF+ E RF +CPSK F +I NIID+ A+IPY++TL L D +++ SLA LRVIRL+RVF KL++HS GLQ+L T +AS+ LGL + L + +ILFSS +Y+AE DSQ SIPDAFWWA+++M TVGYGD VP I GK+VGS+CA++GVLT+A+PVP+I NFN FY +T
Sbjct: 29 HECCERVVINISGLRFETQLKTLAQFPETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFYELGEEAMEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPARIIAIVSVMVILISIVSFCLETLPIFRDENEDMHGGGVTFHTYSNSTIGYQQSTSFTDPFFIVETLCIIWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEKPEDAQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADERDSQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRET 421
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Mouse
Match: Kcna2 (potassium voltage-gated channel, shaker-related subfamily, member 2 [Source:MGI Symbol;Acc:MGI:96659]) HSP 1 Score: 384.8 bits (987), Expect = 3.748e-128 Identity = 191/393 (48.60%), Postives = 263/393 (66.92%), Query Frame = 1
Query: 391 YDLKEKVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTLEVIE-LPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFFNKS-----------HCVSGA------APNFLDVFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVLVT--FDCDGAKKSASLAFLRVIRLIRVF---KLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHKT 1500
++ E+VVINISGL FET L + P TLLGDP KR Y+D R EYFFDR RP+F++I YYQ+GG+++RPVNVP +IF E+ FY++ + ++ +++DEG+ E LP N+ +R +W+LFE+PE+S A +A++SV ++SIV FC+ET P F H S + + +F D FFI+ET+C WF+ E RF +CPSK F +I NIID+ A+IPY++TL L D +++ SLA LRVIRL+RVF KL++HS GLQ+L T +AS+ LGL + L + +ILFSS +Y+AE DSQ SIPDAFWWA+++M TVGYGD VP I GK+VGS+CA++GVLT+A+PVP+I NFN FY +T
Sbjct: 29 HECCERVVINISGLRFETQLKTLAQFPETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFYELGEEAMEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPARIIAIVSVMVILISIVSFCLETLPIFRDENEDMHGGGVTFHTYSNSTIGYQQSTSFTDPFFIVETLCIIWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEKPEDAQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADERDSQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRET 421
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Mouse
Match: Kcna3 (potassium voltage-gated channel, shaker-related subfamily, member 3 [Source:MGI Symbol;Acc:MGI:96660]) HSP 1 Score: 382.104 bits (980), Expect = 9.057e-127 Identity = 188/389 (48.33%), Postives = 260/389 (66.84%), Query Frame = 1
Query: 403 EKVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTLEVIE-LPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFF-------------------NKSHCVSGAAPNFLDVFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVLVTFDCDGAKKSASLAFLRVIRLIRVF---KLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHKT 1500
E+VVINISGL FET L + P TLLGDP +R Y+D R EYFFDR RP+F++I YYQ+GG+I+RPVNVP +IF E+ FYQ+ + ++ +++DEG E LP +R +W+LFE+PE+S A +A++SV ++SIV+FC+ET P F N + A +F D FF++ET+C WF+ E+ RF +CPSK F ++I N+ID+ A+IPY++TL L +G +++ SLA LRVIRL+RVF KL++HS GLQ+L T +AS+ LGL + L + +ILFSS +Y+AE +P S SIPDAFWWA++TM TVGYGD P I GK+VGS+CA++GVLT+A+PVP+I NFN FY +T
Sbjct: 57 ERVVINISGLRFETQLKTLCQFPETLLGDPKRRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRIRRPVNVPIDIFSEEIRFYQLGEEAMEKFREDEGFLREEERPLPRRDFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPEFRDEKDYPASPSQDVFEAANNSTSGAPSGASSFSDPFFVVETLCIIWFSFELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITLGTELAERQGNG-QQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADDPSSGFNSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRET 444
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Mouse
Match: Kcna1 (potassium voltage-gated channel, shaker-related subfamily, member 1 [Source:MGI Symbol;Acc:MGI:96654]) HSP 1 Score: 372.089 bits (954), Expect = 2.656e-123 Identity = 182/387 (47.03%), Postives = 257/387 (66.41%), Query Frame = 1
Query: 391 YDLKEKVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTLEVIE-LPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFFNKSHCVSGAAPN------------FLDVFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTL-TNVLVTFDCDGAKKSASLAFLRVIRLIRVF---KLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHKT 1500
++ E+VVINISGL FET L + P TLLG+P KR Y+D R EYFFDR RP+F++I YYQ+GG+++RPVNVP ++F E+ FY++ + ++ +++DEG E LP + +R +W+LFE+PE+S A +A++SV ++SIV+FC+ET P +G F D FFI+ET+C WF+ E+ RF +CPSK F K+I N ID+ A+IPY++TL T + +++ SLA LRVIRL+RVF KL++HS GLQ+L T +AS+ LGL + L + +ILFSS +Y+AE +S SIPDAFWWA+++M TVGYGD P I GK+VGS+CA++GVLT+A+PVP+I NFN FY +T
Sbjct: 33 HECCERVVINISGLRFETQLKTLAQFPNTLLGNPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDMFSEEIKFYELGEEAMEKFREDEGFIKEEERPLPEKEYQRQVWLLFEYPESSGPARVIAIVSVMVILISIVIFCLETLPELKDDKDFTGTIHRIDNTTVIYTSNIFTDPFFIVETLCIIWFSFELVVRFFACPSKTDFFKNIMNFIDIVAIIPYFITLGTEIAEQEGNQKGEQATSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEAEEAESHFSSIPDAFWWAVVSMTTVGYGDMYPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRET 419
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. UniProt/SwissProt
Match: sp|P08510|KCNAS_DROME (Potassium voltage-gated channel protein Shaker OS=Drosophila melanogaster OX=7227 GN=Sh PE=1 SV=3) HSP 1 Score: 394.43 bits (1012), Expect = 4.452e-129 Identity = 197/452 (43.58%), Postives = 288/452 (63.72%), Query Frame = 1
Query: 232 ERAIKFKGSTPKSNSFKIIWNSFKRSLSSNDSGSEKKRRNALEYSSLRSGPFQYDLKEKVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTLEVIE-LPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFF----------NKSHCVSGAAPNFLDVFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVL-------------VTFDCDGAKKSASLAFLRVIRLIRVF---KLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHKTGR 1506
ER ++ + + NS + S + LSS D P +D E+VVIN+SGL FET LN+ P TLLGDP++R Y+D R EYFFDR RP+F++I YYQ+GG+++RPVNVP ++F E+ FY++ I+ +++DEG E LP N+ +R +W+LFE+PE+S +A VA++SV +LSIV+FC+ET P F N + P+ D FF++ET+C WFT E++ RF++CP+K+ F +D+ N+ID+ A+IPY++TL V+ V+ + ++ SLA LRVIRL+RVF KL++HS GLQ+L T +AS+ LGL + L + ++LFSS +Y+AE G+ +S +SIPDAFWWA++TM TVGYGD P + GK+VGS+CA++GVLT+A+PVP+I NFN FY +T +
Sbjct: 42 ERKLQLREQQLQRNSLDG-YGSLPK-LSSQDEEGGAGHGFGGGPQHFEPIPHDHDFCERVVINVSGLRFETQLRTLNQFPDTLLGDPARRLRYFDPLRNEYFFDRSRPSFDAILYYYQSGGRLRRPVNVPLDVFSEEIKFYELGDQAINKFREDEGFIKEEERPLPDNEKQRKVWLLFEYPESSQAARVVAIISVFVILLSIVIFCLETLPEFKHYKVFNTTTNGTKIEEDEVPDITDPFFLIETLCIIWFTFELTVRFLACPNKLNFCRDVMNVIDIIAIIPYFITLATVVAEEEDTLNLPKAPVSPQDKSSNQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGRTLKASMRELGLLIFFLFIGVVLFSSAVYFAEAGSENSFFKSIPDAFWWAVVTMTTVGYGDMTPVGVWGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETDQ 491
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. UniProt/SwissProt
Match: sp|Q09081|KCNA2_RABIT (Potassium voltage-gated channel subfamily A member 2 OS=Oryctolagus cuniculus OX=9986 GN=KCNA2 PE=1 SV=2) HSP 1 Score: 385.571 bits (989), Expect = 1.116e-127 Identity = 192/393 (48.85%), Postives = 264/393 (67.18%), Query Frame = 1
Query: 391 YDLKEKVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTLEVIE-LPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFF---NKSHCVSG--------------AAPNFLDVFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVLVT--FDCDGAKKSASLAFLRVIRLIRVF---KLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHKT 1500
++ E+VVINISGL FET L + P TLLGDP KR Y+D R EYFFDR RP+F++I YYQ+GG+++RPVNVP +IF E+ FY++ + ++ +++DEG+ E LP N+ +R +W+LFE+PE+S A +A++SV ++SIV FC+ET P F N+ SG + +F D FFI+ET+C WF+ E RF +CPSK F +I NIID+ A+IPY++TL L D +++ SLA LRVIRL+RVF KL++HS GLQ+L T +AS+ LGL + L + +ILFSS +Y+AE DSQ SIPDAFWWA+++M TVGYGD VP I GK+VGS+CA++GVLT+A+PVP+I NFN FY +T
Sbjct: 29 HECCERVVINISGLRFETQLKTLAQFPETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFYELGEEAMEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPARIIAIVSVMVILISIVSFCLETLPIFRDENEDMHGSGMTFHTYSNSTAGYQQSTSFTDPFFIVETLCIIWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEKPEDAQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADERDSQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRET 421
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. UniProt/SwissProt
Match: sp|P63142|KCNA2_RAT (Potassium voltage-gated channel subfamily A member 2 OS=Rattus norvegicus OX=10116 GN=Kcna2 PE=1 SV=1) HSP 1 Score: 384.8 bits (987), Expect = 2.622e-127 Identity = 191/393 (48.60%), Postives = 263/393 (66.92%), Query Frame = 1
Query: 391 YDLKEKVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTLEVIE-LPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFFNKS-----------HCVSGA------APNFLDVFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVLVT--FDCDGAKKSASLAFLRVIRLIRVF---KLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHKT 1500
++ E+VVINISGL FET L + P TLLGDP KR Y+D R EYFFDR RP+F++I YYQ+GG+++RPVNVP +IF E+ FY++ + ++ +++DEG+ E LP N+ +R +W+LFE+PE+S A +A++SV ++SIV FC+ET P F H S + + +F D FFI+ET+C WF+ E RF +CPSK F +I NIID+ A+IPY++TL L D +++ SLA LRVIRL+RVF KL++HS GLQ+L T +AS+ LGL + L + +ILFSS +Y+AE DSQ SIPDAFWWA+++M TVGYGD VP I GK+VGS+CA++GVLT+A+PVP+I NFN FY +T
Sbjct: 29 HECCERVVINISGLRFETQLKTLAQFPETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFYELGEEAMEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPARIIAIVSVMVILISIVSFCLETLPIFRDENEDMHGGGVTFHTYSNSTIGYQQSTSFTDPFFIVETLCIIWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEKPEDAQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADERDSQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRET 421
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. UniProt/SwissProt
Match: sp|P63141|KCNA2_MOUSE (Potassium voltage-gated channel subfamily A member 2 OS=Mus musculus OX=10090 GN=Kcna2 PE=1 SV=1) HSP 1 Score: 384.8 bits (987), Expect = 2.622e-127 Identity = 191/393 (48.60%), Postives = 263/393 (66.92%), Query Frame = 1
Query: 391 YDLKEKVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTLEVIE-LPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFFNKS-----------HCVSGA------APNFLDVFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVLVT--FDCDGAKKSASLAFLRVIRLIRVF---KLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHKT 1500
++ E+VVINISGL FET L + P TLLGDP KR Y+D R EYFFDR RP+F++I YYQ+GG+++RPVNVP +IF E+ FY++ + ++ +++DEG+ E LP N+ +R +W+LFE+PE+S A +A++SV ++SIV FC+ET P F H S + + +F D FFI+ET+C WF+ E RF +CPSK F +I NIID+ A+IPY++TL L D +++ SLA LRVIRL+RVF KL++HS GLQ+L T +AS+ LGL + L + +ILFSS +Y+AE DSQ SIPDAFWWA+++M TVGYGD VP I GK+VGS+CA++GVLT+A+PVP+I NFN FY +T
Sbjct: 29 HECCERVVINISGLRFETQLKTLAQFPETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFYELGEEAMEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPARIIAIVSVMVILISIVSFCLETLPIFRDENEDMHGGGVTFHTYSNSTIGYQQSTSFTDPFFIVETLCIIWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEKPEDAQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADERDSQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRET 421
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. UniProt/SwissProt
Match: sp|P16389|KCNA2_HUMAN (Potassium voltage-gated channel subfamily A member 2 OS=Homo sapiens OX=9606 GN=KCNA2 PE=1 SV=2) HSP 1 Score: 383.645 bits (984), Expect = 6.433e-127 Identity = 191/393 (48.60%), Postives = 264/393 (67.18%), Query Frame = 1
Query: 391 YDLKEKVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTLEVIE-LPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFF---NKSHCVSGA--------------APNFLDVFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVLVT--FDCDGAKKSASLAFLRVIRLIRVF---KLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHKT 1500
++ E+VVINISGL FET L + P TLLGDP KR Y+D R EYFFDR RP+F++I YYQ+GG+++RPVNVP +IF E+ FY++ + ++ +++DEG+ E LP N+ +R +W+LFE+PE+S A +A++SV ++SIV FC+ET P F N+ SG + +F D FFI+ET+C WF+ E RF +CPSK F +I NIID+ A+IPY++TL L D +++ SLA LRVIRL+RVF KL++HS GLQ+L T +AS+ LGL + L + +ILFSS +Y+AE +SQ SIPDAFWWA+++M TVGYGD VP I GK+VGS+CA++GVLT+A+PVP+I NFN FY +T
Sbjct: 29 HECCERVVINISGLRFETQLKTLAQFPETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFYELGEEAMEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPARIIAIVSVMVILISIVSFCLETLPIFRDENEDMHGSGVTFHTYSNSTIGYQQSTSFTDPFFIVETLCIIWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEKPEDAQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADERESQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRET 421
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. TrEMBL
Match: A0A2H1CQP4 (K+ channel tetramerization domain protein OS=Fasciola hepatica OX=6192 GN=D915_002281 PE=3 SV=1) HSP 1 Score: 566.614 bits (1459), Expect = 0.000e+0 Identity = 266/397 (67.00%), Postives = 323/397 (81.36%), Query Frame = 1
Query: 322 DSGSEKKRRNALEYSSLRSGPFQYDLKEKVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTLEVIELPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFFNKSHCVSGAAPNFLDVFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVLVTFDCDGAKKSASLAFLRVIRLIRVFKLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHKTGRLR 1512
+SGS N E SS + ++V++N+SGL FETW +LN HPTTLLGD KR +YD++R+EYFFDR+RP+FE+IFNYYQ GG+IKRP V D+IFL EL+F+QIEK +++YKK+EG+ EVI LP N+IKR +W+LFE+PETS AFC +V SV FTV+SI+LFCVET P + ++HC GA PNF D FFI+ET+CT WFT E+ RF+SCPS KFIKD+KN+ID+AA++PYY+TLTNVL+TF C+GAK SASLAFLRVIRLIRVFKLTKHS GLQVL+LTF+ SIEGL LFLVA V I++FSS +YY E+ SQIESIPDAFWWA+ITMCTVGYGDKVP+ LGK+VGSVCAV+GVLTLAIPVPIITENFNKFY+HKTGR R
Sbjct: 396 ESGSPVILANEFEPSSSNNSETVCQDCQRVILNVSGLKFETWLAVLNNHPTTLLGDADKRMPFYDEQRKEYFFDRHRPSFEAIFNYYQYGGRIKRPAVVADDIFLRELEFFQIEKDALESYKKNEGYVPEVIILPENRIKRKLWLLFEYPETSPLAFCFSVTSVIFTVISIILFCVETLPVYAQTHCEPGAKPNFRDPFFIIETICTIWFTFELIIRFVSCPSHKKFIKDLKNLIDLAAIVPYYITLTNVLITFSCEGAKSSASLAFLRVIRLIRVFKLTKHSSGLQVLVLTFKESIEGLSLFLVAFIVCILVFSSVLYYVEIDRKGSQIESIPDAFWWAVITMCTVGYGDKVPKGPLGKIVGSVCAVAGVLTLAIPVPIITENFNKFYAHKTGRGR 792
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. TrEMBL
Match: A0A074ZNJ5 (BTB domain-containing protein OS=Opisthorchis viverrini OX=6198 GN=T265_07533 PE=3 SV=1) HSP 1 Score: 566.229 bits (1458), Expect = 0.000e+0 Identity = 274/426 (64.32%), Postives = 336/426 (78.87%), Query Frame = 1
Query: 265 KSNSFKIIWNS-----FKRSLSSNDSGSEKKRRNAL---EYSSLRSGPFQY--DLKEKVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTLEVIELPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFFNKSHCVSGAAPNFLDVFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVLVTFDCDGAKKSASLAFLRVIRLIRVFKLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHKTGRLR 1512
K N +W+S F+R + DS + + N+L EY SG Q + +V++N+SGL FETW+ +L PTT+LGDP KR ++D KR+EYFFDR+RP+FE+IFNYYQ GG +KRP V D+IFL EL+F+QIE + I++YKK EG+ EVI LP KR++W+LFE+PETS+SAFCV+V SV FTV+SI+LFCVET P ++ +HC G PNFLD FFI+ET+CT WFT E+S RF+SCPS+ F+KDIKN+ID+AA++PYY+TLTNVL+TF C+GAK SASL FLRVIRLIRVFKLTKHS GLQVL+LTF+ SIEGL LFLVA V I++FSSTIYY E+ DSQIESIPDAFWWA+ITMCTVGYGDKVP+ LGKLVGSVCAV+GVLTLAIPVPIITENFNKFY+HKTGR R
Sbjct: 321 KKNERSHLWHSGGSASFRRMNTHLDSAPDYIKENSLAISEYLESESGCSQSVDAINRRVILNVSGLKFETWSAVLESRPTTVLGDPEKRRPFWDSKRREYFFDRHRPSFEAIFNYYQYGGCLKRPAVVSDDIFLKELEFFQIEDAAIESYKKSEGYVPEVIVLPEISWKRTLWLLFEYPETSLSAFCVSVTSVLFTVISIILFCVETLPAYSTTHCEPGDRPNFLDPFFIIETMCTIWFTAELSIRFLSCPSRRSFLKDIKNLIDLAAIVPYYLTLTNVLITFSCEGAKSSASLGFLRVIRLIRVFKLTKHSSGLQVLVLTFKESIEGLSLFLVAFIVCILVFSSTIYYVEIDRKDSQIESIPDAFWWAVITMCTVGYGDKVPKGPLGKLVGSVCAVAGVLTLAIPVPIITENFNKFYAHKTGRGR 746
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. TrEMBL
Match: H2KQ48 (Potassium voltage-gated channel protein Shaker OS=Clonorchis sinensis OX=79923 GN=CLF_103220 PE=3 SV=1) HSP 1 Score: 565.844 bits (1457), Expect = 0.000e+0 Identity = 273/426 (64.08%), Postives = 337/426 (79.11%), Query Frame = 1
Query: 265 KSNSFKIIWNS-----FKRSLSSNDSGSEKKRRNAL---EYSSLRSGPFQ--YDLKEKVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTLEVIELPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFFNKSHCVSGAAPNFLDVFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVLVTFDCDGAKKSASLAFLRVIRLIRVFKLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHKTGRLR 1512
K N +W+S F++ + DS S+ + N+L EY SG Q + ++VV+N+SGL FETW+ +L PTT+LGDP KR ++D KR+EYFFDR+RP+FE+IFNYYQ GG +KRP V D+IFL EL+F+Q+E I++YKK EG+ EVI LP KR++W+LFE+PETS+SAFCV+V SV FTV+SI+LFCVET P ++ +HC G PNFLD FFI+ET+CT WFT E+S RF+SCPS+ F+KDIKN+ID+AA++PYY+TLTNVL+TF C+GAK SASL FLRVIRLIRVFKLTKHS GLQVL+LTF+ S+EGL LFLVA V I++FSSTIYY E+ DSQIESIPDAFWWA+ITMCTVGYGDKVP+ LGKLVGSVCAV+GVLTLAIPVPIITENFNKFY+HKTGR R
Sbjct: 311 KKNERSHLWHSGGSVSFRKMNAHLDSASDYIKENSLAISEYLESESGYSQSVAAINQRVVLNVSGLKFETWSAVLESRPTTVLGDPEKRRPFWDSKRREYFFDRHRPSFEAIFNYYQYGGCLKRPAVVSDDIFLKELEFFQLEDDAIESYKKSEGYVPEVIVLPEISWKRTLWLLFEYPETSLSAFCVSVTSVLFTVISIILFCVETLPAYSTTHCEPGDRPNFLDPFFIIETMCTIWFTAELSIRFLSCPSRRSFLKDIKNLIDLAAIVPYYLTLTNVLITFSCEGAKSSASLGFLRVIRLIRVFKLTKHSSGLQVLVLTFKESVEGLSLFLVAFIVCILVFSSTIYYVEIDRKDSQIESIPDAFWWAVITMCTVGYGDKVPKGPLGKLVGSVCAVAGVLTLAIPVPIITENFNKFYAHKTGRGR 736
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. TrEMBL
Match: A0A3R7CF38 (Potassium voltage-gated channel subfamily A member 2 OS=Clonorchis sinensis OX=79923 GN=KCNA2 PE=3 SV=1) HSP 1 Score: 564.303 bits (1453), Expect = 0.000e+0 Identity = 273/426 (64.08%), Postives = 337/426 (79.11%), Query Frame = 1
Query: 265 KSNSFKIIWNS-----FKRSLSSNDSGSEKKRRNAL---EYSSLRSGPFQ--YDLKEKVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTLEVIELPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFFNKSHCVSGAAPNFLDVFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVLVTFDCDGAKKSASLAFLRVIRLIRVFKLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHKTGRLR 1512
K N +W+S F++ + DS S+ + N+L EY SG Q + ++VV+N+SGL FETW+ +L PTT+LGDP KR ++D KR+EYFFDR+RP+FE+IFNYYQ GG +KRP V D+IFL EL+F+Q+E I++YKK EG+ EVI LP KR++W+LFE+PETS+SAFCV+V SV FTV+SI+LFCVET P ++ +HC G PNFLD FFI+ET+CT WFT E+S RF+SCPS+ F+KDIKN+ID+AA++PYY+TLTNVL+TF C+GAK SASL FLRVIRLIRVFKLTKHS GLQVL+LTF+ S+EGL LFLVA V I++FSSTIYY E+ DSQIESIPDAFWWA+ITMCTVGYGDKVP+ LGKLVGSVCAV+GVLTLAIPVPIITENFNKFY+HKTGR R
Sbjct: 361 KKNERSHLWHSGGSVSFRKMNAHLDSASDYIKENSLAISEYLESESGYSQSVAAINQRVVLNVSGLKFETWSAVLESRPTTVLGDPEKRRPFWDSKRREYFFDRHRPSFEAIFNYYQYGGCLKRPAVVSDDIFLKELEFFQLEDDAIESYKKSEGYVPEVIVLPEISWKRTLWLLFEYPETSLSAFCVSVTSVLFTVISIILFCVETLPAYSTTHCEPGDRPNFLDPFFIIETMCTIWFTAELSIRFLSCPSRRSFLKDIKNLIDLAAIVPYYLTLTNVLITFSCEGAKSSASLGFLRVIRLIRVFKLTKHSSGLQVLVLTFKESVEGLSLFLVAFIVCILVFSSTIYYVEIDRKDSQIESIPDAFWWAVITMCTVGYGDKVPKGPLGKLVGSVCAVAGVLTLAIPVPIITENFNKFYAHKTGRGR 786
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. TrEMBL
Match: A0A504Y710 (Potassium voltage-gated channel subfamily A member 3 OS=Fasciola gigantica OX=46835 GN=FGIG_01360 PE=3 SV=1) HSP 1 Score: 561.992 bits (1447), Expect = 0.000e+0 Identity = 258/370 (69.73%), Postives = 311/370 (84.05%), Query Frame = 1
Query: 403 EKVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTLEVIELPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFFNKSHCVSGAAPNFLDVFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVLVTFDCDGAKKSASLAFLRVIRLIRVFKLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHKTGRLR 1512
++V++N+SGL FETW +LN HPTTLLGD KR +YD +R+EYFFDR+RP+FE+IFNYYQ GG+IKRP V D+IFL EL+F+QIEK +++YKK+EG+ EVI LP N IKR +W+LFE+PETS AFC +V SV FTV+SI+LFCVET P + ++HC GA PNF D FFI+ET+CT WFT E+ RF+SCPS FIKD+KN+ID+AA++PYY+TLTNVL+TF C+GAK SASLAFLRVIRLIRVFKLTKHS GLQVL+LTF+ SIEGL LFLVA V I++FSS +YY E+ SQIESIPDAFWWA+ITMCTVGYGDKVP+ LGK+VGSVCAV+GVLTLAIPVPIITENFNKFY+HKTGR R
Sbjct: 423 QRVILNVSGLKFETWLAVLNNHPTTLLGDADKRMPFYDAQRREYFFDRHRPSFEAIFNYYQYGGRIKRPAVVADDIFLRELEFFQIEKDALESYKKNEGYVPEVIILPENHIKRKLWLLFEYPETSPLAFCFSVTSVIFTVISIILFCVETLPVYAQTHCEPGAKPNFRDPFFIIETICTIWFTFELIIRFVSCPSHKTFIKDLKNLIDLAAIVPYYITLTNVLITFSCEGAKSSASLAFLRVIRLIRVFKLTKHSSGLQVLVLTFKESIEGLSLFLVAFIVCILVFSSVLYYVEIDRKGSQIESIPDAFWWAVITMCTVGYGDKVPKGPLGKIVGSVCAVAGVLTLAIPVPIITENFNKFYAHKTGRGR 792
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Cavefish
Match: kcna2a (potassium voltage-gated channel subfamily A member 2 [Source:NCBI gene;Acc:103030675]) HSP 1 Score: 384.03 bits (985), Expect = 4.814e-128 Identity = 194/393 (49.36%), Postives = 264/393 (67.18%), Query Frame = 1
Query: 379 GPFQYDLKEKVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTLEVIE-LPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFF----NKSHCVSGAAPN---------FLDVFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVLVTFDCDG--AKKSASLAFLRVIRLIRVF---KLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHKT 1500
G + + E+VVINISGL FET L++ P TLLGDP KR Y+D R EYFFDR RP+F++I YYQ+GG+++RPVNV +IF E+ FY++ + I+ +++DEG E LP N+ ++ +W+LFE+PE+S A +A++SV ++SIV FC+ET P F + H V N F D FFILET+C WF+ E RF +CPSK F +I N+IDV A+IPY++TL L DG +++ SLA LRVIRL+RVF KL++HS GLQ+L T +AS+ LGL + L + +ILFSS +Y+AE P+SQ SIPDAFWWA+++M TVGYGD VP I GK+VGS+CA++GVLT+A+PVP+I NFN FY +T
Sbjct: 24 GEAEQECCERVVINISGLRFETQLKTLSQFPETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVTLDIFSEEIRFYELGEEAIEMFREDEGFIKEEERPLPDNEFQKQVWLLFEYPESSGPARIIAIISVMVILISIVSFCLETLPIFRSDEEEMHKVRTYNSNSTTSYTSTYFTDPFFILETLCIIWFSFEFLVRFFACPSKASFFVNIMNMIDVVAIIPYFITLGTELAEKAEDGQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADEPESQFYSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRET 416
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Cavefish
Match: KCNA3 (potassium voltage-gated channel subfamily A member 3 [Source:NCBI gene;Acc:103031324]) HSP 1 Score: 384.415 bits (986), Expect = 1.041e-127 Identity = 190/388 (48.97%), Postives = 262/388 (67.53%), Query Frame = 1
Query: 403 EKVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTLEVIE-LPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFFNKSH--------------CVSGAAP----NFLDVFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVLVTFDCDGAKKSASLAFLRVIRLIRVF---KLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHKT 1500
E+VVINISGL FET ++ P TLLGDP KR Y+D R EYFFDR RP+F++I YYQ+GG+I+RPVNVP ++F E+ FYQ+ + ++ +++DEG E LP+ + +R +W+LFE+PE+S A +A++SV ++SIV+FC+ET P F +G AP F D FF++ET+C WF+ E+ RF +CPSK F K+I NIID+ A+IPY++TL L +G +++ SLA LRVIRL+RVF KL++HS GLQ+L T +AS+ LGL + L + +ILFSS +Y+AE +P S SIPDAFWWA++TM TVGYGD P I GK+VGS+CA++GVLT+A+PVP+I NFN FY +T
Sbjct: 68 ERVVINISGLRFETQLKTFSQFPDTLLGDPRKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRIRRPVNVPIDVFSEEIRFYQLGEEAMEKFREDEGFIKEEERPLPSREFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPEFRDDREAAAAAAAAAAAVPLNNGTAPYGPGAFTDPFFVIETLCIVWFSFELLVRFFACPSKATFSKNIMNIIDIVAIIPYFITLGTELAERQGNG-QQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADDPASSFSSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRET 454
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Cavefish
Match: kcna2b (potassium voltage-gated channel subfamily A member 2 [Source:NCBI gene;Acc:103039676]) HSP 1 Score: 382.489 bits (981), Expect = 1.838e-127 Identity = 193/389 (49.61%), Postives = 262/389 (67.35%), Query Frame = 1
Query: 391 YDLKEKVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTLEVIE-LPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFF-NKSHCVSGAAPN------------FLDVFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVLVTFDCDG--AKKSASLAFLRVIRLIRVF---KLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHKT 1500
++ E+VVINISGL FET L++ P TLLGDP KR Y+D R EYFFDR RP+F++I YYQ+GG+++RPVNV +IF E+ FY++ + I+ +++DEG E + LP N+ +R +W+LFE+PE+S A +A++SV ++SIV FC+ET P F N + P F D FFILET+C WF+ E RF +CPSK F +I NIID+ A+IPY++TL L DG +++ SLA LRVIRL+RVF KL++HS GLQ+L T +AS+ LGL + L + +ILFSS +Y+AE DSQ SIPDAFWWA+++M TVGYGD VP I GK+VGS+CA++GVLT+A+PVP+I NFN FY +T
Sbjct: 28 HECCERVVINISGLRFETQLKTLSQFPDTLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVTLDIFSEEIRFYELGEEAIEIFREDEGFIKEEEKPLPENEFQRQVWLLFEYPESSGPARIIAIISVMVILISIVSFCLETLPIFRNDDIDMRKTYPGNSNSTTSYTSTYFTDPFFILETLCIIWFSFEFLVRFFACPSKAGFFVNIMNIIDIVAIIPYFITLGTELAESPEDGQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADEADSQFVSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRET 416
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Cavefish
Match: ENSAMXT00000027012.2 (potassium voltage-gated channel subfamily A member 2-like [Source:NCBI gene;Acc:103027793]) HSP 1 Score: 377.096 bits (967), Expect = 7.575e-125 Identity = 198/437 (45.31%), Postives = 280/437 (64.07%), Query Frame = 1
Query: 307 SLSSNDSGSEKKRRNALEYSSLRSGPFQYDLKEKVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTLEVIE-LPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFF------------------------NKSHC---VSGAAPNFL------DVFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVLV--TFDCDGAKKSASLAFLRVIRLIRVF---KLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHKT 1500
++ S D E+ NA++ R P +++ E+VVINISGL FET L + P TLLGDP KR+ Y+D R EYFFDR RP+F++I YYQ+GG+++RPVNVP ++F E+ FY++ + ++ +++DEG E LP + +R +W+LFE+PE+S A +A++SV ++SIV+FC+ET P F N+ H ++G P L D FF++ET+C WF+ E+ RF +CPSK F K+I NIID+ A+IPY++TL L G +++ SLA LRVIRL+RVF KL++HS GLQ+L T +AS+ LGL + L + +ILFSS +Y+AE +PDS SIPDAFWWA++TM TVGYGD P I GK+VGS+CA++GVLT+A+PVP+I NFN FY +T
Sbjct: 49 TVVSCDGAPEEPNSNAVD----RYEP-EHECCERVVINISGLRFETQLKTLAQFPETLLGDPRKRTAYFDPLRNEYFFDRNRPSFDAILYYYQSGGRVRRPVNVPIDVFTEEIRFYELGEEAMEKFREDEGFIKEEERALPAGEFQRQVWLLFEYPESSGPARGIAIVSVLVILVSIVIFCLETLPEFRDDDSDVTRDRVGTTPLHMLNHYPNEMHGHGNLTGGLPPILSGTPFSDPFFVVETLCIVWFSFELLVRFFACPSKATFSKNIMNIIDIVAIIPYFITLGTELAERQQGNGGGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADDPDSGFNSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRET 480
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Cavefish
Match: kcna1a (potassium voltage-gated channel subfamily A member 1 [Source:NCBI gene;Acc:103039047]) HSP 1 Score: 369.007 bits (946), Expect = 2.659e-122 Identity = 187/388 (48.20%), Postives = 263/388 (67.78%), Query Frame = 1
Query: 388 QYDLKEKVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTLEVIE-LPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFFNKS-----HCVSGAA----PNFL-DVFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVLVT--FDCDG-AKKSASLAFLRVIRLIRVF---KLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHKT 1500
+D E+VVINI+GL FET L + P TLLG+P KR Y+D R EYFFDR RP+F++I YYQ+GG+++RP +VP ++F E+ FY++ ++ +++DEG E LP + +R IW+LFE PE+S A +A++SV ++SIV+FC+ET P ++ + + P+ L D FFI+ET+C WF+ E+ RF++CPSK F KD+ N IDV A+IPY++TL L + DG +++ SLA LRVIRL+RVF KL++HS GLQ+L LT +AS+ LGL + L + +ILFSS +Y+AE DS SIPDAFWWA+++M TVGYGD VP I GK+VGS+CA++GVLT+A+PVP+I NFN FY +T
Sbjct: 29 DHDCCERVVINIAGLRFETELKTLAQFPETLLGNPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPASVPLDMFSEEIKFYELGYEAMEKFREDEGFIREKERPLPEAEFQRQIWLLFEHPESSGPARGIAIVSVTVILVSIVIFCLETLPQLKENPEGHIQIIGNSTFYYKPSLLTDPFFIVETLCIIWFSFELIVRFLACPSKAAFFKDMMNTIDVVAIIPYFITLGTELAEDPNNKDGKGEQATSLAILRVIRLVRVFRIFKLSRHSKGLQILGLTLKASMRELGLLVFFLFIGVILFSSAVYFAEAEEADSYFGSIPDAFWWAVVSMTTVGYGDMVPVTIGGKVVGSLCAIAGVLTIALPVPVIVSNFNYFYHRET 416
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Sea Lamprey
Match: KCNA3 (potassium voltage-gated channel subfamily A member 3 [Source:HGNC Symbol;Acc:HGNC:6221]) HSP 1 Score: 365.925 bits (938), Expect = 1.414e-121 Identity = 184/389 (47.30%), Postives = 268/389 (68.89%), Query Frame = 1
Query: 382 PFQYDLKEKVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTLEVIE-LPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFFNK-------SHCVSGAA----PNFLDVFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTL-TNVLVTFDCDGAKKSASLAFLRVIRLIRVF---KLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHKT 1500
P +D E+VVIN+SGL FET L + P TLLGDP KR Y+D R EYFFDR RP+F++I YYQ+GG+++RPV+VP +IF E+ FY + + + Y++DEG+ E + LP N+ +R +W+LFE+PE+S A +A++SV ++SI++FC+ET P F S+ +G F D FFI+ET+C WF+ E+ RF +CPSKV+F K++ NIID+ A++PY++TL T + +++ SLA LRVIRL+RVF KL++HS GLQ+L T AS+ LGL + L + +ILFSS +++AEV + ++ +SIPDAFWW+++TM TVGYGD P+ + GK+VGS+CA++GVLT+++PVP+I NFN FY +T
Sbjct: 31 PGGHDFCERVVINVSGLRFETQLRTLAQFPDTLLGDPQKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVSVPYDIFTEEVRFYDLGEETMLRYREDEGYVKEPEKPLPENEFQRQVWLLFEYPESSSPARAIAIVSVLVILISIIIFCLETLPEFRDDADLYKVSYYTNGTHYFYHNVFADPFFIMETICIIWFSFELMVRFCACPSKVEFGKNLMNIIDIVAIVPYFITLGTEMAEQTGSANGQQTMSLAILRVIRLVRVFRIFKLSRHSKGLQILGHTLHASMRELGLLIFFLFIGVILFSSAVFFAEVDSKKTEFQSIPDAFWWSLVTMTTVGYGDMSPKTVGGKIVGSLCAIAGVLTVSLPVPVIVSNFNYFYQRET 419
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Sea Lamprey
Match: KCNA3 (potassium voltage-gated channel subfamily A member 3 [Source:HGNC Symbol;Acc:HGNC:6221]) HSP 1 Score: 365.155 bits (936), Expect = 1.703e-121 Identity = 184/400 (46.00%), Postives = 268/400 (67.00%), Query Frame = 1
Query: 355 LEYSSLRSGPFQYDLKEKVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTLEVIE-LPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFF--------------NKSHCVSGAAPNFLDVFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVLVTFDCDGAKKSASLAFLRVIRLIRVF---KLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHKT 1500
LE + P ++ E++VIN+SGL FET L++ P TLLG+PSKRS Y+D R EYFFDR RP+F++I YYQ+GG+++RPVNV ++F E+ FY++ + +++DEG E + LP+++ +R +W+LFE+PE+S A +A++SV ++SI++FC+ET P F N + +F D FFI+ET+C WF+ E+ RF +CPSK F K I NIID+ A++PY++TL + G +++ SLA LRVIRL+RVF KL++HS GLQ+L T +AS+ LGL + L + +ILFSS +Y+AE + +S+ SIPDAFWWA++TM TVGYGD P + GK+VGS+CA++GVLT+A+PVP+I NFN FY +T
Sbjct: 12 LEDGPETAEPLTHEYCERIVINVSGLRFETQLKSLDQFPDTLLGNPSKRSRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVSIDVFSEEIKFYELGNEAMAKFQEDEGFIKEEEKPLPSDEFQRQVWLLFEYPESSNPARGIAIVSVLVILISIIIFCLETLPEFRDEKEQKFLPAKDINGTQVKIMHGSSFTDPFFIVETICIIWFSFELLVRFFACPSKPGFFKSIMNIIDIVAILPYFITLGTEMAKHQGSG-QQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADHQNSEFRSIPDAFWWAVVTMTTVGYGDMRPVTVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRET 410
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Sea Lamprey
Match: KCNA3 (potassium voltage-gated channel subfamily A member 3 [Source:HGNC Symbol;Acc:HGNC:6221]) HSP 1 Score: 326.25 bits (835), Expect = 2.465e-107 Identity = 173/379 (45.65%), Postives = 242/379 (63.85%), Query Frame = 1
Query: 457 LNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTLEVIE-LPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFFNKSHCVSGAAPN-------------------------FLDVFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVLVTFD--CDGAKKSASLAFLRVIRLIRVF---KLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHKT 1500
L P TLLGDP KR Y+D R EYFFDR RP+F++I YYQ+ GK++RP NVP +IF E+ FY++ + + Y++DEG+ E + LP N ++R +W+LFE+PE+S A +A++SV V+SIV+F ET P F + + D FFI+ETVC WF+ E+ RF +CPSK F K+I N ID+ A++PY++TL L D + +++ SLA LRVIRL+RVF KL++HS GLQ+L T RAS+ LGL + L + +ILFSS IY+AEV +P++ SIP+AFWW+++TM TVGYGD P + GK+VGS+CA++GVLT+A+PVP+I NFN FY +
Sbjct: 5 LAHFPDTLLGDPQKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSRGKLRRPTNVPYDIFAEEVRFYELGEETMARYREDEGYVKEEEKPLPENALQRQVWLLFEYPESSNPARVIAIVSVLVIVISIVIFVAETLPEFRDDKDLHSGTRHDVGAGDAAVAAAGNSSGGSSGGGSGHADPFFIVETVCIVWFSFELLVRFCACPSKPGFFKNIMNTIDIVAIMPYFITLGTELAAQDTGANNGQQTMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLRASMRELGLLIFFLFIGVILFSSAIYFAEVDDPNTHFHSIPEAFWWSLVTMTTVGYGDMFPVTLGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRGS 383
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Sea Lamprey
Match: kcna1b (potassium voltage-gated channel, shaker-related subfamily, member 1b [Source:ZFIN;Acc:ZDB-GENE-140515-1]) HSP 1 Score: 321.242 bits (822), Expect = 7.795e-106 Identity = 152/378 (40.21%), Postives = 237/378 (62.70%), Query Frame = 1
Query: 403 EKVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTLEVIELPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFFNKSHCVSGAAPNF--------LDVFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVLVTFDCDGAKKSASLAFLRVIRLIRVFKLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHKTGRLR 1512
++VVIN+SG FET L++ P +LLG P KR+ Y+D + EYFFDR F++I YYQ+GG++ +PV+VP ++F E++FY++ + + Y ++ T E + ++ +W LFE + S++A ++++S T+LSI + C+ET P F K + V F LD FF+LET C WF E++ RF +CPSK F+KD N ID+ A++PY++T+ VL + L +R++R++R+FKL++H LQ+L LT +AS+ L + L V++++FS IYY E +P SIPDAFWWA++TM VGYGD P + GK+VG++CA++GVLT+++PVP+I NF FY+ K ++
Sbjct: 1 QRVVINVSGERFETQLKTLDQFPDSLLGHPDKRARYFDPLQNEYFFDRSHVNFDAILFYYQSGGRLCKPVDVPSDVFREEVEFYELGEEAVAKYGENTLDTPEEENVHGKDFQQHVWRLFESRDGSIAAKMLSLMSFVTTILSITVMCLETLPQFRKDNQVHANRTEFSIRTSIYNLDPFFMLETACVVWFIFELAVRFYACPSKTSFMKDFMNAIDILAIMPYFITV--VLEIMQQQDQTRQPLLKIIRLVRVLRIFKLSRHCQDLQILGLTLKASLRELAMLSFFLFVAVVIFSGAIYYVEADDPQKHFSSIPDAFWWAVVTMTLVGYGDMWPMTVGGKIVGALCAITGVLTISLPVPVIVSNFKYFYNLKNKDIK 376
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Sea Lamprey
Match: kcna1b (potassium voltage-gated channel, shaker-related subfamily, member 1b [Source:ZFIN;Acc:ZDB-GENE-140515-1]) HSP 1 Score: 320.857 bits (821), Expect = 9.469e-106 Identity = 152/378 (40.21%), Postives = 237/378 (62.70%), Query Frame = 1
Query: 403 EKVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTLEVIELPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFFNKSHCVSGAAPNF--------LDVFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVLVTFDCDGAKKSASLAFLRVIRLIRVFKLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHKTGRLR 1512
++VVIN+SG FET L++ P +LLG P KR+ Y+D + EYFFDR F++I YYQ+GG++ +PV+VP ++F E++FY++ + + Y ++ T E + ++ +W LFE + S++A ++++S T+LSI + C+ET P F K + V F LD FF+LET C WF E++ RF +CPSK F+KD N ID+ A++PY++T+ VL + L +R++R++R+FKL++H LQ+L LT +AS+ L + L V++++FS IYY E +P SIPDAFWWA++TM VGYGD P + GK+VG++CA++GVLT+++PVP+I NF FY+ K ++
Sbjct: 5 QRVVINVSGERFETQLKTLDQFPDSLLGHPDKRARYFDPLQNEYFFDRSHVNFDAILFYYQSGGRLCKPVDVPSDVFREEVEFYELGEEAVAKYGENTLDTPEEENVHGKDFQQHVWRLFESRDGSIAAKMLSLMSFVTTILSITVMCLETLPQFRKDNQVHANRTEFSIRTSIYNLDPFFMLETACVVWFIFELAVRFYACPSKTSFMKDFMNAIDILAIMPYFITV--VLEIMQQQDQTRQPLLKIIRLVRVLRIFKLSRHCQDLQILGLTLKASLRELAMLSFFLFVAVVIFSGAIYYVEADDPQKHFSSIPDAFWWAVVTMTLVGYGDMWPMTVGGKIVGALCAITGVLTISLPVPVIVSNFKYFYNLKNKDIK 380
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Nematostella
Match: SHAK4 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SHB6]) HSP 1 Score: 339.347 bits (869), Expect = 5.833e-112 Identity = 188/383 (49.09%), Postives = 249/383 (65.01%), Query Frame = 1
Query: 403 EKVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTLEVIE-LPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFFNKSH-----CVSGA-AP---NFLDVFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVLVTFDCDGAKKSASLAFLRVIRLIRVF---KLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHKTGRLR 1512
++++IN+SGL FET L +P TLLG+ KR+ YYD R EYFFDR RPAF++I YYQ+GGK+ RP NVP ++F E+ FY++ V+ +++EG+ E LP NK++R IW LFEFP+TS+ A VA+ SV LSIV FC+ET P F K V+G P F +F +ET C WFT E R IS P K+ FI+ N+ID+ A++PYY+TL K++SL LRVIRL+RVF KL++HS GLQ+L T RAS+ LGL + L + +ILFSS +YYAE G + +SIPDAFWWA++TM TVGYGD P + GK+VGS+CA+SGVLT+A+PVP+I NFN FY H+ R
Sbjct: 58 DRILINVSGLKFETHVQTLESNPDTLLGNAVKRAKYYDSVRNEYFFDRNRPAFDAILFYYQSGGKLLRPANVPMDVFADEIRFYELGDDVLHKVEQEEGYIEEEKPILPENKLQRQIWQLFEFPDTSMPARFVAIFSVFVITLSIVTFCIETLPQFQKKEEDLYVSVNGTLVPVDNRFDQPWFSMETACIIWFTFEYIMRLISSPQKLIFIRSFLNMIDIVAILPYYITLPM--------QDTKASSLGVLRVIRLVRVFRIFKLSRHSRGLQILGHTLRASLRELGLLIFFLLIGVILFSSAVYYAEGGEKGTHFKSIPDAFWWAVVTMTTVGYGDMRPITVWGKIVGSLCAISGVLTIALPVPVIVSNFNYFY-HRENEQR 431
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Nematostella
Match: SHAKR1 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S3Y6]) HSP 1 Score: 311.612 bits (797), Expect = 3.784e-102 Identity = 167/375 (44.53%), Postives = 242/375 (64.53%), Query Frame = 1
Query: 403 EKVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSV----IDAYKKDEGHTLEVIELPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFFNKSHCVSGAAPNFLDVFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVLVTFDCDGAKKSASLAFLRVIRLIRVF---KLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHKTGR 1506
++V IN+SG+ +ET L+ PT+LLG KRS+Y+D ++EYFFDR R AF+SI +YQ+ GK+ RPV++ + F+ E+ F+++E V I+AY D T V ++P N I+R IW + E P +S +A VAV SV +LSIV+FC+ET P ++ +A + +E +C WFT+E+ RF++CP+K FI NIIDV A++PYY+ L K +++LAFLR++RL+RVF KL++H GL+VL LT +AS+ L L L + +I+FSS +YYAE + SIP+AFW++++TM TVGYGDK P GKLVGS+CA++GVLTLA+PVP+I NF+ FY+ R
Sbjct: 1 KRVKINVSGMVYETLESTLDRFPTSLLGCREKRSVYFDSMKKEYFFDRNRVAFDSILYFYQSNGKLLRPVDLDMKTFVNEVYFFELEDLVSHQFIEAYGSD---TSLVSKMPDNAIQRKIWEVLELPHSSFTAQVVAVWSVGVILLSIVVFCIETLPGLRETRTEKSSA------LYSIEILCVAWFTLELLLRFLTCPNKPHFIISFLNIIDVLAILPYYIML-------GLGDTKDTSTLAFLRILRLVRVFRIFKLSRHYRGLKVLGLTLKASLRELLLLTFFLLMGVIVFSSGVYYAE----STHFSSIPEAFWFSVVTMTTVGYGDKAPLSTWGKLVGSMCAIAGVLTLALPVPVIVSNFSFFYNQDRDR 355
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Nematostella
Match: SHAK6 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SFM4]) HSP 1 Score: 311.227 bits (796), Expect = 6.822e-102 Identity = 168/380 (44.21%), Postives = 236/380 (62.11%), Query Frame = 1
Query: 403 EKVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQI-EKSVIDAYKKDEGHTLEVIELPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFF----------NKSHCVSGAAPNFLDVFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVLVTFDCDGAKKSASLAFLRVIRLIRVF---KLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVG-NPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHK 1497
+++ INISGL +ET+ L P +LLG S+R +YD EYFFDR R FESI YYQ G + RP N+P ++F++++ ++ + E+++ A E E+ +P NK +R++W LFE P+TS A +A+ SVA VLSIVLFCVET P F N + + P VFF +E+ C WFT+E RF+ P K KF+ + N+ID+ A++P+++TL T +SLA LR +RL+RVF KL+++S GLQ+L T +AS+ LGL L V +ILFSS +YYAE N D++ SIP +FWW+IITM TVGYGD P+ + GKLVG CA+SGVL +A+PVP+I NF +YS +
Sbjct: 1 KRITINISGLRYETFDKTLERFPESLLGCKSRRDDFYDSVNDEYFFDRNRLCFESILAYYQTCGVLIRPPNIPRKVFVSDIKYFDLGEQALRQAGDDLEITDREIRPMPKNKFQRTVWSLFEHPDTSNGARAIAIFSVAVIVLSIVLFCVETLPQFQRRPKEVLRNNITETIMIDNPK-KSVFFAIESFCIAWFTLEYFIRFLCSPDKCKFVVSVLNLIDLVAILPFFITLPMTEPT-------SVSSLAILRCVRLVRVFRIFKLSRYSRGLQILGHTLKASLRELGLLFFFLCVGVILFSSAVYYAEYNYNRDTEFLSIPHSFWWSIITMTTVGYGDMAPKTLGGKLVGCFCAISGVLAIALPVPVIVSNFAYYYSRE 372
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Nematostella
Match: SHAK3 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SK45]) HSP 1 Score: 310.842 bits (795), Expect = 1.925e-101 Identity = 170/386 (44.04%), Postives = 237/386 (61.40%), Query Frame = 1
Query: 403 EKVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTLEVIE-LPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFFN-KSHCVSGAAPNFL----------------DVFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVLVTFDCDGAKKSASLAFLRVIRLIRVF---KLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHK 1497
++++IN+SGL FET+ L + P TLLG SKR Y+D EYFFDR R FE+I +YQ+ GK+ RP VP +F E+ F+++ K + +++EG+ E LP + ++R IW LFE+P++S+ A +AV SV+ ++SIV+FC+ET P F K+ P L + LE +C WFT+E R +S P K+ F++ N+ID+ A++PYY+TL + SLA LRVIRL+RVF KL++HS GLQVL T RAS L + + L +S++LFSS +YYAE S+ SIPDAFWWA++TM TVGYGD P GKLVGS+CA+SGVLT+A+PVP+I NFN FY +
Sbjct: 1 KRIIINVSGLRFETYEATLAQFPNTLLGSESKREEYFDSDADEYFFDRNRSTFEAILFFYQSNGKLVRPSGVPFLLFKDEVIFFKLGKDNLKRLEEEEGYIEETTRVLPRHHLQRRIWELFEYPDSSMGARVLAVWSVSVILISIVVFCIETLPTFRCKTSPDGNGCPKLLPGTNSTADHPEPVEKSSAWLALEILCIAWFTLEYVVRLLSSPQKLLFVRSFLNVIDLMAILPYYITLPM--------KDLRITSLAVLRVIRLVRVFRIFKLSRHSRGLQVLGHTLRASSRELAMLIFFLLISVVLFSSAVYYAEEEEAASKFSSIPDAFWWAVVTMTTVGYGDMYPVTPWGKLVGSICAISGVLTIALPVPVIVSNFNYFYKRE 378
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Nematostella
Match: SHAK5 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SAS8]) HSP 1 Score: 300.827 bits (769), Expect = 9.540e-98 Identity = 160/385 (41.56%), Postives = 234/385 (60.78%), Query Frame = 1
Query: 406 KVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKK---DEGHTLEVIELPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFF-----------------NKSHCVSGAAPNFLDVFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVLVTFDCDGAKKSASLAFLRVIRLIRV---FKLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQI-ESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFY 1488
+V +N+SG ++T+ L++ PTTLLGDP+KR Y+D EYFFDR + FE I +YQ+ G++ P ++ EI L E++F+ + ++ I+A K+ DE ++PTNKI+ W LFE+ ++S +A +A+ SV+ V SI + CVET P F NK + + A + F LE WFT+E RF+S P K F++ N+ID+ A++P+Y+ L+ + SLAFLR++RL+RV FKL++HS GLQ+L LT R S+ LGL + L + +++FSS YYAE G D+ + SIPD FWWA++TM TVGYGD VP+ + GKLVGS CA+ GVL +A+PVP+I NF+ Y
Sbjct: 1 RVTLNVSGFRYQTYVETLDKFPTTLLGDPAKRREYFDPDLNEYFFDRNKQVFEIILYFYQSNGRLVCPPDLAPEILLEEVEFFDLGETAINAVKELLTDEEPDETPRDMPTNKIQTQFWNLFEYADSSKAARVIALFSVSIIVASIAVLCVETLPNFAILPIHDPNNTEEVRRVNKHNEGAILARRW---FGYLEAAFIAWFTLEYLVRFLSSPKKCPFVRSFLNVIDILAIVPFYID----LILNSVQSNDGTLSLAFLRILRLVRVFRIFKLSRHSSGLQILGLTLRKSLRELGLLIFFLFIGVVIFSSMAYYAEAGTKDTHLGRSIPDTFWWALVTMTTVGYGDLVPKTLWGKLVGSCCALCGVLAIALPVPVIVSNFDAIY 378
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Medaka
Match: ENSORLT00000004658.2 (pep primary_assembly:ASM223467v1:6:13425755:13435070:-1 gene:ENSORLG00000003738.2 transcript:ENSORLT00000004658.2 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 395.971 bits (1016), Expect = 2.231e-133 Identity = 196/387 (50.65%), Postives = 270/387 (69.77%), Query Frame = 1
Query: 382 PFQYDLKEKVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTLEVIE-LPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFF---------NKSHCVSGAAPN-FLDVFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVLVTFDCDGAKKSASLAFLRVIRLIRVF---KLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHKT 1500
P + E++VINISGL FET L+ PTTLLGDP KR +YD R EYFFDR RP+F++I YYQ+GG+++RPV+VP +IFL EL FY++E+ VI+ +K DEG E LP+N+ +R +W+LFE+PE+S A +A++SV ++SIV+FC+ET P F + + G P+ F D FF++ET+C WF+ E RF+SCPSK F K+I N+IDV A+ PY++TL L ++++ASLA LRVIRL+RVF KL++HS GLQ+L T RAS+ LGL + L + ++LFSS++Y+AEV +P+S+ SIPDAFWWA++TM TVGYGD P I GK VGS+CA++GVLT+A+PVP+I NFN FY +
Sbjct: 26 PADQECSERLVINISGLRFETQLKTLSRFPTTLLGDPRKRIRFYDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVSVPVDIFLEELKFYELEEEVIELFKDDEGLPREEERPLPSNEFQRQVWLLFEYPESSGPARMIAIVSVMVILISIVIFCLETLPEFKDVPPEPDNHANGSAHGKEPSPFTDPFFMVETLCIVWFSFEFMMRFLSCPSKPVFFKNIMNLIDVVAIAPYFITLGMDLAEHQ-GSSQQAASLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLRASLRELGLLIFFLIIGVVLFSSSVYFAEVEDPNSEFSSIPDAFWWAVVTMTTVGYGDMCPTTIGGKFVGSLCAIAGVLTIALPVPVIVSNFNYFYHREN 411
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Medaka
Match: kcna2a (potassium voltage-gated channel, shaker-related subfamily, member 2a [Source:ZFIN;Acc:ZDB-GENE-131113-1]) HSP 1 Score: 390.963 bits (1003), Expect = 3.708e-131 Identity = 196/390 (50.26%), Postives = 265/390 (67.95%), Query Frame = 1
Query: 403 EKVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTLEVIE-LPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFF-------NKSHC-----------VSGAAPNFLDVFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVLVTFDCDG--AKKSASLAFLRVIRLIRVF---KLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHKT 1500
E+VVINISGL FET L++ P TLLGDP KR Y+D R EYFFDR RP+F++I YYQ+GG+++RPVNV +IF E+ FY++ + I+ +++DEG E LP N+ +R +W+LFE+PE+S A +A++SV ++SIV FC+ET P F +KSH +S + F D FFILET+C WF+ E RF +CPSK F +I NIID+ A+IPY++TL L DG +++ SLA LRVIRL+RVF KL++HS GLQ+L T +AS+ LGL + L + +ILFSS +Y+AE P+SQ ESIPDAFWWA+++M TVGYGD VP I GK+VGS+CA++GVLT+A+PVP+I NFN FY +T
Sbjct: 29 ERVVINISGLRFETQLKTLSQFPETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVTLDIFSEEIRFYELGEEAIEMFREDEGFIKEEERPLPDNEFQRQVWLLFEYPESSGPARIIAIISVMVILISIVSFCLETLPIFRNDEDDMHKSHAKVFSPETNTTIISYTSTYFTDPFFILETLCIIWFSFEFLVRFFACPSKAGFFGNIMNIIDIVAIIPYFITLGTELADRPEDGQPGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADEPESQFESIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRET 418
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Medaka
Match: KCNA3 (potassium voltage-gated channel subfamily A member 3-like [Source:NCBI gene;Acc:105354379]) HSP 1 Score: 388.652 bits (997), Expect = 2.083e-129 Identity = 191/386 (49.48%), Postives = 267/386 (69.17%), Query Frame = 1
Query: 391 YDLKEKVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTLEVIE-LPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFFNKSH--------CVSGAAPNFL----DVFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVLVTFDCDGAKKSASLAFLRVIRLIRVF---KLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHKT 1500
++ E+VVINISGL FET L++ P TLLGDP KR Y+D R EYFFDR RP+F++I YYQ+GG+I+RPVNVP +IF E+ FY++ + ++ +++DEG E LP N+ +R +W+LFE+PE+S A VA++SV ++SIV+FC+ET P F + ++G P F+ D FF++ET+C WF+ E+ RF +CPSK F K+I NIID+ A++PY++TL L +G +++ SLA LRVIRL+RVF KL++HS GLQ+L T +AS+ LGL + L + +ILFSS +Y+AE +P S SIPDAFWWA++TM TVGYGD P I GK+VGS+CA++GVLT+A+PVP+I NFN FY +T
Sbjct: 70 HECCERVVINISGLRFETQLKTLSQFPETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRIRRPVNVPIDIFSEEIRFYELGEEAMEKFREDEGFIKEEERPLPENEFQRQVWLLFEYPESSGPARGVAIVSVLVILISIVIFCLETLPEFRDENNDVITLAPVINGTVPYFISPFSDPFFVVETLCIIWFSFELLVRFFACPSKATFSKNIMNIIDIVAIVPYFITLGTELAERQGNG-QQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADDPSSGFSSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRET 454
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Medaka
Match: ENSORLT00000025729.2 (shaker-related potassium channel tsha2 [Source:NCBI gene;Acc:101167693]) HSP 1 Score: 385.956 bits (990), Expect = 4.112e-129 Identity = 190/386 (49.22%), Postives = 266/386 (68.91%), Query Frame = 1
Query: 394 DLKEKVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTLEVIE-LPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVET-------------HPFFNKSHCVSGAAPNFLDVFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVLVTFDCDGAKKSASLAFLRVIRLIRVF---KLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHKT 1500
D E+VVINISGL FET L + P TLLGDP KR ++D R EYFFDR RP+F++I YYQ+GG+++RPVNVP +IF+ E+ FY++ + VI+ +K+DEG E LP ++ +R +W+LFE+PE+S +A +A++SV ++SIV+FC+ET P+ N + A P F D FFI+ET+C WF+ E+ RF++CPSK F K+I N ID+ A++PY++TL L +G +++ SLA LRVIRL+RVF KL++HS GLQ+L T +AS+ LGL + L + +ILFSS +Y+AE +P S SIPDAFWWA+++M TVGYGD P I GK+VGS+CA++GVLT+A+PVP+I NFN FY +T
Sbjct: 33 DCCERVVINISGLRFETQLKTLAQFPATLLGDPRKRMRFFDPLRNEYFFDRNRPSFDAIVYYYQSGGRLRRPVNVPVDIFMEEIKFYELGEEVIENFKEDEGFIKEEERPLPEHEFQRQVWLLFEYPESSGAARGIAIVSVLVILISIVIFCLETLPEFREDARDLEAQPYVNGTASADRANP-FTDPFFIVETLCIIWFSFELLVRFLACPSKPAFFKNIMNTIDIVAIMPYFITLGLELAEHQGNG-QQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAETDDPHSGFSSIPDAFWWAVVSMTTVGYGDMCPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRET 416
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Medaka
Match: ENSORLT00000008056.2 (pep primary_assembly:ASM223467v1:5:13015115:13021828:-1 gene:ENSORLG00000006413.2 transcript:ENSORLT00000008056.2 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 384.8 bits (987), Expect = 7.395e-128 Identity = 198/422 (46.92%), Postives = 272/422 (64.45%), Query Frame = 1
Query: 307 SLSSNDSGSEKKRRNALEYSSLRSGPFQYDLKEKVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTLEV-IELPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFFNKS--------HCVSGAAPN----------FLDVFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVLVTFDCD--GAKKSASLAFLRVIRLIRVF---KLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHKT 1500
S S DS K ++ + L + D EKVVINISGL FET LN+ P TLLGDP KR Y+D + EYFFDR RP+F+ I YYQ+GG+++RP NVP +IF E+ FY++ ++ +++DEG T E + LPTN++KR W+LFE+PE+S +A A++SV V+SI +FC+ET P F + ++G + D FFI+ET+C WF EV RF+ CPSK +F +I NIID+ ++IPY+VTL L T D + ++ SLA LR+IRL+RVF KL++HS GLQ+L T +AS+ LGL + L + +ILFSS IY+AEV P +Q SIPD FWWA++TM TVGYGD P + GK+VG++CA++GVLT+A+PVP+I NFN FY +T
Sbjct: 52 SESPTDSVFSKMPKDYYDNEDLFEKHYMEDKDEKVVINISGLMFETQLSTLNKFPETLLGDPMKRINYFDPMKNEYFFDRNRPSFDGILYYYQSGGRLRRPANVPLDIFANEIVFYELGHEAMEQFREDEGFTKEPEVLLPTNELKRQFWLLFEYPESSSAARAFALVSVLVIVISIFIFCLETLPEFREEKDFPSGIIQIINGTQDSSTHHSKVVAYLTDPFFIVETICIIWFCFEVGVRFVVCPSKSEFFNNIMNIIDIVSIIPYFVTLGTELGTTPDDDPNSGQNMSLATLRIIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAIYFAEVDEPQTQFVSIPDGFWWAVVTMTTVGYGDMCPITMGGKMVGTLCAIAGVLTIALPVPVIVSNFNYFYHRET 473
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Planmine SMEST
Match: SMESG000013562.1 (SMESG000013562.1) HSP 1 Score: 962.985 bits (2488), Expect = 0.000e+0 Identity = 470/470 (100.00%), Postives = 470/470 (100.00%), Query Frame = 1
Query: 106 MFYNQSALDSNSGSIRYGRKNKIKQKETNKDEIFDYFSSINDERAIKFKGSTPKSNSFKIIWNSFKRSLSSNDSGSEKKRRNALEYSSLRSGPFQYDLKEKVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTLEVIELPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFFNKSHCVSGAAPNFLDVFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVLVTFDCDGAKKSASLAFLRVIRLIRVFKLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHKTGRLRF 1515
MFYNQSALDSNSGSIRYGRKNKIKQKETNKDEIFDYFSSINDERAIKFKGSTPKSNSFKIIWNSFKRSLSSNDSGSEKKRRNALEYSSLRSGPFQYDLKEKVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTLEVIELPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFFNKSHCVSGAAPNFLDVFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVLVTFDCDGAKKSASLAFLRVIRLIRVFKLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHKTGRLRF
Sbjct: 1 MFYNQSALDSNSGSIRYGRKNKIKQKETNKDEIFDYFSSINDERAIKFKGSTPKSNSFKIIWNSFKRSLSSNDSGSEKKRRNALEYSSLRSGPFQYDLKEKVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTLEVIELPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFFNKSHCVSGAAPNFLDVFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVLVTFDCDGAKKSASLAFLRVIRLIRVFKLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHKTGRLRF 470
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Planmine SMEST
Match: SMESG000014198.1 (SMESG000014198.1) HSP 1 Score: 499.204 bits (1284), Expect = 1.363e-174 Identity = 235/366 (64.21%), Postives = 287/366 (78.42%), Query Frame = 1
Query: 415 INISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTLEVIELPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFFNKSHCVSGAAPNFLDVFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVLVTFDCDGAKKSASLAFLRVIRLIRVFKLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHKTGRLR 1512
IN+SG+ FE T+ L HPTTLLGD K Y+DK+ EYFFDR+RP FE+IF YYQ +KRP +VPD+IFL EL F+QIEK V+ YK +EGH E LP K ++ +W+LFE+PETS+ A+ + ++S+ FT++SI+LFCVET P F ++HCV G+APNFLD FF++ET CT WF++E R + CPSK IKD+KN +D+ A++PYYVTL NVL +F C GAK SASLAFLRVI+LIR+FKLTKHS GLQVL+ TFRASIE LGLF+VALS+ +ILFSS +YY E DS I+SIP AFWWAIITMCTVGYGD VPQ LGK+VGS CAV+GVLTLAIPVPIITENFNKFYSH+T R R
Sbjct: 48 INVSGMKFEIPTYKLKYHPTTLLGDSHKCKSYFDKRFNEYFFDRHRPTFEAIFVYYQYSCDLKRPFDVPDDIFLEELKFFQIEKEVVMKYKLEEGHVEETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKETHCVDGSAPNFLDSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTLVNVLYSFSCSGAKNSASLAFLRVIKLIRIFKLTKHSSGLQVLLKTFRASIESLGLFVVALSMLVILFSSALYYVENTYEDSDIKSIPHAFWWAIITMCTVGYGDAVPQHFLGKIVGSFCAVAGVLTLAIPVPIITENFNKFYSHRTNRNR 413
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Planmine SMEST
Match: SMESG000014206.1 (SMESG000014206.1) HSP 1 Score: 495.738 bits (1275), Expect = 3.830e-173 Identity = 234/366 (63.93%), Postives = 286/366 (78.14%), Query Frame = 1
Query: 415 INISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTLEVIELPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFFNKSHCVSGAAPNFLDVFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVLVTFDCDGAKKSASLAFLRVIRLIRVFKLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHKTGRLR 1512
IN+SG+ FE T+ L HPTTLLGD K Y+DK+ EYFFDR+RP FE+IF YYQ +KRP +V D+IFL EL F+QIEK V+ YK +EGH E LP K ++ +W+LFE+PETS+ A+ + ++S+ FT++SI+LFCVET P F ++HCV G+APNFLD FF++ET CT WF++E R + CPSK IKD+KN +D+ A++PYYVTL NVL +F C GAK SASLAFLRVI+LIR+FKLTKHS GLQVL+ TFRASIE LGLF+VALS+ +ILFSS +YY E DS I+SIP AFWWAIITMCTVGYGD VPQ LGK+VGS CAV+GVLTLAIPVPIITENFNKFYSH+T R R
Sbjct: 48 INVSGMKFEIPTYKLKYHPTTLLGDSHKCKSYFDKRFNEYFFDRHRPTFEAIFVYYQYSCDLKRPFDVLDDIFLEELKFFQIEKEVVMKYKLEEGHVEETFVLPKGKYQQKLWILFEYPETSLLAYTIGLISMIFTLISIILFCVETLPVFKETHCVDGSAPNFLDSFFLIETFCTAWFSLEFIVRLVVCPSKNAHIKDLKNTVDIIAILPYYVTLVNVLYSFSCSGAKNSASLAFLRVIKLIRIFKLTKHSSGLQVLLKTFRASIESLGLFVVALSMLVILFSSALYYVENTYEDSDIKSIPHAFWWAIITMCTVGYGDAVPQHFLGKIVGSFCAVAGVLTLAIPVPIITENFNKFYSHRTNRNR 413
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Planmine SMEST
Match: SMESG000006565.1 (SMESG000006565.1) HSP 1 Score: 475.707 bits (1223), Expect = 3.412e-165 Identity = 219/372 (58.87%), Postives = 293/372 (78.76%), Query Frame = 1
Query: 400 KEKVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTLEVIELPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFFNKSHCVSGAAPNFLDVFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVLVTFDC-DGAKKSASLAFLRVIRLIRVFKLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHKTGRLR 1512
K +V IN+SGL FETW L+ HPTTLLG P+ R ++D +R EYFFDR+R AFE IF+YY+ G KIKRP NVP+++FL+E++++++E +VI+ + D+G+ E I+LP+N + + IW+LFE+PETS A+ V ++S+ T++SI FC+ET P ++K C+ NFL FFI ET+CT WFTIE+ R +SCP+ +++KD KN++D+ A+IPYY+TL N+L + +C DG K +SLA LRVIRLIR+FKLTKHS GLQVL+LTF+AS+ GLG+FL+A+ VS++LFSSTIYY EV DS I SIPDAFWW +ITMCTVGYGD VP+ ++G++VGS CAVSGVLTLA+ VPII+ENFNKFYSHKTGR R
Sbjct: 47 KSRVRINVSGLIFETWISDLDRHPTTLLGSPTLRKQHFDSRRNEYFFDRHRQAFEGIFHYYKYGDKIKRPANVPEDVFLSEMEYFKLEPNVINGFHHDQGYVFEKIKLPSNPLLQKIWVLFEYPETSGYAYAVGIVSLLLTIMSITAFCIETIPKYSKM-CIDNKNYNFLSGFFICETICTIWFTIEMIGRLVSCPNLKEYMKDCKNVMDIVALIPYYITLANMLFSDNCIDGKKGGSSLAILRVIRLIRIFKLTKHSTGLQVLILTFQASLNGLGIFLLAMLVSMLLFSSTIYYLEVDVKDSDIASIPDAFWWCVITMCTVGYGDMVPKSLMGRIVGSFCAVSGVLTLAMAVPIISENFNKFYSHKTGRGR 417
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Planmine SMEST
Match: SMESG000020672.1 (SMESG000020672.1) HSP 1 Score: 391.734 bits (1005), Expect = 6.595e-131 Identity = 204/441 (46.26%), Postives = 282/441 (63.95%), Query Frame = 1
Query: 244 KFKGSTPKSNSFKIIWNSFKRSLS---SNDSGSEKKRRNALEYSSLRSGPFQYDLKEKVVINISGLTFETWTWILNEHPTTLLGDPSKRSMYYDKKRQEYFFDRYRPAFESIFNYYQNGGKIKRPVNVPDEIFLTELDFYQIEKSVIDAYKKDEGHTLEVIE-LPTNKIKRSIWMLFEFPETSVSAFCVAVLSVAFTVLSIVLFCVETHPFFNKSHCVSGA---------------APNFLDVFFILETVCTFWFTIEVSFRFISCPSKVKFIKDIKNIIDVAAVIPYYVTLTNVLVTFDCDGAKKSASLAFLRVIRLIRVF---KLTKHSPGLQVLMLTFRASIEGLGLFLVALSVSIILFSSTIYYAEVGNPDSQIESIPDAFWWAIITMCTVGYGDKVPQQILGKLVGSVCAVSGVLTLAIPVPIITENFNKFYSHKT 1500
K GS P ++ F ++F +S+ ++ +K NA +YD+ E+V INISGL FET L + P TLLG+ KR+ Y+D R EYFFDR RP+F++I YYQ+GG+++RPVNVP ++F E+ FY++ + I+ Y++DEG+ E I+ LP N +R +W+LFE+PE+S+ A CVA+ SV +LSIV+FC+ET P F V+ P F + FFI+ETVC WFT E+ RF S P K+ F K I N+ID+ A+IPY++TL V+ D ++ SLA LRVIRL+RVF KL++HS GLQ+L T +AS+ LGL + L +S+ILFSS +Y+AE S SIPDAFWWA++TM TVGYGD P + GKLVGS+CA++GVLT+A+PVP+I NFN FY +T
Sbjct: 11 KPSGSMPHNDFFYEKSHTFNQSMPKYPDEETPYDKVGENA-----------EYDI-ERVTINISGLRFETQLKTLGQFPNTLLGNALKRNQYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPIDVFCEEIKFYELGEEAIEKYREDEGYIKEDIKILPENPFQRKVWLLFEYPESSMGARCVAICSVFVIILSIVIFCIETLPHFKHYRIVNSTFAGTNQSAYKIEEDDIPQFSEPFFIIETVCIIWFTFELLVRFSSSPEKLTFFKTIMNLIDIVAIIPYFITLGTVIAD-DSRSQNQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASVRELGLLVFFLLISVILFSSAVYFAEADADKSYFRSIPDAFWWAVVTMTTVGYGDMRPVTVWGKLVGSLCAIAGVLTIALPVPVIVSNFNYFYHRET 438 The following BLAST results are available for this feature:
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Potassium voltage-gated channel subfamily A member 2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30019915 ID=SMED30019915|Name=Potassium voltage-gated channel subfamily A member 2|organism=Schmidtea mediterranea sexual|type=transcript|length=1623bpback to top protein sequence of SMED30019915-orf-1 >SMED30019915-orf-1 ID=SMED30019915-orf-1|Name=SMED30019915-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=471bp MFYNQSALDSNSGSIRYGRKNKIKQKETNKDEIFDYFSSINDERAIKFKGback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
|
