Rabenosyn-5

Overview
NameRabenosyn-5
Smed IDSMED30019882
Length (bp)1786
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Rabenosyn-5 (SMED30019882) t-SNE clustered cells

Violin plots show distribution of expression levels for Rabenosyn-5 (SMED30019882) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Rabenosyn-5 (SMED30019882) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Rabenosyn-5 (SMED30019882) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30019882

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 1

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
nervous systemSMED30019882SMESG000056864.1 dd_Smed_v4_6187_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Rabenosyn-5 vs. Ensembl Human
Match: RBSN (rabenosyn, RAB effector [Source:HGNC Symbol;Acc:HGNC:20759])

HSP 1 Score: 140.969 bits (354), Expect = 1.581e-34
Identity = 145/567 (25.57%), Postives = 244/567 (43.03%), Query Frame = 3 
Query:  105 ITEGFICPECMKKCVSLKNLXXXXXXXXXXXXXXPSDQSGFLGIIKKAKKTFEEILDAKDGELIFSNNLSSNTLKNENNDMDD-DPFVSHAFYEEPNIKPQPLGITVNRTEEFLKIRRTKLLRSAIETSSLILKIEKLISF-QSNASNRERKNFEQSIVEWVKDDLVPMCPMCGGKFGINSPISTYSDVPAVLSSNIEQQNTRKQSRFKTAFINFMDMEIEGSGLLIRKKHHCRLCGCVICAHCSYILSAGEASKLVNAINSRFELKESILEESRKILW-KNDSQNSLDSIKSKIKTQTVYSIRCCGNCKSLIEAKWNQLERRVCDSEIVDLYEELMENRNKVSQLIPEYNTMCQSLCLGETEYSYQRANELRSEIVQFCQKIDAIGNKFKSRTTTNGSEREAT---LVKSIYRNTFLFLQNNFATLKQLPQEDKLEEIVNQRLIE------IKKKAATMQKNRSPEIEKYLV-KSNNDD-----SGWAPTIPSNCGYHNEGHNRNTNNPFECDSTDSNTEENTRLTALALQMENVRQYIELAHQAKKVQEVKMLQNNMLDLKLEYD 1751
            + EGF+CP C+K   S   L  H+++ H  +      Q     +++KAKK  + +L  ++G+    +   S T   E+      DP++          +PQ LG   +   +F K R  ++    +E + LI+++EKL +F ++N  + + +  E+S+V WV D  VP CP CG KF I +                                               ++HHCRLCG ++C  C  ++S   A+KL +A         S  +    +   +  S +S+ S+ S +  +    IRCC +CK  +  +  Q++ +    +IV LYE+L     KV Q  PEY  M  SL  GET YS + A++LR E+ +  + IDA+  K  +           +   L + I  +  LF+Q     L  LP +++ EE+  +R  E      ++++AA   + R  E +  L  ++ N +      G AP              R              +E++     L  Q+ N+  +I  A  A ++ EV+ LQ N+  L+ EYD
Sbjct:   10 VREGFLCPLCLKDLQSFYQLHSHYEEEHSGEDRDVKGQ--IKSLVQKAKKAKDRLL-KREGD----DRAESGTQGYESFSYGGVDPYM---------WEPQELGAVRSHLSDFKKHRAARIDHYVVEVNKLIIRLEKLTAFDRTNTESAKIRAIEKSVVPWVNDQDVPFCPDCGNKFSIRN-----------------------------------------------RRHHCRLCGSIMCKKCMELISLPLANKLTSASKESLSTHTSPSQSPNSVHGSRRGSISSMSSVSSVLDEKDDDRIRCCTHCKDTLLKREQQIDEKEHTPDIVKLYEKLRLCMEKVDQKAPEYIRMAASLNAGETTYSLEHASDLRVEVQKVYELIDALSKKILTLGLNQDPPPHPSNLRLQRMIRYSATLFVQEKLLGLMSLPTKEQFEELKKKRKEEMERKRAVERQAALESQRRLEERQSGLASRAANGEVASLRRGPAPL-------------RKAEGWLPLSGGQGQSEDS---DPLLQQIHNITSFIRQAKAAGRMDEVRTLQENLRQLQDEYD 497
[Close]
BLAST of Rabenosyn-5 vs. Ensembl Human
Match: RBSN (rabenosyn, RAB effector [Source:HGNC Symbol;Acc:HGNC:20759])

HSP 1 Score: 140.969 bits (354), Expect = 1.581e-34
Identity = 145/567 (25.57%), Postives = 244/567 (43.03%), Query Frame = 3 
Query:  105 ITEGFICPECMKKCVSLKNLXXXXXXXXXXXXXXPSDQSGFLGIIKKAKKTFEEILDAKDGELIFSNNLSSNTLKNENNDMDD-DPFVSHAFYEEPNIKPQPLGITVNRTEEFLKIRRTKLLRSAIETSSLILKIEKLISF-QSNASNRERKNFEQSIVEWVKDDLVPMCPMCGGKFGINSPISTYSDVPAVLSSNIEQQNTRKQSRFKTAFINFMDMEIEGSGLLIRKKHHCRLCGCVICAHCSYILSAGEASKLVNAINSRFELKESILEESRKILW-KNDSQNSLDSIKSKIKTQTVYSIRCCGNCKSLIEAKWNQLERRVCDSEIVDLYEELMENRNKVSQLIPEYNTMCQSLCLGETEYSYQRANELRSEIVQFCQKIDAIGNKFKSRTTTNGSEREAT---LVKSIYRNTFLFLQNNFATLKQLPQEDKLEEIVNQRLIE------IKKKAATMQKNRSPEIEKYLV-KSNNDD-----SGWAPTIPSNCGYHNEGHNRNTNNPFECDSTDSNTEENTRLTALALQMENVRQYIELAHQAKKVQEVKMLQNNMLDLKLEYD 1751
            + EGF+CP C+K   S   L  H+++ H  +      Q     +++KAKK  + +L  ++G+    +   S T   E+      DP++          +PQ LG   +   +F K R  ++    +E + LI+++EKL +F ++N  + + +  E+S+V WV D  VP CP CG KF I +                                               ++HHCRLCG ++C  C  ++S   A+KL +A         S  +    +   +  S +S+ S+ S +  +    IRCC +CK  +  +  Q++ +    +IV LYE+L     KV Q  PEY  M  SL  GET YS + A++LR E+ +  + IDA+  K  +           +   L + I  +  LF+Q     L  LP +++ EE+  +R  E      ++++AA   + R  E +  L  ++ N +      G AP              R              +E++     L  Q+ N+  +I  A  A ++ EV+ LQ N+  L+ EYD
Sbjct:   10 VREGFLCPLCLKDLQSFYQLHSHYEEEHSGEDRDVKGQ--IKSLVQKAKKAKDRLL-KREGD----DRAESGTQGYESFSYGGVDPYM---------WEPQELGAVRSHLSDFKKHRAARIDHYVVEVNKLIIRLEKLTAFDRTNTESAKIRAIEKSVVPWVNDQDVPFCPDCGNKFSIRN-----------------------------------------------RRHHCRLCGSIMCKKCMELISLPLANKLTSASKESLSTHTSPSQSPNSVHGSRRGSISSMSSVSSVLDEKDDDRIRCCTHCKDTLLKREQQIDEKEHTPDIVKLYEKLRLCMEKVDQKAPEYIRMAASLNAGETTYSLEHASDLRVEVQKVYELIDALSKKILTLGLNQDPPPHPSNLRLQRMIRYSATLFVQEKLLGLMSLPTKEQFEELKKKRKEEMERKRAVERQAALESQRRLEERQSGLASRAANGEVASLRRGPAPL-------------RKAEGWLPLSGGQGQSEDS---DPLLQQIHNITSFIRQAKAAGRMDEVRTLQENLRQLQDEYD 497
[Close]
BLAST of Rabenosyn-5 vs. Ensembl Human
Match: RBSN (rabenosyn, RAB effector [Source:HGNC Symbol;Acc:HGNC:20759])

HSP 1 Score: 53.5286 bits (127), Expect = 8.465e-8
Identity = 37/119 (31.09%), Postives = 57/119 (47.90%), Query Frame = 3 
Query: 1047 NQLERRVCDSEIVDLYEELMENRNKVSQLIPEYNTMCQSLCLGETEYSYQRANELRSEIVQFCQKIDAIGNKFKSRTTTNGSEREAT---LVKSIYRNTFLFLQNNFATLKQLPQEDKL 1394
             Q++ +    +IV LYE+L     KV Q  PEY  M  SL  GET YS + A++LR E+ +  + IDA+  K  +           +   L + I  +  LF+Q     L  LP +++ 
Sbjct:    9 QQIDEKEHTPDIVKLYEKLRLCMEKVDQKAPEYIRMAASLNAGETTYSLEHASDLRVEVQKVYELIDALSKKILTLGLNQDPPPHPSNLRLQRMIRYSATLFVQEKLLGLMSLPTKEQF 127
[Close]
BLAST of Rabenosyn-5 vs. Ensembl Celegans
Match: rabs-5 (RABenoSyn (Trafficking protein) homolog [Source:UniProtKB/TrEMBL;Acc:Q9N3Y4])

HSP 1 Score: 110.538 bits (275), Expect = 2.750e-25
Identity = 138/603 (22.89%), Postives = 251/603 (41.63%), Query Frame = 3 
Query:  105 ITEGFICPECMKKCVSLKNLXXXXXXXXXXXXXXPSDQSGFL-----GIIKKAKKTFEEILDAKDGELIFSNNLSSNTLKNENNDMDDDPFVSHAFYEEPNIKPQPL-------GITVNRTEEFLKIRRTKLLRSAIETSSLILKIEKLISFQSNASNR-ERKNFEQSIVEWVKDDLVPMCPMCGGKFGINSPISTYSDVPAVLSSNIEQQNTRKQSRFKTAFINFMDMEIEGSGLLIRKKHHCRLCGCVICAHCSYILSAGEASKLVNAIN------------SRFELKESIL--EESRKILWKNDSQNSLDSIKSKI--KTQTVYS--------------------IRCCGNCKSLIEAKWNQLERRVCDSEIVDLYEELMENRNKVSQLIPEYNTMCQSLCLGETEYSYQRANELRSEIVQFCQKIDAIGNKF-KSRTTTNGSEREATLVKSIYRNTFLFLQNNFATLKQLPQEDKLEEIV----NQRLIEIKKKAATMQKNRS--PEIEKYLVKSNNDDSGWAPTIPSNCGYHNEGHNRNTNNPFECDSTDSNTEENTRLTALALQMENVRQYIELAHQAKKVQEVKMLQNNMLDLKLE 1745
            + +GFICP CM+     + L  H +  H ++    SD +G       G   KAK+  ++ LDAK      ++N+ +   +     ++  P         P I P+PL       G   ++T EFL  R   +   A+ T+ LI+++++LI+      +  +RK FE+ +V W+ D     CP+C  +FG                                               L R++HHCRLCG V+C  CS  LS   A  L ++ N            +  E ++ +L  EE+ +  + + SQ S+D +K  +    Q V+S                    +R C  C   +  + +Q++++    E V  Y+ +     +V  L+P Y  +  SL  GE+ YS++   ELRS+ ++  + ID +  K  +       S +E  L K+I       LQ     ++ LP  ++   ++     +R  +  +   T+ K  S  P++++     N+  S  +   PS+        + + +  FE  S + +T +      L  Q E +R+++  A    K+ E+ +L+ N+ +++ E
Sbjct:   17 VRQGFICPFCMEDFGEYERLICHVENDHPEEDS--SDLAGMFVSNVKGFFDKAKRGIQK-LDAKKSIADLASNVETEFTETTEKLVERAPL--------PRI-PKPLPPDEILPGTRRSKTREFLSTRELNINEVAVRTNMLIIRLDRLINGGPKDKDPVKRKEFEREVVPWLDDAEAVCCPLCASRFG-----------------------------------------------LTRRRHHCRLCGRVLCHSCSKFLSFDTAKTLTSSSNPLGDTHIIVEEPNTVENEQELLQPEENGRRSFFSLSQKSMDKMKRAMAGAVQKVHSAATGEEIIAGALNEQDLSEHMRVCNLCLRDLHFRESQMDKKE-PPEFVQQYDLMKVMIEEVKNLVPTYVRVVTSLKNGESVYSHKHGEELRSKCLEIQKSIDYVSKKIAEGANDKPNSAKEQQLRKNIRLYAVQALQGLIGQMESLPTAEECSNLIIKRKERRAKDFARVNRTVMKMSSSMPQLQEQHSHLNSTSSVSSFGGPSSIDDGWSAEDNDLSRVFEPSSIEDDTIQTDH--PLYEQREQLRKFLFQASATGKLDEMDILERNLKEIEEE 557
[Close]
BLAST of Rabenosyn-5 vs. Ensembl Celegans
Match: rabs-5 (RABenoSyn (Trafficking protein) homolog [Source:UniProtKB/TrEMBL;Acc:Q9N3Y4])

HSP 1 Score: 108.612 bits (270), Expect = 1.034e-24
Identity = 140/604 (23.18%), Postives = 254/604 (42.05%), Query Frame = 3 
Query:  105 ITEGFICPECMKKCVSLKNLXXXXXXXXXXXXXXPSDQSGFL-----GIIKKAKKTFEEILDAKDGELIFSNNLSSNTLKNENNDMDDDPFVSHAFYEEPNIKPQPL-------GITVNRTEEFLKIRRTKLLRSAIETSSLILKIEKLISFQSNASNR-ERKNFEQSIVEWVKDDLVPMCPMCGGKFGINSPISTYSDVPAVLSSNIEQQNTRKQSRFKTAFINFMDMEIEGSGLLIRKKHHCRLCGCVICAHCSYILSAGEASKLVNAIN------------SRFELKESIL--EESRKILWKNDSQNSLDSIKSKI--KTQTVYS--------------------IRCCGNCKSLIEAKWNQLERRVCDSEIVDLYEELMENRNKVSQLIPEYNTMCQSLCLGETEYSYQRANELRSEIVQFCQKIDAIGNKF-KSRTTTNGSEREATLVKSIYRNTFLFLQNNFATLKQLPQEDKLEEIV----NQRLIEIKKKAATMQKNRS--PEIEKYLVKSNNDDSGWAPTIPSNCGYHNEGHNRNTNN-PFECDSTDSNTEENTRLTALALQMENVRQYIELAHQAKKVQEVKMLQNNMLDLKLE 1745
            + +GFICP CM+     + L  H +  H ++    SD +G       G   KAK+  ++ LDAK      ++N+ +   +     ++  P         P I P+PL       G   ++T EFL  R   +   A+ T+ LI+++++LI+      +  +RK FE+ +V W+ D     CP+C  +FG                                               L R++HHCRLCG V+C  CS  LS   A  L ++ N            +  E ++ +L  EE+ +  + + SQ S+D +K  +    Q V+S                    +R C  C   +  + +Q++++    E V  Y+ +     +V  L+P Y  +  SL  GE+ YS++   ELRS+ ++  + ID +  K  +       S +E  L K+I       LQ     ++ LP  ++   ++     +R  +  +   T+ K  S  P++++     N+  S  +   PS+    ++G +   N+  FE  S + +T +      L  Q E +R+++  A    K+ E+ +L+ N+ +++ E
Sbjct:   17 VRQGFICPFCMEDFGEYERLICHVENDHPEEDS--SDLAGMFVSNVKGFFDKAKRGIQK-LDAKKSIADLASNVETEFTETTEKLVERAPL--------PRI-PKPLPPDEILPGTRRSKTREFLSTRELNINEVAVRTNMLIIRLDRLINGGPKDKDPVKRKEFEREVVPWLDDAEAVCCPLCASRFG-----------------------------------------------LTRRRHHCRLCGRVLCHSCSKFLSFDTAKTLTSSSNPLGDTHIIVEEPNTVENEQELLQPEENGRRSFFSLSQKSMDKMKRAMAGAVQKVHSAATGEEIIAGALNEQDLSEHMRVCNLCLRDLHFRESQMDKKE-PPEFVQQYDLMKVMIEEVKNLVPTYVRVVTSLKNGESVYSHKHGEELRSKCLEIQKSIDYVSKKIAEGANDKPNSAKEQQLRKNIRLYAVQALQGLIGQMESLPTAEECSNLIIKRKERRAKDFARVNRTVMKMSSSMPQLQEQHSHLNSTSSVSSFGGPSSI---DDGWSAEDNDLVFEPSSIEDDTIQTDH--PLYEQREQLRKFLFQASATGKLDEMDILERNLKEIEEE 555
[Close]
BLAST of Rabenosyn-5 vs. Ensembl Fly
Match: Rbsn-5 (gene:FBgn0261064 transcript:FBtr0079581)

HSP 1 Score: 107.457 bits (267), Expect = 2.674e-24
Identity = 124/553 (22.42%), Postives = 219/553 (39.60%), Query Frame = 3 
Query:  105 ITEGFICPECMKKCVSLKNLXXXXXXXXXXXXXXPSDQSGFLGIIKKAKKTFEEILDAKDGELIFSNNLSSNTLKNENNDMDDDPFVSHAFYEEPNI-----KPQPLGITVNRTEEFLKIRRTKLLRSAIETSSLILKIEKLISFQSNASNRERKNFEQSIVEWVKDDLVPMCPMCGGKFGINSPISTYSDVPAVLSSNIEQQNTRKQSRFKTAFINFMDMEIEGSGLLIRKKHHCRLCGCVICAHCSYILSAGEASKLVNAINSRFELKESILEESRKILWKNDSQNSLDSIKSKIKTQTVYSIRCCGNCKSLIEAKWNQLERRVCDSEIVDLYEELMENRNKVSQLIPEYNTMCQSLCLGETEYSYQRANELRSEIVQFCQKIDAIGNKFKSRTTTNGSEREATLVKSIYRNTFLFLQNNFATLKQLPQEDKLEEIVNQRLIEIKKKAATMQKNRSPEIEKYLVKSNNDDSGWAPTIPS-NCGYHNEGHNRNTNNPFECDSTDSNTEENTRLTALALQMENVRQYIELAHQAKKVQEVKMLQNNMLDLKLE 1745
            I EGF+CP C      LK++            E       F  I  KAKK      + + G  + S   SS++   +N + + D           N+     + QP G   +  E F  IR  +L R A ET+ LI+++ +L+     A + +R+  EQ  V W+    V +CP C   F I                                                R++HHCRLCG ++C  CS  L   +A +L +   +R E  + +                          Q   +IR C +C  L++ + +  E R C   +V +YE++ + + +V+  +  Y  +  SL  G+T ++   A  LR +I Q  + +D    +  +     GS RE  L K+I       ++    +L  LP+E  + ++  +R +E +++  T Q+      E+  + +N  + G    +P    G   +G +  + N +      S +  +  L     Q+  ++ YI+ A Q    + V+ L+ N+ +L+ E
Sbjct:   19 ILEGFLCPICR---ADLKSIDVLTDHFARQHAEEEDALKSFKDIFTKAKKKILNPFEDEKGASVSSPAGSSSSAAGKNPNGNGDRNGPSNARSRLNVFNYMARQQP-GAECSHFEYFQSIRNPRLERYASETNKLIIRLHRLLK-DLPADSVQRRQHEQQTVAWLDGSSVKLCPSCAKSFHI-----------------------------------------------ARRQHHCRLCGGIMCNDCSKFLPLEDAMQLASLSTTRSEPLQQL-------------------------HQHENAIRLCEHCLWLLDTRKDMHESRTCRPLLVQVYEQIRQLQKEVTPDLDMYLKIINSLNEGDTIFTLADAGALRGKIGQVAEAMDMRSKRILAIFCEPGS-REEALKKAIRLGCIQAIKERMLSLPPLPEESHIRQMQERRRMETEQRILTEQRMAMEAYERNNMAANQSNVG----VPGPESGSFAQGSDLQSLNNWSAPQAASKSSLDDPLIE---QINIIKGYIKQARQDMNFEVVETLELNLRELQRE 486
[Close]
BLAST of Rabenosyn-5 vs. Ensembl Zebrafish
Match: rbsn (rabenosyn, RAB effector [Source:ZFIN;Acc:ZDB-GENE-100525-1])

HSP 1 Score: 141.354 bits (355), Expect = 1.763e-35
Identity = 146/575 (25.39%), Postives = 236/575 (41.04%), Query Frame = 3 
Query:  105 ITEGFICPECMKKCVSLKNLXXXXXXXXXXXXXXPSDQSGFLGIIKKAKKTFEEILDAKDGELIFSNNLSSNTLKNENNDMDDDPFVSHAFYEEPNI-KPQPLGITVNRTEEFLKIRRTKLLRSAIETSSLILKIEKLISF-QSNASNRERKNFEQSIVEWVKDDLVPMCPMCGGKFGINSPISTYSDVPAVLSSNIEQQNTRKQSRFKTAFINFMDMEIEGSGLLIRKKHHCRLCGCVICAHCSYILSAGEASKLVNAINSRFELKESILEESRKILWKNDSQNSLDSIKSKIKTQTVYS--------------------IRCCGNCKSLIEAKWNQLERRVCDSEIVDLYEELMENRNKVSQLIPEYNTMCQSLCLGETEYSYQRANELRSEIVQFCQKIDAIGNKFKS---RTTTNGSEREATLVKSIYRNTFLFLQNNFATLKQLPQEDKLEEIVNQRLIEIKKKAATMQKNRSPEIEKYLVKSNNDDSGWAPTIPSNCGYHNEGHNRNTNNPFECDSTDSNTEENTRLTALALQMENVRQYIELAHQAKKVQEVKMLQNNMLDLKLEYDA 1754
            + EGF+CP C K   S   LQDH+++ H           G L  + +  K  ++ L  +DG              +E  D   + F       +P + +PQ LG T +  + F K R  ++    IE +  I+++EKL SF ++N    + ++ E+S+V WV D  VP CP CGGKF + +                                               ++HHCRLCG ++C  C+  +    A KL +               +R+ LW   S  S  S    +  QT                       +RCC +C   +     +LE +    +IV LYE L    +KV    PEY  M +SL  GE  YS +    LR EI ++ + ID +  K  +   +       +   L + +     LF+Q     L  LP ++K EE+  +R +E +K+A   Q+ R   +E +  +  N+ +   PT+  N    +    R T        +D+ +E++     L  Q+EN+  ++  A  A +  EV ML+ N+  L+ E+DA
Sbjct:   15 VKEGFLCPLCFKDLQSFYQLQDHYEEEHAGDSRHVG---GQLKNLVQKAKKAKDKLLKRDG--------------DERTDSSYESFYYGGV--DPYMWEPQELGATRSHLDYFKKQRAARIDHYVIEVNKCIIRLEKLTSFDRTNMDAAQIRSLEKSVVSWVNDQDVPFCPDCGGKFNLRN-----------------------------------------------RRHHCRLCGSIMCRKCTEFVPLPMAYKLTSG--------------TREALWAPGSGGSPVSTGQAVVQQTSRRGSISSISSVTSVLEEKDEDRVRCCHHCMDALLRHQRKLEEKDHVPDIVKLYERLRTCMDKVEAKAPEYTRMAESLNAGEKTYSLESTAALRMEIQKYYELIDVLSKKILTLGLKEELQPHPKALQLQRMVRYTATLFIQEKLLGLTSLPTKEKYEELKEKRRVEQEKRA---QQERQVSLESHKRRLENEKN--RPTVSVN---GDVAAPRVTKAGGWLPQSDTRSEQD---DPLLQQIENIESFLRQARSANRSDEVCMLEENLRQLQDEFDA 498
[Close]
BLAST of Rabenosyn-5 vs. Ensembl Zebrafish
Match: rbsn (rabenosyn, RAB effector [Source:ZFIN;Acc:ZDB-GENE-100525-1])

HSP 1 Score: 140.584 bits (353), Expect = 1.165e-34
Identity = 147/584 (25.17%), Postives = 239/584 (40.92%), Query Frame = 3 
Query:  105 ITEGFICPECMKKCVSLKNLXXXXXXXXXXXXXXPSDQSGFLGIIKKAKKTFEEILDAKDGELIFSNNLSSNTLKNENNDMDDDPFVSHAFYEEPNIKPQPLGITVNRTEEFLKIRRTKLLRSAIETSSLILKIEKLISF-QSNASNRERKNFEQSIVEWVKDDLVPMCPMCGGKFGINSPISTYSDVPAVLSSNIEQQNTRKQSRFKTAFINFMDMEIEGSGLLIRKKHHCRLCGCVICAHCSYILSAGEASKLVNAINSRFELKESILEESRKILWKNDSQNSLDSIKSKIKTQTVYS--------------------IRCCGNCKSLIEAKWNQLERRVCDSEIVDLYEELMENRNKVSQLIPEYNTMCQSLCLGETEYSYQRANELRSEIVQFCQKIDAIGNKFKS---RTTTNGSEREATLVKSIYRNTFLFLQNNFATLKQLPQEDKLEEIVNQRLIEIKKKAATMQKNRSPEIEKYLVKSNNDDSGWAPTIPSNCGYHNEGHNRNTNNPFECDSTDSNTEENTRLTALALQMENVRQYIELAHQAKKVQEVKMLQNNMLDLKLEYDALRKKLKI*IT 1784
            + EGF+CP C K   S   LQDH+++ H           G L  + +  K  ++ L  +DG+    ++  S            DP++          +PQ LG T +  + F K R  ++    IE +  I+++EKL SF ++N    + ++ E+S+V WV D  VP CP CGGKF + +                                               ++HHCRLCG ++C  C+  +    A KL +               +R+ LW   S  S  S    +  QT                       +RCC +C   +     +LE +    +IV LYE L    +KV    PEY  M +SL  GE  YS +    LR EI ++ + ID +  K  +   +       +   L + +     LF+Q     L  LP ++K EE+  +R +E +K+A   Q+ R   +E +  +  N+ +   PT+  N         R T        +D+ +E++     L  Q+EN+  ++  A  A +  EV ML+ N+  L+ E+DA +    I I+
Sbjct:   15 VKEGFLCPLCFKDLQSFYQLQDHYEEEHAGDSRH---VGGQLKNLVQKAKKAKDKLLKRDGDERTDSSYESFYYGGV------DPYM---------WEPQELGATRSHLDYFKKQRAARIDHYVIEVNKCIIRLEKLTSFDRTNMDAAQIRSLEKSVVSWVNDQDVPFCPDCGGKFNLRN-----------------------------------------------RRHHCRLCGSIMCRKCTEFVPLPMAYKLTSG--------------TREALWAPGSGGSPVSTGQAVVQQTSRRGSISSISSVTSVLEEKDEDRVRCCHHCMDALLRHQRKLEEKDHVPDIVKLYERLRTCMDKVEAKAPEYTRMAESLNAGEKTYSLESTAALRMEIQKYYELIDVLSKKILTLGLKEELQPHPKALQLQRMVRYTATLFIQEKLLGLTSLPTKEKYEELKEKRRVEQEKRA---QQERQVSLESHKRRLENEKN--RPTVSVNGDV---AAPRVTKAGGWLPQSDTRSEQD---DPLLQQIENIESFLRQARSANRSDEVCMLEENLRQLQDEFDAQQTSRAIEIS 508
[Close]
BLAST of Rabenosyn-5 vs. Ensembl Xenopus
Match: RBSN (rabenosyn, RAB effector [Source:NCBI gene;Acc:100496168])

HSP 1 Score: 151.369 bits (381), Expect = 5.081e-38
Identity = 145/560 (25.89%), Postives = 241/560 (43.04%), Query Frame = 3 
Query:  105 ITEGFICPECMKKCVSLKNLXXXXXXXXXXXXXXPSDQSGFLGIIKKAKKTFEEILDAKDGELIFSNNLSSNTLKNENNDMDDDPFVSHAFYEEPNIKPQPLGITVNRTEEFLKIRRTKLLRSAIETSSLILKIEKLISF-QSNASNRERKNFEQSIVEWVKDDLVPMCPMCGGKFGINSPISTYSDVPAVLSSNIEQQNTRKQSRFKTAFINFMDMEIEGSGLLIRKKHHCRLCGCVICAHCSYILSAGEASKLVNAINSRFELKES--ILEESRKILWKNDSQNSLDSIKSKIKTQTVYSIRCCGNCKSLIEAKWNQLERRVCDSEIVDLYEELMENRNKVSQLIPEYNTMCQSLCLGETEYSYQRANELRSEIVQFCQKIDAIGNKFKS---RTTTNGSEREATLVKSIYRNTFLFLQNNFATLKQLPQEDKLEEIVNQRLIEIKKKAATMQKNRSPEIEKYLVKSNNDDSGWAPTIPSNCGYHN-----EGHNRNTNNPFECDSTDSNTEENTRLTALALQMENVRQYIELAHQAKKVQEVKMLQNNMLDLKLEYD 1751
            + EGF+CP C+K   S   LQ H+++ H +      D  G L  + +  K  +  L  +DG             + E    +     S+   +     PQ +G   +    F + R  ++    +E + LI+++EKL SF + N  + + +  E+S+V WV D  VP CP CG KF I +                                               ++HHCRLCG ++C  C+ +++   ASKL +A         S  +   S     +  S +SL S+ S ++ +    IRCC +CK  +  +  QL+ +    EIV  Y++L     KV +  PEY  M QS+  GET Y+    N LR E+ ++ + IDA+  K  +           +   L K +  +  LF+Q     L  LP ++  EE+  +R  E ++K    ++  +P +  +   +++D      T+P   G+ N     EG    + +P   + +D           L  Q+EN+  YI  A  A +V EV+ML++N+  L+ EYD
Sbjct:   10 VREGFLCPLCLKDLQSFYQLQSHYEEEHSEDR----DVKGQLKSLVQIAKKAKNKLLKRDG-----------GERAEGGSQERYEAYSYGGVDPCMWDPQEIGAMRSHLSNFKRHRAARIDHYVVEVNKLIIRLEKLTSFDRVNTESVKIRAIEKSVVSWVSDQDVPFCPDCGNKFTIRN-----------------------------------------------RRHHCRLCGSIMCKRCTELITLPFASKLTSASKHSLSAHGSPNLSPSSSAQTSRRGSISSLSSVSSVLEEKDDDKIRCCHHCKDTLLKREQQLDEKEHTPEIVKYYQKLRSCMEKVDEKAPEYIKMAQSINAGETTYNLDHTNNLRVELQKYYELIDALSKKILTLGMNEEPKPHPKTQQLQKMVRYSATLFVQEKLLGLMSLPTKEIYEELKQKRRQENEQKLQRERQVSNPIVIYHSATASSD------TVPDPTGFSNLIRKVEGWLPTSGHPRNREMSD----------PLLQQIENITSYIRQAKDAGRVDEVQMLEDNLRQLQEEYD 491
[Close]
BLAST of Rabenosyn-5 vs. Ensembl Xenopus
Match: RBSN (rabenosyn, RAB effector [Source:NCBI gene;Acc:100496168])

HSP 1 Score: 148.288 bits (373), Expect = 3.926e-37
Identity = 149/571 (26.09%), Postives = 236/571 (41.33%), Query Frame = 3 
Query:  105 ITEGFICPECMKKCVSLKNLXXXXXXXXXXXXXXPSDQSGFLGIIKKAKKTFEEILDAKDGELIFSNNLSSNTLKNENNDMDDDPFVSHAFYEEPNIKPQPLGITVNRTEEFLKIRRTKLLRSAIETSSLILKIEKLISF-QSNASNRERKNFEQSIVEWVKDDLVPMCPMCGGKFGINSPISTYSDVPAVLSSNIEQQNTRKQSRFKTAFINFMDMEIEGSGLLIRKKHHCRLCGCVICAHCSYILSAGEASKLVNAINSRFELKES--ILEESRKILWKNDSQNSLDSIKSKIKTQTVYSIRCCGNCKSLIEAKWNQLERRVCDSEIVDLYEELMENRNKVSQLIPEYNTMCQSLCLGETEYSYQRANELRSEIVQFCQKIDAIGNKFKS---RTTTNGSEREATLVKSIYRNTFLFLQNNFATLKQLPQEDKLEEIVNQRLIEIKKKAATMQKNRSPEIEKYLVKSNND--------------DSGWAPTIPSNCGYHNEGH--NRNTNNPFECDSTDSNTEENTRLTALALQMENVRQYIELAHQAKKVQEVKMLQNNMLDLKLEYD 1751
            + EGF+CP C+K   S   LQ H+++ H +      D  G L  + +  K  +  L  +DG             + E    +     S+   +     PQ +G   +    F + R  ++    +E + LI+++EKL SF + N  + + +  E+S+V WV D  VP CP CG KF I +                                               ++HHCRLCG ++C  C+ +++   ASKL +A         S  +   S     +  S +SL S+ S ++ +    IRCC +CK  +  +  QL+ +    EIV  Y++L     KV +  PEY  M QS+  GET Y+    N LR E+ ++ + IDA+  K  +           +   L K +  +  LF+Q     L  LP ++  EE+  +R  E ++K   +Q+ R  E +K       D                GW PT          GH  NR  ++P                  L  Q+EN+  YI  A  A +V EV+ML++N+  L+ EYD
Sbjct:   10 VREGFLCPLCLKDLQSFYQLQSHYEEEHSEDR----DVKGQLKSLVQIAKKAKNKLLKRDG-----------GERAEGGSQERYEAYSYGGVDPCMWDPQEIGAMRSHLSNFKRHRAARIDHYVVEVNKLIIRLEKLTSFDRVNTESVKIRAIEKSVVSWVSDQDVPFCPDCGNKFTIRN-----------------------------------------------RRHHCRLCGSIMCKRCTELITLPFASKLTSASKHSLSAHGSPNLSPSSSAQTSRRGSISSLSSVSSVLEEKDDDKIRCCHHCKDTLLKREQQLDEKEHTPEIVKYYQKLRSCMEKVDEKAPEYIKMAQSINAGETTYNLDHTNNLRVELQKYYELIDALSKKILTLGMNEEPKPHPKTQQLQKMVRYSATLFVQEKLLGLMSLPTKEIYEELKQKRRQENEQK---LQRERQAEAQKAGDDKKRDVRNGGLSPSGQIRKVEGWLPT---------SGHPRNREMSDP------------------LLQQIENITSYIRQAKDAGRVDEVQMLEDNLRQLQEEYD 488
[Close]
BLAST of Rabenosyn-5 vs. Ensembl Xenopus
Match: RBSN (rabenosyn, RAB effector [Source:NCBI gene;Acc:100496168])

HSP 1 Score: 148.288 bits (373), Expect = 6.809e-37
Identity = 149/571 (26.09%), Postives = 236/571 (41.33%), Query Frame = 3 
Query:  105 ITEGFICPECMKKCVSLKNLXXXXXXXXXXXXXXPSDQSGFLGIIKKAKKTFEEILDAKDGELIFSNNLSSNTLKNENNDMDDDPFVSHAFYEEPNIKPQPLGITVNRTEEFLKIRRTKLLRSAIETSSLILKIEKLISF-QSNASNRERKNFEQSIVEWVKDDLVPMCPMCGGKFGINSPISTYSDVPAVLSSNIEQQNTRKQSRFKTAFINFMDMEIEGSGLLIRKKHHCRLCGCVICAHCSYILSAGEASKLVNAINSRFELKES--ILEESRKILWKNDSQNSLDSIKSKIKTQTVYSIRCCGNCKSLIEAKWNQLERRVCDSEIVDLYEELMENRNKVSQLIPEYNTMCQSLCLGETEYSYQRANELRSEIVQFCQKIDAIGNKFKS---RTTTNGSEREATLVKSIYRNTFLFLQNNFATLKQLPQEDKLEEIVNQRLIEIKKKAATMQKNRSPEIEKYLVKSNND--------------DSGWAPTIPSNCGYHNEGH--NRNTNNPFECDSTDSNTEENTRLTALALQMENVRQYIELAHQAKKVQEVKMLQNNMLDLKLEYD 1751
            + EGF+CP C+K   S   LQ H+++ H +      D  G L  + +  K  +  L  +DG             + E    +     S+   +     PQ +G   +    F + R  ++    +E + LI+++EKL SF + N  + + +  E+S+V WV D  VP CP CG KF I +                                               ++HHCRLCG ++C  C+ +++   ASKL +A         S  +   S     +  S +SL S+ S ++ +    IRCC +CK  +  +  QL+ +    EIV  Y++L     KV +  PEY  M QS+  GET Y+    N LR E+ ++ + IDA+  K  +           +   L K +  +  LF+Q     L  LP ++  EE+  +R  E ++K   +Q+ R  E +K       D                GW PT          GH  NR  ++P                  L  Q+EN+  YI  A  A +V EV+ML++N+  L+ EYD
Sbjct:   70 VREGFLCPLCLKDLQSFYQLQSHYEEEHSEDR----DVKGQLKSLVQIAKKAKNKLLKRDG-----------GERAEGGSQERYEAYSYGGVDPCMWDPQEIGAMRSHLSNFKRHRAARIDHYVVEVNKLIIRLEKLTSFDRVNTESVKIRAIEKSVVSWVSDQDVPFCPDCGNKFTIRN-----------------------------------------------RRHHCRLCGSIMCKRCTELITLPFASKLTSASKHSLSAHGSPNLSPSSSAQTSRRGSISSLSSVSSVLEEKDDDKIRCCHHCKDTLLKREQQLDEKEHTPEIVKYYQKLRSCMEKVDEKAPEYIKMAQSINAGETTYNLDHTNNLRVELQKYYELIDALSKKILTLGMNEEPKPHPKTQQLQKMVRYSATLFVQEKLLGLMSLPTKEIYEELKQKRRQENEQK---LQRERQAEAQKAGDDKKRDVRNGGLSPSGQIRKVEGWLPT---------SGHPRNREMSDP------------------LLQQIENITSYIRQAKDAGRVDEVQMLEDNLRQLQEEYD 548
[Close]
BLAST of Rabenosyn-5 vs. Ensembl Xenopus
Match: RBSN (rabenosyn, RAB effector [Source:NCBI gene;Acc:100496168])

HSP 1 Score: 145.591 bits (366), Expect = 1.464e-36
Identity = 148/573 (25.83%), Postives = 239/573 (41.71%), Query Frame = 3 
Query:  105 ITEGFICPECMKKCVSLKNLXXXXXXXXXXXXXXPSDQSGFLGIIKKAKKTFEEILDAKDGELIFSNNLSSNTLKNENNDMDDDPFVSHAFYEEPNIKPQPLGITVNRTEEFLKIRRTKLLRSAIETSSLILKIEKLISF-QSNASNRERKNFEQSIVEWVKDDLVPMCPMCGGKFGINSPISTYSDVPAVLSSNIEQQNTRKQSRFKTAFINFMDMEIEGSGLLIRKKHHCRLCGCVICAHCSYILSAGEASKLVNAINSRFELKES--ILEESRKILWKNDSQNSLDSIKSKIKTQTVYSIRCCGNCKSLIEAKWNQLERRVCDSEIVDLYEELMENRNKVSQLIPEYNTMCQSLCLGETEYSYQRANELRSEIVQFCQKIDAIGNKFKSRTTTNGSE---REATLVKSIYRNTFLFLQNNFATLKQLPQEDKLEEIVNQRLIEIKKKAATMQK-------NRSPE---------IEKYLVKSNNDDSGWAPTIPSNCGYHNEGH--NRNTNNPFECDSTDSNTEENTRLTALALQMENVRQYIELAHQAKKVQEVKMLQNNMLDLKLEYD 1751
            + EGF+CP C+K   S   LQ H+++ H +      D  G L  + +  K  +  L  +DG             + E    +     S+   +     PQ +G   +    F + R  ++    +E + LI+++EKL SF + N  + + +  E+S+V WV D  VP CP CG KF I +                                               ++HHCRLCG ++C  C+ +++   ASKL +A         S  +   S     +  S +SL S+ S ++ +    IRCC +CK  +  +  QL+ +    EIV  Y++L     KV +  PEY  M QS+  GET Y+    N LR E+ ++ + IDA+  K  +       +   +   L K +  +  LF+Q     L  LP ++  EE+  +R  E ++K    ++       NR  E         + K ++ +     GW PT          GH  NR  ++P                  L  Q+EN+  YI  A  A +V EV+ML++N+  L+ EYD
Sbjct:   10 VREGFLCPLCLKDLQSFYQLQSHYEEEHSED----RDVKGQLKSLVQIAKKAKNKLLKRDG-----------GERAEGGSQERYEAYSYGGVDPCMWDPQEIGAMRSHLSNFKRHRAARIDHYVVEVNKLIIRLEKLTSFDRVNTESVKIRAIEKSVVSWVSDQDVPFCPDCGNKFTIRN-----------------------------------------------RRHHCRLCGSIMCKRCTELITLPFASKLTSASKHSLSAHGSPNLSPSSSAQTSRRGSISSLSSVSSVLEEKDDDKIRCCHHCKDTLLKREQQLDEKEHTPEIVKYYQKLRSCMEKVDEKAPEYIKMAQSINAGETTYNLDHTNNLRVELQKYYELIDALSKKILTLGMNEEPKPHPKTQQLQKMVRYSATLFVQEKLLGLMSLPTKEIYEELKQKRRQENEQKLQRERQAQQCLIWNRRQEGLSILTQAPLTKVVIHAIRKVEGWLPT---------SGHPRNREMSDP------------------LLQQIENITSYIRQAKDAGRVDEVQMLEDNLRQLQEEYD 493
[Close]
BLAST of Rabenosyn-5 vs. Ensembl Xenopus
Match: RBSN (rabenosyn, RAB effector [Source:NCBI gene;Acc:100496168])

HSP 1 Score: 145.206 bits (365), Expect = 6.675e-36
Identity = 145/559 (25.94%), Postives = 236/559 (42.22%), Query Frame = 3 
Query:  105 ITEGFICPECMKKCVSLKNLXXXXXXXXXXXXXXPSDQSGFLGIIKKAKKTFEEILDAKDGELIFSNNLSSNTLKNENNDMDDDPFVSHAFYEEPNIKPQPLGITVNRTEEFLKIRRTKLLRSAIETSSLILKIEKLISF-QSNASNRERKNFEQSIVEWVKDDLVPMCPMCGGKFGINSPISTYSDVPAVLSSNIEQQNTRKQSRFKTAFINFMDMEIEGSGLLIRKKHHCRLCGCVICAHCSYILSAGEASKLVNAINSRFELKES--ILEESRKILWKNDSQNSLDSIKSKIKTQTVYSIRCCGNCKSLIEAKWNQLERRVCDSEIVDLYEELMENRNKVSQLIPEYNTMCQSLCLGETEYSYQRANELRSEIVQFCQKIDAIGNKFKS---RTTTNGSEREATLVKSIYRNTFLFLQNNFATLKQLPQEDKLEEIVNQRLIEIKKKAATMQKNRSPEIEKYLVKSNNDDSGWAPTIPS----NCGYHNEGHNRNTNNPFECDSTDSNTEENTRLTALALQMENVRQYIELAHQAKKVQEVKMLQNNMLDLKLEYD 1751
            + EGF+CP C+K   S   LQ H+++ H +      D  G L  + +  K  +  L  +DG             + E    +     S+   +     PQ +G   +    F + R  ++    +E + LI+++EKL SF + N  + + +  E+S+V WV D  VP CP CG KF I +                                               ++HHCRLCG ++C  C+ +++   ASKL +A         S  +   S     +  S +SL S+ S ++ +    IRCC +CK  +  +  QL+ +    EIV  Y++L     KV +  PEY  M QS+  GET Y+    N LR E+ ++ + IDA+  K  +           +   L K +  +  LF+Q     L  LP ++  EE+  +R  E ++K   +Q+      E+ + +     +  A  +P+    N G    G  R             N E +     L  Q+EN+  YI  A  A +V EV+ML++N+  L+ EYD
Sbjct:   10 VREGFLCPLCLKDLQSFYQLQSHYEEEHSEDR----DVKGQLKSLVQIAKKAKNKLLKRDG-----------GERAEGGSQERYEAYSYGGVDPCMWDPQEIGAMRSHLSNFKRHRAARIDHYVVEVNKLIIRLEKLTSFDRVNTESVKIRAIEKSVVSWVSDQDVPFCPDCGNKFTIRN-----------------------------------------------RRHHCRLCGSIMCKRCTELITLPFASKLTSASKHSLSAHGSPNLSPSSSAQTSRRGSISSLSSVSSVLEEKDDDKIRCCHHCKDTLLKREQQLDEKEHTPEIVKYYQKLRSCMEKVDEKAPEYIKMAQSINAGETTYNLDHTNNLRVELQKYYELIDALSKKILTLGMNEEPKPHPKTQQLQKMVRYSATLFVQEKLLGLMSLPTKEIYEELKQKRRQENEQK---LQR------ERQVTRPLGSAATRADKLPNGDVRNGGLSPSGQIRKVEGWLPTSGHPRNREMS---DPLLQQIENITSYIRQAKDAGRVDEVQMLEDNLRQLQEEYD 494
[Close]
BLAST of Rabenosyn-5 vs. Ensembl Mouse
Match: Rbsn (rabenosyn, RAB effector [Source:MGI Symbol;Acc:MGI:1925537])

HSP 1 Score: 144.05 bits (362), Expect = 1.142e-35
Identity = 146/569 (25.66%), Postives = 247/569 (43.41%), Query Frame = 3 
Query:  105 ITEGFICPECMKKCVSLKNLXXXXXXXXXXXXXXPSDQSGFL-GIIKKAKKTFEEILDAKDGELIFSNNLSSNTLKNENNDMDD-DPFVSHAFYEEPNIKPQPLGITVNRTEEFLKIRRTKLLRSAIETSSLILKIEKLISF-QSNASNRERKNFEQSIVEWVKDDLVPMCPMCGGKFGINSPISTYSDVPAVLSSNIEQQNTRKQSRFKTAFINFMDMEIEGSGLLIRKKHHCRLCGCVICAHCSYILSAGEASKLVNAINSRFELKESILEESRKILW-KNDSQNSLDSIKSKIKTQTVYSIRCCGNCKSLIEAKWNQLERRVCDSEIVDLYEELMENRNKVSQLIPEYNTMCQSLCLGETEYSYQRANELRSEIVQFCQKIDAIGNKFKSRTTTNGSEREAT---LVKSIYRNTFLFLQNNFATLKQLPQEDKLEEIVNQRLIEIKKK-----AATMQKNRSPEIEKYLVKSN--NDD----SGWAPTIPSNCGY--HNEGHNRNTNNPFECDSTDSNTEENTRLTALALQMENVRQYIELAHQAKKVQEVKMLQNNMLDLKLEYD 1751
            + EGF+CP C+K   S   LQ H+++ H++      D  G +  +++KA+K   ++L  ++G+    + +   T   E+      DP++          +PQ LG   +   +F K R  ++    +E + LI+++EKL +F ++N    + +  E+S+V WV D  VP CP CG KF I +                                               ++HHCRLCG ++C  C  ++    A KL +A         S  +    +   +  S +S+ S+ S +  +    IRCC +CK  +  +  Q++ +    +IV LYE+L     KV Q  PEY  M  SL  GET Y+ + AN+LR E+ +  + IDA+  K  +               L + I  +  LF+Q     L  LP +++ EE+  +R  ++++K      A ++  R  E  +  + S+  N D     G  P +    G+   +EG  +         S D +         L  Q+ N+  +I  A  A +  EV+ LQ N+  L+ EYD
Sbjct:   10 VREGFLCPLCLKDLQSFYQLQSHYEEEHLEDR----DVKGQIKNLVQKARKAKNKLL-KREGD----DRVEPGTQGYESFSYGGVDPYM---------WEPQELGAMRSHLSDFKKHRAARIDHYVVEVNKLIIRLEKLTAFDRTNTETSKIRAIEKSVVPWVNDQDVPFCPDCGNKFSIRN-----------------------------------------------RRHHCRLCGSIMCKKCMELIGLPLAHKLTSASKDSLSTHTSPSQSPNSVHGSRRGSISSMSSVSSVLDEKDDDRIRCCTHCKDKLLKREQQMDEKEHTPDIVKLYEKLRLCMEKVDQKAPEYIRMAASLNAGETTYNLEHANDLRVEVQKVYELIDALSKKILTLGLNQDPSPHPNTLRLQRMIRYSATLFVQEKLLGLMSLPTKEQFEELKKKRKQDLEQKRTVERQAALESRRKLEERQSGLASHTANGDVRSLRGIPPPLRKAEGWLPLSEGQGQ---------SEDPD--------PLLQQIYNITSFIRQAKAAGRTDEVRTLQENLRQLQDEYD 496
[Close]
BLAST of Rabenosyn-5 vs. Ensembl Mouse
Match: Rbsn (rabenosyn, RAB effector [Source:MGI Symbol;Acc:MGI:1925537])

HSP 1 Score: 58.9214 bits (141), Expect = 6.337e-10
Identity = 42/128 (32.81%), Postives = 66/128 (51.56%), Query Frame = 3 
Query: 1074 SEIVDLYEELMENRNKVSQLIPEYNTMCQSLCLGETEYSYQRANELRSEIVQFCQKIDAIGNKFKSRTTTNGSEREAT-------LVKSIYRNTFLFLQNNFATLKQLPQEDKLEEIVNQRLIEIKKK 1436
             +IV LYE+L     KV Q  PEY  M  SL  GET Y+ + AN+LR E+ +  + IDA+  K      T G  ++ +       L + I  +  LF+Q     L  LP +++ EE+  +R  ++++K
Sbjct:    4 PDIVKLYEKLRLCMEKVDQKAPEYIRMAASLNAGETTYNLEHANDLRVEVQKVYELIDALSKKI----LTLGLNQDPSPHPNTLRLQRMIRYSATLFVQEKLLGLMSLPTKEQFEELKKKRKQDLEQK 127
[Close]
BLAST of Rabenosyn-5 vs. UniProt/SwissProt
Match: sp|Q80Y56|RBNS5_MOUSE (Rabenosyn-5 OS=Mus musculus OX=10090 GN=Rbsn PE=1 SV=1)

HSP 1 Score: 144.05 bits (362), Expect = 7.989e-35
Identity = 146/569 (25.66%), Postives = 247/569 (43.41%), Query Frame = 3 
Query:  105 ITEGFICPECMKKCVSLKNLXXXXXXXXXXXXXXPSDQSGFL-GIIKKAKKTFEEILDAKDGELIFSNNLSSNTLKNENNDMDD-DPFVSHAFYEEPNIKPQPLGITVNRTEEFLKIRRTKLLRSAIETSSLILKIEKLISF-QSNASNRERKNFEQSIVEWVKDDLVPMCPMCGGKFGINSPISTYSDVPAVLSSNIEQQNTRKQSRFKTAFINFMDMEIEGSGLLIRKKHHCRLCGCVICAHCSYILSAGEASKLVNAINSRFELKESILEESRKILW-KNDSQNSLDSIKSKIKTQTVYSIRCCGNCKSLIEAKWNQLERRVCDSEIVDLYEELMENRNKVSQLIPEYNTMCQSLCLGETEYSYQRANELRSEIVQFCQKIDAIGNKFKSRTTTNGSEREAT---LVKSIYRNTFLFLQNNFATLKQLPQEDKLEEIVNQRLIEIKKK-----AATMQKNRSPEIEKYLVKSN--NDD----SGWAPTIPSNCGY--HNEGHNRNTNNPFECDSTDSNTEENTRLTALALQMENVRQYIELAHQAKKVQEVKMLQNNMLDLKLEYD 1751
            + EGF+CP C+K   S   LQ H+++ H++      D  G +  +++KA+K   ++L  ++G+    + +   T   E+      DP++          +PQ LG   +   +F K R  ++    +E + LI+++EKL +F ++N    + +  E+S+V WV D  VP CP CG KF I +                                               ++HHCRLCG ++C  C  ++    A KL +A         S  +    +   +  S +S+ S+ S +  +    IRCC +CK  +  +  Q++ +    +IV LYE+L     KV Q  PEY  M  SL  GET Y+ + AN+LR E+ +  + IDA+  K  +               L + I  +  LF+Q     L  LP +++ EE+  +R  ++++K      A ++  R  E  +  + S+  N D     G  P +    G+   +EG  +         S D +         L  Q+ N+  +I  A  A +  EV+ LQ N+  L+ EYD
Sbjct:   10 VREGFLCPLCLKDLQSFYQLQSHYEEEHLEDR----DVKGQIKNLVQKARKAKNKLL-KREGD----DRVEPGTQGYESFSYGGVDPYM---------WEPQELGAMRSHLSDFKKHRAARIDHYVVEVNKLIIRLEKLTAFDRTNTETSKIRAIEKSVVPWVNDQDVPFCPDCGNKFSIRN-----------------------------------------------RRHHCRLCGSIMCKKCMELIGLPLAHKLTSASKDSLSTHTSPSQSPNSVHGSRRGSISSMSSVSSVLDEKDDDRIRCCTHCKDKLLKREQQMDEKEHTPDIVKLYEKLRLCMEKVDQKAPEYIRMAASLNAGETTYNLEHANDLRVEVQKVYELIDALSKKILTLGLNQDPSPHPNTLRLQRMIRYSATLFVQEKLLGLMSLPTKEQFEELKKKRKQDLEQKRTVERQAALESRRKLEERQSGLASHTANGDVRSLRGIPPPLRKAEGWLPLSEGQGQ---------SEDPD--------PLLQQIYNITSFIRQAKAAGRTDEVRTLQENLRQLQDEYD 496
[Close]
BLAST of Rabenosyn-5 vs. UniProt/SwissProt
Match: sp|Q9H1K0|RBNS5_HUMAN (Rabenosyn-5 OS=Homo sapiens OX=9606 GN=RBSN PE=1 SV=2)

HSP 1 Score: 140.969 bits (354), Expect = 7.594e-34
Identity = 145/567 (25.57%), Postives = 244/567 (43.03%), Query Frame = 3 
Query:  105 ITEGFICPECMKKCVSLKNLXXXXXXXXXXXXXXPSDQSGFLGIIKKAKKTFEEILDAKDGELIFSNNLSSNTLKNENNDMDD-DPFVSHAFYEEPNIKPQPLGITVNRTEEFLKIRRTKLLRSAIETSSLILKIEKLISF-QSNASNRERKNFEQSIVEWVKDDLVPMCPMCGGKFGINSPISTYSDVPAVLSSNIEQQNTRKQSRFKTAFINFMDMEIEGSGLLIRKKHHCRLCGCVICAHCSYILSAGEASKLVNAINSRFELKESILEESRKILW-KNDSQNSLDSIKSKIKTQTVYSIRCCGNCKSLIEAKWNQLERRVCDSEIVDLYEELMENRNKVSQLIPEYNTMCQSLCLGETEYSYQRANELRSEIVQFCQKIDAIGNKFKSRTTTNGSEREAT---LVKSIYRNTFLFLQNNFATLKQLPQEDKLEEIVNQRLIE------IKKKAATMQKNRSPEIEKYLV-KSNNDD-----SGWAPTIPSNCGYHNEGHNRNTNNPFECDSTDSNTEENTRLTALALQMENVRQYIELAHQAKKVQEVKMLQNNMLDLKLEYD 1751
            + EGF+CP C+K   S   L  H+++ H  +      Q     +++KAKK  + +L  ++G+    +   S T   E+      DP++          +PQ LG   +   +F K R  ++    +E + LI+++EKL +F ++N  + + +  E+S+V WV D  VP CP CG KF I +                                               ++HHCRLCG ++C  C  ++S   A+KL +A         S  +    +   +  S +S+ S+ S +  +    IRCC +CK  +  +  Q++ +    +IV LYE+L     KV Q  PEY  M  SL  GET YS + A++LR E+ +  + IDA+  K  +           +   L + I  +  LF+Q     L  LP +++ EE+  +R  E      ++++AA   + R  E +  L  ++ N +      G AP              R              +E++     L  Q+ N+  +I  A  A ++ EV+ LQ N+  L+ EYD
Sbjct:   10 VREGFLCPLCLKDLQSFYQLHSHYEEEHSGEDRDVKGQ--IKSLVQKAKKAKDRLL-KREGD----DRAESGTQGYESFSYGGVDPYM---------WEPQELGAVRSHLSDFKKHRAARIDHYVVEVNKLIIRLEKLTAFDRTNTESAKIRAIEKSVVPWVNDQDVPFCPDCGNKFSIRN-----------------------------------------------RRHHCRLCGSIMCKKCMELISLPLANKLTSASKESLSTHTSPSQSPNSVHGSRRGSISSMSSVSSVLDEKDDDRIRCCTHCKDTLLKREQQIDEKEHTPDIVKLYEKLRLCMEKVDQKAPEYIRMAASLNAGETTYSLEHASDLRVEVQKVYELIDALSKKILTLGLNQDPPPHPSNLRLQRMIRYSATLFVQEKLLGLMSLPTKEQFEELKKKRKEEMERKRAVERQAALESQRRLEERQSGLASRAANGEVASLRRGPAPL-------------RKAEGWLPLSGGQGQSEDS---DPLLQQIHNITSFIRQAKAAGRMDEVRTLQENLRQLQDEYD 497
[Close]
BLAST of Rabenosyn-5 vs. TrEMBL
Match: A0A0L8I5T7 (Uncharacterized protein OS=Octopus bimaculoides OX=37653 GN=OCBIM_22033398mg PE=4 SV=1)

HSP 1 Score: 188.348 bits (477), Expect = 3.456e-49
Identity = 163/569 (28.65%), Postives = 264/569 (46.40%), Query Frame = 3 
Query:  105 ITEGFICPECMKKCVSLKNLXXXXXXXXXXXXXXPSDQSGFLGIIKKAKK-TFEEILDAKDGELIFSNNLSSNTLKNENNDMDDDPFVSHAFYEEPNIKPQPLGITVNRTEEFLKIRRTKLLRSAIETSSLILKIEKLISFQSNASNRERKNFEQSIVEWVKDDLVPMCPMCGGKFGINSPISTYSDVPAVLSSNIEQQNTRKQSRFKTAFINFMDMEIEGSGLLIRKKHHCRLCGCVICAHCSYILSAGEASKLVN-AINSRFELKESILEESRKILWKNDSQNSLDSIKSKIKTQTVYSIRCCGNCKSLIEAKWNQLERRVCDSEIVDLYEELMENRNKVSQLIPEYNTMCQSLCLGETEYSYQRANELRSEIVQFCQKIDAIGNKFKSRTTTNGSE---REATLVKSIYRNTFLFLQNNFATLKQLPQEDKLEEIVNQRLIEIKKKAATMQKNRSPEIEKYLVKSNNDDSGWAPTIPSNCGYHNEGH-------NRNTNN--------PFECDSTDSNTEENTRLTALALQMENVRQYIELAHQAKKVQEVKMLQNNMLDLKLEYD 1751
            I EGFICP C+K   S+  LQ HF+  H  + +  S Q    G+ +KAKK    ++L  K+         S+N L          P +   F+E     PQ +GI+ + TE F  IR  ++ R  IET+ L+++++KLIS ++     +RK FE+++V WV D  VPMCP C   F                                               ++ R++HHCRLCG ++C  CS+ +S   A KL + A N          ++    L ++ S  SL+S+ S    Q    IR C +C+ L+E + + +E+R     IV LYE+L     +  Q +P +  M +SL  GE+ YS   AN+LR ++++  + ID I  K  +    N +    R+  L ++I   +  FL+ N + ++QLP +++ E++ N   +E+++K A  +K      E  L +          +  S+   H + H       +R   N        P E  S   NT +      +  Q+E +  YI+ A QA+K  EV+ML+ N+ +L+LEY+
Sbjct:    6 IREGFICPICLKDYSSVTQLQTHFEDAHTTEEKAVSQQ--LKGLFEKAKKRLLGDMLGEKEDSFDDREQSSTNALI---------PGLYPFFWE-----PQEIGISRSHTETFKAIRDARVDRFVIETNKLLIRLDKLISPEAPTDPNKRKVFEKTVVPWVNDADVPMCPSCARTF-----------------------------------------------IVTRRRHHCRLCGGIVCDRCSHFMSFSFAKKLTDPAFN---------FQKESGFLKRSGSDTSLNSMFSAEGEQ---HIRTCLDCRRLLERRDSLVEQRNLKPVIVQLYEKLRTCIEEAEQQLPRFLPMVESLSNGESTYSLNEANQLRCQLLKLYEYIDIISKKILTLGVNNETSPPLRQLYLQRAIRTFSSNFLKENLSGIQQLPSQEEYEKMKNSHTVEMQQKFALERK------EAMLAQEQEQQKSSTDSSTSSFSQHRQHHSPSQEDASRTETNGNIGKGWKPSEISSYSQNTND-----PMLQQIEIICGYIKQAKQAQKFDEVEMLEQNLQELQLEYN 488
[Close]
BLAST of Rabenosyn-5 vs. TrEMBL
Match: A0A0R3VVR0 (C2H2-type domain-containing protein OS=Taenia asiatica OX=60517 GN=TASK_LOCUS1486 PE=4 SV=1)

HSP 1 Score: 183.726 bits (465), Expect = 2.168e-47
Identity = 142/484 (29.34%), Postives = 230/484 (47.52%), Query Frame = 3 
Query:  393 IKPQPLGITVNRTEEFLKIRRTKLLRSAIETSSLILKIEKLISFQSNASNRERKNFEQSIVEWVKDDLVPMCPMCGGKFGI-----NSPISTYSDV--------PAVLSSNIEQQNTRKQSRFKTAFINFMDMEIEGSGLLIRKKHHCRLCGCVICAHCSYILSAGEASKLVNAIN---------------SRFELKESILEESRKILWKNDSQNSLDSIKSKIKTQTVYSIRCCGNCKSLIEAKWNQLERRVCDSEIVDLYEELMENRNKVSQLIPEYNTMCQSLCLGETEYSYQRANELRSEIVQFCQKIDAIGNKFKSR--TTTNGSEREATLVKSIYRNTFLFLQNNFATLKQLPQEDKLEEIVNQRLIEI--KKKAATMQKNRSPEIEKYLVKSNNDDSGWAPTIPSNCGYHNEGHNRNTNNPFECDSTDSNTEENTRLTALALQMENVRQYIELAHQA-KKVQEVKMLQNNMLDLKLE 1745
            +K   +G   +RT +F K+R+ ++ R+A+ET+ L++++EKL +   N  N +R   EQSIV W+K   V +CP CG  FG      ++P S+ S V        PA   S   +++    SRF    I+        S  + R+ HHCRLCG +ICA CS+ LS  E S ++ A N               +    K  IL+    +L ++ S  SLDS   K + + V  +R C  CKS++E K  Q+E        ++ ++ L     KV++ +P +++M  SL  GE +Y  + A  LR E++Q  +K+D IG    S   +T+  +  +A L ++I +    F+QNN  +L+ LP E +   +  +R  E+  K++  TM                + D+GW P+  S+  Y  E            D +D           L  QM+ V  Y+  A  A + V+E+  L  N+ +L+ E
Sbjct:   54 VKAPVIGKIRSRTSDFDKLRQAQVDRTALETNLLLIRLEKLSNIPDNLDNSKRHVLEQSIVPWIKAK-VSLCPRCGASFGFGWSKDSTPDSSPSLVTSQRFPVSPAASLSRQARESLHLASRFVATLID--------SDPVYRRVHHCRLCGHIICADCSFFLSKEEVSHVMKACNWAGGGSLRSGIVSSENILPYKGGILKHKPPLLLRSTSATSLDSAVPK-RMEEVPKLRICEVCKSVLEGKLQQIEESNATPLGLEEFQALKRAMAKVTEKMPLFSSMASSLNSGEEKYILEIAKSLRLELLQSLRKVDEIGKAIASLDVSTSRSAATQARLNRTIGQFARRFVQNNLPSLRVLPSEMEHRRLAQKRTTELESKRQEVTM----------------SSDAGWMPSSVSSGEYFVEVSTTAKEEAVGFDESDPR-------VVLMRQMDLVADYLMQAQAAHRSVEEITNLAQNLAELESE 504
[Close]
BLAST of Rabenosyn-5 vs. TrEMBL
Match: V4A1G3 (Uncharacterized protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_217928 PE=4 SV=1)

HSP 1 Score: 180.644 bits (457), Expect = 3.016e-46
Identity = 155/567 (27.34%), Postives = 255/567 (44.97%), Query Frame = 3 
Query:  105 ITEGFICPECMKKCVSLKNLXXXXXXXXXXXXXXPSDQSGFL---GIIKKAKKTFEEILDAKDGELIFSNNLSSNTLKNENNDMDDDPFVSHAFYEEPNIKPQPLGITVNRTEEFLKIRRTKLLRSAIETSSLILKIEKLISFQSNASNRERKNFEQSIVEWVKDDLVPMCPMCGGKFGINSPISTYSDVPAVLSSNIEQQNTRKQSRFKTAFINFMDMEIEGSGLLIRKKHHCRLCGCVICAHCSYILSAGEASKLVNAINSRFEL---KESILEESRKILWKNDSQNSLDSIKSKIKTQTVYSIRCCGNCKSLIEAKWNQLERRVCDSEIVDLYEELMENRNKVSQLIPEYNTMCQSLCLGETEYSYQRANELRSEIVQFCQKIDAIGNKFKS---RTTTNGSEREATLVKSIYRNTFLFLQNNFATLKQLPQEDKLEEIVNQRLIEIKKKAATMQKNRSPEIEKYLVKSNNDDSGWAPTIPSNCGYHNEGHNRNTNNPFECDSTDS------NTEENTRLTALA----LQMENVRQYIELAHQAKKVQEVKMLQNNMLDLKLEY 1748
            I EGF+CP CMK   ++  LQ+HF+  H        D++ F    G   KAKK    IL  ++ E              EN+  D  P ++ + ++    + Q LG   N T+ F  +R  ++    +ET+ L+++++KL+  ++     +RK FE+S+V WV D  VP C  C   F I                                               +R+KHHCRLCG ++C  CS  L+   A K          L        E     L ++DS  SL+S+   +  +    +R C  C+ L+E +   +E+R      V LYE++ E  +  + LIP+Y  M  SL +GE  YS + A  LR+++++    +D I  K ++   +  +  + ++  L K+I  +   F+Q N   L+ LP  ++ +E+  +R  E+++K A     R   +E    +  N +    P    + G    GH RN       DS DS       TEE ++++ +      QME +R YI+ A +AK+  E++ML++N+ DLK EY
Sbjct:    7 IMEGFLCPMCMKDFGTVSQLQEHFEVAHSS-----EDKAVFQSLKGFFDKAKK---RILGDRENEF------------GENSSSDSSPNLNLSGFDPTWWEFQELGCVRNHTDAFKAVRDARIDHFVVETNKLLIRLDKLLDPEAPKEASKRKGFEKSVVPWVPDGAVPCCLSCEESFNI-----------------------------------------------MRRKHHCRLCGGIMCNKCSEFLTLTYARKFFVFTEYFLALIVNPAVTFEGESGFLKRSDSSTSLNSL---MGLEAEGHMRVCKTCRKLLERRDQMVEQRNIKPNFVVLYEKMQECMSNANDLIPQYLPMVDSLSMGEATYSLKEAELLRTKLIRLYDAVDQISKKIQNLEIKPDSPSAFKQQQLQKAIRMSASGFMQENLMGLQALPTSEQYQELQAKRRAEVQRKIAA---ERQAAMEAQNRERFNQEESEKPGKILSIG-KKLGHVRN-------DSQDSVGRGWKPTEEGSKVSKVGDPMLQQMEIIRGYIKQAREAKRWDEMEMLEHNLKDLKDEY 492
[Close]
BLAST of Rabenosyn-5 vs. TrEMBL
Match: A0A4V3SDB5 (C2H2-type domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_008804 PE=4 SV=1)

HSP 1 Score: 181.03 bits (458), Expect = 4.704e-46
Identity = 144/523 (27.53%), Postives = 244/523 (46.65%), Query Frame = 3 
Query:  102 SITEGFICPECMKKCVSLKNLXXXXXXXXXXXXXXPSDQSGFLGIIKKAKKTFEEILDAKDGELIFSNNLSSNTLKNENNDMDDDPFVSHAFYEEPNIKPQPLGITVNRTEEFLKIRRTKLLRSAIETSSLILKIEKLISFQSNASNRERKNFEQSIVEWVKDDLVPMCPMCGGKFGIN----SPISTYSDVP--AVLSSNIEQQNTRKQSRFKTAFINFMDMEIEGSGLLIRKKHHCRLCGCVICAHCSYILSAGEASKLVNAINSRFELKESILEESRKILWKNDSQNS-------LDSIKSKI----------------KTQTVYS-IRCCGNCKSLIEAKWNQLERRVCDSEIVDLYEELMENRNKVSQLIPEYNTMCQSLCLGETEYSYQRANELRSEIVQFCQKIDAIGNKFKSRTTTNGSERE--------------AT--LVKSIYRNTFLFLQNNFATLKQLPQEDKLEEIVNQRLIEIKKKAATMQKNRSPEIEKYLVKSNNDDSGWAPTIPS 1532
            SI EGFICP CM    + + L+ HF+  H       S  +G              +LD +   +  S+N+                 +S AFYE+   + QPLG + + T EF K+RR+++ R A+ET+SL++++EKLI+     S  +R+ FEQS++ W+    V +CP CG  FG+      P+   S  P  +   S I    T  Q R  T  I  +   I     + R++HHCRLCG V+CA CS  L    A +L+  + +    +  + E + K+  +  SQ +       + S+ SK+                +T + +  +R C  CK L++ K ++L+ R C S +  L+ EL E+  KV++ +P Y+ + +SL  GE  Y+   A  +R E+++  Q+ID I  +     +T   +R+              AT  L++++ +    FLQ N   L+ LP   +   +  QR  E+  + A  ++  + ++E  + K+    +  A   P+
Sbjct:    6 SIIEGFICPGCMVSFRTAEVLRVHFEAEHKSDTTACSRSTG-------------GVLDQRRHSVALSDNIP----------------ISLAFYEQTRFEKQPLGQSKSLTSEFHKLRRSRVNRDALETNSLLIRLEKLIN-APPMSKIQRREFEQSVISWIDATKVDLCPSCGKTFGLGLEEAYPVDESSHNPPQSASQSGINPMTTVAQRRKLT--ITRITSAILDYNPIYRRRHHCRLCGHVLCADCSCFLPRISAVRLLETVGTH---QLGVSEFTSKVGSEPSSQTTESSNLTPVSSLDSKVIFLSSTDYPVPVLDIERTDSTFQCLRLCAVCKDLLQKKLDRLQFRQCASPVTSLHSELREHMRKVNESLPLYSAVAESLHSGEQRYALDMAKSMRHELLESLQQIDFIRRRLDEMASTMAPDRDPRSPNDAADRPANLATIRLLRTLSKMACQFLQTNLPPLRALPTLQQYGSLTAQRQDELAARWAEEEQALA-QLELRIAKATKSSAPLASDGPT 492
[Close]
BLAST of Rabenosyn-5 vs. TrEMBL
Match: C3YPL0 (Uncharacterized protein OS=Branchiostoma floridae OX=7739 GN=BRAFLDRAFT_215186 PE=4 SV=1)

HSP 1 Score: 179.874 bits (455), Expect = 7.630e-46
Identity = 151/590 (25.59%), Postives = 265/590 (44.92%), Query Frame = 3 
Query:  105 ITEGFICPECMKKCVSLKNLXXXXXXXXXXXXXXPSDQSGFLGIIKKAKKTFEEILDAKDGELIFSNNLSSNTLKNENNDMDDDPFVSHAFYE---EPNI-KPQPLGITVNRTEEFLKIRRTKLLRSAIETSSLILKIEKLISF-QSNASNRERKNFEQSIVEWVKDDLVPMCPMCGGKFGINSPISTYSDVPAVLSSNIEQQNTRKQSRFKTAFINFMDMEIEGSGLLIRKKHHCRLCGCVICAHCSYILSAGEASKLVNAINSRFELKESILEESRKILWKNDSQNSLDSIKSKIKTQTVY-----SIRCCGNCKSLIEAKWNQLERRVCDSEIVDLYEELMENRNKVSQLIPEYNTMCQSLCLGETEYSYQRANELRSEIVQFCQKIDAIGNKFKSRTTTNGSEREAT-----LVKSIYRNTFLFLQNNFATLKQLPQEDKLEEIVNQRLIEIKKKAA----------------------TMQKNRSPEIEKYLVKSNNDDS-----GWAPTIPSNCGYHNEGHNRNTNNPFECDSTDSNTEENTRLTALALQMENVRQYIELAHQAKKVQEVKMLQNNMLDLKLEY 1748
            I EGF+CP CMK   +++ LQ+HF++ H  + +    Q    G+  +AK   +  + A       S + SSN +            +S A+Y    +P + +PQ  G + +  + F KIR  ++    IE + L++++EKLI+F ++N    ++K FE  +V W  DD VP CP CG KF ++                                               R++HHCRLCG ++C  CS  L+    +KLVN   +   ++    EE       +    +++S++S +             R C +C +++  +  Q++ +     IV LYE+L    +KV  + PEY  M +SL  GET Y+ + AN +RS++++  + ID IG K  +    +G+E++ +     L + I ++  LF+Q+N   L  LP ED+L ++  QR +EI+++ A                      + +K+R       +  +N D +     GW P +                        DS++   T    +  QM+ +R +++ A  A ++ EV+ML+ N+ +L+ EY
Sbjct:   10 IREGFLCPICMKDLQTVQQLQNHFEEAHNTEADKQVFQH-LKGLFGRAKIRVDRGMAA-------SRSDSSNQVA----------VLSTAYYVGGVDPTMWEPQDFGTSRSHMDSFKKIRDARIDFYVIEMNKLLIRLEKLIAFDRTNPDPVKKKEFEIGLVPWAPDDAVPYCPTCGEKFNLS-----------------------------------------------RRRHHCRLCGGIMCNRCSQFLTPDFTAKLVNKAGN-LPVQTIRGEEKGHRRQGSAGTRAMESLRSLVGEVVGEEPREDGTRTCQDCMAVMGRRERQIQEKTTKPIIVQLYEKLRMLMDKVEAMCPEYIKMAESLNAGETSYNLEHANNVRSQLMRCYEAIDTIGKKIAT-MGASGAEQQLSPQAIRLQQGIRKHCTLFIQDNVFGLPSLPSEDQLRKLQEQRRLEIEQRLALERQAALEAEERRRSEEQRKRSSPEKDRKGAAAATVDTTNRDRTESIGKGWTPAV------------------------DSSSVATTETDPMLQQMDIIRSFVDQARAAGRLDEVEMLEANLRELQQEY 508
[Close]
BLAST of Rabenosyn-5 vs. Ensembl Cavefish
Match: rbsn (rabenosyn, RAB effector [Source:NCBI gene;Acc:103046128])

HSP 1 Score: 139.043 bits (349), Expect = 3.587e-34
Identity = 146/564 (25.89%), Postives = 237/564 (42.02%), Query Frame = 3 
Query:  105 ITEGFICPECMKKCVSLKNLXXXXXXXXXXXXXXPSDQSGFLGIIK---KAKKTFEEILDAKDGELIFSNNLSSNTLKNENNDMDDDPFVSHAFYEEPNIKPQPLGITVNRTEEFLKIRRTKLLRSAIETSSLILKIEKLISF-QSNASNRERKNFEQSIVEWVKDDLVPMCPMCGGKFGINSPISTYSDVPAVLSSNIEQQNTRKQSRFKTAFINFMDMEIEGSGLLIRKKHHCRLCGCVICAHCSYILSAGEASKLVNAINSRFELKESILEESRKILWKNDSQNSLDSIKSKIKTQTVYSIRCCGNCKSLIEAKWNQLERRVCDSEIVDLYEELMENRNKVSQLIPEYNTMCQSLCLGETEYSYQRANELRSEIVQFCQKIDAIGNKFKS---RTTTNGSEREATLVKSIYRNTFLFLQNNFATLKQLPQEDKLEEIVNQRLIEIKKK------AATMQKNRSPEIEKYLVKSNNDDSGWAPTIPSNCGYHNEGHNRNTNNPFECDSTDSNTEENTRL-TALALQMENVRQYIELAHQAKKVQEVKMLQNNMLDLKLEYDA 1754
            + EGF+CP C+K   S   LQDH+++ H        D     G IK   +  K  ++ L  +DG+     +  S            DP++          +PQ LG T +  + F K R  ++    IE +  I+++EKL SF ++N    + +  E+S+V WV D  VP CP CGGKF I +                                               ++HHCRLCG ++C  C   +    A KL                  ++ L +  S +SL S+ S ++ +    IRCC +C   +    ++LE +    +IV LYE L    +KV +  PEY  M +SL  GE  Y+ + A  LR E+ ++ + IDA+  K  +   +      +R   L + +  +  LF+Q     L  LP ++K  E+  +R +E +K+      AA   + R  EI+K     N +     P           G  R T        +D+    +  L   L  Q++N+  +++ A  A +  E+ ML+ N+  L+ E+DA
Sbjct:    7 VKEGFLCPLCLKDLQSFYQLQDHYEEEHS------GDSHHVGGQIKSLVQKAKKAKDKLLKRDGDERTETSYESFYCGGV------DPYM---------WEPQELGATRSHLDLFKKHRAARIDHYVIEVNKRIIRLEKLTSFDRTNMDAGKIRALEKSVVPWVSDHDVPFCPDCGGKFNIRN-----------------------------------------------RRHHCRLCGSIMCRKCMEFVPLPLACKL---------------HSPQQQLPRRGSISSLSSVSSVLEEKDEDRIRCCRHCMEALLRHQHKLEEKDHVPDIVKLYERLRICMDKVDEKAPEYIRMAESLHAGEITYNLETAGVLRMEVQKYYEHIDALSKKILTLGMKDDVQPHQRTLQLQRMVRYSATLFVQEKLLGLMSLPTKEKYLELKEKRKVEQEKRIQQERLAALESQKRHSEIDKNRTTLNANGDALRPA----------GGPRMTKAGGWLPLSDTAHSRSRELDDPLLQQIDNIESFLKQARAANRTDEIAMLEENLRQLQDEFDA 477
[Close]
BLAST of Rabenosyn-5 vs. Ensembl Cavefish
Match: rbsn (rabenosyn, RAB effector [Source:NCBI gene;Acc:103046128])

HSP 1 Score: 138.658 bits (348), Expect = 5.408e-34
Identity = 123/474 (25.95%), Postives = 204/474 (43.04%), Query Frame = 3 
Query:  396 KPQPLGITVNRTEEFLKIRRTKLLRSAIETSSLILKIEKLISF-QSNASNRERKNFEQSIVEWVKDDLVPMCPMCGGKFGINSPISTYSDVPAVLSSNIEQQNTRKQSRFKTAFINFMDMEIEGSGLLIRKKHHCRLCGCVICAHCSYILSAGEASKLVNAINSRFELKESILE----------ESRKILWKNDSQNSLDSIKSKIKTQTVYSIRCCGNCKSLIEAKWNQLERRVCDSEIVDLYEELMENRNKVSQLIPEYNTMCQSLCLGETEYSYQRANELRSEIVQFCQKIDAIGNKFKS---RTTTNGSEREATLVKSIYRNTFLFLQNNFATLKQLPQEDKLEEIVNQRLIEIKKK------AATMQKNRSPEIEKYLVKSNNDDSGWAPTIPSNCGYHNEGHNRNTNNPFECDSTDSNTEENTRL-TALALQMENVRQYIELAHQAKKVQEVKMLQNNMLDLKLEYDA 1754
            +PQ LG T +  + F K R  ++    IE +  I+++EKL SF ++N    + +  E+S+V WV D  VP CP CGGKF I +                                               ++HHCRLCG ++C  C   +    A KL ++      +  S  +            ++ L +  S +SL S+ S ++ +    IRCC +C   +    ++LE +    +IV LYE L    +KV +  PEY  M +SL  GE  Y+ + A  LR E+ ++ + IDA+  K  +   +      +R   L + +  +  LF+Q     L  LP ++K  E+  +R +E +K+      AA   + R  EI+K     N +     P           G  R T        +D+    +  L   L  Q++N+  +++ A  A +  E+ ML+ N+  L+ E+DA
Sbjct:   94 EPQELGATRSHLDLFKKHRAARIDHYVIEVNKRIIRLEKLTSFDRTNMDAGKIRALEKSVVPWVSDHDVPFCPDCGGKFNIRN-----------------------------------------------RRHHCRLCGSIMCRKCMEFVPLPLACKLTSSTREALFVPGSPGKGGSPSAGGPAAPQQQLPRRGSISSLSSVSSVLEEKDEDRIRCCRHCMEALLRHQHKLEEKDHVPDIVKLYERLRICMDKVDEKAPEYIRMAESLHAGEITYNLETAGVLRMEVQKYYEHIDALSKKILTLGMKDDVQPHQRTLQLQRMVRYSATLFVQEKLLGLMSLPTKEKYLELKEKRKVEQEKRIQQERLAALESQKRHSEIDKNRTTLNANGDALRPA----------GGPRMTKAGGWLPLSDTAHSRSRELDDPLLQQIDNIESFLKQARAANRTDEIAMLEENLRQLQDEFDA 510
[Close]
BLAST of Rabenosyn-5 vs. Ensembl Sea Lamprey
Match: rbsn (rabenosyn, RAB effector [Source:ZFIN;Acc:ZDB-GENE-100525-1])

HSP 1 Score: 125.176 bits (313), Expect = 1.881e-30
Identity = 108/450 (24.00%), Postives = 185/450 (41.11%), Query Frame = 3 
Query:  498 LKIEKLISFQSNASNRERKN--FEQSIVEWVKDDLVPMCPMCGGKFGINSPISTYSDVPAVLSSNIEQQNTRKQSRFKTAFINFMDMEIEGSGLLIRKKHHCRLCGCVICAHCSYILSAGEASKLVNA-----INSRFELKESILEESRKILWKNDSQNSLDSIKSKIKTQTVYSIRCCGNCKSLIEAKWNQLERRVCDSEIVDLYEELMENRNKVSQLIPEYNTMCQSLCLGETEYSYQRANELRSEIVQFCQKIDAIGNKFKSRTTTNGSEREA---TLVKSIYRNTFLFLQNNFATLKQLPQEDKLEEIVNQRLIEIKKKAATMQKNRSPEIEKYLVKSN--------------NDDSGWAP--TIPSNCGYHNEGHNRNTNNPFECDSTDSNTEENTRLTALALQMENVRQYIELAHQAKKVQEVKMLQNNMLDLKLEYDALRKKL 1769
            L + +L SF    ++  ++    E+ +V WV D+ VP CP CG  F + S                                               ++HHCRLCG ++C  C++ L+   A    +A        ++     +  E R+      S +S+ S+   ++ +    +RCC +C+  +    +Q++ +     IV LYE+L ++  KV QL PEY  M  SL  GET Y+  + N +R E+++  + +D I  K  +    +     A    L K I  +  LF+Q     L+ LP  D+ EE+   R  E + +   MQ+ ++  ++    +                +  +GW P   +P++     EGH        E D              L  Q+ N+R Y+  A  A +V E + L+ N+  L+ EYDA + +L
Sbjct:    1 LSLNQLTSFDRVNTDPAKRAAALERLVVTWVSDEDVPCCPDCGRGFSVTS-----------------------------------------------RRHHCRLCGSIMCKRCTHFLTVAFAGASHSAGCKALATHKYASFPPLSIEHRR----RGSTSSVGSLL--LEDKDDERVRCCRHCREALVRHEHQMDEQHHQPAIVALYEKLHQSTVKVEQLAPEYGRMADSLNAGETTYTLDQGNAMRMELMKLYELVDVISKKILNLGVKDDPPPHAKALKLQKMIRYSVSLFVQEKLLGLQSLPTADRYEELKEGRRREAESR--VMQERQATSLDSQQQQQRQQQQQQPRRQRPAVDSATGWLPESGVPASG---MEGHGGPIG---ELDDP------------LLQQIANIRSYVRQAVAAGRVDEARTLRENLQQLQQEYDAQQMEL 377
[Close]
BLAST of Rabenosyn-5 vs. Ensembl Nematostella
Match: EDO39044 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SB89])

HSP 1 Score: 93.9745 bits (232), Expect = 7.897e-21
Identity = 86/342 (25.15%), Postives = 138/342 (40.35%), Query Frame = 3 
Query:  402 QPLGITVNRTEEFLKIRRTKLLRSAIETSSLILKIEKLISFQSNASNRERKNFEQSIVEWVKDDLVPMCPMCGGKFGINSPISTYSDVPAVLSSNIEQQNTRKQSRFKTAFINFMDMEIEGSGLLIRKKHHCRLCGCVICAHCSYILS---AG-EASKLVNAINSRFELKESI-LEESRKILWKNDSQNSLDSIKSKIKTQTVYSIRCCGNCKSLIEAKWNQLERRVCDSEIVDLYEELMENRNKVSQLIPEYNTMCQSLCLGETEYSYQRANELRSEIVQFCQKIDAIGNKFKSRTTTNGSEREATLVK---SIYRNTFLFLQNNFATLKQLPQEDKLEEI 1403
            Q  G T + T  F + R  ++ R  + T+ +++++EK+ + +       +   E+S+V WV D  V  CP+C   F                                                L R++HHCRLCG +ICA CS  ++   AG EAS     I  R +L +S  L +  K   ++D+                  IR C  CK L      Q   +     IV LYE++ +  +   +L P Y  M  SL +G+ +Y    A  LR ++++  + +D I  K  +  + +     A L K    I      +LQ N  TL  LPQ D+++ +
Sbjct:   91 QEFGATRSYTRLFEERRDAEIDRFVVNTNKILIRLEKVTNQRLWGQPLTK---ERSLVPWVADSEVDFCPICKKSFN-----------------------------------------------LARRRHHCRLCGGIICAKCSISVAVNFAGKEASASREVICERLKLDKSADLPQGSKRRSRDDTDEP--------------GIRACQVCKILYSRYEKQEREKQTTPVIVQLYEKMKQQMSDAEKLHPLYIKMVDSLNIGDVQYELTEAGNLRIKLIKSYEAVDVISKKIGALGSQDEMPPSAQLTKLQRGIRAFASGYLQENMFTLPNLPQHDQVKRL 368
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BLAST of Rabenosyn-5 vs. Ensembl Medaka
Match: rbsn (rabenosyn, RAB effector [Source:NCBI gene;Acc:101169204])

HSP 1 Score: 129.028 bits (323), Expect = 7.158e-31
Identity = 151/579 (26.08%), Postives = 244/579 (42.14%), Query Frame = 3 
Query:  105 ITEGFICPECMKKCVSLKNLXXXXXXXXXXXXXXPSDQSGFLGIIKKAKKTFEEILDAKDGELIFSNNLSSNTLKNENNDMDDDPFVSHAFYEEPNIKPQPLGITVNRTEEFLKIRRTKLLRSAIETSSLILKIEKLISF-QSNASNRERKNFEQSIVEWVKDDLVPMCPMCGGKFGINSPISTYSDVPAVLSSNIEQQNTRKQSRFKTAFINFMDMEIEGSGLLIRKKHHCRLCGCVICAHCSYILSAGEASKLVNAINSRFELKES--------ILEESRKILWKNDSQNSLDSIKSKIKTQTVYSIRCCGNCKSLIEAKWNQLERRVCDSEIVDLYEELMENRNKVSQLIPEYNTMCQSLCLGETEYSYQRANELRSEIVQFCQKIDAIGNKFKS---RTTTNGSEREATLVKSIYRNTFLFLQNNFATLKQLPQEDKLEEIV------NQRLIEIKKKAATMQKNRSPEIEKYLVKSNND------------DSGWAPTIPSNCGYHNEGHNRNTNNPFECDSTDSNTEENTRLTALALQMENVRQYIELAHQAKKVQEVKMLQNNMLDLKLEYD 1751
            + EGF+CP C+K   S   LQ H+++ H           G L  + +  K  ++ L  +DGE    + L + + ++       DP++          +PQ LG T +  + F K R  ++    IE + LI+++EKL SF + N+ + + +  E+S+V WV D  VP CP CG KF I +                                               ++HHCRLCG ++C  C   +    A KL+        +  S            S  +  +  S +SL S+ S ++ +    IRCC +C   +  K  +L+ +    +IV LYE LM    KV +  P+Y  M +SL  GET Y+   A  LR E+ ++ + IDA+  K  +   +       +   L K I  +  LF+Q     L  LP ++K EE+        +R ++ ++ AA     R  E EK    +N +             SGW P+  S        H+R            S  E+      L  Q++N++ ++  A +A+K  EV ML+ N+  L+ EYD
Sbjct:   15 VKEGFLCPLCLKDLQSFYQLQGHYEEEHSGDDRH---VRGQLKSLVQKAKKAKDKLLKRDGE----DRLDTGSYESFYYG-GVDPYM---------WEPQELGATRSHLDIFKKHRAARIDHYVIEVNKLIIRLEKLTSFDRVNSDSAKIRAIEKSVVSWVNDSDVPFCPDCGNKFNIRN-----------------------------------------------RRHHCRLCGSIMCRRCMEFVPLPLAQKLIYGTREALCVPGSPGQTQTLPAGGGSSGMGSRRGSISSLSSVTSMLEEKDDEKIRCCHHCMDTLLKKQQKLDEKDNIPDIVKLYERLMMCMVKVDEKAPDYIRMAESLNAGETTYNLDTAGGLRLEVQKYYELIDALSKKILTLGLKDEPPPHPKALQLQKMIRYSATLFVQEKLLGLMSLPTKEKYEELKKKRKQEQERRLQQERLAAQEALKRRQEAEKICSPANGELPQARRAQRMTKASGWLPSAESV-------HSR------------SELED-----PLLQQIQNIQSFLRQAREAQKADEVAMLEENLRQLQDEYD 505
[Close]
BLAST of Rabenosyn-5 vs. Ensembl Medaka
Match: rbsn (rabenosyn, RAB effector [Source:NCBI gene;Acc:101169204])

HSP 1 Score: 118.242 bits (295), Expect = 2.217e-27
Identity = 144/573 (25.13%), Postives = 232/573 (40.49%), Query Frame = 3 
Query:  105 ITEGFICPECMKKCVSLKNLXXXXXXXXXXXXXXPSDQSGFLGIIKKAKKTFEEILDAKDGELIFSNNLSSNTLKNENNDMDDDPFVSHAFYEEPNIKPQPLGITVNRTEEFLKIRRTKLLRSAIETSSLILKIEKLISFQ---SNASNRERKNFEQSIVEWVKDDLVPMCPMCGGKFGINSPISTYSDVPAVLSSNIEQQNTRKQSRFKTAFINFMDMEIEGSGLLIRKKHHCRLCGCVICAHCSYILSAGEASKLVNAINSRFELKESILEESRKILWKNDSQNSLDSIKSK---IKTQTVYSIRCCGNCKSLIEAKWNQLERRVCDSEIVDLYEELMENRNKVSQLIPEYNTMCQSLCLGETEYSYQRANELRSEIVQFCQKIDAIGNKFKS---RTTTNGSEREATLVKSIYRNTFLFLQNNFATLKQLP-----------QEDKLEEIVNQRLIEIKKKAATMQKNRSPE----IEKYLVKSNNDDSGWAPTIPSNCGYHNEGHNRNTNNPFECDSTDSNTEENTRLTALALQMENVRQYIELAHQAKKVQEVKMLQNNMLDLKLEYD 1751
            + EGF+CP C+K   S   LQ H+++ H           G L  + +  K  ++ L  +DGE    + L + + ++       DP++          +PQ LG T +  + F K R  ++    IE + LI+++EKL SF    S+++        +S+V WV D  VP CP CG KF I +                                               ++HHCRLCG ++C  C   +    A    NA  S  +     L            + S+ S+ S    ++ +    IRCC +C   +  K  +L+ +    +IV LYE LM    KV +  P+Y  M +SL  GET Y+   A  LR E+ ++ + IDA+  K  +   +       +   L K I  +  LF+Q     L  LP           ++ + E  + Q  +E  K+    +K  SP      +    +     SGW P+  S        H+R            S  E+      L  Q++N++ ++  A +A+K  EV ML+ N+  L+ EYD
Sbjct:   11 VKEGFLCPLCLKDLQSFYQLQGHYEEEHSGDDRH---VRGQLKSLVQKAKKAKDKLLKRDGE----DRLDTGSYESFYYG-GVDPYM---------WEPQELGATRSHLDIFKKHRAARIDHYVIEVNKLIIRLEKLTSFDRVNSDSAKIRGVLLFKSVVSWVNDSDVPFCPDCGNKFNIRN-----------------------------------------------RRHHCRLCGSIMCRRCMEFVPLPLARMHQNA--SEVQTSTQTLPAGGGSSGMGSRRGSISSLSSVTSMLEEKDDEKIRCCHHCMDTLLKKQQKLDEKDNIPDIVKLYERLMMCMVKVDEKAPDYIRMAESLNAGETTYNLDTAGGLRLEVQKYYELIDALSKKILTLGLKDEPPPHPKALQLQKMIRYSATLFVQEKLLGLMSLPTKEKYEELKKKRKQEQERRLQQERLEALKRRQEAEKICSPANGELPQARRAQRMTKASGWLPSAESV-------HSR------------SELED-----PLLQQIQNIQSFLRQAREAQKADEVAMLEENLRQLQDEYD 493
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BLAST of Rabenosyn-5 vs. Planmine SMEST
Match: SMESG000056864.1 (SMESG000056864.1)

HSP 1 Score: 1114.37 bits (2881), Expect = 0.000e+0
Identity = 557/559 (99.64%), Postives = 559/559 (100.00%), Query Frame = 3 
Query:   99 MSITEGFICPECMKKCVSLKNLXXXXXXXXXXXXXXPSDQSGFLGIIKKAKKTFEEILDAKDGELIFSNNLSSNTLKNENNDMDDDPFVSHAFYEEPNIKPQPLGITVNRTEEFLKIRRTKLLRSAIETSSLILKIEKLISFQSNASNRERKNFEQSIVEWVKDDLVPMCPMCGGKFGINSPISTYSDVPAVLSSNIEQQNTRKQSRFKTAFINFMDMEIEGSGLLIRKKHHCRLCGCVICAHCSYILSAGEASKLVNAINSRFELKESILEESRKILWKNDSQNSLDSIKSKIKTQTVYSIRCCGNCKSLIEAKWNQLERRVCDSEIVDLYEELMENRNKVSQLIPEYNTMCQSLCLGETEYSYQRANELRSEIVQFCQKIDAIGNKFKSRTTTNGSEREATLVKSIYRNTFLFLQNNFATLKQLPQEDKLEEIVNQRLIEIKKKAATMQKNRSPEIEKYLVKSNNDDSGWAPTIPSNCGYHNEGHNRNTNNPFECDSTDSNTEENTRLTALALQMENVRQYIELAHQAKKVQEVKMLQNNMLDLKLEYDALRKKLKI 1775
            MSITEGFICPECMKKCVSLKNLQDHFQQIHIDQIEIPSDQSGFLGIIKKAKKTFEEILDAKDGELIFSNNLSSNTLKNENNDMD+DPFVSHAFYEEPNIKPQPLGITVNRTEEFLKIRRTKLLRSAIETSSLILKIEKLISFQSNASNRERKNFEQSIVEWVKDDLVPMCPMCGGKFGINSPISTYSDVPAVLSSNIEQQNTRKQSRFKTAFINFMDMEIEGSGLLIRKKHHCRLCGCVICAHCSYILSAGEASKLVNAINSRFELKES+LEESRKILWKNDSQNSLDSIKSKIKTQTVYSIRCCGNCKSLIEAKWNQLERRVCDSEIVDLYEELMENRNKVSQLIPEYNTMCQSLCLGETEYSYQRANELRSEIVQFCQKIDAIGNKFKSRTTTNGSEREATLVKSIYRNTFLFLQNNFATLKQLPQEDKLEEIVNQRLIEIKKKAATMQKNRSPEIEKYLVKSNNDDSGWAPTIPSNCGYHNEGHNRNTNNPFECDSTDSNTEENTRLTALALQMENVRQYIELAHQAKKVQEVKMLQNNMLDLKLEYDALRKKLKI
Sbjct:    1 MSITEGFICPECMKKCVSLKNLQDHFQQIHIDQIEIPSDQSGFLGIIKKAKKTFEEILDAKDGELIFSNNLSSNTLKNENNDMDNDPFVSHAFYEEPNIKPQPLGITVNRTEEFLKIRRTKLLRSAIETSSLILKIEKLISFQSNASNRERKNFEQSIVEWVKDDLVPMCPMCGGKFGINSPISTYSDVPAVLSSNIEQQNTRKQSRFKTAFINFMDMEIEGSGLLIRKKHHCRLCGCVICAHCSYILSAGEASKLVNAINSRFELKESLLEESRKILWKNDSQNSLDSIKSKIKTQTVYSIRCCGNCKSLIEAKWNQLERRVCDSEIVDLYEELMENRNKVSQLIPEYNTMCQSLCLGETEYSYQRANELRSEIVQFCQKIDAIGNKFKSRTTTNGSEREATLVKSIYRNTFLFLQNNFATLKQLPQEDKLEEIVNQRLIEIKKKAATMQKNRSPEIEKYLVKSNNDDSGWAPTIPSNCGYHNEGHNRNTNNPFECDSTDSNTEENTRLTALALQMENVRQYIELAHQAKKVQEVKMLQNNMLDLKLEYDALRKKLKI 559
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BLAST of Rabenosyn-5 vs. Planmine SMEST
Match: SMESG000056864.1 (SMESG000056864.1)

HSP 1 Score: 1087.4 bits (2811), Expect = 0.000e+0
Identity = 545/547 (99.63%), Postives = 547/547 (100.00%), Query Frame = 3 
Query:  135 MKKCVSLKNLXXXXXXXXXXXXXXPSDQSGFLGIIKKAKKTFEEILDAKDGELIFSNNLSSNTLKNENNDMDDDPFVSHAFYEEPNIKPQPLGITVNRTEEFLKIRRTKLLRSAIETSSLILKIEKLISFQSNASNRERKNFEQSIVEWVKDDLVPMCPMCGGKFGINSPISTYSDVPAVLSSNIEQQNTRKQSRFKTAFINFMDMEIEGSGLLIRKKHHCRLCGCVICAHCSYILSAGEASKLVNAINSRFELKESILEESRKILWKNDSQNSLDSIKSKIKTQTVYSIRCCGNCKSLIEAKWNQLERRVCDSEIVDLYEELMENRNKVSQLIPEYNTMCQSLCLGETEYSYQRANELRSEIVQFCQKIDAIGNKFKSRTTTNGSEREATLVKSIYRNTFLFLQNNFATLKQLPQEDKLEEIVNQRLIEIKKKAATMQKNRSPEIEKYLVKSNNDDSGWAPTIPSNCGYHNEGHNRNTNNPFECDSTDSNTEENTRLTALALQMENVRQYIELAHQAKKVQEVKMLQNNMLDLKLEYDALRKKLKI 1775
            MKKCVSLKNLQDHFQQIHIDQIEIPSDQSGFLGIIKKAKKTFEEILDAKDGELIFSNNLSSNTLKNENNDMD+DPFVSHAFYEEPNIKPQPLGITVNRTEEFLKIRRTKLLRSAIETSSLILKIEKLISFQSNASNRERKNFEQSIVEWVKDDLVPMCPMCGGKFGINSPISTYSDVPAVLSSNIEQQNTRKQSRFKTAFINFMDMEIEGSGLLIRKKHHCRLCGCVICAHCSYILSAGEASKLVNAINSRFELKES+LEESRKILWKNDSQNSLDSIKSKIKTQTVYSIRCCGNCKSLIEAKWNQLERRVCDSEIVDLYEELMENRNKVSQLIPEYNTMCQSLCLGETEYSYQRANELRSEIVQFCQKIDAIGNKFKSRTTTNGSEREATLVKSIYRNTFLFLQNNFATLKQLPQEDKLEEIVNQRLIEIKKKAATMQKNRSPEIEKYLVKSNNDDSGWAPTIPSNCGYHNEGHNRNTNNPFECDSTDSNTEENTRLTALALQMENVRQYIELAHQAKKVQEVKMLQNNMLDLKLEYDALRKKLKI
Sbjct:    1 MKKCVSLKNLQDHFQQIHIDQIEIPSDQSGFLGIIKKAKKTFEEILDAKDGELIFSNNLSSNTLKNENNDMDNDPFVSHAFYEEPNIKPQPLGITVNRTEEFLKIRRTKLLRSAIETSSLILKIEKLISFQSNASNRERKNFEQSIVEWVKDDLVPMCPMCGGKFGINSPISTYSDVPAVLSSNIEQQNTRKQSRFKTAFINFMDMEIEGSGLLIRKKHHCRLCGCVICAHCSYILSAGEASKLVNAINSRFELKESLLEESRKILWKNDSQNSLDSIKSKIKTQTVYSIRCCGNCKSLIEAKWNQLERRVCDSEIVDLYEELMENRNKVSQLIPEYNTMCQSLCLGETEYSYQRANELRSEIVQFCQKIDAIGNKFKSRTTTNGSEREATLVKSIYRNTFLFLQNNFATLKQLPQEDKLEEIVNQRLIEIKKKAATMQKNRSPEIEKYLVKSNNDDSGWAPTIPSNCGYHNEGHNRNTNNPFECDSTDSNTEENTRLTALALQMENVRQYIELAHQAKKVQEVKMLQNNMLDLKLEYDALRKKLKI 547
The following BLAST results are available for this feature:
BLAST of Rabenosyn-5 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 3
Match NameE-valueIdentityDescription
RBSN1.581e-3425.57rabenosyn, RAB effector [Source:HGNC Symbol;Acc:HG... [more]
RBSN1.581e-3425.57rabenosyn, RAB effector [Source:HGNC Symbol;Acc:HG... [more]
RBSN8.465e-831.09rabenosyn, RAB effector [Source:HGNC Symbol;Acc:HG... [more]
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BLAST of Rabenosyn-5 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2
Match NameE-valueIdentityDescription
rabs-52.750e-2522.89RABenoSyn (Trafficking protein) homolog [Source:U... [more]
rabs-51.034e-2423.18RABenoSyn (Trafficking protein) homolog [Source:U... [more]
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BLAST of Rabenosyn-5 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1
Match NameE-valueIdentityDescription
Rbsn-52.674e-2422.42gene:FBgn0261064 transcript:FBtr0079581[more]
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BLAST of Rabenosyn-5 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
rbsn1.763e-3525.39rabenosyn, RAB effector [Source:ZFIN;Acc:ZDB-GENE-... [more]
rbsn1.165e-3425.17rabenosyn, RAB effector [Source:ZFIN;Acc:ZDB-GENE-... [more]
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BLAST of Rabenosyn-5 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
RBSN5.081e-3825.89rabenosyn, RAB effector [Source:NCBI gene;Acc:1004... [more]
RBSN3.926e-3726.09rabenosyn, RAB effector [Source:NCBI gene;Acc:1004... [more]
RBSN6.809e-3726.09rabenosyn, RAB effector [Source:NCBI gene;Acc:1004... [more]
RBSN1.464e-3625.83rabenosyn, RAB effector [Source:NCBI gene;Acc:1004... [more]
RBSN6.675e-3625.94rabenosyn, RAB effector [Source:NCBI gene;Acc:1004... [more]
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BLAST of Rabenosyn-5 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 2
Match NameE-valueIdentityDescription
Rbsn1.142e-3525.66rabenosyn, RAB effector [Source:MGI Symbol;Acc:MGI... [more]
Rbsn6.337e-1032.81rabenosyn, RAB effector [Source:MGI Symbol;Acc:MGI... [more]
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BLAST of Rabenosyn-5 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 2
Match NameE-valueIdentityDescription
sp|Q80Y56|RBNS5_MOUSE7.989e-3525.66Rabenosyn-5 OS=Mus musculus OX=10090 GN=Rbsn PE=1 ... [more]
sp|Q9H1K0|RBNS5_HUMAN7.594e-3425.57Rabenosyn-5 OS=Homo sapiens OX=9606 GN=RBSN PE=1 S... [more]
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BLAST of Rabenosyn-5 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0L8I5T73.456e-4928.65Uncharacterized protein OS=Octopus bimaculoides OX... [more]
A0A0R3VVR02.168e-4729.34C2H2-type domain-containing protein OS=Taenia asia... [more]
V4A1G33.016e-4627.34Uncharacterized protein OS=Lottia gigantea OX=2251... [more]
A0A4V3SDB54.704e-4627.53C2H2-type domain-containing protein OS=Opisthorchi... [more]
C3YPL07.630e-4625.59Uncharacterized protein OS=Branchiostoma floridae ... [more]
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BLAST of Rabenosyn-5 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
rbsn3.587e-3425.89rabenosyn, RAB effector [Source:NCBI gene;Acc:1030... [more]
rbsn5.408e-3425.95rabenosyn, RAB effector [Source:NCBI gene;Acc:1030... [more]
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BLAST of Rabenosyn-5 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
rbsn1.881e-3024.00rabenosyn, RAB effector [Source:ZFIN;Acc:ZDB-GENE-... [more]
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BLAST of Rabenosyn-5 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Rabenosyn-5 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO390447.897e-2125.15Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Rabenosyn-5 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 2
Match NameE-valueIdentityDescription
rbsn7.158e-3126.08rabenosyn, RAB effector [Source:NCBI gene;Acc:1011... [more]
rbsn2.217e-2725.13rabenosyn, RAB effector [Source:NCBI gene;Acc:1011... [more]
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BLAST of Rabenosyn-5 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 2
Match NameE-valueIdentityDescription
SMESG000056864.10.000e+099.64SMESG000056864.1[more]
SMESG000056864.10.000e+099.63SMESG000056864.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30019882 ID=SMED30019882|Name=Rabenosyn-5|organism=Schmidtea mediterranea sexual|type=transcript|length=1786bp
GCTTTCTTTATAATGACTGCGAAATTGATATAAAATTTTTCTAATATTAA
ATATTATTTTCGAACTTAAAGATCACTAATTTATATATATTAAATTTTAT
GTCGATAACAGAAGGATTTATTTGTCCAGAATGCATGAAAAAATGTGTTT
CATTGAAAAATTTACAGGATCATTTTCAGCAAATTCACATCGATCAAATT
GAAATCCCGAGTGATCAAAGTGGATTTCTAGGTATTATAAAGAAAGCGAA
AAAAACTTTTGAAGAAATTTTAGACGCTAAGGATGGTGAACTTATATTTT
CCAATAATTTATCATCGAACACATTGAAAAATGAAAATAATGATATGGAT
GATGATCCTTTTGTTTCACATGCATTCTACGAAGAGCCTAATATCAAACC
CCAACCACTTGGAATTACTGTAAATCGCACTGAAGAATTTTTAAAAATCC
GAAGAACCAAATTGTTACGTTCAGCAATTGAAACGAGTTCTTTAATACTT
AAAATAGAAAAATTAATTTCATTCCAATCTAATGCGAGTAATCGTGAAAG
AAAAAACTTTGAGCAATCTATTGTCGAGTGGGTTAAAGATGACCTTGTAC
CAATGTGTCCTATGTGCGGTGGGAAATTCGGCATTAATTCACCAATAAGT
ACATATTCTGATGTACCAGCTGTATTATCCAGTAATATTGAACAACAAAA
TACCAGAAAACAATCGAGATTTAAAACTGCTTTTATTAATTTTATGGATA
TGGAAATTGAAGGTTCAGGATTATTGATACGAAAAAAACATCATTGTCGA
CTTTGTGGGTGCGTAATATGTGCACACTGCTCATACATATTAAGCGCTGG
AGAAGCGTCTAAGTTGGTCAATGCTATAAATTCACGATTTGAATTAAAAG
AATCTATATTGGAAGAATCTAGAAAAATTCTATGGAAGAACGATAGTCAA
AACAGTTTAGACTCTATCAAATCCAAAATTAAAACTCAAACTGTCTACAG
TATTCGCTGCTGTGGAAATTGCAAATCCCTTATAGAGGCAAAATGGAATC
AGTTAGAACGGCGTGTTTGCGACTCAGAAATAGTAGATTTATACGAAGAA
CTAATGGAAAATAGAAATAAAGTATCTCAATTAATACCCGAATACAATAC
AATGTGCCAAAGTTTATGTTTAGGAGAAACCGAATACAGTTATCAGAGAG
CTAATGAACTTCGATCAGAAATAGTTCAATTTTGCCAAAAAATAGACGCC
ATAGGAAATAAATTTAAATCAAGAACTACCACTAACGGAAGTGAACGGGA
AGCTACTCTAGTCAAATCAATTTATAGAAATACTTTCTTGTTTTTACAAA
ATAATTTTGCTACTCTTAAACAGCTACCTCAAGAAGATAAATTAGAAGAA
ATAGTAAACCAACGATTAATAGAAATTAAGAAAAAAGCAGCAACAATGCA
AAAAAACCGATCTCCTGAAATTGAGAAGTATTTAGTGAAAAGTAATAATG
ATGATTCAGGCTGGGCTCCAACCATCCCCAGTAACTGTGGTTATCATAAC
GAGGGCCACAACCGGAATACCAATAATCCGTTCGAATGTGACAGTACCGA
TTCGAATACCGAAGAAAATACTCGCTTAACTGCTCTGGCATTGCAAATGG
AAAATGTCCGGCAATATATTGAACTTGCCCACCAAGCTAAAAAGGTTCAA
GAAGTGAAGATGCTACAGAACAATATGCTAGATTTGAAATTAGAATACGA
TGCGTTGCGGAAAAAGTTGAAAATTTAAATCACTGT
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protein sequence of SMED30019882-orf-1

>SMED30019882-orf-1 ID=SMED30019882-orf-1|Name=SMED30019882-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=560bp
MSITEGFICPECMKKCVSLKNLQDHFQQIHIDQIEIPSDQSGFLGIIKKA
KKTFEEILDAKDGELIFSNNLSSNTLKNENNDMDDDPFVSHAFYEEPNIK
PQPLGITVNRTEEFLKIRRTKLLRSAIETSSLILKIEKLISFQSNASNRE
RKNFEQSIVEWVKDDLVPMCPMCGGKFGINSPISTYSDVPAVLSSNIEQQ
NTRKQSRFKTAFINFMDMEIEGSGLLIRKKHHCRLCGCVICAHCSYILSA
GEASKLVNAINSRFELKESILEESRKILWKNDSQNSLDSIKSKIKTQTVY
SIRCCGNCKSLIEAKWNQLERRVCDSEIVDLYEELMENRNKVSQLIPEYN
TMCQSLCLGETEYSYQRANELRSEIVQFCQKIDAIGNKFKSRTTTNGSER
EATLVKSIYRNTFLFLQNNFATLKQLPQEDKLEEIVNQRLIEIKKKAATM
QKNRSPEIEKYLVKSNNDDSGWAPTIPSNCGYHNEGHNRNTNNPFECDST
DSNTEENTRLTALALQMENVRQYIELAHQAKKVQEVKMLQNNMLDLKLEY
DALRKKLKI*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0003676nucleic acid binding
GO:0046872metal ion binding
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
Vocabulary: INTERPRO
TermDefinition
IPR036531Rbsn_Rab-bd_sf
IPR000306Znf_FYVE
IPR021565Rbsn_Rab_binding_dom
IPR013083Znf_RING/FYVE/PHD
IPR007087Znf_C2H2
IPR011011Znf_FYVE_PHD
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 454..477
NoneNo IPR availableGENE3DG3DSA:4.10.860.20coord: 408..474
e-value: 8.6E-10
score: 40.1
NoneNo IPR availablePANTHERPTHR13510FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATEDcoord: 74..402
IPR000306FYVE zinc fingerSMARTSM00064fyve_4coord: 74..232
e-value: 1.8E-4
score: 27.6
IPR000306FYVE zinc fingerPFAMPF01363FYVEcoord: 78..229
e-value: 1.4E-9
score: 37.9
IPR013083Zinc finger, RING/FYVE/PHD-typeGENE3DG3DSA:3.30.40.10coord: 133..181
e-value: 8.4E-6
score: 27.6
IPR021565Rabenosyn, Rab binding domainPFAMPF11464Rbsncoord: 433..470
e-value: 2.6E-7
score: 30.2
IPR036531Rabenosyn, Rab binding domain superfamilySUPERFAMILYSSF140125Rabenosyn-5 Rab-binding domain-likecoord: 419..471
IPR011011Zinc finger, FYVE/PHD-typeSUPERFAMILYSSF57903FYVE/PHD zinc fingercoord: 145..167