Peptidase M60 domain-containing protein
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30019854 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 1
Homology
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Human
Match: TCAF2C (TRPM8 channel associated factor 2C [Source:HGNC Symbol;Acc:HGNC:53641]) HSP 1 Score: 146.362 bits (368), Expect = 2.068e-35 Identity = 104/373 (27.88%), Postives = 177/373 (47.45%), Query Frame = 2
Query: 1943 GLYLYPRLKTPVKIIQSK-STRCYIYVNHHHFNIADKSEVTKWPVTYKYFTIERGKWETIQFPFGGLMSISCNENND--KVEIIFKNVIQIPYY--DRRNKDEW-IQKQKIESPWAVLAGDAVVFILASTAIRNLADPETILQMYDSMFKEEFHLRGTSFPFSRRGIVSSDIQIGVGYMHSGYPIGTQIYHNNNPYKSGYFFNKEILKKDGAWGLMHEMGHNLQ-XXXXXXXXXXXXXXXIFSIIATESMTNQNSWSQTSGWFHERLTI----ERVQKYLISGTFDNNWRENHFVALCIYAQIKNYFGWEFYAQVFRRYNALTHKQRSISEDEKIQLWIKITSEISGMNLCPLYELWKWPITNQTEQELSKLP 3028
GLYL V + ++ S + + H ++ ++++ PV ++R + ++ +GGL+ + + + V + + + PYY + + +EW Q Q+ +PW LA D ++ + +T ++ L DPE +L+++D M + L FPF R + +D+QI G+MHSGYPI + N+ ++ G WG +HE+GHN Q G T E T N++S+ E++ HE L+ R++ +L G +W N + AL Y Q++ FGWE + Q+F Y L+H + ++ LW+K SE NL P +E W WPI + L+ LP
Sbjct: 341 GLYLLEGQNAEVSLSEAAASAGLRVQIGCHTDDLTKARKLSRAPVVTHQCWMDRTE-RSVSCLWGGLLYVIVPKGSQLGPVPVTIRGAVPAPYYKLGKTSLEEWKRQMQENLAPWGELATDNIILTVPTTNLQALKDPEPVLRLWDEMMQAVARLAAEPFPFRRPERIVADVQISAGWMHSGYPIMCHLESVKE------IINEMDMRSRGVWGPIHELGHNQQWHGWEFPPHTTEATCNLWSVYVHETVLG-----IPRAQAHEALSPPERERRIKAHLGKGAPLCDW--NVWTALETYLQLQQAFGWEPFTQLFAEYQTLSHLPK--DNTGRMNLWVKKFSEKVKKNLVPFFEAWGWPIQKEVADSLASLP 697
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Human
Match: TCAF2 (TRPM8 channel associated factor 2 [Source:HGNC Symbol;Acc:HGNC:26878]) HSP 1 Score: 147.132 bits (370), Expect = 2.782e-35 Identity = 103/373 (27.61%), Postives = 176/373 (47.18%), Query Frame = 2
Query: 1943 GLYLYPRLKTPVKIIQSK-STRCYIYVNHHHFNIADKSEVTKWPVTYKYFTIERGKWETIQFPFGGLMSISCNENN--DKVEIIFKNVIQIPYY--DRRNKDEW-IQKQKIESPWAVLAGDAVVFILASTAIRNLADPETILQMYDSMFKEEFHLRGTSFPFSRRGIVSSDIQIGVGYMHSGYPIGTQIYHNNNPYKSGYFFNKEILKKDGAWGLMHEMGHNLQXXX-XXXXXXXXXXXXIFSIIATESMTNQNSWSQTSGWFHERLTI----ERVQKYLISGTFDNNWRENHFVALCIYAQIKNYFGWEFYAQVFRRYNALTHKQRSISEDEKIQLWIKITSEISGMNLCPLYELWKWPITNQTEQELSKLP 3028
GLYL V + ++ S + + H ++ ++++ PV ++R + ++ +GGL+ + + + V + + + PYY + + +EW Q Q+ +PW LA D ++ + +T ++ L DPE +L+++D M + L FPF R + +D+QI G+MHSGYPI + N+ ++ G WG +HE+GHN Q T E T N++S+ E++ HE L+ R++ +L G +W N + AL Y Q++ FGWE + Q+F Y L+H + ++ LW+K SE NL P +E W WPI + L+ LP
Sbjct: 548 GLYLLEGQNAEVSLSEAAASAGLRVQIGCHTDDLTKARKLSRAPVVTHQCWMDRTE-RSVSCLWGGLLYVIVPKGSQLGPVPVTIRGAVPAPYYKLGKTSLEEWKRQMQENLAPWGELATDNIILTVPTTNLQALKDPEPVLRLWDEMMQAVARLAAEPFPFRRPERIVADVQISAGWMHSGYPIMCHLESVKE------IINEMDMRSRGVWGPIHELGHNQQRHGWEFPPHTTEATCNLWSVYVHETVLG-----IPRAQAHEALSPPERERRIKAHLGKGAPLCDW--NVWTALETYLQLQEAFGWEPFTQLFAEYQTLSHLPK--DNTGRMNLWVKKFSEKVKKNLVPFFEAWGWPIQKEVADSLASLP 904
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Human
Match: TCAF2 (TRPM8 channel associated factor 2 [Source:HGNC Symbol;Acc:HGNC:26878]) HSP 1 Score: 146.747 bits (369), Expect = 3.214e-35 Identity = 103/373 (27.61%), Postives = 176/373 (47.18%), Query Frame = 2
Query: 1943 GLYLYPRLKTPVKIIQSK-STRCYIYVNHHHFNIADKSEVTKWPVTYKYFTIERGKWETIQFPFGGLMSISCNENND--KVEIIFKNVIQIPYY--DRRNKDEW-IQKQKIESPWAVLAGDAVVFILASTAIRNLADPETILQMYDSMFKEEFHLRGTSFPFSRRGIVSSDIQIGVGYMHSGYPIGTQIYHNNNPYKSGYFFNKEILKKDGAWGLMHEMGHNLQXXX-XXXXXXXXXXXXIFSIIATESMTNQNSWSQTSGWFHERLTI----ERVQKYLISGTFDNNWRENHFVALCIYAQIKNYFGWEFYAQVFRRYNALTHKQRSISEDEKIQLWIKITSEISGMNLCPLYELWKWPITNQTEQELSKLP 3028
GLYL V + ++ S + + H ++ ++++ PV ++R + ++ +GGL+ + + + V + + + PYY + + +EW Q Q+ +PW LA D ++ + +T ++ L DPE +L+++D M + L FPF R + +D+QI G+MHSGYPI + N+ ++ G WG +HE+GHN Q T E T N++S+ E++ HE L+ R++ +L G +W N + AL Y Q++ FGWE + Q+F Y L+H + ++ LW+K SE NL P +E W WPI + L+ LP
Sbjct: 444 GLYLLEGQNAEVSLSEAAASAGLRVQIGCHTDDLTKARKLSRAPVVTHQCWMDRTE-RSVSCLWGGLLYVIVPKGSQLGPVPVTIRGAVPAPYYKLGKTSLEEWKRQMQENLAPWGELATDNIILTVPTTNLQALKDPEPVLRLWDEMMQAVARLAAEPFPFRRPERIVADVQISAGWMHSGYPIMCHLESVKE------IINEMDMRSRGVWGPIHELGHNQQRHGWEFPPHTTEATCNLWSVYVHETVLG-----IPRAQAHEALSPPERERRIKAHLGKGAPLCDW--NVWTALETYLQLQEAFGWEPFTQLFAEYQTLSHLPK--DNTGRMNLWVKKFSEKVKKNLVPFFEAWGWPIQKEVADSLASLP 800
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Human
Match: TCAF2 (TRPM8 channel associated factor 2 [Source:HGNC Symbol;Acc:HGNC:26878]) HSP 1 Score: 146.747 bits (369), Expect = 3.214e-35 Identity = 103/373 (27.61%), Postives = 176/373 (47.18%), Query Frame = 2
Query: 1943 GLYLYPRLKTPVKIIQSK-STRCYIYVNHHHFNIADKSEVTKWPVTYKYFTIERGKWETIQFPFGGLMSISCNENND--KVEIIFKNVIQIPYY--DRRNKDEW-IQKQKIESPWAVLAGDAVVFILASTAIRNLADPETILQMYDSMFKEEFHLRGTSFPFSRRGIVSSDIQIGVGYMHSGYPIGTQIYHNNNPYKSGYFFNKEILKKDGAWGLMHEMGHNLQXXX-XXXXXXXXXXXXIFSIIATESMTNQNSWSQTSGWFHERLTI----ERVQKYLISGTFDNNWRENHFVALCIYAQIKNYFGWEFYAQVFRRYNALTHKQRSISEDEKIQLWIKITSEISGMNLCPLYELWKWPITNQTEQELSKLP 3028
GLYL V + ++ S + + H ++ ++++ PV ++R + ++ +GGL+ + + + V + + + PYY + + +EW Q Q+ +PW LA D ++ + +T ++ L DPE +L+++D M + L FPF R + +D+QI G+MHSGYPI + N+ ++ G WG +HE+GHN Q T E T N++S+ E++ HE L+ R++ +L G +W N + AL Y Q++ FGWE + Q+F Y L+H + ++ LW+K SE NL P +E W WPI + L+ LP
Sbjct: 444 GLYLLEGQNAEVSLSEAAASAGLRVQIGCHTDDLTKARKLSRAPVVTHQCWMDRTE-RSVSCLWGGLLYVIVPKGSQLGPVPVTIRGAVPAPYYKLGKTSLEEWKRQMQENLAPWGELATDNIILTVPTTNLQALKDPEPVLRLWDEMMQAVARLAAEPFPFRRPERIVADVQISAGWMHSGYPIMCHLESVKE------IINEMDMRSRGVWGPIHELGHNQQRHGWEFPPHTTEATCNLWSVYVHETVLG-----IPRAQAHEALSPPERERRIKAHLGKGAPLCDW--NVWTALETYLQLQEAFGWEPFTQLFAEYQTLSHLPK--DNTGRMNLWVKKFSEKVKKNLVPFFEAWGWPIQKEVADSLASLP 800
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Human
Match: TCAF1 (TRPM8 channel associated factor 1 [Source:HGNC Symbol;Acc:HGNC:22201]) HSP 1 Score: 137.502 bits (345), Expect = 2.705e-32 Identity = 101/370 (27.30%), Postives = 175/370 (47.30%), Query Frame = 2
Query: 1943 GLYLYPRLKTPVKIIQSK-STRCYIYVNHHHFNIADKSEVTKWPVTYKYFTIERGKWETIQFPFGGLMSISCNENN--DKVEIIFKNVIQIPYY--DRRNKDEWIQK-QKIESPWAVLAGDAVVFILASTAIRNLADPETILQMYDSMFKEEFHLRGTSFPFSRRGIVSSDIQIGVGYMHSGYPIGTQIYHNNNPYKSGYFFNKEILKKDGAWGLMHEMGHNLQXXX-XXXXXXXXXXXXIFSIIATESMTN-QNSWSQTSGWFHERLTIERVQKYLISGTFDNNWRENHFVALCIYAQIKNYFGWEFYAQVFRRYNALTHKQRSISEDEKIQLWIKITSEISGMNLCPLYELWKWPITNQTEQELSKLP 3028
GLY+ R V + ++ S I + H ++ S++ + P+ +++ ++I +GGL+ I +N+ V + K + PYY +EW ++ Q+ PW LA D ++ + + +R L +PE +L+++D + + L FP + +D+QI VG+MH+GYPI + N+++++ G WG +HE+G N Q T E T N++ + E++ S + + W R +RV+ YL G NW N + AL Y Q++ FGWE + ++F Y T+ +K+ LW+K+ S NL P +E W WPI + L+ LP
Sbjct: 548 GLYIPGRQIIEVSLPEAAASADLKIQIGCHTDDLTRASKLFRGPLVINRCCLDKPT-KSITCLWGGLLYIIVPQNSKLGSVPVTVKGAVHAPYYKLGETTLEEWKRRIQENPGPWGELATDNIILTVPTANLRTLENPEPLLRLWDEVMQAVARLGAEPFPLRLPQRIVADVQISVGWMHAGYPIMCHLESVQE------LINEKLIRTKGLWGPVHELGRNQQRQEWEFPPHTTEATCNLWCVYVHETVLGIPRSRANIALWPPVRE--KRVRIYLSKGPNVKNW--NAWTALETYLQLQEAFGWEPFIRLFTEYRNQTN--LPTENVDKMNLWVKMFSHQVQKNLAPFFEAWAWPIQKEVATSLAYLP 904
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Celegans
Match: cam-1 (Tyrosine-protein kinase receptor cam-1 [Source:UniProtKB/Swiss-Prot;Acc:G5EGK5]) HSP 1 Score: 63.929 bits (154), Expect = 6.028e-10 Identity = 37/88 (42.05%), Postives = 48/88 (54.55%), Query Frame = 2
Query: 344 NWCKDSDKGTEYLGDISHTKSGKLCQPWI-----NFGTHRAYSFPERNLKFAGNKCRNPDMSKV-PWCYYSNNYQREDCNVPRCDKEI 589
+WC + GT+Y G ++ T SGK C PWI +F HR FPE L + N CRNP K PWCY Q E C+VP+C ++
Sbjct: 193 HWCY-VNSGTQYEGTVAQTSSGKQCAPWIDSTSRDFNVHR---FPE--LMNSKNYCRNPGGKKSRPWCYSKPMGQEEYCDVPQCPSDM 274
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Celegans
Match: cam-1 (Tyrosine-protein kinase receptor cam-1 [Source:UniProtKB/Swiss-Prot;Acc:G5EGK5]) HSP 1 Score: 63.929 bits (154), Expect = 6.103e-10 Identity = 37/88 (42.05%), Postives = 48/88 (54.55%), Query Frame = 2
Query: 344 NWCKDSDKGTEYLGDISHTKSGKLCQPWI-----NFGTHRAYSFPERNLKFAGNKCRNPDMSKV-PWCYYSNNYQREDCNVPRCDKEI 589
+WC + GT+Y G ++ T SGK C PWI +F HR FPE L + N CRNP K PWCY Q E C+VP+C ++
Sbjct: 326 HWCY-VNSGTQYEGTVAQTSSGKQCAPWIDSTSRDFNVHR---FPE--LMNSKNYCRNPGGKKSRPWCYSKPMGQEEYCDVPQCPSDM 407
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Celegans
Match: cam-1 (Tyrosine-protein kinase receptor cam-1 [Source:UniProtKB/Swiss-Prot;Acc:G5EGK5]) HSP 1 Score: 63.929 bits (154), Expect = 6.331e-10 Identity = 37/88 (42.05%), Postives = 48/88 (54.55%), Query Frame = 2
Query: 344 NWCKDSDKGTEYLGDISHTKSGKLCQPWI-----NFGTHRAYSFPERNLKFAGNKCRNPDMSKV-PWCYYSNNYQREDCNVPRCDKEI 589
+WC + GT+Y G ++ T SGK C PWI +F HR FPE L + N CRNP K PWCY Q E C+VP+C ++
Sbjct: 352 HWCY-VNSGTQYEGTVAQTSSGKQCAPWIDSTSRDFNVHR---FPE--LMNSKNYCRNPGGKKSRPWCYSKPMGQEEYCDVPQCPSDM 433
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Zebrafish
Match: si:ch211-210b2.3 (si:ch211-210b2.3 [Source:ZFIN;Acc:ZDB-GENE-131122-13]) HSP 1 Score: 150.984 bits (380), Expect = 1.149e-36 Identity = 124/430 (28.84%), Postives = 200/430 (46.51%), Query Frame = 2
Query: 1805 LLSEIGKDLI-----PPALSLYPGKFQSTNPPFVNIKMKL--NLLYKYEVAPLGLYLYPRLKTPVKIIQSK-STRCYIYVNHHHFNIADKSEVTKWPVTYKYFTIERGKWETIQFPFGGLMSISCNENN--DKVEIIFKNVIQIPYYDRRNKD--EWIQK-QKIESPWAVLAGDAVVFILASTAIRNLADPETILQMYDSMFKEEFHLRGTSFPFSRRGIVSSDIQIGVGYMHSGYPIGTQIYHNNNPYKSGYFFNKEILKKDGAWGLMHEMGHNLQXXX-XXXXXXXXXXXXIFSIIATESMTNQNSWSQTSGWFHERLTI----ERVQKYLISGTFDNNWRENHFVALCIYAQIKNYFGWEFYAQVFRRYNALTHKQRSISEDE--KIQLWIKITSEISGMNLCPLYELWKWPITNQTEQELSKLPMF 3034
++ IGK++ P AL Y K + P N ++++ N E GLYL P +KT + I Q T + + NI + + + PV ++ F ++ K + +GGL+ + D VEI+ + +Q PY+ +W+ K ++ +PWA L + +V L S IRNL P+ + +++D++ + L T F R+ D+QI G+MHSGYPI + N + K WG +H++GHN Q T E T N++S+ E + N H +T+ ER+++Y G NW N + AL Y Q++ FGW+ + +VF Y H + + D K+ L+ K S++ NL P +++W WPI TEQELS LP +
Sbjct: 492 MMLHIGKEVYKVTPDPDALLPYIIKDRPNLPTVSNARVRITANTADSEEWISTGLYLCPGMKTYITIPQEIIGTNWQVQLGCQTNNIGGSNVLKRAPVVHERFPLDSEKVQVCNL-WGGLIYFVAPPESKVDGVEIVVQTAVQAPYFKSGETSVADWVGKIRQRPAPWAELEFENLVMTLPSDFIRNLERPDQVAKLWDAIMRSVSDLAATPAKFPRKERFVGDVQISAGFMHSGYPIMML------SSSASELLNVKEAHKHDFWGPLHKLGHNQQRKVWEFPPHTTECTCNLWSVYVHEKVLGVNKAKA-----HPCMTLQSRQERIKEYFSGGKDFENW--NTWTALETYMQLQEKFGWDAFKKVFSLY----HDMKDVPNDNAGKMNLYAKTFSKVVNHNLSPFFKVWGWPIQPNTEQELSHLPAW 903
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Zebrafish
Match: si:ch211-210b2.2 (si:ch211-210b2.2 [Source:ZFIN;Acc:ZDB-GENE-131118-33]) HSP 1 Score: 147.517 bits (371), Expect = 1.398e-35 Identity = 115/398 (28.89%), Postives = 184/398 (46.23%), Query Frame = 2
Query: 1889 VNIKMKLNLLYKYEVAPLGLYLYPRLKT----PVKIIQSKSTRCYIYVNHHHFNIADKSEVTKWPVTYKYFTIERGKWETIQFPFGGLMSISCNENN--DKVEIIFKNVIQIPYYDRRNKD--EWIQK-QKIESPWAVLAGDAVVFILASTAIRNLADPETILQMYDSMFKEEFHLRGTSFPFSRRGIVSSDIQIGVGYMHSGYPIGTQIYHNNNPYKSGYFFNKEILKKDGAWGLMHEMGHNLQXXX-XXXXXXXXXXXXIFSIIATESMTNQNSWSQTSGWFHERLTIER----VQKYLISGTFDNNWRENHFVALCIYAQIKNYFGWEFYAQVFRRYNALTHKQRSISEDE--KIQLWIKITSEISGMNLCPLYELWKWPITNQTEQELSKLPMF 3034
+++ N E GLYL P +KT P +II T+ + + NI + + + PV ++ F ++ K + +GGL+ + D VEI+ + +Q PY+ +W+ K ++ +PWA L + +V L S IRNL P+ + +++D++ + L T F R+ D+QI G+MHSGYPI + N + K WG +HE+GHN Q T E T N++S+ E + N H +T+E ++KY G NW + AL Y Q++ FGW+ + +VF Y H + + D K+ L+ K S++ NL P +++W WPI TEQELS LP +
Sbjct: 523 ARVRITANTADSEEWISTGLYLSPGMKTYITIPPEII---GTKWQVQLGCQTDNIGGSNVLKRAPVVHERFPLDSEKVQVCNL-WGGLIYFVAPPESKVDGVEIVVQTAVQAPYFKSGETSVADWVGKIRQRPAPWAELEFENLVMTLPSDFIRNLERPDEVAKLWDAIMRSVSDLAATPAKFRRKERFVGDVQISAGFMHSGYPIMML------SSSASQLLNVKEAHKHDFWGPLHELGHNQQRKVWEFPPHTTECTCNLWSVYVHEKVLGVNKAKA-----HPCMTLESRQACIKKYFSGGKDLKNWTKA--TALETYMQLQEKFGWDAFKKVFSLY----HDMKDVPNDNAGKMNLYAKTFSKVVNHNLSPFFKVWGWPIQPNTEQELSHLPAW 899
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Zebrafish
Match: si:ch211-210b2.4 (si:ch211-210b2.4 [Source:ZFIN;Acc:ZDB-GENE-131122-12]) HSP 1 Score: 143.28 bits (360), Expect = 3.199e-34 Identity = 119/419 (28.40%), Postives = 190/419 (45.35%), Query Frame = 2
Query: 1826 DLIPPALSLYPGKFQSTNPPFVNIKMKLNLLYKYEVAPLGLYLYPRLKT----PVKIIQSKSTRCYIYVNHHHFNIADKSEVTKWPVTYKYFTIERGKWETIQFPFGGLMSISCNENN--DKVEIIFKNVIQIPYYDRRNKD--EWIQK-QKIESPWAVLAGDAVVFILASTAIRNLADPETILQMYDSMFKEEFHLRGTSFPFSRRGIVSSDIQIGVGYMHSGYPIGTQIYHNNNPYKSGYFFNKEILKKDGAWGLMHEMGHNLQXXX-XXXXXXXXXXXXIFSIIATESMTNQNSWSQTSGWFHERLTIER----VQKYLISGTFDNNWRENHFVALCIYAQIKNYFGWEFYAQVFRRYNALTHKQRSISEDE--KIQLWIKITSEISGMNLCPLYELWKWPITNQTEQELSKLPMF 3034
DL+P + P +N +++ N E GLYL P +KT P +II+ K + + +I + + PV ++ F ++ K + +GGL+ + D VEI+ + +Q PY+ +W+ K ++ +PWA L + +V L S IRNL P+ + +++D++ + L T F R+ D+QI G+MHSGYPI + N + K WG +HE+GHN Q T E T N++S+ E + N H +T+E ++KY G NW + AL Y Q++ FGW+ + +VF Y H + + D K+ L+ K S++ NL P ++ W WPI TEQELS LP +
Sbjct: 509 DLLPYIIKDRPNLPTVSN---ARVRITANTAGCEEWISTGLYLSPGMKTYITIPPEIIEKK---WQVQLGCQTDDIGRLKILKRAPVVHEQFPLDSEKVQVCNL-WGGLIYFVAPPKSKVDGVEIVVQTAVQAPYFKSGETSVADWVGKIRQRPAPWAELEFENLVMTLPSDLIRNLERPDEVAELWDAIMRSVSDLAATPAKFPRKERFVGDVQISAGFMHSGYPIMML------SSSASQLLNVKEAHKHDFWGPLHELGHNQQRKVWEFPPHTTECTCNLWSVYVHEKVLGVNRAKA-----HPCMTLESRQACIKKYFSGGKDLKNWTKA--TALETYMQLQEKFGWDAFKKVFSLY----HDMKDVPNDNAGKMNLYAKTFSKVVNHNLSPFFKTWGWPIQPNTEQELSHLPAW 903
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Zebrafish
Match: zgc:162193 (zgc:162193 [Source:NCBI gene;Acc:323315]) HSP 1 Score: 129.028 bits (323), Expect = 8.245e-30 Identity = 112/423 (26.48%), Postives = 187/423 (44.21%), Query Frame = 2
Query: 1835 PPALSLYPGKFQSTNPPFVNIKMKL--NLLYKYEVAPLGLYLYPRLKTPVKIIQSKSTRCY-IYVNHHHFNIADKSEVTKWPVTYKYFTIERGKWETIQF--PFGGLMSISCNENN--DKVEIIFKNVIQIPYYDRRNKD--EWIQK-QKIESPWAVLAGDAVVFILASTAIRNLADPETILQMYDSMFKEEFHLRGTSFPFSRRGIVSSDIQIGVGYMHSGYPIGTQIYHNNNPYKSGYFFNKEILKKDGAWGLMHEMGHNLQXXXXXXXXXXXXXXXIFSIIATESMTN-------QNSWSQTSGWFHERLTI----ERVQKYLISGTFDNNWRENHFVALCIYAQIKNYFGWEFYAQVFRRYNALTHKQRSISEDE--KIQLWIKITSEISGMNLCPLYELWKWPITNQTEQELSKLPMF 3034
P AL Y K + P N ++++ N E GLYL P +KT + + + + + + NI + + + PV + F ++ E +Q +GGL+ + D VEI+ + +Q PY+ +W+ ++ +PWA L + ++ S IRNL P+ + +++D++ + L R+ +D+QI G+MH+GYPI ++ + P N E K G WG +HE+GHN Q G + F TE N + + S H +T R + Y G N+W ++AL Y Q++ FGW+ + +VF Y H + D K+ L+ + S++ +NL P ++ W WPI TEQ LS LP +
Sbjct: 507 PDALLPYIIKDRPNLPTLSNARVRITANTGGCEEWISTGLYLSPGMKTYIAVPPEIVGKNWQVQLGCQTDNIGGSNTLKRAPVVHARFPLDS---EMVQVWNLWGGLIYLIAPSQTKVDGVEIVVQTAVQAPYFKSGETSVADWVSHIRQAPAPWAELEFENLIMTFDSAFIRNLDRPDEVAKLWDTIMRTITDLAARPPKLPRKERFVADVQISYGFMHAGYPI--MMHSGSAP----GLVNVEEAYKCGLWGAIHELGHNQQRGVWE-----------FPPHTTECTCNLWSLYVHEQVFGIKSANAHPAITPADRQARTKMYFDGGKDLNSW--CMWMALETYMQLQEKFGWDAFKKVFSLY----HDMTGVPNDNAGKMNLYAQTFSKVVNLNLSPFFKAWGWPIQPNTEQNLSHLPAW 903
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Zebrafish
Match: zgc:162193 (zgc:162193 [Source:NCBI gene;Acc:323315]) HSP 1 Score: 129.028 bits (323), Expect = 8.245e-30 Identity = 112/423 (26.48%), Postives = 187/423 (44.21%), Query Frame = 2
Query: 1835 PPALSLYPGKFQSTNPPFVNIKMKL--NLLYKYEVAPLGLYLYPRLKTPVKIIQSKSTRCY-IYVNHHHFNIADKSEVTKWPVTYKYFTIERGKWETIQF--PFGGLMSISCNENN--DKVEIIFKNVIQIPYYDRRNKD--EWIQK-QKIESPWAVLAGDAVVFILASTAIRNLADPETILQMYDSMFKEEFHLRGTSFPFSRRGIVSSDIQIGVGYMHSGYPIGTQIYHNNNPYKSGYFFNKEILKKDGAWGLMHEMGHNLQXXXXXXXXXXXXXXXIFSIIATESMTN-------QNSWSQTSGWFHERLTI----ERVQKYLISGTFDNNWRENHFVALCIYAQIKNYFGWEFYAQVFRRYNALTHKQRSISEDE--KIQLWIKITSEISGMNLCPLYELWKWPITNQTEQELSKLPMF 3034
P AL Y K + P N ++++ N E GLYL P +KT + + + + + + NI + + + PV + F ++ E +Q +GGL+ + D VEI+ + +Q PY+ +W+ ++ +PWA L + ++ S IRNL P+ + +++D++ + L R+ +D+QI G+MH+GYPI ++ + P N E K G WG +HE+GHN Q G + F TE N + + S H +T R + Y G N+W ++AL Y Q++ FGW+ + +VF Y H + D K+ L+ + S++ +NL P ++ W WPI TEQ LS LP +
Sbjct: 507 PDALLPYIIKDRPNLPTLSNARVRITANTGGCEEWISTGLYLSPGMKTYIAVPPEIVGKNWQVQLGCQTDNIGGSNTLKRAPVVHARFPLDS---EMVQVWNLWGGLIYLIAPSQTKVDGVEIVVQTAVQAPYFKSGETSVADWVSHIRQAPAPWAELEFENLIMTFDSAFIRNLDRPDEVAKLWDTIMRTITDLAARPPKLPRKERFVADVQISYGFMHAGYPI--MMHSGSAP----GLVNVEEAYKCGLWGAIHELGHNQQRGVWE-----------FPPHTTECTCNLWSLYVHEQVFGIKSANAHPAITPADRQARTKMYFDGGKDLNSW--CMWMALETYMQLQEKFGWDAFKKVFSLY----HDMTGVPNDNAGKMNLYAQTFSKVVNLNLSPFFKAWGWPIQPNTEQNLSHLPAW 903
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000045101.1 (TRPM8 channel-associated factor 2 [Source:NCBI gene;Acc:100170200]) HSP 1 Score: 153.295 bits (386), Expect = 3.240e-37 Identity = 111/377 (29.44%), Postives = 181/377 (48.01%), Query Frame = 2
Query: 1943 GLYLYPRLKTPVKIIQSKSTR--CYIYVNHHHFNIADKSEVTKWPVTYKYFTIERGKWETIQFPFGGLMSISCNE--NNDKVEIIFKNVIQIPYY--DRRNKDEWIQK-QKIESPWAVLAGDAVVFILASTAIRNLADPETILQMYDSMFKEEFHLRGTSFPFSRRGIVSSDIQIGVGYMHSGYPIGTQIYHNNNPYKSGYFFNKEILKKDGAWGLMHEMGHNLQXXX-XXXXXXXXXXXXIFSIIATESMTNQNSWSQTSGWFHERLTIERVQKYLISGTFDNNWRENHFVALCIYAQIKNYFGWEFYAQVFRRYNALTHKQRSISED--EKIQLWIKITSEISGMNLCPLYELWKWPITNQTEQELSKLPMFLPD 3043
GLYL P+ KT V + + + + + V H ++ K E + P+ + ++ R K + + +GGL+ I E N + + P Y + + D W+Q + + PWA L + ++ + S AIR+L DPE +L +D M L FSR + +D+QI G+MH+GYP+ + Y N ++K+G WG +HE+GHN Q+ T E T N++S+ E++ + + ++ YL +G NW N + AL Y Q++ FGWE + Q+F+ Y +++ IS D K+ LW + SE NL P +E W WPI +T +LS LP++ D
Sbjct: 533 GLYLSPK-KTAVLVFPASAVQQGLQVQVGCHSDDLGSKDEFYRAPIVVRKISVHREKVQVSCY-WGGLLYIIVKERSNLGTIPVQVYGAEPAPTYIKGKTSLDSWLQSLRDLPPPWAELITENIILTVPSDAIRSLNDPEELLGFWDRMMVAITELAAIPTTFSRPERIVADVQISAGWMHAGYPVMVHLASVK------YLTNLSCMQKEGLWGPIHELGHNQQQKVWEFPPHTTEATCNLWSVFVNETVVGVPR-DKANSALEPASRAACIEAYLKTGPKLENW--NVWTALETYLQLQEGFGWEPFKQLFKDYQSMS----GISNDNKSKMNLWAEKFSEAVQTNLIPFFEAWGWPIEEETRSKLSALPVWEKD 894
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000045059.1 (TRPM8 channel-associated factor 2 [Source:NCBI gene;Acc:100170200]) HSP 1 Score: 140.969 bits (354), Expect = 1.971e-33 Identity = 107/379 (28.23%), Postives = 180/379 (47.49%), Query Frame = 2
Query: 1943 GLYLYPR----LKTPVKIIQSKSTRCYIYVNHHHFNIADKSEVTKWPVTYKYFTIERGKWETIQFPFGGLMSI--SCNENNDKVEIIFKNVIQIPYY--DRRNKDEWIQKQK-IESPWAVLAGDAVVFILASTAIRNLADPETILQMYDSMFKEEFHLRGTSFPFSRRGIVSSDIQIGVGYMHSGYPIGTQIYHNNNPYKSGYFFNKEILKKDGAWGLMHEMGHNLQXXX-XXXXXXXXXXXXIFSIIATESMTNQNSWSQTSGWFHERLTIERVQKYLISGTFDNNWRENHFVALCIYAQIKNYFGWEFYAQVFRRYNALTHKQRSISED--EKIQLWIKITSEISGMNLCPLYELWKWPITNQTEQELSKLPMFLPD 3043
GLYL PR L+ P ++Q + V +++ + + PV + ++R K F +GGL+ I N N + + P Y + N D W+Q + + +PWA L + ++ + S AIR+L+DPE +L ++D + L F R +D+QI G+MH+GYPI + + + +++ G WG +HE+GHN Q+ T E T N++S+ E++ ++ G +Q+Y+ +G+ W + + AL Y Q++ FGWE + Q+F+ Y +++ IS D K+ LW + SE NL P +E W WPI +T +LS LP++ D
Sbjct: 533 GLYLAPRKTAVLEFPASVVQQG---LKVQVGCQADDLSSAEKYCRAPVVVRKCHVDRQKVSVSCF-WGGLLYIIVKANSNLGIIPVKVYGAEPAPVYIKGKTNLDSWLQSVRYLPAPWAELITENIILTVPSDAIRSLSDPEALLSLWDKIMVSITELAAIPKTFPRPERFVADVQISAGWMHAGYPIMCHL------ESAKELTDLNVMQTVGIWGPIHELGHNQQKINWEFPPHTTEATCNLWSVYVHETVLGIPR-NKAHGSLQPETRACYIQEYVKNGSNLEQW--DVWTALETYLQLQEGFGWEPFKQLFKDYQSMS----GISNDNKSKMNLWAEKFSEAVQTNLIPFFEAWGWPIEEETRSKLSALPVWEKD 894
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000045084.1 (TRPM8 channel-associated factor 2 [Source:NCBI gene;Acc:100170200]) HSP 1 Score: 137.117 bits (344), Expect = 3.365e-32 Identity = 106/379 (27.97%), Postives = 179/379 (47.23%), Query Frame = 2
Query: 1943 GLYLYPR----LKTPVKIIQSKSTRCYIYVNHHHFNIADKSEVTKWPVTYKYFTIERGKWETIQFPFGGLMSI--SCNENNDKVEIIFKNVIQIPYY--DRRNKDEWIQKQK-IESPWAVLAGDAVVFILASTAIRNLADPETILQMYDSMFKEEFHLRGTSFPFSRRGIVSSDIQIGVGYMHSGYPIGTQIYHNNNPYKSGYFFNKEILKKDGAWGLMHEMGHNLQXXX-XXXXXXXXXXXXIFSIIATESMTNQNSWSQTSGWFHERLTIERVQKYLISGTFDNNWRENHFVALCIYAQIKNYFGWEFYAQVFRRYNALTHKQRSISED--EKIQLWIKITSEISGMNLCPLYELWKWPITNQTEQELSKLPMFLPD 3043
GLYL PR L+ P ++Q + V +++ + + PV + ++R K F +GGL+ I N N + + P Y + N D W+Q + + +PWA L + ++ + S AIR+L+DPE +L ++D + L F R +D+QI G+MH+GYPI + + + +++ G WG +HE+GHN Q+ T E T N++S+ E++ ++ G +Q+Y+ +G+ W + + AL Y Q++ FGWE + ++F+ Y +++ IS D K+ LW + SE NL P +E W WPI T +LS LP++ D
Sbjct: 533 GLYLAPRKTAVLEFPASVVQQG---LKVQVGCQADDLSSAEKYCRAPVVVRKCHVDRQKVSVSCF-WGGLLYIIVKANSNLGIIPVKVYGAEPAPVYIKGKTNLDSWLQSVRYLPAPWAELITENIILTVPSDAIRSLSDPEALLSLWDKIMVSITELAAIPKTFPRPERFVADVQISAGWMHAGYPIMCHL------ESAKELTDLNVMQTVGIWGPIHELGHNQQKINWEFPPHTTEATCNLWSVYVHETVLGIPR-NKAHGSLQPETRACYIQEYVKNGSNLEQW--DVWTALETYLQLQEGFGWEPFKRLFKDYQSMS----GISNDNKSKMNLWAEKFSEAVQTNLIPFFEAWGWPIEEATRIKLSALPVWEKD 894
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000045039.1 (TRPM8 channel-associated factor 2 [Source:NCBI gene;Acc:100170200]) HSP 1 Score: 136.346 bits (342), Expect = 5.651e-32 Identity = 106/379 (27.97%), Postives = 179/379 (47.23%), Query Frame = 2
Query: 1943 GLYLYPR----LKTPVKIIQSKSTRCYIYVNHHHFNIADKSEVTKWPVTYKYFTIERGKWETIQFPFGGLMSI--SCNENNDKVEIIFKNVIQIPYY--DRRNKDEWIQKQK-IESPWAVLAGDAVVFILASTAIRNLADPETILQMYDSMFKEEFHLRGTSFPFSRRGIVSSDIQIGVGYMHSGYPIGTQIYHNNNPYKSGYFFNKEILKKDGAWGLMHEMGHNLQXXX-XXXXXXXXXXXXIFSIIATESMTNQNSWSQTSGWFHERLTIERVQKYLISGTFDNNWRENHFVALCIYAQIKNYFGWEFYAQVFRRYNALTHKQRSISED--EKIQLWIKITSEISGMNLCPLYELWKWPITNQTEQELSKLPMFLPD 3043
GLYL PR L+ P ++Q + V +++ + + PV + ++R K F +GGL+ I N N + + P Y + N D W+Q + + +PWA L + ++ + S AIR+L+DPE +L ++D + L F R +D+QI G+MH+GYPI + + + +++ G WG +HE+GHN Q+ T E T N++S+ E++ ++ G +Q+Y+ +G+ W + + AL Y Q++ FGWE + ++F+ Y +++ IS D K+ LW + SE NL P +E W WPI T +LS LP++ D
Sbjct: 533 GLYLAPRKTAVLEFPASVVQQG---LKVQVGCQADDLSSAEKYCRAPVVVRKCHVDRQKVSVSCF-WGGLLYIIVKANSNLGIIPVKVYGAEPAPVYIKGKTNLDSWLQSVRYLPAPWAELITENIILTVPSDAIRSLSDPEALLSLWDKIMVSITELAAIPKTFPRPERFVADVQISAGWMHAGYPIMCHL------ESAKELTDLNVMQTVGIWGPIHELGHNQQKINWEFPPHTTEATCNLWSVYVHETVLGIPR-NKAHGSLQPETRACYIQEYVKNGSNLEQW--DVWTALETYLQLQEGFGWEPFKRLFKDYQSMS----GISNDNKSKMNLWAEKFSEAVQTNLIPFFEAWGWPIEEATRIKLSVLPVWEKD 894
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000002244.1 (TRPM8 channel-associated factor homolog [Source:NCBI gene;Acc:100489234]) HSP 1 Score: 130.183 bits (326), Expect = 4.577e-30 Identity = 98/374 (26.20%), Postives = 173/374 (46.26%), Query Frame = 2
Query: 1943 GLYLYPRLKTPVKIIQSKSTRCY-IYVNHHHFNIADKSEVTKWPVTYKYFTIERGKWETIQFPFGGLMSI--SCNENNDKVEIIFKNVIQIPYY--DRRNKDEWIQK-QKIESPWAVLAGDAVVFILASTAIRNLADPETILQMYDSMFKEEFHLRGTSFPFSRRGIVSSDIQIGVGYMHSGYPIGTQIYHNNNPYKSGYFFNKEILKKDGAWGLMHEMGHNLQXXX-XXXXXXXXXXXXIFSIIATESMTNQNSWSQTSGWFHERLTIERVQKYLISGTFDNNWRENHFVALCIYAQIKNYFGWEFYAQVFRRYNALTHKQRSISEDEKIQLWIKITSEISGMNLCPLYELWKWPITNQTEQELSKLPMFLPD 3043
GLYL PR ++ S + + + V H + + K + + PV + ++R K F +GGL+ I N N V + P Y + + D W+ +++ +PWA L + ++ + S A+R+L +PE +L ++D + L F R + +D+QI G+MH+GYPI + + + ++K+G WG +HE+GHN Q+ T E T N++++ E++ + G + R++ YL +G W + + AL Y Q++ GW+ + +++R + S K+ LW + S + NL P +E W WPI T +LS LP++ D
Sbjct: 511 GLYLPPRKAVVIEFPASAVQQGFQVQVGCHSDDPSAKETLNRAPVVVRRIHVDRQKVPVSSF-WGGLLYIIVRSNSNFGTVPVRVYGAEPAPIYIKGKTSLDSWLHSIRQLPAPWAELVTENIILTVPSDAVRSLKNPEALLSLWDRIMAAIADLAAKPKKFPRPERIVADVQISAGWMHAGYPIMCDL------ESAKELTDLHHMEKEGIWGPIHELGHNQQKTQWEFPPHTTEATCNLWAVYVHETVLGIPR-DRAHGNLQPNVRTSRIKSYLQNGANLEQW--DGWTALETYLQLQEGLGWDPFRRLYRDPSI---SGMSNENTFKMNLWAEKFSRAAQTNLVPFFEAWGWPIDQSTRSKLSALPVWEKD 871
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Mouse
Match: Tcaf1 (TRPM8 channel-associated factor 1 [Source:MGI Symbol;Acc:MGI:1914665]) HSP 1 Score: 148.673 bits (374), Expect = 6.739e-36 Identity = 117/422 (27.73%), Postives = 204/422 (48.34%), Query Frame = 2
Query: 1808 LSEIGKDL---IPPALSLYPGKF--QSTNPPFVNIKMKLNLLYKYEVAPLGLYLYPRLKTPVKIIQSK-STRCYIYVNHHHFNIADKSEVTKWPVTYKYFTIERGKWETIQFPFGGLMSISCNENN--DKVEIIFKNVIQIPYY--DRRNKDEWIQKQKIE--SPWAVLAGDAVVFILASTAIRNLADPETILQMYDSMFKEEFHLRGTSFPFSRRGIVSSDIQIGVGYMHSGYPIGTQIYHNNNPYKSGYFFNKEILKKDGAWGLMHEMGHNLQXXX-XXXXXXXXXXXXIFSIIATESMTN-QNSWSQTSGWFHERLTIERVQKYLISGTFDNNWRENHFVALCIYAQIKNYFGWEFYAQVFRRYNALTHKQRSISED-EKIQLWIKITSEISGMNLCPLYELWKWPITNQTEQELSKLP 3028
L+ G DL IP +Y ++ S +P VN+ N +Y GLY+ R V + +S S I + H ++ S++ + P+ +++ ++I +GGL+ I +N+ V + K ++ P+Y +K+EW +++ +E PW LA D ++ + + +R L +PE +L+++D M + L G +FP + +D+QI VG+MH+GYPI + N+++++ G WG +HE+G N Q T E T N++ + E++ S + + W R +RV+ YL G +W N + AL Y Q++ FGWE + ++F Y T S++ +K+ LW+K+ S+ NL P +E W WPI + L+ LP
Sbjct: 499 LAHSGSDLSLLIPEIEDVYSSRYLRPSASPITVNVNCT-NPGTRYCWMSTGLYIPGRQVIDVSVPESAASADLKIQIGCHTDDLTRASKLFRGPLVINRCCLDKPT-KSITCLWGGLLYIIVPQNSKLGSVPLTVKGAVRAPFYKLGETSKEEW-KRRLLEYPGPWGELATDNIILTVPTANLRTLENPEPLLRLWDEMMQAVAKLGGETFPLRLPQRIVADVQISVGWMHAGYPIMCHLESVQE------LINEKLIRTKGLWGPVHELGRNQQRQEWEFPPHTTEATCNLWCVYVHETVLGIPRSRANIALWPPVRE--KRVRIYLSKGPSVKHW--NAWTALETYLQLQEAFGWEPFIRLFTEYRNQTTSSSPPSDNVDKMNLWVKMFSQQVQRNLAPFFEAWGWPIQKEVATSLAYLP 907
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Mouse
Match: Tcaf1 (TRPM8 channel-associated factor 1 [Source:MGI Symbol;Acc:MGI:1914665]) HSP 1 Score: 148.673 bits (374), Expect = 6.739e-36 Identity = 117/422 (27.73%), Postives = 204/422 (48.34%), Query Frame = 2
Query: 1808 LSEIGKDL---IPPALSLYPGKF--QSTNPPFVNIKMKLNLLYKYEVAPLGLYLYPRLKTPVKIIQSK-STRCYIYVNHHHFNIADKSEVTKWPVTYKYFTIERGKWETIQFPFGGLMSISCNENN--DKVEIIFKNVIQIPYY--DRRNKDEWIQKQKIE--SPWAVLAGDAVVFILASTAIRNLADPETILQMYDSMFKEEFHLRGTSFPFSRRGIVSSDIQIGVGYMHSGYPIGTQIYHNNNPYKSGYFFNKEILKKDGAWGLMHEMGHNLQXXX-XXXXXXXXXXXXIFSIIATESMTN-QNSWSQTSGWFHERLTIERVQKYLISGTFDNNWRENHFVALCIYAQIKNYFGWEFYAQVFRRYNALTHKQRSISED-EKIQLWIKITSEISGMNLCPLYELWKWPITNQTEQELSKLP 3028
L+ G DL IP +Y ++ S +P VN+ N +Y GLY+ R V + +S S I + H ++ S++ + P+ +++ ++I +GGL+ I +N+ V + K ++ P+Y +K+EW +++ +E PW LA D ++ + + +R L +PE +L+++D M + L G +FP + +D+QI VG+MH+GYPI + N+++++ G WG +HE+G N Q T E T N++ + E++ S + + W R +RV+ YL G +W N + AL Y Q++ FGWE + ++F Y T S++ +K+ LW+K+ S+ NL P +E W WPI + L+ LP
Sbjct: 499 LAHSGSDLSLLIPEIEDVYSSRYLRPSASPITVNVNCT-NPGTRYCWMSTGLYIPGRQVIDVSVPESAASADLKIQIGCHTDDLTRASKLFRGPLVINRCCLDKPT-KSITCLWGGLLYIIVPQNSKLGSVPLTVKGAVRAPFYKLGETSKEEW-KRRLLEYPGPWGELATDNIILTVPTANLRTLENPEPLLRLWDEMMQAVAKLGGETFPLRLPQRIVADVQISVGWMHAGYPIMCHLESVQE------LINEKLIRTKGLWGPVHELGRNQQRQEWEFPPHTTEATCNLWCVYVHETVLGIPRSRANIALWPPVRE--KRVRIYLSKGPSVKHW--NAWTALETYLQLQEAFGWEPFIRLFTEYRNQTTSSSPPSDNVDKMNLWVKMFSQQVQRNLAPFFEAWGWPIQKEVATSLAYLP 907
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Mouse
Match: Tcaf1 (TRPM8 channel-associated factor 1 [Source:MGI Symbol;Acc:MGI:1914665]) HSP 1 Score: 148.673 bits (374), Expect = 6.739e-36 Identity = 117/422 (27.73%), Postives = 204/422 (48.34%), Query Frame = 2
Query: 1808 LSEIGKDL---IPPALSLYPGKF--QSTNPPFVNIKMKLNLLYKYEVAPLGLYLYPRLKTPVKIIQSK-STRCYIYVNHHHFNIADKSEVTKWPVTYKYFTIERGKWETIQFPFGGLMSISCNENN--DKVEIIFKNVIQIPYY--DRRNKDEWIQKQKIE--SPWAVLAGDAVVFILASTAIRNLADPETILQMYDSMFKEEFHLRGTSFPFSRRGIVSSDIQIGVGYMHSGYPIGTQIYHNNNPYKSGYFFNKEILKKDGAWGLMHEMGHNLQXXX-XXXXXXXXXXXXIFSIIATESMTN-QNSWSQTSGWFHERLTIERVQKYLISGTFDNNWRENHFVALCIYAQIKNYFGWEFYAQVFRRYNALTHKQRSISED-EKIQLWIKITSEISGMNLCPLYELWKWPITNQTEQELSKLP 3028
L+ G DL IP +Y ++ S +P VN+ N +Y GLY+ R V + +S S I + H ++ S++ + P+ +++ ++I +GGL+ I +N+ V + K ++ P+Y +K+EW +++ +E PW LA D ++ + + +R L +PE +L+++D M + L G +FP + +D+QI VG+MH+GYPI + N+++++ G WG +HE+G N Q T E T N++ + E++ S + + W R +RV+ YL G +W N + AL Y Q++ FGWE + ++F Y T S++ +K+ LW+K+ S+ NL P +E W WPI + L+ LP
Sbjct: 499 LAHSGSDLSLLIPEIEDVYSSRYLRPSASPITVNVNCT-NPGTRYCWMSTGLYIPGRQVIDVSVPESAASADLKIQIGCHTDDLTRASKLFRGPLVINRCCLDKPT-KSITCLWGGLLYIIVPQNSKLGSVPLTVKGAVRAPFYKLGETSKEEW-KRRLLEYPGPWGELATDNIILTVPTANLRTLENPEPLLRLWDEMMQAVAKLGGETFPLRLPQRIVADVQISVGWMHAGYPIMCHLESVQE------LINEKLIRTKGLWGPVHELGRNQQRQEWEFPPHTTEATCNLWCVYVHETVLGIPRSRANIALWPPVRE--KRVRIYLSKGPSVKHW--NAWTALETYLQLQEAFGWEPFIRLFTEYRNQTTSSSPPSDNVDKMNLWVKMFSQQVQRNLAPFFEAWGWPIQKEVATSLAYLP 907
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Mouse
Match: Tcaf3 (TRPM8 channel-associated factor 3 [Source:MGI Symbol;Acc:MGI:3042585]) HSP 1 Score: 141.354 bits (355), Expect = 1.362e-33 Identity = 109/373 (29.22%), Postives = 177/373 (47.45%), Query Frame = 2
Query: 1943 GLYLYPRLKTPVKIIQSKST--RCYIYVNHHHFNIADKSEVTKWPV-TYKYFTIERGKWETIQFPFGGLMSISCNE--NNDKVEIIFKNVIQIPYY--DRRNKDEW---IQKQKIESPWAVLAGDAVVFILASTAIRNLADPETILQMYDSMFKEEFHLRGTSFPFSRRGIVSSDIQIGVGYMHSGYPIGTQIYHNNNPYKSGYFFNKEILKKDGAWGLMHEMGHNLQXXX-XXXXXXXXXXXXIFSIIATESMTNQNSWSQTSGWFHERLTIERVQKYLISGTFDNNWRENHFVALCIYAQIKNYFGWEFYAQVFRRYNALTHKQRSISEDEKIQLWIKITSEISGMNLCPLYELWKWPITNQTEQELSKLP 3028
GLYL P + ++ S++T + + + H NI+ + PV TY Y +I + +GGL+ I N D V + + + PY+ + ++EW I K +PW LA D ++ + + ++ L DP +LQ++D M + L FPF R V D QI G++HSGYPI I ++ ++ G WG++HE+GHN Q+ T E N+++I E++ N Q + L +R++ +L G +NW + AL Y Q++ FGWE + QVF Y L+ + + ++K+ LW+K SE NL P +E W WP+ + L+ LP
Sbjct: 539 GLYL-PEGQVAQVLLPSEATHAKLKVLIGCHRDNISQARTYFRPPVMTYVYHLTSSQT--SISWLYGGLLYIMVPNKYNQDNVSVTIRGAVSAPYFRLGKTTQEEWKNLITHSK--APWGELATDNIILTIPTVNLKELQDPYPLLQLWDKMVRAVAKLAARPFPFQRAERVVLDKQISFGFLHSGYPIMGLISIVEG------IISEFKIRSHGIWGVIHELGHNHQKSGWTFPPHTTEALCNLWTIYVHETVLNIPR-EQAHPSLNPELRRQRIKYHLNKGAPLSNWI--MWTALETYLQLQEGFGWEPFIQVFADYRTLSGLPQ--NNEDKMNLWVKKFSEAVHKNLAPFFEAWGWPVKYAVAKSLASLP 895
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Mouse
Match: Tcaf2 (TRPM8 channel-associated factor 2 [Source:MGI Symbol;Acc:MGI:2385258]) HSP 1 Score: 135.576 bits (340), Expect = 8.938e-32 Identity = 103/371 (27.76%), Postives = 175/371 (47.17%), Query Frame = 2
Query: 1943 GLYLYPRLKTPVKIIQ-SKSTRCYIYVNHHHFNIADKSEVTKWPVTYKYFTIERGKWETIQFPFGGLMSISCNENN--DKVEIIFKNVIQIPYY--DRRNKDEWIQK-QKIESPWAVLAGDAVVFILASTAIRNLADPETILQMYDSMFKEEFHLRGTSFPFSRRGIVSSDIQIGVGYMHSGYPIGTQIYHNNNPYKSGYFFNKEILKKDGAWGLMHEMGHNLQXXX-XXXXXXXXXXXXIFSIIATESMTNQNSWSQTSGWFHERLTIERVQKYLISGTFDNNWRENHFVALCIYAQIKNYFGWEFYAQVFRRYNALTHKQRSISEDE--KIQLWIKITSEISGMNLCPLYELWKWPITNQTEQELSKLP 3028
GLYL T + + + + S + + H ++ ++ + PV + R + ++ +GGL+ I + V + N + PYY + + +EW QK PW LA D V+ + + +++ L +PE +LQ++D M + L FPF R + +D+Q+ G+MHSGYPI + H + + N ++ G WG +HE+GHN Q T E T N++S+ E++ +Q +R++++L G NW N + AL Y Q++ FGWE + +F Y + + I ED K+ +W+K+ SE NL P +E W WPI ++L+ P
Sbjct: 549 GLYLLEGQSTEISVSEPAASAGLKVQIGCHTDDLTFAIKLFRAPVVTYQCCMNRTQ-RSVSCLWGGLLYIIVPKGCQLGPVSVTITNAVPAPYYKLGKTSLEEWKSCIQKNLGPWGELATDNVILTVPTASLKTLENPEPLLQLWDEMMQAVARLASQPFPFQRPERIVADVQLSAGWMHSGYPI---MCHMESVQELVSLAN---IRSKGLWGPIHELGHNQQCRGWEFPPHTTEATCNLWSVYVHETVLGIPR-AQAHPQLKPEEREKRIKEHLQKGAPLQNW--NVWTALETYLQLQEVFGWEPFITLFAEYQTIFY----IPEDNECKMNIWLKLFSEKVQKNLVPFFEAWGWPIQKDVAEDLACYP 905
BLAST of Peptidase M60 domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8BNE1|TCAF1_MOUSE (TRPM8 channel-associated factor 1 OS=Mus musculus OX=10090 GN=Tcaf1 PE=2 SV=1) HSP 1 Score: 148.673 bits (374), Expect = 4.497e-35 Identity = 117/422 (27.73%), Postives = 204/422 (48.34%), Query Frame = 2
Query: 1808 LSEIGKDL---IPPALSLYPGKF--QSTNPPFVNIKMKLNLLYKYEVAPLGLYLYPRLKTPVKIIQSK-STRCYIYVNHHHFNIADKSEVTKWPVTYKYFTIERGKWETIQFPFGGLMSISCNENN--DKVEIIFKNVIQIPYY--DRRNKDEWIQKQKIE--SPWAVLAGDAVVFILASTAIRNLADPETILQMYDSMFKEEFHLRGTSFPFSRRGIVSSDIQIGVGYMHSGYPIGTQIYHNNNPYKSGYFFNKEILKKDGAWGLMHEMGHNLQXXX-XXXXXXXXXXXXIFSIIATESMTN-QNSWSQTSGWFHERLTIERVQKYLISGTFDNNWRENHFVALCIYAQIKNYFGWEFYAQVFRRYNALTHKQRSISED-EKIQLWIKITSEISGMNLCPLYELWKWPITNQTEQELSKLP 3028
L+ G DL IP +Y ++ S +P VN+ N +Y GLY+ R V + +S S I + H ++ S++ + P+ +++ ++I +GGL+ I +N+ V + K ++ P+Y +K+EW +++ +E PW LA D ++ + + +R L +PE +L+++D M + L G +FP + +D+QI VG+MH+GYPI + N+++++ G WG +HE+G N Q T E T N++ + E++ S + + W R +RV+ YL G +W N + AL Y Q++ FGWE + ++F Y T S++ +K+ LW+K+ S+ NL P +E W WPI + L+ LP
Sbjct: 499 LAHSGSDLSLLIPEIEDVYSSRYLRPSASPITVNVNCT-NPGTRYCWMSTGLYIPGRQVIDVSVPESAASADLKIQIGCHTDDLTRASKLFRGPLVINRCCLDKPT-KSITCLWGGLLYIIVPQNSKLGSVPLTVKGAVRAPFYKLGETSKEEW-KRRLLEYPGPWGELATDNIILTVPTANLRTLENPEPLLRLWDEMMQAVAKLGGETFPLRLPQRIVADVQISVGWMHAGYPIMCHLESVQE------LINEKLIRTKGLWGPVHELGRNQQRQEWEFPPHTTEATCNLWCVYVHETVLGIPRSRANIALWPPVRE--KRVRIYLSKGPSVKHW--NAWTALETYLQLQEAFGWEPFIRLFTEYRNQTTSSSPPSDNVDKMNLWVKMFSQQVQRNLAPFFEAWGWPIQKEVATSLAYLP 907
BLAST of Peptidase M60 domain-containing protein vs. UniProt/SwissProt
Match: sp|A6NFQ2|TCAF2_HUMAN (TRPM8 channel-associated factor 2 OS=Homo sapiens OX=9606 GN=TCAF2 PE=1 SV=2) HSP 1 Score: 147.132 bits (370), Expect = 1.336e-34 Identity = 103/373 (27.61%), Postives = 176/373 (47.18%), Query Frame = 2
Query: 1943 GLYLYPRLKTPVKIIQSK-STRCYIYVNHHHFNIADKSEVTKWPVTYKYFTIERGKWETIQFPFGGLMSISCNENN--DKVEIIFKNVIQIPYY--DRRNKDEW-IQKQKIESPWAVLAGDAVVFILASTAIRNLADPETILQMYDSMFKEEFHLRGTSFPFSRRGIVSSDIQIGVGYMHSGYPIGTQIYHNNNPYKSGYFFNKEILKKDGAWGLMHEMGHNLQXXX-XXXXXXXXXXXXIFSIIATESMTNQNSWSQTSGWFHERLTI----ERVQKYLISGTFDNNWRENHFVALCIYAQIKNYFGWEFYAQVFRRYNALTHKQRSISEDEKIQLWIKITSEISGMNLCPLYELWKWPITNQTEQELSKLP 3028
GLYL V + ++ S + + H ++ ++++ PV ++R + ++ +GGL+ + + + V + + + PYY + + +EW Q Q+ +PW LA D ++ + +T ++ L DPE +L+++D M + L FPF R + +D+QI G+MHSGYPI + N+ ++ G WG +HE+GHN Q T E T N++S+ E++ HE L+ R++ +L G +W N + AL Y Q++ FGWE + Q+F Y L+H + ++ LW+K SE NL P +E W WPI + L+ LP
Sbjct: 548 GLYLLEGQNAEVSLSEAAASAGLRVQIGCHTDDLTKARKLSRAPVVTHQCWMDRTE-RSVSCLWGGLLYVIVPKGSQLGPVPVTIRGAVPAPYYKLGKTSLEEWKRQMQENLAPWGELATDNIILTVPTTNLQALKDPEPVLRLWDEMMQAVARLAAEPFPFRRPERIVADVQISAGWMHSGYPIMCHLESVKE------IINEMDMRSRGVWGPIHELGHNQQRHGWEFPPHTTEATCNLWSVYVHETVLG-----IPRAQAHEALSPPERERRIKAHLGKGAPLCDW--NVWTALETYLQLQEAFGWEPFTQLFAEYQTLSHLPK--DNTGRMNLWVKKFSEKVKKNLVPFFEAWGWPIQKEVADSLASLP 904
BLAST of Peptidase M60 domain-containing protein vs. UniProt/SwissProt
Match: sp|Q6P6V7|TCAF3_RAT (TRPM8 channel-associated factor 3 OS=Rattus norvegicus OX=10116 GN=Tcaf3 PE=2 SV=1) HSP 1 Score: 142.51 bits (358), Expect = 3.872e-33 Identity = 109/373 (29.22%), Postives = 178/373 (47.72%), Query Frame = 2
Query: 1943 GLYLYPRLKTPVKIIQSKST--RCYIYVNHHHFNIADKSEVTKWPV-TYKYFTIERGKWETIQFPFGGLMSISCNE--NNDKVEIIFKNVIQIPYY--DRRNKDEWIQKQKIE---SPWAVLAGDAVVFILASTAIRNLADPETILQMYDSMFKEEFHLRGTSFPFSRRGIVSSDIQIGVGYMHSGYPIGTQIYHNNNPYKSGYFFNKEILKKDGAWGLMHEMGHNLQXXX-XXXXXXXXXXXXIFSIIATESMTNQNSWSQTSGWFHERLTIERVQKYLISGTFDNNWRENHFVALCIYAQIKNYFGWEFYAQVFRRYNALTHKQRSISEDEKIQLWIKITSEISGMNLCPLYELWKWPITNQTEQELSKLP 3028
GLYL P + + +++T + + + H NI+ + PV TY Y +I + +GGL+ I + N D V + + PY+ + ++EW K IE +PW LA D ++ + + ++ L DP +LQ++D + K L FPF R + D QI G++HSGYPI I N+ ++ G WG+ HE+GHN Q+ T E N++SI E++ N Q + L +R++ +L G +NW + AL Y Q++ FGWE + Q+F Y LT + + ++K+ LW+K SE+ NL P ++ W WP+ + + L+ LP
Sbjct: 539 GLYL-PEGQVAQVTLPTEATHAKLKVLIGCHIDNISQAKTYIRPPVMTYVYHLTSSQT--SISWLYGGLLYIMVPDKYNQDNVSVTISGAVSAPYFRLGKTTQEEW--KNLIEHSKAPWGELATDNIILTIPTVNLKVLQDPYPLLQLWDKIVKAVAKLAARPFPFQRPERIVLDKQISFGFLHSGYPIMGLIIIVEG------IINEFKIRSHGVWGVTHELGHNHQKPGWTFRPHTTEALCNLWSIYVHETVLNIPR-DQAHPSLNPELRKQRIKDHLNKGAPLSNWIV--WTALETYLQLQEGFGWEPFIQLFANYQTLTGLPQ--NNEDKMNLWVKKFSEVVQKNLAPFFKAWGWPVQHAVAKSLASLP 895
BLAST of Peptidase M60 domain-containing protein vs. UniProt/SwissProt
Match: sp|Q6QR59|TCAF3_MOUSE (TRPM8 channel-associated factor 3 OS=Mus musculus OX=10090 GN=Tcaf3 PE=1 SV=1) HSP 1 Score: 141.354 bits (355), Expect = 9.525e-33 Identity = 109/373 (29.22%), Postives = 177/373 (47.45%), Query Frame = 2
Query: 1943 GLYLYPRLKTPVKIIQSKST--RCYIYVNHHHFNIADKSEVTKWPV-TYKYFTIERGKWETIQFPFGGLMSISCNE--NNDKVEIIFKNVIQIPYY--DRRNKDEW---IQKQKIESPWAVLAGDAVVFILASTAIRNLADPETILQMYDSMFKEEFHLRGTSFPFSRRGIVSSDIQIGVGYMHSGYPIGTQIYHNNNPYKSGYFFNKEILKKDGAWGLMHEMGHNLQXXX-XXXXXXXXXXXXIFSIIATESMTNQNSWSQTSGWFHERLTIERVQKYLISGTFDNNWRENHFVALCIYAQIKNYFGWEFYAQVFRRYNALTHKQRSISEDEKIQLWIKITSEISGMNLCPLYELWKWPITNQTEQELSKLP 3028
GLYL P + ++ S++T + + + H NI+ + PV TY Y +I + +GGL+ I N D V + + + PY+ + ++EW I K +PW LA D ++ + + ++ L DP +LQ++D M + L FPF R V D QI G++HSGYPI I ++ ++ G WG++HE+GHN Q+ T E N+++I E++ N Q + L +R++ +L G +NW + AL Y Q++ FGWE + QVF Y L+ + + ++K+ LW+K SE NL P +E W WP+ + L+ LP
Sbjct: 539 GLYL-PEGQVAQVLLPSEATHAKLKVLIGCHRDNISQARTYFRPPVMTYVYHLTSSQT--SISWLYGGLLYIMVPNKYNQDNVSVTIRGAVSAPYFRLGKTTQEEWKNLITHSK--APWGELATDNIILTIPTVNLKELQDPYPLLQLWDKMVRAVAKLAARPFPFQRAERVVLDKQISFGFLHSGYPIMGLISIVEG------IISEFKIRSHGIWGVIHELGHNHQKSGWTFPPHTTEALCNLWTIYVHETVLNIPR-EQAHPSLNPELRRQRIKYHLNKGAPLSNWI--MWTALETYLQLQEGFGWEPFIQVFADYRTLSGLPQ--NNEDKMNLWVKKFSEAVHKNLAPFFEAWGWPVKYAVAKSLASLP 895
BLAST of Peptidase M60 domain-containing protein vs. UniProt/SwissProt
Match: sp|Q5XHI4|TCAF_XENLA (TRPM8 channel-associated factor homolog OS=Xenopus laevis OX=8355 GN=tcaf PE=2 SV=1) HSP 1 Score: 139.043 bits (349), Expect = 4.392e-32 Identity = 106/377 (28.12%), Postives = 175/377 (46.42%), Query Frame = 2
Query: 1943 GLYLYPR----LKTPVKIIQSKSTRCYIYVNHHHFNIADKSEVTKWPVTYKYFTIERGKWETIQFPFGGL--MSISCNENNDKVEIIFKNVIQIPYY--DRRNKDEWIQK-QKIESPWAVLAGDAVVFILASTAIRNLADPETILQMYDSMFKEEFHLRGTSFPFSRRGIVSSDIQIGVGYMHSGYPIGTQIYHNNNPYKSGYFFNKEILKKDGAWGLMHEMGHNLQXXX-XXXXXXXXXXXXIFSIIATESMTNQNSWSQTSGWFHERLTIERVQKYLISGTFDNNWRENHFVALCIYAQIKNYFGWEFYAQVFRRYNALTHKQRSISEDEKIQLWIKITSEISGMNLCPLYELWKWPITNQTEQELSKLPMFLPD 3043
GLYL PR L+ P + + + + + ADK + PV + F ++ + F +GGL +++ N N + + P Y + + D WIQ + + +PWA L + ++ + S AIR+L+DPE +L ++D + L R +D+QI G+MH+GYPI + + + I++ G WG +HE+GHN Q+ T E T N++S+ E++ SQ +Q+YL +G+ W N + AL Y Q++ FGWE + Q+F+ Y +++ + K+ LW + SE NL P +E W WPI T +LS LP++ D
Sbjct: 530 GLYLAPRKTAVLEFPASAVH-QGLQVQVGCQSDDLSSADK--YCRAPVVVRRFHVDSQRVSVSCF-WGGLVYITVKANSNLGIIPVKVYEAEPAPIYIKGKTSLDTWIQSIRNLPAPWAELITENIILTVPSDAIRSLSDPEALLSLWDKIMVAITELAAIPKKLPRPERFVADVQISAGWMHAGYPIMCHLE------SAKELTDLNIMQTGGIWGPIHELGHNQQKTNWELPPHTTEATCNLWSVYVHETVLGIPR-SQAHCCLQAETRANHIQEYLRNGSNIEQW--NVWTALETYLQLQEGFGWEPFKQLFKDYQSMSGIRNE--NKSKMNLWAEKFSEAVQTNLVPFFEAWGWPIEEATHSKLSVLPVWEKD 891
BLAST of Peptidase M60 domain-containing protein vs. TrEMBL
Match: V3ZHF7 (Peptidase M60 domain-containing protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_236481 PE=4 SV=1) HSP 1 Score: 220.32 bits (560), Expect = 2.392e-56 Identity = 166/610 (27.21%), Postives = 299/610 (49.02%), Query Frame = 2
Query: 1355 KVLLEYIKSGLRIIIGFESWSY--IDKIKPLLD-------SELKILFYAAGVW--PSLKYVQDQFQPVTQHSIHTMSLDKKFEYAKINNVTMNDVLAAYREVFD-DIYIERSLDKKDFDSMKKVIHDLYTDYWPFIQSLTPCLNYAISKQSDKGFLKFFSYILLSEIGKDLIP-PALSLYPGKFQSTNPPFVNIKMKLNLLYKYEVA---PLGLYLYPRLKTPVKIIQSKSTRC--YIYVNHHHFNIADKSEVTKWPVTYKYFTIERGKWETIQFPFGGLMSISCNENNDKVEIIFKNVIQIPYYDRRNKD---EWIQKQKIESPWAVLAGDAVVFILASTAIRNLADPETILQMYDSMFKEEFHLRGTSFPFSRRGIVSSDIQIGVGYMHSGYPIGTQIYHNNNPYKSGYFFNKEILKKDGAWGLMHEMGHNLQXXXXXXXXXXXXXXXIFSIIATESMTNQNSWSQTSGWFHERLT--IERVQKYLISGTFDNNWRENHFVALCIYAQIKNYFGWEFYAQVFRRYNALTHKQRSISEDEKIQLWIKITSEISGMNLCPLYELWKWPITNQTEQELSKLPMFLPDDFVTKSVEKRIKEIICKRGSIFRQ 3115
K +LEYI++G ++ +W + I K + D E+ I++ W S ++ +QH IH + ++ +++ + ++ D + + +S+ KK + + K+I + P +S K + F + +L++ G P + L+PG F + +PP + + ++ + E+ P G Y+ + ++I+ +S C I + H ++ + + +WP+ + I + + ++ P GGLM + + K+ I KN I+ P +D + W ++ WA L G +VF L + ++ +L DP +L+ +D + HLRGT RR + +D+Q GYMHSGYPI T + +P KS + N + L + G WGL HE+GHN+Q+ T+TF GTGE T NIF++ A + + +Q S W H L + + ++++ S + W+ + +AL +YAQ+ N FGW Y + FR+Y + +E+EKI W + S+ S NL PL +LW P+++ ++L P FLPDD +T+ V ++++E+ K + R+
Sbjct: 139 KEILEYIQNGGALLHAVCAWGWLQIRNTKNIHDIPLYEVLEEVGIIYTKGYFWLPKSGLHIAISKASESQHVIHAL-----------DHTHLDNCCSTLSQINDCPVKVLQSVMKKSGEKVHKIISEKE-------HECIPSEKRPVSSSIGKSVM--FLHDVLAKTGNGYKKMPGIDLFPGDF-TEDPPLSDGR----IIIESEIPAAHPTGFYVRAGEEVELEIVTEESLNCGWEIQIGCHSDHLQTSNAMKRWPIITEKQKITQKNLK-MKTPIGGLMYVWSPKMASKIIINVKNAIESPLFDLTQPETIINWKTNRQAPGLWADLGGHHIVFTLPAKSVGDLEDPTAVLESWDRVVCAHHHLRGTDPNSQRREWIVADVQPSCGYMHSGYPIVTHL-DVADPSKSSFLLNNKTLLESGNWGLFHELGHNMQKPTWTFRGTGEVTCNIFTLHAMDVI------AQKSPWIHSWLEGKVPKARQFIRSSAGFSKWQSDPGIALFVYAQLYNQFGWSVYKKTFRQYEEQDMPPQLKTEEEKIDYWFETMSKFSEYNLAPLADLWSIPLSDTCREQLKVFPSFLPDDEITQGVPEKVEELEKKYPKLVRK 715
BLAST of Peptidase M60 domain-containing protein vs. TrEMBL
Match: R7UHN9 (Peptidase M60 domain-containing protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_195748 PE=4 SV=1) HSP 1 Score: 216.468 bits (550), Expect = 2.774e-55 Identity = 174/629 (27.66%), Postives = 309/629 (49.13%), Query Frame = 2
Query: 1244 LLNKSYLQEIISKNKSQSVLSEPFIWNAEQVFGQDLVKVLLEYIKSGLRIIIGFESWSYIDKIKPLLDSELKI--LFYAAGVWPSLKYVQDQFQPVTQHSIHTMSLDKKFEYAKINNVTMNDVLAAY--REVFDDI--YIERSLDKKDFDSMKKVIHDLYTDYWPFIQSLTPCLNYAISKQSDKGFLKFFSYILLSEIGKDLIPPALSLYPGKFQSTNPPFVNIKMKLNL-LYKYEVAPLGLYLYPRLKTPVKIIQSKST---RCYIYVNHHHFNIADKSEVTKWPVTYKYFTIERGKWET--IQFPFGGLMSISCNENNDKVEIIFKNVIQIPYYDRRNKDEWIQKQKIESPWAVLAGDAVVFILASTAIRNLADPETILQMYDSMFKEEFHLRGTSFPFSRRGIVSSDIQIGVGYMHSGYPIGTQIYHNNNPYKSGYFFNKEILKKDGAWGLMHEMGHNLQXXXXXXXXXXXXXXXIFSIIATESMTNQNSWSQTSGWFHERLTIERVQKYLISGTFDNNWRENHFVALCIYAQIKNYFGWEFYAQVFRRYNALTHKQRSISEDEKIQLWIKITSEISGMNLCPLYELWKWPITNQTEQELSKLPMFLPDDFVTKSVEKRIKEIICK 3094
L N + + EI++K +++SV I Q F + V +LL++I+ G +I W ++ K + ++ + + AG+ + Y+ T SI + + K + + N L AY + +D+ I RS + D +++ TD++ + P Y + KG L LS + P + +PG F+ + +++NL + ++ P +YL P +T I ST + +++ H ++ S+ + P K +R +T I P+GG + + ++++ NV++ P Y D WI ++ WA LAG ++ L S++I++L DP +L +DS+ +R T R+ + D+Q VGYMHSGYPI T + +P + N + LK +G WGL HE+GHN+Q +TF GT E T N+F++ A + + W W + ++ +++YL++G W++ +AL IYAQ+ ++ GW Y VFR+Y ++++Q+ ++DEKI+LWI +E G NLC L+ W + I N ++ L++LP+FLP D +T V +RI +++ +
Sbjct: 97 LKNNASIHEILAK-ETESVAIVRII---GQKFDEIEVLMLLDFIEHGGGLIFAICPWGWLQLNKNYAEEDMPMYSILERAGIHFTGHYINGNADGFTVPSIPSTARVPTL-IQKCLSSSENLGLYAYDLASLLEDLPLRIVRSTFQDLLDEVEE------TDFYNLV---IPEEKYPLKDNRSKGLLLLSC---LSARVRGDKAPGVHAFPGDFEGD---VQHKCVRINLDSARRDIFPAAVYL-PAGETLEIEIHEGSTDPQKWKVWIGAHSDDLVRSSQWKRLP---KVHIKQRLSEDTNVIFSPYGGNVYFESPDEESQLDVTVSNVVESPCY----TDHWIGQRDAPGLWADLAGRHIMITLPSSSIKDLVDPSEVLAFWDSVVAAHHVVRTTDVSSHRKQWIVCDVQPVVGYMHSGYPIVTHM-DVADPTSDQFLLNHDKLKAEGNWGLYHELGHNMQRLEWTFQGTSEVTVNVFTLHAMDVVNGVKPWIHP--WLNNQMN--AIKRYLMAGADFTTWKKEPGIALGIYAQLAHHLGWGTYKAVFRKYEVMSNEQKPKTDDEKIRLWITTFAECCGQNLCALFRFWGFTIPNDLQRNLAELPLFLPMDEMTLFVPERIAKVVAE 692
BLAST of Peptidase M60 domain-containing protein vs. TrEMBL
Match: A0A1S3I0H4 (TRPM8 channel-associated factor 2-like OS=Lingula unguis OX=7574 GN=LOC106159184 PE=4 SV=1) HSP 1 Score: 212.231 bits (539), Expect = 9.293e-54 Identity = 132/439 (30.07%), Postives = 228/439 (51.94%), Query Frame = 2
Query: 1838 PALSLYPGKFQSTNPPFVNIKMKLNLLYKYEVAPLGLYLYPRLKTPVKIIQSKSTRCY---IYVNHHHFNIADKSEV-TKWPVTYKYFTIERGKWET-IQFPFGGLMSISCNENNDKVEIIFKNVIQIPYYDRRNKD---EWIQKQKIESPWAVLAGDAVVFILASTAIRNLADPETILQMYDSMFKEEFHLRGTSFPFSRRGIVSSDIQIGVGYMHSGYPIGTQ--IYHNNNPYKSG--YFFNKEILKKDGAWGLMHEMGHNLQXXXXXXXXXXXXXXXIFSIIATESMTNQNSWSQTSGWFHERLTIERVQKYLISGTFDNNWRENHFVALCIYAQIKNYFGWEFYAQVFRRYNALTHKQRSISEDE--KIQLWIKITSEISGMNLCPLYELWKWPITNQTEQELSKLPMFLPDDFVTKSVEKRIKEIICKRGSIFR 3112
P + ++PG F S+ PP +++ L ++ ++ G Y+ V + + T I + H ++ + E +WP +E K T + P+GGL+ E N ++ +I NV++ P++D + +W +++ WA LAG +VF + ST++R + DP TIL ++DS + LRGT +R V +D Q GYMH+GYPI T + N Y + F++ +K G WGL HE+GHN+Q +TF+G GE T NIF++ E++T ++W+ + ++ E++ + L S ++W+++ F ALC+Y+Q+ + FGW + VFR Y K+ ++D+ KI +W SEI NL P+ + W P++ L+ P FLP+D +T + + R+ +++ I R
Sbjct: 286 PGIGVFPGDF-SSKPPLQTVRLNLTTKHRQRLS-TGYYVPAGQPVKVTVTSDQGTDLSGWKICIGAHDDSLVNVKEPWRRWP---DVAVLEELKATTALSSPYGGLLFFDSPERNAELTVIVCNVVEAPFFDLTKPEIVEDWSRRRNAPGLWAELAGRHIVFTVPSTSVREIDDPTTILALWDSAVAAQHDLRGTDRNLQKRERVVADEQPSAGYMHAGYPIVTHLDVVDPNFQYNGSDNFVFSESGMKSYGNWGLFHEIGHNMQRKAWTFSGMGEVTNNIFTLYTYEAVTGNDAWNNPT---MKKFRAEKLPRLLQSQPSLSDWKKDPFFALCVYSQLAHEFGWRSFKTVFRLYENSVKKEEESNQDDGAKIDMWFGRFSEIVRHNLSPMCDFWGIPLSTGVRNNLTLFPAFLPNDEITAAGQARVDQVLPNYPGIVR 716
BLAST of Peptidase M60 domain-containing protein vs. TrEMBL
Match: V4A0M8 (Peptidase M60 domain-containing protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_165593 PE=4 SV=1) HSP 1 Score: 212.231 bits (539), Expect = 9.087e-53 Identity = 158/603 (26.20%), Postives = 282/603 (46.77%), Query Frame = 2
Query: 1361 LLEYIKSGLRIIIGFESWSYI--DKIKPLLDSELKILFYAAGVWPSLKYVQDQFQPVTQHSIHTMSLDKKFEYAKINNVTMNDVLAAYREVFDDIYIERSL-DKK------DFDSMKKVIHDLYTDYWPFIQSLTPCLNYAISKQSDKGFLKFFSYILLSEIGK-DLIPPALSLYPGKFQSTNPPFVNIKMKLNLLYKYEVAPLGLYLYPRLKTPVKIIQSKSTRCYIYVNHHHFNIADKSEVTKWPVTYKYFTIERGKWETIQFPFGGLMSISCNENNDKVEIIFKNVIQIPYYD---RRNKDEWIQKQKIESPWAVLAGDAVVFILASTAIRNLADPETILQMYDSMFKEEFHLRGTSFPFSRRGIVSSDIQIGVGYMHSGYPIGTQIYHNNNPYKSGYFFNKEILKKDGAWGLMHEMGHNLQXXXXXXXXXXXXXXXIFSIIATESMTNQ----NSWSQTSGWFHERLTIERVQKYLISGTFDNNWRENHFVALCIYAQIKNYFGWEFYAQVFRRYNALTHKQRSISEDEKIQLWIKITSEISGMNLCPLYELWKWPITNQTEQELSKLPMFLPDDFVTKSVEKRIKEIICK-RGSIFRQ 3115
+L ++ SG + W ++ K K D + A G+ + +YV+ P + + ++ + + ++ D A +V + + + L DKK + V+ DY P + + K + L+++GK + I P ++ +PG F+ST P ++ + L+ Y+ +V P G Y+ V ++ + + H ++ +SE+ +WP + + ++ FGGL+ + N + + NVIQ P +D ++W +++ WA + + ++ L S +IRNL P ++++ +D + K FHL+G R+ + +D+Q GYMHSGYP+ T + NP + N L G+WG+ HE GHN+QEG +TF GT E T NIF++ A +++ + + W Q +R Q Y ++W+ + +AL IYAQI ++ GW + +VFRRY + E+++I LW + SE+S +NL L + WK P++++ +E+SK FLPDD V + +R I+ K + RQ
Sbjct: 351 VLNFVISGGAFVHTMCPWGWLMGHKGKSFDDQPFDPVLDAVGIGYTKRYVE---IPADGLDVQSCCSSEQCHLGRAVDASIGDA-RALSQVGESLQLLSELTDKKLHMFSGKLSKLSGVLESTDIDY-------VPSEHCPVKSSEGKALIGLCE--TLNKMGKVNQILPGIANFPGDFEST-PSKTSVTLTLSS-YQEDVHPTGYYVQAGDSLAVSVLSQNGKGWTVQIGAHSDCLSGQSELKRWPNVVCCKPLNE-QCTIVKATFGGLVYFTSPSNQQSITVQLDNVIQAPLFDLTLPTTIEQWNGRRQAPGLWADICSEFLIITLPSKSIRNLDGPVSVMKKWDEVLKAHFHLKGIDIRNHRKQWLVTDVQPSAGYMHSGYPVVTHL-DVANPSHEFFLLNSHNLNTKGSWGVFHEFGHNMQEGVWTFPGTTEVTVNIFTLHAMDTLIGKRPIVHEWLQNQMSNAKRYLYHNDQNY-------SHWKSDPGIALFIYAQIAHHLGWGVFKEVFRRYGRMNPSSYPNKENDQIDLWYTLLSEVSQLNLASLVDFWKIPLSDKARREMSKFQPFLPDDDVMRMAPERTHMILAKYHSNCLRQ 929
BLAST of Peptidase M60 domain-containing protein vs. TrEMBL
Match: A0A1S3KG34 (TRPM8 channel-associated factor 2 OS=Lingula unguis OX=7574 GN=LOC106181552 PE=4 SV=1) HSP 1 Score: 206.838 bits (525), Expect = 5.357e-52 Identity = 131/439 (29.84%), Postives = 227/439 (51.71%), Query Frame = 2
Query: 1838 PALSLYPGKFQSTNPPFVNIKMKLNLLYKYEVAPLGLYLYPRLKTPVKIIQSKSTRCY---IYVNHHHFNIADKSEV-TKWPVTYKYFTIERGKWET-IQFPFGGLMSISCNENNDKVEIIFKNVIQIPYYDRRNKD---EWIQKQKIESPWAVLAGDAVVFILASTAIRNLADPETILQMYDSMFKEEFHLRGTSFPFSRRGIVSSDIQIGVGYMHSGYPIGTQ--IYHNNNPYKSG--YFFNKEILKKDGAWGLMHEMGHNLQXXXXXXXXXXXXXXXIFSIIATESMTNQNSWSQTSGWFHERLTIERVQKYLISGTFDNNWRENHFVALCIYAQIKNYFGWEFYAQVFRRYNALTHKQRSISEDE--KIQLWIKITSEISGMNLCPLYELWKWPITNQTEQELSKLPMFLPDDFVTKSVEKRIKEIICKRGSIFR 3112
P + ++PG F S PP +++ L ++ ++ G Y+ V + + T I + H ++ + E +WP +E K T + P+GGL+ E N ++ +I NV++ P++D + +W +++ W LAG +VF + ST++R + DP TIL ++DS + LRGT F +R V +D Q GYMH+GYPI T + N Y + F++ +K G WGL HE+GHN+Q +TF+G GE T NIF++ E++T ++W+ + ++ E++ + L + N+W+++ F ALC+Y+Q+ + FGW + VFR Y K+ ++D+ KI ++ SEI NL P+ + W P++ L+ P FLP+D +T + + R+ +++ I R
Sbjct: 286 PGIDVFPGDF-SFKPPLQTVRLNLTTKHRQRLS-TGYYVPAGQPVKVAVTSDQGTDLSGWKICIGAHDDSLVNVKEPWRRWP---DVAVLEELKATTALSSPYGGLLFFDSPERNAELTVIVCNVVEAPFFDLTKPEIVEDWSRRRNAPGLWTELAGRHIVFTVPSTSVREIDDPTTILALWDSAVAAQHDLRGTDPNFQKRERVVADEQPSAGYMHAGYPIVTHLDVVDPNFQYNGSDNFVFSESGMKLYGNWGLFHEIGHNMQRKAWTFSGMGEVTNNIFTLYTYEAVTGNDAWNNPT---MKKFRAEKLPRLLQTQPSLNDWKKDPFFALCVYSQLAHEFGWGSFKTVFRLYENSVKKEEESNQDDGAKIDMYFGRFSEIVRHNLSPMCDFWGIPLSTGVRNNLTLFPAFLPNDEITAAGQARVDQVLPNYPGIVR 716
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Cavefish
Match: si:ch211-210b2.3 (si:ch211-210b2.3 [Source:ZFIN;Acc:ZDB-GENE-131122-13]) HSP 1 Score: 130.183 bits (326), Expect = 3.283e-30 Identity = 142/587 (24.19%), Postives = 245/587 (41.74%), Query Frame = 2
Query: 1367 EYIKSGLRIIIGFESWSYIDKIKPLLD-----------SELKILFYAAGVWPSLKYVQDQFQPVTQHSIHTMSLDKKFEYAKINNVTMND----VLAAYREVFDDIYIERSLDKKDFDSMKKVIHDLYTDYWPFIQSLTP--CLNYAISKQSDKGFLKFFSYIL-LSEIGKDLIPPALSLYPGKFQSTNPPFVNIKMKLNLLYKYEVAPLGLYLYPRLKTPVKI---IQSKSTRCYIYVNHHHFNIADKSEVTKWPVTYKYFTIERGKWETIQFPFGGLMSISCNENN--DKVEIIFKNVIQIPYYDRRNKD--EWIQK-QKIESPWAVLAGDAVVFILASTAIRNLADPETILQMYDSMFKEEFHLRGTSFPFSRRGIVSSDIQIGVGYMHSGYPIGTQIYHNNNPYKSGYFFNKEILKKDGAWGLMHEMGHNLQXXX-XXXXXXXXXXXXIFSIIATESMTNQNSWSQTSGWFHERLTIER----VQKYLISGTFDNNWRENHFVALCIYAQIKNYFGWEFYAQVFRRYNALTHKQRSISEDEKIQLWIKITSEISGMNLCPLYELWKWPITNQTEQELSKLPMF 3034
E++ G ++IG +W Y + P + S++ + + + L Q T + H L ++F + D L R ++ ++ D + S+ ++ D+ ++ P C + I DK L S + + + L+P ++ P +N I++ N E GLYL P ++T V + I K + I H AD + + PV ++ F +++ + +GGL+ + D VE+I + I+ PYY W+ + + +PWA L + ++ L S IR L P+ + +FP R + +D+QI G+MH+GYPI I + P N E +K G WG +HE+GHN Q T E T N++S+ E + N S HE ++ ER Q Y + G + W + + AL Y Q+++ FGW+ + +VF Y+ + + + K+ L+ + S++ MNL P ++ W WPI TE LS LP++
Sbjct: 346 EFVAEGGGLLIGGHAW-YWAQCNPNRNVMTECPANHILSKMGLCIMGSTLESGLYPAQQVTAEGTPQAYHFRDLLQRFAGHVTKGQELTDQDHECLKKLRHDCENYLRMQAHDSASYTSVVNLLTDMVK------EAGVPQVCNSCPIESAKDKLLLHVGSEVYKVCQNPDALLPFIITDIPNLPSVSN---ARIRVSANTGDGEEWISTGLYLSPGMRTFVAVPAEIMDKGWQLQIGCQTDHLGHADV--LRRAPVVHERFALDKDMLQVWNL-WGGLIYLIAPPKCKLDGVEVIVQTAIKAPYYKSGETSVANWMNEIRNAPAPWAELEFENIIITLQSEVIRQLDRPDEV-----------------AFPRKERFV--ADVQISHGFMHAGYPI--MILSCSAPE----LVNPESARKFGIWGAIHELGHNQQRWAWEFPPNTTECTCNLWSVYVHEEVLGVNRASA-----HENMSPERRWGRAQSYAMGGRQLDQW--SMWTALETYMQLQDRFGWDAFKKVFTAYHTINNVPGD--NNGKMNLYAETFSKVVNMNLAPFFKAWGWPIQPSTEDALSSLPVW 885
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000051129.1 (pep primary_assembly:Astyanax_mexicanus-2.0:1:5658439:5662219:-1 gene:ENSAMXG00000036822.1 transcript:ENSAMXT00000051129.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 88.1965 bits (217), Expect = 4.264e-19 Identity = 66/213 (30.99%), Postives = 101/213 (47.42%), Query Frame = 2
Query: 2408 FSRRGIVSSDIQIGVGYMHSGYPIGTQIYHNN---NPYKSGYFFNKEILKKDGAWGLMHEMGHNLQXXX-XXXXXXXXXXXXIFSIIATESMTNQNSWSQTSGWFHERLTIERVQKYLISGTFDNNWRENHFVALCIYAQIKNYFGWEFYAQVFRRYNALTHKQRSISEDEK--IQLWIKITSEISGMNLCPLYELWKWPITNQTEQELSKLP 3028
F R+ +D+QI G+MHSGYPI NPY SG K WG +HE+GHN Q T E T N++S+ E + + G + R++KY+ G +W + AL Y Q++ FGW+ + +VF Y+ +T + +D K + L+ + S++ NL P ++ W WPI TE++L LP
Sbjct: 14 FPRKERFVADVQILAGFMHSGYPIMMHTVSAPDLVNPYVSG---------KSDFWGPVHELGHNQQHSDWEFPPYTTECTCNLWSVYVHEVVLGVKK-ADAHGQMTPQRRQNRIKKYIEGGRNLKDW--TVWTALETYMQLQEEFGWDAFKKVFAAYHDMT----GVPQDNKGKMNLYAETFSKVVNRNLTPFFKAWGWPIQPSTEEQLCSLP 210
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Cavefish
Match: mst1 (macrophage stimulating 1 [Source:NCBI gene;Acc:103025427]) HSP 1 Score: 90.5077 bits (223), Expect = 4.738e-18 Identity = 64/195 (32.82%), Postives = 99/195 (50.77%), Query Frame = 2
Query: 77 IEKCRMTTHGREYMGKVDFVKSGQRCIVWKNEYVNQILMDDTFVFDNTSIIGNNYCRNPTNFPNGLWCIIDEMTLEWEHCNIIKCIKDRNWCKDSDKGTEYLGDISHTKSGKLCQPWINFGTHRAYSFPER--NLKFAGNKCRNPDMSKVPWCYYSN-NYQREDCNVPRCD---KEINQPEFFGTYDYLRGLGSN 643
+ KC + G +Y GKV +SG+ C W +++ + D + T+ + NYCRNP G WC + +E CNI C KD C + + G +Y G + HT +G+ CQ W H+ PE+ + N CRNPD S VPWCY ++ + +RE+C++ +C K +P + T + RG G +
Sbjct: 108 VRKC-IVGKGEDYRGKVSKTQSGKTCQQWWSKFPH----DHRWTPSPTNGLELNYCRNPDGDRIGPWCYTTDPERRYESCNIPLC-KDEV-CINCN-GEDYRGQVDHTVNGRECQRWDQQYPHQHIYQPEKYPDKSLDDNYCRNPDASPVPWCYTTDPDVERENCDIRKCSGIPKRRLRPSY--TTNCFRGRGED 292 HSP 2 Score: 75.8702 bits (185), Expect = 1.761e-13 Identity = 50/159 (31.45%), Postives = 73/159 (45.91%), Query Frame = 2
Query: 92 MTTHGREYMGKVDFVKSGQRCIVWKNEYVNQILMDDTFVFDNTSIIGNNYCRNPTNFPNGLWCIIDEMTLEWEHCNIIKC--IKDRNWCKD------SDKGTEYLGDISHTKSGKLCQPWINFGTHRAYSFPE--RNLKFAGNKCRNPDMSKVPWCYYS 538
+ +G +Y G+VD +G+ C W +Y +Q + D + + +NYCRNP P WC + +E E+C+I KC I R +G +Y G ++ T SG CQ W H +P N CRNPD S+ PWC+ S
Sbjct: 193 INCNGEDYRGQVDHTVNGRECQRWDQQYPHQHIYQPEKYPDKS--LDDNYCRNPDASPV-PWCYTTDPDVERENCDIRKCSGIPKRRLRPSYTTNCFRGRGEDYRGKVNETTSGIACQKWDAQFPHEHPFYPHTYECKGLVENYCRNPDGSEAPWCFTS 348
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Cavefish
Match: hgfb (hepatocyte growth factor [Source:NCBI gene;Acc:103033838]) HSP 1 Score: 85.5001 bits (210), Expect = 1.732e-16 Identity = 72/258 (27.91%), Postives = 112/258 (43.41%), Query Frame = 2
Query: 92 MTTHGREYMGKVDFVKSGQRCIVWKNEYVNQILMDDTFVFDNTSIIGNNYCRNPTNFPNGLWCIIDEMTLEWEHCNIIKCIKDRNWCKDS------DKGTEYLGDISHTKSGKLCQPWINFGTHRAYSFPE--RNLKFAGNKCRNPDMSKVPWCYYSN-NYQREDC-NVPRCDKEINQPE--FFGTYDYLRG--LGSNKTIV-----KLDDIYQTVNVTLSIKLESLKSRTLNKSSMWATAYNVECQSDLDEYEYCSI 808
MT +G Y G +D +SG+ C W + ++ L DN + +NYCRNP WC + + WE+C+I +C D ++ D G Y G ++ + G CQ W H P+ R + N CRNPD PWC+ ++ N C N+PRC +PE + G+ + RG + + I+ + + VTLS +LE R +K Y S L ++YC++
Sbjct: 196 MTCNGESYRGPMDHTESGRECQRWDLDEPHKHLFHPKRYPDNG--LKDNYCRNPDGRQR-PWCFTTDPDVPWEYCSIKQCDSDNQSNIETTTTCFRDNGAGYRGTVAVPREGLTCQRWDAQFPHSHSYMPQKYRCKDLSENFCRNPDGRDAPWCFTTDPNIPWAFCKNIPRCGAAATEPEECYKGSEETYRGKQMKTRSGILCAPWRDHSERNKREVVTLSEELEGNFCRNPDKDKHGPWCYT---NSSLVPWDYCTV 447 HSP 2 Score: 75.8702 bits (185), Expect = 1.465e-13 Identity = 58/200 (29.00%), Postives = 93/200 (46.50%), Query Frame = 2
Query: 77 IEKCRMTTHGREYMGKVDFVKSGQRCIVW--KNEYVNQILMDDTFVFDNTSIIGNNYCRNPTNFPNGLWCIIDEMTLEWEHCNIIKCIKDRNWCKDSDKGTEYLGDISHTKSGKLCQPWINFGTHRAYSFPER--NLKFAGNKCRNPDMSKVPWCYYSN-NYQREDCNVPRCDKEINQPEFFGTYDYLR--GLGSNKTIV 655
+++C + T G Y GK+ ++G+ C W + + L D + +N CRNP N G WC + +++CNI +C + C + G Y G + HT+SG+ CQ W H+ P+R + N CRNPD + PWC+ ++ + E C++ +CD + NQ T R G G T+
Sbjct: 109 VKECIIGT-GLNYKGKISKTETGEECQKWDLNTPHEHHFLPRRHKKKD----LRDNLCRNPDNSTTGPWCFTKNPNIRYQNCNIPQCSEVE--CMTCN-GESYRGPMDHTESGRECQRWDLDEPHKHLFHPKRYPDNGLKDNYCRNPDGRQRPWCFTTDPDVPWEYCSIKQCDSD-NQSNIETTTTCFRDNGAGYRGTVA 299 HSP 3 Score: 64.3142 bits (155), Expect = 5.633e-10 Identity = 56/200 (28.00%), Postives = 83/200 (41.50%), Query Frame = 2
Query: 104 GREYMGKVDFVKSGQRCIVWKNEYVN-QILMDDTFVFDNTSIIGNNYCRNPTNFPNGLWCIIDEMTLEWEHC-NIIKCIKDRNWCKDSDKGTE--YLGDISHTKSGKLCQPWINFGTHRAYSFPERNLKFAGNKCRNPDMSK-VPWCYYSNNYQRED-CNVPRCD---------KEINQPEFFGTYDYLRGLGSNKTIVK 658
G Y G V + G C W ++ + M + + S N+CRNP + WC + + W C NI +C ++ KG+E Y G T+SG LC PW + + + GN CRNPD K PWCY +++ D C V CD E++Q F + +R +G +K
Sbjct: 291 GAGYRGTVAVPREGLTCQRWDAQFPHSHSYMPQKYRCKDLS---ENFCRNPDGR-DAPWCFTTDPNIPWAFCKNIPRCGAAATEPEECYKGSEETYRGKQMKTRSGILCAPWRDHSERNKREVVTLSEELEGNFCRNPDKDKHGPWCYTNSSLVPWDYCTVKLCDPLPNALPQKAEVSQASCF-VHKQVRIVGGGPVPIK 485
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000018418.2 (plasminogen [Source:NCBI gene;Acc:103036400]) HSP 1 Score: 83.9593 bits (206), Expect = 6.037e-16 Identity = 59/178 (33.15%), Postives = 79/178 (44.38%), Query Frame = 2
Query: 95 TTHGREYMGKVDFVKSGQRCIVWKNEYVNQILMDDTFVFDNTSIIG--NNYCRNPTNFPNGLWCIIDEMTLEWEHCNIIKC----------IKDRNWCKDSDKGTEYLGDISHTKSGKLCQPWINFGTHR----AYSFPERNLKFAGNKCRNPDMSKVPWCYYSNNYQR-EDCNVPRC 577
T G Y G V +SG+ C W +Q+ + DN G NYCRNP N WC + WE+CN+ C I C + D G+ Y G ++ T SGK CQ W + H +FP +L+ N CRNPD + PWCY ++ R E C + RC
Sbjct: 285 TGDGNTYRGTVSVTESGKTCQSW----ASQLPHKHSRTPDNYPCKGLDQNYCRNPDNE-RKPWCYTTDPETRWEYCNVESCGNEPRPDEPVIAPNEDCYE-DNGSSYRGVMTETISGKKCQAWASMEPHSHVKTPQNFPTADLRR--NLCRNPDGDRAPWCYTTDPSVRWEYCRIERC 454 HSP 2 Score: 81.2629 bits (199), Expect = 3.602e-15 Identity = 54/163 (33.13%), Postives = 78/163 (47.85%), Query Frame = 2
Query: 104 GREYMGKVDFVKSGQRCIVWKNEYVNQILMDDTFVFDNTSIIGNNYCRNPTNFPNGLWCIIDEMTLEWEHCNIIKCIKDRNWCKDSDKGTEYLGDISHTKSGKLCQPWINFGTHR----AYSFPERNLKFAGNKCRNPDMSKVPWCYYSNNYQR-EDCNVPRC 577
G +Y G KSG C W++ + ++ + T + + +N+CRNP G WC + WE+C+I C ++ C G Y G IS T+SG CQ W + H FPE+ L+ N CRNPD PWC+ + +R E C+V RC
Sbjct: 116 GTDYRGTKSKTKSGTLCQRWESTFPHKPNI--TPRSHPKADLESNFCRNPDGDKGGPWCYTTDPAKRWENCDIQDCTEECMHC----SGENYRGKISTTESGLTCQRWDSQKPHNHGYMPSVFPEKYLEE--NYCRNPDGEPKPWCFTESPAKRWEFCSVSRC 270 HSP 3 Score: 62.003 bits (149), Expect = 3.521e-9 Identity = 50/190 (26.32%), Postives = 77/190 (40.53%), Query Frame = 2
Query: 101 HGREYMGKVDFVKSGQRCIVWKN-EYVNQILMDDTFVFDNTSIIGNNYCRNPTNFPNGLWCIIDEMTLEWEHCNIIKC--------------------------IKDRNWCKDSDKGTEYLGDISHTKSGKLCQPWINFGTHRAYSFPERNLK--FAGNKCRNPDMS-KVPWCYYSNNYQRED-CNVPRC 577
+G Y G + SG++C W + E + + F T+ + N CRNP + WC + ++ WE+C I +C + CK + G Y G +S T +G CQ W H + P+ + NKCRNPD PWCY ++ ++ D C +P C
Sbjct: 381 NGSSYRGVMTETISGKKCQAWASMEPHSHVKTPQNFP---TADLRRNLCRNP-DGDRAPWCYTTDPSVRWEYCRIERCGSTTVSLTPPPALKPVVPPTLLTQSVPSEFADCK-TGSGISYRGSVSKTVAGVTCQAWSASTPHLSSFTPQAHPDKGLDSNKCRNPDGDVNGPWCYTTDPNKKWDYCQIPEC 565
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000976.1 (pep scaffold:Pmarinus_7.0:GL479898:35358:38300:-1 gene:ENSPMAG00000000885.1 transcript:ENSPMAT00000000976.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 107.457 bits (267), Expect = 6.623e-24 Identity = 83/336 (24.70%), Postives = 153/336 (45.54%), Query Frame = 2
Query: 2012 IYVNHHHFNIADKSEVTKWPVTYKYFTIERGKWET----IQFPFGGLMSISCNENND--KVEIIFKNVIQIPYY--DRRNKDEWIQ-KQKIESPWAVLAGDAVVFILASTAIRNLADPETILQMYDSMFKEEFHLRGTSFPFSRRGIVSSDIQIGVGYMHSGYPIGTQIYHNNNPYKSGYFFNKEILKKDGAWGLMHEMGHNLQXXX-XXXXXXXXXXXXIFSI-IATESMTNQNSWSQTSGWFHERLTIERVQKYLISGTFDNNWRENHFVALCIYAQIKNYFGWEFYAQVFRRYNALTHKQRSISEDEKIQLWIKITSEISGMNLCPLYELWKW 2986
I + H + D + + P + + RG+ + + +GGL+ + E K+ + + + PY+ + W + ++ +PW+ LA D+++ + S A R LADPE +++++D M +L P +R + D QI G+MH+GYPI + H + K N++ ++ +G WG +HE+GHN Q T E T N+F++ + E + + + ER R++ ++ +G W F L Y Q++ FGW+ + ++F Y ++ + K+ W + S G NL P + W W
Sbjct: 553 IQLGCHTDQLYDSKTMKRHPEVTRSMPVVRGEMDRGAMEVASSWGGLLYLLVPEGVSLGKIRVRVRGAARAPYFKLGETSLQHWQEFERHYPAPWSELACDSLILTVPSEAARGLADPERLMRLWDRMTGAIAYLAAEPHPSARPERIVVDEQISHGWMHAGYPI---MVHRASIPK---LLNEQEMRAEGMWGPLHELGHNRQRPAWNFPPHTTEATNNLFAVYVHEEVLGVARARAHPDLRPAERE--RRLRDHVDAGCPLAAW--TVFTCLETYLQLQEAFGWDPFVRLFGDYQRAASTPSTM--EAKMSEWAERFSRCVGRNLAPFFSAWGW 876
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003778.1 (pep scaffold:Pmarinus_7.0:GL482904:4425:14035:-1 gene:ENSPMAG00000003419.1 transcript:ENSPMAT00000003778.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 78.9518 bits (193), Expect = 3.125e-15 Identity = 54/188 (28.72%), Postives = 84/188 (44.68%), Query Frame = 2
Query: 92 MTTHGREYMGKVDFVKSGQRCIVWKNEYVNQILMDDTFVFDNTSIIGNNYCRNPTNFPNGLWCIIDEMTLEWEHCNIIKCIKDRNW----------CKDSDK---------GTEYLGDISHTKSGKLCQPWINFGTH--RAYSFPERNLKFAGNKCRNPDM-SKVPWCYYSNNYQRED-CNVPRCDKE 586
MT +G +Y+G V F KSG++C +W + + +Q+ V + N+CRNP +G WC + + E C++ C KD N K + + G +Y G ++ T+SG+ CQ W H R R G CRNPD + WCY ++ D C + CD++
Sbjct: 108 MTGNGEQYIGNVSFTKSGRQCQLWTSNFPHQVRFKP--VDHPEKQLVENFCRNPDASQDGPWCYTRDPLVPREPCSVPTCDKDPNQHVPVSPRVTPTKPAPRPQGPCVPGAGEDYRGPVNVTRSGRHCQAWSAQTPHVSRYSPLTHRAAGLEGAACRNPDGDEEGAWCYTTDPGLTIDYCALHYCDED 293 HSP 2 Score: 63.929 bits (154), Expect = 1.310e-10 Identity = 36/82 (43.90%), Postives = 48/82 (58.54%), Query Frame = 2
Query: 368 GTEYLGDISHTKSGKLCQPWINFGTH----RAYSFPERNLKFAGNKCRNPDMSK-VPWCYYSNNY-QREDCNVPRCDKEINQ 595
G +Y+G++S TKSG+ CQ W + H + PE+ L N CRNPD S+ PWCY + RE C+VP CDK+ NQ
Sbjct: 112 GEQYIGNVSFTKSGRQCQLWTSNFPHQVRFKPVDHPEKQL--VENFCRNPDASQDGPWCYTRDPLVPREPCSVPTCDKDPNQ 191
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Sea Lamprey
Match: hgfb (hepatocyte growth factor b [Source:ZFIN;Acc:ZDB-GENE-041014-3]) HSP 1 Score: 71.2478 bits (173), Expect = 6.174e-13 Identity = 79/306 (25.82%), Postives = 123/306 (40.20%), Query Frame = 2
Query: 104 GREYMGKVDFVKSGQRCIVWKNEYV-NQILMDDTFVFDNTSIIGNNYCRNPTNFPNGL---WCIIDEMTLEWEHCNI---------IKCIKDRNWCKDSDKGTEYLGDISHTKSGKLCQPWINFGTHRAYSFPERNLKFAG---NKCRNPD-MSKVPWCY-YSNNYQREDC-NVPRCDKEINQPEFF---GTYDYLRGLGSNKTIVKLDDIYQTVNVTLSIKLESLKSRTLNKSSMWATAYNVECQS-DLDEYEYCSITSSTNTSQDYIITYLCSGPLKYLMFISLLQKSDFTIKHAGAKYPKPSP 952
G Y G VD S + C W ++ N D F + + +NYCRNP NG WC + WE+C+I + + C + ++G +Y G +HTK G CQ W HR +++ E N +G N CRNPD + PWC+ + +R+ C ++PRC + + + GT Y G+ + + ++ Q N T K KS A C++ D D + TS + DY C + + F + G K+P +P
Sbjct: 139 GEHYRGLVDHTDSQRECQRWDLQHPHNHNYTPDRFP---NAGLDDNYCRNP----NGRMRPWCFTTDPHQPWEYCSIKPGCCASKATRPAMEGRPCLE-ERGEDYRGRANHTKGGIPCQHWAAQQPHR-HTYLEHNYPCSGLDRNYCRNPDGREEAPWCFTLDPSVRRQLCSHIPRCAQPTAGSQCYSGSGTA-YRGGVATTRHGLQC----QAWNAT-----SPHKPWYTPKSHPGAGLEGHSCRNPDGDPWGPWCFTSDPHLPWDYCSVEACGDNFPLSSLLDSPPGTQFGKHNCGLKHPSKAP 425 HSP 2 Score: 67.781 bits (164), Expect = 5.962e-12 Identity = 53/188 (28.19%), Postives = 77/188 (40.96%), Query Frame = 2
Query: 5 FMLSAQLSVIFSLQYVIFAGYFEEIEKCR--MTTHGREYMGKVDFVKSGQRCIVWKNEYVNQILMDDTF--VFDNTSIIGNNYCRNPTNFPNGLWCIIDEMTLEWEHCNIIKCIKDRNWCKDSDKGTEYLGDISHTKSGKLCQPWINFGTHRAYSFPER--NLKFAGNKCRNPDMSKVPWCYYSNNYQ 550
+ S S ++ I +E E R T +G Y G ++ +SG C W + + +F FD + N CRNP P WC + E C I +C D C + +G Y G + HT S + CQ W H P+R N N CRNP+ PWC+ ++ +Q
Sbjct: 21 LLDSTSRSQGVTVHCDILTDLYERKEYVRGCYTGNGSGYRGDKNYTESGLPCQAWGDSEPHDSRYLPSFYPAFD----LEGNSCRNPAQEPGEPWCYTMDSNRRRERCGIPRC--DEVPCVEC-RGEHYRGLVDHTDSQRECQRWDLQHPHNHNYTPDRFPNAGLDDNYCRNPNGRMRPWCFTTDPHQ 201 HSP 3 Score: 54.299 bits (129), Expect = 1.190e-7 Identity = 36/93 (38.71%), Postives = 48/93 (51.61%), Query Frame = 2
Query: 368 GTEYLGDISHTKSGKLCQPWINFGTHRAYSFPE--RNLKFAGNKCRNPDMSK-VPWCY-YSNNYQREDCNVPRCDKEINQPEFFGTYDYLRGL 634
G+ Y GD ++T+SG CQ W + H + P GN CRNP PWCY +N +RE C +PRCD E+ E G ++ RGL
Sbjct: 56 GSGYRGDKNYTESGLPCQAWGDSEPHDSRYLPSFYPAFDLEGNSCRNPAQEPGEPWCYTMDSNRRRERCGIPRCD-EVPCVECRG--EHYRGL 145
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001728.1 (pep scaffold:Pmarinus_7.0:GL477419:32233:56220:-1 gene:ENSPMAG00000001561.1 transcript:ENSPMAT00000001728.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 54.299 bits (129), Expect = 4.869e-8 Identity = 28/90 (31.11%), Postives = 43/90 (47.78%), Query Frame = 2
Query: 71 EEIEKCRMTTHGREYMGKVDFVKSGQRCIVWKNEYVN-QILMDDTFVFDNTSIIGNNYCRNPTNFPNGLWCIIDEMTLEWEHCNIIKCIK 337
E ++ C T G Y G SG +C W ++ + + F + + NNYCRNP + PNG WCI + + WE+C + +C
Sbjct: 6 EWVDHC-YTGSGTGYRGLQTLTASGHQCQTWASKTPHLHAYTPEGFP---EAGLENNYCRNPDSDPNGPWCITQDPNVLWEYCALQRCAS 91
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Nematostella
Match: EDO39763 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S935]) HSP 1 Score: 51.2174 bits (121), Expect = 5.615e-8 Identity = 34/79 (43.04%), Postives = 41/79 (51.90%), Query Frame = 2
Query: 365 KGTEYLGDISHTKSGKLCQPWINFGTHRAY--SFPERNLKFAGNKCRNPD--MSKVPWCYYSNNYQR-EDCNVPRCDKE 586
+G Y G+I+ TKSG CQPW + HR Y S L A N CRNP PWCY +N R E C+VP+C
Sbjct: 15 EGVGYHGNINVTKSGISCQPWSSQCPHRHYHNSTQYTELINASNFCRNPGGMGPDGPWCYTTNMMVRWEYCDVPKCPPP 93 HSP 2 Score: 49.6766 bits (117), Expect = 2.133e-7 Identity = 25/77 (32.47%), Postives = 40/77 (51.95%), Query Frame = 2
Query: 104 GREYMGKVDFVKSGQRCIVWKNEYVNQILMDDTFVFDNTSIIGNNYCRNPTNF-PNGLWCIIDEMTLEWEHCNIIKC 331
G Y G ++ KSG C W ++ ++ + T + I +N+CRNP P+G WC M + WE+C++ KC
Sbjct: 16 GVGYHGNINVTKSGISCQPWSSQCPHRHYHNSTQYTE--LINASNFCRNPGGMGPDGPWCYTTNMMVRWEYCDVPKC 90
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Nematostella
Match: EDO28926 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T536]) HSP 1 Score: 50.447 bits (119), Expect = 7.364e-8 Identity = 34/78 (43.59%), Postives = 42/78 (53.85%), Query Frame = 2
Query: 365 KGTEYLGDISHTKSGKLCQPWINFGTHRAY----SFPERNLKFAGNKCRNPD--MSKVPWCYYSNNYQR-EDCNVPRC 577
+G Y G+I+ TKSG CQPW + H Y +PE L A N CRNP PWCY +N R E C+VP+C
Sbjct: 6 EGVGYHGNINVTKSGISCQPWSSQCPHHHYHNSTQYPE--LINASNFCRNPGGMGPDGPWCYTTNKLVRWEYCDVPKC 81 HSP 2 Score: 46.595 bits (109), Expect = 1.399e-6 Identity = 24/77 (31.17%), Postives = 38/77 (49.35%), Query Frame = 2
Query: 104 GREYMGKVDFVKSGQRCIVWKNEYVNQILMDDTFVFDNTSIIGNNYCRNPTNF-PNGLWCIIDEMTLEWEHCNIIKC 331
G Y G ++ KSG C W ++ + + T + I +N+CRNP P+G WC + WE+C++ KC
Sbjct: 7 GVGYHGNINVTKSGISCQPWSSQCPHHHYHNSTQYPE--LINASNFCRNPGGMGPDGPWCYTTNKLVRWEYCDVPKC 81
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Nematostella
Match: EDO30193 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T1H4]) HSP 1 Score: 49.6766 bits (117), Expect = 1.460e-7 Identity = 25/82 (30.49%), Postives = 38/82 (46.34%), Query Frame = 2
Query: 104 GREYMGKVDFVKSGQRCIVWKNEYVNQ-ILMDDTFVFDNTSIIGNNYCRNPTNFPNGLWCIIDEMTLEWEHCNIIKCIKDRN 346
GR+Y G ++F G C W ++ +Q M D V + +NYCRNP + WC W++C I C K ++
Sbjct: 2 GRDYRGTMNFTAKGVTCQPWNEQWPHQHTEMADPLVAAREGLGKHNYCRNPGGRKHRPWCYTTLEKTRWQYCEIRSCRKTKS 83
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Medaka
Match: si:ch211-210b2.3 (TRPM8 channel-associated factor homolog [Source:NCBI gene;Acc:101159605]) HSP 1 Score: 137.117 bits (344), Expect = 2.398e-32 Identity = 110/375 (29.33%), Postives = 173/375 (46.13%), Query Frame = 2
Query: 1943 GLYLYPRLKT----PVKIIQSKSTRCYIYVNHHHFNIADKSEVTKWPVTYKYFTIERGKWETIQFPFGGLMSISCNENND--KVEIIFKNVIQIPYYDR--RNKDEWIQKQKIESPWAVLAGDAVVFILASTAIRNLADPETILQMYDSMFKEEFHLRGTSFPFSRRGIVSSDIQIGVGYMHSGYPIGTQIYHNNNPYKSGYFFNKEILKKDGAWGLMHEMGHNLQXXX-XXXXXXXXXXXXIFSIIATESMTNQNSWSQTSGWFHERLTIE----RVQKYLISGTFDNNWRENHFVALCIYAQIKNYFGWEFYAQVFRRYNALTHKQRSISEDEKIQLWIKITSEISGMNLCPLYELWKWPITNQTEQELSKLP 3028
GLYL P +KT P +++Q K + I N E+ + P ++ F + + +GGL+ + D VE+I + + PYY + W + SPWA L D ++ + S A+R L PE + Q+++ + K L F R+ +D+QI G+MH+GYPI Q N N + +K G WG +HE+GHN Q G T E T N++S+ E + + H +++E R + Y+ G N+W +VAL Y Q+++ FGW+ + +VF Y L Q K+ L+ + S+ GM+L ++ W WPI TEQ+LS LP
Sbjct: 551 GLYLSPGMKTYISIPAQMVQ-KGWQIQIGCQTDQLN---AEELKRPPRVHEQFAVTSEMMQVWNL-WGGLIYLVAPPQADVHGVEVIVQMAVPAPYYKSGVTTAEAWSLLRTAPSPWAELEFDNIILTVPSEAVRTLERPEELAQLWNKIMKAIADLAAKPEKFPRKERFVADVQISHGWMHAGYPIMGQKSAVNE------LVNVDHMKSCGLWGPIHELGHNQQRGCWEFPPNTTECTCNLWSVYVHEEVLGIDRAKA-----HPNMSLENRKSRARNYVTQGRNLNSWE--MWVALETYMQLQDKFGWDAFKKVFAAY--LQMSQFPGDNPGKMNLYTETFSQTVGMDLTAFFKAWGWPIQASTEQKLSNLP 905
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Medaka
Match: mst1 (hepatocyte growth factor-like protein [Source:NCBI gene;Acc:101168450]) HSP 1 Score: 91.6633 bits (226), Expect = 2.002e-18 Identity = 70/208 (33.65%), Postives = 98/208 (47.12%), Query Frame = 2
Query: 104 GREYMGKVDFVKSGQRCIVWKNEYVNQILMDDTFVFDNTSIIGNNYCRNPTNFPNGLWCIIDEMTLEWEHCNIIKCIKDRNWCKD----SDKGTEYLGDISHTKSGKLCQPWINFGTHRAYSFPER--NLKFAGNKCRNPDMSKVPWCYYSNN-YQREDCNVPRCDK---EINQPEFFGTYDYLRGLGSNKTIVKLDDIYQTVNVTLS 697
G +Y GKV KSG C W +++ + D + ++ + NYCRNP G WC + +E CNI + CKD + G +Y G + HT +GK CQ W H+ PE+ + N CRNPD S VPWCY ++ +RE+CN+ +C + E Q F T + RG G +D VN TLS
Sbjct: 114 GEDYRGKVFTTKSGLNCQQWWSKFPH----DHWWTPTASNGLELNYCRNPDGDNIGPWCYTTDPERRYESCNIPQ-------CKDEVCITCNGEDYRGQVDHTATGKECQRWDQQHPHQHIYQPEKYPDKSLDDNYCRNPDASPVPWCYTTDPLVERENCNISKCPEVPVEKRQRSSF-TTNCFRGRG--------EDYRGKVNETLS 301 HSP 2 Score: 76.2554 bits (186), Expect = 1.305e-13 Identity = 74/290 (25.52%), Postives = 119/290 (41.03%), Query Frame = 2
Query: 92 MTTHGREYMGKVDFVKSGQRCIVWKNEYVNQILMDDTFVFDNTSIIGNNYCRNPTNFPNGLWCIIDEMTLEWEHCNIIKC----IKDRNWCKDS-------DKGTEYLGDISHTKSGKLCQPWINFGTHRAYSFPE--RNLKFAGNKCRNPDMSKVPWCYYSNNYQRED--CNVPRCDKEINQPEFFGTYDY-LRGLGSNKTIVKLDDIYQTVNVTLSIKLESLKSRTLNKSSMWATAYNVECQSDLDEYEYCSITSSTNTSQDYIITYLCSGPLKYLMFISLLQKSDFT 913
+T +G +Y G+VD +G+ C W ++ +Q + D + + +NYCRNP P WC + +E E+CNI KC ++ R + S +G +Y G ++ T SG CQ W H P N CRNPD S+ PWC+ S R + RC+ +I + + RG+ KT + VN K+ L N + + D D++ T+ T DY C+G + + ++K +F+
Sbjct: 191 ITCNGEDYRGQVDHTATGKECQRWDQQHPHQHIYQPEKYPDKS--LDDNYCRNPDASPV-PWCYTTDPLVERENCNISKCPEVPVEKRQ--RSSFTTNCFRGRGEDYRGKVNETLSGIPCQRWNAQFPHEHPFHPNIYECKGLEENYCRNPDGSEAPWCFTSAPEMRTALCLQIKRCEDDIEAEDCYQENGKNYRGI-VRKTRKGVTCQRWNVNTPHRTKINPLTHPEANLTENYCR------NPDGDQHGPWCYTTDPKTEFDYCAIKQCAG--EKVSLTEQIEKVEFS 466 HSP 3 Score: 56.225 bits (134), Expect = 1.866e-7 Identity = 33/92 (35.87%), Postives = 48/92 (52.17%), Query Frame = 2
Query: 365 KGTEYLGDISHTKSGKLCQPWINFGTHRAYSFPERNLKFAGNKCRNPDMSKV-PWCYYSNNYQR-EDCNVPRCDKEI----NQPEFFGTYDY 622
KG +Y G + TKSG CQ W + H + P + N CRNPD + PWCY ++ +R E CN+P+C E+ N ++ G D+
Sbjct: 113 KGEDYRGKVFTTKSGLNCQQWWSKFPHDHWWTPTASNGLELNYCRNPDGDNIGPWCYTTDPERRYESCNIPQCKDEVCITCNGEDYRGQVDH 204
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Medaka
Match: plat (plasminogen activator, tissue type [Source:NCBI gene;Acc:100049466]) HSP 1 Score: 76.6406 bits (187), Expect = 6.757e-14 Identity = 63/192 (32.81%), Postives = 84/192 (43.75%), Query Frame = 2
Query: 56 FAGYFEEI---EKCRMTTHGREYMGKVDFVKSGQRCIVWKNEYVNQILMDDTFVFDNTSIIG-----NNYCRNPTNFPNGLWCIIDEMT-LEWEHCNIIKCIKDRNWCKDSDKGTEYLGDISHTKSGKLCQPWINFGTHR----AYSFPERNLKFAG-NKCRNPDMSKVPWCYYSNNYQR--EDCNVPRCDK 583
F G EI EKC + G Y G + SG+ CI W + L F T G +N+CRNP + + WC I + T + WE C++ KC DRN G Y G + TKSG C PW R A+ +L + N CRNPD PWC+ Q E C++P+C +
Sbjct: 65 FKGAQCEINSNEKC-IVGKGEGYRGTLSVTHSGEECINWNSTS----LRGKKFTARKTDASGLGLGNHNFCRNP-DQDSAPWCYIYKGTQVIWELCSLPKCSGDRNRECVQGLGKSYRGTAAVTKSGSACLPWDAPAVRRKRNNAWKSNALDLGLSNHNFCRNPDGDSGPWCHTYKKMQLTWELCDIPKCSR 250
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Medaka
Match: plat (plasminogen activator, tissue type [Source:NCBI gene;Acc:100049466]) HSP 1 Score: 76.2554 bits (186), Expect = 9.107e-14 Identity = 63/192 (32.81%), Postives = 84/192 (43.75%), Query Frame = 2
Query: 56 FAGYFEEI---EKCRMTTHGREYMGKVDFVKSGQRCIVWKNEYVNQILMDDTFVFDNTSIIG-----NNYCRNPTNFPNGLWCIIDEMT-LEWEHCNIIKCIKDRNWCKDSDKGTEYLGDISHTKSGKLCQPWINFGTHR----AYSFPERNLKFAG-NKCRNPDMSKVPWCYYSNNYQR--EDCNVPRCDK 583
F G EI EKC + G Y G + SG+ CI W + L F T G +N+CRNP + + WC I + T + WE C++ KC DRN G Y G + TKSG C PW R A+ +L + N CRNPD PWC+ Q E C++P+C +
Sbjct: 137 FKGAQCEINSNEKC-IVGKGEGYRGTLSVTHSGEECINWNSTS----LRGKKFTARKTDASGLGLGNHNFCRNP-DQDSAPWCYIYKGTQVIWELCSLPKCSGDRNRECVQGLGKSYRGTAAVTKSGSACLPWDAPAVRRKRNNAWKSNALDLGLSNHNFCRNPDGDSGPWCHTYKKMQLTWELCDIPKCSR 322
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Medaka
Match: plat (plasminogen activator, tissue type [Source:NCBI gene;Acc:100049466]) HSP 1 Score: 76.2554 bits (186), Expect = 9.902e-14 Identity = 63/192 (32.81%), Postives = 84/192 (43.75%), Query Frame = 2
Query: 56 FAGYFEEI---EKCRMTTHGREYMGKVDFVKSGQRCIVWKNEYVNQILMDDTFVFDNTSIIG-----NNYCRNPTNFPNGLWCIIDEMT-LEWEHCNIIKCIKDRNWCKDSDKGTEYLGDISHTKSGKLCQPWINFGTHR----AYSFPERNLKFAG-NKCRNPDMSKVPWCYYSNNYQR--EDCNVPRCDK 583
F G EI EKC + G Y G + SG+ CI W + L F T G +N+CRNP + + WC I + T + WE C++ KC DRN G Y G + TKSG C PW R A+ +L + N CRNPD PWC+ Q E C++P+C +
Sbjct: 97 FKGAQCEINSNEKC-IVGKGEGYRGTLSVTHSGEECINWNSTS----LRGKKFTARKTDASGLGLGNHNFCRNP-DQDSAPWCYIYKGTQVIWELCSLPKCSGDRNRECVQGLGKSYRGTAAVTKSGSACLPWDAPAVRRKRNNAWKSNALDLGLSNHNFCRNPDGDSGPWCHTYKKMQLTWELCDIPKCSR 282
BLAST of Peptidase M60 domain-containing protein vs. Planmine SMEST
Match: SMESG000026361.1 (SMESG000026361.1) HSP 1 Score: 2077.75 bits (5382), Expect = 0.000e+0 Identity = 1034/1038 (99.61%), Postives = 1035/1038 (99.71%), Query Frame = 2
Query: 92 MTTHGREYMGKVDFVKSGQRCIVWKNEYVNQILMDDTFVFDNTSIIGNNYCRNPTNFPNGLWCIIDEMTLEWEHCNIIKCIKDRNWCKDSDKGTEYLGDISHTKSGKLCQPWINFGTHRAYSFPERNLKFAGNKCRNPDMSKVPWCYYSNNYQREDCNVPRCDKEINQPEFFGTYDYLRGLGSNKTIVKLDDIYQTVNVTLSIKLESLKSRTLNKSSMWATAYNVECQSDLDEYEYCSITSSTNTSQDYIITYLCSGPLKYLMFISLLQKSDFTIKHAGAKYPKPSPSKQFNEYEKKMKEYYQNKNKNKFNLTLGEYPGYFYLLKDNAIAYAMNAKNKISMTLSTVGKGRIAFMGSDDLINVKPYKILLDFFQDVFDKPVESPTLLNKSYLQEIISKNKSQSVLSEPFIWNAEQVFGQDLVKVLLEYIKSGLRIIIGFESWSYIDKIKPLLDSELKILFYAAGVWPSLKYVQDQFQPVTQHSIHTMSLDKKFEYAKINNVTMNDVLAAYREVFDDIYIERSLDKKDFDSMKKVIHDLYTDYWPFIQSLTPCLNYAISKQSDKGFLKFFSYILLSEIGKDLIPPALSLYPGKFQSTNPPFVNIKMKLNLLYKYEVAPLGLYLYPRLKTPVKIIQSKSTRCYIYVNHHHFNIADKSEVTKWPVTYKYFTIERGKWETIQFPFGGLMSISCNENNDKVEIIFKNVIQIPYYDRRNKDEWIQKQKIESPWAVLAGDAVVFILASTAIRNLADPETILQMYDSMFKEEFHLRGTSFPFSRRGIVSSDIQIGVGYMHSGYPIGTQIYHNNNPYKSGYFFNKEILKKDGAWGLMHEMGHNLQXXXXXXXXXXXXXXXIFSIIATESMTNQNSWSQTSGWFHERLTIERVQKYLISGTFDNNWRENHFVALCIYAQIKNYFGWEFYAQVFRRYNALTHKQRSISEDEKIQLWIKITSEISGMNLCPLYELWKWPITNQTEQELSKLPMFLPDDFVTKSVEKRIKEIICKRGSIFRQXXXXXXXXXXXXXXFTVEGAKIIEQIQILN 3205
MTTHGREYMGKVDFVKSGQRCIVWKNEYVNQILMDDTFVFDNTSIIGNNYCRNPTNFPNGLWCIIDEMTLEWEHCNIIKCIKDRNWCKDSDKGTEYLGDISHTKSGKLCQPWINFGTHRAYSFPERNLKFAGNKCRNPDMSKVPWCYYSNNYQREDCNVPRCDKEINQPEFFGTYDYLRGLGSNKTIVKLDDIYQTVNVTLSIKLESLKSRTLNKSSMWATAYNVECQSDLDEYEYCSITSSTNTSQDYIITYLCSGPLKYLMFISLLQKSDFTIKHAGAKYPKPSPSKQFNEYEKKMKEYYQNKNKNKFNLTLGEYPGYFYLLKDNAIAYAMNAKNKISMTLSTVGKGRIAFMGSDDLINVKPYKILLDFFQDVFDKPVESPTLLNKSYLQEIISKNKSQSVLSEPFIWNAEQVFGQDLVKVLLEYIKSGLRIIIGFESWSYIDKIKPLLDSELKILFYAAGVWPSLKYVQDQFQPVTQHSIHTMSLDKKFEYAKINNVTMNDVLAAYREVFDDIYIERSLDK DFD MKKVI+DLYTDYWPFIQSLTPCLNYAISKQSDKGFLKFFSYILLSEIGKDLIPPALSLYPGKFQSTNPPFVNIKMKLNLLYKYEVAPLGLYLYPRLKTPVKIIQSKSTRCYIYVNHHHFNIADKSEVTKWPVTYKYFTIERGKWETIQFPFGGLMSISCNENNDKVEIIFKNVIQIPYYDRRNKDEWIQKQKIESPWAVLAGDAVVFILASTAIRNLADPETILQMYDSMFKEEFHLRGTSFPFSRRGIVSSDIQIGVGYMHSGYPIGTQIYHNNNPYKSGYFFNKEILKKDGAWGLMHEMGHNLQEGTFTFNGTGETTTNIFSIIATESMTNQNSWSQTSGWFHERLTIERVQKYLISGTFDNNWRENHFVALCIYAQIKNYFGWEFYAQVFRRYNALTHKQRSISEDEKIQLWIKITSEISGMNLCPLYELWKWPITNQTEQELSKLPMFLPDDFVTKSVEKRIKEIICKRGSIFRQPLPVPVKVGPVKNKFTVEGAKIIE IQILN
Sbjct: 1 MTTHGREYMGKVDFVKSGQRCIVWKNEYVNQILMDDTFVFDNTSIIGNNYCRNPTNFPNGLWCIIDEMTLEWEHCNIIKCIKDRNWCKDSDKGTEYLGDISHTKSGKLCQPWINFGTHRAYSFPERNLKFAGNKCRNPDMSKVPWCYYSNNYQREDCNVPRCDKEINQPEFFGTYDYLRGLGSNKTIVKLDDIYQTVNVTLSIKLESLKSRTLNKSSMWATAYNVECQSDLDEYEYCSITSSTNTSQDYIITYLCSGPLKYLMFISLLQKSDFTIKHAGAKYPKPSPSKQFNEYEKKMKEYYQNKNKNKFNLTLGEYPGYFYLLKDNAIAYAMNAKNKISMTLSTVGKGRIAFMGSDDLINVKPYKILLDFFQDVFDKPVESPTLLNKSYLQEIISKNKSQSVLSEPFIWNAEQVFGQDLVKVLLEYIKSGLRIIIGFESWSYIDKIKPLLDSELKILFYAAGVWPSLKYVQDQFQPVTQHSIHTMSLDKKFEYAKINNVTMNDVLAAYREVFDDIYIERSLDKIDFDLMKKVINDLYTDYWPFIQSLTPCLNYAISKQSDKGFLKFFSYILLSEIGKDLIPPALSLYPGKFQSTNPPFVNIKMKLNLLYKYEVAPLGLYLYPRLKTPVKIIQSKSTRCYIYVNHHHFNIADKSEVTKWPVTYKYFTIERGKWETIQFPFGGLMSISCNENNDKVEIIFKNVIQIPYYDRRNKDEWIQKQKIESPWAVLAGDAVVFILASTAIRNLADPETILQMYDSMFKEEFHLRGTSFPFSRRGIVSSDIQIGVGYMHSGYPIGTQIYHNNNPYKSGYFFNKEILKKDGAWGLMHEMGHNLQEGTFTFNGTGETTTNIFSIIATESMTNQNSWSQTSGWFHERLTIERVQKYLISGTFDNNWRENHFVALCIYAQIKNYFGWEFYAQVFRRYNALTHKQRSISEDEKIQLWIKITSEISGMNLCPLYELWKWPITNQTEQELSKLPMFLPDDFVTKSVEKRIKEIICKRGSIFRQPLPVPVKVGPVKNKFTVEGAKIIEHIQILN 1038
BLAST of Peptidase M60 domain-containing protein vs. Planmine SMEST
Match: SMESG000026361.1 (SMESG000026361.1) HSP 1 Score: 2058.88 bits (5333), Expect = 0.000e+0 Identity = 1026/1030 (99.61%), Postives = 1027/1030 (99.71%), Query Frame = 2
Query: 116 MGKVDFVKSGQRCIVWKNEYVNQILMDDTFVFDNTSIIGNNYCRNPTNFPNGLWCIIDEMTLEWEHCNIIKCIKDRNWCKDSDKGTEYLGDISHTKSGKLCQPWINFGTHRAYSFPERNLKFAGNKCRNPDMSKVPWCYYSNNYQREDCNVPRCDKEINQPEFFGTYDYLRGLGSNKTIVKLDDIYQTVNVTLSIKLESLKSRTLNKSSMWATAYNVECQSDLDEYEYCSITSSTNTSQDYIITYLCSGPLKYLMFISLLQKSDFTIKHAGAKYPKPSPSKQFNEYEKKMKEYYQNKNKNKFNLTLGEYPGYFYLLKDNAIAYAMNAKNKISMTLSTVGKGRIAFMGSDDLINVKPYKILLDFFQDVFDKPVESPTLLNKSYLQEIISKNKSQSVLSEPFIWNAEQVFGQDLVKVLLEYIKSGLRIIIGFESWSYIDKIKPLLDSELKILFYAAGVWPSLKYVQDQFQPVTQHSIHTMSLDKKFEYAKINNVTMNDVLAAYREVFDDIYIERSLDKKDFDSMKKVIHDLYTDYWPFIQSLTPCLNYAISKQSDKGFLKFFSYILLSEIGKDLIPPALSLYPGKFQSTNPPFVNIKMKLNLLYKYEVAPLGLYLYPRLKTPVKIIQSKSTRCYIYVNHHHFNIADKSEVTKWPVTYKYFTIERGKWETIQFPFGGLMSISCNENNDKVEIIFKNVIQIPYYDRRNKDEWIQKQKIESPWAVLAGDAVVFILASTAIRNLADPETILQMYDSMFKEEFHLRGTSFPFSRRGIVSSDIQIGVGYMHSGYPIGTQIYHNNNPYKSGYFFNKEILKKDGAWGLMHEMGHNLQXXXXXXXXXXXXXXXIFSIIATESMTNQNSWSQTSGWFHERLTIERVQKYLISGTFDNNWRENHFVALCIYAQIKNYFGWEFYAQVFRRYNALTHKQRSISEDEKIQLWIKITSEISGMNLCPLYELWKWPITNQTEQELSKLPMFLPDDFVTKSVEKRIKEIICKRGSIFRQXXXXXXXXXXXXXXFTVEGAKIIEQIQILN 3205
MGKVDFVKSGQRCIVWKNEYVNQILMDDTFVFDNTSIIGNNYCRNPTNFPNGLWCIIDEMTLEWEHCNIIKCIKDRNWCKDSDKGTEYLGDISHTKSGKLCQPWINFGTHRAYSFPERNLKFAGNKCRNPDMSKVPWCYYSNNYQREDCNVPRCDKEINQPEFFGTYDYLRGLGSNKTIVKLDDIYQTVNVTLSIKLESLKSRTLNKSSMWATAYNVECQSDLDEYEYCSITSSTNTSQDYIITYLCSGPLKYLMFISLLQKSDFTIKHAGAKYPKPSPSKQFNEYEKKMKEYYQNKNKNKFNLTLGEYPGYFYLLKDNAIAYAMNAKNKISMTLSTVGKGRIAFMGSDDLINVKPYKILLDFFQDVFDKPVESPTLLNKSYLQEIISKNKSQSVLSEPFIWNAEQVFGQDLVKVLLEYIKSGLRIIIGFESWSYIDKIKPLLDSELKILFYAAGVWPSLKYVQDQFQPVTQHSIHTMSLDKKFEYAKINNVTMNDVLAAYREVFDDIYIERSLDK DFD MKKVI+DLYTDYWPFIQSLTPCLNYAISKQSDKGFLKFFSYILLSEIGKDLIPPALSLYPGKFQSTNPPFVNIKMKLNLLYKYEVAPLGLYLYPRLKTPVKIIQSKSTRCYIYVNHHHFNIADKSEVTKWPVTYKYFTIERGKWETIQFPFGGLMSISCNENNDKVEIIFKNVIQIPYYDRRNKDEWIQKQKIESPWAVLAGDAVVFILASTAIRNLADPETILQMYDSMFKEEFHLRGTSFPFSRRGIVSSDIQIGVGYMHSGYPIGTQIYHNNNPYKSGYFFNKEILKKDGAWGLMHEMGHNLQEGTFTFNGTGETTTNIFSIIATESMTNQNSWSQTSGWFHERLTIERVQKYLISGTFDNNWRENHFVALCIYAQIKNYFGWEFYAQVFRRYNALTHKQRSISEDEKIQLWIKITSEISGMNLCPLYELWKWPITNQTEQELSKLPMFLPDDFVTKSVEKRIKEIICKRGSIFRQPLPVPVKVGPVKNKFTVEGAKIIE IQILN
Sbjct: 1 MGKVDFVKSGQRCIVWKNEYVNQILMDDTFVFDNTSIIGNNYCRNPTNFPNGLWCIIDEMTLEWEHCNIIKCIKDRNWCKDSDKGTEYLGDISHTKSGKLCQPWINFGTHRAYSFPERNLKFAGNKCRNPDMSKVPWCYYSNNYQREDCNVPRCDKEINQPEFFGTYDYLRGLGSNKTIVKLDDIYQTVNVTLSIKLESLKSRTLNKSSMWATAYNVECQSDLDEYEYCSITSSTNTSQDYIITYLCSGPLKYLMFISLLQKSDFTIKHAGAKYPKPSPSKQFNEYEKKMKEYYQNKNKNKFNLTLGEYPGYFYLLKDNAIAYAMNAKNKISMTLSTVGKGRIAFMGSDDLINVKPYKILLDFFQDVFDKPVESPTLLNKSYLQEIISKNKSQSVLSEPFIWNAEQVFGQDLVKVLLEYIKSGLRIIIGFESWSYIDKIKPLLDSELKILFYAAGVWPSLKYVQDQFQPVTQHSIHTMSLDKKFEYAKINNVTMNDVLAAYREVFDDIYIERSLDKIDFDLMKKVINDLYTDYWPFIQSLTPCLNYAISKQSDKGFLKFFSYILLSEIGKDLIPPALSLYPGKFQSTNPPFVNIKMKLNLLYKYEVAPLGLYLYPRLKTPVKIIQSKSTRCYIYVNHHHFNIADKSEVTKWPVTYKYFTIERGKWETIQFPFGGLMSISCNENNDKVEIIFKNVIQIPYYDRRNKDEWIQKQKIESPWAVLAGDAVVFILASTAIRNLADPETILQMYDSMFKEEFHLRGTSFPFSRRGIVSSDIQIGVGYMHSGYPIGTQIYHNNNPYKSGYFFNKEILKKDGAWGLMHEMGHNLQEGTFTFNGTGETTTNIFSIIATESMTNQNSWSQTSGWFHERLTIERVQKYLISGTFDNNWRENHFVALCIYAQIKNYFGWEFYAQVFRRYNALTHKQRSISEDEKIQLWIKITSEISGMNLCPLYELWKWPITNQTEQELSKLPMFLPDDFVTKSVEKRIKEIICKRGSIFRQPLPVPVKVGPVKNKFTVEGAKIIEHIQILN 1030
BLAST of Peptidase M60 domain-containing protein vs. Planmine SMEST
Match: SMESG000026376.1 (SMESG000026376.1) HSP 1 Score: 1909.81 bits (4946), Expect = 0.000e+0 Identity = 947/1069 (88.59%), Postives = 996/1069 (93.17%), Query Frame = 2
Query: 8 MLSAQLSVIFSLQYVIFAGYFEEIEKCRMTTHGREYMGKVDFVKSGQRCIVWKNEYVNQILMDDTFVFDNTSIIGNNYCRNPTNFPNGLWCIIDEMTLEWEHCNIIKCIKDRNWCKDSDKGTEYLGDISHTKSGKLCQPWINFGTHRAYSFPERNLKFAGNKCRNPDMSKVPWCYYSNNYQREDCNVPRCDKEINQPEFFGTYDYLRGLGSNKTIVKLDDIYQTVNVTLSIKLESLKSRTLNKSSMWATAYNVECQSDLDEYEYCSITSSTNTSQDYIITYLCSGPLKYLMFISLLQKSDFTIKHAGAKYPKPSPSKQFNEYEKKMKEYYQNKNKNKFNLTLGEYPGYFYLLKDNAIAYAMNAKNKISMTLSTVGKGRIAFMGSDDLINVKPYKILLDFFQDVFDKPVESPTLLNKSYLQEIISKNKSQSVLSEPFIWNAEQVFGQDLVKVLLEYIKSGLRIIIGFESWSYIDKIKPLLDSELKILFYAAGVWPSLKYVQDQFQPVTQHSIHTMSLDKKFEYAKINNVTMNDVLAAYREVFDDIYIERSLDKKDFDSMKKVIHDLYTDYWPFIQSLTPCLNYAISKQSDKGFLKFFSYILLSEIGKDLIPPALSLYPGKFQSTNPPFVNIKMKLNLLYKYEVAPLGLYLYPRLKTPVKIIQSKSTRCYIYVNHHHFNIADKSEVTKWPVTYKYFTIERGKWETIQFPFGGLMSISCNENNDKVEIIFKNVIQIPYYDRRNKD---EWIQKQKIESPWAVLAGDAVVFILASTAIRNLADPETILQMYDSMFKEEFHLRGTSFPFSRRGIVSSDIQIGVGYMHSGYPIGTQIYHNNNPYKSGYFFNKEILKKDGAWGLMHEMGHNLQXXXXXXXXXXXXXXXIFSIIATESMTNQNSWSQTSGWFHERLTIERVQKYLISGTFDNNWRENHFVALCIYAQIKNYFGWEFYAQVFRRYNALTHKQRSISEDEKIQLWIKITSEISGMNLCPLYELWKWPITNQTEQELSKLPMFLPDDFVTKSVEKRIKEIICKRGSIFRQXXXXXXXXXXXXXXFTVEGAKIIEQIQILN 3205
ML QLS IF LQ VIFAGYFEEIEKC+++THG EYMGKV++ KSGQRCI WKNEYVNQILMDDTFVFDNTSIIGNNYCRNPTNFPNG WCIIDEMTLEWEHCNIIKC+KDRNWCKDSDKGTEYLGDISHTKSGK+C+PWINF H A SFPE N+ AGNKCRNPDMSKVPWCYYSNNYQREDCNV RCD+ INQPE+FGTYDYLRGLGS+KTIVKLDDIY TV VTLSIKLESLKSRTLNKSSMWATAYNVECQSDLDEYE+CS+ T TS+DYIITYLCSGPLKYLMFISLLQKSDFTIKH G KYPKPSPSKQFNEY+KKMKEYYQNKNK + +L YPGYFYLLKDNAIAYA+NA NKISMT+STVGKGRI FM +D IN+ YK LL++FQDVFDKPV P LL KSYLQEIIS+NKS SVLSEPFIWNA Q FGQ LV VLLEYIKSGLRIIIGF+ WSY +KP+LDSE+KILFYAAG+WPSL Y++D+F+PVTQHSI+TMSLDKKFEYAKIN MNDVLAAYREVFDDIYIERSLDKKDFDSMKKVIHDLYTDYWPFIQSLTPCLNYAISKQSDKGFLKFFSYILLSEIGKDLIPPAL+LYPGKFQSTNPPFVNIKMKLNLLYKYEVAPLGLYLYPRLKT VKIIQSKSTRCYIYVNHHHFNIADKSEVTKWPVTYKYFTI+RGKWETIQFPFGGLMSISC+ENNDKVEIIFKNVIQIPYYDRRNK+ +WI+KQKIESPWAVLAGDAV+FILASTAIRNLADPETILQMYDSMFKEEFHLRGTSFP SRRGIVSSDIQIG GYMHSGYPIGTQIY+NNNPYKSGYFFNKEILKKDGAWGLMHEMGHNLQEGTFTFNGTGETTTNIFSIIATESMTNQNSWSQTSGWFHERLTIE VQ+YLI+GTFDNNWRENHFVALCIYAQIKNYFGWEFYAQVFRRYNALTHKQRSISEDEKIQLWIKITSEIS MNLCPLYELWKWPI++ TEQELSK PMFLPDDFVTKSVEKR II +RGS+ RQPLPVPVKVGPVKNKFTVEGAKIIE IQILN
Sbjct: 1 MLIVQLSAIFYLQCVIFAGYFEEIEKCKISTHGGEYMGKVNYGKSGQRCIFWKNEYVNQILMDDTFVFDNTSIIGNNYCRNPTNFPNGPWCIIDEMTLEWEHCNIIKCVKDRNWCKDSDKGTEYLGDISHTKSGKMCKPWINFRKHTANSFPENNVHLAGNKCRNPDMSKVPWCYYSNNYQREDCNVSRCDEAINQPEYFGTYDYLRGLGSSKTIVKLDDIYHTVTVTLSIKLESLKSRTLNKSSMWATAYNVECQSDLDEYEFCSVKKLTKTSEDYIITYLCSGPLKYLMFISLLQKSDFTIKHVGTKYPKPSPSKQFNEYDKKMKEYYQNKNKKEVTFSLARYPGYFYLLKDNAIAYAVNANNKISMTISTVGKGRIGFMAGEDSINLGSYKNLLNYFQDVFDKPVVKPKLLRKSYLQEIISENKSLSVLSEPFIWNAHQTFGQGLVNVLLEYIKSGLRIIIGFKPWSYESYVKPILDSEIKILFYAAGIWPSLHYIEDKFKPVTQHSIYTMSLDKKFEYAKINIKNMNDVLAAYREVFDDIYIERSLDKKDFDSMKKVIHDLYTDYWPFIQSLTPCLNYAISKQSDKGFLKFFSYILLSEIGKDLIPPALALYPGKFQSTNPPFVNIKMKLNLLYKYEVAPLGLYLYPRLKTSVKIIQSKSTRCYIYVNHHHFNIADKSEVTKWPVTYKYFTIKRGKWETIQFPFGGLMSISCDENNDKVEIIFKNVIQIPYYDRRNKENSKDWIRKQKIESPWAVLAGDAVIFILASTAIRNLADPETILQMYDSMFKEEFHLRGTSFPLSRRGIVSSDIQIGAGYMHSGYPIGTQIYYNNNPYKSGYFFNKEILKKDGAWGLMHEMGHNLQEGTFTFNGTGETTTNIFSIIATESMTNQNSWSQTSGWFHERLTIESVQEYLINGTFDNNWRENHFVALCIYAQIKNYFGWEFYAQVFRRYNALTHKQRSISEDEKIQLWIKITSEISKMNLCPLYELWKWPISDATEQELSKFPMFLPDDFVTKSVEKRTNNIIRRRGSVIRQPLPVPVKVGPVKNKFTVEGAKIIEHIQILN 1069
BLAST of Peptidase M60 domain-containing protein vs. Planmine SMEST
Match: SMESG000026362.1 (SMESG000026362.1) HSP 1 Score: 1776.14 bits (4599), Expect = 0.000e+0 Identity = 871/1069 (81.48%), Postives = 956/1069 (89.43%), Query Frame = 2
Query: 8 MLSAQLSVIFSLQYVIFAGYFEEIEKCRMTTHGREYMGKVDFVKSGQRCIVWKNEYVNQILMDDTFVFDNTSIIGNNYCRNPTNFPNGLWCIIDEMTLEWEHCNIIKCIKDRNWCKDSDKGTEYLGDISHTKSGKLCQPWINFGTHRAYSFPERNLKFAGNKCRNPDMSKVPWCYYSNNYQREDCNVPRCDKEINQPEFFGTYDYLRGLGSNKTIVKLDDIYQTVNVTLSIKLESLKSRTLNKSSMWATAYNVECQSDLDEYEYCSITSSTNTSQDYIITYLCSGPLKYLMFISLLQKSDFTIKHAGAKYPKPSPSKQFNEYEKKMKEYYQNKNKNKFNLTLGEYPGYFYLLKDNAIAYAMNAKNKISMTLSTVGKGRIAFMGSDDLINVKPYKILLDFFQDVFDKPVESPTLLNKSYLQEIISKNKSQSVLSEPFIWNAEQVFGQDLVKVLLEYIKSGLRIIIGFESWSYIDKIKPLLDSELKILFYAAGVWPSLKYVQDQFQPVTQHSIHTMSLDKKFEYAKINNVTMNDVLAAYREVFDDIYIERSLDKKDFDSMKKVIHDLYTDYWPFIQSLTPCLNYAISKQSDKGFLKFFSYILLSEIGKDLIPPALSLYPGKFQSTNPPFVNIKMKLNLLYKYEVAPLGLYLYPRLKTPVKIIQSKSTRCYIYVNHHHFNIADKSEVTKWPVTYKYFTIERGKWETIQFPFGGLMSISCNENNDKVEIIFKNVIQIPYYDRRNKD---EWIQKQKIESPWAVLAGDAVVFILASTAIRNLADPETILQMYDSMFKEEFHLRGTSFPFSRRGIVSSDIQIGVGYMHSGYPIGTQIYHNNNPYKSGYFFNKEILKKDGAWGLMHEMGHNLQXXXXXXXXXXXXXXXIFSIIATESMTNQNSWSQTSGWFHERLTIERVQKYLISGTFDNNWRENHFVALCIYAQIKNYFGWEFYAQVFRRYNALTHKQRSISEDEKIQLWIKITSEISGMNLCPLYELWKWPITNQTEQELSKLPMFLPDDFVTKSVEKRIKEIICKRGSIFRQXXXXXXXXXXXXXXFTVEGAKIIEQIQILN 3205
ML QLSVIFSLQYV FAGYFEEIEKCRMTTHG EYMGKV+F KSGQRCI WKNEYVN I+MDDTFVF NTSIIGNNYCRNPTNFP G WCIIDE+TLEWEHCNIIKCIKDRNWCKDSDKGTEYLGDISHTKSGK+C+PWINF H A SFPE N+ AGNKCRNPDMSKVPWCYYSNNYQREDCNVPRCD+ INQPE+FGTY+YL+G+ + KTIVKLDDIY TV VTLSIKLESLKSRTLNKSSMWATAYNVECQSDLDEYE+CS+ T TS+DYIITYLCSGPLKYLMFISLLQKSDFTIKH G KYPKPSPSKQFNEY++KM EYYQ K+K + ++LG +PG+FYLLKDNAI YAMNA NKISMT+STVGKGRIAFMGS+DLIN KPYK LLDFFQDVFDKPVE+P LLNK YLQ+IIS+NKS+S+LS+PFIW+ ++ G LV +LLEYIKSGLRIIIGF+ WSY D +PL SEL ILF+AAGVWPSLKYVQD+FQPVTQHSI+TMSLDK+FEYAK NN MNDV +++VFDDI IERSLDK++FD MK IHDLY DYWPFIQSLTPCL +S QSD+ FLKFFSYILL+E GKDL+PPALSLYPGKFQSTNPP VNIKMKLNLLYK EVAPLGLYLYPR KTPVKIIQSKSTRCYIYVNHH F++ADKSEVTKWPVTYKYFTIERGKWETIQFPFGGLMSISCNENNDKVEIIFKNVIQIPYYDRRNK+ +WI+KQKI++PWAVLAGD +VF+++S AIRNLADPET+LQMYDSMFKEE HLRGTSFP SRR I++SDIQI GYMHSGYPIGTQI++NNNP++ GYFFNK++LKK+GAWGL+HE+GHNLQ FTF+GT ETT NIFSIIAT SMTN++SWS TSGWF ERLTIERVQ+YLISGTFD NWR NHFVALCIYAQ+ N FGWEFYAQVFRRYN L ++ IS+D IQLWIK TSEIS MNLCPLYELWKWPI+N E+ELSK PMFLPDDFVTKSVE RI +II KRGS+ RQPLPVPVKVGPVKNKFTVEGAKIIEQIQILN
Sbjct: 1 MLIVQLSVIFSLQYVTFAGYFEEIEKCRMTTHGGEYMGKVNFGKSGQRCIFWKNEYVNHIVMDDTFVFVNTSIIGNNYCRNPTNFPRGPWCIIDEITLEWEHCNIIKCIKDRNWCKDSDKGTEYLGDISHTKSGKMCKPWINFRKHTANSFPENNVHLAGNKCRNPDMSKVPWCYYSNNYQREDCNVPRCDRTINQPEYFGTYNYLKGIYNYKTIVKLDDIYHTVTVTLSIKLESLKSRTLNKSSMWATAYNVECQSDLDEYEFCSVKKLTKTSEDYIITYLCSGPLKYLMFISLLQKSDFTIKHVGTKYPKPSPSKQFNEYDRKMNEYYQKKSKKELQISLGRFPGHFYLLKDNAIVYAMNANNKISMTISTVGKGRIAFMGSEDLINAKPYKSLLDFFQDVFDKPVENPKLLNKYYLQKIISENKSESILSQPFIWSPYRLLGPKLVGILLEYIKSGLRIIIGFKPWSYDDDKRPLSSSELTILFHAAGVWPSLKYVQDKFQPVTQHSIYTMSLDKRFEYAKKNNEIMNDVTEMFQKVFDDISIERSLDKRNFDLMKNSIHDLYADYWPFIQSLTPCLEVPVSAQSDRYFLKFFSYILLTEFGKDLMPPALSLYPGKFQSTNPPVVNIKMKLNLLYKNEVAPLGLYLYPRHKTPVKIIQSKSTRCYIYVNHHQFHVADKSEVTKWPVTYKYFTIERGKWETIQFPFGGLMSISCNENNDKVEIIFKNVIQIPYYDRRNKENSKDWIRKQKIKAPWAVLAGDTMVFVISSIAIRNLADPETLLQMYDSMFKEELHLRGTSFPLSRRDILTSDIQIKAGYMHSGYPIGTQIFYNNNPHRPGYFFNKKLLKKEGAWGLVHELGHNLQHDIFTFSGTIETTNNIFSIIATVSMTNESSWSPTSGWFKERLTIERVQEYLISGTFDKNWRGNHFVALCIYAQLINNFGWEFYAQVFRRYNVLANELGGISDDAIIQLWIKTTSEISKMNLCPLYELWKWPISNTNEKELSKFPMFLPDDFVTKSVENRINDIIRKRGSVIRQPLPVPVKVGPVKNKFTVEGAKIIEQIQILN 1069
BLAST of Peptidase M60 domain-containing protein vs. Planmine SMEST
Match: SMESG000026355.1 (SMESG000026355.1) HSP 1 Score: 1219.14 bits (3153), Expect = 0.000e+0 Identity = 600/1057 (56.76%), Postives = 790/1057 (74.74%), Query Frame = 2
Query: 59 AGYFEEIEKCRMTTHGREYMGKVDFVKSGQRCIVWKNEYVNQILMDDTFVFDNTSIIGNNYCRNPTNFPNGLWCIIDEMTLEWEHCNIIKCIKDRNWCKDSDKGTEYLGDISHTKSGKLCQPWINFGTHRAYSFPERNLKFAGNKCRNPDMSKVPWCYYSNNYQREDCNVPRCDKEINQPEFFGTYDYLRGLGSNKTIVKLDDIYQTVNVTLSIKLESLKSRTLNKSSMWATAYNVECQSDLDEYEYCSITSSTNTSQDYIITYLCSGPLKYLMFISLLQKSDFTIKHAGAKYP-KPSPSKQFNEYEKKMKEYYQNKNKNKFNLTLGEYPGYFYLLKDNAIAYAMNAKNKISMTLSTVGKGRIAFMGSDDLINVKPYKILLDFFQDVFDKPVESPTLLNKSYLQEIISKNKSQSVLSEPFIWNAEQVFGQDLVKVLLEYIKSGLRIIIGFESWSYIDKIKPLLDSELKILFYAAGVWPSLKYVQDQFQPVTQHSIHTMSLDKKFEYAKINNVTMNDVLAAYREVFDDIYIERSLDKKDFDSMKKVIHDLYTDYWPFIQSLTPCLNYAISKQSDKGFLKFFSYILLSEIGKDLIPPALSLYPGKFQSTNPPFVNIKMKLNLLYKYEVAPLGLYLYPRLKTPVKIIQSKSTRCYIYVNHHHFNIADKSEVTKWPVTYKYFTIERGKWETIQFPFGGLMSISCNENNDKVEIIFKNVIQIPYYDRRNK---DEWIQKQKIESPWAVLAGDAVVFILASTAIRNLADPETILQMYDSMFKEEFHLRGTSFPFSRRGIVSSDIQIGVGYMHSGYPIGTQIYHNNNPY-KSGYFFNKEILKKDGAWGLMHEMGHNLQXXXXXXXXXXXXXXXIFSIIATESMTNQNSWSQTSGWFHERLTIERVQKYLISGTFDNNWRENHFVALCIYAQIKNYFGWEFYAQVFRRYNALTHKQRSISEDEKIQLWIKITSEISGMNLCPLYELWKWPITNQTEQELSKLPMFLPDDFVTKSVEKRIKEIICKRG---SIFRQXXXXXXXXXXXXXXFTVEGAKIIEQIQILN 3205
+ YF +IE C++TTHGRE++G+ K+GQ+CI WK E++N++ +D+ S+IGNNYCRNPTNFPNG WCIIDE TL+WE+CNI CIKDRNWCKD++ G EYLGD+++TKSGK C PWIN TH SFPE+NL GNKCRNPDMS+ PWCYYS +RE+C+VP+CDK+ +Q E+FG YD+L+ + TI+ LD+IYQ V T+SIKLESL S LNK+S+WAT YN +CQ+DLDEYEYC+I S + ++YII+Y C PL++LMFIS L+K+++TIK++G Y PS++F EYE K+ EY Q KNKN+ + + PG+F+L +NAIAYA NA N+I +T+STVGKGRIAF+ +D +++ + L D F DV++K VESPT L K YLQEIISKN +S L EPFIWNA G++LV LL+ + SGLRIIIG + W+Y+ K +LDSELKILF AAGVWPSL Y + ++ VT+HS++TM L ++ EYAK+N T+ +V A ++ I +E+ L + +F+ +++ I DLY++Y P I+ L PC ++ +S+K L+FF++IL S GK +I P LS YPGKF S + P +IKM+LNL+Y EVA LGLY PR+ VKI QSKS C I++N+HHF++++K E+ KWP TY F+IER K ET F FGGL+SISC+E+NDKVEI F NV++IP +DRRNK +WI KQ + SPWAV+A D +VF+L+S AIRNLADP + L+++D M KEEFHL G + SRR +VS+DIQIG GYMHSGYPIGT+I+ NP + YFF+ L DG WGLMHE+GHNLQE FTFNG GE T NIF+++A ESMTN++SWS T+GW E+L ++ + ++ +GTF NW+EN F+AL IYAQ +N FGWEF+AQVFRRYN L ++ +IS+++KIQLWIK TSEISGMNLCPLYELW+WPI+ +TE ELSKL MFLPDDF+TK VEKR+ EII K G S+ R PL +P K+GP+ N+F +EGA+IIE+IQILN
Sbjct: 18 SSYFTDIENCKITTHGREFIGRTSITKNGQQCITWKEEFINKLQAGKIINYDSKSLIGNNYCRNPTNFPNGPWCIIDENTLKWEYCNIKSCIKDRNWCKDTENGREYLGDVNYTKSGKDCNPWINQRTHPKDSFPEKNLNLVGNKCRNPDMSEGPWCYYSTENKREECDVPKCDKKFSQIEYFGGYDFLKLIPDQMTIISLDNIYQDVKATVSIKLESLNSDILNKTSLWATDYNPKCQTDLDEYEYCTIVESKSEDENYIISYSCLEPLRHLMFISPLKKTEYTIKYSGKLYKINWKPSERFTEYENKVNEYLQKKNKNELKIQSDQIPGHFFLFSNNAIAYATNADNQIPVTISTVGKGRIAFLAADGVVDSIYFPQLKDLFNDVYEKQVESPTYLTKEYLQEIISKNSHESALLEPFIWNAHNELGEELVGTLLQLVNSGLRIIIGVKPWAYVTYHKKILDSELKILFQAAGVWPSLIYADNNWKTVTKHSVYTMPLYQRLEYAKLNANTLQNVSGAIVDIISKIPVEKVLSEINFNLIRESIFDLYSNYLPLIKGLIPCWEVGLTDESNKSLLRFFNFILASPFGKRIIVPGLSFYPGKFHSNDIPLKDIKMRLNLIYHKEVAQLGLYAIPRVDISVKITQSKSQFCRIFINYHHFDVSEKPEMYKWPKTYVEFSIERNKVETFSFSFGGLLSISCDEDNDKVEITFNNVVEIPLFDRRNKKDIKDWIHKQTLVSPWAVVASDTLVFVLSSNAIRNLADPNSFLELFDVMVKEEFHLIGRTIASSRREMVSADIQIGAGYMHSGYPIGTKIFWVTNPANEKDYFFHMYNLNIDGEWGLMHEVGHNLQESIFTFNGVGEVTNNIFTLVAIESMTNKSSWSPTNGWVPEKLYVKDLVDHINNGTFQ-NWKENDFLALAIYAQQRNSFGWEFFAQVFRRYNVLKNELGNISDEDKIQLWIKTTSEISGMNLCPLYELWRWPISQKTENELSKLQMFLPDDFLTKMVEKRVDEIISKFGGAKSVLRTPLTIPEKIGPLTNRFAIEGAQIIEEIQILN 1073 The following BLAST results are available for this feature:
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 3
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 0
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Peptidase M60 domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Peptidase M60 domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 4
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 3
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Peptidase M60 domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30019854 ID=SMED30019854|Name=Peptidase M60 domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=3244bpback to top protein sequence of SMED30019854-orf-1 >SMED30019854-orf-1 ID=SMED30019854-orf-1|Name=SMED30019854-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1069bp IFMLSAQLSVIFSLQYVIFAGYFEEIEKCRMTTHGREYMGKVDFVKSGQRback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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