NK homeobox1-1

Overview
NameNK homeobox1-1
Smed IDSMED30019740
Length (bp)1267
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of NK homeobox1-1 (SMED30019740) t-SNE clustered cells

Violin plots show distribution of expression levels for NK homeobox1-1 (SMED30019740) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of NK homeobox1-1 (SMED30019740) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for NK homeobox1-1 (SMED30019740) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30019740

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 2

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
body wall musculatureSMED30019740h1SMcG0009835 dd_Smed_v4_19327_0_1dd_Smed_v4PMID:30471994
Scimone et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
circular muscle cellSMED30019740h1SMcG0009835 dd_Smed_v4_19327_0_1dd_Smed_v4PMID:30471994
Scimone et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of NK homeobox1-1 vs. Ensembl Human
Match: NKX1-1 (NK1 homeobox 1 [Source:HGNC Symbol;Acc:HGNC:24975])

HSP 1 Score: 135.961 bits (341), Expect = 3.410e-35
Identity = 61/72 (84.72%), Postives = 65/72 (90.28%), Query Frame = 1 
Query:  574 SEDSSMKPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQNPGLDV 789
            S+  S KPRRART+FTY+QLVALENKFK TRYLSVCERLNLA SL+LTETQVKIWFQNRRTKWKKQNPG D 
Sbjct:  252 SDSKSGKPRRARTAFTYEQLVALENKFKATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGADT 323
[Close]
BLAST of NK homeobox1-1 vs. Ensembl Human
Match: NKX1-2 (NK1 homeobox 2 [Source:HGNC Symbol;Acc:HGNC:31652])

HSP 1 Score: 132.494 bits (332), Expect = 8.168e-35
Identity = 59/70 (84.29%), Postives = 64/70 (91.43%), Query Frame = 1 
Query:  577 EDSSMKPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQNPGLD 786
            E +  KPRRART+FTY+QLVALENKF+ TRYLSVCERLNLA SL+LTETQVKIWFQNRRTKWKKQNPG D
Sbjct:  157 EPNCAKPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGAD 226
[Close]
BLAST of NK homeobox1-1 vs. Ensembl Human
Match: BARHL1 (BarH like homeobox 1 [Source:HGNC Symbol;Acc:HGNC:953])

HSP 1 Score: 90.8929 bits (224), Expect = 1.014e-19
Identity = 60/148 (40.54%), Postives = 79/148 (53.38%), Query Frame = 1 
Query:  523 SSTDKNNSSNEADDTEIS--EDSS----MKPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQNP-GLDVXXXXXXXXXXXXR-----YYDHSLMSNF---ANFLNNRSYQAIDSSLHNNLI 921
            +S+D      E  D EIS   DS      KPR+ART+FT  QL  LE  F+  +YLSV +R+ LA SLNLT+TQVK W+QNRRTKWK+Q   GL++ +      +         +Y  SL+SN    A     R   A   +L   L+
Sbjct:  148 ASSDSEYKVKEEGDREISSSRDSPPVRLKKPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPSPYFYPQSLVSNLDPGAALYLYRGPSAPPPALQRPLV 295
[Close]
BLAST of NK homeobox1-1 vs. Ensembl Human
Match: BARHL1 (BarH like homeobox 1 [Source:HGNC Symbol;Acc:HGNC:953])

HSP 1 Score: 90.8929 bits (224), Expect = 1.014e-19
Identity = 60/148 (40.54%), Postives = 79/148 (53.38%), Query Frame = 1 
Query:  523 SSTDKNNSSNEADDTEIS--EDSS----MKPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQNP-GLDVXXXXXXXXXXXXR-----YYDHSLMSNF---ANFLNNRSYQAIDSSLHNNLI 921
            +S+D      E  D EIS   DS      KPR+ART+FT  QL  LE  F+  +YLSV +R+ LA SLNLT+TQVK W+QNRRTKWK+Q   GL++ +      +         +Y  SL+SN    A     R   A   +L   L+
Sbjct:  148 ASSDSEYKVKEEGDREISSSRDSPPVRLKKPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPSPYFYPQSLVSNLDPGAALYLYRGPSAPPPALQRPLV 295
[Close]
BLAST of NK homeobox1-1 vs. Ensembl Human
Match: BARHL2 (BarH like homeobox 2 [Source:HGNC Symbol;Acc:HGNC:954])

HSP 1 Score: 86.6557 bits (213), Expect = 5.533e-18
Identity = 44/93 (47.31%), Postives = 61/93 (65.59%), Query Frame = 1 
Query:  514 DDLSSTDKNNSSNEADDTEISEDS------SMKPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQN 774
            +D  S  K + + E  D EI+         + KPR+ART+F+  QL  LE  F+  +YLSV +R++LA +LNLT+TQVK W+QNRRTKWK+Q 
Sbjct:  199 EDSQSDIKCHGTKEEGDREITSSRESPPVRAKKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQT 291
[Close]
BLAST of NK homeobox1-1 vs. Ensembl Celegans
Match: ceh-1 (Homeobox protein ceh-1 [Source:UniProtKB/Swiss-Prot;Acc:P53547])

HSP 1 Score: 122.865 bits (307), Expect = 3.916e-33
Identity = 61/99 (61.62%), Postives = 73/99 (73.74%), Query Frame = 1 
Query:  508 INDDLSSTDKNNSSNEADDTEISEDSS-----MKPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQNPGLDV 789
            + D LS  +K+++S+EA   +   D       +K RRART+FTY+QLVALENKFK +RYLSV ERLNLA  L L+ETQVKIWFQNRRTKWKK NPG D 
Sbjct:    6 VEDLLSEREKDSNSDEATHQKSPADGGKSSRKLKMRRARTAFTYEQLVALENKFKTSRYLSVVERLNLAIQLQLSETQVKIWFQNRRTKWKKHNPGQDA 104
[Close]
BLAST of NK homeobox1-1 vs. Ensembl Celegans
Match: ceh-30 (Homeobox protein ceh-30 [Source:UniProtKB/Swiss-Prot;Acc:Q22909])

HSP 1 Score: 84.7297 bits (208), Expect = 1.249e-18
Identity = 45/96 (46.88%), Postives = 63/96 (65.62%), Query Frame = 1 
Query:  505 AINDDLSSTDKNNSSNEADDTEISEDSSMKPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQ-NPGLDV 789
            +I  D S++ +  +S+   D   S  S  K R+ART FT  QL  LEN F+  +YLSV +R++LA  + LT+TQVK W+QNRRTKWK+Q   G+D+
Sbjct:   67 SIKSDFSTSPR--ASSPGGDRMGSPGSCKKSRKARTIFTDKQLQELENTFEKQKYLSVQDRMDLAHRMGLTDTQVKTWYQNRRTKWKRQATSGMDL 160
[Close]
BLAST of NK homeobox1-1 vs. Ensembl Celegans
Match: ceh-30 (Homeobox protein ceh-30 [Source:UniProtKB/Swiss-Prot;Acc:Q22909])

HSP 1 Score: 84.7297 bits (208), Expect = 1.249e-18
Identity = 45/96 (46.88%), Postives = 63/96 (65.62%), Query Frame = 1 
Query:  505 AINDDLSSTDKNNSSNEADDTEISEDSSMKPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQ-NPGLDV 789
            +I  D S++ +  +S+   D   S  S  K R+ART FT  QL  LEN F+  +YLSV +R++LA  + LT+TQVK W+QNRRTKWK+Q   G+D+
Sbjct:   67 SIKSDFSTSPR--ASSPGGDRMGSPGSCKKSRKARTIFTDKQLQELENTFEKQKYLSVQDRMDLAHRMGLTDTQVKTWYQNRRTKWKRQATSGMDL 160
[Close]
BLAST of NK homeobox1-1 vs. Ensembl Celegans
Match: ceh-31 (Homeobox protein ceh-31 [Source:UniProtKB/Swiss-Prot;Acc:Q22910])

HSP 1 Score: 81.2629 bits (199), Expect = 3.549e-17
Identity = 53/137 (38.69%), Postives = 76/137 (55.47%), Query Frame = 1 
Query:  583 SSMKPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQ-NPGLDVXXXXXXXXXXXX-----RYYDHSLMSNFANFL--NNRSYQAIDSSLHNNLIGPFPHSLPATTNGNNL 969
             S K R+ART FT  QL  LEN F+  +YLSV +R+ LA  + LT+TQVK W+QNRRTKWK+Q + G+D+        +         Y+ + L  N + F   NNR        + N+L+ P    +PA+ + N+L
Sbjct:   90 GSKKARKARTIFTDKQLQELENTFEKQKYLSVQDRMELAHRMGLTDTQVKTWYQNRRTKWKRQASVGMDLLHDAGNMAAVQQLLRTNPYWANYLSQNTSMFGASNNR-------PVFNSLVVPTSSMIPASNSQNSL 219
[Close]
BLAST of NK homeobox1-1 vs. Ensembl Celegans
Match: ceh-9 (Homeobox protein ceh-9 [Source:UniProtKB/Swiss-Prot;Acc:P56407])

HSP 1 Score: 77.7962 bits (190), Expect = 5.461e-17
Identity = 40/92 (43.48%), Postives = 61/92 (66.30%), Query Frame = 1 
Query:  496 ELNAINDDLSSTDKNNSS-NEADDTEISEDSSMKPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKK 768
            +L  +N ++    +  SS ++A ++ I +    K ++ART+F+  Q+  LE +F+  +YLS  +R  LA  L++TETQVKIWFQNRRTKWKK
Sbjct:   36 DLPTVNGEIDEFGRCKSSLDQAKESPIEKCQKTKRKKARTTFSGKQVFELEKQFEAKKYLSSSDRSELAKRLDVTETQVKIWFQNRRTKWKK 127
[Close]
BLAST of NK homeobox1-1 vs. Ensembl Fly
Match: slou (gene:FBgn0002941 transcript:FBtr0084123)

HSP 1 Score: 137.117 bits (344), Expect = 8.577e-35
Identity = 67/96 (69.79%), Postives = 74/96 (77.08%), Query Frame = 1 
Query:  508 INDDLSSTD--KNNSSNEADDTEISEDSSMKPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQNPGLDV 789
            I+D  S TD  K  S N    +        KPRRART+FTY+QLV+LENKFK TRYLSVCERLNLA SL+LTETQVKIWFQNRRTKWKKQNPG+DV
Sbjct:  514 IDDPSSETDSKKGGSRNGDGKSGGGGGGGSKPRRARTAFTYEQLVSLENKFKTTRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGMDV 609
[Close]
BLAST of NK homeobox1-1 vs. Ensembl Fly
Match: slou (gene:FBgn0002941 transcript:FBtr0330389)

HSP 1 Score: 136.346 bits (342), Expect = 1.694e-34
Identity = 67/96 (69.79%), Postives = 74/96 (77.08%), Query Frame = 1 
Query:  508 INDDLSSTD--KNNSSNEADDTEISEDSSMKPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQNPGLDV 789
            I+D  S TD  K  S N    +        KPRRART+FTY+QLV+LENKFK TRYLSVCERLNLA SL+LTETQVKIWFQNRRTKWKKQNPG+DV
Sbjct:  514 IDDPSSETDSKKGGSRNGDGKSGGGGGGGSKPRRARTAFTYEQLVSLENKFKTTRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGMDV 609
[Close]
BLAST of NK homeobox1-1 vs. Ensembl Fly
Match: CG11085 (gene:FBgn0030408 transcript:FBtr0073656)

HSP 1 Score: 90.1225 bits (222), Expect = 5.744e-20
Identity = 40/64 (62.50%), Postives = 51/64 (79.69%), Query Frame = 1 
Query:  583 SSMKPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQN 774
            S  KPRR RT+FT+ QL  LE KF+  +YLSV +R ++A +LNL+ETQVK W+QNRRTKWK+QN
Sbjct:  156 SGRKPRRRRTAFTHAQLAYLERKFRCQKYLSVADRSDVAETLNLSETQVKTWYQNRRTKWKRQN 219
[Close]
BLAST of NK homeobox1-1 vs. Ensembl Fly
Match: lms (gene:FBgn0034520 transcript:FBtr0342702)

HSP 1 Score: 80.8777 bits (198), Expect = 2.030e-16
Identity = 41/109 (37.61%), Postives = 60/109 (55.05%), Query Frame = 1 
Query:  445 LDNGTNESSENLQLKPDELNAINDDLSSTDKNNSSNEADDTEISEDSSMKPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQ 771
            LD+  ++   ++ L  D+ N + DD                        + +R RT+F+  Q+ ALE +F+  +YLSV +R  LA  L LTETQ+KIWFQNRRTKWK++
Sbjct:   60 LDDNMDDGKSDIDLASDDGNGLGDD------------------------RKKRPRTAFSAAQIKALETEFERGKYLSVAKRTALAKQLQLTETQIKIWFQNRRTKWKRK 144
[Close]
BLAST of NK homeobox1-1 vs. Ensembl Fly
Match: lms (gene:FBgn0034520 transcript:FBtr0342701)

HSP 1 Score: 80.8777 bits (198), Expect = 2.030e-16
Identity = 41/109 (37.61%), Postives = 60/109 (55.05%), Query Frame = 1 
Query:  445 LDNGTNESSENLQLKPDELNAINDDLSSTDKNNSSNEADDTEISEDSSMKPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQ 771
            LD+  ++   ++ L  D+ N + DD                        + +R RT+F+  Q+ ALE +F+  +YLSV +R  LA  L LTETQ+KIWFQNRRTKWK++
Sbjct:   60 LDDNMDDGKSDIDLASDDGNGLGDD------------------------RKKRPRTAFSAAQIKALETEFERGKYLSVAKRTALAKQLQLTETQIKIWFQNRRTKWKRK 144
[Close]
BLAST of NK homeobox1-1 vs. Ensembl Zebrafish
Match: nkx1.2la (NK1 transcription factor related 2-like,a [Source:ZFIN;Acc:ZDB-GENE-040615-1])

HSP 1 Score: 132.109 bits (331), Expect = 3.271e-35
Identity = 59/71 (83.10%), Postives = 66/71 (92.96%), Query Frame = 1 
Query:  574 SEDSSMKPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQNPGLD 786
            S+ S  KPRRART+FTY+QLVALENKF+ TRYLSVCERLNLA SL+LTETQVKIWFQNRRTKWKKQNPG++
Sbjct:  134 SDHSCAKPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGVE 204
[Close]
BLAST of NK homeobox1-1 vs. Ensembl Zebrafish
Match: nkx1.2lb (NK1 transcription factor related 2-like,b [Source:ZFIN;Acc:ZDB-GENE-040615-2])

HSP 1 Score: 133.65 bits (335), Expect = 4.509e-35
Identity = 69/117 (58.97%), Postives = 80/117 (68.38%), Query Frame = 1 
Query:  439 NQLDNGTNESSENLQLKPDELNAINDDLSSTDKNNSSNEADDTEISEDSSMKPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQNPGLDV 789
            N  + G +E  +++   PD         SS  +N+          S+  S KPRRART+FTY+QLVALENKFK TRYLSVCERLNLA SL+LTETQVKIWFQNRRTKWKKQNPG D 
Sbjct:  150 NDAEFGQHEDDDSISKSPD--GQQTQQSSSNGQNHQVKPKRKRSGSDSKSGKPRRARTAFTYEQLVALENKFKSTRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGADT 264
[Close]
BLAST of NK homeobox1-1 vs. Ensembl Zebrafish
Match: barhl2 (BarH-like homeobox 2 [Source:ZFIN;Acc:ZDB-GENE-050913-153])

HSP 1 Score: 95.9005 bits (237), Expect = 2.015e-21
Identity = 62/150 (41.33%), Postives = 86/150 (57.33%), Query Frame = 1 
Query:  343 AQYVPYLCSLLSDENLNRSKVCEAVNGIGAKINQLDNGTNESSENLQLKPDELNAINDDLSSTDKNNSSNEADDTEIS--EDS----SMKPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQN 774
            A   PY  S+ S  +  +++   A +GI  K+ Q +N         + K D+ + I  DL      N + E  D EIS   DS    S KPR+ART+F+  QL  LE  F+  +YLSV +R++LA +LNLT+TQVK W+QNRRTKWK+Q 
Sbjct:  131 AACAPYSTSVPSPHHSPKTESGTAPDGIRPKLEQDEN---------RSKLDKRDDIQSDLKCL---NGTKEEGDREISSSRDSPPVRSKKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQT 268
[Close]
BLAST of NK homeobox1-1 vs. Ensembl Zebrafish
Match: barhl2 (BarH-like homeobox 2 [Source:ZFIN;Acc:ZDB-GENE-050913-153])

HSP 1 Score: 95.9005 bits (237), Expect = 2.015e-21
Identity = 62/150 (41.33%), Postives = 86/150 (57.33%), Query Frame = 1 
Query:  343 AQYVPYLCSLLSDENLNRSKVCEAVNGIGAKINQLDNGTNESSENLQLKPDELNAINDDLSSTDKNNSSNEADDTEIS--EDS----SMKPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQN 774
            A   PY  S+ S  +  +++   A +GI  K+ Q +N         + K D+ + I  DL      N + E  D EIS   DS    S KPR+ART+F+  QL  LE  F+  +YLSV +R++LA +LNLT+TQVK W+QNRRTKWK+Q 
Sbjct:  131 AACAPYSTSVPSPHHSPKTESGTAPDGIRPKLEQDEN---------RSKLDKRDDIQSDLKCL---NGTKEEGDREISSSRDSPPVRSKKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQT 268
[Close]
BLAST of NK homeobox1-1 vs. Ensembl Zebrafish
Match: barhl2 (BarH-like homeobox 2 [Source:ZFIN;Acc:ZDB-GENE-050913-153])

HSP 1 Score: 95.9005 bits (237), Expect = 2.015e-21
Identity = 62/150 (41.33%), Postives = 86/150 (57.33%), Query Frame = 1 
Query:  343 AQYVPYLCSLLSDENLNRSKVCEAVNGIGAKINQLDNGTNESSENLQLKPDELNAINDDLSSTDKNNSSNEADDTEIS--EDS----SMKPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQN 774
            A   PY  S+ S  +  +++   A +GI  K+ Q +N         + K D+ + I  DL      N + E  D EIS   DS    S KPR+ART+F+  QL  LE  F+  +YLSV +R++LA +LNLT+TQVK W+QNRRTKWK+Q 
Sbjct:  131 AACAPYSTSVPSPHHSPKTESGTAPDGIRPKLEQDEN---------RSKLDKRDDIQSDLKCL---NGTKEEGDREISSSRDSPPVRSKKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQT 268
[Close]
BLAST of NK homeobox1-1 vs. Ensembl Xenopus
Match: rpgrip1 (RPGR interacting protein 1 [Source:Xenbase;Acc:XB-GENE-1007974])

HSP 1 Score: 135.576 bits (340), Expect = 4.145e-35
Identity = 61/72 (84.72%), Postives = 65/72 (90.28%), Query Frame = 1 
Query:  574 SEDSSMKPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQNPGLDV 789
            S+  S KPRRART+FTY+QLVALENKFK TRYLSVCERLNLA SL+LTETQVKIWFQNRRTKWKKQNPG D 
Sbjct:  250 SDSKSGKPRRARTAFTYEQLVALENKFKSTRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGADT 321
[Close]
BLAST of NK homeobox1-1 vs. Ensembl Xenopus
Match: pmp2 (peripheral myelin protein 2 [Source:Xenbase;Acc:XB-GENE-977969])

HSP 1 Score: 119.783 bits (299), Expect = 9.738e-31
Identity = 61/128 (47.66%), Postives = 78/128 (60.94%), Query Frame = 1 
Query:  430 AKINQLDNGTNESS------ENLQLKPD------ELNAINDDLSSTDKNNSSNEADDTEISEDSSMKPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQNP 777
            AK+ Q+  GT E          L L  D      E+ A        +        +   +   ++ KPRRART+FTY+QLVALE++F+ +RYLSVCERL+LA +L+LTETQVKIWFQNRRTKWKKQ P
Sbjct:   33 AKVQQVKEGTQEPGMKEKGDTGLTLPSDSMVSGPEIKAETSPGEPEELPEKEENQETQNVPSVTNCKPRRARTAFTYEQLVALESRFRSSRYLSVCERLSLALTLHLTETQVKIWFQNRRTKWKKQQP 160
[Close]
BLAST of NK homeobox1-1 vs. Ensembl Xenopus
Match: BARHL2 (BarH like homeobox 2 [Source:NCBI gene;Acc:100493839])

HSP 1 Score: 93.9745 bits (232), Expect = 1.252e-20
Identity = 50/119 (42.02%), Postives = 73/119 (61.34%), Query Frame = 1 
Query:  451 NGTNES-----SENLQLKPDELNAINDDLSSTDKNNSSNEADDTEISEDS------SMKPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQN 774
            NG++ES      + +Q    +   I +DL +  K + + E  D EI+         + KPR+ART+F+  QL  LE  F+  +YLSV +R++LA +LNLT+TQVK W+QNRRTKWK+Q 
Sbjct:  145 NGSSESFRPKLEQEMQDGKGKAEKIREDLHTDIKGHGTKEEGDREITSSRESPPVRAKKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQT 263
[Close]
BLAST of NK homeobox1-1 vs. Ensembl Xenopus
Match: BARHL2 (BarH like homeobox 2 [Source:NCBI gene;Acc:100493839])

HSP 1 Score: 93.9745 bits (232), Expect = 1.315e-20
Identity = 50/119 (42.02%), Postives = 73/119 (61.34%), Query Frame = 1 
Query:  451 NGTNES-----SENLQLKPDELNAINDDLSSTDKNNSSNEADDTEISEDS------SMKPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQN 774
            NG++ES      + +Q    +   I +DL +  K + + E  D EI+         + KPR+ART+F+  QL  LE  F+  +YLSV +R++LA +LNLT+TQVK W+QNRRTKWK+Q 
Sbjct:  152 NGSSESFRPKLEQEMQDGKGKAEKIREDLHTDIKGHGTKEEGDREITSSRESPPVRAKKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQT 270
[Close]
BLAST of NK homeobox1-1 vs. Ensembl Xenopus
Match: pdlim7 (PDZ and LIM domain 7 [Source:Xenbase;Acc:XB-GENE-5860425])

HSP 1 Score: 87.4261 bits (215), Expect = 1.476e-18
Identity = 62/168 (36.90%), Postives = 82/168 (48.81%), Query Frame = 1 
Query:  550 NEADDTEIS--EDSS----MKPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQNP-GLDVXXXXXXXXXXXXRYYDHSLMSNFANFLNNRSYQAIDSSLHNNLIGPFPHSLPATTNGNNLPNHYFFNHQFPTNPPENSRYP 1032
             E  D EIS   DS      KPR+ART+FT  QL  LE  F+  +YLSV +R+ LA SLNLT+TQVK W+QNRRTKWK+Q   GL+                   L++   N+          S+L      P P+  P +   N  P    + ++ PT PP   + P
Sbjct:  157 KEEGDREISSSRDSPPVRLKKPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAVGLE-------------------LLAEAGNY----------SALQRMF--PSPYFYPQSLVSNLDPGAALYLYRGPTAPPPALQRP 293
[Close]
BLAST of NK homeobox1-1 vs. Ensembl Mouse
Match: Nkx1-2 (NK1 homeobox 2 [Source:MGI Symbol;Acc:MGI:104806])

HSP 1 Score: 135.576 bits (340), Expect = 3.833e-36
Identity = 60/71 (84.51%), Postives = 65/71 (91.55%), Query Frame = 1 
Query:  574 SEDSSMKPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQNPGLD 786
            +E S  KPRRART+FTY+QLVALENKF+ TRYLSVCERLNLA SL+LTETQVKIWFQNRRTKWKKQNPG D
Sbjct:  149 AESSCAKPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGAD 219
[Close]
BLAST of NK homeobox1-1 vs. Ensembl Mouse
Match: Nkx1-1 (NK1 homeobox 1 [Source:MGI Symbol;Acc:MGI:109346])

HSP 1 Score: 137.887 bits (346), Expect = 3.966e-36
Identity = 61/72 (84.72%), Postives = 65/72 (90.28%), Query Frame = 1 
Query:  574 SEDSSMKPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQNPGLDV 789
            S+  S KPRRART+FTY+QLVALENKFK TRYLSVCERLNLA SL+LTETQVKIWFQNRRTKWKKQNPG D 
Sbjct:  243 SDSKSGKPRRARTAFTYEQLVALENKFKATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGADT 314
[Close]
BLAST of NK homeobox1-1 vs. Ensembl Mouse
Match: Barhl1 (BarH like homeobox 1 [Source:MGI Symbol;Acc:MGI:1859288])

HSP 1 Score: 88.1965 bits (217), Expect = 6.563e-19
Identity = 58/139 (41.73%), Postives = 75/139 (53.96%), Query Frame = 1 
Query:  550 NEADDTEIS--EDSS----MKPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQNP-GLDVXXXXXXXXXXXXR-----YYDHSLMSNF---ANFLNNRSYQAIDSSLHNNLI 921
             E  D EIS   DS      KPR+ART+FT  QL  LE  F+  +YLSV +R+ LA SLNLT+TQVK W+QNRRTKWK+Q   GL++ +      +         +Y  SL+SN    A     R   A   +L   L+
Sbjct:  157 KEEGDREISSSRDSPPVRLKKPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPSPYFYPQSLVSNLDPGAALYLYRGPSAPPPALQRPLV 295
[Close]
BLAST of NK homeobox1-1 vs. Ensembl Mouse
Match: Barhl1 (BarH like homeobox 1 [Source:MGI Symbol;Acc:MGI:1859288])

HSP 1 Score: 88.1965 bits (217), Expect = 6.563e-19
Identity = 58/139 (41.73%), Postives = 75/139 (53.96%), Query Frame = 1 
Query:  550 NEADDTEIS--EDSS----MKPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQNP-GLDVXXXXXXXXXXXXR-----YYDHSLMSNF---ANFLNNRSYQAIDSSLHNNLI 921
             E  D EIS   DS      KPR+ART+FT  QL  LE  F+  +YLSV +R+ LA SLNLT+TQVK W+QNRRTKWK+Q   GL++ +      +         +Y  SL+SN    A     R   A   +L   L+
Sbjct:  157 KEEGDREISSSRDSPPVRLKKPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPSPYFYPQSLVSNLDPGAALYLYRGPSAPPPALQRPLV 295
[Close]
BLAST of NK homeobox1-1 vs. Ensembl Mouse
Match: Barhl1 (BarH like homeobox 1 [Source:MGI Symbol;Acc:MGI:1859288])

HSP 1 Score: 88.1965 bits (217), Expect = 6.563e-19
Identity = 58/139 (41.73%), Postives = 75/139 (53.96%), Query Frame = 1 
Query:  550 NEADDTEIS--EDSS----MKPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQNP-GLDVXXXXXXXXXXXXR-----YYDHSLMSNF---ANFLNNRSYQAIDSSLHNNLI 921
             E  D EIS   DS      KPR+ART+FT  QL  LE  F+  +YLSV +R+ LA SLNLT+TQVK W+QNRRTKWK+Q   GL++ +      +         +Y  SL+SN    A     R   A   +L   L+
Sbjct:  157 KEEGDREISSSRDSPPVRLKKPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPSPYFYPQSLVSNLDPGAALYLYRGPSAPPPALQRPLV 295
[Close]
BLAST of NK homeobox1-1 vs. UniProt/SwissProt
Match: sp|P42580|NKX12_MOUSE (NK1 transcription factor-related protein 2 OS=Mus musculus OX=10090 GN=Nkx1-2 PE=1 SV=1)

HSP 1 Score: 135.576 bits (340), Expect = 2.681e-35
Identity = 60/71 (84.51%), Postives = 65/71 (91.55%), Query Frame = 1 
Query:  574 SEDSSMKPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQNPGLD 786
            +E S  KPRRART+FTY+QLVALENKF+ TRYLSVCERLNLA SL+LTETQVKIWFQNRRTKWKKQNPG D
Sbjct:  149 AESSCAKPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGAD 219
[Close]
BLAST of NK homeobox1-1 vs. UniProt/SwissProt
Match: sp|Q15270|NKX11_HUMAN (NK1 transcription factor-related protein 1 OS=Homo sapiens OX=9606 GN=NKX1-1 PE=2 SV=2)

HSP 1 Score: 135.961 bits (341), Expect = 1.638e-34
Identity = 61/72 (84.72%), Postives = 65/72 (90.28%), Query Frame = 1 
Query:  574 SEDSSMKPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQNPGLDV 789
            S+  S KPRRART+FTY+QLVALENKFK TRYLSVCERLNLA SL+LTETQVKIWFQNRRTKWKKQNPG D 
Sbjct:  252 SDSKSGKPRRARTAFTYEQLVALENKFKATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGADT 323
[Close]
BLAST of NK homeobox1-1 vs. UniProt/SwissProt
Match: sp|Q9UD57|NKX12_HUMAN (NK1 transcription factor-related protein 2 OS=Homo sapiens OX=9606 GN=NKX1-2 PE=2 SV=3)

HSP 1 Score: 132.494 bits (332), Expect = 3.922e-34
Identity = 59/70 (84.29%), Postives = 64/70 (91.43%), Query Frame = 1 
Query:  577 EDSSMKPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQNPGLD 786
            E +  KPRRART+FTY+QLVALENKF+ TRYLSVCERLNLA SL+LTETQVKIWFQNRRTKWKKQNPG D
Sbjct:  157 EPNCAKPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGAD 226
[Close]
BLAST of NK homeobox1-1 vs. UniProt/SwissProt
Match: sp|P22807|SLOU_DROME (Homeobox protein slou OS=Drosophila melanogaster OX=7227 GN=slou PE=2 SV=1)

HSP 1 Score: 137.117 bits (344), Expect = 8.598e-34
Identity = 67/96 (69.79%), Postives = 74/96 (77.08%), Query Frame = 1 
Query:  508 INDDLSSTD--KNNSSNEADDTEISEDSSMKPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQNPGLDV 789
            I+D  S TD  K  S N    +        KPRRART+FTY+QLV+LENKFK TRYLSVCERLNLA SL+LTETQVKIWFQNRRTKWKKQNPG+DV
Sbjct:  514 IDDPSSETDSKKGGSRNGDGKSGGGGGGGSKPRRARTAFTYEQLVSLENKFKTTRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGMDV 609
[Close]
BLAST of NK homeobox1-1 vs. UniProt/SwissProt
Match: sp|P19601|SAX1_CHICK (Homeobox protein SAX-1 (Fragment) OS=Gallus gallus OX=9031 GN=SAX1 PE=2 SV=2)

HSP 1 Score: 125.176 bits (313), Expect = 3.932e-32
Identity = 56/67 (83.58%), Postives = 62/67 (92.54%), Query Frame = 1 
Query:  574 SEDSSMKPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQN 774
            +E S  KPRRART+FTY+QLVALENKF+ TRYLSVCERLNLA SL+LTETQVKIWFQNRRTKWKKQ+
Sbjct:   58 AEASCAKPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQH 124
[Close]
BLAST of NK homeobox1-1 vs. TrEMBL
Match: A0A291FGK3 (NK homeobox1-1 (Fragment) OS=Schmidtea mediterranea OX=79327 GN=nkx1-1 PE=2 SV=1)

HSP 1 Score: 260.381 bits (664), Expect = 3.670e-83
Identity = 137/137 (100.00%), Postives = 137/137 (100.00%), Query Frame = 1 
Query:  589 MKPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQNPGLDVXXXXXXXXXXXXRYYDHSLMSNFANFLNNRSYQAIDSSLHNNLIGPFPHSLPATTNGNNLPNHYFFNHQF 999
            MKPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQNPGLDVNSTTITPPSTNPRYYDHSLMSNFANFLNNRSYQAIDSSLHNNLIGPFPHSLPATTNGNNLPNHYFFNHQF
Sbjct:    1 MKPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQNPGLDVNSTTITPPSTNPRYYDHSLMSNFANFLNNRSYQAIDSSLHNNLIGPFPHSLPATTNGNNLPNHYFFNHQF 137
[Close]
BLAST of NK homeobox1-1 vs. TrEMBL
Match: A0A0L0CA57 (Homeobox protein slou OS=Lucilia cuprina OX=7375 GN=FF38_06299 PE=4 SV=1)

HSP 1 Score: 142.51 bits (358), Expect = 4.102e-37
Identity = 68/100 (68.00%), Postives = 77/100 (77.00%), Query Frame = 1 
Query:  493 DELNAINDDLSSTD-KNNSSNEADDTEISEDSSMKPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQNPGLDV 789
            D ++ I+D  S TD K   S   D    +     KPRRART+FTY+QLV+LENKFK TRYLSVCERLNLA SL+LTETQVKIWFQNRRTKWKKQNPG+DV
Sbjct:    9 DGMSDIDDHASETDSKKGGSRNGDGKSQNGGGGSKPRRARTAFTYEQLVSLENKFKTTRYLSVCERLNLAISLSLTETQVKIWFQNRRTKWKKQNPGMDV 108
[Close]
BLAST of NK homeobox1-1 vs. TrEMBL
Match: A0A182SFV6 (Homeobox domain-containing protein OS=Anopheles maculatus OX=74869 PE=4 SV=1)

HSP 1 Score: 142.51 bits (358), Expect = 4.218e-37
Identity = 69/96 (71.88%), Postives = 82/96 (85.42%), Query Frame = 1 
Query:  508 INDDLSSTD--KNNSSNEADDTEISEDSSMKPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQNPGLDV 789
            ++D  S TD  K+ S+N + D + S+ +S KPRRART+FTY+QLV+LENKFK TRYLSVCERLNLA SL+LTETQVKIWFQNRRTKWKKQNPG+DV
Sbjct:   10 MDDHASETDSKKDGSNNRSGDGK-SQGNSSKPRRARTAFTYEQLVSLENKFKTTRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGMDV 104
[Close]
BLAST of NK homeobox1-1 vs. TrEMBL
Match: A0A182UDN7 (Homeobox domain-containing protein OS=Anopheles melas OX=34690 PE=4 SV=1)

HSP 1 Score: 142.895 bits (359), Expect = 4.738e-37
Identity = 69/96 (71.88%), Postives = 82/96 (85.42%), Query Frame = 1 
Query:  508 INDDLSSTD--KNNSSNEADDTEISEDSSMKPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQNPGLDV 789
            ++D  S TD  K+ S+N + D + S+ +S KPRRART+FTY+QLV+LENKFK TRYLSVCERLNLA SL+LTETQVKIWFQNRRTKWKKQNPG+DV
Sbjct:   35 MDDHASETDSKKDGSNNRSGDGK-SQGNSSKPRRARTAFTYEQLVSLENKFKTTRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGMDV 129
[Close]
BLAST of NK homeobox1-1 vs. TrEMBL
Match: A0A182N164 (Homeobox domain-containing protein OS=Anopheles dirus OX=7168 PE=4 SV=1)

HSP 1 Score: 142.51 bits (358), Expect = 5.114e-37
Identity = 69/96 (71.88%), Postives = 83/96 (86.46%), Query Frame = 1 
Query:  508 INDDLSSTD--KNNSSNEADDTEISEDSSMKPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQNPGLDV 789
            ++D  S TD  K+ S+N + D++ S+ +S KPRRART+FTY+QLV+LENKFK TRYLSVCERLNLA SL+LTETQVKIWFQNRRTKWKKQNPG+DV
Sbjct:   22 MDDHASETDSKKDGSNNRSGDSK-SQGNSSKPRRARTAFTYEQLVSLENKFKTTRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGMDV 116
[Close]
BLAST of NK homeobox1-1 vs. Ensembl Cavefish
Match: nkx1.2lb (NK1 transcription factor related 2-like,b [Source:ZFIN;Acc:ZDB-GENE-040615-2])

HSP 1 Score: 134.806 bits (338), Expect = 1.477e-35
Identity = 61/72 (84.72%), Postives = 65/72 (90.28%), Query Frame = 1 
Query:  574 SEDSSMKPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQNPGLDV 789
            S+  S KPRRART+FTY+QLVALENKFK TRYLSVCERLNLA SL+LTETQVKIWFQNRRTKWKKQNPG D 
Sbjct:  185 SDSKSGKPRRARTAFTYEQLVALENKFKSTRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGADT 256
[Close]
BLAST of NK homeobox1-1 vs. Ensembl Cavefish
Match: nkx1.2la (NK1 transcription factor-related protein 2-like [Source:NCBI gene;Acc:103033039])

HSP 1 Score: 129.028 bits (323), Expect = 3.499e-34
Identity = 57/65 (87.69%), Postives = 62/65 (95.38%), Query Frame = 1 
Query:  592 KPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQNPGLD 786
            +PRRART+FTY+QLVALENKF+ TRYLSVCERLNLA SL+LTETQVKIWFQNRRTKWKKQNPG D
Sbjct:  135 RPRRARTAFTYEQLVALENKFRSTRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGAD 199
[Close]
BLAST of NK homeobox1-1 vs. Ensembl Cavefish
Match: pnx (homeobox protein CHOX-7-like [Source:NCBI gene;Acc:107197447])

HSP 1 Score: 85.8853 bits (211), Expect = 3.163e-19
Identity = 45/93 (48.39%), Postives = 58/93 (62.37%), Query Frame = 1 
Query:  502 NAINDDLSSTDKNNSSNEADDTEISEDSSMKPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQNPG 780
            ++IN + S  D ++ S        S   + K RR RT+FT +QL  LE  F+ + YLSV ER  +A +L L+ETQVKIWFQNRRTKWKK   G
Sbjct:   46 DSINGEESPADTDSLSAPDSPAPDSPVPTRKARRIRTAFTLEQLRVLERSFQSSHYLSVLERHVIASALRLSETQVKIWFQNRRTKWKKSREG 138
[Close]
BLAST of NK homeobox1-1 vs. Ensembl Cavefish
Match: ENSAMXT00000055685.1 (barH-like 1 homeobox protein [Source:NCBI gene;Acc:103037310])

HSP 1 Score: 87.4261 bits (215), Expect = 7.898e-19
Identity = 48/97 (49.48%), Postives = 64/97 (65.98%), Query Frame = 1 
Query:  499 LNAINDDLSSTDKNNSSNEAD-DTEISEDSSM----KPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQN 774
            L+ I+ + SS  +    +EA+ +   S DS      KPR+ART+FT  QL  LE  F+  +YLSV +R+ LA SLNLT+TQVK W+QNRRTKWK+Q 
Sbjct:  134 LDKIHSNSSSDSEYKVKDEAEREISSSRDSPQVRLKKPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQT 230
[Close]
BLAST of NK homeobox1-1 vs. Ensembl Cavefish
Match: barhl2 (BarH like homeobox 2 [Source:NCBI gene;Acc:103036087])

HSP 1 Score: 86.6557 bits (213), Expect = 2.359e-18
Identity = 48/98 (48.98%), Postives = 63/98 (64.29%), Query Frame = 1 
Query:  514 DDLSSTDKNNS-----SNEADDTEIS--EDS----SMKPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQN 774
            +DL    K N      + E  D EIS   DS    + KPR+ART+F+  QL  LE  F+  +YLSV +R++LA +LNLT+TQVK W+QNRRTKWK+Q 
Sbjct:  176 EDLQGEGKCNGEDLYGTKEEGDREISSSRDSPPVRTKKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQT 273
[Close]
BLAST of NK homeobox1-1 vs. Ensembl Sea Lamprey
Match: barhl2 (BarH-like homeobox 2 [Source:ZFIN;Acc:ZDB-GENE-050913-153])

HSP 1 Score: 79.7221 bits (195), Expect = 2.471e-18
Identity = 36/60 (60.00%), Postives = 48/60 (80.00%), Query Frame = 1 
Query:  592 KPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQ 771
            KPR+ART+F+  QL  LE  F+  +YLSV +R+ LA SL+L++TQVK W+QNRRTKWK+Q
Sbjct:    4 KPRKARTAFSDHQLTQLERSFERQKYLSVQDRMELASSLSLSDTQVKTWYQNRRTKWKRQ 63
[Close]
BLAST of NK homeobox1-1 vs. Ensembl Sea Lamprey
Match: barhl2 (BarH-like homeobox 2 [Source:ZFIN;Acc:ZDB-GENE-050913-153])

HSP 1 Score: 77.7962 bits (190), Expect = 7.892e-18
Identity = 36/60 (60.00%), Postives = 48/60 (80.00%), Query Frame = 1 
Query:  592 KPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQ 771
            KPR+ART+F+  QL  LE  F+  +YLSV +R+ LA SL+L++TQVK W+QNRRTKWK+Q
Sbjct:    4 KPRKARTAFSDHQLTQLERSFERQKYLSVQDRMELASSLSLSDTQVKTWYQNRRTKWKRQ 63
[Close]
BLAST of NK homeobox1-1 vs. Ensembl Sea Lamprey
Match: MSX1 (msh homeobox 1 [Source:HGNC Symbol;Acc:HGNC:7391])

HSP 1 Score: 77.411 bits (189), Expect = 2.165e-17
Identity = 35/57 (61.40%), Postives = 44/57 (77.19%), Query Frame = 1 
Query:  598 RRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKK 768
            R+ RT FT  QL+ALE+KF+  +YLS+ ER   + SL+LTETQVKIWFQNRR K K+
Sbjct:   15 RKPRTPFTTSQLLALEHKFRQKQYLSIAERAEFSTSLSLTETQVKIWFQNRRAKAKR 71
[Close]
BLAST of NK homeobox1-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001141.1 (pep scaffold:Pmarinus_7.0:GL478075:36995:38394:-1 gene:ENSPMAG00000001023.1 transcript:ENSPMAT00000001141.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 75.0998 bits (183), Expect = 4.012e-17
Identity = 36/63 (57.14%), Postives = 43/63 (68.25%), Query Frame = 1 
Query:  592 KPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQNPG 780
            K RR RT+F+  QL+ LE  F   RYLS  +R  +A +L LTETQVKIWFQNRR KWK+   G
Sbjct:    2 KCRRPRTAFSSQQLLELERHFSRQRYLSRPQRFQVASALMLTETQVKIWFQNRRMKWKRGKGG 64
[Close]
BLAST of NK homeobox1-1 vs. Ensembl Sea Lamprey
Match: HMX1 (H6 family homeobox 1 [Source:HGNC Symbol;Acc:HGNC:5017])

HSP 1 Score: 74.3294 bits (181), Expect = 1.576e-16
Identity = 35/58 (60.34%), Postives = 43/58 (74.14%), Query Frame = 1 
Query:  598 RRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQ 771
            ++ RT F+  Q+  LE+ F + RYLS  ER  LA SL+LTETQVKIWFQNRR KWK+Q
Sbjct:    2 KKTRTVFSRSQVFQLESTFDMKRYLSSAERAGLAASLHLTETQVKIWFQNRRNKWKRQ 59
[Close]
BLAST of NK homeobox1-1 vs. Ensembl Yeast
Match: PHO2 (Homeobox transcription factor; regulatory targets include genes involved in phosphate metabolism; binds cooperatively with Pho4p to the PHO5 promoter; phosphorylation of Pho2p facilitates interaction with Pho4p; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000002264])

HSP 1 Score: 46.9802 bits (110), Expect = 3.961e-6
Identity = 24/69 (34.78%), Postives = 38/69 (55.07%), Query Frame = 1 
Query:  574 SEDSSMKPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQNPG 780
            S+    +P+R R     + L  L+ KF+I    S+ ER  ++  + + E  V+IWFQNRR K +K+  G
Sbjct:   72 SDSGPQRPKRTRAK--GEALDVLKRKFEINPTPSLVERKKISDLIGMPEKNVRIWFQNRRAKLRKKQHG 138
[Close]
BLAST of NK homeobox1-1 vs. Ensembl Nematostella
Match: NK-1 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RI80])

HSP 1 Score: 137.117 bits (344), Expect = 1.681e-37
Identity = 69/113 (61.06%), Postives = 82/113 (72.57%), Query Frame = 1 
Query:  490 PDELNAINDDLSSTDKNNSSNEADD-------------TEISEDSSMKPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQNPGLDV 789
            PD+  A + D+S +D+  +    +D             TE +++   KPRRART+FTY+QLVALENKFK TRYLSVCERLNLA SL LTETQVKIWFQNRRTKWKKQNPG+DV
Sbjct:  111 PDKDKASDVDISRSDQETTDAAGEDPKSSSKSKRKRGSTERAKEG--KPRRARTAFTYEQLVALENKFKSTRYLSVCERLNLALSLGLTETQVKIWFQNRRTKWKKQNPGMDV 221
[Close]
BLAST of NK homeobox1-1 vs. Ensembl Nematostella
Match: EDO38891 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SBL6])

HSP 1 Score: 78.9518 bits (193), Expect = 1.795e-18
Identity = 39/65 (60.00%), Postives = 50/65 (76.92%), Query Frame = 1 
Query:  598 RRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQ-NPGLDV 789
            RR RT+FT  QL +LE KF+  +YL++ ER +LA S++LT TQVK WFQNRRTKWKKQ +P L+ 
Sbjct:    2 RRRRTAFTSSQLKSLEEKFQEKKYLTISERNSLAKSMHLTNTQVKTWFQNRRTKWKKQMSPDLEA 66
[Close]
BLAST of NK homeobox1-1 vs. Ensembl Nematostella
Match: EDO43402 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RYQ0])

HSP 1 Score: 77.7962 bits (190), Expect = 4.465e-18
Identity = 38/62 (61.29%), Postives = 46/62 (74.19%), Query Frame = 1 
Query:  586 SMKPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQ 771
            S K RR RT+FT  QL  LE KF+  +YL++ ER  LA S+ L++TQVK WFQNRRTKWKKQ
Sbjct:    8 SSKSRRKRTAFTSSQLKYLEEKFQEKKYLTISERNELAKSMYLSDTQVKTWFQNRRTKWKKQ 69
[Close]
BLAST of NK homeobox1-1 vs. Ensembl Nematostella
Match: EDO32495 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SUX2])

HSP 1 Score: 75.485 bits (184), Expect = 2.206e-17
Identity = 35/58 (60.34%), Postives = 48/58 (82.76%), Query Frame = 1 
Query:  598 RRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQ 771
            +R RT+FT +Q+  LE +F+ ++YLSV  R+ LA SL+LTETQ+KIWFQNRRTKWK++
Sbjct:    2 KRPRTAFTNEQIKDLEAEFQKSKYLSVSRRMELANSLSLTETQIKIWFQNRRTKWKRK 59
[Close]
BLAST of NK homeobox1-1 vs. Ensembl Nematostella
Match: EDO47164 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RMV1])

HSP 1 Score: 74.7146 bits (182), Expect = 4.522e-17
Identity = 36/61 (59.02%), Postives = 46/61 (75.41%), Query Frame = 1 
Query:  598 RRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQNPG 780
            RR RT+FT  QL  LE+KFK ++YL++ ER  +A SL LT  Q+K WFQNRRTKWK++N G
Sbjct:    1 RRKRTAFTSFQLKCLEDKFKFSKYLTIAERDMMARSLQLTNRQIKTWFQNRRTKWKRENVG 61
[Close]
BLAST of NK homeobox1-1 vs. Ensembl Medaka
Match: nkx1.2la (NK1 homeobox 2 [Source:NCBI gene;Acc:101168069])

HSP 1 Score: 132.109 bits (331), Expect = 2.725e-35
Identity = 59/71 (83.10%), Postives = 65/71 (91.55%), Query Frame = 1 
Query:  574 SEDSSMKPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQNPGLD 786
            S+ +  KPRRART+FTY+QLVALENKF+ TRYLSVCERLNLA SL+LTETQVKIWFQNRRTKWKKQNPG D
Sbjct:  123 SDQACAKPRRARTAFTYEQLVALENKFRTTRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGAD 193
[Close]
BLAST of NK homeobox1-1 vs. Ensembl Medaka
Match: nkx1.2lb (NK1 homeobox 1 [Source:NCBI gene;Acc:101166641])

HSP 1 Score: 135.191 bits (339), Expect = 2.998e-35
Identity = 61/72 (84.72%), Postives = 65/72 (90.28%), Query Frame = 1 
Query:  574 SEDSSMKPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQNPGLDV 789
            S+  S KPRRART+FTY+QLVALENKFK TRYLSVCERLNLA SL+LTETQVKIWFQNRRTKWKKQNPG D 
Sbjct:  246 SDSKSGKPRRARTAFTYEQLVALENKFKSTRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGADT 317
[Close]
BLAST of NK homeobox1-1 vs. Ensembl Medaka
Match: nkx1.2lb (NK1 homeobox 1 [Source:NCBI gene;Acc:101166641])

HSP 1 Score: 134.035 bits (336), Expect = 6.140e-35
Identity = 61/72 (84.72%), Postives = 65/72 (90.28%), Query Frame = 1 
Query:  574 SEDSSMKPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQNPGLDV 789
            S+  S KPRRART+FTY+QLVALENKFK TRYLSVCERLNLA SL+LTETQVKIWFQNRRTKWKKQNPG D 
Sbjct:  229 SDSKSGKPRRARTAFTYEQLVALENKFKSTRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGADT 300
[Close]
BLAST of NK homeobox1-1 vs. Ensembl Medaka
Match: barhl2 (BarH like homeobox 2 [Source:NCBI gene;Acc:101174414])

HSP 1 Score: 92.8189 bits (229), Expect = 1.685e-20
Identity = 49/93 (52.69%), Postives = 64/93 (68.82%), Query Frame = 1 
Query:  514 DDLSSTDKNNSSNEADDTEIS--EDS----SMKPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQN 774
            D++ S  K N + E  D EIS   DS    + KPR+ART+FT  QL  LE  F+  +YLSV +R++LA +LNLT+TQVK W+QNRRTKWK+Q 
Sbjct:  173 DEIPSEMKCNGTKEEGDREISSSRDSPPVRTKKPRKARTAFTDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQT 265
[Close]
BLAST of NK homeobox1-1 vs. Ensembl Medaka
Match: ENSORLT00000038356.1 (barH-like 1 homeobox protein [Source:NCBI gene;Acc:100049373])

HSP 1 Score: 91.2781 bits (225), Expect = 3.641e-20
Identity = 51/96 (53.12%), Postives = 63/96 (65.62%), Query Frame = 1 
Query:  523 SSTDKNNSSNEADDTEIS--EDSSM----KPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQNP-GLDV 789
            SS+D      E  D EIS   DS      KPR+ART+FT  QL  LE  F+  +YLSV +R+ LA SLNLT+TQVK W+QNRRTKWK+Q   GL++
Sbjct:  143 SSSDSEYKVKEEGDREISSSRDSPQVRLKKPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAVGLEL 238
[Close]
BLAST of NK homeobox1-1 vs. Planmine SMEST
Match: SMESG000051002.1 (SMESG000051002.1)

HSP 1 Score: 671.389 bits (1731), Expect = 0.000e+0
Identity = 344/344 (100.00%), Postives = 344/344 (100.00%), Query Frame = 1 
Query:  109 MRNFNSETLKEWVISKNTNSKSNDKPDRSEQRFSNNKPIHINNSFSIQALLDIPENSHKLQEIPQKIISSYTNGFRINAQYVPYLCSLLSDENLNRSKVCEAVNGIGAKINQLDNGTNESSENLQLKPDELNAINDDLSSTDKNNSSNEADDTEISEDSSMKPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQNPGLDVXXXXXXXXXXXXRYYDHSLMSNFANFLNNRSYQAIDSSLHNNLIGPFPHSLPATTNGNNLPNHYFFNHQFPTNPPENSRYPQFLKSRDSLKLIDHIRHSIKSSAISQNIPNSIHSLN 1140
            MRNFNSETLKEWVISKNTNSKSNDKPDRSEQRFSNNKPIHINNSFSIQALLDIPENSHKLQEIPQKIISSYTNGFRINAQYVPYLCSLLSDENLNRSKVCEAVNGIGAKINQLDNGTNESSENLQLKPDELNAINDDLSSTDKNNSSNEADDTEISEDSSMKPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQNPGLDVNSTTITPPSTNPRYYDHSLMSNFANFLNNRSYQAIDSSLHNNLIGPFPHSLPATTNGNNLPNHYFFNHQFPTNPPENSRYPQFLKSRDSLKLIDHIRHSIKSSAISQNIPNSIHSLN
Sbjct:    1 MRNFNSETLKEWVISKNTNSKSNDKPDRSEQRFSNNKPIHINNSFSIQALLDIPENSHKLQEIPQKIISSYTNGFRINAQYVPYLCSLLSDENLNRSKVCEAVNGIGAKINQLDNGTNESSENLQLKPDELNAINDDLSSTDKNNSSNEADDTEISEDSSMKPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQNPGLDVNSTTITPPSTNPRYYDHSLMSNFANFLNNRSYQAIDSSLHNNLIGPFPHSLPATTNGNNLPNHYFFNHQFPTNPPENSRYPQFLKSRDSLKLIDHIRHSIKSSAISQNIPNSIHSLN 344
[Close]
BLAST of NK homeobox1-1 vs. Planmine SMEST
Match: SMESG000041571.1 (SMESG000041571.1)

HSP 1 Score: 123.635 bits (309), Expect = 1.522e-32
Identity = 57/67 (85.07%), Postives = 61/67 (91.04%), Query Frame = 1 
Query:  589 MKPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQNPGLDV 789
            +K RRART+FTY+QLV+LENKFK TRYLSVCERLNLA SL LTE QVKIWFQNRRTKWKKQNPG DV
Sbjct:   61 LKSRRARTAFTYEQLVSLENKFKSTRYLSVCERLNLAHSLQLTEIQVKIWFQNRRTKWKKQNPGSDV 127
[Close]
BLAST of NK homeobox1-1 vs. Planmine SMEST
Match: SMESG000077917.1 (SMESG000077917.1)

HSP 1 Score: 114.775 bits (286), Expect = 2.649e-29
Identity = 60/66 (90.91%), Postives = 64/66 (96.97%), Query Frame = 1 
Query:  592 KPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQNPGLDV 789
            KPRRART+FTY+QLVALENKFK+TRYLSVCERLNLA +LNLTETQVKIWFQNRRTKWKKQNPG DV
Sbjct:   97 KPRRARTAFTYEQLVALENKFKVTRYLSVCERLNLALTLNLTETQVKIWFQNRRTKWKKQNPGQDV 162
[Close]
BLAST of NK homeobox1-1 vs. Planmine SMEST
Match: SMESG000021901.1 (SMESG000021901.1)

HSP 1 Score: 83.9593 bits (206), Expect = 4.969e-18
Identity = 49/112 (43.75%), Postives = 65/112 (58.04%), Query Frame = 1 
Query:  592 KPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQNPGLDVXXXXXXXXXXXXRYYDHSLMSNFANFLNNRSYQAIDSSLHNNLIGP 927
            K +++RT+F+  Q+  LE +F++ +YLS  ER  LA SLN+TETQVKIWFQNRRTKWKKQ     V +        N R  D  LMS   +  N    Q  D+ + N +  P
Sbjct:  146 KKKKSRTTFSGRQICELEKQFELKKYLSSAERAELASSLNVTETQVKIWFQNRRTKWKKQENITTVLAQQFRQSIDNNRSID--LMSELES--NGSENQYYDTKITNKITNP 253
[Close]
BLAST of NK homeobox1-1 vs. Planmine SMEST
Match: SMESG000022963.1 (SMESG000022963.1)

HSP 1 Score: 80.8777 bits (198), Expect = 2.122e-17
Identity = 40/70 (57.14%), Postives = 51/70 (72.86%), Query Frame = 1 
Query:  583 SSMKPRRARTSFTYDQLVALENKFKITRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQ-NPGLDV 789
            S  +PR+ART+FT  QL  LE  F   +YLSV +RL LA  L LT+TQVK W+QNRRTKWK+Q + G+D+
Sbjct:   62 SEKRPRKARTAFTEKQLCELEKSFDKHKYLSVQDRLELANYLELTDTQVKTWYQNRRTKWKRQTSTGVDL 131
The following BLAST results are available for this feature:
BLAST of NK homeobox1-1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
NKX1-13.410e-3584.72NK1 homeobox 1 [Source:HGNC Symbol;Acc:HGNC:24975][more]
NKX1-28.168e-3584.29NK1 homeobox 2 [Source:HGNC Symbol;Acc:HGNC:31652][more]
BARHL11.014e-1940.54BarH like homeobox 1 [Source:HGNC Symbol;Acc:HGNC:... [more]
BARHL11.014e-1940.54BarH like homeobox 1 [Source:HGNC Symbol;Acc:HGNC:... [more]
BARHL25.533e-1847.31BarH like homeobox 2 [Source:HGNC Symbol;Acc:HGNC:... [more]
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BLAST of NK homeobox1-1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ceh-13.916e-3361.62Homeobox protein ceh-1 [Source:UniProtKB/Swiss-Pr... [more]
ceh-301.249e-1846.88Homeobox protein ceh-30 [Source:UniProtKB/Swiss-P... [more]
ceh-301.249e-1846.88Homeobox protein ceh-30 [Source:UniProtKB/Swiss-P... [more]
ceh-313.549e-1738.69Homeobox protein ceh-31 [Source:UniProtKB/Swiss-P... [more]
ceh-95.461e-1743.48Homeobox protein ceh-9 [Source:UniProtKB/Swiss-Pr... [more]
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BLAST of NK homeobox1-1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
slou8.577e-3569.79gene:FBgn0002941 transcript:FBtr0084123[more]
slou1.694e-3469.79gene:FBgn0002941 transcript:FBtr0330389[more]
CG110855.744e-2062.50gene:FBgn0030408 transcript:FBtr0073656[more]
lms2.030e-1637.61gene:FBgn0034520 transcript:FBtr0342702[more]
lms2.030e-1637.61gene:FBgn0034520 transcript:FBtr0342701[more]
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BLAST of NK homeobox1-1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
nkx1.2la3.271e-3583.10NK1 transcription factor related 2-like,a [Source:... [more]
nkx1.2lb4.509e-3558.97NK1 transcription factor related 2-like,b [Source:... [more]
barhl22.015e-2141.33BarH-like homeobox 2 [Source:ZFIN;Acc:ZDB-GENE-050... [more]
barhl22.015e-2141.33BarH-like homeobox 2 [Source:ZFIN;Acc:ZDB-GENE-050... [more]
barhl22.015e-2141.33BarH-like homeobox 2 [Source:ZFIN;Acc:ZDB-GENE-050... [more]
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BLAST of NK homeobox1-1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rpgrip14.145e-3584.72RPGR interacting protein 1 [Source:Xenbase;Acc:XB-... [more]
pmp29.738e-3147.66peripheral myelin protein 2 [Source:Xenbase;Acc:XB... [more]
BARHL21.252e-2042.02BarH like homeobox 2 [Source:NCBI gene;Acc:1004938... [more]
BARHL21.315e-2042.02BarH like homeobox 2 [Source:NCBI gene;Acc:1004938... [more]
pdlim71.476e-1836.90PDZ and LIM domain 7 [Source:Xenbase;Acc:XB-GENE-5... [more]
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BLAST of NK homeobox1-1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Nkx1-23.833e-3684.51NK1 homeobox 2 [Source:MGI Symbol;Acc:MGI:104806][more]
Nkx1-13.966e-3684.72NK1 homeobox 1 [Source:MGI Symbol;Acc:MGI:109346][more]
Barhl16.563e-1941.73BarH like homeobox 1 [Source:MGI Symbol;Acc:MGI:18... [more]
Barhl16.563e-1941.73BarH like homeobox 1 [Source:MGI Symbol;Acc:MGI:18... [more]
Barhl16.563e-1941.73BarH like homeobox 1 [Source:MGI Symbol;Acc:MGI:18... [more]
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BLAST of NK homeobox1-1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P42580|NKX12_MOUSE2.681e-3584.51NK1 transcription factor-related protein 2 OS=Mus ... [more]
sp|Q15270|NKX11_HUMAN1.638e-3484.72NK1 transcription factor-related protein 1 OS=Homo... [more]
sp|Q9UD57|NKX12_HUMAN3.922e-3484.29NK1 transcription factor-related protein 2 OS=Homo... [more]
sp|P22807|SLOU_DROME8.598e-3469.79Homeobox protein slou OS=Drosophila melanogaster O... [more]
sp|P19601|SAX1_CHICK3.932e-3283.58Homeobox protein SAX-1 (Fragment) OS=Gallus gallus... [more]
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BLAST of NK homeobox1-1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A291FGK33.670e-83100.00NK homeobox1-1 (Fragment) OS=Schmidtea mediterrane... [more]
A0A0L0CA574.102e-3768.00Homeobox protein slou OS=Lucilia cuprina OX=7375 G... [more]
A0A182SFV64.218e-3771.88Homeobox domain-containing protein OS=Anopheles ma... [more]
A0A182UDN74.738e-3771.88Homeobox domain-containing protein OS=Anopheles me... [more]
A0A182N1645.114e-3771.88Homeobox domain-containing protein OS=Anopheles di... [more]
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BLAST of NK homeobox1-1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
nkx1.2lb1.477e-3584.72NK1 transcription factor related 2-like,b [Source:... [more]
nkx1.2la3.499e-3487.69NK1 transcription factor-related protein 2-like [S... [more]
pnx3.163e-1948.39homeobox protein CHOX-7-like [Source:NCBI gene;Acc... [more]
ENSAMXT00000055685.17.898e-1949.48barH-like 1 homeobox protein [Source:NCBI gene;Acc... [more]
barhl22.359e-1848.98BarH like homeobox 2 [Source:NCBI gene;Acc:1030360... [more]
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BLAST of NK homeobox1-1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
barhl22.471e-1860.00BarH-like homeobox 2 [Source:ZFIN;Acc:ZDB-GENE-050... [more]
barhl27.892e-1860.00BarH-like homeobox 2 [Source:ZFIN;Acc:ZDB-GENE-050... [more]
MSX12.165e-1761.40msh homeobox 1 [Source:HGNC Symbol;Acc:HGNC:7391][more]
ENSPMAT00000001141.14.012e-1757.14pep scaffold:Pmarinus_7.0:GL478075:36995:38394:-1 ... [more]
HMX11.576e-1660.34H6 family homeobox 1 [Source:HGNC Symbol;Acc:HGNC:... [more]
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BLAST of NK homeobox1-1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
PHO23.961e-634.78Homeobox transcription factor; regulatory targets ... [more]
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BLAST of NK homeobox1-1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
NK-11.681e-3761.06Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO388911.795e-1860.00Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO434024.465e-1861.29Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO324952.206e-1760.34Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO471644.522e-1759.02Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of NK homeobox1-1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
nkx1.2la2.725e-3583.10NK1 homeobox 2 [Source:NCBI gene;Acc:101168069][more]
nkx1.2lb2.998e-3584.72NK1 homeobox 1 [Source:NCBI gene;Acc:101166641][more]
nkx1.2lb6.140e-3584.72NK1 homeobox 1 [Source:NCBI gene;Acc:101166641][more]
barhl21.685e-2052.69BarH like homeobox 2 [Source:NCBI gene;Acc:1011744... [more]
ENSORLT00000038356.13.641e-2053.13barH-like 1 homeobox protein [Source:NCBI gene;Acc... [more]
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BLAST of NK homeobox1-1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000051002.10.000e+0100.00SMESG000051002.1[more]
SMESG000041571.11.522e-3285.07SMESG000041571.1[more]
SMESG000077917.12.649e-2990.91SMESG000077917.1[more]
SMESG000021901.14.969e-1843.75SMESG000021901.1[more]
SMESG000022963.12.122e-1757.14SMESG000022963.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30019740 ID=SMED30019740|Name=NK homeobox1-1|organism=Schmidtea mediterranea sexual|type=transcript|length=1267bp
CTCGTTTAATTAATTTTTTTCATTGAAATTAATTGCCAATTTCTGGTTCA
ATCAAAATTTATGAATAATCGTTCATCTGTTTTATCTTGCAATTTCGTAT
TTGATAATATGAGGAACTTCAATTCCGAAACTTTGAAAGAATGGGTAATT
TCGAAAAATACAAATTCCAAGTCAAACGATAAGCCTGACAGAAGCGAACA
GAGATTTTCGAATAACAAACCGATTCATATTAACAATTCCTTTTCAATTC
AAGCTCTACTCGATATTCCAGAAAACTCTCACAAACTCCAAGAAATACCA
CAAAAGATCATTAGTTCTTACACAAACGGGTTTCGAATCAATGCCCAATA
TGTGCCTTATTTGTGTTCCTTGTTGAGCGATGAAAATTTAAACCGATCAA
AAGTCTGTGAGGCTGTAAATGGCATTGGTGCCAAAATTAACCAACTCGAC
AACGGGACAAATGAATCATCAGAAAATCTTCAGTTGAAACCTGATGAATT
GAATGCTATTAATGACGATTTGAGTTCAACGGACAAGAACAATTCGAGCA
ATGAAGCTGACGATACTGAAATCAGCGAAGACAGCTCCATGAAACCGAGA
CGGGCCAGAACATCTTTCACTTATGATCAACTGGTAGCTTTGGAAAATAA
ATTTAAGATTACCCGATATCTGTCGGTTTGCGAAAGATTGAATTTGGCTT
TCAGTTTAAACTTAACCGAAACTCAAGTAAAGATATGGTTTCAAAATCGC
CGGACAAAATGGAAAAAACAAAATCCAGGTTTAGATGTAAACAGCACAAC
AATCACCCCTCCAAGTACCAATCCACGATATTATGATCATTCTTTAATGT
CGAATTTCGCCAATTTTCTCAATAATCGGTCATATCAAGCAATTGACAGC
TCACTGCACAACAATTTGATTGGGCCTTTTCCGCATTCACTTCCAGCAAC
AACCAATGGCAATAATCTACCGAATCACTACTTTTTCAACCATCAATTTC
CAACAAATCCACCTGAAAACTCACGATACCCCCAGTTTTTAAAATCAAGG
GACAGCCTCAAACTCATAGATCACATTCGACATTCAATCAAATCATCCGC
TATCAGTCAGAATATTCCCAATTCTATTCATTCACTAAATTGACAATAAA
CTCAATTGATGCCAATATATCTTCCTTTTTTAGTGCCATCTCCGTTAAAG
AAATACCAACGGAAATATTGTTAATATACCTTATTTTGATTTATCTTCTA
AATGCATTTTTTCCTTT
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protein sequence of SMED30019740-orf-1

>SMED30019740-orf-1 ID=SMED30019740-orf-1|Name=SMED30019740-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=361bp
MNNRSSVLSCNFVFDNMRNFNSETLKEWVISKNTNSKSNDKPDRSEQRFS
NNKPIHINNSFSIQALLDIPENSHKLQEIPQKIISSYTNGFRINAQYVPY
LCSLLSDENLNRSKVCEAVNGIGAKINQLDNGTNESSENLQLKPDELNAI
NDDLSSTDKNNSSNEADDTEISEDSSMKPRRARTSFTYDQLVALENKFKI
TRYLSVCERLNLAFSLNLTETQVKIWFQNRRTKWKKQNPGLDVNSTTITP
PSTNPRYYDHSLMSNFANFLNNRSYQAIDSSLHNNLIGPFPHSLPATTNG
NNLPNHYFFNHQFPTNPPENSRYPQFLKSRDSLKLIDHIRHSIKSSAISQ
NIPNSIHSLN*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000045circular muscle cell
PLANA:0000240body wall musculature
Vocabulary: molecular function
TermDefinition
GO:0043565sequence-specific DNA binding
GO:0003677DNA binding
Vocabulary: biological process
TermDefinition
GO:0006355regulation of transcription, DNA-templated
Vocabulary: INTERPRO
TermDefinition
IPR020479Homeobox_metazoa
IPR001356Homeobox_dom
IPR009057Homeobox-like_sf
IPR017970Homeobox_CS
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR020479Homeobox domain, metazoaPRINTSPR00024HOMEOBOXcoord: 216..226
score: 70.25
coord: 201..212
score: 37.37
coord: 226..235
score: 79.45
IPR001356Homeobox domainSMARTSM00389HOX_1coord: 179..241
e-value: 2.0E-24
score: 97.2
IPR001356Homeobox domainPFAMPF00046Homeodomaincoord: 180..236
e-value: 6.1E-21
score: 74.0
IPR001356Homeobox domainPROSITEPS50071HOMEOBOX_2coord: 177..237
score: 20.358
IPR001356Homeobox domainCDDcd00086homeodomaincoord: 180..238
e-value: 1.69151E-20
score: 81.906
NoneNo IPR availableGENE3DG3DSA:1.10.10.60coord: 148..240
e-value: 2.0E-25
score: 90.8
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 154..179
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 33..53
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 163..179
NoneNo IPR availablePANTHERPTHR24340:SF37NK1 HOMEOBOX 1coord: 75..266
NoneNo IPR availablePANTHERPTHR24340FAMILY NOT NAMEDcoord: 75..266
IPR017970Homeobox, conserved sitePROSITEPS00027HOMEOBOX_1coord: 212..235
IPR009057Homeobox-like domain superfamilySUPERFAMILYSSF46689Homeodomain-likecoord: 167..238