Innexin

Overview
NameInnexin
Smed IDSMED30019735
Length (bp)2135
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Innexin (SMED30019735) t-SNE clustered cells

Violin plots show distribution of expression levels for Innexin (SMED30019735) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Innexin (SMED30019735) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Innexin (SMED30019735) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30019735

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 3

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
posterior sideSMED30019735SMESG000070656.1 dd_Smed_v4_8019_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30019735SMESG000070656.1 dd_Smed_v4_8019_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
posterior muscle cellSMED30019735SMESG000070656.1 dd_Smed_v4_8019_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Innexin vs. Ensembl Celegans
Match: inx-1 (Innexin [Source:UniProtKB/TrEMBL;Acc:Q17394])

HSP 1 Score: 222.631 bits (566), Expect = 2.737e-65
Identity = 138/422 (32.70%), Postives = 214/422 (50.71%), Query Frame = 3 
Query:  129 EDFADKFNFLFTVIVLLICTSIVTMKQYILKPISCYISTISGTNLLEYVENYCWVEGTIPISYDGKIPSTNEEWAELNKYKILYYQWVPFLLSLQAIMFYIPRLIWQIFCYNTTGTDIHHLIVSANQAVHSSDEARTKMVNYIAKTIEQMLYQHRDNRNGRLARFRRSLYKICCFCIMSKRQGTRLLCMYFIIKFLYLTNCILQLYFMKSFLGLNEAGIFFGFKIMKNIINGQDWKSTLVFPRVGYCYVNVKNVGTTNALVAQCVLPVNMLNEKIFFFLWCWXXXXXXXXXXXXXXXXXXXXVYQRRRGFIYRFLKLNQQLKNCDEEKCMVVKFEHQFLRYDGVFLLKMISLNAGDIVAADIVCQLWKIFKSQYANR-------NFLSDGSDDDENHGRTLIRLDNNNHSKPSFDKSNSLQS 1373
            +DF DK N+ +T  ++     IV+ KQY+  PI C++         +Y ENYCWVE T  +      P    E+ +    +I YYQWVPF+L+L+A+ FYIP ++W+   +  +G ++  L   A  A     +AR   V  IA  +E  L              +R +  +   C+  KR    +  +Y  IK LYL N +LQ++ + SFLG +   +F+GF I+++++NG++W+ +  FPRV  C   V+ +G  +    QCVL +NM NEKIF FLW W F  A +  +S+  WI  + +  +   FI ++L+      +   ++  V KF H+FL YDGVF ++MIS +AGDI+A +++  LW  F  +                 S  D N    L+        KP FD SN  + 
Sbjct:   19 DDFVDKLNYHYTSAIIFAFAIIVSAKQYVGYPIQCWVPAQFTDAWEQYTENYCWVENTYYLPLTSAFPL---EYGDRRARQISYYQWVPFVLALEALCFYIPCIMWRGLLHWHSGINVQSLTQMACDARMMDADARAATVQTIAGHMEDAL------------EIQREVTDVSGMCV-QKRWANYVTLLYVFIKMLYLGNVVLQVFMLNSFLGTDN--LFYGFHILRDLLNGREWEVSGNFPRVTMCDFEVRVLGNVHHHTVQCVLMINMFNEKIFLFLWFWYFMVAFVSAVSMFHWIIISFLPGQHMKFIRKYLRAT----DLATDRQSVKKFVHKFLGYDGVFCMRMISAHAGDILATELIVALWHNFNDRVRKSPIEMFEGGVTQSPSKLDANFKTWLL---GQTRGKPPFDGSNPTRG 415
[Close]
BLAST of Innexin vs. Ensembl Celegans
Match: inx-1 (Innexin [Source:UniProtKB/TrEMBL;Acc:Q17394])

HSP 1 Score: 219.55 bits (558), Expect = 1.194e-64
Identity = 131/384 (34.11%), Postives = 205/384 (53.39%), Query Frame = 3 
Query:  129 EDFADKFNFLFTVIVLLICTSIVTMKQYILKPISCYISTISGTNLLEYVENYCWVEGTIPISYDGKIPSTNEEWAELNKYKILYYQWVPFLLSLQAIMFYIPRLIWQIFCYNTTGTDIHHLIVSANQAVHSSDEARTKMVNYIAKTIEQMLYQHRDNRNGRLARFRRSLYKICCFCIMSKRQGTRLLCMYFIIKFLYLTNCILQLYFMKSFLGLNEAGIFFGFKIMKNIINGQDWKSTLVFPRVGYCYVNVKNVGTTNALVAQCVLPVNMLNEKIFFFLWCWXXXXXXXXXXXXXXXXXXXXVYQRRRGFIYRFLKLNQQLKNCDEEKCMVVKFEHQFLRYDGVFLLKMISLNAGDIVAADIVCQLWKIFKSQYANRNFLSDGS 1280
            +DF DK N+ +T  ++     IV+ KQY+  PI C++         +Y ENYCWVE T  +      P    E+ +    +I YYQWVPF+L+L+A+ FYIP ++W+   +  +G ++  L   A  A     +AR   V  IA  +E  L              +R +  +   C+  KR    +  +Y  IK LYL N +LQ++ + SFLG +   +F+GF I+++++NG++W+ +  FPRV  C   V+ +G  +    QCVL +NM NEKIF FLW W F  A +  +S+  WI  + +  +   FI ++L+      +   ++  V KF H+FL YDGVF ++MIS +AGDI+A +++  LW  F  +     F S  S
Sbjct:   19 DDFVDKLNYHYTSAIIFAFAIIVSAKQYVGYPIQCWVPAQFTDAWEQYTENYCWVENTYYLPLTSAFPL---EYGDRRARQISYYQWVPFVLALEALCFYIPCIMWRGLLHWHSGINVQSLTQMACDARMMDADARAATVQTIAGHMEDAL------------EIQREVTDVSGMCV-QKRWANYVTLLYVFIKMLYLGNVVLQVFMLNSFLGTDN--LFYGFHILRDLLNGREWEVSGNFPRVTMCDFEVRVLGNVHHHTVQCVLMINMFNEKIFLFLWFWYFMVAFVSAVSMFHWIIISFLPGQHMKFIRKYLRAT----DLATDRQSVKKFVHKFLGYDGVFCMRMISAHAGDILATELIVALWHNFNDRVRKIQFNSTES 380
[Close]
BLAST of Innexin vs. Ensembl Celegans
Match: inx-1 (Innexin [Source:UniProtKB/TrEMBL;Acc:Q17394])

HSP 1 Score: 219.55 bits (558), Expect = 1.194e-64
Identity = 131/384 (34.11%), Postives = 205/384 (53.39%), Query Frame = 3 
Query:  129 EDFADKFNFLFTVIVLLICTSIVTMKQYILKPISCYISTISGTNLLEYVENYCWVEGTIPISYDGKIPSTNEEWAELNKYKILYYQWVPFLLSLQAIMFYIPRLIWQIFCYNTTGTDIHHLIVSANQAVHSSDEARTKMVNYIAKTIEQMLYQHRDNRNGRLARFRRSLYKICCFCIMSKRQGTRLLCMYFIIKFLYLTNCILQLYFMKSFLGLNEAGIFFGFKIMKNIINGQDWKSTLVFPRVGYCYVNVKNVGTTNALVAQCVLPVNMLNEKIFFFLWCWXXXXXXXXXXXXXXXXXXXXVYQRRRGFIYRFLKLNQQLKNCDEEKCMVVKFEHQFLRYDGVFLLKMISLNAGDIVAADIVCQLWKIFKSQYANRNFLSDGS 1280
            +DF DK N+ +T  ++     IV+ KQY+  PI C++         +Y ENYCWVE T  +      P    E+ +    +I YYQWVPF+L+L+A+ FYIP ++W+   +  +G ++  L   A  A     +AR   V  IA  +E  L              +R +  +   C+  KR    +  +Y  IK LYL N +LQ++ + SFLG +   +F+GF I+++++NG++W+ +  FPRV  C   V+ +G  +    QCVL +NM NEKIF FLW W F  A +  +S+  WI  + +  +   FI ++L+      +   ++  V KF H+FL YDGVF ++MIS +AGDI+A +++  LW  F  +     F S  S
Sbjct:   19 DDFVDKLNYHYTSAIIFAFAIIVSAKQYVGYPIQCWVPAQFTDAWEQYTENYCWVENTYYLPLTSAFPL---EYGDRRARQISYYQWVPFVLALEALCFYIPCIMWRGLLHWHSGINVQSLTQMACDARMMDADARAATVQTIAGHMEDAL------------EIQREVTDVSGMCV-QKRWANYVTLLYVFIKMLYLGNVVLQVFMLNSFLGTDN--LFYGFHILRDLLNGREWEVSGNFPRVTMCDFEVRVLGNVHHHTVQCVLMINMFNEKIFLFLWFWYFMVAFVSAVSMFHWIIISFLPGQHMKFIRKYLRAT----DLATDRQSVKKFVHKFLGYDGVFCMRMISAHAGDILATELIVALWHNFNDRVRKIQFNSTES 380
[Close]
BLAST of Innexin vs. Ensembl Celegans
Match: unc-9 (Innexin unc-9 [Source:UniProtKB/Swiss-Prot;Acc:O01393])

HSP 1 Score: 201.83 bits (512), Expect = 5.780e-58
Identity = 116/368 (31.52%), Postives = 201/368 (54.62%), Query Frame = 3 
Query:  129 EDFADKFNFLFTVIVLLICTSIVTMKQYILKPISCYISTISGTNLLEYVENYCWVEGTIPISYDGKIPSTNEEWAELNKYKILYYQWVPFLLSLQAIMFYIPRLIWQIFCYNTTGTDIHHLIVSANQAVHSSDEARTKMVNYIAKTIEQMLY-QHRDNRNGRLARFRRSLYKICCFCIMSKRQGTRLLCMYFIIKFLYLTNCILQLYFMKSFLGLNEAGIFFGFKIMKNIINGQDWKSTLVFPRVGYCYVNVKNVGTTNALVAQCVLPVNMLNEKIFFFLWCWXXXXXXXXXXXXXXXXXXXXVYQRRRGFIYRFLKLNQQLKNCDEEKCMVVKFEHQFLRYDGVFLLKMISLNAGDIVAADIVCQLW 1229
            +D  DK N+ +T  ++ +   +V+ KQY+  PI C++       + +Y ENYCWV+ T  +     IP     +AE    +I YYQWVPF+L+L+A++FY+P ++W++  + + G  +  L+  A  +     E+R + +  IA  +E+ L+ +H+     RL        K+    I ++  G  +  +Y  +K LY  N + Q++ + +FLG      ++G +++ +++NG++W+ +  FPRV  C   VK +G  +    QCVL +NM NEKIF FLW W F  A     S+  WI+ + V  R+  F+ ++L   +  K  D +   + +F   FLR DGVFLL+M++ +AG++   ++   LW
Sbjct:   21 DDIIDKLNYYYTTAIITVFAILVSAKQYVGFPIQCWVPATFTEPMEQYTENYCWVQNTYFLPLHDYIP---HNYAERENRQIGYYQWVPFVLALEALLFYVPTIVWRLLSWQS-GIHVQSLVQMACDSRLLDLESRNRALQTIATNVEEALHVKHQVMSGNRL--------KLLNLIICTRSSGAAVTFLYISVKILYTVNIVGQIFLLNTFLG--NRSKWYGLQVLNDLMNGREWEESGHFPRVTLCDFEVKVLGNVHRHTVQCVLMINMFNEKIFLFLWFWYFLLAGATLCSLFYWIYISVVPSRQLNFVGKYLTGIEGYKMVDSQS--LRRFVFHFLRQDGVFLLRMVATHAGELPCYELAKTLW 372
[Close]
BLAST of Innexin vs. Ensembl Celegans
Match: unc-7 (Innexin unc-7 [Source:UniProtKB/Swiss-Prot;Acc:Q03412])

HSP 1 Score: 200.675 bits (509), Expect = 1.948e-57
Identity = 117/373 (31.37%), Postives = 206/373 (55.23%), Query Frame = 3 
Query:  129 EDFADKFNFLFTVIVLLICTSIVTMKQYILKPISCYISTISGTNLLEYVENYCWVEGTIPISYDGKIPSTNEEWAELNKYKILYYQWVPFLLSLQAIMFYIPRLIWQIFCYNTTGTDIHHLIVSANQAVHSSDEARTKMVNYIAKTIEQMLYQHRDNRNGRLARFRRSLYKICCFCIMSKRQGTRLLCMYFIIKFLYLTNCILQLYFMKSFLGLNEAGIFFGFKIMKNIINGQDWKSTLVFPRVGYCYVNVKNVGTTNALVAQCVLPVNMLNEKIFFFLWCWXXXXXXXXXXXXXXXXXXXXVYQRRRGFIYRFLK-LNQQLKNCDEEKCMVVKFEHQFLRYDGVFLLKMISLNAGDIVAADIVCQLWKIFKS 1244
            +DF DK N+ +T  +L     +V+ KQY+  PI C++       + +Y ENYCWV+ T  +     IP   E ++  N+ +I YYQWVPF+L+++A++FY+P ++W+   Y  +G ++  L+  A  A     E +T+ V  +A+ ++  +     +R G  +R   S  ++   C   +  G  +  +Y  IK LY  N +LQ + +   LG N+    +GF ++K++++  +W+ T +FPRV  C   V+ +G  +    QCVL +NM NEKIF FLW W  +  I+   + + WI    +  +   F+ ++L+ L         +   + KF + FLR DGVF+L+MIS +AG++++++++  LW+ F +
Sbjct:   19 DDFVDKLNYYYTTTILASFALLVSAKQYVGFPIQCWVPATFTDAMEQYTENYCWVQNTYWVPMQEDIP--REIYSRRNR-QIGYYQWVPFILAIEALLFYVPCILWRGLLYWHSGINLQGLVQMACDARLMDSEIKTRTVYTMARHMQDEVQLTNIDRQGH-SRSCFSNLQLGANC--GRHCGCYVTMLYIGIKVLYSANVLLQFFLLNHLLGSNDLA--YGFSLLKDLMHAIEWEQTGMFPRVTLCDFEVRVLGNIHRHTVQCVLMINMFNEKIFLFLWFWFLTCGIVTVCNTMYWILIMFIPSQGMSFVRKYLRVLPDHPAKPIADDVTLRKFTNNFLRKDGVFMLRMISTHAGELMSSELILALWQDFNN 383
[Close]
BLAST of Innexin vs. Ensembl Fly
Match: shakB (gene:FBgn0085387 transcript:FBtr0112571)

HSP 1 Score: 93.9745 bits (232), Expect = 2.733e-20
Identity = 81/294 (27.55%), Postives = 133/294 (45.24%), Query Frame = 3 
Query:  144 KFNFLFTVIVLLICTSIVTMKQYILKPISCYISTISGTNLLEYVEN-YCWVEGT------------IPISYDGKIPSTNEEWAELNKYKILYYQWVPFLLSLQAIMFYIPRLIWQIFCYNTTGTDIHHLIVSANQAVHSSDEARTKMVNYIAKTIEQMLYQHRDNRNGRLARFRRSLYKICCFCIMSKRQGTRLLCMYFIIKFLYLTNCILQLYFMKSFLGLNEAGIFFGFKIMKNIINGQDWK---STLVFPRVGYC-YVNVKNVGTTNALVAQCVLPVNMLNEKIFFFLWCW 974
            + ++  TV++L+  + I+T +QY+  PI C    +   ++ E V N YCW++ T            + + Y G I +++ + A+   YK  YYQWV F L  QAI+FY PR +W+    +  G  IH LI+  +  + S  E + K    +    E + Y      N    R                         Y++ + L L N I Q++ M  F   +   I FG K++  +   Q+ +      +FPR+  C +    + G      A C+LP+N++NEKI+ FLW W
Sbjct:   25 RLHYSITVMILMSFSLIITTRQYVGNPIDC----VHTKDIPEDVLNTYCWIQSTYTLKSLFLKKQGVSVPYPG-IGNSDGDPADKKHYK--YYQWVCFCLFFQAILFYTPRWLWK----SWEGGKIHALIMDLDIGICSEAEKKQKKKLLLDYLWENLRYH-----NWWAYR-------------------------YYVCELLALINVIGQMFLMNRF--FDGEFITFGLKVIDYMETDQEDRMDPMIYIFPRMTKCTFFKYGSSGEVEKHDAICILPLNVVNEKIYIFLWFW 275
[Close]
BLAST of Innexin vs. Ensembl Fly
Match: ogre (gene:FBgn0004646 transcript:FBtr0071037)

HSP 1 Score: 91.2781 bits (225), Expect = 2.148e-19
Identity = 74/288 (25.69%), Postives = 129/288 (44.79%), Query Frame = 3 
Query:  159 FTVIVLLICTSIVTMKQYILKPISCYISTISGTNLLEYVENYCWVEG--TIPISYDGKI------PSTNEEWAELNKYK-ILYYQWVPFLLSLQAIMFYIPRLIWQIFCYNTTGTDIHHLIVSANQAVHSSDEARTK---MVNYIAKTIEQMLYQHRDNRNGRLARFRRSLYKICCFCIMSKRQGTRLLCMYFIIKFLYLTNCILQLYFMKSFLGLNEAGIFFGFKIMKNIINGQDWK---STLVFPRVGYC-YVNVKNVGTTNALVAQCVLPVNMLNEKIFFFLWCW 974
            FT ++LL C+ I+T  QY+ +PISC ++ +        V  +CW+    T+P ++  ++      P    ++ + +  K   YYQWV F+L  QA+  Y P+ +W  F     G  +  +++  N  + + +E   K   +++Y+ K ++                 R  LY I                 Y+  +FL   N I+Q+Y M  F   +   + +G  IMK     Q+ +      VFPRV  C +      G+     + C+LP+N++NEK + F+W W
Sbjct:   30 FTTVLLLTCSLIITATQYVGQPISCIVNGVPP----HVVNTFCWIHSTFTMPDAFRRQVGREVAHPGVANDFGDEDAKKYYTYYQWVCFVLFFQAMACYTPKFLWNKF----EGGLMRMIVMGLNITICTREEKEAKRDALLDYLIKHVK-----------------RHKLYAI----------------RYWACEFLCCINIIVQMYLMNRF--FDGEFLSYGTNIMKLSDVPQEQRVDPMVYVFPRVTKCTFHKYGPSGSLQKHDSLCILPLNIVNEKTYVFIWFW 274
[Close]
BLAST of Innexin vs. Ensembl Fly
Match: ogre (gene:FBgn0004646 transcript:FBtr0334881)

HSP 1 Score: 91.2781 bits (225), Expect = 2.148e-19
Identity = 74/288 (25.69%), Postives = 129/288 (44.79%), Query Frame = 3 
Query:  159 FTVIVLLICTSIVTMKQYILKPISCYISTISGTNLLEYVENYCWVEG--TIPISYDGKI------PSTNEEWAELNKYK-ILYYQWVPFLLSLQAIMFYIPRLIWQIFCYNTTGTDIHHLIVSANQAVHSSDEARTK---MVNYIAKTIEQMLYQHRDNRNGRLARFRRSLYKICCFCIMSKRQGTRLLCMYFIIKFLYLTNCILQLYFMKSFLGLNEAGIFFGFKIMKNIINGQDWK---STLVFPRVGYC-YVNVKNVGTTNALVAQCVLPVNMLNEKIFFFLWCW 974
            FT ++LL C+ I+T  QY+ +PISC ++ +        V  +CW+    T+P ++  ++      P    ++ + +  K   YYQWV F+L  QA+  Y P+ +W  F     G  +  +++  N  + + +E   K   +++Y+ K ++                 R  LY I                 Y+  +FL   N I+Q+Y M  F   +   + +G  IMK     Q+ +      VFPRV  C +      G+     + C+LP+N++NEK + F+W W
Sbjct:   30 FTTVLLLTCSLIITATQYVGQPISCIVNGVPP----HVVNTFCWIHSTFTMPDAFRRQVGREVAHPGVANDFGDEDAKKYYTYYQWVCFVLFFQAMACYTPKFLWNKF----EGGLMRMIVMGLNITICTREEKEAKRDALLDYLIKHVK-----------------RHKLYAI----------------RYWACEFLCCINIIVQMYLMNRF--FDGEFLSYGTNIMKLSDVPQEQRVDPMVYVFPRVTKCTFHKYGPSGSLQKHDSLCILPLNIVNEKTYVFIWFW 274
[Close]
BLAST of Innexin vs. Ensembl Fly
Match: ogre (gene:FBgn0004646 transcript:FBtr0309875)

HSP 1 Score: 91.2781 bits (225), Expect = 2.148e-19
Identity = 74/288 (25.69%), Postives = 129/288 (44.79%), Query Frame = 3 
Query:  159 FTVIVLLICTSIVTMKQYILKPISCYISTISGTNLLEYVENYCWVEG--TIPISYDGKI------PSTNEEWAELNKYK-ILYYQWVPFLLSLQAIMFYIPRLIWQIFCYNTTGTDIHHLIVSANQAVHSSDEARTK---MVNYIAKTIEQMLYQHRDNRNGRLARFRRSLYKICCFCIMSKRQGTRLLCMYFIIKFLYLTNCILQLYFMKSFLGLNEAGIFFGFKIMKNIINGQDWK---STLVFPRVGYC-YVNVKNVGTTNALVAQCVLPVNMLNEKIFFFLWCW 974
            FT ++LL C+ I+T  QY+ +PISC ++ +        V  +CW+    T+P ++  ++      P    ++ + +  K   YYQWV F+L  QA+  Y P+ +W  F     G  +  +++  N  + + +E   K   +++Y+ K ++                 R  LY I                 Y+  +FL   N I+Q+Y M  F   +   + +G  IMK     Q+ +      VFPRV  C +      G+     + C+LP+N++NEK + F+W W
Sbjct:   30 FTTVLLLTCSLIITATQYVGQPISCIVNGVPP----HVVNTFCWIHSTFTMPDAFRRQVGREVAHPGVANDFGDEDAKKYYTYYQWVCFVLFFQAMACYTPKFLWNKF----EGGLMRMIVMGLNITICTREEKEAKRDALLDYLIKHVK-----------------RHKLYAI----------------RYWACEFLCCINIIVQMYLMNRF--FDGEFLSYGTNIMKLSDVPQEQRVDPMVYVFPRVTKCTFHKYGPSGSLQKHDSLCILPLNIVNEKTYVFIWFW 274
[Close]
BLAST of Innexin vs. Ensembl Fly
Match: ogre (gene:FBgn0004646 transcript:FBtr0071036)

HSP 1 Score: 91.2781 bits (225), Expect = 2.148e-19
Identity = 74/288 (25.69%), Postives = 129/288 (44.79%), Query Frame = 3 
Query:  159 FTVIVLLICTSIVTMKQYILKPISCYISTISGTNLLEYVENYCWVEG--TIPISYDGKI------PSTNEEWAELNKYK-ILYYQWVPFLLSLQAIMFYIPRLIWQIFCYNTTGTDIHHLIVSANQAVHSSDEARTK---MVNYIAKTIEQMLYQHRDNRNGRLARFRRSLYKICCFCIMSKRQGTRLLCMYFIIKFLYLTNCILQLYFMKSFLGLNEAGIFFGFKIMKNIINGQDWK---STLVFPRVGYC-YVNVKNVGTTNALVAQCVLPVNMLNEKIFFFLWCW 974
            FT ++LL C+ I+T  QY+ +PISC ++ +        V  +CW+    T+P ++  ++      P    ++ + +  K   YYQWV F+L  QA+  Y P+ +W  F     G  +  +++  N  + + +E   K   +++Y+ K ++                 R  LY I                 Y+  +FL   N I+Q+Y M  F   +   + +G  IMK     Q+ +      VFPRV  C +      G+     + C+LP+N++NEK + F+W W
Sbjct:   30 FTTVLLLTCSLIITATQYVGQPISCIVNGVPP----HVVNTFCWIHSTFTMPDAFRRQVGREVAHPGVANDFGDEDAKKYYTYYQWVCFVLFFQAMACYTPKFLWNKF----EGGLMRMIVMGLNITICTREEKEAKRDALLDYLIKHVK-----------------RHKLYAI----------------RYWACEFLCCINIIVQMYLMNRF--FDGEFLSYGTNIMKLSDVPQEQRVDPMVYVFPRVTKCTFHKYGPSGSLQKHDSLCILPLNIVNEKTYVFIWFW 274
[Close]
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|O01393|UNC9_CAEEL (Innexin unc-9 OS=Caenorhabditis elegans OX=6239 GN=unc-9 PE=1 SV=1)

HSP 1 Score: 201.83 bits (512), Expect = 7.353e-57
Identity = 116/368 (31.52%), Postives = 201/368 (54.62%), Query Frame = 3 
Query:  129 EDFADKFNFLFTVIVLLICTSIVTMKQYILKPISCYISTISGTNLLEYVENYCWVEGTIPISYDGKIPSTNEEWAELNKYKILYYQWVPFLLSLQAIMFYIPRLIWQIFCYNTTGTDIHHLIVSANQAVHSSDEARTKMVNYIAKTIEQMLY-QHRDNRNGRLARFRRSLYKICCFCIMSKRQGTRLLCMYFIIKFLYLTNCILQLYFMKSFLGLNEAGIFFGFKIMKNIINGQDWKSTLVFPRVGYCYVNVKNVGTTNALVAQCVLPVNMLNEKIFFFLWCWXXXXXXXXXXXXXXXXXXXXVYQRRRGFIYRFLKLNQQLKNCDEEKCMVVKFEHQFLRYDGVFLLKMISLNAGDIVAADIVCQLW 1229
            +D  DK N+ +T  ++ +   +V+ KQY+  PI C++       + +Y ENYCWV+ T  +     IP     +AE    +I YYQWVPF+L+L+A++FY+P ++W++  + + G  +  L+  A  +     E+R + +  IA  +E+ L+ +H+     RL        K+    I ++  G  +  +Y  +K LY  N + Q++ + +FLG      ++G +++ +++NG++W+ +  FPRV  C   VK +G  +    QCVL +NM NEKIF FLW W F  A     S+  WI+ + V  R+  F+ ++L   +  K  D +   + +F   FLR DGVFLL+M++ +AG++   ++   LW
Sbjct:   21 DDIIDKLNYYYTTAIITVFAILVSAKQYVGFPIQCWVPATFTEPMEQYTENYCWVQNTYFLPLHDYIP---HNYAERENRQIGYYQWVPFVLALEALLFYVPTIVWRLLSWQS-GIHVQSLVQMACDSRLLDLESRNRALQTIATNVEEALHVKHQVMSGNRL--------KLLNLIICTRSSGAAVTFLYISVKILYTVNIVGQIFLLNTFLG--NRSKWYGLQVLNDLMNGREWEESGHFPRVTLCDFEVKVLGNVHRHTVQCVLMINMFNEKIFLFLWFWYFLLAGATLCSLFYWIYISVVPSRQLNFVGKYLTGIEGYKMVDSQS--LRRFVFHFLRQDGVFLLRMVATHAGELPCYELAKTLW 372
[Close]
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|Q03412|UNC7_CAEEL (Innexin unc-7 OS=Caenorhabditis elegans OX=6239 GN=unc-7 PE=1 SV=1)

HSP 1 Score: 202.601 bits (514), Expect = 8.757e-56
Identity = 117/371 (31.54%), Postives = 206/371 (55.53%), Query Frame = 3 
Query:  129 EDFADKFNFLFTVIVLLICTSIVTMKQYILKPISCYISTISGTNLLEYVENYCWVEGTIPISYDGKIPSTNEEWAELNKYKILYYQWVPFLLSLQAIMFYIPRLIWQIFCYNTTGTDIHHLIVSANQAVHSSDEARTKMVNYIAKTIEQMLYQHRDNRNGRLARFRRSLYKICCFCIMSKRQGTRLLCMYFIIKFLYLTNCILQLYFMKSFLGLNEAGIFFGFKIMKNIINGQDWKSTLVFPRVGYCYVNVKNVGTTNALVAQCVLPVNMLNEKIFFFLWCWXXXXXXXXXXXXXXXXXXXXVYQRRRGFIYRFLK-LNQQLKNCDEEKCMVVKFEHQFLRYDGVFLLKMISLNAGDIVAADIVCQLWKIF 1238
            +DF DK N+ +T  +L     +V+ KQY+  PI C++       + +Y ENYCWV+ T  +     IP   E ++  N+ +I YYQWVPF+L+++A++FY+P ++W+   Y  +G ++  L+  A  A     E +T+ V  +A+ ++  +     +R G  +R   S  ++   C   +  G  +  +Y  IK LY  N +LQ + +   LG N+  + +GF ++K++++  +W+ T +FPRV  C   V+ +G  +    QCVL +NM NEKIF FLW W  +  I+   + + WI    +  +   F+ ++L+ L         +   + KF + FLR DGVF+L+MIS +AG++++++++  LW+ F
Sbjct:  139 DDFVDKLNYYYTTTILASFALLVSAKQYVGFPIQCWVPATFTDAMEQYTENYCWVQNTYWVPMQEDIP--REIYSRRNR-QIGYYQWVPFILAIEALLFYVPCILWRGLLYWHSGINLQGLVQMACDARLMDSEIKTRTVYTMARHMQDEVQLTNIDRQGH-SRSCFSNLQLGANC--GRHCGCYVTMLYIGIKVLYSANVLLQFFLLNHLLGSND--LAYGFSLLKDLMHAIEWEQTGMFPRVTLCDFEVRVLGNIHRHTVQCVLMINMFNEKIFLFLWFWFLTCGIVTVCNTMYWILIMFIPSQGMSFVRKYLRVLPDHPAKPIADDVTLRKFTNNFLRKDGVFMLRMISTHAGELMSSELILALWQDF 501
[Close]
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|Q23157|INX11_CAEEL (Innexin-11 OS=Caenorhabditis elegans OX=6239 GN=inx-11 PE=3 SV=1)

HSP 1 Score: 183.726 bits (465), Expect = 1.940e-49
Identity = 117/391 (29.92%), Postives = 187/391 (47.83%), Query Frame = 3 
Query:  129 EDFADKFNFLFTVIVLLICTSIVTMKQYILKPISCYISTISGTNLLEYVENYCWVEGTIPISYDGKIPSTNEEWAELNKYKILYYQWVPFLLSLQAIMFYIPRLIWQIFCYNTTGTDIHHLIVSANQAVHSSDEARTKMVNYIAKTIEQMLYQHRDNRNGRLARFRRSLYKICCFCIMSKRQGTRLLCMYFIIKFLYLTNCILQLYFMKSFLGLNEAGIFFGFKIMKNIINGQDWKSTLVFPRVGYCYVNVKNVGTTNALVAQCVLPVNMLNEKIFFFLWCWXXXXXXXXXXXXXXXXXXXXVYQRRRGFIYRFLKL----NQQLKNCDEEKCMVVKFEHQFLRYDGVFLLKMISLNAGDIVAADIVCQLWKIFKSQYANRNFLSDGSDDD 1289
            +D++D+ N+L T  +LL  + +++ KQ+  +PI C        +  +Y ENYCW + T  +     +    +E       ++ YYQWVPF L LQA  F  P  +W+ F  N +G  IH ++  A  + +  +E R K +  + + +   L          + R +  ++K   F       G  +  +Y   K LY  N   QLY M  FLG N    ++GF ++++I+ G+ W+ +  FPR   C   V+ V        QCVL +N+ NEKIF  LW W     +  T+S++ W          + F+ + L L    N   +N   E   V KF  Q+L  DGVF+L+M+S +AG I A D+V  L++ +  Q  N++       DD
Sbjct:   20 DDWSDRLNYLMTPNILLAFSVLISFKQFGGRPIECMFPNKFPGSWEQYAENYCWSQDTYFVEPTQDVSLLKKEERYTPDRQLSYYQWVPFFLLLQAAFFRAPSYLWKYFS-NHSGIRIHEVVEKAKDSANVEEEVREKNILILKRHLSSAL-----RFQANMERKKVQVHKTVTFLNFQYSSGF-ISWIYLFTKVLYFLNVFAQLYLMNYFLGTNRHH-WYGFGVVQDIVQGEPWERSGYFPRAAVCDFEVRQVANIQRYSVQCVLVINIFNEKIFVLLWFWYVILLLSSTVSLVQWFIVLVFPCFSKWFVKQHLALSTLQNFNQRNSRREDSDVSKFVTQYLHKDGVFVLRMVSSHAGIIFATDLVQALYEAYDFQDKNKDVQGSPVSDD 402
[Close]
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|Q27295|EAT5_CAEEL (Innexin eat-5 OS=Caenorhabditis elegans OX=6239 GN=eat-5 PE=2 SV=1)

HSP 1 Score: 181.03 bits (458), Expect = 6.797e-49
Identity = 118/425 (27.76%), Postives = 207/425 (48.71%), Query Frame = 3 
Query:  138 ADKFNFLFTVIVLLICTSIVTMKQYILKPISCYISTISGTNLLEYVENYCWVEGTIPISYDGKIPSTNEEWAELNKYKILYYQWVPFLLSLQAIMFYIPRLIWQIFCYNTTGTDIHHLIVSANQAVHSSDEARTKMVNYIAKTIEQMLYQHR-DNRNGRLARFRRSLYKICCFCIMSKRQGTRLLCMYFIIKFLYLTNCILQLYFMKSFLGLNEAGIFFGFKIMKNIINGQDWKSTLVFPRVGYCYVNVKNVGTTNALVAQCVLPVNMLNEKIFFFLWCWXXXXXXXXXXXXXXXXXXXXVYQRRRGFIYRFLKLNQQLKNCD---EEKCMVVKFEHQFL---------RYDGVFLLKMISLNAGDIVAADIVCQLWKIFKSQYANRNFLSDGSDDDENHGRTLIRLDNNNHSKPSFDKSNSLQS 1373
             D+ N+ ++ ++++  +  +T +QY+  P+ C++         +Y E+YC+V  T  +  + K+P T EE       +++YYQW PF+++++A  FY+P + W +     +G +I  L+ +A +A  +  E R K ++ I + I   L + R +    ++A+ +R         I   + G  +  +Y + K +Y+TN  LQ Y    FLG N+   ++G +I+ +I+ G DW+ +  FPR+  C   V+ +G       QCVL +NM NEKIF FL+ W      +     I   +      +   F+ +FL    Q +N +   EE+ +  K +H  L           D + LLKMI+ + GDIV  +IV ++W  F  + A                  L R  +N+H   +  KS+SL+S
Sbjct:   20 TDRLNYYYSTLIIMGMSLTITARQYVGSPLQCWVPAQFTKAWEQYAEDYCFVYNTYWVKPNDKVPLTVEERV---SQQLIYYQWAPFIMAIEAAFFYLPVIFWSMLS-TKSGINIIKLVETAQKAEGAESEERKKQIDIICRHISNNLRKRRNEEETTKMAKIQR---------IFGMQHGKYITNVYLVTKLIYMTNSFLQFYSTNKFLGQNDP--YWGMRILDDILKGTDWEHSGNFPRIAMCDFQVRVLGNLQRYSIQCVLTLNMFNEKIFLFLYIWFLLVFFVTLFDSIFLCYNMFSSHKLVEFLQQFLDNQDQDENDEKKPEERKVYRKEQHSILLSEFCLHKFTPDIIILLKMINNHTGDIVCTEIVGRMWNEFLERDAK---------------LVLQRFVDNDHHMET--KSSSLKS 412
[Close]
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|A8WVX4|INX19_CAEBR (Innexin-19 OS=Caenorhabditis briggsae OX=6238 GN=inx-19 PE=3 SV=3)

HSP 1 Score: 178.718 bits (452), Expect = 5.538e-48
Identity = 124/404 (30.69%), Postives = 206/404 (50.99%), Query Frame = 3 
Query:  123 GVEDFADKFNFLFTVIVLLICTSIVTMKQYILKPISCYISTISGTNLLEYVENYCWVEGTIPISYDGKIPSTNEEWAELNKYKILYYQWVPFLLSLQAIMFYIPRLIWQIFCYNTTGTDIHHLIVSANQAVHSSDEA-RTKMVNYIA-KTIEQMLYQHRDNR---NGRLARFRRSLYKICCFCIMSKRQGTRLLCMYFIIKFLYLTNCILQLYFMKSFLGLNEAGIFFGFKIMKNIINGQDWKSTLVFPRVGYCYVNVKNVGTTNALVAQCVLPVNMLNEKIFFFLWCWXXXXXXXXXXXXXXXXXXXXVYQRRRGFIYRFL---------KLNQQLKNCDEEKCMVV---------KFEHQFLRYDGVFLLKMISLNAGDIVAADIVCQLWKIFKSQYANRNF 1265
            G +D  D+ N+ +T ++L +C  +++ KQY   PI C+++  S  ++ EY+E+YCW++ T  I     +P  +    E    +I YYQWVPF+L  +A+MF +P + W++ C   +G +I  LI +A  A    D + R K V  I    ++ +  Q  + R    G +AR + S +            G  +  +Y   K LY  N + Q + + + L  +E  +FFGF+++ +I  G+ W  T  FPRV  C   V+ +   N    QC L +N++NEK+F FLWCW    AI+ T S I WI  + ++  +  ++ +F+         KL +  K+   E+   V          F   FL+ DG+ +L+MIS +AGD++   +V  LW+    +Y  RN+
Sbjct:   19 GDDDAVDRLNYYYTPLILAVCCLVISAKQYGGTPIECWVNPHSRESMEEYIESYCWIQNTYWIPMYENVPDDHTAREE---KQIGYYQWVPFILIAEALMFSLPCIFWRL-CSFQSGLNIQTLINAACDAQALLDYSDRQKAVEAITCNFVDNLDLQSPNGRIRARGWIARIKFSRF----------LSGQCISIVYSFTKLLYSVNVVAQFFILNACLKSSEF-VFFGFQVLSDIWAGRPWTETGHFPRVTLCDFEVRYLANLNRYTVQCALLINIINEKVFAFLWCWYMILAIITTCSFIYWIANSFIHSEKVDYVMKFIQIAESSEYKKLQKFEKDATVERLYTVIAFAPHLLDSFVSDFLKSDGILMLRMISNHAGDMIVVQLVRNLWQ----EYRERNW 403
[Close]
BLAST of Innexin vs. TrEMBL
Match: G7YJJ0 (Innexin OS=Clonorchis sinensis OX=79923 GN=inx PE=3 SV=1)

HSP 1 Score: 502.671 bits (1293), Expect = 3.374e-169
Identity = 244/457 (53.39%), Postives = 331/457 (72.43%), Query Frame = 3 
Query:   66 MVAGQFIDYLTKFQVSNYAGVEDFADKFNFLFTVIVLLICTSIVTMKQYILKPISCYIST-ISGTNLLEYVENYCWVEGTIPISYDGKIPSTNEEWAELNKYKILYYQWVPFLLSLQAIMFYIPRLIWQIFCYNTTGTDIHHLIVSANQAVHSSDEARTKMVNYIAKTIEQMLYQHRDNRNGRLARFRRSLYKICCFCIMSKRQGTRLLCMYFIIKFLYLTNCILQLYFMKSFLGLN-EAGIFFGFKIMKNIINGQDWKSTLVFPRVGYCYVNVKNVGTTNALVAQCVLPVNMLNEKIFFFLWCWXXXXXXXXXXXXXXXXXXXXVYQRRRGFIYRFLKLNQQLKNCDEEKCMVVKFEHQFLRYDGVFLLKMISLNAGDIVAADIVCQLWKIFKSQYANRNFLSDGSDDDENHGRTLIRLDNNNHSKPSFDKSNSLQSAFPSAPISPFDVENSHKKN 1430
            MV  +F+DY++KFQV+ Y GVEDFADKFNFL TV++LL+CT++VT+KQY++KPISCY++T I G NLL+YVENYCWV+GTIPI+Y GK+P T+  W E+ K+K+LYYQWVPF+L LQ IMFY+PR+IWQ+ CYN TGTDI HL++SANQAVH++D+ RTKM+ ++A+T+EQML+QHR+ RN   +  RR L+K C   ++SKR GTRL  +Y  IK LYL N + Q++ M++FLGL  +   FFG  I ++I++G+DW+ TLVFPRVGYC V V+++G +N +  QCVLPVNMLNE+I+ FLW WI  +A L  ISI  W  R S  + R  FI ++LKL + L   D  + MV KF+ QFLR DG+FLL+MI++NAGD++ +DIVCQLWKIFK++Y  R+      + +E H     R+  +  +    D    +    P+AP    DVEN   K 
Sbjct:    1 MVGSEFLDYISKFQVATYVGVEDFADKFNFLVTVMILLLCTTVVTVKQYMMKPISCYMATDIGGKNLLDYVENYCWVQGTIPIAYAGKMPETDAAWEEMEKHKLLYYQWVPFVLGLQCIMFYVPRVIWQMICYNRTGTDIQHLVLSANQAVHATDDQRTKMIQHVARTLEQMLFQHREYRNDVWSHIRRRLWKTCSLLVVSKRLGTRLFAIYLFIKCLYLVNAVGQVFMMQTFLGLRYDNYSFFGIAIARDILSGKDWQRTLVFPRVGYCLVPVRHMGASNYVTGQCVLPVNMLNERIYVFLWFWIVLAATLTAISIPTWFMRMSYQKSRTCFIKKYLKLGEVLTKKD--RGMVEKFKRQFLRQDGIFLLRMIAINAGDLICSDIVCQLWKIFKTRYFFRDLTMSDEEQEEEH-----RVQLSRGTVEVTDLERCVSDPTPTAPPVDDDVENMKSKR 450
[Close]
BLAST of Innexin vs. TrEMBL
Match: A0A4S2LNY2 (Innexin OS=Opisthorchis felineus OX=147828 GN=inx PE=3 SV=1)

HSP 1 Score: 498.049 bits (1281), Expect = 2.248e-167
Identity = 245/458 (53.49%), Postives = 335/458 (73.14%), Query Frame = 3 
Query:   66 MVAGQFIDYLTKFQVSNYAGVEDFADKFNFLFTVIVLLICTSIVTMKQYILKPISCYIST-ISGTNLLEYVENYCWVEGTIPISYDGKIPSTNEEWAELNKYKILYYQWVPFLLSLQAIMFYIPRLIWQIFCYNTTGTDIHHLIVSANQAVHSSDEARTKMVNYIAKTIEQMLYQHRDNRNGRLARFRRSLYKICCFCIMSKRQGTRLLCMYFIIKFLYLTNCILQLYFMKSFLGLN-EAGIFFGFKIMKNIINGQDWKSTLVFPRVGYCYVNVKNVGTTNALVAQCVLPVNMLNEKIFFFLWCWXXXXXXXXXXXXXXXXXXXXVYQRRRGFIYRFLKLNQQLKNCDEEKCMVVKFEHQFLRYDGVFLLKMISLNAGDIVAADIVCQLWKIFKSQYANRNF-LSDGSDDDENHGRTLIRLDNNNHSKPSFDKSNSLQSAFPSAPISPFDVENSHKKN 1430
            MV  +F+DY++KFQV+ Y GVEDFADKFNFL TV++LL+CT++VT+KQY++KPISCY++T I G NLL+YVENYCWV+GTIPI+Y GK+P T+  W E+ K+K+LYYQWVPF+L LQ IMFY+PR+IWQ+ CYN TGTDI HL++SANQAVH++D+ RTKM+ ++A+T+EQML+QHR+ RN   +  RR L+K C   ++SKR GTRL  +Y  IK LYL N + Q++ M++FLGL  +   FFG  I ++I++G+DW+ TLVFPRVGYC V V+++G +N +  QCVLPVNMLNE+I+ FLW WI  +A L  ISI  W  R S  + R  FI ++LKL + L   D  + MV KF+ QFLR DG+FLL+MI++NAGD++ +DIVCQLWKIFK++Y  R+  +SD   ++E H    ++L          ++  S   + P+AP  P D E    K+
Sbjct:    1 MVGSEFLDYISKFQVATYVGVEDFADKFNFLITVMILLLCTTVVTVKQYMMKPISCYMATDIGGKNLLDYVENYCWVQGTIPIAYAGKMPETDAAWEEMEKHKLLYYQWVPFVLGLQCIMFYVPRVIWQMICYNRTGTDIQHLVLSANQAVHATDDQRTKMIQHVARTLEQMLFQHREYRNDVWSHIRRRLWKTCSLLVVSKRLGTRLFAIYLFIKCLYLVNAVGQVFMMQTFLGLRYDNYSFFGIAIARDILSGKDWQRTLVFPRVGYCLVPVRHMGASNYVTGQCVLPVNMLNERIYVFLWFWIVLAATLTAISIPTWFMRMSYQKSRTCFIKKYLKLGEVLTKKD--RGMVEKFKRQFLRQDGIFLLRMIAINAGDLICSDIVCQLWKIFKTRYFFRDLTMSDEEQEEELH----VQLSRGTVEVTDLERCAS--DSTPTAP--PIDDEVEKMKS 448
[Close]
BLAST of Innexin vs. TrEMBL
Match: C1LF30 (Innexin OS=Schistosoma japonicum OX=6182 GN=inx PE=2 SV=1)

HSP 1 Score: 470.7 bits (1210), Expect = 2.998e-156
Identity = 236/458 (51.53%), Postives = 321/458 (70.09%), Query Frame = 3 
Query:   66 MVAGQFIDYLTKFQVSNYAGVEDFADKFNFLFTVIVLLICTSIVTMKQYILKPISCYIST-ISGTNLLEYVENYCWVEGTIPISYDGKIPSTNEEWAELNKYKILYYQWVPFLLSLQAIMFYIPRLIWQIFCYNTTGTDIHHLIVSANQAVHSSDEARTKMVNYIAKTIEQMLYQHRDNRNGRLARFRRSLYKICCFCIMSKRQGTRLLCMYFIIKFLYLTNCILQLYFMKSFLGLNEAG-IFFGFKIMKNIINGQDWKSTLVFPRVGYCYVNVKNVGTTNALVAQCVLPVNMLNEKIFFFLWCWXXXXXXXXXXXXXXXXXXXXVYQRRRGFIYRFLKLNQQLKNCDEEKCMVVKFEHQFLRYDGVFLLKMISLNAGDIVAADIVCQLWKIFKSQYANRNFL--SDGSDDDENHG----RTLIRLDNNNHSKPSFDKSNSLQSAFP--SAPISPFDV 1409
            M+  +F+DYL+KFQ++ Y GVEDFADKFNFL TV+VL+ICT+IVT+KQY++KPISCY++T + G NLL+YVENYCWV+GTIPISY G++P T+E WAEL K+K+LYYQWVPF+L LQ I+FY+PRLIWQ+ CYN  GTD+ HL++ ANQAVH+ D+ RTKMV ++AKT+EQ+L+Q R+  +G   R R  ++K     ++SKR GTRL  +Y  IK LYL N I Q++ M++FLGL       FG  I KNI++G DW+ T++FPRVG+C V +K+ G+ N   AQCVLPVNMLNE+I+ FLW WI  +A +  ISI  W  R S  + R  FI ++LKL +Q+   D  K M+ KF   FLR DGVFLL+MI++NAG+++ ++I+CQLW IF+ +Y  R+ L    G DD  + G    R ++     +  +    K  +  SA P   AP+   D 
Sbjct:    1 MIGTEFLDYLSKFQIATYVGVEDFADKFNFLITVMVLMICTTIVTVKQYMIKPISCYMATDLGGKNLLDYVENYCWVQGTIPISYSGRVPETDEGWAELEKHKLLYYQWVPFVLGLQCILFYLPRLIWQMICYNRVGTDVQHLVLCANQAVHAGDDQRTKMVQHLAKTLEQLLFQQREYSDGLWPRVRHRMWKCGYLFMISKRLGTRLFGIYLFIKCLYLVNAIGQIFMMQAFLGLKTNHYTLFGITISKNILSGLDWEVTMIFPRVGFCLVPLKHFGSNNYATAQCVLPVNMLNERIYMFLWFWIVLAATITAISIPAWFARMSYEKSRTRFIKKYLKLGEQVNKKD--KYMIEKFTRLFLRNDGVFLLRMIAINAGELICSEIICQLWHIFREKYFYRDLLHCKRGCDDKHHLGVRLSRGIVGFKKEHSKEDKHPKLEATASAPPPSDAPLGTLDT 456
[Close]
BLAST of Innexin vs. TrEMBL
Match: A0A3Q0KLG6 (Innexin OS=Schistosoma mansoni OX=6183 GN=inx PE=3 SV=1)

HSP 1 Score: 467.618 bits (1202), Expect = 6.202e-155
Identity = 236/445 (53.03%), Postives = 314/445 (70.56%), Query Frame = 3 
Query:   66 MVAGQFIDYLTKFQVSNYAGVEDFADKFNFLFTVIVLLICTSIVTMKQYILKPISCYIST-ISGTNLLEYVENYCWVEGTIPISYDGKIPSTNEEWAELNKYKILYYQWVPFLLSLQAIMFYIPRLIWQIFCYNTTGTDIHHLIVSANQAVHSSDEARTKMVNYIAKTIEQMLYQHRDNRNGRLARFRRSLYKICCFCIMSKRQGTRLLCMYFIIKFLYLTNCILQLYFMKSFLGLNEAGIFFGFKIMKNIINGQDWKSTLVFPRVGYCYVNVKNVGTTNALVAQCVLPVNMLNEKIFFFLWCWXXXXXXXXXXXXXXXXXXXXVYQRRRGFIYRFLKLNQQLKNCDEEKCMVVKFEHQFLRYDGVFLLKMISLNAGDIVAADIVCQLWKIFKSQYANRNFLSDGSDDDENH--GRTLIRLDNNNHSKPSFDKSNSLQSAFPSAP 1391
            M+   F+DYL+KFQV+ Y GVEDFADKFNFL TV+VL++CT+IVT+KQY++KPISCY++T + G NLL+YVENYCWV+GT+PI+Y G++P T+E WAEL K+K+LYYQWVPF+L LQ I+FY+PRLIWQ+ CYN  GTD+ HL++ ANQAVH++DE RTKMV ++AKT+EQ+L+Q R+  +G   R RR + K      +SKR GTRL  +Y  IK LYL N I Q++ M+SFLGL      FG  I +NI+ G DW+ T++FPRVG+C V +K+ G+ N   AQCVLPVNMLNE+I+ FLW WI  +A +  ISI  W  R S  + R  FI ++LKL +++   D  K MV KF   FLR DGVFLL+MI++NAG+++ ++IVCQLW IF+ +Y  R+      D D+ H  G  L R   N   + S +       A  SAP
Sbjct:    1 MIGTDFLDYLSKFQVATYVGVEDFADKFNFLITVMVLMLCTTIVTVKQYMMKPISCYMATDLGGKNLLDYVENYCWVQGTVPIAYSGRVPETDEGWAELEKHKLLYYQWVPFVLGLQCILFYLPRLIWQMICYNRVGTDVQHLVLCANQAVHANDEQRTKMVQHLAKTLEQLLFQQREYHHGLWPRVRRRMKKWGYLFFVSKRLGTRLFGIYLFIKCLYLLNAIGQIFMMQSFLGLKSNYTLFGVAISRNILAGLDWEVTMIFPRVGFCLVPLKHFGSNNYATAQCVLPVNMLNERIYMFLWFWIVLAATITAISIPTWFTRMSYEKSRTHFIKKYLKLGEKVSRKD--KYMVEKFTLLFLRNDGVFLLRMIAINAGELICSEIVCQLWHIFREKYFYRDLTRCKRDCDQMHHLGLKLSRGIVNLKERCSKENKQPRLEATASAP 443
[Close]
BLAST of Innexin vs. TrEMBL
Match: G4V9H2 (Innexin OS=Schistosoma mansoni OX=6183 GN=inx PE=3 SV=1)

HSP 1 Score: 466.848 bits (1200), Expect = 1.149e-154
Identity = 236/445 (53.03%), Postives = 314/445 (70.56%), Query Frame = 3 
Query:   66 MVAGQFIDYLTKFQVSNYAGVEDFADKFNFLFTVIVLLICTSIVTMKQYILKPISCYIST-ISGTNLLEYVENYCWVEGTIPISYDGKIPSTNEEWAELNKYKILYYQWVPFLLSLQAIMFYIPRLIWQIFCYNTTGTDIHHLIVSANQAVHSSDEARTKMVNYIAKTIEQMLYQHRDNRNGRLARFRRSLYKICCFCIMSKRQGTRLLCMYFIIKFLYLTNCILQLYFMKSFLGLNEAGIFFGFKIMKNIINGQDWKSTLVFPRVGYCYVNVKNVGTTNALVAQCVLPVNMLNEKIFFFLWCWXXXXXXXXXXXXXXXXXXXXVYQRRRGFIYRFLKLNQQLKNCDEEKCMVVKFEHQFLRYDGVFLLKMISLNAGDIVAADIVCQLWKIFKSQYANRNFLSDGSDDDENH--GRTLIRLDNNNHSKPSFDKSNSLQSAFPSAP 1391
            M+   F+DYL+KFQV+ Y GVEDFADKFNFL TV+VL++CT+IVT+KQY++KPISCY++T + G NLL+YVENYCWV+GT+PI+Y G++P T+E WAEL K+K+LYYQWVPF+L LQ I+FY+PRLIWQ+ CYN  GTD+ HL++ ANQAVH++DE RTKMV ++AKT+EQ+L+Q R+  +G   R RR + K      +SKR GTRL  +Y  IK LYL N I Q++ M+SFLGL      FG  I +NI+ G DW+ T++FPRVG+C V +K+ G+ N   AQCVLPVNMLNE+I+ FLW WI  +A +  ISI  W  R S  + R  FI ++LKL +++   D  K MV KF   FLR DGVFLL+MI++NAG+++ ++IVCQLW IF+ +Y  R+      D D+ H  G  L R   N   + S +       A  SAP
Sbjct:    1 MIGTDFLDYLSKFQVATYVGVEDFADKFNFLITVMVLMLCTTIVTVKQYMMKPISCYMATDLGGKNLLDYVENYCWVQGTVPIAYSGRVPETDEGWAELEKHKLLYYQWVPFVLGLQCILFYLPRLIWQMICYNRVGTDVQHLVLCANQAVHANDEQRTKMVQHLAKTLEQLLFQQREYHHGLWPRVRRRMKKWGYLFFVSKRLGTRLFGIYLFIKCLYLLNAIGQIFMMQSFLGLKSNYTLFGVAISRNILVGLDWEVTMIFPRVGFCLVPLKHFGSNNYATAQCVLPVNMLNERIYMFLWFWIVLAATITAISIPTWFTRMSYEKSRTHFIKKYLKLGEKVSRKD--KYMVEKFTLLFLRNDGVFLLRMIAINAGELICSEIVCQLWHIFREKYFYRDLTRCKRDCDQMHHLGLKLSRGIVNLKERCSKENKQPRLEATASAP 443
[Close]
BLAST of Innexin vs. Ensembl Medaka
Match: panx3 (pannexin 3 [Source:NCBI gene;Acc:101163377])

HSP 1 Score: 49.6766 bits (117), Expect = 7.627e-6
Identity = 48/204 (23.53%), Postives = 86/204 (42.16%), Query Frame = 3 
Query:  171 VLLICTSIVTMKQYILKP-ISCYISTISGTNLLEYVENYCWVEGTIPISYDGKIPSTNEEWAELNKYKILYYQWVPFLLSLQAIMFYIPRLIWQIFCYNTTGTDIHHLIVSANQAVHSSDEARTKMVNYIAKTIEQMLYQHRDNRNGRLARFRRSLYKICCFCIMSKRQGTRLLCMYFIIKFLYLT----NCILQLYF-MKSFL 764
            ++L+C + V  ++  L P ISC+  +        YV+ YCW         D  +    +      +  +  ++  P+ L   AI+ Y+P LIW+     T G+D+  +I   +++ + S      +++    T   + +Q    R  R   F   L +    C   K+    L+ M F+  FL LT     C+   YF + +FL
Sbjct:   49 LMLVCMAFV--REISLGPQISCFTPSNFTAKQASYVDTYCW---------DSLMHHEFDSDGNFEEQSLWVHKMFPYSLMAMAILMYLPALIWRQLVMPTLGSDLLFIIDELDKSYNRSIRLAQSILDMRQNTKNPLTFQAELQRAKRKRYFEYPLLERYLQC---KQNSYFLVSMLFLRGFLLLTFMTSACLYLTYFHLSAFL 238
[Close]
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000070656.1 (SMESG000070656.1)

HSP 1 Score: 815.839 bits (2106), Expect = 0.000e+0
Identity = 413/414 (99.76%), Postives = 413/414 (99.76%), Query Frame = 3 
Query:  201 MKQYILKPISCYISTISGTNLLEYVENYCWVEGTIPISYDGKIPSTNEEWAELNKYKILYYQWVPFLLSLQAIMFYIPRLIWQIFCYNTTGTDIHHLIVSANQAVHSSDEARTKMVNYIAKTIEQMLYQHRDNRNGRLARFRRSLYKICCFCIMSKRQGTRLLCMYFIIKFLYLTNCILQLYFMKSFLGLNEAGIFFGFKIMKNIINGQDWKSTLVFPRVGYCYVNVKNVGTTNALVAQCVLPVNMLNEKIFFFLWCWXXXXXXXXXXXXXXXXXXXXVYQRRRGFIYRFLKLNQQLKNCDEEKCMVVKFEHQFLRYDGVFLLKMISLNAGDIVAADIVCQLWKIFKSQYANRNFLSDGSDDDENHGRTLIRLDNNNHSKPSFDKSNSLQSAFPSAPISPFDVENSHKKNFRKV 1442
            MKQYILKPISCYISTISGTNLLEYVENYCWVEGTIPISYDGKIPSTNEEWAELNKYKILYYQWVPFLLSLQAIMFYIPRLIWQIFCYNTTGTDIHHLIVSANQAVHSSDEARTKMVNYIAKTIEQMLYQHRDNRNGRLARFRRSLYKICCFCIMSKRQGTRLLCMYFIIKFLYLTNCILQLYFMK FLGLNEAGIFFGFKIMKNIINGQDWKSTLVFPRVGYCYVNVKNVGTTNALVAQCVLPVNMLNEKIFFFLWCWIFSSAILLTISIIIWIFRTSVYQRRRGFIYRFLKLNQQLKNCDEEKCMVVKFEHQFLRYDGVFLLKMISLNAGDIVAADIVCQLWKIFKSQYANRNFLSDGSDDDENHGRTLIRLDNNNHSKPSFDKSNSLQSAFPSAPISPFDVENSHKKNFRKV
Sbjct:    1 MKQYILKPISCYISTISGTNLLEYVENYCWVEGTIPISYDGKIPSTNEEWAELNKYKILYYQWVPFLLSLQAIMFYIPRLIWQIFCYNTTGTDIHHLIVSANQAVHSSDEARTKMVNYIAKTIEQMLYQHRDNRNGRLARFRRSLYKICCFCIMSKRQGTRLLCMYFIIKFLYLTNCILQLYFMKCFLGLNEAGIFFGFKIMKNIINGQDWKSTLVFPRVGYCYVNVKNVGTTNALVAQCVLPVNMLNEKIFFFLWCWIFSSAILLTISIIIWIFRTSVYQRRRGFIYRFLKLNQQLKNCDEEKCMVVKFEHQFLRYDGVFLLKMISLNAGDIVAADIVCQLWKIFKSQYANRNFLSDGSDDDENHGRTLIRLDNNNHSKPSFDKSNSLQSAFPSAPISPFDVENSHKKNFRKV 414
[Close]
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000065083.1 (SMESG000065083.1)

HSP 1 Score: 514.227 bits (1323), Expect = 1.944e-177
Identity = 250/444 (56.31%), Postives = 334/444 (75.23%), Query Frame = 3 
Query:   66 MVAGQFIDYLTKFQVSNYAGVEDFADKFNFLFTVIVLLICTSIVTMKQYILKPISCYI-STISGTNLLEYVENYCWVEGTIPISYDGKIPSTNEEWAELNKYKILYYQWVPFLLSLQAIMFYIPRLIWQIFCYNTTGTDIHHLIVSANQAVHSSDEARTKMVNYIAKTIEQMLYQHRDNRNGRLARFRRSLYKICCFCIMSKRQGTRLLCMYFIIKFLYLTNCILQLYFMKSFLGLNEAGIF-FGFKIMKNIINGQDWKSTLVFPRVGYCYVNVKNVGTTNALVAQCVLPVNMLNEKIFFFLWCWXXXXXXXXXXXXXXXXXXXXVYQRRRGFIYRFLKLNQQLKNCDEEKCMVVKFEHQFLRYDGVFLLKMISLNAGDIVAADIVCQLWKIFKSQYANRNFLSDGSDDDENHGRTLIRLDNNNHSKPSFDKSNSLQSAFPSAP 1391
            MVA +F+DYL+K QVS   G+ED  D+ NF F+VIVL++C  IVT+KQY+ KPISCY+ + I G+NLL YVEN CWV+GTI +S   K PST+EEW  L K+K+LYYQWVPF+L LQ IMFY+P+L+WQI CYN TGTDI HL+VSANQAVHSSDEAR+KMV+Y++KT+EQ+LYQHRD+R+G+LA+FRR ++    F + SKR GT L+  Y ++K  Y+ N  +QL  M+ FLG ++  +  FG ++  NI +G DWK+TL+FPRV YC+V V ++G  N++VAQCVLPVNMLNE+I+FFLWCWI     L  +SI IWI R    + RR FI +FL +++++    +E  ++ KFE QFLR+DG+FLLKMISLNAGDI+ ++IVCQLW I+K+ Y NRNFL+DGSD+D++  RT+I+L   N+     DK++      PSAP
Sbjct:    1 MVASEFLDYLSKLQVSTNVGLEDLPDRLNFTFSVIVLMVCILIVTVKQYVFKPISCYLPNNIGGSNLLSYVENLCWVQGTIALSNQAKFPSTDEEWKNLEKHKMLYYQWVPFMLGLQCIMFYVPKLVWQIICYNRTGTDIQHLVVSANQAVHSSDEARSKMVSYLSKTLEQLLYQHRDHRSGKLAKFRRKIHNSVGFLMCSKRIGTWLVSSYLLLKLSYVANGFIQLIIMQKFLGFSDFNLLTFGIEVGNNIWSGTDWKTTLIFPRVSYCFVKVTHLGVINSMVAQCVLPVNMLNERIYFFLWCWILIVLSLTILSIPIWILRILCIKYRRHFIRQFLIISEEITKDQKENYLLAKFESQFLRHDGIFLLKMISLNAGDIITSEIVCQLWNIYKTNYVNRNFLNDGSDEDDDKSRTMIKLGFLNNKLA--DKTS------PSAP 436
[Close]
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000070496.1 (SMESG000070496.1)

HSP 1 Score: 394.815 bits (1013), Expect = 4.100e-130
Identity = 219/484 (45.25%), Postives = 299/484 (61.78%), Query Frame = 3 
Query:   66 MVAGQFIDYLTKFQVSNYAGVEDFADKFNFLFTVIVLLICTSIVTMKQYILKPISCYIST-ISGTNLLEYVENYCWVEGTIPISYDGKIPSTNEEWAELNKYKILYYQ----------WVP--------FLLSLQ----------------AIMFYIPRLIWQIFCYNTTGTDIHHLIVSANQAVHSSDEARTKMVNYIAKTIEQMLYQHRDNRNGRLARFRRSLYKICCFCIMSKRQGTRLLCMYFIIKFLYLTNCILQLYFMKSFLGLNEAGIFFGFKIMKNIINGQDWKSTLVFPRVGYCYVNVKNVGT-TNALVAQCVLPVNMLNEKIFFFLWCWXXXXXXXXXXXXXXXXXXXXVYQRRRGFIYRFLKLNQQLKNCD-EEKCMVVKFEHQFLRYDGVFLLKMISLNAGDIVAADIVCQLWKIFKSQYANR-----NFLSDGSDDDENHGRTLIRLDNNNHSKPSFDKSNSLQSAFPSAP 1391
            M A QF D L KFQ + Y GV+D ADK NFL TVI+LL+C S+VT++QY+LKPISCY+ST I G NLL+YVEN+CWV GTIPISY+G  P+T  EW E+ K+KIL ++          W P        +L S++                A +F++P L+W + C N TGTDI H+I SANQAVHS +EA+ KM  YIAKTIE MLYQ++    G      +++Y  C FCI SKR GT ++  YF +K LY+ N + QLY MK FLG  E+  F G+K++ N++ G+DW+ TL+FPR+ +C V ++++G   N ++AQCVLPVNMLNEKI+ FLW WI    ++  IS++ W+++    Q    FI   L LN+++K  D   + +V KF   FLRYDGVFLL+M+SLNAGD+V  ++VC LW +F  +Y  R     N+  +   D        +  D  N S      +  + S  PSAP
Sbjct:    1 MAANQFFDSLNKFQWNTYVGVDDLADKLNFLLTVIILLVCISVVTVRQYVLKPISCYLSTDIGGVNLLDYVENFCWVHGTIPISYNGSTPTTEIEWQEMEKFKILMWKTRVICEARAIWKPQTKIRLIFWLKSIKNSFYIINGCHLFSVFSAFLFHLPHLLWTLICRNQTGTDIQHVITSANQAVHSGEEAKEKMTIYIAKTIEHMLYQNQCKNIGIRKMISKNIYSNCAFCIASKRIGTSVVIGYFTVKLLYIGNAVGQLYLMKFFLGF-ESFSFLGYKVLHNLLAGKDWEITLIFPRIAFCLVKIRHLGERNNGVLAQCVLPVNMLNEKIYIFLWHWIMLCGVISFISLLHWMYKLGQMQNNSTFIRTQLLLNEKIKRYDINHRNLVDKFTKSFLRYDGVFLLRMMSLNAGDMVTGEVVCHLWIMFNEKYNYRCTSKMNYEINSDGDCSPSAHCHLVSDRGNIS------NGYVGSNRPSAP 477
[Close]
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000080788.1 (SMESG000080788.1)

HSP 1 Score: 383.259 bits (983), Expect = 1.838e-126
Identity = 193/403 (47.89%), Postives = 270/403 (67.00%), Query Frame = 3 
Query:   66 MVAGQFIDYLTKFQVSNYAGVEDFADKFNFLFTVIVLLICTSIVTMKQYILKPISCYISTI-SGTNLLEYVENYCWVEGTIPISYDGKIPSTNEEWAELNKYK-ILYYQWVPFLLSLQAIMFYIPRLIWQIFCYNTTGTDIHHLIVSANQAVHSSDEARTKMVNYIAKTIEQMLYQHRDNRNGRLARFRRSLYKICCFCIMSKRQGTRLLCMYFIIKFLYLTNCILQLYFMKSFLGLNEAGIFFGFKIMKNIINGQDWKSTLVFPRVGYCYV-NVKNVGTTNALVAQCVLPVNMLNEKIFFFLWCWXXXXXXXXXXXXXXXXXXXXVYQRRRGFIYRFLKLNQQLKNCDEEKCMVVKFEHQFLRYDGVFLLKMISLNAGDIVAADIVCQLWKIFKSQYANRNF 1265
            MVA +F++ + +F++S Y G+EDFADK +FLF+V +L++   +VT+K Y+ KP++CY +T   G+N   Y+ENYCWV GTI       IP  + +WA  +  + I YYQWVPF+L LQ  MFYIP++IWQI CYN +GT++  ++  AN A ++    R   +  IA+TIE ML+QHRD R G  A+ RR +Y  C FC+ SK  GT L+  Y +IKFLY  N I QL+ MK FLG N +   FG+ ++ N+I+G++W  T +FPRV YCYV N+K+VG  N  VAQC LPVNMLNEKI+ FLW W+    I+  ISI +W +R +   RR  FI RFL ++Q  +  D  K M+  F  +FLR+DGVFL++M+ +NAGDI+ ADIV +L +I+K  Y + +F
Sbjct:    1 MVAEEFLNLIGQFKISTYVGIEDFADKLSFLFSVTLLILSMMVVTIKSYLFKPLACYTATAPGGSNFENYLENYCWVHGTITFLPGEDIPQNDVDWARADDTRRINYYQWVPFILGLQCFMFYIPKIIWQIICYNKSGTNLESIVNDANAANNTPPVERKDKIERIARTIEDMLFQHRDYRQGNFAKLRRKIYNTCNFCVFSKHMGTWLILSYILIKFLYGLNVIGQLFIMKKFLGFNNSTSSFGYTVLSNMISGKEWHQTGIFPRVTYCYVRNIKHVGVANKYVAQCALPVNMLNEKIYVFLWFWMVLVGIVTAISIPLWFYRMAFLSRRSKFIKRFLMMHQNYERSD--KPMINNFIEEFLRHDGVFLVRMLFINAGDIITADIVNRLLEIYKENYKHLDF 401
[Close]
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000081749.1 (SMESG000081749.1)

HSP 1 Score: 334.339 bits (856), Expect = 6.551e-108
Identity = 173/401 (43.14%), Postives = 260/401 (64.84%), Query Frame = 3 
Query:   81 FIDYLTKFQVSNYAGVEDFADKFNFLFTVIVLLICTSIVTMKQYILKPISCYISTI-SGTNLLEYVENYCWVEGTIPISYDGKIPSTNEEW--AELNKYKILYYQWVPFLLSLQAIMFYIPRLIWQIFCYNTTGTDIHHLIVSANQAVHSSDEARTKMVNYIAKTIEQMLYQHRDNRNGRLARFRRSLYKICCFCIMSKRQGTRLLCMYFIIKFLYLTNCILQLYFMKSFL--GLNEAGIFFGFKIMKNIINGQDWKSTLVFPRVGYCYV-NVKNVGTTNALVAQCVLPVNMLNEKIFFFLWCWXXXXXXXXXXXXXXXXXXXXVYQRRRGFIYRFLKLNQQLKNCDEEKCMVVKFEHQFLRYDGVFLLKMISLNAGDIVAADIVCQLWKIFKSQYANRNF 1265
            F+   T FQ   Y G+ED ADK +FLF+VI+L++C+ IV+ KQYI   ISCYI  + SG +L +YV+NYCWV GTIP   +  +P T +EW  A+ ++ KI YYQWVPF+L LQ ++FY+PRLIW+   YN +G D+  L+VSA +A +   E R + +  +AK +E +  Q R   + +    R+ +  ICC     +R G   + +Y +IK LYLTN I Q+  M++FL  G+++    FG+ I+K+I++G+ W   L+FPRV +C++ ++  V   N  +AQC LP+NMLNEKI+ FLW W      L  ISI +W++R + +++R+ FI RFLK+        ++K ++ +F  QFLR+DG+F+L +ISLNAGD++A DIV +LW+I+   Y   +F
Sbjct:    4 FLSQFTAFQAGKYVGIEDAADKASFLFSVIILVVCSVIVSTKQYITADISCYIPVVLSGVDLDKYVKNYCWVHGTIPFYANETLPQTKDEWIIADASR-KINYYQWVPFVLGLQGVLFYLPRLIWKTIIYNLSGNDLEGLVVSAKKASNQVGEIRKETILQVAKCLEDLFLQRRVLGHTKFPVLRQKMSLICC----GRRTGVFFISLYIVIKLLYLTNAICQIILMQNFLKYGVSKLNAAFGWTILKDILSGKQWNDNLLFPRVSFCFISDISTVTHKNHHIAQCALPINMLNEKIYIFLWFWTVGVLFLTIISIPLWLYRMTFFRKRKDFIKRFLKIKSAYTK--DKKNLISQFVEQFLRHDGIFILHIISLNAGDLIATDIVSELWEIYNKYYLKIDF 397
The following BLAST results are available for this feature:
BLAST of Innexin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
inx-12.737e-6532.70Innexin [Source:UniProtKB/TrEMBL;Acc:Q17394][more]
inx-11.194e-6434.11Innexin [Source:UniProtKB/TrEMBL;Acc:Q17394][more]
inx-11.194e-6434.11Innexin [Source:UniProtKB/TrEMBL;Acc:Q17394][more]
unc-95.780e-5831.52Innexin unc-9 [Source:UniProtKB/Swiss-Prot;Acc:O0... [more]
unc-71.948e-5731.37Innexin unc-7 [Source:UniProtKB/Swiss-Prot;Acc:Q0... [more]
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BLAST of Innexin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
shakB2.733e-2027.55gene:FBgn0085387 transcript:FBtr0112571[more]
ogre2.148e-1925.69gene:FBgn0004646 transcript:FBtr0071037[more]
ogre2.148e-1925.69gene:FBgn0004646 transcript:FBtr0334881[more]
ogre2.148e-1925.69gene:FBgn0004646 transcript:FBtr0309875[more]
ogre2.148e-1925.69gene:FBgn0004646 transcript:FBtr0071036[more]
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BLAST of Innexin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|O01393|UNC9_CAEEL7.353e-5731.52Innexin unc-9 OS=Caenorhabditis elegans OX=6239 GN... [more]
sp|Q03412|UNC7_CAEEL8.757e-5631.54Innexin unc-7 OS=Caenorhabditis elegans OX=6239 GN... [more]
sp|Q23157|INX11_CAEEL1.940e-4929.92Innexin-11 OS=Caenorhabditis elegans OX=6239 GN=in... [more]
sp|Q27295|EAT5_CAEEL6.797e-4927.76Innexin eat-5 OS=Caenorhabditis elegans OX=6239 GN... [more]
sp|A8WVX4|INX19_CAEBR5.538e-4830.69Innexin-19 OS=Caenorhabditis briggsae OX=6238 GN=i... [more]
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BLAST of Innexin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
G7YJJ03.374e-16953.39Innexin OS=Clonorchis sinensis OX=79923 GN=inx PE=... [more]
A0A4S2LNY22.248e-16753.49Innexin OS=Opisthorchis felineus OX=147828 GN=inx ... [more]
C1LF302.998e-15651.53Innexin OS=Schistosoma japonicum OX=6182 GN=inx PE... [more]
A0A3Q0KLG66.202e-15553.03Innexin OS=Schistosoma mansoni OX=6183 GN=inx PE=3... [more]
G4V9H21.149e-15453.03Innexin OS=Schistosoma mansoni OX=6183 GN=inx PE=3... [more]
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BLAST of Innexin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
panx37.627e-623.53pannexin 3 [Source:NCBI gene;Acc:101163377][more]
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BLAST of Innexin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000070656.10.000e+099.76SMESG000070656.1[more]
SMESG000065083.11.944e-17756.31SMESG000065083.1[more]
SMESG000070496.14.100e-13045.25SMESG000070496.1[more]
SMESG000080788.11.838e-12647.89SMESG000080788.1[more]
SMESG000081749.16.551e-10843.14SMESG000081749.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30019735 ID=SMED30019735|Name=Innexin|organism=Schmidtea mediterranea sexual|type=transcript|length=2135bp
CTCTTCCGATCTCAAAATTAATGAGTCATCCTTCAATAAAGTCTTTTTAG
ATTTCCACTACTTTTATGGTCGCCGGTCAATTTATTGATTATCTCACAAA
ATTTCAAGTGAGCAATTATGCCGGAGTTGAAGATTTTGCTGATAAATTTA
ATTTCCTATTCACTGTTATAGTTTTACTAATATGCACAAGTATTGTAACA
ATGAAGCAATATATTCTCAAGCCAATATCTTGCTATATATCCACGATTAG
TGGGACCAATTTACTTGAATATGTGGAAAACTATTGCTGGGTTGAAGGAA
CGATTCCGATTTCCTATGATGGCAAAATACCATCTACCAATGAAGAATGG
GCTGAGTTAAATAAATACAAAATATTATATTATCAATGGGTACCATTTCT
ACTTTCATTGCAAGCGATTATGTTTTATATTCCTCGGTTAATATGGCAAA
TATTTTGCTACAATACTACTGGAACTGATATCCATCATCTTATAGTGAGT
GCCAATCAAGCTGTCCATTCCAGTGATGAGGCCAGAACGAAAATGGTCAA
TTATATTGCTAAAACTATAGAACAAATGCTGTATCAACATCGTGATAACC
GAAATGGTAGATTAGCTAGATTTCGTAGATCTCTTTATAAAATTTGCTGC
TTTTGTATCATGAGCAAGCGCCAAGGAACCAGATTATTGTGTATGTACTT
CATAATAAAATTTCTTTATCTCACAAACTGTATTTTGCAACTATATTTCA
TGAAAAGTTTTCTTGGACTGAATGAAGCCGGCATATTTTTTGGTTTCAAA
ATAATGAAAAACATAATAAACGGTCAGGATTGGAAATCAACACTTGTGTT
TCCCAGAGTCGGCTATTGTTATGTTAACGTTAAAAATGTAGGCACTACGA
ATGCTCTAGTTGCTCAATGTGTATTGCCTGTCAACATGTTAAATGAGAAA
ATCTTTTTCTTTCTTTGGTGCTGGATATTTTCATCGGCAATTTTGTTAAC
AATCAGTATAATCATATGGATATTTCGGACGAGTGTATATCAGAGGCGTC
GTGGATTTATTTACAGGTTTCTGAAATTGAATCAGCAATTGAAAAACTGT
GATGAAGAAAAGTGCATGGTTGTGAAATTTGAACATCAATTTCTCAGATA
TGATGGAGTCTTTCTATTGAAAATGATCTCTTTGAATGCTGGCGACATTG
TTGCTGCAGATATTGTCTGTCAACTGTGGAAAATATTCAAATCGCAATAC
GCTAATCGGAATTTTCTAAGCGATGGTTCCGATGATGATGAAAATCATGG
ACGGACGCTCATTCGACTTGACAATAATAATCACAGCAAACCTAGCTTTG
ACAAAAGTAACTCTTTACAATCTGCATTTCCTTCTGCGCCTATATCTCCA
TTTGATGTTGAAAATTCACATAAAAAAAACTTCAGAAAAGTTATTTCTAG
TGAATCTTGATGAATAATATTTGAACAGAATTTTTTAATGGATTTTTTTT
AGAATTTTTATATTTATATTTGGTTTGTTTTTATTTTTTTTGTATTTAAT
ATTAAAAATAATTGTCCAAAGATAATATATACAAAATTTGAATTATTTTT
AGTGTGAAATGTGTGAACTTTTTATCGATTAGTCAAGTGAAGTAGTCTGG
CATTGTTGCCATGGATGGCATGTGAAAGCAAAGTTACCGATTTCTTTTTG
ACAATCCCTATTTTATGATTTGTGTATAATATAGTTGGTCATTCTTCTAT
AGTGCAGCGCTTAGTATTGGATGTAATATAACCATCAACCAATCAGGGGA
CTCTGGAACATATTGTCCTACTCAAATGCACATTTTGTCTGAGTCAAACA
AATACTCTGCCTAATAATGATCTCTATGATCCGGCAGAATTGGTTTCTAA
AAATCTATATTTGTACATGTATTTACCCTTTTGCACTATTCCCGACAGAT
CACGTCTATATAGACCAATTAATATAAAGTGTACACTTTAAATAATTTAC
TTTTTTGTATTTGCACATTTTGTCTCAGTAAGTAACAGCTCATTTAGTTA
CTGCCGCTATTCCTGATATGTCAATTTTTTTAGTTGTTGCAACAGAGAGC
TCTTTATGTACTGCAAATTTCAGTGTTAATGAAGC
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protein sequence of SMED30019735-orf-1

>SMED30019735-orf-1 ID=SMED30019735-orf-1|Name=SMED30019735-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=465bp
MVAGQFIDYLTKFQVSNYAGVEDFADKFNFLFTVIVLLICTSIVTMKQYI
LKPISCYISTISGTNLLEYVENYCWVEGTIPISYDGKIPSTNEEWAELNK
YKILYYQWVPFLLSLQAIMFYIPRLIWQIFCYNTTGTDIHHLIVSANQAV
HSSDEARTKMVNYIAKTIEQMLYQHRDNRNGRLARFRRSLYKICCFCIMS
KRQGTRLLCMYFIIKFLYLTNCILQLYFMKSFLGLNEAGIFFGFKIMKNI
INGQDWKSTLVFPRVGYCYVNVKNVGTTNALVAQCVLPVNMLNEKIFFFL
WCWIFSSAILLTISIIIWIFRTSVYQRRRGFIYRFLKLNQQLKNCDEEKC
MVVKFEHQFLRYDGVFLLKMISLNAGDIVAADIVCQLWKIFKSQYANRNF
LSDGSDDDENHGRTLIRLDNNNHSKPSFDKSNSLQSAFPSAPISPFDVEN
SHKKNFRKVISSES*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000101muscle cell
PLANA:0000142posterior region of the whole animal
PLANA:0002056medial muscle cell
Vocabulary: cellular component
TermDefinition
GO:0005921gap junction
GO:0005886plasma membrane
GO:0016020membrane
GO:0016021integral component of membrane
GO:0030054cell junction
Vocabulary: INTERPRO
TermDefinition
IPR000990Innexin
Vocabulary: biological process
TermDefinition
GO:0006810transport
GO:0006811ion transport