Voltage-dependent calcium channel

Overview


Name	Voltage-dependent calcium channel
Smed ID	SMED30019733
Length (bp)	6014

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Voltage-dependent calcium channel (SMED30019733) t-SNE clustered cells

Violin plots show distribution of expression levels for Voltage-dependent calcium channel (SMED30019733) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Voltage-dependent calcium channel (SMED30019733) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Voltage-dependent calcium channel (SMED30019733) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30019733

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 6

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
protonephridia	SMED30019733	SMESG000076454.1 SMESG000076415.1	dd_Smed_v4_7314_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30019733	SMESG000076415.1	Contig35701	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30019733	SMESG000076415.1	Contig35701	newmark_ests	PMID:29674431 Fincher et al., 2018
head region	SMED30019733	SMESG000076454.1 SMESG000076415.1	dd_Smed_v6_7314_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
testis	SMED30019733	SMESG000076415.1	Contig6123	uc_Smed_v2	PMID:28434803 Rouhana et al., 2017
testis	SMED30019733	SMESG000076415.1	Contig6123	newmark_ests	PMID:28434803 Rouhana et al., 2017

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Homology

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BLAST of Voltage-dependent calcium channel vs. Ensembl Human
Match: NALCN (sodium leak channel, non-selective [Source:HGNC Symbol;Acc:HGNC:19082])

HSP 1 Score: 1481.85 bits (3835), Expect = 0.000e+0
Identity = 859/1920 (44.74%), Postives = 1185/1920 (61.72%), Query Frame = 2

Query:  164 ERKTSHTRETQPTLPGVEFATDDA-GDLTSVNWVYTTWARCAFKIXXXXXXXXXXXNTPETFKEYKWLFYVTYLLDIVVALLFTAEMFTKMKIKGIIRPSPYVIVRHLFFVKVSNNIENKRPHAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANS--IEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWLVKNVFIAILTETFAEIRVQFQQMWSPKNQTDADSS-KIFQTDGQR-WKLVPVYESKPHGLAPKLFQEIVLKSTAFNVIIMLLVLANAIVAAGLHFNHDELT-QTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHCM--WYRTQLTYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEPKFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPNDWAQQLFSTFSGIYFILINLIFSFAFMSMFQILTQKGWVIVMHDTMDMAKHRGLNALVAIYFVFYHLFVTLIVLSLFVAVILDNLELEEDIKKLKQLKLREMSAETQQKLPMRLRIFEKFPNRPQMIKPARLLSDFLIPKIRDSFMRQFAQLPTLEEENESDEMIAAAVSGVGVSSLPRALSIEIKRQ-------------IRGLKGNDKLNAIIYLINESNKTRMIE-----QPIIYPTRSLLSTQHQIRTERRNLRNRMAATTMSINQKPRLNGEIRNMDFETNRKTEEANHFDIKILQQKAEQAEIKRNQQVDDLRENHPYFDKPLFTIGRESQFRQLCRMLVEAQY---KPDINSENPEKQTFYKLQKFFGLVTYLDWVMIFVTTTSCISMAFETPTKRVMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTK-----LKLSGDSPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVGRINVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVDQRRWLDLKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRE-NFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFIKAFYVRF-LLRLIPKDRVGFDFTKKKDQQLFKEMCYEVELLRGGKDKEVSFHDVLTMLAYRSVDISKTXXXXXXXXXXXXXXXXXXXXXRQTIATWIERCIFRNRQKHGDLKFGLRESNEMVIPIFDDKKEGLGLDRSRKISSGAYQTKFLSLPTLDGRQNTSDGSLPSSGITIGRLNDHLKNQPMGFKRRRSVKKNSSTNQTLTEVSEDELNDELNDIVPTQDPDLTPNQ--LPSLSDSHVPIENSISS-----------RSEDKHLTELVD-ADC-HEVKSWWHVQINTD 5770
            +RK S   E QP     +F  D++  D   + W+   W     +I A++S+ SV  NTP TF+ Y  L YVT+ LD ++  L+TAEM  KM I+GI+                      K   +Y++  W  FD  MV CLW+S+ +Q FE+  ++   +P             +G+L   R PRPLI+ R  R + +F LP+TR+  IL RS  Q+++V++FLLFF+ LY ILGVQ FG    +HCV+      ++    LAIPD+ C+P+ + G  CP   KC+ + +      E GY+GF     S FTVY+AASQEGWVF+MYRA+D  P+W+   YFI++IFFLAWLVKNVFIA++ ETFAEIRVQFQQMW  ++ T + ++ ++F  D    W+LV V  +KP G AP   Q++ ++S+ F++ I+ +V  + IVAA  ++  +    Q + FY AE+ FT+LF++EA+ KIWCLG+  Y   SLHKFE +L +GTT+H     Y +Q TYFQVLR+ RL+K SP LEDF +KIFG GKKLG L++FT+ LLI+ S++SLQ+FC ++    + DR                                          F+TF              AFMSMFQILTQ+GWV VM  T++   H     +VAIYF+ YHLF TLI+LSLFVAVILDNLEL+ED+KKLKQLK  E +A+T++KLP+RLRIFEKFPNRPQM+K ++L SDF +PKIR+SFM+QF     ++ + +    +  ++     SS   +    I+               IR     +K  A+  ++    + RM+      QP     RS+LS QH IR ERR+LR+   + +  I++   L    ++       +  +    +IK++Q+K EQAE+KR  Q ++LRENHPYFDKPLF +GRE +FR  CR++V A++   K D  +   +   +++L    GLVTYLDWVMI VT  SCISM FE+P +RVM+   L++AEY+F + M+IE+ LK++A+G  FTP AV+RDFGGV+D FIY++ +IF+ +M +   + + SG Q+LM+LRCLRPLRIF LVP MR+VV EL  GF+EI +VS+LL+  M  FA +GV +F GKLA CNDP    ++DC G+F   +SV+K     L+     P F VPRVWANPRNFNFDN+GNAML LFEVLSL+GWVE+RDVI  RVG I+ IYIH+FVF+GC+IGLTLFVGVVIAN++ENKGTALLTVDQRRW DLK R+K+ QPLH+PPRP           DN+              R  +YD+TQH +FKR  A++VL   + L   W+ +D   +     LA+ +V +TFIF +E  +KI A+S  G+WQS+RN YD++VT L ++WV +H ++ + +   +     G   ++ RFFSI GKHVTLKML+ TV++SM+KS F+I+ MFLL+L YA AG++LFG+VKYGEN+ RHANF +  ++I +LFRIVTGEDWNKIMHDCMVQPPFCT  E  +W +DCGN+  +L+YFCSFY++I YIMLN+LVAII+ENFSLFYS +ED ++SYND+R+FQ  WN +D  R+G I  F V+F L  L  +  V  D    KD+ LFK MCYE+E L  G D  V+FHDVL+ML+YRSVDI K+LQLEELLARE+LEY IEEEVA+QTI  W+++C+ R R K        ++S  ++  + + +++ L              ++FL+ P+++  Q + D +  S                    +  S++  +S+ Q L   +  +      D      P     Q  LPS      PI +S+SS           +S    +  + D A C  EVK WW  Q+  +
Sbjct:    3 KRKQSSRVEAQPV---TDFGPDESLSDNADILWINKPWVHSLLRICAIISVISVCMNTPMTFEHYPPLQYVTFTLDTLLMFLYTAEMIAKMHIRGIV----------------------KGDSSYVKDRWCVFDGFMVFCLWVSLVLQVFEIADIVDQMSP-------------WGML---RIPRPLIMIRAFRIYFRFELPRTRITNILKRSGEQIWSVSIFLLFFLLLYGILGVQMFGT-FTYHCVVNDTKPGNVTWNSLAIPDTHCSPELEEGYQCPPGFKCMDLEDLGLSRQELGYSGFNEIGTSIFTVYEAASQEGWVFLMYRAIDSFPRWRSYFYFITLIFFLAWLVKNVFIAVIIETFAEIRVQFQQMWGSRSSTTSTATTQMFHEDAAGGWQLVAVDVNKPQGRAPACLQKM-MRSSVFHMFILSMVTVDVIVAASNYYKGENFRRQYDEFYLAEVAFTVLFDLEALLKIWCLGFTGYISSSLHKFELLLVIGTTLHVYPDLYHSQFTYFQVLRVVRLIKISPALEDFVYKIFGPGKKLGSLVVFTASLLIVMSAISLQMFCFVE----ELDR------------------------------------------FTTFPR------------AFMSMFQILTQEGWVDVMDQTLNAVGHM-WAPVVAIYFILYHLFATLILLSLFVAVILDNLELDEDLKKLKQLKQSEANADTKEKLPLRLRIFEKFPNRPQMVKISKLPSDFTVPKIRESFMKQF-----IDRQQQDTCCLLRSLPTTSSSSCDHSKRSAIEDNKYIDQKLRKSVFSIRARNLLEKETAVTKILRACTRQRMLSGSFEGQPA--KERSILSVQHHIRQERRSLRH--GSNSQRISRGKSLETLTQDHSNTVRYRNAQREDSEIKMIQEKKEQAEMKRKVQEEELRENHPYFDKPLFIVGREHRFRNFCRVVVRARFNASKTDPVTGAVKNTKYHQLYDLLGLVTYLDWVMIIVTICSCISMMFESPFRRVMHAPTLQIAEYVFVIFMSIELNLKIMADGLFFTPTAVIRDFGGVMDIFIYLVSLIFLCWMPQ--NVPAESGAQLLMVLRCLRPLRIFKLVPQMRKVVRELFSGFKEIFLVSILLLTLMLVFASFGVQLFAGKLAKCNDPNIIRREDCNGIFRINVSVSKNLNLKLRPGEKKPGFWVPRVWANPRNFNFDNVGNAMLALFEVLSLKGWVEVRDVIIHRVGPIHGIYIHVFVFLGCMIGLTLFVGVVIANFNENKGTALLTVDQRRWEDLKSRLKIAQPLHLPPRP-----------DNDGF------------RAKMYDITQHPFFKRTIALLVLAQSVLLSVKWDVEDPVTVP----LATMSVVFTFIFVLEVTMKIIAMSPAGFWQSRRNRYDLLVTSLGVVWVVLHFALLNAYTYMM-----GACVIVFRFFSICGKHVTLKMLLLTVVVSMYKSFFIIVGMFLLLLCYAFAGVVLFGTVKYGENINRHANFSSAGKAITVLFRIVTGEDWNKIMHDCMVQPPFCTPDEFTYWATDCGNYAGALMYFCSFYVIIAYIMLNLLVAIIVENFSLFYSTEEDQLLSYNDLRHFQIIWNMVDDKREGVIPTFRVKFLLRLLRGRLEVDLD----KDKLLFKHMCYEMERLHNGGD--VTFHDVLSMLSYRSVDIRKSLQLEELLAREQLEYTIEEEVAKQTIRMWLKKCLKRIRAKQ-------QQSCSIIHSLRESQQQEL--------------SRFLNPPSIETTQPSEDTNANS--------------------QDNSMQPETSSQQQLLSPTLSDRGGSRQDAADAGKPQRKFGQWRLPSAPK---PISHSVSSVNLRFGGRTTMKSVVCKMNPMTDAASCGSEVKKWWTRQLTVE 1727

[Close]

BLAST of Voltage-dependent calcium channel vs. Ensembl Human
Match: NALCN (sodium leak channel, non-selective [Source:HGNC Symbol;Acc:HGNC:19082])

HSP 1 Score: 1408.66 bits (3645), Expect = 0.000e+0
Identity = 763/1627 (46.90%), Postives = 1044/1627 (64.17%), Query Frame = 2

Query:  164 ERKTSHTRETQPTLPGVEFATDDA-GDLTSVNWVYTTWARCAFKIXXXXXXXXXXXNTPETFKEYKWLFYVTYLLDIVVALLFTAEMFTKMKIKGIIRPSPYVIVRHLFFVKVSNNIENKRPHAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANS--IEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWLVKNVFIAILTETFAEIRVQFQQMWSPKNQTDADSS-KIFQTDGQR-WKLVPVYESKPHGLAPKLFQEIVLKSTAFNVIIMLLVLANAIVAAGLHFNHDELT-QTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHCM--WYRTQLTYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEPKFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPNDWAQQLFSTFSGIYFILINLIFSFAFMSMFQILTQKGWVIVMHDTMDMAKHRGLNALVAIYFVFYHLFVTLIVLSLFVAVILDNLELEEDIKKLKQLKLREMSAETQQKLPMRLRIFEKFPNRPQMIKPARLLSDFLIPKIRDSFMRQFAQLPTLEEENESDEMIAAAVSGVGVSSLPRALSIEIKR-------------QIRGLKGNDKLNAIIYLINESNKTRMIE-----QPIIYPTRSLLSTQHQIRTERRNLRNRMAATTMSINQKPRLNGEIRNMDFETNRKTEEANHFDIKILQQKAEQAEIKRNQQVDDLRENHPYFDKPLFTIGRESQFRQLCRMLVEAQY---KPDINSENPEKQTFYKLQKFFGLVTYLDWVMIFVTTTSCISMAFETPTKRVMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTK-----LKLSGDSPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVGRINVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVDQRRWLDLKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRE-NFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGF 4939
            +RK S   E QP     +F  D++  D   + W+   W     +I A++S+ SV  NTP TF+ Y  L YVT+ LD ++  L+TAEM  KM I+GI+                      K   +Y++  W  FD  MV CLW+S+ +Q FE+  ++   +P             +G+L   R PRPLI+ R  R + +F LP+TR+  IL RS  Q+++V++FLLFF+ LY ILGVQ FG    +HCV+      ++    LAIPD+ C+P+ + G  CP   KC+ + +      E GY+GF     S FTVY+AASQEGWVF+MYRA+D  P+W+   YFI++IFFLAWLVKNVFIA++ ETFAEIRVQFQQMW  ++ T + ++ ++F  D    W+LV V  +KP G AP   Q++ ++S+ F++ I+ +V  + IVAA  ++  +    Q + FY AE+ FT+LF++EA+ KIWCLG+  Y   SLHKFE +L +GTT+H     Y +Q TYFQVLR+ RL+K SP LEDF +KIFG GKKLG L++FT+ LLI+ S++SLQ+FC ++    + DR                                          F+TF              AFMSMFQILTQ+GWV VM  T++   H     +VAIYF+ YHLF TLI+LSLFVAVILDNLEL+ED+KKLKQLK  E +A+T++KLP+RLRIFEKFPNRPQM+K ++L SDF +PKIR+SFM+QF     ++ + +    +  ++     SS   +    I+               IR     +K  A+  ++    + RM+      QP     RS+LS QH IR ERR+LR+   + +  I++   L    ++       +  +    +IK++Q+K EQAE+KR  Q ++LRENHPYFDKPLF +GRE +FR  CR++V A++   K D  +   +   +++L    GLVTYLDWVMI VT  SCISM FE+P +RVM+   L++AEY+F + M+IE+ LK++A+G  FTP AV+RDFGGV+D FIY++ +IF+ +M +   + + SG Q+LM+LRCLRPLRIF LVP MR+VV EL  GF+EI +VS+LL+  M  FA +GV +F GKLA CNDP    ++DC G+F   +SV+K     L+     P F VPRVWANPRNFNFDN+GNAML LFEVLSL+GWVE+RDVI  RVG I+ IYIH+FVF+GC+IGLTLFVGVVIAN++ENKGTALLTVDQRRW DLK R+K+ QPLH+PPRP           DN+              R  +YD+TQH +FKR  A++VL   + L   W+ +D   +     LA+ +V +TFIF +E  +KI A+S  G+WQS+RN YD++VT L ++WV +H ++ + +   +     G   ++ RFFSI GKHVTLKML+ TV++SM+KS F+I+ MFLL+L YA AG++LFG+VKYGEN+ RHANF +  ++I +LFRIVTGEDWNKIMHDCMVQPPFCT  E  +W +DCGN+  +L+YFCSFY++I YIMLN+LVAII+ENFSLFYS +ED ++SYND+R+FQ  WN +D  R+ F
Sbjct:    3 KRKQSSRVEAQPV---TDFGPDESLSDNADILWINKPWVHSLLRICAIISVISVCMNTPMTFEHYPPLQYVTFTLDTLLMFLYTAEMIAKMHIRGIV----------------------KGDSSYVKDRWCVFDGFMVFCLWVSLVLQVFEIADIVDQMSP-------------WGML---RIPRPLIMIRAFRIYFRFELPRTRITNILKRSGEQIWSVSIFLLFFLLLYGILGVQMFGT-FTYHCVVNDTKPGNVTWNSLAIPDTHCSPELEEGYQCPPGFKCMDLEDLGLSRQELGYSGFNEIGTSIFTVYEAASQEGWVFLMYRAIDSFPRWRSYFYFITLIFFLAWLVKNVFIAVIIETFAEIRVQFQQMWGSRSSTTSTATTQMFHEDAAGGWQLVAVDVNKPQGRAPACLQKM-MRSSVFHMFILSMVTVDVIVAASNYYKGENFRRQYDEFYLAEVAFTVLFDLEALLKIWCLGFTGYISSSLHKFELLLVIGTTLHVYPDLYHSQFTYFQVLRVVRLIKISPALEDFVYKIFGPGKKLGSLVVFTASLLIVMSAISLQMFCFVE----ELDR------------------------------------------FTTFPR------------AFMSMFQILTQEGWVDVMDQTLNAVGHM-WAPVVAIYFILYHLFATLILLSLFVAVILDNLELDEDLKKLKQLKQSEANADTKEKLPLRLRIFEKFPNRPQMVKISKLPSDFTVPKIRESFMKQF-----IDRQQQDTCCLLRSLPTTSSSSCDHSKRSAIEDNKYIDQKLRKSVFSIRARNLLEKETAVTKILRACTRQRMLSGSFEGQPA--KERSILSVQHHIRQERRSLRH--GSNSQRISRGKSLETLTQDHSNTVRYRNAQREDSEIKMIQEKKEQAEMKRKVQEEELRENHPYFDKPLFIVGREHRFRNFCRVVVRARFNASKTDPVTGAVKNTKYHQLYDLLGLVTYLDWVMIIVTICSCISMMFESPFRRVMHAPTLQIAEYVFVIFMSIELNLKIMADGLFFTPTAVIRDFGGVMDIFIYLVSLIFLCWMPQ--NVPAESGAQLLMVLRCLRPLRIFKLVPQMRKVVRELFSGFKEIFLVSILLLTLMLVFASFGVQLFAGKLAKCNDPNIIRREDCNGIFRINVSVSKNLNLKLRPGEKKPGFWVPRVWANPRNFNFDNVGNAMLALFEVLSLKGWVEVRDVIIHRVGPIHGIYIHVFVFLGCMIGLTLFVGVVIANFNENKGTALLTVDQRRWEDLKSRLKIAQPLHLPPRP-----------DNDGF------------RAKMYDITQHPFFKRTIALLVLAQSVLLSVKWDVEDPVTVP----LATMSVVFTFIFVLEVTMKIIAMSPAGFWQSRRNRYDLLVTSLGVVWVVLHFALLNAYTYMM-----GACVIVFRFFSICGKHVTLKMLLLTVVVSMYKSFFIIVGMFLLLLCYAFAGVVLFGTVKYGENINRHANFSSAGKAITVLFRIVTGEDWNKIMHDCMVQPPFCTPDEFTYWATDCGNYAGALMYFCSFYVIIAYIMLNLLVAIIVENFSLFYSTEEDQLLSYNDLRHFQIIWNMVDDKRETF 1484

[Close]

BLAST of Voltage-dependent calcium channel vs. Ensembl Human
Match: CACNA1C (calcium voltage-gated channel subunit alpha1 C [Source:HGNC Symbol;Acc:HGNC:1390])

HSP 1 Score: 176.407 bits (446), Expect = 2.958e-43
Identity = 178/679 (26.22%), Postives = 307/679 (45.21%), Query Frame = 2

Query: 3074 VMIFVTTTSCISMAFETPTKRVM--NTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTKLKLSGDSPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEI-RDVIKARVGRINVIYIH---------LFVFIGCLIGLTLFVGVVIANYSENK----GTALLTVDQRRWLD--LKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILAS--FNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNH-----------NSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKYGE--NLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCM----VQPPFCTYRENFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFIKAFYVRFLLRLIPKDRVGF 4999
            +++F    S IS+A E P +     N I L  A+Y+F    T+E+ LK+ A G      +  R++  +LD  +  + +  +++ I+   I      +IL +LR LRPLR       ++ VV  +    R I  + ++  +  F FA  GV +F GKL  C+D +K  + +C G +     +T      D P  + PR W N + F+FDN+  AM+ LF V + EGW E+    I +       IY +         +++ I     + +FVG VI  + E          L  +QR+ ++  LK R         P R  + ++  Q +                     V+ +    YF+ +  +++L+N I L         YG      +A    N+ +T +F +E  LK+ A    GY+    N++D ++   S+I V +  +    H           NSR+ S  F  +  ++R   +  +   ++ L+ T + S     +V + + +L  +YA+ G+ +FG +   +   + R+ NF    +++ LLFR  TGE W  IM  CM      P          ++ CG+  A + YF SFY++  ++++N+ VA+IM+NF   Y   + +I+  + +  F++ W   D   KG IK   V  LLR I +  +GF
Sbjct:  905 LILFFILLSSISLAAEDPVQHTSFRNHI-LGNADYVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLV--VSVSLISFGIQSSAINV---VKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNY-----ITYKDGEVDHP-IIQPRSWENSK-FDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKAR---------PLRRYIPKNQHQYK---------------------VWYVVNSTYFEYLMFVLILLNTICLAM-----QHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSMNAEENSRI-SITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA-VFYFISFYMLCAFLIINLFVAVIMDNFD--YLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRI-QPPLGF 1530

HSP 2 Score: 128.257 bits (321), Expect = 1.301e-28
Identity = 167/668 (25.00%), Postives = 292/668 (43.71%), Query Frame = 2

Query: 3056 VTYLDW----VMIFVTT-TSCISMAFETP----TKRVMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICI--IFVAYMIRVDTIGSGSGK------QILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKL--------AICNDPTKTEKKDCV---GVFDRKISVTKLKLSGDSPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVGRI-NVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVD-------QRRWLDLKGRIK-LTQPLHIPPR----------------PKMRQDS--TQNRTDNNAINENS---FDNRVIKVRCWVYDLTQHIYFKRVSAIMVLIN-----CIFLYFPWNN----DDEYGMKR--SKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYD-MVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGS-VKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRENFWQSDCGNFQASL--IYFCSFYIMITYIMLNVLVAIIMENFS 4840
            ++ ++W    ++I +T   +C+++A   P         N+  L+  EY+F +  T+E  LKV+A G +F P A +R+   +LDF I ++ +    +    + D   +  GK      + L   R LRPLR+   VP ++ V+  +++    +L +++L++  +  +A+ G+ +F GK+         I + P + +   C    G   +  + T  K   D P   +          NFDN   AMLT+F+ +++EGW ++   +   VGR    IY    + IG    L L +GV+   +S+ +  A    D       Q+   DLKG +  +TQ   I P                 P    +S  T+N    +   EN      +R+ K +   Y    + + +R     V  N      IFL F  N      + Y      +++  + N     +F  E  LK+ +L    Y+ S  N +D  VV    L  + V   +       V+         LLR F I     +L  L+ ++L S+     +++ +FL +++++L G+ LFG    + E   R + F N  +S+  +F+I+TGEDWN +M+D ++                 +F   L  IYF   +I   YI+LNV +AI ++N +
Sbjct:  118 ISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNS-NLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGI---------TNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVF-LNTLTIASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGILETILVETKIMSPLGISVLR-----CVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIM------------AYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLA 757

HSP 3 Score: 67.781 bits (164), Expect = 2.710e-10
Identity = 110/530 (20.75%), Postives = 210/530 (39.62%), Query Frame = 2

Query:  662 LITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILH---------RSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSY---------FISMIFFLAWLVKNVFIAILTETFAEIRVQFQQMWSPKNQTDADSSKIFQTDGQRWKLVPVYESKP-HGLAPKLFQEI----VLKSTAFNVIIMLLVLANAIVAAGLHFNHDELTQTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHCMWYRTQ--------------------LTYFQVLRIFRLMK---ASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEP----KFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPN-------DWAQQLFSTFSGIYFILINLIFSFAFMSMF 2080
            LI+F  +   ++ ++  R L + R LR+         R K + H         R+   +  VT  L F   ++A +GVQ F   +  +    S+ +++ +     I        +K G+     ++     NS  D      F     +   ++  ++ EGW  ++YR++D   + KG  Y         FI  I  +A+ + N+F+  +  TF E             Q + +         QR  +    +++P     PK   +     V+ ST F  ++ +L+L N I  A  H+    L +        ++FT LF +E + K+     K Y+    + F+F++ +G+ +  +   T                     +T+F++ R+ RL+K       +    +    S + L  + L    L  I + + +Q+F  I + +     + + F  FP+A L +F   T E W ++M   M   K  P        +      S+F+  YFI   ++ +F  +++F
Sbjct:  981 LISFGIQSSAINVVKILRVLRVLRPLRAI-------NRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQF---MFACIGVQLFKGKL--YTCSDSSKQTEAECKGNYI-------TYKDGEVDHPIIQPRSWENSKFD------FDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQE-------------QGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKI-AMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLF 1471

HSP 4 Score: 67.0106 bits (162), Expect = 4.527e-10
Identity = 69/278 (24.82%), Postives = 117/278 (42.09%), Query Frame = 2

Query:  524 PHAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGL--LSTLRSPRPLILTR-------VLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQ-WKGVSYFISMIFFLAWLVKNVFIAILTETF------AEIRVQFQQMWSPKNQTDAD 1309
            P+AYLR+ W   D I+V+    S          +++  T  D    L      + +  L   R  RPL L         VL S +K  +P      +LH        + + +LF + +YAI+G++ F   ++  C  Q    +D+   D   P   C  +   G  C     C    +  +   G   F  F F+  TV+Q  + EGW  ++Y   D + + W  + YF+++I   ++ V N+ + +L+  F      A+ R  FQ++   K Q + D
Sbjct:  187 PNAYLRNGWNLLDFIIVVVGLFS---------AILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVP------LLH--------IALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGI-ADVPAEDDPSP---CALETGHGRQCQNGTVCKPGWDGPKH--GITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDWPWI-YFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLRE-KQQLEED 433

HSP 5 Score: 52.7582 bits (125), Expect = 9.145e-6
Identity = 59/241 (24.48%), Postives = 111/241 (46.06%), Query Frame = 2

Query: 1409 VLKSTAFNVIIMLLVLANAIVAAGLHFNHDE-LTQTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFE-FILCLG--------TTVHCMWYRTQLTYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFC---SIQIYEPKFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPNDWAQQLFSTFSG----IYFILINLIFSFAFMSMF 2080
             +KS  F  +++ LV  N +  A  H+N    LT+      A      LF  E + K++ LG ++Y+    ++F+ F++C G        T +      + L   ++LRIF++ +    L +    +  S + +  L+L     +II S + +QLF    +    + +   F NFP++ L +F ++T E W  VM   ++ A   P         +F G    IYFI++ +  ++  +++F
Sbjct:  520 AVKSNVFYWLVIFLVFLNTLTIASEHYNQPNWLTEVQD--TANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIM-AYGGP---------SFPGMLVCIYFIILFICGNYILLNVF 748

[Close]

Query: 3074 VMIFVTTTSCISMAFETPTKRVM--NTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTKLKLSGDSPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEI-RDVIKARVGRINVIYIH---------LFVFIGCLIGLTLFVGVVIANYSENK----GTALLTVDQRRWLD--LKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILAS--FNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNH-----------NSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKYGE--NLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCM----VQPPFCTYRENFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFIKAFYVRFLLRLIPKDRVGF 4999
            +++F    S IS+A E P +     N I L  A+Y+F    T+E+ LK+ A G      +  R++  +LD  +  + +  +++ I+   I      +IL +LR LRPLR       ++ VV  +    R I  + ++  +  F FA  GV +F GKL  C+D +K  + +C G +     +T      D P  + PR W N + F+FDN+  AM+ LF V + EGW E+    I +       IY +         +++ I     + +FVG VI  + E          L  +QR+ ++  LK R         P R  + ++  Q +                     V+ +    YF+ +  +++L+N I L         YG      +A    N+ +T +F +E  LK+ A    GY+    N++D ++   S+I V +  +    H           NSR+ S  F  +  ++R   +  +   ++ L+ T + S     +V + + +L  +YA+ G+ +FG +   +   + R+ NF    +++ LLFR  TGE W  IM  CM      P          ++ CG+  A + YF SFY++  ++++N+ VA+IM+NF   Y   + +I+  + +  F++ W   D   KG IK   V  LLR I +  +GF
Sbjct:  905 LILFFILLSSISLAAEDPVQHTSFRNHI-LGNADYVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLV--VSVSLISFGIQSSAINV---VKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNY-----ITYKDGEVDHP-IIQPRSWENSK-FDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKAR---------PLRRYIPKNQHQYK---------------------VWYVVNSTYFEYLMFVLILLNTICLAM-----QHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSMNAEENSRI-SITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA-VFYFISFYMLCAFLIINLFVAVIMDNFD--YLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRI-QPPLGF 1530

HSP 2 Score: 128.257 bits (321), Expect = 1.301e-28
Identity = 167/668 (25.00%), Postives = 292/668 (43.71%), Query Frame = 2

Query: 3056 VTYLDW----VMIFVTT-TSCISMAFETP----TKRVMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICI--IFVAYMIRVDTIGSGSGK------QILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKL--------AICNDPTKTEKKDCV---GVFDRKISVTKLKLSGDSPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVGRI-NVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVD-------QRRWLDLKGRIK-LTQPLHIPPR----------------PKMRQDS--TQNRTDNNAINENS---FDNRVIKVRCWVYDLTQHIYFKRVSAIMVLIN-----CIFLYFPWNN----DDEYGMKR--SKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYD-MVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGS-VKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRENFWQSDCGNFQASL--IYFCSFYIMITYIMLNVLVAIIMENFS 4840
            ++ ++W    ++I +T   +C+++A   P         N+  L+  EY+F +  T+E  LKV+A G +F P A +R+   +LDF I ++ +    +    + D   +  GK      + L   R LRPLR+   VP ++ V+  +++    +L +++L++  +  +A+ G+ +F GK+         I + P + +   C    G   +  + T  K   D P   +          NFDN   AMLT+F+ +++EGW ++   +   VGR    IY    + IG    L L +GV+   +S+ +  A    D       Q+   DLKG +  +TQ   I P                 P    +S  T+N    +   EN      +R+ K +   Y    + + +R     V  N      IFL F  N      + Y      +++  + N     +F  E  LK+ +L    Y+ S  N +D  VV    L  + V   +       V+         LLR F I     +L  L+ ++L S+     +++ +FL +++++L G+ LFG    + E   R + F N  +S+  +F+I+TGEDWN +M+D ++                 +F   L  IYF   +I   YI+LNV +AI ++N +
Sbjct:  118 ISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNS-NLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGI---------TNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVF-LNTLTIASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGILETILVETKIMSPLGISVLR-----CVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIM------------AYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLA 757

HSP 3 Score: 67.781 bits (164), Expect = 2.710e-10
Identity = 110/530 (20.75%), Postives = 210/530 (39.62%), Query Frame = 2

Query:  662 LITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILH---------RSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSY---------FISMIFFLAWLVKNVFIAILTETFAEIRVQFQQMWSPKNQTDADSSKIFQTDGQRWKLVPVYESKP-HGLAPKLFQEI----VLKSTAFNVIIMLLVLANAIVAAGLHFNHDELTQTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHCMWYRTQ--------------------LTYFQVLRIFRLMK---ASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEP----KFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPN-------DWAQQLFSTFSGIYFILINLIFSFAFMSMF 2080
            LI+F  +   ++ ++  R L + R LR+         R K + H         R+   +  VT  L F   ++A +GVQ F   +  +    S+ +++ +     I        +K G+     ++     NS  D      F     +   ++  ++ EGW  ++YR++D   + KG  Y         FI  I  +A+ + N+F+  +  TF E             Q + +         QR  +    +++P     PK   +     V+ ST F  ++ +L+L N I  A  H+    L +        ++FT LF +E + K+     K Y+    + F+F++ +G+ +  +   T                     +T+F++ R+ RL+K       +    +    S + L  + L    L  I + + +Q+F  I + +     + + F  FP+A L +F   T E W ++M   M   K  P        +      S+F+  YFI   ++ +F  +++F
Sbjct:  981 LISFGIQSSAINVVKILRVLRVLRPLRAI-------NRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQF---MFACIGVQLFKGKL--YTCSDSSKQTEAECKGNYI-------TYKDGEVDHPIIQPRSWENSKFD------FDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQE-------------QGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKI-AMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLF 1471

HSP 4 Score: 67.0106 bits (162), Expect = 4.527e-10
Identity = 69/278 (24.82%), Postives = 117/278 (42.09%), Query Frame = 2

Query:  524 PHAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGL--LSTLRSPRPLILTR-------VLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQ-WKGVSYFISMIFFLAWLVKNVFIAILTETF------AEIRVQFQQMWSPKNQTDAD 1309
            P+AYLR+ W   D I+V+    S          +++  T  D    L      + +  L   R  RPL L         VL S +K  +P      +LH        + + +LF + +YAI+G++ F   ++  C  Q    +D+   D   P   C  +   G  C     C    +  +   G   F  F F+  TV+Q  + EGW  ++Y   D + + W  + YF+++I   ++ V N+ + +L+  F      A+ R  FQ++   K Q + D
Sbjct:  187 PNAYLRNGWNLLDFIIVVVGLFS---------AILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVP------LLH--------IALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGI-ADVPAEDDPSP---CALETGHGRQCQNGTVCKPGWDGPKH--GITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDWPWI-YFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLRE-KQQLEED 433

HSP 5 Score: 52.7582 bits (125), Expect = 9.145e-6
Identity = 59/241 (24.48%), Postives = 111/241 (46.06%), Query Frame = 2

Query: 1409 VLKSTAFNVIIMLLVLANAIVAAGLHFNHDE-LTQTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFE-FILCLG--------TTVHCMWYRTQLTYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFC---SIQIYEPKFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPNDWAQQLFSTFSG----IYFILINLIFSFAFMSMF 2080
             +KS  F  +++ LV  N +  A  H+N    LT+      A      LF  E + K++ LG ++Y+    ++F+ F++C G        T +      + L   ++LRIF++ +    L +    +  S + +  L+L     +II S + +QLF    +    + +   F NFP++ L +F ++T E W  VM   ++ A   P         +F G    IYFI++ +  ++  +++F
Sbjct:  520 AVKSNVFYWLVIFLVFLNTLTIASEHYNQPNWLTEVQD--TANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIM-AYGGP---------SFPGMLVCIYFIILFICGNYILLNVF 748

[Close]

BLAST of Voltage-dependent calcium channel vs. Ensembl Human
Match: CACNA1C (calcium voltage-gated channel subunit alpha1 C [Source:HGNC Symbol;Acc:HGNC:1390])

HSP 1 Score: 174.096 bits (440), Expect = 1.507e-42
Identity = 178/679 (26.22%), Postives = 306/679 (45.07%), Query Frame = 2

Query: 3074 VMIFVTTTSCISMAFETPTKRVM--NTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTKLKLSGDSPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEI-RDVIKARVGRINVIYIH---------LFVFIGCLIGLTLFVGVVIANYSENK----GTALLTVDQRRWLD--LKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILAS--FNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNH-----------NSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKYGE--NLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCM----VQPPFCTYRENFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFIKAFYVRFLLRLIPKDRVGF 4999
            +++F    S IS+A E P +     N I L   + +F    TIE+ALK+ A G      +  R++  +LD  +  + +  +++ I+   I      +IL +LR LRPLR       ++ VV  +    R I  + ++  +  F FA  GV +F GKL  C+D +K  + +C G +     +T      D P  + PR W N + F+FDN+  AM+ LF V + EGW E+    I +       IY +         +++ I     + +FVG VI  + E          L  +QR+ ++  LK R         P R  + ++  Q +                     V+ +    YF+ +  +++L+N I L         YG      +A    N+ +T +F +E  LK+ A    GY+    N++D ++   S+I V +  +    H           NSR+ S  F  +  ++R   +  +   ++ L+ T + S     +V + + +L  +YA+ G+ +FG +   +   + R+ NF    +++ LLFR  TGE W  IM  CM      P          ++ CG+  A + YF SFY++  ++++N+ VA+IM+NF   Y   + +I+  + +  F++ W   D   KG IK   V  LLR I +  +GF
Sbjct:  905 LILFFILLSSISLAAEDPVQHTSFRNHI-LFYFDIVFTTIFTIEIALKMTAYGAFLHKGSFCRNYFNILDLLV--VSVSLISFGIQSSAINV---VKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNY-----ITYKDGEVDHP-IIQPRSWENSK-FDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKAR---------PLRRYIPKNQHQYK---------------------VWYVVNSTYFEYLMFVLILLNTICLAM-----QHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSMNAEENSRI-SITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA-VFYFISFYMLCAFLIINLFVAVIMDNFD--YLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRI-QPPLGF 1530

HSP 2 Score: 128.642 bits (322), Expect = 9.370e-29
Identity = 167/668 (25.00%), Postives = 292/668 (43.71%), Query Frame = 2

Query: 3056 VTYLDW----VMIFVTT-TSCISMAFETP----TKRVMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICI--IFVAYMIRVDTIGSGSGK------QILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKL--------AICNDPTKTEKKDCV---GVFDRKISVTKLKLSGDSPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVGRI-NVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVD-------QRRWLDLKGRIK-LTQPLHIPPR----------------PKMRQDS--TQNRTDNNAINENS---FDNRVIKVRCWVYDLTQHIYFKRVSAIMVLIN-----CIFLYFPWNN----DDEYGMKR--SKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYD-MVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGS-VKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRENFWQSDCGNFQASL--IYFCSFYIMITYIMLNVLVAIIMENFS 4840
            ++ ++W    ++I +T   +C+++A   P         N+  L+  EY+F +  T+E  LKV+A G +F P A +R+   +LDF I ++ +    +    + D   +  GK      + L   R LRPLR+   VP ++ V+  +++    +L +++L++  +  +A+ G+ +F GK+         I + P + +   C    G   +  + T  K   D P   +          NFDN   AMLT+F+ +++EGW ++   +   VGR    IY    + IG    L L +GV+   +S+ +  A    D       Q+   DLKG +  +TQ   I P                 P    +S  T+N    +   EN      +R+ K +   Y    + + +R     V  N      IFL F  N      + Y      +++  + N     +F  E  LK+ +L    Y+ S  N +D  VV    L  + V   +       V+         LLR F I     +L  L+ ++L S+     +++ +FL +++++L G+ LFG    + E   R + F N  +S+  +F+I+TGEDWN +M+D ++                 +F   L  IYF   +I   YI+LNV +AI ++N +
Sbjct:  118 ISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNS-NLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGI---------TNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVF-LNTLTIASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGILETILVETKIMSPLGISVLR-----CVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIM------------AYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLA 757

HSP 3 Score: 68.5514 bits (166), Expect = 1.707e-10
Identity = 130/628 (20.70%), Postives = 235/628 (37.42%), Query Frame = 2

Query:  368 YVTYLLDIVVALLFTAEMFTKMKIKGIIRPSPYVIVRHLFFVKVSNNIENKRPHAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILH---------RSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSY---------FISMIFFLAWLVKNVFIAILTETFAEIRVQFQQMWSPKNQTDADSSKIFQTDGQRWKLVPVYESKP-HGLAPKLFQEI----VLKSTAFNVIIMLLVLANAIVAAGLHFNHDELTQTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHCMWYRTQ--------------------LTYFQVLRIFRLMK---ASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEP----KFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPN-------DWAQQLFSTFSGIYFILINLIFSFAFMSMF 2080
            ++ +  DIV   +FT E+  KM   G             F  K S          + R+++   D ++V    IS  IQ+   + V+K                   +L  LR  RPL   R +           R K + H         R+   +  VT  L F   ++A +GVQ F   +          E++ K   +          +K G+     ++     NS  D      F     +   ++  ++ EGW  ++YR++D   + KG  Y         FI  I  +A+ + N+F+  +  TF E             Q + +         QR  +    +++P     PK   +     V+ ST F  ++ +L+L N I  A  H+    L +        ++FT LF +E + K+     K Y+    + F+F++ +G+ +  +   T                     +T+F++ R+ RL+K       +    +    S + L  + L    L  I + + +Q+F  I + +     + + F  FP+A L +F   T E W ++M   M   K  P        +      S+F+  YFI   ++ +F  +++F
Sbjct:  931 HILFYFDIVFTTIFTIEIALKMTAYGA------------FLHKGS----------FCRNYFNILDLLVVSVSLISFGIQS-SAINVVK-------------------ILRVLRVLRPL---RAI----------NRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQF---MFACIGVQLFKGKLYTCSDSSKQTEAECKGNYIT---------YKDGEVDHPIIQPRSWENSKFD------FDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQE-------------QGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKI-AMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLF 1471

HSP 4 Score: 67.3958 bits (163), Expect = 3.957e-10
Identity = 69/278 (24.82%), Postives = 117/278 (42.09%), Query Frame = 2

Query:  524 PHAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGL--LSTLRSPRPLILTR-------VLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQ-WKGVSYFISMIFFLAWLVKNVFIAILTETF------AEIRVQFQQMWSPKNQTDAD 1309
            P+AYLR+ W   D I+V+    S          +++  T  D    L      + +  L   R  RPL L         VL S +K  +P      +LH        + + +LF + +YAI+G++ F   ++  C  Q    +D+   D   P   C  +   G  C     C    +  +   G   F  F F+  TV+Q  + EGW  ++Y   D + + W  + YF+++I   ++ V N+ + +L+  F      A+ R  FQ++   K Q + D
Sbjct:  187 PNAYLRNGWNLLDFIIVVVGLFS---------AILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVP------LLH--------IALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGI-ADVPAEDDPSP---CALETGHGRQCQNGTVCKPGWDGPKH--GITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDWPWI-YFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLRE-KQQLEED 433

HSP 5 Score: 53.1434 bits (126), Expect = 7.927e-6
Identity = 59/241 (24.48%), Postives = 111/241 (46.06%), Query Frame = 2

Query: 1409 VLKSTAFNVIIMLLVLANAIVAAGLHFNHDE-LTQTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFE-FILCLG--------TTVHCMWYRTQLTYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFC---SIQIYEPKFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPNDWAQQLFSTFSG----IYFILINLIFSFAFMSMF 2080
             +KS  F  +++ LV  N +  A  H+N    LT+      A      LF  E + K++ LG ++Y+    ++F+ F++C G        T +      + L   ++LRIF++ +    L +    +  S + +  L+L     +II S + +QLF    +    + +   F NFP++ L +F ++T E W  VM   ++ A   P         +F G    IYFI++ +  ++  +++F
Sbjct:  520 AVKSNVFYWLVIFLVFLNTLTIASEHYNQPNWLTEVQD--TANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIM-AYGGP---------SFPGMLVCIYFIILFICGNYILLNVF 748

[Close]

BLAST of Voltage-dependent calcium channel vs. Ensembl Celegans
Match: nca-2 (Four domain-type voltage-gated ion channel alpha-1 subunit; Novel Channel type/putative Nematode CAlcium channel [Source:UniProtKB/TrEMBL;Acc:G5EG32])

HSP 1 Score: 1298.88 bits (3360), Expect = 0.000e+0
Identity = 746/1688 (44.19%), Postives = 1035/1688 (61.32%), Query Frame = 2

Query:  329 NTPETFKEYKWLFYVTYLLDIVVALLFTAEMFTKMKIKGIIRPSPYVIVRHLFFVKVSNNIENKRPHAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWLVKNVFIAILTETFAEIRVQFQQMWSPKNQT-DADSSKIFQTDGQRWKLVPVYESKPHGLAPKLFQEIVLKSTAFNVIIMLLVLANAIVAAGLHFNHDELTQTNG--FYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHCMW--YRTQL-TYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEPKFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPNDWAQQLFSTFSGIYFILINLIFSFAFMSMFQILTQKGWVIVMHDTMDMAKHRGLNALVAIYFVFYHLFVTLIVLSLFVAVILDNLELEEDIKKLKQLKLREMSAETQQKLPMRLRIFEKFPNRPQMIKPARLLSDFLIPKIRDSFMRQFAQLPTLEEENESDEM---IAAAVSGVGVSSLPRALSIEIKRQIRGLKGNDKLNAIIYLINESNKTRMI----EQPIIYPTRSLLSTQH----QIRTERRNLRNRMAATTMS--INQKPRLNGEIRNMDFETNRKTEEANHFDIKILQQKAEQAEIKRNQQVDDLRENHPYFDKPLFTIGRESQFRQLCRMLVEAQYKPDINSENPEKQT--FYKLQKFFGLVTYLDWVMIFVTTTSCISMAFETP-----TKRVMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTKLKLSGDS-----PSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVGRINVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVDQRRWLDLKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKI-LASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQ-------DNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRE--NFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFIKAFYVRFLLRLIPKDRVGFDFTKKKDQQLFKEMCYEVELLRGGKDKEVSFHDVLTMLAYRSVDISKTXXXXXXXXXXXXXXXXXXXXXRQTIATWIERCIFRNRQKHGD 5269
            +TPET K +  L Y+    D++V L+F  E    +   G+                     +N+  ++YLR  W  F+  ++I   +S  I  +EL     C     +   +   W     L  LRS RP I  R +RS ++F+LP+ R+K I+ RS+ Q+ NVT+F +FF+  YAI+GVQ FG  +N+HCV+   + +++ I DLAIPD+ C+ K   G  CP +M C+++    ++EG Y  F  F  S FTVY AASQEGWV+++Y  +D LP +    YF+++IFFLAWLVKNVFIA++TETFAEIRVQF +MW  +  T D   ++  + D   WKLV V +         LF   ++ STAF  ++ LL+LANAI  A   F HDE  Q     +YY E+ FTILFN E + KI+  GWK+Y  R  HKF+ ILC+G++++ +W  Y T + TYFQV RI RL+KASPMLEDF +KIFG GKKLG L++FT  LLI+TS++S                        LQ+F  V +               K  N                     F+ AFMSMFQI+TQ+GW  V+ + +     + +   VAIYFV YHL VTL VLSLFVAVILDNLE++E++KK+KQLK RE     +  LPMRLRIF +FP  P M+   ++ S+F +PKIRDSF RQFA       ++   E+   + + +SG G S   R     I   IR +        +  ++ ESN+ R +     Q +   TRS  S++H     + T  R+ R R  A+     + +  + NG++R  D  T RK E+    D K LQ K   AEI RN+  +++RENHP FD+PLF +GRES  R++C+++  +++  D N     K +  + +   F  ++TY+DW M+ VTT SC SM +E+P        + N   L++AEYIF + M+ E+ +K +ANG  FTPKA+V D G +L  FIYI  ++F+ +M   + I   S  Q+LM+ R +RPLR++ L+PH+RRVV EL RGFREIL+V++LLVV MF FA +GV + GGKLA CNDP  T +++C G++D K+ VT++++ G +     PS +VPRVW NPRNFNFD+IGNAML LFE LS +GW  +RDV+  R G   V++IH++VFIGC+IGLTLFVGVV+ANY+EN+GTALLTVDQRRW DLK R+K+ QPLH+PP+P                          K+RC++YDLT   +FK++ A++V++N   L  PWN  +E   K   + L   +     +F +EC LK+ A +  G+WQS+RN  D ++T L + W+  H   Q            + ++  +G++ V+LRFF+IAG+  TLKMLM TV+MSM +S F+I AMFLL+L YA AG++LFG VKYG+ +G+H NF N   ++ +LFR VTGEDWN IMHDCM  PPFC +    ++WQ+DCGN+  +++YFCSFY++ITYI+LN+LVAIIMENFSLFYS++EDA++SY DIRNFQ  WN +D+ +K  I    V+FLLRL+ K R+  +   + D  LFK MC+E+E L  G D  VSFHDVL ML+YRSVDI K+LQLEELL REELEY IEEEVA+ TI  W+E C+   + K  +
Sbjct:   70 HTPETIKMWPPLNYIILANDVIVTLIFIGEAAVTINQNGLF--------------------DNQ--NSYLRDRWYQFEFFLLINHILSCVIHIYEL-----CSIWFPALNFVYYPW-----LGALRSARPFIFLRFIRSIVRFKLPKNRIKLIIKRSSQQIQNVTIFFMFFVFSYAIMGVQLFGR-LNYHCVVNGTDPNNVTIADLAIPDTMCSQKGAGGYECPGNMVCMRLQLKPQEEGFYGQFSDFASSLFTVYLAASQEGWVYVLYDCLDSLPSFLAFFYFVTLIFFLAWLVKNVFIAVITETFAEIRVQFSEMWQTREATTDHVYTQKLEKDEDGWKLVEVDKYNRAHSNNSLFLHTIVTSTAFQTVMQLLILANAIFHATFVFYHDESDQIRKIWYYYVEVGFTILFNTEVIIKIYAFGWKAYIARGQHKFDCILCVGSSLNAIWVLYETNIFTYFQVFRIARLIKASPMLEDFVYKIFGPGKKLGGLVIFTGILLIVTSAIS------------------------LQLFCYVPK-------------LNKFTN---------------------FAVAFMSMFQIITQEGWTDVVIEILRACNEQAV-PFVAIYFVAYHLLVTLFVLSLFVAVILDNLEMDEELKKVKQLKAREQDT-IKTTLPMRLRIFNRFPTAPTMVTMKKVSSEFPLPKIRDSFTRQFADEFVETSDDTIQEIGFKVRSMLSGRGPSKETR-----ITTTIRHVGQLSNKTILTSMLTESNRNRALFSESNQHLASLTRSNTSSKHGKSGALSTNSRS-RTRGLASLKGKHMVEGFKENGDLRPED--TARKVEKHGEIDFKALQMKRAHAEITRNRIEEEMRENHPMFDRPLFLVGRESSLRRMCQLIAHSRHSYDQNDGQHRKHSNKYKQFHDFLAIMTYMDWTMVLVTTLSCCSMLWESPWPTTGENLIFNNFYLQIAEYIFVLVMSFELIVKCIANGLFFTPKALVTDVGDILTIFIYITSLMFLIWM--PNHIEINSWAQLLMVCRAMRPLRVYALIPHIRRVVVELCRGFREILLVTILLVVLMFIFASFGVQLVGGKLASCNDPMITSRENCTGLYDVKLFVTRMEVYGKNDNLMHPSIIVPRVWTNPRNFNFDHIGNAMLALFETLSYKGWNVVRDVLYLRHGAWAVLFIHIYVFIGCMIGLTLFVGVVVANYTENRGTALLTVDQRRWHDLKARLKMAQPLHVPPKPP----------------------ESAKLRCYLYDLTTSRWFKQLFAVLVVVNSFTLVIPWNVSEEQDRKTFLLCLTVISAICNILFTLECLLKMIAFTLSGFWQSRRNRIDFIITILGINWIVFHFLFQLPAYFAGGITEWKRLTYTYGYLVVILRFFTIAGRKSTLKMLMLTVVMSMVRSSFIIAAMFLLVLFYANAGVVLFGMVKYGQAVGKHVNFRNGREALVVLFRSVTGEDWNDIMHDCMRAPPFCNWHPGLSYWQTDCGNYVGAIVYFCSFYLIITYIVLNLLVAIIMENFSLFYSSEEDALLSYADIRNFQLVWNMVDIEQKRSIPVRRVKFLLRLL-KGRL--EVNDESDGLLFKHMCHEMERLHNGDD--VSFHDVLNMLSYRSVDIRKSLQLEELLQREELEYIIEEEVAKHTIRAWLENCLKNIKAKQNN 1627

[Close]

BLAST of Voltage-dependent calcium channel vs. Ensembl Celegans
Match: nca-2 (Four domain-type voltage-gated ion channel alpha-1 subunit; Novel Channel type/putative Nematode CAlcium channel [Source:UniProtKB/TrEMBL;Acc:G5EG32])

HSP 1 Score: 1293.49 bits (3346), Expect = 0.000e+0
Identity = 738/1688 (43.72%), Postives = 1036/1688 (61.37%), Query Frame = 2

Query:  329 NTPETFKEYKWLFYVTYLLDIVVALLFTAEMFTKMKIKGIIRPSPYVIVRHLFFVKVSNNIENKRPHAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWLVKNVFIAILTETFAEIRVQFQQMWSPKNQ-TDADSSKIFQTDGQRWKLVPVYESKPHGLAPKLFQEIVLKSTAFNVIIMLLVLANAIVAAGLHFNHDELTQTNG--FYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHCMW--YRTQL-TYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEPKFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPNDWAQQLFSTFSGIYFILINLIFSFAFMSMFQILTQKGWVIVMHDTMDMAKHRGLNALVAIYFVFYHLFVTLIVLSLFVAVILDNLELEEDIKKLKQLKLREMSAETQQKLPMRLRIFEKFPNRPQMIKPARLLSDFLIPKIRDSFMRQFAQLPTLEEENESDEM---IAAAVSGVGVSSLPRALSIEIKRQIRGLKGNDKLNAIIYLINESNKTRMI----EQPIIYPTRSLLSTQH----QIRTERRNLRNRMAATTMS--INQKPRLNGEIRNMDFETNRKTEEANHFDIKILQQKAEQAEIKRNQQVDDLRENHPYFDKPLFTIGRESQFRQLCRMLVEAQYKPDINSENPEKQT--FYKLQKFFGLVTYLDWVMIFVTTTSCISMAFETP-----TKRVMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTKLKLSGDS-----PSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVGRINVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVDQRRWLDLKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKI-LASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQ-------DNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRE--NFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFIKAFYVRFLLRLIPKDRVGFDFTKKKDQQLFKEMCYEVELLRGGKDKEVSFHDVLTMLAYRSVDISKTXXXXXXXXXXXXXXXXXXXXXRQTIATWIERCIFRNRQKHGD 5269
            +TPET K +  L Y+    D++V L+F  E    +   G+                     +N+  ++YLR  W  F+  ++I   +S  I  +EL     C     +   +   W     L  LRS RP I  R +RS ++F+LP+ R+K I+ RS+ Q+ NVT+F +FF+  YAI+GVQ FG  +N+HCV+   + +++ I DLAIPD+ C+ K   G  CP +M C+++    ++EG Y  F  F  S FTVY AASQEGWV+++Y  +D LP +    YF+++IFFLAWLVKNVFIA++TETFAEIRVQF +MW  +   TD   ++  + D   WKLV V +         LF   ++ STAF  ++ LL+LANAI  A   F HDE  Q     +YY E+ FTILFN E + KI+  GWK+Y  R  HKF+ ILC+G++++ +W  Y T + TYFQV RI RL+KASPMLEDF +KIFG GKKLG L++FT  LLI+TS++SLQLFC    Y PK ++F+NF  AF+ +F ++T+EGW +V    +I+  +  N+ A      F  IYF+  +L+ +   +S+                                               FVAVILDNLE++E++KK+KQLK RE     +  LPMRLRIF +FP  P M+   ++ S+F +PKIRDSF RQFA       ++   E+   + + +SG G S   R     I   IR +        +  ++ ESN+ R +     Q +   TRS  S++H     + T  R+ R R  A+     + +  + NG++R  D  T RK E+    D K LQ K   AEI RN+  +++RENHP FD+PLF +GRES  R++C+++  +++  D N     K +  + +   F  ++TY+DW M+ VTT SC SM +E+P        + N   L++AEYIF + M+ E+ +K +ANG  FTPKA+V D G +L  FIYI  ++F+ +M   + I   S  Q+LM+ R +RPLR++ L+PH+RRVV EL RGFREIL+V++LLVV MF FA +GV + GGKLA CNDP  T +++C G++D K+ VT++++ G +     PS +VPRVW NPRNFNFD+IGNAML LFE LS +GW  +RDV+  R G   V++IH++VFIGC+IGLTLFVGVV+ANY+EN+GTALLTVDQRRW DLK R+K+ QPLH+PP+P                          K+RC++YDLT   +FK++ A++V++N   L  PWN  +E   K   + L   +     +F +EC LK+ A +  G+WQS+RN  D ++T L + W+  H   Q            + ++  +G++ V+LRFF+IAG+  TLKMLM TV+MSM +S F+I AMFLL+L YA AG++LFG VKYG+ +G+H NF N   ++ +LFR VTGEDWN IMHDCM  PPFC +    ++WQ+DCGN+  +++YFCSFY++ITYI+LN+LVAIIMENFSLFYS++EDA++SY DIRNFQ  WN +D+ +K  I    V+FLLRL+ K R+  +   + D  LFK MC+E+E L  G D  VSFHDVL ML+YRSVDI K+LQLEELL REELEY IEEEVA+ TI  W+E C+   + K  +
Sbjct:   92 HTPETIKMWPPLNYIILANDVIVTLIFIGEAAVTINQNGLF--------------------DNQ--NSYLRDRWYQFEFFLLINHILSCVIHIYEL-----CSIWFPALNFVYYPW-----LGALRSARPFIFLRFIRSIVRFKLPKNRIKLIIKRSSQQIQNVTIFFMFFVFSYAIMGVQLFGR-LNYHCVVNGTDPNNVTIADLAIPDTMCSQKGAGGYECPGNMVCMRLQLKPQEEGFYGQFSDFASSLFTVYLAASQEGWVYVLYDCLDSLPSFLAFFYFVTLIFFLAWLVKNVFIAVITETFAEIRVQFSEMWQTREATTDHVYTQKLEKDEDGWKLVEVDKYNRAHSNNSLFLHTIVTSTAFQTVMQLLILANAIFHATFVFYHDESDQIRKIWYYYVEVGFTILFNTEVIIKIYAFGWKAYIARGQHKFDCILCVGSSLNAIWVLYETNIFTYFQVFRIARLIKASPMLEDFVYKIFGPGKKLGGLVIFTGILLIVTSAISLQLFC----YVPKLNKFTNFAVAFMSMFQIITQEGWTDV----VIEILRACNEQA----VPFVAIYFVAYHLLVTLFVLSL-----------------------------------------------FVAVILDNLEMDEELKKVKQLKAREQDT-IKTTLPMRLRIFNRFPTAPTMVTMKKVSSEFPLPKIRDSFTRQFADEFVETSDDTIQEIGFKVRSMLSGRGPSKETR-----ITTTIRHVGQLSNKTILTSMLTESNRNRALFSESNQHLASLTRSNTSSKHGKSGALSTNSRS-RTRGLASLKGKHMVEGFKENGDLRPED--TARKVEKHGEIDFKALQMKRAHAEITRNRIEEEMRENHPMFDRPLFLVGRESSLRRMCQLIAHSRHSYDQNDGQHRKHSNKYKQFHDFLAIMTYMDWTMVLVTTLSCCSMLWESPWPTTGENLIFNNFYLQIAEYIFVLVMSFELIVKCIANGLFFTPKALVTDVGDILTIFIYITSLMFLIWM--PNHIEINSWAQLLMVCRAMRPLRVYALIPHIRRVVVELCRGFREILLVTILLVVLMFIFASFGVQLVGGKLASCNDPMITSRENCTGLYDVKLFVTRMEVYGKNDNLMHPSIIVPRVWTNPRNFNFDHIGNAMLALFETLSYKGWNVVRDVLYLRHGAWAVLFIHIYVFIGCMIGLTLFVGVVVANYTENRGTALLTVDQRRWHDLKARLKMAQPLHVPPKPP----------------------ESAKLRCYLYDLTTSRWFKQLFAVLVVVNSFTLVIPWNVSEEQDRKTFLLCLTVISAICNILFTLECLLKMIAFTLSGFWQSRRNRIDFIITILGINWIVFHFLFQLPAYFAGGITEWKRLTYTYGYLVVILRFFTIAGRKSTLKMLMLTVVMSMVRSSFIIAAMFLLVLFYANAGVVLFGMVKYGQAVGKHVNFRNGREALVVLFRSVTGEDWNDIMHDCMRAPPFCNWHPGLSYWQTDCGNYVGAIVYFCSFYLIITYIVLNLLVAIIMENFSLFYSSEEDALLSYADIRNFQLVWNMVDIEQKRSIPVRRVKFLLRLL-KGRL--EVNDESDGLLFKHMCHEMERLHNGDD--VSFHDVLNMLSYRSVDIRKSLQLEELLQREELEYIIEEEVAKHTIRAWLENCLKNIKAKQNN 1649

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BLAST of Voltage-dependent calcium channel vs. Ensembl Celegans
Match: unc-77 (pep chromosome:WBcel235:IV:6157312:6173040:-1 gene:WBGene00006809.1 transcript:C11D2.6d.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:unc-77)

HSP 1 Score: 1238.79 bits (3204), Expect = 0.000e+0
Identity = 739/1718 (43.02%), Postives = 1031/1718 (60.01%), Query Frame = 2

Query:  284 AFKIXXXXXXXXXXXNTPETFKEYKWLFYVTYLLDIVVALLFTAEMFTKMKIKGIIRPSPYVIVRHLFFVKVSNNIENKRPHAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWLVKNVFIAILTETFAEIRVQFQQMWSPKNQT-DADSSKIFQTDGQRWKLVPV-YESKPHGLAPKLFQEIVLKSTAFNVIIMLLVLANAIVAAGLHFNHDELTQTN--GFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHCM---WYRTQLTYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEPKFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPNDWAQQLFSTFSGIYFILINLIFSFAFMSMFQILTQKGWVIVMHDTMDMAKHRGLNALVAIYFVFYHLFVTLIVLSLFVAVILDNLELEEDIKKLKQLKLREMSAETQQKLPMRLRIFEKFPNRPQMIKPARLLSDFLIPKIRDSFMRQFAQLPTLEEEN--ESD-EMIAAAVSGVGVSSLPRALSIEIKRQIRGLKGNDKLNAIIYLINESNKTRMIEQ------PIIYPTRSLLSTQHQIRTERRNLRNRMAATTMSINQ--KPRLNGEIRNMDFETNRKTEEANHFDIKILQQKAEQAEIKRNQQVDDLRENHPYFDKPLFTIGRESQFRQLCRMLVEAQYKPDINSEN---PEKQTFYKLQKFFGLVTYLDWVMIFVTTTSCISMAFETP-----TKRVMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTKLKLSGDS-----PSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVGRINVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVDQRRWLDLKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDE-----YGMKRSKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVH---------ISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRE--NFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFIKAFYVRFLLRLIPKDRVGFDFTKKKDQQLFKEMCYEVELLRGGKDKEVSFHDVLTMLAYRSVDISKTXXXXXXXXXXXXXXXXXXXXXRQTIATWIERCIFRNRQ-----KHGDLKFG 5281
            A KIA  +S+ +V  +TP T + ++ L Y+    D +   +F  +   ++  +GI R                         +YL + W  F   + I   +S  +  ++L+        L+       +   YG    +RS RP I+ R++   +KF+LP+ R++ +L RS+ QV NVT+F +FFM+LYAI G+Q FG  +++HCV    + +++ I DLAIPD+ C P+   G  CP  M C+++  + + EG Y  F  F  S FTVY AAS+EGWV+++Y  MD LP +    YF ++IFFLAWLVKNVFIA++TETFAEIRVQF +MW  K  T D    K  +     W+L+ +  E +P G  PK   + +L+S  F   +++ V+ NAI  A   + HDE  +     FY  E+ FTILFN+E + KI C G++++  R + KFE ILCLG++++C+   + R   TYFQ  R+ RL+KASP+LEDF +KIF  GKKLG L++FT   +   S++S                        LQ+F                     +PN      F TF              AFMSMFQI+TQ+GW   + + +  A    L  LVA+YFV YHLFVTLIVLSLFVAVILDNLE++E++KK+KQL+ RE +   +  LP RLR+FEKFP RPQM    +  SDF +PK+R SF  QFA   +LE  +  ESD E     +   G   + +  S    RQI        LN    L+  S++TR          P    +   L  +     + R++  +   T +   Q      NG++        +K  +    DI+ LQQK + AEI RN+  +D+RENHP+FD+PLF +GR SQ R+ C+ +V ++Y    +  N     K+ F +++   G++ Y+DW M  VT  SCISM FE+P        VMN   L++++Y F ++MT E+ +K++ANG  FTPKAVVRD GGV++ FIY   +IF+A+M +   I S +  Q LMI R +RPLRI+ LVPH+RRVV E  RGF+EIL+V++L++V MF FA +GV I GGKLA CNDPT + +++C GVF +K+ VT+L++ G       P  +VPRVW NPRNFNFD++GNAML LFE LS +GW  IRD++ +R G   V++IH++VFIGC+IGLTLFVGVVIANY++N+GTALLTVDQRRW DLK R+K+ QPLH+PP+P    +S + RT                    +YDLT   +F +  A++V++N   L  PWN ++E     Y    + + A  N+    +F IE  LK+ A +F G+WQS+RN  D+++T   +IW+F+H         I V      +  +  FG++ V+LRFF+IA ++ TLKMLM TV+MSMF+S F+I A+FLL+L YA  G+ILF  VKYG  + +H NF     ++ +LFR +TGEDWN IMHDCM   PFC + E  N+W++DCGNF  ++IYFCSFY++ITYI+ N+LVA+IMENFSLFYS++EDA++SY DIRNFQ  WN +D  +K  I    V+FLLRL+ K R+  D   +KD+ LFK MCYE+E L  G  +EVSFHDVL ML+YRSVDI K+LQLEELL REELE+ IEEEVA+QTI TW+E C+ + R        G L FG
Sbjct:   83 ALKIACTISMITVCIHTPRTIELFQPLNYIILAADFISVSIFMLDSVLRIHYEGIFRCD----------------------SSYLSNRWSQFSVFISIIHLLSFLLHCYQLIDNFFPFLHLN-------YRAWYG---AIRSIRPFIIIRLIPLVVKFKLPKNRIEQLLKRSSQQVKNVTLFFVFFMTLYAIFGIQLFGR-MDYHCVQPKTDPNNVTIMDLAIPDTMCAPEGIGGYECPAPMVCMQLNLNAKGEGFYGMFNDFGASVFTVYLAASEEGWVYVLYDCMDSLPSYLAFLYFCTLIFFLAWLVKNVFIAVITETFAEIRVQFSEMWQKKEVTLDEGFRKKLEKTDDGWRLIRLDGEVEPEG--PKQKLQWMLRSMYFQCFVIIFVVINAIGNAMFVYRHDETDKPRKYNFYLFEVGFTILFNVECIIKILCYGFRNFIRRGIFKFELILCLGSSLNCVKFFYERNYFTYFQTFRLLRLIKASPILEDFVWKIFSPGKKLGGLVIFTIAFICCYSAIS------------------------LQLFY-------------------SVPN---LHHFRTFPQ------------AFMSMFQIITQEGWTDFVVEVLR-ATDDNLVPLVALYFVAYHLFVTLIVLSLFVAVILDNLEMDEELKKVKQLRAREATTSMRSTLPWRLRVFEKFPTRPQMAAMRKADSDFPMPKVRGSFTHQFAVDHSLETTDVIESDFEFPKRIMKSAGKRKISK--SGLTFRQIGSTSLRCSLNN---LLEMSDRTRQSLSNSLSFLPHFTRSSGSLYPRKDALPKSRSMTGKFLQTAVRNKQFNMYSENGDLSRPSDSAPKKNAKQGEIDIRALQQKRQLAEITRNRIEEDMRENHPFFDRPLFLVGRASQLREFCKKMVHSKYDSQDDGTNGGAKTKKRFKEIRALIGIMPYIDWAMATVTIVSCISMLFESPWPTTGENLVMNNGYLQISDYFFVLSMTFELCVKIIANGLFFTPKAVVRDVGGVMNLFIYFTSVIFLAWMPKHVEINSLA--QFLMICRAMRPLRIYTLVPHIRRVVLEFFRGFKEILLVTILMIVVMFIFASFGVQIVGGKLAACNDPTVSSRENCTGVFWQKLFVTRLEVYGKDTEAMHPKIMVPRVWTNPRNFNFDHVGNAMLALFETLSFKGWNVIRDILWSRHGPWAVVFIHIYVFIGCMIGLTLFVGVVIANYTQNRGTALLTVDQRRWHDLKARLKMAQPLHVPPKP---SESARLRTK-------------------LYDLTMSRWFNQAFALLVVLNSFTLVIPWNVEEEEQRATYVFTVTALAAFMNM----LFVIEIILKVIAYTFSGFWQSRRNRVDLLITVFGVIWIFLHFFVALPSSKIDVDVQVELKKFTYTFGYLVVILRFFTIASRNSTLKMLMLTVIMSMFRSFFIITALFLLVLFYAYTGVILFPMVKYGMAVSKHVNFRTASEALVVLFRCLTGEDWNDIMHDCMRSAPFCYWNEGMNYWETDCGNFYGAIIYFCSFYLIITYIVRNLLVAVIMENFSLFYSSEEDALLSYADIRNFQYVWNMVDQEQKRTIPVERVKFLLRLL-KGRLEVD--PEKDRILFKHMCYEMERLHNG--EEVSFHDVLYMLSYRSVDIRKSLQLEELLQREELEFIIEEEVAKQTIRTWLEGCLRKMRNPSQKDAEGVLPFG 1668

[Close]

BLAST of Voltage-dependent calcium channel vs. Ensembl Celegans
Match: unc-77 (pep chromosome:WBcel235:IV:6157312:6173040:-1 gene:WBGene00006809.1 transcript:C11D2.6a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:unc-77)

HSP 1 Score: 1238.4 bits (3203), Expect = 0.000e+0
Identity = 735/1711 (42.96%), Postives = 1028/1711 (60.08%), Query Frame = 2

Query:  284 AFKIXXXXXXXXXXXNTPETFKEYKWLFYVTYLLDIVVALLFTAEMFTKMKIKGIIRPSPYVIVRHLFFVKVSNNIENKRPHAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWLVKNVFIAILTETFAEIRVQFQQMWSPKNQT-DADSSKIFQTDGQRWKLVPV-YESKPHGLAPKLFQEIVLKSTAFNVIIMLLVLANAIVAAGLHFNHDELTQTN--GFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHCM---WYRTQLTYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEPKFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPNDWAQQLFSTFSGIYFILINLIFSFAFMSMFQILTQKGWVIVMHDTMDMAKHRGLNALVAIYFVFYHLFVTLIVLSLFVAVILDNLELEEDIKKLKQLKLREMSAETQQKLPMRLRIFEKFPNRPQMIKPARLLSDFLIPKIRDSFMRQFAQLPTLEEEN--ESDEMIAAAVSGVGVSSLPRALSIEIKRQIRGLKGNDKLN--AIIYLINESNKTRMIEQPIIYPTRSLLSTQHQIRTERRNLRNRMAATTMSINQKPRLNGEIRNMDFETNRKTEEANHFDIKILQQKAEQAEIKRNQQVDDLRENHPYFDKPLFTIGRESQFRQLCRMLVEAQYKPDINSEN---PEKQTFYKLQKFFGLVTYLDWVMIFVTTTSCISMAFETP-----TKRVMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTKLKLSGDS-----PSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVGRINVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVDQRRWLDLKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDE-----YGMKRSKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVH---------ISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRE--NFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFIKAFYVRFLLRLIPKDRVGFDFTKKKDQQLFKEMCYEVELLRGGKDKEVSFHDVLTMLAYRSVDISKTXXXXXXXXXXXXXXXXXXXXXRQTIATWIERCIFRNRQ-----KHGDLKFG 5281
            A KIA  +S+ +V  +TP T + ++ L Y+    D +   +F  +   ++  +GI R                         +YL + W  F   + I   +S  +  ++L+        L+       +   YG    +RS RP I+ R++   +KF+LP+ R++ +L RS+ QV NVT+F +FFM+LYAI G+Q FG  +++HCV    + +++ I DLAIPD+ C P+   G  CP  M C+++  + + EG Y  F  F  S FTVY AAS+EGWV+++Y  MD LP +    YF ++IFFLAWLVKNVFIA++TETFAEIRVQF +MW  K  T D    K  +     W+L+ +  E +P G  PK   + +L+S  F   +++ V+ NAI  A   + HDE  +     FY  E+ FTILFN+E + KI C G++++  R + KFE ILCLG++++C+   + R   TYFQ  R+ RL+KASP+LEDF +KIF  GKKLG L++FT   +   S++S                        LQ+F                     +PN      F TF              AFMSMFQI+TQ+GW   + + +  A    L  LVA+YFV YHLFVTLIVLSLFVAVILDNLE++E++KK+KQL+ RE +   +  LP RLR+FEKFP RPQM    +  SDF +PK+R SF  QFA   +LE  +  ESD                     E  ++I    G  K++   + +    S   R     ++  +RS+  T   ++T  RN +  M +           NG++        +K  +    DI+ LQQK + AEI RN+  +D+RENHP+FD+PLF +GR SQ R+ C+ +V ++Y    +  N     K+ F +++   G++ Y+DW M  VT  SCISM FE+P        VMN   L++++Y F ++MT E+ +K++ANG  FTPKAVVRD GGV++ FIY   +IF+A+M +   I S +  Q LMI R +RPLRI+ LVPH+RRVV E  RGF+EIL+V++L++V MF FA +GV I GGKLA CNDPT + +++C GVF +K+ VT+L++ G       P  +VPRVW NPRNFNFD++GNAML LFE LS +GW  IRD++ +R G   V++IH++VFIGC+IGLTLFVGVVIANY++N+GTALLTVDQRRW DLK R+K+ QPLH+PP+P    +S + RT                    +YDLT   +F +  A++V++N   L  PWN ++E     Y    + + A  N+    +F IE  LK+ A +F G+WQS+RN  D+++T   +IW+F+H         I V      +  +  FG++ V+LRFF+IA ++ TLKMLM TV+MSMF+S F+I A+FLL+L YA  G+ILF  VKYG  + +H NF     ++ +LFR +TGEDWN IMHDCM   PFC + E  N+W++DCGNF  ++IYFCSFY++ITYI+ N+LVA+IMENFSLFYS++EDA++SY DIRNFQ  WN +D  +K  I    V+FLLRL+ K R+  D   +KD+ LFK MCYE+E L  G  +EVSFHDVL ML+YRSVDI K+LQLEELL REELE+ IEEEVA+QTI TW+E C+ + R        G L FG
Sbjct:   83 ALKIACTISMITVCIHTPRTIELFQPLNYIILAADFISVSIFMLDSVLRIHYEGIFRCD----------------------SSYLSNRWSQFSVFISIIHLLSFLLHCYQLIDNFFPFLHLN-------YRAWYG---AIRSIRPFIIIRLIPLVVKFKLPKNRIEQLLKRSSQQVKNVTLFFVFFMTLYAIFGIQLFGR-MDYHCVQPKTDPNNVTIMDLAIPDTMCAPEGIGGYECPAPMVCMQLNLNAKGEGFYGMFNDFGASVFTVYLAASEEGWVYVLYDCMDSLPSYLAFLYFCTLIFFLAWLVKNVFIAVITETFAEIRVQFSEMWQKKEVTLDEGFRKKLEKTDDGWRLIRLDGEVEPEG--PKQKLQWMLRSMYFQCFVIIFVVINAIGNAMFVYRHDETDKPRKYNFYLFEVGFTILFNVECIIKILCYGFRNFIRRGIFKFELILCLGSSLNCVKFFYERNYFTYFQTFRLLRLIKASPILEDFVWKIFSPGKKLGGLVIFTIAFICCYSAIS------------------------LQLFY-------------------SVPN---LHHFRTFPQ------------AFMSMFQIITQEGWTDFVVEVLR-ATDDNLVPLVALYFVAYHLFVTLIVLSLFVAVILDNLEMDEELKKVKQLRAREATTSMRSTLPWRLRVFEKFPTRPQMAAMRKADSDFPMPKVRGSFTHQFAVDHSLETTDVIESD--------------------FEFPKRIMKSAGKRKISKSGLTFRQIGSTSLRCSLNNLLEKSRSM--TGKFLQTAVRNKQFNMYSE----------NGDLSRPSDSAPKKNAKQGEIDIRALQQKRQLAEITRNRIEEDMRENHPFFDRPLFLVGRASQLREFCKKMVHSKYDSQDDGTNGGAKTKKRFKEIRALIGIMPYIDWAMATVTIVSCISMLFESPWPTTGENLVMNNGYLQISDYFFVLSMTFELCVKIIANGLFFTPKAVVRDVGGVMNLFIYFTSVIFLAWMPKHVEINSLA--QFLMICRAMRPLRIYTLVPHIRRVVLEFFRGFKEILLVTILMIVVMFIFASFGVQIVGGKLAACNDPTVSSRENCTGVFWQKLFVTRLEVYGKDTEAMHPKIMVPRVWTNPRNFNFDHVGNAMLALFETLSFKGWNVIRDILWSRHGPWAVVFIHIYVFIGCMIGLTLFVGVVIANYTQNRGTALLTVDQRRWHDLKARLKMAQPLHVPPKP---SESARLRTK-------------------LYDLTMSRWFNQAFALLVVLNSFTLVIPWNVEEEEQRATYVFTVTALAAFMNM----LFVIEIILKVIAYTFSGFWQSRRNRVDLLITVFGVIWIFLHFFVALPSSKIDVDVQVELKKFTYTFGYLVVILRFFTIASRNSTLKMLMLTVIMSMFRSFFIITALFLLVLFYAYTGVILFPMVKYGMAVSKHVNFRTASEALVVLFRCLTGEDWNDIMHDCMRSAPFCYWNEGMNYWETDCGNFYGAIIYFCSFYLIITYIVRNLLVAVIMENFSLFYSSEEDALLSYADIRNFQYVWNMVDQEQKRTIPVERVKFLLRLL-KGRLEVD--PEKDRILFKHMCYEMERLHNG--EEVSFHDVLYMLSYRSVDIRKSLQLEELLQREELEFIIEEEVAKQTIRTWLEGCLRKMRNPSQKDAEGVLPFG 1634

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BLAST of Voltage-dependent calcium channel vs. Ensembl Celegans
Match: unc-77 (pep chromosome:WBcel235:IV:6157312:6183857:-1 gene:WBGene00006809.1 transcript:C11D2.6m.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:unc-77)

HSP 1 Score: 1238.02 bits (3202), Expect = 0.000e+0
Identity = 740/1718 (43.07%), Postives = 1032/1718 (60.07%), Query Frame = 2

Query:  284 AFKIXXXXXXXXXXXNTPETFKEYKWLFYVTYLLDIVVALLFTAEMFTKMKIKGIIRPSPYVIVRHLFFVKVSNNIENKRPHAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWLVKNVFIAILTETFAEIRVQFQQMWSPKNQT-DADSSKIFQTDGQRWKLVPV-YESKPHGLAPKLFQEIVLKSTAFNVIIMLLVLANAIVAAGLHFNHDELTQTN--GFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHCM---WYRTQLTYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEPKFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPNDWAQQLFSTFSGIYFILINLIFSFAFMSMFQILTQKGWVIVMHDTMDMAKHRGLNALVAIYFVFYHLFVTLIVLSLFVAVILDNLELEEDIKKLKQLKLREMSAETQQKLPMRLRIFEKFPNRPQMIKPARLLSDFLIPKIRDSFMRQFAQLPTLEEEN--ESD-EMIAAAVSGVGVSSLPRALSIEIKRQIRGLKGNDKLNAIIYLINESNKTRMIEQ------PIIYPTRSLLSTQHQIRTERRNLRNRMAATTMSINQ--KPRLNGEIRNMDFETNRKTEEANHFDIKILQQKAEQAEIKRNQQVDDLRENHPYFDKPLFTIGRESQFRQLCRMLVEAQYKPDINSEN---PEKQTFYKLQKFFGLVTYLDWVMIFVTTTSCISMAFETP-----TKRVMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTKLKLSGDS-----PSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVGRINVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVDQRRWLDLKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDE-----YGMKRSKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVH---------ISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRE--NFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFIKAFYVRFLLRLIPKDRVGFDFTKKKDQQLFKEMCYEVELLRGGKDKEVSFHDVLTMLAYRSVDISKTXXXXXXXXXXXXXXXXXXXXXRQTIATWIERCI--FRN---RQKHGDLKFG 5281
            A KIA  +S+ +V  +TP T + ++ L Y+    D +   +F  +   ++  +GI R                         +YL + W  F   + I   +S  +  ++L+        L+       +   YG    +RS RP I+ R++   +KF+LP+ R++ +L RS+ QV NVT+F +FFM+LYAI G+Q FG  +++HCV    + +++ I DLAIPD+ C P+   G  CP  M C+++  + + EG Y  F  F  S FTVY AAS+EGWV+++Y  MD LP +    YF ++IFFLAWLVKNVFIA++TETFAEIRVQF +MW  K  T D    K  +     W+L+ +  E +P G  PK   + +L+S  F   +++ V+ NAI  A   + HDE  +     FY  E+ FTILFN+E + KI C G++++  R + KFE ILCLG++++C+   + R   TYFQ  R+ RL+KASP+LEDF +KIF  GKKLG L++FT   +   S++S                        LQ+F                     +PN      F TF              AFMSMFQI+TQ+GW   + + +  A    L  LVA+YFV YHLFVTLIVLSLFVAVILDNLE++E++KK+KQL+ RE +   +  LP RLR+FEKFP RPQM    +  SDF +PK+R SF  QFA   +LE  +  ESD E     +   G   + +  S    RQI        LN    L+  S++TR          P    +   L  +     + R++  +   T +   Q      NG++        +K  +    DI+ LQQK + AEI RN+  +D+RENHP+FD+PLF +GR SQ R+ C+ +V ++Y    +  N     K+ F +++   G++ Y+DW M  VT  SCISM FE+P        VMN   L++++Y F ++MT E+ +K++ANG  FTPKAVVRD GGV++ FIY   +IF+A+M +   I S +  Q LMI R +RPLRI+ LVPH+RRVV E  RGF+EIL+V++L++V MF FA +GV I GGKLA CNDPT + +++C GVF +K+ VT+L++ G       P  +VPRVW NPRNFNFD++GNAML LFE LS +GW  IRD++ +R G   V++IH++VFIGC+IGLTLFVGVVIANY++N+GTALLTVDQRRW DLK R+K+ QPLH+PP+P    +S + RT                    +YDLT   +F +  A++V++N   L  PWN ++E     Y    + + A  N+    +F IE  LK+ A +F G+WQS+RN  D+++T   +IW+F+H         I V      +  +  FG++ V+LRFF+IA ++ TLKMLM TV+MSMF+S F+I A+FLL+L YA  G+ILF  VKYG  + +H NF     ++ +LFR +TGEDWN IMHDCM   PFC + E  N+W++DCGNF  ++IYFCSFY++ITYI+ N+LVA+IMENFSLFYS++EDA++SY DIRNFQ  WN +D  +K  I    V+FLLRL+ K R+  D   +KD+ LFK MCYE+E L  G  +EVSFHDVL ML+YRSVDI K+LQLEELL REELE+ IEEEVA+QTI TW+E C+   RN   +   G L FG
Sbjct:   89 ALKIACTISMITVCIHTPRTIELFQPLNYIILAADFISVSIFMLDSVLRIHYEGIFRCD----------------------SSYLSNRWSQFSVFISIIHLLSFLLHCYQLIDNFFPFLHLN-------YRAWYG---AIRSIRPFIIIRLIPLVVKFKLPKNRIEQLLKRSSQQVKNVTLFFVFFMTLYAIFGIQLFGR-MDYHCVQPKTDPNNVTIMDLAIPDTMCAPEGIGGYECPAPMVCMQLNLNAKGEGFYGMFNDFGASVFTVYLAASEEGWVYVLYDCMDSLPSYLAFLYFCTLIFFLAWLVKNVFIAVITETFAEIRVQFSEMWQKKEVTLDEGFRKKLEKTDDGWRLIRLDGEVEPEG--PKQKLQWMLRSMYFQCFVIIFVVINAIGNAMFVYRHDETDKPRKYNFYLFEVGFTILFNVECIIKILCYGFRNFIRRGIFKFELILCLGSSLNCVKFFYERNYFTYFQTFRLLRLIKASPILEDFVWKIFSPGKKLGGLVIFTIAFICCYSAIS------------------------LQLFY-------------------SVPN---LHHFRTFPQ------------AFMSMFQIITQEGWTDFVVEVLR-ATDDNLVPLVALYFVAYHLFVTLIVLSLFVAVILDNLEMDEELKKVKQLRAREATTSMRSTLPWRLRVFEKFPTRPQMAAMRKADSDFPMPKVRGSFTHQFAVDHSLETTDVIESDFEFPKRIMKSAGKRKISK--SGLTFRQIGSTSLRCSLNN---LLEMSDRTRQSLSNSLSFLPHFTRSSGSLYPRKDALPKSRSMTGKFLQTAVRNKQFNMYSENGDLSRPSDSAPKKNAKQGEIDIRALQQKRQLAEITRNRIEEDMRENHPFFDRPLFLVGRASQLREFCKKMVHSKYDSQDDGTNGGAKTKKRFKEIRALIGIMPYIDWAMATVTIVSCISMLFESPWPTTGENLVMNNGYLQISDYFFVLSMTFELCVKIIANGLFFTPKAVVRDVGGVMNLFIYFTSVIFLAWMPKHVEINSLA--QFLMICRAMRPLRIYTLVPHIRRVVLEFFRGFKEILLVTILMIVVMFIFASFGVQIVGGKLAACNDPTVSSRENCTGVFWQKLFVTRLEVYGKDTEAMHPKIMVPRVWTNPRNFNFDHVGNAMLALFETLSFKGWNVIRDILWSRHGPWAVVFIHIYVFIGCMIGLTLFVGVVIANYTQNRGTALLTVDQRRWHDLKARLKMAQPLHVPPKP---SESARLRTK-------------------LYDLTMSRWFNQAFALLVVLNSFTLVIPWNVEEEEQRATYVFTVTALAAFMNM----LFVIEIILKVIAYTFSGFWQSRRNRVDLLITVFGVIWIFLHFFVALPSSKIDVDVQVELKKFTYTFGYLVVILRFFTIASRNSTLKMLMLTVIMSMFRSFFIITALFLLVLFYAYTGVILFPMVKYGMAVSKHVNFRTASEALVVLFRCLTGEDWNDIMHDCMRSAPFCYWNEGMNYWETDCGNFYGAIIYFCSFYLIITYIVRNLLVAVIMENFSLFYSSEEDALLSYADIRNFQYVWNMVDQEQKRTIPVERVKFLLRLL-KGRLEVD--PEKDRILFKHMCYEMERLHNG--EEVSFHDVLYMLSYRSVDIRKSLQLEELLQREELEFIIEEEVAKQTIRTWLEGCLRKMRNPSQKDAEGVLPFG 1674

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BLAST of Voltage-dependent calcium channel vs. Ensembl Fly
Match: na (gene:FBgn0002917 transcript:FBtr0344823)

HSP 1 Score: 1504.96 bits (3895), Expect = 0.000e+0
Identity = 862/1782 (48.37%), Postives = 1137/1782 (63.80%), Query Frame = 2

Query:  209 GVEFATDDAGDLTSVNWVYTTWARCAFKIXXXXXXXXXXXNTPETFKEYKWLFYVTYLLDIVVALLFTAEMFTKMKIKGIIRPSPYVIVRHLFFVKVSNNIENKRPHAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDI------KITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWLVKNVFIAILTETFAEIRVQFQQMWSPKNQTD-ADSSKIFQTDGQRWKLVPVYESKPHGLAPKLFQEIVLKSTAFNVIIMLLVLANAIVAAGLHFNHDELTQT---NGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHC--MWYRTQLTYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEPKFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPNDWAQQLFSTFSGIYFILINLIFSFAFMSMFQILTQKGWVIVMHDTMDMAKHRGLNALVAIYFVFYHLFVTLIVLSLFVAVILDNLELEEDIKKLKQLKLREMSAETQQKLPMRLRIFEKFPNRPQMIKPARLLSDFLIPKIRDSFMRQFA-QLPTLEE--ENESDEMIAAAVSGVGVSSLPRALSIEIKRQIRGLKGNDKLNAIIYLINESNKTR-MIEQPIIYPTRSL-----LSTQHQI------RTERRNLRNRMAATTMSINQKPRLNGEIRNMDF----ETNRKTEEANHFDIKILQQKAEQAEIKRNQQVDDLRENHPYFDKPLFTIGRESQFRQLCRMLVEAQYKPDINSENP----EKQTFYK-LQKFFGLVTYLDWVMIFVTTTSCISMAFETPTKRVMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTKLKLSGDS----PSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVGRINVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVDQRRWLDLKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRENFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFIKAFYVRFLLRLIPKDRVGFDFTKKKDQQLFKEMCYEVELLRGGKDKEVSFHDVLTMLAYRSVDISKTXXXXXXXXXXXXXXXXXXXXXRQTIATWIERCIFRNR-----QKHGDLKFGLRESNEMVI--PIFDDKKEGLGLDRSRKISSGAYQTKFLSLPTLDG 5413
            G E + +++ D   + WV   W R   ++ AL+SL SVS NTP+TF+ Y  L ++T+  D  V LLFTAEM  KM I+G++                      + P  YL+  W  FD  MV  LWISI +Q FE+L+++                 K+  LS +R+PRPLI+ R LR FLKF +P++R+  I  RS+ Q+YNVT+F LFFMSLY +LGVQFFG+ + +HCV+ +  E D+       I  LAIPD+FC+    SG  C   M C+K+        G+ GF     S FTVYQAASQEGWVFIMYRA+D LP W+   YF +MIFFLAWLVKNVFIA++TETF EIRVQFQQMW  +       +S+I   +   W+LV + ++K  GLAP+    I L+S  F +++M ++LAN IV A + F HD   +      +YY ELVFT L ++E +FKI+CLGW+ Y+  S+HKFE +L  GTT+H   M+Y + LTYFQVLR+ RL+KASPMLE F +KIFG GKKLG LI+FT CLLII+SS+S                        +Q+F  + +                         F+ F           F  AFMSMFQILTQ+ WV VM +TM +   + L  LVA+YF+ YHLFVTLIVLSLFVAVILDNLEL+EDIKKLKQLK RE SAE ++ LP RLRIFEKFP+ PQM    R+ +DF++PK+R+SFM+ F  +L T +   EN    M     S V          +    ++R    + +  AI ++IN+SN  R M+    + P         L +Q  I      R +++N+R      + SI  K      + N D       N      +  DIK+LQ K +QAE++RNQ+ +DLRENHP+FD PLF + RES+FR++C+ +V A+Y  D   ++P    E++  YK L  F GLVTYLDWVMIF TT SCISM FETP  RVM+   L++AEY F + M++E+ALK+LA+G  FTPKA ++D    LD FIY++   F+ +M     I + S  Q+LMILRC+RPLRIF LVPHMR+VV+EL RGF+EIL+VS LL++ MF FA YGV ++GG+LA CNDPT + ++DCVGVF R++ VTK+KL+       P+ LVPRVWANPR FNFDNIG+AMLTLFEVLS +GW+++RDV+   VG ++ +YIH+++F+GC+IGLTLFVGVVIANYSENKGTALLTVDQRRW DLK R+K+ QPLH+PPRP  R                       K+R + YD+TQHI FKRV A++VLIN + L   W      G   ++ L   +   TF+F +E  +K  A +  GYWQS+RN YD++VT   +IW+ +   ++++     +S  FG+M V+LRFF+I GKH TLKMLM TV +S+ KS F+I  MFLL+  YALAG ILFG+VKYGE +GR ANF +    +A+LFRIVTGEDWNKIMHDCMVQPP+CT   N+W++DCGNF ASLIYFC+FY++ITYI+LN+LVAIIMENFSLFYSN+EDA++SY DIRNFQ  WN +D++++G I    V+F+LRL+ K R+  D   +KD+ LFK MCYE++ L  G+D  V+FHDV+ ML+YRSVDI K LQLEELLAREE EY +EEEVA+ TI TW+E C+ + R     ++   L  GLR +NE  +  P   + K  LG      IS+ +        PT D 
Sbjct:  339 GPEESLNESAD---IEWVNKLWVRRLMRLCALVSLTSVSLNTPKTFERYPSLQFITFASDTAVTLLFTAEMIAKMHIRGVL--------------------HGEVP--YLKDHWCQFDASMVSFLWISIILQIFEVLEIVP----------------KFSYLSIMRAPRPLIMIRFLRVFLKFSMPKSRINQIFKRSSQQIYNVTLFFLFFMSLYGLLGVQFFGE-LKNHCVMNN-TEYDLYKRPILTINSLAIPDTFCSMDPDSGYQCSPGMVCMKMDFLSSYVIGFNGFEDIATSIFTVYQAASQEGWVFIMYRAIDSLPAWRAAFYFSTMIFFLAWLVKNVFIAVITETFNEIRVQFQQMWGARGHIQKTAASQILSGNDTGWRLVTIDDNKHGGLAPETCHAI-LRSPYFRMLVMSVILANGIVTATMTFKHDGRPRDVFYERYYYIELVFTCLLDLETLFKIYCLGWRGYYKHSIHKFELLLAAGTTLHIVPMFYPSGLTYFQVLRVVRLIKASPMLEGFVYKIFGPGKKLGSLIIFTMCLLIISSSIS------------------------MQLFCFLCD-------------------------FTKFES---------FPEAFMSMFQILTQEAWVEVMDETM-IRTSKTLTPLVAVYFILYHLFVTLIVLSLFVAVILDNLELDEDIKKLKQLKFREQSAEIKETLPFRLRIFEKFPDSPQMTILHRIPNDFMLPKVRESFMKHFVIELETEDSLVENCKRPMSECWESNVVFRKQKPVRIMNKTAKVRAAGSSLRKLAITHIINDSNNQRLMLGDSAMLPVVGTKGGGGLKSQGTITHSKPWRVDQKNVR------SGSIKLKQTYEHLMENGDIAAAPRANSGRARPHDLDIKLLQAKRQQAEMRRNQREEDLRENHPFFDTPLFLVPRESRFRKICQKIVHARY--DARLKDPLTGKERKVQYKSLHNFLGLVTYLDWVMIFATTLSCISMMFETPNYRVMDHPTLQIAEYGFVIFMSLELALKILADGLFFTPKAYIKDVAAALDVFIYVVSTSFLCWMPL--NIPTNSAAQLLMILRCVRPLRIFTLVPHMRKVVYELCRGFKEILLVSTLLILLMFIFASYGVQLYGGRLARCNDPTISRREDCVGVFMRRVFVTKMKLTPGPDESYPAMLVPRVWANPRRFNFDNIGDAMLTLFEVLSFKGWLDVRDVLIKAVGPVHAVYIHIYIFLGCMIGLTLFVGVVIANYSENKGTALLTVDQRRWCDLKKRLKIAQPLHLPPRPDGR-----------------------KIRAFTYDITQHIIFKRVIAVVVLINSMLLSITWIK----GEVHTERLVIVSAVLTFVFVVEVVMKNIAFTPRGYWQSRRNRYDLLVTVAGVIWIILQTILRND-----LSYFFGFMVVILRFFTITGKHTTLKMLMLTVGVSVCKSFFIIFGMFLLVFFYALAGTILFGTVKYGEGIGRRANFGSPVTGVAMLFRIVTGEDWNKIMHDCMVQPPYCTLGNNYWETDCGNFTASLIYFCTFYVIITYIVLNLLVAIIMENFSLFYSNEEDALLSYADIRNFQNTWNIVDIHQRGVIPVRRVKFILRLL-KGRLECD--PQKDRLLFKYMCYELDKLHNGED--VTFHDVINMLSYRSVDIRKALQLEELLAREEFEYLVEEEVAKMTIRTWLEGCLKKIRAQNASKQQNSLIAGLRATNEQPVMRPNIQEDKAPLGAVDKSAISTISGAVAGACPPTSDA 1970

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BLAST of Voltage-dependent calcium channel vs. Ensembl Fly
Match: na (gene:FBgn0002917 transcript:FBtr0344822)

HSP 1 Score: 1498.03 bits (3877), Expect = 0.000e+0
Identity = 860/1785 (48.18%), Postives = 1136/1785 (63.64%), Query Frame = 2

Query:  209 GVEFATDDAGDLTSVNWVYTTWARCAFKIXXXXXXXXXXXNTPETFKEYKWLFYVTYLLDIVVALLFTAEMFTKMKIKGIIRPSPYVIVRHLFFVKVSNNIENKRPHAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDI------KITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWLVKNVFIAILTETFAEIRVQFQQMWSPKNQTD-ADSSKIFQTDGQRWKLVPVYESKPHGLAPKLFQEIVLKSTAFNVIIMLLVLANAIVAAGLHFNHDELTQT---NGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHC--MWYRTQLTYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEPKFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPNDWAQQLFSTFSGIYFILINLIFSFAFMSMFQILTQKGWVIVMHDTMDMAKHRGLNALVAIYFVFYHLFVTLIVLSLFVAVILDNLELEEDIKKLKQLKLREMSAETQQKLPMRLRIFEKFPNRPQMIKPARLLSDFLIPKIRDSFMRQFA-QLPTLEE--ENESDEMIAAAVSGVGVSSLPRALSIEIKRQIRGLKGNDKLNAIIYLINESNKTR-MIEQPIIYPTRSL-----LSTQHQI------RTERRNLRNRMAATTMS---INQKPRLNGEIRNMDF----ETNRKTEEANHFDIKILQQKAEQAEIKRNQQVDDLRENHPYFDKPLFTIGRESQFRQLCRMLVEAQYKPDINSENP----EKQTFYK-LQKFFGLVTYLDWVMIFVTTTSCISMAFETPTKRVMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTKLKLSGDS----PSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVGRINVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVDQRRWLDLKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRENFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFIKAFYVRFLLRLIPKDRVGFDFTKKKDQQLFKEMCYEVELLRGGKDKEVSFHDVLTMLAYRSVDISKTXXXXXXXXXXXXXXXXXXXXXRQTIATWIERCIFRNR-----QKHGDLKFGLRESNEMVI--PIFDDKKEGLGLDRSRKISSGAYQTKFLSLPTLDG 5413
            G E + +++ D   + WV   W R   ++ AL+SL SVS NTP+TF+ Y  L ++T+  D  V LLFTAEM  KM I+G++                      + P  YL+  W  FD  MV  LWISI +Q FE+L+++                 K+  LS +R+PRPLI+ R LR FLKF +P++R+  I  RS+ Q+YNVT+F LFFMSLY +LGVQFFG+ + +HCV+ +  E D+       I  LAIPD+FC+    SG  C   M C+K+        G+ GF     S FTVYQAASQEGWVFIMYRA+D LP W+   YF +MIFFLAWLVKNVFIA++TETF EIRVQFQQMW  +       +S+I   +   W+LV + ++K  GLAP+    I L+S  F +++M ++LAN IV A + F HD   +      +YY ELVFT L ++E +FKI+CLGW+ Y+  S+HKFE +L  GTT+H   M+Y + LTYFQVLR+ RL+KASPMLE F +KIFG GKKLG LI+FT CLLII+SS+S                        +Q+F  + +                         F+ F           F  AFMSMFQILTQ+ WV VM +TM +   + L  LVA+YF+ YHLFVTLIVLSLFVAVILDNLEL+EDIKKLKQLK RE SAE ++ LP RLRIFEKFP+ PQM    R+ +DF++PK+R+SFM+ F  +L T +   EN    M     S V          +    ++R    + +  AI ++IN+SN  R M+    + P         L +Q  I      R +++   +R    ++    I  K      + N D       N      +  DIK+LQ K +QAE++RNQ+ +DLRENHP+FD PLF + RES+FR++C+ +V A+Y  D   ++P    E++  YK L  F GLVTYLDWVMIF TT SCISM FETP  RVM+   L++AEY F + M++E+ALK+LA+G  FTPKA ++D    LD FIY++   F+ +M     I + S  Q+LMILRC+RPLRIF LVPHMR+VV+EL RGF+EIL+VS LL++ MF FA YGV ++GG+LA CNDPT + ++DCVGVF R++ VTK+KL+       P+ LVPRVWANPR FNFDNIG+AMLTLFEVLS +GW+++RDV+   VG ++ +YIH+++F+GC+IGLTLFVGVVIANYSENKGTALLTVDQRRW DLK R+K+ QPLH+PPRP  R                       K+R + YD+TQHI FKRV A++VLIN + L   W      G   ++ L   +   TF+F +E  +K  A +  GYWQS+RN YD++VT   +IW+ +   ++++     +S  FG+M V+LRFF+I GKH TLKMLM TV +S+ KS F+I  MFLL+  YALAG ILFG+VKYGE +GR ANF +    +A+LFRIVTGEDWNKIMHDCMVQPP+CT   N+W++DCGNF ASLIYFC+FY++ITYI+LN+LVAIIMENFSLFYSN+EDA++SY DIRNFQ  WN +D++++G I    V+F+LRL+ K R+  D   +KD+ LFK MCYE++ L  G+D  V+FHDV+ ML+YRSVDI K LQLEELLAREE EY +EEEVA+ TI TW+E C+ + R     ++   L  GLR +NE  +  P   + K  LG      IS+ +        PT D 
Sbjct:  339 GPEESLNESAD---IEWVNKLWVRRLMRLCALVSLTSVSLNTPKTFERYPSLQFITFASDTAVTLLFTAEMIAKMHIRGVL--------------------HGEVP--YLKDHWCQFDASMVSFLWISIILQIFEVLEIVP----------------KFSYLSIMRAPRPLIMIRFLRVFLKFSMPKSRINQIFKRSSQQIYNVTLFFLFFMSLYGLLGVQFFGE-LKNHCVMNN-TEYDLYKRPILTINSLAIPDTFCSMDPDSGYQCSPGMVCMKMDFLSSYVIGFNGFEDIATSIFTVYQAASQEGWVFIMYRAIDSLPAWRAAFYFSTMIFFLAWLVKNVFIAVITETFNEIRVQFQQMWGARGHIQKTAASQILSGNDTGWRLVTIDDNKHGGLAPETCHAI-LRSPYFRMLVMSVILANGIVTATMTFKHDGRPRDVFYERYYYIELVFTCLLDLETLFKIYCLGWRGYYKHSIHKFELLLAAGTTLHIVPMFYPSGLTYFQVLRVVRLIKASPMLEGFVYKIFGPGKKLGSLIIFTMCLLIISSSIS------------------------MQLFCFLCD-------------------------FTKFES---------FPEAFMSMFQILTQEAWVEVMDETM-IRTSKTLTPLVAVYFILYHLFVTLIVLSLFVAVILDNLELDEDIKKLKQLKFREQSAEIKETLPFRLRIFEKFPDSPQMTILHRIPNDFMLPKVRESFMKHFVIELETEDSLVENCKRPMSECWESNVVFRKQKPVRIMNKTAKVRAAGSSLRKLAITHIINDSNNQRLMLGDSAMLPVVGTKGGGGLKSQGTITHSKPWRVDQKKFGSRSIRRSVRSGSIKLKQTYEHLMENGDIAAAPRANSGRARPHDLDIKLLQAKRQQAEMRRNQREEDLRENHPFFDTPLFLVPRESRFRKICQKIVHARY--DARLKDPLTGKERKVQYKSLHNFLGLVTYLDWVMIFATTLSCISMMFETPNYRVMDHPTLQIAEYGFVIFMSLELALKILADGLFFTPKAYIKDVAAALDVFIYVVSTSFLCWMPL--NIPTNSAAQLLMILRCVRPLRIFTLVPHMRKVVYELCRGFKEILLVSTLLILLMFIFASYGVQLYGGRLARCNDPTISRREDCVGVFMRRVFVTKMKLTPGPDESYPAMLVPRVWANPRRFNFDNIGDAMLTLFEVLSFKGWLDVRDVLIKAVGPVHAVYIHIYIFLGCMIGLTLFVGVVIANYSENKGTALLTVDQRRWCDLKKRLKIAQPLHLPPRPDGR-----------------------KIRAFTYDITQHIIFKRVIAVVVLINSMLLSITWIK----GEVHTERLVIVSAVLTFVFVVEVVMKNIAFTPRGYWQSRRNRYDLLVTVAGVIWIILQTILRND-----LSYFFGFMVVILRFFTITGKHTTLKMLMLTVGVSVCKSFFIIFGMFLLVFFYALAGTILFGTVKYGEGIGRRANFGSPVTGVAMLFRIVTGEDWNKIMHDCMVQPPYCTLGNNYWETDCGNFTASLIYFCTFYVIITYIVLNLLVAIIMENFSLFYSNEEDALLSYADIRNFQNTWNIVDIHQRGVIPVRRVKFILRLL-KGRLECD--PQKDRLLFKYMCYELDKLHNGED--VTFHDVINMLSYRSVDIRKALQLEELLAREEFEYLVEEEVAKMTIRTWLEGCLKKIRAQNASKQQNSLIAGLRATNEQPVMRPNIQEDKAPLGAVDKSAISTISGAVAGACPPTSDA 1979

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BLAST of Voltage-dependent calcium channel vs. Ensembl Fly
Match: cac (gene:FBgn0263111 transcript:FBtr0332391)

HSP 1 Score: 197.208 bits (500), Expect = 6.020e-50
Identity = 181/654 (27.68%), Postives = 305/654 (46.64%), Query Frame = 2

Query: 3056 VTYLDWVMIFVTTTSCISMAFETPTKR--VMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQI-----LMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTKLKLSGDSPSFLVP----RVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEI-----------RDVIKARVGRINVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVDQRRWLDLKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSL-FVIIAMFLLMLVYALAGIILFGSVKYGEN--LGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRENFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFI 4942
            + Y D+ ++ V + S I++A E P +     N I L   +Y F    TIEM LK++  G I  P + +R+F  ++D     + +I  A     D  GS +G+ +     L +LR LRPL+    VP ++ V   +V   + ++ + ++ ++F F F+V GV +F GK   C D +K    +C G +         K   D    L+P    RVW  PR F++DN+  AMLTLF V + EGW ++           R  I+     +++ YI  F+       + +FV ++I  + E +G A L  D     + K  I  T    I  RP  R             N N+F  +V ++            F+    ++++ N + L   ++N    G    K L   N+ +T +F +E  LKI       +++   NI+D++    S++     + ++  H+S  ++  F  +    R   +  +  T+++L+ T + S FK+L +V + + +L  +YA+ G+ +FG+++Y  +  L RH NF +    I LLFR  TGE W  IM  C+         E      CG+  A   YF SF    +++MLN+ VA+IM+NF   Y   + +I+  + +  F + W   D N  G I
Sbjct:  768 LPYFDFFIMVVISMSSIALAAEDPVRENSRRNKI-LNYFDYAFTGVFTIEMLLKIVDLGVILHPGSYLREFWNIMD----AVVVICAAVSFGFDMSGSSAGQNLSTIKSLRVLRVLRPLKTIKRVPKLKAVFDCVVNSLKNVVNILIVYILFQFIFSVIGVQLFNGKFFYCTDESKHTSAECQGSY--------FKYEEDE---LLPKQELRVW-KPRAFHYDNVAAAMLTLFAVQTGEGWPQVLQHSMAATYEDRGPIQNFRIEMSIFYIVYFIVFPFFF-VNIFVALIIITFQE-QGEAELQ-DGEIDKNQKSCIDFT----IGARPLERYMPK---------NRNTFKYKVWRI-------VVSTPFEYFIMMLIVFNTLLLMMKYHNQ---GDMYEKSLKYINMGFTGMFSVETVLKIIGFGVKNFFKDPWNIFDLITVLGSIVDA---LWMEFGHDSNSINVGFLRLFRAARLIKLLRQGYTIRILLWTFVQS-FKALPYVCLLIAMLFFIYAIIGMQVFGNIRYDPDTQLNRHNNFQSFSGGIMLLFRCATGEAWPNIMLACLKGKACDDDAEKAPGEYCGSTLA-YAYFVSFIFFCSFLMLNLFVAVIMDNFD--YLTRDSSILGAHHLDEFVRIWAEYDPNATGKI 1371

HSP 2 Score: 86.2705 bits (212), Expect = 3.162e-16
Identity = 68/285 (23.86%), Postives = 131/285 (45.96%), Query Frame = 2

Query: 3068 DWVMIFVTTTSCISMAFETPTKRVMNTI---ELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKL-AIC---NDPTKTEKK---DCVGVFDRKISVTKLKLSGDSPSFLVPRVWANPRN--FNFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVGR-INVIYIHLFVFIGCLIGLTLFVGVVIANYSENK 3883
            ++ ++     +C+ +A E        T+   +L+  E  F     +E +LK+LA G +    + +R+   ++DFF+     +   +M +   IG     + L  +R LRPL++   +P ++ V+  +++    +L + +L++  +  FA+ G+  + G L   C    DP K  K+   +     D  +         ++ + +    W  P +   +FDNIG AMLT+F+ +++EGW  I       +G   N IY    + IG    L L +GV+   +S  +
Sbjct:   41 EYAVLLTIIANCVVLALEEHLPGGDKTVLAQKLEKTEAYFLCIFCVEASLKILALGLVLHKHSYLRNIWNIMDFFV-----VVTGFMTQYPQIGPEVDLRTLRAIRVLRPLKLVSGIPSLQVVLKSIIKAMAPLLQIGLLVLFAIVIFAIIGLEFYSGALHKTCYSLEDPNKLVKEGESETPCNTDNILEKATGSFVCNNTTSMCLEKWEGPNSGITSFDNIGFAMLTVFQCITMEGWTAILYWTNDALGSAFNWIYFVPLIVIGSFFMLNLVLGVLSGEFSNER 320

HSP 3 Score: 67.3958 bits (163), Expect = 1.554e-10
Identity = 59/235 (25.11%), Postives = 111/235 (47.23%), Query Frame = 2

Query: 1409 VLKSTAFNVIIMLLVLANAIVAAGLHFNHDELTQTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHCMWYRTQ--------LTYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFC---SIQIYEPKFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPNDWAQQLFSTFSGIYFILINLIFSFAFMSMF 2080
             +K+  F   +++LV  N +  A  H+       T   YYAE +F  LF  E   K++ LG + Y+  S ++F+ ++  G+    +W   +        L   ++LRIF++ K    L +    +  S + +  L+      ++I + + +QLF    ++    P+ + F+ FP A L +F ++T E W EVM + +I         AQ+       IYFI++ L  ++  +++F
Sbjct:  437 TVKTQWFYWFVIVLVFLNTVCVAVEHYGQPSFL-TEFLYYAEFIFLGLFMSEMFIKMYALGPRIYFESSFNRFDCVVISGSIFEVIWSEVKGGSFGLSVLRALRLLRIFKVTKYWSSLRNLVISLLNSMRSIISLLFLLFLFILIFALLGMQLFGGQFNLPGGTPETN-FNTFPIALLTVFQILTGEDWNEVMYQGIISQGG-----AQK--GMIYSIYFIVLVLFGNYTLLNVF 662

HSP 4 Score: 56.225 bits (134), Expect = 3.667e-7
Identity = 75/278 (26.98%), Postives = 127/278 (45.68%), Query Frame = 2

Query: 4055 KVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILASFNVTWTFIFC----IECALKITALSFIGYWQSKRNIYDMVV---TFLSLIWVFVHISVQDNHNSRVMSNNFGWMTV----LLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKYGENLGRHANFHNTFRSIALL--FRIVTGEDWNKIMHDCMVQPPFCTYRENFWQSDCGNFQASLIYFCSFYIMI---TYIMLNVLVAIIMENFS 4840
            + R W+    +  +F     ++V +N + +       + YG  +   L  F     FIF      E  +K+ AL    Y++S  N +D VV   +   +IW            S V   +FG   +    LLR F +     +L+ L+ ++L SM   + ++  +FL +L++AL G+ LFG  ++    G      NTF  IALL  F+I+TGEDWN++M+  ++                G  Q  +IY   F +++    Y +LNV +AI ++N +
Sbjct:  429 RFRFWIRHTVKTQWFYWFVIVLVFLNTVCVAV-----EHYG--QPSFLTEFLYYAEFIFLGLFMSEMFIKMYALGPRIYFESSFNRFDCVVISGSIFEVIW------------SEVKGGSFGLSVLRALRLLRIFKVTKYWSSLRNLVISLLNSMRSIISLLFLLFLFILIFALLGMQLFGG-QFNLPGGTPETNFNTF-PIALLTVFQILTGEDWNEVMYQGIISQ--------------GGAQKGMIYSIYFIVLVLFGNYTLLNVFLAIAVDNLA 671

HSP 5 Score: 55.0694 bits (131), Expect = 8.870e-7
Identity = 58/265 (21.89%), Postives = 112/265 (42.26%), Query Frame = 2

Query:  527 HAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNP---------KFKSGDSCPYSMKCVKIANSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWLVKNVFIAILTETFA------EIRVQFQQ 1276
            H+YLR+ W   D  +V+  +++   Q       I  E  L +             L  +R  RPL L   + S       Q  +K+I+ ++   +  + + +LF + ++AI+G++F+   ++  C    + E   K+      ++ CN           F   ++    ++  +  NS     G   F    F+  TV+Q  + EGW  I+Y   D L       YF+ +I   ++ + N+ + +L+  F+      E R++FQ+
Sbjct:  102 HSYLRNIWNIMDFFVVVTGFMTQYPQ-------IGPEVDLRT-------------LRAIRVLRPLKLVSGIPSL------QVVLKSII-KAMAPLLQIGLLVLFAIVIFAIIGLEFYSGALHKTCY---SLEDPNKLVKEGESETPCNTDNILEKATGSFVCNNTTSMCLEKWEGPNS-----GITSFDNIGFAMLTVFQCITMEGWTAILYWTNDALGSAFNWIYFVPLIVIGSFFMLNLVLGVLSGEFSNERNRVERRMEFQK 331

[Close]

BLAST of Voltage-dependent calcium channel vs. Ensembl Fly
Match: cac (gene:FBgn0263111 transcript:FBtr0307315)

HSP 1 Score: 196.823 bits (499), Expect = 6.326e-50
Identity = 180/655 (27.48%), Postives = 306/655 (46.72%), Query Frame = 2

Query: 3056 VTYLDWVMIFVTTTSCISMAFETPTKR--VMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQI-----LMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTKLKLSGDSPSFLVP----RVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEI-----------RDVIKARVGRINVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVDQRRWLDLKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSL-FVIIAMFLLMLVYALAGIILFGSVKYG---ENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRENFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFI 4942
            + Y D+ ++ V + S I++A E P +     N I L   +Y F    TIEM LK++  G I  P + +R+F  ++D     + +I  A     D  GS +G+ +     L +LR LRPL+    VP ++ V   +V   + ++ + ++ ++F F F+V GV +F GK   C D +K    +C G +         K   D    L+P    RVW  PR F++DN+  AMLTLF V + EGW ++           R  I+     +++ YI  F+       + +FV ++I  + E +G A L  D     + K  I  T    I  RP  R             N N+F  +V ++            F+    ++++ N + L   ++N    G    K L   N+ +T +F +E  LKI       +++   NI+D++    S++     + ++  H+S  ++  F  +    R   +  +  T+++L+ T + S FK+L +V + + +L  +YA+ G+ +FG++K G    ++ RH NF +  + + LLFR  TGE W  IM  C+         E      CG+  A   YF SF    +++MLN+ VA+IM+NF   Y   + +I+  + +  F + W   D N  G I
Sbjct:  768 LPYFDFFIMVVISMSSIALAAEDPVRENSRRNKI-LNYFDYAFTGVFTIEMLLKIVDLGVILHPGSYLREFWNIMD----AVVVICAAVSFGFDMSGSSAGQNLSTIKSLRVLRVLRPLKTIKRVPKLKAVFDCVVNSLKNVVNILIVYILFQFIFSVIGVQLFNGKFFYCTDESKHTSAECQGSY--------FKYEEDE---LLPKQELRVW-KPRAFHYDNVAAAMLTLFAVQTGEGWPQVLQHSMAATYEDRGPIQNFRIEMSIFYIVYFIVFPFFF-VNIFVALIIITFQE-QGEAELQ-DGEIDKNQKSCIDFT----IGARPLERYMPK---------NRNTFKYKVWRI-------VVSTPFEYFIMMLIVFNTLLLMMKYHNQ---GDMYEKSLKYINMGFTGMFSVETVLKIIGFGVKNFFKDPWNIFDLITVLGSIVDA---LWMEFGHDSNSINVGFLRLFRAARLIKLLRQGYTIRILLWTFVQS-FKALPYVCLLIAMLFFIYAIIGMQVFGNIKLGTVENSITRHNNFQSFIQGVMLLFRCATGEAWPNIMLACLKGKACDDDAEKAPGEYCGSTLA-YAYFVSFIFFCSFLMLNLFVAVIMDNFD--YLTRDSSILGAHHLDEFVRIWAEYDPNATGKI 1372

HSP 2 Score: 86.2705 bits (212), Expect = 3.207e-16
Identity = 68/285 (23.86%), Postives = 131/285 (45.96%), Query Frame = 2

Query: 3068 DWVMIFVTTTSCISMAFETPTKRVMNTI---ELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKL-AIC---NDPTKTEKK---DCVGVFDRKISVTKLKLSGDSPSFLVPRVWANPRN--FNFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVGR-INVIYIHLFVFIGCLIGLTLFVGVVIANYSENK 3883
            ++ ++     +C+ +A E        T+   +L+  E  F     +E +LK+LA G +    + +R+   ++DFF+     +   +M +   IG     + L  +R LRPL++   +P ++ V+  +++    +L + +L++  +  FA+ G+  + G L   C    DP K  K+   +     D  +         ++ + +    W  P +   +FDNIG AMLT+F+ +++EGW  I       +G   N IY    + IG    L L +GV+   +S  +
Sbjct:   41 EYAVLLTIIANCVVLALEEHLPGGDKTVLAQKLEKTEAYFLCIFCVEASLKILALGLVLHKHSYLRNIWNIMDFFV-----VVTGFMTQYPQIGPEVDLRTLRAIRVLRPLKLVSGIPSLQVVLKSIIKAMAPLLQIGLLVLFAIVIFAIIGLEFYSGALHKTCYSLEDPNKLVKEGESETPCNTDNILEKATGSFVCNNTTSMCLEKWEGPNSGITSFDNIGFAMLTVFQCITMEGWTAILYWTNDALGSAFNWIYFVPLIVIGSFFMLNLVLGVLSGEFSNER 320

HSP 3 Score: 67.3958 bits (163), Expect = 1.578e-10
Identity = 59/235 (25.11%), Postives = 111/235 (47.23%), Query Frame = 2

Query: 1409 VLKSTAFNVIIMLLVLANAIVAAGLHFNHDELTQTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHCMWYRTQ--------LTYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFC---SIQIYEPKFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPNDWAQQLFSTFSGIYFILINLIFSFAFMSMF 2080
             +K+  F   +++LV  N +  A  H+       T   YYAE +F  LF  E   K++ LG + Y+  S ++F+ ++  G+    +W   +        L   ++LRIF++ K    L +    +  S + +  L+      ++I + + +QLF    ++    P+ + F+ FP A L +F ++T E W EVM + +I         AQ+       IYFI++ L  ++  +++F
Sbjct:  437 TVKTQWFYWFVIVLVFLNTVCVAVEHYGQPSFL-TEFLYYAEFIFLGLFMSEMFIKMYALGPRIYFESSFNRFDCVVISGSIFEVIWSEVKGGSFGLSVLRALRLLRIFKVTKYWSSLRNLVISLLNSMRSIISLLFLLFLFILIFALLGMQLFGGQFNLPGGTPETN-FNTFPIALLTVFQILTGEDWNEVMYQGIISQGG-----AQK--GMIYSIYFIVLVLFGNYTLLNVF 662

HSP 4 Score: 56.225 bits (134), Expect = 4.085e-7
Identity = 75/278 (26.98%), Postives = 127/278 (45.68%), Query Frame = 2

Query: 4055 KVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILASFNVTWTFIFC----IECALKITALSFIGYWQSKRNIYDMVV---TFLSLIWVFVHISVQDNHNSRVMSNNFGWMTV----LLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKYGENLGRHANFHNTFRSIALL--FRIVTGEDWNKIMHDCMVQPPFCTYRENFWQSDCGNFQASLIYFCSFYIMI---TYIMLNVLVAIIMENFS 4840
            + R W+    +  +F     ++V +N + +       + YG  +   L  F     FIF      E  +K+ AL    Y++S  N +D VV   +   +IW            S V   +FG   +    LLR F +     +L+ L+ ++L SM   + ++  +FL +L++AL G+ LFG  ++    G      NTF  IALL  F+I+TGEDWN++M+  ++                G  Q  +IY   F +++    Y +LNV +AI ++N +
Sbjct:  429 RFRFWIRHTVKTQWFYWFVIVLVFLNTVCVAV-----EHYG--QPSFLTEFLYYAEFIFLGLFMSEMFIKMYALGPRIYFESSFNRFDCVVISGSIFEVIW------------SEVKGGSFGLSVLRALRLLRIFKVTKYWSSLRNLVISLLNSMRSIISLLFLLFLFILIFALLGMQLFGG-QFNLPGGTPETNFNTF-PIALLTVFQILTGEDWNEVMYQGIISQ--------------GGAQKGMIYSIYFIVLVLFGNYTLLNVFLAIAVDNLA 671

HSP 5 Score: 55.0694 bits (131), Expect = 8.351e-7
Identity = 58/265 (21.89%), Postives = 112/265 (42.26%), Query Frame = 2

Query:  527 HAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNP---------KFKSGDSCPYSMKCVKIANSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWLVKNVFIAILTETFA------EIRVQFQQ 1276
            H+YLR+ W   D  +V+  +++   Q       I  E  L +             L  +R  RPL L   + S       Q  +K+I+ ++   +  + + +LF + ++AI+G++F+   ++  C    + E   K+      ++ CN           F   ++    ++  +  NS     G   F    F+  TV+Q  + EGW  I+Y   D L       YF+ +I   ++ + N+ + +L+  F+      E R++FQ+
Sbjct:  102 HSYLRNIWNIMDFFVVVTGFMTQYPQ-------IGPEVDLRT-------------LRAIRVLRPLKLVSGIPSL------QVVLKSII-KAMAPLLQIGLLVLFAIVIFAIIGLEFYSGALHKTCY---SLEDPNKLVKEGESETPCNTDNILEKATGSFVCNNTTSMCLEKWEGPNS-----GITSFDNIGFAMLTVFQCITMEGWTAILYWTNDALGSAFNWIYFVPLIVIGSFFMLNLVLGVLSGEFSNERNRVERRMEFQK 331

[Close]

BLAST of Voltage-dependent calcium channel vs. Ensembl Fly
Match: cac (gene:FBgn0263111 transcript:FBtr0307316)

HSP 1 Score: 196.823 bits (499), Expect = 7.620e-50
Identity = 180/655 (27.48%), Postives = 306/655 (46.72%), Query Frame = 2

Query: 3056 VTYLDWVMIFVTTTSCISMAFETPTKR--VMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQI-----LMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTKLKLSGDSPSFLVP----RVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEI-----------RDVIKARVGRINVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVDQRRWLDLKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSL-FVIIAMFLLMLVYALAGIILFGSVKYG---ENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRENFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFI 4942
            + Y D+ ++ V + S I++A E P +     N I L   +Y F    TIEM LK++  G I  P + +R+F  ++D     + +I  A     D  GS +G+ +     L +LR LRPL+    VP ++ V   +V   + ++ + ++ ++F F F+V GV +F GK   C D +K    +C G +         K   D    L+P    RVW  PR F++DN+  AMLTLF V + EGW ++           R  I+     +++ YI  F+       + +FV ++I  + E +G A L  D     + K  I  T    I  RP  R             N N+F  +V ++            F+    ++++ N + L   ++N    G    K L   N+ +T +F +E  LKI       +++   NI+D++    S++     + ++  H+S  ++  F  +    R   +  +  T+++L+ T + S FK+L +V + + +L  +YA+ G+ +FG++K G    ++ RH NF +  + + LLFR  TGE W  IM  C+         E      CG+  A   YF SF    +++MLN+ VA+IM+NF   Y   + +I+  + +  F + W   D N  G I
Sbjct:  768 LPYFDFFIMVVISMSSIALAAEDPVRENSRRNKI-LNYFDYAFTGVFTIEMLLKIVDLGVILHPGSYLREFWNIMD----AVVVICAAVSFGFDMSGSSAGQNLSTIKSLRVLRVLRPLKTIKRVPKLKAVFDCVVNSLKNVVNILIVYILFQFIFSVIGVQLFNGKFFYCTDESKHTSAECQGSY--------FKYEEDE---LLPKQELRVW-KPRAFHYDNVAAAMLTLFAVQTGEGWPQVLQHSMAATYEDRGPIQNFRIEMSIFYIVYFIVFPFFF-VNIFVALIIITFQE-QGEAELQ-DGEIDKNQKSCIDFT----IGARPLERYMPK---------NRNTFKYKVWRI-------VVSTPFEYFIMMLIVFNTLLLMMKYHNQ---GDMYEKSLKYINMGFTGMFSVETVLKIIGFGVKNFFKDPWNIFDLITVLGSIVDA---LWMEFGHDSNSINVGFLRLFRAARLIKLLRQGYTIRILLWTFVQS-FKALPYVCLLIAMLFFIYAIIGMQVFGNIKLGTVENSITRHNNFQSFIQGVMLLFRCATGEAWPNIMLACLKGKACDDDAEKAPGEYCGSTLA-YAYFVSFIFFCSFLMLNLFVAVIMDNFD--YLTRDSSILGAHHLDEFVRIWAEYDPNATGKI 1372

HSP 2 Score: 81.6481 bits (200), Expect = 7.538e-15
Identity = 69/287 (24.04%), Postives = 132/287 (45.99%), Query Frame = 2

Query: 3068 DWVMIFVTTTSCISMAFETPTKRVMNTI---ELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYII--CIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKL-AIC---NDPTKTEKK---DCVGVFDRKISVTKLKLSGDSPSFLVPRVWANPRN--FNFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVGR-INVIYIHLFVFIGCLIGLTLFVGVVIANYSENK 3883
            ++ ++     +C+ +A E        T+   +L+  E  F     +E +LK+LA G +    + +R+   ++DFF+ +     IF    I VD        ++L   R LRPL++   +P ++ V+  +++    +L + +L++  +  FA+ G+  + G L   C    DP K  K+   +     D  +         ++ + +    W  P +   +FDNIG AMLT+F+ +++EGW  I       +G   N IY    + IG    L L +GV+   +++ +
Sbjct:   41 EYAVLLTIIANCVVLALEEHLPGGDKTVLAQKLEKTEAYFLCIFCVEASLKILALGLVLHKHSYLRNIWNIMDFFVVVTGAMTIFAEANIDVDL-------RMLRSFRVLRPLKLVSRIPSLQVVLKSIIKAMAPLLQIGLLVLFAIVIFAIIGLEFYSGALHKTCYSLEDPNKLVKEGESETPCNTDNILEKATGSFVCNNTTSMCLEKWEGPNSGITSFDNIGFAMLTVFQCITMEGWTAILYWTNDALGSAFNWIYFVPLIVIGSFFMLNLVLGVLSGEFAKER 320

HSP 3 Score: 67.3958 bits (163), Expect = 1.820e-10
Identity = 59/235 (25.11%), Postives = 111/235 (47.23%), Query Frame = 2

Query: 1409 VLKSTAFNVIIMLLVLANAIVAAGLHFNHDELTQTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHCMWYRTQ--------LTYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFC---SIQIYEPKFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPNDWAQQLFSTFSGIYFILINLIFSFAFMSMF 2080
             +K+  F   +++LV  N +  A  H+       T   YYAE +F  LF  E   K++ LG + Y+  S ++F+ ++  G+    +W   +        L   ++LRIF++ K    L +    +  S + +  L+      ++I + + +QLF    ++    P+ + F+ FP A L +F ++T E W EVM + +I         AQ+       IYFI++ L  ++  +++F
Sbjct:  437 TVKTQWFYWFVIVLVFLNTVCVAVEHYGQPSFL-TEFLYYAEFIFLGLFMSEMFIKMYALGPRIYFESSFNRFDCVVISGSIFEVIWSEVKGGSFGLSVLRALRLLRIFKVTKYWSSLRNLVISLLNSMRSIISLLFLLFLFILIFALLGMQLFGGQFNLPGGTPETN-FNTFPIALLTVFQILTGEDWNEVMYQGIISQGG-----AQK--GMIYSIYFIVLVLFGNYTLLNVF 662

HSP 4 Score: 55.8398 bits (133), Expect = 5.041e-7
Identity = 75/278 (26.98%), Postives = 127/278 (45.68%), Query Frame = 2

Query: 4055 KVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILASFNVTWTFIFC----IECALKITALSFIGYWQSKRNIYDMVV---TFLSLIWVFVHISVQDNHNSRVMSNNFGWMTV----LLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKYGENLGRHANFHNTFRSIALL--FRIVTGEDWNKIMHDCMVQPPFCTYRENFWQSDCGNFQASLIYFCSFYIMI---TYIMLNVLVAIIMENFS 4840
            + R W+    +  +F     ++V +N + +       + YG  +   L  F     FIF      E  +K+ AL    Y++S  N +D VV   +   +IW            S V   +FG   +    LLR F +     +L+ L+ ++L SM   + ++  +FL +L++AL G+ LFG  ++    G      NTF  IALL  F+I+TGEDWN++M+  ++                G  Q  +IY   F +++    Y +LNV +AI ++N +
Sbjct:  429 RFRFWIRHTVKTQWFYWFVIVLVFLNTVCVAV-----EHYG--QPSFLTEFLYYAEFIFLGLFMSEMFIKMYALGPRIYFESSFNRFDCVVISGSIFEVIW------------SEVKGGSFGLSVLRALRLLRIFKVTKYWSSLRNLVISLLNSMRSIISLLFLLFLFILIFALLGMQLFGG-QFNLPGGTPETNFNTF-PIALLTVFQILTGEDWNEVMYQGIISQ--------------GGAQKGMIYSIYFIVLVLFGNYTLLNVFLAIAVDNLA 671

HSP 5 Score: 54.6842 bits (130), Expect = 1.383e-6
Identity = 55/259 (21.24%), Postives = 108/259 (41.70%), Query Frame = 2

Query:  527 HAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNP---------KFKSGDSCPYSMKCVKIANSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWLVKNVFIAILTETFAEIRVQFQQ 1276
            H+YLR+ W   D  +V+   ++I             E  +D             +L + R  RPL L   + S       Q  +K+I+ ++   +  + + +LF + ++AI+G++F+   ++  C    + E   K+      ++ CN           F   ++    ++  +  NS     G   F    F+  TV+Q  + EGW  I+Y   D L       YF+ +I   ++ + N+ + +L+  FA+ R + + 
Sbjct:  102 HSYLRNIWNIMDFFVVVTGAMTIF-----------AEANIDV---------DLRMLRSFRVLRPLKLVSRIPSL------QVVLKSII-KAMAPLLQIGLLVLFAIVIFAIIGLEFYSGALHKTCY---SLEDPNKLVKEGESETPCNTDNILEKATGSFVCNNTTSMCLEKWEGPNS-----GITSFDNIGFAMLTVFQCITMEGWTAILYWTNDALGSAFNWIYFVPLIVIGSFFMLNLVLGVLSGEFAKEREKVEN 325

[Close]

BLAST of Voltage-dependent calcium channel vs. Ensembl Zebrafish
Match: nalcn (sodium leak channel, non-selective [Source:ZFIN;Acc:ZDB-GENE-050410-12])

HSP 1 Score: 1452.96 bits (3760), Expect = 0.000e+0
Identity = 831/1745 (47.62%), Postives = 1122/1745 (64.30%), Query Frame = 2

Query:  164 ERKTSHTRETQPTLPGVEFATDDA-GDLTSVNWVYTTWARCAFKIXXXXXXXXXXXNTPETFKEYKWLFYVTYLLDIVVALLFTAEMFTKMKIKGIIRPSPYVIVRHLFFVKVSNNIENKRPHAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANS--IEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWLVKNVFIAILTETFAEIRVQFQQMWSPKNQTDADSS-KIFQTDGQR-WKLVPVYESKPHGLAPKLFQEIVLKSTAFNVIIMLLVLANAIVAAGLHFNHDELTQTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHCM--WYRTQLTYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEPKFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPNDWAQQLFSTFSGIYFILINLIFSFAFMSMFQILTQKGWVIVMHDTMDMAKHRGLNALVAIYFVFYHLFVTLIVLSLFVAVILDNLELEEDIKKLKQLKLREMSAETQQKLPMRLRIFEKFPNRPQMIKPARLLSDFLIPKIRDSFMRQF----AQLPT-LEEENESDEMIAAAVSGVGVSSLPRALSIEIKRQIRGLKGNDKLNAIIY---LINESNKTRMIE-----QPIIYPTRSLLSTQHQIRTERRNLRNRMAATTMSINQKPRLNGEIRNMDFETNRKTEEANHFDIKILQQKAEQAEIKRNQQVDDLRENHPYFDKPLFTIGRESQFRQLCRMLVEAQYKP---DINSENPEKQTFYKLQKFFGLVTYLDWVMIFVTTTSCISMAFETPTKRVMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTK-----LKLSGDSPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVGRINVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVDQRRWLDLKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTY-RENFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFIKAFYVRF-LLRLIPKDRVGFDFTKKKDQQLFKEMCYEVELLRGGKDKEVSFHDVLTMLAYRSVDISKTXXXXXXXXXXXXXXXXXXXXXRQTIATWIERCIFRNR---QKHGDLKFGLRESNE 5299
            +RK S   E QP     +F  D+   D   + W+   W     +  A++S+ SV  NTP+TF+ Y  L YVT+ LD ++  L+TAEM  KM I+GII                      K  ++Y++  W  FD  MV+ LW+S+ +Q FE+ +++   +P             +G+L   R PR LI+ RV R + +F LP++R+  IL RS  Q+++VT+FLLFF+ LY ILGVQ FG   NHHCV     +  +    LAIPD+ C+P    G  CP   KCV + +      E GY+GF     S FTVY+AASQEGWVFIMYRA+D  P+W+   YF+++IFFLAWLVKNVFIA++ ETFAEIRVQFQQMW  ++ T + ++ ++F  D    W+LV V  +KPHG AP   Q++ ++S+ F++ I+ +V  + IVAA  +   D     + FY AE+ FT+LF++EA+ KIWCLG+  Y   SLHKFE +L +GTT+H     Y +Q TYFQVLR+ RL+K SP LEDF +KIFG GKKLG L++FT+ LLI+ S++S                        LQ+F  V      E + R                F+TF              AFMSMFQILTQ+GWV VM  T+ +A  +    +VAIYF+ YHLF TLI+LSLFVAVILDNLEL+ED+KKLKQLK  E +A+T++KLP+RLRIFEKFPNRPQM+K ++L SDF +P+IR+SFM+QF     Q P+ L     S    +   S        + +  ++++ +  ++  + +   I    ++    + RM+      QP     RS+LS QH IR ERR+LR+   +T+  I++   L    ++       +  +    +IK++Q+K EQAE+KR  Q ++LRENHPYFDKPLF +GRE +FR  CRM+V A++     D N+       +++L    GLVTYLDWVMI VT  SCISM FE+P  RVM+   L++ EY+F + M+IE+ LK++A+G  FTP AV+RDFGGV+D FIY++ +IF+ ++   + +   SG Q+LM+LRC RPLRIF LVP MR+VV E+++GF+EI +VS+LL+  M  FA +GV +F GKLA CNDP  + K DC G+F   +S++K     LK     P F VPRVWANPRNFNFDN+GNAML LFEVLSL+GWVE+RDVI  RVG I+ IYIH+FVF+GC+IGLTLFVGVVIAN++ENKGTALLTVDQRRW DLK R+K+ QPLH+PPRP                 EN         R  +YD+TQH +FKR  A++VL   + L   W   DE G   +  LA+ +V +TFIF +E  +K+ A+S  GYWQS+RN YD++VT L LIW+ +H ++Q+ +   +     G   ++ RFF+I GKHVTLKML+ TV++SM+KS F+I+ MFLL+L YA AG++LFG+VKYGEN+ RHANF    ++I +L RIVTGEDWNKIMHDCMVQPPFCT  +  +W++DCGN+  +LIYFCSFY++I YIMLN+LVAII+ENFSLFYS +ED ++SYND+R+FQ  WN +D  R+G I    V+F L  L  +  V  D    KD+ LFK MCYE+E L  G D  V+FHDVL+ML+YRSVDI K+LQLEELLARE+LEY IEEEVA+QTI  W+++C+ R R   Q+   +   LRES +
Sbjct:   28 KRKQSSRVEAQPM---TDFGPDETLTDSADILWINKPWVHSLLRACAIISVISVCMNTPKTFEHYPPLQYVTFALDTLLMFLYTAEMIAKMHIRGII----------------------KGENSYVKDRWCMFDGFMVVFLWVSLVLQVFEIAELVDQMSP-------------WGML---RIPRALIMIRVFRIYFRFELPRSRITNILKRSGEQIWSVTIFLLFFLLLYGILGVQMFGT-FNHHCVTNETEKEKVTWNSLAIPDTHCSPN-GEGYQCPVGFKCVDLEDYGLSRQELGYSGFNELGTSIFTVYEAASQEGWVFIMYRAIDSFPRWRSYFYFLTLIFFLAWLVKNVFIAVIIETFAEIRVQFQQMWGSRSSTTSTATTQMFHEDASGGWQLVAVDVNKPHGRAPACLQQL-MRSSVFHMFILSMVAVDVIVAASNYHRGDHKLTNDEFYLAEVAFTVLFDLEALLKIWCLGFTGYISSSLHKFESLLVVGTTLHIYPDLYHSQFTYFQVLRVVRLIKISPALEDFVYKIFGPGKKLGSLVVFTASLLIVMSAIS------------------------LQMFCFV------EDLDR----------------FTTFPR------------AFMSMFQILTQEGWVDVMDQTL-VAVGQMWAPVVAIYFILYHLFATLILLSLFVAVILDNLELDEDLKKLKQLKQSEANADTKEKLPLRLRIFEKFPNRPQMVKISKLPSDFTVPRIRESFMKQFIDRQQQDPSCLFRRLPSASSSSCDHSKRSAIEDNKYIDQKLRKSVFSIRARNLMEKEITVNKILRACTRQRMLSGSFEGQPT--KERSILSVQHHIRQERRSLRH--GSTSQRISRGKSLETLTQDHSSTVRYRNAQREDSEIKMIQEKKEQAEMKRKVQEEELRENHPYFDKPLFIVGREHRFRNFCRMIVRARFNASNTDPNTGAVNSTKYHQLYDLLGLVTYLDWVMIVVTICSCISMMFESPFTRVMHVPTLQIGEYVFVIFMSIELNLKIMADGLFFTPTAVIRDFGGVMDIFIYLVSLIFLCWL--PNNVPPESGAQLLMMLRCFRPLRIFKLVPQMRKVVREVLKGFKEIFLVSILLLTLMLVFATFGVQLFAGKLAKCNDPHISSKDDCHGIFRINVSISKNLNLKLKDGEKKPGFWVPRVWANPRNFNFDNVGNAMLALFEVLSLKGWVEVRDVIIHRVGPIHGIYIHVFVFLGCMIGLTLFVGVVIANFNENKGTALLTVDQRRWEDLKSRLKIAQPLHLPPRP-----------------ENG------GFRAKMYDITQHPFFKRGIAVLVLAQSVLLSVKW---DELG-AVTFPLATMSVVFTFIFVLEVTMKLIAMSPAGYWQSRRNRYDLLVTSLGLIWIILHFALQNAYTYMM-----GTCVIVFRFFTICGKHVTLKMLLLTVVVSMYKSFFIIVGMFLLLLCYAFAGVVLFGTVKYGENINRHANFSTAGKAITVLIRIVTGEDWNKIMHDCMVQPPFCTPDKHRYWETDCGNYAGALIYFCSFYVIIAYIMLNLLVAIIVENFSLFYSTEEDQLLSYNDLRHFQIIWNMVDDKREGVIPTSRVKFLLRLLRGRLEVDLD----KDKLLFKHMCYEMERLHNGGD--VTFHDVLSMLSYRSVDIRKSLQLEELLAREQLEYTIEEEVAKQTIRMWLKKCLKRIRAKQQQSCSIILSLRESQQ 1625

[Close]

BLAST of Voltage-dependent calcium channel vs. Ensembl Zebrafish
Match: nalcn (sodium leak channel, non-selective [Source:ZFIN;Acc:ZDB-GENE-050410-12])

HSP 1 Score: 1452.19 bits (3758), Expect = 0.000e+0
Identity = 831/1745 (47.62%), Postives = 1122/1745 (64.30%), Query Frame = 2

Query:  164 ERKTSHTRETQPTLPGVEFATDDA-GDLTSVNWVYTTWARCAFKIXXXXXXXXXXXNTPETFKEYKWLFYVTYLLDIVVALLFTAEMFTKMKIKGIIRPSPYVIVRHLFFVKVSNNIENKRPHAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANS--IEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWLVKNVFIAILTETFAEIRVQFQQMWSPKNQTDADSS-KIFQTDGQR-WKLVPVYESKPHGLAPKLFQEIVLKSTAFNVIIMLLVLANAIVAAGLHFNHDELTQTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHCM--WYRTQLTYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEPKFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPNDWAQQLFSTFSGIYFILINLIFSFAFMSMFQILTQKGWVIVMHDTMDMAKHRGLNALVAIYFVFYHLFVTLIVLSLFVAVILDNLELEEDIKKLKQLKLREMSAETQQKLPMRLRIFEKFPNRPQMIKPARLLSDFLIPKIRDSFMRQF----AQLPT-LEEENESDEMIAAAVSGVGVSSLPRALSIEIKRQIRGLKGNDKLNAIIY---LINESNKTRMIE-----QPIIYPTRSLLSTQHQIRTERRNLRNRMAATTMSINQKPRLNGEIRNMDFETNRKTEEANHFDIKILQQKAEQAEIKRNQQVDDLRENHPYFDKPLFTIGRESQFRQLCRMLVEAQYKP---DINSENPEKQTFYKLQKFFGLVTYLDWVMIFVTTTSCISMAFETPTKRVMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTK-----LKLSGDSPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVGRINVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVDQRRWLDLKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTY-RENFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFIKAFYVRF-LLRLIPKDRVGFDFTKKKDQQLFKEMCYEVELLRGGKDKEVSFHDVLTMLAYRSVDISKTXXXXXXXXXXXXXXXXXXXXXRQTIATWIERCIFRNR---QKHGDLKFGLRESNE 5299
            +RK S   E QP     +F  D+   D   + W+   W     +  A++S+ SV  NTP+TF+ Y  L YVT+ LD ++  L+TAEM  KM I+GII                      K  ++Y++  W  FD  MV+ LW+S+ +Q FE+ +++   +P             +G+L   R PR LI+ RV R + +F LP++R+  IL RS  Q+++VT+FLLFF+ LY ILGVQ FG   NHHCV     +  +    LAIPD+ C+P    G  CP   KCV + +      E GY+GF     S FTVY+AASQEGWVFIMYRA+D  P+W+   YF+++IFFLAWLVKNVFIA++ ETFAEIRVQFQQMW  ++ T + ++ ++F  D    W+LV V  +KPHG AP   Q++ ++S+ F++ I+ +V  + IVAA  +   D     + FY AE+ FT+LF++EA+ KIWCLG+  Y   SLHKFE +L +GTT+H     Y +Q TYFQVLR+ RL+K SP LEDF +KIFG GKKLG L++FT+ LLI+ S++S                        LQ+F  V      E + R                F+TF              AFMSMFQILTQ+GWV VM  T+ +A  +    +VAIYF+ YHLF TLI+LSLFVAVILDNLEL+ED+KKLKQLK  E +A+T++KLP+RLRIFEKFPNRPQM+K ++L SDF +P+IR+SFM+QF     Q P+ L     S    +   S        + +  ++++ +  ++  + +   I    ++    + RM+      QP     RS+LS QH IR ERR+LR+   +T+  I++   L    ++       +  +    +IK++Q+K EQAE+KR  Q ++LRENHPYFDKPLF +GRE +FR  CRM+V A++     D N+       +++L    GLVTYLDWVMI VT  SCISM FE+P  RVM+   L++ EY+F + M+IE+ LK++A+G  FTP AV+RDFGGV+D FIY++ +IF+ ++   + +   SG Q+LM+LRC RPLRIF LVP MR+VV E+++GF+EI +VS+LL+  M  FA +GV +F GKLA CNDP  + K DC G+F   +S++K     LK     P F VPRVWANPRNFNFDN+GNAML LFEVLSL+GWVE+RDVI  RVG I+ IYIH+FVF+GC+IGLTLFVGVVIAN++ENKGTALLTVDQRRW DLK R+K+ QPLH+PPRP                 EN         R  +YD+TQH +FKR  A++VL   + L   W   DE G   +  LA+ +V +TFIF +E  +K+ A+S  GYWQS+RN YD++VT L LIW+ +H ++Q+ +   +     G   ++ RFF+I GKHVTLKML+ TV++SM+KS F+I+ MFLL+L YA AG++LFG+VKYGEN+ RHANF    ++I +L RIVTGEDWNKIMHDCMVQPPFCT  +  +W++DCGN+  +LIYFCSFY++I YIMLN+LVAII+ENFSLFYS +ED ++SYND+R+FQ  WN +D  R+G I    V+F L  L  +  V  D    KD+ LFK MCYE+E L  G D  V+FHDVL+ML+YRSVDI K+LQLEELLARE+LEY IEEEVA+QTI  W+++C+ R R   Q+   +   LRES +
Sbjct:    3 KRKQSSRVEAQPM---TDFGPDETLTDSADILWINKPWVHSLLRACAIISVISVCMNTPKTFEHYPPLQYVTFALDTLLMFLYTAEMIAKMHIRGII----------------------KGENSYVKDRWCMFDGFMVVFLWVSLVLQVFEIAELVDQMSP-------------WGML---RIPRALIMIRVFRIYFRFELPRSRITNILKRSGEQIWSVTIFLLFFLLLYGILGVQMFGT-FNHHCVTNETEKEKVTWNSLAIPDTHCSPN-GEGYQCPVGFKCVDLEDYGLSRQELGYSGFNELGTSIFTVYEAASQEGWVFIMYRAIDSFPRWRSYFYFLTLIFFLAWLVKNVFIAVIIETFAEIRVQFQQMWGSRSSTTSTATTQMFHEDASGGWQLVAVDVNKPHGRAPACLQQL-MRSSVFHMFILSMVAVDVIVAASNYHRGDHKLTNDEFYLAEVAFTVLFDLEALLKIWCLGFTGYISSSLHKFESLLVVGTTLHIYPDLYHSQFTYFQVLRVVRLIKISPALEDFVYKIFGPGKKLGSLVVFTASLLIVMSAIS------------------------LQMFCFV------EDLDR----------------FTTFPR------------AFMSMFQILTQEGWVDVMDQTL-VAVGQMWAPVVAIYFILYHLFATLILLSLFVAVILDNLELDEDLKKLKQLKQSEANADTKEKLPLRLRIFEKFPNRPQMVKISKLPSDFTVPRIRESFMKQFIDRQQQDPSCLFRRLPSASSSSCDHSKRSAIEDNKYIDQKLRKSVFSIRARNLMEKEITVNKILRACTRQRMLSGSFEGQPT--KERSILSVQHHIRQERRSLRH--GSTSQRISRGKSLETLTQDHSSTVRYRNAQREDSEIKMIQEKKEQAEMKRKVQEEELRENHPYFDKPLFIVGREHRFRNFCRMIVRARFNASNTDPNTGAVNSTKYHQLYDLLGLVTYLDWVMIVVTICSCISMMFESPFTRVMHVPTLQIGEYVFVIFMSIELNLKIMADGLFFTPTAVIRDFGGVMDIFIYLVSLIFLCWL--PNNVPPESGAQLLMMLRCFRPLRIFKLVPQMRKVVREVLKGFKEIFLVSILLLTLMLVFATFGVQLFAGKLAKCNDPHISSKDDCHGIFRINVSISKNLNLKLKDGEKKPGFWVPRVWANPRNFNFDNVGNAMLALFEVLSLKGWVEVRDVIIHRVGPIHGIYIHVFVFLGCMIGLTLFVGVVIANFNENKGTALLTVDQRRWEDLKSRLKIAQPLHLPPRP-----------------ENG------GFRAKMYDITQHPFFKRGIAVLVLAQSVLLSVKW---DELG-AVTFPLATMSVVFTFIFVLEVTMKLIAMSPAGYWQSRRNRYDLLVTSLGLIWIILHFALQNAYTYMM-----GTCVIVFRFFTICGKHVTLKMLLLTVVVSMYKSFFIIVGMFLLLLCYAFAGVVLFGTVKYGENINRHANFSTAGKAITVLIRIVTGEDWNKIMHDCMVQPPFCTPDKHRYWETDCGNYAGALIYFCSFYVIIAYIMLNLLVAIIVENFSLFYSTEEDQLLSYNDLRHFQIIWNMVDDKREGVIPTSRVKFLLRLLRGRLEVDLD----KDKLLFKHMCYEMERLHNGGD--VTFHDVLSMLSYRSVDIRKSLQLEELLAREQLEYTIEEEVAKQTIRMWLKKCLKRIRAKQQQSCSIILSLRESQQ 1600

[Close]

BLAST of Voltage-dependent calcium channel vs. Ensembl Zebrafish
Match: nalcn (sodium leak channel, non-selective [Source:ZFIN;Acc:ZDB-GENE-050410-12])

HSP 1 Score: 290.812 bits (743), Expect = 6.750e-87
Identity = 176/419 (42.00%), Postives = 242/419 (57.76%), Query Frame = 2

Query:  164 ERKTSHTRETQPTLPGVEFATDDA-GDLTSVNWVYTTWARCAFKIXXXXXXXXXXXNTPETFKEYKWLFYVTYLLDIVVALLFTAEMFTKMKIKGIIRPSPYVIVRHLFFVKVSNNIENKRPHAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANS--IEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWLVKNVFIAILTETFAEIRVQFQQMWS-PKNQTDADSSKIFQTDGQ-RWKLVPVYESKPHGLAPKLFQE 1405
            +RK S   E QP     +F  D+   D   + W+   W     +  A++S+ SV  NTP+TF+ Y  L YVT+ LD ++  L+TAEM  KM I+GII                      K  ++Y++  W  FD  MV+ LW+S+ +Q FE+ +++   +P             +G+L   R PR LI+ RV R + +F LP++R+  IL RS  Q+++VT+FLLFF+ LY ILGVQ FG   NHHCV     +  +    LAIPD+ C+P    G  CP   KCV + +      E GY+GF     S FTVY+AASQEGWVFIMYRA+D  P+W+   YF+++IFFLAWLVKNVFIA++ ETFAEIRVQFQQMW    + T   ++++F  D    W+LV V  +KPHG AP   Q+
Sbjct:    3 KRKQSSRVEAQPM---TDFGPDETLTDSADILWINKPWVHSLLRACAIISVISVCMNTPKTFEHYPPLQYVTFALDTLLMFLYTAEMIAKMHIRGII----------------------KGENSYVKDRWCMFDGFMVVFLWVSLVLQVFEIAELVDQMSP-------------WGML---RIPRALIMIRVFRIYFRFELPRSRITNILKRSGEQIWSVTIFLLFFLLLYGILGVQMFGT-FNHHCVTNETEKEKVTWNSLAIPDTHCSPN-GEGYQCPVGFKCVDLEDYGLSRQELGYSGFNELGTSIFTVYEAASQEGWVFIMYRAIDSFPRWRSYFYFLTLIFFLAWLVKNVFIAVIIETFAEIRVQFQQMWGSRSSTTSTATTQMFHEDASGGWQLVAVDVNKPHGRAPACLQK 378

[Close]

BLAST of Voltage-dependent calcium channel vs. Ensembl Zebrafish
Match: nalcn (sodium leak channel, non-selective [Source:ZFIN;Acc:ZDB-GENE-050410-12])

HSP 1 Score: 290.812 bits (743), Expect = 1.476e-86
Identity = 176/419 (42.00%), Postives = 242/419 (57.76%), Query Frame = 2

Query:  164 ERKTSHTRETQPTLPGVEFATDDA-GDLTSVNWVYTTWARCAFKIXXXXXXXXXXXNTPETFKEYKWLFYVTYLLDIVVALLFTAEMFTKMKIKGIIRPSPYVIVRHLFFVKVSNNIENKRPHAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANS--IEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWLVKNVFIAILTETFAEIRVQFQQMWS-PKNQTDADSSKIFQTDGQ-RWKLVPVYESKPHGLAPKLFQE 1405
            +RK S   E QP     +F  D+   D   + W+   W     +  A++S+ SV  NTP+TF+ Y  L YVT+ LD ++  L+TAEM  KM I+GII                      K  ++Y++  W  FD  MV+ LW+S+ +Q FE+ +++   +P             +G+L   R PR LI+ RV R + +F LP++R+  IL RS  Q+++VT+FLLFF+ LY ILGVQ FG   NHHCV     +  +    LAIPD+ C+P    G  CP   KCV + +      E GY+GF     S FTVY+AASQEGWVFIMYRA+D  P+W+   YF+++IFFLAWLVKNVFIA++ ETFAEIRVQFQQMW    + T   ++++F  D    W+LV V  +KPHG AP   Q+
Sbjct:   28 KRKQSSRVEAQPM---TDFGPDETLTDSADILWINKPWVHSLLRACAIISVISVCMNTPKTFEHYPPLQYVTFALDTLLMFLYTAEMIAKMHIRGII----------------------KGENSYVKDRWCMFDGFMVVFLWVSLVLQVFEIAELVDQMSP-------------WGML---RIPRALIMIRVFRIYFRFELPRSRITNILKRSGEQIWSVTIFLLFFLLLYGILGVQMFGT-FNHHCVTNETEKEKVTWNSLAIPDTHCSPN-GEGYQCPVGFKCVDLEDYGLSRQELGYSGFNELGTSIFTVYEAASQEGWVFIMYRAIDSFPRWRSYFYFLTLIFFLAWLVKNVFIAVIIETFAEIRVQFQQMWGSRSSTTSTATTQMFHEDASGGWQLVAVDVNKPHGRAPACLQK 403

[Close]

BLAST of Voltage-dependent calcium channel vs. Ensembl Zebrafish
Match: cacna1bb (calcium channel, voltage-dependent, N type, alpha 1B subunit, b [Source:ZFIN;Acc:ZDB-GENE-090514-4])

HSP 1 Score: 182.185 bits (461), Expect = 3.466e-45
Identity = 179/715 (25.03%), Postives = 321/715 (44.90%), Query Frame = 2

Query: 2864 KRNQQVDDLRENHPYFDKP---LFTIGRESQFRQLCRMLVEAQYKPDINSENPEKQTFYKLQKFFGLVTYLDWVMIFVTTTSCISMAFETPTK-RVMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGS-GKQI-----LMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTKLKLSGDSPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGW-----------VEIRDVIKARVGRINVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTAL----LTVDQRRWLDLKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSL-FVIIAMFLLMLVYALAGIILFGSVKYGEN---LGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRENFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSID 4921
            +  + +D+L +N P    P   +F  G  +  R+LC  +V                           + Y +  ++ V T S I++A E P +        LK  +Y+F    T EM +K++  G +  P +  RD   +LDF +  +    VA+        SG+ GK I     L +LR LRPL+    +P ++ V   +V   + +L + ++ ++FMF FAV  V +F GK   C D +K  +KDC G F        L+   D  +   PR W    +F++DN+  A LTLF V + EGW            E +          ++ Y+  F+       + +FV ++I  + E    A+    L  ++R  +D     K       P    M QD            +NS+     + + W + ++    +  ++  M+ IN + L   ++   +       +L   N+ +T +F +EC LK+ A   + Y +   NI+D V    S+  + V   ++D    + ++ +F  +    R   +  +  T+++L+ T + S FK+L +V + + +L  +YA+ G+ +FG++        +  H NF   F+++ LLFR  TGE W++IM  C+ +  +C     +   +CG+   +  YF SF  + +++MLN+ VA+IM+NF   Y   + +I+  + +  F + W   D
Sbjct: 1050 EEKKDLDELNQNAPKHILPYSSMFVFGPTNPVRRLCHYVVN--------------------------LRYFEMCILTVITMSSIALAAEDPVQAHAPRNDVLKYLDYVFTGVFTFEMVIKMIDLGLLLHPGSYFRDLWNILDFIV--VSGALVAFAC------SGTKGKDINTIKSLRVLRVLRPLKTIKRLPKLKAVFDCVVNSLKNVLNILIVYILFMFIFAVIAVQLFKGKFFHCTDESKALEKDCRGQF--------LEYGSDGVAMTQPREWKK-YDFHYDNVLWAFLTLFTVSTGEGWPLVLKHSVDATYEDQGPSPGYRMETSIFYVVYFIVFPFFF-VNIFVALIIITFQEQGDKAMSECSLEKNERACIDFAINAK-------PLTRYMPQD------------KNSY-----QYKMWKFVVSTPFEYSILT--MIAINTVVLMMKFHGAPK---PYEDMLKWLNIIFTALFTLECVLKVIAFGPLNYLKEAWNIFDFVTVLGSITDILV-TEIKD----KRINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQS-FKALPYVCLLIAMLFFIYAIIGMQVFGNIALNNEDSAINIHNNFRTFFQALMLLFRSATGEAWHEIMLACLSE-RYCDIESGYSGKECGS-DFAYFYFVSFIFLCSFLMLNLFVAVIMDNFE--YLTRDASILGPHHLDEFIRVWAEYD 1681

HSP 2 Score: 78.1814 bits (191), Expect = 1.295e-13
Identity = 135/631 (21.39%), Postives = 245/631 (38.83%), Query Frame = 2

Query:  383 LDIVVALLFTAEMFTKMKIKGIIRPSPYVIVRHLFFVKVSNNIENKRPHAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILH---RSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQS-ANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVS-------------YFISMIFFLAWLVKNVFIAILTETFAEIRVQFQQMWSPKNQTDADSSKIFQTDGQRWKLVPVYESKP---------HGLAPKLFQEIVLKSTAFNVIIMLLVLANAIVAAGLHFNHDELTQTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHCMWY-----RTQLTYFQVLRIFRLMKASPMLEDFCFKIF-----GSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEPK-----FDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMID----------AKKIPNDWAQQLFSTFSGI-YFILINLIFSFAFMSMFQILTQKGWVIVMH 2119
            LD V   +FT EM  KM   G++                        P +Y R  W   D I+V    ++                   +C        K   ++T++S R L + R L++    RLP  ++KA+      S   V N+ +  + FM ++A++ VQ F      HC  +S A E D +                 G    Y    V +    E +     +    ++F T++  ++ EGW  ++  ++D   + +G S             YFI   FF      N+F+A++  TF E             Q D   S+      +R  +     +KP         +    K+++ +V  ST F   I+ ++  N +V   + F+       +   +  ++FT LF +E V K+   G  +Y   + + F+F+  LG+    +       R  L++ ++ R  RL+K   + + +  +I       S K L  + L  + L  I + + +Q+F +I +          + F  F +A + +F   T E W E+M   + +           K+  +D+A   F +F  +  F+++NL F    M  F+ LT+   ++  H
Sbjct: 1128 LDYVFTGVFTFEMVIKMIDLGLLL----------------------HPGSYFRDLWNILDFIVVSGALVAF------------------ACS-----GTKGKDINTIKSLRVLRVLRPLKTIK--RLP--KLKAVFDCVVNSLKNVLNILIVYILFMFIFAVIAVQLFKGKF-FHCTDESKALEKDCR-----------------GQFLEYGSDGVAMTQPREWKKYDFHYDNVLWAFLTLFTVSTGEGWPLVLKHSVDATYEDQGPSPGYRMETSIFYVVYFIVFPFFFV----NIFVALIIITFQE-------------QGDKAMSECSLEKNERACIDFAINAKPLTRYMPQDKNSYQYKMWKFVV--STPFEYSILTMIAINTVVLM-MKFHGAPKPYEDMLKWLNIIFTALFTLECVLKVIAFGPLNYLKEAWNIFDFVTVLGSITDILVTEIKDKRINLSFLRLFRAARLIKL--LRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGNIALNNEDSAINIHNNFRTFFQALMLLFRSATGEAWHEIMLACLSERYCDIESGYSGKECGSDFAYFYFVSFIFLCSFLMLNL-FVAVIMDNFEYLTRDASILGPH 1668

HSP 3 Score: 77.7962 bits (190), Expect = 1.432e-13
Identity = 60/241 (24.90%), Postives = 114/241 (47.30%), Query Frame = 2

Query: 1391 KLFQEIVLKSTAFNVIIMLLVLANAIVAAGLHFNHDELTQTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHCMWYRTQ---------LTYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEPKFD--RFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPNDWAQQLFSTFSGIYFILINLIFSFAFMSMF 2080
            + F   ++K+ +F  I++ LV  N +  A +H++  E   T   Y AE VF  LF  E   K++ LG ++Y++ S + F+F + +G+    +W   Q         L   ++LRIF++ K    L +    +  S K +  L+      +++ + + +QLF     +E +     F +FP A + +F ++T E W  VM   +     +           FS +YFI++ L  ++  +++F
Sbjct:  467 RFFIRRMVKAQSFYWIVLCLVGLNTMCVAIVHYDQPEWL-TKALYLAEFVFLGLFLTEMTLKMYGLGPRNYFHSSFNCFDFGVIVGSIFEVIWAAIQPGASFGISVLRALRLLRIFKVTKYWNSLRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNFEDETPTTNFDSFPAAIMTVFQILTGEDWNAVMYHGIESQGGVRG-------GMFSSVYFIVLTLFGNYTLLNVF 699

HSP 4 Score: 73.9442 bits (180), Expect = 2.165e-12
Identity = 69/284 (24.30%), Postives = 123/284 (43.31%), Query Frame = 2

Query: 3071 WVMIFVTTTSCISMAFETPTKRVMNTI---ELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTKLKLSGDSPSFLVP------RVWANPRNF---NFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVGRI-NVIYIHLFVFIGCLIGLTLFVGVVIANYSENK 3883
            ++++     +CI +A E     +  T     L   E  F      E  +K++A GF+F   + +R+   ++DF + +  I+         T+GS    + L  +R LRPL++   +P ++ V+  +++    +L + +LL   +  FA+ GV  + GK              C  V D            + PS   P        W  P NF   NFDNI  A+LT+F+ +++EGW ++        G   N +Y    + IG    L L +GV+   +++ +
Sbjct:   81 YLILTTIIANCIVLALEQHLPALDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFVFHKDSYLRNGWNIMDFVVVVTGIL--------TTVGSQFDLRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMVPLLQIGLLLFFAIVMFAIIGVEFYMGKFHFT----------CFKV-DTGEKAVDYPCGAEPPSRSCPVGTNCTEYWKGP-NFGITNFDNILFAILTVFQCITMEGWTDVLYHTNDAAGNTWNWLYFIPLIIIGSFFMLNLVLGVLSGEFAKER 344

HSP 5 Score: 61.2326 bits (147), Expect = 1.791e-8
Identity = 56/251 (22.31%), Postives = 101/251 (40.24%), Query Frame = 2

Query:  530 AYLRHFWGCFDTIMVICLWISITIQTFEL--LKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWLVKNVFIAILTETFAEIRVQFQQ 1276
            +YLR+ W   D ++V+   ++     F+L  L+ ++   PL              L+S + S     L  VL+S +K  +P              +  + + L F + ++AI+GV+F+    +  C      E  +     A P S          SCP    C +         G   F    F+  TV+Q  + EGW  ++Y   D         YFI +I   ++ + N+ + +L+  FA+ R + ++
Sbjct:  142 SYLRNGWNIMDFVVVVTGILTTVGSQFDLRTLRAVRVLRPLK-------------LVSGIPS-----LQVVLKSIMKAMVP--------------LLQIGLLLFFAIVMFAIIGVEFYMGKFHFTCFKVDTGEKAVDYPCGAEPPS---------RSCPVGTNCTEYWKG--PNFGITNFDNILFAILTVFQCITMEGWTDVLYHTNDAAGNTWNWLYFIPLIIIGSFFMLNLVLGVLSGEFAKERERVEK 349

HSP 6 Score: 58.151 bits (139), Expect = 1.313e-7
Identity = 58/212 (27.36%), Postives = 99/212 (46.70%), Query Frame = 2

Query: 4226 IFCIECALKITALSFIGYWQSKRNIYD---MVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTV----LLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRENFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFS 4840
            +F  E  LK+  L    Y+ S  N +D   +V +   +IW  +               +FG   +    LLR F +     +L+ L+ ++L SM   + ++  +FL ++V+AL G+ LFG     E+     NF +   +I  +F+I+TGEDWN +M+  +         E+      G F  S +YF    +   Y +LNV +AI ++N +
Sbjct:  519 LFLTEMTLKMYGLGPRNYFHSSFNCFDFGVIVGSIFEVIWAAIQPGA-----------SFGISVLRALRLLRIFKVTKYWNSLRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNFEDETPTTNFDSFPAAIMTVFQILTGEDWNAVMYHGI---------ESQGGVRGGMF--SSVYFIVLTLFGNYTLLNVFLAIAVDNLA 708

[Close]

BLAST of Voltage-dependent calcium channel vs. Ensembl Xenopus
Match: NALCN (sodium leak channel, non selective [Source:NCBI gene;Acc:100492286])

HSP 1 Score: 1471.06 bits (3807), Expect = 0.000e+0
Identity = 859/1920 (44.74%), Postives = 1191/1920 (62.03%), Query Frame = 2

Query:  164 ERKTSHTRETQPTLPGVEFATDDA-GDLTSVNWVYTTWARCAFKIXXXXXXXXXXXNTPETFKEYKWLFYVTYLLDIVVALLFTAEMFTKMKIKGIIRPSPYVIVRHLFFVKVSNNIENKRPHAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIA--NSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWLVKNVFIAILTETFAEIRVQFQQMWSPKNQTDADSS-KIFQTDGQR-WKLVPVYESKPHGLAPKLFQEIVLKSTAFNVIIMLLVLANAIVAAGLHFNHDELT-QTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHCM--WYRTQLTYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEPKFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPNDWAQQLFSTFSGIYFILINLIFSFAFMSMFQILTQKGWVIVMHDTMDMAKHRGLNALVAIYFVFYHLFVTLIVLSLFVAVILDNLELEEDIKKLKQLKLREMSAETQQKLPMRLRIFEKFPNRPQMIKPARLLSDFLIPKIRDSFMRQFAQLPTLEEENESDEMIA------------AAVSGVGVSSLPRALSIEIKRQIRGLKGN---DKLNAIIYLINESNKTRMIE-----QPIIYPTRSLLSTQHQIRTERRNLRNRMAATTMSINQKPRLNGEIRNMDFETNRKTEEANHFDIKILQQKAEQAEIKRNQQVDDLRENHPYFDKPLFTIGRESQFRQLCRMLVEAQY---KPDINSENPEKQTFYKLQKFFGLVTYLDWVMIFVTTTSCISMAFETPTKRVMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTK-----LKLSGDSPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVGRINVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVDQRRWLDLKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTY-RENFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFIKAFYVRF-LLRLIPKDRVGFDFTKKKDQQLFKEMCYEVELLRGGKDKEVSFHDVLTMLAYRSVDISKTXXXXXXXXXXXXXXXXXXXXXRQTIATWIERCIFRNRQKHGDLKFGLRESNEMVIPIFDDKKEGLGLDRSRKISSGAYQTKFLSLPTLDGRQNTSDGSLPSSGITIGRLNDHLKNQPMGFKRRRSVKKNSSTNQTLTEVSEDELNDELNDIVPTQDPDLTPNQLPSLSDSHVPIENSISS-------RSEDK----HLTELVD-ADC-HEVKSWWHVQINTD 5770
            +RK S   E QP     +F  D++  D   + W+   W     +I A++S+ SV  NTP+TF+ Y  L YVT+ LD ++  L+TAEM  KM I+GI+                      K   +Y++  W  FD  MV CLW+S+ +Q FE+ K++   +P             +G+L   R PRPLI+ R  R + +F LP+TR+  IL RS  Q+++V++FLLFF+ LY ILGVQ FG     HCV       ++   +LAIPD+ C+P+   G  CP   +CV +        E GY+GF     S FTVY+AASQEGWVF+MYRA+D  P+W+   YFI++IFFLAWLVKNVFIA++ ETFAEIRVQFQQMW  ++ T + ++ ++F  D    W+LV V  +KP G AP   Q++ ++S+ F++ I+ +V  + IVAA  ++  +    Q + FY AE+ FT+LF++EA+ KIWCLG+  Y   SLHKFE +L +GTT+H     Y +Q TYFQVLR+ RL+K SP LEDF +KIFG GKKLG L++FT+ LLI+ S++SLQ+FC ++    + DR                                          F+TF              AFMSMFQILTQ+GWV VM  T++   H     +VAIYF+ YHLF TLI+LSLFVAVILDNLEL+ED+KKLKQLK  E +A+T++KLP+RLRIFEKFPNRPQM+K ++L SDF +PKIR+SFM+QF       ++ ++  ++             +  SGV  +   + +  ++++ +  ++     +K  A+  ++ +  + RM+      QP     RS+LS QH IR ERR+LR+   + +  I++   L    ++       +  +    +IK++Q+K EQAE+KR  Q ++LRENHPYFDKPLF +GRE +FR  CR++V A++   K D  +   +   +++L    GLVTYLDWVMI VT  SCISM FE+P +RVM+T  L++AEY+F + M+IE+ LK++A+G  FTP AV+RDFGGV+D FIY++ +IF+ +M   + + + SG Q+LM+LRCLRPLRIF LVP MR+VV EL  GF+EI +VS+LL+  M  FA +GV +F GKLA CNDP    ++DC G+F   +SV+K     LK     P F VPRVWANPRNFNFDN+GNAML LFEVLSL+GWVE+RDVI  RVG I+ IYIH+FVF+GC+IGLTLFVGVVIAN++ENKGTALLTVDQRRW DLK R+K+ QPLH+PPRP           DN+              R  +YD+TQH +FKR  A++VL   + L   W+ +D   +     LA+ +V +TFIF +E  +KITA+S  G+WQS+RN YD++VT L +IWV +H ++ + +   +     G   ++ RFFSI GKHVTLKML+ TV++SM+KS F+I+ MFLL+L YA AG++LFG+VKYGEN+ RHANF    ++I +LFRIVTGEDWNKIMHDCMVQPPFCT     +W++DCGN+  +L+YFCSFY++I YIMLN+LVAII+ENFSLFYS +ED ++S ND+R++Q  WN +D  R+G I AF V+F L  L  +  V  D    KD+ LFK MCYE+E L  G D  V+FHDVL+ML+YRSVDI K+LQLEELLARE+LEY IEEEVA+QTI  W+++C+ R R K        ++S  ++  + + +++ L              ++FL+ P+++  Q + D                     M    + + +  +S+ Q L   +  +      D +    P     Q   L  +  PI +S+SS       RS  K     +  + D A C  EVK WW  Q+  +
Sbjct:   11 KRKQSSRVEAQPV---TDFGPDESLSDNADILWINKPWVHSLLRICAIISVISVCMNTPKTFEHYPPLQYVTFALDTLLMFLYTAEMIAKMHIRGIV----------------------KGDTSYVKDRWCVFDGFMVFCLWVSLVLQVFEIAKIVDQMSP-------------WGML---RIPRPLIMIRAFRIYFRFELPRTRITNILKRSGEQIWSVSIFLLFFLLLYGILGVQMFGT-FTFHCVTNDTVHGNLTWNNLAIPDTHCSPE-GEGYQCPRGFRCVDLKELGLSRQELGYSGFNEIGTSIFTVYEAASQEGWVFLMYRAIDSFPRWRSYFYFITLIFFLAWLVKNVFIAVIIETFAEIRVQFQQMWGSRSSTTSTATTQMFHEDAAGGWQLVAVDVNKPQGRAPACLQKM-MRSSIFHMFILSMVAVDVIVAASNYYKGENFKRQYDEFYLAEVAFTMLFDLEALLKIWCLGFTGYISSSLHKFELLLVVGTTLHIYPDLYHSQFTYFQVLRVVRLIKISPALEDFVYKIFGPGKKLGSLVVFTASLLIVMSAISLQMFCFVE----ELDR------------------------------------------FTTFPR------------AFMSMFQILTQEGWVDVMDQTLNAVGHM-WAPVVAIYFILYHLFATLILLSLFVAVILDNLELDEDLKKLKQLKQSEANADTKEKLPLRLRIFEKFPNRPQMVKISKLPSDFTVPKIRESFMKQFID----RQQQDTSCLLRRLPSASSSSCDHSKRSGVEEN---KYIDQKLRKSVFSIRARNLLEKETAVNKILRDCTRQRMLSGSFEGQPA--KERSILSVQHHIRQERRSLRH--GSNSQRISRGKSLETLTQDHSNTVRYRNAQREDSEIKMIQEKKEQAEMKRKVQEEELRENHPYFDKPLFIVGREHRFRNFCRVIVRARFNASKTDPVTGAVKNTKYHQLYDLLGLVTYLDWVMIVVTICSCISMMFESPFRRVMHTPTLQIAEYVFVIFMSIELNLKIMADGLFFTPTAVIRDFGGVMDIFIYLVSLIFLCWM--PNYVPAKSGTQLLMVLRCLRPLRIFKLVPQMRKVVRELFSGFKEIFLVSILLLTLMLVFASFGVQLFAGKLAKCNDPHILTREDCHGIFRINVSVSKNLNLKLKPEEKKPGFWVPRVWANPRNFNFDNVGNAMLALFEVLSLKGWVEVRDVIIHRVGPIHGIYIHVFVFLGCMIGLTLFVGVVIANFNENKGTALLTVDQRRWEDLKSRLKIAQPLHLPPRP-----------DNDGF------------RARMYDITQHPFFKRTIAVLVLAQSVLLSVKWDVEDPVTVP----LATMSVVFTFIFVLEVTMKITAMSPAGFWQSRRNRYDLLVTSLGVIWVILHFALLNEYTYMM-----GACIIVFRFFSICGKHVTLKMLLLTVVVSMYKSFFIIVGMFLLLLCYAFAGVVLFGTVKYGENINRHANFSTAGKAITVLFRIVTGEDWNKIMHDCMVQPPFCTPDNSKYWETDCGNYAGALMYFCSFYVIIAYIMLNLLVAIIVENFSLFYSTEEDQLLSPNDLRHYQIIWNMVDDKREGVIPAFRVKFLLRLLRGRLEVDLD----KDKLLFKHMCYEMERLHSGGD--VTFHDVLSMLSYRSVDIRKSLQLEELLAREQLEYTIEEEVAKQTIRMWLKKCLKRIRAKQ-------QQSCSIIHSLRESQQQEL--------------SRFLNPPSIETTQPSED---------------------MNLSNQDNAQPETSSQQQLLSPTLSDRGGYRQDSIEAGKPQRKFGQW-RLPAAPKPISHSVSSVNLRFGGRSTMKSVVCKMNAMSDAASCGSEVKKWWTRQLTVE 1733

[Close]

BLAST of Voltage-dependent calcium channel vs. Ensembl Xenopus
Match: NALCN (sodium leak channel, non selective [Source:NCBI gene;Acc:100492286])

HSP 1 Score: 1469.14 bits (3802), Expect = 0.000e+0
Identity = 861/1936 (44.47%), Postives = 1193/1936 (61.62%), Query Frame = 2

Query:  164 ERKTSHTRETQPTLPGVEFATDDA-GDLTSVNWVYTTWARCAFKIXXXXXXXXXXXNTPETFKEYKWLFYVTYLLDIVVALLFTAEMFTKMKIKGIIRPSPYVIVRHLFFVKVSNNIENKRPHAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIA--NSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWLVKNVFIAILTETFAEIRVQFQQMWSPKNQTDADSS-KIFQTDGQR-WKLVPVYESKPHGLAPKLFQEIVLKSTAFNVIIMLLVLANAIVAAGLHFNHDELT-QTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHCM--WYRTQLTYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEPKFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPNDWAQQLFSTFSGIYFILINLIFSFAFMSMFQILTQKGWVIVMHDTMDMAKHRGLNALVAIYFVFYHLFVTLIVLSLFVAVILDNLELEEDIKKLKQLKLREMSAETQQKLPMRLRIFEKFPNRPQMIKPARLLSDFLIPKIRDSFMRQFAQLPTLEEENESDEMIA------------AAVSGVGVSSLPRALSIEIKRQIRGLKGN---DKLNAIIYLINESNKTRMIE-----QPIIYPTRSLLSTQHQIRTERRNLRNRMAATTMSINQKPRLNGEIRNMDFETNRKTEEANHFDIKILQQKAEQAEIKRNQQVDDLRENHPYFDKPLFTIGRESQFRQLCRMLVEAQY---KPDINSENPEKQTFYKLQKFFGLVTYLDWVMIFVTTTSCISMAFETPTKRVMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTK-----LKLSGDSPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVGRINVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVDQRRWLDLKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTY-RENFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFIKAFYVRF-LLRLIPKDRVGFDFTKKKDQQLFKEMCYEVELLRGGKDKEVSFHDVLTMLAYRSVDISKTXXXXXXXXXXXXXXXXXXXXXRQTIATWIERCIFRNRQKHGDLKFGLRESNEMVIPIFDDKKEGLGLDRSRKISSGAYQTKFLSLPTLDGRQNTSDGSLPSSGITIGRLNDHLKNQPMGFKRRRSVKKNSSTNQTLTEVSEDELNDELNDIVPTQDPD-------LTPNQLP---------SLSDSHVPIENSISS-------RSEDK----HLTELVD-ADC-HEVKSWWHVQINTD 5770
            +RK S   E QP     +F  D++  D   + W+   W     +I A++S+ SV  NTP+TF+ Y  L YVT+ LD ++  L+TAEM  KM I+GI+                      K   +Y++  W  FD  MV CLW+S+ +Q FE+ K++   +P             +G+L   R PRPLI+ R  R + +F LP+TR+  IL RS  Q+++V++FLLFF+ LY ILGVQ FG     HCV       ++   +LAIPD+ C+P+   G  CP   +CV +        E GY+GF     S FTVY+AASQEGWVF+MYRA+D  P+W+   YFI++IFFLAWLVKNVFIA++ ETFAEIRVQFQQMW  ++ T + ++ ++F  D    W+LV V  +KP G AP   Q++ ++S+ F++ I+ +V  + IVAA  ++  +    Q + FY AE+ FT+LF++EA+ KIWCLG+  Y   SLHKFE +L +GTT+H     Y +Q TYFQVLR+ RL+K SP LEDF +KIFG GKKLG L++FT+ LLI+ S++SLQ+FC ++    + DR                                          F+TF              AFMSMFQILTQ+GWV VM  T++   H     +VAIYF+ YHLF TLI+LSLFVAVILDNLEL+ED+KKLKQLK  E +A+T++KLP+RLRIFEKFPNRPQM+K ++L SDF +PKIR+SFM+QF       ++ ++  ++             +  SGV  +   + +  ++++ +  ++     +K  A+  ++ +  + RM+      QP     RS+LS QH IR ERR+LR+   + +  I++   L    ++       +  +    +IK++Q+K EQAE+KR  Q ++LRENHPYFDKPLF +GRE +FR  CR++V A++   K D  +   +   +++L    GLVTYLDWVMI VT  SCISM FE+P +RVM+T  L++AEY+F + M+IE+ LK++A+G  FTP AV+RDFGGV+D FIY++ +IF+ +M   + + + SG Q+LM+LRCLRPLRIF LVP MR+VV EL  GF+EI +VS+LL+  M  FA +GV +F GKLA CNDP    ++DC G+F   +SV+K     LK     P F VPRVWANPRNFNFDN+GNAML LFEVLSL+GWVE+RDVI  RVG I+ IYIH+FVF+GC+IGLTLFVGVVIAN++ENKGTALLTVDQRRW DLK R+K+ QPLH+PPRP           DN+              R  +YD+TQH +FKR  A++VL   + L   W+ +D   +     LA+ +V +TFIF +E  +KITA+S  G+WQS+RN YD++VT L +IWV +H ++ + +   +     G   ++ RFFSI GKHVTLKML+ TV++SM+KS F+I+ MFLL+L YA AG++LFG+VKYGEN+ RHANF    ++I +LFRIVTGEDWNKIMHDCMVQPPFCT     +W++DCGN+  +L+YFCSFY++I YIMLN+LVAII+ENFSLFYS +ED ++S ND+R++Q  WN +D  R+G I AF V+F L  L  +  V  D    KD+ LFK MCYE+E L  G D  V+FHDVL+ML+YRSVDI K+LQLEELLARE+LEY IEEEVA+QTI  W+++C+ R R K        ++S  ++  + + +++ L              ++FL+ P+++  Q + D                     M    + + +  +S+ Q L   +  +      D +    P        L    LP         S   +  PI +S+SS       RS  K     +  + D A C  EVK WW  Q+  +
Sbjct:    3 KRKQSSRVEAQPV---TDFGPDESLSDNADILWINKPWVHSLLRICAIISVISVCMNTPKTFEHYPPLQYVTFALDTLLMFLYTAEMIAKMHIRGIV----------------------KGDTSYVKDRWCVFDGFMVFCLWVSLVLQVFEIAKIVDQMSP-------------WGML---RIPRPLIMIRAFRIYFRFELPRTRITNILKRSGEQIWSVSIFLLFFLLLYGILGVQMFGT-FTFHCVTNDTVHGNLTWNNLAIPDTHCSPE-GEGYQCPRGFRCVDLKELGLSRQELGYSGFNEIGTSIFTVYEAASQEGWVFLMYRAIDSFPRWRSYFYFITLIFFLAWLVKNVFIAVIIETFAEIRVQFQQMWGSRSSTTSTATTQMFHEDAAGGWQLVAVDVNKPQGRAPACLQKM-MRSSIFHMFILSMVAVDVIVAASNYYKGENFKRQYDEFYLAEVAFTMLFDLEALLKIWCLGFTGYISSSLHKFELLLVVGTTLHIYPDLYHSQFTYFQVLRVVRLIKISPALEDFVYKIFGPGKKLGSLVVFTASLLIVMSAISLQMFCFVE----ELDR------------------------------------------FTTFPR------------AFMSMFQILTQEGWVDVMDQTLNAVGHM-WAPVVAIYFILYHLFATLILLSLFVAVILDNLELDEDLKKLKQLKQSEANADTKEKLPLRLRIFEKFPNRPQMVKISKLPSDFTVPKIRESFMKQFID----RQQQDTSCLLRRLPSASSSSCDHSKRSGVEEN---KYIDQKLRKSVFSIRARNLLEKETAVNKILRDCTRQRMLSGSFEGQPA--KERSILSVQHHIRQERRSLRH--GSNSQRISRGKSLETLTQDHSNTVRYRNAQREDSEIKMIQEKKEQAEMKRKVQEEELRENHPYFDKPLFIVGREHRFRNFCRVIVRARFNASKTDPVTGAVKNTKYHQLYDLLGLVTYLDWVMIVVTICSCISMMFESPFRRVMHTPTLQIAEYVFVIFMSIELNLKIMADGLFFTPTAVIRDFGGVMDIFIYLVSLIFLCWM--PNYVPAKSGTQLLMVLRCLRPLRIFKLVPQMRKVVRELFSGFKEIFLVSILLLTLMLVFASFGVQLFAGKLAKCNDPHILTREDCHGIFRINVSVSKNLNLKLKPEEKKPGFWVPRVWANPRNFNFDNVGNAMLALFEVLSLKGWVEVRDVIIHRVGPIHGIYIHVFVFLGCMIGLTLFVGVVIANFNENKGTALLTVDQRRWEDLKSRLKIAQPLHLPPRP-----------DNDGF------------RARMYDITQHPFFKRTIAVLVLAQSVLLSVKWDVEDPVTVP----LATMSVVFTFIFVLEVTMKITAMSPAGFWQSRRNRYDLLVTSLGVIWVILHFALLNEYTYMM-----GACIIVFRFFSICGKHVTLKMLLLTVVVSMYKSFFIIVGMFLLLLCYAFAGVVLFGTVKYGENINRHANFSTAGKAITVLFRIVTGEDWNKIMHDCMVQPPFCTPDNSKYWETDCGNYAGALMYFCSFYVIIAYIMLNLLVAIIVENFSLFYSTEEDQLLSPNDLRHYQIIWNMVDDKREGVIPAFRVKFLLRLLRGRLEVDLD----KDKLLFKHMCYEMERLHSGGD--VTFHDVLSMLSYRSVDIRKSLQLEELLAREQLEYTIEEEVAKQTIRMWLKKCLKRIRAKQ-------QQSCSIIHSLRESQQQEL--------------SRFLNPPSIETTQPSED---------------------MNLSNQDNAQPETSSQQQLLSPTLSDRGGYRQDSIEAGKPQRKFGQWRLPRKALPMKAAVLNSASSKKAPKPISHSVSSVNLRFGGRSTMKSVVCKMNAMSDAASCGSEVKKWWTRQLTVE 1742

[Close]

BLAST of Voltage-dependent calcium channel vs. Ensembl Xenopus
Match: NALCN (sodium leak channel, non selective [Source:NCBI gene;Acc:100492286])

HSP 1 Score: 1444.48 bits (3738), Expect = 0.000e+0
Identity = 849/1920 (44.22%), Postives = 1176/1920 (61.25%), Query Frame = 2

Query:  164 ERKTSHTRETQPTLPGVEFATDDA-GDLTSVNWVYTTWARCAFKIXXXXXXXXXXXNTPETFKEYKWLFYVTYLLDIVVALLFTAEMFTKMKIKGIIRPSPYVIVRHLFFVKVSNNIENKRPHAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIA--NSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWLVKNVFIAILTETFAEIRVQFQQMWSPKNQTDADSS-KIFQTDGQR-WKLVPVYESKPHGLAPKLFQEIVLKSTAFNVIIMLLVLANAIVAAGLHFNHDELT-QTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHCM--WYRTQLTYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEPKFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPNDWAQQLFSTFSGIYFILINLIFSFAFMSMFQILTQKGWVIVMHDTMDMAKHRGLNALVAIYFVFYHLFVTLIVLSLFVAVILDNLELEEDIKKLKQLKLREMSAETQQKLPMRLRIFEKFPNRPQMIKPARLLSDFLIPKIRDSFMRQFAQLPTLEEENESDEMIA------------AAVSGVGVSSLPRALSIEIKRQIRGLKGN---DKLNAIIYLINESNKTRMIE-----QPIIYPTRSLLSTQHQIRTERRNLRNRMAATTMSINQKPRLNGEIRNMDFETNRKTEEANHFDIKILQQKAEQAEIKRNQQVDDLRENHPYFDKPLFTIGRESQFRQLCRMLVEAQY---KPDINSENPEKQTFYKLQKFFGLVTYLDWVMIFVTTTSCISMAFETPTKRVMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTK-----LKLSGDSPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVGRINVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVDQRRWLDLKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTY-RENFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFIKAFYVRF-LLRLIPKDRVGFDFTKKKDQQLFKEMCYEVELLRGGKDKEVSFHDVLTMLAYRSVDISKTXXXXXXXXXXXXXXXXXXXXXRQTIATWIERCIFRNRQKHGDLKFGLRESNEMVIPIFDDKKEGLGLDRSRKISSGAYQTKFLSLPTLDGRQNTSDGSLPSSGITIGRLNDHLKNQPMGFKRRRSVKKNSSTNQTLTEVSEDELNDELNDIVPTQDPDLTPNQLPSLSDSHVPIENSISS-------RSEDK----HLTELVD-ADC-HEVKSWWHVQINTD 5770
            +RK S   E QP     +F  D++  D   + W+   W     +I A++S+ SV  NTP+TF+ Y  L YVT+ LD ++  L+TAEM  KM I+GI+                      K   +Y++  W  FD  MV CLW+S+ +Q FE+ K++   +P             +G+L   R PRPLI+ R  R + +F LP+TR+  IL RS  Q+++V++FLLFF+ LY ILGVQ FG     HCV       ++   +LAIPD+ C+P+   G  CP   +CV +        E GY+GF     S FTVY+AASQEGWVF+MYRA+D  P+W+   YFI++IFFLAWLVKNVFIA++ ETFAEIRVQFQQMW  ++ T + ++ ++F  D    W+LV V  +KP G AP   Q++ ++S+ F++ I+ +V  + IVAA  ++  +    Q + FY AE+ FT+LF++EA+ KIWCLG+  Y   SLHKFE +L +GTT+H     Y +Q TYFQVLR+ RL+K SP LEDF +KIFG GKKLG L++FT+ LLI+ S++SLQ+FC ++    + DR                                          F+TF              AFMSMFQILTQ+GWV VM  T++   H     +VAIYF+ YHLF TLI+LSLFVAVILDNLEL+ED+KKLKQLK  E +A+T++KLP+RLRIFEKFPNRPQM+K ++L SDF +PKIR+SFM+QF       ++ ++  ++             +  SGV  +   + +  ++++ +  ++     +K  A+  ++ +  + RM+      QP     RS+LS QH IR ERR+LR+   + +  I++   L    ++       +  +    +IK++Q+K EQAE+KR  Q ++LRENHPYFDKPLF +GRE +FR  CR++V A++   K D  +   +   +++L    GLVTYLDWVMI VT  SCISM FE+P +RVM+T  L++AEY+F + M+IE+ LK++A+G  FTP AV+RDFGGV+D FIY++ +IF+ +M   + + + SG Q+LM+LRCLRPLRIF LVP MR+VV EL  GF+EI +VS+LL+  M  FA +GV +F GKLA CNDP    ++DC G+F   +SV+K     LK     P F VPRVWANPRNFNFDN+GNAML LFEVLSL+GWVE+RDVI  RVG I+ IYIH+FVF+GC+IGLTLFVGVVIAN++ENKGTALLTVDQRRW DLK R+K+ QPLH+PPRP           DN+              R  +YD+TQH +FKR  A++VL   + L                              ++  +KITA+S  G+WQS+RN YD++VT L +IWV +H ++ + +   +     G   ++ RFFSI GKHVTLKML+ TV++SM+KS F+I+ MFLL+L YA AG++LFG+VKYGEN+ RHANF    ++I +LFRIVTGEDWNKIMHDCMVQPPFCT     +W++DCGN+  +L+YFCSFY++I YIMLN+LVAII+ENFSLFYS +ED ++S ND+R++Q  WN +D  R+G I AF V+F L  L  +  V  D    KD+ LFK MCYE+E L  G D  V+FHDVL+ML+YRSVDI K+LQLEELLARE+LEY IEEEVA+QTI  W+++C+ R R K        ++S  ++  + + +++ L              ++FL+ P+++  Q + D                     M    + + +  +S+ Q L   +  +      D +    P     Q   L  +  PI +S+SS       RS  K     +  + D A C  EVK WW  Q+  +
Sbjct:    3 KRKQSSRVEAQPV---TDFGPDESLSDNADILWINKPWVHSLLRICAIISVISVCMNTPKTFEHYPPLQYVTFALDTLLMFLYTAEMIAKMHIRGIV----------------------KGDTSYVKDRWCVFDGFMVFCLWVSLVLQVFEIAKIVDQMSP-------------WGML---RIPRPLIMIRAFRIYFRFELPRTRITNILKRSGEQIWSVSIFLLFFLLLYGILGVQMFGT-FTFHCVTNDTVHGNLTWNNLAIPDTHCSPE-GEGYQCPRGFRCVDLKELGLSRQELGYSGFNEIGTSIFTVYEAASQEGWVFLMYRAIDSFPRWRSYFYFITLIFFLAWLVKNVFIAVIIETFAEIRVQFQQMWGSRSSTTSTATTQMFHEDAAGGWQLVAVDVNKPQGRAPACLQKM-MRSSIFHMFILSMVAVDVIVAASNYYKGENFKRQYDEFYLAEVAFTMLFDLEALLKIWCLGFTGYISSSLHKFELLLVVGTTLHIYPDLYHSQFTYFQVLRVVRLIKISPALEDFVYKIFGPGKKLGSLVVFTASLLIVMSAISLQMFCFVE----ELDR------------------------------------------FTTFPR------------AFMSMFQILTQEGWVDVMDQTLNAVGHM-WAPVVAIYFILYHLFATLILLSLFVAVILDNLELDEDLKKLKQLKQSEANADTKEKLPLRLRIFEKFPNRPQMVKISKLPSDFTVPKIRESFMKQFID----RQQQDTSCLLRRLPSASSSSCDHSKRSGVEEN---KYIDQKLRKSVFSIRARNLLEKETAVNKILRDCTRQRMLSGSFEGQPA--KERSILSVQHHIRQERRSLRH--GSNSQRISRGKSLETLTQDHSNTVRYRNAQREDSEIKMIQEKKEQAEMKRKVQEEELRENHPYFDKPLFIVGREHRFRNFCRVIVRARFNASKTDPVTGAVKNTKYHQLYDLLGLVTYLDWVMIVVTICSCISMMFESPFRRVMHTPTLQIAEYVFVIFMSIELNLKIMADGLFFTPTAVIRDFGGVMDIFIYLVSLIFLCWM--PNYVPAKSGTQLLMVLRCLRPLRIFKLVPQMRKVVRELFSGFKEIFLVSILLLTLMLVFASFGVQLFAGKLAKCNDPHILTREDCHGIFRINVSVSKNLNLKLKPEEKKPGFWVPRVWANPRNFNFDNVGNAMLALFEVLSLKGWVEVRDVIIHRVGPIHGIYIHVFVFLGCMIGLTLFVGVVIANFNENKGTALLTVDQRRWEDLKSRLKIAQPLHLPPRP-----------DNDGF------------RARMYDITQHPFFKRTIAVLVLAQSVLL-----------------------------SVKVTMKITAMSPAGFWQSRRNRYDLLVTSLGVIWVILHFALLNEYTYMM-----GACIIVFRFFSICGKHVTLKMLLLTVVVSMYKSFFIIVGMFLLLLCYAFAGVVLFGTVKYGENINRHANFSTAGKAITVLFRIVTGEDWNKIMHDCMVQPPFCTPDNSKYWETDCGNYAGALMYFCSFYVIIAYIMLNLLVAIIVENFSLFYSTEEDQLLSPNDLRHYQIIWNMVDDKREGVIPAFRVKFLLRLLRGRLEVDLD----KDKLLFKHMCYEMERLHSGGD--VTFHDVLSMLSYRSVDIRKSLQLEELLAREQLEYTIEEEVAKQTIRMWLKKCLKRIRAKQ-------QQSCSIIHSLRESQQQEL--------------SRFLNPPSIETTQPSED---------------------MNLSNQDNAQPETSSQQQLLSPTLSDRGGYRQDSIEAGKPQRKFGQW-RLPAAPKPISHSVSSVNLRFGGRSTMKSVVCKMNAMSDAASCGSEVKKWWTRQLTVE 1700

[Close]

BLAST of Voltage-dependent calcium channel vs. Ensembl Xenopus
Match: mrps11 (mitochondrial ribosomal protein S11 [Source:Xenbase;Acc:XB-GENE-970920])

HSP 1 Score: 201.445 bits (511), Expect = 5.855e-51
Identity = 294/1279 (22.99%), Postives = 543/1279 (42.46%), Query Frame = 2

Query: 1409 VLKSTAFNVIIMLLVLANAIVAAGLHFNHDELTQTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHCMW--YRTQLTY-------FQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEPKFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPNDWAQQLFSTFSGIYFILINLIFSFAFMSMFQILTQKGWVIVMHDTMDMAKHRGLNALVAIYFVFYHLFVTLIVLSLFVAVIL-----------DNLELEEDIKKLKQL-KLREMSA---------ETQQKLPMRLRIFEKFPNRP----QMIKPARLLSDFLIPKIRDSFM----RQFAQLPTLEEENESDEMIA-----AAVSGVGVSSLPRALSIEIKRQIR-GLKGNDKLNAII---YLINESNKTRMIEQPIIYPTRSLLSTQHQIRTERRNLRNRMAATTMSINQKPRLNGE---IRNMDFE------TNRKTEEANHFDIKILQQKAEQAEIKRNQQVDDLRENHPYFDKPLFTIGRESQFRQLCRMLVEAQYKPDINSENPEKQTFYKLQKFFGLVTYLDWVMIFVTTTSCISMAFETP--TKRVMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQI-----LMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVF-DRKISVTKLKLSGDSPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEI---------RDVIKARVGRINV-IYIHLFVFIGCLIGLTLFVGVVIANYSENKGTAL----LTVDQRRWLDLKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILA--SFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVL--LRFFSIAGKHVTLKMLMQTVLMSMFKSL-FVIIAMFLLMLVYALAGIILFGSVKYGEN--LGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCM----VQPPFCTYRENFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFIKAFYVRFLLRLI 4978
            ++KS  F  +++ +V  N    A +H N   L  +N  YYAE +F  LF +E  FK++ +G + Y++ S + F+  + +G+    +W  +R   ++        ++LRIF++ K    L +    +  S K +  L+      +++ + + +QL      Y  +F+     P A                                   F TF              A M++FQILT + W  VM++ +            +IYF+   LF    +L++F+A+ +           D  E EE   +   L K +E+S          E +++    L I+E+  ++     QM     L S+ L      S +    ++ A+  T +EE   D  +A         G G  S  R L    +++ R G   N + N       +    ++ R   + +    R   S  +     R    ++++A       + + NGE   ++ +D E      ++R  E++   D ++    ++Q + +   +  + R           TI R+ +  +  + +V        +S NP      K+  +   + Y +  ++ V   S I++A E P  T    N + L+  +Y+F    T EM +K++  G I    +  RD   +LDF + +  +I  A       + +  G+ I     L +LR LRPL+    +P ++ V   +V   + +  + ++  +FMF FAV  V +F GK   C D +K  +K+C+G + D + +  ++K           R W    +F++DNI  A+LTLF V + EGW ++          D   +R  R+ + I+  ++  +     + +FV ++I  + E     +    L  ++R  +D            I  +P  R    QNR                + R W + ++    F+     M+ +N + L   +     Y    +  LA    N+ +T +F +EC LKI A  F+ Y++   NI+D    F+++I     I + D+      S N  ++ +    R   +  +  T+++L+ T + S FK+L +V + + +L  +YA+ G+ +FG+++  E+  + RH NF + F S+ LLFR  TGE W +IM  C+     +P       +     CG  + + +YF SF    +++MLN+ VA+IM+NF   Y   + +I+  + +  F + W   D    G I    +  L+R+I
Sbjct:  473 MIKSQVFYWMVLGVVALNTFCVAIVHHNQT-LWLSNVLYYAEFLFLGLFLVEMAFKMYGMGPRLYFHSSFNCFDCGVTIGSIFEVLWAIFRPGTSFGISVLRALRLLRIFKITKYWASLRNLVVSLMNSMKSIISLLFLLFLFIVVFALLGMQL------YGGRFNFNDGTPSAN----------------------------------FDTFPA------------AIMTVFQILTGEDWNEVMYNGIRSQGGVRSGMWSSIYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKDEQEEEEAFNQKHALQKAKEVSPMSAPNASCIEKERRKRHTLSIWEQRTSQLRRHIQMSSQEALQSEELAALNPHSSIYRKTKEAAEQNTEKEEVHQDAKLAIDPVEGPPEGEGSPS-NRNLRENWRQKSRHGNSENTEPNGTTPEEAMRRRQSQRRSRHRRVRTEGREQCSNPNSTSASREGGLDKVSAEDGRTIPEEKSNGEAKEVKGVDDEPLKICISSRNCEDSEGRDGEVNFGSSQQEKEEEEAEDGEER-----------TIKRKEKLLESPKAIVPYSSMLIFSSTNP----IRKVCHYIVNLRYFEMSILLVIAASSIALAAEDPVLTNSDRNKV-LRYFDYVFTGVFTFEMIIKMIDQGLILHEGSYFRDLWNILDFVVVVGALIAFA-------LATNKGRDIKTIKSLRVLRVLRPLKTIKRLPKLKAVFDCVVNSLKNVFNILIVYKLFMFIFAVIAVQLFKGKFFYCTDSSKETEKECIGSYIDHEKNKMEVKR----------REWKR-HDFHYDNIIWALLTLFTVSTGEGWPQVLQHSVDITEEDRGPSRSNRMEMSIFYVIYFVVFPFFFVNIFVALIIITFQEQGDKMMEECSLEKNERACIDFA----------ISAKPLTRY-MPQNR-------------HTFQYRVWHFVVSPS--FEYTIMAMIALNTVVLMMKY-----YSAPYTYELALKYLNIAFTMLFSLECILKIIAFGFLNYFRDTWNIFD----FITVIGSITEIILTDSKLVNTSSFNMSFLKLFRAARLIKLLRQGYTIRILLWTFVQS-FKALPYVCLLIAMLFFIYAIIGMQVFGNIRLEEDSHINRHNNFRSFFSSLMLLFRSATGEAWQEIMLSCLSDKGCEPDTSAASGHNENERCGT-ELAYVYFVSFIFFCSFLMLNLFVAVIMDNFE--YLTRDSSILGPHHLDEFVRIWAEYDRAACGRIPYKDMYKLVRVI 1624

HSP 2 Score: 76.2554 bits (186), Expect = 6.299e-13
Identity = 132/655 (20.15%), Postives = 243/655 (37.10%), Query Frame = 2

Query:  386 DIVVALLFTAEMFTKMKIKGIIRPSPYVIVRHLFFVKVSNNIENKRPHAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILH---RSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANSIEDEGGYAGFGTFHF-----SFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYF--ISMIFFLAWLVKNVFIAILTETFAEIRVQFQQMWSPKNQTDADSSKIFQTDGQRWKLVPVYESKP---------HGLAPKLFQEIVLKSTAFNVIIMLLVLANAIVAAGLHFNHDELTQTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHCMWYRTQLT-----------YFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEP----KFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPNDWAQQLFSTFSGIYFILINLIFSFAFMSMFQILTQKGWVIVMHDTMDMAKHRGLNALVAIYFVFYHLFVTLIVLSLFVAVILDNLE 2248
            D V   +FT EM  KM  +G+I                          +Y R  W   D ++V+   I+  + T                        K   + T++S R L + R L++    RLP  ++KA+      S   V+N+ +    FM ++A++ VQ F      +C   S      K T+     S+ + +                 N +E +        FH+     +  T++  ++ EGW  ++  ++D   + +G S    + M  F            +    A I + FQ+      Q D    +      +R  +     +KP         H    +++  +V  S +F   IM ++  N +V   + +     T      Y  + FT+LF++E + KI   G+ +Y+  + + F+FI  +G+    +   ++L             F+  R+ +L++    +    +    S K L  + L  + L  I + + +Q+F +I++ E     + + F +F  + + +F   T E W E+M   + D    P+       S  SG                              H+       R    L  +YFV +  F + ++L+LFVAVI+DN E
Sbjct: 1047 DYVFTGVFTFEMIIKMIDQGLIL----------------------HEGSYFRDLWNILDFVVVVGALIAFALAT-----------------------NKGRDIKTIKSLRVLRVLRPLKTIK--RLP--KLKAVFDCVVNSLKNVFNILIVYKLFMFIFAVIAVQLFKGKF-FYCTDSS------KETEKECIGSYIDHE----------------KNKMEVKRREWKRHDFHYDNIIWALLTLFTVSTGEGWPQVLQHSVDITEEDRGPSRSNRMEMSIFYVIYFVVFPFFFVNIFVALIIITFQE------QGDKMMEECSLEKNERACIDFAISAKPLTRYMPQNRHTFQYRVWHFVV--SPSFEYTIMAMIALNTVVLM-MKYYSAPYTYELALKYLNIAFTMLFSLECILKIIAFGFLNYFRDTWNIFDFITVIGSITEIILTDSKLVNTSSFNMSFLKLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGNIRLEEDSHINRHNNFRSFFSSLMLLFRSATGEAWQEIMLSCLSDKGCEPDT------SAASG------------------------------HN----ENERCGTELAYVYFVSFIFFCSFLMLNLFVAVIMDNFE 1580

HSP 3 Score: 61.6178 bits (148), Expect = 1.786e-8
Identity = 57/254 (22.44%), Postives = 105/254 (41.34%), Query Frame = 2

Query:  530 AYLRHFWGCFDTIMVICLWISITIQTF------ELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWLVKNVFIAILTETFAEIRVQFQ 1273
            +YLR+ W   D I+V+   ++     F        L+ ++   PL              L+S + S     L  VL+S +K  +P              +  + + L F + ++AI+G++F+   ++  C     N S +++  +  P     P+      CP   +C +    I    G   F    F+  TV+Q  + EGW  ++Y   D L       YFI +I   ++ V N+ + +L+  FA+ R + +
Sbjct:  154 SYLRNGWNVMDFIVVLSGILATAGTHFNTHVDLRTLRAVRVLRPLK-------------LVSGIPS-----LQIVLKSIMKAMVP--------------LLQIGLLLFFAILMFAIIGLEFYSGKLHKACY---RNNSGMELDPMDPPHPCGVPR------CPAGYECKEW---IGPNDGITQFDNILFAVLTVFQCITMEGWTTVLYNTNDALGATWNWLYFIPLIIIGSFFVLNLVLGVLSGEFAKERERVE 363

[Close]

BLAST of Voltage-dependent calcium channel vs. Ensembl Xenopus
Match: mrps11 (mitochondrial ribosomal protein S11 [Source:Xenbase;Acc:XB-GENE-970920])

HSP 1 Score: 200.29 bits (508), Expect = 1.191e-50
Identity = 289/1260 (22.94%), Postives = 535/1260 (42.46%), Query Frame = 2

Query: 1409 VLKSTAFNVIIMLLVLANAIVAAGLHFNHDELTQTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHCMW--YRTQLTY-------FQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEPKFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPNDWAQQLFSTFSGIYFILINLIFSFAFMSMFQILTQKGWVIVMHDTMDMAKHRGLNALVAIYFVFYHLFVTLIVLSLFVAVIL-----------DNLELEEDIKKLKQL-KLREMSA---------ETQQKLPMRLRIFEKFPNRP----QMIKPARLLSDFLIPKIRDSFM----RQFAQLPTLEEENESDEMIA-----AAVSGVGVSSLPRALSIEIKRQIR-GLKGNDKLNAII---YLINESNKTRMIEQPIIYPTRSLLSTQHQIRTERRNLRNRMAATTMSINQKPRLNGE---IRNMDFE------TNRKTEEANHFDIKILQQKAEQAEIKRNQQVDDLRENHPYFDKPLFTIGRESQFRQLCRMLVEAQYKPDINSENPEKQTFYKLQKFFGLVTYLDWVMIFVTTTSCISMAFETP--TKRVMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQI-----LMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVF-DRKISVTKLKLSGDSPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEI---------RDVIKARVGRINV-IYIHLFVFIGCLIGLTLFVGVVIANYSENKGTAL----LTVDQRRWLDLKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILA--SFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVL--LRFFSIAGKHVTLKMLMQTVLMSMFKSL-FVIIAMFLLMLVYALAGIILFGSVKYGEN--LGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCM----VQPPFCTYRENFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSID 4921
            ++KS  F  +++ +V  N    A +H N   L  +N  YYAE +F  LF +E  FK++ +G + Y++ S + F+  + +G+    +W  +R   ++        ++LRIF++ K    L +    +  S K +  L+      +++ + + +QL      Y  +F+     P A                                   F TF              A M++FQILT + W  VM++ +            +IYF+   LF    +L++F+A+ +           D  E EE   +   L K +E+S          E +++    L I+E+  ++     QM     L S+ L      S +    ++ A+  T +EE   D  +A         G G  S  R L    +++ R G   N + N       +    ++ R   + +    R   S  +     R    ++++A       + + NGE   ++ +D E      ++R  E++   D ++    ++Q + +   +  + R           TI R+ +  +  + +V        +S NP      K+  +   + Y +  ++ V   S I++A E P  T    N + L+  +Y+F    T EM +K++  G I    +  RD   +LDF + +  +I  A       + +  G+ I     L +LR LRPL+    +P ++ V   +V   + +  + ++  +FMF FAV  V +F GK   C D +K  +K+C+G + D + +  ++K           R W    +F++DNI  A+LTLF V + EGW ++          D   +R  R+ + I+  ++  +     + +FV ++I  + E     +    L  ++R  +D            I  +P  R    QNR                + R W + ++    F+     M+ +N + L   +     Y    +  LA    N+ +T +F +EC LKI A  F+ Y++   NI+D    F+++I     I + D+      S N  ++ +    R   +  +  T+++L+ T + S FK+L +V + + +L  +YA+ G+ +FG+++  E+  + RH NF + F S+ LLFR  TGE W +IM  C+     +P       +     CG  + + +YF SF    +++MLN+ VA+IM+NF   Y   + +I+  + +  F + W   D
Sbjct:  473 MIKSQVFYWMVLGVVALNTFCVAIVHHNQT-LWLSNVLYYAEFLFLGLFLVEMAFKMYGMGPRLYFHSSFNCFDCGVTIGSIFEVLWAIFRPGTSFGISVLRALRLLRIFKITKYWASLRNLVVSLMNSMKSIISLLFLLFLFIVVFALLGMQL------YGGRFNFNDGTPSAN----------------------------------FDTFPA------------AIMTVFQILTGEDWNEVMYNGIRSQGGVRSGMWSSIYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKDEQEEEEAFNQKHALQKAKEVSPMSAPNASCIEKERRKRHTLSIWEQRTSQLRRHIQMSSQEALQSEELAALNPHSSIYRKTKEAAEQNTEKEEVHQDAKLAIDPVEGPPEGEGSPS-NRNLRENWRQKSRHGNSENTEPNGTTPEEAMRRRQSQRRSRHRRVRTEGREQCSNPNSTSASREGGLDKVSAEDGRTIPEEKSNGEAKEVKGVDDEPLKICISSRNCEDSEGRDGEVNFGSSQQEKEEEEAEDGEER-----------TIKRKEKLLESPKAIVPYSSMLIFSSTNP----IRKVCHYIVNLRYFEMSILLVIAASSIALAAEDPVLTNSDRNKV-LRYFDYVFTGVFTFEMIIKMIDQGLILHEGSYFRDLWNILDFVVVVGALIAFA-------LATNKGRDIKTIKSLRVLRVLRPLKTIKRLPKLKAVFDCVVNSLKNVFNILIVYKLFMFIFAVIAVQLFKGKFFYCTDSSKETEKECIGSYIDHEKNKMEVKR----------REWKR-HDFHYDNIIWALLTLFTVSTGEGWPQVLQHSVDITEEDRGPSRSNRMEMSIFYVIYFVVFPFFFVNIFVALIIITFQEQGDKMMEECSLEKNERACIDFA----------ISAKPLTRY-MPQNR-------------HTFQYRVWHFVVSPS--FEYTIMAMIALNTVVLMMKY-----YSAPYTYELALKYLNIAFTMLFSLECILKIIAFGFLNYFRDTWNIFD----FITVIGSITEIILTDSKLVNTSSFNMSFLKLFRAARLIKLLRQGYTIRILLWTFVQS-FKALPYVCLLIAMLFFIYAIIGMQVFGNIRLEEDSHINRHNNFRSFFSSLMLLFRSATGEAWQEIMLSCLSDKGCEPDTSAASGHNENERCGT-ELAYVYFVSFIFFCSFLMLNLFVAVIMDNFE--YLTRDSSILGPHHLDEFVRIWAEYD 1605

HSP 2 Score: 76.2554 bits (186), Expect = 6.219e-13
Identity = 132/655 (20.15%), Postives = 243/655 (37.10%), Query Frame = 2

Query:  386 DIVVALLFTAEMFTKMKIKGIIRPSPYVIVRHLFFVKVSNNIENKRPHAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILH---RSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANSIEDEGGYAGFGTFHF-----SFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYF--ISMIFFLAWLVKNVFIAILTETFAEIRVQFQQMWSPKNQTDADSSKIFQTDGQRWKLVPVYESKP---------HGLAPKLFQEIVLKSTAFNVIIMLLVLANAIVAAGLHFNHDELTQTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHCMWYRTQLT-----------YFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEP----KFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPNDWAQQLFSTFSGIYFILINLIFSFAFMSMFQILTQKGWVIVMHDTMDMAKHRGLNALVAIYFVFYHLFVTLIVLSLFVAVILDNLE 2248
            D V   +FT EM  KM  +G+I                          +Y R  W   D ++V+   I+  + T                        K   + T++S R L + R L++    RLP  ++KA+      S   V+N+ +    FM ++A++ VQ F      +C   S      K T+     S+ + +                 N +E +        FH+     +  T++  ++ EGW  ++  ++D   + +G S    + M  F            +    A I + FQ+      Q D    +      +R  +     +KP         H    +++  +V  S +F   IM ++  N +V   + +     T      Y  + FT+LF++E + KI   G+ +Y+  + + F+FI  +G+    +   ++L             F+  R+ +L++    +    +    S K L  + L  + L  I + + +Q+F +I++ E     + + F +F  + + +F   T E W E+M   + D    P+       S  SG                              H+       R    L  +YFV +  F + ++L+LFVAVI+DN E
Sbjct: 1047 DYVFTGVFTFEMIIKMIDQGLIL----------------------HEGSYFRDLWNILDFVVVVGALIAFALAT-----------------------NKGRDIKTIKSLRVLRVLRPLKTIK--RLP--KLKAVFDCVVNSLKNVFNILIVYKLFMFIFAVIAVQLFKGKF-FYCTDSS------KETEKECIGSYIDHE----------------KNKMEVKRREWKRHDFHYDNIIWALLTLFTVSTGEGWPQVLQHSVDITEEDRGPSRSNRMEMSIFYVIYFVVFPFFFVNIFVALIIITFQE------QGDKMMEECSLEKNERACIDFAISAKPLTRYMPQNRHTFQYRVWHFVV--SPSFEYTIMAMIALNTVVLM-MKYYSAPYTYELALKYLNIAFTMLFSLECILKIIAFGFLNYFRDTWNIFDFITVIGSITEIILTDSKLVNTSSFNMSFLKLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGNIRLEEDSHINRHNNFRSFFSSLMLLFRSATGEAWQEIMLSCLSDKGCEPDT------SAASG------------------------------HN----ENERCGTELAYVYFVSFIFFCSFLMLNLFVAVIMDNFE 1580

HSP 3 Score: 62.003 bits (149), Expect = 1.553e-8
Identity = 57/254 (22.44%), Postives = 105/254 (41.34%), Query Frame = 2

Query:  530 AYLRHFWGCFDTIMVICLWISITIQTF------ELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWLVKNVFIAILTETFAEIRVQFQ 1273
            +YLR+ W   D I+V+   ++     F        L+ ++   PL              L+S + S     L  VL+S +K  +P              +  + + L F + ++AI+G++F+   ++  C     N S +++  +  P     P+      CP   +C +    I    G   F    F+  TV+Q  + EGW  ++Y   D L       YFI +I   ++ V N+ + +L+  FA+ R + +
Sbjct:  154 SYLRNGWNVMDFIVVLSGILATAGTHFNTHVDLRTLRAVRVLRPLK-------------LVSGIPS-----LQIVLKSIMKAMVP--------------LLQIGLLLFFAILMFAIIGLEFYSGKLHKACY---RNNSGMELDPMDPPHPCGVPR------CPAGYECKEW---IGPNDGITQFDNILFAVLTVFQCITMEGWTTVLYNTNDALGATWNWLYFIPLIIIGSFFVLNLVLGVLSGEFAKERERVE 363

[Close]

BLAST of Voltage-dependent calcium channel vs. Ensembl Mouse
Match: Nalcn (sodium leak channel, non-selective [Source:MGI Symbol;Acc:MGI:2444306])

HSP 1 Score: 1486.86 bits (3848), Expect = 0.000e+0
Identity = 871/1923 (45.29%), Postives = 1187/1923 (61.73%), Query Frame = 2

Query:  164 ERKTSHTRETQPTLPGVEFATDDA-GDLTSVNWVYTTWARCAFKIXXXXXXXXXXXNTPETFKEYKWLFYVTYLLDIVVALLFTAEMFTKMKIKGIIRPSPYVIVRHLFFVKVSNNIENKRPHAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANS--IEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWLVKNVFIAILTETFAEIRVQFQQMWSPKNQTDADSS-KIFQTDGQR-WKLVPVYESKPHGLAPKLFQEIVLKSTAFNVIIMLLVLANAIVAAGLHFNHDELT-QTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHCM--WYRTQLTYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEPKFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPNDWAQQLFSTFSGIYFILINLIFSFAFMSMFQILTQKGWVIVMHDTMDMAKHRGLNALVAIYFVFYHLFVTLIVLSLFVAVILDNLELEEDIKKLKQLKLREMSAETQQKLPMRLRIFEKFPNRPQMIKPARLLSDFLIPKIRDSFMRQFAQLPTLEEENESDEMIAAAVSGVGVSSL--PRALSIEIKR-----------QIRGLKGNDKLNAIIYLINESNKTRMIE-----QPIIYPTRSLLSTQHQIRTERRNLRNRMAATTMSINQKPRLNGEIRNMDFETNRKTEEANHFDIKILQQKAEQAEIKRNQQVDDLRENHPYFDKPLFTIGRESQFRQLCRMLVEAQY---KPDINSENPEKQTFYKLQKFFGLVTYLDWVMIFVTTTSCISMAFETPTKRVMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTK-----LKLSGDSPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVGRINVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVDQRRWLDLKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRE-NFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFIKAFYVRF-LLRLIPKDRVGFDFTKKKDQQLFKEMCYEVELLRGGKDKEVSFHDVLTMLAYRSVDISKTXXXXXXXXXXXXXXXXXXXXXRQTIATWIERCIFRNR---QKHGDLKFGLRESNEMVIPIFDDKKEGLGLDRSRKISSGAYQTKFLSLPTLDGRQNTSDGSLPSSGITIGRLNDHLKNQPMGFKRRRSVKKNSSTNQTLTEVSEDELNDELNDIVPTQDPDLTPNQ--LPSLSDSHVPIENSISS-------RSEDK----HLTELVD-ADC-HEVKSWWHVQINTD 5770
            +RK S   E QP     +F  D++  D   + W+   W     +I A++S+ SV  NTP TF+ Y  L YVT+ LD ++  L+TAEM  KM I+GI+                      K   +Y++  W  FD  MV CLW+S+ +Q FE+  ++   +P             +G+L   R PRPLI+ R  R + +F LP+TR+  IL RS  Q+++V++FLLFF+ LY ILGVQ FG    +HCV+      ++    LAIPD+ C+P+ + G  CP   KC+ + +      E GY+GF     S FTVY+A+SQEGWVF+MYRA+D  P+W+   YFI++IFFLAWLVKNVFIA++ ETFAEIRVQFQQMW  ++ T + ++ ++F  D    W+LV V  +KP G AP   Q++ ++S+ F++ I+ +V  + IVAA  ++  +    Q + FY AE+ FT+LF++EA+ KIWCLG+  Y   SLHKFE +L +GTT+H     Y +Q TYFQVLR+ RL+K SP LEDF +KIFG GKKLG L++FT+ LLI+ S++SLQ+FC ++    + DR                                          F+TF              AFMSMFQILTQ+GWV VM  T++   H     LVAIYF+ YHLF TLI+LSLFVAVILDNLEL+ED+KKLKQLK  E +A+T++KLP+RLRIFEKFPNRPQM+K ++L SDF +PKIR+SFM+QF     ++ + +    +   +     SS   P+  + E  +            IR     +K  A+  ++    + RM+      QP     RS+LS QH IR ERR+LR+   + +  I++   L    ++       +  +    +IK++Q+K EQAE+KR  Q ++LRENHPYFDKPLF +GRE +FR  CR++V A++   K D  +   +   +++L    GLVTYLDWVMI VT  SCISM FE+P +RVM+   L++AEY+F + M+IE+ LK++A+G  FTP AV+RDFGGV+D FIY++ +IF+ +M +   + + SG Q+LM+LRCLRPLRIF LVP MR+VV EL  GF+EI +VS+LL+  M  FA +GV +F GKLA CNDP    ++DC G+F   +SV+K     L+     P F VPRVWANPRNFNFDN+GNAML LFEVLSL+GWVE+RDVI  RVG I+ IYIH+FVF+GC+IGLTLFVGVVIAN++ENKGTALLTVDQRRW DLK R+K+ QPLH+PPRP           DN+              R  +YD+TQH +FKR  A++VL   + L   W+ DD   +     LA+ +V +TFIF +E  +KI A+S  G+WQS+RN YD++VT L ++WV +H ++ + +   +     G   ++ RFFSI GKHVTLKML+ TV++SM+KS F+I+ MFLL+L YA AG++LFG+VKYGEN+ RHANF +  ++I +LFRIVTGEDWNKIMHDCMVQPPFCT  E  +W +DCGN+  +L+YFCSFY++I YIMLN+LVAII+ENFSLFYS +ED ++SYND+R+FQ  WN +D  R+G I  F V+F L  L  +  V  D    KD+ LFK MCYE+E L  G D  V+FHDVL+ML+YRSVDI K+LQLEELLARE+LEY IEEEVA+QTI  W+++C+ R R   Q+   +   LRES E               +RSR          FL+ P+++  Q + D +  S         DH            S++  +S+ Q L   +  +      D   T  P     Q  LPS      PI +S+SS       R+  K     +  + D A C  EVK WW  Q+  +
Sbjct:    3 KRKQSSRVEAQPV---TDFGPDESLSDNADILWINKPWVHSLLRICAIISVISVCMNTPMTFEHYPPLQYVTFTLDTLLMFLYTAEMIAKMHIRGIV----------------------KGDSSYVKDRWCVFDGFMVFCLWVSLVLQVFEIADIVDQMSP-------------WGML---RIPRPLIMIRAFRIYFRFELPRTRITNILKRSGEQIWSVSIFLLFFLLLYGILGVQMFGT-FTYHCVVNDTKPGNVTWNSLAIPDTHCSPELEEGYQCPPGFKCMDLEDLGLSRQELGYSGFNEIGTSIFTVYEASSQEGWVFLMYRAIDSFPRWRSYFYFITLIFFLAWLVKNVFIAVIIETFAEIRVQFQQMWGTRSSTTSTATTQMFHEDAAGGWQLVAVDVNKPQGRAPACLQKM-MRSSVFHMFILSMVTVDVIVAASNYYKGENFRRQYDEFYLAEVAFTVLFDLEALLKIWCLGFTGYISSSLHKFELLLVIGTTLHVYPDLYHSQFTYFQVLRVVRLIKISPALEDFVYKIFGPGKKLGSLVVFTASLLIVMSAISLQMFCFVE----ELDR------------------------------------------FTTFPR------------AFMSMFQILTQEGWVDVMDQTLNAVGHM-WAPLVAIYFILYHLFATLILLSLFVAVILDNLELDEDLKKLKQLKQSEANADTKEKLPLRLRIFEKFPNRPQMVKISKLPSDFTVPKIRESFMKQF-----IDRQQQDTCCLFRILPSTSSSSCDNPKKPTAEDNKYIDQKLRKSVFSIRARNLLEKETAVTKILRACTRQRMLSGSFEGQPA--KERSILSVQHHIRQERRSLRH--GSNSQRISRGKSLETLTQDHSNTVRYRNAQREDSEIKMIQEKKEQAEMKRKVQEEELRENHPYFDKPLFIVGREHRFRNFCRVVVRARFNASKTDPVTGAVKNTKYHQLYDLLGLVTYLDWVMITVTICSCISMMFESPFRRVMHAPTLQIAEYVFVIFMSIELNLKIMADGLFFTPTAVIRDFGGVMDIFIYLVSLIFLCWMPQ--NVPAESGAQLLMVLRCLRPLRIFKLVPQMRKVVRELFSGFKEIFLVSILLLTLMLVFASFGVQLFAGKLAKCNDPNIIRREDCNGIFRINVSVSKNLNLKLRPGEKKPGFWVPRVWANPRNFNFDNVGNAMLALFEVLSLKGWVEVRDVIIHRVGPIHGIYIHVFVFLGCMIGLTLFVGVVIANFNENKGTALLTVDQRRWEDLKSRLKIAQPLHLPPRP-----------DNDGF------------RAKMYDITQHPFFKRTIALLVLAQSVLLSVKWDVDDPVTVP----LATMSVVFTFIFVLEVTMKIIAMSPAGFWQSRRNRYDLLVTSLGVVWVVLHFALLNAYTYMM-----GACVIVFRFFSICGKHVTLKMLLLTVVVSMYKSFFIIVGMFLLLLCYAFAGVVLFGTVKYGENINRHANFSSAGKAITVLFRIVTGEDWNKIMHDCMVQPPFCTPDEFTYWATDCGNYAGALMYFCSFYVIIAYIMLNLLVAIIVENFSLFYSTEEDQLLSYNDLRHFQIIWNMVDDKREGVIPTFRVKFLLRLLRGRLEVDLD----KDKLLFKHMCYEMERLHNGGD--VTFHDVLSMLSYRSVDIRKSLQLEELLAREQLEYTIEEEVAKQTIRMWLKKCLKRIRAKQQQSCSIIHSLRESQEQ--------------ERSR---------LFLNPPSIETTQPSEDSNANS--------QDH------------SMQPETSSQQQLLSPTLSDRGGSRQDAADTGKPQRKIGQWRLPSAPK---PISHSVSSVNLRFGGRTTMKTVVCKMNPMPDTASCGSEVKKWWTRQLTVE 1728

[Close]

BLAST of Voltage-dependent calcium channel vs. Ensembl Mouse
Match: Cacna1s (calcium channel, voltage-dependent, L type, alpha 1S subunit [Source:MGI Symbol;Acc:MGI:88294])

HSP 1 Score: 184.882 bits (468), Expect = 3.625e-46
Identity = 202/810 (24.94%), Postives = 357/810 (44.07%), Query Frame = 2

Query: 2711 NRMAATTMSINQKPRLNG-EIRNMDFETNRKTEEANHFDIKILQQKAE------QAEIKRNQ---QVDDLRENHPYFDKPLFTIGRESQF--RQLCRMLVEAQYK------PDINSE---NPEKQTFYKLQKFFGLVTYLDWVMIFVTTTSCISMAFETPTKR-VMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTKLKLSGDSPSF-LVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEI---------RDVIKARVGRINVIYIHLFVFIGCLIGL-TLFVGVVIANYSENKGTAL----LTVDQRRWLD--LKGRIKLTQPL--HIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKY--GENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRENFWQSD---CG-NFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFIKAFYVRFLLRLIPKDRVGF 4999
            N   A +++  QK +    + R M      K+EE      K L+QK++       A++K ++    V+++++ +P  D P      E +       R L E Q K      P+ +S    +P  +      +      + +++++F+  +S  ++A E P +   M    L+  +Y+F    T+E+ LK+   G      +  R++  +LD  +  + +I +       ++      +IL +LR LRPLR       ++ VV  +    R I  + ++  +  F FA  GV +F GK   CND +K  +++C G +        +   GD     L PR W +  +F+FDN+ +AM++LF V + EGW ++          D       R+ +    +   I     +  +FVG VI  + E   T      L  +QR+ +   LK R     PL  +IP  P   Q                           V+ +    YF+ +   ++++N I L     N  E     S IL   NV +T IF +E  LK+ A    GY+    N++D ++   S+I V +   + D   S  +S+ F  +  ++R   +  +   ++ L+ T + S     +V + + +L  +YA+ G+ +FG +    G  + R+ NF    +++ LLFR  TGE W +I+  C      C    ++   +   CG NF  +  YF SFY++  ++++N+ VA+IM+NF   Y   + +I+  + +  F+  W   D   KG IK   V  LLR I +  +GF
Sbjct:  416 NLAEAESLTSAQKAKAEERKRRKMSKGLPDKSEEERATVTKKLEQKSKGEGIPTTAKLKIDEFESNVNEVKDPYPSADFPGDDEEDEPEIPVSPRPRPLAELQLKEKAVPIPEASSFFIFSPTNKIRVLCHRIVNATWFTNFILLFILLSSA-ALAAEDPIRADSMRNQILEYFDYVFTAVFTVEIVLKMTTYGAFLHKGSFCRNYFNILDLLVVAVSLISMGLESSAISV-----VKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVLVTTLLQFMFACIGVQLFKGKFYSCNDLSKMTEEECRGYY-------YIYKDGDPTQIELRPRQWIH-NDFHFDNVLSAMMSLFTVSTFEGWPQLLYKAIDSNEEDTGPVYNNRVEMAIFFIIYIILIAFFMMNIFVGFVIVTFQEQGETEYKNCELDKNQRQCVQYALKAR-----PLRCYIPKNPYQYQ---------------------------VWYVVTSSYFEYLMFALIMLNTICLGMQHYNQSEQMNHISDIL---NVAFTIIFTLEMVLKLIAFKPRGYFGDPWNVFDFLIVIGSIIDVILS-EIDDPDESARISSAFFRLFRVMRLVKLLNRAEGVRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMFGKIAMVDGTQINRNNNFQTFPQAVLLLFRCATGEAWQEILLACSYG-KLCDPESDYAPGEEHTCGTNF--AYYYFISFYMLCAFLIINLFVAVIMDNFD--YLTRDWSILGPHHLDEFKAIWAEYDPEAKGRIKHLDVVTLLRRI-QPPLGF 1169

HSP 2 Score: 80.8777 bits (198), Expect = 1.909e-14
Identity = 95/418 (22.73%), Postives = 190/418 (45.45%), Query Frame = 2

Query: 3662 WANPRN--FNFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVG-RINVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTAL-------LTVDQRRWLDLKGRIKLTQPLHIPPRPKMRQDS---TQNRTDNNAINENSFDNRVIK-VRCW----------VYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGS-VKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRENFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFS 4840
            W  P +   +FDN G +MLT+++ +S+EGW ++   +   +G     IY    + +G    L L +GV+   +++ +  A        L   Q+   DL+G +       +     +R+      +  +D  ++ E    N++I+ +R W           +DL +   F  +  ++V +N + +    +N   +      +     +T   +F IE  +K+  L    Y+ S  N +D  V    ++ + +   V+    S +  +    +  LLR F I     +L  L+ ++L S+     +++ +FL ++++AL G+ LFG    + +   R +NF N  +++  +F+++TGEDWN +M++ ++     TY                IYF   ++   YI+LNV +AI ++N +
Sbjct:   18 WPGPNHGITHFDNFGFSMLTVYQCISMEGWTDVLYWVNDAIGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKQQLEEDLRGYMSWITQGEVMDVDDLREGKLSLDEGGSDTESLYEIEGLNKIIQFIRHWRQWNRVFRWKCHDLVKSKVFYWLVILIVALNTLSIASEHHNQPLWLTHLQDVANRVLLT---LFTIEMLMKMYGLGLRQYFMSIFNRFDCFVVCSGILEILL---VESGAMSPLGISVLRCIR-LLRLFKITKYWTSLSNLVASLLNSIRSIASLLLLLFLFIIIFALLGMQLFGGRYDFEDTEVRRSNFDNFPQALISVFQVLTGEDWNSVMYNGIMAYGGPTYPGVL----------VCIYFIILFVCGNYILLNVFLAIAVDNLA 418

HSP 3 Score: 80.4925 bits (197), Expect = 2.318e-14
Identity = 135/614 (21.99%), Postives = 250/614 (40.72%), Query Frame = 2

Query: 1028 NSIEDEGGYAG-------FGTFHFSFFTVYQAASQEGWVFIMYRAMDCLP-QWKGVSYFISMIFFLAWLVKNVFIAILTETF------AEIRVQFQQMWSPKNQTDAD---------SSKIFQTDGQRWKLVPVYESKP--------HGLAPKLFQEI----------------VLKSTAFNVIIMLLVLANAIVAAGLHFNHDELTQTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFE-FILCLG--------TTVHCMWYRTQLTYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCS---IQIYEPKFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPNDWAQQLFSTFSGIYFILINLIFSFAFMSMFQILTQKGWVIVMHDTMDMAKHRGLNALVAIYFVFYHLFVTLIVLSLFVAVILDNLELEEDI-----KKLKQLKLREMSA----ETQQKLPMRLRIFEKFPNRPQMIKPARLLSDFL---IPKIRDSFMRQFAQLPTLEEENESDEMIAAAVSGVGVSSLPRALSIEIKRQIRGLKGNDKLNAIIYLINESNKTRMIEQPIIYPT 2656
            N  E  GG+ G       F  F FS  TVYQ  S EGW  ++Y   D +  +W  + YF+++I   ++ + N+ + +L+  F      A+ R  FQ++   K Q + D           ++   D  R   + + E            GL  K+ Q I                ++KS  F  +++L+V  N +  A  H N   L  T+    A  V   LF IE + K++ LG + Y+    ++F+ F++C G        +        + L   ++LR+F++ K    L +    +  S + +  L+L     +II + + +QLF      +  E +   F NFP+A + +F ++T E W  VM   ++ A   P         T+ G+                                           LV IYF+   +    I+L++F+A+ +DNL   E +      K ++ K R+MS     +++++     +  E+      +   A+L  D     + +++D +    A  P  +EE+E +         + VS  PR L+ E++ + + +   +   +  ++ + +NK R++   I+  T
Sbjct:   10 NGSECRGGWPGPNHGITHFDNFGFSMLTVYQCISMEGWTDVLYWVNDAIGNEWPWI-YFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKL-REKQQLEEDLRGYMSWITQGEVMDVDDLREGKLSLDEGGSDTESLYEIEGLN-KIIQFIRHWRQWNRVFRWKCHDLVKSKVFYWLVILIVALNTLSIASEHHNQP-LWLTHLQDVANRVLLTLFTIEMLMKMYGLGLRQYFMSIFNRFDCFVVCSGILEILLVESGAMSPLGISVLRCIRLLRLFKITKYWTSLSNLVASLLNSIRSIASLLLLLFLFIIIFALLGMQLFGGRYDFEDTEVRRSNFDNFPQALISVFQVLTGEDWNSVMYNGIM-AYGGP---------TYPGV-------------------------------------------LVCIYFIILFVCGNYILLNVFLAIAVDNLAEAESLTSAQKAKAEERKRRKMSKGLPDKSEEERATVTKKLEQKSKGEGIPTTAKLKIDEFESNVNEVKDPYPS--ADFPGDDEEDEPE---------IPVSPRPRPLA-ELQLKEKAVPIPEA--SSFFIFSPTNKIRVLCHRIVNAT 552

HSP 4 Score: 64.3142 bits (155), Expect = 2.164e-9
Identity = 88/406 (21.67%), Postives = 170/406 (41.87%), Query Frame = 2

Query: 1070 FHF-----SFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSY---------FISMIFFLAWLVKNVFIAILTETFAEI-RVQFQQMWSPKNQTDADSSKIFQTDGQRWKLVPVYESKPHGLAPKLFQE-IVLKSTAFNVIIMLLVLANAIVAAGLHFNHDELTQTNGFY-YAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHCMW---------YRTQLTYFQVLRIFRLMK---ASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEP----KFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIP-NDWA----QQLFSTFSGIYFILINLIFSFAFMSMFQILTQKGWVIVMHDTMDMAKHRGLNALVAIY 2173
            FHF     +  +++  ++ EGW  ++Y+A+D   +  G  Y         FI  I  +A+ + N+F+  +  TF E    +++     KNQ       +        K  P+    P    P  +Q   V+ S+ F  ++  L++ N I     H+N  E  Q N       + FTI+F +E V K+     + Y+    + F+F++ +G+ +  +           R    +F++ R+ RL+K    +  +    +    S + L  + L    L  I + + +Q+F  I + +     + + F  FP+A L +F   T E W E++          P +D+A        + F+  YFI   ++ +F  +++F  +    +  +  D   +  H  L+   AI+
Sbjct:  748 FHFDNVLSAMMSLFTVSTFEGWPQLLYKAIDSNEEDTGPVYNNRVEMAIFFIIYIILIAFFMMNIFVGFVIVTFQEQGETEYKNCELDKNQRQCVQYAL--------KARPLRCYIPKN--PYQYQVWYVVTSSYFEYLMFALIMLNTICLGMQHYNQSE--QMNHISDILNVAFTIIFTLEMVLKLIAFKPRGYFGDPWNVFDFLIVIGSIIDVILSEIDDPDESARISSAFFRLFRVMRLVKLLNRAEGVRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMFGKIAMVDGTQINRNNNFQTFPQAVLLLFRCATGEAWQEILLACSYGKLCDPESDYAPGEEHTCGTNFAYYYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHH-LDEFKAIW 1140

[Close]

BLAST of Voltage-dependent calcium channel vs. Ensembl Mouse
Match: Cacna1s (calcium channel, voltage-dependent, L type, alpha 1S subunit [Source:MGI Symbol;Acc:MGI:88294])

HSP 1 Score: 184.496 bits (467), Expect = 5.491e-46
Identity = 202/811 (24.91%), Postives = 356/811 (43.90%), Query Frame = 2

Query: 2711 NRMAATTMSINQKPRLNG-EIRNMDFETNRKTEEANHFDIKILQQKAE------QAEIKRNQ---QVDDLRENHPYFDKPLFTIGRESQF--RQLCRMLVEAQYKPDINSENPEKQTFYKL----------QKFFGLVTYLDWVMIFVTTTSCISMAFETPTKR-VMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTKLKLSGDSPSF-LVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEI---------RDVIKARVGRINVIYIHLFVFIGCLIGL-TLFVGVVIANYSENKGTAL----LTVDQRRWLD--LKGRIKLTQPL--HIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKY--GENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRENFWQSD---CG-NFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFIKAFYVRFLLRLIPKDRVGF 4999
            N   A +++  QK +    + R M      K+EE      K L+QK++       A++K ++    V+++++ +P  D P      E +       R L E Q K +     PE  +F+             +      + +++++F+  +S  ++A E P +   M    L+  +Y+F    T+E+ LK+   G      +  R++  +LD  +  + +I +       ++      +IL +LR LRPLR       ++ VV  +    R I  + ++  +  F FA  GV +F GK   CND +K  +++C G +        +   GD     L PR W +  +F+FDN+ +AM++LF V + EGW ++          D       R+ +    +   I     +  +FVG VI  + E   T      L  +QR+ +   LK R     PL  +IP  P   Q                           V+ +    YF+ +   ++++N I L     N  E     S IL   NV +T IF +E  LK+ A    GY+    N++D ++   S+I V +   + D   S  +S+ F  +  ++R   +  +   ++ L+ T + S     +V + + +L  +YA+ G+ +FG +    G  + R+ NF    +++ LLFR  TGE W +I+  C      C    ++   +   CG NF  +  YF SFY++  ++++N+ VA+IM+NF   Y   + +I+  + +  F+  W   D   KG IK   V  LLR I +  +GF
Sbjct:  663 NLAEAESLTSAQKAKAEERKRRKMSKGLPDKSEEERATVTKKLEQKSKGEGIPTTAKLKIDEFESNVNEVKDPYPSADFPGDDEEDEPEIPVSPRPRPLAELQLK-EKAVPIPEASSFFIFSPTNKIRVLCHRIVNATWFTNFILLFILLSSA-ALAAEDPIRADSMRNQILEYFDYVFTAVFTVEIVLKMTTYGAFLHKGSFCRNYFNILDLLVVAVSLISMGLESSAISV-----VKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVLVTTLLQFMFACIGVQLFKGKFYSCNDLSKMTEEECRGYY-------YIYKDGDPTQIELRPRQWIH-NDFHFDNVLSAMMSLFTVSTFEGWPQLLYKAIDSNEEDTGPVYNNRVEMAIFFIIYIILIAFFMMNIFVGFVIVTFQEQGETEYKNCELDKNQRQCVQYALKAR-----PLRCYIPKNPYQYQ---------------------------VWYVVTSSYFEYLMFALIMLNTICLGMQHYNQSEQMNHISDIL---NVAFTIIFTLEMVLKLIAFKPRGYFGDPWNVFDFLIVIGSIIDVILS-EIDDPDESARISSAFFRLFRVMRLVKLLNRAEGVRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMFGKIAMVDGTQINRNNNFQTFPQAVLLLFRCATGEAWQEILLACSYG-KLCDPESDYAPGEEHTCGTNF--AYYYFISFYMLCAFLIINLFVAVIMDNFD--YLTRDWSILGPHHLDEFKAIWAEYDPEAKGRIKHLDVVTLLRRI-QPPLGF 1416

HSP 2 Score: 128.257 bits (321), Expect = 7.578e-29
Identity = 158/713 (22.16%), Postives = 313/713 (43.90%), Query Frame = 2

Query: 2834 LQQKAEQAE-IKRNQQVDDLRENHPYFDKPLFTIGRESQFRQLCRMLVEAQYKPDINSENPEKQTFYKLQKFFGLVTYLDWVMIFVTTTSCISMAFETPTKRVMNT---IELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTI----------GSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLA-----ICNDPTKTEKKDCVGVFDRKISVTKLKLSGDSPSFLVPRVWANPRN--FNFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVG-RINVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTA-------LLTVDQRRWLDLKGRIKLTQPLHIPPRPKMRQDS---TQNRTDNNAINENSFDNRVIK-VRCW----------VYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGS-VKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRENFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFS 4840
            ++  + Q E +++ Q    + E  P   + LF +  ++  R+ C  +VE  +KP                         + +++     +C+++A   P     N    + L+  EY F +  +IE A+K++A GF+F   A +R    VLDF I  +  +F   + +V+ I          G+G   + L   R LRPLR+   VP ++ V+  + +    +  +++L++  +  +A+ G+ +F GK+      I  D   T + +      R  S     ++G          W  P +   +FDN G +MLT+++ +S+EGW ++   +   +G     IY    + +G    L L +GV+   +++ +  A        L   Q+   DL+G +       +     +R+      +  +D  ++ E    N++I+ +R W           +DL +   F  +  ++V +N + +    +N   +      +     +T   +F IE  +K+  L    Y+ S  N +D  V    ++ + +   V+    S +  +    +  LLR F I     +L  L+ ++L S+     +++ +FL ++++AL G+ LFG    + +   R +NF N  +++  +F+++TGEDWN +M++ ++     TY                IYF   ++   YI+LNV +AI ++N +
Sbjct:    1 MEPPSPQDEGLRKKQPKKPVPEILPRPPRALFCLTLQNPLRKACISIVE--WKP------------------------FETIILLTIFANCVALAVYLPMPEDDNNTLNLGLEKLEYFFLIVFSIEAAMKIIAYGFLFHQDAYLRSGWNVLDFIIVFLG-VFTVILEQVNIIQTNTAPMSSKGAGLDVKALRAFRVLRPLRLVSGVPSLQVVLNSIFKAMLPLFHIALLVLFMVIIYAIIGLELFKGKMHKTCYFIGTDIVATVENEKPSPCARTGSGRPCTINGSE----CRGGWPGPNHGITHFDNFGFSMLTVYQCISMEGWTDVLYWVNDAIGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKQQLEEDLRGYMSWITQGEVMDVDDLREGKLSLDEGGSDTESLYEIEGLNKIIQFIRHWRQWNRVFRWKCHDLVKSKVFYWLVILIVALNTLSIASEHHNQPLWLTHLQDVANRVLLT---LFTIEMLMKMYGLGLRQYFMSIFNRFDCFVVCSGILEILL---VESGAMSPLGISVLRCIR-LLRLFKITKYWTSLSNLVASLLNSIRSIASLLLLLFLFIIIFALLGMQLFGGRYDFEDTEVRRSNFDNFPQALISVFQVLTGEDWNSVMYNGIMAYGGPTYPGVL----------VCIYFIILFVCGNYILLNVFLAIAVDNLA 665

HSP 3 Score: 100.908 bits (250), Expect = 1.735e-20
Identity = 176/792 (22.22%), Postives = 321/792 (40.53%), Query Frame = 2

Query:  530 AYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCET-PLDSCKELITFWQKYGL----LSTLRSPRPLILTR-------VLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANSIEDEGGYAG-------FGTFHFSFFTVYQAASQEGWVFIMYRAMDCLP-QWKGVSYFISMIFFLAWLVKNVFIAILTETF------AEIRVQFQQMWSPKNQTDAD---------SSKIFQTDGQRWKLVPVYESKP--------HGLAPKLFQEI----------------VLKSTAFNVIIMLLVLANAIVAAGLHFNHDELTQTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFE-FILCLG--------TTVHCMWYRTQLTYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCS---IQIYEPKFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPNDWAQQLFSTFSGIYFILINLIFSFAFMSMFQILTQKGWVIVMHDTMDMAKHRGLNALVAIYFVFYHLFVTLIVLSLFVAVILDNLELEEDI-----KKLKQLKLREMSA----ETQQKLPMRLRIFEKFPNRPQMIKPARLLSDFL---IPKIRDSFMRQFAQLPTLEEENESDEMIAAAVSGVGVSSLPRALSIEIKRQIRGLKGNDKLNAIIYLINESNKTRMIEQPIIYPT 2656
            AYLR  W   D I+V   ++ +     E + +I+  T P+ S        +  GL    L   R  RPL L         VL S  K  LP              ++++ + +LF + +YAI+G++ F   ++  C       +DI  T   + +   +P  ++G   P ++      N  E  GG+ G       F  F FS  TVYQ  S EGW  ++Y   D +  +W  + YF+++I   ++ + N+ + +L+  F      A+ R  FQ++   K Q + D           ++   D  R   + + E            GL  K+ Q I                ++KS  F  +++L+V  N +  A  H N   L  T+    A  V   LF IE + K++ LG + Y+    ++F+ F++C G        +        + L   ++LR+F++ K    L +    +  S + +  L+L     +II + + +QLF      +  E +   F NFP+A + +F ++T E W  VM   ++ A   P         T+ G+                                           LV IYF+   +    I+L++F+A+ +DNL   E +      K ++ K R+MS     +++++     +  E+      +   A+L  D     + +++D +    A  P  +EE+E +         + VS  PR L+ E++ + + +   +   +  ++ + +NK R++   I+  T
Sbjct:  116 AYLRSGWNVLDFIIV---FLGVFTVILEQVNIIQTNTAPMSS--------KGAGLDVKALRAFRVLRPLRLVSGVPSLQVVLNSIFKAMLP--------------LFHIALLVLFMVIIYAIIGLELFKGKMHKTCYFIG---TDIVAT---VENEKPSPCARTGSGRPCTI------NGSECRGGWPGPNHGITHFDNFGFSMLTVYQCISMEGWTDVLYWVNDAIGNEWPWI-YFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKL-REKQQLEEDLRGYMSWITQGEVMDVDDLREGKLSLDEGGSDTESLYEIEGLN-KIIQFIRHWRQWNRVFRWKCHDLVKSKVFYWLVILIVALNTLSIASEHHNQ-PLWLTHLQDVANRVLLTLFTIEMLMKMYGLGLRQYFMSIFNRFDCFVVCSGILEILLVESGAMSPLGISVLRCIRLLRLFKITKYWTSLSNLVASLLNSIRSIASLLLLLFLFIIIFALLGMQLFGGRYDFEDTEVRRSNFDNFPQALISVFQVLTGEDWNSVMYNGIM-AYGGP---------TYPGV-------------------------------------------LVCIYFIILFVCGNYILLNVFLAIAVDNLAEAESLTSAQKAKAEERKRRKMSKGLPDKSEEERATVTKKLEQKSKGEGIPTTAKLKIDEFESNVNEVKDPYPS--ADFPGDDEEDEPE---------IPVSPRPRPLA-ELQLKEKAVPIPEA--SSFFIFSPTNKIRVLCHRIVNAT 799

HSP 4 Score: 64.3142 bits (155), Expect = 2.283e-9
Identity = 88/406 (21.67%), Postives = 170/406 (41.87%), Query Frame = 2

Query: 1070 FHF-----SFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSY---------FISMIFFLAWLVKNVFIAILTETFAEI-RVQFQQMWSPKNQTDADSSKIFQTDGQRWKLVPVYESKPHGLAPKLFQE-IVLKSTAFNVIIMLLVLANAIVAAGLHFNHDELTQTNGFY-YAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHCMW---------YRTQLTYFQVLRIFRLMK---ASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEP----KFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIP-NDWA----QQLFSTFSGIYFILINLIFSFAFMSMFQILTQKGWVIVMHDTMDMAKHRGLNALVAIY 2173
            FHF     +  +++  ++ EGW  ++Y+A+D   +  G  Y         FI  I  +A+ + N+F+  +  TF E    +++     KNQ       +        K  P+    P    P  +Q   V+ S+ F  ++  L++ N I     H+N  E  Q N       + FTI+F +E V K+     + Y+    + F+F++ +G+ +  +           R    +F++ R+ RL+K    +  +    +    S + L  + L    L  I + + +Q+F  I + +     + + F  FP+A L +F   T E W E++          P +D+A        + F+  YFI   ++ +F  +++F  +    +  +  D   +  H  L+   AI+
Sbjct:  995 FHFDNVLSAMMSLFTVSTFEGWPQLLYKAIDSNEEDTGPVYNNRVEMAIFFIIYIILIAFFMMNIFVGFVIVTFQEQGETEYKNCELDKNQRQCVQYAL--------KARPLRCYIPKN--PYQYQVWYVVTSSYFEYLMFALIMLNTICLGMQHYNQSE--QMNHISDILNVAFTIIFTLEMVLKLIAFKPRGYFGDPWNVFDFLIVIGSIIDVILSEIDDPDESARISSAFFRLFRVMRLVKLLNRAEGVRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMFGKIAMVDGTQINRNNNFQTFPQAVLLLFRCATGEAWQEILLACSYGKLCDPESDYAPGEEHTCGTNFAYYYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHH-LDEFKAIW 1387

[Close]

BLAST of Voltage-dependent calcium channel vs. Ensembl Mouse
Match: Cacna1c (calcium channel, voltage-dependent, L type, alpha 1C subunit [Source:MGI Symbol;Acc:MGI:103013])

HSP 1 Score: 179.489 bits (454), Expect = 2.293e-44
Identity = 177/668 (26.50%), Postives = 305/668 (45.66%), Query Frame = 2

Query: 3074 VMIFVTTTSCISMAFETPTKRVM--NTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTKLKLSGDSPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEI-RDVIKARVGRINVIYIH---------LFVFIGCLIGLTLFVGVVIANYSENK----GTALLTVDQRRWLD--LKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILAS--FNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKYGE--NLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCM----VQPPFCTYRENFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFIKAFYVRFLLRLIPKDRVGF 4999
            +++F    S IS+A E P +     N I L   + +F    TIE+ALK+ A G      +  R++  +LD  +  + +  +++ I+   I      +IL +LR LRPLR       ++ VV  +    R I  + ++  +  F FA  GV +F GKL  C+D +K  + +C G +     +T      D P  + PR W N + F+FDN+  AM+ LF V + EGW E+    I +       IY +         +++ I     + +FVG VI  + E          L  +QR+ ++  LK R         P R  + ++  Q +                     V+ +    YF+ +  +++L+N I L         YG      +A    N+ +T +F +E  LK+ A    GY+    N++D ++   S+I V +  +     NSR+ S  F  +  ++R   +  +   ++ L+ T + S     +V + + +L  +YA+ G+ +FG +   +   + R+ NF    +++ LLFR  TGE W  IM  CM      P          ++ CG+  A + YF SFY++  ++++N+ VA+IM+NF   Y   + +I+  + +  F++ W   D   KG IK   V  LLR I +  +GF
Sbjct:  930 LILFFILLSSISLAAEDPVQHTSFRNHI-LFYFDIVFTTIFTIEIALKMTAYGAFLHKGSFCRNYFNILDLLV--VSVSLISFGIQSSAINV---VKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNY-----ITYKDGEVDHP-IIQPRSWENSK-FDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKAR---------PLRRYIPKNQHQYK---------------------VWYVVNSTYFEYLMFVLILLNTICLAM-----QHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNSAEENSRI-SITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA-VFYFISFYMLCAFLIINLFVAVIMDNFD--YLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRI-QPPLGF 1544

HSP 2 Score: 99.3673 bits (246), Expect = 5.291e-20
Identity = 93/357 (26.05%), Postives = 166/357 (46.50%), Query Frame = 2

Query: 3056 VTYLDW----VMIFVTT-TSCISMAFETP----TKRVMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICII--FVAYMIRVDTIGSGSGK------QILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKL--------AICNDPTKTEKKDCV---GVFDRKISVTKLKLSGDSPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVGRI-NVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVD-------QRRWLDLKGRIK-LTQPLHIPPRPK---MRQDSTQNR 4006
            ++ ++W    ++I +T   +C+++A   P         N+  L+  EY+F +  T+E  LKV+A G +F P A +R+   +LDF I ++ +    +    + D   +  GK      + L   R LRPLR+   VP ++ V+  +++    +L +++L++  +  +A+ G+ +F GK+         I + P + +   C    G   +  + T  K   D P   +          NFDN   AMLT+F+ +++EGW ++   +   VGR    IY    + IG    L L +GV+   +S+ +  A    D       Q+   DLKG +  +TQ   I P  +   M +D  +NR
Sbjct:  118 ISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNS-NLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIIDVPAEEDPSPCALETGHGRQCQNGTVCKPGWDGPKHGIT---------NFDNFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEDKPRNR 464

HSP 3 Score: 72.0182 bits (175), Expect = 9.979e-12
Identity = 130/617 (21.07%), Postives = 238/617 (38.57%), Query Frame = 2

Query:  368 YVTYLLDIVVALLFTAEMFTKMKIKGIIRPSPYVIVRHLFFVKVSNNIENKRPHAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILH---------RSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSY---------FISMIFFLAWLVKNVFIAILTETFAEIRVQFQQMWSPKNQTDADSSKIFQTDGQRWKLVPVYESKP-HGLAPKLFQEI----VLKSTAFNVIIMLLVLANAIVAAGLHFNHDELTQTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHCMWYRTQ---------LTYFQVLRIFRLMK---ASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEP----KFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPN-------DWAQQLFSTFSGIYFILINLIFSFAFMSMF 2080
            ++ +  DIV   +FT E+  KM   G             F  K S          + R+++   D ++V    IS  IQ+   + V+K                   +L  LR  RPL   R +           R K + H         R+   +  VT  L F   ++A +GVQ F   +  +    S+ +++ +     I        +K G+     ++     NS  D      F     +   ++  ++ EGW  ++YR++D   + KG  Y         FI  I  +A+ + N+F+  +  TF E             Q + +         QR  +    +++P     PK   +     V+ ST F  ++ +L+L N I  A  H+    L +        ++FT LF +E + K+     K Y+    + F+F++ +G+ +  +   T          +T+F++ R+ RL+K       +    +    S + L  + L    L  I + + +Q+F  I + +     + + F  FP+A L +F   T E W ++M   M   K  P        +      S+F+  YFI   ++ +F  +++F
Sbjct:  956 HILFYFDIVFTTIFTIEIALKMTAYGA------------FLHKGS----------FCRNYFNILDLLVVSVSLISFGIQS-SAINVVK-------------------ILRVLRVLRPL---RAI----------NRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQF---MFACIGVQLFKGKL--YTCSDSSKQTEAECKGNYI-------TYKDGEVDHPIIQPRSWENSKFD------FDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQE-------------QGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKI-AMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNSAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLF 1485

HSP 4 Score: 65.0846 bits (157), Expect = 1.425e-9
Identity = 70/278 (25.18%), Postives = 117/278 (42.09%), Query Frame = 2

Query:  524 PHAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGL--LSTLRSPRPLILTR-------VLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQ-WKGVSYFISMIFFLAWLVKNVFIAILTETF------AEIRVQFQQMWSPKNQTDAD 1309
            P+AYLR+ W   D I+V+    S          +++  T  D    L      + +  L   R  RPL L         VL S +K  +P      +LH        + + +LF + +YAI+G++ F   ++  C  Q   E  I +     P S C  +   G  C     C    +  +   G   F  F F+  TV+Q  + EGW  ++Y   D + + W  + YF+++I   ++ V N+ + +L+  F      A+ R  FQ++   K Q + D
Sbjct:  187 PNAYLRNGWNLLDFIIVVVGLFS---------AILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVP------LLH--------IALLVLFVIIIYAIIGLELFMGKMHKTCYNQ---EGIIDVPAEEDP-SPCALETGHGRQCQNGTVCKPGWDGPKH--GITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDWPWI-YFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLRE-KQQLEED 433

HSP 5 Score: 54.6842 bits (130), Expect = 2.037e-6
Identity = 56/209 (26.79%), Postives = 100/209 (47.85%), Query Frame = 2

Query: 4226 IFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLI-WVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGS-VKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRENFWQSDCGNFQASL--IYFCSFYIMITYIMLNVLVAIIMENFS 4840
            +F  E  LK+ +L    Y+ S  N +D  +    ++  + V   +       V+         LLR F I     +L  L+ ++L S+     +++ +FL +++++L G+ LFG    + E   R + F N  +S+  +F+I+TGEDWN +M+D ++                 +F   L  IYF   +I   YI+LNV +AI ++N +
Sbjct:  591 LFTAEMLLKMYSLGLQAYFVSLFNRFDCFIVCGGILETILVETKIMSPLGISVLR-----CVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIM------------AYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLA 782

HSP 6 Score: 53.1434 bits (126), Expect = 4.801e-6
Identity = 60/241 (24.90%), Postives = 111/241 (46.06%), Query Frame = 2

Query: 1409 VLKSTAFNVIIMLLVLANAIVAAGLHFNHDE-LTQTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFE-FILCLG--------TTVHCMWYRTQLTYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFC---SIQIYEPKFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPNDWAQQLFSTFSG----IYFILINLIFSFAFMSMF 2080
             +KS  F  +++ LV  N +  A  H+N    LT+      A      LF  E + K++ LG ++Y+    ++F+ FI+C G        T +      + L   ++LRIF++ +    L +    +  S + +  L+L     +II S + +QLF    +    + +   F NFP++ L +F ++T E W  VM   ++ A   P         +F G    IYFI++ +  ++  +++F
Sbjct:  545 AVKSNVFYWLVIFLVFLNTLTIASEHYNQPHWLTEVQD--TANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFIVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIM-AYGGP---------SFPGMLVCIYFIILFICGNYILLNVF 773

[Close]

BLAST of Voltage-dependent calcium channel vs. Ensembl Mouse
Match: Cacna1c (calcium channel, voltage-dependent, L type, alpha 1C subunit [Source:MGI Symbol;Acc:MGI:103013])

HSP 1 Score: 177.178 bits (448), Expect = 1.214e-43
Identity = 178/679 (26.22%), Postives = 307/679 (45.21%), Query Frame = 2

Query: 3074 VMIFVTTTSCISMAFETPTKRVM--NTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTKLKLSGDSPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEI-RDVIKARVGRINVIYIH---------LFVFIGCLIGLTLFVGVVIANYSENK----GTALLTVDQRRWLD--LKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILAS--FNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNH-----------NSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKYGE--NLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCM----VQPPFCTYRENFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFIKAFYVRFLLRLIPKDRVGF 4999
            +++F    S IS+A E P +     N I L  A+Y+F    T+E+ LK+ A G      +  R++  +LD  +  + +  +++ I+   I      +IL +LR LRPLR       ++ VV  +    R I  + ++  +  F FA  GV +F GKL  C+D +K  + +C G +     +T      D P  + PR W N + F+FDN+  AM+ LF V + EGW E+    I +       IY +         +++ I     + +FVG VI  + E          L  +QR+ ++  LK R         P R  + ++  Q +                     V+ +    YF+ +  +++L+N I L         YG      +A    N+ +T +F +E  LK+ A    GY+    N++D ++   S+I V +  +    H           NSR+ S  F  +  ++R   +  +   ++ L+ T + S     +V + + +L  +YA+ G+ +FG +   +   + R+ NF    +++ LLFR  TGE W  IM  CM      P          ++ CG+  A + YF SFY++  ++++N+ VA+IM+NF   Y   + +I+  + +  F++ W   D   KG IK   V  LLR I +  +GF
Sbjct:  905 LILFFILLSSISLAAEDPVQHTSFRNHI-LGNADYVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLV--VSVSLISFGIQSSAINV---VKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNY-----ITYKDGEVDHP-IIQPRSWENSK-FDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKAR---------PLRRYIPKNQHQYK---------------------VWYVVNSTYFEYLMFVLILLNTICLAM-----QHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSMSAEENSRI-SITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA-VFYFISFYMLCAFLIINLFVAVIMDNFD--YLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRI-QPPLGF 1530

HSP 2 Score: 124.405 bits (311), Expect = 1.334e-27
Identity = 164/668 (24.55%), Postives = 295/668 (44.16%), Query Frame = 2

Query: 3056 VTYLDW----VMIFVTT-TSCISMAFETP----TKRVMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICI--IFVAYMIRVDTIGSGSGK------QILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKL--------AICNDPTKTEKKDCV---GVFDRKISVTKLKLSGDSPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVG-RINVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVD-------QRRWLDLKGRIK-LTQPLHIPPRPK---MRQDSTQN-----------RTDNNAINENSFDN-------RVIKVRCWVYDLTQHIYFKRVSAIMVLIN-----CIFLYFPWNN----DDEYGMKR--SKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYD-MVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGS-VKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRENFWQSDCGNFQASL--IYFCSFYIMITYIMLNVLVAIIMENFS 4840
            ++ ++W    ++I +T   +C+++A   P         N+  L+  EY+F +  T+E  LKV+A G +F P A +R+   +LDF I ++ +    +    + D   +  GK      + L   R LRPLR+   VP ++ V+  +++    +L +++L++  +  +A+ G+ +F GK+         I + P + +   C    G   +  + T  K   D P   +          NFDN   AMLT+F+ +++EGW ++   ++  +G  +  +Y    V  G    L L +GV+   +S+ +  A    D       Q+   DLKG +  +TQ   I P  +   M +D  +N            T+N A  +   +N       R+ K +   Y    + + +R     V  N      IFL F  N      + Y      +++  + N     +F  E  LK+ +L    Y+ S  N +D  +V    L  + V   +       V+         LLR F I     +L  L+ ++L S+     +++ +FL +++++L G+ LFG    + E   R + F N  +S+  +F+I+TGEDWN +M+D ++                 +F   L  IYF   +I   YI+LNV +AI ++N +
Sbjct:  118 ISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNS-NLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIIDVPAEEDPSPCALETGHGRQCQNGTVCKPGWDGPKHGI---------TNFDNFAFAMLTVFQCITMEGWTDVLYWMQDAMGYELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEDKPRNMSMPTSETESVNTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVF-LNTLTIASEHYNQPHWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFIVCGGILETILVETKIMSPLGISVLR-----CVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIM------------AYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLA 757

HSP 3 Score: 91.6633 bits (226), Expect = 1.192e-17
Identity = 136/608 (22.37%), Postives = 239/608 (39.31%), Query Frame = 2

Query:  524 PHAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGL--LSTLRSPRPLILTR-------VLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWLVKNVFIAILTETF------AEIRVQFQQM---------------W-------SPKNQTDADSSKIFQTDGQRWKLVPVYESK---------------------PHGLAPKLFQE--------------IVLKSTAFNVIIMLLVLANAIVAAGLHFNHDE-LTQTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFE-FILCLG--------TTVHCMWYRTQLTYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFC---SIQIYEPKFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPNDWAQQLFSTFSG----IYFILINLIFSFAFMSMF 2080
            P+AYLR+ W   D I+V+    S          +++  T  D    L      + +  L   R  RPL L         VL S +K  +P      +LH        + + +LF + +YAI+G++ F   ++  C  Q   E  I +     P S C  +   G  C     C    +    + G   F  F F+  TV+Q  + EGW  ++Y   D +       YF+S++ F ++ V N+ + +L+  F      A+ R  FQ++               W        P+N+ +         D  R   +P  E++                      H ++   F                  +KS  F  +++ LV  N +  A  H+N    LT+      A      LF  E + K++ LG ++Y+    ++F+ FI+C G        T +      + L   ++LRIF++ +    L +    +  S + +  L+L     +II S + +QLF    +    + +   F NFP++ L +F ++T E W  VM   ++ A   P         +F G    IYFI++ +  ++  +++F
Sbjct:  187 PNAYLRNGWNLLDFIIVVVGLFS---------AILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVP------LLH--------IALLVLFVIIIYAIIGLELFMGKMHKTCYNQ---EGIIDVPAEEDP-SPCALETGHGRQCQNGTVCKPGWDG--PKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWMQDAMGYELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEG-----MDEDKPRNMSMPTSETESVNTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPHWLTEVQD--TANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFIVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIM-AYGGP---------SFPGMLVCIYFIILFICGNYILLNVF 748

HSP 4 Score: 67.781 bits (164), Expect = 1.769e-10
Identity = 110/530 (20.75%), Postives = 210/530 (39.62%), Query Frame = 2

Query:  662 LITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILH---------RSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSY---------FISMIFFLAWLVKNVFIAILTETFAEIRVQFQQMWSPKNQTDADSSKIFQTDGQRWKLVPVYESKP-HGLAPKLFQEI----VLKSTAFNVIIMLLVLANAIVAAGLHFNHDELTQTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHCMWYRTQ--------------------LTYFQVLRIFRLMK---ASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEP----KFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPN-------DWAQQLFSTFSGIYFILINLIFSFAFMSMF 2080
            LI+F  +   ++ ++  R L + R LR+         R K + H         R+   +  VT  L F   ++A +GVQ F   +  +    S+ +++ +     I        +K G+     ++     NS  D      F     +   ++  ++ EGW  ++YR++D   + KG  Y         FI  I  +A+ + N+F+  +  TF E             Q + +         QR  +    +++P     PK   +     V+ ST F  ++ +L+L N I  A  H+    L +        ++FT LF +E + K+     K Y+    + F+F++ +G+ +  +   T                     +T+F++ R+ RL+K       +    +    S + L  + L    L  I + + +Q+F  I + +     + + F  FP+A L +F   T E W ++M   M   K  P        +      S+F+  YFI   ++ +F  +++F
Sbjct:  981 LISFGIQSSAINVVKILRVLRVLRPLRAI-------NRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQF---MFACIGVQLFKGKL--YTCSDSSKQTEAECKGNYI-------TYKDGEVDHPIIQPRSWENSKFD------FDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQE-------------QGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKI-AMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSMSAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLF 1471

[Close]

BLAST of Voltage-dependent calcium channel vs. UniProt/SwissProt
Match: sp|Q8BXR5|NALCN_MOUSE (Sodium leak channel non-selective protein OS=Mus musculus OX=10090 GN=Nalcn PE=1 SV=2)

HSP 1 Score: 1487.63 bits (3850), Expect = 0.000e+0
Identity = 871/1923 (45.29%), Postives = 1187/1923 (61.73%), Query Frame = 2

Query:  164 ERKTSHTRETQPTLPGVEFATDDA-GDLTSVNWVYTTWARCAFKIXXXXXXXXXXXNTPETFKEYKWLFYVTYLLDIVVALLFTAEMFTKMKIKGIIRPSPYVIVRHLFFVKVSNNIENKRPHAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANS--IEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWLVKNVFIAILTETFAEIRVQFQQMWSPKNQTDADSS-KIFQTDGQR-WKLVPVYESKPHGLAPKLFQEIVLKSTAFNVIIMLLVLANAIVAAGLHFNHDELT-QTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHCM--WYRTQLTYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEPKFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPNDWAQQLFSTFSGIYFILINLIFSFAFMSMFQILTQKGWVIVMHDTMDMAKHRGLNALVAIYFVFYHLFVTLIVLSLFVAVILDNLELEEDIKKLKQLKLREMSAETQQKLPMRLRIFEKFPNRPQMIKPARLLSDFLIPKIRDSFMRQFAQLPTLEEENESDEMIAAAVSGVGVSSL--PRALSIEIKR-----------QIRGLKGNDKLNAIIYLINESNKTRMIE-----QPIIYPTRSLLSTQHQIRTERRNLRNRMAATTMSINQKPRLNGEIRNMDFETNRKTEEANHFDIKILQQKAEQAEIKRNQQVDDLRENHPYFDKPLFTIGRESQFRQLCRMLVEAQY---KPDINSENPEKQTFYKLQKFFGLVTYLDWVMIFVTTTSCISMAFETPTKRVMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTK-----LKLSGDSPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVGRINVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVDQRRWLDLKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRE-NFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFIKAFYVRF-LLRLIPKDRVGFDFTKKKDQQLFKEMCYEVELLRGGKDKEVSFHDVLTMLAYRSVDISKTXXXXXXXXXXXXXXXXXXXXXRQTIATWIERCIFRNR---QKHGDLKFGLRESNEMVIPIFDDKKEGLGLDRSRKISSGAYQTKFLSLPTLDGRQNTSDGSLPSSGITIGRLNDHLKNQPMGFKRRRSVKKNSSTNQTLTEVSEDELNDELNDIVPTQDPDLTPNQ--LPSLSDSHVPIENSISS-------RSEDK----HLTELVD-ADC-HEVKSWWHVQINTD 5770
            +RK S   E QP     +F  D++  D   + W+   W     +I A++S+ SV  NTP TF+ Y  L YVT+ LD ++  L+TAEM  KM I+GI+                      K   +Y++  W  FD  MV CLW+S+ +Q FE+  ++   +P             +G+L   R PRPLI+ R  R + +F LP+TR+  IL RS  Q+++V++FLLFF+ LY ILGVQ FG    +HCV+      ++    LAIPD+ C+P+ + G  CP   KC+ + +      E GY+GF     S FTVY+A+SQEGWVF+MYRA+D  P+W+   YFI++IFFLAWLVKNVFIA++ ETFAEIRVQFQQMW  ++ T + ++ ++F  D    W+LV V  +KP G AP   Q++ ++S+ F++ I+ +V  + IVAA  ++  +    Q + FY AE+ FT+LF++EA+ KIWCLG+  Y   SLHKFE +L +GTT+H     Y +Q TYFQVLR+ RL+K SP LEDF +KIFG GKKLG L++FT+ LLI+ S++SLQ+FC ++    + DR                                          F+TF              AFMSMFQILTQ+GWV VM  T++   H     LVAIYF+ YHLF TLI+LSLFVAVILDNLEL+ED+KKLKQLK  E +A+T++KLP+RLRIFEKFPNRPQM+K ++L SDF +PKIR+SFM+QF     ++ + +    +   +     SS   P+  + E  +            IR     +K  A+  ++    + RM+      QP     RS+LS QH IR ERR+LR+   + +  I++   L    ++       +  +    +IK++Q+K EQAE+KR  Q ++LRENHPYFDKPLF +GRE +FR  CR++V A++   K D  +   +   +++L    GLVTYLDWVMI VT  SCISM FE+P +RVM+   L++AEY+F + M+IE+ LK++A+G  FTP AV+RDFGGV+D FIY++ +IF+ +M +   + + SG Q+LM+LRCLRPLRIF LVP MR+VV EL  GF+EI +VS+LL+  M  FA +GV +F GKLA CNDP    ++DC G+F   +SV+K     L+     P F VPRVWANPRNFNFDN+GNAML LFEVLSL+GWVE+RDVI  RVG I+ IYIH+FVF+GC+IGLTLFVGVVIAN++ENKGTALLTVDQRRW DLK R+K+ QPLH+PPRP           DN+              R  +YD+TQH +FKR  A++VL   + L   W+ DD   +     LA+ +V +TFIF +E  +KI A+S  G+WQS+RN YD++VT L ++WV +H ++ + +   +     G   ++ RFFSI GKHVTLKML+ TV++SM+KS F+I+ MFLL+L YA AG++LFG+VKYGEN+ RHANF +  ++I +LFRIVTGEDWNKIMHDCMVQPPFCT  E  +W +DCGN+  +L+YFCSFY++I YIMLN+LVAII+ENFSLFYS +ED ++SYND+R+FQ  WN +D  R+G I  F V+F L  L  +  V  D    KD+ LFK MCYE+E L  G D  V+FHDVL+ML+YRSVDI K+LQLEELLARE+LEY IEEEVA+QTI  W+++C+ R R   Q+   +   LRES E               +RSR          FL+ P+++  Q + D +  S         DH            S++  +S+ Q L   +  +      D   T  P     Q  LPS      PI +S+SS       R+  K     +  + D A C  EVK WW  Q+  +
Sbjct:    3 KRKQSSRVEAQPV---TDFGPDESLSDNADILWINKPWVHSLLRICAIISVISVCMNTPMTFEHYPPLQYVTFTLDTLLMFLYTAEMIAKMHIRGIV----------------------KGDSSYVKDRWCVFDGFMVFCLWVSLVLQVFEIADIVDQMSP-------------WGML---RIPRPLIMIRAFRIYFRFELPRTRITNILKRSGEQIWSVSIFLLFFLLLYGILGVQMFGT-FTYHCVVNDTKPGNVTWNSLAIPDTHCSPELEEGYQCPPGFKCMDLEDLGLSRQELGYSGFNEIGTSIFTVYEASSQEGWVFLMYRAIDSFPRWRSYFYFITLIFFLAWLVKNVFIAVIIETFAEIRVQFQQMWGTRSSTTSTATTQMFHEDAAGGWQLVAVDVNKPQGRAPACLQKM-MRSSVFHMFILSMVTVDVIVAASNYYKGENFRRQYDEFYLAEVAFTVLFDLEALLKIWCLGFTGYISSSLHKFELLLVIGTTLHVYPDLYHSQFTYFQVLRVVRLIKISPALEDFVYKIFGPGKKLGSLVVFTASLLIVMSAISLQMFCFVE----ELDR------------------------------------------FTTFPR------------AFMSMFQILTQEGWVDVMDQTLNAVGHM-WAPLVAIYFILYHLFATLILLSLFVAVILDNLELDEDLKKLKQLKQSEANADTKEKLPLRLRIFEKFPNRPQMVKISKLPSDFTVPKIRESFMKQF-----IDRQQQDTCCLFRILPSTSSSSCDNPKKPTAEDNKYIDQKLRKSVFSIRARNLLEKETAVTKILRACTRQRMLSGSFEGQPA--KERSILSVQHHIRQERRSLRH--GSNSQRISRGKSLETLTQDHSNTVRYRNAQREDSEIKMIQEKKEQAEMKRKVQEEELRENHPYFDKPLFIVGREHRFRNFCRVVVRARFNASKTDPVTGAVKNTKYHQLYDLLGLVTYLDWVMITVTICSCISMMFESPFRRVMHAPTLQIAEYVFVIFMSIELNLKIMADGLFFTPTAVIRDFGGVMDIFIYLVSLIFLCWMPQ--NVPAESGAQLLMVLRCLRPLRIFKLVPQMRKVVRELFSGFKEIFLVSILLLTLMLVFASFGVQLFAGKLAKCNDPNIIRREDCNGIFRINVSVSKNLNLKLRPGEKKPGFWVPRVWANPRNFNFDNVGNAMLALFEVLSLKGWVEVRDVIIHRVGPIHGIYIHVFVFLGCMIGLTLFVGVVIANFNENKGTALLTVDQRRWEDLKSRLKIAQPLHLPPRP-----------DNDGF------------RAKMYDITQHPFFKRTIALLVLAQSVLLSVKWDVDDPVTVP----LATMSVVFTFIFVLEVTMKIIAMSPAGFWQSRRNRYDLLVTSLGVVWVVLHFALLNAYTYMM-----GACVIVFRFFSICGKHVTLKMLLLTVVVSMYKSFFIIVGMFLLLLCYAFAGVVLFGTVKYGENINRHANFSSAGKAITVLFRIVTGEDWNKIMHDCMVQPPFCTPDEFTYWATDCGNYAGALMYFCSFYVIIAYIMLNLLVAIIVENFSLFYSTEEDQLLSYNDLRHFQIIWNMVDDKREGVIPTFRVKFLLRLLRGRLEVDLD----KDKLLFKHMCYEMERLHNGGD--VTFHDVLSMLSYRSVDIRKSLQLEELLAREQLEYTIEEEVAKQTIRMWLKKCLKRIRAKQQQSCSIIHSLRESQEQ--------------ERSR----------FLNPPSIETTQPSEDSNANS--------QDH------------SMQPETSSQQQLLSPTLSDRGGSRQDAADTGKPQRKIGQWRLPSAPK---PISHSVSSVNLRFGGRTTMKTVVCKMNPMPDTASCGSEVKKWWTRQLTVE 1727

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BLAST of Voltage-dependent calcium channel vs. UniProt/SwissProt
Match: sp|Q6Q760|NALCN_RAT (Sodium leak channel non-selective protein OS=Rattus norvegicus OX=10116 GN=Nalcn PE=1 SV=1)

HSP 1 Score: 1484.55 bits (3842), Expect = 0.000e+0
Identity = 864/1920 (45.00%), Postives = 1187/1920 (61.82%), Query Frame = 2

Query:  164 ERKTSHTRETQPTLPGVEFATDDA-GDLTSVNWVYTTWARCAFKIXXXXXXXXXXXNTPETFKEYKWLFYVTYLLDIVVALLFTAEMFTKMKIKGIIRPSPYVIVRHLFFVKVSNNIENKRPHAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANS--IEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWLVKNVFIAILTETFAEIRVQFQQMWSPKNQTDADSS-KIFQTDGQR-WKLVPVYESKPHGLAPKLFQEIVLKSTAFNVIIMLLVLANAIVAAGLHFNHDELT-QTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHCM--WYRTQLTYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEPKFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPNDWAQQLFSTFSGIYFILINLIFSFAFMSMFQILTQKGWVIVMHDTMDMAKHRGLNALVAIYFVFYHLFVTLIVLSLFVAVILDNLELEEDIKKLKQLKLREMSAETQQKLPMRLRIFEKFPNRPQMIKPARLLSDFLIPKIRDSFMRQFAQLPTLEEENESDEMIAAAVSGVGVSSL--PRALSIEIKR-----------QIRGLKGNDKLNAIIYLINESNKTRMIE-----QPIIYPTRSLLSTQHQIRTERRNLRNRMAATTMSINQKPRLNGEIRNMDFETNRKTEEANHFDIKILQQKAEQAEIKRNQQVDDLRENHPYFDKPLFTIGRESQFRQLCRMLVEAQY---KPDINSENPEKQTFYKLQKFFGLVTYLDWVMIFVTTTSCISMAFETPTKRVMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTK-----LKLSGDSPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVGRINVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVDQRRWLDLKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRE-NFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFIKAFYVRF-LLRLIPKDRVGFDFTKKKDQQLFKEMCYEVELLRGGKDKEVSFHDVLTMLAYRSVDISKTXXXXXXXXXXXXXXXXXXXXXRQTIATWIERCIFRNRQKHGDLKFGLRESNEMVIPIFDDKKEGLGLDRSRKISSGAYQTKFLSLPTLDGRQNTSDGSLPSSGITIGRLNDHLKNQPMGFKRRRSVKKNSSTNQTLTEVSEDELNDELNDIVPTQDPDLTPNQ--LPSLSDSHVPIENSISS-----------RSEDKHLTELVD-ADC-HEVKSWWHVQINTD 5770
            +RK S   E QP     +F  D++  D   + W+   W     +I A++S+  V  NTP TF+ Y  L YVT+ LD ++  L+TAEM  KM I+GI+                      K   +Y++  W  FD  MV CLW+S+ +Q FE+  ++   +P             +G+L   R PRPLI+ R  R + +F LP+TR+  IL RS  Q+++V++FLLFF+ LY ILGVQ FG    +HCV+      ++    LAIPD+ C+P+ + G  CP   KC+ + +      E GY+GF     S FTVY+A+SQEGWVF+MYRA+D  P+W+   YFI++IFFLAWLVKNVFIA++ ETFAEIRVQFQQMW  ++ T + ++ ++F  D    W+LV V  +KP G AP   Q++ ++S+ F++ I+ +V  + IVAA  ++  +    Q + FY AE+ FT+LF++EA+ KIWCLG+  Y   SLHKFE +L +GTT+H     Y +Q TYFQVLR+ RL+K SP LEDF +KIFG GKKLG L++FT+ LLI+ S++SLQ+FC ++    + DR                                          F+TF              AFMSMFQILTQ+GWV VM  T++   H     LVAIYF+ YHLF TLI+LSLFVAVILDNLEL+ED+KKLKQLK  E +A+T++KLP+RLRIFEKFPNRPQM+K ++L SDF +PKIR+SFM+QF     ++ + +    +   +     SS   P+  ++E  +            IR     +K  A+  ++    + RM+      QP     RS+LS QH IR ERR+LR+   + +  I++   L    ++       +  +    +IK++Q+K EQAE+KR  Q ++LRENHPYFDKPLF +GRE +FR  CR++V A++   K D  +   +   +++L    GLVTYLDWVMI VT  SCISM FE+P +RVM+   L++AEY+F + M+IE+ LK++A+G  FTP AV+RDFGGV+D FIY++ +IF+ +M +   + + SG Q+LM+LRCLRPLRIF LVP MR+VV EL  GF+EI +VS+LL+  M  FA +GV +F GKLA CNDP    ++DC G+F   +SV+K     L+     P F VPRVWANPRNFNFDN+GNAML LFEVLSL+GWVE+RDVI  RVG I+ IYIH+FVF+GC+IGLTLFVGVVIAN++ENKGTALLTVDQRRW DLK R+K+ QPLH+PPRP           DN+              R  +YD+TQH +FKR  A++VL   + L   W+ +D   +     LA+ +V +TFIF +E  +KI A+S  G+WQS+RN YD++VT L ++WV +H ++ + +   +     G   ++ RFFSI GKHVTLKML+ TV++SM+KS F+I+ MFLL+L YA AG++LFG+VKYGEN+ RHANF +  ++I +LFRIVTGEDWNKIMHDCMVQPPFCT  E  +W +DCGN+  +L+YFCSFY++I YIMLN+LVAII+ENFSLFYS +ED ++SYND+R+FQ  WN +D  R+G I  F V+F L  L  +  V  D    KD+ LFK MCYE+E L  G D  V+FHDVL+ML+YRSVDI K+LQLEELLARE+LEY IEEEVA+QTI  W+++C+ R R K        ++S  ++  + + +++ L              ++FL+ P+++  Q + D +  S         DH   QP            SS+ Q L   +  +      D   T  P     Q  LPS      PI +S+SS           +S    +  + D A C  EVK WW  Q+  +
Sbjct:    3 KRKQSSRVEAQPV---TDFGPDESLSDNADILWINKPWVHSLLRICAIISVIPVCMNTPMTFEHYPPLQYVTFTLDTLLMFLYTAEMIAKMHIRGIV----------------------KGDSSYVKDRWCVFDGFMVFCLWVSLVLQVFEIADIVDQMSP-------------WGML---RIPRPLIMIRAFRIYFRFELPRTRITNILKRSGEQIWSVSIFLLFFLLLYGILGVQMFGT-FTYHCVVNDTKPGNVTWNSLAIPDTHCSPELEEGYQCPPGFKCMDLEDLGLSRQELGYSGFNEIGTSIFTVYEASSQEGWVFLMYRAIDSFPRWRSYFYFITLIFFLAWLVKNVFIAVIIETFAEIRVQFQQMWGTRSSTTSTATTQMFHEDAAGGWQLVAVDVNKPQGRAPACLQKM-MRSSVFHMFILSMVTVDVIVAASNYYKGENFRRQYDEFYLAEVAFTVLFDLEALLKIWCLGFTGYISSSLHKFELLLVIGTTLHVYPDLYHSQFTYFQVLRVVRLIKISPALEDFVYKIFGPGKKLGSLVVFTASLLIVMSAISLQMFCFVE----ELDR------------------------------------------FTTFPR------------AFMSMFQILTQEGWVDVMDQTLNAVGHM-WAPLVAIYFILYHLFATLILLSLFVAVILDNLELDEDLKKLKQLKQSEANADTKEKLPLRLRIFEKFPNRPQMVKISKLPSDFTVPKIRESFMKQF-----IDRQQQDTCCLFRILPSTSSSSCDNPKRPTVEDNKYIDQKLRKSVFSIRARNLLEKETAVTKILRACTRQRMLSGSFEGQPT--KERSILSVQHHIRQERRSLRH--GSNSQRISRGKSLETLTQDHSNTVRYRNAQREDSEIKMIQEKKEQAEMKRKVQEEELRENHPYFDKPLFIVGREHRFRNFCRVVVRARFNASKTDPVTGAVKNTKYHQLYDLLGLVTYLDWVMITVTICSCISMMFESPFRRVMHAPTLQIAEYVFVIFMSIELNLKIMADGLFFTPTAVIRDFGGVMDIFIYLVSLIFLCWMPQ--NVPAESGAQLLMVLRCLRPLRIFKLVPQMRKVVRELFSGFKEIFLVSILLLTLMLVFASFGVQLFAGKLAKCNDPNIIRREDCNGIFRINVSVSKNLNLKLRPGEKKPGFWVPRVWANPRNFNFDNVGNAMLALFEVLSLKGWVEVRDVIIHRVGPIHGIYIHVFVFLGCMIGLTLFVGVVIANFNENKGTALLTVDQRRWEDLKSRLKIAQPLHLPPRP-----------DNDGF------------RAKMYDITQHPFFKRTIALLVLAQSVLLSVKWDVEDPVTVP----LATMSVVFTFIFVLEVTMKIIAMSPAGFWQSRRNRYDLLVTSLGVVWVVLHFALLNAYTYMM-----GACVIVFRFFSICGKHVTLKMLLLTVVVSMYKSFFIIVGMFLLLLCYAFAGVVLFGTVKYGENINRHANFSSAGKAITVLFRIVTGEDWNKIMHDCMVQPPFCTPDEFTYWATDCGNYAGALMYFCSFYVIIAYIMLNLLVAIIVENFSLFYSTEEDQLLSYNDLRHFQIIWNMVDDKREGVIPTFRVKFLLRLLRGRLEVDLD----KDKLLFKHMCYEMERLHNGGD--VTFHDVLSMLSYRSVDIRKSLQLEELLAREQLEYTIEEEVAKQTIRMWLKKCLKRIRAKQ-------QQSCSIIHSLRESQQQEL--------------SRFLNPPSIETTQPSEDTNANS--------QDH-NTQP-----------ESSSQQQLLSPTLSDRGGSRQDAADTGKPQRKIGQWRLPSAPK---PISHSVSSVNLRFGGRTTMKSVVCKMNPMPDTASCGSEVKKWWTRQLTVE 1727

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BLAST of Voltage-dependent calcium channel vs. UniProt/SwissProt
Match: sp|Q8IZF0|NALCN_HUMAN (Sodium leak channel non-selective protein OS=Homo sapiens OX=9606 GN=NALCN PE=1 SV=1)

HSP 1 Score: 1481.85 bits (3835), Expect = 0.000e+0
Identity = 859/1920 (44.74%), Postives = 1185/1920 (61.72%), Query Frame = 2

Query:  164 ERKTSHTRETQPTLPGVEFATDDA-GDLTSVNWVYTTWARCAFKIXXXXXXXXXXXNTPETFKEYKWLFYVTYLLDIVVALLFTAEMFTKMKIKGIIRPSPYVIVRHLFFVKVSNNIENKRPHAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANS--IEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWLVKNVFIAILTETFAEIRVQFQQMWSPKNQTDADSS-KIFQTDGQR-WKLVPVYESKPHGLAPKLFQEIVLKSTAFNVIIMLLVLANAIVAAGLHFNHDELT-QTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHCM--WYRTQLTYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEPKFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPNDWAQQLFSTFSGIYFILINLIFSFAFMSMFQILTQKGWVIVMHDTMDMAKHRGLNALVAIYFVFYHLFVTLIVLSLFVAVILDNLELEEDIKKLKQLKLREMSAETQQKLPMRLRIFEKFPNRPQMIKPARLLSDFLIPKIRDSFMRQFAQLPTLEEENESDEMIAAAVSGVGVSSLPRALSIEIKRQ-------------IRGLKGNDKLNAIIYLINESNKTRMIE-----QPIIYPTRSLLSTQHQIRTERRNLRNRMAATTMSINQKPRLNGEIRNMDFETNRKTEEANHFDIKILQQKAEQAEIKRNQQVDDLRENHPYFDKPLFTIGRESQFRQLCRMLVEAQY---KPDINSENPEKQTFYKLQKFFGLVTYLDWVMIFVTTTSCISMAFETPTKRVMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTK-----LKLSGDSPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVGRINVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVDQRRWLDLKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRE-NFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFIKAFYVRF-LLRLIPKDRVGFDFTKKKDQQLFKEMCYEVELLRGGKDKEVSFHDVLTMLAYRSVDISKTXXXXXXXXXXXXXXXXXXXXXRQTIATWIERCIFRNRQKHGDLKFGLRESNEMVIPIFDDKKEGLGLDRSRKISSGAYQTKFLSLPTLDGRQNTSDGSLPSSGITIGRLNDHLKNQPMGFKRRRSVKKNSSTNQTLTEVSEDELNDELNDIVPTQDPDLTPNQ--LPSLSDSHVPIENSISS-----------RSEDKHLTELVD-ADC-HEVKSWWHVQINTD 5770
            +RK S   E QP     +F  D++  D   + W+   W     +I A++S+ SV  NTP TF+ Y  L YVT+ LD ++  L+TAEM  KM I+GI+                      K   +Y++  W  FD  MV CLW+S+ +Q FE+  ++   +P             +G+L   R PRPLI+ R  R + +F LP+TR+  IL RS  Q+++V++FLLFF+ LY ILGVQ FG    +HCV+      ++    LAIPD+ C+P+ + G  CP   KC+ + +      E GY+GF     S FTVY+AASQEGWVF+MYRA+D  P+W+   YFI++IFFLAWLVKNVFIA++ ETFAEIRVQFQQMW  ++ T + ++ ++F  D    W+LV V  +KP G AP   Q++ ++S+ F++ I+ +V  + IVAA  ++  +    Q + FY AE+ FT+LF++EA+ KIWCLG+  Y   SLHKFE +L +GTT+H     Y +Q TYFQVLR+ RL+K SP LEDF +KIFG GKKLG L++FT+ LLI+ S++SLQ+FC ++    + DR                                          F+TF              AFMSMFQILTQ+GWV VM  T++   H     +VAIYF+ YHLF TLI+LSLFVAVILDNLEL+ED+KKLKQLK  E +A+T++KLP+RLRIFEKFPNRPQM+K ++L SDF +PKIR+SFM+QF     ++ + +    +  ++     SS   +    I+               IR     +K  A+  ++    + RM+      QP     RS+LS QH IR ERR+LR+   + +  I++   L    ++       +  +    +IK++Q+K EQAE+KR  Q ++LRENHPYFDKPLF +GRE +FR  CR++V A++   K D  +   +   +++L    GLVTYLDWVMI VT  SCISM FE+P +RVM+   L++AEY+F + M+IE+ LK++A+G  FTP AV+RDFGGV+D FIY++ +IF+ +M +   + + SG Q+LM+LRCLRPLRIF LVP MR+VV EL  GF+EI +VS+LL+  M  FA +GV +F GKLA CNDP    ++DC G+F   +SV+K     L+     P F VPRVWANPRNFNFDN+GNAML LFEVLSL+GWVE+RDVI  RVG I+ IYIH+FVF+GC+IGLTLFVGVVIAN++ENKGTALLTVDQRRW DLK R+K+ QPLH+PPRP           DN+              R  +YD+TQH +FKR  A++VL   + L   W+ +D   +     LA+ +V +TFIF +E  +KI A+S  G+WQS+RN YD++VT L ++WV +H ++ + +   +     G   ++ RFFSI GKHVTLKML+ TV++SM+KS F+I+ MFLL+L YA AG++LFG+VKYGEN+ RHANF +  ++I +LFRIVTGEDWNKIMHDCMVQPPFCT  E  +W +DCGN+  +L+YFCSFY++I YIMLN+LVAII+ENFSLFYS +ED ++SYND+R+FQ  WN +D  R+G I  F V+F L  L  +  V  D    KD+ LFK MCYE+E L  G D  V+FHDVL+ML+YRSVDI K+LQLEELLARE+LEY IEEEVA+QTI  W+++C+ R R K        ++S  ++  + + +++ L              ++FL+ P+++  Q + D +  S                    +  S++  +S+ Q L   +  +      D      P     Q  LPS      PI +S+SS           +S    +  + D A C  EVK WW  Q+  +
Sbjct:    3 KRKQSSRVEAQPV---TDFGPDESLSDNADILWINKPWVHSLLRICAIISVISVCMNTPMTFEHYPPLQYVTFTLDTLLMFLYTAEMIAKMHIRGIV----------------------KGDSSYVKDRWCVFDGFMVFCLWVSLVLQVFEIADIVDQMSP-------------WGML---RIPRPLIMIRAFRIYFRFELPRTRITNILKRSGEQIWSVSIFLLFFLLLYGILGVQMFGT-FTYHCVVNDTKPGNVTWNSLAIPDTHCSPELEEGYQCPPGFKCMDLEDLGLSRQELGYSGFNEIGTSIFTVYEAASQEGWVFLMYRAIDSFPRWRSYFYFITLIFFLAWLVKNVFIAVIIETFAEIRVQFQQMWGSRSSTTSTATTQMFHEDAAGGWQLVAVDVNKPQGRAPACLQKM-MRSSVFHMFILSMVTVDVIVAASNYYKGENFRRQYDEFYLAEVAFTVLFDLEALLKIWCLGFTGYISSSLHKFELLLVIGTTLHVYPDLYHSQFTYFQVLRVVRLIKISPALEDFVYKIFGPGKKLGSLVVFTASLLIVMSAISLQMFCFVE----ELDR------------------------------------------FTTFPR------------AFMSMFQILTQEGWVDVMDQTLNAVGHM-WAPVVAIYFILYHLFATLILLSLFVAVILDNLELDEDLKKLKQLKQSEANADTKEKLPLRLRIFEKFPNRPQMVKISKLPSDFTVPKIRESFMKQF-----IDRQQQDTCCLLRSLPTTSSSSCDHSKRSAIEDNKYIDQKLRKSVFSIRARNLLEKETAVTKILRACTRQRMLSGSFEGQPA--KERSILSVQHHIRQERRSLRH--GSNSQRISRGKSLETLTQDHSNTVRYRNAQREDSEIKMIQEKKEQAEMKRKVQEEELRENHPYFDKPLFIVGREHRFRNFCRVVVRARFNASKTDPVTGAVKNTKYHQLYDLLGLVTYLDWVMIIVTICSCISMMFESPFRRVMHAPTLQIAEYVFVIFMSIELNLKIMADGLFFTPTAVIRDFGGVMDIFIYLVSLIFLCWMPQ--NVPAESGAQLLMVLRCLRPLRIFKLVPQMRKVVRELFSGFKEIFLVSILLLTLMLVFASFGVQLFAGKLAKCNDPNIIRREDCNGIFRINVSVSKNLNLKLRPGEKKPGFWVPRVWANPRNFNFDNVGNAMLALFEVLSLKGWVEVRDVIIHRVGPIHGIYIHVFVFLGCMIGLTLFVGVVIANFNENKGTALLTVDQRRWEDLKSRLKIAQPLHLPPRP-----------DNDGF------------RAKMYDITQHPFFKRTIALLVLAQSVLLSVKWDVEDPVTVP----LATMSVVFTFIFVLEVTMKIIAMSPAGFWQSRRNRYDLLVTSLGVVWVVLHFALLNAYTYMM-----GACVIVFRFFSICGKHVTLKMLLLTVVVSMYKSFFIIVGMFLLLLCYAFAGVVLFGTVKYGENINRHANFSSAGKAITVLFRIVTGEDWNKIMHDCMVQPPFCTPDEFTYWATDCGNYAGALMYFCSFYVIIAYIMLNLLVAIIVENFSLFYSTEEDQLLSYNDLRHFQIIWNMVDDKREGVIPTFRVKFLLRLLRGRLEVDLD----KDKLLFKHMCYEMERLHNGGD--VTFHDVLSMLSYRSVDIRKSLQLEELLAREQLEYTIEEEVAKQTIRMWLKKCLKRIRAKQ-------QQSCSIIHSLRESQQQEL--------------SRFLNPPSIETTQPSEDTNANS--------------------QDNSMQPETSSQQQLLSPTLSDRGGSRQDAADAGKPQRKFGQWRLPSAPK---PISHSVSSVNLRFGGRTTMKSVVCKMNPMTDAASCGSEVKKWWTRQLTVE 1727

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BLAST of Voltage-dependent calcium channel vs. UniProt/SwissProt
Match: sp|O14234|CCH1_SCHPO (Calcium-channel protein cch1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=cch1 PE=3 SV=1)

HSP 1 Score: 242.276 bits (617), Expect = 9.213e-63
Identity = 203/767 (26.47%), Postives = 363/767 (47.33%), Query Frame = 2

Query: 2843 KAEQAEIKRNQQVDDLRENHPYFDKPLFTIGRESQFRQLCRMLVEAQYKPDINSENPEKQTFYKLQKFFGLVTYLDWVMIFVTTTSCISMAFETPTKRVMNTIELKV------AEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFE-LVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTKLKLSGDSPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEI-RDVI---------KARVGRINVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVDQRRWLDLKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFL---YFPWNNDDEYGMKRSKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFL-LMLVYALAGIILFGSVKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRENFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDED-AIISYNDIRNFQQAWNSIDVNRKGFI-KAFYVRFLLRLIPKDRVGFDFTKKKDQQLFKEMCYEVELLRGGK 5074
            +A +A ++  Q   +  +NHP ++   + I   ++ R+ C+ LV            P  Q  Y++ + F     L  V+I      CI+    TP     + +  K        E  F    TIE A+K++A+GF  TP A +R     +DFF+ +   I +  ++    + S + +      + LR LR+  L    +R+  + L+ GF +I   +V+    +  FA++  ++FGG L  CND        CV          +   + ++     PRVW+NP +++FD   +A+L LFE+ S+EGWV+I R V+         +      N ++  LF  +  +  LTLF+ ++I+NY+E  G+A  T +QR WL+L+ +IK  +P     RP +R                      ++  C+ + + +H  ++R    + +++ +FL   ++P      Y   R+ I    ++ +T   C+    K+  LSF  ++ S  N++D+VVT  SL     +I++     +R ++     + VL+    I  K      L +TV+ S+  S+F +IA ++ L + +A+A   +FG  K G N G + NF +   ++ LLF +  GE WN +MHD  +  P C   ++F+ SDCGN   +   F ++ I+  YI +N+ + ++ +NFS  ++       +  ND R F+ +W   D    G+I K   V+F+L L    R  +DF   +D+   + +  +V+   G +
Sbjct:  882 QAAKAFVRIKQT--EFLKNHPKYNDVFWVIKPSNRIRRFCQRLVMPGVNERYGGVEP-YQWVYRVIQVFIYACILTAVII-----ECIA----TPIYERDHLLNDKQHAWFVWTEVAFATIFTIEAAIKIIADGFCITPNAYLRSTWNCIDFFVLVTLWINLYAVLTSHALLSRAFRA----FKALRVLRLINLTQTSQRMFHDALISGFFKIFSAAVVSATLLIPFALWAKNVFGGLLYSCNDDNVLSASQCV---------LEYASTPNNWEVWAPRVWSNPPDYDFDRFPHALLALFEIASIEGWVDIMRSVMDITGFNNQPQTNASSGNAMFFVLFNLVSMIYILTLFIAIIISNYAERTGSAFFTAEQRAWLELRRKIKSMRP---SKRPAIRPLG-------------------LRGLCYDFAVQKHGIWRRTFTGLYIVHLLFLLTIFYPC--PIAYTYVRNSIFLILSICYTINICV----KVYGLSFYYFFHSFWNMFDVVVTLGSLT---CNIAILAKFENRSLTLLQTTLLVLVTVHLIP-KFDNFDQLSKTVVASL-PSIFSLIATWIVLYITFAIAFNQIFGLTKLGLNGGPNKNFRSIRNALVLLFTMTFGEGWNDVMHDYTISYPNCVNGDDFYNSDCGNKPWAYGLFIAWNIISMYIFVNMFITVVFDNFSYIHTKSSSFTNLQRNDFRQFKDSWAPFDPMVTGYIPKRNAVKFVLSL----RGVYDFRIYRDEHTLRSIISKVQSKTGQQ 1586

HSP 2 Score: 82.4185 bits (202), Expect = 4.374e-14
Identity = 133/606 (21.95%), Postives = 235/606 (38.78%), Query Frame = 2

Query:  371 VTYLLDIVVALLFTAEMFTKMKIKGIIRPSPYVIVRHLFFVKVSNNIENKRPH--AYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDS-FCNPKFKSG-------------DSCPYSMKCVKIANSIEDEGGYA---GFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWLVKNVFIAILTETFAEIRVQFQQMWSPKNQTDADSSKIFQTDGQRWKLVPVYESKPHGLAPKLFQEIVLKSTAFNVIIMLLVLANAIVAAGLHFNHDELTQTNGF-YYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHCM-----------WYRTQLTYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEPKFD---RFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPNDWAQQLFSTFSGIYFILINLIFSFAFMSMFQI 2086
            + YL+ IV+ +L+T EM  K+ + G +            F    N+   K P   +YLRH W   D + ++ LWIS+                    K+    ++ + +++ LR  R L +TR   + LK           L  S+  +  V  F  FF  + AILGVQFF   +N  CV            D  +P   FC   +++G             +  P    C + +     E  Y+    F  F  S   ++   S  G+  IMY  MD       + + IS  F   WL+  V IA++T +F +++       S KNQ +  S                     H +  KL ++ +  S   N I +  ++A  +      ++    T      +YA + F +   +   F  +   ++ ++ R  +  + +L +   V  +           W    L+ F + RI+R +   P        +F + K+L  L+LF   +L I S  +++LF  +       D    F+   ++FL ++ ++T E W +VM         +   W    F T   ++F+  N +    F+++ Q+
Sbjct:  216 IDYLI-IVIGILYTLEMLLKIYLFGFLYDGSSS------FYDFINSYTKKTPRTMSYLRHSWNRVDFVAIVALWISVI------------------GKKQQGIFRLFSMIACLRLTRLLNITRKTETILK----------SLKESSTPLVQVVSFNAFFGVMIAILGVQFFKASLNRQCVWLG------DYGDQYLPTGQFCGGHWENGIKRAYLDKNGFPSNVNPRGFICAEKSVCRVVENPYSNTVSFDNFFNSLELIFVIMSSNGFTDIMYDIMDAEYFVSCLLFIISAYFLTLWLMSLV-IAVVTSSFIDLQ------HSGKNQKEQKS------------------VDKHLIRNKLCEKYLFYS---NFIWISFIVAQFVTLCTQTYDQTSSTANRYLIFYACVDFLLAAEVILRFFAYLPDYRLFFRRYTNLVDIVLAVLNLVTLLPSIRKNPVAFGW----LSIFAIARIYRCILLIPYTRKIAKLLFSNFKQLLNLMLFLVIVLFIASLCAVRLFQDLPNDGDSDDDAISFATTYESFLYMYQILTSENWTDVMFAIQARLAHLHLSWIPGAFFT---LWFLFSNNVVLSMFIAVIQV 745

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BLAST of Voltage-dependent calcium channel vs. UniProt/SwissProt
Match: sp|P50077|CCH1_YEAST (Calcium-channel protein CCH1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=CCH1 PE=1 SV=1)

HSP 1 Score: 198.364 bits (503), Expect = 2.320e-49
Identity = 182/724 (25.14%), Postives = 337/724 (46.55%), Query Frame = 2

Query: 2867 RNQQVDDLRENHPYFDKPLFTIGRESQFRQLCRMLVEAQY--KPDINSENPEKQTFYKLQKFFGLVTYLDWVMIFVTTTSC--ISMAFETPTKRV---MNTIELKVA-EYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYI-ICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCL-VPHMRRVVFELV--RGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTKLKLSGDSPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVG----------RINVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVDQRRWLDLKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLT---QHIYFKRVSAIMVLINCIFLYF-PWNNDDEYGMKRSKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRENFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFY-SNDEDAIISYNDIRNFQQAWNSIDVNRKGFIKAFYV 4957
             ++++D L++ +P F+   +    + +FR+ C+ LV      + D +    +    Y  + +F  +    +V IF   T    +   + TP  R+   M T     A +  F  A +IE  +K +A+GFI++P A +R+    +DF + I + I  +AY+       +G+  +I   L  LR LR  CL + +  R  F LV   G  +I    ++ +  +F F V+G+ IF G+L  CND +   + DC   +   +    +         + PRV+  P   + D+  +A  +L++++SLEGWV++ + +    G            N +++ LF F+  +  L LFV  ++ N +   G+A  T++++ WL+ +  +   +P  IP                N I        + +VR + Y L    ++ Y+     +++ ++ I L    +N  +  G +    + S     T +F I+ AL +       Y++ K N   + +  ++ I   V   V  +H      +N     +L+ F  I  ++ TL  L++T + S+   L +     +L LVYA+A   +FG  + G N   + NF    +S+ +LFR   GE WN IM D  V  P+C+  +N   +DCG+   + +   S+ I+  YI +N+ V++I+ NFS  Y S    + I+ ++I+ + +AW+  D +  G ++  Y+
Sbjct: 1139 EDEKLDYLKK-YPLFNYSYYFFSPQHRFRRFCQRLVPPSTGKRTDGSRFFEDSTDLYNKRSYFHHIERDVFVFIFALATILLIVCSCYVTPLYRMHHKMGTWNWSSALDCAFIGAFSIEFIVKTVADGFIYSPNAYLRNPWNFIDFCVLISMWINLIAYLK-----NNGNLSRIFKGLTALRALR--CLTISNTARQTFNLVMFDGLNKIFEAGLISLSLLFPFTVWGLSIFKGRLGTCNDGS-LGRADCYNEYSNSVFQWDI---------MSPRVYQQPY-LHLDSFASAFSSLYQIISLEGWVDLLENMMNSSGIGTPATVMGSAGNALFLVLFNFLSMVFILNLFVSFIVNNQARTTGSAYFTIEEKAWLESQKLLSQAKPKAIP----------------NLI-------ELSRVRQFFYQLAVEKKNFYYASFLQVVLYLHIIMLLSRSYNPGNLIGYQGVYFMFS-----TSVFLIQEALHMCGEGPRLYFRQKWNSIRLSIIIIAFIMNAVAFHVPASH---YWFHNIKGFFLLVIFLFIIPQNDTLTELLETAMASLPPILSLTYTWGVLFLVYAIALNQIFGLTRLGSNTTDNINFRTVIKSMIVLFRCSFGEGWNYIMADLTVSEPYCSSDDNSTYTDCGSETYAYLLLMSWNIISMYIFVNMFVSLIIGNFSYVYRSGGSRSGINRSEIKKYIEAWSKFDTDGTGELELSYL 1812

HSP 2 Score: 57.7658 bits (138), Expect = 1.474e-6
Identity = 65/278 (23.38%), Postives = 104/278 (37.41%), Query Frame = 2

Query:  512 ENKRP----HAYLRHFWGCFDTIMVICLWIS--ITIQTFELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCV-LQSANESDIKITDLAIPDSFCNPKFK----------------SGDSCPYSMKCVKIANSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWLVKNVFIAILTETFAEIRVQFQQ 1276
            EN+RP     A+ R  W   D +  +  W+   ++I++++    I+   PL   + L       G+ S LR              LK+ +PQ             + NV+  L++F   + ILGVQ F       CV     + +D    D+     + +P  K                 G  CP   KCV  AN      G   F     S   V+   S   +  +MY  MD   +     +FI  IF L   + N+ IA+L  +F     ++++
Sbjct:  478 ENQRPFGTPRAFARSSWNRIDLVSSVSFWLGMFLSIKSYDTKTGIRIFKPLAILRILRLVNVDTGMPSILRG-------------LKYGIPQ-------------LVNVSSMLVYFWIFFGILGVQIFQGSFRRQCVWFNPEDPTDTYQYDMQFCGGYLDPVTKRKQNYIYEDGSEGSVSKGFLCPQYSKCVSNANPY---NGRISFDNIVNSMELVFVIMSANTFTDLMYYTMDS-DEMAACLFFIVCIFVLTIWLLNLLIAVLVSSFEIANEEYKK 725

[Close]

BLAST of Voltage-dependent calcium channel vs. TrEMBL
Match: A0A4Z2CZB1 (Sodium leak channel non-selective protein isoform 2 OS=Schistosoma japonicum OX=6182 GN=EWB00_006269 PE=4 SV=1)

HSP 1 Score: 2162.88 bits (5603), Expect = 0.000e+0
Identity = 1116/1813 (61.56%), Postives = 1344/1813 (74.13%), Query Frame = 2

Query:  164 ERKTSHTRETQPTLPGVEFATDDAGDLTSVNWVYTTWARCAFKIXXXXXXXXXXXNTPETFKEYKWLFYVTYLLDIVVALLFTAEMFTKMKIKGIIRPSPYV----IVRHLFFVKVSNNIENKRPHAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDS----------------CKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWLVKNVFIAILTETFAEIRVQFQQMWSPKNQTDADSSKIFQTDGQRWKLVPVYESKPHGLAPKLFQEIVLKSTAFNVIIMLLVLANAIVAAGLHFNHDEL-------TQTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHC--MWYRTQLTYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEPKFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPNDWAQQLFSTFSGIYFILINLIFSFAFMSMFQILTQKGWVIVMHDTMDMAKHRGLNALVAIYFVFYHLFVTLIVLSLFVAVILDNLELEEDIKKLKQLKLREMSAETQQKLPMRLRIFEKFPNRPQMIKPARLLSDFLIPKIRDSFMRQFAQLPTL-------------------EEENESDEM-IAAAVSGVGV---SSLPRALSIE----IKRQIRGLKGNDKLNAIIYLINESNKTRMI--EQPIIYPTRSLLSTQHQIRTERRNLRNRMAATTMSINQKPRLNGEIRN-------MDFETNRKTEEAN---HFDIKILQQKAEQAEIKRNQQVDDLRENHPYFDKPLFTIGRESQFRQLCRMLVEAQYKPDINSENPEKQTFYKLQKFFGLVTYLDWVMIFVTTTSCISMAFETPTKRVMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTKLK-LSGDSPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVGRINVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVDQRRWLDLKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAIN--ENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRS-------KILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRENFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFIKAFYVRFLLRLIPKDRVGFDFTKKKDQQLFKEMCYEVELLRGGKDKEVSFHDVLTMLAYRSVDISKTXXXXXXXXXXXXXXXXXXXXXRQTIATWIERCIFRNRQKHGDLKFGLRESNEMVIPIFDDKKEGLGLDRSRKISS 5368
            ERK SH+R+TQ  + G++F  DD+ D TS  WVYT WA+  F+ AA++SLASVS NTP+TFK+   L Y+T++LD++VALLFT EM +KM I+G+  P+       ++R     K +   + KR  AY +  W  FD  M++C+W+S+ +Q  E    + C    D                 C     F + YG LS +R PRPLIL RV R+ L+ +LPQ RVKAI  RSTHQ+YNVTVFLLFFMSLY  LGVQFFGD++N+HCVL++ANE+ I   DLAIPDS+CNP  K  + CP +MKC++IA+SI+D+GGYAGF +FH S FTVYQAASQEGWVFIMYRAMDCL  WKGV YF+SMIF +AWLVKNVFIA+L ETFAEIRVQFQQMW+P++  DADSSKIFQ DG  WKLVPV+ES P GLAPK FQE +L+ST FNV+IM+LVLANAI AA LHFNH  L        Q +GFYYAE+ FTILFN+EAVFKIWCLGW +YW+RSL KFE  LC+GTT+HC  M YRT+ T+  VLRI RL+KASPMLEDFCFKIFG  +KLG LILFT+C L+ITS+ SLQLFC  Q++EP FDRF                                          STF              AFMSMFQILTQKGWV VMHDTMD+ ++  +   VAIYFVFYHL VTLIVLSLFVAVILDNLEL+EDIKKLKQLKLRE+SAETQQKLPMRLR+FE+FPNRPQMI+  RL+SDFL+PKIRDSFMRQFA +  L                   ++  E D++ +   + G      ++L    ++E    IKR++ GL G +K  AIIYL+NESNKTR++  E+      RSLLSTQHQIR ERRN RNR+    MS  +    NGE+R         D     +T   N   H DIK+LQQKA+ AEIKR QQ  +LRENHP+FD+PLF +GRES+FR+ C +LVEA++K   + ++ +   F  + KF GLVTY+DW+ IFVTT SC SM+ ETP  R+MNT E+++ EYIFFVAMT+EM  K+ ANG +FTP A+++DFGG LD FIYII +IFV+YMIRVD IG  SG  ILM+LRCLRPLRIFCLVP MRRVV+ELVRGFREILMVSVLLVVFMF FAVYGVH+FGG+LAICND   T K+ C+G F R+I+ TKLK + G+S   LVPRVWANPRNFNFDNIGNA+L LFEVLSLEGWVEIRDVIK R+G  +VIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVDQRRWLDLKGRI+LTQPL IPPRPK+ Q+    R   N +N   NS + + +K RC++YD+TQHI FKR SA +V+ NC  L+FP+N   E G++RS       +I  S  + +T  FCIEC LKI AL F GYWQSKRN +DM+V  L + W+ +H  ++      ++SNNFGW  ++LRFF+IAG+HVTLKMLM TV+MSM+KSLF+I++MFLLM+VYALAG+ILFGSVKYG+NLGRHANFHNTFR+ ALL RIVTGEDWNKIMHDCM+QPPFC     FW++DCGNF+A+LIYFCSFY++ITY+MLNVLVAIIMENFSLFYSNDEDAI+SYNDIRNFQ AWN +DVNRKG +KA+YVRFLLRLIP++RVGFD  KKKDQQLFKEMCYEVE LRGG+DK+VSFHDVL +LAYR+VDI+KTLQLEEL+AREELEYAIEEEVARQTIA WIERCIFRNRQKHG LKF +  + E  I    D  + +  +++ +I +
Sbjct:    5 ERKASHSRDTQGNIVGMDFTGDDSSDSTSKEWVYTRWAKIMFRTAAMISLASVSMNTPDTFKQVPVLMYITFILDLLVALLFTTEMISKMYIEGLFIPASSQNLNQLIRTQIAAKSAGGTDQKRNRAYFQKSWNYFDAFMLLCIWVSLALQCVEFYVTLGCSLKTDDESYNNTNKNLNKDYYLCPSNQEFRRNYGFLSIIRCPRPLILIRVFRAVLRLQLPQARVKAIFQRSTHQMYNVTVFLLFFMSLYGFLGVQFFGDELNYHCVLKTANETHITKQDLAIPDSYCNPAKKPDEQCPSNMKCIRIASSIQDDGGYAGFESFHISIFTVYQAASQEGWVFIMYRAMDCLASWKGVVYFMSMIFLVAWLVKNVFIAVLIETFAEIRVQFQQMWTPRHTADADSSKIFQFDGFTWKLVPVHESNPRGLAPKFFQETILRSTGFNVVIMVLVLANAITAAALHFNHQSLRDEDHLNDQLDGFYYAEIFFTILFNLEAVFKIWCLGWSNYWHRSLFKFELFLCVGTTIHCIPMIYRTEFTFLSVLRIVRLIKASPMLEDFCFKIFGPARKLGSLILFTTCFLVITSTFSLQLFCFFQVFEPTFDRF------------------------------------------STFPK------------AFMSMFQILTQKGWVAVMHDTMDVVENEAVTTGVAIYFVFYHLVVTLIVLSLFVAVILDNLELDEDIKKLKQLKLREISAETQQKLPMRLRVFERFPNRPQMIQLTRLVSDFLMPKIRDSFMRQFAAISALEEVEDEAIEEMLATMAKSTQQTIEHDQIKLMNPLYGKPTYLNATLNNHTNVEALRTIKRKVHGLHGEEKFRAIIYLLNESNKTRLLTSEKASNVGNRSLLSTQHQIRLERRNTRNRV-GNQMSSQKSFGANGEVRGGNPSGRAGDHNAESQTTTGNRTSHDDIKLLQQKAQLAEIKRIQQEVELRENHPFFDRPLFVLGRESRFRRFCLILVEARHKAHDSMDSTDNGNF--IHKFLGLVTYMDWIAIFVTTLSCASMSLETPHFRLMNTPEVQICEYIFFVAMTLEMTFKIFANGLVFTPNALLKDFGGFLDLFIYIISLIFVSYMIRVDVIGPASGGHILMVLRCLRPLRIFCLVPQMRRVVYELVRGFREILMVSVLLVVFMFIFAVYGVHLFGGRLAICNDRNITSKEKCIGRFMREIASTKLKSVKGESIKILVPRVWANPRNFNFDNIGNAILALFEVLSLEGWVEIRDVIKERIGPRHVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVDQRRWLDLKGRIRLTQPLQIPPRPKLHQEPGLER---NIVNPKSNSLEKKSLKFRCFIYDITQHILFKRASATLVVANCFLLFFPFN---ELGIERSSWVRPRYQIQVSLGIIFTLFFCIECLLKIIALKFTGYWQSKRNRFDMLVAVLGVTWIILHFILRPIPEKHMISNNFGWFVLMLRFFTIAGRHVTLKMLMLTVVMSMYKSLFIIMSMFLLMMVYALAGVILFGSVKYGDNLGRHANFHNTFRATALLTRIVTGEDWNKIMHDCMIQPPFCRMHATFWETDCGNFRAALIYFCSFYVIITYVMLNVLVAIIMENFSLFYSNDEDAIMSYNDIRNFQLAWNIVDVNRKGVVKAYYVRFLLRLIPRERVGFDLAKKKDQQLFKEMCYEVETLRGGRDKDVSFHDVLMVLAYRTVDITKTLQLEELIAREELEYAIEEEVARQTIAAWIERCIFRNRQKHGQLKFKMHANIERQISTALDDSDEVSKNKNVRIKN 1754

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BLAST of Voltage-dependent calcium channel vs. TrEMBL
Match: A0A4S2LXR2 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_004142 PE=4 SV=1)

HSP 1 Score: 2160.57 bits (5597), Expect = 0.000e+0
Identity = 1135/1898 (59.80%), Postives = 1380/1898 (72.71%), Query Frame = 2

Query:  164 ERKTSHTRETQPTLPGVEFATDDAGDLTSVNWVYTTWARCAFKIXXXXXXXXXXXNTPETFKEYKWLFYVTYLLDIVVALLFTAEMFTKMKIKGIIRPSPYVIVRHLFFVKVSNNI-----ENKRPHAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDS---CPYSMKCVKIANSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWLVKNVFIAILTETFAEIRVQFQQMWSPKNQTDADSSKIFQTDGQRWKLVPVYESKPHGLAPKLFQEIVLKSTAFNVIIMLLVLANAIVAAGLHFNHD--------ELTQTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHCM--WYRTQLTYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEPKFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPNDWAQQLFSTFSGIYFILINLIFSFAFMSMFQILTQKGWVIVMHDTMDMAKHRGLNALVAIYFVFYHLFVTLIVLSLFVAVILDNLELEEDIKKLKQLKLREMSAETQQKLPMRLRIFEKFPNRPQMIKPARLLSDFLIPKIRDSFMRQFAQLPTLE------------------EENESDEMIAAAVSGVGVSSLPRALSIE----IKRQIRGLKGNDKLNAIIYLINESNKTRMI--EQPIIYPTRSLLSTQHQIRTERRNLRNRMAATTMSINQKPRLNGEIRNMDFETNRKTEEA--------NHFDIKILQQKAEQAEIKRNQQVDDLRENHPYFDKPLFTIGRESQFRQLCRMLVEAQYKPDINSENPEKQTFYKLQKFFGLVTYLDWVMIFVTTTSCISMAFETPTKRVMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTKLK-LSGDSPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVGRINVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVDQRRWLDLKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNN----DDEYGMKRSKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRENFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFIKAFYVRFLLRLIPKDRVGFDFTKKKDQQLFKEMCYEVELLRGGKDKEVSFHDVLTMLAYRSVDISKTXXXXXXXXXXXXXXXXXXXXXRQTIATWIERCIFRNRQKHGDLKFGLRESNEMVIPIFDDKKEGL--GLDRSRKISSGAYQTKFLSLPTLDGRQNTSDGSLPSSGITIGRLNDHLKNQPM----------GFKRRRSVKKNSSTNQTLTEVSEDELNDE-LND-IVPTQD---PDLTPNQLPS 5641
            ERK SH+R+TQ  L G++FA DD  D  S  W+Y+ WA+   ++AAL+SL SVS NTP TFKE   L YVT +LD  VAL+FT EM +KM I+G+   +    +  L   ++++ +     + KR  +Y + FW CFD  M++C++ S+ +Q  E    ++C     SC     FW+KYG L+ +R PRPLIL RV R+ L+ +LP+ RVKAI  RSTHQ YNVT+FLLFFMSLY  LGVQFFGD++N+HCV+++ANES+I   DLAIPD++C+P     D+   CP  MKCV+I  SIED+GGYAGF +FH S FTVYQAASQEGWVFIMYRAMDCL  WKGV YF+SMIFF+AWLVKNVFIA+L ETFAEIRVQFQQMWSP++  DADSSK+FQ DG  WKLVPV+E+KP GLAP+ FQEIVLKST FNV+IM+LVLANAI AA LHFNH+         L+Q +GFYYAELVFT LFN+EAVFKIWCLGW SYWYRSL KFE  LC+GTT+HC+   YRT+ TY  VLR  RL+KASPMLEDFCFKIFG  KKLG LILFT+C L+ITS+ SLQL             FS+F                     +AM        D +   FSTF              AF SMFQILTQKGWV VMHDTMD+  +RG+   VA+YFVFYHL VTLIVLSLFVAVILDNLEL+EDIKKLKQLKLRE+SAETQQKLP+RLR+FEKFPNRPQMI+  RL+SDFL+PKIRDSFMRQFA +  LE                  +  E    +A+ + G      P +  +E    IKR++ GL G +K+ AIIYL+NESNKTR++  EQ     TRSLLSTQHQIR +RR++R+R     +S ++  R NGEIR      + +  E+        +  DIK+LQQKA+ AEIKR QQ  +LRENHP+FD+PLF +GR+++ R LC ++VEA++K   +S++ +  + +   K  G V YLDW  I VT  SC SM+ ETP  R+MNT ++++ EYIFFVAMTIEMALK+LANG +FTPKA+++DFGG LDFF YII +IFV+YM+RV+TIG  SG+ ILM+LRCLRPLRIFCLVP MRRVV+ELVRGFREILMVSVLLVVFMF FAVYGVH+FGG+LAICND   T K+ CVG F R+ISVTKLK + G  P  LVPRVWANPRNFNFDNIGNAML LFEVLSLEGWVEIRDVI  R+G  + IYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVDQRRWLDLKGRIKLTQPL +PPRPK+RQ+  Q+    N +  N+ + + +K RC +YD+TQHI FKR SAI+V+ NC  L+FP+N      D    KR     S  + +T  FC+EC LKI AL F GYWQS+RN +DM+V  L   W+ +H  ++ N +   +SN+FGW  ++LRFF+IAG+HVTLKMLM TV+MSM+KSLF+I +MFLLM+VYALAG+ LFGSVKYG+NLGRHANFHN FR+ ALL RIVTGEDWNKIMHDCM+QPPFC  R NFW++DCGNF+A+LIYFCSFY++ITY+MLNVLVAIIMENFSLFYSNDEDAI+SY+DIRNFQ AWN IDVNRKG IKA YVRFLLRLIP++RVGFD +KKKDQQLFKEMCYEVE LRGG+DK+VSFHDVL +LAYR+VDI+KTLQLEEL+AREELEYAIEEEVARQTIA WIERCIFRNRQKHG L F + ++ +  + +  D+ +G      R ++I+    +   +S  TL  R+ +S       G +  R   H+ N PM          G + R+SV  N      L E  E EL+ E L +  +P Q    P +T  + P+
Sbjct:    6 ERKFSHSRDTQGNLIGLDFAADDGPDSISREWIYSRWAKIIMRVAALVSLISVSMNTPATFKEVPSLMYVTLILDCAVALVFTVEMVSKMFIEGLFVSTTSQNLNQLIRTQIASKVAGGGHDAKRKKSYFQRFWNCFDATMLLCIYASLGLQGVEFYITMQCPAGQMSCHVSEDFWRKYGSLAIIRCPRPLILIRVFRAVLRLQLPKARVKAIFQRSTHQTYNVTMFLLFFMSLYGFLGVQFFGDNLNYHCVVKTANESNITKHDLAIPDAYCDPTGDRKDADKQCPRDMKCVRIVTSIEDDGGYAGFESFHISIFTVYQAASQEGWVFIMYRAMDCLAPWKGVIYFLSMIFFVAWLVKNVFIAVLIETFAEIRVQFQQMWSPRHTADADSSKVFQADGLTWKLVPVHENKPKGLAPRFFQEIVLKSTGFNVVIMVLVLANAITAAALHFNHNTIRDPSASHLSQLDGFYYAELVFTALFNLEAVFKIWCLGWSSYWYRSLFKFELFLCVGTTIHCIPVLYRTEFTYLAVLRTVRLIKASPMLEDFCFKIFGPAKKLGSLILFTTCFLVITSTFSLQL-------------FSSF---------------------QAM--------DSSFDRFSTFPK------------AFASMFQILTQKGWVAVMHDTMDVVTNRGVITGVAVYFVFYHLVVTLIVLSLFVAVILDNLELDEDIKKLKQLKLREISAETQQKLPLRLRVFEKFPNRPQMIQLTRLVSDFLMPKIRDSFMRQFAAVSALEEVEDETIEEMLSSMTRQMQPIEPRRSVASRIKGF-FEPAPSSAQLETIRAIKRKVHGLHGQEKVRAIIYLLNESNKTRLLNTEQASSTGTRSLLSTQHQIRLDRRSMRHR-NGNALSASKSYRANGEIRTTAGRADTREHESRTKSGDGSSRVDIKLLQQKAQMAEIKRTQQEVELRENHPFFDRPLFALGRDNRLRHLCLLVVEARHKGGESSDSSDNGSAF--HKLLGHVPYLDWAAIIVTILSCASMSVETPQARLMNTPKVQICEYIFFVAMTIEMALKILANGLLFTPKALLKDFGGFLDFFNYIISLIFVSYMMRVETIGPESGEHILMVLRCLRPLRIFCLVPQMRRVVYELVRGFREILMVSVLLVVFMFIFAVYGVHLFGGRLAICNDREITTKEKCVGRFHREISVTKLKSIKGPGPRLLVPRVWANPRNFNFDNIGNAMLALFEVLSLEGWVEIRDVINERIGPRHTIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVDQRRWLDLKGRIKLTQPLQLPPRPKLRQEPGQDGYSANLMT-NNLEKKSVKFRCLIYDITQHIAFKRASAILVVANCGLLFFPFNEVDLERDSNVHKRYLAQVSLGIIFTLFFCLECLLKIIALGFKGYWQSRRNRFDMLVAILGCTWIILHFILRPNPDYHWISNSFGWSVLILRFFTIAGRHVTLKMLMLTVIMSMYKSLFIITSMFLLMIVYALAGVTLFGSVKYGDNLGRHANFHNAFRATALLTRIVTGEDWNKIMHDCMIQPPFCRMRPNFWETDCGNFRAALIYFCSFYVIITYVMLNVLVAIIMENFSLFYSNDEDAIMSYSDIRNFQLAWNVIDVNRKGMIKASYVRFLLRLIPRERVGFDLSKKKDQQLFKEMCYEVETLRGGRDKDVSFHDVLMVLAYRTVDITKTLQLEELIAREELEYAIEEEVARQTIAAWIERCIFRNRQKHGHLNFKMHQTADRQMSLSVDETDGTDGASQRVQQITPTGKKASVIS-NTLKTRRESSRAMEQPYGASNERA--HMINAPMLTPTATLQHSGRRLRKSVSTNKDECLALLEAEEGELDMEPLGEYAIPPQSLTTPQVTTEKQPN 1841

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BLAST of Voltage-dependent calcium channel vs. TrEMBL
Match: A0A4Z2CZ74 (Sodium leak channel non-selective protein isoform 1 OS=Schistosoma japonicum OX=6182 GN=EWB00_006269 PE=4 SV=1)

HSP 1 Score: 2157.49 bits (5589), Expect = 0.000e+0
Identity = 1118/1830 (61.09%), Postives = 1341/1830 (73.28%), Query Frame = 2

Query:  164 ERKTSHTRETQPTLPGVEFATDDAGDLTSVNWVYTTWARCAFKIXXXXXXXXXXXNTPETFKEYKWLFYVTYLLDIVVALLFTAEMFTKMKIKGIIRPSPYV----IVRHLFFVKVSNNIENKRPHAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDS----------------CKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWLVKNVFIAILTETFAEIRVQFQQMWSPKNQTDADSSKIFQTDGQRWKLVPVYESKPHGLAPKLFQEIVLKSTAFNVIIMLLVLANAIVAAGLHFNHDEL-------TQTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHC--MWYRTQLTYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEPKFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPNDWAQQLFSTFSGIYFILINLIFSFAFMSMFQILTQKGWVIVMHDTMDMAKHRGLNALVAIYFVFYHLFVTLIVLSLFVAVILDNLELEEDIKKLKQLKLREMSAETQQKLPMRLRIFEKFPNRPQMIKPARLLSDFLIPKIRDSFMRQFAQLP-----------------------TLEEE-------------------NESDEMIAAAV--SGVGVSSLPRALSIEIKRQIRGLKGNDKLNAIIYLINESNKTRMI--EQPIIYPTRSLLSTQHQIRTERRNLRNRMAATTMSINQKPRLNGEIRNM-------DFETNRKTEEAN---HFDIKILQQKAEQAEIKRNQQVDDLRENHPYFDKPLFTIGRESQFRQLCRMLVEAQYKPDINSENPEKQTFYKLQKFFGLVTYLDWVMIFVTTTSCISMAFETPTKRVMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTKLK-LSGDSPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVGRINVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVDQRRWLDLKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAIN--ENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRS-------KILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRENFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFIKAFYVRFLLRLIPKDRVGFDFTKKKDQQLFKEMCYEVELLRGGKDKEVSFHDVLTMLAYRSVDISKTXXXXXXXXXXXXXXXXXXXXXRQTIATWIERCIFRNRQKHGDLKFGLRESNEMVIPIFDDKKEGLGLDRSRKISS 5368
            ERK SH+R+TQ  + G++F  DD+ D TS  WVYT WA+  F+ AA++SLASVS NTP+TFK+   L Y+T++LD++VALLFT EM +KM I+G+  P+       ++R     K +   + KR  AY +  W  FD  M++C+W+S+ +Q  E    + C    D                 C     F + YG LS +R PRPLIL RV R+ L+ +LPQ RVKAI  RSTHQ+YNVTVFLLFFMSLY  LGVQFFGD++N+HCVL++ANE+ I   DLAIPDS+CNP  K  + CP +MKC++IA+SI+D+GGYAGF +FH S FTVYQAASQEGWVFIMYRAMDCL  WKGV YF+SMIF +AWLVKNVFIA+L ETFAEIRVQFQQMW+P++  DADSSKIFQ DG  WKLVPV+ES P GLAPK FQE +L+ST FNV+IM+LVLANAI AA LHFNH  L        Q +GFYYAE+ FTILFN+EAVFKIWCLGW +YW+RSL KFE  LC+GTT+HC  M YRT+ T+  VLRI RL+KASPMLEDFCFKIFG  +KLG LILFT+C L+ITS+ SLQLFC  Q++EP FDRF                                          STF              AFMSMFQILTQKGWV VMHDTMD+ ++  +   VAIYFVFYHL VTLIVLSLFVAVILDNLEL+EDIKKLKQLKLRE+SAETQQKLPMRLR+FE+FPNRPQMI+  RL+SDFL+PKIRDSFMRQFA +                        T+E +                   N+ D M+      S   V +L       IKR++ GL G +K  AIIYL+NESNKTR++  E+      RSLLSTQHQIR ERRN RNR+    MS  +    NGE+R         D     +T   N   H DIK+LQQKA+ AEIKR QQ  +LRENHP+FD+PLF +GRES+FR+ C +LVEA++K   + ++ +   F  + KF GLVTY+DW+ IFVTT SC SM+ ETP  R+MNT E+++ EYIFFVAMT+EM  K+ ANG +FTP A+++DFGG LD FIYII +IFV+YMIRVD IG  SG  ILM+LRCLRPLRIFCLVP MRRVV+ELVRGFREILMVSVLLVVFMF FAVYGVH+FGG+LAICND   T K+ C+G F R+I+ TKLK + G+S   LVPRVWANPRNFNFDNIGNA+L LFEVLSLEGWVEIRDVIK R+G  +VIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVDQRRWLDLKGRI+LTQPL IPPRPK+ Q+    R   N +N   NS + + +K RC++YD+TQHI FKR SA +V+ NC  L+FP+N   E G++RS       +I  S  + +T  FCIEC LKI AL F GYWQSKRN +DM+V  L + W+ +H  ++      ++SNNFGW  ++LRFF+IAG+HVTLKMLM TV+MSM+KSLF+I++MFLLM+VYALAG+ILFGSVKYG+NLGRHANFHNTFR+ ALL RIVTGEDWNKIMHDCM+QPPFC     FW++DCGNF+A+LIYFCSFY++ITY+MLNVLVAIIMENFSLFYSNDEDAI+SYNDIRNFQ AWN +DVNRKG +KA+YVRFLLRLIP++RVGFD  KKKDQQLFKEMCYEVE LRGG+DK+VSFHDVL +LAYR+VDI+KTLQLEEL+AREELEYAIEEEVARQTIA WIERCIFRNRQKHG LKF +  + E  I    D  + +  +++ +I +
Sbjct:    5 ERKASHSRDTQGNIVGMDFTGDDSSDSTSKEWVYTRWAKIMFRTAAMISLASVSMNTPDTFKQVPVLMYITFILDLLVALLFTTEMISKMYIEGLFIPASSQNLNQLIRTQIAAKSAGGTDQKRNRAYFQKSWNYFDAFMLLCIWVSLALQCVEFYVTLGCSLKTDDESYNNTNKNLNKDYYLCPSNQEFRRNYGFLSIIRCPRPLILIRVFRAVLRLQLPQARVKAIFQRSTHQMYNVTVFLLFFMSLYGFLGVQFFGDELNYHCVLKTANETHITKQDLAIPDSYCNPAKKPDEQCPSNMKCIRIASSIQDDGGYAGFESFHISIFTVYQAASQEGWVFIMYRAMDCLASWKGVVYFMSMIFLVAWLVKNVFIAVLIETFAEIRVQFQQMWTPRHTADADSSKIFQFDGFTWKLVPVHESNPRGLAPKFFQETILRSTGFNVVIMVLVLANAITAAALHFNHQSLRDEDHLNDQLDGFYYAEIFFTILFNLEAVFKIWCLGWSNYWHRSLFKFELFLCVGTTIHCIPMIYRTEFTFLSVLRIVRLIKASPMLEDFCFKIFGPARKLGSLILFTTCFLVITSTFSLQLFCFFQVFEPTFDRF------------------------------------------STFPK------------AFMSMFQILTQKGWVAVMHDTMDVVENEAVTTGVAIYFVFYHLVVTLIVLSLFVAVILDNLELDEDIKKLKQLKLREISAETQQKLPMRLRVFERFPNRPQMIQLTRLVSDFLMPKIRDSFMRQFAAISALEEVEDEAIEEMLATMAKSTQQTIEHDQIKLMNPLYGKPTYLNATLNKYDNMLTKETLHSHTNVEALR-----TIKRKVHGLHGEEKFRAIIYLLNESNKTRLLTSEKASNVGNRSLLSTQHQIRLERRNTRNRVG-NQMSSQKSFGANGEVRGGNPSGRAGDHNAESQTTTGNRTSHDDIKLLQQKAQLAEIKRIQQEVELRENHPFFDRPLFVLGRESRFRRFCLILVEARHKAHDSMDSTDNGNF--IHKFLGLVTYMDWIAIFVTTLSCASMSLETPHFRLMNTPEVQICEYIFFVAMTLEMTFKIFANGLVFTPNALLKDFGGFLDLFIYIISLIFVSYMIRVDVIGPASGGHILMVLRCLRPLRIFCLVPQMRRVVYELVRGFREILMVSVLLVVFMFIFAVYGVHLFGGRLAICNDRNITSKEKCIGRFMREIASTKLKSVKGESIKILVPRVWANPRNFNFDNIGNAILALFEVLSLEGWVEIRDVIKERIGPRHVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVDQRRWLDLKGRIRLTQPLQIPPRPKLHQEPGLER---NIVNPKSNSLEKKSLKFRCFIYDITQHILFKRASATLVVANCFLLFFPFN---ELGIERSSWVRPRYQIQVSLGIIFTLFFCIECLLKIIALKFTGYWQSKRNRFDMLVAVLGVTWIILHFILRPIPEKHMISNNFGWFVLMLRFFTIAGRHVTLKMLMLTVVMSMYKSLFIIMSMFLLMMVYALAGVILFGSVKYGDNLGRHANFHNTFRATALLTRIVTGEDWNKIMHDCMIQPPFCRMHATFWETDCGNFRAALIYFCSFYVIITYVMLNVLVAIIMENFSLFYSNDEDAIMSYNDIRNFQLAWNIVDVNRKGVVKAYYVRFLLRLIPRERVGFDLAKKKDQQLFKEMCYEVETLRGGRDKDVSFHDVLMVLAYRTVDITKTLQLEELIAREELEYAIEEEVARQTIAAWIERCIFRNRQKHGQLKFKMHANIERQISTALDDSDEVSKNKNVRIKN 1766

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BLAST of Voltage-dependent calcium channel vs. TrEMBL
Match: A0A4S2LXR3 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_004142 PE=4 SV=1)

HSP 1 Score: 2157.1 bits (5588), Expect = 0.000e+0
Identity = 1136/1898 (59.85%), Postives = 1377/1898 (72.55%), Query Frame = 2

Query:  164 ERKTSHTRETQPTLPGVEFATDDAGDLTSVNWVYTTWARCAFKIXXXXXXXXXXXNTPETFKEYKWLFYVTYLLDIVVALLFTAEMFTKMKIKGIIRPSPYVIVRHLFFVKVSNNI-----ENKRPHAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDS---CPYSMKCVKIANSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWLVKNVFIAILTETFAEIRVQFQQMWSPKNQTDADSSKIFQTDGQRWKLVPVYESKPHGLAPKLFQEIVLKSTAFNVIIMLLVLANAIVAAGLHFNHD--------ELTQTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHCM--WYRTQLTYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEPKFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPNDWAQQLFSTFSGIYFILINLIFSFAFMSMFQILTQKGWVIVMHDTMDMAKHRGLNALVAIYFVFYHLFVTLIVLSLFVAVILDNLELEEDIKKLKQLKLREMSAETQQKLPMRLRIFEKFPNRPQMIKPARLLSDFLIPKIRDSFMRQFAQLPTLE------------------EENESDEMIAAAVSGVGVSSLPRALSIE----IKRQIRGLKGNDKLNAIIYLINESNKTRMI--EQPIIYPTRSLLSTQHQIRTERRNLRNRMAATTMSINQKPRLNGEIRNMDFETNRKTEEA--------NHFDIKILQQKAEQAEIKRNQQVDDLRENHPYFDKPLFTIGRESQFRQLCRMLVEAQYKPDINSENPEKQTFYKLQKFFGLVTYLDWVMIFVTTTSCISMAFETPTKRVMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTKLK-LSGDSPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVGRINVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVDQRRWLDLKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNN----DDEYGMKRSKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRENFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFIKAFYVRFLLRLIPKDRVGFDFTKKKDQQLFKEMCYEVELLRGGKDKEVSFHDVLTMLAYRSVDISKTXXXXXXXXXXXXXXXXXXXXXRQTIATWIERCIFRNRQKHGDLKFGLRESNEMVIPIFDDKKEGL--GLDRSRKISSGAYQTKFLSLPTLDGRQNTSDGSLPSSGITIGRLNDHLKNQPM----------GFKRRRSVKKNSSTNQTLTEVSEDELNDE-LND-IVPTQD---PDLTPNQLPS 5641
            ERK SH+R+TQ  L G++FA DD  D  S  W+Y+ WA+   ++AAL+SL SVS NTP TFKE   L YVT +LD  VAL+FT EM +KM I+G+             FV  ++ +     + KR  +Y + FW CFD  M++C++ S+ +Q  E    ++C     SC     FW+KYG L+ +R PRPLIL RV R+ L+ +LP+ RVKAI  RSTHQ YNVT+FLLFFMSLY  LGVQFFGD++N+HCV+++ANES+I   DLAIPD++C+P     D+   CP  MKCV+I  SIED+GGYAGF +FH S FTVYQAASQEGWVFIMYRAMDCL  WKGV YF+SMIFF+AWLVKNVFIA+L ETFAEIRVQFQQMWSP++  DADSSK+FQ DG  WKLVPV+E+KP GLAP+ FQEIVLKST FNV+IM+LVLANAI AA LHFNH+         L+Q +GFYYAELVFT LFN+EAVFKIWCLGW SYWYRSL KFE  LC+GTT+HC+   YRT+ TY  VLR  RL+KASPMLEDFCFKIFG  KKLG LILFT+C L+ITS+ SLQL             FS+F                     +AM        D +   FSTF              AF SMFQILTQKGWV VMHDTMD+  +RG+   VA+YFVFYHL VTLIVLSLFVAVILDNLEL+EDIKKLKQLKLRE+SAETQQKLP+RLR+FEKFPNRPQMI+  RL+SDFL+PKIRDSFMRQFA +  LE                  +  E    +A+ + G      P +  +E    IKR++ GL G +K+ AIIYL+NESNKTR++  EQ     TRSLLSTQHQIR +RR++R+R     +S ++  R NGEIR      + +  E+        +  DIK+LQQKA+ AEIKR QQ  +LRENHP+FD+PLF +GR+++ R LC ++VEA++K   +S++ +  + +   K  G V YLDW  I VT  SC SM+ ETP  R+MNT ++++ EYIFFVAMTIEMALK+LANG +FTPKA+++DFGG LDFF YII +IFV+YM+RV+TIG  SG+ ILM+LRCLRPLRIFCLVP MRRVV+ELVRGFREILMVSVLLVVFMF FAVYGVH+FGG+LAICND   T K+ CVG F R+ISVTKLK + G  P  LVPRVWANPRNFNFDNIGNAML LFEVLSLEGWVEIRDVI  R+G  + IYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVDQRRWLDLKGRIKLTQPL +PPRPK+RQ+  Q+    N +  N+ + + +K RC +YD+TQHI FKR SAI+V+ NC  L+FP+N      D    KR     S  + +T  FC+EC LKI AL F GYWQS+RN +DM+V  L   W+ +H  ++ N +   +SN+FGW  ++LRFF+IAG+HVTLKMLM TV+MSM+KSLF+I +MFLLM+VYALAG+ LFGSVKYG+NLGRHANFHN FR+ ALL RIVTGEDWNKIMHDCM+QPPFC  R NFW++DCGNF+A+LIYFCSFY++ITY+MLNVLVAIIMENFSLFYSNDEDAI+SY+DIRNFQ AWN IDVNRKG IKA YVRFLLRLIP++RVGFD +KKKDQQLFKEMCYEVE LRGG+DK+VSFHDVL +LAYR+VDI+KTLQLEEL+AREELEYAIEEEVARQTIA WIERCIFRNRQKHG L F + ++ +  + +  D+ +G      R ++I+    +   +S  TL  R+ +S       G +  R   H+ N PM          G + R+SV  N      L E  E EL+ E L +  +P Q    P +T  + P+
Sbjct:    6 ERKFSHSRDTQGNLIGLDFAADDGPDSISREWIYSRWAKIIMRVAALVSLISVSMNTPATFKEVPSLMYVTLILDCAVALVFTVEMVSKMFIEGL-------------FVSTTSQVAGGGHDAKRKKSYFQRFWNCFDATMLLCIYASLGLQGVEFYITMQCPAGQMSCHVSEDFWRKYGSLAIIRCPRPLILIRVFRAVLRLQLPKARVKAIFQRSTHQTYNVTMFLLFFMSLYGFLGVQFFGDNLNYHCVVKTANESNITKHDLAIPDAYCDPTGDRKDADKQCPRDMKCVRIVTSIEDDGGYAGFESFHISIFTVYQAASQEGWVFIMYRAMDCLAPWKGVIYFLSMIFFVAWLVKNVFIAVLIETFAEIRVQFQQMWSPRHTADADSSKVFQADGLTWKLVPVHENKPKGLAPRFFQEIVLKSTGFNVVIMVLVLANAITAAALHFNHNTIRDPSASHLSQLDGFYYAELVFTALFNLEAVFKIWCLGWSSYWYRSLFKFELFLCVGTTIHCIPVLYRTEFTYLAVLRTVRLIKASPMLEDFCFKIFGPAKKLGSLILFTTCFLVITSTFSLQL-------------FSSF---------------------QAM--------DSSFDRFSTFPK------------AFASMFQILTQKGWVAVMHDTMDVVTNRGVITGVAVYFVFYHLVVTLIVLSLFVAVILDNLELDEDIKKLKQLKLREISAETQQKLPLRLRVFEKFPNRPQMIQLTRLVSDFLMPKIRDSFMRQFAAVSALEEVEDETIEEMLSSMTRQMQPIEPRRSVASRIKGF-FEPAPSSAQLETIRAIKRKVHGLHGQEKVRAIIYLLNESNKTRLLNTEQASSTGTRSLLSTQHQIRLDRRSMRHR-NGNALSASKSYRANGEIRTTAGRADTREHESRTKSGDGSSRVDIKLLQQKAQMAEIKRTQQEVELRENHPFFDRPLFALGRDNRLRHLCLLVVEARHKGGESSDSSDNGSAF--HKLLGHVPYLDWAAIIVTILSCASMSVETPQARLMNTPKVQICEYIFFVAMTIEMALKILANGLLFTPKALLKDFGGFLDFFNYIISLIFVSYMMRVETIGPESGEHILMVLRCLRPLRIFCLVPQMRRVVYELVRGFREILMVSVLLVVFMFIFAVYGVHLFGGRLAICNDREITTKEKCVGRFHREISVTKLKSIKGPGPRLLVPRVWANPRNFNFDNIGNAMLALFEVLSLEGWVEIRDVINERIGPRHTIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVDQRRWLDLKGRIKLTQPLQLPPRPKLRQEPGQDGYSANLMT-NNLEKKSVKFRCLIYDITQHIAFKRASAILVVANCGLLFFPFNEVDLERDSNVHKRYLAQVSLGIIFTLFFCLECLLKIIALGFKGYWQSRRNRFDMLVAILGCTWIILHFILRPNPDYHWISNSFGWSVLILRFFTIAGRHVTLKMLMLTVIMSMYKSLFIITSMFLLMIVYALAGVTLFGSVKYGDNLGRHANFHNAFRATALLTRIVTGEDWNKIMHDCMIQPPFCRMRPNFWETDCGNFRAALIYFCSFYVIITYVMLNVLVAIIMENFSLFYSNDEDAIMSYSDIRNFQLAWNVIDVNRKGMIKASYVRFLLRLIPRERVGFDLSKKKDQQLFKEMCYEVETLRGGRDKDVSFHDVLMVLAYRTVDITKTLQLEELIAREELEYAIEEEVARQTIAAWIERCIFRNRQKHGHLNFKMHQTADRQMSLSVDETDGTDGASQRVQQITPTGKKASVIS-NTLKTRRESSRAMEQPYGASNERA--HMINAPMLTPTATLQHSGRRLRKSVSTNKDECLALLEAEEGELDMEPLGEYAIPPQSLTTPQVTTEKQPN 1828

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BLAST of Voltage-dependent calcium channel vs. TrEMBL
Match: G4VG52 (Voltage-dependent calcium channel OS=Schistosoma mansoni OX=6183 GN=Smp_197640 PE=4 SV=1)

HSP 1 Score: 2153.64 bits (5579), Expect = 0.000e+0
Identity = 1119/1827 (61.25%), Postives = 1344/1827 (73.56%), Query Frame = 2

Query:  152 MHRSERKTSHTRETQPTLPGVEFATDDAGDLTSVNWVYTTWARCAFKIXXXXXXXXXXXNTPETFKEYKWLFYVTYLLDIVVALLFTAEMFTKMKIKGIIRPSPYVIVRHLFFVKVSNNIENKRPHAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDS------------------CKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWLVKNVFIAILTETFAEIRVQFQQMWSPKNQTDADSSKIFQTDGQRWKLVPVYESKPHGLAPKLFQEIVLKSTAFNVIIMLLVLANAIVAAGLHFNHDEL-------TQTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHCM--WYRTQLTYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEPKFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPNDWAQQLFSTFSGIYFILINLIFSFAFMSMFQILTQKGWVIVMHDTMDMAKHRGLNALVAIYFVFYHLFVTLIVLSLFVAVILDNLELEEDIKKLKQLKLREMSAETQQKLPMRLRIFEKFPNRPQMIKPARLLSDFLIPKIRDSFMRQFA---------------QLPTLEEENESDEMIAAAVSGVGVS-----------------SLPRALSIE----IKRQIRGLKGNDKLNAIIYLINESNKTRM--IEQPIIYPTRSLLSTQHQIRTERRNLRNRMAATTMSINQKPRLNGEIRNMD------FETNRKTEEAN---HFDIKILQQKAEQAEIKRNQQVDDLRENHPYFDKPLFTIGRESQFRQLCRMLVEAQYKPDINSENPEKQTFYKLQKFFGLVTYLDWVMIFVTTTSCISMAFETPTKRVMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTKLK-LSGDSPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVGRINVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVDQRRWLDLKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRS-------KILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRENFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFIKAFYVRFLLRLIPKDRVGFDFTKKKDQQLFKEMCYEVELLRGGKDKEVSFHDVLTMLAYRSVDISKTXXXXXXXXXXXXXXXXXXXXXRQTIATWIERCIFRNRQKHGDLKFGLRESNEMVIP-IFDD-----KKEGLGLDRSRKISS 5368
            M  SERK SH+R+TQ  + G++F+ DD  D TS  WVYT WA+   + AA++SLASVS NTP+TFK+   L Y+T++LD++VALLFT EM +KM I+G+  P+           + S  I+ KR  AY +  W  FD  M+ C+W S+ +Q  E     +C  PL S                  C     F + YG LS +R PRPLIL RV R+ L+ +LPQ RVKAI  RSTHQVYNVTVFLLFFMSLY  LGVQFFGD++N+HCVL++ANE+ I   DLAIPDS+CNP       CP +MKC++IA+SI+D+GGYAGF +F+ S FTVYQAASQEGWVFIMYRAMDCL  WKGV YF+SMIF +AWLVKNVFIA+L ETFAEIRVQFQQMW+P++  DADSSKIFQ DG  WKLVPV+ES P GLAPK FQE +L+ST FNV+IM+LVLANAI AA LHFNH  L        Q +GFYYAE++FTILFN EAVFKIWCLGW +YW+RSL KFE  LC+GTT+HC+   YRT+ T+  VLRI RL+KASPMLEDFCFKIFG  KKLG LILFT+C LIITS+ SLQLFC  Q++EP FDR                                          FSTF              AFMSMFQILTQKGWV VMHDTMD+ ++  +   VAIYFVFYHL VTLIVLSLFVAVILDNLEL+EDIKKLKQLKLRE+SAETQQKLPMRLR+FEKFPNRPQM++  RL+SDFL+PKIRDSFMRQFA                L T+ +  ++ E     ++ + ++                 +LP    +E    IKR++ GL G +K  AIIYL+NESNKTR+  IE+      RSLLSTQHQIR +RR+ RNR+    +  N+  R NGE+R  +           +T   N   H DIK+LQQKA+ AE+KR QQ  +LRENHP+FD+PLF +GRE++FR+LC +LVEA++K + + ++ +   F  + KF GLVTYLDW+ IFVTT SC SM+ ETP  R+MNT E+++ EYIFFV MT+EM LK+ ANG IFTP A+++DFGG LD FIYII +IFV+YM+RVD IG GS   +LM+LRCLRPLRIFCLVP MRRVV+ELVRGFREILMVSVLLVVFMF FAVYGVH+FGG+LAICND +   K+ CVG F R+++ TKLK + G+S   LVPRVWANPRNFNFDNIGNA+L LFEVLSLEGWVEIRDVIK R+G  +VIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVDQRRWLDLKGRI+LTQPL IPPRPK+ Q+    R   N    N+ + + +K RC++YD+TQHI FKR SA +V+ NC  L+FP+N   E G +RS       +I  S  + +T  FCIEC LKI AL F GYWQSKRN +DM+V  L + W+ +H  ++      ++SNNFGW  ++LRFF+IAG+HVTLKMLM TV+MSM+KSLF+I++MFLLM+VYALAG+ILFGSVKYG+NLGRHANFHNTFR+ ALL RIVTGEDWNKIMHDCM+QPPFC     FW++DCGNF+A+LIYFCSFY++ITY+MLNVLVAIIMENFSLFYSNDEDAI+SYNDIRNFQ AWN IDVNRKG +KA+YVRFLLRLIP++RVGFD  KKKDQQLFKEMCYEVE LRGG+DK+VSFHDVL +LAYR+VDI+KTLQLEEL+AREELEYAIEEEVARQTIA WIERCIFRNRQKHG LKF +  + E  I    DD     KK  L +++S +I +
Sbjct:    1 MFLSERKASHSRDTQGNIVGIDFSGDDGSDSTSKEWVYTRWAKIMLRTAAMISLASVSMNTPDTFKQVPVLMYITFILDLMVALLFTVEMISKMYIEGLFVPASS---------QSSGGIDQKRNRAYFQKSWNYFDAFMLFCIWASLALQCVEFYVTFRC--PLTSNDGENITYNSNISRDYYSCPNNENFRRNYGFLSIIRCPRPLILIRVFRAVLRLQLPQARVKAIFQRSTHQVYNVTVFLLFFMSLYGFLGVQFFGDELNYHCVLKTANETYITKQDLAIPDSYCNPAKNPDAQCPSNMKCIRIASSIQDDGGYAGFESFYISIFTVYQAASQEGWVFIMYRAMDCLASWKGVIYFMSMIFLVAWLVKNVFIAVLIETFAEIRVQFQQMWTPRHTADADSSKIFQFDGLTWKLVPVHESNPRGLAPKFFQETILRSTGFNVVIMVLVLANAITAAALHFNHQSLRDNDHMKVQLDGFYYAEILFTILFNFEAVFKIWCLGWGNYWHRSLFKFELFLCIGTTIHCIPILYRTEFTFLSVLRIVRLIKASPMLEDFCFKIFGPAKKLGSLILFTTCFLIITSTFSLQLFCCFQVFEPTFDR------------------------------------------FSTFPK------------AFMSMFQILTQKGWVAVMHDTMDVVENEAVTTGVAIYFVFYHLVVTLIVLSLFVAVILDNLELDEDIKKLKQLKLREISAETQQKLPMRLRVFEKFPNRPQMLQLTRLVSDFLMPKIRDSFMRQFAVISALEEVEDETIEEMLTTITKSQQTKEQSQLRINSLCINPSNANPHFNHYNALAKEALPSHTDVETLRAIKRKVHGLHGEEKFRAIIYLLNESNKTRLLTIEKTSNIGNRSLLSTQHQIRLDRRSTRNRVG-NPVGTNKSFRANGEVRGGNPSVTPAHNAESQTTTGNRTSHDDIKLLQQKAQLAELKRTQQEVELRENHPFFDRPLFVLGRENRFRRLCLVLVEARHKANDSMDSTDNGNF--IHKFLGLVTYLDWIAIFVTTLSCASMSLETPHFRLMNTPEVQICEYIFFVVMTLEMTLKIFANGLIFTPNALLKDFGGFLDLFIYIISLIFVSYMLRVDVIGPGSAGHLLMVLRCLRPLRIFCLVPQMRRVVYELVRGFREILMVSVLLVVFMFIFAVYGVHLFGGRLAICNDRSIMTKEKCVGRFMRELASTKLKSVKGESIKILVPRVWANPRNFNFDNIGNAILALFEVLSLEGWVEIRDVIKERIGPRHVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVDQRRWLDLKGRIRLTQPLQIPPRPKLHQEPGLTRNIVNP-KSNNLEKKSLKFRCFIYDITQHILFKRASATLVVANCFLLFFPFN---ELGTERSSWVKPRYQIQVSLGIIFTLFFCIECLLKIIALKFGGYWQSKRNRFDMLVAVLGVTWIILHFILRPIPEKHMISNNFGWFVLMLRFFTIAGRHVTLKMLMLTVVMSMYKSLFIIMSMFLLMMVYALAGVILFGSVKYGDNLGRHANFHNTFRATALLTRIVTGEDWNKIMHDCMIQPPFCRMHTTFWETDCGNFRAALIYFCSFYVIITYVMLNVLVAIIMENFSLFYSNDEDAIMSYNDIRNFQLAWNIIDVNRKGVVKAYYVRFLLRLIPRERVGFDLAKKKDQQLFKEMCYEVETLRGGRDKDVSFHDVLMVLAYRTVDITKTLQLEELIAREELEYAIEEEVARQTIAAWIERCIFRNRQKHGQLKFKMHSNIERQISTTLDDNDDFNKKSDLIMNKSVRIKN 1755

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BLAST of Voltage-dependent calcium channel vs. Ensembl Cavefish
Match: nalcn (sodium leak channel, non-selective [Source:ZFIN;Acc:ZDB-GENE-050410-12])

HSP 1 Score: 1338.55 bits (3463), Expect = 0.000e+0
Identity = 796/1748 (45.54%), Postives = 1087/1748 (62.19%), Query Frame = 2

Query:  164 ERKTSHTRETQPTLPGVEFATDDA-GDLTSVNWVYTTWARCAFKIXXXXXXXXXXXNTPETFKEYKWLFYVTYLLDIVVALLFTAEMFTKMKIKGIIRPSPYVIVRHLFFVKVSNNIENKRPHAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANS--IEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWLVKNVFIAILTETFAEIRVQFQQMWSPKNQTDADSS-KIFQTDGQR-WKLVPVYESKPHGLAPKLFQEIVLKSTAFNVIIMLLVLANAIVAAGLHF---NHDELTQTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHCM--WYRTQLTYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEPKFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPNDWAQQLFSTFSGIYFILINLIFSFAFMSMFQILTQKGWVIVMHDTMDMAKHRGLNALVAIYFVFYHLFVTLIVLSLFVAVILDNLELEEDIKKLKQLKLREMSAETQQKLPMRLRIFEKFPNRPQMIKPARLLSDFLIPKIRDSFMRQF----AQLPT-LEEENESDEMIAAAVSGVGVSSLPRALSIEIKRQIRGLKGN---DKLNAIIYLINESNKTRMIE-----QPIIYPTRSLLSTQHQIRTERRNLRNRMAATTMSINQKPRLNGEIRNMDFETNRKTEEANHFDIKILQQKAEQAEIKRNQQVDDLRENHPYFDKPLFTIGRESQFRQLCRMLVEAQY---KPDINSENPEKQTFYKLQKFFGLVTYLDWVMIFVTTTSCISMAFETPTKRVMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTK---LKLSGDS--PSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVGRINVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVDQRRWLDLKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTY-RENFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFIKAFYVRF-LLRLIPKDRVGFDFTKKKDQQLFKEMCYEVELLRGGKDKEVSFHDVLTMLAYRSVDISKTXXXXXXXXXXXXXXXXXXXXXRQTIATWIERCIFRNR---QKHGDLKFGLRESNE 5299
            +RK S   E QP     +F  D+   D   + W+   W     +  A++S+ SV  NTP+TF+ Y  L YVT+ LD ++  L+TAEM  KM I+GII                      K  ++Y++  W  FD  MV+ LW+S+ +Q FE+ +++   +P             +G+L   R PR LI+ R  R + +F LP++R+  IL RS  Q+++V++FLLFF+ LY ILGVQ FG   N HCV       ++    LAIPD+ C+P    G  CP   KCV + +      E GY+GF     S FTVY+AASQEGWVFIMYRA+D  P+W+   YFI++IFFLAWLVKNVFIA++ ETFAEIRVQFQQMW  ++ T + ++ ++F  D    W+LV V  +KPHG AP   Q++ ++S+ F++ I+ +V  + IVA+  ++   NH +    + FY AE+ FT+LF++EA+ KIWCLG+  Y   SLHKFE +L +GTT+H     Y +QLTYFQVLR+ RL+K SP LEDF +KIFG GKKLG L++FT+ LLI+ S++SLQ+FC ++    + DR                                          F+TF              AFMSMFQILTQ+GWV VM  T+    H     +VAIYF+ YHLF TLI+LSLFVAVILDNLEL+ED+KKLKQLK  E +A+T++KLP+RLRIFEKFPNRPQM+K ++L SDF +P+IR+SFM+QF     Q P+ L     S    +   S        + +  +++R I  ++     +K   +  ++    + RM+      QP     RS+LS QH IR ERR+LR+   +T+  I++   L    ++       +  +    +IK++Q+K EQAE+KR  Q ++LRENHPYFDKPLF +GRE +FR  CRM+V A++   K D  +   +   +++L    GLVTYLDWVMI VT  SCISM FE+P  RVM+   L++AEY+F + M+IE+ LK++A+G  FTP AV+RDFGGV+D FIY++ +IF+ ++     +   SG Q+LM+LRCLRPLRIF LVP MR+VV E+++GF+EI +VS+LL+  M  FA +GV +F GKLA CNDPT   ++DC G+F   +S++K   LKL  D   P F VPRVWANPRNFNFDN+GNAML LFEVLSL+GWVE+RDVI  RV   + IYIH+FVF+GC+IGLTLFVGVVIAN++ENKGTALLTVDQRRW DLK R+K+ QPLH+PPRP                 EN         R  +YD+TQH +FKR  A++VL   + L                              ++  +K+ A+S  GYWQS+RN YD++VT L +IW+ +H ++ + +   +     G   ++LRFF+I GKH +  M      +S+  S+   +A+ L +   +L+  +   S+       RHANF    ++I +LFRIVTGEDWNKIMHDCMVQPP CT  +  +W++DCGN+  +LIYFCSFY++I YIMLN+LVAII+ENFSLFYS +ED ++SYND+R+FQ  WN +D  R+G I    V+F L  L  +  V  D    KD+ LFK MCYE+E L  G D  V+FHDVL+ML+YRSVDI K+LQLEELLARE+LEY IEEEVA+QTI  W+++C+ R R   Q+   +   LRES +
Sbjct:    3 KRKQSSRVEAQPM---TDFGPDETLTDSADILWINKPWVHSLLRACAIISVISVCMNTPKTFEHYPPLEYVTFALDTLLMFLYTAEMIAKMHIRGII----------------------KGDNSYVKDRWCMFDGFMVVFLWVSLVLQVFEIAELVDQMSP-------------WGML---RIPRALIMIRAFRIYFRFELPRSRITNILKRSGEQIWSVSIFLLFFLLLYGILGVQMFGT-FNFHCVTNETERDNVTWNSLAIPDTHCSPD-GEGYQCPMGFKCVDLEDLGLSRQELGYSGFNELGTSIFTVYEAASQEGWVFIMYRAIDSFPRWRSYFYFITLIFFLAWLVKNVFIAVIIETFAEIRVQFQQMWGSRSSTTSTATTQMFHEDASGGWQLVAVDVNKPHGRAPACLQKL-MRSSVFHMFILSMVAVDVIVASSNYYKGKNHKK--DYDEFYLAEVAFTVLFDLEALLKIWCLGFTGYISSSLHKFESLLVVGTTLHIYPDLYHSQLTYFQVLRVVRLIKISPALEDFVYKIFGPGKKLGSLVVFTASLLIVMSAISLQMFCFVE----ELDR------------------------------------------FTTFPR------------AFMSMFQILTQEGWVDVMDQTLVAVGHM-WAPVVAIYFILYHLFATLILLSLFVAVILDNLELDEDLKKLKQLKQSEANADTKEKLPLRLRIFEKFPNRPQMVKISKLPSDFTVPRIRESFMKQFIDRQQQDPSCLFRRLPSASSSSCDHSKRSAIEDNKYIDQKLRRSIFSIRARNLLEKETTVNKILRACTRQRMLSGSFEGQPT--KERSILSVQHHIRQERRSLRH--GSTSQRISRGKSLETLTQDHTNTVRYRNAQREDSEIKMIQEKKEQAEMKRKVQEEELRENHPYFDKPLFIVGREHRFRNFCRMIVRARFNALKTDPITGAVKSTKYHQLYDLLGLVTYLDWVMIVVTICSCISMMFESPFTRVMHAPTLQIAEYVFVIFMSIELNLKIMADGLFFTPTAVIRDFGGVMDIFIYLVSLIFLCWL--PTDVPPESGAQLLMMLRCLRPLRIFKLVPQMRKVVREVLKGFKEIFLVSILLLTLMLVFASFGVQLFAGKLAKCNDPTIIHEEDCHGIFRINVSISKNLNLKLKPDEKKPGFWVPRVWANPRNFNFDNVGNAMLALFEVLSLKGWVEVRDVIIHRVDPTHGIYIHVFVFLGCMIGLTLFVGVVIANFNENKGTALLTVDQRRWEDLKSRLKIAQPLHLPPRP-----------------ENG------GFRAKMYDITQHPFFKRGIAVLVLAQSVLL-----------------------------SVKVTMKLIAMSPAGYWQSRRNRYDLLVTSLGVIWIILHFALLNAYTYMM-----GTCVIVLRFFTICGKHCSSHMCSLFHSLSLSLSVSRFLALSLSLSPLSLSLSLFSLSLLSLSLSHRHANFSTAGKAITVLFRIVTGEDWNKIMHDCMVQPPSCTPDKHRYWETDCGNYAGALIYFCSFYVIIAYIMLNLLVAIIVENFSLFYSTEEDQLLSYNDLRHFQIIWNMVDDKREGVIPTSRVKFLLRLLRGRLEVDLD----KDKLLFKHMCYEMERLHSGGD--VTFHDVLSMLSYRSVDIRKSLQLEELLAREQLEYTIEEEVAKQTIRMWLKKCLKRIRAKQQQSCSIILSLRESQQ 1576

[Close]

BLAST of Voltage-dependent calcium channel vs. Ensembl Cavefish
Match: cacna1ba (calcium channel, voltage-dependent, N type, alpha 1B subunit, a [Source:ZFIN;Acc:ZDB-GENE-060531-44])

HSP 1 Score: 180.259 bits (456), Expect = 1.042e-44
Identity = 176/650 (27.08%), Postives = 305/650 (46.92%), Query Frame = 2

Query: 3062 YLDWVMIFVTTTSCISMAFETPTKR--VMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGS-GKQI-----LMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTKLKLSGDSPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGW------VEIRDVIKARVGRINV-IYIHLFVFIGCLIGLTLFVGVVIANYSENKGTAL----LTVDQRRWLDLKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSL-FVIIAMFLLMLVYALAGIILFGSVKYGEN--LGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRENFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFIK 4945
            Y +  ++ V   S I++A E P +     N + LK  +Y+F    T EM +K++  G +  P +  RD   +LDF +    ++  A+        SG+ GK I     L +LR LRPL+    +P ++ V   +V   + +L + ++ ++FMF FAV  V +F GK   C D +K  +KDC G F   +   + ++S        PRVW     F++DN+  A LTLF V + EGW          D   +   RI + I+  ++  +     + +FV ++I  + E    AL    L  ++R  +D     K   PL                T     N+ SF     + R W + ++    F+    IM+ +N + L   ++   ++      +L   N+ +T +F +EC LKI A   + Y +   N++D V    S+  + V        N R+++ +F  +    R   +  +  T+++L+ T + S FK+L +V + + +L  +YA+ G+ +FG++   E+  +  H NF    +++ LLFR  TGE W++IM  C+     C  R      +CG+   +  YF SF  + +++MLN+ VA+IM+NF   Y   + +I+  + +  F + W   D    G IK
Sbjct: 1086 YFEMCILVVIAMSSIALAAEDPVQANAPRNNV-LKYLDYVFTGVFTFEMVIKMVDLGLLLHPGSYFRDLWNILDFIVVSGALVAFAF--------SGTKGKDISTIKSLRVLRVLRPLKTIKRLPKLKAVFDCVVNSLKNVLNILIVYILFMFIFAVIAVQLFKGKFFYCTDESKGLQKDCRGQF---LDYDRDEVSAQ------PRVWKK-YEFHYDNVLWAFLTLFTVSTGEGWPTTSVDATFEDQGPSPGYRIEMSIFYVVYFVVFPFFFVNIFVALIIITFQEQGDKALSECSLEKNERACIDFAINAK---PL----------------TRYMPQNQQSF-----QYRMWKFVVSPP--FEYSIMIMIALNTVVLMMKFHGAPDF---YEAMLKYLNIVFTALFSLECVLKIIAFGPLNYLKDAWNVFDFVTVLGSITDILV-----TEINDRLLNLSFLRLFRAARLIKLLRQGYTIRILLWTFVQS-FKALPYVCLLIAMLFFIYAIIGMQVFGNIDLNEDTAINHHNNFRTFLQALMLLFRSATGEAWHEIMLSCLSHRA-CDERSGTHGKECGS-DFAYFYFVSFIFLCSFLMLNLFVAVIMDNFE--YLTRDSSILGPHHLDEFIRVWAEYDPAACGRIK 1677

HSP 2 Score: 74.7146 bits (182), Expect = 1.214e-12
Identity = 60/241 (24.90%), Postives = 110/241 (45.64%), Query Frame = 2

Query: 1391 KLFQEIVLKSTAFNVIIMLLVLANAIVAAGLHFNHDELTQTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHCMWYRTQ---------LTYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEPKFD--RFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPNDWAQQLFSTFSGIYFILINLIFSFAFMSMF 2080
            + F   ++KS  F   ++ LV  N +  A +H+   E   T   Y AE VF  LF  E   K++ LG ++Y++ S + F+F + +G+    +W   +         L   ++LRIF++ K    L +    +  S K +  L+      +++ + + +QLF     +E +     F  FP A L +F ++T E W  VM   +     +           FS +YFI++ L  ++  +++F
Sbjct:  452 RFFIRRMVKSQGFYWTVLCLVGLNTLCVAIVHYEQPEWL-TYALYLAEFVFLGLFLTEMSLKMYGLGPRNYFHSSFNCFDFGVIIGSIFEVIWAAVKPGASFGISVLRALRLLRIFKVTKYWNSLRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNFEEETPTTNFDTFPAAILTVFQILTGEDWNAVMYHGIESQGGVKR-------GMFSSVYFIVLTLFGNYTLLNVF 684

HSP 3 Score: 63.5438 bits (153), Expect = 2.689e-9
Identity = 134/620 (21.61%), Postives = 232/620 (37.42%), Query Frame = 2

Query:  383 LDIVVALLFTAEMFTKMKIKGIIRPSPYVIVRHLFFVKVSNNIENKRPHAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILH---RSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSAN-ESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANSIEDEGGYAGFGTFHF-----SFFTVYQAASQEGWVFIMYRAMDCLPQWKGVS--YFISMIFFLAWLVKNVFIAILTETFAEIRVQFQQMWSPKNQTDADSSKIFQTDGQRWKLVPVYESKP-HGLAPKLFQEIVLK------STAFNVIIMLLVLANAIVAAGLHFNHDELTQTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHCMWYRTQ--------LTYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEP----KFDRFSNFPKAFLQIFTLVTEEGWIEVM----------TRAMIDAKKIPNDWAQQLFSTFSGI-YFILINLIFSFAFMSMFQILTQKGWVIVMH 2119
            LD V   +FT EM  KM   G++                        P +Y R  W   D I+V    ++                             K   +ST++S R L + R L++    RLP  ++KA+      S   V N+ +  + FM ++A++ VQ F      +C  +S   + D            C  +F   D    S +  ++    E          FH+     +F T++  ++ EGW      ++D   + +G S  Y I M  F            +    A I + FQ+      Q D   S+      +R  +     +KP     P+  Q    +      S  F   IM+++  N +V   + F+           Y  +VFT LF++E V KI   G  +Y   + + F+F+  LG+    +             L  F+  R+ +L++    +    +    S K L  + L  + L  I + + +Q+F +I + E       + F  F +A + +F   T E W E+M           R+    K+  +D+A   F +F  +  F+++NL F    M  F+ LT+   ++  H
Sbjct: 1121 LDYVFTGVFTFEMVIKMVDLGLLL----------------------HPGSYFRDLWNILDFIVVSGALVAFAFSG-----------------------TKGKDISTIKSLRVLRVLRPLKTIK--RLP--KLKAVFDCVVNSLKNVLNILIVYILFMFIFAVIAVQLFKGKF-FYCTDESKGLQKD------------CRGQFLDYDRDEVSAQ-PRVWKKYE----------FHYDNVLWAFLTLFTVSTGEGWPTT---SVDATFEDQGPSPGYRIEMSIFYVVYFVVFPFFFVNIFVALIIITFQE------QGDKALSECSLEKNERACIDFAINAKPLTRYMPQNQQSFQYRMWKFVVSPPFEYSIMIMIALNTVVLM-MKFHGAPDFYEAMLKYLNIVFTALFSLECVLKIIAFGPLNYLKDAWNVFDFVTVLGSITDILVTEINDRLLNLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGNIDLNEDTAINHHNNFRTFLQALMLLFRSATGEAWHEIMLSCLSHRACDERSGTHGKECGSDFAYFYFVSFIFLCSFLMLNL-FVAVIMDNFEYLTRDSSILGPH 1656

HSP 4 Score: 56.9954 bits (136), Expect = 2.788e-7
Identity = 56/212 (26.42%), Postives = 95/212 (44.81%), Query Frame = 2

Query: 4226 IFCIECALKITALSFIGYWQSKRNIYD---MVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTV----LLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRENFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFS 4840
            +F  E +LK+  L    Y+ S  N +D   ++ +   +IW  V               +FG   +    LLR F +     +L+ L+ ++L SM   + ++  +FL ++V+AL G+ LFG     E      NF     +I  +F+I+TGEDWN +M+  +             Q        S +YF    +   Y +LNV +AI ++N +
Sbjct:  504 LFLTEMSLKMYGLGPRNYFHSSFNCFDFGVIIGSIFEVIWAAVKPGA-----------SFGISVLRALRLLRIFKVTKYWNSLRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNFEEETPTTNFDTFPAAILTVFQILTGEDWNAVMYHGIES-----------QGGVKRGMFSSVYFIVLTLFGNYTLLNVFLAIAVDNLA 693

HSP 5 Score: 53.5286 bits (127), Expect = 3.009e-6
Identity = 55/251 (21.91%), Postives = 101/251 (40.24%), Query Frame = 2

Query:  530 AYLRHFWGCFDTIMVICLWISITIQTFEL--LKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWLVKNVFIAILTETFAEIRVQFQQ 1276
            +YLR+ W   D ++V+   ++     F+L  L+ ++   PL              L+S + S     L  VL+S +K  +P              +  + + L F + ++AI+G+ F+    +  C      E   +          C  +     +C    +C      I    G   F    F+  TV+Q  + EGWV I+Y A D         YFI +I   ++ + N+ + +L+  FA+ R + ++
Sbjct:  144 SYLRNGWNVMDFVVVLTGILTTVGADFDLRTLRAVRVLRPLK-------------LVSGIPS-----LQVVLKSIMKAMVP--------------LLQIGLLLFFAILMFAIIGLDFYMGKFHRTCFRIDTGEQAAEFP--------CGEE-APARTCENGTRCDSYW--IGPNFGITNFDNILFAILTVFQCITMEGWVEILYNANDASGNTWNWLYFIPLIIIGSFFMLNLVLGVLSGEFAKERERVEK 351

[Close]

BLAST of Voltage-dependent calcium channel vs. Ensembl Cavefish
Match: cacna1da (calcium channel, voltage-dependent, L type, alpha 1D subunit, a [Source:ZFIN;Acc:ZDB-GENE-030616-135])

HSP 1 Score: 177.178 bits (448), Expect = 8.820e-44
Identity = 173/673 (25.71%), Postives = 308/673 (45.77%), Query Frame = 2

Query: 3062 YLDWVMIFVTTTSCISMAFETPTKRV-MNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTKLKLSGD-SPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEIR----DVIKARVGRINVIYIHLFVFIGCLIG------LTLFVGVVIANYSENK----GTALLTVDQRRWLD--LKGRIKLTQPL--HIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRS--KILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKY--GENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRENFWQSD---CGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFIKAFYVRFLLRLIPKDRVGF 4999
            + + +++F+  +S  S+A E P +      I L   +Y F    T+E+ LK+   G      A  R++  +LD  +  + +  V++ I+   I   S  +IL +LR LRPLR       ++ VV  +    R I  + ++  +  F FA  GV +F GK   CND  K+  ++C G +        L   GD +   L  R W N  +FNFDN+  AM+ LF V + EGW  +     D  K   G I    + + +F    I       + +FVG VI  + E          L  +QR+ ++  LK R     PL  +IP  P                          + + W   +     F+ +  +++++N + L         YG  ++   ++   N+ +T +F +E  LK+ A    GY+    N++D +V   S++ + +   + +  +S  +S  F  +  ++R   +  +   ++ L+ T + S     +V + + +L  +YA+ G+ +FG V    G  + R+ NF    +++ LLFR  TGE W +IM  CM     C    ++   +   CG+   +++YF +FY++  ++++N+ VA+IM+NF   Y   + +I+  + +  F++ W+  D   KG IK   V  LLR I +  +GF
Sbjct:  763 FTNLILVFIMLSSA-SLAAEDPIRNFSARNIILGYFDYAFTAIFTVEIVLKMTTYGAFLHKGAFCRNYFNLLDLLV--VGVSLVSFGIQSSAI---SVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYRCNDEAKSSPEECKGTY-------ILYKDGDVNQPTLQKRHWHN-SDFNFDNVLMAMMALFTVSTFEGWPALLYKAIDSNKENFGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEKEYKNCELDKNQRQCVEYALKAR-----PLRRYIPKNP-------------------------YQYKFWY--VVNSTGFEYIMFVLIMLNTLCLAV-----QHYGQSQTFNYVMDILNMAFTAVFTVEMVLKLIAFKPRGYFGDAWNVFDALVVIGSIVDIVLS-EIDNTEDSARISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQIFGKVAMVDGTQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACMAG-KLCDPESDYNPGEEMTCGS-SFAIVYFITFYMLCAFLIINLFVAVIMDNFD--YLTRDWSILGPHHLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRI-QPPLGF 1378

HSP 2 Score: 108.227 bits (269), Expect = 7.368e-23
Identity = 151/655 (23.05%), Postives = 278/655 (42.44%), Query Frame = 2

Query: 3068 DWVMIFVTTTSCISMAFETP---TKRVMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKL-AIC-----NDPTKTEKKDC-VGVFDRKISVTKLKLSGDSPSFLVPRVWANPRN--FNFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVG-RINVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVD-------QRRWLDLKGRIK-LTQPLHI--------------PPRPKMRQDS--TQNRTDNNA-----------INENSFD------NRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLI-WVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGS-VKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRENFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDED 4864
            D  ++     +C+++A   P           +L+  EY F +  TIE  LK++A G +    A VR+   +LDF   +I I   A          G   + L   R LRPLR+   VP ++ V+  +++    +L +++L++  +  +A+ G+ +F GK+ A C        ++ E   C V    R  ++   +             W  P     NFDN   AMLT+F+ +++EGW ++   +   +G  +  +Y    V  G    L L +GV+   +S+ +  A    D       Q+   DLKG +  +TQ   I              P  P    +S  T+N    +            I+++ F       NR  + +C +    + + F  +  I+V +N + +     N     M  +++    N     +F  E  +K+ +L    Y+ S  N +D  V    +   + V + +       V          LLR F +     +L  L+ ++L SM     +++ +FL +++++L G+ +FG    + E   + + F N  +++  +F+I+TGEDWN +M+D ++           +     +     IYF   +I   YI+LNV +AI ++N     +++ED
Sbjct:   93 DIFILIAIFANCMALAVYIPFPEDDSNSTNHDLETVEYAFLIIFTIETFLKIIAYGLVMHQNAYVRNGWNMLDF---VIVIPLAAATHAHGGKPGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHATCFLVGSEMISEDEPAPCAVNGHGRTCTINGTECR---------EGWHGPNGGITNFDNFMFAMLTVFQCITMEGWTDVLYWMNDAMGMELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPDNEEEEEDSKRNPSVPASETESVNTENEKGEDEKATCCGPLCQKISKSKFSRRWRRWNRFCRRKCRL--AVKSVPFYWLVIILVFLNTLTISSEHYNQP---MWLTQVQDVANKVLLALFTCEMLVKMYSLGLQAYFVSLFNRFDCFVVCGGITETILVELEIMSPLGISVFR-----CVRLLRIFKVTRHWASLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQVFGGKFNFDETQTKRSTFDNFPQALLTVFQILTGEDWNVVMYDGIMA----------YGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNL----ADEED 711

HSP 3 Score: 70.8626 bits (172), Expect = 1.887e-11
Identity = 110/517 (21.28%), Postives = 212/517 (41.01%), Query Frame = 2

Query:  662 LITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILH---------RSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSY---------FISMIFFLAWLVKNVFIAILTETFAEI-RVQFQQMWSPKNQTDADSSKIFQTDGQRWKLVPVYESKPHGLAPKLFQEIVLKSTAFNVIIMLLVLANAIVAAGLHFNHDELTQTNGFYYA----ELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHCMW---------YRTQLTYFQVLRIFRLMK---ASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEP----KFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIP-NDW----AQQLFSTFSGIYFILINLIFSFAFMSMF 2080
            L++F  +   +S ++  R L + R LR+         R K + H         R+   +  VT  L F   ++A +GVQ F            ++  + K T +          +K GD    +++     NS  +      F     +   ++  ++ EGW  ++Y+A+D   +  G  Y         FI  I  +A+ + N+F+  +  TF E    +++     KNQ       +     +R+     Y+ K        F  +V  ST F  I+ +L++ N +  A  H+      Q+  F Y      + FT +F +E V K+     + Y+  + + F+ ++ +G+ V  +           R  +T+F++ R+ RL+K       +    +    S + L  + L  + L  I + + +Q+F  + + +     + + F  FP+A L +F   T E W E+M   M      P +D+         S+F+ +YFI   ++ +F  +++F
Sbjct:  842 LVSFGIQSSAISVVKILRVLRVLRPLRAI-------NRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQF---MFACIGVQLFKGKFYRCNDEAKSSPEECKGTYIL---------YKDGDVNQPTLQKRHWHNSDFN------FDNVLMAMMALFTVSTFEGWPALLYKAIDSNKENFGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEKEYKNCELDKNQRQCVEYALKARPLRRYIPKNPYQYK--------FWYVV-NSTGFEYIMFVLIMLNTLCLAVQHYG-----QSQTFNYVMDILNMAFTAVFTVEMVLKLIAFKPRGYFGDAWNVFDALVVIGSIVDIVLSEIDNTEDSARISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQIFGKVAMVDGTQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACMAGKLCDPESDYNPGEEMTCGSSFAIVYFITFYMLCAFLIINLF 1319

HSP 4 Score: 56.225 bits (134), Expect = 5.009e-7
Identity = 65/275 (23.64%), Postives = 116/275 (42.18%), Query Frame = 2

Query:  527 HAYLRHFWGCFDTIMVICLWISITIQ-------TFELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYS-MKCVKIANSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWLVKNVFIAILTETF------AEIRVQFQQMWSPKNQTDAD 1309
            +AY+R+ W   D ++VI L  +             + L+  +   PL              L+S + S     L  VL S +K  +P      +LH        + + +LF + +YAI+G++ F   ++  C L     S++   D   P +        G +C  +  +C +  +     GG   F  F F+  TV+Q  + EGW  ++Y   D +       YF+S++ F ++ V N+ + +L+  F      A+ R  FQ++   K Q + D
Sbjct:  154 NAYVRNGWNMLDFVIVIPLAAATHAHGGKPGGFDVKALRAFRVLRPLR-------------LVSGVPS-----LQVVLNSIIKAMVP------LLH--------IALLVLFVIIIYAIIGLELFIGKMHATCFLVG---SEMISEDEPAPCAVNG----HGRTCTINGTECREGWHG--PNGGITNFDNFMFAMLTVFQCITMEGWTDVLYWMNDAMGMELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLRE-KQQLEED 386

HSP 5 Score: 54.6842 bits (130), Expect = 1.363e-6
Identity = 59/238 (24.79%), Postives = 113/238 (47.48%), Query Frame = 2

Query: 1406 IVLKSTAFNVIIMLLVLANAIVAAGLHFNHDE-LTQTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFE-FILCLGTTVHCMWYRTQLTYF--------QVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFC---SIQIYEPKFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPNDWAQQLFSTFSGIYFILINLIFSFAFMSMF 2080
            + +KS  F  ++++LV  N +  +  H+N    LTQ      A  V   LF  E + K++ LG ++Y+    ++F+ F++C G T   +     ++          ++LRIF++ +    L +    +  S K +  L+L     +II S + +Q+F    +    + K   F NFP+A L +F ++T E W  VM   ++ A   P+     +      IYFI++ +  ++  +++F
Sbjct:  469 LAVKSVPFYWLVIILVFLNTLTISSEHYNQPMWLTQVQDV--ANKVLLALFTCEMLVKMYSLGLQAYFVSLFNRFDCFVVCGGITETILVELEIMSPLGISVFRCVRLLRIFKVTRHWASLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQVFGGKFNFDETQTKRSTFDNFPQALLTVFQILTGEDWNVVMYDGIM-AYGGPSSSGMIVC-----IYFIILFICGNYILLNVF 698

[Close]

BLAST of Voltage-dependent calcium channel vs. Ensembl Cavefish
Match: cacna1da (calcium channel, voltage-dependent, L type, alpha 1D subunit, a [Source:ZFIN;Acc:ZDB-GENE-030616-135])

HSP 1 Score: 175.252 bits (443), Expect = 3.106e-43
Identity = 173/673 (25.71%), Postives = 307/673 (45.62%), Query Frame = 2

Query: 3062 YLDWVMIFVTTTSCISMAFETPTKR-VMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTKLKLSGD-SPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEIR----DVIKARVGRINVIYIHLFVFIGCLIG------LTLFVGVVIANYSENK----GTALLTVDQRRWLD--LKGRIKLTQPL--HIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRS--KILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKY--GENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRENFWQSD---CGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFIKAFYVRFLLRLIPKDRVGF 4999
            + + +++F+  +S  S+A E P +      I L  A+Y+F    T E+ LK+   G      A  R++  +LD  +  + +  V++ I+   I   S  +IL +LR LRPLR       ++ VV  +    R I  + ++  +  F FA  GV +F GK   CND  K+  ++C G +        L   GD +   L  R W N  +FNFDN+  AM+ LF V + EGW  +     D  K   G I    + + +F    I       + +FVG VI  + E          L  +QR+ ++  LK R     PL  +IP  P                          + + W   +     F+ +  +++++N + L         YG  ++   ++   N+ +T +F +E  LK+ A     Y+    N +D ++   S++ + +   V +  +S  +S  F  +  ++R   +  +   ++ L+ T + S     +V + + +L  +YA+ G+ +FG V    G  + R+ NF    +++ LLFR  TGE W +IM  CM     C    ++   +   CG+   +++YF +FY++  ++++N+ VA+IM+NF   Y   + +I+  + +  F++ W+  D   KG IK   V  LLR I +  +GF
Sbjct:  777 FTNLILVFIMLSSA-SLAAEDPIRNFSARNIVLGYADYVFTSMFTFEIVLKMTTYGAFLHKGAFCRNYFNLLDLLV--VGVSLVSFGIQSSAI---SVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYRCNDEAKSSPEECKGTY-------ILYKDGDVNQPTLQKRHWHN-SDFNFDNVLMAMMALFTVSTFEGWPALLYKAIDSNKENFGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEKEYKNCELDKNQRQCVEYALKAR-----PLRRYIPKNP-------------------------YQYKFWY--VVNSTGFEYIMFVLIMLNTLCLAV-----QHYGQSQTFNYVMDILNMAFTAVFTVEMVLKLIAFKPRHYFTDAWNTFDALIVVGSVVDIAI-TEVNNTEDSARISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQIFGKVAMVDGTQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACMAG-KLCDPESDYNPGEEMTCGS-SFAIVYFITFYMLCAFLIINLFVAVIMDNFD--YLTRDWSILGPHHLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRI-QPPLGF 1392

HSP 2 Score: 104.76 bits (260), Expect = 9.606e-22
Identity = 165/739 (22.33%), Postives = 305/739 (41.27%), Query Frame = 2

Query: 2855 AEIKRNQQVDDLRENHPYFDKP---LFTIGRESQFRQLCRMLVEAQYKP-DINSENPEKQTFYKLQKFFGLVTYLDWVMIFVTTTSCISMAFETPTKRVMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIG---------------SGSGK------QILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKL-AIC-----NDPTKTEKKDC-VGVFDRKISVTKLKLSGDSPSFLVPRVWANPRN--FNFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVG-RINVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVD-------QRRWLDLKGRIK-LTQPLHIPP-----------RPKMRQDSTQNRTDNNAINENSFD-------------NRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLI-WVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGS-VKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRENFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDED 4864
            A+ KR Q     ++      +P   LF +   +  R+ C  LVE  +KP DI         F  +  F   +    ++      ++  +     P+ + +    ++  EY F +  TIE  LK++A G +    A VR+   +LDF I +I +  V   +     G               +  GK      + L   R LRPLR+   VP ++ V+  +++    +L +++L++  +  +A+ G+ +F GK+ A C        ++ E   C V    R  ++   +             W  P     NFDN   AMLT+F+ +++EGW ++   +   +G  +  +Y    V  G    L L +GV+   +S+ +  A    D       Q+   DLKG +  +TQ   I P            P +    T++    N   E+                NR  + +C +    + + F  +  I+V +N + +     N     M  +++    N     +F  E  +K+ +L    Y+ S  N +D  V    +   + V + +       V          LLR F +     +L  L+ ++L SM     +++ +FL +++++L G+ +FG    + E   + + F N  +++  +F+I+TGEDWN +M+D ++           +     +     IYF   +I   YI+LNV +AI ++N     +++ED
Sbjct:   35 AQKKRQQYAKSKKQGSSANTRPQRALFCLNLNNPIRRACISLVE--WKPFDI---------FILIAIFANCMALAVYIPFPEDDSNSTNHDLNCPSPQSI----IETVEYAFLIIFTIETFLKIIAYGLVMHQNAYVRNGWNMLDFVIVVIGLFSVVLEVLTKDGGQEDEGVEIPLAAATHAHGGKPGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHATCFLVGSEMISEDEPAPCAVNGHGRTCTINGTECR---------EGWHGPNGGITNFDNFMFAMLTVFQCITMEGWTDVLYWMNDAMGMELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPDNEEEEEDSKRNPSVPASETESVNTENEKGEDEKATCCGPLCRRWRRWNRFCRRKCRL--AVKSVPFYWLVIILVFLNTLTISSEHYNQP---MWLTQVQDVANKVLLALFTCEMLVKMYSLGLQAYFVSLFNRFDCFVVCGGITETILVELEIMSPLGISVFR-----CVRLLRIFKVTRHWASLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQVFGGKFNFDETQTKRSTFDNFPQALLTVFQILTGEDWNVVMYDGIMA----------YGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNL----ADEED 725

HSP 3 Score: 85.8853 bits (211), Expect = 4.721e-16
Identity = 130/593 (21.92%), Postives = 245/593 (41.32%), Query Frame = 2

Query:  527 HAYLRHFWGCFDTIMVICLWISITIQTFEL---LKVIKCETPLDSCKELITFWQKYG-----LLSTLRSPRPLILTR-------VLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYS-MKCVKIANSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWLVKNVFIAILTETF------AEIRVQFQQM---------------WSPKNQTDADSSKIFQTDGQRWKLVPVYESKPHGLAPKLFQE-------------------------IVLKSTAFNVIIMLLVLANAIVAAGLHFNHDE-LTQTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFE-FILCLGTTVHCMWYRTQLTYF--------QVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFC---SIQIYEPKFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPNDWAQQLFSTFSGIYFILINLIFSFAFMSMF 2080
            +AY+R+ W   D ++V+    S+ ++        +    E PL +         K G      L   R  RPL L         VL S +K  +P      +LH        + + +LF + +YAI+G++ F   ++  C L     S++   D   P +        G +C  +  +C +  +     GG   F  F F+  TV+Q  + EGW  ++Y   D +       YF+S++ F ++ V N+ + +L+  F      A+ R  FQ++               W  + +     ++  + D +R   VP  E++      +  ++                         + +KS  F  ++++LV  N +  +  H+N    LTQ      A  V   LF  E + K++ LG ++Y+    ++F+ F++C G T   +     ++          ++LRIF++ +    L +    +  S K +  L+L     +II S + +Q+F    +    + K   F NFP+A L +F ++T E W  VM   ++ A   P+     +      IYFI++ +  ++  +++F
Sbjct:  153 NAYVRNGWNMLDFVIVVIGLFSVVLEVLTKDGGQEDEGVEIPLAAATH--AHGGKPGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVP------LLH--------IALLVLFVIIIYAIIGLELFIGKMHATCFLVG---SEMISEDEPAPCAVNG----HGRTCTINGTECREGWHG--PNGGITNFDNFMFAMLTVFQCITMEGWTDVLYWMNDAMGMELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPDNEEEEEDSKRNPSVPASETESVNTENEKGEDEKATCCGPLCRRWRRWNRFCRRKCRLAVKSVPFYWLVIILVFLNTLTISSEHYNQPMWLTQVQDV--ANKVLLALFTCEMLVKMYSLGLQAYFVSLFNRFDCFVVCGGITETILVELEIMSPLGISVFRCVRLLRIFKVTRHWASLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQVFGGKFNFDETQTKRSTFDNFPQALLTVFQILTGEDWNVVMYDGIM-AYGGPSSSGMIVC-----IYFIILFICGNYILLNVF 712

HSP 4 Score: 70.4774 bits (171), Expect = 1.978e-11
Identity = 110/517 (21.28%), Postives = 211/517 (40.81%), Query Frame = 2

Query:  662 LITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILH---------RSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSY---------FISMIFFLAWLVKNVFIAILTETFAEI-RVQFQQMWSPKNQTDADSSKIFQTDGQRWKLVPVYESKPHGLAPKLFQEIVLKSTAFNVIIMLLVLANAIVAAGLHFNHDELTQTNGFYYA----ELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHCM---------WYRTQLTYFQVLRIFRLMK---ASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEP----KFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIP-NDW----AQQLFSTFSGIYFILINLIFSFAFMSMF 2080
            L++F  +   +S ++  R L + R LR+         R K + H         R+   +  VT  L F   ++A +GVQ F            ++  + K T +          +K GD    +++     NS  +      F     +   ++  ++ EGW  ++Y+A+D   +  G  Y         FI  I  +A+ + N+F+  +  TF E    +++     KNQ       +     +R+     Y+ K        F  +V  ST F  I+ +L++ N +  A  H+      Q+  F Y      + FT +F +E V K+     + Y+  + + F+ ++ +G+ V              R  +T+F++ R+ RL+K       +    +    S + L  + L  + L  I + + +Q+F  + + +     + + F  FP+A L +F   T E W E+M   M      P +D+         S+F+ +YFI   ++ +F  +++F
Sbjct:  856 LVSFGIQSSAISVVKILRVLRVLRPLRAI-------NRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQF---MFACIGVQLFKGKFYRCNDEAKSSPEECKGTYIL---------YKDGDVNQPTLQKRHWHNSDFN------FDNVLMAMMALFTVSTFEGWPALLYKAIDSNKENFGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEKEYKNCELDKNQRQCVEYALKARPLRRYIPKNPYQYK--------FWYVV-NSTGFEYIMFVLIMLNTLCLAVQHYG-----QSQTFNYVMDILNMAFTAVFTVEMVLKLIAFKPRHYFTDAWNTFDALIVVGSVVDIAITEVNNTEDSARISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQIFGKVAMVDGTQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACMAGKLCDPESDYNPGEEMTCGSSFAIVYFITFYMLCAFLIINLF 1333

[Close]

BLAST of Voltage-dependent calcium channel vs. Ensembl Cavefish
Match: cacna1sb (calcium channel, voltage-dependent, L type, alpha 1S subunit, b [Source:ZFIN;Acc:ZDB-GENE-051227-1])

HSP 1 Score: 172.555 bits (436), Expect = 1.979e-42
Identity = 163/646 (25.23%), Postives = 293/646 (45.36%), Query Frame = 2

Query: 3155 LKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTKLKLSGDSPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEI---------RDVIKARVGRINV-IYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVDQRRWLDLKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVF---VHISVQDN------------HNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKY--GENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRENFWQSD---CG-NFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFIKAFYVRFLLRLIPKDRVGF 4999
            L  A+ +F    TIE+ LK+   G I    +  R+   +LD  + ++ ++ +       ++      +IL +LR LRPLR       ++ VV  +    + I  + ++ ++  F FA  GV ++ GK   C DP K  +++C G F + +       +      +  R W N  +FNFDN+ NAML LF V + EGW E+          D       R++  ++  +++ I     + +FVG VI  + E         +    LD   R             +  Q + + R     I +N +  RV       + L    YF+ +  +++++N   L     N  ++    +K+  + NV +T +F  E  +K+ A    GY+    N++D ++   S++ V    V  +++ +             N+RV S  F  +  +LR   +  +   ++ L+ T + S      V + + +L  +YA+ G+ +FG +    G  + R+ANF    ++I +L+R VTGE W K+M  CM     C  R ++   +   CG NF  ++ YF SF ++  ++++N+ VA+IM+NF   Y   + +I+  + +  F++ W   D    G IK   V  LLR I +  +GF
Sbjct:  781 LAYADIVFTTVFTIEIVLKMTVYGAILHTGSFCRNAFNILDLIVVVVSLLSMGLESSAISV-----IKILRVLRVLRPLRALNRAKGLKHVVQCVFVAIQTIGNIILVTMLLNFMFACIGVQLYKGKFYSCTDPLKLTEEECQGTFVKHVR------NSLHDKEIGQRQWVN-SDFNFDNVPNAMLALFTVSTFEGWPELLYKAIDSDAEDRGPVFNNRMDTSLFFVIYLIIIAFFMMNIFVGFVIVTFREQGEQEFKNCE----LDKNQR-------------QCVQYALKARPLRCYIPKNPYQYRV-------WYLVTSCYFEYLMFLLIILNTCSLGLQHCNQSDH---ITKLADTLNVIFTVLFTFEMIVKLIAFKAKGYFGDPWNVFDFLIVIGSIVDVVLSQVDAALESSGGLYCLHGCTYEENARV-SITFFRLFRVLRLIKLLNRSEGIRNLLWTFIKSFQAFPHVALLIVMLFFIYAVIGMQVFGKIALVDGTEINRNANFQTFPQAILILYRTVTGEGWQKLMLACM-SGKLCDPRSDYAPGEEYTCGTNF--AVFYFLSFNMICGFLIINLFVAVIMDNFD--YLTRDWSILGPHHLDEFKKIWAEYDPEATGRIKHLDVVTLLRRI-QPPLGF 1380

HSP 2 Score: 80.1073 bits (196), Expect = 2.364e-14
Identity = 86/365 (23.56%), Postives = 160/365 (43.84%), Query Frame = 2

Query: 2864 KRNQQVDDLRE--NHPYFDKPLFTIGRESQFRQLCRMLVEAQYKPDINSENPEKQTFYKLQKFFGLVTYLDWVMIFVTTTSCISMAFETPTKR----VMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTI----------GSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTKLKLSGDSPSFLVPRV-----WANPRNF---NFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVGRINV-IYIHLFVFIGCLIGLTLFVGVVIANYSENK 3883
            K+ +++  L+    +P   + LF    ++ FR+ C  +VE  +KP                         + +++     +C+++A   P         NT  L+  EYIF V  T+E  LK++A G +F   A +R+   +LDF I  + +    + + VDTI          G G   + L   R LRPLR+   VP ++ V+  +++    +  V +L+   +  FA+ G+ ++  K+   +     E  D + + + ++  +    +G+     +        W  P NF   +FDN G AMLT+F+ +++E W  +   +   VG     IY    + +G    L L +GV+   +S+ +
Sbjct:   18 KQREKLKKLQATGGNPRPARSLFFFTLKNPFRKACTKIVE--WKP------------------------FEIIILLTIFANCVALAVFLPMPEEDTNYTNTT-LESLEYIFLVIFTLECFLKIIAYGLLFHEGAYLRNCWNILDFVIVFMGL----FTLAVDTINAIAGTPTEKGGGFDMKALRAFRVLRPLRLVSGVPSLQVVMNSILKAMIPLFQVVLLVFFLVTLFAIMGLELYKCKM---HKTCYYEGTDIIALRENEVP-SPCAQAGNGRRCTINGTECRGGWPGP-NFGITHFDNFGFAMLTVFQCITMESWTNVLYWVNDAVGNEWAWIYFVTMILLGSFFVLNLVLGVLSGEFSKER 346

HSP 3 Score: 72.0182 bits (175), Expect = 7.493e-12
Identity = 86/412 (20.87%), Postives = 167/412 (40.53%), Query Frame = 2

Query:  530 AYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANSIEDEGGYAG-------FGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWLVKNVFIAILTETFAEIRVQFQ-----QMWSPKNQTDAD---------SSKIFQTDGQRWKLVPVYESKP--------HGLAP---------------KLFQEIVLKSTAFNVIIMLLVLANAIVAAGLHFNHDELTQTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEF 1633
            AYLR+ W   D ++V     ++ + T   +      TP +              L   R  RPL L   + S       Q  + +IL ++   ++ V + + F ++L+AI+G++ +   ++  C  +  +   I + +  +P    +P  ++G+      +C    N  E  GG+ G       F  F F+  TV+Q  + E W  ++Y   D +       YF++MI   ++ V N+ + +L+  F++ R + +     Q    + Q D D          +++   D +   L+P+ +S           GL                 +L   + +KS  F  +++L+V  N +V A  H    E + T     A  +    F  E   K++  G ++Y+    ++F+F
Sbjct:  124 AYLRNCWNILDFVIVFMGLFTLAVDTINAI----AGTPTEKGGGF-----DMKALRAFRVLRPLRLVSGVPSL------QVVMNSIL-KAMIPLFQVVLLVFFLVTLFAIMGLELYKCKMHKTCYYEGTD--IIALRENEVP----SPCAQAGNG----RRCT--INGTECRGGWPGPNFGITHFDNFGFAMLTVFQCITMESWTNVLYWVNDAVGNEWAWIYFVTMILLGSFFVLNLVLGVLSGEFSKEREKCRSRGEYQKLRERQQMDEDLKGYMEWITHAEVLDADQEGQGLLPLKDSDSESEILFAIEGLNRIAYYYRLARRWNRVFRLKCAVWVKSRMFYWLVILVVFLNTLVIACEHHPQSE-SATRFQDVANDILLTCFAFEMFAKMYAFGLRAYFMSVFNRFDF 506

HSP 4 Score: 69.707 bits (169), Expect = 3.410e-11
Identity = 83/403 (20.60%), Postives = 169/403 (41.94%), Query Frame = 2

Query: 1079 SFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSY---------FISMIFFLAWLVKNVFIAILTETFAEIRVQFQQMWSPKN-QTDADSSKIFQTDGQRWKLVPVYESKPHGLAPKLFQEIVLKSTAFNVIIMLLVLANAIVAAGLHFNH-DELTQTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTV-----------------HCMW-------YRTQLTYFQVLRIFRLMK---ASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEP----KFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIP-NDWAQ----QLFSTFSGIYFILINLIFSFAFMSMFQILTQKGWVIVMHDTMDMAKHR 2146
            +   ++  ++ EGW  ++Y+A+D   + +G  +         F+  +  +A+ + N+F+  +  TF E   Q +Q +  KN + D +  +  Q   +   L       P+    +     ++ S  F  ++ LL++ N       H N  D +T+        ++FT+LF  E + K+     K Y+    + F+F++ +G+ V                 +C+         R  +T+F++ R+ RL+K    S  + +  +    S +    + L    L  I + + +Q+F  I + +     +   F  FP+A L ++  VT EGW ++M   M      P +D+A        + F+  YF+  N+I  F  +++F  +    +  +  D   +  H 
Sbjct:  952 AMLALFTVSTFEGWPELLYKAIDSDAEDRGPVFNNRMDTSLFFVIYLIIIAFFMMNIFVGFVIVTFRE---QGEQEF--KNCELDKNQRQCVQYALKARPLRCYIPKNPY----QYRVWYLVTSCYFEYLMFLLIILNTCSLGLQHCNQSDHITKLAD--TLNVIFTVLFTFEMIVKLIAFKAKGYFGDPWNVFDFLIVIGSIVDVVLSQVDAALESSGGLYCLHGCTYEENARVSITFFRLFRVLRLIKLLNRSEGIRNLLWTFIKSFQAFPHVALLIVMLFFIYAVIGMQVFGKIALVDGTEINRNANFQTFPQAILILYRTVTGEGWQKLMLACMSGKLCDPRSDYAPGEEYTCGTNFAVFYFLSFNMICGFLIINLFVAVIMDNFDYLTRDWSILGPHH 1343

[Close]

BLAST of Voltage-dependent calcium channel vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008004.1 (pep scaffold:Pmarinus_7.0:GL477228:88466:118438:1 gene:ENSPMAG00000007222.1 transcript:ENSPMAT00000008004.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 131.339 bits (329), Expect = 1.384e-30
Identity = 153/600 (25.50%), Postives = 264/600 (44.00%), Query Frame = 2

Query: 3173 IFFVAM-TIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRV-DTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTKLKLSGDSPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVG-------RINV---IYIHLFVFIGCLIGLTLFVGVVIANYS-----ENKGTALLTVDQRRWLDLKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRENFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSID 4921
            IF++A  ++EM LK++  G           F  +LD F+     + V+++ ++   + +    + L  LR LRPLR       MR VV  LV     I  V ++ ++F   F + GV +FGGK   C D  +  +     V +R +    L   G         +W N    N+DNI +A L L +V +LEGW+E         G         N+   ++  +FV IG    L LF+GVVI N++     E    ALLT DQ+++     R+  ++P    P+P+                     NRV++   + Y L     F+ +S  ++ +N + L        E     +KI+   N+ +T +F +E ALKI   + I Y++   +I+D  V  +SL  + +       + S  +   F  + ++     I      ++ L+ T+++S+   + + + + L+M +Y + G+ +F  + Y  ++    NF     S+ LLFR+ T   WN +M   +              +   N    + YF +F I    I++N+ VAII+ENF+     +E  +   +DI  F + W   D
Sbjct: 1060 IFYMAFFSMEMFLKMIGLGL----HKYFTSFWTLLDCFL-----VLVSWLNQLASAVPALKSLRSLRTLRALRPLRAISRWKGMRLVVNALVTSIPSISNVMLMCLLFWMVFGIAGVQLFGGKFFRCID-AEGNRLPATEVANRTV-CESLAAEG--------YLWVNAI-INYDNILSAYLALLQVATLEGWIEQMADASDSTGVDQQPSYNANIYSQMFFIIFVIIGSFFILNLFIGVVIDNFNSVHKREGALMALLTEDQQKFYKTMRRLYRSKPSKSIPQPQ---------------------NRVLR---FFYLLVHRRLFEYISTAVISLNMVMLASEHYKQSESFTNITKII---NLVFTGLFMLEAALKILG-NRIHYFRQPWDIFDFFVVCISLTEIVLETMASQVNFSPAILRVFRVVRLVRLLRLIRSVE-GIRKLIYTLVISLPALINIGLLLLLIMFMYGVLGVSIFRDLPYSGSITNMVNFETFANSMTLLFRLNTAGGWNDVMGSVL-------------GTKTQNAILVIAYFTTFVIFSNIIIINMYVAIILENFNEAQEQEETGVTD-DDIDMFYRVWGKFD 1596

HSP 2 Score: 57.7658 bits (138), Expect = 3.593e-8
Identity = 89/399 (22.31%), Postives = 151/399 (37.84%), Query Frame = 2

Query:  527 HAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANSIEDEG-----GYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCL-----PQWKGVSY----FISMIFFLAWLVKNVFIAILTETFAEIRVQFQQMWSPKNQTDADSSKIFQTDGQRWKLVPVYESKPHGLAPK------LFQEIVLKSTAFNVIIMLLVLANAIVAAGLHFNHDELTQTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYR---SLHKFEFILCLGTT 1654
            H Y   FW   D  +V+  W++        LK ++                    L TLR+ RPL   R +  +   RL    V   L  S   + NV +  L F  ++ I GVQ FG      C+    N   +  T++A                        +  S+  EG         +     ++  + Q A+ EGW+  M  A D       P +    Y    FI  +   ++ + N+FI ++ + F  +  +   + +   +   D  K ++T      +  +Y SKP    P+       F  +++    F  I   ++  N ++ A  H+   E + TN      LVFT LF +EA  KI  LG + +++R    +  F F++C+  T
Sbjct: 1080 HKYFTSFWTLLDCFLVLVSWLNQLASAVPALKSLRS-------------------LRTLRALRPL---RAISRWKGMRL----VVNALVTSIPSISNVMLMCLLFWMVFGIAGVQLFGGKF-FRCIDAEGNR--LPATEVANR---------------------TVCESLAAEGYLWVNAIINYDNILSAYLALLQVATLEGWIEQMADASDSTGVDQQPSYNANIYSQMFFIIFVIIGSFFILNLFIGVVIDNFNSVHKREGALMALLTE---DQQKFYKT------MRRLYRSKPSKSIPQPQNRVLRFFYLLVHRRLFEYISTAVISLNMVMLASEHYKQSE-SFTNITKIINLVFTGLFMLEAALKI--LGNRIHYFRQPWDIFDF-FVVCISLT 1415

HSP 3 Score: 53.9138 bits (128), Expect = 4.161e-7
Identity = 70/293 (23.89%), Postives = 128/293 (43.69%), Query Frame = 2

Query: 3959 HIPPRPKMRQDSTQNRTDNNAINENSFD--NRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLI-WVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSM--FKSLFVIIAMFLLMLVYALAGIILFGSVKYGENLGRHA-------NFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRENFWQSDCGNFQASLIYFCSFYIMITYIM 4801
            H+PP   +   + +   +      NS    +  +  R  +  L     F+    I+++ N + +       D Y    S  L   N   T IF  E  LK+TAL    Y+    NI+D  V   S++ W+   +S  + + S + +        +LR F +A K  TL +L++ +  ++   ++L VI A  L++ ++A+ G+ L G   Y  N  + +       NF + + S  ++FR++ GE W + +++C+V               C N     IY+C    ++TYI+
Sbjct:  522 HVPPCSLLSVRAARRPRERLVACLNSLRCCSAFVAFRQRLRTLVTSSVFETFITILIITNTVMMAI-----DYYNAPYSSALDIGNTVLTTIFIAEAVLKLTALFPRVYFHLGWNIFDFCVVITSVVEWILDSMSNTNINISIIRTFR------ILRVFKLAKKWKTLNLLIRVMKSAIGEMRNLTVIFA--LVIYIFAVIGMQLIGR-DYYHNRNKFSSGQVPRWNFLDFYSSFLMVFRVLCGE-WIEPLYECLV---------------CSN-----IYYCIPLFILTYIV 779

[Close]

BLAST of Voltage-dependent calcium channel vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002303.1 (pep scaffold:Pmarinus_7.0:GL476946:177796:226078:1 gene:ENSPMAG00000002078.1 transcript:ENSPMAT00000002303.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 102.064 bits (253), Expect = 1.211e-21
Identity = 129/542 (23.80%), Postives = 228/542 (42.07%), Query Frame = 2

Query: 3401 CLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTKLKLSGDSPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEIR-DVIKARVGRIN----------VIYIHLFVFIGCLIGLTLFVGVVIANYSENKGT-----ALLTVDQRRWLDLKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILASFNVTWTFIFCIECALKITALS---FIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNH-NSRVMSNNFGWMTVLLR---FFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMV--QP---PFCTYRENFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFI 4942
            C  P  + VV  LV     I+ V ++ ++F   F++ GV+ F GK + C + T           +  I   +      SPS      W N    NFDN+ +  L L +V + +GW++I    + +R                ++  +F+  G    L LF+GV+I N+++ K         LT +QR++ +   ++   +P    PRP            NN            K +   YDL     F+    IMVLI C+ +       DE        L   N+ +  IF  EC LK+ AL    F   W    N++D  V  LS+      +++ DN   S ++      +  L R      +      ++ L+  +LMS+     + + +F++M ++++ G+  FG +K+   +    NF     S+  LF+I T   W+ ++   ++  +P   P   +       +CGN      +F ++ I+   I++N+ +A+I+ENF++  +   +  +S +D   F   W   D N   FI
Sbjct: 1143 CARPLTQVVVNALVGAIPSIMNVLLVCLIFWLIFSIMGVNFFKGKFSKCVNSTDD------STMNESIIPNQNACLEQSPSLR----WKN-LPVNFDNVASGYLALLQVSTFKGWMDIMYAAVDSRQNNTEQPRFEESLGYYLFFVIFIIFGAFFILNLFIGVIIDNFNQQKKKFGGEDIFLTEEQRKYHNAMKKLGSKKPRKPVPRP------------NN------------KYQGMAYDLVHWQAFE--IGIMVLI-CLNMLTMMIEADEQSEAMKTALNITNIVFIGIFTTECVLKMFALRQYFFTFPW----NVFDFAVVTLSVF----DLAMADNSWLSNIVEPTLFRVVRLFRVGRILRLIRGAQGIRTLLFALLMSLPALFNIGLLLFVVMFIFSVFGMSNFGYLKHTAGIDEIFNFETFGGSMLCLFQITTSAGWDGLLAPTLLSKEPDCEPEAVHVGTNVVGNCGNKAIGCAFFVTYIIISFLIVVNMYIAVILENFNVATAESSEP-LSEDDFEMFYDIWGKFDPNATQFI 1637

HSP 2 Score: 71.633 bits (174), Expect = 1.887e-12
Identity = 70/285 (24.56%), Postives = 126/285 (44.21%), Query Frame = 2

Query: 3095 TSCISMAFETPTKRVMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLA-------------ICNDPTKTEKKDCVGVFDRKISVTKLKLSGDSP---SFLVPRVWANPRNF---NFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVGRINVIYIHLFVFIGCLIGLTLFVGVVIANYSE-NKGT 3889
            T+C+ MA  T         ELKV EY+F      E  +K+LA GF F     +RD    LD  + +I            +I   +    L + R +R L+   +VP ++ +V  L++  +++  V++L +  +  FA+  + +F G L                N     E KD    F + + +     S ++     F+  +   NP N+   N+DN G A L+LF +++ + W  +  +     G++ +I+  + +F+G    + L + VV  +Y E N+ T
Sbjct:  139 TNCVFMAINT---------ELKVVEYVFTAIYMFEALVKILARGFFFGAFTYLRDPWNWLDLAVLVIACF--------TSIPGFANLSALRMFRVMRALKTISVVPGLKTIVRALIQSVKKLSDVTILTLFCLSIFALIALQLFKGNLKNKCVRWPIPGNSNFINISQYLEDKDNY-YFHKNVPLLCSNSSENNTCPDGFICFKAGKNP-NYGYTNYDNFGWAFLSLFRLMTQDYWENLYQLTLRASGKVYMIFFVMVIFLGSFYLINLILAVVAKSYEEQNQAT 404

HSP 3 Score: 50.0618 bits (118), Expect = 6.212e-6
Identity = 106/527 (20.11%), Postives = 209/527 (39.66%), Query Frame = 2

Query:  761 LPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDC------LPQWK-GVSYFISMIFFLAWLVK---NVFIAILTETFAEIRVQF--QQMWSPKNQTDADSSKIFQTDGQRWKLVPVYESKPHGLAPKLFQEIVLKSTAFNVIIMLLVLANAIVAAGLHFNHDELTQT--NGFYYAELVFTILFNIEAVFKIWCL-------GWKSYWYR--SLHKFEFILC----LGTTVHCMWYRTQLTYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEPKFDR---FSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPNDWAQQLFSTFSGIYFILINLIFSFAFMSMFQILTQKGWVIVMHDTMDMAKHRGLNALVAIYFVFYHLFVTLIVLSLFVAVILDNLEL 2251
            L Q  V A++  +   + NV +  L F  +++I+GV FF    +  CV    N +D         DS  N         P    C++ + S+  +     F      +  + Q ++ +GW+ IMY A+D        P+++  + Y++  + F+ +      N+FI ++ + F + + +F  + ++  + Q    ++       +  K VP   +K  G+A  L     +   AF + IM+L+  N +    +    DE ++          +VF  +F  E V K++ L        W  + +   +L  F+  +     L   V    +R  +  F+V RI RL++ +  +    F +  S   L  + L    ++ I S   +  F  ++ +    D    F  F  + L +F + T  GW  ++   ++   K P+   +                                     +H   ++  + G  A+   +FV Y +   LIV+++++AVIL+N  +
Sbjct: 1147 LTQVVVNALVG-AIPSIMNVLLVCLIFWLIFSIMGVNFFKGKFSK-CV----NSTD---------DSTMNESI-----IPNQNACLEQSPSLRWKNLPVNFDNVASGYLALLQVSTFKGWMDIMYAAVDSRQNNTEQPRFEESLGYYLFFVIFIIFGAFFILNLFIGVIIDNFNQQKKKFGGEDIFLTEEQRKYHNAMKKLGSKKPRKPVPRPNNKYQGMAYDL-----VHWQAFEIGIMVLICLNMLT---MMIEADEQSEAMKTALNITNIVFIGIFTTECVLKMFALRQYFFTFPWNVFDFAVVTLSVFDLAMADNSWLSNIVEPTLFRV-VRLFRVGRILRLIRGAQGIRTLLFALLMSLPALFNIGLLLFVVMFIFSVFGMSNFGYLK-HTAGIDEIFNFETFGGSMLCLFQITTSAGWDGLLAPTLLS--KEPDCEPE------------------------------------AVHVGTNVVGNCGNKAIGCAFFVTYIIISFLIVVNMYIAVILENFNV 1605

[Close]

BLAST of Voltage-dependent calcium channel vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002291.1 (pep scaffold:Pmarinus_7.0:GL476946:177790:226078:1 gene:ENSPMAG00000002078.1 transcript:ENSPMAT00000002291.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 101.293 bits (251), Expect = 1.739e-21
Identity = 129/542 (23.80%), Postives = 228/542 (42.07%), Query Frame = 2

Query: 3401 CLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTKLKLSGDSPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEIR-DVIKARVGRIN----------VIYIHLFVFIGCLIGLTLFVGVVIANYSENKGT-----ALLTVDQRRWLDLKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILASFNVTWTFIFCIECALKITALS---FIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNH-NSRVMSNNFGWMTVLLR---FFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMV--QP---PFCTYRENFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFI 4942
            C  P  + VV  LV     I+ V ++ ++F   F++ GV+ F GK + C + T           +  I   +      SPS      W N    NFDN+ +  L L +V + +GW++I    + +R                ++  +F+  G    L LF+GV+I N+++ K         LT +QR++ +   ++   +P    PRP            NN            K +   YDL     F+    IMVLI C+ +       DE        L   N+ +  IF  EC LK+ AL    F   W    N++D  V  LS+      +++ DN   S ++      +  L R      +      ++ L+  +LMS+     + + +F++M ++++ G+  FG +K+   +    NF     S+  LF+I T   W+ ++   ++  +P   P   +       +CGN      +F ++ I+   I++N+ +A+I+ENF++  +   +  +S +D   F   W   D N   FI
Sbjct: 1060 CARPLTQVVVNALVGAIPSIMNVLLVCLIFWLIFSIMGVNFFKGKFSKCVNSTDD------STMNESIIPNQNACLEQSPSLR----WKN-LPVNFDNVASGYLALLQVSTFKGWMDIMYAAVDSRQNNTEQPRFEESLGYYLFFVIFIIFGAFFILNLFIGVIIDNFNQQKKKFGGEDIFLTEEQRKYHNAMKKLGSKKPRKPVPRP------------NN------------KYQGMAYDLVHWQAFE--IGIMVLI-CLNMLTMMIEADEQSEAMKTALNITNIVFIGIFTTECVLKMFALRQYFFTFPW----NVFDFAVVTLSVF----DLAMADNSWLSNIVEPTLFRVVRLFRVGRILRLIRGAQGIRTLLFALLMSLPALFNIGLLLFVVMFIFSVFGMSNFGYLKHTAGIDEIFNFETFGGSMLCLFQITTSAGWDGLLAPTLLSKEPDCEPEAVHVGTNVVGNCGNKAIGCAFFVTYIIISFLIVVNMYIAVILENFNVATAESSEP-LSEDDFEMFYDIWGKFDPNATQFI 1554

HSP 2 Score: 52.7582 bits (125), Expect = 1.206e-6
Identity = 40/148 (27.03%), Postives = 69/148 (46.62%), Query Frame = 2

Query: 3095 TSCISMAFETPTKRVMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKL 3538
            T+C+ MA  T         ELKV EY+F      E  +K+LA GF F     +RD    LD  + +I            +I   +    L + R +R L+   +VP ++ +V  L++  +++  V++L +  +  FA+  + +F G L
Sbjct:  141 TNCVFMAINT---------ELKVVEYVFTAIYMFEALVKILARGFFFGAFTYLRDPWNWLDLAVLVIACF--------TSIPGFANLSALRMFRVMRALKTISVVPGLKTIVRALIQSVKKLSDVTILTLFCLSIFALIALQLFKGNL 271

HSP 3 Score: 50.0618 bits (118), Expect = 6.659e-6
Identity = 104/527 (19.73%), Postives = 209/527 (39.66%), Query Frame = 2

Query:  761 LPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDC------LPQWK-GVSYFISMIFFLAWLVK---NVFIAILTETFAEIRVQF--QQMWSPKNQTDADSSKIFQTDGQRWKLVPVYESKPHGLAPKLFQEIVLKSTAFNVIIMLLVLANAIVAAGLHFNHDELTQT--NGFYYAELVFTILFNIEAVFKIWCL-------GWKSYWYR--SLHKFEFILC----LGTTVHCMWYRTQLTYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEPKFDR---FSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPNDWAQQLFSTFSGIYFILINLIFSFAFMSMFQILTQKGWVIVMHDTMDMAKHRGLNALVAIYFVFYHLFVTLIVLSLFVAVILDNLEL 2251
            L Q  V A++  +   + NV +  L F  +++I+GV FF    +  CV    N +D    + +I               P    C++ + S+  +     F      +  + Q ++ +GW+ IMY A+D        P+++  + Y++  + F+ +      N+FI ++ + F + + +F  + ++  + Q    ++       +  K VP   +K  G+A  L     +   AF + IM+L+  N +    +    DE ++          +VF  +F  E V K++ L        W  + +   +L  F+  +     L   V    +R  +  F+V RI RL++ +  +    F +  S   L  + L    ++ I S   +  F  ++ +    D    F  F  + L +F + T  GW  ++   ++   K P+   +                                     +H   ++  + G  A+   +FV Y +   LIV+++++AVIL+N  +
Sbjct: 1064 LTQVVVNALVG-AIPSIMNVLLVCLIFWLIFSIMGVNFFKGKFSK-CV----NSTDDSTMNESI--------------IPNQNACLEQSPSLRWKNLPVNFDNVASGYLALLQVSTFKGWMDIMYAAVDSRQNNTEQPRFEESLGYYLFFVIFIIFGAFFILNLFIGVIIDNFNQQKKKFGGEDIFLTEEQRKYHNAMKKLGSKKPRKPVPRPNNKYQGMAYDL-----VHWQAFEIGIMVLICLNMLT---MMIEADEQSEAMKTALNITNIVFIGIFTTECVLKMFALRQYFFTFPWNVFDFAVVTLSVFDLAMADNSWLSNIVEPTLFRV-VRLFRVGRILRLIRGAQGIRTLLFALLMSLPALFNIGLLLFVVMFIFSVFGMSNFGYLK-HTAGIDEIFNFETFGGSMLCLFQITTSAGWDGLLAPTLLS--KEPDCEPE------------------------------------AVHVGTNVVGNCGNKAIGCAFFVTYIIISFLIVVNMYIAVILENFNV 1522

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BLAST of Voltage-dependent calcium channel vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005302.1 (pep scaffold:Pmarinus_7.0:GL483978:134:5921:-1 gene:ENSPMAG00000004828.1 transcript:ENSPMAT00000005302.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 88.5817 bits (218), Expect = 6.191e-19
Identity = 65/229 (28.38%), Postives = 113/229 (49.34%), Query Frame = 2

Query: 4334 WVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKY--GENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCM----VQPPF-CTYRENFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFIKAFYVRFLLRLIPKDRVGF 4999
            W  +  S     ++  +S  F  +  +LR   +  +   ++ L+ T + S     +V + + +L  +YA+ G+ +FG +    G  + R+ NF    +++ LLFR  TGE W  IM  CM      P    +  E F    CG+   ++ YF SFY++  ++++N+ VA+IM+NF   Y   + +I+  + +  F++ W   D   KG IK   V  LLR I +  +GF
Sbjct:    1 WCLLQNSGSAAEDNNRISITFFRLFRVLRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMFGKIAMQDGSQINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGRRCDPDADASVGEEF---SCGS-SFAIFYFVSFYMLCAFLIINLFVAVIMDNFD--YLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHVDVVTLLRRI-QPPLGF 222

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BLAST of Voltage-dependent calcium channel vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010500.1 (pep scaffold:Pmarinus_7.0:GL477503:21958:35427:1 gene:ENSPMAG00000009511.1 transcript:ENSPMAT00000010500.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 87.4261 bits (215), Expect = 6.348e-19
Identity = 52/160 (32.50%), Postives = 86/160 (53.75%), Query Frame = 2

Query: 4499 FVIIAMFLLMLVYALAGIILFGSVKYGENLG--RHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRENFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFIKAFYVRFLLR 4972
            +V + + +L  +YA+ G+ +FG+VK  +  G   H NF   F+++ LLFR  TGE W +IM  C+ + P C       ++ CG+   +  YF SF  + +++MLN+ VA+IM+NF   Y   + +I+  + +  F + W   D    G I    +  LLR
Sbjct:    7 YVCLLIAMLFFIYAIVGMQVFGNVKLDDEGGITEHNNFQTFFQALMLLFRSATGEAWQEIMLSCLSKKP-CEQHSLNGENVCGS-DFAYFYFVSFIFLCSFLMLNLFVAVIMDNFE--YLTRDSSILGPHHLDEFVRIWGDYDPAATGRITYTKMYELLR 162

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BLAST of Voltage-dependent calcium channel vs. Ensembl Yeast
Match: CCH1 (Voltage-gated high-affinity calcium channel; involved in calcium influx in response to some environmental stresses as well as exposure to mating pheromones; interacts and partially co-localizes with Mid1p; however, evidence suggests CCH1 is not required for Mid1p function [Source:SGD;Acc:S000003449])

HSP 1 Score: 198.364 bits (503), Expect = 3.342e-51
Identity = 182/724 (25.14%), Postives = 337/724 (46.55%), Query Frame = 2

Query: 2867 RNQQVDDLRENHPYFDKPLFTIGRESQFRQLCRMLVEAQY--KPDINSENPEKQTFYKLQKFFGLVTYLDWVMIFVTTTSC--ISMAFETPTKRV---MNTIELKVA-EYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYI-ICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCL-VPHMRRVVFELV--RGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTKLKLSGDSPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVG----------RINVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVDQRRWLDLKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLT---QHIYFKRVSAIMVLINCIFLYF-PWNNDDEYGMKRSKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRENFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFY-SNDEDAIISYNDIRNFQQAWNSIDVNRKGFIKAFYV 4957
             ++++D L++ +P F+   +    + +FR+ C+ LV      + D +    +    Y  + +F  +    +V IF   T    +   + TP  R+   M T     A +  F  A +IE  +K +A+GFI++P A +R+    +DF + I + I  +AY+       +G+  +I   L  LR LR  CL + +  R  F LV   G  +I    ++ +  +F F V+G+ IF G+L  CND +   + DC   +   +    +         + PRV+  P   + D+  +A  +L++++SLEGWV++ + +    G            N +++ LF F+  +  L LFV  ++ N +   G+A  T++++ WL+ +  +   +P  IP                N I        + +VR + Y L    ++ Y+     +++ ++ I L    +N  +  G +    + S     T +F I+ AL +       Y++ K N   + +  ++ I   V   V  +H      +N     +L+ F  I  ++ TL  L++T + S+   L +     +L LVYA+A   +FG  + G N   + NF    +S+ +LFR   GE WN IM D  V  P+C+  +N   +DCG+   + +   S+ I+  YI +N+ V++I+ NFS  Y S    + I+ ++I+ + +AW+  D +  G ++  Y+
Sbjct: 1139 EDEKLDYLKK-YPLFNYSYYFFSPQHRFRRFCQRLVPPSTGKRTDGSRFFEDSTDLYNKRSYFHHIERDVFVFIFALATILLIVCSCYVTPLYRMHHKMGTWNWSSALDCAFIGAFSIEFIVKTVADGFIYSPNAYLRNPWNFIDFCVLISMWINLIAYLK-----NNGNLSRIFKGLTALRALR--CLTISNTARQTFNLVMFDGLNKIFEAGLISLSLLFPFTVWGLSIFKGRLGTCNDGS-LGRADCYNEYSNSVFQWDI---------MSPRVYQQPY-LHLDSFASAFSSLYQIISLEGWVDLLENMMNSSGIGTPATVMGSAGNALFLVLFNFLSMVFILNLFVSFIVNNQARTTGSAYFTIEEKAWLESQKLLSQAKPKAIP----------------NLI-------ELSRVRQFFYQLAVEKKNFYYASFLQVVLYLHIIMLLSRSYNPGNLIGYQGVYFMFS-----TSVFLIQEALHMCGEGPRLYFRQKWNSIRLSIIIIAFIMNAVAFHVPASH---YWFHNIKGFFLLVIFLFIIPQNDTLTELLETAMASLPPILSLTYTWGVLFLVYAIALNQIFGLTRLGSNTTDNINFRTVIKSMIVLFRCSFGEGWNYIMADLTVSEPYCSSDDNSTYTDCGSETYAYLLLMSWNIISMYIFVNMFVSLIIGNFSYVYRSGGSRSGINRSEIKKYIEAWSKFDTDGTGELELSYL 1812

HSP 2 Score: 57.7658 bits (138), Expect = 2.123e-8
Identity = 65/278 (23.38%), Postives = 104/278 (37.41%), Query Frame = 2

Query:  512 ENKRP----HAYLRHFWGCFDTIMVICLWIS--ITIQTFELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCV-LQSANESDIKITDLAIPDSFCNPKFK----------------SGDSCPYSMKCVKIANSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWLVKNVFIAILTETFAEIRVQFQQ 1276
            EN+RP     A+ R  W   D +  +  W+   ++I++++    I+   PL   + L       G+ S LR              LK+ +PQ             + NV+  L++F   + ILGVQ F       CV     + +D    D+     + +P  K                 G  CP   KCV  AN      G   F     S   V+   S   +  +MY  MD   +     +FI  IF L   + N+ IA+L  +F     ++++
Sbjct:  478 ENQRPFGTPRAFARSSWNRIDLVSSVSFWLGMFLSIKSYDTKTGIRIFKPLAILRILRLVNVDTGMPSILRG-------------LKYGIPQ-------------LVNVSSMLVYFWIFFGILGVQIFQGSFRRQCVWFNPEDPTDTYQYDMQFCGGYLDPVTKRKQNYIYEDGSEGSVSKGFLCPQYSKCVSNANPY---NGRISFDNIVNSMELVFVIMSANTFTDLMYYTMDS-DEMAACLFFIVCIFVLTIWLLNLLIAVLVSSFEIANEEYKK 725

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BLAST of Voltage-dependent calcium channel vs. Ensembl Nematostella
Match: EDO45175 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RTZ8])

HSP 1 Score: 1084.71 bits (2804), Expect = 0.000e+0
Identity = 661/1682 (39.30%), Postives = 976/1682 (58.03%), Query Frame = 2

Query:  257 WVYTTWARCAFKIXXXXXXXXXXXNTPETFKEYKWLFYVTYLLDIVVALLFTAEMFTKMKIKGIIRPSPYVIVRHLFFVKVSNNIENKRPHAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWLVKNVFIAILTETFAEIRVQFQQMWSPKNQT-DADSSKIFQTDGQRWKLVPVYESKPHGLAPKLFQEIVLKSTAFNVIIMLLVLANAIVAAGLHFNHDELTQTNGFYY--AELVFTILFNIEAVFKIWCLGWKSYWYRS-LHKFEFILCLGTTVHCMWYRTQ---LTYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEPKFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPNDWAQQLFSTFSGIYFILINLIFSFAFMSMFQILTQKGWVIVMHDTMDMAKHRGLNALVAIYFVFYHLFVTLIVLSLFVAVILDNLELEEDIKKLKQLKLREMSAETQQKLPMRLRIFEKFPNRPQMIKPARL--LSDFLIPKIRDSFMRQFAQLPTLEEENESDEMIAAAVSGVG-------VSSLPRALSIEIK----------RQIRGLKGNDKLNAIIYLINESNKTRMIEQPIIYPTR----------SLLSTQHQIRTERRNLRNRMAATTMSINQKPRL-NGEIRNMDFETNRKTEEANH-FDIKILQQKAEQAEIKRNQQVDDLRENHPYFDKPLFTIGRESQFRQLCRMLVEAQYK-PDINSENPEKQTFYKLQ---KFFGLVTYLDWVMIFVTTTSCISMAFETPTKRVMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTK--LKLSGDSPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVGRINVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVDQRRWLDLKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYF-PWNNDDEYGMKRSKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRENFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFIKAFYVRFLLRL--------IPKDRVGFDFTKKKDQQLFKEMCYEVELLRGGKDKEVSFHDVLTMLAYRSVDISKT 5143
            W+ + W +   ++ ++LSL S++ NTPETF+    LFYVT LLDI +A +FT EM  +++  G             F V++          AYL+     F+  M+I + +SI +Q  EL        P             Y + S  R+PR LI+ RV + F+ FRL       +  R   Q+++VT+F L+FM+L +I+GVQ FG   N++CV  + + S++  +DL +PD+ C+   + G  CP    C +I N          F  F +S  TVY +++QEGWV +MY+ M+   +   V YF+ M+FF+AWLVKNVFIA+++ETFA++R Q+ +  S   +     SS + +  G  W LV V      G AP   + IV    A    I   VL +A++ A            NG +   A+ VFTILF+IEA+ KIWC+G+++Y   S +  FEFIL +G+TV  +        L  F V+R+ RL+ A P L+DFC KIFG+GK LG +ILFT   ++++S++S+QLF +++                                            D +  +F T+              +  SMFQI TQ+GWV ++  +M  A+  G  ALVAI+ + YHLF +LI++S+FVAVI+DNL+++ED+K +KQ K+ E ++ T +KLP+RLR++E+F   P+++K +R+   SDF  PKIR+SFM++F     +  EN  D  I  ++S  G       V S   ALS+ +K          R  R  +    ++A   LIN+SN  R + Q  I P+            L     +IRT R     R A T   + +   + N   +N+  + ++        +DI+ +++K EQA  KR  Q + LRENHP+FD+PLF + R+S  R   + +V A+Y  P  + E   +     ++   K     TYL+W M+F+T  SC++M  ETP  R  + I     E+IF V M++E+ +++LA+G +FTPKAV+++FGG LD  IY+I +I++ +  +  ++   SG Q+LMI RCLRPLR+  L+P M++V+ ELV G++EIL VS L ++ MF+FA+YGV +F GKL  C+DP+ T K DC G+F  +++  +    LSG+ PS LVPRVW NPRNF+FD++  A L LFE LSLEGW+EIRDVI   VG     Y+H +V +G +IGLTLFVGVV+ N++++KG ALLTVDQRRW DLK R++L QPLH+PPRP           D+N I +             +YDL Q + ++RV A++VL+ C  L    W   D       +++ S     T +F I+  LK+ A +  GYW S+RN +D+ +T L LIWV ++ S++ N  +  ++  FG + ++ RF +++GKH TLKMLM TV+MS+ KS F I  + +LM+ Y+L G+ILFG+VKYGE + R+ANF  +F ++ LLFR+ TGEDWNKIMHDCMV  P+CT  ENFW SDCGN+ ASLI+F SFYI++++I+LNV VA+I+ENFSLFY++DED+++S  D+R+FQ AWN +D  RKG +     +  +R+          K R+  D         F+ MC E+E LR G D  VSFHDVL ++AYRSVDIS++
Sbjct:    7 WLKSWWFKRLIQVCSVLSLISMAMNTPETFQNIPSLFYVTLLLDIALATVFTVEMIAQIRKFG-------------FIVEL---------RAYLKRPQCIFNLSMLILIVLSIILQLVELTGY----KP-----------DPYIIFSIPRAPRALIMVRVFKLFVNFRLDN----EVSRRCRRQIWSVTIFFLYFMTLASIIGVQMFGSK-NYYCVRNTTDLSNVTYSDLLLPDARCSISHERGYFCPNDFYCAQI-NLKPFMADRRYFDHFFYSLLTVYTSSTQEGWVLVMYQMMNVRSEVLVVIYFVLMMFFIAWLVKNVFIAVVSETFADVRSQYSKSRSSSRRRYTGLSSLVIKDQGAGWHLVSVDHEASKGHAPLPIRNIVASRYA-RWFIWTAVLVDALIQAN-----------NGSWRRRAQFVFTILFDIEALIKIWCVGFRTYLNSSRMQFFEFILAVGSTVFALPVLMSIDALAIFHVMRVLRLIGAVPGLQDFCLKIFGTGKNLGSVILFTLFFVMVSSAISMQLFLTLK--------------------------------------------DGSDTIFGTYLQ------------SLSSMFQIFTQEGWVEIVEKSMISAEAYG-AALVAIFLIAYHLFSSLIIMSVFVAVIVDNLDIDEDLKIMKQRKMGEETSVTHEKLPLRLRVYERFKEDPRIVKMSRMKFASDFPTPKIRESFMKRF-----VNTENVDDMPIDLSMSVPGDSTVSSNVGSRRTALSLPVKLLNSSMPEMNRSTRLFRKQSTISA---LINDSNHRRTLAQ--IAPSEINPRGGAKSAGLRMASRRIRTARTG---RGAVTEADVKRAMEMANRGGKNLQSQISQDEAPVRRDWDIQSVREKREQAASKRRMQEETLRENHPFFDQPLFMLPRDSWLRSFLKSVVHARYTIPPGHIERATRGRLINIETIHKIIATQTYLEWTMVFLTLASCLAMMTETPQVRTFDNIATSAFEHIFVVGMSLELGIRILADGLVFTPKAVIQNFGGALDTMIYLISLIYICWQPK--SVPVNSGAQMLMIFRCLRPLRVLTLMPKMKKVILELVGGYKEILKVSALQLILMFSFAIYGVQVFSGKLGRCSDPSITVKSDCKGLFYVQLADPREVTTLSGEPPSMLVPRVWKNPRNFSFDDVLQAFLALFEALSLEGWLEIRDVIDYAVGSEYGFYVHTYVLLGSMIGLTLFVGVVVTNFNQHKGIALLTVDQRRWQDLKKRLRLAQPLHLPPRP-----------DDNGIRKT------------LYDLVQSVIYRRVVAVVVLVECGTLAVGQWTTVDA---PVREVITSTAAVCTLLFVIDTILKVIAYTGPGYWHSQRNRFDVFLTSLGLIWVVLNFSLKGNEKAYTVATIFGVVIIIFRFLTLSGKHDTLKMLMLTVVMSLVKSFFTIAVLVILMMCYSLMGVILFGTVKYGEAVNRYANFGTSFNAMILLFRVTTGEDWNKIMHDCMVGEPYCTPAENFWLSDCGNYAASLIFFMSFYIVVSFILLNVFVAVIIENFSLFYASDEDSLLSNTDLRDFQMAWNLVDKGRKGVMSVPQAKLFMRVYIFFKQNNFLKGRLDMD----NRTVPFRHMCCEIEKLRNGGD--VSFHDVLGIIAYRSVDISRS 1529

[Close]

BLAST of Voltage-dependent calcium channel vs. Ensembl Nematostella
Match: EDO45174 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RTZ7])

HSP 1 Score: 1068.14 bits (2761), Expect = 0.000e+0
Identity = 653/1684 (38.78%), Postives = 975/1684 (57.90%), Query Frame = 2

Query:  257 WVYTTWARCAFKIXXXXXXXXXXXNTPETFKEYKWLFYVTYLLDIVVALLFTAEMFTKMKIKGIIRPSPYVIVRHLFFVKVSNNIENKRPHAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWLVKNVFIAILTETFAEIRVQFQQMWSPKNQT-DADSSKIFQTDGQRWKLVPVYESKPHGLAPKLFQEIVLKSTAFNVIIMLLVLANAIVAAGLHFNHDELTQTNGFY--YAELVFTILFNIEAVFKIWCLGWKSYWYRS-LHKFEFILCLGTTVHCMWYRTQ---LTYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEPKFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPNDWAQQLFSTFSGIYFILINLIFSFAFMSMFQILTQKGWVIVMHDTMDMAKHRGLNALVAIYFVFYHLFVTLIVLSLFVAVILDNLELEEDIKKLKQLKLREMSAETQQKLPMRLRIFEKFPNRPQMIKPARL--LSDFLIPKIRDSFMRQFAQLPTLEE-------ENESDEMIA--------AAVS---GVGVSSLPRALSIEIKRQIRGLKGNDKLNAIIYLINESNKTRMIEQPIIYPTR----------SLLSTQHQIRTERRNLRNRMAATTMSINQKPRLNGEIRNMDFETNRKTEEA---NHFDIKILQQKAEQAEIKRNQQVDDLRENHPYFDKPLFTIGRESQFRQLCRMLVEAQYK-PDINSENPEKQ---TFYKLQKFFGLVTYLDWVMIFVTTTSCISMAFETPTKRVMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTK--LKLSGDSPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVGRINVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVDQRRWLDLKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYF-PWNNDDEYGMKRSKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRENFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFIKAFYVRFLLRL--------IPKDRVGFDFTKKKDQQLFKEMCYEVELLRGGKDKEVSFHDVLTMLAYRSVDISKT 5143
            W+ + W +   ++ ++LSL S++ NTPETF+    LFYVT +LDI +A +FT EM  +++  G I     V +R                 AYL+     F+  M+I + +SI +Q  EL        P             Y + S  R+PR LI+ RV + F+ FRL       +  R   Q+++VT+F L+FM+L +I+GVQ FG   N++CV  + + S++  +DL +P++ C+   + G  CP +  C +I N  +       F  F +S  TVY +++QEGWV +MY+ M+   +   V YF+ M+FF+AWLVKNVFIA+++ETFA++R Q+ +  S   +     SS + +  G  W LV V      G AP   + IV    A    I   VL +A++ A            NG +   A+ VFTILF+IEA+ KIWC+G+++Y   S +  FEFIL +G+TV  +        L  F V+R+ RL+ A P L+DFC KIFG+GKKLG +ILFT   ++++S++S                        +Q+F  +++   I++                        G Y   ++        SMFQI TQ GWV+++   M  A+  G  A+VAI+ + YHLF +LI++S+FVAVI+DNLE++E++K +KQ K+ E ++ T +KLP+RLR++E+F   P+++K +RL   SDF  PKIR+SFM++F    ++++           DE ++        AA+S    +  SS+P     EI R  R  +    ++A   LIN++N  R + Q  + PT            L     +IRT R     R A T   + +   +          +    +EA     +DI+ +++K EQA  KR  Q + LRENHP+FD+PLF + R+S  R L + +V A+Y  P    E   +    T   + K     TYL+W M+F+T  SC++M  ETP  R  + I     E+IF V M++E+ +++LA+G +FTPKAV+++FGG LD  IY+I +I++ +  +  ++   SG Q+LMI RCLRPLR+  L+P M++V+ ELV G++EIL VS L ++ MF+FA+YGV +F  +L  C+DP+   K +C G+F   ++  +    L+G  P+ LVPRVW NPRNF+FD++  A L LFE LSLEGW+EIRD I   VG     Y+H +V +G +IGLTLFVGVV+ N++E+KG ALLTVDQRRW DLK R++L QPLH+PPRP           D+N I +             +YDL Q + ++RV A++VL+ C  L    W   D       +++ S     T +F ++  LK+ A +  GYW S+RN +D+++T L LIWV ++ S++ N N+ ++S  FG + ++ RF +++GKH  LKMLM TV+MS+ KS F I  + +LM+ Y+L G+ILFG+VKYGE + R+ANF  +F ++ LLFR+ TGEDWNKIMHDCMV  P+CT  ENFW+SDCGN+ ASLIYF +FYI++++I+LNV VA+I+ENFSLFY++DED+++S  D+R+FQ AWN +D  RKG +     +  +R+          K R+  D         F+ MC E+E LR G D  VSFHDVL ++AYRSVDIS++
Sbjct:    3 WLKSWWFKRLIQVCSVLSLMSMAMNTPETFRNVPSLFYVTLVLDITLATVFTVEMIAQIRKFGFI-----VDLR-----------------AYLKRPQCIFNLSMLILIVLSIILQLVEL----TGYKP-----------DPYIIFSIPRAPRALIMFRVFKLFVNFRLDN----EVSRRCRRQIWSVTIFFLYFMTLASIIGVQMFGSK-NNYCVRNTTDLSNVTYSDLLLPEARCSISNEKGYICPANFYCAQI-NLDKFMAARRYFDHFFYSLLTVYTSSTQEGWVLVMYQMMNVRSEVLVVIYFVLMMFFIAWLVKNVFIAVVSETFADVRSQYSKSRSSSRRRYTGLSSLVIKDQGAGWHLVSVDHEASKGHAPLPIRNIVASRYA-CWFIWFAVLVDALIQAN-----------NGSWRRQAQFVFTILFDIEALIKIWCVGFRTYLNSSRMQFFEFILAVGSTVFALPVLMSIDALAIFHVMRVIRLIAAIPGLQDFCLKIFGTGKKLGSVILFTLFFVMVSSAIS------------------------MQLFLTLSDRSGIKIF-----------------------GTYLTSLS--------SMFQIFTQDGWVVIVEKAMTSAEVYG-AAVVAIFLIAYHLFSSLIIMSVFVAVIVDNLEIDEEVKIMKQRKMGEETSVTHEKLPLRLRVYERFKEDPRLVKMSRLKFASDFPTPKIRESFMKRFVNTESVDDMPLDLSMSVPGDESLSPNRMRGRRAAISLPVKLLNSSVP-----EINRSTRIFRKQSTVSA---LINDANHRRTLAQ--LSPTELTPRGGVKSAGLRMASRRIRTARTG---RGAVTEADVKRAMEMASH-GGKKIHSQLSQDEAPTRRDWDIQSVREKREQAASKRRMQEETLRENHPFFDQPLFMLPRDSWLRSLLQSVVHARYIIPPGYIERATRNRLITMDTIHKIIATQTYLEWTMVFLTLASCLAMMTETPQVRTFDNIATSAFEHIFVVGMSLELGVRILADGLVFTPKAVIQNFGGALDIMIYLISLIYICWQPK--SVPVNSGAQMLMIFRCLRPLRVLTLMPKMKKVILELVGGYKEILKVSALQLILMFSFAIYGVQVFSRRLGRCSDPSIKLKSECKGLFYMPLANPREIFTLNGKPPAMLVPRVWKNPRNFSFDDVFQAFLALFEALSLEGWLEIRDTIDYAVGPEYGFYVHTYVLLGSMIGLTLFVGVVVTNFNEHKGIALLTVDQRRWQDLKKRLRLAQPLHLPPRP-----------DDNGIRKT------------LYDLVQSVIYRRVVAVVVLVECGTLAVGQWTTVDT---PVREVITSTAAVCTLLFVVDTILKLIAYTVRGYWHSRRNRFDLLLTSLGLIWVVLNFSLKGNENAYLISTIFGVVIIIFRFLTLSGKHDMLKMLMLTVVMSLVKSFFTIAVLVILMMCYSLMGVILFGTVKYGEAINRYANFGTSFNAMILLFRVTTGEDWNKIMHDCMVGEPYCTPEENFWESDCGNYTASLIYFITFYIVVSFILLNVFVAVIIENFSLFYASDEDSLLSNTDLRDFQMAWNLVDKGRKGVMSVPQAKLFMRVYIFFKQNNFLKGRLDMD----NRTVPFRHMCCEIEKLRNGGD--VSFHDVLGIIAYRSVDISRS 1527

[Close]

BLAST of Voltage-dependent calcium channel vs. Ensembl Nematostella
Match: EDO35661 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SKR1])

HSP 1 Score: 167.933 bits (424), Expect = 1.420e-41
Identity = 185/658 (28.12%), Postives = 300/658 (45.59%), Query Frame = 2

Query: 3074 VMIFVTTTSCISMAFETPTKRVMNTIE--LKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMI-----LRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTKLKLSGDSPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEI-RDVIKAR------VGRINV---IYIHLFVFIGCLIGLTLFVGVVIANYSENKGT--------ALLTVDQRRWLD-LKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVL------LRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAM-FLLMLVYALAGIILFGSVKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFC--TYRENFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFI 4942
            +++F+   S IS+AFE        T++  L++   +F V  T+EM LK +  GF    K    +   +LDF I I+ I     M+ + TI      QI  I     LR  RPLR       M+ V+  L+     I  V ++ ++F   F++ GV IFGGK   C D    EK     V ++ + ++                W N  N NFD +    L L +V + EGW+EI  D + A       +   NV   ++  +F+ +G    L LF+GV+I N+++ K            LT  QR W++ LK             +PK R    QN                 K +  +YD+ Q   F+    + + IN + +     + D   +   +IL   N+ +T +F +E  L+I AL   GY+ +  N++D    F+ +I   + I V++   S V++ +   +  +      LRFF  A     ++ L+ ++++S   +LF I A+ FL++ +YA+ G+ +FG VK  E L    NF     S  LLFR++T   WN I+   M+  P C   YR      +CGN   + IY  SF ++I  I++N+ +A+I+EN++     ++  I +  DI  F Q W   D N   +I
Sbjct:  832 IILFLIAASSISLAFEDVYLDSKPTLKQVLQILNILFAVIFTVEMLLKWIGLGF----KTYFTNPWNILDFVIVIVSI-----MVSLATIFGND--QIAFIRSLRTLRAFRPLRAISRFEGMKVVITSLLHAIPGIGNVLLVCLMFWLIFSIMGVQIFGGKFGKCVD-EGGEKCPASVVPNKTVCLSN------------GYRWEN-SNINFDTVDQGFLALLQVATFEGWMEIMEDAVDATKIDEQPIEENNVSAYLFFVVFIILGTFFTLNLFIGVIIDNFNQLKQQMEAVGSMDVFLTSTQRNWMNALKSAAT--------KKPKKRIRRPQN-----------------KFQGELYDMVQSRKFEVFIMLFITINMVVMMV--QHYDHLAVWSKQIL---NLIFTSVFILEAILRIIALR-KGYFLNPWNVFD----FVIVISSIIGIIVENLQTSLVINPSLLRVVRVFRVGRLLRFFEAARG---IRRLLFSLVIST-PALFNIGALLFLIIFIYAIIGMSIFGHVKKTEALNDVVNFETFGSSFVLLFRLMTSAGWNDILDPLMISEPDCDPNYR-GLPSGNCGNKYMAPIYLGSFVVIIFLILINMYIAVILENYNQVMEQEKIGITN-EDIELFYQMWELFDPNATQYI 1423

HSP 2 Score: 77.411 bits (189), Expect = 6.612e-14
Identity = 132/609 (21.67%), Postives = 243/609 (39.90%), Query Frame = 2

Query:  692 LSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSM---KCVKIANSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLP------QWKGVS---YFISMIFFLAWLVKNVFIAILTETFAEIRVQFQQMWSPKNQTDADSSKIFQTDGQR-W--KLVPVYESKP--------HGLAPKLFQEIVLKSTAFNVIIMLLVLANAIVAAGLHFNHDELTQTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHCMWYRTQLTYF------------QVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEPKFD--RFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKI-PNDWAQQLFSTFSGIYFILINLIFSFAFMSMFQILTQKGWVIVMHDTMDMAKHRGLNALVAIYFVFYHLFVTLIVLSLFVAVILDNLELEEDIKKLKQLKLREMSAETQQKLPMRLRIFEKF-PNRPQMIKPARLLSDFL 2401
            ++ +RS R L   R LR+  +F   +  + ++LH +   + NV +  L F  +++I+GVQ FG                 K  D            + G+ CP S+   K V ++N    E     F T    F  + Q A+ EGW+ IM  A+D         +   VS   +F+  I    +   N+FI ++ + F +++ Q + +          S  +F T  QR W   L      KP        +    +L+   +++S  F V IML +  N +V    H++H  +          L+FT +F +EA+ +I  L  K Y+    + F+F++ + + +  +    Q +              +V R+ R  +A+  +    F +  S   L  +      ++ I + + + +F  ++  E   D   F  F  +F+ +F L+T  GW +++   MI      PN         + G+                                   + + G   +  IY   + + + LI++++++AVIL+N           Q+  +E    T + + +  +++E F PN  Q I P   LSDF+
Sbjct:  918 IAFIRSLRTLRAFRPLRAISRFEGMKVVITSLLH-AIPGIGNVLLVCLMFWLIFSIMGVQIFGGKFG-------------KCVD------------EGGEKCPASVVPNKTVCLSNGYRWENSNINFDTVDQGFLALLQVATFEGWMEIMEDAVDATKIDEQPIEENNVSAYLFFVVFIILGTFFTLNLFIGVIIDNFNQLKQQMEAV---------GSMDVFLTSTQRNWMNALKSAATKKPKKRIRRPQNKFQGELYD--MVQSRKFEVFIMLFITINMVVMMVQHYDHLAVWSKQ---ILNLIFTSVFILEAILRIIALR-KGYFLNPWNVFDFVIVISSIIGIIVENLQTSLVINPSLLRVVRVFRVGRLLRFFEAARGIRRLLFSLVISTPALFNIGALLFLIIFIYAIIGMSIFGHVKKTEALNDVVNFETFGSSFVLLFRLMTSAGWNDILDPLMISEPDCDPN---------YRGL----------------------------------PSGNCGNKYMAPIYLGSFVVIIFLILINMYIAVILEN---------YNQVMEQEKIGITNEDIELFYQMWELFDPNATQYI-PYADLSDFV 1432

HSP 3 Score: 71.633 bits (174), Expect = 3.033e-12
Identity = 87/353 (24.65%), Postives = 154/353 (43.63%), Query Frame = 2

Query: 2912 DKPLFTIGRESQFRQLCRMLVEAQYKPDINSENPEKQTFYKLQKFFGLVTYLDWVMIFVTTTSCISMAFETPTKRVMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKL-AICNDPTKTEKKDCVGVFDRKISVTKLK-----LSGDSPS--------FLVPRVWANPRNF---NFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVGRINVIYIHLFVFIGCLIGLTLFVGVVIANY-SENKGTALLTVDQRR 3916
             K L+  G E+  RQ    L+  QY   +++           +  F L+T L          +C+ +A   P ++          EY+F    TIEM  K++A GF     A +RD    LDF + I+  + ++       + + SG   +   R  R LR    V  ++ +V  L+   + +  V VL + F+  FA+ G+ +F G+L   C  P           +    S+  L+     L G++            +P    NP NF   +FD+ G A+LT F++++L+ W  + + +   +G   V+Y  + +F G    + L + VV A+Y +E K + + T ++R+
Sbjct:   21 SKSLYLFGPENPIRQFSLKLITNQYPLQLHN-----------RHMFVLLTIL---------VNCVFLAMTNPPEQ---------PEYVFAAIYTIEMFCKIIAKGFALHRYAYLRDKWNWLDFIVVILGNVTIS-----PDVANLSG---IPTFRVFRALRTISAVKGLKAMVNTLLVSMKMLWDVMVLTLFFICIFALIGMQLFIGELRNKCALPVPENLSVPYRTYASNSSIWYLEDNEPILCGNTTGSRTCPTNYTCLPHAGGNP-NFGYTSFDHFGWALLTGFQLITLDFWENVYNNVIYTMGPWYVVYFAVVIFFGPFFLVNLVLAVVAASYENEVKASKMETEEERK 335

HSP 4 Score: 62.7734 bits (151), Expect = 1.496e-9
Identity = 52/168 (30.95%), Postives = 92/168 (54.76%), Query Frame = 2

Query: 4208 NVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNHNSRV-MSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSM--FKSLFVIIAMFLLMLVYALAGIILFGSV----KYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMV 4690
            N  +TFIF +E  LK+ AL F+GY +   NI+D +V  +S++   V+  V D   + + +   F     LLR   +A    T+  L+ T+  S+    +L VI+A  +++ ++A+ G+ L G+     K+G ++ R  NF +   S  ++FR++ GE W + + DCM+
Sbjct:  539 NEVFTFIFLLEMILKLIALGFLGYIRVAWNIFDGIVVIISIVDFIVNKFVPDAGGTGISVLRTFR----LLRVLKLAKSWSTMNSLLATIGKSLGALGNLTVILA--IIVYIFAVMGMQLLGNSYTPDKFGGSIPRW-NFKDFPHSFMMIFRVLCGE-WIEPLWDCML 698

HSP 5 Score: 51.6026 bits (122), Expect = 3.933e-6
Identity = 64/297 (21.55%), Postives = 115/297 (38.72%), Query Frame = 2

Query:  386 DIVVALLFTAEMFTKMKIKGIIRPSPYVIVRHLFFVKVSNNIENKRPHAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFC----NPKFKSGD-----SCPYSMKCVKIANSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWLVKNVFIAILTETF 1249
            + V A ++T EMF K+  KG      + + R+                AYLR  W   D I+VI   ++I+     L  +                        T R      + R LR+    +  +  V  +L  S   +++V V  LFF+ ++A++G+Q F  ++ + C L       +     A   S      N     G+     +CP +  C+  A       GY  F  F ++  T +Q  + + W  +    +  +  W  V YF  +IFF  + + N+ +A++  ++
Sbjct:   77 EYVFAAIYTIEMFCKIIAKG------FALHRY----------------AYLRDKWNWLDFIVVILGNVTISPDVANLSGI-----------------------PTFR------VFRALRTISAVKGLKAMVNTLL-VSMKMLWDVMVLTLFFICIFALIGMQLFIGELRNKCALPVPENLSVPYRTYASNSSIWYLEDNEPILCGNTTGSRTCPTNYTCLPHAGG-NPNFGYTSFDHFGWALLTGFQLITLDFWENVYNNVIYTMGPWY-VVYFAVVIFFGPFFLVNLVLAVVAASY 319

[Close]

BLAST of Voltage-dependent calcium channel vs. Ensembl Nematostella
Match: EDO46991 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RNU9])

HSP 1 Score: 157.918 bits (398), Expect = 1.928e-38
Identity = 158/644 (24.53%), Postives = 297/644 (46.12%), Query Frame = 2

Query: 3074 VMIFVTT-TSCISMAFETPTKRVMNTI---ELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKL-AICND-----PTKTEKKDCVGVFDRKISVTKLKLSGDSPSFLVPRVWANPRNF---NFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVGRI-NVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVDQRR----------------WL----DLKGRIKLTQPLH--IPPRPKMRQ--------DSTQNRTDNNAINENSFDNRV---------IKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGS-VKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRENFWQSDCGNFQA-SLIYFCSFYIMITYIMLNVLVAIIMENFS 4840
            VMI +T   +C ++A   P     +++   EL+VAE++F    T+E  LK++A GF+  P A +R+   +LDF I ++ +  +  ++++ T  S   K  L   R LRPLR+   VP ++ V+  +++    +  +++L+V  +  +A+ GV +F GKL + C D     PT  E   C               S   P  +  + W  P N+   NFDNIG A LT+F+ ++LEGW ++   I   +G     +Y    +  G    L L +GV+   +++ K  A  + + ++                W+    D++G     +        +P  R+         + +N+ D+ A ++   D +          ++  C     TQ  Y+  +  + V +N + L     N  E+    ++ L   N  +  +F +E  +K+  L F GY+ S  N +D +V   SL+     + + +  + R +  +      LLR F +     +L  L+ ++L SM   + +++ + L M++++L G+ +FG     G+     +NF + +R++  +F+I+TGEDWN +M+  +            W     +  A  ++YF    ++  YI+LNV +AI ++N +
Sbjct:   78 VMILITIFANCAALAAFQPLPEQDSSLINEELEVAEFVFLGIFTMESVLKIIAYGFVMHPGAYLRNGWNILDFVIVVVGLATI--IVKLYTPDSFDVKA-LRAFRVLRPLRLVSGVPSLQVVLNSIIKALIPLFHIALLVVFVVIIYAIIGVELFMGKLHSTCYDNVTGQPTFDEPHPC------STESEGYSCSNAGPGQVCLKKWEGP-NYGITNFDNIGLACLTVFQCITLEGWTDVMYSINDAIGNSWPWLYFVTLIIWGSFFVLNLVLGVLSGEFAKEKARAQKSGEFQKLREKQLVDDAYHGYLDWISQAEDIEGDSSAGEDEEGKADRKPSFRRRKENDDISKNKENQEDSAASDQGWIDRKKKILKRFHHRLRRSCRKAVKTQWFYWTVI--VFVFLNSLTLALEHYNQPEF---LTQFLDKANKLFLALFTLEMVVKMYCLGFHGYFASLFNRFDCLVVISSLL----ELGLTEAMDQRPIGISMLRCVRLLRIFKVTRYWSSLSNLVASLLNSMRSIMGLLLLLSLFMVIFSLLGMQIFGGKFNLGDEDVPRSNFDSFWRALVTVFQILTGEDWNAVMYTGIQS----------WGGITESLSAIPILYFIFLVVVGNYILLNVFLAIAVDNLA 692

HSP 2 Score: 100.908 bits (250), Expect = 4.374e-21
Identity = 76/291 (26.12%), Postives = 143/291 (49.14%), Query Frame = 2

Query: 4130 NCIFLYFPWNNDDEYGMKRSKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFG--SVKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRENFWQSD----CGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFIKAF-YVRFLLRLIP 4981
            N I L   + N+ +     +++L  FN+ +T +F +EC LK+ A     Y+  + N++D    F+ ++   V I++ +  + ++ +  F  +   LR   +  +   +K L+ T + S     +V + + +   +YA+ G+ +FG  ++     + R+ NF    +S+ +LFR  TGE+W  IM  C    P      N +  D    CG    +  YFCSFY + +++++N+ VA+IM+NF   Y   + +I+  + +  F + W+  D    G +K    V  L R+ P
Sbjct: 1167 NTILLMMQYYNEPKL---YTRVLDGFNIGFTSVFLLECILKLFAFKPKNYFLDRWNLFD----FVVVVGSVVDITMNEVSSEQMFAFGFFRLFRALRLVKLLNQGSGIKTLLWTFIKSFQALPYVGLLIIMTFFIYAVVGMQMFGRIAIDPETQINRNNNFQTFPQSLMVLFRSATGENWQLIMLAC-TDTPNAKCDPNAYPQDTDGLCGT-DFAYAYFCSFYAICSFLIINLFVAVIMDNFD--YLTRDWSILGPHHLDEFVRVWSEYDPEASGCVKHVDIVTVLKRIAP 1446

HSP 3 Score: 97.8265 bits (242), Expect = 3.909e-20
Identity = 68/231 (29.44%), Postives = 114/231 (49.35%), Query Frame = 2

Query: 3062 YLDWVMIFVTTTSCISMAFETPTKRVMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTKLKLSGDSPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEI 3754
            +++++++ +  +SC+  A +           L   +Y F    TIE+ +K++A G I    +  R    +LDF +  + I+ +A     D+    S  +IL +LR LRPLR       ++ VV  +    + I  + ++ V+F F FAV GV +F G    C D  K  K++C G +       + K  G +   +  R W  P+ FNF+++  AMLTLF V++ EGW  I
Sbjct:  835 FVNFILLLIIVSSCMLAAEDPLNSNSKRNQVLNYFDYFFTAVFTIEITIKIIAYGVILHKGSFCRSAFNLLDFLVVAVSIVSIALR---DSSSQISVVRILRVLRVLRPLRAINRAKGLKHVVQCVFVAVKTIGNIMLVTVLFNFLFAVIGVQLFKGTFFSCTDAEKITKRECQGQY------IEFKGPGLTNPVVKDREW-QPQTFNFNDVPQAMLTLFTVMTFEGWPGI 1055

HSP 4 Score: 58.9214 bits (141), Expect = 2.299e-8
Identity = 60/254 (23.62%), Postives = 113/254 (44.49%), Query Frame = 2

Query:  524 PHAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANSIEDEG---GYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWLVKNVFIAILTETFAEIRVQFQQ 1276
            P AYLR+ W   D ++V+    +I         ++K  TP DS             L   R  RPL L   + S       Q  + +I+ ++   ++++ + ++F + +YAI+GV+ F   ++  C     N +     D   P S  +  +   ++ P  + C+K     + EG   G   F     +  TV+Q  + EGW  +MY   D +       YF+++I + ++ V N+ + +L+  FA+ + + Q+
Sbjct:  137 PGAYLRNGWNILDFVIVVVGLATI---------IVKLYTP-DSFD--------VKALRAFRVLRPLRLVSGVPSL------QVVLNSII-KALIPLFHIALLVVFVVIIYAIIGVELFMGKLHSTCY---DNVTGQPTFDEPHPCSTESEGYSCSNAGPGQV-CLK-----KWEGPNYGITNFDNIGLACLTVFQCITLEGWTDVMYSINDAIGNSWPWLYFVTLIIWGSFFVLNLVLGVLSGEFAKEKARAQK 356

HSP 5 Score: 52.7582 bits (125), Expect = 2.055e-6
Identity = 65/296 (21.96%), Postives = 125/296 (42.23%), Query Frame = 2

Query: 1409 VLKSTAFNVIIMLLVLANAIVAAGLHFNHDELTQTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVH-----CMWYR----TQLTYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEPKFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPNDWAQQLFSTFSGIYFILINLIFSFAFMSMFQILTQKGWVIVMHDTMDM--AKHRGLNALVAIYFVFYHLFVTLIVLSLFVAVILDNLELEEDI 2263
             +K+  F   +++ V  N++  A  H+N  E   T     A  +F  LF +E V K++CLG+  Y+    ++F+ ++ + + +       M  R    + L   ++LRIF++ +    L +    +  S + +  L+L  S  ++I S + +Q+F                       F L  E+     + R+  D+                          F  A +++FQILT + W  VM+  +         L+A+  +YF+F  +    I+L++F+A+ +DNL   E +
Sbjct:  454 AVKTQWFYWTVIVFVFLNSLTLALEHYNQPEFL-TQFLDKANKLFLALFTLEMVVKMYCLGFHGYFASLFNRFDCLVVISSLLELGLTEAMDQRPIGISMLRCVRLLRIFKVTRYWSSLSNLVASLLNSMRSIMGLLLLLSLFMVIFSLLGMQIFGGK--------------------FNLGDED-----VPRSNFDS--------------------------FWRALVTVFQILTGEDWNAVMYTGIQSWGGITESLSAIPILYFIFLVVVGNYILLNVFLAIAVDNLADAESL 697

[Close]

BLAST of Voltage-dependent calcium channel vs. Ensembl Nematostella
Match: EDO46797 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RP56])

HSP 1 Score: 145.976 bits (367), Expect = 8.656e-35
Identity = 154/631 (24.41%), Postives = 270/631 (42.79%), Query Frame = 2

Query: 3062 YLDWVMIFVTTTSCISMAFETPTKRVMNTIE--LKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKIS---VTKLKLSGDSPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEI-RDVIKA---------RVGRINVIYIHLFVFIGCLIGLTLFVGVVIANYSE--------NKGTALLTVDQRRWLDLKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVL-----LRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRENFW---QSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDE 4861
            Y +W ++F    S  ++ FE         +E  L    ++F    ++E  LKV+  GF+    +        LD  I  +C+  VA +     +   S  +    +R LRPLR    +  M+ V+  L      I  V V+ ++F   F++ GV +F GK              CV   D K+S   +       D P +     W N  N NFDN+ N  L L +V + EGW+E+  D + +             I   Y  +F+ +G    L LFVGV+I N++         N    LLT  QR+W+    +I +      PP  ++R          + ++ N F+  ++ V      +    ++ +     V+ N + +                           IF +E  +KI A+  + Y++   +I+D VV   S++ +++ +S +    S V+S   G + VL      R   +      ++ L+  +++SM     +   +FL+M +YA+ G+  FG++K    L    NF     SI L+FR+ TG  WN I+   +VQPP C    NF      +CG    ++ Y  ++ + +  I++N+ +A++++N +  + NDE
Sbjct:  794 YFEWFILFTVMVSSFTLVFEDIHLHQKPDLERALNFLNFLFAAIFSLEFILKVIGFGFV----SYFTSVWNCLDALIVSVCVS-VACLFENPNL---SVFRSFRTVRGLRPLRAISRLGGMKVVINALFAAIPGIGSVLVVSMLFWLMFSISGVQLFAGKF-----------YKCVNAEDEKLSPSVIPNKTACLDHPDYR----WVNA-NVNFDNVINGFLALLQVATYEGWMEVMADAVDSTKIDQQPSYEANLIAYAYFVVFIIVGSFFVLNLFVGVIIDNFNTLKKKYEEINSMGMLLTESQRKWV----QILMAAAKRKPPSNRLRPTDCFRGKLFDLVSSNQFEVFILTVIMCNMGMMMVQHYDQPPLTTVIGNYVLVG--------------------------IFLLEAIIKIIAMR-LHYFKKAWSIFDFVVVVSSIVGMYLGMSTE----SAVVSP--GLLRVLRVFRVARLLRVVQFAKRIRQLLVAIIISMPALFNIGTLLFLVMFIYAIIGMSSFGNIKKQGALNDLVNFETFSSSIILIFRLGTGTGWNDILDALVVQPPHCD--PNFGGLPNGNCGFPIGAVFYLVTYIVSVFLIIVNMYIAVLLDNVNRAHENDE 1361

HSP 2 Score: 70.0922 bits (170), Expect = 1.011e-11
Identity = 70/280 (25.00%), Postives = 124/280 (44.29%), Query Frame = 2

Query: 3062 YLDWVMIFVTTTSCISMAFETPTKRVMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKL---AICNDPTKTEKKDCVGVFDRKISVTKLKLS---GDSPS--FLVPRVWANPRN--FNFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVGRINVIYIHLFVFIGCLIGLTLFVGVVIANY 3871
            Y + ++  V   +CI +    P +          AEYIF    T+EM  K+++ GF+    A +RD    LD       ++F++Y+     I S SG   +  LR LR  R    +  +R +V  L+R  + +  V VL +  +   A+ G+ +F G+L    +      T   +    + R+        S   G  P+    V  V  NP +   NFD+IG +++  F++L+++ W  + D +   +G   ++Y  + +F      L L + VV  +Y
Sbjct:   62 YFEIIVTLVILVNCIILGLNDPPEE---------AEYIFTAIYTLEMICKIISRGFVKDSYAYLRDTWNWLDSL-----VVFLSYLSLAPDIASLSG---IRTLRVLRAFRTISALKGLRAMVNSLLRSLKLLTDVLVLFLFSLCVLALIGLQLFTGELRNKCVLETANATTINNPSSWYHREGEPLLCGFSSTAGRCPANYTCVAHVGPNPDHGFTNFDDIGWSLVMAFQILTMDFWENLYDRVLRSMGEWYMMYFVVGIFSCSFYLLNLVLAVVYMSY 324

HSP 3 Score: 60.4622 bits (145), Expect = 7.545e-9
Identity = 129/608 (21.22%), Postives = 242/608 (39.80%), Query Frame = 2

Query:  692 LSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPD-SFC--NPKFKSGDSCPYSMKCVKIANSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCL-----PQWKG----VSYFISMIFFLAWLVKNVFIAILTETFAEIRVQFQQMWSPKNQTDADSSKIFQTDGQR-WK--LVPVYESKP--HGLAP------KLFQEIVLKSTAFNVIIMLLVLANAIVAAGLHFNHDELTQTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHC-MWYRTQ-----------LTYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEPKFD--RFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKI-PNDWAQQLFSTFSGIYFILINLIFSFAFMSMFQILTQKGWVIVMHDTMDMAKHRGLNALVAIYFVFYHLFVTLIVLSLFVAVILDNLELEEDIKKLKQLKLREMSAETQQKLPMRLRIFEKFPNRPQMIKPARLLSDFL 2401
            LS  RS R +   R LR+  +    +  + A L  +   + +V V  + F  +++I GVQ F     + CV    N  D K++   IP+ + C  +P ++      +    V   N I               F  + Q A+ EGW+ +M  A+D       P ++      +YF+  I   ++ V N+F+ ++ + F  ++ +++++         +S  +  T+ QR W   L+   + KP  + L P      KLF   ++ S  F V I+ +++ N  +    H++   LT   G Y    V   +F +EA+ KI  +    Y+ ++   F+F++ + + V   +   T+           L  F+V R+ R+++ +  +      I  S   L  +      ++ I + + +  F +I+      D   F  F  + + IF L T  GW +++   ++      PN         F G    L N    F   ++F                              Y V Y + V LI++++++AV+LDN+    +  +            ++ K       F  F    Q + P R+L +FL
Sbjct:  882 LSVFRSFRTVRGLRPLRAISRLGGMKVVINA-LFAAIPGIGSVLVVSMLFWLMFSISGVQLFAGKF-YKCV----NAEDEKLSPSVIPNKTACLDHPDYR------WVNANVNFDNVIN-------------GFLALLQVATYEGWMEVMADAVDSTKIDQQPSYEANLIAYAYFVVFIIVGSFFVLNLFVGVIIDNFNTLKKKYEEI---------NSMGMLLTESQRKWVQILMAAAKRKPPSNRLRPTDCFRGKLFD--LVSSNQFEVFILTVIMCNMGMMMVQHYDQPPLTTVIGNY----VLVGIFLLEAIIKIIAMRLH-YFKKAWSIFDFVVVVSSIVGMYLGMSTESAVVSPGLLRVLRVFRVARLLRVVQFAKRIRQLLVAIIISMPALFNIGTLLFLVMFIYAIIGMSSFGNIKKQGALNDLVNFETFSSSIILIFRLGTGTGWNDILDALVVQPPHCDPN---------FGG----LPNGNCGFPIGAVF------------------------------YLVTYIVSVFLIIVNMYIAVLLDNVNRAHENDEF---------GLSKDKFKSYYHTFANFSMGKQFL-PLRVLPEFL 1395

HSP 4 Score: 59.3066 bits (142), Expect = 1.680e-8
Identity = 62/287 (21.60%), Postives = 118/287 (41.11%), Query Frame = 2

Query:  518 KRPHAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDS---------FCNPKFKSGDSCPYSMKCVKIANSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWLVKNVFIAILTETF-AEIRV------QFQQMWSPKNQTDADSSKIFQT 1330
            K  +AYLR  W   D+++V   ++S+                                +++L   R L + R  R+    +  +  V ++L RS   + +V V  LF + + A++G+Q F  ++ + CVL++AN + I       P S          C     +G  CP +  CV       D  G+  F    +S    +Q  + + W  +  R +  + +W  + YF+  IF  ++ + N+ +A++  ++  E+ +      Q Q   SP  Q+    S + Q+
Sbjct:  110 KDSYAYLRDTWNWLDSLVVFLSYLSLAPD-----------------------------IASLSGIRTLRVLRAFRTISALKGLRAMVNSLL-RSLKLLTDVLVLFLFSLCVLALIGLQLFTGELRNKCVLETANATTIN-----NPSSWYHREGEPLLCGFSSTAG-RCPANYTCVAHVGPNPDH-GFTNFDDIGWSLVMAFQILTMDFWENLYDRVLRSMGEWY-MMYFVVGIFSCSFYLLNLVLAVVYMSYHHEMNLTDNEVTQSQVTHSPVTQSQVTHSPVTQS 358

[Close]

BLAST of Voltage-dependent calcium channel vs. Ensembl Medaka
Match: nalcn (sodium leak channel, non-selective [Source:NCBI gene;Acc:101158897])

HSP 1 Score: 1457.97 bits (3773), Expect = 0.000e+0
Identity = 851/1872 (45.46%), Postives = 1165/1872 (62.23%), Query Frame = 2

Query:  164 ERKTSHTRETQPTLPGVEFATDDA-GDLTSVNWVYTTWARCAFKIXXXXXXXXXXXNTPETFKEYKWLFYVTYLLDIVVALLFTAEMFTKMKIKGIIRPSPYVIVRHLFFVKVSNNIENKRPHAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIA--NSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWLVKNVFIAILTETFAEIRVQFQQMWSPKNQTDADSS-KIFQTDGQR-WKLVPVYESKPHGLAPKLFQEIVLKSTAFNVIIMLLVLANAIVAAGLHF-NHDELTQTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHCM--WYRTQLTYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEPKFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPNDWAQQLFSTFSGIYFILINLIFSFAFMSMFQILTQKGWVIVMHDTMDMAKHRGLNALVAIYFVFYHLFVTLIVLSLFVAVILDNLELEEDIKKLKQLKLREMSAETQQKLPMRLRIFEKFPNRPQMIKPARLLSDFLIPKIRDSFMRQF------------AQLPTLEEENESDEMIAAAVSGVGVSSLPRALSIEIKRQIRGLKGN---DKLNAIIYLINESNKTRMIE-----QPIIYPTRSLLSTQHQIRTERRNLRNRMAATTMSINQKPRLNGEIRNMDFETNRKTEEANHFDIKILQQKAEQAEIKRNQQVDDLRENHPYFDKPLFTIGRESQFRQLCRMLVEAQY---KPDINSENPEKQTFYKLQKFFGLVTYLDWVMIFVTTTSCISMAFETPTKRVMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTK-----LKLSGDSPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVGRINVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVDQRRWLDLKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTY-RENFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFIKAFYVRF-LLRLIPKDRVGFDFTKKKDQQLFKEMCYEVELLRGGKDKEVSFHDVLTMLAYRSVDISKTXXXXXXXXXXXXXXXXXXXXXRQTIATWIERCIFRNR---QKHGDLKFGLRESNEMVIPIF------------DDKKEGLGLDRSRKISSGAYQTKFLSLPTLDG-RQNTSDGSLPSSGITIGRLNDHLKNQPMGFKRRRSVKKNSSTNQTLTE-------VSEDELNDELNDI 5596
            +RK S   E QP     +F  D+   D   + W+   W     +  A++S+ SV  NTP+TF+ Y  L YVT+ LD ++  L+TAEM  KM I+GII                      K  ++Y++  W  FD  MV  +W+S+ +Q FE+ K++   +P             +G+L   R PR LI+ R  R + +F LP++R+  IL RS  Q+++V++FLLFF+ LY ILGVQ FG   NHHCV     +  +    LAIPD+ C+P    G  CP+  KC+ +        E GY+GF     S FTVY+AASQEGWVF+MYRA+D  P+W+   YFI++IFFLAWLVKNVFIA++ ETFAEIRVQFQQMW  ++ T + ++ ++F  D    W+LV V  +KPHG AP   Q++ ++S+ F++ I+ +V  + IVAA  ++   +     + FY AE+ FT+LF++EA+ KIWCLG+  Y   SLHKFE +L +GTT+H     Y +Q TYFQVLR+ RL+K SP LEDF +KIFG GKKLG L++FT+ LLI+ S++SLQ+FC ++    + DR                                          F+TF              AFMSMFQILTQ+GW+ VM  T+ +A  R    +VAIYF+ YHLF TLI+LSLFVAVILDNLEL+ED+KKLKQLK  E +A+T++KLP+RLRIFEKFPNRPQM+K ++L SDF +P+IR+SFM+QF             +LP+    +  D    +A+         + +  +++R I   +     +K   I  ++    + RM+      QP     RS+LS QH IR ERR+LR+   +T+  I++   L    ++       +  +    +IK++Q+K EQAE+KR  Q ++LRENHPYFDKPLF +GRE +FR  CR++V A++   K D  +   +   +++L    GLVTYLDWVMI VT  SCISM FE+P  RVM    L++ EY+F + M+IE+ LK++A+G  FTP AV+RDFGGV+D FIY++ +IF+ ++     I   SG Q+LM+LRCLRPLRIF LVP MR+VV E+++GF+EI +VS+LL+  M  FA +GV +F GKLA CNDP+  +++DC G+F   +SV+K     LK     P F VPRVWANPRNFNFDN+GNAML LFEVLSL+GWVE+RDVI  RVG I+ IYIH+FVF+GC+IGLTLFVGVVIAN++ENKGTALLTVDQRRW DLK R+K+ QPLH+PPRP                 EN         R  +YD+TQH +FKR  A++VL   + L   W+ DD+        LA+ +V +TFIF +E  +K+ A+S  GYWQS+RN YD++VT L +IW+ +H S+ + +   +     G   ++ RFF+I GKHVTLKML+ TV++SM+KS F+I+ MFLL+L YA AG++LFG+VKYGEN+ RHANF    ++I +LFRIVTGEDWNKIMHDCMVQPPFCT  +  +W++DCGN+  +LIYFCSFY++I YIMLN+LVAII+ENFSLFYS +ED ++SYND+R+FQ  WN +D  R+G I    V+F L  L  +  V  D    KD+ LFK MCYE+E L  G D  V+FHDVL+ML+YRSVDI K+LQLEELLARE+LEY IEEEVA+QTI  W+++C+ R R   Q+   +   LRES +  +  F            +D       + S+   SG  Q    +L    G RQ++++   P   +   RL     +      +   V   +S+   + +       V  DE +D L DI
Sbjct:   28 KRKQSSRVEAQPM---TDFGPDETLADSADIFWINKPWVHSLLRACAIISVISVCMNTPKTFEHYPPLQYVTFTLDTLLMFLYTAEMIAKMHIRGII----------------------KGENSYVKDRWCMFDGFMVFFIWVSLVLQVFEIAKLVDQMSP-------------WGML---RIPRALIMIRAFRIYFRFELPRSRITNILKRSGEQIWSVSIFLLFFLLLYGILGVQMFGT-FNHHCVTNDTQKDHVTWNSLAIPDTHCSPD-GEGYQCPHGFKCMDLEELGLSRQELGYSGFNELGTSIFTVYEAASQEGWVFLMYRAIDSFPRWRSYFYFITLIFFLAWLVKNVFIAVIIETFAEIRVQFQQMWGSRSSTTSTATTQMFHEDAAGGWQLVAVDVNKPHGRAPACLQQM-MRSSVFHMFILSMVAVDVIVAASNYYKGENHRRHYDEFYLAEVAFTVLFDLEALLKIWCLGFTGYISSSLHKFESLLVMGTTLHIYPDLYHSQFTYFQVLRVVRLIKISPALEDFVYKIFGPGKKLGSLVVFTASLLIVMSAISLQMFCFVE----ELDR------------------------------------------FTTFPR------------AFMSMFQILTQEGWIDVMDQTL-VAVGRMWAPVVAIYFILYHLFATLILLSLFVAVILDNLELDEDLKKLKQLKQSEANADTKEKLPLRLRIFEKFPNRPQMVKISKLPSDFTVPRIRESFMKQFIDRQQQDTTCLFRRLPSASSSS-CDHSKRSAIED------NKYIDQKLRRSIFSFRARNLLEKETTINKILRACTRQRMLSGSFEGQPA--KERSILSVQHHIRQERRSLRH--GSTSQRISRGKSLETLTQDHSSTVRYRNAQREDSEIKMIQEKKEQAEMKRKVQEEELRENHPYFDKPLFIVGREHRFRNFCRVIVRARFNASKTDPLTGAVKNTKYHQLYDLLGLVTYLDWVMIVVTICSCISMMFESPFTRVMQVPTLQIGEYVFVIFMSIELNLKIMADGLFFTPTAVIRDFGGVMDIFIYLVSLIFLCWL--PPDIPPESGAQLLMMLRCLRPLRIFKLVPQMRKVVREVLKGFKEIFLVSILLLTLMLVFASFGVQLFAGKLAKCNDPSIIQREDCHGIFRINVSVSKNLNLKLKPGEKKPGFWVPRVWANPRNFNFDNVGNAMLALFEVLSLKGWVEVRDVIIHRVGPIHGIYIHVFVFLGCMIGLTLFVGVVIANFNENKGTALLTVDQRRWEDLKSRLKIAQPLHLPPRP-----------------ENG------GFRAKMYDITQHPFFKRGIAVLVLAQSVLLSVKWDVDDQVTFP----LATMSVVFTFIFVLEVTMKLIAMSPAGYWQSRRNRYDLLVTSLGVIWIVLHFSLLNAYTYMM-----GTCVIVFRFFTICGKHVTLKMLLLTVVVSMYKSFFIIVGMFLLLLCYAFAGVVLFGTVKYGENINRHANFSTAGKAITVLFRIVTGEDWNKIMHDCMVQPPFCTPDKHRYWETDCGNYAGALIYFCSFYVIIAYIMLNLLVAIIVENFSLFYSTEEDQLLSYNDLRHFQIIWNMVDDKREGVIPTSRVKFLLRLLRGRLEVDLD----KDKLLFKHMCYEMERLHSGGD--VTFHDVLSMLSYRSVDIRKSLQLEELLAREQLEYTIEEEVAKQTIRMWLKKCLKRIRAKQQQSCSIIHSLRESQQQELNRFLNPPSIETTVPSEDHNTNNADNPSQPEMSGLQQLLSPTLSDRGGYRQDSTELGRPQRKLGQWRLPAGRTSVKSIVCKMNPVNDEASSGSEVKKWWTRQLTVESDESDDNLIDI 1745

[Close]

BLAST of Voltage-dependent calcium channel vs. Ensembl Medaka
Match: nalcn (sodium leak channel, non-selective [Source:NCBI gene;Acc:101158897])

HSP 1 Score: 1457.2 bits (3771), Expect = 0.000e+0
Identity = 851/1872 (45.46%), Postives = 1165/1872 (62.23%), Query Frame = 2

Query:  164 ERKTSHTRETQPTLPGVEFATDDA-GDLTSVNWVYTTWARCAFKIXXXXXXXXXXXNTPETFKEYKWLFYVTYLLDIVVALLFTAEMFTKMKIKGIIRPSPYVIVRHLFFVKVSNNIENKRPHAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIA--NSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWLVKNVFIAILTETFAEIRVQFQQMWSPKNQTDADSS-KIFQTDGQR-WKLVPVYESKPHGLAPKLFQEIVLKSTAFNVIIMLLVLANAIVAAGLHF-NHDELTQTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHCM--WYRTQLTYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEPKFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPNDWAQQLFSTFSGIYFILINLIFSFAFMSMFQILTQKGWVIVMHDTMDMAKHRGLNALVAIYFVFYHLFVTLIVLSLFVAVILDNLELEEDIKKLKQLKLREMSAETQQKLPMRLRIFEKFPNRPQMIKPARLLSDFLIPKIRDSFMRQF------------AQLPTLEEENESDEMIAAAVSGVGVSSLPRALSIEIKRQIRGLKGN---DKLNAIIYLINESNKTRMIE-----QPIIYPTRSLLSTQHQIRTERRNLRNRMAATTMSINQKPRLNGEIRNMDFETNRKTEEANHFDIKILQQKAEQAEIKRNQQVDDLRENHPYFDKPLFTIGRESQFRQLCRMLVEAQY---KPDINSENPEKQTFYKLQKFFGLVTYLDWVMIFVTTTSCISMAFETPTKRVMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTK-----LKLSGDSPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVGRINVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVDQRRWLDLKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTY-RENFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFIKAFYVRF-LLRLIPKDRVGFDFTKKKDQQLFKEMCYEVELLRGGKDKEVSFHDVLTMLAYRSVDISKTXXXXXXXXXXXXXXXXXXXXXRQTIATWIERCIFRNR---QKHGDLKFGLRESNEMVIPIF------------DDKKEGLGLDRSRKISSGAYQTKFLSLPTLDG-RQNTSDGSLPSSGITIGRLNDHLKNQPMGFKRRRSVKKNSSTNQTLTE-------VSEDELNDELNDI 5596
            +RK S   E QP     +F  D+   D   + W+   W     +  A++S+ SV  NTP+TF+ Y  L YVT+ LD ++  L+TAEM  KM I+GII                      K  ++Y++  W  FD  MV  +W+S+ +Q FE+ K++   +P             +G+L   R PR LI+ R  R + +F LP++R+  IL RS  Q+++V++FLLFF+ LY ILGVQ FG   NHHCV     +  +    LAIPD+ C+P    G  CP+  KC+ +        E GY+GF     S FTVY+AASQEGWVF+MYRA+D  P+W+   YFI++IFFLAWLVKNVFIA++ ETFAEIRVQFQQMW  ++ T + ++ ++F  D    W+LV V  +KPHG AP   Q++ ++S+ F++ I+ +V  + IVAA  ++   +     + FY AE+ FT+LF++EA+ KIWCLG+  Y   SLHKFE +L +GTT+H     Y +Q TYFQVLR+ RL+K SP LEDF +KIFG GKKLG L++FT+ LLI+ S++SLQ+FC ++    + DR                                          F+TF              AFMSMFQILTQ+GW+ VM  T+ +A  R    +VAIYF+ YHLF TLI+LSLFVAVILDNLEL+ED+KKLKQLK  E +A+T++KLP+RLRIFEKFPNRPQM+K ++L SDF +P+IR+SFM+QF             +LP+    +  D    +A+         + +  +++R I   +     +K   I  ++    + RM+      QP     RS+LS QH IR ERR+LR+   +T+  I++   L    ++       +  +    +IK++Q+K EQAE+KR  Q ++LRENHPYFDKPLF +GRE +FR  CR++V A++   K D  +   +   +++L    GLVTYLDWVMI VT  SCISM FE+P  RVM    L++ EY+F + M+IE+ LK++A+G  FTP AV+RDFGGV+D FIY++ +IF+ ++     I   SG Q+LM+LRCLRPLRIF LVP MR+VV E+++GF+EI +VS+LL+  M  FA +GV +F GKLA CNDP+  +++DC G+F   +SV+K     LK     P F VPRVWANPRNFNFDN+GNAML LFEVLSL+GWVE+RDVI  RVG I+ IYIH+FVF+GC+IGLTLFVGVVIAN++ENKGTALLTVDQRRW DLK R+K+ QPLH+PPRP                 EN         R  +YD+TQH +FKR  A++VL   + L   W+ DD+        LA+ +V +TFIF +E  +K+ A+S  GYWQS+RN YD++VT L +IW+ +H S+ + +   +     G   ++ RFF+I GKHVTLKML+ TV++SM+KS F+I+ MFLL+L YA AG++LFG+VKYGEN+ RHANF    ++I +LFRIVTGEDWNKIMHDCMVQPPFCT  +  +W++DCGN+  +LIYFCSFY++I YIMLN+LVAII+ENFSLFYS +ED ++SYND+R+FQ  WN +D  R+G I    V+F L  L  +  V  D    KD+ LFK MCYE+E L  G D  V+FHDVL+ML+YRSVDI K+LQLEELLARE+LEY IEEEVA+QTI  W+++C+ R R   Q+   +   LRES +  +  F            +D       + S+   SG  Q    +L    G RQ++++   P   +   RL     +      +   V   +S+   + +       V  DE +D L DI
Sbjct:   23 KRKQSSRVEAQPM---TDFGPDETLADSADIFWINKPWVHSLLRACAIISVISVCMNTPKTFEHYPPLQYVTFTLDTLLMFLYTAEMIAKMHIRGII----------------------KGENSYVKDRWCMFDGFMVFFIWVSLVLQVFEIAKLVDQMSP-------------WGML---RIPRALIMIRAFRIYFRFELPRSRITNILKRSGEQIWSVSIFLLFFLLLYGILGVQMFGT-FNHHCVTNDTQKDHVTWNSLAIPDTHCSPD-GEGYQCPHGFKCMDLEELGLSRQELGYSGFNELGTSIFTVYEAASQEGWVFLMYRAIDSFPRWRSYFYFITLIFFLAWLVKNVFIAVIIETFAEIRVQFQQMWGSRSSTTSTATTQMFHEDAAGGWQLVAVDVNKPHGRAPACLQQM-MRSSVFHMFILSMVAVDVIVAASNYYKGENHRRHYDEFYLAEVAFTVLFDLEALLKIWCLGFTGYISSSLHKFESLLVMGTTLHIYPDLYHSQFTYFQVLRVVRLIKISPALEDFVYKIFGPGKKLGSLVVFTASLLIVMSAISLQMFCFVE----ELDR------------------------------------------FTTFPR------------AFMSMFQILTQEGWIDVMDQTL-VAVGRMWAPVVAIYFILYHLFATLILLSLFVAVILDNLELDEDLKKLKQLKQSEANADTKEKLPLRLRIFEKFPNRPQMVKISKLPSDFTVPRIRESFMKQFIDRQQQDTTCLFRRLPSASSSS-CDHSKRSAIED------NKYIDQKLRRSIFSFRARNLLEKETTINKILRACTRQRMLSGSFEGQPA--KERSILSVQHHIRQERRSLRH--GSTSQRISRGKSLETLTQDHSSTVRYRNAQREDSEIKMIQEKKEQAEMKRKVQEEELRENHPYFDKPLFIVGREHRFRNFCRVIVRARFNASKTDPLTGAVKNTKYHQLYDLLGLVTYLDWVMIVVTICSCISMMFESPFTRVMQVPTLQIGEYVFVIFMSIELNLKIMADGLFFTPTAVIRDFGGVMDIFIYLVSLIFLCWL--PPDIPPESGAQLLMMLRCLRPLRIFKLVPQMRKVVREVLKGFKEIFLVSILLLTLMLVFASFGVQLFAGKLAKCNDPSIIQREDCHGIFRINVSVSKNLNLKLKPGEKKPGFWVPRVWANPRNFNFDNVGNAMLALFEVLSLKGWVEVRDVIIHRVGPIHGIYIHVFVFLGCMIGLTLFVGVVIANFNENKGTALLTVDQRRWEDLKSRLKIAQPLHLPPRP-----------------ENG------GFRAKMYDITQHPFFKRGIAVLVLAQSVLLSVKWDVDDQVTFP----LATMSVVFTFIFVLEVTMKLIAMSPAGYWQSRRNRYDLLVTSLGVIWIVLHFSLLNAYTYMM-----GTCVIVFRFFTICGKHVTLKMLLLTVVVSMYKSFFIIVGMFLLLLCYAFAGVVLFGTVKYGENINRHANFSTAGKAITVLFRIVTGEDWNKIMHDCMVQPPFCTPDKHRYWETDCGNYAGALIYFCSFYVIIAYIMLNLLVAIIVENFSLFYSTEEDQLLSYNDLRHFQIIWNMVDDKREGVIPTSRVKFLLRLLRGRLEVDLD----KDKLLFKHMCYEMERLHSGGD--VTFHDVLSMLSYRSVDIRKSLQLEELLAREQLEYTIEEEVAKQTIRMWLKKCLKRIRAKQQQSCSIIHSLRESQQQELNRFLNPPSIETTVPSEDHNTNNADNPSQPEMSGLQQLLSPTLSDRGGYRQDSTELGRPQRKLGQWRLPAGRTSVKSIVCKMNPVNDEASSGSEVKKWWTRQLTVESDESDDNLIDI 1740

[Close]

BLAST of Voltage-dependent calcium channel vs. Ensembl Medaka
Match: nalcn (sodium leak channel, non-selective [Source:NCBI gene;Acc:101158897])

HSP 1 Score: 1419.45 bits (3673), Expect = 0.000e+0
Identity = 848/1886 (44.96%), Postives = 1154/1886 (61.19%), Query Frame = 2

Query:  164 ERKTSHTRETQPTLPGVEFATDDA-GDLTSVNWVYTTWARCAFKIXXXXXXXXXXXNTPETFKEYKWLFYVTYLLDIVVALLFTAEMFTKMKIKGIIRPSPYVIVRHLFFVKVSNNIENKRPHAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIA--NSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWLVKNVFIAILTETFAEIRVQFQQMWSPKNQTDADSS-KIFQTDGQR-WKLVPVYESKPHGLAPKLFQEIVLKSTAFNVIIMLLVLANAIVAAGLHF-NHDELTQTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHCM--WYRTQLTYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEPKFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPNDWAQQLFSTFSGIYFILINLIFSFAFMSMFQILTQKGWVIVMHDTMDMAKHRGLNALVAIYFVFYHLFVTLIVLSLFVAVILDNLELEEDIKKLKQLKLREMSAETQQKLPMRLRIFEKFPNRPQMIKPARLLSDFLIPKIRDSFMRQF------------AQLPTLEEENESDEMIAAAVSGVGVSSLPRALSIEIKRQIRGLKGN---DKLNAIIYLINESNKTRMIE-----QPIIYPTRSLLSTQHQIRTERRNLRNRMAATTMSINQKPRLNGEIRNMDFETNRKTEEANHFDIKILQQKAEQAEIK-RNQQVDDLRENHPYFDKPLFTIGRESQFRQLCRMLVEAQY---KPDINSENPEKQTFYKLQKFFGLVTYLDWVMIFVTTTSCISMAFETPTKRVMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTK-----LKLSGDSPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVGRINVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVDQRRWLDLKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKYGENLGR-HANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTY-RENFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFIKAFYVRF-LLRLIPKDRVGFDFTKKKDQQLFKEMCYEVELLRGGKDKEVSFHDVLTMLAYRSVDISKTXXXXXXXXXXXXXXXXXXXXXRQTIATWIERCIFRNR---QKHGDLKFGLRESNEMVIPIF------------DDKKEGLGLDRSRKISSGAYQTKFLSLPTLDG-RQNTSDGSLPSSGITIGRLNDHLKNQPMGF--KRRRSVK----KNSSTNQTLTEVSE-------------DELNDELNDI 5596
            +RK S   E QP     +F  D+   D   + W+   W     +  A++S+ SV  NTP+TF+ Y  L YVT+ LD ++  L+TAEM  KM I+GII                      K  ++Y++  W  FD  MV  +W+S+ +Q FE+ K++   +P             +G+L   R PR LI+ R  R + +F LP++R+  IL RS  Q+++V++FLLFF+ LY ILGVQ FG   NHHCV     +  +    LAIPD+ C+P    G  CP+  KC+ +        E GY+GF     S FTVY+AASQEGWVF+MYRA+D  P+W+   YFI++IFFLAWLVKNVFIA++ ETFAEIRVQFQQMW  ++ T + ++ ++F  D    W+LV V  +KPHG AP   Q++ ++S+ F++ I+ +V  + IVAA  ++   +     + FY AE+ FT+LF++EA+ KIWCLG+  Y   SLHKFE +L +GTT+H     Y +Q TYFQVLR+ RL+K SP LEDF +KIFG GKKLG L++FT+ LLI+ S++SLQ+FC ++    + DR                                          F+TF              AFMSMFQILTQ+GW+ VM  T+ +A  R    +VAIYF+ YHLF TLI+LSLFVAVILDNLEL+ED+KKLKQLK  E +A+T++KLP+RLRIFEKFPNRPQM+K ++L SDF +P+IR+SFM+QF             +LP+    +  D    +A+         + +  +++R I   +     +K   I  ++    + RM+      QP     RS+LS QH IR ERR+LR+   +T+  I++   L    ++       +  +    +IK++Q+K EQAE+K R  Q ++LRENHPYFDKPLF +GRE +FR  CR++V A++   K D  +   +   +++L    GLVTYLDWVMI VT  SCISM FE+P  RVM    L++ EY+F + M+IE+ LK++A+G  FTP AV+RDFGGV+D FIY++ +IF+ ++     I   SG Q+LM+LRCLRPLRIF LVP MR+VV E+++GF+EI +VS+LL+  M  FA +GV +F GKLA CNDP+  +++DC G+F   +SV+K     LK     P F VPRVWANPRNFNFDN+GNAML LFEVLSL+GWVE+RDVI  RVG I+ IYIH+FVF+GC+IGLTLFVGVVIAN++ENKGTALLTVDQRRW DLK R+K+ QPLH+PPRP                 EN         R  +YD+TQH +FKR  A++VL   + L                              ++  +K+ A+S  GYWQS+RN YD++VT L +IW+ +H S+ + +   +     G   ++ RFF+I GKHVTLKML+ TV++SM+KS F+I+ MFLL+L YA AG++LFG+VKYGEN+ R HANF    ++I +LFRIVTGEDWNKIMHDCMVQPPFCT  +  +W++DCGN+  +LIYFCSFY++I YIMLN+LVAII+ENFSLFYS +ED ++SYND+R+FQ  WN +D  R+G I    V+F L  L  +  V  D    KD+ LFK MCYE+E L  G D  V+FHDVL+ML+YRSVDI K+LQLEELLARE+LEY IEEEVA+QTI  W+++C+ R R   Q+   +   LRES +  +  F            +D       + S+   SG  Q    +L    G RQ++++   P   +   RL       P GF    R SVK    K +  N   +  SE             DE +D L DI
Sbjct:    3 KRKQSSRVEAQPM---TDFGPDETLADSADIFWINKPWVHSLLRACAIISVISVCMNTPKTFEHYPPLQYVTFTLDTLLMFLYTAEMIAKMHIRGII----------------------KGENSYVKDRWCMFDGFMVFFIWVSLVLQVFEIAKLVDQMSP-------------WGML---RIPRALIMIRAFRIYFRFELPRSRITNILKRSGEQIWSVSIFLLFFLLLYGILGVQMFGT-FNHHCVTNDTQKDHVTWNSLAIPDTHCSPD-GEGYQCPHGFKCMDLEELGLSRQELGYSGFNELGTSIFTVYEAASQEGWVFLMYRAIDSFPRWRSYFYFITLIFFLAWLVKNVFIAVIIETFAEIRVQFQQMWGSRSSTTSTATTQMFHEDAAGGWQLVAVDVNKPHGRAPACLQQM-MRSSVFHMFILSMVAVDVIVAASNYYKGENHRRHYDEFYLAEVAFTVLFDLEALLKIWCLGFTGYISSSLHKFESLLVMGTTLHIYPDLYHSQFTYFQVLRVVRLIKISPALEDFVYKIFGPGKKLGSLVVFTASLLIVMSAISLQMFCFVE----ELDR------------------------------------------FTTFPR------------AFMSMFQILTQEGWIDVMDQTL-VAVGRMWAPVVAIYFILYHLFATLILLSLFVAVILDNLELDEDLKKLKQLKQSEANADTKEKLPLRLRIFEKFPNRPQMVKISKLPSDFTVPRIRESFMKQFIDRQQQDTTCLFRRLPSASSSS-CDHSKRSAIED------NKYIDQKLRRSIFSFRARNLLEKETTINKILRACTRQRMLSGSFEGQPA--KERSILSVQHHIRQERRSLRH--GSTSQRISRGKSLETLTQDHSSTVRYRNAQREDSEIKMIQEKKEQAEMKSRKVQEEELRENHPYFDKPLFIVGREHRFRNFCRVIVRARFNASKTDPLTGAVKNTKYHQLYDLLGLVTYLDWVMIVVTICSCISMMFESPFTRVMQVPTLQIGEYVFVIFMSIELNLKIMADGLFFTPTAVIRDFGGVMDIFIYLVSLIFLCWL--PPDIPPESGAQLLMMLRCLRPLRIFKLVPQMRKVVREVLKGFKEIFLVSILLLTLMLVFASFGVQLFAGKLAKCNDPSIIQREDCHGIFRINVSVSKNLNLKLKPGEKKPGFWVPRVWANPRNFNFDNVGNAMLALFEVLSLKGWVEVRDVIIHRVGPIHGIYIHVFVFLGCMIGLTLFVGVVIANFNENKGTALLTVDQRRWEDLKSRLKIAQPLHLPPRP-----------------ENG------GFRAKMYDITQHPFFKRGIAVLVLAQSVLL-----------------------------SVKVTMKLIAMSPAGYWQSRRNRYDLLVTSLGVIWIVLHFSLLNAYTYMM-----GTCVIVFRFFTICGKHVTLKMLLLTVVVSMYKSFFIIVGMFLLLLCYAFAGVVLFGTVKYGENINRLHANFSTAGKAITVLFRIVTGEDWNKIMHDCMVQPPFCTPDKHRYWETDCGNYAGALIYFCSFYVIIAYIMLNLLVAIIVENFSLFYSTEEDQLLSYNDLRHFQIIWNMVDDKREGVIPTSRVKFLLRLLRGRLEVDLD----KDKLLFKHMCYEMERLHSGGD--VTFHDVLSMLSYRSVDIRKSLQLEELLAREQLEYTIEEEVAKQTIRMWLKKCLKRIRAKQQQSCSIIHSLRESQQQELNRFLNPPSIETTVPSEDHNTNNADNPSQPEMSGLQQLLSPTLSDRGGYRQDSTELGRPQRKLGQWRL-------PAGFVLSGRTSVKSIVCKMNPVNDEASSGSEVKKWWTRQLTVESDESDDNLIDI 1702

[Close]

BLAST of Voltage-dependent calcium channel vs. Ensembl Medaka
Match: cacna1c (voltage-dependent L-type calcium channel subunit alpha-1C [Source:NCBI gene;Acc:101173517])

HSP 1 Score: 173.711 bits (439), Expect = 9.608e-43
Identity = 174/664 (26.20%), Postives = 296/664 (44.58%), Query Frame = 2

Query: 3074 VMIFVTTTSCISMAFETPTKR--VMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLAICNDPTKTEKKDCVG--VFDRKISVTKLKLSGDSPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEI-RDVIKARVGRINVIYIHLFVFIGCLIG---------LTLFVGVVIANYSENK----GTALLTVDQRRWLD--LKGRIKLTQPL--HIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHI--SVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKYGE--NLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPF---CTYRENFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFIKAFYVRFLLRLI 4978
            +++F    S IS+A E P K     N I L  A+++F    TIE+ LK+ A G      +  R++  +LD  +  + +I          +      +IL +LR LRPLR       ++ VV  +    R I  + ++  +  F FA  GV +F GK   C D +K  + +C G  +  +   V K   S        PRVW N  +FNFD++   M+ LF V + EGW  +    I +    +  IY +  V     I          + +FVG VI  + E          L  +QR+ ++  LK R     PL  +IP  P   +                           V+ +    YF+ +   ++L+N I L    +   +       IL   N+ +T +F +E  LK+ A    GY+    N++D ++   S+I V +     +Q++  +  +S  F  +  ++R   +  +   ++ L+ T + S     +V + + +L  +YA+ G+ +FG +   +   + R+ NF    +++ LLFR  TGE W +IM  C    P     T   +    +CG+ Q ++IYF SFY++  ++++N+ VA+IM+NF   Y   + +I+  + +  F++ W   D   KG IK   V  LLR I
Sbjct:  940 LILFFILLSSISLAAEDPVKNDSFRNQI-LGYADHVFTGLFTIEIILKMTAYGAFLHKGSFCRNYFNILDLVVVSVSLISSGIQSSAINV-----VKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKFFYCTDSSKQTQAECRGSYIMYKDGDVGKPGRS--------PRVWEN-SDFNFDDVLQGMMALFAVSTFEGWPGLLYRAIDSHSEDVGPIYNYRVVISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKAR-----PLRRYIPKNPYQYK---------------------------VWYVVNSTYFEYLMFTLILLNTICLAMQHHGQTKNFNDAMNIL---NMLFTGLFTVEMILKLIAFKPRGYFSDPWNVFDFLIVIGSIIDVILSEINGLQNSEENARISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMFGKIALRDLSQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACSPNRPCEKGSTNENSTASEECGS-QFAIIYFVSFYMLCAFLIINLFVAVIMDNFD--YLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRI 1550

HSP 2 Score: 120.939 bits (302), Expect = 1.148e-26
Identity = 165/673 (24.52%), Postives = 299/673 (44.43%), Query Frame = 2

Query: 3056 VTYLDW----VMIFVTT-TSCISMAFETP----TKRVMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGS----GK------QILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKL-AIC-------NDPTKTEKKDCVGVFDRKISVTKLKLSGDSPSFLVPRV-WANPRN--FNFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVG-RINVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVD-------QRRWLDLKGRIK-LTQPLHIPP----------RPK-MRQDSTQNR---TDNNA----------------INENSFD------NRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYD-MVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRENFWQSDCGNFQASL--IYFCSFYIMITYIMLNVLVAIIMENFS 4840
            ++ ++W    ++I +T   +C+++A   P         N+  L+  EY+F +  T+E  LKV+A G +F P A +R+   +LDF I ++ +   + ++   T G G+    GK      + L   R LRPLR+   VP ++ V+  +++    +L +++L++  +  +A+ G+ +F GK+   C       N   K       G + R  +    +           RV W  P +   NFDN   AMLT+F+ +++EGW ++   +   V  R   +Y    + IG    L L +GV+   +S+ +  A    D       Q+   DLKG +  +TQ   I P          +P+ +   +++N    TDN                  I+++ F       NR+ + +C     +Q  Y+  +   +V +N + +    +   ++      I    N     +F  E  LK+ +L    Y+ S  N +D  VV    L  + V   +       V+         LLR F I     +L  L+ ++L S+     +++ +FL +++++L G+ LFG  K+  +  R + F N  +S+  +F+I+TGEDWN +M+D ++                 +F   L  IYF   +I   YI+LNV +AI ++N +
Sbjct:  157 ISIVEWKPFEIIILMTIFANCVALAVYIPFPEDDSNATNS-NLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLF--SAILEQATKGDGATPIGGKAAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCVHNHTGLNAEEKPAPCAPDGAYGRHCTQNGTQC----------RVGWEGPNDGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAVDYRWPWVYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEEEGLDDDKPRNLSMPASENESVNTDNPPGGDVEGETCCTRLAIRISKSKFSRYSRRWNRLFRRKCRAAVKSQVFYWLVI--FLVFLNTLTIASEHHRQPQWLTDVQDIA---NKVLLALFTGEMLLKMYSLGLQAYFVSLFNRFDSFVVCGGILETILVETKIMSPLGISVLR-----CVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGG-KFNFDETRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIM------------AYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLA 793

HSP 3 Score: 92.8189 bits (229), Expect = 3.925e-18
Identity = 139/601 (23.13%), Postives = 244/601 (40.60%), Query Frame = 2

Query:  524 PHAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTR-------VLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLP-QWKGVSYFISMIFFLAWLVKNVFIAILTETF------AEIRVQFQQMWSPKNQTDAD------------------SSKIFQTDGQRWKLVPVYESK-------PHG----------LA---------------PKLFQE---IVLKSTAFNVIIMLLVLANAIVAAGLHFNHDE-LTQTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFE-FILCLG--------TTVHCMWYRTQLTYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCS-IQIYEPKFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPNDWAQQLFSTFSG----IYFILINLIFSFAFMSMF 2080
            P+AYLR+ W   D I+V+    S  ++     +  K +       +   F  K   L   R  RPL L         VL S +K  +P      +LH        + + +LF + +YAI+G++ F   ++  CV    N + +   +   P   C P    G  C  +    ++     ++G    F  F F+  TV+Q  + EGW  ++Y   D +  +W  V YF+++I   ++ V N+ + +L+  F      A+ R  FQ++   K Q + D                    +    D  R   +P  E++       P G          LA                +LF+      +KS  F  +++ LV  N +  A  H    + LT       A  V   LF  E + K++ LG ++Y+    ++F+ F++C G        T +      + L   ++LRIF++ +    L +    +  S + +  L+L     +II S + +QLF       E +   F NFP++ L +F ++T E W  VM   ++ A   P         +F G    IYFI++ +  ++  +++F
Sbjct:  226 PNAYLRNGWNLLDFIIVVVGLFSAILE-----QATKGDGATPIGGKAAGFDVK--ALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVP------LLH--------IALLVLFVIIIYAIIGLELFMGKMHKTCV---HNHTGLNAEEKPAP---CAPDGAYGRHCTQNGTQCRVGWEGPNDG-ITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAVDYRWPWV-YFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLRE-KQQLEEDLKGYLDWITQAEDIDPENEEEGLDDDKPRNLSMPASENESVNTDNPPGGDVEGETCCTRLAIRISKSKFSRYSRRWNRLFRRKCRAAVKSQVFYWLVIFLVFLNTLTIASEHHRQPQWLTDVQDI--ANKVLLALFTGEMLLKMYSLGLQAYFVSLFNRFDSFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIM-AYGGP---------SFPGMLVCIYFIILFICGNYILLNVF 784

HSP 4 Score: 69.3218 bits (168), Expect = 4.548e-11
Identity = 81/373 (21.72%), Postives = 154/373 (41.29%), Query Frame = 2

Query: 1079 SFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWL---------VKNVFIAILTETFAEIRVQ-FQQMWSPKNQTDADSSKIFQTDGQRWKLVPVYESKPHGLAPKLFQEIVLKSTAFNVIIMLLVLANAIVAAGLHFNHDELTQTNGFYYA----ELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHCMW------------YRTQLTYFQVLRIFRLMK---ASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYE----PKFDRFSNFPKAFLQIFTLVTEEGWIEVM-----TRAMIDAKKIPNDWA-QQLFSTFSGIYFILINLIFSFAFMSMF 2080
                ++  ++ EGW  ++YRA+D   +  G  Y   ++  + ++         + N+F+  +  TF E   Q ++     KNQ       +     +R+     Y+ K            V+ ST F  ++  L+L N I  A  H       QT  F  A     ++FT LF +E + K+     + Y+    + F+F++ +G+ +  +              R  +T+F++ R+ RL+K       +    +    S + L  + L    L  I + + +Q+F  I + +     + + F  FP+A L +F   T E W E+M      R         N  A ++  S F+ IYF+   ++ +F  +++F
Sbjct: 1139 GMMALFAVSTFEGWPGLLYRAIDSHSEDVGPIYNYRVVISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNPYQYK---------VWYVVNSTYFEYLMFTLILLNTICLAMQHHG-----QTKNFNDAMNILNMLFTGLFTVEMILKLIAFKPRGYFSDPWNVFDFLIVIGSIIDVILSEINGLQNSEENARISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMFGKIALRDLSQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACSPNRPCEKGSTNENSTASEECGSQFAIIYFVSFYMLCAFLIINLF 1497

[Close]

BLAST of Voltage-dependent calcium channel vs. Ensembl Medaka
Match: cacna1c (voltage-dependent L-type calcium channel subunit alpha-1C [Source:NCBI gene;Acc:101173517])

HSP 1 Score: 172.94 bits (437), Expect = 1.470e-42
Identity = 177/662 (26.74%), Postives = 296/662 (44.71%), Query Frame = 2

Query: 3074 VMIFVTTTSCISMAFETPTKR--VMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLAICNDPTKTEKKDCVG--VFDRKISVTKLKLSGDSPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEI-RDVIKARVGRINVIYIHLFVFIGCLIG---------LTLFVGVVIANYSENK----GTALLTVDQRRWLD--LKGRIKLTQPL--HIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKYGE--NLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPF---CTYRENFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFIKAFYVRFLLRLI 4978
            +++F    S IS+A E P K     N I L  A+++F    TIE+ LK+ A G      +  R++  +LD  +  + +I     I+   I      +IL +LR LRPLR       ++ VV  +    R I  + ++  +  F FA  GV +F GK   C D +K  + +C G  +  +   V K   S        PRVW N  +FNFD++   M+ LF V + EGW  +    I +    +  IY +  V     I          + +FVG VI  + E          L  +QR+ ++  LK R     PL  +IP  P   +                           V+ +    YF+ +   ++L+N I L    +   +       IL   N+ +T +F +E  LK+ A    GY+    N++D ++   S+I V +        N+R+ S  F  +  ++R   +  +   ++ L+ T + S     +V + + +L  +YA+ G+ +FG +   +   + R+ NF    +++ LLFR  TGE W +IM  C    P     T   +    +CG+ Q ++IYF SFY++  ++++N+ VA+IM+NF   Y   + +I+  + +  F++ W   D   KG IK   V  LLR I
Sbjct:  728 LILFFILLSSISLAAEDPVKNDSFRNQI-LGYADHVFTGLFTIEIILKMTAYGAFLHKGSFCRNYFNILDLVVVSVSLISSG--IQSSAINV---VKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKFFYCTDSSKQTQAECRGSYIMYKDGDVGKPGRS--------PRVWEN-SDFNFDDVLQGMMALFAVSTFEGWPGLLYRAIDSHSEDVGPIYNYRVVISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKAR-----PLRRYIPKNPYQYK---------------------------VWYVVNSTYFEYLMFTLILLNTICLAMQHHGQTKNFNDAMNIL---NMLFTGLFTVEMILKLIAFKPRGYFSDPWNVFDFLIVIGSIIDVILSEINNSEENARI-SITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMFGKIALRDLSQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACSPNRPCEKGSTNENSTASEECGS-QFAIIYFVSFYMLCAFLIINLFVAVIMDNFD--YLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRI 1335

HSP 2 Score: 124.02 bits (310), Expect = 1.160e-27
Identity = 156/637 (24.49%), Postives = 284/637 (44.58%), Query Frame = 2

Query: 3074 VMIFVTTTSCISMAFETP----TKRVMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGS----GK------QILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKL---------AIC-NDPTKTEKKDCVGVFDRKISVTKLKLSGDSPSFLVPRV-WANPRN--FNFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVG-RINVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVD-------QRRWLDLKGRIK-LTQPLHIPPRPKMRQDSTQNRTDNNAINENSFD---------NRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYD-MVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRENFWQSDCGNFQASL--IYFCSFYIMITYIMLNVLVAIIMENFS 4840
            +++     +C+++A   P         N+  L+  EY+F +  T+E  LKV+A G +F P A +R+   +LDF I ++ +   + ++   T G G+    GK      + L   R LRPLR+   VP ++ V+  +++    +L +++L++  +  +A+ G+ +F GK+           C N   K       G + R  +    +           RV W  P +   NFDN   AMLT+F+ +++EGW ++   ++  +G  +  +Y    V  G    L L +GV+   +S+ +  A    D       Q+   DLKG +  +TQ   I P     ++  +   D+   N   +          NR+ + +C     +Q  Y+  +   +V +N + +    +   ++      I    N     +F  E  LK+ +L    Y+ S  N +D  VV    L  + V   +       V+         LLR F I     +L  L+ ++L S+     +++ +FL +++++L G+ LFG  K+  +  R + F N  +S+  +F+I+TGEDWN +M+D ++                 +F   L  IYF   +I   YI+LNV +AI ++N +
Sbjct:   27 IILMTIFANCVALAVYIPFPEDDSNATNS-NLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLF--SAILEQATKGDGATPIGGKAAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCVHNHTGTCLNAEEKPAPCAPDGAYGRHCTQNGTQC----------RVGWEGPNDGITNFDNFAFAMLTVFQCITMEGWTDVLYWMQDAMGYELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDP-----ENEEEGLDDDKPRNRKCYCIQIRYSRRWNRLFRRKCRAAVKSQVFYW--LVIFLVFLNTLTIASEHHRQPQWLTDVQDIA---NKVLLALFTGEMLLKMYSLGLQAYFVSLFNRFDSFVVCGGILETILVETKIMSPLGISVLR-----CVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGG-KFNFDETRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIM------------AYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLA 622

HSP 3 Score: 100.523 bits (249), Expect = 1.732e-20
Identity = 134/571 (23.47%), Postives = 238/571 (41.68%), Query Frame = 2

Query:  521 RPHAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTR-------VLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWLVKNVFIAILTETF------AEIRVQFQQMWSPKNQTDADSSKIFQTDGQRWKLVPVYESKPHGLAP--------------------KLFQE---IVLKSTAFNVIIMLLVLANAIVAAGLHFNHDE-LTQTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFE-FILCLG--------TTVHCMWYRTQLTYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCS-IQIYEPKFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPNDWAQQLFSTFSG----IYFILINLIFSFAFMSMF 2080
             P+AYLR+ W   D I+V+    S  ++     +  K +       +   F  K   L   R  RPL L         VL S +K  +P      +LH        + + +LF + +YAI+G++ F   ++  CV  +   + +   +   P   C P    G  C  +    ++     ++G    F  F F+  TV+Q  + EGW  ++Y   D +       YF+S++ F ++ V N+ + +L+  F      A+ R  FQ++   K Q + D         Q   + P  E++  GL                      +LF+      +KS  F  +++ LV  N +  A  H    + LT       A  V   LF  E + K++ LG ++Y+    ++F+ F++C G        T +      + L   ++LRIF++ +    L +    +  S + +  L+L     +II S + +QLF       E +   F NFP++ L +F ++T E W  VM   ++ A   P         +F G    IYFI++ +  ++  +++F
Sbjct:   84 HPNAYLRNGWNLLDFIIVVVGLFSAILE-----QATKGDGATPIGGKAAGFDVK--ALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVP------LLH--------IALLVLFVIIIYAIIGLELFMGKMHKTCV-HNHTGTCLNAEEKPAP---CAPDGAYGRHCTQNGTQCRVGWEGPNDG-ITNFDNFAFAMLTVFQCITMEGWTDVLYWMQDAMGYELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKL-REKQQLEEDLKGYLDWITQAEDIDP--ENEEEGLDDDKPRNRKCYCIQIRYSRRWNRLFRRKCRAAVKSQVFYWLVIFLVFLNTLTIASEHHRQPQWLTDVQDI--ANKVLLALFTGEMLLKMYSLGLQAYFVSLFNRFDSFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIM-AYGGP---------SFPGMLVCIYFIILFICGNYILLNVF 613

HSP 4 Score: 70.0922 bits (170), Expect = 2.732e-11
Identity = 83/389 (21.34%), Postives = 160/389 (41.13%), Query Frame = 2

Query: 1088 TVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWL---------VKNVFIAILTETFAEIRVQ-FQQMWSPKNQTDADSSKIFQTDGQRWKLVPVYESKPHGLAPKLFQEIVLKSTAFNVIIMLLVLANAIVAAGLHFNHDELTQTNGFYYA----ELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHCMW---------YRTQLTYFQVLRIFRLMK---ASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYE----PKFDRFSNFPKAFLQIFTLVTEEGWIEVM-----TRAMIDAKKIPNDWA-QQLFSTFSGIYFILINLIFSFAFMSMFQILTQKGWVIVMHDTMDMAKHR 2146
             ++  ++ EGW  ++YRA+D   +  G  Y   ++  + ++         + N+F+  +  TF E   Q ++     KNQ       +     +R+     Y+ K            V+ ST F  ++  L+L N I  A  H       QT  F  A     ++FT LF +E + K+     + Y+    + F+F++ +G+ +  +           R  +T+F++ R+ RL+K       +    +    S + L  + L    L  I + + +Q+F  I + +     + + F  FP+A L +F   T E W E+M      R         N  A ++  S F+ IYF+   ++ +F  +++F  +    +  +  D   +  H 
Sbjct:  930 ALFAVSTFEGWPGLLYRAIDSHSEDVGPIYNYRVVISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNPYQYKVW---------YVVNSTYFEYLMFTLILLNTICLAMQHHG-----QTKNFNDAMNILNMLFTGLFTVEMILKLIAFKPRGYFSDPWNVFDFLIVIGSIIDVILSEINNSEENARISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMFGKIALRDLSQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACSPNRPCEKGSTNENSTASEECGSQFAIIYFVSFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHH 1304

[Close]

BLAST of Voltage-dependent calcium channel vs. Planmine SMEST
Match: SMESG000076415.1 (SMESG000076415.1)

HSP 1 Score: 3364.32 bits (8722), Expect = 0.000e+0
Identity = 1652/1669 (98.98%), Postives = 1652/1669 (98.98%), Query Frame = 2

Query:  152 MHRSERKTSHTRETQPTLPGVEFATDDAGDLTSVNWVYTTWARCAFKIXXXXXXXXXXXNTPETFKEYKWLFYVTYLLDIVVALLFTAEMFTKMKIKGIIRPSPYVIVRHLFFVKVSNNIENKRPHAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWLVKNVFIAILTETFAEIRVQFQQMWSPKNQTDADSSKIFQTDGQRWKLVPVYESKPHGLAPKLFQEIVLKSTAFNVIIMLLVLANAIVAAGLHFNHDELTQTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHCMWYRTQLTYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEPKFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPNDWAQQLFSTFSGIYFILINLIFSF-----------------AFMSMFQILTQKGWVIVMHDTMDMAKHRGLNALVAIYFVFYHLFVTLIVLSLFVAVILDNLELEEDIKKLKQLKLREMSAETQQKLPMRLRIFEKFPNRPQMIKPARLLSDFLIPKIRDSFMRQFAQLPTLEEENESDEMIAAAVSGVGVSSLPRALSIEIKRQIRGLKGNDKLNAIIYLINESNKTRMIEQPIIYPTRSLLSTQHQIRTERRNLRNRMAATTMSINQKPRLNGEIRNMDFETNRKTEEANHFDIKILQQKAEQAEIKRNQQVDDLRENHPYFDKPLFTIGRESQFRQLCRMLVEAQYKPDINSENPEKQTFYKLQKFFGLVTYLDWVMIFVTTTSCISMAFETPTKRVMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTKLKLSGDSPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVGRINVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVDQRRWLDLKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRENFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFIKAFYVRFLLRLIPKDRVGFDFTKKKDQQLFKEMCYEVELLRGGKDKEVSFHDVLT 5107
            MHRSERKTSHTRETQPTLPGVEFATDDAGDLTSVNWVYTTWARCAFKIAALLSLASVSANTPETFKEYKWLFYVTYLLDIVVALLFTAEMFTKMKIKGIIRPSPYVIVRHLFFVKVSNNIENKRPHAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWLVKNVFIAILTETFAEIRVQFQQMWSPKNQTDADSSKIFQTDGQRWKLVPVYESKPHGLAPKLFQEIVLKSTAFNVIIMLLVLANAIVAAGLHFNHDELTQTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHCMWYRTQLTYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEPKFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPNDWAQQLFSTFSGIYFILINLIFSF                 AFMSMFQILTQKGWVIVMHDTMDMAKHRGLNALVAIYFVFYHLFVTLIVLSLFVAVILDNLELEEDIKKLKQLKLREMSAETQQKLPMRLRIFEKFPNRPQMIKPARLLSDFLIPKIRDSFMRQFAQLPTLEEENESDEMIAAAVSGVGVSSLPRALSIEIKRQIRGLKGNDKLNAIIYLINESNKTRMIEQPIIYPTRSLLSTQHQIRTERRNLRNRMAATTMSINQKPRLNGEIRNMDFETNRKTEEANHFDIKILQQKAEQAEIKRNQQVDDLRENHPYFDKPLFTIGRESQFRQLCRMLVEAQYKPDINSENPEKQTFYKLQKFFGLVTYLDWVMIFVTTTSCISMAFETPTKRVMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREILMVSVLLVVFMFTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTKLKLSGDSPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVGRINVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVDQRRWLDLKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRENFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFIKAFYVRFLLRLIPKDRVGFDFTKKKDQQLFKEMCYEVELLRGGKDKEVSFHDVLT
Sbjct:    1 MHRSERKTSHTRETQPTLPGVEFATDDAGDLTSVNWVYTTWARCAFKIAALLSLASVSANTPETFKEYKWLFYVTYLLDIVVALLFTAEMFTKMKIKGIIRPSPYVIVRHLFFVKVSNNIENKRPHAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWLVKNVFIAILTETFAEIRVQFQQMWSPKNQTDADSSKIFQTDGQRWKLVPVYESKPHGLAPKLFQEIVLKSTAFNVIIMLLVLANAIVAAGLHFNHDELTQTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHCMWYRTQLTYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEPKFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPNDWAQQLFSTFSGIYFILINLIFSFVRMLEHVPNTHVTFITTAFMSMFQILTQKGWVIVMHDTMDMAKHRGLNALVAIYFVFYHLFVTLIVLSLFVAVILDNLELEEDIKKLKQLKLREMSAETQQKLPMRLRIFEKFPNRPQMIKPARLLSDFLIPKIRDSFMRQFAQLPTLEEENESDEMIAAAVSGVGVSSLPRALSIEIKRQIRGLKGNDKLNAIIYLINESNKTRMIEQPIIYPTRSLLSTQHQIRTERRNLRNRMAATTMSINQKPRLNGEIRNMDFETNRKTEEANHFDIKILQQKAEQAEIKRNQQVDDLRENHPYFDKPLFTIGRESQFRQLCRMLVEAQYKPDINSENPEKQTFYKLQKFFGLVTYLDWVMIFVTTTSCISMAFETPTKRVMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREILMVSVLLVVFMFTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTKLKLSGDSPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVGRINVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVDQRRWLDLKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRENFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFIKAFYVRFLLRLIPKDRVGFDFTKKKDQQLFKEMCYEVELLRGGKDKEVSFHDVLT 1669

[Close]

BLAST of Voltage-dependent calcium channel vs. Planmine SMEST
Match: SMESG000076415.1 (SMESG000076415.1)

HSP 1 Score: 3339.28 bits (8657), Expect = 0.000e+0
Identity = 1639/1652 (99.21%), Postives = 1639/1652 (99.21%), Query Frame = 2

Query:  152 MHRSERKTSHTRETQPTLPGVEFATDDAGDLTSVNWVYTTWARCAFKIXXXXXXXXXXXNTPETFKEYKWLFYVTYLLDIVVALLFTAEMFTKMKIKGIIRPSPYVIVRHLFFVKVSNNIENKRPHAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWLVKNVFIAILTETFAEIRVQFQQMWSPKNQTDADSSKIFQTDGQRWKLVPVYESKPHGLAPKLFQEIVLKSTAFNVIIMLLVLANAIVAAGLHFNHDELTQTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHCMWYRTQLTYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEPKFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPNDWAQQLFSTFSGIYFILINLIFSFAFMSMFQILTQKGWVIVMHDTMDMAKHRGLNALVAIYFVFYHLFVTLIVLSLFVAVILDNLELEEDIKKLKQLKLREMSAETQQKLPMRLRIFEKFPNRPQMIKPARLLSDFLIPKIRDSFMRQFAQLPTLEEENESDEMIAAAVSGVGVSSLPRALSIEIKRQIRGLKGNDKLNAIIYLINESNKTRMIEQPIIYPTRSLLSTQHQIRTERRNLRNRMAATTMSINQKPRLNGEIRNMDFETNRKTEEANHFDIKILQQKAEQAEIKRNQQVDDLRENHPYFDKPLFTIGRESQFRQLCRMLVEAQYKPDINSENPEKQTFYKLQKFFGLVTYLDWVMIFVTTTSCISMAFETPTKRVMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTKLKLSGDSPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVGRINVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVDQRRWLDLKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRENFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFIKAFYVRFLLRLIPKDRVGFDFTKKKDQQLFKEMCYEVELLRGGKDKEVSFHDVLT 5107
            MHRSERKTSHTRETQPTLPGVEFATDDAGDLTSVNWVYTTWARCAFKIAALLSLASVSANTPETFKEYKWLFYVTYLLDIVVALLFTAEMFTKMKIKGIIRP             VSNNIENKRPHAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWLVKNVFIAILTETFAEIRVQFQQMWSPKNQTDADSSKIFQTDGQRWKLVPVYESKPHGLAPKLFQEIVLKSTAFNVIIMLLVLANAIVAAGLHFNHDELTQTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHCMWYRTQLTYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEPKFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPNDWAQQLFSTFSGIYFILINLIFSFAFMSMFQILTQKGWVIVMHDTMDMAKHRGLNALVAIYFVFYHLFVTLIVLSLFVAVILDNLELEEDIKKLKQLKLREMSAETQQKLPMRLRIFEKFPNRPQMIKPARLLSDFLIPKIRDSFMRQFAQLPTLEEENESDEMIAAAVSGVGVSSLPRALSIEIKRQIRGLKGNDKLNAIIYLINESNKTRMIEQPIIYPTRSLLSTQHQIRTERRNLRNRMAATTMSINQKPRLNGEIRNMDFETNRKTEEANHFDIKILQQKAEQAEIKRNQQVDDLRENHPYFDKPLFTIGRESQFRQLCRMLVEAQYKPDINSENPEKQTFYKLQKFFGLVTYLDWVMIFVTTTSCISMAFETPTKRVMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREILMVSVLLVVFMFTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTKLKLSGDSPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVGRINVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVDQRRWLDLKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRENFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFIKAFYVRFLLRLIPKDRVGFDFTKKKDQQLFKEMCYEVELLRGGKDKEVSFHDVLT
Sbjct:    1 MHRSERKTSHTRETQPTLPGVEFATDDAGDLTSVNWVYTTWARCAFKIAALLSLASVSANTPETFKEYKWLFYVTYLLDIVVALLFTAEMFTKMKIKGIIRP-------------VSNNIENKRPHAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWLVKNVFIAILTETFAEIRVQFQQMWSPKNQTDADSSKIFQTDGQRWKLVPVYESKPHGLAPKLFQEIVLKSTAFNVIIMLLVLANAIVAAGLHFNHDELTQTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHCMWYRTQLTYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEPKFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPNDWAQQLFSTFSGIYFILINLIFSFAFMSMFQILTQKGWVIVMHDTMDMAKHRGLNALVAIYFVFYHLFVTLIVLSLFVAVILDNLELEEDIKKLKQLKLREMSAETQQKLPMRLRIFEKFPNRPQMIKPARLLSDFLIPKIRDSFMRQFAQLPTLEEENESDEMIAAAVSGVGVSSLPRALSIEIKRQIRGLKGNDKLNAIIYLINESNKTRMIEQPIIYPTRSLLSTQHQIRTERRNLRNRMAATTMSINQKPRLNGEIRNMDFETNRKTEEANHFDIKILQQKAEQAEIKRNQQVDDLRENHPYFDKPLFTIGRESQFRQLCRMLVEAQYKPDINSENPEKQTFYKLQKFFGLVTYLDWVMIFVTTTSCISMAFETPTKRVMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREILMVSVLLVVFMFTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTKLKLSGDSPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVGRINVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVDQRRWLDLKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRENFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFIKAFYVRFLLRLIPKDRVGFDFTKKKDQQLFKEMCYEVELLRGGKDKEVSFHDVLT 1639

[Close]

BLAST of Voltage-dependent calcium channel vs. Planmine SMEST
Match: SMESG000076415.1 (SMESG000076415.1)

HSP 1 Score: 3330.04 bits (8633), Expect = 0.000e+0
Identity = 1639/1669 (98.20%), Postives = 1639/1669 (98.20%), Query Frame = 2

Query:  152 MHRSERKTSHTRETQPTLPGVEFATDDAGDLTSVNWVYTTWARCAFKIXXXXXXXXXXXNTPETFKEYKWLFYVTYLLDIVVALLFTAEMFTKMKIKGIIRPSPYVIVRHLFFVKVSNNIENKRPHAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWLVKNVFIAILTETFAEIRVQFQQMWSPKNQTDADSSKIFQTDGQRWKLVPVYESKPHGLAPKLFQEIVLKSTAFNVIIMLLVLANAIVAAGLHFNHDELTQTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHCMWYRTQLTYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEPKFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPNDWAQQLFSTFSGIYFILINLIFSF-----------------AFMSMFQILTQKGWVIVMHDTMDMAKHRGLNALVAIYFVFYHLFVTLIVLSLFVAVILDNLELEEDIKKLKQLKLREMSAETQQKLPMRLRIFEKFPNRPQMIKPARLLSDFLIPKIRDSFMRQFAQLPTLEEENESDEMIAAAVSGVGVSSLPRALSIEIKRQIRGLKGNDKLNAIIYLINESNKTRMIEQPIIYPTRSLLSTQHQIRTERRNLRNRMAATTMSINQKPRLNGEIRNMDFETNRKTEEANHFDIKILQQKAEQAEIKRNQQVDDLRENHPYFDKPLFTIGRESQFRQLCRMLVEAQYKPDINSENPEKQTFYKLQKFFGLVTYLDWVMIFVTTTSCISMAFETPTKRVMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTKLKLSGDSPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVGRINVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVDQRRWLDLKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRENFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFIKAFYVRFLLRLIPKDRVGFDFTKKKDQQLFKEMCYEVELLRGGKDKEVSFHDVLT 5107
            MHRSERKTSHTRETQPTLPGVEFATDDAGDLTSVNWVYTTWARCAFKIAALLSLASVSANTPETFKEYKWLFYVTYLLDIVVALLFTAEMFTKMKIKGIIRP             VSNNIENKRPHAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWLVKNVFIAILTETFAEIRVQFQQMWSPKNQTDADSSKIFQTDGQRWKLVPVYESKPHGLAPKLFQEIVLKSTAFNVIIMLLVLANAIVAAGLHFNHDELTQTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHCMWYRTQLTYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEPKFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPNDWAQQLFSTFSGIYFILINLIFSF                 AFMSMFQILTQKGWVIVMHDTMDMAKHRGLNALVAIYFVFYHLFVTLIVLSLFVAVILDNLELEEDIKKLKQLKLREMSAETQQKLPMRLRIFEKFPNRPQMIKPARLLSDFLIPKIRDSFMRQFAQLPTLEEENESDEMIAAAVSGVGVSSLPRALSIEIKRQIRGLKGNDKLNAIIYLINESNKTRMIEQPIIYPTRSLLSTQHQIRTERRNLRNRMAATTMSINQKPRLNGEIRNMDFETNRKTEEANHFDIKILQQKAEQAEIKRNQQVDDLRENHPYFDKPLFTIGRESQFRQLCRMLVEAQYKPDINSENPEKQTFYKLQKFFGLVTYLDWVMIFVTTTSCISMAFETPTKRVMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREILMVSVLLVVFMFTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTKLKLSGDSPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVGRINVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVDQRRWLDLKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRENFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFIKAFYVRFLLRLIPKDRVGFDFTKKKDQQLFKEMCYEVELLRGGKDKEVSFHDVLT
Sbjct:    1 MHRSERKTSHTRETQPTLPGVEFATDDAGDLTSVNWVYTTWARCAFKIAALLSLASVSANTPETFKEYKWLFYVTYLLDIVVALLFTAEMFTKMKIKGIIRP-------------VSNNIENKRPHAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWLVKNVFIAILTETFAEIRVQFQQMWSPKNQTDADSSKIFQTDGQRWKLVPVYESKPHGLAPKLFQEIVLKSTAFNVIIMLLVLANAIVAAGLHFNHDELTQTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHCMWYRTQLTYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEPKFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPNDWAQQLFSTFSGIYFILINLIFSFVRMLEHVPNTHVTFITTAFMSMFQILTQKGWVIVMHDTMDMAKHRGLNALVAIYFVFYHLFVTLIVLSLFVAVILDNLELEEDIKKLKQLKLREMSAETQQKLPMRLRIFEKFPNRPQMIKPARLLSDFLIPKIRDSFMRQFAQLPTLEEENESDEMIAAAVSGVGVSSLPRALSIEIKRQIRGLKGNDKLNAIIYLINESNKTRMIEQPIIYPTRSLLSTQHQIRTERRNLRNRMAATTMSINQKPRLNGEIRNMDFETNRKTEEANHFDIKILQQKAEQAEIKRNQQVDDLRENHPYFDKPLFTIGRESQFRQLCRMLVEAQYKPDINSENPEKQTFYKLQKFFGLVTYLDWVMIFVTTTSCISMAFETPTKRVMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREILMVSVLLVVFMFTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTKLKLSGDSPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVGRINVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVDQRRWLDLKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRENFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFIKAFYVRFLLRLIPKDRVGFDFTKKKDQQLFKEMCYEVELLRGGKDKEVSFHDVLT 1656

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BLAST of Voltage-dependent calcium channel vs. Planmine SMEST
Match: SMESG000076415.1 (SMESG000076415.1)

HSP 1 Score: 3229.11 bits (8371), Expect = 0.000e+0
Identity = 1595/1652 (96.55%), Postives = 1595/1652 (96.55%), Query Frame = 2

Query:  152 MHRSERKTSHTRETQPTLPGVEFATDDAGDLTSVNWVYTTWARCAFKIXXXXXXXXXXXNTPETFKEYKWLFYVTYLLDIVVALLFTAEMFTKMKIKGIIRPSPYVIVRHLFFVKVSNNIENKRPHAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWLVKNVFIAILTETFAEIRVQFQQMWSPKNQTDADSSKIFQTDGQRWKLVPVYESKPHGLAPKLFQEIVLKSTAFNVIIMLLVLANAIVAAGLHFNHDELTQTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHCMWYRTQLTYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEPKFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPNDWAQQLFSTFSGIYFILINLIFSFAFMSMFQILTQKGWVIVMHDTMDMAKHRGLNALVAIYFVFYHLFVTLIVLSLFVAVILDNLELEEDIKKLKQLKLREMSAETQQKLPMRLRIFEKFPNRPQMIKPARLLSDFLIPKIRDSFMRQFAQLPTLEEENESDEMIAAAVSGVGVSSLPRALSIEIKRQIRGLKGNDKLNAIIYLINESNKTRMIEQPIIYPTRSLLSTQHQIRTERRNLRNRMAATTMSINQKPRLNGEIRNMDFETNRKTEEANHFDIKILQQKAEQAEIKRNQQVDDLRENHPYFDKPLFTIGRESQFRQLCRMLVEAQYKPDINSENPEKQTFYKLQKFFGLVTYLDWVMIFVTTTSCISMAFETPTKRVMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTKLKLSGDSPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVGRINVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVDQRRWLDLKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRENFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFIKAFYVRFLLRLIPKDRVGFDFTKKKDQQLFKEMCYEVELLRGGKDKEVSFHDVLT 5107
            MHRSERKTSHTRETQPTLPGVEFATDDAGDLTSVNWVYTTWARCAFKIAALLSLASVSANTPETFKEYKWLFYVTYLLDIVVALLFTAEMFTKMKIKGIIRPSPYVIVRHLFFVKVSNNIENKRPHAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWLVKNVFIAILTETFAEIRVQFQQMWSPKNQTDADSSKIFQTDGQRWKLVPVYESKPHGLAPKLFQEIVLKSTAFNVIIMLLVLANAIVAAGLHFNHDELTQTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHCMWYRTQLTYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEPKFDR                                          FS F              AFMSMFQILTQKGWVIVMHDTMDMAKHRGLNALVAIYFVFYHLFVTLIVLSLFVAVILDNLELEEDIKKLKQLKLREMSAETQQKLPMRLRIFEKFPNRPQMIKPARLLSDFLIPKIRDSFMRQFAQLPTLEEENESDEMIAAAVSGVGVSSLPRALSIEIKRQIRGLKGNDKLNAIIYLINESNKTRMIEQPIIYPTRSLLSTQHQIRTERRNLRNRMAATTMSINQKPRLNGEIRNMDFETNRKTEEANHFDIKILQQKAEQAEIKRNQQVDDLRENHPYFDKPLFTIGRESQFRQLCRMLVEAQYKPDINSENPEKQTFYKLQKFFGLVTYLDWVMIFVTTTSCISMAFETPTKRVMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREILMVSVLLVVFMFTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTKLKLSGDSPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVGRINVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVDQRRWLDLKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRENFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFIKAFYVRFLLRLIPKDRVGFDFTKKKDQQLFKEMCYEVELLRGGKDKEVSFHDVLT
Sbjct:    1 MHRSERKTSHTRETQPTLPGVEFATDDAGDLTSVNWVYTTWARCAFKIAALLSLASVSANTPETFKEYKWLFYVTYLLDIVVALLFTAEMFTKMKIKGIIRPSPYVIVRHLFFVKVSNNIENKRPHAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWLVKNVFIAILTETFAEIRVQFQQMWSPKNQTDADSSKIFQTDGQRWKLVPVYESKPHGLAPKLFQEIVLKSTAFNVIIMLLVLANAIVAAGLHFNHDELTQTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHCMWYRTQLTYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEPKFDR------------------------------------------FSNFPK------------AFMSMFQILTQKGWVIVMHDTMDMAKHRGLNALVAIYFVFYHLFVTLIVLSLFVAVILDNLELEEDIKKLKQLKLREMSAETQQKLPMRLRIFEKFPNRPQMIKPARLLSDFLIPKIRDSFMRQFAQLPTLEEENESDEMIAAAVSGVGVSSLPRALSIEIKRQIRGLKGNDKLNAIIYLINESNKTRMIEQPIIYPTRSLLSTQHQIRTERRNLRNRMAATTMSINQKPRLNGEIRNMDFETNRKTEEANHFDIKILQQKAEQAEIKRNQQVDDLRENHPYFDKPLFTIGRESQFRQLCRMLVEAQYKPDINSENPEKQTFYKLQKFFGLVTYLDWVMIFVTTTSCISMAFETPTKRVMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREILMVSVLLVVFMFTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTKLKLSGDSPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVGRINVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVDQRRWLDLKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRENFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFIKAFYVRFLLRLIPKDRVGFDFTKKKDQQLFKEMCYEVELLRGGKDKEVSFHDVLT 1598

[Close]

BLAST of Voltage-dependent calcium channel vs. Planmine SMEST
Match: SMESG000076415.1 (SMESG000076415.1)

HSP 1 Score: 3192.52 bits (8276), Expect = 0.000e+0
Identity = 1582/1652 (95.76%), Postives = 1582/1652 (95.76%), Query Frame = 2

Query:  152 MHRSERKTSHTRETQPTLPGVEFATDDAGDLTSVNWVYTTWARCAFKIXXXXXXXXXXXNTPETFKEYKWLFYVTYLLDIVVALLFTAEMFTKMKIKGIIRPSPYVIVRHLFFVKVSNNIENKRPHAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWLVKNVFIAILTETFAEIRVQFQQMWSPKNQTDADSSKIFQTDGQRWKLVPVYESKPHGLAPKLFQEIVLKSTAFNVIIMLLVLANAIVAAGLHFNHDELTQTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHCMWYRTQLTYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEPKFDRFSNFPKAFLQIFTLVTEEGWIEVMTRAMIDAKKIPNDWAQQLFSTFSGIYFILINLIFSFAFMSMFQILTQKGWVIVMHDTMDMAKHRGLNALVAIYFVFYHLFVTLIVLSLFVAVILDNLELEEDIKKLKQLKLREMSAETQQKLPMRLRIFEKFPNRPQMIKPARLLSDFLIPKIRDSFMRQFAQLPTLEEENESDEMIAAAVSGVGVSSLPRALSIEIKRQIRGLKGNDKLNAIIYLINESNKTRMIEQPIIYPTRSLLSTQHQIRTERRNLRNRMAATTMSINQKPRLNGEIRNMDFETNRKTEEANHFDIKILQQKAEQAEIKRNQQVDDLRENHPYFDKPLFTIGRESQFRQLCRMLVEAQYKPDINSENPEKQTFYKLQKFFGLVTYLDWVMIFVTTTSCISMAFETPTKRVMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREIXXXXXXXXXXXXTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTKLKLSGDSPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVGRINVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVDQRRWLDLKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRENFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFIKAFYVRFLLRLIPKDRVGFDFTKKKDQQLFKEMCYEVELLRGGKDKEVSFHDVLT 5107
            MHRSERKTSHTRETQPTLPGVEFATDDAGDLTSVNWVYTTWARCAFKIAALLSLASVSANTPETFKEYKWLFYVTYLLDIVVALLFTAEMFTKMKIKGIIRP             VSNNIENKRPHAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWLVKNVFIAILTETFAEIRVQFQQMWSPKNQTDADSSKIFQTDGQRWKLVPVYESKPHGLAPKLFQEIVLKSTAFNVIIMLLVLANAIVAAGLHFNHDELTQTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHCMWYRTQLTYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEPKFDR                                          FS F              AFMSMFQILTQKGWVIVMHDTMDMAKHRGLNALVAIYFVFYHLFVTLIVLSLFVAVILDNLELEEDIKKLKQLKLREMSAETQQKLPMRLRIFEKFPNRPQMIKPARLLSDFLIPKIRDSFMRQFAQLPTLEEENESDEMIAAAVSGVGVSSLPRALSIEIKRQIRGLKGNDKLNAIIYLINESNKTRMIEQPIIYPTRSLLSTQHQIRTERRNLRNRMAATTMSINQKPRLNGEIRNMDFETNRKTEEANHFDIKILQQKAEQAEIKRNQQVDDLRENHPYFDKPLFTIGRESQFRQLCRMLVEAQYKPDINSENPEKQTFYKLQKFFGLVTYLDWVMIFVTTTSCISMAFETPTKRVMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREILMVSVLLVVFMFTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTKLKLSGDSPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVGRINVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVDQRRWLDLKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRENFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFIKAFYVRFLLRLIPKDRVGFDFTKKKDQQLFKEMCYEVELLRGGKDKEVSFHDVLT
Sbjct:    1 MHRSERKTSHTRETQPTLPGVEFATDDAGDLTSVNWVYTTWARCAFKIAALLSLASVSANTPETFKEYKWLFYVTYLLDIVVALLFTAEMFTKMKIKGIIRP-------------VSNNIENKRPHAYLRHFWGCFDTIMVICLWISITIQTFELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFLKFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHCVLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANSIEDEGGYAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFLAWLVKNVFIAILTETFAEIRVQFQQMWSPKNQTDADSSKIFQTDGQRWKLVPVYESKPHGLAPKLFQEIVLKSTAFNVIIMLLVLANAIVAAGLHFNHDELTQTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGTTVHCMWYRTQLTYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFTSCLLIITSSVSLQLFCSIQIYEPKFDR------------------------------------------FSNFPK------------AFMSMFQILTQKGWVIVMHDTMDMAKHRGLNALVAIYFVFYHLFVTLIVLSLFVAVILDNLELEEDIKKLKQLKLREMSAETQQKLPMRLRIFEKFPNRPQMIKPARLLSDFLIPKIRDSFMRQFAQLPTLEEENESDEMIAAAVSGVGVSSLPRALSIEIKRQIRGLKGNDKLNAIIYLINESNKTRMIEQPIIYPTRSLLSTQHQIRTERRNLRNRMAATTMSINQKPRLNGEIRNMDFETNRKTEEANHFDIKILQQKAEQAEIKRNQQVDDLRENHPYFDKPLFTIGRESQFRQLCRMLVEAQYKPDINSENPEKQTFYKLQKFFGLVTYLDWVMIFVTTTSCISMAFETPTKRVMNTIELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICIIFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGFREILMVSVLLVVFMFTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRKISVTKLKLSGDSPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVEIRDVIKARVGRINVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLTVDQRRWLDLKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAINENSFDNRVIKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILASFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHISVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLFVIIAMFLLMLVYALAGIILFGSVKYGENLGRHANFHNTFRSIALLFRIVTGEDWNKIMHDCMVQPPFCTYRENFWQSDCGNFQASLIYFCSFYIMITYIMLNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFIKAFYVRFLLRLIPKDRVGFDFTKKKDQQLFKEMCYEVELLRGGKDKEVSFHDVLT 1585

The following BLAST results are available for this feature:

BLAST of Voltage-dependent calcium channel vs. Ensembl Human
BLAST of Voltage-dependent calcium channel vs. Ensembl Celegans
BLAST of Voltage-dependent calcium channel vs. Ensembl Fly
BLAST of Voltage-dependent calcium channel vs. Ensembl Zebrafish
BLAST of Voltage-dependent calcium channel vs. Ensembl Xenopus
BLAST of Voltage-dependent calcium channel vs. Ensembl Mouse
BLAST of Voltage-dependent calcium channel vs. UniProt/SwissProt
BLAST of Voltage-dependent calcium channel vs. TrEMBL
BLAST of Voltage-dependent calcium channel vs. Ensembl Cavefish
BLAST of Voltage-dependent calcium channel vs. Ensembl Sea Lamprey
BLAST of Voltage-dependent calcium channel vs. Ensembl Yeast
BLAST of Voltage-dependent calcium channel vs. Ensembl Nematostella
BLAST of Voltage-dependent calcium channel vs. Ensembl Medaka
BLAST of Voltage-dependent calcium channel vs. Planmine SMEST

BLAST of Voltage-dependent calcium channel vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
NALCN	0.000e+0	44.74	sodium leak channel, non-selective [Source:HGNC Sy...	[more]
NALCN	0.000e+0	46.90	sodium leak channel, non-selective [Source:HGNC Sy...	[more]
CACNA1C	2.958e-43	26.22	calcium voltage-gated channel subunit alpha1 C [So...	[more]
CACNA1C	2.958e-43	26.22	calcium voltage-gated channel subunit alpha1 C [So...	[more]
CACNA1C	1.507e-42	26.22	calcium voltage-gated channel subunit alpha1 C [So...	[more]

BLAST of Voltage-dependent calcium channel vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
nca-2	0.000e+0	44.19	Four domain-type voltage-gated ion channel alpha-1...	[more]
nca-2	0.000e+0	43.72	Four domain-type voltage-gated ion channel alpha-1...	[more]
unc-77	0.000e+0	43.02	pep chromosome:WBcel235:IV:6157312:6173040:-1 gene...	[more]
unc-77	0.000e+0	42.96	pep chromosome:WBcel235:IV:6157312:6173040:-1 gene...	[more]
unc-77	0.000e+0	43.07	pep chromosome:WBcel235:IV:6157312:6183857:-1 gene...	[more]

BLAST of Voltage-dependent calcium channel vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
na	0.000e+0	48.37	gene:FBgn0002917 transcript:FBtr0344823	[more]
na	0.000e+0	48.18	gene:FBgn0002917 transcript:FBtr0344822	[more]
cac	6.020e-50	27.68	gene:FBgn0263111 transcript:FBtr0332391	[more]
cac	6.326e-50	27.48	gene:FBgn0263111 transcript:FBtr0307315	[more]
cac	7.620e-50	27.48	gene:FBgn0263111 transcript:FBtr0307316	[more]

BLAST of Voltage-dependent calcium channel vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
nalcn	0.000e+0	47.62	sodium leak channel, non-selective [Source:ZFIN;Ac...	[more]
nalcn	0.000e+0	47.62	sodium leak channel, non-selective [Source:ZFIN;Ac...	[more]
nalcn	6.750e-87	42.00	sodium leak channel, non-selective [Source:ZFIN;Ac...	[more]
nalcn	1.476e-86	42.00	sodium leak channel, non-selective [Source:ZFIN;Ac...	[more]
cacna1bb	3.466e-45	25.03	calcium channel, voltage-dependent, N type, alpha ...	[more]

BLAST of Voltage-dependent calcium channel vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
NALCN	0.000e+0	44.74	sodium leak channel, non selective [Source:NCBI ge...	[more]
NALCN	0.000e+0	44.47	sodium leak channel, non selective [Source:NCBI ge...	[more]
NALCN	0.000e+0	44.22	sodium leak channel, non selective [Source:NCBI ge...	[more]
mrps11	5.855e-51	22.99	mitochondrial ribosomal protein S11 [Source:Xenbas...	[more]
mrps11	1.191e-50	22.94	mitochondrial ribosomal protein S11 [Source:Xenbas...	[more]

BLAST of Voltage-dependent calcium channel vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Nalcn	0.000e+0	45.29	sodium leak channel, non-selective [Source:MGI Sym...	[more]
Cacna1s	3.625e-46	24.94	calcium channel, voltage-dependent, L type, alpha ...	[more]
Cacna1s	5.491e-46	24.91	calcium channel, voltage-dependent, L type, alpha ...	[more]
Cacna1c	2.293e-44	26.50	calcium channel, voltage-dependent, L type, alpha ...	[more]
Cacna1c	1.214e-43	26.22	calcium channel, voltage-dependent, L type, alpha ...	[more]

BLAST of Voltage-dependent calcium channel vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q8BXR5\|NALCN_MOUSE	0.000e+0	45.29	Sodium leak channel non-selective protein OS=Mus m...	[more]
sp\|Q6Q760\|NALCN_RAT	0.000e+0	45.00	Sodium leak channel non-selective protein OS=Rattu...	[more]
sp\|Q8IZF0\|NALCN_HUMAN	0.000e+0	44.74	Sodium leak channel non-selective protein OS=Homo ...	[more]
sp\|O14234\|CCH1_SCHPO	9.213e-63	26.47	Calcium-channel protein cch1 OS=Schizosaccharomyce...	[more]
sp\|P50077\|CCH1_YEAST	2.320e-49	25.14	Calcium-channel protein CCH1 OS=Saccharomyces cere...	[more]

BLAST of Voltage-dependent calcium channel vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A4Z2CZB1	0.000e+0	61.56	Sodium leak channel non-selective protein isoform ...	[more]
A0A4S2LXR2	0.000e+0	59.80	Uncharacterized protein OS=Opisthorchis felineus O...	[more]
A0A4Z2CZ74	0.000e+0	61.09	Sodium leak channel non-selective protein isoform ...	[more]
A0A4S2LXR3	0.000e+0	59.85	Uncharacterized protein OS=Opisthorchis felineus O...	[more]
G4VG52	0.000e+0	61.25	Voltage-dependent calcium channel OS=Schistosoma m...	[more]

BLAST of Voltage-dependent calcium channel vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
nalcn	0.000e+0	45.54	sodium leak channel, non-selective [Source:ZFIN;Ac...	[more]
cacna1ba	1.042e-44	27.08	calcium channel, voltage-dependent, N type, alpha ...	[more]
cacna1da	8.820e-44	25.71	calcium channel, voltage-dependent, L type, alpha ...	[more]
cacna1da	3.106e-43	25.71	calcium channel, voltage-dependent, L type, alpha ...	[more]
cacna1sb	1.979e-42	25.23	calcium channel, voltage-dependent, L type, alpha ...	[more]

BLAST of Voltage-dependent calcium channel vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSPMAT00000008004.1	1.384e-30	25.50	pep scaffold:Pmarinus_7.0:GL477228:88466:118438:1 ...	[more]
ENSPMAT00000002303.1	1.211e-21	23.80	pep scaffold:Pmarinus_7.0:GL476946:177796:226078:1...	[more]
ENSPMAT00000002291.1	1.739e-21	23.80	pep scaffold:Pmarinus_7.0:GL476946:177790:226078:1...	[more]
ENSPMAT00000005302.1	6.191e-19	28.38	pep scaffold:Pmarinus_7.0:GL483978:134:5921:-1 gen...	[more]
ENSPMAT00000010500.1	6.348e-19	32.50	pep scaffold:Pmarinus_7.0:GL477503:21958:35427:1 g...	[more]

BLAST of Voltage-dependent calcium channel vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1


Match Name	E-value	Identity	Description
CCH1	3.342e-51	25.14	Voltage-gated high-affinity calcium channel; invol...	[more]

BLAST of Voltage-dependent calcium channel vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO45175	0.000e+0	39.30	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO45174	0.000e+0	38.78	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO35661	1.420e-41	28.12	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO46991	1.928e-38	24.53	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO46797	8.656e-35	24.41	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Voltage-dependent calcium channel vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
nalcn	0.000e+0	45.46	sodium leak channel, non-selective [Source:NCBI ge...	[more]
nalcn	0.000e+0	45.46	sodium leak channel, non-selective [Source:NCBI ge...	[more]
nalcn	0.000e+0	44.96	sodium leak channel, non-selective [Source:NCBI ge...	[more]
cacna1c	9.608e-43	26.20	voltage-dependent L-type calcium channel subunit a...	[more]
cacna1c	1.470e-42	26.74	voltage-dependent L-type calcium channel subunit a...	[more]

BLAST of Voltage-dependent calcium channel vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000076415.1	0.000e+0	98.98	SMESG000076415.1	[more]
SMESG000076415.1	0.000e+0	99.21	SMESG000076415.1	[more]
SMESG000076415.1	0.000e+0	98.20	SMESG000076415.1	[more]
SMESG000076415.1	0.000e+0	96.55	SMESG000076415.1	[more]
SMESG000076415.1	0.000e+0	95.76	SMESG000076415.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30019733 ID=SMED30019733|Name=Voltage-dependent calcium channel|organism=Schmidtea mediterranea sexual|type=transcript|length=6014bp
TTTTTGAATTATAATTTACAATAAATTATTATCAATAAAGTTATATTTTT
CTAACCTGTAACTATTTTGGCAGTTCACTATTTTGTTAAAAGTGCTTAAT
TTATTTTGAATAATAAAAATTAATGATTAAATAACAATCATTCCGATTAC
TATGCATCGAAGTGAACGAAAAACTAGTCATACAAGAGAGACTCAACCAA
CTTTACCAGGTGTAGAATTTGCCACCGACGATGCGGGTGATTTGACATCA
GTTAACTGGGTCTATACGACATGGGCAAGATGTGCATTTAAAATTGCCGC
ATTGTTAAGTCTAGCTTCAGTCAGTGCCAATACACCAGAGACATTTAAAG
AATACAAGTGGTTATTCTATGTCACTTATCTACTTGACATCGTTGTGGCG
CTGTTATTCACAGCAGAAATGTTTACCAAAATGAAAATAAAGGGCATCAT
TCGCCCGTCACCGTATGTGATTGTTCGCCATTTATTCTTTGTAAAGGTAT
CAAATAATATTGAAAACAAACGGCCTCATGCTTATCTAAGACATTTTTGG
GGTTGTTTTGACACAATAATGGTGATTTGCTTGTGGATTAGTATAACTAT
CCAAACGTTTGAGCTGTTAAAAGTCATCAAATGTGAAACTCCTTTGGATT
CTTGCAAAGAGTTGATAACGTTTTGGCAGAAATACGGTCTCCTATCCACC
CTTCGAAGTCCAAGACCTTTGATTCTTACCAGAGTATTGAGATCATTCTT
AAAATTCAGACTACCTCAAACTCGAGTGAAAGCTATTTTACACCGTTCAA
CGCATCAAGTATACAATGTCACGGTATTTCTGCTGTTCTTCATGTCTCTC
TACGCCATCCTTGGGGTCCAGTTTTTTGGAGACGACATCAATCATCATTG
CGTTCTGCAGAGTGCTAATGAATCAGATATCAAAATTACAGATCTGGCCA
TTCCGGATTCTTTCTGCAATCCAAAATTTAAATCCGGCGATTCTTGTCCA
TATTCAATGAAATGCGTTAAAATTGCAAATTCTATTGAAGACGAAGGGGG
TTACGCGGGATTCGGCACTTTCCATTTTAGCTTTTTTACGGTCTACCAAG
CAGCTTCCCAGGAAGGATGGGTATTCATCATGTACCGAGCGATGGATTGC
CTTCCACAGTGGAAAGGAGTTTCTTACTTTATATCAATGATATTCTTTTT
AGCATGGCTTGTCAAAAACGTTTTCATTGCCATTCTGACTGAAACCTTTG
CTGAGATCAGAGTTCAATTTCAACAAATGTGGTCACCAAAAAATCAGACC
GATGCAGACAGTTCTAAAATATTCCAAACGGATGGTCAAAGGTGGAAACT
GGTCCCAGTCTACGAAAGCAAGCCACACGGGCTAGCTCCAAAATTATTCC
AAGAAATCGTCCTGAAATCGACGGCATTCAACGTTATCATAATGCTGTTG
GTCCTTGCCAATGCCATTGTCGCAGCTGGGCTGCATTTTAATCACGACGA
GTTAACTCAAACAAATGGTTTCTACTATGCAGAGTTGGTATTCACAATTT
TATTCAACATCGAAGCTGTATTCAAGATCTGGTGCCTCGGATGGAAAAGT
TATTGGTATAGAAGCTTGCATAAATTCGAGTTCATCCTTTGCCTGGGGAC
AACAGTCCATTGCATGTGGTACAGAACACAACTCACATATTTCCAGGTAT
TGAGAATATTCCGGTTGATGAAGGCTTCTCCGATGCTGGAGGATTTCTGT
TTCAAAATATTCGGCTCAGGGAAAAAATTGGGAATTCTCATCCTATTTAC
CAGCTGCTTGTTGATCATCACTTCCAGTGTCAGCCTCCAACTCTTCTGTT
CCATACAGATCTACGAGCCGAAGTTCGACAGGTTTTCCAATTTTCCAAAG
GCGTTTCTCCAGATATTTACTTTGGTGACCGAGGAAGGCTGGATTGAGGT
TATGACAAGAGCAATGATTGACGCGAAGAAAATCCCCAATGATTGGGCTC
AGCAATTGTTTTCCACCTTTTCCGGAATTTACTTCATCCTGATCAACTTA
ATATTTTCCTTTGCGTTTATGTCGATGTTCCAAATCCTGACCCAGAAAGG
ATGGGTGATTGTAATGCATGATACAATGGATATGGCTAAACATCGCGGTT
TGAATGCTTTAGTTGCAATCTATTTTGTATTTTACCACCTTTTCGTTACA
TTGATAGTGCTGAGCTTGTTTGTTGCTGTCATTCTTGACAATCTTGAATT
GGAGGAAGATATTAAAAAGTTAAAACAATTAAAGTTGCGAGAAATGAGTG
CAGAAACCCAGCAGAAATTGCCCATGAGGTTGCGAATATTTGAGAAGTTC
CCAAACCGGCCGCAAATGATAAAACCTGCTCGACTCCTCTCTGATTTCCT
AATTCCTAAAATCAGAGACAGCTTCATGAGGCAATTCGCCCAGCTGCCTA
CTCTTGAAGAAGAAAACGAAAGCGATGAAATGATTGCAGCTGCTGTTTCC
GGCGTGGGGGTGTCCAGCTTGCCCCGGGCGCTGAGCATTGAAATCAAAAG
ACAAATAAGAGGATTAAAAGGAAATGATAAGCTTAATGCCATAATTTATT
TAATCAACGAATCCAATAAAACAAGAATGATTGAGCAGCCGATTATTTAC
CCAACACGATCTTTGCTTTCTACGCAGCATCAAATTCGGACAGAGAGACG
GAACCTAAGGAACAGGATGGCAGCAACCACCATGTCTATAAATCAGAAGC
CGCGACTTAATGGGGAAATTAGGAACATGGATTTTGAAACTAACAGAAAA
ACTGAAGAAGCTAATCATTTTGATATAAAGATCCTTCAACAAAAAGCTGA
GCAGGCTGAAATCAAAAGAAACCAACAAGTAGACGACCTCCGGGAAAATC
ATCCTTATTTCGACAAGCCATTGTTCACCATAGGCCGAGAGAGCCAGTTC
CGGCAATTATGTCGAATGTTAGTGGAAGCTCAGTACAAGCCAGATATAAA
TTCCGAAAATCCGGAAAAACAAACATTTTATAAATTACAAAAGTTTTTTG
GTTTAGTAACATATTTGGATTGGGTAATGATCTTTGTGACAACAACATCT
TGCATTTCCATGGCGTTTGAAACCCCGACTAAACGCGTTATGAATACGAT
CGAACTTAAGGTTGCGGAATACATATTTTTTGTTGCAATGACTATTGAAA
TGGCTCTGAAGGTGCTGGCAAACGGTTTCATTTTTACCCCGAAAGCGGTT
GTCAGAGATTTTGGAGGAGTCCTGGATTTCTTCATCTATATTATCTGCAT
TATTTTCGTGGCCTACATGATACGGGTTGACACCATTGGATCGGGATCTG
GGAAACAAATCTTGATGATATTAAGATGCTTGAGACCATTACGTATATTT
TGCCTTGTCCCTCATATGAGGCGGGTTGTCTTTGAGTTGGTAAGAGGATT
TAGGGAAATACTCATGGTCTCGGTCTTGCTTGTGGTCTTTATGTTCACTT
TTGCGGTTTACGGCGTCCACATTTTTGGAGGCAAGCTTGCCATATGTAAT
GATCCAACCAAGACAGAAAAGAAAGATTGTGTTGGAGTTTTTGATCGAAA
AATTTCAGTTACAAAATTAAAATTAAGTGGAGATTCTCCATCGTTTCTCG
TTCCCAGAGTTTGGGCGAATCCCCGAAATTTCAATTTCGACAACATCGGA
AACGCAATGTTGACATTGTTCGAAGTTTTGTCCTTGGAAGGTTGGGTAGA
AATACGAGATGTCATAAAAGCTCGCGTAGGACGAATTAACGTGATATATA
TCCATTTATTTGTCTTTATCGGATGTCTAATTGGGCTCACTTTGTTTGTT
GGCGTTGTCATTGCAAATTACAGTGAAAATAAGGGTACCGCATTACTTAC
TGTAGATCAACGGCGATGGCTCGATTTGAAGGGCCGAATCAAATTGACAC
AGCCGTTGCATATTCCTCCGAGACCAAAAATGCGCCAGGATTCGACCCAA
AACCGCACTGACAACAACGCCATTAATGAGAACTCATTCGACAATCGAGT
TATTAAAGTGCGATGCTGGGTCTACGATTTGACGCAACACATTTATTTCA
AACGTGTAAGCGCAATAATGGTTCTCATTAATTGCATATTTCTATATTTC
CCATGGAATAATGACGATGAATATGGCATGAAGCGCAGCAAAATTCTAGC
CTCCTTCAATGTGACGTGGACATTCATATTTTGTATCGAATGTGCATTGA
AAATAACAGCTCTTTCATTTATTGGATATTGGCAGTCCAAAAGAAACATA
TACGATATGGTCGTCACATTTTTAAGTTTAATTTGGGTCTTCGTTCATAT
AAGTGTTCAAGACAACCATAATTCCCGCGTAATGAGCAACAATTTTGGAT
GGATGACCGTTCTTTTACGATTTTTCTCCATAGCGGGAAAACATGTAACT
CTGAAGATGTTGATGCAAACAGTTCTCATGTCTATGTTTAAGTCCCTTTT
TGTCATAATAGCCATGTTTCTTCTTATGCTCGTTTATGCGTTAGCAGGCA
TCATTTTGTTTGGCAGTGTCAAATATGGAGAAAATTTAGGGAGACATGCA
AATTTCCACAACACCTTCCGTTCAATAGCCTTACTTTTCCGAATAGTGAC
AGGAGAGGATTGGAATAAAATCATGCATGATTGCATGGTTCAGCCACCAT
TTTGTACTTACCGGGAAAATTTCTGGCAGTCAGATTGTGGGAATTTCCAA
GCATCTTTGATATACTTCTGCTCCTTTTACATAATGATAACTTATATTAT
GTTGAATGTCTTAGTCGCTATTATAATGGAAAACTTTTCCTTATTTTATT
CGAACGACGAAGATGCGATCATTAGCTATAATGATATCAGAAACTTCCAG
CAAGCTTGGAATTCAATTGACGTCAACAGAAAAGGATTCATAAAAGCCTT
TTACGTTCGGTTCTTGTTGCGATTAATTCCAAAGGATCGGGTAGGGTTTG
ACTTCACTAAGAAAAAAGATCAGCAGTTATTCAAAGAAATGTGCTATGAG
GTGGAGCTTTTGAGAGGAGGTAAAGATAAAGAAGTCAGTTTCCATGACGT
GTTAACAATGCTTGCATATCGATCTGTCGATATTTCTAAAACTCTTCAGC
TCGAAGAACTGCTGGCCCGCGAAGAATTGGAATATGCCATTGAAGAGGAA
GTCGCTCGTCAAACGATCGCTACTTGGATTGAAAGATGTATTTTTAGAAA
TCGCCAGAAGCATGGTGATCTCAAATTTGGACTTCGAGAGAGCAATGAAA
TGGTGATTCCAATCTTTGATGATAAAAAAGAGGGCCTAGGATTAGATCGA
TCAAGAAAGATAAGCAGTGGAGCTTATCAAACTAAATTTCTATCTCTTCC
AACCCTTGACGGCAGACAAAATACTAGCGATGGCAGTTTACCGTCAAGTG
GGATCACTATTGGTCGATTAAATGATCATTTAAAAAATCAGCCAATGGGA
TTTAAGAGAAGGCGATCGGTGAAAAAGAACAGTTCAACTAATCAAACACT
TACCGAAGTTAGTGAAGACGAACTTAATGATGAACTCAACGATATCGTTC
CAACACAAGATCCCGACTTAACTCCAAACCAACTTCCGAGTTTATCTGAT
TCGCATGTTCCAATTGAGAACAGCATTTCAAGTCGGTCAGAAGACAAACA
TTTGACTGAGCTAGTTGATGCTGACTGTCACGAAGTGAAAAGTTGGTGGC
ATGTTCAAATAAATACAGACAAATCGCTTCTTGATAATGAAGACTCTTCT
TCTTACACTTCAAATGATGAATAATAATAAACCGCGCGTCTAAAAGACTT
ATTCCATTGTGATATTTAACATATATTTTCAGTTTTTATTACTAAAATAG
ATATCCATTTCATTTGCAAGAGTATGATGAAGACCTTTGCCATGGCGGAG
GAATTGTACATGAAATGAATGATATCTCACTAATTGCTCTGTCTGCCTTT
TGCTAATAAATATT

protein sequence of SMED30019733-orf-1

>SMED30019733-orf-1 ID=SMED30019733-orf-1|Name=SMED30019733-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1891bp
MHRSERKTSHTRETQPTLPGVEFATDDAGDLTSVNWVYTTWARCAFKIAA
LLSLASVSANTPETFKEYKWLFYVTYLLDIVVALLFTAEMFTKMKIKGII
RPSPYVIVRHLFFVKVSNNIENKRPHAYLRHFWGCFDTIMVICLWISITI
QTFELLKVIKCETPLDSCKELITFWQKYGLLSTLRSPRPLILTRVLRSFL
KFRLPQTRVKAILHRSTHQVYNVTVFLLFFMSLYAILGVQFFGDDINHHC
VLQSANESDIKITDLAIPDSFCNPKFKSGDSCPYSMKCVKIANSIEDEGG
YAGFGTFHFSFFTVYQAASQEGWVFIMYRAMDCLPQWKGVSYFISMIFFL
AWLVKNVFIAILTETFAEIRVQFQQMWSPKNQTDADSSKIFQTDGQRWKL
VPVYESKPHGLAPKLFQEIVLKSTAFNVIIMLLVLANAIVAAGLHFNHDE
LTQTNGFYYAELVFTILFNIEAVFKIWCLGWKSYWYRSLHKFEFILCLGT
TVHCMWYRTQLTYFQVLRIFRLMKASPMLEDFCFKIFGSGKKLGILILFT
SCLLIITSSVSLQLFCSIQIYEPKFDRFSNFPKAFLQIFTLVTEEGWIEV
MTRAMIDAKKIPNDWAQQLFSTFSGIYFILINLIFSFAFMSMFQILTQKG
WVIVMHDTMDMAKHRGLNALVAIYFVFYHLFVTLIVLSLFVAVILDNLEL
EEDIKKLKQLKLREMSAETQQKLPMRLRIFEKFPNRPQMIKPARLLSDFL
IPKIRDSFMRQFAQLPTLEEENESDEMIAAAVSGVGVSSLPRALSIEIKR
QIRGLKGNDKLNAIIYLINESNKTRMIEQPIIYPTRSLLSTQHQIRTERR
NLRNRMAATTMSINQKPRLNGEIRNMDFETNRKTEEANHFDIKILQQKAE
QAEIKRNQQVDDLRENHPYFDKPLFTIGRESQFRQLCRMLVEAQYKPDIN
SENPEKQTFYKLQKFFGLVTYLDWVMIFVTTTSCISMAFETPTKRVMNTI
ELKVAEYIFFVAMTIEMALKVLANGFIFTPKAVVRDFGGVLDFFIYIICI
IFVAYMIRVDTIGSGSGKQILMILRCLRPLRIFCLVPHMRRVVFELVRGF
REILMVSVLLVVFMFTFAVYGVHIFGGKLAICNDPTKTEKKDCVGVFDRK
ISVTKLKLSGDSPSFLVPRVWANPRNFNFDNIGNAMLTLFEVLSLEGWVE
IRDVIKARVGRINVIYIHLFVFIGCLIGLTLFVGVVIANYSENKGTALLT
VDQRRWLDLKGRIKLTQPLHIPPRPKMRQDSTQNRTDNNAINENSFDNRV
IKVRCWVYDLTQHIYFKRVSAIMVLINCIFLYFPWNNDDEYGMKRSKILA
SFNVTWTFIFCIECALKITALSFIGYWQSKRNIYDMVVTFLSLIWVFVHI
SVQDNHNSRVMSNNFGWMTVLLRFFSIAGKHVTLKMLMQTVLMSMFKSLF
VIIAMFLLMLVYALAGIILFGSVKYGENLGRHANFHNTFRSIALLFRIVT
GEDWNKIMHDCMVQPPFCTYRENFWQSDCGNFQASLIYFCSFYIMITYIM
LNVLVAIIMENFSLFYSNDEDAIISYNDIRNFQQAWNSIDVNRKGFIKAF
YVRFLLRLIPKDRVGFDFTKKKDQQLFKEMCYEVELLRGGKDKEVSFHDV
LTMLAYRSVDISKTLQLEELLAREELEYAIEEEVARQTIATWIERCIFRN
RQKHGDLKFGLRESNEMVIPIFDDKKEGLGLDRSRKISSGAYQTKFLSLP
TLDGRQNTSDGSLPSSGITIGRLNDHLKNQPMGFKRRRSVKKNSSTNQTL
TEVSEDELNDELNDIVPTQDPDLTPNQLPSLSDSHVPIENSISSRSEDKH
LTELVDADCHEVKSWWHVQINTDKSLLDNEDSSSYTSNDE*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000020	protonephridia
PLANA:0000418	head

Vocabulary: **INTERPRO**
Term	Definition
IPR028823	NALCN
IPR027359	Volt_channel_dom_sf
IPR005821	Ion_trans_dom
IPR011528	NERD
IPR019774	Aromatic-AA_hydroxylase_C

Vocabulary: **biological process**
Term	Definition
GO:0006811	ion transport
GO:0055085	transmembrane transport
GO:0055114	oxidation-reduction process
GO:0034220	ion transmembrane transport
GO:0098655	cation transmembrane transport

Vocabulary: **cellular component**
Term	Definition
GO:0016020	membrane
GO:0016021	integral component of membrane

Vocabulary: **molecular function**
Term	Definition
GO:0005216	ion channel activity
GO:0016714	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen
GO:0005261	cation channel activity

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 892..912
None	No IPR available	GENE3D	G3DSA:1.10.287.70		coord: 283..371 e-value: 8.5E-11 score: 43.7 coord: 528..635 e-value: 2.2E-7 score: 32.7 coord: 1432..1562 e-value: 3.5E-21 score: 77.2 coord: 636..702 e-value: 2.7E-9 score: 38.8
None	No IPR available	GENE3D	G3DSA:1.10.238.10		coord: 1563..1692 e-value: 1.7E-8 score: 36.3
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 1781..1807
None	No IPR available	SUPERFAMILY	SSF81324	Voltage-gated potassium channels	coord: 1313..1563
None	No IPR available	SUPERFAMILY	SSF81324	Voltage-gated potassium channels	coord: 970..1242
None	No IPR available	SUPERFAMILY	SSF81324	Voltage-gated potassium channels	coord: 52..369
None	No IPR available	SUPERFAMILY	SSF81324	Voltage-gated potassium channels	coord: 424..643
None	No IPR available	TMHMM	TMhelix		coord: 966..988
None	No IPR available	TMHMM	TMhelix		coord: 492..514
None	No IPR available	TMHMM	TMhelix		coord: 1536..1558
None	No IPR available	TMHMM	TMhelix		coord: 1383..1402
None	No IPR available	TMHMM	TMhelix		coord: 1415..1434
None	No IPR available	TMHMM	TMhelix		coord: 457..479
None	No IPR available	TMHMM	TMhelix		coord: 1314..1336
None	No IPR available	TMHMM	TMhelix		coord: 128..150
None	No IPR available	TMHMM	TMhelix		coord: 619..641
None	No IPR available	TMHMM	TMhelix		coord: 1215..1237
None	No IPR available	TMHMM	TMhelix		coord: 1356..1378
None	No IPR available	TMHMM	TMhelix		coord: 1103..1125
None	No IPR available	TMHMM	TMhelix		coord: 1449..1471
None	No IPR available	TMHMM	TMhelix		coord: 669..691
None	No IPR available	TMHMM	TMhelix		coord: 425..447
None	No IPR available	TMHMM	TMhelix		coord: 220..242
None	No IPR available	TMHMM	TMhelix		coord: 1037..1059
None	No IPR available	TMHMM	TMhelix		coord: 70..92
None	No IPR available	TMHMM	TMhelix		coord: 543..565
None	No IPR available	TMHMM	TMhelix		coord: 340..362
None	No IPR available	TMHMM	TMhelix		coord: 1008..1030
IPR005821	Ion transport domain	PFAM	PF00520	Ion_trans	coord: 1314..1568 e-value: 1.6E-32 score: 112.7 coord: 51..372 e-value: 9.9E-26 score: 90.4 coord: 971..1243 e-value: 1.6E-39 score: 135.6 coord: 424..642 e-value: 1.7E-22 score: 79.9
IPR027359	Voltage-dependent channel domain superfamily	GENE3D	G3DSA:1.20.120.350		coord: 1304..1428 e-value: 5.5E-13 score: 51.1 coord: 33..200 e-value: 6.6E-7 score: 31.6 coord: 966..1087 e-value: 5.7E-14 score: 54.3 coord: 417..527 e-value: 1.3E-15 score: 59.6
IPR028823	Sodium leak channel non-selective protein	PANTHER	PTHR46141	FAMILY NOT NAMED	coord: 635..1866 coord: 6..634