2-amino-3-carboxymuconate-6-semialdehyde decarboxylase

Overview
Name2-amino-3-carboxymuconate-6-semialdehyde decarboxylase
Smed IDSMED30019697
Length (bp)1258
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase (SMED30019697) t-SNE clustered cells

Violin plots show distribution of expression levels for 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase (SMED30019697) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase (SMED30019697) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase (SMED30019697) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30019697

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 5

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
gutSMED30019697h1SMcG0016841 dd_Smed_v4_8766_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30019697h1SMcG0016841 Contig49469newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30019697h1SMcG0016841 Contig49469uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
gutSMED30019697h1SMcG0016841 SMED30019697smed_20140614PMID:26457503
Tu et al., 2015		whole organism asexual adult colorimetric in situ hybridization evidence
parenchymaSMED30019697h1SMcG0016841 SMED30019697smed_20140614PMID:26457503
Tu et al., 2015		whole organism asexual adult colorimetric in situ hybridization evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase vs. Ensembl Human
Match: ACMSD (aminocarboxymuconate semialdehyde decarboxylase [Source:HGNC Symbol;Acc:HGNC:19288])

HSP 1 Score: 360.147 bits (923), Expect = 1.449e-122
Identity = 166/315 (52.70%), Postives = 229/315 (72.70%), Query Frame = 1 
Query:  130 QTKYGYRGWLKIKHDETTGLASLYKDTGEFFRLIKPNCWDLETRIIEMSQTSVDMQVLSTVPVMFNYWAKPKDTLDLCKFLNDDIANSVSKHPNKFIGLGTIPLQDPLLCVEELKRLKMTKGMHGIQIGTHVADYDFDNAFFDPVFKTCEDLDLSIFVHPWDMPSGKRYNKFWMPWLVGMPNETTIALLSFLMGGILLKYPKLKICFAHGGGSFPYTMGRIDHGYNVCPNLCATACNQCPSSFIGNFYTDSLVHNDQTLDFLVKVIGENKVCMGSDYPFPLGEHNPGSLIEE-SSFSKKTKDKLLAKNAAEFLGI 1071
            + ++GY GW++++H  + G A L KD G+ FR+++ NCWD E RI EM Q  V +Q LSTVPVMF+YWAKP+DTL+LC+ LN+D+A++V  +P +F+GLGT+P+Q P L V+E++R     G  G+QIGTHV ++D +     PV+   E L  S+FVHPWDM    R  K+W+PWLVGMP ETTIA+ S +MGG+  K+PKLK+CFAHGGG+FP+T+GRI HG+++ P+LCA      P  ++G+FYTD+LVH+  +L  L  VIG++KV +G+DYPFPLGE  PG LIE    F ++TK+KL A NA  FLG+
Sbjct:   18 KKRFGYGGWVQLQH-HSKGEAKLLKD-GKVFRVVRENCWDPEVRIREMDQKGVTVQALSTVPVMFSYWAKPEDTLNLCQLLNNDLASTVVSYPRRFVGLGTLPMQAPELAVKEMERCVKELGFPGVQIGTHVNEWDLNAQELFPVYAAAERLKCSLFVHPWDMQMDGRMAKYWLPWLVGMPAETTIAICSMIMGGVFEKFPKLKVCFAHGGGAFPFTVGRISHGFSMRPDLCAQDNPMNPKKYLGSFYTDALVHDPLSLKLLTDVIGKDKVILGTDYPFPLGELEPGKLIESMEEFDEETKNKLKAGNALAFLGL 330
[Close]
BLAST of 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase vs. Ensembl Human
Match: ACMSD (aminocarboxymuconate semialdehyde decarboxylase [Source:HGNC Symbol;Acc:HGNC:19288])

HSP 1 Score: 286.96 bits (733), Expect = 1.406e-94
Identity = 131/247 (53.04%), Postives = 180/247 (72.87%), Query Frame = 1 
Query:  334 AKPKDTLDLCKFLNDDIANSVSKHPNKFIGLGTIPLQDPLLCVEELKRLKMTKGMHGIQIGTHVADYDFDNAFFDPVFKTCEDLDLSIFVHPWDMPSGKRYNKFWMPWLVGMPNETTIALLSFLMGGILLKYPKLKICFAHGGGSFPYTMGRIDHGYNVCPNLCATACNQCPSSFIGNFYTDSLVHNDQTLDFLVKVIGENKVCMGSDYPFPLGEHNPGSLIEE-SSFSKKTKDKLLAKNAAEFLGI 1071
            AKP+DTL+LC+ LN+D+A++V  +P +F+GLGT+P+Q P L V+E++R     G  G+QIGTHV ++D +     PV+   E L  S+FVHPWDM    R  K+W+PWLVGMP ETTIA+ S +MGG+  K+PKLK+CFAHGGG+FP+T+GRI HG+++ P+LCA      P  ++G+FYTD+LVH+  +L  L  VIG++KV +G+DYPFPLGE  PG LIE    F ++TK+KL A NA  FLG+
Sbjct:   26 AKPEDTLNLCQLLNNDLASTVVSYPRRFVGLGTLPMQAPELAVKEMERCVKELGFPGVQIGTHVNEWDLNAQELFPVYAAAERLKCSLFVHPWDMQMDGRMAKYWLPWLVGMPAETTIAICSMIMGGVFEKFPKLKVCFAHGGGAFPFTVGRISHGFSMRPDLCAQDNPMNPKKYLGSFYTDALVHDPLSLKLLTDVIGKDKVILGTDYPFPLGELEPGKLIESMEEFDEETKNKLKAGNALAFLGL 272
[Close]
BLAST of 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase vs. Ensembl Celegans
Match: acsd-1 (2-amino-3-carboxymuconate-6-semialdehyde decarboxylase [Source:UniProtKB/Swiss-Prot;Acc:Q8T8B9])

HSP 1 Score: 323.553 bits (828), Expect = 2.416e-108
Identity = 153/322 (47.52%), Postives = 224/322 (69.57%), Query Frame = 1 
Query:  130 QTKYGYRGWLKIKHDETTGLASLYKDTGEFFRLIKPNCWDLETRIIEMSQTSVDMQVLSTVPVMFNYWAKPKDTLDLCKFLNDDIANSVSKHPNKFIGLGTIPLQDPLLCVEELKRLKMTKGMHGIQIGTHVADYDFDNAFFDPVFKTCEDLDLSIFVHPWDMPS-GKRYNKFWMPWLVGMPNETTIALLSFLMGGILLKYPKLKICFAHGGGSFPYTMGRIDHGYNVCPNLCATACNQCPSSFIGNFYTDSLVHNDQTLDFLVKVIGENKVCMGSDYPFPLGEHNPGSLIEE-SSFSKKTKDKLLAKNAAEFLGITDPMLF 1089
            Q K+GY G++++ H E  G   + KD G+ FR+++PNC+D ETRI +M++ +V++Q LSTVPVMF+YWAKP DT  + +F+NDD+     K P++ + LGT+P+ D    VEE+KR  ++ G+ G ++G+HVA+   D+  F P++K CE+L + +FVHPWDM     R +K+WMPWLVGMP+ET  A+ S LMG IL+ +PKLK+CFAHGGG++P   GR+ HG+NV P+LCA  C   P+   G  +TDSLVH+ + L+ L+  +G+  + +G+DYPFPLGE   G ++EE   FS K ++ LL KNA + L I + +LF
Sbjct:   30 QEKFGYPGFVRLDHKED-GTTHMVKD-GKLFRVVEPNCFDTETRIADMNRANVNVQCLSTVPVMFSYWAKPADTEIVARFVNDDLLAECQKFPDRLVPLGTLPMNDVQRAVEEVKRC-VSMGIKGFEVGSHVAEKSLDHRDFWPLYKICEELSVVLFVHPWDMHMWDGRLDKYWMPWLVGMPSETAQAICSVLMGNILVLFPKLKLCFAHGGGAYPQIRGRVSHGWNVRPDLCAGKCKVAPNKLDGLLWTDSLVHDPKALELLINTVGKEHIVLGTDYPFPLGELEVGRVVEEYKPFSAKDREDLLWKNAVKMLDIDENLLF 348
[Close]
BLAST of 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase vs. Ensembl Celegans
Match: acsd-1 (2-amino-3-carboxymuconate-6-semialdehyde decarboxylase [Source:UniProtKB/Swiss-Prot;Acc:Q8T8B9])

HSP 1 Score: 295.434 bits (755), Expect = 1.253e-96
Identity = 153/371 (41.24%), Postives = 224/371 (60.38%), Query Frame = 1 
Query:  130 QTKYGYRGWLKIKHDETTGLASLYKDTGEFFRLIKPNCWDLETRIIEMSQTSVDMQVLSTVPVMFNYWAKPKDTLDLCKFLNDDIANSVSKHPNKFIGLGTIPLQDPLLCVE--------------------ELKRLKMTKGMHGIQIGTHVADYDFDNAFFDPVFK-----------------------------TCEDLDLSIFVHPWDMPS-GKRYNKFWMPWLVGMPNETTIALLSFLMGGILLKYPKLKICFAHGGGSFPYTMGRIDHGYNVCPNLCATACNQCPSSFIGNFYTDSLVHNDQTLDFLVKVIGENKVCMGSDYPFPLGEHNPGSLIEE-SSFSKKTKDKLLAKNAAEFLGITDPMLF 1089
            Q K+GY G++++ H E  G   + KD G+ FR+++PNC+D ETRI +M++ +V++Q LSTVPVMF+YWAKP DT  + +F+NDD+     K P++ + LGT+P+ D    VE                    E+KR  ++ G+ G ++G+HVA+   D+  F P++K                              CE+L + +FVHPWDM     R +K+WMPWLVGMP+ET  A+ S LMG IL+ +PKLK+CFAHGGG++P   GR+ HG+NV P+LCA  C   P+   G  +TDSLVH+ + L+ L+  +G+  + +G+DYPFPLGE   G ++EE   FS K ++ LL KNA + L I + +LF
Sbjct:   30 QEKFGYPGFVRLDHKED-GTTHMVKD-GKLFRVVEPNCFDTETRIADMNRANVNVQCLSTVPVMFSYWAKPADTEIVARFVNDDLLAECQKFPDRLVPLGTLPMNDVQRAVEIFGKRIFFFEIWSPAKKSPEEVKRC-VSMGIKGFEVGSHVAEKSLDHRDFWPLYKLTESFKLSTIMPGFCEFFENWGLTTKTPGICEELSVVLFVHPWDMHMWDGRLDKYWMPWLVGMPSETAQAICSVLMGNILVLFPKLKLCFAHGGGAYPQIRGRVSHGWNVRPDLCAGKCKVAPNKLDGLLWTDSLVHDPKALELLINTVGKEHIVLGTDYPFPLGELEVGRVVEEYKPFSAKDREDLLWKNAVKMLDIDENLLF 397
[Close]
BLAST of 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase vs. Ensembl Zebrafish
Match: acmsd (aminocarboxymuconate semialdehyde decarboxylase [Source:ZFIN;Acc:ZDB-GENE-070410-103])

HSP 1 Score: 362.459 bits (929), Expect = 1.203e-123
Identity = 170/316 (53.80%), Postives = 229/316 (72.47%), Query Frame = 1 
Query:  130 QTKYGYRGWLKIKHDETTGLASLYKDTGEFFRLIKPNCWDLETRIIEMSQTSVDMQVLSTVPVMFNYWAKPKDTLDLCKFLNDDIANSVSKHPNKFIGLGTIPLQDPLLCVEELKRLKMTKGMHGIQIGTHVADYDFDNAFFDPVFKTCEDLDLSIFVHPWDMPSGKRYNKFWMPWLVGMPNETTIALLSFLMGGILLKYPKLKICFAHGGGSFPYTMGRIDHGYNVCPNLCATACNQCPSSFIGNFYTDSLVHNDQTLDFLVKVIGENKVCMGSDYPFPLGEHNPGSLIEE-SSFSKKTKDKLLAKNAAEFLGIT 1074
            + +YGY G++++ H    G A + KD G+ FR+I+ NCWD E RI +M +  V +Q LSTVPVMF+YWAKP DTLDLC  LNDD+A +V ++P +F+GLGT+P+Q P L V+E++R     G  G+QIG+H+  +D +     PV+   E+LD S+FVHPWDM +  R  K+W+PWLVGMP ETT+A+ S L GG+  ++PKLK+CFAHGGG+FPYT+GRI+HG+ V P+LCAT     P  ++G+FYTDSLVH+  +L  LV VIG++KV +G+DYPFPLGE  PG+LIE    F    KDKLLA NA +FLG+T
Sbjct:   18 KQRYGYGGFVQLHH-HCKGEAKMMKD-GKLFRVIQENCWDPEARIRDMEKHGVTVQALSTVPVMFSYWAKPNDTLDLCGILNDDLAATVKQYPKRFVGLGTLPMQAPDLAVQEMRRCVNQLGFPGVQIGSHINTWDLNAPELFPVYAAAEELDCSLFVHPWDMQTDGRMAKYWLPWLVGMPAETTMAICSMLFGGVFERFPKLKVCFAHGGGAFPYTVGRIEHGFKVRPDLCATDNKINPRKYLGSFYTDSLVHDPLSLKLLVDVIGKDKVMLGTDYPFPLGELEPGTLIESMDEFDSLLKDKLLAGNALDFLGLT 331
[Close]
BLAST of 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase vs. Ensembl Zebrafish
Match: acmsd (aminocarboxymuconate semialdehyde decarboxylase [Source:ZFIN;Acc:ZDB-GENE-070410-103])

HSP 1 Score: 362.459 bits (929), Expect = 1.203e-123
Identity = 170/316 (53.80%), Postives = 229/316 (72.47%), Query Frame = 1 
Query:  130 QTKYGYRGWLKIKHDETTGLASLYKDTGEFFRLIKPNCWDLETRIIEMSQTSVDMQVLSTVPVMFNYWAKPKDTLDLCKFLNDDIANSVSKHPNKFIGLGTIPLQDPLLCVEELKRLKMTKGMHGIQIGTHVADYDFDNAFFDPVFKTCEDLDLSIFVHPWDMPSGKRYNKFWMPWLVGMPNETTIALLSFLMGGILLKYPKLKICFAHGGGSFPYTMGRIDHGYNVCPNLCATACNQCPSSFIGNFYTDSLVHNDQTLDFLVKVIGENKVCMGSDYPFPLGEHNPGSLIEE-SSFSKKTKDKLLAKNAAEFLGIT 1074
            + +YGY G++++ H    G A + KD G+ FR+I+ NCWD E RI +M +  V +Q LSTVPVMF+YWAKP DTLDLC  LNDD+A +V ++P +F+GLGT+P+Q P L V+E++R     G  G+QIG+H+  +D +     PV+   E+LD S+FVHPWDM +  R  K+W+PWLVGMP ETT+A+ S L GG+  ++PKLK+CFAHGGG+FPYT+GRI+HG+ V P+LCAT     P  ++G+FYTDSLVH+  +L  LV VIG++KV +G+DYPFPLGE  PG+LIE    F    KDKLLA NA +FLG+T
Sbjct:   18 KQRYGYGGFVQLHH-HCKGEAKMMKD-GKLFRVIQENCWDPEARIRDMEKHGVTVQALSTVPVMFSYWAKPNDTLDLCGILNDDLAATVKQYPKRFVGLGTLPMQAPDLAVQEMRRCVNQLGFPGVQIGSHINTWDLNAPELFPVYAAAEELDCSLFVHPWDMQTDGRMAKYWLPWLVGMPAETTMAICSMLFGGVFERFPKLKVCFAHGGGAFPYTVGRIEHGFKVRPDLCATDNKINPRKYLGSFYTDSLVHDPLSLKLLVDVIGKDKVMLGTDYPFPLGELEPGTLIESMDEFDSLLKDKLLAGNALDFLGLT 331
[Close]
BLAST of 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase vs. Ensembl Xenopus
Match: gid4 (GID complex subunit 4 homolog [Source:Xenbase;Acc:XB-GENE-961120])

HSP 1 Score: 378.637 bits (971), Expect = 8.832e-130
Identity = 176/315 (55.87%), Postives = 232/315 (73.65%), Query Frame = 1 
Query:  130 QTKYGYRGWLKIKHDETTGLASLYKDTGEFFRLIKPNCWDLETRIIEMSQTSVDMQVLSTVPVMFNYWAKPKDTLDLCKFLNDDIANSVSKHPNKFIGLGTIPLQDPLLCVEELKRLKMTKGMHGIQIGTHVADYDFDNAFFDPVFKTCEDLDLSIFVHPWDMPSGKRYNKFWMPWLVGMPNETTIALLSFLMGGILLKYPKLKICFAHGGGSFPYTMGRIDHGYNVCPNLCATACNQCPSSFIGNFYTDSLVHNDQTLDFLVKVIGENKVCMGSDYPFPLGEHNPGSLIEE-SSFSKKTKDKLLAKNAAEFLGI 1071
            + +YGY GW++++H    G A + KD G  FR+++ NCWD + R+ EM +T V +Q LSTVPVMF+YWAKP+DTLDL  FLNDD+A +V K+P +F+GLGT+P+Q P L V+E+ R     G  G+QIG+H+  +D ++    PV+   E+LD SIFVHPWDM  G R +K+W+PWLVGMP ETT A+   ++GGIL K+PKLK+CFAHGGG+FPYT+GRIDHG+NV P+LCA      P S++G FYTDSLVH+   +  LV VIG++KV +GSDYPFPLGEH PG LIE    F +K K+KLLA NA +FLG+
Sbjct:   18 RERYGYDGWIQMQH-HCQGEAKMMKD-GNIFRVVQANCWDPDVRLQEMDRTGVTVQALSTVPVMFSYWAKPQDTLDLACFLNDDLAATVKKYPKRFVGLGTLPMQCPELAVQEMHRCVKELGFPGVQIGSHINQWDLNSPELHPVYAAAEELDCSIFVHPWDMELGGRMSKYWLPWLVGMPAETTTAICCMVLGGILEKFPKLKVCFAHGGGAFPYTVGRIDHGFNVRPDLCAVDNTTAPYSYLGKFYTDSLVHDPNAMKLLVDVIGKDKVLLGSDYPFPLGEHVPGQLIESMDDFDQKLKEKLLAGNALDFLGL 330
[Close]
BLAST of 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase vs. Ensembl Xenopus
Match: gid4 (GID complex subunit 4 homolog [Source:Xenbase;Acc:XB-GENE-961120])

HSP 1 Score: 360.533 bits (924), Expect = 6.199e-123
Identity = 167/303 (55.12%), Postives = 221/303 (72.94%), Query Frame = 1 
Query:  130 QTKYGYRGWLKIKHDETTGLASLYKDTGEFFRLIKPNCWDLETRIIEMSQTSVDMQVLSTVPVMFNYWAKPKDTLDLCKFLNDDIANSVSKHPNKFIGLGTIPLQDPLLCVEELKRLKMTKGMHGIQIGTHVADYDFDNAFFDPVFKTCEDLDLSIFVHPWDMPSGKRYNKFWMPWLVGMPNETTIALLSFLMGGILLKYPKLKICFAHGGGSFPYTMGRIDHGYNVCPNLCATACNQCPSSFIGNFYTDSLVHNDQTLDFLVKVIGENKVCMGSDYPFPLGEHNPGSLIEE-SSFSKKTKDK 1035
            + +YGY GW++++H    G A + KD G  FR+++ NCWD + R+ EM +T V +Q LSTVPVMF+YWAKP+DTLDL  FLNDD+A +V K+P +F+GLGT+P+Q P L V+E+ R     G  G+QIG+H+  +D ++    PV+   E+LD SIFVHPWDM  G R +K+W+PWLVGMP ETT A+   ++GGIL K+PKLK+CFAHGGG+FPYT+GRIDHG+NV P+LCA      P S++G FYTDSLVH+   +  LV VIG++KV +GSDYPFPLGEH PG LIE    F +K K +
Sbjct:   18 RERYGYDGWIQMQH-HCQGEAKMMKD-GNIFRVVQANCWDPDVRLQEMDRTGVTVQALSTVPVMFSYWAKPQDTLDLACFLNDDLAATVKKYPKRFVGLGTLPMQCPELAVQEMHRCVKELGFPGVQIGSHINQWDLNSPELHPVYAAAEELDCSIFVHPWDMELGGRMSKYWLPWLVGMPAETTTAICCMVLGGILEKFPKLKVCFAHGGGAFPYTVGRIDHGFNVRPDLCAVDNTTAPYSYLGKFYTDSLVHDPNAMKLLVDVIGKDKVLLGSDYPFPLGEHVPGQLIESMDDFDQKLKRQ 318
[Close]
BLAST of 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase vs. Ensembl Xenopus
Match: gid4 (GID complex subunit 4 homolog [Source:Xenbase;Acc:XB-GENE-961120])

HSP 1 Score: 347.821 bits (891), Expect = 5.114e-118
Identity = 163/291 (56.01%), Postives = 210/291 (72.16%), Query Frame = 1 
Query:  172 DETTGLASLYKDTGEFFRLIKPNCWDLETRIIEMSQTSVDMQVLSTVPVMFNYWAKPKDTLDLCKFLNDDIANSVSKHPNKFIGLGTIPLQDPLLCVEELKRLKMTKGMHGIQIGTHVADYDFDNAFFDPVFKTCEDLDLSIFVHPWDMPSGKRYNKFWMPWLVGMPNETTIALLSFLMGGILLKYPKLKICFAHGGGSFPYTMGRIDHGYNVCPNLCATACNQCPSSFIGNFYTDSLVHNDQTLDFLVKVIGENKVCMGSDYPFPLGEHNPGSLIEE-SSFSKKTKDKLL 1041
            D   G A + KD G  FR+++ NCWD + R+ EM +T V +Q LSTVPVMF+YWAKP+DTLDL  FLNDD+A +V K+P +F+GLGT+P+Q P L V+E+ R     G  G+QIG+H+  +D ++    PV+   E+LD SIFVHPWDM  G R +K+W+PWLVGMP ETT A+   ++GGIL K+PKLK+CFAHGGG+FPYT+GRIDHG+NV P+LCA      P S++G FYTDSLVH+   +  LV VIG++KV +GSDYPFPLGEH PG LIE    F +K K K  
Sbjct:   16 DLREGEAKMMKD-GNIFRVVQANCWDPDVRLQEMDRTGVTVQALSTVPVMFSYWAKPQDTLDLACFLNDDLAATVKKYPKRFVGLGTLPMQCPELAVQEMHRCVKELGFPGVQIGSHINQWDLNSPELHPVYAAAEELDCSIFVHPWDMELGGRMSKYWLPWLVGMPAETTTAICCMVLGGILEKFPKLKVCFAHGGGAFPYTVGRIDHGFNVRPDLCAVDNTTAPYSYLGKFYTDSLVHDPNAMKLLVDVIGKDKVLLGSDYPFPLGEHVPGQLIESMDDFDQKLKVKFF 305
[Close]
BLAST of 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase vs. Ensembl Xenopus
Match: gid4 (GID complex subunit 4 homolog [Source:Xenbase;Acc:XB-GENE-961120])

HSP 1 Score: 320.857 bits (821), Expect = 9.539e-108
Identity = 146/268 (54.48%), Postives = 196/268 (73.13%), Query Frame = 1 
Query:  130 QTKYGYRGWLKIKHDETTGLASLYKDTGEFFRLIKPNCWDLETRIIEMSQTSVDMQVLSTVPVMFNYWAKPKDTLDLCKFLNDDIANSVSKHPNKFIGLGTIPLQDPLLCVEELKRLKMTKGMHGIQIGTHVADYDFDNAFFDPVFKTCEDLDLSIFVHPWDMPSGKRYNKFWMPWLVGMPNETTIALLSFLMGGILLKYPKLKICFAHGGGSFPYTMGRIDHGYNVCPNLCATACNQCPSSFIGNFYTDSLVHNDQTLDFLVKVIGE 933
            + +YGY GW++++H    G A + KD G  FR+++ NCWD + R+ EM +T V +Q LSTVPVMF+YWAKP+DTLDL  FLNDD+A +V K+P +F+GLGT+P+Q P L V+E+ R     G  G+QIG+H+  +D ++    PV+   E+LD SIFVHPWDM  G R +K+W+PWLVGMP ETT A+   ++GGIL K+PKLK+CFAHGGG+FPYT+GRIDHG+NV P+LCA      P S++G FYTDSLVH+   +  LV VIG+
Sbjct:   18 RERYGYDGWIQMQH-HCQGEAKMMKD-GNIFRVVQANCWDPDVRLQEMDRTGVTVQALSTVPVMFSYWAKPQDTLDLACFLNDDLAATVKKYPKRFVGLGTLPMQCPELAVQEMHRCVKELGFPGVQIGSHINQWDLNSPELHPVYAAAEELDCSIFVHPWDMELGGRMSKYWLPWLVGMPAETTTAICCMVLGGILEKFPKLKVCFAHGGGAFPYTVGRIDHGFNVRPDLCAVDNTTAPYSYLGKFYTDSLVHDPNAMKLLVDVIGK 283
[Close]
BLAST of 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase vs. Ensembl Xenopus
Match: gid4 (GID complex subunit 4 homolog [Source:Xenbase;Acc:XB-GENE-961120])

HSP 1 Score: 311.227 bits (796), Expect = 1.197e-103
Identity = 148/279 (53.05%), Postives = 196/279 (70.25%), Query Frame = 1 
Query:  151 GWLKIKHDET-TGLASLYKDTGEFFRLIKPNCWDLETRIIEMSQTSVDMQVLSTVPVMFNYWAKPKDTLDLCKFLNDDIANSVSKHPNKFIGLGTIPLQDPLLCVEELKRLKMTKGMHGIQIGTHVADYDFDNAFFDPVFKTCEDLDLSIFVHPWDMPSGKRYNKFWMPWLVGMPNETTIALLSFLMGGILLKYPKLKICFAHGGGSFPYTMGRIDHGYNVCPNLCATACNQCPSSFIGNFYTDSLVHNDQTLDFLVKVIG---ENKVCMGSDYPFPLG 975
            G  ++K  E   G A + KD G  FR+++ NCWD + R+ EM +T V +Q LSTVPVMF+YWAKP+DTLDL  FLNDD+A +V K+P +F+GLGT+P+Q P L V+E+ R     G  G+QIG+H+  +D ++    PV+   E+LD SIFVHPWDM  G R +K+W+PWLVGMP ETT A+   ++GGIL K+PKLK+CFAHGGG+FPYT+GRIDHG+NV P+LCA      P S++G FYTDSLVH+   +  LV VIG   + +    +D PFP G
Sbjct:    2 GCERVKMSERCRGEAKMMKD-GNIFRVVQANCWDPDVRLQEMDRTGVTVQALSTVPVMFSYWAKPQDTLDLACFLNDDLAATVKKYPKRFVGLGTLPMQCPELAVQEMHRCVKELGFPGVQIGSHINQWDLNSPELHPVYAAAEELDCSIFVHPWDMELGGRMSKYWLPWLVGMPAETTTAICCMVLGGILEKFPKLKVCFAHGGGAFPYTVGRIDHGFNVRPDLCAVDNTTAPYSYLGKFYTDSLVHDPNAMKLLVDVIGKVSQYRFNSLTDKPFPPG 279
[Close]
BLAST of 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase vs. Ensembl Mouse
Match: Acmsd (amino carboxymuconate semialdehyde decarboxylase [Source:MGI Symbol;Acc:MGI:2386323])

HSP 1 Score: 369.392 bits (947), Expect = 2.612e-126
Identity = 168/315 (53.33%), Postives = 234/315 (74.29%), Query Frame = 1 
Query:  130 QTKYGYRGWLKIKHDETTGLASLYKDTGEFFRLIKPNCWDLETRIIEMSQTSVDMQVLSTVPVMFNYWAKPKDTLDLCKFLNDDIANSVSKHPNKFIGLGTIPLQDPLLCVEELKRLKMTKGMHGIQIGTHVADYDFDNAFFDPVFKTCEDLDLSIFVHPWDMPSGKRYNKFWMPWLVGMPNETTIALLSFLMGGILLKYPKLKICFAHGGGSFPYTMGRIDHGYNVCPNLCATACNQCPSSFIGNFYTDSLVHNDQTLDFLVKVIGENKVCMGSDYPFPLGEHNPGSLIEE-SSFSKKTKDKLLAKNAAEFLGI 1071
            + ++GY GW++++  +  G A + KD G+ FR+I+ NCWD E RI EM+Q  V +Q LSTVPVMF+YWAKPKDTL+LC+FLN+D+A +V+++P +F+GLGT+P+Q P L VEE++R     G  GIQIG+H+  +D ++    P++   E L+ S+FVHPWDM    R  K+W+PWLVGMP+ETT+A+ S +MGG+  K+PKLK+CFAHGGG+FP+T+GRI HG+N+ P+LCA      P  ++G+FYTDSLVH+  +L  L  VIG++KV +G+DYPFPLGE  PG LIE  + F ++TKDKL A NA  FLG+
Sbjct:   18 EKRFGYGGWVQLQQ-QGKGEAKMIKD-GKLFRVIQQNCWDPEVRIREMNQKGVTVQALSTVPVMFSYWAKPKDTLELCQFLNNDLAATVARYPRRFVGLGTLPMQAPELAVEEMERCVKALGFPGIQIGSHINTWDLNDPELFPIYAAAERLNCSLFVHPWDMQMDGRMAKYWLPWLVGMPSETTMAICSMIMGGVFEKFPKLKVCFAHGGGAFPFTIGRIAHGFNMRPDLCAQDNPSDPRKYLGSFYTDSLVHDPLSLKLLTDVIGKDKVMLGTDYPFPLGEQEPGKLIESMAEFDEETKDKLTAGNALAFLGL 330
[Close]
BLAST of 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase vs. UniProt/SwissProt
Match: sp|Q8R519|ACMSD_MOUSE (2-amino-3-carboxymuconate-6-semialdehyde decarboxylase OS=Mus musculus OX=10090 GN=Acmsd PE=1 SV=2)

HSP 1 Score: 369.392 bits (947), Expect = 1.827e-125
Identity = 168/315 (53.33%), Postives = 234/315 (74.29%), Query Frame = 1 
Query:  130 QTKYGYRGWLKIKHDETTGLASLYKDTGEFFRLIKPNCWDLETRIIEMSQTSVDMQVLSTVPVMFNYWAKPKDTLDLCKFLNDDIANSVSKHPNKFIGLGTIPLQDPLLCVEELKRLKMTKGMHGIQIGTHVADYDFDNAFFDPVFKTCEDLDLSIFVHPWDMPSGKRYNKFWMPWLVGMPNETTIALLSFLMGGILLKYPKLKICFAHGGGSFPYTMGRIDHGYNVCPNLCATACNQCPSSFIGNFYTDSLVHNDQTLDFLVKVIGENKVCMGSDYPFPLGEHNPGSLIEE-SSFSKKTKDKLLAKNAAEFLGI 1071
            + ++GY GW++++  +  G A + KD G+ FR+I+ NCWD E RI EM+Q  V +Q LSTVPVMF+YWAKPKDTL+LC+FLN+D+A +V+++P +F+GLGT+P+Q P L VEE++R     G  GIQIG+H+  +D ++    P++   E L+ S+FVHPWDM    R  K+W+PWLVGMP+ETT+A+ S +MGG+  K+PKLK+CFAHGGG+FP+T+GRI HG+N+ P+LCA      P  ++G+FYTDSLVH+  +L  L  VIG++KV +G+DYPFPLGE  PG LIE  + F ++TKDKL A NA  FLG+
Sbjct:   18 EKRFGYGGWVQLQQ-QGKGEAKMIKD-GKLFRVIQQNCWDPEVRIREMNQKGVTVQALSTVPVMFSYWAKPKDTLELCQFLNNDLAATVARYPRRFVGLGTLPMQAPELAVEEMERCVKALGFPGIQIGSHINTWDLNDPELFPIYAAAERLNCSLFVHPWDMQMDGRMAKYWLPWLVGMPSETTMAICSMIMGGVFEKFPKLKVCFAHGGGAFPFTIGRIAHGFNMRPDLCAQDNPSDPRKYLGSFYTDSLVHDPLSLKLLTDVIGKDKVMLGTDYPFPLGEQEPGKLIESMAEFDEETKDKLTAGNALAFLGL 330
[Close]
BLAST of 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase vs. UniProt/SwissProt
Match: sp|Q8R5M5|ACMSD_RAT (2-amino-3-carboxymuconate-6-semialdehyde decarboxylase OS=Rattus norvegicus OX=10116 GN=Acmsd PE=1 SV=1)

HSP 1 Score: 366.696 bits (940), Expect = 2.120e-124
Identity = 167/315 (53.02%), Postives = 234/315 (74.29%), Query Frame = 1 
Query:  130 QTKYGYRGWLKIKHDETTGLASLYKDTGEFFRLIKPNCWDLETRIIEMSQTSVDMQVLSTVPVMFNYWAKPKDTLDLCKFLNDDIANSVSKHPNKFIGLGTIPLQDPLLCVEELKRLKMTKGMHGIQIGTHVADYDFDNAFFDPVFKTCEDLDLSIFVHPWDMPSGKRYNKFWMPWLVGMPNETTIALLSFLMGGILLKYPKLKICFAHGGGSFPYTMGRIDHGYNVCPNLCATACNQCPSSFIGNFYTDSLVHNDQTLDFLVKVIGENKVCMGSDYPFPLGEHNPGSLIEE-SSFSKKTKDKLLAKNAAEFLGI 1071
            + ++GY GW++++  +  G A + KD G+ FR+I+ NCWD E RI EM+Q  V +Q LSTVPVMF+YWAKPKDTL+LC+FLN+D+A +V+++P +F+GLGT+P+Q P L VEE++R     G  GIQIG+H+  +D ++    P++   E L+ S+FVHPWDM    R  K+W+PWLVGMP+ETT A+ S +MGG+  K+PKLK+CFAHGGG+FP+T+GRI HG+N+ P+LCA   +  P  ++G+FYTDSLVH+  +L  L  VIG+++V +G+DYPFPLGE  PG LIE  + F ++TKDKL A NA  FLG+
Sbjct:   18 EKRFGYGGWVQLQQ-QGKGEAKMMKD-GKVFRVIQQNCWDPEVRIREMNQKGVTVQALSTVPVMFSYWAKPKDTLELCQFLNNDLAATVARYPRRFVGLGTLPMQAPGLAVEEMERCVKELGFPGIQIGSHINMWDLNDPELFPIYTAAERLNCSLFVHPWDMQMDGRMAKYWLPWLVGMPSETTTAICSMIMGGVFEKFPKLKVCFAHGGGAFPFTIGRIAHGFNMRPDLCARDNSSDPRKYLGSFYTDSLVHDPLSLKLLTDVIGKDRVILGTDYPFPLGEQEPGKLIESMADFDEETKDKLTAGNALTFLGL 330
[Close]
BLAST of 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase vs. UniProt/SwissProt
Match: sp|Q0II68|ACMSD_BOVIN (2-amino-3-carboxymuconate-6-semialdehyde decarboxylase OS=Bos taurus OX=9913 GN=ACMSD PE=2 SV=1)

HSP 1 Score: 363.229 bits (931), Expect = 4.724e-123
Identity = 166/315 (52.70%), Postives = 228/315 (72.38%), Query Frame = 1 
Query:  130 QTKYGYRGWLKIKHDETTGLASLYKDTGEFFRLIKPNCWDLETRIIEMSQTSVDMQVLSTVPVMFNYWAKPKDTLDLCKFLNDDIANSVSKHPNKFIGLGTIPLQDPLLCVEELKRLKMTKGMHGIQIGTHVADYDFDNAFFDPVFKTCEDLDLSIFVHPWDMPSGKRYNKFWMPWLVGMPNETTIALLSFLMGGILLKYPKLKICFAHGGGSFPYTMGRIDHGYNVCPNLCATACNQCPSSFIGNFYTDSLVHNDQTLDFLVKVIGENKVCMGSDYPFPLGEHNPGSLIEE-SSFSKKTKDKLLAKNAAEFLGI 1071
            + ++GY GW++++H+   G A + KD G+ FR+++ NCWD E R+ EM QT V +Q LSTVPVMF+YWAKP+DTLDLC+ LN+D+A +++ HP +F+GLGT+P+Q P L V+E++R     G  G+QIG+H+ ++D +     PV+   E L+ S+FVHPWDM    R  K+W PWL+GMP ETT A+ S +MGG+  K+PKLK+CFAHGGGSFP+T+GRI HG+++ P+LCA      P  ++G+FYTDSLVH+   L  L  VIG++KV +G+DYPFPLGE  PG LIE    F  +TKDKL A NA EFLG+
Sbjct:   18 KKRFGYGGWVQLQHN-GKGEAKMLKD-GKVFRVVQENCWDPEARLREMDQTGVTVQALSTVPVMFSYWAKPQDTLDLCQLLNNDLAATIASHPRRFVGLGTLPMQAPELAVKEMERCVRKLGFPGVQIGSHINEWDLNARELFPVYAEAERLNCSLFVHPWDMQMDGRMAKYWFPWLIGMPAETTAAICSMIMGGVFEKFPKLKVCFAHGGGSFPFTVGRISHGFSMRPDLCAQDNPTNPKKYLGSFYTDSLVHDPLALKLLTDVIGKDKVILGTDYPFPLGELEPGKLIESMGEFDAETKDKLKAGNALEFLGL 330
[Close]
BLAST of 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase vs. UniProt/SwissProt
Match: sp|Q8TDX5|ACMSD_HUMAN (2-amino-3-carboxymuconate-6-semialdehyde decarboxylase OS=Homo sapiens OX=9606 GN=ACMSD PE=1 SV=1)

HSP 1 Score: 360.147 bits (923), Expect = 6.957e-122
Identity = 166/315 (52.70%), Postives = 229/315 (72.70%), Query Frame = 1 
Query:  130 QTKYGYRGWLKIKHDETTGLASLYKDTGEFFRLIKPNCWDLETRIIEMSQTSVDMQVLSTVPVMFNYWAKPKDTLDLCKFLNDDIANSVSKHPNKFIGLGTIPLQDPLLCVEELKRLKMTKGMHGIQIGTHVADYDFDNAFFDPVFKTCEDLDLSIFVHPWDMPSGKRYNKFWMPWLVGMPNETTIALLSFLMGGILLKYPKLKICFAHGGGSFPYTMGRIDHGYNVCPNLCATACNQCPSSFIGNFYTDSLVHNDQTLDFLVKVIGENKVCMGSDYPFPLGEHNPGSLIEE-SSFSKKTKDKLLAKNAAEFLGI 1071
            + ++GY GW++++H  + G A L KD G+ FR+++ NCWD E RI EM Q  V +Q LSTVPVMF+YWAKP+DTL+LC+ LN+D+A++V  +P +F+GLGT+P+Q P L V+E++R     G  G+QIGTHV ++D +     PV+   E L  S+FVHPWDM    R  K+W+PWLVGMP ETTIA+ S +MGG+  K+PKLK+CFAHGGG+FP+T+GRI HG+++ P+LCA      P  ++G+FYTD+LVH+  +L  L  VIG++KV +G+DYPFPLGE  PG LIE    F ++TK+KL A NA  FLG+
Sbjct:   18 KKRFGYGGWVQLQH-HSKGEAKLLKD-GKVFRVVRENCWDPEVRIREMDQKGVTVQALSTVPVMFSYWAKPEDTLNLCQLLNNDLASTVVSYPRRFVGLGTLPMQAPELAVKEMERCVKELGFPGVQIGTHVNEWDLNAQELFPVYAAAERLKCSLFVHPWDMQMDGRMAKYWLPWLVGMPAETTIAICSMIMGGVFEKFPKLKVCFAHGGGAFPFTVGRISHGFSMRPDLCAQDNPMNPKKYLGSFYTDALVHDPLSLKLLTDVIGKDKVILGTDYPFPLGELEPGKLIESMEEFDEETKNKLKAGNALAFLGL 330
[Close]
BLAST of 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase vs. UniProt/SwissProt
Match: sp|Q54LN9|ACMSD_DICDI (2-amino-3-carboxymuconate-6-semialdehyde decarboxylase OS=Dictyostelium discoideum OX=44689 GN=acmsd PE=3 SV=1)

HSP 1 Score: 341.273 bits (874), Expect = 4.636e-114
Identity = 162/318 (50.94%), Postives = 223/318 (70.13%), Query Frame = 1 
Query:  130 QTKYGYRGWLKIKHDETTGLASLYKDTGEFFRLIKPNCWDLETRIIEMSQTSVDMQVLSTVPVMFNYWAKPKDTLDLCKFLNDDIANSVSKHPNKFIGLGTIPLQDPLLCVEELKRLKMTKGMHGIQIGTHVADYDFDNAFFDPVFKTCEDLDLSIFVHPWDMPSGKRYNKFWMPWLVGMPNETTIALLSFLMGGILLKYPKLKICFAHGGGSFPYTMGRIDHGYNVCPNLCATACNQCPSSFIGNFYTDSLVHNDQTLDFLVKVIGENKVCMGSDYPFPLGEHNPGSLIEE-SSFSKKTKDKLLAKNAAEFLGITDP 1080
            + KYGY GW+ + H   +  A +  D G+FFR I  NCWD + RI E+++  VD+QVLSTVPVMF YWAKP+D LDL ++LND IA  VS++P +FIGLG++P+Q     ++EL+R  +  G+ GIQIG++V   + D+    P+F+ CE L  ++F+HPW+M    R  ++W+PWLVGMP ET +A+ S + GG+  + P LK+CFAHGGGSFP+T+GRI+HG+N  P+LCA      P  +IG F+ DSLVH+++ L FLV ++GE KV +G+DYPFPLGE  PG LIE    FS+ TK+ LL  NA EFLG+ DP
Sbjct:   41 KEKYGYGGWVSLDH-HCSCKAKMMID-GKFFREIDSNCWDPDVRIQELNRDDVDIQVLSTVPVMFGYWAKPQDALDLAQYLNDHIAQVVSENPKRFIGLGSLPMQCTESSIQELRRCILELGLPGIQIGSNVNGKNLDDPSLFPIFEECEKLGAAVFIHPWEMVGKDRMPQYWLPWLVGMPAETCLAICSMIFGGVFQRLPNLKVCFAHGGGSFPFTIGRIEHGFNARPDLCAVVNPINPREYIGKFWVDSLVHDEEALKFLVNLMGEKKVTLGTDYPFPLGELVPGQLIESIKEFSETTKENLLGGNALEFLGL-DP 355
[Close]
BLAST of 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase vs. TrEMBL
Match: A0A210PRF3 (2-amino-3-carboxymuconate-6-semialdehyde decarboxylase OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT19801 PE=3 SV=1)

HSP 1 Score: 392.504 bits (1007), Expect = 4.847e-132
Identity = 180/314 (57.32%), Postives = 233/314 (74.20%), Query Frame = 1 
Query:  130 QTKYGYRGWLKIKHDETTGLASLYKDTGEFFRLIKPNCWDLETRIIEMSQTSVDMQVLSTVPVMFNYWAKPKDTLDLCKFLNDDIANSVSKHPNKFIGLGTIPLQDPLLCVEELKRLKMTKGMHGIQIGTHVADYDFDNAFFDPVFKTCEDLDLSIFVHPWDMPSGKRYNKFWMPWLVGMPNETTIALLSFLMGGILLKYPKLKICFAHGGGSFPYTMGRIDHGYNVCPNLCATACNQCPSSFIGNFYTDSLVHNDQTLDFLVKVIGENKVCMGSDYPFPLGEHNPGSLIEESSFSKKTKDKLLAKNAAEFLGI 1071
            + KYGY GWL++ H +  G A++ KD G+ FR++  NCW  E RI +M  T V +Q LSTVPVMF+YWAKP+DTLDLC+ LN+D+A +V K P++F+GLGT+PLQ P L V+EL R K   G  G+QIG+HV +++ D     PVF   E+ D++IFVHPWDM    R +K+W+PWLVGMP ET  A+   LMGG+L ++P+LK+CFAHGGGSFPYT+GR+ HGY+V P+LCAT CN  P +++G FYTD LVH+ + L  LV +IGE+KV MGSDYPFPLGEH+PG LIE+  F    KDKLLA NA EFLG+
Sbjct:   18 KEKYGYGGWLQLHH-KCEGKANMMKD-GKLFRVVDDNCWSPEARIKDMDTTGVTVQALSTVPVMFSYWAKPEDTLDLCQILNNDLAKTVKKFPDRFVGLGTLPLQAPDLAVQELVRCKTELGFTGVQIGSHVNEWNLDAKELRPVFAAAEEHDVAIFVHPWDMEMSGRMSKYWLPWLVGMPAETATAICCMLMGGVLEQFPRLKVCFAHGGGSFPYTVGRVQHGYDVRPDLCATECNVSPQNYLGKFYTDGLVHDSEALKLLVTIIGEDKVIMGSDYPFPLGEHHPGKLIEKMKFDDTLKDKLLAGNACEFLGL 329
[Close]
BLAST of 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase vs. TrEMBL
Match: A0A2P2HYE6 (2-amino-3-carboxymuconate-6-semialdehyde decarboxylase (Fragment) OS=Hirondellea gigas OX=1518452 PE=2 SV=1)

HSP 1 Score: 389.037 bits (998), Expect = 1.098e-130
Identity = 183/322 (56.83%), Postives = 233/322 (72.36%), Query Frame = 1 
Query:  130 QTKYGYRGWLKIKH--DETTGLASLYKDTGEFFRLIKPNCWDLETRIIEMSQTSVDMQVLSTVPVMFNYWAKPKDTLDLCKFLNDDIANSVSKHPNKFIGLGTIPLQDPLLCVEELKRLKMTKGMHGIQIGTHVADYDFDNAFFDPVFKTCEDLDLSIFVHPWDMPSGKRYNKFWMPWLVGMPNETTIALLSFLMGGILLKYPKLKICFAHGGGSFPYTMGRIDHGYNVCPNLCATACNQCPSSFIGNFYTDSLVHNDQTLDFLVKVIGENKVCMGSDYPFPLGEHNPGSLIEESSFSKKTKDKLLAKNAAEFLGITDPMLF 1089
            + +YGY G+++++    E  G  +     G+ FR++  NCW   TR+ EM +T V  QVLSTVPVMF+YWA+P DTLDL + LNDD+A  V+ HP KF+GLGT+P+Q P L V ELKRLK      GIQIG+H+ D++ D     PV+KTCEDL LS+FVHPWDM  G RY+K+W+PWLVGMP ET  A+ S +MG +  ++P LK+CFAHGGGSFPYT+GRI HGYNV P+LCA  C+Q P SF+G F+ DSLVH+   LD LVKVIG+N+V +GSDYPFPLGEH PG+LI+ S+ S  TK KL  KNA EFL + DP  +
Sbjct:   13 KERYGYGGFVQLQQCQGEQAGCKANMMKDGKLFRVVDSNCWSPTTRLDEMKETGVTTQVLSTVPVMFSYWAEPDDTLDLSRILNDDLAQHVTAHPGKFVGLGTVPMQAPELAVTELKRLKADLNFPGIQIGSHINDWNLDAKELYPVWKTCEDLGLSVFVHPWDMVMGGRYSKYWLPWLVGMPAETATAICSMIMGNVFTQFPGLKVCFAHGGGSFPYTVGRIQHGYNVRPDLCAAECSQDPRSFLGKFWCDSLVHDYDALDLLVKVIGDNRVILGSDYPFPLGEHKPGNLIDTSNLSDDTKQKLKFKNAMEFLNL-DPSQY 333
[Close]
BLAST of 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase vs. TrEMBL
Match: K1QDI1 (2-amino-3-carboxymuconate-6-semialdehyde decarboxylase OS=Crassostrea gigas OX=29159 GN=CGI_10008240 PE=3 SV=1)

HSP 1 Score: 387.882 bits (995), Expect = 2.903e-130
Identity = 178/314 (56.69%), Postives = 228/314 (72.61%), Query Frame = 1 
Query:  130 QTKYGYRGWLKIKHDETTGLASLYKDTGEFFRLIKPNCWDLETRIIEMSQTSVDMQVLSTVPVMFNYWAKPKDTLDLCKFLNDDIANSVSKHPNKFIGLGTIPLQDPLLCVEELKRLKMTKGMHGIQIGTHVADYDFDNAFFDPVFKTCEDLDLSIFVHPWDMPSGKRYNKFWMPWLVGMPNETTIALLSFLMGGILLKYPKLKICFAHGGGSFPYTMGRIDHGYNVCPNLCATACNQCPSSFIGNFYTDSLVHNDQTLDFLVKVIGENKVCMGSDYPFPLGEHNPGSLIEESSFSKKTKDKLLAKNAAEFLGI 1071
            + +YGY GW+++ H +  G A + KD G FFR I  NCW  E RI +M +T V +Q LSTVPVMF+YWAKP DTLDL + LN+DIA +V K+P +F+GLGT+P+Q P L V+EL R K   G HG+QIG+HV D++ D     P+F   E  ++SIFVHPWDM    R  K+W+PWLVGMP+ET  A+   +MGG+L ++PKLK+CFAHGGG+FP+T+GRI+HGYNV P+LCAT C   P  F+G FYTD+LVH+   L  LV VIGE++V MGSDYPFPLGEH+PG LIE   F +  K+KLL  NA EFLG+
Sbjct:   18 KQRYGYGGWVQLHH-KCAGKADMMKD-GNFFRTIDENCWSPEARIRDMDETGVTVQALSTVPVMFSYWAKPADTLDLSQILNNDIAETVKKYPQRFVGLGTLPMQAPELAVKELVRCKQELGFHGVQIGSHVNDWNLDAQELRPIFAAAEKHEMSIFVHPWDMDLSGRMKKYWLPWLVGMPSETATAICCMVMGGVLEEFPKLKVCFAHGGGAFPFTVGRIEHGYNVRPDLCATDCKTGPRQFLGKFYTDALVHDPVALKLLVDVIGEDRVIMGSDYPFPLGEHHPGKLIESMDFQQPLKEKLLVNNACEFLGL 329
[Close]
BLAST of 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase vs. TrEMBL
Match: A0A444SHM2 (2-amino-3-carboxymuconate-6-semialdehyde decarboxylase OS=Armadillidium vulgare OX=13347 GN=Avbf_12195 PE=3 SV=1)

HSP 1 Score: 383.645 bits (984), Expect = 3.217e-129
Identity = 169/287 (58.89%), Postives = 219/287 (76.31%), Query Frame = 1 
Query:  211 GEFFRLIKPNCWDLETRIIEMSQTSVDMQVLSTVPVMFNYWAKPKDTLDLCKFLNDDIANSVSKHPNKFIGLGTIPLQDPLLCVEELKRLKMTKGMHGIQIGTHVADYDFDNAFFDPVFKTCEDLDLSIFVHPWDMPSGKRYNKFWMPWLVGMPNETTIALLSFLMGGILLKYPKLKICFAHGGGSFPYTMGRIDHGYNVCPNLCATACNQCPSSFIGNFYTDSLVHNDQTLDFLVKVIGENKVCMGSDYPFPLGEHNPGSLIEESSFSKKTKDKLLAKNAAEFLGI 1071
            GE FR+I  NCWD   R+ +M  T V +Q LSTVPVMF+YWAKP  TLDL + LND++  +V +HPN+F+GLGT+PLQ P L VEELKRLK      GIQIG+H+ +++ D     P++KTCEDL LS+FVHPWDM  G RY K+W+PWLVGMP+ET +A+ S LMG +L ++PKL++CF HGGG+FPY  GR+ HGYNV P+LCAT C   P S++G F+ DSLVH+++ L FL+K++GE+K+ +GSDYPFPLGEH+PG LIE S  S  TK+KLL KNA +FLG+
Sbjct:    5 GEVFRVIDSNCWDSNDRVRDMDSTGVTIQALSTVPVMFSYWAKPDHTLDLSRILNDNLGETVRRHPNRFVGLGTVPLQAPELAVEELKRLKSDLNFAGIQIGSHINEWNLDAKELHPIWKTCEDLGLSVFVHPWDMQMGGRYQKYWLPWLVGMPSETAVAICSVLMGNVLEQFPKLRLCFGHGGGAFPYIAGRVQHGYNVRPDLCATDCVNSPLSYLGKFWCDSLVHDEEALKFLIKIVGEDKIVLGSDYPFPLGEHHPGMLIETSDLSVTTKEKLLHKNAYDFLGL 291
[Close]
BLAST of 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase vs. TrEMBL
Match: A0A2G8JPL2 (2-amino-3-carboxymuconate-6-semialdehyde decarboxylase OS=Stichopus japonicus OX=307972 GN=BSL78_25483 PE=3 SV=1)

HSP 1 Score: 386.341 bits (991), Expect = 3.601e-129
Identity = 175/315 (55.56%), Postives = 232/315 (73.65%), Query Frame = 1 
Query:  130 QTKYGYRGWLKIKHDETTGLASLYKDTGEFFRLIKPNCWDLETRIIEMSQTSVDMQVLSTVPVMFNYWAKPKDTLDLCKFLNDDIANSVSKHPNKFIGLGTIPLQDPLLCVEELKRLKMTKGMHGIQIGTHVADYDFDNAFFDPVFKTCEDLDLSIFVHPWDMPSGKRYNKFWMPWLVGMPNETTIALLSFLMGGILLKYPKLKICFAHGGGSFPYTMGRIDHGYNVCPNLCATACNQCPSSFIGNFYTDSLVHNDQTLDFLVKVIGENKVCMGSDYPFPLGEHNPGSLIEE-SSFSKKTKDKLLAKNAAEFLGI 1071
            + +YGY GW+++ HD+  G AS+ +D G+ FR+I  NCWD ETRI EM  T V +Q LSTVPVMF+YWAKP+DTLDLC+ LNDD+A +V K+P +F+  GT+P+Q P L V+ELKR++M  G  G+QIG+H+ D++ D     P+F   E+ D ++FVHPWDM    R  K+W+PWLVGMP ET  A+   + GGIL +YPKLK+ FAHGGG+FP+T+GRI+HG+NV P+LCA   +  P  ++G  YTDSLVH+   L++L+K IGEN+V +GSDYPFPLGEH+PG LIE   S S+  KD LLA NA EFLG+
Sbjct:   21 KERYGYGGWIQL-HDKCNGKASMMRD-GKLFRVIDQNCWDPETRIQEMDATGVTVQALSTVPVMFSYWAKPEDTLDLCRILNDDLAQTVKKYPKRFVAFGTLPMQAPDLAVKELKRIRMELGFPGVQIGSHINDWNLDAPELQPIFAAAEEYDCALFVHPWDMQLDGRMKKYWLPWLVGMPGETAQAMCCLIFGGILERYPKLKVMFAHGGGAFPFTIGRIEHGFNVRPDLCAVENDVNPRKYLGKIYTDSLVHDPGALEYLIKTIGENRVSLGSDYPFPLGEHHPGKLIESMDSLSEDVKDALLAGNALEFLGL 333
[Close]
BLAST of 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase vs. Ensembl Cavefish
Match: acmsd (aminocarboxymuconate semialdehyde decarboxylase [Source:NCBI gene;Acc:103024367])

HSP 1 Score: 365.54 bits (937), Expect = 6.919e-125
Identity = 168/315 (53.33%), Postives = 230/315 (73.02%), Query Frame = 1 
Query:  130 QTKYGYRGWLKIKHDETTGLASLYKDTGEFFRLIKPNCWDLETRIIEMSQTSVDMQVLSTVPVMFNYWAKPKDTLDLCKFLNDDIANSVSKHPNKFIGLGTIPLQDPLLCVEELKRLKMTKGMHGIQIGTHVADYDFDNAFFDPVFKTCEDLDLSIFVHPWDMPSGKRYNKFWMPWLVGMPNETTIALLSFLMGGILLKYPKLKICFAHGGGSFPYTMGRIDHGYNVCPNLCATACNQCPSSFIGNFYTDSLVHNDQTLDFLVKVIGENKVCMGSDYPFPLGEHNPGSLIEE-SSFSKKTKDKLLAKNAAEFLGI 1071
            + +YGY G++++ H    G A + KD G+ FR+I+ NCWD E RI +M +  V +Q LSTVPVMF+YWAKP+DTLDLC  LNDD+A +V ++P +F+GLGT+P+Q P L V+E++R     G  G+QIG+HV  +D +     P++   E+L+ +IFVHPWDM + +R  K+W+PWLVGMP+ETTIA+ S + GGI  ++PKL++CFAHGGG+FPYT+GRI+HG+NV P+LCAT     P  ++ +FYTDSLVH+   L  L+ VIG++KV +G+DYPFPLGE  PG+LIE  S F    KD LLA NA EFLG+
Sbjct:   18 KERYGYDGFVQLHH-HCKGEAKMMKD-GKLFRVIQENCWDAEARIRDMDKHGVTVQALSTVPVMFSYWAKPQDTLDLCGILNDDLAATVRRYPKRFVGLGTLPMQAPELAVQEMRRCVKELGFPGVQIGSHVNTWDLNAPELYPIYAAAEELNCAIFVHPWDMKTDERMAKYWLPWLVGMPSETTIAICSMIFGGIFERFPKLRVCFAHGGGAFPYTIGRIEHGFNVRPDLCATDNKINPRKYLRSFYTDSLVHDPLALQLLIDVIGQDKVILGTDYPFPLGELEPGTLIESMSGFDSTLKDNLLAGNALEFLGL 330
[Close]
BLAST of 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase vs. Ensembl Cavefish
Match: acmsd (aminocarboxymuconate semialdehyde decarboxylase [Source:NCBI gene;Acc:103024367])

HSP 1 Score: 365.54 bits (937), Expect = 6.919e-125
Identity = 168/315 (53.33%), Postives = 230/315 (73.02%), Query Frame = 1 
Query:  130 QTKYGYRGWLKIKHDETTGLASLYKDTGEFFRLIKPNCWDLETRIIEMSQTSVDMQVLSTVPVMFNYWAKPKDTLDLCKFLNDDIANSVSKHPNKFIGLGTIPLQDPLLCVEELKRLKMTKGMHGIQIGTHVADYDFDNAFFDPVFKTCEDLDLSIFVHPWDMPSGKRYNKFWMPWLVGMPNETTIALLSFLMGGILLKYPKLKICFAHGGGSFPYTMGRIDHGYNVCPNLCATACNQCPSSFIGNFYTDSLVHNDQTLDFLVKVIGENKVCMGSDYPFPLGEHNPGSLIEE-SSFSKKTKDKLLAKNAAEFLGI 1071
            + +YGY G++++ H    G A + KD G+ FR+I+ NCWD E RI +M +  V +Q LSTVPVMF+YWAKP+DTLDLC  LNDD+A +V ++P +F+GLGT+P+Q P L V+E++R     G  G+QIG+HV  +D +     P++   E+L+ +IFVHPWDM + +R  K+W+PWLVGMP+ETTIA+ S + GGI  ++PKL++CFAHGGG+FPYT+GRI+HG+NV P+LCAT     P  ++ +FYTDSLVH+   L  L+ VIG++KV +G+DYPFPLGE  PG+LIE  S F    KD LLA NA EFLG+
Sbjct:   18 KERYGYDGFVQLHH-HCKGEAKMMKD-GKLFRVIQENCWDAEARIRDMDKHGVTVQALSTVPVMFSYWAKPQDTLDLCGILNDDLAATVRRYPKRFVGLGTLPMQAPELAVQEMRRCVKELGFPGVQIGSHVNTWDLNAPELYPIYAAAEELNCAIFVHPWDMKTDERMAKYWLPWLVGMPSETTIAICSMIFGGIFERFPKLRVCFAHGGGAFPYTIGRIEHGFNVRPDLCATDNKINPRKYLRSFYTDSLVHDPLALQLLIDVIGQDKVILGTDYPFPLGELEPGTLIESMSGFDSTLKDNLLAGNALEFLGL 330
[Close]
BLAST of 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase vs. Ensembl Sea Lamprey
Match: acmsd (aminocarboxymuconate semialdehyde decarboxylase [Source:ZFIN;Acc:ZDB-GENE-070410-103])

HSP 1 Score: 355.14 bits (910), Expect = 1.886e-121
Identity = 162/313 (51.76%), Postives = 218/313 (69.65%), Query Frame = 1 
Query:  136 KYGYRGWLKIKHDETTGLASLYKDTGEFFRLIKPNCWDLETRIIEMSQTSVDMQVLSTVPVMFNYWAKPKDTLDLCKFLNDDIANSVSKHPNKFIGLGTIPLQDPLLCVEELKRLKMTKGMHGIQIGTHVADYDFDNAFFDPVFKTCEDLDLSIFVHPWDMPSGKRYNKFWMPWLVGMPNETTIALLSFLMGGILLKYPKLKICFAHGGGSFPYTMGRIDHGYNVCPNLCATACNQCPSSFIGNFYTDSLVHNDQTLDFLVKVIGENKVCMGSDYPFPLGEHNPGSLIEE-SSFSKKTKDKLLAKNAAEFLGI 1071
            +YGY GW+ ++H  + G A + KD G+ FR+I+ N WD   RI EM Q  V +Q LSTVPVMFNYWA+P+D  DLC+ LNDD+A  V + P +F+GLGT+P+Q   L V+EL+R  +  G  G+QIG+HV   + D+     VF   E+L  ++F+HPWDM +  R  K+W+PWLVGMP ETT A+ S + GG+  ++P+LK+CFAHGGGSFP+T+GRI HG++V P+LCA      P  + G FYTDSLVH+   L  LV V+GE++V +G+DYPFPLG+  PG LIE    FS + KDKLL+ NA EFLG+
Sbjct:   20 RYGYGGWVHLEH-HSKGEAKMVKD-GKVFRVIQENSWDPAVRIREMDQQGVTVQALSTVPVMFNYWARPQDAHDLCRLLNDDLAGVVGRFPRRFVGLGTLPMQSAALAVQELRRCTLELGFPGVQIGSHVNACNLDDPELRAVFAEAEELGCALFIHPWDMETTGRMAKYWLPWLVGMPAETTTAICSMIFGGVFERFPRLKVCFAHGGGSFPFTLGRIQHGFDVRPDLCAVDNPHPPRRYAGRFYTDSLVHDPHALRLLVDVLGEDRVMLGTDYPFPLGDLEPGRLIETMEEFSPQLKDKLLSTNALEFLGV 330
[Close]
BLAST of 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase vs. Ensembl Nematostella
Match: EDO34328 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SPM0])

HSP 1 Score: 316.235 bits (809), Expect = 1.029e-106
Identity = 142/268 (52.99%), Postives = 195/268 (72.76%), Query Frame = 1 
Query:  130 QTKYGYRGWLKIKHDETTGLASLYKDTGEFFRLIKPNCWDLETRIIEMSQTSVDMQVLSTVPVMFNYWAKPKDTLDLCKFLNDDIANSVSKHPNKFIGLGTIPLQDPLLCVEELKRLKMTKGMHGIQIGTHVADYDFDNAFFDPVFKTCEDLDLSIFVHPWDMPSGKRYNKFWMPWLVGMPNETTIALLSFLMGGILLKYPKLKICFAHGGGSFPYTMGRIDHGYNVCPNLCATACNQCPSSFIGNFYTDSLVHNDQTLDFLVKVIGE 933
            + +YGY GW+++ H    G A + KD G+ FR+I+ NCW  E RI +M  T V +Q LSTVPVMF+YWAKPKDTLDLCK LNDD+A +V+K+P +F+GLGT+P+Q P L +EEL+R     G  GIQIG+HV +++ D     P+F   E+L+ +IFVHPWDM    R +K+W+PWLVGMP ET +A+ S + GG+L ++P LK+CFAHGGGSFP+T+GRI+HG+NV P+LCA      P +++G  +TDSLVH+ + L +LV  +GE
Sbjct:   21 KERYGYGGWIQLDH-HCKGKAQMMKD-GKLFRVIEENCWSPEARIKDMDATGVSVQALSTVPVMFSYWAKPKDTLDLCKILNDDLAMTVAKYPKRFVGLGTLPMQAPDLALEELRRCIKELGFPGIQIGSHVNEWNLDAPELQPIFALAEELNAAIFVHPWDMELSGRMSKYWLPWLVGMPGETALAMCSMIFGGVLERFPNLKVCFAHGGGSFPFTIGRIEHGFNVRPDLCAVDNQVNPRNYLGRVFTDSLVHDTKALQYLVDTMGE 286
[Close]
BLAST of 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase vs. Ensembl Medaka
Match: acmsd (aminocarboxymuconate semialdehyde decarboxylase [Source:NCBI gene;Acc:101167833])

HSP 1 Score: 360.533 bits (924), Expect = 6.664e-123
Identity = 167/315 (53.02%), Postives = 226/315 (71.75%), Query Frame = 1 
Query:  130 QTKYGYRGWLKIKHDETTGLASLYKDTGEFFRLIKPNCWDLETRIIEMSQTSVDMQVLSTVPVMFNYWAKPKDTLDLCKFLNDDIANSVSKHPNKFIGLGTIPLQDPLLCVEELKRLKMTKGMHGIQIGTHVADYDFDNAFFDPVFKTCEDLDLSIFVHPWDMPSGKRYNKFWMPWLVGMPNETTIALLSFLMGGILLKYPKLKICFAHGGGSFPYTMGRIDHGYNVCPNLCATACNQCPSSFIGNFYTDSLVHNDQTLDFLVKVIGENKVCMGSDYPFPLGEHNPGSLIEE-SSFSKKTKDKLLAKNAAEFLGI 1071
            + +YGY G++++ H    G A + +D G+ FR+I+ NCWD   RI +M Q  V +Q LSTVPVMF+YWAKP+DTLDLC  LND++A +V  HP +F+GLGT+P+Q P L + E++R     G  G+QIG+H+ ++D +     P +   E+L  SIFVHPWDM +  R  K+W+PWLVGMP+ETT+A+ S + GGI  K+PKLK+CFAHGGGSFP+T+GRI+HG+ V P+LCA      P  ++G+FYTDSLVH+  +L  LV+VIG++KV +G+DYPFPLGE  PGSLIE    F    KDKLLA NA +FLG+
Sbjct:   18 KERYGYEGFVQLHH-HCQGSAKMMRD-GKLFRVIQDNCWDAGVRIRDMDQHGVAVQALSTVPVMFSYWAKPQDTLDLCGLLNDNLAQTVRSHPKRFVGLGTLPMQAPDLAILEMRRCVKELGFPGVQIGSHINNWDLNAPELLPFYAAAEELGCSIFVHPWDMQTDGRMAKYWLPWLVGMPSETTVAICSMIFGGIFEKFPKLKVCFAHGGGSFPFTLGRIEHGHKVRPDLCAIDNKMSPRKYLGSFYTDSLVHDPMSLKLLVEVIGKDKVMLGTDYPFPLGELEPGSLIESMDEFDAPIKDKLLAGNALDFLGL 330
[Close]
BLAST of 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase vs. Ensembl Medaka
Match: acmsd (aminocarboxymuconate semialdehyde decarboxylase [Source:NCBI gene;Acc:101167833])

HSP 1 Score: 351.288 bits (900), Expect = 1.830e-119
Identity = 163/301 (54.15%), Postives = 216/301 (71.76%), Query Frame = 1 
Query:  172 DETTGLASLYKDTGEFFRLIKPNCWDLETRIIEMSQTSVDMQVLSTVPVMFNYWAKPKDTLDLCKFLNDDIANSVSKHPNKFIGLGTIPLQDPLLCVEELKRLKMTKGMHGIQIGTHVADYDFDNAFFDPVFKTCEDLDLSIFVHPWDMPSGKRYNKFWMPWLVGMPNETTIALLSFLMGGILLKYPKLKICFAHGGGSFPYTMGRIDHGYNVCPNLCATACNQCPSSFIGNFYTDSLVHNDQTLDFLVKVIGENKVCMGSDYPFPLGEHNPGSLIEE-SSFSKKTKDKLLAKNAAEFLGI 1071
            D   G A + +D G+ FR+I+ NCWD   RI +M Q  V +Q LSTVPVMF+YWAKP+DTLDLC  LND++A +V  HP +F+GLGT+P+Q P L + E++R     G  G+QIG+H+ ++D +     P +   E+L  SIFVHPWDM +  R  K+W+PWLVGMP+ETT+A+ S + GGI  K+PKLK+CFAHGGGSFP+T+GRI+HG+ V P+LCA      P  ++G+FYTDSLVH+  +L  LV+VIG++KV +G+DYPFPLGE  PGSLIE    F    KDKLLA NA +FLG+
Sbjct:   16 DLKEGSAKMMRD-GKLFRVIQDNCWDAGVRIRDMDQHGVAVQALSTVPVMFSYWAKPQDTLDLCGLLNDNLAQTVRSHPKRFVGLGTLPMQAPDLAILEMRRCVKELGFPGVQIGSHINNWDLNAPELLPFYAAAEELGCSIFVHPWDMQTDGRMAKYWLPWLVGMPSETTVAICSMIFGGIFEKFPKLKVCFAHGGGSFPFTLGRIEHGHKVRPDLCAIDNKMSPRKYLGSFYTDSLVHDPMSLKLLVEVIGKDKVMLGTDYPFPLGELEPGSLIESMDEFDAPIKDKLLAGNALDFLGL 315
[Close]
BLAST of 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase vs. Planmine SMEST
Match: SMESG000077491.1 (SMESG000077491.1)

HSP 1 Score: 662.144 bits (1707), Expect = 0.000e+0
Identity = 318/320 (99.38%), Postives = 319/320 (99.69%), Query Frame = 1 
Query:  130 QTKYGYRGWLKIKHDETTGLASLYKDTGEFFRLIKPNCWDLETRIIEMSQTSVDMQVLSTVPVMFNYWAKPKDTLDLCKFLNDDIANSVSKHPNKFIGLGTIPLQDPLLCVEELKRLKMTKGMHGIQIGTHVADYDFDNAFFDPVFKTCEDLDLSIFVHPWDMPSGKRYNKFWMPWLVGMPNETTIALLSFLMGGILLKYPKLKICFAHGGGSFPYTMGRIDHGYNVCPNLCATACNQCPSSFIGNFYTDSLVHNDQTLDFLVKVIGENKVCMGSDYPFPLGEHNPGSLIEESSFSKKTKDKLLAKNAAEFLGITDPMLF 1089
            + KYGYRGWLKIKHDETTGLASLYKDTGEFFRLIKPNCWDLETRIIEMSQTSVDMQVLSTVPVMFNYWAKPKDTLDLCKFLNDDIANSVSKHPNKFIGLGTIPLQDPLLCVEELKRLKMTKGMHGIQIGTHVADYDFDNAFFDPVFKTCEDLDLSIFVHPWDMPSGKRYNKFWMPWLVGMPNETTIALLSFLMGGILLKYPKLKICFAHGGGSFPYTMGRIDHGYNVCPNLCATACNQCPSSFIGNFYTDSLVHNDQTLDFLVKVIGENKVCMGSDYPFPLGEHNPGSLIEESSFSKKTKDKLLAKNAAEFLGITDPMLF
Sbjct:   18 EKKYGYRGWLKIKHDETTGLASLYKDTGEFFRLIKPNCWDLETRIIEMSQTSVDMQVLSTVPVMFNYWAKPKDTLDLCKFLNDDIANSVSKHPNKFIGLGTIPLQDPLLCVEELKRLKMTKGMHGIQIGTHVADYDFDNAFFDPVFKTCEDLDLSIFVHPWDMPSGKRYNKFWMPWLVGMPNETTIALLSFLMGGILLKYPKLKICFAHGGGSFPYTMGRIDHGYNVCPNLCATACNQCPSSFIGNFYTDSLVHNDQTLDFLVKVIGENKVCMGSDYPFPLGEHNPGSLIEESSFSKKTKDKLLAKNAAEFLGITDPMLF 337
The following BLAST results are available for this feature:
BLAST of 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 2
Match NameE-valueIdentityDescription
ACMSD1.449e-12252.70aminocarboxymuconate semialdehyde decarboxylase [S... [more]
ACMSD1.406e-9453.04aminocarboxymuconate semialdehyde decarboxylase [S... [more]
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BLAST of 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2
Match NameE-valueIdentityDescription
acsd-12.416e-10847.522-amino-3-carboxymuconate-6-semialdehyde decarboxy... [more]
acsd-11.253e-9641.242-amino-3-carboxymuconate-6-semialdehyde decarboxy... [more]
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BLAST of 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
acmsd1.203e-12353.80aminocarboxymuconate semialdehyde decarboxylase [S... [more]
acmsd1.203e-12353.80aminocarboxymuconate semialdehyde decarboxylase [S... [more]
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BLAST of 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
gid48.832e-13055.87GID complex subunit 4 homolog [Source:Xenbase;Acc:... [more]
gid46.199e-12355.12GID complex subunit 4 homolog [Source:Xenbase;Acc:... [more]
gid45.114e-11856.01GID complex subunit 4 homolog [Source:Xenbase;Acc:... [more]
gid49.539e-10854.48GID complex subunit 4 homolog [Source:Xenbase;Acc:... [more]
gid41.197e-10353.05GID complex subunit 4 homolog [Source:Xenbase;Acc:... [more]
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BLAST of 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 1
Match NameE-valueIdentityDescription
Acmsd2.612e-12653.33amino carboxymuconate semialdehyde decarboxylase [... [more]
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BLAST of 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q8R519|ACMSD_MOUSE1.827e-12553.332-amino-3-carboxymuconate-6-semialdehyde decarboxy... [more]
sp|Q8R5M5|ACMSD_RAT2.120e-12453.022-amino-3-carboxymuconate-6-semialdehyde decarboxy... [more]
sp|Q0II68|ACMSD_BOVIN4.724e-12352.702-amino-3-carboxymuconate-6-semialdehyde decarboxy... [more]
sp|Q8TDX5|ACMSD_HUMAN6.957e-12252.702-amino-3-carboxymuconate-6-semialdehyde decarboxy... [more]
sp|Q54LN9|ACMSD_DICDI4.636e-11450.942-amino-3-carboxymuconate-6-semialdehyde decarboxy... [more]
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BLAST of 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A210PRF34.847e-13257.322-amino-3-carboxymuconate-6-semialdehyde decarboxy... [more]
A0A2P2HYE61.098e-13056.832-amino-3-carboxymuconate-6-semialdehyde decarboxy... [more]
K1QDI12.903e-13056.692-amino-3-carboxymuconate-6-semialdehyde decarboxy... [more]
A0A444SHM23.217e-12958.892-amino-3-carboxymuconate-6-semialdehyde decarboxy... [more]
A0A2G8JPL23.601e-12955.562-amino-3-carboxymuconate-6-semialdehyde decarboxy... [more]
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BLAST of 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
acmsd6.919e-12553.33aminocarboxymuconate semialdehyde decarboxylase [S... [more]
acmsd6.919e-12553.33aminocarboxymuconate semialdehyde decarboxylase [S... [more]
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BLAST of 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
acmsd1.886e-12151.76aminocarboxymuconate semialdehyde decarboxylase [S... [more]
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BLAST of 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO343281.029e-10652.99Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 2
Match NameE-valueIdentityDescription
acmsd6.664e-12353.02aminocarboxymuconate semialdehyde decarboxylase [S... [more]
acmsd1.830e-11954.15aminocarboxymuconate semialdehyde decarboxylase [S... [more]
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BLAST of 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000077491.10.000e+099.38SMESG000077491.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30019697 ID=SMED30019697|Name=2-amino-3-carboxymuconate-6-semialdehyde decarboxylase|organism=Schmidtea mediterranea sexual|type=transcript|length=1258bp
ATTAGGAGTGTATTTTAACTATCGTTATCTCAAAAGATGTTAGGGATGCT
TCTTAACCTTCCTTATTCACATAAACTATCGATGATAACATCGAACAGGC
TTTATTGGGTTAAGCTCTTGAAGATATGTCAAACCAAATATGGATATCGC
GGCTGGTTGAAAATTAAGCACGATGAAACAACGGGTTTGGCATCACTTTA
TAAAGACACCGGAGAATTTTTCCGACTAATTAAACCAAATTGTTGGGACC
TTGAAACACGAATAATAGAAATGTCCCAAACATCAGTGGATATGCAAGTT
TTATCAACTGTTCCAGTTATGTTTAATTACTGGGCTAAACCAAAAGATAC
GCTGGATTTATGCAAATTTCTTAATGATGATATTGCAAATTCGGTTTCAA
AGCATCCTAATAAATTCATTGGACTTGGGACAATTCCTTTACAAGATCCT
CTGCTATGTGTAGAAGAACTTAAAAGATTAAAGATGACAAAGGGAATGCA
TGGTATTCAAATCGGAACTCATGTTGCTGATTATGATTTTGATAATGCGT
TCTTTGATCCAGTATTCAAGACTTGTGAAGATTTAGATTTATCAATATTC
GTTCATCCATGGGATATGCCTTCTGGTAAAAGATATAATAAATTTTGGAT
GCCTTGGTTAGTAGGCATGCCTAACGAAACCACAATAGCATTATTATCAT
TTCTCATGGGAGGAATATTATTAAAATATCCCAAATTAAAAATCTGTTTT
GCTCACGGAGGCGGGTCATTTCCATATACAATGGGAAGAATTGATCATGG
ATATAATGTTTGTCCGAATTTATGTGCAACTGCTTGTAATCAATGTCCAT
CTTCATTCATTGGGAATTTTTATACTGACTCATTAGTTCACAACGATCAG
ACATTAGATTTTCTTGTCAAAGTGATTGGAGAAAATAAAGTTTGCATGGG
CAGCGATTATCCTTTTCCACTTGGAGAACATAATCCTGGTTCACTTATTG
AAGAAAGTTCATTTTCAAAGAAAACCAAAGACAAACTTCTCGCGAAAAAT
GCAGCAGAATTTTTGGGAATTACTGATCCAATGTTATTTTGATTTGATTC
AACAAAACAAATTAGATTGTAATTAGATCAGTCCAATTGAATGCTGAACA
AAATTTCATTAATACTTTTCATAGTTTTGAACATTTGATTATATTTTCTT
TTCAAGTTAAACAACTTCCATGTTTCGAATAATTACGTATACTTGATAGT
AACGTGAT
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protein sequence of SMED30019697-orf-1

>SMED30019697-orf-1 ID=SMED30019697-orf-1|Name=SMED30019697-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=352bp
MLGMLLNLPYSHKLSMITSNRLYWVKLLKICQTKYGYRGWLKIKHDETTG
LASLYKDTGEFFRLIKPNCWDLETRIIEMSQTSVDMQVLSTVPVMFNYWA
KPKDTLDLCKFLNDDIANSVSKHPNKFIGLGTIPLQDPLLCVEELKRLKM
TKGMHGIQIGTHVADYDFDNAFFDPVFKTCEDLDLSIFVHPWDMPSGKRY
NKFWMPWLVGMPNETTIALLSFLMGGILLKYPKLKICFAHGGGSFPYTMG
RIDHGYNVCPNLCATACNQCPSSFIGNFYTDSLVHNDQTLDFLVKVIGEN
KVCMGSDYPFPLGEHNPGSLIEESSFSKKTKDKLLAKNAAEFLGITDPML
F*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0001760aminocarboxymuconate-semialdehyde decarboxylase activity
GO:0016829lyase activity
GO:0016787hydrolase activity
GO:0016831carboxy-lyase activity
Vocabulary: cellular component
TermDefinition
GO:0005737cytoplasm
GO:0005829cytosol
Vocabulary: biological process
TermDefinition
GO:1904985negative regulation of quinolinate biosynthetic process
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0002142parenchyma
Vocabulary: INTERPRO
TermDefinition
IPR032465ACMSD
IPR032466Metal_Hydrolase
IPR006680Amidohydro-rel
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR006680Amidohydrolase-relatedPFAMPF04909Amidohydro_2coord: 66..345
e-value: 4.2E-55
score: 187.6
NoneNo IPR availableGENE3DG3DSA:3.20.20.140coord: 23..347
e-value: 2.5E-90
score: 305.0
IPR0324652-amino-3-carboxymuconate-6-semialdehyde decarboxylasePANTHERPTHR212402-AMINO-3-CARBOXYLMUCONATE-6-SEMIALDEHYDE DECARBOXYLASEcoord: 54..344
IPR032466Metal-dependent hydrolaseSUPERFAMILYSSF51556Metallo-dependent hydrolasescoord: 52..346