Serine-protein kinase ATM
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30019647 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 26
Homology
BLAST of Serine-protein kinase ATM vs. Ensembl Human
Match: ATM (ATM serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:795]) HSP 1 Score: 483.026 bits (1242), Expect = 2.411e-136 Identity = 323/954 (33.86%), Postives = 523/954 (54.82%), Query Frame = 3
Query: 5613 AMYDFLYS-RSEHVSEFYRNHVVDSCKISWDQEACFRPLIERATLFGNETSLPTI--LESLIRIANKSNIDQLDSS--IVWA----LIRSNRFARNLEIVNQQLLGISDLAKRCKRHEYIDFIRDMLNLHEVDNSILKCSGESSLFRTIDIFSQKT-ETEETKKSFLQLE--QFIYDSQKHILTC----QQIKR------NHDLFFKLYFKAVSKICA-WNQEYPVHSVSHIRTKILEPAMGVFGKSLKQESDMLS--------TMSTFSYQQYTHINQYMRSSEYENRVKILTESKRDVSYLVDLRGKCPLRKILEKQSEVDWDEL--NNLSQDRERFLLSAAISCSECLQNEDGNDFKIFHLMSMWLSNESNEKLNNIISDVIGKIETHKFLVLMPQLCARLNSE--NNKSFEINLEKLIKRIILDHPFHSIYNLLAIRNANRDXXXXXXXXXXXXXXAND--KMNSRI----SVAYTMVEQLVKESQSDIIRDADILTTAYIHWANVDMSAFKQDIHKKLKFPLNCSLLRIAKQVKLPVPTLSIPIDRSLKYSLDRLPLIVGFDDVYSLQGGINLPKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKVIPMTQTSGIIEWCEDTVPLGDWLANDKTGAHQRYRPQDSTPLQCRKRLQISAEENIKKRIETFKDILTKIQPVLGYFHFEKFPESQRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAFDLGKLMPTQERVPFRLTRDLVHGLGPFGVEGRFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLHSWKLNPQHARVLHTKREADNDCXXXXXXXXXXIEGFDNKSRPGSSQNQMAERVILEMSRKFAGAVDSSYLNCEGHVNYLIQTASNVENLARMFHGWQAYL 8351
++Y+ L S R S FY + + ++ +E C R L +L+ + L I LES+ + ++S + S I W L++ + F+ I+ + + + L ++ + + I+D+L H V+ SIL + +++ IF K + S QLE Q + ++ L Q IK+ ++ KL + ++C W E + + + I LE A+ V G + SD L +++ FS QY I YM+SSE+EN+ +L +K +V L + + + R ++ Q E++ DEL L +DR+RFL A + CL + + +D +F L S+WL N ++N ++ KI T+KFL LM QL AR+ ++ F L LI RI +DHP H+++ +LA+ NANRD L K + + + + K +S++ + A + ++ + ++R + L AYI AN+D + +K K + P + + ++ + VPT+ I +D + +Y L I F + L GG+NLPKI+ C SDG +RRQLVK DDLRQD+VMQQVF + N+LL + + T K R ++I TYKV+P++Q SG++EWC TVP+G++L N++ GAH+RYRP D + QC+K++ +++ +++ E F D+ QPV YF EKF + WF+ R +Y S+A +SIVG+ILGLGDRHVQNIL++ +AEL+HID G+AF+ GK++PT E VPFRLTRD+V G+G GVEG F+ C + ++R+ ++ +LT++EVLL+DPL W +NP A L+ ++ +++ ++ E N S S N++AERV++ + K G + + L+ G VN LIQ A + +NL+R+F GW+A++
Sbjct: 2127 SLYNALQSLRDREFSTFYES--LKYARVKEVEEMCKRSLESVYSLYPTLSRLQAIGELESIGELFSRSVTHRQLSEVYIKWQKHSQLLKDSDFSFQEPIMALRTVILEILMEKEMDNSQRECIKDILTKHLVELSILARTFKNTQLPERAIFQIKQYNSVSCGVSEWQLEEAQVFWAKKEQSLALSILKQMIKKLDASCAANNPSLKLTYTECLRVCGNWLAETCLENPAVIMQTYLEKAVEVAGNYDGESSDELRNGKMKAFLSLARFSDTQYQRIENYMKSSEFENKQALLKRAKEEVGLLREHKIQTN-RYTVKVQRELELDELALRALKEDRKRFLCKAVENYINCLLSGEEHDMWVFRLCSLWLENSGVSEVNGMMKRDGMKIPTYKFLPLMYQLAARMGTKMMGGLGFHEVLNNLISRISMDHPHHTLFIILALANANRDEFLTKPEVARRSRITKNVPKQSSQLDEDRTEAANRIICTIRSRRPQMVRSVEALCDAYIILANLDATQWKTQ-RKGINIPADQPITKLKNLEDVVVPTMEIKVDHTGEYG--NLVTIQSFKAEFRLAGGVNLPKIIDCVGSDGKERRQLVKGRDDLRQDAVMQQVFQMCNTLL-QRNTETRK---------------RKLTICTYKVVPLSQRSGVLEWCTGTVPIGEFLVNNEDGAHKRYRPNDFSAFQCQKKMMEVQKKSFEEKYEVFMDVCQNFQPVFRYFCMEKFLDPAIWFEKRLAYTRSVATSSIVGYILGLGDRHVQNILINEQSAELVHIDLGVAFEQGKILPTPETVPFRLTRDIVDGMGITGVEGVFRRCCEKTMEVMRNSQETLLTIVEVLLYDPLFDWTMNPLKA--LYLQQRPEDETELHPTLNADDQECKRNLSDIDQSFNKVAERVLMRLQEKLKGVEEGTVLSVGGQVNLLIQQAIDPKNLSRLFPGWKAWV 3056
BLAST of Serine-protein kinase ATM vs. Ensembl Human
Match: ATM (ATM serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:795]) HSP 1 Score: 483.026 bits (1242), Expect = 2.411e-136 Identity = 323/954 (33.86%), Postives = 523/954 (54.82%), Query Frame = 3
Query: 5613 AMYDFLYS-RSEHVSEFYRNHVVDSCKISWDQEACFRPLIERATLFGNETSLPTI--LESLIRIANKSNIDQLDSS--IVWA----LIRSNRFARNLEIVNQQLLGISDLAKRCKRHEYIDFIRDMLNLHEVDNSILKCSGESSLFRTIDIFSQKT-ETEETKKSFLQLE--QFIYDSQKHILTC----QQIKR------NHDLFFKLYFKAVSKICA-WNQEYPVHSVSHIRTKILEPAMGVFGKSLKQESDMLS--------TMSTFSYQQYTHINQYMRSSEYENRVKILTESKRDVSYLVDLRGKCPLRKILEKQSEVDWDEL--NNLSQDRERFLLSAAISCSECLQNEDGNDFKIFHLMSMWLSNESNEKLNNIISDVIGKIETHKFLVLMPQLCARLNSE--NNKSFEINLEKLIKRIILDHPFHSIYNLLAIRNANRDXXXXXXXXXXXXXXAND--KMNSRI----SVAYTMVEQLVKESQSDIIRDADILTTAYIHWANVDMSAFKQDIHKKLKFPLNCSLLRIAKQVKLPVPTLSIPIDRSLKYSLDRLPLIVGFDDVYSLQGGINLPKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKVIPMTQTSGIIEWCEDTVPLGDWLANDKTGAHQRYRPQDSTPLQCRKRLQISAEENIKKRIETFKDILTKIQPVLGYFHFEKFPESQRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAFDLGKLMPTQERVPFRLTRDLVHGLGPFGVEGRFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLHSWKLNPQHARVLHTKREADNDCXXXXXXXXXXIEGFDNKSRPGSSQNQMAERVILEMSRKFAGAVDSSYLNCEGHVNYLIQTASNVENLARMFHGWQAYL 8351
++Y+ L S R S FY + + ++ +E C R L +L+ + L I LES+ + ++S + S I W L++ + F+ I+ + + + L ++ + + I+D+L H V+ SIL + +++ IF K + S QLE Q + ++ L Q IK+ ++ KL + ++C W E + + + I LE A+ V G + SD L +++ FS QY I YM+SSE+EN+ +L +K +V L + + + R ++ Q E++ DEL L +DR+RFL A + CL + + +D +F L S+WL N ++N ++ KI T+KFL LM QL AR+ ++ F L LI RI +DHP H+++ +LA+ NANRD L K + + + + K +S++ + A + ++ + ++R + L AYI AN+D + +K K + P + + ++ + VPT+ I +D + +Y L I F + L GG+NLPKI+ C SDG +RRQLVK DDLRQD+VMQQVF + N+LL + + T K R ++I TYKV+P++Q SG++EWC TVP+G++L N++ GAH+RYRP D + QC+K++ +++ +++ E F D+ QPV YF EKF + WF+ R +Y S+A +SIVG+ILGLGDRHVQNIL++ +AEL+HID G+AF+ GK++PT E VPFRLTRD+V G+G GVEG F+ C + ++R+ ++ +LT++EVLL+DPL W +NP A L+ ++ +++ ++ E N S S N++AERV++ + K G + + L+ G VN LIQ A + +NL+R+F GW+A++
Sbjct: 2127 SLYNALQSLRDREFSTFYES--LKYARVKEVEEMCKRSLESVYSLYPTLSRLQAIGELESIGELFSRSVTHRQLSEVYIKWQKHSQLLKDSDFSFQEPIMALRTVILEILMEKEMDNSQRECIKDILTKHLVELSILARTFKNTQLPERAIFQIKQYNSVSCGVSEWQLEEAQVFWAKKEQSLALSILKQMIKKLDASCAANNPSLKLTYTECLRVCGNWLAETCLENPAVIMQTYLEKAVEVAGNYDGESSDELRNGKMKAFLSLARFSDTQYQRIENYMKSSEFENKQALLKRAKEEVGLLREHKIQTN-RYTVKVQRELELDELALRALKEDRKRFLCKAVENYINCLLSGEEHDMWVFRLCSLWLENSGVSEVNGMMKRDGMKIPTYKFLPLMYQLAARMGTKMMGGLGFHEVLNNLISRISMDHPHHTLFIILALANANRDEFLTKPEVARRSRITKNVPKQSSQLDEDRTEAANRIICTIRSRRPQMVRSVEALCDAYIILANLDATQWKTQ-RKGINIPADQPITKLKNLEDVVVPTMEIKVDHTGEYG--NLVTIQSFKAEFRLAGGVNLPKIIDCVGSDGKERRQLVKGRDDLRQDAVMQQVFQMCNTLL-QRNTETRK---------------RKLTICTYKVVPLSQRSGVLEWCTGTVPIGEFLVNNEDGAHKRYRPNDFSAFQCQKKMMEVQKKSFEEKYEVFMDVCQNFQPVFRYFCMEKFLDPAIWFEKRLAYTRSVATSSIVGYILGLGDRHVQNILINEQSAELVHIDLGVAFEQGKILPTPETVPFRLTRDIVDGMGITGVEGVFRRCCEKTMEVMRNSQETLLTIVEVLLYDPLFDWTMNPLKA--LYLQQRPEDETELHPTLNADDQECKRNLSDIDQSFNKVAERVLMRLQEKLKGVEEGTVLSVGGQVNLLIQQAIDPKNLSRLFPGWKAWV 3056
BLAST of Serine-protein kinase ATM vs. Ensembl Human
Match: ATR (ATR serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:882]) HSP 1 Score: 209.92 bits (533), Expect = 3.884e-53 Identity = 154/597 (25.80%), Postives = 271/597 (45.39%), Query Frame = 3
Query: 6639 KLNNIISDVIGKIETHKFLVLMPQLCARLNSENNKSFEINLEKLIKRIILDHPFHSIYNLLAIRNANRDXXXXXXXXXXXXXXANDKMNSRISVAYTMVEQLVKESQSDIIRDADILTTAYIHWANVDMSAFKQDIHKKLKFPLNCSLLRIA--KQVKLPVPTLSIPIDRSL------KYSLDRLP----LIVGFDDVYSLQGGINLPKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKVIPMTQTSGIIEWCEDTV---PLGDWLANDK----TGAHQRYRPQDSTPLQCRKRLQISAEENIKKRIETFKD-ILTKIQPVLGYFHFEKFPESQRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAFDLGKLMPTQERVPFRLTRDLVHGLGPFGVEGRFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLHSWKLNPQHARVLHTKREADNDCXXXXXXXXXXIEGFDNKSRPGSSQNQMAERVILEMSRKFAGAVDSSY------LNCEGHVNYLIQTASNVENLARMFHGWQAYL 8351
K+N +I++ + ++FL QL +R+ +++ F + +E +I ++ L +P +++ + A+ ++ + + +N I + K+S + DA LT + N + + F + L+ A ++ +P+ ++ IP S+ S + P I GFDD+ + + PK + + SDG + K DDLR+D + + S++N L A R + IRTY VIP+ GIIEW +T P+ L +K TG R QC + + ++++ F++ +L + P+ + FP+ W+ +R +Y S A+ S+VG+ILGLGDRH +NIL D T E +H+DF F+ G+ E VPFRLT ++V+G+GP G EG F+ C + L+R Q++ ++++++ LHDPL W P H+K + G N+ A+ +L++ ++ G + + L+ EGHV+YLIQ A++ L +M+ GW Y+
Sbjct: 2057 KINKVITEHTNYLAPYQFLTAFSQLISRICHSHDEVFVVLME-IIAKVFLAYPQQAMWMMTAVSKSS---------YPMRVNRCKEILNKAIHM---------KKSLEKFVGDATRLTDKLLELCNKPVDGSSSTLSMSTHFKMLKKLVEEATFSEILIPLQSVMIPTLPSILGTHANHASHEPFPGHWAYIAGFDDMVEILASLQKPKKISLKGSDGKFYIMMCKPKDDLRKDCRLMEFNSLINKCLRK----------------DAESRRRELHIRTYAVIPLNDECGIIEWVNNTAGLRPILTKLYKEKGVYMTGKELR---------QC----MLPKSAALSEKLKVFREFLLPRHPPIFHEWFLRTFPDPTSWYSSRSAYCRSTAVMSMVGYILGLGDRHGENILFDSLTGECVHVDFNCLFNKGETFEVPEIVPFRLTHNMVNGMGPMGTEGLFRRACEVTMRLMRDQREPLMSVLKTFLHDPLVEWS-KPVKG---HSKAPLNET---------------------GEVVNEKAKTHVLDIEQRLQGVIKTRNRVTGLPLSIEGHVHYLIQEATDENLLCQMYLGWTPYM 2580
BLAST of Serine-protein kinase ATM vs. Ensembl Human
Match: ATR (ATR serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:882]) HSP 1 Score: 209.534 bits (532), Expect = 4.216e-53 Identity = 154/597 (25.80%), Postives = 272/597 (45.56%), Query Frame = 3
Query: 6639 KLNNIISDVIGKIETHKFLVLMPQLCARLNSENNKSFEINLEKLIKRIILDHPFHSIYNLLAIRNANRDXXXXXXXXXXXXXXANDKMNSRISVAYTMVEQLVKESQSDIIRDADILTTAYIHWANVDMSAFKQDIHKKLKFPLNCSLLRIA--KQVKLPVPTLSIPIDRSL------KYSLDRLP----LIVGFDDVYSLQGGINLPKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKVIPMTQTSGIIEWCEDTV---PLGDWLANDK----TGAHQRYRPQDSTPLQCRKRLQISAEENIKKRIETFKD-ILTKIQPVLGYFHFEKFPESQRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAFDLGKLMPTQERVPFRLTRDLVHGLGPFGVEGRFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLHSWKLNPQHARVLHTKREADNDCXXXXXXXXXXIEGFDNKSRPGSSQNQMAERVILEMSRKFAGAVDSSY------LNCEGHVNYLIQTASNVENLARMFHGWQAYL 8351
K+N +I++ + ++FL QL +R+ +++ F + +E +I ++ L +P +++ + A+ ++ + + + +N I + K+S + DA LT + N + + F + L+ A ++ +P+ ++ IP S+ S + P I GFDD+ + + PK + + SDG + K DDLR+D + + S++N L A R + IRTY VIP+ GIIEW +T P+ L +K TG R QC + + ++++ F++ +L + P+ + FP+ W+ +R +Y S A+ S+VG+ILGLGDRH +NIL D T E +H+DF F+ G+ E VPFRLT ++V+G+GP G EG F+ C + L+R Q++ ++++++ LHDPL W P H+K + G N+ A+ +L++ ++ G + + L+ EGHV+YLIQ A++ L +M+ GW Y+
Sbjct: 2121 KINKVITEHTNYLAPYQFLTAFSQLISRICHSHDEVFVVLME-IIAKVFLAYPQQAMWMMTAVSKSSYPMRVNR---------CKEILNKAIHM---------KKSLEKFVGDATRLTDKLLELCNKPVDGSSSTLSMSTHFKMLKKLVEEATFSEILIPLQSVMIPTLPSILGTHANHASHEPFPGHWAYIAGFDDMVEILASLQKPKKISLKGSDGKFYIMMCKPKDDLRKDCRLMEFNSLINKCLRK----------------DAESRRRELHIRTYAVIPLNDECGIIEWVNNTAGLRPILTKLYKEKGVYMTGKELR---------QC----MLPKSAALSEKLKVFREFLLPRHPPIFHEWFLRTFPDPTSWYSSRSAYCRSTAVMSMVGYILGLGDRHGENILFDSLTGECVHVDFNCLFNKGETFEVPEIVPFRLTHNMVNGMGPMGTEGLFRRACEVTMRLMRDQREPLMSVLKTFLHDPLVEWS-KPVKG---HSKAPLNET---------------------GEVVNEKAKTHVLDIEQRLQGVIKTRNRVTGLPLSIEGHVHYLIQEATDENLLCQMYLGWTPYM 2644
BLAST of Serine-protein kinase ATM vs. Ensembl Human
Match: ATR (ATR serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:882]) HSP 1 Score: 190.274 bits (482), Expect = 3.150e-47 Identity = 131/493 (26.57%), Postives = 230/493 (46.65%), Query Frame = 3
Query: 6639 KLNNIISDVIGKIETHKFLVLMPQLCARLNSENNKSFEINLEKLIKRIILDHPFHSIYNLLAIRNANRDXXXXXXXXXXXXXXANDKMNSRISVAYTMVEQLVKESQSDIIRDADILTTAYIHWANVDMSAFKQDIHKKLKFPLNCSLLRIA--KQVKLPVPTLSIPIDRSL------KYSLDRLP----LIVGFDDVYSLQGGINLPKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKVIPMTQTSGIIEWCEDTV---PLGDWLANDK----TGAHQRYRPQDSTPLQCRKRLQISAEENIKKRIETFKD-ILTKIQPVLGYFHFEKFPESQRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAFDLGKLMPTQERVPFRLTRDLVHGLGPFGVEGRFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLHSW 8057
K+N +I++ + ++FL QL +R+ +++ F + +E +I ++ L +P +++ + A+ ++ + + +N I + K+S + DA LT + N + + F + L+ A ++ +P+ ++ IP S+ S + P I GFDD+ + + PK + + SDG + K DDLR+D + + S++N L A R + IRTY VIP+ GIIEW +T P+ L +K TG R QC + + ++++ F++ +L + P+ + FP+ W+ +R +Y S A+ S+VG+ILGLGDRH +NIL D T E +H+DF F+ G+ E VPFRLT ++V+G+GP G EG F+ C + L+R Q++ ++++++ LHDPL W
Sbjct: 1718 KINKVITEHTNYLAPYQFLTAFSQLISRICHSHDEVFVVLME-IIAKVFLAYPQQAMWMMTAVSKSS---------YPMRVNRCKEILNKAIHM---------KKSLEKFVGDATRLTDKLLELCNKPVDGSSSTLSMSTHFKMLKKLVEEATFSEILIPLQSVMIPTLPSILGTHANHASHEPFPGHWAYIAGFDDMVEILASLQKPKKISLKGSDGKFYIMMCKPKDDLRKDCRLMEFNSLINKCLRK----------------DAESRRRELHIRTYAVIPLNDECGIIEWVNNTAGLRPILTKLYKEKGVYMTGKELR---------QC----MLPKSAALSEKLKVFREFLLPRHPPIFHEWFLRTFPDPTSWYSSRSAYCRSTAVMSMVGYILGLGDRHGENILFDSLTGECVHVDFNCLFNKGETFEVPEIVPFRLTHNMVNGMGPMGTEGLFRRACEVTMRLMRDQREPLMSVLKTFLHDPLVEW 2162
BLAST of Serine-protein kinase ATM vs. Ensembl Celegans
Match: atm-1 (Serine/threonine-protein kinase ATM [Source:UniProtKB/Swiss-Prot;Acc:Q9N3Q4]) HSP 1 Score: 169.474 bits (428), Expect = 2.091e-41 Identity = 129/537 (24.02%), Postives = 239/537 (44.51%), Query Frame = 3
Query: 6756 NLEKLIKRIILDHPFHSIYNLLAIRNANRDXXXXXXXXXXXXXXANDKMNSRISVAYTMVEQLVKESQSDIIRDADILTTAYIHWANVDMSAFKQDIHKKLKFPLNCSLLRIAKQVKLPVPTLSIPIDRSLKYSLDRLPLIVGFDDVYSLQGGINLPKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKVIPMTQTSGIIEWCEDTVPLGDWLAN--DKTGAHQRYRPQDSTPLQCRKRLQISAEENIKKRIETFKDILTKIQPVLGYFHFEKFPESQRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAFDLGK-LMPTQERVPFRLTRDLVHGLGPFGVE-GRFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLHSWKLNPQHARVLHTKREADNDCXXXXXXXXXXIEGFDNKSRPGSSQNQMAERVILEMSRKFAGAVDSSYLNCEG-HVNYLIQTASNVENLARMFHGWQAYL 8351
+L +++ +I D+P+H ++ +L + S+++ A+ + +S++ + + + + + D NV + + + ++P + + + K +LP+PT+S I YS L + DV+++ GI+ PKI + SDG K + V DD+RQD +++Q+F V N++L +RTY V+P+ G+IE+C TV L + + + G H+ + ++ + + ++ E+ + R + F +I + PV +F + F +Q W + +Y SLA SIV +I+GLGDRH NIL D +HID G+ + K +P E+VPFR+TRD++ + G+E G+ C ++ L+ +IL + LL + + +++ Q A RP + ++E I + K G D + L++ A++ +NL+RMF GW +L
Sbjct: 1234 HLSQILCHLIYDYPYHVLHTILMYDDEKNASKVKGFLKTIFDARADQRDSSKLKEIVITIREAHQAYREIAMLDVR---------GNVRIQRVEINGKTMYRWPHDLKIFK-CKLRQLPIPTISQKIGCPGDYSTTDLITWKRWKDVFTIADGISTPKIWEIEGSDG-KWYKTVWKKDDVRQDVLVEQMFDVTNNMLEKA------------------------MLRTYNVVPLDTECGVIEFCGGTVSLKEVMCGVTREGGLHREFNSEEVSASKVSSMMRQVQTESTETRRQVFVEICQQYSPVFRHFFYTNFSTAQIWRQKIINYRQSLATWSIVCYIVGLGDRHASNILFDQKLCTFVHIDLGMILEYSKRTLPVPEQVPFRITRDVLDPILIEGIENGQLAEECTQIMEKLKENGKVILGVASALLRETMTNFREAEQAA------------------------------GRP----SYISEMAIGRLREKLRGTDDGVTAQSSNLQIRRLLREATSADNLSRMFCGWMPFL 1701
BLAST of Serine-protein kinase ATM vs. Ensembl Celegans
Match: atm-1 (Serine/threonine-protein kinase ATM [Source:UniProtKB/Swiss-Prot;Acc:Q9N3Q4]) HSP 1 Score: 169.474 bits (428), Expect = 2.464e-41 Identity = 129/537 (24.02%), Postives = 239/537 (44.51%), Query Frame = 3
Query: 6756 NLEKLIKRIILDHPFHSIYNLLAIRNANRDXXXXXXXXXXXXXXANDKMNSRISVAYTMVEQLVKESQSDIIRDADILTTAYIHWANVDMSAFKQDIHKKLKFPLNCSLLRIAKQVKLPVPTLSIPIDRSLKYSLDRLPLIVGFDDVYSLQGGINLPKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKVIPMTQTSGIIEWCEDTVPLGDWLAN--DKTGAHQRYRPQDSTPLQCRKRLQISAEENIKKRIETFKDILTKIQPVLGYFHFEKFPESQRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAFDLGK-LMPTQERVPFRLTRDLVHGLGPFGVE-GRFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLHSWKLNPQHARVLHTKREADNDCXXXXXXXXXXIEGFDNKSRPGSSQNQMAERVILEMSRKFAGAVDSSYLNCEG-HVNYLIQTASNVENLARMFHGWQAYL 8351
+L +++ +I D+P+H ++ +L + S+++ A+ + +S++ + + + + + D NV + + + ++P + + + K +LP+PT+S I YS L + DV+++ GI+ PKI + SDG K + V DD+RQD +++Q+F V N++L +RTY V+P+ G+IE+C TV L + + + G H+ + ++ + + ++ E+ + R + F +I + PV +F + F +Q W + +Y SLA SIV +I+GLGDRH NIL D +HID G+ + K +P E+VPFR+TRD++ + G+E G+ C ++ L+ +IL + LL + + +++ Q A RP + ++E I + K G D + L++ A++ +NL+RMF GW +L
Sbjct: 1911 HLSQILCHLIYDYPYHVLHTILMYDDEKNASKVKGFLKTIFDARADQRDSSKLKEIVITIREAHQAYREIAMLDVR---------GNVRIQRVEINGKTMYRWPHDLKIFK-CKLRQLPIPTISQKIGCPGDYSTTDLITWKRWKDVFTIADGISTPKIWEIEGSDG-KWYKTVWKKDDVRQDVLVEQMFDVTNNMLEKA------------------------MLRTYNVVPLDTECGVIEFCGGTVSLKEVMCGVTREGGLHREFNSEEVSASKVSSMMRQVQTESTETRRQVFVEICQQYSPVFRHFFYTNFSTAQIWRQKIINYRQSLATWSIVCYIVGLGDRHASNILFDQKLCTFVHIDLGMILEYSKRTLPVPEQVPFRITRDVLDPILIEGIENGQLAEECTQIMEKLKENGKVILGVASALLRETMTNFREAEQAA------------------------------GRP----SYISEMAIGRLREKLRGTDDGVTAQSSNLQIRRLLREATSADNLSRMFCGWMPFL 2378
BLAST of Serine-protein kinase ATM vs. Ensembl Celegans
Match: let-363 (Target of rapamycin homolog [Source:UniProtKB/Swiss-Prot;Acc:Q95Q95]) HSP 1 Score: 146.362 bits (368), Expect = 2.427e-34 Identity = 91/287 (31.71%), Postives = 156/287 (54.36%), Query Frame = 3
Query: 7224 PKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKVIPMTQTSGIIEWCEDTVPLGDWLANDKTGAHQRYRPQDSTPLQCR----KRLQISAEE-NIKKRIETFKDILTKIQPV-LGYFHFEKFPESQRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAFDLGKLMPT-QERVPFRLTRDLVHGLGPFGVEGRFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLHSWKL 8063
P+ + + S+GL + L+K ++D RQD + Q+F +VN+LL N R ++I+ Y ++ +++ SG+I W VP D L T + + PL ++L + E + ++++ F+ L+ Q L + + K P S+ WF R +Y S+A S+VG+ILGLGDRH N++LD T +++HIDFG F++ L ERVPFRLTR L++ + G++G + T VL +LR+ ++ +L ++E ++DP+ +W+L
Sbjct: 2340 PRKMVIRGSNGLDYQFLLKGHEDPRQDERVMQLFGLVNTLLANNSETC----------------RRNLTIQRYSIVALSKDSGLIGW----VPNCDTL---HTLVKEYREKKAKIPLSIEHKTLQKLSLETEHLTLMQKLQLFESALSVTQGEDLRHVLWLKSPSSEVWFDRRTNYTRSVACMSMVGYILGLGDRHPSNLMLDRLTGKVVHIDFGDCFEVAMLREKFPERVPFRLTRMLINAMEVTGLDGVYNYTAERVLKMLRTNQESLLAVLEAFVYDPVINWRL 2603
BLAST of Serine-protein kinase ATM vs. Ensembl Celegans
Match: let-363 (Target of rapamycin homolog [Source:UniProtKB/Swiss-Prot;Acc:Q95Q95]) HSP 1 Score: 146.362 bits (368), Expect = 2.428e-34 Identity = 91/287 (31.71%), Postives = 156/287 (54.36%), Query Frame = 3
Query: 7224 PKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKVIPMTQTSGIIEWCEDTVPLGDWLANDKTGAHQRYRPQDSTPLQCR----KRLQISAEE-NIKKRIETFKDILTKIQPV-LGYFHFEKFPESQRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAFDLGKLMPT-QERVPFRLTRDLVHGLGPFGVEGRFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLHSWKL 8063
P+ + + S+GL + L+K ++D RQD + Q+F +VN+LL N R ++I+ Y ++ +++ SG+I W VP D L T + + PL ++L + E + ++++ F+ L+ Q L + + K P S+ WF R +Y S+A S+VG+ILGLGDRH N++LD T +++HIDFG F++ L ERVPFRLTR L++ + G++G + T VL +LR+ ++ +L ++E ++DP+ +W+L
Sbjct: 2343 PRKMVIRGSNGLDYQFLLKGHEDPRQDERVMQLFGLVNTLLANNSETC----------------RRNLTIQRYSIVALSKDSGLIGW----VPNCDTL---HTLVKEYREKKAKIPLSIEHKTLQKLSLETEHLTLMQKLQLFESALSVTQGEDLRHVLWLKSPSSEVWFDRRTNYTRSVACMSMVGYILGLGDRHPSNLMLDRLTGKVVHIDFGDCFEVAMLREKFPERVPFRLTRMLINAMEVTGLDGVYNYTAERVLKMLRTNQESLLAVLEAFVYDPVINWRL 2606
BLAST of Serine-protein kinase ATM vs. Ensembl Celegans
Match: smg-1 (Serine/threonine-protein kinase smg-1 [Source:UniProtKB/Swiss-Prot;Acc:O01510]) HSP 1 Score: 125.946 bits (315), Expect = 3.512e-28 Identity = 89/305 (29.18%), Postives = 139/305 (45.57%), Query Frame = 3
Query: 7224 PKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLG-NKGSITYKANSIKSSDWSAFIYNRMISIRTYKVIPMTQTSGIIEWCEDTVPL----GDWLANDKTGAHQRYRPQDSTPLQCRK--------RLQISAEENIKKRI-------------ETFKDILTKI-QPVLGYFHFEKFPESQRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAFDLGKLMPTQERVPFRLTRDLVHGLGPFGVEGRFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLHSW 8057
PK + SDG + L K +DL D + Q + N +L KG + ++ Y VIP+ SG+I+W E P+ W +K + ++ P R RL A+ I I E F+ + K ++ + + ++ W+ K Y+ SLA+ S+VG +LGLGDRH+ N+L+D+ ++HID+ I FD GK + E VPFRLTR++ H LGP + G F+ +C VL+ LRS ++ L++ + DPL W
Sbjct: 1767 PKKLGFVGSDGKQVAFLFKGREDLHLDERVMQFLRLCNVMLQPGKGKHRQSVAAYQAHH--------------YAVIPLGPRSGLIKWVEGATPMFHIYRKWQMKEKALKQATKKNGETVPEIERPSNMYHNMIRLAF-ADHKIDSSITSDRSKWPAEILEEVFESLTAKTPTDLISRELWMRANDATTWWSVTKRYSRSLAVMSMVGSVLGLGDRHLDNLLVDLKWGHVVHIDYNICFDKGKNLRIPETVPFRLTRNMRHALGPSEMYGTFRESCVHVLSTLRSGHQVLTMLLDAFVFDPLVDW 2056
BLAST of Serine-protein kinase ATM vs. Ensembl Fly
Match: tefu (gene:FBgn0045035 transcript:FBtr0110874) HSP 1 Score: 337.421 bits (864), Expect = 3.242e-92 Identity = 226/699 (32.33%), Postives = 348/699 (49.79%), Query Frame = 3
Query: 6288 KQESDMLSTMSTFSYQQYTHINQYMRSSEYENRVKILTESKRDVSYLVDLRGKCPLRKI---LEKQSEVDWDELNNLSQDRERFL-LSAAISCSECLQNEDGNDFKIFHLMSMWLSNESNEKLNNIISDVIGKIETHKFLVLMPQLCARLNSENNKSFEINLEKLIKRIILDHPFHSIYNLLAIRNANRDXXXXXXXXXXXXXXANDKMNSRISVAYTMVEQLVKE--SQSDIIRDADILTTAYIHWANVDMSAFKQDIHKKLKFPLNCSLLRIAKQVKLPVPTLSIPIDRSLKYSLDRLPLIVGFDDVYSLQGGINLPKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKVIPMTQTSGIIEWCEDTVPLGDWLA-NDKTGAHQRYRPQDSTPLQCRKRLQISAEENIKKRIETFKDILTKIQPVLGYFHFEKFPESQRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAFDLGKLMPTQERVPFRLTRDLVHGLGPFGVEGRFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLHSWKLNPQHARVLHTKREADNDCXXXXXXXXXXIEGFDNKSRPGSSQNQMAERVILEMSRKF----AGAVDSSYLNCEGHVNYLIQTASNVENLARMFHGWQAYL 8351
KQ + +T++ ++ ++Y ++ Y S EY+ +K + E R + V R R I +++ + +D +LN + + +L L+ + C + + I+ ++S+W +N ++++ I D I + ++KF+ QL ARLNS+N S L L+ + DHP+H+ Y L + A+ D + R +A ++ + ++ + + + + L A I +AN + + + ++ + R + PTL +P+ S +YS+ +V + + + GG+N P + C SDG R QLVK DDLRQD+VMQQVF +VN LL S FI R + +RTYKV P++ SGI+EWC ++VP+G +L K GAH RYRP D +CRK + + R +K I I+PV YF EKFP WF+ R +Y NS+A S+VG++LGLGDRH QNIL+D TAE+IHIDFGIAF+ GK+ T E VPFRLTRD V +G G +G F +C +++LR K + T++EVLL+DPL W VL K+ + S N +A+R +L + K AG + S N E V LI A+ NL +F GW +L
Sbjct: 2133 KQRTAAYATIAKYADREYQQLHDYRHSQEYQT-LKDIIEQNRQTAEKVTQRENQDRRVISVQMKRYASLDEQQLNQIEEKLTEYLRLALTNYMAYCRLDSGFSSAAIYRIISLWFTNATSKQCQECIKDEILTVPSYKFICAANQLTARLNSKNT-SLLKGLTDLLVQCGKDHPYHTFYQLYPLVFAHLD--------------GENSNTERSGIARKIIAMICEKNGTAGECSKQLESLLPALITFANEGKTNDNRPVSDSVRNKQFDKVRRWRNLNAVHCPTLELPVMPSKEYSIIS---VVKWTNETTQCGGLNAPVKIMCVCSDGKIRAQLVKGKDDLRQDAVMQQVFGIVNELLNQD---------------SEFI-ERKLKLRTYKVTPLSMRSGILEWCTNSVPVGHYLVVEGKGGAHARYRPNDWNNNKCRKLSSDHLKSPKETRYAIYKKICENIKPVFHYFLLEKFPIPGVWFERRLAYTNSVATTSMVGYVLGLGDRHTQNILVDQQTAEVIHIDFGIAFEQGKIQTTPETVPFRLTRDFVAPMGICGTKGVFAKSCEATMHILRRYKSVFTTILEVLLYDPLFIWG-------VLKKKQSP--------------------QQSGEESVNLVAQRALLLVQNKLDGREAGTMGDS--NVEAQVERLINEATLPSNLCMLFPGWDPHL 2767
BLAST of Serine-protein kinase ATM vs. Ensembl Fly
Match: mei-41 (gene:FBgn0004367 transcript:FBtr0074271) HSP 1 Score: 171.014 bits (432), Expect = 1.122e-41 Identity = 150/606 (24.75%), Postives = 271/606 (44.72%), Query Frame = 3
Query: 6603 LMSMWL-------SNESNEKLNNIISDVIGKIETHKFLVLMPQLCARLNSENNKSFEINLEKLIKRIILDHPFHSIYNLLA-IRNANRDXXXXXXXXXXXXXXANDKMNSRISVAYTMVEQLVKESQSDIIRDADILTTAYIHWANVDMSAFKQDIHKKLKFP-LNCSLLRIAKQVKLPVPTLS---------IPIDRSLKYSLDRLPL----IVGFDDVYSLQGGINLPKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKVIPMTQTSGIIEWCEDTVPLGDWLANDKTGAHQRYRPQDSTPLQCRKRLQISAEENIKKRIETF-KDILTKIQPVLGYFHFEKFPESQRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAFDLGKLMPTQERVPFRLTRDLVHGLGPFGVEGRFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLHSWKLNPQHARVLHTKREADNDCXXXXXXXXXXIEGFDNKSRPGSSQNQMAERVILEMSRKFAGAVDSSYLNCEGHVNYLIQTASNVENLARMFHGWQAYL 8351
L+S+WL + E +K+N+++++ + T F + Q+ +RL N F + L +I +++ +P S++ LL ++A L + N + ++ E+L+ + ++ D +S + K K P + LL K ++ +P S +P ++S +++ P I GF + + PK + + SDG LVK DDLR+D+ + + +V L A R + IRTY V+P + G++EW + L + + QR + LQ L + E+I+++ E F K ++ PV + ++F W++AR +Y ++A+ S+VG+ILGLGDRH +NIL + +H+DF F+ G+L+P E VPFRLT +++ +GP GVEG F+ C L LL+ + +++++ ++D + Q T++ A ++ ++A+R+ + R+ A ++ L+ EG VN+LI A+ V+NLA M+ GW A+L
Sbjct: 1983 LISLWLDTTESSTNTEQVKKMNDLLTNCCTALPTAVFYTVYSQMLSRLCHPVNDVFTV-LRNVIIKLVEAYPQQSLWMLLPHFKSAKAHRIKRCKLVLTDSRLQNSTFQKLLQDFNSLTERLMDLTNKEVTLDR-----------TYKLSDLDTRLSKLCKQPEFSQILLPFEKYMQPTLPLNSDSNSSEGSHLPANQS---TVNWFPYQQIYISGFQESVLILRSAAKPKKLTIRCSDGKDYDVLVKPKDDLRRDARLMEFNGLVKRYLHQ----------------DAPARQRRLHIRTYAVLPFNEECGLVEWLPN---LASYRSICMNLYAQRRLVMSTRQLQ---SLAVPLHESIERKREVFTKQLVPAHPPVFQEWLRQRFATPHSWYEARNTYIRTVAVMSMVGYILGLGDRHGENILFAEGNGDAVHVDFNCLFNQGELLPYPEVVPFRLTHNMIVAMGPLGVEGSFRKCCEITLRLLKQESKTLMSILRPFVYD------VGAQ------TRKGAAT-------------------AKITKDVQRIADRLQGHVKRQQANSIP---LSTEGQVNFLINEATKVDNLASMYIGWGAFL 2517
BLAST of Serine-protein kinase ATM vs. Ensembl Fly
Match: Tor (gene:FBgn0021796 transcript:FBtr0080422) HSP 1 Score: 162.54 bits (410), Expect = 3.837e-39 Identity = 131/464 (28.23%), Postives = 215/464 (46.34%), Query Frame = 3
Query: 7056 LKFPLNCSLLRIAKQVKLPVPTLSIPIDRSLKYSLDRLPLIVGFDDVYSLQGGINLPKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKVIPMTQTSGIIEWCEDTVPLGDWLANDKTGAHQRYRPQDSTPLQCRKRLQISAEEN-----IKKRIETFKDILTKIQPV-LGYFHFEKFPESQRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAFDLGKLMPT-QERVPFRLTRDLVHGLGPFGVEGRFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLHSWKLNPQHARVLHTKREADNDCXXXXXXXXXXIEGFDN-------------KSRP--------------GSSQNQMAERVILEMSRKFAGA--VDSSYLNCEGHVNYLIQTASNVENLARMFHGW 8339
L+ P L K ++L VP P ++ S+ + L V + S Q P+ + + S+G L+K ++DLRQD + Q+FS+VN+LL + + R ++I+ Y VIP++ SG+I W VP D L + YR + PL R ++ + + +++E F+ L + Q L + K P S+ WF+ R +Y SLA+ S+VG+ILGLGDRH N++LD + +++HIDFG F++ E++PFRLTR L+ + G+EG ++ TC V+ +LR KD ++ ++E ++DPL +W R+L ++ ++ + G + KS+P N A +VI + K G +N + V LIQ A+N ENL + + GW
Sbjct: 2042 LELPYVSPKLMTCKDLELAVPGSYNPGQELIRISIIKTNLQV----ITSKQR----PRKLCIRGSNGKDYMYLLKGHEDLRQDERVMQLFSLVNTLLLDDPDT----------------FRRNLAIQRYAVIPLSTNSGLIGW----VPHCDTLHT----LIRDYRDKKKVPLNQEHRTMLNFAPDYDHLTLMQKVEVFEHALGQTQGDDLAKLLWLKSPSSELWFERRNNYTRSLAVMSMVGYILGLGDRHPSNLMLDRMSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLIKAMEVTGIEGTYRRTCESVMLVLRRNKDSLMAVLEAFVYDPLLNW-------RLLDVDKKGNDAVAGAGAPGGRGGSGMQDSLSNSVEDSLPMAKSKPYDPTLQQGGLHNNVADETNSKASQVIKRVKCKLTGTDFQTEKSVNEQSQVELLIQQATNNENLCQCYIGW 2466
BLAST of Serine-protein kinase ATM vs. Ensembl Fly
Match: Tor (gene:FBgn0021796 transcript:FBtr0336615) HSP 1 Score: 162.54 bits (410), Expect = 3.870e-39 Identity = 131/464 (28.23%), Postives = 215/464 (46.34%), Query Frame = 3
Query: 7056 LKFPLNCSLLRIAKQVKLPVPTLSIPIDRSLKYSLDRLPLIVGFDDVYSLQGGINLPKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKVIPMTQTSGIIEWCEDTVPLGDWLANDKTGAHQRYRPQDSTPLQCRKRLQISAEEN-----IKKRIETFKDILTKIQPV-LGYFHFEKFPESQRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAFDLGKLMPT-QERVPFRLTRDLVHGLGPFGVEGRFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLHSWKLNPQHARVLHTKREADNDCXXXXXXXXXXIEGFDN-------------KSRP--------------GSSQNQMAERVILEMSRKFAGA--VDSSYLNCEGHVNYLIQTASNVENLARMFHGW 8339
L+ P L K ++L VP P ++ S+ + L V + S Q P+ + + S+G L+K ++DLRQD + Q+FS+VN+LL + + R ++I+ Y VIP++ SG+I W VP D L + YR + PL R ++ + + +++E F+ L + Q L + K P S+ WF+ R +Y SLA+ S+VG+ILGLGDRH N++LD + +++HIDFG F++ E++PFRLTR L+ + G+EG ++ TC V+ +LR KD ++ ++E ++DPL +W R+L ++ ++ + G + KS+P N A +VI + K G +N + V LIQ A+N ENL + + GW
Sbjct: 2043 LELPYVSPKLMTCKDLELAVPGSYNPGQELIRISIIKTNLQV----ITSKQR----PRKLCIRGSNGKDYMYLLKGHEDLRQDERVMQLFSLVNTLLLDDPDT----------------FRRNLAIQRYAVIPLSTNSGLIGW----VPHCDTLHT----LIRDYRDKKKVPLNQEHRTMLNFAPDYDHLTLMQKVEVFEHALGQTQGDDLAKLLWLKSPSSELWFERRNNYTRSLAVMSMVGYILGLGDRHPSNLMLDRMSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLIKAMEVTGIEGTYRRTCESVMLVLRRNKDSLMAVLEAFVYDPLLNW-------RLLDVDKKGNDAVAGAGAPGGRGGSGMQDSLSNSVEDSLPMAKSKPYDPTLQQGGLHNNVADETNSKASQVIKRVKCKLTGTDFQTEKSVNEQSQVELLIQQATNNENLCQCYIGW 2467
BLAST of Serine-protein kinase ATM vs. Ensembl Fly
Match: nonC (gene:FBgn0263968 transcript:FBtr0070972) HSP 1 Score: 125.561 bits (314), Expect = 6.910e-28 Identity = 82/311 (26.37%), Postives = 153/311 (49.20%), Query Frame = 3
Query: 7224 PKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNK----GSITYKANSIKSSDWSAFIYNRMISIRTYKVIPMTQTSGIIEWCEDTVPLGDWLANDKTGAHQRYR-------------PQDST--------PLQCRKRLQISAEEN---IKKRIETFKDILTKIQP--VLGYFHFEKFPESQRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAFDLGKLMPTQERVPFRLTRDLVHGLGPFGVEGRFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLHSWKLN 8066
PK V S+G + L K +DL D + Q S+ N+++ + G+ Y+A+ Y VIP+ SG+I W + P+ A K +R + P+ T PL + +Q+S I ++ D L++ P +L + + + W ++ + + +++ S++G+++GLGDRH+ N+L+++ + +++HID+ + F+ G+ + E+VPFRLT++LV +G G+EG F+ C VL ++R +++ +LTL+E ++DPL W N
Sbjct: 1910 PKKVAFYGSNGQRYTFLFKGMEDLHLDERIMQFLSISNAIMACRSDAPGNGCYRAHH-------------------YSVIPLGPQSGLISWVDGVTPV---FALYKKWQQRRSQVAGNAGAGAVANVPRRFTDLFYNKLSPLLAKHNMQVSDPRRQWPISVLLQVL-DELSQETPNDLLARELWCQAGNAAEWRQSVRRFVRCMSVMSMIGYVIGLGDRHLDNVLINLGSGDIVHIDYNVCFEKGRTLRIPEKVPFRLTQNLVQAMGITGIEGPFRLGCEYVLKVMRKERETLLTLLEAFVYDPLVDWTTN 2197
BLAST of Serine-protein kinase ATM vs. Ensembl Zebrafish
Match: atm (ATM serine/threonine kinase [Source:ZFIN;Acc:ZDB-GENE-040809-1]) HSP 1 Score: 470.315 bits (1209), Expect = 3.262e-133 Identity = 272/747 (36.41%), Postives = 433/747 (57.97%), Query Frame = 3
Query: 6189 KIC-AWNQEYPVHSVSHIRTKILEPAM--------GVFGKSLKQESDMLSTMSTFSYQQYTHINQYMRSSEYENRVKILTESKRDVSYLVDLRGKCPLRKI--------LEKQSEVDWDELNNLSQDRERFLLSAAISCSECLQNEDGNDFKIFHLMSMWLSNESNEKLNNIISDVIGKIETHKFLVLMPQLCARLNSENNKS-------FEINLEKLIKRIILDHPFHSIYNLLAIRNANRDXXXXXXXXXXXXXXANDKMN-SRISVAYTMVEQLVKESQSDIIRDADILTTAYIHWANVDMSAFKQDIHKKLKFPLNCSLLRIAKQVKLPVPTLSIPIDRSLKYSLDRLPLIVGFDDVYSLQGGINLPKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKVIPMTQTSGIIEWCEDTVPLGDWLANDKTGAHQRYRPQDSTPLQCRKRLQISAEENIKKRIETFKDILTKIQPVLGYFHFEKFPESQRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAFDLGKLMPTQERVPFRLTRDLVHGLGPFGVEGRFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLHSWKLNPQHARVLHTKRE-ADNDCXXXXXXXXXXIEGFDNKSRPGSSQNQMAERVILEMSRKFAGAVDSSYLNCEGHVNYLIQTASNVENLARMFHGWQAYL 8351
++C +W E + S + I LE A+ G+ K Q++ +++ FS QY I YM+SSE+EN+ +L ++K +V + + RK+ ++++ E+D L NL DR RFLL A + ECL+ + +D +F L S+WL N + +N+ + + KI ++KFL LM QL AR+ ++ + S F L +LI + +DHP H+++ +LA+ NAN+D +S+S KS ++ R VA +++ +V++ ++ +++D ++L AYI A +D S K + K + P L++I + +PT+ I +D S +Y + + + F + L GG+NLPKI+ C+ SDG+ RRQLVK DDLRQD+VMQQVF + ++LL +A R ++IR YKV+P +Q SG++EWC TVP+G++L + + GAH+R+RPQD + CRK++ + +++ F ++ +PV YF E+F + W + R +Y S+A +SIVG+I+GLGDRH+QNIL+D T+EL+HID G+AF+ GK++PT E VPFRL+RD+V G+G GVEG F+ C + ++RS ++ +LT++EVLL+DPL W +NP A L E A+ + IE K+ S N++AERV+L + K G D + L+ G VN LIQ A + +NL+R+F GWQA++
Sbjct: 1612 RLCGSWLAESCLESPAVILENYLERAVEVIEEHCGGLKSKLQSQKTQAYFSLARFSDAQYQGIENYMKSSEFENKHALLEKAKEEVDLMRE-------RKVNNNRYTVKVQRELELDVKALANLQADRNRFLLKAVENYIECLELGEEHDTWVFRLASLWLENADVKAVNDKMKSGVKKIPSYKFLPLMYQLAARMGTKVSSSMASQDVGFHHVLNELICQSSVDHPHHTLFIILALVNANKDDSFSRSRSSKSSARQPSPLDLERAEVARKIID-VVRKKRAKMVKDIEMLCNAYITLAYMDASRHKTE-KKAIPIPAEQPLMQIKDLEDVIIPTMDIKVDPSGRY--EDVVTVRSFKRHFHLAGGVNLPKIIDCEGSDGISRRQLVKGQDDLRQDAVMQQVFHMCSTLLQR----------------NAETRKRKLNIRRYKVVPFSQRSGVLEWCSGTVPIGEFLVDPQKGAHKRFRPQDWANMLCRKKMMEAQRMEFNDKLQAFTEVCQNFRPVFRYFCMERFLDPAIWLERRLAYTRSVATSSIVGYIVGLGDRHIQNILIDEQTSELVHIDLGVAFEQGKILPTPETVPFRLSRDIVDGMGITGVEGVFRRCCEKTMEVMRSSQEALLTIVEVLLYDPLFDWTMNPLKAFYLQQHDEQAELNATLNPTPGGDEIETH-RKASDSQSFNKVAERVLLRLQEKLKGVEDGTVLSVGGQVNLLIQQAMDPKNLSRLFPGWQAWV 2330
BLAST of Serine-protein kinase ATM vs. Ensembl Zebrafish
Match: atm (ATM serine/threonine kinase [Source:ZFIN;Acc:ZDB-GENE-040809-1]) HSP 1 Score: 471.085 bits (1211), Expect = 7.599e-133 Identity = 272/747 (36.41%), Postives = 433/747 (57.97%), Query Frame = 3
Query: 6189 KIC-AWNQEYPVHSVSHIRTKILEPAM--------GVFGKSLKQESDMLSTMSTFSYQQYTHINQYMRSSEYENRVKILTESKRDVSYLVDLRGKCPLRKI--------LEKQSEVDWDELNNLSQDRERFLLSAAISCSECLQNEDGNDFKIFHLMSMWLSNESNEKLNNIISDVIGKIETHKFLVLMPQLCARLNSENNKS-------FEINLEKLIKRIILDHPFHSIYNLLAIRNANRDXXXXXXXXXXXXXXANDKMN-SRISVAYTMVEQLVKESQSDIIRDADILTTAYIHWANVDMSAFKQDIHKKLKFPLNCSLLRIAKQVKLPVPTLSIPIDRSLKYSLDRLPLIVGFDDVYSLQGGINLPKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKVIPMTQTSGIIEWCEDTVPLGDWLANDKTGAHQRYRPQDSTPLQCRKRLQISAEENIKKRIETFKDILTKIQPVLGYFHFEKFPESQRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAFDLGKLMPTQERVPFRLTRDLVHGLGPFGVEGRFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLHSWKLNPQHARVLHTKRE-ADNDCXXXXXXXXXXIEGFDNKSRPGSSQNQMAERVILEMSRKFAGAVDSSYLNCEGHVNYLIQTASNVENLARMFHGWQAYL 8351
++C +W E + S + I LE A+ G+ K Q++ +++ FS QY I YM+SSE+EN+ +L ++K +V + + RK+ ++++ E+D L NL DR RFLL A + ECL+ + +D +F L S+WL N + +N+ + + KI ++KFL LM QL AR+ ++ + S F L +LI + +DHP H+++ +LA+ NAN+D +S+S KS ++ R VA +++ +V++ ++ +++D ++L AYI A +D S K + K + P L++I + +PT+ I +D S +Y + + + F + L GG+NLPKI+ C+ SDG+ RRQLVK DDLRQD+VMQQVF + ++LL +A R ++IR YKV+P +Q SG++EWC TVP+G++L + + GAH+R+RPQD + CRK++ + +++ F ++ +PV YF E+F + W + R +Y S+A +SIVG+I+GLGDRH+QNIL+D T+EL+HID G+AF+ GK++PT E VPFRL+RD+V G+G GVEG F+ C + ++RS ++ +LT++EVLL+DPL W +NP A L E A+ + IE K+ S N++AERV+L + K G D + L+ G VN LIQ A + +NL+R+F GWQA++
Sbjct: 2373 RLCGSWLAESCLESPAVILENYLERAVEVIEEHCGGLKSKLQSQKTQAYFSLARFSDAQYQGIENYMKSSEFENKHALLEKAKEEVDLMRE-------RKVNNNRYTVKVQRELELDVKALANLQADRNRFLLKAVENYIECLELGEEHDTWVFRLASLWLENADVKAVNDKMKSGVKKIPSYKFLPLMYQLAARMGTKVSSSMASQDVGFHHVLNELICQSSVDHPHHTLFIILALVNANKDDSFSRSRSSKSSARQPSPLDLERAEVARKIID-VVRKKRAKMVKDIEMLCNAYITLAYMDASRHKTE-KKAIPIPAEQPLMQIKDLEDVIIPTMDIKVDPSGRY--EDVVTVRSFKRHFHLAGGVNLPKIIDCEGSDGISRRQLVKGQDDLRQDAVMQQVFHMCSTLLQR----------------NAETRKRKLNIRRYKVVPFSQRSGVLEWCSGTVPIGEFLVDPQKGAHKRFRPQDWANMLCRKKMMEAQRMEFNDKLQAFTEVCQNFRPVFRYFCMERFLDPAIWLERRLAYTRSVATSSIVGYIVGLGDRHIQNILIDEQTSELVHIDLGVAFEQGKILPTPETVPFRLSRDIVDGMGITGVEGVFRRCCEKTMEVMRSSQEALLTIVEVLLYDPLFDWTMNPLKAFYLQQHDEQAELNATLNPTPGGDEIETH-RKASDSQSFNKVAERVLLRLQEKLKGVEDGTVLSVGGQVNLLIQQAMDPKNLSRLFPGWQAWV 3091
BLAST of Serine-protein kinase ATM vs. Ensembl Zebrafish
Match: atr (ATR serine/threonine kinase [Source:ZFIN;Acc:ZDB-GENE-070912-458]) HSP 1 Score: 216.468 bits (550), Expect = 2.052e-55 Identity = 158/591 (26.73%), Postives = 273/591 (46.19%), Query Frame = 3
Query: 6639 KLNNIISDVIGKIETHKFLVLMPQLCARLNSENNKSFEINLEKLIKRIILDHPFHSIYNLLAIRNANRDXXXXXXXXXXXXXXANDKMNSRISVAYTMVEQLVKESQSDIIRDADILTTAYIHWANVDMSAFKQDIHKKLKFPLNCSLLR--IAKQVKLPVPTLSIPIDRSLKYS---LDRLP----LIVGFDDVYSLQGGINLPKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKVIPMTQTSGIIEWCEDTVPLGDWLAN--DKTGAHQRYRPQDSTPLQCRKRLQISAEENIKKRIETFKDIL-TKIQPVLGYFHFEKFPESQRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAFDLGKLMPTQERVPFRLTRDLVHGLGPFGVEGRFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLHSWKLNPQHARVLHTKREADNDCXXXXXXXXXXIEGFDNK--SRPGSSQNQMAERVILEMSRKFAGAVDSSY------LNCEGHVNYLIQTASNVENLARMFHGWQAYL 8351
K+N++ISD + ++FL QL +R+ +N+ F + +E ++ ++ L +P +++ + A+ ++ + +MN + + + +S I DA+ LT + N + + + F + L+ Q+ +P+ ++ IP S + D P + GFDD + + PK + + SDG + K DDLR+D + + ++N S+ A S + R + IRTY VIP+ + GIIEW T L L + G + T L K+L + +++++ KD+L + PV + FP+ W+ +R +Y S A+ S+VG+ILGLGDRH +NIL D T E +H+DF F+ G+ E VPFRLT+++VH +GP G EG F+ C +L L+R Q++ ++++++ LHDPL W K ++GF + G N+ A+ +L++ ++ G + + L+ EGHV+YLIQ A++ L M+ GW YL
Sbjct: 2115 KINSVISDHTSNLSPYQFLTAFSQLISRICHSSNEVFAVLME-IVAKVFLAYPQQAMWMMTAVSKSSYPT----------------RMNRCKEILKKAIS--LNDSFMKFIGDANRLTDKLLELGNKPVDGNSSTLSMSVHFKMLKKLVEEPTFSQILIPLQSVLIPTLPSTGGANPKHDAFPGHWVYLSGFDDTVEILASLQKPKKISLKGSDGKFYTMMCKPKDDLRKDCRLMEFNCLINK------SLRKDAESRR----------RDLRIRTYAVIPLNEECGIIEWVNKTAGLRHILTKLYKEKGIYV-----SGTEL---KKLILPKTAPFQEKLKLHKDVLCARHPPVFHEWFLRTFPDPTSWYNSRSAYCRSTAVMSMVGYILGLGDRHGENILFDSFTGECVHVDFNCLFNKGETFDVPEVVPFRLTQNMVHAMGPMGTEGLFRQACEVILRLMRDQREPLMSVLKTFLHDPLVEWS---------------------------KPVKGFSKTQVNESGEILNEKAKTHVLDIEQRLQGVIKNRNKVMGLPLSIEGHVHYLIQEATDDNLLCMMYLGWGPYL 2635
BLAST of Serine-protein kinase ATM vs. Ensembl Zebrafish
Match: AL844179.1 (pep chromosome:GRCz11:CHR_ALT_CTG8_1_27:46082265:46126761:-1 gene:ENSDARG00000112020.1 transcript:ENSDART00000184694.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:AL844179.1) HSP 1 Score: 154.066 bits (388), Expect = 2.328e-37 Identity = 122/414 (29.47%), Postives = 202/414 (48.79%), Query Frame = 3
Query: 7224 PKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKVIPMTQTSGIIEWCEDTVPLGDWLANDKTGAHQRYRPQDSTPLQCRKRLQISAEENIKKRIETFKDILTKIQPVLGYFH--------------FEKFPESQRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAFDLGKLMPT-QERVPFRLTRDLVHGLGPFGVEGRFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLHSWKLNPQHARVLHTKREADNDCXXXXXXXXXXIEGFD----NKSRPGSSQ------------------NQMAERVILEMSRKFAGAVDSSY---LNCEGHVNYLIQTASNVENLARMFHGWQA 8345
P+ + S+G + L+K ++DLRQD + Q+F +VN+LL N + K +SI+ Y VIP++ SG+I W VP D L + YR +K++ ++ E I R+ D LT ++ V + H + K P S+ WF R +Y SLA+ S+VG+ILGLGDRH N++LD + +++HIDFG F++ E++PFRLTR L + + G++G ++ TC V+ +LR +D ++ ++E ++DPL +W+L + + KR + T+ S + +EG D +PG++ N+ A ++I + K G D S+ L+ V LI+ A++ ENL ++F W A
Sbjct: 357 PRKLTIMGSNGHEFMFLLKGHEDLRQDERVMQLFGLVNTLLANDPASLRKN----------------LSIQRYAVIPLSTNSGLIGW----VPHCDTLH----ALIRDYRE--------KKKILLNIEHRIMLRMAPDYDHLTLMEKVEVFEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRITCHTVMEVLREHRDSVMAVLEAFVYDPLLNWRLMDTNTK--GNKRSRTRTDSYTAGQSVEAMEGIDLGETTHKKPGTTVPESIHSFIGDGLVQPEALNKKAIQIINRVRDKLTGR-DFSHDETLDVPTQVELLIKQATSHENLCQLF-CWSA 734
BLAST of Serine-protein kinase ATM vs. Ensembl Zebrafish
Match: mtor (mechanistic target of rapamycin kinase [Source:ZFIN;Acc:ZDB-GENE-030131-2974]) HSP 1 Score: 155.992 bits (393), Expect = 4.493e-37 Identity = 121/412 (29.37%), Postives = 201/412 (48.79%), Query Frame = 3
Query: 7224 PKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKVIPMTQTSGIIEWCEDTVPLGDWLANDKTGAHQRYRPQDSTPLQCRKRLQISAEENIKKRIETFKDILTKIQPVLGYFH--------------FEKFPESQRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAFDLGKLMPT-QERVPFRLTRDLVHGLGPFGVEGRFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLHSWKLNPQHARVLHTKREADNDCXXXXXXXXXXIEGFD----NKSRPGSS------------------QNQMAERVILEMSRKFAGAVDSSY---LNCEGHVNYLIQTASNVENLARMFHGW 8339
P+ + S+G + L+K ++DLRQD + Q+F +VN+LL N + K +SI+ Y VIP++ SG+I W VP D L + YR +K++ ++ E I R+ D LT ++ V + H + K P S+ WF R +Y SLA+ S+VG+ILGLGDRH N++LD + +++HIDFG F++ E++PFRLTR L + + G++G ++ TC V+ +LR +D ++ ++E ++DPL +W+L + + KR + T+ S + +EG D +PG++ N+ A ++I + K G D S+ L+ V LI+ A++ ENL + + GW
Sbjct: 2135 PRKLTIMGSNGHEFMFLLKGHEDLRQDERVMQLFGLVNTLLANDPASLRKN----------------LSIQRYAVIPLSTNSGLIGW----VPHCDTLH----ALIRDYRE--------KKKILLNIEHRIMLRMAPDYDHLTLMEKVEVFEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRITCHTVMEVLREHRDSVMAVLEAFVYDPLLNWRLMDTNTK--GNKRSRTRTDSYTAGQSVEAMEGIDLGETTHKKPGTTVPESIHSFIGDGLVQPEALNKKAIQIINRVRDKLTGR-DFSHDETLDVPTQVELLIKQATSHENLCQCYIGW 2511
BLAST of Serine-protein kinase ATM vs. Ensembl Xenopus
Match: ATM (ATM serine/threonine kinase [Source:NCBI gene;Acc:100490767]) HSP 1 Score: 488.034 bits (1255), Expect = 5.704e-138 Identity = 286/754 (37.93%), Postives = 447/754 (59.28%), Query Frame = 3
Query: 6150 HDLFFKLYFKAVSKICA-WNQEYPVHSVSHIRTKILEPAMGVF------GKSLKQESDMLS--TMSTFSYQQYTHINQYMRSSEYENRVKILTESKRDVSYLVDLRGKCPLRKILEKQSEVDWDELNNLS--QDRERFLLSAAISCSECLQNEDGNDFKIFHLMSMWLSNESNEKLNNIISDVIGKIETHKFLVLMPQLCARLNSE--NNKSFEINLEKLIKRIILDHPFHSIYNLLAIRNANRDXXXXXXXXXXXXXXANDKMNS-------RISVAYTMVEQLVKESQSDIIRDADILTTAYIHWANVDMSAFKQDIHKKLKFPLNCSLLRIAKQVKLPVPTLSIPIDRSLKYSLDRLPLIVGFDDVYSLQGGINLPKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKVIPMTQTSGIIEWCEDTVPLGDWLANDKTGAHQRYRPQDSTPLQCRKRLQISAEENIKKRIETFKDILTKIQPVLGYFHFEKFPESQRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAFDLGKLMPTQERVPFRLTRDLVHGLGPFGVEGRFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLHSWKLNPQHARVLHTKREADNDCXXXXXXXXXXIEGFDNKSRPGSSQNQMAERVILEMSRKFAGAVDSSYLNCEGHVNYLIQTASNVENLARMFHGWQAYL 8351
+D +L + ++C W E + S + I LE A+ V G+ L QE M + +++ FS QY I+ YM+SSE+EN+ +L ++K +V + + + R ++ Q E++ DE L+ +DR+RFL A + CL + + +D IF L S+WL N + ++N+++ +I +HKFL LM QL AR+ ++ N F L LI RI +DHP H+++ +LA+ NAN+D +L K +++K + + R+ A +V+ +K+ +++++RD + L AYI AN+D + +K + P + + ++ K + +PT+ I +D S KY + L IV F + L GG+NLPKI+ C SDG +RRQLVK DDLRQD+VMQQVF + N+LL + S T K R ++IR YKV+P++Q SG++EWC TVP+G++L N+K GAH+RYRP+D LQC++++ +++ +TF DI +PV YF EKF + WF+ R +Y S+A +SIVG+I+GLGDRHVQNIL+D +AEL+HID G+AF+ GK++PT E VPFRLTRD+V G+G GVEG F+ C + ++R+ ++ +LT++EVLL+DPL W +NP A L + E D + + D++ S N++AERV+L + K G + L+ G VN+LIQ A + +NL+R+F GW+A++
Sbjct: 2161 NDSTLRLLYAECLRLCGNWLAETCLESPTVIMQNYLEKAVEVAEYPDGAGEKL-QEGRMKAFLSLARFSDAQYQRIDNYMKSSEFENKQALLRKAKEEVGLMKQHKVQTN-RYTVKVQRELELDECAILALREDRKRFLCKAVENYISCLVSGEEHDMWIFRLCSLWLENSAVSEVNSMMRQDAQRIPSHKFLPLMYQLAARMGTKKMGNLGFHDVLNNLIGRISMDHPHHTLFIILALANANKDDQLMKPEAVKRGRLTKNAPKQISQLDEDRMEAARHIVDT-IKKQRTNMVRDVERLCDAYITLANMDANQWKSQ-RNAIPIPSDQPITKLNKLHDVVIPTMEIKVDPSGKY--ENLVTIVSFKPEFRLAGGLNLPKIIDCVGSDGKERRQLVKGRDDLRQDAVMQQVFQMCNTLL-QRNSETRK---------------RKLTIRRYKVVPLSQRSGVLEWCTGTVPIGEYLVNEKEGAHKRYRPRDYGSLQCQRKMMEVQRGRFEEKYQTFLDISENFRPVFRYFCMEKFLDPAMWFEKRLAYTRSVATSSIVGYIVGLGDRHVQNILIDEESAELVHIDLGVAFEQGKILPTPETVPFRLTRDIVDGMGITGVEGVFRRCCEKTMEVMRNNQEALLTIVEVLLYDPLFDWTMNPLKALYLQ-QDEVDFNATLGGDDPECNRNSCDSQ-----SVNKVAERVLLRLQEKLKGVEEGMVLSVGGQVNHLIQQAMDPKNLSRLFPGWKAWV 2886
BLAST of Serine-protein kinase ATM vs. Ensembl Xenopus
Match: ATM (ATM serine/threonine kinase [Source:NCBI gene;Acc:100490767]) HSP 1 Score: 488.034 bits (1255), Expect = 6.327e-138 Identity = 286/754 (37.93%), Postives = 447/754 (59.28%), Query Frame = 3
Query: 6150 HDLFFKLYFKAVSKICA-WNQEYPVHSVSHIRTKILEPAMGVF------GKSLKQESDMLS--TMSTFSYQQYTHINQYMRSSEYENRVKILTESKRDVSYLVDLRGKCPLRKILEKQSEVDWDELNNLS--QDRERFLLSAAISCSECLQNEDGNDFKIFHLMSMWLSNESNEKLNNIISDVIGKIETHKFLVLMPQLCARLNSE--NNKSFEINLEKLIKRIILDHPFHSIYNLLAIRNANRDXXXXXXXXXXXXXXANDKMNS-------RISVAYTMVEQLVKESQSDIIRDADILTTAYIHWANVDMSAFKQDIHKKLKFPLNCSLLRIAKQVKLPVPTLSIPIDRSLKYSLDRLPLIVGFDDVYSLQGGINLPKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKVIPMTQTSGIIEWCEDTVPLGDWLANDKTGAHQRYRPQDSTPLQCRKRLQISAEENIKKRIETFKDILTKIQPVLGYFHFEKFPESQRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAFDLGKLMPTQERVPFRLTRDLVHGLGPFGVEGRFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLHSWKLNPQHARVLHTKREADNDCXXXXXXXXXXIEGFDNKSRPGSSQNQMAERVILEMSRKFAGAVDSSYLNCEGHVNYLIQTASNVENLARMFHGWQAYL 8351
+D +L + ++C W E + S + I LE A+ V G+ L QE M + +++ FS QY I+ YM+SSE+EN+ +L ++K +V + + + R ++ Q E++ DE L+ +DR+RFL A + CL + + +D IF L S+WL N + ++N+++ +I +HKFL LM QL AR+ ++ N F L LI RI +DHP H+++ +LA+ NAN+D +L K +++K + + R+ A +V+ +K+ +++++RD + L AYI AN+D + +K + P + + ++ K + +PT+ I +D S KY + L IV F + L GG+NLPKI+ C SDG +RRQLVK DDLRQD+VMQQVF + N+LL + S T K R ++IR YKV+P++Q SG++EWC TVP+G++L N+K GAH+RYRP+D LQC++++ +++ +TF DI +PV YF EKF + WF+ R +Y S+A +SIVG+I+GLGDRHVQNIL+D +AEL+HID G+AF+ GK++PT E VPFRLTRD+V G+G GVEG F+ C + ++R+ ++ +LT++EVLL+DPL W +NP A L + E D + + D++ S N++AERV+L + K G + L+ G VN+LIQ A + +NL+R+F GW+A++
Sbjct: 2298 NDSTLRLLYAECLRLCGNWLAETCLESPTVIMQNYLEKAVEVAEYPDGAGEKL-QEGRMKAFLSLARFSDAQYQRIDNYMKSSEFENKQALLRKAKEEVGLMKQHKVQTN-RYTVKVQRELELDECAILALREDRKRFLCKAVENYISCLVSGEEHDMWIFRLCSLWLENSAVSEVNSMMRQDAQRIPSHKFLPLMYQLAARMGTKKMGNLGFHDVLNNLIGRISMDHPHHTLFIILALANANKDDQLMKPEAVKRGRLTKNAPKQISQLDEDRMEAARHIVDT-IKKQRTNMVRDVERLCDAYITLANMDANQWKSQ-RNAIPIPSDQPITKLNKLHDVVIPTMEIKVDPSGKY--ENLVTIVSFKPEFRLAGGLNLPKIIDCVGSDGKERRQLVKGRDDLRQDAVMQQVFQMCNTLL-QRNSETRK---------------RKLTIRRYKVVPLSQRSGVLEWCTGTVPIGEYLVNEKEGAHKRYRPRDYGSLQCQRKMMEVQRGRFEEKYQTFLDISENFRPVFRYFCMEKFLDPAMWFEKRLAYTRSVATSSIVGYIVGLGDRHVQNILIDEESAELVHIDLGVAFEQGKILPTPETVPFRLTRDIVDGMGITGVEGVFRRCCEKTMEVMRNNQEALLTIVEVLLYDPLFDWTMNPLKALYLQ-QDEVDFNATLGGDDPECNRNSCDSQ-----SVNKVAERVLLRLQEKLKGVEEGMVLSVGGQVNHLIQQAMDPKNLSRLFPGWKAWV 3023
BLAST of Serine-protein kinase ATM vs. Ensembl Xenopus
Match: ATM (ATM serine/threonine kinase [Source:NCBI gene;Acc:100490767]) HSP 1 Score: 487.649 bits (1254), Expect = 6.468e-138 Identity = 286/754 (37.93%), Postives = 447/754 (59.28%), Query Frame = 3
Query: 6150 HDLFFKLYFKAVSKICA-WNQEYPVHSVSHIRTKILEPAMGVF------GKSLKQESDMLS--TMSTFSYQQYTHINQYMRSSEYENRVKILTESKRDVSYLVDLRGKCPLRKILEKQSEVDWDELNNLS--QDRERFLLSAAISCSECLQNEDGNDFKIFHLMSMWLSNESNEKLNNIISDVIGKIETHKFLVLMPQLCARLNSE--NNKSFEINLEKLIKRIILDHPFHSIYNLLAIRNANRDXXXXXXXXXXXXXXANDKMNS-------RISVAYTMVEQLVKESQSDIIRDADILTTAYIHWANVDMSAFKQDIHKKLKFPLNCSLLRIAKQVKLPVPTLSIPIDRSLKYSLDRLPLIVGFDDVYSLQGGINLPKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKVIPMTQTSGIIEWCEDTVPLGDWLANDKTGAHQRYRPQDSTPLQCRKRLQISAEENIKKRIETFKDILTKIQPVLGYFHFEKFPESQRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAFDLGKLMPTQERVPFRLTRDLVHGLGPFGVEGRFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLHSWKLNPQHARVLHTKREADNDCXXXXXXXXXXIEGFDNKSRPGSSQNQMAERVILEMSRKFAGAVDSSYLNCEGHVNYLIQTASNVENLARMFHGWQAYL 8351
+D +L + ++C W E + S + I LE A+ V G+ L QE M + +++ FS QY I+ YM+SSE+EN+ +L ++K +V + + + R ++ Q E++ DE L+ +DR+RFL A + CL + + +D IF L S+WL N + ++N+++ +I +HKFL LM QL AR+ ++ N F L LI RI +DHP H+++ +LA+ NAN+D +L K +++K + + R+ A +V+ +K+ +++++RD + L AYI AN+D + +K + P + + ++ K + +PT+ I +D S KY + L IV F + L GG+NLPKI+ C SDG +RRQLVK DDLRQD+VMQQVF + N+LL + S T K R ++IR YKV+P++Q SG++EWC TVP+G++L N+K GAH+RYRP+D LQC++++ +++ +TF DI +PV YF EKF + WF+ R +Y S+A +SIVG+I+GLGDRHVQNIL+D +AEL+HID G+AF+ GK++PT E VPFRLTRD+V G+G GVEG F+ C + ++R+ ++ +LT++EVLL+DPL W +NP A L + E D + + D++ S N++AERV+L + K G + L+ G VN+LIQ A + +NL+R+F GW+A++
Sbjct: 2159 NDSTLRLLYAECLRLCGNWLAETCLESPTVIMQNYLEKAVEVAEYPDGAGEKL-QEGRMKAFLSLARFSDAQYQRIDNYMKSSEFENKQALLRKAKEEVGLMKQHKVQTN-RYTVKVQRELELDECAILALREDRKRFLCKAVENYISCLVSGEEHDMWIFRLCSLWLENSAVSEVNSMMRQDAQRIPSHKFLPLMYQLAARMGTKKMGNLGFHDVLNNLIGRISMDHPHHTLFIILALANANKDDQLMKPEAVKRGRLTKNAPKQISQLDEDRMEAARHIVDT-IKKQRTNMVRDVERLCDAYITLANMDANQWKSQ-RNAIPIPSDQPITKLNKLHDVVIPTMEIKVDPSGKY--ENLVTIVSFKPEFRLAGGLNLPKIIDCVGSDGKERRQLVKGRDDLRQDAVMQQVFQMCNTLL-QRNSETRK---------------RKLTIRRYKVVPLSQRSGVLEWCTGTVPIGEYLVNEKEGAHKRYRPRDYGSLQCQRKMMEVQRGRFEEKYQTFLDISENFRPVFRYFCMEKFLDPAMWFEKRLAYTRSVATSSIVGYIVGLGDRHVQNILIDEESAELVHIDLGVAFEQGKILPTPETVPFRLTRDIVDGMGITGVEGVFRRCCEKTMEVMRNNQEALLTIVEVLLYDPLFDWTMNPLKALYLQ-QDEVDFNATLGGDDPECNRNSCDSQ-----SVNKVAERVLLRLQEKLKGVEEGMVLSVGGQVNHLIQQAMDPKNLSRLFPGWKAWV 2884
BLAST of Serine-protein kinase ATM vs. Ensembl Xenopus
Match: ATM (ATM serine/threonine kinase [Source:NCBI gene;Acc:100490767]) HSP 1 Score: 487.649 bits (1254), Expect = 7.328e-138 Identity = 286/754 (37.93%), Postives = 447/754 (59.28%), Query Frame = 3
Query: 6150 HDLFFKLYFKAVSKICA-WNQEYPVHSVSHIRTKILEPAMGVF------GKSLKQESDMLS--TMSTFSYQQYTHINQYMRSSEYENRVKILTESKRDVSYLVDLRGKCPLRKILEKQSEVDWDELNNLS--QDRERFLLSAAISCSECLQNEDGNDFKIFHLMSMWLSNESNEKLNNIISDVIGKIETHKFLVLMPQLCARLNSE--NNKSFEINLEKLIKRIILDHPFHSIYNLLAIRNANRDXXXXXXXXXXXXXXANDKMNS-------RISVAYTMVEQLVKESQSDIIRDADILTTAYIHWANVDMSAFKQDIHKKLKFPLNCSLLRIAKQVKLPVPTLSIPIDRSLKYSLDRLPLIVGFDDVYSLQGGINLPKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKVIPMTQTSGIIEWCEDTVPLGDWLANDKTGAHQRYRPQDSTPLQCRKRLQISAEENIKKRIETFKDILTKIQPVLGYFHFEKFPESQRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAFDLGKLMPTQERVPFRLTRDLVHGLGPFGVEGRFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLHSWKLNPQHARVLHTKREADNDCXXXXXXXXXXIEGFDNKSRPGSSQNQMAERVILEMSRKFAGAVDSSYLNCEGHVNYLIQTASNVENLARMFHGWQAYL 8351
+D +L + ++C W E + S + I LE A+ V G+ L QE M + +++ FS QY I+ YM+SSE+EN+ +L ++K +V + + + R ++ Q E++ DE L+ +DR+RFL A + CL + + +D IF L S+WL N + ++N+++ +I +HKFL LM QL AR+ ++ N F L LI RI +DHP H+++ +LA+ NAN+D +L K +++K + + R+ A +V+ +K+ +++++RD + L AYI AN+D + +K + P + + ++ K + +PT+ I +D S KY + L IV F + L GG+NLPKI+ C SDG +RRQLVK DDLRQD+VMQQVF + N+LL + S T K R ++IR YKV+P++Q SG++EWC TVP+G++L N+K GAH+RYRP+D LQC++++ +++ +TF DI +PV YF EKF + WF+ R +Y S+A +SIVG+I+GLGDRHVQNIL+D +AEL+HID G+AF+ GK++PT E VPFRLTRD+V G+G GVEG F+ C + ++R+ ++ +LT++EVLL+DPL W +NP A L + E D + + D++ S N++AERV+L + K G + L+ G VN+LIQ A + +NL+R+F GW+A++
Sbjct: 2208 NDSTLRLLYAECLRLCGNWLAETCLESPTVIMQNYLEKAVEVAEYPDGAGEKL-QEGRMKAFLSLARFSDAQYQRIDNYMKSSEFENKQALLRKAKEEVGLMKQHKVQTN-RYTVKVQRELELDECAILALREDRKRFLCKAVENYISCLVSGEEHDMWIFRLCSLWLENSAVSEVNSMMRQDAQRIPSHKFLPLMYQLAARMGTKKMGNLGFHDVLNNLIGRISMDHPHHTLFIILALANANKDDQLMKPEAVKRGRLTKNAPKQISQLDEDRMEAARHIVDT-IKKQRTNMVRDVERLCDAYITLANMDANQWKSQ-RNAIPIPSDQPITKLNKLHDVVIPTMEIKVDPSGKY--ENLVTIVSFKPEFRLAGGLNLPKIIDCVGSDGKERRQLVKGRDDLRQDAVMQQVFQMCNTLL-QRNSETRK---------------RKLTIRRYKVVPLSQRSGVLEWCTGTVPIGEYLVNEKEGAHKRYRPRDYGSLQCQRKMMEVQRGRFEEKYQTFLDISENFRPVFRYFCMEKFLDPAMWFEKRLAYTRSVATSSIVGYIVGLGDRHVQNILIDEESAELVHIDLGVAFEQGKILPTPETVPFRLTRDIVDGMGITGVEGVFRRCCEKTMEVMRNNQEALLTIVEVLLYDPLFDWTMNPLKALYLQ-QDEVDFNATLGGDDPECNRNSCDSQ-----SVNKVAERVLLRLQEKLKGVEEGMVLSVGGQVNHLIQQAMDPKNLSRLFPGWKAWV 2933
BLAST of Serine-protein kinase ATM vs. Ensembl Xenopus
Match: ATM (ATM serine/threonine kinase [Source:NCBI gene;Acc:100490767]) HSP 1 Score: 487.649 bits (1254), Expect = 7.502e-138 Identity = 286/754 (37.93%), Postives = 447/754 (59.28%), Query Frame = 3
Query: 6150 HDLFFKLYFKAVSKICA-WNQEYPVHSVSHIRTKILEPAMGVF------GKSLKQESDMLS--TMSTFSYQQYTHINQYMRSSEYENRVKILTESKRDVSYLVDLRGKCPLRKILEKQSEVDWDELNNLS--QDRERFLLSAAISCSECLQNEDGNDFKIFHLMSMWLSNESNEKLNNIISDVIGKIETHKFLVLMPQLCARLNSE--NNKSFEINLEKLIKRIILDHPFHSIYNLLAIRNANRDXXXXXXXXXXXXXXANDKMNS-------RISVAYTMVEQLVKESQSDIIRDADILTTAYIHWANVDMSAFKQDIHKKLKFPLNCSLLRIAKQVKLPVPTLSIPIDRSLKYSLDRLPLIVGFDDVYSLQGGINLPKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKVIPMTQTSGIIEWCEDTVPLGDWLANDKTGAHQRYRPQDSTPLQCRKRLQISAEENIKKRIETFKDILTKIQPVLGYFHFEKFPESQRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAFDLGKLMPTQERVPFRLTRDLVHGLGPFGVEGRFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLHSWKLNPQHARVLHTKREADNDCXXXXXXXXXXIEGFDNKSRPGSSQNQMAERVILEMSRKFAGAVDSSYLNCEGHVNYLIQTASNVENLARMFHGWQAYL 8351
+D +L + ++C W E + S + I LE A+ V G+ L QE M + +++ FS QY I+ YM+SSE+EN+ +L ++K +V + + + R ++ Q E++ DE L+ +DR+RFL A + CL + + +D IF L S+WL N + ++N+++ +I +HKFL LM QL AR+ ++ N F L LI RI +DHP H+++ +LA+ NAN+D +L K +++K + + R+ A +V+ +K+ +++++RD + L AYI AN+D + +K + P + + ++ K + +PT+ I +D S KY + L IV F + L GG+NLPKI+ C SDG +RRQLVK DDLRQD+VMQQVF + N+LL + S T K R ++IR YKV+P++Q SG++EWC TVP+G++L N+K GAH+RYRP+D LQC++++ +++ +TF DI +PV YF EKF + WF+ R +Y S+A +SIVG+I+GLGDRHVQNIL+D +AEL+HID G+AF+ GK++PT E VPFRLTRD+V G+G GVEG F+ C + ++R+ ++ +LT++EVLL+DPL W +NP A L + E D + + D++ S N++AERV+L + K G + L+ G VN+LIQ A + +NL+R+F GW+A++
Sbjct: 2335 NDSTLRLLYAECLRLCGNWLAETCLESPTVIMQNYLEKAVEVAEYPDGAGEKL-QEGRMKAFLSLARFSDAQYQRIDNYMKSSEFENKQALLRKAKEEVGLMKQHKVQTN-RYTVKVQRELELDECAILALREDRKRFLCKAVENYISCLVSGEEHDMWIFRLCSLWLENSAVSEVNSMMRQDAQRIPSHKFLPLMYQLAARMGTKKMGNLGFHDVLNNLIGRISMDHPHHTLFIILALANANKDDQLMKPEAVKRGRLTKNAPKQISQLDEDRMEAARHIVDT-IKKQRTNMVRDVERLCDAYITLANMDANQWKSQ-RNAIPIPSDQPITKLNKLHDVVIPTMEIKVDPSGKY--ENLVTIVSFKPEFRLAGGLNLPKIIDCVGSDGKERRQLVKGRDDLRQDAVMQQVFQMCNTLL-QRNSETRK---------------RKLTIRRYKVVPLSQRSGVLEWCTGTVPIGEYLVNEKEGAHKRYRPRDYGSLQCQRKMMEVQRGRFEEKYQTFLDISENFRPVFRYFCMEKFLDPAMWFEKRLAYTRSVATSSIVGYIVGLGDRHVQNILIDEESAELVHIDLGVAFEQGKILPTPETVPFRLTRDIVDGMGITGVEGVFRRCCEKTMEVMRNNQEALLTIVEVLLYDPLFDWTMNPLKALYLQ-QDEVDFNATLGGDDPECNRNSCDSQ-----SVNKVAERVLLRLQEKLKGVEEGMVLSVGGQVNHLIQQAMDPKNLSRLFPGWKAWV 3060
BLAST of Serine-protein kinase ATM vs. Ensembl Mouse
Match: Atm (ataxia telangiectasia mutated [Source:MGI Symbol;Acc:MGI:107202]) HSP 1 Score: 481.1 bits (1237), Expect = 6.564e-136 Identity = 279/754 (37.00%), Postives = 442/754 (58.62%), Query Frame = 3
Query: 6144 RNHDLFFKLYFKAVSKIC-AWNQEYPVHSVSHIRTKILEPAMGVFG------KSLKQ-ESDMLSTMSTFSYQQYTHINQYMRSSEYENRVKILTESKRDVSYLVDLRGKCPLRKILEKQSEVDWDE--LNNLSQDRERFLLSAAISCSECLQNEDGNDFKIFHLMSMWLSNESNEKLNNIISDVIGKIETHKFLVLMPQLCARLNSE--NNKSFEINLEKLIKRIILDHPFHSIYNLLAIRNANRDX--XXXXXXXXXXXXXANDKMNSRI----SVAYTMVEQLVKESQSDIIRDADILTTAYIHWANVDMSAFKQDIHKKLKFPLNCSLLRIAKQVKLPVPTLSIPIDRSLKYSLDRLPLIVGFDDVYSLQGGINLPKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKVIPMTQTSGIIEWCEDTVPLGDWLANDKTGAHQRYRPQDSTPLQCRKRLQISAEENIKKRIETFKDILTKIQPVLGYFHFEKFPESQRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAFDLGKLMPTQERVPFRLTRDLVHGLGPFGVEGRFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLHSWKLNPQHARVLHTKREADNDCXXXXXXXXXXIEGFDNKSRPGSSQNQMAERVILEMSRKFAGAVDSSYLNCEGHVNYLIQTASNVENLARMFHGWQAYL 8351
+ +D K+ + ++C +W E + + + I LE A+ V G + L+ + +++ FS QY I YM+SSE+EN+ +L +K +V L + + + R ++ Q E++ DE L L +DR+RFL A + CL + + +D +F L S+WL N ++N ++ KI ++KFL LM QL AR+ ++ F L LI RI LDHP H+++ +LA+ NAN+D ++ I ++ K NS + + A T + ++ + +++D + L AYI AN+D S ++ K + P N + ++ + VPT+ I +D + +Y + L I F + L GG+NLPKI+ C SDG +RRQLVK DDLRQD+VMQQVF + N+LL + + T K R ++I TYKV+P++Q SG++EWC TVP+G++L N + GAH+RYRP D + QC+K++ +++ +++ +TF I +PV YF EKF + WF+ R +Y S+A +SIVG+ILGLGDRHVQNIL++ +AEL+HID G+AF+ GK++PT E VPFRL+RD+V G+G GVEG F+ C + ++RS ++ +LT++EVLL+DPL W +NP A L + E ++D ++T N + E + S S N++AERV++ + K G + + L+ G VN LIQ A + +NL+R+F GW+A++
Sbjct: 2332 KENDAGLKVIYAECLRVCGSWLAETCLENPAVIMQTYLEKAVKVAGSYDGNSRELRNGQMKAFLSLARFSDTQYQRIENYMKSSEFENKQTLLKRAKEEVGLLREHKIQTN-RYTVKVQRELELDECALRALREDRKRFLCKAVENYINCLLSGEEHDLWVFRLCSLWLENSGVSEVNGMMKKDGMKISSYKFLPLMYQLAARMGTKMTGGLGFHEVLNNLISRISLDHPHHTLFIILALANANKDEFLSKPETTRRSRITKSTSKENSHLDEDRTEAATRIIHSIRSKRCKMVKDMEALCDAYIILANMDASQWRAQ-RKGINIPANQPITKLKNLEDVVVPTMEIKVDPTGEY--ENLVTIKSFKTEFRLAGGLNLPKIIDCVGSDGKERRQLVKGRDDLRQDAVMQQVFQMCNTLL-QRNTETRK---------------RKLTICTYKVVPLSQRSGVLEWCTGTVPIGEYLVNSEDGAHRRYRPNDFSANQCQKKMMEVQKKSFEEKYDTFMTICQNFEPVFRYFCMEKFLDPAVWFEKRLAYTRSVATSSIVGYILGLGDRHVQNILINEQSAELVHIDLGVAFEQGKILPTPETVPFRLSRDIVDGMGITGVEGVFRRCCEKTMEVMRSSQETLLTIVEVLLYDPLFDWTMNPLKALYLQQRPEDESDLHSTPNADDQ--ECKQSLSDTDQSFNKVAERVLMRLQEKLKGVEEGTVLSVGGQVNLLIQQAMDPKNLSRLFPGWKAWV 3063
BLAST of Serine-protein kinase ATM vs. Ensembl Mouse
Match: Atm (ataxia telangiectasia mutated [Source:MGI Symbol;Acc:MGI:107202]) HSP 1 Score: 480.715 bits (1236), Expect = 7.414e-136 Identity = 279/754 (37.00%), Postives = 442/754 (58.62%), Query Frame = 3
Query: 6144 RNHDLFFKLYFKAVSKIC-AWNQEYPVHSVSHIRTKILEPAMGVFG------KSLKQ-ESDMLSTMSTFSYQQYTHINQYMRSSEYENRVKILTESKRDVSYLVDLRGKCPLRKILEKQSEVDWDE--LNNLSQDRERFLLSAAISCSECLQNEDGNDFKIFHLMSMWLSNESNEKLNNIISDVIGKIETHKFLVLMPQLCARLNSE--NNKSFEINLEKLIKRIILDHPFHSIYNLLAIRNANRDX--XXXXXXXXXXXXXANDKMNSRI----SVAYTMVEQLVKESQSDIIRDADILTTAYIHWANVDMSAFKQDIHKKLKFPLNCSLLRIAKQVKLPVPTLSIPIDRSLKYSLDRLPLIVGFDDVYSLQGGINLPKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKVIPMTQTSGIIEWCEDTVPLGDWLANDKTGAHQRYRPQDSTPLQCRKRLQISAEENIKKRIETFKDILTKIQPVLGYFHFEKFPESQRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAFDLGKLMPTQERVPFRLTRDLVHGLGPFGVEGRFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLHSWKLNPQHARVLHTKREADNDCXXXXXXXXXXIEGFDNKSRPGSSQNQMAERVILEMSRKFAGAVDSSYLNCEGHVNYLIQTASNVENLARMFHGWQAYL 8351
+ +D K+ + ++C +W E + + + I LE A+ V G + L+ + +++ FS QY I YM+SSE+EN+ +L +K +V L + + + R ++ Q E++ DE L L +DR+RFL A + CL + + +D +F L S+WL N ++N ++ KI ++KFL LM QL AR+ ++ F L LI RI LDHP H+++ +LA+ NAN+D ++ I ++ K NS + + A T + ++ + +++D + L AYI AN+D S ++ K + P N + ++ + VPT+ I +D + +Y + L I F + L GG+NLPKI+ C SDG +RRQLVK DDLRQD+VMQQVF + N+LL + + T K R ++I TYKV+P++Q SG++EWC TVP+G++L N + GAH+RYRP D + QC+K++ +++ +++ +TF I +PV YF EKF + WF+ R +Y S+A +SIVG+ILGLGDRHVQNIL++ +AEL+HID G+AF+ GK++PT E VPFRL+RD+V G+G GVEG F+ C + ++RS ++ +LT++EVLL+DPL W +NP A L + E ++D ++T N + E + S S N++AERV++ + K G + + L+ G VN LIQ A + +NL+R+F GW+A++
Sbjct: 2335 KENDAGLKVIYAECLRVCGSWLAETCLENPAVIMQTYLEKAVKVAGSYDGNSRELRNGQMKAFLSLARFSDTQYQRIENYMKSSEFENKQTLLKRAKEEVGLLREHKIQTN-RYTVKVQRELELDECALRALREDRKRFLCKAVENYINCLLSGEEHDLWVFRLCSLWLENSGVSEVNGMMKKDGMKISSYKFLPLMYQLAARMGTKMTGGLGFHEVLNNLISRISLDHPHHTLFIILALANANKDEFLSKPETTRRSRITKSTSKENSHLDEDRTEAATRIIHSIRSKRCKMVKDMEALCDAYIILANMDASQWRAQ-RKGINIPANQPITKLKNLEDVVVPTMEIKVDPTGEY--ENLVTIKSFKTEFRLAGGLNLPKIIDCVGSDGKERRQLVKGRDDLRQDAVMQQVFQMCNTLL-QRNTETRK---------------RKLTICTYKVVPLSQRSGVLEWCTGTVPIGEYLVNSEDGAHRRYRPNDFSANQCQKKMMEVQKKSFEEKYDTFMTICQNFEPVFRYFCMEKFLDPAVWFEKRLAYTRSVATSSIVGYILGLGDRHVQNILINEQSAELVHIDLGVAFEQGKILPTPETVPFRLSRDIVDGMGITGVEGVFRRCCEKTMEVMRSSQETLLTIVEVLLYDPLFDWTMNPLKALYLQQRPEDESDLHSTPNADDQ--ECKQSLSDTDQSFNKVAERVLMRLQEKLKGVEEGTVLSVGGQVNLLIQQAMDPKNLSRLFPGWKAWV 3066
BLAST of Serine-protein kinase ATM vs. Ensembl Mouse
Match: Atr (ataxia telangiectasia and Rad3 related [Source:MGI Symbol;Acc:MGI:108028]) HSP 1 Score: 209.534 bits (532), Expect = 2.820e-53 Identity = 154/594 (25.93%), Postives = 276/594 (46.46%), Query Frame = 3
Query: 6639 KLNNIISDVIGKIETHKFLVLMPQLCARLNSENNKSFEINLEKLIKRIILDHPFHSIYNLLAIRNANRDXXXXXXXXXXXXXXANDKMNSRISVAYTMVEQLVKESQSDIIRDADILTTAYIHWANVDMSAFKQDIHKKLKFPLNCSLLR--IAKQVKLPVPTLSIPIDRSL---KYSLDRLP----LIVGFDDVYSLQGGINLPKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKVIPMTQTSGIIEWCEDTV---PLGDWLANDK----TGAHQRYRPQDSTPLQCRKRLQISAEENIKKRIETFKDIL-TKIQPVLGYFHFEKFPESQRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAFDLGKLMPTQERVPFRLTRDLVHGLGPFGVEGRFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLHSWKLNPQHARVLHTKREADNDCXXXXXXXXXXIEGFDNKSRPGSSQNQMAERVILEMSRKFAGAVDSSY------LNCEGHVNYLIQTASNVENLARMFHGWQAYL 8351
K+N+++++ ++ ++FL QL +R+ +++ F + +E +I ++ L +P +++ + A+ ++ + ++ ++ A M K+S + DA LT + N + + F + L+ ++ +P+ ++ IP S+ + D P + GFDDV + + PK + + SDG + K DDLR+D + + S++N S+ A S + R + IRTY VIP+ GIIEW +T P+ + +K TG R QC + + ++++ F+++L + PV + FP+ W+ +R +Y S A+ S+VG+ILGLGDRH +NIL D T E +H+DF F+ G+ E VPFRLT ++V+G+GP G EG F+ C L L+R Q++ ++++++ LHDPL W P H+K + G N+ A+ +L++ ++ G + + L+ EGHV+YLIQ A++ L +M+ GW Y+
Sbjct: 2121 KINSVLTEHTNRLAPYQFLTAFSQLISRICHSHDEVFVVLME-IIAKVFLAYPQQAMWMMTAVSKSSYPMRV-------------NRCKEILTKAIHM-----KKSLEKFVGDATRLTDKLLELCNKSVDGSNSTLSMSTHFKMLKRLVEDPTFSEILIPLQSVMIPTLPSVLGAHANHDPFPGHWAYLAGFDDVVEILSSLQKPKKISLKGSDGKFYIMMCKPKDDLRKDCRLMEFNSLINK------SLRKDAESRR----------RELHIRTYAVIPLNDECGIIEWVNNTAGLRPILTKIYKEKGVYMTGKELR---------QC----MLPKSAALSEKLKVFQELLLPRHPPVFHEWFLRTFPDPTSWYSSRSAYCRSTAVMSMVGYILGLGDRHGENILFDSFTGECVHVDFNCLFNKGETFEVPEIVPFRLTHNMVNGMGPMGTEGLFRRACEVTLRLMRDQREPLMSVLKTFLHDPLVEWS-KPVKG---HSKAPLNET---------------------GEVVNEKAKTHVLDIEQRLQGVIKTRNRVTGLPLSIEGHVHYLIQEATDENLLCQMYLGWTPYM 2641
BLAST of Serine-protein kinase ATM vs. Ensembl Mouse
Match: Atr (ataxia telangiectasia and Rad3 related [Source:MGI Symbol;Acc:MGI:108028]) HSP 1 Score: 209.534 bits (532), Expect = 2.864e-53 Identity = 154/594 (25.93%), Postives = 276/594 (46.46%), Query Frame = 3
Query: 6639 KLNNIISDVIGKIETHKFLVLMPQLCARLNSENNKSFEINLEKLIKRIILDHPFHSIYNLLAIRNANRDXXXXXXXXXXXXXXANDKMNSRISVAYTMVEQLVKESQSDIIRDADILTTAYIHWANVDMSAFKQDIHKKLKFPLNCSLLR--IAKQVKLPVPTLSIPIDRSL---KYSLDRLP----LIVGFDDVYSLQGGINLPKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKVIPMTQTSGIIEWCEDTV---PLGDWLANDK----TGAHQRYRPQDSTPLQCRKRLQISAEENIKKRIETFKDIL-TKIQPVLGYFHFEKFPESQRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAFDLGKLMPTQERVPFRLTRDLVHGLGPFGVEGRFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLHSWKLNPQHARVLHTKREADNDCXXXXXXXXXXIEGFDNKSRPGSSQNQMAERVILEMSRKFAGAVDSSY------LNCEGHVNYLIQTASNVENLARMFHGWQAYL 8351
K+N+++++ ++ ++FL QL +R+ +++ F + +E +I ++ L +P +++ + A+ ++ + ++ ++ A M K+S + DA LT + N + + F + L+ ++ +P+ ++ IP S+ + D P + GFDDV + + PK + + SDG + K DDLR+D + + S++N S+ A S + R + IRTY VIP+ GIIEW +T P+ + +K TG R QC + + ++++ F+++L + PV + FP+ W+ +R +Y S A+ S+VG+ILGLGDRH +NIL D T E +H+DF F+ G+ E VPFRLT ++V+G+GP G EG F+ C L L+R Q++ ++++++ LHDPL W P H+K + G N+ A+ +L++ ++ G + + L+ EGHV+YLIQ A++ L +M+ GW Y+
Sbjct: 2115 KINSVLTEHTNRLAPYQFLTAFSQLISRICHSHDEVFVVLME-IIAKVFLAYPQQAMWMMTAVSKSSYPMRV-------------NRCKEILTKAIHM-----KKSLEKFVGDATRLTDKLLELCNKSVDGSNSTLSMSTHFKMLKRLVEDPTFSEILIPLQSVMIPTLPSVLGAHANHDPFPGHWAYLAGFDDVVEILSSLQKPKKISLKGSDGKFYIMMCKPKDDLRKDCRLMEFNSLINK------SLRKDAESRR----------RELHIRTYAVIPLNDECGIIEWVNNTAGLRPILTKIYKEKGVYMTGKELR---------QC----MLPKSAALSEKLKVFQELLLPRHPPVFHEWFLRTFPDPTSWYSSRSAYCRSTAVMSMVGYILGLGDRHGENILFDSFTGECVHVDFNCLFNKGETFEVPEIVPFRLTHNMVNGMGPMGTEGLFRRACEVTLRLMRDQREPLMSVLKTFLHDPLVEWS-KPVKG---HSKAPLNET---------------------GEVVNEKAKTHVLDIEQRLQGVIKTRNRVTGLPLSIEGHVHYLIQEATDENLLCQMYLGWTPYM 2635
BLAST of Serine-protein kinase ATM vs. Ensembl Mouse
Match: Mtor (mechanistic target of rapamycin kinase [Source:MGI Symbol;Acc:MGI:1928394]) HSP 1 Score: 154.066 bits (388), Expect = 1.855e-36 Identity = 122/411 (29.68%), Postives = 197/411 (47.93%), Query Frame = 3
Query: 7224 PKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKVIPMTQTSGIIEWCEDTVPLGDWLANDKTGAHQRYRPQDSTPLQCRKRLQISAEENIKKRIETFKDILTKIQPVLGYFH--------------FEKFPESQRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAFDLGKLMPT-QERVPFRLTRDLVHGLGPFGVEGRFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLHSWKL-------------------NPQHARVLHTKREADNDCXXXXXXXXXXIEGF--DNKSRPGSSQNQMAERVILEMSRKFAGAVDSSY---LNCEGHVNYLIQTASNVENLARMFHGW 8339
P+ + S+G + L+K ++DLRQD + Q+F +VN+LL N + K +SI+ Y VIP++ SG+I W VP D L + YR +K++ ++ E I R+ D LT +Q V + H + K P S+ WF R +Y SLA+ S+VG+ILGLGDRH N++LD + +++HIDFG F++ E++PFRLTR L + + G++G ++TTC V+ +LR KD ++ ++E ++DPL +W+L Q +L + T ++I F D +P + N+ A ++I + K G D S+ L+ V LI+ A++ ENL + + GW
Sbjct: 2169 PRKLTLMGSNGHEFVFLLKGHEDLRQDERVMQLFGLVNTLLANDPTSLRKN----------------LSIQRYAVIPLSTNSGLIGW----VPHCDTLH----ALIRDYRE--------KKKILLNIEHRIMLRMAPDYDHLTLMQKVEVFEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRTTCHTVMEVLREHKDSVMAVLEAFVYDPLLNWRLMDTNTKGNKRSRTRTDSYSAGQSVEILDGVELGEPAHKKAGTTVPESIHSFIGDGLVKP-EALNKKAIQIINRVRDKLTGR-DFSHDDTLDVPTQVELLIKQATSHENLCQCYIGW 2545
BLAST of Serine-protein kinase ATM vs. UniProt/SwissProt
Match: sp|Q6PQD5|ATM_PIG (Serine-protein kinase ATM OS=Sus scrofa OX=9823 GN=ATM PE=3 SV=2) HSP 1 Score: 486.493 bits (1251), Expect = 9.063e-137 Identity = 324/991 (32.69%), Postives = 537/991 (54.19%), Query Frame = 3
Query: 5517 EAKIDILWKLTRWGDEEKLEINNLSQENVCSLAMYDFLYS-RSEHVSEFYRN-------HVVDSCKISWDQEACFRPLIERATLFGNETSLPTILESLIRIANKSNIDQLDSSIV---WA---LIRSNRFARNLEIVNQQLLGISDLAKRCKRHEYIDFIRDMLNLHEVDNSILKCSGESSLFRTIDIFSQKT-ETEETKKSFLQLE--QFIYDSQKHILTC----QQIKR------NHDLFFKLYFKAVSKICA-WNQEYPVHSVSHIRTKILEPAMGVFGKSLKQESDMLS--------TMSTFSYQQYTHINQYMRSSEYENRVKILTESKRDVSYLVDLRGKCPLRKILEKQSEVDWDE--LNNLSQDRERFLLSAAISCSECLQNEDGNDFKIFHLMSMWLSNESNEKLNNIISDVIGKIETHKFLVLMPQLCARLNSE--NNKSFEINLEKLIKRIILDHPFHSIYNLLAIRNANRDXXXXXXXXXXXXXXAND------KMNSRISVAYTMVEQLVKESQSDIIRDADILTTAYIHWANVDMSAFKQDIHKKLKFPLNCSLLRIAKQVKLPVPTLSIPIDRSLKYSLDRLPLIVGFDDVYSLQGGINLPKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKVIPMTQTSGIIEWCEDTVPLGDWLANDKTGAHQRYRPQDSTPLQCRKRLQISAEENIKKRIETFKDILTKIQPVLGYFHFEKFPESQRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAFDLGKLMPTQERVPFRLTRDLVHGLGPFGVEGRFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLHSWKLNPQHARVLHTKREADNDCXXXXXXXXXXIEGFDNKSRPGSSQNQMAERVILEMSRKFAGAVDSSYLNCEGHVNYLIQTASNVENLARMFHGWQAYL 8351
E + W+ +W + + +N + ++Y+ L S R S FY + V + CK S + P + R G LE++ + ++S D+ S + W L++ + F+ I+ + + + L ++ + + ++D+L H V+ S+L + +++ IF K + S QLE Q + ++ L Q IK+ +D KL ++C W E + + + I LE A+ + G + +D L +++ FS QY I YM+SSE+EN+ +L +K +V L + + + R ++ Q E++ DE L L +DR+RFL A + CL + +G+D IF L S+WL N ++N ++ KI ++KFL LM QL AR+ ++ F L LI RI +DHP H+++ +LA+ NAN+D L K ++ +S + + +++ + A V ++ + ++R + L AYI AN+D + ++ K ++ P + + ++ + VPT+ I +D + +Y + I F + L GG+NLPKI+ C SDG +RRQLVK DDLRQD+VMQQVF + N+LL + + T K R ++I TYKV+P++Q SG++EWC TVP+G++L N+ TGAH+RYRP+D +P+QC+K++ + ++ +++ E F +I QPV YF EKF + WF+ R +Y S+A +SIVG+ILGLGDRHVQNIL++ +AEL+HID G+AF+ GK++PT E VPFRLTRD+V G+G GVEG F+ C + ++R+ ++ +LT++EVLL+DPL W +NP A L + E +++ ++T + E N S S N++AERV++ + K G + + L+ G VN+LIQ A + +NL+++F GW+A++
Sbjct: 2098 ELHYQVAWRNMQW--DSCVSVNKGMEGTSYHESLYNALQSLRDREFSTFYESLKYARVKEVEELCKGSLESVYSLYPTLSRLQAIGE-------LENIGELFSRSVTDRQPSEVYNKWWKHSQLLKDSDFSFQEPIMALRTVILEILMEKEMENSQRECLKDILTKHLVELSLLARTFQNTQLPERAIFQIKQYNSANCGVSEWQLEEAQVFWAKKEQSLALSILKQMIKKLDASCTENDPRLKLIHIECLRVCGTWLAETCLENPAVIMQTYLEKAVELAGNYDGESNDELRNGKMKAFLSLARFSDTQYQRIENYMKSSEFENKQALLKRAKEEVGLLREHKIQTN-RYTIKVQRELELDEGALRALKKDRKRFLCKAVENYINCLLSGEGHDMWIFRLCSLWLENSGVSEVNGMMKRDGMKIPSYKFLPLMYQLAARMGTKMMGGLGFHDVLNSLISRISVDHPHHTLFIILALANANKDEFLTKPEAARSSRITKNTPKESSQLDEDRTEAANKVICTLRNRRRQMVRSVEALCDAYIILANLDATQWRTQ-RKGIRIPADQPITKLKNLEDVVVPTMEIKVDPTGEYG--NMVTIQSFKPEFRLAGGLNLPKIIDCVGSDGKERRQLVKGRDDLRQDAVMQQVFQMCNTLL-QRNTETRK---------------RKLTICTYKVVPLSQRSGVLEWCTGTVPIGEYLVNNDTGAHKRYRPKDFSPVQCQKKMMEAQNKSFEEKYEIFMNICQNFQPVFRYFCMEKFLDPAVWFERRLAYTQSVATSSIVGYILGLGDRHVQNILINEQSAELVHIDLGVAFEQGKILPTPETVPFRLTRDIVDGMGITGVEGVFRRCCEKTMEVMRNSQETLLTIVEVLLYDPLFDWTMNPLKALYLQQRPEDESELHSTPRADDQ--ECKRNLSDTDQSFNKVAERVLMRLQEKLKGVEEGTVLSVGGQVNFLIQQAMDPKNLSKLFSGWKAWV 3057
BLAST of Serine-protein kinase ATM vs. UniProt/SwissProt
Match: sp|Q13315|ATM_HUMAN (Serine-protein kinase ATM OS=Homo sapiens OX=9606 GN=ATM PE=1 SV=4) HSP 1 Score: 483.026 bits (1242), Expect = 1.158e-135 Identity = 323/954 (33.86%), Postives = 523/954 (54.82%), Query Frame = 3
Query: 5613 AMYDFLYS-RSEHVSEFYRNHVVDSCKISWDQEACFRPLIERATLFGNETSLPTI--LESLIRIANKSNIDQLDSS--IVWA----LIRSNRFARNLEIVNQQLLGISDLAKRCKRHEYIDFIRDMLNLHEVDNSILKCSGESSLFRTIDIFSQKT-ETEETKKSFLQLE--QFIYDSQKHILTC----QQIKR------NHDLFFKLYFKAVSKICA-WNQEYPVHSVSHIRTKILEPAMGVFGKSLKQESDMLS--------TMSTFSYQQYTHINQYMRSSEYENRVKILTESKRDVSYLVDLRGKCPLRKILEKQSEVDWDEL--NNLSQDRERFLLSAAISCSECLQNEDGNDFKIFHLMSMWLSNESNEKLNNIISDVIGKIETHKFLVLMPQLCARLNSE--NNKSFEINLEKLIKRIILDHPFHSIYNLLAIRNANRDXXXXXXXXXXXXXXAND--KMNSRI----SVAYTMVEQLVKESQSDIIRDADILTTAYIHWANVDMSAFKQDIHKKLKFPLNCSLLRIAKQVKLPVPTLSIPIDRSLKYSLDRLPLIVGFDDVYSLQGGINLPKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKVIPMTQTSGIIEWCEDTVPLGDWLANDKTGAHQRYRPQDSTPLQCRKRLQISAEENIKKRIETFKDILTKIQPVLGYFHFEKFPESQRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAFDLGKLMPTQERVPFRLTRDLVHGLGPFGVEGRFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLHSWKLNPQHARVLHTKREADNDCXXXXXXXXXXIEGFDNKSRPGSSQNQMAERVILEMSRKFAGAVDSSYLNCEGHVNYLIQTASNVENLARMFHGWQAYL 8351
++Y+ L S R S FY + + ++ +E C R L +L+ + L I LES+ + ++S + S I W L++ + F+ I+ + + + L ++ + + I+D+L H V+ SIL + +++ IF K + S QLE Q + ++ L Q IK+ ++ KL + ++C W E + + + I LE A+ V G + SD L +++ FS QY I YM+SSE+EN+ +L +K +V L + + + R ++ Q E++ DEL L +DR+RFL A + CL + + +D +F L S+WL N ++N ++ KI T+KFL LM QL AR+ ++ F L LI RI +DHP H+++ +LA+ NANRD L K + + + + K +S++ + A + ++ + ++R + L AYI AN+D + +K K + P + + ++ + VPT+ I +D + +Y L I F + L GG+NLPKI+ C SDG +RRQLVK DDLRQD+VMQQVF + N+LL + + T K R ++I TYKV+P++Q SG++EWC TVP+G++L N++ GAH+RYRP D + QC+K++ +++ +++ E F D+ QPV YF EKF + WF+ R +Y S+A +SIVG+ILGLGDRHVQNIL++ +AEL+HID G+AF+ GK++PT E VPFRLTRD+V G+G GVEG F+ C + ++R+ ++ +LT++EVLL+DPL W +NP A L+ ++ +++ ++ E N S S N++AERV++ + K G + + L+ G VN LIQ A + +NL+R+F GW+A++
Sbjct: 2127 SLYNALQSLRDREFSTFYES--LKYARVKEVEEMCKRSLESVYSLYPTLSRLQAIGELESIGELFSRSVTHRQLSEVYIKWQKHSQLLKDSDFSFQEPIMALRTVILEILMEKEMDNSQRECIKDILTKHLVELSILARTFKNTQLPERAIFQIKQYNSVSCGVSEWQLEEAQVFWAKKEQSLALSILKQMIKKLDASCAANNPSLKLTYTECLRVCGNWLAETCLENPAVIMQTYLEKAVEVAGNYDGESSDELRNGKMKAFLSLARFSDTQYQRIENYMKSSEFENKQALLKRAKEEVGLLREHKIQTN-RYTVKVQRELELDELALRALKEDRKRFLCKAVENYINCLLSGEEHDMWVFRLCSLWLENSGVSEVNGMMKRDGMKIPTYKFLPLMYQLAARMGTKMMGGLGFHEVLNNLISRISMDHPHHTLFIILALANANRDEFLTKPEVARRSRITKNVPKQSSQLDEDRTEAANRIICTIRSRRPQMVRSVEALCDAYIILANLDATQWKTQ-RKGINIPADQPITKLKNLEDVVVPTMEIKVDHTGEYG--NLVTIQSFKAEFRLAGGVNLPKIIDCVGSDGKERRQLVKGRDDLRQDAVMQQVFQMCNTLL-QRNTETRK---------------RKLTICTYKVVPLSQRSGVLEWCTGTVPIGEFLVNNEDGAHKRYRPNDFSAFQCQKKMMEVQKKSFEEKYEVFMDVCQNFQPVFRYFCMEKFLDPAIWFEKRLAYTRSVATSSIVGYILGLGDRHVQNILINEQSAELVHIDLGVAFEQGKILPTPETVPFRLTRDIVDGMGITGVEGVFRRCCEKTMEVMRNSQETLLTIVEVLLYDPLFDWTMNPLKA--LYLQQRPEDETELHPTLNADDQECKRNLSDIDQSFNKVAERVLMRLQEKLKGVEEGTVLSVGGQVNLLIQQAIDPKNLSRLFPGWKAWV 3056
BLAST of Serine-protein kinase ATM vs. UniProt/SwissProt
Match: sp|Q62388|ATM_MOUSE (Serine-protein kinase ATM OS=Mus musculus OX=10090 GN=Atm PE=1 SV=2) HSP 1 Score: 480.715 bits (1236), Expect = 5.186e-135 Identity = 279/754 (37.00%), Postives = 442/754 (58.62%), Query Frame = 3
Query: 6144 RNHDLFFKLYFKAVSKIC-AWNQEYPVHSVSHIRTKILEPAMGVFG------KSLKQ-ESDMLSTMSTFSYQQYTHINQYMRSSEYENRVKILTESKRDVSYLVDLRGKCPLRKILEKQSEVDWDE--LNNLSQDRERFLLSAAISCSECLQNEDGNDFKIFHLMSMWLSNESNEKLNNIISDVIGKIETHKFLVLMPQLCARLNSE--NNKSFEINLEKLIKRIILDHPFHSIYNLLAIRNANRDX--XXXXXXXXXXXXXANDKMNSRI----SVAYTMVEQLVKESQSDIIRDADILTTAYIHWANVDMSAFKQDIHKKLKFPLNCSLLRIAKQVKLPVPTLSIPIDRSLKYSLDRLPLIVGFDDVYSLQGGINLPKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKVIPMTQTSGIIEWCEDTVPLGDWLANDKTGAHQRYRPQDSTPLQCRKRLQISAEENIKKRIETFKDILTKIQPVLGYFHFEKFPESQRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAFDLGKLMPTQERVPFRLTRDLVHGLGPFGVEGRFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLHSWKLNPQHARVLHTKREADNDCXXXXXXXXXXIEGFDNKSRPGSSQNQMAERVILEMSRKFAGAVDSSYLNCEGHVNYLIQTASNVENLARMFHGWQAYL 8351
+ +D K+ + ++C +W E + + + I LE A+ V G + L+ + +++ FS QY I YM+SSE+EN+ +L +K +V L + + + R ++ Q E++ DE L L +DR+RFL A + CL + + +D +F L S+WL N ++N ++ KI ++KFL LM QL AR+ ++ F L LI RI LDHP H+++ +LA+ NAN+D ++ I ++ K NS + + A T + ++ + +++D + L AYI AN+D S ++ K + P N + ++ + VPT+ I +D + +Y + L I F + L GG+NLPKI+ C SDG +RRQLVK DDLRQD+VMQQVF + N+LL + + T K R ++I TYKV+P++Q SG++EWC TVP+G++L N + GAH+RYRP D + QC+K++ +++ +++ +TF I +PV YF EKF + WF+ R +Y S+A +SIVG+ILGLGDRHVQNIL++ +AEL+HID G+AF+ GK++PT E VPFRL+RD+V G+G GVEG F+ C + ++RS ++ +LT++EVLL+DPL W +NP A L + E ++D ++T N + E + S S N++AERV++ + K G + + L+ G VN LIQ A + +NL+R+F GW+A++
Sbjct: 2335 KENDAGLKVIYAECLRVCGSWLAETCLENPAVIMQTYLEKAVKVAGSYDGNSRELRNGQMKAFLSLARFSDTQYQRIENYMKSSEFENKQTLLKRAKEEVGLLREHKIQTN-RYTVKVQRELELDECALRALREDRKRFLCKAVENYINCLLSGEEHDLWVFRLCSLWLENSGVSEVNGMMKKDGMKISSYKFLPLMYQLAARMGTKMTGGLGFHEVLNNLISRISLDHPHHTLFIILALANANKDEFLSKPETTRRSRITKSTSKENSHLDEDRTEAATRIIHSIRSKRCKMVKDMEALCDAYIILANMDASQWRAQ-RKGINIPANQPITKLKNLEDVVVPTMEIKVDPTGEY--ENLVTIKSFKTEFRLAGGLNLPKIIDCVGSDGKERRQLVKGRDDLRQDAVMQQVFQMCNTLL-QRNTETRK---------------RKLTICTYKVVPLSQRSGVLEWCTGTVPIGEYLVNSEDGAHRRYRPNDFSANQCQKKMMEVQKKSFEEKYDTFMTICQNFEPVFRYFCMEKFLDPAVWFEKRLAYTRSVATSSIVGYILGLGDRHVQNILINEQSAELVHIDLGVAFEQGKILPTPETVPFRLSRDIVDGMGITGVEGVFRRCCEKTMEVMRSSQETLLTIVEVLLYDPLFDWTMNPLKALYLQQRPEDESDLHSTPNADDQ--ECKQSLSDTDQSFNKVAERVLMRLQEKLKGVEEGTVLSVGGQVNLLIQQAMDPKNLSRLFPGWKAWV 3066
BLAST of Serine-protein kinase ATM vs. UniProt/SwissProt
Match: sp|Q9M3G7|ATM_ARATH (Serine/threonine-protein kinase ATM OS=Arabidopsis thaliana OX=3702 GN=ATM PE=1 SV=1) HSP 1 Score: 385.956 bits (990), Expect = 6.664e-106 Identity = 226/646 (34.98%), Postives = 352/646 (54.49%), Query Frame = 3
Query: 6465 LEKQSEVDWDELNNLSQDRERFLLSAAISCSECLQNEDGNDFKI-FHLMSMWLSNESNEKLNNIISDVIGKIETHKFLVLMPQLCARLNSENNKS----FEINLEKLIKRIILDHPFHSIYNLLAIRNANRDXXXXXXXXXXXXXXANDKMNSRISVAYTMVEQLVKES--------QSDIIRDADILTTAYIHWANVDMSAFKQDIHKKLKFPLNCSLLRIAKQVKL-PVPTLSIPIDRSLKYSLDRLPLIVGFDDVYSLQGGINLPKIVWCQSSDGLKRRQLVKS-NDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKVIPMTQTSGIIEWCEDTVPLGDWL--ANDKTGAHQRYRPQDSTPLQCRKRLQISAEENIKKRIETFKDILTKIQPVLGYFHFEKFPESQRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAFDLGKLMPTQERVPFRLTRDLVHGLGPFGVEGRFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLHSWKLNPQHARVLHTKREADNDCXXXXXXXXXXIEGFDNKSRPGSSQNQMAERVILEMSRKFAGAVDSSYLNCEGHVNYLIQTASNVENLARMFHGWQAYL 8351
L+KQ +D +E L DR+ FL A CL+ D D ++ F +SMW S S + + + + I +++++KF+ L+ Q+ +RL S ++S F+ L LI+++ +DHP+H+I LLA+ N +R D SR S M ++L E +IR L YI A ++ ++D ++K+ P +R KQ++L PV T +IP+DRS +Y+ P G D ++ GIN PK+V C SDG K +QL KS NDDLRQD+VM+Q F +VN+ L N + R +++RTYKVIP T ++G++EW + T+PLGD+L ++ GAH RY + +CR+ + + K + + F D+ T +PV+ YF EKF + WF R +Y S+A +S+VG+I+GLGDRH NIL+D TAE++HID G+AF+ G ++ T ERVPFRLTRD++ G+G GVEG F+ C + L+++R+ K+ +LT++EV +HDPL+ W L+P A L ++E ++ + EG N+ A R ++ + +K G + G LIQ A + + L+ MF GW A++
Sbjct: 3265 LQKQLTMDKEEAEKLQVDRDNFLKLALEGYKRCLEIGDKYDVRVVFRQVSMWFSLASQKNVIDNMLSTIKEVQSYKFIPLVYQIASRLGSSKDESGSNSFQSALVSLIRKMAIDHPYHTILQLLALANGDR---------------IKDNQRSRNSFVVDMDKKLAAEHLLQDVSHYHGPMIRQMKQLVDIYIKLAELETR--REDTNRKVALPRE---IRSVKQLELVPVVTATIPVDRSCQYNEGSFPFFRGLSDSVTVMNGINAPKVVECFGSDGQKYKQLAKSGNDDLRQDAVMEQFFGLVNTFLHNNRDT----------------WKRRLAVRTYKVIPFTPSAGVLEWVDGTIPLGDYLIGSSRSEGAHGRYGIGNWKYPKCREHMS-----SAKDKRKAFVDVCTNFRPVMHYFFLEKFLQPADWFVKRLAYTRSVAASSMVGYIVGLGDRHAMNILIDQATAEVVHIDLGVAFEQGLMLKTPERVPFRLTRDIIDGMGITGVEGVFRRCCEETLSVMRTNKEALLTIVEVFIHDPLYKWALSPLKA--LQRQKETEDYDGMNLEGLQEEFEG-----------NKDATRALMRVKQKLDGYEGGEMRSIHGQAQQLIQDAIDTDRLSHMFPGWGAWM 3856
BLAST of Serine-protein kinase ATM vs. UniProt/SwissProt
Match: sp|Q5EAK6|ATM_DROME (Serine/threonine-protein kinase ATM OS=Drosophila melanogaster OX=7227 GN=tefu PE=2 SV=1) HSP 1 Score: 337.421 bits (864), Expect = 3.249e-91 Identity = 226/699 (32.33%), Postives = 348/699 (49.79%), Query Frame = 3
Query: 6288 KQESDMLSTMSTFSYQQYTHINQYMRSSEYENRVKILTESKRDVSYLVDLRGKCPLRKI---LEKQSEVDWDELNNLSQDRERFL-LSAAISCSECLQNEDGNDFKIFHLMSMWLSNESNEKLNNIISDVIGKIETHKFLVLMPQLCARLNSENNKSFEINLEKLIKRIILDHPFHSIYNLLAIRNANRDXXXXXXXXXXXXXXANDKMNSRISVAYTMVEQLVKE--SQSDIIRDADILTTAYIHWANVDMSAFKQDIHKKLKFPLNCSLLRIAKQVKLPVPTLSIPIDRSLKYSLDRLPLIVGFDDVYSLQGGINLPKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKVIPMTQTSGIIEWCEDTVPLGDWLA-NDKTGAHQRYRPQDSTPLQCRKRLQISAEENIKKRIETFKDILTKIQPVLGYFHFEKFPESQRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAFDLGKLMPTQERVPFRLTRDLVHGLGPFGVEGRFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLHSWKLNPQHARVLHTKREADNDCXXXXXXXXXXIEGFDNKSRPGSSQNQMAERVILEMSRKF----AGAVDSSYLNCEGHVNYLIQTASNVENLARMFHGWQAYL 8351
KQ + +T++ ++ ++Y ++ Y S EY+ +K + E R + V R R I +++ + +D +LN + + +L L+ + C + + I+ ++S+W +N ++++ I D I + ++KF+ QL ARLNS+N S L L+ + DHP+H+ Y L + A+ D + R +A ++ + ++ + + + + L A I +AN + + + ++ + R + PTL +P+ S +YS+ +V + + + GG+N P + C SDG R QLVK DDLRQD+VMQQVF +VN LL S FI R + +RTYKV P++ SGI+EWC ++VP+G +L K GAH RYRP D +CRK + + R +K I I+PV YF EKFP WF+ R +Y NS+A S+VG++LGLGDRH QNIL+D TAE+IHIDFGIAF+ GK+ T E VPFRLTRD V +G G +G F +C +++LR K + T++EVLL+DPL W VL K+ + S N +A+R +L + K AG + S N E V LI A+ NL +F GW +L
Sbjct: 2133 KQRTAAYATIAKYADREYQQLHDYRHSQEYQT-LKDIIEQNRQTAEKVTQRENQDRRVISVQMKRYASLDEQQLNQIEEKLTEYLRLALTNYMAYCRLDSGFSSAAIYRIISLWFTNATSKQCQECIKDEILTVPSYKFICAANQLTARLNSKNT-SLLKGLTDLLVQCGKDHPYHTFYQLYPLVFAHLD--------------GENSNTERSGIARKIIAMICEKNGTAGECSKQLESLLPALITFANEGKTNDNRPVSDSVRNKQFDKVRRWRNLNAVHCPTLELPVMPSKEYSIIS---VVKWTNETTQCGGLNAPVKIMCVCSDGKIRAQLVKGKDDLRQDAVMQQVFGIVNELLNQD---------------SEFI-ERKLKLRTYKVTPLSMRSGILEWCTNSVPVGHYLVVEGKGGAHARYRPNDWNNNKCRKLSSDHLKSPKETRYAIYKKICENIKPVFHYFLLEKFPIPGVWFERRLAYTNSVATTSMVGYVLGLGDRHTQNILVDQQTAEVIHIDFGIAFEQGKIQTTPETVPFRLTRDFVAPMGICGTKGVFAKSCEATMHILRRYKSVFTTILEVLLYDPLFIWG-------VLKKKQSP--------------------QQSGEESVNLVAQRALLLVQNKLDGREAGTMGDS--NVEAQVERLINEATLPSNLCMLFPGWDPHL 2767
BLAST of Serine-protein kinase ATM vs. TrEMBL
Match: M1EFK0 (Ataxia telangiectasia mutated (Fragment) OS=Mustela putorius furo OX=9669 PE=2 SV=1) HSP 1 Score: 481.485 bits (1238), Expect = 1.992e-144 Identity = 280/755 (37.09%), Postives = 440/755 (58.28%), Query Frame = 3
Query: 6150 HDLFFKLYFKAVSKICA-WNQEYPVHSVSHIRTKILEPAMGVFGKSLKQESDMLS--------TMSTFSYQQYTHINQYMRSSEYENRVKILTESKRDVSYLVDLRGKCPLRKILEKQSEVDWDE--LNNLSQDRERFLLSAAISCSECLQNEDGNDFKIFHLMSMWLSNESNEKLNNIISDVIGKIETHKFLVLMPQLCARLNSE--NNKSFEINLEKLIKRIILDHPFHSIYNLLAIRNANRDXXXXXXXXX------XXXXXANDKMNSRISVAYTMVEQLVKESQSDIIRDADILTTAYIHWANVDMSAFKQDIHKKLKFPLNCSLLRIAKQVKLPVPTLSIPIDRSLKYSLDRLPLIVGFDDVYSLQGGINLPKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKVIPMTQTSGIIEWCEDTVPLGDWLANDKTGAHQRYRPQDSTPLQCRKRLQISAEENIKKRIETFKDILTKIQPVLGYFHFEKFPESQRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAFDLGKLMPTQERVPFRLTRDLVHGLGPFGVEG---RFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLHSWKLNPQHARVLHTKREADNDCXXXXXXXXXXIEGFDNKSRPGSSQNQMAERVILEMSRKFAGAVDSSYLNCEGHVNYLIQTASNVENLARMFHGWQAY 8348
+D +L + ++C W E + + + I LE A+ V + SD L +++ FS QY I YM+SSE+EN+ +L +K +V L + + + R ++ Q E++ DE L L +DR+RFL A + CL + +G+D IF L S+WL N +N ++ KI ++KFL LM QL AR+ ++ F L LI RI +DHP H+++ +LA+ NAN+D L K ++ K+ + + ++ + A + ++ + ++R + L AYI AN+D + +K K + P + + ++ + VPT+ I +D + +Y L I F + L GG+NLPKI+ C SDG +RRQLVK DDLRQD+VMQQVF + N+LL + + T K R ++I TYKV+P++Q SG++EWC TVP+G++L N++ GAH+RYRP+D + + C+K++ +++ +++ +TF D+ K QPV YF EKF + WF+ R +Y S+A +SIVG+ILGLGDRHVQNIL++ +AEL+HID G+AF+ GK++PT E VPFRLTRD+V G+G GVEG RF+ C + ++RS ++ +LT++EVLL+DPL W +NP A L+ ++ ++D S + + E N S S N++AERV++ + K G + + L+ G VN LIQ A + +NL+R+F GW+A+
Sbjct: 27 NDPDLRLIYAECLRVCGTWLAETCLENPAVIMQTYLEKAVEVARNYDGESSDELRNGKMKAFLSLARFSDTQYQRIENYMKSSEFENKQALLKRAKEEVGLLREHKIQTN-RYTVKVQRELELDECALRALKEDRKRFLCKAVENYISCLLSGEGHDMWIFRLCSLWLENSGVSDVNGMMKTDGMKIPSYKFLPLMYQLAARMGTKMMGGLGFHEVLNNLISRISMDHPHHTLFIILALANANKDEFLTKPEAARRNRIIKNAPKQSSPLDEDRTEAANRIIHTIRSRRPQMVRSVEALCDAYIILANLDAAQWKTQ-RKGINIPADQPITKLKNLEDVVVPTMEIKVDPTGEYR--NLVTIESFKAEFRLAGGLNLPKIIDCLGSDGKERRQLVKGRDDLRQDAVMQQVFQMCNTLL-QRNTETRK---------------RKLTICTYKVVPLSQRSGVLEWCTGTVPIGEFLVNNENGAHKRYRPKDLSAIHCQKKMMDVQKKSFEEKYKTFMDVCQKFQPVFRYFCMEKFLDPAVWFEKRLAYTRSVATSSIVGYILGLGDRHVQNILINEQSAELVHIDLGVAFEQGKILPTPETVPFRLTRDIVDGMGITGVEGVFRRFRRCCEKTMEVMRSSQETLLTIVEVLLYDPLFDWTMNPLKA--LYLQQRPEDDTELQSTPAGEDQECKRNLSDTDQSFNKVAERVLMRLQEKLKGVEEGTVLSVGGQVNLLIQQAMDPKNLSRLFPGWKAW 759
BLAST of Serine-protein kinase ATM vs. TrEMBL
Match: Q6NX74 (Atm protein (Fragment) OS=Mus musculus OX=10090 GN=Atm PE=2 SV=1) HSP 1 Score: 481.485 bits (1238), Expect = 4.589e-144 Identity = 279/754 (37.00%), Postives = 442/754 (58.62%), Query Frame = 3
Query: 6144 RNHDLFFKLYFKAVSKIC-AWNQEYPVHSVSHIRTKILEPAMGVFG------KSLKQ-ESDMLSTMSTFSYQQYTHINQYMRSSEYENRVKILTESKRDVSYLVDLRGKCPLRKILEKQSEVDWDE--LNNLSQDRERFLLSAAISCSECLQNEDGNDFKIFHLMSMWLSNESNEKLNNIISDVIGKIETHKFLVLMPQLCARLNSE--NNKSFEINLEKLIKRIILDHPFHSIYNLLAIRNANRDX--XXXXXXXXXXXXXANDKMNSRI----SVAYTMVEQLVKESQSDIIRDADILTTAYIHWANVDMSAFKQDIHKKLKFPLNCSLLRIAKQVKLPVPTLSIPIDRSLKYSLDRLPLIVGFDDVYSLQGGINLPKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKVIPMTQTSGIIEWCEDTVPLGDWLANDKTGAHQRYRPQDSTPLQCRKRLQISAEENIKKRIETFKDILTKIQPVLGYFHFEKFPESQRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAFDLGKLMPTQERVPFRLTRDLVHGLGPFGVEGRFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLHSWKLNPQHARVLHTKREADNDCXXXXXXXXXXIEGFDNKSRPGSSQNQMAERVILEMSRKFAGAVDSSYLNCEGHVNYLIQTASNVENLARMFHGWQAYL 8351
+ +D K+ + ++C +W E + + + I LE A+ V G + L+ + +++ FS QY I YM+SSE+EN+ +L +K +V L + + + R ++ Q E++ DE L L +DR+RFL A + CL + + +D +F L S+WL N ++N ++ KI ++KFL LM QL AR+ ++ F L LI RI LDHP H+++ +LA+ NAN+D ++ I ++ K NS + + A T + ++ + +++D + L AYI AN+D S ++ K + P N + ++ + VPT+ I +D + +Y + L I F + L GG+NLPKI+ C SDG +RRQLVK DDLRQD+VMQQVF + N+LL + + T K R ++I TYKV+P++Q SG++EWC TVP+G++L N + GAH+RYRP D + QC+K++ +++ +++ +TF I +PV YF EKF + WF+ R +Y S+A +SIVG+ILGLGDRHVQNIL++ +AEL+HID G+AF+ GK++PT E VPFRL+RD+V G+G GVEG F+ C + ++RS ++ +LT++EVLL+DPL W +NP A L + E ++D ++T N + E + S S N++AERV++ + K G + + L+ G VN LIQ A + +NL+R+F GW+A++
Sbjct: 59 KENDAGLKVIYAECLRVCGSWLAETCLENPAVIMQTYLEKAVKVAGSYDGNSRELRNGQMKAFLSLARFSDTQYQRIENYMKSSEFENKQTLLKRAKEEVGLLREHKIQTN-RYTVKVQRELELDECALRALREDRKRFLCKAVENYINCLLSGEEHDLWVFRLCSLWLENSGVSEVNGMMKKDGMKISSYKFLPLMYQLAARMGTKMTGGLGFHEVLNNLISRISLDHPHHTLFIILALANANKDEFLSKPETTRRSRITKSTSKENSHLDEDRTEAATRIIHSIRSKRCKMVKDMEALCDAYIILANMDASQWRAQ-RKGINIPANQPITKLKNLEDVVVPTMEIKVDPTGEY--ENLVTIKSFKTEFRLAGGLNLPKIIDCVGSDGKERRQLVKGRDDLRQDAVMQQVFQMCNTLL-QRNTETRK---------------RKLTICTYKVVPLSQRSGVLEWCTGTVPIGEYLVNSEDGAHRRYRPNDFSANQCQKKMMEVQKKSFEEKYDTFMTICQNFEPVFRYFCMEKFLDPAVWFEKRLAYTRSVATSSIVGYILGLGDRHVQNILINEQSAELVHIDLGVAFEQGKILPTPETVPFRLSRDIVDGMGITGVEGVFRRCCEKTMEVMRSSQETLLTIVEVLLYDPLFDWTMNPLKALYLQQRPEDESDLHSTPNADDQ--ECKQSLSDTDQSFNKVAERVLMRLQEKLKGVEEGTVLSVGGQVNLLIQQAMDPKNLSRLFPGWKAWV 790
BLAST of Serine-protein kinase ATM vs. TrEMBL
Match: S4RPL8 (Uncharacterized protein OS=Petromyzon marinus OX=7757 PE=3 SV=1) HSP 1 Score: 489.574 bits (1259), Expect = 3.193e-143 Identity = 278/769 (36.15%), Postives = 443/769 (57.61%), Query Frame = 3
Query: 6159 FFKLYFKAVSKICAWNQEYPVHSVSHIRTKILEPAMGVFGKSLKQ--------------ESDMLSTMSTFSYQQYTHINQYMRSSEYENRVKILTESKRDVSYLVDLRGKCPLRKILEKQSEVDWDE--LNNLSQDRERFLLSAAISCSECLQNEDGN-DFKIFHLMSMWLSNESNEKLNNIISDVIGKIETHKFLVLMPQLCARLNSE--NNKSFEINLEKLIKRIILDHPFHSIYNLLAIRNANRDXXXXXXXXXXXXXXA-----NDKMNS-------RISVAYTMVEQLVKESQSDIIRDADILTTAYIHWANVDMSAFKQDIHKKLKFPLNCSLLRIAKQVKLPVPTLSIPIDRSLKYSLDRLPLIVGFDDVYSLQGGINLPKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKVIPMTQTSGIIEWCEDTVPLGDWLANDKTGAHQRYRPQDSTPLQCRKRLQISAEENIKKRI-ETFKDILTKIQPVLGYFHFEKFPESQRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAFDLGKLMPTQERVPFRLTRDLVHGLGPFGVEGRFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLHSWKLNPQHARVLHTKREADNDCXXXXXXXXXXIEGFD---NKSRPG---SSQNQMAERVILEMSRKFAGAVDSSYLNCEGHVNYLIQTASNVENLARMFHGWQAYL 8351
LY + + + W E S S I ++ LE ++ V ++ + + +++ F+ Q+ I YMRS+EYEN+ +L ++K DV+ L L+ + P R +++ Q E D DE L +L QDRERFL+ A ++ CL++ + + + F L+S+WL N + +++N+++ + I HKFL L+ QL AR+ ++ ++F L+KLI R+ L HP H++ +LA+ NA +D L+ + + D S R+ +VEQ V++ Q +++RD + L AYI AN++ A+++ K + P + + I K+ +PTL + +D + +Y L + F + L GG+NLPKI+ C+ SDG RQLVK DDLRQD+VMQQVF + N LL SA R +SIRTYKV+P++Q SG++EWC T+P+GD+L TGAH +YRP D + CRK + ++A++ + ++++ +PV +F +E+F + WF+ R SY S+A +SIVG+I+GLGDRHVQNIL+D+N+AEL+HID G+AF+ G+++PT E VPFRLTRD+V G+G GVEG F+ C + ++R+ ++ +LT++EVLL DPL W +NP A L T+ E + + +T + ++ R G S N+MAERV++ + +K G + S L+ G VN LIQ A++ +NL+R+F GWQ ++
Sbjct: 355 LLALYAECLGRYGHWLAETCSESPSIILSEYLEKSVSVAERAWGDGSGGSDEGEGGRVCRAALYLSLARFADAQHRSIVAYMRSAEYENKRALLRKAKEDVTLLQSLKLQ-PSRYMVKLQRECDLDERELLSLRQDRERFLVEALVNYVRCLRSGGAHGEARAFRLVSLWLENSAEQQVNDVMRTGVTDIPPHKFLPLIYQLAARMGTKMAGGEAFHSILQKLILRVTLTHPHHALLVVLALANAGKDELLQTVAARDGARGGSRLSRGDSKGSSAPSDDDRVRATRALVEQ-VRKQQPELVRDTEKLCDAYIMLANMNAEAWRKQT-KDMLIPKDQPIKEIRNLYKVVIPTLELKVDPTGQYP--DLVTVRAFRPHFRLAGGVNLPKIIDCEGSDGRTYRQLVKGRDDLRQDAVMQQVFHMCNELLAG----------------SAETRTRKLSIRTYKVVPLSQRSGVLEWCVGTMPIGDYLVQKDTGAHTKYRPNDWPSMHCRKFMNVAAQDRRNGDLFLAYQELCHHFRPVFRHFFWERFLDPAVWFERRLSYTRSVATSSIVGYIVGLGDRHVQNILIDLNSAELVHIDLGVAFEQGRILPTPETVPFRLTRDIVDGMGITGVEGVFRRCCEKTMEVMRNSQEALLTIVEVLLFDPLFDWTMNPLKALTLQTRTEDETEGTSTMGPTLGKAPASGRAVHQERNGMDPQSLNKMAERVLMRLQQKLKGVEEGSVLSVPGQVNLLIQQATDPKNLSRLFPGWQPWV 1102
BLAST of Serine-protein kinase ATM vs. TrEMBL
Match: A0A2Y9RMH1 (serine-protein kinase ATM-like OS=Trichechus manatus latirostris OX=127582 GN=LOC111821652 PE=3 SV=1) HSP 1 Score: 474.167 bits (1219), Expect = 1.061e-142 Identity = 266/690 (38.55%), Postives = 418/690 (60.58%), Query Frame = 3
Query: 6312 TMSTFSYQQYTHINQYMRSSEYENRVKILTESKRDVSYLVDLRGKCPLRKILEKQSEVDWDE--LNNLSQDRERFLLSAAISCSECLQNEDGNDFKIFHLMSMWLSNESNEKLNNIISDVIGKIETHKFLVLMPQLCARLNSE--NNKSFEINLEKLIKRIILDHPFHSIYNLLAIRNANRDXXXXXXXXXXXXXXAND--KMNSRI----SVAYTMVEQLVKESQSDIIRDADILTTAYIHWANVDMSAFKQDIHKKLKFPLNCSLLRIAKQVKLPVPTLSIPIDRSLKYSLDRLPLIVGFDDVYSLQGGINLPKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKVIPMTQTSGIIEWCEDTVPLGDWLANDKTGAHQRYRPQDSTPLQCRKRLQISAEENIKKRIETFKDILTKIQPVLGYFHFEKFPESQRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAFDLGKLMPTQERVPFRLTRDLVHGLGPFGVEGRFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLHSWKLNPQHARVLHTKREADNDCXXXXXXXXXXIEGFDNKSRPGSSQNQMAERVILEMSRKFAGAVDSSYLNCEGHVNYLIQTASNVENLARMFHGWQAYL 8351
+++ FS QY I YM+SSE+EN+ +L +K +V L + + + R ++ Q E++ DE L L +DR+RFL A + CL + + +D +F L S+WL N S ++N ++ V KI ++KFL LM QL AR+ ++ F L LI RI +DHP H+++ +LA+ NAN+D L K ++ + + + K +S++ + A + +K + ++R+ + L AYI AN+D S +K K + P + + ++ + VPT+ I +D + +Y L I F + L GG+NLPKI+ C SDG +RRQLVK DDLRQD+VMQQVF + N+LL + + T K R ++I TYKV+P++Q SG++EWC TVP+G++L N++ GAH+RYRP+D + QC+K++ +++ +++ F DI QPV YF EKF + WF+ R +Y S+A +SIVG+ILGLGDRHVQNIL++ +AEL+HID G+AF+ GK++PT E VPFRLTRD+V G+G GVEG F+ C + ++R+ ++ +LT++EVLL+DPL W +NP A L+ ++ +++ S ++ E N S S N++AERV++ + K G + + L+ G VN LIQ A + +NL+ +F GW+A++
Sbjct: 33 SLARFSDTQYQRIENYMKSSEFENKQALLKRAKEEVGLLKEHKIQTT-RYTVKVQRELELDECALQALKEDRKRFLCKAVENYINCLLSGEEHDMWVFRLCSLWLENASISEVNGMMKRVGMKIPSYKFLPLMYQLAARMGTKMMGGLGFHEVLNNLISRISVDHPHHTLFIILALANANKDEFLTKPEAARRNRITKNAPKQSSQLDEDRTEAANKIICTIKSRRPQMVRNVEALCDAYILLANLDASQWKTQ-RKGINIPADQPITKLKNLEDVVVPTMEIKVDPTGEYG--NLVTIQSFKAEFRLAGGLNLPKIIDCVGSDGKERRQLVKGRDDLRQDAVMQQVFQMCNTLL-QRNTETRK---------------RKLTICTYKVVPLSQRSGVLEWCTGTVPIGEFLVNNEDGAHKRYRPKDFSAYQCQKKMMEVQKKSFEEKYAAFMDICQNFQPVFRYFCMEKFLDPAVWFEKRLAYTRSVATSSIVGYILGLGDRHVQNILINEQSAELVHIDLGVAFEQGKILPTPETVPFRLTRDIVDGMGITGVEGVFRRCCEKTMEVMRNSQETLLTIVEVLLYDPLFDWTMNPLKA--LYLQQRPEDETELNSTLNADDQECKRNVSDIDQSFNKVAERVLMRLQEKLKGVEEGTVLSVGGQVNLLIQQAMDPKNLSWLFPGWKAWV 700
BLAST of Serine-protein kinase ATM vs. TrEMBL
Match: A0A5K4FBY7 (Uncharacterized protein OS=Schistosoma mansoni OX=6183 PE=4 SV=1) HSP 1 Score: 510.76 bits (1314), Expect = 3.066e-142 Identity = 297/828 (35.87%), Postives = 454/828 (54.83%), Query Frame = 3
Query: 6153 DLFFKLYFKAVSKICAWNQEYPVHSVSHIRTKILEPAMGVFGK-SLKQESDMLSTMSTFSYQQYTHINQYMRSSEYENRVKILTESKRDVSYLVDLRGKCPLRKILEKQSEVDWDELNNLSQDRERFLLSAAISCSECLQNEDGNDFKIFHLMSMWLSNESNE------KLNNIISDVIGKIETHKFLVLMPQLCARLNS--ENNKSFEINLEKLIKRIILDHPFHSIYNLLAIRNA---------------NRDXXXXXXXXXXXXXXANDKMNSRISVAYTMVEQLVKESQSDIIRDADILTTAYIHWANVDMSAFKQDIHKKLKFPLNCSLLR-IAKQVK-------------LPVPTLSIPIDRSLKYSLDRLPLIVGFDDVYSLQGGINLPKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNKG---------SITYKANSIK-SSDWSAFIYNRMISIRTYKVIPMTQTSGIIEWCEDTVPLGDWLANDKTGAHQRYRPQDSTPLQCRKRLQISAEENIKKRIETFKDILTKIQPVLGYFHFEKFPESQRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAFDLGKLMPTQERVPFRLTRDLVHGLGPFGVEGRFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLHSWKLNPQHARVLHTKREADNDCXXXXXXXXXXIEGFDNKSR-----------------PGSSQ-------------NQMAERVILEMSRKFAGAVDSSYL--------NCE---------GHVNYLIQTASNVENLARMFHGWQAYL 8351
D + Y ++ +C W E S + + + PA+ + + L +++ ++ FS Q+T +N Y+ SSE+ R LT++++DV L DL K L ++L++QS ++ DEL L+ D + FL ++ + ++CL D ++ IF +S+WLS+ +++ K+N I+S+ + I KFL L+PQL RL+S + + SF+ L KLI+R++ HP HS + LL + NA + K+ + +++ +++ RI A + +L + +++ L AY+ WAN D+ +K + + P +C L ++ +K + +PT + PIDRS Y L + GF + L GGINLPK++ C +DG RQLVK DD RQD+VMQQVF N LL G S T + N +K ++W + I IRTYKVIPM Q SG+IEWCEDTVPLGDWLAN++TGAHQRYRP+D P+Q ++RL + ++ +++ F +I K++PVL YF E+FP + WF +R +Y S+A+ S+VG+++GLGDRH N+LL +T E+IHID G+AFD G+L+PT E VPFRLTRDLVH LGP G++ F VL LR+ D+ILTL++VLL DPL+SW L+P L KR N + + ++S + + N ++ P + Q NQ+AERV+L + K G V + + NC GH+ L++ A++ NL+RM+ GWQAYL
Sbjct: 1640 DGYINCYIHGITVLCNWLYESRTKSAADLLLNYINPAINLAQRLKLNPDANAFMCLAKFSDAQFTTLNSYLTSSEFATRQNFLTQAQKDVIVLSDLGEKSRLLRLLQRQSALEIDELTALTTDADHFLEASIDAYAQCLSLSDDHNLSIFRFISLWLSSINSKFPNRASKMNKIMSERLPSIRADKFLPLVPQLAVRLSSKCDADSSFQNILMKLIERMVDWHPHHSAFTLLFLVNAKLDDDNNDNDGSRQRSTRVNSLKASTETIPNQSSTELSCRIQAAQQLYNRLSIGRRKELLYQMKYLAEAYVDWANTDVDKYKTNA-GNISLPNSCKLYGLVSPSLKRSSSRTMDCLLELVALPTCTFPIDRSGTYPNSSLIRVGGFSPDFRLVGGINLPKVIGCLGTDGKLYRQLVKGKDDPRQDAVMQQVFIAANCLLTKYGKSNKIDLPHSSTSQVNILKYRANW--LDMDNGIRIRTYKVIPMAQRSGVIEWCEDTVPLGDWLANERTGAHQRYRPRDMPPIQAKQRLGVVKDKTPDRKLVAFNEICEKLKPVLAYFFLEQFPNPKNWFVSRMAYIRSIAVTSVVGYLVGLGDRHPHNLLLHKSTGEIIHIDLGVAFDQGRLLPTPEMVPFRLTRDLVHALGPLGLQTGFIPAAETVLRELRNGSDVILTLLQVLLFDPLYSWSLSPAQLYALEAKRAEINTLDKSKSSSHFFNDHYRNTNKENFKMNTLQPNENSLIFPSNQQLYNTNMISENEPVNQLAERVLLGVKGKLQGLVSGNLVVNSNETSSNCSGGLDQLDVAGHIGLLVRAATDYSNLSRMYFGWQAYL 2464
BLAST of Serine-protein kinase ATM vs. Ensembl Cavefish
Match: atm (ATM serine/threonine kinase [Source:ZFIN;Acc:ZDB-GENE-040809-1]) HSP 1 Score: 483.411 bits (1243), Expect = 9.010e-137 Identity = 280/741 (37.79%), Postives = 433/741 (58.43%), Query Frame = 3
Query: 6189 KIC-AWNQEYPVHSVSHIRTKILEPAMGVF-----GKSLKQESDMLS---TMSTFSYQQYTHINQYMRSSEYENRVKILTESKRDVSYLVDLRGKCPLRKILEKQSEVDWD--ELNNLSQDRERFLLSAAISCSECLQNEDGNDFKIFHLMSMWLSNESNEKLNNIISDVIGKIETHKFLVLMPQLCAR-------LNSENNKSFEINLEKLIKRIILDHPFHSIYNLLAIRNANRDXXXXXXXXXXXXXXANDKMN-SRISVAYTMVEQLVKESQSDIIRDADILTTAYIHWANVDMSAFKQDIHKKLKFPLNCSLLRIAKQVKLPVPTLSIPIDRSLKYSLDRLPLIVGFDDVYSLQGGINLPKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKVIPMTQTSGIIEWCEDTVPLGDWLANDKTGAHQRYRPQDSTPLQCRKRLQISAEENIKKRIETFKDILTKIQPVLGYFHFEKFPESQRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAFDLGKLMPTQERVPFRLTRDLVHGLGPFGVEGRFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLHSWKLNPQHARVLHTKREADNDCXXXXXXXXXXIEG-FDNKSRPGSSQNQMAERVILEMSRKFAGAVDSSYLNCEGHVNYLIQTASNVENLARMFHGWQAYL 8351
++C +W E + S + I LE A+ F KQ+S M +++ FS QY I YMRSSE+EN+ +L ++K +V L+ R R ++ Q E++ D L NL DR RFLL A + CL+ + +D IF L S+WL N + +N+++ + + KI ++KFL LM QL AR L ++ F L +LI R +DHP H+++ +LA+ NAN+D +S+ ++ ++ R VA ++ ++++ ++ +I+ + L +AYI A +D S K + K + P + +++I + +PT+ I +D S KY + L I F + L GG+NLPKI+ C SDG RRQLVK DDLRQD+VMQQVF + ++LL +A R ++IR YKV+P +Q SG++EWC TVP+G++L + + GAH+R+RPQD T L CRK++ + K+++ F ++ +PV YF E+F + W + R +Y S+A +SIVG+I+GLGDRH+QNIL+D TAEL+HID G+AF+ GK++PT E VPFRL+RD+V G+G GVEG F+ C + ++RS ++++LT++EVLL+DPL W +NP A L +++ + N T N + E KS S N++AERV+L + K G + + L+ G VN LIQ A + +NL+R+F GWQA++
Sbjct: 2337 RLCGSWLSETCLESPAVILESYLERAVEAFEDHGGAPDPKQQSQMTQAFLSLARFSDAQYQGIENYMRSSEFENKQALLEKAKEEVD-LMKERNVTNNRYTVKVQRELELDVRALANLRADRRRFLLKAVENYIRCLELGEEHDTWIFRLASLWLENADVKNVNDMMKEGVKKIPSYKFLPLMYQLAARMGTKLSNLPTQEEAGFHSVLNELICRASMDHPHHTLFIILALVNANKDESFSRSRLSRNSARQPSPLDLERAEVAQKII-NVIRKQKAQMIQGIETLCSAYITLAYMDASRHKTE-KKAIPIPADQPIMKIKDLDNVIIPTMDIKVDPSGKY--EDLVTISSFKPHFHLAGGVNLPKIIDCVGSDGKSRRQLVKGQDDLRQDAVMQQVFHMCSTLLQR----------------NAETRKRKLNIRRYKVVPFSQRSGVLEWCSGTVPIGEFLVDPQKGAHKRFRPQDWTSLACRKKMMEAQRMEFDKKLQAFTEVCQNFRPVFRYFCMERFLDPAVWLEKRLAYTRSVATSSIVGYIVGLGDRHIQNILIDEQTAELVHIDLGVAFEQGKILPTPETVPFRLSRDIVDGMGITGVEGVFRRCCEKTMEVMRSSQEVLLTIVEVLLYDPLFDWTMNPLKAFHLQQQQDEQAELNATLNPTPAGEEPEAHRKSSDSQSFNKVAERVLLRLQEKLKGVEEGAVLSVGGQVNLLIQQAMDPKNLSRLFPGWQAWV 3056
BLAST of Serine-protein kinase ATM vs. Ensembl Cavefish
Match: atm (ATM serine/threonine kinase [Source:ZFIN;Acc:ZDB-GENE-040809-1]) HSP 1 Score: 482.256 bits (1240), Expect = 2.047e-136 Identity = 280/741 (37.79%), Postives = 433/741 (58.43%), Query Frame = 3
Query: 6189 KIC-AWNQEYPVHSVSHIRTKILEPAMGVF-----GKSLKQESDMLS---TMSTFSYQQYTHINQYMRSSEYENRVKILTESKRDVSYLVDLRGKCPLRKILEKQSEVDWD--ELNNLSQDRERFLLSAAISCSECLQNEDGNDFKIFHLMSMWLSNESNEKLNNIISDVIGKIETHKFLVLMPQLCAR-------LNSENNKSFEINLEKLIKRIILDHPFHSIYNLLAIRNANRDXXXXXXXXXXXXXXANDKMN-SRISVAYTMVEQLVKESQSDIIRDADILTTAYIHWANVDMSAFKQDIHKKLKFPLNCSLLRIAKQVKLPVPTLSIPIDRSLKYSLDRLPLIVGFDDVYSLQGGINLPKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKVIPMTQTSGIIEWCEDTVPLGDWLANDKTGAHQRYRPQDSTPLQCRKRLQISAEENIKKRIETFKDILTKIQPVLGYFHFEKFPESQRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAFDLGKLMPTQERVPFRLTRDLVHGLGPFGVEGRFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLHSWKLNPQHARVLHTKREADNDCXXXXXXXXXXIEG-FDNKSRPGSSQNQMAERVILEMSRKFAGAVDSSYLNCEGHVNYLIQTASNVENLARMFHGWQAYL 8351
++C +W E + S + I LE A+ F KQ+S M +++ FS QY I YMRSSE+EN+ +L ++K +V L+ R R ++ Q E++ D L NL DR RFLL A + CL+ + +D IF L S+WL N + +N+++ + + KI ++KFL LM QL AR L ++ F L +LI R +DHP H+++ +LA+ NAN+D +S+ ++ ++ R VA ++ ++++ ++ +I+ + L +AYI A +D S K + K + P + +++I + +PT+ I +D S KY + L I F + L GG+NLPKI+ C SDG RRQLVK DDLRQD+VMQQVF + ++LL +A R ++IR YKV+P +Q SG++EWC TVP+G++L + + GAH+R+RPQD T L CRK++ + K+++ F ++ +PV YF E+F + W + R +Y S+A +SIVG+I+GLGDRH+QNIL+D TAEL+HID G+AF+ GK++PT E VPFRL+RD+V G+G GVEG F+ C + ++RS ++++LT++EVLL+DPL W +NP A L +++ + N T N + E KS S N++AERV+L + K G + + L+ G VN LIQ A + +NL+R+F GWQA++
Sbjct: 2311 RLCGSWLSETCLESPAVILESYLERAVEAFEDHGGAPDPKQQSQMTQAFLSLARFSDAQYQGIENYMRSSEFENKQALLEKAKEEVD-LMKERNVTNNRYTVKVQRELELDVRALANLRADRRRFLLKAVENYIRCLELGEEHDTWIFRLASLWLENADVKNVNDMMKEGVKKIPSYKFLPLMYQLAARMGTKLSNLPTQEEAGFHSVLNELICRASMDHPHHTLFIILALVNANKDESFSRSRLSRNSARQPSPLDLERAEVAQKII-NVIRKQKAQMIQGIETLCSAYITLAYMDASRHKTE-KKAIPIPADQPIMKIKDLDNVIIPTMDIKVDPSGKY--EDLVTISSFKPHFHLAGGVNLPKIIDCVGSDGKSRRQLVKGQDDLRQDAVMQQVFHMCSTLLQR----------------NAETRKRKLNIRRYKVVPFSQRSGVLEWCSGTVPIGEFLVDPQKGAHKRFRPQDWTSLACRKKMMEAQRMEFDKKLQAFTEVCQNFRPVFRYFCMERFLDPAVWLEKRLAYTRSVATSSIVGYIVGLGDRHIQNILIDEQTAELVHIDLGVAFEQGKILPTPETVPFRLSRDIVDGMGITGVEGVFRRCCEKTMEVMRSSQEVLLTIVEVLLYDPLFDWTMNPLKAFHLQQQQDEQAELNATLNPTPAGEEPEAHRKSSDSQSFNKVAERVLLRLQEKLKGVEEGAVLSVGGQVNLLIQQAMDPKNLSRLFPGWQAWV 3030
BLAST of Serine-protein kinase ATM vs. Ensembl Cavefish
Match: atr (ATR serine/threonine kinase [Source:ZFIN;Acc:ZDB-GENE-070912-458]) HSP 1 Score: 205.297 bits (521), Expect = 4.430e-52 Identity = 154/589 (26.15%), Postives = 271/589 (46.01%), Query Frame = 3
Query: 6639 KLNNIISDVIGKIETHKFLVLMPQLCARLNSENNKSFEINLEKLIKRIILDHPFHSIYNLLAIRNANRDXXXXXXXXXXXXXXANDKMNSRISVAYTMVEQLVKESQSDIIRDADILTTAYIHWANVDMSAFKQDIHKKLKFPLNCSLLRIAK--QVKLPVPTLSIPIDRSLKYS---LDRLP----LIVGFDDVYSLQGGINLPKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKVIPMTQTSGIIEWCEDTVPLGDWLANDKTGAHQRYRPQDS--TPLQCRKRLQISAEENIKKRIETFKDIL-TKIQPVLGYFHFEKFPESQRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAFDLGKLMPTQERVPFRLTRDLVHGLGPFGVEGRFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLHSWKLNPQHARVLHTKREADNDCXXXXXXXXXXIEGFDNKSRPGSSQNQMAERVILEMSRKFAGAVDSS------YLNCEGHVNYLIQTASNVENLARMFHGWQAYL 8351
K+N +IS+ + ++FL QL +R+ ++ F + L + ++ L +P +++ + A+ ++ + +MN + V +K S I DA+ LT + N + + + F L L+ + ++ +P+ ++ IP S + D P + GFDD + + PK + + SDG + K DDLR+D + + ++N L A R + IRTY VIP+ + GIIEW +T L L ++ Y+ + T + RK + + +++++++ KD+L + PV + FP+ W+ +R +Y S A+ S+VG++LGLGDRH +NIL D T E +H+DF F+ G+ E VPFRLT+++VH +GP G EG F+ C L L+R Q++ ++++++ LHDPL W P + K +A+ G N+ A+ + ++ ++ G + + L+ EGHV+YLIQ A++ L +M+ GW YL
Sbjct: 1915 KINAVISEHTSNLSPYQFLTAFSQLISRVCHSSDDVFSV-LMDIAAKVFLAYPQQAMWMMTAVSKSSYPT----------------RMNRCKEILKKAVS--LKSSFGKFIEDANRLTDKLVELCNKPVDGNSSTLSMSVHFKLLKRLVEESSFSEILIPLQSVLIPTLPSTGGANPHHDAFPGHWVYLSGFDDSVEILASLQKPKKISLRGSDGKFYTMMCKPKDDLRKDCRLMEFNCLINKCLRK----------------DAESRRRDLHIRTYAVIPLNEECGIIEWVNNTAGLRHIL-------NKLYKEKGIYLTGKELRKMI-LPKTASLQEKLKLHKDVLCARHPPVFHDWFLRTFPDPTSWYNSRSAYCRSTAVMSMVGYVLGLGDRHGENILFDSLTGECVHVDFNCLFNKGETFDVPEVVPFRLTQNMVHAMGPMGTEGLFRQACEVTLRLMRDQREPLMSVLKTFLHDPLVEWS-KPVKGSL---KTQANES---------------------GEIVNEKAKTHVQDIEQRLQGVIKNRNKVMGLPLSIEGHVHYLIQEATDDNLLCQMYLGWGPYL 2435
BLAST of Serine-protein kinase ATM vs. Ensembl Cavefish
Match: mtor (mechanistic target of rapamycin kinase [Source:NCBI gene;Acc:103042377]) HSP 1 Score: 157.918 bits (398), Expect = 1.001e-37 Identity = 123/412 (29.85%), Postives = 203/412 (49.27%), Query Frame = 3
Query: 7224 PKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKVIPMTQTSGIIEWCEDTVPLGDWLANDKTGAHQRYRPQDSTPLQCRKRLQISAEENIKKRIETFKDILTKIQPVLGYFH--------------FEKFPESQRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAFDLGKLMPT-QERVPFRLTRDLVHGLGPFGVEGRFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLHSWKLNPQHARVLHTKREADNDCXXXXXXXXXXIEGFD----NKSRPGSS------------------QNQMAERVILEMSRKFAGAVDSSY---LNCEGHVNYLIQTASNVENLARMFHGW 8339
P+ + S+G + L+K ++DLRQD + Q+F +VN+LL N + K +SI+ Y VIP++ SG+I W VP D L + YR +K++ ++ E I R+ D LT ++ V + H + K P S+ WF R +Y SLA+ S+VG+ILGLGDRH N++LD + +++HIDFG F++ E++PFRLTR L + + G++G ++ TC V+ +LR +D ++ ++E ++DPL +W+L + + TKR + T+ S +T+EG D +PG++ N+ A ++I + K G D S+ L+ V LI+ A++ ENL + + GW
Sbjct: 2138 PRKLTIMGSNGHEFMFLLKGHEDLRQDERVMQLFGLVNTLLANDPASLRKN----------------LSIQRYAVIPLSTNSGLIGW----VPHCDTLH----ALIRDYRE--------KKKILLNIEHRIMLRMAPDYDHLTLMEKVEVFEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRITCHTVMEVLREHRDSVMAVLEAFVYDPLLNWRLMDTNTK--GTKRSRTRTDSYTAGQSVETMEGIDLGETTHKKPGTTVPESIHSFIGDGLVQPEALNKKAIQIINRVRDKLTGR-DFSHDETLDVPTQVELLIKQATSHENLCQCYIGW 2514
BLAST of Serine-protein kinase ATM vs. Ensembl Cavefish
Match: smg1 (SMG1 nonsense mediated mRNA decay associated PI3K related kinase [Source:ZFIN;Acc:ZDB-GENE-061013-767]) HSP 1 Score: 140.198 bits (352), Expect = 2.499e-32 Identity = 94/337 (27.89%), Postives = 156/337 (46.29%), Query Frame = 3
Query: 7224 PKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKVIPMTQTSGIIEWCEDTVPL----GDWLANDKT----GAHQRYRPQDSTPLQCRKR-----------LQISAEENIKKR---IETFKDILTKIQP-----VLGYFHFEKFPESQRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAFDLGKLMPTQERVPFRLTRDLVHGLGPFGVEGRFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLHSWKL-------------NPQHARVLHTKREADND 8114
PK ++ SDG L K +DL D + Q S+VN++ K N +S + A R Y V P+ SG+I+W + PL W + A Y+ + P+ R + ++ +R + +D+L ++ +L + W++ +SYA S A+ S+VG+I+GLGDRH+ N+L+D+ T E++HID+ + F+ GK + E+VPFR+T ++ LG GVEG F+ +C V+ ++R ++ +LTL+E ++DPL W Q A +KRE + D
Sbjct: 2121 PKKLYFLGSDGKNYPYLFKGLEDLHLDERIMQFLSIVNTMFT-------KVNQQESPRFHA---------RHYSVTPLGTRSGLIQWVDGATPLFGLYKRWQQREAVLQAQKAQDSYQQPQNLPMVPRPSELYYSKIGPALKAVGLSLDVSRRDWPLSVMRDVLRELMEATPPNLLAKELWCSCTTPSEWWRVTQSYARSTAVMSMVGYIIGLGDRHLDNVLIDMTTGEVVHIDYNVCFEKGKSLRVPEKVPFRMTHNIETALGVTGVEGIFRLSCEQVVQMMRRGRETLLTLLEAFVYDPLVDWTAGGEVGFAGAVYGGGGQQAESKQSKREMERD 2441
BLAST of Serine-protein kinase ATM vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007186.1 (pep scaffold:Pmarinus_7.0:GL476459:175296:202639:-1 gene:ENSPMAG00000006485.1 transcript:ENSPMAT00000007186.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 489.574 bits (1259), Expect = 2.454e-147 Identity = 278/769 (36.15%), Postives = 443/769 (57.61%), Query Frame = 3
Query: 6159 FFKLYFKAVSKICAWNQEYPVHSVSHIRTKILEPAMGVFGKSLKQ--------------ESDMLSTMSTFSYQQYTHINQYMRSSEYENRVKILTESKRDVSYLVDLRGKCPLRKILEKQSEVDWDE--LNNLSQDRERFLLSAAISCSECLQNEDGN-DFKIFHLMSMWLSNESNEKLNNIISDVIGKIETHKFLVLMPQLCARLNSE--NNKSFEINLEKLIKRIILDHPFHSIYNLLAIRNANRDXXXXXXXXXXXXXXA-----NDKMNS-------RISVAYTMVEQLVKESQSDIIRDADILTTAYIHWANVDMSAFKQDIHKKLKFPLNCSLLRIAKQVKLPVPTLSIPIDRSLKYSLDRLPLIVGFDDVYSLQGGINLPKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKVIPMTQTSGIIEWCEDTVPLGDWLANDKTGAHQRYRPQDSTPLQCRKRLQISAEENIKKRI-ETFKDILTKIQPVLGYFHFEKFPESQRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAFDLGKLMPTQERVPFRLTRDLVHGLGPFGVEGRFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLHSWKLNPQHARVLHTKREADNDCXXXXXXXXXXIEGFD---NKSRPG---SSQNQMAERVILEMSRKFAGAVDSSYLNCEGHVNYLIQTASNVENLARMFHGWQAYL 8351
LY + + + W E S S I ++ LE ++ V ++ + + +++ F+ Q+ I YMRS+EYEN+ +L ++K DV+ L L+ + P R +++ Q E D DE L +L QDRERFL+ A ++ CL++ + + + F L+S+WL N + +++N+++ + I HKFL L+ QL AR+ ++ ++F L+KLI R+ L HP H++ +LA+ NA +D L+ + + D S R+ +VEQ V++ Q +++RD + L AYI AN++ A+++ K + P + + I K+ +PTL + +D + +Y L + F + L GG+NLPKI+ C+ SDG RQLVK DDLRQD+VMQQVF + N LL SA R +SIRTYKV+P++Q SG++EWC T+P+GD+L TGAH +YRP D + CRK + ++A++ + ++++ +PV +F +E+F + WF+ R SY S+A +SIVG+I+GLGDRHVQNIL+D+N+AEL+HID G+AF+ G+++PT E VPFRLTRD+V G+G GVEG F+ C + ++R+ ++ +LT++EVLL DPL W +NP A L T+ E + + +T + ++ R G S N+MAERV++ + +K G + S L+ G VN LIQ A++ +NL+R+F GWQ ++
Sbjct: 355 LLALYAECLGRYGHWLAETCSESPSIILSEYLEKSVSVAERAWGDGSGGSDEGEGGRVCRAALYLSLARFADAQHRSIVAYMRSAEYENKRALLRKAKEDVTLLQSLKLQ-PSRYMVKLQRECDLDERELLSLRQDRERFLVEALVNYVRCLRSGGAHGEARAFRLVSLWLENSAEQQVNDVMRTGVTDIPPHKFLPLIYQLAARMGTKMAGGEAFHSILQKLILRVTLTHPHHALLVVLALANAGKDELLQTVAARDGARGGSRLSRGDSKGSSAPSDDDRVRATRALVEQ-VRKQQPELVRDTEKLCDAYIMLANMNAEAWRKQT-KDMLIPKDQPIKEIRNLYKVVIPTLELKVDPTGQYP--DLVTVRAFRPHFRLAGGVNLPKIIDCEGSDGRTYRQLVKGRDDLRQDAVMQQVFHMCNELLAG----------------SAETRTRKLSIRTYKVVPLSQRSGVLEWCVGTMPIGDYLVQKDTGAHTKYRPNDWPSMHCRKFMNVAAQDRRNGDLFLAYQELCHHFRPVFRHFFWERFLDPAVWFERRLSYTRSVATSSIVGYIVGLGDRHVQNILIDLNSAELVHIDLGVAFEQGRILPTPETVPFRLTRDIVDGMGITGVEGVFRRCCEKTMEVMRNSQEALLTIVEVLLFDPLFDWTMNPLKALTLQTRTEDETEGTSTMGPTLGKAPASGRAVHQERNGMDPQSLNKMAERVLMRLQQKLKGVEEGSVLSVPGQVNLLIQQATDPKNLSRLFPGWQPWV 1102
BLAST of Serine-protein kinase ATM vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003429.1 (pep scaffold:Pmarinus_7.0:GL476508:503342:564700:-1 gene:ENSPMAG00000003096.1 transcript:ENSPMAT00000003429.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 183.341 bits (464), Expect = 4.662e-46 Identity = 146/600 (24.33%), Postives = 262/600 (43.67%), Query Frame = 3
Query: 6639 KLNNIISDVIGKIETHKFLVLMPQLCARLNSENNKSFEINLEKLIKRIILDHPFHSIYNLLAIRNANRDXXXXXXXXXXXXXXANDKMNSRISVAYTMVEQLVKESQSDIIRDADILTTAYIHWANVDMSAFKQDIHKKLKFPLNCSLLRIAKQVK-LPVPTLSIPIDRSLKYSLDRLP--------------LIVGFDDVYSLQGGINLPKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKVIPMTQTSGIIEWCEDTVPLG---DWLANDK-TGAHQRYRPQDSTPLQCRKRLQISAEENIKKRIETFKD-ILTKIQPVLGYFHFEKFPESQRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAFDLGKLMPTQERVPFRLTRDLVHGLGPFGVEGRFKTTCCDVLNLLRSQKDIIL---TLIEVLLHDPLHSWKLNPQHARVLHTKREADNDCXXXXXXXXXXIEGFDNKSRPGSSQNQMAERVILEMSRKFAGAVDSS-------YLNCEGHVNYLIQTASNVENLARMFHGWQAY 8348
K+ I+++ K+ ++FL QL +R+ + + L+ +I +++ +P +++ ++A+ ++ + R + Q V S IRD LT + N K + K+ +N + + + V + IP+ + +L P IVGF D + + PK + + SDG + K DDLR+D + + S++N L K + + + R + I TY VIP+ + G++EW +T L D L N+K G + P+ E +++++ ++D +L PV + FP+ W+ +R Y S A+ S+VG++LGLGDRH +NIL D T E +H+DF F+ G E VPFRLT ++VH +GP G+EG F+ C + ++ Q++ ++ ++++ +HDPL W P H + EA G N+ A++++ ++ ++ G + + L+ EGHV+YLIQ A+N + L +M+ GW +
Sbjct: 2115 KIIKIMTEHTQKLAPYQFLTAFSQLISRI-CHPHAAVCAALQAIIVKVLTRYPQQALWMMMAVSKSS-----------------HAARAERCKAIFGKAVQ-VDGSLRKFIRDGTSLTDLLLELCN------KPTMDKQTTMSMNVNFRGLKRLVDDTNFSNVLIPLQAVMTPTLPSTPGGHADHDPFPGNMAYIVGFHDPVEVLSSLQKPKKICIRGSDGRSYPMMCKPKDDLRKDCRLMEFNSLINKDLLRKDAESRR---------------RDLRICTYAVIPLNEECGLVEWVNNTESLRTIVDILYNEKGIGLTMSEVSKCILPI----------ETPLEQKLSMYRDKLLPPHPPVFHEWFLRTFPDPTSWYSSRLGYTRSTAVMSMVGYVLGLGDRHGENILFDSLTGECMHVDFNCLFNKGLTFGVPELVPFRLTHNMVHAMGPMGLEGLFRRACEVTMRVMCDQRESLIRGASVLKTFIHDPLVEWS-RPLHGSWRGSANEA------------------------GEVVNEKAKQIVQDIEQRLHGVIKNPNNRVRGLPLSIEGHVHYLIQEATNEKLLCQMYLGWAPF 2639
BLAST of Serine-protein kinase ATM vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003412.1 (pep scaffold:Pmarinus_7.0:GL476508:503342:564700:-1 gene:ENSPMAG00000003096.1 transcript:ENSPMAT00000003412.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 182.956 bits (463), Expect = 5.365e-46 Identity = 146/600 (24.33%), Postives = 262/600 (43.67%), Query Frame = 3
Query: 6639 KLNNIISDVIGKIETHKFLVLMPQLCARLNSENNKSFEINLEKLIKRIILDHPFHSIYNLLAIRNANRDXXXXXXXXXXXXXXANDKMNSRISVAYTMVEQLVKESQSDIIRDADILTTAYIHWANVDMSAFKQDIHKKLKFPLNCSLLRIAKQVK-LPVPTLSIPIDRSLKYSLDRLP--------------LIVGFDDVYSLQGGINLPKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKVIPMTQTSGIIEWCEDTVPLG---DWLANDK-TGAHQRYRPQDSTPLQCRKRLQISAEENIKKRIETFKD-ILTKIQPVLGYFHFEKFPESQRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAFDLGKLMPTQERVPFRLTRDLVHGLGPFGVEGRFKTTCCDVLNLLRSQKDIIL---TLIEVLLHDPLHSWKLNPQHARVLHTKREADNDCXXXXXXXXXXIEGFDNKSRPGSSQNQMAERVILEMSRKFAGAVDSS-------YLNCEGHVNYLIQTASNVENLARMFHGWQAY 8348
K+ I+++ K+ ++FL QL +R+ + + L+ +I +++ +P +++ ++A+ ++ + R + Q V S IRD LT + N K + K+ +N + + + V + IP+ + +L P IVGF D + + PK + + SDG + K DDLR+D + + S++N L K + + + R + I TY VIP+ + G++EW +T L D L N+K G + P+ E +++++ ++D +L PV + FP+ W+ +R Y S A+ S+VG++LGLGDRH +NIL D T E +H+DF F+ G E VPFRLT ++VH +GP G+EG F+ C + ++ Q++ ++ ++++ +HDPL W P H + EA G N+ A++++ ++ ++ G + + L+ EGHV+YLIQ A+N + L +M+ GW +
Sbjct: 2149 KIIKIMTEHTQKLAPYQFLTAFSQLISRI-CHPHAAVCAALQAIIVKVLTRYPQQALWMMMAVSKSS-----------------HAARAERCKAIFGKAVQ-VDGSLRKFIRDGTSLTDLLLELCN------KPTMDKQTTMSMNVNFRGLKRLVDDTNFSNVLIPLQAVMTPTLPSTPGGHADHDPFPGNMAYIVGFHDPVEVLSSLQKPKKICIRGSDGRSYPMMCKPKDDLRKDCRLMEFNSLINKDLLRKDAESRR---------------RDLRICTYAVIPLNEECGLVEWVNNTESLRTIVDILYNEKGIGLTMSEVSKCILPI----------ETPLEQKLSMYRDKLLPPHPPVFHEWFLRTFPDPTSWYSSRLGYTRSTAVMSMVGYVLGLGDRHGENILFDSLTGECMHVDFNCLFNKGLTFGVPELVPFRLTHNMVHAMGPMGLEGLFRRACEVTMRVMCDQRESLIRGASVLKTFIHDPLVEWS-RPLHGSWRGSANEA------------------------GEVVNEKAKQIVQDIEQRLHGVIKNPNNRVRGLPLSIEGHVHYLIQEATNEKLLCQMYLGWAPF 2673
BLAST of Serine-protein kinase ATM vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003421.1 (pep scaffold:Pmarinus_7.0:GL476508:503342:564700:-1 gene:ENSPMAG00000003096.1 transcript:ENSPMAT00000003421.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 182.956 bits (463), Expect = 6.548e-46 Identity = 146/600 (24.33%), Postives = 262/600 (43.67%), Query Frame = 3
Query: 6639 KLNNIISDVIGKIETHKFLVLMPQLCARLNSENNKSFEINLEKLIKRIILDHPFHSIYNLLAIRNANRDXXXXXXXXXXXXXXANDKMNSRISVAYTMVEQLVKESQSDIIRDADILTTAYIHWANVDMSAFKQDIHKKLKFPLNCSLLRIAKQVK-LPVPTLSIPIDRSLKYSLDRLP--------------LIVGFDDVYSLQGGINLPKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKVIPMTQTSGIIEWCEDTVPLG---DWLANDK-TGAHQRYRPQDSTPLQCRKRLQISAEENIKKRIETFKD-ILTKIQPVLGYFHFEKFPESQRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAFDLGKLMPTQERVPFRLTRDLVHGLGPFGVEGRFKTTCCDVLNLLRSQKDIIL---TLIEVLLHDPLHSWKLNPQHARVLHTKREADNDCXXXXXXXXXXIEGFDNKSRPGSSQNQMAERVILEMSRKFAGAVDSS-------YLNCEGHVNYLIQTASNVENLARMFHGWQAY 8348
K+ I+++ K+ ++FL QL +R+ + + L+ +I +++ +P +++ ++A+ ++ + R + Q V S IRD LT + N K + K+ +N + + + V + IP+ + +L P IVGF D + + PK + + SDG + K DDLR+D + + S++N L K + + + R + I TY VIP+ + G++EW +T L D L N+K G + P+ E +++++ ++D +L PV + FP+ W+ +R Y S A+ S+VG++LGLGDRH +NIL D T E +H+DF F+ G E VPFRLT ++VH +GP G+EG F+ C + ++ Q++ ++ ++++ +HDPL W P H + EA G N+ A++++ ++ ++ G + + L+ EGHV+YLIQ A+N + L +M+ GW +
Sbjct: 2135 KIIKIMTEHTQKLAPYQFLTAFSQLISRI-CHPHAAVCAALQAIIVKVLTRYPQQALWMMMAVSKSS-----------------HAARAERCKAIFGKAVQ-VDGSLRKFIRDGTSLTDLLLELCN------KPTMDKQTTMSMNVNFRGLKRLVDDTNFSNVLIPLQAVMTPTLPSTPGGHADHDPFPGNMAYIVGFHDPVEVLSSLQKPKKICIRGSDGRSYPMMCKPKDDLRKDCRLMEFNSLINKDLLRKDAESRR---------------RDLRICTYAVIPLNEECGLVEWVNNTESLRTIVDILYNEKGIGLTMSEVSKCILPI----------ETPLEQKLSMYRDKLLPPHPPVFHEWFLRTFPDPTSWYSSRLGYTRSTAVMSMVGYVLGLGDRHGENILFDSLTGECMHVDFNCLFNKGLTFGVPELVPFRLTHNMVHAMGPMGLEGLFRRACEVTMRVMCDQRESLIRGASVLKTFIHDPLVEWS-RPLHGSWRGSANEA------------------------GEVVNEKAKQIVQDIEQRLHGVIKNPNNRVRGLPLSIEGHVHYLIQEATNEKLLCQMYLGWAPF 2659
BLAST of Serine-protein kinase ATM vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010422.1 (pep scaffold:Pmarinus_7.0:GL478779:2292:46075:1 gene:ENSPMAG00000009431.1 transcript:ENSPMAT00000010422.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 65.4698 bits (158), Expect = 2.142e-10 Identity = 63/258 (24.42%), Postives = 106/258 (41.09%), Query Frame = 3
Query: 7287 DDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKVIPMTQTSGIIEWCEDTVPLGDWLANDKTGAHQRYRPQDSTPLQCRKRLQISAEENIKKRIETFKDILTKIQPVLGYFHFEKFPESQ-RWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAFDLGKLMPTQERVPFRLTRDLVHGLGPFGVEGRFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLHSW 8057
+DL D + Q S+VN++ K N +W F R Y V P+ SG+I+W + PL G ++R++ +R ++A + E P S+ R RK N L RH++ V++ + + + AF++ E+VPFR+T+D+ LG GVEG F+ +C +L ++R ++ +LTL+E ++DPL W
Sbjct: 2110 EDLHLDERIMQFLSIVNNMF-------VKGNG---REWHRF------HARHYSVTPLGSRSGLIQWVDGATPL--------FGLYKRWQ----------QRETLTAGHKV-----------------------ELVPCSRIRLADPRKQIKNFL--------------RHLREC--AVSSFKSVRVTKARAFEV------PEKVPFRMTQDIERALGVTGVEGIFRLSCEQILQIMRRGRETLLTLLEAFVYDPLVDW 2288
BLAST of Serine-protein kinase ATM vs. Ensembl Yeast
Match: TEL1 (Protein kinase primarily involved in telomere length regulation; contributes to cell cycle checkpoint control in response to DNA damage; acts with Red1p and Mec1p to promote interhomolog recombination by phosphorylation of Hop1; functionally redundant with Mec1p; regulates P-body formation induced by replication stress; homolog of human ataxia-telangiectasia mutated (ATM) gene [Source:SGD;Acc:S000000184]) HSP 1 Score: 271.552 bits (693), Expect = 4.468e-73 Identity = 194/606 (32.01%), Postives = 309/606 (50.99%), Query Frame = 3
Query: 6609 SMWLSNESNEKLNNIISDVIGKIETHKFLVLMPQLCARLNSENNKSFEINLEKLIKRIILDHPFHSIYNLLAI----RNANRDXXXXXXXXXXXXXXANDKMNSRISVAYTMVEQLVKESQSDIIRDADILTTAYIHWAN--VDMSAFKQDIHKKLKFPLNCSLLRIA---------KQV---KLPVPTLSIPIDRSLKYSLDRLPLIVGFDDVYSLQG-GINLPKIVWCQSSDGLKRRQLVK-SNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKVIPMTQTSGIIEWCEDTVPLGDWLANDKTGAHQRYRPQDSTPLQCRKRLQISAEENIKKRIETFKDILTKIQPVLGYFHFEKFPESQRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAFDLGKLMPTQERVPFRLTRDLVHGLGPFGVEGRFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLHSWKLNP--QHARVLHTKREADNDCXXXXXXXXXXIEGFDNKSRPGS----SQNQMAERVILEMSRKFAGAVDSSYLNCEGHVNYLIQTASNVENLARMFHGWQAY 8348
+W N+ N K+N ++ IG I + KFL + Q+ ++++ E N+ F+ L+ +KR++ P+ S+Y++++I + +N+D + IS V++++ E Q D Y+ +MS + LKF N LR+A KQ+ KLP+PT + + S R P IV ++ + G++LPKIV SDG ++ L+K SNDDLRQD++M+QVF VN +L N + N + IRTYKV+P+ +GIIE+ ++ L L+ T + Q RK ++ ++ ++R++ + I +I+P L F F+ FP+ WF+A+K+Y +A +SIVG+ILGLGDRH+ NILLD +T E IHID GIAFD GKL+P E VPFRLTRD+V G G GV+G F+ +C V +LR ++ ++ +L DPL+SW ++P ++ + + E N FDN S+ S ++NQ + R + + K G + L+ E V LIQ A++ NL+ ++ GW +
Sbjct: 2252 GLWFENDDNSKINQLLYKEIGTIPSWKFLPWVNQIASKISMEENE-FQKPLQLTMKRLLYKLPYDSLYSVMSILLYEKQSNKD--------------------TNISQKIQAVKKILLELQG---YDRGAFAKKYLLPVQEFCEMSVELAN----LKFVQNTKTLRLANLKIGQYWLKQLNMEKLPLPTSNFTVKSSADGRKAR-PYIVSVNETVGITTTGLSLPKIVTFNISDGTTQKALMKGSNDDLRQDAIMEQVFQQVNKVLQN----------------DKVLRNLDLGIRTYKVVPLGPKAGIIEFVANSTSLHQILSKLHTNDKITFD-------QARKGMKAVQTKSNEERLKAYLKITNEIKPQLRNFFFDSFPDPLDWFEAKKTYTKGVAASSIVGYILGLGDRHLNNILLDCSTGEPIHIDLGIAFDQGKLLPIPELVPFRLTRDIVDGFGVTGVDGLFRRSCERVYAVLRKDYVKVMCVLNILKWDPLYSWVMSPVKKYEHLFEEEHEITN---------------FDNVSKFISNNDRNENQESYRALKGVEEKLMG----NGLSVESSVQDLIQQATDPSNLSVIYMGWSPF 2786
BLAST of Serine-protein kinase ATM vs. Ensembl Yeast
Match: TOR2 (PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex that regulates growth in response to nutrients and TORC2, a complex that regulates cell-cycle dependent polarization of the actin cytoskeleton; involved in meiosis; TOR2 has a paralog, TOR1, that arose from the whole genome duplication [Source:SGD;Acc:S000001686]) HSP 1 Score: 160.614 bits (405), Expect = 2.040e-39 Identity = 116/405 (28.64%), Postives = 200/405 (49.38%), Query Frame = 3
Query: 7176 IVGFDDVYSLQGGINLPKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKVIPMTQTSGIIEWCEDTVPLGDWLANDKTGAH---QRYRPQDSTPLQCRK--RLQISAEEN---IKKRIETFKDILTKIQPVLGY-FHFEKFPESQRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAFDLGKLMPT-QERVPFRLTRDLVHGLGPFGVEGRFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLHSWKLNPQHARV-----LHTKREADNDCXXXXXXXXXXIEGFDNKSRPGSSQNQMAERVILEMSRKFAGAVDSSY--LNCEGHVNYLIQTASNVENLARMFHGW 8339
I F+ V+S+ P+ + SDG + ++K ++D+RQDS++ Q+F +VN+LL N A + R + I+ Y IP++ SG++ W VP D H + +R PL LQ++ + + + +++E F L + Y + K S+ W + R +Y SLA+ S+ G+ILGLGDRH N++LD T ++IHIDFG F+ L E+VPFRLTR L + + G+EG F+ TC +V+ +LR K ++ ++E DPL +W + ++ + N+ + + + ++ +N+ + + +N A V+ ++ K G + L+ V+ LIQ A++VENL + + GW
Sbjct: 2094 ISKFEPVFSVISSKQRPRKFCIKGSDGKDYKYVLKGHEDIRQDSLVMQLFGLVNTLLQN----------------DAECFRRHLDIQQYPAIPLSPKSGLLGW----VPNSDTF-------HVLIREHREAKKIPLNIEHWVMLQMAPDYDNLTLLQKVEVFTYALNNTEGQDLYKVLWLKSRSSETWLERRTTYTRSLAVMSMTGYILGLGDRHPSNLMLDRITGKVIHIDFGDCFEAAILREKFPEKVPFRLTRMLTYAMEVSGIEGSFRITCENVMKVLRDNKGSLMAILEAFAFDPLINWGFDLPTKKIEEETGIQLPVMNANELLSNGAITEEEVQRVENEHK-NAIRNARAMLVLKRITDKLTGNDIRRFNDLDVPEQVDKLIQQATSVENLCQHYIGW 2470
BLAST of Serine-protein kinase ATM vs. Ensembl Yeast
Match: MEC1 (Genome integrity checkpoint protein and PI kinase superfamily member; Mec1p and Dun1p function in same pathway to regulate dNTP pools and telomere length; signal transducer required for cell cycle arrest and transcriptional responses to damaged or unreplicated DNA; facilitates replication fork progression and regulates P-body formation under replication stress; promotes interhomolog recombination by phosphorylating Hop1p; associates with shortened, dysfunctional telomeres [Source:SGD;Acc:S000000340]) HSP 1 Score: 155.606 bits (392), Expect = 7.377e-38 Identity = 140/583 (24.01%), Postives = 253/583 (43.40%), Query Frame = 3
Query: 6624 NESNEKLNNIISDVIGKIETHKFLVLMPQLCARLNSENNKSFEINLEKLIKRIILDHPFHSIYNLLAIRNANRDXXXXXXXXXXXXXXANDKMNSRISVAYTMVEQLVKESQS--DIIRDADILTTAYIHWANVDMSAFK----QDIHKKLKFPLNCSLLRIAKQVKLPVPTLSIPIDRSLKYSLDRLPL--IVGFDDVYSLQGGINLPKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKVIPMTQTSGIIEWCEDTVPLGDWLANDKTGAHQRYRPQDSTPLQCRKRLQISAEENIKKRIETFKDILTKIQPVLGYFHFEKFPESQRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAFDLGKLMPTQERVPFRLTRDLVHGLGPFGVEGRFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLHSWKLNPQHARVLHTKREADNDCXXXXXXXXXXIEGFDNKSRPGSSQNQMAERVILEMSRKFAGAVDSSYLNCEGHVNYLIQTASNVENLARMFHGWQAY 8348
+++ E + + + + + T+ + ++ QL +RL + S +I + L+ + +++P H ++ + A+ N+N + R+ ++E+ + SQ+ D++ A LT A D+ + + + K KF +N + + V+ + +S S++ P+ I+ F Y + + PK + SDG + K +D+RQD+ Q + ++ LL S D ++ R + I Y V+ + + GI+E + V L L+ +Y + R Q +A + ++E + + + K P+L + E FP+ WF AR +YA S A+ ++VG ILGLGDRH +NILLD+ T +++H+DF F+ GK +P E VPFRLT +L+ LG G EG FK + L L+R + ++ +IE +++D R D+ I G D + D L+ G LIQ A++ +NL++M+ GW +
Sbjct: 1875 SKATEDICSHVEEALQHCPTYIWYFVLTQLLSRLLHSHQSSAQIIMHILLS-LAVEYPSHILWYITALVNSNS--------------------SKRVLRGKHILEKYRQHSQNPHDLVSSALDLTKALTRVCLQDVKSITSRSGKSLEKDFKFDMNVAPSAMVVPVRKNLDIISPLESNSMRGYQPFRPVVSIIRFGSSYKVFSSLKKPKQLNIIGSDGNIYGIMCKK-EDVRQDNQYMQFATTMDFLL--------------SKDIAS--RKRSLGINIYSVLSLREDCGILEMVPNVVTLRSILSTKYESLKIKYSLK-----SLHDRWQHTA---VDGKLEFYMEQVDKFPPILYQWFLENFPDPINWFNARNTYARSYAVMAMVGHILGLGDRHCENILLDIQTGKVLHVDFDCLFEKGKRLPVPEIVPFRLTPNLLDALGIIGTEGTFKKSSEVTLALMRKNEVALMNVIETIMYD------------------RNMDHSIQKALKVLRNKIRGIDPQ--------------------------DGLVLSVAGQTETLIQEATSEDNLSKMYIGWLPF 2367
BLAST of Serine-protein kinase ATM vs. Ensembl Yeast
Match: TOR1 (PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex that controls growth in response to nutrients by regulating translation, transcription, ribosome biogenesis, nutrient transport and autophagy; involved in meiosis; TOR1 has a paralog, TOR2, that arose from the whole genome duplication [Source:SGD;Acc:S000003827]) HSP 1 Score: 154.836 bits (390), Expect = 1.222e-37 Identity = 121/405 (29.88%), Postives = 196/405 (48.40%), Query Frame = 3
Query: 7176 IVGFDDVYSLQGGINLPKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKVIPMTQTSGIIEWCEDTVPLGDWLANDKTGAH---QRYRPQDSTPLQCRK--RLQISAE-ENIK--KRIETFKDIL--TKIQPVLGYFHFEKFPESQRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAFDLGKLMPT-QERVPFRLTRDLVHGLGPFGVEGRFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLHSW--KLNPQHARVLHTKREADNDCXXXXXXXXXXIEGFDN--KSRPGSSQNQMAERVILEMSRKFAGAVDSSY--LNCEGHVNYLIQTASNVENLARMFHGW 8339
I F+ ++S+ P+ + SDG + ++K ++D+RQDS++ Q+F +VN+LL N + R + I+ Y IP++ SG++ W VP D H + +R PL LQ++ + EN+ ++IE F L TK Q + K S+ W + R +Y SLA+ S+ G+ILGLGDRH N++LD T ++IHIDFG F+ L E+VPFRLTR L + + G+EG F+ TC +V+ +LR K+ ++ ++E DPL W L PQ + + + T+E N + ++N A V+ ++ K G + L+ V+ LIQ A+++E L + + GW
Sbjct: 2090 IAKFEPLFSVISSKQRPRKFSIKGSDGKDYKYVLKGHEDIRQDSLVMQLFGLVNTLLKNDSEC----------------FKRHLDIQQYPAIPLSPKSGLLGW----VPNSDTF-------HVLIREHRDAKKIPLNIEHWVMLQMAPDYENLTLLQKIEVFTYALDNTKGQDLYKILWL-KSRSSETWLERRTTYTRSLAVMSMTGYILGLGDRHPSNLMLDRITGKVIHIDFGDCFEAAILREKYPEKVPFRLTRMLTYAMEVSGIEGSFRITCENVMRVLRDNKESLMAILEAFALDPLIHWGFDLPPQKLTEQTGIPLPLINPSELLRKGAITVEEAANMEAEQQNETKNARAMLVLRRITDKLTGNDIKRFNELDVPEQVDKLIQQATSIERLCQHYIGW 2466
BLAST of Serine-protein kinase ATM vs. Ensembl Yeast
Match: PIK1 (Phosphatidylinositol 4-kinase; catalyzes first step in the biosynthesis of phosphatidylinositol-4,5-biphosphate; may control cytokinesis through the actin cytoskeleton; may control nonselective autophagy and mitophagy through trafficking of Atg9p [Source:SGD;Acc:S000005211]) HSP 1 Score: 61.6178 bits (148), Expect = 2.000e-9 Identity = 38/123 (30.89%), Postives = 63/123 (51.22%), Query Frame = 3
Query: 7695 PESQRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAFDLGKLMPTQERVPFRLTRDLVHGLGPFGVEG----RFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLH 8051
P ++ +A+ ++A+SLA S++ ++L + DRH NI++D N + HIDFG E PF+LT + + LG GVEG +F LR D I+++ E++ D +
Sbjct: 888 PNGFKYRRAQDNFASSLAAYSVICYLLQVKDRHNGNIMID-NEGHVSHIDFGFMLSNSPGSVGFEAAPFKLTYEYIELLG--GVEGEAFKKFVELTKSSFKALRKYADQIVSMCEIMQKDNMQ 1007
BLAST of Serine-protein kinase ATM vs. Ensembl Nematostella
Match: EDO36404 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SIS1]) HSP 1 Score: 456.833 bits (1174), Expect = 2.381e-131 Identity = 278/791 (35.15%), Postives = 433/791 (54.74%), Query Frame = 3
Query: 6105 DSQKHILTC-----QQIKRNHDLFFKLYFKAVSKICAWNQEYPVHSVSHIRTKILEP-AMGVFGKSLKQESDM---------LSTMSTFSYQQYTHINQYMRSSEYENRVKILTESKRDVSYLVDLRGKCPLR----KILEKQSEVDWDELNNLSQDRERFLLSAAISCSECLQNEDGNDFKIFHLMSMWLSNESNEKLNNIISDVIGKIETHKFLVLMPQLCARLN--SENNKSFEINLEKLIKRIILDHPFHSIYNLLAIRNANRDXXXXXXXXXXXXXXANDKMNS----------RISVAYTMVEQLVKESQSDIIRDADILTTAYIHWANVDMSAFKQ-----DIHKKLKFPLNCSLLRIAKQVKLPVPTLSIPIDRSLKYSLDRLPLIVGFDDVYSLQGGINLPKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKVIPMTQTSGIIEWCEDTVPLGDWL---ANDKTGAHQRYRPQDSTPLQCRKRLQISAEENIKKRIETFKDILTKIQPVLGYFHFEKFPESQRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAFDLGKLMPTQERVPFRLTRDLVHGLGPFGVEGRFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLHSWKLNPQHARVLHTKREADNDCXXXXXXXXXXIEGF---DNKSRPGSSQNQMAERVILEMSRKFAGAVDSSYLNCEGHVNYLIQTASNVENLARMFHGWQAYL 8351
++ H+L C Q + + +LY +A+ +W E + + I + LE + G + + ESD+ +++ ++ QY +I YM+SS++EN+ +I ++K + + L + + P R + L +SE+D +EL + + FL A + ++ LQ D D ++F L S+W N +++I+ D I +I++ KFL LM QL ARL S + +F+ L +LI+R +DHP H++ L+A+ NA+RD E + S R+ A ++E + + +++ L AYI A ++ K DI L +L +A VPT I +D +Y + + + F +SL GG+NLPKI+ C SDG+KRRQLVK DDLRQD+VM+QVF +VN LL N R + +RTYKVIP++Q SG++EWCE T+PLG++L TGAHQRY P+D +P+ CR+++ I I+ +PV +F EKF + WF+ R +Y S A +SIVG+I+GLGDRHVQNIL+D N+AEL+HID G+AF+ GK++PT E VPFRLTRDLV G+G GVEG F+ C + ++R+ ++ ++T++EVLL+DPL+SW L+P+ L + DND + S+T+ + +N S N+MAERV+ + +K G D++ L+ G VN+LI+ A +V+NL R+F GWQ ++
Sbjct: 965 ETAMHLLKCLTKQLQAVCMYDEEEIRLYPQALGLYGSWMAETRSENPNKIIEEYLEKHGRRISGLAYRGESDVHIVVPNIDAYLSLARYADTQYQNIVDYMKSSDFENKQEIARDAKSEYNRLSKVVAR-PERDKYIRTLMVESEIDEEELRLMEDSKMNFLQKALENYAKTLQAGDKYDLRVFRLCSLWFDNCKTSFVDDIMKDSISRIQSRKFLPLMYQLAARLGMRSSQDDAFQATLGQLIERTCVDHPHHTLLILIALVNADRDREYTAPSRRNGRDSRASRNASKETKGFIDEARLEAASALIES-ISHQRGQLVQMTKSLCLAYIELAYWEVGHLKGKTGPFDIKDTLAIKKMNNLRHVA------VPTSDIKVDPLCRY--EEIVYVDRFMPTFSLAGGVNLPKIIACVGSDGVKRRQLVKGRDDLRQDAVMEQVFGMVNQLLANNTETR----------------KRKLRVRTYKVIPLSQRSGMLEWCEGTMPLGEYLIGSPGHNTGAHQRYNPRDWSPMDCRRKMASVVRNYI------LIGIMDHFKPVFRHFFLEKFVDPAEWFERRLAYTRSCATSSIVGYIVGLGDRHVQNILVDCNSAELVHIDLGVAFEQGKVLPTPETVPFRLTRDLVDGMGVTGVEGVFRRCCEKTMAVMRTSQEALVTILEVLLYDPLYSWTLSPEKKMALQATK-PDNDVSEISSTAVDLVGDLPNGENTENGASVGNKMAERVLSRLKQKLNGIEDNTQLSVTGQVNHLIRQAMDVKNLCRLFPGWQPWV 1722
BLAST of Serine-protein kinase ATM vs. Ensembl Nematostella
Match: EDO44977 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RU99]) HSP 1 Score: 162.155 bits (409), Expect = 1.899e-39 Identity = 114/402 (28.36%), Postives = 196/402 (48.76%), Query Frame = 3
Query: 7224 PKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKVIPMTQTSGIIEWCEDTVPLGDWLANDKTGAHQRYRPQDSTPLQCRKRLQISAEEN-----IKKRIETFKDILTKIQPV-LGYFHFEKFPESQRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAFDLGKLMPT-QERVPFRLTRDLVHGLGPFGVEGRFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLHSWKLNPQHA-RVLHTKREADNDCXXXXXXXXXXIEGFD-NKSRPGSSQ-------------------NQMAERVILEMSRKFAGA--VDSSYLNCEGHVNYLIQTASNVENLARMFHGW 8339
P+ + S+G L+K ++DLRQD + Q+F +VN+LL + + R +SI+ Y VIP++ SG+I W VP D L + YR + L R+ ++ + + +++E F+ L L + K P S+ WF R +Y SLA+ S+VG++LGLGDRH N++LD T ++HIDFG F++ E++PFRLTR L + + G++G ++ TC V+ +R KD ++ ++E ++DPL +W+L A ++ +K +D + + + +EG D N+ +P + + N+ A +I + K G + + L+ V+ LI+ A+ ENL + + GW
Sbjct: 2098 PRKLCLAGSNGSDFMFLLKGHEDLRQDERVMQLFGLVNTLLASDPETS----------------KRHLSIQRYAVIPLSTNSGLIGW----VPHCDTLH----ALIRDYREKKKILLNIEHRIMLTMAPDYDHLTLMQKVEVFEHALANTNGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYVLGLGDRHPSNLMLDRLTGRILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGIDGNYRLTCESVMRTMREHKDSVMAVLEAFVYDPLLNWRLMDNAAPKIKRSKGRSDT----MTEAAEEMLEGVDVNRDKPSAKKPAEPLHSIEEETGHKPEFLNKKALDIITRVRDKLTGRDFANRNTLDVPTQVDLLIKQATAHENLCQCYIGW 2471
BLAST of Serine-protein kinase ATM vs. Ensembl Nematostella
Match: EDO29217 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T497]) HSP 1 Score: 145.206 bits (365), Expect = 6.301e-39 Identity = 80/235 (34.04%), Postives = 124/235 (52.77%), Query Frame = 3
Query: 7662 PVLGYFHFEKFPESQRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAFDLGKLMPTQERVPFRLTRDLVHGLGPFGVEGRFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLHSWKLNPQHARVLHTKREADNDCXXXXXXXXXXIEGFDNKSR-PGSSQNQMAERVILEMSRKFAGAVDSSY----LNCEGHVNYLIQTASNVENLARMFHGWQAYL 8351
PV G + + F W+++R +Y + A+ S+VG+ILGLGDRH +NIL D E +H+D F+ G+ ERVPFRLT +LV +G G EG ++ +C L L+RSQ D +LT++ +HDPL W L P+ G +KS+ G N+ A +++ + ++ G + L+ EG V+ LI A++++NLA+M+ GW YL
Sbjct: 4 PVFGEWFLKAFQNPTSWYESRLAYCRTTAVMSMVGYILGLGDRHGENILFDSTNGECVHVDLNCLFNKGETFDCPERVPFRLTHNLVDAMGLLGYEGVYRRSCEVTLRLMRSQCDSLLTVLGTFIHDPLMEW-LRPRGT------------------------PGDPSKSKDTGEVTNEEAVKILKSIEQRLKGYYSKNKIMIPLSIEGQVHKLITEATDIQNLAQMYIGWAPYL 213
BLAST of Serine-protein kinase ATM vs. Ensembl Nematostella
Match: EDO48437 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RJW4]) HSP 1 Score: 132.494 bits (332), Expect = 2.035e-30 Identity = 89/307 (28.99%), Postives = 152/307 (49.51%), Query Frame = 3
Query: 7224 PKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKVIPMTQTSGIIEWCEDTVPL-------------GDWLANDKTGAHQR----YRPQD-----STPLQCRKRLQISAEENIKKR--IETFKDILTKI-----QPVLGYFHFEKFPESQRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAFDLGKLMPTQERVPFRLTRDLVHGLGPFGVEGRFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLHSW 8057
PK + SDG + L K +DL D + Q S+ N++ +A+S + + A R Y V P+ SG+I+W + VP+ + L G++Q +P + TP K + + +E+ +K I + +L ++ +L + + W+ K+YA S A+ S++G+I+GLGDRH+ N+L+D T E++HID+ + F+ G+ + E+VPFR+T +L LG GVEG F+ +C VL +L+ ++ +LTL+E ++DPL W
Sbjct: 433 PKKLVFVGSDGQRHTYLFKGLEDLHLDERIMQFLSICNNMF-------TRADSHRCPLFCA---------RHYSVTPLGPRSGLIQWVDGAVPVFALYKRWQQREAATNALLKSAQGSNQPPPPPMKPSELFYSKMTPALKEKGI-VDPKESGRKEWPIAVMRQVLEELIAETPSDLLSRELWCSSTGALEWWHMTKTYARSTAVMSMIGYIIGLGDRHLDNMLIDFTTGEVVHIDYNVCFEKGRGLRVPEKVPFRMTPNLEMALGVTGVEGMFRLSCEQVLKILKQGRETLLTLLEAFVYDPLVDW 722
BLAST of Serine-protein kinase ATM vs. Ensembl Nematostella
Match: EDO34280 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SPT8]) HSP 1 Score: 131.339 bits (329), Expect = 4.082e-30 Identity = 108/417 (25.90%), Postives = 182/417 (43.65%), Query Frame = 3
Query: 7176 IVGFDDVYSLQGGINLPKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKVIPMTQTSGIIEWCEDTVPLGDWL-----ANDKTGAHQRYRPQDSTPLQCRKRLQI--SAEENIKKRIETFKDILTKIQPVLGYFHFEKFPES-QRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAF-DLGKLMPTQERVPFRLTRDLVHGLGPFGVEGRFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLHSWKL------NPQHARVLHTKREADNDCXXXXXXXXXXIEG----------FDNKSRPGSSQNQMAERVILEMSRKFAGAVDSSYLNCEGHVNYLIQTASNVENLARMFHGWQAYL 8351
I GFD+ + I PK V + D LVK +D+R D ++Q+F ++N ++ + + R + +RTY+VIPMTQ G+IEW ++T PL + L ++K R + ++ L R I S E N FK ++ L F++ S + + R +A + A I ++LG+GDRH+ N L+D+ T LI IDFG +F + +P E VPFRLTR + L P G + T V+ LR +++L ++V + +P W++ QH + + T+ + ++G + R S + + + + + L E V+ LI A++V L R + GW+A++
Sbjct: 1460 IAGFDEKVLVLASIRKPKRVTIRGDDERDHMFLVKGGEDIRLDQRIEQLFCMMNEVMSEDPACS----------------QRNLRLRTYQVIPMTQRVGLIEWLKNTKPLKELLHIAATESEKQAMVVRRKTKNMLDLTLRILFDIIISREANRTDTESEFKKKQAQVPWDLLRRAFQQLAASPEAYLTLRTHFARTHACICICQYVLGIGDRHLSNFLVDMRTGGLIGIDFGHSFGSATQFLPVPELVPFRLTRQFTNLLLPLKESGLVRNTMIHVMRALRGNHELLLNTMDVFVKEPSLDWQMFARKQAEDQHMEIGMYYEDLTWYPREKVLTAQRKLKGANPAFVTRQELELGHRRRSWFRNLQSACLGDRRHNVRAQKEENELTSEAQVDCLIDQATDVNILGRAWEGWEAWV 1860
BLAST of Serine-protein kinase ATM vs. Ensembl Medaka
Match: atr (ATR serine/threonine kinase [Source:NCBI gene;Acc:101157099]) HSP 1 Score: 181.03 bits (458), Expect = 8.628e-45 Identity = 147/595 (24.71%), Postives = 260/595 (43.70%), Query Frame = 3
Query: 6639 KLNNIISDVIGKIETHKFLVLMPQLCARLNSENNKSFEINLEKLIKRIILDHPFHSIYNLLAIRNANRDXXXXXXXXXXXXXXANDKMNSRISVAYTMVEQLVKESQSDIIRDADILTTAYIHWAN---------VDMSAFKQDIHKKLKFPLNCSLLRIAKQVKLPVPTLSIPIDRSLKYSLDRLPLIVGFDDVYSLQ--GGINLPKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKVIPMTQTSGIIEWCEDTVPLGDWLANDKTGAHQRYRPQDSTPLQCRKRLQISAEENIKKRIETFKDIL-TKIQPVLGYFHFEKFPESQRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAFDLGKLMPTQERVPFRLTRDLVHGLGPFGVEGRFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLHSWKLNPQHARVLHTKREADNDCXXXXXXXXXXIEGFDNKSRPGSSQNQ------MAERVILEMSRKFAGAVDSS------YLNCEGHVNYLIQTASNVENLARMFHGWQAYL 8351
K+N+I+S+ + ++FL QL +R+ +++ F L ++ ++ L +P +++ + A+ ++ + N + IS+ K S I DA+ LT + N + +S + + + ++ P +L + V +P ++P D P + D + ++ + PK + + SDG + K DDLR+D + + ++N L A R + IRTY VIP+ + GIIEW +T L L + Y+ + + ++L + ++++ K++L + PV + FP+ +R +Y S A+ S+VG++LGLGDRH +NIL D T E +H+DF F+ G+ E VPFRLT+++VH +GP G EG F+ C L L+R Q++ ++ L + LHDPL W +K G S+ Q +A+ + ++ ++ G + S L+ EGHV+YLIQ A++ + L +M+ GW YL
Sbjct: 1651 KINSIVSEHCANLAPYQFLTAFSQLISRVCHSSDEVFA-ALMNIVAKVFLAYPQQAMWLMAAVSKSS---------YHMRMNRCNQILKKAISL---------KPSLDKFIGDANRLTDKLLELCNKPVDGNSTTLSISVHFKQLKRLVEEPTFSQILIPLQSVLIP----TLPSTGGTNAKHDAFPGHWAYLDGFEVEILASLQKPKKISLRGSDGRSYTMMCKPKDDLRKDCRLMEFNCLINKCLRKH----------------AESRRRELHIRTYAVIPLNEECGIIEWVNNTAGLRHILT-------KLYKERVYLSGKELRKLILPKTAPFEEKLRIHKEVLCARHPPVFHEWFLRTFPDPT---SSRSAYCRSTAVMSMVGYVLGLGDRHGENILFDSFTGECVHVDFNCLFNKGETFDVPEVVPFRLTQNMVHAMGPMGTEGLFRQACEVTLRLMRDQREPLMVL-KTFLHDPLVEW-----------------------------------SKQTKGLSKTQVHETGEIAKTHVCDIEQRLLGVIKSRNKVLGLPLSIEGHVHYLIQEATDEKLLCQMYLGWGPYL 2160
BLAST of Serine-protein kinase ATM vs. Ensembl Medaka
Match: mtor (mechanistic target of rapamycin kinase [Source:ZFIN;Acc:ZDB-GENE-030131-2974]) HSP 1 Score: 155.221 bits (391), Expect = 8.050e-38 Identity = 121/412 (29.37%), Postives = 201/412 (48.79%), Query Frame = 3
Query: 7224 PKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKVIPMTQTSGIIEWCEDTVPLGDWLANDKTGAHQRYRPQDSTPLQCRKRLQISAEENIKKRIETFKDILTKIQPVLGYFH--------------FEKFPESQRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAFDLGKLMPT-QERVPFRLTRDLVHGLGPFGVEGRFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLHSWKLNPQHARVLHTKREADNDCXXXXXXXXXXIEGFD----NKSRPGSSQ------------------NQMAERVILEMSRKFAGAVDSSY---LNCEGHVNYLIQTASNVENLARMFHGW 8339
P+ + S+G + L+K ++DLRQD + Q+F +VN+LL N + K +SI+ Y VIP++ SG+I W VP D L + YR +K++ ++ E I R+ D LT ++ V + H + K P S+ WF R +Y SLA+ S+VG+ILGLGDRH N++LD + +++HIDFG F++ E++PFRLTR L + + G++G ++ TC V+ +LR +D ++ ++E ++DPL +W+L + + TKR + T+ S + +EG D + G++ N+ A ++I + K G D S+ L+ V LI+ A++ ENL + + GW
Sbjct: 357 PRKLTIMGSNGHEFMFLLKGHEDLRQDERVMQLFGLVNTLLANDPASLRKN----------------LSIQRYAVIPLSTNSGLIGW----VPHCDTLH----ALIRDYRE--------KKKILLNIEHRIMLRMAPDYDHLTLMEKVEVFEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRITCHTVMEVLREHRDSVMAVLEAFVYDPLLNWRLMDSNTK--GTKRSRTRTDSYTAGQSVEALEGIDLGETTHKKAGTTVPESIHSFIGDGLVQPEALNKKAIQIINRVRDKLTGR-DFSHDETLDVPTQVELLIKQATSHENLCQCYIGW 733
BLAST of Serine-protein kinase ATM vs. Ensembl Medaka
Match: prkdc (protein kinase, DNA-activated, catalytic subunit [Source:NCBI gene;Acc:101171206]) HSP 1 Score: 122.865 bits (307), Expect = 4.448e-27 Identity = 86/302 (28.48%), Postives = 141/302 (46.69%), Query Frame = 3
Query: 7176 IVGFDDVYSLQGGINLPKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKVIPMTQTSGIIEWCEDTVPLGDWLANDKTGAHQRYRPQDSTPLQCRKRLQISAEENIK-KRIETFKDILTKIQPVLG-----YFHFEKFPESQRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAF-DLGKLMPTQERVPFRLTRDLVHGLGPFGVEGRFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLHSWK 8060
I GFD+ + + PK + + D LVK +DLRQD ++Q+FS++N +L N + R + + TY+VIP+T T G+IEW E+T L D++ T EEN + KR + + L +Q V + PE+ + R + +S A+ + +ILG+GDRH+ N +++V T +I IDFG AF + +P E +PFRLT+ V+ + P G ++ L R++ D++L ++V + +P WK
Sbjct: 3589 ITGFDERVMVMSSMRHPKRLIIRGDDERDHPFLVKGGEDLRQDQRIEQLFSIMNIVLSNDTACV----------------QRGLQLHTYQVIPLT-TVGLIEWMENTCTLKDFVYKTMT-----------------------EEENKRAKRADAVNNFLKVLQHVPADLLRSFLRMCNSPEA--FLSLRSHFISSHALLCVSHWILGIGDRHLSNFMVNVETGGMIGIDFGHAFGSATQFLPVPELMPFRLTQQFVNLMQPLKESGLIQSIMVHSLRAYRAEPDLLLNTMDVFIKEPCLDWK 3848
BLAST of Serine-protein kinase ATM vs. Ensembl Medaka
Match: pik3c2g (phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma [Source:NCBI gene;Acc:105354205]) HSP 1 Score: 61.6178 bits (148), Expect = 1.294e-8 Identity = 65/261 (24.90%), Postives = 111/261 (42.53%), Query Frame = 3
Query: 7272 LVKSNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKVIPMTQTSGIIEWCEDTVPLGDWLANDKTGAHQRYRPQDSTPLQCRKRLQISAEENIKKRIETFKDILTKIQPVLGYFHFEKFPESQRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAFDLGKLMP--TQERVPFRLTRDLVHGLGPFG-VEGRFKT---TCCDVLNLLRSQKDIILTLIEVLL 8036
+ K+ DDL QD ++ Q+ V++S+ +G + +MI TY+ I + + G++E + V L G RY DS +E + +L K Q GY +A ++ +S A + FILG+ DRH NI+L +T + HIDFG ++ ++R PF T ++ H + G RF+ CC N++R + +IL+++E++L
Sbjct: 848 ICKTGDDLNQDMLVLQIVRVMDSVWLQEG-----------------LDLQMI---TYRCISIGKAQGLVEVVPEAVTLAKIHQQWGVGGALRY---DS--------------------LEKWFHMLNKTQD--GYD------------EAVMNFIHSCAGWCVATFILGICDRHNDNIMLK-STGHMFHIDFGKIMGNAQMFAGFKRDRTPFVFTSEMQHFITGGGKTPQRFQNFVELCCRAYNIIRGRSALILSMLELML 1050
BLAST of Serine-protein kinase ATM vs. Ensembl Medaka
Match: pik3c3 (phosphatidylinositol 3-kinase catalytic subunit type 3 [Source:NCBI gene;Acc:101175027]) HSP 1 Score: 60.077 bits (144), Expect = 3.603e-8 Identity = 67/297 (22.56%), Postives = 120/297 (40.40%), Query Frame = 3
Query: 7191 DVYSLQGGINLPKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKVIPMTQTSGIIEWCEDTVPLGDWLANDKT--GAHQRYRPQDSTPLQCRKRLQISAEENIKKRIETFKDILTKIQPVLGYFHFEKFPESQRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAFDLGKLMPTQERVPFRLTRDLVHGLGPFGVE--GRFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLHSWKLNP 8069
D +L +P + ++ DG + K DDLRQD ++ Q+ S+++ LL + N + + YKV+ + G +++ + +VP+ + LA + +++ P + P IS+E +Y S A ++ +ILG+GDRH+ N+LL T +L HIDFG + LG+ P +L++++V G+G E F+ C LR ++IL L +++ + L P
Sbjct: 595 DTATLFKSALMPAKLIFKTEDGAMYPVIFKHGDDLRQDQLILQIISLMDKLLRKE--------------------NLDLKLTPYKVLATSSKHGFMQFVQ-SVPVAEVLATEGNIQSFFRKHAPSEKGPYG------ISSE-------------------------------------VMDTYVKSCAGYCVITYILGVGDRHLDNLLL-TKTGKLFHIDFG--YILGRDP-KPLPPPMKLSKEMVEGMGGMQSEQYQEFRKQCYTAFLHLRRYSNLILNLFSLMVDANIPDIALEP 823
BLAST of Serine-protein kinase ATM vs. Planmine SMEST
Match: SMESG000023629.1 (SMESG000023629.1) HSP 1 Score: 3980.64 bits (10322), Expect = 0.000e+0 Identity = 2053/2059 (99.71%), Postives = 2057/2059 (99.90%), Query Frame = 3
Query: 1275 MRMLEVGLNNSNFVVRCQSQIAQIVSAINVCLNITNLSASVYSHLLKIVPKLMDKNLSSDNFCCLFESVFRCLLSESQALESLVTDTVSVLISIVKTGLLTTLPEGFWSKLMSLLPNESLFSFVSHVILHFNTNQPYRVLISVEISVQLLNWLLSFVCLPTTSFSDLSLLITVLVNRKSQKADCYTKQQCFPNQHRFPSVSYENAIKSCLLKQCPDFYPRTPITEVLQLSINSLDQSGMNILLKTFEIVSLTDSTDWLIVIFRFFRCLDQIDNPTKFRENIPVLRKAILHLKSIATLNQDLSPFLVEGLHSIDWKHLSALGTKIPELSQHISIMTAAVKACLVTSVFSHFNLTNLQQFRNQSHCYLSIFPDNLNGFIERFFTSFKLYNTNHIDLLRVFIESIASFKIRIKPEIISNLLMIIKESFKMFKRNYRVYGNLIEICLNIISILSDSFEMDNQKDFINCFHDLSGTINKIYMSYFPECHSIGRXXXXXXXXXFGYYWNNNSRIDPAGLLQARLSGICEAVFSNFSNGKSFSARLSASVFMEEVFRIAHPVVDLLEFFMKNFPENPLLITELWNSAGTDDELLYSDQNRARISSFLLMWTYSLSSEYSRRDISKFGSSVLPFITGRIPDISCQKPKSLSDFLSILYSKRFTSTMDITDFITAIMFPFIDNWIDLLADSQQPIELPGRVTISQIVQNNLKEFLWIISSCSDNDNRRSMISSYFPSVFDESQTVIDNLPNLVARIVISLDNSSSRCAAAALDYLLSILSIYEIRKLLNENILETIWEILSHLWEISRSFERFDRISIVLFSEYLNLPMSLSEWLLSKSGRLIDLVMFIVGKYSTDDIQDSYPSIWCLIIDIILSSCDNWHHNTNINPINDQFIGFLIIRHIRLLEISSKNHDNNDLQLLTLLIRLVSFSHRNIEAPNLDVNIFWYQKAFYFIAECSEKYINHKXXXXXXXXXXXXXPVTKYGGNLDGFIYRISGFNSFPSIILLRPEIDGISSIRNILISFDKFGLIILEKKTKSFVLLSEFLYGLLQTERIDPSIGDLLQKLQDILHLFLVSKMEIFPSLKSPETSDAIISCLMYLKLLLPQYHISPNQQLAIVGKFDQDPVISDQIDLLYHLSIICLQDFGNRSWXXXXXXXXXXQSINTSKNRFLTDILSLFHLDXXXXXXXXXYEKNLDFPAILKFLENSIPFCSHTQWRCELTKMLAVRSSKPVYNRCHPELVSSVGSISFYCLPRIFATVEFSTEETRILSQVINRILHEQHYCESRKIVLVDCVVKKLEYIIIEEGNCRNNWEDIDFFKAAEVAYCGKMYTATLMLLDKLWLKESNAEMNAGIVNLYYKTFKSLASQEDLTADRFLIXXXXXXXXXXXXXXXXXXLLWLIKNGKFKVLHRLLKAEKNSDIFSFKPEAKIDILWKLTRWGDEEKLEINNLSQENVCSLAMYDFLYSRSEHVSEFYRNHVVDSCKISWDQEACFRPLIERATLFGNETSLPTILESLIRIANKSNIDQLDSSIVWALIRSNRFARNLEIVNQQLLGISDLAKRCKRHEYIDFIRDMLNLHEVDNSILKCSGESSLFRTIDIFSQKTETEETKKSFLQLEQFIYDSQKHILTCQQIKRNHDLFFKLYFKAVSKICAWNQEYPVHSVSHIRTKILEPAMGVFGKSLKQESDMLSTMSTFSYQQYTHINQYMRSSEYENRVKILTESKRDVSYLVDLRGKCPLRKILEKQSEVDWDELNNLSQDRERFLLSAAISCSECLQNEDGNDFKIFHLMSMWLSNESNEKLNNIISDVIGKIETHKFLVLMPQLCARLNSENNKSFEINLEKLIKRIILDHPFHSIYNLLAIRNANRDXXXXXXXXXXXXXXANDKMNSRISVAYTMVEQLVKESQSDIIRDADILTTAYIHWANVDMSAFKQDIHKKLKFPLNCSLLRIAKQVKLPVPTLSIPIDRSLKYSLDRLPLIVGFDDVYSLQGGINLPKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKVI 7451
MRMLEVGLNNSNFVVRCQSQIAQIVSAINVCLNITNLSASVYSHLLKIVPKLMDKNLSSDNFCCLFESVFRCLLSESQALESLVTDTVSVLISIVKTGLLTTLPEGFWSKLMSLLPNESLFSFVSHVILHFNTNQPYRVLISVEISVQLLNWLLSFVCLPTTSFSDLSLLITVLVNRKSQKADCYTKQQCFPNQHRFPSVSYENAIKSCLLKQCPDFYPRTPITEVLQLSINSLDQSGMNILLKTFEIVSLTDSTDWLIVIFRFFRCLDQIDNPTKFRENIPVLRKAILHLKSIATLNQDLSPFLVEGLHSIDWKHLSALGTKIPELSQHISIMTAAVKACLVTSVFSHFNLTNLQQFRNQSHCYLSIFPDNLNGFIERFFTSFKLYNTNHIDLLRVFIESIASFKIRIKPEIISNLLMIIKESFKMFKRNYRVYGNLIEICLNIISILSDSFEMDNQKDFINCFHDLSGTINKIYMSYFPECHSIGRLLAKLLALLFGYYWNNNSRIDPAGLLQARLSGICEAVFSNFSNGKSFSARLSASVFMEEVFRIAHPVVDLLEFFMKNFPENPLLITELWNSAGTDDELLYSDQNRARISSFLLMWTYSLSSEYSRRDISKFGSSVLPFITGRIPDISCQKPKSLSDFLSILYSKRFTSTMDITDFITAIMFPFIDNWIDLLADSQQPIELPGRVTISQIVQNNLKEFLWIISSCSDNDNRRSMISSYFPSVFDESQTVIDNLPNLVARIVISLDNSSSRCAAAALDYLLSILSIYEIRKLLNENILETIWEILSHLWEISRS+ERFDRISIVLFSEYLNLPMSLSEWLLSKSGRLIDLVMFIVGKYSTDDIQDSYPSIWCLIIDIILSSCDNWHHNTNINPINDQFIGFLIIRHIRLLEISSKNHDNNDLQLLTLLIRL+SFSHRNIEAPNLDVNIFWYQKAFYFIAECSEKYINHKSIIDDIISELLSSPVTKYGGNLDGFIYRISGFNSFPSIILLRPEIDGISSIRNILISFDKFGLIILEKKTKSFVLLSEFLYGLLQTERIDPSIGDLLQKLQDILHLFLVSKMEIFPSLKSPETSDAIISCLMYLKLLLPQYHISPNQQLAIVGKFDQDPVISDQIDLLYHLSIICLQDFGNRSWCSYLSLCSLYQSINTSKNRFLTDILSLFHLDKNNKKINIIYEKNLDFPAILKFLENSIPFCSHTQWRCELTKMLAVRSSKPVYNRCHPELVSSVGSISFYCLPRIFATVEFSTEETRILSQVINRILHEQHYCESRKIVLVDCVVKKLEYIIIEEGNCRNNWEDIDFFKAAEVAYCGKMYTATLMLLDKLWLKESNAEMNAGIVNLYYKTFKSLASQEDLTADRFLIGSSSQYNDYGDGDGDSNDLLWLIKNGKFKVLHRLLKAEKNSDIFSFKPEAKIDILWKLTRWGDEEKLEINNLSQENVCSLAMYDFLYSRSEHVSEFYRNHVVDSCKISWDQE CFRPLIERATLFGNETSLPTILESLIRIANKSNIDQLDSSIVWALIRSNRFARNLEIVNQQLLGISDLAKRCKRHEYIDFIRDMLNLHE+DNSILKCSGESSLFRTIDIFSQKTETEETKKSFLQLEQFIYDSQKHILTCQQIKRNHDLFFKLYFKAVSKICAWNQEYPVHSVSHIRTKILEPAMGVFGKSLKQESDMLSTMSTFSYQQYTHINQYMRSSEYENRVKILTESKRDVSYLVDLRGKCPLRKILEKQSEVDWDELNNLSQDRERFLLSAAISCSECLQNEDGNDFKIFHLMSMWLSNESNEKLNNIISDVIGKIETHKFLVLMPQLCARLNSENNKSFEINLEKLIKRIILDHPFHSIYNLLAIRNANRDSELEKSKSLKSIKEANDKMNSRISVAYTMVEQLVKESQSDIIRDADILTTAYIHWANVDMSAFKQDIHKKLKFPLNCSLLRIAKQVKLPVPTLSIPIDRSLKYSLDRLPLIVGFDDVYSLQGGINLPKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYK +
Sbjct: 1 MRMLEVGLNNSNFVVRCQSQIAQIVSAINVCLNITNLSASVYSHLLKIVPKLMDKNLSSDNFCCLFESVFRCLLSESQALESLVTDTVSVLISIVKTGLLTTLPEGFWSKLMSLLPNESLFSFVSHVILHFNTNQPYRVLISVEISVQLLNWLLSFVCLPTTSFSDLSLLITVLVNRKSQKADCYTKQQCFPNQHRFPSVSYENAIKSCLLKQCPDFYPRTPITEVLQLSINSLDQSGMNILLKTFEIVSLTDSTDWLIVIFRFFRCLDQIDNPTKFRENIPVLRKAILHLKSIATLNQDLSPFLVEGLHSIDWKHLSALGTKIPELSQHISIMTAAVKACLVTSVFSHFNLTNLQQFRNQSHCYLSIFPDNLNGFIERFFTSFKLYNTNHIDLLRVFIESIASFKIRIKPEIISNLLMIIKESFKMFKRNYRVYGNLIEICLNIISILSDSFEMDNQKDFINCFHDLSGTINKIYMSYFPECHSIGRLLAKLLALLFGYYWNNNSRIDPAGLLQARLSGICEAVFSNFSNGKSFSARLSASVFMEEVFRIAHPVVDLLEFFMKNFPENPLLITELWNSAGTDDELLYSDQNRARISSFLLMWTYSLSSEYSRRDISKFGSSVLPFITGRIPDISCQKPKSLSDFLSILYSKRFTSTMDITDFITAIMFPFIDNWIDLLADSQQPIELPGRVTISQIVQNNLKEFLWIISSCSDNDNRRSMISSYFPSVFDESQTVIDNLPNLVARIVISLDNSSSRCAAAALDYLLSILSIYEIRKLLNENILETIWEILSHLWEISRSYERFDRISIVLFSEYLNLPMSLSEWLLSKSGRLIDLVMFIVGKYSTDDIQDSYPSIWCLIIDIILSSCDNWHHNTNINPINDQFIGFLIIRHIRLLEISSKNHDNNDLQLLTLLIRLISFSHRNIEAPNLDVNIFWYQKAFYFIAECSEKYINHKSIIDDIISELLSSPVTKYGGNLDGFIYRISGFNSFPSIILLRPEIDGISSIRNILISFDKFGLIILEKKTKSFVLLSEFLYGLLQTERIDPSIGDLLQKLQDILHLFLVSKMEIFPSLKSPETSDAIISCLMYLKLLLPQYHISPNQQLAIVGKFDQDPVISDQIDLLYHLSIICLQDFGNRSWCSYLSLCSLYQSINTSKNRFLTDILSLFHLDKNNKKINIIYEKNLDFPAILKFLENSIPFCSHTQWRCELTKMLAVRSSKPVYNRCHPELVSSVGSISFYCLPRIFATVEFSTEETRILSQVINRILHEQHYCESRKIVLVDCVVKKLEYIIIEEGNCRNNWEDIDFFKAAEVAYCGKMYTATLMLLDKLWLKESNAEMNAGIVNLYYKTFKSLASQEDLTADRFLIGSSSQYNDYGDGDGDSNDLLWLIKNGKFKVLHRLLKAEKNSDIFSFKPEAKIDILWKLTRWGDEEKLEINNLSQENVCSLAMYDFLYSRSEHVSEFYRNHVVDSCKISWDQEVCFRPLIERATLFGNETSLPTILESLIRIANKSNIDQLDSSIVWALIRSNRFARNLEIVNQQLLGISDLAKRCKRHEYIDFIRDMLNLHEIDNSILKCSGESSLFRTIDIFSQKTETEETKKSFLQLEQFIYDSQKHILTCQQIKRNHDLFFKLYFKAVSKICAWNQEYPVHSVSHIRTKILEPAMGVFGKSLKQESDMLSTMSTFSYQQYTHINQYMRSSEYENRVKILTESKRDVSYLVDLRGKCPLRKILEKQSEVDWDELNNLSQDRERFLLSAAISCSECLQNEDGNDFKIFHLMSMWLSNESNEKLNNIISDVIGKIETHKFLVLMPQLCARLNSENNKSFEINLEKLIKRIILDHPFHSIYNLLAIRNANRDSELEKSKSLKSIKEANDKMNSRISVAYTMVEQLVKESQSDIIRDADILTTAYIHWANVDMSAFKQDIHKKLKFPLNCSLLRIAKQVKLPVPTLSIPIDRSLKYSLDRLPLIVGFDDVYSLQGGINLPKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKFL 2059
BLAST of Serine-protein kinase ATM vs. Planmine SMEST
Match: SMESG000023629.1 (SMESG000023629.1) HSP 1 Score: 3977.17 bits (10313), Expect = 0.000e+0 Identity = 2051/2057 (99.71%), Postives = 2055/2057 (99.90%), Query Frame = 3
Query: 1281 MLEVGLNNSNFVVRCQSQIAQIVSAINVCLNITNLSASVYSHLLKIVPKLMDKNLSSDNFCCLFESVFRCLLSESQALESLVTDTVSVLISIVKTGLLTTLPEGFWSKLMSLLPNESLFSFVSHVILHFNTNQPYRVLISVEISVQLLNWLLSFVCLPTTSFSDLSLLITVLVNRKSQKADCYTKQQCFPNQHRFPSVSYENAIKSCLLKQCPDFYPRTPITEVLQLSINSLDQSGMNILLKTFEIVSLTDSTDWLIVIFRFFRCLDQIDNPTKFRENIPVLRKAILHLKSIATLNQDLSPFLVEGLHSIDWKHLSALGTKIPELSQHISIMTAAVKACLVTSVFSHFNLTNLQQFRNQSHCYLSIFPDNLNGFIERFFTSFKLYNTNHIDLLRVFIESIASFKIRIKPEIISNLLMIIKESFKMFKRNYRVYGNLIEICLNIISILSDSFEMDNQKDFINCFHDLSGTINKIYMSYFPECHSIGRXXXXXXXXXFGYYWNNNSRIDPAGLLQARLSGICEAVFSNFSNGKSFSARLSASVFMEEVFRIAHPVVDLLEFFMKNFPENPLLITELWNSAGTDDELLYSDQNRARISSFLLMWTYSLSSEYSRRDISKFGSSVLPFITGRIPDISCQKPKSLSDFLSILYSKRFTSTMDITDFITAIMFPFIDNWIDLLADSQQPIELPGRVTISQIVQNNLKEFLWIISSCSDNDNRRSMISSYFPSVFDESQTVIDNLPNLVARIVISLDNSSSRCAAAALDYLLSILSIYEIRKLLNENILETIWEILSHLWEISRSFERFDRISIVLFSEYLNLPMSLSEWLLSKSGRLIDLVMFIVGKYSTDDIQDSYPSIWCLIIDIILSSCDNWHHNTNINPINDQFIGFLIIRHIRLLEISSKNHDNNDLQLLTLLIRLVSFSHRNIEAPNLDVNIFWYQKAFYFIAECSEKYINHKXXXXXXXXXXXXXPVTKYGGNLDGFIYRISGFNSFPSIILLRPEIDGISSIRNILISFDKFGLIILEKKTKSFVLLSEFLYGLLQTERIDPSIGDLLQKLQDILHLFLVSKMEIFPSLKSPETSDAIISCLMYLKLLLPQYHISPNQQLAIVGKFDQDPVISDQIDLLYHLSIICLQDFGNRSWXXXXXXXXXXQSINTSKNRFLTDILSLFHLDXXXXXXXXXYEKNLDFPAILKFLENSIPFCSHTQWRCELTKMLAVRSSKPVYNRCHPELVSSVGSISFYCLPRIFATVEFSTEETRILSQVINRILHEQHYCESRKIVLVDCVVKKLEYIIIEEGNCRNNWEDIDFFKAAEVAYCGKMYTATLMLLDKLWLKESNAEMNAGIVNLYYKTFKSLASQEDLTADRFLIXXXXXXXXXXXXXXXXXXLLWLIKNGKFKVLHRLLKAEKNSDIFSFKPEAKIDILWKLTRWGDEEKLEINNLSQENVCSLAMYDFLYSRSEHVSEFYRNHVVDSCKISWDQEACFRPLIERATLFGNETSLPTILESLIRIANKSNIDQLDSSIVWALIRSNRFARNLEIVNQQLLGISDLAKRCKRHEYIDFIRDMLNLHEVDNSILKCSGESSLFRTIDIFSQKTETEETKKSFLQLEQFIYDSQKHILTCQQIKRNHDLFFKLYFKAVSKICAWNQEYPVHSVSHIRTKILEPAMGVFGKSLKQESDMLSTMSTFSYQQYTHINQYMRSSEYENRVKILTESKRDVSYLVDLRGKCPLRKILEKQSEVDWDELNNLSQDRERFLLSAAISCSECLQNEDGNDFKIFHLMSMWLSNESNEKLNNIISDVIGKIETHKFLVLMPQLCARLNSENNKSFEINLEKLIKRIILDHPFHSIYNLLAIRNANRDXXXXXXXXXXXXXXANDKMNSRISVAYTMVEQLVKESQSDIIRDADILTTAYIHWANVDMSAFKQDIHKKLKFPLNCSLLRIAKQVKLPVPTLSIPIDRSLKYSLDRLPLIVGFDDVYSLQGGINLPKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKVI 7451
MLEVGLNNSNFVVRCQSQIAQIVSAINVCLNITNLSASVYSHLLKIVPKLMDKNLSSDNFCCLFESVFRCLLSESQALESLVTDTVSVLISIVKTGLLTTLPEGFWSKLMSLLPNESLFSFVSHVILHFNTNQPYRVLISVEISVQLLNWLLSFVCLPTTSFSDLSLLITVLVNRKSQKADCYTKQQCFPNQHRFPSVSYENAIKSCLLKQCPDFYPRTPITEVLQLSINSLDQSGMNILLKTFEIVSLTDSTDWLIVIFRFFRCLDQIDNPTKFRENIPVLRKAILHLKSIATLNQDLSPFLVEGLHSIDWKHLSALGTKIPELSQHISIMTAAVKACLVTSVFSHFNLTNLQQFRNQSHCYLSIFPDNLNGFIERFFTSFKLYNTNHIDLLRVFIESIASFKIRIKPEIISNLLMIIKESFKMFKRNYRVYGNLIEICLNIISILSDSFEMDNQKDFINCFHDLSGTINKIYMSYFPECHSIGRLLAKLLALLFGYYWNNNSRIDPAGLLQARLSGICEAVFSNFSNGKSFSARLSASVFMEEVFRIAHPVVDLLEFFMKNFPENPLLITELWNSAGTDDELLYSDQNRARISSFLLMWTYSLSSEYSRRDISKFGSSVLPFITGRIPDISCQKPKSLSDFLSILYSKRFTSTMDITDFITAIMFPFIDNWIDLLADSQQPIELPGRVTISQIVQNNLKEFLWIISSCSDNDNRRSMISSYFPSVFDESQTVIDNLPNLVARIVISLDNSSSRCAAAALDYLLSILSIYEIRKLLNENILETIWEILSHLWEISRS+ERFDRISIVLFSEYLNLPMSLSEWLLSKSGRLIDLVMFIVGKYSTDDIQDSYPSIWCLIIDIILSSCDNWHHNTNINPINDQFIGFLIIRHIRLLEISSKNHDNNDLQLLTLLIRL+SFSHRNIEAPNLDVNIFWYQKAFYFIAECSEKYINHKSIIDDIISELLSSPVTKYGGNLDGFIYRISGFNSFPSIILLRPEIDGISSIRNILISFDKFGLIILEKKTKSFVLLSEFLYGLLQTERIDPSIGDLLQKLQDILHLFLVSKMEIFPSLKSPETSDAIISCLMYLKLLLPQYHISPNQQLAIVGKFDQDPVISDQIDLLYHLSIICLQDFGNRSWCSYLSLCSLYQSINTSKNRFLTDILSLFHLDKNNKKINIIYEKNLDFPAILKFLENSIPFCSHTQWRCELTKMLAVRSSKPVYNRCHPELVSSVGSISFYCLPRIFATVEFSTEETRILSQVINRILHEQHYCESRKIVLVDCVVKKLEYIIIEEGNCRNNWEDIDFFKAAEVAYCGKMYTATLMLLDKLWLKESNAEMNAGIVNLYYKTFKSLASQEDLTADRFLIGSSSQYNDYGDGDGDSNDLLWLIKNGKFKVLHRLLKAEKNSDIFSFKPEAKIDILWKLTRWGDEEKLEINNLSQENVCSLAMYDFLYSRSEHVSEFYRNHVVDSCKISWDQE CFRPLIERATLFGNETSLPTILESLIRIANKSNIDQLDSSIVWALIRSNRFARNLEIVNQQLLGISDLAKRCKRHEYIDFIRDMLNLHE+DNSILKCSGESSLFRTIDIFSQKTETEETKKSFLQLEQFIYDSQKHILTCQQIKRNHDLFFKLYFKAVSKICAWNQEYPVHSVSHIRTKILEPAMGVFGKSLKQESDMLSTMSTFSYQQYTHINQYMRSSEYENRVKILTESKRDVSYLVDLRGKCPLRKILEKQSEVDWDELNNLSQDRERFLLSAAISCSECLQNEDGNDFKIFHLMSMWLSNESNEKLNNIISDVIGKIETHKFLVLMPQLCARLNSENNKSFEINLEKLIKRIILDHPFHSIYNLLAIRNANRDSELEKSKSLKSIKEANDKMNSRISVAYTMVEQLVKESQSDIIRDADILTTAYIHWANVDMSAFKQDIHKKLKFPLNCSLLRIAKQVKLPVPTLSIPIDRSLKYSLDRLPLIVGFDDVYSLQGGINLPKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYK +
Sbjct: 1 MLEVGLNNSNFVVRCQSQIAQIVSAINVCLNITNLSASVYSHLLKIVPKLMDKNLSSDNFCCLFESVFRCLLSESQALESLVTDTVSVLISIVKTGLLTTLPEGFWSKLMSLLPNESLFSFVSHVILHFNTNQPYRVLISVEISVQLLNWLLSFVCLPTTSFSDLSLLITVLVNRKSQKADCYTKQQCFPNQHRFPSVSYENAIKSCLLKQCPDFYPRTPITEVLQLSINSLDQSGMNILLKTFEIVSLTDSTDWLIVIFRFFRCLDQIDNPTKFRENIPVLRKAILHLKSIATLNQDLSPFLVEGLHSIDWKHLSALGTKIPELSQHISIMTAAVKACLVTSVFSHFNLTNLQQFRNQSHCYLSIFPDNLNGFIERFFTSFKLYNTNHIDLLRVFIESIASFKIRIKPEIISNLLMIIKESFKMFKRNYRVYGNLIEICLNIISILSDSFEMDNQKDFINCFHDLSGTINKIYMSYFPECHSIGRLLAKLLALLFGYYWNNNSRIDPAGLLQARLSGICEAVFSNFSNGKSFSARLSASVFMEEVFRIAHPVVDLLEFFMKNFPENPLLITELWNSAGTDDELLYSDQNRARISSFLLMWTYSLSSEYSRRDISKFGSSVLPFITGRIPDISCQKPKSLSDFLSILYSKRFTSTMDITDFITAIMFPFIDNWIDLLADSQQPIELPGRVTISQIVQNNLKEFLWIISSCSDNDNRRSMISSYFPSVFDESQTVIDNLPNLVARIVISLDNSSSRCAAAALDYLLSILSIYEIRKLLNENILETIWEILSHLWEISRSYERFDRISIVLFSEYLNLPMSLSEWLLSKSGRLIDLVMFIVGKYSTDDIQDSYPSIWCLIIDIILSSCDNWHHNTNINPINDQFIGFLIIRHIRLLEISSKNHDNNDLQLLTLLIRLISFSHRNIEAPNLDVNIFWYQKAFYFIAECSEKYINHKSIIDDIISELLSSPVTKYGGNLDGFIYRISGFNSFPSIILLRPEIDGISSIRNILISFDKFGLIILEKKTKSFVLLSEFLYGLLQTERIDPSIGDLLQKLQDILHLFLVSKMEIFPSLKSPETSDAIISCLMYLKLLLPQYHISPNQQLAIVGKFDQDPVISDQIDLLYHLSIICLQDFGNRSWCSYLSLCSLYQSINTSKNRFLTDILSLFHLDKNNKKINIIYEKNLDFPAILKFLENSIPFCSHTQWRCELTKMLAVRSSKPVYNRCHPELVSSVGSISFYCLPRIFATVEFSTEETRILSQVINRILHEQHYCESRKIVLVDCVVKKLEYIIIEEGNCRNNWEDIDFFKAAEVAYCGKMYTATLMLLDKLWLKESNAEMNAGIVNLYYKTFKSLASQEDLTADRFLIGSSSQYNDYGDGDGDSNDLLWLIKNGKFKVLHRLLKAEKNSDIFSFKPEAKIDILWKLTRWGDEEKLEINNLSQENVCSLAMYDFLYSRSEHVSEFYRNHVVDSCKISWDQEVCFRPLIERATLFGNETSLPTILESLIRIANKSNIDQLDSSIVWALIRSNRFARNLEIVNQQLLGISDLAKRCKRHEYIDFIRDMLNLHEIDNSILKCSGESSLFRTIDIFSQKTETEETKKSFLQLEQFIYDSQKHILTCQQIKRNHDLFFKLYFKAVSKICAWNQEYPVHSVSHIRTKILEPAMGVFGKSLKQESDMLSTMSTFSYQQYTHINQYMRSSEYENRVKILTESKRDVSYLVDLRGKCPLRKILEKQSEVDWDELNNLSQDRERFLLSAAISCSECLQNEDGNDFKIFHLMSMWLSNESNEKLNNIISDVIGKIETHKFLVLMPQLCARLNSENNKSFEINLEKLIKRIILDHPFHSIYNLLAIRNANRDSELEKSKSLKSIKEANDKMNSRISVAYTMVEQLVKESQSDIIRDADILTTAYIHWANVDMSAFKQDIHKKLKFPLNCSLLRIAKQVKLPVPTLSIPIDRSLKYSLDRLPLIVGFDDVYSLQGGINLPKIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKFL 2057
BLAST of Serine-protein kinase ATM vs. Planmine SMEST
Match: SMESG000023630.1 (SMESG000023630.1) HSP 1 Score: 525.783 bits (1353), Expect = 9.913e-171 Identity = 258/259 (99.61%), Postives = 258/259 (99.61%), Query Frame = 3
Query: 42 MESGRDVMTMFDITNIPKTKENIEKRLSLIKDSFLTFDSRGNVNDEYFNLKTHFDWYPFCQFLIKISMSFFELIVKKKSATTDLYKTPMNKKILDDIVYIYHFTLNNIDPENMNMDINGLLNNALNLTHQMVSTNLDMVQRFVNLIFTETIFDDKFAIVGEINIQFWEKAERFLCTLILNMRESDSQKSTLFLKSVFLIYKAMTPFKYPDLVLIIRTINHITSWNFCQNDKLALDIHGYISAIINQLILTVGTDAIKCL 818
MESGRDVMTMFDITNIPKTKENIEKRLSLIKDSFLTFDSRGNVNDEYFNLKTHFDWYPFCQFLIKISMSFFELIVKKKSATTDLYKTPMNKKILDDIVYIYHFTLNNIDPENMNMDINGLLNNALNLTHQMVSTNLDMVQRFVNLIFTETIFDDKFAIVGEINIQFWEKAERFLCTLILNMRESDSQKSTLFLKSVFLIYKAMTPFKYPDLVLIIRTINHITSWNFCQNDKLALDIHGYISAIINQLILTVGTDAIK L
Sbjct: 1 MESGRDVMTMFDITNIPKTKENIEKRLSLIKDSFLTFDSRGNVNDEYFNLKTHFDWYPFCQFLIKISMSFFELIVKKKSATTDLYKTPMNKKILDDIVYIYHFTLNNIDPENMNMDINGLLNNALNLTHQMVSTNLDMVQRFVNLIFTETIFDDKFAIVGEINIQFWEKAERFLCTLILNMRESDSQKSTLFLKSVFLIYKAMTPFKYPDLVLIIRTINHITSWNFCQNDKLALDIHGYISAIINQLILTVGTDAIKYL 259
BLAST of Serine-protein kinase ATM vs. Planmine SMEST
Match: SMESG000023628.1 (SMESG000023628.1) HSP 1 Score: 317.39 bits (812), Expect = 1.561e-99 Identity = 159/159 (100.00%), Postives = 159/159 (100.00%), Query Frame = 3
Query: 7875 MPTQERVPFRLTRDLVHGLGPFGVEGRFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLHSWKLNPQHARVLHTKREADNDCXXXXXXXXXXIEGFDNKSRPGSSQNQMAERVILEMSRKFAGAVDSSYLNCEGHVNYLIQTASNVENLARMFHGWQAYL 8351
MPTQERVPFRLTRDLVHGLGPFGVEGRFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLHSWKLNPQHARVLHTKREADNDCNNTSNTSSKTIEGFDNKSRPGSSQNQMAERVILEMSRKFAGAVDSSYLNCEGHVNYLIQTASNVENLARMFHGWQAYL
Sbjct: 1 MPTQERVPFRLTRDLVHGLGPFGVEGRFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLHSWKLNPQHARVLHTKREADNDCNNTSNTSSKTIEGFDNKSRPGSSQNQMAERVILEMSRKFAGAVDSSYLNCEGHVNYLIQTASNVENLARMFHGWQAYL 159
BLAST of Serine-protein kinase ATM vs. Planmine SMEST
Match: SMESG000018015.1 (SMESG000018015.1) HSP 1 Score: 174.866 bits (442), Expect = 3.503e-43 Identity = 115/376 (30.59%), Postives = 185/376 (49.20%), Query Frame = 3
Query: 7227 KIVWCQSSDGLKRRQLVKSNDDLRQDSVMQQVFSVVNSLLGNKGSITYKANSIKSSDWSAFIYNRMISIRTYKVIPMTQTSGIIEWCEDTVPLGDWLANDKTGAHQRYRPQDSTPLQCRKRLQISAEENIKKRIETFKDILTKIQPVLGYFHFEKFPESQRWFKARKSYANSLAINSIVGFILGLGDRHVQNILLDVNTAELIHIDFGIAFDLGKLMPTQERVPFRLTRDLVHGLGPFGV-EGRFKTTCCDVLNLLRSQKDIILTLIEVLLHDPLHSWKLNPQHARVLHTKREADNDCXXXXXXXXXXIEGFDNKSRPGSSQNQMAERVILEMSRKFAGAVDSSYLNCEGHVNYLIQTASNVENLARMFHGWQAYL 8351
K++W +DG K +VK DDLR+D + ++ + N L+ + R++ IRTY V P+ + SG+IEW +T + + QR P L R + + E KK ++ K++L V + +KFPE W+++ + Y S+A+ S+VG+ILGLGDRH++NIL D + +++HID+ F+ GK + E VPFRLTR++ GLGP G G F+++C LNLLR++ + I+ + + + +D L K +P KS S+ M E + EM + G V+ L+ EG VNYLI A + + L +M+ GW +++
Sbjct: 1062 KMIWI-GTDGKKYIMIVKPKDDLRRDCRIMELNGMFNRLMRRNSETRH----------------RLLYIRTYAVTPLGEKSGLIEWVNNTESFRQVVVDLHI---QRNNPIIWQKLHARYAQRGDSFE--KKLMKFTKEVLPLYPVVFNKWFLQKFPEPNAWYRSVQKYCRSVAVMSMVGYILGLGDRHIENILFDHTSGDVVHIDYNCLFNHGKTLEWPEVVPFRLTRNMQDGLGPCGENNGLFRSSCVATLNLLRNEIEPIMAVFKPMYYDTLTEVK-DPLI------------------------------KSNKQSNAVTMTENKLEEMENRLKGKVNQLPLSVEGEVNYLIAQAIDEKLLCQMYMGWGSFI 1384 The following BLAST results are available for this feature:
BLAST of Serine-protein kinase ATM vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Serine-protein kinase ATM vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Serine-protein kinase ATM vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Serine-protein kinase ATM vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Serine-protein kinase ATM vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Serine-protein kinase ATM vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Serine-protein kinase ATM vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Serine-protein kinase ATM vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Serine-protein kinase ATM vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Serine-protein kinase ATM vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Serine-protein kinase ATM vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of Serine-protein kinase ATM vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Serine-protein kinase ATM vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Serine-protein kinase ATM vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30019647 ID=SMED30019647|Name=Serine-protein kinase ATM|organism=Schmidtea mediterranea sexual|type=transcript|length=8400bpback to top protein sequence of SMED30019647-orf-1 >SMED30019647-orf-1 ID=SMED30019647-orf-1|Name=SMED30019647-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=2771bp MESGRDVMTMFDITNIPKTKENIEKRLSLIKDSFLTFDSRGNVNDEYFNLback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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