serrate RNA effector molecule
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30019623 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 10
Homology
BLAST of serrate RNA effector molecule vs. Ensembl Human
Match: SRRT (serrate, RNA effector molecule [Source:HGNC Symbol;Acc:HGNC:24101]) HSP 1 Score: 371.318 bits (952), Expect = 2.529e-118 Identity = 190/362 (52.49%), Postives = 256/362 (70.72%), Query Frame = 2
Query: 1091 EPRALHKTFSIFLRNLHPNVLRSEIEALVKPYSGFLRLALQDPTPDRKFFRRGWVTYDRTVNIKEICWNLNNIRLHDCDIGAIVNRELTQRIRPVMVLANHKPVMRHDIKIASRLVAKFDKRHNLWQREDGKDT-TNPMSSNNPLLANITEYLVDEGSYXXXXXXXXXXXXXXXXTVTGSDPSNIKVEVDDKLAAVLDRLILYLRFVHSFDYYSTTEYQIEDEMPHRCGILHARGAHIHVDKPLTQKEVEEYIKSFEMKAELILNSVELLTIDEAKKLGYKTLDESVDVFIAENTQEISKDKWLCPLSGKKFKGPDFVQKHILNKHMDKVELVKQNTEFFNNYLLDPKRPQLPE-HPSNRPG 2170
+PR LHKT S+F+RN+ PN+ R+EI +L K Y GF+R+AL +P P+R+FFRRGWVT+DR+VNIKEICWNL NIRL +C++ VNR+LT+R+R + + HK ++R+DIK+A++L+ D R LW E G + S NP+L NIT+YL++E S EEE LLG + + E +P+ I VE D+KL VLD+L+LYLR VHS DYY+T EY EDEMP+RCGI+H RG ++ EV E+ K+FE K +L+ E L+ +EA+K+G K ++ V+ F+ NTQE+ KDKWLCPLSGKKFKGP+FV+KHI NKH +K+E VK+ FFNN+L D KRP LPE P+ PG
Sbjct: 43 KPRPLHKTCSLFMRNIAPNISRAEIISLCKRYPGFMRVALSEPQPERRFFRRGWVTFDRSVNIKEICWNLQNIRLRECELSPGVNRDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWASEPGTPPLPTSLPSQNPILKNITDYLIEEVSAEEEELLGSSGGAPPEEPPKEGNPAEINVERDEKLIKVLDKLLLYLRIVHSLDYYNTCEYPNEDEMPNRCGIIHVRGP--MPPNRISHGEVLEWQKTFEEKLTPLLSVRESLSEEEAQKMGRKDPEQEVEKFVTSNTQELGKDKWLCPLSGKKFKGPEFVRKHIFNKHAEKIEEVKKEVAFFNNFLTDAKRPALPEIKPAQPPG 402
BLAST of serrate RNA effector molecule vs. Ensembl Human
Match: SRRT (serrate, RNA effector molecule [Source:HGNC Symbol;Acc:HGNC:24101]) HSP 1 Score: 369.392 bits (947), Expect = 3.041e-113 Identity = 190/362 (52.49%), Postives = 256/362 (70.72%), Query Frame = 2
Query: 1091 EPRALHKTFSIFLRNLHPNVLRSEIEALVKPYSGFLRLALQDPTPDRKFFRRGWVTYDRTVNIKEICWNLNNIRLHDCDIGAIVNRELTQRIRPVMVLANHKPVMRHDIKIASRLVAKFDKRHNLWQREDGKDT-TNPMSSNNPLLANITEYLVDEGSYXXXXXXXXXXXXXXXXTVTGSDPSNIKVEVDDKLAAVLDRLILYLRFVHSFDYYSTTEYQIEDEMPHRCGILHARGAHIHVDKPLTQKEVEEYIKSFEMKAELILNSVELLTIDEAKKLGYKTLDESVDVFIAENTQEISKDKWLCPLSGKKFKGPDFVQKHILNKHMDKVELVKQNTEFFNNYLLDPKRPQLPE-HPSNRPG 2170
+PR LHKT S+F+RN+ PN+ R+EI +L K Y GF+R+AL +P P+R+FFRRGWVT+DR+VNIKEICWNL NIRL +C++ VNR+LT+R+R + + HK ++R+DIK+A++L+ D R LW E G + S NP+L NIT+YL++E S EEE LLG + + E +P+ I VE D+KL VLD+L+LYLR VHS DYY+T EY EDEMP+RCGI+H RG ++ EV E+ K+FE K +L+ E L+ +EA+K+G K ++ V+ F+ NTQE+ KDKWLCPLSGKKFKGP+FV+KHI NKH +K+E VK+ FFNN+L D KRP LPE P+ PG
Sbjct: 412 KPRPLHKTCSLFMRNIAPNISRAEIISLCKRYPGFMRVALSEPQPERRFFRRGWVTFDRSVNIKEICWNLQNIRLRECELSPGVNRDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWASEPGTPPLPTSLPSQNPILKNITDYLIEEVSAEEEELLGSSGGAPPEEPPKEGNPAEINVERDEKLIKVLDKLLLYLRIVHSLDYYNTCEYPNEDEMPNRCGIIHVRGP--MPPNRISHGEVLEWQKTFEEKLTPLLSVRESLSEEEAQKMGRKDPEQEVEKFVTSNTQELGKDKWLCPLSGKKFKGPEFVRKHIFNKHAEKIEEVKKEVAFFNNFLTDAKRPALPEIKPAQPPG 771 HSP 2 Score: 113.235 bits (282), Expect = 7.595e-25 Identity = 53/122 (43.44%), Postives = 78/122 (63.93%), Query Frame = 2
Query: 518 PPMLLFKHFLQQQDDDIEMDQAMKKYNEYKDSFVTKQLKAFFDSHSNQEWFREKYSPQFVEKRKVELEKNIQLRKEIFTYLHERNWMDNIKIHVDENDSIVRLMDAVVILLEGGNAHDLTIL 883
P M FK FL DD ++ +A+K+YN+YK F +Q++ FF +H ++EWFR KY P V KR+ E +Q R +F L E W DN+ + +D+ D+IV+++DA VI +EGG +DL IL
Sbjct: 147 PVMKTFKEFLLSLDDSVDETEAVKRYNDYKLDFRRQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVFLSLMETGWFDNLLLDIDKADAIVKMLDAAVIKMEGGTENDLRIL 268
BLAST of serrate RNA effector molecule vs. Ensembl Human
Match: SRRT (serrate, RNA effector molecule [Source:HGNC Symbol;Acc:HGNC:24101]) HSP 1 Score: 369.392 bits (947), Expect = 3.111e-113 Identity = 190/362 (52.49%), Postives = 256/362 (70.72%), Query Frame = 2
Query: 1091 EPRALHKTFSIFLRNLHPNVLRSEIEALVKPYSGFLRLALQDPTPDRKFFRRGWVTYDRTVNIKEICWNLNNIRLHDCDIGAIVNRELTQRIRPVMVLANHKPVMRHDIKIASRLVAKFDKRHNLWQREDGKDT-TNPMSSNNPLLANITEYLVDEGSYXXXXXXXXXXXXXXXXTVTGSDPSNIKVEVDDKLAAVLDRLILYLRFVHSFDYYSTTEYQIEDEMPHRCGILHARGAHIHVDKPLTQKEVEEYIKSFEMKAELILNSVELLTIDEAKKLGYKTLDESVDVFIAENTQEISKDKWLCPLSGKKFKGPDFVQKHILNKHMDKVELVKQNTEFFNNYLLDPKRPQLPE-HPSNRPG 2170
+PR LHKT S+F+RN+ PN+ R+EI +L K Y GF+R+AL +P P+R+FFRRGWVT+DR+VNIKEICWNL NIRL +C++ VNR+LT+R+R + + HK ++R+DIK+A++L+ D R LW E G + S NP+L NIT+YL++E S EEE LLG + + E +P+ I VE D+KL VLD+L+LYLR VHS DYY+T EY EDEMP+RCGI+H RG ++ EV E+ K+FE K +L+ E L+ +EA+K+G K ++ V+ F+ NTQE+ KDKWLCPLSGKKFKGP+FV+KHI NKH +K+E VK+ FFNN+L D KRP LPE P+ PG
Sbjct: 413 KPRPLHKTCSLFMRNIAPNISRAEIISLCKRYPGFMRVALSEPQPERRFFRRGWVTFDRSVNIKEICWNLQNIRLRECELSPGVNRDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWASEPGTPPLPTSLPSQNPILKNITDYLIEEVSAEEEELLGSSGGAPPEEPPKEGNPAEINVERDEKLIKVLDKLLLYLRIVHSLDYYNTCEYPNEDEMPNRCGIIHVRGP--MPPNRISHGEVLEWQKTFEEKLTPLLSVRESLSEEEAQKMGRKDPEQEVEKFVTSNTQELGKDKWLCPLSGKKFKGPEFVRKHIFNKHAEKIEEVKKEVAFFNNFLTDAKRPALPEIKPAQPPG 772 HSP 2 Score: 113.235 bits (282), Expect = 7.605e-25 Identity = 53/122 (43.44%), Postives = 78/122 (63.93%), Query Frame = 2
Query: 518 PPMLLFKHFLQQQDDDIEMDQAMKKYNEYKDSFVTKQLKAFFDSHSNQEWFREKYSPQFVEKRKVELEKNIQLRKEIFTYLHERNWMDNIKIHVDENDSIVRLMDAVVILLEGGNAHDLTIL 883
P M FK FL DD ++ +A+K+YN+YK F +Q++ FF +H ++EWFR KY P V KR+ E +Q R +F L E W DN+ + +D+ D+IV+++DA VI +EGG +DL IL
Sbjct: 147 PVMKTFKEFLLSLDDSVDETEAVKRYNDYKLDFRRQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVFLSLMETGWFDNLLLDIDKADAIVKMLDAAVIKMEGGTENDLRIL 268
BLAST of serrate RNA effector molecule vs. Ensembl Human
Match: SRRT (serrate, RNA effector molecule [Source:HGNC Symbol;Acc:HGNC:24101]) HSP 1 Score: 369.392 bits (947), Expect = 3.348e-113 Identity = 190/362 (52.49%), Postives = 256/362 (70.72%), Query Frame = 2
Query: 1091 EPRALHKTFSIFLRNLHPNVLRSEIEALVKPYSGFLRLALQDPTPDRKFFRRGWVTYDRTVNIKEICWNLNNIRLHDCDIGAIVNRELTQRIRPVMVLANHKPVMRHDIKIASRLVAKFDKRHNLWQREDGKDT-TNPMSSNNPLLANITEYLVDEGSYXXXXXXXXXXXXXXXXTVTGSDPSNIKVEVDDKLAAVLDRLILYLRFVHSFDYYSTTEYQIEDEMPHRCGILHARGAHIHVDKPLTQKEVEEYIKSFEMKAELILNSVELLTIDEAKKLGYKTLDESVDVFIAENTQEISKDKWLCPLSGKKFKGPDFVQKHILNKHMDKVELVKQNTEFFNNYLLDPKRPQLPE-HPSNRPG 2170
+PR LHKT S+F+RN+ PN+ R+EI +L K Y GF+R+AL +P P+R+FFRRGWVT+DR+VNIKEICWNL NIRL +C++ VNR+LT+R+R + + HK ++R+DIK+A++L+ D R LW E G + S NP+L NIT+YL++E S EEE LLG + + E +P+ I VE D+KL VLD+L+LYLR VHS DYY+T EY EDEMP+RCGI+H RG ++ EV E+ K+FE K +L+ E L+ +EA+K+G K ++ V+ F+ NTQE+ KDKWLCPLSGKKFKGP+FV+KHI NKH +K+E VK+ FFNN+L D KRP LPE P+ PG
Sbjct: 412 KPRPLHKTCSLFMRNIAPNISRAEIISLCKRYPGFMRVALSEPQPERRFFRRGWVTFDRSVNIKEICWNLQNIRLRECELSPGVNRDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWASEPGTPPLPTSLPSQNPILKNITDYLIEEVSAEEEELLGSSGGAPPEEPPKEGNPAEINVERDEKLIKVLDKLLLYLRIVHSLDYYNTCEYPNEDEMPNRCGIIHVRGP--MPPNRISHGEVLEWQKTFEEKLTPLLSVRESLSEEEAQKMGRKDPEQEVEKFVTSNTQELGKDKWLCPLSGKKFKGPEFVRKHIFNKHAEKIEEVKKEVAFFNNFLTDAKRPALPEIKPAQPPG 771 HSP 2 Score: 113.235 bits (282), Expect = 7.683e-25 Identity = 53/122 (43.44%), Postives = 78/122 (63.93%), Query Frame = 2
Query: 518 PPMLLFKHFLQQQDDDIEMDQAMKKYNEYKDSFVTKQLKAFFDSHSNQEWFREKYSPQFVEKRKVELEKNIQLRKEIFTYLHERNWMDNIKIHVDENDSIVRLMDAVVILLEGGNAHDLTIL 883
P M FK FL DD ++ +A+K+YN+YK F +Q++ FF +H ++EWFR KY P V KR+ E +Q R +F L E W DN+ + +D+ D+IV+++DA VI +EGG +DL IL
Sbjct: 147 PVMKTFKEFLLSLDDSVDETEAVKRYNDYKLDFRRQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVFLSLMETGWFDNLLLDIDKADAIVKMLDAAVIKMEGGTENDLRIL 268
BLAST of serrate RNA effector molecule vs. Ensembl Human
Match: SRRT (serrate, RNA effector molecule [Source:HGNC Symbol;Acc:HGNC:24101]) HSP 1 Score: 369.392 bits (947), Expect = 3.425e-113 Identity = 190/362 (52.49%), Postives = 256/362 (70.72%), Query Frame = 2
Query: 1091 EPRALHKTFSIFLRNLHPNVLRSEIEALVKPYSGFLRLALQDPTPDRKFFRRGWVTYDRTVNIKEICWNLNNIRLHDCDIGAIVNRELTQRIRPVMVLANHKPVMRHDIKIASRLVAKFDKRHNLWQREDGKDT-TNPMSSNNPLLANITEYLVDEGSYXXXXXXXXXXXXXXXXTVTGSDPSNIKVEVDDKLAAVLDRLILYLRFVHSFDYYSTTEYQIEDEMPHRCGILHARGAHIHVDKPLTQKEVEEYIKSFEMKAELILNSVELLTIDEAKKLGYKTLDESVDVFIAENTQEISKDKWLCPLSGKKFKGPDFVQKHILNKHMDKVELVKQNTEFFNNYLLDPKRPQLPE-HPSNRPG 2170
+PR LHKT S+F+RN+ PN+ R+EI +L K Y GF+R+AL +P P+R+FFRRGWVT+DR+VNIKEICWNL NIRL +C++ VNR+LT+R+R + + HK ++R+DIK+A++L+ D R LW E G + S NP+L NIT+YL++E S EEE LLG + + E +P+ I VE D+KL VLD+L+LYLR VHS DYY+T EY EDEMP+RCGI+H RG ++ EV E+ K+FE K +L+ E L+ +EA+K+G K ++ V+ F+ NTQE+ KDKWLCPLSGKKFKGP+FV+KHI NKH +K+E VK+ FFNN+L D KRP LPE P+ PG
Sbjct: 413 KPRPLHKTCSLFMRNIAPNISRAEIISLCKRYPGFMRVALSEPQPERRFFRRGWVTFDRSVNIKEICWNLQNIRLRECELSPGVNRDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWASEPGTPPLPTSLPSQNPILKNITDYLIEEVSAEEEELLGSSGGAPPEEPPKEGNPAEINVERDEKLIKVLDKLLLYLRIVHSLDYYNTCEYPNEDEMPNRCGIIHVRGP--MPPNRISHGEVLEWQKTFEEKLTPLLSVRESLSEEEAQKMGRKDPEQEVEKFVTSNTQELGKDKWLCPLSGKKFKGPEFVRKHIFNKHAEKIEEVKKEVAFFNNFLTDAKRPALPEIKPAQPPG 772 HSP 2 Score: 113.235 bits (282), Expect = 7.694e-25 Identity = 53/122 (43.44%), Postives = 78/122 (63.93%), Query Frame = 2
Query: 518 PPMLLFKHFLQQQDDDIEMDQAMKKYNEYKDSFVTKQLKAFFDSHSNQEWFREKYSPQFVEKRKVELEKNIQLRKEIFTYLHERNWMDNIKIHVDENDSIVRLMDAVVILLEGGNAHDLTIL 883
P M FK FL DD ++ +A+K+YN+YK F +Q++ FF +H ++EWFR KY P V KR+ E +Q R +F L E W DN+ + +D+ D+IV+++DA VI +EGG +DL IL
Sbjct: 147 PVMKTFKEFLLSLDDSVDETEAVKRYNDYKLDFRRQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVFLSLMETGWFDNLLLDIDKADAIVKMLDAAVIKMEGGTENDLRIL 268
BLAST of serrate RNA effector molecule vs. Ensembl Celegans
Match: E01A2.2 (Serrate RNA effector molecule homolog [Source:UniProtKB/Swiss-Prot;Acc:Q966L5]) HSP 1 Score: 355.14 bits (910), Expect = 6.198e-110 Identity = 215/581 (37.01%), Postives = 326/581 (56.11%), Query Frame = 2
Query: 479 IPKSDDTPNYPTQP------PMLLFKHFLQQQDDDIEMDQAMKKYNEYKDSFVTKQLKAFFDSHSNQEWFREKYSPQFVEK-RKVELEKNIQLRKEIFTYLHERNWMDNIKIHVDENDSIVRLMDAVVILLEGGNAHDLTILDSKRYRSESPNDSHILEDVVVKSPEKVTSSEGIEVVNKEIIEPDDKKFXXXXXXXXXXXXKFEKKSELQEPRA-LHKTFSIFLRNLHPNVLRSEIEALVKPYSGFLRLALQDPTPDRKFFRRGWVTYDRTVNIKEICWNLNNIRLHDCDIGAIVNRELTQRIRPVMVLANHKPVMRHDIKIASRLVAKFDKRHNLWQREDGKDTTNPM----------SSNNPLLANITEYLVDEGSYXXXXXXXXXXXXXXXXTVTGSDPS-NIKVEVDDKLAAVLDRLILYLRFVHSFDYYSTTEYQIEDEMPHRCGILHAR-----GAHIHVDKP----LTQKEVEEYIKSFEMKAELILNSVELLTIDEAKKLGYKTLDESVDVFIAENTQEISKDKWLCPLSGKKFKGPDFVQKHILNKHMDKVELVKQNTEFFNNYLLDPKRP 2137
+ +S + + PT+ P+ FK FL Q+DDI + A+KKYNEYK QL+ FF +H ++EWFR KY P +K R+ LE N+Q R ++F L E+ + + + ++I+R++D+VV+ LE G +L + +++ ES D +K E +E KE EP+ K+ E + E E E +E + +H+T S+FLRN+ P + E+E L K GFLRLAL D +RKF+RRGW T+ R +NIKEICW LN RL + D+ AI+NR++T+R+R +A+HK V +D+K+A +L +DK+ L+ D D M +S NPL+ + + ++ + L ++ G P+ I+ E DD + LD LI+YLR VHS D+Y+ Y ED MP+RCG++H R G I D+ + QK V ++I F + E L + ++ +E +K+G K ++ V+ FI +NT E++KDKWLCPLSGKKFKGP+F++KH+ +KH DK+E + +FFNNYL D +RP
Sbjct: 63 VSRSGNGSDLPTESDSIYSGPLQTFKKFLTSQEDDISEEDAIKKYNEYKTEHRKHQLERFFRAHKDEEWFRLKYKPDDAKKLREAHLE-NVQKRLQVFNELKEQGQFNKFSLDFGDAEAIIRMLDSVVVKLENGTEDELKAVLAQKLEDESLAD--------IKKDENGNGTE----QPKE--EPEVKQ--ESGATEELEEGAIEDGTEKSSNKVNIHRTCSVFLRNIPPGLTYEELEGLCKKSPGFLRLALTDGIAERKFYRRGWATFKRDINIKEICWALNAHRLRETDLNAIINRDITRRVRTNNGIASHKQVAINDLKLAVKLTVLYDKKIGLFNAADEADADREMDIRMGVDLVAASTNPLIKEVKSLV----PHDVLNDISEEEAELLGVSNGGEAPAEKIRFERDDNILKALDLLIVYLRIVHSIDFYNHGHYAQEDSMPNRCGLIHVRGQPPSGVSITTDEDGALVVPQKFVNDFISGFNSRIEKGLIEKQYVSEEELEKMGKKDGEKEVEAFIQKNTVELAKDKWLCPLSGKKFKGPEFIRKHLQSKHEDKLEEARAEADFFNNYLADAQRP 622
BLAST of serrate RNA effector molecule vs. Ensembl Celegans
Match: E01A2.2 (Serrate RNA effector molecule homolog [Source:UniProtKB/Swiss-Prot;Acc:Q966L5]) HSP 1 Score: 280.026 bits (715), Expect = 6.522e-84 Identity = 148/365 (40.55%), Postives = 218/365 (59.73%), Query Frame = 2
Query: 1103 LHKTFSIFLRNLHPNVLRSEIEALVKPYSGFLRLALQDPTPDRKFFRRGWVTYDRTVNIKEICWNLNNIRLHDCDIGAIVNRELTQRIRPVMVLANHKPVMRHDIKIASRLVAKFDKRHNLWQREDGKDTTNPM----------SSNNPLLANITEYLVDEGSYXXXXXXXXXXXXXXXXTVTGSDPS-NIKVEVDDKLAAVLDRLILYLRFVHSFDYYSTTEYQIEDEMPHRCGILHAR-----GAHIHVDKP----LTQKEVEEYIKSFEMKAELILNSVELLTIDEAKKLGYKTLDESVDVFIAENTQEISKDKWLCPLSGKKFKGPDFVQKHILNKHMDKVELVKQNTEFFNNYLLDPKRP 2137
+H+T S+FLRN+ P + E+E L K GFLRLAL D +RKF+RRGW T+ R +NIKEICW LN RL + D+ AI+NR++T+R+R +A+HK V +D+K+A +L +DK+ L+ D D M +S NPL+ + + ++ + L ++ G P+ I+ E DD + LD LI+YLR VHS D+Y+ Y ED MP+RCG++H R G I D+ + QK V ++I F + E L + ++ +E +K+G K ++ V+ FI +NT E++KDKWLCPLSGKKFKGP+F++KH+ +KH DK+E + +FFNNYL D +RP
Sbjct: 79 IHRTCSVFLRNIPPGLTYEELEGLCKKSPGFLRLALTDGIAERKFYRRGWATFKRDINIKEICWALNAHRLRETDLNAIINRDITRRVRTNNGIASHKQVAINDLKLAVKLTVLYDKKIGLFNAADEADADREMDIRMGVDLVAASTNPLIKEVKSLV----PHDVLNDISEEEAELLGVSNGGEAPAEKIRFERDDNILKALDLLIVYLRIVHSIDFYNHGHYAQEDSMPNRCGLIHVRGQPPSGVSITTDEDGALVVPQKFVNDFISGFNSRIEKGLIEKQYVSEEELEKMGKKDGEKEVEAFIQKNTVELAKDKWLCPLSGKKFKGPEFIRKHLQSKHEDKLEEARAEADFFNNYLADAQRP 439
BLAST of serrate RNA effector molecule vs. Ensembl Fly
Match: Ars2 (gene:FBgn0033062 transcript:FBtr0310665) HSP 1 Score: 368.237 bits (944), Expect = 1.792e-112 Identity = 185/377 (49.07%), Postives = 249/377 (66.05%), Query Frame = 2
Query: 1091 EPRALHKTFSIFLRNLHPNVLRSEIEALVKPYSGFLRLALQDPTPDRKFFRRGWVTYDRTVNIKEICWNLNNIRLHDCDIGAIVNRELTQRIRPVMVLANHKPVMRHDIKIASRLVAKFDKRHNLWQR---------------EDGKDTTNPMSSNNPLLANITEYLVDEGSYXXXXXXXXXXXXXXXXTVTGSDPSNIKVEVDDKLAAVLDRLILYLRFVHSFDYYSTTEYQIEDEMPHRCGILHARG-AHIHVDKPLTQKEVEEYIKSFEMKAELILNSVELLTIDEAKKLGYKTLDESVDVFIAENTQEISKDKWLCPLSGKKFKGPDFVQKHILNKHMDKVELVKQNTEFFNNYLLDPKRPQLPEHP--SNRP 2167
+PRALH+T SIFLRNL P++ RSEIEA+ +SG+LR+A+ DP +R+++RRGW+T+ R VNIKEICW LNN RL DC++GAIVNR+L++R+RP + HK V+R DIK+ +++ D++ LW E+G +T +S NP+L NIT+YL+ L LT D +E D++L +VLDRL+LYLR VHS DYY+ EY EDEMP+RCGI+HARG + V T +V+EYIK +E K + L L+ +E K LG K + V+ F+ NTQE++KDKWLCPLSGKKFKGP+F++KHI NKH +KV+ V++ ++FNNYL DPKRPQLPEHP S RP
Sbjct: 503 QPRALHRTSSIFLRNLAPSITRSEIEAVCNRFSGYLRVAIADPLVERRWYRRGWITFMRDVNIKEICWGLNNQRLRDCEMGAIVNRDLSRRVRPANGITAHKQVVRSDIKLCAKIALNLDEKFRLWAEGPKDDSNSARANESSENGSGSTYGFNSQNPVLQNITDYLI--------EEASAEEEELLGLTGENKDTEGEPIERDEQLISVLDRLVLYLRIVHSVDYYNHCEYPYEDEMPNRCGIIHARGPPPVRV----TNNDVQEYIKIYESKLQQFLTKTVPLSDEEIKNLGAKDAETEVEKFVQANTQELAKDKWLCPLSGKKFKGPEFIRKHIFNKHEEKVDEVRKEVQYFNNYLRDPKRPQLPEHPGTSKRP 867 HSP 2 Score: 108.612 bits (270), Expect = 1.048e-23 Identity = 52/127 (40.94%), Postives = 76/127 (59.84%), Query Frame = 2
Query: 512 TQPPMLLFKHFLQQQDDDIEMDQAMKKYNEYKDSFVTKQLKAFFDSHSNQEWFREKYSPQFVEKRKVELEKNIQLRKEIFTYLHERNWMDNIKIHVDENDSIVRLMDAVVILLEGGNAHDLTILDSK 892
TQP ML K FL QD++I + M+KY EYK F +QL FF +H ++EWF+ KY P+ KR E +Q R ++F L E + ++K+ + D+++R++D VI LEGG DL +LD K
Sbjct: 147 TQPAMLNLKQFLDTQDENISDSEVMRKYTEYKTDFKRQQLNEFFVAHKDEEWFKNKYHPEDSVKRSEEQRGFLQRRTDVFMELLENGTIGSVKVDSSQADALIRVLDTCVIKLEGGTDEDLKVLDEK 273
BLAST of serrate RNA effector molecule vs. Ensembl Fly
Match: Ars2 (gene:FBgn0033062 transcript:FBtr0310667) HSP 1 Score: 368.237 bits (944), Expect = 1.911e-112 Identity = 185/377 (49.07%), Postives = 249/377 (66.05%), Query Frame = 2
Query: 1091 EPRALHKTFSIFLRNLHPNVLRSEIEALVKPYSGFLRLALQDPTPDRKFFRRGWVTYDRTVNIKEICWNLNNIRLHDCDIGAIVNRELTQRIRPVMVLANHKPVMRHDIKIASRLVAKFDKRHNLW---------------QREDGKDTTNPMSSNNPLLANITEYLVDEGSYXXXXXXXXXXXXXXXXTVTGSDPSNIKVEVDDKLAAVLDRLILYLRFVHSFDYYSTTEYQIEDEMPHRCGILHARG-AHIHVDKPLTQKEVEEYIKSFEMKAELILNSVELLTIDEAKKLGYKTLDESVDVFIAENTQEISKDKWLCPLSGKKFKGPDFVQKHILNKHMDKVELVKQNTEFFNNYLLDPKRPQLPEHP--SNRP 2167
+PRALH+T SIFLRNL P++ RSEIEA+ +SG+LR+A+ DP +R+++RRGW+T+ R VNIKEICW LNN RL DC++GAIVNR+L++R+RP + HK V+R DIK+ +++ D++ LW E+G +T +S NP+L NIT+YL+ L LT D +E D++L +VLDRL+LYLR VHS DYY+ EY EDEMP+RCGI+HARG + V T +V+EYIK +E K + L L+ +E K LG K + V+ F+ NTQE++KDKWLCPLSGKKFKGP+F++KHI NKH +KV+ V++ ++FNNYL DPKRPQLPEHP S RP
Sbjct: 507 QPRALHRTSSIFLRNLAPSITRSEIEAVCNRFSGYLRVAIADPLVERRWYRRGWITFMRDVNIKEICWGLNNQRLRDCEMGAIVNRDLSRRVRPANGITAHKQVVRSDIKLCAKIALNLDEKFRLWAEGPKDDSNSARANESSENGSGSTYGFNSQNPVLQNITDYLI--------EEASAEEEELLGLTGENKDTEGEPIERDEQLISVLDRLVLYLRIVHSVDYYNHCEYPYEDEMPNRCGIIHARGPPPVRV----TNNDVQEYIKIYESKLQQFLTKTVPLSDEEIKNLGAKDAETEVEKFVQANTQELAKDKWLCPLSGKKFKGPEFIRKHIFNKHEEKVDEVRKEVQYFNNYLRDPKRPQLPEHPGTSKRP 871 HSP 2 Score: 108.612 bits (270), Expect = 1.117e-23 Identity = 52/127 (40.94%), Postives = 76/127 (59.84%), Query Frame = 2
Query: 512 TQPPMLLFKHFLQQQDDDIEMDQAMKKYNEYKDSFVTKQLKAFFDSHSNQEWFREKYSPQFVEKRKVELEKNIQLRKEIFTYLHERNWMDNIKIHVDENDSIVRLMDAVVILLEGGNAHDLTILDSK 892
TQP ML K FL QD++I + M+KY EYK F +QL FF +H ++EWF+ KY P+ KR E +Q R ++F L E + ++K+ + D+++R++D VI LEGG DL +LD K
Sbjct: 151 TQPAMLNLKQFLDTQDENISDSEVMRKYTEYKTDFKRQQLNEFFVAHKDEEWFKNKYHPEDSVKRSEEQRGFLQRRTDVFMELLENGTIGSVKVDSSQADALIRVLDTCVIKLEGGTDEDLKVLDEK 277
BLAST of serrate RNA effector molecule vs. Ensembl Fly
Match: Ars2 (gene:FBgn0033062 transcript:FBtr0086020) HSP 1 Score: 367.851 bits (943), Expect = 2.924e-112 Identity = 185/377 (49.07%), Postives = 249/377 (66.05%), Query Frame = 2
Query: 1091 EPRALHKTFSIFLRNLHPNVLRSEIEALVKPYSGFLRLALQDPTPDRKFFRRGWVTYDRTVNIKEICWNLNNIRLHDCDIGAIVNRELTQRIRPVMVLANHKPVMRHDIKIASRLVAKFDKRHNLWQR---------------EDGKDTTNPMSSNNPLLANITEYLVDEGSYXXXXXXXXXXXXXXXXTVTGSDPSNIKVEVDDKLAAVLDRLILYLRFVHSFDYYSTTEYQIEDEMPHRCGILHARG-AHIHVDKPLTQKEVEEYIKSFEMKAELILNSVELLTIDEAKKLGYKTLDESVDVFIAENTQEISKDKWLCPLSGKKFKGPDFVQKHILNKHMDKVELVKQNTEFFNNYLLDPKRPQLPEHP--SNRP 2167
+PRALH+T SIFLRNL P++ RSEIEA+ +SG+LR+A+ DP +R+++RRGW+T+ R VNIKEICW LNN RL DC++GAIVNR+L++R+RP + HK V+R DIK+ +++ D++ LW E+G +T +S NP+L NIT+YL+ L LT D +E D++L +VLDRL+LYLR VHS DYY+ EY EDEMP+RCGI+HARG + V T +V+EYIK +E K + L L+ +E K LG K + V+ F+ NTQE++KDKWLCPLSGKKFKGP+F++KHI NKH +KV+ V++ ++FNNYL DPKRPQLPEHP S RP
Sbjct: 507 QPRALHRTSSIFLRNLAPSITRSEIEAVCNRFSGYLRVAIADPLVERRWYRRGWITFMRDVNIKEICWGLNNQRLRDCEMGAIVNRDLSRRVRPANGITAHKQVVRSDIKLCAKIALNLDEKFRLWAEGPKDDSNSARANESSENGSGSTYGFNSQNPVLQNITDYLI--------EEASAEEEELLGLTGENKDTEGEPIERDEQLISVLDRLVLYLRIVHSVDYYNHCEYPYEDEMPNRCGIIHARGPPPVRV----TNNDVQEYIKIYESKLQQFLTKTVPLSDEEIKNLGAKDAETEVEKFVQANTQELAKDKWLCPLSGKKFKGPEFIRKHIFNKHEEKVDEVRKEVQYFNNYLRDPKRPQLPEHPGTSKRP 871 HSP 2 Score: 108.227 bits (269), Expect = 1.309e-23 Identity = 52/127 (40.94%), Postives = 76/127 (59.84%), Query Frame = 2
Query: 512 TQPPMLLFKHFLQQQDDDIEMDQAMKKYNEYKDSFVTKQLKAFFDSHSNQEWFREKYSPQFVEKRKVELEKNIQLRKEIFTYLHERNWMDNIKIHVDENDSIVRLMDAVVILLEGGNAHDLTILDSK 892
TQP ML K FL QD++I + M+KY EYK F +QL FF +H ++EWF+ KY P+ KR E +Q R ++F L E + ++K+ + D+++R++D VI LEGG DL +LD K
Sbjct: 151 TQPAMLNLKQFLDTQDENISDSEVMRKYTEYKTDFKRQQLNEFFVAHKDEEWFKNKYHPEDSVKRSEEQRGFLQRRTDVFMELLENGTIGSVKVDSSQADALIRVLDTCVIKLEGGTDEDLKVLDEK 277
BLAST of serrate RNA effector molecule vs. Ensembl Fly
Match: Ars2 (gene:FBgn0033062 transcript:FBtr0086021) HSP 1 Score: 367.851 bits (943), Expect = 2.924e-112 Identity = 185/377 (49.07%), Postives = 249/377 (66.05%), Query Frame = 2
Query: 1091 EPRALHKTFSIFLRNLHPNVLRSEIEALVKPYSGFLRLALQDPTPDRKFFRRGWVTYDRTVNIKEICWNLNNIRLHDCDIGAIVNRELTQRIRPVMVLANHKPVMRHDIKIASRLVAKFDKRHNLWQR---------------EDGKDTTNPMSSNNPLLANITEYLVDEGSYXXXXXXXXXXXXXXXXTVTGSDPSNIKVEVDDKLAAVLDRLILYLRFVHSFDYYSTTEYQIEDEMPHRCGILHARG-AHIHVDKPLTQKEVEEYIKSFEMKAELILNSVELLTIDEAKKLGYKTLDESVDVFIAENTQEISKDKWLCPLSGKKFKGPDFVQKHILNKHMDKVELVKQNTEFFNNYLLDPKRPQLPEHP--SNRP 2167
+PRALH+T SIFLRNL P++ RSEIEA+ +SG+LR+A+ DP +R+++RRGW+T+ R VNIKEICW LNN RL DC++GAIVNR+L++R+RP + HK V+R DIK+ +++ D++ LW E+G +T +S NP+L NIT+YL+ L LT D +E D++L +VLDRL+LYLR VHS DYY+ EY EDEMP+RCGI+HARG + V T +V+EYIK +E K + L L+ +E K LG K + V+ F+ NTQE++KDKWLCPLSGKKFKGP+F++KHI NKH +KV+ V++ ++FNNYL DPKRPQLPEHP S RP
Sbjct: 507 QPRALHRTSSIFLRNLAPSITRSEIEAVCNRFSGYLRVAIADPLVERRWYRRGWITFMRDVNIKEICWGLNNQRLRDCEMGAIVNRDLSRRVRPANGITAHKQVVRSDIKLCAKIALNLDEKFRLWAEGPKDDSNSARANESSENGSGSTYGFNSQNPVLQNITDYLI--------EEASAEEEELLGLTGENKDTEGEPIERDEQLISVLDRLVLYLRIVHSVDYYNHCEYPYEDEMPNRCGIIHARGPPPVRV----TNNDVQEYIKIYESKLQQFLTKTVPLSDEEIKNLGAKDAETEVEKFVQANTQELAKDKWLCPLSGKKFKGPEFIRKHIFNKHEEKVDEVRKEVQYFNNYLRDPKRPQLPEHPGTSKRP 871 HSP 2 Score: 108.227 bits (269), Expect = 1.309e-23 Identity = 52/127 (40.94%), Postives = 76/127 (59.84%), Query Frame = 2
Query: 512 TQPPMLLFKHFLQQQDDDIEMDQAMKKYNEYKDSFVTKQLKAFFDSHSNQEWFREKYSPQFVEKRKVELEKNIQLRKEIFTYLHERNWMDNIKIHVDENDSIVRLMDAVVILLEGGNAHDLTILDSK 892
TQP ML K FL QD++I + M+KY EYK F +QL FF +H ++EWF+ KY P+ KR E +Q R ++F L E + ++K+ + D+++R++D VI LEGG DL +LD K
Sbjct: 151 TQPAMLNLKQFLDTQDENISDSEVMRKYTEYKTDFKRQQLNEFFVAHKDEEWFKNKYHPEDSVKRSEEQRGFLQRRTDVFMELLENGTIGSVKVDSSQADALIRVLDTCVIKLEGGTDEDLKVLDEK 277
BLAST of serrate RNA effector molecule vs. Ensembl Fly
Match: Ars2 (gene:FBgn0033062 transcript:FBtr0086018) HSP 1 Score: 367.851 bits (943), Expect = 2.924e-112 Identity = 185/377 (49.07%), Postives = 249/377 (66.05%), Query Frame = 2
Query: 1091 EPRALHKTFSIFLRNLHPNVLRSEIEALVKPYSGFLRLALQDPTPDRKFFRRGWVTYDRTVNIKEICWNLNNIRLHDCDIGAIVNRELTQRIRPVMVLANHKPVMRHDIKIASRLVAKFDKRHNLWQR---------------EDGKDTTNPMSSNNPLLANITEYLVDEGSYXXXXXXXXXXXXXXXXTVTGSDPSNIKVEVDDKLAAVLDRLILYLRFVHSFDYYSTTEYQIEDEMPHRCGILHARG-AHIHVDKPLTQKEVEEYIKSFEMKAELILNSVELLTIDEAKKLGYKTLDESVDVFIAENTQEISKDKWLCPLSGKKFKGPDFVQKHILNKHMDKVELVKQNTEFFNNYLLDPKRPQLPEHP--SNRP 2167
+PRALH+T SIFLRNL P++ RSEIEA+ +SG+LR+A+ DP +R+++RRGW+T+ R VNIKEICW LNN RL DC++GAIVNR+L++R+RP + HK V+R DIK+ +++ D++ LW E+G +T +S NP+L NIT+YL+ L LT D +E D++L +VLDRL+LYLR VHS DYY+ EY EDEMP+RCGI+HARG + V T +V+EYIK +E K + L L+ +E K LG K + V+ F+ NTQE++KDKWLCPLSGKKFKGP+F++KHI NKH +KV+ V++ ++FNNYL DPKRPQLPEHP S RP
Sbjct: 507 QPRALHRTSSIFLRNLAPSITRSEIEAVCNRFSGYLRVAIADPLVERRWYRRGWITFMRDVNIKEICWGLNNQRLRDCEMGAIVNRDLSRRVRPANGITAHKQVVRSDIKLCAKIALNLDEKFRLWAEGPKDDSNSARANESSENGSGSTYGFNSQNPVLQNITDYLI--------EEASAEEEELLGLTGENKDTEGEPIERDEQLISVLDRLVLYLRIVHSVDYYNHCEYPYEDEMPNRCGIIHARGPPPVRV----TNNDVQEYIKIYESKLQQFLTKTVPLSDEEIKNLGAKDAETEVEKFVQANTQELAKDKWLCPLSGKKFKGPEFIRKHIFNKHEEKVDEVRKEVQYFNNYLRDPKRPQLPEHPGTSKRP 871 HSP 2 Score: 108.227 bits (269), Expect = 1.309e-23 Identity = 52/127 (40.94%), Postives = 76/127 (59.84%), Query Frame = 2
Query: 512 TQPPMLLFKHFLQQQDDDIEMDQAMKKYNEYKDSFVTKQLKAFFDSHSNQEWFREKYSPQFVEKRKVELEKNIQLRKEIFTYLHERNWMDNIKIHVDENDSIVRLMDAVVILLEGGNAHDLTILDSK 892
TQP ML K FL QD++I + M+KY EYK F +QL FF +H ++EWF+ KY P+ KR E +Q R ++F L E + ++K+ + D+++R++D VI LEGG DL +LD K
Sbjct: 151 TQPAMLNLKQFLDTQDENISDSEVMRKYTEYKTDFKRQQLNEFFVAHKDEEWFKNKYHPEDSVKRSEEQRGFLQRRTDVFMELLENGTIGSVKVDSSQADALIRVLDTCVIKLEGGTDEDLKVLDEK 277
BLAST of serrate RNA effector molecule vs. Ensembl Zebrafish
Match: srrt (serrate RNA effector molecule homolog (Arabidopsis) [Source:NCBI gene;Acc:192311]) HSP 1 Score: 362.459 bits (929), Expect = 1.375e-110 Identity = 184/353 (52.12%), Postives = 252/353 (71.39%), Query Frame = 2
Query: 1094 PRALHKTFSIFLRNLHPNVLRSEIEALVKPYSGFLRLALQDPTPDRKFFRRGWVTYDRTVNIKEICWNLNNIRLHDCDIGAIVNRELTQRIRPVMVLANHKPVMRHDIKIASRLVAKFDKRHNLWQREDGKDT-TNPMSSNNPLLANITEYLVDEGSYXXXXXXXXXXXXXXXXTVTGSDPSNIKVEVDDKLAAVLDRLILYLRFVHSFDYYSTTEYQIEDEMPHRCGILHARGAHIHVDKPLTQKEVEEYIKSFEMKAELILNSVELLTIDEAKKLGYKTLDESVDVFIAENTQEISKDKWLCPLSGKKFKGPDFVQKHILNKHMDKVELVKQNTEFFNNYLLDPKRPQLPE 2149
PR LH+T S+F+R++ P + ++EI AL + Y GF+R+ L +P P+R+FFRR WVT+DR VNIKEICWNL NIRL DC++ VNR+L +R+R V + HK V+R+DIK+A++L+ D R LW ++ ++T T + + NP+L NIT+YL++E S EEE LLG + E +P+ I VE D+KL VLDRL+ YLR VHS DYY+T EY EDEMP+RCGI+H RG I ++ +T +EV ++ K+FE K + + E L+ DEA K+G K ++ V+ F+ NTQE+ KDKWLCPLSGKKFKGP+FV+KHILNKH DK+E VK+ FFNN+L+D KRP +PE
Sbjct: 445 PRPLHRTCSLFMRSIAPTISKAEIVALCRRYPGFMRVCLSEPQPERRFFRRCWVTFDRGVNIKEICWNLQNIRLRDCELAPGVNRDLARRVRNVNGITQHKQVLRNDIKLAAKLIHALDDREKLWSQKPREETPTLELPAQNPILKNITDYLIEEVSAEEEELLGSAGGGDSEDGSKEGNPTEITVERDEKLVKVLDRLLFYLRIVHSIDYYNTCEYPSEDEMPNRCGIIHVRGP-IPPNR-ITLREVSDWQKTFEEKMGPLFSVKENLSEDEAAKMGRKDPEQEVEKFVVANTQELGKDKWLCPLSGKKFKGPEFVRKHILNKHGDKIEEVKKEVVFFNNFLMDAKRPCIPE 795 HSP 2 Score: 107.457 bits (267), Expect = 3.231e-23 Identity = 48/126 (38.10%), Postives = 77/126 (61.11%), Query Frame = 2
Query: 509 PTQPPMLLFKHFLQQQDDDIEMDQAMKKYNEYKDSFVTKQLKAFFDSHSNQEWFREKYSPQFVEKRKVELEKNIQLRKEIFTYLHERNWMDNIKIHVDENDSIVRLMDAVVILLEGGNAHDLTILD 886
P P M FK FL DD ++ +++K+YNEYK F +Q++ FF +H ++EWFR KY P +RK E +Q R ++ YL + NW +++ + ++ I +++DA VI +EGG +DL IL+
Sbjct: 148 PPPPVMKTFKEFLISLDDSVDETESVKRYNEYKIDFRRQQMQDFFLAHKDEEWFRSKYHPDEAGRRKAEAHSALQNRLGVYMYLMDNNWFESVSLDIERAPQITKILDAAVIKMEGGAENDLRILE 273
BLAST of serrate RNA effector molecule vs. Ensembl Zebrafish
Match: srrt (serrate RNA effector molecule homolog (Arabidopsis) [Source:NCBI gene;Acc:192311]) HSP 1 Score: 361.303 bits (926), Expect = 5.642e-110 Identity = 184/353 (52.12%), Postives = 252/353 (71.39%), Query Frame = 2
Query: 1094 PRALHKTFSIFLRNLHPNVLRSEIEALVKPYSGFLRLALQDPTPDRKFFRRGWVTYDRTVNIKEICWNLNNIRLHDCDIGAIVNRELTQRIRPVMVLANHKPVMRHDIKIASRLVAKFDKRHNLWQREDGKDT-TNPMSSNNPLLANITEYLVDEGSYXXXXXXXXXXXXXXXXTVTGSDPSNIKVEVDDKLAAVLDRLILYLRFVHSFDYYSTTEYQIEDEMPHRCGILHARGAHIHVDKPLTQKEVEEYIKSFEMKAELILNSVELLTIDEAKKLGYKTLDESVDVFIAENTQEISKDKWLCPLSGKKFKGPDFVQKHILNKHMDKVELVKQNTEFFNNYLLDPKRPQLPE 2149
PR LH+T S+F+R++ P + ++EI AL + Y GF+R+ L +P P+R+FFRR WVT+DR VNIKEICWNL NIRL DC++ VNR+L +R+R V + HK V+R+DIK+A++L+ D R LW ++ ++T T + + NP+L NIT+YL++E S EEE LLG + E +P+ I VE D+KL VLDRL+ YLR VHS DYY+T EY EDEMP+RCGI+H RG I ++ +T +EV ++ K+FE K + + E L+ DEA K+G K ++ V+ F+ NTQE+ KDKWLCPLSGKKFKGP+FV+KHILNKH DK+E VK+ FFNN+L+D KRP +PE
Sbjct: 463 PRPLHRTCSLFMRSIAPTISKAEIVALCRRYPGFMRVCLSEPQPERRFFRRCWVTFDRGVNIKEICWNLQNIRLRDCELAPGVNRDLARRVRNVNGITQHKQVLRNDIKLAAKLIHALDDREKLWSQKPREETPTLELPAQNPILKNITDYLIEEVSAEEEELLGSAGGGDSEDGSKEGNPTEITVERDEKLVKVLDRLLFYLRIVHSIDYYNTCEYPSEDEMPNRCGIIHVRGP-IPPNR-ITLREVSDWQKTFEEKMGPLFSVKENLSEDEAAKMGRKDPEQEVEKFVVANTQELGKDKWLCPLSGKKFKGPEFVRKHILNKHGDKIEEVKKEVVFFNNFLMDAKRPCIPE 813 HSP 2 Score: 107.071 bits (266), Expect = 3.849e-23 Identity = 48/126 (38.10%), Postives = 77/126 (61.11%), Query Frame = 2
Query: 509 PTQPPMLLFKHFLQQQDDDIEMDQAMKKYNEYKDSFVTKQLKAFFDSHSNQEWFREKYSPQFVEKRKVELEKNIQLRKEIFTYLHERNWMDNIKIHVDENDSIVRLMDAVVILLEGGNAHDLTILD 886
P P M FK FL DD ++ +++K+YNEYK F +Q++ FF +H ++EWFR KY P +RK E +Q R ++ YL + NW +++ + ++ I +++DA VI +EGG +DL IL+
Sbjct: 166 PPPPVMKTFKEFLISLDDSVDETESVKRYNEYKIDFRRQQMQDFFLAHKDEEWFRSKYHPDEAGRRKAEAHSALQNRLGVYMYLMDNNWFESVSLDIERAPQITKILDAAVIKMEGGAENDLRILE 291
BLAST of serrate RNA effector molecule vs. Ensembl Xenopus
Match: SRRT (serrate, RNA effector molecule [Source:HGNC Symbol;Acc:HGNC:24101]) HSP 1 Score: 344.739 bits (883), Expect = 2.117e-104 Identity = 180/373 (48.26%), Postives = 251/373 (67.29%), Query Frame = 2
Query: 1094 PRALHKTFSIFLRNLHPNVLRSEIEALVKPYSGFLRLALQDPTPDRKFFRRGWVTYDRTVNIKEICWNLNNIRLHDCDIGAIVNRELTQRIRPVMVLANHKPVMRHDIKIASRLVAKFDKRHNLWQREDGKDTTNPMSSNNPLLANITEYLVDEGSYXXXXXXXXXXXXXXXXTVTGSDPSNIKVEVDDKLAAVLDRLILYLRFVHSFDYYSTTEYQIEDEMPHRCGILHARGAHIHVDKPLTQKEVEEYIKSFEMKAELILNSVELLTIDEAKKLGYKTLDESVDVFIAENTQEISKDKWLCPLSGKKFKGPDFVQKHILNKHMDKVELVKQNTEFFNNYLLD-PKRPQLPEHPSNRPGVKTTESGEIRNEG 2209
PR LHKT SIF+RN+ PN+ ++EI AL K Y GF+R+AL +P P+R+F R+ +VT+DR+VNIKEICW++ NIRL +C++ VNR+LT R+R + + H+P++R+DIK+A+RL+ D+R LW+ E G +S+ NP+L NIT+YL+DE + EEE LL + T +P+ I VE D+KL VLD+L+ YLR VHS DYY+T EY EDEMP RCG++H RG + ++ ++ EV E+ K+FE K + E L+ +EA K+G K ++ V+ F+ NTQE+ K+KWLCPLSGKKFKGP+FV+KHI NKH +K+E VK+ F L D +RP LPE RP V T G+ G
Sbjct: 387 PRPLHKTCSIFMRNIPPNISKAEITALCKRYPGFMRVALSEPQPERRFLRKAYVTFDRSVNIKEICWSVQNIRLRECELSPGVNRDLTYRVRNINGITMHRPIVRNDIKLAARLIHALDERALLWEGEQGDQM---VSAQNPILKNITDYLIDEVNAEEEELLFSAGRTPETETPKEGNPTEISVERDEKLIKVLDKLLFYLRIVHSVDYYNTCEYPNEDEMPTRCGMMHVRGP-LPPNR-VSHGEVAEWQKTFEEKLSPLFAVRETLSEEEAVKMGKKDPEQEVEKFVTANTQELGKEKWLCPLSGKKFKGPEFVRKHIFNKHGEKIEEVKKEVAF--QTLPDRQQRPALPEVEPLRPPVGTAGQGKSLAAG 752 HSP 2 Score: 105.531 bits (262), Expect = 1.396e-22 Identity = 48/123 (39.02%), Postives = 79/123 (64.23%), Query Frame = 2
Query: 518 PPMLLFKHFLQQQDDDIEMDQAMKKYNEYKDSFVTKQLKAFFDSHSNQEWFREKYSPQFVEKRKVELEKNIQLRKEIFTYLHERNWMDNIKIHVDENDSIVRLMDAVVILLEGGNAHDLTILD 886
P M FK FL +D ++ +A+K+YN+YK F +Q++ FF +H ++EWFR KY P V K K E + ++ R F YL E +W++ +++ + ++ +I++++DA VI +EGG DL ILD
Sbjct: 147 PIMKTFKEFLLSLEDSVDETEAVKRYNDYKIDFRRQQMQEFFLAHKDEEWFRSKYHPDEVGKHKQESQAALRNRLSAFMYLMENSWLNEVQLDIAQSTAIIKVLDAAVIKMEGGTEIDLKILD 269
BLAST of serrate RNA effector molecule vs. Ensembl Xenopus
Match: SRRT (serrate, RNA effector molecule [Source:HGNC Symbol;Acc:HGNC:24101]) HSP 1 Score: 343.199 bits (879), Expect = 1.204e-103 Identity = 178/364 (48.90%), Postives = 248/364 (68.13%), Query Frame = 2
Query: 1094 PRALHKTFSIFLRNLHPNVLRSEIEALVKPYSGFLRLALQDPTPDRKFFRRGWVTYDRTVNIKEICWNLNNIRLHDCDIGAIVNRELTQRIRPVMVLANHKPVMRHDIKIASRLVAKFDKRHNLWQREDGKDTTNPMSSNNPLLANITEYLVDEGSYXXXXXXXXXXXXXXXXTVTGSDPSNIKVEVDDKLAAVLDRLILYLRFVHSFDYYSTTEYQIEDEMPHRCGILHARGAHIHVDKPLTQKEVEEYIKSFEMKAELILNSVELLTIDEAKKLGYKTLDESVDVFIAENTQEISKDKWLCPLSGKKFKGPDFVQKHILNKHMDKVELVKQNTEFFNNYLLD-PKRPQLPEHPSNRPGVKTT 2182
PR LHKT SIF+RN+ PN+ ++EI AL K Y GF+R+AL +P P+R+F R+ +VT+DR+VNIKEICW++ NIRL +C++ VNR+LT R+R + + H+P++R+DIK+A+RL+ D+R LW+ E G +S+ NP+L NIT+YL+DE + EEE LL + T +P+ I VE D+KL VLD+L+ YLR VHS DYY+T EY EDEMP RCG++H RG + ++ ++ EV E+ K+FE K + E L+ +EA K+G K ++ V+ F+ NTQE+ K+KWLCPLSGKKFKGP+FV+KHI NKH +K+E VK+ F L D +RP LPE RP V T
Sbjct: 408 PRPLHKTCSIFMRNIPPNISKAEITALCKRYPGFMRVALSEPQPERRFLRKAYVTFDRSVNIKEICWSVQNIRLRECELSPGVNRDLTYRVRNINGITMHRPIVRNDIKLAARLIHALDERALLWEGEQGDQM---VSAQNPILKNITDYLIDEVNAEEEELLFSAGRTPETETPKEGNPTEISVERDEKLIKVLDKLLFYLRIVHSVDYYNTCEYPNEDEMPTRCGMMHVRGP-LPPNR-VSHGEVAEWQKTFEEKLSPLFAVRETLSEEEAVKMGKKDPEQEVEKFVTANTQELGKEKWLCPLSGKKFKGPEFVRKHIFNKHGEKIEEVKKEVAF--QTLPDRQQRPALPEVEPLRPPVGTA 764 HSP 2 Score: 105.531 bits (262), Expect = 1.575e-22 Identity = 48/123 (39.02%), Postives = 79/123 (64.23%), Query Frame = 2
Query: 518 PPMLLFKHFLQQQDDDIEMDQAMKKYNEYKDSFVTKQLKAFFDSHSNQEWFREKYSPQFVEKRKVELEKNIQLRKEIFTYLHERNWMDNIKIHVDENDSIVRLMDAVVILLEGGNAHDLTILD 886
P M FK FL +D ++ +A+K+YN+YK F +Q++ FF +H ++EWFR KY P V K K E + ++ R F YL E +W++ +++ + ++ +I++++DA VI +EGG DL ILD
Sbjct: 147 PIMKTFKEFLLSLEDSVDETEAVKRYNDYKIDFRRQQMQEFFLAHKDEEWFRSKYHPDEVGKHKQESQAALRNRLSAFMYLMENSWLNEVQLDIAQSTAIIKVLDAAVIKMEGGTEIDLKILD 269
BLAST of serrate RNA effector molecule vs. Ensembl Xenopus
Match: SRRT (serrate, RNA effector molecule [Source:HGNC Symbol;Acc:HGNC:24101]) HSP 1 Score: 342.813 bits (878), Expect = 1.314e-103 Identity = 178/364 (48.90%), Postives = 248/364 (68.13%), Query Frame = 2
Query: 1094 PRALHKTFSIFLRNLHPNVLRSEIEALVKPYSGFLRLALQDPTPDRKFFRRGWVTYDRTVNIKEICWNLNNIRLHDCDIGAIVNRELTQRIRPVMVLANHKPVMRHDIKIASRLVAKFDKRHNLWQREDGKDTTNPMSSNNPLLANITEYLVDEGSYXXXXXXXXXXXXXXXXTVTGSDPSNIKVEVDDKLAAVLDRLILYLRFVHSFDYYSTTEYQIEDEMPHRCGILHARGAHIHVDKPLTQKEVEEYIKSFEMKAELILNSVELLTIDEAKKLGYKTLDESVDVFIAENTQEISKDKWLCPLSGKKFKGPDFVQKHILNKHMDKVELVKQNTEFFNNYLLD-PKRPQLPEHPSNRPGVKTT 2182
PR LHKT SIF+RN+ PN+ ++EI AL K Y GF+R+AL +P P+R+F R+ +VT+DR+VNIKEICW++ NIRL +C++ VNR+LT R+R + + H+P++R+DIK+A+RL+ D+R LW+ E G +S+ NP+L NIT+YL+DE + EEE LL + T +P+ I VE D+KL VLD+L+ YLR VHS DYY+T EY EDEMP RCG++H RG + ++ ++ EV E+ K+FE K + E L+ +EA K+G K ++ V+ F+ NTQE+ K+KWLCPLSGKKFKGP+FV+KHI NKH +K+E VK+ F L D +RP LPE RP V T
Sbjct: 403 PRPLHKTCSIFMRNIPPNISKAEITALCKRYPGFMRVALSEPQPERRFLRKAYVTFDRSVNIKEICWSVQNIRLRECELSPGVNRDLTYRVRNINGITMHRPIVRNDIKLAARLIHALDERALLWEGEQGDQM---VSAQNPILKNITDYLIDEVNAEEEELLFSAGRTPETETPKEGNPTEISVERDEKLIKVLDKLLFYLRIVHSVDYYNTCEYPNEDEMPTRCGMMHVRGP-LPPNR-VSHGEVAEWQKTFEEKLSPLFAVRETLSEEEAVKMGKKDPEQEVEKFVTANTQELGKEKWLCPLSGKKFKGPEFVRKHIFNKHGEKIEEVKKEVAF--QTLPDRQQRPALPEVEPLRPPVGTA 759 HSP 2 Score: 105.531 bits (262), Expect = 1.691e-22 Identity = 48/123 (39.02%), Postives = 79/123 (64.23%), Query Frame = 2
Query: 518 PPMLLFKHFLQQQDDDIEMDQAMKKYNEYKDSFVTKQLKAFFDSHSNQEWFREKYSPQFVEKRKVELEKNIQLRKEIFTYLHERNWMDNIKIHVDENDSIVRLMDAVVILLEGGNAHDLTILD 886
P M FK FL +D ++ +A+K+YN+YK F +Q++ FF +H ++EWFR KY P V K K E + ++ R F YL E +W++ +++ + ++ +I++++DA VI +EGG DL ILD
Sbjct: 147 PIMKTFKEFLLSLEDSVDETEAVKRYNDYKIDFRRQQMQEFFLAHKDEEWFRSKYHPDEVGKHKQESQAALRNRLSAFMYLMENSWLNEVQLDIAQSTAIIKVLDAAVIKMEGGTEIDLKILD 269
BLAST of serrate RNA effector molecule vs. Ensembl Xenopus
Match: SRRT (serrate, RNA effector molecule [Source:HGNC Symbol;Acc:HGNC:24101]) HSP 1 Score: 341.658 bits (875), Expect = 2.104e-103 Identity = 178/364 (48.90%), Postives = 248/364 (68.13%), Query Frame = 2
Query: 1094 PRALHKTFSIFLRNLHPNVLRSEIEALVKPYSGFLRLALQDPTPDRKFFRRGWVTYDRTVNIKEICWNLNNIRLHDCDIGAIVNRELTQRIRPVMVLANHKPVMRHDIKIASRLVAKFDKRHNLWQREDGKDTTNPMSSNNPLLANITEYLVDEGSYXXXXXXXXXXXXXXXXTVTGSDPSNIKVEVDDKLAAVLDRLILYLRFVHSFDYYSTTEYQIEDEMPHRCGILHARGAHIHVDKPLTQKEVEEYIKSFEMKAELILNSVELLTIDEAKKLGYKTLDESVDVFIAENTQEISKDKWLCPLSGKKFKGPDFVQKHILNKHMDKVELVKQNTEFFNNYLLD-PKRPQLPEHPSNRPGVKTT 2182
PR LHKT SIF+RN+ PN+ ++EI AL K Y GF+R+AL +P P+R+F R+ +VT+DR+VNIKEICW++ NIRL +C++ VNR+LT R+R + + H+P++R+DIK+A+RL+ D+R LW+ E G +S+ NP+L NIT+YL+DE + EEE LL + T +P+ I VE D+KL VLD+L+ YLR VHS DYY+T EY EDEMP RCG++H RG + ++ ++ EV E+ K+FE K + E L+ +EA K+G K ++ V+ F+ NTQE+ K+KWLCPLSGKKFKGP+FV+KHI NKH +K+E VK+ F L D +RP LPE RP V T
Sbjct: 372 PRPLHKTCSIFMRNIPPNISKAEITALCKRYPGFMRVALSEPQPERRFLRKAYVTFDRSVNIKEICWSVQNIRLRECELSPGVNRDLTYRVRNINGITMHRPIVRNDIKLAARLIHALDERALLWEGEQGDQM---VSAQNPILKNITDYLIDEVNAEEEELLFSAGRTPETETPKEGNPTEISVERDEKLIKVLDKLLFYLRIVHSVDYYNTCEYPNEDEMPTRCGMMHVRGP-LPPNR-VSHGEVAEWQKTFEEKLSPLFAVRETLSEEEAVKMGKKDPEQEVEKFVTANTQELGKEKWLCPLSGKKFKGPEFVRKHIFNKHGEKIEEVKKEVAF--QTLPDRQQRPALPEVEPLRPPVGTA 728 HSP 2 Score: 105.145 bits (261), Expect = 1.907e-22 Identity = 48/123 (39.02%), Postives = 79/123 (64.23%), Query Frame = 2
Query: 518 PPMLLFKHFLQQQDDDIEMDQAMKKYNEYKDSFVTKQLKAFFDSHSNQEWFREKYSPQFVEKRKVELEKNIQLRKEIFTYLHERNWMDNIKIHVDENDSIVRLMDAVVILLEGGNAHDLTILD 886
P M FK FL +D ++ +A+K+YN+YK F +Q++ FF +H ++EWFR KY P V K K E + ++ R F YL E +W++ +++ + ++ +I++++DA VI +EGG DL ILD
Sbjct: 147 PIMKTFKEFLLSLEDSVDETEAVKRYNDYKIDFRRQQMQEFFLAHKDEEWFRSKYHPDEVGKHKQESQAALRNRLSAFMYLMENSWLNEVQLDIAQSTAIIKVLDAAVIKMEGGTEIDLKILD 269
BLAST of serrate RNA effector molecule vs. Ensembl Xenopus
Match: SRRT (serrate, RNA effector molecule [Source:HGNC Symbol;Acc:HGNC:24101]) HSP 1 Score: 339.732 bits (870), Expect = 4.502e-103 Identity = 178/365 (48.77%), Postives = 244/365 (66.85%), Query Frame = 2
Query: 1094 PRALHKTFSIFLRNLHPNVLRSEIEALVKPYSGFLRLALQDPTPDRKFFRRGWVTYDRTVNIKEICWNLNNIRLHDCDIGAIVNRELTQRIRPVMVLANHKPVMRHDIKIASRLVAKFDKRHNLWQREDGKDTTNPMSSNNPLLANITEYLVDEGSYXXXXXXXXXXXXXXXXTVTGSDPSNIKVEVDDKLAAVLDRLILYLRFVHSFDYYSTTEYQIEDEMPHRCGILHARGAHIHVDKPL-----TQKEVEEYIKSFEMKAELILNSVELLTIDEAKKLGYKTLDESVDVFIAENTQEISKDKWLCPLSGKKFKGPDFVQKHILNKHMDKVELVKQNTEFFNNYLLD-PKRPQLPEHPSNRPG 2170
PR LHKT SIF+RN+ PN+ ++EI AL K Y GF+R+AL +P P+R+F R+ +VT+DR+VNIKEICW++ NIRL +C++ VNR+LT R+R + + H+P++R+DIK+A+RL+ D+R LW+ E G +S+ NP+L NIT+YL+DE + EEE LL + T +P+ I VE D+KL VLD+L+ YLR VHS DYY+T EY EDEMP RCG++H RG PL + EV E+ K+FE K + E L+ +EA K+G K ++ V+ F+ NTQE+ K+KWLCPLSGKKFKGP+FV+KHI NKH +K+E VK+ F L D +RP LPE PG
Sbjct: 392 PRPLHKTCSIFMRNIPPNISKAEITALCKRYPGFMRVALSEPQPERRFLRKAYVTFDRSVNIKEICWSVQNIRLRECELSPGVNRDLTYRVRNINGITMHRPIVRNDIKLAARLIHALDERALLWEGEQGDQM---VSAQNPILKNITDYLIDEVNAEEEELLFSAGRTPETETPKEGNPTEISVERDEKLIKVLDKLLFYLRIVHSVDYYNTCEYPNEDEMPTRCGMMHVRG-------PLPPNRVSHGEVAEWQKTFEEKLSPLFAVRETLSEEEAVKMGKKDPEQEVEKFVTANTQELGKEKWLCPLSGKKFKGPEFVRKHIFNKHGEKIEEVKKEVAF--QTLPDRQQRPALPEVKPLYPG 744 HSP 2 Score: 105.145 bits (261), Expect = 1.639e-22 Identity = 48/123 (39.02%), Postives = 79/123 (64.23%), Query Frame = 2
Query: 518 PPMLLFKHFLQQQDDDIEMDQAMKKYNEYKDSFVTKQLKAFFDSHSNQEWFREKYSPQFVEKRKVELEKNIQLRKEIFTYLHERNWMDNIKIHVDENDSIVRLMDAVVILLEGGNAHDLTILD 886
P M FK FL +D ++ +A+K+YN+YK F +Q++ FF +H ++EWFR KY P V K K E + ++ R F YL E +W++ +++ + ++ +I++++DA VI +EGG DL ILD
Sbjct: 147 PIMKTFKEFLLSLEDSVDETEAVKRYNDYKIDFRRQQMQEFFLAHKDEEWFRSKYHPDEVGKHKQESQAALRNRLSAFMYLMENSWLNEVQLDIAQSTAIIKVLDAAVIKMEGGTEIDLKILD 269
BLAST of serrate RNA effector molecule vs. Ensembl Mouse
Match: Srrt (serrate RNA effector molecule homolog (Arabidopsis) [Source:MGI Symbol;Acc:MGI:1933527]) HSP 1 Score: 365.925 bits (938), Expect = 3.827e-112 Identity = 190/362 (52.49%), Postives = 255/362 (70.44%), Query Frame = 2
Query: 1091 EPRALHKTFSIFLRNLHPNVLRSEIEALVKPYSGFLRLALQDPTPDRKFFRRGWVTYDRTVNIKEICWNLNNIRLHDCDIGAIVNRELTQRIRPVMVLANHKPVMRHDIKIASRLVAKFDKRHNLWQREDGK-DTTNPMSSNNPLLANITEYLVDEGSYXXXXXXXXXXXXXXXXTVTGSDPSNIKVEVDDKLAAVLDRLILYLRFVHSFDYYSTTEYQIEDEMPHRCGILHARGAHIHVDKPLTQKEVEEYIKSFEMKAELILNSVELLTIDEAKKLGYKTLDESVDVFIAENTQEISKDKWLCPLSGKKFKGPDFVQKHILNKHMDKVELVKQNTEFFNNYLLDPKRPQLPE-HPSNRPG 2170
+PR LHKT S+F+RN+ PN+ R+EI +L K Y GF+R+AL +P P+R+FFRRGWVT+DR+VNIKEICWNL NIRL +C++ VNR+LT+R+R + + HK ++R+DIK+A++L+ D R LW E G + S NP+L NIT+YL++E S EEE LLG + E +P+ I VE D+KL VLD+L+LYLR VHS DYY+T EY EDEMP+RCGI+H RG ++ EV E+ K+FE K +L+ E L+ +EA+K+G K ++ V+ F+ NTQE+ KDKWLCPLSGKKFKGP+FV+KHI NKH +K+E VK+ FFNN+L D KRP LPE P+ PG
Sbjct: 412 KPRPLHKTCSLFMRNIAPNISRAEIISLCKRYPGFMRVALSEPQPERRFFRRGWVTFDRSVNIKEICWNLQNIRLRECELSPGVNRDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWASEPGTPPVPTSLPSQNPILKNITDYLIEEVSAEEEELLGSSGGPPPEEPPKEGNPAEINVERDEKLIKVLDKLLLYLRIVHSLDYYNTCEYPNEDEMPNRCGIIHVRGP--MPPNRISHGEVLEWQKTFEEKLTPLLSVRESLSEEEAQKMGRKDPEQEVEKFVTSNTQELGKDKWLCPLSGKKFKGPEFVRKHIFNKHAEKIEEVKKEVAFFNNFLTDAKRPALPEIKPAQPPG 771 HSP 2 Score: 112.464 bits (280), Expect = 7.633e-25 Identity = 53/122 (43.44%), Postives = 79/122 (64.75%), Query Frame = 2
Query: 518 PPMLLFKHFLQQQDDDIEMDQAMKKYNEYKDSFVTKQLKAFFDSHSNQEWFREKYSPQFVEKRKVELEKNIQLRKEIFTYLHERNWMDNIKIHVDENDSIVRLMDAVVILLEGGNAHDLTIL 883
P M FK FL DD ++ +A+K+YN+YK F +Q++ FF +H ++EWFR KY P V KR+ E +Q R ++F L E W DN+ + +D+ D+IV+++DA VI +EGG +DL IL
Sbjct: 147 PIMKSFKEFLLSLDDSVDETEAVKRYNDYKLDFRRQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLKVFLSLMESGWFDNLLLDIDKADAIVKMLDAAVIKMEGGTENDLRIL 268
BLAST of serrate RNA effector molecule vs. Ensembl Mouse
Match: Srrt (serrate RNA effector molecule homolog (Arabidopsis) [Source:MGI Symbol;Acc:MGI:1933527]) HSP 1 Score: 365.925 bits (938), Expect = 4.333e-112 Identity = 190/362 (52.49%), Postives = 255/362 (70.44%), Query Frame = 2
Query: 1091 EPRALHKTFSIFLRNLHPNVLRSEIEALVKPYSGFLRLALQDPTPDRKFFRRGWVTYDRTVNIKEICWNLNNIRLHDCDIGAIVNRELTQRIRPVMVLANHKPVMRHDIKIASRLVAKFDKRHNLWQREDGK-DTTNPMSSNNPLLANITEYLVDEGSYXXXXXXXXXXXXXXXXTVTGSDPSNIKVEVDDKLAAVLDRLILYLRFVHSFDYYSTTEYQIEDEMPHRCGILHARGAHIHVDKPLTQKEVEEYIKSFEMKAELILNSVELLTIDEAKKLGYKTLDESVDVFIAENTQEISKDKWLCPLSGKKFKGPDFVQKHILNKHMDKVELVKQNTEFFNNYLLDPKRPQLPE-HPSNRPG 2170
+PR LHKT S+F+RN+ PN+ R+EI +L K Y GF+R+AL +P P+R+FFRRGWVT+DR+VNIKEICWNL NIRL +C++ VNR+LT+R+R + + HK ++R+DIK+A++L+ D R LW E G + S NP+L NIT+YL++E S EEE LLG + E +P+ I VE D+KL VLD+L+LYLR VHS DYY+T EY EDEMP+RCGI+H RG ++ EV E+ K+FE K +L+ E L+ +EA+K+G K ++ V+ F+ NTQE+ KDKWLCPLSGKKFKGP+FV+KHI NKH +K+E VK+ FFNN+L D KRP LPE P+ PG
Sbjct: 412 KPRPLHKTCSLFMRNIAPNISRAEIISLCKRYPGFMRVALSEPQPERRFFRRGWVTFDRSVNIKEICWNLQNIRLRECELSPGVNRDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWASEPGTPPVPTSLPSQNPILKNITDYLIEEVSAEEEELLGSSGGPPPEEPPKEGNPAEINVERDEKLIKVLDKLLLYLRIVHSLDYYNTCEYPNEDEMPNRCGIIHVRGP--MPPNRISHGEVLEWQKTFEEKLTPLLSVRESLSEEEAQKMGRKDPEQEVEKFVTSNTQELGKDKWLCPLSGKKFKGPEFVRKHIFNKHAEKIEEVKKEVAFFNNFLTDAKRPALPEIKPAQPPG 771 HSP 2 Score: 112.849 bits (281), Expect = 7.050e-25 Identity = 53/122 (43.44%), Postives = 79/122 (64.75%), Query Frame = 2
Query: 518 PPMLLFKHFLQQQDDDIEMDQAMKKYNEYKDSFVTKQLKAFFDSHSNQEWFREKYSPQFVEKRKVELEKNIQLRKEIFTYLHERNWMDNIKIHVDENDSIVRLMDAVVILLEGGNAHDLTIL 883
P M FK FL DD ++ +A+K+YN+YK F +Q++ FF +H ++EWFR KY P V KR+ E +Q R ++F L E W DN+ + +D+ D+IV+++DA VI +EGG +DL IL
Sbjct: 147 PIMKSFKEFLLSLDDSVDETEAVKRYNDYKLDFRRQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLKVFLSLMESGWFDNLLLDIDKADAIVKMLDAAVIKMEGGTENDLRIL 268
BLAST of serrate RNA effector molecule vs. Ensembl Mouse
Match: Srrt (serrate RNA effector molecule homolog (Arabidopsis) [Source:MGI Symbol;Acc:MGI:1933527]) HSP 1 Score: 365.925 bits (938), Expect = 4.460e-112 Identity = 190/362 (52.49%), Postives = 255/362 (70.44%), Query Frame = 2
Query: 1091 EPRALHKTFSIFLRNLHPNVLRSEIEALVKPYSGFLRLALQDPTPDRKFFRRGWVTYDRTVNIKEICWNLNNIRLHDCDIGAIVNRELTQRIRPVMVLANHKPVMRHDIKIASRLVAKFDKRHNLWQREDGK-DTTNPMSSNNPLLANITEYLVDEGSYXXXXXXXXXXXXXXXXTVTGSDPSNIKVEVDDKLAAVLDRLILYLRFVHSFDYYSTTEYQIEDEMPHRCGILHARGAHIHVDKPLTQKEVEEYIKSFEMKAELILNSVELLTIDEAKKLGYKTLDESVDVFIAENTQEISKDKWLCPLSGKKFKGPDFVQKHILNKHMDKVELVKQNTEFFNNYLLDPKRPQLPE-HPSNRPG 2170
+PR LHKT S+F+RN+ PN+ R+EI +L K Y GF+R+AL +P P+R+FFRRGWVT+DR+VNIKEICWNL NIRL +C++ VNR+LT+R+R + + HK ++R+DIK+A++L+ D R LW E G + S NP+L NIT+YL++E S EEE LLG + E +P+ I VE D+KL VLD+L+LYLR VHS DYY+T EY EDEMP+RCGI+H RG ++ EV E+ K+FE K +L+ E L+ +EA+K+G K ++ V+ F+ NTQE+ KDKWLCPLSGKKFKGP+FV+KHI NKH +K+E VK+ FFNN+L D KRP LPE P+ PG
Sbjct: 412 KPRPLHKTCSLFMRNIAPNISRAEIISLCKRYPGFMRVALSEPQPERRFFRRGWVTFDRSVNIKEICWNLQNIRLRECELSPGVNRDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWASEPGTPPVPTSLPSQNPILKNITDYLIEEVSAEEEELLGSSGGPPPEEPPKEGNPAEINVERDEKLIKVLDKLLLYLRIVHSLDYYNTCEYPNEDEMPNRCGIIHVRGP--MPPNRISHGEVLEWQKTFEEKLTPLLSVRESLSEEEAQKMGRKDPEQEVEKFVTSNTQELGKDKWLCPLSGKKFKGPEFVRKHIFNKHAEKIEEVKKEVAFFNNFLTDAKRPALPEIKPAQPPG 771 HSP 2 Score: 112.464 bits (280), Expect = 7.352e-25 Identity = 53/122 (43.44%), Postives = 79/122 (64.75%), Query Frame = 2
Query: 518 PPMLLFKHFLQQQDDDIEMDQAMKKYNEYKDSFVTKQLKAFFDSHSNQEWFREKYSPQFVEKRKVELEKNIQLRKEIFTYLHERNWMDNIKIHVDENDSIVRLMDAVVILLEGGNAHDLTIL 883
P M FK FL DD ++ +A+K+YN+YK F +Q++ FF +H ++EWFR KY P V KR+ E +Q R ++F L E W DN+ + +D+ D+IV+++DA VI +EGG +DL IL
Sbjct: 147 PIMKSFKEFLLSLDDSVDETEAVKRYNDYKLDFRRQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLKVFLSLMESGWFDNLLLDIDKADAIVKMLDAAVIKMEGGTENDLRIL 268
BLAST of serrate RNA effector molecule vs. Ensembl Mouse
Match: Srrt (serrate RNA effector molecule homolog (Arabidopsis) [Source:MGI Symbol;Acc:MGI:1933527]) HSP 1 Score: 332.413 bits (851), Expect = 1.944e-103 Identity = 183/364 (50.27%), Postives = 247/364 (67.86%), Query Frame = 2
Query: 1091 EPRALHKTFSIFLRNLHPNVLRSEIEALVKPYSGFLRLALQDPTPDR--KFFRRGWVTYDRTVNIKEICWNLNNIRLHDCDIGAIVNRELTQRIRPVMVLANHKPVMRHDIKIASRLVAKFDKRHNLWQREDG-KDTTNPMSSNNPLLANITEYLVDEGSYXXXXXXXXXXXXXXXXTVTGSDPSNIKVEVDDKLAAVLDRLILYLRFVHSFDYYSTTEYQIEDEMPHRCGILHARGAHIHVDKPLTQKEVEEYIKSFEMKAELILNSVELLTIDEAKKLGYKTLDESVDVFIAENTQEISKDKWLCPLSGKKFKGPDFVQKHILNKHMDKVELVKQNTEFFNNYLLDPKRPQLPE-HPSNRPG 2170
+PR LHKT S+F+RN+ PN+ R+EI ++ SG + L + R +FFRRGWVT+DR+VNIKEICWNL NIRL +C++ VNR+LT+R+R + + HK ++R+DIK+A++L+ D R LW E G + S NP+L NIT+YL++E S EEE LLG + E +P+ I VE D+KL VLD+L+LYLR VHS DYY+T EY EDEMP+RCGI+H RG ++ EV E+ K+FE K +L+ E L+ +EA+K+G K ++ V+ F+ NTQE+ KDKWLCPLSGKKFKGP+FV+KHI NKH +K+E VK+ FFNN+L D KRP LPE P+ PG
Sbjct: 56 KPRPLHKTCSLFMRNIAPNISRAEIISV----SGDIGLRGRVGVNPRSFRFFRRGWVTFDRSVNIKEICWNLQNIRLRECELSPGVNRDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWASEPGTPPVPTSLPSQNPILKNITDYLIEEVSAEEEELLGSSGGPPPEEPPKEGNPAEINVERDEKLIKVLDKLLLYLRIVHSLDYYNTCEYPNEDEMPNRCGIIHVRGPM--PPNRISHGEVLEWQKTFEEKLTPLLSVRESLSEEEAQKMGRKDPEQEVEKFVTSNTQELGKDKWLCPLSGKKFKGPEFVRKHIFNKHAEKIEEVKKEVAFFNNFLTDAKRPALPEIKPAQPPG 413
BLAST of serrate RNA effector molecule vs. Ensembl Mouse
Match: Srrt (serrate RNA effector molecule homolog (Arabidopsis) [Source:MGI Symbol;Acc:MGI:1933527]) HSP 1 Score: 199.134 bits (505), Expect = 2.686e-57 Identity = 99/180 (55.00%), Postives = 131/180 (72.78%), Query Frame = 2
Query: 1634 SNIKVEVDDKLAAVLDRLILYLRFVHSFDYYSTTEYQIEDEMPHRCGILHARGAHIHVDKPLTQKEVEEYIKSFEMKAELILNSVELLTIDEAKKLGYKTLDESVDVFIAENTQEISKDKWLCPLSGKKFKGPDFVQKHILNKHMDKVELVKQNTEFFNNYLLDPKRPQLPE-HPSNRPG 2170
+ I VE D+KL VLD+L+LYLR VHS DYY+T EY EDEMP+RCGI+H RG + ++ ++ EV E+ K+FE K +L+ E L+ +EA+K+G K ++ V+ F+ NTQE+ KDKWLCPLSGKKFKGP+FV+KHI NKH +K+E VK+ FFNN+L D KRP LPE P+ PG
Sbjct: 17 AEINVERDEKLIKVLDKLLLYLRIVHSLDYYNTCEYPNEDEMPNRCGIIHVRGP-MPPNR-ISHGEVLEWQKTFEEKLTPLLSVRESLSEEEAQKMGRKDPEQEVEKFVTSNTQELGKDKWLCPLSGKKFKGPEFVRKHIFNKHAEKIEEVKKEVAFFNNFLTDAKRPALPEIKPAQPPG 194
BLAST of serrate RNA effector molecule vs. UniProt/SwissProt
Match: sp|B4NYV0|SRRT_DROYA (Serrate RNA effector molecule homolog OS=Drosophila yakuba OX=7245 GN=Ars2 PE=3 SV=1) HSP 1 Score: 380.563 bits (976), Expect = 4.186e-116 Identity = 189/377 (50.13%), Postives = 256/377 (67.90%), Query Frame = 2
Query: 1091 EPRALHKTFSIFLRNLHPNVLRSEIEALVKPYSGFLRLALQDPTPDRKFFRRGWVTYDRTVNIKEICWNLNNIRLHDCDIGAIVNRELTQRIRPVMVLANHKPVMRHDIKIASRLVAKFDKRHNLWQR---------------EDGKDTTNPMSSNNPLLANITEYLVDEGSYXXXXXXXXXXXXXXXXTVTGSDPSNIKVEVDDKLAAVLDRLILYLRFVHSFDYYSTTEYQIEDEMPHRCGILHARG-AHIHVDKPLTQKEVEEYIKSFEMKAELILNSVELLTIDEAKKLGYKTLDESVDVFIAENTQEISKDKWLCPLSGKKFKGPDFVQKHILNKHMDKVELVKQNTEFFNNYLLDPKRPQLPEHP--SNRP 2167
+PRALH+T SIFLRNL P++ R+EIEA+ ++G+LR+A+ DP +R+++RRGW+T+ R VNIKEICW LNN RL DC++GAIVNR+L++R+RP L HK V+R DIK+ +++ D+R LW E+G +T +S NP+L NIT+YL++E S + L LT D +E D++L +VLDRL+LYLR VHS DYY+ EY EDEMP+RCGI+HARG A + V T +V+EYIK++E K + L LL+ +E K LG K + V+ F+ NTQE++KDKWLCPLSGKKFKGP+F++KHI NKH +KV+ V++ ++FNNYL DPKRPQLPEHP S RP
Sbjct: 508 QPRALHRTSSIFLRNLAPSITRAEIEAVCNRFTGYLRVAIADPLVERRWYRRGWITFMRDVNIKEICWGLNNQRLRDCEMGAIVNRDLSRRVRPANGLTAHKQVVRSDIKLCAKIALNLDERFRLWAEVPTDDSNSARADESSENGSGSTYGFNSKNPVLQNITDYLIEEAS--------AEEDELLGLTGENKDTEGEAIERDEQLISVLDRLVLYLRIVHSVDYYNHCEYPYEDEMPNRCGIIHARGPAPVRV----TNNDVQEYIKTYESKLQQFLTKTVLLSDEEIKDLGAKDAETEVEKFVQANTQELAKDKWLCPLSGKKFKGPEFIRKHIFNKHDEKVDEVRKEVQYFNNYLRDPKRPQLPEHPGTSKRP 872 HSP 2 Score: 110.153 bits (274), Expect = 3.438e-23 Identity = 61/172 (35.47%), Postives = 91/172 (52.91%), Query Frame = 2
Query: 512 TQPPMLLFKHFLQQQDDDIEMDQAMKKYNEYKDSFVTKQLKAFFDSHSNQEWFREKYSPQFVEKRKVELEKNIQLRKEIFTYLHERNWMDNIKIHVDENDSIVRLMDAVVILLEGGNAHDLTILDSKRYRSESPNDSHILEDVVVKSPEKVTSSEGIEVVNKEIIEPDDKKF 1027
TQP ML K FL QD++I + M+KY EYK F +QL FF +H ++EWF+ KY P+ KR E +Q R ++F L E + ++K+ + D+++R++D VI LEGG DL +LD E P D + E K E ++ + K I P ++K
Sbjct: 152 TQPAMLNLKQFLDTQDENISDSEVMRKYTEYKTDFKRQQLNEFFVAHKDEEWFKNKYHPEDSVKRSEEQRGFLQRRTDVFVELLENGTIGSVKVDSSQGDALIRVLDTCVIKLEGGTDEDLKVLD------EKPKDLVVYE-------RKTEPMESVKAMEKAISSPKEEKI 310
BLAST of serrate RNA effector molecule vs. UniProt/SwissProt
Match: sp|Q17FR9|SRRT_AEDAE (Serrate RNA effector molecule homolog OS=Aedes aegypti OX=7159 GN=Ars2 PE=3 SV=1) HSP 1 Score: 379.022 bits (972), Expect = 1.357e-115 Identity = 189/362 (52.21%), Postives = 250/362 (69.06%), Query Frame = 2
Query: 1094 PRALHKTFSIFLRNLHPNVLRSEIEALVKPYSGFLRLALQDPTPDRKFFRRGWVTYDRTVNIKEICWNLNNIRLHDCDIGAIVNRELTQRIRPVMVLANHKPVMRHDIKIASRLVAKFDKRHNLWQREDGKDTTN----PMSSNNPLLANITEYLVDEGSYXXXXXXXXXXXXXXXXTVTGSDPSNIK--VEVDDKLAAVLDRLILYLRFVHSFDYYSTTEYQIEDEMPHRCGILHARGAHIHVDKPLTQKEVEEYIKSFEMKAELILNSVELLTIDEAKKLGYKTLDESVDVFIAENTQEISKDKWLCPLSGKKFKGPDFVQKHILNKHMDKVELVKQNTEFFNNYLLDPKRPQLPEHPSN 2161
PRALH+T SIFLRNL P++ ++E+EA+ K Y+GFLR+A+ DP +R++FRRGWVT+ R VNIKEICWNLNNIRL DC++GAIVN++L++R+RPV L HK ++R DIK+ +++ D + LW+ ++ N + S NP+L NIT+YL++E S + L L+ + SN VE D +L VLD+LILYLR VHS D+Y+ EY EDEMP+RCGI+HARG +T E++EYI++FE K L L +E KKLG K + V+ FI NTQE++KDKWLCPLSGKKFKGPDFV+KHI NKH +KV+ V++ E+FNNYL D KRPQLPEHP N
Sbjct: 508 PRALHRTSSIFLRNLAPSITKAEVEAMCKRYNGFLRVAIADPLLERRWFRRGWVTFRRDVNIKEICWNLNNIRLRDCELGAIVNKDLSRRVRPVNGLTCHKTIVRSDIKLCAKIAHNLDDKVGLWKEQEDNGEKNGESFGLQSKNPVLQNITDYLIEEAS--------AEEDELLGLSTEAAKKSNDGELVERDTQLIEVLDKLILYLRVVHSIDFYNHCEYPYEDEMPNRCGIIHARGPPPQ--NKVTSNEIQEYIRTFEGKMGSFLARAVDLEEEEMKKLGAKDAEAEVEKFIQANTQELAKDKWLCPLSGKKFKGPDFVRKHIFNKHNEKVDEVRKEVEYFNNYLKDTKRPQLPEHPGN 859 HSP 2 Score: 103.605 bits (257), Expect = 3.528e-21 Identity = 52/127 (40.94%), Postives = 75/127 (59.06%), Query Frame = 2
Query: 512 TQPPMLLFKHFLQQQDDDIEMDQAMKKYNEYKDSFVTKQLKAFFDSHSNQEWFREKYSPQFVEKRKVELEKNIQLRKEIFTYLHERNWMDNIKIHVDENDSIVRLMDAVVILLEGGNAHDLTILDSK 892
TQP M+ K FL QDD I +A++KYN+YK F +QL FF +H ++EWF+ KY P+ KRK E ++ R ++F L + + + + D ++RL+D VVI LEGG DL +LD K
Sbjct: 133 TQPCMMTLKQFLATQDDSISDSEAIQKYNDYKLEFKRQQLNEFFVAHKDEEWFKMKYHPEESLKRKEEQFGFLKRRCDVFVELLDHGDISKVSVDTSNTDPLLRLLDTVVIKLEGGTDEDLKVLDEK 259
BLAST of serrate RNA effector molecule vs. UniProt/SwissProt
Match: sp|Q28WQ8|SRRT_DROPS (Serrate RNA effector molecule homolog OS=Drosophila pseudoobscura pseudoobscura OX=46245 GN=Ars2 PE=3 SV=2) HSP 1 Score: 373.244 bits (957), Expect = 2.656e-113 Identity = 186/392 (47.45%), Postives = 255/392 (65.05%), Query Frame = 2
Query: 1094 PRALHKTFSIFLRNLHPNVLRSEIEALVKPYSGFLRLALQDPTPDRKFFRRGWVTYDRTVNIKEICWNLNNIRLHDCDIGAIVNRELTQRIRPVMVLANHKPVMRHDIKIASRLVAKFDKRHNLWQR----------------EDGKDTTNPMSSNNPLLANITEYLVDEGSYXXXXXXXXXXXXXXXXTVTGS--DPSNIKVEVDDKLAAVLDRLILYLRFVHSFDYYSTTEYQIEDEMPHRCGILHARGAHIHVDKPLTQKEVEEYIKSFEMKAELILNSVELLTIDEAKKLGYKTLDESVDVFIAENTQEISKDKWLCPLSGKKFKGPDFVQKHILNKHMDKVELVKQNTEFFNNYLLDPKRPQLPEHPSNRPGVKTTESGEIRNEGQF 2215
PRA+H+T SIFLRNL P++ ++EIEAL +SG+LR A+ DP +R+++RRGW+T+ R VNIKEICW+LNN RL DC++GAIVNR+L++R+RP + HK V+R DIK+ +R+V D++ LW +G ++ +S NP+L NIT+YL+ + L ++G D +E D++L +VLDRL+LYLR VHS DYY+ EY EDEMP+RCGI+HARG +T E+ EYIKS+E K L LL+ D+ K LG K D V+ F+ NTQE++KDKWLCPLSGKKFKGP+F++KHI NKH +KV+ V++ ++FNNYL DPKRPQLPEHP + VK E+ +R G +
Sbjct: 516 PRAMHRTSSIFLRNLAPSITKAEIEALCSRFSGYLRTAIADPLVERRWYRRGWITFTRDVNIKEICWSLNNQRLRDCEMGAIVNRDLSRRVRPANGITAHKQVVRSDIKLCARIVMNLDEKFKLWSEGPLSKPSPASDSEATAANGSGSSYGFNSKNPVLQNITDYLI----------EEASAEEEELLGLSGDRKDGEGEPIERDEQLLSVLDRLVLYLRIVHSVDYYNHCEYPYEDEMPNRCGIIHARGP---APSRVTSNELNEYIKSYEGKLLQFLTKTALLSEDQIKDLGAKNADTEVEKFVQANTQELAKDKWLCPLSGKKFKGPEFIRKHIFNKHEEKVDEVRKEVQYFNNYLRDPKRPQLPEHPGS---VKRPETESVRGPGGY 891 HSP 2 Score: 104.76 bits (260), Expect = 1.502e-21 Identity = 50/127 (39.37%), Postives = 74/127 (58.27%), Query Frame = 2
Query: 512 TQPPMLLFKHFLQQQDDDIEMDQAMKKYNEYKDSFVTKQLKAFFDSHSNQEWFREKYSPQFVEKRKVELEKNIQLRKEIFTYLHERNWMDNIKIHVDENDSIVRLMDAVVILLEGGNAHDLTILDSK 892
TQP ML K FL QD++I + M+KY EYK F +QL FF +H ++EWF+ KY P+ R E ++ R ++F L E + ++K+ D+++R++D VI LEGG DL +LD K
Sbjct: 150 TQPAMLNLKQFLDTQDENISDSEVMRKYTEYKTDFKRQQLNEFFVAHKDEEWFKNKYHPEDSVNRSEEQRGFLRRRTDVFVELLENGTIGSVKVDSSHGDALIRVLDTCVIKLEGGTDEDLKVLDEK 276
BLAST of serrate RNA effector molecule vs. UniProt/SwissProt
Match: sp|B3N3F7|SRRT_DROER (Serrate RNA effector molecule homolog OS=Drosophila erecta OX=7220 GN=Ars2 PE=3 SV=1) HSP 1 Score: 372.474 bits (955), Expect = 5.304e-113 Identity = 208/468 (44.44%), Postives = 285/468 (60.90%), Query Frame = 2
Query: 848 LEGGNAHDLTILDSKRYRSESPNDSHILEDVVVKSPE-KVTSSEGIEVVNKEIIEPDDKKFXXXXXXXXXXXXKFEKKSELQEPRALHKTFSIFLRNLHPNVLRSEIEALVKPYSGFLRLALQDPTPDRKFFRRGWVTYDRTVNIKEICWNLNNIRLHDCDIGAIVNRELTQRIRPVMVLANHKPVMRHDIKIASRLVAKFDKRHNLWQR---------------EDGKDTTNPMSSNNPLLANITEYLVDEGSYXXXXXXXXXXXXXXXXTVTGSDPSNIKVEVDDKLAAVLDRLILYLRFVHSFDYYSTTEYQIEDEMPHRCGILHARG-AHIHVDKPLTQKEVEEYIKSFEMKAELILNSVELLTIDEAKKLGYKTLDESVDVFIAENTQEISKDKWLCPLSGKKFKGPDFVQKHILNKHMDKVELVKQNTEFFNNYLLDPKRPQLPEHPSNRPGVKTTESGEIR 2200
LEG + LDSK +E+ D +KSPE T +G + + +E D+KK + E K + +PRALH+T SIFLRNL P++ R+EIE + ++G+LR+A+ DP +R+++RRGW+T+ R VNIKEICW LNN RL DC++GAIVNR+L++R+RP + HK V+R DIK+ +++ D+R LW E+G +T +S NP+L NIT+YL+ L LT D +E D++L +VLDRL+LYLR VHS DYY+ EY EDEMP+RCGI+HARG A + V T +V+EYIK++E K + L LL+ +E K LG K + V+ F+ NTQE++KDKWLCPLSGKKFKGP+F++KHI NKH +KV+ V++ ++FNNYL DPKRPQLPEHP K TES R
Sbjct: 437 LEGKEIVEPKELDSKSNTAEN--------DDTLKSPEISPTPIKGTDNGDDNKVEEDEKKPSVDEIKVVETETIDLDKVKNGQPRALHRTSSIFLRNLAPSITRAEIETVCNRFTGYLRVAIADPLVERRWYRRGWITFMRDVNIKEICWGLNNHRLRDCEMGAIVNRDLSRRVRPANGITAHKQVVRSDIKLCAKIALNLDERFRLWAEVPTDDSHPSRADESTENGSGSTYGFNSKNPVLQNITDYLI--------EEASAEEEELLGLTGENKDTDGEPIERDEQLISVLDRLVLYLRIVHSVDYYNHCEYPYEDEMPNRCGIIHARGPAPVRV----TNNDVQEYIKTYESKLQQFLTKTVLLSDEEIKDLGAKDPETEVEKFVQANTQELAKDKWLCPLSGKKFKGPEFIRKHIFNKHEEKVDEVRKEVQYFNNYLRDPKRPQLPEHPGT---SKRTESESAR 881 HSP 2 Score: 110.538 bits (275), Expect = 2.509e-23 Identity = 60/162 (37.04%), Postives = 89/162 (54.94%), Query Frame = 2
Query: 512 TQPPMLLFKHFLQQQDDDIEMDQAMKKYNEYKDSFVTKQLKAFFDSHSNQEWFREKYSPQFVEKRKVELEKNIQLRKEIFTYLHERNWMDNIKIHVDENDSIVRLMDAVVILLEGGNAHDLTILDSKRY------RSESPNDSHILEDVVVKSPEKVTSSEG 979
TQP ML K FL QD++I + M+KY EYK F +QL FF +H ++EWF+ KY P+ KR E +Q R ++F L E + ++K+ + D+++R++D VI LEGG DL +LD K R P +S + + SP++ SEG
Sbjct: 151 TQPAMLNLKQFLDTQDENISDSEVMRKYTEYKTDFKRQQLNEFFVAHKDEEWFKNKYHPEDSVKRSDEQRGFLQRRTDVFVELLENGTIGSVKVDSSQGDALIRVLDTCVIKLEGGTDEDLKVLDEKPKDPVVCERKAEPIESAKAVEKTINSPKEEKISEG 312
BLAST of serrate RNA effector molecule vs. UniProt/SwissProt
Match: sp|B4LIK8|SRRT_DROVI (Serrate RNA effector molecule homolog OS=Drosophila virilis OX=7244 GN=Ars2 PE=3 SV=1) HSP 1 Score: 372.089 bits (954), Expect = 9.132e-113 Identity = 198/477 (41.51%), Postives = 279/477 (58.49%), Query Frame = 2
Query: 851 EGGNA-HDLTILDSKRYRSESPNDSHILEDVVVKSPEKVTSSEGIEVVNKEIIEPDDKKFXXXXXXXXXXXXKFEKKSELQEPRALHKTFSIFLRNLHPNVLRSEIEALVKPYSGFLRLALQDPTPDRKFFRRGWVTYDRTVNIKEICWNLNNIRLHDCDIGAIVNRELTQRIRPVMVLANHKPVMRHDIKIASRLVAKFDKRHNLWQRED---------------------GKDTTNPMSSNNPLLANITEYLVDEGSYXXXXXXXXXXXXXXXXTVTGSDPSNIKVEVDDKLAAVLDRLILYLRFVHSFDYYSTTEYQIEDEMPHRCGILHARGAHIHVDKPLTQKEVEEYIKSFEMKAELILNSVELLTIDEAKKLGYKTLDESVDVFIAENTQEISKDKWLCPLSGKKFKGPDFVQKHILNKHMDKVELVKQNTEFFNNYLLDPKRPQLPEHPSNRPGVKTTESGEIRNEGQF 2215
EGG A D + S++ + D+ ++ P + E E K +E + +K + +PRALH+T SIFLRNL P++ ++EIEA+ +SG+LR+A+ DP +R+++RRGW+T+ R VNIKEICW+LNN RL DC++GAIVNR+L++R+RP + HK ++R DIK+ +++ D+R LW D G TT +S NP+L NIT+YL+ L L D +E D++L +VLDRL+LYLR VHS DYY+ EY EDEMP+RCGI+HARG +T +V+EYIK+++ K + L L+ DE K+LG K + V+ F+ NTQE++KDKWLCPLSGKKFKGP+F++KHI NKH +KV+ V++ ++FNNYL DPKRPQLPEHP + K TES R G +
Sbjct: 446 EGGTALQDAAAIKSEQSDEQQEKDAEQPAELQADEPAAAKNGEEPEKTEKNEVE------TKSTADDVTETIDLDKVKDGPQPRALHRTSSIFLRNLAPSITKAEIEAICTRFSGYLRVAIADPLVERRWYRRGWITFTRDVNIKEICWSLNNQRLRDCEMGAIVNRDLSRRVRPANGITAHKQIVRADIKLCAKIAMNLDERFKLWSEADSTQQQPDAESKPSADATNGSGGSSTTYGFNSKNPVLQNITDYLI--------EEASAEEEELLGLAGDNKDGEGEPIERDEQLISVLDRLVLYLRIVHSVDYYNHCEYPYEDEMPNRCGIIHARGPPPMR---VTSNDVQEYIKAYDGKLQQFLTKSVQLSDDEIKELGAKNPETEVEKFVQANTQELAKDKWLCPLSGKKFKGPEFIRKHIFNKHEEKVDEVRKEVQYFNNYLRDPKRPQLPEHPGS---SKRTESESGRGSGGY 902 HSP 2 Score: 110.538 bits (275), Expect = 2.708e-23 Identity = 62/180 (34.44%), Postives = 97/180 (53.89%), Query Frame = 2
Query: 512 TQPPMLLFKHFLQQQDDDIEMDQAMKKYNEYKDSFVTKQLKAFFDSHSNQEWFREKYSPQFVEKRKVELEKNIQLRKEIFTYLHERNWMDNIKIHVDENDSIVRLMDAVVILLEGGNAHDLTILDSK--------RYRSESPNDSHILEDVVVKSPEKVTSSEGIEVVNKEIIEPDDKKF 1027
TQP ML K FL QD++I + M+KY EYK F +QL FF +H ++EWF+ KY P+ +R E ++ R ++F L E + ++K+ + DS+VR++D VI LEGG DL ILD K +SES ++ ++ +SP++ S +G + ++ P K
Sbjct: 154 TQPAMLTLKQFLDTQDENISDSEVMRKYTEYKTDFKRQQLNEFFVAHKDEEWFKNKYHPEDSVRRSEEQRGFLKRRTDVFLELLENGTIGSVKVDSSQADSLVRVLDTCVIKLEGGTDEDLKILDEKPKETPVVYERKSES-TEASVVAKREPESPKQTKSEKGADEEQPVVVSPQRKSL 332
BLAST of serrate RNA effector molecule vs. TrEMBL
Match: A0A0F7GYG7 (Serrate RNA effector molecule (Fragment) OS=Schmidtea mediterranea OX=79327 PE=2 SV=1) HSP 1 Score: 839.336 bits (2167), Expect = 0.000e+0 Identity = 517/522 (99.04%), Postives = 519/522 (99.43%), Query Frame = 2
Query: 980 IEVVNKEIIEPDDKKFXXXXXXXXXXXXKFEKKSELQEPRALHKTFSIFLRNLHPNVLRSEIEALVKPYSGFLRLALQDPTPDRKFFRRGWVTYDRTVNIKEICWNLNNIRLHDCDIGAIVNRELTQRIRPVMVLANHKPVMRHDIKIASRLVAKFDKRHNLWQREDGKDTTNPMSSNNPLLANITEYLVDEGSYXXXXXXXXXXXXXXXXTVTGSDPSNIKVEVDDKLAAVLDRLILYLRFVHSFDYYSTTEYQIEDEMPHRCGILHARGAHIHVDKPLTQKEVEEYIKSFEMKAELILNSVELLTIDEAKKLGYKTLDESVDVFIAENTQEISKDKWLCPLSGKKFKGPDFVQKHILNKHMDKVELVKQNTEFFNNYLLDPKRPQLPEHPSNRPGVKTTESGEIRNEGQFDNNNKRFGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGSSPNGGGYRDSXXXXXXXXXXXXXXXXXYYRKSSYPXXXXXXXXXXXXXXYYARKVLSYNDLDAPMDD 2545
IE+VNKEIIE DDKKFEEEIESTENVEEKFEKKSE QEPRALHKTFSIFLRNLHPNVLRSEIEALVKPYSGFLRLALQDPTPDRKFFRRGWVTYDRTVNIKEICWNLNNIRLHDCDIGAIVNRELTQRIRPVMVLANHKPVMRHDIKIASRLVAKFDKRHNLWQREDGKDTTNPMSSNNPLLANITEYLVDEGSYEEEALLGGNLNSNLELTVTGSDP NIKVEVDDKLAAVLDRLILYLRFVHSFDYYSTTEYQIEDEMPHRCGILHARGAHIHVDKPLTQKEVEEYIKSFEMKAELILNSVELLTIDEAKKLGYKTLDESVDVFIAENTQEISKDKWLCPLSGKKFKGPDFVQKHILNKHMDKVELVKQNTEFFNNYLLDPKRPQLPEHPSNRPGVKTTESGEIRNEGQFDNNNKRFGDNDSRNRNMDNNRNFSRRNDDFDNRRPNYRNDRGSSPNGGGYRDSGNRNNNFGDNRGG+NGNYYRKSSYPSRGSQSRQRNGGGSYYARKVLSYNDLDAPMDD
Sbjct: 2 IEIVNKEIIEADDKKFEEEIESTENVEEKFEKKSEXQEPRALHKTFSIFLRNLHPNVLRSEIEALVKPYSGFLRLALQDPTPDRKFFRRGWVTYDRTVNIKEICWNLNNIRLHDCDIGAIVNRELTQRIRPVMVLANHKPVMRHDIKIASRLVAKFDKRHNLWQREDGKDTTNPMSSNNPLLANITEYLVDEGSYEEEALLGGNLNSNLELTVTGSDPLNIKVEVDDKLAAVLDRLILYLRFVHSFDYYSTTEYQIEDEMPHRCGILHARGAHIHVDKPLTQKEVEEYIKSFEMKAELILNSVELLTIDEAKKLGYKTLDESVDVFIAENTQEISKDKWLCPLSGKKFKGPDFVQKHILNKHMDKVELVKQNTEFFNNYLLDPKRPQLPEHPSNRPGVKTTESGEIRNEGQFDNNNKRFGDNDSRNRNMDNNRNFSRRNDDFDNRRPNYRNDRGSSPNGGGYRDSGNRNNNFGDNRGGSNGNYYRKSSYPSRGSQSRQRNGGGSYYARKVLSYNDLDAPMDD 523
BLAST of serrate RNA effector molecule vs. TrEMBL
Match: A0A3B3B9F3 (Serrate RNA effector molecule homolog (Arabidopsis) OS=Oryzias melastigma OX=30732 PE=4 SV=1) HSP 1 Score: 459.529 bits (1181), Expect = 3.919e-145 Identity = 257/570 (45.09%), Postives = 365/570 (64.04%), Query Frame = 2
Query: 509 PTQPPMLLFKHFLQQQDDDIEMDQAMKKYNEYKDSFVTKQLKAFFDSHSNQEWFREKYSPQFVEKRKVELEKNIQLRKEIFTYLHERNWMDNIKIHVDENDSIVRLMDAVVILLEGGNAHDLTILDSKRYRSESPNDSHIL---------EDVVVKSPEKVTSSEG-----------IEVVNKEIIEPDDKKFXXXXXXXXXXXXKFEKKSELQEPRALHKTFSIFLRNLHPNVLRSEIEALVKPYSGFLRLALQDPTPDRKFFRRGWVTYDRTVNIKEICWNLNNIRLHDCDIGAIVNRELTQRIRPVMVLANHKPVMRHDIKIASRLVAKFDKRHNLWQ---REDGKDTTNPMSSNNPLLANITEYLVDEGSYXXXXXXXXXXXXXXXXTVTGSDPSNIKVEVDDKLAAVLDRLILYLRFVHSFDYYSTTEYQIEDEMPHRCGILHARGAHIHVDKPLTQKEVEEYIKSFEMKAELILNSVELLTIDEAKKLGYKTLDESVDVFIAENTQEISKDKWLCPLSGKKFKGPDFVQKHILNKHMDKVELVKQNTEFFNNYLLDPKRPQLPE 2149
P P M FK FL DD ++ +A+K+YNEYK F +Q++ FF +H ++EWFR KY P + K E + R +FT+L E W DN+ + ++++ +I+R++DA VI +EGG HDL ILD E+ + S EDV V S E S E +++N +++ + +E E + E+K + S PR LH+T S+F+R++ P + ++EI AL + Y GFLR+ L DP P+R+FFRR WVT+DR+VNIKE+CWNL NIRL DC++ VNR+L +R+R V + HK V+R+DIK+A++L+ D++ +LW +E+G + P S NP+L NIT+YL++E S EEE LLG + E +P+ + VE DDKLA VLDRL+LYLR VHS DYY+T EY EDEMP+RCG++H RG I ++ +T EV++++K E K + + E+L+ +EA K+G K +E V+ FI+ NTQE+ KDKWLCPLSGKKFKGP+FV+KHILNKH DK+E VK+ FFNN+L+D KRP LPE
Sbjct: 142 PPPPIMKSFKEFLLSLDDSVDETEAVKRYNEYKVDFRRQQMQDFFLAHKDEEWFRSKYHPDEASRLKAEARSAVHNRLNVFTFLMENGWFDNVSLDIEQSPAIIRVLDAAVIKMEGGTDHDLRILDMPTEEEENKDKSASASAGDQLSKREDVKVLSGEGKPSGEKDKSEKVRVYYLSKLINFLLLKSVNASPKENSEEDKKEEKKPKDDSP--RPRPLHRTCSLFMRSIAPTISKAEIIALCRRYPGFLRVCLSDPHPERRFFRRCWVTFDRSVNIKEVCWNLQNIRLRDCELAPGVNRDLARRVRNVNGITQHKQVLRNDIKLAAKLIHSLDEKGDLWSSKAQEEGPGSELPAS--NPILKNITDYLIEEVSAEEEELLGSGSGMDTEDGNKEGNPTEMTVERDDKLAKVLDRLLLYLRIVHSVDYYNTCEYPSEDEMPNRCGMIHVRGP-IPPNR-ITHGEVQQWLKMMEEKLTPLFSLKEILSEEEAGKMGRKNPEEEVEKFISANTQELGKDKWLCPLSGKKFKGPEFVRKHILNKHGDKIEEVKKEVAFFNNFLMDAKRPSLPE 705
BLAST of serrate RNA effector molecule vs. TrEMBL
Match: A0A3Q2DCY0 (Serrate RNA effector molecule homolog (Arabidopsis) OS=Cyprinodon variegatus OX=28743 PE=4 SV=1) HSP 1 Score: 455.677 bits (1171), Expect = 3.607e-143 Identity = 259/599 (43.24%), Postives = 366/599 (61.10%), Query Frame = 2
Query: 509 PTQPPMLLFKHFLQQQDDDIEMDQAMKKYNEYKDSFVTKQLKAFFDSHSNQEWFREKYSPQFVEKRKVELEKNIQLRKEIFTYLHERNWMDNIKIHVDENDSIVRLMDAVVILLEGGNAHDLTILD----------------SKRYRSESPNDSHILEDVVVKSPEKVTSSEGIEVVNKEIIEPDDKKFXXXXXXXXXXXXKFEKKS---ELQEPR------------------------------ALHKTFSIFLRNLHPNVLRSEIEALVKPYSGFLRLALQDPTPDRKFFRRGWVTYDRTVNIKEICWNLNNIRLHDCDIGAIVNRELTQRIRPVMVLANHKPVMRHDIKIASRLVAKFDKRHNLWQ---REDGKDTTNPMSSNNPLLANITEYLVDEGSYXXXXXXXXXXXXXXXXTVTGSDPSNIKVEVDDKLAAVLDRLILYLRFVHSFDYYSTTEYQIEDEMPHRCGILHARGAHIHVDKPLTQKEVEEYIKSFEMKAELILNSVELLTIDEAKKLGYKTLDESVDVFIAENTQEISKDKWLCPLSGKKFKGPDFVQKHILNKHMDKVELVKQNTEFFNNYLLDPKRPQLPE 2149
P P M FK FL DD ++ +A+K+YNEYK F +Q++ FF +H ++EWFR KY P + K E + ++ R +F +L E W DN+ + +D+ +I++++DA VI +EGG HDL ILD S+ D ++ S EK + + EV + +E D E +V+E+ EK++ E EP+ LHKTFS+F+R++ P + ++EI AL + Y GFLR+ L DP P+R+FFRR WVT+DR+VNIKEICWNL NIRL DC++ VNR+L +R+R V + HK V+R+DIK+A++L+ D++ +LW +EDG+ T P + NP+L NIT+YL++E S EEE LLG + E + +P+ + VE DDKLA VLDRL+LYLR VHS DYY+T EY EDEMP+RCG++H RG + ++ +T EV+++ K E K + N E+L+ +EA K+G K DE V+ FI+ NTQE+ KDKWLCPLSGKKFKGP+FV+KHILNKH +K+E VK+ FFNN+L+D KRP LPE
Sbjct: 143 PPPPIMKSFKEFLLSLDDTVDETEAVKRYNEYKIDFRRQQMQDFFLAHKDEEWFRSKYHPDEASRLKAEAQSSLCNRLNVFMFLMENGWFDNVSLDIDQTPAIIKVLDAAVIKMEGGTDHDLRILDMPPEEEEEREKSASASGGGGESQRREDQKAVDRQRKPSGEKDKTEKVCEVFCWQTMEEGDSGGAEAKADGLDVKEEAEKEAVREEKPEPKKVIFSSKPKQNDEEEKKEEKKPKDDSPRPRPLHKTFSLFMRSIAPTISKAEIVALCRRYPGFLRVCLSDPHPERRFFRRCWVTFDRSVNIKEICWNLQNIRLRDCELAPGVNRDLARRVRNVNGITQHKQVLRNDIKLAAKLIHALDEKGDLWSNKAQEDGQSTELP--AQNPILKNITDYLIEEVSAEEEELLGSGSGMDPEESAKEGNPAELTVERDDKLAKVLDRLLLYLRIVHSVDYYNTCEYPSEDEMPNRCGMIHVRGP-VPPNR-VTHGEVQQWEKVIEEKLMPLFNLKEVLSEEEAVKMGRKDPDEEVEKFISANTQELGKDKWLCPLSGKKFKGPEFVRKHILNKHGEKIEEVKKEVLFFNNFLMDAKRPSLPE 737
BLAST of serrate RNA effector molecule vs. TrEMBL
Match: J9K6M8 (Uncharacterized protein OS=Acyrthosiphon pisum OX=7029 PE=4 SV=1) HSP 1 Score: 449.899 bits (1156), Expect = 6.048e-142 Identity = 247/566 (43.64%), Postives = 352/566 (62.19%), Query Frame = 2
Query: 512 TQPPMLLFKHFLQQQDDDIEMDQAMKKYNEYKDSFVTKQLKAFFDSHSNQEWFREKYSPQFVEKRKVELEKNIQLRKEIFTYLHERNWMDNIKIHVDENDSIVRLMDAVVILLEGGNAHDLTILDSKRYRSESPNDSHILEDVVVKSPEKVTSSEGIEVVNKEIIEPDDKK------FXXXXXXXXXXXXKFEKKSELQEPRALHKTFSIFLRNLHPNVLRSEIEALVKPYSGFLRLALQDPTPDRKFFRRGWVTYDRTVNIKEICWNLNNIRLHDCDIGAIVNRELTQRIRPVMVLANHKPVMRHDIKIASRLVAKFDKRHNLWQREDGK----DTTNPMSSNNPLLANITEYLVDEGSYXXXXXXXXXXXXXXXXTVTGSDPSNIKVEVDDKLAAVLDRLILYLRFVHSFDYYSTTEYQIEDEMPHRCGILHARGAHIHVDKPLTQKEVEEYIKSFEMKA-ELILNSVELLTIDEAKKLGYKTLDESVDVFIAENTQEISKDKWLCPLSGKKFKGPDFVQKHILNKHMDKVELVKQNTEFFNNYLLDPKRPQLPEHPSNRPGVK 2176
TQPPM+ K FL QDD+I ++A+ KYNEYK F QL FF +H ++EWF+ KY P KRK E ++ R E+F E ++++ + D + +V L+D+VVI LEGG DLT+L+ K IL+ PEK + + I E D K + + ++ ++ ++ +PRALH+T S+FLRNL P + +SE+E + K + GF+RL++ DP P+R++FRRGWVT+DR VNIKEICWNLN++RL D ++GAIVNR+L++RIR V + NH+ V R+D+K+ + ++ FD R LWQ DG+ + T + S NP+L NIT++L+ EEA T D E D +L LD+++LYLR VHS D+Y+ +EY EDEMP+RCGI+HAR A P TQ+E+ +Y +F+ KA L +++ ++ E +LG K +E ++ F+ NTQEISKDKWLCPLSGKKFKGP+FV+KHI NKH+DK++ VK+ ++FNNYL DPKRPQLPEHP ++ G K
Sbjct: 141 TQPPMMSLKSFLITQDDNITDEEALAKYNEYKLQFKRNQLNEFFVAHKDEEWFKIKYHPDDSVKRKEEQTIALKKRLEVFKEFLENGKVESVCVDADNPEPLVHLLDSVVIKLEGGTDFDLTVLNPK----------EILKAKQEPEPEKKETDKKINAGGNSDGEVDSDKEDEAMDVDGQKPEVLDITNDSDQNDDVVKPRALHRTTSVFLRNLAPAITKSELETICKRFPGFIRLSIADPLPERRWFRRGWVTFDRDVNIKEICWNLNSVRLRDSELGAIVNRDLSKRIRSVNGVTNHRQVARNDMKLCASIINNFDNRSGLWQLTDGEQPASEKTYGVVSRNPVLHNITDFLI------EEASAEEEELLGENATCEPED----NTEKDLQLFKALDKMLLYLRIVHSVDFYNHSEYVNEDEMPNRCGIMHARCA--LPSNPPTQQEITDYCNNFQTKANSLTVSTSHEVSEKELMQLGAKHEEEEIEKFVTSNTQEISKDKWLCPLSGKKFKGPEFVRKHIFNKHIDKLDDVKKEVKYFNNYLRDPKRPQLPEHPGSKQGRK 684
BLAST of serrate RNA effector molecule vs. TrEMBL
Match: A0A423U785 (Arsenite-resistance protein 2-like protein OS=Penaeus vannamei OX=6689 GN=C7M84_022254 PE=4 SV=1) HSP 1 Score: 444.121 bits (1141), Expect = 1.884e-139 Identity = 257/588 (43.71%), Postives = 363/588 (61.73%), Query Frame = 2
Query: 509 PTQPPMLLFKHFLQQQDDDIEMDQAMKKYNEYKDSFVTKQLKAFFDSHSNQEWFREKYSPQFVEKRKVELEKNIQLRKEIFTYLHERNWMDNIKIHVDENDSIVRLMDAVVILLEGGNAHDLTILDSKRYRSESPNDSHILEDVVVKSPEKVTSSEGIEVVNKEII--------------------EPDDKKFXXXXXXXXXXXXKF--------EKKSELQEPRALHKTFSIFLRNLHPNVLRSEIEALVKPYSGFLRLALQDPTPDRKFFRRGWVTYDRTVNIKEICWNLNNIRLHDCDIGAIVNRELTQRIRPVMVLANHKPVMRHDIKIASRLVAKFDKRHNLWQREDGKDTTNPM----SSNNPLLANITEYLVDEGSYXXXXXXXXXXXXXXXXTVTGSDPSNIKVEVDDKLAAVLDRLILYLRFVHSFDYYSTTEYQIEDEMPHRCGILHARGAHIHVDKPLTQKEVEEYIKSFEMKAELILNSVELLTIDEAKKLGYKTLDESVDVFIAENTQEISKDKWLCPLSGKKFKGPDFVQKHILNKHMDKVELVKQNTEFFNNYLLDPKRPQLPEHPSNRPGVK 2176
PTQPPM+ FK F++Q DD I ++A++KY++YK F +QL FF +H +EWF+ KY P+ KR+ E N++ R +F L E N M+NI + D++D +++L+D+VVI LEGG DL +LD ++PE+ S+ IE K I EP EE + +++ EK++ ++ + SIFLRNL P + + E+EA+ + Y+GFLR A+ DP P+R++FRRGWVT+ R VNIK+ICWNLNNIRL DC++GAIVNR+L++RIR V + +H+ V+R DIK++++++ D R LW E ++ N + SS+NP+L NIT+YL++E S EEE LLG N S + +E D L VLDRL+LYLR VHS DYY+ +EY EDEMP+RCGI+HARG I +T +EV++Y ++FE K L + L+ DEAKKLG K +E V+ F+ NTQE++KDKW CPL GKKFKG ++V KHIL KH +KV+ VK+ ++FNNYL DPKRPQLPE+P N+ G +
Sbjct: 139 PTQPPMMTFKAFMEQCDDSISEEEALRKYSDYKLEFKRQQLNEFFINHKEEEWFKAKYHPEECVKRRDEQLSNLKRRVSVFCELFEMNRMENISVDADQSDQLLKLLDSVVIKLEGGTDLDLQVLD--------------------QAPEEDVKSQPIEEEKKPFILGEDSDEGEEKEKSEEKNPDEPLKMDMSEEQMELQKKAKEYLKQKVNEGEKETRKRKHSGSSSSTSIFLRNLAPTITKQEVEAMCRRYNGFLRAAIADPQPERRWFRRGWVTFKRDVNIKDICWNLNNIRLRDCELGAIVNRDLSRRIRTVNGITSHRSVVRSDIKLSAKIIQNLDSRWGLWI-ESTENLDNALLSLTSSSNPVLRNITDYLIEEASAEEEELLGANDASANNSEEKAEGEA---IERDPSLIKVLDRLLLYLRIVHSVDYYNHSEYPNEDEMPNRCGIMHARG--IPPSSKVTPQEVQDYCRAFENKIGSFLQPLTKLSDDEAKKLGLKEAEEEVEKFVQSNTQEVAKDKWQCPLCGKKFKGAEYVHKHILIKHAEKVKEVKKEVDYFNNYLRDPKRPQLPEYPGNKHGGR 700
BLAST of serrate RNA effector molecule vs. Ensembl Cavefish
Match: srrt (serrate RNA effector molecule homolog (Arabidopsis) [Source:NCBI gene;Acc:192311]) HSP 1 Score: 370.933 bits (951), Expect = 6.761e-114 Identity = 186/354 (52.54%), Postives = 249/354 (70.34%), Query Frame = 2
Query: 1094 PRALHKTFSIFLRNLHPNVLRSEIEALVKPYSGFLRLALQDPTPDRKFFRRGWVTYDRTVNIKEICWNLNNIRLHDCDIGAIVNRELTQRIRPVMVLANHKPVMRHDIKIASRLVAKFDKRHNLWQREDGKDT--TNPMSSNNPLLANITEYLVDEGSYXXXXXXXXXXXXXXXXTVTGSDPSNIKVEVDDKLAAVLDRLILYLRFVHSFDYYSTTEYQIEDEMPHRCGILHARGAHIHVDKPLTQKEVEEYIKSFEMKAELILNSVELLTIDEAKKLGYKTLDESVDVFIAENTQEISKDKWLCPLSGKKFKGPDFVQKHILNKHMDKVELVKQNTEFFNNYLLDPKRPQLPE 2149
PR LHKT S+F+R++ P + ++EI AL + Y GF+R+ L DP P+R+FFRR WVT+DR VNIK+ICWNL NIRL DC++ VNR+L +R+R + + HK V+R+DIK+A++L+ D R LW D + + NP+L NIT+YL+DE S EEE LLG ++ E +P+ I VE D+KL VLDRL+ YLR VHS DYY+ EY EDEMP+RCGI+H RG I ++ +T +EV ++ K+FE K L+ + E L+ DEA K+G K ++ V+ F+ NTQE+ KDKWLCPLSGKKFKGP+FV+KHILNKH DK+E VK+ EFFNN+L+D KRP LPE
Sbjct: 422 PRPLHKTSSLFMRSIAPTISKAEIVALCRRYPGFMRVCLSDPQPERRFFRRCWVTFDRAVNIKDICWNLQNIRLRDCELAPGVNRDLARRVRNINGITQHKQVLRNDIKLAAKLIHSLDDREALWSPRPSGDAPVAVEIPAQNPILKNITDYLIDEVSAEEEELLGSVGGADSEEGAKEGNPTEITVERDEKLVKVLDRLLFYLRIVHSIDYYNCCEYPSEDEMPNRCGIIHVRGP-IPPNR-ITHREVGDWEKTFEEKLVLLFSVKETLSEDEAVKMGRKAPEQEVEKFVTANTQELGKDKWLCPLSGKKFKGPEFVRKHILNKHGDKIEEVKKEVEFFNNFLMDAKRPSLPE 773 HSP 2 Score: 106.301 bits (264), Expect = 5.280e-23 Identity = 49/126 (38.89%), Postives = 77/126 (61.11%), Query Frame = 2
Query: 509 PTQPPMLLFKHFLQQQDDDIEMDQAMKKYNEYKDSFVTKQLKAFFDSHSNQEWFREKYSPQFVEKRKVELEKNIQLRKEIFTYLHERNWMDNIKIHVDENDSIVRLMDAVVILLEGGNAHDLTILD 886
P P M FK FL DD ++ +++K+YNEYK F +Q++ FF +H ++EWFR KY P KRK + +Q R +F L E +W D++ + +D I++++DA VI +EGG +D+ IL+
Sbjct: 148 PPPPVMKSFKEFLLSLDDSVDETESVKRYNEYKIEFRRQQMQDFFLAHKDEEWFRSKYHPDESSKRKADAHAALQNRLNVFMDLMENSWFDSVSMDIDRAPQILKILDAAVIKMEGGTENDMRILE 273
BLAST of serrate RNA effector molecule vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010621.1 (pep scaffold:Pmarinus_7.0:GL476849:23359:42927:-1 gene:ENSPMAG00000009614.1 transcript:ENSPMAT00000010621.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 345.51 bits (885), Expect = 1.594e-105 Identity = 174/362 (48.07%), Postives = 246/362 (67.96%), Query Frame = 2
Query: 1091 EPRALHKTFSIFLRNLHPNVLRSEIEALVKPYSGFLRLALQDPTPDRKFFRRGWVTYDRTVNIKEICWNLNNIRLHDCDIGAIVNRELTQRIRPVMVLANHKPVMRHDIKIASRLVAKFDKRHNLW---QREDGKDTTNPMSSNNPLLANITEYLVDEGSYXXXXXXXXXXXXXXXXTVTGSD-----PSNIKVEVDDKLAAVLDRLILYLRFVHSFDYYSTTEYQIEDEMPHRCGILHARGAHIHVDKPLTQKEVEEYIKSFEMKAELILNSVELLTIDEAKKLGYKTLDESVDVFIAENTQEISKDKWLCPLSGKKFKG-PDFVQKHILNKHMDKVELVKQNTEFFNNYLLDPKRPQLPE 2149
+PRALH+T S+F+RN+ PN+ +SEI A+ K Y GF+R+AL DP +R+F+RRGWVT++R+VNIKEICW+L NIRL +C++ +VNR+L +R+R V + HKPV+R+DI++A++L+ D++ LW Q D P SS NP+L NIT+YL++E S + L +TGSD S++ +E D KL VLDRL+LYLR VHS DYY+ EYQ EDEMP+RCG++H RG + ++ T EV EY + E + +LN+ + T +EA K+G K ++ V+ ++ NTQE+ KDKW+CP SGKKFK +F++KHI NKH DK+ V++ FFNNYL+D KRP PE
Sbjct: 382 KPRALHRTCSLFMRNIAPNIPKSEIVAIFKRYPGFVRVALSDPQIERRFYRRGWVTFERSVNIKEICWSLQNIRLRECELSPVVNRDLARRVRGVQGITQHKPVVRNDIRLAAKLIQALDQKAQLWSATQPIKDTDILAPFSSQNPILKNITDYLIEEVS--------AEEDELLGNAITGSDEPKDSTSDVPLERDGKLLQVLDRLVLYLRIVHSVDYYNACEYQNEDEMPNRCGMIHVRGP-LPTNR-ATHNEVTEYERQQEERLAPLLNARDTPTPEEAIKMGKKDPEQEVEKYVQGNTQEVGKDKWVCPFSGKKFKEIMEFLRKHIFNKHADKLGEVQREVGFFNNYLMDLKRPGPPE 733 HSP 2 Score: 101.679 bits (252), Expect = 2.570e-22 Identity = 52/138 (37.68%), Postives = 82/138 (59.42%), Query Frame = 2
Query: 479 IPKSDDTPNYPTQPPMLLFKHFLQQQDDDIEMDQAMKKYNEYKDSFVTKQLKAFFDSHSNQEWFREKYSPQFVEKRKVELEKNIQLRKEIFTYLHERNWMDNIKIHVDENDSIVRLMD--AVVILLEGGNAHDLTILD 886
+P+ + P YP M FK FL + ++ +A+++YN YK F +QL FF +H ++EWFR KY P+ KRK E +Q R + FT+L E W ++I + +D+++ I+R++D A VI +EGG DL +D
Sbjct: 126 VPEVEAPPAYPI---MKTFKEFLLSIAESVDETEAVRRYNNYKIEFRRQQLHEFFMAHKDEEWFRVKYHPEESAKRKHEAASALQHRLKAFTFLLEGGWFNSISLDIDKSEQIIRVLDAGAAVIKMEGGTDLDLQTVD 260
BLAST of serrate RNA effector molecule vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001670.1 (pep scaffold:Pmarinus_7.0:GL480784:6169:22985:1 gene:ENSPMAG00000001502.1 transcript:ENSPMAT00000001670.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 155.606 bits (392), Expect = 4.347e-40 Identity = 69/161 (42.86%), Postives = 111/161 (68.94%), Query Frame = 2
Query: 1070 EKKSELQEPRALHKTFSIFLRNLHPNVLRSEIEALVKPYSGFLRLALQDPTPDRKFFRRGWVTYDRTVNIKEICWNLNNIRLHDCDIGAIVNRELTQRIRPVMVLANHKPVMRHDIKIASRLVAKFDKRHNLWQREDGKDTTNPMSSN--NPLLANITEYL 1546
E++ L PR H+ SIFLRN+ P + ++EI +L + + GF+R+AL +P P+R F+RRGWVT+ VNI++ICWNL N++L +C++ +VNR+L +R+R V ++ H V R+ +++A +LV D+R LW+ +G TT P +S+ NPLL +++YL
Sbjct: 415 EEQGLLPRPRNFHRNMSIFLRNIAPYISKAEIVSLCRRFPGFMRVALSEPQPERGFYRRGWVTFSGHVNIQDICWNLQNVKLRECELSPVVNRDLARRMRIVSGVSLHATVARNHLRLALKLVHALDRRAKLWEYTEG--TTIPGTSDGANPLLGGLSKYL 573 HSP 2 Score: 83.9593 bits (206), Expect = 5.710e-17 Identity = 47/123 (38.21%), Postives = 72/123 (58.54%), Query Frame = 2
Query: 524 MLLFKHFLQQQDDDIEMDQAMKKYNEYKDSFVTKQLKAFFDSHSNQEWFREKYSPQFVEKRKVELEKNIQLRKEIFTYLHERNWMDNIKIHVDENDSIVRLMDA---VVILLEGGNAHDLTIL 883
M FK FL DD +E +A+K Y+EYK F +Q++ FF +H +EWFR +Y P EKR+ ++ + + R +F L + W+DN+ + +D+ D I +DA +L+EGG A DL L
Sbjct: 142 MKSFKEFLVTLDDAVEETEAVKLYSEYKQEFQQQQMQDFFLAHKGEEWFRTRYHPDEREKRRRDIIASARHRVAVFCMLKQHKWLDNVTLDLDKTDQIAHFLDAARTASMLMEGGTAEDLKAL 264
BLAST of serrate RNA effector molecule vs. Ensembl Nematostella
Match: EDO46264 (Ars2/serrate-like protein; Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQB5]) HSP 1 Score: 308.145 bits (788), Expect = 3.020e-89 Identity = 156/381 (40.94%), Postives = 231/381 (60.63%), Query Frame = 2
Query: 1094 PRALHKTFSIFLRNLHPNVLRSEIEALVKPYSGFLRLALQDPTPDRKFFRRGWVTYDRTVNIKEICWNLNNIRLHDCDIGAIVNRELTQRIRPVMVLANHKPVMRHDIKIASRLVAKFDKRHNLWQREDGKDTTNP-----------------------------MSSNNPLLANITEYLVDEGSYXXXXXXXXXXXXXXXXTVTGSDPSNIKVEVDDKLAAVLDRLILYLRFVHSFDYYSTTEYQIEDEMPHRCGILHARGAHIHVDKPLTQKEVEEYIKSFEMKAELILNSVELLTIDEAKKLGYKTLDESVDVFIAENTQEISKDKWLCPLSGKKFKGPDFVQKHILNKHMDKVELVKQNTEFFNNYLLDPKRPQLPE 2149
PR LHKT+S+F+RN+ P++ +++I A K + GFLR+AL DP+PDR+F+RRGW+T+DR+V+IK+I W+ NNIR+ + ++ ++NR+L++RIRPV + K V+R IK+A+ L+ DK+ +++++ K + + NP+LA+++E + + EE L D S + D L VLDR++LYLR VHS DYY+ +Y EDEMP+RCGI+H RG V + T E E+ K+ + K EL L E + +E KLG + + ++ F+ NTQE++KDKWLCPLSGKKF+GP+FV+KHI NKH D+VE V+ EFFN ++ DPKRP PE
Sbjct: 693 PRPLHKTYSLFMRNIPPSISKADIAAACKRFPGFLRVALSDPSPDRRFYRRGWITFDRSVDIKQINWDFNNIRIKEAELNPVINRDLSRRIRPVNGITQAKQVVRESIKLAADLIRVLDKKSAVYEKDQEKQEEQNGKEKETAEKKEEGEEGEEKPAEEKEPPLNIPNENPILASLSEDV----AEEEGGEEMELLGKGSPPADGDGDKSEVDFTQDPALLRVLDRMLLYLRVVHSMDYYNCGDYPHEDEMPNRCGIMHVRGP---VPEKATLAEAHEWQKNTKQKLELFLQEKETVPDEEILKLGKRDPESEIEKFVEANTQELAKDKWLCPLSGKKFRGPEFVRKHIFNKHADQVEEVRMEVEFFNRFIADPKRPANPE 1066 HSP 2 Score: 109.383 bits (272), Expect = 2.812e-24 Identity = 57/136 (41.91%), Postives = 82/136 (60.29%), Query Frame = 2
Query: 509 PTQPPMLLFKHFLQQQDDDIEMDQAMKKYNEYKDSFVTKQLKAFFDSHSNQEWFREKYSPQFVEKRKVELEKNIQLRKEIFTYLHERNWMDNIKIHVDENDSIVRLMDAVVILLEGGNAHDLTILDSKRYRSESPN 916
P P M K FL QDD+I+ +A+ KY YK F QL FF H ++EWFR +Y P+ +R+ EL+++++ R F L E ++++ VD +D+IV+ +DAVVI LEGG+ DL ILD RS SP+
Sbjct: 149 PPGPVMQTLKQFLATQDDNIDDMEAICKYQAYKLDFKKTQLNDFFQQHKDEEWFRMRYHPREAAQRQKELQRSVRCRLNCFLELMEMELSKDLRLEVDHSDAIVKFLDAVVIKLEGGSDEDLAILD----RSPSPS 280
BLAST of serrate RNA effector molecule vs. Ensembl Medaka
Match: srrt (serrate, RNA effector molecule [Source:NCBI gene;Acc:101166978]) HSP 1 Score: 369.007 bits (946), Expect = 2.497e-113 Identity = 190/361 (52.63%), Postives = 260/361 (72.02%), Query Frame = 2
Query: 1076 KSELQEPRALHKTFSIFLRNLHPNVLRSEIEALVKPYSGFLRLALQDPTPDRKFFRRGWVTYDRTVNIKEICWNLNNIRLHDCDIGAIVNRELTQRIRPVMVLANHKPVMRHDIKIASRLVAKFDKRHNLW---QREDGKDTTNPMSSNNPLLANITEYLVDEGSYXXXXXXXXXXXXXXXXTVTGSDPSNIKVEVDDKLAAVLDRLILYLRFVHSFDYYSTTEYQIEDEMPHRCGILHARGAHIHVDKPLTQKEVEEYIKSFEMKAELILNSVELLTIDEAKKLGYKTLDESVDVFIAENTQEISKDKWLCPLSGKKFKGPDFVQKHILNKHMDKVELVKQNTEFFNNYLLDPKRPQLPE 2149
K + PR LH+T S+F+R++ P++ ++EI AL + Y GFLR+ L DP P+R+FFRR WVT+DR+VNIKE+CWNL NIRL DC++ VNR+L +R+R V + HK V+R+DIK+A++L+ D++ +LW +E+G + P S NP+L NIT+YL++E S EEE LLG + E +P+ + VE DDKLA VLDRL+LYLR VHS DYY+T EY EDEMP+RCG++H RG I ++ +T EV++++K E K + + E+L+ +EA K+G K +E V+ FI+ NTQE+ KDKWLCPLSGKKFKGP+FV+KHILNKH DKVE VK+ FFNN+L+D KRP LPE
Sbjct: 417 KDDSPRPRPLHRTCSLFMRSIAPSISKAEIIALCRRYPGFLRVCLSDPHPERRFFRRCWVTFDRSVNIKEVCWNLQNIRLRDCELAPGVNRDLARRVRNVNGITQHKQVLRNDIKLAAKLIHALDEKGDLWGSKAQEEGPGSELPAS--NPILKNITDYLIEEVSAEEEELLGSGSGMDTEDNNKEGNPAEMTVERDDKLAKVLDRLVLYLRIVHSVDYYNTCEYPSEDEMPNRCGMIHVRGP-IPPNR-ITHGEVQQWLKMMEEKLTPLFSLKEMLSEEEAVKMGRKNPEEEVEKFISANTQELGKDKWLCPLSGKKFKGPEFVRKHILNKHGDKVEEVKKEVAFFNNFLMDAKRPSLPE 773 HSP 2 Score: 114.005 bits (284), Expect = 1.891e-25 Identity = 52/126 (41.27%), Postives = 78/126 (61.90%), Query Frame = 2
Query: 509 PTQPPMLLFKHFLQQQDDDIEMDQAMKKYNEYKDSFVTKQLKAFFDSHSNQEWFREKYSPQFVEKRKVELEKNIQLRKEIFTYLHERNWMDNIKIHVDENDSIVRLMDAVVILLEGGNAHDLTILD 886
P P M FK FL DD ++ +A+K+YNEYK F +Q++ FF +H ++EWFR KY P + K E + R +FT+L E W D++ + ++++ I+R++DA VI +EGG HDL ILD
Sbjct: 142 PPPPIMKSFKEFLLSLDDSVDETEAVKRYNEYKVDFRRQQMQDFFLAHKDEEWFRSKYHPDEASRLKAEARSALHNRLNVFTFLMENGWFDHVSLDIEQSPVIIRVLDAAVIKMEGGTDHDLRILD 267
BLAST of serrate RNA effector molecule vs. Planmine SMEST
Match: SMESG000030605.1 (SMESG000030605.1) HSP 1 Score: 1327.38 bits (3434), Expect = 0.000e+0 Identity = 791/796 (99.37%), Postives = 794/796 (99.75%), Query Frame = 2
Query: 158 MADSEEECDTWRNRDKYPKEREEVKAKSPSPVEQRNEVRNDKRSFNSYQSPNKSIEPPFKRQRREGDEYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXIPKSDDTPNYPTQPPMLLFKHFLQQQDDDIEMDQAMKKYNEYKDSFVTKQLKAFFDSHSNQEWFREKYSPQFVEKRKVELEKNIQLRKEIFTYLHERNWMDNIKIHVDENDSIVRLMDAVVILLEGGNAHDLTILDSKRYRSESPNDSHILEDVVVKSPEKVTSSEGIEVVNKEIIEPDDKKFXXXXXXXXXXXXKFEKKSELQEPRALHKTFSIFLRNLHPNVLRSEIEALVKPYSGFLRLALQDPTPDRKFFRRGWVTYDRTVNIKEICWNLNNIRLHDCDIGAIVNRELTQRIRPVMVLANHKPVMRHDIKIASRLVAKFDKRHNLWQREDGKDTTNPMSSNNPLLANITEYLVDEGSYXXXXXXXXXXXXXXXXTVTGSDPSNIKVEVDDKLAAVLDRLILYLRFVHSFDYYSTTEYQIEDEMPHRCGILHARGAHIHVDKPLTQKEVEEYIKSFEMKAELILNSVELLTIDEAKKLGYKTLDESVDVFIAENTQEISKDKWLCPLSGKKFKGPDFVQKHILNKHMDKVELVKQNTEFFNNYLLDPKRPQLPEHPSNRPGVKTTESGEIRNEGQFDNNNKRFGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGSSPNGGGYRDSXXXXXXXXXXXXXXXXXYYRKSSYPXXXXXXXXXXXXXXYYARKVLSYNDLDAPMDD 2545
MADSEEECDTWRNRDKYPKEREEVKAKSPSPVEQRNEVRNDKRSFNSYQSPNKSIEPPFKRQRREGDEYNNNFNSN+N NPHNRDNKDFRDNRRESSFDNRFNSNSSIPKSDDTPNYPTQPPMLLFKHFLQQQDDDIEMDQAMKKYNEYKDSFVTKQLKAFFDSHSNQEWFREKYSPQFVEKRKVELEKNIQLRKEIFTYLHERNWMDNIKIHVDENDSIVRLMDAVVILLEGGNAHDLTILDSKRYRSESPNDSHILEDVVVKSPEKVTSSE IE+VNKEIIEPDDKKFEEEIESTENVEEKFEKKSELQEPRALHKTFSIFLRNLHPNVLRSEIEALVKPYSGFLRLALQDPTPDRKFFRRGWVTYDRTVNIKEICWNLNNIRLHDCDIGAIVNRELTQRIRPVMVLANHKPVMRHDIKIASRLVAKFDKRHNLWQREDGKDTTNPMSSNNPLLANITEYLVDEGSYEEEALLGGNLNSNLELTVTGSDPSNIKVEVDDKLAAVLDRLILYLRFVHSFDYYSTTEYQIEDEMPHRCGILHARGAHIHVDKPLTQKEVEEYIKSFEMKAELILNSVELLTIDEAKKLGYKTLDESVDVFIAENTQEISKDKWLCPLSGKKFKGPDFVQKHILNKHMDKVELVKQNTEFFNNYLLDPKRPQLPEHPSNRPGVKTTESGEIRNEGQFDNNNKRFGDNDSRNRNMDNNRNFSRRNDDFDNRRPNYRNDRGSSPNGGGYRDSGNRNNNFGDNRGG+NGNYYRKSSYPSRGSQSRQRNGGGSYYARKVLSYNDLDAPMDD
Sbjct: 1 MADSEEECDTWRNRDKYPKEREEVKAKSPSPVEQRNEVRNDKRSFNSYQSPNKSIEPPFKRQRREGDEYNNNFNSNINSNPHNRDNKDFRDNRRESSFDNRFNSNSSIPKSDDTPNYPTQPPMLLFKHFLQQQDDDIEMDQAMKKYNEYKDSFVTKQLKAFFDSHSNQEWFREKYSPQFVEKRKVELEKNIQLRKEIFTYLHERNWMDNIKIHVDENDSIVRLMDAVVILLEGGNAHDLTILDSKRYRSESPNDSHILEDVVVKSPEKVTSSEEIEIVNKEIIEPDDKKFEEEIESTENVEEKFEKKSELQEPRALHKTFSIFLRNLHPNVLRSEIEALVKPYSGFLRLALQDPTPDRKFFRRGWVTYDRTVNIKEICWNLNNIRLHDCDIGAIVNRELTQRIRPVMVLANHKPVMRHDIKIASRLVAKFDKRHNLWQREDGKDTTNPMSSNNPLLANITEYLVDEGSYEEEALLGGNLNSNLELTVTGSDPSNIKVEVDDKLAAVLDRLILYLRFVHSFDYYSTTEYQIEDEMPHRCGILHARGAHIHVDKPLTQKEVEEYIKSFEMKAELILNSVELLTIDEAKKLGYKTLDESVDVFIAENTQEISKDKWLCPLSGKKFKGPDFVQKHILNKHMDKVELVKQNTEFFNNYLLDPKRPQLPEHPSNRPGVKTTESGEIRNEGQFDNNNKRFGDNDSRNRNMDNNRNFSRRNDDFDNRRPNYRNDRGSSPNGGGYRDSGNRNNNFGDNRGGSNGNYYRKSSYPSRGSQSRQRNGGGSYYARKVLSYNDLDAPMDD 796
BLAST of serrate RNA effector molecule vs. Planmine SMEST
Match: SMESG000023055.1 (SMESG000023055.1) HSP 1 Score: 580.096 bits (1494), Expect = 0.000e+0 Identity = 293/584 (50.17%), Postives = 422/584 (72.26%), Query Frame = 2
Query: 503 NYPTQPPMLLFKHFLQQQDDDIEMDQAMKKYNEYKDSFVTKQLKAFFDSHSNQEWFREKYSPQFVEKRKVELEKNIQLRKEIFTYLHERNWMDNIKIHVDENDSIVRLMDAVVILLEGGNAHDLTILDSKRYRSESPNDSHILEDVVVK-------------------SPEKVTSS-------EGIEVVNKEIIEPDDKKFXXXXXXXXXXXXKFEKKSELQEPRALHKTFSIFLRNLHPNVLRSEIEALVKPYSGFLRLALQDPTPDRKFFRRGWVTYDRTVNIKEICWNLNNIRLHDCDIGAIVNRELTQRIRPVMVLANHKPVMRHDIKIASRLVAKFDKRHNLWQREDGKDTTNPMSSNNPLLANITEYLVDEGSYXXXXXXXXXXXXXXXXTVTGS---DPSNIKVEVDDKLAAVLDRLILYLRFVHSFDYYSTTEYQIEDEMPHRCGILHARGAHIHVDKPLTQKEVEEYIKSFEMKAELILNSVELLTIDEAKKLGYKTLDESVDVFIAENTQEISKDKWLCPLSGKKFKGPDFVQKHILNKHMDKVELVKQNTEFFNNYLLDPKRPQLPEHPSNRP 2167
NY TQPPMLLFKHFL QQ+D+I ++ AM+KYNEYK++F +QL++FF++H ++EWF EKY P ++E ++ + +NI RK++F +L+E +MD + +H++ DS+ +L+D+ VILLEGG +DL +L+ K YR++SP + I D+ K S ++TS G E + +++ K+ EI+S E + E +E +PR LHK+ S+F++N+HP V RS++E LVKP+ G++R+ALQDP P+RKF RRGWVT++R+ ++K + W LN +L D D+GA+VN+E++QRIRP + NH+ VMR D+K A++LVAKFDKR +LW+ ++ NPLL NITE+LVDEGSYEEEA LGG+++SNL +T G DP+NI+++ D LA VLDRL+LYLR VHS+DYYS TEY+IED +P+RCG+LHARG ++ D+ L+Q +E+Y+K FE+KAEL+L+S++ L A +LG K ++E+V+ FI +NT+EI+ +KWLCPLSGKKFKGPD+V+KHILNK+ D+++ VKQ +FFNNY+LDP+RPQLPEHPSNRP
Sbjct: 61 NYITQPPMLLFKHFLNQQEDNILVEDAMRKYNEYKEAFACEQLQSFFETHKDEEWFMEKYHPDYIEAKEFKRLENIDSRKKVFMWLYENKYMDEVSVHINYQDSLFKLLDSAVILLEGGTENDLRVLEKKVYRADSPERTEIKIDIKSKNDPSSLKWDDFNTSSGDDDSDVEITSGVKASDRDSGRESDREAVVDVPKKELSPEIKSPEEMMANDELPAEGVDPRPLHKSCSVFIKNIHPKVFRSQLEELVKPFPGYVRIALQDPMPERKFLRRGWVTFERSSDVKNVVWELNKAKLLDVDLGAVVNKEISQRIRPTQPVTNHRAVMRQDVKYAAKLVAKFDKRRHLWESDNDA---------NPLLCNITEHLVDEGSYEEEAYLGGDISSNLAITGRGGSTNDPNNIRMDEDLDLARVLDRLVLYLRIVHSYDYYSATEYEIEDFLPNRCGLLHARGNLLYPDQRLSQAHLEKYMKDFEIKAELVLDSIDNLDFVVASRLGVKGIEEAVEKFITDNTKEITTEKWLCPLSGKKFKGPDYVRKHILNKYADRIDNVKQTVQFFNNYILDPRRPQLPEHPSNRP 635 The following BLAST results are available for this feature:
BLAST of serrate RNA effector molecule vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of serrate RNA effector molecule vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 2
BLAST of serrate RNA effector molecule vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of serrate RNA effector molecule vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 2
BLAST of serrate RNA effector molecule vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of serrate RNA effector molecule vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of serrate RNA effector molecule vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of serrate RNA effector molecule vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of serrate RNA effector molecule vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 1
BLAST of serrate RNA effector molecule vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 2
BLAST of serrate RNA effector molecule vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of serrate RNA effector molecule vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 1
BLAST of serrate RNA effector molecule vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 1
BLAST of serrate RNA effector molecule vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 2
Analyses
This transcript is derived from or has results from the following analyses Cross References
External references for this transcript
Sequences
The following sequences are available for this feature:
transcript sequence >SMED30019623 ID=SMED30019623|Name=serrate RNA effector molecule|organism=Schmidtea mediterranea sexual|type=transcript|length=2740bpback to top protein sequence of SMED30019623-orf-1 >SMED30019623-orf-1 ID=SMED30019623-orf-1|Name=SMED30019623-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=797bp MADSEEECDTWRNRDKYPKEREEVKAKSPSPVEQRNEVRNDKRSFNSYQSback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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