notch-1

Overview
Namenotch-1 (AIX99542.1)
Smed IDSMED30019590
Length (bp)6155
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of notch-1 (SMED30019590) t-SNE clustered cells

Violin plots show distribution of expression levels for notch-1 (SMED30019590) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of notch-1 (SMED30019590) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for notch-1 (SMED30019590) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30019590

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 7

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
epidermal cellSMED30019590SMESG000056635.1 dd_Smed_v4_4586_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
whole organism asexual adult single-cell RNA-sequencing evidence
Category 4 cellSMED30019590SMESG000056635.1 dd_Smed_v4_4586_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017
whole organism asexual adult single-cell RNA-sequencing evidence
epidermisSMED30019590SMESG000056635.1 dd_Smed_v4_4586_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017
whole organism asexual adult single-cell RNA-sequencing evidence
dorsal region of the epidermisSMED30019590SMESG000056635.1 dd_Smed_v4_4586_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017
whole organism asexual adult single-cell RNA-sequencing evidence
ventral epidermisSMED30019590SMESG000056635.1 dd_Smed_v4_4586_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017
whole organism asexual adult colorimetric in situ hybridization evidence
ventral epidermisSMED30019590SMESG000056635.1 dd_Smed_v4_4586_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017
whole organism asexual adult single-cell RNA-sequencing evidence
dorsal region of the whole animalSMED30019590SMESG000056635.1 dd_Smed_v4_4586_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017
whole organism asexual adult colorimetric in situ hybridization evidence
Note: Hover over icons to view figure legend
Homology
BLAST of notch-1 vs. Ensembl Human
Match: SNED1 (sushi, nidogen and EGF like domains 1 [Source:HGNC Symbol;Acc:HGNC:24696])

HSP 1 Score: 112.849 bits (281), Expect = 4.688e-24
Identity = 122/404 (30.20%), Postives = 161/404 (39.85%), Query Frame = 1
Query: 2071 RACQENVKKCPKNYCQNKGRC-YNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCPL-DFCL-----NNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI-----------------------------------------CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKP--CPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXX--XXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCT-NKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            R C  +V +C    CQN G C + IN  +  C      F G  C+  +  CD   C++G  CQ+   + +C C   G+TG  CE  +  C    C N G C+   G   C C +  ++G  CET   P+ D CL     N G C+    +Q   C C   GF G  C + +     C   G CL   ++ +C C  GF G  CE  I                                         C  D C NGG C   D S  C C + F GK CEK +P  C  G C  GG C+   G   C+C    + G+     KP  C    C NGG C      + C+C    ++G  C      C  + C NGG CE     F C+C   GY G +C  +VD
Sbjct:  306 RRCHLDVNECASQPCQNGGTCTHGINSFRCQC---PAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQ-AGYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEP-FKGLRCETGDHPVPDACLSAPCHNGGTCV--DADQGYVCEC-PEGFMGLDCRERVPDDCECRNGGRCL-GANTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPY-RFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCP-PGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQ-AGYMGRRCQAEVD 697          

HSP 2 Score: 80.8777 bits (198), Expect = 2.478e-14
Identity = 92/362 (25.41%), Postives = 135/362 (37.29%), Query Frame = 1
Query: 2098 CPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPS-CDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCEISR---CFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCP--LDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNK-----PICPQNYCTKNGNCLVRDDSAVCYCDEGFT-------------GDKCEKPIC------SKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKV-GCPDNYCKNGGACEIHRGKFGCNCSLTGYG 3087
            C  + C N G C + ++    C+C +  F+G+ C+  RP  C   PC+NG  C+  G    C+C    FTG  CEI +   C +  C N G C    G  +CDC    + G+ CE    P     C+N G C     +   +C     G+ G RC       P     + T   N       A+  CD G++             G   E P C          C++GG C        C+C+  ++G  CE          L   +CR                              C NGG C  +   ++C C    + G  C  +V  C  + C++GG CE   G + C C  + +G
Sbjct:  545 CDSDPCFNGGSC-DAHDDSYTCECPRG-FHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCP-YRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPG-FSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHC---QAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCE----------LERDECRA---------------------------HPCRNGGSCRNLPGAYVCRCP-AGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESFFG 861          

HSP 3 Score: 75.485 bits (184), Expect = 1.285e-12
Identity = 75/243 (30.86%), Postives = 106/243 (43.62%), Query Frame = 1
Query: 2443 LDFCLNNGHCLLNQVNQLPYCVCNS-TGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCE--KPICSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKP-KPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXX-----XXYCENGGICSIINNVFICNCSNVSYTGERCTNKVGCPDN-YCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVDGVMCDYK 3135
            L  CLN G C+ + V   P   C+  +GF G RC+  +  C    C   G C    +S  C C  GF G  CE  +  C   +C +GG+C V + S  CVC   + G +CE     C    CL GG C  + G   C C +  + G +CE              C NGG C   +  ++C C    + G  C  +V  PD+  C+NGG C       G N +L      QC     G++C+++
Sbjct:  275 LRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEP-FKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGYVCECPE-GFMGLDCRERV--PDDCECRNGGRC------LGANTTLC-----QCPLGFFGLLCEFE 502          

HSP 4 Score: 69.707 bits (169), Expect = 7.005e-11
Identity = 90/349 (25.79%), Postives = 126/349 (36.10%), Query Frame = 1
Query: 2113 CQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPC-------KNGICQIVGNNRICNCTGTGFTGFDCEISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPK---CPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCN--KP-ICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCE--KPICSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            C+N GRC   N T   C      F+G  C+ +  +    PC         G C   G + +C C  T         S C +  C N G C        C+C +  + G+ CE  +   C    C N G C   +     +C C    F G  C   KP  C    C   G C        C C  GF+G  CE     C +  C+NGG C   D   FC C   + G+ C+    C       G    + +   R N T+   +              C+ G   S  + + +C    V     +C     C    C +GG+C+     + C CS TGY G  C+ + D
Sbjct:  474 CRNGGRCLGANTTLCQC---PLGFFGLLCEFEITA---MPCNMNTQCPDGGYCMEHGGSYLCVCH-TDHNASHSLPSPCDSDPCFNGGSCDAHDDSYTCECPRG-FHGKHCEKARPHLCSSGPCRNGGTC--KEAGGEYHCSCPYR-FTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDC-------GPPEEVKHATLRFNGTRLGAVALYA----------CDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCS-TGYEGAHCELERD 793          

HSP 5 Score: 68.1662 bits (165), Expect = 1.757e-10
Identity = 80/286 (27.97%), Postives = 110/286 (38.46%), Query Frame = 1
Query: 2095 KCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCEIS-------RCFNHKCQNNGICILKQGIPECDCTKTVY----------EGQLCETPKCPLDF-------CLNNGHCLLNQVNQLPYCVCNSTGFYGYRCN--KPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEK-PKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMG 2862
             C    C N G C++    K  CDC    F G  C+I    C  +PC NG  C+    +  C+C   G+ G  C+            +   + NG  +    +  CD   ++            G   E P+C L+        CL+ G C       L  C+C STG+ G  C   +  C  + C   G+C     + VC C  GF G  CE  +  C    C +GG+C     +  CVC + F G  CE    PC    C   G C   NG   C C +  Y G
Sbjct:  622 SCASGPCHNGGTCFHYI-GKYKCDCPPG-FSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQ-AGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQC-LEIDECRSQPCLHGGSCQDRVAGYL--CLC-STGYEGAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTC-KVGYTG 899          

HSP 6 Score: 56.9954 bits (136), Expect = 4.583e-7
Identity = 52/155 (33.55%), Postives = 66/155 (42.58%), Query Frame = 1
Query: 2218 CDPNPC-KNGICQIVGNNRICNCTGTGFTGFDCEISR--CFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCN--KPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI 2661
            C   PC   G CQ      +C C+ TG+ G  CE+ R  C  H C+N G C    G   C C    + G  CET    C    C + G C       L  CVC  + F+GY C      C  + C   G CL  + S  C C  G+TG+ C K +
Sbjct:  757 CRSQPCLHGGSCQDRVAGYLCLCS-TGYEGAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAG-FVGVHCETEVDACDSSPCQHGGRCESGGGAYL--CVCPES-FFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKEL 906          
BLAST of notch-1 vs. Ensembl Human
Match: SNED1 (sushi, nidogen and EGF like domains 1 [Source:HGNC Symbol;Acc:HGNC:24696])

HSP 1 Score: 112.464 bits (280), Expect = 6.435e-24
Identity = 122/404 (30.20%), Postives = 161/404 (39.85%), Query Frame = 1
Query: 2071 RACQENVKKCPKNYCQNKGRC-YNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCPL-DFCL-----NNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI-----------------------------------------CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKP--CPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXX--XXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCT-NKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            R C  +V +C    CQN G C + IN  +  C      F G  C+  +  CD   C++G  CQ+   + +C C   G+TG  CE  +  C    C N G C+   G   C C +  ++G  CET   P+ D CL     N G C+    +Q   C C   GF G  C + +     C   G CL   ++ +C C  GF G  CE  I                                         C  D C NGG C   D S  C C + F GK CEK +P  C  G C  GG C+   G   C+C    + G+     KP  C    C NGG C      + C+C    ++G  C      C  + C NGG CE     F C+C   GY G +C  +VD
Sbjct:  306 RRCHLDVNECASQPCQNGGTCTHGINSFRCQC---PAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQ-AGYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEP-FKGLRCETGDHPVPDACLSAPCHNGGTCV--DADQGYVCEC-PEGFMGLDCRERVPDDCECRNGGRCL-GANTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPY-RFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCP-PGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQ-AGYMGRRCQAEVD 697          

HSP 2 Score: 80.4925 bits (197), Expect = 3.382e-14
Identity = 92/362 (25.41%), Postives = 135/362 (37.29%), Query Frame = 1
Query: 2098 CPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPS-CDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCEISR---CFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCP--LDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNK-----PICPQNYCTKNGNCLVRDDSAVCYCDEGFT-------------GDKCEKPIC------SKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKV-GCPDNYCKNGGACEIHRGKFGCNCSLTGYG 3087
            C  + C N G C + ++    C+C +  F+G+ C+  RP  C   PC+NG  C+  G    C+C    FTG  CEI +   C +  C N G C    G  +CDC    + G+ CE    P     C+N G C     +   +C     G+ G RC       P     + T   N       A+  CD G++             G   E P C          C++GG C        C+C+  ++G  CE          L   +CR                              C NGG C  +   ++C C    + G  C  +V  C  + C++GG CE   G + C C  + +G
Sbjct:  545 CDSDPCFNGGSC-DAHDDSYTCECPRG-FHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCP-YRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPG-FSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHC---QAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCE----------LERDECRA---------------------------HPCRNGGSCRNLPGAYVCRCP-AGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESFFG 861          

HSP 3 Score: 75.485 bits (184), Expect = 1.305e-12
Identity = 75/243 (30.86%), Postives = 106/243 (43.62%), Query Frame = 1
Query: 2443 LDFCLNNGHCLLNQVNQLPYCVCNS-TGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCE--KPICSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKP-KPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXX-----XXYCENGGICSIINNVFICNCSNVSYTGERCTNKVGCPDN-YCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVDGVMCDYK 3135
            L  CLN G C+ + V   P   C+  +GF G RC+  +  C    C   G C    +S  C C  GF G  CE  +  C   +C +GG+C V + S  CVC   + G +CE     C    CL GG C  + G   C C +  + G +CE              C NGG C   +  ++C C    + G  C  +V  PD+  C+NGG C       G N +L      QC     G++C+++
Sbjct:  275 LRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEP-FKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGYVCECPE-GFMGLDCRERV--PDDCECRNGGRC------LGANTTLC-----QCPLGFFGLLCEFE 502          

HSP 4 Score: 68.9366 bits (167), Expect = 1.039e-10
Identity = 90/349 (25.79%), Postives = 126/349 (36.10%), Query Frame = 1
Query: 2113 CQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPC-------KNGICQIVGNNRICNCTGTGFTGFDCEISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPK---CPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCN--KP-ICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCE--KPICSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            C+N GRC   N T   C      F+G  C+ +  +    PC         G C   G + +C C  T         S C +  C N G C        C+C +  + G+ CE  +   C    C N G C   +     +C C    F G  C   KP  C    C   G C        C C  GF+G  CE     C +  C+NGG C   D   FC C   + G+ C+    C       G    + +   R N T+   +              C+ G   S  + + +C    V     +C     C    C +GG+C+     + C CS TGY G  C+ + D
Sbjct:  474 CRNGGRCLGANTTLCQC---PLGFFGLLCEFEITA---MPCNMNTQCPDGGYCMEHGGSYLCVCH-TDHNASHSLPSPCDSDPCFNGGSCDAHDDSYTCECPRG-FHGKHCEKARPHLCSSGPCRNGGTC--KEAGGEYHCSCPYR-FTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDC-------GPPEEVKHATLRFNGTRLGAVALYA----------CDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCS-TGYEGAHCELERD 793          

HSP 5 Score: 67.781 bits (164), Expect = 2.294e-10
Identity = 80/286 (27.97%), Postives = 110/286 (38.46%), Query Frame = 1
Query: 2095 KCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCEIS-------RCFNHKCQNNGICILKQGIPECDCTKTVY----------EGQLCETPKCPLDF-------CLNNGHCLLNQVNQLPYCVCNSTGFYGYRCN--KPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEK-PKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMG 2862
             C    C N G C++    K  CDC    F G  C+I    C  +PC NG  C+    +  C+C   G+ G  C+            +   + NG  +    +  CD   ++            G   E P+C L+        CL+ G C       L  C+C STG+ G  C   +  C  + C   G+C     + VC C  GF G  CE  +  C    C +GG+C     +  CVC + F G  CE    PC    C   G C   NG   C C +  Y G
Sbjct:  622 SCASGPCHNGGTCFHYI-GKYKCDCPPG-FSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQ-AGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQC-LEIDECRSQPCLHGGSCQDRVAGYL--CLC-STGYEGAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTC-KVGYTG 899          

HSP 6 Score: 56.9954 bits (136), Expect = 5.008e-7
Identity = 52/155 (33.55%), Postives = 66/155 (42.58%), Query Frame = 1
Query: 2218 CDPNPC-KNGICQIVGNNRICNCTGTGFTGFDCEISR--CFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCN--KPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI 2661
            C   PC   G CQ      +C C+ TG+ G  CE+ R  C  H C+N G C    G   C C    + G  CET    C    C + G C       L  CVC  + F+GY C      C  + C   G CL  + S  C C  G+TG+ C K +
Sbjct:  757 CRSQPCLHGGSCQDRVAGYLCLCS-TGYEGAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAG-FVGVHCETEVDACDSSPCQHGGRCESGGGAYL--CVCPES-FFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKEL 906          
BLAST of notch-1 vs. Ensembl Human
Match: SNED1 (sushi, nidogen and EGF like domains 1 [Source:HGNC Symbol;Acc:HGNC:24696])

HSP 1 Score: 112.464 bits (280), Expect = 7.239e-24
Identity = 122/404 (30.20%), Postives = 161/404 (39.85%), Query Frame = 1
Query: 2071 RACQENVKKCPKNYCQNKGRC-YNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCPL-DFCL-----NNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI-----------------------------------------CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKP--CPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXX--XXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCT-NKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            R C  +V +C    CQN G C + IN  +  C      F G  C+  +  CD   C++G  CQ+   + +C C   G+TG  CE  +  C    C N G C+   G   C C +  ++G  CET   P+ D CL     N G C+    +Q   C C   GF G  C + +     C   G CL   ++ +C C  GF G  CE  I                                         C  D C NGG C   D S  C C + F GK CEK +P  C  G C  GG C+   G   C+C    + G+     KP  C    C NGG C      + C+C    ++G  C      C  + C NGG CE     F C+C   GY G +C  +VD
Sbjct:  306 RRCHLDVNECASQPCQNGGTCTHGINSFRCQC---PAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQ-AGYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEP-FKGLRCETGDHPVPDACLSAPCHNGGTCV--DADQGYVCEC-PEGFMGLDCRERVPDDCECRNGGRCLGA-NTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPY-RFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCP-PGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQ-AGYMGRRCQAEVD 697          

HSP 2 Score: 80.4925 bits (197), Expect = 3.641e-14
Identity = 92/362 (25.41%), Postives = 135/362 (37.29%), Query Frame = 1
Query: 2098 CPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPS-CDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCEISR---CFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCP--LDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNK-----PICPQNYCTKNGNCLVRDDSAVCYCDEGFT-------------GDKCEKPIC------SKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKV-GCPDNYCKNGGACEIHRGKFGCNCSLTGYG 3087
            C  + C N G C + ++    C+C +  F+G+ C+  RP  C   PC+NG  C+  G    C+C    FTG  CEI +   C +  C N G C    G  +CDC    + G+ CE    P     C+N G C     +   +C     G+ G RC       P     + T   N       A+  CD G++             G   E P C          C++GG C        C+C+  ++G  CE          L   +CR                              C NGG C  +   ++C C    + G  C  +V  C  + C++GG CE   G + C C  + +G
Sbjct:  545 CDSDPCFNGGSC-DAHDDSYTCECPRG-FHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCP-YRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPG-FSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHC---QAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCE----------LERDECRA---------------------------HPCRNGGSCRNLPGAYVCRCP-AGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESFFG 861          

HSP 3 Score: 75.0998 bits (183), Expect = 1.391e-12
Identity = 75/243 (30.86%), Postives = 106/243 (43.62%), Query Frame = 1
Query: 2443 LDFCLNNGHCLLNQVNQLPYCVCNS-TGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCE--KPICSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKP-KPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXX-----XXYCENGGICSIINNVFICNCSNVSYTGERCTNKVGCPDN-YCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVDGVMCDYK 3135
            L  CLN G C+ + V   P   C+  +GF G RC+  +  C    C   G C    +S  C C  GF G  CE  +  C   +C +GG+C V + S  CVC   + G +CE     C    CL GG C  + G   C C +  + G +CE              C NGG C   +  ++C C    + G  C  +V  PD+  C+NGG C       G N +L      QC     G++C+++
Sbjct:  275 LRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEP-FKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGYVCECPE-GFMGLDCRERV--PDDCECRNGGRC------LGANTTLC-----QCPLGFFGLLCEFE 502          

HSP 4 Score: 68.9366 bits (167), Expect = 1.078e-10
Identity = 90/349 (25.79%), Postives = 126/349 (36.10%), Query Frame = 1
Query: 2113 CQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPC-------KNGICQIVGNNRICNCTGTGFTGFDCEISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPK---CPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCN--KP-ICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCE--KPICSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            C+N GRC   N T   C      F+G  C+ +  +    PC         G C   G + +C C  T         S C +  C N G C        C+C +  + G+ CE  +   C    C N G C   +     +C C    F G  C   KP  C    C   G C        C C  GF+G  CE     C +  C+NGG C   D   FC C   + G+ C+    C       G    + +   R N T+   +              C+ G   S  + + +C    V     +C     C    C +GG+C+     + C CS TGY G  C+ + D
Sbjct:  474 CRNGGRCLGANTTLCQC---PLGFFGLLCEFEITA---MPCNMNTQCPDGGYCMEHGGSYLCVCH-TDHNASHSLPSPCDSDPCFNGGSCDAHDDSYTCECPRG-FHGKHCEKARPHLCSSGPCRNGGTC--KEAGGEYHCSCPYR-FTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDC-------GPPEEVKHATLRFNGTRLGAVALYA----------CDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCS-TGYEGAHCELERD 793          

HSP 5 Score: 67.781 bits (164), Expect = 2.701e-10
Identity = 80/286 (27.97%), Postives = 110/286 (38.46%), Query Frame = 1
Query: 2095 KCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCEIS-------RCFNHKCQNNGICILKQGIPECDCTKTVY----------EGQLCETPKCPLDF-------CLNNGHCLLNQVNQLPYCVCNSTGFYGYRCN--KPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEK-PKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMG 2862
             C    C N G C++    K  CDC    F G  C+I    C  +PC NG  C+    +  C+C   G+ G  C+            +   + NG  +    +  CD   ++            G   E P+C L+        CL+ G C       L  C+C STG+ G  C   +  C  + C   G+C     + VC C  GF G  CE  +  C    C +GG+C     +  CVC + F G  CE    PC    C   G C   NG   C C +  Y G
Sbjct:  622 SCASGPCHNGGTCFHYI-GKYKCDCPPG-FSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQ-AGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQC-LEIDECRSQPCLHGGSCQDRVAGYL--CLC-STGYEGAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTC-KVGYTG 899          

HSP 6 Score: 56.9954 bits (136), Expect = 5.450e-7
Identity = 52/155 (33.55%), Postives = 66/155 (42.58%), Query Frame = 1
Query: 2218 CDPNPC-KNGICQIVGNNRICNCTGTGFTGFDCEISR--CFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCN--KPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI 2661
            C   PC   G CQ      +C C+ TG+ G  CE+ R  C  H C+N G C    G   C C    + G  CET    C    C + G C       L  CVC  + F+GY C      C  + C   G CL  + S  C C  G+TG+ C K +
Sbjct:  757 CRSQPCLHGGSCQDRVAGYLCLCS-TGYEGAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAG-FVGVHCETEVDACDSSPCQHGGRCESGGGAYL--CVCPES-FFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKEL 906          
BLAST of notch-1 vs. Ensembl Human
Match: NOTCH3 (notch receptor 3 [Source:HGNC Symbol;Acc:HGNC:7883])

HSP 1 Score: 112.464 bits (280), Expect = 8.559e-24
Identity = 110/402 (27.36%), Postives = 164/402 (40.80%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICI--LKQGIPECDCTKTVYEGQL----CETPKCPLDFC---LNNGHCLLNQVNQLPYC-----VCNST----------GFYGYRCN------KPIC--PQNYCT----KNGNCLVRDDSAVCYCDEGFTGDKCEKPI----CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRMVNG-MPRCNCTQTNYMGXXXXXXXXXXX--XYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVDGVMCDYKEPG 3144
            CQ +V +C    C+N  +C +       C C +  F G  CD     C P+PC +G C     +  C C   G+TG  CE  +  C +  C++ G C+  + + +  C    T    ++    C +  C    C   +N   C+       P C      C S+          G  G+RC        P+C  P + C      +G C        C C+ G++G +C + +    C    C  GG C        C C    QG+ CE   PC    C +GG+C    G +P C+C Q  + G +C++          C   GIC+ +   F C C    YTG  C   +  C  N C NGG+C+   G F C+C L G+ G +C + VD  + +   PG
Sbjct:  504 CQLDVDECASTPCRNGAKCVD-QPDGYECRCAEG-FEGTLCDRNVDDCSPDPCHHGRCVDGIASFSCAC-APGYTGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQ-GWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHG-GYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSC-LPGFAGPRCARDVDECLSNPCGPG 899          

HSP 2 Score: 98.9821 bits (245), Expect = 1.067e-19
Identity = 108/401 (26.93%), Postives = 154/401 (38.40%), Query Frame = 1
Query: 2071 RACQENVKKCPKNY-CQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKN-GICQIVGN-NRICNCTGTGFTGFDCEIS--RCFNHKCQNNGICILKQGIPECDCTKTVYEGQLC--ETPKCPL--DFCLNNGHCLLNQVNQLPYCVCNSTG---------------FYGYRCNKPI---------------------CPQNYCTKNGNCLVR--DDSAVCYCDEGFTGDKCEKPI--CS--KDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKP-KPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            R+C+ +V +C     C++ G C N       C C    + G  C+     C P+PC+N G C+  G+    C C   GF G +CE++   C  H+C N G C+       C C    + GQ C  +  +C L  + C N G C          CV   TG               F+G  C+  +                     C  N C ++  C     +  A+C C  GFTG  C++ +  CS   + C + G+CV    S  C C + + G  CE     C  G C     C    G   C C              +C    C NGG+C    N F C C +  ++G  C   V  C    C+NG  C      + C C+  G+ G  CD+ VD
Sbjct:  153 RSCRSDVDECRVGEPCRHGGTCLN-TPGSFRCQCP-AGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACL-PGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPE-WTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPS-GFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCA-EGFEGTLCDRNVD 547          

HSP 3 Score: 94.7449 bits (234), Expect = 2.043e-18
Identity = 104/361 (28.81%), Postives = 139/361 (38.50%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFC--DIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCE-TPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI----CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCE-KPKPCPVGYCLYGGKCR-MVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKV-GCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            C+ NV  CP + C N G C +   T   C C   ++ G+FC  D+      PN C NG  C        C C   G+TG  C   I  C    C +   C  +     C C      G LC     C  + C  +  C  N VN    C C   GF G  C++ +       N C   G C+    S +C C  G+TG +CE  +  C    C N   C+       C+C   F G  CE     C    C+ GG C+  VNG   C C              +C    C NG  C    + + C C+   + G  C   V  C  + C + G C      F C C+  GY G +C+ +VD
Sbjct:  233 CEVNVDDCPGHRCLNGGTCVDGVNT-YNCQCPP-EWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCV-NGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMG-KTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTC-PPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGF-SCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAE-GFEGTLCDRNVDDCSPDPCHH-GRCVDGIASFSCACA-PGYTGTRCESQVD 584          

HSP 4 Score: 90.8929 bits (224), Expect = 2.612e-17
Identity = 99/373 (26.54%), Postives = 146/373 (39.14%), Query Frame = 1
Query: 2074 ACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLC--ETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCE-KPICSKDK-----------CINGGKCVVVDRSPFCVCAKDFQGKSCEKP-KPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVGCPDN-------YCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            +C +++  C  N C N G C +      +C C    F G  C      C  NPC  G C     +  C C   G+ GF CE  +  C    C N G C+       C C +  Y G  C  E   C    CL+ G C  +  +    C C  + F G +C   +  C +  C   G C+     A C C  G++G  C+ + +  ++            C  GG+CV  D S +CVC +   G  CE+   PC    C +GG CR   G   C C          +   +C  + C++GG C  +   ++C+C   +       N+  C           C + G C    G F C C   GY G +C+  ++
Sbjct:  845 SCDQDINDCDPNPCLNGGSCQD-GVGSFSCSCLPG-FAGPRCARDVDECLSNPCGPGTCTDHVASFTCTCP-PGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLC-RPGYTGAHCQHEADPCLSRPCLHGGVC--SAAHPGFRCTCLES-FTGPQCQTLVDWCSRQPCQNGGRCV--QTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCP-PGYTGLRCEADIN 1207          

HSP 5 Score: 90.1225 bits (222), Expect = 4.867e-17
Identity = 108/394 (27.41%), Postives = 140/394 (35.53%), Query Frame = 1
Query: 2113 CQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCK-NGICQ---IVGNNRI-CNCTGTGFTGFDCEI------------SRC-----------------------------FNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCPL--DFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRC--NKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI----CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKP-KPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSI--INNVFICNCSNVSYTGERCTNKV---GCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            C N GRC  +   + AC C    + GE C ++ P C   PC   G+CQ   + G  R  C C   GF G DC +            +RC                                 C++ G C+   G   C C    Y G LCE P  P     C N G C   Q   L Y      GF G  C  N   CP + C   G C+   ++  C C   +TG  C + +       + C NGG C        CVC   + G+SC +    C    C +G  C        C C      G  C     C    C    IC    +N   IC C    +TG  C   V       N C++ G C   +G F C C   GY G +C+  V+
Sbjct:   49 CANGGRCTQLPSREAACLCPPG-WVGERCQLEDP-CHSGPCAGRGVCQSSVVAGTARFSCRCP-RGFRGPDCSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAG-YTGPLCENPAVPCAPSPCRNGGTC--RQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGK-TGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPP-GFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCG-RGYTGPRCETDVN 433          

HSP 6 Score: 87.8113 bits (216), Expect = 2.426e-16
Identity = 103/377 (27.32%), Postives = 140/377 (37.14%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEF-CDIKRPSCDPNPCKNGICQIVGNNRICNCTGTGFTGFDC--EISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCET--PKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICP------------QNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKP-KPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXX--------XXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVGCPDNYCKNGGACEIHR--------GKFGCNCSLTGYGGEQC 3099
            C  +V +C  N C   G C + +     C C     YG F C+   P C P+ C NG   + G N        G+TG  C  E   C +  C + G+C        C C ++ + G  C+T    C    C N G C    V    YC+C   G+ G  C+    P            +  C   G C+  D S  C C EG TG  CE+ +  C    C +GG C        C C   + G +CE     C    C +GG C  +     C+C     +G  CE  +              C + G C  +   F C C    YTG RC   +    N C++G     H         G F C C   G+ G +C
Sbjct:  884 CARDVDECLSNPC-GPGTCTD-HVASFTCTCPPG--YGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLES-FTGPQCQTLVDWCSRQPCQNGGRC----VQTGAYCLC-PPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGT-LGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPP-GYTGLRCEADI----NECRSGACHAAHTRDCLQDPGGGFRCLCH-AGFSGPRC 1243          

HSP 7 Score: 68.1662 bits (165), Expect = 1.946e-10
Identity = 87/334 (26.05%), Postives = 121/334 (36.23%), Query Frame = 1
Query: 2059 SLFCRACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCET------PKCPLDF---CLNNGHCL----------------------LNQVN-------------QLP----YCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSA-----VCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCE---------KPKPCPVGYCLYGGKCRMVNGMP--RCNCTQ 2847
            SL CR     +    +  CQ  G+C +  ++   C C + +  G  C+ +   C   PC++G  C+      +C C   G+ G +CE  +  C +  CQ+ G CI       C C      G LCE       P  PLD    CL+NG C+                      +N+               Q P     C+C++ GF G RC   +  C    C   G C             C+C + F G +CE+    C + +C  G  C    R P C C     G SC              C    CL+GG CR     P  RC C Q
Sbjct: 1037 SLPCREAAAQIGVRLEQLCQAGGQCVD-EDSSHYCVCPEGR-TGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECL-PGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGTL-GVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHA-GFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQ 1365          

HSP 8 Score: 68.1662 bits (165), Expect = 2.082e-10
Identity = 106/395 (26.84%), Postives = 142/395 (35.95%), Query Frame = 1
Query: 2056 ESLFCRACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGI-----CQIVG------NNRICNCTGTGFTGFDC--EISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCE--TPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCN---------KPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKC--INGGKCVVVDRSPF-CVCAKDFQGKSCEKP-KPCPVGYCLYGGKCRMVNG-----MPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVGCPDNY---------CKNGGACEIHRGK--FGCNCSLTGYGGEQCD 3102
            ES     CQ  V  C +  CQN GRC    +T   C C    + G  CDI+   C     + G+     CQ  G      ++  C C   G TG  C  E+  C    CQ+ G C    G   C+C    Y G  CE    +C    C + G C+      L  C     G  G  C           P+     C  NG C+       C C  G+TG +CE  I  C    C   +   C+      F C+C   F G  C+    PC    C +GG+CR   G        C+C Q  +  +     + C E  C  G  C        C C     +G  C +  G P            C +GG+C        F C C+  G+ G +C+
Sbjct:  990 ESFTGPQCQTLVDWCSRQPCQNGGRCV---QTGAYCLCPPG-WSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCP-EGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPG-YNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSC---PPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGPRCACPP-GLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACA-QGWTGPRCE 1373          
BLAST of notch-1 vs. Ensembl Human
Match: NOTCH1 (notch receptor 1 [Source:HGNC Symbol;Acc:HGNC:7881])

HSP 1 Score: 108.997 bits (271), Expect = 9.479e-23
Identity = 106/369 (28.73%), Postives = 159/369 (43.09%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINE-TKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGI-CQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRC--NKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEK-PKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMG-----------XXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            C+  +  C  + C+N G C    +    +C C  T + G+ C++    C  +PC++G  CQ       C+C   G++G +CE  I  C  + C N G C        CDC    + G  CE    +C  D C N  +C  + V+    C C   GF G  C  N P C ++ C   G C+   +S  C C  GFTG  C+  +  C    C++GG C     S  C C + + G +C+     C    C  GGKC   +   RC C  + + G              ++      + C++GG+C    N   C C    YTG  C + V  C  + C+NG  C  + G + C C + GY G  C +++D
Sbjct:  826 CEVVLAPCAPSPCRNGGECRQSEDYESFSCVCP-TGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQ-AGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPG-FRGTFCEEDINECASDPCRNGANCT-DCVDSY-TCTC-PAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECP-SGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRC-QAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKC-VAGYHGVNCSEEID 1185          

HSP 2 Score: 104.375 bits (259), Expect = 2.220e-21
Identity = 114/368 (30.98%), Postives = 155/368 (42.12%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKN-GICQIVGNNRICNCT-GTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCET--PKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEK--PICSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKP-KPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERC-TNKVGCP----------DNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            CQ N+ +C  N C N+G C + +     C+C    + G  C++    C P+PC+N G C+   +    +C   TG+ G  CE  I+ C    C++   C    G   C C +  Y G+ CET    C  + C N G C  + +N   +C C   GF G  C + I  C  + C    NC    DS  C C  GF+G  CE   P C++  C NGG CV    S  C+C   F G  C+     C    CL+GG C+   G  RC C Q             C    C+NGG C   +  + C C +  +TG  C    V C              C++GG C        C C   GY G  C+  VD
Sbjct:  788 CQTNINECASNPCLNQGTCID-DVAGYKCNCL-LPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHC-QAGYSGRNCETDIDDCRPNPCHNGGSC-TDGINTA-FCDC-LPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPS-GWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQ-AGYTGSYCEDLVD 1147          

HSP 3 Score: 89.7373 bits (221), Expect = 6.168e-17
Identity = 95/308 (30.84%), Postives = 133/308 (43.18%), Query Frame = 1
Query: 2242 GICQIVGNNRICNCTGTGFTGFDCE-ISRCFNHKCQNNGIC--ILKQGIPECDCTKTV-YEGQLCETP---KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKP-ICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDK--CINGGKCVVVDRSPFCVCAKDFQGKSCEKPK-PCPVGYCLYGGKCRMVNGMPR-CNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG---CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            G C+       C C G  F G  C+  + C +  C+N G C  + ++G+ +  C+  + + G LC TP    C  + C N G C L  + +   C C   G+ G  C +   C  N C   G CL  + S +C+C   F G  C + +  C +    C +GG C     S  CVC     G +CE+P  PC    C  GG CR    +   C C          E    CP   C+NGG C    N + C C    +TG+ CT  V       N C+NGG C    G + C C + G+ GE C + +D
Sbjct:   35 GKCEAANGTEACVCGGA-FVGPRCQDPNPCLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEY-KCRC-PPGWSGKSCQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCP-PEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVC-VNGWTGEDCSENID 337          

HSP 4 Score: 83.1889 bits (204), Expect = 5.490e-15
Identity = 107/353 (30.31%), Postives = 147/353 (41.64%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYN-INETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGI-CQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCT-KTVYEGQLCET--PKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSC-EKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERC-TNKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCD 3102
            C+ N  +C  + C + GRC + INE +  C    T F G  C      C   PCKNG  C    N   C CT  G+TG  CE  I  C    C + G C  K G+    C  +  Y G  CET   +C    C + G C       L +C+  +TG      N   C  + C  +G CL + D   C C+ G+TG  C   I  C+ + C NGG C        C C + +   +C  +   C    C++G     +NG  +C+C              +C    C NGG C  + + ++C C    ++G  C TN   C  N C N G C      + CNC L  Y G  C+
Sbjct:  487 CEVNTDECASSPCLHNGRCLDKINEFQCEC---PTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCT-EGYTGTHCEVDIDECDPDPC-HYGSC--KDGVATFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTG-PNCEINLDDCASSPC-DSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGY-KCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCRE-GFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLP-YTGATCE 827          

HSP 5 Score: 81.2629 bits (199), Expect = 2.514e-14
Identity = 101/361 (27.98%), Postives = 148/361 (41.00%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYN-INETKIACDCKKTQFYGEFC--DIKRPSCDPNPCKN-GICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCE-TPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI----CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCE-KPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXX-XXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            C+EN+  CP N C+N G C + +N     C     ++ G++C  D+      PN C+N G C        C C   G+TG DC   I  C +  C +   C  +     C+C      G LC     C  + C    +C  N VN    C C S G+ G  C++ +       N C   G C+    S  C C +G+TG +CE  +  C  + C N   C+       C+C   ++G  CE     C    CL+ G+C       +C C  T + G        +C    C+NG  C    N + C C+   YTG  C   +   D    + G+C+     F C C   GY G  C+  ++
Sbjct:  254 CEENIDDCPGNNCKNGGACVDGVNTYNCRC---PPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCV-NGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHG-RTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPS-GYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKINEFQCECP-TGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTE-GYTGTHCEVDIDECDPDPCHYGSCKDGVATFTCLCR-PGYTGHHCETNIN 605          

HSP 6 Score: 80.4925 bits (197), Expect = 4.305e-14
Identity = 84/291 (28.87%), Postives = 113/291 (38.83%), Query Frame = 1
Query: 2113 CQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDC--EISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCE-------TPKCPLDF---CLNNGHCL---------------------------------------LNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSA---VCYCDEGFTGDKCEKP--ICSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGYCLYGGKC 2808
            CQ+ G C +   T   C C+   + G +C+     C P+PC+NG  C        C C   G+ G +C  EI  C +H CQN G C+      +C C +   +G  CE        P  P+     C NNG C+                                       + +VN   +C C + G  G RC   I  C    C   G C V  ++A   +C C  GF G  CE     C   +C+NGG C+   RSP C+C   F G  C+ P   P   CL G  C
Sbjct: 1116 CQHGGLCVDAGNTH-HCRCQ-AGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCV-AGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGT-QGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDF-HCECRA-GHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQFPASSP---CLGGNPC 1397          

HSP 7 Score: 77.0258 bits (188), Expect = 4.129e-13
Identity = 109/393 (27.74%), Postives = 145/393 (36.90%), Query Frame = 1
Query: 2071 RACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGI-CQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPY-CVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPICS------------KDKCINGGKCVVVDRSPFCVCAKDFQGKSCE------KPKPCPVGYC----LYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVGCPDNY---------------CKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            R C+ ++  C  N C N G C +   T   CDC    F G FC+     C  +PC+NG  C    ++  C C   GF+G  CE     C    C N G C+       C C    + G  C+    +C    CL+ G C   Q     Y C C   G+ G  C   +  C  + C   G C        C C  G+TG  C+ P  S               C +GG CV    +  C C   + G  CE       P PC  G      L G  C+ V G    NC++            +C    C+NGG C  + N + C+C        R T  V C  N                C N G C    G + C C   G+ GE+C+  V+
Sbjct:  902 RNCETDIDDCRPNPCHNGGSCTDGINTAF-CDCLPG-FRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCP-AGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPG-FTGSYCQHDVNECDSQPCLHGGTC---QDGCGSYRCTC-PQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEE---------IDECLSHPCQNGGTCLDLPNTYKCSCP-------RGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCP-PGFVGERCEGDVN 1269          

HSP 8 Score: 76.6406 bits (187), Expect = 6.610e-13
Identity = 105/360 (29.17%), Postives = 141/360 (39.17%), Query Frame = 1
Query: 2095 KCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKN-GICQIVGNNRICNCTGTGFTGFDC--EISRCFNHK--CQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCL-LNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI----CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSC-EKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSI--INNVFICNCSNVSYTGERCTNKV---GCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
             C  N C+N G C  +  T+  C C    + G+ C    P C  NPC N G C     + IC+C  + F G  C  +++ C      C++ G C  + G   C C +  + G  CE P   C    C N G C     V     C+    GF G  C + I  CP N C   G C+   ++  C C   +TG  C + +       + C NGG C        CVC   + G+ C E    C    C +G  C        C C      G  C     C    C  G  C    +N   IC C +  YTG  C+  V       N C++ G C    G F C C L GY G +C+  V+
Sbjct:  105 ACLTNPCRNGGTCDLLTLTEYKCRCPPG-WSGKSCQQADP-CASNPCANGGQCLPFEASYICHCPPS-FHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVC-RATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACL---PGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPH-GRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPS-GYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQC-LQGYTGPRCEIDVN 454          

HSP 9 Score: 72.7886 bits (177), Expect = 7.821e-12
Identity = 106/365 (29.04%), Postives = 147/365 (40.27%), Query Frame = 1
Query: 2077 CQENVKKCPK--NYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKN-GICQIVGN-NRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLC--ETPKCPL--DFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCE-KPICSKDKCINGGKCVV--VDRSPFCVCAKDFQGKSCEKP-KPCPVGY--CLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERC-TNKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            C+++V +C +    C++ G C+N       C C+ T   G  C+     C P+PC+N G C+  G+    C C   GFTG +CE  I  C  + C+N G C+       C C    + GQ C  +  +C L  + C N G C  +  +    CVC   G+ G  C++ I  C    C     C  R  S  C C  G TG  C     C  + C  G  C    V+    C C   + G +C +    C +G   C + GKC    G   C C Q     +      +C    C+N   C      F C C    Y G  C  N   C  + C + G C     +F C C  TG+ G  C   VD
Sbjct:  175 CRQDVNECGQKPGLCRHGGTCHN-EVGSYRCVCRATH-TGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACL-PGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPE-WTGQYCTEDVDECQLMPNACQNGGTC--HNTHGGYNCVC-VNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICM-PGYEGVHCEVNTDECASSPCLHNGRCLDKINEFQCECP-TGFTGHLCQYDVD 530          

HSP 10 Score: 68.9366 bits (167), Expect = 1.362e-10
Identity = 101/381 (26.51%), Postives = 142/381 (37.27%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYN-INETKIACDCKKTQFYGEFCDIKRPSCDPNPC-KNGICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCPLD------------FCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCE------KPKPCPVGY---CLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNV--FICNCSNVSYTGERCTNKV-GCPDNYCKNGGACEI----HRGKFGCNCSLTGYGGEQCDQKV 3111
            C+ N   C ++ C N G C + IN     C      F G +C      CD  PC   G CQ    +  C C   G+TG +C+  +  C +  C+N G C        C+C  + + G  C+ P    +             C + G C+        +C C + G+ G  C   +  C  + C     C        C C  G+ G  C + I  C    C NGG C+ +  +  C C +  QG  CE       P   PV     C   G C    G   C C       +      +C    C+  G  + +  V  F C C    +TG RC + + GC    CKNGG C +     RG F C C   G+ G  C+   
Sbjct:  980 CENNTPDCTESSCFNGGTCVDGINSFTCLC---PPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCP-QGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCEC-PSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCV--DAGNTHHCRCQA-GYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCEC-RAGHTGRRCESVINGCKGKPCKNGGTCAVASNTARG-FICKCP-AGFEGATCENDA 1349          

HSP 11 Score: 65.0846 bits (157), Expect = 1.737e-9
Identity = 62/197 (31.47%), Postives = 81/197 (41.12%), Query Frame = 1
Query: 2530 GYRCNKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKP-ICSKDKCINGGKCVVVDRSPF----CVCAKDFQGKSCEKP--KPCPVGYCLYGGKCRMVNGMP-RCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERC---TNKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYG 3087
            G RC++P      C   G C   + +  C C   F G +C+ P  C    C N G C VVDR       C CA  F G  C  P    C    C  GG C ++     +C C    + GK C++   C    C NGG C      +IC+C   S+ G  C    N+ G     C++GG C    G + C C  T  G
Sbjct:   21 GPRCSQP---GETCLNGGKCEAANGTEACVCGGAFVGPRCQDPNPCLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCP-PGWSGKSCQQADPCASNPCANGGQCLPFEASYICHCP-PSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTG 212          

HSP 12 Score: 58.5362 bits (140), Expect = 1.826e-7
Identity = 48/165 (29.09%), Postives = 71/165 (43.03%), Query Frame = 1
Query: 2638 GDKCEKPICSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRMVN--GMPRCNCT-QTNYMGX--XXXXXXXXXXXYCENGGICSIIN-NVFICNCSNVSYTGERCTNKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            G +C +P    + C+NGGKC   + +  CVC   F G  C+ P PC    C   G C +V+  G+    C+    + G          C    C NGG C ++    + C C    ++G+ C     C  N C NGG C      + C+C  + + G  C Q V+
Sbjct:   21 GPRCSQP---GETCLNGGKCEAANGTEACVCGGAFVGPRCQDPNPCLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCP-PGWSGKSCQQADPCASNPCANGGQCLPFEASYICHCPPS-FHGPTCRQDVN 180          
BLAST of notch-1 vs. Ensembl Celegans
Match: crb-1 (Drosophila CRumBs homolog [Source:UniProtKB/TrEMBL;Acc:Q19350])

HSP 1 Score: 113.235 bits (282), Expect = 1.594e-24
Identity = 156/579 (26.94%), Postives = 239/579 (41.28%), Query Frame = 1
Query: 1504 IPLTNEGIILFIEFKTKFDGI--IWHAVNVFSSEDWMTLLVNSNSIILAY------SLPPNEGVHTIEMTRGGILIQDNTWHRVIINLNKPKEILYIHIDDVESLT-NEIKLKNSK---------KELAEMNFISLSLGGISDNSQYTQFYNLLRKKNPEVSKLFSGPDELKF-IGCLGDILVINSSYSGNLIQKPNVNSFPKESLFCRA------CQENVKKCPKNYCQNKGRCYN-INETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGICQIVGNNR---ICNCTGTGFTGFDCEISR---CFNHKCQNNGICILK-QGIPECDCTKTVYEGQLCETP---KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPF-CVCAKDFQGKSCEKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCT-NKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            I ++N  ++ +    TKF  +  I  ++   S    +  L    S + AY      +L  N G  TI+  +   +I D  WH++I+N   P ++L   ID V+ ++ N++    SK         +E  E+ F  L L  + +    +      + K P  S+ ++  D+     GC+         YS  L     V+ + K    C A      C++NV  C    C   G C + I+E K  C+     F+GE C++ +  C+   C NG  + V N     +C C G  + G  C +++   C +  CQN G C+ K     EC+C    Y G+LCE     +C    C N GHC++      P C C   G+ G  C K +  C  N C+  G C    ++ VC CD  + G  C+  +  C    C N G C   D + F C C K F G  CE    C    C++G   ++      C+C          +K   C    C NG  C      + C C+ V + G  C  N   C   +CKNG  C      + C C  TG+ G  C   ++
Sbjct: 1007 ITISNGSMLTYSLAPTKFMTLPSIEFSIKAHSQNGHIFTLTIDKSTLSAYLFKKRLALATNSGSGTIQ--KFDSVIADGNWHQIILN---PHKVL---IDSVKFISDNQLYPAESKSGASLFVGEQEPQEVTFACLDLFKMGEYPTLS----FTKVKIPTNSETWNLTDKASVGTGCMSTDQC--GLYSTCLNGATCVDIWNKRKCVCPAGFAGENCEDNVNDCKFVDCGKHGYCLDGIDEAKCICN---NGFHGEHCELAKDECEGVECHNGG-KCVKNRSEKIVCQC-GNSWMGDSCNVTKTTNCKDSPCQNFGQCMQKTDTFFECNCMDG-YSGELCEQRDVNECNHYDC-NRGHCVMTVSG--PACQC-EMGYTGRFCEKLLNQCSSNTCSSRGACSPVWNNTVCNCDNNWRGAHCQHQMDTCLDFPCNNDGVCRTNDENTFSCECQKFFMGTRCEIEGSCLKAQCVHGECIQLSPETHTCSCNIGYEGDACDKKIDYCKAGPCLNGANCENKLTGYKCTCA-VGFEGADCEINIDECALEFCKNGAKCRDKINDYECVCDGTGFEGRNCTTDIN 1560          

HSP 2 Score: 106.686 bits (265), Expect = 1.714e-22
Identity = 139/536 (25.93%), Postives = 199/536 (37.13%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGI-CQIVGNNRICNCTGTGFTGFDCEIS---RCFNHKCQNNGICI--------------------LKQGIPECDCTKTVYEGQL---------CETPK--------------CPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI-CPQNY--CTKNGNCLVRDDSAVCYCDEGFTGDKCE-------KPICSKDKCINGGKCVV-VDRSPFCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRMVNGMPRCNCTQT-------------------------NYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFG----CNCSLTGYGGEQCDQKVDGVMCD---YKEPGYAITAFKPPMVSSGIVTSMGFQTFVKTGTLFCYET-ADDKYWLIKLVNGRLVADINGISFN--MKTVVSDGRYHFLKVSRDETNFVISL 3402
            CQ N   C  + CQN G C   N   + C C    F G+ C+     C  N C+NG  C+ +  +  C C   GF+G  CEI    +C +  C NNG CI                    LK  + EC C    +   L         CE P               C  + CLN GHC+ +  N L  C C  + F G  C +P+ C  N   C   G C+    +  C C EGF G  CE        P CS  +C+NGG C +  +  PFCVC + F G  CE    C +  C  GG C+  +G   C+CT                              G       K   + C N   C  + +  +C C +  Y G++C  K   C    C +G  C            C C + G+ G+QC+            Y       +       +        F+T V+   L   E    +K   I+L++G LV ++ G S    +   VSD +++ + V  ++    I +
Sbjct:  122 CQSNEPSCATHTCQNNGTCVAEN-GNVKCACPPG-FVGDHCETDEDECKENFCQNGADCENLKGSYECKCL-KGFSGKYCEIQDKKQCTSDYCHNNGQCISTGSDLSCKCSPGFDGAFCELKAEVNECICENPAHVCSLVNGTSRTTQCECPSGFMGADCKELQARPCDREPCLNGGHCVDDGQN-LFTCFCLPS-FTGIYCGEPVDCLVNGSDCKNGGKCVFALAATTCQCPEGFNGSNCEISNSYRSHPTCSDIRCLNGGSCKLDAEGEPFCVCEEGFDGPFCEPKSGCTINPCQNGGTCQDADGQYFCHCTSGFGGVHCETVDEPSTPIPTLGTFPSFTTSGIDGFSQSKISCEDCVNSSNCLDVESGPVCICDD-GYFGQKCDQKHDKCSKVSCPSGQTCSQVNDNVNITAQCGCEI-GHFGQQCEMVTSATFSAKSLYIHQSSKFSLGTSSFENIAYELEFSFRTTVENTHLASSENILGEKILSIQLLSGYLVFNMTGNSLEHLLPMRVSDAQWYTVFVKGEDNKIQIEV 650          

HSP 3 Score: 96.2857 bits (238), Expect = 1.982e-19
Identity = 116/371 (31.27%), Postives = 151/371 (40.70%), Query Frame = 1
Query: 2167 CKKTQFYGEFCDIKRPSCDPNPCK-NGICQIVGNNRICNCTGTGFTGFDCEI--SRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCE---TPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRC------NKPIC--PQNYCTKNGNCLVRDDSAV--CYCDEGFTGDKC---EKPICSKDKCINGGKCVVVDRSPF-CVCAKDFQGKSCEKPKPCPV--GYCLYGGKCRMVNGMPRCNCTQ-----TNYMGXXXXXXXXXXXXYCENGGICSI-INNVFICNCSNVSYTGERCTNKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVDGVMCDYKEPGYAITAFK--PPMVSSGI 3189
            C K       C    PSC  + C+ NG C     N  C C   GF G  CE     C  + CQN   C   +G  EC C K  + G+ CE     +C  D+C NNG C+    +    C   S GF G  C      N+ IC  P + C+     LV   S    C C  GF G  C   +   C ++ C+NGG CV   ++ F C C   F G  C +P  C V    C  GGKC        C C +        +         C +  C NGG C +       C C    + G  C  K GC  N C+NGG C+   G++ C+C+ +G+GG  C + VD       EP   I      P   +SGI
Sbjct:  112 CTKGADGSYICQSNEPSCATHTCQNNGTCVAENGNVKCACP-PGFVGDHCETDEDECKENFCQNGADCENLKGSYECKCLKG-FSGKYCEIQDKKQCTSDYCHNNGQCISTGSDLSCKC---SPGFDGAFCELKAEVNECICENPAHVCS-----LVNGTSRTTQCECPSGFMGADCKELQARPCDREPCLNGGHCVDDGQNLFTCFCLPSFTGIYCGEPVDCLVNGSDCKNGGKCVFALAATTCQCPEGFNGSNCEISNSYRSHPTCSDIRCLNGGSCKLDAEGEPFCVCEE-GFDGPFCEPKSGCTINPCQNGGTCQDADGQYFCHCT-SGFGGVHC-ETVD-------EPSTPIPTLGTFPSFTTSGI 462          

HSP 4 Score: 68.1662 bits (165), Expect = 7.866e-11
Identity = 97/321 (30.22%), Postives = 130/321 (40.50%), Query Frame = 1
Query: 2215 SCDPNPCKNG-ICQIVGNNRICNCT-GTGFTGFDCEISRCFNHKCQNNGICILKQ-GIPECDCTKTVYEGQLCETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCE--KPICSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCE--KPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCEN-GGICSIIN---NVFICNCSNVSYTGERCTNKVG--CPDNYCKNGGAC-EIHRGKFGCNC--SLTG-YGGEQCDQKVDGVMC 3126
            +C  N C NG  C +    R+  C    GF+G  C+   C  H    N  C+    G   C C++  + G LC+      D           Q      C   + G Y  + N+P C  + C  NG C+  + +  C C  GF GD CE  +  C ++ C NG  C  +  S  C C K F GK CE    K C   YC   G+C        C C+   + G  CE   +  E  CEN   +CS++N       C C +  + G  C       C    C NGG C +  +  F C C  S TG Y GE  D  V+G  C
Sbjct:   21 ACSRNTCLNGGTCTVNDETRMFQCECPKGFSGLLCQ-DNCSLHCLHGN--CVKGTFGEETCQCSEG-WMGSLCDNLVTDDD----TAQKCSPQCGDDERCTKGADGSYICQSNEPSCATHTCQNNGTCVAENGNVKCACPPGFVGDHCETDEDECKENFCQNGADCENLKGSYECKCLKGFSGKYCEIQDKKQCTSDYCHNNGQCISTGSDLSCKCS-PGFDGAFCELKAEVNECICENPAHVCSLVNGTSRTTQCECPS-GFMGADCKELQARPCDREPCLNGGHCVDDGQNLFTCFCLPSFTGIYCGEPVDCLVNGSDC 331          

HSP 5 Score: 56.225 bits (134), Expect = 3.057e-7
Identity = 77/282 (27.30%), Postives = 107/282 (37.94%), Query Frame = 1
Query: 2080 QENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKN-GICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICIL-KQGIPECDCTKTVYEGQLCETPKCPLDFCLNNGHCLLNQVN-QLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKC--------VVVDRSPF-------------------------------CVCAKDFQGKSCEKPKPCPV 2781
            Q +V +C    C N+G C  +  +  AC C+   + G FC+     C  N C + G C  V NN +CNC    + G  C+  +  C +  C N+G+C    +    C+C K  + G  CE     L     +G C+  Q++ +   C CN  G+ G  C+K I  C    C    NC  +     C C  GF G  CE  I  C+ + C NG KC         V D + F                               C C   F G  C    PC  
Sbjct: 1328 QRDVNECNHYDC-NRGHCV-MTVSGPACQCE-MGYTGRFCEKLLNQCSSNTCSSRGACSPVWNNTVCNCDNN-WRGAHCQHQMDTCLDFPCNNDGVCRTNDENTFSCECQK-FFMGTRCEIEGSCLKAQCVHGECI--QLSPETHTCSCN-IGYEGDACDKKIDYCKAGPCLNGANCENKLTGYKCTCAVGFEGADCEINIDECALEFCKNGAKCRDKINDYECVCDGTGFEGRNCTTDINECANPNNCINGECTNTLGNYKCACRNGFIGPRCSVRNPCTA 1601          
BLAST of notch-1 vs. Ensembl Celegans
Match: clec-78 (C-type LECtin [Source:UniProtKB/TrEMBL;Acc:Q20531])

HSP 1 Score: 102.449 bits (254), Expect = 3.552e-21
Identity = 114/360 (31.67%), Postives = 159/360 (44.17%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYN-INETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCE--TPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRD--DSAVCYCDEGFTGDKCE--KPICSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPK-PCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNK-VGCPDNYCKNGGAC-EIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            C +N+  C  + C     C + IN+ K  C+C  T F G+ C IK   C  +PC +G+C     +R C C   G+TG +C+  I  C    CQN+  CI +     C+C    YEG  C+     C    C NN  C    +    +C C + GF G  C   I  C +N C K G    RD  +   C C  G+TG +C+  +  C+   C+N  +CV +  +  CVC   + G  CE+    C    C   G C  +     C C            P +C  + C NGG C    +   C C   S+TG+ C  K  GC    C+NGG C E   G   C CS  G+ GE+C+  +D
Sbjct: 2166 CDKNIDDCADSPCALNATCVDLINDYK--CECP-TGFSGKRCHIKENLCASSPCVHGLCIDKLYSRQCLCQ-PGWTGENCDQNIDECAASPCQNDAKCIDEINGYMCECADG-YEGVHCQHLVDHCAKQPCHNNATC--TNMGATYHCDC-TLGFDGVHCEMNIDECAENQCDKLGTESCRDAVNDFKCVCKPGYTGPRCDVKQDQCADSPCLNDAQCVDMGGAYKCVCKSGWTGPKCEQDNGSCAAKPCRNNGFCVSLVADYFCVCPPGVSGKNCESAPNRCIGQPCHNGGECGDFGSHLECACP-ASFTGKGCEFKNTGC--KTCENGGKCAEAAGGLQKCECS-PGFTGERCETNID 2513          

HSP 2 Score: 79.7221 bits (195), Expect = 2.513e-14
Identity = 97/355 (27.32%), Postives = 149/355 (41.97%), Query Frame = 1
Query: 2098 CPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKN-GICQIVGNNRICNCTGTGFTGFDC--EISRCFNHKCQNNGICILKQGIPECDCT-KTVYEGQLCE--TPKCPL-DFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKC--EKPICSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKP-KPCPVGYCLYGGKC-RMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGG--ACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            C    C+N   C ++   +  C CK   + G+ C++    C   PC N G C+ VG    C C    F G  C  E   C   KC N G+C    G+    C  +T + G  CE  T  C   + C N   C+  ++ +   C C   G+ G  C+K I  C  + C  N  C+   +   C C  GF+G +C  ++ +C+   C++ G C+    S  C+C   + G++C++    C    C    KC   +NG   C C               C ++ C N   C+ +   + C+C+ + + G  C   +  C +N C   G  +C      F C C   GY G +CD K D
Sbjct: 2017 CSAKMCENNAEC-SVFMHRAQCHCKPG-YVGDRCEMLEDVCSTQPCYNGGKCEQVGTTYKCTCPKM-FNGARCQFESDECNGVKCPNGGVCHDLPGVKSTTCLCRTGFAGPQCEEITDICSTNNPCRNGARCIGEKLGRF-KCQC-VPGWEGPNCDKNIDDCADSPCALNATCVDLINDYKCECPTGFSGKRCHIKENLCASSPCVH-GLCIDKLYSRQCLCQPGWTGENCDQNIDECAASPCQNDAKCIDEINGY-MCECADGYEGVHCQHLVDHCAKQPCHNNATCTNMGATYHCDCT-LGFDGVHCEMNIDECAENQCDKLGTESCRDAVNDFKCVCK-PGYTGPRCDVKQD 2362          

HSP 3 Score: 62.3882 bits (150), Expect = 4.747e-9
Identity = 90/356 (25.28%), Postives = 141/356 (39.61%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDP-NPCKNG---ICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPK--CPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQ 3105
            CQ    +C    C N G C+++   K      +T F G  C+     C   NPC+NG   I + +G  + C C   G+ G +C+  I  C +  C  N  C+      +C+C  T + G+ C   +  C    C+ +G C+    ++   C+C   G+ G  C++ I  C  + C  +  C+   +  +C C +G+ G  C+  +  C+K  C N   C  +  +  C C   F G  CE                     +  C   Q + +G +                 C    N F C C    YTG RC  K   C D+ C N   C    G + C C  +G+ G +C+Q
Sbjct: 2086 CQFESDECNGVKCPNGGVCHDLPGVKSTTCLCRTGFAGPQCEEITDICSTNNPCRNGARCIGEKLGRFK-CQCV-PGWEGPNCDKNIDDCADSPCALNATCVDLINDYKCEC-PTGFSGKRCHIKENLCASSPCV-HGLCIDKLYSR--QCLCQP-GWTGENCDQNIDECAASPCQNDAKCIDEINGYMCECADGYEGVHCQHLVDHCAKQPCHNNATCTNMGATYHCDCTLGFDGVHCEM-------------------NIDECAENQCDKLGTES----------------CRDAVNDFKCVC-KPGYTGPRCDVKQDQCADSPCLNDAQCVDMGGAYKCVCK-SGWTGPKCEQ 2397          
BLAST of notch-1 vs. Ensembl Celegans
Match: lin-12 (pep chromosome:WBcel235:III:9060096:9071760:-1 gene:WBGene00003001.1 transcript:R107.8.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:lin-12)

HSP 1 Score: 97.4413 bits (241), Expect = 9.035e-20
Identity = 115/376 (30.59%), Postives = 159/376 (42.29%), Query Frame = 1
Query: 2110 YCQNKGRCYNINETKIACDCKKTQFYGEFCDI--KRPSCDPNPCKNGICQIVGNNRICNCTGTGFTGFDCEISR--CFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCPL--DFCLNNGHCLLNQVNQLPY-CVCNSTGFYGYRC--NKPIC-PQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCV-VVDRSPFCVCAKDFQGKSCEKPKPCPVGY--------------------CLYGGKCRMVNGMPRC-------NCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNV--FICNCSNVSYTGERCT-NKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQK 3108
            YCQN G C   ++    C C    ++G  C++  K  SC  NPC +G+C        C C   G++G  C+  +  C N+KC+    CI       CDC      G  CE   C    D C N+G C+ + +++  + C C   G+ G  C  +K  C  +N C  NG C+    S  C C  GF G  C++P+  C    C N G C+   D SP C C   F GK CEK   CP+G+                    C  GGKC  ++G   C        C      GK       C    C N   C  ++    + C C    + G+ C  +K  C +N C NGG C  HR  F C+C   G+ G  C+Q+
Sbjct:  220 YCQNGGFC---DKASSKCQCPPG-YHGSTCELLEKEDSCASNPCSHGVCISFSGGFQCICD-DGYSGSYCQEGKDNCVNNKCEAGSKCINGVNSYFCDCPPE-RTGPYCEKMDCSAIPDIC-NHGTCIDSPLSEKAFECQC-EPGYEGILCEQDKNECLSENMCLNNGTCVNLPGSFRCDCARGFGGKWCDEPLNMCQDFHCENDGTCMHTSDHSPVCQCKNGFIGKRCEKE--CPIGFGGVRCDLRLEIGICSRQGGKCFNGGKC--LSGFCVCPPDFTGNQCEVNRKNGKSSLSENLCLSDPCMNNATCIDVDAHIGYACICKQ-GFEGDICERHKDLCLENPCSNGGVCHQHRESFSCDCP-PGFYGNGCEQE 581          

HSP 2 Score: 62.3882 bits (150), Expect = 4.613e-9
Identity = 79/274 (28.83%), Postives = 112/274 (40.88%), Query Frame = 1
Query: 2119 NKGRCYN--INETKIACDCKKTQFYGEFCDIKRPSC-DPNPC-KNGICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICI-LKQGIPECDCTKTVYEGQLCETPKCPLDF--------------------CLNNGHCLLNQVNQLPYCVCNSTGFYGYRC-----------NKPICPQNYCTKNGNCLVRDDSA--VCYCDEGFTGDKCE--KPICSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPK--PCPVGYCLYGGKC 2808
            N G C +  ++E    C C+   + G  C+  +  C   N C  NG C  +  +  C+C   GF G  C+  ++ C +  C+N+G C+      P C C K  + G+ CE  +CP+ F                    C N G CL        +CVC    F G +C           ++ +C  + C  N  C+  D      C C +GF GD CE  K +C ++ C NGG C     S  C C   F G  CE+ K   C    C  GG C
Sbjct:  335 NHGTCIDSPLSEKAFECQCEPG-YEGILCEQDKNECLSENMCLNNGTCVNLPGSFRCDCA-RGFGGKWCDEPLNMCQDFHCENDGTCMHTSDHSPVCQC-KNGFIGKRCEK-ECPIGFGGVRCDLRLEIGICSRQGGKCFNGGKCLSG------FCVC-PPDFTGNQCEVNRKNGKSSLSENLCLSDPCMNNATCIDVDAHIGYACICKQGFEGDICERHKDLCLENPCSNGGVCHQHRESFSCDCPPGFYGNGCEQEKMFRCLKSTCQNGGVC 597          

HSP 3 Score: 57.3806 bits (137), Expect = 1.460e-7
Identity = 100/353 (28.33%), Postives = 145/353 (41.08%), Query Frame = 1
Query: 2218 CDPNPCKN-GICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHK--CQNNG---------ICILKQGIPECDC-----TKTV-YEGQLC------ETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCN----KPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCE--KPICSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEK------PKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGX--XXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFG--CNCSLTGYGGEQCDQK----VDGVMCDYK 3135
            C P+ C N G C   GN   C C   GF G  CE  ++ C  +K  C N           IC+  QG    DC     T TV ++  +C      + P     +C N G C          C C   G++G  C     +  C  N C+ +G C+       C CD+G++G  C+  K  C  +KC  G KC+    S FC C  +  G  CEK      P  C  G C+      +      C C +  Y G   + +K +   E  C N G C  +   F C+C+   + G+ C   +  C D +C+N G C +H       C C   G+ G++C+++      GV CD +
Sbjct:  118 CYPSVCMNGGQCIGAGNRAKCACP-DGFKGERCELDVNECEENKNACGNRSTCMNTLGTYICVCPQGFLPPDCLKPGNTSTVEFKQPVCFLEISADHPDGRSMYCQNGGFC----DKASSKCQC-PPGYHGSTCELLEKEDSCASNPCS-HGVCISFSGGFQCICDDGYSGSYCQEGKDNCVNNKCEAGSKCINGVNSYFCDCPPERTGPYCEKMDCSAIPDICNHGTCI---DSPLSEKAFECQC-EPGYEGILCEQDKNECLSENMCLNNGTCVNLPGSFRCDCAR-GFGGKWCDEPLNMCQDFHCENDGTC-MHTSDHSPVCQCK-NGFIGKRCEKECPIGFGGVRCDLR 456          

HSP 4 Score: 55.0694 bits (131), Expect = 7.938e-7
Identity = 64/255 (25.10%), Postives = 93/255 (36.47%), Query Frame = 1
Query: 2407 YEGQLCETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICPQNY---------------CTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDK--CINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            + G+ CE  +C +  C  +  C+ ++  ++  CVC      G    KP CP  Y               C   G C+   + A C C +GF G++CE  +  C ++K  C N   C+    +  CVC + F    C KP          G    +    P C         +           YC+NGG C   ++   C       T E    +  C  N C + G C    G F C C   GY G  C +  D
Sbjct:   55 FGGEYCEQ-QCDVSKCGADEKCVFDKDYRMETCVCKDCDINGNSLLKPSCPSGYGGDDCKTQGWCYPSVCMNGGQCIGAGNRAKCACPDGFKGERCELDVNECEENKNACGNRSTCMNTLGTYICVCPQGFLPPDCLKP----------GNTSTVEFKQPVC-------FLEISADHPDGRSMYCQNGGFCDKASSKCQCPPGYHGSTCELLEKEDSCASNPCSH-GVCISFSGGFQCICD-DGYSGSYCQEGKD 289          
BLAST of notch-1 vs. Ensembl Celegans
Match: slt-1 (Slit homolog 1 protein [Source:UniProtKB/Swiss-Prot;Acc:G5EFX6])

HSP 1 Score: 95.9005 bits (237), Expect = 3.028e-19
Identity = 124/466 (26.61%), Postives = 181/466 (38.84%), Query Frame = 1
Query: 2506 VCNST-GFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAV-CYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCE-KPKPC--PVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCS-NVSYTGERC----------TNKVGCPDNYCKNGG-ACEIHRGKFGCNCSLTGYGGEQCDQKVDGVMCDYKEPGYAITAFKPPMVSSGIVTSMGFQTFVKTGTLFCYETADDKYWLIKLVNGRL-----VADINGISFNMKTVVSDGRYHFLKVSRDETNFVISLDHFPFENLLIPTAITSILTLPNNIIIYTKLTLCNSCPDTFNRDRFQGAIGSAKSGHVDISKGLKXXXXXXXXXXXXXXXXXLTPVMPLPEIPTIQPCYA--GFCK----NSGKCLVKNYGPR---CDCGISGFTGNQCDQK 3798
             CN T GFYG  C   I  C  + C  N  C V       CYC++GF GD CEK I  C   KC NGGKCV +  S  C C  +++GK CE K + C   +  C   GKC  +NG   C C+              C    C+NGG C  ++ +   +C     Y G+ C               C  + C  G      +   F C C   G+ G  CD+++      +K PG  +     P+ S G +T M  +T  K G L  Y   DD +   +L +GR+     + +           V+DG  H + +   E    + +D  P + +        ++T    ++    L +             + +  + +  HV  S+ LK     G    I      +     L  + T Q C A   FC      +GKC      P+   C C  S F+G  CD+K
Sbjct:  893 TCNCTPGFYGVHCENQIDACYGSPCLNNATCKVAQAGRFNCYCNKGFEGDYCEKNIDDCVNSKCENGGKCVDLINSYRCDCPMEYEGKHCEDKLEYCTKKLNPCENNGKCIPINGSYSCMCSPGFTGNNCETNIDDCKNVECQNGGSC--VDGILSYDCLCRPGYAGQYCEIPPMMDMEYQKTDACQQSACGQGECVASQNSSDFTCKCH-EGFSGPSCDRQMS---VGFKNPGAYLAL--DPLASDGTIT-MTLRTTSKIGILLYY--GDDHFVSAELYDGRVKLVYYIGNFPASHMYSSVKVNDGLPHRISIRTSERKCFLQIDKNPVQIVENSGKSDQLITKGKEMLYIGGLPI-------------EKSQDAKRRFHVKNSESLK-----GCISSITINEVPINLQQALENVNTEQSCSATVNFCAGIDCGNGKCTNNALSPKGYMCQCD-SHFSGEHCDEK 1328          

HSP 2 Score: 78.1814 bits (191), Expect = 6.876e-14
Identity = 74/236 (31.36%), Postives = 98/236 (41.53%), Query Frame = 1
Query: 2098 CPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPC-KNGICQIVGNNRI-CNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGY 2787
            C  + C+N   C   +  K  C+C    FYG  C+ +  +C  +PC  N  C++    R  C C   GF G  CE  I  C N KC+N G C+       CDC    YEG+ CE                    ++L YC             K + P   C  NG C+  + S  C C  GFTG+ CE  I  C   +C NGG CV    S  C+C   + G+ CE P    + Y
Sbjct:  873 CLNSPCKNNAICETTSSRKYTCNCTPG-FYGVHCENQIDACYGSPCLNNATCKVAQAGRFNCYC-NKGFEGDYCEKNIDDCVNSKCENGGKCVDLINSYRCDCPME-YEGKHCE--------------------DKLEYCT------------KKLNP---CENNGKCIPINGSYSCMCSPGFTGNNCETNIDDCKNVECQNGGSCVDGILSYDCLCRPGYAGQYCEIPPMMDMEY 1070          

HSP 3 Score: 62.003 bits (149), Expect = 5.398e-9
Identity = 59/201 (29.35%), Postives = 90/201 (44.78%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDP--NPCK-NGICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCT-KTVYEGQLCETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI 2661
            C++N+  C  + C+N G+C ++  +   CDC   ++ G+ C+ K   C    NPC+ NG C  +  +  C C+  GFTG +CE  I  C N +CQN G C+   GI   DC  +  Y GQ CE P                 +  + Y   ++       C +  C Q  C  + N         C C EGF+G  C++ +
Sbjct:  944 CEKNIDDCVNSKCENGGKCVDLINS-YRCDC-PMEYEGKHCEDKLEYCTKKLNPCENNGKCIPINGSYSCMCS-PGFTGNNCETNIDDCKNVECQNGGSCV--DGILSYDCLCRPGYAGQYCEIPP----------------MMDMEYQKTDA-------CQQSACGQGECVASQN----SSDFTCKCHEGFSGPSCDRQM 1112          

HSP 4 Score: 52.7582 bits (125), Expect = 3.732e-6
Identity = 70/250 (28.00%), Postives = 92/250 (36.80%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGICQIVGNNRICNCTGTGFTGFDCEISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCE------TPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKP-----------ICSKDKCINGGKCVVVDRSP--FCVCAKDFQGKSCEK 2763
            C+  +  C  + C N   C      +  C C K  F G++C+           KN                         I  C N KC+N G C+       CDC    YEG+ CE      T K  L+ C NNG C+   +N    C+C S GF G  C   I  C    C   G+C+    S  C C  G+ G  CE P            C +  C   G+CV    S    C C + F G SC++
Sbjct:  905 CENQIDACYGSPCLNNATCKVAQAGRFNCYCNKG-FEGDYCE-----------KN-------------------------IDDCVNSKCENGGKCVDLINSYRCDCPME-YEGKHCEDKLEYCTKK--LNPCENNGKCI--PINGSYSCMC-SPGFTGNNCETNIDDCKNVECQNGGSCVDGILSYDCLCRPGYAGQYCEIPPMMDMEYQKTDACQQSAC-GQGECVASQNSSDFTCKCHEGFSGPSCDR 1110          
BLAST of notch-1 vs. Ensembl Celegans
Match: glp-1 (pep chromosome:WBcel235:III:9092241:9099698:1 gene:WBGene00001609.1 transcript:F02A9.6.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:glp-1)

HSP 1 Score: 78.9518 bits (193), Expect = 3.582e-14
Identity = 96/338 (28.40%), Postives = 136/338 (40.24%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGIC---QIVGNNRICNCTGTGFTGFDCEISR---CFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPYCVCNS------------TGFYGYRCNKPICPQNYCTKNGNCL--VRDDSAVCYCDEGFTGDKCEK----------PICSKDKCINGGKCVVVDRSPF-CVCAKDFQGKSCEKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGX--XXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERC 2985
            C+E +  C +N C     C N +     CDC   +  G +C+    +   N C +G C   +    N  C C  +G+ G  C   +        C NN  C    G   C C K  Y G+ CE     C    C N+G+C  +  NQ+P C C              +GF G  C+ P+   +    NG C    R  +  C C+  + GD+CE             C  + C+N   C+ +  S + C C   F G +CE+   C    C  GG C  VNG+ RCNC    + G   + +  + C    C+NGG+C    N   C C    YTG  C
Sbjct:  151 CEEGIDHCAQNECAEGSTCVN-SVYNYYCDCPIGK-SGRYCERTECALMGNICNHGRCIPNRDEDKNFRCVCD-SGYEGEFCNKDKNECLIEETCVNNSTCFNLHGDFTCTC-KPGYAGKYCEEAIDMCKDYVCQNDGYCA-HDSNQMPICYCEQGFTGQRCEIECPSGFGGIHCDLPLQRPHCSRSNGTCYNDGRCINGFCVCEPDYIGDRCEINRKDFKFPDIQSCKYNPCVNNATCIDLKNSGYSCHCPLGFYGLNCEQHLLCTPTTCANGGTCEGVNGVIRCNCP-NGFSGDYCEIKDRQLCSRHPCKNGGVCK---NTGYCECQ-YGYTGPTC 478          

HSP 2 Score: 76.2554 bits (186), Expect = 2.602e-13
Identity = 103/356 (28.93%), Postives = 143/356 (40.17%), Query Frame = 1
Query: 2164 DCKKTQFYGEFCDIKRPSCDPNPCKNGICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCPL--DFCLNNGHCLLNQVNQLPY-CVCNSTGFYGYRCNK---PICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVV-VDRSPFCVCAKDFQGKSCEKPKPCPVGY--------------------CLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXX---------XXXYCENGGIC-SIINNVFICNCSNVSYTGERCTNKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQK 3108
            DCK   F G         CD +PC NG+C        C C   G+ G  CE  I  C  ++C     C+       CDC      G+ CE  +C L  + C N+G C+ N+     + CVC+S G+ G  CNK       +  C  N  C        C C  G+ G  CE+ I  C    C N G C    ++ P C C + F G+ CE    CP G+                    C   G+C  +NG   C   + +Y+G +CE  +K              C N   C  + N+ + C+C  + + G  C   + C    C NGG CE   G   CNC   G+ G+ C+ K
Sbjct:  109 DCKTPLFSG------VNPCDSDPCNNGLCYPFYGGFQCICN-NGYGGSYCEEGIDHCAQNECAEGSTCVNSVYNYYCDCP-IGKSGRYCERTECALMGNIC-NHGRCIPNRDEDKNFRCVCDS-GYEGEFCNKDKNECLIEETCVNNSTCFNLHGDFTCTCKPGYAGKYCEEAIDMCKDYVCQNDGYCAHDSNQMPICYCEQGFTGQRCEIE--CPSGFGGIHCDLPLQRPHCSRSNGTCYNDGRC--INGFCVC---EPDYIGDRCEINRKDFKFPDIQSCKYNPCVNNATCIDLKNSGYSCHCP-LGFYGLNCEQHLLCTPTTCANGGTCEGVNGVIRCNCP-NGFSGDYCEIK 445          
BLAST of notch-1 vs. Ensembl Fly
Match: N (gene:FBgn0004647 transcript:FBtr0304659)

HSP 1 Score: 115.546 bits (288), Expect = 4.865e-25
Identity = 112/359 (31.20%), Postives = 161/359 (44.85%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGICQIVG-NNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQ-LCETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCE-KPKPCPVGYCLYGGKCRMVNGMPRCNCT-QTNYMGX--XXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCT-NKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            CQ+ + +C  N CQ  G C +       C C+     G+ C++    C  NPC NG   I G N+  C C   GFTG  CE  +  C +  C NNG+CI +    +C+C +  Y+   L +  +C  + C+N G C  + +N+   C C   G+ G RC   I  C  N C   G C  + ++  C C  G+TG KCE  I  C  + C NGG C+       CVC   F G+ CE K  PC    C    KC   +     +CT +  Y G+    +  +      C NG  C  +   + C C+   Y G  C  N   C    C+NGG C    G + C C + G+ G+ C+  ++
Sbjct:  636 CQKQINECESNPCQFDGHCQD-RVGSYYCQCQAGT-SGKNCEVNVNECHSNPCNNGATCIDGINSYKCQCV-PGFTGQHCEKNVDECISSPCANNGVCIDQVNGYKCECPRGFYDAHCLSDVDECASNPCVNEGRCE-DGINEF-ICHC-PPGYTGKRCELDIDECSSNPCQHGGTCYDKLNAFSCQCMPGYTGQKCETNIDDCVTNPCGNGGTCIDKVNGYKCVCKVPFTGRDCESKMDPCASNRCKNEAKCTPSSNFLDFSCTCKLGYTGRYCDEDIDECSLSSPCRNGASCLNVPGSYRCLCTK-GYEGRDCAINTDDCASFPCQNGGTCLDGIGDYSCLC-VDGFDGKHCETDIN 986          

HSP 2 Score: 101.293 bits (251), Expect = 8.879e-21
Identity = 113/357 (31.65%), Postives = 155/357 (43.42%), Query Frame = 1
Query: 2071 RACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKN-GICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCT-KTVYEGQLCET--PKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRC--NKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCE-KPKPCPVGYCLYGGKC-RMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCD 3102
            + C+ ++ +C  N CQ+ G CY+      +C C    + G+ C+     C  NPC N G C    N   C C    FTG DCE  +  C +++C+N   C       +  CT K  Y G+ C+    +C L     NG   LN V     C+C + G+ G  C  N   C    C   G CL       C C +GF G  CE  I  C    C NG  C     S  C C   F G +C+   + C    CL GG C   +NG   C+C           K  KC    C NG  C   NN + C+C +  +TG++C+  V  C  + C+NG  C   + +F C CS  G+ G+ CD
Sbjct:  786 KRCELDIDECSSNPCQHGGTCYD-KLNAFSCQCMPG-YTGQKCETNIDDCVTNPCGNGGTCIDKVNGYKCVCK-VPFTGRDCESKMDPCASNRCKNEAKCTPSSNFLDFSCTCKLGYTGRYCDEDIDECSLSSPCRNGASCLN-VPGSYRCLC-TKGYEGRDCAINTDDCASFPCQNGGTCLDGIGDYSCLCVDGFDGKHCETDINECLSQPCQNGATCSQYVNSYTCTCPLGFSGINCQTNDEDCTESSCLNGGSCIDGINGY-NCSCLAGYSGANCQYKLNKCDSNPCLNGATCHEQNNEYTCHCPS-GFTGKQCSEYVDWCGQSPCENGATCSQMKHQFSCKCS-AGWTGKLCD 1134          

HSP 3 Score: 91.6633 bits (226), Expect = 9.199e-18
Identity = 108/355 (30.42%), Postives = 146/355 (41.13%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKN-GICQIVGNNRICNCTGTGFTGFDCEIS--RCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            C+ N+ +C  + CQN+G C +   T   C C    F G  C+I    C  NPC N G C    N   C+C   GFTG  C+I+   C +  C+N GIC        C+C    Y G  CE     C  + C + G C+ + VN    C+C+  G+ GY C K I  C  N C  +G+C  R  S  C C  G +G  CE  +  C  + C NG  C+    S  C C   F G+ CEK     V  C+                                    C N G+C    N + C C    Y     ++   C  N C N G CE    +F C+C   GY G++C+  +D
Sbjct:  485 CETNINECESHPCQNEGSCLDDPGT-FRCVCMPG-FTGTQCEIDIDECQSNPCLNDGTCHDKINGFKCSCA-LGFTGARCQINIDDCQSQPCRNRGICHDSIAGYSCECPPG-YTGTSCEININDCDSNPC-HRGKCI-DDVNSFK-CLCDP-GYTGYICQKQINECESNPCQFDGHCQDRVGSYYCQCQAGTSGKNCEVNVNECHSNPCNNGATCIDGINSYKCQCVPGFTGQHCEKN----VDECI---------------------------------SSPCANNGVCIDQVNGYKCECPRGFYDAHCLSDVDECASNPCVNEGRCEDGINEFICHCP-PGYTGKRCELDID 793          

HSP 4 Score: 87.8113 bits (216), Expect = 1.062e-16
Identity = 106/356 (29.78%), Postives = 143/356 (40.17%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKN-GICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRM--VNGMPRCNCTQTNYMGX--XXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERC-TNKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            C  ++++C  N C+  G C N + +   C C  T + G+ CD K   C P+PC+N GIC+  G +  C C   GF G +CE     C  H CQN G CI       C C    + G+ C+     +D C    H                          P+C QN  T    C     S  C C  G+ G  C      C +  C  G  C+    S +C C K   G  C     C    C     C    +NG   C+C  T Y G     +  +      CE+ GIC      + CNCS   +TG RC TN   C  + C+N G+C    G F C C + G+ G QC+  +D
Sbjct:  214 CSYDIEECQSNPCKYGGTCVNTHGS-YQCMC-PTGYTGKDCDTKYKPCSPSPCQNGGICRSNGLSYECKCP-KGFEGKNCEQNYDDCLGHLCQNGGTCIDGISDYTCRCPPN-FTGRFCQD---DVDECAQRDH--------------------------PVC-QNGAT----CTNTHGSYSCICVNGWAGLDCSNNTDDCKQAACFYGATCIDGVGSFYCQCTKGKTGLLCHLDDACTSNPCHADAICDTSPINGSYACSCA-TGYKGVDCSEDIDECDQGSPCEHNGICVNTPGSYRCNCSQ-GFTGPRCETNINECESHPCQNEGSCLDDPGTFRCVC-MPGFTGTQCEIDID 528          

HSP 5 Score: 82.4185 bits (202), Expect = 4.506e-15
Identity = 108/350 (30.86%), Postives = 146/350 (41.71%), Query Frame = 1
Query: 2089 VKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNR----ICNCTGTGFTGFDCEIS---RCFNHKCQNNGICILKQGIPECDCT-KTVYEGQLCETPK-CPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCE---KPICSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGY-CLYGGKCRMVNGMPRCNCT-QTNYMGX----XXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKV-GCPDNYCKNGGACEIHRGKFGCNCS 3072
               C    CQN G C      K  C C  + + G++C+ + P C+   C+NG  CQ+   N      C C   GF    CEI+    C +  C N G C LK  + E  C     Y G+ CET   C    C N   C     +    C C   GF G  C+  I  C  N C   G C+    S  C C  G+TG  C+   KP CS   C NGG C     S  C C K F+GK+CE+     +G+ C  GG C  ++G+    C    N+ G+      ++  +     C+NG  C+  +  + C C N  + G  C+N    C    C  G  C    G F C C+
Sbjct:   59 AASCTSVGCQNGGTCVTQLNGKTYCACD-SHYVGDYCEHRNP-CNSMRCQNGGTCQVTFRNGRPGISCKCP-LGFDESLCEIAVPNACDHVTCLNGGTCQLKT-LEEYTCACANGYTGERCETKNLCASSPCRNGATCTALAGSSSFTCSC-PPGFTGDTCSYDIEECQSNPCKYGGTCVNTHGSYQCMCPTGYTGKDCDTKYKP-CSPSPCQNGGICRSNGLSYECKCPKGFEGKNCEQNYDDCLGHLCQNGGTC--IDGISDYTCRCPPNFTGRFCQDDVDECAQRDHPVCQNGATCTNTHGSYSCICVN-GWAGLDCSNNTDDCKQAACFYGATCIDGVGSFYCQCT 399          

HSP 6 Score: 82.4185 bits (202), Expect = 4.544e-15
Identity = 102/356 (28.65%), Postives = 134/356 (37.64%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYN-INETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCE-KPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGA--CEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            CQ N + C ++ C N G C + IN    +C      + G  C  K   CD NPC NG  C    N   C+C  +GFTG  C   +  C    C+N   C   +    C C+   + G+LC+          +     L Q+                 CN           NG C    +S VCYC +G+ G  C+K I  C    C NGG C  +  +  C C + FQG++CE     C    C  GG C        C+C               C    C N G C      F C C    + G RC   +  C  N C N G   C      + CNC   G+ G  C+ KVD
Sbjct: 1019 CQTNDEDCTESSCLNGGSCIDGINGYNCSC---LAGYSGANCQYKLNKCDSNPCLNGATCHEQNNEYTCHCP-SGFTGKQCSEYVDWCGQSPCENGATCSQMKHQFSCKCSAG-WTGKLCDVQTISCQDAADRKGLSLRQL-----------------CN-----------NGTCKDYGNSHVCYCSQGYAGSYCQKEIDECQSQPCQNGGTCRDLIGAYECQCRQGFQGQNCELNIDDCAPNPCQNGGTCHDRVMNFSCSCPPGTMGIICEINKDDCKPGACHNNGSCIDRVGGFECVCQ-PGFVGARCEGDINECLSNPCSNAGTLDCVQLVNNYHCNCR-PGHMGRHCEHKVD 1339          

HSP 7 Score: 82.0333 bits (201), Expect = 6.413e-15
Identity = 83/254 (32.68%), Postives = 111/254 (43.70%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCEISR--CFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCE--KPICSKDKCINGGKCVVVDR--SPFCVCAKDFQGKSCE-------KPKPCPVG 2784
            CQ+ + +C    CQN G C ++      C C++  F G+ C++    C PNPC+NG  C     N  C+C   G  G  CEI++  C    C NNG CI + G  EC C +  + G  CE    +C  + C N G     Q+    +C C   G  G  C   +  C Q+ C   GNC +R     C C+ GF G  CE     C  + C   G CVV D      C C +   G+ CE        P PC  G
Sbjct: 1180 CQKEIDECQSQPCQNGGTCRDL-IGAYECQCRQG-FQGQNCELNIDDCAPNPCQNGGTCHDRVMNFSCSCP-PGTMGIICEINKDDCKPGACHNNGSCIDRVGGFECVC-QPGFVGARCEGDINECLSNPCSNAGTLDCVQLVNNYHCNCRP-GHMGRHCEHKVDFCAQSPCQNGGNCNIRQSGHHCICNNGFYGKNCELSGQDCDSNPC-RVGNCVVADEGFGYRCECPRGTLGEHCEIDTLDECSPNPCAQG 1427          

HSP 8 Score: 76.6406 bits (187), Expect = 3.165e-13
Identity = 111/363 (30.58%), Postives = 143/363 (39.39%), Query Frame = 1
Query: 2071 RACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSC---DPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCE-TPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNY-CTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCE-KPKPCPVGYCLYGGKCR-MVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCT-NKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            + C++N   C  + CQN G C +   +   C C    F G FC      C   D   C+NG  C     +  C C   G+ G DC      C    C     CI   G   C CTK    G LC     C  + C  +  C  + +N    C C +TG+ G  C++ I  C Q   C  NG C+    S  C C +GFTG +CE  I  C    C N G C+    +  CVC   F G  CE     C    CL  G C   +NG  +C+C       +       C  + C N GIC      + C C    YTG  C  N   C  N C   G C      F C C   GY G  C ++++
Sbjct:  288 KNCEQNYDDCLGHLCQNGGTCID-GISDYTCRCPPN-FTGRFCQDDVDECAQRDHPVCQNGATCTNTHGSYSCICV-NGWAGLDCSNNTDDCKQAACFYGATCIDGVGSFYCQCTKG-KTGLLCHLDDACTSNPCHADAICDTSPINGSYACSC-ATGYKGVDCSEDIDECDQGSPCEHNGICVNTPGSYRCNCSQGFTGPRCETNINECESHPCQNEGSCLDDPGTFRCVCMPGFTGTQCEIDIDECQSNPCLNDGTCHDKINGF-KCSCALGFTGARCQINIDDCQSQPCRNRGICHDSIAGYSCECP-PGYTGTSCEININDCDSNPCHR-GKCIDDVNSFKCLCD-PGYTGYICQKQIN 641          
BLAST of notch-1 vs. Ensembl Fly
Match: N (gene:FBgn0004647 transcript:FBtr0070507)

HSP 1 Score: 115.546 bits (288), Expect = 4.865e-25
Identity = 112/359 (31.20%), Postives = 161/359 (44.85%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGICQIVG-NNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQ-LCETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCE-KPKPCPVGYCLYGGKCRMVNGMPRCNCT-QTNYMGX--XXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCT-NKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            CQ+ + +C  N CQ  G C +       C C+     G+ C++    C  NPC NG   I G N+  C C   GFTG  CE  +  C +  C NNG+CI +    +C+C +  Y+   L +  +C  + C+N G C  + +N+   C C   G+ G RC   I  C  N C   G C  + ++  C C  G+TG KCE  I  C  + C NGG C+       CVC   F G+ CE K  PC    C    KC   +     +CT +  Y G+    +  +      C NG  C  +   + C C+   Y G  C  N   C    C+NGG C    G + C C + G+ G+ C+  ++
Sbjct:  636 CQKQINECESNPCQFDGHCQD-RVGSYYCQCQAGT-SGKNCEVNVNECHSNPCNNGATCIDGINSYKCQCV-PGFTGQHCEKNVDECISSPCANNGVCIDQVNGYKCECPRGFYDAHCLSDVDECASNPCVNEGRCE-DGINEF-ICHC-PPGYTGKRCELDIDECSSNPCQHGGTCYDKLNAFSCQCMPGYTGQKCETNIDDCVTNPCGNGGTCIDKVNGYKCVCKVPFTGRDCESKMDPCASNRCKNEAKCTPSSNFLDFSCTCKLGYTGRYCDEDIDECSLSSPCRNGASCLNVPGSYRCLCTK-GYEGRDCAINTDDCASFPCQNGGTCLDGIGDYSCLC-VDGFDGKHCETDIN 986          

HSP 2 Score: 101.293 bits (251), Expect = 8.879e-21
Identity = 113/357 (31.65%), Postives = 155/357 (43.42%), Query Frame = 1
Query: 2071 RACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKN-GICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCT-KTVYEGQLCET--PKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRC--NKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCE-KPKPCPVGYCLYGGKC-RMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCD 3102
            + C+ ++ +C  N CQ+ G CY+      +C C    + G+ C+     C  NPC N G C    N   C C    FTG DCE  +  C +++C+N   C       +  CT K  Y G+ C+    +C L     NG   LN V     C+C + G+ G  C  N   C    C   G CL       C C +GF G  CE  I  C    C NG  C     S  C C   F G +C+   + C    CL GG C   +NG   C+C           K  KC    C NG  C   NN + C+C +  +TG++C+  V  C  + C+NG  C   + +F C CS  G+ G+ CD
Sbjct:  786 KRCELDIDECSSNPCQHGGTCYD-KLNAFSCQCMPG-YTGQKCETNIDDCVTNPCGNGGTCIDKVNGYKCVCK-VPFTGRDCESKMDPCASNRCKNEAKCTPSSNFLDFSCTCKLGYTGRYCDEDIDECSLSSPCRNGASCLN-VPGSYRCLC-TKGYEGRDCAINTDDCASFPCQNGGTCLDGIGDYSCLCVDGFDGKHCETDINECLSQPCQNGATCSQYVNSYTCTCPLGFSGINCQTNDEDCTESSCLNGGSCIDGINGY-NCSCLAGYSGANCQYKLNKCDSNPCLNGATCHEQNNEYTCHCPS-GFTGKQCSEYVDWCGQSPCENGATCSQMKHQFSCKCS-AGWTGKLCD 1134          

HSP 3 Score: 91.6633 bits (226), Expect = 9.199e-18
Identity = 108/355 (30.42%), Postives = 146/355 (41.13%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKN-GICQIVGNNRICNCTGTGFTGFDCEIS--RCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            C+ N+ +C  + CQN+G C +   T   C C    F G  C+I    C  NPC N G C    N   C+C   GFTG  C+I+   C +  C+N GIC        C+C    Y G  CE     C  + C + G C+ + VN    C+C+  G+ GY C K I  C  N C  +G+C  R  S  C C  G +G  CE  +  C  + C NG  C+    S  C C   F G+ CEK     V  C+                                    C N G+C    N + C C    Y     ++   C  N C N G CE    +F C+C   GY G++C+  +D
Sbjct:  485 CETNINECESHPCQNEGSCLDDPGT-FRCVCMPG-FTGTQCEIDIDECQSNPCLNDGTCHDKINGFKCSCA-LGFTGARCQINIDDCQSQPCRNRGICHDSIAGYSCECPPG-YTGTSCEININDCDSNPC-HRGKCI-DDVNSFK-CLCDP-GYTGYICQKQINECESNPCQFDGHCQDRVGSYYCQCQAGTSGKNCEVNVNECHSNPCNNGATCIDGINSYKCQCVPGFTGQHCEKN----VDECI---------------------------------SSPCANNGVCIDQVNGYKCECPRGFYDAHCLSDVDECASNPCVNEGRCEDGINEFICHCP-PGYTGKRCELDID 793          

HSP 4 Score: 87.8113 bits (216), Expect = 1.062e-16
Identity = 106/356 (29.78%), Postives = 143/356 (40.17%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKN-GICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRM--VNGMPRCNCTQTNYMGX--XXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERC-TNKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            C  ++++C  N C+  G C N + +   C C  T + G+ CD K   C P+PC+N GIC+  G +  C C   GF G +CE     C  H CQN G CI       C C    + G+ C+     +D C    H                          P+C QN  T    C     S  C C  G+ G  C      C +  C  G  C+    S +C C K   G  C     C    C     C    +NG   C+C  T Y G     +  +      CE+ GIC      + CNCS   +TG RC TN   C  + C+N G+C    G F C C + G+ G QC+  +D
Sbjct:  214 CSYDIEECQSNPCKYGGTCVNTHGS-YQCMC-PTGYTGKDCDTKYKPCSPSPCQNGGICRSNGLSYECKCP-KGFEGKNCEQNYDDCLGHLCQNGGTCIDGISDYTCRCPPN-FTGRFCQD---DVDECAQRDH--------------------------PVC-QNGAT----CTNTHGSYSCICVNGWAGLDCSNNTDDCKQAACFYGATCIDGVGSFYCQCTKGKTGLLCHLDDACTSNPCHADAICDTSPINGSYACSCA-TGYKGVDCSEDIDECDQGSPCEHNGICVNTPGSYRCNCSQ-GFTGPRCETNINECESHPCQNEGSCLDDPGTFRCVC-MPGFTGTQCEIDID 528          

HSP 5 Score: 82.4185 bits (202), Expect = 4.506e-15
Identity = 108/350 (30.86%), Postives = 146/350 (41.71%), Query Frame = 1
Query: 2089 VKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNR----ICNCTGTGFTGFDCEIS---RCFNHKCQNNGICILKQGIPECDCT-KTVYEGQLCETPK-CPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCE---KPICSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGY-CLYGGKCRMVNGMPRCNCT-QTNYMGX----XXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKV-GCPDNYCKNGGACEIHRGKFGCNCS 3072
               C    CQN G C      K  C C  + + G++C+ + P C+   C+NG  CQ+   N      C C   GF    CEI+    C +  C N G C LK  + E  C     Y G+ CET   C    C N   C     +    C C   GF G  C+  I  C  N C   G C+    S  C C  G+TG  C+   KP CS   C NGG C     S  C C K F+GK+CE+     +G+ C  GG C  ++G+    C    N+ G+      ++  +     C+NG  C+  +  + C C N  + G  C+N    C    C  G  C    G F C C+
Sbjct:   59 AASCTSVGCQNGGTCVTQLNGKTYCACD-SHYVGDYCEHRNP-CNSMRCQNGGTCQVTFRNGRPGISCKCP-LGFDESLCEIAVPNACDHVTCLNGGTCQLKT-LEEYTCACANGYTGERCETKNLCASSPCRNGATCTALAGSSSFTCSC-PPGFTGDTCSYDIEECQSNPCKYGGTCVNTHGSYQCMCPTGYTGKDCDTKYKP-CSPSPCQNGGICRSNGLSYECKCPKGFEGKNCEQNYDDCLGHLCQNGGTC--IDGISDYTCRCPPNFTGRFCQDDVDECAQRDHPVCQNGATCTNTHGSYSCICVN-GWAGLDCSNNTDDCKQAACFYGATCIDGVGSFYCQCT 399          

HSP 6 Score: 82.4185 bits (202), Expect = 4.544e-15
Identity = 102/356 (28.65%), Postives = 134/356 (37.64%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYN-INETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCE-KPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGA--CEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            CQ N + C ++ C N G C + IN    +C      + G  C  K   CD NPC NG  C    N   C+C  +GFTG  C   +  C    C+N   C   +    C C+   + G+LC+          +     L Q+                 CN           NG C    +S VCYC +G+ G  C+K I  C    C NGG C  +  +  C C + FQG++CE     C    C  GG C        C+C               C    C N G C      F C C    + G RC   +  C  N C N G   C      + CNC   G+ G  C+ KVD
Sbjct: 1019 CQTNDEDCTESSCLNGGSCIDGINGYNCSC---LAGYSGANCQYKLNKCDSNPCLNGATCHEQNNEYTCHCP-SGFTGKQCSEYVDWCGQSPCENGATCSQMKHQFSCKCSAG-WTGKLCDVQTISCQDAADRKGLSLRQL-----------------CN-----------NGTCKDYGNSHVCYCSQGYAGSYCQKEIDECQSQPCQNGGTCRDLIGAYECQCRQGFQGQNCELNIDDCAPNPCQNGGTCHDRVMNFSCSCPPGTMGIICEINKDDCKPGACHNNGSCIDRVGGFECVCQ-PGFVGARCEGDINECLSNPCSNAGTLDCVQLVNNYHCNCR-PGHMGRHCEHKVD 1339          

HSP 7 Score: 82.0333 bits (201), Expect = 6.413e-15
Identity = 83/254 (32.68%), Postives = 111/254 (43.70%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCEISR--CFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCE--KPICSKDKCINGGKCVVVDR--SPFCVCAKDFQGKSCE-------KPKPCPVG 2784
            CQ+ + +C    CQN G C ++      C C++  F G+ C++    C PNPC+NG  C     N  C+C   G  G  CEI++  C    C NNG CI + G  EC C +  + G  CE    +C  + C N G     Q+    +C C   G  G  C   +  C Q+ C   GNC +R     C C+ GF G  CE     C  + C   G CVV D      C C +   G+ CE        P PC  G
Sbjct: 1180 CQKEIDECQSQPCQNGGTCRDL-IGAYECQCRQG-FQGQNCELNIDDCAPNPCQNGGTCHDRVMNFSCSCP-PGTMGIICEINKDDCKPGACHNNGSCIDRVGGFECVC-QPGFVGARCEGDINECLSNPCSNAGTLDCVQLVNNYHCNCRP-GHMGRHCEHKVDFCAQSPCQNGGNCNIRQSGHHCICNNGFYGKNCELSGQDCDSNPC-RVGNCVVADEGFGYRCECPRGTLGEHCEIDTLDECSPNPCAQG 1427          

HSP 8 Score: 76.6406 bits (187), Expect = 3.165e-13
Identity = 111/363 (30.58%), Postives = 143/363 (39.39%), Query Frame = 1
Query: 2071 RACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSC---DPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCE-TPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNY-CTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCE-KPKPCPVGYCLYGGKCR-MVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCT-NKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            + C++N   C  + CQN G C +   +   C C    F G FC      C   D   C+NG  C     +  C C   G+ G DC      C    C     CI   G   C CTK    G LC     C  + C  +  C  + +N    C C +TG+ G  C++ I  C Q   C  NG C+    S  C C +GFTG +CE  I  C    C N G C+    +  CVC   F G  CE     C    CL  G C   +NG  +C+C       +       C  + C N GIC      + C C    YTG  C  N   C  N C   G C      F C C   GY G  C ++++
Sbjct:  288 KNCEQNYDDCLGHLCQNGGTCID-GISDYTCRCPPN-FTGRFCQDDVDECAQRDHPVCQNGATCTNTHGSYSCICV-NGWAGLDCSNNTDDCKQAACFYGATCIDGVGSFYCQCTKG-KTGLLCHLDDACTSNPCHADAICDTSPINGSYACSC-ATGYKGVDCSEDIDECDQGSPCEHNGICVNTPGSYRCNCSQGFTGPRCETNINECESHPCQNEGSCLDDPGTFRCVCMPGFTGTQCEIDIDECQSNPCLNDGTCHDKINGF-KCSCALGFTGARCQINIDDCQSQPCRNRGICHDSIAGYSCECP-PGYTGTSCEININDCDSNPCHR-GKCIDDVNSFKCLCD-PGYTGYICQKQIN 641          
BLAST of notch-1 vs. Ensembl Fly
Match: Nrx-1 (gene:FBgn0038975 transcript:FBtr0334611)

HSP 1 Score: 105.145 bits (261), Expect = 5.281e-22
Identity = 176/709 (24.82%), Postives = 283/709 (39.92%), Query Frame = 1
Query:  154 PVSFTMPDAMLRLHPWNFAKYSSIELEFHTREPRGILFFVGSSTASTDS----IGLEIFNSNVYAFGKLLGKDFRIKLNPDNIRVSNGKFFKVAIQILATNYLVLKFDDVEIKEKIPTPGK---LEFNSYTYIGGVD------TITRLPWKAFSQTGFTGCINYIRINGERFLDTKQHSKQTEMQGAKTGVCQTSTARCLPGIC-GPGKCHERSYNMLDQSKNFYCDCSGTFKSYAYSAVDILRGEPCLIDSQRFQCNTKSYL-LYTFDKEKT-THYDDISIDFQTTNTKEPLFLMKSGTANVINTFLSAEVLAGQVIIIIKXXXXXXXXXXXXXXXXXXXXXDGQWHTLKLSRFAYNVEFYVDEQETISRGELYQSSLEEKFFNKVKEILLGSTTKPPGPDKCTGEIKNFFWNEEDLLGRKNKY-------GYYSSQL--VTEKXXXXXXXXXXXXXXXXCTLKPNHIYTVLNNIPLTNEGIILFIEFKT-KFDGIIWHAVNVFSSEDWMTL-LVNSNSIILAYSLPPNEGVHTIEMTRGGILIQDNTWHRVIINLNKPKEILYIHIDDVESLTNEIKLKNSKKELAEMNFISLSLGGISDNSQYTQFYNLLRKKNPEVSKLFSGPDELKFIGCLGDILVINSSYSGNLIQKPNVNSFPKESLFCRACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFC 2199
            PV+FT  ++ L L PW   K SSI  +F T+EP GI+     S          I +E+ N ++Y    L     +++ +    RV +G +  +   IL  N    K     +     TPG    LE + + Y+GGV       +     W A  + GF GC+  + ++G + +D    ++  +    K   C      C    C   G C       L+      CDCS T             G  C  +      N   ++ ++  + + T T  +++ I F+T+     L L+ S  +N  +  L   ++AG+V   ++       + + +  +  S LND  WHT++ SR A N+   VD    + RG L ++ L      +++ + LG         + T  + NF    + L+    +Y       G   S L   T K T   +     QP    T +  H Y  L  +   N   I F  FKT + +G++    N     D++ + LVN +   + Y+    +G  T+   +  I + DN WH+V I    PK       D  E ++  +   N   ELA + +I    GG+        F ++  K    +S   SG     F GCL  + + ++S S  L     V S    SL    C E   KC +N C N+G C        AC+C  T + G  C
Sbjct:  555 PVTFTTRESHLVLPPWETGKQSSISFKFRTKEPNGIIVLATGSKQPRAKNPVLIAIELLNGHIYIHLDLGSGASKVRAS--RRRVDDGDWHDL---ILRRNGRDAKVSVDGVWNDFRTPGDGTILELDGHMYLGGVGPAYNSVSWPAAIWTATLRQGFVGCLRDLVLSG-KAIDIAAFARVQDSASVKPS-CHVQANVCNGNPCLNGGTC-------LEGWNRPICDCSATLYG----------GPTCGRELATLAFNGSQHMTIWLGNGQGTKTQTEELVIRFKTSRPAG-LLLLTSAESNSPDR-LEIALVAGRVRASVR-----LSDREKNLLAGQSVLNDNNWHTIRFSRRASNLRLQVDGAPPV-RGMLSETILGRHSTMEIRSVHLGGLFHAEEEIQMTSTMPNFVGQMQGLVFNGQRYLDIVKSLGPELSALPSATFKLTARFVNSPAGQPYHAATFRSKHSYVGLAMLKAYNSISIDF-RFKTVEPNGLL--VFNGGRRNDFVAVELVNGH---IHYTFDLGDGPVTMR-DKSRIHMNDNRWHQVSIRRPGPKTHTLTVDDSFEIIS--LTGNNMHLELAGILYI----GGV--------FKDMYSKLPASISSR-SG-----FEGCLASLDLGDASPS--LTSDAVVPS----SLVVSGC-EGPTKCSQNACANRGNCVQ-QWNAYACECDMTSYTGPTC 1196          

HSP 2 Score: 65.855 bits (159), Expect = 5.379e-10
Identity = 83/366 (22.68%), Postives = 146/366 (39.89%), Query Frame = 1
Query:  220 SIELEFHTREPRGILFFVGSSTASTDSIGLEIFNSNV-YAFGKLLGKDFRIKLNPDNIRVSNGKFFKVAIQILATNYLVLKFDD-VEIKEKIPTPGKLEFNSYTYIGGV--DTITRLPWKAFSQTGFTGCINYIRINGERFLDTKQHSKQTEMQGAKTGVCQTSTARCLPGICGPGKCHERS----YNMLDQSKNFYCDCSGTFKSYAYSAVDILRGEPCLIDSQRFQ-CNTKSYLLYTF--DKEKTTHYDDISIDFQTTNTKEPLFLMKSGTANVINTFLSAEVLAGQVIIIIKXXXXXXXXXXXXXXXXXXXXXDGQWHTLKLSRFAYNVEFYVDEQETISRGELYQSSLEEKFFNKVKEILLG 1284
            SI+  F T EP G+L F G      D + +E+ N ++ Y F   LG       +   I +++ ++ +V+I+        L  DD  EI         LE     YIGGV  D  ++LP    S++GF GC+  + +               +   + T      ++  + G  GP KC + +     N + Q   + C+C  T  SY         G  C  +S  ++  N K  + YTF  + +  T  D+I++ F TT     L  ++S T      ++  E++ G + ++         +         + +ND  +H ++  R   N    +D+    +   L   S     FN +  + +G
Sbjct: 1005 SIDFRFKTVEPNGLLVFNGGR--RNDFVAVELVNGHIHYTFD--LGDGPVTMRDKSRIHMNDNRWHQVSIRRPGPKTHTLTVDDSFEIISLTGNNMHLELAGILYIGGVFKDMYSKLPASISSRSGFEGCLASLDLG--------------DASPSLTSDAVVPSSLVVSGCEGPTKCSQNACANRGNCVQQWNAYACECDMT--SYT--------GPTCYDESIAYEFGNNKGMVQYTFPENAQADTEEDNIALGFITTRPDAVLLRVESATT---QDYMELEIVEGNIFMVYN-----IGSVDLPLGEIGTKVNDNAYHVVRFQRKGGNATLQLDDYNVQA---LTPQSHHSTVFNTMSNVQVG 1331          
BLAST of notch-1 vs. Ensembl Fly
Match: crb (gene:FBgn0259685 transcript:FBtr0084603)

HSP 1 Score: 104.375 bits (259), Expect = 9.448e-22
Identity = 107/391 (27.37%), Postives = 157/391 (40.15%), Query Frame = 1
Query: 2080 QENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIK---RPSCDPNPC-KNGICQIVGNNRICNCT-GTGFTGFDCEIS--RCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCET--PKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI-CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEK----PKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXX----XXXXXYCENGGICSIINNVFICNCSNVSYTGERC------------------TNKVGCPDNY---------CKNGGAC-EIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            ++N   C KN C+N G C   +     C C      G+ C+ +    P C  NPC  NG C ++G +    C    G+ G  CE+    C +  CQNNG CI +     CDC+ T Y G  C+T   +C  + CLN G C             ++ G+Y                            C C +G+ G+ C++P+ C   +C+NGG C+       C+C  ++ G+ C+      + CP+     GGKC    G    NC  +   G                 C NGG CS+  N   C C+ V Y+G+RC                   N+  CP+N          C+NGG C ++  G + C C+  G+ G  C   VD
Sbjct:  302 KDNGSPCAKNPCENGGSCLENSRGDYQCFCDPNH-SGQHCETEVNIHPLCQTNPCLNNGACVVIGGSGALTCECPKGYAGARCEVDTDECASQPCQNNGSCIDRINGFSCDCSGTGYTGAFCQTNVDECDKNPCLNGGRCF------------DTYGWY---------------------------TCQCLDGWGGEICDRPMTCQTQQCLNGGTCLDKPIGFQCLCPPEYTGELCQIAPSCAQQCPIDSECVGGKCVCKPGSSGYNCQTSTGDGASALALTPINCNATNGKCLNGGTCSM--NGTHCYCA-VGYSGDRCEKAENCSPLNCQEPMVCVQNQCLCPENKVCNQCATQPCQNGGECVDLPNGDYECKCT-RGWTGRTCGNDVD 648          

HSP 2 Score: 100.523 bits (249), Expect = 1.611e-20
Identity = 83/252 (32.94%), Postives = 118/252 (46.83%), Query Frame = 1
Query: 2071 RACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDI-KRPSCDPNPCKNG-ICQ-----IVGNNRICNCTGTGFTGFDCEISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHC--LLNQVNQLPYCVCNSTGFYGYRCNKPI----CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCE--KPICSKDKCINGGKCVV---VDRSPFCVCAKDFQGKSCEKP 2766
            + C++N+ +C    C N G C ++  + + CDC +  + G  CD+ K+ +C+  PC+NG  CQ       GNN  C C   GF G  C+I  C    C N G+C+    +P C C+   Y G+LCE    +C  + C N G C  L+ +      C C  TGF G RC   I       +YC   G C  +  S  C C + + G  C    P  + D C NGG+CV         +C C + F GK+C  P
Sbjct: 1827 QHCEQNIDECADQPCHNGGNCTDLIASYV-CDCPE-DYMGPQCDVLKQMTCENEPCRNGSTCQNGFNASTGNNFTCTCV-PGFEGPLCDIPFCEITPCDNGGLCLTTGAVPMCKCSLG-YTGRLCEQDINECESNPCQNGGQCKDLVGRYE----CDCQGTGFEGIRCENDIDECNMEGDYCGGLGRCFNKPGSFQCICQKPYCGAYCNFTDPCNATDLCSNGGRCVESCGAKPDYYCECPEGFAGKNCTAP 2070          

HSP 3 Score: 91.2781 bits (225), Expect = 1.014e-17
Identity = 137/556 (24.64%), Postives = 211/556 (37.95%), Query Frame = 1
Query: 1528 ILFIEFKTKFDGIIWHAVNVFSSEDWMTLLVNSNSIILAYSLPPNEGVHTIEMTRGGILIQDNTWHRVIINLNKPK-----EILYIHIDDVESLTNEIKLKNSKKELAEMNFISLSLGGISDNSQYTQFYNLLRKKNPEVSKLFSGPDELKFIGCLGDILVINSSYSGNLIQKPNVNSFPKESLFCRACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKN-GICQIVGNNRICNCTGTGFTGFDC--EISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCET--PKCPLDFCLNNGHCLLNQVNQLPYCVCN-STGFYGYRC---------NKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPICSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKP-KPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMG---XXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVGC-PDNYCKNGGACEIHRGK---FGCNCSLTGYGGEQCDQKV 3111
            ++ I F+T+  G + +  NV   + +  + VN   + + + L     +H  E  R      D  W R+ +  +  K     +     +D   + + +I     +  +A      + LGG+ ++ Q                   S     +F GC+G+  V      G+L+    +  F    L+ R    NV        Q K + + +N T+            E C +    C  + CKN G CQ   +   C C   GF G DC  +I  C N +C NNG CI +     C C +  +EGQ CE    +C    C N G+C     + +   VC+    + G +C         N+P C      +NG      ++  C C  GF G  C+ P C    C NGG C+     P C C+  + G+ CE+    C    C  GG+C+ + G   C+C  T + G   +           YC   G C      F C C    Y G  C     C   + C NGG C    G    + C C   G+ G+ C   +
Sbjct: 1580 VIDIAFRTRAGGTLLYIDNV---DGFFEIGVNGGRVTITWKL---SALHFGESARFEKENTDGEWSRIYLRAHNSKLEGGWKGWESMVDPTPAFSTDIDQAAFQSLIATS--TQVYLGGMPESRQAR-------------GSTLSAQQGSQFKGCVGEARV------GDLL----LPYFSMAELYSRT---NVSV------QQKAQ-FRLNATRPE----------EGCIL----CFQSDCKNDGFCQSPSDEYACTCQ-PGFEGDDCGTDIDECLNTECLNNGTCINQVAAFFCQC-QPGFEGQHCEQNIDECADQPCHNGGNC----TDLIASYVCDCPEDYMGPQCDVLKQMTCENEP-CRNGSTCQNGFNASTGNNFTCTCVPGFEGPLCDIPFCEITPCDNGGLCLTTGAVPMCKCSLGYTGRLCEQDINECESNPCQNGGQCKDLVGRYECDCQGTGFEGIRCENDIDECNMEGDYCGGLGRCFNKPGSFQCICQK-PYCGAYCNFTDPCNATDLCSNGGRCVESCGAKPDYYCECP-EGFAGKNCTAPI 2071          

HSP 4 Score: 88.9669 bits (219), Expect = 5.689e-17
Identity = 125/458 (27.29%), Postives = 166/458 (36.24%), Query Frame = 1
Query: 2098 CPKNYCQNKGRCYNINET-KIACDCKKTQFYGEFCDIKRPSCDPNPCKN-GICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETP-KCPLDFCLNNGHCLLNQV----------------------NQLPY--------CVCNSTGFYGYRCNK---------PICPQNYCTKNGNCL----VRDDSAVCYCDEGFTGDKCEKP------------ICSKDKCI----------------NGGKCVVVDRSPF-CVCAKDFQGKSCE--------KPKPCPVGYC--------------------------------LYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXX-XXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            C  N C N G C  I  +  + C+C K  + G  C++    C   PC+N G C    N   C+C+GTG+TG  C+  +  C  + C N G C    G   C C    + G++C+ P  C    CLN G CL   +                       Q P         CVC   G  GY C            + P N    NG CL       +   CYC  G++GD+CEK             +C +++C+                NGG+CV +    + C C + + G++C          PK C  G C                                L G  C        C C Q  Y G+ CE          C NG  C    N F CNC     TG  C   +  C  + C NGG C    G F C+CS TGY GE C+  +D
Sbjct:  350 CQTNPCLNNGACVVIGGSGALTCECPKG-YAGARCEVDTDECASQPCQNNGSCIDRINGFSCDCSGTGYTGAFCQTNVDECDKNPCLNGGRCFDTYGWYTCQCLDG-WGGEICDRPMTCQTQQCLNGGTCLDKPIGFQCLCPPEYTGELCQIAPSCAQQCPIDSECVGGKCVCKP-GSSGYNCQTSTGDGASALALTPINCNATNGKCLNGGTCSMNGTHCYCAVGYSGDRCEKAENCSPLNCQEPMVCVQNQCLCPENKVCNQCATQPCQNGGECVDLPNGDYECKCTRGWTGRTCGNDVDECTLHPKICGNGICKNEKGSYKCYCTPGFTGVHCDSDVDECLSFPCLNGATCHNKINAYECVC-QPGYEGENCEVDIDECGSNPCSNGSTCIDRINNFTCNCI-PGMTGRICDIDIDDCVGDPCLNGGQCIDQLGGFRCDCSGTGYEGENCELNID 802          

HSP 5 Score: 86.2705 bits (212), Expect = 3.443e-16
Identity = 147/573 (25.65%), Postives = 218/573 (38.05%), Query Frame = 1
Query: 2008 YSGNLIQKPNVNSFPKESLFCRACQENVKKCPKNY---------CQNKGRCYNINETKIACDCKKTQFYGEFC--DIKRPSCDPNPCKNGICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETP----------------------------------------KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVV-----------------VDRSPF---------CVCAKDFQGKSCE-KPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXY--CENGGICSIINNVFICNCSNVSYTGERCTNKV-GCPDNYCKNGGAC------EIHRGKFGCNCSLTGYGGEQCDQKVDGVMC--------DYKEPGYAITAFKPPMVSSGIVTSMGFQTFVKTGTLFCYETADDKYWLIKLVNGR------LVADINGISFNMKTVVSDGRYHFLKVSRDETNFVISLD 3405
            YSG+  +K   N  P        C +N   CP+N          CQN G C ++      C C +  + G  C  D+   +  P  C NGIC+    +  C CT  GFTG  C+  +  C +  C N   C  K    EC C +  YEG+ CE                                           C  D CLN G C+ +Q+     C C+ TG+ G  C   I  C  N CT    CL R     C C  G+ G  CE+ I  C  + C   G C+                  V   PF         CVC     GK+CE     C    C   G C    G   C C +  + G  CE      ++Y  C+ G     I++ + C+C + +Y G+ C+  + GC  N C NGGAC      E+    + C C   G+ G++C++     M           +E GY I       + +G++       F  TG     E  +   ++++L+NGR      L+    G+    K  ++D  +H + V+ + ++ V+S +
Sbjct:  573 YSGDRCEKAE-NCSPLNCQEPMVCVQNQCLCPENKVCNQCATQPCQNGGECVDLPNGDYECKCTRG-WTGRTCGNDVDECTLHPKICGNGICKNEKGSYKCYCT-PGFTGVHCDSDVDECLSFPCLNGATCHNKINAYECVC-QPGYEGENCEVDIDECGSNPCSNGSTCIDRINNFTCNCIPGMTGRICDIDIDDCVGDPCLNGGQCI-DQLGGF-RCDCSGTGYEGENCELNIDECLSNPCTNGAKCLDRVKDYFCDCHNGYKGKNCEQDINECESNPCQYNGNCLERSNITLYQMSRITDLPKVFSQPFSFENASGYECVCVPGIIGKNCEININECDSNPCSKHGNCNDGIGTYTCEC-EPGFEGTHCEINIDECDRYNPCQRGTCYDQIDD-YDCDC-DANYGGKNCSVLLKGCDQNPCLNGGACLPYLINEVTH-LYNCTCE-NGFQGDKCEKTTTLSMVATSLISVTTEREEGYDINLQFRTTLPNGVL------AFGTTG-----EKNEPVSYILELINGRLNLHSSLLNKWEGVFIGSK--LNDSNWHKVFVAINTSHLVLSAN 1121          

HSP 6 Score: 84.7297 bits (208), Expect = 8.758e-16
Identity = 82/276 (29.71%), Postives = 113/276 (40.94%), Query Frame = 1
Query: 2326 CFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCE---KPICSKDKCINGGKC-----VVVDRSPFCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            CF   C+N+G C        C C +  +EG  C T   +C    CLNNG C+ NQV    +C C   GF G  C + I  C    C   GNC     S VC C E + G +C+   +  C  + C NG  C          +  C C   F+G  C+                     +P C  T                   C+NGG+C     V +C CS + YTG  C   +  C  N C+NGG C+   G++ C+C  TG+ G +C+  +D
Sbjct: 1760 CFQSDCKNDGFCQSPSDEYACTC-QPGFEGDDCGTDIDECLNTECLNNGTCI-NQVAAF-FCQCQP-GFEGQHCEQNIDECADQPCHNGGNCTDLIASYVCDCPEDYMGPQCDVLKQMTCENEPCRNGSTCQNGFNASTGNNFTCTCVPGFEGPLCD---------------------IPFCEITP------------------CDNGGLCLTTGAVPMCKCS-LGYTGRLCEQDINECESNPCQNGGQCKDLVGRYECDCQGTGFEGIRCENDID 1991          

HSP 7 Score: 69.707 bits (169), Expect = 3.717e-11
Identity = 76/240 (31.67%), Postives = 101/240 (42.08%), Query Frame = 1
Query: 2434 KCPLDFCLNN---GHCLLNQVNQLPYCVCNSTGFYGYRCNK---PICPQNYCTKNGNCL--VRDDSAVCYCDEGFTGDKCE-----KPICSKDKCINGGKCVVVDRSPF--CVCAKDFQGKSCE-KPKPCPVGYCLYGGKC-RMVNGMPRCNCTQTNYMGXX-XXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQC 3099
            + P +FCLN+   GH   +   +   C C +  + G  C K     C +N C   G+CL   R D   C+CD   +G  CE      P+C  + C+N G CVV+  S    C C K + G  CE     C    C   G C   +NG   C+C+ T Y G        +C +  C NGG C      + C C +  + GE C   + C    C NGG C      F C C    Y GE C
Sbjct:  263 RLPDNFCLNDPCMGHGTCSSSPEGYECRCTAR-YSGKNCQKDNGSPCAKNPCENGGSCLENSRGDYQ-CFCDPNHSGQHCETEVNIHPLCQTNPCLNNGACVVIGGSGALTCECPKGYAGARCEVDTDECASQPCQNNGSCIDRINGF-SCDCSGTGYTGAFCQTNVDECDKNPCLNGGRCFDTYGWYTCQCLD-GWGGEICDRPMTCQTQQCLNGGTCLDKPIGFQCLCPPE-YTGELC 497          

HSP 8 Score: 63.1586 bits (152), Expect = 3.696e-9
Identity = 83/270 (30.74%), Postives = 106/270 (39.26%), Query Frame = 1
Query: 2326 CFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPK---CPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCN-----KPICPQNYCTKNGNCLVRDDSAV--CYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCA-KDFQGKSCE-KPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVGCP-----DNYCKNGGACEIHRGKFGCNCSLT 3078
            C N  C  +G C       EC CT   Y G+ C+      C  + C N G CL N       C C+     G  C       P+C  N C  NG C+V   S    C C +G+ G +CE     C+   C N G C+       C C+   + G  C+     C    CL GG+C    G   C C    + G+ C++P  C  + C NGG C      F C C    YTGE C     C      D+ C  GG C    G  G NC  +
Sbjct:  269 CLNDPCMGHGTCSSSPEGYECRCTAR-YSGKNCQKDNGSPCAKNPCENGGSCLENSRGDY-QCFCDPN-HSGQHCETEVNIHPLCQTNPCLNNGACVVIGGSGALTCECPKGYAGARCEVDTDECASQPCQNNGSCIDRINGFSCDCSGTGYTGAFCQTNVDECDKNPCLNGGRCFDTYGWYTCQCLD-GWGGEICDRPMTCQTQQCLNGGTCLDKPIGFQCLCP-PEYTGELCQIAPSCAQQCPIDSECV-GGKCVCKPGSSGYNCQTS 532          
BLAST of notch-1 vs. Ensembl Fly
Match: Nrx-1 (gene:FBgn0038975 transcript:FBtr0334609)

HSP 1 Score: 104.375 bits (259), Expect = 1.038e-21
Identity = 175/709 (24.68%), Postives = 283/709 (39.92%), Query Frame = 1
Query:  154 PVSFTMPDAMLRLHPWNFAKYSSIELEFHTREPRGILFFVGSSTASTDS----IGLEIFNSNVYAFGKLLGKDFRIKLNPDNIRVSNGKFFKVAIQILATNYLVLKFDDVEIKEKIPTPGK---LEFNSYTYIGGVD------TITRLPWKAFSQTGFTGCINYIRINGERFLDTKQHSKQTEMQGAKTGVCQTSTARCLPGIC-GPGKCHERSYNMLDQSKNFYCDCSGTFKSYAYSAVDILRGEPCLIDSQRFQCNTKSYL-LYTFDKEKT-THYDDISIDFQTTNTKEPLFLMKSGTANVINTFLSAEVLAGQVIIIIKXXXXXXXXXXXXXXXXXXXXXDGQWHTLKLSRFAYNVEFYVDEQETISRGELYQSSLEEKFFNKVKEILLGSTTKPPGPDKCTGEIKNFFWNEEDLLGRKNKY-------GYYSSQL--VTEKXXXXXXXXXXXXXXXXCTLKPNHIYTVLNNIPLTNEGIILFIEFKT-KFDGIIWHAVNVFSSEDWMTL-LVNSNSIILAYSLPPNEGVHTIEMTRGGILIQDNTWHRVIINLNKPKEILYIHIDDVESLTNEIKLKNSKKELAEMNFISLSLGGISDNSQYTQFYNLLRKKNPEVSKLFSGPDELKFIGCLGDILVINSSYSGNLIQKPNVNSFPKESLFCRACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFC 2199
            PV+FT  ++ L L PW   K SSI  +F T+EP GI+     S          I +E+ N ++Y    L     +++ +    RV +G +  +   IL  N    K     +     TPG    LE + + Y+GGV       +     W A  + GF GC+  + ++G + +D    ++  +    K   C      C    C   G C       L+      CDCS T             G  C  +      N   ++ ++  + + T T  +++ I F+T+     L L+ S  +N  +  L   ++AG+V   ++       + + +  +  S LND  WHT++ SR A N+   VD    + RG L ++ L      +++ + LG         + T  + NF    + L+    +Y       G   S L   T K T   +     QP    T +  H Y  L  +   N  I +   FKT + +G++    N     D++ + LVN +   + Y+    +G  T+   +  I + DN WH+V I    PK       D  E ++  +   N   ELA + +I    GG+        F ++  K    +S   SG     F GCL  + + ++S S  L     V S    SL    C E   KC +N C N+G C        AC+C  T + G  C
Sbjct:  555 PVTFTTRESHLVLPPWETGKQSSISFKFRTKEPNGIIVLATGSKQPRAKNPVLIAIELLNGHIYIHLDLGSGASKVRAS--RRRVDDGDWHDL---ILRRNGRDAKVSVDGVWNDFRTPGDGTILELDGHMYLGGVGPAYNSVSWPAAIWTATLRQGFVGCLRDLVLSG-KAIDIAAFARVQDSASVKPS-CHVQANVCNGNPCLNGGTC-------LEGWNRPICDCSATLYG----------GPTCGRELATLAFNGSQHMTIWLGNGQGTKTQTEELVIRFKTSRPAG-LLLLTSAESNSPDR-LEIALVAGRVRASVR-----LSDREKNLLAGQSVLNDNNWHTIRFSRRASNLRLQVDGAPPV-RGMLSETILGRHSTMEIRSVHLGGLFHAEEEIQMTSTMPNFVGQMQGLVFNGQRYLDIVKSLGPELSALPSATFKLTARFVNSPAGQPYHAATFRSKHSYVGLAMLKAYNS-ISIDFRFKTVEPNGLL--VFNGGRRNDFVAVELVNGH---IHYTFDLGDGPVTMR-DKSRIHMNDNRWHQVSIRRPGPKTHTLTVDDSFEIIS--LTGNNMHLELAGILYI----GGV--------FKDMYSKLPASISSR-SG-----FEGCLASLDLGDASPS--LTSDAVVPS----SLVVSGC-EGPTKCSQNACANRGNCVQ-QWNAYACECDMTSYTGPTC 1196          

HSP 2 Score: 65.4698 bits (158), Expect = 6.703e-10
Identity = 83/366 (22.68%), Postives = 146/366 (39.89%), Query Frame = 1
Query:  220 SIELEFHTREPRGILFFVGSSTASTDSIGLEIFNSNV-YAFGKLLGKDFRIKLNPDNIRVSNGKFFKVAIQILATNYLVLKFDD-VEIKEKIPTPGKLEFNSYTYIGGV--DTITRLPWKAFSQTGFTGCINYIRINGERFLDTKQHSKQTEMQGAKTGVCQTSTARCLPGICGPGKCHERS----YNMLDQSKNFYCDCSGTFKSYAYSAVDILRGEPCLIDSQRFQ-CNTKSYLLYTF--DKEKTTHYDDISIDFQTTNTKEPLFLMKSGTANVINTFLSAEVLAGQVIIIIKXXXXXXXXXXXXXXXXXXXXXDGQWHTLKLSRFAYNVEFYVDEQETISRGELYQSSLEEKFFNKVKEILLG 1284
            SI+  F T EP G+L F G      D + +E+ N ++ Y F   LG       +   I +++ ++ +V+I+        L  DD  EI         LE     YIGGV  D  ++LP    S++GF GC+  + +               +   + T      ++  + G  GP KC + +     N + Q   + C+C  T  SY         G  C  +S  ++  N K  + YTF  + +  T  D+I++ F TT     L  ++S T      ++  E++ G + ++         +         + +ND  +H ++  R   N    +D+    +   L   S     FN +  + +G
Sbjct: 1005 SIDFRFKTVEPNGLLVFNGGR--RNDFVAVELVNGHIHYTFD--LGDGPVTMRDKSRIHMNDNRWHQVSIRRPGPKTHTLTVDDSFEIISLTGNNMHLELAGILYIGGVFKDMYSKLPASISSRSGFEGCLASLDLG--------------DASPSLTSDAVVPSSLVVSGCEGPTKCSQNACANRGNCVQQWNAYACECDMT--SYT--------GPTCYDESIAYEFGNNKGMVQYTFPENAQADTEEDNIALGFITTRPDAVLLRVESATT---QDYMELEIVEGNIFMVYN-----IGSVDLPLGEIGTKVNDNAYHVVRFQRKGGNATLQLDDYNVQA---LTPQSHHSTVFNTMSNVQVG 1331          
BLAST of notch-1 vs. Ensembl Zebrafish
Match: notch3 (notch receptor 3 [Source:ZFIN;Acc:ZDB-GENE-000329-5])

HSP 1 Score: 118.242 bits (295), Expect = 9.302e-26
Identity = 121/389 (31.11%), Postives = 168/389 (43.19%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGICQIVGNNRICNCTGTGFTGFDCEISR--CFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVN-----QLPY----------------------CVCNSTGFYGYRCNKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKP-CPVGYCLYGGKCR-MVNGMPRCNCTQTNYMGXXXXXXXXXXXXY-CENGGICSIINNVFICNCSNVSYTGERCTNKVGC--PDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVDGVMCD 3129
            C++ + +C  N C+N G C + +E    C C +  F+  +C  +   C  NPC +G C+   N   C+C   G+ G +C++ R  C    CQN G C  +     C C +  + G LC+    +C    CLN G C+    +     + PY                      CV ++  + GY+CN     Q+ C   G+C    +S  C C  GFTG +C   +  C    C NGG C     S  C C   F G  CE   P C    C  GG C   +NG  +C C +T + G  C+      +   C NGGIC      + C+C    YTG RC   V    P N CKNGG C      F C+C L G+ G  CD  + GV C+
Sbjct:  630 CKDEIDECQSNPCRNGGTCVD-DENGFHCQCPEG-FHDPYCYSQVDECASNPCLHGTCRDDPNGYRCDCE-PGWVGKNCDLDRNDCLPSPCQNAGTCFDQLNGFTCKC-RQGFRGNLCQVNINECASSPCLNQGTCVDGVASFTCLCEPPYSGPTCAELLTPCSPNPCANHASCV-HTPDYLGYQCNCQPGWQDPCLNGGSCTDGVNSFRCSCLPGFTGARCATELNECQSVPCKNGGTCTDYVNSYTCTCKPGFTGLLCETNVPDCTESSCFNGGTCTDGINGF-KCTC-RTGFTGDYCQYEVNECDSQPCLNGGICQDAMESYRCSCPK-GYTGPRCQYPVDWCRPSNPCKNGGRCRQKDASFTCDC-LGGWSGRYCD--IPGVSCE 1007          

HSP 2 Score: 96.2857 bits (238), Expect = 4.430e-19
Identity = 103/322 (31.99%), Postives = 139/322 (43.17%), Query Frame = 1
Query: 2113 CQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCE-------TPKCP--LDFCLNNGHCLLNQVNQLPYCVCN-STGFYGYRCNKPI--CPQNYCTKNG--NCLVRDDSAVCYCDEGFTGDKCEK--PICSKDKCINGGKCVVVDRSP---FCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGX--XXXXXXXXXXXYCENGGICSIINN--VFICNCSNVSYTGERCTNKVG 3000
            C + G C N   T   C C    + G +C+ +   C+  PC NG  C+       C+C   G+ G +CE  ++ C +H CQN G CI   G   C C      G LCE       TP  P  +  C NNG C    V+++    CN   GF G RC   I  C  N C  +   +C+   +   C C  GFTG  C+    +C    C NGG C +   SP    C C   + G +CE+   C    C  GG C +     RC C Q  + G   +      C  K C NGG+C+   +   F C C+N  + G+RC  K G
Sbjct: 1021 CLHGGHCVNTGNTHY-CKCP-ADYTGSYCESQFDHCEEKPCLNGATCRSYMGGFTCDCM-PGYEGNNCEREVNECQSHPCQNGGTCIDLVGHYICSCPPGTL-GVLCEINEDDCATPSWPRGMPKCQNNGTC----VDRVGGYRCNCPPGFTGERCEGDINECLSNPCNPSNSLDCIQLPNDYQCVCKPGFTGRGCQSRFSVCESQPCKNGGVCSLSGSSPPGYSCTCQLGYAGSNCERSMNCKELPCYNGGSCTLTTRGARCTCIQ-GFGGPLCQHRSNDGCSSKPCHNGGLCTEETSYPFFHCQCTN-GWKGKRCEQKTG 1332          

HSP 3 Score: 85.8853 bits (211), Expect = 5.263e-16
Identity = 107/381 (28.08%), Postives = 153/381 (40.16%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYN-INETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCE--ISRCF-NHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPL----------DFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCE--------KPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYC--ENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGK---FGCNCSLTGYGGEQCDQKVD 3114
            C+ NV  C ++ C N G C + IN  K  C   +T F G++C  +   CD  PC NG ICQ    +  C+C   G+TG  C+  +  C  ++ C+N G C  K     CDC    + G+ C+ P   C +          + CL+ GHC+        YC C +  + G  C      C +  C     C        C C  G+ G+ CE+ +  C    C NGG C+ +     C C     G  CE           P  +  C   G C    G  RCNC       +      +C    C   N   C  + N + C C    +TG  C ++   C    CKNGG C +       + C C L GY G  C++ ++
Sbjct:  884 CETNVPDCTESSCFNGGTCTDGINGFKCTC---RTGFTGDYCQYEVNECDSQPCLNGGICQDAMESYRCSCP-KGYTGPRCQYPVDWCRPSNPCKNGGRCRQKDASFTCDCLGG-WSGRYCDIPGVSCEVAARQRGRQTDELCLHGGHCV--NTGNTHYCKCPAD-YTGSYCESQFDHCEEKPCLNGATCRSYMGGFTCDCMPGYEGNNCEREVNECQSHPCQNGGTCIDLVGHYICSCPPGTLGVLCEINEDDCATPSWPRGMPKCQNNGTCVDRVGGYRCNCPPGFTGERCEGDINECLSNPCNPSNSLDCIQLPNDYQCVC-KPGFTGRGCQSRFSVCESQPCKNGGVCSLSGSSPPGYSCTCQL-GYAGSNCERSMN 1254          

HSP 4 Score: 85.1149 bits (209), Expect = 9.722e-16
Identity = 109/367 (29.70%), Postives = 161/367 (43.87%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQI--VGNNRICNCTGTGFTGFDC--EISRCF--NHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCE------KPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXX-XXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCT-NKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            C EN+  C    C N   C++       C+C   +  G  C +   +C  NPC  G +C    +    IC C   GF G  C  ++  C    + C++ G C+  +G  +C C +  Y G  CE    +C    C N+  CL +++ +   C+C   G+ G  C   I  C  N C  +G C    +   C C  GFTG  C+  I  C+   C NG KC+       C CA+ F+G+ CE      KP PC  G C+ G           CNC +  Y G +   +  +C    C+NGG C  + N +IC C + + +G  C  N   C  N C + G C+    ++ C C   G+ G QC  ++D
Sbjct:  287 CSENIDDCATAVCFNGATCHD-RVASFFCECPVGK-TGLLCHLDD-ACVSNPCNEGAVCDTNPLNGRAICTCP-AGFVGGACNQDMDECSIGANPCEHFGKCVNTEGSFQCQCGRG-YTGPRCEIDINECLSMPCQNDATCL-DRIGEF-TCIC-MPGYQGKYCEVDIDECESNPCVNDGICRDMVNGFTCTCQPGFTGTMCQIDIDECASTPCQNGAKCIDRPNGYECRCAEGFEGRLCESNIDNCKPDPCHHGTCVDGIASYT------CNC-EPGYTGYRCENQLNECHSNPCQNGGKCVDLVNKYICQCQHGT-SGTNCEINFDDCASNPC-DYGICKDGINRYECVCK-PGFTGPQCKDEID 635          

HSP 5 Score: 82.0333 bits (201), Expect = 8.295e-15
Identity = 105/366 (28.69%), Postives = 148/366 (40.44%), Query Frame = 1
Query: 2083 ENVKKCPKNYCQNKGRCYNINETKI---ACDCKKTQFYGEFCDIKRPSCDPNPCKNGI-CQIVGNNRICNCTGTGFTGFDC--EISRCFN-HKCQNNGICILKQGIPECDCTKTVYEGQLCETPK--CPLDFCLNNGHCLLNQVNQLPY-CVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI----CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSC-EKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSI--INNVFICNCSNVSYTGERCT---NKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            +++  C ++ C N   C +     I    C C++  F G+ C +   +C  +PC NG  C    N+  C+C   G+ G +C  +I  C    KC N GIC+   G   C+C  T Y G+ CE P   C    CLN G C  +Q     Y C C   GF G+ C   +  CP + C  NG C+   ++  C C   +TG  C + +       + C NGG C        CVC   + G  C E    C    C  G  C        C C      G  C     C    C  G +C    +N   IC C    + G  C    ++     N C++ G C    G F C C   GY G +C+  ++
Sbjct:   54 QHLDPCHRSPCLNAAACKSQVANSIPQYTCVCQRG-FRGQDCSLVD-ACATSPCANGARCTNWNNHYNCSCP-PGYQGKNCRNDIDECRKPGKCLNGGICMNTHGSFRCECL-TGYSGRTCEVPTQPCAPSQCLNGGTC--HQTGDHTYECAC-LPGFRGHNCEDNVDDCPGHKCMNNGICVDGVNTYNCQCPPEWTGQYCAEDVNECLMQPNACHNGGTCFNTIGGHTCVCVNGWTGDDCSENIDDCATAVCFNGATCHDRVASFFCECP-VGKTGLLCHLDDACVSNPCNEGAVCDTNPLNGRAICTCP-AGFVGGACNQDMDECSIGANPCEHFGKCVNTEGSFQCQCG-RGYTGPRCEIDIN 409          

HSP 6 Score: 80.8777 bits (198), Expect = 1.783e-14
Identity = 108/362 (29.83%), Postives = 148/362 (40.88%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFC--DIKRPSCDPNPCKN-GICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCE-TPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI----CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCE-KPKPCPVGYCLYGGKCR-MVNGMPRCNCTQTNYMGXX-XXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKV-GCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            C++NV  CP + C N G C +   T   C C   ++ G++C  D+      PN C N G C        C C   G+TG DC   I  C    C N   C  +     C+C      G LC     C  + C     C  N +N    C C   GF G  CN+ +       N C   G C+  + S  C C  G+TG +CE  I  C    C N   C+       C+C   +QGK CE     C    C+  G CR MVNG   C C Q  + G        +C    C+NG  C    N + C C+   + G  C + +  C  + C + G C      + CNC   GY G +C+ +++
Sbjct:  209 CEDNVDDCPGHKCMNNGICVDGVNT-YNCQCPP-EWTGQYCAEDVNECLMQPNACHNGGTCFNTIGGHTCVCV-NGWTGDDCSENIDDCATAVCFNGATCHDRVASFFCEC-PVGKTGLLCHLDDACVSNPCNEGAVCDTNPLNGRAICTC-PAGFVGGACNQDMDECSIGANPCEHFGKCVNTEGSFQCQCGRGYTGPRCEIDINECLSMPCQNDATCLDRIGEFTCICMPGYQGKYCEVDIDECESNPCVNDGICRDMVNGF-TCTC-QPGFTGTMCQIDIDECASTPCQNGAKCIDRPNGYECRCAE-GFEGRLCESNIDNCKPDPCHH-GTCVDGIASYTCNCE-PGYTGYRCENQLN 560          

HSP 7 Score: 79.7221 bits (195), Expect = 4.648e-14
Identity = 100/360 (27.78%), Postives = 133/360 (36.94%), Query Frame = 1
Query: 2071 RACQENVKKCPK-NYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKN-GICQIVGNNRI-CNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRM--VNGMPRCNCTQTNYMGX--XXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            + C+ ++ +C K   C N G C N + +   C+C  T + G  C++    C P+ C N G C   G++   C C   GF G +CE  +  C  HKC NNGIC+       C C    + GQ C           +   CL+                            N C   G C        C C  G+TGD C + I  C+   C NG  C     S FC C     G  C     C    C  G  C    +NG   C C      G   +           CE+ G C      F C C    YTG RC   +  C    C+N   C    G+F C C + GY G+ C+  +D
Sbjct:  129 KNCRNDIDECRKPGKCLNGGICMNTHGS-FRCECL-TGYSGRTCEVPTQPCAPSQCLNGGTCHQTGDHTYECACL-PGFRGHNCEDNVDDCPGHKCMNNGICVDGVNTYNCQCPPE-WTGQYCAE---------DVNECLMQ--------------------------PNACHNGGTCFNTIGGHTCVCVNGWTGDDCSENIDDCATAVCFNGATCHDRVASFFCECPVGKTGLLCHLDDACVSNPCNEGAVCDTNPLNGRAICTCPAGFVGGACNQDMDECSIGANPCEHFGKCVNTEGSFQCQCGR-GYTGPRCEIDINECLSMPCQNDATCLDRIGEFTCIC-MPGYQGKYCEVDID 447          

HSP 8 Score: 72.7886 bits (177), Expect = 4.979e-12
Identity = 83/268 (30.97%), Postives = 112/268 (41.79%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCD--------PNPCKNGIC-QIVGNNRICNCTGTGFTGFDCE--ISRCFNHKC--QNNGICILKQGIPECDCTKTVYEGQLCET--PKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI-CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI---CSKDKCINGGKCVVVDRSPF--CVCAKDFQGKSCEK--------PKPCPVGYCL 2793
            C+  V +C  + CQN G C ++    I C C      G  C+I    C         P    NG C   VG  R CNC   GFTG  CE  I+ C ++ C   N+  CI      +C C K  + G+ C++    C    C N G C L+  +   Y      G+ G  C + + C +  C   G+C +    A C C +GF G  C+      CS   C NGG C      PF  C C   ++GK CE+        P PCP+  C 
Sbjct: 1085 CEREVNECQSHPCQNGGTCIDLVGHYI-CSCPPGTL-GVLCEINEDDCATPSWPRGMPKCQNNGTCVDRVGGYR-CNCP-PGFTGERCEGDINECLSNPCNPSNSLDCIQLPNDYQCVC-KPGFTGRGCQSRFSVCESQPCKNGGVCSLSGSSPPGYSCTCQLGYAGSNCERSMNCKELPCYNGGSCTLTTRGARCTCIQGFGGPLCQHRSNDGCSSKPCHNGGLCTEETSYPFFHCQCTNGWKGKRCEQKTGSSAPLPSPCPIADCF 1347          

HSP 9 Score: 61.2326 bits (147), Expect = 1.603e-8
Identity = 81/302 (26.82%), Postives = 107/302 (35.43%), Query Frame = 1
Query: 2332 NHKCQNNGICILKQGIPECDCTKTVYEGQLCE-TPKCPLDFCLNNGHCLLNQVNQLPY--CVCNSTGFYGYRCN-KPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSK-DKCINGGKCVVVDRSPFCVCAKDFQGKSCEKP-KPCPVGYCLYGGKCRM-------------------------------------VNGMPRCNCT----QTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKV-GCPDNYCKNGGACEIHRGKFGCNCSLTGYG 3087
            +  C+N G+CI  +    C C +  Y G LC+    C    CLN   C     N +P   CVC   GF G  C+    C  + C     C   ++   C C  G+ G  C   I  C K  KC+NGG C+    S  C C   + G++CE P +PC    CL GG C                                       V+G+   NC      T     +           C NGG C        C C N  +TG+ C+  +  C    C NG  C      F C C +   G
Sbjct:   28 HRPCENGGMCIDSR----CLC-RPGYIGSLCQHLDPCHRSPCLNAAACKSQVANSIPQYTCVCQR-GFRGQDCSLVDACATSPCANGARCTNWNNHYNCSCPPGYQGKNCRNDIDECRKPGKCLNGGICMNTHGSFRCECLTGYSGRTCEVPTQPCAPSQCLNGGTCHQTGDHTYECACLPGFRGHNCEDNVDDCPGHKCMNNGICVDGVNTYNCQCPPEWTGQYCAEDVNECLMQPNACHNGGTCFNTIGGHTCVCVN-GWTGDDCSENIDDCATAVCFNGATCHDRVASFFCECPVGKTG 322          

HSP 10 Score: 56.225 bits (134), Expect = 6.253e-7
Identity = 62/214 (28.97%), Postives = 86/214 (40.19%), Query Frame = 1
Query: 2500 YCVCNSTGFYGYRCNKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEK-PICSKDKCINGGKC--VVVDRSP--FCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGX--XXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGAC-EIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            Y V NS G      ++P      C   G C+     + C C  G+ G  C+    C +  C+N   C   V +  P   CVC + F+G+ C     C    C  G +C   N    C+C    Y GK  + +  +      C NGGIC   +  F C C    Y+G  C      C  + C NGG C +     + C C L G+ G  C+  VD
Sbjct:   14 YLVHNSEGLLCVDTHRP------CENGGMCI----DSRCLCRPGYIGSLCQHLDPCHRSPCLNAAACKSQVANSIPQYTCVCQRGFRGQDCSLVDACATSPCANGARCTNWNNHYNCSCP-PGYQGKNCRNDIDECRKPGKCLNGGICMNTHGSFRCECL-TGYSGRTCEVPTQPCAPSQCLNGGTCHQTGDHTYECAC-LPGFRGHNCEDNVD 214          
BLAST of notch-1 vs. Ensembl Zebrafish
Match: notch1a (notch receptor 1a [Source:NCBI gene;Acc:30718])

HSP 1 Score: 114.39 bits (285), Expect = 1.156e-24
Identity = 122/408 (29.90%), Postives = 165/408 (40.44%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRI--CNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCE--KPICSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEK------PKP-----------------CPVGY----------------CLYGGKCRMVNGMPRCNCTQTNYMG-----------XXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            CQ N+ +C  N C N+G C + +     C+C    + GE C+     C P PCKNG +C+   + +   CNC   G+ G  CE  I+ C  + C N G+C   +G  +C C    + G LCE     C  + C N G C  ++VN    CVC   GF G RC + I  C    C   GNC    +S  C C  GF+G  CE   P C++  C NGG CV    S  CVC   F G  C+        +P                 CP GY                C  GG C        C C  + + G               +        C + G C    N  +C C    YTG  C  +V  C  N C+NG  C  + G + C C + GY G  C ++++
Sbjct:    4 CQMNINECASNPCLNQGSCID-DVAGFKCNCM-LPYTGEVCENVLAPCSPRPCKNGGVCRESEDFQSFSCNCP-AGWQGQTCEVDINECVRNPCTNGGVCENLRGGFQCRCNPG-FTGALCENDIDDCEPNPCSNGGVCQ-DRVNGF-VCVC-LAGFRGERCAEDIDECVSAPCRNGGNCTDCVNSYTCSCPAGFSGINCEINTPDCTESSCFNGGTCVDGISSFSCVCLPGFTGNYCQHDVNECDSRPCQNGGSCQDGYGTYKCTCPHGYTGLNCQSLVRWCDSSPCKNGGSCWQQGASFTCQCA-SGWTGIYCDVPSVSCEVAARQQGVSVAVLCRHAGQCVDAGNTHLCRC-QAGYTGSYCQEQVDECQPNPCQNGATCTDYLGGYSCEC-VPGYHGMNCSKEIN 401          

HSP 2 Score: 85.5001 bits (210), Expect = 6.317e-16
Identity = 92/307 (29.97%), Postives = 128/307 (41.69%), Query Frame = 1
Query: 2113 CQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDC--EISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCE----------TPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNG--NCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSP---FCVCAKDFQGKSCE-KPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXX--XXXYCENGGICSIINNVFICNCS 2958
            C++ G+C +   T + C C+   + G +C  +   C PNPC+NG  C        C C   G+ G +C  EI+ C +  CQN G CI      +C C +   +G  CE           P      C N G C +++V     CVC   GF G RC   +  C  + C  +G  NC+   +   C C  G+TG +CE     C    C NGG C V   +     C C   + G SCE   + C    C  G  C   +  PRC C    + G +C+           C NGG C  I++     CS
Sbjct:  332 CRHAGQCVDAGNTHL-CRCQAG-YTGSYCQEQVDECQPNPCQNGATCTDYLGGYSCECV-PGYHGMNCSKEINECLSQPCQNGGTCIDLVNTYKCSCPRGT-QGVHCEIDIDDCSPSVDPLTGEPRCFNGGRC-VDRVGGY-GCVC-PAGFVGERCEGDVNECLSDPCDPSGSYNCVQLINDFRCECRTGYTGKRCETVFNGCKDTPCKNGGTCAVASNTKHGYICKCQPGYSGSSCEYDSQSCGSLRCRNGATCVSGHLSPRCLCA-PGFSGHECQTRMDSPCLVNPCYNGGTCQPISDAPFYRCS 630          
BLAST of notch-1 vs. Ensembl Zebrafish
Match: notch1b (notch receptor 1b [Source:ZFIN;Acc:ZDB-GENE-990415-183])

HSP 1 Score: 110.923 bits (276), Expect = 1.419e-23
Identity = 114/373 (30.56%), Postives = 161/373 (43.16%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKN-GICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRC--NKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCE------KPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMG-----------XXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            CQ N+ +C  N C N+G C + +     C+C    + G+ C++    C  NPC+N  ICQ    +  C+C   G+TG +CE  I  C  + C N G C        C C    + G  CE    +C  + C N  +C  + VN    C C   GF G  C  N P C ++ C   G C+   +S  C C +GFTG+ C+  I  C    C+NGG C     +  C C + + G +C+      KP PC       GG CR       C C QT + G              ++      + C N G C    N   C+C    YTG  C  +V  C  N C+NG  C  + G + C C + GY G  C  +++
Sbjct:  808 CQTNINECASNPCLNQGTCID-DVAGYKCNCL-LPYTGQTCEVDINECVKNPCRNDAICQNSIGSYKCSCK-AGYTGRNCETDIDDCKPNPCSNGGFCKDAVNAFACTCLPG-FRGGRCEEDINECESNPCKNGANCT-DCVNSY-TCTC-PPGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPKGFTGNYCQHDINECDSRPCMNGGTCQDSYGTYKCTCPQGYHGLNCQELVNWCKPSPCK-----NGGICRQSGTRYSCQC-QTGWTGLYCDVPSVSCEVAAKQQGVDVVRLCRNSGQCLDAGNTHYCHCQ-AGYTGSYCEEQVDECIPNPCQNGATCTDYLGGYSCEC-VPGYHGVNCSDEIN 1165          

HSP 2 Score: 93.2041 bits (230), Expect = 3.765e-18
Identity = 111/363 (30.58%), Postives = 150/363 (41.32%), Query Frame = 1
Query: 2053 KESLFCRACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGICQIVGNNRICNCTGTGFTGFDCEIS--RCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCPLDFCLNN----GHCLLNQVNQLPYCVCNSTGFYGYRC--NKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCE-KPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXX-XXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCD 3102
            +     R C+ N+ +C    CQN G C +  E    C C K    G  C+I    C  NPC  G C    N   C C   G+TG  C I+   C  + C N G C+       C C +  Y    C++    L+ CL+N    GHC  ++VN    C+C+S G+ G  C  N   C  N C   G C       VC C  GF+G  C+  I  C+ + C+N G C+       C C   + G++CE     C    C     C+   G  +C+C +  Y G+        C    C NGG C    N F C C    + G RC   +  C  N CKNG  C      + C C   G+ G  C+
Sbjct:  612 RAGFMGRLCEININECLSQPCQNGGTCQD-RENAYLCVCPKGTA-GANCEINLDDCQSNPCDFGRCIDKINGYECACE-PGYTGKMCNINIDECAINPCHNGGTCVDGVNGFTCLC-REGYHDTTCQSQ---LNECLSNPCIHGHCE-DKVNGY-NCICDS-GWSGVNCDINNNECESNPCMNGGTCKDMTSGYVCTCRAGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGQTCEVDINECVKNPCRNDAICQNSIGSYKCSC-KAGYTGRNCETDIDDCKPNPCSNGGFCKDAVNAFACTCL-PGFRGGRCEEDINECESNPCKNGANCTDCVNSYTCTCP-PGFSGIHCE 961          

HSP 3 Score: 82.4185 bits (202), Expect = 7.275e-15
Identity = 103/360 (28.61%), Postives = 143/360 (39.72%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCD--PNPCKN-GICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCE-TPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI----CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCE-KPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            C+EN+  CP + C N G C +   T   C CK  ++ G+FC      CD  PN C+N G C        C C   G+TG DC   I  C +  C     C  +     C+C      G LC     C  + C    +C  N VN    C C   G+ G  C++ +       N C   G C+    S  C C +G+ G +CE  I  C    C N   C+       C+C   ++G  C+     C    CL  GKC       +C C       +      +C    C+NG  C    N++ C C+   YTG+ C   V  C  N C   G C+     F C C   G+ G  C+  ++
Sbjct:  274 CEENIDDCPDHRCLNGGTCVDGVNT-YNCQCKP-EWTGQFCTEDVNECDLMPNSCQNGGTCLNTQGGYNCVCV-NGWTGDDCSENIDDCADAACHTGATCHDRVASFLCECPHG-RTGLLCHLDDACISNPCQKGSNCDTNPVNGKAICTC-PLGYVGPACDQDVDECSLGANPCEHAGKCINTKGSFQCKCLQGYVGARCELDINECLSTPCQNDATCLDQIGGFHCICMPGYEGVFCQINTDECASMPCLNNGKCIDKINNYQCECPTGFSGSQCQFDIDECASTPCKNGAKCMDGPNMYTCQCTE-GYTGQHCETDVDECLSNPCHY-GTCKDGLASFTCVCR-AGFMGRLCEININ 625          

HSP 4 Score: 80.8777 bits (198), Expect = 1.729e-14
Identity = 88/308 (28.57%), Postives = 119/308 (38.64%), Query Frame = 1
Query: 2113 CQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDC--EISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCE----------TPKCPLDFCLNNGHCL----------------------LNQVNQLP-------------YCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSA---VCYCDEGFTGDKCE--KPICSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPK--PCPVGYCLYGGKCRMVNGMPRCNCT-QTNYMG 2862
            C+N G+C +   T   C C+   + G +C+ +   C PNPC+NG  C        C C   G+ G +C  EI+ C +  CQN G CI      +C C +   +G  CE           P      C N G C+                      +N+    P              C C  TG+ G  C+K    C    C   G C V  ++    +C C  GFTG  CE     C   +C NGG CV   +SP C+C   F G  C+ P    C    C  GG C  +   P  +C   TN+ G
Sbjct: 1096 CRNSGQCLDAGNTHY-CHCQAG-YTGSYCEEQVDECIPNPCQNGATCTDYLGGYSCECV-PGYHGVNCSDEINECLSQPCQNGGTCIDLINTYKCSCPRGT-QGVHCEINIDDCTPFTDPITHEPKCFNQGRCVDRVGGYHCICPPGYVGERCEGDVNECLSNPCGTHSCIQLKNNYRCECR-TGYTGQHCDKVFDGCKGKPCRNGGTCAVASNTPHGFICKCPPGFTGSTCEYDAHACGSLQCKNGGTCVSGHKSPKCLCTPAFTGPECQDPSGGHCTTNPCYNGGTCEYITEEPYYHCICPTNFNG 1398          

HSP 5 Score: 72.7886 bits (177), Expect = 6.057e-12
Identity = 101/362 (27.90%), Postives = 152/362 (41.99%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGI---CQIVGNNRICNCTGTGFTGFDCE--ISRCF--NHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRC--NKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKP-KPCPVGYCLYGGKCRMVNGMPRCNCT-QTNYMGXXXXXXXXXXXXY-CENGGICSIINNVFICNCSNVSYTGERCTNKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            C EN+  C    C     C++       C+C   +  G  C +   +C  NPC+ G       V    IC C   G+ G  C+  +  C    + C++ G CI  +G  +C C +  Y G  CE    +C    C N+  CL +Q+    +C+C   G+ G  C  N   C    C  NG C+ + ++  C C  GF+G +C+  I  C+   C NG KC+       C C + + G+ CE     C    C Y G C+  +G+    C  +  +MG+ CE          C+NGG C    N ++C C   +       N   C  N C + G C      + C C   GY G+ C+  +D
Sbjct:  352 CSENIDDCADAACHTGATCHD-RVASFLCECPHGR-TGLLCHLDD-ACISNPCQKGSNCDTNPVNGKAICTCP-LGYVGPACDQDVDECSLGANPCEHAGKCINTKGSFQCKCLQG-YVGARCELDINECLSTPCQNDATCL-DQIGGF-HCIC-MPGYEGVFCQINTDECASMPCLNNGKCIDKINNYQCECPTGFSGSQCQFDIDECASTPCKNGAKCMDGPNMYTCQCTEGYTGQHCETDVDECLSNPCHY-GTCK--DGLASFTCVCRAGFMGRLCEININECLSQPCQNGGTCQDRENAYLCVCPKGTAGANCEINLDDCQSNPC-DFGRCIDKINGYECACE-PGYTGKMCNINID 700          

HSP 6 Score: 63.929 bits (154), Expect = 2.893e-9
Identity = 98/365 (26.85%), Postives = 143/365 (39.18%), Query Frame = 1
Query: 2113 CQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGN----NRICNCTGTGFTGFDCEISR---CFNHKCQNNGICILKQ-GIPECDCTKTVYEGQLCETPK-CPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQ--NYCTKNGNCLVRDDSAVCYCDEGFTGDKCEK--PICSKDKCINGGKCV-----------VVDRSPFCV----CAKD---------FQGKSCEKP-KPCPVGYCLYGGKCRMVNGMPRCNCT----QTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKV-GCPDNYCKNGGACEIHRGKFGCNC 3069
            CQN G C    + +  C C    + G  C  + P C  +PC+NG +C+++ +    + +CNC+  G+T   C       C    C+N G C L       C C    + G+ C+    C  + C N G C     + L +C   +  F G  C + +  C Q  + C   G C     +  C C   +TG  CE     C+   C++GG CV           +  R  F +    C  D         F G++CE+    CP   CL GG C  V+G+   NC      T     +           C+NGG C      + C C N  +TG+ C+  +  C D  C  G  C      F C C
Sbjct:   27 CQNGGTCEPTADGRGECKCLDL-YAGPACQFRNP-CFQSPCRNGGVCRLITSANKVDFVCNCS-LGYTDRLCLTPTNNVCLGAPCRNGGTCELTSIHNYRCKCPPG-WSGKTCQQADPCASNPCANGGQCSPFDSDFLCHC---TPYFSGQTCKQDVNECAQIPSPCKNGGVCENGVGTYHCNCPAEYTGKHCESLYQPCNPSPCLHGGTCVQKGETSYECSCLPGRQEFVLIMRKCLNDYFLMLVFIGFSGQNCEENIDDCPDHRCLNGGTC--VDGVNTYNCQCKPEWTGQFCTEDVNECDLMPNSCQNGGTCLNTQGGYNCVCVN-GWTGDDCSENIDDCADAACHTGATCHDRVASFLCEC 381          

HSP 7 Score: 54.6842 bits (130), Expect = 1.883e-6
Identity = 48/161 (29.81%), Postives = 71/161 (44.10%), Query Frame = 1
Query: 2611 VCYCDEGFTGDKCEKP---ICSKDKCINGGKCVVVDRSPF-CVCAKDFQGKSCEKPKPCPVGYCLYGGKCRMVNGMPRCNCTQ--TNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCS 3072
            VC C  G+T   C  P   +C    C NGG C +     + C C   + GK+C++  PC    C  GG+C   +    C+CT   +    K+           C+NGG+C      + CNC    YTG+ C +    C  + C +GG C + +G+    CS
Sbjct:   83 VCNCSLGYTDRLCLTPTNNVCLGAPCRNGGTCELTSIHNYRCKCPPGWSGKTCQQADPCASNPCANGGQCSPFDSDFLCHCTPYFSGQTCKQDVNECAQIPSPCKNGGVCENGVGTYHCNCP-AEYTGKHCESLYQPCNPSPCLHGGTC-VQKGETSYECS 241          
BLAST of notch-1 vs. Ensembl Zebrafish
Match: notch1a (notch receptor 1a [Source:NCBI gene;Acc:30718])

HSP 1 Score: 109.383 bits (272), Expect = 4.956e-23
Identity = 122/408 (29.90%), Postives = 165/408 (40.44%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRI--CNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCE--KPICSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEK------PKP-----------------CPVGY----------------CLYGGKCRMVNGMPRCNCTQTNYMG-----------XXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            CQ N+ +C  N C N+G C + +     C+C    + GE C+     C P PCKNG +C+   + +   CNC   G+ G  CE  I+ C  + C N G+C   +G  +C C    + G LCE     C  + C N G C  ++VN    CVC   GF G RC + I  C    C   GNC    +S  C C  GF+G  CE   P C++  C NGG CV    S  CVC   F G  C+        +P                 CP GY                C  GG C        C C  + + G               +        C + G C    N  +C C    YTG  C  +V  C  N C+NG  C  + G + C C + GY G  C ++++
Sbjct:  787 CQMNINECASNPCLNQGSCID-DVAGFKCNCM-LPYTGEVCENVLAPCSPRPCKNGGVCRESEDFQSFSCNCP-AGWQGQTCEVDINECVRNPCTNGGVCENLRGGFQCRCNPG-FTGALCENDIDDCEPNPCSNGGVCQ-DRVNGF-VCVC-LAGFRGERCAEDIDECVSAPCRNGGNCTDCVNSYTCSCPAGFSGINCEINTPDCTESSCFNGGTCVDGISSFSCVCLPGFTGNYCQHDVNECDSRPCQNGGSCQDGYGTYKCTCPHGYTGLNCQSLVRWCDSSPCKNGGSCWQQGASFTCQCA-SGWTGIYCDVPSVSCEVAARQQGVSVAVLCRHAGQCVDAGNTHLCRC-QAGYTGSYCQEQVDECQPNPCQNGATCTDYLGGYSCEC-VPGYHGMNCSKEIN 1184          

HSP 2 Score: 99.7525 bits (247), Expect = 3.443e-20
Identity = 119/380 (31.32%), Postives = 161/380 (42.37%), Query Frame = 1
Query: 2071 RACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKN-GICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCT-KTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKP-CPVGYCLYGGKCRMVNGMP--RCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKV-GCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVDGVMCD--YKEPGYAITAF 3162
            R C  N+ +C  N C N G C ++    + C C+   F G  C +    C  NPC N G C        CNC    +TG  CE  ++ C    C+N G+C   +      C     ++GQ CE    +C  + C N G C    +     C CN  GF G  C   I  C  N C+  G C  R +  VC C  GF G++C + I  C    C NGG C     S  C C   F G +CE   P C    C  GG C  V+G+    C C              +C  + C+NGG C      + C C +  YTG  C + V  C  + CKNGG+C      F C C+ +G+ G  CD  V  V C+   ++ G ++   
Sbjct:  747 RNCDININECLSNPCVNGGTCKDMTSGYL-CTCRAG-FSGPNCQMNINECASNPCLNQGSCIDDVAGFKCNCM-LPYTGEVCENVLAPCSPRPCKNGGVCRESEDFQSFSCNCPAGWQGQTCEVDINECVRNPCTNGGVC--ENLRGGFQCRCN-PGFTGALCENDIDDCEPNPCSNGGVCQDRVNGFVCVCLAGFRGERCAEDIDECVSAPCRNGGNCTDCVNSYTCSCPAGFSGINCEINTPDCTESSCFNGGTC--VDGISSFSCVCLPGFTGNYCQHDVNECDSRPCQNGGSCQDGYGTYKCTCPH-GYTGLNCQSLVRWCDSSPCKNGGSCWQQGASFTCQCA-SGWTGIYCD--VPSVSCEVAARQQGVSVAVL 1114          

HSP 3 Score: 98.5969 bits (244), Expect = 7.916e-20
Identity = 119/421 (28.27%), Postives = 169/421 (40.14%), Query Frame = 1
Query: 2011 SGNLIQKPNVNSFPKE---SLFCRACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTV------------------------------------YEGQLCET--PKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICPQNYCTKN----GNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCE-KPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNV--FICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            SG  I K  +NSF  E         CQ +V +C    C+N  +C +    K  C+C    F G  C++    C  +PC  G+C+    +  C+C   G+TG  CE  I+ C +  C+N G C  ++    C C K                                      Y G +C      C L+ C N G C+ + VN    C+C   GF    C   +   N C+ N    G+CL + +S  C C+ G+ G  C+  I  C  + C+NGG C  +     C C   F G +C+     C    CL  G C       +CNC               C  + C+NGG+C    +   F CNC    + G+ C   +  C  N C NGG CE  RG F C C+  G+ G  C+  +D
Sbjct:  501 SGKCIDK--INSFHCECPKGFSGSLCQVDVDECASTPCKNGAKCTD-GPNKYTCECTPG-FSGIHCELDINECASSPCHYGVCRDGVASFTCDCR-PGYTGRLCETNINECLSQPCRNGGTCQDRENAYICTCPKGTTGVNCEINIDDCKRKPCDYGKCIDKINGYECVCEPGYSGSMCNINIDDCALNPCHNGGTCI-DGVNSF-TCLC-PDGFRDATC---LSQHNECSSNPCIHGSCLDQINSYRCVCEAGWMGRNCDININECLSNPCVNGGTCKDMTSGYLCTCRAGFSGPNCQMNINECASNPCLNQGSCIDDVAGFKCNCMLPYTGEVCENVLAPCSPRPCKNGGVCRESEDFQSFSCNCP-AGWQGQTCEVDINECVRNPCTNGGVCENLRGGFQCRCN-PGFTGALCENDID 908          

HSP 4 Score: 82.4185 bits (202), Expect = 6.036e-15
Identity = 99/351 (28.21%), Postives = 138/351 (39.32%), Query Frame = 1
Query: 2110 YCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKN-GIC--QIVGNNRICNCTGTGFTGFDCEISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETP---KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCN-KPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI----CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKP-KPCPVGYCLYGGKC-RMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG---CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            YCQN G C      + +C C    F G  C    P C+P+PC+N G+C  Q+ GN            G  C+              C+L             +  +LC TP    C    C N G C L  ++    C C   G+ G  C     C  N C   G C   +   +C C   F G  C + +     S   C NGG C+    S  C C  ++ G  C++  +PC    C  GG C +  +    C+C               C +  CENGG C    N + C+C +  +TG+ CT  V       N C+NGG C    G F C C + G+ G+ C + +D
Sbjct:   28 YCQNGGICEYKPSGEASCRCP-ADFVGAQCQFPNP-CNPSPCRNGGVCRPQMQGNE----------VGVKCD--------------CVLG------------FSDRLCLTPVNHACMNSPCRNGGTCSLLTLDTF-TCRCQ-PGWSGKTCQLADPCASNPCANGGQCSAFESHYICTCPPNFHGQTCRQDVNECAVSPSPCRNGGTCINEVGSYLCRCPPEYTGPHCQRLYQPCLPSPCRSGGTCVQTSDTTHTCSCLPGFTGQTCEHNVDDCTQHACENGGRCIDGINTYNCHC-DKHWTGQYCTEDVDECELSPNACQNGGTCHNTIGGFHCVC-VNGWTGDDCSENID 336          

HSP 5 Score: 81.2629 bits (199), Expect = 1.484e-14
Identity = 105/389 (26.99%), Postives = 151/389 (38.82%), Query Frame = 1
Query: 2071 RACQENVKKCPKNYCQNKGRCYN-INETKIACDCKKTQFYGEFC--DIKRPSCDPNPCKN-GICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCE-TPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI----CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCE-KPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKV---------DGVMCDYKEPGYAITAFK 3165
            + C+ NV  C ++ C+N GRC + IN     CD     + G++C  D+      PN C+N G C        C C   G+TG DC   I  C +  C +   C  +     C+C      G LC     C  + C    +C  N V+    C C   G+ G  CN+ I       N C   G CL    S  C C +G+ G +CE  +  C  + C N   C+       C+C   ++G  C+     C    CL  GKC        C C +            +C    C+NG  C+   N + C C+   ++G  C   +  C  + C   G C      F C+C   GY G  C+  +         +G  C  +E  Y  T  K
Sbjct:  251 QTCEHNVDDCTQHACENGGRCIDGINTYNCHCD---KHWTGQYCTEDVDECELSPNACQNGGTCHNTIGGFHCVCV-NGWTGDDCSENIDDCASAACSHGATCHDRVASFFCECPHG-RTGLLCHLDDACISNPCQKGSNCDTNPVSGKAICTC-PPGYTGSACNQDIDECSLGANPCEHGGRCLNTKGSFQCKCLQGYEGPRCEMDVNECKSNPCQNDATCLDQIGGFHCICMPGYEGVFCQINSDDCASQPCLNSGKCIDKINSFHCECPKGFSGSLCQVDVDECASTPCKNGAKCTDGPNKYTCECT-PGFSGIHCELDINECASSPCHY-GVCRDGVASFTCDCR-PGYTGRLCETNINECLSQPCRNGGTCQDRENAYICTCPK 630          

HSP 6 Score: 80.8777 bits (198), Expect = 1.800e-14
Identity = 93/307 (30.29%), Postives = 129/307 (42.02%), Query Frame = 1
Query: 2113 CQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDC--EISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCE----------TPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNG--NCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSP---FCVCAKDFQGKSCE-KPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXY--CENGGICSIINNVFICNCS 2958
            C++ G+C +   T + C C+   + G +C  +   C PNPC+NG  C        C C   G+ G +C  EI+ C +  CQN G CI      +C C +   +G  CE           P      C N G C +++V     CVC   GF G RC   +  C  + C  +G  NC+   +   C C  G+TG +CE     C    C NGG C V   +     C C   + G SCE   + C    C  G  C   +  PRC C    + G +C+     P     C NGG C  I++     CS
Sbjct: 1115 CRHAGQCVDAGNTHL-CRCQAG-YTGSYCQEQVDECQPNPCQNGATCTDYLGGYSCECV-PGYHGMNCSKEINECLSQPCQNGGTCIDLVNTYKCSCPRGT-QGVHCEIDIDDCSPSVDPLTGEPRCFNGGRC-VDRVGGY-GCVC-PAGFVGERCEGDVNECLSDPCDPSGSYNCVQLINDFRCECRTGYTGKRCETVFNGCKDTPCKNGGTCAVASNTKHGYICKCQPGYSGSSCEYDSQSCGSLRCRNGATCVSGHLSPRCLCA-PGFSGHECQTRMDSPCLVNPCYNGGTCQPISDAPFYRCS 1413          

HSP 7 Score: 79.337 bits (194), Expect = 5.461e-14
Identity = 101/360 (28.06%), Postives = 143/360 (39.72%), Query Frame = 1
Query: 2092 KKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDC--EISRCF--NHKCQNNGICILKQGIPECDCTKTVYEGQLCET--PKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI----CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSC-EKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSI--INNVFICNCSNVSYTGERCTNKV---GCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
              C  + C+N G C  +      C C+   + G+ C +  P C  NPC NG  C    ++ IC C    F G  C  +++ C      C+N G CI + G   C C    Y G  C+     C    C + G C+  Q +   +      GF G  C   +  C Q+ C   G C+   ++  C+CD+ +TG  C + +     S + C NGG C        CVC   + G  C E    C    C +G  C        C C      G  C     C    C+ G  C    ++   IC C    YTG  C   +       N C++GG C   +G F C C L GY G +C+  V+
Sbjct:  103 HACMNSPCRNGGTCSLLTLDTFTCRCQPG-WSGKTCQLADP-CASNPCANGGQCSAFESHYICTCP-PNFHGQTCRQDVNECAVSPSPCRNGGTCINEVGSYLCRCPPE-YTGPHCQRLYQPCLPSPCRSGGTCV--QTSDTTHTCSCLPGFTGQTCEHNVDDCTQHACENGGRCIDGINTYNCHCDKHWTGQYCTEDVDECELSPNACQNGGTCHNTIGGFHCVCVNGWTGDDCSENIDDCASAACSHGATCHDRVASFFCECPH-GRTGLLCHLDDACISNPCQKGSNCDTNPVSGKAICTCP-PGYTGSACNQDIDECSLGANPCEHGGRCLNTKGSFQCKC-LQGYEGPRCEMDVN 453          
BLAST of notch-1 vs. Ensembl Zebrafish
Match: notch3 (notch receptor 3 [Source:ZFIN;Acc:ZDB-GENE-000329-5])

HSP 1 Score: 103.605 bits (257), Expect = 2.244e-21
Identity = 111/370 (30.00%), Postives = 155/370 (41.89%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINE-TKIACDCKKTQFYGEFCDIKRPSCDPNPCKN-GICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRC--NKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPC--PVGYCLYGGKCRMVNGMPRCNCTQTNYMGX-----------XXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            C E +  C  N C N   C +  +     C+C+   + G  C+     C  NPCKN G C       +C+C   G+TG +CE  I+ C  + C N G C        C C    + G  C T   +C    C N G C  + VN    C C   GF G  C  N P C ++ C   G C    +   C C  GFTGD C+  +  C    C+NGG C     S  C C K + G  C+ P     P   C  GG+CR  +    C+C    + G+              +  +  ++ C +GG C    N   C C    YTG  C ++   C +  C NG  C  + G F C+C + GY G  C+++V+
Sbjct:  781 CAELLTPCSPNPCANHASCVHTPDYLGYQCNCQPG-WQGHLCNNDINECTSNPCKNRGTCTNTLGGYVCSCR-AGYTGPNCETDINDCSPNPCLNGGSCTDGVNSFRCSCLPG-FTGARCATELNECQSVPCKNGGTCT-DYVNSY-TCTCKP-GFTGLLCETNVPDCTESSCFNGGTCTDGINGFKCTCRTGFTGDYCQYEVNECDSQPCLNGGICQDAMESYRCSCPKGYTGPRCQYPVDWCRPSNPCKNGGRCRQKDASFTCDCL-GGWSGRYCDIPGVSCEVAARQRGRQTDELCLHGGHCVNTGNTHYCKCP-ADYTGSYCESQFDHCEEKPCLNGATCRSYMGGFTCDC-MPGYEGNNCEREVN 1141          

HSP 2 Score: 95.9005 bits (237), Expect = 5.309e-19
Identity = 103/322 (31.99%), Postives = 139/322 (43.17%), Query Frame = 1
Query: 2113 CQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCE-------TPKCP--LDFCLNNGHCLLNQVNQLPYCVCN-STGFYGYRCNKPI--CPQNYCTKNG--NCLVRDDSAVCYCDEGFTGDKCEK--PICSKDKCINGGKCVVVDRSP---FCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGX--XXXXXXXXXXXYCENGGICSIINN--VFICNCSNVSYTGERCTNKVG 3000
            C + G C N   T   C C    + G +C+ +   C+  PC NG  C+       C+C   G+ G +CE  ++ C +H CQN G CI   G   C C      G LCE       TP  P  +  C NNG C    V+++    CN   GF G RC   I  C  N C  +   +C+   +   C C  GFTG  C+    +C    C NGG C +   SP    C C   + G +CE+   C    C  GG C +     RC C Q  + G   +      C  K C NGG+C+   +   F C C+N  + G+RC  K G
Sbjct: 1072 CLHGGHCVNTGNTHY-CKCP-ADYTGSYCESQFDHCEEKPCLNGATCRSYMGGFTCDCM-PGYEGNNCEREVNECQSHPCQNGGTCIDLVGHYICSCPPGTL-GVLCEINEDDCATPSWPRGMPKCQNNGTC----VDRVGGYRCNCPPGFTGERCEGDINECLSNPCNPSNSLDCIQLPNDYQCVCKPGFTGRGCQSRFSVCESQPCKNGGVCSLSGSSPPGYSCTCQLGYAGSNCERSMNCKELPCYNGGSCTLTTRGARCTCIQ-GFGGPLCQHRSNDGCSSKPCHNGGLCTEETSYPFFHCQCTN-GWKGKRCEQKTG 1383          

HSP 3 Score: 84.7297 bits (208), Expect = 1.321e-15
Identity = 109/367 (29.70%), Postives = 161/367 (43.87%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQI--VGNNRICNCTGTGFTGFDC--EISRCF--NHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCE------KPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXX-XXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCT-NKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            C EN+  C    C N   C++       C+C   +  G  C +   +C  NPC  G +C    +    IC C   GF G  C  ++  C    + C++ G C+  +G  +C C +  Y G  CE    +C    C N+  CL +++ +   C+C   G+ G  C   I  C  N C  +G C    +   C C  GFTG  C+  I  C+   C NG KC+       C CA+ F+G+ CE      KP PC  G C+ G           CNC +  Y G +   +  +C    C+NGG C  + N +IC C + + +G  C  N   C  N C + G C+    ++ C C   G+ G QC  ++D
Sbjct:  287 CSENIDDCATAVCFNGATCHD-RVASFFCECPVGK-TGLLCHLDD-ACVSNPCNEGAVCDTNPLNGRAICTCP-AGFVGGACNQDMDECSIGANPCEHFGKCVNTEGSFQCQCGRG-YTGPRCEIDINECLSMPCQNDATCL-DRIGEF-TCIC-MPGYQGKYCEVDIDECESNPCVNDGICRDMVNGFTCTCQPGFTGTMCQIDIDECASTPCQNGAKCIDRPNGYECRCAEGFEGRLCESNIDNCKPDPCHHGTCVDGIASYT------CNC-EPGYTGYRCENQLNECHSNPCQNGGKCVDLVNKYICQCQHGT-SGTNCEINFDDCASNPC-DYGICKDGINRYECVCK-PGFTGPQCKDEID 635          

HSP 4 Score: 81.6481 bits (200), Expect = 1.185e-14
Identity = 105/366 (28.69%), Postives = 148/366 (40.44%), Query Frame = 1
Query: 2083 ENVKKCPKNYCQNKGRCYNINETKI---ACDCKKTQFYGEFCDIKRPSCDPNPCKNGI-CQIVGNNRICNCTGTGFTGFDC--EISRCFN-HKCQNNGICILKQGIPECDCTKTVYEGQLCETPK--CPLDFCLNNGHCLLNQVNQLPY-CVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI----CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSC-EKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSI--INNVFICNCSNVSYTGERCT---NKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            +++  C ++ C N   C +     I    C C++  F G+ C +   +C  +PC NG  C    N+  C+C   G+ G +C  +I  C    KC N GIC+   G   C+C  T Y G+ CE P   C    CLN G C  +Q     Y C C   GF G+ C   +  CP + C  NG C+   ++  C C   +TG  C + +       + C NGG C        CVC   + G  C E    C    C  G  C        C C      G  C     C    C  G +C    +N   IC C    + G  C    ++     N C++ G C    G F C C   GY G +C+  ++
Sbjct:   54 QHLDPCHRSPCLNAAACKSQVANSIPQYTCVCQRG-FRGQDCSLVD-ACATSPCANGARCTNWNNHYNCSCP-PGYQGKNCRNDIDECRKPGKCLNGGICMNTHGSFRCECL-TGYSGRTCEVPTQPCAPSQCLNGGTC--HQTGDHTYECAC-LPGFRGHNCEDNVDDCPGHKCMNNGICVDGVNTYNCQCPPEWTGQYCAEDVNECLMQPNACHNGGTCFNTIGGHTCVCVNGWTGDDCSENIDDCATAVCFNGATCHDRVASFFCECP-VGKTGLLCHLDDACVSNPCNEGAVCDTNPLNGRAICTCP-AGFVGGACNQDMDECSIGANPCEHFGKCVNTEGSFQCQCG-RGYTGPRCEIDIN 409          

HSP 5 Score: 80.8777 bits (198), Expect = 2.189e-14
Identity = 108/362 (29.83%), Postives = 148/362 (40.88%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFC--DIKRPSCDPNPCKN-GICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCE-TPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI----CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCE-KPKPCPVGYCLYGGKCR-MVNGMPRCNCTQTNYMGXX-XXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKV-GCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            C++NV  CP + C N G C +   T   C C   ++ G++C  D+      PN C N G C        C C   G+TG DC   I  C    C N   C  +     C+C      G LC     C  + C     C  N +N    C C   GF G  CN+ +       N C   G C+  + S  C C  G+TG +CE  I  C    C N   C+       C+C   +QGK CE     C    C+  G CR MVNG   C C Q  + G        +C    C+NG  C    N + C C+   + G  C + +  C  + C + G C      + CNC   GY G +C+ +++
Sbjct:  209 CEDNVDDCPGHKCMNNGICVDGVNT-YNCQCPP-EWTGQYCAEDVNECLMQPNACHNGGTCFNTIGGHTCVCV-NGWTGDDCSENIDDCATAVCFNGATCHDRVASFFCEC-PVGKTGLLCHLDDACVSNPCNEGAVCDTNPLNGRAICTC-PAGFVGGACNQDMDECSIGANPCEHFGKCVNTEGSFQCQCGRGYTGPRCEIDINECLSMPCQNDATCLDRIGEFTCICMPGYQGKYCEVDIDECESNPCVNDGICRDMVNGF-TCTC-QPGFTGTMCQIDIDECASTPCQNGAKCIDRPNGYECRCAE-GFEGRLCESNIDNCKPDPCHH-GTCVDGIASYTCNCE-PGYTGYRCENQLN 560          

HSP 6 Score: 79.337 bits (194), Expect = 6.528e-14
Identity = 100/360 (27.78%), Postives = 133/360 (36.94%), Query Frame = 1
Query: 2071 RACQENVKKCPK-NYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKN-GICQIVGNNRI-CNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRM--VNGMPRCNCTQTNYMGX--XXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            + C+ ++ +C K   C N G C N + +   C+C  T + G  C++    C P+ C N G C   G++   C C   GF G +CE  +  C  HKC NNGIC+       C C    + GQ C           +   CL+                            N C   G C        C C  G+TGD C + I  C+   C NG  C     S FC C     G  C     C    C  G  C    +NG   C C      G   +           CE+ G C      F C C    YTG RC   +  C    C+N   C    G+F C C + GY G+ C+  +D
Sbjct:  129 KNCRNDIDECRKPGKCLNGGICMNTHGS-FRCECL-TGYSGRTCEVPTQPCAPSQCLNGGTCHQTGDHTYECACL-PGFRGHNCEDNVDDCPGHKCMNNGICVDGVNTYNCQCPPE-WTGQYCAE---------DVNECLMQ--------------------------PNACHNGGTCFNTIGGHTCVCVNGWTGDDCSENIDDCATAVCFNGATCHDRVASFFCECPVGKTGLLCHLDDACVSNPCNEGAVCDTNPLNGRAICTCPAGFVGGACNQDMDECSIGANPCEHFGKCVNTEGSFQCQCGR-GYTGPRCEIDINECLSMPCQNDATCLDRIGEFTCIC-MPGYQGKYCEVDID 447          

HSP 7 Score: 74.7146 bits (182), Expect = 1.501e-12
Identity = 103/362 (28.45%), Postives = 149/362 (41.16%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCPLDFCLNN----GHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPK-PCPVGYCLYGGKC-RMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGK---FGCNCSLTGYGGEQCDQKVD 3114
            CQ ++ +C    CQN  +C +       C C +  F G  C+    +C P+PC +G C     +  CNC   G+TG+ CE  ++ C ++ CQN G C+       C C      G  CE      D C +N    G C  + +N+   CVC   GF G +C   I  C  N C   G C+  ++   C C EGF    C   +  C+ + C++ G C        C C   + GK+C+  +  C    C   G C   +NG   C C Q            +C    C N G C      F C C    Y+G  C   +  C  N C N  +C +H      + CNC   G+ G  C+  ++
Sbjct:  480 CQIDIDECASTPCQNGAKCID-RPNGYECRCAEG-FEGRLCESNIDNCKPDPCHHGTCVDGIASYTCNCE-PGYTGYRCENQLNECHSNPCQNGGKCVDLVNKYICQCQHGT-SGTNCEIN---FDDCASNPCDYGICK-DGINRY-ECVCKP-GFTGPQCKDEIDECQSNPCRNGGTCVDDENGFHCQCPEGFHDPYCYSQVDECASNPCLH-GTCRDDPNGYRCDCEPGWVGKNCDLDRNDCLPSPCQNAGTCFDQLNGF-TCKCRQGFRGNLCQVNINECASSPCLNQGTCVDGVASFTCLCE-PPYSGPTCAELLTPCSPNPCANHASC-VHTPDYLGYQCNCQ-PGWQGHLCNNDIN 826          

HSP 8 Score: 72.7886 bits (177), Expect = 6.110e-12
Identity = 83/268 (30.97%), Postives = 112/268 (41.79%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCD--------PNPCKNGIC-QIVGNNRICNCTGTGFTGFDCE--ISRCFNHKC--QNNGICILKQGIPECDCTKTVYEGQLCET--PKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI-CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI---CSKDKCINGGKCVVVDRSPF--CVCAKDFQGKSCEK--------PKPCPVGYCL 2793
            C+  V +C  + CQN G C ++    I C C      G  C+I    C         P    NG C   VG  R CNC   GFTG  CE  I+ C ++ C   N+  CI      +C C K  + G+ C++    C    C N G C L+  +   Y      G+ G  C + + C +  C   G+C +    A C C +GF G  C+      CS   C NGG C      PF  C C   ++GK CE+        P PCP+  C 
Sbjct: 1136 CEREVNECQSHPCQNGGTCIDLVGHYI-CSCPPGTL-GVLCEINEDDCATPSWPRGMPKCQNNGTCVDRVGGYR-CNCP-PGFTGERCEGDINECLSNPCNPSNSLDCIQLPNDYQCVC-KPGFTGRGCQSRFSVCESQPCKNGGVCSLSGSSPPGYSCTCQLGYAGSNCERSMNCKELPCYNGGSCTLTTRGARCTCIQGFGGPLCQHRSNDGCSSKPCHNGGLCTEETSYPFFHCQCTNGWKGKRCEQKTGSSAPLPSPCPIADCF 1398          

HSP 9 Score: 61.2326 bits (147), Expect = 1.901e-8
Identity = 81/302 (26.82%), Postives = 107/302 (35.43%), Query Frame = 1
Query: 2332 NHKCQNNGICILKQGIPECDCTKTVYEGQLCE-TPKCPLDFCLNNGHCLLNQVNQLPY--CVCNSTGFYGYRCN-KPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSK-DKCINGGKCVVVDRSPFCVCAKDFQGKSCEKP-KPCPVGYCLYGGKCRM-------------------------------------VNGMPRCNCT----QTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKV-GCPDNYCKNGGACEIHRGKFGCNCSLTGYG 3087
            +  C+N G+CI  +    C C +  Y G LC+    C    CLN   C     N +P   CVC   GF G  C+    C  + C     C   ++   C C  G+ G  C   I  C K  KC+NGG C+    S  C C   + G++CE P +PC    CL GG C                                       V+G+   NC      T     +           C NGG C        C C N  +TG+ C+  +  C    C NG  C      F C C +   G
Sbjct:   28 HRPCENGGMCIDSR----CLC-RPGYIGSLCQHLDPCHRSPCLNAAACKSQVANSIPQYTCVCQR-GFRGQDCSLVDACATSPCANGARCTNWNNHYNCSCPPGYQGKNCRNDIDECRKPGKCLNGGICMNTHGSFRCECLTGYSGRTCEVPTQPCAPSQCLNGGTCHQTGDHTYECACLPGFRGHNCEDNVDDCPGHKCMNNGICVDGVNTYNCQCPPEWTGQYCAEDVNECLMQPNACHNGGTCFNTIGGHTCVCVN-GWTGDDCSENIDDCATAVCFNGATCHDRVASFFCECPVGKTG 322          

HSP 10 Score: 55.8398 bits (133), Expect = 7.730e-7
Identity = 62/214 (28.97%), Postives = 86/214 (40.19%), Query Frame = 1
Query: 2500 YCVCNSTGFYGYRCNKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEK-PICSKDKCINGGKC--VVVDRSP--FCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGX--XXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGAC-EIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            Y V NS G      ++P      C   G C+     + C C  G+ G  C+    C +  C+N   C   V +  P   CVC + F+G+ C     C    C  G +C   N    C+C    Y GK  + +  +      C NGGIC   +  F C C    Y+G  C      C  + C NGG C +     + C C L G+ G  C+  VD
Sbjct:   14 YLVHNSEGLLCVDTHRP------CENGGMCI----DSRCLCRPGYIGSLCQHLDPCHRSPCLNAAACKSQVANSIPQYTCVCQRGFRGQDCSLVDACATSPCANGARCTNWNNHYNCSCP-PGYQGKNCRNDIDECRKPGKCLNGGICMNTHGSFRCECL-TGYSGRTCEVPTQPCAPSQCLNGGTCHQTGDHTYECAC-LPGFRGHNCEDNVD 214          
BLAST of notch-1 vs. Ensembl Xenopus
Match: emid1 (EMI domain containing 1 [Source:Xenbase;Acc:XB-GENE-5872275])

HSP 1 Score: 120.939 bits (302), Expect = 1.729e-26
Identity = 139/506 (27.47%), Postives = 212/506 (41.90%), Query Frame = 1
Query: 2071 RACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKN-GICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCE--TPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCE--KPICSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCT-NKVGCPDNYCKNGGACEIHRGKFGCNC-----SLTGYGGEQCDQKVDGVM---CDYK------------------EPGY----------------AITAFKPPMVSSGIVTSMG--FQTFVKTGTLFCYETADDKYWLIKLVNGRLVADINGISFNMKTV-----VSDGRYHFLKVSRDETNFV-ISLDH 3408
            + C+ NV +C  N CQN+  C +  + +  C C    F G  C+I    C   PC+N G C    +   C C   G+TG +CE  I  C +  CQN   C    G   CDC    Y+G+ C+    +C    C N G C+ +++N+   C C++TGF G RC   I  C  N C  NG C+ R +   C C +G++G  CE     C ++ C+NGG C+ +    +     +F   S  +           G  CR   G    NC+             +C    C NGG C+ + N F+CNC++  YTG  C+ N   C D+ CKNG +CE     + C C       T +GG+ C   + G +   C                     +PG+                    +  P+ +    ++M   F+T +    L  Y   +D +  +++ NG L   + G       V     V+DG +H ++V     +F+ ISL H
Sbjct:  151 QECEVNVNECASNPCQNEALCVDKVD-RYMCFCVPG-FQGHHCEIDINECASRPCQNNGTCMNQLDQYECAC-ANGYTGINCEMEIDECQSVPCQNGATCRDHIGYFTCDCPAG-YDGEQCQHDIDECQSQPCQNGGQCM-DEINRF-RCDCSNTGFVGGRCEVEILECDSNPCQNNGTCMERVNGYECLCWKGYSGIHCEIDDNECFEEPCVNGGLCLELSNQSYYGTEPEFNKFSYSQAA---------GYLCRCQQGFTGPNCS---------VNIDECESWPCLNGGTCTDLINGFLCNCAS-GYTGFDCSINIDECKDSPCKNGASCEDGVADYSCICPPAAQDGTVWGGKNCSVMLIGCLEHSCQNAAECIPLYTGQSHSYTCKCQPGFVGNNCSTPTTFSFLSQGYLMYDSPLSNESYQSNMSVRFRTTLPDMVLM-YRGDEDSFLALEIYNGFLHMRLKGNGRLFPLVIDDYKVNDGHWHNVEVDLLSNSFLKISLFH 630          

HSP 2 Score: 94.3597 bits (233), Expect = 1.981e-18
Identity = 99/314 (31.53%), Postives = 132/314 (42.04%), Query Frame = 1
Query: 2215 SCDPNPCKNG-ICQIVGNNRICNCTGT--GFTGFDCE--ISRCFNHKCQNNGICILKQGIP--ECDCTKTVYEGQLCETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICP--QNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCV-VVDRSPFCVCAKDFQGKSCE-KPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXY-CENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKV 3111
            +C  +PC NG  CQ   +   C C      FTG  C      C   +C +   C    G P  +C C   +     C+   CP      N  C + + + +  C C S G+ G  CN  + P  QN C  N  CL   DS  C C+ GFTG +CE  +  C+ + C N   CV  VDR   C C   FQG  CE     C    C   G C        C C    Y G  CE      +   C+NG  C      F C+C    Y GE+C + +  C    C+NGG C     +F C+CS TG+ G +C+ ++
Sbjct:    7 TCVSSPCLNGGTCQETASGFTCLCPAEPLAFTGTTCGDLYDACAIDRCPSTHSCQSTPGHPHFQCVCQPGLNCTNECQRNSCPF----QNFQCTVGEDSFM--CKCQS-GYGGVDCNFEVSPCFQNPCQNNATCLAEGDSFRCVCEPGFTGQECEVNVNECASNPCQNEALCVDKVDRY-MCFCVPGFQGHHCEIDINECASRPCQNNGTCMNQLDQYECACA-NGYTGINCEMEIDECQSVPCQNGATCRDHIGYFTCDCP-AGYDGEQCQHDIDECQSQPCQNGGQCMDEINRFRCDCSNTGFVGGRCEVEI 310          

HSP 3 Score: 77.0258 bits (188), Expect = 4.124e-13
Identity = 95/378 (25.13%), Postives = 155/378 (41.01%), Query Frame = 1
Query: 1576 AVNVFSSEDWMTLLVNSNSIILAYSLPPNEGVHTIEMTRGGILIQDNTWHRVIINLNKPKEI---LYIHIDDVESLTNEIKLKNSKKELAEMNFISLSLGGISDNSQYTQFYNLLRKKNPEVSKLFSGPDELKFIGCLGDILV--INSSYSGNLIQKPNVNSFPKES----LFCRACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGICQIVGNNRICNCTGTGFTGFDCEIS--RCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCPLD-----FCLNNGHCLLNQVNQLPYCVCNSTGFYGYRC--NKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEK 2655
            AV + SS++  ++L+      L   L     V  +++  G I + D  WHRV+I + +  ++       +DD          K  + E   +NF+  ++  +                      L  G     + GCLGD+ +  I   ++ +++  P  + F ++S    L CR        C ++ C + G C ++  +  +C C+   + G  C+I    C  +PC +G C  +  +  C+C   G+T  +CEI+   C +H+C N G C+       C C    Y G  C+ P  P        C N G C  N       C C   GF G RC  N   C  N C   G C    ++  C C+  F+G +CEK
Sbjct: 1029 AVLLQSSKNVDSVLIEIQGGYLFVDLQSGNNVDGVQL-NGTIDVADAIWHRVVITMERATKVNSHWTFQLDDSVQ-------KKFQWEGDNLNFMRNNISIV----------------------LAEG-----YTGCLGDVSIGGIYLPFTDHVL--PQQDQFIRKSDALELGCRG----ADVCSESPCLHGGTCQDLFNS-FSCTCR-IGWNGHRCEINIDDCKSSPCLHGFCIDLEADYQCSCEA-GYTSRNCEININDCQHHQCLNGGTCVDGVNNYTCKCPAN-YAGTFCQWPFPPEQCNKNITCFNGGRC--NSGIWGANCTCRP-GFSGRRCEINVNDCESNPCLNGGTCQDSVNTFKCICNSSFSGVRCEK 1358          

HSP 4 Score: 57.3806 bits (137), Expect = 3.783e-7
Identity = 66/247 (26.72%), Postives = 102/247 (41.30%), Query Frame = 1
Query: 2551 ICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCE-KPKPCPVGYCLYGGKCRMVNGMPRCNCT-QTNYMGXXXXX----XXXXXXXYCENGGICSIINNVFICNCS-NVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVDGVMCDYKEPGYAITAFKPPMVSSGIVTSMGFQTFVKTGTLFCYETADDK 3261
            +C ++ C   G C    +S  C C  G+ G +CE  I  C    C++G  C+ ++    C C   +  ++CE     C    CL GG C  V+G+    C    NY G  C+      +      C NGG C+  + ++  NC+    ++G RC   V  C  N C NGG C+     F C           C+    GV C+  +   A + F  P+V   +  + G    +  G +F   TA  +
Sbjct: 1170 VCSESPCLHGGTCQDLFNSFSCTCRIGWNGHRCEINIDDCKSSPCLHG-FCIDLEADYQCSCEAGYTSRNCEININDCQHHQCLNGGTC--VDGVNNYTCKCPANYAGTFCQWPFPPEQCNKNITCFNGGRCN--SGIWGANCTCRPGFSGRRCEINVNDCESNPCLNGGTCQDSVNTFKC----------ICNSSFSGVRCEKSD---AASMFPFPLVGVAVPVTCGVLLLLVIGVIFMVLTARKR 1398          
BLAST of notch-1 vs. Ensembl Xenopus
Match: emid1 (EMI domain containing 1 [Source:Xenbase;Acc:XB-GENE-5872275])

HSP 1 Score: 120.553 bits (301), Expect = 2.157e-26
Identity = 139/506 (27.47%), Postives = 212/506 (41.90%), Query Frame = 1
Query: 2071 RACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKN-GICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCE--TPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCE--KPICSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCT-NKVGCPDNYCKNGGACEIHRGKFGCNC-----SLTGYGGEQCDQKVDGVM---CDYK------------------EPGY----------------AITAFKPPMVSSGIVTSMG--FQTFVKTGTLFCYETADDKYWLIKLVNGRLVADINGISFNMKTV-----VSDGRYHFLKVSRDETNFV-ISLDH 3408
            + C+ NV +C  N CQN+  C +  + +  C C    F G  C+I    C   PC+N G C    +   C C   G+TG +CE  I  C +  CQN   C    G   CDC    Y+G+ C+    +C    C N G C+ +++N+   C C++TGF G RC   I  C  N C  NG C+ R +   C C +G++G  CE     C ++ C+NGG C+ +    +     +F   S  +           G  CR   G    NC+             +C    C NGG C+ + N F+CNC++  YTG  C+ N   C D+ CKNG +CE     + C C       T +GG+ C   + G +   C                     +PG+                    +  P+ +    ++M   F+T +    L  Y   +D +  +++ NG L   + G       V     V+DG +H ++V     +F+ ISL H
Sbjct:  175 QECEVNVNECASNPCQNEALCVDKVD-RYMCFCVPG-FQGHHCEIDINECASRPCQNNGTCMNQLDQYECAC-ANGYTGINCEMEIDECQSVPCQNGATCRDHIGYFTCDCPAG-YDGEQCQHDIDECQSQPCQNGGQCM-DEINRF-RCDCSNTGFVGGRCEVEILECDSNPCQNNGTCMERVNGYECLCWKGYSGIHCEIDDNECFEEPCVNGGLCLELSNQSYYGTEPEFNKFSYSQAA---------GYLCRCQQGFTGPNCS---------VNIDECESWPCLNGGTCTDLINGFLCNCAS-GYTGFDCSINIDECKDSPCKNGASCEDGVADYSCICPPAAQDGTVWGGKNCSVMLIGCLEHSCQNAAECIPLYTGQSHSYTCKCQPGFVGNNCSTPTTFSFLSQGYLMYDSPLSNESYQSNMSVRFRTTLPDMVLM-YRGDEDSFLALEIYNGFLHMRLKGNGRLFPLVIDDYKVNDGHWHNVEVDLLSNSFLKISLFH 654          

HSP 2 Score: 94.3597 bits (233), Expect = 2.115e-18
Identity = 99/314 (31.53%), Postives = 132/314 (42.04%), Query Frame = 1
Query: 2215 SCDPNPCKNG-ICQIVGNNRICNCTGT--GFTGFDCE--ISRCFNHKCQNNGICILKQGIP--ECDCTKTVYEGQLCETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICP--QNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCV-VVDRSPFCVCAKDFQGKSCE-KPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXY-CENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKV 3111
            +C  +PC NG  CQ   +   C C      FTG  C      C   +C +   C    G P  +C C   +     C+   CP      N  C + + + +  C C S G+ G  CN  + P  QN C  N  CL   DS  C C+ GFTG +CE  +  C+ + C N   CV  VDR   C C   FQG  CE     C    C   G C        C C    Y G  CE      +   C+NG  C      F C+C    Y GE+C + +  C    C+NGG C     +F C+CS TG+ G +C+ ++
Sbjct:   31 TCVSSPCLNGGTCQETASGFTCLCPAEPLAFTGTTCGDLYDACAIDRCPSTHSCQSTPGHPHFQCVCQPGLNCTNECQRNSCPF----QNFQCTVGEDSFM--CKCQS-GYGGVDCNFEVSPCFQNPCQNNATCLAEGDSFRCVCEPGFTGQECEVNVNECASNPCQNEALCVDKVDRY-MCFCVPGFQGHHCEIDINECASRPCQNNGTCMNQLDQYECACA-NGYTGINCEMEIDECQSVPCQNGATCRDHIGYFTCDCP-AGYDGEQCQHDIDECQSQPCQNGGQCMDEINRFRCDCSNTGFVGGRCEVEI 334          

HSP 3 Score: 76.6406 bits (187), Expect = 4.250e-13
Identity = 95/378 (25.13%), Postives = 155/378 (41.01%), Query Frame = 1
Query: 1576 AVNVFSSEDWMTLLVNSNSIILAYSLPPNEGVHTIEMTRGGILIQDNTWHRVIINLNKPKEI---LYIHIDDVESLTNEIKLKNSKKELAEMNFISLSLGGISDNSQYTQFYNLLRKKNPEVSKLFSGPDELKFIGCLGDILV--INSSYSGNLIQKPNVNSFPKES----LFCRACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGICQIVGNNRICNCTGTGFTGFDCEIS--RCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCPLD-----FCLNNGHCLLNQVNQLPYCVCNSTGFYGYRC--NKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEK 2655
            AV + SS++  ++L+      L   L     V  +++  G I + D  WHRV+I + +  ++       +DD          K  + E   +NF+  ++  +                      L  G     + GCLGD+ +  I   ++ +++  P  + F ++S    L CR        C ++ C + G C ++  +  +C C+   + G  C+I    C  +PC +G C  +  +  C+C   G+T  +CEI+   C +H+C N G C+       C C    Y G  C+ P  P        C N G C  N       C C   GF G RC  N   C  N C   G C    ++  C C+  F+G +CEK
Sbjct: 1053 AVLLQSSKNVDSVLIEIQGGYLFVDLQSGNNVDGVQL-NGTIDVADAIWHRVVITMERATKVNSHWTFQLDDSVQ-------KKFQWEGDNLNFMRNNISIV----------------------LAEG-----YTGCLGDVSIGGIYLPFTDHVL--PQQDQFIRKSDALELGCRG----ADVCSESPCLHGGTCQDLFNS-FSCTCR-IGWNGHRCEINIDDCKSSPCLHGFCIDLEADYQCSCEA-GYTSRNCEININDCQHHQCLNGGTCVDGVNNYTCKCPAN-YAGTFCQWPFPPEQCNKNITCFNGGRC--NSGIWGANCTCRP-GFSGRRCEINVNDCESNPCLNGGTCQDSVNTFKCICNSSFSGVRCEK 1382          

HSP 4 Score: 56.9954 bits (136), Expect = 4.270e-7
Identity = 66/247 (26.72%), Postives = 102/247 (41.30%), Query Frame = 1
Query: 2551 ICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCE-KPKPCPVGYCLYGGKCRMVNGMPRCNCT-QTNYMGXXXXX----XXXXXXXYCENGGICSIINNVFICNCS-NVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVDGVMCDYKEPGYAITAFKPPMVSSGIVTSMGFQTFVKTGTLFCYETADDK 3261
            +C ++ C   G C    +S  C C  G+ G +CE  I  C    C++G  C+ ++    C C   +  ++CE     C    CL GG C  V+G+    C    NY G  C+      +      C NGG C+  + ++  NC+    ++G RC   V  C  N C NGG C+     F C           C+    GV C+  +   A + F  P+V   +  + G    +  G +F   TA  +
Sbjct: 1194 VCSESPCLHGGTCQDLFNSFSCTCRIGWNGHRCEINIDDCKSSPCLHG-FCIDLEADYQCSCEAGYTSRNCEININDCQHHQCLNGGTC--VDGVNNYTCKCPANYAGTFCQWPFPPEQCNKNITCFNGGRCN--SGIWGANCTCRPGFSGRRCEINVNDCESNPCLNGGTCQDSVNTFKC----------ICNSSFSGVRCEKSD---AASMFPFPLVGVAVPVTCGVLLLLVIGVIFMVLTARKR 1422          
BLAST of notch-1 vs. Ensembl Xenopus
Match: emid1 (EMI domain containing 1 [Source:Xenbase;Acc:XB-GENE-5872275])

HSP 1 Score: 120.168 bits (300), Expect = 2.596e-26
Identity = 138/506 (27.27%), Postives = 212/506 (41.90%), Query Frame = 1
Query: 2071 RACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKN-GICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCE--TPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCE--KPICSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNC-----SLTGYGGEQCDQKVDGVM---CDYK------------------EPGY----------------AITAFKPPMVSSGIVTSMG--FQTFVKTGTLFCYETADDKYWLIKLVNGRLVADINGISFNMKTV-----VSDGRYHFLKVSRDETNFV-ISLDH 3408
            + C+ NV +C  N CQN+  C +  + +  C C    F G  C+I    C   PC+N G C    +   C C   G+TG +CE  I  C +  CQN   C    G   CDC    Y+G+ C+    +C    C N G C+ +++N+   C C++TGF G RC   I  C  N C  NG C+ R +   C C +G++G  CE     C ++ C+NGG C+ +    +     +F   S  +           G  CR   G    NC+             +C    C NGG C+ + N F+CNC++  YTG  C+  +  C D+ CKNG +CE     + C C       T +GG+ C   + G +   C                     +PG+                    +  P+ +    ++M   F+T +    L  Y   +D +  +++ NG L   + G       V     V+DG +H ++V     +F+ ISL H
Sbjct:  175 QECEVNVNECASNPCQNEALCVDKVD-RYMCFCVPG-FQGHHCEIDINECASRPCQNNGTCMNQLDQYECAC-ANGYTGINCEMEIDECQSVPCQNGATCRDHIGYFTCDCPAG-YDGEQCQHDIDECQSQPCQNGGQCM-DEINRF-RCDCSNTGFVGGRCEVEILECDSNPCQNNGTCMERVNGYECLCWKGYSGIHCEIDDNECFEEPCVNGGLCLELSNQSYYGTEPEFNKFSYSQAA---------GYLCRCQQGFTGPNCS---------VNIDECESWPCLNGGTCTDLINGFLCNCAS-GYTGFDCSINIDECKDSPCKNGASCEDGVADYSCICPPAAQDGTVWGGKNCSVMLIGCLEHSCQNAAECIPLYTGQSHSYTCKCQPGFVGNNCSTPTTFSFLSQGYLMYDSPLSNESYQSNMSVRFRTTLPDMVLM-YRGDEDSFLALEIYNGFLHMRLKGNGRLFPLVIDDYKVNDGHWHNVEVDLLSNSFLKISLFH 654          

HSP 2 Score: 94.3597 bits (233), Expect = 2.114e-18
Identity = 99/314 (31.53%), Postives = 132/314 (42.04%), Query Frame = 1
Query: 2215 SCDPNPCKNG-ICQIVGNNRICNCTGT--GFTGFDCE--ISRCFNHKCQNNGICILKQGIP--ECDCTKTVYEGQLCETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICP--QNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCV-VVDRSPFCVCAKDFQGKSCE-KPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXY-CENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKV 3111
            +C  +PC NG  CQ   +   C C      FTG  C      C   +C +   C    G P  +C C   +     C+   CP      N  C + + + +  C C S G+ G  CN  + P  QN C  N  CL   DS  C C+ GFTG +CE  +  C+ + C N   CV  VDR   C C   FQG  CE     C    C   G C        C C    Y G  CE      +   C+NG  C      F C+C    Y GE+C + +  C    C+NGG C     +F C+CS TG+ G +C+ ++
Sbjct:   31 TCVSSPCLNGGTCQETASGFTCLCPAEPLAFTGTTCGDLYDACAIDRCPSTHSCQSTPGHPHFQCVCQPGLNCTNECQRNSCPF----QNFQCTVGEDSFM--CKCQS-GYGGVDCNFEVSPCFQNPCQNNATCLAEGDSFRCVCEPGFTGQECEVNVNECASNPCQNEALCVDKVDRY-MCFCVPGFQGHHCEIDINECASRPCQNNGTCMNQLDQYECACA-NGYTGINCEMEIDECQSVPCQNGATCRDHIGYFTCDCP-AGYDGEQCQHDIDECQSQPCQNGGQCMDEINRFRCDCSNTGFVGGRCEVEI 334          

HSP 3 Score: 85.1149 bits (209), Expect = 1.296e-15
Identity = 102/411 (24.82%), Postives = 166/411 (40.39%), Query Frame = 1
Query: 1576 AVNVFSSEDWMTLLVNSNSIILAYSLPPNEGVHTIEMTRGGILIQDNTWHRVIINLNKPKEI---LYIHIDDVESLTNEIKLKNSKKELAEMNFISLSLGGISDNSQYTQFYNLLRKKNPEVSKLFSGPDELKFIGCLGDILV--INSSYSGNLIQKPNVNSFPKES----LFCRACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGICQIVGNNRICNCTGTGFTGFDCEIS--RCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPK 2769
            AV + SS++  ++L+      L   L     V  +++  G I + D  WHRV+I + +  ++       +DD          K  + E   +NF+  ++  +                      L  G     + GCLGD+ +  I   ++ +++  P  + F ++S    L CR        C ++ C + G C ++  +  +C C+   + G  C+I    C  +PC +G C  +  +  C+C   G+T  +CEI+   C +H+C N G C+       C C    Y G  C+ P  P             Q N+      N T F G RCN  I   N                C C  GF+G +CE  +  C  + C+NGG C     +  C+C   F G  CEKP+
Sbjct: 1053 AVLLQSSKNVDSVLIEIQGGYLFVDLQSGNNVDGVQL-NGTIDVADAIWHRVVITMERATKVNSHWTFQLDDSVQ-------KKFQWEGDNLNFMRNNISIV----------------------LAEG-----YTGCLGDVSIGGIYLPFTDHVL--PQQDQFIRKSDALELGCRG----ADVCSESPCLHGGTCQDLFNS-FSCTCR-IGWNGHRCEINIDDCKSSPCLHGFCIDLEADYQCSCEA-GYTSRNCEININDCQHHQCLNGGTCVDGVNNYTCKCPAN-YAGTFCQWPFPP------------EQCNK------NITCFNGGRCNSGIWGAN----------------CTCRPGFSGRRCEINVNDCESNPCLNGGTCQDSVNTFKCICNSSFSGVRCEKPR 1384          

HSP 4 Score: 52.7582 bits (125), Expect = 9.317e-6
Identity = 62/191 (32.46%), Postives = 87/191 (45.55%), Query Frame = 1
Query: 2452 CLNNGHC--LLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVG-----YCLYGGKCRMVNGMPRCNCT-QTNYMGXX-XXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERC 2985
            CL+ G C  L N  +    C C   G+ G+RC   I  C  + C  +G C+  +    C C+ G+T   CE  I  C   +C+NGG CV    +  C C  ++ G  C+ P P P        C  GG+C   +G+   NCT +  + G++       C    C NGG C    N F C C N S++G RC
Sbjct: 1200 CLHGGTCQDLFNSFS----CTCR-IGWNGHRCEINIDDCKSSPCL-HGFCIDLEADYQCSCEAGYTSRNCEININDCQHHQCLNGGTCVDGVNNYTCKCPANYAGTFCQWPFP-PEQCNKNITCFNGGRCN--SGIWGANCTCRPGFSGRRCEINVNDCESNPCLNGGTCQDSVNTFKCIC-NSSFSGVRC 1380          

HSP 5 Score: 52.7582 bits (125), Expect = 9.718e-6
Identity = 65/229 (28.38%), Postives = 95/229 (41.48%), Query Frame = 1
Query: 2551 ICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCE-KPKPCPVGYCLYGGKCRMVNGMPRCNCT-QTNYMGXXXXX----XXXXXXXYCENGGICSIINNVFICNCS-NVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVDGVMCDYKEPGYAITAFKPPMVSSGIVTSMGF 3207
            +C ++ C   G C    +S  C C  G+ G +CE  I  C    C++G  C+ ++    C C   +  ++CE     C    CL GG C  V+G+    C    NY G  C+      +      C NGG C+  + ++  NC+    ++G RC   V  C  N C NGG C+     F C           C+    GV C+  +P     A    +V S I T M F
Sbjct: 1194 VCSESPCLHGGTCQDLFNSFSCTCRIGWNGHRCEINIDDCKSSPCLHG-FCIDLEADYQCSCEAGYTSRNCEININDCQHHQCLNGGTC--VDGVNNYTCKCPANYAGTFCQWPFPPEQCNKNITCFNGGRCN--SGIWGANCTCRPGFSGRRCEINVNDCESNPCLNGGTCQDSVNTFKC----------ICNSSFSGVRCE--KPRLHREAKASTLVGSAIGTGMLF 1405          
BLAST of notch-1 vs. Ensembl Xenopus
Match: notch1 (notch 1 receptor [Source:NCBI gene;Acc:100037842])

HSP 1 Score: 114.005 bits (284), Expect = 2.670e-24
Identity = 109/369 (29.54%), Postives = 161/369 (43.63%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETK-IACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRC--NKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEK-PKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMG-----------XXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            C+  +  C  + C+N GRC    + +  +C+C    + G+ C+I    C   PC+NG +CQ    +  CNC   G+ G  CE  I  C  + C N G C     +  C+C    + G  CE    +C  + C N  +C  + VN    C C   GF G  C  N P C ++ C   G C+   ++  C C  GFTG+ C+  I  C    C+NGG C     +  C C + + G +C+   + C    C  GGKC   N   RC C ++ + G              ++        C N G+C    N   C C    YTG  C  +V  C  N C+NG  C  + G + C C + GY G  C ++++
Sbjct:  515 CEAVLAPCSGSPCKNGGRCKESEDYETFSCECPPG-WQGQTCEIDMNECVNRPCRNGAMCQNTNGSYKCNCK-PGYAGRHCETDIDDCQPNPCHNGGSCSDGINMFFCNCPAG-FRGPKCEEDINECASNPCKNGANCT-DCVNSY-TCTC-QPGFSGIHCENNTPDCTESSCFNGGTCIDGINTFSCQCPPGFTGNYCQHDINECDSKPCLNGGTCQDSYGAYKCTCPQGYTGLNCQNLVRWCDSSPCKNGGKCWQTNNFYRCEC-KSGWTGVYCDVPSVSCEVAAKQQGVDIAHLCRNSGMCVDTGNTHFCRCQ-AGYTGSYCEEQVDECSPNPCQNGATCTDYLGGYSCEC-VAGYHGVNCSEEIN 874          

HSP 2 Score: 82.4185 bits (202), Expect = 1.002e-14
Identity = 108/387 (27.91%), Postives = 151/387 (39.02%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYN-INETKIACDCKKTQ------------------------FYGEFCDIKRPSCDPNPCKNGI-CQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCT-KTVYEGQLCETPKCPLDFCLN-----NGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCE--KPICSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINN--VFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            C+ N+ +C  N C + G+C + INE    C   K                          F G  C      C   PCKNG  C    N+  C CT  GFTG  CE  I+ C    C   G C  K GI    C  +  Y G+LC+     ++ CL+     NG    +++N    CVC   G++ + C   +  C  N C  +G C    +   C CD G++G  C+     C  + C+NGG C  +  +  C C   F+         C    CL  G C       +CNC               C    C+NGG C    +   F C C    + G+ C   +  C +  C+NG  C+   G + CNC   GY G  C+  +D
Sbjct:  224 CETNIDECASNPCLHNGKCVDKINEFHCECPTGKGAARHPRPGAVFGYAQFQARCRHRSCFNGNLCQHDVDECASTPCKNGAKCLDGPNSYTCQCT-EGFTGRHCEQDINECIPDPCHY-GTC--KDGIATFTCLCRPGYTGRLCDND---INECLSHNPCRNGGTCKDKINGF-TCVC-PDGYHDHMCLSEVNECNSNPCI-HGTCHDGINGYKCDCDAGWSGSNCDVNNNECESNPCMNGGTCKDMTGAYICTCRAGFRPNCQTNINECASNPCLNRGTCIDDVAGYKCNCMLPYTGAICEAVLAPCSGSPCKNGGRCKESEDYETFSCECP-PGWQGQTCEIDMNECVNRPCRNGAMCQNTNGSYKCNCK-PGYAGRHCETDID 598          

HSP 3 Score: 81.2629 bits (199), Expect = 2.119e-14
Identity = 110/387 (28.42%), Postives = 150/387 (38.76%), Query Frame = 1
Query: 2071 RACQENVKKCPKNYCQNKGRCYN-INETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGI-CQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPY-CVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKP-----ICSKDK-------CINGGKCVVVDRSPFCVCAKDFQGKSCEKP-KPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVGCPDNY--------CKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVDGVMCDYKEP 3141
            R C+ ++  C  N C N G C + IN     C+C    F G  C+     C  NPCKNG  C    N+  C C   GF+G  CE     C    C N G CI       C C    + G  C+    +C    CLN G C   Q +   Y C C   G+ G  C   +  C  + C   G C   ++   C C  G+TG  C+ P     + +K +       C N G CV    + FC C   + G  CE+    C    C  G  C    G   C C    +     E+  +C    C NGG C  + N + C+C   +       N   C   Y        C N G C    G + C C   G+ GE+C+  V+  + +  +P
Sbjct:  591 RHCETDIDDCQPNPCHNGGSCSDGIN--MFFCNC-PAGFRGPKCEEDINECASNPCKNGANCTDCVNSYTCTCQ-PGFSGIHCENNTPDCTESSCFNGGTCIDGINTFSCQCPPG-FTGNYCQHDINECDSKPCLNGGTC---QDSYGAYKCTC-PQGYTGLNCQNLVRWCDSSPCKNGGKCWQTNNFYRCECKSGWTGVYCDVPSVSCEVAAKQQGVDIAHLCRNSGMCVDTGNTHFCRCQAGYTGSYCEEQVDECSPNPCQNGATCTDYLGGYSCECVAGYHGVNCSEEINECLSHPCHNGGTCIDLINTYKCSCPRGTQGVHCEINVDDCTPFYDSVSLEPKCFNNGKCIDRVGGYNCICP-PGFVGERCEGDVNECLSNPCDP 967          

HSP 4 Score: 80.8777 bits (198), Expect = 2.750e-14
Identity = 90/321 (28.04%), Postives = 128/321 (39.88%), Query Frame = 1
Query: 2107 NYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDC--EISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCE---------------TPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNG--NCLVRDDSAVCYCDEGFTGDKCEKPI-------------------------------------------CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKP--KPCPVGYCLYGGKCRMVNGMP--RCNCTQTNYMG 2862
            + C+N G C +   T   C C+   + G +C+ +   C PNPC+NG  C        C C   G+ G +C  EI+ C +H C N G CI      +C C +   +G  CE                PKC      NNG C+ ++V     C+C   GF G RC   +  C  N C   G  NC+   +   C C +GFTG +C+  +                                           C   +C NGG C+ V +S  CVC++ + G +C+ P   PC    C  GG C+     P  +C C  TN+ G
Sbjct:  803 HLCRNSGMCVDTGNTHF-CRCQ-AGYTGSYCEEQVDECSPNPCQNGATCTDYLGGYSCECVA-GYHGVNCSEEINECLSHPCHNGGTCIDLINTYKCSCPRGT-QGVHCEINVDDCTPFYDSVSLEPKC-----FNNGKCI-DRVGGY-NCIC-PPGFVGERCEGDVNECLSNPCDPRGTQNCIQLVNDYRCECRQGFTGRRCDSVVDGCKGLPCRNGGTCAVASNTERGFICKCPPGFDGATCEYDARTCGNLRCQNGGTCISVLKSSKCVCSEGYTGATCQYPVVSPCASRPCYNGGTCQFSPEEPFFQCFCP-TNFNG 1110          

HSP 5 Score: 68.1662 bits (165), Expect = 2.046e-10
Identity = 93/333 (27.93%), Postives = 138/333 (41.44%), Query Frame = 1
Query: 2200 DIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCEI--SRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCET--PKCPLDFCLNNGHCLLNQVNQLPYCVC--------------------------NSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGYCLYGGKCR-------MVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERC-TNKVGCPDNYCKNGGACEIHRGKFGCNC 3069
            D+   S   NPC++G  C     +  CNC   G+ G  CEI  + C ++ CQN+  C+ + G  +C C    YEG  CET   +C  + CL+NG C+ +++N+  +C C                          + + F G  C   +  C    C     CL   +S  C C EGFTG  CE+ I  C  D C + G C     +  C+C   + G+ C+      +  CL    CR        +NG   C C    +      +  +C    C + G C    N + C+C +  ++G  C  N   C  N C NGG C+   G + C C
Sbjct:  149 DVDECSLGANPCEHGGRCTNTLGSFQCNCP-QGYAGPRCEIDVNECLSNPCQNDATCLDQIGEFQCICMPG-YEGLYCETNIDECASNPCLHNGKCV-DKINEF-HCECPTGKGAARHPRPGAVFGYAQFQARCRHRSCFNGNLCQHDVDECASTPCKNGAKCLDGPNSYTCQCTEGFTGRHCEQDINECIPDPC-HYGTCKDGIATFTCLCRPGYTGRLCDN----DINECLSHNPCRNGGTCKDKINGF-TCVCPDGYHDHMCLSEVNECNSNPCIH-GTCHDGINGYKCDC-DAGWSGSNCDVNNNECESNPCMNGGTCKDMTGAYICTC 469          

HSP 6 Score: 60.8474 bits (146), Expect = 3.454e-8
Identity = 111/441 (25.17%), Postives = 163/441 (36.96%), Query Frame = 1
Query: 2044 SFPKESLFCRACQENVKKCP--KNYCQNKGRCYNIN----------------------------ETKIACDCKKTQFY--------GEFCDIKRPSCDPNPCKNGI---CQIVGNNRICNCTGTGFTGFDC--EISRCF--NHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEG---------------------------FTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEK------PKPCPVGYCLYGGKCRMVNGMPRCNCT-QTNYMGXXXXXXXXXXXXY--CENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCD 3102
            + P+ S   + C E+V +C    N CQN G C+N                               +   C  +   F+        G  C +   +C  NPC  G       V    IC C   G+TG  C  ++  C    + C++ G C    G  +C+C +  Y G  CE    +C  + C N+  C L+Q+ +   C+C   G+ G  C   I  C  N C  NG C+ + +   C C  G                           F G+ C+  +  C+   C NG KC+    S  C C + F G+ CE+      P PC  G C         +G+    C  +  Y G+ C+        +  C NGG C    N F C C +  Y    C ++V  C  N C + G C      + C+C   G+ G  CD
Sbjct:   18 NHPQPSPLGQYCTEDVDECQLMPNACQNGGTCHNTYGGYNCVCVNGWTGEDCSENIDDCANAACHSGATCHDRVASFFCECPHGRTGLLCHLDN-ACISNPCNEGSNCDTNPVNGKAICTCP-PGYTGPACNNDVDECSLGANPCEHGGRCTNTLGSFQCNCPQG-YAGPRCEIDVNECLSNPCQNDATC-LDQIGEF-QCIC-MPGYEGLYCETNIDECASNPCLHNGKCVDKINEFHCECPTGKGAARHPRPGAVFGYAQFQARCRHRSCFNGNLCQHDVDECASTPCKNGAKCLDGPNSYTCQCTEGFTGRHCEQDINECIPDPCHYGTC--------KDGIATFTCLCRPGYTGRLCDNDINECLSHNPCRNGGTCKDKINGFTCVCPD-GYHDHMCLSEVNECNSNPCIH-GTCHDGINGYKCDCD-AGWSGSNCD 441          
BLAST of notch-1 vs. Ensembl Xenopus
Match: notch1 (notch 1 receptor [Source:NCBI gene;Acc:100037842])

HSP 1 Score: 113.62 bits (283), Expect = 3.679e-24
Identity = 109/369 (29.54%), Postives = 161/369 (43.63%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETK-IACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRC--NKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEK-PKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMG-----------XXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            C+  +  C  + C+N GRC    + +  +C+C    + G+ C+I    C   PC+NG +CQ    +  CNC   G+ G  CE  I  C  + C N G C     +  C+C    + G  CE    +C  + C N  +C  + VN    C C   GF G  C  N P C ++ C   G C+   ++  C C  GFTG+ C+  I  C    C+NGG C     +  C C + + G +C+   + C    C  GGKC   N   RC C ++ + G              ++        C N G+C    N   C C    YTG  C  +V  C  N C+NG  C  + G + C C + GY G  C ++++
Sbjct:  725 CEAVLAPCSGSPCKNGGRCKESEDYETFSCECPPG-WQGQTCEIDMNECVNRPCRNGAMCQNTNGSYKCNCK-PGYAGRHCETDIDDCQPNPCHNGGSCSDGINMFFCNCPAG-FRGPKCEEDINECASNPCKNGANCT-DCVNSY-TCTC-QPGFSGIHCENNTPDCTESSCFNGGTCIDGINTFSCQCPPGFTGNYCQHDINECDSKPCLNGGTCQDSYGAYKCTCPQGYTGLNCQNLVRWCDSSPCKNGGKCWQTNNFYRCEC-KSGWTGVYCDVPSVSCEVAAKQQGVDIAHLCRNSGMCVDTGNTHFCRCQ-AGYTGSYCEEQVDECSPNPCQNGATCTDYLGGYSCEC-VAGYHGVNCSEEIN 1084          

HSP 2 Score: 87.0409 bits (214), Expect = 3.796e-16
Identity = 106/366 (28.96%), Postives = 156/366 (42.62%), Query Frame = 1
Query: 2056 ESLFCRACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCET--PKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCE--KPICSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKP-KPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINN--VFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            E    R C++++ +C  + C   G C +   T   C C+   + G  CD     C   PC+NG  C    N  IC C   G TG +CE  +  C ++ C + G CI K    EC C +  Y G++C     +C  + C N G C  +++N    CVC   G++ + C   +  C  N C  +G C    +   C CD G++G  C+     C  + C+NGG C  +  +  C C   F G +C+     C    CL  G C       +CNC               C    C+NGG C    +   F C C    + G+ C   +  C +  C+NG  C+   G + CNC   GY G  C+  +D
Sbjct:  455 EGFTGRHCEQDINECIPDPCH-YGTCKDGIAT-FTCLCRPG-YTGRLCDNDINECLSQPCQNGGQCTDRENGYICTCP-KGTTGVNCETNLDDCASNPC-DYGKCIDKIDGYECTC-EPGYTGKMCNINIDECASNPCRNGGTCK-DKINGF-TCVC-PDGYHDHMCLSEVNECNSNPCI-HGTCHDGINGYKCDCDAGWSGSNCDVNNNECESNPCMNGGTCKDMTGAYICTCRAGFSGPNCQTNINECASNPCLNRGTCIDDVAGYKCNCMLPYTGAICEAVLAPCSGSPCKNGGRCKESEDYETFSCECP-PGWQGQTCEIDMNECVNRPCRNGAMCQNTNGSYKCNCK-PGYAGRHCETDID 808          

HSP 3 Score: 84.3445 bits (207), Expect = 2.808e-15
Identity = 99/316 (31.33%), Postives = 139/316 (43.99%), Query Frame = 1
Query: 2200 DIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCEI--SRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCET--PKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKP-KPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCT-NKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            D+   S   NPC++G  C     +  CNC   G+ G  CEI  + C ++ CQN+  C+ + G  +C C    YEG  CET   +C  + CL+NG C+ +++N+  +C C  TGF G  C   +  C    C     CL   +S  C C EGFTG  CE+ I  C  D C + G C     +  C+C   + G+ C+     C    C  GG+C        C C +             C    C+ G     I+  + C C    YTG+ C  N   C  N C+NGG C+     F C C   GY    C  +V+
Sbjct:  311 DVDECSLGANPCEHGGRCTNTLGSFQCNCP-QGYAGPRCEIDVNECLSNPCQNDATCLDQIGEFQCICMPG-YEGLYCETNIDECASNPCLHNGKCV-DKINEF-HCEC-PTGFNGNLCQHDVDECASTPCKNGAKCLDGPNSYTCQCTEGFTGRHCEQDINECIPDPC-HYGTCKDGIATFTCLCRPGYTGRLCDNDINECLSQPCQNGGQCTDRENGYICTCPKGTTGVNCETNLDDCASNPCDYGKCIDKIDG-YECTCE-PGYTGKMCNINIDECASNPCRNGGTCKDKINGFTCVCP-DGYHDHMCLSEVN 617          

HSP 4 Score: 81.2629 bits (199), Expect = 2.375e-14
Identity = 110/387 (28.42%), Postives = 150/387 (38.76%), Query Frame = 1
Query: 2071 RACQENVKKCPKNYCQNKGRCYN-INETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGI-CQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPY-CVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKP-----ICSKDK-------CINGGKCVVVDRSPFCVCAKDFQGKSCEKP-KPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVGCPDNY--------CKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVDGVMCDYKEP 3141
            R C+ ++  C  N C N G C + IN     C+C    F G  C+     C  NPCKNG  C    N+  C C   GF+G  CE     C    C N G CI       C C    + G  C+    +C    CLN G C   Q +   Y C C   G+ G  C   +  C  + C   G C   ++   C C  G+TG  C+ P     + +K +       C N G CV    + FC C   + G  CE+    C    C  G  C    G   C C    +     E+  +C    C NGG C  + N + C+C   +       N   C   Y        C N G C    G + C C   G+ GE+C+  V+  + +  +P
Sbjct:  801 RHCETDIDDCQPNPCHNGGSCSDGIN--MFFCNC-PAGFRGPKCEEDINECASNPCKNGANCTDCVNSYTCTCQ-PGFSGIHCENNTPDCTESSCFNGGTCIDGINTFSCQCPPG-FTGNYCQHDINECDSKPCLNGGTC---QDSYGAYKCTC-PQGYTGLNCQNLVRWCDSSPCKNGGKCWQTNNFYRCECKSGWTGVYCDVPSVSCEVAAKQQGVDIAHLCRNSGMCVDTGNTHFCRCQAGYTGSYCEEQVDECSPNPCQNGATCTDYLGGYSCECVAGYHGVNCSEEINECLSHPCHNGGTCIDLINTYKCSCPRGTQGVHCEINVDDCTPFYDSVSLEPKCFNNGKCIDRVGGYNCICP-PGFVGERCEGDVNECLSNPCDP 1177          

HSP 5 Score: 80.4925 bits (197), Expect = 3.804e-14
Identity = 90/319 (28.21%), Postives = 127/319 (39.81%), Query Frame = 1
Query: 2113 CQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDC--EISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCE---------------TPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNG--NCLVRDDSAVCYCDEGFTGDKCEKPI-------------------------------------------CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKP--KPCPVGYCLYGGKCRMVNGMP--RCNCTQTNYMG 2862
            C+N G C +   T   C C+   + G +C+ +   C PNPC+NG  C        C C   G+ G +C  EI+ C +H C N G CI      +C C +   +G  CE                PKC      NNG C+ ++V     C+C   GF G RC   +  C  N C   G  NC+   +   C C +GFTG +C+  +                                           C   +C NGG C+ V +S  CVC++ + G +C+ P   PC    C  GG C+     P  +C C  TN+ G
Sbjct: 1015 CRNSGMCVDTGNTHF-CRCQ-AGYTGSYCEEQVDECSPNPCQNGATCTDYLGGYSCECVA-GYHGVNCSEEINECLSHPCHNGGTCIDLINTYKCSCPRGT-QGVHCEINVDDCTPFYDSVSLEPKC-----FNNGKCI-DRVGGY-NCIC-PPGFVGERCEGDVNECLSNPCDPRGTQNCIQLVNDYRCECRQGFTGRRCDSVVDGCKGLPCRNGGTCAVASNTERGFICKCPPGFDGATCEYDARTCGNLRCQNGGTCISVLKSSKCVCSEGYTGATCQYPVVSPCASRPCYNGGTCQFSPEEPFFQCFCP-TNFNG 1320          

HSP 6 Score: 73.559 bits (179), Expect = 4.321e-12
Identity = 111/378 (29.37%), Postives = 140/378 (37.04%), Query Frame = 1
Query: 2089 VKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKN-GICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTK--TVYEG----------QLCETPKC---PLDFCLN---NGHCLLNQ---VNQLPYCVCNSTGFYGYRCNKPI----CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRM--VNGMPRCNCTQTNYMGXX---XXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            V  C  N C N G+C    ET+  C C  + F+G  C      C  NPC+N G C     +  CNC    F+G +CE  I  C ++ C+N G C+       C C    T   G          Q    P C   P   CL      H  LN    +N++P  V          C + +       N C   G C        C C  G+TG+ C + I  C+   C +G  C     S FC C     G  C     C    C  G  C    VNG   C C    Y G                CE+GG C+     F CNC    Y G RC   V  C  N C+N   C    G+F C C + GY G  C+  +D
Sbjct:   21 VHPCASNPCANGGKCLPF-ETQYICKCP-SGFHGATCKQDINECSQNPCRNGGQCLNEFGSYRCNCQNR-FSGQNCEENIDDCPSNNCRNGGTCVDGVNTYNCQCPPDWTGKRGNMYIYIFLSYQCSVAPNCQLYPYKRCLVMSFQSHDSLNVYIIINKVPP-VVKYEDIRSQYCTEDVDECQLMPNACQNGGTCHNTYGGYNCVCVNGWTGEDCSENIDDCANAACHSGATCHDRVASFFCECPHGRTGLLCHLDNACISNPCNEGSNCDTNPVNGKAICTCP-PGYTGPACNNDVDECSLGANPCEHGGRCTNTLGSFQCNCPQ-GYAGPRCEIDVNECLSNPCQNDATCLDQIGEFQCIC-MPGYEGLYCETNID 391          

HSP 7 Score: 59.6918 bits (143), Expect = 7.596e-8
Identity = 108/389 (27.76%), Postives = 148/389 (38.05%), Query Frame = 1
Query: 2074 ACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGICQIVG-NNRICNC--TGTG---------FTGFDCEIS---------RCF-----NHKCQNNGICILK-------QGIPECDCTKTVYEGQLCETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCE-KPICSKDKCINGGKCVV--VDRSPFCVCAKDFQGKSCEKP-KPCPVGY--CLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERC-TNKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
             C++++ +C +N C+N G+C N       C+C+  +F G+ C+     C  N C+NG   + G N   C C    TG         F  + C ++         RC      +H   N  I I K       + I    CT+ V E QL        + C N G C  +       CVC   G+ G  C++ I  C    C     C  R  S  C C  G TG  C     C  + C  G  C    V+    C C   + G +C      C +G   C +GG+C    G  +CNC Q     +      +C    C+N   C      F C C    Y G  C TN   C  N C + G C     +F C C  TG+ G  C   VD
Sbjct:   54 TCKQDINECSQNPCRNGGQCLN-EFGSYRCNCQN-RFSGQNCEENIDDCPSNNCRNGGTCVDGVNTYNCQCPPDWTGKRGNMYIYIFLSYQCSVAPNCQLYPYKRCLVMSFQSHDSLNVYIIINKVPPVVKYEDIRSQYCTEDVDECQLMP------NACQNGGTC--HNTYGGYNCVC-VNGWTGEDCSENIDDCANAACHSGATCHDRVASFFCECPHGRTGLLCHLDNACISNPCNEGSNCDTNPVNGKAICTCPPGYTGPACNNDVDECSLGANPCEHGGRCTNTLGSFQCNCPQGYAGPRCEIDVNECLSNPCQNDATCLDQIGEFQCICM-PGYEGLYCETNIDECASNPCLHNGKCVDKINEFHCECP-TGFNGNLCQHDVD 429          
BLAST of notch-1 vs. Ensembl Mouse
Match: Sned1 (sushi, nidogen and EGF-like domains 1 [Source:MGI Symbol;Acc:MGI:3045960])

HSP 1 Score: 111.694 bits (278), Expect = 7.681e-24
Identity = 120/404 (29.70%), Postives = 163/404 (40.35%), Query Frame = 1
Query: 2071 RACQENVKKCPKNYCQNKGRC-YNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKN-GICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCET------PKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI-----------------------------------------CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKP--CPVGYCLYGGKCRMVNGMPRCNCTQTNYMGX--XXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCT-NKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            R C  +V +C  + CQN G C + +N    +C C    F G  C+  +  CD   C+N G CQ   ++ +C C   G+TG  CE  +  C +  CQN G C+   G   C C +  +EG  CET        C  + C N G C+    ++   C C   GF G  C + I     C   G CL   ++ +C C  GF G  CE  +                                         C  D C NGG C   + S  C C + F G+ CEK +P  C  G C  GG C+ +    RC C    + G+  +  KP  C    C NGG C      + C+C    ++G  C      C  + C NGG CE     F C C   GY G +C  +VD
Sbjct:  306 RRCHLDVNECASHPCQNGGTCTHGVN--SFSCQC-PAGFKGPTCESAQSPCDNKVCQNGGQCQAESSSAVCVCQ-AGYTGATCETDVDECSSDPCQNGGSCVDLVGNYSCICVEP-FEGPQCETGSYLVPSPCLSNPCQNGGTCV--DADEGYVCEC-PEGFMGLDCRERILNDCDCRNGGRCLGA-NTTLCQCPPGFFGLLCEFEVTATPCNMNTQCPDGGYCMEYGGSYLCVCHTDHNISHSLPSPCDSDPCFNGGSCDAHEDSYTCECPRGFHGRHCEKARPHLCSSGPCRNGGTCKEMGDEYRCTCPY-RFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCP-PGFSGRHCEIAPSPCFRSPCMNGGTCEDLGTDFSCYCQ-PGYTGHRCQAEVD 697          

HSP 2 Score: 105.145 bits (261), Expect = 7.039e-22
Identity = 105/324 (32.41%), Postives = 136/324 (41.98%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKR---PS-CDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCEISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCE-----TPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKP---ICSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCE--KPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVGC 3003
            C+ +V +C  + CQN G C ++     +C C +  F G  C+      PS C  NPC+NG  C       +C C   GF G DC      +  C+N G C L      C C    + G LCE     TP      C + G+C+    + L  CVC++     +    P C  + C   G+C   +DS  C C  GF G  CEK    +CS   C NGG C  +     C C   F G+ CE  KP  C  G C  GG C    G  +C+C            P  C    C NGG C  +   F C C    YTG RC  +V C
Sbjct:  384 CETDVDECSSDPCQNGGSCVDL-VGNYSCICVEP-FEGPQCETGSYLVPSPCLSNPCQNGGTCVDADEGYVCECP-EGFMGLDCRERILNDCDCRNGGRC-LGANTTLCQCPPGFF-GLLCEFEVTATPCNMNTQCPDGGYCMEYGGSYL--CVCHTDHNISHSLPSP-CDSDPCFNGGSCDAHEDSYTCECPRGFHGRHCEKARPHLCSSGPCRNGGTCKEMGDEYRCTCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCMNGGTCEDLGTDFSCYC-QPGYTGHRCQAEVDC 698          

HSP 3 Score: 85.1149 bits (209), Expect = 8.688e-16
Identity = 105/373 (28.15%), Postives = 140/373 (37.53%), Query Frame = 1
Query: 2098 CPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIK-RPSCDPNPCKNGICQIVGNNRICNCTGTGFTGFDCEISRC-----FNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKP---ICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCE--KP-ICSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCE-KPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXX---------------------XXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            C  N CQN G C + +E  + C+C +  F G  C  +    CD   C+NG   +  N  +C C   GF G  CE          N +C + G C+   G   C C           +P C  D C N G C  ++ +    C C   GF+G  C K    +C    C   G C    D   C C   FTG  CE  KP  C+   C NGG C        C C   F G+ CE  P PC    C+ GG C  +     C C Q  Y G +                                CE G   S ++++ +C    V     +C     C    C +GG+C+     + C CS  GY G  C+ + D
Sbjct:  433 CLSNPCQNGGTCVDADEGYV-CECPEG-FMGLDCRERILNDCD---CRNGGRCLGANTTLCQCP-PGFFGLLCEFEVTATPCNMNTQCPDGGYCMEYGGSYLCVCHTDHNISHSLPSP-CDSDPCFNGGSCDAHEDSYT--CEC-PRGFHGRHCEKARPHLCSSGPCRNGGTCKEMGDEYRCTCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCMNGGTCEDLGTDFSCYC-QPGYTGHRCQAEVDCGHPEEVEHATMRFNGTHVGSVALYTCEPGFSLSALSHIRVCQPQGVWSQPPQCIEVDECRSQPCLHGGSCQDLIADYQCLCS-PGYEGVHCELETD 793          

HSP 4 Score: 83.5741 bits (205), Expect = 2.473e-15
Identity = 99/371 (26.68%), Postives = 149/371 (40.16%), Query Frame = 1
Query: 2098 CPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPS-CDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCEISR---CFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCP--LDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI---CPQN--YCTKNGNCLVRDDSAVCYCDEGFT-------------GDKCEKPIC------SKDKCINGGKCVVVDRSPFCVCAKDFQGKSCE-KPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERC-TNKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKV 3111
            C  + C N G C + +E    C+C +  F+G  C+  RP  C   PC+NG  C+ +G+   C C    FTG  CEI +   C +  C N G C    G  +CDC    + G+ CE    P     C+N G C     +   YC     G+ G+RC   +    P+   + T   N       A+  C+ GF+             G   + P C          C++GG C  +     C+C+  ++G  CE +   C    C  GG CR +     C C +         +   C    C++GG C      ++C C    + G  C T    C  + C + G C    G   C C + GY G+ C +++
Sbjct:  545 CDSDPCFNGGSC-DAHEDSYTCECPRG-FHGRHCEKARPHLCSSGPCRNGGTCKEMGDEYRCTCP-YRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPG-FSGRHCEIAPSPCFRSPCMNGGTCEDLGTDFSCYC---QPGYTGHRCQAEVDCGHPEEVEHATMRFNGTHVGSVALYTCEPGFSLSALSHIRVCQPQGVWSQPPQCIEVDECRSQPCLHGGSCQDLIADYQCLCSPGYEGVHCELETDECQAQPCRNGGSCRDLPRAFICQCPEGFVGIHCETEVDACASSPCQHGGRCEDGGGAYLCVCPE-GFFGYNCETVSDPCFSSPCGSRGYCLASNGSHSCTCKV-GYTGKDCTKEL 906          
BLAST of notch-1 vs. Ensembl Mouse
Match: Notch1 (notch 1 [Source:MGI Symbol;Acc:MGI:97363])

HSP 1 Score: 106.301 bits (264), Expect = 4.493e-22
Identity = 105/369 (28.46%), Postives = 162/369 (43.90%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINE-TKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGI-CQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRC--NKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEK-PKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMG-----------XXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            C+  +  C  + C+N G C    +    +C C  T + G+ C++    C  +PC++G  CQ    +  C C   G+TG +CE  I  C  + C N G C        CDC    ++G  CE    +C  + C N  +C  + V+    C C   GF G  C  N P C ++ C   G C+   +S  C C  GFTG  C+  +  C    C++GG C     +  C C + + G +C+   + C    C  GG+C   N    C C ++ + G              +K        C++GG+C    +   C+C    YTG  C ++V  C  N C+NG  C  + G F C C + GY G  C ++++
Sbjct:  826 CEVVLAPCATSPCKNSGVCKESEDYESFSCVCP-TGWQGQTCEVDINECVKSPCRHGASCQNTNGSYRCLCQ-AGYTGRNCESDIDDCRPNPCHNGGSCTDGINTAFCDCLPG-FQGAFCEEDINECASNPCQNGANCT-DCVDSY-TCTC-PVGFNGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQYDVNECDSRPCLHGGTCQDSYGTYKCTCPQGYTGLNCQNLVRWCDSAPCKNGGRCWQTNTQYHCEC-RSGWTGVNCDVLSVSCEVAAQKRGIDVTLLCQHGGLCVDEGDKHYCHC-QAGYTGSYCEDEVDECSPNPCQNGATCTDYLGGFSCKC-VAGYHGSNCSEEIN 1185          

HSP 2 Score: 90.1225 bits (222), Expect = 3.790e-17
Identity = 97/308 (31.49%), Postives = 131/308 (42.53%), Query Frame = 1
Query: 2242 GICQIVGNNRICNCTGTGFTGFDCEISR-CFNHKCQNNGIC--ILKQGIPECDCTKTV-YEGQLCETP---KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKP-ICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDK--CINGGKCVVVDRSPFCVCAKDFQGKSCEKPK-PCPVGYCLYGGKCRMV-NGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG---CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            G C++      C C+G  F G  C+ S  C +  C+N G C  +   G  +  C+  + + G LC TP    C  + C N G C L  + +   C C   G+ G  C +   C  N C   G CL  + S +C C  GF G  C + +  CS++   C +GG C     S  C C     G  CE P  PC    C  GG CR   +    C C          E    CP   C+NGG C    N + C C    +TG+ CT  V       N C+NGG C    G + C C + G+ GE C + +D
Sbjct:   35 GRCEVANGTEACVCSGA-FVGQRCQDSNPCLSTPCKNAGTCHVVDHGGTVDYACSCPLGFSGPLCLTPLDNACLANPCRNGGTCDLLTLTEY-KCRC-PPGWSGKSCQQADPCASNPCANGGQCLPFESSYICRCPPGFHGPTCRQDVNECSQNPGLCRHGGTCHNEIGSYRCACRATHTGPHCELPYVPCSPSPCQNGGTCRPTGDTTHECACLPGFAGQNCEENVDDCPGNNCKNGGACVDGVNTYNCRCP-PEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVC-VNGWTGEDCSENID 337          

HSP 3 Score: 82.8037 bits (203), Expect = 5.682e-15
Identity = 102/359 (28.41%), Postives = 149/359 (41.50%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQ-LCETPKCPLDFCLNNGHCL--LNQVNQLPYCVCNSTGFYGYRC--NKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKP-KPCPVGYCLYGGKCRMVNGMPRCNCT-QTNYMGXX-XXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKV-GCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            C+ N+ +C    C++ G C + + + + C C K    G  C+I    C  NPC +G C    +   C C   G+TG  C   I  C    C N G C        C C +  ++   L E  +C  + C++ G C   LN       C C + G+ G  C  N   C  N C   G C       VC C EGF+G  C+  I  C+ + C+N G C+       C C   + G +CE    PC    C   G C+        +C   T + G+       +C +  C +G  C   N  + C C    YTG  C + +  C  N C NGG+C        C+C L G+ G  C++ ++
Sbjct:  600 CETNINECHSQPCRHGGTCQDRDNSYL-CLCLKGT-TGPNCEINLDDCASNPCDSGTCLDKIDGYECACE-PGYTGSMCNVNIDECAGSPCHNGGTCEDGIAGFTCRCPEGYHDPTCLSEVNECNSNPCIH-GACRDGLNGYK----CDC-APGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCPLPYTGATCEVVLAPCATSPCKNSGVCKESEDYESFSCVCPTGWQGQTCEVDINECVKSPCRHGASCQNTNGSYRCLC-QAGYTGRNCESDIDDCRPNPCHNGGSCTDGINTAFCDC-LPGFQGAFCEEDIN 947          

HSP 4 Score: 81.6481 bits (200), Expect = 1.141e-14
Identity = 101/360 (28.06%), Postives = 144/360 (40.00%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYN-INETKIACDCKKTQFYGEFC--DIKRPSCDPNPCKN-GICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCE-TPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI----CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCE-KPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            C+ENV  CP N C+N G C + +N     C     ++ G++C  D+      PN C+N G C        C C   G+TG DC   I  C +  C     C  +     C+C      G LC     C  + C    +C  N VN    C C S G+ G  C++ +       N C   G CL    S  C C +G+TG +CE  +  C  + C N   C+       C+C   ++G  CE     C    CL+ G C       +C C +            +C    C+NG  C    N + C C+   YTG  C   +   D    + G+C+     F C C   GY G  C+  ++
Sbjct:  254 CEENVDDCPGNNCKNGGACVDGVNTYNCRC---PPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCV-NGWTGEDCSENIDDCASAACFQGATCHDRVASFYCECPHG-RTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPS-GYTGPACSQDVDECALGANPCEHAGKCLNTLGSFECQCLQGYTGPRCEIDVNECISNPCQNDATCLDQIGEFQCICMPGYEGVYCEINTDECASSPCLHNGHCMDKINEFQCQCPKGFNGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTE-GYTGTHCEVDIDECDPDPCHYGSCKDGVATFTCLCQ-PGYTGHHCETNIN 605          

HSP 5 Score: 81.2629 bits (199), Expect = 1.797e-14
Identity = 113/361 (31.30%), Postives = 144/361 (39.89%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYN-INETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGI-CQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCT-KTVYEGQLCET--PKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEK------PKPCPVGYC---LYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERC-TNKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCD 3102
            C+ N  +C  + C + G C + INE    C C K  F G  C      C   PCKNG  C    N   C CT  G+TG  CE  I  C    C + G C  K G+    C  +  Y G  CET   +C    C + G C     + L  C+  +TG      N   C  N C  +G CL + D   C C+ G+TG  C   I  C+   C NGG C        C C + +   +C          PC  G C   L G KC    G    NC   N          +C    C NGG C  + + ++C C    ++G  C TN   C  N C N G C      + CNC L  Y G  C+
Sbjct:  487 CEINTDECASSPCLHNGHCMDKINE--FQCQCPKG-FNGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCT-EGYTGTHCEVDIDECDPDPC-HYGSC--KDGVATFTCLCQPGYTGHHCETNINECHSQPCRHGGTCQDRDNSYLCLCLKGTTG-PNCEINLDDCASNPC-DSGTCLDKIDGYECACEPGYTGSMCNVNIDECAGSPCHNGGTCEDGIAGFTCRCPEGYHDPTCLSEVNECNSNPCIHGACRDGLNGYKCDCAPGWSGTNCDINN---------NECESNPCVNGGTCKDMTSGYVCTCRE-GFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCPLP-YTGATCE 827          

HSP 6 Score: 80.1073 bits (196), Expect = 3.765e-14
Identity = 105/359 (29.25%), Postives = 141/359 (39.28%), Query Frame = 1
Query: 2095 KCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKN-GICQIVGNNRICNCTGTGFTGFDC--EISRCFNHK--CQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI----CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSC-EKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSI--INNVFICNCSNVSYTGERCTNKV---GCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
             C  N C+N G C  +  T+  C C    + G+ C    P C  NPC N G C    ++ IC C   GF G  C  +++ C  +   C++ G C  + G   C C +  + G  CE P   C    C N G C     +    C C   GF G  C + +  CP N C   G C+   ++  C C   +TG  C + +       + C NGG C        CVC   + G+ C E    C    C  G  C        C C      G  C     C    C  G  C    +N   IC C +  YTG  C+  V       N C++ G C    G F C C L GY G +C+  V+
Sbjct:  105 ACLANPCRNGGTCDLLTLTEYKCRCPPG-WSGKSCQQADP-CASNPCANGGQCLPFESSYICRCP-PGFHGPTCRQDVNECSQNPGLCRHGGTCHNEIGSYRCAC-RATHTGPHCELPYVPCSPSPCQNGGTCRPTG-DTTHECAC-LPGFAGQNCEENVDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFQGATCHDRVASFYCECPH-GRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPS-GYTGPACSQDVDECALGANPCEHAGKCLNTLGSFECQC-LQGYTGPRCEIDVN 454          

HSP 7 Score: 78.5666 bits (192), Expect = 1.050e-13
Identity = 94/308 (30.52%), Postives = 122/308 (39.61%), Query Frame = 1
Query: 2113 CQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDC--EISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCE--TPKC--PLD------FCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNG--NCLVRDDSAVCYCDEGFTGDKCEKPI-------------------------------------------CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCP-VGY--CLYGGKCRMVNGMP--RCNC 2841
            CQ+ G C +  + K  C C+   + G +C+ +   C PNPC+NG  C        C C   G+ G +C  EI+ C +  CQN G CI      +C C +   +G  CE     C  PLD       C NNG C+ +QV     C C   GF G RC   +  C  N C   G  NC+ R +   C C  G TG +CE  I                                           C   +C+NGG C+   RSP C+C   F G  C+ P   P VG   C   G C   +  P  RC C
Sbjct: 1116 CQHGGLCVDEGD-KHYCHCQAG-YTGSYCEDEVDECSPNPCQNGATCTDYLGGFSCKCV-AGYHGSNCSEEINECLSQPCQNGGTCIDLTNSYKCSCPRGT-QGVHCEINVDDCHPPLDPASRSPKCFNNGTCV-DQVGGY-TCTC-PPGFVGERCEGDVNECLSNPCDPRGTQNCVQRVNDFHCECRAGHTGRRCESVINGCRGKPCKNGGVCAVASNTARGFICRCPAGFEGATCENDARTCGSLRCLNGGTCISGPRSPTCLCLGSFTGPECQFPASSPCVGSNPCYNQGTCEPTSENPFYRCLC 1416          

HSP 8 Score: 76.6406 bits (187), Expect = 4.029e-13
Identity = 104/366 (28.42%), Postives = 149/366 (40.71%), Query Frame = 1
Query: 2077 CQENVKKCPKN--YCQNKGRCYN-INETKIACDCKKTQFYGEFCDIKRPSCDPNPCKN-GICQIVGN-NRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLC--ETPKCPL--DFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCE-KPICSKDKCINGGKCVV--VDRSPFCVCAKDFQGKSCEKP-KPCPVGY--CLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCT-NKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            C+++V +C +N   C++ G C+N I   + AC   +    G  C++    C P+PC+N G C+  G+    C C   GF G +CE  +  C  + C+N G C+       C C    + GQ C  +  +C L  + C N G C  +  +    CVC   G+ G  C++ I  C    C +   C  R  S  C C  G TG  C     C  + C  G  C    V+    C C   + G +C +    C +G   C + GKC    G   C C Q     +      +C    C+N   C      F C C    Y G  C  N   C  + C + G C     +F C C   G+ G  C   VD
Sbjct:  175 CRQDVNECSQNPGLCRHGGTCHNEIGSYRCAC---RATHTGPHCELPYVPCSPSPCQNGGTCRPTGDTTHECACL-PGFAGQNCEENVDDCPGNNCKNGGACVDGVNTYNCRCPPE-WTGQYCTEDVDECQLMPNACQNGGTC--HNTHGGYNCVC-VNGWTGEDCSENIDDCASAACFQGATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECALGANPCEHAGKCLNTLGSFECQCLQGYTGPRCEIDVNECISNPCQNDATCLDQIGEFQCICM-PGYEGVYCEINTDECASSPCLHNGHCMDKINEFQCQCP-KGFNGHLCQYDVD 530          

HSP 9 Score: 75.0998 bits (183), Expect = 1.086e-12
Identity = 106/393 (26.97%), Postives = 148/393 (37.66%), Query Frame = 1
Query: 2071 RACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGI-CQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCE--TPKCPLDFCLNNGHCLLNQVNQLPY-CVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEK-----PICSKDK-------CINGGKCVVVDRSPFCVCAKDFQGKSCEKP-KPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVGCPDNY---------------CKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVDGVMCDYKEP 3141
            R C+ ++  C  N C N G C +   T   CDC    F G FC+     C  NPC+NG  C    ++  C C   GF G  CE     C    C N G C+       C C    + G  C+    +C    CL+ G C   Q +   Y C C   G+ G  C   +  C    C   G C   +    C C  G+TG  C+       + ++ +       C +GG CV      +C C   + G  CE     C    C  G  C    G   C C    +     E+  +C  + C+NGG C  + N + C+C        R T  V C  N                C N G C    G + C C   G+ GE+C+  V+  + +  +P
Sbjct:  902 RNCESDIDDCRPNPCHNGGSCTDGINTAF-CDCLPG-FQGAFCEEDINECASNPCQNGANCTDCVDSYTCTCP-VGFNGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPG-FTGSYCQYDVNECDSRPCLHGGTC---QDSYGTYKCTC-PQGYTGLNCQNLVRWCDSAPCKNGGRCWQTNTQYHCECRSGWTGVNCDVLSVSCEVAAQKRGIDVTLLCQHGGLCVDEGDKHYCHCQAGYTGSYCEDEVDECSPNPCQNGATCTDYLGGFSCKCVAGYHGSNCSEEINECLSQPCQNGGTCIDLTNSYKCSCP-------RGTQGVHCEINVDDCHPPLDPASRSPKCFNNGTCVDQVGGYTCTCP-PGFVGERCEGDVNECLSNPCDP 1278          

HSP 10 Score: 70.0922 bits (170), Expect = 4.064e-11
Identity = 104/381 (27.30%), Postives = 142/381 (37.27%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYN-INETKIACDCKKTQFYGEFCDIKRPSCDPNPC-KNGICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCE---------TPKCPLD---FCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCE------KPKPCPVGY---CLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNV--FICNCSNVSYTGERCTNKV-GCPDNYCKNGGACEI----HRGKFGCNCSLTGYGGEQCDQKV 3111
            C+ N   C ++ C N G C + IN     C      F G +C      CD  PC   G CQ       C C   G+TG +C+  +  C +  C+N G C        C+C ++ + G  C+           K  +D    C + G C+        YC C + G+ G  C   +  C  N C     C        C C  G+ G  C + I  C    C NGG C+ +  S  C C +  QG  CE       P   P      C   G C    G   C C       +      +C    C+  G  + +  V  F C C    +TG RC + + GC    CKNGG C +     RG F C C   G+ G  C+   
Sbjct:  980 CENNTPDCTESSCFNGGTCVDGINSFTCLC---PPGFTGSYCQYDVNECDSRPCLHGGTCQDSYGTYKCTCP-QGYTGLNCQNLVRWCDSAPCKNGGRCWQTNTQYHCEC-RSGWTGVNCDVLSVSCEVAAQKRGIDVTLLCQHGGLCVDEGDKH--YCHCQA-GYTGSYCEDEVDECSPNPCQNGATCTDYLGGFSCKCVAGYHGSNCSEEINECLSQPCQNGGTCIDLTNSYKCSCPRGTQGVHCEINVDDCHPPLDPASRSPKCFNNGTCVDQVGGYTCTCPPGFVGERCEGDVNECLSNPCDPRGTQNCVQRVNDFHCEC-RAGHTGRRCESVINGCRGKPCKNGGVCAVASNTARG-FICRCP-AGFEGATCENDA 1349          

HSP 11 Score: 66.6254 bits (161), Expect = 4.203e-10
Identity = 102/365 (27.95%), Postives = 143/365 (39.18%), Query Frame = 1
Query: 2083 ENVKKCPKNYCQNKGRCYNINE---TKIACDCKKTQFYGEFCDIKRP-SCDPNPCKN-GICQIVG-NNRICNCTGTGFTGFDCEISR-CFNHKCQNNGICILKQGIPECDCTKTVYEGQLC--ETPKCPLD--FCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCL-VRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSC-EKPKPCPV--GYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVGCPDNYCKNGGACEIH--RGKFGCNCSLTGYGGEQCDQKVD 3114
            ++   C    C+N G C+ ++       AC C    F G  C      +C  NPC+N G C ++      C C   G++G  C+ +  C ++ C N G C+  +    C C    + G  C  +  +C  +   C + G C  N++     C C +T   G  C  P   C  + C   G C    D +  C C  GF G  CE+ +  C  + C NGG CV    +  C C  ++ G+ C E    C +    C  GG C   +G   C C          E    C    C  G  C      F C C +   TG  C     C  N C  G  C+ +   GK  C C  +GY G  C Q VD
Sbjct:   58 QDSNPCLSTPCKNAGTCHVVDHGGTVDYACSCP-LGFSGPLCLTPLDNACLANPCRNGGTCDLLTLTEYKCRCP-PGWSGKSCQQADPCASNPCANGGQCLPFESSYICRCPPG-FHGPTCRQDVNECSQNPGLCRHGGTC-HNEIGSY-RCACRAT-HTGPHCELPYVPCSPSPCQNGGTCRPTGDTTHECACLPGFAGQNCEENVDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFQGATCHDRVASFYCECPH-GRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCP-SGYTGPACSQDVD 414          

HSP 12 Score: 59.6918 bits (143), Expect = 5.140e-8
Identity = 60/197 (30.46%), Postives = 78/197 (39.59%), Query Frame = 1
Query: 2530 GYRCNKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKP-ICSKDKCINGGKCVVVDRSP----FCVCAKDFQGKSCEKP--KPCPVGYCLYGGKCRMVNGMP-RCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDN--YCKNGGACEIHRGKFGCNCSLTGYG 3087
            G RC++P      C   G C V + +  C C   F G +C+    C    C N G C VVD        C C   F G  C  P    C    C  GG C ++     +C C    + GK C++   C    C NGG C    + +IC C    + G  C   V  C  N   C++GG C    G + C C  T  G
Sbjct:   21 GLRCSQP---SGTCLNGGRCEVANGTEACVCSGAFVGQRCQDSNPCLSTPCKNAGTCHVVDHGGTVDYACSCPLGFSGPLCLTPLDNACLANPCRNGGTCDLLTLTEYKCRCP-PGWSGKSCQQADPCASNPCANGGQCLPFESSYICRCP-PGFHGPTCRQDVNECSQNPGLCRHGGTCHNEIGSYRCACRATHTG 212          

HSP 13 Score: 56.225 bits (134), Expect = 6.722e-7
Identity = 46/165 (27.88%), Postives = 69/165 (41.82%), Query Frame = 1
Query: 2638 GDKCEKPICSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXX-----XXXXXXXXXXYCENGGICSIIN-NVFICNCSNVSYTGERCTNKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            G +C +P      C+NGG+C V + +  CVC+  F G+ C+   PC    C   G C +V+     +   +  +G             C    C NGG C ++    + C C    ++G+ C     C  N C NGG C      + C C   G+ G  C Q V+
Sbjct:   21 GLRCSQP---SGTCLNGGRCEVANGTEACVCSGAFVGQRCQDSNPCLSTPCKNAGTCHVVDHGGTVDYACSCPLGFSGPLCLTPLDNACLANPCRNGGTCDLLTLTEYKCRCP-PGWSGKSCQQADPCASNPCANGGQCLPFESSYICRCP-PGFHGPTCRQDVN 180          
BLAST of notch-1 vs. Ensembl Mouse
Match: Notch3 (notch 3 [Source:MGI Symbol;Acc:MGI:99460])

HSP 1 Score: 104.375 bits (259), Expect = 1.676e-21
Identity = 102/358 (28.49%), Postives = 142/358 (39.66%), Query Frame = 1
Query: 2077 CQENVKKCP-KNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPC-KNGICQIVGNNRICNCTGTGFTGFDC--EISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCET--PKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCE-KPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            CQ++V +C   + C   G C N+      C C +  + G FCD     CDPNPC   G CQ    +  C+C   GF G  C  ++  C +  C   G C        C C    Y G  CE   P C    C N G C+ + V+    C+C   G+ G  C      C    C   G C        C C EGFTG +C+ P+  CS+  C NGG+CV      +C+C   + G+ C+ +  PC       G +   +                            C+ GG C        C C     TG  C ++V  C    C++GG C  + G + C C   GY G+ C+  +D
Sbjct:  808 CQQDVDECAGASPCGPHGTCTNL-PGNFRCICHRG-YTGPFCDQDIDDCDPNPCLHGGSCQDGVGSFSCSCL-DGFAGPRCARDVDECLSSPC-GPGTCTDHVASFTCACPPG-YGGFHCEIDLPDCSPSSCFNGGTCV-DGVSSFS-CLCRP-GYTGTHCQYEADPCFSRPCLHGGICNPTHPGFECTCREGFTGSQCQNPVDWCSQAPCQNGGRCV--QTGAYCICPPGWSGRLCDIQSLPCTEAAAQMGVRLEQL----------------------------CQEGGKCIDKGRSHYCVCPE-GRTGSHCEHEVDPCTAQPCQHGGTCRGYMGGYVCECP-AGYAGDSCEDNID 1125          

HSP 2 Score: 98.9821 bits (245), Expect = 6.962e-20
Identity = 104/370 (28.11%), Postives = 153/370 (41.35%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCK-NGICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCT-KTVYEGQLC--ETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI----CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRM-VNGMPRCNCTQTNYMG--XXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKV-GCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVDGVMCDYKEPG 3144
            C+ NV  C  + C + GRC +      +C C    + G  C+ +   C   PC+  G C  + +  +C C   G TG +CE  I  C ++ C   G+C  + GI   DC  +  + G LC  E  +C    C   G C+  +      C   S        N P C    C+ +G C        C C+ G++G +C + +    C    C  GG C        C CA  FQG  CE   PC    C +GG C    + +  C+C    + G   + +  +      C   G C+ +   F C C    YTG  C   +  C  N C +GG+C+   G F C+C L G+ G +C + VD  +     PG
Sbjct:  543 CERNVDDCSPDPCHH-GRCVD-GIASFSCACAPG-YTGIRCESQVDECRSQPCRYGGKCLDLVDKYLCRCP-PGTTGVNCEVNIDDCASNPC-TFGVC--RDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFHCLCPPGSLPPLCLPANHP-CAHKPCS-HGVCHDAPGGFRCVCEPGWSGPRCSQSLAPDACESQPCQAGGTCTSDGIGFRCTCAPGFQGHQCEVLSPCTPSLCEHGGHCESDPDRLTVCSCP-PGWQGPRCQQDVDECAGASPCGPHGTCTNLPGNFRCICHR-GYTGPFCDQDIDDCDPNPCLHGGSCQDGVGSFSCSC-LDGFAGPRCARDVDECLSSPCGPG 900          

HSP 3 Score: 94.3597 bits (233), Expect = 1.564e-18
Identity = 109/370 (29.46%), Postives = 158/370 (42.70%), Query Frame = 1
Query: 2074 ACQENVKKCPKNYCQNKGRCYN-INETKIACDCKKTQFYGEFCDIKRPSCDPNPC-KNGICQI--VGNNRICNCTGTGFTGFDCE--ISRCF--NHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEK------PKPCPVGYCLYGGKCRMVNGMPRCNCT-QTNYMGXXXXXXXXXXXXY-CENGGICSIINNVFICNCSNVSYTGERC-TNKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            +C +N+  C    C +   C++ +     AC   KT   G  C +   +C  NPC ++ IC    V    IC C   GFTG  C+  +  C    + C++ G C+  QG   C C +  Y G  CET   +C    C N   CL +++ Q   C+C + GF G  C   I  C  + C   G C  R +   C C  GF+G  C+  +  C+   C NG KCV       C CA+ F+G  CE+      P PC  G C        V+G+   +C     Y G +CE          C  GG C  + + ++C C   + TG  C  N   C  N C   G C     ++ C C   G+ G  C+ +++
Sbjct:  311 SCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKT---GLLCHLD-DACVSNPCHEDAICDTNPVSGRAICTCP-PGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRG-YTGPRCETDVNECLSGPCRNQATCL-DRIGQFT-CICMA-GFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSMCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCERNVDDCSPDPCHHGRC--------VDGIASFSCACAPGYTGIRCESQVDECRSQPCRYGGKCLDLVDKYLCRCPPGT-TGVNCEVNIDDCASNPC-TFGVCRDGINRYDCVCQ-PGFTGPLCNVEIN 660          

HSP 4 Score: 92.0485 bits (227), Expect = 8.132e-18
Identity = 103/361 (28.53%), Postives = 140/361 (38.78%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFC--DIKRPSCDPNPCKN-GICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCE-TPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI----CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCE-KPKPCPVGYCLYGGKCR-MVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKV-GCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            C+ NV  CP + C N G C +   T   C C   ++ G+FC  D+      PN C N G C  +     C C   G+TG  C   I  C    C +   C  +     C C      G LC     C  + C  +  C  N V+    C C   GF G  C++ +       N C   G C+    S +C C  G+TG +CE  +  C    C N   C+       C+C   F G  CE     C    C+ GG C+  VNG   C C              +C    C NG  C    + + C C+   + G  C   V  C  + C + G C      F C C+  GY G +C+ +VD
Sbjct:  234 CEVNVDDCPGHRCLNGGTCVDGVNT-YNCQCPP-EWTGQFCTEDVDECQLQPNACHNGGTCFNLLGGHSCVCV-NGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMG-KTGLLCHLDDACVSNPCHEDAICDTNPVSGRAICTC-PPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGF-SCTCPSGFSGSMCQLDVDECASTPCRNGAKCVDQPDGYECRCAE-GFEGTLCERNVDDCSPDPCHH-GRCVDGIASFSCACA-PGYTGIRCESQVD 585          

HSP 5 Score: 90.1225 bits (222), Expect = 3.285e-17
Identity = 100/362 (27.62%), Postives = 141/362 (38.95%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGICQIVG-NNRICNC----TGTGFTGFDCEISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCET--PKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCN-KPICPQNYCTKNGNCLVRDDS--AVCYCDEGFTGDKCEKPI--CS--KDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKP-KPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            C+  V  C  + C+N G C   ++    C C    F G+ C++    C  + C NG   + G N   C C    TG  F   D +  +   + C N G C    G   C C    + G+ C      C    C +   C  ++V    YC C   G  G  C+    C  N C ++  C     S  A+C C  GFTG  C++ +  CS   + C + G+CV    S  C C + + G  CE     C  G C     C    G   C C              +C    C NGG+C    N F C C +  ++G  C   V  C    C+NG  C      + C C+  G+ G  C++ VD
Sbjct:  195 CENPVVPCAPSPCRNGGTCRQSSDVTYDCACLPG-FEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQ-FCTEDVDECQLQPNACHNGGTCFNLLGGHSCVCVNG-WTGESCSQNIDDCATAVCFHGATC-HDRVASF-YCAC-PMGKTGLLCHLDDACVSNPCHEDAICDTNPVSGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPS-GFSGSMCQLDVDECASTPCRNGAKCVDQPDGYECRCA-EGFEGTLCERNVD 548          

HSP 6 Score: 86.2705 bits (212), Expect = 4.379e-16
Identity = 101/379 (26.65%), Postives = 142/379 (37.47%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPC-KNGICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCPL------------DFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCE-KPKPCPVG-------YCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNV---FICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGK-----FGCNCSLTGYGGEQCDQ 3105
            C+ ++  C  + C N G C +   +  +C C+   + G  C  +   C   PC   GIC        C C   GFTG  C+  +  C    CQN G C+  Q    C C    + G+LC+    P               C   G C+     +  YCVC   G  G  C   +  C    C   G C       VC C  G+ GD CE  I  C+   C NGG C+ +     C C     G  CE     C +G        CL+ G C  + G  RCNC              +C    C        + +    F C C +  +TG RC   +  C    C++GG C    G+     F C+C +  + G +C++
Sbjct:  922 CEIDLPDCSPSSCFNGGTCVD-GVSSFSCLCRPG-YTGTHCQYEADPCFSRPCLHGGICNPTHPGFECTCR-EGFTGSQCQNPVDWCSQAPCQNGGRCV--QTGAYCICPPG-WSGRLCDIQSLPCTEAAAQMGVRLEQLCQEGGKCI--DKGRSHYCVC-PEGRTGSHCEHEVDPCTAQPCQHGGTCRGYMGGYVCECPAGYAGDSCEDNIDECASQPCQNGGSCIDLVARYLCSCPPGTLGVLCEINEDDCDLGPSLDSGVQCLHNGTCVDLVGGFRCNCPPGYTGLHCEADINECRPGACHAAHTRDCLQDPGGHFRCVC-HPGFTGPRCQIALSPCESQPCQHGGQCRHSLGRGGGLTFTCHC-VPPFWGLRCER 1289          

HSP 7 Score: 85.1149 bits (209), Expect = 1.059e-15
Identity = 103/354 (29.10%), Postives = 139/354 (39.27%), Query Frame = 1
Query: 2113 CQNKGRCYNINET-KIACDCKKTQFYGEFCDIKRPSCDPNPCKN-GICQ---IVGNNRI-CNCTGTGFTGFDC-EISRCFNHKCQNNGIC-ILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAV-CYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSC-EKPKPCPV--GYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVGCPDNYCKNGGACEIH--RGKFGCNCSLTGYGGEQCDQKVD 3114
            C N GRC +   + + AC C    + GE C ++ P C   PC   G+CQ   + G  R  C C   GF G DC +   C +  C +   C +   G   C C    Y+GQ C++   +C       +G   LN       C C   G+ G  C  P+  C  + C   G C    D    C C  GF G  CE  +  C   +C+NGG CV    +  C C  ++ G+ C E    C +    C  GG C  + G   C C          +    C    C +G  C      F C C  +  TG  C     C  N C     C+ +   G+  C C   G+ G  CDQ VD
Sbjct:   49 CANGGRCTHQQPSLEAACLCLPG-WVGERCQLEDP-CHSGPCAGRGVCQSSVVAGTARFSCRCL-RGFQGPDCSQPDPCVSRPCVHGAPCSVGPDGRFACACPPG-YQGQSCQSDIDECRSGTTCRHGGTCLNTPGSF-RCQC-PLGYTGLLCENPVVPCAPSPCRNGGTCRQSSDVTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNLLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACP-MGKTGLLCHLDDACVSNPCHEDAICDTNPVSGRAICTCP-PGFTGGACDQDVD 394          

HSP 8 Score: 68.9366 bits (167), Expect = 8.702e-11
Identity = 83/289 (28.72%), Postives = 112/289 (38.75%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCEI---------SRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFC--LNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNC---LVRDD--SAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGY---------CLYGGKCRMVNGMP--RCNC 2841
            C+  V  C    CQ+ G C       + C+C    + G+ C+     C   PC+NG  C  +    +C+C   G  G  CEI         S     +C +NG C+   G   C+C    Y G  CE    +C    C   +   CL +       CVC+  GF G RC   +  C    C   G C   L R    +  C+C   F G +CE+    C + +C  G  C    R P C C     G SC   +  P G          CL+GG C  V  +P  RC C
Sbjct: 1082 CEHEVDPCTAQPCQHGGTCRGYMGGYV-CECP-AGYAGDSCEDNIDECASQPCQNGGSCIDLVARYLCSCP-PGTLGVLCEINEDDCDLGPSLDSGVQCLHNGTCVDLVGGFRCNCPPG-YTGLHCEADINECRPGACHAAHTRDCLQDPGGHF-RCVCHP-GFTGPRCQIALSPCESQPCQHGGQCRHSLGRGGGLTFTCHCVPPFWGLRCERVARSCRELQCPVGIPCQQTARGPRCACPPGLSGPSCRVSRASPSGATNASCASAPCLHGGSCLPVQSVPFFRCVC 1364          

HSP 9 Score: 68.9366 bits (167), Expect = 8.999e-11
Identity = 74/267 (27.72%), Postives = 103/267 (38.58%), Query Frame = 1
Query: 2074 ACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPC--------KNGIC-QIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQ--NNGICILKQGIP-ECDCTKTVYEGQLCETPKCPLDF--CLNNGHCL--LNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCE----------KPICSKDKCINGGKCVVVDRSPF--CVCAKDFQGKSCEKPKPCP 2778
            +C++N+ +C    CQN G C ++   +  C C      G  C+I    CD  P          NG C  +VG  R CNC   G+TG  CE  I+ C    C   +   C+   G    C C    + G  C+    P +   C + G C   L +   L +       F+G RC +    C +  C     C        C C  G +G  C              C+   C++GG C+ V   PF  CVCA  + G  CE P   P
Sbjct: 1119 SCEDNIDECASQPCQNGGSCIDL-VARYLCSCPPGTL-GVLCEINEDDCDLGPSLDSGVQCLHNGTCVDLVGGFR-CNCP-PGYTGLHCEADINECRPGACHAAHTRDCLQDPGGHFRCVCHPG-FTGPRCQIALSPCESQPCQHGGQCRHSLGRGGGLTFTCHCVPPFWGLRCERVARSCRELQCPVGIPCQQTARGPRCACPPGLSGPSCRVSRASPSGATNASCASAPCLHGGSCLPVQSVPFFRCVCAPGWGGPRCETPSAAP 1380          
BLAST of notch-1 vs. Ensembl Mouse
Match: Notch2 (notch 2 [Source:MGI Symbol;Acc:MGI:97364])

HSP 1 Score: 102.449 bits (254), Expect = 5.433e-21
Identity = 110/372 (29.57%), Postives = 151/372 (40.59%), Query Frame = 1
Query: 2050 PKESLFCRACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG---ICQIVGNNRICNCTGTGFTGFDCEISR---CF-NHKCQNNGIC-ILKQGIPECDCTKTVYEGQLCETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICP---QNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPF-CVCAKDFQGKSCEKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG---CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            P  +L CR  QE         C N+G C   +     C C +  F GE+C  + P C+ N C+NG   + Q +     C C   GFTG DC+ S    CF +  CQN G C +L +   EC C +  + G+ C+     L     NG    +  +Q   C C   G  G +C   I        C   G CL    S  C C +GFTG  C+ P   C+   C+NGG C       F C C   F+G +CE                R ++  P                        C+NGG+C    N + C C    +TG+ CT  V       N C+NGG C    G +GC C + G+ G+ C + +D
Sbjct:   22 PAHALQCRGGQEP--------CVNEGTCVTYHNGTGFCRCPEG-FLGEYCQHRDP-CEKNRCQNGGTCVPQGMLGKATCRCA-PGFTGEDCQYSTSHPCFVSRPCQNGGTCHMLSRDTYECTC-QVGFTGKQCQWTDACLSHPCENGSTCTSVASQF-SCKC-PAGLTGQKCEADINECDIPGRCQHGGTCLNLPGSYRCQCPQGFTGQHCDSPYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCE----------------RNIDDCPN---------------------HKCQNGGVCVDGVNTYNCRCP-PQWTGQFCTEDVDECLLQPNACQNGGTCTNRNGGYGCVC-VNGWSGDDCSENID 340          

HSP 2 Score: 88.5817 bits (218), Expect = 1.070e-16
Identity = 107/356 (30.06%), Postives = 150/356 (42.13%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKN-GICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCT-KTVYEGQLC--ETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKP-KPCPVGYCLYGGKCRMVNGMPRCNCT-QTNYMGXX-XXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCD 3102
            C+ +  +C  N CQN G C N+      C CKK  F G  C +    C  NPC N G C    +   C+C    +TG +C+  ++ C  + C+N  +C          C     ++G+ C  +  +C    C+NNG C   Q + +  C     GF G  C + I  C  N C   G+C+   ++  C C  GF GDKC+  +  C  + C NGG C     S  C C   F G  CE     C    C  GG C  V+G+   +C     + G        +C    C N G C      + C C  + YTG+ C   V  C  + CKN G C   + +  C C   G+ G  CD
Sbjct:  754 CEVDKNECLSNPCQNGGTCNNL-VNGYRCTCKKG-FKGYNCQVNIDECASNPCLNQGTCFDDVSGYTCHCM-LPYTGKNCQTVLAPCSPNPCENAAVCKEAPNFESFSCLCAPGWQGKRCTVDVDECISKPCMNNGVCHNTQGSYVCEC---PPGFSGMDCEEDINDCLANPCQNGGSCVDHVNTFSCQCHPGFIGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCTCPAGFHGVHCENNIDECTESSCFNGGTC--VDGINSFSCLCPVGFTGPFCLHDINECSSNPCLNAGTCVDGLGTYRCICP-LGYTGKNCQTLVNLCSRSPCKNKGTCVQEKARPHCLCP-PGWDGAYCD 1099          

HSP 3 Score: 87.8113 bits (216), Expect = 1.685e-16
Identity = 108/382 (28.27%), Postives = 153/382 (40.05%), Query Frame = 1
Query: 2026 QKPNVNSFPKESLFC------RACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKN-GICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCET--PKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGYCLYGGKCR---MVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            + PN  SF   S  C      + C  +V +C    C N G C+N   + + C+C    F G  C+     C  NPC+N G C    N   C C   GF G  C+  ++ C +  C+N G C        C C    + G  CE    +C    C N G C ++ +N    C+C   GF G  C   I  C  N C   G C+    +  C C  G+TG  C+  +  CS+  C N G CV     P C+C   + G  C+          +    C+   +  G+P                     E  C++ GIC    N   C C  + YTG  C  ++  C  N C++G  C    G + C C + GY G  C+ +VD
Sbjct:  850 EAPNFESF---SCLCAPGWQGKRCTVDVDECISKPCMNNGVCHNTQGSYV-CECPPG-FSGMDCEEDINDCLANPCQNGGSCVDHVNTFSCQCH-PGFIGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCTCPAG-FHGVHCENNIDECTESSCFNGGTC-VDGINSF-SCLC-PVGFTGPFCLHDINECSSNPCLNAGTCVDGLGTYRCICPLGYTGKNCQTLVNLCSRSPCKNKGTCVQEKARPHCLCPPGWDGAYCD----------VLNVSCKAAALQKGVP--------------------VEHLCQHSGICINAGNTHHCQCP-LGYTGSYCEEQLDECASNPCQHGATCNDFIGGYRCEC-VPGYQGVNCEYEVD 1189          

HSP 4 Score: 80.1073 bits (196), Expect = 3.628e-14
Identity = 108/369 (29.27%), Postives = 156/369 (42.28%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQI--VGNNRICNCTGTGFTGFDC-----EISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEK------PKPCPVGYCLYGGKCRMVNGMPRCNCT-QTNYMGXX-XXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCT-NKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            C EN+  C    C     C +      +C C + +  G  C +   +C  NPC  G +C    +    IC C   G+ G DC     E +   ++ C++ G C+   G   C+C K  Y G  CE    +C  D C N+  CL +++     C+C   GF G  C   +  C  N C  NG C+ + +   C C  GFTG  C+  I  CS   C+NG KC+       C CA  F G  C++      P PC  G C         +G+    C     YMG    ++  +C    C N G C  + N + CNC     +G  C  N   C  N C + G C     ++ C CS  G+ G++C+  +D
Sbjct:  335 CSENIDDCAYASCTPGSTCID-RVASFSCLCPEGK-AGLLCHLDD-ACISNPCHKGALCDTNPLNGQYICTCP-QGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKG-YAGPRCEMDINECHSDPCQNDATCL-DKIGGF-TCLC-MPGFKGVHCELEVNECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGILCDENIDNCDPDPCHHGQCQ--------DGIDSYTCICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNC-QPGTSGLNCEINFDDCASNPCMH-GVCVDGINRYSCVCS-PGFTGQRCNIDID 684          

HSP 5 Score: 79.7221 bits (195), Expect = 5.251e-14
Identity = 107/372 (28.76%), Postives = 154/372 (41.40%), Query Frame = 1
Query: 2071 RACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCK-----------NGICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCE--TPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI---CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGK--CVVVDRSPFCVCAKDFQGKSCEK-PKPCPVGYCLYGGKCRMVNGMPR---CNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVGCPDNYCKNGGACEIHRG--KFGCNCSLTGYGGEQCD 3102
            + CQ  V  C ++ C+NKG C    + +  C C    + G +CD+   SC     +           +GIC   GN   C C   G+TG  CE  +  C ++ CQ+   C    G   C+C    Y+G  CE    +C    C N G C+ + VN    C C   G  G  C + I       +C   G C+ R     C C  GF G++CE  I  C  + C + G   CV +  +  C+C   F G+ CE     CP   CL GG C + + MP    C C    + G +C+      +  C  G  C   ++   C C N          + GC  N C++GG C   R    + C C  + +GG  C+
Sbjct: 1058 KNCQTLVNLCSRSPCKNKGTCVQ-EKARPHCLCPPG-WDGAYCDVLNVSCKAAALQKGVPVEHLCQHSGICINAGNTHHCQCP-LGYTGSYCEEQLDECASNPCQHGATCNDFIGGYRCECVPG-YQGVNCEYEVDECQNQPCQNGGTCI-DLVNHF-KCSC-PPGTRGLLCEENIDECAGGPHCLNGGQCVDRIGGYTCRCLPGFAGERCEGDINECLSNPCSSEGSLDCVQLKNNYNCICRSAFTGRHCETFLDVCPQKPCLNGGTCAVASNMPDGFICRCP-PGFSGARCQSSCGQVK--CRRGEQCIHTDSGPRCFCLNPKDC------ESGCASNPCQHGGTCYPQRQPPHYSCRCPPS-FGGSHCE 1412          

HSP 6 Score: 75.485 bits (184), Expect = 9.705e-13
Identity = 119/431 (27.61%), Postives = 154/431 (35.73%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG---ICQIVGNNRIC------------------------NCTG----------TGFTGFDCEISR--CFNHKCQNNGICILKQGIPECDCTKTVYEGQLCET--PKCPLDFCLNNGHCLLNQVN-----QLPY---------------------------------CVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKP-KPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            C+ N   C  N C +      IN     C      F G+ C+I    C  NPC+ G   I  + G   IC                        NCTG           G+ G +CE+ +  C ++ CQN G C        C C K  ++G  C+    +C  + CLN G C  +         LPY                                 C+C + G+ G RC   +  C    C  NG C     S VC C  GF+G  CE+ I  C  + C NGG CV    +  C C   F G  C+     C    C  GG C        C C    +         +C E  C NGG C    N F C C  V +TG  C + +  C  N C N G C    G + C C L GY G+ C   V+
Sbjct:  642 CEINFDDCASNPCMHGVCVDGINRYSCVC---SPGFTGQRCNIDIDECASNPCRKGATCINDVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGVNCEVDKNECLSNPCQNGGTCNNLVNGYRCTCKKG-FKGYNCQVNIDECASNPCLNQGTCFDDVSGYTCHCMLPYTGKNCQTVLAPCSPNPCENAAVCKEAPNFESFSCLC-APGWQGKRCTVDVDECISKPCMNNGVCHNTQGSYVCECPPGFSGMDCEEDINDCLANPCQNGGSCVDHVNTFSCQCHPGFIGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCTCPAGFHGVHCENNIDECTESSCFNGGTCVDGINSFSCLCP-VGFTGPFCLHDINECSSNPCLNAGTCVDGLGTYRCICPL-GYTGKNCQTLVN 1065          

HSP 7 Score: 59.6918 bits (143), Expect = 6.116e-8
Identity = 85/299 (28.43%), Postives = 112/299 (37.46%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYN-INETKIACDCKKTQFYGEFCDIKRPSCDPNP-CKNG-ICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGI--CILKQGIPECDCTKTVYEGQLCET--PKCPLDFCLNNGHCLLNQVNQLP---YCVCNSTGFYGYRCNKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPICSKDKCINGGKCVVVDRSPF--CVCAKDFQGKSCE--------KPKPCPVGYC-------------------LYGGKCRMVNGMPRCNCTQT 2850
            C+  V +C    CQN G C + +N  K +C        G  C+     C   P C NG  C        C C   GF G  CE  I+ C ++ C + G   C+  +    C C ++ + G+ CET    CP   CLN G C +   + +P    C C   GF G RC    C Q  C +   C+  D    C+C        CE   C+ + C +GG C    + P   C C   F G  CE         P  C   YC                     GG C +    P  NCT T
Sbjct: 1184 CEYEVDECQNQPCQNGGTCIDLVNHFKCSC---PPGTRGLLCEENIDECAGGPHCLNGGQCVDRIGGYTCRCL-PGFAGERCEGDINECLSNPCSSEGSLDCVQLKNNYNCIC-RSAFTGRHCETFLDVCPQKPCLNGGTCAV--ASNMPDGFICRC-PPGFSGARCQS-SCGQVKCRRGEQCIHTDSGPRCFC---LNPKDCES-GCASNPCQHGGTCYPQRQPPHYSCRCPPSFGGSHCELYTAPTSTPPATCQSQYCADKARDGICDEACNSHACQWDGGDCSLTMEDPWANCTST 1469          
BLAST of notch-1 vs. Ensembl Mouse
Match: Tnxb (tenascin XB [Source:MGI Symbol;Acc:MGI:1932137])

HSP 1 Score: 99.3673 bits (246), Expect = 5.328e-20
Identity = 113/400 (28.25%), Postives = 164/400 (41.00%), Query Frame = 1
Query: 2086 NVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGICQIVGNNRICNCTGTGFTGFDCEISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPICSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQK------------VDGV-MCDYKEPGYAITAFKPPMVSSGIVTSMGFQTFVKTGTLFCYE 3246
            + + CP++ C+ +GRC    + +  CD     + G+ C ++  SC  +  + G C+   + R C C   G+TG DC    C    C+  G C  + G+  C      Y G+ C    CP D C   G+C      +   CVC   G+ G  C    CP + C   G C+       C C+ GFTG+ C    C  D C   G C     +  CVCA  + G  C   + CP   C   G+C  +NG+  C C +  Y G+ C   +   +  C   G+C       +C C +  Y GE C+ +  CP + C+  G CE  R    C C+  GY G  C  +            V GV MC     G      +PP  +S      G +   + G   C E
Sbjct:  356 STRTCPRD-CRGRGRC---EDGECICD---AGYSGDDCGVR--SCPGDCNQRGHCE---DGR-CVCW-PGYTGADCSTRAC-PRDCRGRGRC--EDGVCVCHAG---YSGEDCGVRSCPGD-CRGRGNC------ESGRCVC-WPGYTGRDCGTRACPGD-CRGRGRCV----DGRCVCNPGFTGEDCGSRRCPGD-CRGHGHC----ENGVCVCAVGYSGDDCST-RSCPSD-CRGRGQC--LNGL--CECDE-GYSGEDCGIRRCPRD--CSQHGVC----QDGLCMC-HAGYAGEDCSIRT-CPAD-CRRRGRCEDGR----CVCN-PGYTGPACATRTCPADCRGRGRCVQGVCMCYVGYSGEDCGQEEPP--ASACPGGCGPRELCRAGQCVCVE 694          

HSP 2 Score: 97.8265 bits (242), Expect = 1.574e-19
Identity = 107/381 (28.08%), Postives = 151/381 (39.63%), Query Frame = 1
Query: 2068 CRA------CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIK---RPSCDPNPCKNGICQIVGNNRICNCTGTGFTGFDCEISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPICSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPV----------GYCL----YGGKCRMVNGMP-----RCNCTQ------TNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQK 3108
            CRA      C +  + CP+N C  +GRC    E +  CD     + GE C ++   R       C+NG+C       +CN    G++G DC +  C    C   G C  + G   CD     Y G+ C    CP D C + G C+  +      CVC   G+ G  C+   CP++ C   G C    +   C CD G++GD C    C  D C   G C        CVC   + G  C   + CP           G C+    Y G+   V   P     R NC          Y G+ C       +  C   G C  ++   +C   N  +TGE C ++  CP + C+  G CE       C C++ GY G+ C  +
Sbjct:  222 CRAGFSGPDCSQ--RSCPRN-CNQRGRC---EEGRCVCD---PGYSGEDCGVRSCPRGCSQRGRCENGLC-------VCN---PGYSGEDCGVRNC-PRGCSQRGRC--EDGRCVCD---PGYSGEDCSMRTCPWD-CGDGGRCVDGR------CVC-WPGYSGEDCSTRTCPRD-CRGRGRC----EDGECICDAGYSGDDCGVRSCPGD-CNQRGHC----EDGRCVCWPGYTGADCST-RACPRDCRGRGRCEDGVCVCHAGYSGEDCGVRSCPGDCRGRGNCESGRCVCWPGYTGRDCGTRACPGD--CRGRGRC--VDGRCVC---NPGFTGEDCGSR-RCPGD-CRGHGHCE----NGVCVCAV-GYSGDDCSTR 544          

HSP 3 Score: 90.5077 bits (223), Expect = 3.091e-17
Identity = 80/258 (31.01%), Postives = 112/258 (43.41%), Query Frame = 1
Query: 2092 KKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKN-GICQIVGNNRICNCTGTGFTGFDCEISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPICSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMG 2862
            ++CP + C+  G C N       C C    + G+ C  +  SC P+ C+  G C     N +C C   G++G DC I RC    C  +G+C  + G+  C      Y G+ C    CP D C   G C      +   CVCN  G+ G  C    CP + C   G C+      VC C  G++G+ C +       C  G     + R+  CVC + F+G  C   + CP G C   G+C  + G  RC C Q  Y G
Sbjct:  513 RRCPGD-CRGHGHCENG-----VCVCA-VGYSGDDCSTR--SC-PSDCRGRGQCL----NGLCECD-EGYSGEDCGIRRC-PRDCSQHGVC--QDGLCMCHAG---YAGEDCSIRTCPAD-CRRRGRC------EDGRCVCNP-GYTGPACATRTCPAD-CRGRGRCV----QGVCMCYVGYSGEDCGQEEPPASACPGGCGPRELCRAGQCVCVEGFRGPDC-AIQTCP-GDCRSRGEC--IQG--RCVC-QEGYAG 729          

HSP 4 Score: 86.6557 bits (213), Expect = 4.033e-16
Identity = 77/253 (30.43%), Postives = 112/253 (44.27%), Query Frame = 1
Query: 2341 CQNNGICILKQGIPECDCTKTVYEGQLCETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPICSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQC 3099
            C + G C+  +    C C    Y G  C  P CP D C   G C+         CVC + GF G  C++  CP+N C + G C    +   C CD G++G+ C    C +  C   G+C     +  CVC   + G+ C   + CP G C   G+C   +G  RC C    Y G+ C       +  C +GG C  ++   +C      Y+GE C+ +  CP + C+  G CE   G+  C+    GY G+ C
Sbjct:  178 CNDQGRCVRGR----CVCFPG-YSGPSCSWPSCPGD-CQGRGRCVKG------VCVCRA-GFSGPDCSQRSCPRN-CNQRGRC----EEGRCVCDPGYSGEDCGVRSCPRG-CSQRGRC----ENGLCVCNPGYSGEDC-GVRNCPRG-CSQRGRCE--DG--RCVC-DPGYSGEDCSMRTCPWD--CGDGGRC--VDGRCVC---WPGYSGEDCSTRT-CPRD-CRGRGRCE--DGECICD---AGYSGDDC 386          

HSP 5 Score: 70.0922 bits (170), Expect = 4.584e-11
Identity = 61/222 (27.48%), Postives = 88/222 (39.64%), Query Frame = 1
Query: 2086 NVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGICQIVGNNRICNCTGTGFTGFDCEISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCPLDFCLNNGHCLLN------------------------------QVNQLPYCVCNSTGFYGYRCNKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI 2661
            + + CP + C+ +G+C N       C+C +  + GE C I+R  C  +  ++G+CQ    + +C C   G+ G DC I  C    C+  G C  + G   C C    Y G  C T  CP D C   G C+                                ++ +   CVC   GF G  C    CP + C   G C+       C C EG+ GD C + I
Sbjct:  542 STRSCPSD-CRGRGQCLNG-----LCECDEG-YSGEDCGIRR--CPRDCSQHGVCQ----DGLCMCHA-GYAGEDCSIRTC-PADCRRRGRC--EDG--RCVCNPG-YTGPACATRTCPAD-CRGRGRCVQGVCMCYVGYSGEDCGQEEPPASACPGGCGPRELCRAGQCVC-VEGFRGPDCAIQTCPGD-CRSRGECI----QGRCVCQEGYAGDDCGEEI 736          

HSP 6 Score: 68.9366 bits (167), Expect = 8.389e-11
Identity = 67/230 (29.13%), Postives = 85/230 (36.96%), Query Frame = 1
Query: 2470 CLLNQVNQLPYCVCN-STGFYGYRCNKPI-------------CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPICSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRMVNGMPRCNCT---QTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQK 3108
            C L+ V  L  C C+   G+ G  C+ P              CP++ C   G C+       C C  G++G  C  P C  D C   G+CV       CVC   F G  C + + CP   C   G+C       RC C         G +           CENG          +C C N  Y+GE C  +  CP   C   G CE  R    C C   GY GE C  +
Sbjct:  132 CSLHGVFDLSRCACSCEPGWGGPTCSDPTDTKTPTSSPPSKSCPED-CNDQGRCV----RGRCVCFPGYSGPSCSWPSCPGD-CQGRGRCV----KGVCVCRAGFSGPDCSQ-RSCPRN-CNQRGRCE----EGRCVCDPGYSGEDCGVRSCPRGCSQRGRCENG----------LCVC-NPGYSGEDCGVR-NCPRG-CSQRGRCEDGR----CVCD-PGYSGEDCSMR 327          
BLAST of notch-1 vs. UniProt/SwissProt
Match: sp|Q9R172|NOTC3_RAT (Neurogenic locus notch homolog protein 3 OS=Rattus norvegicus OX=10116 GN=Notch3 PE=2 SV=2)

HSP 1 Score: 116.316 bits (290), Expect = 2.623e-24
Identity = 106/353 (30.03%), Postives = 152/353 (43.06%), Query Frame = 1
Query: 2077 CQENVKKCP-KNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDC--EISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPK-PCPVG----------YCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNC 3069
            CQ++V +C   + C   G C N+  +   C C    + G FCD     CDPNPC NG  CQ    +  C+C  +GF G  C  ++  C +  C   G C        C C    Y G  CET    C    C N G C+ + VN    C+C   G+ G  C   +  C    C   G C        C C EGFTG++C+ P+  CS+  C NGG+C  V    +C+C  ++ G  C+ P  PC              C  GG+C   +    C C +        ++   C  + C++GG C      ++C C    Y+G+ C + V  C    C+NGG+C      + C+C
Sbjct:  809 CQQDVDECAGASPCGPHGTCTNLPGS-FRCICHGG-YTGPFCDQDIDDCDPNPCLNGGSCQDGVGSFSCSCL-SGFAGPRCARDVDECLSSPC-GPGTCTDHVASFTCTCPPG-YGGFHCETDLLDCSPSSCFNGGTCV-DGVNSFS-CLCRP-GYTGTHCQYKVDPCFSRPCLHGGICNPTHSGFECTCREGFTGNQCQNPVDWCSQAPCQNGGRC--VQTGAYCICPPEWSGPLCDIPSLPCTEAAAHMGVRLEQLCQAGGQCIDKDHSHYCVCPEGRMGSHCEQEVDPCTAQPCQHGGTCRGYMGGYVCECPT-GYSGDSCEDDVDECASQPCQNGGSCIDLVAHYLCSC 1150          

HSP 2 Score: 104.76 bits (260), Expect = 9.502e-21
Identity = 106/370 (28.65%), Postives = 154/370 (41.62%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCK-NGICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCT-KTVYEGQLC--ETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI----CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRM-VNGMPRCNCTQTNYMG--XXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKV-GCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVDGVMCDYKEPG 3144
            C+ NV  C  + C + GRC +      +C C    + G  C+ +   C   PC+  G C  + +  +C C   G TG +CE  I  C ++ C   G+C  + GI   DC  +  + G LC  E  +C    C   G C+  +      C   S        N P C    C+ +G C        C CD G++G +C + +    C    C  GG C        C CA  FQG  CE   PC    C +GG C    + +  C+C    + G   + +  +      C   G C+ +   F C C    YTG  C   +  C  N C NGG+C+   G F C+C L+G+ G +C + VD  +     PG
Sbjct:  544 CERNVDDCSPDPCHH-GRCVD-GIASFSCACAPG-YTGIRCESQVDECRSQPCRYGGKCLDLVDKYLCRCP-PGTTGVNCEVNIDDCASNPC-TFGVC--RDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFHCLCPPGSLPPLCLPANHP-CAHKPCS-HGVCHDAPGGFQCVCDPGWSGPRCSQSLAPDACESQPCQAGGTCTSDGIGFHCTCAPGFQGHQCEVLSPCTPSLCEHGGHCESDPDQLTVCSCP-PGWQGPRCQQDVDECAGASPCGPHGTCTNLPGSFRCICHG-GYTGPFCDQDIDDCDPNPCLNGGSCQDGVGSFSCSC-LSGFAGPRCARDVDECLSSPCGPG 901          

HSP 3 Score: 94.3597 bits (233), Expect = 1.241e-17
Identity = 109/370 (29.46%), Postives = 158/370 (42.70%), Query Frame = 1
Query: 2074 ACQENVKKCPKNYCQNKGRCYN-INETKIACDCKKTQFYGEFCDIKRPSCDPNPC-KNGICQI--VGNNRICNCTGTGFTGFDCE--ISRCF--NHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEK------PKPCPVGYCLYGGKCRMVNGMPRCNCT-QTNYMGXXXXXXXXXXXXY-CENGGICSIINNVFICNCSNVSYTGERC-TNKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            +C +N+  C    C +   C++ +     AC   KT   G  C +   +C  NPC ++ IC    V    IC C   GFTG  C+  +  C    + C++ G C+  QG   C C +  Y G  CET   +C    C N   CL +++ Q   C+C + GF G  C   I  C  + C   G C  R +   C C  GF+G  C+  +  C+   C NG KCV       C CA+ F+G  CE+      P PC  G C        V+G+   +C     Y G +CE          C  GG C  + + ++C C   + TG  C  N   C  N C   G C     ++ C C   G+ G  C+ +++
Sbjct:  312 SCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKT---GLLCHLD-DACVSNPCHEDAICDTNPVSGRAICTCP-PGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRG-YTGPRCETDVNECLSGPCRNQATCL-DRIGQFT-CICMA-GFTGTFCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCERNVDDCSPDPCHHGRC--------VDGIASFSCACAPGYTGIRCESQVDECRSQPCRYGGKCLDLVDKYLCRCPPGT-TGVNCEVNIDDCASNPC-TFGVCRDGINRYDCVCQ-PGFTGPLCNVEIN 661          

HSP 4 Score: 92.0485 bits (227), Expect = 5.737e-17
Identity = 103/361 (28.53%), Postives = 140/361 (38.78%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFC--DIKRPSCDPNPCKN-GICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCE-TPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI----CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCE-KPKPCPVGYCLYGGKCR-MVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKV-GCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            C+ NV  CP + C N G C +   T   C C   ++ G+FC  D+      PN C N G C  +     C C   G+TG  C   I  C    C +   C  +     C C      G LC     C  + C  +  C  N V+    C C   GF G  C++ +       N C   G C+    S +C C  G+TG +CE  +  C    C N   C+       C+C   F G  CE     C    C+ GG C+  VNG   C C              +C    C NG  C    + + C C+   + G  C   V  C  + C + G C      F C C+  GY G +C+ +VD
Sbjct:  235 CEVNVDDCPGHRCLNGGTCVDGVNT-YNCQCPP-EWTGQFCTEDVDECQLQPNACHNGGTCFNLLGGHSCVCV-NGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMG-KTGLLCHLDDACVSNPCHEDAICDTNPVSGRAICTC-PPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTFCEVDIDECQSSPCVNGGVCKDRVNGF-SCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAE-GFEGTLCERNVDDCSPDPCHH-GRCVDGIASFSCACA-PGYTGIRCESQVD 586          

HSP 5 Score: 89.7373 bits (221), Expect = 3.059e-16
Identity = 99/362 (27.35%), Postives = 141/362 (38.95%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGICQIVG-NNRICNC----TGTGFTGFDCEISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCET--PKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCN-KPICPQNYCTKNGNCLVRDDS--AVCYCDEGFTGDKCEKPI--CS--KDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKP-KPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            C+  +  C  + C+N G C   ++    C C    F G+ C++    C  + C NG   + G N   C C    TG  F   D +  +   + C N G C    G   C C    + G+ C      C    C +   C  ++V    YC C   G  G  C+    C  N C ++  C     S  A+C C  GFTG  C++ +  CS   + C + G+CV    S  C C + + G  CE     C  G C     C    G   C C              +C    C NGG+C    N F C C +  ++G  C   V  C    C+NG  C      + C C+  G+ G  C++ VD
Sbjct:  196 CENPIVPCAPSPCRNGGTCRQSSDVTYDCACLPG-FEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQ-FCTEDVDECQLQPNACHNGGTCFNLLGGHSCVCVNG-WTGESCSQNIDDCATAVCFHGATC-HDRVASF-YCAC-PMGKTGLLCHLDDACVSNPCHEDAICDTNPVSGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTFCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPS-GFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCA-EGFEGTLCERNVD 549          

HSP 6 Score: 88.9669 bits (219), Expect = 5.557e-16
Identity = 101/353 (28.61%), Postives = 139/353 (39.38%), Query Frame = 1
Query: 2113 CQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKN-GICQ---IVGNNRI-CNCTGTGFTGFDCEISR-CFNHKCQNNGIC-ILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAV-CYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSC-EKPKPCPV--GYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVGCPDNYCKNGGACEIH--RGKFGCNCSLTGYGGEQCDQKVD 3114
            C N GRC +   ++ A       + GE C ++ P C   PC   G+CQ   + G  R  C C   GF G DC +   CF+  C +   C +   G   C C    Y+G+ C +   +C       +G   +N      +C+C   G+ G  C  PI  C  + C   G C    D    C C  GF G  CE  +  C   +C+NGG CV    +  C C  ++ G+ C E    C +    C  GG C  + G   C C          +    C    C +G  C      F C C  +  TG  C     C  N C     C+ +   G+  C C   G+ G  CDQ VD
Sbjct:   50 CANGGRCTHQQPSREAACLCLPGWVGERCQLEDP-CHSGPCAGRGVCQSSVVAGVARFSCRCL-RGFRGPDCSLPDPCFSSPCAHGAPCSVGSDGRYACACPPG-YQGRNCRSDIDECRAGASCRHGGTCINTPGSF-HCLC-PLGYTGLLCENPIVPCAPSPCRNGGTCRQSSDVTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNLLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACP-MGKTGLLCHLDDACVSNPCHEDAICDTNPVSGRAICTCP-PGFTGGACDQDVD 395          

HSP 7 Score: 72.4034 bits (176), Expect = 5.545e-11
Identity = 83/289 (28.72%), Postives = 115/289 (39.79%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCEI---------SRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFC--LNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNC---LVRDD--SAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGY---------CLYGGKCRMVNGMP--RCNC 2841
            C++ V  C    CQ+ G C       + C+C  T + G+ C+     C   PC+NG  C  +  + +C+C   G  G  CEI         S     +C +NG C+   G   C+C    Y G  CE    +C    C   +   CL +       C+C   GF G RC   +  C    C   G C   L R    +  C+C + F G +CE+    C + +C  G  C    R P C C     G SC   +  P G          CL+GG C  V  +P  RC C
Sbjct: 1083 CEQEVDPCTAQPCQHGGTCRGYMGGYV-CECP-TGYSGDSCEDDVDECASQPCQNGGSCIDLVAHYLCSCP-PGTLGVLCEINEDDCGPGPSLDSGLRCLHNGTCVDLVGGFRCNCPPG-YTGLHCEADINECRPGTCHAAHTRDCLQDPGGHF-RCIC-LPGFTGPRCQTALFPCESQPCQHGGQCRPSLGRGGGLTFTCHCVQPFWGLRCERVARSCRELQCPVGIPCQQTARGPRCACPPGLSGPSCRVSRASPSGATNTSCAATPCLHGGSCLPVQSVPFFRCVC 1365          

HSP 8 Score: 69.707 bits (169), Expect = 3.932e-10
Identity = 75/267 (28.09%), Postives = 104/267 (38.95%), Query Frame = 1
Query: 2074 ACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPC--------KNGIC-QIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQ--NNGICILKQGIP-ECDCTKTVYEGQLCETPKCPLDF--CLNNGHCL--LNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCE----------KPICSKDKCINGGKCVVVDRSPF--CVCAKDFQGKSCEKPKPCP 2778
            +C+++V +C    CQN G C ++    + C C      G  C+I    C P P          NG C  +VG  R CNC   G+TG  CE  I+ C    C   +   C+   G    C C    + G  C+T   P +   C + G C   L +   L +       F+G RC +    C +  C     C        C C  G +G  C              C+   C++GG C+ V   PF  CVCA  + G  CE P   P
Sbjct: 1120 SCEDDVDECASQPCQNGGSCIDLVAHYL-CSCPPGTL-GVLCEINEDDCGPGPSLDSGLRCLHNGTCVDLVGGFR-CNCP-PGYTGLHCEADINECRPGTCHAAHTRDCLQDPGGHFRCICLPG-FTGPRCQTALFPCESQPCQHGGQCRPSLGRGGGLTFTCHCVQPFWGLRCERVARSCRELQCPVGIPCQQTARGPRCACPPGLSGPSCRVSRASPSGATNTSCAATPCLHGGSCLPVQSVPFFRCVCAPGWGGPRCETPSAAP 1381          

HSP 9 Score: 68.5514 bits (166), Expect = 7.386e-10
Identity = 107/395 (27.09%), Postives = 141/395 (35.70%), Query Frame = 1
Query: 2053 KESLFCRACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGI-----CQIVG------NNRICNCTGTGFTGFDC--EISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCE--TPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRC--NKPICPQN-------YCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKC--INGGKCVVVDRSPF-CVCAKDFQGKSCEKPK-PCPVGYCLYGGKCRMVNGMP-----RCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCS--------NVSYTGERCTNKVGCPDNYCKNGGACEIHRGK--FGCNCSLTGYGGEQCD 3102
            +E      CQ  V  C +  CQN GRC    +T   C C   ++ G  CDI    C       G+     CQ  G      ++  C C   G  G  C  E+  C    CQ+ G C    G   C+C  T Y G  CE    +C    C N G C+    + L  C     G  G  C  N+  C           C  NG C+       C C  G+TG  CE  I  C    C   +   C+      F C+C   F G  C+    PC    C +GG+CR   G        C+C Q  +  +     + C E  C  G  C        C C          VS           C    C +GG+C   +    F C C+  G+GG +C+
Sbjct:  991 REGFTGNQCQNPVDWCSQAPCQNGGRCV---QTGAYCICPP-EWSGPLCDIPSLPCTEAAAHMGVRLEQLCQAGGQCIDKDHSHYCVCP-EGRMGSHCEQEVDPCTAQPCQHGGTCRGYMGGYVCEC-PTGYSGDSCEDDVDECASQPCQNGGSCIDLVAHYLCSC---PPGTLGVLCEINEDDCGPGPSLDSGLRCLHNGTCVDLVGGFRCNCPPGYTGLHCEADINECRPGTCHAAHTRDCLQDPGGHFRCICLPGFTGPRCQTALFPCESQPCQHGGQCRPSLGRGGGLTFTCHCVQPFWGLRCERVARSCRELQCPVGIPCQQTARGPRCACPPGLSGPSCRVSRASPSGATNTSCAATPCLHGGSCLPVQSVPFFRCVCA-PGWGGPRCE 1375          
BLAST of notch-1 vs. UniProt/SwissProt
Match: sp|P07207|NOTCH_DROME (Neurogenic locus Notch protein OS=Drosophila melanogaster OX=7227 GN=N PE=1 SV=3)

HSP 1 Score: 115.546 bits (288), Expect = 4.876e-24
Identity = 112/359 (31.20%), Postives = 161/359 (44.85%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGICQIVG-NNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQ-LCETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCE-KPKPCPVGYCLYGGKCRMVNGMPRCNCT-QTNYMGX--XXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCT-NKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            CQ+ + +C  N CQ  G C +       C C+     G+ C++    C  NPC NG   I G N+  C C   GFTG  CE  +  C +  C NNG+CI +    +C+C +  Y+   L +  +C  + C+N G C  + +N+   C C   G+ G RC   I  C  N C   G C  + ++  C C  G+TG KCE  I  C  + C NGG C+       CVC   F G+ CE K  PC    C    KC   +     +CT +  Y G+    +  +      C NG  C  +   + C C+   Y G  C  N   C    C+NGG C    G + C C + G+ G+ C+  ++
Sbjct:  636 CQKQINECESNPCQFDGHCQD-RVGSYYCQCQAGT-SGKNCEVNVNECHSNPCNNGATCIDGINSYKCQCV-PGFTGQHCEKNVDECISSPCANNGVCIDQVNGYKCECPRGFYDAHCLSDVDECASNPCVNEGRCE-DGINEF-ICHC-PPGYTGKRCELDIDECSSNPCQHGGTCYDKLNAFSCQCMPGYTGQKCETNIDDCVTNPCGNGGTCIDKVNGYKCVCKVPFTGRDCESKMDPCASNRCKNEAKCTPSSNFLDFSCTCKLGYTGRYCDEDIDECSLSSPCRNGASCLNVPGSYRCLCTK-GYEGRDCAINTDDCASFPCQNGGTCLDGIGDYSCLC-VDGFDGKHCETDIN 986          

HSP 2 Score: 101.293 bits (251), Expect = 8.900e-20
Identity = 113/357 (31.65%), Postives = 155/357 (43.42%), Query Frame = 1
Query: 2071 RACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKN-GICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCT-KTVYEGQLCET--PKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRC--NKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCE-KPKPCPVGYCLYGGKC-RMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCD 3102
            + C+ ++ +C  N CQ+ G CY+      +C C    + G+ C+     C  NPC N G C    N   C C    FTG DCE  +  C +++C+N   C       +  CT K  Y G+ C+    +C L     NG   LN V     C+C + G+ G  C  N   C    C   G CL       C C +GF G  CE  I  C    C NG  C     S  C C   F G +C+   + C    CL GG C   +NG   C+C           K  KC    C NG  C   NN + C+C +  +TG++C+  V  C  + C+NG  C   + +F C CS  G+ G+ CD
Sbjct:  786 KRCELDIDECSSNPCQHGGTCYD-KLNAFSCQCMPG-YTGQKCETNIDDCVTNPCGNGGTCIDKVNGYKCVCK-VPFTGRDCESKMDPCASNRCKNEAKCTPSSNFLDFSCTCKLGYTGRYCDEDIDECSLSSPCRNGASCLN-VPGSYRCLC-TKGYEGRDCAINTDDCASFPCQNGGTCLDGIGDYSCLCVDGFDGKHCETDINECLSQPCQNGATCSQYVNSYTCTCPLGFSGINCQTNDEDCTESSCLNGGSCIDGINGY-NCSCLAGYSGANCQYKLNKCDSNPCLNGATCHEQNNEYTCHCPS-GFTGKQCSEYVDWCGQSPCENGATCSQMKHQFSCKCS-AGWTGKLCD 1134          

HSP 3 Score: 91.6633 bits (226), Expect = 9.221e-17
Identity = 108/355 (30.42%), Postives = 146/355 (41.13%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKN-GICQIVGNNRICNCTGTGFTGFDCEIS--RCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            C+ N+ +C  + CQN+G C +   T   C C    F G  C+I    C  NPC N G C    N   C+C   GFTG  C+I+   C +  C+N GIC        C+C    Y G  CE     C  + C + G C+ + VN    C+C+  G+ GY C K I  C  N C  +G+C  R  S  C C  G +G  CE  +  C  + C NG  C+    S  C C   F G+ CEK     V  C+                                    C N G+C    N + C C    Y     ++   C  N C N G CE    +F C+C   GY G++C+  +D
Sbjct:  485 CETNINECESHPCQNEGSCLDDPGT-FRCVCMPG-FTGTQCEIDIDECQSNPCLNDGTCHDKINGFKCSCA-LGFTGARCQINIDDCQSQPCRNRGICHDSIAGYSCECPPG-YTGTSCEININDCDSNPC-HRGKCI-DDVNSFK-CLCDP-GYTGYICQKQINECESNPCQFDGHCQDRVGSYYCQCQAGTSGKNCEVNVNECHSNPCNNGATCIDGINSYKCQCVPGFTGQHCEKN----VDECI---------------------------------SSPCANNGVCIDQVNGYKCECPRGFYDAHCLSDVDECASNPCVNEGRCEDGINEFICHCP-PGYTGKRCELDID 793          

HSP 4 Score: 87.8113 bits (216), Expect = 1.064e-15
Identity = 106/356 (29.78%), Postives = 143/356 (40.17%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKN-GICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRM--VNGMPRCNCTQTNYMGX--XXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERC-TNKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            C  ++++C  N C+  G C N + +   C C  T + G+ CD K   C P+PC+N GIC+  G +  C C   GF G +CE     C  H CQN G CI       C C    + G+ C+     +D C    H                          P+C QN  T    C     S  C C  G+ G  C      C +  C  G  C+    S +C C K   G  C     C    C     C    +NG   C+C  T Y G     +  +      CE+ GIC      + CNCS   +TG RC TN   C  + C+N G+C    G F C C + G+ G QC+  +D
Sbjct:  214 CSYDIEECQSNPCKYGGTCVNTHGS-YQCMC-PTGYTGKDCDTKYKPCSPSPCQNGGICRSNGLSYECKCP-KGFEGKNCEQNYDDCLGHLCQNGGTCIDGISDYTCRCPPN-FTGRFCQD---DVDECAQRDH--------------------------PVC-QNGAT----CTNTHGSYSCICVNGWAGLDCSNNTDDCKQAACFYGATCIDGVGSFYCQCTKGKTGLLCHLDDACTSNPCHADAICDTSPINGSYACSCA-TGYKGVDCSEDIDECDQGSPCEHNGICVNTPGSYRCNCSQ-GFTGPRCETNINECESHPCQNEGSCLDDPGTFRCVC-MPGFTGTQCEIDID 528          

HSP 5 Score: 82.4185 bits (202), Expect = 4.517e-14
Identity = 108/350 (30.86%), Postives = 146/350 (41.71%), Query Frame = 1
Query: 2089 VKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNR----ICNCTGTGFTGFDCEIS---RCFNHKCQNNGICILKQGIPECDCT-KTVYEGQLCETPK-CPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCE---KPICSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGY-CLYGGKCRMVNGMPRCNCT-QTNYMGX----XXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKV-GCPDNYCKNGGACEIHRGKFGCNCS 3072
               C    CQN G C      K  C C  + + G++C+ + P C+   C+NG  CQ+   N      C C   GF    CEI+    C +  C N G C LK  + E  C     Y G+ CET   C    C N   C     +    C C   GF G  C+  I  C  N C   G C+    S  C C  G+TG  C+   KP CS   C NGG C     S  C C K F+GK+CE+     +G+ C  GG C  ++G+    C    N+ G+      ++  +     C+NG  C+  +  + C C N  + G  C+N    C    C  G  C    G F C C+
Sbjct:   59 AASCTSVGCQNGGTCVTQLNGKTYCACD-SHYVGDYCEHRNP-CNSMRCQNGGTCQVTFRNGRPGISCKCP-LGFDESLCEIAVPNACDHVTCLNGGTCQLKT-LEEYTCACANGYTGERCETKNLCASSPCRNGATCTALAGSSSFTCSC-PPGFTGDTCSYDIEECQSNPCKYGGTCVNTHGSYQCMCPTGYTGKDCDTKYKP-CSPSPCQNGGICRSNGLSYECKCPKGFEGKNCEQNYDDCLGHLCQNGGTC--IDGISDYTCRCPPNFTGRFCQDDVDECAQRDHPVCQNGATCTNTHGSYSCICVN-GWAGLDCSNNTDDCKQAACFYGATCIDGVGSFYCQCT 399          

HSP 6 Score: 82.4185 bits (202), Expect = 4.555e-14
Identity = 102/356 (28.65%), Postives = 134/356 (37.64%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYN-INETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCE-KPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGA--CEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            CQ N + C ++ C N G C + IN    +C      + G  C  K   CD NPC NG  C    N   C+C  +GFTG  C   +  C    C+N   C   +    C C+   + G+LC+          +     L Q+                 CN           NG C    +S VCYC +G+ G  C+K I  C    C NGG C  +  +  C C + FQG++CE     C    C  GG C        C+C               C    C N G C      F C C    + G RC   +  C  N C N G   C      + CNC   G+ G  C+ KVD
Sbjct: 1019 CQTNDEDCTESSCLNGGSCIDGINGYNCSC---LAGYSGANCQYKLNKCDSNPCLNGATCHEQNNEYTCHCP-SGFTGKQCSEYVDWCGQSPCENGATCSQMKHQFSCKCSAG-WTGKLCDVQTISCQDAADRKGLSLRQL-----------------CN-----------NGTCKDYGNSHVCYCSQGYAGSYCQKEIDECQSQPCQNGGTCRDLIGAYECQCRQGFQGQNCELNIDDCAPNPCQNGGTCHDRVMNFSCSCPPGTMGIICEINKDDCKPGACHNNGSCIDRVGGFECVCQ-PGFVGARCEGDINECLSNPCSNAGTLDCVQLVNNYHCNCR-PGHMGRHCEHKVD 1339          

HSP 7 Score: 82.0333 bits (201), Expect = 6.429e-14
Identity = 83/254 (32.68%), Postives = 111/254 (43.70%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCEISR--CFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCE--KPICSKDKCINGGKCVVVDR--SPFCVCAKDFQGKSCE-------KPKPCPVG 2784
            CQ+ + +C    CQN G C ++      C C++  F G+ C++    C PNPC+NG  C     N  C+C   G  G  CEI++  C    C NNG CI + G  EC C +  + G  CE    +C  + C N G     Q+    +C C   G  G  C   +  C Q+ C   GNC +R     C C+ GF G  CE     C  + C   G CVV D      C C +   G+ CE        P PC  G
Sbjct: 1180 CQKEIDECQSQPCQNGGTCRDL-IGAYECQCRQG-FQGQNCELNIDDCAPNPCQNGGTCHDRVMNFSCSCP-PGTMGIICEINKDDCKPGACHNNGSCIDRVGGFECVC-QPGFVGARCEGDINECLSNPCSNAGTLDCVQLVNNYHCNCRP-GHMGRHCEHKVDFCAQSPCQNGGNCNIRQSGHHCICNNGFYGKNCELSGQDCDSNPC-RVGNCVVADEGFGYRCECPRGTLGEHCEIDTLDECSPNPCAQG 1427          

HSP 8 Score: 76.6406 bits (187), Expect = 3.173e-12
Identity = 111/363 (30.58%), Postives = 143/363 (39.39%), Query Frame = 1
Query: 2071 RACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSC---DPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCE-TPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNY-CTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCE-KPKPCPVGYCLYGGKCR-MVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCT-NKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            + C++N   C  + CQN G C +   +   C C    F G FC      C   D   C+NG  C     +  C C   G+ G DC      C    C     CI   G   C CTK    G LC     C  + C  +  C  + +N    C C +TG+ G  C++ I  C Q   C  NG C+    S  C C +GFTG +CE  I  C    C N G C+    +  CVC   F G  CE     C    CL  G C   +NG  +C+C       +       C  + C N GIC      + C C    YTG  C  N   C  N C   G C      F C C   GY G  C ++++
Sbjct:  288 KNCEQNYDDCLGHLCQNGGTCID-GISDYTCRCPPN-FTGRFCQDDVDECAQRDHPVCQNGATCTNTHGSYSCICV-NGWAGLDCSNNTDDCKQAACFYGATCIDGVGSFYCQCTKG-KTGLLCHLDDACTSNPCHADAICDTSPINGSYACSC-ATGYKGVDCSEDIDECDQGSPCEHNGICVNTPGSYRCNCSQGFTGPRCETNINECESHPCQNEGSCLDDPGTFRCVCMPGFTGTQCEIDIDECQSNPCLNDGTCHDKINGF-KCSCALGFTGARCQINIDDCQSQPCRNRGICHDSIAGYSCECP-PGYTGTSCEININDCDSNPCHR-GKCIDDVNSFKCLCD-PGYTGYICQKQIN 641          
BLAST of notch-1 vs. UniProt/SwissProt
Match: sp|P21783|NOTC1_XENLA (Neurogenic locus notch homolog protein 1 OS=Xenopus laevis OX=8355 GN=notch1 PE=1 SV=3)

HSP 1 Score: 114.39 bits (285), Expect = 1.140e-23
Identity = 110/369 (29.81%), Postives = 161/369 (43.63%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETK-IACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRC--NKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEK-PKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMG-----------XXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            C+  +  C  + C+N GRC    + +  +C+C    + G+ C+I    C   PC+NG  CQ    +  CNC   G+TG +CE  I  C  + C N G C     +  C+C    + G  CE    +C  + C N  +C  + VN    C C   GF G  C  N P C ++ C   G C+   ++  C C  GFTG  C+  I  C    C+NGG C     +  C C + + G +C+   + C    C  GGKC   N   RC C ++ + G              ++        C N G+C    N   C C    YTG  C  +V  C  N C+NG  C  + G + C C + GY G  C ++++
Sbjct:  825 CEAVLAPCAGSPCKNGGRCKESEDFETFSCECPPG-WQGQTCEIDMNECVNRPCRNGATCQNTNGSYKCNCK-PGYTGRNCEMDIDDCQPNPCHNGGSCSDGINMFFCNC-PAGFRGPKCEEDINECASNPCKNGANCT-DCVNSY-TCTC-QPGFSGIHCESNTPDCTESSCFNGGTCIDGINTFTCQCPPGFTGSYCQHDINECDSKPCLNGGTCQDSYGTYKCTCPQGYTGLNCQNLVRWCDSSPCKNGGKCWQTNNFYRCEC-KSGWTGVYCDVPSVSCEVAAKQQGVDIVHLCRNSGMCVDTGNTHFCRCQ-AGYTGSYCEEQVDECSPNPCQNGATCTDYLGGYSCEC-VAGYHGVNCSEEIN 1184          

HSP 2 Score: 98.9821 bits (245), Expect = 4.878e-19
Identity = 106/340 (31.18%), Postives = 144/340 (42.35%), Query Frame = 1
Query: 2113 CQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKN-GICQIV--GN--NRICNCTGTGFTGFDCEI---SRCFNHKCQNNGICILKQGIPECDCT-KTVYEGQLCETPK-CPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPF-CVCAKDFQGKSCEKP-KPCPVGYCLYGGKCRMVNGMPRCNCT----QTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKV-GCPDNYCKNGGACEIHRGKFGCNC 3069
            C N GRC         C C    ++GE C    P    N C N G C+ V  GN  + IC+C   GFT   C     + C N+ C+N G C L   + E  C     + G  C+    C  + C N G CL  ++  +  C     GF+G  C + I  C QN C   G C+    S  C C   FTG  C++P   C+   C+NGG C   D + + C C   F G++CE+    CP   C  GG C  V+G+   NC      T     +     +     C+NGG C      + C C N  +TGE C+  +  C +  C +G  C      F C C
Sbjct:   29 CLNGGRCEMTPGGTGVCLCGNL-YFGERCQFPNPCTIKNQCMNFGTCEPVLQGNAIDFICHCP-VGFTDKVCLTPVDNACVNNPCRNGGTCELLNSVTEYKCRCPPGWTGDSCQQADPCASNPCANGGKCLPFEIQYICKC---PPGFHGATCKQDINECSQNPCKNGGQCINEFGSYRCTCQNRFTGRNCDEPYVPCNPSPCLNGGTCRQTDDTSYDCTCLPGFSGQNCEENIDDCPSNNCRNGGTC--VDGVNTYNCQCPPDWTGQYCTEDVDECQLMPNACQNGGTCHNTYGGYNCVCVN-GWTGEDCSENIDDCANAACHSGATCHDRVASFYCEC 360          

HSP 3 Score: 91.6633 bits (226), Expect = 8.445e-17
Identity = 114/358 (31.84%), Postives = 146/358 (40.78%), Query Frame = 1
Query: 2098 CPKNYCQNKGRCYNINE-TKIACDCKKTQFYGEFCDIKRPSCDPNPCKN-GICQIVGNNRICNCTGTGFTGFDC--EISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCPLD--FCLNNGHCLLNQVNQLPY-CVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI----CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSC-EKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSI--INNVFICNCSNVSYTGERCTNKV---GCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            C  N C+N G C  +N  T+  C C    + G+ C    P C  NPC N G C       IC C   GF G  C  +I+ C  + C+N G CI + G   C C +  + G+ C+ P  P +   CLN G C   Q +   Y C C   GF G  C + I  CP N C   G C+   ++  C C   +TG  C + +       + C NGG C        CVC   + G+ C E    C    C  G  C        C C      G  C     C    C  G  C    +N   IC C    YTG  C N V       N C++GG C    G F CNC   GY G +C+  V+
Sbjct:  106 CVNNPCRNGGTCELLNSVTEYKCRCPPG-WTGDSCQQADP-CASNPCANGGKCLPFEIQYICKCP-PGFHGATCKQDINECSQNPCKNGGQCINEFGSYRCTC-QNRFTGRNCDEPYVPCNPSPCLNGGTC--RQTDDTSYDCTC-LPGFSGQNCEENIDDCPSNNCRNGGTCVDGVNTYNCQCPPDWTGQYCTEDVDECQLMPNACQNGGTCHNTYGGYNCVCVNGWTGEDCSENIDDCANAACHSGATCHDRVASFYCECPH-GRTGLLCHLDNACISNPCNEGSNCDTNPVNGKAICTCP-PGYTGPACNNDVDECSLGANPCEHGGRCTNTLGSFQCNCP-QGYAGPRCEIDVN 453          

HSP 4 Score: 87.0409 bits (214), Expect = 2.186e-15
Identity = 109/366 (29.78%), Postives = 156/366 (42.62%), Query Frame = 1
Query: 2056 ESLFCRACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCE--KPICSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKP-KPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINN--VFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            E    R C++++ +C  + C   G C +   T   C C+   + G  CD     C   PC NG  C    N  IC C   G TG +CE  I  C ++ C +NG CI K    EC C +  Y G+LC     +C  + C N G C  +Q+N    CVC   G++ + C   +  C  N C  +G C    +   C C+ G++G  C+     C  + C+NGG C  +  +  C C   F G +C+     C    CL  G C       +CNC               C    C+NGG C    +   F C C    + G+ C   +  C +  C+NG  C+   G + CNC   GY G  C+  +D
Sbjct:  555 EGFTGRHCEQDINECIPDPCH-YGTCKDGIAT-FTCLCRPG-YTGRLCDNDINECLSKPCLNGGQCTDRENGYICTCP-KGTTGVNCETKIDDCASNLC-DNGKCIDKIDGYECTC-EPGYTGKLCNININECDSNPCRNGGTCK-DQINGF-TCVC-PDGYHDHMCLSEVNECNSNPCI-HGACHDGVNGYKCDCEAGWSGSNCDINNNECESNPCMNGGTCKDMTGAYICTCKAGFSGPNCQTNINECSSNPCLNHGTCIDDVAGYKCNCMLPYTGAICEAVLAPCAGSPCKNGGRCKESEDFETFSCECP-PGWQGQTCEIDMNECVNRPCRNGATCQNTNGSYKCNCK-PGYTGRNCEMDID 908          

HSP 5 Score: 86.6557 bits (213), Expect = 2.608e-15
Identity = 101/316 (31.96%), Postives = 140/316 (44.30%), Query Frame = 1
Query: 2200 DIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCEI--SRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCET--PKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKP-KPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            D+   S   NPC++G  C     +  CNC   G+ G  CEI  + C ++ CQN+  C+ + G  +C C    YEG  CET   +C  + CL+NG C+ +++N+   C C  TGF G  C      C    C     CL   +S  C C EGFTG  CE+ I  C  D C + G C     +  C+C   + G+ C+     C    CL GG+C        C C +         K   C    C+NG     I+  + C C    YTG+ C   +  C  N C+NGG C+     F C C   GY    C  +V+
Sbjct:  411 DVDECSLGANPCEHGGRCTNTLGSFQCNCP-QGYAGPRCEIDVNECLSNPCQNDSTCLDQIGEFQCICMPG-YEGLYCETNIDECASNPCLHNGKCI-DKINEF-RCDC-PTGFSGNLCQHDFDECTSTPCKNGAKCLDGPNSYTCQCTEGFTGRHCEQDINECIPDPC-HYGTCKDGIATFTCLCRPGYTGRLCDNDINECLSKPCLNGGQCTDRENGYICTCPKGTTGVNCETKIDDCASNLCDNGKCIDKIDG-YECTCE-PGYTGKLCNININECDSNPCRNGGTCKDQINGFTCVCP-DGYHDHMCLSEVN 717          

HSP 6 Score: 85.1149 bits (209), Expect = 7.333e-15
Identity = 110/386 (28.50%), Postives = 149/386 (38.60%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFC--DIKRPSCDPNPCKN-GICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETP-KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI----CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKP-KPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKV---------DGVMCDYKEPGYAITAFK 3165
            C+EN+  CP N C+N G C +   T   C C    + G++C  D+      PN C+N G C        C C   G+TG DC   I  C N  C +   C  +     C+C      G LC     C  + C    +C  N VN    C C   G+ G  CN  +       N C   G C     S  C C +G+ G +CE  +  C  + C N   C+       C+C   ++G  CE     C    CL+ GKC       RC+C              +C    C+NG  C    N + C C+   +TG  C   +  C  + C   G C+     F C C   GY G  CD  +         +G  C  +E GY  T  K
Sbjct:  253 CEENIDDCPSNNCRNGGTCVDGVNT-YNCQCPP-DWTGQYCTEDVDECQLMPNACQNGGTCHNTYGGYNCVCV-NGWTGEDCSENIDDCANAACHSGATCHDRVASFYCECPHG-RTGLLCHLDNACISNPCNEGSNCDTNPVNGKAICTC-PPGYTGPACNNDVDECSLGANPCEHGGRCTNTLGSFQCNCPQGYAGPRCEIDVNECLSNPCQNDSTCLDQIGEFQCICMPGYEGLYCETNIDECASNPCLHNGKCIDKINEFRCDCPTGFSGNLCQHDFDECTSTPCKNGAKCLDGPNSYTCQCTE-GFTGRHCEQDINECIPDPCHY-GTCKDGIATFTCLCR-PGYTGRLCDNDINECLSKPCLNGGQCTDRENGYICTCPK 630          

HSP 7 Score: 84.3445 bits (207), Expect = 1.194e-14
Identity = 88/308 (28.57%), Postives = 122/308 (39.61%), Query Frame = 1
Query: 2107 NYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDC--EISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCE---------------TPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNG--NCLVRDDSAVCYCDEGFTGDKCEKPI-------------------------------------------CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKP--KPCPVGYCLYGGKCRMVNGMP 2829
            + C+N G C +   T   C C+   + G +C+ +   C PNPC+NG  C        C C   G+ G +C  EI+ C +H CQN G CI      +C C +   +G  CE                PKC      NNG C+ ++V     C+C   GF G RC   +  C  N C   G  NC+   +   C C +GFTG +CE  +                                           CS  +C NGG C+ V  S  CVC++ + G +C+ P   PC    C  GG C+     P
Sbjct: 1113 HLCRNSGMCVDTGNTHF-CRCQ-AGYTGSYCEEQVDECSPNPCQNGATCTDYLGGYSCECVA-GYHGVNCSEEINECLSHPCQNGGTCIDLINTYKCSCPRGT-QGVHCEINVDDCTPFYDSFTLEPKC-----FNNGKCI-DRVGGY-NCIC-PPGFVGERCEGDVNECLSNPCDSRGTQNCIQLVNDYRCECRQGFTGRRCESVVDGCKGMPCRNGGTCAVASNTERGFICKCPPGFDGATCEYDSRTCSNLRCQNGGTCISVLTSSKCVCSEGYTGATCQYPVISPCASHPCYNGGTCQFFAEEP 1408          

HSP 8 Score: 83.9593 bits (206), Expect = 1.896e-14
Identity = 110/365 (30.14%), Postives = 153/365 (41.92%), Query Frame = 1
Query: 2074 ACQENVKKCPKNYCQNKGRCYNINE-TKIACDCKKTQFYGEFCDIKRPSCDPNPCKN-GICQIVGNNRI-CNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLC--ETPKCPL--DFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCE-KPICSKDKCINGGKCVV--VDRSPFCVCAKDFQGKSCEKP-KPCPVGY--CLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERC-TNKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
             C++++ +C +N C+N G+C  INE     C C+  +F G  CD     C+P+PC N G C+   +    C C   GF+G +CE  I  C ++ C+N G C+       C C    + GQ C  +  +C L  + C N G C  +       CVC   G+ G  C++ I  C    C     C  R  S  C C  G TG  C     C  + C  G  C    V+    C C   + G +C      C +G   C +GG+C    G  +CNC Q     +      +C    C+N   C      F C C    Y G  C TN   C  N C + G C     +F C+C  TG+ G  C    D
Sbjct:  175 TCKQDINECSQNPCKNGGQC--INEFGSYRCTCQN-RFTGRNCDEPYVPCNPSPCLNGGTCRQTDDTSYDCTCL-PGFSGQNCEENIDDCPSNNCRNGGTCVDGVNTYNCQCPPD-WTGQYCTEDVDECQLMPNACQNGGTC--HNTYGGYNCVC-VNGWTGEDCSENIDDCANAACHSGATCHDRVASFYCECPHGRTGLLCHLDNACISNPCNEGSNCDTNPVNGKAICTCPPGYTGPACNNDVDECSLGANPCEHGGRCTNTLGSFQCNCPQGYAGPRCEIDVNECLSNPCQNDSTCLDQIGEFQCICM-PGYEGLYCETNIDECASNPCLHNGKCIDKINEFRCDCP-TGFSGNLCQHDFD 529          

HSP 9 Score: 80.1073 bits (196), Expect = 2.611e-13
Identity = 109/378 (28.84%), Postives = 147/378 (38.89%), Query Frame = 1
Query: 2071 RACQENVKKCPKNYCQNKGRCYN-INETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGI-CQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPY-CVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKP-----ICSKDK-------CINGGKCVVVDRSPFCVCAKDFQGKSCEKP-KPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVGCPDNY--------CKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            R C+ ++  C  N C N G C + IN     C+C    F G  C+     C  NPCKNG  C    N+  C C   GF+G  CE     C    C N G CI       C C    + G  C+    +C    CLN G C   Q +   Y C C   G+ G  C   +  C  + C   G C   ++   C C  G+TG  C+ P     + +K +       C N G CV    + FC C   + G  CE+    C    C  G  C    G   C C    +     E+  +C    C+NGG C  + N + C+C   +       N   C   Y        C N G C    G + C C   G+ GE+C+  V+
Sbjct:  901 RNCEMDIDDCQPNPCHNGGSCSDGIN--MFFCNC-PAGFRGPKCEEDINECASNPCKNGANCTDCVNSYTCTCQ-PGFSGIHCESNTPDCTESSCFNGGTCIDGINTFTCQCPPG-FTGSYCQHDINECDSKPCLNGGTC---QDSYGTYKCTC-PQGYTGLNCQNLVRWCDSSPCKNGGKCWQTNNFYRCECKSGWTGVYCDVPSVSCEVAAKQQGVDIVHLCRNSGMCVDTGNTHFCRCQAGYTGSYCEEQVDECSPNPCQNGATCTDYLGGYSCECVAGYHGVNCSEEINECLSHPCQNGGTCIDLINTYKCSCPRGTQGVHCEINVDDCTPFYDSFTLEPKCFNNGKCIDRVGGYNCICP-PGFVGERCEGDVN 1268          

HSP 10 Score: 75.485 bits (184), Expect = 5.902e-12
Identity = 110/367 (29.97%), Postives = 139/367 (37.87%), Query Frame = 1
Query: 2074 ACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKN-GICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIP-ECDCTKTVYEGQLCET--PKCPLDFCLNNGHCL--LNQVNQLPYCVCNSTGFYGYRCNKPI----CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRM--VNGMPRCNCTQTNYMGXX---XXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            +CQ+    C  N C N G+C    E +  C C    F+G  C      C  NPCKN G C     +  C C    FTG +C+     C    C N G C        +C C    + GQ CE     CP + C N G C+  +N  N    C C    + G  C + +       N C   G C        C C  G+TG+ C + I  C+   C +G  C     S +C C     G  C     C    C  G  C    VNG   C C    Y G                CE+GG C+     F CNC    Y G RC   V  C  N C+N   C    G+F C C + GY G  C+  +D
Sbjct:  138 SCQQ-ADPCASNPCANGGKCLPF-EIQYICKCPPG-FHGATCKQDINECSQNPCKNGGQCINEFGSYRCTCQNR-FTGRNCDEPYVPCNPSPCLNGGTCRQTDDTSYDCTCLPG-FSGQNCEENIDDCPSNNCRNGGTCVDGVNTYN----CQC-PPDWTGQYCTEDVDECQLMPNACQNGGTCHNTYGGYNCVCVNGWTGEDCSENIDDCANAACHSGATCHDRVASFYCECPHGRTGLLCHLDNACISNPCNEGSNCDTNPVNGKAICTCP-PGYTGPACNNDVDECSLGANPCEHGGRCTNTLGSFQCNCPQ-GYAGPRCEIDVNECLSNPCQNDSTCLDQIGEFQCIC-MPGYEGLYCETNID 491          
BLAST of notch-1 vs. UniProt/SwissProt
Match: sp|Q8TER0|SNED1_HUMAN (Sushi, nidogen and EGF-like domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SNED1 PE=2 SV=2)

HSP 1 Score: 112.464 bits (280), Expect = 3.476e-23
Identity = 122/404 (30.20%), Postives = 161/404 (39.85%), Query Frame = 1
Query: 2071 RACQENVKKCPKNYCQNKGRC-YNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCPL-DFCL-----NNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI-----------------------------------------CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKP--CPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXX--XXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCT-NKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            R C  +V +C    CQN G C + IN  +  C      F G  C+  +  CD   C++G  CQ+   + +C C   G+TG  CE  +  C    C N G C+   G   C C +  ++G  CET   P+ D CL     N G C+    +Q   C C   GF G  C + +     C   G CL   ++ +C C  GF G  CE  I                                         C  D C NGG C   D S  C C + F GK CEK +P  C  G C  GG C+   G   C+C    + G+     KP  C    C NGG C      + C+C    ++G  C      C  + C NGG CE     F C+C   GY G +C  +VD
Sbjct:  306 RRCHLDVNECASQPCQNGGTCTHGINSFRCQC---PAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQ-AGYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEP-FKGLRCETGDHPVPDACLSAPCHNGGTCV--DADQGYVCEC-PEGFMGLDCRERVPDDCECRNGGRCLGA-NTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPY-RFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCP-PGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQ-AGYMGRRCQAEVD 697          

HSP 2 Score: 80.4925 bits (197), Expect = 1.748e-13
Identity = 92/362 (25.41%), Postives = 135/362 (37.29%), Query Frame = 1
Query: 2098 CPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPS-CDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCEISR---CFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCP--LDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNK-----PICPQNYCTKNGNCLVRDDSAVCYCDEGFT-------------GDKCEKPIC------SKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKV-GCPDNYCKNGGACEIHRGKFGCNCSLTGYG 3087
            C  + C N G C + ++    C+C +  F+G+ C+  RP  C   PC+NG  C+  G    C+C    FTG  CEI +   C +  C N G C    G  +CDC    + G+ CE    P     C+N G C     +   +C     G+ G RC       P     + T   N       A+  CD G++             G   E P C          C++GG C        C+C+  ++G  CE          L   +CR                              C NGG C  +   ++C C    + G  C  +V  C  + C++GG CE   G + C C  + +G
Sbjct:  545 CDSDPCFNGGSC-DAHDDSYTCECPRG-FHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCP-YRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPG-FSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHC---QAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCE----------LERDECRA---------------------------HPCRNGGSCRNLPGAYVCRCP-AGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESFFG 861          

HSP 3 Score: 75.0998 bits (183), Expect = 6.678e-12
Identity = 75/243 (30.86%), Postives = 106/243 (43.62%), Query Frame = 1
Query: 2443 LDFCLNNGHCLLNQVNQLPYCVCNS-TGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCE--KPICSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKP-KPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXX-----XXYCENGGICSIINNVFICNCSNVSYTGERCTNKVGCPDN-YCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVDGVMCDYK 3135
            L  CLN G C+ + V   P   C+  +GF G RC+  +  C    C   G C    +S  C C  GF G  CE  +  C   +C +GG+C V + S  CVC   + G +CE     C    CL GG C  + G   C C +  + G +CE              C NGG C   +  ++C C    + G  C  +V  PD+  C+NGG C       G N +L      QC     G++C+++
Sbjct:  275 LRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEP-FKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGYVCECPE-GFMGLDCRERV--PDDCECRNGGRC------LGANTTLC-----QCPLGFFGLLCEFE 502          

HSP 4 Score: 68.9366 bits (167), Expect = 5.175e-10
Identity = 90/349 (25.79%), Postives = 126/349 (36.10%), Query Frame = 1
Query: 2113 CQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPC-------KNGICQIVGNNRICNCTGTGFTGFDCEISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPK---CPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCN--KP-ICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCE--KPICSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            C+N GRC   N T   C      F+G  C+ +  +    PC         G C   G + +C C  T         S C +  C N G C        C+C +  + G+ CE  +   C    C N G C   +     +C C    F G  C   KP  C    C   G C        C C  GF+G  CE     C +  C+NGG C   D   FC C   + G+ C+    C       G    + +   R N T+   +              C+ G   S  + + +C    V     +C     C    C +GG+C+     + C CS TGY G  C+ + D
Sbjct:  474 CRNGGRCLGANTTLCQC---PLGFFGLLCEFEITA---MPCNMNTQCPDGGYCMEHGGSYLCVCH-TDHNASHSLPSPCDSDPCFNGGSCDAHDDSYTCECPRG-FHGKHCEKARPHLCSSGPCRNGGTC--KEAGGEYHCSCPYR-FTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDC-------GPPEEVKHATLRFNGTRLGAVALYA----------CDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCS-TGYEGAHCELERD 793          

HSP 5 Score: 67.781 bits (164), Expect = 1.297e-9
Identity = 80/286 (27.97%), Postives = 110/286 (38.46%), Query Frame = 1
Query: 2095 KCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCEIS-------RCFNHKCQNNGICILKQGIPECDCTKTVY----------EGQLCETPKCPLDF-------CLNNGHCLLNQVNQLPYCVCNSTGFYGYRCN--KPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEK-PKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMG 2862
             C    C N G C++    K  CDC    F G  C+I    C  +PC NG  C+    +  C+C   G+ G  C+            +   + NG  +    +  CD   ++            G   E P+C L+        CL+ G C       L  C+C STG+ G  C   +  C  + C   G+C     + VC C  GF G  CE  +  C    C +GG+C     +  CVC + F G  CE    PC    C   G C   NG   C C +  Y G
Sbjct:  622 SCASGPCHNGGTCFHYI-GKYKCDCPPG-FSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQ-AGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQC-LEIDECRSQPCLHGGSCQDRVAGYL--CLC-STGYEGAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTC-KVGYTG 899          

HSP 6 Score: 56.9954 bits (136), Expect = 2.617e-6
Identity = 52/155 (33.55%), Postives = 66/155 (42.58%), Query Frame = 1
Query: 2218 CDPNPC-KNGICQIVGNNRICNCTGTGFTGFDCEISR--CFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCN--KPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI 2661
            C   PC   G CQ      +C C+ TG+ G  CE+ R  C  H C+N G C    G   C C    + G  CET    C    C + G C       L  CVC  + F+GY C      C  + C   G CL  + S  C C  G+TG+ C K +
Sbjct:  757 CRSQPCLHGGSCQDRVAGYLCLCS-TGYEGAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAG-FVGVHCETEVDACDSSPCQHGGRCESGGGAYL--CVCPES-FFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKEL 906          
BLAST of notch-1 vs. UniProt/SwissProt
Match: sp|Q9UM47|NOTC3_HUMAN (Neurogenic locus notch homolog protein 3 OS=Homo sapiens OX=9606 GN=NOTCH3 PE=1 SV=2)

HSP 1 Score: 112.464 bits (280), Expect = 4.110e-23
Identity = 110/402 (27.36%), Postives = 164/402 (40.80%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICI--LKQGIPECDCTKTVYEGQL----CETPKCPLDFC---LNNGHCLLNQVNQLPYC-----VCNST----------GFYGYRCN------KPIC--PQNYCT----KNGNCLVRDDSAVCYCDEGFTGDKCEKPI----CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRMVNG-MPRCNCTQTNYMGXXXXXXXXXXX--XYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVDGVMCDYKEPG 3144
            CQ +V +C    C+N  +C +       C C +  F G  CD     C P+PC +G C     +  C C   G+TG  CE  +  C +  C++ G C+  + + +  C    T    ++    C +  C    C   +N   C+       P C      C S+          G  G+RC        P+C  P + C      +G C        C C+ G++G +C + +    C    C  GG C        C C    QG+ CE   PC    C +GG+C    G +P C+C Q  + G +C++          C   GIC+ +   F C C    YTG  C   +  C  N C NGG+C+   G F C+C L G+ G +C + VD  + +   PG
Sbjct:  504 CQLDVDECASTPCRNGAKCVD-QPDGYECRCAEG-FEGTLCDRNVDDCSPDPCHHGRCVDGIASFSCAC-APGYTGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQ-GWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHG-GYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSC-LPGFAGPRCARDVDECLSNPCGPG 899          

HSP 2 Score: 98.9821 bits (245), Expect = 5.123e-19
Identity = 108/401 (26.93%), Postives = 154/401 (38.40%), Query Frame = 1
Query: 2071 RACQENVKKCPKNY-CQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKN-GICQIVGN-NRICNCTGTGFTGFDCEIS--RCFNHKCQNNGICILKQGIPECDCTKTVYEGQLC--ETPKCPL--DFCLNNGHCLLNQVNQLPYCVCNSTG---------------FYGYRCNKPI---------------------CPQNYCTKNGNCLVR--DDSAVCYCDEGFTGDKCEKPI--CS--KDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKP-KPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            R+C+ +V +C     C++ G C N       C C    + G  C+     C P+PC+N G C+  G+    C C   GF G +CE++   C  H+C N G C+       C C    + GQ C  +  +C L  + C N G C          CV   TG               F+G  C+  +                     C  N C ++  C     +  A+C C  GFTG  C++ +  CS   + C + G+CV    S  C C + + G  CE     C  G C     C    G   C C              +C    C NGG+C    N F C C +  ++G  C   V  C    C+NG  C      + C C+  G+ G  CD+ VD
Sbjct:  153 RSCRSDVDECRVGEPCRHGGTCLN-TPGSFRCQCP-AGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACL-PGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPE-WTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPS-GFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCA-EGFEGTLCDRNVD 547          

HSP 3 Score: 94.7449 bits (234), Expect = 9.811e-18
Identity = 104/361 (28.81%), Postives = 139/361 (38.50%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFC--DIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCE-TPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI----CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCE-KPKPCPVGYCLYGGKCR-MVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKV-GCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            C+ NV  CP + C N G C +   T   C C   ++ G+FC  D+      PN C NG  C        C C   G+TG  C   I  C    C +   C  +     C C      G LC     C  + C  +  C  N VN    C C   GF G  C++ +       N C   G C+    S +C C  G+TG +CE  +  C    C N   C+       C+C   F G  CE     C    C+ GG C+  VNG   C C              +C    C NG  C    + + C C+   + G  C   V  C  + C + G C      F C C+  GY G +C+ +VD
Sbjct:  233 CEVNVDDCPGHRCLNGGTCVDGVNT-YNCQCPP-EWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCV-NGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMG-KTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTC-PPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGF-SCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAE-GFEGTLCDRNVDDCSPDPCHH-GRCVDGIASFSCACA-PGYTGTRCESQVD 584          

HSP 4 Score: 90.8929 bits (224), Expect = 1.254e-16
Identity = 99/373 (26.54%), Postives = 146/373 (39.14%), Query Frame = 1
Query: 2074 ACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLC--ETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCE-KPICSKDK-----------CINGGKCVVVDRSPFCVCAKDFQGKSCEKP-KPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVGCPDN-------YCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            +C +++  C  N C N G C +      +C C    F G  C      C  NPC  G C     +  C C   G+ GF CE  +  C    C N G C+       C C +  Y G  C  E   C    CL+ G C  +  +    C C  + F G +C   +  C +  C   G C+     A C C  G++G  C+ + +  ++            C  GG+CV  D S +CVC +   G  CE+   PC    C +GG CR   G   C C          +   +C  + C++GG C  +   ++C+C   +       N+  C           C + G C    G F C C   GY G +C+  ++
Sbjct:  845 SCDQDINDCDPNPCLNGGSCQD-GVGSFSCSCLPG-FAGPRCARDVDECLSNPCGPGTCTDHVASFTCTCP-PGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLC-RPGYTGAHCQHEADPCLSRPCLHGGVC--SAAHPGFRCTCLES-FTGPQCQTLVDWCSRQPCQNGGRCV--QTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCP-PGYTGLRCEADIN 1207          

HSP 5 Score: 90.1225 bits (222), Expect = 2.337e-16
Identity = 108/394 (27.41%), Postives = 140/394 (35.53%), Query Frame = 1
Query: 2113 CQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCK-NGICQ---IVGNNRI-CNCTGTGFTGFDCEI------------SRC-----------------------------FNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCPL--DFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRC--NKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI----CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKP-KPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSI--INNVFICNCSNVSYTGERCTNKV---GCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            C N GRC  +   + AC C    + GE C ++ P C   PC   G+CQ   + G  R  C C   GF G DC +            +RC                                 C++ G C+   G   C C    Y G LCE P  P     C N G C   Q   L Y      GF G  C  N   CP + C   G C+   ++  C C   +TG  C + +       + C NGG C        CVC   + G+SC +    C    C +G  C        C C      G  C     C    C    IC    +N   IC C    +TG  C   V       N C++ G C   +G F C C   GY G +C+  V+
Sbjct:   49 CANGGRCTQLPSREAACLCPPG-WVGERCQLEDP-CHSGPCAGRGVCQSSVVAGTARFSCRCP-RGFRGPDCSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAG-YTGPLCENPAVPCAPSPCRNGGTC--RQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGK-TGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPP-GFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCG-RGYTGPRCETDVN 433          

HSP 6 Score: 87.8113 bits (216), Expect = 1.165e-15
Identity = 103/377 (27.32%), Postives = 140/377 (37.14%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEF-CDIKRPSCDPNPCKNGICQIVGNNRICNCTGTGFTGFDC--EISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCET--PKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICP------------QNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKP-KPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXX--------XXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVGCPDNYCKNGGACEIHR--------GKFGCNCSLTGYGGEQC 3099
            C  +V +C  N C   G C + +     C C     YG F C+   P C P+ C NG   + G N        G+TG  C  E   C +  C + G+C        C C ++ + G  C+T    C    C N G C    V    YC+C   G+ G  C+    P            +  C   G C+  D S  C C EG TG  CE+ +  C    C +GG C        C C   + G +CE     C    C +GG C  +     C+C     +G  CE  +              C + G C  +   F C C    YTG RC   +    N C++G     H         G F C C   G+ G +C
Sbjct:  884 CARDVDECLSNPC-GPGTCTD-HVASFTCTCPPG--YGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLES-FTGPQCQTLVDWCSRQPCQNGGRC----VQTGAYCLC-PPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGT-LGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPP-GYTGLRCEADI----NECRSGACHAAHTRDCLQDPGGGFRCLCH-AGFSGPRC 1243          

HSP 7 Score: 68.1662 bits (165), Expect = 9.347e-10
Identity = 87/334 (26.05%), Postives = 121/334 (36.23%), Query Frame = 1
Query: 2059 SLFCRACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCET------PKCPLDF---CLNNGHCL----------------------LNQVN-------------QLP----YCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSA-----VCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCE---------KPKPCPVGYCLYGGKCRMVNGMP--RCNCTQ 2847
            SL CR     +    +  CQ  G+C +  ++   C C + +  G  C+ +   C   PC++G  C+      +C C   G+ G +CE  +  C +  CQ+ G CI       C C      G LCE       P  PLD    CL+NG C+                      +N+               Q P     C+C++ GF G RC   +  C    C   G C             C+C + F G +CE+    C + +C  G  C    R P C C     G SC              C    CL+GG CR     P  RC C Q
Sbjct: 1037 SLPCREAAAQIGVRLEQLCQAGGQCVD-EDSSHYCVCPEGR-TGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECL-PGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGTL-GVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHA-GFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQ 1365          

HSP 8 Score: 68.1662 bits (165), Expect = 9.997e-10
Identity = 106/395 (26.84%), Postives = 142/395 (35.95%), Query Frame = 1
Query: 2056 ESLFCRACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGI-----CQIVG------NNRICNCTGTGFTGFDC--EISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCE--TPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCN---------KPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKC--INGGKCVVVDRSPF-CVCAKDFQGKSCEKP-KPCPVGYCLYGGKCRMVNG-----MPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVGCPDNY---------CKNGGACEIHRGK--FGCNCSLTGYGGEQCD 3102
            ES     CQ  V  C +  CQN GRC    +T   C C    + G  CDI+   C     + G+     CQ  G      ++  C C   G TG  C  E+  C    CQ+ G C    G   C+C    Y G  CE    +C    C + G C+      L  C     G  G  C           P+     C  NG C+       C C  G+TG +CE  I  C    C   +   C+      F C+C   F G  C+    PC    C +GG+CR   G        C+C Q  +  +     + C E  C  G  C        C C     +G  C +  G P            C +GG+C        F C C+  G+ G +C+
Sbjct:  990 ESFTGPQCQTLVDWCSRQPCQNGGRCV---QTGAYCLCPPG-WSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCP-EGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPG-YNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSC---PPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGPRCACPP-GLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACA-QGWTGPRCE 1373          
BLAST of notch-1 vs. TrEMBL
Match: A0A0A1CTN9 (Notch-1 (Fragment) OS=Schmidtea mediterranea OX=79327 GN=notch-1 PE=2 SV=1)

HSP 1 Score: 685.256 bits (1767), Expect = 0.000e+0
Identity = 352/352 (100.00%), Postives = 352/352 (100.00%), Query Frame = 1
Query: 2116 QNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGICQIVGNNRICNCTGTGFTGFDCEISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPICSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVDGVMCDYKEPGYAITAFKPP 3171
            QNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGICQIVGNNRICNCTGTGFTGFDCEISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPICSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGKKCEKPKKCPEKYCENGGICSIINNVFICNCSNVSYTGERCTNKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVDGVMCDYKEPGYAITAFKPP
Sbjct:    1 QNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGICQIVGNNRICNCTGTGFTGFDCEISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPICSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGKKCEKPKKCPEKYCENGGICSIINNVFICNCSNVSYTGERCTNKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVDGVMCDYKEPGYAITAFKPP 352          

HSP 2 Score: 85.8853 bits (211), Expect = 1.107e-13
Identity = 79/230 (34.35%), Postives = 115/230 (50.00%), Query Frame = 1
Query: 2095 KCPKNYCQNKGRCYNINETKIA-CDCKKTQFYGEFCDIKRPSCDPNPC-KNGICQIVGNNRICNCTGTGFTGFDCEISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPK-CPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYG-YRCNKPICPQNYCTKNGNCLVRDDSAVCYCDE-GFTGDKCEKPI-CSKDKCINGGKCVVVDRSPFCVCA-KDFQGKSCEK 2763
            KCP ++C N G C      ++  C C  T FYG  C+  +P C  N C KNG C +  ++ +C C   GFTG  CE   C   KC N G C++    P C C K  ++G+ CE PK CP+ +CL  G C +  VN +P C C  T + G        CP+ YC   G C + ++  +C C    +TG++C   + C  + C NGG C +      C C+   + G+ C++
Sbjct:  107 KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCN--KPICPQNYCTKNGNCLVRDDSAVCYCD-EGFTGDKCEKPICSKDKCINGGKCVVVDRSPFCVCAKD-FQGKSCEKPKPCPVGYCLYGGKCRM--VNGMPRCNCTQTNYMGKKCEKPKKCPEKYCENGGICSIINNVFICNCSNVSYTGERCTNKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQ 330          

HSP 3 Score: 63.1586 bits (152), Expect = 2.786e-6
Identity = 64/193 (33.16%), Postives = 95/193 (49.22%), Query Frame = 1
Query: 2098 CPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKN-GICQIVGNNRICNCTGTGFTGFDCEISR-CFNHKCQNNGICILKQGIPECDCTKTVYEG-QLCETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRC-NKPICPQNYCTKNGNCLVRDDSAVCYCD-EGFTGDKCEKPI 2661
            CP+NYC   G C  + +    C C +  F G+ C+  +P C  + C N G C +V  +  C C    F G  CE  + C    C   G C +  G+P C+CT+T Y G +  +  KCP  +C N G C +  +N +  C C++  + G RC NK  CP NYC   G C +      C C   G+ G++C++ +
Sbjct:  147 CPQNYCTKNGNCL-VRDDSAVCYCDEG-FTGDKCE--KPICSKDKCINGGKCVVVDRSPFCVCA-KDFQGKSCEKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGKKCEKPKKCPEKYCENGGICSI--INNVFICNCSNVSYTGERCTNKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKV 332          
BLAST of notch-1 vs. TrEMBL
Match: A0A5K4ELY6 (Cell polarity protein OS=Schistosoma mansoni OX=6183 PE=4 SV=1)

HSP 1 Score: 659.448 bits (1700), Expect = 0.000e+0
Identity = 446/1483 (30.07%), Postives = 719/1483 (48.48%), Query Frame = 1
Query:  127 EVILTSQPIPVSFT-MPDAMLRLHPWNFAKYSSIELEFHTREPRGILFFVGSSTASTDSIGLEIFNSNVYAFGKLLGKDFRIKLNPDNIRVSNGKFFKVAIQILATNYLVLKFDDVEIK-EKIPTPGKLEFNSYTYIGGVDTITRLPWKAFSQTGFTGCINYIRINGERFLDTKQHSKQ-TEM-QGAKTGVCQTSTARCLPGICGPGKCHERSYNMLDQSKNFYCDCSGTFKSYAYSAVDILRGEPCLIDSQRFQCNTKSYLLYTFDKEKT-----THYDDISIDFQTTNT------KEPLFLMKSGTANVINTFLSAEVLAGQVIIIIKXXXXXXXXXXXXXXXXXXXXXDGQWHTLKLSRFAYNVEFYVDEQETISR--------------GELYQSSLEEKFFNKVKEILLGSTTKPPGPDKCTGEIKNFFWNEEDLLGRKNKYGYYSSQLVTEKXXXXXXXXXXXXXXXXCTLKPNHIYTVLNN-IPLTNEGIILFIEFKTKFDGIIWHAVNVFS-SEDWMTLLVNSNSIILAYSLPPNEGVHTIEMTRGGILIQDNTWHRVIINLNKPKEILYIHIDDVESLTNEIKL-KNSKKELAEMNFISLSLGGISDNSQYTQFYNLLRKKNPEVSKLFSGPD--ELKFIGCLGDILVINSSYSGNLIQ--KPNVNSFPKESLFCRACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCK-NGICQIVGNNRICNCTGTGFTGFDCEISRCFNHK-CQNNGICILKQGI---------------------------------------PECDCTKTVYEGQLCETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPICSKDKCINGGKCVV-VDRSPFCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVGCPDNYCKNGGACEIHRGK-FGCNCSLTGYGGEQCDQKVDGVMCDYKEPGYAITAFKPPMVSSGIVTSMGFQTFVKTGTLFCYETADDKYWLIKLVNGRLVADING-ISFNMKTVVSDGRYHFLKVSRDETNFVISLDHFPFENLLIPTAITSILTLPNNIIIYTKLTLCNSCPDTFNRDRFQGAIGSAK-SGHVDISK-GLKXXXXXXXXXXXXXXXXXLTPVMPLPEIPTIQPCYAGFCKNSGKCLVKNYGPRCDCGISGFTGNQCD-QKIMVIKSVPPNPGYVIITRNPVIATNFDLIRFISESSESSTPLTALITPEGNSIEIKIENQKVFVRINGEAKGPLNDKLIEKNVPNFFKLVNLLGRVTVY------------VNGTKLGHIVLKEPLIMKNNSIQISKVLVGANRNADETIKGSLGDFRYNELNLISSNGTFDPNSK 4290
            E   +  P+P++F    D+++R   WNF  Y S E++F T EP GILFFVG      D + +E+F+ NVY    + G    I+LNP    V++G  + V +   A +   +KF++  I  E+     +  F +YTYIG +D + RLPW  +S+  F GCI+ I +N   +LD      Q T++ +G + G C+    RC   ICG G+C  RSY  L++  NF CDCS + K++    +DI R   C  D+   + +    ++Y  D E+      TH DDIS+ F+T  T        PLF      +    ++   +++ GQ+ +   +      +    FF  +S LND +WHTL ++R A  +   VD      +               ++Y  S     F   ++I       PPGP +  GE +NF+WN+ DL+G K     Y++ L+         P +PRQ     T K   IY  +N  I + N G    IEFKT +DGI++ A ++ + S   +T ++ S  I + YS+   +GV+ I    G   + D  WHR+ I L K  + +  ++D     +NE  + KN + +L  ++   +  GGI ++ ++    NLLR+ + +  +     D  +    GC+G   +  ++++ NL++     + ++P   L    C + +K+C  +YC + G C  I+++++ C C  T   G  C      C P  CK NG C+IV    +C+C+ TG+TG  CEIS C +   C NNG C +   +                                       P C+C  T Y G  CET  CP+++C N G C +   ++ P C C+ T + G  CN P+CP NYCT +G C+VR  +  C C  G+ G +CE  +C  + C+NGG C    D  P C C  +F+G+ CE  K CP  YCL+GG+C M  G+P+C+C  T+Y G +CE P+ CP  YC+N G+CS+ +  ++C+C+   Y G  CT  + CP NYC NGG C +  G  + C+CS+T   G QCD    G+   Y+  GY I    P + +     + GF+T++ +GTL  + T D KYW IKL +GR++ D  G I+ +     +DG YH + + R     +++ D       ++  ++  ++   +N +IY  + L     D    D F+G IG    +G   I     +   + G   ++      + P  P PE      C + +C N G+C  +NY  +CDC  + + G +C+ Q    +  +P N  YVI    P+  TN D +R   ++  +  P+  ++  +G+  E+ + N K++  ING          +E  + N  ++ N  GR+ V             ++G    H V    ++  + S+   ++++GA+R    T KG +G F +N   LI+  G+   N+K
Sbjct:  599 ESEFSRTPVPITFMGTDDSIVRFDTWNFELYRSFEIKFSTYEPNGILFFVGPDQEHRDFVCVELFDGNVYFVYAVGGHYKHIRLNPPKTVVNDGGIYSVYVSRNAQHRFTVKFNNQLIDVEEGKEAHQAAFATYTYIGSIDNVGRLPWHVWSRENFAGCIHSILVNENSYLDVSSRMIQHTDIGKGIRLGQCEVPKQRCNEKICGGGRCSRRSYPFLEE-LNFACDCSESDKTFPEKTMDIRRSVGCDRDAPILEMDGD--MVYVIDFEEQINKLITHTDDISLQFKTETTLYGQSDHLPLFY---SVSRADKSYFRVDLVNGQIRVQTNINHKGKSHEYEEFFLPSSTLNDNRWHTLHIARRADYIVISVDRASITGKIPLLDPHDTFQLIAQQIYLGSAGPPNFGYYQDIDTKKIMLPPGP-RFIGEFRNFYWNQYDLIGTKLFPTKYTTHLLNPPSIRHKFPIWPRQQTYAITCKSGLIYAHMNKPITMKNGGDTWLIEFKTNYDGILFRARDINNPSGIHITAMILSGRIHIIYSIHDQQGVYQITSGPGADNVADGNWHRLAITLRKYNKEILAYLD---GYSNEYLVGKNLRVDL--LSQFDIFFGGIPEH-EWLTLLNLLRRYSIQSLERSEAKDGQQPSLTGCIGSFNIRANNFTDNLLKLYDSYLTAYPANELIRGYCMD-LKRCTPSYCHHGGTCRQISDSEVQCICTGTGHEGPRCANPITECPPGYCKNNGRCKIVNGQPVCDCSSTGYTGTMCEISPCSSGTYCHNNGRCYMMGSVAACDCKGTGFTGPRCLESICTPGYCGYGGVCTVDPRTQQPVCNCRGTGYTGARCETRICPVNYCENYGECKVGPDDR-PTCDCSRTNYAGPTCNIPLCPPNYCTGHGICVVRQRNPTCDCYPGYRGPRCEIEVCPSNYCMNGGTCYPGPDHRPHCTCPVNFEGEQCEMRKLCPPDYCLHGGRCTMNRGIPKCDCLGTDYKGTQCEIPETCPIGYCQNNGVCSVKSGSYVCDCTGTGYRGRTCTEPITCPPNYCNNGGICSVLPGNVYRCDCSMTARTGPQCDSSAHGIHIGYERDGYLIYNLIPSIRTIDDNVTFGFKTYMNSGTLVTFLTTDGKYWAIKLRDGRVIVDTGGKITHDFGMRSNDGNYHIINIERKGRTMIVTQD-----GEVLRLSLQDLVNPYDNSLIYNAIHL---AVDEKKSDIFRGVIGGLHWNGRYPIDDLNARIVTSTGTVTIVPTPGFQIHPPRPQPE------CISDYCSNGGRCYAENYQRKCDCRYTAYNGARCERQSRGFMPQLPDNGAYVIYQIQPLNRTNRDQLRVAFQTWYNDGPIVRVVQTDGSYYEVYLRNGKLYTNING----------VEFTLSNPSQIFN-DGRMHVITMDRNKSQFNYTIDGHHTSHYV--PSIVSVDGSLISQEIILGADRTYQNTFKGVIGAFYWNGQYLINQIGSLASNTK 2039          

HSP 2 Score: 259.225 bits (661), Expect = 3.096e-65
Identity = 164/463 (35.42%), Postives = 250/463 (54.00%), Query Frame = 1
Query: 4657 LLQEKASIQLISGGFQADTNETMIHTMR-QNRMDMNKTSDFFTSNGFNK-----STFGTTGSADFEKIQPVKYASIFAQQDTDLQQPNVFSEEEMKIDCCVMSNNSRYAITGSVAGPPQVWDLNDGFLTHIMDGANQACTSLHLAMNNSVLI--------GLVTQNQ-QPFSLKLLMMWKFPDGQIIDSGYEYMCTTCCVSADGECVILADDMKDS-SITILNLTNQQTRKLV--YKAGLVNGDGIQLLKQTKNGQFLIAGFQTFDNSTSY-MVFDMTMQS---RKNGVFKINANTNCTDFINNNEAVTGTESGELIIWDLNTVQAVRRILISPNFVD-NSESRNPHKDSLTCVTVSNDGSLLATTGLDATVKVWNMEDEKLLYNLNKHKDEIQSLVWSNDNEMLVSGSLDGSIRIWNVTNGQEMCGFNSNIEITXXXXXXXXXXXXGLGERAGVNKLVMLKI 5976
            LL +  +I ++ G        T + +++ Q+R+     S      G N         G +G +     QPV         D   +Q NV++ E MK+DC V++ NS+Y +TGS  GPPQVWD   G L  IMDG    CT LHLA ++SVL+        GL T N+     +K L +W F  G+ ++   E MCT  C++   E VI+A   ++  +I + NLT  Q+  ++  +    +  D +  L  + + + ++AG     +  +Y MVFD+T       +      NA    T+ I N+EAVTGT  GEL +W+L T + +R+I IS      N     PH +++ CV +S DG  L T   D T ++W M DE+LL+ L  H D++ S+  S D+E++V+GS DGSIR+W + +G +MC F SNIEI +V +S+DK+ +V LGER+G  KL+ML++
Sbjct: 2212 LLSDNGNIGIVDGAATGGMTATSLQSLQTQSRIVKAPLSVTSYPIGHNHRLDLTDQIGASGISTIRIDQPV-------MDDLSARQ-NVYNMEGMKVDCVVITKNSKYVVTGSGMGPPQVWDTQSGDLCKIMDGQEFGCTDLHLACDDSVLVAQVLDDITGLDTLNEPSEIRVKRLQLWDFATGRQLEMPIEIMCTATCITRSSEYVIIAQVTQEGPAILVWNLTGNQSDHIIPYHPVNPLLKDSVSYLNISLDDRLVVAGLNNPTDELAYFMVFDLTASYVGIHQPKFITFNAKAEATEIIGNDEAVTGTRRGELFVWNLLTGRVMRQIQISATLEGGNLTMLPPHTETIHCVKLSTDGHYLVTGSQDQTARIWTMPDERLLHTLEGHADDVLSVAISLDSEVVVTGSWDGSIRVWRIRDGNQMCWFTSNIEILQVKISNDKRALVALGERSGHRKLIMLQV 2666          
BLAST of notch-1 vs. TrEMBL
Match: A0A3Q0KLP9 (Cell polarity protein OS=Schistosoma mansoni OX=6183 PE=4 SV=1)

HSP 1 Score: 657.136 bits (1694), Expect = 0.000e+0
Identity = 446/1483 (30.07%), Postives = 719/1483 (48.48%), Query Frame = 1
Query:  127 EVILTSQPIPVSFT-MPDAMLRLHPWNFAKYSSIELEFHTREPRGILFFVGSSTASTDSIGLEIFNSNVYAFGKLLGKDFRIKLNPDNIRVSNGKFFKVAIQILATNYLVLKFDDVEIK-EKIPTPGKLEFNSYTYIGGVDTITRLPWKAFSQTGFTGCINYIRINGERFLDTKQHSKQ-TEM-QGAKTGVCQTSTARCLPGICGPGKCHERSYNMLDQSKNFYCDCSGTFKSYAYSAVDILRGEPCLIDSQRFQCNTKSYLLYTFDKEK-----TTHYDDISIDFQTTNT------KEPLFLMKSGTANVINTFLSAEVLAGQVIIIIKXXXXXXXXXXXXXXXXXXXXXDGQWHTLKLSRFAYNVEFYVDEQETISR--------------GELYQSSLEEKFFNKVKEILLGSTTKPPGPDKCTGEIKNFFWNEEDLLGRKNKYGYYSSQLVTEKXXXXXXXXXXXXXXXXCTLKPNHIYTVLNN-IPLTNEGIILFIEFKTKFDGIIWHAVNVFS-SEDWMTLLVNSNSIILAYSLPPNEGVHTIEMTRGGILIQDNTWHRVIINLNKPKEILYIHIDDVESLTNEIKL-KNSKKELAEMNFISLSLGGISDNSQYTQFYNLLRKKNPEVSKLFSGPD--ELKFIGCLGDILVINSSYSGNLIQ--KPNVNSFPKESLFCRACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCK-NGICQIVGNNRICNCTGTGFTGFDCEISRCFNHK-CQNNGICILKQGI---------------------------------------PECDCTKTVYEGQLCETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPICSKDKCINGGKCVV-VDRSPFCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVGCPDNYCKNGGACEIHRGK-FGCNCSLTGYGGEQCDQKVDGVMCDYKEPGYAITAFKPPMVSSGIVTSMGFQTFVKTGTLFCYETADDKYWLIKLVNGRLVADING-ISFNMKTVVSDGRYHFLKVSRDETNFVISLDHFPFENLLIPTAITSILTLPNNIIIYTKLTLCNSCPDTFNRDRFQGAIGSAK-SGHVDISK-GLKXXXXXXXXXXXXXXXXXLTPVMPLPEIPTIQPCYAGFCKNSGKCLVKNYGPRCDCGISGFTGNQCD-QKIMVIKSVPPNPGYVIITRNPVIATNFDLIRFISESSESSTPLTALITPEGNSIEIKIENQKVFVRINGEAKGPLNDKLIEKNVPNFFKLVNLLGRVTVY------------VNGTKLGHIVLKEPLIMKNNSIQISKVLVGANRNADETIKGSLGDFRYNELNLISSNGTFDPNSK 4290
            E   +  P+P++F    D+++R   WNF  Y S E++F T EP GILFFVG      D + +E+F+ NVY    + G    I+LNP    V++G  + V +   A +   +KF++  I  E+     +  F +YTYIG +D + RLPW  +S+  F GCI+ I +N   +LD      Q T++ +G + G C+    RC   ICG G+C  RSY  L++  NF CDCS + K++    +DI R   C  D+   + +    ++Y  D E+      TH DDIS+ F+T  T        PLF      +    ++   +++ GQ+ +   +      +    FF  +S LND +WHTL ++R A  +   VD      +               ++Y  S     F   ++I       PPGP +  GE +NF+WN+ DL+G K     Y++ L+         P +PRQ     T K   IY  +N  I + N G    IEFKT +DGI++ A ++ + S   +T ++ S  I + YS+   +GV+ I    G   + D  WHR+ I L K  + +  ++D     +NE  + KN + +L  ++   +  GGI ++ ++    NLLR+ + +  +     D  +    GC+G   +  ++++ NL++     + ++P   L    C + +K+C  +YC + G C  I+++++ C C  T   G  C      C P  CK NG C+IV    +C+C+ TG+TG  CEIS C +   C NNG C +   +                                       P C+C  T Y G  CET  CP+++C N G C +   ++ P C C+ T + G  CN P+CP NYCT +G C+VR  +  C C  G+ G +CE  +C  + C+NGG C    D  P C C  +F+G+ CE  K CP  YCL+GG+C M  G+P+C+C  T+Y G +CE P+ CP  YC+N G+CS+ +  ++C+C+   Y G  CT  + CP NYC NGG C +  G  + C+CS+T   G QCD    G+   Y+  GY I    P + +     + GF+T++ +GTL  + T D KYW IKL +GR++ D  G I+ +     +DG YH + + R     +++ D       ++  ++  ++   +N +IY  + L     D    D F+G IG    +G   I     +   + G   ++      + P  P PE      C + +C N G+C  +NY  +CDC  + + G +C+ Q    +  +P N  YVI    P+  TN D +R   ++  +  P+  ++  +G+  E+ + N K++  ING          +E  + N  ++ N  GR+ V             ++G    H V    ++  + S+   ++++GA+R    T KG +G F +N   LI+  G+   N+K
Sbjct:  542 ESEFSRTPVPITFMGTDDSIVRFDTWNFELYRSFEIKFSTYEPNGILFFVGPDQEHRDFVCVELFDGNVYFVYAVGGHYKHIRLNPPKTVVNDGGIYSVYVSRNAQHRFTVKFNNQLIDVEEGKEAHQAAFATYTYIGSIDNVGRLPWHVWSRENFAGCIHSILVNENSYLDVSSRMIQHTDIGKGIRLGQCEVPKQRCNEKICGGGRCSRRSYPFLEE-LNFACDCSESDKTFPEKTMDIRRSVGCDRDAPILEMDGD--MVYVIDFEEQINKLITHTDDISLQFKTETTLYGQSDHLPLFY---SVSRADKSYFRVDLVNGQIRVQTNINHKGKSHEYEEFFLPSSTLNDNRWHTLHIARRADYIVISVDRASITGKIPLLDPHDTFQLIAQQIYLGSAGPPNFGYYQDIDTKKIMLPPGP-RFIGEFRNFYWNQYDLIGTKLFPTKYTTHLLNPPSIRHKFPIWPRQQTYAITCKSGLIYAHMNKPITMKNGGDTWLIEFKTNYDGILFRARDINNPSGIHITAMILSGRIHIIYSIHDQQGVYQITSGPGADNVADGNWHRLAITLRKYNKEILAYLD---GYSNEYLVGKNLRVDL--LSQFDIFFGGIPEH-EWLTLLNLLRRYSIQSLERSEAKDGQQPSLTGCIGSFNIRANNFTDNLLKLYDSYLTAYPANELIRGYCMD-LKRCTPSYCHHGGTCRQISDSEVQCICTGTGHEGPRCANPITECPPGYCKNNGRCKIVNGQPVCDCSSTGYTGTMCEISPCSSGTYCHNNGRCYMMGSVAACDCKGTGFTGPRCLESICTPGYCGYGGVCTVDPRTQQPVCNCRGTGYTGARCETRICPVNYCENYGECKVGPDDR-PTCDCSRTNYAGPTCNIPLCPPNYCTGHGICVVRQRNPTCDCYPGYRGPRCEIEVCPSNYCMNGGTCYPGPDHRPHCTCPVNFEGEQCEMRKLCPPDYCLHGGRCTMNRGIPKCDCLGTDYKGTQCEIPETCPIGYCQNNGVCSVKSGSYVCDCTGTGYRGRTCTEPITCPPNYCNNGGICSVLPGNVYRCDCSMTARTGPQCDSSAHGIHIGYERDGYLIYNLIPSIRTIDDNVTFGFKTYMNSGTLVTFLTTDGKYWAIKLRDGRVIVDTGGKITHDFGMRSNDGNYHIINIERKGRTMIVTQD-----GEVLRLSLQDLVNPYDNSLIYNAIHL---AVDEKKSDIFRGVIGGLHWNGRYPIDDLNARIVTSTGTVTIVPTPGFQIHPPRPQPE------CISDYCSNGGRCYAENYQRKCDCRYTAYNGARCERQSRGFMPQLPDNGAYVIYQIQPLNRTNRDQLRVAFQTWYNDGPIVRVVQTDGSYYEVYLRNGKLYTNING----------VEFTLSNPSQIFN-DGRMHVITMDRNKSQFNYTIDGHHTSHYV--PSIVSVDGSLISQEIILGADRTYQNTFKGVIGAFYWNGQYLINQIGSLASNTK 1982          

HSP 2 Score: 259.225 bits (661), Expect = 2.636e-65
Identity = 164/463 (35.42%), Postives = 250/463 (54.00%), Query Frame = 1
Query: 4657 LLQEKASIQLISGGFQADTNETMIHTMR-QNRMDMNKTSDFFTSNGFNK-----STFGTTGSADFEKIQPVKYASIFAQQDTDLQQPNVFSEEEMKIDCCVMSNNSRYAITGSVAGPPQVWDLNDGFLTHIMDGANQACTSLHLAMNNSVLI--------GLVTQNQ-QPFSLKLLMMWKFPDGQIIDSGYEYMCTTCCVSADGECVILADDMKDS-SITILNLTNQQTRKLV--YKAGLVNGDGIQLLKQTKNGQFLIAGFQTFDNSTSY-MVFDMTMQS---RKNGVFKINANTNCTDFINNNEAVTGTESGELIIWDLNTVQAVRRILISPNFVD-NSESRNPHKDSLTCVTVSNDGSLLATTGLDATVKVWNMEDEKLLYNLNKHKDEIQSLVWSNDNEMLVSGSLDGSIRIWNVTNGQEMCGFNSNIEITXXXXXXXXXXXXGLGERAGVNKLVMLKI 5976
            LL +  +I ++ G        T + +++ Q+R+     S      G N         G +G +     QPV         D   +Q NV++ E MK+DC V++ NS+Y +TGS  GPPQVWD   G L  IMDG    CT LHLA ++SVL+        GL T N+     +K L +W F  G+ ++   E MCT  C++   E VI+A   ++  +I + NLT  Q+  ++  +    +  D +  L  + + + ++AG     +  +Y MVFD+T       +      NA    T+ I N+EAVTGT  GEL +W+L T + +R+I IS      N     PH +++ CV +S DG  L T   D T ++W M DE+LL+ L  H D++ S+  S D+E++V+GS DGSIR+W + +G +MC F SNIEI +V +S+DK+ +V LGER+G  KL+ML++
Sbjct: 2155 LLSDNGNIGIVDGAATGGMTATSLQSLQTQSRIVKAPLSVTSYPIGHNHRLDLTDQIGASGISTIRIDQPV-------MDDLSARQ-NVYNMEGMKVDCVVITKNSKYVVTGSGMGPPQVWDTQSGDLCKIMDGQEFGCTDLHLACDDSVLVAQVLDDITGLDTLNEPSEIRVKRLQLWDFATGRQLEMPIEIMCTATCITRSSEYVIIAQVTQEGPAILVWNLTGNQSDHIIPYHPVNPLLKDSVSYLNISLDDRLVVAGLNNPTDELAYFMVFDLTASYVGIHQPKFITFNAKAEATEIIGNDEAVTGTRRGELFVWNLLTGRVMRQIQISATLEGGNLTMLPPHTETIHCVKLSTDGHYLVTGSQDQTARIWTMPDERLLHTLEGHADDVLSVAISLDSEVVVTGSWDGSIRVWRIRDGNQMCWFTSNIEILQVKISNDKRALVALGERSGHRKLIMLQV 2609          
BLAST of notch-1 vs. TrEMBL
Match: A0A068XZS4 (Neurogenic locus notch protein OS=Echinococcus multilocularis OX=6211 GN=EmuJ_000343000 PE=4 SV=1)

HSP 1 Score: 646.736 bits (1667), Expect = 0.000e+0
Identity = 448/1360 (32.94%), Postives = 689/1360 (50.66%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCEISRCFNHKCQNNGICILKQG--IPECDCTKTVYEGQLCETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPICSKDKCINGGKCVV-VDRSPFCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVDGVMCDYKEPGYAITAFKPPMVSSGIVTSMGFQTFVKTGTLFCYETADDKYWLIKLVNGRLVADINGISFNMKTVVSDGRYHFLKVSRDETNFVISLDHFPFENLLIPTAITSILTLPNNIIIYTKLTLCNSCPDTFNRDRFQGAIGSA---KSGHVDISKGLKXXXXXXXXXXXXXXXXXLTPVMPLPEIPTIQPCYAGFCKNSGKCLVKNYGPRCDCGISGFTGNQCDQKIM-VIKSVPPNPGYVIITRNPVIATNFDLIRFISESSESSTPLTALITPEGNSIEIKIENQKVFVRINGEAKGPLNDKLIEKNVPNFFKLVNLL---GRVTVYVNGTKLGHIVLKEPLIMKNNSIQISKVLVGANRNADETIKGSLGDFRYNELNLISSNGTFDPNSKQIPNIKLEQWKMIGRK-------MPDINK-----------------VRKGSHGGVVF----TSTKFIIADGFGAGDV-VSISNGPIVLGAQLLGAKTIG-VDPFXXXXXXXXXXXXXXXXWAFMNLIFS--RTHVTASGNKLLLIENNDLQISPLLQEKASIQLISGGFQADTNETMIHTMRQNRMDMNKTSDFFTSNGFNKS--TFGTTGSADFEKIQPVKYASIFAQQDTDLQQPNVFSEEEMKIDCCVMSNNSRYAITGSVAGPPQVWDLNDGFLTHIMDGANQACTSLHLAMNNSVLIGLVTQN-QQPFSLKL--LMMWKFPDGQIIDSGYEYMCTTCCVSADGECVILADDM-KDSSITILNLT-NQQTRKLVYKAGLVNGDG-IQLLKQTKNGQFLIAGFQT-FDNSTSYMVFDMTMQSR---KNGVFKINANTNCTDFINNNEAVTGTESGELIIWDLNTVQAVRRILISPNFVDNSESR--NPHKDSLTCVTVSNDGSLLATTGLDATVKVWNMEDEKLLYNLNKHKDEIQSLVWSNDNEMLVSGSLDGSIRIWNVTNGQEMCGFNSNIEITXXXXXXXXXXXXGLGERAGVNKLVMLKILRN 5985
            C++++  CP  +C N GRC  +   +  CDC  T + G+ C    P C PN C NG +C +   N  CNCTG  F G  C    C    C NNG C ++ G   PECDCT T +    C +P CP  +CLN G C     N+LP+C C+ T F G +C  PIC  +YC+ +G C V     VC C   + G +C+  +C    C + G C    DR P C C + ++G  CE PK CP GYC +GG+C M +GMP CNC  T+Y G +CE PK CP  YC+NGG+C +    + CNC    + G  C++ + CP  YC  G    +  G++ CNC  TG  G  CD  V+G+  DY+E GY +    PP+ +     ++GF+T+ ++GT+  + T    +W IK+ NG +V D NG  +    VV+DG YH + V R     +++ D+    NL     +T I+   +  I YT L +     +    D F GAIG         +D +KG       G  I  G +  +L P   LP    +  C A +C N G C V++Y  +CDC ++G+ G++C++    V+ S   N  Y+II   P   TN D +R   ++     P+   +  +G   EI ++ Q+VFV  N + +  L     ++       ++ L+    R    V+G ++  + + + L+  N ++  +++++GA+R    T  G LG F +N   L++ NG   P S    N+ +   + +G+K       MP   +                    G HGG +       + F+ + G+G G   V   +GP++L  Q  GA   G ++P++ GI++  + LI ALIWA            +  +G K   + +      PLL    S+   +G F         H +          + FFT+ G +KS   FG     D       +Y      Q  +   PNV++ +++K+DCCV++ NSRY +TGS  GPPQVWD+  G    +M+G    C  LHLA+ +++L+G V ++ Q   S K+  L +W F  G+ ++   E +C+  CVS  GE ++ A    +  SI + +L  NQ TR++ Y   L+N +  +  +  T   + ++AGF     +   +MVFD+  ++R   +       A    T+ +NN EAVTGT  GELI+W+L T   VR+I I+     +S      PH+  +  + +S D   L T   D  ++VW M +E+LL+ L  H D++ S+V S D+EM+VSGS DGSIR+W + +G +MC F SNIE+ +V LS DK+ +VGLGER G  KL+M++I+R+
Sbjct: 1719 CEQSI--CPDGFCLNGGRC-TVQNGRPVCDCSGTDYRGDRC--SHPICPPNFCLNGGVCYVYDGNPRCNCTGN-FGGDRCHYPVCPPGYCLNNGRCFIRPGSSAPECDCTDTGFTDDRCSSPVCPEGYCLNGGVCRA-LPNRLPFCDCSYTSFTGDKCEVPICSPDYCSGHGTCRVEQGRPVCECHLEYWGPQCQLEVCPPGFCHHSGTCYPGPDRRPHCRCPEGYEGDQCEMPKTCPPGYCYHGGECTMQSGMPVCNCINTDYQGPRCETPKTCPPGYCQNGGLCMVSGGRYTCNCLATGFQGPTCSDPIACPPGYCHGGICTVLPGGRYVCNCWKTGLSGPTCDGDVNGIYIDYEEIGYMVYDLNPPLKTKVDNVTVGFKTYAQSGTILDFVTTTGSHWGIKVRNGHIVIDRNGQEYMYPNVVNDGAYHVVSVERKGDRMLVTFDNDQIVNL----PMTGIIERSDQSITYTTLYVGA---NKNKEDIFHGAIGGLYWNGRYPIDEAKG-------GLQIATGDVIYVLLPSFILPGKKPVPVCPADYCFNGGVCYVEDYELKCDCRLTGWQGSRCEKPTHGVLPSTSGNGAYIIIRVVPPKPTNLDRMRVAFQTYAIDGPIARFMLSDGRFYEIYMKGQQVFVS-NSKDEIRLISAPYQQCDDGKMHVITLVRNGSRFDWSVDGHRI--VYVDKSLVDSNGALITNELILGADRKFTHTFNGVLGAFDWNGQLLVNDNGELSPES----NVMIVPGRGVGKKEDVVIVVMPHFMQPPLATTAAPPLPFPPLIPPDGIHGGAIVGGAGEGSLFVPSMGYGGGASGVFAGSGPLLL--QAGGAGFFGLINPWLAGILVCLLPLISALIWACWRCKPGCCPCCIGGAGGKTAGVSSK-----PLLATNGSVSQ-TGNF---------HPVPPG------GASFFTTGGQSKSGYVFGQDRQVDITD----RYDMTMLDQHME-GVPNVYTTDDLKVDCCVLTQNSRYVVTGSANGPPQVWDMQTGEPFKVMNGDELGCNDLHLAVQDTLLVGQVIEDFQSADSTKMHRLQLWNFVTGEQLEMPAEILCSASCVSNAGEHIVAARATPQGQSILVWDLRGNQLTREIPY--ALINPNARVSYINITPEDRLIVAGFNNPGTDQACFMVFDLAAEARGVVQPKYITFEAKVEATEILNNEEAVTGTRKGELIVWNLLTTTPVRQITINATLEGDSAMTVFPPHEGIIHDIVLSEDRRFLVTASQDRRIRVWTMPEERLLHTLEGHADDVLSVVVSCDSEMVVSGSWDGSIRVWRMKDGSQMCIFTSNIEVLQVKLSRDKRAIVGLGERNGHRKLIMMQIVRS 3020          

HSP 2 Score: 505.368 bits (1300), Expect = 9.213e-142
Identity = 333/1025 (32.49%), Postives = 527/1025 (51.41%), Query Frame = 1
Query:  130 VILTSQPIPVSFT-MPDAMLRLHPWNFAKYSSIELEFHTREPRGILFFVGSSTASTDSIGLEIFNSNVYAFGKLLGKDFR-IKLNPDNIRVSNGKFFKVAIQILATNYLVLKFDDVEIK-EKIPTPGKLEFNSYTYIGGVDTITRLPWKAFSQTGFTGCINYIRINGERFLD-TKQHSKQTEM-QGAKTGVCQTSTARCLPGICGPGKCHERSYNMLDQSKNFYCDCSGTFKSYAYSAVDILRGEPCLIDSQRFQCNTKSYLLYTFDKEK---TTHYDDISIDFQTTNTKEPLFLMKSGTANVINTFLSAEVLAGQVIIIIKXXXXXXXXXXXXXXXXXXXXXDGQWHTLKLSRFAYNVEFYVDEQETISRGELYQSSLEEKFFNKVKEILLGS------TTKP--------PGPDKCTGEIKNFFWNEEDLLGRKNKYGYYSSQLVTEKXXXXX--XXXXXXXXXXXCTLKPNHIYTVLNNIPLTNEGIILFIEFKTKFDGIIWHAVNVFSSEDWMTLLVNSNSIILAYSLPPNEGVHTIEMTRGGILIQDNTWHRVIINLNKPKEILYIHIDDVESLTNEIKLKNSKKELAEMNFISLSLGGISDNSQYTQFYNLLRKKNPEVSKLFSGPD--ELKFIGCLGDILVINSSYSGNLIQK--PNVNSFPKESLFCRACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKN-GICQIVGNNRICNCTGTGFTGFDCEISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICPQNYCTKNGNCLVRDDSAVCYCD-EGFTGDKCEKPICSKDKCINGGKCVVVDRSPFCVC-AKDFQGKSCEKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKV 3111
            + L + P+PV+F     +++R   W+F+ + S E+EF T EP G+LFFVG     TD + +E+F+ NVY F   +G  +R I+LNP + +V+ G   +V ++    +  ++K++  EI  ++  +  + EF+SYTY G +D  +R PW  +S+  F GCIN+IR+N ++FLD   + ++ T++ +G + GVC+    RC   ICG G+CHE+SY    +  NF CDCS + K++     DI R E C  D+     + ++ ++  F+++    TTH DDI++ F+T +   PLF+  S TA     +   E+  G + +   + +++     + F  ++  LND  WHTL++ R A  +   VD     + G L     +  F N  ++I +G        + P        P   K  GE++NF+WN+ D  G +    +Y++ ++T +  LP     P      + CT K N   T+   +     G +  +EFKTK+DG++ HA +  +   + TL++    + L YS+    GVH  E+    I + +N WHRV   L++ K    I +DD    T   +L+++      +N ++ S GG+     +++   ++R   P  + L SG +       GCLG        +  +L++K    + S+P   +    C++ V +C  +YC + G C  ++ET + CDC  T + G  C+ +  +C  N C N GIC IVG N +CNC GTG+ G  CE   C    C N GIC +  G P C+C  T ++G  C+   C  ++C N G C +   N  P C C+ TG+ G  C +PIC   YC+  G C ++  S +C C    + G  CE PIC    C NGG+CVV +  P C C    + G  C++P  C   YC  GG+C + NG P C+C  T Y G        CP  YC+NGG C + N   +C+C    Y G RC   + CP NYC NGG C +  G+  C+C+ T Y G  C+  +
Sbjct:  576 ITLHTSPMPVTFMGTQSSVVRFDTWDFSVFHSFEIEFRTFEPNGVLFFVGPDREHTDFVCVELFDGNVY-FAYGIGDHYRHIQLNPTSRKVNTGTAHRVYVERTPQHRFIVKYNGQEIDVDQGTSRHQAEFSSYTYFGSIDQPSRFPWIVWSRENFAGCINFIRVNDDKFLDPASRMNQHTDLSRGIQFGVCKAPDLRCNREICGGGQCHEQSYPFF-EPMNFACDCSASDKTFREGVEDIRRSEACNRDAPIVDFDGETVIMIDFERQMNTLTTHTDDINLQFKTNSLYAPLFVAVS-TAE--KQYFRVELENGLIKVSTNMNKASKPPRDAEFLLQSPRLNDNNWHTLRIRRRAQFLYISVDNASE-NNGVLVVEIPKGVFNNIAQQIYVGGPMPENYASPPYGNMAGFLPKGSKFVGEMRNFYWNQYDFFGTRQLPTHYTTDVLTPRLELPTFPSWPREPMYSITCTSKLN-WGTIQVPMKAKEVGDMWLLEFKTKYDGVLAHARDENTGSHF-TLMILKGRLHLIYSIGGVTGVH--EIINSPISVANNRWHRVTFGLDRVKGRFVIIVDDSAPETFGHRLQHNT-----LNSLTFSFGGVP--GIWSKILEIIRLHAP--TSLPSGYEGSPPALTGCLGGFSTRTDRFLVDLLKKYDTQLESYPTGEIIRGYCRDLV-RCTPDYCLHGGVCTKMSETLLHCDCTNTGYTGLHCEDRVTTCPRNYCLNGGICTIVGTNPVCNCQGTGYYGDRCESPVCSPDYCMNGGICSVVNGQPLCNCRNTGFDGARCDAIICRPNYCRNGGICSIQ--NGRPVCSCSGTGYDGPLCEQPICRPGYCSNGGICRIQGGSPICDCSGTDYDGKYCENPICRPGYCQNGGRCVVENGLPVCECRGTGYGGSRCDQPI-CTPSYCQNGGRCILENGRPVCDCRGTGY-GGSRCDRVICPPDYCQNGGRCVVENGRPLCDCRGTEYGGSRCDQAI-CPPNYCLNGGRCIVRGGQPVCDCTSTRYQGRVCEVPI 1575          

HSP 3 Score: 241.506 bits (615), Expect = 7.872e-60
Identity = 136/341 (39.88%), Postives = 180/341 (52.79%), Query Frame = 1
Query: 2098 CPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGICQIVGNN-RICNCTGTGFTGFDCEISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICPQNYCTKNGNCLVRDDSAVCYCDEG-FTGDKCEKPICSKDKCINGGKCVVVDRSPFCVC-AKDFQGKSCEKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKV 3111
            C   YC N G C  I      CDC  T + G++C+   P C P  C+NG   +V N   +C C GTG+ G  C+   C    CQN G CIL+ G P CDC  T Y G  C+   CP D+C N G C++   N  P C C  T + G RC++ ICP NYC   G C+VR    VC C    + G  CE PIC  D C++GG+C+V      C C   + +G +CE P  C  GYC+ GG C +VNG P C+C+ T Y G +  +   C   +C N G C + N   IC+C +  + G+ C   +  PD YC NGG C +  G+  C+C  TGYGG  C+Q +
Sbjct: 1391 CRPGYCSNGGIC-RIQGGSPICDCSGTDYDGKYCE--NPICRPGYCQNGGRCVVENGLPVCECRGTGYGGSRCDQPICTPSYCQNGGRCILENGRPVCDCRGTGYGGSRCDRVICPPDYCQNGGRCVVE--NGRPLCDCRGTEYGGSRCDQAICPPNYCLNGGRCIVRGGQPVCDCTSTRYQGRVCEVPICRPDFCLHGGQCIVQGDRAVCDCRGTNHEGINCETPI-CQPGYCMNGGICTIVNGRPACDCSNTGY-GGQLCEQPICRPGFCLNSGRCIVQNGQAICDCRDTGFVGQHCEQSICRPD-YCMNGGICSVINGQPVCDCRDTGYGGPLCEQSI 1723          

HSP 4 Score: 238.81 bits (608), Expect = 5.717e-59
Identity = 136/344 (39.53%), Postives = 184/344 (53.49%), Query Frame = 1
Query: 2098 CPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPC-KNGICQIVGNNRICNCTGTGFTGFDCEISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICPQNYCTKNGNCLVRDDSAVCYC-DEGFTGDKCEKPICSKDKCINGGKCVVVDRSPFCVCA-KDFQGKSCEKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSII--NNVFICNCSNVSYTGERCTNKVGCPDNYCKNGGACEIHRGKFG-CNCSLTGYGGEQCDQKV 3111
            CP NYC N GRC  +   +  CDC  T++ G  C++  P C P+ C   G C + G+  +C+C GT   G +CE   C    C N GIC +  G P CDC+ T Y GQLCE P C   FCLN+G C++   N    C C  TGF G  C + IC  +YC   G C V +   VC C D G+ G  CE+ IC    C+NGG+C V +  P C C+  D++G  C  P  CP  +CL GG C + +G PRCNCT     G        CP  YC N G C I   ++   C+C++  +T +RC++ V CP+ YC NGG C     +   C+CS T + G++C+  +
Sbjct: 1539 CPPNYCLNGGRCI-VRGGQPVCDCTSTRYQGRVCEV--PICRPDFCLHGGQCIVQGDRAVCDCRGTNHEGINCETPICQPGYCMNGGICTIVNGRPACDCSNTGYGGQLCEQPICRPGFCLNSGRCIVQ--NGQAICDCRDTGFVGQHCEQSICRPDYCMNGGICSVINGQPVCDCRDTGYGGPLCEQSICPDGFCLNGGRCTVQNGRPVCDCSGTDYRGDRCSHPI-CPPNFCLNGGVCYVYDGNPRCNCTGN--FGGDRCHYPVCPPGYCLNNGRCFIRPGSSAPECDCTDTGFTDDRCSSPV-CPEGYCLNGGVCRALPNRLPFCDCSYTSFTGDKCEVPI 1873          
BLAST of notch-1 vs. TrEMBL
Match: A0A5K3EZB5 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1)

HSP 1 Score: 642.114 bits (1655), Expect = 0.000e+0
Identity = 457/1374 (33.26%), Postives = 678/1374 (49.34%), Query Frame = 1
Query: 2098 CPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCEISRCFNHKCQNNGICILKQG--IPECDCTKTVYEGQLCETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPICSKDKCINGGKCVV-VDRSPFCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVDGVMCDYKEPGYAITAFKPPMVSSGIVTSMGFQTFVKTGTLFCYETADDKYWLIKLVNGRLVADINGISFNMKTVVSDGRYHFLKVSRDETNFVISLDHFPFENLLIPTAITSILTLPNNIIIYTKLTLCNSCPDTFNRDR---FQGAIGSA---KSGHVDISKGLKXXXXXXXXXXXXXXXXXLTPVMPLPEIPTIQPCYAGFCKNSGKCLVKNYGPRCDCGISGFTGNQCDQKIM-VIKSVPPNPGYVIITRNPVIATNFDLIRFISESSESSTPLTALITPEGNSIEIKIENQKVFVRINGEAKGPLNDKLIEKNVPNFFKLVNLLGRVTVYVNGTKLGHIVLKE--PLIMKNNSIQISKVLVGANRNADETIKGSLGDFRYNELNLISSNGTFDPNSKQIPNIKLEQWKMIGRK-------MPDINKVRKG--------------SHG----------GVVFTSTKFIIADGFGAGDVVSISNGPIVLGAQLLGAKTIG-VDPFXXXXXXXXXXXXXXXXWAFMN-----------------LIFSRTHVTASGNKLLLIENNDLQISPLLQEKASIQLISGGFQADTNETMIHTMRQNRMDMNKT--SDFFTSNGFNKS--TFGTTGSADFEKIQPVKYASIFAQQDTDLQQPNVFSEEEMKIDCCVMSNNSRYAITGSVAGPPQVWDLNDGFLTHIMDGANQACTSLHLAMNNSVLIGLVT---QNQQPFSLKLLMMWKFPDGQIIDSGYEYMCTTCCVSADGECVILADDM-KDSSITILNLTNQQTRKLVYKAGLVNGDGIQLLKQTKNGQFLIAGFQTFDNSTSY-MVFDMTMQSRKNGVFK-----INANTNCTDFINNNEAVTGTESGELIIWDLNTVQAVRRILISPNFVDNS--ESRNPHKDSLTCVTVSNDGSLLATTGLDATVKVWNMEDEKLLYNLNKHKDEIQSLVWSNDNEMLVSGSLDGSIRIWNVTNGQEMCGFNSNIEITXXXXXXXXXXXXGLGERAGVNKLVMLKILRN 5985
            CP  YC N GRC  +   +  CDC  T + G+ C    P C PN C NG  C +V  N  CNCTG  F G  C    C    C NNG C ++ G   PECDCT T + G  C  P CP  +C N G C     N LP+C C+ T + G +C  PICP NYC+  G C V +   VC C   + G +C+  +C+   C +GG C    DR P C C + ++G  CE PK CP GYC +GG+C M  GMP CNC  T+Y G +C+ PK CP  YC NGG C++    +ICNC    + G  C++   CP  YC  G    +  G++ C+C  TG  G +CD  V+G+  DY++ GY +   KPP+ +     ++GF+T+ ++GT+  + T     W IKL NG +V D NG  +    +V+DG YH + V R   + +++LD+    NL     +T I    +  I YT L +        NR+R   F+GAIG         +D +KG       G  ++ G +  +L P   LP       C   +C N G C V NY  +CDC  +G+ G++C++     I +V  N  Y+II   P   TN D +R   ++  +  P+   ++ +G   EI ++ Q+VFV  N +    L     ++       +V LL R     + T  GH  + +   L+    ++   ++++GA+R    T  G LG F +N   L+S NG     S    N+ +   +  G K       MP   +                   HG          G         I  G GAG V + S GP++L  Q  GA   G ++P++ G+++  + LI ALIWA                      F  T    S        + DL +S       S  LI+      TN T+  T  Q          +  FT+ G +KS   FG     D       +Y      Q  +   PNV++ +++K+DCCV++ NSRY +TGS +GPPQVWD+  G    +M+G    C+ LHLA+N+++L+G V    Q+ +   +  L +W F  G+ ++   E +C+  CVS  GE ++ A    +  SI + +L   Q  + ++   + +   +  +  T   +F++AGF       +Y MVFD+  ++  +GV +      +A    T+ +NN+EAVTGT  GELI+W+L T   VR+  I+     ++   +  PH   +  VT+S D   L T   D  V+VWNM +E+LL+ L  H D++ S+V S D+EM+VSGS DGSIR+W + +G +MC F SNIE+ +V LS DK+ +VGLGER G  KL+M++I+RN
Sbjct: 1736 CPDGYCLNGGRC-TVQNGRPVCDCSGTDYRGDRC--AHPICPPNFCLNGGTCYVVDGNPRCNCTGLNFAGDRCHYPICPVGYCMNNGRCFIRPGATTPECDCTGTGFVGDRCSQPVCPEGYCQNGGICHA-LPNGLPFCDCSYTSYTGDKCETPICPPNYCSGRGTCRVENGRPVCDCQLQYWGPQCQLDVCTTGFCHHGGTCYPGPDRRPHCRCPEGYEGDQCEIPKTCPPGYCYHGGECTMQGGMPVCNCINTDYQGTRCDVPKTCPPGYCRNGGQCTVAGGKYICNCLGTGFQGPTCSDPAACPPGYCHGGICTVLPGGRYVCSCWKTGLSGPRCDGDVNGIYIDYEKTGYMVYELKPPLKTKEDNITVGFKTYAQSGTILDFVTTTGVRWGIKLRNGHIVVDRNGQEYMYPNLVNDGAYHVVTVERKGESMLVTLDNDQLVNL----PMTGITDRSDQSITYTTLFV------GANRNREDIFRGAIGGLYWNGRYPIDEAKG-------GLQVITGEVIYVLLPSFILPGQKPKPTCPPDYCFNGGICYVDNYELKCDCRNTGWQGSRCEKPTRGYIPAVSGNGAYIIIPIVPPKRTNLDRMRIAFQTYTADGPIARFMSQDGRFYEIYMKGQQVFVS-NSKDDIRLISAPYQQCDDGKMHVVTLL-RNGSRFDWTVDGHRTVFDDISLVDSKGALITDEIVLGADRKFKYTFNGVLGAFDWNGRMLVSDNGELSSGS----NVMIVPGRGPGDKDDVVIVLMPHFLQPPVPTTVAPPLPFPTALPGHGVHGGAIVGGPGGGGPLVVPPIGYGDGAGGVFAGS-GPLLL--QAGGAGIFGLINPWLAGLLVCLLPLISALIWACWRCKPGCCPCCVGAGKGAGGKFHDTMDRLSAGLWAAPTDKDLIVS-------SKPLIA------TNGTISQTAHQGNFHPVPPGGASLFTTGGQSKSGYVFGQDRHVDITD----RYDMTMMDQHME-GIPNVYTTDDLKVDCCVLTQNSRYVVTGSASGPPQVWDMQTGEPYKVMNGDELGCSDLHLAVNDTLLVGQVIEDFQSAETTKMHRLQLWNFVTGEQLEMPAEILCSASCVSNAGEHIVAARATPQGQSILVWDLVGNQLTREIHYIPINSKARVSYINITPEDRFVVAGFNNPGTDQAYFMVFDLAAET--SGVVQPKYITFDAKAEATEILNNDEAVTGTRKGELIVWNLLTKMPVRQFSINATLEGDTGITTFPPHDGIIHDVTLSEDRRFLVTASQDRRVRVWNMPEERLLHTLEGHADDVLSVVVSCDSEMVVSGSWDGSIRVWRIKDGSQMCWFTSNIEVLQVKLSRDKRAIVGLGERNGHRKLIMMQIIRN 3059          

HSP 2 Score: 516.924 bits (1330), Expect = 1.604e-145
Identity = 334/1025 (32.59%), Postives = 526/1025 (51.32%), Query Frame = 1
Query:  130 VILTSQPIPVSFT-MPDAMLRLHPWNFAKYSSIELEFHTREPRGILFFVGSSTASTDSIGLEIFNSNVYAFGKLLGKDFR-IKLNPDNIRVSNGKFFKVAIQILATNYLVLKFDDVEIK-EKIPTPGKLEFNSYTYIGGVDTITRLPWKAFSQTGFTGCINYIRINGERFLD-TKQHSKQTEM-QGAKTGVCQTSTARCLPGICGPGKCHERSYNMLDQSKNFYCDCSGTFKSYAYSAVDILRGEPCLIDSQRFQCNTKSYLLYTFDKEK---TTHYDDISIDFQTTNTKEPLFLMKSGTANVINTFLSAEVLAGQVIIIIKXXXXXXXXXXXXXXXXXXXXXDGQWHTLKLSRFAYNVEFYVDEQETISRGELYQSSLEEKFFNKVKEILLGSTTKP--------------PGPDKCTGEIKNFFWNEEDLLGRKNKYGYYSSQLVTEKXXXXXXXXXXXXXXXXCTLKPNHIY-TVLNNIPLTNEGIILFIEFKTKFDGIIWHAVNVFSSEDWMTLLVNSNSIILAYSLPPNEGVHTIEMTRGGILIQDNTWHRVIINLNKPKEILYIHIDDVESLTNEIKLKNSKKELAEMNFISLSLGGISDNSQYTQFYNLLRKKNPEVSKLFSGPDELKFIGCLGDILVINSSYSGNLIQK--PNVNSFPKESL---FCRACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCEISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICPQNYCTKNGNCLVRDDSAVCYCD-EGFTGDKCEKPICSKDKCINGGKCVVVDRSPFCVC-AKDFQGKSCEKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKV 3111
            + L + P+PV+F     +++R   W+F+ + S E+EF T EP G+LFFVG     TD + +EIF+ NVY F   +G  +R I+LNPD  +V+ G   +V ++    +  ++K++  E+  ++     + EF+SYTY G +D  +R PW  +S+  F GCIN+IRIN ++FLD   + ++ T++ +G + GVC+    RC   ICG G+CHERSY    +  NF CDCS + K++     DI R E C  D+     + ++ L+  F+++    TTH DDI++ F+T +   PLF+  S TA     +   E+  G + +   + +++     + F  K+  LND  WHTL++ R A  +   VD       G L     +  F N  ++I +G +                 P   K  GE++NF+WN+ D  G +    +Y++ ++T +  LP  P +PR+P    T      + T+   +     G +  +EFKTK+DG++ HA +  S+    TL++    + L YS+    GVH  E+    I I DN WHRV   L++ K  + + +DD        +L+++      +N ++   GG+ +   +T+   ++R   P               GCLG        +  +L++K    + S+P   +   FCR    ++ +C  +YC N G C+ +++T + C+C  T + G  C+ +  +C PN C NG +C + GNN +C+C GTG+ G  CE+S C    C N GIC ++   P C+C  T Y G  C++  CP ++CLN G C++      P C C+ T + G  C +PIC   YC   G C V++   VC C   G+ G  CE PIC    C NGG CV+    P C C    + G  C++P  C  GYC  GG C + NG P C+C+ T Y G +  +   C   YC+NGG+C I      C+C    Y G  C   + C   YC+NGG C +  G+  C+CS TGY G+ C+  +
Sbjct:  514 ITLHTSPMPVTFMGTQSSVVRFDTWDFSVFHSFEIEFRTFEPNGVLFFVGPDREHTDFVCVEIFDGNVY-FAYGIGDHYRHIQLNPDTRKVNTGTAHRVYVERTPQHRFIVKYNGKEVDVDQGTVRHQAEFSSYTYFGSIDQPSRFPWVVWSRENFAGCINFIRINDDKFLDPASRMNQHTDLSRGIQFGVCKAPDLRCNREICGGGQCHERSYPFF-EPMNFACDCSASDKTFREGVEDIRRSEACNRDAPIVDFDGETVLMIDFERQMNTLTTHTDDINLQFKTESLYAPLFVAVS-TAE--KQYFRVELENGLIKVSTNMNKASKPPRDAEFLLKSPRLNDNTWHTLRIRRRAQFLYISVDNASE-ENGVLIVEIPKGVFNNIAQQIYVGGSMPENYASPPYGNMAGFLPKGTKFVGEMRNFYWNQYDFFGTRKLITHYTTDVLTPRLELPPFPSWPREPIYSITCTSKLEWGTITVPMKAKEAGDMWLLEFKTKYDGVLLHARDD-STGSHFTLMILKGRLHLIYSIGGVTGVH--EIINSPITISDNRWHRVTFGLDRIKGRIVVIVDDSAPEMFGHRLQHNT-----LNTLTFHFGGVPN--IWTKILEIIRLYAPTSLPPGYETRPPALTGCLGGFSTRTDRFLVDLLKKFDAQLESYPSGEIIRGFCR----DLVRCSPDYCLNGGVCFKVSDTVLRCNCTNTGYTGSRCENRITTCPPNYCLNGGVCSLGGNNPVCSCKGTGYYGDRCEMSICTPDYCLNGGICSVENDRPVCNCVNTGYGGARCDSAVCPPNYCLNGGRCVVQAGR--PVCDCSGTAYEGQLCERPICRPGYCRNGGVCRVQNGRPVCDCSGTGYDGQICENPICRPGYCQNGGLCVIEGGRPICDCRGTGYDGPLCDQPI-CRPGYCRNGGVCLVQNGRPVCDCSGTGYDG-QICENPICRPGYCQNGGLCVIEGGRPTCDCRGTGYDGPLCDQPI-CRPGYCRNGGVCLVQNGRPVCDCSGTGYDGQVCENPI 1513          

HSP 3 Score: 262.692 bits (670), Expect = 2.743e-66
Identity = 140/341 (41.06%), Postives = 189/341 (55.43%), Query Frame = 1
Query: 2098 CPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCEISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICPQNYCTKNGNCLVRDDSAVCYCD-EGFTGDKCEKPICSKDKCINGGKCVVVDRSPFCVC-AKDFQGKSCEKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKV 3111
            C   YC+N G C  +   +  CDC  T + G+ C+   P C P  C+NG +C I G    C+C GTG+ G  C+   C    C+N G+C+++ G P CDC+ T Y+GQ+CE P C   +C N G CL+      P C C  TGF G  C++P+CP  YC   G CL+++   VC C   GF G  CE+PIC  D C+NGG+C+V    P C C   +F+G +CE P  C  GYC+ GG+C +VNG P C+C+ T Y G    +   C   +C NGG C + N   IC+C    + G  C   V  PD YC NGG C +  G   C+C+ TGYGG  C+Q +
Sbjct: 1403 CRPGYCRNGGVCL-VQNGRPVCDCSGTGYDGQICE--NPICRPGYCQNGGLCVIEGGRPTCDCRGTGYDGPLCDQPICRPGYCRNGGVCLVQNGRPVCDCSGTGYDGQVCENPICRPGYCQNGGLCLVE--GGRPICDCRGTGFGGALCDQPLCPPGYCQNGGRCLIQNGQPVCDCTLTGFQGRYCEQPICRPDFCLNGGQCIVQGGRPVCDCRGTNFEGTNCETPV-CRPGYCMNGGQCTIVNGRPTCDCSNTGY-GGPLCEQPVCRPGFCLNGGRCIVQNGQPICDCRGTGFVGPHCEQTVCRPD-YCMNGGRCVVQNGAATCDCTNTGYGGPLCEQPI 1735          

HSP 4 Score: 244.202 bits (622), Expect = 1.136e-60
Identity = 132/341 (38.71%), Postives = 183/341 (53.67%), Query Frame = 1
Query: 2098 CPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCEISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICPQNYCTKNGNCLVRDDSAVCYC-DEGFTGDKCEKPICSKDKCINGGKCVVVDRSPFCVC-AKDFQGKSCEKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKV 3111
            C   YC+N G C  +   +  CDC  T + G+ C+   P C P  C+NG +C + G   IC+C GTGF G  C+   C    CQN G C+++ G P CDCT T ++G+ CE P C  DFCLN G C++      P C C  T F G  C  P+C   YC   G C + +    C C + G+ G  CE+P+C    C+NGG+C+V +  P C C    F G  CE+   C   YC+ GG+C + NG   C+CT T Y G    +   CP+ YC NGG C++ N   +C+CS   Y G+RC + + CP N+C NGG C +  G   CNC+   + G++C   +
Sbjct: 1477 CRPGYCRNGGVCL-VQNGRPVCDCSGTGYDGQVCE--NPICRPGYCQNGGLCLVEGGRPICDCRGTGFGGALCDQPLCPPGYCQNGGRCLIQNGQPVCDCTLTGFQGRYCEQPICRPDFCLNGGQCIVQ--GGRPVCDCRGTNFEGTNCETPVCRPGYCMNGGQCTIVNGRPTCDCSNTGYGGPLCEQPVCRPGFCLNGGRCIVQNGQPICDCRGTGFVGPHCEQ-TVCRPDYCMNGGRCVVQNGAATCDCTNTGY-GGPLCEQPICPDGYCLNGGRCTVQNGRPVCDCSGTDYRGDRCAHPI-CPPNFCLNGGTCYVVDGNPRCNCTGLNFAGDRCHYPI 1809          
BLAST of notch-1 vs. Ensembl Cavefish
Match: notch1a (neurogenic locus notch homolog protein 1 [Source:NCBI gene;Acc:103034623])

HSP 1 Score: 117.857 bits (294), Expect = 8.762e-26
Identity = 119/368 (32.34%), Postives = 161/368 (43.75%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCT-GTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCE--KPICSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKP-KPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERC----------TNKVGCP-DNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            CQ N+ +C  N C N+G C + +     C+C    + G+ C+     C   PCKNG +C+   + +  +C    G+ G  CE  I+ C    C N G+C+   G  +C C    + G LCET    C  + C N G C+ ++VN    CVC   GF G RC + I  C    C   GNC    +S  C C  GF+G  CE   P C++  C NGG CV    S  CVC   F G  C+     C    CL GG C+   G  +C C             + C    C+NGG C    + F C C++  +TG  C            + G P    C+NGG C        C C   GY G  C ++VD
Sbjct:  760 CQTNINECASNPCLNQGTCID-DVAGYKCNCL-LPYTGDLCESVLAPCSSRPCKNGGVCRESEDYQSFSCACPAGWQGQTCEVDINECVKSPCLNGGVCLNSVGGFQCHCNPG-FTGDLCETDTDDCTPNPCSNGGVCV-DRVNGF-TCVC-VAGFRGERCTEDIDECVSAPCRNGGNCTDCVNSYTCSCPAGFSGINCEINTPDCTESSCFNGGTCVDGINSFSCVCLPGFTGSYCQHDVNECDSRPCLNGGTCQDGFGTYKCTCPHGYTGANCQSLVRWCDSSPCKNGGSCWQKGSSFTCQCAS-GWTGLYCDVPSVSCEVAAQQQGVPVATLCRNGGQCVDVGSTHLCRCQ-AGYTGSYCQEQVD 1119          

HSP 2 Score: 98.5969 bits (244), Expect = 6.963e-20
Identity = 110/394 (27.92%), Postives = 160/394 (40.61%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGICQIVGNNRICNCTGTGFTGFDCEIS--RCFNHKCQNNGICILKQGIPECDCTKTV------------------------------------YEGQLCET--PKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRC--NKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKP-KPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGIC--SIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            CQ +V +C    CQN  +C +    K  C+CK+  F G  C+I    C  NPC  G+C+    +  C C   G+ G  CEI+   C +  C+N G C+ ++    C C K                                      Y G  C      C L+ C N G C+ + VN    C+C   G++   C   +  C  N C  +GNC  + +S +C C+ G+TG  C+  +  C  + C+NGG C  +     C C   F G +C+     C    CL  G C       +CNC               C  + C+NGG+C  S     F C C    + G+ C   +  C  + C NGG C    G F C+C+  G+ G+ C+   D
Sbjct:  497 CQVDVDECASTPCQNGAKCTD-GPNKFTCECKEG-FTGSLCEIDINECASNPCHYGVCKDGLASFTCACR-PGYAGRLCEININECLSQPCRNGGTCLDRENSYTCTCPKGTTGRNCEINVDDCKSKPCDFGKCIDKINGYECLCDPGYTGATCNINIDDCALNPCRNGGTCV-DGVNSF-TCLC-PDGYHDSTCLSQRNECASNPCI-HGNCQDQANSYLCVCEPGWTGRNCDLNLNECLSNPCVNGGTCRDMTNGYICSCRAGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGDLCESVLAPCSSRPCKNGGVCRESEDYQSFSCACP-AGWQGQTCEVDINECVKSPCLNGGVCLNSVGGFQCHCN-PGFTGDLCETDTD 881          

HSP 3 Score: 93.9745 bits (232), Expect = 1.835e-18
Identity = 119/422 (28.20%), Postives = 164/422 (38.86%), Query Frame = 1
Query: 2071 RACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDC--EISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCE--TPKCPLDFCLNNGHCL----------------------LNQVNQLPYCVCNST---GFYGYRCNKP-------------ICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPICS------------KDKCINGGKCVVVDRSPFCVCAKDFQGKSC-EKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG--CPDN-------YCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVDGVMCDYKEP 3141
            + C+ ++ +C K+ C N G C N +     C C    F G+ C+     C PNPC NG +C    N   C C   GF G  C  +I  C +  C+N G C        C C    + G  CE  TP C    C N G C+                      +N+ +  P C+   T   GF  Y+C  P              C  + C   G+C  +  S  C C  G+TG  C+ P  S               C NGG+CV V  +  C C   + G  C E+   C    C  G  C    G   C C    +     ++  +C  + C+NGG C  + N + C+C   +  G  C   V    PD         C NGG C    G +GC CS  GY GE+C+  V+  + D  +P
Sbjct:  836 QTCEVDINECVKSPCLNGGVCLN-SVGGFQCHCNPG-FTGDLCETDTDDCTPNPCSNGGVCVDRVNGFTCVCV-AGFRGERCTEDIDECVSAPCRNGGNCTDCVNSYTCSCPAG-FSGINCEINTPDCTESSCFNGGTCVDGINSFSCVCLPGFTGSYCQHDVNECDSRP-CLNGGTCQDGFGTYKCTCPHGYTGANCQSLVRWCDSSPCKNGGSCWQKGSSFTCQCASGWTGLYCDVPSVSCEVAAQQQGVPVATLCRNGGQCVDVGSTHLCRCQAGYTGSYCQEQVDECVPNPCHNGATCTDYLGGYTCECVAGYHGVNCSKEINECVSQPCQNGGTCIDLVNSYKCSCPRGT-QGVHCEIDVDDCSPDTDPLTGEPRCFNGGRCVDRVGGYGCVCS-PGYVGERCEGDVNECLSDPCDP 1250          

HSP 4 Score: 92.0485 bits (227), Expect = 7.105e-18
Identity = 106/360 (29.44%), Postives = 144/360 (40.00%), Query Frame = 1
Query: 2092 KKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKN-GICQIVGNNRICNCTGTGFTGFDC--EISRCF--NHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI----CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSC-EKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSI--INNVFICNCSNVSYTGERCTNKV---GCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
              C  + C+N G C  I     +C C    + G+ C    P C  NPC N G C    ++ IC C    F G  C  +++ C      C+N G+C+ + G   C C    + G  CE P   C    C N G C+  Q +   Y      GF G  C   I  C Q+ C   G C+   ++  C+CD+ +TG  C + +     S + C NGG C        CVC   + G  C E    C    C +G  C        C C      G  C     C    C+ G  C    +N   IC C    YTG  C   +       N C++GG C   +G F C C L GY G +C+  V+
Sbjct:   76 HACMNSPCRNGGSCSLITLATFSCRCPPG-WSGKTCQQADP-CASNPCANGGQCSAFESHFICTCP-PNFHGQTCRQDVNECALSPSPCRNGGVCVNEVGSYRCRCPAE-FAGTHCERPFHPCHPSPCTNGGTCV--QTSDTGYTCSCLPGFNGQDCEHNIDDCVQHACENGGKCMDGVNTYNCHCDKHWTGQYCTEDVDECELSPNACQNGGTCHNTVGGFHCVCVNGWSGDDCSENIDDCASAACYHGATCHDRVASFYCECPH-GRTGLLCHLDDACISNPCQKGSNCDTNPVNGKAICTCP-PGYTGSACNQDIDECSLGANPCEHGGRCLNTKGSFQCKC-LKGYEGPRCEMDVN 426          

HSP 5 Score: 83.5741 bits (205), Expect = 2.713e-15
Identity = 109/368 (29.62%), Postives = 146/368 (39.67%), Query Frame = 1
Query: 2071 RACQENVKKCP--KNYCQNKGRCYN-INETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG--ICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLC--ETPKCPL--DFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCE-KPICSKDKCINGGKCVV--VDRSPFCVCAKDFQGKSCEKP-KPCPVGY--CLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCT-NKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            + C+++V +C    + C+N G C N +   +  C     +F G  C+     C P+PC NG    Q       C+C   GF G DCE  I  C  H C+N G C+       C C K  + GQ C  +  +C L  + C N G C  N V    +CVC   G+ G  C++ I  C    C     C  R  S  C C  G TG  C     C  + C  G  C    V+    C C   + G +C +    C +G   C +GG+C    G  +C C +     +      +C    C+N   C      F C C    Y GE C  N   C    C N G C      F C C   G+ G  C   VD
Sbjct:  145 QTCRQDVNECALSPSPCRNGGVCVNEVGSYRCRC---PAEFAGTHCERPFHPCHPSPCTNGGTCVQTSDTGYTCSCL-PGFNGQDCEHNIDDCVQHACENGGKCMDGVNTYNCHCDKH-WTGQYCTEDVDECELSPNACQNGGTC-HNTVGGF-HCVC-VNGWSGDDCSENIDDCASAACYHGATCHDRVASFYCECPHGRTGLLCHLDDACISNPCQKGSNCDTNPVNGKAICTCPPGYTGSACNQDIDECSLGANPCEHGGRCLNTKGSFQCKCLKGYEGPRCEMDVNECKSNPCQNDATCLDQIGGFHCICM-PGYEGEFCQINTDDCASQPCLNNGKCIDKINSFYCECP-KGFSGSLCQVDVD 502          

HSP 6 Score: 81.2629 bits (199), Expect = 1.232e-14
Identity = 97/329 (29.48%), Postives = 127/329 (38.60%), Query Frame = 1
Query: 2176 TQFYGEFCDIKRPSCDPNPCKN-GIC--QIVGNNRICNCTGTGFTGFDCEISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETP---KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKP-ICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI----CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKP-KPCPVGYCLYGGKCRMVNGMP-RCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG---CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
              F G  C I  P C P+PC+N G+C  +  GN+            F CE              C+L             + G LC TP    C    C N G C L  +     C C   G+ G  C +   C  N C   G C   +   +C C   F G  C + +     S   C NGG CV    S  C C  +F G  CE+P  PC    C  GG C   +     C+C               C +  CENGG C    N + C+C +  +TG+ CT  V       N C+NGG C    G F C C + G+ G+ C + +D
Sbjct:   22 ADFVGPQCQIPNP-CSPSPCRNGGVCRPRTQGND----------VDFTCE--------------CMLG------------FSGPLCLTPVNHACMNSPCRNGGSCSLITLATF-SCRC-PPGWSGKTCQQADPCASNPCANGGQCSAFESHFICTCPPNFHGQTCRQDVNECALSPSPCRNGGVCVNEVGSYRCRCPAEFAGTHCERPFHPCHPSPCTNGGTCVQTSDTGYTCSCLPGFNGQDCEHNIDDCVQHACENGGKCMDGVNTYNCHC-DKHWTGQYCTEDVDECELSPNACQNGGTCHNTVGGFHCVC-VNGWSGDDCSENID 309          

HSP 7 Score: 73.9442 bits (180), Expect = 2.027e-12
Identity = 103/401 (25.69%), Postives = 144/401 (35.91%), Query Frame = 1
Query: 2071 RACQENVKKCPKNYCQNKGRCYN-INETKIACDCKKTQFYGEFC--DIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCE-TPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI----CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI----------------------------------------CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCE-KPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            + C+ N+  C ++ C+N G+C + +N     CD     + G++C  D+      PN C+NG  C        C C   G++G DC   I  C +  C +   C  +     C+C      G LC     C  + C    +C  N VN    C C   G+ G  CN+ I       N C   G CL    S  C C +G+ G +CE  +                                        C+   C+N GKC+    S +C C K F G  C+     C    C  G KC        C C +  + G  CE           + G+C      F C C    Y G  C   +  C    C+NGG C      + C C   G  G  C+  VD
Sbjct:  224 QDCEHNIDDCVQHACENGGKCMDGVNTYNCHCD---KHWTGQYCTEDVDECELSPNACQNGGTCHNTVGGFHCVCV-NGWSGDDCSENIDDCASAACYHGATCHDRVASFYCECPHG-RTGLLCHLDDACISNPCQKGSNCDTNPVNGKAICTC-PPGYTGSACNQDIDECSLGANPCEHGGRCLNTKGSFQCKCLKGYEGPRCEMDVNECKSNPCQNDATCLDQIGGFHCICMPGYEGEFCQINTDDCASQPCLNNGKCIDKINSFYCECPKGFSGSLCQVDVDECASTPCQNGAKCTDGPNKFTCECKE-GFTGSLCEIDINECASNPCHYGVCKDGLASFTCAC-RPGYAGRLCEININECLSQPCRNGGTCLDRENSYTCTCP-KGTTGRNCEINVD 615          

HSP 8 Score: 73.9442 bits (180), Expect = 2.398e-12
Identity = 88/304 (28.95%), Postives = 119/304 (39.14%), Query Frame = 1
Query: 2113 CQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDC--EISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCE--TPKCPLDF--------CLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNG--NCLVRDDSAVCYCDE--------------------------------------GFTGDKCE--KPICSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEK--PKPCPVGYCLYGGKCRMVNGMP--RCNC 2841
            C+N G+C ++  T + C C+   + G +C  +   C PNPC NG  C        C C   G+ G +C  EI+ C +  CQN G CI      +C C +   +G  CE     C  D         C N G C +++V     CVC S G+ G RC   +  C  + C  NG  NC+   +S  C C                                        GF+G  CE     C   +C NG  CV    SP C+C   F G  C+     PC    C  GG C+ ++  P  RC C
Sbjct: 1088 CRNGGQCVDVGSTHL-CRCQAG-YTGSYCQEQVDECVPNPCHNGATCTDYLGGYTCECV-AGYHGVNCSKEINECVSQPCQNGGTCIDLVNSYKCSCPRGT-QGVHCEIDVDDCSPDTDPLTGEPRCFNGGRC-VDRVGGY-GCVC-SPGYVGERCEGDVNECLSDPCDPNGSYNCVQLVNSYRCECRTGYTGMYTYTNMCNISLWPYFTGGKYCTLLKLQKNRKSIGFSGSSCEYNSQSCGSLRCRNGATCVSGHLSPRCLCPPGFSGHECQNRLDSPCLSNPCYNGGTCQPISDAPFFRCLC 1384          

HSP 9 Score: 66.2402 bits (160), Expect = 4.585e-10
Identity = 105/400 (26.25%), Postives = 148/400 (37.00%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKN-GICQIVGNNRICNCTGTGFTGF-------DCEISRCFNHKCQNNGICILKQGIPEC---------DCTKTV--------YEGQLCETP------KCPL----------DFCLNN-----GHCLLNQVNQLPYCVCNSTGFYGYRCNKPI----CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCE-KPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            C+     C  + C N G C   ++T   C C    F G+ C+     C  + C+N G C    N   C+C    +TG        +CE+S    + CQN G C    G   C         DC++ +        Y G  C         +CP           D C++N      +C  N VN    C C   G+ G  CN+ I       N C   G CL    S  C C +G+ G +CE  +  C  + C N   C+       C+C   ++G+ C+     C    CL  GKC        C C +            +C    C+NG  C+   N F C C    +TG  C   +  C  N C   G C+     F C C   GY G  C+  ++
Sbjct:  187 CERPFHPCHPSPCTNGGTCVQTSDTGYTCSCLPG-FNGQDCEHNIDDCVQHACENGGKCMDGVNTYNCHCD-KHWTGQYCTEDVDECELSP---NACQNGGTCHNTVGGFHCVCVNGWSGDDCSENIDDCASAACYHGATCHDRVASFYCECPHGRTGLLCHLDDACISNPCQKGSNCDTNPVNGKAICTC-PPGYTGSACNQDIDECSLGANPCEHGGRCLNTKGSFQCKCLKGYEGPRCEMDVNECKSNPCQNDATCLDQIGGFHCICMPGYEGEFCQINTDDCASQPCLNNGKCIDKINSFYCECPKGFSGSLCQVDVDECASTPCQNGAKCTDGPNKFTCECKE-GFTGSLCEIDINECASNPCHY-GVCKDGLASFTCACR-PGYAGRLCEININ 577          
BLAST of notch-1 vs. Ensembl Cavefish
Match: notch1a (neurogenic locus notch homolog protein 1 [Source:NCBI gene;Acc:103034623])

HSP 1 Score: 117.087 bits (292), Expect = 1.914e-25
Identity = 119/368 (32.34%), Postives = 161/368 (43.75%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCT-GTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCE--KPICSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKP-KPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERC----------TNKVGCP-DNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            CQ N+ +C  N C N+G C + +     C+C    + G+ C+     C   PCKNG +C+   + +  +C    G+ G  CE  I+ C    C N G+C+   G  +C C    + G LCET    C  + C N G C+ ++VN    CVC   GF G RC + I  C    C   GNC    +S  C C  GF+G  CE   P C++  C NGG CV    S  CVC   F G  C+     C    CL GG C+   G  +C C             + C    C+NGG C    + F C C++  +TG  C            + G P    C+NGG C        C C   GY G  C ++VD
Sbjct:  785 CQTNINECASNPCLNQGTCID-DVAGYKCNCL-LPYTGDLCESVLAPCSSRPCKNGGVCRESEDYQSFSCACPAGWQGQTCEVDINECVKSPCLNGGVCLNSVGGFQCHCNPG-FTGDLCETDTDDCTPNPCSNGGVCV-DRVNGF-TCVC-VAGFRGERCTEDIDECVSAPCRNGGNCTDCVNSYTCSCPAGFSGINCEINTPDCTESSCFNGGTCVDGINSFSCVCLPGFTGSYCQHDVNECDSRPCLNGGTCQDGFGTYKCTCPHGYTGANCQSLVRWCDSSPCKNGGSCWQKGSSFTCQCAS-GWTGLYCDVPSVSCEVAAQQQGVPVATLCRNGGQCVDVGSTHLCRCQ-AGYTGSYCQEQVD 1144          

HSP 2 Score: 97.4413 bits (241), Expect = 1.480e-19
Identity = 110/394 (27.92%), Postives = 160/394 (40.61%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGICQIVGNNRICNCTGTGFTGFDCEIS--RCFNHKCQNNGICILKQGIPECDCTKTV------------------------------------YEGQLCET--PKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRC--NKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKP-KPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGIC--SIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            CQ +V +C    CQN  +C +    K  C+CK+  F G  C+I    C  NPC  G+C+    +  C C   G+ G  CEI+   C +  C+N G C+ ++    C C K                                      Y G  C      C L+ C N G C+ + VN    C+C   G++   C   +  C  N C  +GNC  + +S +C C+ G+TG  C+  +  C  + C+NGG C  +     C C   F G +C+     C    CL  G C       +CNC               C  + C+NGG+C  S     F C C    + G+ C   +  C  + C NGG C    G F C+C+  G+ G+ C+   D
Sbjct:  522 CQVDVDECASTPCQNGAKCTD-GPNKFTCECKEG-FTGSLCEIDINECASNPCHYGVCKDGLASFTCACR-PGYAGRLCEININECLSQPCRNGGTCLDRENSYTCTCPKGTTGRNCEINVDDCKSKPCDFGKCIDKINGYECLCDPGYTGATCNINIDDCALNPCRNGGTCV-DGVNSF-TCLC-PDGYHDSTCLSQRNECASNPCI-HGNCQDQANSYLCVCEPGWTGRNCDLNLNECLSNPCVNGGTCRDMTNGYICSCRAGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGDLCESVLAPCSSRPCKNGGVCRESEDYQSFSCACP-AGWQGQTCEVDINECVKSPCLNGGVCLNSVGGFQCHCN-PGFTGDLCETDTD 906          

HSP 3 Score: 92.8189 bits (229), Expect = 3.707e-18
Identity = 119/422 (28.20%), Postives = 164/422 (38.86%), Query Frame = 1
Query: 2071 RACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDC--EISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCE--TPKCPLDFCLNNGHCL----------------------LNQVNQLPYCVCNST---GFYGYRCNKP-------------ICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPICS------------KDKCINGGKCVVVDRSPFCVCAKDFQGKSC-EKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG--CPDN-------YCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVDGVMCDYKEP 3141
            + C+ ++ +C K+ C N G C N +     C C    F G+ C+     C PNPC NG +C    N   C C   GF G  C  +I  C +  C+N G C        C C    + G  CE  TP C    C N G C+                      +N+ +  P C+   T   GF  Y+C  P              C  + C   G+C  +  S  C C  G+TG  C+ P  S               C NGG+CV V  +  C C   + G  C E+   C    C  G  C    G   C C    +     ++  +C  + C+NGG C  + N + C+C   +  G  C   V    PD         C NGG C    G +GC CS  GY GE+C+  V+  + D  +P
Sbjct:  861 QTCEVDINECVKSPCLNGGVCLN-SVGGFQCHCNPG-FTGDLCETDTDDCTPNPCSNGGVCVDRVNGFTCVCV-AGFRGERCTEDIDECVSAPCRNGGNCTDCVNSYTCSCPAG-FSGINCEINTPDCTESSCFNGGTCVDGINSFSCVCLPGFTGSYCQHDVNECDSRP-CLNGGTCQDGFGTYKCTCPHGYTGANCQSLVRWCDSSPCKNGGSCWQKGSSFTCQCASGWTGLYCDVPSVSCEVAAQQQGVPVATLCRNGGQCVDVGSTHLCRCQAGYTGSYCQEQVDECVPNPCHNGATCTDYLGGYTCECVAGYHGVNCSKEINECVSQPCQNGGTCIDLVNSYKCSCPRGT-QGVHCEIDVDDCSPDTDPLTGEPRCFNGGRCVDRVGGYGCVCS-PGYVGERCEGDVNECLSDPCDP 1275          

HSP 4 Score: 92.8189 bits (229), Expect = 4.101e-18
Identity = 98/314 (31.21%), Postives = 132/314 (42.04%), Query Frame = 1
Query: 2230 PCKNG-ICQIVGNNRI-CNCTGTGFTGFDCEISR-CFNHKCQNNGICILKQGIPECDCT---KTVYEGQLCETP---KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKP-ICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI----CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKP-KPCPVGYCLYGGKCRMVNGMP-RCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG---CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            PC+NG  C++V N ++ C C    F G  C+I   C    C+N G+C  +    + D T      + G LC TP    C    C N G C L  +     C C   G+ G  C +   C  N C   G C   +   +C C   F G  C + +     S   C NGG CV    S  C C  +F G  CE+P  PC    C  GG C   +     C+C               C +  CENGG C    N + C+C +  +TG+ CT  V       N C+NGG C    G F C C + G+ G+ C + +D
Sbjct:   26 PCQNGGTCELVANGQVACRCPAD-FVGPQCQIPNPCSPSPCRNGGVCRPRTQGNDVDFTCECMLGFSGPLCLTPVNHACMNSPCRNGGSCSLITLATF-SCRC-PPGWSGKTCQQADPCASNPCANGGQCSAFESHFICTCPPNFHGQTCRQDVNECALSPSPCRNGGVCVNEVGSYRCRCPAEFAGTHCERPFHPCHPSPCTNGGTCVQTSDTGYTCSCLPGFNGQDCEHNIDDCVQHACENGGKCMDGVNTYNCHC-DKHWTGQYCTEDVDECELSPNACQNGGTCHNTVGGFHCVC-VNGWSGDDCSENID 334          

HSP 5 Score: 90.8929 bits (224), Expect = 1.575e-17
Identity = 106/360 (29.44%), Postives = 144/360 (40.00%), Query Frame = 1
Query: 2092 KKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKN-GICQIVGNNRICNCTGTGFTGFDC--EISRCF--NHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI----CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSC-EKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSI--INNVFICNCSNVSYTGERCTNKV---GCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
              C  + C+N G C  I     +C C    + G+ C    P C  NPC N G C    ++ IC C    F G  C  +++ C      C+N G+C+ + G   C C    + G  CE P   C    C N G C+  Q +   Y      GF G  C   I  C Q+ C   G C+   ++  C+CD+ +TG  C + +     S + C NGG C        CVC   + G  C E    C    C +G  C        C C      G  C     C    C+ G  C    +N   IC C    YTG  C   +       N C++GG C   +G F C C L GY G +C+  V+
Sbjct:  101 HACMNSPCRNGGSCSLITLATFSCRCPPG-WSGKTCQQADP-CASNPCANGGQCSAFESHFICTCP-PNFHGQTCRQDVNECALSPSPCRNGGVCVNEVGSYRCRCPAE-FAGTHCERPFHPCHPSPCTNGGTCV--QTSDTGYTCSCLPGFNGQDCEHNIDDCVQHACENGGKCMDGVNTYNCHCDKHWTGQYCTEDVDECELSPNACQNGGTCHNTVGGFHCVCVNGWSGDDCSENIDDCASAACYHGATCHDRVASFYCECPH-GRTGLLCHLDDACISNPCQKGSNCDTNPVNGKAICTCP-PGYTGSACNQDIDECSLGANPCEHGGRCLNTKGSFQCKC-LKGYEGPRCEMDVN 451          

HSP 6 Score: 84.3445 bits (207), Expect = 1.345e-15
Identity = 86/266 (32.33%), Postives = 116/266 (43.61%), Query Frame = 1
Query: 2113 CQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDC--EISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCE--TPKCPLDF--------CLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNG--NCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSP---FCVCAKDFQGKSCE-KPKPCPVGYCLYGGKCRMVNGMPRCNC 2841
            C+N G+C ++  T + C C+   + G +C  +   C PNPC NG  C        C C   G+ G +C  EI+ C +  CQN G CI      +C C +   +G  CE     C  D         C N G C +++V     CVC S G+ G RC   +  C  + C  NG  NC+   +S  C C  G+TG +C+     C    C NGG C V   +     C C   F G SCE   + C    C  G  C   +  PRC C
Sbjct: 1113 CRNGGQCVDVGSTHL-CRCQAG-YTGSYCQEQVDECVPNPCHNGATCTDYLGGYTCECV-AGYHGVNCSKEINECVSQPCQNGGTCIDLVNSYKCSCPRGT-QGVHCEIDVDDCSPDTDPLTGEPRCFNGGRC-VDRVGGY-GCVC-SPGYVGERCEGDVNECLSDPCDPNGSYNCVQLVNSYRCECRTGYTGQRCDTVFDGCKDKPCKNGGTCAVASNTKHGYICKCPPGFSGSSCEYNSQSCGSLRCRNGATCVSGHLSPRCLC 1371          

HSP 7 Score: 82.4185 bits (202), Expect = 6.057e-15
Identity = 109/368 (29.62%), Postives = 146/368 (39.67%), Query Frame = 1
Query: 2071 RACQENVKKCP--KNYCQNKGRCYN-INETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG--ICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLC--ETPKCPL--DFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCE-KPICSKDKCINGGKCVV--VDRSPFCVCAKDFQGKSCEKP-KPCPVGY--CLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCT-NKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            + C+++V +C    + C+N G C N +   +  C     +F G  C+     C P+PC NG    Q       C+C   GF G DCE  I  C  H C+N G C+       C C K  + GQ C  +  +C L  + C N G C  N V    +CVC   G+ G  C++ I  C    C     C  R  S  C C  G TG  C     C  + C  G  C    V+    C C   + G +C +    C +G   C +GG+C    G  +C C +     +      +C    C+N   C      F C C    Y GE C  N   C    C N G C      F C C   G+ G  C   VD
Sbjct:  170 QTCRQDVNECALSPSPCRNGGVCVNEVGSYRCRC---PAEFAGTHCERPFHPCHPSPCTNGGTCVQTSDTGYTCSCL-PGFNGQDCEHNIDDCVQHACENGGKCMDGVNTYNCHCDKH-WTGQYCTEDVDECELSPNACQNGGTC-HNTVGGF-HCVC-VNGWSGDDCSENIDDCASAACYHGATCHDRVASFYCECPHGRTGLLCHLDDACISNPCQKGSNCDTNPVNGKAICTCPPGYTGSACNQDIDECSLGANPCEHGGRCLNTKGSFQCKCLKGYEGPRCEMDVNECKSNPCQNDATCLDQIGGFHCICM-PGYEGEFCQINTDDCASQPCLNNGKCIDKINSFYCECP-KGFSGSLCQVDVD 527          

HSP 8 Score: 72.7886 bits (177), Expect = 4.372e-12
Identity = 103/399 (25.81%), Postives = 143/399 (35.84%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYN-INETKIACDCKKTQFYGEFC--DIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCE-TPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI----CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI----------------------------------------CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCE-KPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            C+ N+  C ++ C+N G+C + +N     CD     + G++C  D+      PN C+NG  C        C C   G++G DC   I  C +  C +   C  +     C+C      G LC     C  + C    +C  N VN    C C   G+ G  CN+ I       N C   G CL    S  C C +G+ G +CE  +                                        C+   C+N GKC+    S +C C K F G  C+     C    C  G KC        C C +  + G  CE           + G+C      F C C    Y G  C   +  C    C+NGG C      + C C   G  G  C+  VD
Sbjct:  251 CEHNIDDCVQHACENGGKCMDGVNTYNCHCD---KHWTGQYCTEDVDECELSPNACQNGGTCHNTVGGFHCVCV-NGWSGDDCSENIDDCASAACYHGATCHDRVASFYCECPHG-RTGLLCHLDDACISNPCQKGSNCDTNPVNGKAICTC-PPGYTGSACNQDIDECSLGANPCEHGGRCLNTKGSFQCKCLKGYEGPRCEMDVNECKSNPCQNDATCLDQIGGFHCICMPGYEGEFCQINTDDCASQPCLNNGKCIDKINSFYCECPKGFSGSLCQVDVDECASTPCQNGAKCTDGPNKFTCECKE-GFTGSLCEIDINECASNPCHYGVCKDGLASFTCAC-RPGYAGRLCEININECLSQPCRNGGTCLDRENSYTCTCP-KGTTGRNCEINVD 640          

HSP 9 Score: 65.0846 bits (157), Expect = 1.031e-9
Identity = 105/400 (26.25%), Postives = 148/400 (37.00%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKN-GICQIVGNNRICNCTGTGFTGF-------DCEISRCFNHKCQNNGICILKQGIPEC---------DCTKTV--------YEGQLCETP------KCPL----------DFCLNN-----GHCLLNQVNQLPYCVCNSTGFYGYRCNKPI----CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCE-KPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            C+     C  + C N G C   ++T   C C    F G+ C+     C  + C+N G C    N   C+C    +TG        +CE+S    + CQN G C    G   C         DC++ +        Y G  C         +CP           D C++N      +C  N VN    C C   G+ G  CN+ I       N C   G CL    S  C C +G+ G +CE  +  C  + C N   C+       C+C   ++G+ C+     C    CL  GKC        C C +            +C    C+NG  C+   N F C C    +TG  C   +  C  N C   G C+     F C C   GY G  C+  ++
Sbjct:  212 CERPFHPCHPSPCTNGGTCVQTSDTGYTCSCLPG-FNGQDCEHNIDDCVQHACENGGKCMDGVNTYNCHCD-KHWTGQYCTEDVDECELSP---NACQNGGTCHNTVGGFHCVCVNGWSGDDCSENIDDCASAACYHGATCHDRVASFYCECPHGRTGLLCHLDDACISNPCQKGSNCDTNPVNGKAICTC-PPGYTGSACNQDIDECSLGANPCEHGGRCLNTKGSFQCKCLKGYEGPRCEMDVNECKSNPCQNDATCLDQIGGFHCICMPGYEGEFCQINTDDCASQPCLNNGKCIDKINSFYCECPKGFSGSLCQVDVDECASTPCQNGAKCTDGPNKFTCECKE-GFTGSLCEIDINECASNPCHY-GVCKDGLASFTCACR-PGYAGRLCEININ 602          

HSP 10 Score: 56.225 bits (134), Expect = 4.448e-7
Identity = 52/166 (31.33%), Postives = 66/166 (39.76%), Query Frame = 1
Query: 2638 GDKCEKPICSKDKCINGGKC-VVVDRSPFCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXX-----XXXXXXXXXXYCENGGICSIIN-NVFICNCSNVSYTGERCTNKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            G +C +P      C NGG C +V +    C C  DF G  C+ P PC    C  GG CR        + T    +G             C    C NGG CS+I    F C C    ++G+ C     C  N C NGG C      F C C    + G+ C Q V+
Sbjct:   20 GLRCSEP------CQNGGTCELVANGQVACRCPADFVGPQCQIPNPCSPSPCRNGGVCRPRTQGNDVDFTCECMLGFSGPLCLTPVNHACMNSPCRNGGSCSLITLATFSCRCP-PGWSGKTCQQADPCASNPCANGGQCSAFESHFICTCP-PNFHGQTCRQDVN 177          
BLAST of notch-1 vs. Ensembl Cavefish
Match: ENSAMXT00000055435.1 (protein crumbs homolog 2-like [Source:NCBI gene;Acc:103036258])

HSP 1 Score: 103.605 bits (257), Expect = 1.653e-21
Identity = 119/480 (24.79%), Postives = 192/480 (40.00%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCEIS--RCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCET--PKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSA----------------VCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVS-----YTGERCTNKV-GCPDNYCKNGGAC----EIHRGKFGCNCSLTGYGGEQCDQKVDGVMCDYKEPGYAITAF-------KPPMVSSGIVTSMGFQTFVKTGTLFCYETADDKYWLIKLVNGRL----VADINGISFNMKT--VVSDGRYHFLKVS 3372
            C+ ++ +C    C+N G C N  +  I C+C    + G  C+++   C+ +PC+NG  C  +     C+C   GF+G +CEI+   C +  CQN G C       +CDC  + Y G LCE   P+C  D C +   C   +  +   C C   G+ G  C   I  C    C   G C    D                  VC C  G+TG+ C   I  C  + C NGG+C        C+CA  ++G  CE                     +  C                      C+NGG+C  +   + CNC   S     + G +CT ++ GC ++ C+NG  C    +  + +  C C+  G+  + C          + +PGY +          + P     +   + F+T +    LF +    D +  ++LV G L     +  +G+S  + +  + +DG +H + VS
Sbjct:  220 CEIDINECASRPCENNGTCVNGKDRYI-CECL-LGYTGTNCEVEVDECESDPCENGATCIDLVGLYTCDCV-KGFSGLNCEINIDECESAPCQNGGTCQDLVDSFKCDCGDSGYMGDLCEEDIPECASDPCQHGATC--EEGTKEYTCTC-WPGYEGQNCEVDIDECVDAPCENGGECFENSDPMQWTSDWTFSYATAAGYVCQCQPGYTGETCSVNIDECVSEPCHNGGQCEDRVNGYVCICADGYRGVECEVD-------------------IDECE------------------SAPCQNGGVCEDLVGDYECNCEKASRGLQAWGGRQCTVELLGCLNHQCQNGATCRPWLDGDKHRHTCLCA-PGFYDDLCST---ATTFSFSQPGYFLLEVSVEERKKRSPETEHPLQVCLRFRTTLPDRLLF-FRGNSDHFLSLELVRGALRGWAESKEDGVSLQVTSTDLANDGEWHEVCVS 651          

HSP 2 Score: 88.5817 bits (218), Expect = 7.684e-17
Identity = 98/361 (27.15%), Postives = 146/361 (40.44%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIA-CDCKKTQFYGEFCDIKRPSCDPNPCKNGICQIVGNNRIC----------NCTGT-----------------GFTGFDC--EISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCPLDFCLN----NGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCE-KPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXX-XXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGAC 3036
            C E+ +KC  + CQN   C +  +  +  C     ++ G+ C+    +C    C+  + ++   N  C           C G                  G  G DC   I+ C +  C NN  C  +     C+C    Y G+ CE     ++ CL+    NG   ++ +N+  +C C   G+ GY C   I  C    C  NG C+   D  +C C  G+TG  CE  +  C  D C NG  C+ +     C C K F G +CE     C    C  GG C+ +    +C+C  + YMG    E   +C    C++G  C      + C C    Y G+ C   +  C D  C+NGG C
Sbjct:   38 CSESSEKCVSSPCQNGATCVDTMDDYVCLCSRDGVRYMGKDCEELYDACVFAECEGCVSELGTGNFTCPAEVDECASDPCIGARTECLKEPDGFLCLCPDGLGGDDCTARITDCVDQPCLNNATCRRQLDGFVCECAPG-YRGEHCEE---DINECLSHPCQNGAICMDGINEY-HCFC-VPGYQGYNCEIDINECASRPCENNGTCVNGKDRYICECLLGYTGTNCEVEVDECESDPCENGATCIDLVGLYTCDCVKGFSGLNCEINIDECESAPCQNGGTCQDLVDSFKCDCGDSGYMGDLCEEDIPECASDPCQHGATCEEGTKEYTCTCWP-GYEGQNCEVDIDECVDAPCENGGEC 391          

HSP 3 Score: 76.2554 bits (186), Expect = 4.171e-13
Identity = 90/319 (28.21%), Postives = 128/319 (40.13%), Query Frame = 1
Query: 2194 FCDIKRPSCDPNPCKNG-ICQIVGNNRICNCT--GTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCE-KPKPCPVGYCLYGGKCRMVNGMPR--CNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCT-NKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKV 3111
            FC      C  +PC+NG  C    ++ +C C+  G  + G DCE     C   +C+    C+ + G     C   V E        C  D C+      L + +    C+C   G  G  C   I  C    C  N  C  + D  VC C  G+ G+ CE+ I  C    C NG  C+       C C   +QG +CE     C    C   G C  VNG  R  C C           +  +C    CENG  C  +  ++ C+C    ++G  C  N   C    C+NGG C+     F C+C  +GY G+ C++ +
Sbjct:   37 FCSESSEKCVSSPCQNGATCVDTMDDYVCLCSRDGVRYMGKDCEELYDACVFAECEG---CVSELGTGNFTCPAEVDE--------CASDPCIGARTECLKEPDGF-LCLC-PDGLGGDDCTARITDCVDQPCLNNATCRRQLDGFVCECAPGYRGEHCEEDINECLSHPCQNGAICMDGINEYHCFCVPGYQGYNCEIDINECASRPCENNGTC--VNGKDRYICECLLGYTGTNCEVEVDECESDPCENGATCIDLVGLYTCDCVK-GFSGLNCEINIDECESAPCQNGGTCQDLVDSFKCDCGDSGYMGDLCEEDI 339          

HSP 4 Score: 62.3882 bits (150), Expect = 5.463e-9
Identity = 81/358 (22.63%), Postives = 130/358 (36.31%), Query Frame = 1
Query: 1612 LLVNSNSIILAYSLPPNEGVHTIEMTRGGILIQDNTWHRVIINLNKPKEILYIHIDDVESLTNEIKLKNSKKELAEMNFISLSLGGISDNSQYTQFYNLLRKKNPEVSKLFSGPDELKFIGCLGDILVINSSYSGNLIQKPNVNSFPKESLFCRACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCET----PKCPLDFCLNNGHCLLNQVNQLPY---CVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCE 2652
            LL+     ++   L     V  +  T G   + D  WH +++++  P++   + +  V+ +   +   ++ + +  M F+S     ++    YT    L+R                  +G  G  L     +      +       +  L C         C    CQ+ G C ++      C C    + G  C+I    C   PC +G C+       C C   GF G  C+  +  C +  CQN   C+       C C +  Y G+ C+      KC    C++ G C        P+   C+C + G  G RC   I  C  N C   G CL R     C C  GF+G  CE
Sbjct: 1081 LLIGLLDGVVRAELHGENSVEPVVFT-GSQRVTDGLWHHLVVSMEHPEQDASLWVISVDGI---MDGSSAPEHIESMGFLSDVTSEVALAESYTGCLGLVR------------------VG--GTYLPFTDDFVAPQAARFRRRRGERARLGCVG----SSVCRPQPCQHGGTCEDLFH-HFHCACP-LGWEGLTCEIDTDECASGPCVHGNCRDKLGGFECECE-PGFGGATCDEDLDECKDSPCQNRATCVDGVNQYSCICARG-YSGKQCQWNHPPQKCADLECVSGGVC-----RDAPWGAECIC-APGLTGRRCEIEINECMSNPCLNGGTCLDRLSFFQCVCAAGFSGPYCE 1400          
BLAST of notch-1 vs. Ensembl Cavefish
Match: ENSAMXT00000020429.2 (protein crumbs homolog 2-like [Source:NCBI gene;Acc:103036258])

HSP 1 Score: 103.605 bits (257), Expect = 1.692e-21
Identity = 119/480 (24.79%), Postives = 190/480 (39.58%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCEIS--RCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCET--PKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSA----------------VCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVS-----YTGERCTNKV-GCPDNYCKNGGAC----EIHRGKFGCNCSLTGYGGEQCDQKVDGVMCDYKEPGYAITAF-------KPPMVSSGIVTSMGFQTFVKTGTLFCYETADDKYWLIKLVNGRL----VADINGISFNMKT--VVSDGRYHFLKVS 3372
            C+ ++ +C    C+N G C N  +  I C+C    + G  C+++   C+ +PC+NG  C  +     C+C   GF+G +CEI+   C +  CQN G C       +CDC  + Y G LCE   P+C  D C +   C   +  +   C C   G+ G  C   I  C    C   G C    D                  VC C  G+TG+ C   I  C  + C NGG+C        C+CA  ++G  CE                     +  C                      C+NGG+C  +   + CNC   S     + G +CT ++ GC ++ C+NG  C    +  + +  C C+   Y     D         + +PGY +          + P     +   + F+T +    LF +    D +  ++LV G L     +  +G+S  + +  + +DG +H + VS
Sbjct:  161 CEIDINECASRPCENNGTCVNGKDRYI-CECL-LGYTGTNCEVEVDECESDPCENGATCIDLVGLYTCDCV-KGFSGLNCEINIDECESAPCQNGGTCQDLVDSFKCDCGDSGYMGDLCEEDIPECASDPCQHGATC--EEGTKEYTCTC-WPGYEGQNCEVDIDECVDAPCENGGECFENSDPMQWTSDWTFSYATAAGYVCQCQPGYTGETCSVNIDECVSEPCHNGGQCEDRVNGYVCICADGYRGVECEVD-------------------IDECE------------------SAPCQNGGVCEDLVGDYECNCEKASRGLQAWGGRQCTVELLGCLNHQCQNGATCRPWLDGDKHRHTCLCAPGFYD----DLCSTATTFSFSQPGYFLLEVSVEERKKRSPETEHPLQVCLRFRTTLPDRLLF-FRGNSDHFLSLELVRGALRGWAESKEDGVSLQVTSTDLANDGEWHEVCVS 592          

HSP 2 Score: 67.3958 bits (163), Expect = 1.990e-10
Identity = 81/290 (27.93%), Postives = 115/290 (39.66%), Query Frame = 1
Query: 2272 ICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCE-KPKPCPVGYCLYGGKCRMVNGMPR--CNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCT-NKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKV 3111
            +C+  G  + G DCE     C   +C+    C+ + G     C   V E        C  D C+      L + +    C+C   G  G  C   I  C    C  N  C  + D  VC C  G+ G+ CE+ I  C    C NG  C+       C C   +QG +CE     C    C   G C  VNG  R  C C           +  +C    CENG  C  +  ++ C+C    ++G  C  N   C    C+NGG C+     F C+C  +GY G+ C++ +
Sbjct:    7 LCSRDGVRYMGKDCEELYDACVFAECEG---CVSELGTGNFTCPAEVDE--------CASDPCIGARTECLKEPDGF-LCLC-PDGLGGDDCTARITDCVDQPCLNNATCRRQLDGFVCECAPGYRGEHCEEDINECLSHPCQNGAICMDGINEYHCFCVPGYQGYNCEIDINECASRPCENNGTC--VNGKDRYICECLLGYTGTNCEVEVDECESDPCENGATCIDLVGLYTCDCVK-GFSGLNCEINIDECESAPCQNGGTCQDLVDSFKCDCGDSGYMGDLCEEDI 280          

HSP 3 Score: 62.7734 bits (151), Expect = 5.063e-9
Identity = 81/358 (22.63%), Postives = 130/358 (36.31%), Query Frame = 1
Query: 1612 LLVNSNSIILAYSLPPNEGVHTIEMTRGGILIQDNTWHRVIINLNKPKEILYIHIDDVESLTNEIKLKNSKKELAEMNFISLSLGGISDNSQYTQFYNLLRKKNPEVSKLFSGPDELKFIGCLGDILVINSSYSGNLIQKPNVNSFPKESLFCRACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCET----PKCPLDFCLNNGHCLLNQVNQLPY---CVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCE 2652
            LL+     ++   L     V  +  T G   + D  WH +++++  P++   + +  V+ + +     ++ + +  M F+S     ++    YT    L+R                  +G  G  L     +      +       +  L C         C    CQ+ G C ++      C C    + G  C+I    C   PC +G C+       C C   GF G  C+  +  C +  CQN   C+       C C +  Y G+ C+      KC    C++ G C        P+   C+C + G  G RC   I  C  N C   G CL R     C C  GF+G  CE
Sbjct: 1022 LLIGLLDGVVRAELHGENSVEPVVFT-GSQRVTDGLWHHLVVSMEHPEQDASLWVISVDGIMDG---SSAPEHIESMGFLSDVTSEVALAESYTGCLGLVR------------------VG--GTYLPFTDDFVAPQAARFRRRRGERARLGCVG----SSVCRPQPCQHGGTCEDLFH-HFHCACP-LGWEGLTCEIDTDECASGPCVHGNCRDKLGGFECECE-PGFGGATCDEDLDECKDSPCQNRATCVDGVNQYSCICARG-YSGKQCQWNHPPQKCADLECVSGGVC-----RDAPWGAECIC-APGLTGRRCEIEINECMSNPCLNGGTCLDRLSFFQCVCAAGFSGPYCE 1341          
BLAST of notch-1 vs. Ensembl Cavefish
Match: notch3 (neurogenic locus notch homolog protein 2 [Source:NCBI gene;Acc:103042072])

HSP 1 Score: 103.219 bits (256), Expect = 2.874e-21
Identity = 113/371 (30.46%), Postives = 160/371 (43.13%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINET-KIACDCKKTQFYGEFCDIKRPSCDPNPCKN-GICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLC--ETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRC--NKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGYCLY------GGKCRMVNGMPRCNCTQT------NYMGXXXXXXXXXXXXY--CENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            C E +  C  N C N   C +  +     C+C+   + G  C+I    C  NPCKN G C       +C+C G G++G +CE  I+ C  + C + G C        C C    + G  C  E  +C    C N G C  + VN    C C   GF G  C  N   C ++ C   G C+ + +   C C  GFTG+ C+  +  C    C+NGG C     S  C C K + G  C+      V +C +      GG+CR  +G   C+C         +  G  CE        Y  C  GG C    N   C C N  YTG  C ++V  C D  C NG  C  + G + C+C + GY G+ C+++++
Sbjct:  686 CAEVLTPCSPNPCSNHAVCTHTPDYFGYQCNCQPG-WQGHLCNIDVNECASNPCKNRGTCTNTLGGYVCSCRG-GYSGPNCETDINDCLPNPCMSGGSCTDGINTFYCTCLPG-FTGPRCAIEVDECQSAPCKNGGTCT-DYVNSY-TCTCKP-GFTGLHCETNAMDCTESSCFNGGTCVDKINGFSCTCRVGFTGEHCQYEVNECDSQPCLNGGVCQDGLESFRCSCPKGYTGSRCQV----RVDWCRHSNPCQNGGRCRPKDG--SCDCVGGWSGRYCDIPGVSCEMAAMQRGLYELCHRGGHCVNTGNTHYCKCPN-DYTGSYCESQVDHCEDKPCLNGATCRGYVGGYTCDC-MPGYEGQNCEREIN 1042          

HSP 2 Score: 85.5001 bits (210), Expect = 6.240e-16
Identity = 119/398 (29.90%), Postives = 154/398 (38.69%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYN-INETKIACDCKKTQFYGEFCDIKRPSCDPNPCKN-GICQIVGNNRICNCTGTGFTGFDCEIS--RCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCET--PKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRC----------------------NKPICPQNYCTKNGNCLVR-DDSAV----------------CYCDEGFTGDKC--EKPICSKDKCINGGKCVVVDRSPFCVCAKDFQGKSC-EKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKV--GCPDNYCKNGGACEIHRGKFG--CNCSLTGYGGEQCDQKVD 3114
            C+ ++ +C    CQN   C + I E    C      + G  C+I    C+ NPC N GIC+ + N   C C  TGFTG  C+I    C +  CQN   CI +    EC C +  +EG+LCE+    C  D C ++G C+    +    CV    G+ GYRC                      NK IC   + T   NC +  DD A                 C C  GFTG +C  E   CS + C NGG CV  +    C+C   F    C      C    C++G  CR      RC C               C    C+N G C    N F C C      G     +V   C  N C N   C      FG  CNC   G+ G  C+  V+
Sbjct:  345 CEIDINECLSMPCQNDATCLDRIGEFTCIC---MPGYTGTHCEIDIDECESNPCVNDGICRDLVNAFTCTCQ-TGFTGTMCQIDIDECASTPCQNGAKCIDRPNGYECRCAEG-FEGRLCESNIDNCQPDPC-HHGTCVDGIASYTCNCV---PGYTGYRCENQLNECHSNPCQNGGKCVDLVNKYICQCQHGTSGTNCEINYDDCASNPCEYGMCKDGINRYDCVCKPGFTGPQCNVELDECSSNPCRNGGTCVDDENGFHCLCPAGFHEPYCFSHVDECSSSPCVHGA-CREDPDGYRCECEPGWVGKNCDLDRNDCLPNPCQNAGTCIDQLNGFTCKCRQGFRGGGPTCAEVLTPCSPNPCSNHAVCTHTPDYFGYQCNCQ-PGWQGHLCNIDVN 731          

HSP 3 Score: 82.8037 bits (203), Expect = 3.870e-15
Identity = 107/367 (29.16%), Postives = 161/367 (43.87%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQI--VGNNRICNCTGTGFTGFDC--EISRCF--NHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCE------KPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXX-XXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCT-NKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            C EN+  C    C N   C++       C+C   +  G  C +   +C  NPC  G +C    +    IC C   GF G  C  ++  C    + C++ G C+   G  +C C +  Y G  CE    +C    C N+  CL +++ +   C+C   G+ G  C   I  C  N C  +G C    ++  C C  GFTG  C+  I  C+   C NG KC+       C CA+ F+G+ CE      +P PC  G C+ G      N +P        Y G +   +  +C    C+NGG C  + N +IC C + + +G  C  N   C  N C+  G C+    ++ C C   G+ G QC+ ++D
Sbjct:  228 CSENIDDCATAVCFNGATCHD-RVASFYCECPVGK-TGLLCHLDD-ACVSNPCNEGAVCDTNPLNGRAICTCP-AGFIGGACIQDMDECSIGANPCEHFGKCVNTVGSFQCQCGRG-YTGPRCEIDINECLSMPCQNDATCL-DRIGEF-TCIC-MPGYTGTHCEIDIDECESNPCVNDGICRDLVNAFTCTCQTGFTGTMCQIDIDECASTPCQNGAKCIDRPNGYECRCAEGFEGRLCESNIDNCQPDPCHHGTCVDGIASYTCNCVP-------GYTGYRCENQLNECHSNPCQNGGKCVDLVNKYICQCQHGT-SGTNCEINYDDCASNPCEY-GMCKDGINRYDCVCK-PGFTGPQCNVELD 576          

HSP 4 Score: 76.2554 bits (186), Expect = 4.115e-13
Identity = 101/340 (29.71%), Postives = 136/340 (40.00%), Query Frame = 1
Query: 2152 KIACDCKKTQFYGEFCDIKRPSCDPNPCKNGI-CQIVGNNRICNCTGTGFTGFDC--EISRCFN-HKCQNNGICILKQGIPECDCTKTVYEGQLCETPK--CPLDFCLNNGHCLLNQVNQLPY-CVCNSTGFYGYRC--NKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI----CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSC-EKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSI--INNVFICNCSNVSYTGERC---TNKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            +  C C++  F G+ C +   +C  +PC NG  C    N+  C+C   GF G +C  +I  C    KC N GICI   G   C+C  + Y G+ CE P   C    CLN G C  +Q     Y C C   GF G  C  N   CP + C   G C+   ++  C C   +TG  C + +       + C NGG C        CVC   + G  C E    C    C  G  C        C C      G  C     C    C  G +C    +N   IC C    + G  C    ++     N C++ G C    G F C C   GY G +C+  ++
Sbjct:   21 QFTCVCQRG-FRGQNCSLID-ACATSPCANGARCTNWNNHYNCSCP-PGFQGKNCRNDIDECRKPGKCLNGGICINTHGSFRCECV-SGYSGRTCEVPTQPCAPSQCLNGGTC--HQTGDHTYECAC-LPGFGGTNCEVNVDDCPGHKCMNGGTCVDGVNTYNCQCPPEWTGQYCAEDVNECLMQPNACHNGGTCFNTIGGHTCVCVNGWTGDDCSENIDDCATAVCFNGATCHDRVASFYCECP-VGKTGLLCHLDDACVSNPCNEGAVCDTNPLNGRAICTCP-AGFIGGACIQDMDECSIGANPCEHFGKCVNTVGSFQCQCG-RGYTGPRCEIDIN 350          

HSP 5 Score: 71.633 bits (174), Expect = 9.311e-12
Identity = 103/366 (28.14%), Postives = 145/366 (39.62%), Query Frame = 1
Query: 2071 RACQENVKKCPK-NYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRI-CNCTGTGFTGFDCEIS--RCFNHKCQNNGICILKQGIPECDCTKTVYEGQLC--ETPKCPL--DFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCE-KPICSKDKCINGGKCVV--VDRSPFCVCAKDFQGKSC-EKPKPCPVGY--CLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            + C+ ++ +C K   C N G C N + +   C+C  + + G  C++    C P+ C NG  C   G++   C C   GF G +CE++   C  HKC N G C+       C C    + GQ C  +  +C +  + C N G C          CV    G+ G  C++ I  C    C     C  R  S  C C  G TG  C     C  + C  G  C    ++    C C   F G +C +    C +G   C + GKC    G  +C C +     +      +C    C+N   C      F C C    YTG  C   +  C  N C N G C      F C C  TG+ G  C   +D
Sbjct:   70 KNCRNDIDECRKPGKCLNGGICINTHGS-FRCECV-SGYSGRTCEVPTQPCAPSQCLNGGTCHQTGDHTYECACL-PGFGGTNCEVNVDDCPGHKCMNGGTCVDGVNTYNCQCPPE-WTGQYCAEDVNECLMQPNACHNGGTCFNTIGGHTCVCV---NGWTGDDCSENIDDCATAVCFNGATCHDRVASFYCECPVGKTGLLCHLDDACVSNPCNEGAVCDTNPLNGRAICTCPAGFIGGACIQDMDECSIGANPCEHFGKCVNTVGSFQCQCGRGYTGPRCEIDINECLSMPCQNDATCLDRIGEFTCICM-PGYTGTHCEIDIDECESNPCVNDGICRDLVNAFTCTCQ-TGFTGTMCQIDID 426          

HSP 6 Score: 67.3958 bits (163), Expect = 1.841e-10
Identity = 77/262 (29.39%), Postives = 100/262 (38.17%), Query Frame = 1
Query: 2113 CQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCE-------TPKCPLDF--CLNNGHCLLNQVNQLPYCVCN-STGFYGYRCNKPI--CPQNYCTKNG--NCLVRDDSAVCYCDEGFTGDKCEKPI----------------------------CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEK 2763
            C   G C N   T   C C    + G +C+ +   C+  PC NG  C+       C+C   G+ G +CE  I+ C +H CQN G CI   G   C C      G LCE       TP  P     C NNG C    V+++    CN   G+ G RC   I  C  N C      +C+   +  +C C  GFTG  C+                               C +  C NGG C V  R   C C + F G  C+ 
Sbjct:  973 CHRGGHCVNTGNTHY-CKCPN-DYTGSYCESQVDHCEDKPCLNGATCRGYVGGYTCDCM-PGYEGQNCEREINECRSHPCQNGGTCIDLVGHYICSCPPGTM-GVLCEINEDDCATPTRPRGTPKCQNNGTC----VDRVGGYRCNCPPGYTGDRCEGDINECHSNPCNAANSLDCIQLPNDYLCVCKPGFTGRGCQNRFGVCESQPCKNGGACSGGYTGTNCERSMSCRELSCYNGGSCTVTSRGARCSCQQGFAGPQCQH 1226          

HSP 7 Score: 61.2326 bits (147), Expect = 1.506e-8
Identity = 98/364 (26.92%), Postives = 134/364 (36.81%), Query Frame = 1
Query: 2071 RACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGICQIVG-NNRICNCTGTGFTGFDC--EISRCFNH--KCQNNGICILKQGIPECDCTKTVYEGQLCET--PKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCN-KPICPQNYCTKNGNCLVR--DDSAVCYCDEGFTGDKCEKPI--CS--KDKCINGGKCVVVDRSPFCVCAKDFQGKSCE-KPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            R C+   + C  + C N G C+   +    C C    F G  C++    C  + C NG   + G N   C C    +TG  C  +++ C      C N G C    G   C C    + G  C      C    C N   C  ++V    YC C   G  G  C+    C  N C +   C     +  A+C C  GF G  C + +  CS   + C + GKCV    S  C C + + G  CE     C    C     C    G   C C              +C    C N GIC  + N F C C    +TG  C   +  C    C+NG  C      + C C+  G+ G  C+  +D
Sbjct:  109 RTCEVPTQPCAPSQCLNGGTCHQTGDHTYECACLPG-FGGTNCEVNVDDCPGHKCMNGGTCVDGVNTYNCQCPPE-WTGQYCAEDVNECLMQPNACHNGGTCFNTIGGHTCVCVNG-WTGDDCSENIDDCATAVCFNGATC-HDRVASF-YCEC-PVGKTGLLCHLDDACVSNPCNEGAVCDTNPLNGRAICTCPAGFIGGACIQDMDECSIGANPCEHFGKCVNTVGSFQCQCGRGYTGPRCEIDINECLSMPCQNDATCLDRIGEFTCICMPGYTGTHCEIDIDECESNPCVNDGICRDLVNAFTCTC-QTGFTGTMCQIDIDECASTPCQNGAKCIDRPNGYECRCA-EGFEGRLCESNID 464          

HSP 8 Score: 59.3066 bits (142), Expect = 5.271e-8
Identity = 78/268 (29.10%), Postives = 100/268 (37.31%), Query Frame = 1
Query: 2341 CQNNGIC--ILKQGIPECDCT-KTVYEGQLCE-TPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICPQNYCTKNGNCLV------RDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVV-DRSPFCVCAKDFQGKSCE-KPKPCPVGYCLYGGKCRMVNGMPRCNCT----QTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKV-GCPDNYCKNGGACEIHRGKFGCNCSLTGYG 3087
            C N   C   +  G+P+  C  +  + GQ C     C    C N   C     N    C C   GF G  C   I   + C K G CL          S  C C  G++G  CE P   C+  +C+NGG C    D +  C C   F G +CE     CP   C+ GG C  V+G+   NC      T     +           C NGG C        C C N  +TG+ C+  +  C    C NG  C      F C C +   G
Sbjct:    5 CLNGAACKSQVANGVPQFTCVCQRGFRGQNCSLIDACATSPCANGARC--TNWNNHYNCSC-PPGFQGKNCRNDI---DECRKPGKCLNGGICINTHGSFRCECVSGYSGRTCEVPTQPCAPSQCLNGGTCHQTGDHTYECACLPGFGGTNCEVNVDDCPGHKCMNGGTC--VDGVNTYNCQCPPEWTGQYCAEDVNECLMQPNACHNGGTCFNTIGGHTCVCVN-GWTGDDCSENIDDCATAVCFNGATCHDRVASFYCECPVGKTG 263          
BLAST of notch-1 vs. Ensembl Sea Lamprey
Match: JAG1 (jagged canonical Notch ligand 1 [Source:HGNC Symbol;Acc:HGNC:6188])

HSP 1 Score: 88.1965 bits (217), Expect = 1.669e-17
Identity = 105/354 (29.66%), Postives = 156/354 (44.07%), Query Frame = 1
Query: 2071 RACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGI--CQIVGNNRICNCTGTGFTGFDCEI--SRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CS-KDKCINGGKCVVVDRSPFCVCAKDFQGKSCE-KPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXX--YCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGE 3093
            R C+  V +C  + C N G+C +  ++   C C    F G+ C++    C PNPC+NG     +   +  C+C+   F G +C +    C    CQ    C +   +P    + T   G    T       C  NG C L+Q      C+CNS GF G  C++ +  C +  C   G CL   +S  C C +G+ G+ CE  +  CS  + C+NGG C  +     C C   ++GK+C  K   C    C  GG+C  V    RC+C  T + G  C   +        C+NG  C I  + + C C +  + G  CT  +  C  + C NGG C      + C C+  G+ GE
Sbjct:  347 RRCETEVNECASHPCLNGGQCRDAIDSYY-CVCMDG-FAGDSCELDVDLCVPNPCQNGARCVNLPNGDYFCHCS-ENFEGTNCTLLKDHCLTSPCQVIDSCTV--AVP----SNTSESGVAHVTST----VCGPNGRC-LSQAGGNFTCMCNS-GFRGSFCHENVNDCAEGACHNGGTCLDGINSFQCMCPDGWDGEFCENDVDDCSNHNPCLNGGTCHDLVNDFSCECKNGWKGKTCHSKISHCDEATCNNGGECFDVGDTFRCSCP-TGWEGPTCNIAQSIACMPNPCQNGATCVISGDSYKCICQS-GWEGANCTQDINDCSSHPCYNGGTCVDGTNWYRCECA-AGFAGE 682          

HSP 2 Score: 61.6178 bits (148), Expect = 1.763e-9
Identity = 105/377 (27.85%), Postives = 146/377 (38.73%), Query Frame = 1
Query: 2113 CQNKGRCYNINETKIACDCKKTQFYGEFCDIK--RPSCDPNPCKNGICQIVGNNRICNCTGTGFTGFDC--EISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLC--ETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICP-QNYCTKNGNC--LVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCE-KPKPCPVGYCLYGGKC-RMVNGMPRCNCTQTNYMG----------------------------XXXXXXXXXXXXYCENGGIC-SIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            C+N G C N       CDC+K  ++G  C+I   +     N C NG   +   +        G+TG +C  +I  C +  C N G C+       C C    + G  C  +T +C  + C++   C    +    YC C   G+ G  C+  +   +  C   G C  LV D S  C C  G+TG +CE  +  C+   C+NGG+C     S +CVC   F G SCE     C    C  G +C  + NG   C+C++ N+ G                                         C   G C S     F C C N  + G  C   V  C +  C NGG C      F C C   G+ GE C+  VD
Sbjct:  169 CRNGGSCSNAQPDSYKCDCQKG-YHGVNCEIDYVQHITLNNTCANGGSSVGSPSGYKCLCAPGWTGANCTEDIDECASSPCGNGGTCLNLVNGFRCTCPPQ-WTGHTCLVDTDECDDNPCVHARSC--KNLFGGYYCGC-LPGWTGQNCDIDVNDCEGKCLNGGTCKDLVNDYS--CECKPGYTGRRCETEVNECASHPCLNGGQCRDAIDSYYCVCMDGFAGDSCELDVDLCVPNPCQNGARCVNLPNGDYFCHCSE-NFEGTNCTLLKDHCLTSPCQVIDSCTVAVPSNTSESGVAHVTSTVCGPNGRCLSQAGGNFTCMC-NSGFRGSFCHENVNDCAEGACHNGGTCLDGINSFQCMCP-DGWDGEFCENDVD 535          

HSP 3 Score: 55.4546 bits (132), Expect = 1.334e-7
Identity = 69/270 (25.56%), Postives = 111/270 (41.11%), Query Frame = 1
Query: 2071 RACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRP-SCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDC--EISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICPQNYCTKNGN-----CLVRDDSAVCYCDEGFTGDKCEKPICSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCE--KPKPCPVGYCLYGGKCRMVNGMPRCNCTQ 2847
            + C   +  C +  C N G C+++ +T   C C  T + G  C+I +  +C PNPC+NG  C I G++  C C  +G+ G +C  +I+ C +H C N G C+       C+C        + E    P   C  +  C ++++N    C+C   G  G  C+  + P   C  +G         +++  +C+C  G     C K  C    C+        +R           G SC   + + C  G C   G+C      P   C Q
Sbjct:  567 KTCHSKISHCDEATCNNGGECFDVGDT-FRCSC-PTGWEGPTCNIAQSIACMPNPCQNGATCVISGDSYKCICQ-SGWEGANCTQDINDCSSHPCYNGGTCVDGTNWYRCECAAGFAGEDINECQSMP---CAKDATC-IDEINGY-RCMC-PLGRAGRHCHDEV-PTQPCVASGRNHSHGSSWKEECNMCHCSNGNI--NCTKVWCGNKLCLLSPAAASAERDGC------PAGLSCHAMRHESCLAGSCFRQGECLPQTSPPASLCQQ 818          
BLAST of notch-1 vs. Ensembl Sea Lamprey
Match: lrp1ab (low density lipoprotein receptor-related protein 1Ab [Source:ZFIN;Acc:ZDB-GENE-030131-7126])

HSP 1 Score: 79.7221 bits (195), Expect = 7.516e-15
Identity = 64/199 (32.16%), Postives = 95/199 (47.74%), Query Frame = 1
Query: 2341 CQNNGICIL-KQGIPECDCTKTVYEGQLCETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICPQNYCTKNGNCLVR-DDSAVCYCDEGFTGDKCEKPICSKDKCINGGKCVVV-DRSPFCVCAKDFQGKSCEKPK--PCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGIC 2922
            C N G C L ++G+ +C C +  + G+ CE  +C  ++C N G C+ +  + +P C C +  F G +C + +C   YC   G C V   +  VC C + + GD+C+  +C  + C+NGG C    D SP C C   F G  C+  +   CP G C  G       G  RCNCT                 ++C NGG+C
Sbjct: 4172 CLNGGSCFLNERGLAKCKC-QPRFSGERCELDQCK-EYCQNGGTCMASP-SGMPTCRCPNR-FTGAQCERKVC-DGYCLNGGACSVNAGNQPVCRCTDAYKGDRCQSTLCD-NYCMNGGVCSFAKDGSPLCACHPRFLGTRCDTDRCGHCPGGQCELGPGA----GDVRCNCT---------GPACSRCLEFCYNGGLC 4351          

HSP 2 Score: 74.7146 bits (182), Expect = 2.346e-13
Identity = 94/332 (28.31%), Postives = 133/332 (40.06%), Query Frame = 1
Query: 2428 TPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICPQNYCTKNGNCLVRDDS-AVCYCDEGFTGDKCEKPICSKDKCINGGKCVVVDRS-PFCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRMVNG-MPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVF-ICNCSNVSYTGERC-TNKVG-CPDNYCKNGGACEI--HRGKFGCNC---------------------SLTGYGGEQCDQKVDGVMCDYKEPGYAITAFKPPMVSSGIVTSMGFQTFVKTGTLFCYE---TADDKYWLIKLVNGRLVADINGISFNM 3327
            T  CP  + L NG CL     ++P       G     C  P      C   G+C + +   A C C   F+G++CE   C K+ C NGG C+      P C C   F G  CE+ K C  GYCL GG C +  G  P C CT   Y G +C+        YC NGG+CS   +   +C C +  + G RC T++ G CP      GG CE+    G   CNC                     S+ G    QC    +G  C+   P  + +  +   +S  +   +     V     FCY         +   ++ NG +  +I   ++NM
Sbjct: 4136 TCSCPNGWALVNGTCL-----EVPTPTSQPDGSTPGPCTLP------CLNGGSCFLNERGLAKCKCQPRFSGERCELDQC-KEYCQNGGTCMASPSGMPTCRCPNRFTGAQCER-KVCD-GYCLNGGACSVNAGNQPVCRCTDA-YKGDRCQSTLCDN--YCMNGGVCSFAKDGSPLCAC-HPRFLGTRCDTDRCGHCP------GGQCELGPGAGDVRCNCTGPACSRCLEFCYNGGLCFWDSVAGRPACQCQPGWEGSQCERNSPNRSTSPDEGKTLSVVVPLVLLALIIVSVVAFFCYRRRVKGAKGFQHQRMTNGAMNVEIGNPTYNM 4443          

HSP 3 Score: 53.5286 bits (127), Expect = 6.235e-7
Identity = 52/178 (29.21%), Postives = 69/178 (38.76%), Query Frame = 1
Query: 2104 KNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGICQI-VGNNRICNCTGTGFTGFDCEISRCFNHKCQNNGIC-ILKQGIPECDCTKTVYEGQLCETPKCP----------------------------LDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNK 2547
            K YCQN G C         C C   +F G  C+  R  CD      G C +  GN  +C CT   + G  C+ + C N+ C N G+C   K G P C C    + G  C+T +C                             L+FC N G C  + V   P C C   G+ G +C +
Sbjct: 4205 KEYCQNGGTCMASPSGMPTCRCPN-RFTGAQCE--RKVCDGYCLNGGACSVNAGNQPVCRCT-DAYKGDRCQSTLCDNY-CMNGGVCSFAKDGSPLCAC-HPRFLGTRCDTDRCGHCPGGQCELGPGAGDVRCNCTGPACSRCLEFCYNGGLCFWDSVAGRPACQCQP-GWEGSQCER 4375          
BLAST of notch-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002014.1 (pep scaffold:Pmarinus_7.0:GL482490:2146:12219:-1 gene:ENSPMAG00000001825.1 transcript:ENSPMAT00000002014.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 73.559 bits (179), Expect = 1.390e-14
Identity = 65/196 (33.16%), Postives = 87/196 (44.39%), Query Frame = 1
Query: 2086 NVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGF--DCEISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCE 2652
            +V +C  N CQN GRC +       CDC +  F G+ C+     C  +PC+NG  C     +  C+C   G+TG   D +I  C +  CQN G C+   G   C C    Y G LC++   +C    CLN G C          C   + GF G RC   +  C  + C   G C     +  C C  GFTG +CE
Sbjct:   11 DVDECSPNPCQNGGRCID-GAASYTCDCAQ-GFTGKRCETDIDECTSDPCQNGGQCVNGAGSFTCSCL-AGYTGTLCDSDIDECTSDPCQNGGQCVNGAGSFTCSCLAG-YTGTLCDSDVNECASSPCLNGGRCRDGVAAFTCEC---APGFTGTRCETDVNECASSPCLNGGRCRDGVAAFTCECAPGFTGTRCE 199          

HSP 2 Score: 65.855 bits (159), Expect = 5.080e-12
Identity = 62/187 (33.16%), Postives = 79/187 (42.25%), Query Frame = 1
Query: 2554 CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKP-KPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCD 3102
            C  N C   G C+    S  C C +GFTG +CE  I  C+ D C NGG+CV    S  C C   + G  C+     C    C  GG+C    G   C+C              +C    C NGG C      F C C+   +TG RC   V  C  + C NGG C      F C C+  G+ G +C+
Sbjct:   15 CSPNPCQNGGRCIDGAASYTCDCAQGFTGKRCETDIDECTSDPCQNGGQCVNGAGSFTCSCLAGYTGTLCDSDIDECTSDPCQNGGQCVNGAGSFTCSCLAGYTGTLCDSDVNECASSPCLNGGRCRDGVAAFTCECA-PGFTGTRCETDVNECASSPCLNGGRCRDGVAAFTCECA-PGFTGTRCE 199          

HSP 3 Score: 54.299 bits (129), Expect = 4.955e-8
Identity = 51/153 (33.33%), Postives = 67/153 (43.79%), Query Frame = 1
Query: 2662 CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKP-KPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            CS + C NGG+C+    S  C CA+ F GK CE     C    C  GG+C    G   C+C              +C    C+NGG C      F C+C    YTG  C + V  C  + C NGG C      F C C+  G+ G +C+  V+
Sbjct:   15 CSPNPCQNGGRCIDGAASYTCDCAQGFTGKRCETDIDECTSDPCQNGGQCVNGAGSFTCSCLAGYTGTLCDSDIDECTSDPCQNGGQCVNGAGSFTCSCL-AGYTGTLCDSDVNECASSPCLNGGRCRDGVAAFTCECA-PGFTGTRCETDVN 165          

HSP 4 Score: 50.8322 bits (120), Expect = 7.412e-7
Identity = 52/174 (29.89%), Postives = 74/174 (42.53%), Query Frame = 1
Query: 2071 RACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKN-GICQIVGNNRICNCTGTGFTGF--DCEISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICPQNYCTK 2577
            + C+ ++ +C  + CQN G+C N       C C    + G  CD     C  +PC+N G C     +  C+C   G+TG   D +++ C +  C N G C        C+C    + G  CET   +C    CLN G C          C   + GF G RC   +   N CTK
Sbjct:   44 KRCETDIDECTSDPCQNGGQCVN-GAGSFTCSCLA-GYTGTLCDSDIDECTSDPCQNGGQCVNGAGSFTCSCL-AGYTGTLCDSDVNECASSPCLNGGRCRDGVAAFTCECAPG-FTGTRCETDVNECASSPCLNGGRCRDGVAAFTCEC---APGFTGTRCETVL---NPCTK 207          
BLAST of notch-1 vs. Ensembl Sea Lamprey
Match: VWDE (von Willebrand factor D and EGF domains [Source:HGNC Symbol;Acc:HGNC:21897])

HSP 1 Score: 74.3294 bits (181), Expect = 2.933e-13
Identity = 87/290 (30.00%), Postives = 119/290 (41.03%), Query Frame = 1
Query: 2275 CNCTGTGFTGFDCEISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPICSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKP---KPCP-VGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVDGVMCDY 3132
            C C   G+TG++C I+ C    C+N G C+       C+C    Y+G +CE  +C    C N G C+   +   PY      G+ G RC   +C   +C   G C+  D   VC C  G+ G  C   +CS   C+NGG CV   R   C+C   F G  C       PC   G+C+    C    G     C ++              E  C N G C   N   +C+C +  + G+RC   V      CKNGG C    G   C+C   G+ G  C   V    C +
Sbjct: 1324 CRCK-PGYTGYNCLIAVC-RPDCKNQGKCVRPD---VCEC-PLGYKGPICEEVEC-TPTCQNAGACIARNLCSCPY------GYLGPRCETMVC-NRHCENGGECVSPD---VCRCSPGWDGPTCGSAVCSP-VCLNGGACV---RPGVCLCPHGFFGAQCHNAICSPPCKNGGHCMRNNICSKGEGYTGRRCQKS------------VCEPTCMNSGKCVGPN---VCSCPS-GFKGKRCNRPVCL--QKCKNGGECI---GPNSCHCP-EGWEGMHCQNPVCQQTCKF 1570          

HSP 2 Score: 69.3218 bits (168), Expect = 9.038e-12
Identity = 76/264 (28.79%), Postives = 110/264 (41.67%), Query Frame = 1
Query: 2113 CQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGICQIVGNNRICNCTGTGFTGFDCEISRCFNHKCQNNGICILKQ--------GIPECD---CTKTVYEGQLCETPK---CPLDF-------------CLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPICSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRMVNG 2823
            C+N+G+C   +     C+C    + G  C+     C P  C+N    I  N  +C+C   G+ G  CE   C  H C+N G C+             P C    C+     G  C  P    CP  F             C N GHC+ N +           G+ G RC K +C +  C  +G C+      VC C  GF G +C +P+C + KC NGG+C+  +    C C + ++G  C+ P  C    C +GG+C   N 
Sbjct: 1344 CKNQGKCVRPD----VCECP-LGYKGPICE--EVECTPT-CQNAGACIARN--LCSCP-YGYLGPRCETMVCNRH-CENGGECVSPDVCRCSPGWDGPTCGSAVCSPVCLNGGACVRPGVCLCPHGFFGAQCHNAICSPPCKNGGHCMRNNI------CSKGEGYTGRRCQKSVC-EPTCMNSGKCV---GPNVCSCPSGFKGKRCNRPVCLQ-KCKNGGECIGPNS---CHCPEGWEGMHCQNPV-C-QQTCKFGGRCTAPNA 1579          
BLAST of notch-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002643.1 (pep scaffold:Pmarinus_7.0:GL478752:33855:40482:1 gene:ENSPMAG00000002413.1 transcript:ENSPMAT00000002643.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 71.2478 bits (173), Expect = 4.979e-13
Identity = 73/238 (30.67%), Postives = 101/238 (42.44%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGICQIVGNNRICNCTGTGFTGFDCEI--SRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKP 2766
            C+ +V  C    C N   C +       C C    F G  C+I    C   PC +G     G +R       GF G  C++  + C +  C N   C+   G  EC C +  Y G +CET   +C    C N G C ++ V+    C C  TG+ G  C   I  C  N C  N  C+    +  C C  GF GD CE+ +  C  + C+NGG+C+ + +        DF GK  E P
Sbjct:   33 CEASVGGCASGPCLNDAVCVD-EPGGYKCYCVP-GFQGRHCEIDINECASEPCLHGGTCTNGRDRYSCACPDGFAGERCQLDTNECASQPCHNGATCVDLDGKFECVCPRG-YTGAMCETEVDECESGPCQNGGVC-IDLVDSY-TCDCLETGYEGKDCELEILECASNPCRHNSTCIEGILNFTCICWPGFAGDACEEDVNECGDEPCMNGGQCIELSK-------PDFYGKLSELP 258          

HSP 2 Score: 68.5514 bits (166), Expect = 3.102e-12
Identity = 75/255 (29.41%), Postives = 103/255 (40.39%), Query Frame = 1
Query: 2071 RACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCL--------------------VRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQG 2748
            R C+ ++ +C    C + G C N    + +C C    F GE C +    C   PC NG  C  +     C C   G+TG  CE  +  C +  CQN G+CI       CDC +T YEG+ CE    +C  + C +N  C+   +N    C+C   GF G  C + +  C    C   G C+                           C C  G TG+ C   +  C    C+NGG C+    S  C CA  F G
Sbjct:   69 RHCEIDINECASEPCLHGGTCTN-GRDRYSCACPD-GFAGERCQLDTNECASQPCHNGATCVDLDGKFECVCP-RGYTGAMCETEVDECESGPCQNGGVCIDLVDSYTCDCLETGYEGKDCELEILECASNPCRHNSTCIEGILNFT--CIC-WPGFAGDACEEDVNECGDEPCMNGGQCIELSKPDFYGKLSELPGTFHYANASGFTCRCLPGTTGENCSVNLDECESQPCLNGGSCIDNIGSFSCECAPGFTG 317          

HSP 3 Score: 66.2402 bits (160), Expect = 1.869e-11
Identity = 59/191 (30.89%), Postives = 79/191 (41.36%), Query Frame = 1
Query: 2554 CPQNYCTKNGNCLVRDDSAV-CYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCE-KPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKV 3111
            C    C   G CL   D    C C  G++GD CE  +  C+   C+N   CV       C C   FQG+ CE     C    CL+GG C        C C       +      +C  + C NG  C  ++  F C C    YTG  C  +V  C    C+NGG C      + C+C  TGY G+ C+ ++
Sbjct:    1 CASGPCLHGGTCLPAADGGFSCRCAPGYSGDNCEASVGGCASGPCLNDAVCVDEPGGYKCYCVPGFQGRHCEIDINECASEPCLHGGTCTNGRDRYSCACPDGFAGERCQLDTNECASQPCHNGATCVDLDGKFECVCPR-GYTGAMCETEVDECESGPCQNGGVCIDLVDSYTCDCLETGYEGKDCELEI 190          

HSP 4 Score: 51.6026 bits (122), Expect = 9.003e-7
Identity = 91/338 (26.92%), Postives = 133/338 (39.35%), Query Frame = 1
Query: 2098 CPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKN-GICQIVGNNRICNCTGTGFTGFDCEI--SRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCE--TPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDE-GFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKP-KPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIIN-NVFICNCSNVSYTGERCT-NKVGCPDNYCKNGGACEIHRGKFGCNCS 3072
            C    C + G C    +   +C C    + G+ C+     C   PC N  +C        C C   GF G  CEI  + C +  C + G C   +    C C    + G+ C+  T +C    C N   C+   ++    CVC   G+ G  C   +  C    C   G C+   DS  C C E G+ G  CE  I  C+ + C +   C+    +  C+C   F G +CE+    C    C+ GG+C  +        ++ ++ GK             E  G     N + F C C     TGE C+ N   C    C NGG+C  + G F C C+
Sbjct:    1 CASGPCLHGGTCLPAADGGFSCRCAP-GYSGDNCEASVGGCASGPCLNDAVCVDEPGGYKCYCV-PGFQGRHCEIDINECASEPCLHGGTCTNGRDRYSCACPDG-FAGERCQLDTNECASQPCHNGATCV--DLDGKFECVC-PRGYTGAMCETEVDECESGPCQNGGVCIDLVDSYTCDCLETGYEGKDCELEILECASNPCRHNSTCIEGILNFTCICWPGFAGDACEEDVNECGDEPCMNGGQCIEL--------SKPDFYGKLS-----------ELPGTFHYANASGFTCRCL-PGTTGENCSVNLDECESQPCLNGGSCIDNIGSFSCECA 312          
BLAST of notch-1 vs. Ensembl Yeast
Match: TUP1 (General repressor of transcription; forms complex with Cyc8p, involved in the establishment of repressive chromatin structure through interactions with histones H3 and H4, appears to enhance expression of some genes [Source:SGD;Acc:S000000680])

HSP 1 Score: 66.6254 bits (161), Expect = 3.252e-11
Identity = 50/179 (27.93%), Postives = 86/179 (48.04%), Query Frame = 1
Query: 5356 TKNGQFLIAG-----FQTFDNSTSYMVFDMTMQSRKNGVFKINANTNCTDFINNNEAVTGTESGELIIWDLNTVQAVRRILISPNFVDNSESRNPHKDSLTCVTVS-NDGSLLATTGLDATVKVWNMEDEKLLYNLNK-------HKDEIQSLVWSNDNEMLVSGSLDGSIRIWNVTNG 5853
            + +G+FL  G      + +D     +V  M +Q  +  ++ ++       F + ++ V+G+    + IWDL T Q    + I              +D +T V VS  DG  +A   LD  V+VW+ E   L+  L+        HKD + S+V++ D + +VSGSLD S+++WN+ N 
Sbjct:  452 SPDGKFLATGAEDRLIRIWDIENRKIV--MILQGHEQDIYSLDY------FPSGDKLVSGSGDRTVRIWDLRTGQCSLTLSI--------------EDGVTTVAVSPGDGKYIAAGSLDRAVRVWDSETGFLVERLDSENESGTGHKDSVYSVVFTRDGQSVVSGSLDRSVKLWNLQNA 608          

HSP 2 Score: 59.3066 bits (142), Expect = 4.792e-9
Identity = 33/92 (35.87%), Postives = 52/92 (56.52%), Query Frame = 1
Query: 5614 SRNPHKD-SLTCVTVSNDGSLLATTGLDATVKVWNMEDEKLLYNLNKHKDEIQSLVWSNDNEMLVSGSLDGSIRIWNVTNGQEMCGFNSNIE 5886
            S +P  D  +  V  S DG  LAT   D  +++W++E+ K++  L  H+ +I SL +    + LVSGS D ++RIW++  GQ  C    +IE
Sbjct:  437 SSSPSSDLYIRSVCFSPDGKFLATGAEDRLIRIWDIENRKIVMILQGHEQDIYSLDYFPSGDKLVSGSGDRTVRIWDLRTGQ--CSLTLSIE 526          
BLAST of notch-1 vs. Ensembl Yeast
Match: CDC4 (F-box protein required for both the G1/S and G2/M phase transitions; modular substrate specificity factor which associates with core SCF (Cdc53p, Skp1p and Hrt1p/Rbx1p) to form the SCFCdc4 complex; SCFCdc4 acts as a ubiquitin-protein ligase directing ubiquitination of cyclin-dependent kinase (CDK) phosphorylated substrates, such as: Sic1p, Far1p, Cdc6p, Clb6p, and Cln3p [Source:SGD;Acc:S000001885])

HSP 1 Score: 57.3806 bits (137), Expect = 2.382e-8
Identity = 66/259 (25.48%), Postives = 114/259 (44.02%), Query Frame = 1
Query: 5122 FSLKLLMMWKFPDGQIIDSGYEYMCTTCCVSADGECVILADDMKDSSITILNLTNQQTRKLVYKAGLVNGDGIQLLKQTKNGQFLIAGFQTFDNSTSYMVFDMTMQSRKNG----VFK-INANTNCTDFI---NNNEAVTGTESGELIIWDLNTVQAVRRILISPNF--VDNSESRNPH-----KDSLTCV-TVSNDGSLLATTGLDATVKVWNMEDEKLLYNLNKHKDEIQSLVWSNDNEMLVSGSLDGSIRIWNVTN 5850
            F LK     KF   +    G+     TC    D   +  ADD       ++ + +   +K + +    +G G+  LK   +G  L++G        +  V+D+     K G    VFK  N+   C D +   N    VTG+    L +W L    +V       ++  V ++   NP+     +  +  V TVS  G+++ +   D T+ VW++   K LY L+ H D I S ++ ++ +  +S S+D +IRIW++ N
Sbjct:  360 FILKNWYNPKFVPQRTTLRGHMTSVITCLQFEDNYVITGADD------KMIRVYDSINKKFLLQLSGHDG-GVWALKYA-HGGILVSG----STDRTVRVWDI-----KKGCCTHVFKGHNSTVRCLDIVEYKNIKYIVTGSRDNTLHVWKLPKESSVPDHGEEHDYPLVFHTPEENPYFVGVLRGHMASVRTVSGHGNIVVSGSYDNTLIVWDVAQMKCLYILSGHTDRIYSTIYDHERKRCISASMDTTIRIWDLEN 601          
BLAST of notch-1 vs. Ensembl Yeast
Match: RSA4 (WD-repeat protein involved in ribosome biogenesis; may interact with ribosomes; required for maturation and efficient intra-nuclear transport or pre-60S ribosomal subunits, localizes to the nucleolus [Source:SGD;Acc:S000000668])

HSP 1 Score: 55.0694 bits (131), Expect = 9.375e-8
Identity = 27/71 (38.03%), Postives = 41/71 (57.75%), Query Frame = 1
Query: 5626 HKDSLTCVTVSNDGSLLATTGLDATVKVWNMEDEKLLYNLNKHKDEIQSLVWSNDNEMLVSGSLDGSIRIW 5838
            H  S+  V  S+D  LL +   D T+KVW++   KL  +L  HKDE+ ++ WS D + + SG  D  +R+W
Sbjct:  443 HVASVYQVAWSSDCRLLVSCSKDTTLKVWDVRTRKLSVDLPGHKDEVYTVDWSVDGKRVCSGGKDKMVRLW 513          

HSP 2 Score: 50.0618 bits (118), Expect = 3.308e-6
Identity = 22/78 (28.21%), Postives = 43/78 (55.13%), Query Frame = 1
Query: 5626 HKDSLTCVTVSNDGSLLATTGL-DATVKVWNMEDEKLLYNLNKHKDEIQSLVWSNDNEMLVSGSLDGSIRIWNVTNGQ 5856
            H  ++ C   +   S    TG  D T ++W+ + +  ++ L  H + +  + WS D E++ +GS+D +IR+W+  +GQ
Sbjct:  142 HGSTILCSAFAPHTSSRMVTGAGDNTARIWDCDTQTPMHTLKGHYNWVLCVSWSPDGEVIATGSMDNTIRLWDPKSGQ 219          

HSP 3 Score: 50.0618 bits (118), Expect = 3.513e-6
Identity = 21/73 (28.77%), Postives = 39/73 (53.42%), Query Frame = 1
Query: 5626 HKDSLTCVTVSNDGSLLATTGLDATVKVWNMEDEKLLYNLNKHKDEIQSLVWSNDNEMLVSGSLDGSIRIWNV 5844
            H+  +  V  S DG  + +   D ++K+W+  D K +     H   +  + WS+D  +LVS S D ++++W+V
Sbjct:  401 HQKLVNHVAFSPDGRYIVSASFDNSIKLWDGRDGKFISTFRGHVASVYQVAWSSDCRLLVSCSKDTTLKVWDV 473          

HSP 4 Score: 49.2914 bits (116), Expect = 6.023e-6
Identity = 41/166 (24.70%), Postives = 71/166 (42.77%), Query Frame = 1
Query: 5407 TSYMVFDMTMQSRKNGVFKINANTN-CTDFINNNEA--VTGTESGELIIWDLNTVQAVRRILISPNFVDNSESRNPHKDSLTCVTVSNDGSLLATTGLDATVKVWNMEDEKLLYN-LNKHKDEIQSLVW-------SNDNEMLVSGSLDGSIRIWNVTNGQEMCGF 5871
            T   VF +   +R +     + +T  C+ F  +  +  VTG       IWD +T   +  +               H + + CV+ S DG ++AT  +D T+++W+ +  + L + L  H   I SL W             L S S DG+I+IW+  +   +C +
Sbjct:  122 TPRAVFKVKPVTRSSSAIAGHGSTILCSAFAPHTSSRMVTGAGDNTARIWDCDTQTPMHTL-------------KGHYNWVLCVSWSPDGEVIATGSMDNTIRLWDPKSGQCLGDALRGHSKWITSLSWEPIHLVKPGSKPRLASSSKDGTIKIWDTVS--RVCQY 272          
BLAST of notch-1 vs. Ensembl Yeast
Match: DIP2 (Nucleolar protein; specifically associated with the U3 snoRNA, part of the large ribonucleoprotein complex known as the small subunit (SSU) processome, required for 18S rRNA biogenesis, part of the active pre-rRNA processing complex [Source:SGD;Acc:S000004119])

HSP 1 Score: 55.0694 bits (131), Expect = 1.123e-7
Identity = 42/167 (25.15%), Postives = 72/167 (43.11%), Query Frame = 1
Query: 5374 LIAGFQTFDNSTSYMVFDMTMQSRKNGVFKINANTNCTDFINNNEAVTGTESGELI--------IWDLNTVQAVRRIL--ISPNFVDNSESRNPHKDSLTCVTVSNDGSLLATTGLDATVKVWNMEDEKLLYNLNKHKDEIQSLVWSNDNEMLVSGSLDGSIRIWNV 5844
            ++  +Q F+ + ++ V              I +N NC     ++    G+  G+LI        IWD+ T   V ++   + P     S++R       T +    D  LLA    D  +KVW++  + +L N N HK  I  L +      L+SGS D +I +W++
Sbjct:    1 MVKSYQRFEQAAAFGV--------------IASNANCVWIPASSGNSNGSGPGQLITSALEDVNIWDIKTGDLVSKLSDGLPPG---ASDARGAKPAECTYLEAHKDTDLLAVGYADGVIKVWDLMSKTVLLNFNGHKAAITLLQFDGTGTRLISGSKDSNIIVWDL 150          

HSP 2 Score: 52.7582 bits (125), Expect = 6.630e-7
Identity = 44/176 (25.00%), Postives = 84/176 (47.73%), Query Frame = 1
Query: 5335 GIQLLKQTKNGQFLIAGFQTFDNSTSYMVFDMTMQSRKNGVFKINANTNCTDFINNNEAVTGTESGELIIWDL---NTVQAVRRILISPNFVDNSESRNPHKDSLTCVTVSNDGSLLATTGLDATVKVWNMEDEKLLYNLNKHKDEIQSLVWSNDNEMLVSGSLDGSIRIWNVTNG 5853
            G+ ++  T+NG+      Q FD ++S ++ D    +    ++ ++  ++          VTG+    +  WD    N++    +    P    + ++     D + CV VS D   LA + LD TVKV+ ++  K   +L  HK  + S+  S D++M+++ S D +I+IW +  G
Sbjct:  442 GLLVILGTRNGEL-----QLFDLASSSLL-DTIEDAHDAAIWSLDLTSD------GKRLVTGSADKTVKFWDFKVENSLVPGTKNKFLPVLKLHHDTTLELTDDILCVRVSPDDRYLAISLLDNTVKVFFLDSMKFYLSLYGHKLPVLSIDISFDSKMIITSSADKNIKIWGLDFG 605          

HSP 3 Score: 51.9878 bits (123), Expect = 9.619e-7
Identity = 34/115 (29.57%), Postives = 55/115 (47.83%), Query Frame = 1
Query: 5512 VTGTESGELIIWDLNTVQAVRRILISPNFVDNSESRNPHKDSLTCVTVSNDGSLLATTGLDATVKVWNMEDEKLLYNLNKHKDEIQSLVWSNDNEMLVSGSLDGSIRIWNVTNGQ 5856
              G   G + +WDL +    + +L+  NF       N HK ++T +     G+ L +   D+ + VW++  E  LY L  HKD I    W    + L+S S DG I++W++   Q
Sbjct:   95 AVGYADGVIKVWDLMS----KTVLL--NF-------NGHKAAITLLQFDGTGTRLISGSKDSNIIVWDLVGEVGLYKLRSHKDSITGF-WCQGEDWLISTSKDGMIKLWDLKTHQ 195          
BLAST of notch-1 vs. Ensembl Yeast
Match: TAF5 (Subunit (90 kDa) of TFIID and SAGA complexes; involved in RNA polymerase II transcription initiation and in chromatin modification [Source:SGD;Acc:S000000402])

HSP 1 Score: 52.373 bits (124), Expect = 6.731e-7
Identity = 35/126 (27.78%), Postives = 59/126 (46.83%), Query Frame = 1
Query: 5473 NTNCTDFINNNEAV-TGTESGELIIWDLNTVQAVRRILISPNFVDNSESRNPHKDSLTCVTVSNDGSLLATTGLDATVKVWNMEDEKLLYNLNKH-KDEIQSLVWSNDNEMLVSGSLDGSIRIWNV 5844
            + +C  F  N   V TG+      +WD++T  +VR  L              H   +  + V  DG  L+T   D  + VW++   K L  +  H K+ I SL +S +  +L+SG  D ++R+W++
Sbjct:  611 DVDCVSFHPNGCYVFTGSSDKTCRMWDVSTGDSVRLFLG-------------HTAPVISIAVCPDGRWLSTGSEDGIINVWDIGTGKRLKQMRGHGKNAIYSLSYSKEGNVLISGGADHTVRVWDL 723          
BLAST of notch-1 vs. Ensembl Nematostella
Match: EDO48851 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RHH9])

HSP 1 Score: 131.339 bits (329), Expect = 2.582e-30
Identity = 125/388 (32.22%), Postives = 177/388 (45.62%), Query Frame = 1
Query: 2053 KESLFCRACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKP-KPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKV---------DGVMCDYKEPGYAIT 3156
            K     + C+++V +C KN C+N G C N      +C CK   F G+ C+     C+ NPC+NG +C+       C C   GFTG +CE  ++ C  + CQN G+C  + G   C C K  + G+ CE    +C  + C N G C          C C + GF G  C + +  C +N C   G C  +     C C  GFTG  CE+ +  CSK+ C NGG C        C C   F GK CE+    C    C  GG C+  +G   C C          +   +C +  C+NGG+C   +  + C C    +TG+ C   V  C  N CKNGG C+   G + C C   G+ G+ C+Q V         +G +C  +  GY+ T
Sbjct: 1015 KSGFTGKNCEQDVNECSKNPCKNGGVCKN-EHGGYSCACK-AGFTGKNCEQDVNECNKNPCQNGGVCKNEHGGYSCACK-AGFTGKNCEQDMNECSKNPCQNGGVCKNEHGGYSCAC-KAGFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYS--CACKA-GFTGKNCEQDMNECSKNPCQNGGVCKNKHGGYSCACKAGFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCTCKAGFTGKICEQDVNECSKNPCKNGGVCKNEHGGYSCTCKAGFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCTCK-AGFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCTCKA-GFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCT 1393          

HSP 2 Score: 125.561 bits (314), Expect = 1.298e-28
Identity = 121/373 (32.44%), Postives = 168/373 (45.04%), Query Frame = 1
Query: 2098 CPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKP-KPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKV---------DGVMCDYKEPGYAIT 3156
            C    C+N G C  +N    +C CK + F G+ C+     C  NPCKNG +C+       C C   GFTG +CE  ++ C  + CQN G+C  + G   C C K  + G+ CE    +C  + C N G C          C C + GF G  C + +  C +N C   G C        C C  GFTG  CE+ +  CSK+ C NGG C        C C   F GK+CE+    C    C  GG C+  +G   C C          +   +C +  C+NGG+C   +  + C C    +TG+ C   V  C  N CKNGG C+   G + C C   G+ G+ C+Q V         +G +C  +  GY+ T
Sbjct:  992 CSSKPCKNGGTCREVNGA-YSCTCK-SGFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCACK-AGFTGKNCEQDVNECNKNPCQNGGVCKNEHGGYSCAC-KAGFTGKNCEQDMNECSKNPCQNGGVCKNEHGGYS--CACKA-GFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCACKAGFTGKNCEQDMNECSKNPCQNGGVCKNKHGGYSCACKAGFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCTCKAGFTGKICEQDVNECSKNPCKNGGVCKNEHGGYSCTCK-AGFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCTCKA-GFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCT 1355          

HSP 3 Score: 124.405 bits (311), Expect = 3.341e-28
Identity = 123/359 (34.26%), Postives = 170/359 (47.35%), Query Frame = 1
Query: 2065 FCRACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKN-GICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKP-KPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXY-CENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQ 3105
            +C   + +V +C KN C+N G C N      +C C K  F G+ C+     C  NPCKN G+C+       C C   GFTG +CE  ++ C  + C+N G+C  + G   C C K  + G+ CE    +C ++ C N G C          C C + GF G  C + +  C +N C   G C        C C  GFTG  CE+ +  CSK+ C NGG C        C C   F GK+CE+    C    C  GG C+  +G   C C +  +MGK CE+      K  C+NGG+C   +  + C C    +TG+ C   V  C  N CKNGG C+   G + C C   G+ G+ C+Q
Sbjct:  209 YCGNAEFDVNECSKNPCKNGGVCKN-EHGGYSCAC-KVGFTGKNCEQDVNECSVNPCKNGGVCKNEHGGYSCACK-AGFTGKNCEQDVNECSVNPCKNGGVCKNEHGGYSCAC-KVGFTGKNCEQDVNECSVNPCKNGGVCKNEHGGYS--CACKA-GFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCACKAGFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCACKAGFTGKNCEQDVNECSKNPCQNGGVCKNEHGGYSCAC-KAGFMGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCACK-AGFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCACKA-GFTGKNCEQ 557          

HSP 4 Score: 122.865 bits (307), Expect = 9.676e-28
Identity = 114/346 (32.95%), Postives = 158/346 (45.66%), Query Frame = 1
Query: 2071 RACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKP-KPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSL 3075
            + C+++V +C KN CQN G C N      +C CK   F G+ C+     C  NPC+NG +C+       C C   GFTG +CE  ++ C  + C+N G+C  + G   C C K  + G+ CE    +C  + C N G C          C C + GF G  C + +  C +N C   G C        C C  GFTG  CE+ +  CSK+ C NGG C        C C   F GK+CE+    C    C  GG C+  +G   C C          +   +C +  C+NGG+C   +  + C C    +TG+ C   V  C  N CKNGG C+   G + C C  
Sbjct: 1059 KNCEQDVNECNKNPCQNGGVCKN-EHGGYSCACK-AGFTGKNCEQDMNECSKNPCQNGGVCKNEHGGYSCACK-AGFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCAC-KAGFTGKNCEQDMNECSKNPCQNGGVCKNKHGGYS--CACKA-GFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCTCKAGFTGKICEQDVNECSKNPCKNGGVCKNEHGGYSCTCKAGFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCTCKAGFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCTCK-AGFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCTCKA 1396          

HSP 5 Score: 112.079 bits (279), Expect = 1.767e-24
Identity = 108/334 (32.34%), Postives = 151/334 (45.21%), Query Frame = 1
Query: 2215 SCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKP-KPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKV---------DGVMCDYKEPGYAIT 3156
            +C   PCKNG  C+ V     C C  +GFTG +CE  ++ C  + C+N G+C  + G   C C K  + G+ CE    +C  + C N G C          C C + GF G  C + +  C +N C   G C        C C  GFTG  CE+ +  CSK+ C NGG C        C C   F GK+CE+    C    C  GG C+  +G   C C          +   +C +  C+NGG+C   +  + C C    +TG+ C   V  C  N CKNGG C+   G + C C   G+ G+ C+Q V         +G +C  +  GY+ T
Sbjct:  991 TCSSKPCKNGGTCREVNGAYSCTCK-SGFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCAC-KAGFTGKNCEQDVNECNKNPCQNGGVCKNEHGGYS--CACKA-GFTGKNCEQDMNECSKNPCQNGGVCKNEHGGYSCACKAGFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCACKAGFTGKNCEQDMNECSKNPCQNGGVCKNKHGGYSCACKAGFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCTCK-AGFTGKICEQDVNECSKNPCKNGGVCKNEHGGYSCTCKA-GFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCT 1317          

HSP 6 Score: 111.694 bits (278), Expect = 2.455e-24
Identity = 116/358 (32.40%), Postives = 165/358 (46.09%), Query Frame = 1
Query: 2071 RACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKP-KPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCEN--GGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQ 3105
            + C+++V +C  N C+N G C N      +C CK   F G+ C+     C  NPCKNG +C+       C C   GFTG +CE  ++ C  + C+N G+C  + G   C C K  + G+ CE    +C  + C N G C          C C + GF G  C + +  C +N C   G C        C C  GF G  CE+ +  CSK+ C NGG C        C C   F GK+CE+    C    C  GG C+  +G   C C +  + GK CE+       + ++   G+C   +  + C C    +TG+ C   V  C  N CKNGG C+   G + C C   G+ G+ C+Q
Sbjct:  287 KNCEQDVNECSVNPCKNGGVCKN-EHGGYSCACK-VGFTGKNCEQDVNECSVNPCKNGGVCKNEHGGYSCACK-AGFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCAC-KAGFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYS--CACKA-GFTGKNCEQDVNECSKNPCQNGGVCKNEHGGYSCACKAGFMGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCACKAGFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCAC-KAGFTGKNCEQDGLKTIIHLQSIKCGVCKNEHGGYSCACK-AGFTGKNCEQDVNECSVNPCKNGGVCKNEHGGYSCACKA-GFTGKNCEQ 634          

HSP 7 Score: 98.9821 bits (245), Expect = 1.937e-20
Identity = 114/402 (28.36%), Postives = 168/402 (41.79%), Query Frame = 1
Query: 2071 RACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCPL-----DFCLNNGH--------------------CLLNQVNQLPYCVCNSTGFYGYRCNKP-ICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPICSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKP-KPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKV---------DGVMCDYKEPGYAIT 3156
            + C+++V +C KN CQN G C N      +C CK   F G+ C+     C+ NPC+NG +C+       C C   GFTG +CE  ++ C  + C+N G+C  + G   C C K  + G++CE   C +        +   H                    C  N   ++  C     GFY Y  N+P +C   YC   GN                     E   CS   C NGG C  V+ +  C C   F GK+CE+    C    C  GG C+  +G   C C          +   +C +  C+NGG+C   +  + C C    +TG+ C   +  C  N C+NGG C+   G + C C   G+ G+ C+Q V         +G +C  +  GY+  
Sbjct:  797 KNCEQDVNECNKNPCQNGGVCKN-EHGGYSCTCK-AGFTGKNCEQDVNECNKNPCQNGGVCKNEHGGYSCTCK-AGFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCAC-KAGFTGKICEQEICEICGTHAPGWMEGSHPTVAEGIVTRKVCYHWSGKTCHWNNAIRVRNC----GGFYVYELNRPPVCHLRYC---GNA--------------------EFETCSSKPCKNGGTCREVNGAYSCTCKSGFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCACKAGFTGKNCEQDVNECNKNPCQNGGVCKNEHGGYSCACK-AGFTGKNCEQDMNECSKNPCQNGGVCKNEHGGYSCACKA-GFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCA 1165          

HSP 8 Score: 98.5969 bits (244), Expect = 2.072e-20
Identity = 118/411 (28.71%), Postives = 168/411 (40.88%), Query Frame = 1
Query: 2086 NVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPICS-----KDKCINGGKCVVVDRSPFCVCAKDFQGKSCE-------------------KPKPCPVGY-------------CLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKV---------DGVMCDYKEPGYAIT 3156
            +V +C KN CQN G C N      +C CK   F G+ C+     C+ NPC+NG +C+       C C   GFTG +CE  ++ C  + CQN G+C  + G   C C K  + G+ CE    +C  + C N G C          C C + GF G  C + +  C +N C   G C        C C  GFTG  CE+ IC          + G    V +          + GK+C                    +P  C + Y             C  GG CR VNG   C C          +   +C +  C+NGG+C   +  + C C    +TG+ C   V  C  N C+NGG C+   G + C C   G+ G+ C+Q +         +G +C  +  GY+  
Sbjct:  726 DVNECSKNPCQNGGVCKN-EHGGYSCACK-AGFTGKICEQDVNECNKNPCQNGGVCKNEHGGYSCTCK-AGFTGKNCEQDVNECNKNPCQNGGVCKNEHGGYSCTC-KAGFTGKNCEQDVNECNKNPCQNGGVCKNEHGGYS--CTCKA-GFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCACKAGFTGKICEQEICEICGTHAPGWMEGSHPTVAEGIVTRKVCYHWSGKTCHWNNAIRVRNCGGFYVYELNRPPVCHLRYCGNAEFETCSSKPCKNGGTCREVNGAYSCTCKSGFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCACK-AGFTGKNCEQDVNECNKNPCQNGGVCKNEHGGYSCACKA-GFTGKNCEQDMNECSKNPCQNGGVCKNEHGGYSCA 1127          

HSP 9 Score: 89.7373 bits (221), Expect = 1.184e-17
Identity = 94/297 (31.65%), Postives = 125/297 (42.09%), Query Frame = 1
Query: 2071 RACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEK---------------------------PKP----CPVGYCLYGGKCRMVNGMPRCNC 2841
            + C++++ +C KN CQN G C N      +C CK   F G+ C+     C  NPCKNG +C+       C C   GFTG  CE  ++ C  + C+N G+C  + G   C C K  + G+ CE    +C  + C N G C          C C + GF G  C + +  C +N C   G C        C C  GFTG  CE+ +  CSK+ C NGG C        C C   F GK+  K                            +P    C V  CL  GKC    G  +CNC
Sbjct: 1173 KNCEQDMNECSKNPCQNGGVCKN-KHGGYSCACK-AGFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCTCK-AGFTGKICEQDVNECSKNPCKNGGVCKNEHGGYSCTC-KAGFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYS--CTCKA-GFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCTCKAGFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCTCKAGFTGKTANKMLTNVPASTRVIMAESALTAMEDTVVNARPDKNECKVNPCLNNGKCINTPGSYKCNC 1462          

HSP 10 Score: 79.7221 bits (195), Expect = 1.324e-14
Identity = 83/251 (33.07%), Postives = 114/251 (45.42%), Query Frame = 1
Query: 2071 RACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKP-----ICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCE----KPKPC 2775
            + C+++V +C KN C+N G C N      +C CK   F G+ C+     C  NPC+NG +C+       C C   GF G +CE  ++ C  + C+N G+C  + G   C C K  + G+ CE    +C  + C N G C          C C + GF G  C +      I  Q+   K G C        C C  GFTG  CE+ +  CS + C NGG C        C C   F GK+CE    KP+ C
Sbjct:  401 KNCEQDVNECSKNPCKNGGVCKN-EHGGYSCACK-AGFTGKNCEQDVNECSKNPCQNGGVCKNEHGGYSCACK-AGFMGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCAC-KAGFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYS--CACKA-GFTGKNCEQDGLKTIIHLQS--IKCGVCKNEHGGYSCACKAGFTGKNCEQDVNECSVNPCKNGGVCKNEHGGYSCACKAGFTGKNCEQAPSKPREC 642          

HSP 11 Score: 79.337 bits (194), Expect = 1.567e-14
Identity = 81/272 (29.78%), Postives = 113/272 (41.54%), Query Frame = 1
Query: 2071 RACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--------------------------------CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPK 2769
            + C+++V +C KN C+N G C N      +C CK   F G+ C+     C  NPCKNG +C+       C C   GFTG +CE  ++ C  + C+N G+C  + G   C C K  + G+ CE    +C  + C N G C          C C + GF G  C + +  C +N C   G C        C C  GFTG    K +                                C  + C+N GKC+    S  C C  ++ GK CE  K
Sbjct: 1211 KNCEQDVNECSKNPCKNGGVCKN-EHGGYSCTCK-AGFTGKICEQDVNECSKNPCKNGGVCKNEHGGYSCTCK-AGFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCTC-KAGFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYS--CTCKA-GFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCTCKAGFTGKTANKMLTNVPASTRVIMAESALTAMEDTVVNARPDKNECKVNPCLNNGKCINTPGSYKCNCIDEYTGKHCETAK 1475          

HSP 12 Score: 75.485 bits (184), Expect = 2.506e-13
Identity = 69/220 (31.36%), Postives = 97/220 (44.09%), Query Frame = 1
Query: 2071 RACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPICSKDKCINGGKCVVVDRS 2715
            + C+++V +C KN CQN G C N      +C CK   F G+ C+     C  NPCKNG +C+       C C   GFTG +CE  ++ C  + C+N G+C  + G   C C K  + G+ CE         L +  C + +     Y      GF G  C + +  C  N C   G C        C C  GFTG  CE+      +C +  K    DR+
Sbjct:  439 KNCEQDVNECSKNPCQNGGVCKN-EHGGYSCACK-AGFMGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCACK-AGFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCAC-KAGFTGKNCEQDGLKTIIHLQSIKCGVCKNEHGGYSCACKAGFTGKNCEQDVNECSVNPCKNGGVCKNEHGGYSCACKAGFTGKNCEQAPSKPRECRSYKKLDTADRA 654          

HSP 13 Score: 62.7734 bits (151), Expect = 1.652e-9
Identity = 57/176 (32.39%), Postives = 79/176 (44.89%), Query Frame = 1
Query: 2662 CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKP-KPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKV---------DGVMCDYKEPGYAIT 3156
            CSK+ C NGG C        C C   F GK+CE+    C V  C  GG C+  +G   C C          +   +C    C+NGG+C   +  + C C  V +TG+ C   V  C  N CKNGG C+   G + C C   G+ G+ C+Q V         +G +C  +  GY+  
Sbjct:  220 CSKNPCKNGGVCKNEHGGYSCACKVGFTGKNCEQDVNECSVNPCKNGGVCKNEHGGYSCACKAGFTGKNCEQDVNECSVNPCKNGGVCKNEHGGYSCACK-VGFTGKNCEQDVNECSVNPCKNGGVCKNEHGGYSCACKA-GFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCA 393          
BLAST of notch-1 vs. Ensembl Nematostella
Match: EDO46969 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RNQ6])

HSP 1 Score: 106.686 bits (265), Expect = 3.760e-24
Identity = 114/319 (35.74%), Postives = 153/319 (47.96%), Query Frame = 1
Query: 2218 CDPNPCKN-GIC-----QIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCPLDFCLNNGHCLLNQVNQLPY-CVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI---CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKP-KPCPVGY-CLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXY--CENGGICSIINNVFICNCSNVSYTGERCTNKVG--CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            C PNPC+N GIC     Q  G   +C    +GF+G  C+  I+ C  + CQN G C+ K G   C+C K  + G+ CE   C  + C N G C  +      Y CVC S GF G RC   I  C +N C   G+C+ +  S +C C  G+TG  CE+ +    S + C NGG C        C CA  + GK C+K    C     C  GG C    G   C C  + Y GK CEK          C+NGG+C+     + C C++  YTG+ C   V      N CKNGG C    G++ C C+ +GY G+ C+  V+
Sbjct:    2 CSPNPCENGGICADDRGQASGYRCVCR---SGFSGARCQSDINECKKNPCQNGGDCVNKHGSHLCNC-KLGWTGKNCEKAPCSPNPCENGGKCADDLGQDSGYRCVCRS-GFSGARCQSDINECKKNPCQNGGDCVNKHGSHLCNCKLGWTGRNCEEDVNECASSNPCKNGGVCTNTPGGFSCKCASGYTGKECKKDVNECASSNPCKNGGVCTNSPGGYSCKCA-SGYTGKNCEKDVNECASSNPCKNGGVCTNSPGGYSCKCAS-GYTGKNCEKDVNECASSNPCKNGGVCANSPGRYSCECA-SGYTGKNCEIDVN 312          

HSP 2 Score: 93.9745 bits (232), Expect = 4.937e-20
Identity = 118/363 (32.51%), Postives = 167/363 (46.01%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG------ICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI---CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI---CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKP-KPCPVGY-CLYGGKCRMVNGMPRCNCTQTNYMGXXXX--XXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCT-NKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCD 3102
            CQ ++ +C KN CQN G C N + + + C+CK   + G+ C+  +  C PNPC+NG      + Q  G   +C    +GF+G  C+  I+ C  + CQN G C+ K G   C+C K  + G+ CE    +C       NG    N       C C ++G+ G  C K +      N C   G C        C C  G+TG  CEK +    S + C NGG C        C CA  + GK+CEK    C     C  GG C    G   C C  + Y GK CE    +      C+NGG+C+     + C C++  YTG+ C  ++  C  + C+NGG C    G + C C   GY G+ C+
Sbjct:   36 CQSDINECKKNPCQNGGDCVNKHGSHL-CNCK-LGWTGKNCE--KAPCSPNPCENGGKCADDLGQDSGYRCVCR---SGFSGARCQSDINECKKNPCQNGGDCVNKHGSHLCNC-KLGWTGRNCEEDVNECASSNPCKNGGVCTNTPGGF-SCKC-ASGYTGKECKKDVNECASSNPCKNGGVCTNSPGGYSCKCASGYTGKNCEKDVNECASSNPCKNGGVCTNSPGGYSCKCASGYTGKNCEKDVNECASSNPCKNGGVCANSPGRYSCECA-SGYTGKNCEIDVNECASSNPCKNGGVCTNSPGGYSCKCAS-GYTGKNCEKDEDKCKVSPCQNGGKCINSDGGYSCEC-KGGYSGKHCE 385          

HSP 3 Score: 82.4185 bits (202), Expect = 3.360e-16
Identity = 112/359 (31.20%), Postives = 158/359 (44.01%), Query Frame = 1
Query: 2098 CPKNYCQNKGRCYNI--NETKIACDCKKTQFYGEFCDIKRPSCDPNPCKN-GICQIVGNNRICNCTGTGFTGFDCEISRCFNHKCQNNGICILKQGIP---ECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI---CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI---CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKP-KPCPVGY-CLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXY--CENGGICSIINNVFICNCSNVSYTGERCTNKVG--CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            C  N C+N G C +     +   C C+ + F G  C      C  NPC+N G C     + +CNC   G+TG +CE + C  + C+N G C    G      C C ++ + G  C++   +C  + C N G C+    + L  C     G+ G  C + +      N C   G C        C C  G+TG +C+K +    S + C NGG C        C CA  + GK+CEK    C     C  GG C    G   C C  + Y GK CEK          C+NGG+C+     + C C++  YTG+ C   V      N CKNGG C    G + C C+ +GY G+ C++  D
Sbjct:    2 CSPNPCENGGICADDRGQASGYRCVCR-SGFSGARCQSDINECKKNPCQNGGDCVNKHGSHLCNCK-LGWTGKNCEKAPCSPNPCENGGKCADDLGQDSGYRCVC-RSGFSGARCQSDINECKKNPCQNGGDCVNKHGSHLCNC---KLGWTGRNCEEDVNECASSNPCKNGGVCTNTPGGFSCKCASGYTGKECKKDVNECASSNPCKNGGVCTNSPGGYSCKCASGYTGKNCEKDVNECASSNPCKNGGVCTNSPGGYSCKCA-SGYTGKNCEKDVNECASSNPCKNGGVCANSPGRYSCECAS-GYTGKNCEIDVNECASSNPCKNGGVCTNSPGGYSCKCA-SGYTGKNCEKDED 351          

HSP 4 Score: 63.1586 bits (152), Expect = 5.252e-10
Identity = 77/243 (31.69%), Postives = 106/243 (43.62%), Query Frame = 1
Query: 2071 RACQENVKKCPK-NYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSC-DPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCE--ISRCFN-HKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI---CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKP--ICSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCE 2760
            R C+E+V +C   N C+N G C N      +C C  + + G+ C      C   NPCKNG +C        C C  +G+TG +CE  ++ C + + C+N G+C    G   C C  + Y G+ CE    +C       NG    N   +   C C ++G+ G  C   +      N C   G C        C C  G+TG  CEK    C    C NGGKC+  D    C C   + GK CE
Sbjct:  149 RNCEEDVNECASSNPCKNGGVCTNT-PGGFSCKCA-SGYTGKECKKDVNECASSNPCKNGGVCTNSPGGYSCKCA-SGYTGKNCEKDVNECASSNPCKNGGVCTNSPGGYSCKCA-SGYTGKNCEKDVNECASSNPCKNGGVCANSPGRY-SCEC-ASGYTGKNCEIDVNECASSNPCKNGGVCTNSPGGYSCKCASGYTGKNCEKDEDKCKVSPCQNGGKCINSDGGYSCECKGGYSGKHCE 385          
BLAST of notch-1 vs. Ensembl Nematostella
Match: EDO33795 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SR75])

HSP 1 Score: 103.219 bits (256), Expect = 1.432e-23
Identity = 106/311 (34.08%), Postives = 143/311 (45.98%), Query Frame = 1
Query: 2098 CPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGICQIVGNNRI----CNCTGTGFTGFDC-EISRCFNHKCQNNGICILKQGIPECDCTKTV-YEGQLCETPKCPLDFCLNNGHCLLNQVNQLPYCVCN-STGFYGYRCNKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCE---KPICSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXX--XXXYCENGGICSIINNVFICNCSNVSYTGERCTNK 2994
            C  N C+N G CY++ +    C C +  F GE C+ +   C PNPC+NG     G   +    C C   GF GFDC EI+ C  + C+N G C  K G    DCT  + ++G  CE   C  + CL+ G C    V+++    CN   G+ G  C   +C  N C   G+CL       C C  G+ G  CE   + +C  + C NG  CV  D S  C C   + G  C+  + C    C  GG C       RC C Q NY G  CE+          C NGG CS +NN  +C C  V + G +C ++
Sbjct:   10 CEPNPCRNGGTCYDVGQ-GYECTCARG-FKGENCE-EINKCHPNPCRNGG-MCTGTTSVTGYQCTCR-EGFKGFDCEEINLCVPNPCKNAGTCTEKGGGRY-DCTCPIGFKGVTCEGHICFSNPCLHGGSC----VDEMYGFRCNCPIGYNGVTCQNHVCRPNPCQNGGSCLEEGGLGRCICQMGYHGQHCESESQNVCHPNPCHNGATCVATDSSFDCDCMAGWTGPLCQTRQYCIPNPCQNGGTCVPQENGYRCTC-QANYEGNDCERKSANPCSPNPCRNGGTCSEMNNAAVCACG-VQFEGNQCESE 308          

HSP 2 Score: 90.5077 bits (223), Expect = 2.891e-19
Identity = 87/262 (33.21%), Postives = 119/262 (45.42%), Query Frame = 1
Query: 2083 ENVKKCPKNYCQNKGRCYNINE-TKIACDCKKTQFYGEFCDIKRPSCDPNPCKN-GICQIVGNNRI-CNCTGTGFTGFDCEISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRC---NKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCE-KPICSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEK--PKPCPVGYCLYGGKCRMVNGMPRCNC 2841
            E + KC  N C+N G C      T   C C++  F G  C+ +   C PNPCKN G C   G  R  C C   GF G  CE   CF++ C + G C+ +     C+C    Y G  C+   C  + C N G CL  +   L  C+C   G++G  C   ++ +C  N C     C+  D S  C C  G+TG  C+ +  C  + C NGG CV  +    C C  +++G  CE+    PC    C  GG C  +N    C C
Sbjct:   42 EEINKCHPNPCRNGGMCTGTTSVTGYQCTCREG-FKGFDCE-EINLCVPNPCKNAGTCTEKGGGRYDCTCP-IGFKGVTCEGHICFSNPCLHGGSCVDEMYGFRCNC-PIGYNGVTCQNHVCRPNPCQNGGSCL--EEGGLGRCIC-QMGYHGQHCESESQNVCHPNPCHNGATCVATDSSFDCDCMAGWTGPLCQTRQYCIPNPCQNGGTCVPQENGYRCTCQANYEGNDCERKSANPCSPNPCRNGGTCSEMNNAAVCAC 296          

HSP 3 Score: 88.1965 bits (217), Expect = 1.780e-18
Identity = 95/308 (30.84%), Postives = 132/308 (42.86%), Query Frame = 1
Query: 2209 RPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCE-ISRCFNHKCQNNGICILKQGIPECDCT-KTVYEGQLCETPK-CPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPICSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKP--CPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG--CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQK 3108
            R  C+PNPC+NG  C  VG    C C   GF G +CE I++C  + C+N G+C     +    CT +  ++G  CE    C  + C N G C      +   C C   GF G  C   IC  N C   G+C+       C C  G+ G  C+  +C  + C NGG C+       C+C   + G+ CE      C    C  G  C   +    C+C    + G  C+  + C    C+NGG C    N + C C   +Y G  C  K    C  N C+NGG C        C C +  + G QC+ +
Sbjct:    7 RSLCEPNPCRNGGTCYDVGQGYECTCA-RGFKGENCEEINKCHPNPCRNGGMCTGTTSVTGYQCTCREGFKGFDCEEINLCVPNPCKNAGTCTEKGGGRYD-CTC-PIGFKGVTCEGHICFSNPCLHGGSCVDEMYGFRCNCPIGYNGVTCQNHVCRPNPCQNGGSCLEEGGLGRCICQMGYHGQHCESESQNVCHPNPCHNGATCVATDSSFDCDC-MAGWTGPLCQTRQYCIPNPCQNGGTCVPQENGYRCTCQ-ANYEGNDCERKSANPCSPNPCRNGGTCSEMNNAAVCACGVQ-FEGNQCESE 308          

HSP 4 Score: 67.781 bits (164), Expect = 8.709e-12
Identity = 69/235 (29.36%), Postives = 99/235 (42.13%), Query Frame = 1
Query: 2083 ENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPC-KNGICQIVGNNRICNCTGTGFTGFDCEISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPK---CPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCN-KPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI---CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEK 2763
            E +  C  N C+N G C      +  C C    F G  C+     C  NPC   G C        CNC   G+ G  C+   C  + CQN G C+ + G+  C C +  Y GQ CE+     C  + C N   C+    +    C+    G+ G  C  +  C  N C   G C+ +++   C C   + G+ CE+     CS + C NGG C  ++ +  C C   F+G  CE 
Sbjct:   81 EEINLCVPNPCKNAGTCTEKGGGRYDCTC-PIGFKGVTCEGH--ICFSNPCLHGGSCVDEMYGFRCNCP-IGYNGVTCQNHVCRPNPCQNGGSCLEEGGLGRCIC-QMGYHGQHCESESQNVCHPNPCHNGATCVATDSSFDCDCM---AGWTGPLCQTRQYCIPNPCQNGGTCVPQENGYRCTCQANYEGNDCERKSANPCSPNPCRNGGTCSEMNNAAVCACGVQFEGNQCES 307          
BLAST of notch-1 vs. Ensembl Nematostella
Match: EDO30306 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T163])

HSP 1 Score: 100.908 bits (250), Expect = 1.257e-21
Identity = 119/372 (31.99%), Postives = 170/372 (45.70%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYN-INETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNR--ICNCTGTGFTGFDCE----ISRCFNHKCQNNGICILKQGIPECDCT-KTVYEGQLCE--TPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSA--VCYCDEGFTGDKCEKPI--CSKDKCINGGKCV-VVDRSPF-CVCAKDFQGKSCE-KPKPCPVGYCLYGGKC--RMVNGMPRCNCTQTNYMG-XXXXXXXXXXXXYCENGGICS--IINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCS-LTGYGGEQCDQKV 3111
            C+  V+ C  + C+N G C N  + T   C C  +++ G  C+ +   CD +PCKNG  C    +N    C C  + +TG +CE    +  C +  C+N   C      P   CT  +V+ G  CE  TP C  + C N+G C     N    C C S  + G  C   +  C  + C   G C+ + D++   C C  G+TG +CE  +  C    C NGG C    D S F C CA  + G  CE + +PC    C  GG C  +  N    C C  + Y G +   + + C    C+NGG C+    N  + C C +  YTG  C  +V  C  + CKNGGAC       G  C+  +GY G +C+ +V
Sbjct:  132 CESQVQPCDSSPCKNGGACTNKPDNTGYTCACP-SEYTGTECETQVQPCDSSPCKNGGACANKADNSGYTCAC-ASAYTGIECETVLTVQPCDSSPCKNGATCTNSADNPGYMCTCSSVFTGSTCEIVTP-CESNPCKNDGSCANKPNNTGYTCTCTSE-YTGTECETQVQPCDSSPCKNGGACVNKADNSGYTCACASGYTGIECETQVQPCDSSPCKNGGACANKADNSGFTCACASGYTGIECENQVQPCESSPCKNGGACVNKADNSGYTCACA-SGYTGIECETQVQPCDSSPCKNGGSCTNKPDNTGYTCTCPS-EYTGTECETQVQPCDSSPCKNGGACANKADNSGYMCACASGYTGIECETQV 497          

HSP 2 Score: 97.0561 bits (240), Expect = 2.360e-20
Identity = 123/370 (33.24%), Postives = 174/370 (47.03%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYN-INETKIACDCKKTQFYGEFCD--IKRPSCDPNPCKNG-ICQIVGNNR--ICNCTGTGFTGFDCEI-SRCFNHKCQNNGICILKQGIPECDCTKTV-YEGQLCETPKCPLDF--CLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSA--VCYCDEGFTGDKCEKPI--CSKDKCINGGKCV-VVDRSPF-CVCAKDFQGKSCE-KPKPCPVGYCLYGGKC--RMVNGMPRCNCTQTNYMGXXXXXXXXXXXXY-CENGGICS--IINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNC-SLTGYGGEQCDQK 3108
            C+  V+ C  + C+N G C N  + +   C C  + + G  C+  +    CD +PCKNG  C    +N   +C C+   FTG  CEI + C ++ C+N+G C  K       CT T  Y G  CET   P D   C N G C+    N    C C S G+ G  C   +  C  + C   G C  + D++   C C  G+TG +CE  +  C    C NGG CV   D S + C CA  + G  CE + +PC    C  GG C  +  N    C C  + Y G +CE   +  +   C+NGG C+    N+ ++C C++  YTG  C  +V  C  + CKNGGAC     K G  C   + Y G +C+ +
Sbjct:  172 CETQVQPCDSSPCKNGGACANKADNSGYTCACA-SAYTGIECETVLTVQPCDSSPCKNGATCTNSADNPGYMCTCSSV-FTGSTCEIVTPCESNPCKNDGSCANKPNNTGYTCTCTSEYTGTECETQVQPCDSSPCKNGGACVNKADNSGYTCACAS-GYTGIECETQVQPCDSSPCKNGGACANKADNSGFTCACASGYTGIECENQVQPCESSPCKNGGACVNKADNSGYTCACASGYTGIECETQVQPCDSSPCKNGGSCTNKPDNTGYTCTC-PSEYTGTECETQVQPCDSSPCKNGGACANKADNSGYMCACAS-GYTGIECETQVQPCDSSPCKNGGACTNKPDKSGYTCICPSEYTGTECETQ 536          

HSP 3 Score: 87.0409 bits (214), Expect = 3.451e-17
Identity = 116/372 (31.18%), Postives = 165/372 (44.35%), Query Frame = 1
Query: 2089 VKKCPKNYCQNKGRCYN-INETKIACDCKKTQFYGEFCDIKRPSCDPNPCKN-GICQIVGNNR--ICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPE-----CDCTKTVYEGQLCETPKCPLDF--CLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI----CPQNYCTKNGNCLVRDDSA--VCYCDEGFTGDKCE-KPICSKDKCINGGKCVVVDRSP--FCVCAKDFQGKSCE-KPKPCPVGYCLYGGKC--RMVNGMPRCNCTQTNYMG-XXXXXXXXXXXXYCENGGICS--IINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGAC--EIHRGKFGCNCSLTGYGGEQCDQKV 3111
            V+ C  + C+N G C N  + +   C C  + + G  C+ +   CD +PCKN G C    +N    C C  +G+TG +CE  +  C +  C+N G C  K   P+     C C  + Y G  CET   P D   C N G C     N    C C S  + G  C   +    C  + C     C    D+   +C C   FTG  CE    C  + C N G C     +    C C  ++ G  CE + +PC    C  GG C  +  N    C C  + Y G +   + + C    C+NGG C+    N+ F C C++  YTG  C N+V  C  + CKNGGAC  +     + C C+ +GY G +C+ +V
Sbjct:   56 VQPCDSSPCKNGGACVNKADHSGYTCACA-SGYTGIECETRVQPCDSSPCKNGGACANKADNSGYTCAC-ASGYTGIECESQVQPCDSSPCKNGGACTNK---PDNTGYTCAC-PSEYTGTECETQVQPCDSSPCKNGGACANKADNSGYTCACAS-AYTGIECETVLTVQPCDSSPCKNGATCTNSADNPGYMCTCSSVFTGSTCEIVTPCESNPCKNDGSCANKPNNTGYTCTCTSEYTGTECETQVQPCDSSPCKNGGACVNKADNSGYTCACA-SGYTGIECETQVQPCDSSPCKNGGACANKADNSGFTCACAS-GYTGIECENQVQPCESSPCKNGGACVNKADNSGYTCACA-SGYTGIECETQV 417          

HSP 4 Score: 83.5741 bits (205), Expect = 3.460e-16
Identity = 111/379 (29.29%), Postives = 162/379 (42.74%), Query Frame = 1
Query: 2089 VKKCPKNYCQNKGRCYN-INETKIACDCKKTQFYGEFCDIKRPS------------CDPNPCKNG---ICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCT-KTVYEGQLCETPKCPLDF--CLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSA--VCYCDEGFTGDKCEKPI----CSKDKCINGGKCVVVDRSP--FCVCAKDFQGKSCEKPKPCPVGYCLYGGKC--RMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGIC--SIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGAC--EIHRGKFGCNCSLTGYGGEQCDQKV 3111
            V+ C  + C+N G C N  + T   C C  +++ G  C+ +  +            CD +PCKNG   + +   +   C C  +G+TG +CE  +  C +  C+N G C  K       C   + Y G  CE+   P D   C N G C     N    C C S  + G  C   +  C  + C   G C  + D++   C C   +TG +CE  +    C    C NG  C     +P   C C+  F G +CE   PC    C   G C  +  N    C CT      +   + + C    C+NGG C     N+ + C C++  YTG  C  +V  C  + CKNGGAC  +     F C C+ +GY G +C+ +V
Sbjct:    4 VQPCDSSPCKNGGSCTNKPDNTGYTCTC-PSEYTGTECETQDSTIDKFVITFKVQPCDSSPCKNGGACVNKADHSGYTCAC-ASGYTGIECETRVQPCDSSPCKNGGACANKADNSGYTCACASGYTGIECESQVQPCDSSPCKNGGACTNKPDNTGYTCACPSE-YTGTECETQVQPCDSSPCKNGGACANKADNSGYTCACASAYTGIECETVLTVQPCDSSPCKNGATCTNSADNPGYMCTCSSVFTGSTCEIVTPCESNPCKNDGSCANKPNNTGYTCTCTSEYTGTECETQVQPCDSSPCKNGGACVNKADNSGYTCACAS-GYTGIECETQVQPCDSSPCKNGGACANKADNSGFTCACA-SGYTGIECENQV 377          

HSP 5 Score: 80.4925 bits (197), Expect = 3.332e-15
Identity = 88/269 (32.71%), Postives = 119/269 (44.24%), Query Frame = 1
Query: 2059 SLFCRACQENVKKCPKNYCQNKGRCYN-INETKIACDCKKTQFYGEFCDIKRPSCDPNPCKN-GICQIVGNNR--ICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIP--ECDCTKTVYEGQLCE--TPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSA--VCYCDEGFTGDKCEKPI--CSKDKCINGGKCV-VVDRSPF-CVCAKDFQGKSCE-KPKPCPVGYCLYGGKC 2808
            S+F  +  E V  C  N C+N G C N  N T   C C  +++ G  C+ +   CD +PCKN G C    +N    C C  +G+TG +CE  +  C +  C+N G C  K       C C  + Y G  CE     C    C N G C+    N    C C S G+ G  C   +  C  + C   G+C  + D+    C C   +TG +CE  +  C    C NGG C    D S + C CA  + G  CE + +PC    C  GG C
Sbjct:  247 SVFTGSTCEIVTPCESNPCKNDGSCANKPNNTGYTCTC-TSEYTGTECETQVQPCDSSPCKNGGACVNKADNSGYTCAC-ASGYTGIECETQVQPCDSSPCKNGGACANKADNSGFTCAC-ASGYTGIECENQVQPCESSPCKNGGACVNKADNSGYTCACAS-GYTGIECETQVQPCDSSPCKNGGSCTNKPDNTGYTCTCPSEYTGTECETQVQPCDSSPCKNGGACANKADNSGYMCACASGYTGIECETQVQPCDSSPCKNGGAC 511          
BLAST of notch-1 vs. Ensembl Nematostella
Match: EDO33199 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SSU4])

HSP 1 Score: 98.9821 bits (245), Expect = 1.760e-21
Identity = 112/351 (31.91%), Postives = 159/351 (45.30%), Query Frame = 1
Query: 2083 ENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKN-GICQIVGNNRICNCTGTGFTGFDCEI-SRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCET--PKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCN-KPICPQNYCTKNGNC--LVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQK 3108
            E   KC  N C+N G C  +++    C C + ++ G  CD++   C  +PC N G C    ++  C C   GF+G  CE+ S+C N+ C+N G C        C C    + G  CE     C    CLN G C LNQ   +  CVC   GF G+ C  +  C  N C   G C  ++ +D   C C  G+ G  C++ I  C    C NG  C +   +  C+C + F+G +C     C    C+ GG C       RC C +  Y G  CE+  KC    C NGG+C   +  F C C++  Y G  C     C  N C++GG C      + C+C   G+ G  C+ +
Sbjct:   33 EERNKCQPNPCRNGGSCTEVDD-GFECAC-QAEYKGTTCDVEN-RCYISPCLNGGTCMSTASSFQCLCL-EGFSGSSCEVESKCRNNPCRNGGSCFDHHNSYTCGCLPG-FSGVNCEAIISVCDSSPCLNGGTC-LNQGPNMFRCVCQH-GFKGHNCEMEKKCEPNPCQNRGICREVIDEDDYRCDCIHGYRGRDCDEQINLCDSSPCGNGATCTMFGATFHCLCPEGFRGLTCLDIDKCHAMPCMNGGTCIATLNNYRCQCPE-GYRGSNCEEELKCHPNPCLNGGMCFENSGGFTCKCAD-GYRGINCAEHDHCHPNPCRHGGVCAGDGDDYVCSCR-NGWAGTNCEDE 373          

HSP 2 Score: 55.8398 bits (133), Expect = 1.127e-7
Identity = 52/163 (31.90%), Postives = 71/163 (43.56%), Query Frame = 1
Query: 2554 CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCE-KPICSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGAC 3036
            C  + C   G C    +   C C  GF G  CE +  C  + C NGG C  VD    C C  +++G +C+    C +  CL GG C       +C C +  + G  CE   KC    C NGG C   +N + C C    ++G  C   +  C  + C NGG C
Sbjct:    1 CSNSPCQNGGTCNEVKEGYECICPHGFKGQDCEERNKCQPNPCRNGGSCTEVDDGFECACQAEYKGTTCDVENRCYISPCLNGGTCMSTASSFQCLCLE-GFSGSSCEVESKCRNNPCRNGGSCFDHHNSYTCGCL-PGFSGVNCEAIISVCDSSPCLNGGTC 161          

HSP 3 Score: 52.7582 bits (125), Expect = 1.257e-6
Identity = 67/235 (28.51%), Postives = 85/235 (36.17%), Query Frame = 1
Query: 2071 RACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDC-EISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETP-KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNK-PICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCE-KPICSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCE 2760
            R C E +                                          CD +PC NG  C + G    C C   GF G  C +I +C    C N G CI       C C +  Y G  CE   KC  + CLN G C  N       C   + G+ G  C +   C  N C   G C    D  VC C  G+ G  CE +  CS + C++GG CV       C C   + G++CE
Sbjct:  219 RDCDEQINL----------------------------------------CDSSPCGNGATCTMFGATFHCLCP-EGFRGLTCLDIDKCHAMPCMNGGTCIATLNNYRCQCPEG-YRGSNCEEELKCHPNPCLNGGMCFENSGGFTCKC---ADGYRGINCAEHDHCHPNPCRHGGVCAGDGDDYVCSCRNGWAGTNCEDEDRCSPNPCLHGGVCVAKGYRYECHCPNHYSGENCE 408          
BLAST of notch-1 vs. Ensembl Medaka
Match: ENSORLT00000041634.1 (crumbs cell polarity complex component 2 [Source:NCBI gene;Acc:101175660])

HSP 1 Score: 121.709 bits (304), Expect = 5.179e-27
Identity = 141/524 (26.91%), Postives = 213/524 (40.65%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCD-EGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKP-KPCPVGYCLYGGKC------RMVNGMPRCNCTQTNYMGXX---------------XXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNC-----SLTGYGGEQCDQKVDGVM---CDYKE-------------------PGYAI----TAFKPPMVSSGIV-------------------TSMGFQTFVKT---GTLFCYETADDKYWLIKLVNGRLVADING---ISFNMKTVVSDGRYHFLKVSRDE 3381
            CQ++V  C    CQN G C ++ +    C C    + GE C+     C   PC+NG IC+   N   C C   GF G  CE  I  C +  CQNNG C+ +     C+C    +EG  CE    +C L  C N G C+ +    +  C C + GF G  C   I  C    C  +G C+   +S  C CD  GF GD CE  I  C+ D C +GG C+       CVC   ++G++C+     C  G C  GG C      R    +P  + T  +Y                        +C    C++GG C  + N + C C +  +TG  C   +  C  N CKNG  CE     + C+C     S   +GG+ CD ++ G +   C +++                   PG++     T+      S G +                     +  Q   +T     L  Y  + ++++ ++LV G L A +     +  +    V+DGR++ + V+ DE
Sbjct:  144 CQDSVTTCSTQACQNGGTCVDVPDAGHQCQCVPG-YQGENCEENVDECWSEPCQNGAICKDGVNGYQCFCV-PGFQGSHCELDIKECASQPCQNNGTCLDEVDHYTCECAPG-FEGMNCEVEIDECELHPCQNGGICIDHIA--MYSCEC-TAGFQGQDCEVNIDECASMPCLNDGRCIDGINSYECDCDGTGFEGDHCEDNIQECASDPCQHGGTCLDGINQYKCVCWPGYEGENCQMDIDECEKGPCDNGGTCFQRSDVRNYKNLPELSVTTFSYGTAAGFICLCMAGFTGHNCSVNVDECESAPCQHGGRCQDLVNSYHCLCPD-GFTGVHCEEDINECASNPCKNGATCEDSVNSYKCHCPKAEGSQEPWGGQDCDVRLVGCLQHQCQHEKSCVPVLKDDGAHSYMCMCLPGWSGELCNTSTTFSFSSEGYIYLRLPGSKNRTKRGADDKRQRLHMQLRFRTTLPDMLLLYRGSMERFFTLELVQGSLQARVKSARVLQVSHPGPVNDGRWYDVTVAMDE 660          

HSP 2 Score: 82.0333 bits (201), Expect = 7.294e-15
Identity = 94/359 (26.18%), Postives = 139/359 (38.72%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRC-YNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGICQIVGNNRICNCTGTGFTGFDC--EISRCFNHKCQN-NGICILKQGIPECDCTKTVYEGQLCE--TPKCPLDFCLNNGHCL-LNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCE-KPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            C     +C  + C+N   C Y+  E    C     ++ G+ C+    +C    C N   Q   +  IC+C   G+TG  C  E+  C ++ C      C+       C C    + G+ C+     C    C N G C+ +        CV    G+ G  C + +  C    C     C    +   C+C  GF G  CE  I  C+   C N G C+       C CA  F+G +CE +   C +  C  GG C     M  C CT             +C    C N G C    N + C+C    + G+ C + +  C  + C++GG C     ++ C C   GY GE C   +D
Sbjct:   27 CTAAADRCLSSPCKNGATCLYHEGEYVCVCPNFPVKYTGKHCEELYDACSTTSCTNCTSQPGTDEFICHCP-DGYTGPSCEQEVDECHSNPCMGVRSYCVDGANSYACHC-PIGWAGENCQDSVTTCSTQACQNGGTCVDVPDAGHQCQCV---PGYQGENCEENVDECWSEPCQNGAICKDGVNGYQCFCVPGFQGSHCELDIKECASQPCQNNGTCLDEVDHYTCECAPGFEGMNCEVEIDECELHPCQNGGICIDHIAMYSCECTAGFQGQDCEVNIDECASMPCLNDGRCIDGINSYECDCDGTGFEGDHCEDNIQECASDPCQHGGTCLDGINQYKCVC-WPGYEGENCQMDID 379          

HSP 3 Score: 76.6406 bits (187), Expect = 2.580e-13
Identity = 90/368 (24.46%), Postives = 138/368 (37.50%), Query Frame = 1
Query: 1705 IQDNTWHRVIINLNKPKEILYIHIDDVESLTNEIKLKNSKKELAEMNFISLSLGGISDNSQYTQFYNLLRKKNPEVSKLFSGPDELKFIGCLGDILVINSSYSGNLIQKPNVNSFPKESLFCR--------ACQENVKKCPKNYCQNKGRCYN-INETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPK 2769
            I D  WH + +++ +P + L        SLT +           +   +S  +GG           N L + N  +++        KF GCLG++ V      G  +   N+   P++S F R         CQ     C    C N+G C +  N+   +C   +  + GE C+ +   C  +PC  G C+ +  +  C+C   G+ G +CE  +  C    C N G C    G   C C    ++G+ C+                     + P   C++                 C   G C+  D    C C  GF+G +CE  I  CS + C+NG  C        CVC   F GK CE  K
Sbjct: 1102 IADGAWHHIQLSMVEPAQSL-----SRWSLTVD----------GQRAGVSFGVGG---------NLNFLNESNIWLAE--------KFTGCLGEVRV-----GGVYLPLVNITDAPQQSQFTRLGGHEPILGCQ-GSPVCDSQPCLNQGVCQDHFNDFNCSC---RPGWEGEVCEAQTDECSSSPCLYGKCKDLLADYHCDCE-PGYKGKNCEEEVDNCLEFSCINGGRCEETVGTHSCSCPPG-FKGKRCQW--------------------RFPPVACDAN--------------TKCFNEGVCVGGDSGGNCSCKPGFSGARCEAEIDECSSNPCLNGATCQDQLNHFKCVCVPGFHGKFCENNK 1392          

HSP 4 Score: 63.1586 bits (152), Expect = 3.773e-9
Identity = 90/330 (27.27%), Postives = 121/330 (36.67%), Query Frame = 1
Query: 2188 GEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTG--TGFTGFDCE--ISRCFNHKCQNNGICILKQGIPE--CDCTKTVYEGQLCE--TPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCL-VRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCE-KPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERC-TNKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVDGVMCD 3129
            G  C      C  +PCKNG  C       +C C      +TG  CE     C    C N   C  + G  E  C C    Y G  CE    +C  + C+      ++  N    C C   G+ G  C   +  C    C   G C+ V D    C C  G+ G+ CE+ +  C  + C NG  C        C C   FQG  CE   K C    C   G C        C C           +  +C    C+NGGIC     ++ C C+   + G+ C  N   C    C N G C      + C+C  TG+ G+ C+  +     D
Sbjct:   24 GLLCTAAADRCLSSPCKNGATCLYHEGEYVCVCPNFPVKYTGKHCEELYDACSTTSCTN---CTSQPGTDEFICHCPDG-YTGPSCEQEVDECHSNPCMGVRSYCVDGANSYA-CHC-PIGWAGENCQDSVTTCSTQACQNGGTCVDVPDAGHQCQCVPGYQGENCEENVDECWSEPCQNGAICKDGVNGYQCFCVPGFQGSHCELDIKECASQPCQNNGTCLDEVDHYTCECAPGFEGMNCEVEIDECELHPCQNGGICIDHIAMYSCECT-AGFQGQDCEVNIDECASMPCLNDGRCIDGINSYECDCDGTGFEGDHCEDNIQECASD 346          

HSP 5 Score: 52.373 bits (124), Expect = 7.402e-6
Identity = 55/194 (28.35%), Postives = 84/194 (43.30%), Query Frame = 1
Query: 2545 KPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKP-KPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXX----XXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCD 3102
             P+C    C   G C    +   C C  G+ G+ CE     CS   C+ G KC  +     C C   ++GK+CE+    C    C+ GG+C    G   C+C    + GK+C+             C N G+C   ++   C+C    ++G RC  ++  C  N C NG  C+     F C C + G+ G+ C+
Sbjct: 1200 SPVCDSQPCLNQGVCQDHFNDFNCSCRPGWEGEVCEAQTDECSSSPCLYG-KCKDLLADYHCDCEPGYKGKNCEEEVDNCLEFSCINGGRCEETVGTHSCSCP-PGFKGKRCQWRFPPVACDANTKCFNEGVCVGGDSGGNCSC-KPGFSGARCEAEIDECSSNPCLNGATCQDQLNHFKCVC-VPGFHGKFCE 1389          
BLAST of notch-1 vs. Ensembl Medaka
Match: ENSORLT00000020612.2 (crumbs cell polarity complex component 2 [Source:NCBI gene;Acc:101175660])

HSP 1 Score: 120.553 bits (301), Expect = 1.132e-26
Identity = 141/524 (26.91%), Postives = 211/524 (40.27%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCD-EGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKP-KPCPVGYCLYGGKC------RMVNGMPRCNCTQTNYMGXX---------------XXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNC-----SLTGYGGEQCDQKVDGVM---CDYKE-------------------PGYA------ITAFKPPMVSSGIVTSMGFQTFVKTGT--------------------LFCYETADDKYWLIKLVNGRLVADING---ISFNMKTVVSDGRYHFLKVSRDE 3381
            CQ++V  C    CQN G C ++ +    C C    + GE C+     C   PC+NG IC+   N   C C   GF G  CE  I  C +  CQNNG C+ +     C+C    +EG  CE    +C L  C N G C+ +    +  C C + GF G  C   I  C    C  +G C+   +S  C CD  GF GD CE  I  C+ D C +GG C+       CVC   ++G++C+     C  G C  GG C      R    +P  + T  +Y                        +C    C++GG C  + N + C C +  +TG  C   +  C  N CKNG  CE     + C+C     S   +GG+ CD ++ G +   C +++                   PG++       T F         +   G +   K G                     L  Y  + ++++ ++LV G L A +     +  +    V+DGR++ + V+ DE
Sbjct:  144 CQDSVTTCSTQACQNGGTCVDVPDAGHQCQCVPG-YQGENCEENVDECWSEPCQNGAICKDGVNGYQCFCV-PGFQGSHCELDIKECASQPCQNNGTCLDEVDHYTCECAPG-FEGMNCEVEIDECELHPCQNGGICIDHIA--MYSCEC-TAGFQGQDCEVNIDECASMPCLNDGRCIDGINSYECDCDGTGFEGDHCEDNIQECASDPCQHGGTCLDGINQYKCVCWPGYEGENCQMDIDECEKGPCDNGGTCFQRSDVRNYKNLPELSVTTFSYGTAAGFICLCMAGFTGHNCSVNVDECESAPCQHGGRCQDLVNSYHCLCPD-GFTGVHCEEDINECASNPCKNGATCEDSVNSYKCHCPKAEGSQEPWGGQDCDVRLVGCLQHQCQHEKSCVPVLKDDGAHSYMCMCLPGWSGELCNTSTTFSFSSEGYIYLRLPGSKNRTKRGADDKRQRLHMQLRFRTTLPDMLLLYRGSMERFFTLELVQGSLQARVKSARVLQVSHPGPVNDGRWYDVTVAMDE 660          

HSP 2 Score: 80.8777 bits (198), Expect = 1.335e-14
Identity = 94/359 (26.18%), Postives = 139/359 (38.72%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRC-YNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGICQIVGNNRICNCTGTGFTGFDC--EISRCFNHKCQN-NGICILKQGIPECDCTKTVYEGQLCE--TPKCPLDFCLNNGHCL-LNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCE-KPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            C     +C  + C+N   C Y+  E    C     ++ G+ C+    +C    C N   Q   +  IC+C   G+TG  C  E+  C ++ C      C+       C C    + G+ C+     C    C N G C+ +        CV    G+ G  C + +  C    C     C    +   C+C  GF G  CE  I  C+   C N G C+       C CA  F+G +CE +   C +  C  GG C     M  C CT             +C    C N G C    N + C+C    + G+ C + +  C  + C++GG C     ++ C C   GY GE C   +D
Sbjct:   27 CTAAADRCLSSPCKNGATCLYHEGEYVCVCPNFPVKYTGKHCEELYDACSTTSCTNCTSQPGTDEFICHCP-DGYTGPSCEQEVDECHSNPCMGVRSYCVDGANSYACHC-PIGWAGENCQDSVTTCSTQACQNGGTCVDVPDAGHQCQCV---PGYQGENCEENVDECWSEPCQNGAICKDGVNGYQCFCVPGFQGSHCELDIKECASQPCQNNGTCLDEVDHYTCECAPGFEGMNCEVEIDECELHPCQNGGICIDHIAMYSCECTAGFQGQDCEVNIDECASMPCLNDGRCIDGINSYECDCDGTGFEGDHCEDNIQECASDPCQHGGTCLDGINQYKCVC-WPGYEGENCQMDID 379          

HSP 3 Score: 68.5514 bits (166), Expect = 7.313e-11
Identity = 97/387 (25.06%), Postives = 148/387 (38.24%), Query Frame = 1
Query: 1594 SEDWMTLLVNSNSIILAYSLPPNEGVHTIEMTRGGILIQDNTWHRVIINLNKPKEILYIHIDDVESLTNEIKLKNSKKELAEMNFISLSLGGISDNSQYTQFYNLLRKKNPEVSKLFSGPDELKFIGCLGDILVINSSYSGNLIQKPNVNSFPKESLFCR--------ACQENVKKCPKNYCQNKGRCYN-INETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCET--PKCPLDF---CLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPICSKDKCINGGKCV 2700
            SE +   L+NS+ ++    L    G   +  T     I D  WH + +++ +P + L        SLT +           +   +S  +GG           N L + N  +++        KF GCLG++ V      G  +   N+   P++S F R         CQ     C    C N+G C +  N+   +C   +  + GE C+ +   C  +PC  G C+ +  +  C+C   G+ G +CE  +  C    C N G C    G   C C    ++G+ C+   P    D    C N G C+         C C   GF G RC   I  C  N C     C  + +   C C  GF G  CE     +D   + G C 
Sbjct: 1069 SEVFCLGLLNSSLLV---KLDSGAGAPLLAFTSDRT-IADGAWHHIQLSMVEPAQSL-----SRWSLTVD----------GQRAGVSFGVGGN---------LNFLNESNIWLAE--------KFTGCLGEVRV-----GGVYLPLVNITDAPQQSQFTRLGGHEPILGCQ-GSPVCDSQPCLNQGVCQDHFNDFNCSC---RPGWEGEVCEAQTDECSSSPCLYGKCKDLLADYHCDCE-PGYKGKNCEEEVDNCLEFSCINGGRCEETVGTHSCSCPPG-FKGKRCQWRFPPVACDANTKCFNEGVCVGGDSGG--NCSCKP-GFSGARCEAEIDECSSNPCLNGATCQDQLNHFKCVCVPGFHGKFCENNRRVQDTSFHPGSCT 1405          

HSP 4 Score: 62.003 bits (149), Expect = 7.731e-9
Identity = 89/324 (27.47%), Postives = 120/324 (37.04%), Query Frame = 1
Query: 2188 GEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCTG--TGFTGFDCE--ISRCFNHKCQNNGICILKQGIPE--CDCTKTVYEGQLCE--TPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCL-VRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCE-KPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERC-TNKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKV 3111
            G  C      C  +PCKNG  C       +C C      +TG  CE     C    C N   C  + G  E  C C    Y G  CE    +C  + C+      ++  N    C C   G+ G  C   +  C    C   G C+ V D    C C  G+ G+ CE+ +  C  + C NG  C        C C   FQG  CE   K C    C   G C        C C           +  +C    C+NGGIC     ++ C C+   + G+ C  N   C    C N G C      + C+C  TG+ G+ C+  +
Sbjct:   24 GLLCTAAADRCLSSPCKNGATCLYHEGEYVCVCPNFPVKYTGKHCEELYDACSTTSCTN---CTSQPGTDEFICHCPDG-YTGPSCEQEVDECHSNPCMGVRSYCVDGANSYA-CHC-PIGWAGENCQDSVTTCSTQACQNGGTCVDVPDAGHQCQCVPGYQGENCEENVDECWSEPCQNGAICKDGVNGYQCFCVPGFQGSHCELDIKECASQPCQNNGTCLDEVDHYTCECAPGFEGMNCEVEIDECELHPCQNGGICIDHIAMYSCECT-AGFQGQDCEVNIDECASMPCLNDGRCIDGINSYECDCDGTGFEGDHCEDNI 340          
BLAST of notch-1 vs. Ensembl Medaka
Match: notch3 (neurogenic locus notch homolog protein 2 [Source:NCBI gene;Acc:101162450])

HSP 1 Score: 111.694 bits (278), Expect = 6.896e-24
Identity = 110/374 (29.41%), Postives = 160/374 (42.78%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRC-YNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKN-GICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLC--ETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRC--NKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGYCLY------GGKCRMVNGMPRCNCTQTNYMG-----------XXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            C E +  C  N C N   C +  +     C+C+   + G+ C+I    C  NPCKN G C       +C+C   GFTG  CE  I+ C  + C + G C        C C    + G  C  E  +C  + C N G C  + VN    C C   GF G  C  N P C ++ C   G C  + +   C C  GFTG  C+  +  C+   C+NGG C     S  C C K + G  C+     PV +C        GG+CR  +    C C +  + G               +     ++ C +GG C    N   C C    YTG  C ++V  C D  C+NG  C  + G + C+C + G+ G+ C+++++
Sbjct:  752 CAEVLTPCSPNPCANHAVCTHTADYLGYQCNCQPG-WQGQLCNIDVNECISNPCKNRGTCTNTLGGFVCSCRA-GFTGLTCETDINDCVPNPCLSGGSCTDGVNSYHCSCLPG-FTGSRCALEINECQSNPCKNGGTCT-DYVNSY-TCTCRP-GFTGIHCEINIPDCTESSCFNGGTCTDKINGYSCTCRSGFTGSHCQYEVNECNSQPCLNGGVCQDGLESFRCTCPKGYTGNRCQT----PVDWCRRSSPCQNGGRCRQNDASFTCEC-KNGWSGHYCDIPRVSCETAARQRGIQTDELCHHGGHCVNTGNTHFCKCP-ADYTGSYCESQVDHCEDKPCRNGATCRPYVGGYQCDC-MPGFMGQNCEREIN 1112          

HSP 2 Score: 110.923 bits (276), Expect = 1.243e-23
Identity = 121/379 (31.93%), Postives = 166/379 (43.80%), Query Frame = 1
Query: 2077 CQENVKKCPKNY-CQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGI-----------CQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFY----GYRCNKPICPQNY---CTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKC--INGGKCVVVDRSPFCVCAKDFQGKSCE-KPKPCPVGYCLYGGKCRMVNGMP---RCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKV--GCPDNYCKNGGAC--EIHRGKFGCNCSLTGYGGEQCDQK 3108
            CQ  V  C ++  CQN GRC   N+    C+CK   + G +CDI R SC+    + GI           C   GN   C C    +TG  CE  +  C +  C+N   C    G  +CDC    + GQ CE    +C    C N G C+    + +  C   + G         CN P+ P+N    C  NG C+ R     C C  GFTG++CE  I  C  + C   N   C+ +     CVC   F G+ C+ K   C    C  GG C + +  P    C C Q  Y+G  CE+   C E  C NGG C++ +    C+C    Y G +C ++   GC    C+NGG C  E     F C CS   + G++C+ K
Sbjct:  982 CQTPVDWCRRSSPCQNGGRCRQ-NDASFTCECKNG-WSGHYCDIPRVSCETAARQRGIQTDELCHHGGHCVNTGNTHFCKCPAD-YTGSYCESQVDHCEDKPCRNGATCRPYVGGYQCDCMPG-FMGQNCEREINECQSHPCQNGGTCIDLVGHYICSCPPGTLGVLCEINEDDCNTPVRPRNAPPKCLNNGTCVDRVGGYRCNCPPGFTGERCEGDINECLSNPCSPSNSFDCIQLPNDYQCVCKPGFTGRRCQNKFSVCESQPCQNGGACSVSSSSPLGYTCTC-QLGYIGPNCERSMSCRELSCYNGGSCTLTSRGARCSCL-PGYGGPQCQHRSTEGCSSKPCRNGGVCTEETSYPYFSCQCS-KDWAGKRCEHK 1353          

HSP 3 Score: 89.7373 bits (221), Expect = 3.875e-17
Identity = 105/359 (29.25%), Postives = 161/359 (44.85%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGICQIVGNNRICNCTGTGFTGFDC--EISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLC--ETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCN--KPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSC-EKPKPCPVGYCLYGGKCRMVNGMP--RCNCTQTNYMGXX-XXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            C+  + +C  N CQN G+C ++   K  C C+     G  C+I    C  NPC  GIC+   N   C C   GFTG  C  EI  C +  C+N G C+ ++    C C +  ++   C  +  +C    C++ G C    +N    C C   G+ G  C+  +  C  + C   G C+ + +   C C +GF G+ C+  I  C+ + C+N G CV    S  CVC   + G +C E   PC    C     C         +CNC Q  + G+       +C    C+N G C+     F+C+C    +TG  C   +  C  N C +GG+C      + C+C L G+ G +C  +++
Sbjct:  526 CENQLNECHSNPCQNSGKCVDL-VNKYICQCQHGT-SGTNCEINFDDCASNPCDYGICKDGINRYDCVCK-PGFTGPKCNVEIDECASSPCRNGGTCVDEENGFHCLCPEG-FKPPYCYSQVDECGSSPCVH-GSCR-EDINGY-RCDC-EPGWVGKNCDLDRNDCLPSPCQNAGTCIDKLNGFTCKCRQGFIGNLCQVNINECASNPCLNKGTCVDGVASFTCVCELPYSGPTCAEVLTPCSPNPCANHAVCTHTADYLGYQCNC-QPGWQGQLCNIDVNECISNPCKNRGTCTNTLGGFVCSC-RAGFTGLTCETDINDCVPNPCLSGGSCTDGVNSYHCSC-LPGFTGSRCALEIN 873          

HSP 4 Score: 82.8037 bits (203), Expect = 3.787e-15
Identity = 108/393 (27.48%), Postives = 150/393 (38.17%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYN-INETKIACDCKKTQFYGEFCDIKRPSCDPNPCKN-GICQIVGNNRICNCTGTGFTGFDCEIS--RCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPYCVCN-STGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCE---------------------------KP------------ICSKDKCINGGKCVVVDRSPFCVCAKDFQGKSC-EKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQ 3105
            C+ ++ +C    CQN   C + I E    C      + G +C      C+ NPC N G+C+   N   C C   GF+G  C+I    C +  CQN   C  +    EC C +  YEG LCE+    C  D C ++G C    ++ +    CN   G+ GYRC   +  C  N C  +G C+   +  +C C  G +G  CE                           KP             C+   C NGG CV  +    C+C + F+   C  +   C    C++G     +NG  RC+C               C    C+N G C    N F C C    + G  C   +  C  N C N G C      F C C L  Y G  C +
Sbjct:  375 CEIDINECLSMPCQNDATCLDRIGEFTCIC---MPGYTGTYCQTDIDDCESNPCVNDGVCRDTVNGFTCTCQ-PGFSGTMCQIDIDECASTPCQNGAKCHDRPNGFECRCAEG-YEGTLCESNINNCQPDPC-HHGTC----IDGIASYTCNCDPGYTGYRCENQLNECHSNPCQNSGKCVDLVNKYICQCQHGTSGTNCEINFDDCASNPCDYGICKDGINRYDCVCKPGFTGPKCNVEIDECASSPCRNGGTCVDEENGFHCLCPEGFKPPYCYSQVDECGSSPCVHGSCREDINGY-RCDCEPGWVGKNCDLDRNDCLPSPCQNAGTCIDKLNGFTCKCRQ-GFIGNLCQVNINECASNPCLNKGTCVDGVASFTCVCELP-YSGPTCAE 754          

HSP 5 Score: 74.3294 bits (181), Expect = 1.665e-12
Identity = 105/362 (29.01%), Postives = 144/362 (39.78%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFC--DIKRPSCDPNPCKNG-ICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCE-TPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI----CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKP-KPCPVGYCLYGGKCR-MVNGMPRCNCTQTNYMGXX-XXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKV-GCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            C++NV  CP + C N G C +   T   C C   ++ G++C  D+      PN C NG  C        C C   G+TG DC   I  C    C N   C  +     C+C      G LC     C  + C     C  N +N    C C   GF G  CN+ +       N C   G C+  + S  C C  G+ G +CE  I  C    C N   C+       C+C   + G  C+     C    C+  G CR  VNG   C C Q  + G        +C    C+NG  C    N F C C+   Y G  C + +  C  + C + G C      + CNC   GY G +C+ +++
Sbjct:  180 CEKNVDDCPGHKCMNGGLCVDGVNT-YNCQCPP-EWTGQYCAEDVNECLMQPNACHNGGTCFNTIGGHTCVCV-NGWTGDDCSENIDDCATAVCFNGATCHDRVASFFCEC-PVGKTGLLCHLDDACVSNPCNEGAVCDTNPLNGRAICTC-PAGFVGGACNQDMDECSIGANPCEHFGKCVNTEGSFQCQCGRGYAGPRCEIDINECLSMPCQNDATCLDRIGEFTCICMPGYTGTYCQTDIDDCESNPCVNDGVCRDTVNGF-TCTC-QPGFSGTMCQIDIDECASTPCQNGAKCHDRPNGFECRCAE-GYEGTLCESNINNCQPDPCHH-GTCIDGIASYTCNCD-PGYTGYRCENQLN 531          

HSP 6 Score: 73.559 bits (179), Expect = 2.644e-12
Identity = 105/367 (28.61%), Postives = 136/367 (37.06%), Query Frame = 1
Query: 2059 SLFCRACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSC-DPNPC-KNGICQIVGNNRICNCTGTGFTGFDCEISR--CFNHKCQNNGICILKQGIP-ECDCTKTVYEGQLCE--TPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFY-GYRCNKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRM--VNGMPRCNCTQTNYMGX--XXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            +L+ + C   +  C  + C N  RC N N+ +  C C    F G+ C      C  P  C  NG+C  +  +  C C   G++G  CE+    C   +C N G C        EC C    +EG  CE     CP   C+N G C+         C    TG Y     N+ +   N C   G C        C C  G+TGD C + I  C+   C NG  C     S FC C     G  C     C    C  G  C    +NG   C C      G   +           CE+ G C      F C C    Y G RC   +  C    C+N   C    G+F C C + GY G  C   +D
Sbjct:   59 TLWSQDCSR-IDACATSPCANGARCVNWND-QYNCSCPPG-FQGKNCHNDINECRKPGVCLNNGLCINMKGSFRCQCQ-PGYSGRICEVPTLPCAPSQCLNGGTCRQTSDHSYECACLPG-FEGHNCEKNVDDCPGHKCMNGGLCVDGVNTYNCQCPPEWTGQYCAEDVNECLMQPNACHNGGTCFNTIGGHTCVCVNGWTGDDCSENIDDCATAVCFNGATCHDRVASFFCECPVGKTGLLCHLDDACVSNPCNEGAVCDTNPLNGRAICTCPAGFVGGACNQDMDECSIGANPCEHFGKCVNTEGSFQCQCGR-GYAGPRCEIDINECLSMPCQNDATCLDRIGEFTCIC-MPGYTGTYCQTDID 418          

HSP 7 Score: 65.4698 bits (158), Expect = 7.564e-10
Identity = 72/242 (29.75%), Postives = 94/242 (38.84%), Query Frame = 1
Query: 2398 KTVYEGQLCETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQ-NYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKC-VVVDRSPFCVCAKDFQGKSCEKP-KPCPVGYCLYGGKCRMVNGMPRCNCT----QTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKV-GCPDNYCKNGGACEIHRGKFGCNCSLTGYG 3087
             T++         C    C N   C+    N    C C   GF G  C+  I  C +   C  NG C+    S  C C  G++G  CE P   C+  +C+NGG C    D S  C C   F+G +CEK    CP   C+ GG C  V+G+   NC      T     +           C NGG C        C C N  +TG+ C+  +  C    C NG  C      F C C +   G
Sbjct:   58 STLWSQDCSRIDACATSPCANGARCV--NWNDQYNCSC-PPGFQGKNCHNDINECRKPGVCLNNGLCINMKGSFRCQCQPGYSGRICEVPTLPCAPSQCLNGGTCRQTSDHSYECACLPGFEGHNCEKNVDDCPGHKCMNGGLC--VDGVNTYNCQCPPEWTGQYCAEDVNECLMQPNACHNGGTCFNTIGGHTCVCVN-GWTGDDCSENIDDCATAVCFNGATCHDRVASFFCECPVGKTG 293          
BLAST of notch-1 vs. Ensembl Medaka
Match: notch3 (neurogenic locus notch homolog protein 2 [Source:NCBI gene;Acc:101162450])

HSP 1 Score: 111.309 bits (277), Expect = 8.904e-24
Identity = 110/374 (29.41%), Postives = 160/374 (42.78%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRC-YNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKN-GICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLC--ETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRC--NKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGYCLY------GGKCRMVNGMPRCNCTQTNYMG-----------XXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            C E +  C  N C N   C +  +     C+C+   + G+ C+I    C  NPCKN G C       +C+C   GFTG  CE  I+ C  + C + G C        C C    + G  C  E  +C  + C N G C  + VN    C C   GF G  C  N P C ++ C   G C  + +   C C  GFTG  C+  +  C+   C+NGG C     S  C C K + G  C+     PV +C        GG+CR  +    C C +  + G               +     ++ C +GG C    N   C C    YTG  C ++V  C D  C+NG  C  + G + C+C + G+ G+ C+++++
Sbjct:  629 CAEVLTPCSPNPCANHAVCTHTADYLGYQCNCQPG-WQGQLCNIDVNECISNPCKNRGTCTNTLGGFVCSCRA-GFTGLTCETDINDCVPNPCLSGGSCTDGVNSYHCSCLPG-FTGSRCALEINECQSNPCKNGGTCT-DYVNSY-TCTCRP-GFTGIHCEINIPDCTESSCFNGGTCTDKINGYSCTCRSGFTGSHCQYEVNECNSQPCLNGGVCQDGLESFRCTCPKGYTGNRCQT----PVDWCRRSSPCQNGGRCRQNDASFTCEC-KNGWSGHYCDIPRVSCETAARQRGIQTDELCHHGGHCVNTGNTHFCKCP-ADYTGSYCESQVDHCEDKPCRNGATCRPYVGGYQCDC-MPGFMGQNCEREIN 989          

HSP 2 Score: 110.538 bits (275), Expect = 1.513e-23
Identity = 121/379 (31.93%), Postives = 166/379 (43.80%), Query Frame = 1
Query: 2077 CQENVKKCPKNY-CQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGI-----------CQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFY----GYRCNKPICPQNY---CTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKC--INGGKCVVVDRSPFCVCAKDFQGKSCE-KPKPCPVGYCLYGGKCRMVNGMP---RCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKV--GCPDNYCKNGGAC--EIHRGKFGCNCSLTGYGGEQCDQK 3108
            CQ  V  C ++  CQN GRC   N+    C+CK   + G +CDI R SC+    + GI           C   GN   C C    +TG  CE  +  C +  C+N   C    G  +CDC    + GQ CE    +C    C N G C+    + +  C   + G         CN P+ P+N    C  NG C+ R     C C  GFTG++CE  I  C  + C   N   C+ +     CVC   F G+ C+ K   C    C  GG C + +  P    C C Q  Y+G  CE+   C E  C NGG C++ +    C+C    Y G +C ++   GC    C+NGG C  E     F C CS   + G++C+ K
Sbjct:  859 CQTPVDWCRRSSPCQNGGRCRQ-NDASFTCECKNG-WSGHYCDIPRVSCETAARQRGIQTDELCHHGGHCVNTGNTHFCKCPAD-YTGSYCESQVDHCEDKPCRNGATCRPYVGGYQCDCMPG-FMGQNCEREINECQSHPCQNGGTCIDLVGHYICSCPPGTLGVLCEINEDDCNTPVRPRNAPPKCLNNGTCVDRVGGYRCNCPPGFTGERCEGDINECLSNPCSPSNSFDCIQLPNDYQCVCKPGFTGRRCQNKFSVCESQPCQNGGACSVSSSSPLGYTCTC-QLGYIGPNCERSMSCRELSCYNGGSCTLTSRGARCSCL-PGYGGPQCQHRSTEGCSSKPCRNGGVCTEETSYPYFSCQCS-KDWAGKRCEHK 1230          

HSP 3 Score: 89.3521 bits (220), Expect = 5.021e-17
Identity = 105/359 (29.25%), Postives = 161/359 (44.85%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGICQIVGNNRICNCTGTGFTGFDC--EISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLC--ETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCN--KPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSC-EKPKPCPVGYCLYGGKCRMVNGMP--RCNCTQTNYMGXX-XXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            C+  + +C  N CQN G+C ++   K  C C+     G  C+I    C  NPC  GIC+   N   C C   GFTG  C  EI  C +  C+N G C+ ++    C C +  ++   C  +  +C    C++ G C    +N    C C   G+ G  C+  +  C  + C   G C+ + +   C C +GF G+ C+  I  C+ + C+N G CV    S  CVC   + G +C E   PC    C     C         +CNC Q  + G+       +C    C+N G C+     F+C+C    +TG  C   +  C  N C +GG+C      + C+C L G+ G +C  +++
Sbjct:  403 CENQLNECHSNPCQNSGKCVDL-VNKYICQCQHGT-SGTNCEINFDDCASNPCDYGICKDGINRYDCVCK-PGFTGPKCNVEIDECASSPCRNGGTCVDEENGFHCLCPEG-FKPPYCYSQVDECGSSPCVH-GSCR-EDINGY-RCDC-EPGWVGKNCDLDRNDCLPSPCQNAGTCIDKLNGFTCKCRQGFIGNLCQVNINECASNPCLNKGTCVDGVASFTCVCELPYSGPTCAEVLTPCSPNPCANHAVCTHTADYLGYQCNC-QPGWQGQLCNIDVNECISNPCKNRGTCTNTLGGFVCSC-RAGFTGLTCETDINDCVPNPCLSGGSCTDGVNSYHCSC-LPGFTGSRCALEIN 750          

HSP 4 Score: 82.8037 bits (203), Expect = 4.186e-15
Identity = 108/393 (27.48%), Postives = 150/393 (38.17%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYN-INETKIACDCKKTQFYGEFCDIKRPSCDPNPCKN-GICQIVGNNRICNCTGTGFTGFDCEIS--RCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPYCVCN-STGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCE---------------------------KP------------ICSKDKCINGGKCVVVDRSPFCVCAKDFQGKSC-EKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQ 3105
            C+ ++ +C    CQN   C + I E    C      + G +C      C+ NPC N G+C+   N   C C   GF+G  C+I    C +  CQN   C  +    EC C +  YEG LCE+    C  D C ++G C    ++ +    CN   G+ GYRC   +  C  N C  +G C+   +  +C C  G +G  CE                           KP             C+   C NGG CV  +    C+C + F+   C  +   C    C++G     +NG  RC+C               C    C+N G C    N F C C    + G  C   +  C  N C N G C      F C C L  Y G  C +
Sbjct:  252 CEIDINECLSMPCQNDATCLDRIGEFTCIC---MPGYTGTYCQTDIDDCESNPCVNDGVCRDTVNGFTCTCQ-PGFSGTMCQIDIDECASTPCQNGAKCHDRPNGFECRCAEG-YEGTLCESNINNCQPDPC-HHGTC----IDGIASYTCNCDPGYTGYRCENQLNECHSNPCQNSGKCVDLVNKYICQCQHGTSGTNCEINFDDCASNPCDYGICKDGINRYDCVCKPGFTGPKCNVEIDECASSPCRNGGTCVDEENGFHCLCPEGFKPPYCYSQVDECGSSPCVHGSCREDINGY-RCDCEPGWVGKNCDLDRNDCLPSPCQNAGTCIDKLNGFTCKCRQ-GFIGNLCQVNINECASNPCLNKGTCVDGVASFTCVCELP-YSGPTCAE 631          

HSP 5 Score: 73.9442 bits (180), Expect = 1.938e-12
Identity = 105/362 (29.01%), Postives = 144/362 (39.78%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFC--DIKRPSCDPNPCKN-GICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCE-TPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI----CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKP-KPCPVGYCLYGGKCR-MVNGMPRCNCTQTNYMGXX-XXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKV-GCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            C++NV  CP + C N G C +   T   C C   ++ G++C  D+      PN C N G C        C C   G+TG DC   I  C    C N   C  +     C+C      G LC     C  + C     C  N +N    C C   GF G  CN+ +       N C   G C+  + S  C C  G+ G +CE  I  C    C N   C+       C+C   + G  C+     C    C+  G CR  VNG   C C Q  + G        +C    C+NG  C    N F C C+   Y G  C + +  C  + C + G C      + CNC   GY G +C+ +++
Sbjct:   57 CEKNVDDCPGHKCMNGGLCVDGVNT-YNCQCPP-EWTGQYCAEDVNECLMQPNACHNGGTCFNTIGGHTCVCV-NGWTGDDCSENIDDCATAVCFNGATCHDRVASFFCEC-PVGKTGLLCHLDDACVSNPCNEGAVCDTNPLNGRAICTC-PAGFVGGACNQDMDECSIGANPCEHFGKCVNTEGSFQCQCGRGYAGPRCEIDINECLSMPCQNDATCLDRIGEFTCICMPGYTGTYCQTDIDDCESNPCVNDGVCRDTVNGF-TCTC-QPGFSGTMCQIDIDECASTPCQNGAKCHDRPNGFECRCAE-GYEGTLCESNINNCQPDPCHH-GTCIDGIASYTCNCD-PGYTGYRCENQLN 408          

HSP 6 Score: 65.4698 bits (158), Expect = 8.452e-10
Identity = 86/322 (26.71%), Postives = 110/322 (34.16%), Query Frame = 1
Query: 2182 FYGEFCDIKRPSCDPNPCKNG-IC-QIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRM--VNGMPRCNCTQTNYMGX--XXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVD 3114
            + G  C++    C P+ C NG  C Q   ++  C C   GF G +CE  +  C  HKC N G+C+       C C    + GQ C           +   CL+                            N C   G C        C C  G+TGD C + I  C+   C NG  C     S FC C     G  C     C    C  G  C    +NG   C C      G   +           CE+ G C      F C C    Y G RC   +  C    C+N   C    G+F C C + GY G  C   +D
Sbjct:   13 YSGRICEVPTLPCAPSQCLNGGTCRQTSDHSYECACL-PGFEGHNCEKNVDDCPGHKCMNGGLCVDGVNTYNCQCPPE-WTGQYCAE---------DVNECLMQP--------------------------NACHNGGTCFNTIGGHTCVCVNGWTGDDCSENIDDCATAVCFNGATCHDRVASFFCECPVGKTGLLCHLDDACVSNPCNEGAVCDTNPLNGRAICTCPAGFVGGACNQDMDECSIGANPCEHFGKCVNTEGSFQCQCGR-GYAGPRCEIDINECLSMPCQNDATCLDRIGEFTCIC-MPGYTGTYCQTDID 295          

HSP 7 Score: 58.151 bits (139), Expect = 1.164e-7
Identity = 53/167 (31.74%), Postives = 69/167 (41.32%), Query Frame = 1
Query: 2614 CYCDEGFTGDKCEKPI--CSKDKCINGGKC-VVVDRSPFCVCAKDFQGKSCEK-PKPCPVGYCLYGGKCRMVNGMPRCNCT----QTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKV-GCPDNYCKNGGACEIHRGKFGCNCSLTGYG 3087
            C C  G++G  CE P   C+  +C+NGG C    D S  C C   F+G +CEK    CP   C+ GG C  V+G+   NC      T     +           C NGG C        C C N  +TG+ C+  +  C    C NG  C      F C C +   G
Sbjct:    7 CQCQPGYSGRICEVPTLPCAPSQCLNGGTCRQTSDHSYECACLPGFEGHNCEKNVDDCPGHKCMNGGLC--VDGVNTYNCQCPPEWTGQYCAEDVNECLMQPNACHNGGTCFNTIGGHTCVCVN-GWTGDDCSENIDDCATAVCFNGATCHDRVASFFCECPVGKTG 170          
BLAST of notch-1 vs. Ensembl Medaka
Match: ENSORLT00000015846.2 (protein crumbs homolog 2 [Source:NCBI gene;Acc:101156666])

HSP 1 Score: 100.523 bits (249), Expect = 1.593e-20
Identity = 139/513 (27.10%), Postives = 200/513 (38.99%), Query Frame = 1
Query: 2071 RACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCK-NGICQIVGNNRICNCTGTGFTGFDC--EISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCE--TPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCT-NKVGCPDNYCKNGGACEIHRGKFGCNCSLTG-----YGGEQCDQKV-------------------DGV-----MCD---YKEPGYAITAFKPPMVSSGIV-----------------------TSMGFQTFVKTGTLFCYETADDKYWLIKLVNGRLVADINGISFNMKT----VVSDGRYHFLKVSRDETNFVISL 3402
            + C+E+V +C    CQN   C +    +  C C    F G  C+I    C   PC+ N  C    ++  C+C   GF G +C  EI  C +H CQN  IC    G+  C+C    ++G  CE    +C  + C N   C  + VN    C C+ TGF G  C   I  C  + C     C+       C C  G+ G  CE  I  C +  C N G+C   +RS       D++    E       GY      C    G    NC+             +C  + C+NGG C    N + C C  V + GE+C  N   C    C+NGG+CE  R  F C+C         +GG++CD K+                   DGV     +C    Y E     T F     SSG +                         + FQT +    LF +    + Y L+++VNG + A    +   ++     VV+DG++  + V  D    V+ L
Sbjct:  179 KTCEEDVNECSSEPCQNGAICID-GVAEFHCFCVPG-FQGHNCEIDINECASQPCENNATCINDKDHYECDCL-LGFAGVNCETEIDECESHPCQNGAICHDLFGMYSCECMPG-FDGTDCEVDVDECASEPCQNGAFC-RDMVNSYE-CDCSDTGFEGDHCQVDILECASDPCQHGATCVEGIKGYTCMCWPGYEGHNCEVDIDECIEHPCENDGEC--FERSDLSHWELDWKFSFAEA-----AGY-----ICHCQPGFTGENCS---------INIDECESEPCQNGGFCQDKVNGYSCACP-VGFLGEQCEINFNECESQPCQNGGSCEDGRASFTCHCPEADPGEYPWGGDRCDVKLYGCINHECQNGATCLPWLEDGVHGHRCLCPHGFYDETCSTKTTFS--FSSSGFIHLQVDLEGRTRRSLKHNAGQRFGVQLRFQTTLPNMLLF-FRGNVNNYLLLEIVNGGIHAKAFSLEAELEITYPGVVNDGQWRDVHVFWDGEGLVLIL 660          

HSP 2 Score: 79.7221 bits (195), Expect = 3.217e-14
Identity = 98/371 (26.42%), Postives = 133/371 (35.85%), Query Frame = 1
Query: 2077 CQENVKKCPKNYCQNKGRCYN-INETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGI---------------------------------------CQIVGNNRICNCTGTGFTGFDC--EISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETP--KCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCE-KPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXX-XXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGAC 3036
            C    +KC    CQN   C + +N+    C     Q+ G+ CD    +C   PC + I                                       C    N   C C   G+ G DC   ++ C +  C+NNG C+LK    EC C    +EG+ CE    +C  + C N   C+        +CV    GF G+ C   I  C    C  N  C+   D   C C  GF G  CE  I  C    C NG  C  +     C C   F G  CE     C    C  G  CR +     C+C+ T + G        +C    C++G  C      + C C    Y G  C   +  C ++ C+N G C
Sbjct:   26 CTATSEKCLSAPCQNGATCVDTMNDYACICAKGGVQYMGKNCDELYEACTFAPCLDCISTPGETEYQCVCPEGLTGVNCTEDVDECHSSPCSEPQTLCVDQLNGYFCRCP-PGYGGLDCRTRVTDCIDEPCRNNGTCVLKPNGFECHCAPG-FEGKTCEEDVNECSSEPCQNGAICIDGVAEFHCFCV---PGFQGHNCEIDINECASQPCENNATCINDKDHYECDCLLGFAGVNCETEIDECESHPCQNGAICHDLFGMYSCECMPGFDGTDCEVDVDECASEPCQNGAFCRDMVNSYECDCSDTGFEGDHCQVDILECASDPCQHGATCVEGIKGYTCMCW-PGYEGHNCEVDIDECIEHPCENDGEC 390          

HSP 3 Score: 77.7962 bits (190), Expect = 1.419e-13
Identity = 91/336 (27.08%), Postives = 136/336 (40.48%), Query Frame = 1
Query: 2185 YGEFCDIKRPSCDPNPCKNG-ICQIVGNNRICNCT--GTGFTGFDCE----------ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKC--PLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCE-KPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXY-CENGGICSIINNVFICNCSNVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVDGVMC 3126
            +G  C      C   PC+NG  C    N+  C C   G  + G +C+             C +   +    C+  +G+   +CT+ V E   C +  C  P   C++       Q+N   +C C   G+ G  C   +  C    C  NG C+++ +   C+C  GF G  CE+ +  CS + C NG  C+       C C   FQG +CE     C    C     C        C+C    + G  CE      E + C+NG IC  +  ++ C C    + G  C   V  C    C+NG  C      + C+CS TG+ G+ C  +VD + C
Sbjct:   22 WGTLCTATSEKCLSAPCQNGATCVDTMNDYACICAKGGVQYMGKNCDELYEACTFAPCLDCISTPGETEYQCVCPEGLTGVNCTEDVDE---CHSSPCSEPQTLCVD-------QLNGY-FCRC-PPGYGGLDCRTRVTDCIDEPCRNNGTCVLKPNGFECHCAPGFEGKTCEEDVNECSSEPCQNGAICIDGVAEFHCFCVPGFQGHNCEIDINECASQPCENNATCINDKDHYECDCL-LGFAGVNCETEIDECESHPCQNGAICHDLFGMYSCECM-PGFDGTDCEVDVDECASEPCQNGAFCRDMVNSYECDCSDTGFEGDHC--QVDILEC 341          

HSP 4 Score: 72.4034 bits (176), Expect = 4.855e-12
Identity = 97/410 (23.66%), Postives = 158/410 (38.54%), Query Frame = 1
Query: 1507 PLTNEGIILFIEFKTKFDGII-----WHA----VNVFSSEDWMTLLVNSNSIILAYSLPPNEGVHTIEMTRGGILIQDNTWHRVIINLNKPKEILYIHIDDVESLTNEIKLKNSKKELAEMNFISLSLGGISDNSQYTQFYNLLRKKNPEVSKLFSGPDELKFIGCLGDILVINSSYS-GNLIQKPNVNSF-----PKESLFCRACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGICQIVGNNRICNCTGTGFTGFDCE--ISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCPLD-----FCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPIC 2664
            P++N    +++E +T+    +     W +    V V  S  W+ + +++ +  L +              +G   + D  WHRV +++ + K  +   I  V+ +T+   + +    +                         L K   +VS   S      F GCLG + +        + I+ P  + F     PK  L C +       C  N C N   C ++   K  C C  + + G  C+     C   PC +G C+       C+C   G+TG  C+  I  C +H C++ G C        C C+K  Y G  C+    P+       C+N+G C  N       C C   GF G RC   +  C  N C   G+CL R +  VC C  G++G  C+  +C
Sbjct: 1047 PISN----IYMELRTRSQNAVVLKATWGSDLLMVGVLDSVVWVEIHIDNKAESLTF--------------KGIRQVADGLWHRVNVSMVERKRRVSPWIIIVDGITDASSVPHRTGSIG-----------------------FLNKDRAKVSIAES------FTGCLGAVRLGGVYLPFRDDIKAPQQSQFYLLGKPKVQLGCTS----APVCDSNPCLNGATCEDLF-NKFGCLCD-SGWEGVKCETDADECGSQPCVHGSCKDYLAGYECHCD-PGYTGRICDENIDECEDHACEHGGTCQDGINAYSCLCSKD-YSGPRCQWTFPPIQCNTDVQCINDGVC--NDGLWGANCTCKP-GFTGSRCELEMDECESNPCQNGGSCLDRFNMFVCKCPSGYSGPVCDDHVC 1398          

HSP 5 Score: 56.9954 bits (136), Expect = 2.735e-7
Identity = 67/236 (28.39%), Postives = 100/236 (42.37%), Query Frame = 1
Query: 2428 TPKCPLDFCLNNGHC--LLNQVNQLPYCVCNSTGFYGYRCNKPI--CPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPI--CSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCS-NVSYTGERCTNKVG-CPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKV 3111
             P C  + CLN   C  L N+      C+C+S G+ G +C      C    C  +G+C        C+CD G+TG  C++ I  C    C +GG C     +  C+C+KD+ G  C+   P P+                +CN                  +  C N G+C+  + ++  NC+    +TG RC  ++  C  N C+NGG+C      F C C  +GY G  CD  V
Sbjct: 1205 APVCDSNPCLNGATCEDLFNKFG----CLCDS-GWEGVKCETDADECGSQPCV-HGSCKDYLAGYECHCDPGYTGRICDENIDECEDHACEHGGTCQDGINAYSCLCSKDYSGPRCQWTFP-PI----------------QCN-----------------TDVQCINDGVCN--DGLWGANCTCKPGFTGSRCELEMDECESNPCQNGGSCLDRFNMFVCKCP-SGYSGPVCDDHV 1397          
BLAST of notch-1 vs. Planmine SMEST
Match: SMESG000056635.1 (SMESG000056635.1)

HSP 1 Score: 3850.83 bits (9985), Expect = 0.000e+0
Identity = 1979/1994 (99.25%), Postives = 1986/1994 (99.60%), Query Frame = 1
Query:   55 MWKILGILLICQSQLSKSQISPIEEVILTSQPIPVSFTMPDAMLRLHPWNFAKYSSIELEFHTREPRGILFFVGSSTASTDSIGLEIFNSNVYAFGKLLGKDFRIKLNPDNIRVSNGKFFKVAIQILATNYLVLKFDDVEIKEKIPTPGKLEFNSYTYIGGVDTITRLPWKAFSQTGFTGCINYIRINGERFLDTKQHSKQTEMQGAKTGVCQTSTARCLPGICGPGKCHERSYNMLDQSKNFYCDCSGTFKSYAYSAVDILRGEPCLIDSQRFQCNTKSYLLYTFDKEKTTHYDDISIDFQTTNTKEPLFLMKSGTANVINTFLSAEVLAGQVIIIIKXXXXXXXXXXXXXXXXXXXXXDGQWHTLKLSRFAYNVEFYVDEQETISRGELYQSSLEEKFFNKVKEILLGSTTKPPGPDKCTGEIKNFFWNEEDLLGRKNKYGYYSSQLVTEKXXXXXXXXXXXXXXXXCTLKPNHIYTVLNNIPLTNEGIILFIEFKTKFDGIIWHAVNVFSSEDWMTLLVNSNSIILAYSLPPNEGVHTIEMTRGGILIQDNTWHRVIINLNKPKEILYIHIDDVESLTNEIKLKNSKKELAEMNFISLSLGGISDNSQYTQFYNLLRKKNPEVSKLFSGPDELKFIGCLGDILVINSSYSGNLIQKPNVNSFPKESLFCRACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGICQIVGNNRICNCTGTGFTGFDCEISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPICSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVDGVMCDYKEPGYAITAFKPPMVSSGIVTSMGFQTFVKTGTLFCYETADDKYWLIKLVNGRLVADINGISFNMKTVVSDGRYHFLKVSRDETNFVISLDHFPFENLLIPTAITSILTLPNNIIIYTKLTLCNSCPDTFNRDRFQGAIGSAKSGHVDISKGLKXXXXXXXXXXXXXXXXXLTPVMPLPEIPTIQPCYAGFCKNSGKCLVKNYGPRCDCGISGFTGNQCDQKIMVIKSVPPNPGYVIITRNPVIATNFDLIRFISESSESSTPLTALITPEGNSIEIKIENQKVFVRINGEAKGPLNDKLIEKNVPNFFKLVNLLGRVTVYVNGTKLGHIVLKEPLIMKNNSIQISKVLVGANRNADETIKGSLGDFRYNELNLISSNGTFDPNSKQIPNIKLEQWKMIGRKMPDINKVRKGSHGGVVFTSTKFIIADGFGAGDVVSISNGPIVLGAQLLGAKTIGVDPFXXXXXXXXXXXXXXXXWAFMNLIFSRTHVTASGNKLLLIENNDLQISPLLQEKASIQLISGGFQADTNETMIHTMRQNRMDMNKTSDFFTSNGFNKSTFGTTGSADFEKIQPVKYASIFAQQDTDLQQPNVFSEEEMKIDCCVMSNNSRYAITGSVAGPPQVWDLNDGFLTHIMDGANQACTSLHLAMNNSVLIGLVTQNQQPFSLKLLMMWKFPDGQIIDSGYEYMCTTCCVSADGECVILADDMKDSSITILNLTNQQTRKLVYKAGLVNGDGIQLLKQTKNGQFLIAGFQTFDNSTSYMVFDMTMQSRKNGVFKINANTNCTDFINNNEAVTGTESGELIIWDLNTVQAVRRILISPNFVDNSESRNPHKDSLTCVTVSNDGSLLATTGLDATVKVWNMEDEKLLYNLNKHKDEIQSLVWSNDNEMLVSGSLDGSIRIWNVTNGQEMCGFNSNIEITXXXXXXXXXXXXGLGERAGVNKLVMLKILRNIHQVSRDIKDELVSQLL 6036
            MWKILGILLICQSQLSKSQISPIEE ILTSQPIPVSFTMP AMLRLHPWNFAKYSSIELEFHTREPRGILFFVGSSTASTDSIGLEIFNSNVYAFGKLLGKDFRIKLNPDNIRVSNGKFFKVAIQILATNYLVLKFDDVEIKEKIPTPGKLEFNSYTYIGGVDTITRLPWKAFSQTGFTGCINYIRINGERFLDTKQHSKQTEMQGAKTGVCQTSTARCLPGICGPGKCHERSYNMLDQSKNFYCDCSGTFKSYAYSAVDILRGEPCLIDSQRFQCNTKSYLLYTFDKEKTTHYDDISIDFQTTNTKEPLFLMKSGTANVINTFLSAEVLAGQVIIIIKLYESNNENYKSSFFSKNSNLNDGQWHTLKLSRFAYNVEFYVDEQE +SRGELYQSSLEEKFFN+VKEILLGSTTKPPGPDKCTGEIKNFFWNEEDLLGRKNKYGYYSSQLVTEKPTLPILPPFPRQPPMPCTLKPNHIYTVLNNIPLTNEGIILFIEFKTKFDGIIWHAVNVFSSEDWMTLLVNSNSIILAYSLPPNEGVHTIEMTRGGILIQDNTWHRVIINLNKPKEIL+IHIDDVESLTNEIKLKNSKKELAEMNFISLSLGGISDNSQYTQFYNLLR KNPEVSKLFSGPDELKFIGCLG+ILVINSSYSGNLIQKPNVNSFPKESLFCRACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGICQIVGNNRICNCTGTGFTGFDCEISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPICSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGKKCEKPKKCPEKYCENGGICSIINNVFICNCSNVSYTGERCTNKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVDGVMCDYKEPGYAITAFKPPMVSSGIVTSMGFQTFVKTGTLFCYETADDKYWLIKLVNGRLVADINGISFNMKTVVSDGRYHFLKVSRDETNFVISLDH+PFENLLIPTAITSILTLPNNIIIYTKLTLCNSCPDTFNRDRFQGAIGSAKSGHVDISKGLKNDG+AGGGIMIGGITNILTPVMPLPEIPTIQPCYAGFCKNSGKCLVKNYGPRCDCGISGFTGNQCDQKIM IKSVPPNPGYVIITRNPVIATNFDLIRFISESSESSTPLTALITPEGNSIEIKIENQKVFVRINGEAKGPLNDKLIEKNVPNFFKLVNLLGRVTVYVNGTKLGHIVLKEPLIMKNNSIQISKVLVGANRNADETIKGSLGDFRYNELNLISSNGTFDPNSKQIPNIKLEQWKMIGRKMPDINKVRKGSHGGVVFTSTKFIIADGFGAGDVVSISNGPIVLGAQLLGAKTIGVDPFILGIILACILLIIALIWAFMNLIFSRTHVTASGNKLLLIENNDLQISPLLQEKASIQL+SGGFQADTNETMIHTMRQNRMDMNKTSDFFTSNGFNKSTFGTTGSADFEKIQPVKYASIFAQQDTDLQQPNVFSE EMKIDCCVMSNNSRYAITGSVAGPPQVWDLNDGFLTHIMDGANQACTSLHLAMNNSVLIGLVTQNQQPFSLKLLMMWKFPDGQIIDSG EYMCTTCCVSADGECVILADDMKDSSITILNLTNQQTRKLVYKAGLVNGDGIQLLKQTKNGQFLIAGFQTFDNSTSYMVFDMTMQSRKNGVFKINANTNCTDFINNNE VTGTESGELIIWDLNTVQAVRRILISPNFVDNSESRNPHKDSLTCVTVSNDGSLLATTGLDATVKVWNMEDEKLLYNLNKHKDEIQSLVWSNDNEMLVSGSLDGSIRIWNVTNGQEMCGFNSNIEITKVLLSDDKKVVVGLGERAGVNKLVMLKILRNIHQVSRDIKDELVSQLL
Sbjct:    1 MWKILGILLICQSQLSKSQISPIEEFILTSQPIPVSFTMPGAMLRLHPWNFAKYSSIELEFHTREPRGILFFVGSSTASTDSIGLEIFNSNVYAFGKLLGKDFRIKLNPDNIRVSNGKFFKVAIQILATNYLVLKFDDVEIKEKIPTPGKLEFNSYTYIGGVDTITRLPWKAFSQTGFTGCINYIRINGERFLDTKQHSKQTEMQGAKTGVCQTSTARCLPGICGPGKCHERSYNMLDQSKNFYCDCSGTFKSYAYSAVDILRGEPCLIDSQRFQCNTKSYLLYTFDKEKTTHYDDISIDFQTTNTKEPLFLMKSGTANVINTFLSAEVLAGQVIIIIKLYESNNENYKSSFFSKNSNLNDGQWHTLKLSRFAYNVEFYVDEQENLSRGELYQSSLEEKFFNRVKEILLGSTTKPPGPDKCTGEIKNFFWNEEDLLGRKNKYGYYSSQLVTEKPTLPILPPFPRQPPMPCTLKPNHIYTVLNNIPLTNEGIILFIEFKTKFDGIIWHAVNVFSSEDWMTLLVNSNSIILAYSLPPNEGVHTIEMTRGGILIQDNTWHRVIINLNKPKEILHIHIDDVESLTNEIKLKNSKKELAEMNFISLSLGGISDNSQYTQFYNLLRNKNPEVSKLFSGPDELKFIGCLGEILVINSSYSGNLIQKPNVNSFPKESLFCRACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKNGICQIVGNNRICNCTGTGFTGFDCEISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPICSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGKKCEKPKKCPEKYCENGGICSIINNVFICNCSNVSYTGERCTNKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVDGVMCDYKEPGYAITAFKPPMVSSGIVTSMGFQTFVKTGTLFCYETADDKYWLIKLVNGRLVADINGISFNMKTVVSDGRYHFLKVSRDETNFVISLDHYPFENLLIPTAITSILTLPNNIIIYTKLTLCNSCPDTFNRDRFQGAIGSAKSGHVDISKGLKNDGSAGGGIMIGGITNILTPVMPLPEIPTIQPCYAGFCKNSGKCLVKNYGPRCDCGISGFTGNQCDQKIMAIKSVPPNPGYVIITRNPVIATNFDLIRFISESSESSTPLTALITPEGNSIEIKIENQKVFVRINGEAKGPLNDKLIEKNVPNFFKLVNLLGRVTVYVNGTKLGHIVLKEPLIMKNNSIQISKVLVGANRNADETIKGSLGDFRYNELNLISSNGTFDPNSKQIPNIKLEQWKMIGRKMPDINKVRKGSHGGVVFTSTKFIIADGFGAGDVVSISNGPIVLGAQLLGAKTIGVDPFILGIILACILLIIALIWAFMNLIFSRTHVTASGNKLLLIENNDLQISPLLQEKASIQLLSGGFQADTNETMIHTMRQNRMDMNKTSDFFTSNGFNKSTFGTTGSADFEKIQPVKYASIFAQQDTDLQQPNVFSEGEMKIDCCVMSNNSRYAITGSVAGPPQVWDLNDGFLTHIMDGANQACTSLHLAMNNSVLIGLVTQNQQPFSLKLLMMWKFPDGQIIDSGDEYMCTTCCVSADGECVILADDMKDSSITILNLTNQQTRKLVYKAGLVNGDGIQLLKQTKNGQFLIAGFQTFDNSTSYMVFDMTMQSRKNGVFKINANTNCTDFINNNEVVTGTESGELIIWDLNTVQAVRRILISPNFVDNSESRNPHKDSLTCVTVSNDGSLLATTGLDATVKVWNMEDEKLLYNLNKHKDEIQSLVWSNDNEMLVSGSLDGSIRIWNVTNGQEMCGFNSNIEITKVLLSDDKKVVVGLGERAGVNKLVMLKILRNIHQVSRDIKDELVSQLL 1994          
BLAST of notch-1 vs. Planmine SMEST
Match: SMESG000027800.1 (SMESG000027800.1)

HSP 1 Score: 789.645 bits (2038), Expect = 0.000e+0
Identity = 487/1485 (32.79%), Postives = 795/1485 (53.54%), Query Frame = 1
Query:  127 EVILTSQPIPVSFTMPDAMLRLHPWNFAKYSSIELEFHTREPRGILFFVGSSTASTDSIGLEIFNSNVY-AFGKLLGKDFRIKLNPDNIRVSNGKFFKVAIQILATNYLVLKFDDVEIKEKIPTPGKLEFNSYTYIGGVDTITRLPWKAFSQTGFTGCINYIRINGERFLDTKQHSKQT--EMQGAKTGVCQTSTARCLPGICGPGKCHERSYNMLDQSKNFYCDCSGTFKSYAYSAVDILRGEPCLIDSQRFQCNTKSYLLYTF------DKEKTTHYDDISIDFQTTNTKEPLFLMKSGTANVINTFLSAEVLAGQVIIIIKXXXXXXXXXXXXXXXXXXXXXDGQWHTLKLSRFAYNVEFYVDEQETISRGELYQSSLEEKFFNKVKEILLGSTTKPPGPDKCTGEIKNFFWNEEDLLGRKNKYGYYSSQLVTEKXXXXXXXXXXXXXXXXCTLKPNHIYTVLNNIPLTNEGIILFIEFKTKFDGIIWHAVNVFSS-EDWMTLLVNSNSIILAYSLPPNEGVHTIEMTRGGILIQDNTWHRVIINLNKPKEILYIHIDD--VESLTNEIKLKNSKKELAEMNFISLSLGGISDNSQYTQFYNLLRKKNPEVSKLFSGPDELKFIGCLGDILVINSSYSGNLIQKPNVNSFPKESLFCRACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKN-GICQIVGNNRICNCTGTGFTGFDCEISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPICSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVDGVMCDYKEPGYAITAFKPPMVSSGIVTSMGFQTFVKTGTLFCYETADDKYWLIKLVNGRLVADINGISFNMKTVVSDGRYHFLKVSRDETNFVISLDHFPFENLLIPTAITSILTLPNNIIIYTKLTLCNSCPDTFNRDRFQGAIGSAKSGHVDISKGLKXXXXXXXXXXXXXXXXXLTPVMPLPEIPTIQP--CYAGFCKNSGKCLVKNYGPRCDCGISGFTGNQCDQKIMVIKSVPPNPGYVIITRNPVIATNFDLIRFISESSESSTPLTALITPEGNSIEIKIENQKVFVRINGEAKGPLND-KLIEKNVPNFFKLVNLLGRVTVYVNGTKLGHIVLKEPLIMKNNSIQISKVLVGANRNADETIKGSLGDFRYNELNLISSNGTF--DPNSKQ------IPNI--KLEQWKMIGRKMPDINKVRKGSHGGVVFTSTK-FIIADGFGAGDVVSISNGPIVLGA-QLLGAKTI 4497
            + ++++ P+P +FT  D ++R  PW+F ++ SIE++F T+EPRG+L FVG   A TD + LE ++ N+Y AFG + GKD+R ++NP    V+ G F  + I+    +    KF++VE+     +  + EF SYTYIGG+D  +RLPW  +S+ GF GCINY+R+N ++++D +  + Q   ++ G   G C      C    C  G CH+RSY  L   KNFYCDCS   ++Y     +I R E C  +S+    +  S+ +  F      DK   TH DDI+I F+T      +F      +++   + S +++ G V++   + + +    K +F     NLND +WH + + R A ++  YVD       G++        F N  + I +GS     G +K  G I+NF+WN+ D LG +   G Y   + T KP+LP LPP+PR PP+ CT++P+H YT + +I  T + + ++IEFKT++ GIIWH  ++++S  ++MTL++  N +IL + +   + V+ IE       + DN WHRV+I LNK    + +H+D      + N   +K+      +++ +    GG+ ++  +T  +  LR   P +++  + P+    +GCLG+ L+    +  N +    +N++P  SL C  C+ N  KC   YCQN+G CY +   K+ C+C +  F GE C+    +C  + C+N G C +      C+C+GTGF G +CE S C +  CQNNGIC ++ G+P CDC  T ++G++CE P C   FC N G C ++  N+ P C C +TGF G +C + IC  N+C   G C+ RD    C C   FTG +C +  CS + C N G C + +  P C C K+F+G+ CE  K CP  +C YGG C++ NG P C+C  TNY G +C  PK+CP ++C NGG C + N  + C C    + G RC  +  CP N+CKN G C +    F C+C+ TGY G  C +KV G+  +Y++ GY I    PP+ ++    ++GFQTF+KTGT++ + T D +YW +K+ NG+LV DING  +  ++ V+DG+Y+ + + ++    +  L     E  LI  +   + +   N I Y ++ +  S  +   RD F+GAIG        I + +K       G            ++ +P I    P  C  GFC N+G+C++ +Y P C C  +GF+          +K+V     Y+   +  ++ T+ D  +F+ ++  S+ P+      +    EI + + K+    NG+    ++D + ++   P   K +    ++  ++NG +     LK  +I  + S+   K+++GA+++     +G++G F +N   +I  +G      N K       +PN+  K+   K + + +PD+  V  G+HGG++    + ++   G G G +V +  GP++LGA  LLG   I
Sbjct:  455 DYLISATPVPFTFTEFDKLVRFSPWDFEQFESIEIQFRTKEPRGVLLFVGPDNAHTDYVCLEFYDRNLYLAFG-IDGKDYRKQMNPKGTFVTTGNFHTIFIKRDRNHKFTAKFENVEVDIGDQSGHQREFGSYTYIGGIDNPSRLPWYVWSREGFVGCINYMRVNEDKYIDPRGKNNQYSGDIAGVDIGKCLNDVRHCTASHCEGGTCHDRSYPYL-SDKNFYCDCSAISRTYRNPVGNIEREEICARESEEITSDGTSFYVVDFKSEDSRDKMMKTHTDDIAISFKTLQPDATIFQTFRSNSDL---YFSVKLVGGYVVVETNINDKDKFGSKQTFRVPVGNLNDNKWHNIYIKRRAEHILIYVDNVNNQIIGKIPVLKYLRTFDNTFEYIFVGSDNFEAGKEKFVGSIRNFYWNQFDFLGTRRLAGTYKGTIKTPKPSLPPLPPYPRDPPVKCTMRPDHRYTKVTDIAATQDEVGIYIEFKTRYSGIIWHGYDMYNSGRNYMTLMLIDNKLILVHHINEVKSVNIIE-DGSQFQLDDNNWHRVVIMLNKKLRRIIVHVDKGYQPKVINLAVVKS-----IDISKLEFYFGGMPED-LFTNVFTQLRVSLPYLAEKVATPNTWSLVGCLGEFLISEDKFLSNKLSGA-INTYPLNSLDCGGCR-NPLKCEMGYCQNRGLCYQLAIDKLGCNCSEG-FTGEKCEKIEFTCPRDFCRNGGRCYMYDKQPKCDCSGTGFRGNNCEQSFCSDSFCQNNGICSIENGLPVCDCRNTQHKGKVCEKPICSESFCNNRGRCYVH--NEQPICDCTATGFIGQKCEREICTSNFCKNGGLCVPRDSQPTCQCTPEFTGFQCNERKCSSNFCFNDGTCYISNERPQCSCTKNFEGQRCEIEKRCPSDFCYYGGVCQIRNGYPYCDCQNTNYEGTRCNIPKRCPLEFCSNGGNCQVRNGQYYCECQE-GFQGSRCQERKECPPNFCKNDGICSVINNGFICDCTHTGYFGISCSEKVTGLKNEYEKYGYVIYPVSPPVGTTSDQVTVGFQTFMKTGTIYTFRTTDGRYWSLKMDNGKLVIDINGNKYQTQSNVNDGQYYVVSIKKEGERGIFKLLGPQTETFLI--SFDGVTSGVQNEISYKEIIIGASNEE---RDIFKGAIGGFNWNGKYIFEQIKTGQGERKGT---------IEIILVPTIINRPPTSCPKGFCANNGECIIMDYIPYCKCENTGFSDKD-------VKNV-----YMEFFQWRIVMTHKDETQFLLQAYTSNNPVIRFELNDEQFYEINMIDGKLIFLENGKFPRLISDGQRMDNENPYLVKFIREKEKIKFFINGIQTSSFNLKN-IISNDGSLIHKKIILGADKSYKTYFQGAIGGFEWNGYKMIDDSGNLLNSVNKKGEVIIILMPNLTRKIILPKKV-KPLPDL--VPAGNHGGIIMRPNELYVPGVGSGGGAIVPVGVGPVILGAGSLLGLPVI 1891          

HSP 2 Score: 318.931 bits (816), Expect = 4.318e-87
Identity = 187/487 (38.40%), Postives = 279/487 (57.29%), Query Frame = 1
Query: 4597 VTASGNKLLLIENNDLQISPLLQEKASI-QLISGGFQADTNETMI----HTMRQNRMDMNKT---SDFFTSNGFNKS-TFGTTGSADFEKIQPVKYASIFAQQDTDLQ-QPNVFSEEEMKIDCCVMSNNSRYAITGSVAGPPQVWDLNDGFLTHIMDGANQACTSLHLAMNNSVLIGLV-----TQNQQPFSLKLLMMWKFPDGQIIDSGYEYMCTTCCVSADGECVILADDMKDSSITILNL---TNQQTRKLVYKA-GLVNGDGIQLLKQTKNGQFLIAGFQTFDNSTSYMVFDMTMQSRKNGVF------KINANTNCTDFINNNEAVTGTESGELIIWDLNTVQAVRRILISPNFVDNSESR-NPHKDSLTCVTVSNDGSLLATTGLDATVKVWNMEDEKLLYNLNKHKDEIQSLVWSNDNEMLVSGSLDGSIRIWNVTNGQEMCGFNSNIEITXXXXXXXXXXXXGLGERAGVNKLVMLKIL 5979
            ++A+ N +   ++ D   + + +E+ +I + I G  Q+     ++    H MR  R          ++   N  + S  FGT G     +I            +TD + +PNVF+ EEMK+DCCV+S NSRYA+TGS   PPQ+WD+  G L  +MDG    CT LHLA  + +L+GLV     T+      LK L MW F  G  I    + MC+  C++   + +++  +  D S++I+      NQ  +++ Y+    +N +GI  LK + N + ++AGF   D+   YMVFD+ M S  NG+         NA T  T+ I  +EA+TGT  GELIIW+L T + VR+ILIS     N++++ NPHKD++ C+ VS +G  L T   D TV V+ M DE+L++ L  H D++ S V S DNE++VSGS DGS+R+WN+ +G +MC F SNIEI  V L++DKK +V LGER G+ KL+ML+I+
Sbjct: 1998 LSANANGMAHGDHGDFHSTTIREERGNITRNIGGSMQSLPGGPLLYSGTHNMRSTRSVAGGAPYGHNYGHGNMLDVSDRFGTIGQGSIMRIDT-------THHETDFEGRPNVFAGEEMKVDCCVLSQNSRYAVTGSANSPPQIWDMQTGELFKVMDGMEIGCTDLHLACGDKILVGLVMDEMPTEASDHHRLKRLQMWDFATGSQIAMPLDVMCSASCITHSSDHMVINREYPDGSMSIVCWDLQANQPVQEIHYQTPDFMNHEGITFLKISHNDRMVVAGFTGMDDQAHYMVFDL-MASYPNGIMVQPLISSFNAKTCATEIIGADEAITGTRKGELIIWNLRTAKPVRQILISATLEGNTQTKLNPHKDAINCIAVSKNGEFLVTGSADQTVNVYTMADERLMHTLEGHADDVLSAVISLDNEIIVSGSWDGSMRVWNLESGSQMCWFTSNIEILSVKLTNDKKAIVALGERMGLRKLIMLQII 2476          
BLAST of notch-1 vs. Planmine SMEST
Match: SMESG000027800.1 (SMESG000027800.1)

HSP 1 Score: 789.26 bits (2037), Expect = 0.000e+0
Identity = 487/1485 (32.79%), Postives = 795/1485 (53.54%), Query Frame = 1
Query:  127 EVILTSQPIPVSFTMPDAMLRLHPWNFAKYSSIELEFHTREPRGILFFVGSSTASTDSIGLEIFNSNVY-AFGKLLGKDFRIKLNPDNIRVSNGKFFKVAIQILATNYLVLKFDDVEIKEKIPTPGKLEFNSYTYIGGVDTITRLPWKAFSQTGFTGCINYIRINGERFLDTKQHSKQT--EMQGAKTGVCQTSTARCLPGICGPGKCHERSYNMLDQSKNFYCDCSGTFKSYAYSAVDILRGEPCLIDSQRFQCNTKSYLLYTF------DKEKTTHYDDISIDFQTTNTKEPLFLMKSGTANVINTFLSAEVLAGQVIIIIKXXXXXXXXXXXXXXXXXXXXXDGQWHTLKLSRFAYNVEFYVDEQETISRGELYQSSLEEKFFNKVKEILLGSTTKPPGPDKCTGEIKNFFWNEEDLLGRKNKYGYYSSQLVTEKXXXXXXXXXXXXXXXXCTLKPNHIYTVLNNIPLTNEGIILFIEFKTKFDGIIWHAVNVFSS-EDWMTLLVNSNSIILAYSLPPNEGVHTIEMTRGGILIQDNTWHRVIINLNKPKEILYIHIDD--VESLTNEIKLKNSKKELAEMNFISLSLGGISDNSQYTQFYNLLRKKNPEVSKLFSGPDELKFIGCLGDILVINSSYSGNLIQKPNVNSFPKESLFCRACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKN-GICQIVGNNRICNCTGTGFTGFDCEISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPICSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVDGVMCDYKEPGYAITAFKPPMVSSGIVTSMGFQTFVKTGTLFCYETADDKYWLIKLVNGRLVADINGISFNMKTVVSDGRYHFLKVSRDETNFVISLDHFPFENLLIPTAITSILTLPNNIIIYTKLTLCNSCPDTFNRDRFQGAIGSAKSGHVDISKGLKXXXXXXXXXXXXXXXXXLTPVMPLPEIPTIQP--CYAGFCKNSGKCLVKNYGPRCDCGISGFTGNQCDQKIMVIKSVPPNPGYVIITRNPVIATNFDLIRFISESSESSTPLTALITPEGNSIEIKIENQKVFVRINGEAKGPLND-KLIEKNVPNFFKLVNLLGRVTVYVNGTKLGHIVLKEPLIMKNNSIQISKVLVGANRNADETIKGSLGDFRYNELNLISSNGTF--DPNSKQ------IPNI--KLEQWKMIGRKMPDINKVRKGSHGGVVFTSTK-FIIADGFGAGDVVSISNGPIVLGA-QLLGAKTI 4497
            + ++++ P+P +FT  D ++R  PW+F ++ SIE++F T+EPRG+L FVG   A TD + LE ++ N+Y AFG + GKD+R ++NP    V+ G F  + I+    +    KF++VE+     +  + EF SYTYIGG+D  +RLPW  +S+ GF GCINY+R+N ++++D +  + Q   ++ G   G C      C    C  G CH+RSY  L   KNFYCDCS   ++Y     +I R E C  +S+    +  S+ +  F      DK   TH DDI+I F+T      +F      +++   + S +++ G V++   + + +    K +F     NLND +WH + + R A ++  YVD       G++        F N  + I +GS     G +K  G I+NF+WN+ D LG +   G Y   + T KP+LP LPP+PR PP+ CT++P+H YT + +I  T + + ++IEFKT++ GIIWH  ++++S  ++MTL++  N +IL + +   + V+ IE       + DN WHRV+I LNK    + +H+D      + N   +K+      +++ +    GG+ ++  +T  +  LR   P +++  + P+    +GCLG+ L+    +  N +    +N++P  SL C  C+ N  KC   YCQN+G CY +   K+ C+C +  F GE C+    +C  + C+N G C +      C+C+GTGF G +CE S C +  CQNNGIC ++ G+P CDC  T ++G++CE P C   FC N G C ++  N+ P C C +TGF G +C + IC  N+C   G C+ RD    C C   FTG +C +  CS + C N G C + +  P C C K+F+G+ CE  K CP  +C YGG C++ NG P C+C  TNY G +C  PK+CP ++C NGG C + N  + C C    + G RC  +  CP N+CKN G C +    F C+C+ TGY G  C +KV G+  +Y++ GY I    PP+ ++    ++GFQTF+KTGT++ + T D +YW +K+ NG+LV DING  +  ++ V+DG+Y+ + + ++    +  L     E  LI  +   + +   N I Y ++ +  S  +   RD F+GAIG        I + +K       G            ++ +P I    P  C  GFC N+G+C++ +Y P C C  +GF+          +K+V     Y+   +  ++ T+ D  +F+ ++  S+ P+      +    EI + + K+    NG+    ++D + ++   P   K +    ++  ++NG +     LK  +I  + S+   K+++GA+++     +G++G F +N   +I  +G      N K       +PN+  K+   K + + +PD+  V  G+HGG++    + ++   G G G +V +  GP++LGA  LLG   I
Sbjct:  461 DYLISATPVPFTFTEFDKLVRFSPWDFEQFESIEIQFRTKEPRGVLLFVGPDNAHTDYVCLEFYDRNLYLAFG-IDGKDYRKQMNPKGTFVTTGNFHTIFIKRDRNHKFTAKFENVEVDIGDQSGHQREFGSYTYIGGIDNPSRLPWYVWSREGFVGCINYMRVNEDKYIDPRGKNNQYSGDIAGVDIGKCLNDVRHCTASHCEGGTCHDRSYPYL-SDKNFYCDCSAISRTYRNPVGNIEREEICARESEEITSDGTSFYVVDFKSEDSRDKMMKTHTDDIAISFKTLQPDATIFQTFRSNSDL---YFSVKLVGGYVVVETNINDKDKFGSKQTFRVPVGNLNDNKWHNIYIKRRAEHILIYVDNVNNQIIGKIPVLKYLRTFDNTFEYIFVGSDNFEAGKEKFVGSIRNFYWNQFDFLGTRRLAGTYKGTIKTPKPSLPPLPPYPRDPPVKCTMRPDHRYTKVTDIAATQDEVGIYIEFKTRYSGIIWHGYDMYNSGRNYMTLMLIDNKLILVHHINEVKSVNIIE-DGSQFQLDDNNWHRVVIMLNKKLRRIIVHVDKGYQPKVINLAVVKS-----IDISKLEFYFGGMPED-LFTNVFTQLRVSLPYLAEKVATPNTWSLVGCLGEFLISEDKFLSNKLSGA-INTYPLNSLDCGGCR-NPLKCEMGYCQNRGLCYQLAIDKLGCNCSEG-FTGEKCEKIEFTCPRDFCRNGGRCYMYDKQPKCDCSGTGFRGNNCEQSFCSDSFCQNNGICSIENGLPVCDCRNTQHKGKVCEKPICSESFCNNRGRCYVH--NEQPICDCTATGFIGQKCEREICTSNFCKNGGLCVPRDSQPTCQCTPEFTGFQCNERKCSSNFCFNDGTCYISNERPQCSCTKNFEGQRCEIEKRCPSDFCYYGGVCQIRNGYPYCDCQNTNYEGTRCNIPKRCPLEFCSNGGNCQVRNGQYYCECQE-GFQGSRCQERKECPPNFCKNDGICSVINNGFICDCTHTGYFGISCSEKVTGLKNEYEKYGYVIYPVSPPVGTTSDQVTVGFQTFMKTGTIYTFRTTDGRYWSLKMDNGKLVIDINGNKYQTQSNVNDGQYYVVSIKKEGERGIFKLLGPQTETFLI--SFDGVTSGVQNEISYKEIIIGASNEE---RDIFKGAIGGFNWNGKYIFEQIKTGQGERKGT---------IEIILVPTIINRPPTSCPKGFCANNGECIIMDYIPYCKCENTGFSDKD-------VKNV-----YMEFFQWRIVMTHKDETQFLLQAYTSNNPVIRFELNDEQFYEINMIDGKLIFLENGKFPRLISDGQRMDNENPYLVKFIREKEKIKFFINGIQTSSFNLKN-IISNDGSLIHKKIILGADKSYKTYFQGAIGGFEWNGYKMIDDSGNLLNSVNKKGEVIIILMPNLTRKIILPKKV-KPLPDL--VPAGNHGGIIMRPNELYVPGVGSGGGAIVPVGVGPVILGAGSLLGLPVI 1897          

HSP 2 Score: 318.546 bits (815), Expect = 4.717e-87
Identity = 187/487 (38.40%), Postives = 279/487 (57.29%), Query Frame = 1
Query: 4597 VTASGNKLLLIENNDLQISPLLQEKASI-QLISGGFQADTNETMI----HTMRQNRMDMNKT---SDFFTSNGFNKS-TFGTTGSADFEKIQPVKYASIFAQQDTDLQ-QPNVFSEEEMKIDCCVMSNNSRYAITGSVAGPPQVWDLNDGFLTHIMDGANQACTSLHLAMNNSVLIGLV-----TQNQQPFSLKLLMMWKFPDGQIIDSGYEYMCTTCCVSADGECVILADDMKDSSITILNL---TNQQTRKLVYKA-GLVNGDGIQLLKQTKNGQFLIAGFQTFDNSTSYMVFDMTMQSRKNGVF------KINANTNCTDFINNNEAVTGTESGELIIWDLNTVQAVRRILISPNFVDNSESR-NPHKDSLTCVTVSNDGSLLATTGLDATVKVWNMEDEKLLYNLNKHKDEIQSLVWSNDNEMLVSGSLDGSIRIWNVTNGQEMCGFNSNIEITXXXXXXXXXXXXGLGERAGVNKLVMLKIL 5979
            ++A+ N +   ++ D   + + +E+ +I + I G  Q+     ++    H MR  R          ++   N  + S  FGT G     +I            +TD + +PNVF+ EEMK+DCCV+S NSRYA+TGS   PPQ+WD+  G L  +MDG    CT LHLA  + +L+GLV     T+      LK L MW F  G  I    + MC+  C++   + +++  +  D S++I+      NQ  +++ Y+    +N +GI  LK + N + ++AGF   D+   YMVFD+ M S  NG+         NA T  T+ I  +EA+TGT  GELIIW+L T + VR+ILIS     N++++ NPHKD++ C+ VS +G  L T   D TV V+ M DE+L++ L  H D++ S V S DNE++VSGS DGS+R+WN+ +G +MC F SNIEI  V L++DKK +V LGER G+ KL+ML+I+
Sbjct: 2004 LSANANGMAHGDHGDFHSTTIREERGNITRNIGGSMQSLPGGPLLYSGTHNMRSTRSVAGGAPYGHNYGHGNMLDVSDRFGTIGQGSIMRIDT-------THHETDFEGRPNVFAGEEMKVDCCVLSQNSRYAVTGSANSPPQIWDMQTGELFKVMDGMEIGCTDLHLACGDKILVGLVMDEMPTEASDHHRLKRLQMWDFATGSQIAMPLDVMCSASCITHSSDHMVINREYPDGSMSIVCWDLQANQPVQEIHYQTPDFMNHEGITFLKISHNDRMVVAGFTGMDDQAHYMVFDL-MASYPNGIMVQPLISSFNAKTCATEIIGADEAITGTRKGELIIWNLRTAKPVRQILISATLEGNTQTKLNPHKDAINCIAVSKNGEFLVTGSADQTVNVYTMADERLMHTLEGHADDVLSAVISLDNEIIVSGSWDGSMRVWNLESGSQMCWFTSNIEILSVKLTNDKKAIVALGERMGLRKLIMLQII 2482          
BLAST of notch-1 vs. Planmine SMEST
Match: SMESG000027800.1 (SMESG000027800.1)

HSP 1 Score: 783.482 bits (2022), Expect = 0.000e+0
Identity = 487/1485 (32.79%), Postives = 794/1485 (53.47%), Query Frame = 1
Query:  127 EVILTSQPIPVSFTMPDAMLRLHPWNFAKYSSIELEFHTREPRGILFFVGSSTASTDSIGLEIFNSNVY-AFGKLLGKDFRIKLNPDNIRVSNGKFFKVAIQILATNYLVLKFDDVEIKEKIPTPGKLEFNSYTYIGGVDTITRLPWKAFSQTGFTGCINYIRINGERFLDTKQHSKQT--EMQGAKTGVCQTSTARCLPGICGPGKCHERSYNMLDQSKNFYCDCSGTFKSYAYSAVDILRGEPCLIDSQRFQCNTKSYLLYTF------DKEKTTHYDDISIDFQTTNTKEPLFLMKSGTANVINTFLSAEVLAGQVIIIIKXXXXXXXXXXXXXXXXXXXXXDGQWHTLKLSRFAYNVEFYVDEQETISRGELYQSSLEEKFFNKVKEILLGSTTKPPGPDKCTGEIKNFFWNEEDLLGRKNKYGYYSSQLVTEKXXXXXXXXXXXXXXXXCTLKPNHIYTVLNNIPLTNEGIILFIEFKTKFDGIIWHAVNVFSS-EDWMTLLVNSNSIILAYSLPPNEGVHTIEMTRGGILIQDNTWHRVIINLNKPKEILYIHIDD--VESLTNEIKLKNSKKELAEMNFISLSLGGISDNSQYTQFYNLLRKKNPEVSKLFSGPDELKFIGCLGDILVINSSYSGNLIQKPNVNSFPKESLFCRACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKN-GICQIVGNNRICNCTGTGFTGFDCEISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPICSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVDGVMCDYKEPGYAITAFKPPMVSSGIVTSMGFQTFVKTGTLFCYETADDKYWLIKLVNGRLVADINGISFNMKTVVSDGRYHFLKVSRDETNFVISLDHFPFENLLIPTAITSILTLPNNIIIYTKLTLCNSCPDTFNRDRFQGAIGSAKSGHVDISKGLKXXXXXXXXXXXXXXXXXLTPVMPLPEIPTIQP--CYAGFCKNSGKCLVKNYGPRCDCGISGFTGNQCDQKIMVIKSVPPNPGYVIITRNPVIATNFDLIRFISESSESSTPLTALITPEGNSIEIKIENQKVFVRINGEAKGPLND-KLIEKNVPNFFKLVNLLGRVTVYVNGTKLGHIVLKEPLIMKNNSIQISKVLVGANRNADETIKGSLGDFRYNELNLISSNGTF--DPNSKQ------IPNI--KLEQWKMIGRKMPDINKVRKGSHGGVVFTSTK-FIIADGFGAGDVVSISNGPIVLGA-QLLGAKTI 4497
            + ++++ P+P +FT  D ++R  PW+F ++ SIE++F T+EPRG+L FVG   A TD + LE ++ N+Y AFG + GKD+R ++NP    V+ G F  + I+    +    KF++VE+     +  + EF SYTYIGG+D  +RLPW  +S+ GF GCINY+R+N ++++D +  + Q   ++ G   G C      C    C  G CH+RSY  L   KNFYCDCS   ++Y     +I R E C  +S+    +  S+ +  F      DK   TH DDI+I F+T      +F      +++   + S +++ G V++   + + +    K +F     NLND +WH + + R A ++  YVD       G++        F N  + I +GS     G +K  G I+NF+WN+ D LG +   G Y   + T KP+LP LPP+PR PP+ CT++P+H YT + +I  T + + ++IEFKT++ GIIWH  ++++S  ++MTL++  N +IL + +   + V+ IE       + DN WHRV+I LNK    + +H+D      + N   +K+      +++ +    GG+ ++  +T  +  LR   P +++  + P+    +GCLG+ L+    +  N +    +N++P  SL C  C+ N  KC   YCQN+G CY +   K+ C+C +  F GE C+    +C  + C+N G C +      C+C+GTGF G +CE S C +  CQNNGIC ++ G+P CDC  T ++G++CE P C   FC N G C ++  N+ P C C +TGF G +C + IC  N+C   G C+ RD    C C   FTG +C +  CS + C N G C + +  P C C K+F+G+ CE  K CP  +C YGG C++ NG P C+C  TNY G +C  PK+CP ++C NGG C + N  + C C    + G RC  +  CP N+CKN G C +    F C+C+ TGY G  C +KV G+  +Y++ GY I    PP+ ++    ++GFQTF+KTGT++ + T D +YW +K+ NG+LV DING  +  ++ V+DG+Y+ + + ++    +  L     E  LI  +   + +   N I Y ++ +  S  +   RD F+GAIG        I + +K       G            ++ +P I    P  C  GFC N+G+C++ +Y P C C  +GF+          +K+V     Y+   +  +  T+ D  +F+ ++  S+ P+      +    EI + + K+    NG+    ++D + ++   P   K +    ++  ++NG +     LK  +I  + S+   K+++GA+++     +G++G F +N   +I  +G      N K       +PN+  K+   K + + +PD+  V  G+HGG++    + ++   G G G +V +  GP++LGA  LLG   I
Sbjct:  455 DYLISATPVPFTFTEFDKLVRFSPWDFEQFESIEIQFRTKEPRGVLLFVGPDNAHTDYVCLEFYDRNLYLAFG-IDGKDYRKQMNPKGTFVTTGNFHTIFIKRDRNHKFTAKFENVEVDIGDQSGHQREFGSYTYIGGIDNPSRLPWYVWSREGFVGCINYMRVNEDKYIDPRGKNNQYSGDIAGVDIGKCLNDVRHCTASHCEGGTCHDRSYPYL-SDKNFYCDCSAISRTYRNPVGNIEREEICARESEEITSDGTSFYVVDFKSEDSRDKMMKTHTDDIAISFKTLQPDATIFQTFRSNSDL---YFSVKLVGGYVVVETNINDKDKFGSKQTFRVPVGNLNDNKWHNIYIKRRAEHILIYVDNVNNQIIGKIPVLKYLRTFDNTFEYIFVGSDNFEAGKEKFVGSIRNFYWNQFDFLGTRRLAGTYKGTIKTPKPSLPPLPPYPRDPPVKCTMRPDHRYTKVTDIAATQDEVGIYIEFKTRYSGIIWHGYDMYNSGRNYMTLMLIDNKLILVHHINEVKSVNIIE-DGSQFQLDDNNWHRVVIMLNKKLRRIIVHVDKGYQPKVINLAVVKS-----IDISKLEFYFGGMPED-LFTNVFTQLRVSLPYLAEKVATPNTWSLVGCLGEFLISEDKFLSNKLSGA-INTYPLNSLDCGGCR-NPLKCEMGYCQNRGLCYQLAIDKLGCNCSEG-FTGEKCEKIEFTCPRDFCRNGGRCYMYDKQPKCDCSGTGFRGNNCEQSFCSDSFCQNNGICSIENGLPVCDCRNTQHKGKVCEKPICSESFCNNRGRCYVH--NEQPICDCTATGFIGQKCEREICTSNFCKNGGLCVPRDSQPTCQCTPEFTGFQCNERKCSSNFCFNDGTCYISNERPQCSCTKNFEGQRCEIEKRCPSDFCYYGGVCQIRNGYPYCDCQNTNYEGTRCNIPKRCPLEFCSNGGNCQVRNGQYYCECQE-GFQGSRCQERKECPPNFCKNDGICSVINNGFICDCTHTGYFGISCSEKVTGLKNEYEKYGYVIYPVSPPVGTTSDQVTVGFQTFMKTGTIYTFRTTDGRYWSLKMDNGKLVIDINGNKYQTQSNVNDGQYYVVSIKKEGERGIFKLLGPQTETFLI--SFDGVTSGVQNEISYKEIIIGASNEE---RDIFKGAIGGFNWNGKYIFEQIKTGQGERKGT---------IEIILVPTIINRPPTSCPKGFCANNGECIIMDYIPYCKCENTGFSDKD-------VKNV-----YMEFFQWRI--THKDETQFLLQAYTSNNPVIRFELNDEQFYEINMIDGKLIFLENGKFPRLISDGQRMDNENPYLVKFIREKEKIKFFINGIQTSSFNLKN-IISNDGSLIHKKIILGADKSYKTYFQGAIGGFEWNGYKMIDDSGNLLNSVNKKGEVIIILMPNLTRKIILPKKV-KPLPDL--VPAGNHGGIIMRPNELYVPGVGSGGGAIVPVGVGPVILGAGSLLGLPVI 1889          

HSP 2 Score: 318.931 bits (816), Expect = 4.387e-87
Identity = 187/487 (38.40%), Postives = 279/487 (57.29%), Query Frame = 1
Query: 4597 VTASGNKLLLIENNDLQISPLLQEKASI-QLISGGFQADTNETMI----HTMRQNRMDMNKT---SDFFTSNGFNKS-TFGTTGSADFEKIQPVKYASIFAQQDTDLQ-QPNVFSEEEMKIDCCVMSNNSRYAITGSVAGPPQVWDLNDGFLTHIMDGANQACTSLHLAMNNSVLIGLV-----TQNQQPFSLKLLMMWKFPDGQIIDSGYEYMCTTCCVSADGECVILADDMKDSSITILNL---TNQQTRKLVYKA-GLVNGDGIQLLKQTKNGQFLIAGFQTFDNSTSYMVFDMTMQSRKNGVF------KINANTNCTDFINNNEAVTGTESGELIIWDLNTVQAVRRILISPNFVDNSESR-NPHKDSLTCVTVSNDGSLLATTGLDATVKVWNMEDEKLLYNLNKHKDEIQSLVWSNDNEMLVSGSLDGSIRIWNVTNGQEMCGFNSNIEITXXXXXXXXXXXXGLGERAGVNKLVMLKIL 5979
            ++A+ N +   ++ D   + + +E+ +I + I G  Q+     ++    H MR  R          ++   N  + S  FGT G     +I            +TD + +PNVF+ EEMK+DCCV+S NSRYA+TGS   PPQ+WD+  G L  +MDG    CT LHLA  + +L+GLV     T+      LK L MW F  G  I    + MC+  C++   + +++  +  D S++I+      NQ  +++ Y+    +N +GI  LK + N + ++AGF   D+   YMVFD+ M S  NG+         NA T  T+ I  +EA+TGT  GELIIW+L T + VR+ILIS     N++++ NPHKD++ C+ VS +G  L T   D TV V+ M DE+L++ L  H D++ S V S DNE++VSGS DGS+R+WN+ +G +MC F SNIEI  V L++DKK +V LGER G+ KL+ML+I+
Sbjct: 1996 LSANANGMAHGDHGDFHSTTIREERGNITRNIGGSMQSLPGGPLLYSGTHNMRSTRSVAGGAPYGHNYGHGNMLDVSDRFGTIGQGSIMRIDT-------THHETDFEGRPNVFAGEEMKVDCCVLSQNSRYAVTGSANSPPQIWDMQTGELFKVMDGMEIGCTDLHLACGDKILVGLVMDEMPTEASDHHRLKRLQMWDFATGSQIAMPLDVMCSASCITHSSDHMVINREYPDGSMSIVCWDLQANQPVQEIHYQTPDFMNHEGITFLKISHNDRMVVAGFTGMDDQAHYMVFDL-MASYPNGIMVQPLISSFNAKTCATEIIGADEAITGTRKGELIIWNLRTAKPVRQILISATLEGNTQTKLNPHKDAINCIAVSKNGEFLVTGSADQTVNVYTMADERLMHTLEGHADDVLSAVISLDNEIIVSGSWDGSMRVWNLESGSQMCWFTSNIEILSVKLTNDKKAIVALGERMGLRKLIMLQII 2474          
BLAST of notch-1 vs. Planmine SMEST
Match: SMESG000027800.1 (SMESG000027800.1)

HSP 1 Score: 783.482 bits (2022), Expect = 0.000e+0
Identity = 487/1485 (32.79%), Postives = 794/1485 (53.47%), Query Frame = 1
Query:  127 EVILTSQPIPVSFTMPDAMLRLHPWNFAKYSSIELEFHTREPRGILFFVGSSTASTDSIGLEIFNSNVY-AFGKLLGKDFRIKLNPDNIRVSNGKFFKVAIQILATNYLVLKFDDVEIKEKIPTPGKLEFNSYTYIGGVDTITRLPWKAFSQTGFTGCINYIRINGERFLDTKQHSKQT--EMQGAKTGVCQTSTARCLPGICGPGKCHERSYNMLDQSKNFYCDCSGTFKSYAYSAVDILRGEPCLIDSQRFQCNTKSYLLYTF------DKEKTTHYDDISIDFQTTNTKEPLFLMKSGTANVINTFLSAEVLAGQVIIIIKXXXXXXXXXXXXXXXXXXXXXDGQWHTLKLSRFAYNVEFYVDEQETISRGELYQSSLEEKFFNKVKEILLGSTTKPPGPDKCTGEIKNFFWNEEDLLGRKNKYGYYSSQLVTEKXXXXXXXXXXXXXXXXCTLKPNHIYTVLNNIPLTNEGIILFIEFKTKFDGIIWHAVNVFSS-EDWMTLLVNSNSIILAYSLPPNEGVHTIEMTRGGILIQDNTWHRVIINLNKPKEILYIHIDD--VESLTNEIKLKNSKKELAEMNFISLSLGGISDNSQYTQFYNLLRKKNPEVSKLFSGPDELKFIGCLGDILVINSSYSGNLIQKPNVNSFPKESLFCRACQENVKKCPKNYCQNKGRCYNINETKIACDCKKTQFYGEFCDIKRPSCDPNPCKN-GICQIVGNNRICNCTGTGFTGFDCEISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCPLDFCLNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICPQNYCTKNGNCLVRDDSAVCYCDEGFTGDKCEKPICSKDKCINGGKCVVVDRSPFCVCAKDFQGKSCEKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGXXXXXXXXXXXXYCENGGICSIINNVFICNCSNVSYTGERCTNKVGCPDNYCKNGGACEIHRGKFGCNCSLTGYGGEQCDQKVDGVMCDYKEPGYAITAFKPPMVSSGIVTSMGFQTFVKTGTLFCYETADDKYWLIKLVNGRLVADINGISFNMKTVVSDGRYHFLKVSRDETNFVISLDHFPFENLLIPTAITSILTLPNNIIIYTKLTLCNSCPDTFNRDRFQGAIGSAKSGHVDISKGLKXXXXXXXXXXXXXXXXXLTPVMPLPEIPTIQP--CYAGFCKNSGKCLVKNYGPRCDCGISGFTGNQCDQKIMVIKSVPPNPGYVIITRNPVIATNFDLIRFISESSESSTPLTALITPEGNSIEIKIENQKVFVRINGEAKGPLND-KLIEKNVPNFFKLVNLLGRVTVYVNGTKLGHIVLKEPLIMKNNSIQISKVLVGANRNADETIKGSLGDFRYNELNLISSNGTF--DPNSKQ------IPNI--KLEQWKMIGRKMPDINKVRKGSHGGVVFTSTK-FIIADGFGAGDVVSISNGPIVLGA-QLLGAKTI 4497
            + ++++ P+P +FT  D ++R  PW+F ++ SIE++F T+EPRG+L FVG   A TD + LE ++ N+Y AFG + GKD+R ++NP    V+ G F  + I+    +    KF++VE+     +  + EF SYTYIGG+D  +RLPW  +S+ GF GCINY+R+N ++++D +  + Q   ++ G   G C      C    C  G CH+RSY  L   KNFYCDCS   ++Y     +I R E C  +S+    +  S+ +  F      DK   TH DDI+I F+T      +F      +++   + S +++ G V++   + + +    K +F     NLND +WH + + R A ++  YVD       G++        F N  + I +GS     G +K  G I+NF+WN+ D LG +   G Y   + T KP+LP LPP+PR PP+ CT++P+H YT + +I  T + + ++IEFKT++ GIIWH  ++++S  ++MTL++  N +IL + +   + V+ IE       + DN WHRV+I LNK    + +H+D      + N   +K+      +++ +    GG+ ++  +T  +  LR   P +++  + P+    +GCLG+ L+    +  N +    +N++P  SL C  C+ N  KC   YCQN+G CY +   K+ C+C +  F GE C+    +C  + C+N G C +      C+C+GTGF G +CE S C +  CQNNGIC ++ G+P CDC  T ++G++CE P C   FC N G C ++  N+ P C C +TGF G +C + IC  N+C   G C+ RD    C C   FTG +C +  CS + C N G C + +  P C C K+F+G+ CE  K CP  +C YGG C++ NG P C+C  TNY G +C  PK+CP ++C NGG C + N  + C C    + G RC  +  CP N+CKN G C +    F C+C+ TGY G  C +KV G+  +Y++ GY I    PP+ ++    ++GFQTF+KTGT++ + T D +YW +K+ NG+LV DING  +  ++ V+DG+Y+ + + ++    +  L     E  LI  +   + +   N I Y ++ +  S  +   RD F+GAIG        I + +K       G            ++ +P I    P  C  GFC N+G+C++ +Y P C C  +GF+          +K+V     Y+   +  +  T+ D  +F+ ++  S+ P+      +    EI + + K+    NG+    ++D + ++   P   K +    ++  ++NG +     LK  +I  + S+   K+++GA+++     +G++G F +N   +I  +G      N K       +PN+  K+   K + + +PD+  V  G+HGG++    + ++   G G G +V +  GP++LGA  LLG   I
Sbjct:  461 DYLISATPVPFTFTEFDKLVRFSPWDFEQFESIEIQFRTKEPRGVLLFVGPDNAHTDYVCLEFYDRNLYLAFG-IDGKDYRKQMNPKGTFVTTGNFHTIFIKRDRNHKFTAKFENVEVDIGDQSGHQREFGSYTYIGGIDNPSRLPWYVWSREGFVGCINYMRVNEDKYIDPRGKNNQYSGDIAGVDIGKCLNDVRHCTASHCEGGTCHDRSYPYL-SDKNFYCDCSAISRTYRNPVGNIEREEICARESEEITSDGTSFYVVDFKSEDSRDKMMKTHTDDIAISFKTLQPDATIFQTFRSNSDL---YFSVKLVGGYVVVETNINDKDKFGSKQTFRVPVGNLNDNKWHNIYIKRRAEHILIYVDNVNNQIIGKIPVLKYLRTFDNTFEYIFVGSDNFEAGKEKFVGSIRNFYWNQFDFLGTRRLAGTYKGTIKTPKPSLPPLPPYPRDPPVKCTMRPDHRYTKVTDIAATQDEVGIYIEFKTRYSGIIWHGYDMYNSGRNYMTLMLIDNKLILVHHINEVKSVNIIE-DGSQFQLDDNNWHRVVIMLNKKLRRIIVHVDKGYQPKVINLAVVKS-----IDISKLEFYFGGMPED-LFTNVFTQLRVSLPYLAEKVATPNTWSLVGCLGEFLISEDKFLSNKLSGA-INTYPLNSLDCGGCR-NPLKCEMGYCQNRGLCYQLAIDKLGCNCSEG-FTGEKCEKIEFTCPRDFCRNGGRCYMYDKQPKCDCSGTGFRGNNCEQSFCSDSFCQNNGICSIENGLPVCDCRNTQHKGKVCEKPICSESFCNNRGRCYVH--NEQPICDCTATGFIGQKCEREICTSNFCKNGGLCVPRDSQPTCQCTPEFTGFQCNERKCSSNFCFNDGTCYISNERPQCSCTKNFEGQRCEIEKRCPSDFCYYGGVCQIRNGYPYCDCQNTNYEGTRCNIPKRCPLEFCSNGGNCQVRNGQYYCECQE-GFQGSRCQERKECPPNFCKNDGICSVINNGFICDCTHTGYFGISCSEKVTGLKNEYEKYGYVIYPVSPPVGTTSDQVTVGFQTFMKTGTIYTFRTTDGRYWSLKMDNGKLVIDINGNKYQTQSNVNDGQYYVVSIKKEGERGIFKLLGPQTETFLI--SFDGVTSGVQNEISYKEIIIGASNEE---RDIFKGAIGGFNWNGKYIFEQIKTGQGERKGT---------IEIILVPTIINRPPTSCPKGFCANNGECIIMDYIPYCKCENTGFSDKD-------VKNV-----YMEFFQWRI--THKDETQFLLQAYTSNNPVIRFELNDEQFYEINMIDGKLIFLENGKFPRLISDGQRMDNENPYLVKFIREKEKIKFFINGIQTSSFNLKN-IISNDGSLIHKKIILGADKSYKTYFQGAIGGFEWNGYKMIDDSGNLLNSVNKKGEVIIILMPNLTRKIILPKKV-KPLPDL--VPAGNHGGIIMRPNELYVPGVGSGGGAIVPVGVGPVILGAGSLLGLPVI 1895          

HSP 2 Score: 318.546 bits (815), Expect = 5.043e-87
Identity = 187/487 (38.40%), Postives = 279/487 (57.29%), Query Frame = 1
Query: 4597 VTASGNKLLLIENNDLQISPLLQEKASI-QLISGGFQADTNETMI----HTMRQNRMDMNKT---SDFFTSNGFNKS-TFGTTGSADFEKIQPVKYASIFAQQDTDLQ-QPNVFSEEEMKIDCCVMSNNSRYAITGSVAGPPQVWDLNDGFLTHIMDGANQACTSLHLAMNNSVLIGLV-----TQNQQPFSLKLLMMWKFPDGQIIDSGYEYMCTTCCVSADGECVILADDMKDSSITILNL---TNQQTRKLVYKA-GLVNGDGIQLLKQTKNGQFLIAGFQTFDNSTSYMVFDMTMQSRKNGVF------KINANTNCTDFINNNEAVTGTESGELIIWDLNTVQAVRRILISPNFVDNSESR-NPHKDSLTCVTVSNDGSLLATTGLDATVKVWNMEDEKLLYNLNKHKDEIQSLVWSNDNEMLVSGSLDGSIRIWNVTNGQEMCGFNSNIEITXXXXXXXXXXXXGLGERAGVNKLVMLKIL 5979
            ++A+ N +   ++ D   + + +E+ +I + I G  Q+     ++    H MR  R          ++   N  + S  FGT G     +I            +TD + +PNVF+ EEMK+DCCV+S NSRYA+TGS   PPQ+WD+  G L  +MDG    CT LHLA  + +L+GLV     T+      LK L MW F  G  I    + MC+  C++   + +++  +  D S++I+      NQ  +++ Y+    +N +GI  LK + N + ++AGF   D+   YMVFD+ M S  NG+         NA T  T+ I  +EA+TGT  GELIIW+L T + VR+ILIS     N++++ NPHKD++ C+ VS +G  L T   D TV V+ M DE+L++ L  H D++ S V S DNE++VSGS DGS+R+WN+ +G +MC F SNIEI  V L++DKK +V LGER G+ KL+ML+I+
Sbjct: 2002 LSANANGMAHGDHGDFHSTTIREERGNITRNIGGSMQSLPGGPLLYSGTHNMRSTRSVAGGAPYGHNYGHGNMLDVSDRFGTIGQGSIMRIDT-------THHETDFEGRPNVFAGEEMKVDCCVLSQNSRYAVTGSANSPPQIWDMQTGELFKVMDGMEIGCTDLHLACGDKILVGLVMDEMPTEASDHHRLKRLQMWDFATGSQIAMPLDVMCSASCITHSSDHMVINREYPDGSMSIVCWDLQANQPVQEIHYQTPDFMNHEGITFLKISHNDRMVVAGFTGMDDQAHYMVFDL-MASYPNGIMVQPLISSFNAKTCATEIIGADEAITGTRKGELIIWNLRTAKPVRQILISATLEGNTQTKLNPHKDAINCIAVSKNGEFLVTGSADQTVNVYTMADERLMHTLEGHADDVLSAVISLDNEIIVSGSWDGSMRVWNLESGSQMCWFTSNIEILSVKLTNDKKAIVALGERMGLRKLIMLQII 2480          
The following BLAST results are available for this feature:
BLAST of notch-1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
SNED14.688e-2430.20sushi, nidogen and EGF like domains 1 [Source:HGNC... [more]
SNED16.435e-2430.20sushi, nidogen and EGF like domains 1 [Source:HGNC... [more]
SNED17.239e-2430.20sushi, nidogen and EGF like domains 1 [Source:HGNC... [more]
NOTCH38.559e-2427.36notch receptor 3 [Source:HGNC Symbol;Acc:HGNC:7883... [more]
NOTCH19.479e-2328.73notch receptor 1 [Source:HGNC Symbol;Acc:HGNC:7881... [more]
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BLAST of notch-1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
crb-11.594e-2426.94Drosophila CRumBs homolog [Source:UniProtKB/TrEMB... [more]
clec-783.552e-2131.67C-type LECtin [Source:UniProtKB/TrEMBL;Acc:Q20531... [more]
lin-129.035e-2030.59pep chromosome:WBcel235:III:9060096:9071760:-1 gen... [more]
slt-13.028e-1926.61Slit homolog 1 protein [Source:UniProtKB/Swiss-Pr... [more]
glp-13.582e-1428.40pep chromosome:WBcel235:III:9092241:9099698:1 gene... [more]
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BLAST of notch-1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
N4.865e-2531.20gene:FBgn0004647 transcript:FBtr0304659[more]
N4.865e-2531.20gene:FBgn0004647 transcript:FBtr0070507[more]
Nrx-15.281e-2224.82gene:FBgn0038975 transcript:FBtr0334611[more]
crb9.448e-2227.37gene:FBgn0259685 transcript:FBtr0084603[more]
Nrx-11.038e-2124.68gene:FBgn0038975 transcript:FBtr0334609[more]
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BLAST of notch-1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
notch39.302e-2631.11notch receptor 3 [Source:ZFIN;Acc:ZDB-GENE-000329-... [more]
notch1a1.156e-2429.90notch receptor 1a [Source:NCBI gene;Acc:30718][more]
notch1b1.419e-2330.56notch receptor 1b [Source:ZFIN;Acc:ZDB-GENE-990415... [more]
notch1a4.956e-2329.90notch receptor 1a [Source:NCBI gene;Acc:30718][more]
notch32.244e-2130.00notch receptor 3 [Source:ZFIN;Acc:ZDB-GENE-000329-... [more]
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BLAST of notch-1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
emid11.729e-2627.47EMI domain containing 1 [Source:Xenbase;Acc:XB-GEN... [more]
emid12.157e-2627.47EMI domain containing 1 [Source:Xenbase;Acc:XB-GEN... [more]
emid12.596e-2627.27EMI domain containing 1 [Source:Xenbase;Acc:XB-GEN... [more]
notch12.670e-2429.54notch 1 receptor [Source:NCBI gene;Acc:100037842][more]
notch13.679e-2429.54notch 1 receptor [Source:NCBI gene;Acc:100037842][more]
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BLAST of notch-1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Sned17.681e-2429.70sushi, nidogen and EGF-like domains 1 [Source:MGI ... [more]
Notch14.493e-2228.46notch 1 [Source:MGI Symbol;Acc:MGI:97363][more]
Notch31.676e-2128.49notch 3 [Source:MGI Symbol;Acc:MGI:99460][more]
Notch25.433e-2129.57notch 2 [Source:MGI Symbol;Acc:MGI:97364][more]
Tnxb5.328e-2028.25tenascin XB [Source:MGI Symbol;Acc:MGI:1932137][more]
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BLAST of notch-1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q9R172|NOTC3_RAT2.623e-2430.03Neurogenic locus notch homolog protein 3 OS=Rattus... [more]
sp|P07207|NOTCH_DROME4.876e-2431.20Neurogenic locus Notch protein OS=Drosophila melan... [more]
sp|P21783|NOTC1_XENLA1.140e-2329.81Neurogenic locus notch homolog protein 1 OS=Xenopu... [more]
sp|Q8TER0|SNED1_HUMAN3.476e-2330.20Sushi, nidogen and EGF-like domain-containing prot... [more]
sp|Q9UM47|NOTC3_HUMAN4.110e-2327.36Neurogenic locus notch homolog protein 3 OS=Homo s... [more]
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BLAST of notch-1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0A1CTN91.107e-13100.00Notch-1 (Fragment) OS=Schmidtea mediterranea OX=79... [more]
A0A5K4ELY63.096e-6530.07Cell polarity protein OS=Schistosoma mansoni OX=61... [more]
A0A3Q0KLP92.636e-6530.07Cell polarity protein OS=Schistosoma mansoni OX=61... [more]
A0A068XZS49.213e-14232.94Neurogenic locus notch protein OS=Echinococcus mul... [more]
A0A5K3EZB51.604e-14533.26Uncharacterized protein OS=Mesocestoides corti OX=... [more]
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BLAST of notch-1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
notch1a8.762e-2632.34neurogenic locus notch homolog protein 1 [Source:N... [more]
notch1a1.914e-2532.34neurogenic locus notch homolog protein 1 [Source:N... [more]
ENSAMXT00000055435.11.653e-2124.79protein crumbs homolog 2-like [Source:NCBI gene;Ac... [more]
ENSAMXT00000020429.21.692e-2124.79protein crumbs homolog 2-like [Source:NCBI gene;Ac... [more]
notch32.874e-2130.46neurogenic locus notch homolog protein 2 [Source:N... [more]
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BLAST of notch-1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
JAG11.669e-1729.66jagged canonical Notch ligand 1 [Source:HGNC Symbo... [more]
lrp1ab7.516e-1532.16low density lipoprotein receptor-related protein 1... [more]
ENSPMAT00000002014.11.390e-1433.16pep scaffold:Pmarinus_7.0:GL482490:2146:12219:-1 g... [more]
VWDE2.933e-1330.00von Willebrand factor D and EGF domains [Source:HG... [more]
ENSPMAT00000002643.14.979e-1330.67pep scaffold:Pmarinus_7.0:GL478752:33855:40482:1 g... [more]
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BLAST of notch-1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
TUP13.252e-1127.93General repressor of transcription; forms complex ... [more]
CDC42.382e-825.48F-box protein required for both the G1/S and G2/M ... [more]
RSA49.375e-838.03WD-repeat protein involved in ribosome biogenesis;... [more]
DIP21.123e-725.15Nucleolar protein; specifically associated with th... [more]
TAF56.731e-727.78Subunit (90 kDa) of TFIID and SAGA complexes; invo... [more]
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BLAST of notch-1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO488512.582e-3032.22Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO469693.760e-2435.74Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO337951.432e-2334.08Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO303061.257e-2131.99Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO331991.760e-2131.91Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of notch-1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSORLT00000041634.15.179e-2726.91crumbs cell polarity complex component 2 [Source:N... [more]
ENSORLT00000020612.21.132e-2626.91crumbs cell polarity complex component 2 [Source:N... [more]
notch36.896e-2429.41neurogenic locus notch homolog protein 2 [Source:N... [more]
notch38.904e-2429.41neurogenic locus notch homolog protein 2 [Source:N... [more]
ENSORLT00000015846.21.593e-2027.10protein crumbs homolog 2 [Source:NCBI gene;Acc:101... [more]
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BLAST of notch-1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000056635.10.000e+099.25SMESG000056635.1[more]
SMESG000027800.14.318e-8732.79SMESG000027800.1[more]
SMESG000027800.14.717e-8732.79SMESG000027800.1[more]
SMESG000027800.14.387e-8732.79SMESG000027800.1[more]
SMESG000027800.15.043e-8732.79SMESG000027800.1[more]
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Cross References
External references for this transcript
DatabaseAccession
SmedGD GBrowseSMED30019590
GenBankAIX99542.1
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30019590 ID=SMED30019590|Name=notch-1|organism=Schmidtea mediterranea sexual|type=transcript|length=6155bp
TTTTATCTCAGATTTTATTCAAATTCGGCATTTCAATATAATTGAGCAAA
ATTAATGTGGAAAATTTTAGGTATTTTATTAATATGTCAATCACAGCTGT
CCAAATCACAAATTTCACCGATTGAAGAAGTTATATTGACTTCTCAACCG
ATTCCCGTGTCATTTACAATGCCCGATGCAATGTTACGGTTACATCCATG
GAACTTCGCCAAGTATTCTTCAATTGAACTAGAATTTCATACTCGGGAAC
CAAGAGGGATTTTATTTTTTGTAGGCTCTTCGACTGCTTCGACAGACAGC
ATTGGTTTGGAAATATTCAATTCAAATGTTTATGCATTTGGAAAACTTTT
GGGTAAAGATTTCAGAATTAAGCTCAACCCAGATAACATTAGAGTGTCAA
ATGGGAAGTTCTTTAAAGTTGCTATTCAAATATTGGCCACAAATTACCTA
GTATTAAAATTTGACGATGTGGAAATCAAGGAAAAAATCCCAACTCCTGG
AAAATTGGAATTTAACAGTTACACCTATATTGGAGGAGTAGATACCATTA
CGCGTCTGCCGTGGAAAGCATTTTCCCAAACTGGATTCACAGGATGTATT
AATTACATAAGGATAAATGGAGAAAGGTTTCTCGACACAAAACAACACTC
GAAGCAGACTGAAATGCAAGGAGCTAAAACAGGAGTCTGTCAGACATCAA
CTGCCCGTTGCCTGCCTGGAATATGTGGTCCTGGAAAATGCCACGAAAGA
AGTTACAACATGCTTGATCAATCAAAGAATTTTTACTGTGACTGCTCTGG
AACATTTAAATCCTATGCTTACTCTGCTGTAGACATTCTTAGAGGAGAGC
CTTGTTTAATTGATTCTCAGAGATTCCAGTGCAATACAAAATCCTATTTA
CTTTATACTTTTGACAAAGAGAAAACAACTCATTATGATGATATTTCAAT
AGATTTCCAAACAACAAACACAAAAGAGCCTCTATTTCTCATGAAATCCG
GAACCGCTAATGTGATAAATACATTTTTATCAGCAGAAGTATTAGCTGGT
CAAGTGATAATCATCATTAAGTTATATGAATCCAACAATGAGAATTACAA
ATCTTCTTTTTTCTCAAAGAATTCCAATCTAAATGATGGGCAGTGGCACA
CTTTAAAACTGAGTCGATTCGCTTATAATGTAGAATTTTATGTGGATGAA
CAAGAAACTATATCTAGAGGAGAATTATATCAATCATCACTCGAAGAAAA
GTTTTTCAATAAAGTCAAAGAAATTCTCCTTGGGTCAACTACGAAACCAC
CGGGACCTGATAAATGTACTGGAGAAATAAAGAATTTCTTTTGGAATGAG
GAAGACTTGCTAGGGAGGAAAAACAAATATGGGTATTATTCTAGTCAATT
GGTTACAGAAAAACCTACTTTGCCAATTCTTCCTCCATTCCCTCGCCAGC
CTCCCATGCCTTGCACTCTCAAACCTAATCACATTTATACCGTTTTGAAT
AATATACCATTGACAAATGAAGGCATAATCCTTTTTATAGAATTCAAGAC
GAAATTCGATGGAATAATTTGGCATGCAGTAAATGTCTTTTCCTCAGAAG
ACTGGATGACACTATTAGTGAATTCAAATTCAATTATTCTAGCTTACAGC
TTACCACCGAATGAAGGAGTCCACACAATTGAAATGACTCGAGGTGGAAT
CCTTATCCAAGATAACACATGGCATCGAGTAATAATAAACCTCAATAAAC
CGAAAGAAATTCTGTACATTCACATTGATGATGTTGAATCGCTCACTAAT
GAGATCAAATTGAAAAACTCAAAAAAAGAATTGGCAGAAATGAATTTTAT
TTCTTTAAGTCTTGGTGGGATATCAGATAATAGTCAATATACTCAATTTT
ACAACCTACTTCGGAAAAAAAATCCAGAAGTCAGTAAACTTTTTTCCGGT
CCAGATGAACTTAAATTTATCGGATGCCTTGGAGACATTTTGGTTATAAA
TAGTAGTTATTCTGGTAACCTCATTCAGAAACCCAATGTTAATTCCTTCC
CCAAAGAAAGTCTTTTTTGTCGAGCTTGTCAAGAAAATGTCAAAAAATGT
CCCAAAAACTACTGCCAGAACAAAGGTCGCTGTTACAATATCAATGAAAC
AAAGATTGCATGTGACTGTAAAAAAACTCAATTTTATGGAGAATTTTGTG
ACATTAAACGTCCCAGTTGTGATCCAAATCCGTGTAAAAATGGCATTTGT
CAAATAGTCGGAAATAACCGAATCTGTAATTGTACTGGAACAGGATTCAC
CGGTTTTGATTGTGAAATTAGCAGATGTTTCAATCACAAGTGCCAAAACA
ATGGAATTTGCATTCTTAAACAAGGGATTCCGGAATGTGACTGCACAAAG
ACAGTTTACGAAGGGCAACTTTGTGAAACTCCTAAATGCCCATTGGATTT
CTGTCTAAACAATGGGCATTGTTTATTGAATCAAGTCAATCAACTTCCAT
ACTGTGTTTGCAATAGTACCGGTTTTTACGGCTACCGGTGTAACAAACCT
ATTTGTCCTCAAAACTACTGCACTAAGAATGGAAATTGCCTTGTTAGGGA
CGATTCAGCAGTATGTTACTGTGATGAGGGTTTTACAGGTGACAAGTGCG
AAAAACCGATTTGCTCAAAGGATAAATGCATAAATGGAGGCAAGTGTGTG
GTCGTTGATAGATCTCCGTTTTGTGTTTGCGCTAAAGATTTTCAAGGAAA
AAGTTGTGAGAAACCCAAACCTTGCCCAGTTGGATATTGTTTATATGGAG
GCAAATGTCGAATGGTGAACGGAATGCCTAGATGTAATTGTACACAGACT
AATTACATGGGGAAAAAGTGTGAAAAACCAAAGAAATGTCCTGAAAAATA
TTGTGAAAACGGAGGAATTTGTTCAATAATCAACAATGTTTTTATATGTA
ATTGTTCGAATGTCAGTTACACGGGAGAAAGGTGCACTAATAAAGTTGGC
TGTCCAGACAATTATTGTAAAAATGGTGGAGCATGCGAAATCCATAGGGG
CAAATTTGGTTGTAACTGCTCATTAACCGGATATGGTGGTGAACAATGCG
ATCAAAAAGTAGATGGGGTTATGTGTGATTACAAAGAGCCTGGTTATGCA
ATCACTGCATTTAAGCCACCAATGGTTTCATCTGGAATAGTAACTTCAAT
GGGATTTCAAACGTTTGTTAAAACAGGAACGTTATTTTGTTATGAAACAG
CAGATGATAAATATTGGTTGATTAAATTAGTTAATGGTCGATTGGTCGCA
GATATCAATGGAATTAGCTTCAACATGAAAACTGTAGTCAGTGATGGACG
GTATCATTTTCTCAAAGTCTCTCGAGATGAAACTAATTTTGTTATTTCTC
TTGACCATTTTCCCTTTGAAAATTTATTAATTCCGACTGCCATTACTTCA
ATATTAACATTGCCGAATAATATAATAATTTACACGAAGCTGACGTTATG
TAATTCTTGTCCGGATACATTCAATAGGGATAGATTTCAAGGAGCTATTG
GTAGTGCAAAATCAGGCCATGTCGATATTTCTAAAGGTCTCAAAAATGAT
GGTAATGCTGGTGGTGGTATCATGATTGGTGGCATTACGAATATCTTAAC
GCCTGTCATGCCACTTCCAGAAATACCAACAATTCAACCATGTTATGCAG
GGTTTTGTAAAAATAGTGGGAAATGTTTAGTCAAAAATTATGGTCCGAGA
TGCGATTGTGGAATCAGTGGCTTTACTGGAAATCAATGTGATCAAAAAAT
CATGGTAATTAAATCCGTTCCCCCAAACCCTGGATATGTTATAATCACCC
GCAATCCGGTGATAGCAACTAATTTCGATCTTATTCGCTTTATATCAGAA
TCATCTGAATCTTCAACTCCATTGACAGCACTGATAACGCCAGAAGGAAA
TTCCATAGAGATCAAAATAGAAAATCAGAAAGTATTTGTTCGGATTAATG
GAGAAGCTAAAGGACCATTGAATGACAAACTTATAGAAAAAAATGTTCCA
AACTTCTTTAAATTAGTCAATTTATTGGGTAGAGTAACGGTCTATGTAAA
TGGAACTAAACTAGGTCATATAGTTTTGAAAGAACCTCTAATTATGAAAA
ACAATTCCATTCAAATTTCAAAAGTATTAGTTGGTGCTAATAGGAATGCG
GACGAAACGATTAAAGGATCTCTCGGAGATTTTCGGTACAACGAGTTAAA
TTTGATATCATCAAATGGTACATTTGATCCTAATTCGAAGCAGATACCTA
ACATTAAACTTGAACAGTGGAAAATGATTGGTAGAAAAATGCCAGATATT
AACAAAGTTAGAAAAGGTTCTCATGGTGGTGTTGTTTTTACTTCAACTAA
ATTTATAATTGCTGATGGATTTGGAGCTGGTGATGTTGTATCAATTTCCA
ACGGCCCAATAGTTCTCGGAGCTCAGTTATTGGGTGCTAAAACTATTGGC
GTTGATCCATTCATTTTGGGTATAATTCTAGCGTGCATACTATTGATTAT
AGCTTTAATCTGGGCTTTCATGAATTTGATATTCTCTCGAACTCATGTGA
CAGCTAGTGGAAATAAATTGTTATTAATCGAAAATAATGATTTGCAAATA
AGCCCATTACTACAAGAAAAAGCTTCCATTCAGCTAATCAGTGGAGGTTT
TCAAGCAGATACAAATGAGACAATGATTCACACGATGCGACAAAATAGAA
TGGATATGAATAAAACCAGTGATTTTTTTACAAGCAACGGATTTAACAAA
TCAACATTTGGCACAACTGGCTCAGCAGATTTTGAAAAGATCCAACCTGT
CAAATACGCAAGTATATTTGCGCAACAAGATACTGACCTTCAACAACCCA
ATGTATTTTCCGAAGAGGAAATGAAAATTGACTGTTGCGTAATGAGTAAT
AATAGTAGATATGCCATAACTGGATCAGTGGCGGGTCCTCCTCAAGTATG
GGATTTAAATGATGGGTTTTTAACTCATATAATGGATGGCGCAAATCAAG
CATGCACTTCTCTTCATTTAGCAATGAACAATTCTGTTTTGATTGGATTA
GTTACTCAAAACCAGCAACCTTTCAGTTTGAAATTATTAATGATGTGGAA
GTTTCCAGATGGGCAGATAATTGATTCTGGATACGAGTATATGTGCACAA
CTTGTTGCGTATCAGCCGATGGCGAGTGTGTTATATTAGCGGATGATATG
AAGGATTCTTCCATCACGATTCTTAATCTGACCAATCAGCAAACACGTAA
GCTCGTATATAAAGCGGGATTGGTCAATGGTGACGGAATCCAATTGTTAA
AACAGACGAAAAATGGACAATTTTTAATAGCTGGTTTTCAAACGTTTGAC
AATTCAACTAGTTATATGGTTTTCGATATGACGATGCAATCGAGAAAAAA
TGGTGTATTCAAAATCAACGCAAATACTAATTGCACAGACTTTATCAACA
ATAATGAAGCTGTAACAGGTACTGAAAGTGGAGAATTGATCATTTGGGAT
CTAAATACAGTTCAAGCCGTAAGACGAATTCTTATAAGTCCAAACTTCGT
AGACAATTCAGAGAGCCGAAACCCACACAAAGATTCTTTAACTTGTGTGA
CAGTATCAAACGATGGCTCACTGCTTGCAACTACAGGATTGGACGCAACA
GTTAAAGTATGGAACATGGAGGATGAAAAACTATTATACAATTTGAATAA
ACACAAAGATGAGATCCAAAGCTTGGTTTGGTCCAACGACAACGAAATGC
TTGTTTCTGGTAGCTTAGATGGATCCATACGAATTTGGAATGTCACGAAT
GGGCAAGAGATGTGCGGTTTCAACTCCAACATAGAAATAACCAAGGTATT
GTTGAGCGATGACAAAAAAGTTGTTGTAGGTCTCGGAGAAAGAGCTGGAG
TGAATAAATTAGTTATGCTGAAAATATTAAGAAATATTCATCAAGTTTCG
AGAGACATCAAAGATGAACTCGTGTCTCAACTTCTTTGAAATTTGAGAAA
TATGATTTTTATTGAAATTTGACATAATTTTCACTTAAAGCTATTTTATC
TATTAAGCTGATTTTTCATGTAATTGCCTACATTTAATAAAAGGTTAATT
TTCTT
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protein sequence of SMED30019590-orf-1

>SMED30019590-orf-1 ID=SMED30019590-orf-1|Name=SMED30019590-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1995bp
MWKILGILLICQSQLSKSQISPIEEVILTSQPIPVSFTMPDAMLRLHPWN
FAKYSSIELEFHTREPRGILFFVGSSTASTDSIGLEIFNSNVYAFGKLLG
KDFRIKLNPDNIRVSNGKFFKVAIQILATNYLVLKFDDVEIKEKIPTPGK
LEFNSYTYIGGVDTITRLPWKAFSQTGFTGCINYIRINGERFLDTKQHSK
QTEMQGAKTGVCQTSTARCLPGICGPGKCHERSYNMLDQSKNFYCDCSGT
FKSYAYSAVDILRGEPCLIDSQRFQCNTKSYLLYTFDKEKTTHYDDISID
FQTTNTKEPLFLMKSGTANVINTFLSAEVLAGQVIIIIKLYESNNENYKS
SFFSKNSNLNDGQWHTLKLSRFAYNVEFYVDEQETISRGELYQSSLEEKF
FNKVKEILLGSTTKPPGPDKCTGEIKNFFWNEEDLLGRKNKYGYYSSQLV
TEKPTLPILPPFPRQPPMPCTLKPNHIYTVLNNIPLTNEGIILFIEFKTK
FDGIIWHAVNVFSSEDWMTLLVNSNSIILAYSLPPNEGVHTIEMTRGGIL
IQDNTWHRVIINLNKPKEILYIHIDDVESLTNEIKLKNSKKELAEMNFIS
LSLGGISDNSQYTQFYNLLRKKNPEVSKLFSGPDELKFIGCLGDILVINS
SYSGNLIQKPNVNSFPKESLFCRACQENVKKCPKNYCQNKGRCYNINETK
IACDCKKTQFYGEFCDIKRPSCDPNPCKNGICQIVGNNRICNCTGTGFTG
FDCEISRCFNHKCQNNGICILKQGIPECDCTKTVYEGQLCETPKCPLDFC
LNNGHCLLNQVNQLPYCVCNSTGFYGYRCNKPICPQNYCTKNGNCLVRDD
SAVCYCDEGFTGDKCEKPICSKDKCINGGKCVVVDRSPFCVCAKDFQGKS
CEKPKPCPVGYCLYGGKCRMVNGMPRCNCTQTNYMGKKCEKPKKCPEKYC
ENGGICSIINNVFICNCSNVSYTGERCTNKVGCPDNYCKNGGACEIHRGK
FGCNCSLTGYGGEQCDQKVDGVMCDYKEPGYAITAFKPPMVSSGIVTSMG
FQTFVKTGTLFCYETADDKYWLIKLVNGRLVADINGISFNMKTVVSDGRY
HFLKVSRDETNFVISLDHFPFENLLIPTAITSILTLPNNIIIYTKLTLCN
SCPDTFNRDRFQGAIGSAKSGHVDISKGLKNDGNAGGGIMIGGITNILTP
VMPLPEIPTIQPCYAGFCKNSGKCLVKNYGPRCDCGISGFTGNQCDQKIM
VIKSVPPNPGYVIITRNPVIATNFDLIRFISESSESSTPLTALITPEGNS
IEIKIENQKVFVRINGEAKGPLNDKLIEKNVPNFFKLVNLLGRVTVYVNG
TKLGHIVLKEPLIMKNNSIQISKVLVGANRNADETIKGSLGDFRYNELNL
ISSNGTFDPNSKQIPNIKLEQWKMIGRKMPDINKVRKGSHGGVVFTSTKF
IIADGFGAGDVVSISNGPIVLGAQLLGAKTIGVDPFILGIILACILLIIA
LIWAFMNLIFSRTHVTASGNKLLLIENNDLQISPLLQEKASIQLISGGFQ
ADTNETMIHTMRQNRMDMNKTSDFFTSNGFNKSTFGTTGSADFEKIQPVK
YASIFAQQDTDLQQPNVFSEEEMKIDCCVMSNNSRYAITGSVAGPPQVWD
LNDGFLTHIMDGANQACTSLHLAMNNSVLIGLVTQNQQPFSLKLLMMWKF
PDGQIIDSGYEYMCTTCCVSADGECVILADDMKDSSITILNLTNQQTRKL
VYKAGLVNGDGIQLLKQTKNGQFLIAGFQTFDNSTSYMVFDMTMQSRKNG
VFKINANTNCTDFINNNEAVTGTESGELIIWDLNTVQAVRRILISPNFVD
NSESRNPHKDSLTCVTVSNDGSLLATTGLDATVKVWNMEDEKLLYNLNKH
KDEIQSLVWSNDNEMLVSGSLDGSIRIWNVTNGQEMCGFNSNIEITKVLL
SDDKKVVVGLGERAGVNKLVMLKILRNIHQVSRDIKDELVSQLL*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000018Category 4 cell
PLANA:0000034epidermis
PLANA:0000054dorsal region of the epidermis
PLANA:0000096ventral epidermis
PLANA:0000141dorsal region of the whole animal
PLANA:0002032epidermal cell
Vocabulary: INTERPRO
TermDefinition
IPR011047Quinoprotein_ADH-like_supfam
IPR000742EGF-like_dom
IPR001680WD40_repeat
IPR001791Laminin_G
IPR013320ConA-like_dom_sf
IPR015943WD40/YVTN_repeat-like_dom_sf
IPR019775WD40_repeat_CS
IPR013032EGF-like_CS
IPR017986WD40_repeat_dom
Vocabulary: molecular function
TermDefinition
GO:0005515protein binding
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 577..597
NoneNo IPR availableGENE3DG3DSA:2.60.120.200coord: 32..207
e-value: 4.3E-23
score: 83.9
NoneNo IPR availableGENE3DG3DSA:2.60.120.200coord: 271..445
e-value: 1.5E-19
score: 72.2
coord: 1026..1184
e-value: 3.9E-9
score: 38.2
NoneNo IPR availableGENE3DG3DSA:2.10.25.10coord: 719..755
e-value: 3.1E-5
score: 26.0
NoneNo IPR availableGENE3DG3DSA:2.10.25.10coord: 793..868
e-value: 3.2E-7
score: 32.3
coord: 869..942
e-value: 3.4E-7
score: 32.3
NoneNo IPR availableGENE3DG3DSA:2.60.120.200coord: 476..668
e-value: 1.8E-8
score: 36.2
NoneNo IPR availableGENE3DG3DSA:2.10.25.10coord: 980..1018
e-value: 1.9E-6
score: 29.6
coord: 678..718
e-value: 4.5E-7
score: 31.6
coord: 756..792
e-value: 3.0E-8
score: 35.4
coord: 943..979
e-value: 6.0E-8
score: 34.4
coord: 1209..1248
e-value: 8.8E-6
score: 27.5
NoneNo IPR availablePANTHERPTHR24033FAMILY NOT NAMEDcoord: 200..939
coord: 778..1015
NoneNo IPR availableCDDcd00110LamGcoord: 1029..1121
e-value: 1.49163E-8
score: 53.5761
NoneNo IPR availableCDDcd00110LamGcoord: 34..188
e-value: 1.04785E-16
score: 77.0732
NoneNo IPR availableCDDcd00110LamGcoord: 280..431
e-value: 2.88064E-7
score: 49.7241
NoneNo IPR availableCDDcd00054EGF_CAcoord: 837..866
e-value: 0.00763451
score: 34.1494
NoneNo IPR availableSIGNALP_EUKSignalP-noTMSignalP-noTMcoord: 1..18
score: 0.528
NoneNo IPR availableSUPERFAMILYSSF57196EGF/Laminincoord: 870..903
NoneNo IPR availableSUPERFAMILYSSF57196EGF/Laminincoord: 833..869
NoneNo IPR availableSUPERFAMILYSSF57196EGF/Laminincoord: 679..717
NoneNo IPR availableTMHMMTMhelixcoord: 1485..1507
NoneNo IPR availableTMHMMTMhelixcoord: 1456..1478
IPR000742EGF-like domainSMARTSM00181egf_5coord: 982..1016
e-value: 110.0
score: 3.9
coord: 869..902
e-value: 1.8E-4
score: 30.8
coord: 721..754
e-value: 0.086
score: 22.0
coord: 794..830
e-value: 16.0
score: 13.7
coord: 218..268
e-value: 200.0
score: 1.2
coord: 1212..1246
e-value: 15.0
score: 14.0
coord: 833..866
e-value: 0.047
score: 22.8
coord: 757..791
e-value: 65.0
score: 6.7
coord: 674..716
e-value: 170.0
score: 2.0
coord: 944..978
e-value: 16.0
score: 13.8
coord: 906..940
e-value: 19.0
score: 12.7
IPR000742EGF-like domainPFAMPF00008EGFcoord: 870..899
e-value: 4.3E-5
score: 23.7
IPR000742EGF-like domainPROSITEPS50026EGF_3coord: 1209..1246
score: 12.38
IPR000742EGF-like domainPROSITEPS50026EGF_3coord: 754..791
score: 13.082
IPR000742EGF-like domainPROSITEPS50026EGF_3coord: 941..978
score: 12.769
IPR000742EGF-like domainPROSITEPS50026EGF_3coord: 867..902
score: 12.375
IPR000742EGF-like domainPROSITEPS50026EGF_3coord: 979..1016
score: 14.28
IPR000742EGF-like domainPROSITEPS50026EGF_3coord: 678..716
score: 13.78
IPR000742EGF-like domainPROSITEPS50026EGF_3coord: 903..940
score: 12.97
IPR000742EGF-like domainPROSITEPS50026EGF_3coord: 830..866
score: 15.341
IPR001791Laminin G domainSMARTSM00282LamG_3coord: 293..433
e-value: 1.6E-5
score: 34.4
coord: 53..190
e-value: 5.8E-15
score: 65.7
coord: 489..650
e-value: 0.039
score: 20.6
coord: 1043..1173
e-value: 0.14
score: 13.2
IPR001791Laminin G domainPFAMPF00054Laminin_G_1coord: 1051..1140
e-value: 2.5E-4
score: 21.3
IPR001791Laminin G domainPFAMPF02210Laminin_G_2coord: 61..190
e-value: 9.9E-14
score: 52.0
coord: 312..418
e-value: 1.0E-8
score: 35.8
IPR001791Laminin G domainPROSITEPS50025LAM_G_DOMAINcoord: 468..672
score: 16.856
IPR001791Laminin G domainPROSITEPS50025LAM_G_DOMAINcoord: 33..212
score: 24.524
IPR001791Laminin G domainPROSITEPS50025LAM_G_DOMAINcoord: 271..470
score: 15.405
IPR001680WD40 repeatSMARTSM00320WD40_4coord: 1795..1832
e-value: 15.0
score: 9.5
coord: 1611..1650
e-value: 87.0
score: 4.8
coord: 1845..1887
e-value: 6.2E-5
score: 32.4
coord: 1890..1929
e-value: 2.2E-9
score: 47.1
IPR001680WD40 repeatPFAMPF00400WD40coord: 1858..1887
e-value: 0.0025
score: 18.6
coord: 1892..1929
e-value: 7.9E-6
score: 26.5
IPR001680WD40 repeatPROSITEPS50082WD_REPEATS_2coord: 1855..1896
score: 13.75
IPR001680WD40 repeatPROSITEPS50082WD_REPEATS_2coord: 1897..1938
score: 16.423
IPR015943WD40/YVTN repeat-like-containing domain superfamilyGENE3DG3DSA:2.130.10.10coord: 1856..1992
e-value: 2.1E-28
score: 101.5
IPR015943WD40/YVTN repeat-like-containing domain superfamilyGENE3DG3DSA:2.130.10.10coord: 1588..1853
e-value: 6.2E-14
score: 53.7
IPR013032EGF-like, conserved sitePROSITEPS00022EGF_1coord: 854..865
IPR013032EGF-like, conserved sitePROSITEPS01186EGF_2coord: 854..865
IPR013032EGF-like, conserved sitePROSITEPS00022EGF_1coord: 890..901
IPR019775WD40 repeat, conserved sitePROSITEPS00678WD_REPEATS_1coord: 1874..1888
IPR019775WD40 repeat, conserved sitePROSITEPS00678WD_REPEATS_1coord: 1916..1930
IPR017986WD40-repeat-containing domainPROSITEPS50294WD_REPEATS_REGIONcoord: 1794..1938
score: 25.918
IPR013320Concanavalin A-like lectin/glucanase domain superfamilySUPERFAMILYSSF49899Concanavalin A-like lectins/glucanasescoord: 34..195
IPR013320Concanavalin A-like lectin/glucanase domain superfamilySUPERFAMILYSSF49899Concanavalin A-like lectins/glucanasescoord: 1003..1167
IPR013320Concanavalin A-like lectin/glucanase domain superfamilySUPERFAMILYSSF49899Concanavalin A-like lectins/glucanasescoord: 496..652
IPR013320Concanavalin A-like lectin/glucanase domain superfamilySUPERFAMILYSSF49899Concanavalin A-like lectins/glucanasescoord: 263..388
IPR011047Quinoprotein alcohol dehydrogenase-like superfamilySUPERFAMILYSSF50998Quinoprotein alcohol dehydrogenase-likecoord: 1620..1959