Acetylcholine receptor subunit alpha-like protein

Query:  475 ILFFTTHGKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHAVDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKYXXXXXXXXXXXXXXXXXXXXXXXRSTMT-HSMSPWIRYXXXXXXXXXXXXHSPISKEKEMSERCFMYCNKTMFKEASASKLIYETFMRRSKRSYSLKDASIEEKINRTIADLKYVVDNLKDDDYKNKVQEEWRFVAVVMDRVFLLLFLSACVISTGSIILRSPAL 1575
            +LF    G++E  LMTK  V  +GTV WTPPA Y+SSC ++V FFP+D QNC M F SWTY D  MV                  ++IN  VD ++F+ + E++IL     +  R+    S  +P +T++ ++RR  LFYT+ LI+PCL +SFL+VLVFYLP+  GEK+SLS ++L+SLT+F L++ E IPS+S VIPLIG+YLLF +I ++LSII+TV V+NV+ RS+ T H M+PW++ +FL            + K   M +    Y +    KE S   +  +   ++ ++  S  +  +   + +    ++Y+  ++K + + ++V ++W+FVA V+DR+FL LFL   V  TGS+++ +PAL
Sbjct:  116 VLFENADGRFEGSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTY-DGTMV----------------DLILINENVDRKDFFDNGEWEILNAKGMKGNRRDGVYS--YPFITYSFVLRRLPLFYTLFLIIPCLGLSFLTVLVFYLPSDEGEKLSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLLFIMIFVTLSIIVTVFVINVHHRSSSTYHPMAPWVKRLFL----------QKLPKLLCMKDHVDRYSSPE--KEESQPVVKGKVLEKKKQKQLSDGEKVLVAFLEKAADSIRYISRHVKKEHFISQVVQDWKFVAQVLDRIFLWLFLIVSV--TGSVLIFTPAL 450          

Query:  189 QTSTGFKSAVQLYQKLLDE--NNYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLY 488
              +TGF S  +    LL      Y K +RPV  + D +  YFGLK++QL+D++ ++Q +TTNVW++QEW D  LRWNP+DY G+  + +PS  +WLPDIVL+
Sbjct:   17 SATTGFNSIAENEDALLRHLFQGYQKWVRPVLHSNDTIKVYFGLKISQLVDVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLF 118          

Query:  475 ILFFTTHGKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHAVDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKYXXXXXXXXXXXXXXXXXXXXXXXRSTMTHSMSPWIRYXXXXXXXXXXXXHSPISK--------------------------EKEMSERCFMYCNKTMFKEASASKLIYETFMRRSKRSYSLKDASIEEKINRTIADLKYVVDNLKDDDYKNKVQEEWRFVAVVMDRVFLLLFLSACVISTGSIILRSPALYDRRTPLDGN 1605
            +L+    G ++V+  TKA + ++G + WTPPA+++SSC +++ FFP+D QNC + F SWTY+  ++ L                 ++I   VD+ +F+ + E++I++ S  +H  ++    E + ++T++  +RR  +FYT+NLI+PCL +SFL+VLVFYLP+  GEK++L I++LLSLT+F L++ ETIPSTSLV+PL+G+YLLFT+I ++LSI++TV VLN+++R+  TH+M  W++ +FLK LP +L +  P+ K                          E    + CF +C+K+     S  +L ++         + ++++    ++   I  ++++ +N+K  +   +V+++W++VA+V+DRVFL +F+  CV  T  + L+         PL GN
Sbjct:  121 VLYNNAVGDFQVEGKTKALLKYNGMITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDL-----------------LIIGSKVDMNDFWENSEWEIIDASGYKHDIKYNCCEEIYTDITYSFYIRRLPMFYTINLIIPCLFISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVVPLVGEYLLFTMIFVTLSIVVTVFVLNIHYRTPTTHTMPRWVKTVFLKLLPQVLLMRWPLDKTRGTGSDAVPRGLARRPAKGKLASHGEPRHLKECF-HCHKSNELATSKRRLSHQPL------QWVVENSEHSPEVEDVINSVQFIAENMKSHNETKEVEDDWKYVAMVVDRVFLWVFIIVCVFGTAGLFLQ---------PLLGN 490          

Query:  189 QTSTGFKSAVQLYQKLLDENNYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLYN 491
            +   G  +  +L+ KL   ++YN+ IRPVE   D VT +F + +TQL +++  +Q + TN+W++  W D  LRW+P +Y+G++ L +P++KIW PDIVLYN
Sbjct:   26 KGCVGCATEERLFHKLF--SHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLRHIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYN 124          

Query:  475 ILFFTTHGKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHAVDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKYXXXXXXXXXXXXXXXXXXXXXXXRSTMTHSMSPWIRYXXXXXXXXXXXXHSP-----ISKEKEMSERCF--------------MYCNKTMF--KEASASKLIYETFMRRSKRSYSLKDAS-IEEKINRTIADLKYVVDNLKDDDYKNKVQEEWRFVAVVMDRVFLLLFLSACVISTGSIILRSPALYDRRTPLDGNH 1608
            +L+    G YEV + T   V  +G+V W PPA+Y+S+C I V++FP+D QNC + F SWTY DH  +                  V++     + +F  S E+DI+ L  RR +     +   + +VT++ I++RK LFYT+NLI+PC+  + L++LVFYLP+  GEK++L I++LL+LT F LL+ + +P TSL +PLIGKYL+FT++L++ SI+ +V VLNV+ RS  TH+M+PW++  FL  LP  LF+  P      ++    S+ C                Y N   F    ++ASK    +      R + L+ +    + +   +  + ++  ++K+DD    V E+W++VA+V+DR+FL +F+  CV+ T  + L  P L+      +G +
Sbjct:  116 VLYNNADGTYEVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTY-DHTEI----------------DMVLMTPTASMDDFTPSGEWDIVALPGRRTVNP---QDPSYVDVTYDFIIKRKPLFYTINLIIPCVLTTLLAILVFYLPSDCGEKMTLCISVLLALTFFLLLISKIVPPTSLDVPLIGKYLMFTMVLVTFSIVTSVCVLNVHHRSPSTHTMAPWVKRCFLHKLPTFLFMKRPGPDSSPARAFPPSKSCVTKPEATATSTSPSNFYGNSMYFVNPASAASKSPAGSTPVAIPRDFWLRSSGRFRQDVQEALEGVSFIAQHMKNDDEDQSVVEDWKYVAMVVDRLFLWVFMFVCVLGTVGLFL--PPLFQTHAASEGPY 493          

Query:  219 QLYQKLLDENNYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLYN 491
            +L   LL++  YN LIRP   +   ++    L L QLI +N R+Q +TTNVW++QEW D  L WN   YEGV +L IP+ +IWLPDIVLYN
Sbjct:   29 KLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYN 119          

Query:  475 ILFFTTHGKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHAVDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKYXXXXXXXXXXXXXXXXXXXXXXXRSTMTHSMSPWIRYXXXXXXXXXXXXHSP------------------------ISKEKEMSERCFMYCNKTMFKEASASKLIYETFMRRSKRSYSLKDASIEEKINRTIADLKYVVDNLKDDDYKNKVQEEWRFVAVVMDRVFLLLFLSACVISTGSIILR 1563
            +L+    G YEV   + A V +DG++ W PPA+Y+S+C I V+ FP+D QNC M F SWTY+  ++ L                 V+ +    L +F  S E+DI+ L  RR+      +   + ++T++ I+RRK LFYT+NLI+PC+ ++ L++LVFYLP+  GEK++L I++LL+LT+F LL+ + +P TSL +PL+GKYL+FT++L++ SI+ +V VLNV+ RS  TH+M+PW++ +FL+ LP +LF+  P                          +E   ++ C  + N+   +  + +       +    RS       + E ++     ++++ D+++ +D    V E+W++VA+V+DR+FL +F+  CV  T  + L+
Sbjct:  118 VLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRSWTYDRTEIDL-----------------VLKSEVASLDDFTPSGEWDIVALPGRRNENP---DDSTYVDITYDFIIRRKPLFYTINLIIPCVLITSLAILVFYLPSDCGEKMTLCISVLLALTVFLLLISKIVPPTSLDVPLVGKYLMFTMVLVTFSIVTSVCVLNVHHRSPTTHTMAPWVKVVFLEKLPALLFMQQPRHHCARQRLRLRRRQREREGAGALFFREAPGADSCTCFVNRASVQGLAGAFGAEPAPVAGPGRSGEPCGCGLREAVD----GVRFIADHMRSEDDDQSVSEDWKYVAMVIDRLFLWIFVFVCVFGTIGMFLQ 480          

Query:  219 QLYQKLLDENNYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLYN 491
            +L + LLD + YNKLIRP     + VT    + L QLI ++ R+Q +TTNVW+ QEW+D  L W PE+++ ++ + +PS  IWLPD+VLYN
Sbjct:   31 RLVEHLLDPSRYNKLIRPATNGSELVTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLPDVVLYN 121          

Query:  475 ILFFTTHGKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHAVDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKYXXXXXXXXXXXXXXXXXXXXXXXRSTMTHSMSPWIRYXXXXXXXXXXXXHSP------------------------ISKEKEMSERCFMYCNKTMFKEASASKLIYETFMRRSKRSYSLKDASIEEKINRTIADLKYVVDNLKDDDYKNKVQEEWRFVAVVMDRVFLLLFLSACVISTGSIILR 1563
            +L+    G YEV   + A V +DG++ W PPA+Y+S+C I V+ FP+D QNC M F SWTY+  ++ L                 V+ +    L +F  S E+DI+ L  RR+      +   + ++T++ I+RRK LFYT+NLI+PC+ ++ L++LVFYLP+  GEK++L I++LL+LT+F LL+ + +P TSL +PL+GKYL+FT++L++ SI+ +V VLNV+ RS  TH+M+PW++ +FL+ LP +LF+  P                          +E   ++ C  + N+   +  + +       +    RS       + E ++     ++++ D+++ +D    V E+W++VA+V+DR+FL +F+  CV  T  + L+
Sbjct:  118 VLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRSWTYDRTEIDL-----------------VLKSEVASLDDFTPSGEWDIVALPGRRNENP---DDSTYVDITYDFIIRRKPLFYTINLIIPCVLITSLAILVFYLPSDCGEKMTLCISVLLALTVFLLLISKIVPPTSLDVPLVGKYLMFTMVLVTFSIVTSVCVLNVHHRSPTTHTMAPWVKVVFLEKLPALLFMQQPRHHCARQRLRLRRRQREREGAGALFFREAPGADSCTCFVNRASVQGLAGAFGAEPAPVAGPGRSGEPCGCGLREAVD----GVRFIADHMRSEDDDQSVSEDWKYVAMVIDRLFLWIFVFVCVFGTIGMFLQ 480          

Query:  219 QLYQKLLDENNYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLYN 491
            +L + LLD + YNKLIRP     + VT    + L QLI ++ R+Q +TTNVW+ QEW+D  L W PE+++ ++ + +PS  IWLPD+VLYN
Sbjct:   31 RLVEHLLDPSRYNKLIRPATNGSELVTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLPDVVLYN 121          

Query:  475 ILFFTTHGKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKH---YTQKGI-PDSSNTSGTV-----VINHAVDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKYXXXXXXXXXXXXXXXXXXXXXXXRSTMTHSMSPWIRYXXXXXXXXXXXXHSP------ISKEKEMSERCFMYCNKTMFKEASASKLIYETF-MRRSKRSYSL-KDASIEEKINRTIADLKYVVDNLKDDDYKNKVQEEWRFVAVVMDRVFLLLFLSACVISTGSIILRSPALYDRRTPL 1596
            +L+    G Y+V +MTKAK+ ++GTV+W PPA+Y+S C I+VEFFP+D Q C+M F SWTY   ++ L+H   + +K I  D     G       V++  +DL ++Y SVE+DIL +  +RH +++      F ++T+ I +RRKTLFYTVNLI P + +SFL+ LVFYLP+  GEKISL I+IL+SLT+FFLLLVE IPSTSLVIPLIGKYLLFT++L++LS+++TV+ LNV++RS  TH+M  W++ +F+ FLP  L +  P          ++   R   +           S+L+       R + S++L +D S    +   +  + Y+ D+LK+++   +V E+W++++VVMDR+FL+ F  AC   T  II R+P++YD    L
Sbjct:  114 VLYNNADGNYQVTIMTKAKLTYNGTVEWAPPAIYKSMCQIDVEFFPFDRQQCEMKFGSWTYGGLEVDLQHRDKHLEKEIEEDVEGVDGPTKEIVWVVDRGIDLSDYYPSVEWDILNVPGKRHSKRYPCCESPFIDITYEIHLRRKTLFYTVNLIFPSVGISFLTALVFYLPSDGGEKISLCISILISLTVFFLLLVEIIPSTSLVIPLIGKYLLFTMVLVTLSVVVTVVTLNVHYRSPTTHTMPKWMKRLFVDFLPKYLLMTRPQPPGHHSKPNRKFDSRASTFSIGVNHVLGQNSELLSPGLNSNREESSFTLPRDNS---PVRSAVESVAYIADHLKNEEDDKQVIEDWKYISVVMDRIFLITFTFACAFGTVVIIARAPSIYDNTPAL 501          

Query:  207 KSAVQLYQKLLDENNYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLYN 491
            + A +L++ L+   +YNKL+RPV  N + +   F LKL+QL+D++ ++Q +TTNVW+Q  W D  LRW+P +Y GV++L++PS+ IWLPD+VLYN
Sbjct:   25 RDANRLFEDLI--ADYNKLVRPVSENGETLVVTFKLKLSQLLDVHEKNQIMTTNVWLQHSWMDYKLRWDPVEYGGVEVLYVPSDTIWLPDVVLYN 117          

Query:  475 ILFFTTHGKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLK----------HYTQKGIPDSSNTSGTVVINHAVDLRNFYTSVEFDILELSARRHIRQFQG--ESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKYXXXXXXXXXXXXXXXXXXXXXXXRSTMTHSMSPWIRYXXXXXXXXXXXXHSPISKEKEMSERCFMYCNKTMFKEASASKLIYETFMRRSKRSYSLKDASIEEKINR---------TIADLKYVVDNLKDDDYKNKVQEEWRFVAVVMDRVFLLLFLSACVISTGSIILRSPALYDRRTPLDGNHLP 1614
            +L+      Y + + TKA + + G V W PPA+++S C I+V +FP+D Q C + F SWT++++ + ++             +KGI D+       V    +DL ++Y SVE+DI+   A+R  + +        + +VT+ + +RRK LFYTVNL+ PC+ +SFL++LVFYLP+ SGEK++L I+IL++LT+FFLLL E IP+TS+ +PLIGKYLLFT+++++LS+++TVI LN++FR+  TH M  W++ +FLK+LP +LF+  PI   +E  +      +  +     A         R S    ++++A+I++ I +            ++ ++ + LK  D  +K+ E+W++VA+V+DR+FLL+F  AC + T  I+LR+P LYD R P+D  + P
Sbjct:  114 VLYNNADSNYNITISTKATLHYTGEVTWEPPAIFKSMCQIDVRWFPFDEQQCHLKFGSWTFSENLLSVELNEPSLRYEEEIDEKGIIDN-----VTVAEDGIDLSDYYPSVEWDIMSRVAKRRAKNYPSCCPQSAYIDVTYYLQLRRKPLFYTVNLVFPCVGISFLTILVFYLPSDSGEKVTLCISILVALTIFFLLLTEIIPATSITLPLIGKYLLFTMVMVTLSVVVTVISLNLHFRTPTTHLMPNWVKKVFLKWLPKLLFMRRPIDDYEEKFDDKKKPKDGKIALSVHAH--------RVSNVGNNIRNATIDDTIQKMYYSPPVVKAFENICFIAELLKKKDRDDKIDEDWKYVAMVLDRLFLLIFSIACFVGTVIILLRAPTLYDTRQPIDLQYRP 501          

Query:  201 GFKSAVQLYQKLLDENNYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLYN 491
            G + A +LY  L+   NYN+  RP       +T    L+L+Q+ID++  DQ +T +VW++Q W D  L W+P +Y GV +L++P   IW+PDIVLYN
Sbjct:   23 GNEDAKRLYDDLM--VNYNRHRRPSTSPNKPLTIKLKLRLSQIIDVHEIDQIMTCSVWLKQTWIDRKLSWDPVNYGGVNVLYVPYEMIWVPDIVLYN 117          

Query:  475 ILFFTTHGKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTV-VINHAVDLRNFYTSVEFDILELSARRHIRQFQG--ESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKYXXXXXXXXXXXXXXXXXXXXXXXRSTMTHSMSPWIRYXXXXXXXXXXXXHSP----ISKEKEMSERCFM--------------YCNKTMFK---------EASASKLIYETFMRRSKRSYSLKDASIEEKI-----------------------NRTIADLKYV---------VDNLKDDDYKNKVQEEWRFVAVVMDRVFLLLFLSACVISTGSIILRSPALYDRRTPLDGNHLPNQTL 1626
            +L+    G  ++ ++T A V  +G V W PPA+Y+S C I+V +FPYD Q C+M F +WTY    + LK   Q+ +   +     V  +   +DL  FY S E+D+L L++ RH   +      EK+ ++T+   +RRKTLF+T NLI+PC  +S L+  VFYL   S  KI+ SI+IL++LT+FFL+L++ +P TSLVIP+ G+YL+ T+IL++LS +++VI +N  FRS   H MSPWIR +FLKFLP IL +  P    ++K+  +     +              Y NK   K         + S+  ++  TF  R + +    D+++E ++                       ++++ D+ ++          ++ + ++ + ++ ++W FVA+V+DR+FL++F S   + T  IIL SP+LYD   P++   +PN+ L
Sbjct:  125 VLYNNAAGDPDITILTDALVTFEGNVYWQPPAIYKSFCPIDVTWFPYDSQKCEMKFGTWTYTGRYVDLKQLPQEEVVTITKDDNDVEFMQQGMDLSFFYRSAEWDLLSLTSERHSVLYASCCGPEKYVDITYYFGLRRKTLFFTCNLILPCFLISILTTFVFYL---SDHKITFSISILVTLTVFFLVLIDLMPPTSLVIPMFGRYLITTMILVALSTVVSVITVNFRFRSGSAHKMSPWIRAVFLKFLPKILLMSRPEKGEVTKQPPLVNAASLVGSNYATAAKAANEYRNKAKGKNNDLMSLRGKPSSQAVLNNTFDMRMRNN----DSTVENRLKPYLCAQNNNAPTVAFRKTKRQKSKSVDDVVFMNLLNQVRFIAEHFRHNELEGEISDDWTFVAMVLDRLFLIIF-SVLNVGTVFIILESPSLYDYSKPMNIT-VPNKPL 561          

Query:  219 QLYQKLLDENNYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLYN 491
            QLY+ LL +  YNK+ RPV+ + D +T   G  L ++ID++ ++Q LTTN+W++ +W D  L W PE Y G++ LHIPS+ IW PD+VLYN
Sbjct:   40 QLYEDLLFD--YNKVPRPVKNSSDILTVDVGASLIRIIDVDEKNQVLTTNLWLEMKWNDAKLTWTPEKYGGLKTLHIPSDFIWTPDLVLYN 128          

Query:  475 ILFFTTHGKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHAVDLRNFYTSVEFDILELSARRHIRQFQG--ESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKYXXXXXXXXXXXXXXXXXXXXXXXRSTMTHSMSPWIRYXXXXXXXXXXXXHSPISKEKEMSERCFMYCNKTMFKEASASKLIYETFMRR--SKRSYSLKDASIEEKINRT-IADLKYVVDNLKDDDYKNKVQEEWRFVAVVMDRVFLLLFLSACVISTGSIILRSPALYDRRTPL 1596
            +L+    G+  + +M+ A V+++G V W PP++Y+S C I++E+FPYD Q C M F  WTYN   + ++    +       T    V  HA  +  F+ S+E+D++EL++ RH + + G    + + ++TF I +RRKTLFYT+NL++PC   + L+ +VFY+P     K++ SI+IL++LT+F+L+L++ +P TSLVIPLIGKYLLFT+ L+S+SI+++VI LN   R   +  M  W++ +F+  LP  + + +  ++E + S+R     +   F ++      + T   R  + R   LK   +   + R  I +++++ +       ++KV E+W +VA V+DR+FL++F    V+ T  I+L SPAL+D RTPL
Sbjct:  112 LLYNNADGEPHITIMSDAIVYYNGLVVWKPPSIYKSFCSIDIEYFPYDTQTCWMKFGGWTYNGFLLDVRQLPVEEWTLVVTTRKLQVCAHASSISFFFRSLEWDLMELNSARHEKIYAGCCGQDFYIDITFKIEIRRKTLFYTINLMIPCTMFAILTSIVFYVPPIE-HKMTFSISILVTLTVFYLILIDLVPPTSLVIPLIGKYLLFTMFLVSISIMLSVISLNFYRRDGSSFPMPHWMKVVFIHTLPRYICIKT--AEEDDGSDRGSSISDIGPFMDSRRPSPFFITVNERQLNGRLSELKKKGMHPDLIRNMIQNVEFIAEYFNSLKKEDKVSEDWSYVANVIDRIFLIIFSIMNVVGTWVILLNSPALFDNRTPL 487          

Query:  207 KSAVQLYQKLLDENNYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLYN 491
            + A Q+Y+ LL    YNK +RP++   ++V   FG  L ++ID++  +Q LTTN+W++ +W D  L W+P  +  ++ LH+P ++IW+PDI+LYN
Sbjct:   23 RYADQMYEDLL--YYYNKNVRPIKNASESVKVKFGSSLIRIIDVDEVNQVLTTNLWLEMQWFDYRLMWDPGRWGKIRKLHVPVDQIWIPDILLYN 115          

Query:  475 ILFFTTHGKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHAVDLRNFYTSVEFDILELSARRHIRQFQG--ESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKYXXXXXXXXXXXXXXXXXXXXXXXRSTMTHSMSPWIRYXXXXXXXXXXXXHSPISKEKEMSERCFMYCNKTMFKEASASKLIYETFMRR--SKRSYSLKDASIEEKINRT-IADLKYVVDNLKDDDYKNKVQEEWRFVAVVMDRVFLLLFLSACVISTGSIILRSPALYDRRTPL 1596
            +L+    G+  + +M+ A V+++G V W PP++Y+S C I++E+FPYD Q C M F  WTYN   + ++    +       T    V  HA  +  F+ S+E+D++EL++ RH + + G    + + ++TF I +RRKTLFYT+NL++PC   + L+ +VFY+P     K++ SI+IL++LT+F+L+L++ +P TSLVIPLIGKYLLFT+ L+S+SI+++VI LN   R   +  M  W++ +F+  LP  + + +  ++E + S+R     +   F ++      + T   R  + R   LK   +   + R  I +++++ +       ++KV E+W +VA V+DR+FL++F    V+ T  I+L SPAL+D RTPL
Sbjct:  112 LLYNNADGEPHITIMSDAIVYYNGLVVWKPPSIYKSFCSIDIEYFPYDTQTCWMKFGGWTYNGFLLDVRQLPVEEWTLVVTTRKLQVCAHASSISFFFRSLEWDLMELNSARHEKIYAGCCGQDFYIDITFKIEIRRKTLFYTINLMIPCTMFAILTSIVFYVPPIE-HKMTFSISILVTLTVFYLILIDLVPPTSLVIPLIGKYLLFTMFLVSISIMLSVISLNFYRRDGSSFPMPHWMKVVFIHTLPRYICIKT--AEEDDGSDRGSSISDIGPFMDSRRPSPFFITVNERQLNGRLSELKKKGMHPDLIRNMIQNVEFIAEYFNSLKKEDKVSEDWSYVANVIDRIFLIIFSIMNVVGTWVILLNSPALFDNRTPL 487          

Query:  207 KSAVQLYQKLLDENNYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLYN 491
            + A Q+Y+ LL    YNK +RP++   ++V   FG  L ++ID++  +Q LTTN+W++ +W D  L W+P  +  ++ LH+P ++IW+PDI+LYN
Sbjct:   23 RYADQMYEDLL--YYYNKNVRPIKNASESVKVKFGSSLIRIIDVDEVNQVLTTNLWLEMQWFDYRLMWDPGRWGKIRKLHVPVDQIWIPDILLYN 115          

Query:  475 ILFFTTHGKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHAVDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKYXXXXXXXXXXXXXXXXXXXXXXXRSTMTHSMSPWIR-----YXXXXXXXXXXXXHSPISKE--------KEMSERCFMYCNKTMFKEASASKLIYETFMRRSKRSYSLKDASIEEKINRTIADLKYVVDNLKDDDYKNKVQEEWRFVAVVMDRVFLLLFLSACVISTGSIILRSPALYDRRTPLD 1599
            +L+    G YEV LMTKA + + G V W PPA+Y+SSC +NVE+FPYD Q C M F SWTYN  ++ LKH  Q  IP      G+ ++   +DL  FY SVE+DILE+ A ++   +    E F ++TF + MRRKTLFYTVNLI+PC+A++FL+VLVFYLP+ SGEK++L I+IL+SLT+FFLLL E IP TSL +PL+GKYLLFT+IL+SLS+  TV VLN++FRS  TH+MSP +R     ++    +        P   +         E+  R  +    + FK++      Y+  M+ S  S ++   ++  ++ + +  ++++  ++KD D  N++ E+W+FV++V+DR FL LF  +CV  T +II +SP+LYD R+P+D
Sbjct:  117 VLYNNWDGNYEVTLMTKATLKYTGEVFWEPPAIYKSSCEMNVEYFPYDEQICFMKFGSWTYNGAQVDLKHLDQ--IP------GSNLVQVGIDLTEFYLSVEWDILEVPATKNEEYYPDTLEPFSDITFKLTMRRKTLFYTVNLIVPCVALTFLTVLVFYLPSDSGEKVTLCISILVSLTVFFLLLAEIIPPTSLAVPLLGKYLLFTMILVSLSVWTTVCVLNIHFRSPSTHNMSPLVRKLFLHFMPKLMMMRRTQYTLPDYDDSTPSNGYTNEIDVRDSISDFPSEFKDSQDGA--YDNGMQNSVDSDNVIPRNLTPEVLQALRAVRFIAQHIKDADKDNEIVEDWKFVSMVLDRFFLWLFTLSCVFGTLAIICQSPSLYDTRSPID 494          

Query:  219 QLYQKLLDENNYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLYNTW 497
            +LY  LL  +NYN+LIRPV  N + +T + GLKL+QLI++N+++Q +TTN+WV+Q W D  LRW+PE+Y GV+ L++PS  IW+PDIVLYN W
Sbjct:   32 RLYDDLL--SNYNRLIRPVVNNTETLTVWLGLKLSQLIEVNLKNQVMTTNLWVKQRWFDYKLRWDPEEYGGVEQLYVPSEHIWVPDIVLYNNW 122          

Query:  475 ILFFTTHGKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHAVDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKYXXXXXXXXXXXXXXXXXXXXXXXRSTMTHSMSPWIRYXXXXXXXXXXXXHSP-------ISKEKEMSERCFMYCNKTMFKEASASKLIYETFMR---RSKRSYSLKDASIEE-----KINRTIADLKYVVDNLKDDDYKNKVQEEWRFVAVVMDRVFLLLFLSACVISTGSIILRSPALYDRRTPL 1596
            +L+    G +EV L TKA ++ +G V+W PPA+Y+SSC I+VE+FP+D Q C + F SWTY+  K+ L+H  ++         G+ V+   VDL  FY SVE+DILE+ A R+ + +    E + ++TFNI MRRKTLFYTVN+I+PC+ +SFL+VL FYLP+ SGEK++LSI+IL+SL +FFLL+VE IP TSLV+PL+GKYL+F +IL+S+SI +TV+VLNV+FRS  TH M+PW++ +F+ FLP  LF+  P       I+        C ++         S+ ++     M       +S  L + +        KI+++   ++++ ++ K  +   KV+E+W++VA+V+DR+FL +F  A V+ T  IIL++P LYD R P+
Sbjct:   99 VLYNNADGNFEVTLATKATIYSEGLVEWKPPAIYKSSCEIDVEYFPFDEQTCVLKFGSWTYDGFKVDLRHMDEQ--------QGSNVVAVGVDLSEFYMSVEWDILEVPAVRNEKFYTCCDEPYLDITFNITMRRKTLFYTVNIIIPCMGISFLTVLTFYLPSDSGEKVTLSISILISLHVFFLLVVEIIPPTSLVVPLLGKYLIFAMILVSISICVTVVVLNVHFRSPQTHKMAPWVKRVFIDFLPAFLFIKRPTYNFETSITANGPFGGSCQVHGPVPPLTHCSSDEIAAVPDMDIGPLGMKSPILNNPAFSHSKCLPKIHKSCFCVRFIAEHTKMQEDSTKVKEDWKYVAMVLDRLFLWIFTLAVVVGTAGIILQAPTLYDDRIPI 479          

Query:  198 TGFKSAVQLYQKLLDENNYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLYN 491
             G   A +LY  LL  +NYNKL+RPV    D +     LKL+QLID+N+++Q +TTN+WV+Q W D  LRW P++Y GV +LH+PS+ IW PDIVLYN
Sbjct:    7 AGNPDAKRLYDDLL--SNYNKLVRPVVNTTDVLKVCIKLKLSQLIDVNLKNQIMTTNLWVEQSWYDYKLRWEPKEYGGVHMLHVPSDHIWRPDIVLYN 102          

Query:  475 ILFFTTHGKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHAVDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKYXXXXXXXXXXXXXXXXXXXXXXXRSTMTHSMSPWIR 1191
            +L+    G YEV LMTKA V+++G V W PPAVY+SSC I+VE+FPYD+Q C +   SWTY+  K+ L+H  ++         G+ V+   VDL  FY SVE+DILE+ A R+ + +    E + ++TFNI MRRKTLFYTVN+I+PC+ +SFL+VL FYLP+ SGEK++LSI+IL+SL +FFLL+VE IP TSLV+PL+GKYL+F +IL+S+SI +TV+VLNV+FRS  TH M+PW++
Sbjct:   99 VLYNNADGHYEVTLMTKAIVYNNGLVIWQPPAVYKSSCSIDVEYFPYDVQTCILKLGSWTYDGFKVDLRHMDEQ--------QGSNVVAVGVDLSEFYMSVEWDILEVPAVRNEKFYTCCDEPYLDITFNITMRRKTLFYTVNIIIPCMGISFLTVLTFYLPSDSGEKVTLSISILISLHVFFLLVVEIIPPTSLVVPLLGKYLIFAMILVSISICVTVVVLNVHFRSPQTHKMAPWVK 329          

Query:  198 TGFKSAVQLYQKLLDENNYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLYN 491
             G   A +LY  LL  +NYNKL+RPV    D +     LKL+QLID+N+++Q +TTN+WV+Q W D  LRW P++Y GV +LH+PS+ IW PDIVLYN
Sbjct:    7 AGNPDAKRLYDDLL--SNYNKLVRPVVNTTDVLKVCIKLKLSQLIDVNLKNQIMTTNLWVEQSWYDYKLRWEPKEYGGVHMLHVPSDHIWRPDIVLYN 102          

Query: 1390 KINRTIADLKYVVDNLKDDDYKNKVQEEWRFVAVVMDRVFLLLFLSACVISTGSIILRSPALYDRRTPL 1596
            KI+++   ++++ ++ K  +   KV+E+W++VA+V+DR+FL +F  A V+ T  IIL++P LYD R P+
Sbjct:  451 KIHKSCFCVRFIAEHTKMQEDSTKVKEDWKYVAMVLDRLFLWIFTLAVVVGTAGIILQAPTLYDDRIPI 519          

Query:  475 ILFFTTHGKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHAVDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKYXXXXXXXXXXXXXXXXXXXXXXXRSTMTHSMSPWIRYXXXXXXXXXXXXHSPISKEKEMSERCFMYCNKTMFKEASASKLIYETFMRRSKRSYSLKD 1374
            +L+    G+Y V  MTKA + + G V WTPPA+++SSC I+V +FP+D Q C M F SWTY+  ++ LKH +QK   D+    G       +DLR +Y SVE+DIL + A RH + +   +E +P++ FNI +RRKTLFYTVNLI+PC+ +S+LSVLVFYLP  SGEKI+L I+ILLS T+FFLL+ E IPSTSL +PL+GKYLLFT++L+ LS++IT+I+LN+++R   TH M PWIR  F+                K + +   M   K + ++ +A+K+ Y     ++K   +L D
Sbjct:  132 VLYNNADGEYVVTTMTKAILHYTGKVVWTPPAIFKSSCEIDVRYFPFDQQTCFMKFGSWTYDGDQIDLKHISQKNDKDNKVEIG-------IDLREYYPSVEWDILGVPAERHEKYYPCCAEPYPDIFFNITLRRKTLFYTVNLIIPCVGISYLSVLVFYLPADSGEKIALCISILLSQTMFFLLISEIIPSTSLALPLLGKYLLFTMLLVGLSVVITIIILNIHYRKPSTHKMRPWIRSFFI----------------KRLPKLLLMRVPKDLLRDLAANKINYGLKFSKTKFGQALMD 408          

Query:  141 RFNKPLEXXXXXXXXXQTSTGFKSAVQLYQKLLDENNYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLYN 491
            R  KPL +++++ +L +T      A +LY  LL  +NYN+LIRPV  N D V    GL+L+QLIDLN++DQ LTTNVW++ EWQD   +W+P +Y GV  L++PS  IWLPDIVLYN
Sbjct:   21 RHCKPLCLLLVLLLLCETVQANPDAKRLYDDLL--SNYNRLIRPVSNNTDTVLVKLGLRLSQLIDLNLKDQILTTNVWLEHEWQDHKFKWDPSEYGGVTELYVPSEHIWLPDIVLYN 135          

Query: 1363 SLKDASIEEK----INRTIADLKYVVDNLKDDDYKNKVQEEWRFVAVVMDRVFLLLFLSACVISTGSIILRSPALYDRRTPLD 1599
            SL D +  +K    + + I ++ ++  +++  D  N   ++W FVA+VMDR+FL LF+ A ++ T  I+  +P+LYD    +D
Sbjct:  476 SLSDVAARKKYPFELEKAIHNVMFIQHHMQRQDEFNAEDQDWGFVAMVMDRLFLWLFMIASLVGTFVILGEAPSLYDDTKAID 558          

Query:  475 ILFFTTHGKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHAVDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKYXXXXXXXXXXXXXXXXXXXXXXXRSTMTHSMSPWIRYXXXXXXXXXXXXHSPISKEKEMSERCFMYCNKTMFKEASASKLIYETFMRRSKRSYSLKD 1374
            +L+    G+Y V  MTKA + + G V WTPPA+++SSC I+V +FP+D Q C M F SWTY+  ++ LKH +QK   D+    G       +DLR +Y SVE+DIL + A RH + +   +E +P++ FNI +RRKTLFYTVNLI+PC+ +S+LSVLVFYLP  SGEKI+L I+ILLS T+FFLL+ E IPSTSL +PL+GKYLLFT++L+ LS++IT+I+LN+++R   TH M PWIR  F+                K + +   M   K + ++ +A+K+ Y     ++K   +L D
Sbjct:  132 VLYNNADGEYVVTTMTKAILHYTGKVVWTPPAIFKSSCEIDVRYFPFDQQTCFMKFGSWTYDGDQIDLKHISQKNDKDNKVEIG-------IDLREYYPSVEWDILGVPAERHEKYYPCCAEPYPDIFFNITLRRKTLFYTVNLIIPCVGISYLSVLVFYLPADSGEKIALCISILLSQTMFFLLISEIIPSTSLALPLLGKYLLFTMLLVGLSVVITIIILNIHYRKPSTHKMRPWIRSFFI----------------KRLPKLLLMRVPKDLLRDLAANKINYGLKFSKTKFGQALMD 408          

Query:  141 RFNKPLEXXXXXXXXXQTSTGFKSAVQLYQKLLDENNYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLYN 491
            R  KPL +++++ +L +T      A +LY  LL  +NYN+LIRPV  N D V    GL+L+QLIDLN++DQ LTTNVW++ EWQD   +W+P +Y GV  L++PS  IWLPDIVLYN
Sbjct:   21 RHCKPLCLLLVLLLLCETVQANPDAKRLYDDLL--SNYNRLIRPVSNNTDTVLVKLGLRLSQLIDLNLKDQILTTNVWLEHEWQDHKFKWDPSEYGGVTELYVPSEHIWLPDIVLYN 135          

Query: 1363 SLKDASIEEK----INRTIADLKYVVDNLKDDDYKNKVQEEWRFVAVVMDRVFLLLFLSACVISTGSIILRSPALYDRRTPLD 1599
            SL D +  +K    + + I ++ ++  +++  D  N   ++W FVA+VMDR+FL LF+ A ++ T  I+  +P+LYD    +D
Sbjct:  476 SLSDVAARKKYPFELEKAIHNVMFIQHHMQRQDEFNAEDQDWGFVAMVMDRLFLWLFMIASLVGTFVILGEAPSLYDDTKAID 558          

Query:  475 ILFFTTHGKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHAVDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKYXXXXXXXXXXXXXXXXXXXXXXXRSTMT-HSMSPWIRYXXXXXXXXXXXXHSPISKEKEMSERCFMYCNKTMFK----EASASKLIYETFMRRSKRSYSLKDASIEEKIN---RTIADLKYVVDNLKDDDYKNKVQEEWRFVAVVMDRVFLLLFLSACVISTGSIILRSPAL 1575
            +L+    G++E  +MTKA V ++G + WTPPA Y+S+C ++V FFP+D QNC M F SWTY+ + + L                 V++NH VD  +F+ + E++I  LSA  H    +     +P +T++ I++R  LFYT+ LI+PCL +SFL+VLVFYLP+  GEK+SLS ++L+SLT+F L++ E IPS+S VIPLIG+YLLF +I ++LSII+TV V+NV+ RS+ T H MSPW+R +FL                + + +   M  N   +     E  +  L       RSK+     +   +  IN   +    ++Y+  ++K + +  +V ++W+FVA V+DR+FL  FL+  V+  G+I++ +PA+
Sbjct:  118 VLYENADGRFEGSIMTKAIVRYNGLITWTPPASYKSACTMDVTFFPFDRQNCSMKFGSWTYDGNMVEL-----------------VLVNHQVDRSDFFDNGEWEI--LSATGHKGSRRDGHYSYPYITYSFILKRLPLFYTLFLIIPCLGLSFLTVLVFYLPSDEGEKVSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLLFIMIFVTLSIIVTVFVINVHHRSSATYHPMSPWVRTLFL----------------QRLPDLLCMRGNTDRYHYPQMEPQSPDL-----KPRSKKGPPGPEGDGQALINMLEQATNSVRYISRHIKKEHFIREVVQDWKFVAQVLDRIFLWAFLTVSVL--GTILIFTPAV 450          

Query:  249 NYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLY 488
             Y + +RP+      V   FGLK++QL+D++ ++Q +TTNVW+ +EW D  LRWNPE+Y G+  + +PS  IWLPDIVLY
Sbjct:   41 GYQRWVRPILHANHTVKVRFGLKISQLVDVDEKNQLMTTNVWLYEEWLDYKLRWNPENYGGITFIRVPSESIWLPDIVLY 120          

Query:  475 ILFFTTHGKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHAVDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKYXXXXXXXXXXXXXXXXXXXXXXXRSTMTHSMSPWIR 1191
            +L+    G + V  +TKA+VF++G +KW PPA+Y+SSC I+V FFP+D QNC+M F SWTY+  K+ L                 + +   VD  +++ S E+ I+      +I++++  +E +P++T++ I+RR  LFYT+NLI+PCL +S L+VLVFYLP++  EKI+L I++LLSLT+F LL+ E IPSTSLVIPLIG+YLLFT+I ++LSIIITV VLNV+ RS+ THSM  W+R
Sbjct:  118 VLYNNADGDFAVTHLTKAQVFYNGRIKWKPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDRAKIDL-----------------ISMASDVDQMDYWESGEWVIINAVGTYNIKKYECCTEIYPDITYSFIIRRLPLFYTINLIIPCLLISCLTVLVFYLPSECAEKITLCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMIFVTLSIIITVFVLNVHHRSSRTHSMPHWVR 339          

Query:  249 NYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLYN 491
            NYNKL RPV    D V  +FGL + QLID++ ++Q +TTNVWV+QEW D  LRWNPE+YE V  + IPS  IW PDIVLYN
Sbjct:   41 NYNKLSRPVANISDVVLVHFGLSIAQLIDVDEKNQMMTTNVWVKQEWNDYKLRWNPEEYENVTSIRIPSEIIWRPDIVLYN 121          

Query: 1375 ASIEEKINRTIADLKYVVDNLKDDDYKNKVQEEWRFVAVVMDRVFLLLFLSACVISTGSIIL 1560
            +++ + + + +  ++Y+ D+L+ +D    V+E+W++VA+V+DR+FL +F+  C++ T  + L
Sbjct:  558 SNLSQSLLKALEGVQYIADHLRAEDSDFSVREDWKYVAMVIDRIFLWMFVLVCILGTVGLFL 619          

Query:  475 ILFFTTHGKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHAVDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKYXXXXXXXXXXXXXXXXXXXXXXXRSTMT-HSMSPWIR--YXXXXXXXXXXXXHSPISKEKEMSERCFMYCNKTMFKEASASKLIYETFMRRSKRSYSLKDASIEEKINRT-IADLK-------YVVDNLKDDDYKNKVQEEWRFVAVVMDRVFLLLFLSACVISTGSIILRSPAL 1575
            +L+    G++E  LMTKA V  +GT+ WTPPA Y+S+C ++V FFP+D QNC M F SWTY D  MV                   +++  VD ++F+ + E++IL  + +R  R+    S  +P +T++ I++R  LFYT+ LI+PCL +SFL+VLVFYLP+  GEK+SLS ++L+SLT+F L++ E IPS+S VIPLIG+YLLF +I ++ SII+TV V+NV+ RS+ T H M+PW++  ++        +  H+   +  ++  R               S  +     +  ++S     A ++E  N+  IA L+       Y+  +++ + +  +V ++W+FVA V+DR+FL  FL+  V+  G+I++ +PAL
Sbjct:  119 VLYENADGRFEGSLMTKAIVRFNGTIMWTPPASYKSACTMDVTFFPFDRQNCSMKFGSWTY-DGTMV----------------DLTLVDAYVDRKDFFDNGEWEILNATGQRGSRRDGIYS--YPYLTYSFILKRLPLFYTLFLIIPCLGLSFLTVLVFYLPSDEGEKLSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLLFIMIFVTFSIIVTVFVINVHHRSSATYHPMAPWVKSLFLQRLPRLLCMRGHTDRYQYPDIELR---------------SPELKRGMKKGQQKSAGGGRAGVKEDENQAWIALLEKATHSVHYISRHIRKEHFIREVVQDWKFVAQVLDRIFLWAFLTVSVL--GTILIFTPAL 460          

Query:  246 NNYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLY 488
              Y K +RPV    D +T  FGLK++QL+D++ ++Q +TTNVW+ +EW D  LRWNPEDY G+  + +PS  IWLPDIVLY
Sbjct:   41 RGYQKWVRPVLHANDTITVRFGLKISQLVDVDEKNQLMTTNVWLWEEWTDYKLRWNPEDYGGITSIRVPSETIWLPDIVLY 121          

Query:  475 ILFFTTHGKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHAVDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKYXXXXXXXXXXXXXXXXXXXXXXXRSTMT-HSMSPWIR--YXXXXXXXXXXXXHSPISKEKEMSERCFMYCNKTMFKEASASKLIYETFMRRSKRSYSLKDASIEEKINRT-IADLK-------YVVDNLKDDDYKNKVQEEWRFVAVVMDRVFLLLFLSACVISTGSIILRSPAL 1575
            +L+    G++E  LMTKA V  +GT+ WTPPA Y+S+C ++V FFP+D QNC M F SWTY D  MV                   +++  VD ++F+ + E++IL  + +R  R+    S  +P +T++ I++R  LFYT+ LI+PCL +SFL+VLVFYLP+  GEK+SLS ++L+SLT+F L++ E IPS+S VIPLIG+YLLF +I ++ SII+TV V+NV+ RS+ T H M+PW++  ++        +  H+   +  ++  R               S  +     +  ++S     A ++E  N+  IA L+       Y+  +++ + +  +V ++W+FVA V+DR+FL  FL+  V+  G+I++ +PAL
Sbjct:  111 VLYENADGRFEGSLMTKAIVRFNGTIMWTPPASYKSACTMDVTFFPFDRQNCSMKFGSWTY-DGTMV----------------DLTLVDAYVDRKDFFDNGEWEILNATGQRGSRRDGIYS--YPYLTYSFILKRLPLFYTLFLIIPCLGLSFLTVLVFYLPSDEGEKLSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLLFIMIFVTFSIIVTVFVINVHHRSSATYHPMAPWVKSLFLQRLPRLLCMRGHTDRYQYPDIELR---------------SPELKRGMKKGQQKSAGGGRAGVKEDENQAWIALLEKATHSVHYISRHIRKEHFIREVVQDWKFVAQVLDRIFLWAFLTVSVL--GTILIFTPAL 452          

Query:  246 NNYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLY 488
              Y K +RPV    D +T  FGLK++QL+D++ ++Q +TTNVW+ +EW D  LRWNPEDY G+  + +PS  IWLPDIVLY
Sbjct:   33 RGYQKWVRPVLHANDTITVRFGLKISQLVDVDEKNQLMTTNVWLWEEWTDYKLRWNPEDYGGITSIRVPSETIWLPDIVLY 113          

Query:  475 ILFFTTHGKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHAVDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKYXXXXXXXXXXXXXXXXXXXXXXXRSTMTHSMSPWI 1188
            +L+    G++ V  MTKA +FH G V+W PPA+Y+SSC I+V FFP+D QNC+M F SWTY+  K+ L+                  I + VDL++++ S E+ I+      + +++    E +P++T+  I+RR  LFYT+NLI+PCL +S L+VLVFYLP+  GEKI+L I++LLSLT+F LL+ E IPSTSLVIPLIG+YLLFT+I ++LSI+ITV VLNV+ RS  TH M  W+
Sbjct:  122 VLYNNADGEFAVTHMTKAHLFHTGKVRWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLER-----------------IENTVDLKDYWESGEWAIINAVGTYNTKKYDCCHEIYPDITYFFIIRRLPLFYTINLIIPCLLISCLTVLVFYLPSDCGEKITLCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPSTHKMPCWV 342          

Query:  219 QLYQKLLDENNYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLYN 491
            +L++KL D   YNK  RPV    D V   FGL + QLID++ ++Q +TTNVW++QEW D  LRW P DY+ V  + +PS  IW+PDIVLYN
Sbjct:   37 ELFKKLFD--GYNKWSRPVPNTSDVVIVKFGLSIAQLIDVDEKNQMMTTNVWLKQEWNDYKLRWKPSDYDNVTSIRVPSELIWVPDIVLYN 125          

Query: 1381 IEEKINRTIADLKYVVDNLKDDDYKNKVQEEWRFVAVVMDRVFLLLFLSACVISTGSIIL 1560
            +   + + +  + Y+ D+L+ +D    V+E+W++VA+V+DR+FL +F+  C++ T  + L
Sbjct:  483 LSPSVLQALEGVHYIADHLRAEDADFSVKEDWKYVAMVIDRIFLWMFIIVCLLGTIGLFL 542          

Query:  475 ILFFTTHGKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHA-VDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKYXXXXXXXXXXXXXXXXXXXXXXXRSTMTHSMSPWIRYXXXXXXXXXXXXHSPISKEKEMSERCFM-------YCNKTMFKEASASK------------LIYETFMRRSKRSYSLKDASIEEKINRTIADLKYVVDNLKDDDYKNKVQEEWRFVAVVMDRVFLLLFLSACVISTGSIILRSPALYDRRTPLDGNHLP 1614
            +L+    G YEV L T A V ++G+V W PPA+Y+S+C I V+ FP+D QNC + F SWTY+        YT+  +          V+N     + +F  S E+DI+EL  RR I         + +VT++ I++RK LFYT+NLI+PC+ ++ L++LVFYLP+  G+K++L I++LL+LT+F LL+ + +P TSL +PLIGKYL+FT++L++ SI+ +V VLNV+ RS  TH+M PW++  FL  LP  LF+  P +       R +        + N   F   + ++            + ++ F  R  R Y+        +++  +  +K++ +++K +D    + E+W++VA+V+DR+FL +F+  C++ T  + ++         PL  NH P
Sbjct:  129 VLYNNADGTYEVSLFTNAIVQNNGSVAWLPPAIYKSACKIEVKHFPFDQQNCTLKFRSWTYD--------YTEIDL----------VLNKGWATMDDFTPSGEWDIIELPGRRTICPLD---PTYVDVTYDFIIKRKPLFYTINLIIPCILITSLAILVFYLPSDCGQKMTLCISVLLALTVFLLLISKIVPPTSLDVPLIGKYLMFTMVLVTFSIVTSVCVLNVHHRSPSTHTMPPWVKNCFLDRLPVFLFMKRPENSSASQKLRSYRRNMQIESFRNSNYFVNMTTARPCDHTVNDPPESVRHQEFRYRYPRKYT-------PEVHEAMDGVKFISEHMKSEDEDQSIIEDWKYVAMVVDRLFLWIFIIVCIVGTVGLFMQ---------PLIQNHTP 491          

Query:  192 TSTGFKSA---VQLYQKLLDENNYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLYN 491
             S G K+A    +L   LL ++ YNKLIRP   N   V+    L L QLI +N R+Q +TTNVW+ QEW D  L WNP DY+G++ L IPS +IWLPDIVLYN
Sbjct:   30 CSLGCKAADSEERLMNNLLRKDKYNKLIRPAYNNSQLVSIQLQLSLAQLISVNEREQIMTTNVWLNQEWVDYRLTWNPADYDGIKKLRIPSQQIWLPDIVLYN 132          

Query:  475 ILFFTTHGKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHA-VDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKYXXXXXXXXXXXXXXXXXXXXXXXRSTMTHSMSPWIRYXXXXXXXXXXXXHSPISKEKEMSERCFM-------YCNKTMFKEASASK------------LIYETFMRRSKRSYSLKDASIEEKINRTIADLKYVVDNLKDDDYKNKVQEEWRFVAVVMDRVFLLLFLSACVISTGSIILRSPALYDRRTPLDGNHLP 1614
            +L+    G YEV L T A V ++G+V W PPA+Y+S+C I V+ FP+D QNC + F SWTY+        YT+  +          V+N     + +F  S E+DI+EL  RR I         + +VT++ I++RK LFYT+NLI+PC+ ++ L++LVFYLP+  G+K++L I++LL+LT+F LL+ + +P TSL +PLIGKYL+FT++L++ SI+ +V VLNV+ RS  TH+M PW++  FL  LP  LF+  P +       R +        + N   F   + ++            + ++ F  R  R Y+        +++  +  +K++ +++K +D    + E+W++VA+V+DR+FL +F+  C++ T  + ++         PL  NH P
Sbjct:   99 VLYNNADGTYEVSLFTNAIVQNNGSVAWLPPAIYKSACKIEVKHFPFDQQNCTLKFRSWTYD--------YTEIDL----------VLNKGWATMDDFTPSGEWDIIELPGRRTICPL---DPTYVDVTYDFIIKRKPLFYTINLIIPCILITSLAILVFYLPSDCGQKMTLCISVLLALTVFLLLISKIVPPTSLDVPLIGKYLMFTMVLVTFSIVTSVCVLNVHHRSPSTHTMPPWVKNCFLDRLPVFLFMKRPENSSASQKLRSYRRNMQIESFRNSNYFVNMTTARPCDHTVNDPPESVRHQEFRYRYPRKYT-------PEVHEAMDGVKFISEHMKSEDEDQSIIEDWKYVAMVVDRLFLWIFIIVCIVGTVGLFMQ---------PLIQNHTP 461          

Query:  201 GFKSA---VQLYQKLLDENNYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLYN 491
            G K+A    +L   LL ++ YNKLIRP   N   V+    L L QLI +N R+Q +TTNVW+ QEW D  L WNP DY+G++ L IPS +IWLPDIVLYN
Sbjct:    3 GCKAADSEERLMNNLLRKDKYNKLIRPAYNNSQLVSIQLQLSLAQLISVNEREQIMTTNVWLNQEWVDYRLTWNPADYDGIKKLRIPSQQIWLPDIVLYN 102          

Query:  475 ILFFTTHGKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHA-VDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKYXXXXXXXXXXXXXXXXXXXXXXXRSTMTHSMSPWIRYXXXXXXXXXXXXHSPISKEKEMSERCFM-------YCNKTMFKEASASK------------LIYETFMRRSKRSYSLKDASIEEKINRTIADLKYVVDNLKDDDYKNKVQEEWRFVAVVMDRVFLLLFLSACVISTGSIILRSPALYDRRTPLDGNHLP 1614
            +L+    G YEV L T A V ++G+V W PPA+Y+S+C I V+ FP+D QNC + F SWTY+        YT+  +          V+N     + +F  S E+DI+EL  RR I         + +VT++ I++RK LFYT+NLI+PC+ ++ L++LVFYLP+  G+K++L I++LL+LT+F LL+ + +P TSL +PLIGKYL+FT++L++ SI+ +V VLNV+ RS  TH+M PW++  FL  LP  LF+  P +       R +        + N   F   + ++            + ++ F  R  R Y+        +++  +  +K++ +++K +D    + E+W++VA+V+DR+FL +F+  C++ T  + ++         PL  NH P
Sbjct:  117 VLYNNADGTYEVSLFTNAIVQNNGSVAWLPPAIYKSACKIEVKHFPFDQQNCTLKFRSWTYD--------YTEIDL----------VLNKGWATMDDFTPSGEWDIIELPGRRTICPL---DPTYVDVTYDFIIKRKPLFYTINLIIPCILITSLAILVFYLPSDCGQKMTLCISVLLALTVFLLLISKIVPPTSLDVPLIGKYLMFTMVLVTFSIVTSVCVLNVHHRSPSTHTMPPWVKNCFLDRLPVFLFMKRPENSSASQKLRSYRRNMQIESFRNSNYFVNMTTARPCDHTVNDPPESVRHQEFRYRYPRKYT-------PEVHEAMDGVKFISEHMKSEDEDQSIIEDWKYVAMVVDRLFLWIFIIVCIVGTVGLFMQ---------PLIQNHTP 479          

Query:  210 SAVQLYQKLLDENNYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLYN 491
            S  +L   LL ++ YNKLIRP   N   V+    L L QLI +N R+Q +TTNVW+ QEW D  L WNP DY+G++ L IPS +IWLPDIVLYN
Sbjct:   27 SEERLMNNLLRKDKYNKLIRPAYNNSQLVSIQLQLSLAQLISVNEREQIMTTNVWLNQEWVDYRLTWNPADYDGIKKLRIPSQQIWLPDIVLYN 120          

Query:  475 ILFFTTHGKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHA-VDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKYXXXXXXXXXXXXXXXXXXXXXXXRSTMTHSMSPWIRYXXXXXXXXXXXXHSPISKEKEMSERCFM-------YCNKTMFKEASASK------------LIYETFMRRSKRSYSLKDASIEEKINRTIADLKYVVDNLKDDDYKNKVQEEWRFVAVVMDRVFLLLFLSACVISTGSIILRS 1566
            +L+    G YEV L T A V ++G+V W PPA+Y+S+C I V+ FP+D QNC + F SWTY+        YT+  +          V+N     + +F  S E+DI+EL  RR I         + +VT++ I++RK LFYT+NLI+PC+ ++ L++LVFYLP+  G+K++L I++LL+LT+F LL+ + +P TSL +PLIGKYL+FT++L++ SI+ +V VLNV+ RS  TH+M PW++  FL  LP  LF+  P +       R +        + N   F   + ++            + ++ F  R  R Y+        +++  +  +K++ +++K +D    + E+W++VA+V+DR+FL +F+  C++ T  + +++
Sbjct:  137 VLYNNADGTYEVSLFTNAIVQNNGSVAWLPPAIYKSACKIEVKHFPFDQQNCTLKFRSWTYD--------YTEIDL----------VLNKGWATMDDFTPSGEWDIIELPGRRTICPL---DPTYVDVTYDFIIKRKPLFYTINLIIPCILITSLAILVFYLPSDCGQKMTLCISVLLALTVFLLLISKIVPPTSLDVPLIGKYLMFTMVLVTFSIVTSVCVLNVHHRSPSTHTMPPWVKNCFLDRLPVFLFMKRPENSSASQKLRSYRRNMQIESFRNSNYFVNMTTARPCDHTVNDPPESVRHQEFRYRYPRKYT-------PEVHEAMDGVKFISEHMKSEDEDQSIIEDWKYVAMVVDRLFLWIFIIVCIVGTVGLFMQA 492          

Query:  192 TSTGFKSA---VQLYQKLLDENNYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLYN 491
             S G K+A    +L   LL ++ YNKLIRP   N   V+    L L QLI +N R+Q +TTNVW+ QEW D  L WNP DY+G++ L IPS +IWLPDIVLYN
Sbjct:   38 CSLGCKAADSEERLMNNLLRKDKYNKLIRPAYNNSQLVSIQLQLSLAQLISVNEREQIMTTNVWLNQEWVDYRLTWNPADYDGIKKLRIPSQQIWLPDIVLYN 140          

Query:  475 ILFFTTHGKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHAVDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKYXXXXXXXXXXXXXXXXXXXXXXXRSTMTHSMSPWIRYXXXXXXXXXXXXHSPISK---------------------EKEMSERCFMYCNKTMFKE--ASASKLIYETFMRRSKRSYSLKDASIEEKINRTIADLKYVVDNLKDDDYKNKVQEEWRFVAVVMDRVFLLLFLSACVISTGSIILR 1563
            +L+    G YEV   + A V HDG++ W PPA+Y+S+C I V+ FP+D QNC M F SWTY+  ++ L                 V+ +    L +F  S E+DI+ L  RR+          + ++T++ I+RRK LFYT+NLI+PC+ ++ L++LVFYLP+  GEK++L I++LL+LT+F LL+ + +P TSL +PL+GKYL+FT++L++ SI+ +V VLNV+ RS  TH+M PW++ +FL  LP +LF+  P                         ++ +  C  Y N+   K+  A  S+L       R ++    K       +   +  ++++ D++K +D    V E+W++VA+V+DR+FL +F+  CV  T  + L+
Sbjct:  118 VLYNNADGMYEVSFYSNAVVSHDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRSWTYDRTELDL-----------------VLRSDVASLDDFTPSGEWDIIALPGRRNENP---NDSTYVDITYDFIIRRKPLFYTINLIIPCILITSLAILVFYLPSDCGEKMTLCISVLLALTVFLLLISKIVPPTSLDVPLVGKYLMFTMVLVTFSIVTSVCVLNVHHRSPTTHTMPPWVKVVFLDKLPTLLFMKQPRQNCARQRLRQQRQSQERAAGSFFLRDGARSCTCYVNQASVKKYGAQLSELPEGVNGFRDRQG---KVRQCLCGLQEAVDGVRFIADHMKSEDDDQSVSEDWKYVAMVIDRLFLWIFVFVCVFGTIGMFLQ 480          

Query:  192 TSTGFKSAVQLYQKLLDENNYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLYN 491
            +  G  +  +L + LLD + YNKLIRP     + VT    + L QLI ++ R+Q +TTNVW+ QEW+D  L W+P +++ ++ + +PS  IWLPD+VLYN
Sbjct:   22 SCLGTDTEERLVEHLLDPSRYNKLIRPATNGSEQVTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWDPAEFDDMKKVRLPSKHIWLPDVVLYN 121          

Query:  475 ILFFTTHGKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHAVDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKYXXXXXXXXXXXXXXXXXXXXXXXRSTMTHSMSPWIRYXXXXXXXXXXXXHSPISKEKEMS-----ERCFMYCNKTMFKEASASKLIYETF-----------MRRSKRS---YSLKDASIEEKINRTIADLKYVVDNLKDDDYKNKVQEEWRFVAVVMDRVFLLLFLSACVISTGSIILRSPALYDRRTPLDGN 1605
            +L+    G ++V+  TKA + +DG + WTPPA+++SSC +++ FFP+D QNC + F SWTY+  ++ L                 ++I   VD+ +F+ + E++I++ S  +H  ++    E + ++T++  +RR  +FYT+NLI+PCL +SFL+VLVFYLP+  GEK++L I++LLSLT+F L++ ETIPSTSLVIPL+G+YLLFT+I ++LSI++TV VLN+++R+  TH+M  W++ IFL+  P IL +  P+ K KE       +       K  F     SKL+ E              RRS +    +  +++     +   I  ++++ +N+K  +  N+V+++W+++A+V+DRVFL +F+  CV  T  + L+         PL GN
Sbjct:  121 VLYNNAVGDFQVEGKTKALLKYDGVITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDL-----------------LIIGSKVDMNDFWENSEWEIVDASGYKHDIKYNCCEEIYTDITYSFYIRRLPMFYTINLIIPCLFISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLVGEYLLFTMIFVTLSIVVTVFVLNIHYRTPATHTMPKWVKTIFLQAFPSILMMRKPLDKTKEAGGVKDPKSHTKRPAKVKFTHRGESKLLKECHHCQKSSDIAPGKRRSSQQPARWVAENSEHSSDVEDVIESVQFIAENMKSHNETNEVEDDWKYMAMVVDRVFLWVFIIVCVFGTVGLFLQ---------PLLGN 490          

Query:  189 QTSTGFKSAVQLYQKLLDENNYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLYN 491
            + STG +S  QL+ +L    +YN+ IRPVE   D VT +F L +TQL +++  +Q + TN+W++  W+D  LRW+P +Y+G++ L +P++ IW PDIVLYN
Sbjct:   26 KGSTGCESEEQLFHRLF--AHYNRFIRPVENVSDPVTVHFELAITQLANVDEVNQIMETNLWLRHIWKDYRLRWDPTEYDGIETLRVPADNIWKPDIVLYN 124          

Query:  475 ILFFTTHGKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHAVDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKYXXXXXXXXXXXXXXXXXXXXXXXRSTMTHSMSPWIRYXXXXXXXXXXXXHSPISK------------------EKEMSER-------------------CFMYCNKTMFKEASASKLIYETFMRRSKRSYSLKDASIEEKINRTIADLKYVVDNLKDDDYKNKVQEEWRFVAVVMDRVFLLLFLSACVISTGSIIL 1560
            +L+    G++ V  MTKA +F  GTV W PPA+Y+SSC I+V FFP+D QNC+M F SWTY+  K+ L+                  +   VDL++++ S E+ I+  +   + +++   +E +P+VT+  ++RR  LFYT+NLI+PCL +S L+VLVFYLP++ GEKI+L I++LLSLT+F LL+ E IPSTSLVIPLIG+YLLFT+I ++LSI+ITV VLNV+ RS  TH+M  W+R   L  +P  L ++ P+                    E  M                      C    + +M        L        +K      +  +  +I + +  + Y+ D+L+ +D  + V+E+W++VA+V+DR+FL LF+  C + T  + L
Sbjct:  123 VLYNNADGEFAVTHMTKAHLFFTGTVHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLEQ-----------------MERTVDLKDYWESGEWAIINATGTYNSKKYDCCAEIYPDVTYYFVIRRLPLFYTINLIIPCLLISCLTVLVFYLPSECGEKITLCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPSTHNMPNWVRVALLGRVPRWLMMNRPLPPMELHGSPGLKLSPTYHWLETNMDAEEREETEEEEEEEEDENICMCAGLPDSSMGVLYGHGSLHLRAMGPEAKTPSQASEILLSPQIQKALEGVHYIADHLRSEDADSSVKEDWKYVAMVVDRIFLWLFIIVCFLGTIGLFL 504          

Query:  219 QLYQKLLDENNYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLYN 491
            +L++ L     YN+  RPV    D V   FGL + QLID++ ++Q +TTNVW++QEW D  LRW+P ++  +  L +PS  IW+PDIVLYN
Sbjct:   38 RLFKHLF--GGYNRWARPVPNTSDVVIVRFGLSIAQLIDVDEKNQMMTTNVWLKQEWNDYKLRWDPAEFGNITSLRVPSEMIWIPDIVLYN 126          

Query:  475 ILFFTTHGKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHAVDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKYXXXXXXXXXXXXXXXXXXXXXXXRSTMTHSMSPWIRYXXXXXXXXXXXXHSPISK------------------EKEMSER-------------------CFMYCNKTMFKEASASKLIYETFMRRSKRSYSLKDASIEEKINRTIADLKYVVDNLKDDDYKNKVQEEWRFVAVVMDRVFLLLFLSACVISTGSIIL 1560
            +L+    G++ V  MTKA +F  GTV W PPA+Y+SSC I+V FFP+D QNC+M F SWTY+  K+ L+                  +   VDL++++ S E+ I+  +   + +++   +E +P+VT+  ++RR  LFYT+NLI+PCL +S L+VLVFYLP++ GEKI+L I++LLSLT+F LL+ E IPSTSLVIPLIG+YLLFT+I ++LSI+ITV VLNV+ RS  TH+M  W+R   L  +P  L ++ P+                    E  M                      C    + +M        L        +K      +  +  +I + +  + Y+ D+L+ +D  + V+E+W++VA+V+DR+FL LF+  C + T  + L
Sbjct:  123 VLYNNADGEFAVTHMTKAHLFFTGTVHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLEQ-----------------MERTVDLKDYWESGEWAIINATGTYNSKKYDCCAEIYPDVTYYFVIRRLPLFYTINLIIPCLLISCLTVLVFYLPSECGEKITLCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPSTHNMPNWVRVALLGRVPRWLMMNRPLPPMELHGSPGLKLSPTYHWLETNMDAEEREETEEEEEEEEDENICMCAGLPDSSMGVLYGHGSLHLRAMGPEAKTPSQASEILLSPQIQKALEGVHYIADHLRSEDADSSVKEDWKYVAMVVDRIFLWLFIIVCFLGTIGLFL 504          

Query:  219 QLYQKLLDENNYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLYN 491
            +L++ L     YN+  RPV    D V   FGL + QLID++ ++Q +TTNVW++QEW D  LRW+P ++  +  L +PS  IW+PDIVLYN
Sbjct:   38 RLFKHLF--GGYNRWARPVPNTSDVVIVRFGLSIAQLIDVDEKNQMMTTNVWLKQEWNDYKLRWDPAEFGNITSLRVPSEMIWIPDIVLYN 126          

Query:  475 ILFFTTHGKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHAVDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKYXXXXXXXXXXXXXXXXXXXXXXXRSTMT-HSMSPWIRYXXXXXXXXXXXXHSPISKEKEMSERCFMYCNKTMFKEASASKLIYETFMRRSKRSYSLKDAS--IEEKINRTIADLKYVVDNLKDDDYKNKVQEEWRFVAVVMDRVFLLLFLSACVISTGSIILRSPAL 1575
            +LF    G++E  LMTKA V   GTV WTPPA Y+SSC ++V FFP+D QNC M F SWTY D  MV                  ++IN  VD ++F+ + E++IL     +  R+    S  +P VT++ ++RR  LFYT+ LI+PCL +SFL+VLVFYLP+  GEK+SLS ++L+SLT+F L++ E IPS+S VIPLIG+YLLF +I ++LSII+TV V+NV+ RS+ T H M+PW++ +FL+ LP  L +  P               ++  F + + SK          K+     D    +   + +    ++Y+  ++K + + ++V ++W+FVA V+DR+FL LFL+A V+  GS+++  PAL
Sbjct:  122 VLFENADGRFEGSLMTKAIVKSSGTVSWTPPASYKSSCTMDVTFFPFDKQNCSMKFGSWTY-DGTMV----------------DLILINENVDRKDFFDNGEWEILNAKGMKGNRREGFYS--YPFVTYSFVLRRLPLFYTLFLIIPCLGLSFLTVLVFYLPSDEGEKLSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLLFIMIFVTLSIIVTVFVINVHHRSSSTYHPMAPWVKRLFLEKLPRWLCMKDP--------------RDRFSFPDGTESKGTVRGKFPGKKKQTPTSDGERVLVAFLEKASESIRYISRHVKKEHFISQVVQDWKFVAQVLDRIFLWLFLTASVL--GSVLIFIPAL 456          

Query:  192 TSTGFKSAVQLYQKLLDE--NNYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLY 488
             + G  S  +    LL      Y K +RPV  + D +  YFGLK++QL+D++ ++Q +TTNVW++QEW D  LRWNPEDY G+  + +PS  +WLPDIVL+
Sbjct:   24 ATAGLSSVAEHEDALLRHLFQGYQKCVRPVLNSSDIIKVYFGLKISQLVDVDEKNQLMTTNVWLKQEWTDQKLRWNPEDYGGINSIKVPSESLWLPDIVLF 124          

Query:  475 ILFFTTHGKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHAVDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKYXXXXXXXXXXXXXXXXXXXXXXXRSTMTHSMSPWIRYXXXXXXXXXXXXHSP------------------------ISKEKEMSERCFMYCNKTMFKEASASKLIYETFMRRSKRSYSLKDASIEEKINRTIADLKYVVDNLKDDDYKNKVQEEWRFVAVVMDRVFLLLFLSACVISTGSIILR 1563
            +L+    G YEV   + A V +DG++ W PPA+Y+S+C I V+ FP+D QNC M F SWTY+  ++ L                 V+ +    L +F  S E+DI+ L  RR+      +   + ++T++ I+RRK LFYT+NLI+PC+ ++ L++LVFYLP+  GEK++L I++LL+LT+F LL+ + +P TSL +PL+GKYL+FT++L++ SI+ +V VLNV+ RS  TH+M+PW++ +FL+ LP +LFL  P                          +E   ++ C  + N     +  A     E       RS       + E ++     ++++ D+++ +D    V+E+W++VA+V+DR+FL +F+  CV  T  + L+
Sbjct:  118 VLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRSWTYDRTEIDL-----------------VLKSDVASLDDFTPSGEWDIIALPGRRNENP---DDSTYVDITYDFIIRRKPLFYTINLIIPCVLITSLAILVFYLPSDCGEKMTLCISVLLALTVFLLLISKIVPPTSLDVPLVGKYLMFTMVLVTFSIVTSVCVLNVHHRSPTTHTMAPWVKVVFLEKLPTLLFLQQPRHRCARQRLRLRRRQREREGAGTLFFREGPAADPCTCFVNPASM-QGLAGAFQAEPAAAGLGRSMGPCSCGLREAVD----GVRFIADHMRSEDDDQSVREDWKYVAMVIDRLFLWIFVFVCVFGTIGMFLQ 479          

Query:  219 QLYQKLLDENNYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLYN 491
            +L + LLD + YNKLIRP     + VT    + L QLI ++ R+Q +TTNVW+ QEW+D  L W PED++ ++ + +PS  IWLPD+VLYN
Sbjct:   31 RLVEHLLDPSRYNKLIRPATNGSELVTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEDFDNMKKVRLPSKHIWLPDVVLYN 121          

Query:  475 ILFFTTHGKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHAVDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKYXXXXXXXXXXXXXXXXXXXXXXXRSTMTHSMSPWIR-----YXXXXXXXXXXXXHSPISKE--------KEMSERCFMYCNKTMFKEASASKLIYETFMRRSKRSYSLKDASIEEKINRTIADLKYVVDNLKDDDYKNKVQEEWRFVAVVMDRVFLLLFLSACVISTGSIILRSPALYDRRTPLD 1599
            +L+    G YEV LMTKA + + G V W PPA+Y+SSC +NVE+FPYD Q C M F SWTYN  ++ LKH  Q  IP      G+ ++   +DL  FY SVE+DILE+ A ++   +    E F ++TF + MRRKTLFYTVNLI+PC+A++FL+VLVFYLP+ SGEK++L I+IL+SLT+FFLLL E IP TSL +PL+GKYLLFT+IL+SLS+  TV VLN++FRS  TH+MSP +R     ++    +        P   +         E+  R  +    + FK++      Y+  M+ S  S ++   ++  ++ + +  ++++  ++KD D  N++ E+W+FV++V+DR FL LF  +CV  T +II +SP+LYD R+P+D
Sbjct:  117 VLYNNWDGNYEVTLMTKATLKYTGEVFWEPPAIYKSSCEMNVEYFPYDEQICFMKFGSWTYNGAQVDLKHLDQ--IP------GSNLVQVGIDLTEFYLSVEWDILEVPATKNEEYYPDTLEPFSDITFKLTMRRKTLFYTVNLIVPCVALTFLTVLVFYLPSDSGEKVTLCISILVSLTVFFLLLAEIIPPTSLAVPLLGKYLLFTMILVSLSVWTTVCVLNIHFRSPSTHNMSPLVRKLFLHFMPKLMMMRRTQYTLPDYDDSTPSNGYTNEIDVRDSISDFPSEFKDSQDGA--YDNGMQNSVDSDNVIPRNLTPEVLQALRAVRFIAQHIKDADKDNEIVEDWKFVSMVLDRFFLWLFTLSCVFGTLAIICQSPSLYDTRSPID 494          

Query:  219 QLYQKLLDENNYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLYNTW 497
            +LY  LL  +NYN+LIRPV  N + +T + GLKL+QLI++N+++Q +TTN+WV+Q W D  LRW+PE+Y GV+ L++PS  IW+PDIVLYN W
Sbjct:   32 RLYDDLL--SNYNRLIRPVVNNTETLTVWLGLKLSQLIEVNLKNQVMTTNLWVKQRWFDYKLRWDPEEYGGVEQLYVPSEHIWVPDIVLYNNW 122          

Query:  475 ILFFTTHGKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHAVDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKYXXXXXXXXXXXXXXXXXXXXXXXRSTMTHSMSPWIRYXXXXXXXXXXXXHSPISKEKEMSERCFMYCNK----TMFKEASASKLIYETFMRRSKRSY---------------SLKDASIEEKINRTIADLKYVVDNLKDDDYKNKVQEEWRFVAVVMDRVFLLLFLSACVISTGSIILRSPALYDRRTPLD 1599
            +L+    G +EV L TKA + + G V+W PPA+Y+SSC I+VE+FP+D Q C M F SWTY+  ++ L+H  +          GT V+   VDL  FYTSVE+DILE+ A R+ + +    E + ++TFNI MRRKTLFYTVNLI+PC+ +SFL+VLVFYLP+ SGEK+SLSI+ILLSLT+FFLLL E IP TSLV+PL+GK++LFT+IL + SI +TV+VLNV+FRS  TH+MSPW+R +F+  LP +L +  P  +      R           T++ E S            +                   +L+      ++++ I  + Y+ D  + ++   +V+E+W++VA+V+DR FL +F  A V+ +  IIL++P LYD R P+D
Sbjct:  112 VLYNNADGNFEVTLATKATLNYTGRVEWRPPAIYKSSCEIDVEYFPFDQQTCVMKFGSWTYDGFQVDLRHIDE--------VRGTNVVELGVDLSEFYTSVEWDILEVPAVRNEKFYTCCDEPYLDITFNITMRRKTLFYTVNLIIPCMGISFLTVLVFYLPSDSGEKVSLSISILLSLTVFFLLLAEIIPPTSLVVPLLGKFVLFTMILDTFSICVTVVVLNVHFRSPQTHTMSPWVRRVFIHVLPRLLVMRRPHYRLDPHRSRFAGLVTGAGETTLWDEGSPGVPAPPRPPPCAPPLAPCAACAPAEAPALCDALRRWHRCPELHKAIDGINYIADQTRKEEESTRVKEDWKYVAMVLDRPFLWIFTLAVVVGSAGIILQAPTLYDERAPID 497          

Query:  195 STGFKSAVQLYQKLLDENNYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLYN 491
              G   A +LY  LL  +NYNKL+RPV    DA+T    LKL+QLID+N+++Q +TTN+WV+Q W D  L W P +Y GV++LH+PS+ IW PDIVLYN
Sbjct:   19 CAGNPDAKRLYDDLL--SNYNKLVRPVLNVSDALTVRIKLKLSQLIDVNLKNQIMTTNLWVEQSWYDYKLSWEPREYGGVEMLHVPSDHIWRPDIVLYN 115          

Query:  475 ILFFTTHGKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKH---YTQKGI-PDSSNTSGTV-----VINHAVDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKYXXXXXXXXXXXXXXXXXXXXXXXRSTMTHSMSPWIRYXXXXXXXXXXXXHSP------ISKEKEMSERCFMYCNKTMFKEASASKLIYETF-MRRSKRSYSL-KDASIEEKINRTIADLKYVVDNLKDDDYKNKVQEEWRFVAVVMDRVFLLLFLSACVISTGSIILRSPALYDRRTPL 1596
            +L+    G Y+V +MTKAK+ ++GTV+W PPA+Y+S C I+VEFFP+D Q C+M F SWTY   ++ L+H   + +K I  D     G       V++  +DL ++Y SVE+DIL +  +RH +++      F ++T+ I +RRKTLFYTVNLI P + +SFL+ LVFYLP+  GEKISL I+IL+SLT+FFLLLVE IPSTSLVIPLIGKYLLFT++L++LS+++TV+ LNV++RS  TH+M  W++ +F+ FLP  L +  P          ++   R   +           S+L+       R + S++L +D S    +   +  + Y+ D+LK+++   +V E+W++++VVMDR+FL+ F  AC   T  II R+P++YD    L
Sbjct:  114 VLYNNADGNYQVTIMTKAKLTYNGTVEWAPPAIYKSMCQIDVEFFPFDRQQCEMKFGSWTYGGLEVDLQHRDKHLEKEIEEDVEGVDGPTKEIVWVVDRGIDLSDYYPSVEWDILNVPGKRHSKRYPCCESPFIDITYEIHLRRKTLFYTVNLIFPSVGISFLTALVFYLPSDGGEKISLCISILISLTVFFLLLVEIIPSTSLVIPLIGKYLLFTMVLVTLSVVVTVVTLNVHYRSPTTHTMPKWMKRLFVDFLPKYLLMTRPQPPGHHSKPNRKFDSRASTFSIGVNHVLGQNSELLSPGLNSNREESSFTLPRDNS---PVRSAVESVAYIADHLKNEEDDKQVIEDWKYISVVMDRIFLITFTFACAFGTVVIIARAPSIYDNTPAL 501          

Query:  207 KSAVQLYQKLLDENNYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLYN 491
            + A +L++ L+   +YNKL+RPV  N + +   F LKL+QL+D++ ++Q +TTNVW+Q  W D  LRW+P +Y GV++L++PS+ IWLPD+VLYN
Sbjct:   25 RDANRLFEDLI--ADYNKLVRPVSENGETLVVTFKLKLSQLLDVHEKNQIMTTNVWLQHSWMDYKLRWDPVEYGGVEVLYVPSDTIWLPDVVLYN 117          

Query:  475 ILFFTTHGKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHAVDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKYXXXXXXXXXXXXXXXXXXXXXXXRSTMTHSMSPWIRYXXXXXXXXXXXXHSPISKEKEMSERCFMYCNKTMFKEASASKLIYETFMRRSKRSYSLKD 1374
            +L+    G+Y V  MTKA + + G V WTPPA+++SSC I+V +FP+D Q C M F SWTY+  ++ LKH +QK   D+    G       +DLR +Y SVE+DIL + A RH + +   +E +P++ FNI +RRKTLFYTVNLI+PC+ +S+LSVLVFYLP  SGEKI+L I+ILLS T+FFLL+ E IPSTSL +PL+GKYLLFT++L+ LS++IT+I+LN+++R   TH M PWIR  F+                K + +   M   K + ++ +A+K+ Y     ++K   +L D
Sbjct:  132 VLYNNADGEYVVTTMTKAILHYTGKVVWTPPAIFKSSCEIDVRYFPFDQQTCFMKFGSWTYDGDQIDLKHISQKNDKDNKVEIG-------IDLREYYPSVEWDILGVPAERHEKYYPCCAEPYPDIFFNITLRRKTLFYTVNLIIPCVGISYLSVLVFYLPADSGEKIALCISILLSQTMFFLLISEIIPSTSLALPLLGKYLLFTMLLVGLSVVITIIILNIHYRKPSTHKMRPWIRSFFI----------------KRLPKLLLMRVPKDLLRDLAANKINYGLKFSKTKFGQALMD 408          

Query:  141 RFNKPLEXXXXXXXXXQTSTGFKSAVQLYQKLLDENNYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLYN 491
            R  KPL +++++ +L +T      A +LY  LL  +NYN+LIRPV  N D V    GL+L+QLIDLN++DQ LTTNVW++ EWQD   +W+P +Y GV  L++PS  IWLPDIVLYN
Sbjct:   21 RHCKPLCLLLVLLLLCETVQANPDAKRLYDDLL--SNYNRLIRPVSNNTDTVLVKLGLRLSQLIDLNLKDQILTTNVWLEHEWQDHKFKWDPSEYGGVTELYVPSEHIWLPDIVLYN 135          

Query: 1363 SLKDASIEEK----INRTIADLKYVVDNLKDDDYKNKVQEEWRFVAVVMDRVFLLLFLSACVISTGSIILRSPALYDRRTPLD 1599
            SL D +  +K    + + I ++ ++  +++  D  N   ++W FVA+VMDR+FL LF+ A ++ T  I+  +P+LYD    +D
Sbjct:  476 SLSDVAARKKYPFELEKAIHNVMFIQHHMQRQDEFNAEDQDWGFVAMVMDRLFLWLFMIASLVGTFVILGEAPSLYDDTKAID 558          

Query:  475 ILFFTTHGKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHAVDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKYXXXXXXXXXXXXXXXXXXXXXXXRSTMTHSMSPWIR 1191
            +L+    G YEV +MTKA + H G V W PPA+Y+S C I+VE+FP+D Q C M F SWTY+ + + L+H  Q    DS N      I   +DL+++Y SVE+DI+ + A R+ + +    E + ++ FN+ +RRKTLFYTVNLI+PC+ +SFLSVLVFYLP+ SGEKISL I+ILLSLT+FFLLL E IP TSL +PL+GKYLLFT++L++LS+++T+ VLNVNFRS +TH M+PW++
Sbjct:  112 VLYNNADGNYEVTIMTKAILHHTGKVVWKPPAIYKSFCEIDVEYFPFDEQTCFMKFGSWTYDGYMVDLRHLKQTA--DSDN------IEVGIDLQDYYISVEWDIMRVPAVRNEKFYSCCEEPYLDIVFNLTLRRKTLFYTVNLIIPCVGISFLSVLVFYLPSDSGEKISLCISILLSLTVFFLLLAEIIPPTSLTVPLLGKYLLFTMMLVTLSVVVTIAVLNVNFRSPVTHRMAPWVQ 342          

Query:  213 AVQLYQKLLDENNYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLYN 491
            A +LY  LL  +NYN+LIRPV  N D +T   GL+L+QLID+N+++Q +TTNVWV+QEW D  L+WNP+DY GV  LH+PS  IWLPDIVLYN
Sbjct:   25 AKRLYDDLL--SNYNRLIRPVGNNSDRLTVKMGLRLSQLIDVNLKNQIMTTNVWVEQEWNDYKLKWNPDDYGGVDTLHVPSEHIWLPDIVLYN 115          

Query: 1390 KINRTIADLKYVVDNLKDDDYKNKVQEEWRFVAVVMDRVFLLLFLSACVISTGSIILRSPALYDRRTPLD 1599
            ++ +TI   +++  ++K+ D    V+E+W++VA+V+DR+FL +F  ACV+ T  IIL++P+LYD+  P+D
Sbjct:  476 EMEKTIEGSRFIAQHVKNKDKFESVEEDWKYVAMVLDRMFLWIFAIACVVGTALIILQAPSLYDQSQPID 545          

Query:  475 ILFFTTHGKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHAVDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKYXXXXXXXXXXXXXXXXXXXXXXXRSTMTHSMSPWIRYXXXXXXXXXXXXHSPISKEKEMSERCFMYCNKTMFKEA--------SASKLIYET--FMRRSKRSYSLKDASIEEKINRTIADLKYVVDNLKDDDYKNKVQEEWRFVAVVMDRVFLLLFLSACVISTGSIILRSPALYDRRTPL 1596
            +L+    G YEV LMTKA V   G V+W PPA+Y+S+C INVEFFP+D Q C M F SWTY+  ++ LKH  Q   PD  N      I + +DL+++  SVE+D+L + ARR  + +    E +P + FN+ +RRKTLFYTVNLI+PC+A+SFL+VL FYLP+ SGEKI+L I+ILLSLT+FFLLL + IP TS+V+PLIGKYLLFT+IL+S+SII+TV+VLNV+FRS  TH MSPW++ +FL+ LP +L +  P  + ++  +     CN    ++A         A+ + +E    + + +R+  L+       I + +  + ++ D+LK++D ++ V+E+WR+VA+V+DR+FL +F +AC++ T  IIL++P LYD R PL
Sbjct:  115 VLYNNADGNYEVTLMTKATVHPTGKVQWEPPAIYKSACPINVEFFPFDEQTCIMQFGSWTYDGFQVDLKHICQ---PDDYNDDYE--IGYGIDLKDYSRSVEWDLLSVPARRKAKYYTCCPEPYPFIIFNVTLRRKTLFYTVNLIIPCVAISFLTVLTFYLPSDSGEKITLCISILLSLTVFFLLLADLIPPTSIVVPLIGKYLLFTMILVSVSIIVTVVVLNVHFRSPSTHVMSPWVKKVFLQILPRLLMMRRPTPEGEKTPKVMVRACNGMEMRDAFGNSRQNCDANHMGHEEILLLGQEERNPGLRKRKYPVHIQKALEGVTFISDHLKNEDVEDMVKEDWRYVAMVLDRLFLWIFTTACLVGTLGIILQAPTLYDDRMPL 493          

Query:  189 QTSTGFKSAVQLYQKLLDENNYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLYN 491
            +   G   A +LY  LL ++ YNKLIRPV  N D +T   GL+LTQLID++ ++Q +TTNVW+  EW D  LRWNP+DY GV +L++P+++IWLPD+VLYN
Sbjct:   18 KVCEGTADAKRLYDDLLYKSGYNKLIRPVGNNSDKLTVKLGLRLTQLIDVDEKNQIMTTNVWLMHEWDDYKLRWNPKDYGGVNILYVPADRIWLPDVVLYN 118          

Query:  475 ILFFTTHGKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHAVDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKYXXXXXXXXXXXXXXXXXXXXXXXRSTMTHSMSPWIR-----YXXXXXXXXXXXXHSPISKEKEMSERCFMYCNKTMFKEASASKLI-----------YETFMRRSKRSYSLKDASIEEKINR--------TIADLKYVVDNLKDDDYKNKVQEEWRFVAVVMDRVFLLLFLSACVISTGSIILRSPALYDRRTPLD 1599
            +L+    G YEV LMTKA +  +G + W PPA+Y+SSC INVE+FP+D Q+C M F SWTY+  ++ L+H  Q        T+G+ +++  +DL+ FY SVE+DILE+ ARR+   +    E +P++TFN+ MRRKTLFYTVNLI+PC+ +SFL+VLVFYLP+ SGEK++L I+ILLSLT+FFLLL E IP TSL +PL+GKYLLFT++L++LSI++TV VLNV+FRS  TH MSPW++     ++           H   + E + S       N T +  A  +  +            E+ + +S+   S  D S +  +NR         +  ++++  ++KD+D  N+V E+W++VA+V+DR FL +F  AC++ T  I+ ++P+LYD RTP+D
Sbjct:  109 VLYNNADGNYEVTLMTKATLHSNGEIVWKPPAIYKSSCEINVEWFPFDEQSCAMKFGSWTYDGFQVDLQHMEQ--------TAGSNLVSIGIDLKEFYLSVEWDILEVPARRNEEYYPCCQEPYPDITFNLTMRRKTLFYTVNLIIPCVGISFLTVLVFYLPSDSGEKVTLCISILLSLTVFFLLLAEIIPPTSLAVPLLGKYLLFTMVLVTLSIMVTVGVLNVHFRSPSTHKMSPWVKKVFLEFMPRVLCMKRPEYHPRYAFESDFSTPANTATNGTDYGMAFGTGTLRRDSYYDSSPRTESSVDQSRHVKSFSDDSGDLGMNRQYSPEVLAALQSVQFIAQHIKDEDKDNEVIEDWKYVAMVLDRFFLWVFTLACILGTCGILFQAPSLYDTRTPID 499          

Query:  213 AVQLYQKLLDENNYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLYN 491
            A +LY  LL  +NYN+LIRPV  N + +T   GLKL+QLID+N++ Q +TTNVWV+Q+W D  L+W PE+Y GV+ L++PS  IWLPDIVLYN
Sbjct:   22 AKRLYDDLL--SNYNRLIRPVSNNSEKLTVKLGLKLSQLIDVNLKSQIMTTNVWVEQKWTDYKLQWIPEEYGGVEQLYVPSEHIWLPDIVLYN 112          

Query:  475 ILFFTTHGKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHAVDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKYXXXXXXXXXXXXXXXXXXXXXXXRSTMTHSMSPWIRYXXXXXXXXXXXXHSPISKEKEMSERCFMYCNKTMFKEASASKLIYET---FMRRSKRSYSLKDASIEEKIN-------------RTIADLKYVVDNLKDDDYKNKVQEEWRFVAVVMDRVFLLLFLSACVISTGSIILRSPALYDRRTPLD 1599
            +L+    G YEV LMTKA +  +G V W PPA+Y+SSC I+VEFFP+D+Q C M F SWTY+ +++ L HY       S N    V I   +D+R+FY SVE+D+L + A+R++R +    E +P++TF I MRRKTLFYTVNLI+PC+A+SFL+VLVFYLP+ SGEK++L I+ILLSLT+FFLLL E IP TS+V+PLIGKYLLFT+IL++LSII+TV+VLNV+FRS  TH MSPW+R +FL  LP +L +  P  + ++  +     CN    ++ S     + T     RRS     L  +S +   N               I  + ++ ++LK++D    + E+W++VA+V+DRVFL +F +ACV+ T  IIL++P LYD + P++
Sbjct:  116 VLYNNADGNYEVTLMTKATLHPNGLVVWEPPAIYKSSCTIDVEFFPFDVQTCSMKFGSWTYDGNQVDLVHYC------SINEESGVEIRPGIDIRDFYPSVEWDLLAVWAKRNVRNYPCCIELYPDITFYISMRRKTLFYTVNLIIPCVAISFLTVLVFYLPSDSGEKVTLCISILLSLTVFFLLLAEIIPPTSIVVPLIGKYLLFTMILVTLSIIVTVVVLNVHFRSPSTHVMSPWVRRVFLTILPKLLVMRRPHLEPEKPQKVVIRTCNGMEIRDHSGVSGYHHTTSMGFRRSMHEQELLPSSEDAAANALFRNKYYTREVIEAIESVTFIAEHLKNEDNTAAIIEDWKYVAMVLDRVFLWVFTTACVVGTFGIILQAPTLYDGKQPIN 500          

Query:  213 AVQLYQKLLDENNYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLYN 491
            A +LY  LL +  YNKLIRPV  N D +T   G++L+QLID++ +DQ +TTNVW++QEW D  L W+P +Y GV  L++PS +IWLPD+VLYN
Sbjct:   27 AKRLYDDLLRKRGYNKLIRPVGNNSDKLTVKLGIRLSQLIDVHEKDQIMTTNVWLRQEWYDKTLTWSPSEYGGVDKLYVPSREIWLPDVVLYN 119          

Query:  475 ILFFTTHGKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHAVDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKYXXXXXXXXXXXXXXXXXXXXXXXRSTMTHSMSPWIRYXXXXXXXXXXXXHSPISKEKEMSERCFMYCNKTMFKEASASKL--IYETFMR-RSKRSYSLKDASIEEKINRTIADLKYVVDNLKDDDYKNKVQEEWRFVAVVMDRVFLLLFLSACVISTGSIILRSPALYDRRTPLDGNHL 1611
            +L+    G YEV L+TKA V+  G V+W PPA+Y+S+C INVEFFP+D Q C M F SWTY+  ++ LKH  +        ++G     + +DL+++  SVE+D+L++ A+R  + +  + E  P +TFN+ +RRKTLFYTVNLI+PC+A+SFL+VL FYLP+ SGEKI+L I+ILLSLT+FFLLL + IP TSLV+PLIGKYLLFT+IL+SLSII+TV+VLNV+FRS  TH MSPW++ +FL+ LP +L +  P  + ++  +     CN    +E    +     E+ +R +  R+  LK+     ++ R +  + ++ D+LK +D ++ V+E+WR+VA+V+DR+FL +F +AC++ T  IIL++P LYD R PL  + L
Sbjct:  124 VLYNNADGNYEVTLLTKATVYPTGRVEWEPPAIYKSACPINVEFFPFDEQTCTMKFGSWTYDGLQVDLKHICELDGHREEFSTG-----YGIDLKDYSRSVEWDLLDVPAKRKAKYYNSKPEPHPFITFNVTLRRKTLFYTVNLIIPCVAISFLTVLTFYLPSDSGEKITLCISILLSLTVFFLLLADLIPPTSLVVPLIGKYLLFTMILVSLSIIVTVVVLNVHFRSPSTHVMSPWVKKVFLQILPRLLMMRRPTPEGEKTPKVMVRTCNGVEVREIFGDRRHSREESLLRGQDDRNSVLKNRKYSSEVRRALEGVAFISDHLKSEDLEDMVKEDWRYVAMVLDRLFLWIFTTACLVGTLGIILQAPTLYDDRMPLQTSKL 500          

Query:  189 QTSTGFKSAVQLYQKLLDENNYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLYN 491
            +   G   A +LY+ LL++  YNKLIRPV  N + +T   GL+LTQLID++ ++Q +TTNVW+  EW+D++LRW+P+DY  + +L++P+ ++W PD+VLYN
Sbjct:   27 RVCEGTVDAKRLYRDLLEKRGYNKLIRPVSDNNNNLTVKLGLRLTQLIDVDEKNQIMTTNVWLTHEWEDLSLRWDPKDYGNIDVLYVPAEQLWKPDVVLYN 127          

Query:  475 ILFFTTHGKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHAVDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKYXXXXXXXXXXXXXXXXXXXXXXXRSTMTHSMSPWIR----YXXXXXXXXXXXXHSPISKE-KEMSERCFM--------------------YCNKTMFKEASASKLIYETFMR--------------RSKRSYSLKDASIEEKINRTIADLKYVVDNLKDDDYKNKVQEEWRFVAVVMDRVFLLLFLSACVISTGSIILRSPALYDRRTPLD 1599
            +L+    G YEV LMTKA + + G V W PPA+Y+SSC I+VE+FP+D Q+C M F SWTY+  ++ LKH  QK         G+ ++   +DLR FY SVE+DILE+ ARR+        E +P++TFN+ MRRKTLFYTVNLI+PC+ +SFL+VLVFYLP+ SGEK      ++LSLT+FFLLL E IP TSL +PL+GKYLLFT+IL++LSI +TV VLNV+FRS  TH MSPW++    ++  + L      + P S+  K  SE+ +M                      +     E + S    E F+                S+R+YS        +I + I  ++++  ++KD D  N+V ++W++VA+V+DR+FL +F  ACV  T  II ++P+LYD R P+D
Sbjct:  117 VLYNNADGNYEVTLMTKATLKYTGEVVWRPPAIYKSSCEIDVEWFPFDEQSCNMKFGSWTYDGFQVDLKHTKQK--------RGSNIVEMGIDLREFYASVEWDILEVPARRNQEYIPDLPEPYPDITFNLTMRRKTLFYTVNLIIPCVGISFLTVLVFYLPSDSGEK------VILSLTVFFLLLAEIIPPTSLAVPLLGKYLLFTMILVTLSICVTVGVLNVHFRSPSTHKMSPWVKRVFIHVMPRLLLMRRPQYDPRSRHLKSPSEQEYMDGMADGDLSDPFGGEPYVEYNGDGGSLPEDAPSYKFNEDFLSSHATGKCDLGGCHLHSQRTYS-------PEIQKAIEGVQFIAQHIKDADRDNEVIQDWKYVAMVLDRLFLWVFTIACVAGTCGIIFQAPSLYDTRVPID 509          

Query:  213 AVQLYQKLLDENNYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLYN 491
            A +LY  LL  +NYN+LIRPV  N + +    GLKL+QLID+N+++Q +T+NVWV+QEW D  LRWNPEDY GV++L++PS  IWLPDIVLYN
Sbjct:   30 AKRLYDDLL--SNYNRLIRPVGNNSEKLIVKLGLKLSQLIDVNLKNQIMTSNVWVEQEWNDYKLRWNPEDYGGVEMLYVPSEHIWLPDIVLYN 120          

Query:  475 ILFFTTHGKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHAVDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKYXXXXXXXXXXXXXXXXXXXXXXXRSTMTHSMSPWIRYXXXXXXXXXXXXHSPISKEKEMSERCFMYCNKTMFKEASASKLIYETFMRRSKRSYSLKDASIEEKINRTIADLKYVVDNLKDDDYKNKVQEEWRFVAVVMDRVFLLLFLSACVISTGSIIL 1560
            +L+    G++ V  MTKA +F+ G V+W PPA+Y+SSC I+V FFP+D QNC+M F SWTY+  K+ L+                  +   VDL++++ S E+ I+      + +++    E +P++T+  I+RR  LFYT+NLI+PCL +S L+VLVFYLP+  GEKI+L I++LLSLT+F LL+ E IPSTSLVIPLIG+YLLFT+I ++LSIIITV VLNV+ RS  TH M  W+  +FL  +P  LF+  P    +       +         +  S        R ++     + + +   I + +  + Y+ D+L+ +D    V+E+W++VA+V+DR+FL +F+  C++ T  + L
Sbjct:  140 VLYNNADGEFAVTHMTKAHLFYTGKVRWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLER-----------------LETMVDLKDYWESGEWAIINAVGTYNTKKYDCCHEIYPDITYFFIIRRLPLFYTINLIIPCLLISCLTVLVFYLPSDCGEKITLCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMIFVTLSIIITVFVLNVHHRSPGTHEMPHWVHAVFLDLIPRWLFMRRPAPDSRRRQRLLLLQQGMACLPNSRHSGARINHTNRPTEED---QRSPLSPSIMQALEGVHYIADHLRAEDADFSVKEDWKYVAMVIDRIFLWMFIIVCLLGTIGLFL 481          

Query:  219 QLYQKLLDENNYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLYN 491
            +L++KL     YNK  RPV    D V   FGL + QLID++ ++Q +TTNVW++QEW D  LRW P DY+ V  + +PS  IW+PDIVLYN
Sbjct:   55 ELFKKLFI--GYNKWSRPVPNTSDVVIVKFGLSIAQLIDVDEKNQMMTTNVWLKQEWNDYKLRWKPSDYDNVTSIRVPSELIWVPDIVLYN 143          

Query:  475 ILFFTTHGKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHAVDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKYXXXXXXXXXXXXXXXXXXXXXXXRSTMTHSMSPWIRYXXXXXXXXXXXXHSPI------SKEKEMSERCFMYCNKTMFKEASASKLIYETFMRRSKRSYSLKDASIEEKINRTIADLKYVVDNLKDDDYKNKVQEEWRFVAVVMDRVFLLLFLSACVISTGSIILR 1563
            +L+    G + V+  TKA +  DGT+ W PPA+++SSC +++ +FP+D QNC M F SWTY+  K+ L                 V+I   V+L++F+ S E++I++    +H  ++    E +P++T++  +RR  LFYT+NLI+PCL +SFL+VLVFYLP+  GEK++L I++LLSLT+F L++ ETIPSTSLVIPLIG+YLLFT+I ++LSI+ITV VLNV++R+  TH+M  W+R +FL+ LP I+ +  PI      +K KE  E   + C K   ++ S   +        +  ++S+    +  +I + I  +KY+ +N++  +   +V+++W++VA+V+DR+FL +F+  CV+ T  +  +
Sbjct:  104 VLYNNAVGDFLVEDKTKALLKFDGTITWVPPAIFKSSCPMDITYFPFDYQNCSMKFGSWTYDKAKIDL-----------------VLIGSKVNLKDFWESGEWEIIDAPGYKHDIKYNCCEEIYPDITYSFYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHYRTPTTHTMPGWVRTVFLRALPRIMLMRRPIDQSESSTKAKEGPE---VDCGKVS-RQLSPQAI-------NTVVAFSV----VSPEIKQAIESVKYIAENMRSRNKAKEVEDDWKYVAMVIDRIFLWVFVLVCVLGTVGLFFQ 440          

Query:  252 YNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLYN 491
            YN+ IRPVE   D VT  F + ++QL+ ++  +Q + TN+W++  W D  L+W P +++G++ + +PSNKIW PDIVLYN
Sbjct:   28 YNQFIRPVENVSDPVTVEFEVSISQLVKVDEVNQIMETNLWLRHIWNDYKLKWIPAEFDGIEYIRVPSNKIWRPDIVLYN 107          

Query:  475 ILFFTTHGKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHAVDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKYXXXXXXXXXXXXXXXXXXXXXXXRSTMT-HSMSPWIRYXXXXXXXXXXXXHSPISKEKEMSERCFMYCNKTMFKEASASKLIYETFMRRSKRSYSLKDASIEEK-------INRTIADLKYVVDNLKDDDYKNKVQEEWRFVAVVMDRVFLLLFLSACVISTGSIILRSPAL 1575
            +L+    G++E  LMTKA V +DGT+ WTPPA Y+SSC ++V FFP+D QNC M F SWTY D  MV                   +++  VD ++F+ + E++IL+ + RR  R+    S  +P VT++ I++R  LFYT+ LI+PCL +SFL+VLVFYLP+  GEK+SLS ++L+SLT+F L++ E IPS+S VIPLIG+YLLF +I ++ SII+TV V+NV+ RS+ T H M+PW++ +FL+ LP +L +H               + ++  + +        +  M+R ++  +      EE+       + +  + ++Y+  ++K + +  +V ++W+FVA V+DR+FL  FL+  V+  G+I++ +PAL
Sbjct:  119 VLYENADGRFEGSLMTKAIVKYDGTITWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTY-DGTMV----------------DLALVDQHVDRKDFFDNGEWEILDATGRRGSRRDGIYS--YPFVTYSFILKRLPLFYTLFLIIPCLGLSFLTVLVFYLPSDEGEKLSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLLFIMIFVTFSIIVTVFVINVHHRSSATYHPMAPWVKSLFLQRLPRLLCMHG--------------HTDRYRYPDMELHSPELKRGMKRGQQRSACGVGVKEEENQAWMSMLEKATSSVRYISRHIKKEHFIREVVQDWKFVAQVLDRIFLWAFLTVSVL--GTILIFTPAL 458          

Query:  246 NNYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLY 488
              Y K +RPV    D +   FGLK++QL+D++ ++Q +TTNVW+ QEW D  LRW+PEDY G+  + +PS  IWLPDIVLY
Sbjct:   41 RGYQKWVRPVFHANDTIAVRFGLKISQLVDVDEKNQLMTTNVWLWQEWTDYKLRWDPEDYGGITSIRVPSENIWLPDIVLY 121          

Query:  475 ILFFTTHGKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHAVDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKYXXXXXXXXXXXXXXXXXXXXXXXRSTMT-HSMSPWIRYXXXXXXXXXXXXHSPISKEKEMSERCFMYCNKTMFKEASASKLIYETFMRRSKRSYSLKDASIEEK-------INRTIADLKYVVDNLKDDDYKNKVQEEWRFVAVVMDRVFLLLFLSACVISTGSIILRSPAL 1575
            +L+    G++E  LMTKA V +DGT+ WTPPA Y+SSC ++V FFP+D QNC M F SWTY D  MV                   +++  VD ++F+ + E++IL+ + RR  R+    S  +P VT++ I++R  LFYT+ LI+PCL +SFL+VLVFYLP+  GEK+SLS ++L+SLT+F L++ E IPS+S VIPLIG+YLLF +I ++ SII+TV V+NV+ RS+ T H M+PW++ +FL+ LP +L +H               + ++  + +        +  M+R ++  +      EE+       + +  + ++Y+  ++K + +  +V ++W+FVA V+DR+FL  FL+  V+  G+I++ +PAL
Sbjct:  105 VLYENADGRFEGSLMTKAIVKYDGTITWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTY-DGTMV----------------DLALVDQHVDRKDFFDNGEWEILDATGRRGSRRDGIYS--YPFVTYSFILKRLPLFYTLFLIIPCLGLSFLTVLVFYLPSDEGEKLSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLLFIMIFVTFSIIVTVFVINVHHRSSATYHPMAPWVKSLFLQRLPRLLCMHG--------------HTDRYRYPDMELHSPELKRGMKRGQQRSACGVGVKEEENQAWMSMLEKATSSVRYISRHIKKEHFIREVVQDWKFVAQVLDRIFLWAFLTVSVL--GTILIFTPAL 444          

Query:  246 NNYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLY 488
              Y K +RPV    D +   FGLK++QL+D++ ++Q +TTNVW+ QEW D  LRW+PEDY G+  + +PS  IWLPDIVLY
Sbjct:   27 RGYQKWVRPVFHANDTIAVRFGLKISQLVDVDEKNQLMTTNVWLWQEWTDYKLRWDPEDYGGITSIRVPSENIWLPDIVLY 107          

Query:  475 ILFFTTHGKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHAVDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKYXXXXXXXXXXXXXXXXXXXXXXXRSTMT-HSMSPWIRYXXXXXXXXXXXXHSPISKEKEMSERCFMYCNKTMFKEASASKLIYETFMRRSKRSYSLKDASIEEKINRTIADLKYVVDNLKDDDYKNKVQEEWRFVAVVMDRVFLLLFLSACVISTGSIILRSPAL 1575
            +L+    G++E  LMTKA + ++G V WTPPA Y+S+C ++V FFP+D QNC M F SWTY D  MV                  V++N+ VD R+F+ + E++IL  +  +  R  +  +  +P VT++ I++R  LFYT+ LI+PCL +SFL+VLVFYLP+  GEK+SLS ++L+SLT+F L++ E IPS+S VIPLIG+YLLF +I ++LSII+TV V+NV+ RS+ T H MSPW+R +FL+ LP +L +                + ++  + E        +  +R++      +  ++   + +    ++Y+  +++ + +  +V ++W+FVA V+DR+FL  FL+  V+  G+I++ +PAL
Sbjct:  121 VLYENADGRFEGSLMTKAIIKYNGAVTWTPPASYKSACTMDVTFFPFDRQNCSMKFGSWTY-DGTMV----------------DMVLMNYQVDRRDFFDNGEWEILSATGMKGNR--RDGTLSYPFVTYSFILKRLPLFYTLFLIIPCLGLSFLTVLVFYLPSDEGEKVSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLLFIMIFVTLSIIVTVFVINVHHRSSATYHPMSPWVRSLFLQRLPHLLCMRG--------------HTDRYHYPELEPQSPELKPRIRKAPPGPEGEGQALVNMLEKATCSVRYISRHIRKEHFIREVVQDWKFVAQVLDRIFLWAFLTVSVL--GTILIFTPAL 453          

Query:  249 NYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLY 488
             Y + +RP + + + V   FGLK++QL+D++ ++Q +TTNVW+ QEW D  LRWNPEDY G+  + +PS  IWLPDIVLY
Sbjct:   44 GYQRWVRPTQHSNNTVRVRFGLKISQLVDVDEKNQLMTTNVWLWQEWIDYKLRWNPEDYGGITFIRVPSESIWLPDIVLY 123          

Query:  475 ILFFTTHGKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHAVDLRNFYTSVEFDILELSARRHIRQFQGESEKF-PEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKYXXXXXXXXXXXXXXXXXXXXXXXRSTMT-HSMSPWIRYXXXXXXXXXXXXHS-------PISKEKEMSERCFMYCNKTMFKEASASKLIYETFMRRSKRSYSLKDASIEEKINRTIADLKYVVDNLKDDDYKNKVQEEWRFVAVVMDRVFLLLFLSACVISTGSIILRSPALYDRRT 1590
            +L+    G++E  ++TKA V HDG +KWTPPA+Y+SSC I+V FFP+D QNC M F SWTY+   + L                 +++N  VD   ++ + E++ L  +  + +R    +  +F P +T++ ++RR  LFYT+ LI+PCL +SFL+V VFYLP+  GEKISL  ++L+SLT+F L++ E IPS+S VIPLIG+YLLF +I ++LSIIITV V+NV+ RS+ T H M+PW+R +FL  LP IL + S       P   +++   R    C+      +++ +LI                          I  ++Y+  ++K ++   +V E+W+FVA V+DR+ L  FLS  V   GSI++  P +Y  R+
Sbjct:  122 VLYDNADGRFEGSIVTKAVVKHDGRIKWTPPAIYKSSCTIDVTFFPFDQQNCSMKFGSWTYDGTLVDL-----------------IMVNSDVDRGEYFDNGEWEFLNATGNKGVRL---DGHRFYPYITYSFVIRRLPLFYTLFLIVPCLGLSFLTVFVFYLPSDEGEKISLCTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLLFIMIFVTLSIIITVFVINVHHRSSSTHHPMAPWVRQLFLHKLPKILCMRSHVDRYTAPDEADRDHPGRAGCACHGGESPPSASERLILT-----------------------AIDSVRYITRHIKKENEVREVVEDWKFVAQVVDRILLWTFLSVSVF--GSILIFLPTIYAWRS 457          

Query:  210 SAVQLYQKLLDE--NNYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLYN 491
            S  +L  +LL     +Y K +RPV++  D V   FGL + QL+D++ ++Q +TTNVW++QEW D+NLRWNP+DY G+  + +P++ IWLPDIVLY+
Sbjct:   30 SLAELEDRLLKRMLKDYQKWVRPVDKLSDTVEVKFGLGIAQLVDVDEKNQLMTTNVWLKQEWVDINLRWNPDDYGGINSIRVPASSIWLPDIVLYD 125          

Query:  475 ILFFTTHGKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHAVDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKYXXXXXXXXXXXXXXXXXXXXXXXRSTMTHSMSPWIRYXXXXXXXXXXXXHSP------------ISKEKEMSERCF-------------MYCNKTMFKEASASKLIYETFMRRSKRSYSLKDASI-----------------------EEKINRTIADLKYVVDNLKDDDYKNKVQEEWRFVAVVMDRVFLLLFLSACVISTGSIILR 1563
            +L+    G ++V+  TKA + +DGTV W PPA+++SSC I+V +FP+D QNC M F SWTY+  K+ L                 V++   ++L++F+ S E+ I+++   +H  ++    + +P++T+++ +RR  LFYT+NLI+PCL +SFL+VLVFYLP+  GEK++LSI++LLSLT+F L++ ETIPSTSLVIPLIG+YLLFT+I ++LSI+IT+ VLNV++R+   H+M  W+R +FL  LP I+ L  P            +  E +    C                C       AS+S   + + +R  +    L+ A +                         +I + I  +KY+ +NL+  D   +V ++W++VA+V+DR+FL +F+  C++ T  + L+
Sbjct:   95 VLYNNADGDFQVEGKTKALLKYDGTVMWMPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWTYDKAKIDL-----------------VLVGTKINLKDFWESGEWVIIDVPGYKHDIKYNCCEQIYPDITYSVYVRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCGEKVTLSISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITIFVLNVHYRTPEAHTMPNWVRRVFLDTLPKIMLLQPPKGSVGTAASPDAVVSEADQQPACLCAGELSAAAASSSSSCQSGGISRASSSMEAHVSSVRLPR----LRAADVMSDELSSSSSTESLDALLALCLLSPEIRQVIDSVKYIAENLRTQDEAKEVCDDWKYVAMVVDRIFLWVFVLVCILGTAGLFLQ 484          

Query:  207 KSAVQLYQKLLDENNYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLYN 491
            ++A +LY+ L    +YN  IRPV    D V   F + ++QL+ L+  +Q + TN+W++  W D   +WNP  +EG++ + +PS+KIW PDIVLYN
Sbjct:    6 EAASRLYKTLF--TSYNPYIRPVFNVSDPVIVRFEVSMSQLVKLDEVNQIMATNLWLKHTWNDYKFQWNPGQFEGMEYIRVPSDKIWKPDIVLYN 98          

Query:  475 ILFFTTHGKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHAVDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKYXXXXXXXXXXXXXXXXXXXXXXXRSTMTHSMSPWIR 1191
            +L+    G + V  MTKA +FH G V+W PPA+Y+SSC I+V FFP+D QNC M F SWTY+  K+ L                 V +   VDL++++ S E+ I+      + +++    + +P++T++ I+RR  LFYT+NLI+PCL +S L+VLVFYLP+  GEKI+L I++LLSLT+F LL+ E IPSTSLVIPLIG+YLLFT+I ++LSI+ITV VLNV+ RS  TH+M  W+R
Sbjct:   61 VLYNNADGDFAVTHMTKAHLFHTGRVRWKPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDL-----------------VSMARDVDLKDYWESGEWAIVHAVGTYNTKKYDCCPQVYPDITYSFIIRRLPLFYTINLIIPCLLISCLTVLVFYLPSDCGEKITLCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPATHAMPRWVR 282          

Query:  321 TQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLYN 491
            T L D + ++Q +TTNVW++QEW D  L+W+P +YE V  + +PS  IW+PDIVLYN
Sbjct:    8 THLCDCDEKNQMMTTNVWLKQEWDDYKLQWDPAEYENVTSIRVPSELIWVPDIVLYN 64          

Query: 1405 IADLKYVVDNLKDDDYKNKVQEEWRFVAVVMDRVFLLLFLSACVISTGSIIL 1560
            +  ++Y+ ++L+ +D    V+E+W++VA+V+DR+FL +F+  C++ T  + L
Sbjct:  507 VQGVQYIANHLRAEDAHLSVKEDWKYVAMVIDRIFLWVFIVVCLLGTVGLFL 558          

Query:  496 GKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINH-AVDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKYXXXXXXXXXXXXXXXXXXXXXXXRSTMTHSMSPWIRYXXXXXXXXXXXXHSPISKEKEMSERCFM------YCNKTMFKEASASK--LIYETFMRRSKRSYSLKDAS-------IEEKINRTIADLKYVVDNLKDDDYKNKVQEEWRFVAVVMDRVFLLLFLSACVISTGSIILRS 1566
            G ++  L     V + G V+W PP++YRSSC + V++FP+D QNC M F S+TY+  ++ L++   +   +         I H  +D   F  S E+ I    +R++          + ++TF +IM RK LFY +N+++PC+ ++  +V  FYLP  +GEK+ L I++LL+LT+F LLL + +P TSL +P+I  YL+FT+++++  +I+TVIVLN++FRS  TH M  W+R IF+  LP  L++  P  K++E++ +  +      +C+   F     S+  L+  T        +S + A        +  ++   +  + Y+ +++      ++++E+W++VA+V+DR+F + F     + T  I   +
Sbjct:  120 GNFDFGLYVHVLVDYTGAVRWVPPSIYRSSCGMQVKYFPFDWQNCSMVFQSFTYDTSEINLEYALDEHRQE---------IRHIIIDESTFPVSGEWQIKHKPSRKNT---NPRDPLYQDITFYLIMERKPLFYIINIVVPCILITICAVFTFYLPPDAGEKMGLCISVLLALTVFLLLLADKVPETSLGVPVIVNYLMFTMVIVTACVILTVIVLNLHFRSPATHIMPYWVRRIFIHSLPKYLWIERP--KKEELAPKLPVLTQHQQHCHDEYFIRTPPSQALLLLPTSPSFGMTPFSSELAGPDKLHVVLPPELQSAVDAVHYISEHMLSQKEFDELKEDWQYVAMVVDRIFFITFFLITSLGTFGIFFNA 478          

Query:  201 GFKSAVQLYQKLLDENNYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLYN 491
            G ++   L + L     Y  L+RP       VT   G+ L+QLI L      +T +  +   W+D  L W+P +Y+ ++ + +   ++WLPDI L N
Sbjct:   20 GLEAEENLLKDLFVVQQYKTLVRPARTATGRVTVRLGMTLSQLISLPACQPDMTLSRLISLSWEDPRLSWDPRNYDNLRSIRLSPKRVWLPDIALSN 116          

Query:  475 ILFFTTHGKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHAVDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKY 1083
            +L+ +   +++    T   V + G  +  PP + +S+C+I+V +FP+D+Q C + F SWT++   + L+          ++TSG            +  + E+D++E+  +R+   +    E +P+VT+ + +RR+TL+Y +NL++PC+ +S LS+LVF LP  SGEKISL I +LLSLT+F LL+ E +P+TS  +PLIG+Y
Sbjct:   22 LLYNSADERFDATFHTNVLVNYTGNCQHLPPGMLKSTCYIDVRWFPFDVQKCDLKFGSWTHDGWLIDLQML-------EADTSG------------YIANGEWDLVEIPGKRNELYYDCCQEPYPDVTYTLTIRRRTLYYGLNLLVPCVLISALSLLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIGQY 205          

Query: 1375 ASIEEKINRTIADLKYVVDNLKDDDYKNKVQEEWRFVAVVMDRVFLLLFLSACVISTGSIILRSP 1569
            A +  +I + + +L+Y+    +  D    +  EW+F A V+DR+ LL F    +IST SI++ +P
Sbjct:  348 AGMSSEITKILIELRYIAGRFRTQDENEAIASEWKFAAAVVDRLCLLAFTLFTIISTISILMSAP 412          

Query:  496 GKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHAVDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKY 1083
            G    K+ T   V HDG+  W  PA+ +S C I+V FFP+D+Q+C++TF SWT++  K+ +    + GI                D  NF  + E+ +   S RR ++ +    E +P VT+ II+RR+ +FY  N+++P   ++ LS+  FYLP  SGE++S  I +LL+++++ +++ E IP ++  IPL+ K+
Sbjct:   98 GSLNNKIDTNVIVNHDGSTTWLAPAIIKSECKIDVRFFPFDVQSCELTFGSWTHDGLKIDIHLKQESGI----------------DTENFSDNREWFLKGTSGRRDVKMYICCPEPYPTVTYTIILRRRAMFYVFNMVLPTGVIALLSLFSFYLPPNSGERVSFVITVLLAMSVYLIMVTENIPRST-DIPLVSKF 276          

Query:  249 NYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLYN 491
            NY+K  RPV    D V    G+ L Q+IDLN RDQ LT NVW++Q W+D  L+WNP+D+ G++ ++I  +++W PD++LYN
Sbjct:   11 NYSKDARPVLNVNDPVQLKLGIMLRQVIDLNERDQILTINVWIRQYWKDHLLKWNPDDFGGIKSINIAPDRVWKPDVLLYN 91          

Query:  487 TTHGKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHAVDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKYXXXXXXXXXXXXXXXXXXXXXXXRSTMTHSMSPWIRYXXXXXXXXXXXXHSPISKEKEMSERCFMYCNKTMFKEASASKLIYETFMRRSKRSYSLKDASIEEKINRTIADLKYVVDNLKDDDYKNKVQEEWRFVAVVMDRVFLLLFLSACVISTGSIILRSPAL 1575
            T  G  E K  T      DGT +W  PA + S+C+INV +FP+D QNC + F SWTY  +++     T     DS+            DL  +  + E+ +L + A+ +   +      F +VT  + ++RK L+Y  NLI+PC  ++ L+++ F+LP +SGEK+ L I +LL++T+F LL+ ET+PSTS  IPL+G+Y + T+ + ++S++ T ++LN   R+  T  M  W++      +       SP +      +       ++   E               +R  S   + +     R + D+  + ++++      +++EEWR  A+V+DR+F  + L   ++++  I  R P +
Sbjct:  133 TYAGGLE-KYKTSVIASSDGTQEWNSPASFTSTCNINVRYFPFDSQNCSLKFGSWTYVGNRL-----TMTSTSDSA------------DLSKYVNNGEWHLLAMPAKLNRVFYNCCKYPFYDVTLYLEIQRKPLYYVFNLIIPCALIATLTLIKFFLPPESGEKVGLGITVLLAMTVFLLLVAETLPSTSDHIPLLGQYFVATMFVTAISLVATCLILNFFHRNPSTSPMPHWVK-----VIILDYMARSPRNARLMRDDSVIPPSGRSTPCE---------------RRRMSTVSSQLNPFTERLLDDINVLAEDVRARQEDERLREEWRCAALVLDRMFFWIMLVTSLMTSFMIFYRDPVM 457          

Query:  249 NYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLYN 491
            NY+  +RPV  + D V   F L L Q+I +N + Q +T +VW++Q+W +  L WN   Y G++ +++   K+W+PDI+LYN
Sbjct:   48 NYDSEVRPVFNDSDKVNVEFSLSLIQIIAVNSKSQLVTVSVWIRQKWTNPMLAWNTSKYGGIESVNLNPAKVWIPDIILYN 128          

Query:  511 KLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHAVDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKY 1083
            K  T+A + H+G  +W  P    S C I++ +FP+D Q C+M F SW+Y+  ++ L   T KG  DS+            DL  +  S E+D+L + A R++ ++    + F ++TF + +RRK LFY  NLI PC+ ++ L+V  F LP +SGE+I L I I L LT+F L+  E +P TS VIPLIGKY
Sbjct:  129 KFDTRATIMHNGYTEWFAPTEIHSICAIDITYFPFDEQFCKMKFGSWSYSGRQLNL---TSKG--DSA------------DLSKYTKSGEWDLLGMRAVRNVVKYSCCPDPFIDITFTMHIRRKVLFYLTNLIAPCIVLATLTVFSFQLPLESGERIGLVITIWLGLTVFMLVFTENVPRTSEVIPLIGKY 302          

Query:  228 QKLLDE--NNYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLYN 491
             +LL++   +YNK  RPV    +A+   F +   QLI+LN +DQ L + VW +Q W +  L W+P+ Y G+  +++  N IW PDIVLY+
Sbjct:   28 HRLLNDLFKDYNKEARPVLNKSEAIEVQFDMAYAQLINLNSKDQILQSKVWFRQRWVNPFLTWDPKMYGGLTSINVNPNMIWKPDIVLYH 117          

Query:  520 TKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHAVDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKY 1083
            TK  +  DGT  W  P++ RS C I++ FFP+D Q C + F SWTY+  ++           D +N S       +VDL ++  S EF+++     R I ++    E +P + F + +RRK LFY  NLI+PC  ++  ++L F LP  +GE+++L I  LL++T+F L++ E  P+TS V PLIGK+
Sbjct:  109 TKVILSSDGTNTWYAPSILRSRCSIDITFFPFDDQRCTLHFGSWTYDGLRV-----------DLTNMSA------SVDLSSYMPSGEFEMINAPVDRIIVRYSCCPEPYPNLVFTLHIRRKVLFYFNNLIVPCFLITAFALLTFVLPPNTGERVTLVITTLLAMTVFMLMIAENTPTTSDVTPLIGKF 279          

Query:  249 NYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQE---------WQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLYN 491
            N ++ +RPV+  E A+  +FG+  TQL++L+ ++Q L +NVW++Q          W +  LRWN   Y G++ ++I    +WLPDIVLYN
Sbjct:   11 NSSQEVRPVKNKESAIKVFFGIAYTQLVELDAKNQVLVSNVWIRQASNCIGLKCLWNNHLLRWNESHYGGIKSINIDPKLVWLPDIVLYN 100          

Query:  511 KLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHAVDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKY 1083
            K  T+ K+  +G   W  P +  SSC I+V +FP+D Q+C + F SWTY+  ++ L   +  G                 D+  +  S ++D++  +A+R+   +    + +P+VTF + +RRKT+FY +NLIMPC  ++ L++L F+LP +SGE+I+L I  LL++T+F LL+ + +P TS V+PLI  Y
Sbjct:  103 KFGTQIKLLFNGINIWLAPVLLTSSCKIDVTYFPFDEQHCSLKFGSWTYDGERLDLVSESPSG-----------------DVSKYVPSGQWDLVSFTAKRNEIFYVCCPQSYPDVTFTLNIRRKTIFYYMNLIMPCFLITGLTLLSFFLPPESGERITLVITNLLAMTVFMLLVADWLPPTSEVVPLISMY 276          

Query:  249 NYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLYN 491
            NYNK +RPV     A+T   GL L Q+  L  + Q L T++WV+Q W++  L W+P+++ G+  +++  +K+W+PDI LYN
Sbjct:   11 NYNKHLRPVVNKSRALTVRLGLTLHQIASLVEKSQFLQTSLWVRQMWRNEYLTWDPKEFGGISTINVNVDKVWVPDIYLYN 91          

Query:  475 ILFFTTHGKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHAVDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKYXXXXXXXXXXXXXXXXXXXXXXXRSTMTHSMSPWIRYXXXXXXXXXXXXHSPISKEKEM---SERCFMY--CNKTMFKEASASKLIYETFMRR----SKRSYSLKDASIEEKINRTIA-------------DLKYVVDNLKDDDYKNKVQEEWRFVAVVMDRVFLLLFLSACVISTGSIILR 1563
            +L+    G + V+  TKA +  DGT+ W PPA+++SSC +++ +FP+D QNC M F SWTY+  K+ L                 V+I   V+L++F+ S E++I++    +H  ++    E +P++T++  +RR  LFYT+NLI+PCL +SFL+VLVFYLP+  GEK++L I++LLSLT+F L++ ETIPSTSLVIPLIG+YLLFT+I ++LSI+ITV VLNV++R+ MTH+M  W+  +FLK LP I+ +  P  ++ ++   S  C  Y  C  +      A K        R    +  S  +K    ++ IN  +A              +KY+ +N++  +   +V+++W++VA+V+DR+FL +F++ C++ T  + L+
Sbjct:  116 VLYNNAVGDFLVEDKTKALLKFDGTITWVPPAIFKSSCPMDITYFPFDYQNCSMKFGSWTYDKAKIDL-----------------VLIGSKVNLKDFWESGEWEIIDAPGYKHDIKYNCCEEIYPDITYSFYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHYRTPMTHTMPGWVHLVFLKVLPRIMLMRRPTDEDGKVGGGSLNCLEYGDCKLSSMDGCGAKKCPCPCQHGRETPETAASVRMKHQLSQQSINTVVAFSVVSPEVKQAIESVKYIAENMRSRNKAKEVEDDWKYVAMVIDRIFLWVFVTVCLLGTMGLFLQ 483          

Query:  207 KSAVQLYQKLLDENNYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLYN 491
            K+  +L++KL     YN+ IRPVE   D VT  F + ++QL+ ++  +Q + TN+W++  W D  LRW P +++G++ + +PSNKIW PDIVLYN
Sbjct:   27 KAEDRLFRKLF--RRYNQFIRPVENVSDPVTVEFEVSISQLVKVDEVNQIMETNLWLRHIWNDYKLRWTPAEFDGIEFIRVPSNKIWRPDIVLYN 119          

Query:  475 ILFFTTHGKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHAVDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKYXXXXXXXXXXXXXXXXXXXXXXXRSTMT-HSMSPWIR--YXXXXXXXXXXXXHSPISKEKEMSERCFMYCNKTMFKEASASKLIYETFMRRSKRSYSLKDASIEEKINRTIADLKYVVDNLKDDDYKNKVQEEWRFVAVVMDRVFLLLFLSACVISTGSIILRSPAL 1575
            +L+    G++E  LMTKA V  DGT+ WTPPA Y+SSC ++V FFP+D QNC M F SWTY+                  N    V+++H VD ++F+ + E++IL  + +R  R  + E   +P +T++ I++R  LFYT+ LI+PCL +SFL+VLVFYLP+  GEK+SLS ++L+SLT+F L++ E IPS+S VIPLIG+YLLF +I ++ SII+TV V+NV+ RS+ T H M+PW++  ++        +  H+      ++  R      +   +  +  + +     + +         +    + +    + Y+  +++ + +  +V ++W+FVA V+DR+FL  FL+  ++  G++++ +PAL
Sbjct:  121 VLYENADGRFEGSLMTKAIVRWDGTITWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYD-----------------GNMVDLVLVDHYVDRKDFFDNGEWEILNATGQRGSR--RDEMYWYPFLTYSFILKRLPLFYTLFLIIPCLGLSFLTVLVFYLPSDEGEKLSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLLFIMIFVTFSIIVTVFVINVHHRSSATYHPMAPWVKSLFLQKLPRLLCMRGHTDRYHFPDIEMR----SPELKTRRGAGRRAVPGGQQKGALGGMEDDSQAWLAMLEKATNSVHYISRHIRKEHFIREVVQDWKFVAQVLDRIFLWAFLTVSIL--GTVLIFTPAL 465          

Query:  246 NNYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLY 488
              Y K +RPV+   D +T  FGLK++QL+D++ ++Q +TTNVW+ QEW DV L+WNP+DY G+  + +PS  IWLPDIVLY
Sbjct:   43 KGYQKWVRPVQHANDTITVRFGLKISQLVDVDEKNQLMTTNVWLWQEWIDVKLKWNPDDYGGITSIRVPSETIWLPDIVLY 123          

Query:  475 ILFFTTHGKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHAVDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKYXXXXXXXXXXXXXXXXXXXXXXXRSTMTHSMSPWIRYXXXXXXXXXXXXHSPISKEKEMSERC--FMYCNKTM 1296
            +L+    G + V  +TKA +F+DG +KW PPA+Y+SSC I+V FFP+D Q+C+M F SWTY+  K+ L                 + +   VD  +++ S E+ I+    + + ++++  +E + ++T+  I+RR  LFYT+NLI+PCL +S L+VLVFYLP+Q GEKI+L I++LLSLT+F LL+ E IPSTSLVIPLIG+YLLFT++ ++LSIIIT+ VLNV+ RS  TH M  W+R +FL  +P +LF+  P    K+  +R    M+C  T+
Sbjct:  132 VLYNNADGDFAVTHLTKAHLFYDGQIKWMPPAIYKSSCSIDVTFFPFDQQSCKMKFGSWTYDRAKIDL-----------------ISMASDVDQMDYWESGEWVIVNAVGKYNTKKYECCAEIYADITYYFIIRRLPLFYTINLIIPCLLISCLTVLVFYLPSQCGEKITLCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMVFVTLSIIITIFVLNVHHRSPQTHGMPHWVRRVFLDLVPRVLFMKRPPGTAKQHCKRLIEMMHCPTTI 390          

Query:  252 YNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLYN 491
            YNKL RPV+   D V  +FGL + QLID++ ++Q +TTNVW++QEW D  LRWNPEDYE V  + IPS  IW PDIVLYN
Sbjct:   56 YNKLSRPVQNTSDTVLVHFGLSIAQLIDVDEKNQMMTTNVWLKQEWNDYKLRWNPEDYENVTSIRIPSEIIWRPDIVLYN 135          

Query: 1381 IEEKINRTIADLKYVVDNLKDDDYKNKVQEEWRFVAVVMDRVFLLLFLSACVISTGSIIL 1560
            +   + R I  ++Y+ D+L+  D    V+E+W++VA+V+DR+FL +F+  C++ +  + L
Sbjct:  579 VSPAMQRAIEGVQYIADHLRAGDADFSVKEDWKYVAMVIDRIFLWMFVLVCILGSVGLFL 638          

Query:  475 ILFFTTHGKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHAVDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKYXXXXXXXXXXXXXXXXXXXXXXXRSTMTHSMSPWI 1188
            +L+    G++ V  MTKA +FH G V+W PPA+Y+SSC I+V FFP+D QNC+M F SWTY+  K+ L+                  I + VDL N++ S E+ I+      + +++    E +P++T+  I+RR  LFYT+NLI+PCL +S L+VLVFYLP+  GEKI+L I++LLSLT+F LL+ E IPSTSLVIPLIG+YLLFT+I ++LSI+ITV VLNV+ RS  TH M  W+
Sbjct:  131 VLYNNADGEFAVTHMTKAHLFHTGKVRWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLER-----------------IENTVDLNNYWESGEWAIINAVGTYNTKKYDCCHEIYPDITYFFIIRRLPLFYTINLIIPCLLISCLTVLVFYLPSDCGEKITLCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPSTHKMPRWV 351          

Query:  219 QLYQKLLDENNYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLYN 491
            +L+Q L     YNK  RPV    D V   FGL + QLID++ ++Q +TTNVW++QEW D  LRW P DY+ V  + +PS  IW+PDIVLYN
Sbjct:   46 ELFQTLF--TGYNKWSRPVPNISDVVIVKFGLSIAQLIDVDEKNQMMTTNVWLKQEWNDYKLRWKPSDYDNVTSIRVPSELIWVPDIVLYN 134          

Query:  475 ILFFTTHGKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHAVDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKYXXXXXXXXXXXXXXXXXXXXXXXRSTMTHSMSPWI 1188
            +L+    G++ V  MTKA +FH G V+W PPA+Y+SSC I+V FFP+D QNC+M F SWTY+  K+ L+                  I + VDL N++ S E+ I+      + +++    E +P++T+  I+RR  LFYT+NLI+PCL +S L+VLVFYLP+  GEKI+L I++LLSLT+F LL+ E IPSTSLVIPLIG+YLLFT+I ++LSI+ITV VLNV+ RS  TH M  W+
Sbjct:  131 VLYNNADGEFAVTHMTKAHLFHTGKVRWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLER-----------------IENTVDLNNYWESGEWAIINAVGTYNTKKYDCCHEIYPDITYFFIIRRLPLFYTINLIIPCLLISCLTVLVFYLPSDCGEKITLCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPSTHKMPRWV 351          

Query:  219 QLYQKLLDENNYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLYN 491
            +L+Q L     YNK  RPV    D V   FGL + QLID++ ++Q +TTNVW++QEW D  LRW P DY+ V  + +PS  IW+PDIVLYN
Sbjct:   46 ELFQTLF--TGYNKWSRPVPNISDVVIVKFGLSIAQLIDVDEKNQMMTTNVWLKQEWNDYKLRWKPSDYDNVTSIRVPSELIWVPDIVLYN 134          

Query:  475 ILFFTTHGKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHAVDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKYXXXXXXXXXXXXXXXXXXXXXXXRSTMTHSMSPWIRYXXXXXXXXXXXXHSPISKEKEMSERCFMYCNKTMFKEASASKLIYETFMRRSKRSYSLKDASIEEKINRTIADLKYVVDNLKDDDYKNKVQEEWRFVAVVMDRVFLLLFLSACVISTGSIILRSPALYDRRTPLDGNHLPNQTLLTYSTPNGNYSLDVNLN 1677
            ILFFTTHGKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHAVDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEK               + L+ETIPSTSLVIPLIGKYLLFTIILISLSIIITVIVLNVNFRSTMTHSMSPWIRYIFLKFLPPILFLHSPISKEKEMSERCFMYCNKTMFKEAS SKLIYETFMRRSKRSYSLKDASIEEKINRTIADLKYVVDNLKDDDYKNKVQEEWRFVAVVMDRVFLLLFLSACVISTGSIILRSPALYDRRTPLDGNHLPNQTLLTYSTPNGNYSLDVNLN
Sbjct:  101 ILFFTTHGKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHAVDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEK---------------ISLIETIPSTSLVIPLIGKYLLFTIILISLSIIITVIVLNVNFRSTMTHSMSPWIRYIFLKFLPPILFLHSPISKEKEMSERCFMYCNKTMFKEASVSKLIYETFMRRSKRSYSLKDASIEEKINRTIADLKYVVDNLKDDDYKNKVQEEWRFVAVVMDRVFLLLFLSACVISTGSIILRSPALYDRRTPLDGNHLPNQTLLTYSTPNGNYSLDVNLN 486          

Query:  132 MWPRFNKPLEXXXXXXXXXQTSTGFKSAVQLYQKLLDENNYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGV 434
            MWPRFNKPLEIIIIIYILIQTSTGFKSAVQLYQKLLDENNYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEG+
Sbjct:    1 MWPRFNKPLEIIIIIYILIQTSTGFKSAVQLYQKLLDENNYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGI 101          

Query:  475 ILFFTTHGKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHAVDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKYXXXXXXXXXXXXXXXXXXXXXXXRSTMTHSMSPWIRYXXXXXXXXXXXXHSPISKEKEMSERCFMYCNKTMFKEASASKLIYETFMRRSKRSYSLKDASIEEKINRTIADLKYVVDNLKDDDYKNKVQEEWRFVAVVMDRVFLLLFLSACVISTGSIILRSPALYDRRTPLDGNHLPNQTLLTYSTPNGNYSLDVNLN 1677
            +L+ T  GKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHAVDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEK               + L+ETIPSTSLVIPLIGKYLLFTIILISLSIIITVIVLNVNFRSTMTHSMSPWIRYIFLKFLPPILFLHSPISKEKEMSERCFMYCNKTMFKEAS SKLIYETFMRRSKRSYSLKDASIEEKINRTIADLKYVVDNLKDDDYKNKVQEEWRFVAVVMDRVFLLLFLSACVISTGSIILRSPALYDRRTPLDGNHLPNQTLLTYSTPNGNYSLDVNLN
Sbjct:  117 VLYNTADGKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHAVDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEK---------------ISLIETIPSTSLVIPLIGKYLLFTIILISLSIIITVIVLNVNFRSTMTHSMSPWIRYIFLKFLPPILFLHSPISKEKEMSERCFMYCNKTMFKEASVSKLIYETFMRRSKRSYSLKDASIEEKINRTIADLKYVVDNLKDDDYKNKVQEEWRFVAVVMDRVFLLLFLSACVISTGSIILRSPALYDRRTPLDGNHLPNQTLLTYSTPNGNYSLDVNLN 502          

Query:  132 MWPRFNKPLEXXXXXXXXXQTSTGFKSAVQLYQKLLDENNYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLYNTW*I*S*ADDKSE 530
            MWPRFNKPLEIIIIIYILIQTSTGFKSAVQLYQKLLDENNYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLYNT      AD K E
Sbjct:    1 MWPRFNKPLEIIIIIYILIQTSTGFKSAVQLYQKLLDENNYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLYNT------ADGKYE 127          

Query:  475 ILFFTTHGKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHAVDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKYXXXXXXXXXXXXXXXXXXXXXXXRSTMTHSMSPWIR 1191
            +LF    GKYE+ + TKA VFHDGTVKW PPA+Y+SSC INVEFFPYDIQ C +TFASWTY   K+ LKH  QK + D  N +G V I+ AVDL NFY SVEFDILELSA R +  +   S   P+VTF I+MRRKTLFYTVNL+MPCLA+ FLSVL FYLP++SGEK+ LSI IL SLTLFFLLLVETIPSTSLVIPLIGKYLLFT+ILISLSII+TV +LNV+FRS+++H M  W++
Sbjct:  161 VLFNNIDGKYEISIKTKATVFHDGTVKWIPPAIYKSSCQINVEFFPYDIQECFLTFASWTYEGSKVNLKHMAQKNVIDIPNATGMVNIDFAVDLTNFYESVEFDILELSAERSLVTYLQPS---PKVTFKILMRRKTLFYTVNLMMPCLAICFLSVLAFYLPSESGEKVYLSITILFSLTLFFLLLVETIPSTSLVIPLIGKYLLFTMILISLSIILTVYILNVHFRSSLSHDMPDWVK 396          

Query:  201 GFKSAVQLYQKLLDENNYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLYN 491
             +K A++LY+ L+D +NY+  IRPV  N D +T Y GL+L+QL ++NMR + +TTNVW++Q+W DVNLRWNP  Y GV  L+IPS+KIWLPDIVL+N
Sbjct:   68 AYKDAIRLYKVLMDGSNYSNYIRPVNYNNDVLTVYLGLRLSQLSEVNMRKETVTTNVWLEQQWIDVNLRWNPNQYGGVTKLYIPSDKIWLPDIVLFN 164          

Query: 1381 IEEKINRTIADLKYVVDNLKDDDYKNKVQEEWRFVAVVMDRVFLLLFLSACVISTGSIILRSPALYDRRTPLDGNHLPNQTLLTYSTPNGNYSLDVN 1671
            ++ KI+R I ++++V + L+ DD  N ++E+W+FVA+VMDR+FL  F SAC++ST  IIL+SPALYD R P+  N++PN T L Y   +G +++ +N
Sbjct:  503 LDWKIDRAIDEVQFVANQLRADDESNDIKEDWKFVAMVMDRLFLWTFSSACLMSTLGIILQSPALYDTRKPIHSNNVPNCTNLFYQLRSGVHNVKIN 599          

Query:  475 ILFFTTHGKYEVKLMTKAKVFHDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHAVDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKYXXXXXXXXXXXXXXXXXXXXXXXRSTMTHSMSPWIR 1191
            +LF    GKYE+ + TKA VFHDGTVKW PPA+Y+SSC INVEFFPYDIQ C +TFASWTY   K+ LKH  QK + D  N +G V I+ AVDL NFY SVEFDILELSA R +  +   S   P+VTF I+MRRKTLFYTVNL+MPCLA+ FLSVL FYLP++SGEK+ LSI IL SLTLFFLLLVETIPSTSLVIPLIGKYLLFT+ILISLSII+TV +LNV+FRS+++H M  W++
Sbjct:  113 VLFNNIDGKYEISIKTKATVFHDGTVKWIPPAIYKSSCQINVEFFPYDIQECFLTFASWTYEGSKVNLKHMAQKNVIDIPNATGMVNIDFAVDLTNFYESVEFDILELSAERSLVTYLQPS---PKVTFKILMRRKTLFYTVNLMMPCLAICFLSVLAFYLPSESGEKVYLSITILFSLTLFFLLLVETIPSTSLVIPLIGKYLLFTMILISLSIILTVYILNVHFRSSLSHDMPDWVK 348          

Query:  201 GFKSAVQLYQKLLDENNYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLYN 491
             +K A++LY+ L+D +NY+  IRPV  N D +T Y GL+L+QL ++NMR + +TTNVW++Q+W DVNLRWNP  Y GV  L+IPS+KIWLPDIVL+N
Sbjct:   20 AYKDAIRLYKVLMDGSNYSNYIRPVNYNNDVLTVYLGLRLSQLSEVNMRKETVTTNVWLEQQWIDVNLRWNPNQYGGVTKLYIPSDKIWLPDIVLFN 116          

Query: 1381 IEEKINRTIADLKYVVDNLKDDDYKNKVQEEWRFVAVVMDRVFLLLFLSACVISTGSIILRSPALYDRRTPLDGNHLPNQTLLTYSTPNGNYSLDVN 1671
            ++ KI+R I ++++V + L+ DD  N ++E+W+FVA+VMDR+FL  F SAC++ST  IIL+SPALYD R P+  N++PN T L Y   +G +++ +N
Sbjct:  455 LDWKIDRAIDEVQFVANQLRADDESNDIKEDWKFVAMVMDRLFLWTFSSACLMSTLGIILQSPALYDTRKPIHSNNVPNCTNLFYQLRSGVHNVKIN 551          

Query:  475 ILFFTTHGKYEVKLMTKAKVF--HDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHAVDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEKXXXXXXXXXXXXXXXXXXVETIPSTSLVIPLIGKYXXXXXXXXXXXXXXXXXXXXXXXRSTMTHSMSPWIRYXXXXXXXXXXXXHSPISKEKEMSERCFMYCNKT-----MFKEASASKLIYETFMRRSKRSYSLKDASIEEKINRTIADLKYVVDNLKDDDYKNKVQEEWRFVAVVMDRVFLLLFLSACVISTGSIILR 1563
            +L+    G +++   +  KV   HDG+V W PP +++S C INVEFFP+D Q C +   +WT+N   + L+H  QK    +S  +    I++A+DL  +  +VE+D+LE+SA+R+I  +   +E + +++FN+ +RR+TLFY +NLI PCLA+SFL++LVFYLP  SGEK+SLSI+ILLSLT+FFLL+ +  P TS+V+PLI KYLLFT+IL++LS++ TV+VLN+++RS  TH M+PW+R +F   LP +LF+  P    ++         N+T      F E      I + +   S R  ++   ++  +I   +  ++ +V ++K ++  + ++++W++VAVV+DR+FL LF  A +I     + R
Sbjct:  109 VLYNNAGGDWDLASSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTEPYLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKVSLSISILLSLTVFFLLIFDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDTHKMAPWVRSVFTSTLPKLLFMKKPDQDYRD---------NETDDIPETFHEDETDSNIQDKW---STRRAAVSGDNVVNEIELALEGVRRIVHHIKKENSYSAMRDDWKYVAVVLDRLFLWLFSIAAIIGMLGYLCR 466          

Query:  201 GFKSAVQLYQKLLDENNYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLYN 491
            G K A +LY  L+    Y+  +RPV+     V  Y  L L Q++D++ ++Q +  N+WV QEW D N  W+P DY  V  L+IPS +IW PD+VLYN
Sbjct:   16 GTKDARRLYDDLMRRRGYDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYN 112