Membrane protein insertase YidC

Overview
NameMembrane protein insertase YidC
Smed IDSMED30019526
Length (bp)1262
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Membrane protein insertase YidC (SMED30019526) t-SNE clustered cells

Violin plots show distribution of expression levels for Membrane protein insertase YidC (SMED30019526) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Membrane protein insertase YidC (SMED30019526) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Membrane protein insertase YidC (SMED30019526) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30019526

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 8

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30019526SMESG000039158.1 SmedASXL_008039SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
X2 cellSMED30019526SMESG000039158.1 SmedASXL_008039SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
pharynxSMED30019526SMESG000039158.1 dd_Smed_v4_4072_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30019526SMESG000039158.1 dd_Smed_v4_4072_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30019526SMESG000039158.1 dd_Smed_v4_4072_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30019526SMESG000039158.1 dd_Smed_v4_4072_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30019526SMESG000039158.1 dd_Smed_v4_4072_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30019526SMESG000039158.1 dd_Smed_v4_4072_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Membrane protein insertase YidC vs. Ensembl Human
Match: OXA1L (OXA1L mitochondrial inner membrane protein [Source:HGNC Symbol;Acc:HGNC:8526])

HSP 1 Score: 122.865 bits (307), Expect = 2.137e-30
Identity = 74/235 (31.49%), Postives = 123/235 (52.34%), Query Frame = 1 
Query:  508 PKIVDFDKKIHSARVANDSLSMAKLLHDQQKLLKNSEFSPIKSMIYSLLQIPVFLSVMIGLKNMAELPVASLQTGGAFWFTDLTMYDPYYILPVSTMMLLFLQLEVGADVKKNTNSGYLKWG---IRSLPIVALAFTCRLPSALLLYWWTSSCMSLVFSGIMSIPFVKTRLGLSALSYQAPTATDSKLGYLQNFKESNAEKRITK-LAKQYHNLEHENWIKARTSSIPKTYKYDP 1200
            P+I  F  +I  A++A D +   K   +     K       K +I  + Q P+F+S  I L+ MA LPV SLQTGG +WF DLT+ DP YILP++    ++  LE+GA+      S  L+W    IR +P++ L  T   P+A+ +YW +S+  SLV    + IP V+T L +             + G+L++FK+      +T+ L ++   + ++  + AR   + +T+ ++P
Sbjct:  158 PEIQKFSSRIREAKLAGDHIEYYKASSEMALYQKKHGIKLYKPLILPVTQAPIFISFFIALREMANLPVPSLQTGGLWWFQDLTVSDPIYILPLAVTATMWAVLELGAET--GVQSSDLQWMRNVIRMMPLITLPITMHFPTAVFMYWLSSNLFSLVQVSCLRIPAVRTVLKIPQRVVHDLDKLPPREGFLESFKKGWKNAEMTRQLREREQRMRNQLELAAR-GPLRQTFTHNP 389

HSP 2 Score: 56.6102 bits (135), Expect = 4.581e-8
Identity = 30/95 (31.58%), Postives = 43/95 (45.26%), Query Frame = 3 
Query:   96 HNVYILNRKLSDISNDKIKVSEMTTEMNADVSKYYXXXXXXXXXXXXKFLDLNHLGEPTFKSLGLNSYWPSGWVQHLYEIMHVDLGLPWWSTIVA 380
            H +++       +S   I  +E+  +    V+    P    +         +    E +F  LGL SY P G +Q+L E MHVDLGLPWW  I A
Sbjct:   36 HYLFLAASGPRSLSTSAISFAEVQVQAPPVVAATPSPTAVPEVASGETADVVQTAAEQSFAELGLGSYTPVGLIQNLLEFMHVDLGLPWWGAIAA 130
[Close]
BLAST of Membrane protein insertase YidC vs. Ensembl Human
Match: OXA1L (OXA1L mitochondrial inner membrane protein [Source:HGNC Symbol;Acc:HGNC:8526])

HSP 1 Score: 122.865 bits (307), Expect = 2.620e-30
Identity = 74/235 (31.49%), Postives = 123/235 (52.34%), Query Frame = 1 
Query:  508 PKIVDFDKKIHSARVANDSLSMAKLLHDQQKLLKNSEFSPIKSMIYSLLQIPVFLSVMIGLKNMAELPVASLQTGGAFWFTDLTMYDPYYILPVSTMMLLFLQLEVGADVKKNTNSGYLKWG---IRSLPIVALAFTCRLPSALLLYWWTSSCMSLVFSGIMSIPFVKTRLGLSALSYQAPTATDSKLGYLQNFKESNAEKRITK-LAKQYHNLEHENWIKARTSSIPKTYKYDP 1200
            P+I  F  +I  A++A D +   K   +     K       K +I  + Q P+F+S  I L+ MA LPV SLQTGG +WF DLT+ DP YILP++    ++  LE+GA+      S  L+W    IR +P++ L  T   P+A+ +YW +S+  SLV    + IP V+T L +             + G+L++FK+      +T+ L ++   + ++  + AR   + +T+ ++P
Sbjct:  174 PEIQKFSSRIREAKLAGDHIEYYKASSEMALYQKKHGIKLYKPLILPVTQAPIFISFFIALREMANLPVPSLQTGGLWWFQDLTVSDPIYILPLAVTATMWAVLELGAET--GVQSSDLQWMRNVIRMMPLITLPITMHFPTAVFMYWLSSNLFSLVQVSCLRIPAVRTVLKIPQRVVHDLDKLPPREGFLESFKKGWKNAEMTRQLREREQRMRNQLELAAR-GPLRQTFTHNP 405

HSP 2 Score: 56.6102 bits (135), Expect = 4.188e-8
Identity = 30/95 (31.58%), Postives = 43/95 (45.26%), Query Frame = 3 
Query:   96 HNVYILNRKLSDISNDKIKVSEMTTEMNADVSKYYXXXXXXXXXXXXKFLDLNHLGEPTFKSLGLNSYWPSGWVQHLYEIMHVDLGLPWWSTIVA 380
            H +++       +S   I  +E+  +    V+    P    +         +    E +F  LGL SY P G +Q+L E MHVDLGLPWW  I A
Sbjct:   52 HYLFLAASGPRSLSTSAISFAEVQVQAPPVVAATPSPTAVPEVASGETADVVQTAAEQSFAELGLGSYTPVGLIQNLLEFMHVDLGLPWWGAIAA 146
[Close]
BLAST of Membrane protein insertase YidC vs. Ensembl Human
Match: OXA1L (OXA1L mitochondrial inner membrane protein [Source:HGNC Symbol;Acc:HGNC:8526])

HSP 1 Score: 122.479 bits (306), Expect = 7.427e-30
Identity = 74/235 (31.49%), Postives = 123/235 (52.34%), Query Frame = 1 
Query:  508 PKIVDFDKKIHSARVANDSLSMAKLLHDQQKLLKNSEFSPIKSMIYSLLQIPVFLSVMIGLKNMAELPVASLQTGGAFWFTDLTMYDPYYILPVSTMMLLFLQLEVGADVKKNTNSGYLKWG---IRSLPIVALAFTCRLPSALLLYWWTSSCMSLVFSGIMSIPFVKTRLGLSALSYQAPTATDSKLGYLQNFKESNAEKRITK-LAKQYHNLEHENWIKARTSSIPKTYKYDP 1200
            P+I  F  +I  A++A D +   K   +     K       K +I  + Q P+F+S  I L+ MA LPV SLQTGG +WF DLT+ DP YILP++    ++  LE+GA+      S  L+W    IR +P++ L  T   P+A+ +YW +S+  SLV    + IP V+T L +             + G+L++FK+      +T+ L ++   + ++  + AR   + +T+ ++P
Sbjct:  234 PEIQKFSSRIREAKLAGDHIEYYKASSEMALYQKKHGIKLYKPLILPVTQAPIFISFFIALREMANLPVPSLQTGGLWWFQDLTVSDPIYILPLAVTATMWAVLELGAET--GVQSSDLQWMRNVIRMMPLITLPITMHFPTAVFMYWLSSNLFSLVQVSCLRIPAVRTVLKIPQRVVHDLDKLPPREGFLESFKKGWKNAEMTRQLREREQRMRNQLELAAR-GPLRQTFTHNP 465

HSP 2 Score: 56.6102 bits (135), Expect = 4.398e-8
Identity = 30/95 (31.58%), Postives = 43/95 (45.26%), Query Frame = 3 
Query:   96 HNVYILNRKLSDISNDKIKVSEMTTEMNADVSKYYXXXXXXXXXXXXKFLDLNHLGEPTFKSLGLNSYWPSGWVQHLYEIMHVDLGLPWWSTIVA 380
            H +++       +S   I  +E+  +    V+    P    +         +    E +F  LGL SY P G +Q+L E MHVDLGLPWW  I A
Sbjct:  112 HYLFLAASGPRSLSTSAISFAEVQVQAPPVVAATPSPTAVPEVASGETADVVQTAAEQSFAELGLGSYTPVGLIQNLLEFMHVDLGLPWWGAIAA 206
[Close]
BLAST of Membrane protein insertase YidC vs. Ensembl Human
Match: OXA1L (OXA1L mitochondrial inner membrane protein [Source:HGNC Symbol;Acc:HGNC:8526])

HSP 1 Score: 119.013 bits (297), Expect = 4.318e-29
Identity = 69/204 (33.82%), Postives = 106/204 (51.96%), Query Frame = 1 
Query:  508 PKIVDFDKKIHSARVANDSLSMAKLLHDQQKLLKNSEFSPIKSMIYSLLQIPVFLSVMIGLKNMAELPVASLQTGGAFWFTDLTMYDPYYILPVSTMMLLFLQLEVGADVKKNTNSGYLKWG---IRSLPIVALAFTCRLPSALLLYWWTSSCMSLVFSGIMSIPFVKTRLGLSALSYQAPTATDSKLGYLQNFKESNAEKRIT 1110
            P+I  F  +I  A++A D +   K   +     K       K +I  + Q P+F+S  I L+ MA LPV SLQTGG +WF DLT+ DP YILP++    ++  LE+GA+      S  L+W    IR +P++ L  T   P+A+ +YW +S+  SLV    + IP V+T L +             + G+L++FK+    +  T
Sbjct:  174 PEIQKFSSRIREAKLAGDHIEYYKASSEMALYQKKHGIKLYKPLILPVTQAPIFISFFIALREMANLPVPSLQTGGLWWFQDLTVSDPIYILPLAVTATMWAVLELGAET--GVQSSDLQWMRNVIRMMPLITLPITMHFPTAVFMYWLSSNLFSLVQVSCLRIPAVRTVLKIPQRVVHDLDKLPPREGFLESFKKGPLRQTFT 375

HSP 2 Score: 56.9954 bits (136), Expect = 3.482e-8
Identity = 30/95 (31.58%), Postives = 43/95 (45.26%), Query Frame = 3 
Query:   96 HNVYILNRKLSDISNDKIKVSEMTTEMNADVSKYYXXXXXXXXXXXXKFLDLNHLGEPTFKSLGLNSYWPSGWVQHLYEIMHVDLGLPWWSTIVA 380
            H +++       +S   I  +E+  +    V+    P    +         +    E +F  LGL SY P G +Q+L E MHVDLGLPWW  I A
Sbjct:   52 HYLFLAASGPRSLSTSAISFAEVQVQAPPVVAATPSPTAVPEVASGETADVVQTAAEQSFAELGLGSYTPVGLIQNLLEFMHVDLGLPWWGAIAA 146
[Close]
BLAST of Membrane protein insertase YidC vs. Ensembl Human
Match: COX18 (cytochrome c oxidase assembly factor COX18 [Source:HGNC Symbol;Acc:HGNC:26801])

HSP 1 Score: 59.6918 bits (143), Expect = 3.249e-9
Identity = 43/168 (25.60%), Postives = 81/168 (48.21%), Query Frame = 1 
Query:  625 PIKSMIYSLLQIPVFLSVMIGLKNMAELPVAS--------LQTGGAFWFTDLTMYDPYYILPVSTMMLLFLQLEVGA--DVKKNTNSGYLKWGIRSLPIVALAFTCRLPSALLLYWWTSSCMSLVFSGIMSIPFVKTRLGLSALSYQAPTATDSKLGYLQNFKESNAE 1098
            P K+ +   +Q+P+++ +   L+N++     S        L TGG  WF DLT  D  +ILP+S  ++  L +E+ A   +  +    Y+ + +R++ ++ +     +PS+++LYW  SS + L  + ++  P      G   L     T +DS+  Y   F   N +
Sbjct:  167 PFKATVLVWIQLPMWIFMSFALRNLSTGAAHSEGFSVQEQLATGGILWFPDLTAPDSTWILPISVGVINLLIVEICALQKIGMSRFQTYITYFVRAMSVLMIPIAATVPSSIVLYWLCSSFVGLSQNLLLRSP------GFRQLCRIPSTKSDSETPYKDIFAAFNTK 328
[Close]
BLAST of Membrane protein insertase YidC vs. Ensembl Celegans
Match: oxa-1 (OXA mitochondrial inner membrane insertase homolog [Source:UniProtKB/TrEMBL;Acc:O02207])

HSP 1 Score: 72.7886 bits (177), Expect = 7.557e-14
Identity = 48/200 (24.00%), Postives = 94/200 (47.00%), Query Frame = 1 
Query:  520 DFDKKIHSARVANDSLSMAKLLHDQQKLLKNSEFSPIKSMIYSLLQIPVFLSVMIGLKNMAELPVASLQTGGAFWFTDLTMYDPYYILPVSTMMLLFLQLEVGADVKKNTNS------GYLKWGIRSLPIVALAFTCRLPSALLLYWWTSSCMSLVFSGIMSIPFVKTRLGLSALSYQAPTATDSKL--GYLQNFKESNA 1095
            +F  +I  AR  N+ L   ++L +Q+  L++ +    +  +       VF +    +K M  +    L TGG  WFTDLT  DPYY LP  +   + L  +VG ++  + +        ++ +G   LP+V    + +  + L +YW  S+ +SL+++    +  ++   G+  +    P+A         L+++K++ A
Sbjct:  144 EFRDRIDEARKENNQLLQQQILLEQRDFLRSKDIRLGRQFMVMAANGAVFATQFFAIKKMVVVNYPGLSTGGTLWFTDLTATDPYYALPFISAATMALVTKVGIEMGTSADQMPPIMRAFMTYG---LPVVIFGVSSQFATGLCVYWTASNAVSLIYAAAFKVDAIRKIFGIPPVVPLPPSAVQKNAISQVLKSYKDNKA 340
[Close]
BLAST of Membrane protein insertase YidC vs. Ensembl Fly
Match: OXA1L (gene:FBgn0027615 transcript:FBtr0076271)

HSP 1 Score: 162.155 bits (409), Expect = 6.844e-45
Identity = 83/236 (35.17%), Postives = 135/236 (57.20%), Query Frame = 1 
Query:  508 PKIVDFDKKIHSARVANDSLSMAKLLHDQQKLLKNSEFSPIKSMIYSLLQIPVFLSVMIGLKNMAELPVASLQTGGAFWFTDLTMYDPYYILPVSTMMLLFLQLEVGADVKK--NTNSGYLKWGIRSLPIVALAFTCRLPSALLLYWWTSSCMSLVFSGIMSIPFVKTRLGLSALSYQAPTATDSKLGYLQNFKESNAEKRITKLAKQYHNLEHENWIKARTSSIPKTYKYDPTKV 1209
            P++     K+  AR + +++  A+   +    ++    +P+K+M+  L Q P+F+S  +GL+ MA  PV S++ GG FWFTDLTM DP+Y+LP+ T   L+L +E+G D  +    N   +K+ +R+LPIV   FT   P+A+L YW  S+ +SL    ++ IP V+    +  +   AP+A   K G++   KES    +I+K  ++   L+   + KA    + KTYK+DPTKV
Sbjct:  186 PQMQMLQLKMTEARQSGNAIESARYAQEMMLFMREKGVNPLKNMVVPLAQAPLFISFFMGLRQMANAPVESMRDGGLFWFTDLTMADPFYLLPLITSATLYLTIEIGTDSARLSAANMNTMKYVLRALPIVIFPFTMNFPAAILTYWACSNFISLGQVAVLRIPSVREYFKIEKMLTHAPSALPPKKGFVGGMKESWDNMKISKEIEERQRLDEIRFAKAGKGPLVKTYKFDPTKV 421

HSP 2 Score: 48.1358 bits (113), Expect = 9.605e-6
Identity = 19/43 (44.19%), Postives = 26/43 (60.47%), Query Frame = 3 
Query:  249 LNHLGEPTFKSLGLNSYWPSGWVQHLYEIMHVDLGLPWWSTIV 377
            +N  GEP+F S+GL  + P G VQ+  E +H    +PWW TI 
Sbjct:  115 MNAAGEPSFASIGLGGWSPVGMVQNCLEFLHCTWDIPWWGTIA 157
[Close]
BLAST of Membrane protein insertase YidC vs. Ensembl Fly
Match: OXA1L (gene:FBgn0027615 transcript:FBtr0076272)

HSP 1 Score: 162.155 bits (409), Expect = 6.844e-45
Identity = 83/236 (35.17%), Postives = 135/236 (57.20%), Query Frame = 1 
Query:  508 PKIVDFDKKIHSARVANDSLSMAKLLHDQQKLLKNSEFSPIKSMIYSLLQIPVFLSVMIGLKNMAELPVASLQTGGAFWFTDLTMYDPYYILPVSTMMLLFLQLEVGADVKK--NTNSGYLKWGIRSLPIVALAFTCRLPSALLLYWWTSSCMSLVFSGIMSIPFVKTRLGLSALSYQAPTATDSKLGYLQNFKESNAEKRITKLAKQYHNLEHENWIKARTSSIPKTYKYDPTKV 1209
            P++     K+  AR + +++  A+   +    ++    +P+K+M+  L Q P+F+S  +GL+ MA  PV S++ GG FWFTDLTM DP+Y+LP+ T   L+L +E+G D  +    N   +K+ +R+LPIV   FT   P+A+L YW  S+ +SL    ++ IP V+    +  +   AP+A   K G++   KES    +I+K  ++   L+   + KA    + KTYK+DPTKV
Sbjct:  186 PQMQMLQLKMTEARQSGNAIESARYAQEMMLFMREKGVNPLKNMVVPLAQAPLFISFFMGLRQMANAPVESMRDGGLFWFTDLTMADPFYLLPLITSATLYLTIEIGTDSARLSAANMNTMKYVLRALPIVIFPFTMNFPAAILTYWACSNFISLGQVAVLRIPSVREYFKIEKMLTHAPSALPPKKGFVGGMKESWDNMKISKEIEERQRLDEIRFAKAGKGPLVKTYKFDPTKV 421

HSP 2 Score: 48.1358 bits (113), Expect = 9.605e-6
Identity = 19/43 (44.19%), Postives = 26/43 (60.47%), Query Frame = 3 
Query:  249 LNHLGEPTFKSLGLNSYWPSGWVQHLYEIMHVDLGLPWWSTIV 377
            +N  GEP+F S+GL  + P G VQ+  E +H    +PWW TI 
Sbjct:  115 MNAAGEPSFASIGLGGWSPVGMVQNCLEFLHCTWDIPWWGTIA 157
[Close]
BLAST of Membrane protein insertase YidC vs. Ensembl Fly
Match: CG4942 (gene:FBgn0035960 transcript:FBtr0076524)

HSP 1 Score: 60.4622 bits (145), Expect = 9.797e-10
Identity = 42/155 (27.10%), Postives = 73/155 (47.10%), Query Frame = 1 
Query:  595 QKLLKNSEFSPIKSMIYSLLQIPVFLSVMIGLKNM-----------AELPVASLQTGGAFWFTDLTMYDPYYILPVSTMMLLFLQLEVGADVKKNTNSGYLKWG---IRSLPIVALAFTCRLPSALLLYWWTSSCMSLVFSGIMSIPFVKTRLGL 1017
            Q L+      P+K+MI    QIP+++   + L+N+           A++    +  GG  W  +LT+ D  YILPV+  ++    +EV A  +   ++          R L +V +   C +PSAL +YW  SS   L  + ++  P V+  +G+
Sbjct:  161 QNLIVRDNCHPMKTMIVLWGQIPLWIFQSVALRNLVYMLPDPTSIQAQIVTTEMTIGGFGWIPNLTVVDNSYILPVALGLINLAIIEVQAMSRTRPSTRLQNIANNVFRGLSVVMVPVACTVPSALCVYWVASSSFGLAQNLLILSPEVRRSVGI 315
[Close]
BLAST of Membrane protein insertase YidC vs. Ensembl Zebrafish
Match: oxa1l (OXA1L mitochondrial inner membrane protein [Source:ZFIN;Acc:ZDB-GENE-071004-49])

HSP 1 Score: 122.479 bits (306), Expect = 7.477e-36
Identity = 75/241 (31.12%), Postives = 120/241 (49.79%), Query Frame = 1 
Query:  502 ISPKIVDFDKKIHSARVANDSLSMAKLLHDQQKLLKNSEFSPIKSMIYSLLQIPVFLSVMIGLKNMAELPVASLQTGGAFWFTDLTMYDPYYILPVSTMMLLFLQLEVGADVK-KNTNSGYLKWGIRSLPIVALAFTCRLPSALLLYWWTSSCMSLVFSGIMSIPFVKTRLGLSALSYQAPTATDSKLGYLQNFKES--NAEKRITKLAKQYHNLEHENWIK-----ARTSSIPKTYKYDP 1200
            + P++     +++ A+ + +    +K   D     K  + +P +  +  L+Q P+FLS  I L+ M+ELPV SLQTGG +WFTDLT  DP+YILP++    +   LE+GA+    N N   +K   R +P V L  T   P+A+  YW TS+  SL    ++  P V+ +L +        +A     G+    K+   NA+     LA+Q    E E  IK     A    + +T+ ++P
Sbjct:  207 VMPEMTKLTNRMNEAKQSGNKFEFSKAYTDLMMFQKKKDVNPFRGFLVPLVQAPIFLSFFIALRKMSELPVPSLQTGGLWWFTDLTAADPFYILPIAVTGTMVAILELGAESGVDNPNLRAMKTVFRIMPFVILPLTINFPTAVFTYWMTSNLFSLAQVAVLRHPAVRQKLRIPERIVHPQSALPENEGFFATVKKGWKNAQ-----LAQQLE--ERERRIKGHLDIAAKGPLRQTFTHNP 440

HSP 2 Score: 48.1358 bits (113), Expect = 7.477e-36
Identity = 22/54 (40.74%), Postives = 30/54 (55.56%), Query Frame = 3 
Query:  261 GEPTFKSLGLNSYWPSGWVQHLYEIMHVDLGLPWWSTIVASRFPMGNIYIFKVL 422
             E +   LGL +  P G +Q+L E MHV +GLPWW  IVA    +    +F V+
Sbjct:  142 AEASLSELGLCNSTPVGLIQNLLEFMHVSIGLPWWGAIVAGTI-VARCAVFPVI 194
[Close]
BLAST of Membrane protein insertase YidC vs. Ensembl Zebrafish
Match: oxa1l (OXA1L mitochondrial inner membrane protein [Source:ZFIN;Acc:ZDB-GENE-071004-49])

HSP 1 Score: 122.479 bits (306), Expect = 7.477e-36
Identity = 75/241 (31.12%), Postives = 120/241 (49.79%), Query Frame = 1 
Query:  502 ISPKIVDFDKKIHSARVANDSLSMAKLLHDQQKLLKNSEFSPIKSMIYSLLQIPVFLSVMIGLKNMAELPVASLQTGGAFWFTDLTMYDPYYILPVSTMMLLFLQLEVGADVK-KNTNSGYLKWGIRSLPIVALAFTCRLPSALLLYWWTSSCMSLVFSGIMSIPFVKTRLGLSALSYQAPTATDSKLGYLQNFKES--NAEKRITKLAKQYHNLEHENWIK-----ARTSSIPKTYKYDP 1200
            + P++     +++ A+ + +    +K   D     K  + +P +  +  L+Q P+FLS  I L+ M+ELPV SLQTGG +WFTDLT  DP+YILP++    +   LE+GA+    N N   +K   R +P V L  T   P+A+  YW TS+  SL    ++  P V+ +L +        +A     G+    K+   NA+     LA+Q    E E  IK     A    + +T+ ++P
Sbjct:  207 VMPEMTKLTNRMNEAKQSGNKFEFSKAYTDLMMFQKKKDVNPFRGFLVPLVQAPIFLSFFIALRKMSELPVPSLQTGGLWWFTDLTAADPFYILPIAVTGTMVAILELGAESGVDNPNLRAMKTVFRIMPFVILPLTINFPTAVFTYWMTSNLFSLAQVAVLRHPAVRQKLRIPERIVHPQSALPENEGFFATVKKGWKNAQ-----LAQQLE--ERERRIKGHLDIAAKGPLRQTFTHNP 440

HSP 2 Score: 48.1358 bits (113), Expect = 7.477e-36
Identity = 22/54 (40.74%), Postives = 30/54 (55.56%), Query Frame = 3 
Query:  261 GEPTFKSLGLNSYWPSGWVQHLYEIMHVDLGLPWWSTIVASRFPMGNIYIFKVL 422
             E +   LGL +  P G +Q+L E MHV +GLPWW  IVA    +    +F V+
Sbjct:  142 AEASLSELGLCNSTPVGLIQNLLEFMHVSIGLPWWGAIVAGTI-VARCAVFPVI 194
[Close]
BLAST of Membrane protein insertase YidC vs. Ensembl Zebrafish
Match: cox18 (cytochrome c oxidase assembly factor COX18 [Source:ZFIN;Acc:ZDB-GENE-080204-88])

HSP 1 Score: 66.2402 bits (160), Expect = 1.255e-11
Identity = 44/168 (26.19%), Postives = 86/168 (51.19%), Query Frame = 1 
Query:  625 PIKSMIYSLLQIPVFLSVMIGLKNMA-----ELPVASLQTGGAFWFTDLTMYDPYYILPVSTMMLLFLQLEVGADVKKNTNSGYLKWG---IRSLPIVALAFTCRLPSALLLYWWTSSCMSLVFSGIMSIPFVK--TRLGLSALSYQAPTATDSKLGYLQNFKESNAE 1098
            P K+ +   +Q+P+++ V + L+N++         A L  GGA WF DLT+ D  +I+PVS  ++  L  E+ A +++  +S   K+    IR + ++ +     +PS++ +YW +SSC+ L  + ++  P V+   R+  +    Q P   D    ++  +  + A 
Sbjct:  160 PFKASVLIWVQLPMWVCVSLALRNLSLGLGNTDVSAGLAAGGALWFPDLTVPDSTWIMPVSLGIINLLITEIFA-LRQTESSKMQKYATHFIRGISVLMIPIAATVPSSMCVYWLSSSCVGLAHNLLLRSPGVRKLCRIPETRFDSQTPY-RDIAAAFIHKYSRAGAH 325
[Close]
BLAST of Membrane protein insertase YidC vs. Ensembl Xenopus
Match: mpp2 (membrane protein, palmitoylated 2 [Source:Xenbase;Acc:XB-GENE-961053])

HSP 1 Score: 124.405 bits (311), Expect = 1.089e-34
Identity = 65/238 (27.31%), Postives = 128/238 (53.78%), Query Frame = 1 
Query:  490 INSYISPKIVDFDKKIHSARVANDSLSMAKLLHDQQKLLKNSEFSPIKSMIYSLLQIPVFLSVMIGLKNMAELPVASLQTGGAFWFTDLTMYDPYYILPVSTMMLLFLQLEVGADVK-KNTNSGYLKWGIRSLPIVALAFTCRLPSALLLYWWTSSCMSLVFSGIMSIPFVKTRLGLSALSYQAPTATDSKLGYLQNFKESNAEKRITKLAKQYHNLEHENWIKARTSSIPKTYKYDP 1200
            +N+++ P+I     +++ A+ + +    +K   D     K  + +P++  +  L+Q P+F+S  + L+ M+ LPV S+Q+GG +WFTDLT  DP+YILP++    ++  LE+GA+    N N   +K   R +P++ L  T   P+A+  YW TS+  SL     + IP V+ +L +        +A   + G+++N K+   ++   ++  +      ++  +A T  + +T+ ++P
Sbjct:  165 LNNHM-PQISSMTNRMNEAKQSGNKFEFSKAYSDLTLYQKKHDVNPLRGFLVPLVQAPIFISFFVALRQMSYLPVPSMQSGGLWWFTDLTAADPFYILPLTVTCTMWGVLELGAESGVDNPNLKIMKTVFRVMPLIILPLTINFPTAVFTYWVTSNVFSLAQVSFLRIPAVRKKLKIPERIKHDASALPPQEGFIKNLKKDWEQQHQVQVFFEVQRTHQDSLPQAITGPMRQTFSHNP 401

HSP 2 Score: 43.1282 bits (100), Expect = 1.089e-34
Identity = 18/51 (35.29%), Postives = 28/51 (54.90%), Query Frame = 3 
Query:  270 TFKSLGLNSYWPSGWVQHLYEIMHVDLGLPWWSTIVASRFPMGNIYIFKVL 422
            +   LGL    P G +Q+  E ++VD+GLPWW  IV     +  I +F ++
Sbjct:  106 SLADLGLGGQTPVGLIQNFLEFLNVDVGLPWWGAIVTGTV-LARILVFPLI 155
[Close]
BLAST of Membrane protein insertase YidC vs. Ensembl Xenopus
Match: mpp2 (membrane protein, palmitoylated 2 [Source:Xenbase;Acc:XB-GENE-961053])

HSP 1 Score: 118.627 bits (296), Expect = 5.729e-33
Identity = 60/195 (30.77%), Postives = 106/195 (54.36%), Query Frame = 1 
Query:  508 PKIVDFDKKIHSARVANDSLSMAKLLHDQQKLLKNSEFSPIKSMIYSLLQIPVFLSVMIGLKNMAELPVASLQTGGAFWFTDLTMYDPYYILPVSTMMLLFLQLEVGADVK-KNTNSGYLKWGIRSLPIVALAFTCRLPSALLLYWWTSSCMSLVFSGIMSIPFVKTRLGLSALSYQAPTATDSKLGYLQNFKES 1089
            P+I     +++ A+ + +    +K   D     K  + +P++  +  L+Q P+F+S  + L+ M+ LPV S+Q+GG +WFTDLT  DP+YILP++    ++  LE+GA+    N N   +K   R +P++ L  T   P+A+  YW TS+  SL     + IP V+ +L +        +A   + G+++N K+ 
Sbjct:  170 PQISSMTNRMNEAKQSGNKFEFSKAYSDLTLYQKKHDVNPLRGFLVPLVQAPIFISFFVALRQMSYLPVPSMQSGGLWWFTDLTAADPFYILPLTVTCTMWGVLELGAESGVDNPNLKIMKTVFRVMPLIILPLTINFPTAVFTYWVTSNVFSLAQVSFLRIPAVRKKLKIPERIKHDASALPPQEGFIKNLKKG 364

HSP 2 Score: 43.1282 bits (100), Expect = 5.729e-33
Identity = 18/51 (35.29%), Postives = 28/51 (54.90%), Query Frame = 3 
Query:  270 TFKSLGLNSYWPSGWVQHLYEIMHVDLGLPWWSTIVASRFPMGNIYIFKVL 422
            +   LGL    P G +Q+  E ++VD+GLPWW  IV     +  I +F ++
Sbjct:  106 SLADLGLGGQTPVGLIQNFLEFLNVDVGLPWWGAIVTGTV-LARILVFPLI 155
[Close]
BLAST of Membrane protein insertase YidC vs. Ensembl Xenopus
Match: cox18 (cytochrome c oxidase assembly factor COX18 [Source:NCBI gene;Acc:549087])

HSP 1 Score: 61.6178 bits (148), Expect = 9.249e-10
Identity = 44/138 (31.88%), Postives = 74/138 (53.62%), Query Frame = 1 
Query:  625 PIKSMIYSLLQIPVFLSVMIGLKNMA---------ELPVASLQTGGAFWFTDLTMYDPYYILPVSTMMLLFLQLEVGADVKKNTNSGYLKW---GIRSLPIVALAFTCRLPSALLLYWWTSSCMSLVFSGIMSIPFVK 1002
            P K+ +   +QIP+++ V I L+N++         +     L  GG  WF DLTM D  +ILPV+  +L  L +E+ A ++K   S + K     IR++ I  +     +PS++ LYW TSSC+ L  + ++  P ++
Sbjct:  214 PFKASLLIWIQIPMWIFVSIALRNISLNRADSATGDAVQKQLTEGGLLWFPDLTMPDSTWILPVTLGLLNLLIVEIFA-LRKIELSRFQKIITNFIRAVSIAMIPIASTVPSSMALYWVTSSCVGLAHNLLLRSPALR 350
[Close]
BLAST of Membrane protein insertase YidC vs. Ensembl Mouse
Match: Oxa1l (oxidase assembly 1-like [Source:MGI Symbol;Acc:MGI:1916339])

HSP 1 Score: 131.339 bits (329), Expect = 1.729e-33
Identity = 71/232 (30.60%), Postives = 120/232 (51.72%), Query Frame = 1 
Query:  508 PKIVDFDKKIHSARVANDSLSMAKLLHDQQKLLKNSEFSPIKSMIYSLLQIPVFLSVMIGLKNMAELPVASLQTGGAFWFTDLTMYDPYYILPVSTMMLLFLQLEVGADVKKNTNS-GYLKWGIRSLPIVALAFTCRLPSALLLYWWTSSCMSLVFSGIMSIPFVKTRLGLSALSYQAPTATDSKLGYLQNFKESNAEKRITKLAKQYHNLEHENWIKARTSSIPKTYKYDP 1200
            P++  F  +I  A++A D     K   +  +  K  +   ++ +I  L Q PVF+S  I L+ MA LPV SLQTGG +WF DLT+ DP Y+LP+     ++  LE+GA+    +N   +++  IR +P+V L  T   PSA+ +YW +S+  SL     + IP V+T L +       P     + G+L++FK+      I +  ++      ++   A    + +T+ ++P
Sbjct:  169 PEMQKFSARIREAKLAGDQAEFYKATIEMTRYQKKHDIKLLRPLILPLTQAPVFISFFIALREMANLPVPSLQTGGLWWFQDLTVSDPIYVLPLVVTATMWCVLELGAETGVQSNDLQFMRNIIRVMPLVVLPVTIHFPSAVFMYWLSSNVFSLCQVACLRIPAVRTVLKIPQRVVHDPDKLPPREGFLKSFKKGWKNAEIAQQLREREQRMQKHLDLAARGPLRQTFTHNP 400

HSP 2 Score: 56.225 bits (134), Expect = 3.604e-8
Identity = 23/38 (60.53%), Postives = 27/38 (71.05%), Query Frame = 3 
Query:  264 EPTFKSLGLNSYWPSGWVQHLYEIMHVDLGLPWWSTIV 377
            EP+F  LGL SY P G +Q+L E +HVDLGLPWW  I 
Sbjct:  103 EPSFTELGLGSYTPVGLIQNLLEYIHVDLGLPWWGAIA 140
[Close]
BLAST of Membrane protein insertase YidC vs. Ensembl Mouse
Match: Cox18 (cytochrome c oxidase assembly protein 18 [Source:MGI Symbol;Acc:MGI:2448532])

HSP 1 Score: 67.3958 bits (163), Expect = 6.339e-12
Identity = 57/210 (27.14%), Postives = 101/210 (48.10%), Query Frame = 1 
Query:  502 ISPKIVDFDKKIH-----SARVANDSLSMAKL--LHDQQKLLKN----SEFSPIKSMIYSLLQIPVFLSVMIGLKNMAELPVAS--------LQTGGAFWFTDLTMYDPYYILPVSTMMLLFLQLEVGADVKKNTN--SGYLKWGIRSLPIVALAFTCRLPSALLLYWWTSSCMSLVFSGIMSIPFVKTRLGLSALSYQAPTATDSKLGY 1068
            + P+I D  K+++      AR    S  +A+L  L + ++L+          P K+ +   +Q+P+++ + + L+N++     S        L  GG  WF DLT  D  +ILPVS  ++  L +E+ A  K  T+    Y+   +R++ ++ +     +PSAL+LYW  SS M L  + ++  P      G   L    P+ +DS+  Y
Sbjct:  112 LQPEIKDIAKRLNQEVAVCARQFGWSKRVARLTYLKNMRRLISELYVRDNCHPFKATVLVWVQLPMWVFISVALRNLSTGATHSDGISVQEQLAAGGTLWFPDLTAVDSTWILPVSVGVVNLLIVEIFALQKIGTSRFQMYVTNFVRAVSVLMIPVAATVPSALVLYWLCSSLMGLAQNLLLRSP------GFRQLCRIPPSKSDSETPY 315

HSP 2 Score: 22.7126 bits (47), Expect = 6.339e-12
Identity = 13/39 (33.33%), Postives = 15/39 (38.46%), Query Frame = 3 
Query:  303 PSGWVQHLYEIMHVDL------------GLPWWSTIVAS 383
            P GW + L     V              GLPWWS I+ S
Sbjct:   48 PGGWYEALAASAPVRTAEEVLLGAQEATGLPWWSNIILS 86
[Close]
BLAST of Membrane protein insertase YidC vs. Ensembl Mouse
Match: Cox18 (cytochrome c oxidase assembly protein 18 [Source:MGI Symbol;Acc:MGI:2448532])

HSP 1 Score: 67.0106 bits (162), Expect = 7.963e-12
Identity = 57/211 (27.01%), Postives = 101/211 (47.87%), Query Frame = 1 
Query:  502 ISPKIVDFDKKIH-----SARVANDSLSMAKL--LHDQQKLLKN----SEFSPIKSMIYSLLQIPVFLSVMIGLKNMAELPVAS---------LQTGGAFWFTDLTMYDPYYILPVSTMMLLFLQLEVGADVKKNTN--SGYLKWGIRSLPIVALAFTCRLPSALLLYWWTSSCMSLVFSGIMSIPFVKTRLGLSALSYQAPTATDSKLGY 1068
            + P+I D  K+++      AR    S  +A+L  L + ++L+          P K+ +   +Q+P+++ + + L+N++     S         L  GG  WF DLT  D  +ILPVS  ++  L +E+ A  K  T+    Y+   +R++ ++ +     +PSAL+LYW  SS M L  + ++  P      G   L    P+ +DS+  Y
Sbjct:  112 LQPEIKDIAKRLNQEVAVCARQFGWSKRVARLTYLKNMRRLISELYVRDNCHPFKATVLVWVQLPMWVFISVALRNLSTGATHSDAGISVQEQLAAGGTLWFPDLTAVDSTWILPVSVGVVNLLIVEIFALQKIGTSRFQMYVTNFVRAVSVLMIPVAATVPSALVLYWLCSSLMGLAQNLLLRSP------GFRQLCRIPPSKSDSETPY 316

HSP 2 Score: 22.7126 bits (47), Expect = 7.963e-12
Identity = 13/39 (33.33%), Postives = 15/39 (38.46%), Query Frame = 3 
Query:  303 PSGWVQHLYEIMHVDL------------GLPWWSTIVAS 383
            P GW + L     V              GLPWWS I+ S
Sbjct:   48 PGGWYEALAASAPVRTAEEVLLGAQEATGLPWWSNIILS 86
[Close]
BLAST of Membrane protein insertase YidC vs. Ensembl Mouse
Match: Oxa1l (oxidase assembly 1-like [Source:MGI Symbol;Acc:MGI:1916339])

HSP 1 Score: 51.2174 bits (121), Expect = 1.359e-7
Identity = 30/93 (32.26%), Postives = 46/93 (49.46%), Query Frame = 1 
Query:  874 IRSLPIVALAFTCRLPSALLLYWWTSSCMSLVFSGIMSIPFVKTRLGLSALSYQAPTATDSKLGYLQNFKES--NAEKRITKLAKQYHNLEHE 1146
            IR +P+V L  T   PSA+ +YW +S+  SL     + IP V+T L +       P     + G+L++FK+   NAE     +A+Q    E  
Sbjct:    5 IRVMPLVVLPVTIHFPSAVFMYWLSSNVFSLCQVACLRIPAVRTVLKIPQRVVHDPDKLPPREGFLKSFKKGWKNAE-----IAQQLREREQR 92
[Close]
BLAST of Membrane protein insertase YidC vs. UniProt/SwissProt
Match: sp|Q8BGA9|OXA1L_MOUSE (Mitochondrial inner membrane protein OXA1L OS=Mus musculus OX=10090 GN=Oxa1l PE=1 SV=1)

HSP 1 Score: 131.339 bits (329), Expect = 1.210e-32
Identity = 71/232 (30.60%), Postives = 120/232 (51.72%), Query Frame = 1 
Query:  508 PKIVDFDKKIHSARVANDSLSMAKLLHDQQKLLKNSEFSPIKSMIYSLLQIPVFLSVMIGLKNMAELPVASLQTGGAFWFTDLTMYDPYYILPVSTMMLLFLQLEVGADVKKNTNS-GYLKWGIRSLPIVALAFTCRLPSALLLYWWTSSCMSLVFSGIMSIPFVKTRLGLSALSYQAPTATDSKLGYLQNFKESNAEKRITKLAKQYHNLEHENWIKARTSSIPKTYKYDP 1200
            P++  F  +I  A++A D     K   +  +  K  +   ++ +I  L Q PVF+S  I L+ MA LPV SLQTGG +WF DLT+ DP Y+LP+     ++  LE+GA+    +N   +++  IR +P+V L  T   PSA+ +YW +S+  SL     + IP V+T L +       P     + G+L++FK+      I +  ++      ++   A    + +T+ ++P
Sbjct:  169 PEMQKFSARIREAKLAGDQAEFYKATIEMTRYQKKHDIKLLRPLILPLTQAPVFISFFIALREMANLPVPSLQTGGLWWFQDLTVSDPIYVLPLVVTATMWCVLELGAETGVQSNDLQFMRNIIRVMPLVVLPVTIHFPSAVFMYWLSSNVFSLCQVACLRIPAVRTVLKIPQRVVHDPDKLPPREGFLKSFKKGWKNAEIAQQLREREQRMQKHLDLAARGPLRQTFTHNP 400

HSP 2 Score: 56.225 bits (134), Expect = 2.521e-7
Identity = 23/38 (60.53%), Postives = 27/38 (71.05%), Query Frame = 3 
Query:  264 EPTFKSLGLNSYWPSGWVQHLYEIMHVDLGLPWWSTIV 377
            EP+F  LGL SY P G +Q+L E +HVDLGLPWW  I 
Sbjct:  103 EPSFTELGLGSYTPVGLIQNLLEYIHVDLGLPWWGAIA 140
[Close]
BLAST of Membrane protein insertase YidC vs. UniProt/SwissProt
Match: sp|Q15070|OXA1L_HUMAN (Mitochondrial inner membrane protein OXA1L OS=Homo sapiens OX=9606 GN=OXA1L PE=1 SV=3)

HSP 1 Score: 122.865 bits (307), Expect = 1.309e-29
Identity = 74/235 (31.49%), Postives = 123/235 (52.34%), Query Frame = 1 
Query:  508 PKIVDFDKKIHSARVANDSLSMAKLLHDQQKLLKNSEFSPIKSMIYSLLQIPVFLSVMIGLKNMAELPVASLQTGGAFWFTDLTMYDPYYILPVSTMMLLFLQLEVGADVKKNTNSGYLKWG---IRSLPIVALAFTCRLPSALLLYWWTSSCMSLVFSGIMSIPFVKTRLGLSALSYQAPTATDSKLGYLQNFKESNAEKRITK-LAKQYHNLEHENWIKARTSSIPKTYKYDP 1200
            P+I  F  +I  A++A D +   K   +     K       K +I  + Q P+F+S  I L+ MA LPV SLQTGG +WF DLT+ DP YILP++    ++  LE+GA+      S  L+W    IR +P++ L  T   P+A+ +YW +S+  SLV    + IP V+T L +             + G+L++FK+      +T+ L ++   + ++  + AR   + +T+ ++P
Sbjct:  174 PEIQKFSSRIREAKLAGDHIEYYKASSEMALYQKKHGIKLYKPLILPVTQAPIFISFFIALREMANLPVPSLQTGGLWWFQDLTVSDPIYILPLAVTATMWAVLELGAET--GVQSSDLQWMRNVIRMMPLITLPITMHFPTAVFMYWLSSNLFSLVQVSCLRIPAVRTVLKIPQRVVHDLDKLPPREGFLESFKKGWKNAEMTRQLREREQRMRNQLELAAR-GPLRQTFTHNP 405

HSP 2 Score: 56.6102 bits (135), Expect = 2.029e-7
Identity = 30/95 (31.58%), Postives = 43/95 (45.26%), Query Frame = 3 
Query:   96 HNVYILNRKLSDISNDKIKVSEMTTEMNADVSKYYXXXXXXXXXXXXKFLDLNHLGEPTFKSLGLNSYWPSGWVQHLYEIMHVDLGLPWWSTIVA 380
            H +++       +S   I  +E+  +    V+    P    +         +    E +F  LGL SY P G +Q+L E MHVDLGLPWW  I A
Sbjct:   52 HYLFLAASGPRSLSTSAISFAEVQVQAPPVVAATPSPTAVPEVASGETADVVQTAAEQSFAELGLGSYTPVGLIQNLLEFMHVDLGLPWWGAIAA 146
[Close]
BLAST of Membrane protein insertase YidC vs. UniProt/SwissProt
Match: sp|Q3SYV3|OXA1L_BOVIN (Mitochondrial inner membrane protein OXA1L OS=Bos taurus OX=9913 GN=OXA1L PE=2 SV=1)

HSP 1 Score: 117.472 bits (293), Expect = 1.094e-27
Identity = 69/234 (29.49%), Postives = 124/234 (52.99%), Query Frame = 1 
Query:  508 PKIVDFDKKIHSARVANDSLSMAKLLHDQQKLLKNSEFSPIKSMIYSLLQIPVFLSVMIGLKNMAELPVASLQTGGAFWFTDLTMYDPYYILPVSTMMLLFLQLEVGADVK-KNTNSGYLKWGIRSLPIVALAFTCRLPSALLLYWWTSSCMSLVFSGIMSIPFVKTRLGLSALSYQAPTATDSKLGYLQNFKES--NAEKRITKLAKQYHNLEHENWIKARTSSIPKTYKYDP 1200
            P+I  F  +I  A++  +     +   +     K  +    + +I  L Q P+F+S  I L+ MA LPV SLQTGG +WF DLT+ DP Y+LP+     ++  LE+GA+   ++++  +++  IR +P+  L  T   P+A+ +YW +S+  SL     + IP V+T L +       P     + G+L++FK+   NAE    +L ++   +++   + AR   + +T+ ++P
Sbjct:  174 PEIQKFSARIREAKLTGNHTEFYRASSEMTFYQKKHDIKLFRPLILPLTQAPIFISFFIALREMANLPVPSLQTGGLWWFQDLTLSDPIYVLPLVVTATMWGVLELGAETGMQSSDLQWMRNFIRLMPLAVLPITIHFPTAVFMYWLSSNMFSLGQVACLRIPAVRTVLKIPQRVVHDPDKLAPREGFLKSFKQGWKNAEM-AHQLQERERRMQNHLELAAR-GPLRQTFAHNP 405

HSP 2 Score: 54.299 bits (129), Expect = 1.191e-6
Identity = 23/40 (57.50%), Postives = 27/40 (67.50%), Query Frame = 3 
Query:  261 GEPTFKSLGLNSYWPSGWVQHLYEIMHVDLGLPWWSTIVA 380
             E +F  LGL SY P G +Q+L E MHV+LGLPWW  I A
Sbjct:  107 AEQSFAELGLGSYTPVGLIQNLLEFMHVNLGLPWWGAIAA 146
[Close]
BLAST of Membrane protein insertase YidC vs. UniProt/SwissProt
Match: sp|P39952|OXA1_YEAST (Mitochondrial inner membrane protein OXA1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=OXA1 PE=1 SV=1)

HSP 1 Score: 77.7962 bits (190), Expect = 3.627e-21
Identity = 63/229 (27.51%), Postives = 108/229 (47.16%), Query Frame = 1 
Query:  448 VMSPISYKIKQLTIINSYISPKIVDFDKKIHSARVANDSLSMAKLLHDQQKLLKNSEFSPIKSMIYSLLQIPVFLSVMIGLKNMAELPVASLQTGGAFWFTDLTMYDPYYILPVSTMMLLFLQLEVGADVKKNTNSGYLKWGIRSLPIVALAFTCRLPSALLLYWWTSSCMSLVFSGIMSIPFVKTRLGLSALSY-QAPTATDS---KLGYLQNFKES------NAEKR 1104
            +M P+  K       NS+I P++   + K+ S       L   +L+  Q+K L +S     + +   +LQIP+ L     L++MA  PV      G  WFTDLT  DPY  L V T  +      +G +      S  +K     LPI+++  T  L SA++LY+  +   S++ + I+   +V+++L ++ ++  + P A  S    +G  Q+ K +       AE+R
Sbjct:  142 LMFPLYVKSSDTVARNSHIKPELDALNNKLMST----TDLQQGQLVAMQRKKLLSSHGIKNRWLAAPMLQIPIALGFFNALRHMANYPVDGFANQGVAWFTDLTQADPYLGLQVITAAVFISFTRLGGETGAQQFSSPMKRLFTILPIISIPATMNLSSAVVLYFAFNGAFSVLQTMILRNKWVRSKLKITEVAKPRTPIAGASPTENMGIFQSLKHNIQKARDQAERR 366

HSP 2 Score: 46.2098 bits (108), Expect = 3.627e-21
Identity = 22/46 (47.83%), Postives = 29/46 (63.04%), Query Frame = 3 
Query:  252 NHLGEPTFKSLGLNS--YWPSGWVQHLYEIMHVDLGLPWWSTIVAS 383
            +H+G     S+GL    YWPS  +QH+ E +HV  GLPWW TI A+
Sbjct:   92 SHIGY--LNSIGLAQTWYWPSDIIQHVLEAVHVYSGLPWWGTIAAT 135
[Close]
BLAST of Membrane protein insertase YidC vs. UniProt/SwissProt
Match: sp|O43092|OXA12_SCHPO (Mitochondrial inner membrane protein oxa1-2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=oxa102 PE=2 SV=2)

HSP 1 Score: 87.8113 bits (216), Expect = 1.220e-19
Identity = 54/212 (25.47%), Postives = 101/212 (47.64%), Query Frame = 1 
Query:  457 PISYKIKQLTIINSYISPKIVDFDKKIHSARVANDSLSMAKLLHDQQKLLKNSEFSPIKSMIYSLLQIPVFLSVMIGLKNMAELPVASLQTGGAFWFTDLTMYDPYYILPVSTMMLLFLQLEVGADVKKN--TNSGYLKWGIRSLPIVALAFTCRLPSALLLYWWTSSCMSLVFSGIMSIPFVKTRLGLSALSYQAPTATDSKLGYLQNFKE 1086
            PI  K+ + +   + I+PK+ +    +  A+   +S  M +     Q L K +  +P+  +   + Q  +F+S    LK MA +PV     GG +W  DL+  DP +I PV+  +L+ L +E+G++   N    S  +K   R L + +  FT   P A+ +YW+ S+  S+     +    ++ +LGL  +    P        ++++F +
Sbjct:  132 PIMLKMMKTSAKLAIINPKVAEHMSVLSKAKAEGNSELMMQATTQIQNLYKVNNVNPLNLLSAPVFQGILFISFFYALKTMAGVPVEGFTDGGFWWVNDLSQPDPLHIFPVANGLLMLLNIELGSETGSNKVAMSPSMKKFFRFLCLASPLFTMNFPMAIFMYWFPSNVFSVFQGAFLRSSTIRHKLGLPEVPSAMPVPNAQNESFVKSFTD 343

HSP 2 Score: 31.187 bits (69), Expect = 1.220e-19
Identity = 14/43 (32.56%), Postives = 24/43 (55.81%), Query Frame = 3 
Query:  294 SYWPSGWVQHLYEIMHVDLGLPWWSTIVASRFPMGNIYIFKVL 422
            S+ P   +Q+    +H+  GLPWW++I A    M  I +F ++
Sbjct:   93 SFLPHNILQNGLNTLHIWSGLPWWASIAACAVAM-RIAVFPIM 134
[Close]
BLAST of Membrane protein insertase YidC vs. TrEMBL
Match: A0A0R3SU49 (Uncharacterized protein OS=Hymenolepis diminuta OX=6216 GN=HDID_LOCUS8995 PE=3 SV=1)

HSP 1 Score: 174.096 bits (440), Expect = 4.049e-56
Identity = 90/237 (37.97%), Postives = 135/237 (56.96%), Query Frame = 1 
Query:  502 ISPKIVDFDKKIHSARVANDSLSMAKLLHDQQKLLKNSEFSPIKSMIYSLLQIPVFLSVMIGLKNMAELPVASLQTGGAFWFTDLTMYDPYYILPVSTMMLLFLQLEVGADVKKNTNSGYLKWGIRSLPIVALAFTCRLPSALLLYWWTSSCMSLVFSGIMSIPFVKTRLGLSALSYQAPTATDSKLGYLQNFKESNAEKRITKLAKQYHNLEHENWIKARTSSIPKTYKYDPTKVN 1212
            + PKI     ++  AR+ +D + M ++  + Q ++KN++ +P  SM    +Q+P+FL+V  GL+ MA+LPVASLQTGG  WF DLT+ DPYYILP+ +M  +FL  E G DV   T +  ++  +R  P+V       +PSALL YW  S+ +S+  + I+    V+  L         P  T SK G++Q FKES    R+    +     + E+W KA   +IPKT+ +D TK N
Sbjct:  151 VMPKITSLQSRMTKARINSDYIEMMRISQEMQDMMKNNDVNPFNSMRLMFVQVPIFLAVFAGLRGMAQLPVASLQTGGLSWFLDLTVCDPYYILPIYSMTSIFLMFEFGVDVSTQTVTPGVRLAMRCFPVVGFLMIMHMPSALLWYWSLSNTISIGQALILRTKPVREYLKFPERIPPPPQET-SKQGFVQGFKESMTNSRLLAELEARERTDAESWQKAGAGAIPKTFAHDITKRN 386

HSP 2 Score: 75.0998 bits (183), Expect = 4.049e-56
Identity = 31/47 (65.96%), Postives = 36/47 (76.60%), Query Frame = 3 
Query:  249 LNHLGEPTFKSLGLNSYWPSGWVQHLYEIMHVDLGLPWWSTIVASRF 389
            LN LGEPTF SLGLNS+WPSGW Q L E +HV+  LPWW+ I A+ F
Sbjct:   82 LNALGEPTFASLGLNSWWPSGWYQALLETLHVNFDLPWWAAIAATTF 128
[Close]
BLAST of Membrane protein insertase YidC vs. TrEMBL
Match: A0A0R3WK94 (Uncharacterized protein OS=Hydatigena taeniaeformis OX=6205 GN=TTAC_LOCUS1130 PE=3 SV=2)

HSP 1 Score: 169.474 bits (428), Expect = 5.745e-55
Identity = 92/248 (37.10%), Postives = 140/248 (56.45%), Query Frame = 1 
Query:  460 ISYKIKQLTIINSY--ISPKIVDFDKKIHSARVANDSLSMAKLLHDQQKLLKNSEFSPIKSMIYSLLQIPVFLSVMIGLKNMAELPVASLQTGGAFWFTDLTMYDPYYILPVSTMMLLFLQLEVGADVKKNTNSGYLKWGIRSLPIVALAFTCRLPSALLLYWWTSSCMSLVFSGIMSIPFVKTRLGLSALSYQAPTATDSKLGYLQNFKESNAEKRITKLAKQYHNLEHENWIKARTSSIPKTYKYD 1197
            I + I Q   + SY  + P+I     ++  ARVA+D + M K+  + Q+L+KN++ + + SM  +L+Q+P+FLSV  GL+ MA+LPV SLQTGG  WF DLT+ DP+Y+LP+ +M  +FL  E GADV     +  ++  +R  P+V       +PSALL YW  S+ +S+  + I+    V+T L         P     K G+++ FKES    R+    +    ++ E W KA    IPKT+ YD
Sbjct:  126 IPFVINQRRKLASYTNVMPQIHALQNRMTRARVASDYIEMMKVSQEMQQLMKNNDVNLLNSMGLALIQVPIFLSVFAGLRGMAQLPVESLQTGGLGWFADLTVCDPFYVLPLYSMSSIFLMFEFGADVSSQGLTTGVRLAMRIFPVVGFFMIMHMPSALLWYWSISNTISISQALILRTKPVRTYLKFPE-KVNPPPQLGRKKGFVEGFKESMNNSRLLAELEARERMDAERWQKAGMGPIPKTFAYD 372

HSP 2 Score: 75.8702 bits (185), Expect = 5.745e-55
Identity = 31/47 (65.96%), Postives = 35/47 (74.47%), Query Frame = 3 
Query:  243 LDLNHLGEPTFKSLGLNSYWPSGWVQHLYEIMHVDLGLPWWSTIVAS 383
            + LN LGEPTF SLGLNSYWPSGW Q   E +HVDL LPWW+ I  +
Sbjct:   71 IPLNALGEPTFASLGLNSYWPSGWYQAALEFLHVDLNLPWWAAIATT 117
[Close]
BLAST of Membrane protein insertase YidC vs. TrEMBL
Match: A0A0R3UNU4 (Uncharacterized protein OS=Mesocestoides corti OX=53468 GN=MCOS_LOCUS9489 PE=3 SV=1)

HSP 1 Score: 167.548 bits (423), Expect = 1.305e-54
Identity = 90/247 (36.44%), Postives = 141/247 (57.09%), Query Frame = 1 
Query:  472 IKQLTIINSY--ISPKIVDFDKKIHSARVANDSLSMAKLLHDQQKLLKNSEFSPIKSMIYSLLQIPVFLSVMIGLKNMAELPVASLQTGGAFWFTDLTMYDPYYILPVSTMMLLFLQLEVGADVKKNTNSGYLKWGIRSLPIVALAFTCRLPSALLLYWWTSSCMSLVFSGIMSIPFVKTRLGLSALSYQAPTATDSKLGYLQNFKESNAEKRITKLAKQYHNLEHENWIKARTSSIPKTYKYDPTK 1206
            I Q   + SY  + PKIV    ++  AR+ ++ + M K+  + Q+L+KN++ +P+ S+   ++Q+P+FLSV  GL+ MA+LPV SL+TGG  WF DLT+ DP+YILP  +M  +FL  E GADV     +  ++  +R  PIV       +PSALL YW  S+ +S+  + I+    V+  L    L+ + P   + K G+   FKES +  R+    +     + E W KA  + +PKT+ +D TK
Sbjct:  138 IDQRRKLASYTNVMPKIVALQNRMTKARINSNYIEMMKVSQEMQELMKNNDVNPLNSLRLMVVQVPIFLSVFAGLRGMAQLPVDSLKTGGLGWFVDLTVCDPFYILPFYSMASIFLMFEFGADVSSQGLTPAVRVMMRGFPIVGFFMIMHMPSALLWYWSISNTISIAQALILKSKPVRDFLQFPELA-KPPPQVEKKKGFFAGFKESMSNSRLIAELEARERTDAERWQKAGLNKVPKTFAFDTTK 383

HSP 2 Score: 76.2554 bits (186), Expect = 1.305e-54
Identity = 31/45 (68.89%), Postives = 36/45 (80.00%), Query Frame = 3 
Query:  249 LNHLGEPTFKSLGLNSYWPSGWVQHLYEIMHVDLGLPWWSTIVAS 383
            LN LGEPTF SLGLNSYWPSGW Q L E++HV+L LPWW+ I  +
Sbjct:   81 LNALGEPTFASLGLNSYWPSGWYQSLLEVLHVNLDLPWWAAIATT 125
[Close]
BLAST of Membrane protein insertase YidC vs. TrEMBL
Match: U6J895 (Cytochrome oxidase biogenesis protein OS=Echinococcus granulosus OX=6210 GN=EGR_06639 PE=3 SV=1)

HSP 1 Score: 167.933 bits (424), Expect = 2.575e-54
Identity = 90/253 (35.57%), Postives = 142/253 (56.13%), Query Frame = 1 
Query:  460 ISYKIKQLTIINSY--ISPKIVDFDKKIHSARVANDSLSMAKLLHDQQKLLKNSEFSPIKSMIYSLLQIPVFLSVMIGLKNMAELPVASLQTGGAFWFTDLTMYDPYYILPVSTMMLLFLQLEVGADVKKNTNSGYLKWGIRSLPIVALAFTCRLPSALLLYWWTSSCMSLVFSGIMSIPFVKTRLGLSALSYQAPTATDSKLGYLQNFKESNAEKRITKLAKQYHNLEHENWIKARTSSIPKTYKYDPTKVN 1212
            I + I Q   + +Y  + P+I     ++  ARV +D + M K+  + Q L+KN++ +P+ SM   L+Q+P+FLSV  GL+ MA+LPV SLQTGG  WF DLT+ DP YILP+ +M  +FL  E GAD+     +  ++  +R  P+V       +PSALL YW  S+ +S++ +  +    V+T L       + P    ++ G+++ FKES +  R+    +     + E W KA   ++PKT+ YD T  N
Sbjct:  133 IPFVIDQRRKLAAYTNVMPQINSLQNRMTRARVTSDYVEMMKVSQELQHLMKNNDINPLNSMRLVLIQVPIFLSVFAGLRGMAQLPVESLQTGGLGWFADLTVCDPLYILPLYSMSSIFLMFEFGADMSSQGLTPGVRLAMRVFPVVGFFMIMHMPSALLWYWSISNTISILQALTLRTKSVRTYLKFPE-KVEPPPQLKNRKGFVEGFKESMSNSRLLAELEARERTDAERWQKAGMGAVPKTFAYDITTRN 384

HSP 2 Score: 75.0998 bits (183), Expect = 2.575e-54
Identity = 31/47 (65.96%), Postives = 36/47 (76.60%), Query Frame = 3 
Query:  243 LDLNHLGEPTFKSLGLNSYWPSGWVQHLYEIMHVDLGLPWWSTIVAS 383
            L LN LGEPTF SLGLNSYWPSGW Q + E +HV+L LPWW+ I  +
Sbjct:   78 LALNALGEPTFASLGLNSYWPSGWYQAVLEFLHVNLDLPWWAAIATT 124
[Close]
BLAST of Membrane protein insertase YidC vs. TrEMBL
Match: A0A087W281 (Cytochrome oxidase biolocus tagsis protein OS=Echinococcus multilocularis OX=6211 GN=EmuJ_000251800 PE=3 SV=1)

HSP 1 Score: 168.318 bits (425), Expect = 4.915e-54
Identity = 91/253 (35.97%), Postives = 142/253 (56.13%), Query Frame = 1 
Query:  460 ISYKIKQLTIINSY--ISPKIVDFDKKIHSARVANDSLSMAKLLHDQQKLLKNSEFSPIKSMIYSLLQIPVFLSVMIGLKNMAELPVASLQTGGAFWFTDLTMYDPYYILPVSTMMLLFLQLEVGADVKKNTNSGYLKWGIRSLPIVALAFTCRLPSALLLYWWTSSCMSLVFSGIMSIPFVKTRLGLSALSYQAPTATDSKLGYLQNFKESNAEKRITKLAKQYHNLEHENWIKARTSSIPKTYKYDPTKVN 1212
            I + I Q   + +Y  + P+I     ++  ARV +D + M K+  + Q L+KN++ +P+ SM   L+Q+P+FLSV  GL+ MA+LPV SLQTGG  WF DLT+ DP YILP+ +M  +FL  E GAD+     +  ++  +R  P+V       +PSALL YW  S+ +S+  + I+    V+T L       + P    ++ G+++ FKES +  R+    +     + E W KA   ++PKT+ YD T  N
Sbjct:  133 IPFVIDQRRKLAAYTNVMPQINSLQNRMTRARVTSDYVEMMKVSQELQHLMKNNDINPLNSMRLVLIQVPIFLSVFAGLRGMAQLPVESLQTGGLGWFADLTVCDPLYILPLYSMSSIFLMFEFGADMSSQGLTPGVRLAMRIFPVVGFFMIMHMPSALLWYWSISNTISISQALILRTKSVRTYLKFPE-KVEPPPQLKNRKGFVEGFKESMSNSRLLAELEARERTDAERWQKAGMGAVPKTFAYDITTRN 384

HSP 2 Score: 73.559 bits (179), Expect = 4.915e-54
Identity = 30/45 (66.67%), Postives = 35/45 (77.78%), Query Frame = 3 
Query:  249 LNHLGEPTFKSLGLNSYWPSGWVQHLYEIMHVDLGLPWWSTIVAS 383
            LN LGEPTF SLGLNSYWPSGW Q + E +HV+L LPWW+ I  +
Sbjct:   80 LNALGEPTFASLGLNSYWPSGWYQAVLEFLHVNLDLPWWAAIATT 124
[Close]
BLAST of Membrane protein insertase YidC vs. Ensembl Cavefish
Match: oxa1l (OXA1L mitochondrial inner membrane protein [Source:ZFIN;Acc:ZDB-GENE-071004-49])

HSP 1 Score: 125.176 bits (313), Expect = 2.295e-31
Identity = 75/239 (31.38%), Postives = 124/239 (51.88%), Query Frame = 1 
Query:  508 PKIVDFDKKIHSARVANDSLSMAKLLHDQQKLLKNSEFSPIKSMIYSLLQIPVFLSVMIGLKNMAELPVASLQTGGAFWFTDLTMYDPYYILPVSTMMLLFLQLEVGADVK-KNTNSGYLKWGIRSLPIVALAFTCRLPSALLLYWWTSSCMSLVFSGIMSIPFVKTRLGLSALSYQAPTATDSKLGYLQNFKES--NAEKRITKLAKQYHNLEHENWIK-----ARTSSIPKTYKYDP 1200
            P++     +++ A+ + +    +K   +     K  + +P++  +  L+Q PVF+S  I L+ MA LPV SLQTGG  WFTDLT  DPY+ILP +    +F  +E+GA+    N N   +K   R +P+V L  T   P+A+ +YW TS+  SL    ++  P V+ +L +       P+A     G++++ K+   NA+     LA+Q    E E  IK     A    + +T+ ++P
Sbjct:  183 PEMTKISNRMNEAKHSGNKFEFSKAYSELMMFYKKHDVNPVRGFLVPLVQAPVFISFFIALRQMAYLPVPSLQTGGLGWFTDLTAADPYFILPFAVTGTMFAIVELGAESGLDNPNLRAMKTVFRIMPLVILPMTINFPTAVFVYWLTSNVFSLGQVALLRHPAVRKKLRIPERKTHPPSALPPNEGFIKSIKKGIHNAQ-----LAQQLE--EREKRIKGHLDMASKGPLRQTFAHNP 414

HSP 2 Score: 50.447 bits (119), Expect = 1.933e-6
Identity = 21/41 (51.22%), Postives = 27/41 (65.85%), Query Frame = 3 
Query:  261 GEPTFKSLGLNSYWPSGWVQHLYEIMHVDLGLPWWSTIVAS 383
             E +   LGL +Y P G +Q+L E MHV++GLPWW  IVA 
Sbjct:  116 AELSLTDLGLGNYTPVGLIQNLLEFMHVNIGLPWWCAIVAG 156
[Close]
BLAST of Membrane protein insertase YidC vs. Ensembl Cavefish
Match: oxa1l (OXA1L mitochondrial inner membrane protein [Source:ZFIN;Acc:ZDB-GENE-071004-49])

HSP 1 Score: 124.79 bits (312), Expect = 6.442e-31
Identity = 75/239 (31.38%), Postives = 124/239 (51.88%), Query Frame = 1 
Query:  508 PKIVDFDKKIHSARVANDSLSMAKLLHDQQKLLKNSEFSPIKSMIYSLLQIPVFLSVMIGLKNMAELPVASLQTGGAFWFTDLTMYDPYYILPVSTMMLLFLQLEVGADVK-KNTNSGYLKWGIRSLPIVALAFTCRLPSALLLYWWTSSCMSLVFSGIMSIPFVKTRLGLSALSYQAPTATDSKLGYLQNFKES--NAEKRITKLAKQYHNLEHENWIK-----ARTSSIPKTYKYDP 1200
            P++     +++ A+ + +    +K   +     K  + +P++  +  L+Q PVF+S  I L+ MA LPV SLQTGG  WFTDLT  DPY+ILP +    +F  +E+GA+    N N   +K   R +P+V L  T   P+A+ +YW TS+  SL    ++  P V+ +L +       P+A     G++++ K+   NA+     LA+Q    E E  IK     A    + +T+ ++P
Sbjct:  241 PEMTKISNRMNEAKHSGNKFEFSKAYSELMMFYKKHDVNPVRGFLVPLVQAPVFISFFIALRQMAYLPVPSLQTGGLGWFTDLTAADPYFILPFAVTGTMFAIVELGAESGLDNPNLRAMKTVFRIMPLVILPMTINFPTAVFVYWLTSNVFSLGQVALLRHPAVRKKLRIPERKTHPPSALPPNEGFIKSIKKGIHNAQ-----LAQQLE--EREKRIKGHLDMASKGPLRQTFAHNP 472

HSP 2 Score: 50.447 bits (119), Expect = 2.686e-6
Identity = 21/41 (51.22%), Postives = 27/41 (65.85%), Query Frame = 3 
Query:  261 GEPTFKSLGLNSYWPSGWVQHLYEIMHVDLGLPWWSTIVAS 383
             E +   LGL +Y P G +Q+L E MHV++GLPWW  IVA 
Sbjct:  174 AELSLTDLGLGNYTPVGLIQNLLEFMHVNIGLPWWCAIVAG 214
[Close]
BLAST of Membrane protein insertase YidC vs. Ensembl Cavefish
Match: cox18 (mitochondrial inner membrane protein COX18 [Source:NCBI gene;Acc:103035388])

HSP 1 Score: 65.0846 bits (157), Expect = 2.989e-11
Identity = 45/157 (28.66%), Postives = 84/157 (53.50%), Query Frame = 1 
Query:  625 PIKSMIYSLLQIPVFLSVMIGLKNMA---ELPVASLQ----TGGAFWFTDLTMYDPYYILPVSTMMLLFLQLEVGADVKKNTN--SGYLKWGIRSLPIVALAFTCRLPSALLLYWWTSSCMSLVFSGIMSIPFVKTRLGLSALSYQAPTATDSKLGY 1068
            P K+ +   +Q+P+++ + + L+N++       A LQ     GGA WF++LT+ D  +I+PVS  ++  L  E+ A  + + +    Y+   IR + +V +  +  +PS++ LYW +SSC+ L  + ++  P  +T      L    PT +DS+  Y
Sbjct:  196 PFKASLLIWVQLPMWVCLSLALRNLSMGIGHASAGLQQELAAGGALWFSNLTLPDSTWIIPVSLGLINLLITEIFAVTRLDASRFQRYVTHFIRGISLVMIPLSAAVPSSMALYWLSSSCVGLGHNLLLRSPRFRT------LCRIPPTRSDSETPY 346
[Close]
BLAST of Membrane protein insertase YidC vs. Ensembl Yeast
Match: OXA1 (Mitochondrial inner membrane insertase; mediates the insertion of both mitochondrial- and nuclear-encoded proteins from the matrix into the inner membrane; also has a role in insertion of carrier proteins into the inner membrane; acts as a voltage-gated ion channel, activated by substrate peptides; interacts with mitochondrial ribosomes; conserved from bacteria to animals [Source:SGD;Acc:S000000956])

HSP 1 Score: 77.7962 bits (190), Expect = 6.815e-23
Identity = 63/229 (27.51%), Postives = 108/229 (47.16%), Query Frame = 1 
Query:  448 VMSPISYKIKQLTIINSYISPKIVDFDKKIHSARVANDSLSMAKLLHDQQKLLKNSEFSPIKSMIYSLLQIPVFLSVMIGLKNMAELPVASLQTGGAFWFTDLTMYDPYYILPVSTMMLLFLQLEVGADVKKNTNSGYLKWGIRSLPIVALAFTCRLPSALLLYWWTSSCMSLVFSGIMSIPFVKTRLGLSALSY-QAPTATDS---KLGYLQNFKES------NAEKR 1104
            +M P+  K       NS+I P++   + K+ S       L   +L+  Q+K L +S     + +   +LQIP+ L     L++MA  PV      G  WFTDLT  DPY  L V T  +      +G +      S  +K     LPI+++  T  L SA++LY+  +   S++ + I+   +V+++L ++ ++  + P A  S    +G  Q+ K +       AE+R
Sbjct:  142 LMFPLYVKSSDTVARNSHIKPELDALNNKLMST----TDLQQGQLVAMQRKKLLSSHGIKNRWLAAPMLQIPIALGFFNALRHMANYPVDGFANQGVAWFTDLTQADPYLGLQVITAAVFISFTRLGGETGAQQFSSPMKRLFTILPIISIPATMNLSSAVVLYFAFNGAFSVLQTMILRNKWVRSKLKITEVAKPRTPIAGASPTENMGIFQSLKHNIQKARDQAERR 366

HSP 2 Score: 46.2098 bits (108), Expect = 6.815e-23
Identity = 22/46 (47.83%), Postives = 29/46 (63.04%), Query Frame = 3 
Query:  252 NHLGEPTFKSLGLNS--YWPSGWVQHLYEIMHVDLGLPWWSTIVAS 383
            +H+G     S+GL    YWPS  +QH+ E +HV  GLPWW TI A+
Sbjct:   92 SHIGY--LNSIGLAQTWYWPSDIIQHVLEAVHVYSGLPWWGTIAAT 135
[Close]
BLAST of Membrane protein insertase YidC vs. Ensembl Nematostella
Match: EDO47264 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RMF7])

HSP 1 Score: 124.02 bits (310), Expect = 2.812e-38
Identity = 62/234 (26.50%), Postives = 121/234 (51.71%), Query Frame = 1 
Query:  502 ISPKIVDFDKKIHSARVANDSLSMAKLLHDQQKLLKNSEFSPIKSMIYSLLQIPVFLSVMIGLKNMAELPVASLQTGGAFWFTDLTMYDPYYILPVSTMMLLFLQLEVGADVK-KNTNSGYLKWGIRSLPIVALAFTCRLPSALLLYWWTSSCMSLVFSGIMSIPFVKTRLGLSALSYQAPTATDSKLGYLQNFKESNAEKRITKLAKQYHNLEHENWIKARTSSIPKTYKYDP 1200
            + P++ +   ++     +N+++  A      Q+L K+++  PIKS+I  L+Q+P+F+S  +GL+ MA LPV S + GG FWFTDLT YDPY++LP+   + +   +E+G +    N    ++K   R + +  +  T + P+A+  YW TS+  SL    ++ +  V+   G+  +         ++ G+ +N        +     K +  ++ +      T+ +  TY+++P
Sbjct:   73 VKPELEEVQAQLRDLMNSNNAIGKAAASARLQQLYKDNDCHPIKSIIAPLVQVPLFISFFVGLRRMANLPVESFKEGGLFWFTDLTAYDPYFVLPIVCSLTMLASIELGGEAGVSNPQMQHMKTFFRVMCVAMIPLTAQFPAAIFTYWVTSNLFSLGQVSLLKVKAVREYFGIPEMKVH--KNLPAQGGFWENMSAGYKNAKEEAYVKHHEKMKRQKEKALGTAPLETTYEHNP 304

HSP 2 Score: 52.7582 bits (125), Expect = 2.812e-38
Identity = 22/46 (47.83%), Postives = 30/46 (65.22%), Query Frame = 3 
Query:  249 LNHLGEPTFKSLGLNSYWPSGWVQHLYEIMHVDLGLPW-WSTIVAS 383
            +N +GEPT  S+GL    P G VQH  E++H  +GLPW WS + A+
Sbjct:    4 VNAIGEPTLASMGLGGTTPIGLVQHALEMLHATVGLPWVWSIVAAT 49
[Close]
BLAST of Membrane protein insertase YidC vs. Ensembl Nematostella
Match: EDO32922 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7STR0])

HSP 1 Score: 52.373 bits (124), Expect = 9.119e-8
Identity = 36/171 (21.05%), Postives = 85/171 (49.71%), Query Frame = 1 
Query:  598 KLLKNSEFSPIKSMIYSLLQIPVFLSVMIGLKNMA--------ELPVASLQTGGAFWFTDLTMYDPYYILPVSTMMLLFLQLEVGADVKKNTNSGYLKW---GIRSLPIVALAFTCRLPSALLLYWWTSSCMSLVFSGIMSIPFVKTRLGLSALSYQAPTATDSKLGYLQN 1077
            +L +    +PIK  +   +Q+P+++ + + L++M          +    + + GA WF DL + DP  ++P++  +     +E+ A +++   S + +     +R L +  + F  ++P+A+ LYW  S+   +  +  + +P V+ +LG+     + P+ + +    L+N
Sbjct:   96 ELYQGEGCNPIKMFLLPWIQLPLWILISLSLRSMTGTSYSQRNSVLCPEMASEGALWFPDLLVPDPTIMIPLAVGICNLTNIEMHA-LRRQQPSRFQRVMTNTLRLLSVFMVMFASQVPTAMSLYWAVSAGFGVCQNVCLKLPTVRRQLGIP----KTPSESKTPFRDLRN 261
[Close]
BLAST of Membrane protein insertase YidC vs. Ensembl Medaka
Match: oxa1l (OXA1L mitochondrial inner membrane protein [Source:NCBI gene;Acc:101170220])

HSP 1 Score: 123.635 bits (309), Expect = 8.539e-37
Identity = 76/239 (31.80%), Postives = 122/239 (51.05%), Query Frame = 1 
Query:  508 PKIVDFDKKIHSARVANDSLSMAKLLHDQQKLLKNSEFSPIKSMIYSLLQIPVFLSVMIGLKNMAELPVASLQTGGAFWFTDLTMYDPYYILPVSTMMLLFLQLEVGADVK-KNTNSGYLKWGIRSLPIVALAFTCRLPSALLLYWWTSSCMSLVFSGIMSIPFVKTRLGLSALSYQAPTATDSKLGYLQNFKES--NAEKRITKLAKQYHNLEHENWIK-----ARTSSIPKTYKYDP 1200
            P+I     +++ A+ + +    AK   D     K ++ +P++  +  L+Q PVF+S  I L+ MA LPV SLQTGG  WFTDLT  DP+YILP++    +F  LE+GA+    N N   +K   R +P+V L  T   P+A+  YW +S+  SL    ++  P V+ +  +        +A     G +++ K+   NA+     LA+Q    E E  IK     A    + +T+ ++P
Sbjct:  251 PEITKLTNRMNEAKQSGNKFEFAKAYSDLNLFQKKNDVNPLRGFLVPLVQAPVFISFFIALRKMAYLPVPSLQTGGMLWFTDLTAADPFYILPIAVTGTMFFILELGAESGIDNPNLRAMKTVFRIMPLVILPLTINFPTAVFTYWLSSNLFSLGQVALLRHPAVRKKFKIPEKIQHPASALPQNNGLIESMKKGWKNAQ-----LAQQLE--ERERRIKNHLDLAAKGPLRQTFSHNP 482

HSP 2 Score: 50.0618 bits (118), Expect = 8.539e-37
Identity = 22/54 (40.74%), Postives = 29/54 (53.70%), Query Frame = 3 
Query:  261 GEPTFKSLGLNSYWPSGWVQHLYEIMHVDLGLPWWSTIVASRFPMGNIYIFKVL 422
             EP    LGL    P G +Q+L E  H+DLGLPWW  IV     +  + +F V+
Sbjct:  184 AEPRLAELGLAGNTPVGLIQNLLEFFHMDLGLPWWGAIVVGTV-LARLAVFPVI 236
[Close]
BLAST of Membrane protein insertase YidC vs. Ensembl Medaka
Match: oxa1l (OXA1L mitochondrial inner membrane protein [Source:NCBI gene;Acc:101170220])

HSP 1 Score: 123.25 bits (308), Expect = 8.982e-37
Identity = 76/239 (31.80%), Postives = 122/239 (51.05%), Query Frame = 1 
Query:  508 PKIVDFDKKIHSARVANDSLSMAKLLHDQQKLLKNSEFSPIKSMIYSLLQIPVFLSVMIGLKNMAELPVASLQTGGAFWFTDLTMYDPYYILPVSTMMLLFLQLEVGADVK-KNTNSGYLKWGIRSLPIVALAFTCRLPSALLLYWWTSSCMSLVFSGIMSIPFVKTRLGLSALSYQAPTATDSKLGYLQNFKES--NAEKRITKLAKQYHNLEHENWIK-----ARTSSIPKTYKYDP 1200
            P+I     +++ A+ + +    AK   D     K ++ +P++  +  L+Q PVF+S  I L+ MA LPV SLQTGG  WFTDLT  DP+YILP++    +F  LE+GA+    N N   +K   R +P+V L  T   P+A+  YW +S+  SL    ++  P V+ +  +        +A     G +++ K+   NA+     LA+Q    E E  IK     A    + +T+ ++P
Sbjct:  211 PEITKLTNRMNEAKQSGNKFEFAKAYSDLNLFQKKNDVNPLRGFLVPLVQAPVFISFFIALRKMAYLPVPSLQTGGMLWFTDLTAADPFYILPIAVTGTMFFILELGAESGIDNPNLRAMKTVFRIMPLVILPLTINFPTAVFTYWLSSNLFSLGQVALLRHPAVRKKFKIPEKIQHPASALPQNNGLIESMKKGWKNAQ-----LAQQLE--ERERRIKNHLDLAAKGPLRQTFSHNP 442

HSP 2 Score: 50.447 bits (119), Expect = 8.982e-37
Identity = 22/54 (40.74%), Postives = 29/54 (53.70%), Query Frame = 3 
Query:  261 GEPTFKSLGLNSYWPSGWVQHLYEIMHVDLGLPWWSTIVASRFPMGNIYIFKVL 422
             EP    LGL    P G +Q+L E  H+DLGLPWW  IV     +  + +F V+
Sbjct:  144 AEPRLAELGLAGNTPVGLIQNLLEFFHMDLGLPWWGAIVVGTV-LARLAVFPVI 196
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BLAST of Membrane protein insertase YidC vs. Ensembl Medaka
Match: cox18 (mitochondrial inner membrane protein COX18 [Source:NCBI gene;Acc:101166537])

HSP 1 Score: 62.003 bits (149), Expect = 3.547e-10
Identity = 50/163 (30.67%), Postives = 85/163 (52.15%), Query Frame = 1 
Query:  625 PIKSMIYSLLQIPVFLSVMIGLKNMAELPVASLQ----TGGAFWFTDLTMYDPYYILPVSTMMLLFLQLEVGADVKKNTNSGYLKW---GIRSLPIVALAFTCRLPSALLLYWWTSSCMSLVFSGIMSIPFVKTRLGLSALSYQAP-----TATDSKLGYLQN 1077
            P K+ +   +Q+P+++S+ + L+N++ L  ++LQ     GGA WF+DLT+ D  +ILPV   +   L +EV   +++   SG  +    GIR   ++ +     +PS++ LYW+TSS +    + I+  P V   L L     + P     +A  SK G  Q 
Sbjct:  174 PFKASLLVWVQLPLWISLSLALRNLS-LNQSALQEELAAGGALWFSDLTVPDSTWILPVCLGLTNLLIVEV-FSLQRVGVSGVQRLVLNGIRGFCVLMIPIAAVVPSSMALYWFTSSLVGFSHNLILRSPAVHKILRLPTRRSETPYRDLLSAFISKCGLKQT 334
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BLAST of Membrane protein insertase YidC vs. Planmine SMEST
Match: SMESG000039158.1 (SMESG000039158.1)

HSP 1 Score: 527.324 bits (1357), Expect = 0.000e+0
Identity = 258/261 (98.85%), Postives = 259/261 (99.23%), Query Frame = 1 
Query:  445 MVMSPISYKIKQLTIINSYISPKIVDFDKKIHSARVANDSLSMAKLLHDQQKLLKNSEFSPIKSMIYSLLQIPVFLSVMIGLKNMAELPVASLQTGGAFWFTDLTMYDPYYILPVSTMMLLFLQLEVGADVKKNTNSGYLKWGIRSLPIVALAFTCRLPSALLLYWWTSSCMSLVFSGIMSIPFVKTRLGLSALSYQAPTATDSKLGYLQNFKESNAEKRITKLAKQYHNLEHENWIKARTSSIPKTYKYDPTKVNPTQFN 1227
            MVMSPISYKIKQLTIINSYISPKI DFDKKIHSARVANDSLSMAKLLHDQQKLLKNSEFSPIKSMIYSLLQIPVFLSVMIGLKNMAELPVASLQTGGAFWFTDLTMYDPYYILPVSTMMLLFLQLEVGADVKKNTNSGYLKWGIRSLPIVALAFTCRLPSALLLYWWTSSCMSLVFSGIMSIPFVKTR+GLSALSYQAPTATDSKLGYLQNFKESNAEKRITKLAKQYHNLEHENWIKA TSSIPKTYKYDPTKVNPTQFN
Sbjct:  124 MVMSPISYKIKQLTIINSYISPKIADFDKKIHSARVANDSLSMAKLLHDQQKLLKNSEFSPIKSMIYSLLQIPVFLSVMIGLKNMAELPVASLQTGGAFWFTDLTMYDPYYILPVSTMMLLFLQLEVGADVKKNTNSGYLKWGIRSLPIVALAFTCRLPSALLLYWWTSSCMSLVFSGIMSIPFVKTRVGLSALSYQAPTATDSKLGYLQNFKESNAEKRITKLAKQYHNLEHENWIKAGTSSIPKTYKYDPTKVNPTQFN 384

HSP 2 Score: 216.468 bits (550), Expect = 0.000e+0
Identity = 118/118 (100.00%), Postives = 118/118 (100.00%), Query Frame = 3 
Query:   30 MLNMLISKFRPATLSQNYFSSIHNVYILNRKLSDISNDKIKVSEMTTEMNADVSKYYXXXXXXXXXXXXKFLDLNHLGEPTFKSLGLNSYWPSGWVQHLYEIMHVDLGLPWWSTIVAS 383
            MLNMLISKFRPATLSQNYFSSIHNVYILNRKLSDISNDKIKVSEMTTEMNADVSKYYLPEPPMDPELLPKFLDLNHLGEPTFKSLGLNSYWPSGWVQHLYEIMHVDLGLPWWSTIVAS
Sbjct:    1 MLNMLISKFRPATLSQNYFSSIHNVYILNRKLSDISNDKIKVSEMTTEMNADVSKYYLPEPPMDPELLPKFLDLNHLGEPTFKSLGLNSYWPSGWVQHLYEIMHVDLGLPWWSTIVAS 118
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BLAST of Membrane protein insertase YidC vs. Planmine SMEST
Match: SMESG000039158.1 (SMESG000039158.1)

HSP 1 Score: 527.324 bits (1357), Expect = 0.000e+0
Identity = 258/261 (98.85%), Postives = 259/261 (99.23%), Query Frame = 1 
Query:  445 MVMSPISYKIKQLTIINSYISPKIVDFDKKIHSARVANDSLSMAKLLHDQQKLLKNSEFSPIKSMIYSLLQIPVFLSVMIGLKNMAELPVASLQTGGAFWFTDLTMYDPYYILPVSTMMLLFLQLEVGADVKKNTNSGYLKWGIRSLPIVALAFTCRLPSALLLYWWTSSCMSLVFSGIMSIPFVKTRLGLSALSYQAPTATDSKLGYLQNFKESNAEKRITKLAKQYHNLEHENWIKARTSSIPKTYKYDPTKVNPTQFN 1227
            MVMSPISYKIKQLTIINSYISPKI DFDKKIHSARVANDSLSMAKLLHDQQKLLKNSEFSPIKSMIYSLLQIPVFLSVMIGLKNMAELPVASLQTGGAFWFTDLTMYDPYYILPVSTMMLLFLQLEVGADVKKNTNSGYLKWGIRSLPIVALAFTCRLPSALLLYWWTSSCMSLVFSGIMSIPFVKTR+GLSALSYQAPTATDSKLGYLQNFKESNAEKRITKLAKQYHNLEHENWIKA TSSIPKTYKYDPTKVNPTQFN
Sbjct:  121 MVMSPISYKIKQLTIINSYISPKIADFDKKIHSARVANDSLSMAKLLHDQQKLLKNSEFSPIKSMIYSLLQIPVFLSVMIGLKNMAELPVASLQTGGAFWFTDLTMYDPYYILPVSTMMLLFLQLEVGADVKKNTNSGYLKWGIRSLPIVALAFTCRLPSALLLYWWTSSCMSLVFSGIMSIPFVKTRVGLSALSYQAPTATDSKLGYLQNFKESNAEKRITKLAKQYHNLEHENWIKAGTSSIPKTYKYDPTKVNPTQFN 381

HSP 2 Score: 211.075 bits (536), Expect = 0.000e+0
Identity = 115/115 (100.00%), Postives = 115/115 (100.00%), Query Frame = 3 
Query:   39 MLISKFRPATLSQNYFSSIHNVYILNRKLSDISNDKIKVSEMTTEMNADVSKYYXXXXXXXXXXXXKFLDLNHLGEPTFKSLGLNSYWPSGWVQHLYEIMHVDLGLPWWSTIVAS 383
            MLISKFRPATLSQNYFSSIHNVYILNRKLSDISNDKIKVSEMTTEMNADVSKYYLPEPPMDPELLPKFLDLNHLGEPTFKSLGLNSYWPSGWVQHLYEIMHVDLGLPWWSTIVAS
Sbjct:    1 MLISKFRPATLSQNYFSSIHNVYILNRKLSDISNDKIKVSEMTTEMNADVSKYYLPEPPMDPELLPKFLDLNHLGEPTFKSLGLNSYWPSGWVQHLYEIMHVDLGLPWWSTIVAS 115
[Close]
BLAST of Membrane protein insertase YidC vs. Planmine SMEST
Match: SMESG000037475.1 (SMESG000037475.1)

HSP 1 Score: 105.145 bits (261), Expect = 1.820e-30
Identity = 73/200 (36.50%), Postives = 104/200 (52.00%), Query Frame = 1 
Query:  460 ISYKIKQLTIINSYISPKIVDFDKKIHSARVANDSLSMAKLLHDQQKLLKNSEFSPIKSMIYSLLQIPVFLSVMIGLKNMAELPVASLQTGGAFWFTDLTMYDPYYILPVSTMMLLFLQLEVGADVKKNTNSGYLKWGIRSLPIVALAFTCRLPSALLLYWWTSSCMSLVFSGIMSIPFVKTRLGLSALSYQAPTATDSK 1059
            IS +   + I NSY   K+     +   AR   +S  M + L + +K+   S F+  K +   L+Q PVF+SV   L+ M    + SL  GG +WF DLT+ DPY+ILP  T   L+L +E   ++   TNS   KW  R L  V+  F C++PS L+LYW  S+  SLVF+  +  P VK  L +  L   AP   + K
Sbjct:  122 ISQRRTTVNIQNSY--GKLTQLTIEATEAREMGNSFLMLQKLQEIEKISSESHFNFFKILQPLLIQAPVFISVFTALRGMTNAGIPSLAIGGLWWFPDLTVSDPYFILPAVTAGFLWLIIE--CNLTTTTNS---KWIFRGLGPVSFLFFCQMPSTLVLYWSISNLYSLVFALFLMNPKVKKFLKIPEL-VPAPIMDNPK 313

HSP 2 Score: 46.595 bits (109), Expect = 1.820e-30
Identity = 19/39 (48.72%), Postives = 27/39 (69.23%), Query Frame = 3 
Query:  267 PTFKSLGLNSYWPSGWVQHLYEIMHVDLGLPWWSTIVAS 383
            P+F SLGLN+  P+G+VQ + E +H  L LPWW+ I  +
Sbjct:   71 PSFSSLGLNNLTPTGFVQFILENVHNSLALPWWACIAIT 109
[Close]
BLAST of Membrane protein insertase YidC vs. Planmine SMEST
Match: SMESG000005570.1 (SMESG000005570.1)

HSP 1 Score: 74.3294 bits (181), Expect = 3.365e-15
Identity = 48/198 (24.24%), Postives = 100/198 (50.51%), Query Frame = 1 
Query:  469 KIKQLTIINSYISPKIVDFDKKIHSARVANDSLSMAKLLHDQQKLLKNSEFSPIKSMIYSLLQIPVFLSVMIGLK---NMAELPVASLQTGGAFWFTDLTMYDPYYILPVSTMMLLFLQLEVGADVKKNTN--SGYLKWGIRSLPIVALAFTCRLPSALLLYWWTSSCMSLVFSGIMSIPFVKTRLGL--SALSYQAP 1041
            K ++LT++N++     ++F KK+              +   +Q++    ++ P+K M+ S+ Q P +++    L+   N   L  A    GG  WF+D+T+ D Y+I+P+ T++  ++  E+    +          ++G R + ++   F+  +P++L +YW TSS   L+ + I+  P ++   G+  S+L Y+ P
Sbjct:   12 KAEELTMLNNWSHEAKINFIKKM--------------MKESRQEMFIEHQYHPLKPMVISMSQFPFWITTSFTLRVLYNKYHLSEA-FTNGGCLWFSDITIPDQYFIIPLITLVCSYINGEINYLKQPEIFFIHKVFRYGFRVISLMMFIFSSYMPTSLTIYWSTSSAFHLLCNIIIMNPKIRRFFGISKSSLEYETP 194
[Close]
BLAST of Membrane protein insertase YidC vs. Planmine SMEST
Match: SMESG000005570.1 (SMESG000005570.1)

HSP 1 Score: 73.559 bits (179), Expect = 1.713e-14
Identity = 48/198 (24.24%), Postives = 100/198 (50.51%), Query Frame = 1 
Query:  469 KIKQLTIINSYISPKIVDFDKKIHSARVANDSLSMAKLLHDQQKLLKNSEFSPIKSMIYSLLQIPVFLSVMIGLK---NMAELPVASLQTGGAFWFTDLTMYDPYYILPVSTMMLLFLQLEVGADVKKNTN--SGYLKWGIRSLPIVALAFTCRLPSALLLYWWTSSCMSLVFSGIMSIPFVKTRLGL--SALSYQAP 1041
            K ++LT++N++     ++F KK+              +   +Q++    ++ P+K M+ S+ Q P +++    L+   N   L  A    GG  WF+D+T+ D Y+I+P+ T++  ++  E+    +          ++G R + ++   F+  +P++L +YW TSS   L+ + I+  P ++   G+  S+L Y+ P
Sbjct:   63 KAEELTMLNNWSHEAKINFIKKM--------------MKESRQEMFIEHQYHPLKPMVISMSQFPFWITTSFTLRVLYNKYHLSEA-FTNGGCLWFSDITIPDQYFIIPLITLVCSYINGEINYLKQPEIFFIHKVFRYGFRVISLMMFIFSSYMPTSLTIYWSTSSAFHLLCNIIIMNPKIRRFFGISKSSLEYETP 245
The following BLAST results are available for this feature:
BLAST of Membrane protein insertase YidC vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
OXA1L2.137e-3031.49OXA1L mitochondrial inner membrane protein [Source... [more]
OXA1L2.620e-3031.49OXA1L mitochondrial inner membrane protein [Source... [more]
OXA1L7.427e-3031.49OXA1L mitochondrial inner membrane protein [Source... [more]
OXA1L4.318e-2933.82OXA1L mitochondrial inner membrane protein [Source... [more]
COX183.249e-925.60cytochrome c oxidase assembly factor COX18 [Source... [more]
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BLAST of Membrane protein insertase YidC vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1
Match NameE-valueIdentityDescription
oxa-17.557e-1424.00OXA mitochondrial inner membrane insertase homolog... [more]
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BLAST of Membrane protein insertase YidC vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 3
Match NameE-valueIdentityDescription
OXA1L6.844e-4535.17gene:FBgn0027615 transcript:FBtr0076271[more]
OXA1L6.844e-4535.17gene:FBgn0027615 transcript:FBtr0076272[more]
CG49429.797e-1027.10gene:FBgn0035960 transcript:FBtr0076524[more]
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BLAST of Membrane protein insertase YidC vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 3
Match NameE-valueIdentityDescription
oxa1l7.477e-3631.12OXA1L mitochondrial inner membrane protein [Source... [more]
oxa1l7.477e-3631.12OXA1L mitochondrial inner membrane protein [Source... [more]
cox181.255e-1126.19cytochrome c oxidase assembly factor COX18 [Source... [more]
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BLAST of Membrane protein insertase YidC vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 3
Match NameE-valueIdentityDescription
mpp21.089e-3427.31membrane protein, palmitoylated 2 [Source:Xenbase;... [more]
mpp25.729e-3330.77membrane protein, palmitoylated 2 [Source:Xenbase;... [more]
cox189.249e-1031.88cytochrome c oxidase assembly factor COX18 [Source... [more]
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BLAST of Membrane protein insertase YidC vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 4
Match NameE-valueIdentityDescription
Oxa1l1.729e-3330.60oxidase assembly 1-like [Source:MGI Symbol;Acc:MGI... [more]
Cox186.339e-1227.14cytochrome c oxidase assembly protein 18 [Source:M... [more]
Cox187.963e-1227.01cytochrome c oxidase assembly protein 18 [Source:M... [more]
Oxa1l1.359e-732.26oxidase assembly 1-like [Source:MGI Symbol;Acc:MGI... [more]
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BLAST of Membrane protein insertase YidC vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q8BGA9|OXA1L_MOUSE1.210e-3230.60Mitochondrial inner membrane protein OXA1L OS=Mus ... [more]
sp|Q15070|OXA1L_HUMAN1.309e-2931.49Mitochondrial inner membrane protein OXA1L OS=Homo... [more]
sp|Q3SYV3|OXA1L_BOVIN1.094e-2729.49Mitochondrial inner membrane protein OXA1L OS=Bos ... [more]
sp|P39952|OXA1_YEAST3.627e-2127.51Mitochondrial inner membrane protein OXA1 OS=Sacch... [more]
sp|O43092|OXA12_SCHPO1.220e-1925.47Mitochondrial inner membrane protein oxa1-2 OS=Sch... [more]
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BLAST of Membrane protein insertase YidC vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0R3SU494.049e-5637.97Uncharacterized protein OS=Hymenolepis diminuta OX... [more]
A0A0R3WK945.745e-5537.10Uncharacterized protein OS=Hydatigena taeniaeformi... [more]
A0A0R3UNU41.305e-5436.44Uncharacterized protein OS=Mesocestoides corti OX=... [more]
U6J8952.575e-5435.57Cytochrome oxidase biogenesis protein OS=Echinococ... [more]
A0A087W2814.915e-5435.97Cytochrome oxidase biolocus tagsis protein OS=Echi... [more]
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BLAST of Membrane protein insertase YidC vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 3
Match NameE-valueIdentityDescription
oxa1l2.295e-3131.38OXA1L mitochondrial inner membrane protein [Source... [more]
oxa1l6.442e-3131.38OXA1L mitochondrial inner membrane protein [Source... [more]
cox182.989e-1128.66mitochondrial inner membrane protein COX18 [Source... [more]
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BLAST of Membrane protein insertase YidC vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Membrane protein insertase YidC vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
OXA16.815e-2327.51Mitochondrial inner membrane insertase; mediates t... [more]
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BLAST of Membrane protein insertase YidC vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO472642.812e-3826.50Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO329229.119e-821.05Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Membrane protein insertase YidC vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 3
Match NameE-valueIdentityDescription
oxa1l8.539e-3731.80OXA1L mitochondrial inner membrane protein [Source... [more]
oxa1l8.982e-3731.80OXA1L mitochondrial inner membrane protein [Source... [more]
cox183.547e-1030.67mitochondrial inner membrane protein COX18 [Source... [more]
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BLAST of Membrane protein insertase YidC vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000039158.10.000e+098.85SMESG000039158.1[more]
SMESG000039158.10.000e+098.85SMESG000039158.1[more]
SMESG000037475.11.820e-3036.50SMESG000037475.1[more]
SMESG000005570.13.365e-1524.24SMESG000005570.1[more]
SMESG000005570.11.713e-1424.24SMESG000005570.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30019526 ID=SMED30019526|Name=Membrane protein insertase YidC|organism=Schmidtea mediterranea sexual|type=transcript|length=1262bp
GTTTAAATAATTGTGTTAAACTTAATTGTATGTTAAACATGTTAATATCT
AAATTTCGACCTGCGACATTATCTCAAAATTATTTTAGTTCCATTCATAA
TGTATATATTCTTAATAGAAAGTTATCTGATATTTCAAATGATAAAATTA
AAGTAAGTGAAATGACTACTGAAATGAATGCTGACGTTTCTAAATATTAT
TTACCTGAACCACCGATGGACCCAGAACTATTACCTAAATTTTTGGATCT
TAATCATTTAGGTGAACCGACATTTAAATCTTTAGGATTAAACAGTTATT
GGCCTTCTGGTTGGGTTCAACATCTTTATGAAATTATGCATGTAGATCTC
GGTCTTCCATGGTGGTCTACAATCGTTGCGAGTAGATTTCCTATGGGAAA
TATTTATATTTTTAAGGTTCTAAATAGGTGGTATAATTATTCGAATGGTC
ATGAGTCCAATTTCTTATAAAATCAAGCAGCTAACTATTATTAATTCTTA
TATATCTCCAAAGATTGTAGATTTTGACAAGAAAATACATTCAGCTAGAG
TCGCAAATGATTCATTATCAATGGCTAAATTATTGCACGATCAACAAAAG
CTATTGAAAAATTCGGAATTCAGTCCAATCAAAAGTATGATTTATTCACT
TTTACAGATTCCCGTATTTCTGTCGGTTATGATTGGTCTTAAAAACATGG
CAGAATTGCCTGTGGCCAGTCTTCAAACCGGTGGTGCGTTTTGGTTTACG
GATTTGACCATGTACGATCCTTACTACATATTGCCTGTTTCGACAATGAT
GCTATTGTTCTTGCAGTTGGAGGTTGGAGCGGATGTAAAGAAGAATACCA
ATTCTGGATATTTAAAATGGGGGATTCGTAGTCTCCCAATTGTTGCTCTT
GCATTCACTTGTCGTTTACCATCGGCTCTTTTGCTTTATTGGTGGACGTC
GTCTTGTATGTCTTTAGTTTTTTCTGGAATAATGTCCATTCCATTTGTAA
AAACACGCTTGGGTCTTTCAGCTCTTAGTTACCAGGCACCAACCGCGACT
GATTCAAAACTTGGATACTTACAAAATTTTAAAGAATCAAATGCTGAAAA
GCGAATAACTAAACTAGCTAAGCAATATCACAATCTTGAACATGAAAATT
GGATTAAAGCAAGAACTTCCTCCATCCCCAAAACGTACAAGTATGATCCA
ACAAAAGTTAACCCAACGCAGTTCAATTAATGTTGTGAATAAATATTAAT
TGTAATTAAAAA
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protein sequence of SMED30019526-orf-1

>SMED30019526-orf-1 ID=SMED30019526-orf-1|Name=SMED30019526-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=156bp
LNNCVKLNCMLNMLISKFRPATLSQNYFSSIHNVYILNRKLSDISNDKIK
VSEMTTEMNADVSKYYLPEPPMDPELLPKFLDLNHLGEPTFKSLGLNSYW
PSGWVQHLYEIMHVDLGLPWWSTIVASRFPMGNIYIFKVLNRWYNYSNGH
ESNFL*
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protein sequence of SMED30019526-orf-2

>SMED30019526-orf-2 ID=SMED30019526-orf-2|Name=SMED30019526-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=262bp
MVMSPISYKIKQLTIINSYISPKIVDFDKKIHSARVANDSLSMAKLLHDQ
QKLLKNSEFSPIKSMIYSLLQIPVFLSVMIGLKNMAELPVASLQTGGAFW
FTDLTMYDPYYILPVSTMMLLFLQLEVGADVKKNTNSGYLKWGIRSLPIV
ALAFTCRLPSALLLYWWTSSCMSLVFSGIMSIPFVKTRLGLSALSYQAPT
ATDSKLGYLQNFKESNAEKRITKLAKQYHNLEHENWIKARTSSIPKTYKY
DPTKVNPTQFN*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: cellular component
TermDefinition
GO:0005886plasma membrane
GO:0016021integral component of membrane
GO:0016020membrane
Vocabulary: biological process
TermDefinition
GO:0015031protein transport
GO:0090150establishment of protein localization to membrane
GO:0051205protein insertion into membrane
Vocabulary: molecular function
TermDefinition
GO:0032977membrane insertase activity
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
PLANA:0000101muscle cell
PLANA:0002109X1 cell
PLANA:0002111X2 cell
Vocabulary: INTERPRO
TermDefinition
IPR001708YidC/ALB3/OXA1/COX18
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 214..234
NoneNo IPR availablePANTHERPTHR12428:SF17MITOCHONDRIAL INNER MEMBRANE PROTEIN OXA1Lcoord: 3..233
NoneNo IPR availableTMHMMTMhelixcoord: 163..185
IPR001708Membrane insertase YidC/ALB3/OXA1/COX18PFAMPF0209660KD_IMPcoord: 2..175
e-value: 7.9E-15
score: 55.1
IPR001708Membrane insertase YidC/ALB3/OXA1/COX18PANTHERPTHR12428OXA1coord: 3..233