Netrin receptor UNC5B
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30019501 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 4
Homology
BLAST of Netrin receptor UNC5B vs. Ensembl Human
Match: UNC5C (unc-5 netrin receptor C [Source:HGNC Symbol;Acc:HGNC:12569]) HSP 1 Score: 317.005 bits (811), Expect = 1.407e-92 Identity = 275/967 (28.44%), Postives = 424/967 (43.85%), Query Frame = 2
Query: 341 EGIPSFIKEPESVYYVYEKKPAKIVCIAEPVSHVNIICNKEVFSYMDLELSE-----SNLRVRKMNKNNEDDLTNGHRWMFSLEITYNQVTEWFN--TFSCVCEAWNQIPSLRLAKKVHSRYGVIKEAYFKSNFKKVPQSKTVVKGQSLILTCVPPESKPKAQVQWMKNKKRL--FENNRIKIVEEHQLLIEDTLLTDSGNYSCIAISLEEKRYSPIAIVKIQESVTENPATQWSAWSACDGNCKK---TRTRNC------NSKGVCK----EIDSCTK------------------KECEYNR---AVAPFVKNPNKN-------------GVSTSSLQDARDIAMYVGLFVAVTILVMVITIIFCLIRRKALLPLRSTMRYPLNINGNGVAYDVKNSLIKNSNTISTKNPYIMDTSLANLTQQRSYLSQSPPNLPPPTCLSEISSTNAYSTGIDFSYNSTGSG--KFSQPLIXXXXXXXXXXXXXXXXXXXXDHKPDPLTVSGTPINSRPPSALYHE-LSLDRESICNSPPFVSENIDISTLAWGTISTIGGRLCLPQSGITLTIAPGSFINSSSSEMYLAVSRNDPNPPILSDNETLLTPIVLFGPKDVPILKPCVLSVPHSADLRQGNWVIRLLSCVLPDQNDELKEPLCQPIWKNIATIGCETDQTPIYTHLDPYAAFIMLDQPQKICLVGQSYPGGKATKRLRLAAFGRPLSTSSYLPNYNIRIYVFSDTKEAFESVSTIETKLGSTLLDITYQIIFSDSMGNLFFCIEELSTG-WKSQLTTKYQEIPFQDIWSGSQSETLHCAFTFDNIDPSQQSLTCRITAYQSGFYNQKQVITIKQDKLDRSNHKRDLIQHEKVLLYSESNNTYLDPLMTVFRISNATRKKLCFLLDNVTPRGNDWKQLCRQLSLNGYLNYFMSKVSPTDALVTLWESRNRNENALIDLIISLKAIGRTDCSTLLESD 3061
E +P F+ EPE Y V + KP + C A P + + CN E D + E S L VR++ S+EI+ QV E F + C C AW+ A SR ++ AY + F++ P K V Q ++L C PPE P A+V+W+KN+ + E+ I +H L+I+ L+D+ NY+C+A ++ KR S A V + + W+ WS C+ C + RTR C N C+ + +CT EC + R AP KN K+ G+ + D+ D+A+YVG + I V+V I ++ AL R R D ++ +I +S P N+ R L PP+L +S A G ++ + + P++ + + + +++ D + T +P ++ S L +E LSL +S+ + D S A+G+ +++GG L +P SG++L I G+ EMY+ V R + P + D++TLLTP+V GP + +P VL++ H AD +W I LK Q W+++ +G E TP Y LD A I+ + LVG S A KRL+LA FG PL SS Y+IR+Y DT++A + + +E ++G LL+ + F S NL I +++ WKS+L KYQEIPF +WSGSQ LHC FT + + L C++ Q Q I Q S + + L +N + F I R+KLC LD RG+DW+ L +L+L+ YLNYF +K SPT ++ LWE++N + L L L+ +GR + L ++
Sbjct: 18 EPLPHFLIEPEEAYIV-KNKPVNLYCKASPATQIYFKCNSEWVHQKDHIVDERVDETSGLIVREV----------------SIEISRQQVEELFGPEDYWCQCVAWSS------AGTTKSRKAYVRIAYLRKTFEQEPLGKEVSLEQEVLLQCRPPEGIPVAEVEWLKNEDIIDPVEDRNFYITIDHNLIIKQARLSDTANYTCVAKNIVAKRKSTTATVIV---YVNGGWSTWTEWSVCNSRCGRGYQKRTRTCTNPAPLNGGAFCEGQSVQKIACTTLCPVDGRWTPWSKWSTCGTECTHWRRRECTAPAPKNGGKDCDGLVLQSKNCTDGLCMQTAPDSDDVALYVG----IVIAVIVCLAISVVV---ALFVYRKNHR------------DFESDIIDSSALNGGFQP-------VNIKAARQDLLAVPPDL---------TSAAAMYRGPVYALHDVSDKIPMTNSPILDPLPNLKIKVYNTSGAVTPQDDLSE-FTSKLSPQMTQ--SLLENEALSLKNQSL-------ARQTDPSCTAFGSFNSLGGHLIVPNSGVSLLIPAGAIPQGRVYEMYVTVHRKETMRPPMDDSQTLLTPVVSCGPPGALLTRPVVLTMHHCADPNTEDWKIL------------LKNQAAQGQWEDVVVVGEENFTTPCYIQLDAEACHILTENLSTYALVGHSTTKA-AAKRLKLAIFG-PLCCSSL--EYSIRVYCLDDTQDALKEILHLERQMGGQLLEEPKALHFKGSTHNLRLSIHDIAHSLWKSKLLAKYQEIPFYHVWSGSQ-RNLHCTFTLERFSLNTVELVCKLCVRQVEGEGQ-----IFQLNCTVSEEPTGI----DLPLLDPANTITTVTGPSAFSIPLPIRQKLCSSLDAPQTRGHDWRMLAHKLNLDRYLNYFATKSSPTGVILDLWEAQNFPDGNLSMLAAVLEEMGRHETVVSLAAE 887
BLAST of Netrin receptor UNC5B vs. Ensembl Human
Match: UNC5C (unc-5 netrin receptor C [Source:HGNC Symbol;Acc:HGNC:12569]) HSP 1 Score: 317.005 bits (811), Expect = 3.207e-92 Identity = 281/986 (28.50%), Postives = 439/986 (44.52%), Query Frame = 2
Query: 299 EDENDFVKLNES----KLEGIPSFIKEPESVYYVYEKKPAKIVCIAEPVSHVNIICNKEVFSYMDLELSE-----SNLRVRKMNKNNEDDLTNGHRWMFSLEITYNQVTEWFN--TFSCVCEAWNQIPSLRLAKKVHSRYGVIKEAYFKSNFKKVPQSKTVVKGQSLILTCVPPESKPKAQVQWMKNKKRL--FENNRIKIVEEHQLLIEDTLLTDSGNYSCIAISLEEKRYSPIAIVKIQESVTENPATQWSAWSACDGNCKK---TRTRNC------NSKGVCK----EIDSCT------------------KKECEYNR---AVAPFVKNPNKN-------------GVSTSSLQDARDIAMYVGLFVAVTILVMVITIIFCLIRRKALLPLRSTMRYPLNINGNGVAYDVKNSLIKNSNTISTKNPYIMDTSLANLTQQRSYLSQSPPNLPPPTCLSEISSTNAYSTGIDFSYNSTGSGKF---SQPLIXXXXXXXXXXXXXXXXXXXXDHKPDPLTVSGTPINSRPPSALYHE-LSLDRESICNSPPFVSENIDISTLAWGTISTIGGRLCLPQSGITLTIAPGSFINSSSSEMYLAVSRNDPNPPILSDNETLLTPIVLFGPKDVPILKPCVLSVPHSADLRQGNWVIRLLSCVLPDQNDELKEPLCQPIWKNIATIGCETDQTPIYTHLDPYAAFIMLDQPQKICLVGQSYPGGKATKRLRLAAFGRPLSTSSYLPNYNIRIYVFSDTKEAFESVSTIETKLGSTLLDITYQIIFSDSMGNLFFCIEELSTG-WKSQLTTKYQEIPFQDIWSGSQSETLHCAFTFDNIDPSQQSLTCRITAYQSGFYNQKQVITIKQDKLDRSNHKRDLIQHEKVLLYSESNNTYLDPLMTVFRISNATRKKLCFLLDNVTPRGNDWKQLCRQLSLNGYLNYFMSKVSPTDALVTLWESRNRNENALIDLIISLKAIGRTDCSTLLESD 3061
+D++ F +L E+ E +P F+ EPE Y V + KP + C A P + + CN E D + E S L VR++ S+EI+ QV E F + C C AW+ A SR ++ AY + F++ P K V Q ++L C PPE P A+V+W+KN+ + E+ I +H L+I+ L+D+ NY+C+A ++ KR S A V + + W+ WS C+ C + RTR C N C+ + +CT EC + R AP KN K+ G+ + D+ D+A+YVG + I V+V I ++ AL R R D ++ +I +S P N+ R L PP+L +S A G ++ + S K + P++ + + + +++ D + T +P ++ S L +E LSL +S+ + D S A+G+ +++GG L +P SG++L I G+ EMY+ V R + P + D++TLLTP+V GP + +P VL++ H AD +W I LK Q W+++ +G E TP Y LD A I+ + LVG S A KRL+LA FG PL SS Y+IR+Y DT++A + + +E ++G LL+ + F S NL I +++ WKS+L KYQEIPF +WSGSQ LHC FT + + L C++ Q + Q+ + + DL +L + + T P + F I R+KLC LD RG+DW+ L +L+L+ YLNYF +K SPT ++ LWE++N + L L L+ +GR + L ++
Sbjct: 41 QDDDFFHELPETFPSDPPEPLPHFLIEPEEAYIV-KNKPVNLYCKASPATQIYFKCNSEWVHQKDHIVDERVDETSGLIVREV----------------SIEISRQQVEELFGPEDYWCQCVAWSS------AGTTKSRKAYVRIAYLRKTFEQEPLGKEVSLEQEVLLQCRPPEGIPVAEVEWLKNEDIIDPVEDRNFYITIDHNLIIKQARLSDTANYTCVAKNIVAKRKSTTATVIV---YVNGGWSTWTEWSVCNSRCGRGYQKRTRTCTNPAPLNGGAFCEGQSVQKIACTTLCPVDGRWTPWSKWSTCGTECTHWRRRECTAPAPKNGGKDCDGLVLQSKNCTDGLCMQTAPDSDDVALYVG----IVIAVIVCLAISVVV---ALFVYRKNHR------------DFESDIIDSSALNGGFQP-------VNIKAARQDLLAVPPDL---------TSAAAMYRGPVYALHDV-SDKIPMTNSPILDPLPNLKIKVYNTSGAVTPQDDLSE-FTSKLSPQMTQ--SLLENEALSLKNQSL-------ARQTDPSCTAFGSFNSLGGHLIVPNSGVSLLIPAGAIPQGRVYEMYVTVHRKETMRPPMDDSQTLLTPVVSCGPPGALLTRPVVLTMHHCADPNTEDWKIL------------LKNQAAQGQWEDVVVVGEENFTTPCYIQLDAEACHILTENLSTYALVGHSTTKA-AAKRLKLAIFG-PLCCSSL--EYSIRVYCLDDTQDALKEILHLERQMGGQLLEEPKALHFKGSTHNLRLSIHDIAHSLWKSKLLAKYQEIPFYHVWSGSQ-RNLHCTFTLERFSLNTVELVCKLCVRQ--VEGEGQIFQLNC-TVSEEPTGIDL----PLLDPANTITTVTGP--SAFSIPLPIRQKLCSSLDAPQTRGHDWRMLAHKLNLDRYLNYFATKSSPTGVILDLWEAQNFPDGNLSMLAAVLEEMGRHETVVSLAAE 928
BLAST of Netrin receptor UNC5B vs. Ensembl Human
Match: UNC5B (unc-5 netrin receptor B [Source:HGNC Symbol;Acc:HGNC:12568]) HSP 1 Score: 230.335 bits (586), Expect = 5.404e-62 Identity = 137/421 (32.54%), Postives = 217/421 (51.54%), Query Frame = 2
Query: 1802 GTISTIGGRLCLPQSGITLTIAPGSFINSSSSEMYLAVSRNDPNPPILSDNETLLTPIVLFGPKDVPILKPCVLSVPHSADLRQGNWVIRLLSCVLPDQNDELKEPLCQPIWKNIATIGCETDQTPIYTHLDPYAAFIMLDQPQKICLVGQSYPGGKATKRLRLAAFGRPLSTSSYLPNYNIRIYVFSDTKEAFESVSTIETKLGSTLLDITYQIIFSDSMGNLFFCIEEL-STGWKSQLTTKYQEIPFQDIWSGSQSETLHCAFTFDNIDPSQQSLTCRITAYQSGFYNQKQVITIKQDKLDRSNHKRDLIQHEKVLLYSESNNTYLDPLMTVFRISNATRKKLCFLLDNVTPRGNDWKQLCRQLSLNGYLNYFMSKVSPTDALVTLWESRNRNENALIDLIISLKAIGRTDCSTLLESD 3061
GT +GGRL +P +G++L + G+ EMYL +++ + P+ +T+L+P V GP + + +P +L++PH A++ +W+ +LK Q W+ + T+ ET TP Y L+P A I+LDQ G+SY A KRL+LA F L TS Y++R+Y DT A + V +E LG L++ ++F DS NL + +L W+S+L KYQEIPF IWSGSQ + LHC FT + + LTC+I Q + Q+ + + D + + T L P F+I + R+K+C LD RGNDW+ L ++LS++ YLNYF +K SPT ++ LWE+ +++ L L +L+ +G+++ + +D
Sbjct: 536 GTFGCLGGRLSIPGTGVSLLVPNGAIPQGKFYEMYLLINKAESTLPLSEGTQTVLSPSVTCGPTGLLLCRPVILTMPHCAEVSARDWIF------------QLKTQAHQGHWEEVVTLDEETLNTPCYCQLEPRACHILLDQLGTYVFTGESY-SRSAVKRLQLAVFAPALCTSL---EYSLRVYCLEDTPVALKEVLELERTLGGYLVEEPKPLMFKDSYHNLRLSLHDLPHAHWRSKLLAKYQEIPFYHIWSGSQ-KALHCTFTLERHSLASTELTCKICVRQ--VEGEGQIFQLHTTLAETPAGSLDTLCSAP----GSTVTTQLGPY--AFKIPLSIRQKICNSLDAPNSRGNDWRMLAQKLSMDRYLNYFATKASPTGVILDLWEALQQDDGDLNSLASALEEMGKSEMLVAVATD 931 HSP 2 Score: 117.087 bits (292), Expect = 6.355e-26 Identity = 96/372 (25.81%), Postives = 161/372 (43.28%), Query Frame = 2
Query: 341 EGIPSFIKEPESVYYVYEKKPAKIVCIAEPVSHVNIICNKEVFSYMDLELSE-----SNLRVRKMNKNNEDDLTNGHRWMFSLEITYNQVTEWFN--TFSCVCEAWNQIPSLRLAKKVHSRYGVIKEAYFKSNFKKVPQSKTVVKGQSLILTCVPPESKPKAQVQWMKNKKRL--FENNRIKIVEEHQLLIEDTLLTDSGNYSCIAISLEEKRYSPIAIVKIQESVTENPATQWSAWSACDGNCKKT---RTRNC------NSKGVCK----EIDSCT------------------KKECEYNRA---VAPFVKNPNK-------------NGVSTSSLQDARDIAMYVGLFVAVTILVMVITIIFCLIRRK 1288
E +P F++EP+ Y V + KP ++ C A P + + CN E S D E + LRVR++ +E++ QV E F + C C AW+ A SR ++ AY + NF + P K V ++L C PPE P A+V+W+KN+ + ++ + +H L+I L+D+ NY+C+A ++ KR S A V + + W+ WS C C + RTR C N C+ + +CT EC + R+ +AP +N + +G+ L+ + D A+Y GL VA+ ++V ++ + ++ R+
Sbjct: 45 EPLPYFLQEPQDAYIV-KNKPVELRCRAFPATQIYFKCNGEWVSQNDHVTQEGLDEATGLRVREVQ----------------IEVSRQQVEELFGLEDYWCQCVAWSS------AGTTKSRRAYVRIAYLRKNFDQEPLGKEVPLDHEVLLQCRPPEGVPVAEVEWLKNEDVIDPTQDTNFLLTIDHNLIIRQARLSDTANYTCVAKNIVAKRRSTTATVIV---YVNGGWSSWAEWSPCSNRCGRGWQKRTRTCTNPAPLNGGAFCEGQAFQKTACTTICPVDGAWTEWSKWSACSTECAHWRSRECMAPPPQNGGRDCSGTLLDSKNCTDGLCMQMLEASGDAALYAGLVVAIFVVVAILMAVGVVVYRR 390
BLAST of Netrin receptor UNC5B vs. Ensembl Human
Match: UNC5B (unc-5 netrin receptor B [Source:HGNC Symbol;Acc:HGNC:12568]) HSP 1 Score: 230.335 bits (586), Expect = 5.869e-62 Identity = 137/421 (32.54%), Postives = 217/421 (51.54%), Query Frame = 2
Query: 1802 GTISTIGGRLCLPQSGITLTIAPGSFINSSSSEMYLAVSRNDPNPPILSDNETLLTPIVLFGPKDVPILKPCVLSVPHSADLRQGNWVIRLLSCVLPDQNDELKEPLCQPIWKNIATIGCETDQTPIYTHLDPYAAFIMLDQPQKICLVGQSYPGGKATKRLRLAAFGRPLSTSSYLPNYNIRIYVFSDTKEAFESVSTIETKLGSTLLDITYQIIFSDSMGNLFFCIEEL-STGWKSQLTTKYQEIPFQDIWSGSQSETLHCAFTFDNIDPSQQSLTCRITAYQSGFYNQKQVITIKQDKLDRSNHKRDLIQHEKVLLYSESNNTYLDPLMTVFRISNATRKKLCFLLDNVTPRGNDWKQLCRQLSLNGYLNYFMSKVSPTDALVTLWESRNRNENALIDLIISLKAIGRTDCSTLLESD 3061
GT +GGRL +P +G++L + G+ EMYL +++ + P+ +T+L+P V GP + + +P +L++PH A++ +W+ +LK Q W+ + T+ ET TP Y L+P A I+LDQ G+SY A KRL+LA F L TS Y++R+Y DT A + V +E LG L++ ++F DS NL + +L W+S+L KYQEIPF IWSGSQ + LHC FT + + LTC+I Q + Q+ + + D + + T L P F+I + R+K+C LD RGNDW+ L ++LS++ YLNYF +K SPT ++ LWE+ +++ L L +L+ +G+++ + +D
Sbjct: 547 GTFGCLGGRLSIPGTGVSLLVPNGAIPQGKFYEMYLLINKAESTLPLSEGTQTVLSPSVTCGPTGLLLCRPVILTMPHCAEVSARDWIF------------QLKTQAHQGHWEEVVTLDEETLNTPCYCQLEPRACHILLDQLGTYVFTGESY-SRSAVKRLQLAVFAPALCTSL---EYSLRVYCLEDTPVALKEVLELERTLGGYLVEEPKPLMFKDSYHNLRLSLHDLPHAHWRSKLLAKYQEIPFYHIWSGSQ-KALHCTFTLERHSLASTELTCKICVRQ--VEGEGQIFQLHTTLAETPAGSLDTLCSAP----GSTVTTQLGPY--AFKIPLSIRQKICNSLDAPNSRGNDWRMLAQKLSMDRYLNYFATKASPTGVILDLWEALQQDDGDLNSLASALEEMGKSEMLVAVATD 942 HSP 2 Score: 115.931 bits (289), Expect = 1.468e-25 Identity = 97/388 (25.00%), Postives = 159/388 (40.98%), Query Frame = 2
Query: 341 EGIPSFIKEPESVYYVYEKKPAKIVCIAEPVSHVNIICNKEVFSYMDLELSE-----SNLRVRKMNKNNEDDLTNGHRWMFSLEITYNQVTEWFN--TFSCVCEAWNQIPSLRLAKKVHSRYGVIKEAYFKSNFKKVPQSKTVVKGQSLILTCVPPESKPKAQVQWMKNKKRL--FENNRIKIVEEHQLLIEDTLLTDSGNYSCIAISLEEKRYSPIAIVKI-------------------------QESVTENPA----------------------------TQWSAWSACDGNCKKTRTRNC----------NSKGVCKEIDSCTKKECEYNRAVAPFVKNPNKNGVSTSSLQDARDIAMYVGLFVAVTILVMVITIIFCLIRRK 1288
E +P F++EP+ Y V + KP ++ C A P + + CN E S D E + LRVR++ +E++ QV E F + C C AW+ A SR ++ AY + NF + P K V ++L C PPE P A+V+W+KN+ + ++ + +H L+I L+D+ NY+C+A ++ KR S A V + + NPA T+WS WSAC C R+R C + G + +CT C N+ + +PN + L+ + D A+Y GL VA+ ++V ++ + ++ R+
Sbjct: 45 EPLPYFLQEPQDAYIV-KNKPVELRCRAFPATQIYFKCNGEWVSQNDHVTQEGLDEATGLRVREVQ----------------IEVSRQQVEELFGLEDYWCQCVAWSS------AGTTKSRRAYVRIAYLRKNFDQEPLGKEVPLDHEVLLQCRPPEGVPVAEVEWLKNEDVIDPTQDTNFLLTIDHNLIIRQARLSDTANYTCVAKNIVAKRRSTTATVIVYVNGGWSSWAEWSPCSNRCGRGWQKRTRTCTNPAPLNGGAFCEGQAFQKTACTTICPVDGAWTEWSKWSACSTECAHWRSRECMAPPPQNGGRDCSGTLLDSKNCTDGLCMQNKKT---LSDPNSH-----LLEASGDAALYAGLVVAIFVVVAILMAVGVVVYRR 401
BLAST of Netrin receptor UNC5B vs. Ensembl Human
Match: UNC5C (unc-5 netrin receptor C [Source:HGNC Symbol;Acc:HGNC:12569]) HSP 1 Score: 213.386 bits (542), Expect = 3.006e-57 Identity = 210/790 (26.58%), Postives = 329/790 (41.65%), Query Frame = 2
Query: 299 EDENDFVKLNES----KLEGIPSFIKEPESVYYVYEKKPAKIVCIAEPVSHVNIICNKEVFSYMDLELSE-----SNLRVRKMNKNNEDDLTNGHRWMFSLEITYNQVTEWFN--TFSCVCEAWNQIPSLRLAKKVHSRYGVIKEAYFKSNFKKVPQSKTVVKGQSLILTCVPPESKPKAQVQWMKNKKRL--FENNRIKIVEEHQLLIEDTLLTDSGNYSCIAISLEEKRYSPIAIVKI-------------------------QESVTENPA----------------------------TQWSAWSACDGNCKKTRTRNCNS----------KGVCKEIDSCTKKECEYNRAVAPFVKNPNKNGVSTSSLQDARDIAMYVGLFVAVTILVMVITIIFCLIRRKALLPLRSTMRYPLNINGNGVAYDVKNSLIKNSNTISTKNPYIMDTSLANLTQQRSYLSQSPPNLPPPTCLSEISSTNAYSTGIDFSYNSTGSGKF---SQPLIXXXXXXXXXXXXXXXXXXXXDHKPDPLTVSGTPINSRPPSALYHE-LSLDRESICNSPPFVSENIDISTLAWGTISTIGGRLCLPQSGITLTIAPGSFINSSSSEMYLAVSRNDPNPPILSDNETLLTPIVLFGPKDVPILKPCVLSVPHSADLRQGNWVIRLLSCVLPDQNDELKEPLCQPIWKNIATIGCETDQTPIYTHLDPYAAFIMLDQPQKICLVGQSYPGGKATKRLRLAAFGRPLSTSSYLPNYNIRIYVFSDTKEAFESVSTIETKLGSTLL 2428
+D++ F +L E+ E +P F+ EPE Y V + KP + C A P + + CN E D + E S L VR++ S+EI+ QV E F + C C AW+ A SR ++ AY + F++ P K V Q ++L C PPE P A+V+W+KN+ + E+ I +H L+I+ L+D+ NY+C+A ++ KR S A V + + NPA T WS WS C C R R C + G+ + +CT C + + +N SS D+ D+A+YVG + I V+V I ++ AL R R D ++ +I +S P N+ R L PP+L +S A G ++ + S K + P++ + + + +++ D + T +P ++ S L +E LSL +S+ + D S A+G+ +++GG L +P SG++L I G+ EMY+ V R + P + D++TLLTP+V GP + +P VL++ H AD +W I LK Q W+++ +G E TP Y LD A I+ + LVG S A KRL+LA FG PL SS Y+IR+Y DT++A + + +E ++G LL
Sbjct: 41 QDDDFFHELPETFPSDPPEPLPHFLIEPEEAYIV-KNKPVNLYCKASPATQIYFKCNSEWVHQKDHIVDERVDETSGLIVREV----------------SIEISRQQVEELFGPEDYWCQCVAWSS------AGTTKSRKAYVRIAYLRKTFEQEPLGKEVSLEQEVLLQCRPPEGIPVAEVEWLKNEDIIDPVEDRNFYITIDHNLIIKQARLSDTANYTCVAKNIVAKRKSTTATVIVYVNGGWSTWTEWSVCNSRCGRGYQKRTRTCTNPAPLNGGAFCEGQSVQKIACTTLCPVDGRWTPWSKWSTCGTECTHWRRRECTAPAPKNGGKDCDGLVLQSKNCTDGLCMQSFIYPISTEQRTQNEYGFSSAPDSDDVALYVG----IVIAVIVCLAISVVV---ALFVYRKNHR------------DFESDIIDSSALNGGFQP-------VNIKAARQDLLAVPPDL---------TSAAAMYRGPVYALHDV-SDKIPMTNSPILDPLPNLKIKVYNTSGAVTPQDDLSE-FTSKLSPQMTQ--SLLENEALSLKNQSL-------ARQTDPSCTAFGSFNSLGGHLIVPNSGVSLLIPAGAIPQGRVYEMYVTVHRKETMRPPMDDSQTLLTPVVSCGPPGALLTRPVVLTMHHCADPNTEDWKIL------------LKNQAAQGQWEDVVVVGEENFTTPCYIQLDAEACHILTENLSTYALVGHSTTKA-AAKRLKLAIFG-PLCCSSL--EYSIRVYCLDDTQDALKEILHLERQMGGQLL 745
BLAST of Netrin receptor UNC5B vs. Ensembl Celegans
Match: unc-5 (Netrin receptor unc-5 [Source:UniProtKB/Swiss-Prot;Acc:Q26261]) HSP 1 Score: 114.775 bits (286), Expect = 1.107e-25 Identity = 178/721 (24.69%), Postives = 282/721 (39.11%), Query Frame = 2
Query: 1007 TQWSAWSACDGNCKKTRTRNC------NSKGVCKEIDSCTKKECEYNRAVAPFVKNPNKNGVSTSSLQDARDIAMY--VGLFVAVTILVMVITIIFCLIR--RKALLPLRSTMRYPLNIN---GNGVAYD----VKNSLIKNSNTISTKNPYIMDTSLANLTQQRSYLSQSPPNLPPPTCLSEISSTNAYSTGIDFSYNSTGSGKFSQPLIXXXXXXXXXXXXXXXXXXXXDHKPDPLTVSGTPINSRPPSALYHELSLDRESICNSPPFVSENIDIS-TLAWGTISTIGGRLCLPQSGITLTIAPGSFINSSSSEMYLAVSRNDPNPPILSDNETLLTPIVLFGPKDVP-------ILKPCVLSVPHSAD-LRQGNWVIRLLSCVLPDQNDELKEPLCQPIWKNIATIGCETDQTPIYTHL-------DPYA-AFIMLDQPQKICLVGQSYPGG-KATKRLRLAAFGRPLSTSSYLPNYNIRIYVFSDTKEAFESVSTIETKLGSTLLDITYQIIFSDSMGNLFFCIEELSTGWKSQLTTKYQEIPFQDIWSGSQSETLHCAFTFDNIDPSQQSLTCRITAYQSGFYNQKQVITIKQDKLDRSNHKRDLIQHEKVLLYSESNNTYLDPLMTVFRISNATRKKLCFLLDNVTPRGNDWKQLCRQLSLNGYLNYFMS--KVSPTDALVTLWE-SRNRNENALIDLIISLKAIGRTDCSTLLE 3055
+ WS WSAC +C + RTR C N C D T+ EC P + + SS D A+Y V V ++ I +FC R K PL+ P +N G+ Y V+ L+++ + ++ +++ +Q Y PP LP T L S +A+S Y+ST + LI SS+S+ + K L S + + A ++ D+ + +D S + I + G RL L +SG L + +YLAVS + P L E+ L+P+++ G DV + +P V+S H A + NW L + DE W+ TIG E T ++ D + +M ++ L G A KR+ LA FG P S+Y + +R+Y +T A ESV E GS LL + I ++ GNL CIE++ G+ + Q + LHC+ F + + + R+ YQ + V+ + +E L + S + FR+ + +L LLD +DW+ L ++L + YL +F S SPT L+ LWE S + + A+ DL+ +L+ +GR D +LE
Sbjct: 170 SSWSDWSACSSSCHRYRTRACTVPPPMNGGQPCFGDDLMTQ-EC------------PAQLCTADSSRIVISDTAVYGSVASIFIVASFILAILAMFCCKRGNSKKSKPLK-----PQKMNSEKAGGIYYSEPPGVRRLLLEHQHGT------LLGEKISSCSQ---YFE--PPPLPHSTTLR--SGKSAFS-----GYSSTRNAGSRAALIQECSSSSSGSGG----------KRTMLRTSSSNCSDDDNYATLYDYMEDKSVL---------GLDTSQNIVAAQIDSNGARLSLSKSGARLIVP--ELAVEGEKMLYLAVSDTLTDQPHLKPIESALSPVIVIGQCDVSMSAHDNILRRPVVVSFRHCASTFPRDNWQFTLYA-------DEGSG------WQKAVTIGEENLNTNMFVQFEQPGKKNDGFGWCHVMTYSLARLMLAGHPRRNSLSAAKRVHLAVFG-PTEMSAYRRPFELRVYCVPETGAAMESVWKQED--GSRLLCESNDFILNEK-GNLCICIEDVIPGFSCDGPEVVEISETQHRFVAQNG--LHCSLKFRPKEINGSQFSTRVIVYQKASSTEPMVMEVS---------------NEPELYDATSEEREKGSVCVEFRLPFGVKDELARLLDMPNESHSDWRGLAKKLHYDRYLQFFASFPDCSPTSLLLDLWEASSSGSARAVPDLLQTLRVMGRPDAVMVLE 799 HSP 2 Score: 60.8474 bits (146), Expect = 4.288e-9 Identity = 40/156 (25.64%), Postives = 70/156 (44.87%), Query Frame = 2
Query: 707 FKSNFKKVPQSKTVVKGQSLILTCVPPESKPKAQVQWMKNKKRLFENNRIKIVEEHQLLIEDTLLTDSGNYSCIAISLEEKRYSPIAIVKIQESVTENPATQWSAW-SACDGNC------------------KKTRTRNCNSKGVCKEIDSCTKKE 1117
+ +F K P ++ V +G +L L C PES PKA++ W K+ + + + + L++ L+DSGNY+C A ++ R + V+I + ++WS W C +C + RTR CN+ + + C +E
Sbjct: 1 MRKHFLKSPVAQRVQEGTTLQLPCQAPESDPKAELTWYKDGVVVQPDANVIRASDGSLIMSAARLSDSGNYTCEATNVANSRKTDPVEVQI---YVDGGWSEWSPWIGTCHVDCPLLRQHAHRIRDPHDVLPHQRRTRTCNNPAPLNDGEYCKGEE 153
BLAST of Netrin receptor UNC5B vs. Ensembl Celegans
Match: unc-5 (Netrin receptor unc-5 [Source:UniProtKB/Swiss-Prot;Acc:Q26261]) HSP 1 Score: 114.775 bits (286), Expect = 1.321e-25 Identity = 178/721 (24.69%), Postives = 282/721 (39.11%), Query Frame = 2
Query: 1007 TQWSAWSACDGNCKKTRTRNC------NSKGVCKEIDSCTKKECEYNRAVAPFVKNPNKNGVSTSSLQDARDIAMY--VGLFVAVTILVMVITIIFCLIR--RKALLPLRSTMRYPLNIN---GNGVAYD----VKNSLIKNSNTISTKNPYIMDTSLANLTQQRSYLSQSPPNLPPPTCLSEISSTNAYSTGIDFSYNSTGSGKFSQPLIXXXXXXXXXXXXXXXXXXXXDHKPDPLTVSGTPINSRPPSALYHELSLDRESICNSPPFVSENIDIS-TLAWGTISTIGGRLCLPQSGITLTIAPGSFINSSSSEMYLAVSRNDPNPPILSDNETLLTPIVLFGPKDVP-------ILKPCVLSVPHSAD-LRQGNWVIRLLSCVLPDQNDELKEPLCQPIWKNIATIGCETDQTPIYTHL-------DPYA-AFIMLDQPQKICLVGQSYPGG-KATKRLRLAAFGRPLSTSSYLPNYNIRIYVFSDTKEAFESVSTIETKLGSTLLDITYQIIFSDSMGNLFFCIEELSTGWKSQLTTKYQEIPFQDIWSGSQSETLHCAFTFDNIDPSQQSLTCRITAYQSGFYNQKQVITIKQDKLDRSNHKRDLIQHEKVLLYSESNNTYLDPLMTVFRISNATRKKLCFLLDNVTPRGNDWKQLCRQLSLNGYLNYFMS--KVSPTDALVTLWE-SRNRNENALIDLIISLKAIGRTDCSTLLE 3055
+ WS WSAC +C + RTR C N C D T+ EC P + + SS D A+Y V V ++ I +FC R K PL+ P +N G+ Y V+ L+++ + ++ +++ +Q Y PP LP T L S +A+S Y+ST + LI SS+S+ + K L S + + A ++ D+ + +D S + I + G RL L +SG L + +YLAVS + P L E+ L+P+++ G DV + +P V+S H A + NW L + DE W+ TIG E T ++ D + +M ++ L G A KR+ LA FG P S+Y + +R+Y +T A ESV E GS LL + I ++ GNL CIE++ G+ + Q + LHC+ F + + + R+ YQ + V+ + +E L + S + FR+ + +L LLD +DW+ L ++L + YL +F S SPT L+ LWE S + + A+ DL+ +L+ +GR D +LE
Sbjct: 278 SSWSDWSACSSSCHRYRTRACTVPPPMNGGQPCFGDDLMTQ-EC------------PAQLCTADSSRIVISDTAVYGSVASIFIVASFILAILAMFCCKRGNSKKSKPLK-----PQKMNSEKAGGIYYSEPPGVRRLLLEHQHGT------LLGEKISSCSQ---YFE--PPPLPHSTTLR--SGKSAFS-----GYSSTRNAGSRAALIQECSSSSSGSGG----------KRTMLRTSSSNCSDDDNYATLYDYMEDKSVL---------GLDTSQNIVAAQIDSNGARLSLSKSGARLIVP--ELAVEGEKMLYLAVSDTLTDQPHLKPIESALSPVIVIGQCDVSMSAHDNILRRPVVVSFRHCASTFPRDNWQFTLYA-------DEGSG------WQKAVTIGEENLNTNMFVQFEQPGKKNDGFGWCHVMTYSLARLMLAGHPRRNSLSAAKRVHLAVFG-PTEMSAYRRPFELRVYCVPETGAAMESVWKQED--GSRLLCESNDFILNEK-GNLCICIEDVIPGFSCDGPEVVEISETQHRFVAQNG--LHCSLKFRPKEINGSQFSTRVIVYQKASSTEPMVMEVS---------------NEPELYDATSEEREKGSVCVEFRLPFGVKDELARLLDMPNESHSDWRGLAKKLHYDRYLQFFASFPDCSPTSLLLDLWEASSSGSARAVPDLLQTLRVMGRPDAVMVLE 907 HSP 2 Score: 70.8626 bits (172), Expect = 4.660e-12 Identity = 64/267 (23.97%), Postives = 115/267 (43.07%), Query Frame = 2
Query: 383 YVYEKKPAKIVCIAEPVSHVNIICNKEVFSYMDLELSESNLRVRKMNKNNEDDLTNGHRWM-FSLEITYNQV--TEWFNTFSCVCEAWNQIPSLRLAKKVHSRYGVIKEAYFKSNFKKVPQSKTVVKGQSLILTCVPPESKPKAQVQWMKNKKRLFENNRIKIVEEHQLLIEDTLLTDSGNYSCIAISLEEKRYSPIAIVKIQESVTENPATQWSAW-SACDGNC------------------KKTRTRNCNSKGVCKEIDSCTKKE 1117
YV KP ++ C A + + C+ + ++D + R+ K+ D T+G ++ S++I+ V + + F C C A +A V + AY + +F K P ++ V +G +L L C PES PKA++ W K+ + + + + L++ L+DSGNY+C A ++ R + V+I + ++WS W C +C + RTR CN+ + + C +E
Sbjct: 14 YVIRNKPLRLQCRANHATKIRYKCSSK---WID------DSRIEKLIGT---DSTSGVGYIDASVDISRIDVDTSGHVDAFQCQCYASGDDDQDVVASDV----ATVHLAYMRKHFLKSPVAQRVQEGTTLQLPCQAPESDPKAELTWYKDGVVVQPDANVIRASDGSLIMSAARLSDSGNYTCEATNVANSRKTDPVEVQI---YVDGGWSEWSPWIGTCHVDCPLLRQHAHRIRDPHDVLPHQRRTRTCNNPAPLNDGEYCKGEE 261
BLAST of Netrin receptor UNC5B vs. Ensembl Celegans
Match: unc-5 (Netrin receptor unc-5 [Source:UniProtKB/Swiss-Prot;Acc:Q26261]) HSP 1 Score: 114.005 bits (284), Expect = 2.286e-25 Identity = 178/721 (24.69%), Postives = 282/721 (39.11%), Query Frame = 2
Query: 1007 TQWSAWSACDGNCKKTRTRNC------NSKGVCKEIDSCTKKECEYNRAVAPFVKNPNKNGVSTSSLQDARDIAMY--VGLFVAVTILVMVITIIFCLIR--RKALLPLRSTMRYPLNIN---GNGVAYD----VKNSLIKNSNTISTKNPYIMDTSLANLTQQRSYLSQSPPNLPPPTCLSEISSTNAYSTGIDFSYNSTGSGKFSQPLIXXXXXXXXXXXXXXXXXXXXDHKPDPLTVSGTPINSRPPSALYHELSLDRESICNSPPFVSENIDIS-TLAWGTISTIGGRLCLPQSGITLTIAPGSFINSSSSEMYLAVSRNDPNPPILSDNETLLTPIVLFGPKDVP-------ILKPCVLSVPHSAD-LRQGNWVIRLLSCVLPDQNDELKEPLCQPIWKNIATIGCETDQTPIYTHL-------DPYA-AFIMLDQPQKICLVGQSYPGG-KATKRLRLAAFGRPLSTSSYLPNYNIRIYVFSDTKEAFESVSTIETKLGSTLLDITYQIIFSDSMGNLFFCIEELSTGWKSQLTTKYQEIPFQDIWSGSQSETLHCAFTFDNIDPSQQSLTCRITAYQSGFYNQKQVITIKQDKLDRSNHKRDLIQHEKVLLYSESNNTYLDPLMTVFRISNATRKKLCFLLDNVTPRGNDWKQLCRQLSLNGYLNYFMS--KVSPTDALVTLWE-SRNRNENALIDLIISLKAIGRTDCSTLLE 3055
+ WS WSAC +C + RTR C N C D T+ EC P + + SS D A+Y V V ++ I +FC R K PL+ P +N G+ Y V+ L+++ + ++ +++ +Q Y PP LP T L S +A+S Y+ST + LI SS+S+ + K L S + + A ++ D+ + +D S + I + G RL L +SG L + +YLAVS + P L E+ L+P+++ G DV + +P V+S H A + NW L + DE W+ TIG E T ++ D + +M ++ L G A KR+ LA FG P S+Y + +R+Y +T A ESV E GS LL + I ++ GNL CIE++ G+ + Q + LHC+ F + + + R+ YQ + V+ + +E L + S + FR+ + +L LLD +DW+ L ++L + YL +F S SPT L+ LWE S + + A+ DL+ +L+ +GR D +LE
Sbjct: 306 SSWSDWSACSSSCHRYRTRACTVPPPMNGGQPCFGDDLMTQ-EC------------PAQLCTADSSRIVISDTAVYGSVASIFIVASFILAILAMFCCKRGNSKKSKPLK-----PQKMNSEKAGGIYYSEPPGVRRLLLEHQHGT------LLGEKISSCSQ---YFE--PPPLPHSTTLR--SGKSAFS-----GYSSTRNAGSRAALIQECSSSSSGSGG----------KRTMLRTSSSNCSDDDNYATLYDYMEDKSVL---------GLDTSQNIVAAQIDSNGARLSLSKSGARLIVP--ELAVEGEKMLYLAVSDTLTDQPHLKPIESALSPVIVIGQCDVSMSAHDNILRRPVVVSFRHCASTFPRDNWQFTLYA-------DEGSG------WQKAVTIGEENLNTNMFVQFEQPGKKNDGFGWCHVMTYSLARLMLAGHPRRNSLSAAKRVHLAVFG-PTEMSAYRRPFELRVYCVPETGAAMESVWKQED--GSRLLCESNDFILNEK-GNLCICIEDVIPGFSCDGPEVVEISETQHRFVAQNG--LHCSLKFRPKEINGSQFSTRVIVYQKASSTEPMVMEVS---------------NEPELYDATSEEREKGSVCVEFRLPFGVKDELARLLDMPNESHSDWRGLAKKLHYDRYLQFFASFPDCSPTSLLLDLWEASSSGSARAVPDLLQTLRVMGRPDAVMVLE 935 HSP 2 Score: 70.8626 bits (172), Expect = 4.088e-12 Identity = 64/267 (23.97%), Postives = 115/267 (43.07%), Query Frame = 2
Query: 383 YVYEKKPAKIVCIAEPVSHVNIICNKEVFSYMDLELSESNLRVRKMNKNNEDDLTNGHRWM-FSLEITYNQV--TEWFNTFSCVCEAWNQIPSLRLAKKVHSRYGVIKEAYFKSNFKKVPQSKTVVKGQSLILTCVPPESKPKAQVQWMKNKKRLFENNRIKIVEEHQLLIEDTLLTDSGNYSCIAISLEEKRYSPIAIVKIQESVTENPATQWSAW-SACDGNC------------------KKTRTRNCNSKGVCKEIDSCTKKE 1117
YV KP ++ C A + + C+ + ++D + R+ K+ D T+G ++ S++I+ V + + F C C A +A V + AY + +F K P ++ V +G +L L C PES PKA++ W K+ + + + + L++ L+DSGNY+C A ++ R + V+I + ++WS W C +C + RTR CN+ + + C +E
Sbjct: 42 YVIRNKPLRLQCRANHATKIRYKCSSK---WID------DSRIEKLIGT---DSTSGVGYIDASVDISRIDVDTSGHVDAFQCQCYASGDDDQDVVASDV----ATVHLAYMRKHFLKSPVAQRVQEGTTLQLPCQAPESDPKAELTWYKDGVVVQPDANVIRASDGSLIMSAARLSDSGNYTCEATNVANSRKTDPVEVQI---YVDGGWSEWSPWIGTCHVDCPLLRQHAHRIRDPHDVLPHQRRTRTCNNPAPLNDGEYCKGEE 289
BLAST of Netrin receptor UNC5B vs. Ensembl Celegans
Match: unc-5 (Netrin receptor unc-5 [Source:UniProtKB/Swiss-Prot;Acc:Q26261]) HSP 1 Score: 110.153 bits (274), Expect = 2.673e-24 Identity = 113/436 (25.92%), Postives = 178/436 (40.83%), Query Frame = 2
Query: 1808 ISTIGGRLCLPQSGITLTIAPGSFINSSSSEMYLAVSRNDPNPPILSDNETLLTPIVLFGPKDVP-------ILKPCVLSVPHSAD-LRQGNWVIRLLSCVLPDQNDELKEPLCQPIWKNIATIGCETDQTPIYTHLDPYA--------AFIMLDQPQKICLVGQSYPGG-KATKRLRLAAFGRPLSTSSYLPNYNIRIYVFSDTKEAFESVSTIETKLGSTLLDITYQIIFSDSMGNLFFCIEELSTGWKSQLTTKYQEIPFQDIWSGSQSETLHCAFTFDNIDPSQQSLTCRITAYQSGFYNQKQVITIKQDKLDRSNHKRDLIQHEKVLLYSESNNTYLDPLMTVFRISNATRKKLCFLLDNVTPRGNDWKQLCRQLSLNGYLNYFMS--KVSPTDALVTLWE-SRNRNENALIDLIISLKAIGRTDCSTLLE 3055
I + G RL L +SG L + +YLAVS + P L E+ L+P+++ G DV + +P V+S H A + NW L + DE W+ TIG E T ++ + +M ++ L G A KR+ LA FG P S+Y + +R+Y +T A ESV E GS LL + I ++ GNL CIE++ G+ + Q + LHC+ F + + + R+ YQ + V+ + +E L + S + FR+ + +L LLD +DW+ L ++L + YL +F S SPT L+ LWE S + + A+ DL+ +L+ +GR D +LE
Sbjct: 341 IDSNGARLSLSKSGARLIVP--ELAVEGEKMLYLAVSDTLTDQPHLKPIESALSPVIVIGQCDVSMSAHDNILRRPVVVSFRHCASTFPRDNWQFTLYA-------DEGSG------WQKAVTIGEENLNTNMFVQFEQPGKKNDGFGWCHVMTYSLARLMLAGHPRRNSLSAAKRVHLAVFG-PTEMSAYRRPFELRVYCVPETGAAMESVWKQED--GSRLLCESNDFILNEK-GNLCICIEDVIPGFSCDGPEVVEISETQHRFVAQNG--LHCSLKFRPKEINGSQFSTRVIVYQKASSTEPMVMEVS---------------NEPELYDATSEEREKGSVCVEFRLPFGVKDELARLLDMPNESHSDWRGLAKKLHYDRYLQFFASFPDCSPTSLLLDLWEASSSGSARAVPDLLQTLRVMGRPDAVMVLE 740
BLAST of Netrin receptor UNC5B vs. Ensembl Celegans
Match: unc-5 (Netrin receptor unc-5 [Source:UniProtKB/Swiss-Prot;Acc:Q26261]) HSP 1 Score: 109.768 bits (273), Expect = 2.706e-24 Identity = 113/436 (25.92%), Postives = 179/436 (41.06%), Query Frame = 2
Query: 1808 ISTIGGRLCLPQSGITLTIAPGSFINSSSSEMYLAVSRNDPNPPILSDNETLLTPIVLFGPKDVP-------ILKPCVLSVPHSAD-LRQGNWVIRLLSCVLPDQNDELKEPLCQPIWKNIATIGCETDQTPIYTHL-------DPYA-AFIMLDQPQKICLVGQSYPGG-KATKRLRLAAFGRPLSTSSYLPNYNIRIYVFSDTKEAFESVSTIETKLGSTLLDITYQIIFSDSMGNLFFCIEELSTGWKSQLTTKYQEIPFQDIWSGSQSETLHCAFTFDNIDPSQQSLTCRITAYQSGFYNQKQVITIKQDKLDRSNHKRDLIQHEKVLLYSESNNTYLDPLMTVFRISNATRKKLCFLLDNVTPRGNDWKQLCRQLSLNGYLNYFMS--KVSPTDALVTLWE-SRNRNENALIDLIISLKAIGRTDCSTLLE 3055
I + G RL L +SG L + +YLAVS + P L E+ L+P+++ G DV + +P V+S H A + NW L + D+ W+ TIG E T ++ D + +M ++ L G A KR+ LA FG P S+Y + +R+Y +T A ESV E GS LL + I ++ GNL CIE++ G+ + Q + LHC+ F + + + R+ YQ + V+ + +E L + S + FR+ + +L LLD +DW+ L ++L + YL +F S SPT L+ LWE S + + A+ DL+ +L+ +GR D +LE
Sbjct: 246 IDSNGARLSLSKSGARLIVP--ELAVEGEKMLYLAVSDTLTDQPHLKPIESALSPVIVIGQCDVSMSAHDNILRRPVVVSFRHCASTFPRDNWQFTLYA----DEGSG---------WQKAVTIGEENLNTNMFVQFEQPGKKNDGFGWCHVMTYSLARLMLAGHPRRNSLSAAKRVHLAVFG-PTEMSAYRRPFELRVYCVPETGAAMESVWKQED--GSRLLCESNDFILNEK-GNLCICIEDVIPGFSCDGPEVVEISETQHRFVAQNG--LHCSLKFRPKEINGSQFSTRVIVYQKASSTEPMVMEV---------------SNEPELYDATSEEREKGSVCVEFRLPFGVKDELARLLDMPNESHSDWRGLAKKLHYDRYLQFFASFPDCSPTSLLLDLWEASSSGSARAVPDLLQTLRVMGRPDAVMVLE 645
BLAST of Netrin receptor UNC5B vs. Ensembl Fly
Match: unc-5 (gene:FBgn0034013 transcript:FBtr0339998) HSP 1 Score: 106.301 bits (264), Expect = 7.344e-23 Identity = 89/374 (23.80%), Postives = 166/374 (44.39%), Query Frame = 2
Query: 1946 SDNETLLTPIVLFGPKDVPILKPCVLSVPHSADLRQGNWVIRLLSCVLPDQNDELKEPLCQPIWKNIATIGCETDQTPIYTHLDPYAAFIMLDQPQKICLVGQSYPGGKATKRLRLAAFGRPLSTSSYLPNYNIRIYVFSDTKEAFESVSTIETKLGSTLLDITYQIIFSDSMGNLFFCIEELSTGWKSQLTTKYQE-IPFQDIWSGSQSETLHCAFTFDNIDPSQQSLTCRITAYQSGFYNQKQVITIKQDKLDRSNHKRDLIQHEKVLLYSESNNTYLDPLMTVFRISNATRKKLCFLLDNVTPRGNDWKQLCRQLSLNGYLNYFMSKVSPTDALVTLWESR---------NRNENALIDLIISLKAIGRTD 3037
+++ L + +V P++ +KP +L +PH + W + + ++DEL W+ ++G ET TP++ L+ FIM +Q +V + + K ++L AF + S+ N ++RIYV D + + + +E KLG + L + F+ + NL + + Y+ IP+Q I S + LHC F+ D Q SL + G + I + S + + + + + N +M ++ +AT++ +C LD DW+ L ++L+ + Y+ YF +K SPT+ ++ LWE R N + ++ L+++LK +GR D
Sbjct: 707 TESSILCSSVVHSAPRNYSFVKPVILKIPHCL-VAPEQWHVHIYHA--DSEHDELSVN-----WRRAVSVGEETINTPMFVQLEATHVFIMTEQLGHFTVVAEPRIQQPSIK-MKLLAFSQHTPPSN--ANCSLRIYVVKDFPNSRDICANVEAKLGGSFLGESQVFAFTLNSRNLNIRVRSADV----EAAAPYEHAIPYQHILS--NNSILHCEFSLRRQD--QNSLC---VDFGQGSEDDYYTFNIPAHSMSGSAEELASTTNTTISIDRQGNYVNESCVMDFVQLPHATKRLICGALDPPRADERDWRLLAKKLNTDRYIAYFATKASPTEQILNLWECRANSSPGSSSNSVSHTIMALLLTLKEMGRQD 1058 HSP 2 Score: 69.707 bits (169), Expect = 1.343e-11 Identity = 64/249 (25.70%), Postives = 101/249 (40.56%), Query Frame = 2
Query: 347 IPSFIKEPESVYYVYEKKPAKIVCIAEPVSHVNIICNKEVFSYMDLELSESNLRVRKMNKNNEDDLTNGHRWMFSLEITYNQVTEWFNT--FSCVCEAWNQIPSLRLAKKVHSRYGVIKEAYFKSNFKKVPQSKTVVKGQSLILTCVPPESKPKAQVQWMKNKKRLFENNRIKI-VEEHQLLIEDTLLTDSGNYSCIAISLEEKRYSPIAIVKIQESVTENPATQWSAWSACDGNCK----KTRTRNCN 1072
+P F+ EPESV+ V + +PA + C A V C S S+ ++ + D T + + I + V E+F F C C AW+ V S+ + AY + +F + P S + G L C PP P+ ++ W KN + ++ I V L+ L NYSC A ++ +R S A++ + + WS W C K + R+R CN
Sbjct: 127 LPIFLIEPESVFVV-KNRPAVLKCKASHSLQVIFKC------------SGSSQPPPSTHETHVDPHTGVNMEEVTATIHRDLVDEFFGDGPFKCECHAWSS------RGVVKSQAATVHIAYIRKSFNQSPTSLRLELGSRAELRCEPPGGFPEPKLTWHKNNAVITADSEPGITVSAGTLIFRQVALQHMANYSCSAENIAGRRVSDSAVLIV---YVNGGWSTWSPWRECKCAGKPSQGRKRSRTCN 353
BLAST of Netrin receptor UNC5B vs. Ensembl Fly
Match: unc-5 (gene:FBgn0034013 transcript:FBtr0087382) HSP 1 Score: 106.301 bits (264), Expect = 7.344e-23 Identity = 89/374 (23.80%), Postives = 166/374 (44.39%), Query Frame = 2
Query: 1946 SDNETLLTPIVLFGPKDVPILKPCVLSVPHSADLRQGNWVIRLLSCVLPDQNDELKEPLCQPIWKNIATIGCETDQTPIYTHLDPYAAFIMLDQPQKICLVGQSYPGGKATKRLRLAAFGRPLSTSSYLPNYNIRIYVFSDTKEAFESVSTIETKLGSTLLDITYQIIFSDSMGNLFFCIEELSTGWKSQLTTKYQE-IPFQDIWSGSQSETLHCAFTFDNIDPSQQSLTCRITAYQSGFYNQKQVITIKQDKLDRSNHKRDLIQHEKVLLYSESNNTYLDPLMTVFRISNATRKKLCFLLDNVTPRGNDWKQLCRQLSLNGYLNYFMSKVSPTDALVTLWESR---------NRNENALIDLIISLKAIGRTD 3037
+++ L + +V P++ +KP +L +PH + W + + ++DEL W+ ++G ET TP++ L+ FIM +Q +V + + K ++L AF + S+ N ++RIYV D + + + +E KLG + L + F+ + NL + + Y+ IP+Q I S + LHC F+ D Q SL + G + I + S + + + + + N +M ++ +AT++ +C LD DW+ L ++L+ + Y+ YF +K SPT+ ++ LWE R N + ++ L+++LK +GR D
Sbjct: 707 TESSILCSSVVHSAPRNYSFVKPVILKIPHCL-VAPEQWHVHIYHA--DSEHDELSVN-----WRRAVSVGEETINTPMFVQLEATHVFIMTEQLGHFTVVAEPRIQQPSIK-MKLLAFSQHTPPSN--ANCSLRIYVVKDFPNSRDICANVEAKLGGSFLGESQVFAFTLNSRNLNIRVRSADV----EAAAPYEHAIPYQHILS--NNSILHCEFSLRRQD--QNSLC---VDFGQGSEDDYYTFNIPAHSMSGSAEELASTTNTTISIDRQGNYVNESCVMDFVQLPHATKRLICGALDPPRADERDWRLLAKKLNTDRYIAYFATKASPTEQILNLWECRANSSPGSSSNSVSHTIMALLLTLKEMGRQD 1058 HSP 2 Score: 69.707 bits (169), Expect = 1.343e-11 Identity = 64/249 (25.70%), Postives = 101/249 (40.56%), Query Frame = 2
Query: 347 IPSFIKEPESVYYVYEKKPAKIVCIAEPVSHVNIICNKEVFSYMDLELSESNLRVRKMNKNNEDDLTNGHRWMFSLEITYNQVTEWFNT--FSCVCEAWNQIPSLRLAKKVHSRYGVIKEAYFKSNFKKVPQSKTVVKGQSLILTCVPPESKPKAQVQWMKNKKRLFENNRIKI-VEEHQLLIEDTLLTDSGNYSCIAISLEEKRYSPIAIVKIQESVTENPATQWSAWSACDGNCK----KTRTRNCN 1072
+P F+ EPESV+ V + +PA + C A V C S S+ ++ + D T + + I + V E+F F C C AW+ V S+ + AY + +F + P S + G L C PP P+ ++ W KN + ++ I V L+ L NYSC A ++ +R S A++ + + WS W C K + R+R CN
Sbjct: 127 LPIFLIEPESVFVV-KNRPAVLKCKASHSLQVIFKC------------SGSSQPPPSTHETHVDPHTGVNMEEVTATIHRDLVDEFFGDGPFKCECHAWSS------RGVVKSQAATVHIAYIRKSFNQSPTSLRLELGSRAELRCEPPGGFPEPKLTWHKNNAVITADSEPGITVSAGTLIFRQVALQHMANYSCSAENIAGRRVSDSAVLIV---YVNGGWSTWSPWRECKCAGKPSQGRKRSRTCN 353
BLAST of Netrin receptor UNC5B vs. Ensembl Fly
Match: robo2 (gene:FBgn0002543 transcript:FBtr0329985) HSP 1 Score: 67.0106 bits (162), Expect = 9.024e-11 Identity = 42/154 (27.27%), Postives = 72/154 (46.75%), Query Frame = 2
Query: 545 TNGHRWM------FSLEITYNQVTEWFNTFSCVCEAWNQIPSLRLAKKVHSRYGVIKEAYFKSNFKKVPQSKTVVKGQSLILTCVPPESKPKAQVQWMKNKK--RLFENNRIKIVEEHQLLIEDTLLTDSGNYSCIAISLEEKRYSPIAIVKIQ 982
T HR M F L++ +++ T+ CEA N+ R SR ++ A+ + F+ P + V +G+ ++ C P P+ Q+ W KN + L N RI+IV+ L I++ +D G Y C+ ++ R S A +K+
Sbjct: 135 TGSHRIMLPAGGLFFLKVIHSRRESDAGTY--WCEAKNEFGVAR------SRNATLQVAFLRDEFRLEPANTRVAQGEVALMECGAPRGSPEPQISWRKNGQTLNLVGNKRIRIVDGGNLAIQEARQSDDGRYQCVVKNVVGTRESATAFLKVH 280
BLAST of Netrin receptor UNC5B vs. Ensembl Fly
Match: robo2 (gene:FBgn0002543 transcript:FBtr0077941) HSP 1 Score: 67.0106 bits (162), Expect = 9.024e-11 Identity = 42/154 (27.27%), Postives = 72/154 (46.75%), Query Frame = 2
Query: 545 TNGHRWM------FSLEITYNQVTEWFNTFSCVCEAWNQIPSLRLAKKVHSRYGVIKEAYFKSNFKKVPQSKTVVKGQSLILTCVPPESKPKAQVQWMKNKK--RLFENNRIKIVEEHQLLIEDTLLTDSGNYSCIAISLEEKRYSPIAIVKIQ 982
T HR M F L++ +++ T+ CEA N+ R SR ++ A+ + F+ P + V +G+ ++ C P P+ Q+ W KN + L N RI+IV+ L I++ +D G Y C+ ++ R S A +K+
Sbjct: 135 TGSHRIMLPAGGLFFLKVIHSRRESDAGTY--WCEAKNEFGVAR------SRNATLQVAFLRDEFRLEPANTRVAQGEVALMECGAPRGSPEPQISWRKNGQTLNLVGNKRIRIVDGGNLAIQEARQSDDGRYQCVVKNVVGTRESATAFLKVH 280
BLAST of Netrin receptor UNC5B vs. Ensembl Fly
Match: robo3 (gene:FBgn0041097 transcript:FBtr0077921) HSP 1 Score: 65.855 bits (159), Expect = 2.010e-10 Identity = 38/121 (31.40%), Postives = 61/121 (50.41%), Query Frame = 2
Query: 626 CEAWNQIPSLRLAKKVHSRYGVIKEAYFKSNFKKVPQSKTVVKGQSLILTCVPPESKPKAQVQWMKNKKRL-FENN-RIKIVEEHQLLIEDTLLTDSGNYSCIAISLEEKRYSPIAIVKIQ 982
CEA N++ R SR ++ A + F+ PQ+ + +G + +L C P P+ V W K ++L E + R++IV+ L I+D TD G Y CIA + R S +A +K+
Sbjct: 98 CEAKNELGVAR------SRNATLQVAVLRDEFRLEPQNTRIAQGDTALLECAAPRGIPEPTVTWKKGGQKLDLEGSKRVRIVDGGNLAIQDARQTDEGQYQCIAKNPVGVRESSLATLKVH 212
BLAST of Netrin receptor UNC5B vs. Ensembl Zebrafish
Match: UNC5C (si:ch73-72b7.1 [Source:ZFIN;Acc:ZDB-GENE-100921-23]) HSP 1 Score: 251.136 bits (640), Expect = 6.451e-70 Identity = 228/891 (25.59%), Postives = 381/891 (42.76%), Query Frame = 2
Query: 572 LEITYNQVTEWFN--TFSCVCEAWNQIPSLRLAKKVHSRYGVIKEAYFKSNFKKVPQSKTVVKGQSLILTCVPPESKPKAQVQWMKNKKRL--FENNRIKIVEEHQLLIEDTLLTDSGNYSCIAISLEEKRYSPIAIVKI-------------------------QESVTENPA----------------------------TQWSAWSACDGNCKKTRTRNCNS----------KGVCKEIDSCTKKECEYNRAVAPFVKNPNKNGVSTSSLQDARDIAMYVGLFVAVTILVMVITIIFCLIRRKALLPLRSTMRYPLNINGNGVAYDVKNSLIKNSNTISTKNPYIMDTSLANLTQQRSYLSQSPPNLPPPTCLSEISSTNAYSTGIDFSYNSTGSGKFSQPLIXXXXXXXXXXXXXXXXXXXXDHKPDPLTVSGTPINSRPPSALYHELSLDRESICNSPPFVSENIDISTLAWGTISTIGGRLCLPQSGITLTIAPGSFINSSSSEMYLAVSRNDPNPPILSDNETLLTPIVLFGPKDVPILKPCVLSVPHSADLRQGNWVIRLLSCVLPDQNDELKEPLCQPIWKNIATIGCETDQTPIYTHLDPYAAFIMLDQPQKICLVGQSYPGGKATKRLRLAAFGRPLSTSSYLPNYNIRIYVFSDTKEAFESVSTIETKLGSTLLDITYQIIFSDSMGNLFFCIEELSTGWKSQLTTKYQEIPFQDIWSGSQSETLHCAFTFDNIDPSQQSLTCRITAYQSGFYNQKQVITIKQDKLDRSNHKRDLIQHEKVLLYSESNNTYLDPLMTVFRISNATRKKLCFLLDNVTPRGNDWKQLCRQLSLNGYLNYFMSKVSPTDALVTLWESRNRNENALIDLIISLKAIGRTDCS 3043
+EI+ QV E F + C C AW+ + + ++KVH R I F + P S Q+++L C V+W+KN++ + ++ I +H L+I+ L+D+ NY+C+A ++ KR S A V + + NPA WS WSAC+ +C + R R CNS G+ + +CT C + F+ V +++ ++A+YVG+ +AV + ++V I+ L+ R+ S + +NG +K + S + P + +S A L + Y + P T + + I YN++G+ ++ D L+ + +P + H L LD + + + D + A G+ +++GG L +P SG++L + G+ EMY+++ R + P +++ E +L+ +V GP + +P +L++ H A NW I L S DQ W+++ +G E T Y L A I+ + L+GQS A KR++LA FG P+ T +Y+IR+Y DT++ + V IE ++G LLD + F+ S NL + ++ W+S+L TKYQE+ F +WSGS LHC+FT + S +C++ Q + Q+ + S D+ + L+ S+ T L + FRI + R KLC LD RGNDW++L +L L+ YLNYF +K SPT ++ LWE+++ L L L+ +GR D S
Sbjct: 7 IEISRQQVEELFGLEDYWCQCVAWSSAGTTK-SRKVHVR---IACELFGN-----PWSTE----QTIVLQCF---------VEWLKNEEIIDPADDRNFYITIDHNLIIKQARLSDTANYTCVAKNIVAKRRSTTATVIVYVNGGWSTWTEWSPCNSRCGRGLQKRTRSCTNPAPLNGGSPCDGQAIQKIACTSVCTVDGEWADWSRWSACNTDCTQWRKRECNSPAPQNGGKDCDGLTLQSQNCTDGLCLQMLFIYSFIY------VCSAAAPGGDEVALYVGIIMAVLMCLIVSAIVALLVYRRTHRRFHSDIIDSSVLNGGFQPVSIKQA---RSADLLAATPDL--SSAAALYRGPVYALHDISDKIPMTSSPLLEPLPLPNLKIKV-YNTSGT------------------------VTPQDDLTSDLSATLSP-------KVTHSL-LDGDPMTPRTQTLMRTRDPTCTALGSFNSLGGHLIIPNSGVSLLVPAGAIPQGRVYEMYVSLQRTESMRPPVAEGEAVLSAVVSCGPAGALLTRPVILTLHHCAHAHADNWRIILKSHTQHDQ------------WEDVVVVGEENFTTACYVQLGEEACHILTETLGSYSLIGQSI-CQSAAKRIKLAVFG-PVVTPGL--DYHIRVYCLDDTEDTLKEVLQIEKQMGGKLLDEPKSLNFTYSNHNLRLSVHDIHCQWRSKLLTKYQEVLFSQVWSGS-VRRLHCSFTLERQALSVCEFSCKLCVRQ--VEGEGQIFQLY------STLSEDVQSIDTSLMDPGSSITVLSG-PSAFRIPVSIRNKLCSSLDAPHTRGNDWRKLAHKLQLDRYLNYFATKTSPTGVILDLWEAQHFPHGNLNQLATVLEEMGRHDHS 805
BLAST of Netrin receptor UNC5B vs. Ensembl Zebrafish
Match: unc5b (unc-5 netrin receptor B [Source:ZFIN;Acc:ZDB-GENE-041213-1]) HSP 1 Score: 224.557 bits (571), Expect = 2.619e-60 Identity = 135/423 (31.91%), Postives = 221/423 (52.25%), Query Frame = 2
Query: 1796 AWGTISTIGGRLCLPQSGITLTIAPGSFINSSSSEMYLAVSRNDPNPPILSDNETLLTPIVLFGPKDVPILKPCVLSVPHSADLRQGNWVIRLLSCVLPDQNDELKEPLCQPIWKNIATIGCETDQTPIYTHLDPYAAFIMLDQPQKICLVGQSYPGGKATKRLRLAAFGRPLSTSSYLPNYNIRIYVFSDTKEAFESVSTIETKLGSTLLDITYQIIFSDSMGNLFFCIEEL-STGWKSQLTTKYQEIPFQDIWSGSQSETLHCAFTFDNIDPSQQSLTCRITAYQSGFYNQKQVITIKQDKLDRSNHKRDLIQHEKVLLYSESNNTYLDPLMTVFRISNATRKKLCFLLDNVTPRGNDWKQLCRQLSLNGYLNYFMSKVSPTDALVTLWESRNRNENALIDLIISLKAIGRTDCSTLLESD 3061
A T+ ++GGRL +P +G++L + PG+ EMYL +++ + ++T+L+P+V GP + + +P VL++PH A L +W + L QN Q W+ + T+G E+ +P Y ++ + I+++Q LVGQS P A KRL+LA F P + L +Y++R+Y DT A + V +E LG LL+ ++F DS N+ I ++ + W+S+L KYQEIPF IWSGSQ LHC F+ + LTC+I Q + Q+ + D + + + L S Y FR+ + R+K+C LD + RG DW+ L R L+ + YLNYF +K SPT L+ LWE+ ++ + L+ L +L+ +G+++ ++ +D
Sbjct: 510 ASATLGSLGGRLTIPNTGVSLLVPPGTIPQGKFYEMYLIINKWEKTTLPSDGSQTVLSPVVSCGPSGMLLSRPVVLTLPHCAQLEPPDWTL-----TLKMQNH-------QGAWEEVLTVGEESLSSPCYLQVEEQSCHILMEQLGTYGLVGQSAPPRPACKRLQLALFA-PRAPCLSL-DYSLRVYCIQDTPHALKEVLEVERSLGGVLLEDPKPLLFKDSYHNMRLSIHDIPHSHWRSKLLAKYQEIPFYHIWSGSQ-RPLHCTFSLERGSLVVSQLTCKICVRQ--VEGEGQIFQLNTD-IQETLPPHSPLPAGGSCLPSSQVGPY------AFRLPVSIRQKICASLDAPSARGCDWRMLARSLAFDRYLNYFATKPSPTGVLLDLWEACHQGDADLVSLATALEEMGKSEVLVVMTTD 908 HSP 2 Score: 114.39 bits (285), Expect = 2.550e-25 Identity = 74/252 (29.37%), Postives = 121/252 (48.02%), Query Frame = 2
Query: 341 EGIPSFIKEPESVYYVYEKKPAKIVCIAEPVSHVNIICNKEVFSYMDLELSESNLRVRKMNKNNEDDLTNGHRWMFSLEITYNQVTEWFN--TFSCVCEAWNQIPSLRLAKKVHSRYGVIKEAYFKSNFKKVPQSKTVVKGQSLILTCVPPESKPKAQVQWMKNKKRL---FENNRIKIVEEHQLLIEDTLLTDSGNYSCIAISLEEKRYSPIAIVKIQESVTENPATQWSAWSACDGNCKKT---RTRNCN 1072
E +P F EPE + V + +P K+ C A P + + CN E + D + K + D +T + ++ QV E F + C C AW+ A SR ++ AY + NF++ P + V Q ++L C PPE P A+V W+KN++ + ++N + I EH L+I+ L+D+ NY+C+A ++ KR S A + + S + W+ WS C+ C + RTR+C
Sbjct: 19 EPLPEFQSEPEDAFIV-KNRPVKLSCKAAPATQIYFKCNGEWVNQND-----------HVTKESLDHITGLVVREVDISVSRTQVEELFGLEDYWCQCVAWSS------AGTTKSRRAYVRIAYLRKNFEQEPLGREVRLEQEVLLQCRPPEGSPPAEVDWLKNEELIDPALDSNFL-ITIEHDLIIKQARLSDTANYTCVARNVVAKRRSSTATLIVYVS---GGWSSWTEWSECNAQCGRGWQRRTRSCT 248
BLAST of Netrin receptor UNC5B vs. Ensembl Zebrafish
Match: unc5b (unc-5 netrin receptor B [Source:ZFIN;Acc:ZDB-GENE-041213-1]) HSP 1 Score: 224.557 bits (571), Expect = 2.723e-60 Identity = 135/423 (31.91%), Postives = 221/423 (52.25%), Query Frame = 2
Query: 1796 AWGTISTIGGRLCLPQSGITLTIAPGSFINSSSSEMYLAVSRNDPNPPILSDNETLLTPIVLFGPKDVPILKPCVLSVPHSADLRQGNWVIRLLSCVLPDQNDELKEPLCQPIWKNIATIGCETDQTPIYTHLDPYAAFIMLDQPQKICLVGQSYPGGKATKRLRLAAFGRPLSTSSYLPNYNIRIYVFSDTKEAFESVSTIETKLGSTLLDITYQIIFSDSMGNLFFCIEEL-STGWKSQLTTKYQEIPFQDIWSGSQSETLHCAFTFDNIDPSQQSLTCRITAYQSGFYNQKQVITIKQDKLDRSNHKRDLIQHEKVLLYSESNNTYLDPLMTVFRISNATRKKLCFLLDNVTPRGNDWKQLCRQLSLNGYLNYFMSKVSPTDALVTLWESRNRNENALIDLIISLKAIGRTDCSTLLESD 3061
A T+ ++GGRL +P +G++L + PG+ EMYL +++ + ++T+L+P+V GP + + +P VL++PH A L +W + L QN Q W+ + T+G E+ +P Y ++ + I+++Q LVGQS P A KRL+LA F P + L +Y++R+Y DT A + V +E LG LL+ ++F DS N+ I ++ + W+S+L KYQEIPF IWSGSQ LHC F+ + LTC+I Q + Q+ + D + + + L S Y FR+ + R+K+C LD + RG DW+ L R L+ + YLNYF +K SPT L+ LWE+ ++ + L+ L +L+ +G+++ ++ +D
Sbjct: 539 ASATLGSLGGRLTIPNTGVSLLVPPGTIPQGKFYEMYLIINKWEKTTLPSDGSQTVLSPVVSCGPSGMLLSRPVVLTLPHCAQLEPPDWTL-----TLKMQNH-------QGAWEEVLTVGEESLSSPCYLQVEEQSCHILMEQLGTYGLVGQSAPPRPACKRLQLALFA-PRAPCLSL-DYSLRVYCIQDTPHALKEVLEVERSLGGVLLEDPKPLLFKDSYHNMRLSIHDIPHSHWRSKLLAKYQEIPFYHIWSGSQ-RPLHCTFSLERGSLVVSQLTCKICVRQ--VEGEGQIFQLNTD-IQETLPPHSPLPAGGSCLPSSQVGPY------AFRLPVSIRQKICASLDAPSARGCDWRMLARSLAFDRYLNYFATKPSPTGVLLDLWEACHQGDADLVSLATALEEMGKSEVLVVMTTD 937 HSP 2 Score: 114.775 bits (286), Expect = 2.227e-25 Identity = 74/252 (29.37%), Postives = 121/252 (48.02%), Query Frame = 2
Query: 341 EGIPSFIKEPESVYYVYEKKPAKIVCIAEPVSHVNIICNKEVFSYMDLELSESNLRVRKMNKNNEDDLTNGHRWMFSLEITYNQVTEWFN--TFSCVCEAWNQIPSLRLAKKVHSRYGVIKEAYFKSNFKKVPQSKTVVKGQSLILTCVPPESKPKAQVQWMKNKKRL---FENNRIKIVEEHQLLIEDTLLTDSGNYSCIAISLEEKRYSPIAIVKIQESVTENPATQWSAWSACDGNCKKT---RTRNCN 1072
E +P F EPE + V + +P K+ C A P + + CN E + D + K + D +T + ++ QV E F + C C AW+ A SR ++ AY + NF++ P + V Q ++L C PPE P A+V W+KN++ + ++N + I EH L+I+ L+D+ NY+C+A ++ KR S A + + S + W+ WS C+ C + RTR+C
Sbjct: 48 EPLPEFQSEPEDAFIV-KNRPVKLSCKAAPATQIYFKCNGEWVNQND-----------HVTKESLDHITGLVVREVDISVSRTQVEELFGLEDYWCQCVAWSS------AGTTKSRRAYVRIAYLRKNFEQEPLGREVRLEQEVLLQCRPPEGSPPAEVDWLKNEELIDPALDSNFL-ITIEHDLIIKQARLSDTANYTCVARNVVAKRRSSTATLIVYVS---GGWSSWTEWSECNAQCGRGWQRRTRSCT 277
BLAST of Netrin receptor UNC5B vs. Ensembl Zebrafish
Match: unc5b (unc-5 netrin receptor B [Source:ZFIN;Acc:ZDB-GENE-041213-1]) HSP 1 Score: 224.172 bits (570), Expect = 3.446e-60 Identity = 135/423 (31.91%), Postives = 221/423 (52.25%), Query Frame = 2
Query: 1796 AWGTISTIGGRLCLPQSGITLTIAPGSFINSSSSEMYLAVSRNDPNPPILSDNETLLTPIVLFGPKDVPILKPCVLSVPHSADLRQGNWVIRLLSCVLPDQNDELKEPLCQPIWKNIATIGCETDQTPIYTHLDPYAAFIMLDQPQKICLVGQSYPGGKATKRLRLAAFGRPLSTSSYLPNYNIRIYVFSDTKEAFESVSTIETKLGSTLLDITYQIIFSDSMGNLFFCIEEL-STGWKSQLTTKYQEIPFQDIWSGSQSETLHCAFTFDNIDPSQQSLTCRITAYQSGFYNQKQVITIKQDKLDRSNHKRDLIQHEKVLLYSESNNTYLDPLMTVFRISNATRKKLCFLLDNVTPRGNDWKQLCRQLSLNGYLNYFMSKVSPTDALVTLWESRNRNENALIDLIISLKAIGRTDCSTLLESD 3061
A T+ ++GGRL +P +G++L + PG+ EMYL +++ + ++T+L+P+V GP + + +P VL++PH A L +W + L QN Q W+ + T+G E+ +P Y ++ + I+++Q LVGQS P A KRL+LA F P + L +Y++R+Y DT A + V +E LG LL+ ++F DS N+ I ++ + W+S+L KYQEIPF IWSGSQ LHC F+ + LTC+I Q + Q+ + D + + + L S Y FR+ + R+K+C LD + RG DW+ L R L+ + YLNYF +K SPT L+ LWE+ ++ + L+ L +L+ +G+++ ++ +D
Sbjct: 528 ASATLGSLGGRLTIPNTGVSLLVPPGTIPQGKFYEMYLIINKWEKTTLPSDGSQTVLSPVVSCGPSGMLLSRPVVLTLPHCAQLEPPDWTL-----TLKMQNH-------QGAWEEVLTVGEESLSSPCYLQVEEQSCHILMEQLGTYGLVGQSAPPRPACKRLQLALFA-PRAPCLSL-DYSLRVYCIQDTPHALKEVLEVERSLGGVLLEDPKPLLFKDSYHNMRLSIHDIPHSHWRSKLLAKYQEIPFYHIWSGSQ-RPLHCTFSLERGSLVVSQLTCKICVRQ--VEGEGQIFQLNTD-IQETLPPHSPLPAGGSCLPSSQVGPY------AFRLPVSIRQKICASLDAPSARGCDWRMLARSLAFDRYLNYFATKPSPTGVLLDLWEACHQGDADLVSLATALEEMGKSEVLVVMTTD 926 HSP 2 Score: 114.775 bits (286), Expect = 2.034e-25 Identity = 74/252 (29.37%), Postives = 121/252 (48.02%), Query Frame = 2
Query: 341 EGIPSFIKEPESVYYVYEKKPAKIVCIAEPVSHVNIICNKEVFSYMDLELSESNLRVRKMNKNNEDDLTNGHRWMFSLEITYNQVTEWFN--TFSCVCEAWNQIPSLRLAKKVHSRYGVIKEAYFKSNFKKVPQSKTVVKGQSLILTCVPPESKPKAQVQWMKNKKRL---FENNRIKIVEEHQLLIEDTLLTDSGNYSCIAISLEEKRYSPIAIVKIQESVTENPATQWSAWSACDGNCKKT---RTRNCN 1072
E +P F EPE + V + +P K+ C A P + + CN E + D + K + D +T + ++ QV E F + C C AW+ A SR ++ AY + NF++ P + V Q ++L C PPE P A+V W+KN++ + ++N + I EH L+I+ L+D+ NY+C+A ++ KR S A + + S + W+ WS C+ C + RTR+C
Sbjct: 48 EPLPEFQSEPEDAFIV-KNRPVKLSCKAAPATQIYFKCNGEWVNQND-----------HVTKESLDHITGLVVREVDISVSRTQVEELFGLEDYWCQCVAWSS------AGTTKSRRAYVRIAYLRKNFEQEPLGREVRLEQEVLLQCRPPEGSPPAEVDWLKNEELIDPALDSNFL-ITIEHDLIIKQARLSDTANYTCVARNVVAKRRSSTATLIVYVS---GGWSSWTEWSECNAQCGRGWQRRTRSCT 277
BLAST of Netrin receptor UNC5B vs. Ensembl Zebrafish
Match: unc5a (unc-5 netrin receptor A [Source:ZFIN;Acc:ZDB-GENE-080219-19]) HSP 1 Score: 207.223 bits (526), Expect = 8.358e-55 Identity = 134/423 (31.68%), Postives = 214/423 (50.59%), Query Frame = 2
Query: 1796 AWGTISTIGGRLCLPQSGITLTIAPGSFINSSSSEMYLAVSRNDPNPPILSDNETLLTPIVLFGPKDVPILKPCVLSVPHSADLRQGNWVIRLLSCVLPDQNDELKEPLCQPIWKNIATIGCETDQTPIYTHLDPYAAFIMLDQPQKICLVGQSYPGGKATKRLRLAAFGRPLSTSSYLPNYNIRIYVFSDTKEAFESVSTIETKLGSTLLDITYQIIFSDSMGNLFFCIEEL-STGWKSQLTTKYQEIPFQDIWSGSQSETLHCAFTFDNIDPSQQSLTCRITAYQSGFYNQKQVITIKQDKLDRSNHKRDLIQHEKVLLYSESNNTYLDPLMTVFRISNATRKKLCFLLDNVTPRGNDWKQLCRQLSLNGYLNYFMSKVSPTDALVTLWESRNRNENALIDLIISLKAIGRTDCSTLLESD 3061
++GT + +GGRL LP +GI+L I P + E+YL + + + L+ +TLL+P+V GP V + +P +L + H +D NW IR LK+ + W+++ +G + P Y L+ + +Q + LVG+S A KRL+L F P S+ YNIR+Y DT++ + V +E +LG L+D + ++F DS NL I ++ T W+S+L YQEIPF IWSGSQ TLHC+FT + S L+C + +Q Q + N +D+ + L E+ + L + F+I R+K+C LD P G DW+ L ++L L+ ++++F SK SPT ++ LWE+++ + L L + IG+ + L SD
Sbjct: 461 SYGTFNFLGGRLTLPNTGISLLIPPEAIPRGKIYEIYLTIQKKEDMRLPLAGCQTLLSPVVSCGPPGVMLTRPVILCMDHCSDACLENWAIR------------LKKQSYEGTWEDVLLLGEDLLSEPYYCQLEAETCRVFTEQLGRFALVGESL-SMAAAKRLKLLLFA-PAYCSTL--EYNIRVYCTDDTQDLLKEVMQMERQLGGRLIDEPHVLLFKDSYHNLRLSIHDMPHTHWRSKLLAGYQEIPFYHIWSGSQ-RTLHCSFTLERQSLSTSDLSCTLCVWQVEGEGQSFSLDF--------NIAKDIRPLDSDFLLLENCSPALAG-PSAFQIPYLIRQKICSSLDAPCPNGADWRLLAQRLKLDRHMSFFASKSSPTSVILDLWETQHFHSGNLNQLAAVMAEIGKQEAMIFLVSD 857 HSP 2 Score: 120.553 bits (301), Expect = 2.910e-27 Identity = 87/328 (26.52%), Postives = 153/328 (46.65%), Query Frame = 2
Query: 347 IPSFIKEPESVYYVYEKKPAKIVCIAEPVSHVNIICNKEVFSYMDLELSESNLRVRKMNKNNEDDLTNGHRWMFSLEITYNQVTEWFN--TFSCVCEAWNQIPSLRLAKKVHSRYGVIKEAYFKSNFKKVPQSKTVVKGQSLILTCVPPESKPKAQVQWMKNKKRL--FENNRIKIVEEHQLLIEDTLLTDSGNYSCIAISLEEKRYSPIAIVKIQESVTENPATQWSAWSACDGNCKKTRTRNCN--SKGV----CKEID----SCTKKECEYNRAVAPFVKNPNKNGVSTSSLQDARDIAMYVGLFVAVTILVMVITIIFCLIRRK 1288
+P F+ EP+ VY V + KP + C + P + + CN E + + D L + ++ D T ++I+ QV + F + C C AW+ + + S+ ++ AY + NF++ P K V Q L+L C PPE P A+V+W +N++ + + I +H L+I+ T L D+GNY+C+A ++ +R S A V + + ++WS WS C +C R+R C + G C+ +D +CT ++C + A D+A+YVG+ L +++ ++ + RRK
Sbjct: 51 LPHFLIEPDDVYIV-KNKPVTLTCRSTPATQIYFKCNGE-WVHQDQHLIDRDV----------DPATGLPVMQVKIDISRQQVEKIFGLEDYWCQCVAWSTTGTQK------SQKAFVRIAYLRKNFEEEPLGKEVALDQELLLRCHPPEGVPPAEVEWQRNEELIDPKTDPNFFITTDHNLIIKQTRLADTGNYTCVAKNIVARRKSSSATVIV---YVDGGWSEWSKWSPCGADCSMWRSRECTQPTPGTGGKDCQGLDLQSLNCTSEQCP-------------------QTASGAEDVALYVGMVTVALCLALLLVVLVLVYRRK 338
BLAST of Netrin receptor UNC5B vs. Ensembl Xenopus
Match: ndufaf7 (NADH:ubiquinone oxidoreductase complex assembly factor 7 [Source:Xenbase;Acc:XB-GENE-996599]) HSP 1 Score: 310.457 bits (794), Expect = 3.259e-90 Identity = 275/984 (27.95%), Postives = 425/984 (43.19%), Query Frame = 2
Query: 296 IEDENDFVKLNES----KLEGIPSFIKEPESVYYVYEKKPAKIVCIAEPVSHVNIICNKEVFSYMDLELSE-----SNLRVRKMNKNNEDDLTNGHRWMFSLEITYNQVTEWFN--TFSCVCEAWNQIPSLRLAKKVHSRYGVIKEAYFKSNFKKVPQSKTVVKGQSLILTCVPPESKPKAQVQWMKNKKRL--FENNRIKIVEEHQLLIEDTLLTDSGNYSCIAISLEEKRYSPIAIVKI-------------------------QESVTENPA----------------------------TQWSAWSACDGNCKKTRTRNCNSKGVCKEIDSCTKKECEYNRAVAPFVKNPNKNGVSTSSLQDARDIAMYVGLFVAVTILVMVITIIFCLIRRKALLPLRSTMRYPLNINGNGVAYDVKNSLIKNSNTISTKNPYIMDTSLANLTQQRSYLSQSPPNLPPPTCLSEISSTNAYSTGIDFSYNSTGSGKF---SQPLIXXXXXXXXXXXXXXXXXXXXDHKPDPLTVSGTPINSRPPSALYHELSLDRESICNSPPFVSENIDISTLAWGTISTIGGRLCLPQSGITLTIAPGSFINSSSSEMYLAVSRNDPNPPILSDNETLLTPIVLFGPKDVPILKPCVLSVPHSADLRQGNWVIRLLSCVLPDQNDELKEPLCQPIWKNIATIGCETDQTPIYTHLDPYAAFIMLDQPQKICLVGQSYPGGKATKRLRLAAFGRPLSTSSYLPNYNIRIYVFSDTKEAFESVSTIETKLGSTLLDITYQIIFSDSMGNLFFCIEEL-STGWKSQLTTKYQEIPFQDIWSGSQSETLHCAFTFDNIDPSQQSLTCRITAYQSGFYNQKQVITIKQDKLDRSNHKRDLIQHEKVLLYSESNNTYLDPLMTVFRISNATRKKLCFLLDNVTPRGNDWKQLCRQLSLNGYLNYFMSKVSPTDALVTLWESRNRNENALIDLIISLKAIGRTD 3037
+ D++ F +L E+ E +P F+ EPE Y V + KP + C A P + + CN E D ++E S L VR++ S+EI+ QV E F + C C AW+ A SR ++ AY + F++ P K V Q ++L C PPE P A+V+W+KN+ + E+ I +H L+I+ L+D+ NY+C+A ++ KR S A V + + NPA T WS WS C C R R+C + K+C+ P +++ N + + + V L+V + I V+V I ++ AL R N G D+ ++ N + N+ R L PP+L +S A G ++ + S K + PL+ + + + +++ D D S+ S + L L+ +++ ++ D S A+GT +++GG L +P SG++L I G+ EMY+ V R + P + D++TLLTP+V GP + +P +L++ H A+ +W + +LKE Q W+++ +G E TP Y ++ A I+ + LVGQS A KRL+LA FG P S +S YNIR+Y DT++A + V E K+G LLD + F S NL I ++ + WKS+L KYQEIPF IWSG Q LHC FT + S L C++ Q + Q+ +L+ S H R H K S + T + P + F I R+KLC LD RG+DW+ L +L L+ YLNYF +K SPT ++ LWE++N E L L L+ +GR +
Sbjct: 8 VADDDFFHELPETFPSDPPEPLPHFLIEPEEAYIV-KNKPVNLYCKASPATQIYFKCNSEWVHQKDHVVNEKVDETSGLIVREV----------------SIEISRQQVEELFGLEDYWCQCVAWSS------AGTTKSRKAYVRIAYLRKTFEQEPLGKEVSLEQEVLLQCRPPEGIPGAEVEWLKNEDVIDPVEDRNFYITIDHNLIIKQARLSDTANYTCVAKNIVGKRRSTTATVIVYVNGGWSTWTEWSACSNRCGKGYQKRTRTCTNPAPLNGGYICEGQGVQKMACTSLCPEDGEWTAWSKWSTCGTECTHWRRRDCANPP-----PRNGGKDCD-----GPVLQSKNCTDGLCMQVYKSHRLENNVALYVGIVIAVIVCLAISVIV---ALFVYRK--------NHRGFESDIIDTSALNGGFQA-----------VNIKAARQDLLGVPPDL---------TSAAAMYRGPVYALHDV-SDKIPMTNSPLLDPLPNLKIKVYNSSGTVTPQDDLSD--------YTSKLSSQITQSL-LENDTLNMKNQSLARQTDPSCTAFGTFNSLGGHLIIPNSGVSLLIPAGAVPQGRVYEMYVTVHRKENMRPPIEDSQTLLTPVVSCGPPGALMTRPVILTMHHCAETTGEDWKM------------QLKEQSVQGQWEDVVFVGEENFTTPCYIQMESEACHILTETLSTYALVGQSTSKSSA-KRLKLALFG-PTSCTSL--EYNIRVYCLDDTQDALKEVIQQERKVGGQLLDEPKTLHFKGSTHNLRLSIHDVPHSLWKSKLLAKYQEIPFYHIWSGCQ-RNLHCTFTLERFSLSTVELVCKLCVRQ--VEGEGQIF-----QLNFSWHLR-FCSHTK----SSTITTIVGP--SAFSIPLTIRQKLCSSLDAPQTRGHDWRMLAHKLKLDRYLNYFATKPSPTGVILDLWEAQNYPEGNLSTLAAVLEEMGRHE 886
BLAST of Netrin receptor UNC5B vs. Ensembl Xenopus
Match: ndufaf7 (NADH:ubiquinone oxidoreductase complex assembly factor 7 [Source:Xenbase;Acc:XB-GENE-996599]) HSP 1 Score: 306.605 bits (784), Expect = 1.060e-88 Identity = 277/989 (28.01%), Postives = 428/989 (43.28%), Query Frame = 2
Query: 296 IEDENDFVKLNES----KLEGIPSFIKEPESVYYVYEKKPAKIVCIAEPVSHVNIICNKEVFSYMDLELSE-----SNLRVRKMNKNNEDDLTNGHRWMFSLEITYNQVTEWFN--TFSCVCEAWNQIPSLRLAKKVHSRYGVIKEAYFKSNFKKVPQSKTVVKGQSLILTCVPPESKPKAQVQWMKNKKRL--FENNRIKIVEEHQLLIEDTLLTDSGNYSCIAISLEEKRYSPIAIVKI-------------------------QESVTENPA----------------------------TQWSAWSACDGNCKKTRTRNCNSKGVCKEIDSCTKKECEYNRAVAPFVKNPN-KNGVS---TSSLQDARDIAMY-VGLFVAVTILVMVITIIFCLIRRKALLPLRSTMRYPLNINGNGVAYDVKNSLIKNSNTISTKNPYIMDTSLANLTQQRSYLSQSPPNLPPPTCLSEISSTNAYSTGIDFSYNSTGSGKF---SQPLIXXXXXXXXXXXXXXXXXXXXDHKPDPLTVSGTPINSRPPSALYHELSLDRESICNSPPFVSENIDISTLAWGTISTIGGRLCLPQSGITLTIAPGSFINSSSSEMYLAVSRNDPNPPILSDNETLLTPIVLFGPKDVPILKPCVLSVPHSADLRQGNWVIRLLSCVLPDQNDELKEPLCQPIWKNIATIGCETDQTPIYTHLDPYAAFIMLDQPQKICLVGQSYPGGKATKRLRLAAFGRPLSTSSYLPNYNIRIYVFSDTKEAFESVSTIETKLGSTLLDITYQIIFSDSMGNLFFCIEEL-STGWKSQLTTKYQEIPFQDIWSGSQSETLHCAFTFDNIDPSQQSLTCRITAYQSGFYNQKQVITIKQDKLDRSNHKRDLIQHEKVLLYSESNNTYLDPLMTVFRISNATRKKLCFLLDNVTPRGNDWKQLCRQLSLNGYLNYFMSKVSPTDALVTLWESRNRNENALIDLIISLKAIGRTD 3037
+ D++ F +L E+ E +P F+ EPE Y V + KP + C A P + + CN E D ++E S L VR++ S+EI+ QV E F + C C AW+ A SR ++ AY + F++ P K V Q ++L C PPE P A+V+W+KN+ + E+ I +H L+I+ L+D+ NY+C+A ++ KR S A V + + NPA T WS WS C C R R+C + K+C+ P +++ N +G+ + SL R +Y V L+V + I V+V I ++ AL R N G D+ ++ N + N+ R L PP+L +S A G ++ + S K + PL+ + + + +++ D D S+ S + L L+ +++ ++ D S A+GT +++GG L +P SG++L I G+ EMY+ V R + P + D++TLLTP+V GP + +P +L++ H A+ +W + +LKE Q W+++ +G E TP Y ++ A I+ + LVGQS A KRL+LA FG P S +S YNIR+Y DT++A + V E K+G LLD + F S NL I ++ + WKS+L KYQEIPF IWSG Q LHC FT + S L C++ Q Q I Q + DL ++ + + T + P + F I R+KLC LD RG+DW+ L +L L+ YLNYF +K SPT ++ LWE++N E L L L+ +GR +
Sbjct: 8 VADDDFFHELPETFPSDPPEPLPHFLIEPEEAYIV-KNKPVNLYCKASPATQIYFKCNSEWVHQKDHVVNEKVDETSGLIVREV----------------SIEISRQQVEELFGLEDYWCQCVAWSS------AGTTKSRKAYVRIAYLRKTFEQEPLGKEVSLEQEVLLQCRPPEGIPGAEVEWLKNEDVIDPVEDRNFYITIDHNLIIKQARLSDTANYTCVAKNIVGKRRSTTATVIVYVNGGWSTWTEWSACSNRCGKGYQKRTRTCTNPAPLNGGYICEGQGVQKMACTSLCPEDGEWTAWSKWSTCGTECTHWRRRDCANPP-----PRNGGKDCD-----GPVLQSKNCTDGLCMQVSKSLTKTRHPLIYNVALYVGIVIAVIVCLAISVIV---ALFVYRK--------NHRGFESDIIDTSALNGGFQA-----------VNIKAARQDLLGVPPDL---------TSAAAMYRGPVYALHDV-SDKIPMTNSPLLDPLPNLKIKVYNSSGTVTPQDDLSD--------YTSKLSSQITQSL-LENDTLNMKNQSLARQTDPSCTAFGTFNSLGGHLIIPNSGVSLLIPAGAVPQGRVYEMYVTVHRKENMRPPIEDSQTLLTPVVSCGPPGALMTRPVILTMHHCAETTGEDWKM------------QLKEQSVQGQWEDVVFVGEENFTTPCYIQMESEACHILTETLSTYALVGQSTSKSSA-KRLKLALFG-PTSCTSL--EYNIRVYCLDDTQDALKEVIQQERKVGGQLLDEPKTLHFKGSTHNLRLSIHDVPHSLWKSKLLAKYQEIPFYHIWSGCQ-RNLHCTFTLERFSLSTVELVCKLCVRQVEGEGQ-----IFQLNCTEPSSIIDL----PLMDSASTITTIVGP--SAFSIPLTIRQKLCSSLDAPQTRGHDWRMLAHKLKLDRYLNYFATKPSPTGVILDLWEAQNYPEGNLSTLAAVLEEMGRHE 894
BLAST of Netrin receptor UNC5B vs. Ensembl Xenopus
Match: UNC5D (unc-5 netrin receptor D [Source:NCBI gene;Acc:100490873]) HSP 1 Score: 280.411 bits (716), Expect = 1.347e-79 Identity = 237/919 (25.79%), Postives = 413/919 (44.94%), Query Frame = 2
Query: 347 IPSFIKEPESVYYVYEKKPAKIVCIAEPVSHVNIICNKEVFSYMDLELSESNLRVRKMNKNNEDDLTNGHRWMFSLEITYNQVTEWFNT--FSCVCEAWNQIPSLRLAKKVHSRYGVIKEAYFKSNFKKVPQSKTVVKGQSLILTCVPPESKPKAQVQWMKNKKRL--FENNRIKIVEEHQLLIEDTLLTDSGNYSCIAISLEEKRYSPIAIVKIQESVTENPATQWSAWSACDGNCKKTRTRNCNS----------KGVCKEIDSCTKKECEYNRAVAPFVKNPNKNGVSTSSLQDARDIAMYVGLFVAVTILVMVITIIFCLIRRKALLPLRSTMRYPLNINGNGVAYDVKNSLIKNSNTISTKNPYIMDTSLA-NLTQQRSYLSQSPPNLPPPTCLSEISSTNAYSTGIDFSYNSTGSGKFSQPLIXXXXXXXXXXXXXXXXXXXXDHKPDPLTVSGTPINSRPPSALYHELSLDRESICNSPPFVSENIDIST----LAWGTISTIGGRLCLPQSGITLTIAPGSFINSSSSEMYLAVSRNDPNPPILSDNETLLTPIVLFGPKDVPILKPCVLSVPHSADLRQGNWVIRLLSCVLPDQNDELKEPLCQPIWKNIATIGCETDQTPIYTHLDPYAAFIMLDQPQKICLVGQSYPGGKATKRLRLAAFGRPLSTSSYLPNYNIRIYVFSDTKEAFESVSTIETKLGSTLLDITYQIIFSDSMGNLFFCIEELSTG-WKSQLTTKYQEIPFQDIWSGSQSETLHCAFTFDNIDPSQQSLTCRITAYQSGFYNQKQVITIKQDKLDRSNHKRDLIQHEKVLLYSESNNTYLDPLMT---VFRISNATRKKLCFLLDNVTPRGNDWKQLCRQLSLNGYLNYFMSKVSPTDALVTLWESRNRNENALIDLIISLKAIGRT 3034
+P F+ EP+ Y V + P + C A P + CN E + + +SE ++ D+ T + +T QV ++ + + C C AW+ + + + SR ++ AY + NF++ P+ K V+ ++L C PPE P A+V+W+KN++ + + I H L+I L+DSGNY+C+A ++ KR S A V + + WS WS C C++ R R C + +G+ +E ++CT+ G+ ++A DIA+Y GL A+ I V V+ + L RR S Y +++ + + N T+ N ++++SL +LT R+Y P C + + F+ PL ++ D + ++ S N+R L++ N P++ IS+ A G GGRL +P +G++L I + +S E++L V++ +P+ P L E LL P V GP D+ + P L++PH A++ +W IRL K Q W+ I ++ ET T Y LDP++ I+LD LVG+ A K L++A FG +S +S +YN+R+Y +T AF+ V + E G LL+ + F + ++ + ++ W+ + T QE+PF +W +Q + LHCAF+ + P+ L+C+I Q + ++ ++ L+ + E + ++ ++ + P T F+I ++ R+++C D +G DW+ L ++LS+N L+YF +K SP+ ++ LWE+R + L L +L+ IGRT
Sbjct: 47 LPHFLMEPDDAYIV-KSNPIHLRCRAMPAMQIFFKCNGE-WVHQSEHVSEESV----------DEATGLKIREVYINVTRQQVEDFHGSEDYWCQCIAWSNLGTSK------SRRAFVRIAYLRKNFEQDPKGKEVLIDTMIVLHCRPPEGIPTAEVEWLKNEELIDSLMDENIDTRASHNLIIRQARLSDSGNYTCVASNIVAKRRSASATVIV---FVDGNWDVWSEWSVCSPECEQQRDRKCIAPAPTIGGKPCEGLSQESENCTE-------------------GLCIQGAENASDIALYSGLGAAI-IAVAVLVVGITLYRR-------SQSEYGVDVIDSSALTGGFQTF--NFKTVRQGNSLLLNSSLQPDLTVSRTYSG--------PICFQDPMDKELMTESSIFN-----------PLTDIKVKVQSSFMVSLGVTDRPDFQGKTISGSFPHGNNRCFGTLHNR---------NKLPYIQNLTSISSKPEMRASGHFGHQGGRLVMPNTGVSLLIPHKAIAEDNSWEIFLIVNQGEPSLP-LEGAEVLLGPEVTCGPFDINLSTPVALTIPHCAEVSCEHWNIRL------------KRRSQQGKWEEIMSLDDET--TSFYCLLDPFSCHILLDSFGTYALVGEPLTDC-AVKELKVAVFG-CMSCNSL--DYNLRVYCIDNTPCAFQEVLSNERHQGGQLLEEPKLLHFKGNTFSIQISVLDIPPFLWRIKPFTACQEVPFSRVWCSNQ-QPLHCAFSLERYTPATTQLSCKICVRQ--VKGHELILQVQTSILEN--------ERETIAFFAPEDSNF--PAHTGPKAFKIPHSIRQRICATFDTPNSKGKDWQLLAQKLSINRNLSYFATKNSPSAVILDLWEARYPYDGNLDSLACALEEIGRT 855
BLAST of Netrin receptor UNC5B vs. Ensembl Xenopus
Match: UNC5D (unc-5 netrin receptor D [Source:NCBI gene;Acc:100490873]) HSP 1 Score: 272.707 bits (696), Expect = 1.663e-76 Identity = 247/956 (25.84%), Postives = 419/956 (43.83%), Query Frame = 2
Query: 347 IPSFIKEPESVYYVYEKKPAKIVCIAEPVSHVNIICNKEVFSYMDLELSESNLRVRKMNKNNEDDLTNGHRWMFSLEITYNQVTEWFNT--FSCVCEAWNQIPSLRLAKKVHSRYGVIKEAYFKSNFKKVPQSKTVVKGQSLILTCVPPESKPKAQVQWMKNKKRL--FENNRIKIVEEHQLLIEDTLLTDSGNYSCIAISLEEKRYSPIAIVKIQESVTENPATQWSAWSACDGNCKKT---RTRNC------NSKGVCKE-------------ID---------SCTKKECEYNR-----AVAPFVKNPNKNGVSTSS-----------LQDARDIAMYVGLFVAVTILVMVITIIFCLIRRKALLPLRSTMRYPLNINGNGVAYDVKNSLIKNSNTISTKNPYIMDTSLA-NLTQQRSYLSQSPPNLPPPTCLSEISSTNAYSTGIDFSYNSTGSGKFSQPLIXXXXXXXXXXXXXXXXXXXXDHKPDPLTVSGTPINSRPPSALYHELSLDRESICNSPPFVSENIDIST----LAWGTISTIGGRLCLPQSGITLTIAPGSFINSSSSEMYLAVSRNDPNPPILSDNETLLTPIVLFGPKDVPILKPCVLSVPHSADLRQGNWVIRLLSCVLPDQNDELKEPLCQPIWKNIATIGCETDQTPIYTHLDPYAAFIMLDQPQKICLVGQSYPGGKATKRLRLAAFGRPLSTSSYLPNYNIRIYVFSDTKEAFESVSTIETKLGSTLLDITYQIIFSDSMGNLFFCIEELSTG-WKSQLTTKYQEIPFQDIWSGSQSETLHCAFTFDNIDPSQQSLTCRITAYQSGFYNQKQVITIKQDKLDRSNHKRDLIQHEKVLLYSESNNTYLDPLMT---VFRISNATRKKLCFLLDNVTPRGNDWKQLCRQLSLNGYLNYFMSKVSPTDALVTLWESRNRNENALIDLIISLKAIGRT 3034
+P F+ EP+ Y V + P + C A P + CN E + + +SE ++ D+ T + +T QV ++ + + C C AW+ + + + SR ++ AY + NF++ P+ K V+ ++L C PPE P A+V+W+KN++ + + I H L+I L+DSGNY+C+A ++ KR S A V + + W+ WSAC+ C K R+R C N C +D S ECE R A AP + G+S S ++A DIA+Y GL A+ I V V+ + L RR S Y +++ + + N T+ N ++++SL +LT R+Y P C + + F+ PL ++ D + ++ S N+R L++ N P++ IS+ A G GGRL +P +G++L I + +S E++L V++ +P+ P L E LL P V GP D+ + P L++PH A++ +W IRL K Q W+ I ++ ET T Y LDP++ I+LD LVG+ A K L++A FG +S +S +YN+R+Y +T AF+ V + E G LL+ + F + ++ + ++ W+ + T QE+PF +W +Q + LHCAF+ + P+ L+C+I Q + ++ ++ L+ + E + ++ ++ + P T F+I ++ R+++C D +G DW+ L ++LS+N L+YF +K SP+ ++ LWE+R + L L +L+ IGRT
Sbjct: 50 LPHFLMEPDDAYIV-KSNPIHLRCRAMPAMQIFFKCNGE-WVHQSEHVSEESV----------DEATGLKIREVYINVTRQQVEDFHGSEDYWCQCIAWSNLGTSK------SRRAFVRIAYLRKNFEQDPKGKEVLIDTMIVLHCRPPEGIPTAEVEWLKNEELIDSLMDENIDTRASHNLIIRQARLSDSGNYTCVASNIVAKRRSASATVIV---FVHGGWSSWAEWSACNVRCGKGFQKRSRTCTNPAPLNGGTFCDGPSVQKITCNALCPVDGNWDVWSEWSVCSPECEQQRDRKCIAPAPTIGGKPCEGLSQESENCTEGLCIQGAENASDIALYSGLGAAI-IAVAVLVVGITLYRR-------SQSEYGVDVIDSSALTGGFQTF--NFKTVRQGNSLLLNSSLQPDLTVSRTYSG--------PICFQDPMDKELMTESSIFN-----------PLTDIKVKVQSSFMVSLGVTDRPDFQGKTISGSFPHGNNRCFGTLHNR---------NKLPYIQNLTSISSKPEMRASGHFGHQGGRLVMPNTGVSLLIPHKAIAEDNSWEIFLIVNQGEPSLP-LEGAEVLLGPEVTCGPFDINLSTPVALTIPHCAEVSCEHWNIRL------------KRRSQQGKWEEIMSLDDET--TSFYCLLDPFSCHILLDSFGTYALVGEPLTDC-AVKELKVAVFG-CMSCNSL--DYNLRVYCIDNTPCAFQEVLSNERHQGGQLLEEPKLLHFKGNTFSIQISVLDIPPFLWRIKPFTACQEVPFSRVWCSNQ-QPLHCAFSLERYTPATTQLSCKICVRQ--VKGHELILQVQTSILEN--------ERETIAFFAPEDSNF--PAHTGPKAFKIPHSIRQRICATFDTPNSKGKDWQLLAQKLSINRNLSYFATKNSPSAVILDLWEARYPYDGNLDSLACALEEIGRT 914
BLAST of Netrin receptor UNC5B vs. Ensembl Xenopus
Match: UNC5D (unc-5 netrin receptor D [Source:NCBI gene;Acc:100490873]) HSP 1 Score: 268.47 bits (685), Expect = 6.304e-75 Identity = 247/967 (25.54%), Postives = 419/967 (43.33%), Query Frame = 2
Query: 347 IPSFIKEPESVYYVYEKKPAKIVCIAEPVSHVNIICNKEVFSYMDLELSESNLRVRKMNKNNEDDLTNGHRWMFSLEITYNQVTEWFNT--FSCVCEAWNQIPSLRLAKKVHSRYGVIKEAYFKSNFKKVPQSKTVVKGQSLILTCVPPESKPKAQVQWMKNKKRL--FENNRIKIVEEHQLLIEDTLLTDSGNYSCIAISLEEKRYSPIAIVKIQESVTENPATQWSAWSACDGNCKK---TRTRNC------NSKGVCKE-------------ID---------SCTKKECEYNR-----AVAPFVKNPNKNGVSTSS----------------------LQDARDIAMYVGLFVAVTILVMVITIIFCLIRRKALLPLRSTMRYPLNINGNGVAYDVKNSLIKNSNTISTKNPYIMDTSLA-NLTQQRSYLSQSPPNLPPPTCLSEISSTNAYSTGIDFSYNSTGSGKFSQPLIXXXXXXXXXXXXXXXXXXXXDHKPDPLTVSGTPINSRPPSALYHELSLDRESICNSPPFVSENIDIST----LAWGTISTIGGRLCLPQSGITLTIAPGSFINSSSSEMYLAVSRNDPNPPILSDNETLLTPIVLFGPKDVPILKPCVLSVPHSADLRQGNWVIRLLSCVLPDQNDELKEPLCQPIWKNIATIGCETDQTPIYTHLDPYAAFIMLDQPQKICLVGQSYPGGKATKRLRLAAFGRPLSTSSYLPNYNIRIYVFSDTKEAFESVSTIETKLGSTLLDITYQIIFSDSMGNLFFCIEELSTG-WKSQLTTKYQEIPFQDIWSGSQSETLHCAFTFDNIDPSQQSLTCRITAYQSGFYNQKQVITIKQDKLDRSNHKRDLIQHEKVLLYSESNNTYLDPLMT---VFRISNATRKKLCFLLDNVTPRGNDWKQLCRQLSLNGYLNYFMSKVSPTDALVTLWESRNRNENALIDLIISLKAIGRT 3034
+P F+ EP+ Y V + P + C A P + CN E + + +SE ++ D+ T + +T QV ++ + + C C AW+ + + + SR ++ AY + NF++ P+ K V+ ++L C PPE P A+V+W+KN++ + + I H L+I L+DSGNY+C+A ++ KR S A V + + W+ WSAC+ C K R+R C N C +D S ECE R A AP + G+S S ++A DIA+Y GL A+ I V V+ + L RR S Y +++ + + N T+ N ++++SL +LT R+Y P C + + F+ PL ++ D + ++ S N+R L++ N P++ IS+ A G GGRL +P +G++L I + +S E++L V++ +P+ P L E LL P V GP D+ + P L++PH A++ +W IRL K Q W+ I ++ ET T Y LDP++ I+LD LVG+ A K L++A FG +S +S +YN+R+Y +T AF+ V + E G LL+ + F + ++ + ++ W+ + T QE+PF +W +Q + LHCAF+ + P+ L+C+I Q + ++ ++ L+ + E + ++ ++ + P T F+I ++ R+++C D +G DW+ L ++LS+N L+YF +K SP+ ++ LWE+R + L L +L+ IGRT
Sbjct: 50 LPHFLMEPDDAYIV-KSNPIHLRCRAMPAMQIFFKCNGE-WVHQSEHVSEESV----------DEATGLKIREVYINVTRQQVEDFHGSEDYWCQCIAWSNLGTSK------SRRAFVRIAYLRKNFEQDPKGKEVLIDTMIVLHCRPPEGIPTAEVEWLKNEELIDSLMDENIDTRASHNLIIRQARLSDSGNYTCVASNIVAKRRSASATVIV---FVHGGWSSWAEWSACNVRCGKGFQKRSRTCTNPAPLNGGTFCDGPSVQKITCNALCPVDGNWDVWSEWSVCSPECEQQRDRKCIAPAPTIGGKPCEGLSQESENCTEGLCIQEKKPLHEIRPQSAENASDIALYSGLGAAI-IAVAVLVVGITLYRR-------SQSEYGVDVIDSSALTGGFQTF--NFKTVRQGNSLLLNSSLQPDLTVSRTYSG--------PICFQDPMDKELMTESSIFN-----------PLTDIKVKVQSSFMVSLGVTDRPDFQGKTISGSFPHGNNRCFGTLHNR---------NKLPYIQNLTSISSKPEMRASGHFGHQGGRLVMPNTGVSLLIPHKAIAEDNSWEIFLIVNQGEPSLP-LEGAEVLLGPEVTCGPFDINLSTPVALTIPHCAEVSCEHWNIRL------------KRRSQQGKWEEIMSLDDET--TSFYCLLDPFSCHILLDSFGTYALVGEPLTDC-AVKELKVAVFG-CMSCNSL--DYNLRVYCIDNTPCAFQEVLSNERHQGGQLLEEPKLLHFKGNTFSIQISVLDIPPFLWRIKPFTACQEVPFSRVWCSNQ-QPLHCAFSLERYTPATTQLSCKICVRQ--VKGHELILQVQTSILEN--------ERETIAFFAPEDSNF--PAHTGPKAFKIPHSIRQRICATFDTPNSKGKDWQLLAQKLSINRNLSYFATKNSPSAVILDLWEARYPYDGNLDSLACALEEIGRT 925
BLAST of Netrin receptor UNC5B vs. Ensembl Mouse
Match: Unc5c (unc-5 netrin receptor C [Source:MGI Symbol;Acc:MGI:1095412]) HSP 1 Score: 229.95 bits (585), Expect = 2.686e-62 Identity = 148/433 (34.18%), Postives = 223/433 (51.50%), Query Frame = 2
Query: 1766 VSENIDISTLAWGTISTIGGRLCLPQSGITLTIAPGSFINSSSSEMYLAVSRNDPNPPILSDNETLLTPIVLFGPKDVPILKPCVLSVPHSADLRQGNWVIRLLSCVLPDQNDELKEPLCQPIWKNIATIGCETDQTPIYTHLDPYAAFIMLDQPQKICLVGQSYPGGKATKRLRLAAFGRPLSTSSYLPNYNIRIYVFSDTKEAFESVSTIETKLGSTLLDITYQIIFSDSMGNLFFCIEELSTG-WKSQLTTKYQEIPFQDIWSGSQSETLHCAFTFDNIDPSQQSLTCRITAYQSGFYNQKQVITIKQDKLDRSNHKRDLIQHEKVLLYSESNNTYLDPLMTVFRISNATRKKLCFLLDNVTPRGNDWKQLCRQLSLNGYLNYFMSKVSPTDALVTLWESRNRNENALIDLIISLKAIGRTDCSTLLESD 3061
++ D S A+GT +++GG L +P SG++L I G+ EMY+ V R + P + D++TLLTP+V GP + +P +L++ H AD +W I +LK Q W+++ +G E TP Y LD A I+ + LVGQS A KRL+LA FG PL SS Y+IR+Y DT++A + V +E ++G LL+ + F S+ NL I +++ WKS+L KYQEIPF IWSGSQ LHC FT + + + L C++ Q + Q+ + + DL +L + + T P + F I R+KLC LD RG+DW+ L +L+L+ YLNYF +K SPT ++ LWE++N + L L L+ +GR + L ++
Sbjct: 467 LARQTDPSCTAFGTFNSLGGHLIIPNSGVSLLIPAGAIPQGRVYEMYVTVHRKENMRPPMEDSQTLLTPVVSCGPPGALLTRPVILTLHHCADPSTEDWKI------------QLKNQAVQGQWEDVVVVGEENFTTPCYIQLDAEACHILTENLSTYALVGQSTTKA-AAKRLKLAIFG-PLCCSSL--EYSIRVYCLDDTQDALKEVLQLERQMGGQLLEEPKALHFKGSIHNLRLSIHDIAHSLWKSKLLAKYQEIPFYHIWSGSQ-RNLHCTFTLERLSLNTVELVCKLCVRQ--VEGEGQIFQLNC-TVSEEPTGIDL----PLLDPASTITTVTGP--SAFSIPLPIRQKLCSSLDAPQTRGHDWRMLAHKLNLDRYLNYFATKSSPTGVILDLWEAQNFPDGNLSMLAAVLEEMGRHETVVSLAAE 873 HSP 2 Score: 108.612 bits (270), Expect = 1.511e-23 Identity = 79/307 (25.73%), Postives = 125/307 (40.72%), Query Frame = 2
Query: 569 SLEITYNQVTEWFN--TFSCVCEAWNQIPSLRLAKKVHSRYGVIKEAYFKSNFKKVPQSKTVVKGQSLILTCVPPESKPKAQVQWMKNKKRL--FENNRIKIVEEHQLLIEDTLLTDSGNYSCIAISLEEKRYSPIAIVKI-------------------------QESVTENPA----------------------------TQWSAWSACDGNCKKTRTRNCNS----------KGVCKEIDSCTKKECEYNRAVAPFVKNPNKNGVSTSSLQDARDIAMYVGLFVAVTILVMVITIIFCLIRRK 1288
S+EI+ QV E F + C C AW+ A SR ++ AY + F++ P K V Q ++L C PPE P A+V+W+KN+ + E+ I +H L+I+ L+D+ NY+C+A ++ KR S A V + + NPA T WS WS C C R R C + G+ + +CT C ++ +N SS D+ D+A+YVG+ +AVT+ + + ++ + RK
Sbjct: 49 SIEISRQQVEELFGPEDYWCQCVAWSS------AGTTKSRKAYVRIAYLRKTFEQEPLGKEVSLEQEVLLQCRPPEGIPVAEVEWLKNEDIIDPAEDRNFYITIDHNLIIKQARLSDTANYTCVAKNIVAKRKSTTATVIVYVNGGWSTWTEWSVCNSRCGRGYQKRTRTCTNPAPLNGGAFCEGQSVQKIACTTLCPVDGRWTSWSKWSTCGTECTHWRRRECTAPAPKNGGKDCDGLVLQSKNCTDGLCMQGFIYPISTEHRPQNEYGFSSAPDSDDVALYVGIVIAVTVCLAITVVVALFVYRK 349
BLAST of Netrin receptor UNC5B vs. Ensembl Mouse
Match: Unc5c (unc-5 netrin receptor C [Source:MGI Symbol;Acc:MGI:1095412]) HSP 1 Score: 230.72 bits (587), Expect = 3.345e-62 Identity = 148/433 (34.18%), Postives = 223/433 (51.50%), Query Frame = 2
Query: 1766 VSENIDISTLAWGTISTIGGRLCLPQSGITLTIAPGSFINSSSSEMYLAVSRNDPNPPILSDNETLLTPIVLFGPKDVPILKPCVLSVPHSADLRQGNWVIRLLSCVLPDQNDELKEPLCQPIWKNIATIGCETDQTPIYTHLDPYAAFIMLDQPQKICLVGQSYPGGKATKRLRLAAFGRPLSTSSYLPNYNIRIYVFSDTKEAFESVSTIETKLGSTLLDITYQIIFSDSMGNLFFCIEELSTG-WKSQLTTKYQEIPFQDIWSGSQSETLHCAFTFDNIDPSQQSLTCRITAYQSGFYNQKQVITIKQDKLDRSNHKRDLIQHEKVLLYSESNNTYLDPLMTVFRISNATRKKLCFLLDNVTPRGNDWKQLCRQLSLNGYLNYFMSKVSPTDALVTLWESRNRNENALIDLIISLKAIGRTDCSTLLESD 3061
++ D S A+GT +++GG L +P SG++L I G+ EMY+ V R + P + D++TLLTP+V GP + +P +L++ H AD +W I +LK Q W+++ +G E TP Y LD A I+ + LVGQS A KRL+LA FG PL SS Y+IR+Y DT++A + V +E ++G LL+ + F S+ NL I +++ WKS+L KYQEIPF IWSGSQ LHC FT + + + L C++ Q + Q+ + + DL +L + + T P + F I R+KLC LD RG+DW+ L +L+L+ YLNYF +K SPT ++ LWE++N + L L L+ +GR + L ++
Sbjct: 541 LARQTDPSCTAFGTFNSLGGHLIIPNSGVSLLIPAGAIPQGRVYEMYVTVHRKENMRPPMEDSQTLLTPVVSCGPPGALLTRPVILTLHHCADPSTEDWKI------------QLKNQAVQGQWEDVVVVGEENFTTPCYIQLDAEACHILTENLSTYALVGQSTTKA-AAKRLKLAIFG-PLCCSSL--EYSIRVYCLDDTQDALKEVLQLERQMGGQLLEEPKALHFKGSIHNLRLSIHDIAHSLWKSKLLAKYQEIPFYHIWSGSQ-RNLHCTFTLERLSLNTVELVCKLCVRQ--VEGEGQIFQLNC-TVSEEPTGIDL----PLLDPASTITTVTGP--SAFSIPLPIRQKLCSSLDAPQTRGHDWRMLAHKLNLDRYLNYFATKSSPTGVILDLWEAQNFPDGNLSMLAAVLEEMGRHETVVSLAAE 947 HSP 2 Score: 129.798 bits (325), Expect = 5.511e-30 Identity = 101/388 (26.03%), Postives = 156/388 (40.21%), Query Frame = 2
Query: 341 EGIPSFIKEPESVYYVYEKKPAKIVCIAEPVSHVNIICNKEVFSYMDLELSE-----SNLRVRKMNKNNEDDLTNGHRWMFSLEITYNQVTEWFN--TFSCVCEAWNQIPSLRLAKKVHSRYGVIKEAYFKSNFKKVPQSKTVVKGQSLILTCVPPESKPKAQVQWMKNKKRL--FENNRIKIVEEHQLLIEDTLLTDSGNYSCIAISLEEKRYSPIAIVKI-------------------------QESVTENPA----------------------------TQWSAWSACDGNCKKTRTRNCNS----------KGVCKEIDSCTKKECEYNRAVAPFVKNPNKNGVSTSSLQDARDIAMYVGLFVAVTILVMVITIIFCLIRRK 1288
E +P F+ EPE Y V + KP + C A P + + CN E D + E S L VR++ S+EI+ QV E F + C C AW+ A SR ++ AY + F++ P K V Q ++L C PPE P A+V+W+KN+ + E+ I +H L+I+ L+D+ NY+C+A ++ KR S A V + + NPA T WS WS C C R R C + G+ + +CT C ++ +N SS D+ D+A+YVG+ +AVT+ + + ++ + RK
Sbjct: 59 EPLPHFLIEPEEAYIV-KNKPVNLYCKASPATQIYFKCNSEWVHQKDHVVDERVDETSGLIVREV----------------SIEISRQQVEELFGPEDYWCQCVAWSS------AGTTKSRKAYVRIAYLRKTFEQEPLGKEVSLEQEVLLQCRPPEGIPVAEVEWLKNEDIIDPAEDRNFYITIDHNLIIKQARLSDTANYTCVAKNIVAKRKSTTATVIVYVNGGWSTWTEWSVCNSRCGRGYQKRTRTCTNPAPLNGGAFCEGQSVQKIACTTLCPVDGRWTSWSKWSTCGTECTHWRRRECTAPAPKNGGKDCDGLVLQSKNCTDGLCMQGFIYPISTEHRPQNEYGFSSAPDSDDVALYVGIVIAVTVCLAITVVVALFVYRK 423
BLAST of Netrin receptor UNC5B vs. Ensembl Mouse
Match: Unc5c (unc-5 netrin receptor C [Source:MGI Symbol;Acc:MGI:1095412]) HSP 1 Score: 230.72 bits (587), Expect = 3.345e-62 Identity = 148/433 (34.18%), Postives = 223/433 (51.50%), Query Frame = 2
Query: 1766 VSENIDISTLAWGTISTIGGRLCLPQSGITLTIAPGSFINSSSSEMYLAVSRNDPNPPILSDNETLLTPIVLFGPKDVPILKPCVLSVPHSADLRQGNWVIRLLSCVLPDQNDELKEPLCQPIWKNIATIGCETDQTPIYTHLDPYAAFIMLDQPQKICLVGQSYPGGKATKRLRLAAFGRPLSTSSYLPNYNIRIYVFSDTKEAFESVSTIETKLGSTLLDITYQIIFSDSMGNLFFCIEELSTG-WKSQLTTKYQEIPFQDIWSGSQSETLHCAFTFDNIDPSQQSLTCRITAYQSGFYNQKQVITIKQDKLDRSNHKRDLIQHEKVLLYSESNNTYLDPLMTVFRISNATRKKLCFLLDNVTPRGNDWKQLCRQLSLNGYLNYFMSKVSPTDALVTLWESRNRNENALIDLIISLKAIGRTDCSTLLESD 3061
++ D S A+GT +++GG L +P SG++L I G+ EMY+ V R + P + D++TLLTP+V GP + +P +L++ H AD +W I +LK Q W+++ +G E TP Y LD A I+ + LVGQS A KRL+LA FG PL SS Y+IR+Y DT++A + V +E ++G LL+ + F S+ NL I +++ WKS+L KYQEIPF IWSGSQ LHC FT + + + L C++ Q + Q+ + + DL +L + + T P + F I R+KLC LD RG+DW+ L +L+L+ YLNYF +K SPT ++ LWE++N + L L L+ +GR + L ++
Sbjct: 541 LARQTDPSCTAFGTFNSLGGHLIIPNSGVSLLIPAGAIPQGRVYEMYVTVHRKENMRPPMEDSQTLLTPVVSCGPPGALLTRPVILTLHHCADPSTEDWKI------------QLKNQAVQGQWEDVVVVGEENFTTPCYIQLDAEACHILTENLSTYALVGQSTTKA-AAKRLKLAIFG-PLCCSSL--EYSIRVYCLDDTQDALKEVLQLERQMGGQLLEEPKALHFKGSIHNLRLSIHDIAHSLWKSKLLAKYQEIPFYHIWSGSQ-RNLHCTFTLERLSLNTVELVCKLCVRQ--VEGEGQIFQLNC-TVSEEPTGIDL----PLLDPASTITTVTGP--SAFSIPLPIRQKLCSSLDAPQTRGHDWRMLAHKLNLDRYLNYFATKSSPTGVILDLWEAQNFPDGNLSMLAAVLEEMGRHETVVSLAAE 947 HSP 2 Score: 129.798 bits (325), Expect = 5.511e-30 Identity = 101/388 (26.03%), Postives = 156/388 (40.21%), Query Frame = 2
Query: 341 EGIPSFIKEPESVYYVYEKKPAKIVCIAEPVSHVNIICNKEVFSYMDLELSE-----SNLRVRKMNKNNEDDLTNGHRWMFSLEITYNQVTEWFN--TFSCVCEAWNQIPSLRLAKKVHSRYGVIKEAYFKSNFKKVPQSKTVVKGQSLILTCVPPESKPKAQVQWMKNKKRL--FENNRIKIVEEHQLLIEDTLLTDSGNYSCIAISLEEKRYSPIAIVKI-------------------------QESVTENPA----------------------------TQWSAWSACDGNCKKTRTRNCNS----------KGVCKEIDSCTKKECEYNRAVAPFVKNPNKNGVSTSSLQDARDIAMYVGLFVAVTILVMVITIIFCLIRRK 1288
E +P F+ EPE Y V + KP + C A P + + CN E D + E S L VR++ S+EI+ QV E F + C C AW+ A SR ++ AY + F++ P K V Q ++L C PPE P A+V+W+KN+ + E+ I +H L+I+ L+D+ NY+C+A ++ KR S A V + + NPA T WS WS C C R R C + G+ + +CT C ++ +N SS D+ D+A+YVG+ +AVT+ + + ++ + RK
Sbjct: 59 EPLPHFLIEPEEAYIV-KNKPVNLYCKASPATQIYFKCNSEWVHQKDHVVDERVDETSGLIVREV----------------SIEISRQQVEELFGPEDYWCQCVAWSS------AGTTKSRKAYVRIAYLRKTFEQEPLGKEVSLEQEVLLQCRPPEGIPVAEVEWLKNEDIIDPAEDRNFYITIDHNLIIKQARLSDTANYTCVAKNIVAKRKSTTATVIVYVNGGWSTWTEWSVCNSRCGRGYQKRTRTCTNPAPLNGGAFCEGQSVQKIACTTLCPVDGRWTSWSKWSTCGTECTHWRRRECTAPAPKNGGKDCDGLVLQSKNCTDGLCMQGFIYPISTEHRPQNEYGFSSAPDSDDVALYVGIVIAVTVCLAITVVVALFVYRK 423
BLAST of Netrin receptor UNC5B vs. Ensembl Mouse
Match: Unc5c (unc-5 netrin receptor C [Source:MGI Symbol;Acc:MGI:1095412]) HSP 1 Score: 229.95 bits (585), Expect = 4.341e-62 Identity = 148/433 (34.18%), Postives = 223/433 (51.50%), Query Frame = 2
Query: 1766 VSENIDISTLAWGTISTIGGRLCLPQSGITLTIAPGSFINSSSSEMYLAVSRNDPNPPILSDNETLLTPIVLFGPKDVPILKPCVLSVPHSADLRQGNWVIRLLSCVLPDQNDELKEPLCQPIWKNIATIGCETDQTPIYTHLDPYAAFIMLDQPQKICLVGQSYPGGKATKRLRLAAFGRPLSTSSYLPNYNIRIYVFSDTKEAFESVSTIETKLGSTLLDITYQIIFSDSMGNLFFCIEELSTG-WKSQLTTKYQEIPFQDIWSGSQSETLHCAFTFDNIDPSQQSLTCRITAYQSGFYNQKQVITIKQDKLDRSNHKRDLIQHEKVLLYSESNNTYLDPLMTVFRISNATRKKLCFLLDNVTPRGNDWKQLCRQLSLNGYLNYFMSKVSPTDALVTLWESRNRNENALIDLIISLKAIGRTDCSTLLESD 3061
++ D S A+GT +++GG L +P SG++L I G+ EMY+ V R + P + D++TLLTP+V GP + +P +L++ H AD +W I +LK Q W+++ +G E TP Y LD A I+ + LVGQS A KRL+LA FG PL SS Y+IR+Y DT++A + V +E ++G LL+ + F S+ NL I +++ WKS+L KYQEIPF IWSGSQ LHC FT + + + L C++ Q + Q+ + + DL +L + + T P + F I R+KLC LD RG+DW+ L +L+L+ YLNYF +K SPT ++ LWE++N + L L L+ +GR + L ++
Sbjct: 522 LARQTDPSCTAFGTFNSLGGHLIIPNSGVSLLIPAGAIPQGRVYEMYVTVHRKENMRPPMEDSQTLLTPVVSCGPPGALLTRPVILTLHHCADPSTEDWKI------------QLKNQAVQGQWEDVVVVGEENFTTPCYIQLDAEACHILTENLSTYALVGQSTTKA-AAKRLKLAIFG-PLCCSSL--EYSIRVYCLDDTQDALKEVLQLERQMGGQLLEEPKALHFKGSIHNLRLSIHDIAHSLWKSKLLAKYQEIPFYHIWSGSQ-RNLHCTFTLERLSLNTVELVCKLCVRQ--VEGEGQIFQLNC-TVSEEPTGIDL----PLLDPASTITTVTGP--SAFSIPLPIRQKLCSSLDAPQTRGHDWRMLAHKLNLDRYLNYFATKSSPTGVILDLWEAQNFPDGNLSMLAAVLEEMGRHETVVSLAAE 928 HSP 2 Score: 134.42 bits (337), Expect = 1.686e-31 Identity = 103/372 (27.69%), Postives = 161/372 (43.28%), Query Frame = 2
Query: 341 EGIPSFIKEPESVYYVYEKKPAKIVCIAEPVSHVNIICNKEVFSYMDLELSE-----SNLRVRKMNKNNEDDLTNGHRWMFSLEITYNQVTEWFN--TFSCVCEAWNQIPSLRLAKKVHSRYGVIKEAYFKSNFKKVPQSKTVVKGQSLILTCVPPESKPKAQVQWMKNKKRL--FENNRIKIVEEHQLLIEDTLLTDSGNYSCIAISLEEKRYSPIAIVKIQESVTENPATQWSAWSACDGNCKK---TRTRNC------NSKGVCK----EIDSCT------------------KKECEYNR---AVAPFVKNPNK-------------NGVSTSSLQDARDIAMYVGLFVAVTILVMVITIIFCLIRRK 1288
E +P F+ EPE Y V + KP + C A P + + CN E D + E S L VR++ S+EI+ QV E F + C C AW+ A SR ++ AY + F++ P K V Q ++L C PPE P A+V+W+KN+ + E+ I +H L+I+ L+D+ NY+C+A ++ KR S A V + + W+ WS C+ C + RTR C N C+ + +CT EC + R AP KN K +G+ + D+ D+A+YVG+ +AVT+ + + ++ + RK
Sbjct: 59 EPLPHFLIEPEEAYIV-KNKPVNLYCKASPATQIYFKCNSEWVHQKDHVVDERVDETSGLIVREV----------------SIEISRQQVEELFGPEDYWCQCVAWSS------AGTTKSRKAYVRIAYLRKTFEQEPLGKEVSLEQEVLLQCRPPEGIPVAEVEWLKNEDIIDPAEDRNFYITIDHNLIIKQARLSDTANYTCVAKNIVAKRKSTTATVIV---YVNGGWSTWTEWSVCNSRCGRGYQKRTRTCTNPAPLNGGAFCEGQSVQKIACTTLCPVDGRWTSWSKWSTCGTECTHWRRRECTAPAPKNGGKDCDGLVLQSKNCTDGLCMQAAPDSDDVALYVGIVIAVTVCLAITVVVALFVYRK 404
BLAST of Netrin receptor UNC5B vs. Ensembl Mouse
Match: Unc5b (unc-5 netrin receptor B [Source:MGI Symbol;Acc:MGI:894703]) HSP 1 Score: 227.254 bits (578), Expect = 3.444e-61 Identity = 135/428 (31.54%), Postives = 221/428 (51.64%), Query Frame = 2
Query: 1781 DISTLAWGTISTIGGRLCLPQSGITLTIAPGSFINSSSSEMYLAVSRNDPNPPILSDNETLLTPIVLFGPKDVPILKPCVLSVPHSADLRQGNWVIRLLSCVLPDQNDELKEPLCQPIWKNIATIGCETDQTPIYTHLDPYAAFIMLDQPQKICLVGQSYPGGKATKRLRLAAFGRPLSTSSYLPNYNIRIYVFSDTKEAFESVSTIETKLGSTLLDITYQIIFSDSMGNLFFCIEEL-STGWKSQLTTKYQEIPFQDIWSGSQSETLHCAFTFDNIDPSQQSLTCRITAYQSGFYNQKQVITIKQDKLDRSNHKRDLIQHEKVLLYSESNNTYLDPLMTVFRISNATRKKLCFLLDNVTPRGNDWKQLCRQLSLNGYLNYFMSKVSPTDALVTLWESRNRNENALIDLIISLKAIGRTDCSTLLESD 3061
D S+ GT +GGRL LP +G++L + G+ ++YL +++ + P+ ++T+L+P V GP + + +P VL+VPH A++ G+W+ +LK Q W+ + T+ ET TP Y L+ + I+LDQ +G+SY A KRL+LA F L TS Y++R+Y DT A + V +E LG L++ ++F DS NL + ++ W+S+L KYQEIPF +W+GSQ LHC FT + + TC++ Q + Q+ + + D + + T L P F+I + R+K+C LD RGNDW+ L ++LS++ YLNYF +K SPT ++ LWE+R +++ L L +L+ +G+++ + +D
Sbjct: 529 DPSSSVSGTFGCLGGRLSLPGTGVSLLVPNGAIPQGKFYDLYLHINKAESTLPLSEGSQTVLSPSVTCGPTGLLLCRPVVLTVPHCAEVIAGDWIF------------QLKTQAHQGHWEEVVTLDEETLNTPCYCQLEAKSCHILLDQLGTYVFMGESY-SRSAVKRLQLAIFAPALCTSL---EYSLRVYCLEDTPVALKEVLELERTLGGYLVEEPKPLLFKDSYHNLRLSLHDIPHAHWRSKLLAKYQEIPFYHVWNGSQ-RALHCTFTLERHSLASTEFTCKVCVRQ--VEGEGQIFQLHTTLAETPAGSLDALCSAP----GNAITTQLGPY--AFKIPLSIRQKICSSLDAPNSRGNDWRLLAQKLSMDRYLNYFATKASPTGVILDLWEARQQDDGDLNSLASALEEMGKSEMLVAMATD 931 HSP 2 Score: 115.161 bits (287), Expect = 1.693e-25 Identity = 76/255 (29.80%), Postives = 118/255 (46.27%), Query Frame = 2
Query: 341 EGIPSFIKEPESVYYVYEKKPAKIVCIAEPVSHVNIICNKEVFSYMDLELSES-----NLRVRKMNKNNEDDLTNGHRWMFSLEITYNQVTEWFN--TFSCVCEAWNQIPSLRLAKKVHSRYGVIKEAYFKSNFKKVPQSKTVVKGQSLILTCVPPESKPKAQVQWMKNKKRL--FENNRIKIVEEHQLLIEDTLLTDSGNYSCIAISLEEKRYSPIAIVKIQESVTENPATQWSAWSACDGNCKKT---RTRNC 1069
E +P F+ EP+ Y V + KP ++ C A P + + CN E S D ES LRVR++ +E++ QV E F + C C AW+ + SR I+ AY + NF + P +K V ++L C PPE P A+V+W+KN+ + ++ + +H L+I L+D+ NY+C+A ++ KR S A V + + W+ WS C C + RTR C
Sbjct: 45 EQLPYFLLEPQDAYIV-KNKPVELHCRAFPATQIYFKCNGEWVSQNDHVTQESLDEATGLRVREVQ----------------IEVSRQQVEELFGLEDYWCQCVAWSS------SGTTKSRRAYIRIAYLRKNFDQEPLAKEVPLDHEVLLQCRPPEGVPVAEVEWLKNEDVIDPAQDTNFLLTIDHNLIIRQARLSDTANYTCVAKNIVAKRRSTTATVIV---YVNGGWSSWAEWSPCSNRCGRGWQKRTRTC 273
BLAST of Netrin receptor UNC5B vs. UniProt/SwissProt
Match: sp|C5IAW9|UN5BB_XENLA (Netrin receptor UNC5B-b OS=Xenopus laevis OX=8355 GN=unc5b-b PE=1 SV=1) HSP 1 Score: 338.961 bits (868), Expect = 2.321e-99 Identity = 273/991 (27.55%), Postives = 433/991 (43.69%), Query Frame = 2
Query: 341 EGIPSFIKEPESVYYVYEKKPAKIVCIAEPVSHVNIICNKEVFSYMDLELSESNLRVRKMNKNNEDDLTNGHRWMFSLEITYNQVTEWFN--TFSCVCEAWNQIPSLRLAKKVHSRYGVIKEAYFKSNFKKVPQSKTVVKGQSLILTCVPPESKPKAQVQWMKNKKRL--FENNRIKIVEEHQLLIEDTLLTDSGNYSCIAISLEEKRYSPIAIVKI-----QESVTE--------------------NPA----------------------------TQWSAWSACDGNCKKTRTRNCNS----------KGVCKEIDSCTKKECEYNRAVAPFVKNPNKNGVSTSSLQDARDIAMYVGLFVAVTILVMVITIIFCLIRRKALLPLRSTMR-YPLNINGNGVAYDVKNSLIKNSNTISTKNPYIMDTSLANLTQQRSYL------------SQSPPNLPPPTCLSEI--SSTNAYSTGIDFSYNSTGSGKFSQPLIXXXXXXXXXXXXXXXXXXXXDHKPDPLTVSGTPINSRPPS-ALYHELSLDRESICNSPPFVSENIDISTLAWGTISTIGGRLCLPQSGITLTIAPGSFINSSSSEMYLAVSRNDPNPPILSDNETLLTPIVLFGPKDVPILKPCVLSVPHSADLRQGNWVIRLLSCVLPDQNDELKEPLCQPIWKNIATIGCETDQTPIYTHLDPYAAFIMLDQPQKICLVGQSYPGGKATKRLRLAAFGRPLSTSSYLPNYNIRIYVFSDTKEAFESVSTIETKLGSTLLDITYQIIFSDSMGNLFFCIEEL-STGWKSQLTTKYQEIPFQDIWSGSQSETLHCAFTFDNIDPSQQSLTCRITAYQSGFYNQKQVITIKQDKLDRSNHKRDLIQHEKVLLYSESNNTYLDPLMTVFRISNATRKKLCFLLDNVTPRGNDWKQLCRQLSLNGYLNYFMSKVSPTDALVTLWESRNRNENALIDLIISLKAIGRTDCSTLLESD 3061
E +P F+ EPE Y V + K ++VC A P + + CN E + D + K DD+T +E++ QV E F F C C AW+ A S+ ++ AY + NF + P K V Q +L C PPE P A+V+W+KN++ + ++ I +H L+I+ L+D+ NY+C+A ++ KR S A V + S TE NPA T+WS WSAC C R+R CN+ G+ + +CT C N+ V K + L+ D+A+Y GL VA+ I+++++ + ++ R+ + + + G + K S NS+ I +P + AN R ++ + SP P P ++ SST S GI + G+ KP S +N+R + + H L+L R+S S GT ++GGRL P +G++L I G+ EMYL +++ + +T+L+PI+ GP + + KP +L+VPH AD+ +W++ +LK Q W+ + T+ ET TP Y L+ ++ I+LDQ VG+SY A KRL+LA F L TS YN+++Y DT +A + V +E LG L++ ++F DS NL I ++ + W+S+L KYQEIPF +WSGSQ TLHC FT + + LTC+I Q + Q+ + + H + S T L P F+I R+K+C LD RGNDW+ L ++L ++ YLNYF +K SPT ++ LWE+ ++++ L L +L+ +G+++ ++ +D
Sbjct: 48 ESLPHFLLEPEDAYIV-KNKAVELVCKANPATQIYFKCNGEWVNQND-----------HITKERVDDVTGLVVREVQIEVSRQQVEELFGLEDFWCQCVAWSS------AGTTKSKRSYVRIAYLRKNFDQEPLGKEVALEQEALLQCRPPEGVPPAEVEWLKNEEIIDSTKDTNFLITIDHNLIIKQARLSDTANYTCVAKNIVAKRRSTTATVIVFVNGGWSSWTEWSPCNNRCGHGWQKRTRTCTNPAPLNGGTMCEGQQYQKFACNTMCPVDGGWTEWSKWSACSTECTHWRSRECNAPTPKNGGKDCSGMLLDSKNCTDGLCMQNKRVLGETK--------SHLLESTGDVALYAGLVVAIFIIIILLMAVGIVVYRRNCREFDTDITDSSAALTGGFHPVNFKTSRHDNSHLI---HPAMQPDLTANAGIYRGHMYALQDSADKIPMTNSPLLDPLPNLKIKVYNSSTVGSSPGIHDGNDLLGA------------------------------KPTGTYPSDNIMNARNKNMSTQHLLTLPRDS--------------SNSVTGTFGSLGGRLTFPNTGVSLLIPQGAIPQGKYYEMYLMINKRENTVLPSEGTQTILSPIITCGPTGLLLCKPVILTVPHCADITTSDWIL------------QLKTQSHQGNWEEVVTLNEETLNTPCYCQLESHSCHILLDQLGTYAFVGESY-SRSAIKRLQLAIFAPMLCTSL---EYNLKVYCVEDTPDALKEVLELEKTLGGYLIEEPKPLMFKDSYHNLRLSIHDIPHSLWRSKLLAKYQEIPFYHVWSGSQ-RTLHCTFTLERYSLAATELTCKICVRQ--VEGEGQIFQLHTSLEENVKSFDPFCSHAE-----NSVTTQLGPY--AFKIPFLIRQKICNSLDAPNSRGNDWRLLAQKLCMDRYLNYFATKASPTGVILDLWEALHQDDGDLNTLASALEEMGKSEMMLVMATD 939
BLAST of Netrin receptor UNC5B vs. UniProt/SwissProt
Match: sp|Q7T2Z5|UNC5C_CHICK (Netrin receptor UNC5C OS=Gallus gallus OX=9031 GN=UNC5C PE=2 SV=1) HSP 1 Score: 337.421 bits (864), Expect = 5.534e-99 Identity = 282/997 (28.28%), Postives = 446/997 (44.73%), Query Frame = 2
Query: 248 PKAQIFGVKGNQPTREIEDENDFVKLNES----KLEGIPSFIKEPESVYYVYEKKPAKIVCIAEPVSHVNIICNKEVFSYMDLELSESNLRVRKMNKNNEDDLTNGHRWMFSLEITYNQVTEWFN--TFSCVCEAWNQIPSLRLAKKVHSRYGVIKEAYFKSNFKKVPQSKTVVKGQSLILTCVPPESKPKAQVQWMKNKKRL--FENNRIKIVEEHQLLIEDTLLTDSGNYSCIAISLEEKRYSPIAIVKIQESVTENPATQWSAWSACDGNCKK---TRTRNC------NSKGVCKEID----SCT------------------KKECEYNR---AVAPFVKNPNKN-------------GVSTSSLQDARDIAMYVGLFVAVTILVMVITIIFCLIRRKALLPLRSTMRYPLNINGNGVAYDVKNSLIKNSNTISTKNPYIMDTSLANLTQQRSYLSQSPPNLPPPTCLSEISSTNAYSTGIDFSYNSTGSGKF---SQPLIXXXXXXXXXXXXXXXXXXXXDHKPDPLTVSGTPINSRPPSALYHELSLDRESICNSPPFVSENIDISTLAWGTISTIGGRLCLPQSGITLTIAPGSFINSSSSEMYLAVSRNDPNPPILSDNETLLTPIVLFGPKDVPILKPCVLSVPHSADLRQGNWVIRLLSCVLPDQNDELKEPLCQPIWKNIATIGCETDQTPIYTHLDPYAAFIMLDQPQKICLVGQSYPGGKATKRLRLAAFGRPLSTSSYLPNYNIRIYVFSDTKEAFESVSTIETKLGSTLLDITYQIIFSDSMGNLFFCIEELSTG-WKSQLTTKYQEIPFQDIWSGSQSETLHCAFTFDNIDPSQQSLTCRITAYQSGFYNQKQVITIKQDKLDRSNHKRDLIQHEKVLLYSESNNTYLDPLMTVFRISNATRKKLCFLLDNVTPRGNDWKQLCRQLSLNGYLNYFMSKVSPTDALVTLWESRNRNENALIDLIISLKAIGRTDCSTLLESD 3061
P + G ++P +D++ F +L E+ E +P F+ EPE Y V + KP + C A P + + CN E D + E RV D+ + S+EI+ QV E F + C C AW+ A SR ++ AY + F++ P K V Q ++L C PPE P A+V+W+KN++ + E+ I +H L+I+ L+D+ NY+C+A ++ KR S A V + + W+ WSAC+ C + RTR C N C+ + +CT EC + R AP KN K+ G+ + D+ D+A+YVG+ +AV + + + ++ AL R R D ++ +I +S P N+ R L PP+L +S A G ++ + S K + P++ + + + +++ D D +S+ + L L+ E++ ++ D S A+GT +++GG L +P SG++L I G+ EMY+ V R + P + D++TLLTP+V GP + +P VL++ H A+ +W I +LK Q W+++ +G E TP Y LDP A I+ + LVGQS A KRL+LA FG PLS SS Y+IR+Y DT++A + V +E ++G LL+ + F S NL I +++ WKS+L KYQEIPF IWSG Q LHC FT + + L C++ Q + Q+ +L+ S + ++ + S T + P F I R+KLC LD RG+DW+ L +L L+ YLNYF +K SPT ++ LWE++N + L L L+ +GR + L ++
Sbjct: 26 PALAVLG--ASRPGSAAQDDDFFHELPETFPSDPPEPLPHFLIEPEEAYIV-KNKPVNLYCKASPATQIYFKCNSEWVHQKDHVVDE---RV--------DETSGLIVCEVSIEISRQQVEELFGPEDYWCQCVAWSS------AGTTKSRKAYVRIAYLRKTFEQEPLGKEVSLEQEVLLQCRPPEGIPVAEVEWLKNEEVIDPVEDRNFYITIDHNLIIKQARLSDTANYTCVAKNIVAKRKSTTATVIV---YVNGGWSTWTEWSACNSRCGRGFQKRTRTCTNPAPLNGGAFCEGQNVQKIACTTLCPVDGKWTSWSKWSTCGTECTHWRRRECTAPAPKNGGKDCEGLVLQSKNCTDGLCMQAAPDSDDVALYVGIVIAVIVCLAISVVV-------ALFVYRKNHR------------DFESDIIDSSALNGGFQP-------VNIKAARQDLLAVPPDL---------TSAAAMYRGPVYALHDV-SDKIPMTNSPILDPLPNLKIKVYNTSGAVTPQDELSD--------FSSKLSPQITQSL-LENETLNVKNQSLARQTDPSCTAFGTFNSLGGHLVIPNSGVSLLIPAGAVPQGRVYEMYVTVHRKEGMRPPVEDSQTLLTPVVSCGPPGALLTRPVVLTMHHCAEPNMDDWQI------------QLKHQAGQGPWEDVVVVGEENFTTPCYIQLDPEACHILTETLSTYALVGQSITKA-AAKRLKLAIFG-PLSCSSL--EYSIRVYCLDDTQDALKEVLQLERQMGGQLLEEPKTLHFKGSTHNLRLSIHDIAHSLWKSKLPAKYQEIPFYHIWSGCQ-RNLHCTFTLERFSLNTLELVCKLCVRQ--VEGEGQIF-----QLNCSVSEEPTGIDYPIMDSAGSITTIVGP--NAFSIPLPIRQKLCSSLDAPQTRGHDWRMLAHKLKLDRYLNYFATKSSPTGVILDLWEAQNFPDGNLSMLAAVLEEMGRHETVVSLAAE 928
BLAST of Netrin receptor UNC5B vs. UniProt/SwissProt
Match: sp|Q8JGT4|UN5BA_XENLA (Netrin receptor UNC5B-a OS=Xenopus laevis OX=8355 GN=unc5b-a PE=2 SV=1) HSP 1 Score: 335.495 bits (859), Expect = 4.458e-98 Identity = 277/995 (27.84%), Postives = 440/995 (44.22%), Query Frame = 2
Query: 341 EGIPSFIKEPESVYYVYEKKPAKIVCIAEPVSHVNIICNKEVFSYMDLELSESNLRVRKMNKNNEDDLTNGHRWMFSLEITYNQVTEWFN--TFSCVCEAWNQIPSLRLAKKVHSRYGVIKEAYFKSNFKKVPQSKTVVKGQSLILTCVPPESKPKAQVQWMKNKKRL--FENNRIKIVEEHQLLIEDTLLTDSGNYSCIAISLEEKRYSPIAIVKI-----QESVTE--------------------NPA----------------------------TQWSAWSACDGNCKKTRTRNCNS----------KGVCKEIDSCTKKECEYNRAVAPFVKNPNKNGVSTSSLQDARDIAMYVGLFVAVTILVMVITIIFCLIRRKALLPLRSTMRYPLNINGNGVAY-------DVKNSLIKNSNTIS-------TKNPYIMDTSLANL--TQQRSYLSQSPPNLPPPTCLSEI--SSTNAYSTGIDFSYNSTGSGKFSQPLIXXXXXXXXXXXXXXXXXXXXDHKPDPLTVSGTPI-NSRPPS-ALYHELSLDRESICNSPPFVSENIDISTLAWGTISTIGGRLCLPQSGITLTIAPGSFINSSSSEMYLAVSRNDPNPPILSDNETLLTPIVLFGPKDVPILKPCVLSVPHSADLRQGNWVIRLLSCVLPDQNDELKEPLCQPIWKNIATIGCETDQTPIYTHLDPYAAFIMLDQPQKICLVGQSYPGGKATKRLRLAAFGRPLSTSSYLPNYNIRIYVFSDTKEAFESVSTIETKLGSTLLDITYQIIFSDSMGNLFFCIEEL-STGWKSQLTTKYQEIPFQDIWSGSQSETLHCAFTFDNIDPSQQSLTCRITAYQSGFYNQKQVITIKQDKLDRSNHKRDLIQHEKVLLYSESNNTYLDPLMTVFRISNATRKKLCFLLDNVTPRGNDWKQLCRQLSLNGYLNYFMSKVSPTDALVTLWESRNRNENALIDLIISLKAIGRTDCSTLLESD 3061
E +P F+ EPE Y V + KP ++VC A P + + CN E + D + K DD+T +E++ QV E F + C C AW+ A S+ ++ AY + NF + P K V Q +L C PPE P A+V+W+KN++ + ++ I +H L+I+ L+D+ NY+C++ ++ KR S A V + S TE NPA T+WS WSAC C R+R CN+ G+ + +CT C N+ V K + L+ D+A+Y GL VA+ I+++++ + ++ R R+ + +I + A + K S NS I T N I ++ L + + ++ SP P P ++ SST S GI N G+ KP S I N+R + ++ H L+L R+S S GT ++GGRL P +G++L I G+ EMYL +++ + +T+L+PI+ GP + + KP +L+VPH AD+ +W++ +LK Q W+ + T+ ET TP Y L+ ++ +LDQ VG+SY A KRL+LA F L TS YN+++Y DT +A + V +E LG L++ ++F DS NL I ++ + W+S+L KYQEIPF IWSGSQ TLHC FT + + LTC+I Q + Q+ + L+ + D + S T+L P F+I + R+K+C LD RGNDW+ L ++L ++ YLNYF +K SPT ++ LWE+ ++++ L L +L+ +G+++ ++ +D
Sbjct: 48 ESLPHFLLEPEDAYIV-KNKPVELVCKANPATQIYFKCNGEWVNQND-----------HITKERVDDVTGLVVREVQIEVSRQQVEELFGLEDYWCQCVAWSS------AGTTKSKRSYVRIAYLRKNFDQEPLGKEVALEQEALLQCRPPEGVPPAEVEWLKNEEIIDPTKDTNFLITIDHNLIIKQARLSDTANYTCVSKNIVAKRRSTTATVIVFVNGGWSSWTEWSPCNNRCGHGWQKRTRTCTNPAPLNGGTMCEGQQYQKFACNTMCPVDGGWTEWSKWSACSTECTHWRSRECNAPTPKNGGKDCSGMLLDSKNCTDGLCMQNKRVLGETK--------SRLLESTGDVALYAGLVVAIFIVIILLMAVGIVVYR------RNCREFDTDITDSSAALTGGFHPVNFKTSRHDNSQLIHPAMQPDLTANAGIYRGNMYALQDSADKIPMTNSPLLDPLPNLKIKVYNSSTVGSSPGIHDGNNLLGT------------------------------KPTGTYPSDNNIMNARNKNMSMQHLLTLPRDS--------------SNSVTGTFGSLGGRLTFPNTGVSLLIPQGAIPQGKYYEMYLMINKRENTVLPSEGTQTILSPIITCGPTGLLLCKPVILTVPHCADINTSDWIL------------QLKTQSHQGNWEEVVTLNEETLNTPCYCQLESHSCHTLLDQLGTYAFVGESY-SRSAIKRLQLAIFAPMLCTSL---EYNLKVYCVEDTPDALKEVLELEKTLGGYLVEEPKLLMFKDSYHNLRLSIHDIPHSLWRSKLMAKYQEIPFYHIWSGSQ-RTLHCTFTLERYSLAATELTCKICVRQ--VEGEGQIFQL-HTLLEENVKSFDPFCSQA----ENSVTTHLGPY--AFKIPFSIRQKICNSLDAPNSRGNDWRLLAQKLCMDRYLNYFATKASPTGVILDLWEALHQDDGDLNTLASALEEMGKSEMMLVMATD 940
BLAST of Netrin receptor UNC5B vs. UniProt/SwissProt
Match: sp|O95185|UNC5C_HUMAN (Netrin receptor UNC5C OS=Homo sapiens OX=9606 GN=UNC5C PE=1 SV=2) HSP 1 Score: 317.005 bits (811), Expect = 1.540e-91 Identity = 281/986 (28.50%), Postives = 439/986 (44.52%), Query Frame = 2
Query: 299 EDENDFVKLNES----KLEGIPSFIKEPESVYYVYEKKPAKIVCIAEPVSHVNIICNKEVFSYMDLELSE-----SNLRVRKMNKNNEDDLTNGHRWMFSLEITYNQVTEWFN--TFSCVCEAWNQIPSLRLAKKVHSRYGVIKEAYFKSNFKKVPQSKTVVKGQSLILTCVPPESKPKAQVQWMKNKKRL--FENNRIKIVEEHQLLIEDTLLTDSGNYSCIAISLEEKRYSPIAIVKIQESVTENPATQWSAWSACDGNCKK---TRTRNC------NSKGVCK----EIDSCT------------------KKECEYNR---AVAPFVKNPNKN-------------GVSTSSLQDARDIAMYVGLFVAVTILVMVITIIFCLIRRKALLPLRSTMRYPLNINGNGVAYDVKNSLIKNSNTISTKNPYIMDTSLANLTQQRSYLSQSPPNLPPPTCLSEISSTNAYSTGIDFSYNSTGSGKF---SQPLIXXXXXXXXXXXXXXXXXXXXDHKPDPLTVSGTPINSRPPSALYHE-LSLDRESICNSPPFVSENIDISTLAWGTISTIGGRLCLPQSGITLTIAPGSFINSSSSEMYLAVSRNDPNPPILSDNETLLTPIVLFGPKDVPILKPCVLSVPHSADLRQGNWVIRLLSCVLPDQNDELKEPLCQPIWKNIATIGCETDQTPIYTHLDPYAAFIMLDQPQKICLVGQSYPGGKATKRLRLAAFGRPLSTSSYLPNYNIRIYVFSDTKEAFESVSTIETKLGSTLLDITYQIIFSDSMGNLFFCIEELSTG-WKSQLTTKYQEIPFQDIWSGSQSETLHCAFTFDNIDPSQQSLTCRITAYQSGFYNQKQVITIKQDKLDRSNHKRDLIQHEKVLLYSESNNTYLDPLMTVFRISNATRKKLCFLLDNVTPRGNDWKQLCRQLSLNGYLNYFMSKVSPTDALVTLWESRNRNENALIDLIISLKAIGRTDCSTLLESD 3061
+D++ F +L E+ E +P F+ EPE Y V + KP + C A P + + CN E D + E S L VR++ S+EI+ QV E F + C C AW+ A SR ++ AY + F++ P K V Q ++L C PPE P A+V+W+KN+ + E+ I +H L+I+ L+D+ NY+C+A ++ KR S A V + + W+ WS C+ C + RTR C N C+ + +CT EC + R AP KN K+ G+ + D+ D+A+YVG + I V+V I ++ AL R R D ++ +I +S P N+ R L PP+L +S A G ++ + S K + P++ + + + +++ D + T +P ++ S L +E LSL +S+ + D S A+G+ +++GG L +P SG++L I G+ EMY+ V R + P + D++TLLTP+V GP + +P VL++ H AD +W I LK Q W+++ +G E TP Y LD A I+ + LVG S A KRL+LA FG PL SS Y+IR+Y DT++A + + +E ++G LL+ + F S NL I +++ WKS+L KYQEIPF +WSGSQ LHC FT + + L C++ Q + Q+ + + DL +L + + T P + F I R+KLC LD RG+DW+ L +L+L+ YLNYF +K SPT ++ LWE++N + L L L+ +GR + L ++
Sbjct: 41 QDDDFFHELPETFPSDPPEPLPHFLIEPEEAYIV-KNKPVNLYCKASPATQIYFKCNSEWVHQKDHIVDERVDETSGLIVREV----------------SIEISRQQVEELFGPEDYWCQCVAWSS------AGTTKSRKAYVRIAYLRKTFEQEPLGKEVSLEQEVLLQCRPPEGIPVAEVEWLKNEDIIDPVEDRNFYITIDHNLIIKQARLSDTANYTCVAKNIVAKRKSTTATVIV---YVNGGWSTWTEWSVCNSRCGRGYQKRTRTCTNPAPLNGGAFCEGQSVQKIACTTLCPVDGRWTPWSKWSTCGTECTHWRRRECTAPAPKNGGKDCDGLVLQSKNCTDGLCMQTAPDSDDVALYVG----IVIAVIVCLAISVVV---ALFVYRKNHR------------DFESDIIDSSALNGGFQP-------VNIKAARQDLLAVPPDL---------TSAAAMYRGPVYALHDV-SDKIPMTNSPILDPLPNLKIKVYNTSGAVTPQDDLSE-FTSKLSPQMTQ--SLLENEALSLKNQSL-------ARQTDPSCTAFGSFNSLGGHLIVPNSGVSLLIPAGAIPQGRVYEMYVTVHRKETMRPPMDDSQTLLTPVVSCGPPGALLTRPVVLTMHHCADPNTEDWKIL------------LKNQAAQGQWEDVVVVGEENFTTPCYIQLDAEACHILTENLSTYALVGHSTTKA-AAKRLKLAIFG-PLCCSSL--EYSIRVYCLDDTQDALKEILHLERQMGGQLLEEPKALHFKGSTHNLRLSIHDIAHSLWKSKLLAKYQEIPFYHVWSGSQ-RNLHCTFTLERFSLNTVELVCKLCVRQ--VEGEGQIFQLNC-TVSEEPTGIDL----PLLDPANTITTVTGP--SAFSIPLPIRQKLCSSLDAPQTRGHDWRMLAHKLNLDRYLNYFATKSSPTGVILDLWEAQNFPDGNLSMLAAVLEEMGRHETVVSLAAE 928
BLAST of Netrin receptor UNC5B vs. UniProt/SwissProt
Match: sp|Q8IZJ1|UNC5B_HUMAN (Netrin receptor UNC5B OS=Homo sapiens OX=9606 GN=UNC5B PE=1 SV=2) HSP 1 Score: 230.335 bits (586), Expect = 2.819e-61 Identity = 137/421 (32.54%), Postives = 217/421 (51.54%), Query Frame = 2
Query: 1802 GTISTIGGRLCLPQSGITLTIAPGSFINSSSSEMYLAVSRNDPNPPILSDNETLLTPIVLFGPKDVPILKPCVLSVPHSADLRQGNWVIRLLSCVLPDQNDELKEPLCQPIWKNIATIGCETDQTPIYTHLDPYAAFIMLDQPQKICLVGQSYPGGKATKRLRLAAFGRPLSTSSYLPNYNIRIYVFSDTKEAFESVSTIETKLGSTLLDITYQIIFSDSMGNLFFCIEEL-STGWKSQLTTKYQEIPFQDIWSGSQSETLHCAFTFDNIDPSQQSLTCRITAYQSGFYNQKQVITIKQDKLDRSNHKRDLIQHEKVLLYSESNNTYLDPLMTVFRISNATRKKLCFLLDNVTPRGNDWKQLCRQLSLNGYLNYFMSKVSPTDALVTLWESRNRNENALIDLIISLKAIGRTDCSTLLESD 3061
GT +GGRL +P +G++L + G+ EMYL +++ + P+ +T+L+P V GP + + +P +L++PH A++ +W+ +LK Q W+ + T+ ET TP Y L+P A I+LDQ G+SY A KRL+LA F L TS Y++R+Y DT A + V +E LG L++ ++F DS NL + +L W+S+L KYQEIPF IWSGSQ + LHC FT + + LTC+I Q + Q+ + + D + + T L P F+I + R+K+C LD RGNDW+ L ++LS++ YLNYF +K SPT ++ LWE+ +++ L L +L+ +G+++ + +D
Sbjct: 547 GTFGCLGGRLSIPGTGVSLLVPNGAIPQGKFYEMYLLINKAESTLPLSEGTQTVLSPSVTCGPTGLLLCRPVILTMPHCAEVSARDWIF------------QLKTQAHQGHWEEVVTLDEETLNTPCYCQLEPRACHILLDQLGTYVFTGESY-SRSAVKRLQLAVFAPALCTSL---EYSLRVYCLEDTPVALKEVLELERTLGGYLVEEPKPLMFKDSYHNLRLSLHDLPHAHWRSKLLAKYQEIPFYHIWSGSQ-KALHCTFTLERHSLASTELTCKICVRQ--VEGEGQIFQLHTTLAETPAGSLDTLCSAP----GSTVTTQLGPY--AFKIPLSIRQKICNSLDAPNSRGNDWRMLAQKLSMDRYLNYFATKASPTGVILDLWEALQQDDGDLNSLASALEEMGKSEMLVAVATD 942 HSP 2 Score: 115.931 bits (289), Expect = 7.049e-25 Identity = 97/388 (25.00%), Postives = 159/388 (40.98%), Query Frame = 2
Query: 341 EGIPSFIKEPESVYYVYEKKPAKIVCIAEPVSHVNIICNKEVFSYMDLELSE-----SNLRVRKMNKNNEDDLTNGHRWMFSLEITYNQVTEWFN--TFSCVCEAWNQIPSLRLAKKVHSRYGVIKEAYFKSNFKKVPQSKTVVKGQSLILTCVPPESKPKAQVQWMKNKKRL--FENNRIKIVEEHQLLIEDTLLTDSGNYSCIAISLEEKRYSPIAIVKI-------------------------QESVTENPA----------------------------TQWSAWSACDGNCKKTRTRNC----------NSKGVCKEIDSCTKKECEYNRAVAPFVKNPNKNGVSTSSLQDARDIAMYVGLFVAVTILVMVITIIFCLIRRK 1288
E +P F++EP+ Y V + KP ++ C A P + + CN E S D E + LRVR++ +E++ QV E F + C C AW+ A SR ++ AY + NF + P K V ++L C PPE P A+V+W+KN+ + ++ + +H L+I L+D+ NY+C+A ++ KR S A V + + NPA T+WS WSAC C R+R C + G + +CT C N+ + +PN + L+ + D A+Y GL VA+ ++V ++ + ++ R+
Sbjct: 45 EPLPYFLQEPQDAYIV-KNKPVELRCRAFPATQIYFKCNGEWVSQNDHVTQEGLDEATGLRVREVQ----------------IEVSRQQVEELFGLEDYWCQCVAWSS------AGTTKSRRAYVRIAYLRKNFDQEPLGKEVPLDHEVLLQCRPPEGVPVAEVEWLKNEDVIDPTQDTNFLLTIDHNLIIRQARLSDTANYTCVAKNIVAKRRSTTATVIVYVNGGWSSWAEWSPCSNRCGRGWQKRTRTCTNPAPLNGGAFCEGQAFQKTACTTICPVDGAWTEWSKWSACSTECAHWRSRECMAPPPQNGGRDCSGTLLDSKNCTDGLCMQNKKT---LSDPNSH-----LLEASGDAALYAGLVVAIFVVVAILMAVGVVVYRR 401
BLAST of Netrin receptor UNC5B vs. TrEMBL
Match: E1CHK7 (Uncoordinated 5 OS=Dugesia japonica OX=6161 GN=Djunc5A PE=2 SV=1) HSP 1 Score: 518.079 bits (1333), Expect = 2.063e-163 Identity = 352/1002 (35.13%), Postives = 527/1002 (52.59%), Query Frame = 2
Query: 293 EIEDENDFVKLNESKLEGIPSFIKEPESVYYVYEKKPAKIVCIAEPVSHVNIICNKEVFSYMDLELSESNLRVRKMNKNNEDDLTNGHRWMFSLEITYNQVTEWFNTFSCVCEAWNQIPSLRLAKKVHSRYGVIKEAYFKSNFKKVPQSKTVVKGQSLILTCVPPESKPKAQVQWMKNKKRLFENN--RIKIVEEHQLLIEDTLLTDSGNYSCIAISLEEKRYSPIAIVKIQESVTENPATQWSAWSACDGNCK--------------KTRTRNC----------NSKGVCKEIDSCTK----------------------------KECEYNRAVAPFVKNPNKNGV-----STSSLQDARDIAMYVGLFVAVTILVMVITIIFCLIRRKALLPL--RSTMRYPLNINGNGVAYDVKNS------LIKN---SNTISTKNPYIMDTSLANLTQQRSYLSQSPPNLPPPTCLSEISSTNAYSTGIDFSYNSTGSGKFSQPLIXXXXXXXXXXXXXXXXXXXXDHKPDPLTVSGTPINSRPPSALYHELSLDRESICNSPPFVSENIDISTLAWGTISTIGGRLCLPQSGITLTIAPGSFINSSSSEMYLAVSRNDPNPPILSDNETLLTPIVLFGPKDVPILKPCVLSVPHSADLRQGNWVIRLLSCVLPDQNDELKEPLCQPIWKNIATIG-CETDQTPIYTHLDPYAAFIMLDQPQKICLVGQSYP--GGKATKRLRLAAFGRPLSTSSYLPNYNIRIYVFSDTKEAFESVSTIETKLGSTLLDITYQIIFSDSMGNLFFCIEELSTGWKSQLTTKYQEIPFQDIWSGSQSETLHCAFTFDNIDPSQQSLTCRITAYQSGF-YNQKQVITIKQDKLDRSNHKRDLIQHEKVLLYSESNN-----TYLDPLMTVFRISNATRKKLCFLLDNVTPRGNDWKQLCRQLSLNGYLNYFMSKVSPTDALVTLWESRNRNENALIDLIISLKAIGRTDCSTLLESD 3061
E++ + D V+ NE +GIP F+ EP YYV + PA I+C+AEPVSHVNI C + FSYM+ E SES L V KMN N+ D + G+RW FSLE+ Y V EWF+ + C CEAWNQI + KKVHS +I+E+YF+++FK P+S+ + +G L L C PPESKP ++V W+KN + + ++N I I E +L+IE L +DSGNY+C+A S + S A++ I +P W+ W+ C CK + R R C + KG E +SC K + CE+ P ++ N + + S + +++ MY+GLF+ ++IL ++I II CLI +K + L R M + + NG Y K+S L+ N S ++ KN D +L LS+ P N P + ++ + I Y +++ P + ++ + + S D K + S LY ELS+ R S ++ ++++ T+AWGTI+T GGRLCLPQSGI+LTI G+ + +S EM+LAV R+ N P++ E LL+P++L GP + +LK +L++PH A+++ +W IR+LS QN ++ P+WK ++TI + IY LD +A +++DQ Q IC+ G P + RLR+ AF PLS+ ++ IR+++ DTKEA E+V E KL LLD + + FS S G++ C+++LS GW+ + K Q + IW + S+ F +++DP++ +C IT Q NQ V IK+ RS + R +I + L S SNN YLDPL TVFR+S TR++L LLD W+ L + LNG LNYF K+SP+DAL+ LWE+R R+E A+ DLI L+ IGR DC+ ++E D
Sbjct: 41 EVDGKKDLVQPNEKHYDGIPKFLVEPHPFYYVNKTHPALIICVAEPVSHVNIFCADKQFSYMNTERSESGLIVIKMNHLNQPD-SKGNRWKFSLEVKYKDVLEWFSEYKCYCEAWNQITMINKDKKVHSSAALIQESYFQNDFKTTPKSQELREGNKLELQCTPPESKPNSKVTWLKNDELITQSNFPLIIIDESKRLIIEQVLKSDSGNYTCVAQSQGVVKKSKPAVIIITMKYNWSP---WAKWNTCPEICKMETKCQNEICSSSHRQRIRYCLNEEIKVEDKHCKGESNEKESCDKACEKEESKWNSWSFWTTICFPNCSQTRVRRCEFGNCFGPKQQSRNCSQIICQRADPSLILESQSTTMYLGLFITISILFIIILIILCLITQKGYISLLPRRGMVFSNHNNGMTKIYTNKSSKNSEKFLLNNDQKSTIVTIKNHNAQDLVATSL------LSEIPNNYSPVYEMHSNNNRDQVLPAIYSDYPMISKSQYTYPSTAPLLNSILSPERSYNETSEEDQK------------ANLSSPLYQELSIGRGSCGLLSNYLPPDMELDTIAWGTITTAGGRLCLPQSGISLTIPRGAIHHGNSEEMFLAVCRDHTNIPVIDMMEMLLSPVILCGPPQIQLLKSVILTIPHCANIQCSDWNIRVLSARF--QNSQIP-----PLWKELSTIRPVNRSDSNIYAQLDSTSAHLIIDQLQMICITGCLSPLSDSSVSIRLRILAFSLPLSSEL---DHIIRVHLIPDTKEAIENVIASELKLNGQLLDNSKKFTFSSSGGDIALCLDDLSLGWRCHSSNKMQTFSYSFIWRLNHSQNQEIHFLLEHVDPTRTGFSCNITIQQIDLPQNQVIVRVIKE----RSPNNRSII---PISLDSRSNNREFSQAYLDPLQTVFRLSFTTRQQLWPLLD------PSWQTLANHMLLNGNLNYFSEKMSPSDALLDLWEARCRDEGAIADLINILRVIGRNDCAMIVEQD 997
BLAST of Netrin receptor UNC5B vs. TrEMBL
Match: A0A1S3JPD5 (netrin receptor UNC5C-like isoform X4 OS=Lingula unguis OX=7574 GN=LOC106174972 PE=4 SV=1) HSP 1 Score: 421.394 bits (1082), Expect = 1.195e-127 Identity = 291/938 (31.02%), Postives = 466/938 (49.68%), Query Frame = 2
Query: 350 PSFIKEPESVYYVYEKKPAKIVCIAEPVSHVNIICNKEVFSYMDLELSESNLRVRKMNKNNEDDLTNGHRWMFSLEITYNQVTEWF--NTFSCVCEAWNQIPSLRLA--------KKVHSRYGVIKEAYFKSNFKKVPQSKTVVKGQSLILTCVPPESKPKAQVQWMKNKKRL--FENNRIKIVEEHQLLIEDTLLTDSGNYSCIAISLEEKRYSPIAIVKIQESVTENPATQWSAWSACDGNCKK---TRTRNCNSKGVCKEIDSCTKKECEYNRAVAPFVKNPNKNGVSTSSLQDARDIAMYVGLFVAVTILVMVITIIFCLIRRKALLPLRSTMRYPLNINGNGV-AYDVKNSLIKNSNTISTKNPYIMDTSLANL---TQQRSYLSQSPPNLPPPTCLSEISSTNAYSTGIDFSYNSTGSGKFSQPLIXXXXXXXXXXXXXXXXXXXXDH---KPDPLTVSGTPINSRPPSALYHELSLDRESICNSPPFVSENIDISTLAWGTISTIGGRLCLPQSGITLTIAPGSFINSSSSEMYLAVSRNDPNPPILSDNETLLTPIVLFGPKDVPILKPCVLSVPHSADLRQGNWVIRLLSCVLPDQNDELKEPLCQPIWKNIATIGCETDQTPIYTHLDPYAAFIMLDQPQKICLVGQSYPGGKATKRLRLAAFGRPLSTSSYLPNYNIRIYVFSDTKEAFESVSTIETKLGSTLLDITYQIIFSDSMGNLFFCIEELSTGWKSQLTTKYQEIPFQDIWSGSQSETLHCAFTFDNIDPSQQSLTCRITAYQSGFYNQKQVITIKQDKLDRSNHKRDLIQHEKVLLYSESNNTY----------LDPLMTVFRISNATRKKLCFLLDNVTPRGNDWKQLCRQLSLNGYLNYFMSKVSPTDALVTLWESRNRNENALIDLIISLKAIGRTDCSTLLESDCG 3067
P F++EPE Y+ + KP I C A + C +E ++ L+ R + + T S+E+T V E+F + + C C AW +IPS V SR G+++ A+ + F++ P S +V + + L C+PP P +V W+K+ + + E I E L+I L+D GN++C AI++ R S A + + + + WS WS CD C K +R+R C++ C ++ + V P K G QD +DIA+YVG+ +AV +L +I II +IRRK ++ +++ + YD + + KN ++ L + S Q PPN + +I N ++ ++ S P+I S +T+ + ++ + SRP S Y + +R+S+ ++ + NID+ LAWG I+ GG L +P++G++++I G+ ++ E+++AV R+D + P LSD +T+L+PI+L GP+ + + KP ++S H A + G WV+R+ EP P WK++ T G ET TPIY +D +M DQ + L+G+S G A KRLRLAAF +++S +Y+IR+YV DT++A E V +E KLG+ LLD QI+F D NL IEEL+ GW+S+LT YQEIPF+ IWSG+Q+ LHC+F+ ++ D QQ+++C+I YQ + V+ I SN +I V ++ T LD FR+ + + KLC LD RGNDW+ L + L ++ Y+N+F SK SPT+ ++ LWE+R+R E AL DL+ +L+ + R D + +LE + G
Sbjct: 50 PIFLQEPEPHNYIVKSKPVTITCQAINAVDITFRCAEE---WVPLK--------RHVRADFTHPETGEAVLQASVEVTRQAVEEYFGIDGYWCECNAWTEIPSPDRPWTGDNPPPAHVSSRRGLVQVAFIRKRFEREPISTSVELEKPVQLHCLPPTGVPPPEVFWLKDGQVINDKEETNFIISNEGNLIISQARLSDQGNFTCGAINVAATRKSESAELIV---YVKGAWSTWSQWSDCDSKCGKGFQSRSRTCSNPAPLNNGSPCPG---DWEQKVPCTTVCPEKPG------QDVKDIALYVGVSLAVLVLATIIVIIIFMIRRK------DQRQFDMDLGERSLPQYD-------DEDKKPAKNGAMVQPDLTQTIAPVRTHSLYDQPPPNNNHIDAMEKIPMLNGHTHPVEDS-----------PIIDKKSKHLYIQLPGEEKTDSTEKLTLQKSKASLKSSTSGSRPQSE-YDTDNSNRQSVTSN--LLPSNIDVEALAWGNITHAGGMLTIPETGVSVSIPEGAISKGNTEEIFIAVCRDDKDRPKLSDKQTILSPILLLGPQGLALHKPVIVSFQHCASQKHGLWVMRVYG-----SGTAYDEP---PAWKHLVTFGEETLNTPIYCQVDTNCCHMMTDQLCRYALIGESMQGTAAMKRLRLAAFAPAVASSI---DYSIRVYVVEDTQDAVEGVIQLEKKLGAALLDRPKQILFQDGGNNLCLTIEELAPGWRSKLTANYQEIPFRHIWSGNQN-NLHCSFSLEHTDGLQQTVSCKIGVYQKSILGNRAVLQIV------SNLTEKVIPSPTVPGKPRASTTVSSSGCSSMVTLDQAQKAFRLPSQIKTKLCAYLDPPNSRGNDWRMLAQALCVDRYINFFASKPSPTEHILDLWEARHREETALTDLMNTLRVMDRFDAAAVLEKELG 919
BLAST of Netrin receptor UNC5B vs. TrEMBL
Match: A0A1S3JPZ4 (netrin receptor UNC5C-like isoform X3 OS=Lingula unguis OX=7574 GN=LOC106174972 PE=4 SV=1) HSP 1 Score: 408.297 bits (1048), Expect = 4.435e-122 Identity = 297/998 (29.76%), Postives = 474/998 (47.49%), Query Frame = 2
Query: 350 PSFIKEPESVYYVYEKKPAKIVCIAEPVSHVNIICNKEVFSYMDLELSESNLRVRKMNKNNEDDLTNGHRWMFSLEITYNQVTEWF--NTFSCVCEAWNQIPSLRLA--------KKVHSRYGVIKEAYFKSNFKKVPQSKTVVKGQSLILTCVPPESKPKAQVQWMKNKKRL--FENNRIKIVEEHQLLIEDTLLTDSGNYSCIAISLEEKRYSPIA--IVKIQES-----------------------VTENPA----------------------------TQWSAWSACDGNCKKTRTRNC------NSKGVCKEID----SCTKKECEYNRAVAPFVKNPNKNGVSTSSLQDARDIAMYVGLFVAVTILVMVITIIFCLIRRKALLPLRSTMRYPLNINGNGV-AYDVKNSLIKNSNTISTKNPYIMDTSLANL---TQQRSYLSQSPPNLPPPTCLSEISSTNAYSTGIDFSYNSTGSGKFSQPLIXXXXXXXXXXXXXXXXXXXXDH---KPDPLTVSGTPINSRPPSALYHELSLDRESICNSPPFVSENIDISTLAWGTISTIGGRLCLPQSGITLTIAPGSFINSSSSEMYLAVSRNDPNPPILSDNETLLTPIVLFGPKDVPILKPCVLSVPHSADLRQGNWVIRLLSCVLPDQNDELKEPLCQPIWKNIATIGCETDQTPIYTHLDPYAAFIMLDQPQKICLVGQSYPGGKATKRLRLAAFGRPLSTSSYLPNYNIRIYVFSDTKEAFESVSTIETKLGSTLLDITYQIIFSDSMGNLFFCIEELSTGWKSQLTTKYQEIPFQDIWSGSQSETLHCAFTFDNIDPSQQSLTCRITAYQSGFYNQKQVITIKQDKLDRSNHKRDLIQHEKVLLYSESNNTY----------LDPLMTVFRISNATRKKLCFLLDNVTPRGNDWKQLCRQLSLNGYLNYFMSKVSPTDALVTLWESRNRNENALIDLIISLKAIGRTDCSTLLESDCG 3067
P F++EPE Y+ + KP I C A + C +E ++ L+ R + + T S+E+T V E+F + + C C AW +IPS V SR G+++ A+ + F++ P S +V + + L C+PP P +V W+K+ + + E I E L+I L+D GN++C AI++ R S A IV ++ + NPA + W++WS C+ +CK R R C N+ C+ D +CT C + + K G QD +DIA+YVG+ +AV +L +I II +IRRK ++ +++ + YD + + KN ++ L + S Q PPN + +I N ++ ++ S P+I S +T+ + ++ + SRP S Y + +R+S+ ++ + NID+ LAWG I+ GG L +P++G++++I G+ ++ E+++AV R+D + P LSD +T+L+PI+L GP+ + + KP ++S H A + G WV+R+ EP P WK++ T G ET TPIY +D +M DQ + L+G+S G A KRLRLAAF +++S +Y+IR+YV DT++A E V +E KLG+ LLD QI+F D NL IEEL+ GW+S+LT YQEIPF+ IWSG+Q+ LHC+F+ ++ D QQ+++C+I YQ + V+ I SN +I V ++ T LD FR+ + + KLC LD RGNDW+ L + L ++ Y+N+F SK SPT+ ++ LWE+R+R E AL DL+ +L+ + R D + +LE + G
Sbjct: 50 PIFLQEPEPHNYIVKSKPVTITCQAINAVDITFRCAEE---WVPLK--------RHVRADFTHPETGEAVLQASVEVTRQAVEEYFGIDGYWCECNAWTEIPSPDRPWTGDNPPPAHVSSRRGLVQVAFIRKRFEREPISTSVELEKPVQLHCLPPTGVPPPEVFWLKDGQVINDKEETNFIISNEGNLIISQARLSDQGNFTCGAINVAATRKSESAELIVYVKGAWSTWSQWSDCDSKCGKGFQSRSRTCSNPAPLNNGSPCPGDWEQKVPCTTVCPVDGGWSTWASWSTCNEDCKHFRRRRCDNPPPQNNGKHCESTDLNITNCTGGLCREFPGSDVYAERTEKPG------QDVKDIALYVGVSLAVLVLATIIVIIIFMIRRK------DQRQFDMDLGERSLPQYD-------DEDKKPAKNGAMVQPDLTQTIAPVRTHSLYDQPPPNNNHIDAMEKIPMLNGHTHPVEDS-----------PIIDKKSKHLYIQLPGEEKTDSTEKLTLQKSKASLKSSTSGSRPQSE-YDTDNSNRQSVTSN--LLPSNIDVEALAWGNITHAGGMLTIPETGVSVSIPEGAISKGNTEEIFIAVCRDDKDRPKLSDKQTILSPILLLGPQGLALHKPVIVSFQHCASQKHGLWVMRVYG-----SGTAYDEP---PAWKHLVTFGEETLNTPIYCQVDTNCCHMMTDQLCRYALIGESMQGTAAMKRLRLAAFAPAVASSI---DYSIRVYVVEDTQDAVEGVIQLEKKLGAALLDRPKQILFQDGGNNLCLTIEELAPGWRSKLTANYQEIPFRHIWSGNQN-NLHCSFSLEHTDGLQQTVSCKIGVYQKSILGNRAVLQIV------SNLTEKVIPSPTVPGKPRASTTVSSSGCSSMVTLDQAQKAFRLPSQIKTKLCAYLDPPNSRGNDWRMLAQALCVDRYINFFASKPSPTEHILDLWEARHREETALTDLMNTLRVMDRFDAAAVLEKELG 985
BLAST of Netrin receptor UNC5B vs. TrEMBL
Match: A0A267FQL3 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig019529g1 PE=4 SV=1) HSP 1 Score: 363.999 bits (933), Expect = 3.743e-105 Identity = 298/1071 (27.82%), Postives = 470/1071 (43.88%), Query Frame = 2
Query: 329 ESKLEGIPSFIKEPESVYYVYEKKPAKIVCIAEPVSHVNIICNKEVFSYMDLELSESNLRVRKMNKNNE--DDLTNGHRWMFSLEITYNQVTEWFNT-FSCVCEAWNQIPSLR-LAKKVHSRYGVIKEAYFKSN-FKKVPQSKTV-VKGQSLILTCVPPESKPKAQVQWMKNKKRL---FENNRIKIVEEHQ-----LLIED-------------TLLTDSGNY-------------------SCIAISLEEKRYSPIAIVKIQESVTENPA----------------------------TQWSAWSACDGNCKKTRTRNCNS-----------------KGVCKEIDSCTKKE-CEYNRAVAPFVKNPNKN---GVSTSSLQDARDIAMYVGLFVAVTILVMVITIIFCLIRRKA--LLPLRSTMRYPLNINGN-------GVAYDVKNSL-------------IKNSNTI------------STKNPYIMDTSLANLTQQRSYLSQSPPNLPPPT-------CLSEISSTNAYSTGIDFSYNSTGSGKFSQPLIXXXXXXXXXXXXXXXXXXXXDHKPDPLTVSGTPINSRPPSALYHE----LSLDRESICNSPPFVSENIDISTLAWGTISTIGGRLCLPQSGITLTIAPGSFINSSSSEMYLAVSRNDPNPPILSDNETLLTPIVLFGPKDVPILKPCVLSVPHSADLRQGNWVIRLL-SCVLPDQNDELKEPLCQPI--WKNIATIGCETDQ-TPIYTHLDPYAAFIML--DQPQKICLVGQSYPGGKATKRLRLAAFGRPLSTSSYLPNYNIRIYVFSDTKEAFESVSTIETKLGSTLLDITYQIIFSDSM-----------GNLFFCIEELSTGWKSQLTTKYQEIPFQDIWSGSQSETLHCAFTFDNIDPSQQSLTCRITAYQSGFYNQKQVITIKQDKLDRSNHKRDLIQHEKVLLYSESNNTYLDPLMTVFRISNATRKKLCFLLDNVTPRGNDWKQLCRQLSLNGYLNYFMSKVSPTDALVTLWESRNRNENALIDLIISLKAIGRTDCSTLLESDCGS 3070
E L G P F+++P VYYV PA I C A+ +V + CN R +NK E D R F + +N V +W ++ + C CEAW +IP+L+ +KV S G ++ AYF+S+ F+ P ++V + + L+C PP+ PK +V+W+K+ K L +++RI I + Q L ++D TL + S SC E R A + +E ++PA QWS W+ C +C +R R C+S +E +C++ C+ + A ++N ++ G +T S ++A+Y+GL A ++V+++ +I +RRK+ R +RY +++NGN G + + L IKN N + + P S +L QQ++ Q P LP + C SS YS G GSG + L+ G SRP SALYHE L + C P ++ + AWGT+ GGRLCLP+SG+TLT+ PG+ + +++LAV R++ + P L TLL+ V GP V + +P +LS+PHSA LR G W + ++ C P ++ + W+ +G E+ P Y LD + L + + CLVGQS GG A K+LR+AAF +S+ S +R++ DT +A +V E G L+D Q++F D++ L +E+LS GW+ + T+ E+PF +WS LHC+ + + +DP++ +++C + YQ+G Y+ + V+ + R L+ S + +DPL VFR+ R L LLD + R NDW+QL R L L+ + YF +K SP++ L+ LWE+R R AL DL +LKA+GR D ++L+E G+
Sbjct: 50 EQLLPGAPRFVEQPRPVYYVTRSTPASIECAADQAMYVTVHCNG-----------------RALNKKVEVASDHERPERQRFHALVDFNDVRDWSSSSYYCNCEAWGKIPALKNELRKVISSSGYVRLAYFESDRFQFDPMPRSVPLDASEVTLSCTPPKGSPKPKVKWLKDGKPLDVRSQSDRITIDHQAQLIIRPLRLDDRGNYSCLAEIPGLTLASGSAELNIYVNGGWSHWSQWLGCDPSCDETVSPECRAECAAQQRTRERRCDSPAPAFNGQPCHGAARETAPCNAKCAVHGQWGQWSQWTQCSSDCLSSRQRRCDSPPPSGPGGRPCPGIASSSAAGQEWRNCSEGRLCKRDNAALLMLRNDGQSQGSGSATDSGVGLANLAIYIGLVAAAAVVVIIVLVIVYFVRRKSATFGSNRQGLRYNVHMNGNSSVSSSAGKEAQITHELLLPASSGPSGGCSIKNGNGVMLEMSAAAAAPAPSGMPMPSLGSYQHLQQQQALRVQLP--LPQMSYLQQQQCCPRPASSIGVYSNG-----QLDGSGASN------------------------------LSPGGGSSLSRPCSALYHEPASLLGGHVTAACVPPGLSADQV-----AWGTVGPAGGRLCLPESGVTLTVPPGAVTSPHGEDLFLAVCRDERDHPSLDGRRTLLSSTVACGPASVSLARPAILSLPHSASLRHGFWNVAVMRRCCEPPSSESAADASTDSAGSWREFLRVGSESAALAPAYCQLDAADSLCHLVTESLGRFCLVGQSLDGGCAVKQLRVAAF---VSSGSGGSELAVRLHALPDTGDALAAVLAAERSSGWRLVDEPRQLLFRDALPQQQQQQQQQQSALCCSVEDLSLGWRCR--TRRVEVPFGHVWSCGPG-GLHCSLSLEQVDPTRMAVSCSLAVYQAGAYSARLVLRL---ACSRGEQPGLLMSSHSASPISSTCLPVVDPLQPVFRLQPKLRAALSRLLDAPSARANDWRQLARLLGLDRQVGYFAAKPSPSECLLDLWEARCRGPGALADLAEALKAMGRRDAASLVEQGPGA 1052
BLAST of Netrin receptor UNC5B vs. TrEMBL
Match: K1QEZ7 (Netrin receptor UNC5C OS=Crassostrea gigas OX=29159 GN=CGI_10026060 PE=4 SV=1) HSP 1 Score: 360.533 bits (924), Expect = 3.842e-105 Identity = 283/939 (30.14%), Postives = 437/939 (46.54%), Query Frame = 2
Query: 593 VTEWFNT-FSCVCEAWNQIPSLRLAKKVHSRYGVIKEAYFKSNFKKVPQSKTVVKGQSLILTCVPPESKPKAQVQWMKNKKRLFENNRIKIVEE-HQLLIEDTLLTDSGNYSCIAISLEEKRYSPIA--IVKIQ-----------------------------------------ESVTENPATQ----------WSAWSACDGNCKKTRTRNCN--------SKGVCKEIDS--CTKKECEYNR-------------AVAP-----------------FVKNPNKNGVSTSSLQDARDIAMYVGLFVAVTILVMVITIIFCLIRRKALLPLRSTMRYPLNINGNGVAYDVKNSLIKNSNTISTKNPYIMDTSLANLTQQR---SYLSQSP-PNLPPPTCLSEISSTNAYSTGIDFSYNSTGSGKFSQPLIXXXXXXXXXXXXXXXXXXXXDHKP---DPLTVSGTPINSRPPSALYHELSLDRESICNSPPFVSENIDISTLAWGTISTIGGRLCLPQSGITLTIAPGSFINSSSSEMYLAVSRNDPNPPILSDNETLLTPIVLFGPKDVP--ILKPCVLSVPHSADLRQGNWVIRLLSCVLPDQNDELKEPLCQPIWKNIATIGCETDQTPIYTHLDPYAAFIMLDQPQKICLVGQSYPGGKATKRLRLAAFGRPLSTSSYLPNYNIRIYVFSDTKEAFESVSTIETKLGSTLLDITYQIIFSDSMGNLFFCIEELSTGWKSQLTTKYQEIPFQDIWSGSQSETLHCAFTFDNIDPSQQSLTCRITAYQSGFYNQKQVITIK----QDKLDRSNHKRDLIQHEKVLLYSESNNTY-----LDPLMTVFRISNATRKKLCFLLDNVTPRGNDWKQLCRQLSLNGYLNYFMSKVSPTDALVTLWESRNRNENALIDLIISLKAIGRTDCSTLLESDCGS 3070
V E+F F C C A+N L + S+ G I+ AY + F++ P V ++ L C+PPE KP +V W+K+ + + IV LLI T L D GNY+C A +L +R S A IV + +SV NP WS+WS C C+ R R CN S + ++D CT C + A AP +NP++ +TS+ D + M +GL +AV + V+VI I+ L++RK ++ NI G A + KN KN M + +LTQQ + S SP P++ PP N Y T + + +P + A + + ++ P PL ++ P N PP+ L S+ + N + + WG+ + GGRL LP+SG+ +TI G+ +E+YL V R+D N P SD +T+++P+++ GP +VP ++KP +LS H A +RQG W++ L + +P P W+ + T+G ET T +Y LDP +M + Q L+G++ PGG+ K LRLAAF S + ++IR+YV DT +A E V E K G LLD QI F D NL IEEL+ GW+S+L YQEIPFQ IWSG+Q+ LHC+F+ + ++ S +++C+I YQ + +QV+ I+ ++KL + ++ + + S++ + LDP FR+ R+KLC LLD RGNDW+ L + L+++ Y+ YF +K SPT+ ++ LWE+R+R E+A+ DL+ + +GR D + ++E D G+
Sbjct: 30 VEEYFGGDFWCECFAYNTNIGLDGVGGIRSKQGTIEIAYLRKRFEREPLMTRVQVSKTTQLDCLPPEGKPLPEVFWLKDNVEINTKDGYYIVSNTGDLLISQTQLRDMGNYTCGAKNLAARRLSESASLIVYVDGSWSSWSSWTECSVKCGKGETRRMRTCTNPAPLNGGATCVGDSVQTNPCGSICPVDGRWGAWSSWSTCSTECQHHRKRYCNDPPAKDGGSYCIGNDLDGGNCTGGRCRGKQIEIIGPSPTNPTNADAPNPDDVRGIGIEDADHGLLEQNPSREATNTSTNNDT--LIMIIGLCIAVVVFVVVIAIVVFLLKRK----YQNQGYMAGNIPPIGNAEEKKN-----------KNGQDMMSVQPDLTQQVVVFPHHSASPSPSIEPPN--------NNYPTVENI---------YDKPDVGLPIYADHRLSNGSVPNRSSPELPPPNSPLVMNLVPPN--PPNLLDSRHSMSSVQL-------PANAETEAVTWGSFNHSGGRLILPESGVCMTIPEGAVKKGHEAELYLGVWRDDTNRPKTSDGQTIVSPVIVCGP-NVPGILMKPIILSFHHCASMRQGGWMLSLF--------NSDTQPEEAPCWQKLVTLGQETINTQVYAQLDPNQCHVMTEHMQWYTLIGEAVPGGRPVKILRLAAFA---SNTPPSVEFSIRVYVVEDTHDALEGVMQEERKFGGRLLDKPKQIPFQDGGHNLCLTIEELTPGWRSKLAANYQEIPFQHIWSGNQN-NLHCSFSLELVEGSSPNVSCKIQVYQKAILSNRQVLNIQNNFNKEKLPSCSTPSSTLKGRTSTVTTNSSSGFSSMLTLDPHGNNFRLPPHIRQKLCLLLDQPNARGNDWRMLAQALTVDRYVQYFATKSSPTEHILNLWEARHREESAITDLMNIFRVMGRMDAAAVMEKDIGA 912
BLAST of Netrin receptor UNC5B vs. Ensembl Cavefish
Match: unc5c (unc-5 netrin receptor C [Source:ZFIN;Acc:ZDB-GENE-030131-9196]) HSP 1 Score: 335.495 bits (859), Expect = 2.926e-99 Identity = 273/967 (28.23%), Postives = 438/967 (45.29%), Query Frame = 2
Query: 341 EGIPSFIKEPESVYYVYEKKPAKIVCIAEPVSHVNIICNKEVFSYMDLELSE-----SNLRVRKMNKNNEDDLTNGHRWMFSLEITYNQVTEWFN--TFSCVCEAWNQIPSLRLAKKVHSRYGVIKEAYFKSNFKKVPQSKTVVKGQSLILTCVPPESKPKAQVQWMKNKKRL--FENNRIKIVEEHQLLIEDTLLTDSGNYSCIAISLEEKRYSPIAIVKIQESVTENPATQWSAWSACDGNCKK---TRTRNC------NSKGVCKE-------------ID---------SCTKKECEYNR---AVAPFVKNPNKN-------------GVSTSSLQDARDIAMYVGLFVAVTILVMVITIIFCLIRRKALLPLRSTMRYPLNINGNGVAYDVKNSLIKNSNTISTKNPYIMDTSLANLTQQRSYLSQSPPNLPPPTCLSEISSTNAYSTGIDFSYNSTGSG--KFSQPLIXXXXXXXXXXXXXXXXXXXXDHKPDPLTVSGTPINSRPPSALYHELSLDRESICNSPPFVSENIDISTLAWGTISTIGGRLCLPQSGITLTIAPGSFINSSSSEMYLAVSRNDPNPPILSDNETLLTPIVLFGPKDVPILKPCVLSVPHSADLRQGNWVIRLLSCVLPDQNDELKEPLCQPIWKNIATIGCETDQTPIYTHLDPYAAFIMLDQPQKICLVGQSYPGGKATKRLRLAAFGRPLSTSSYLPNYNIRIYVFSDTKEAFESVSTIETKLGSTLLDITYQIIFSDSMGNLFFCIEEL-STGWKSQLTTKYQEIPFQDIWSGSQSETLHCAFTFDNIDPSQQSLTCRITAYQSGFYNQKQVITIKQDKLDRSNHKRDLIQHEKVLLYSESN-NTYLDPLMTVFRISNATRKKLCFLLDNVTPRGNDWKQLCRQLSLNGYLNYFMSKVSPTDALVTLWESRNRNENALIDLIISLKAIGRTDCSTLLESD 3061
E +P F+ EPE Y V + KP + C A P + + CN E + + E S L VR+ S+EIT QV E F F C C AW+ A SR ++ AY + F + P K V Q ++L C PPE P A+V+W+KN++ + E+ I +H L+I+ L+D+ NY+C+A ++ KR S A V + + W+ WSAC+ C + RTR+C N +C+ +D S EC + R AP KN K+ G+ + D+A+YVG+ +AV I+ +VI++I AL R R D + +I +S P + T+ + + L +PP+L +S A G ++ + + PL+ + + + ++ + D +S+ L H L +D +++ + + D S A+G+ +++GG L +P SG++L + G+ EMY+ V R + P + D +T+L+P+V GP + +P ++++ H A+ +W+I+L S Q+ Q W+++ +G E TP Y +D A I+ + CLVGQS TKRL+LA FG P++ ++ YNIR+Y DT++A + V +E ++G LLD + F DS NL + ++ T WKS+L KYQE+ FQ +WSGSQ LHC FT + L C++ Q + Q+ + + D + LL SN T + P FRI + R+KLC LD RGNDW+ L +L+L+ YLNYF +K SPT ++ LWE+++ + L L L+ +GR + T + ++
Sbjct: 55 EPLPHFLMEPEEAYIV-KNKPVNLYCKATPATQIYFKCNSEWVHQKEHTVEERVDETSGLVVREA----------------SIEITRQQVEELFGLEDFWCQCVAWSS------AGTTKSRKAHVRIAYLRKTFDQEPLGKEVSLEQEVLLQCRPPEGIPAAEVEWLKNEEVIDPAEDRNFYITIDHNLIIKQARLSDTANYTCVAKNIVAKRRSTTATVIV---YVNGGWSTWTEWSACNSRCGRGFQKRTRSCTNPAPLNGGAICEGQPIQKLACNPLCPVDGLWTEWSKWSTCGTECTHWRRRECSAPAPKNGGKDCEGMVLQSKNCTDGLCMQTAPSTDDVALYVGIVIAV-IMCLVISVIV------ALFVYRKNHR------------DFDSDIIDSSALNGGFQPVSIKTA------RTADLLAAPPDL---------TSAAAMYRGPVYALHDVADKIPMTNSPLLDPLPNLKIKVYNSSGLVTPQEDLSD--------FSSKLSPKLPHSL-IDSDTMGRRTQSLVRSRDPSCTAFGSFNSLGGHLIVPNSGVSLLVPAGAIPQGRVYEMYVTVHRKETMRPSVDDTQTVLSPVVSCGPPGALLTRPVIITMHHCAEADSEDWLIQLRS-----QSQ-------QGQWEDVVVVGEENFTTPCYIQMDEEACHILTETLGTYCLVGQSV-SAATTKRLKLAVFG-PVTCTAL--EYNIRVYCLDDTQDALKEVLQMEKQMGGKLLDEPKTLNFKDSTHNLRLSLHDVPHTLWKSKLLAKYQELSFQHVWSGSQ-RNLHCTFTLERFSAGTLELGCKLCVRQ--VEGEGQIFQLN------TTLSEDSQCIDTSLLDPASNITTLVGP--NAFRIPLSIRQKLCSSLDAPQTRGNDWRMLAHKLNLDRYLNYFATKSSPTGVILDLWEAQHFPDGNLNRLAAVLEEMGRHENITAMPAE 925
BLAST of Netrin receptor UNC5B vs. Ensembl Cavefish
Match: unc5b (unc-5 netrin receptor B [Source:NCBI gene;Acc:103042383]) HSP 1 Score: 218.779 bits (556), Expect = 1.172e-58 Identity = 131/423 (30.97%), Postives = 217/423 (51.30%), Query Frame = 2
Query: 1796 AWGTISTIGGRLCLPQSGITLTIAPGSFINSSSSEMYLAVSRNDPNPPILSDNETLLTPIVLFGPKDVPILKPCVLSVPHSADLRQGNWVIRLLSCVLPDQNDELKEPLCQPIWKNIATIGCETDQTPIYTHLDPYAAFIMLDQPQKICLVGQSYPGGKATKRLRLAAFGRPLSTSSYLPNYNIRIYVFSDTKEAFESVSTIETKLGSTLLDITYQIIFSDSMGNLFFCIEEL-STGWKSQLTTKYQEIPFQDIWSGSQSETLHCAFTFDNIDPSQQSLTCRITAYQSGFYNQKQVITIKQDKLDRSNHKRDLIQHEKVLLYSESNNTYLDPLMTVFRISNATRKKLCFLLDNVTPRGNDWKQLCRQLSLNGYLNYFMSKVSPTDALVTLWESRNRNENALIDLIISLKAIGRTDCSTLLESD 3061
A T+ +GGRL +P +G++L + PG+ EMYL +++ + +T+L+P+V GP + + +P +L++PH A L +W S L Q ++ W+ + T+G E+ +P Y ++ ++++Q LVGQS P A KRL+LA F P + L +Y++R+Y DT A + V +E LG LL+ ++F DS NL I ++ + W+S+L KYQEIPF IWSGSQ LHC F+ + + L+C+I Q + Q+ + D + + + L S Y FR+ + R+K+C LD + RG DW+ L L + YLNYF +K SPT L+ LWE+ ++ + L+ L +L+ +G+++ ++ +D
Sbjct: 484 ASATLGCLGGRLAIPNTGVSLLVPPGTIPQGKFYEMYLIINKWEKTTLPSEGGQTVLSPVVSCGPSGMLLSRPVILTLPHCAQLEPPDW-----SLTLKTQTNQ--------AWEEVLTVGEESLSSPCYLQVEEQNCHVLMEQLGTYGLVGQSVPPQPACKRLQLALFA-PRAPCLSL-DYSLRVYCIHDTPHALKEVLELERSLGGVLLEDPKPLLFKDSYHNLRLSIHDIPHSHWRSKLLAKYQEIPFYHIWSGSQ-RPLHCTFSLERGSLAVSQLSCKICVRQ--VEGEGQIFQLHTD-IQETLPPHSPLPAGGTCLPSSQVGPY------AFRLPASIRQKICASLDAPSARGCDWRLLAHSLGFDRYLNYFATKPSPTGVLLDLWEACHQGDADLVSLATALEEMGKSEVLVVMTTD 881 HSP 2 Score: 127.872 bits (320), Expect = 1.576e-29 Identity = 86/339 (25.37%), Postives = 153/339 (45.13%), Query Frame = 2
Query: 260 IFGVKGNQPTREIEDENDFVKLNESKLEGIPSFIKEPESVYYVYEKKPAKIVCIAEPVSHVNIICNKEVFSYMDLELSESNLRVRKMNKNNEDDLTNGHRWMFSLEITYNQVTEWFN--TFSCVCEAWNQIPSLRLAKKVHSRYGVIKEAYFKSNFKKVPQSKTVVKGQSLILTCVPPESKPKAQVQWMKNKKRL--FENNRIKIVEEHQLLIEDTLLTDSGNYSCIAISLEEKRYSPIAIVKIQESVTENPATQWSAWSACDGNCKKTRTRNCNSK----------GVCKEIDSCTKKECEYNRAVAPFVKNPNKNGVSTSSLQDARDIAMYVGLFVA 1234
++G G+ + + D + E +P F EPE + V + +P K+ C A P + + CN E + D + + + D +T + ++ QV E F + C C AW+ A SR ++ AY + NF++ P + V Q ++L C PPE P A+V+W+KN+ + +++ + +H L+I+ L+D+ NY+C+A ++ KR S A + + + T+W+ WSAC C R+R C + G E +CT+ C N+ ++ +++ +T L +A+Y GL A
Sbjct: 26 VYGADGSDYSEVLPD-----SFPSAPAEPLPEFQSEPEDAFIV-KNRPVKLSCKAAPATQIYFKCNGEWVNQND-----------HVTRESLDQITGLVVREVDISVSRTQVEELFGLEDYWCQCVAWSS------AGTTKSRRAYVRIAYLRKNFEQEPLGREVRLEQEVLLQCRPPEGIPPAEVEWLKNEDLIDPTQDSNFLMTVDHDLIIKQARLSDTANYTCVARNVVAKRRSSTATLIV---YVDGGWTEWAKWSACGTECTHWRSRECQAPPPRNGGRHCIGSIMESKNCTEGLCARNKKIS--IEH------TTHPLDSGAGVAVYAGLVGA 330
BLAST of Netrin receptor UNC5B vs. Ensembl Cavefish
Match: unc5b (unc-5 netrin receptor B [Source:NCBI gene;Acc:103042383]) HSP 1 Score: 218.779 bits (556), Expect = 2.038e-58 Identity = 131/423 (30.97%), Postives = 217/423 (51.30%), Query Frame = 2
Query: 1796 AWGTISTIGGRLCLPQSGITLTIAPGSFINSSSSEMYLAVSRNDPNPPILSDNETLLTPIVLFGPKDVPILKPCVLSVPHSADLRQGNWVIRLLSCVLPDQNDELKEPLCQPIWKNIATIGCETDQTPIYTHLDPYAAFIMLDQPQKICLVGQSYPGGKATKRLRLAAFGRPLSTSSYLPNYNIRIYVFSDTKEAFESVSTIETKLGSTLLDITYQIIFSDSMGNLFFCIEEL-STGWKSQLTTKYQEIPFQDIWSGSQSETLHCAFTFDNIDPSQQSLTCRITAYQSGFYNQKQVITIKQDKLDRSNHKRDLIQHEKVLLYSESNNTYLDPLMTVFRISNATRKKLCFLLDNVTPRGNDWKQLCRQLSLNGYLNYFMSKVSPTDALVTLWESRNRNENALIDLIISLKAIGRTDCSTLLESD 3061
A T+ +GGRL +P +G++L + PG+ EMYL +++ + +T+L+P+V GP + + +P +L++PH A L +W S L Q ++ W+ + T+G E+ +P Y ++ ++++Q LVGQS P A KRL+LA F P + L +Y++R+Y DT A + V +E LG LL+ ++F DS NL I ++ + W+S+L KYQEIPF IWSGSQ LHC F+ + + L+C+I Q + Q+ + D + + + L S Y FR+ + R+K+C LD + RG DW+ L L + YLNYF +K SPT L+ LWE+ ++ + L+ L +L+ +G+++ ++ +D
Sbjct: 540 ASATLGCLGGRLAIPNTGVSLLVPPGTIPQGKFYEMYLIINKWEKTTLPSEGGQTVLSPVVSCGPSGMLLSRPVILTLPHCAQLEPPDW-----SLTLKTQTNQ--------AWEEVLTVGEESLSSPCYLQVEEQNCHVLMEQLGTYGLVGQSVPPQPACKRLQLALFA-PRAPCLSL-DYSLRVYCIHDTPHALKEVLELERSLGGVLLEDPKPLLFKDSYHNLRLSIHDIPHSHWRSKLLAKYQEIPFYHIWSGSQ-RPLHCTFSLERGSLAVSQLSCKICVRQ--VEGEGQIFQLHTD-IQETLPPHSPLPAGGTCLPSSQVGPY------AFRLPASIRQKICASLDAPSARGCDWRLLAHSLGFDRYLNYFATKPSPTGVLLDLWEACHQGDADLVSLATALEEMGKSEVLVVMTTD 937 HSP 2 Score: 113.62 bits (283), Expect = 3.779e-25 Identity = 73/278 (26.26%), Postives = 129/278 (46.40%), Query Frame = 2
Query: 260 IFGVKGNQPTREIEDENDFVKLNESKLEGIPSFIKEPESVYYVYEKKPAKIVCIAEPVSHVNIICNKEVFSYMDLELSESNLRVRKMNKNNEDDLTNGHRWMFSLEITYNQVTEWFN--TFSCVCEAWNQIPSLRLAKKVHSRYGVIKEAYFKSNFKKVPQSKTVVKGQSLILTCVPPESKPKAQVQWMKNKKRL--FENNRIKIVEEHQLLIEDTLLTDSGNYSCIAISLEEKRYSPIAIVKIQESVTENPATQWSAWSACDGNCKKT---RTRNCN 1072
++G G+ + + D + E +P F EPE + V + +P K+ C A P + + CN E + D + + + D +T + ++ QV E F + C C AW+ A SR ++ AY + NF++ P + V Q ++L C PPE P A+V+W+KN+ + +++ + +H L+I+ L+D+ NY+C+A ++ KR S A + + S + W+ WS C+ C + RTR+C
Sbjct: 26 VYGADGSDYSEVLPD-----SFPSAPAEPLPEFQSEPEDAFIV-KNRPVKLSCKAAPATQIYFKCNGEWVNQND-----------HVTRESLDQITGLVVREVDISVSRTQVEELFGLEDYWCQCVAWSS------AGTTKSRRAYVRIAYLRKNFEQEPLGREVRLEQEVLLQCRPPEGIPPAEVEWLKNEDLIDPTQDSNFLMTVDHDLIIKQARLSDTANYTCVARNVVAKRRSSTATLIVYVS---GGWSSWTEWSECNARCGRGWQRRTRSCT 277
BLAST of Netrin receptor UNC5B vs. Ensembl Cavefish
Match: unc5b (unc-5 netrin receptor B [Source:NCBI gene;Acc:103042383]) HSP 1 Score: 218.009 bits (554), Expect = 2.933e-58 Identity = 131/423 (30.97%), Postives = 217/423 (51.30%), Query Frame = 2
Query: 1796 AWGTISTIGGRLCLPQSGITLTIAPGSFINSSSSEMYLAVSRNDPNPPILSDNETLLTPIVLFGPKDVPILKPCVLSVPHSADLRQGNWVIRLLSCVLPDQNDELKEPLCQPIWKNIATIGCETDQTPIYTHLDPYAAFIMLDQPQKICLVGQSYPGGKATKRLRLAAFGRPLSTSSYLPNYNIRIYVFSDTKEAFESVSTIETKLGSTLLDITYQIIFSDSMGNLFFCIEEL-STGWKSQLTTKYQEIPFQDIWSGSQSETLHCAFTFDNIDPSQQSLTCRITAYQSGFYNQKQVITIKQDKLDRSNHKRDLIQHEKVLLYSESNNTYLDPLMTVFRISNATRKKLCFLLDNVTPRGNDWKQLCRQLSLNGYLNYFMSKVSPTDALVTLWESRNRNENALIDLIISLKAIGRTDCSTLLESD 3061
A T+ +GGRL +P +G++L + PG+ EMYL +++ + +T+L+P+V GP + + +P +L++PH A L +W S L Q ++ W+ + T+G E+ +P Y ++ ++++Q LVGQS P A KRL+LA F P + L +Y++R+Y DT A + V +E LG LL+ ++F DS NL I ++ + W+S+L KYQEIPF IWSGSQ LHC F+ + + L+C+I Q + Q+ + D + + + L S Y FR+ + R+K+C LD + RG DW+ L L + YLNYF +K SPT L+ LWE+ ++ + L+ L +L+ +G+++ ++ +D
Sbjct: 524 ASATLGCLGGRLAIPNTGVSLLVPPGTIPQGKFYEMYLIINKWEKTTLPSEGGQTVLSPVVSCGPSGMLLSRPVILTLPHCAQLEPPDW-----SLTLKTQTNQ--------AWEEVLTVGEESLSSPCYLQVEEQNCHVLMEQLGTYGLVGQSVPPQPACKRLQLALFA-PRAPCLSL-DYSLRVYCIHDTPHALKEVLELERSLGGVLLEDPKPLLFKDSYHNLRLSIHDIPHSHWRSKLLAKYQEIPFYHIWSGSQ-RPLHCTFSLERGSLAVSQLSCKICVRQ--VEGEGQIFQLHTD-IQETLPPHSPLPAGGTCLPSSQVGPY------AFRLPASIRQKICASLDAPSARGCDWRLLAHSLGFDRYLNYFATKPSPTGVLLDLWEACHQGDADLVSLATALEEMGKSEVLVVMTTD 921 HSP 2 Score: 98.9821 bits (245), Expect = 1.531e-20 Identity = 70/252 (27.78%), Postives = 116/252 (46.03%), Query Frame = 2
Query: 341 EGIPSFIKEPESVYYVYEKKPAKIVCIAEPVSHVNIICNKEVFSYMDLELSESNLRVRKMNKNNEDDLTNGHRWMFSLEITYNQVTEWFN--TFSCVCEAWNQIPSLRLAKKVHSRYGVIKEAYFK-SNFKKVPQSKTVVKGQSLILTCVPPESKPKAQVQWMKNKKRL--FENNRIKIVEEHQLLIEDTLLTDSGNYSCIAISLEEKRYSPIAIVKIQESVTENPATQWSAWSACDGNCKKT---RTRNCN 1072
E +P F EPE + V + +P K+ C A P + + CN E + D ES ++ + D + ++ QV E F + C C AW+ S Y K SNF++ P + V Q ++L C PPE P A+V+W+KN+ + +++ + +H L+I+ L+D+ NY+C+A ++ KR S A + + S + W+ WS C+ C + RTR+C
Sbjct: 48 EPLPEFQSEPEDAFIV-KNRPVKLSCKAAPATQIYFKCNGEWVNQNDHVTRESLDQITGLVVREVD-----------ISVSRTQVEELFGLEDYWCQCVAWSSAVS----------------TYEKLSNFEQEPLGREVRLEQEVLLQCRPPEGIPPAEVEWLKNEDLIDPTQDSNFLMTVDHDLIIKQARLSDTANYTCVARNVVAKRRSSTATLIVYVS---GGWSSWTEWSECNARCGRGWQRRTRSCT 268
BLAST of Netrin receptor UNC5B vs. Ensembl Cavefish
Match: unc5b (unc-5 netrin receptor B [Source:NCBI gene;Acc:103042383]) HSP 1 Score: 218.009 bits (554), Expect = 3.084e-58 Identity = 131/423 (30.97%), Postives = 217/423 (51.30%), Query Frame = 2
Query: 1796 AWGTISTIGGRLCLPQSGITLTIAPGSFINSSSSEMYLAVSRNDPNPPILSDNETLLTPIVLFGPKDVPILKPCVLSVPHSADLRQGNWVIRLLSCVLPDQNDELKEPLCQPIWKNIATIGCETDQTPIYTHLDPYAAFIMLDQPQKICLVGQSYPGGKATKRLRLAAFGRPLSTSSYLPNYNIRIYVFSDTKEAFESVSTIETKLGSTLLDITYQIIFSDSMGNLFFCIEEL-STGWKSQLTTKYQEIPFQDIWSGSQSETLHCAFTFDNIDPSQQSLTCRITAYQSGFYNQKQVITIKQDKLDRSNHKRDLIQHEKVLLYSESNNTYLDPLMTVFRISNATRKKLCFLLDNVTPRGNDWKQLCRQLSLNGYLNYFMSKVSPTDALVTLWESRNRNENALIDLIISLKAIGRTDCSTLLESD 3061
A T+ +GGRL +P +G++L + PG+ EMYL +++ + +T+L+P+V GP + + +P +L++PH A L +W S L Q ++ W+ + T+G E+ +P Y ++ ++++Q LVGQS P A KRL+LA F P + L +Y++R+Y DT A + V +E LG LL+ ++F DS NL I ++ + W+S+L KYQEIPF IWSGSQ LHC F+ + + L+C+I Q + Q+ + D + + + L S Y FR+ + R+K+C LD + RG DW+ L L + YLNYF +K SPT L+ LWE+ ++ + L+ L +L+ +G+++ ++ +D
Sbjct: 529 ASATLGCLGGRLAIPNTGVSLLVPPGTIPQGKFYEMYLIINKWEKTTLPSEGGQTVLSPVVSCGPSGMLLSRPVILTLPHCAQLEPPDW-----SLTLKTQTNQ--------AWEEVLTVGEESLSSPCYLQVEEQNCHVLMEQLGTYGLVGQSVPPQPACKRLQLALFA-PRAPCLSL-DYSLRVYCIHDTPHALKEVLELERSLGGVLLEDPKPLLFKDSYHNLRLSIHDIPHSHWRSKLLAKYQEIPFYHIWSGSQ-RPLHCTFSLERGSLAVSQLSCKICVRQ--VEGEGQIFQLHTD-IQETLPPHSPLPAGGTCLPSSQVGPY------AFRLPASIRQKICASLDAPSARGCDWRLLAHSLGFDRYLNYFATKPSPTGVLLDLWEACHQGDADLVSLATALEEMGKSEVLVVMTTD 926 HSP 2 Score: 114.005 bits (284), Expect = 3.543e-25 Identity = 73/278 (26.26%), Postives = 129/278 (46.40%), Query Frame = 2
Query: 260 IFGVKGNQPTREIEDENDFVKLNESKLEGIPSFIKEPESVYYVYEKKPAKIVCIAEPVSHVNIICNKEVFSYMDLELSESNLRVRKMNKNNEDDLTNGHRWMFSLEITYNQVTEWFN--TFSCVCEAWNQIPSLRLAKKVHSRYGVIKEAYFKSNFKKVPQSKTVVKGQSLILTCVPPESKPKAQVQWMKNKKRL--FENNRIKIVEEHQLLIEDTLLTDSGNYSCIAISLEEKRYSPIAIVKIQESVTENPATQWSAWSACDGNCKKT---RTRNCN 1072
++G G+ + + D + E +P F EPE + V + +P K+ C A P + + CN E + D + + + D +T + ++ QV E F + C C AW+ A SR ++ AY + NF++ P + V Q ++L C PPE P A+V+W+KN+ + +++ + +H L+I+ L+D+ NY+C+A ++ KR S A + + S + W+ WS C+ C + RTR+C
Sbjct: 26 VYGADGSDYSEVLPD-----SFPSAPAEPLPEFQSEPEDAFIV-KNRPVKLSCKAAPATQIYFKCNGEWVNQND-----------HVTRESLDQITGLVVREVDISVSRTQVEELFGLEDYWCQCVAWSS------AGTTKSRRAYVRIAYLRKNFEQEPLGREVRLEQEVLLQCRPPEGIPPAEVEWLKNEDLIDPTQDSNFLMTVDHDLIIKQARLSDTANYTCVARNVVAKRRSSTATLIVYVS---GGWSSWTEWSECNARCGRGWQRRTRSCT 277
BLAST of Netrin receptor UNC5B vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008404.1 (pep scaffold:Pmarinus_7.0:GL476608:255441:311832:-1 gene:ENSPMAG00000007555.1 transcript:ENSPMAT00000008404.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 246.899 bits (629), Expect = 1.172e-68 Identity = 237/979 (24.21%), Postives = 393/979 (40.14%), Query Frame = 2
Query: 341 EGIPSFIKEPESVYYVYEKKPAKIVCIAEPVSHVNIICNKEVFS----YMDLELSE-SNLRVRKMNKNNEDDLTNGHRWMFSLEITYNQVTEWF--NTFSCVCEAWNQIPSLRLAKKVHSRYGVIKEAYFKSNFKKVPQSKTVVKGQSLILTCVPPESKPKAQVQWMKNKKRL--FENNRIKIVEEHQLLIEDTLLTDSGNYSCIAISLEEKRYSPIAIVKI-------------------------QESVTENPA----------------------------TQWSAWSACDGNCKKTRTRNCNSKGVCKEIDSCTKKECEYNRAVAPFVKNPNKN--GVSTSSL---QDARDIAMYVGLFVAVTILV-MVITIIFCLIRRKALLPLRSTMRYPLNINGNGVAYDVKNSLIKNSNTISTKNPYIMDTSLANLTQQRSYLSQSPPNLPPPTCLSEISSTNAYSTGIDFSYNSTGSGKFSQ-PLIXXXXXXXXXXXXXXXXXXXXDHKPDPLTVSGTPINSRPPSAL--YHELSLDRESICNSPPFVSENIDISTLAWGTISTIGGRLCLPQSGITLTIAPGSFINSSSSEMYLAVSRNDPNPPILSDNETLLTPIVLFGPKDVPILKPCVLSVPHSADLRQGNWVIRLLSCVLPDQNDELKEPLCQPIWKNIATIGCETDQTPIYTHLDPYAAFIMLDQPQKI--CLVGQSYPGGKATKRLRLAAFGRPLSTSSYLPNYNI------RIYVFSDTKEAFESVSTIETKLGSTLLDITYQIIFSDSMGNLFFCIEEL-STGWKSQLTTKYQEIPFQDIWSGSQSETLHCAFTFDNIDPSQQSLTCRITAYQSGFYNQKQVITIKQDKLDRSNHKRDLIQHEKVLLYSESNNTYLDPLMTVFRISNATRKKLCFLLDNVTPRGNDWKQLCRQLSLNGYLNYFMSKVSPTDALVTLWESRNRNENALIDLIISLKAIGRTD 3037
E +P F+ EP + V + KP + C A P + + CN E Y LSE + VR+++ N ++ QV + + F C C AW+ + SR +K A+ + NF++ P K V ++L C PPE+ P A+V+WMK+K+ + E++ I +H L+I+ L+DS NY+C+A +L KR S A V + + NPA +WS WS C +C R+R C++ C + K G STS + + ++A+Y G+ VA+ I V +V+ F L RR+ Y +I D ++L ++ K D S T + L+ S P P + +N+T + +Q PL+ S + S + + S +R P+ + +H L L C + + + T +GT +GGRL + SG++L + PG+ +MY+ + R P L +++TLL+P+V G VP+L P +LS+ H A+L +W + LK L W+ + G E P H + + + C S+ ++ GR + P + + Y S T + F+ V +E +LG LL+ + F + GNL I + W ++L +QEIPF +W G Q LHC F + S +C++ Q + QV+ ++ L+ + D + + + + P F++ + R+KLC LD+ PRGNDW+ L +L +N Y NYF + SPT ++ LWE+++ + L L L+ +GR +
Sbjct: 8 EPLPIFLTEPNDGFIV-QNKPVTLDCSASPATQIYFKCNGEWLHQKALYTQEHLSEITGKVVREVHTN----------------VSRQQVEDPYRLEDFWCQCVAWSA------SGTTKSRKAFVKVAHLRKNFEQEPLGKDVPLNHEVLLHCRPPEAIPPAEVEWMKDKELIDPEEDSNFYITVDHNLIIKQARLSDSANYTCVAKNLVAKRRSSTATVTVYVNGGWSLWTEWSPCNSKCGRGTQKRTRSCTNPAPLNGGAVCNGQGTQKIPCSTICPVDGGWVEWSKWSTCGPDCTHWRSRECSNPAPVNGGKDCHGSPLQSQNCSDALCIQSEKIIIGQSTSCVLASEAGDEVALYAGVAVALVISVGVVLAASFVLYRRR-------RQEYGSDI------IDSASALTGGFRPVNQKAGRNADDSNLLRTAIQPDLTASVGTFPQP---------------VYPVHNATQKIQMTQSPLLEPLPGHKIKVCSSSMLASTDNEGDQSVEPSPKRHGTRQPNKMIQHHTLDLAPTETCLDNNEMHQ-VGSDTTVFGTFCCLGGRLTIAHSGVSLLVPPGAIPPGQFYQMYITIHREKEKRPALENSQTLLSPVVSCGAPSVPLLSPVILSLRHCAELSPEDWAL------------SLKRQLSSGPWEEVLRQG-EEPARPPSCHWQRVSVSVTSTTAHLVSFCYYCSSF----------MSVCGRVCHQDYFSPCLCVCGRVCHQYYCSSSTHDQFKEVVELEKQLGGRLLEEPTTLNFKANSGNLRLSIHAIPDVLWTNKLLNTFQEIPFWHVWPGCQ-RLLHCTFALERASLSSTEFSCKLCVQQ--LEGEGQVLQLRTTLLNAPSATDDSPTEA-----ASAGSALVGP--QAFKLPYSIRQKLCSSLDSPNPRGNDWRLLAHRLGINRYGNYFEMRGSPTGVVLDLWEAQHEEDGDLDSLASVLEEMGRRE 901
BLAST of Netrin receptor UNC5B vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010609.1 (pep scaffold:Pmarinus_7.0:GL476332:154004:216612:1 gene:ENSPMAG00000009605.1 transcript:ENSPMAT00000010609.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 208.764 bits (530), Expect = 8.850e-56 Identity = 125/416 (30.05%), Postives = 210/416 (50.48%), Query Frame = 2
Query: 1799 WGTISTIGGRLCLPQSGITLTIAPGSFINSSSSEMYLAVSRNDPNPPILSDNETLLTPIVLFGPKDVPILKPCVLSVPHSADLRQGNWVIRLLSCVLPDQNDELKEPLCQPIWKNIATIGCETDQTP-IYTHLDPYAAFIMLDQPQKICLVGQSYPGGKATKRLRLAAFGRPLSTSSYLPNYNIRIYVFSDTKEAFESVSTIETKLGSTLLDITYQIIFSDSMGNLFFCIEEL-STGWKSQLTTKYQEIPFQDIWSGSQSETLHCAFTFDNIDPSQQSLTCRITAYQSGFYNQKQVITIKQDKLDRSNHKRDLIQHEKVLLYSESNNTYLDPLMTVFRISNATRKKLCFLLDNVTPRGNDWKQLCRQLSLN-GYLNYFMSKVSPTDALVTLWESRNRNENALIDLIISLKAIGRTD 3037
+GT +GGRL +P SG++L + PG+ + +MYL V R++ P+L ++TLL+P+V GP VP+L P +LS+ H A+L +W + LK L W+ + +G E + P + L+ A ++ + P ++G++ G A KRLRLAAF + S Y++R+Y +D E+ V +E +LG LL+ + F + GNL I + W ++L +QEIPF +W G Q LHC F + S +C++ Q + QV+ ++ L+ + D + + + + P F++ + R+KLC LD+ PRGNDW+ L +L +N + YF ++ SPT ++ LWE+++ + L L L+ +GR +
Sbjct: 578 YGTFGCMGGRLVIPNSGLSLLVPPGAIPSGQFYQMYLTVHRDEDKRPVLEGSQTLLSPVVSCGPPSVPLLSPVILSLRHCAELNSEDWAL------------GLKRQLDSGHWEEVLRLGEEPARPPSCHWQLEERACHVLTETPGTYAVLGEAL-GPAAVKRLRLAAFAPSVCPSL---EYSLRLYCLNDDAESLAEVVELEKQLGGRLLEEPTTLSFKANSGNLRLSIHAIPDVLWTNKLLNTFQEIPFWHVWPGCQ-RLLHCTFALERAGLSSTEFSCKLCVQQ--LEGEGQVLQLRTTLLNAPSATDDSPTEA-----ASAGSALVGP--QAFKLPYSIRQKLCSSLDSPNPRGNDWRLLAHRLGINSASMEYFETRGSPTGVVLDLWEAQHEEDGDLDSLASVLEEMGRKE 967 HSP 2 Score: 121.324 bits (303), Expect = 3.538e-28 Identity = 79/262 (30.15%), Postives = 123/262 (46.95%), Query Frame = 2
Query: 341 EGIPSFIKEPESVYYVYEKKPAKIVCIAEPVSHVNIICNKEVFSYMDLELSESNLRVRKMNKNNEDDLTNGHRWMFSLEITYNQVTEWFN--TFSCVCEAWNQIPSLRLAKKVHSRYGVIKEAYFKSNFKKVPQSKTVVKGQSLILTCVPPESKPKAQVQWMKNKKRL--FENNRIKIVEEHQLLIEDTLLTDSGNYSCIAISLEEKRYSPIAIVKIQESVTENPATQWSAWSACDGNCKKT---RTRNC------NSKGVC 1087
E +P F++EPE Y V KP + C A P + + CN E + E RV D+ T +++ QV E F + C C AW+ A SR ++ AY + NF++ P K V+ ++L C PP++ P+A+V+W+KN++ + + I +H L+I+ T L DS NY+C+A +L KR S A + + +QW+ WS C+ C + RTR+C N VC
Sbjct: 55 EPLPHFLQEPEDAYIV-RNKPVTMSCAASPATQIYFKCNGEWLHQKAHHIEE---RV--------DETTGRSVREVQTDVSRQQVEELFGLEDYWCQCVAWSA------AGTSKSRKAYVRIAYLRKNFEQEPLGKDVLLDHEVLLHCRPPDAIPQAEVEWLKNEEIIDPVIDQNFYITVDHNLIIKQTRLADSANYTCVAKNLVAKRRSSTATITV---YVNGGWSQWTEWSPCNSKCGRGTQKRTRSCSNPTPLNGGAVC 295
BLAST of Netrin receptor UNC5B vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003861.1 (pep scaffold:Pmarinus_7.0:GL476449:2630:55902:-1 gene:ENSPMAG00000003466.1 transcript:ENSPMAT00000003861.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 154.066 bits (388), Expect = 1.382e-38 Identity = 90/306 (29.41%), Postives = 152/306 (49.67%), Query Frame = 2
Query: 1781 DISTLAWGTISTIGGRLCLPQSGITLTIAPGSFINSSSSEMYLAVSRNDPNPPILSDNETLLTPIVLFGPKDVPILKPCVLSVPHSADLRQGNWVIRLLSCVLPDQNDELKEPLCQPIWKNIATIGCETDQTP-IYTHLDPYAAFIMLDQPQKICLVGQSYPGGKATKRLRLAAFGRPLSTSSYLPNYNIRIYVFSDTKEAFESVSTIETKLGSTLLDITYQIIFSDSMGNLFFCIEEL-STGWKSQLTTKYQEIPFQDIWSGSQSETLHCAFTFDNIDPSQQSLTCRITAYQSGFYNQKQVITIK 2692
D T + T +GGRL +P SG+ L + PG+ + +MYL V R + + P+L ++TLL+P+V GP +P+L P +LS+ H A+L +W + LK L W+ + +G E + P + L+ A ++ + P ++G++ G A KRLRLAAF + S Y++R+Y +D E+ V +E +LG ++ + F + G+L + + T W + + +K QEIPF +W G Q LHC F + S +C++ Q + QV+ ++
Sbjct: 522 DKGTSVYATFGCLGGRLLIPSSGVGLLVPPGAIPHGHFYQMYLTVHRGEDSGPVLDGSQTLLSPVVSCGPPSIPLLSPVILSLRHCAELSPEDWAL------------SLKRQLSSGHWEEVLRLGEEPARPPSCHWQLEERACHVLTETPGTYAVLGEAL-GPAAVKRLRLAAFAPSVCPSL---EYSLRLYCLNDDTESLAEVVELEKRLGGHMVGEPSTLHFKANSGHLQLSMHAVPDTLWTNNVHSKLQEIPFWHVWPGCQ-RLLHCTFALERAGLSSTEFSCKLCVQQ--LEGEGQVLQLR 808 HSP 2 Score: 112.079 bits (279), Expect = 1.977e-25 Identity = 74/259 (28.57%), Postives = 120/259 (46.33%), Query Frame = 2
Query: 341 EGIPSFIKEPESVYYVYEKKPAKIVCIAEPVSHVNIICNKEVFSYMDLELSE-SNLRVRKMNKNNEDDLTNGHRWMFSLEITYNQVTEWFNTFSCVCEAWNQIPSLRLAKKVHSRYGVIKEAYFKSNFKKVPQSKTVVKGQSLILTCVPPESKPKAQVQWMKNKKRL--FENNRIKIVEEHQLLIEDTLLTDSGNYSCIAISLEEKRYSPIAIVKIQESVTENPATQWSAWSACDGNCKKTRTRNCNSKGVCKEIDSCT 1108
E +P F++E E Y V KP + C A P + + CN E S + + ++ + + + D++ +E+ Y W C C AW+ A SR ++ AY NF+ PQ K +GQ + L C PP++ P A+V+W+KN+ + E++ I +H L+I+ L+DS NY+C+A +L KR S A V + E + W+ W+ C+ C +G K I +CT
Sbjct: 34 EPLPHFLQELEDAYIV-RNKPVTMSCAASPATQIYFKCNAEWVSQQAHHVQQRTDQGTGRSVREVQTDVSRQQ-----VEVYYGPEPYW-----CQCVAWSA------AGTSKSRKAYVRIAYLHKNFEMEPQGKEEPQGQKIQLHCRPPDAVPPAEVEWLKNEMLIDPEEDSNFHITADHNLIIKQARLSDSANYTCVAKNLVAKRRSSTATVTV---YVEGGWSLWNEWAPCNSKC---------GRGTQKRIRTCT 263
BLAST of Netrin receptor UNC5B vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010567.1 (pep scaffold:Pmarinus_7.0:GL479154:561817:685780:1 gene:ENSPMAG00000009565.1 transcript:ENSPMAT00000010567.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 58.151 bits (139), Expect = 1.137e-8 Identity = 55/222 (24.77%), Postives = 94/222 (42.34%), Query Frame = 2
Query: 335 KLEGIPSFIKEPESVYYVYEKKPAKIVCIAE--PVSHVNIICNKEVFSYMDLELSESNLRVRKMNKNNEDDLTNGHRWMFSLEITYNQVTEWFNTFSCVCEAWNQIPSLRLAKKVHSRYGVIKEAYFKSNFKKVPQSKTVVKGQSLILTCVPPESKPKAQVQWMKNKKRLFENNRIKIVEEHQLLIEDTLLTDSGNYSCIAISLEEKRYSPIAIVKIQESVT 994
+ E P I E S V +PA + C AE P V Y D E E++ R +++ L G +F L I + + T+ + S VC A N + + SR ++ A + N++ P + V + ++ C PP P+ V W +N L + + + +L+I +T D+G Y C+ ++ +R S A + + E T
Sbjct: 24 RQEDAPPRIAEHPSDLIVSRGEPATLNCKAEGRPAPTVEW--------YKDGERVETD---RDDPRSHRMLLPTGS--LFFLRIVHGRRTK-TDEGSYVCVARNYL------GEAVSRNASLEVANIRRNYRSSPSAVKVAAREPAVMECRPPRGHPEPTVSWKRNGVALTDKDERVTIRGGKLMISNTQKADAGMYVCVGTNMVGERDSEPAELAVFERPT 225
BLAST of Netrin receptor UNC5B vs. Ensembl Sea Lamprey
Match: tjp1a (tight junction protein 1a [Source:ZFIN;Acc:ZDB-GENE-031001-2]) HSP 1 Score: 54.6842 bits (130), Expect = 1.172e-7 Identity = 42/132 (31.82%), Postives = 64/132 (48.48%), Query Frame = 2
Query: 1697 RPPSALYHELSLDRESICNSPPFVSENIDISTLAW--GTISTIGGRLCLPQSGITLTIAPGSFINSSSSEMYLAVSRNDPNPPILSDN--ETLLTPIVLFGPKDVPILKPCVLSVPHSADLRQGNWVIRLLS 2080
RP S L LS ++I SP +SE S +A G + GG L ++G+++ + G+ E+Y V +++ P L ETLL+P+V+ GP + LKP L +PH A + W L S
Sbjct: 1604 RPKSHL-DGLSATPKAIPVSPSALSEEEGHSVVATARGVFDSNGGVLSSVETGVSVVVPRGAIPEGLEQEIYFKVCQDNSIIPALDKEKGETLLSPLVMCGPHGLRFLKPVELRLPHCAAMNPDGWSFALKS 1734
BLAST of Netrin receptor UNC5B vs. Ensembl Nematostella
Match: EDO46601 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RPN0]) HSP 1 Score: 96.2857 bits (238), Expect = 4.132e-20 Identity = 104/459 (22.66%), Postives = 187/459 (40.74%), Query Frame = 2
Query: 1760 PFVSENIDISTLAWGTISTIGGRLCLPQSGITLTIAPGSFINSSSSEMYLAVSRNDPNPPILSDNETLLTPIVLFGPKDVPILKPCVLSVPHSADLRQGNWVIRLLSCVLPDQNDELK--EPLCQPIWKNIATIGCETDQTPIYTHLDPYAAFIMLDQPQKICLVGQSYPGGKATKRLRLAAFGRPLSTSSYLPNYNIRIYVFSDTKEAFESVSTIETKLGSTLLDIT--YQIIFSDSMGNLFFCIEELSTGWKSQLTTKYQEIPFQDIWSGSQSETLHCAFTFDNIDPSQQSLT---CRITAYQSGFYNQKQVITI-------KQDKLDRSNHKRDLIQHEKVLLYSESNNTYLDPLM---TVFRISNATRKKLCFLLDNVTPRGN----DWKQLCRQLS--LNGYLNYFMSKV---SPTDALVTLWESRNRNENALIDLIISLKAIGRTDCSTLLES 3058
P + E D AWG I GG+L +P +GI+L + P + +Y+A+ + P L + LL+P V+ GP+ + +P L +PH+A L+ G +P + + E W+ + ++ + + PI ++LD + +ML Q+ G ++++ F L + +++Y+ TK A E +++G D + ++ + + C+ E+ T WK +T Q +PF +WS S + + F F I P Q +LT C Q G + ++ ++ + S K+ + S+ + M +I R KLC L+ P N WK L ++ ++ Y + P AL+ WE+ + L L ++ IGR D + L+ES
Sbjct: 587 PSLPERADERLCAWGRIDHNGGQLVIPNTGISLYVPPSALPQGQEEVIYIAMMKRSAKYPQLRPGQALLSPAVVCGPEGLQFNEPVFLKLPHNAALKNGE---------IPHLEGKTRSGESTDATTWRTLESLDGDPESRPI-SYLDENSVEMMLTH-----FSDQTVVGEPEYLKIKVVPF---LQCDGAQFDCRVQVYLIPRTKAALEEAILDASRVGLIQADTGKLFSLMNTSRDVRVKACLHEVDTKWKP-VTPVQQALPFSQVWS-SVEDMPNVTFGFAPI-PDQPNLTTFRCNFEIQQYGETDLARIFVTYCIKDHEEEGAVGSSASTPTSSPQRKLERWDSSSTLGIGSEMQGPNENKIPRDIRIKLCIKLE---PADNLMIGSWKDLAGKIPGITTDHIRYLEGRKVGDGPVGALIDYWETSLSEKIPLHQLAQLMEDIGRRDAAELVES 1021
BLAST of Netrin receptor UNC5B vs. Ensembl Nematostella
Match: EDO41849 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S398]) HSP 1 Score: 82.4185 bits (202), Expect = 6.745e-16 Identity = 72/312 (23.08%), Postives = 130/312 (41.67%), Query Frame = 2
Query: 1766 VSENIDISTLAWGTISTIGGRLCLPQSGITLTIAPGSFINSSSSEMYLAVSR-NDPNPPILSDN-ETLLTPIVLFGPKDVPILKPCVLSVPHSADLRQGNWVIRLLSCVLPDQNDELKEPLCQPI-WKNIATIGCETDQTPIYTHLDPYAAFIMLDQPQKICLVGQSYPGGKATKRLRLAAFGRPLSTSSYLPNYNIRIYVFSDTKEAFESVSTIETKLGSTLLDITYQIIFSDSMGNLFFCIEELSTGWKSQLTTKYQEIPFQDIWSGS-QSETLHCAFTFDNIDPSQQSLTCRITAYQSGFYNQKQVITI 2689
+ ++ + A G + GG L +SG+++ I G+ E+Y V + N+ PP+ ++ ETLL+P+V+ GP LK L +PH A + W L S P P W+N++ G E +DP + +++D L G++ ATKR+ + F +P T+S + + + + A V ET G I ++ + +++ GW S+ K + I FQD W Q+ T++ F + + C + +Q G + ++ +
Sbjct: 803 LEDDTQVVATARGIFTHEGGVLSSEESGVSIFIPEGAIPKGVEQEIYFKVCKENNIMPPLDTEKGETLLSPLVMCGPHGTKFLKSVELRLPHCAAMTPDGWSFALKSS---------DTPTGMPTQWRNVSLPGQEHKDK---CQVDPNSVSVLVDHFSSFSLAGEAR--SNATKRMVASVFAQPPMTNS---EWLFHVVLADNMDSARREVQQAETACGRLQFSPFVPIDVHGDAKDVRVQLRDIADGWISRSACK-KYIEFQDTWEAYLQNPTVN--FVVHDRARGRVPNVCEVEVWQEGHEREAVILDV 1094
BLAST of Netrin receptor UNC5B vs. Ensembl Nematostella
Match: EDO35240 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SM31]) HSP 1 Score: 56.6102 bits (135), Expect = 5.491e-9 Identity = 30/93 (32.26%), Postives = 46/93 (49.46%), Query Frame = 2
Query: 707 FKSNFKKVPQSKTVVKGQSLILTCVPPESKPKAQVQWMKNKKRLFENN-RIKIVEEHQLLIEDTLLTDSGNYSCIAISLEEKRYSPIAIVKIQ 982
+S F+ P+ ++ G IL C PP+ +P V W+KN K + RI+ V L+I D G Y C+A + +R S +A V I+
Sbjct: 1 LRSKFRAEPKDLSITIGNRAILKCNPPKGRPAPTVTWLKNTKAYVPDGVRIQKVSPGNLVISIAQKADMGTYQCVAANAVGRRKSRVATVTIK 93
BLAST of Netrin receptor UNC5B vs. Ensembl Nematostella
Match: EDO45713 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRZ5]) HSP 1 Score: 57.7658 bits (138), Expect = 2.302e-8 Identity = 55/251 (21.91%), Postives = 105/251 (41.83%), Query Frame = 2
Query: 1808 ISTIGGRLCLPQSGITLTIAPGSFINSSSSEMY----LAVSRNDPNPPILSDNETLLTPIVLFGPKDVPILKPCVLSVPHSADLRQGN-WVIRLLSC----VLPDQNDELKEPLCQP--IWKNIATIGCETDQTPIYTHLDPYAAFIMLDQPQKICLVGQSYPGGKATKRLRLAAFGRPLSTSSYLPN---YNIRIYVFSDTKEAFESVSTIETKLGSTLLDITYQI-IFSDSMGNLFFCIEELSTGWKSQ 2515
++ G L P +G+ L + + +E+Y + V + P+ P L+++E LL+P + P + +P + +PH+ADL N W +R+L+C P+ D+L C + N+ +G A+ ++ P + L A KR+ A F + ++P ++ Y+ D + + + V E + G + + + +D G + I L+ GWK Q
Sbjct: 390 VTGEGNVLWFPTAGVKLHLPHEFYGEGVDNEVYGKIKIGVHHDRPSLPTLNEHEVLLSPAIRIRPDGAELQEPITIEIPHTADLGTDNQWSLRVLTCYDTQAGPEWTDDLMSVKCGELSVSFNVTKLG---------------VAYAVVGSPVNLRL---------AKKRMVCAVFA-----AQHIPGNEPVDVVCYLLDDCESSLKRVR--ENEHGQEMYGCLKKCHLHTDPNGEIRLQIANLTDGWKVQ 609
BLAST of Netrin receptor UNC5B vs. Ensembl Nematostella
Match: EDO34058 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SQE0]) HSP 1 Score: 49.2914 bits (116), Expect = 1.518e-6 Identity = 20/64 (31.25%), Postives = 36/64 (56.25%), Query Frame = 2
Query: 743 TVVKGQSLILTCVPPESKPKAQVQWMKNKKRLFENNRIKIVEEHQLLIEDTLLTDSGNYSCIAI 934
T++ G++ +L C S P +W+K+ K L R+ ++ L+IE T+ +D NY+C A+
Sbjct: 9 TLIAGETAVLQCTAAGS-PTPYFRWLKSGKSLTMGGRMSVIAGGSLMIESTMASDEANYTCQAV 71
BLAST of Netrin receptor UNC5B vs. Ensembl Medaka
Match: unc5db (netrin receptor UNC5D [Source:NCBI gene;Acc:101173475]) HSP 1 Score: 261.922 bits (668), Expect = 6.251e-73 Identity = 226/989 (22.85%), Postives = 410/989 (41.46%), Query Frame = 2
Query: 347 IPSFIKEPESVYYVYEKKPAKIVCIAEPVSHVNIICNKEVF---SYMDLELSE--SNLRVRKMNKNNEDDLTNGHRWMFSLEITYNQVTEWFN--TFSCVCEAWNQIPSLRLAKKVHSRYGVIKEAYFKSNFKKVPQSKTVVKGQSLILTCVPPESKPKAQVQWMKNKKRL--FENNRIKIVEEHQLLIEDTLLTDSGNYSCIAISLEEKRYSPIAIVKI-------------------------QESVTENPA----------------------------TQWSAWSACDGNCKKTRTRNCNS----------KGVCKEIDSCTKKECEYNRAVAPFVKNPNKNGVSTSSLQDARDIAMYVGLFVAVTILVMVITIIFCLIRRKALLPLRSTMRYPLNINGNGVAYDVKNSLIKNSNTISTKNPYIMDTSL-ANLTQQRSYLSQSPPNLPPPTCLSEISSTNAYSTGIDFSYNSTGSGKFSQPLIXXXXXXXXXXXXXXXXXXXXDHKPDPLTVSGTPINSRPPSALYHELSLD---------RESICNSPPFVSENIDISTLAWGTISTIGGRLCLPQSGITLTIAPGSFINSSSSEMYLAVSRNDPNPPILSDNETLLTPIVLFGPKDVPILKPCVLSVPHSADLRQGNWVIRLLSCVLPDQNDELKEPLCQPIWKNIATIGCETDQTPIYTHLDPYAAFIMLDQPQKICLVGQSYPGGKATKRLRLAAFGRPLSTSSYLPNYNIRIYVFSDTKEAFESVSTIETKLGSTLLDITYQIIFSDSMGNLFFCIEELSTG-WKSQLTTKYQEIPFQDIWSGSQSETLHCAFTFDNIDPSQQSLTCRITAYQSGFYNQKQVITIKQDKLDRSNHKRDLIQHEKVLLYSESNNTYLDPLMTVFRISNATRKKLCFLLDNVTPRGNDWKQLCRQLSLNGYLNYFMSKVSPTDALVTLWESRNRNENALIDLIISLKAIGRT-DCSTLLESD 3061
+P FI+EPE Y V + P K+ C A P + CN E +M E + + L+VR++ N I+ QV ++ + C+C AW+ + + + SR ++ AY + NF++ PQ K V + ++L C PPE P +V+W+KN++ + ++ I + L+I + L+DSGNY+C+A ++ KR S A V + + NPA +WS W+ C+ C + RTR C+S +G + ++CT C NR + ++ V S++ + D+A+Y+ L + + ++ ++ +L +S Y +++ + S N T S NP ++++S+ ++LT R+Y + P C E + + D + S S + DH P V P +L + ++++ S P + T G GGRL +P +G++L + G+ S E+Y+ +++ + + L E LL P V +GP ++ + P ++VPH A + + NW N +L+ W+ + + + + T + +D ++LDQP LVG+ A KRL+L FG ++S+ NY +R+Y DT F+ V E G LL+ + F + NL I+++ W + T QE F +W +Q + +HC F + P+ L+C+I+ Q +Q++ + + + S++ F+I ++ R+++C D +G DW+ L ++L L+ L YF + SP+ +++LWE + + + L L +L+ IG+ CS+ + D
Sbjct: 40 LPHFIQEPEDAYIV-KSNPTKLRCRATPALQIFFKCNGEWVHQNEHMSHEYKDLITGLKVREVMIN----------------ISRQQVEDFHGPEDYWCLCVAWSHLGTSK------SRKATVRIAYLRKNFEQDPQGKEVPINRMIVLHCRPPEGVPAVEVEWLKNEELVSSMTDDNIDSRADQNLIINEARLSDSGNYTCLASNIVAKRRSATATVIVFVNGGWSLWTEWSPCNVPCGWGVQKRSRTCTNPAPLNGGAFCEGMSVQKIPCNALCPVDGGWDEWSEWTLCNSLCGRHRTRECSSPAPRHRGKMCEGNSEATENCTDGLCTQNRNL--------RHDVKPQSMEGSNDVALYLCLGAGIIAVAFLVVVV--------MLYRKSHSEYGVDVIDSSALTRGCQSF--NFKTTSQGNPLLLNSSMRSDLTVGRTYST--------PICFHESADKELFDPLPDIAVKVQSSFMISLGV--------------------ADHATFPDKV--------PAETYQRDLGCEYCSTMERRKKDTLMFSRPIAVDKEQPRTS--GVFGHQGGRLAVPSTGVSLLVPHGAVAEYMSCEVYMVINQGESSIETLEGCEILLGPEVTYGPSNLDLFCPAAVTVPHCAVVDKENW------------NIQLRRKTQDSKWEEVMLV--DEESTSCFCLMDSTCCHLLLDQPGSYALVGEPL-NQAAMKRLKLGVFGGLEASST---NYCLRVYCVDDTPHGFQRVVAAERTRGGQLLEEPKMLPFQANTFNLQVSIQDVPQFLWSIKPFTTCQEFSFSQVWCSNQ-QPMHCTFALERFSPATAQLSCKISVRQ--VKGHEQILQVYTAVAEGEKESPPFFMQTDCSVTSQTGP-------KAFKIPSSIRERICATFDTANAKGKDWQLLAQKLHLDRNLGYFAKQHSPSAVILSLWEVCHPDADDLDSLANALEEIGKIHSCSSPEDQD 921
BLAST of Netrin receptor UNC5B vs. Ensembl Medaka
Match: si:ch73-72b7.1 (netrin receptor UNC5C [Source:NCBI gene;Acc:101174433]) HSP 1 Score: 250.751 bits (639), Expect = 5.105e-69 Identity = 149/422 (35.31%), Postives = 226/422 (53.55%), Query Frame = 2
Query: 1781 DISTLAWGTISTIGGRLCLPQSGITLTIAPGSFINSSSSEMYLAVSRNDPNPPILSDNETLLTPIVLFGPKDVPILKPCVLSVPHSADLRQGNWVIRLLSCVLPDQNDELKEPLCQPIWKNIATIGCETDQTPIYTHLDPYAAFIMLDQPQKICLVGQSYPGGKATKRLRLAAFGRPLSTSSYLPNYNIRIYVFSDTKEAFESVSTIETKLGSTLLDITYQIIFSDSMGNLFFCIEEL-STGWKSQLTTKYQEIPFQDIWSGSQSETLHCAFTFDNIDPSQQSLTCRITAYQSGFYNQKQVITIKQDKLDRSNHKRDLIQHEKVLLYSESNNTYLDPLMTVFRISNATRKKLCFLLDNVTPRGNDWKQLCRQLSLNGYLNYFMSKVSPTDALVTLWESRNRNENALIDLIISLKAIGRTDCS 3043
D S A G+ ++ GG L +P SG++L + G+ EM + V R D P + D +T+L+P+V GP + +P +L++ H AD Q +W+I +LK L W+++ +G E TP Y +D A I+ + CLVGQS G A KRL+LA FG P+S ++ +Y+IR+Y DT++A + V +ET++G LLD + F DS NL I ++ WKS+L KYQEIPF +WSGSQ +LHC FT + + P+ L+C++ Q + Q+ + SN + +Q L ++N FRI + R+KLC LD RGNDW+ L +L+L+ YLNYF +K SPT ++ LWE+++ + L +L L+ +GR D S
Sbjct: 552 DPSCTAHGSFNSQGGHLIVPNSGVSLLVPAGAIPQGRVYEMCVTVHRKDSLRPPVEDIQTVLSPVVSCGPAGALLTRPVILTIHHCADNVQEDWLI------------QLKNRLSMGEWEDVVVVGEENFTTPCYVQMDSEACHILTETLGTYCLVGQSI-GKAAAKRLKLAVFG-PVSCTTL--DYHIRVYCLDDTQDALKEVLQMETQMGGKLLDEPKTLNFKDSTHNLRLSIHDVPHMQWKSKLIAKYQEIPFHQVWSGSQ-RSLHCTFTLERLTPATMELSCKLCVRQ--VEGEGQIFQL-------SNTLEEELQCIDTSLMDPASNITTLTGPNAFRIPLSIRQKLCGSLDAPQTRGNDWRMLAHKLNLDRYLNYFATKSSPTGVILDLWEAQHFPDGDLNELAAVLEEMGRHDSS 947 HSP 2 Score: 135.191 bits (339), Expect = 8.316e-32 Identity = 110/438 (25.11%), Postives = 180/438 (41.10%), Query Frame = 2
Query: 293 EIEDENDFVKLNE-------SKLEGIPSFIKEPESVYYVYEKKPAKIVCIAEPVSHVNIICNKEVFSYMDLELSE-----SNLRVRKMNKNNEDDLTNGHRWMFSLEITYNQVTEWFN--TFSCVCEAWNQIPSLRLAKKVHSRYGVIKEAYFKSNFKKVPQSKTVVKGQSLILTCVPPESKPKAQVQWMKNKKRL--FENNRIKIVEEHQLLIEDTLLTDSGNYSCIAISLEEKRYSPIAIVKI-------------------------------------------QESVTENPAT----------QWSAWSACDGNCKKTRTRNCNS----------KGVCKEIDSCTKKECEYNRAVAPFVKNPNKNGVSTSSLQDARDIAMYVGLFVAVTILVMVITIIFCLIRRKALLPLRSTMRYPLNINGNGVAYDVKNS 1369
++ D++DF+ L+E E +P F+ EPE Y V + KP + C A P + + CN E D + E S L VR+ S+EIT QV E F + C C AW+ A SR ++ AY K +F++ P K V Q ++L C PPE P A+V+W+KN++ + E+ I +H L+I+ L+D+ NY+C+A ++ KR S A V + +++ + P T +WS WSAC C + R R CN+ +G+ + +CT C + K + S D+A+YVG+ +AV + +++ I+ + RK S + +NG + ++K +
Sbjct: 39 QVRDDDDFLSLSELPETFPSDPPEPLPHFLFEPEEGYIV-KNKPVNLYCKATPATQIYFKCNSEWVHQKDHTVEERVDENSGLVVREA----------------SIEITRQQVEELFGPEDYWCQCVAWSS------AGTTKSRKAHVRIAYLKKSFEQEPLGKEVSLEQEVLLQCRPPEGIPAAEVEWLKNEEVIDPAEDRNFYITIDHNLIIKQARLSDTANYTCVAKNIVAKRRSTTATVIVYVNGGWSTWTEWSPCNSRCGRGFQKRTRSCTNPTPLNGGLPCDGQAIQKLPCTTLCTVDGVWTEWSKWSACGTECTQWRRRECNNPAPKNGGKDCEGLVLQSQNCTDGLCMQSSLFQKSNVPKEKTDLGMPSAPSTDDVALYVGIVIAVIMCLVISVIVALFVYRKTHRDFDSDIIDTSALNGGFQSVNIKTA 453
BLAST of Netrin receptor UNC5B vs. Ensembl Medaka
Match: si:ch73-72b7.1 (netrin receptor UNC5C [Source:NCBI gene;Acc:101174433]) HSP 1 Score: 249.98 bits (637), Expect = 5.346e-69 Identity = 149/422 (35.31%), Postives = 226/422 (53.55%), Query Frame = 2
Query: 1781 DISTLAWGTISTIGGRLCLPQSGITLTIAPGSFINSSSSEMYLAVSRNDPNPPILSDNETLLTPIVLFGPKDVPILKPCVLSVPHSADLRQGNWVIRLLSCVLPDQNDELKEPLCQPIWKNIATIGCETDQTPIYTHLDPYAAFIMLDQPQKICLVGQSYPGGKATKRLRLAAFGRPLSTSSYLPNYNIRIYVFSDTKEAFESVSTIETKLGSTLLDITYQIIFSDSMGNLFFCIEEL-STGWKSQLTTKYQEIPFQDIWSGSQSETLHCAFTFDNIDPSQQSLTCRITAYQSGFYNQKQVITIKQDKLDRSNHKRDLIQHEKVLLYSESNNTYLDPLMTVFRISNATRKKLCFLLDNVTPRGNDWKQLCRQLSLNGYLNYFMSKVSPTDALVTLWESRNRNENALIDLIISLKAIGRTDCS 3043
D S A G+ ++ GG L +P SG++L + G+ EM + V R D P + D +T+L+P+V GP + +P +L++ H AD Q +W+I +LK L W+++ +G E TP Y +D A I+ + CLVGQS G A KRL+LA FG P+S ++ +Y+IR+Y DT++A + V +ET++G LLD + F DS NL I ++ WKS+L KYQEIPF +WSGSQ +LHC FT + + P+ L+C++ Q + Q+ + SN + +Q L ++N FRI + R+KLC LD RGNDW+ L +L+L+ YLNYF +K SPT ++ LWE+++ + L +L L+ +GR D S
Sbjct: 518 DPSCTAHGSFNSQGGHLIVPNSGVSLLVPAGAIPQGRVYEMCVTVHRKDSLRPPVEDIQTVLSPVVSCGPAGALLTRPVILTIHHCADNVQEDWLI------------QLKNRLSMGEWEDVVVVGEENFTTPCYVQMDSEACHILTETLGTYCLVGQSI-GKAAAKRLKLAVFG-PVSCTTL--DYHIRVYCLDDTQDALKEVLQMETQMGGKLLDEPKTLNFKDSTHNLRLSIHDVPHMQWKSKLIAKYQEIPFHQVWSGSQ-RSLHCTFTLERLTPATMELSCKLCVRQ--VEGEGQIFQL-------SNTLEEELQCIDTSLMDPASNITTLTGPNAFRIPLSIRQKLCGSLDAPQTRGNDWRMLAHKLNLDRYLNYFATKSSPTGVILDLWEAQHFPDGDLNELAAVLEEMGRHDSS 913 HSP 2 Score: 131.724 bits (330), Expect = 1.107e-30 Identity = 110/421 (26.13%), Postives = 179/421 (42.52%), Query Frame = 2
Query: 296 IEDENDFVKLNE-------SKLEGIPSFIKEPESVYYVYEKKPAKIVCIAEPVSHVNIICNKEVFSYMDLELSE-----SNLRVRKMNKNNEDDLTNGHRWMFSLEITYNQVTEWFN--TFSCVCEAWNQIPSLRLAKKVHSRYGVIKEAYFKSNFKKVPQSKTVVKGQSLILTCVPPESKPKAQVQWMKNKKRL--FENNRIKIVEEHQLLIEDTLLTDSGNYSCIAISLEEKRYSPIAIVKIQESVTENPATQWSAWSACDGNCKK---TRTRNCNS--------------------------KGVCKE---IDSCTKKECEYNRAVA--PFVKNPNK-------------NGVSTSSLQDARDIAMYVGLFVAVTILVMVITIIFCLIRRKALLPLRSTMRYPLNINGNGVAYDVKNS 1369
+ D++DF+ L+E E +P F+ EPE Y V + KP + C A P + + CN E D + E S L VR+ S+EIT QV E F + C C AW+ A SR ++ AY K +F++ P K V Q ++L C PPE P A+V+W+KN++ + E+ I +H L+I+ L+D+ NY+C+A ++ KR S A V + + W+ WS C+ C + RTR+C + GV E +C + ++ R P KN K +G+ + D+A+YVG+ +AV + +++ I+ + RK S + +NG + ++K +
Sbjct: 25 LRDDDDFLSLSELPETFPSDPPEPLPHFLFEPEEGYIV-KNKPVNLYCKATPATQIYFKCNSEWVHQKDHTVEERVDENSGLVVREA----------------SIEITRQQVEELFGPEDYWCQCVAWSS------AGTTKSRKAHVRIAYLKKSFEQEPLGKEVSLEQEVLLQCRPPEGIPAAEVEWLKNEEVIDPAEDRNFYITIDHNLIIKQARLSDTANYTCVAKNIVAKRRSTTATVIV---YVNGGWSTWTEWSPCNSRCGRGFQKRTRSCTNPTPLNGGLPCDGQAIQKLPCTTLCTVDGVWTEWSKWSACGTECTQWRRRECNNPAPKNGGKDCEGLVLQSQNCTDGLCMQTAPSTDDVALYVGIVIAVIMCLVISVIVALFVYRKTHRDFDSDIIDTSALNGGFQSVNIKTA 419
BLAST of Netrin receptor UNC5B vs. Ensembl Medaka
Match: si:ch73-72b7.1 (netrin receptor UNC5C [Source:NCBI gene;Acc:101174433]) HSP 1 Score: 250.366 bits (638), Expect = 5.529e-69 Identity = 149/422 (35.31%), Postives = 226/422 (53.55%), Query Frame = 2
Query: 1781 DISTLAWGTISTIGGRLCLPQSGITLTIAPGSFINSSSSEMYLAVSRNDPNPPILSDNETLLTPIVLFGPKDVPILKPCVLSVPHSADLRQGNWVIRLLSCVLPDQNDELKEPLCQPIWKNIATIGCETDQTPIYTHLDPYAAFIMLDQPQKICLVGQSYPGGKATKRLRLAAFGRPLSTSSYLPNYNIRIYVFSDTKEAFESVSTIETKLGSTLLDITYQIIFSDSMGNLFFCIEEL-STGWKSQLTTKYQEIPFQDIWSGSQSETLHCAFTFDNIDPSQQSLTCRITAYQSGFYNQKQVITIKQDKLDRSNHKRDLIQHEKVLLYSESNNTYLDPLMTVFRISNATRKKLCFLLDNVTPRGNDWKQLCRQLSLNGYLNYFMSKVSPTDALVTLWESRNRNENALIDLIISLKAIGRTDCS 3043
D S A G+ ++ GG L +P SG++L + G+ EM + V R D P + D +T+L+P+V GP + +P +L++ H AD Q +W+I +LK L W+++ +G E TP Y +D A I+ + CLVGQS G A KRL+LA FG P+S ++ +Y+IR+Y DT++A + V +ET++G LLD + F DS NL I ++ WKS+L KYQEIPF +WSGSQ +LHC FT + + P+ L+C++ Q + Q+ + SN + +Q L ++N FRI + R+KLC LD RGNDW+ L +L+L+ YLNYF +K SPT ++ LWE+++ + L +L L+ +GR D S
Sbjct: 533 DPSCTAHGSFNSQGGHLIVPNSGVSLLVPAGAIPQGRVYEMCVTVHRKDSLRPPVEDIQTVLSPVVSCGPAGALLTRPVILTIHHCADNVQEDWLI------------QLKNRLSMGEWEDVVVVGEENFTTPCYVQMDSEACHILTETLGTYCLVGQSI-GKAAAKRLKLAVFG-PVSCTTL--DYHIRVYCLDDTQDALKEVLQMETQMGGKLLDEPKTLNFKDSTHNLRLSIHDVPHMQWKSKLIAKYQEIPFHQVWSGSQ-RSLHCTFTLERLTPATMELSCKLCVRQ--VEGEGQIFQL-------SNTLEEELQCIDTSLMDPASNITTLTGPNAFRIPLSIRQKLCGSLDAPQTRGNDWRMLAHKLNLDRYLNYFATKSSPTGVILDLWEAQHFPDGDLNELAAVLEEMGRHDSS 928 HSP 2 Score: 132.494 bits (332), Expect = 5.413e-31 Identity = 110/422 (26.07%), Postives = 180/422 (42.65%), Query Frame = 2
Query: 293 EIEDENDFVKLNE-------SKLEGIPSFIKEPESVYYVYEKKPAKIVCIAEPVSHVNIICNKEVFSYMDLELSE-----SNLRVRKMNKNNEDDLTNGHRWMFSLEITYNQVTEWFN--TFSCVCEAWNQIPSLRLAKKVHSRYGVIKEAYFKSNFKKVPQSKTVVKGQSLILTCVPPESKPKAQVQWMKNKKRL--FENNRIKIVEEHQLLIEDTLLTDSGNYSCIAISLEEKRYSPIAIVKIQESVTENPATQWSAWSACDGNCKK---TRTRNCNS--------------------------KGVCKE---IDSCTKKECEYNRAVA--PFVKNPNK-------------NGVSTSSLQDARDIAMYVGLFVAVTILVMVITIIFCLIRRKALLPLRSTMRYPLNINGNGVAYDVKNS 1369
++ D++DF+ L+E E +P F+ EPE Y V + KP + C A P + + CN E D + E S L VR+ S+EIT QV E F + C C AW+ A SR ++ AY K +F++ P K V Q ++L C PPE P A+V+W+KN++ + E+ I +H L+I+ L+D+ NY+C+A ++ KR S A V + + W+ WS C+ C + RTR+C + GV E +C + ++ R P KN K +G+ + D+A+YVG+ +AV + +++ I+ + RK S + +NG + ++K +
Sbjct: 39 QVRDDDDFLSLSELPETFPSDPPEPLPHFLFEPEEGYIV-KNKPVNLYCKATPATQIYFKCNSEWVHQKDHTVEERVDENSGLVVREA----------------SIEITRQQVEELFGPEDYWCQCVAWSS------AGTTKSRKAHVRIAYLKKSFEQEPLGKEVSLEQEVLLQCRPPEGIPAAEVEWLKNEEVIDPAEDRNFYITIDHNLIIKQARLSDTANYTCVAKNIVAKRRSTTATVIV---YVNGGWSTWTEWSPCNSRCGRGFQKRTRSCTNPTPLNGGLPCDGQAIQKLPCTTLCTVDGVWTEWSKWSACGTECTQWRRRECNNPAPKNGGKDCEGLVLQSQNCTDGLCMQTAPSTDDVALYVGIVIAVIMCLVISVIVALFVYRKTHRDFDSDIIDTSALNGGFQSVNIKTA 434
BLAST of Netrin receptor UNC5B vs. Ensembl Medaka
Match: unc5db (netrin receptor UNC5D [Source:NCBI gene;Acc:101173475]) HSP 1 Score: 248.054 bits (632), Expect = 1.897e-68 Identity = 218/971 (22.45%), Postives = 394/971 (40.58%), Query Frame = 2
Query: 368 PESVYYVYEKKPAKIVCIAEPVSHVNIICNKEVF---SYMDLELSE--SNLRVRKMNKNNEDDLTNGHRWMFSLEITYNQVTEWFN--TFSCVCEAWNQIPSLRLAKKVHSRYGVIKEAYFKSNFKKVPQSKTVVKGQSLILTCVPPESKPKAQVQWMKNKKRL--FENNRIKIVEEHQLLIEDTLLTDSGNYSCIAISLEEKRYSPIAIVKI-------------------------QESVTENPA----------------------------TQWSAWSACDGNCKKTRTRNCNSKGVCKEIDSCTKKECEYNRAVAPFVKNPNKNGVSTSSLQDARDIAMYVGLFVAVTILVMVITIIFCLIRRKALLPLRSTMRYPLNINGNGVAYDVKNSLIKNSNTISTKNPYIMDTSL-ANLTQQRSYLSQSPPNLPPPTCLSEISSTNAYSTGIDFSYNSTGSGKFSQPLIXXXXXXXXXXXXXXXXXXXXDHKPDPLTVSGTPINSRPPSALYHELSLD---------RESICNSPPFVSENIDISTLAWGTISTIGGRLCLPQSGITLTIAPGSFINSSSSEMYLAVSRNDPNPPILSDNETLLTPIVLFGPKDVPILKPCVLSVPHSADLRQGNWVIRLLSCVLPDQNDELKEPLCQPIWKNIATIGCETDQTPIYTHLDPYAAFIMLDQPQKICLVGQSYPGGKATKRLRLAAFGRPLSTSSYLPNYNIRIYVFSDTKEAFESVSTIETKLGSTLLDITYQIIFSDSMGNLFFCIEELSTG-WKSQLTTKYQEIPFQDIWSGSQSETLHCAFTFDNIDPSQQSLTCRITAYQSGFYNQKQVITIKQDKLDRSNHKRDLIQHEKVLLYSESNNTYLDPLMTVFRISNATRKKLCFLLDNVTPRGNDWKQLCRQLSLNGYLNYFMSKVSPTDALVTLWESRNRNENALIDLIISLKAIGRTDCSTLLESD 3061
PE Y V + P K+ C A P + CN E +M E + + L+VR++ N I+ QV ++ + C+C AW+ + + + SR ++ AY + NF++ PQ K V + ++L C PPE P +V+W+KN++ + ++ I + L+I + L+DSGNY+C+A ++ KR S A V + + NPA +WS W+ C+ C + RTR C+S C +N ++ V S++ + D+A+Y+ L + + ++ ++ +L +S Y +++ + S N T S NP ++++S+ ++LT R+Y + P C E + + D + S S + DH P V P +L + ++++ S P + T G GGRL +P +G++L + G+ S E+Y+ +++ + + L E LL P V +GP ++ + P ++VPH A + + NW N +L+ W+ + + + + T + +D ++LDQP LVG+ A KRL+L FG ++S+ NY +R+Y DT F+ V E G LL+ + F + NL I+++ W + T QE F +W +Q + +HC F + P+ L+C+I+ Q +Q++ + + + S++ F+I ++ R+++C D +G DW+ L ++L L+ L YF + SP+ +++LWE + + + L L +L+ IG+ L SD
Sbjct: 1 PEDAYIV-KSNPTKLRCRATPALQIFFKCNGEWVHQNEHMSHEYKDLITGLKVREVMIN----------------ISRQQVEDFHGPEDYWCLCVAWSHLGTSK------SRKATVRIAYLRKNFEQDPQGKEVPINRMIVLHCRPPEGVPAVEVEWLKNEELVSSMTDDNIDSRADQNLIINEARLSDSGNYTCLASNIVAKRRSATATVIVFVNGGWSLWTEWSPCNVPCGWGVQKRSRTCTNPAPLNGGAFCEGMSVQKIPCNALCPVDGGWDEWSEWTLCNSLCGRHRTRECSSPAPRHRGKMCEGNSEATENCTDGLYRNL-RHDVKPQSMEGSNDVALYLCLGAGIIAVAFLVVVV--------MLYRKSHSEYGVDVIDSSALTRGCQSF--NFKTTSQGNPLLLNSSMRSDLTVGRTYST--------PICFHESADKELFDPLPDIAVKVQSSFMISLGV--------------------ADHATFPDKV--------PAETYQRDLGCEYCSTMERRKKDTLMFSRPIAVDKEQPRTS--GVFGHQGGRLAVPSTGVSLLVPHGAVAEYMSCEVYMVINQGESSIETLEGCEILLGPEVTYGPSNLDLFCPAAVTVPHCAVVDKENW------------NIQLRRKTQDSKWEEVMLV--DEESTSCFCLMDSTCCHLLLDQPGSYALVGEPL-NQAAMKRLKLGVFGGLEASST---NYCLRVYCVDDTPHGFQRVVAAERTRGGQLLEEPKMLPFQANTFNLQVSIQDVPQFLWSIKPFTTCQEFSFSQVWCSNQ-QPMHCTFALERFSPATAQLSCKISVRQ--VKGHEQILQVYTAVAEGEKESPPFFMQTDCSVTSQTGP-------KAFKIPSSIRERICATFDTANAKGKDWQLLAQKLHLDRNLGYFAKQHSPSAVILSLWEVCHPDADDLDSLANALEEIGKIHSCILRPSD 871
BLAST of Netrin receptor UNC5B vs. Planmine SMEST
Match: SMESG000025091.1 (SMESG000025091.1) HSP 1 Score: 1937.15 bits (5017), Expect = 0.000e+0 Identity = 961/963 (99.79%), Postives = 962/963 (99.90%), Query Frame = 2
Query: 191 MWKYIFILAFFTKFSCTINPKAQIFGVKGNQPTREIEDENDFVKLNESKLEGIPSFIKEPESVYYVYEKKPAKIVCIAEPVSHVNIICNKEVFSYMDLELSESNLRVRKMNKNNEDDLTNGHRWMFSLEITYNQVTEWFNTFSCVCEAWNQIPSLRLAKKVHSRYGVIKEAYFKSNFKKVPQSKTVVKGQSLILTCVPPESKPKAQVQWMKNKKRLFENNRIKIVEEHQLLIEDTLLTDSGNYSCIAISLEEKRYSPIAIVKIQESVTENPATQWSAWSACDGNCKKTRTRNCNSKGVCKEIDSCTKKECEYNRAVAPFVKNPNKNGVSTSSLQDARDIAMYVGLFVAVTILVMVITIIFCLIRRKALLPLRSTMRYPLNINGNGVAYDVKNSLIKNSNTISTKNPYIMDTSLANLTQQRSYLSQSPPNLPPPTCLSEISSTNAYSTGIDFSYNSTGSGKFSQPLIXXXXXXXXXXXXXXXXXXXXDHKPDPLTVSGTPINSRPPSALYHELSLDRESICNSPPFVSENIDISTLAWGTISTIGGRLCLPQSGITLTIAPGSFINSSSSEMYLAVSRNDPNPPILSDNETLLTPIVLFGPKDVPILKPCVLSVPHSADLRQGNWVIRLLSCVLPDQNDELKEPLCQPIWKNIATIGCETDQTPIYTHLDPYAAFIMLDQPQKICLVGQSYPGGKATKRLRLAAFGRPLSTSSYLPNYNIRIYVFSDTKEAFESVSTIETKLGSTLLDITYQIIFSDSMGNLFFCIEELSTGWKSQLTTKYQEIPFQDIWSGSQSETLHCAFTFDNIDPSQQSLTCRITAYQSGFYNQKQVITIKQDKLDRSNHKRDLIQHEKVLLYSESNNTYLDPLMTVFRISNATRKKLCFLLDNVTPRGNDWKQLCRQLSLNGYLNYFMSKVSPTDALVTLWESRNRNENALIDLIISLKAIGRTDCSTLLESDCGSSSS 3079
MWKYIFILAFFTKFS TINPKAQIFGVKGNQPTREIEDENDFVKLNESKLEGIPSFIKEPESVYYVYEKKPAKIVCIAEPVSHVNIICNKEVFSYMDLELSESNLRVRKMNKNNEDDLTNGHRWMFSLEITYNQVTEWFNTFSCVCEAWNQIPSLRLAKKVHSRYGVIKEAYFKSNFKKVPQSKTVVKGQSLILTCVPPESKPKAQVQWMKNKKRLFENNRIKIVEEHQLLIEDTLLTDSGNYSCIAISLEEKRYSPIAIVKIQESVTENPATQWSAWSACDGNCKKTRTRNCNSKGVCKEIDSCTKKECEYNRAVAPFVKNPNKNGVSTSSLQDARDIAMYVGLFVAVTILVMVITIIFCLIRRKALLPLRSTMRYPLNINGNGVAYDVKNSLIKNSNTISTKNPYIMDTSLANLTQQRSYLSQSPPNLPPPTCLSEISSTNAYSTGIDFSYNSTGSGKFSQPLISNSSSASTTNKSKATSLSNTDHKPDPLTVSGTPINSRPPSALYHELSLDRESICNSPPFVSENIDISTLAWGTISTIGGRLCLPQSGITLTIAPGSFINSSSSEMYLAVSRNDPNPPILSDNETLLTPIVLFGPKDVPILKPCVLSVPHSADLRQGNWVIRLLSCVLPDQNDELKEPLCQPIWKNIATIGCETDQTPIYTHLDPYAAFIMLDQPQKICLVGQSYPGGKATKRLRLAAFGRPLSTSSYLPNYNIRIYVFSDTKEAFESVSTIETKLGSTLLDITYQIIFSDSMGNLFFCIEELSTGWKSQLTTKYQEIPFQDIWSGSQSETLHCAFTFDNIDPSQQSLTCRITAYQSGFY+QKQVITIKQDKLDRSNHKRDLIQHEKVLLYSESNNTYLDPLMTVFRISNATRKKLCFLLDNVTPRGNDWKQLCRQLSLNGYLNYFMSKVSPTDALVTLWESRNRNENALIDLIISLKAIGRTDCSTLLESDCGSSSS
Sbjct: 1 MWKYIFILAFFTKFSWTINPKAQIFGVKGNQPTREIEDENDFVKLNESKLEGIPSFIKEPESVYYVYEKKPAKIVCIAEPVSHVNIICNKEVFSYMDLELSESNLRVRKMNKNNEDDLTNGHRWMFSLEITYNQVTEWFNTFSCVCEAWNQIPSLRLAKKVHSRYGVIKEAYFKSNFKKVPQSKTVVKGQSLILTCVPPESKPKAQVQWMKNKKRLFENNRIKIVEEHQLLIEDTLLTDSGNYSCIAISLEEKRYSPIAIVKIQESVTENPATQWSAWSACDGNCKKTRTRNCNSKGVCKEIDSCTKKECEYNRAVAPFVKNPNKNGVSTSSLQDARDIAMYVGLFVAVTILVMVITIIFCLIRRKALLPLRSTMRYPLNINGNGVAYDVKNSLIKNSNTISTKNPYIMDTSLANLTQQRSYLSQSPPNLPPPTCLSEISSTNAYSTGIDFSYNSTGSGKFSQPLISNSSSASTTNKSKATSLSNTDHKPDPLTVSGTPINSRPPSALYHELSLDRESICNSPPFVSENIDISTLAWGTISTIGGRLCLPQSGITLTIAPGSFINSSSSEMYLAVSRNDPNPPILSDNETLLTPIVLFGPKDVPILKPCVLSVPHSADLRQGNWVIRLLSCVLPDQNDELKEPLCQPIWKNIATIGCETDQTPIYTHLDPYAAFIMLDQPQKICLVGQSYPGGKATKRLRLAAFGRPLSTSSYLPNYNIRIYVFSDTKEAFESVSTIETKLGSTLLDITYQIIFSDSMGNLFFCIEELSTGWKSQLTTKYQEIPFQDIWSGSQSETLHCAFTFDNIDPSQQSLTCRITAYQSGFYSQKQVITIKQDKLDRSNHKRDLIQHEKVLLYSESNNTYLDPLMTVFRISNATRKKLCFLLDNVTPRGNDWKQLCRQLSLNGYLNYFMSKVSPTDALVTLWESRNRNENALIDLIISLKAIGRTDCSTLLESDCGSSSS 963
BLAST of Netrin receptor UNC5B vs. Planmine SMEST
Match: SMESG000025091.1 (SMESG000025091.1) HSP 1 Score: 1891.7 bits (4899), Expect = 0.000e+0 Identity = 944/963 (98.03%), Postives = 946/963 (98.23%), Query Frame = 2
Query: 191 MWKYIFILAFFTKFSCTINPKAQIFGVKGNQPTREIEDENDFVKLNESKLEGIPSFIKEPESVYYVYEKKPAKIVCIAEPVSHVNIICNKEVFSYMDLELSESNLRVRKMNKNNEDDLTNGHRWMFSLEITYNQVTEWFNTFSCVCEAWNQIPSLRLAKKVHSRYGVIKEAYFKSNFKKVPQSKTVVKGQSLILTCVPPESKPKAQVQWMKNKKRLFENNRIKIVEEHQLLIEDTLLTDSGNYSCIAISLEEKRYSPIAIVKIQESVTENPATQWSAWSACDGNCKKTRTRNCNSKGVCKEIDSCTKKECEYNRAVAPFVKNPNKNGVSTSSLQDARDIAMYVGLFVAVTILVMVITIIFCLIRRKALLPLRSTMRYPLNINGNGVAYDVKNSLIKNSNTISTKNPYIMDTSLANLTQQRSYLSQSPPNLPPPTCLSEISSTNAYSTGIDFSYNSTGSGKFSQPLIXXXXXXXXXXXXXXXXXXXXDHKPDPLTVSGTPINSRPPSALYHELSLDRESICNSPPFVSENIDISTLAWGTISTIGGRLCLPQSGITLTIAPGSFINSSSSEMYLAVSRNDPNPPILSDNETLLTPIVLFGPKDVPILKPCVLSVPHSADLRQGNWVIRLLSCVLPDQNDELKEPLCQPIWKNIATIGCETDQTPIYTHLDPYAAFIMLDQPQKICLVGQSYPGGKATKRLRLAAFGRPLSTSSYLPNYNIRIYVFSDTKEAFESVSTIETKLGSTLLDITYQIIFSDSMGNLFFCIEELSTGWKSQLTTKYQEIPFQDIWSGSQSETLHCAFTFDNIDPSQQSLTCRITAYQSGFYNQKQVITIKQDKLDRSNHKRDLIQHEKVLLYSESNNTYLDPLMTVFRISNATRKKLCFLLDNVTPRGNDWKQLCRQLSLNGYLNYFMSKVSPTDALVTLWESRNRNENALIDLIISLKAIGRTDCSTLLESDCGSSSS 3079
MWKYIFILAFFTKFS TINPKAQIFGVKGNQPTREIEDENDFVKLNESKLEGIPSFIKEPESVYYVYEKKPAKIVCIAEPVSHVNIICNKEVFSYMDLELSESNLRVRKMNKNNEDDLTNGHRWMFSLEITYNQVTEWFNTFSCVCEAWNQIPSLRLAKKVHSRYGVIKEAYFKSNFKKVPQSKTVVKGQSLILTCVPPESKPKAQVQWMKNKKRLFENNRIKIVEEHQLLIEDTLLTDSGNYSCIAISLEEKRYSPIAIVKIQESVTENPATQWSAWSACDGNCKKTRTRNCNSKGVCKEIDSCTKKECE +STSSLQDARDIAMYVGLFVAVTILVMVITIIFCLIRRKALLPLRSTMRYPLNINGNGVAYDVKNSLIKNSNTISTKNPYIMDTSLANLTQQRSYLSQSPPNLPPPTCLSEISSTNAYSTGIDFSYNSTGSGKFSQPLISNSSSASTTNKSKATSLSNTDHKPDPLTVSGTPINSRPPSALYHELSLDRESICNSPPFVSENIDISTLAWGTISTIGGRLCLPQSGITLTIAPGSFINSSSSEMYLAVSRNDPNPPILSDNETLLTPIVLFGPKDVPILKPCVLSVPHSADLRQGNWVIRLLSCVLPDQNDELKEPLCQPIWKNIATIGCETDQTPIYTHLDPYAAFIMLDQPQKICLVGQSYPGGKATKRLRLAAFGRPLSTSSYLPNYNIRIYVFSDTKEAFESVSTIETKLGSTLLDITYQIIFSDSMGNLFFCIEELSTGWKSQLTTKYQEIPFQDIWSGSQSETLHCAFTFDNIDPSQQSLTCRITAYQSGFY+QKQVITIKQDKLDRSNHKRDLIQHEKVLLYSESNNTYLDPLMTVFRISNATRKKLCFLLDNVTPRGNDWKQLCRQLSLNGYLNYFMSKVSPTDALVTLWESRNRNENALIDLIISLKAIGRTDCSTLLESDCGSSSS
Sbjct: 1 MWKYIFILAFFTKFSWTINPKAQIFGVKGNQPTREIEDENDFVKLNESKLEGIPSFIKEPESVYYVYEKKPAKIVCIAEPVSHVNIICNKEVFSYMDLELSESNLRVRKMNKNNEDDLTNGHRWMFSLEITYNQVTEWFNTFSCVCEAWNQIPSLRLAKKVHSRYGVIKEAYFKSNFKKVPQSKTVVKGQSLILTCVPPESKPKAQVQWMKNKKRLFENNRIKIVEEHQLLIEDTLLTDSGNYSCIAISLEEKRYSPIAIVKIQESVTENPATQWSAWSACDGNCKKTRTRNCNSKGVCKEIDSCTKKECE----------------LSTSSLQDARDIAMYVGLFVAVTILVMVITIIFCLIRRKALLPLRSTMRYPLNINGNGVAYDVKNSLIKNSNTISTKNPYIMDTSLANLTQQRSYLSQSPPNLPPPTCLSEISSTNAYSTGIDFSYNSTGSGKFSQPLISNSSSASTTNKSKATSLSNTDHKPDPLTVSGTPINSRPPSALYHELSLDRESICNSPPFVSENIDISTLAWGTISTIGGRLCLPQSGITLTIAPGSFINSSSSEMYLAVSRNDPNPPILSDNETLLTPIVLFGPKDVPILKPCVLSVPHSADLRQGNWVIRLLSCVLPDQNDELKEPLCQPIWKNIATIGCETDQTPIYTHLDPYAAFIMLDQPQKICLVGQSYPGGKATKRLRLAAFGRPLSTSSYLPNYNIRIYVFSDTKEAFESVSTIETKLGSTLLDITYQIIFSDSMGNLFFCIEELSTGWKSQLTTKYQEIPFQDIWSGSQSETLHCAFTFDNIDPSQQSLTCRITAYQSGFYSQKQVITIKQDKLDRSNHKRDLIQHEKVLLYSESNNTYLDPLMTVFRISNATRKKLCFLLDNVTPRGNDWKQLCRQLSLNGYLNYFMSKVSPTDALVTLWESRNRNENALIDLIISLKAIGRTDCSTLLESDCGSSSS 947
BLAST of Netrin receptor UNC5B vs. Planmine SMEST
Match: SMESG000040323.1 (SMESG000040323.1) HSP 1 Score: 432.95 bits (1112), Expect = 2.341e-134 Identity = 332/1039 (31.95%), Postives = 505/1039 (48.60%), Query Frame = 2
Query: 290 REIEDENDFVKLNESKLEGIPSFIKEPESVYYVYEKKPAKIVCIAEPVSHVNIICNKEVFSYMDLELSESNLRVRKMNKNNEDDLT-NGHRWMFSLEITYNQVTEWFNTFSCVCEAWNQIPSLRLAKKVHSRYGVIKEAYFKSNFKKVPQSKTVVKGQSLILTCVPPESKPKAQVQWMKNKKRLFENN--RIKIVEEHQLLIEDTLLTDSGNYSCIAISLEEKRYSPIAIVKIQESVTENPATQWSAWSACDGNC-----------------KKTRTRNCNSKGVCKEIDSCTKKECEYNRA--------------VAPFVKNP-----------NKNGVSTSSLQDARDIAM---YVGLFV-------------------AVTILVMVITIIFCL--------IRRKAL-LPLRSTMRYPLNINGNGVAYDVKNSLIKNSNTISTKNPYIMDTSLANLTQQRSYLSQSPPNLPP--PTCLSEISSTNAYS-TGIDFSYNSTGS----GKFSQPLIXXXXXXXXXXXXXXXXXXXXDHKPD---PLTVSGTPIN-SRPPSALYHEL-SLDRESICNS--PPFVSENIDISTLAWGTISTIGGRLCLPQSGITLTIAPGSFINSSSSEMYLAVSRNDPNPPILSDNETLLTPIVLFGPKDVPILKPCVLSVPHSA-DLRQGNWVIRLLSCVLPDQNDELKEPLCQPIWKNIATIGCE-TDQTPIYTHLDPYAAFIMLDQPQKICLVGQSYPGGKATKRLRLAAFGRPLSTSSYLPNYNIRIYVFSDTKEAFESVSTIET-KLGSTLLDITYQIIFSDSMGNLFFCIEELSTGWKSQLTTKYQEIPFQDIWSGSQSETLHCAFTF----DNIDPSQQSLT---------CRITAYQSGFYNQKQVITIKQDKLDRSNHKRDLIQHEKVLLYSESNNT----YLDP-----LMTVFRISNATRKKLCFLLDNVTPRGNDWKQLCRQLSLNGYLNYFMSKVSPTDALVTLWESRNRNENALIDLIISLKAIGRTDCSTLLESD 3061
E++ + D V +E LEG+P FI++P+S+YYV + PA I CIA+PVSHVNI C + +SYM+ E+S + L+V KM+ NE L G+RW FSLE+ + V EWF+ + C CEAWNQI L+ KKV S VI ++Y +FK VP+++ V S+ L+C+PP++KP A++ W+KN +++ + + +I E +LL+ + LTDSGNYSC+A S +R++ I+ + QWS WS G C ++ R R CN + + +C E EY R + NP N G ++S D +A +V F+ A+ I + V +F + IRR+ + RY NG + Y KN L KN + +S K ++D + Q Y S PN P P+ S+ SS +AY+ G D +Y + PL+S+ S + S ++ P VS PI S S Y EL + D E+ S P + N + + W TI + GGR+ L S I LT P SF S ++LA ++ + P LS NETLL+P+V+ GP +V KP +L++PH A + GNW I +L+ P LK+ +P W+ + E D P Y L F++ +Q Q+ C+VG SY +ATK LR+AA+ L +R+Y+ D E V ET +LG+ L+ Q D GN+ I +L+ W++ YQEIPF+D+W S TLHC+F F N + S+ ++ C ++ YQ+ ++ KQ + + + S+H + YS + ++D +VF++ T+ KLC LLD++TP NDW+QL R LS+ L +F +K+S T+ L+ LWE++N + +L +LI L+ +GR DC +LE D
Sbjct: 35 HEVDSKKDLVLPSEKHLEGVPKFIQQPKSMYYVSKSHPAVITCIAQPVSHVNIFCADKQYSYMNEEVSATGLKVIKMD--NEGRLAVKGNRWKFSLEVQHKDVIEWFSEYRCHCEAWNQIEQLQKVKKVESSSAVIYDSYINKDFKTVPKNQKVSVRGSVKLSCIPPDAKPPAEIHWVKNGEKITGKSHPQFEINEYGELLLSNIRLTDSGNYSCVASSFGLERHATAQILVFE-------VGQWSDWSEWTGICPNICSKGSNCPKVCSTSRQQRVRYCNQ--INNQKANCIGSEIEYKRCDLICDSNLWTFWSEWSKCSGNPCKKERTRQCTTNNCGKASSVEIDNCTLAECGGFVASFINSNKKYPESSTSIYITHDVAMYIGLFVAVSVFLMVVAIIFCLIRRRVIGFSPNRVWRYSTTANGIQMFYPDKN-LKKNLSNLSNKQINLID-----INQPSLYRSIVLPNSLPFLPSNQSDASSNSAYTDVGNDITYIQRNHLPSLPMIATPLLSSMKPTLKIRPSYSDSKVSSTLYPQMGLVKHVSTLPIPVSSSLSDHYQELGNTDNETSDQSVTEPCLPYNFNGENMIWATIDSSGGRISLALSDINLTCPPNSFAPGISEPIFLATCNSEQDLPNLSTNETLLSPVVVCGPTNVIAFKPFILNIPHCAYNTDSGNWAISVLTSYSP-----LKQ---KPYWQKYLDLDAEDKDSPPGYAQLAKDRLFLITNQLQRFCVVGSSYRNKRATKVLRIAAYCTGLDRRHADEQIVVRLYLIPDIAECISKVHNFETNRLGARLVTNQKQFFCEDEAGNITVVISDLAMDWQASSANNYQEIPFKDVW---HSPTLHCSFNFIKRLINANSSELKISVNSLDFNWFCTLSIYQTNSHHNKQTVLLSTP--NGSSHTSISATSTQFSNYSAGGSQSFPYFVDDCSKTNFESVFKLPEQTKIKLCKLLDSLTPLDNDWRQLARHLSITRSLQFFSNKLSSTEILLDLWEAQNHSRKSLNNLIDILRKMGRLDCVAILEKD 1043
BLAST of Netrin receptor UNC5B vs. Planmine SMEST
Match: SMESG000046884.1 (SMESG000046884.1) HSP 1 Score: 397.897 bits (1021), Expect = 9.688e-123 Identity = 283/932 (30.36%), Postives = 455/932 (48.82%), Query Frame = 2
Query: 305 ENDFVKLNESKLEGIPSFIKEPESVYYVYEKKPAKIVCIAEPVSHVNIICNKEVFSYMDLELSESNLRVRKMNKNNEDDLTNGHRWMFSLEITYNQVTEWFNTFSCVCEAWNQIPSLRLAKKVHSRYGVIKEAYFKSNFKKVPQSKTVVKGQSLILTCVPPESKPKAQVQWMKNKKRLFENN--RIKIVEEHQLLIEDTLLTDSGNYSCIAISLEEKRYSPIAIVKIQESVTENPATQWSAWSACDGNCKKTRTRNCNSKGVCKEIDSCTKKECEYNRAVAPFVKNPNKNGVSTSSLQDARDIAMYVGLFVAVTILVMVITIIFCLIRRKALLPLRSTMRYPLNINGNGVAYDVKNSLIKNSNTISTKNPYIMD-------TSLANLTQQRSYLSQSPPNLPPPTCLSEISSTNAYSTGIDFSYNSTGSGKFSQPLIXXXXXXXXXXXXXXXXXXXXDHKPDPLTVSGTPINSRPPSALYHELSLDRESICNSPPFVSENIDISTLAWGTISTIGGRLCLPQSGITLTIAPGSFINSSSSEMYLAVSRNDPNPPILSDNETLLTPIVLFGPKDVPILKPCVLSVPHSADLRQGNWVIRLLSCVLPDQNDELKEPLCQPIWKNIATIGCETDQTPIYTHLDPYAAFIMLDQPQKICLVGQ--SYPGGKATKRLRLAAFGRPLSTSSYLPNYNIRIYVFSDTKEAFESVSTIETKLGSTLLDITYQIIFSDSMGNLFFCIEELSTGWKSQLTTKYQEIPFQDIWSGSQSETLHCAFTFDNIDPSQQSLTCRITAYQSGFYNQKQVITIKQDKLDRSNHKRDLIQHEKVLLYSESNNTYLDPLMTVFRISNATRKKLCFLLDNVTPRGNDWKQLCRQLSLNGYLNYFMSKVSPTDALVTLWESRNRNENALIDLIISLKAIGRTDCSTLLESDCG 3067
+ D + E LEG+P F+ + YYV I C+A+PVSH NIIC + FSYM +S++ L V K N++N+ D G +W SL + + V+EWF+ + CVCEAWNQIP+L AKKV SR I E+YF+SNFK++P S+ ++ Q L L CVPP +KP A V W+KNKK++ E IK++++ L+IE+ +D G Y C A SL+ R SP A + + ES+ + + + + RTR C +I C + +Y R + + + S ++ D + +Y+ L + V +L + + RRK LL LN+ + D N + +IS+ ++D ++ + + LS NL P S+ N+ + + Y+S+ + I S + + TPIN+ L + ES+ N + N +AWGT S+IGG L +P+SG++L I + S ++L VSR + PIL+DNE LL+P+++ GP+ V K +L VPH+A + W RLL + ++ +P W+ ++T + +Y H+ + IML C++GQ S KA+ +++ F NY+IRIY +TKEAFES+ +E K G L + + F D NL I E++ GWK T + Q + FQ +W S + +F FD S S +C + AYQ+G Y+ + + +K K ++ +K + + ++ P+ F +S+ T+K+L LL P GNDW+ L R++++ YF+ K PTD+L+ LW+++N + + DL+ + R DC ++LE + G
Sbjct: 20 QTDLILPEEMDLEGVPKFLVQLREFYYVKSDHSVTISCMADPVSHANIICATKQFSYMGRPVSDTGLIVTKFNRSNQID-PQGTKWNISLIVDHKSVSEWFSKYECVCEAWNQIPALGRAKKVFSRTSTILESYFRSNFKRIPISQNLLVNQKLELECVPPNAKPTAFVIWLKNKKKINEAVFPHIKVIDQSSLIIENVTESDIGQYCCEAYSLDIVRKSPCADINVIESLKWSSWSFCDSSCS------SFRTRGC-------QISLCQISDIQY-RNCSSY------SCWSMGNVLDQFENVIYISLSILVFLLFAIFLAVVFTFRRKHLLK----KSRDLNVKSKAIKADPNNENLHACRSISSSTDCMVDELRSIPNSNHLQASNRNKTLSIDSENLVP------YSAINSDTVDVGTCYHSSCLSTEGRSFIPKDVGLSI-------------FNSSSSSSAQTPINN---------LFVYDESLYNVLTTKTNN-SFDGMAWGTFSSIGGHLDIPESGVSLFIPRDAIPIGLSQRIFLTVSRCSAHKPILNDNEALLSPVIICGPEIVDFEKSVILIVPHNAAVTHSQWHFRLLRSKYVNSSE-------KPDWEILSTTNNDDFGQHVYIHVTREKSCIMLKSLDMYCVIGQPLSTNSNKASIFIQIIVFSENFYQEC--DNYSIRIYTIPNTKEAFESIYFVENKSGGKLWSCSKNLNFFDGGENLILRINEIAKGWKINQTPQTQLVKFQTVWKSHDSLGIMNSFHFDRSSSSLNSFSCSLVAYQNGNYSNRVTLELKSGKSINHSNSSFSRSSDKTVNNDSTAYPFIHPIFENFSLSSQTKKELSKLLKIYDPSGNDWRILAREMNIKK-TEYFL-KEDPTDSLLNLWQAQNPQKFYIKDLMSVFQRYKRFDCVSVLERNEG 886
BLAST of Netrin receptor UNC5B vs. Planmine SMEST
Match: SMESG000046884.1 (SMESG000046884.1) HSP 1 Score: 395.586 bits (1015), Expect = 6.367e-122 Identity = 282/932 (30.26%), Postives = 456/932 (48.93%), Query Frame = 2
Query: 305 ENDFVKLNESKLEGIPSFIKEPESVYYVYEKKPAKIVCIAEPVSHVNIICNKEVFSYMDLELSESNLRVRKMNKNNEDDLTNGHRWMFSLEITYNQVTEWFNTFSCVCEAWNQIPSLRLAKKVHSRYGVIKEAYFKSNFKKVPQSKTVVKGQSLILTCVPPESKPKAQVQWMKNKKRLFENN--RIKIVEEHQLLIEDTLLTDSGNYSCIAISLEEKRYSPIAIVKIQESVTENPATQWSAWSACDGNCKKTRTRNCNSKGVCKEIDSCTKKECEYNRAVAPFVKNPNKNGVSTSSLQDARDIAMYVGLFVAVTILVMVITIIFCLIRRKALLPLRSTMRYPLNINGNGVAYDVKNSLIKNSNTISTKNPYIMD-------TSLANLTQQRSYLSQSPPNLPPPTCLSEISSTNAYSTGIDFSYNSTGSGKFSQPLIXXXXXXXXXXXXXXXXXXXXDHKPDPLTVSGTPINSRPPSALYHELSLDRESICNSPPFVSENIDISTLAWGTISTIGGRLCLPQSGITLTIAPGSFINSSSSEMYLAVSRNDPNPPILSDNETLLTPIVLFGPKDVPILKPCVLSVPHSADLRQGNWVIRLLSCVLPDQNDELKEPLCQPIWKNIATIGCETDQTPIYTHLDPYAAFIMLDQPQKICLVGQ--SYPGGKATKRLRLAAFGRPLSTSSYLPNYNIRIYVFSDTKEAFESVSTIETKLGSTLLDITYQIIFSDSMGNLFFCIEELSTGWKSQLTTKYQEIPFQDIWSGSQSETLHCAFTFDNIDPSQQSLTCRITAYQSGFYNQKQVITIKQDKLDRSNHKRDLIQHEKVLLYSESNNTYLDPLMTVFRISNATRKKLCFLLDNVTPRGNDWKQLCRQLSLNGYLNYFMSKVSPTDALVTLWESRNRNENALIDLIISLKAIGRTDCSTLLESDCG 3067
+ D + E LEG+P F+ + YYV I C+A+PVSH NIIC + FSYM +S++ L V K N++N+ D G +W SL + + V+EWF+ + CVCEAWNQIP+L AKKV SR I E+YF+SNFK++P S+ ++ Q L L CVPP +KP A V W+KNKK++ E IK++++ L+IE+ +D G Y C A SL+ R SP A + + ES+ + + + + RTR C +I C + +Y R + + + S ++ D + +Y+ L + V +L + + RRK L L+ + + G + D N + +IS+ ++D ++ + + LS NL P S+ N+ + + Y+S+ + I S + + TPIN+ L + ES+ N + N +AWGT S+IGG L +P+SG++L I + S ++L VSR + PIL+DNE LL+P+++ GP+ V K +L VPH+A + W RLL + ++ +P W+ ++T + +Y H+ + IML C++GQ S KA+ +++ F NY+IRIY +TKEAFES+ +E K G L + + F D NL I E++ GWK T + Q + FQ +W S + +F FD S S +C + AYQ+G Y+ + + +K K ++ +K + + ++ P+ F +S+ T+K+L LL P GNDW+ L R++++ YF+ K PTD+L+ LW+++N + + DL+ + R DC ++LE + G
Sbjct: 20 QTDLILPEEMDLEGVPKFLVQLREFYYVKSDHSVTISCMADPVSHANIICATKQFSYMGRPVSDTGLIVTKFNRSNQID-PQGTKWNISLIVDHKSVSEWFSKYECVCEAWNQIPALGRAKKVFSRTSTILESYFRSNFKRIPISQNLLVNQKLELECVPPNAKPTAFVIWLKNKKKINEAVFPHIKVIDQSSLIIENVTESDIGQYCCEAYSLDIVRKSPCADINVIESLKWSSWSFCDSSCS------SFRTRGC-------QISLCQISDIQY-RNCSSY------SCWSMGNVLDQFENVIYISLSILVFLLFAIFLAVVFTFRRKHL--LKKSRDLNVKSKGKTIKADPNNENLHACRSISSSTDCMVDELRSIPNSNHLQASNRNKTLSIDSENLVP------YSAINSDTVDVGTCYHSSCLSTEGRSFIPKDVGLSI-------------FNSSSSSSAQTPINN---------LFVYDESLYNVLTTKTNN-SFDGMAWGTFSSIGGHLDIPESGVSLFIPRDAIPIGLSQRIFLTVSRCSAHKPILNDNEALLSPVIICGPEIVDFEKSVILIVPHNAAVTHSQWHFRLLRSKYVNSSE-------KPDWEILSTTNNDDFGQHVYIHVTREKSCIMLKSLDMYCVIGQPLSTNSNKASIFIQIIVFSENFYQEC--DNYSIRIYTIPNTKEAFESIYFVENKSGGKLWSCSKNLNFFDGGENLILRINEIAKGWKINQTPQTQLVKFQTVWKSHDSLGIMNSFHFDRSSSSLNSFSCSLVAYQNGNYSNRVTLELKSGKSINHSNSSFSRSSDKTVNNDSTAYPFIHPIFENFSLSSQTKKELSKLLKIYDPSGNDWRILAREMNIKK-TEYFL-KEDPTDSLLNLWQAQNPQKFYIKDLMSVFQRYKRFDCVSVLERNEG 888 The following BLAST results are available for this feature:
BLAST of Netrin receptor UNC5B vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Netrin receptor UNC5B vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Netrin receptor UNC5B vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Netrin receptor UNC5B vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Netrin receptor UNC5B vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Netrin receptor UNC5B vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Netrin receptor UNC5B vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Netrin receptor UNC5B vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Netrin receptor UNC5B vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Netrin receptor UNC5B vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Netrin receptor UNC5B vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Netrin receptor UNC5B vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Netrin receptor UNC5B vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Netrin receptor UNC5B vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30019501 ID=SMED30019501|Name=Netrin receptor UNC5B|organism=Schmidtea mediterranea sexual|type=transcript|length=3167bpback to top protein sequence of SMED30019501-orf-1 >SMED30019501-orf-1 ID=SMED30019501-orf-1|Name=SMED30019501-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=964bp MWKYIFILAFFTKFSCTINPKAQIFGVKGNQPTREIEDENDFVKLNESKLback to top Annotated Terms
The following terms have been associated with this transcript:
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