N-acetyltransferase domain-containing protein
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30019398 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 5
Homology
BLAST of N-acetyltransferase domain-containing protein vs. Ensembl Human
Match: NAA50 (N(alpha)-acetyltransferase 50, NatE catalytic subunit [Source:HGNC Symbol;Acc:HGNC:29533]) HSP 1 Score: 48.1358 bits (113), Expect = 8.767e-6 Identity = 28/90 (31.11%), Postives = 51/90 (56.67%), Query Frame = 1 Query: 766 VEPESISEVGFENQI-IAAISFKLRHIDVRKIVHVTMLGVLKEYRSKGIGKHLINLVLD-QKIVGKYDAVVVHADFS---ACDFFKKFGF 1020 +E ++++ + N I + A+ ++ H +K +++ LG L YR GIG ++N VL+ + G +D + +H S A DF++KFGF Sbjct: 40 LEVGELAKLAYFNDIAVGAVCCRVDHSQNQKRLYIMTLGCLAPYRRLGIGTKMLNHVLNICEKDGTFDNIYLHVQISNESAIDFYRKFGF 129
BLAST of N-acetyltransferase domain-containing protein vs. Ensembl Human
Match: NAA50 (N(alpha)-acetyltransferase 50, NatE catalytic subunit [Source:HGNC Symbol;Acc:HGNC:29533]) HSP 1 Score: 48.1358 bits (113), Expect = 8.792e-6 Identity = 28/90 (31.11%), Postives = 51/90 (56.67%), Query Frame = 1 Query: 766 VEPESISEVGFENQI-IAAISFKLRHIDVRKIVHVTMLGVLKEYRSKGIGKHLINLVLD-QKIVGKYDAVVVHADFS---ACDFFKKFGF 1020 +E ++++ + N I + A+ ++ H +K +++ LG L YR GIG ++N VL+ + G +D + +H S A DF++KFGF Sbjct: 39 LEVGELAKLAYFNDIAVGAVCCRVDHSQNQKRLYIMTLGCLAPYRRLGIGTKMLNHVLNICEKDGTFDNIYLHVQISNESAIDFYRKFGF 128
BLAST of N-acetyltransferase domain-containing protein vs. Ensembl Zebrafish
Match: si:dkeyp-50b9.1 (si:dkeyp-50b9.1 [Source:ZFIN;Acc:ZDB-GENE-131127-254]) HSP 1 Score: 96.6709 bits (239), Expect = 8.799e-21 Identity = 54/166 (32.53%), Postives = 97/166 (58.43%), Query Frame = 1 Query: 784 SEVGFENQIIAAISFKLRHI-DVRKIVHVTMLGVLKEYRSKGIGKHLINLVLDQKIVGKYDAVVVHADFSACDFFKKFGFSDDPILNIQWHTLEPEYTNCSLLTYLPSYSNQDRENKLLAEEFSTAEMEVDIKLWQKKMTEVHCFQFQ--TFQRMKMEIQHLKETI 1272 S VG E+ I+AA ++L+ + K++ +++L V K YR +GIG +++ L+ Q +VG+YD +V HAD FF GFSDD +LN + L+ E+TN +++YLP ++ + + +FS + EV+I+L + + +Q Q R+ E++ L++ + Sbjct: 184 SAVGVESLIVAAACYELKTLFTGNKVLQLSLLAVRKNYRHQGIGSYIVQLLKSQSVVGQYDTLVAHADTDTTAFFNSNGFSDDLMLNDMFKELKDEWTNSIIMSYLPPFTT---DLTMRDPDFSLSLQEVEIELKTARSQALCAYQQQMVCVTRLLKEVKILRQQL 346
BLAST of N-acetyltransferase domain-containing protein vs. Ensembl Zebrafish
Match: si:dkeyp-50b9.1 (si:dkeyp-50b9.1 [Source:ZFIN;Acc:ZDB-GENE-131127-254]) HSP 1 Score: 96.6709 bits (239), Expect = 8.799e-21 Identity = 54/166 (32.53%), Postives = 97/166 (58.43%), Query Frame = 1 Query: 784 SEVGFENQIIAAISFKLRHI-DVRKIVHVTMLGVLKEYRSKGIGKHLINLVLDQKIVGKYDAVVVHADFSACDFFKKFGFSDDPILNIQWHTLEPEYTNCSLLTYLPSYSNQDRENKLLAEEFSTAEMEVDIKLWQKKMTEVHCFQFQ--TFQRMKMEIQHLKETI 1272 S VG E+ I+AA ++L+ + K++ +++L V K YR +GIG +++ L+ Q +VG+YD +V HAD FF GFSDD +LN + L+ E+TN +++YLP ++ + + +FS + EV+I+L + + +Q Q R+ E++ L++ + Sbjct: 184 SAVGVESLIVAAACYELKTLFTGNKVLQLSLLAVRKNYRHQGIGSYIVQLLKSQSVVGQYDTLVAHADTDTTAFFNSNGFSDDLMLNDMFKELKDEWTNSIIMSYLPPFTT---DLTMRDPDFSLSLQEVEIELKTARSQALCAYQQQMVCVTRLLKEVKILRQQL 346
BLAST of N-acetyltransferase domain-containing protein vs. Ensembl Zebrafish
Match: naa50 (N(alpha)-acetyltransferase 50, NatE catalytic subunit [Source:NCBI gene;Acc:445229]) HSP 1 Score: 47.7506 bits (112), Expect = 7.764e-6 Identity = 28/90 (31.11%), Postives = 51/90 (56.67%), Query Frame = 1 Query: 766 VEPESISEVGFENQI-IAAISFKLRHIDVRKIVHVTMLGVLKEYRSKGIGKHLINLVLD-QKIVGKYDAVVVHADFS---ACDFFKKFGF 1020 +E ++++ + N I + A+ ++ H +K +++ LG L YR GIG ++N VL+ + G +D + +H S A DF++KFGF Sbjct: 37 LEVGELAKLAYFNDIAVGAVCCRVDHSQNQKRLYIMTLGCLAPYRRLGIGTKMLNHVLNICEKDGTFDNIYLHVQISNESAIDFYQKFGF 126
BLAST of N-acetyltransferase domain-containing protein vs. Ensembl Zebrafish
Match: naa50 (N(alpha)-acetyltransferase 50, NatE catalytic subunit [Source:NCBI gene;Acc:445229]) HSP 1 Score: 47.7506 bits (112), Expect = 8.815e-6 Identity = 28/90 (31.11%), Postives = 51/90 (56.67%), Query Frame = 1 Query: 766 VEPESISEVGFENQI-IAAISFKLRHIDVRKIVHVTMLGVLKEYRSKGIGKHLINLVLD-QKIVGKYDAVVVHADFS---ACDFFKKFGF 1020 +E ++++ + N I + A+ ++ H +K +++ LG L YR GIG ++N VL+ + G +D + +H S A DF++KFGF Sbjct: 39 LEVGELAKLAYFNDIAVGAVCCRVDHSQNQKRLYIMTLGCLAPYRRLGIGTKMLNHVLNICEKDGTFDNIYLHVQISNESAIDFYQKFGF 128
BLAST of N-acetyltransferase domain-containing protein vs. Ensembl Zebrafish
Match: naa50 (N(alpha)-acetyltransferase 50, NatE catalytic subunit [Source:NCBI gene;Acc:445229]) HSP 1 Score: 47.7506 bits (112), Expect = 8.872e-6 Identity = 28/90 (31.11%), Postives = 51/90 (56.67%), Query Frame = 1 Query: 766 VEPESISEVGFENQI-IAAISFKLRHIDVRKIVHVTMLGVLKEYRSKGIGKHLINLVLD-QKIVGKYDAVVVHADFS---ACDFFKKFGF 1020 +E ++++ + N I + A+ ++ H +K +++ LG L YR GIG ++N VL+ + G +D + +H S A DF++KFGF Sbjct: 40 LEVGELAKLAYFNDIAVGAVCCRVDHSQNQKRLYIMTLGCLAPYRRLGIGTKMLNHVLNICEKDGTFDNIYLHVQISNESAIDFYQKFGF 129
BLAST of N-acetyltransferase domain-containing protein vs. Ensembl Xenopus
Match: cdk1 (cyclin-dependent kinase 1 [Source:Xenbase;Acc:XB-GENE-482750]) HSP 1 Score: 48.521 bits (114), Expect = 6.836e-6 Identity = 28/90 (31.11%), Postives = 51/90 (56.67%), Query Frame = 1 Query: 766 VEPESISEVGFENQI-IAAISFKLRHIDVRKIVHVTMLGVLKEYRSKGIGKHLINLVLD-QKIVGKYDAVVVHADFS---ACDFFKKFGF 1020 +E ++++ + N I + A+ ++ H +K +++ LG L YR GIG ++N VL+ + G +D + +H S A DF++KFGF Sbjct: 35 LEVGELAKLAYFNDIAVGAVCCRVDHSQNQKRLYIMTLGCLAPYRRLGIGTKMLNHVLNICEKDGTFDNIYLHVQISNESAIDFYRKFGF 124
BLAST of N-acetyltransferase domain-containing protein vs. Ensembl Xenopus
Match: cdk1 (cyclin-dependent kinase 1 [Source:Xenbase;Acc:XB-GENE-482750]) HSP 1 Score: 48.521 bits (114), Expect = 7.161e-6 Identity = 28/90 (31.11%), Postives = 51/90 (56.67%), Query Frame = 1 Query: 766 VEPESISEVGFENQI-IAAISFKLRHIDVRKIVHVTMLGVLKEYRSKGIGKHLINLVLD-QKIVGKYDAVVVHADFS---ACDFFKKFGF 1020 +E ++++ + N I + A+ ++ H +K +++ LG L YR GIG ++N VL+ + G +D + +H S A DF++KFGF Sbjct: 39 LEVGELAKLAYFNDIAVGAVCCRVDHSQNQKRLYIMTLGCLAPYRRLGIGTKMLNHVLNICEKDGTFDNIYLHVQISNESAIDFYRKFGF 128
BLAST of N-acetyltransferase domain-containing protein vs. Ensembl Mouse
Match: Naa50 (N(alpha)-acetyltransferase 50, NatE catalytic subunit [Source:MGI Symbol;Acc:MGI:1919367]) HSP 1 Score: 48.521 bits (114), Expect = 5.138e-6 Identity = 28/90 (31.11%), Postives = 51/90 (56.67%), Query Frame = 1 Query: 766 VEPESISEVGFENQI-IAAISFKLRHIDVRKIVHVTMLGVLKEYRSKGIGKHLINLVLD-QKIVGKYDAVVVHADFS---ACDFFKKFGF 1020 +E ++++ + N I + A+ ++ H +K +++ LG L YR GIG ++N VL+ + G +D + +H S A DF++KFGF Sbjct: 39 LEVGELAKLAYFNDIAVGAVCCRVDHSQNQKRLYIMTLGCLAPYRRLGIGTKMLNHVLNICEKDGTFDNIYLHVQISNESAIDFYRKFGF 128
BLAST of N-acetyltransferase domain-containing protein vs. Ensembl Mouse
Match: Naa50 (N(alpha)-acetyltransferase 50, NatE catalytic subunit [Source:MGI Symbol;Acc:MGI:1919367]) HSP 1 Score: 48.521 bits (114), Expect = 5.172e-6 Identity = 28/90 (31.11%), Postives = 51/90 (56.67%), Query Frame = 1 Query: 766 VEPESISEVGFENQI-IAAISFKLRHIDVRKIVHVTMLGVLKEYRSKGIGKHLINLVLD-QKIVGKYDAVVVHADFS---ACDFFKKFGF 1020 +E ++++ + N I + A+ ++ H +K +++ LG L YR GIG ++N VL+ + G +D + +H S A DF++KFGF Sbjct: 40 LEVGELAKLAYFNDIAVGAVCCRVDHSQNQKRLYIMTLGCLAPYRRLGIGTKMLNHVLNICEKDGTFDNIYLHVQISNESAIDFYRKFGF 129
BLAST of N-acetyltransferase domain-containing protein vs. Ensembl Mouse
Match: Naa50 (N(alpha)-acetyltransferase 50, NatE catalytic subunit [Source:MGI Symbol;Acc:MGI:1919367]) HSP 1 Score: 48.1358 bits (113), Expect = 7.693e-6 Identity = 28/90 (31.11%), Postives = 51/90 (56.67%), Query Frame = 1 Query: 766 VEPESISEVGFENQI-IAAISFKLRHIDVRKIVHVTMLGVLKEYRSKGIGKHLINLVLD-QKIVGKYDAVVVHADFS---ACDFFKKFGF 1020 +E ++++ + N I + A+ ++ H +K +++ LG L YR GIG ++N VL+ + G +D + +H S A DF++KFGF Sbjct: 46 LEVGELAKLAYFNDIAVGAVCCRVDHSQNQKRLYIMTLGCLAPYRRLGIGTKMLNHVLNICEKDGTFDNIYLHVQISNESAIDFYRKFGF 135
BLAST of N-acetyltransferase domain-containing protein vs. TrEMBL
Match: A0A2C9JQY1 (N-acetyltransferase domain-containing protein OS=Biomphalaria glabrata OX=6526 GN=106064321 PE=4 SV=1) HSP 1 Score: 185.652 bits (470), Expect = 4.225e-46 Identity = 171/621 (27.54%), Postives = 301/621 (48.47%), Query Frame = 1 Query: 268 DVTNNLKLKDM---EAFVGDTKKSEIIHSTVGLFDICLPDMDINTIYGSVVDKEAYTILVFASQAHALKNIITKVKIMKNKPSKINLIKEFLERKENEQPNITENEDVYSSTEDKE-------------DAFEIIFNDNDEKEDSGAXXXXXXXXXXXXXXXXXXXXXXIKTVYKRKLNHLS----VEPESISEVGFENQIIAAISFKLRHIDVR-KIVHVTMLGVLKEYRSKGIGKHLINLVLDQKIVGKYDAVVVHADFSACDFFKKFGFSDDPILNIQWHTLEPEYTNCSLLTYLPSYSNQDRENKLLAEEFSTAEMEVDIKL--WQKKMTEVHCFQFQTFQRMKMEIQHLKETIKNQDNIMKTIMKELRESNKEKCRLERFLKNXXXXXXXXXXXXXXXXXXXXXXKEENDLLDNVEFKVKSHFFESVKMVGESDFINLLEFI-KSDPQPLLIAEFKAIKRSVNVXXXXXXXXXXXXXXXXYYCESPLMKEKEKLKILTEGFDKNHRKTGSQGLGYYFASNPATAAIYASSNNVIVADVILGNVYRNIGEIQPLKESPPDGYNSILVTS-LYSQQSNNNAAMPDIHLSKDKSSFYTQEFVIFDAAQALPLGLISFST 2055 D L+LK + + + +++H+ GL+DI LPDM+ TIY +V K A TI + A N++ ++ I K + L+++ E+KE N+D + + D+ AF +F+D DE+E ++ + +E+ SS+++Y+ G N +IK+ ++R+ S + P S +G EN+++ ++F+ + I+ + +++H+T++ + YR IG++L++ + I G +DAVVVHAD SA +FF K+GFS D LN +W L +TNC+L+TY P +S + E ++D +L WQ+K E + Q + + EI LK TI+ Q+ ++ ++ R N++ +ER L+++ S + S+ + ++ S F + ++ G + + I K+ P + A ++ R ++ LY+C S L K ILT GF + G G G YF+ P+ AA ++ ++ A V LG ++ + ++SP +GY+SI LY Q N NA + QE+V+FDA Q LPL ++S+S Sbjct: 82 DFNRILQLKQVHENDGIITGVSNRDLLHAVCGLYDISLPDMESETIYNTVCAKWARTIAIVQDIKDATDNMMERL-IKKRVREQKKLLEDQHEKKE-------ANKDAWKAKIDEVEDVFKEEEEEVHLSAFIDVFSDTDEEE---DEDVDEEEEDSSEENYTKGINTFIKSSFERRQQRESSDCLITP---STIGIENRLLGCVTFEKKFIEEKQRVIHITLISIRPRYRHYKIGQYLLSKCVSPVITGHFDAVVVHADNSAVNFFGKYGFSADVALNKKWGELADAFTNCTLMTYFPPFSGHSLLPTKVTREQDADMYDIDQELEKWQRKSEEAYQGQLTCILKFRNEILQLKNTIRVQNELLTKLVTTNR-VNRDALEIERDLRSTHLDQAVSSLTRGLQSLNTESKQPLQSFSSISNTEIISRFIQGMEADGSVKIVYSVTSINKAILSPDVHAMYEKTVRHLH---------DSSMITTLYFCGS-LEKPSRLQHILTHGFSEEDFSYGEFGRGLYFSKYPSKAAQFSVLGKLLEAQVALGQT-ESVLKCDRTRKSPSEGYDSIFTPGRLYRQGDNENAML-------------CQEYVLFDAHQVLPLWILSYSA 663
BLAST of N-acetyltransferase domain-containing protein vs. TrEMBL
Match: K1R104 (N-acetyltransferase domain-containing protein OS=Crassostrea gigas OX=29159 GN=CGI_10025416 PE=4 SV=1) HSP 1 Score: 177.563 bits (449), Expect = 3.072e-43 Identity = 114/349 (32.66%), Postives = 191/349 (54.73%), Query Frame = 1 Query: 304 AFVGDTKKSEIIHSTVGLFDICLPDMDINTIYGSVVDKEAYTILVFASQAHALKNIITKVKIMKNKPSKINLIKEFLERKENEQPNITENEDVYSSTEDKEDAFEIIFNDNDEKEDSGAXXXXXXXXXXXXXXXXXXXXXXIKTVYKRKLNHLSVEPESISEVGFENQIIAAISFKLRHIDVRKIVHVTMLGVLKEYRSKGIGKHLINLVLDQKIVGKYDAVVVHADFSACDFFKKFGFSDDPILNIQWHTLEPEYTNCSLLTYLPSYSNQDRENKLLAEEFSTAEMEVDIKLWQKKMTEVHCFQFQTFQRMKMEIQHLKETIKNQDNIMKTIMKELRESNKEKCRLER 1350 A + +++H+ VGL+D+ L DM + +Y SV DK A TI++ ++++ K K ++ NL K+ + + ++ + + ++ K F +++ E +E+ ++D+S G N++IK +R+ E S VG EN+II AI+F+ ++I +++H+T+L V K YR GIGK+L+ +L+ ++VG YDA+VVHAD A DFF+KFGFSDD +LN +W L ++TNC+L+ YLP++S + L E+E W++K TEV+ Q RMK EI LK + Q+ ++ T++ E KEK +E+ Sbjct: 87 AMIPGISNRDLLHAVVGLYDVSLSDMTPDVLYSSVCDKWARTIVLVRDVQETVEDLT------KRKATRRNLAKKVDDEDQAKEEGEEDKYEEEEASPSK---FATVYS---------DTESEEEEEEDDEEDFSKGINSFIKKAAERRTQQKVTETVSQDMVGIENRIIGAITFEKKYIQKDRVIHLTLLSVRKRYRKFGIGKYLLQQILEPEVVGHYDAIVVHADNGAVDFFQKFGFSDDIVLNSRWSELAEQFTNCTLMAYLPAFSGHTLLSTLKIPGLEVFELEQQFNKWKEKTTEVYQQQVSIVMRMKHEIIELKSMNEKQNELIDTLILENERLKKEKLMIEK 417
BLAST of N-acetyltransferase domain-containing protein vs. TrEMBL
Match: A0A2C9JQZ3 (N-acetyltransferase domain-containing protein OS=Biomphalaria glabrata OX=6526 GN=106064321 PE=4 SV=1) HSP 1 Score: 168.703 bits (426), Expect = 5.067e-41 Identity = 121/429 (28.21%), Postives = 208/429 (48.48%), Query Frame = 1 Query: 784 SEVGFENQIIAAISFKLRHIDVR-KIVHVTMLGVLKEYRSKGIGKHLINLVLDQKIVGKYDAVVVHADFSACDFFKKFGFSDDPILNIQWHTLEPEYTNCSLLTYLPSYSNQDRENKLLAEEFSTAEMEVDIKL--WQKKMTEVHCFQFQTFQRMKMEIQHLKETIKNQDNIMKTIMKELRESNKEKCRLERFLKNXXXXXXXXXXXXXXXXXXXXXXKEENDLLDNVEFKVKSHFFESVKMVGESDFINLLEFI-KSDPQPLLIAEFKAIKRSVNVXXXXXXXXXXXXXXXXYYCESPLMKEKEKLKILTEGFDKNHRKTGSQGLGYYFASNPATAAIYASSNNVIVADVILGNVYRNIGEIQPLKESPPDGYNSILVTS-LYSQQSNNNAAMPDIHLSKDKSSFYTQEFVIFDAAQALPLGLISFST 2055 S +G EN+++ ++F+ + I+ + +++H+T++ + YR IG++L++ + I G +DAVVVHAD SA +FF K+GFS D LN +W L +TNC+L+TY P +S + E ++D +L WQ+K E + Q + + EI LK TI+ Q+ ++ ++ R N++ +ER L+++ S + S+ + ++ S F + ++ G + + I K+ P + A ++ R ++ LY+C S L K ILT GF + G G G YF+ P+ AA ++ ++ A V LG ++ + ++SP +GY+SI LY Q N NA + QE+V+FDA Q LPL ++S+S Sbjct: 139 STIGIENRLLGCVTFEKKFIEEKQRVIHITLISIRPRYRHYKIGQYLLSKCVSPVITGHFDAVVVHADNSAVNFFGKYGFSADVALNKKWGELADAFTNCTLMTYFPPFSGHSLLPTKVTREQDADMYDIDQELEKWQRKSEEAYQGQLTCILKFRNEILQLKNTIRVQNELLTKLVTTNR-VNRDALEIERDLRSTHLDQAVSSLTRGLQSLNTESKQPLQSFSSISNTEIISRFIQGMEADGSVKIVYSVTSINKAILSPDVHAMYEKTVRHLH---------DSSMITTLYFCGS-LEKPSRLQHILTHGFSEEDFSYGEFGRGLYFSKYPSKAAQFSVLGKLLEAQVALGQT-ESVLKCDRTRKSPSEGYDSIFTPGRLYRQGDNENAML-------------CQEYVLFDAHQVLPLWILSYSA 542
BLAST of N-acetyltransferase domain-containing protein vs. TrEMBL
Match: A0A210R5W7 (N-acetyltransferase domain-containing protein OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT08300 PE=4 SV=1) HSP 1 Score: 169.088 bits (427), Expect = 2.912e-40 Identity = 111/344 (32.27%), Postives = 194/344 (56.40%), Query Frame = 1 Query: 328 SEIIHSTVGLFDICLPDMDINTIYGSVVDKEAYTILVFASQAHALKNIITKVKIMKNKPSKINLIKEFLERKENEQPNITENEDVYSSTEDKEDAFEIIFNDNDEKEDSGAXXXXXXXXXXXXXXXXXXXXXXIKTVYKRKLNHLSVEPESISE--VGFENQIIAAISFKLRHIDVR-KIVHVTMLGVLKEYRSKGIGKHLINLVLDQKIVGKYDAVVVHADFSACDFFKKFGFSDDPILNIQWHTLEPEYTNCSLLTYLPSYSNQDRENKLLAEEFSTAEMEVDIKLWQKKMTEVHCFQFQTFQRMKMEIQHLKETIKNQDNIMKTIMKELRESNKEKCRLER 1350 ++++H+ VGL+D+ L +M + +Y +V +K A TI++ ++++ K KI K + E E K E+ EN+D+Y E F +++D + +E+ D+ + ++ S + + KTV +RK +P I E VG EN+II ++F+ +++ + ++VH+T+L V + +R GIGK+L+ V+D +VG +DA+VVHAD +A +FF+ FGFSDD +LN +W L ++TNC+L+ YLP +S + + F E+E + W++K EV+ Q RMK EI LK Q+ +++T++K+ + KEK +E+ Sbjct: 95 TDLLHAVVGLYDVSLSEMTPDVLYATVCEKWARTIVLVRDLKETVRSLEEK-KIQKTSDKDDDNETESKETKTKEEKEDGENDDIYEEEEQLTSKFADVYSDTESEEEDLEDDDDEEDFSKGINTFIK------KTVERRKKRQ--CKPREIKEEQVGIENRIIGCVTFEKKYVRQKDRVVHLTLLSVRRRHRKFGIGKYLLQQVIDPAVVGHFDAIVVHADNAAVEFFQHFGFSDDVVLNSRWSELAEQFTNCTLMCYLPGFSGHSLLSTVKVPGFEVFELEQEFNKWKEKTVEVYQNQVSVVMRMKHEILQLKALTHKQNTLIETLLKDNEKLRKEKYAVEK 429 HSP 2 Score: 64.6994 bits (156), Expect = 5.718e-7 Identity = 39/134 (29.10%), Postives = 70/134 (52.24%), Query Frame = 1 Query: 1651 YYCESPLMKEKEKLK-ILTEGFDKNHRKTGSQGLGYYFASNPATAAIYASSNNVIVADVILGNVYRNIGEIQPLKESPPDGYNSILVTSLYSQQSNNNAAMPDIHLSKDKSSFYTQEFVIFDAAQALPLGLISF 2049 YYC + ++ E++ ILT GF ++ G G G YF+ P+ AA ++ +++ + LG++ +I + ++SP G++SI+ + + S TQE+V+FDA Q +PLGLI++ Sbjct: 584 YYCGT--LEHPERIPDILTHGFTESDFIHGEYGRGLYFSKYPSKAAHFSGVRKILLVEAGLGHI-ESITKQDRARKSPHPGHDSIITPGRLKPSRDCGL----------EESTMTQEYVVFDAKQVMPLGLITY 704
BLAST of N-acetyltransferase domain-containing protein vs. TrEMBL
Match: V4AGM8 (N-acetyltransferase domain-containing protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_233022 PE=4 SV=1) HSP 1 Score: 167.933 bits (424), Expect = 6.583e-40 Identity = 121/382 (31.68%), Postives = 215/382 (56.28%), Query Frame = 1 Query: 241 MVHLYSIFKDVTNNLKLKDMEAF-----VGDTKKSEIIHSTVGLFDICLPDMDINTIYGSVVDKEAYTILVFASQAHALKNIITKVKIMKNKPSKINLIKEFLER--KENEQPNITENEDVYSSTEDKEDAFEIIFNDNDEKEDSGAXXXXXXXXXXXXXXXXXXXXXXIKTVYKRKLNHLSVEPESISE--VGFENQIIAAISFKLRHIDVR-KIVHVTMLGVLKEYRSKGIGKHLINLVLDQKIVGKYDAVVVHADFSACDFFKKFGFSDDPILNIQWHTLEPEYTNCSLLTYLPSYSNQDRENKLLAEEFSTAEMEVDIKLWQKKMTEVHCFQFQTFQRMKMEIQHLKETIKNQDNIMKTIMKELRESNKEKCRLERFL 1356 +V Y + D L+L + + + ++H+ VGL+DI L +M ++ +Y +V +K A TI++ A+K+ + K K ++N E + K +E+ N+ +D Y E FE +F+ + ED D+ E +ED S ++D+S G +++IK+ R+ +V+ S+ E +G E++II ++F+ +++ + ++VH+T++ V YR GIGK+L++ V+D + G+Y+A+VVHAD A +FF+KFGFSDD +LN +W L ++TNC+L+ YLP ++ + + EM+ ++K W+ K E + Q RMK EI +L++ +K QDN++K + E + +EK LE+ L Sbjct: 59 VVSAYPVIVDFRRLLQLHNTNPYHNNDVISGISNDNLLHAVVGLYDIALSEMTLDVLYATVCEKWARTIVLVQDMKDAVKDAEFR---KKEKKEQMNGKSESDDESNKLDEKLNVDIGDDKYEEEEGSPSKFEGVFS---DVEDDEEDDDEEEEDESDEEDFSVGIHSFIKSAVTRR-KQRNVKETSLDEHDIGVESRIIGCLTFEKKYVRHKERVVHLTIVTVRPRYRKYGIGKYLLSQVIDSSVSGQYEAIVVHADNGAVEFFQKFGFSDDVVLNSRWSELAEQFTNCTLMCYLPGFTGHTVLSAINLPGLEVYEMDQELKKWKDKTLESYQAQITCVMRMKQEIFNLQKKVKCQDNMIKMLAVENEKVKQEKIILEKEL 433
BLAST of N-acetyltransferase domain-containing protein vs. Ensembl Cavefish
Match: naa50 (N(alpha)-acetyltransferase 50, NatE catalytic subunit [Source:NCBI gene;Acc:103040640]) HSP 1 Score: 47.7506 bits (112), Expect = 7.590e-6 Identity = 28/90 (31.11%), Postives = 51/90 (56.67%), Query Frame = 1 Query: 766 VEPESISEVGFENQI-IAAISFKLRHIDVRKIVHVTMLGVLKEYRSKGIGKHLINLVLD-QKIVGKYDAVVVHADFS---ACDFFKKFGF 1020 +E ++++ + N I + A+ ++ H +K +++ LG L YR GIG ++N VL+ + G +D + +H S A DF++KFGF Sbjct: 40 LEVGELAKLAYFNDIAVGAVCCRVDHSQNQKRLYIMTLGCLAPYRRLGIGTKMLNHVLNICEKDGTFDNIYLHVQISNESAIDFYQKFGF 129
BLAST of N-acetyltransferase domain-containing protein vs. Ensembl Medaka
Match: naa50 (N(alpha)-acetyltransferase 50, NatE catalytic subunit [Source:NCBI gene;Acc:101162486]) HSP 1 Score: 47.7506 bits (112), Expect = 6.544e-6 Identity = 28/90 (31.11%), Postives = 51/90 (56.67%), Query Frame = 1 Query: 766 VEPESISEVGFENQI-IAAISFKLRHIDVRKIVHVTMLGVLKEYRSKGIGKHLINLVLD-QKIVGKYDAVVVHADFS---ACDFFKKFGF 1020 +E ++++ + N I + A+ ++ H +K +++ LG L YR GIG ++N VL+ + G +D + +H S A DF++KFGF Sbjct: 40 LEVGELAKLAYFNDIAVGAVCCRVDHSQNQKRLYIMTLGCLAPYRRLGIGTKMLNHVLNICEKDGTFDNIYLHVQISNESAIDFYQKFGF 129
BLAST of N-acetyltransferase domain-containing protein vs. Planmine SMEST
Match: SMESG000023874.1 (SMESG000023874.1) HSP 1 Score: 1180.24 bits (3052), Expect = 0.000e+0 Identity = 647/651 (99.39%), Postives = 650/651 (99.85%), Query Frame = 1 Query: 115 MSYKIIDVNNPVLLLKTHEVICKNRRNKKENSSSCDEILNLWMVHLYSIFKDVTNNLKLKDMEAFVGDTKKSEIIHSTVGLFDICLPDMDINTIYGSVVDKEAYTILVFASQAHALKNIITKVKIMKNKPSKINLIKEFLERKENEQPNITENEDVYSSTEDKEDAFEIIFNDNDEKEDSGAXXXXXXXXXXXXXXXXXXXXXXIKTVYKRKLNHLSVEPESISEVGFENQIIAAISFKLRHIDVRKIVHVTMLGVLKEYRSKGIGKHLINLVLDQKIVGKYDAVVVHADFSACDFFKKFGFSDDPILNIQWHTLEPEYTNCSLLTYLPSYSNQDRENKLLAEEFSTAEMEVDIKLWQKKMTEVHCFQFQTFQRMKMEIQHLKETIKNQDNIMKTIMKELRESNKEKCRLERFLKNXXXXXXXXXXXXXXXXXXXXXXKEENDLLDNVEFKVKSHFFESVKMVGESDFINLLEFIKSDPQPLLIAEFKAIKRSVNVXXXXXXXXXXXXXXXXYYCESPLMKEKEKLKILTEGFDKNHRKTGSQGLGYYFASNPATAAIYASSNNVIVADVILGNVYRNIGEIQPLKESPPDGYNSILVTSLYSQQSNNNAAMPDIHLSKDKSSFYTQEFVIFDAAQALPLGLISFSTTDSQ 2067 MSYKIIDVNNPVLLLKTHEVICKNRRNKKENSSSCDEILNLWMVHLYSIFKDVTNNLKLKDMEAFVGDTKKSEIIHSTVGLFDICLPDMDINTIYGSVVDKEAYTILVFASQA+ALKNIITKVKIMKNKPSKI+LIKEFLERKENE+PNITENEDVYSSTEDKEDAFEIIFNDNDEKEDSGADNKENDEDSSSDDDYSYGYNNYIKTVYKRKLNHLSVEPESISEVGFENQIIAAISFKLRHIDVRKIVHVTMLGVLKEYRSKGIGKHLINLVLDQKIVGKYDAVVVHADFSACDFFKKFGFSDDPILNIQWHTLEPEYTNCSLLTYLPSYSNQDRENKLLAEEFSTAEMEVDIKLWQKKMTEVHCFQFQTFQRMKMEIQHLKETIKNQDNIMKTIMKELRESNKEKCRLERFLKNSASSSINVSSVEPVSSIIDSISKEENDLLDNVEFKVKSHFFESVKMVGESDFINLLEFIKSDPQPLLIAEFKAIKRSVNVLSPRLSSKLLISSRILYYCESPLMKEKEKLKILTEGFDKNHRKTGSQGLGYYFASNPATAAIYASSNNVIVADVILGNVYRNIGE QPLKESPPDGYNSILVTSLYSQQSNNNAAMPDIHLSKDKSSFYTQEFVIFDAAQALPLGLISFSTTDSQ Sbjct: 1 MSYKIIDVNNPVLLLKTHEVICKNRRNKKENSSSCDEILNLWMVHLYSIFKDVTNNLKLKDMEAFVGDTKKSEIIHSTVGLFDICLPDMDINTIYGSVVDKEAYTILVFASQANALKNIITKVKIMKNKPSKISLIKEFLERKENEEPNITENEDVYSSTEDKEDAFEIIFNDNDEKEDSGADNKENDEDSSSDDDYSYGYNNYIKTVYKRKLNHLSVEPESISEVGFENQIIAAISFKLRHIDVRKIVHVTMLGVLKEYRSKGIGKHLINLVLDQKIVGKYDAVVVHADFSACDFFKKFGFSDDPILNIQWHTLEPEYTNCSLLTYLPSYSNQDRENKLLAEEFSTAEMEVDIKLWQKKMTEVHCFQFQTFQRMKMEIQHLKETIKNQDNIMKTIMKELRESNKEKCRLERFLKNSASSSINVSSVEPVSSIIDSISKEENDLLDNVEFKVKSHFFESVKMVGESDFINLLEFIKSDPQPLLIAEFKAIKRSVNVLSPRLSSKLLISSRILYYCESPLMKEKEKLKILTEGFDKNHRKTGSQGLGYYFASNPATAAIYASSNNVIVADVILGNVYRNIGETQPLKESPPDGYNSILVTSLYSQQSNNNAAMPDIHLSKDKSSFYTQEFVIFDAAQALPLGLISFSTTDSQ 651 The following BLAST results are available for this feature:
BLAST of N-acetyltransferase domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 2
BLAST of N-acetyltransferase domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 0
BLAST of N-acetyltransferase domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 0
BLAST of N-acetyltransferase domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of N-acetyltransferase domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 2
BLAST of N-acetyltransferase domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 3
BLAST of N-acetyltransferase domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 0
BLAST of N-acetyltransferase domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of N-acetyltransferase domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 1
BLAST of N-acetyltransferase domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 0
BLAST of N-acetyltransferase domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of N-acetyltransferase domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 0
BLAST of N-acetyltransferase domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 1
BLAST of N-acetyltransferase domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 1
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30019398 ID=SMED30019398|Name=N-acetyltransferase domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=2186bpback to top protein sequence of SMED30019398-orf-1 >SMED30019398-orf-1 ID=SMED30019398-orf-1|Name=SMED30019398-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=652bp MSYKIIDVNNPVLLLKTHEVICKNRRNKKENSSSCDEILNLWMVHLYSIFback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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