SMED30019358

Overview
NameSMED30019358
Smed IDSMED30019358
Length (bp)4743
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of SMED30019358 (SMED30019358) t-SNE clustered cells

Violin plots show distribution of expression levels for SMED30019358 (SMED30019358) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of SMED30019358 (SMED30019358) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for SMED30019358 (SMED30019358) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30019358

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 5

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
head regionSMED30019358SMESG000017193.1 SmedASXL_015745SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
nervous systemSMED30019358SMESG000017193.1 dd_Smed_v4_13200_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30019358SMESG000017193.1 dd_Smed_v6_13200_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
photoreceptor neuronSMED30019358SMESG000017193.1 SMED30019358smed_20140614PMID:22884275
Lapan et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
head regionSMED30019358SMESG000017193.1 OX_Smed_1.0.07211ox_Smed_v2PMID:24238224
Kao et al., 2013		whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of SMED30019358 vs. TrEMBL
Match: A0A5K4F164 (Uncharacterized protein OS=Schistosoma mansoni OX=6183 PE=4 SV=1)

HSP 1 Score: 109.383 bits (272), Expect = 5.895e-20
Identity = 108/463 (23.33%), Postives = 188/463 (40.60%), Query Frame = 3 
Query:  579 INERLSISVYQESTFNSTK---SRCTQRWPTVMVIIMDNRISQLPSCERVK-------FWHLLN-KYLPKHDSHLTFEED---IPSLLKS-------LSVLSQWSLKGSKRPSPF---QSAIVYQIGCGSIPESVINKFKYFEKE--------------DNINHLSKVLSLPIRGWLIADQIYPATIRKRRHRRNSYLKFTEYSSIFYQQEKQRKEDWKEAQIVVEGSGQ--FDENWTVPNVDLSRLPIAVSNKTKNETIPYVRKPEKSQPIIRKSLTNFTVLIGSRKY----FQIPPKTFFDAEDGYNQQLKIKAFIRSKES--------------QIDRQISFNPTQWIYFLEKQQAIGLQPRKTDVGSYYITICAYDTDRNRVCDGARLFIKKPKTINRKSYIAAPPGVVWKYPIQATWPDEVKYSNNDSIVIKVQSSSLIEWQGNISRLSLVTEAYTSK 1793
            IN + SI  +     N  K    +C ++ PT+++ I + +I  L   ER++       F +L+N  YL +       E+D   +  +L+S       LS+L+        R S     Q   +  IGCG IP+ ++      EK                N     K   + +  W++ D I+ +     + ++N+  +            K+     +EA  + EGSG   F +    P +D        S    +  IP V+              N+   I +  Y     QIP  TF+D +DGY Q LK+  +  + E+               I  +I+ +  +W+ F  K Q I L+P    VG++   +CA D D+NRVC+  ++ +K+P    +   +  PPG+ W Y I   W  E+K  + D + ++V+  S   W      + +++    S+
Sbjct:  107 INSKNSIQSFHHILLNYNKYLSKKCYKQVPTLLLFIFNVQICNLSYIERIELNKIIKLFMNLINITYLNQSLIISNIEDDNDNVNLILESPTIYERKLSILASAKAHNYIRNSKSNFSQLVSIQHIGCGIIPDYILKILTILEKRFQMGLIPIWTLLNNTNFTRFEKFKHITLAEWIVGDLIHNSLHDAAQTKQNNVKR---------SLNKRSALSSREAGYLEEGSGMASFQQ---FPKIDYRSFLEHSSTDLIHSNIPRVK--------------NYITPIKTTVYQISNIQIPQNTFYDLQDGYTQNLKLTLYASNLENISYIELKSMENLNQAIGEEITRDIKKWVSFDTKNQIIRLKPLPDHVGNHTFIVCATDRDQNRVCEPFQIIVKRPSPFRKNFILRIPPGIFWCYQIPIYWFKELKTLSFDKLDLEVKGDSPFSWNVQTGEVCVISNLKISQ 543
[Close]
BLAST of SMED30019358 vs. TrEMBL
Match: A0A183MQ49 (Uncharacterized protein OS=Schistosoma margrebowiei OX=48269 GN=SMRZ_LOCUS18174 PE=4 SV=1)

HSP 1 Score: 107.457 bits (267), Expect = 1.059e-19
Identity = 103/404 (25.50%), Postives = 170/404 (42.08%), Query Frame = 3 
Query:  732 LLNKYLPKHDSHLTFEEDIPSLLKSLSVLSQWSLKGSKRP--------SPFQSAIVYQ-IGCGSIPESVINKFKYFEKE------------DNIN--HLSKVLSLPIRGWLIADQIY----PATIRKRRHRRNSYLKFTEYSSIFYQQEKQRKEDWKEAQIVVEGSG-----QFDENWTVPNVDLSRLPIAVSNKTKNETIPYVRKPEKSQPIIRKSLTNFTVLIGSRKY----FQIPPKTFFDAEDGYNQQLKIKAFIRSKES--------------QIDRQISFNPTQWIYFLEKQQAIGLQPRKTDVGSYYITICAYDTDRNRVCDGARLFIKKPKTINRKSYIAAPPGVVWKYPIQATWPDEVKYSNNDSIVIKVQSSSLIEWQGNISRLSLVTEAYTSK 1793
            L+N+ + +  ++  F+  I SL  S  V  + S+  S +         S F   I  Q IGCG IP+ ++      EK+            DN N     K  ++ +  W++ D I+     AT  K+ + + S  K +  SS              EA  + EGSG     QF +      +D S   +  SN      IP V+              N+   I +  Y     QIP  TF+D +DGY Q LK+  +  ++E+               I  +I+ +  +W+ F  K Q I L+P    VG++   +CA D D+NRVC+  ++ +K+P    +   +  PPGV+W Y I   W  E+K  + D + ++V+  S   W      + +++    S+
Sbjct:   18 LINQIITETMTNAQFQLTIHSLKCSCPVYRKLSILASAKARNSIGNSKSNFSQLISIQHIGCGIIPDYILKMLTVLEKKFQMGLIPVWTLLDNTNFTRFEKFKNITLAEWIVGDLIHNSLDDATQTKQENVKRSLNKRSAVSS-------------HEAGYLEEGSGMASFQQFSKMDYRSFLDHSSSDLIHSN------IPRVK--------------NYITPIKTTVYQISNIQIPQNTFYDLQDGYTQNLKLTLYASNRENISYIELKSMENLNQAIGEEITRDIKKWVSFDPKNQIIRLKPLPEHVGNHTFIVCATDRDQNRVCEPFQIIVKRPSPFRKNFILRIPPGVLWCYQIPIYWFKELKTLSFDKLDLEVKGDSPFSWNVQTGEVCVISNLKISQ 388
[Close]
BLAST of SMED30019358 vs. TrEMBL
Match: A0A4Z2CPA3 (Dystroglycan isoform 1 OS=Schistosoma japonicum OX=6182 GN=EWB00_008692 PE=4 SV=1)

HSP 1 Score: 103.219 bits (256), Expect = 3.102e-18
Identity = 100/447 (22.37%), Postives = 182/447 (40.72%), Query Frame = 3 
Query:  630 TKSRCTQRWPTVMVIIMDNRISQLPSCERVKFWHLLNKYLP--------------------KHDSHLTFEEDIPSLL-KSLSVLSQWSLKGSKRPSP--FQSAIVYQ-IGCGSIPESVINKFKYFEKE--------------DNINHLSKVLSLPIRGWLIADQIYPA---TIRKRRHRRNSYLKFTEYSSIFYQQEKQRKEDWKEAQIVVEGSGQFDENWTVPNVDLSRLPIAVSNKTKNETIPYVRKPEKSQPIIRKSLTNFTVLIGSRKY----FQIPPKTFFDAEDGYNQQLKIKAF-----------IRSKESQID---RQISFNPTQWIYFLEKQQAIGLQPRKTDVGSYYITICAYDTDRNRVCDGARLFIKKPKTINRKSYIAAPPGVVWKYPIQATWPDEVKYSNNDSIVIKVQSSSLIEWQGNISRLSLVTEAYTSK 1793
            T  +C ++ PT+++ I + ++      ER+   +++N ++                      +D +L  E   PS+  K LS+L+        R S   +   I  Q IGCG IP++ +      EK+               N  H  K+  + +  W++ D I+ +   TI+              + ++     K+     + A  + EGSG    +   P +D        S    +  IP V+              N+   I +  Y     QIP  TF+D +DGY Q LK+  +           ++SKE+ I     +I+ +  +W+ F  K Q + L+P    VG++   +CA D D+NR C+  ++ +K+P    +   +   PGV W Y I   W  E+K  + D + ++V+  S   W  +   + +++    S+
Sbjct:  156 TLRKCFKQAPTILLFIFNVQLCHFNYYERILLKNMINLFMNFTNFVYFNYSFIKLNIENDNYNDVNLIMES--PSVYEKKLSILANAKAHNYNRNSQANYSHLISLQHIGCGVIPDNTLKMLTVLEKKLRIGLVPVWTLLNGINFTHYQKLKHIKLAEWIVGDLIHNSLHDTIQ------------INHENVKRSVSKRSAMSSRVAGYLEEGSGMASFH-QFPKMDYRSFMEHSSPDQTHSNIPRVK--------------NYITPIKTTVYQISNVQIPQNTFYDLQDGYTQNLKLSLYASNSENISYIELKSKENLIQALGEEITRDIKKWVSFDAKNQILRLKPLPDHVGNHTFIVCATDRDQNRACEPFQIIVKRPSPFRKNFILRISPGVFWCYQIPIYWFKELKTVSFDKLDLEVKGDSPFSWNVHTGEVCVISSLKISQ 573
[Close]
BLAST of SMED30019358 vs. TrEMBL
Match: A0A4Z2CP11 (Dystroglycan isoform 2 OS=Schistosoma japonicum OX=6182 GN=EWB00_008692 PE=4 SV=1)

HSP 1 Score: 102.064 bits (253), Expect = 1.143e-17
Identity = 100/447 (22.37%), Postives = 182/447 (40.72%), Query Frame = 3 
Query:  630 TKSRCTQRWPTVMVIIMDNRISQLPSCERVKFWHLLNKYLP--------------------KHDSHLTFEEDIPSLL-KSLSVLSQWSLKGSKRPSP--FQSAIVYQ-IGCGSIPESVINKFKYFEKE--------------DNINHLSKVLSLPIRGWLIADQIYPA---TIRKRRHRRNSYLKFTEYSSIFYQQEKQRKEDWKEAQIVVEGSGQFDENWTVPNVDLSRLPIAVSNKTKNETIPYVRKPEKSQPIIRKSLTNFTVLIGSRKY----FQIPPKTFFDAEDGYNQQLKIKAF-----------IRSKESQID---RQISFNPTQWIYFLEKQQAIGLQPRKTDVGSYYITICAYDTDRNRVCDGARLFIKKPKTINRKSYIAAPPGVVWKYPIQATWPDEVKYSNNDSIVIKVQSSSLIEWQGNISRLSLVTEAYTSK 1793
            T  +C ++ PT+++ I + ++      ER+   +++N ++                      +D +L  E   PS+  K LS+L+        R S   +   I  Q IGCG IP++ +      EK+               N  H  K+  + +  W++ D I+ +   TI+              + ++     K+     + A  + EGSG    +   P +D        S    +  IP V+              N+   I +  Y     QIP  TF+D +DGY Q LK+  +           ++SKE+ I     +I+ +  +W+ F  K Q + L+P    VG++   +CA D D+NR C+  ++ +K+P    +   +   PGV W Y I   W  E+K  + D + ++V+  S   W  +   + +++    S+
Sbjct:  156 TLRKCFKQAPTILLFIFNVQLCHFNYYERILLKNMINLFMNFTNFVYFNYSFIKLNIENDNYNDVNLIMES--PSVYEKKLSILANAKAHNYNRNSQANYSHLISLQHIGCGVIPDNTLKMLTVLEKKLRIGLVPVWTLLNGINFTHYQKLKHIKLAEWIVGDLIHNSLHDTIQ------------INHENVKRSVSKRSAMSSRVAGYLEEGSGMASFH-QFPKMDYRSFMEHSSPDQTHSNIPRVK--------------NYITPIKTTVYQISNVQIPQNTFYDLQDGYTQNLKLSLYASNSENISYIELKSKENLIQALGEEITRDIKKWVSFDAKNQILRLKPLPDHVGNHTFIVCATDRDQNRACEPFQIIVKRPSPFRKNFILRISPGVFWCYQIPIYWFKELKTVSFDKLDLEVKGDSPFSWNVHTGEVCVISSLKISQ 573
[Close]
BLAST of SMED30019358 vs. TrEMBL
Match: A0A095AGE4 (Dystroglycan OS=Schistosoma haematobium OX=6185 GN=MS3_01122 PE=4 SV=1)

HSP 1 Score: 91.6633 bits (226), Expect = 6.340e-15
Identity = 48/169 (28.40%), Postives = 81/169 (47.93%), Query Frame = 3 
Query: 1329 QIPPKTFFDAEDGYNQQLKIKAFIRSKES--------------QIDRQISFNPTQWIYFLEKQQAIGLQPRKTDVGSYYITICAYDTDRNRVCDGARLFIKKPKTINRKSYIAAPPGVVWKYPIQATWPDEVKYSNNDSIVIKVQSSSLIEWQGNISRLSLVTEAYTSK 1793
            QIP  TF+D +DGY Q LK+  +  + E+               I  +I+ +   W+ F  K Q I L+P    VG++   +CA D D+NR C+  ++ +K+P    +   +  PPGV W Y I   W  E+K  + D + ++V+  S   W      + +++    S+
Sbjct:  103 QIPQNTFYDLQDGYTQNLKLTLYASNSENISYIELKSMENLNQAIGEEITRDIKNWVSFDPKNQIIRLKPLPDHVGNHTFIVCATDRDQNRACEPFQIIVKRPSPFRKNFILRIPPGVFWCYQIPIYWFKELKTLSFDKLDLEVKGDSPFSWNVQTGEVCVISNLKISQ 271
[Close]
BLAST of SMED30019358 vs. Planmine SMEST
Match: SMESG000017193.1 (SMESG000017193.1)

HSP 1 Score: 2721.42 bits (7053), Expect = 0.000e+0
Identity = 1375/1381 (99.57%), Postives = 1378/1381 (99.78%), Query Frame = 3 
Query:  423 AATLNAVVGKLFHINQSLIVQSGARPNIPNWLCGSPGKYQGIPLKGNIGEYRINERLSISVYQESTFNSTKSRCTQRWPTVMVIIMDNRISQLPSCERVKFWHLLNKYLPKHDSHLTFEEDIPSLLKSLSVLSQWSLKGSKRPSPFQSAIVYQIGCGSIPESVINKFKYFEKEDNINHLSKVLSLPIRGWLIADQIYPATIRKRRHRRNSYLKFTEYSSIFYQQEKQRKEDWKEAQIVVEGSGQFDENWTVPNVDLSRLPIAVSNKTKNETIPYVRKPEKSQPIIRKSLTNFTVLIGSRKYFQIPPKTFFDAEDGYNQQLKIKAFIRSKESQIDRQISFNPTQWIYFLEKQQAIGLQPRKTDVGSYYITICAYDTDRNRVCDGARLFIKKPKTINRKSYIAAPPGVVWKYPIQATWPDEVKYSNNDSIVIKVQSSSLIEWQGNISRLSLVTEAYTSKEHQIKMVAESQTTGQTLIWKMIVTSVGLNSYVDATSPELVIKLSSFHTNRIPFELINLIKEKLIGSISRYWTILKSSSREIFLYKIVKGKESFLENSKEAMSILSFVYSPLQSNPVNCSEVSFSSELVDSMKYDLRIASNNWNIELIDIIEIPGKCSNYEAFNPIPYQTTSKPNLISQDHQINAVPDLVNKSINLEVRNGLTFKKIILLPFQNGYAEVLMMELLDINNLVIDESPWVSLLISPYAIYGLPLAENVRSQPYKFKLKVTLRSGSXXXXXXXXXXXRFELQTDHRFGLIISISEKDTLEFDRARQRFNGNPLKTMNQLLVSQTLSYRWQVVETIARYLHTDQCLLDCGTHIYIHSFSEPKSWQVNISWSMLFDSPDSSDYSTTACSHEXXXXXXXXXXXSDQYTESIISMFLSSIYTFDAYPHQTLVRSLQKNSLGTPTWLTVDPLGSCSNSADKTEINSSEAVFWSNISLNQGNIFAVLLDKKLRINKPKAIYQSKIQFSNGSVWDLGWLKLSHDGRIIYGLPLLSDLVLQSYFSLRIFLDSEEVRENLKYYLSMTVKPSRHSTASTHIVNLTILPLQNYAKNVFELDSKIKLARTINAYLHPSCSLGNRTVYNGFRMFKLEPHKRKHLEFCEKAEDVIIHSIRKRSHDKKVFVDIIWSQVSVWSTENGSDSVCNTNSLNDLSGNLFQNFSTQEINQELVSYFENSGIGQILQTQLILFDQCLKAVKRFNLDIPYSPVPKDYQIKPLTTTQASTKXXXXXXXXXXXXXXXXXXXXXXXKRGIPTTFTQLTEKTNKSMALEDFNKSPINSPVSSFIKKPKNNPTLDGFGPSLSNNSPKTPLLSQFSRDDSKSERQKEPAFNDEEAIGSYSYAARHPKSPEPEVASNNSIGISKQPATSNVIRNPAMMMGSRLNPYRN 4565
            AATLNAVVGKLFHINQSLIVQSGARPNIPNWLCGSPGKYQGIPLKGNIGEYRINERLSISVYQESTFNSTKSRCTQRWPTVMVIIMDNRISQLPSCERVKFWHLLNKYLPKHDSHLTFEEDIPSLLKSLSVLSQWSLKGSKRPSP QSAIVYQIGCGSIPESVINKFKYFEKEDNINHLSKVLSLPIRGWLIADQIYPATIRKRRHRRNSYLKFTEYSSIFYQQEKQRKEDWKEAQIVVEGSGQFDENWTVPNVDLSRLPIAVSNKTKNETIPYVRKPEKSQPIIRKSLTNFTVLIGSRKYFQIPPKTFFDAEDGYNQQLKIKAFIRSKESQIDRQISFNPTQWIYFLEKQQAIGLQPRKTDVGSYYITICAYDTDRNRVCDGARLFIKKPKTINRKSYIAAPPGVVWKYPIQATWPDEVKYSNNDSIVIKVQSSSLIEWQGNISRLSLVTEAYTSKEHQIKMVAESQTTGQTLIWKMIVTSVGLNSYVDATSPELVIKLSSFHTNRIPFELINLIKEKLIGSISRYWTILKSSSREIFLYKIVKGKESFLENSKEAMSILSFVYSPLQSNPVNCSEVSFSSELVDSMKYDLRIASNNWNIELIDIIEIPGKCSNYEAFNPIPYQTTSKPNLISQDHQINAVPDLVNKSINLEVRNGLTFKKIILLPFQNGYAEVLMMELLDINNLVIDESPWVSLLISPYAIYGLPLAENVRSQPYKFKLKVTLRSGSVQEVIVNIVVVRFELQTDHRFGLIISISEKDTLEFDRARQRFNG+PLKTMNQLLVSQTLSYRWQVVETIARYLHTDQCLLDCGTHIYIHSFSEPKSWQVNISWSMLFDSPDSSDYSTTACSHEKLKKLIRLLIKSDQYTESIISMFLSSIYTFDAYPHQTLVRSLQKNSLGTPTWLTVDPLGSCSNSADKTEINSSEAVFWSNISLNQGNIFAVLLDKKLRINKPKAIYQSKIQFSNGSVWDLGWLKLSHDGRIIYGLPLLSDLVLQSYFSLRIFLDSEEVRENLKYYLSMT+KPSRHSTASTHIVNLTILPLQNYAKNVFELDSKIKLARTINAYLHPSCSLGNRTVYNGFRMFKLEPHKRKHL+FCEKAEDVIIHSIRKRSHDKKVFVDIIWSQVSVWSTENGSDSVCNTNSLNDLSGNLFQNFSTQEINQELVSYFENSGIGQILQTQLILFDQCLKAVKRFNLDIPYSPVPKDYQIKPLTTTQASTKIVVGVLFFILIFISSICII YFVKRGIP TFTQLTEKTNKSMALEDFNKSPINSPVSSFIKKPKNNPTLDGFGPSLSNNSPKTPLLSQFSRDDSKSERQKEPAFNDEEAIGSYSYAARHPKSPEPEVASNNSIGISKQPATSNVIRNPAMMMGSRLNPYRN
Sbjct:   20 AATLNAVVGKLFHINQSLIVQSGARPNIPNWLCGSPGKYQGIPLKGNIGEYRINERLSISVYQESTFNSTKSRCTQRWPTVMVIIMDNRISQLPSCERVKFWHLLNKYLPKHDSHLTFEEDIPSLLKSLSVLSQWSLKGSKRPSPSQSAIVYQIGCGSIPESVINKFKYFEKEDNINHLSKVLSLPIRGWLIADQIYPATIRKRRHRRNSYLKFTEYSSIFYQQEKQRKEDWKEAQIVVEGSGQFDENWTVPNVDLSRLPIAVSNKTKNETIPYVRKPEKSQPIIRKSLTNFTVLIGSRKYFQIPPKTFFDAEDGYNQQLKIKAFIRSKESQIDRQISFNPTQWIYFLEKQQAIGLQPRKTDVGSYYITICAYDTDRNRVCDGARLFIKKPKTINRKSYIAAPPGVVWKYPIQATWPDEVKYSNNDSIVIKVQSSSLIEWQGNISRLSLVTEAYTSKEHQIKMVAESQTTGQTLIWKMIVTSVGLNSYVDATSPELVIKLSSFHTNRIPFELINLIKEKLIGSISRYWTILKSSSREIFLYKIVKGKESFLENSKEAMSILSFVYSPLQSNPVNCSEVSFSSELVDSMKYDLRIASNNWNIELIDIIEIPGKCSNYEAFNPIPYQTTSKPNLISQDHQINAVPDLVNKSINLEVRNGLTFKKIILLPFQNGYAEVLMMELLDINNLVIDESPWVSLLISPYAIYGLPLAENVRSQPYKFKLKVTLRSGSVQEVIVNIVVVRFELQTDHRFGLIISISEKDTLEFDRARQRFNGSPLKTMNQLLVSQTLSYRWQVVETIARYLHTDQCLLDCGTHIYIHSFSEPKSWQVNISWSMLFDSPDSSDYSTTACSHEKLKKLIRLLIKSDQYTESIISMFLSSIYTFDAYPHQTLVRSLQKNSLGTPTWLTVDPLGSCSNSADKTEINSSEAVFWSNISLNQGNIFAVLLDKKLRINKPKAIYQSKIQFSNGSVWDLGWLKLSHDGRIIYGLPLLSDLVLQSYFSLRIFLDSEEVRENLKYYLSMTLKPSRHSTASTHIVNLTILPLQNYAKNVFELDSKIKLARTINAYLHPSCSLGNRTVYNGFRMFKLEPHKRKHLQFCEKAEDVIIHSIRKRSHDKKVFVDIIWSQVSVWSTENGSDSVCNTNSLNDLSGNLFQNFSTQEINQELVSYFENSGIGQILQTQLILFDQCLKAVKRFNLDIPYSPVPKDYQIKPLTTTQASTKIVVGVLFFILIFISSICIIIYFVKRGIPATFTQLTEKTNKSMALEDFNKSPINSPVSSFIKKPKNNPTLDGFGPSLSNNSPKTPLLSQFSRDDSKSERQKEPAFNDEEAIGSYSYAARHPKSPEPEVASNNSIGISKQPATSNVIRNPAMMMGSRLNPYRN 1400
[Close]
BLAST of SMED30019358 vs. Planmine SMEST
Match: SMESG000020071.1 (SMESG000020071.1)

HSP 1 Score: 229.565 bits (584), Expect = 1.759e-60
Identity = 284/1218 (23.32%), Postives = 519/1218 (42.61%), Query Frame = 3 
Query:  432 LNAVVGKLFHINQSLIVQSGARP------NIPNWLCGSPGK----YQGIPLKGNIGEYRINERLS----ISVYQESTFNSTKSRCTQRWPTVMVIIMDNRISQLPSCERVKFWHLLNKYLPKHDSHLTFEEDIPSLLKSLSVLSQWSLKGSKRPSPFQSAIVYQIGCGSIPESVINKFKYFEKEDNINHLSKVLS-LPIRGWLIADQIYPATIRKRRHRRNSYLKFTEYSSIFYQQEKQRKEDWKEAQIVVEGSGQ------------FDENWTVPNVDLSRLPIAVSNKTKNETIPYVRKPEKS-QPIIRKSLTNFTVLIGSRKYFQIPPKTFFDAEDGYNQQLKIKAFIRSKESQIDRQISFNPTQWIYFLEKQQAIGLQPRKTDVGSYYITICAYDTDRNRVCDGARLFIKKPKTINRKSYIAAPPGVVWKYPIQATWPDEVKYSNNDSIVIKVQSSSLIEWQGNISRLSLVTEAYTSKEHQIKMVAESQTTGQTLIWKMIVTSVGLNSYVDATSPELVIKLSSFHTNRIPFELINLIKEKL--------IGSISRYWTILKSSSREIFLYKIVKGKE-SFLENSKEAMSILSF--VYSPLQSNPVNCSEVSFSSELVDSMKY-DLRIASNNWNIELIDIIEIPGKCSNYEAFNPIPYQTTS------KPNLISQDHQINAVPDLVNKSINLEVRNGLTFKKIILLPFQNGYAEVLMMELLDINNLVIDESPWVSLLISPYAIYGLPLAENVRSQPYKFKL---KVTLRSGSXXXXXXXXXXXRFELQTDHRFGLIISISEKDTLEFDRARQRFNGNPLKTMNQLLVSQTLSYRWQVVETIARYLHTDQCLLDCGTHIYIHSFSEPKSWQVNISWSML--FDSPDSSDYSTTACSHEXXXXXXXXXXXSDQYTESIISMFLSSIYTFDAYPHQTLVRSLQKNSLGTPTWLTVDPLGSCSNSADKTEINSSEAVFWSNISLNQGNIFAVLLDKKLRINKPKAIYQ-SKIQF---SNGSVWDLGWLKLSHDGRIIYGLPLLSDLVLQSYFSLRIFLDSEEVRENLKYYLSMTVKPSRHSTASTHI-VNLTILPLQNYAKNVFE-LDSKIKLARTINAYLHPSCSLGNRTVYNGFRMFKLEPHKRKHLEFCEKAEDVIIHSIRKRSHDKKVFVDIIWSQVS------------VWSTENGSDSVCNTNSLNDLSGNLF 3878
             +A VG++F ++++ I             + P+WL  + GK     QG+P+  +IG YR++  LS    I+V + +  +  + +C  RWPT+  II+D  +S L   +R+  W+ L   L K  + L   ED+ S  +S+ VL+        R      A+V+QIGCGS+    +   ++ EK   I   S+++  +P+  WL+AD +Y    R RR +R +   +    +    Q  +R  D K +  ++EGSG             F+E+ T+ NV  S++P       K  T+P V  P    +P++R++L+   + I     F+IP +TF+D ++GY+ +L +KA+  S +++   +I  N + WI + +  Q I   P+   +GS+ + +CA+D   N VC+   ++++ P  I + + +    GV+W + + + W D + ++    +   ++ +++  +  + + L ++TEA  S+  +I     +    QTL ++  +    ++   +  S    ++L     N  P   +N IK  L        +G I+ Y         ++ +Y ++  ++   +        I +F  VY P  S   +C + +    LVD++ Y   +    N+ I+ I  I + G C+  +       +T++      KP   +Q    +  P L+    N +V  G  F + + +        V    L+D     + +  W+ L  +   I+GLPL E+VR   YKF +    VT         I            +H   L + I++K   E  + +                  +LS+R Q+++ I + L  D C   C   I +      +   + I WS L   D+          C    LKKL + +          IS +          P Q L   LQK  +G+   + ++ +G+C+       + + + +   NI+   G  F V +     I   K+I Q S +Q    +N +V    WL  S   + +YGLP+L  +     + L IF     V+    + +++   P + S  +  + + L  + +     N+   LD + K+A  +  Y+ P C++    V                ++ C    DVI+ SI +R  + +V  +I WS  S            ++ST N     C    L  L   LF
Sbjct:   34 FSAFVGQIFTMSKTKIRHCVCENYNNKVFSFPDWLMYT-GKGNHNLQGLPVNKDIGTYRVSLTLSSCLIINVNRLNNTDPQQFKCNLRWPTLAAIILDVDLSNLTISQRLNLWNALKLNL-KGAAGLRLLEDVSSFERSIFVLANGLGNSDGRIRSKGVAVVWQIGCGSVEYRHLKTLQWLEKSCLIGEFSQLIGGIPVEMWLVAD-LYDRD-RIRRMKREAL--WQRGKTGLGLQLNERLMDAKYSGTLLEGSGMPRITGGSGDKPSFNESNTIRNV--SKIP-------KIATLPTVVGPPTPFKPVVRRNLSQVVLTIHQINNFKIPRETFYDPQEGYSPKLLVKAYYTSSKTKKKYEIFHNDSYWISYDKDLQNIRFLPKPPHIGSHKLLLCAFDKQDNNVCERLWIYVRPPTPITKSTVLQISAGVLWVHEMPSQWLDGLTFNTTSDLTFAIEGNAIFCYDSSKAILQVLTEAVESRILKITFNITNPKEYQTLKYEFTLAVSDVSPVTNILSDLFQVRLRWTGENLYP---LNSIKSFLSEFALALKMGKIANY-----VDPEDLLIYLVLHSRDFRVISRDMTPDDIFAFQIVYKP--SKNASCEKAA----LVDAVPYIQTKQQLANFYIDSISTIPLKGICNPSQKPTTAHLKTSTVSTTIPKPTPKTQRKPPDFNPSLLID--NFDVEAGFAFMRELNIKAAINEKLVRYFNLIDEEEKNVTDKNWIGLSSNGTFIFGLPLKEHVRKLIYKFWIVLYTVTAHILKASFSINVKPNNWMSRTINHIIRLTLRINDKSE-ENSKIK------------------SLSFRVQLMKEIDKVLRPD-CEYKCAMDILLFDLKIYQKSLILIEWSHLPVLDTDGDLKEIGFQCPWNNLKKLYKNING--------ISNYEIEQRAVQKIPAQALSEELQKAKIGSVVDVKIERMGACAGQVPDLGVINKDLL--PNITAICGLGFRVPIKA---IQMDKSISQLSYVQLYFENNFAVPRTHWLTASASNQFLYGLPMLIHITSGQKYRLHIF-PQNGVKIQSHFLVTVLPNPFQGSKLNHKVTMQLEFISIAPLGDNMITGLDLRWKVASALETYIRPQCTISTTAV---------------DIQECALRFDVILFSI-ERVTNSQVLFEIKWSLRSLLQQTSYKKKREIYSTSNYRQYECPREKLLKLKSMLF 1170
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BLAST of SMED30019358 vs. Planmine SMEST
Match: SMESG000020071.1 (SMESG000020071.1)

HSP 1 Score: 229.18 bits (583), Expect = 1.922e-60
Identity = 279/1187 (23.50%), Postives = 506/1187 (42.63%), Query Frame = 3 
Query:  507 PNWLCGSPGK----YQGIPLKGNIGEYRINERLS----ISVYQESTFNSTKSRCTQRWPTVMVIIMDNRISQLPSCERVKFWHLLNKYLPKHDSHLTFEEDIPSLLKSLSVLSQWSLKGSKRPSPFQSAIVYQIGCGSIPESVINKFKYFEKEDNINHLSKVLS-LPIRGWLIADQIYPATIRKRRHRRNSYLKFTEYSSIFYQQEKQRKEDWKEAQIVVEGSGQ------------FDENWTVPNVDLSRLPIAVSNKTKNETIPYVRKPEKS-QPIIRKSLTNFTVLIGSRKYFQIPPKTFFDAEDGYNQQLKIKAFIRSKESQIDRQISFNPTQWIYFLEKQQAIGLQPRKTDVGSYYITICAYDTDRNRVCDGARLFIKKPKTINRKSYIAAPPGVVWKYPIQATWPDEVKYSNNDSIVIKVQSSSLIEWQGNISRLSLVTEAYTSKEHQIKMVAESQTTGQTLIWKMIVTSVGLNSYVDATSPELVIKLSSFHTNRIPFELINLIKEKL--------IGSISRYWTILKSSSREIFLYKIVKGKE-SFLENSKEAMSILSF--VYSPLQSNPVNCSEVSFSSELVDSMKY-DLRIASNNWNIELIDIIEIPGKCSNYEAFNPIPYQTTS------KPNLISQDHQINAVPDLVNKSINLEVRNGLTFKKIILLPFQNGYAEVLMMELLDINNLVIDESPWVSLLISPYAIYGLPLAENVRSQPYKFKL---KVTLRSGSXXXXXXXXXXXRFELQTDHRFGLIISISEKDTLEFDRARQRFNGNPLKTMNQLLVSQTLSYRWQVVETIARYLHTDQCLLDCGTHIYIHSFSEPKSWQVNISWSML--FDSPDSSDYSTTACSHEXXXXXXXXXXXSDQYTESIISMFLSSIYTFDAYPHQTLVRSLQKNSLGTPTWLTVDPLGSCSNSADKTEINSSEAVFWSNISLNQGNIFAVLLDKKLRINKPKAIYQ-SKIQF---SNGSVWDLGWLKLSHDGRIIYGLPLLSDLVLQSYFSLRIFLDSEEVRENLKYYLSMTVKPSRHSTASTHI-VNLTILPLQNYAKNVFE-LDSKIKLARTINAYLHPSCSLGNRTVYNGFRMFKLEPHKRKHLEFCEKAEDVIIHSIRKRSHDKKVFVDIIWSQVS------------VWSTENGSDSVCNTNSLNDLSGNLF 3878
            P+WL  + GK     QG+P+  +IG YR++  LS    I+V + +  +  + +C  RWPT+  II+D  +S L   +R+  W+ L   L K  + L   ED+ S  +S+ VL+        R      A+V+QIGCGS+    +   ++ EK   I   S+++  +P+  WL+AD +Y    R RR +R +   +    +    Q  +R  D K +  ++EGSG             F+E+ T+ NV  S++P       K  T+P V  P    +P++R++L+   + I     F+IP +TF+D ++GY+ +L +KA+  S +++   +I  N + WI + +  Q I   P+   +GS+ + +CA+D   N VC+   ++++ P  I + + +    GV+W + + + W D + ++    +   ++ +++  +  + + L ++TEA  S+  +I     +    QTL ++  +    ++   +  S    ++L     N  P   +N IK  L        +G I+ Y         ++ +Y ++  ++   +        I +F  VY P  S   +C + +    LVD++ Y   +    N+ I+ I  I + G C+  +       +T++      KP   +Q    +  P L+    N +V  G  F + + +        V    L+D     + +  W+ L  +   I+GLPL E+VR   YKF +    VT         I            +H   L + I++K   E  + +                  +LS+R Q+++ I + L  D C   C   I +      +   + I WS L   D+          C    LKKL + +          IS +          P Q L   LQK  +G+   + ++ +G+C+       + + + +   NI+   G  F V +     I   K+I Q S +Q    +N +V    WL  S   + +YGLP+L  +     + L IF     V+    + +++   P + S  +  + + L  + +     N+   LD + K+A  +  Y+ P C++    V                ++ C    DVI+ SI +R  + +V  +I WS  S            ++ST N     C    L  L   LF
Sbjct:   22 PDWLMYT-GKGNHNLQGLPVNKDIGTYRVSLTLSSCLIINVNRLNNTDPQQFKCNLRWPTLAAIILDVDLSNLTISQRLNLWNALKLNL-KGAAGLRLLEDVSSFERSIFVLANGLGNSDGRIRSKGVAVVWQIGCGSVEYRHLKTLQWLEKSCLIGEFSQLIGGIPVEMWLVAD-LYDRD-RIRRMKREAL--WQRGKTGLGLQLNERLMDAKYSGTLLEGSGMPRITGGSGDKPSFNESNTIRNV--SKIP-------KIATLPTVVGPPTPFKPVVRRNLSQVVLTIHQINNFKIPRETFYDPQEGYSPKLLVKAYYTSSKTKKKYEIFHNDSYWISYDKDLQNIRFLPKPPHIGSHKLLLCAFDKQDNNVCERLWIYVRPPTPITKSTVLQISAGVLWVHEMPSQWLDGLTFNTTSDLTFAIEGNAIFCYDSSKAILQVLTEAVESRILKITFNITNPKEYQTLKYEFTLAVSDVSPVTNILSDLFQVRLRWTGENLYP---LNSIKSFLSEFALALKMGKIANY-----VDPEDLLIYLVLHSRDFRVISRDMTPDDIFAFQIVYKP--SKNASCEKAA----LVDAVPYIQTKQQLANFYIDSISTIPLKGICNPSQKPTTAHLKTSTVSTTIPKPTPKTQRKPPDFNPSLLID--NFDVEAGFAFMRELNIKAAINEKLVRYFNLIDEEEKNVTDKNWIGLSSNGTFIFGLPLKEHVRKLIYKFWIVLYTVTAHILKASFSINVKPNNWMSRTINHIIRLTLRINDKSE-ENSKIK------------------SLSFRVQLMKEIDKVLRPD-CEYKCAMDILLFDLKIYQKSLILIEWSHLPVLDTDGDLKEIGFQCPWNNLKKLYKNING--------ISNYEIEQRAVQKIPAQALSEELQKAKIGSVVDVKIERMGACAGQVPDLGVINKDLL--PNITAICGLGFRVPIKA---IQMDKSISQLSYVQLYFENNFAVPRTHWLTASASNQFLYGLPMLIHITSGQKYRLHIF-PQNGVKIQSHFLVTVLPNPFQGSKLNHKVTMQLEFISIAPLGDNMITGLDLRWKVASALETYIRPQCTISTTAV---------------DIQECALRFDVILFSI-ERVTNSQVLFEIKWSLRSLLQQTSYKKKREIYSTSNYRQYECPREKLLKLKSMLF 1127
[Close]
BLAST of SMED30019358 vs. Planmine SMEST
Match: SMESG000045996.1 (SMESG000045996.1)

HSP 1 Score: 84.3445 bits (207), Expect = 6.346e-16
Identity = 123/573 (21.47%), Postives = 240/573 (41.88%), Query Frame = 3 
Query: 1326 FQIPPKTFFDAEDGYNQQLKIKAFIRSKESQIDRQISFNPTQWIYFLEKQQAIGLQPRKTDVGSYYITICAYDTDRNRVCDGARLFIKKPKTINRKSYIAAP-PGVVWKYPIQATWPDEVKY-SNNDSIVIKVQSSSLIEWQ--GNISRLSLVTEAYTSKEHQIKMVAESQTTGQTLIWKMIVTSVGLNSYVDATSPELVIKLSSFHTNRIPFELINLIKEKLIGSISRYWTILKSSSREIF----LYKIVKGKESFLENSKEAMSILSFVYSPLQSNPVNCSEVSFSSE---LVDSMKY-DLRIAS--NNWNIELID-----------------IIE--IPGKCSNYEAFNPIP-----YQTTSKPNLISQDHQINAVPDLVNKSI------NLEVRNGLTFKKIILLPFQNGYAEVLMMELLDINNLVIDESPWVSLLISPYAIYGLPLAENVRSQPYKFKLKVTLRSGSXXXXXXXXXXXRFELQTDHRFGLIISISEKDTLEFDRARQRFNGNPLKTMNQLLVSQTLSYRWQVVETIARYLHTD-QCLLDCGTHIYIHSFSEPKSWQVN 2909
            + IP  TF D E  +   L+IK F     S  D+ +S +PT+WI + +  Q I + P+ TD+G   + ICAY+     +C    + +  P   + + Y++      + K+ +   W +        D ++IK   +S  +W   GN+  L +   +   +  +I ++   +   +  I  + +  V +N    AT P                         L  S+ ++   ++++S+ +F     +K++K  E ++  S +   I   +++P++S P+   +   + E   + D   Y +L +++  NN  ++L+D                 I+E    G CS     NP+       Q   +  L S D ++    +++NK+       +  V  G+ FK  +L      +  +  M L   +   I+  PW++L  S   +YGLPL ++VR   YKF+  + L++   Q  +       F++   H     +S++ K  L             +KT N   ++  + YRW++V  + +Y+  + + + DCG  + +        W VN
Sbjct:  305 YVIPENTFIDKE--FKSLLRIKVF-----SIEDKIVSNDPTKWISYNQNDQNIRINPKLTDIGETVLKICAYNAFGGYICQSMSISVSPPPPQDHQIYVSKQNKDYIIKHTVPLAWFNRFGVRKRKDVLIIKATGNSPFDWNETGNLEILDVA--SMEGRLIEINLLTLIKNESKIYI-HLTLPVVAINRQKLATGP-------------------------LYRSVFKFREKIQANSKTVFNLTDTWKLLKDLEGYVVKSLKIPKIKIQIFTPIKS-PLFFDKKQGNKENLLVFDWFFYNELSVSTFCNNPKLDLLDQELLFRSFSYFFMVNVTILENRFGGICSFSVDPNPVTKDLSDIQEVKRTTLSSVDLKLATELEIINKTFPKFQYTHFTVTAGIPFKSYVLRRTSLDHNNIKEMRLETSSG--IENEPWIALSASNDFLYGLPLKKHVRESAYKFRFIIKLKNSQTQFKVT------FQVIVVHYDLKAMSMNHKIKLS------------VKTEN---LNIDVQYRWKLVTQLDKYVRENCEAMNDCGKDVAL--------WDVN 810
The following BLAST results are available for this feature:
BLAST of SMED30019358 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30019358 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30019358 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30019358 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30019358 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30019358 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30019358 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30019358 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A5K4F1645.895e-2023.33Uncharacterized protein OS=Schistosoma mansoni OX=... [more]
A0A183MQ491.059e-1925.50Uncharacterized protein OS=Schistosoma margrebowie... [more]
A0A4Z2CPA33.102e-1822.37Dystroglycan isoform 1 OS=Schistosoma japonicum OX... [more]
A0A4Z2CP111.143e-1722.37Dystroglycan isoform 2 OS=Schistosoma japonicum OX... [more]
A0A095AGE46.340e-1528.40Dystroglycan OS=Schistosoma haematobium OX=6185 GN... [more]
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BLAST of SMED30019358 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30019358 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30019358 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30019358 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30019358 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30019358 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 4
Match NameE-valueIdentityDescription
SMESG000017193.10.000e+099.57SMESG000017193.1[more]
SMESG000020071.11.759e-6023.32SMESG000020071.1[more]
SMESG000020071.11.922e-6023.50SMESG000020071.1[more]
SMESG000045996.16.346e-1621.47SMESG000045996.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30019358 ID=SMED30019358|Name=SMED30019358|organism=Schmidtea mediterranea sexual|type=transcript|length=4743bp
TGTCAAATAGTAGTTGTGATACTAATTCAAGTATTCCCGTGTTTCATTGG
CAGTGAATCATGGGGGACATTATTCCCTCAACATTAGCACTCTGTTCTCA
TTGGACAATCGGCTCAAGGTCACAGAGAAACATAAAGAAATAAAAGTCAA
CACACAATCAGTAAACTTTGCAGGTATACAAGAGGCATACAAACCCATCT
CCCAGTACAAATAATGGGAATATTTCCAATGTATAGCATATGATATCCAG
TAGTAAAATTGAGATGGATTTCTCCGATTCATTTAAACAAATTAAACACG
CCTCATAACAGAAAACAAATTTGGATATTTAAAACATTCGCAACAATTCT
CGCGTTGTATTCGAAATGATTTTACATGTGCTTCTGATTTTACGGATAAT
TTTATCGCATTCCTCACTCAGTGCGGCAACCTTGAACGCAGTTGTCGGGA
AACTCTTTCACATAAACCAGTCGTTAATCGTCCAGTCTGGAGCTAGACCA
AATATACCAAATTGGTTATGTGGGTCCCCTGGAAAATATCAAGGCATCCC
ATTAAAAGGAAATATAGGCGAATATCGTATAAATGAAAGATTATCAATTT
CGGTTTATCAAGAATCAACTTTTAATTCAACTAAATCCAGATGCACTCAA
AGATGGCCGACAGTAATGGTAATTATTATGGACAACAGAATATCCCAACT
TCCCAGTTGTGAACGAGTGAAGTTTTGGCACTTACTTAACAAATATCTGC
CTAAACATGATTCCCACCTGACATTTGAAGAAGACATTCCTAGCTTGTTA
AAATCCCTGTCGGTTCTATCCCAGTGGAGCTTGAAAGGTTCTAAACGTCC
TTCTCCCTTCCAATCAGCTATAGTTTACCAAATAGGATGCGGATCCATTC
CGGAATCTGTAATTAACAAATTCAAATATTTCGAAAAGGAGGACAACATC
AATCATCTATCAAAGGTACTATCCTTACCAATCCGTGGATGGCTGATAGC
CGACCAGATCTACCCGGCAACAATCAGAAAACGTCGGCATCGCCGGAATA
GTTATTTGAAATTCACAGAATATTCGTCGATTTTCTATCAACAAGAAAAA
CAACGTAAAGAAGATTGGAAAGAAGCCCAAATTGTTGTCGAAGGATCCGG
ACAATTTGATGAGAATTGGACCGTTCCGAATGTCGATTTGTCAAGACTGC
CAATTGCTGTCTCTAACAAAACGAAAAATGAAACAATTCCTTATGTTAGG
AAACCAGAAAAGTCTCAGCCGATTATCAGAAAAAGTCTTACTAATTTTAC
GGTCCTTATTGGGTCCAGAAAATACTTTCAAATTCCACCTAAAACCTTTT
TTGATGCCGAAGATGGATACAATCAGCAATTGAAAATAAAAGCTTTTATC
CGGTCCAAGGAATCTCAAATTGACAGACAGATAAGTTTCAACCCGACCCA
ATGGATATATTTTCTAGAAAAGCAGCAAGCAATCGGATTGCAGCCTCGGA
AAACTGACGTAGGATCTTATTATATTACCATTTGTGCCTATGATACGGAT
AGAAATAGAGTTTGCGATGGGGCCAGACTGTTTATCAAAAAGCCAAAGAC
AATTAATCGAAAATCTTACATTGCTGCTCCTCCGGGAGTGGTTTGGAAGT
ACCCGATTCAGGCCACCTGGCCAGACGAGGTGAAATATTCAAACAACGAT
TCCATTGTCATAAAAGTTCAAAGTTCCAGTCTAATAGAATGGCAGGGAAA
TATTTCGCGATTATCTCTCGTCACGGAAGCGTACACGTCAAAGGAACACC
AAATCAAAATGGTGGCAGAAAGTCAAACCACCGGGCAAACCTTGATTTGG
AAGATGATCGTAACCTCTGTCGGGCTGAACTCTTACGTGGATGCCACAAG
TCCAGAACTCGTCATAAAACTTTCATCCTTCCATACTAACCGAATCCCGT
TTGAATTGATAAATCTCATAAAGGAAAAGCTAATCGGCTCTATTTCCCGC
TACTGGACAATTCTTAAGTCATCAAGTCGAGAAATATTTCTTTACAAAAT
TGTAAAAGGCAAAGAAAGTTTCCTCGAAAATTCAAAAGAGGCTATGTCCA
TTTTGTCGTTTGTCTATTCTCCGTTACAATCAAATCCTGTCAATTGTTCA
GAGGTCTCCTTTTCAAGTGAATTGGTAGACAGCATGAAATATGATTTAAG
GATAGCTTCAAACAATTGGAACATCGAGCTGATAGACATCATAGAGATAC
CTGGAAAGTGCTCCAATTATGAAGCTTTCAACCCGATTCCTTATCAAACG
ACTTCGAAACCAAATCTCATTTCTCAGGACCATCAAATTAATGCCGTTCC
CGATCTAGTAAACAAGTCCATCAATTTAGAAGTTCGAAATGGACTCACGT
TCAAGAAAATAATATTATTACCTTTTCAAAATGGATATGCCGAAGTTTTA
ATGATGGAACTCCTCGATATCAATAATCTTGTAATTGATGAATCGCCATG
GGTCTCTCTTTTGATCTCGCCATATGCAATTTATGGTTTGCCCCTGGCAG
AAAATGTCAGATCACAGCCTTATAAGTTCAAACTGAAGGTGACTCTGCGA
TCGGGAAGTGTCCAAGAGGTAATTGTCAACATTGTCGTGGTCAGATTCGA
GCTGCAGACCGACCATAGGTTTGGACTGATTATTAGCATATCTGAGAAGG
ACACTCTAGAATTCGACAGAGCTCGACAGCGATTCAACGGAAACCCACTG
AAAACAATGAACCAGCTGCTCGTTAGCCAGACTCTCTCATATCGGTGGCA
AGTCGTAGAAACGATTGCCCGTTATTTGCATACCGACCAATGCTTGCTGG
ATTGCGGAACCCATATTTACATTCACAGCTTTTCAGAACCAAAAAGCTGG
CAAGTAAATATTTCATGGTCAATGCTCTTTGACTCTCCAGACTCGTCCGA
CTATTCCACAACCGCGTGTTCACATGAGAAACTGAAAAAACTTATTCGGC
TTCTCATCAAGTCAGACCAATACACTGAGTCCATCATTTCAATGTTTCTG
TCCTCAATATACACTTTTGATGCTTATCCGCACCAAACTCTTGTCAGATC
TCTTCAGAAAAACTCCCTAGGAACTCCAACATGGCTCACAGTGGATCCGC
TAGGCTCATGTTCCAACAGCGCAGACAAAACCGAAATCAATTCATCAGAA
GCTGTATTTTGGTCCAATATATCATTGAATCAAGGGAACATTTTTGCTGT
CCTCCTCGATAAAAAGCTGAGAATAAATAAACCAAAGGCAATTTATCAGT
CGAAAATTCAATTTTCAAATGGCAGCGTTTGGGATTTGGGGTGGCTGAAG
CTGTCTCATGACGGGAGAATTATTTATGGGCTGCCGTTGTTATCAGATCT
CGTGTTGCAGTCTTACTTTTCCTTGCGAATTTTCCTCGATTCGGAAGAAG
TGAGAGAAAATCTTAAATATTATCTTTCAATGACCGTCAAACCGAGTCGA
CATTCAACGGCGAGTACGCACATTGTCAACTTGACGATATTACCGCTTCA
AAATTATGCCAAAAATGTTTTCGAGTTAGATTCTAAAATAAAACTCGCCA
GAACAATCAACGCATATCTGCATCCTTCATGTTCTTTGGGCAACAGGACA
GTGTATAATGGCTTCAGGATGTTTAAACTTGAACCACACAAAAGAAAGCA
TTTAGAGTTCTGTGAAAAAGCAGAAGATGTTATTATACATTCAATTCGCA
AAAGGTCACATGATAAAAAAGTATTTGTTGATATTATATGGAGTCAAGTT
TCAGTTTGGTCAACGGAAAACGGTTCTGATTCCGTTTGCAATACCAATTC
CTTGAACGACCTCAGTGGGAATTTGTTTCAAAACTTTTCGACTCAGGAAA
TAAACCAAGAGCTTGTGAGTTATTTTGAAAATTCCGGAATTGGTCAGATC
CTGCAAACTCAACTTATTTTGTTTGACCAATGTCTGAAGGCCGTTAAAAG
ATTCAACTTAGACATCCCTTACTCGCCTGTGCCAAAAGATTATCAAATAA
AGCCGTTGACAACGACTCAAGCATCGACAAAAATTGTCGTTGGAGTTCTA
TTTTTTATACTGATTTTTATTTCTTCTATTTGTATTATATTCTATTTTGT
GAAGCGCGGGATTCCCACTACTTTTACTCAGTTGACAGAGAAGACCAACA
AGTCAATGGCTCTGGAAGATTTTAACAAAAGCCCCATAAACAGCCCAGTG
TCCAGCTTCATTAAAAAGCCAAAAAATAATCCAACTTTAGACGGTTTCGG
ACCAAGCTTATCAAATAACTCACCTAAGACCCCGCTGCTTTCTCAGTTCT
CAAGAGACGATTCAAAATCCGAAAGGCAAAAAGAGCCAGCATTCAATGAT
GAAGAAGCAATAGGTTCATACAGTTATGCTGCCCGACATCCGAAATCCCC
GGAACCGGAAGTTGCATCCAACAATTCCATAGGCATATCGAAACAACCGG
CCACCAGCAATGTCATCAGAAATCCTGCCATGATGATGGGCAGTCGGTTG
AATCCTTATCGCAACATTCCGCCTCCAATAATTTAGATCATTACAAACAT
TGTTTTTACTTTAGTCTTACATGAATTATTTTACAGATTCTCAGAAAATG
GAAAAATTTGTCAAAAAAATAAATTATTCATAACAAAACTTCAGAATTAT
TAAAGGATTAAAAATAAATTATGTTAATTTAAAAAGAAAAAAT
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protein sequence of SMED30019358-orf-1

>SMED30019358-orf-1 ID=SMED30019358-orf-1|Name=SMED30019358-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1407bp
MILHVLLILRIILSHSSLSAATLNAVVGKLFHINQSLIVQSGARPNIPNW
LCGSPGKYQGIPLKGNIGEYRINERLSISVYQESTFNSTKSRCTQRWPTV
MVIIMDNRISQLPSCERVKFWHLLNKYLPKHDSHLTFEEDIPSLLKSLSV
LSQWSLKGSKRPSPFQSAIVYQIGCGSIPESVINKFKYFEKEDNINHLSK
VLSLPIRGWLIADQIYPATIRKRRHRRNSYLKFTEYSSIFYQQEKQRKED
WKEAQIVVEGSGQFDENWTVPNVDLSRLPIAVSNKTKNETIPYVRKPEKS
QPIIRKSLTNFTVLIGSRKYFQIPPKTFFDAEDGYNQQLKIKAFIRSKES
QIDRQISFNPTQWIYFLEKQQAIGLQPRKTDVGSYYITICAYDTDRNRVC
DGARLFIKKPKTINRKSYIAAPPGVVWKYPIQATWPDEVKYSNNDSIVIK
VQSSSLIEWQGNISRLSLVTEAYTSKEHQIKMVAESQTTGQTLIWKMIVT
SVGLNSYVDATSPELVIKLSSFHTNRIPFELINLIKEKLIGSISRYWTIL
KSSSREIFLYKIVKGKESFLENSKEAMSILSFVYSPLQSNPVNCSEVSFS
SELVDSMKYDLRIASNNWNIELIDIIEIPGKCSNYEAFNPIPYQTTSKPN
LISQDHQINAVPDLVNKSINLEVRNGLTFKKIILLPFQNGYAEVLMMELL
DINNLVIDESPWVSLLISPYAIYGLPLAENVRSQPYKFKLKVTLRSGSVQ
EVIVNIVVVRFELQTDHRFGLIISISEKDTLEFDRARQRFNGNPLKTMNQ
LLVSQTLSYRWQVVETIARYLHTDQCLLDCGTHIYIHSFSEPKSWQVNIS
WSMLFDSPDSSDYSTTACSHEKLKKLIRLLIKSDQYTESIISMFLSSIYT
FDAYPHQTLVRSLQKNSLGTPTWLTVDPLGSCSNSADKTEINSSEAVFWS
NISLNQGNIFAVLLDKKLRINKPKAIYQSKIQFSNGSVWDLGWLKLSHDG
RIIYGLPLLSDLVLQSYFSLRIFLDSEEVRENLKYYLSMTVKPSRHSTAS
THIVNLTILPLQNYAKNVFELDSKIKLARTINAYLHPSCSLGNRTVYNGF
RMFKLEPHKRKHLEFCEKAEDVIIHSIRKRSHDKKVFVDIIWSQVSVWST
ENGSDSVCNTNSLNDLSGNLFQNFSTQEINQELVSYFENSGIGQILQTQL
ILFDQCLKAVKRFNLDIPYSPVPKDYQIKPLTTTQASTKIVVGVLFFILI
FISSICIIFYFVKRGIPTTFTQLTEKTNKSMALEDFNKSPINSPVSSFIK
KPKNNPTLDGFGPSLSNNSPKTPLLSQFSRDDSKSERQKEPAFNDEEAIG
SYSYAARHPKSPEPEVASNNSIGISKQPATSNVIRNPAMMMGSRLNPYRN
IPPPII*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000017photoreceptor neuron
PLANA:0000099neuron
PLANA:0000418head
Vocabulary: INTERPRO
TermDefinition
IPR027468Alpha-dystroglycan_domain_2
IPR013783Ig-like_fold
Vocabulary: molecular function
TermDefinition
GO:0005509calcium ion binding
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR027468Alpha-dystroglycan domain 2GENE3DG3DSA:3.30.70.1040coord: 93..229
e-value: 4.2E-7
score: 32.3
IPR027468Alpha-dystroglycan domain 2SUPERFAMILYSSF111006Dystroglycan, domain 2coord: 98..213
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1364..1386
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1310..1386
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1330..1344
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1310..1329
NoneNo IPR availablePANTHERPTHR21559:SF21DYSTROGLYCAN, ISOFORM Dcoord: 17..230
coord: 695..885
NoneNo IPR availablePANTHERPTHR21559:SF21DYSTROGLYCAN, ISOFORM Dcoord: 284..396
NoneNo IPR availablePANTHERPTHR21559DYSTROGLYCAN-RELATEDcoord: 284..396
NoneNo IPR availablePANTHERPTHR21559DYSTROGLYCAN-RELATEDcoord: 17..230
coord: 695..885
NoneNo IPR availableSIGNALP_EUKSignalP-noTMSignalP-noTMcoord: 1..21
score: 0.756
NoneNo IPR availableTMHMMTMhelixcoord: 1240..1262