WH1 domain-containing protein

Overview
NameWH1 domain-containing protein
Smed IDSMED30019353
Length (bp)1470
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of WH1 domain-containing protein (SMED30019353) t-SNE clustered cells

Violin plots show distribution of expression levels for WH1 domain-containing protein (SMED30019353) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of WH1 domain-containing protein (SMED30019353) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for WH1 domain-containing protein (SMED30019353) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30019353

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 5

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
intestinal phagocyteSMED30019353h1SMcG0019994 Contig668GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
posterior sideSMED30019353h1SMcG0019994 dd_Smed_v4_4597_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
posterior muscle cellSMED30019353h1SMcG0019994 dd_Smed_v4_4597_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
testisSMED30019353h1SMcG0019994 SMED30019353smed_20140614PMID:279364
whole organism adult hermaphrodite colorimetric in situ hybridization evidence
copulatory apparatusSMED30019353h1SMcG0019994 SMED30019353smed_20140614PMID:279364
whole organism adult hermaphrodite colorimetric in situ hybridization evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of WH1 domain-containing protein vs. Ensembl Human
Match: HOMER1 (homer scaffold protein 1 [Source:HGNC Symbol;Acc:HGNC:17512])

HSP 1 Score: 141.354 bits (355), Expect = 3.819e-39
Identity = 63/115 (54.78%), Postives = 81/115 (70.43%), Query Frame = 2 
Query:   86 MGELPIFTAHAHVFTIDPKTKKTWIPSSSKAVEINYFFDPTKNCFRIVSIEDTSNGKQVIINSTLTEKMVFKKTSQKFGQWTDSKQCTIFGLGFNSEDDLDAFVEKFKSCIETMR 430
            MGE PIF+  AHVF IDP TKK W+P+S  AV ++YF+D T+N +RI+S++    G + IINST+T  M F KTSQKFGQW DS+  T++GLGF+SE  L  F EKF+   E  R
Sbjct:    1 MGEQPIFSTRAHVFQIDPNTKKNWVPTSKHAVTVSYFYDSTRNVYRIISLD----GSKAIINSTITPNMTFTKTSQKFGQWADSRANTVYGLGFSSEHHLSKFAEKFQEFKEAAR 111
[Close]
BLAST of WH1 domain-containing protein vs. Ensembl Human
Match: HOMER2 (homer scaffold protein 2 [Source:HGNC Symbol;Acc:HGNC:17513])

HSP 1 Score: 146.747 bits (369), Expect = 4.014e-39
Identity = 65/115 (56.52%), Postives = 83/115 (72.17%), Query Frame = 2 
Query:   86 MGELPIFTAHAHVFTIDPKTKKTWIPSSSKAVEINYFFDPTKNCFRIVSIEDTSNGKQVIINSTLTEKMVFKKTSQKFGQWTDSKQCTIFGLGFNSEDDLDAFVEKFKSCIETMR 430
            MGE PIFT  AHVF IDP TKK W+P+S +AV ++YF+D T+N +RI+S+    +G +VIINST+T  M F KTSQKFGQW DS+  T+FGLGF+SE  L  F EKF+   E  +
Sbjct:    1 MGEQPIFTTRAHVFQIDPNTKKNWMPASKQAVTVSYFYDVTRNSYRIISV----DGAKVIINSTITPNMTFTKTSQKFGQWADSRANTVFGLGFSSEQQLTKFAEKFQEVKEAAK 111
[Close]
BLAST of WH1 domain-containing protein vs. Ensembl Human
Match: HOMER2 (homer scaffold protein 2 [Source:HGNC Symbol;Acc:HGNC:17513])

HSP 1 Score: 146.362 bits (368), Expect = 4.113e-39
Identity = 65/115 (56.52%), Postives = 83/115 (72.17%), Query Frame = 2 
Query:   86 MGELPIFTAHAHVFTIDPKTKKTWIPSSSKAVEINYFFDPTKNCFRIVSIEDTSNGKQVIINSTLTEKMVFKKTSQKFGQWTDSKQCTIFGLGFNSEDDLDAFVEKFKSCIETMR 430
            MGE PIFT  AHVF IDP TKK W+P+S +AV ++YF+D T+N +RI+S+    +G +VIINST+T  M F KTSQKFGQW DS+  T+FGLGF+SE  L  F EKF+   E  +
Sbjct:    1 MGEQPIFTTRAHVFQIDPNTKKNWMPASKQAVTVSYFYDVTRNSYRIISV----DGAKVIINSTITPNMTFTKTSQKFGQWADSRANTVFGLGFSSEQQLTKFAEKFQEVKEAAK 111
[Close]
BLAST of WH1 domain-containing protein vs. Ensembl Human
Match: HOMER1 (homer scaffold protein 1 [Source:HGNC Symbol;Acc:HGNC:17512])

HSP 1 Score: 143.28 bits (360), Expect = 7.908e-38
Identity = 63/115 (54.78%), Postives = 81/115 (70.43%), Query Frame = 2 
Query:   86 MGELPIFTAHAHVFTIDPKTKKTWIPSSSKAVEINYFFDPTKNCFRIVSIEDTSNGKQVIINSTLTEKMVFKKTSQKFGQWTDSKQCTIFGLGFNSEDDLDAFVEKFKSCIETMR 430
            MGE PIF+  AHVF IDP TKK W+P+S  AV ++YF+D T+N +RI+S+    +G + IINST+T  M F KTSQKFGQW DS+  T++GLGF+SE  L  F EKF+   E  R
Sbjct:    1 MGEQPIFSTRAHVFQIDPNTKKNWVPTSKHAVTVSYFYDSTRNVYRIISL----DGSKAIINSTITPNMTFTKTSQKFGQWADSRANTVYGLGFSSEHHLSKFAEKFQEFKEAAR 111
[Close]
BLAST of WH1 domain-containing protein vs. Ensembl Human
Match: HOMER3 (homer scaffold protein 3 [Source:HGNC Symbol;Acc:HGNC:17514])

HSP 1 Score: 134.806 bits (338), Expect = 5.783e-37
Identity = 60/113 (53.10%), Postives = 76/113 (67.26%), Query Frame = 2 
Query:   92 ELPIFTAHAHVFTIDPKTKKTWIPSSSKAVEINYFFDPTKNCFRIVSIEDTSNGKQVIINSTLTEKMVFKKTSQKFGQWTDSKQCTIFGLGFNSEDDLDAFVEKFKSCIETMR 430
            E PIF+  AHVF IDP TK+ WIP+   A+ ++YF+D T+N +RI+SI     G + IINST+T  M F KTSQKFGQW DS+  T++GLGF SE  L  F EKF+   E  R
Sbjct:    6 EQPIFSTRAHVFQIDPATKRNWIPAGKHALTVSYFYDATRNVYRIISI----GGAKAIINSTVTPNMTFTKTSQKFGQWADSRANTVYGLGFASEQHLTQFAEKFQEVKEAAR 114
[Close]
BLAST of WH1 domain-containing protein vs. Ensembl Fly
Match: homer (gene:FBgn0025777 transcript:FBtr0079306)

HSP 1 Score: 145.206 bits (365), Expect = 1.767e-38
Identity = 72/153 (47.06%), Postives = 100/153 (65.36%), Query Frame = 2 
Query:   86 MGELPIFTAHAHVFTIDPKTKKTWIPSSSKAVEINYFFDPTKNCFRIVSIEDTSNGKQVIINSTLTEKMVFKKTSQKFGQWTDSKQCTIFGLGFNSEDDLDAFVEKFKSCIETMRN--KSAPNHN-----DNANNKEVNKRELLGLNNNVVGI 523
            MGE PIFT  AHVF IDPKTK+TWI +S KAV +++F+D ++N +RI+S+E    G + +INST+T  M F +TSQKFGQW+D +  T++GLGF SE +L  FVEKF+   E  +N  KSA   N      +AN   ++ R +  + N+   I
Sbjct:    1 MGEQPIFTCQAHVFHIDPKTKRTWITASMKAVNVSFFYDSSRNLYRIISVE----GTKAVINSTITPNMTFTQTSQKFGQWSDVRANTVYGLGFASEAELTKFVEKFQEVKEATKNAMKSANGSNAVTPTTSANTSPISGRAVGSMQNDNTAI 149
[Close]
BLAST of WH1 domain-containing protein vs. Ensembl Fly
Match: homer (gene:FBgn0025777 transcript:FBtr0329892)

HSP 1 Score: 145.206 bits (365), Expect = 1.767e-38
Identity = 72/153 (47.06%), Postives = 100/153 (65.36%), Query Frame = 2 
Query:   86 MGELPIFTAHAHVFTIDPKTKKTWIPSSSKAVEINYFFDPTKNCFRIVSIEDTSNGKQVIINSTLTEKMVFKKTSQKFGQWTDSKQCTIFGLGFNSEDDLDAFVEKFKSCIETMRN--KSAPNHN-----DNANNKEVNKRELLGLNNNVVGI 523
            MGE PIFT  AHVF IDPKTK+TWI +S KAV +++F+D ++N +RI+S+E    G + +INST+T  M F +TSQKFGQW+D +  T++GLGF SE +L  FVEKF+   E  +N  KSA   N      +AN   ++ R +  + N+   I
Sbjct:    1 MGEQPIFTCQAHVFHIDPKTKRTWITASMKAVNVSFFYDSSRNLYRIISVE----GTKAVINSTITPNMTFTQTSQKFGQWSDVRANTVYGLGFASEAELTKFVEKFQEVKEATKNAMKSANGSNAVTPTTSANTSPISGRAVGSMQNDNTAI 149
[Close]
BLAST of WH1 domain-containing protein vs. Ensembl Fly
Match: homer (gene:FBgn0025777 transcript:FBtr0329893)

HSP 1 Score: 145.976 bits (367), Expect = 7.390e-38
Identity = 72/153 (47.06%), Postives = 100/153 (65.36%), Query Frame = 2 
Query:   86 MGELPIFTAHAHVFTIDPKTKKTWIPSSSKAVEINYFFDPTKNCFRIVSIEDTSNGKQVIINSTLTEKMVFKKTSQKFGQWTDSKQCTIFGLGFNSEDDLDAFVEKFKSCIETMRN--KSAPNHN-----DNANNKEVNKRELLGLNNNVVGI 523
            MGE PIFT  AHVF IDPKTK+TWI +S KAV +++F+D ++N +RI+S+E    G + +INST+T  M F +TSQKFGQW+D +  T++GLGF SE +L  FVEKF+   E  +N  KSA   N      +AN   ++ R +  + N+   I
Sbjct:    1 MGEQPIFTCQAHVFHIDPKTKRTWITASMKAVNVSFFYDSSRNLYRIISVE----GTKAVINSTITPNMTFTQTSQKFGQWSDVRANTVYGLGFASEAELTKFVEKFQEVKEATKNAMKSANGSNAVTPTTSANTSPISGRAVGSMQNDNTAI 149
[Close]
BLAST of WH1 domain-containing protein vs. Ensembl Fly
Match: homer (gene:FBgn0025777 transcript:FBtr0333346)

HSP 1 Score: 140.969 bits (354), Expect = 5.670e-37
Identity = 70/153 (45.75%), Postives = 99/153 (64.71%), Query Frame = 2 
Query:   86 MGELPIFTAHAHVFTIDPKTKKTWIPSSSKAVEINYFFDPTKNCFRIVSIEDTSNGKQVIINSTLTEKMVFKKTSQKFGQWTDSKQCTIFGLGFNSEDDLDAFVEKFKSCIETMRN--KSAPNHN-----DNANNKEVNKRELLGLNNNVVGI 523
            + E PIFT  AHVF IDPKTK+TWI +S KAV +++F+D ++N +RI+S+E    G + +INST+T  M F +TSQKFGQW+D +  T++GLGF SE +L  FVEKF+   E  +N  KSA   N      +AN   ++ R +  + N+   I
Sbjct:    7 LSEQPIFTCQAHVFHIDPKTKRTWITASMKAVNVSFFYDSSRNLYRIISVE----GTKAVINSTITPNMTFTQTSQKFGQWSDVRANTVYGLGFASEAELTKFVEKFQEVKEATKNAMKSANGSNAVTPTTSANTSPISGRAVGSMQNDNTAI 155
[Close]
BLAST of WH1 domain-containing protein vs. Ensembl Fly
Match: homer (gene:FBgn0025777 transcript:FBtr0332330)

HSP 1 Score: 140.969 bits (354), Expect = 6.430e-37
Identity = 70/153 (45.75%), Postives = 99/153 (64.71%), Query Frame = 2 
Query:   86 MGELPIFTAHAHVFTIDPKTKKTWIPSSSKAVEINYFFDPTKNCFRIVSIEDTSNGKQVIINSTLTEKMVFKKTSQKFGQWTDSKQCTIFGLGFNSEDDLDAFVEKFKSCIETMRN--KSAPNHN-----DNANNKEVNKRELLGLNNNVVGI 523
            + E PIFT  AHVF IDPKTK+TWI +S KAV +++F+D ++N +RI+S+E    G + +INST+T  M F +TSQKFGQW+D +  T++GLGF SE +L  FVEKF+   E  +N  KSA   N      +AN   ++ R +  + N+   I
Sbjct:    4 LSEQPIFTCQAHVFHIDPKTKRTWITASMKAVNVSFFYDSSRNLYRIISVE----GTKAVINSTITPNMTFTQTSQKFGQWSDVRANTVYGLGFASEAELTKFVEKFQEVKEATKNAMKSANGSNAVTPTTSANTSPISGRAVGSMQNDNTAI 152
[Close]
BLAST of WH1 domain-containing protein vs. Ensembl Zebrafish
Match: homer1b (homer scaffold protein 1b [Source:ZFIN;Acc:ZDB-GENE-040801-44])

HSP 1 Score: 139.043 bits (349), Expect = 1.818e-36
Identity = 61/115 (53.04%), Postives = 80/115 (69.57%), Query Frame = 2 
Query:   86 MGELPIFTAHAHVFTIDPKTKKTWIPSSSKAVEINYFFDPTKNCFRIVSIEDTSNGKQVIINSTLTEKMVFKKTSQKFGQWTDSKQCTIFGLGFNSEDDLDAFVEKFKSCIETMR 430
            MGE PI++  AHVF IDP TKK W+P+S  AV ++YF+D T+N +RI+S+    +G + IINST+T  M F KTSQKFGQW DS+  T++GLGF+SE  L  F +KF    E  R
Sbjct:    1 MGEQPIYSTRAHVFQIDPSTKKNWMPTSKHAVTVSYFYDSTRNVYRIISL----DGSKAIINSTITPNMSFTKTSQKFGQWADSRANTVYGLGFSSEHHLAKFADKFAEYKEAAR 111
[Close]
BLAST of WH1 domain-containing protein vs. Ensembl Zebrafish
Match: homer3b (homer scaffold protein 3b [Source:ZFIN;Acc:ZDB-GENE-040426-739])

HSP 1 Score: 135.191 bits (339), Expect = 4.662e-35
Identity = 58/115 (50.43%), Postives = 79/115 (68.70%), Query Frame = 2 
Query:   86 MGELPIFTAHAHVFTIDPKTKKTWIPSSSKAVEINYFFDPTKNCFRIVSIEDTSNGKQVIINSTLTEKMVFKKTSQKFGQWTDSKQCTIFGLGFNSEDDLDAFVEKFKSCIETMR 430
            MGE P+++  AHVF IDP TK+ WIP+S  AV +++FFD  ++ +RI+S+     G + IINST+T  M F KTSQKFGQW DS+  T++GLGF++E  L  F E+FK   E  R
Sbjct:    1 MGEQPLYSVKAHVFQIDPATKRNWIPASKHAVTVSFFFDAGRSVYRIISV----GGTKAIINSTITPNMTFTKTSQKFGQWADSRANTVYGLGFSTEQQLQQFSEQFKEFKEAAR 111
[Close]
BLAST of WH1 domain-containing protein vs. Ensembl Zebrafish
Match: homer3b (homer scaffold protein 3b [Source:ZFIN;Acc:ZDB-GENE-040426-739])

HSP 1 Score: 135.191 bits (339), Expect = 5.213e-35
Identity = 58/115 (50.43%), Postives = 79/115 (68.70%), Query Frame = 2 
Query:   86 MGELPIFTAHAHVFTIDPKTKKTWIPSSSKAVEINYFFDPTKNCFRIVSIEDTSNGKQVIINSTLTEKMVFKKTSQKFGQWTDSKQCTIFGLGFNSEDDLDAFVEKFKSCIETMR 430
            MGE P+++  AHVF IDP TK+ WIP+S  AV +++FFD  ++ +RI+S+     G + IINST+T  M F KTSQKFGQW DS+  T++GLGF++E  L  F E+FK   E  R
Sbjct:    1 MGEQPLYSVKAHVFQIDPATKRNWIPASKHAVTVSFFFDAGRSVYRIISV----GGTKAIINSTITPNMTFTKTSQKFGQWADSRANTVYGLGFSTEQQLQQFSEQFKEFKEAAR 111
[Close]
BLAST of WH1 domain-containing protein vs. Ensembl Zebrafish
Match: homer1b (homer scaffold protein 1b [Source:ZFIN;Acc:ZDB-GENE-040801-44])

HSP 1 Score: 133.265 bits (334), Expect = 4.786e-34
Identity = 59/113 (52.21%), Postives = 78/113 (69.03%), Query Frame = 2 
Query:   92 ELPIFTAHAHVFTIDPKTKKTWIPSSSKAVEINYFFDPTKNCFRIVSIEDTSNGKQVIINSTLTEKMVFKKTSQKFGQWTDSKQCTIFGLGFNSEDDLDAFVEKFKSCIETMR 430
            E PI++  AHVF IDP TKK W+P+S  AV ++YF+D T+N +RI+S+    +G + IINST+T  M F KTSQKFGQW DS+  T++GLGF+SE  L  F +KF    E  R
Sbjct:   41 EQPIYSTRAHVFQIDPSTKKNWMPTSKHAVTVSYFYDSTRNVYRIISL----DGSKAIINSTITPNMSFTKTSQKFGQWADSRANTVYGLGFSSEHHLAKFADKFAEYKEAAR 149
[Close]
BLAST of WH1 domain-containing protein vs. Ensembl Zebrafish
Match: homer3a (homer scaffold protein 3a [Source:ZFIN;Acc:ZDB-GENE-170413-3])

HSP 1 Score: 115.931 bits (289), Expect = 1.106e-30
Identity = 52/108 (48.15%), Postives = 72/108 (66.67%), Query Frame = 2 
Query:   92 ELPIFTAHAHVFTIDPKTKKTWIPSSSKAVEINYFFDPTKNCFRIVSIEDTSNGKQVIINSTLTEKMVFKKTSQKFGQWTDSKQCTIFGLGFNSEDDLDAFVEKFKSC 415
            E PIF++ AHVF IDP TK+ WIP+S  AV +++F+D  ++ +RI+S+     G + IINST++  M F KTSQKFGQW DS+  T++GLGF +E  L  F      C
Sbjct:    2 EQPIFSSRAHVFQIDPATKRNWIPASKHAVTVSFFYDANRHAYRIISV----GGTKAIINSTISPNMTFTKTSQKFGQWADSRANTVYGLGFATEQQLGFFFSLISHC 105
[Close]
BLAST of WH1 domain-containing protein vs. Ensembl Xenopus
Match: ldhb (lactate dehydrogenase B [Source:Xenbase;Acc:XB-GENE-5908187])

HSP 1 Score: 145.206 bits (365), Expect = 2.181e-38
Identity = 68/138 (49.28%), Postives = 93/138 (67.39%), Query Frame = 2 
Query:   86 MGELPIFTAHAHVFTIDPKTKKTWIPSSSKAVEINYFFDPTKNCFRIVSIEDTSNGKQVIINSTLTEKMVFKKTSQKFGQWTDSKQCTIFGLGFNSEDDLDAFVEKFKSCIET---MRNKSAPNHNDNANNKEVNKRE 490
            MGE PIFT  AHVF IDP TKK W+P+S +AV ++YF+D T+N +RI+S+    +G +VIINST++  M F KTSQKFGQW DS+  T+FGLGF SE  L  F +KF+   E     R++S      ++N+ + + RE
Sbjct:   29 MGEQPIFTTKAHVFQIDPSTKKNWVPASKQAVSVSYFYDSTRNSYRIISV----DGTKVIINSTISPNMTFTKTSQKFGQWADSRANTVFGLGFASEQQLSKFADKFQEVKEAAKLARDRSQEKMETSSNHSQESGRE 162
[Close]
BLAST of WH1 domain-containing protein vs. Ensembl Xenopus
Match: homer1 (prolactin-releasing peptide receptor-like [Source:Xenbase;Acc:XB-GENE-994603])

HSP 1 Score: 141.354 bits (355), Expect = 3.123e-37
Identity = 62/115 (53.91%), Postives = 81/115 (70.43%), Query Frame = 2 
Query:   86 MGELPIFTAHAHVFTIDPKTKKTWIPSSSKAVEINYFFDPTKNCFRIVSIEDTSNGKQVIINSTLTEKMVFKKTSQKFGQWTDSKQCTIFGLGFNSEDDLDAFVEKFKSCIETMR 430
            MGE PIF+  AHVF IDP TKK W+P+S  AV ++YF+D T+N +RI+S+    +G + IINST++  M F KTSQKFGQW DS+  T++GLGF+SE  L  F EKF+   E  R
Sbjct:    1 MGEQPIFSTRAHVFQIDPNTKKNWVPTSKHAVTVSYFYDSTRNVYRIISL----DGSKAIINSTISPNMTFTKTSQKFGQWADSRANTVYGLGFSSEHHLTKFAEKFQEFKEAAR 111
[Close]
BLAST of WH1 domain-containing protein vs. Ensembl Xenopus
Match: rhag (Rh associated glycoprotein [Source:Xenbase;Acc:XB-GENE-983543])

HSP 1 Score: 138.658 bits (348), Expect = 3.999e-36
Identity = 61/113 (53.98%), Postives = 78/113 (69.03%), Query Frame = 2 
Query:   92 ELPIFTAHAHVFTIDPKTKKTWIPSSSKAVEINYFFDPTKNCFRIVSIEDTSNGKQVIINSTLTEKMVFKKTSQKFGQWTDSKQCTIFGLGFNSEDDLDAFVEKFKSCIETMR 430
            E PIF+  AHVF IDP TKK W+P+S  AV ++YF+D T+N +RI+S+     G + IINST+T  M F KTSQKFGQW DS+  T++GLGF SE +L  F EKF+   E  R
Sbjct:    8 EQPIFSTRAHVFQIDPITKKNWLPASKHAVTVSYFYDATRNVYRIISV----GGTKAIINSTITPNMTFTKTSQKFGQWADSRANTVYGLGFASEQNLSQFAEKFQEVREAAR 116
[Close]
BLAST of WH1 domain-containing protein vs. Ensembl Xenopus
Match: rhag (Rh associated glycoprotein [Source:Xenbase;Acc:XB-GENE-983543])

HSP 1 Score: 138.272 bits (347), Expect = 4.796e-36
Identity = 61/113 (53.98%), Postives = 78/113 (69.03%), Query Frame = 2 
Query:   92 ELPIFTAHAHVFTIDPKTKKTWIPSSSKAVEINYFFDPTKNCFRIVSIEDTSNGKQVIINSTLTEKMVFKKTSQKFGQWTDSKQCTIFGLGFNSEDDLDAFVEKFKSCIETMR 430
            E PIF+  AHVF IDP TKK W+P+S  AV ++YF+D T+N +RI+S+     G + IINST+T  M F KTSQKFGQW DS+  T++GLGF SE +L  F EKF+   E  R
Sbjct:   10 EQPIFSTRAHVFQIDPITKKNWLPASKHAVTVSYFYDATRNVYRIISV----GGTKAIINSTITPNMTFTKTSQKFGQWADSRANTVYGLGFASEQNLSQFAEKFQEVREAAR 118
[Close]
BLAST of WH1 domain-containing protein vs. Ensembl Xenopus
Match: rhag (Rh associated glycoprotein [Source:Xenbase;Acc:XB-GENE-983543])

HSP 1 Score: 137.502 bits (345), Expect = 9.521e-36
Identity = 60/111 (54.05%), Postives = 77/111 (69.37%), Query Frame = 2 
Query:   98 PIFTAHAHVFTIDPKTKKTWIPSSSKAVEINYFFDPTKNCFRIVSIEDTSNGKQVIINSTLTEKMVFKKTSQKFGQWTDSKQCTIFGLGFNSEDDLDAFVEKFKSCIETMR 430
            PIF+  AHVF IDP TKK W+P+S  AV ++YF+D T+N +RI+S+     G + IINST+T  M F KTSQKFGQW DS+  T++GLGF SE +L  F EKF+   E  R
Sbjct:    6 PIFSTRAHVFQIDPITKKNWLPASKHAVTVSYFYDATRNVYRIISV----GGTKAIINSTITPNMTFTKTSQKFGQWADSRANTVYGLGFASEQNLSQFAEKFQEVREAAR 112
[Close]
BLAST of WH1 domain-containing protein vs. Ensembl Mouse
Match: Homer2 (homer scaffolding protein 2 [Source:MGI Symbol;Acc:MGI:1347354])

HSP 1 Score: 147.902 bits (372), Expect = 8.289e-40
Identity = 66/115 (57.39%), Postives = 83/115 (72.17%), Query Frame = 2 
Query:   86 MGELPIFTAHAHVFTIDPKTKKTWIPSSSKAVEINYFFDPTKNCFRIVSIEDTSNGKQVIINSTLTEKMVFKKTSQKFGQWTDSKQCTIFGLGFNSEDDLDAFVEKFKSCIETMR 430
            MGE PIFT  AHVF IDP TKK W+P+S +AV ++YF+D T+N +RI+S+    +G +VIINST+T  M F KTSQKFGQW DS+  T+FGLGF+SE  L  F EKF+   E  R
Sbjct:    1 MGEQPIFTTRAHVFQIDPSTKKNWVPASKQAVTVSYFYDVTRNSYRIISV----DGAKVIINSTITPNMTFTKTSQKFGQWADSRANTVFGLGFSSELQLTKFAEKFQEVREAAR 111
[Close]
BLAST of WH1 domain-containing protein vs. Ensembl Mouse
Match: Homer2 (homer scaffolding protein 2 [Source:MGI Symbol;Acc:MGI:1347354])

HSP 1 Score: 147.517 bits (371), Expect = 1.270e-39
Identity = 66/115 (57.39%), Postives = 83/115 (72.17%), Query Frame = 2 
Query:   86 MGELPIFTAHAHVFTIDPKTKKTWIPSSSKAVEINYFFDPTKNCFRIVSIEDTSNGKQVIINSTLTEKMVFKKTSQKFGQWTDSKQCTIFGLGFNSEDDLDAFVEKFKSCIETMR 430
            MGE PIFT  AHVF IDP TKK W+P+S +AV ++YF+D T+N +RI+S+    +G +VIINST+T  M F KTSQKFGQW DS+  T+FGLGF+SE  L  F EKF+   E  R
Sbjct:    1 MGEQPIFTTRAHVFQIDPSTKKNWVPASKQAVTVSYFYDVTRNSYRIISV----DGAKVIINSTITPNMTFTKTSQKFGQWADSRANTVFGLGFSSELQLTKFAEKFQEVREAAR 111
[Close]
BLAST of WH1 domain-containing protein vs. Ensembl Mouse
Match: Homer1 (homer scaffolding protein 1 [Source:MGI Symbol;Acc:MGI:1347345])

HSP 1 Score: 140.969 bits (354), Expect = 4.659e-39
Identity = 63/115 (54.78%), Postives = 81/115 (70.43%), Query Frame = 2 
Query:   86 MGELPIFTAHAHVFTIDPKTKKTWIPSSSKAVEINYFFDPTKNCFRIVSIEDTSNGKQVIINSTLTEKMVFKKTSQKFGQWTDSKQCTIFGLGFNSEDDLDAFVEKFKSCIETMR 430
            MGE PIF+  AHVF IDP TKK W+P+S  AV ++YF+D T+N +RI+S++    G + IINST+T  M F KTSQKFGQW DS+  T++GLGF+SE  L  F EKF+   E  R
Sbjct:    1 MGEQPIFSTRAHVFQIDPNTKKNWVPTSKHAVTVSYFYDSTRNVYRIISLD----GSKAIINSTITPNMTFTKTSQKFGQWADSRANTVYGLGFSSEHHLSKFAEKFQEFKEAAR 111
[Close]
BLAST of WH1 domain-containing protein vs. Ensembl Mouse
Match: Homer1 (homer scaffolding protein 1 [Source:MGI Symbol;Acc:MGI:1347345])

HSP 1 Score: 141.354 bits (355), Expect = 5.150e-39
Identity = 63/115 (54.78%), Postives = 81/115 (70.43%), Query Frame = 2 
Query:   86 MGELPIFTAHAHVFTIDPKTKKTWIPSSSKAVEINYFFDPTKNCFRIVSIEDTSNGKQVIINSTLTEKMVFKKTSQKFGQWTDSKQCTIFGLGFNSEDDLDAFVEKFKSCIETMR 430
            MGE PIF+  AHVF IDP TKK W+P+S  AV ++YF+D T+N +RI+S++    G + IINST+T  M F KTSQKFGQW DS+  T++GLGF+SE  L  F EKF+   E  R
Sbjct:    1 MGEQPIFSTRAHVFQIDPNTKKNWVPTSKHAVTVSYFYDSTRNVYRIISLD----GSKAIINSTITPNMTFTKTSQKFGQWADSRANTVYGLGFSSEHHLSKFAEKFQEFKEAAR 111
[Close]
BLAST of WH1 domain-containing protein vs. Ensembl Mouse
Match: Homer1 (homer scaffolding protein 1 [Source:MGI Symbol;Acc:MGI:1347345])

HSP 1 Score: 139.813 bits (351), Expect = 1.425e-38
Identity = 63/115 (54.78%), Postives = 81/115 (70.43%), Query Frame = 2 
Query:   86 MGELPIFTAHAHVFTIDPKTKKTWIPSSSKAVEINYFFDPTKNCFRIVSIEDTSNGKQVIINSTLTEKMVFKKTSQKFGQWTDSKQCTIFGLGFNSEDDLDAFVEKFKSCIETMR 430
            MGE PIF+  AHVF IDP TKK W+P+S  AV ++YF+D T+N +RI+S++    G + IINST+T  M F KTSQKFGQW DS+  T++GLGF+SE  L  F EKF+   E  R
Sbjct:    1 MGEQPIFSTRAHVFQIDPNTKKNWVPTSKHAVTVSYFYDSTRNVYRIISLD----GSKAIINSTITPNMTFTKTSQKFGQWADSRANTVYGLGFSSEHHLSKFAEKFQEFKEAAR 111
[Close]
BLAST of WH1 domain-containing protein vs. UniProt/SwissProt
Match: sp|O88801|HOME2_RAT (Homer protein homolog 2 OS=Rattus norvegicus OX=10116 GN=Homer2 PE=1 SV=1)

HSP 1 Score: 149.058 bits (375), Expect = 2.979e-39
Identity = 66/115 (57.39%), Postives = 83/115 (72.17%), Query Frame = 2 
Query:   86 MGELPIFTAHAHVFTIDPKTKKTWIPSSSKAVEINYFFDPTKNCFRIVSIEDTSNGKQVIINSTLTEKMVFKKTSQKFGQWTDSKQCTIFGLGFNSEDDLDAFVEKFKSCIETMR 430
            MGE PIFT  AHVF IDP TKK W+P+S +AV ++YF+D T+N +RI+S+    +G +VIINST+T  M F KTSQKFGQW DS+  T+FGLGF+SE  L  F EKF+   E  R
Sbjct:    1 MGEQPIFTTRAHVFQIDPSTKKNWVPASKQAVTVSYFYDVTRNSYRIISV----DGAKVIINSTITPNMTFTKTSQKFGQWADSRANTVFGLGFSSEQQLTKFAEKFQEVREAAR 111
[Close]
BLAST of WH1 domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9QWW1|HOME2_MOUSE (Homer protein homolog 2 OS=Mus musculus OX=10090 GN=Homer2 PE=1 SV=1)

HSP 1 Score: 147.517 bits (371), Expect = 8.881e-39
Identity = 66/115 (57.39%), Postives = 83/115 (72.17%), Query Frame = 2 
Query:   86 MGELPIFTAHAHVFTIDPKTKKTWIPSSSKAVEINYFFDPTKNCFRIVSIEDTSNGKQVIINSTLTEKMVFKKTSQKFGQWTDSKQCTIFGLGFNSEDDLDAFVEKFKSCIETMR 430
            MGE PIFT  AHVF IDP TKK W+P+S +AV ++YF+D T+N +RI+S+    +G +VIINST+T  M F KTSQKFGQW DS+  T+FGLGF+SE  L  F EKF+   E  R
Sbjct:    1 MGEQPIFTTRAHVFQIDPSTKKNWVPASKQAVTVSYFYDVTRNSYRIISV----DGAKVIINSTITPNMTFTKTSQKFGQWADSRANTVFGLGFSSELQLTKFAEKFQEVREAAR 111
[Close]
BLAST of WH1 domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9NSB8|HOME2_HUMAN (Homer protein homolog 2 OS=Homo sapiens OX=9606 GN=HOMER2 PE=1 SV=1)

HSP 1 Score: 146.747 bits (369), Expect = 1.927e-38
Identity = 65/115 (56.52%), Postives = 83/115 (72.17%), Query Frame = 2 
Query:   86 MGELPIFTAHAHVFTIDPKTKKTWIPSSSKAVEINYFFDPTKNCFRIVSIEDTSNGKQVIINSTLTEKMVFKKTSQKFGQWTDSKQCTIFGLGFNSEDDLDAFVEKFKSCIETMR 430
            MGE PIFT  AHVF IDP TKK W+P+S +AV ++YF+D T+N +RI+S+    +G +VIINST+T  M F KTSQKFGQW DS+  T+FGLGF+SE  L  F EKF+   E  +
Sbjct:    1 MGEQPIFTTRAHVFQIDPNTKKNWMPASKQAVTVSYFYDVTRNSYRIISV----DGAKVIINSTITPNMTFTKTSQKFGQWADSRANTVFGLGFSSEQQLTKFAEKFQEVKEAAK 111
[Close]
BLAST of WH1 domain-containing protein vs. UniProt/SwissProt
Match: sp|Q2KJ56|HOME1_BOVIN (Homer protein homolog 1 OS=Bos taurus OX=9913 GN=HOMER1 PE=2 SV=1)

HSP 1 Score: 144.05 bits (362), Expect = 2.194e-37
Identity = 63/115 (54.78%), Postives = 81/115 (70.43%), Query Frame = 2 
Query:   86 MGELPIFTAHAHVFTIDPKTKKTWIPSSSKAVEINYFFDPTKNCFRIVSIEDTSNGKQVIINSTLTEKMVFKKTSQKFGQWTDSKQCTIFGLGFNSEDDLDAFVEKFKSCIETMR 430
            MGE PIF+  AHVF IDP TKK W+P+S  AV ++YF+D T+N +RI+S+    +G + IINST+T  M F KTSQKFGQW DS+  T++GLGF+SE  L  F EKF+   E  R
Sbjct:    1 MGEQPIFSTRAHVFQIDPNTKKNWVPTSKHAVTVSYFYDSTRNVYRIISL----DGSKAIINSTITPNMTFTKTSQKFGQWADSRANTVYGLGFSSEHHLSKFAEKFQEFKEAAR 111
[Close]
BLAST of WH1 domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9Z214|HOME1_RAT (Homer protein homolog 1 OS=Rattus norvegicus OX=10116 GN=Homer1 PE=1 SV=2)

HSP 1 Score: 144.05 bits (362), Expect = 2.497e-37
Identity = 63/115 (54.78%), Postives = 81/115 (70.43%), Query Frame = 2 
Query:   86 MGELPIFTAHAHVFTIDPKTKKTWIPSSSKAVEINYFFDPTKNCFRIVSIEDTSNGKQVIINSTLTEKMVFKKTSQKFGQWTDSKQCTIFGLGFNSEDDLDAFVEKFKSCIETMR 430
            MGE PIF+  AHVF IDP TKK W+P+S  AV ++YF+D T+N +RI+S+    +G + IINST+T  M F KTSQKFGQW DS+  T++GLGF+SE  L  F EKF+   E  R
Sbjct:    1 MGEQPIFSTRAHVFQIDPNTKKNWVPTSKHAVTVSYFYDSTRNVYRIISL----DGSKAIINSTITPNMTFTKTSQKFGQWADSRANTVYGLGFSSEHHLSKFAEKFQEFKEAAR 111
[Close]
BLAST of WH1 domain-containing protein vs. TrEMBL
Match: Q5C3H4 (SJCHGC07300 protein (Fragment) OS=Schistosoma japonicum OX=6182 PE=2 SV=2)

HSP 1 Score: 180.259 bits (456), Expect = 1.328e-50
Identity = 78/123 (63.41%), Postives = 102/123 (82.93%), Query Frame = 2 
Query:   86 MGELPIFTAHAHVFTIDPKTKKTWIPSSSKAVEINYFFDPTKNCFRIVSIEDTSNGKQVIINSTLTEKMVFKKTSQKFGQWTDSKQCTIFGLGFNSEDDLDAFVEKFKSCIETMRNKSAPNHN 454
            MGELPIFT  AHVFTI+P+TKK+WIPSSSKAV++N+F+D  K+C+RI+S+ED+S  K+VIINS LTEKM FKKTSQKFGQW DS+   + GLGF+SE DL  F+ +FK C+++M+N++ P  N
Sbjct:    7 MGELPIFTCQAHVFTINPQTKKSWIPSSSKAVDVNFFYDSNKHCYRIISVEDSSGSKKVIINSMLTEKMTFKKTSQKFGQWADSRTGGVHGLGFSSEADLTMFINQFKQCVDSMKNQTHPESN 129
[Close]
BLAST of WH1 domain-containing protein vs. TrEMBL
Match: A0A3Q0KDV8 (Putative homer OS=Schistosoma mansoni OX=6183 PE=4 SV=1)

HSP 1 Score: 183.341 bits (464), Expect = 2.664e-49
Identity = 80/123 (65.04%), Postives = 101/123 (82.11%), Query Frame = 2 
Query:   86 MGELPIFTAHAHVFTIDPKTKKTWIPSSSKAVEINYFFDPTKNCFRIVSIEDTSNGKQVIINSTLTEKMVFKKTSQKFGQWTDSKQCTIFGLGFNSEDDLDAFVEKFKSCIETMRNKSAPNHN 454
            MGELPIFT  AHVFTI+P+TKK+WIPSSSKAV++N+F+D  K+C+RI+S+ED+S  K+VIINSTLTEKM FKKTSQKFGQW DSK   + GLGF+SE DL  FV +FK C+++M+ +  P  N
Sbjct:    1 MGELPIFTCQAHVFTINPQTKKSWIPSSSKAVDVNFFYDSNKHCYRIISVEDSSGSKKVIINSTLTEKMTFKKTSQKFGQWADSKTGGVHGLGFSSEADLTMFVNQFKQCVDSMKTQIQPESN 123
[Close]
BLAST of WH1 domain-containing protein vs. TrEMBL
Match: C1L4V2 (Homer protein OS=Schistosoma japonicum OX=6182 GN=EWB00_009798 PE=2 SV=1)

HSP 1 Score: 183.341 bits (464), Expect = 2.835e-49
Identity = 78/123 (63.41%), Postives = 102/123 (82.93%), Query Frame = 2 
Query:   86 MGELPIFTAHAHVFTIDPKTKKTWIPSSSKAVEINYFFDPTKNCFRIVSIEDTSNGKQVIINSTLTEKMVFKKTSQKFGQWTDSKQCTIFGLGFNSEDDLDAFVEKFKSCIETMRNKSAPNHN 454
            MGELPIFT  AHVFTI+P+TKK+WIPSSSKAV++N+F+D  K+C+RI+S+ED+S  K+VIINS LTEKM FKKTSQKFGQW DS+   + GLGF+SE DL  F+ +FK C+++M+N++ P  N
Sbjct:    2 MGELPIFTCQAHVFTINPQTKKSWIPSSSKAVDVNFFYDSNKHCYRIISVEDSSGSKKVIINSMLTEKMTFKKTSQKFGQWADSRTGGVHGLGFSSEADLTMFINQFKQCVDSMKNQTHPESN 124
[Close]
BLAST of WH1 domain-containing protein vs. TrEMBL
Match: A0A3P8EIJ0 (WH1 domain-containing protein OS=Schistosoma mattheei OX=31246 GN=SMTD_LOCUS8795 PE=4 SV=1)

HSP 1 Score: 173.711 bits (439), Expect = 1.172e-48
Identity = 77/121 (63.64%), Postives = 99/121 (81.82%), Query Frame = 2 
Query:   92 ELPIFTAHAHVFTIDPKTKKTWIPSSSKAVEINYFFDPTKNCFRIVSIEDTSNGKQVIINSTLTEKMVFKKTSQKFGQWTDSKQCTIFGLGFNSEDDLDAFVEKFKSCIETMRNKSAPNHN 454
            ELPIFT  AHVFTI+P+TKK+WIPSSSKAV++N+F+D  K+C+RI+S+ED+S  K+VIINSTLTEKM FKKTSQKFGQW DSK   + GLGF+SE DL  F+ +FK C+++M+ +  P  N
Sbjct:   10 ELPIFTCQAHVFTINPQTKKSWIPSSSKAVDVNFFYDSNKHCYRIISVEDSSGSKKVIINSTLTEKMTFKKTSQKFGQWADSKTGGVHGLGFSSEADLTMFINQFKQCVDSMKTQIQPEAN 130
[Close]
BLAST of WH1 domain-containing protein vs. TrEMBL
Match: A0A183P359 (WH1 domain-containing protein OS=Schistosoma mattheei OX=31246 PE=4 SV=1)

HSP 1 Score: 173.711 bits (439), Expect = 1.374e-48
Identity = 77/121 (63.64%), Postives = 99/121 (81.82%), Query Frame = 2 
Query:   92 ELPIFTAHAHVFTIDPKTKKTWIPSSSKAVEINYFFDPTKNCFRIVSIEDTSNGKQVIINSTLTEKMVFKKTSQKFGQWTDSKQCTIFGLGFNSEDDLDAFVEKFKSCIETMRNKSAPNHN 454
            ELPIFT  AHVFTI+P+TKK+WIPSSSKAV++N+F+D  K+C+RI+S+ED+S  K+VIINSTLTEKM FKKTSQKFGQW DSK   + GLGF+SE DL  F+ +FK C+++M+ +  P  N
Sbjct:   10 ELPIFTCQAHVFTINPQTKKSWIPSSSKAVDVNFFYDSNKHCYRIISVEDSSGSKKVIINSTLTEKMTFKKTSQKFGQWADSKTGGVHGLGFSSEADLTMFINQFKQCVDSMKTQIQPEAN 130
[Close]
BLAST of WH1 domain-containing protein vs. Ensembl Cavefish
Match: homer2 (homer scaffold protein 2 [Source:NCBI gene;Acc:111197564])

HSP 1 Score: 152.525 bits (384), Expect = 1.541e-41
Identity = 91/223 (40.81%), Postives = 130/223 (58.30%), Query Frame = 2 
Query:   86 MGELPIFTAHAHVFTIDPKTKKTWIPSSSKAVEINYFFDPTKNCFRIVSIEDTSNGKQVIINSTLTEKMVFKKTSQKFGQWTDSKQCTIFGLGFNSEDDLDAFVEKFKSCIET---MRNKSAPNHNDNANNKEVNKREL-LGLNNNVVGISSSGRQWXXXXXXXXXXXXXXKVLSLEVELERLNKKMEEMKIQH-QEEIKRLKDELDHTNTGALANTVDNYKT 739
            MGE PIFT  AHVF IDP TKK W+P+S +AV ++YF+D T+N +RI+S+    +G +VIINST+T  M F KTSQKFGQW DS+  T+FGLGF SE  L  F EKF+   E     R+KS    + ++N+ + + RE  +  +N V  ++ +  +  + T  +  L      L   +E    N K  E ++Q  +E   RL D L   N+     +V+N+KT
Sbjct:    1 MGEQPIFTTRAHVFQIDPTTKKNWVPASKQAVTVSYFYDSTRNSYRIISV----DGSKVIINSTITPNMTFTKTSQKFGQWADSRANTVFGLGFASEQQLSKFAEKFQEVKEAAKLARDKSQETTDTSSNHSQGSGRETPVQSSNQVSSMNGTDDEKISHTPETTALQTENDRLKTAIEQSNSNAKKFETELQTLRESNARLLDALQEANS-----SVENWKT 214
[Close]
BLAST of WH1 domain-containing protein vs. Ensembl Cavefish
Match: homer2 (homer scaffold protein 2 [Source:NCBI gene;Acc:111197564])

HSP 1 Score: 147.132 bits (370), Expect = 1.857e-39
Identity = 89/221 (40.27%), Postives = 128/221 (57.92%), Query Frame = 2 
Query:   92 ELPIFTAHAHVFTIDPKTKKTWIPSSSKAVEINYFFDPTKNCFRIVSIEDTSNGKQVIINSTLTEKMVFKKTSQKFGQWTDSKQCTIFGLGFNSEDDLDAFVEKFKSCIET---MRNKSAPNHNDNANNKEVNKREL-LGLNNNVVGISSSGRQWXXXXXXXXXXXXXXKVLSLEVELERLNKKMEEMKIQH-QEEIKRLKDELDHTNTGALANTVDNYKT 739
            E PIFT  AHVF IDP TKK W+P+S +AV ++YF+D T+N +RI+S+    +G +VIINST+T  M F KTSQKFGQW DS+  T+FGLGF SE  L  F EKF+   E     R+KS    + ++N+ + + RE  +  +N V  ++ +  +  + T  +  L      L   +E    N K  E ++Q  +E   RL D L   N+     +V+N+KT
Sbjct:    2 EQPIFTTRAHVFQIDPTTKKNWVPASKQAVTVSYFYDSTRNSYRIISV----DGSKVIINSTITPNMTFTKTSQKFGQWADSRANTVFGLGFASEQQLSKFAEKFQEVKEAAKLARDKSQETTDTSSNHSQGSGRETPVQSSNQVSSMNGTDDEKISHTPETTALQTENDRLKTAIEQSNSNAKKFETELQTLRESNARLLDALQEANS-----SVENWKT 213
[Close]
BLAST of WH1 domain-containing protein vs. Ensembl Cavefish
Match: HOMER1 (homer scaffold protein 1 [Source:NCBI gene;Acc:103035651])

HSP 1 Score: 144.821 bits (364), Expect = 1.405e-38
Identity = 63/115 (54.78%), Postives = 80/115 (69.57%), Query Frame = 2 
Query:   86 MGELPIFTAHAHVFTIDPKTKKTWIPSSSKAVEINYFFDPTKNCFRIVSIEDTSNGKQVIINSTLTEKMVFKKTSQKFGQWTDSKQCTIFGLGFNSEDDLDAFVEKFKSCIETMR 430
            MGE PIF+  AHVF IDP TKK W+P+S  AV ++YF+D T+N +RI+S+    +G + IINST+T  M F KTSQKFGQW DS+  T++GLGF+SE  L  F EKF    E  R
Sbjct:    1 MGEQPIFSTRAHVFQIDPNTKKNWVPTSKHAVTVSYFYDSTRNVYRIISL----DGSKAIINSTITPNMTFTKTSQKFGQWADSRANTVYGLGFSSESQLSKFAEKFAEFKEAAR 111
[Close]
BLAST of WH1 domain-containing protein vs. Ensembl Cavefish
Match: HOMER1 (homer scaffold protein 1 [Source:NCBI gene;Acc:103035651])

HSP 1 Score: 144.821 bits (364), Expect = 1.525e-38
Identity = 63/115 (54.78%), Postives = 80/115 (69.57%), Query Frame = 2 
Query:   86 MGELPIFTAHAHVFTIDPKTKKTWIPSSSKAVEINYFFDPTKNCFRIVSIEDTSNGKQVIINSTLTEKMVFKKTSQKFGQWTDSKQCTIFGLGFNSEDDLDAFVEKFKSCIETMR 430
            MGE PIF+  AHVF IDP TKK W+P+S  AV ++YF+D T+N +RI+S+    +G + IINST+T  M F KTSQKFGQW DS+  T++GLGF+SE  L  F EKF    E  R
Sbjct:    1 MGEQPIFSTRAHVFQIDPNTKKNWVPTSKHAVTVSYFYDSTRNVYRIISL----DGSKAIINSTITPNMTFTKTSQKFGQWADSRANTVYGLGFSSESQLSKFAEKFAEFKEAAR 111
[Close]
BLAST of WH1 domain-containing protein vs. Ensembl Cavefish
Match: HOMER1 (homer scaffold protein 1 [Source:NCBI gene;Acc:103035651])

HSP 1 Score: 139.043 bits (349), Expect = 2.017e-36
Identity = 61/115 (53.04%), Postives = 79/115 (68.70%), Query Frame = 2 
Query:   86 MGELPIFTAHAHVFTIDPKTKKTWIPSSSKAVEINYFFDPTKNCFRIVSIEDTSNGKQVIINSTLTEKMVFKKTSQKFGQWTDSKQCTIFGLGFNSEDDLDAFVEKFKSCIETMR 430
            + E PIF+  AHVF IDP TKK W+P+S  AV ++YF+D T+N +RI+S+    +G + IINST+T  M F KTSQKFGQW DS+  T++GLGF+SE  L  F EKF    E  R
Sbjct:   16 LREQPIFSTRAHVFQIDPNTKKNWVPTSKHAVTVSYFYDSTRNVYRIISL----DGSKAIINSTITPNMTFTKTSQKFGQWADSRANTVYGLGFSSESQLSKFAEKFAEFKEAAR 126
[Close]
BLAST of WH1 domain-containing protein vs. Ensembl Sea Lamprey
Match: homer3a (homer scaffold protein 3a [Source:ZFIN;Acc:ZDB-GENE-170413-3])

HSP 1 Score: 118.242 bits (295), Expect = 3.636e-32
Identity = 56/125 (44.80%), Postives = 78/125 (62.40%), Query Frame = 2 
Query:   92 ELPIFTAHAHVFTIDPKTKKTWIPSSSKAVEINYFFDPTKNCFRIVSIEDTSNGKQVIINSTLTEKMVFKKTSQKFGQWTDSKQCTIFGLGFNSEDDLDAFVEKFKSCIETMRNKSAPNHNDNAN 466
            E P+F++ A VF IDP T+++W+P S + V ++++ D  +N  RI+SI+    G +VIINST+   M F KTSQKFGQW D K  T++GLGFNSE  L  F +KF+   E    K  P  +   N
Sbjct:    6 EQPVFSSEAQVFQIDPTTQRSWLPVSQQVVRVSFYHDAVRNIHRIISID----GTKVIINSTILPNMKFTKTSQKFGQWADGKANTVYGLGFNSEKLLMEFSQKFEEIKEGSAGKQQPMQDGGGN 126
[Close]
BLAST of WH1 domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006730.1 (pep scaffold:Pmarinus_7.0:GL476423:313891:330988:1 gene:ENSPMAG00000006060.1 transcript:ENSPMAT00000006730.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 58.151 bits (139), Expect = 2.227e-9
Identity = 32/116 (27.59%), Postives = 60/116 (51.72%), Query Frame = 2 
Query:   92 ELPIFTAHAHVFTIDPKTKKTWIPSSSKA--VEINYFFDPTKNCFRIVS--IEDTSNGKQVIINSTLTEKMVFKKTSQKFGQWTDSKQCTIFGLGFNSEDDLDAFVEKFKSCIETM 427
            E  I  A A V   D   KK W+PS  +     ++ +   + N FR+V   ++D    +QV+IN +L++ + + + +  F QW D++Q  ++GL F S++D + F       ++ +
Sbjct:    3 EQSICQARAQVMVYDDANKK-WLPSGGQQGFSRVHIYHHTSLNTFRVVGRRMQD----QQVVINCSLSKGLKYNQATPMFHQWRDARQ--VYGLNFGSKEDANVFANGIMHALDAL 111
[Close]
BLAST of WH1 domain-containing protein vs. Ensembl Nematostella
Match: EDO45622 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RSE6])

HSP 1 Score: 127.872 bits (320), Expect = 6.105e-33
Identity = 56/108 (51.85%), Postives = 76/108 (70.37%), Query Frame = 2 
Query:   92 ELPIFTAHAHVFTIDPKTKKTWIPSSSKAVEINYFFDPTKNCFRIVSIEDTSNGKQVIINSTLTEKMVFKKTSQKFGQWTDSKQCTIFGLGFNSEDDLDAFVEKFKSC 415
            E P+F+  AHVF IDP+TKK+WIP S +AV +++++DP     RI+S++    G + IINST+   M F KTSQKFGQW+D K  ++FGLGF SE +L+ F EKFK  
Sbjct:   13 EQPVFSTRAHVFQIDPQTKKSWIPCSKQAVTVSFYYDPINETHRIISVD----GSKAIINSTIFPNMNFTKTSQKFGQWSDPKVSSVFGLGFPSEAELNKFAEKFKEA 116
[Close]
BLAST of WH1 domain-containing protein vs. Ensembl Nematostella
Match: EDO41208 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4T4])

HSP 1 Score: 61.6178 bits (148), Expect = 1.218e-11
Identity = 35/123 (28.46%), Postives = 62/123 (50.41%), Query Frame = 2 
Query:   86 MGELPIFTAHAHVFTIDPKTKKTWIPS--SSKAVEINYFFDPTKNCFRIVSIEDTSNGKQVIINSTLTEKMVFKKTSQKFGQWTDSKQCTIFGLGFNSEDDLDAFVEKFKSCIETMRNKSAPN 448
            + E  I  A A V   + + K+ W PS  S     ++ +  P  N FRIV  +   +   V+IN  L + + + + +  F QW D +Q  ++GL F S+D+ D F +  +  +ET++  + P+
Sbjct:    1 LSEHSIAQARASVMLYNNEAKQ-WAPSGGSQGISRVHVYHHPVNNTFRIVGRKMADHA--VVINCALAKGLKYNEATPTFHQWRDQRQ--VYGLNFQSKDEADLFGQAVRDALETLKTSAPPS 118
[Close]
BLAST of WH1 domain-containing protein vs. Ensembl Medaka
Match: homer2 (homer scaffold protein 2 [Source:NCBI gene;Acc:101156722])

HSP 1 Score: 142.895 bits (359), Expect = 5.298e-38
Identity = 68/138 (49.28%), Postives = 92/138 (66.67%), Query Frame = 2 
Query:   86 MGELPIFTAHAHVFTIDPKTKKTWIPSSSKAVEINYFFDPTKNCFRIVSIEDTSNGKQVIINSTLTEKMVFKKTSQKFGQWTDSKQCTIFGLGFNSEDDLDAFVEKF---KSCIETMRNKSAPNHNDNANNKEVNKRE 490
            MGE PI+T  AHVF IDP TKK W+P+S ++V ++YF+D ++N +RI+S+    +G +VIINST+T  M F KTSQKFGQW DS+  T+FGLGF SE  L  F EKF   K   +  R+KS       +N+ + + RE
Sbjct:    1 MGEQPIYTTRAHVFQIDPSTKKNWVPASRQSVTVSYFYDSSRNSYRIISV----DGTKVIINSTITPNMTFTKTSQKFGQWADSRANTVFGLGFASEQLLSKFAEKFQEVKDAAKLARDKSQEKGETLSNHSQESGRE 134
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BLAST of WH1 domain-containing protein vs. Ensembl Medaka
Match: HOMER1 (homer scaffold protein 1 [Source:NCBI gene;Acc:101170111])

HSP 1 Score: 142.51 bits (358), Expect = 8.992e-38
Identity = 63/115 (54.78%), Postives = 79/115 (68.70%), Query Frame = 2 
Query:   86 MGELPIFTAHAHVFTIDPKTKKTWIPSSSKAVEINYFFDPTKNCFRIVSIEDTSNGKQVIINSTLTEKMVFKKTSQKFGQWTDSKQCTIFGLGFNSEDDLDAFVEKFKSCIETMR 430
            MGE PIF+  AHVF IDP TKK W+P+S  AV ++YFFD T+N +RI+S+    +G + IINST+T  M F KTSQKFGQW DS+  T++GLGF+ E  L  F EKF    E  R
Sbjct:    1 MGEQPIFSTRAHVFQIDPNTKKNWVPTSKHAVTVSYFFDSTRNVYRIISL----DGSKAIINSTITPNMTFTKTSQKFGQWADSRANTVYGLGFSCESHLAKFAEKFAEFKEAAR 111
[Close]
BLAST of WH1 domain-containing protein vs. Ensembl Medaka
Match: HOMER1 (homer scaffold protein 1 [Source:NCBI gene;Acc:101170111])

HSP 1 Score: 141.739 bits (356), Expect = 2.024e-37
Identity = 63/115 (54.78%), Postives = 79/115 (68.70%), Query Frame = 2 
Query:   86 MGELPIFTAHAHVFTIDPKTKKTWIPSSSKAVEINYFFDPTKNCFRIVSIEDTSNGKQVIINSTLTEKMVFKKTSQKFGQWTDSKQCTIFGLGFNSEDDLDAFVEKFKSCIETMR 430
            MGE PIF+  AHVF IDP TKK W+P+S  AV ++YFFD T+N +RI+S+    +G + IINST+T  M F KTSQKFGQW DS+  T++GLGF+ E  L  F EKF    E  R
Sbjct:    1 MGEQPIFSTRAHVFQIDPNTKKNWVPTSKHAVTVSYFFDSTRNVYRIISL----DGSKAIINSTITPNMTFTKTSQKFGQWADSRANTVYGLGFSCESHLAKFAEKFAEFKEAAR 111
[Close]
BLAST of WH1 domain-containing protein vs. Ensembl Medaka
Match: homer3b (homer scaffold protein 3 [Source:NCBI gene;Acc:101164469])

HSP 1 Score: 139.043 bits (349), Expect = 1.578e-36
Identity = 58/115 (50.43%), Postives = 80/115 (69.57%), Query Frame = 2 
Query:   86 MGELPIFTAHAHVFTIDPKTKKTWIPSSSKAVEINYFFDPTKNCFRIVSIEDTSNGKQVIINSTLTEKMVFKKTSQKFGQWTDSKQCTIFGLGFNSEDDLDAFVEKFKSCIETMR 430
            MGE PIF+A AHVF IDP TK+ W+P+S  AV +++F+D  ++ +RI+S+     G + +INST+T  M F KTSQKFGQW DS+  T++GLGF++E  L  F E+FK   E  R
Sbjct:    1 MGEQPIFSARAHVFQIDPATKRNWLPASKHAVTVSFFYDANRSVYRIISV----GGTKAVINSTITPNMTFTKTSQKFGQWADSRANTVYGLGFSTEQQLQQFAEQFKEIKEAAR 111
[Close]
BLAST of WH1 domain-containing protein vs. Ensembl Medaka
Match: homer1b (homer protein homolog 1-like [Source:NCBI gene;Acc:101163175])

HSP 1 Score: 138.658 bits (348), Expect = 2.364e-36
Identity = 60/115 (52.17%), Postives = 80/115 (69.57%), Query Frame = 2 
Query:   86 MGELPIFTAHAHVFTIDPKTKKTWIPSSSKAVEINYFFDPTKNCFRIVSIEDTSNGKQVIINSTLTEKMVFKKTSQKFGQWTDSKQCTIFGLGFNSEDDLDAFVEKFKSCIETMR 430
            MGE PI++  AHVF IDP TKK W+P+S  AV ++YF+D T+N +RI+S+    +G + IINST++  M F KTSQKFGQW DS+  T++GLGF++E  L  F EKF    E  R
Sbjct:    1 MGEQPIYSTRAHVFQIDPNTKKNWLPTSKHAVTVSYFYDSTRNVYRIISL----DGTKAIINSTISPNMTFTKTSQKFGQWADSRANTVYGLGFSTEHHLSKFAEKFAEYKEAAR 111
[Close]
BLAST of WH1 domain-containing protein vs. Planmine SMEST
Match: SMESG000035255.1 (SMESG000035255.1)

HSP 1 Score: 538.11 bits (1385), Expect = 0.000e+0
Identity = 298/298 (100.00%), Postives = 298/298 (100.00%), Query Frame = 2 
Query:   86 MGELPIFTAHAHVFTIDPKTKKTWIPSSSKAVEINYFFDPTKNCFRIVSIEDTSNGKQVIINSTLTEKMVFKKTSQKFGQWTDSKQCTIFGLGFNSEDDLDAFVEKFKSCIETMRNKSAPNHNDNANNKEVNKRELLGLNNNVVGISSSGRQWXXXXXXXXXXXXXXKVLSLEVELERLNKKMEEMKIQHQEEIKRLKDELDHTNTGALANTVDNYKTTKDMKFRVAXXXXXXXXXXXXXXXXXXXXTFSQISSLLTVHQQMESTVKQLSNYHYLIGQKLSDIVTSQPSDVKPPIAYG 979
            MGELPIFTAHAHVFTIDPKTKKTWIPSSSKAVEINYFFDPTKNCFRIVSIEDTSNGKQVIINSTLTEKMVFKKTSQKFGQWTDSKQCTIFGLGFNSEDDLDAFVEKFKSCIETMRNKSAPNHNDNANNKEVNKRELLGLNNNVVGISSSGRQWSNLTSTSPNLNNNPKVLSLEVELERLNKKMEEMKIQHQEEIKRLKDELDHTNTGALANTVDNYKTTKDMKFRVAELENENKELKRKLKESNESKTFSQISSLLTVHQQMESTVKQLSNYHYLIGQKLSDIVTSQPSDVKPPIAYG
Sbjct:    1 MGELPIFTAHAHVFTIDPKTKKTWIPSSSKAVEINYFFDPTKNCFRIVSIEDTSNGKQVIINSTLTEKMVFKKTSQKFGQWTDSKQCTIFGLGFNSEDDLDAFVEKFKSCIETMRNKSAPNHNDNANNKEVNKRELLGLNNNVVGISSSGRQWSNLTSTSPNLNNNPKVLSLEVELERLNKKMEEMKIQHQEEIKRLKDELDHTNTGALANTVDNYKTTKDMKFRVAELENENKELKRKLKESNESKTFSQISSLLTVHQQMESTVKQLSNYHYLIGQKLSDIVTSQPSDVKPPIAYG 298
[Close]
BLAST of WH1 domain-containing protein vs. Planmine SMEST
Match: SMESG000063850.1 (SMESG000063850.1)

HSP 1 Score: 50.0618 bits (118), Expect = 2.461e-6
Identity = 30/116 (25.86%), Postives = 55/116 (47.41%), Query Frame = 2 
Query:   86 MGELPIFTAHAHVFTIDPKTKKTWIPSSSKA--VEINYFFDPTKNCFRIVSIEDTSNGKQVIINSTLTEKMVFKKTSQKFGQWTDSKQCTIFGLGFNSEDDLDAFVEKFKSCIETM 427
            M E P+ TA A V   D  T  +W+ S S     ++  F     N +R+V  +   N K+V++N  +   + + +    F QW D+K   ++GL F ++++ + F       +E +
Sbjct:    1 MDEKPVATARASVMLFDAVTN-SWVASGSTQGISKVQLFRHQLNNTYRVVGWK--LNDKEVVLNCAIFRGLKYNQARPTFHQWRDTKH-QVYGLNFTNKEEAEQFAAAILEALENL 112
The following BLAST results are available for this feature:
BLAST of WH1 domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
HOMER13.819e-3954.78homer scaffold protein 1 [Source:HGNC Symbol;Acc:H... [more]
HOMER24.014e-3956.52homer scaffold protein 2 [Source:HGNC Symbol;Acc:H... [more]
HOMER24.113e-3956.52homer scaffold protein 2 [Source:HGNC Symbol;Acc:H... [more]
HOMER17.908e-3854.78homer scaffold protein 1 [Source:HGNC Symbol;Acc:H... [more]
HOMER35.783e-3753.10homer scaffold protein 3 [Source:HGNC Symbol;Acc:H... [more]
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BLAST of WH1 domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of WH1 domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
homer1.767e-3847.06gene:FBgn0025777 transcript:FBtr0079306[more]
homer1.767e-3847.06gene:FBgn0025777 transcript:FBtr0329892[more]
homer7.390e-3847.06gene:FBgn0025777 transcript:FBtr0329893[more]
homer5.670e-3745.75gene:FBgn0025777 transcript:FBtr0333346[more]
homer6.430e-3745.75gene:FBgn0025777 transcript:FBtr0332330[more]
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BLAST of WH1 domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
homer1b1.818e-3653.04homer scaffold protein 1b [Source:ZFIN;Acc:ZDB-GEN... [more]
homer3b4.662e-3550.43homer scaffold protein 3b [Source:ZFIN;Acc:ZDB-GEN... [more]
homer3b5.213e-3550.43homer scaffold protein 3b [Source:ZFIN;Acc:ZDB-GEN... [more]
homer1b4.786e-3452.21homer scaffold protein 1b [Source:ZFIN;Acc:ZDB-GEN... [more]
homer3a1.106e-3048.15homer scaffold protein 3a [Source:ZFIN;Acc:ZDB-GEN... [more]
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BLAST of WH1 domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ldhb2.181e-3849.28lactate dehydrogenase B [Source:Xenbase;Acc:XB-GEN... [more]
homer13.123e-3753.91prolactin-releasing peptide receptor-like [Source:... [more]
rhag3.999e-3653.98Rh associated glycoprotein [Source:Xenbase;Acc:XB-... [more]
rhag4.796e-3653.98Rh associated glycoprotein [Source:Xenbase;Acc:XB-... [more]
rhag9.521e-3654.05Rh associated glycoprotein [Source:Xenbase;Acc:XB-... [more]
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BLAST of WH1 domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Homer28.289e-4057.39homer scaffolding protein 2 [Source:MGI Symbol;Acc... [more]
Homer21.270e-3957.39homer scaffolding protein 2 [Source:MGI Symbol;Acc... [more]
Homer14.659e-3954.78homer scaffolding protein 1 [Source:MGI Symbol;Acc... [more]
Homer15.150e-3954.78homer scaffolding protein 1 [Source:MGI Symbol;Acc... [more]
Homer11.425e-3854.78homer scaffolding protein 1 [Source:MGI Symbol;Acc... [more]
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BLAST of WH1 domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|O88801|HOME2_RAT2.979e-3957.39Homer protein homolog 2 OS=Rattus norvegicus OX=10... [more]
sp|Q9QWW1|HOME2_MOUSE8.881e-3957.39Homer protein homolog 2 OS=Mus musculus OX=10090 G... [more]
sp|Q9NSB8|HOME2_HUMAN1.927e-3856.52Homer protein homolog 2 OS=Homo sapiens OX=9606 GN... [more]
sp|Q2KJ56|HOME1_BOVIN2.194e-3754.78Homer protein homolog 1 OS=Bos taurus OX=9913 GN=H... [more]
sp|Q9Z214|HOME1_RAT2.497e-3754.78Homer protein homolog 1 OS=Rattus norvegicus OX=10... [more]
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BLAST of WH1 domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
Q5C3H41.328e-5063.41SJCHGC07300 protein (Fragment) OS=Schistosoma japo... [more]
A0A3Q0KDV82.664e-4965.04Putative homer OS=Schistosoma mansoni OX=6183 PE=4... [more]
C1L4V22.835e-4963.41Homer protein OS=Schistosoma japonicum OX=6182 GN=... [more]
A0A3P8EIJ01.172e-4863.64WH1 domain-containing protein OS=Schistosoma matth... [more]
A0A183P3591.374e-4863.64WH1 domain-containing protein OS=Schistosoma matth... [more]
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BLAST of WH1 domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
homer21.541e-4140.81homer scaffold protein 2 [Source:NCBI gene;Acc:111... [more]
homer21.857e-3940.27homer scaffold protein 2 [Source:NCBI gene;Acc:111... [more]
HOMER11.405e-3854.78homer scaffold protein 1 [Source:NCBI gene;Acc:103... [more]
HOMER11.525e-3854.78homer scaffold protein 1 [Source:NCBI gene;Acc:103... [more]
HOMER12.017e-3653.04homer scaffold protein 1 [Source:NCBI gene;Acc:103... [more]
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BLAST of WH1 domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2
Match NameE-valueIdentityDescription
homer3a3.636e-3244.80homer scaffold protein 3a [Source:ZFIN;Acc:ZDB-GEN... [more]
ENSPMAT00000006730.12.227e-927.59pep scaffold:Pmarinus_7.0:GL476423:313891:330988:1... [more]
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BLAST of WH1 domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of WH1 domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO456226.105e-3351.85Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO412081.218e-1128.46Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of WH1 domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
homer25.298e-3849.28homer scaffold protein 2 [Source:NCBI gene;Acc:101... [more]
HOMER18.992e-3854.78homer scaffold protein 1 [Source:NCBI gene;Acc:101... [more]
HOMER12.024e-3754.78homer scaffold protein 1 [Source:NCBI gene;Acc:101... [more]
homer3b1.578e-3650.43homer scaffold protein 3 [Source:NCBI gene;Acc:101... [more]
homer1b2.364e-3652.17homer protein homolog 1-like [Source:NCBI gene;Acc... [more]
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BLAST of WH1 domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 2
Match NameE-valueIdentityDescription
SMESG000035255.10.000e+0100.00SMESG000035255.1[more]
SMESG000063850.12.461e-625.86SMESG000063850.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30019353 ID=SMED30019353|Name=WH1 domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1470bp
CTTTGATGATTATTTTAAAATTTCACAATTTCAATATTCATTAAATATAG
AAATTAATTTAATAGAATTTTAGTAGAGAAATTAAATGGGTGAATTGCCT
ATATTTACTGCGCATGCGCATGTATTCACTATTGATCCTAAGACCAAAAA
GACTTGGATACCTTCTAGTTCAAAGGCTGTTGAGATTAATTATTTTTTCG
ATCCAACTAAAAATTGTTTTCGAATTGTTAGTATTGAAGATACAAGTAAT
GGAAAACAAGTTATTATCAATAGCACATTAACCGAAAAGATGGTTTTCAA
AAAGACTTCCCAGAAATTCGGTCAATGGACAGATTCCAAACAATGCACAA
TATTTGGACTGGGATTCAATTCCGAAGATGATCTCGATGCATTTGTAGAA
AAATTTAAAAGTTGTATAGAAACTATGCGTAACAAATCAGCTCCGAATCA
CAATGACAATGCCAATAATAAGGAGGTCAACAAACGTGAATTGTTAGGCT
TAAACAACAATGTAGTCGGCATATCTAGCAGTGGGCGACAGTGGTCTAAT
CTCACGTCCACTTCCCCGAATCTTAATAATAATCCCAAAGTCCTCTCTCT
AGAAGTTGAATTGGAAAGATTAAATAAAAAAATGGAAGAAATGAAAATCC
AACACCAAGAAGAAATTAAACGATTAAAAGACGAATTAGATCATACAAAT
ACTGGAGCTCTTGCAAATACTGTTGACAATTATAAAACGACAAAAGACAT
GAAATTTCGAGTAGCTGAATTGGAAAATGAAAATAAAGAGTTAAAAAGAA
AATTGAAAGAGTCGAATGAATCAAAGACATTTAGTCAAATATCAAGCCTG
TTGACAGTTCATCAACAAATGGAATCAACCGTAAAACAGCTGTCAAATTA
TCATTATTTGATAGGTCAGAAGTTGTCAGATATAGTTACGTCACAGCCAT
CTGACGTAAAACCACCAATTGCGTACGGATTATAACCTTCTCTTTCTATT
TCTTTCTTATTGCCATTCTTAGAATATGAATATTCCAGTTTAATAAGTCT
ACTTTTTGAAAGACGCATAATTTTTTAATTTTTTTATCCAATACTACTTA
TAACTGTTGAATGGCACATTATTATTGATTTTATTATTCTCGCTACATAC
TTCAATTTTTTATTCTTTTTTTCGTTTCAATTGAATTTTGTTAGGAGAAT
TCGTTTTAATAACCGCTCCATATGATACAGGCTTGTTAGTGAAGGTATTT
CAATAAATACAATAACTTGGTTATGGACATGTCCATATATATATATATAT
ATATATAAGCTGTCATTGTCGTTTGTCGAAAATGAAATAAATTGTAAGAA
ATTTATAAAAAGTGCAAAGTAATTTTAAATTAAAAATGAAATAGTATTCA
CCAATTTGATTAAATAAAGTGTTACCATCATCATGTAAAGAAATATTGTG
AAAACTTGTGATGTAAATAA
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protein sequence of SMED30019353-orf-1

>SMED30019353-orf-1 ID=SMED30019353-orf-1|Name=SMED30019353-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=300bp
MGELPIFTAHAHVFTIDPKTKKTWIPSSSKAVEINYFFDPTKNCFRIVSI
EDTSNGKQVIINSTLTEKMVFKKTSQKFGQWTDSKQCTIFGLGFNSEDDL
DAFVEKFKSCIETMRNKSAPNHNDNANNKEVNKRELLGLNNNVVGISSSG
RQWSNLTSTSPNLNNNPKVLSLEVELERLNKKMEEMKIQHQEEIKRLKDE
LDHTNTGALANTVDNYKTTKDMKFRVAELENENKELKRKLKESNESKTFS
QISSLLTVHQQMESTVKQLSNYHYLIGQKLSDIVTSQPSDVKPPIAYGL*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000070intestinal phagocyte
PLANA:0000101muscle cell
PLANA:0000142posterior region of the whole animal
PLANA:0000208testis
PLANA:0000232copulatory apparatus
Vocabulary: INTERPRO
TermDefinition
IPR000697WH1/EVH1_dom
IPR011993PH-like_dom_sf
Vocabulary: molecular function
TermDefinition
GO:0003779actin binding
GO:0005515protein binding
GO:0019904protein domain specific binding
GO:0030160GKAP/Homer scaffold activity
GO:0035254glutamate receptor binding
GO:0035256G-protein coupled glutamate receptor binding
GO:0042803protein homodimerization activity
GO:0046982protein heterodimerization activity
Vocabulary: cellular component
TermDefinition
GO:0005737cytoplasm
GO:0005829cytosol
GO:0005886plasma membrane
GO:0014069postsynaptic density
GO:0016020membrane
GO:0030054cell junction
GO:0030425dendrite
GO:0032420stereocilium
GO:0032426stereocilium tip
GO:0042995cell projection
GO:0043025neuronal cell body
GO:0045177apical part of cell
GO:0045202synapse
GO:0045211postsynaptic membrane
Vocabulary: biological process
TermDefinition
GO:0007605sensory perception of sound
GO:0008277regulation of G-protein coupled receptor protein signaling pathway
GO:0035584calcium-mediated signaling using intracellular calcium source
GO:0048148behavioral response to cocaine
GO:0048875chemical homeostasis within a tissue
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 219..246
NoneNo IPR availableCOILSCoilCoilcoord: 169..200
NoneNo IPR availablePANTHERPTHR10918HOMERcoord: 1..146
NoneNo IPR availableSUPERFAMILYSSF50729PH domain-likecoord: 1..123
IPR000697WH1/EVH1 domainSMARTSM00461WH1_2coord: 1..111
e-value: 2.0E-21
score: 87.2
IPR000697WH1/EVH1 domainPFAMPF00568WH1coord: 5..109
e-value: 7.8E-27
score: 93.4
IPR000697WH1/EVH1 domainPROSITEPS50229WH1coord: 1..114
score: 19.272
IPR011993PH-like domain superfamilyGENE3DG3DSA:2.30.29.30coord: 1..118
e-value: 6.5E-33
score: 115.0