SH3 and multiple ankyrin repeat domains protein
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30019342 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 8
Homology
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Ensembl Human
Match: SHANK3 (SH3 and multiple ankyrin repeat domains 3 [Source:HGNC Symbol;Acc:HGNC:14294]) HSP 1 Score: 323.553 bits (828), Expect = 2.103e-96 Identity = 173/364 (47.53%), Postives = 233/364 (64.01%), Query Frame = 1
Query: 214 IKVPDLNLKKSVSLILTETVGMLKKSLIGTLSNDLKDAMNYGLFIPPTEGKAGKFLQEERPLNDY--GLHKVHQIVELRYKRRLYRCTNLNINKLKKLHSKTNLKLFMEHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYYKNEDVVCIRGSPKYNDKRR---PS-VATSTFLHRSRS 1287
+ +PDL K + L V K+ ++ L++ L+DA+NYGLF PP+ G+AGKFL EER L +Y L +E RYKRR+Y ++ + KLH+K NLK FM++V KV+++L+KG+DPNF ++GE PL A L +L+KVL GGAHLD+R +G T +H A N A+ LLDLG SP+ D GLTPLYHS + A C E LL D++ +GI DENG QEIHQACRFG HLE+LL Y AD+ +Q + +GNT LHICA NQESCAR+LLFRGA+R V+N +A+Q AI++ N +A +I+ +K+ DVV R +P Y +RR PS +A+ L RS S
Sbjct: 13 VGIPDLQQTKCLRLDPAAPVWAAKQRVLCALNHSLQDALNYGLFQPPSRGRAGKFLDEERLLQEYPPNLDTPLPYLEFRYKRRVYAQNLIDDKQFAKLHTKANLKKFMDYVQLHSTDKVARLLDKGLDPNFHDPDSGECPLSLAAQLDNATDLLKVLKNGGAHLDFRTRDGLTAVHCATRQRNAAALTTLLDLGASPDYKDSRGLTPLYHSALGGGDALCCELLLHDHAQLGITDENGWQEIHQACRFGHVQHLEHLLFYGADMGAQNA-SGNTALHICALYNQESCARVLLFRGANRDVRNYNSQTAFQVAIIAGNFELAEVIKTHKDSDVVPFRETPSYAKRRRLAGPSGLASPRPLQRSAS 375 HSP 2 Score: 90.1225 bits (222), Expect = 1.123e-17 Identity = 50/97 (51.55%), Postives = 67/97 (69.07%), Query Frame = 1
Query: 1777 RVVVLQK-NSQGFGFVIRGLKASSTIN-FRPTLKNPALQYFEEVEVNSVAARAGLKKGDFILEINNLSVVSASHEDTVRLIKASGDILAMKVVTVNK 2061
+V VLQK + +GFGFV+RG KA + I F PT PALQY E V+V VA RAGL+ GDF++E+N ++VV H+ V LI+ G+ L MKVV+V +
Sbjct: 556 KVAVLQKRDHEGFGFVLRGAKAETPIEEFTPTPAFPALQYLESVDVEGVAWRAGLRTGDFLIEVNGVNVVKVGHKQVVALIRQGGNRLVMKVVSVTR 652
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Ensembl Human
Match: SHANK3 (SH3 and multiple ankyrin repeat domains 3 [Source:HGNC Symbol;Acc:HGNC:14294]) HSP 1 Score: 324.709 bits (831), Expect = 2.289e-91 Identity = 173/364 (47.53%), Postives = 233/364 (64.01%), Query Frame = 1
Query: 214 IKVPDLNLKKSVSLILTETVGMLKKSLIGTLSNDLKDAMNYGLFIPPTEGKAGKFLQEERPLNDY--GLHKVHQIVELRYKRRLYRCTNLNINKLKKLHSKTNLKLFMEHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYYKNEDVVCIRGSPKYNDKRR---PS-VATSTFLHRSRS 1287
+ +PDL K + L V K+ ++ L++ L+DA+NYGLF PP+ G+AGKFL EER L +Y L +E RYKRR+Y ++ + KLH+K NLK FM++V KV+++L+KG+DPNF ++GE PL A L +L+KVL GGAHLD+R +G T +H A N A+ LLDLG SP+ D GLTPLYHS + A C E LL D++ +GI DENG QEIHQACRFG HLE+LL Y AD+ +Q + +GNT LHICA NQESCAR+LLFRGA+R V+N +A+Q AI++ N +A +I+ +K+ DVV R +P Y +RR PS +A+ L RS S
Sbjct: 13 VGIPDLQQTKCLRLDPAAPVWAAKQRVLCALNHSLQDALNYGLFQPPSRGRAGKFLDEERLLQEYPPNLDTPLPYLEFRYKRRVYAQNLIDDKQFAKLHTKANLKKFMDYVQLHSTDKVARLLDKGLDPNFHDPDSGECPLSLAAQLDNATDLLKVLKNGGAHLDFRTRDGLTAVHCATRQRNAAALTTLLDLGASPDYKDSRGLTPLYHSALGGGDALCCELLLHDHAQLGITDENGWQEIHQACRFGHVQHLEHLLFYGADMGAQNA-SGNTALHICALYNQESCARVLLFRGANRDVRNYNSQTAFQVAIIAGNFELAEVIKTHKDSDVVPFRETPSYAKRRRLAGPSGLASPRPLQRSAS 375 HSP 2 Score: 90.8929 bits (224), Expect = 1.311e-17 Identity = 50/97 (51.55%), Postives = 67/97 (69.07%), Query Frame = 1
Query: 1777 RVVVLQK-NSQGFGFVIRGLKASSTIN-FRPTLKNPALQYFEEVEVNSVAARAGLKKGDFILEINNLSVVSASHEDTVRLIKASGDILAMKVVTVNK 2061
+V VLQK + +GFGFV+RG KA + I F PT PALQY E V+V VA RAGL+ GDF++E+N ++VV H+ V LI+ G+ L MKVV+V +
Sbjct: 563 KVAVLQKRDHEGFGFVLRGAKAETPIEEFTPTPAFPALQYLESVDVEGVAWRAGLRTGDFLIEVNGVNVVKVGHKQVVALIRQGGNRLVMKVVSVTR 659
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Ensembl Human
Match: SHANK2 (SH3 and multiple ankyrin repeat domains 2 [Source:HGNC Symbol;Acc:HGNC:14295]) HSP 1 Score: 314.694 bits (805), Expect = 4.820e-88 Identity = 166/359 (46.24%), Postives = 230/359 (64.07%), Query Frame = 1
Query: 226 DLNLKKSVSLILTETVGMLKKSLIGTLSNDLKDAMNYGLFIPPTEGKAGKFLQEERPLNDYGLHKVHQI--VELRYKRRLYRCTNLNINKLKKLHSKTNLKLFMEHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYYKNEDVVCIRGSPKY-NDKRRP--SVATSTFLHRSRS 1287
DL K + TV + K+ ++ TL+ LKD +NYGLF P + G+ GKFL EER L +Y + +E RYK+R+Y+ +L+ +L KLH+KTNLK M+H+ + + K++KML++G+DPNF ETGETPL A L VE+IK L GGAHLD+R +G T LH AA N A+K LL+LG SP+ D GLTPLYH+ I C E LL +++ + +DENG EIHQACR+G HLE+LL Y AD+++Q + +GNT LHICA NQ+SCAR+LLFRG ++ +KN + +Q AI++ N +A I+ +K D+V R +P Y N +RRP ++A L RS S
Sbjct: 65 DLQQTKCIRFNPDATVWVAKQRILCTLTQSLKDVLNYGLFQPASNGRDGKFLDEERLLREYPQPVGEGVPSLEFRYKKRVYKQASLDEKQLAKLHTKTNLKKCMDHIQHRLVEKITKMLDRGLDPNFHDPETGETPLTLAAQLDDSVEVIKALKNGGAHLDFRAKDGMTALHKAARARNQVALKTLLELGASPDYKDSYGLTPLYHTAIVGGDPYCCELLLHEHATVCCKDENGWHEIHQACRYGHVQHLEHLLFYGADMSAQNA-SGNTALHICALYNQDSCARVLLFRGGNKELKNYNSQTPFQVAIIAGNFELAEYIKNHKETDIVPFREAPAYSNRRRRPPNTLAAPRVLLRSNS 422 HSP 2 Score: 95.9005 bits (237), Expect = 3.661e-19 Identity = 48/98 (48.98%), Postives = 67/98 (68.37%), Query Frame = 1
Query: 1777 RVVVLQK-NSQGFGFVIRGLKASSTIN-FRPTLKNPALQYFEEVEVNSVAARAGLKKGDFILEINNLSVVSASHEDTVRLIKASGDILAMKVVTVNKD 2064
+ VVLQK +++GFGFV+RG KA + I F PT PALQY E V+ VA +AGL+ GDF++E+NN +VV H V +I+ G+ L +KVVTV ++
Sbjct: 625 KTVVLQKKDNEGFGFVLRGAKADTPIEEFTPTPAFPALQYLESVDEGGVAWQAGLRTGDFLIEVNNENVVKVGHRQVVNMIRQGGNHLVLKVVTVTRN 722
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Ensembl Human
Match: SHANK1 (SH3 and multiple ankyrin repeat domains 1 [Source:HGNC Symbol;Acc:HGNC:15474]) HSP 1 Score: 311.997 bits (798), Expect = 4.828e-87 Identity = 160/360 (44.44%), Postives = 228/360 (63.33%), Query Frame = 1
Query: 172 SVATNNNNQCFKFEIKVPDLNLKKSVSLILTETVGMLKKSLIGTLSNDLKDAMNYGLFIPPTEGKAGKFLQEERPLNDY--GLHKVHQIVELRYKRRLYRCTNLNINKLKKLHSKTNLKLFMEHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYYKNEDVVCIRGSPKYNDKRR 1245
SV + + F I +PDL+ K + T+ K+ ++ LS L+D +NYGLF P T G+ FL+EER L +Y K +E RYK R+Y+ TNL+ +L KLH+KT LK F+E+V KV+++L+KG+DPN+ ++GETPL A VE+I+ L GGAH+D+R +G T LH AA + A+ LLDLG SPN D+ GLTPL+H+ + C E LLF+ + +GI DENG QEIHQAC+ G + HLE+LL Y A+ +Q + +GNT LHICA N+E+CAR+LL+RGAD+ VKN G + +Q A+++ N + LI+ ++ +DVV + SPKY +RR
Sbjct: 63 SVPDDAHFSMMVFRIGIPDLHQTKCLRFNPDATIWTAKQQVLCALSESLQDVLNYGLFQPATSGRDANFLEEERLLREYPQSFEKGVPYLEFRYKTRVYKQTNLDEKQLAKLHTKTGLKKFLEYVQLGTSDKVARLLDKGLDPNYHDSDSGETPLTLAAQTEGSVEVIRTLCLGGAHIDFRARDGMTALHKAACARHCLALTALLDLGGSPNYKDRRGLTPLFHTAMVGGDPRCCELLLFNRAQLGIADENGWQEIHQACQRGHSQHLEHLLFYGAEPGAQNA-SGNTALHICALYNKETCARILLYRGADKDVKNNNGQTPFQVAVIAGNFELGELIRNHREQDVVPFQESPKYAARRR 421 HSP 2 Score: 94.7449 bits (234), Expect = 7.882e-19 Identity = 49/103 (47.57%), Postives = 67/103 (65.05%), Query Frame = 1
Query: 1777 RVVVLQK-NSQGFGFVIRGLKASSTIN-FRPTLKNPALQYFEEVEVNSVAARAGLKKGDFILEINNLSVVSASHEDTVRLIKASGDILAMKVVTVNKDK-LDE 2076
+ V+LQK +S+GFGFV+RG KA + I F PT PALQY E V+ VA RAGL+ GDF++E+N +VV H V +I+ G+ L +KVV V + +DE
Sbjct: 653 KTVLLQKKDSEGFGFVLRGAKAQTPIEEFTPTPAFPALQYLESVDEGGVAWRAGLRMGDFLIEVNGQNVVKVGHRQVVNMIRQGGNTLMVKVVMVTRHPDMDE 755
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Ensembl Human
Match: SHANK1 (SH3 and multiple ankyrin repeat domains 1 [Source:HGNC Symbol;Acc:HGNC:15474]) HSP 1 Score: 311.997 bits (798), Expect = 5.040e-87 Identity = 160/360 (44.44%), Postives = 228/360 (63.33%), Query Frame = 1
Query: 172 SVATNNNNQCFKFEIKVPDLNLKKSVSLILTETVGMLKKSLIGTLSNDLKDAMNYGLFIPPTEGKAGKFLQEERPLNDY--GLHKVHQIVELRYKRRLYRCTNLNINKLKKLHSKTNLKLFMEHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYYKNEDVVCIRGSPKYNDKRR 1245
SV + + F I +PDL+ K + T+ K+ ++ LS L+D +NYGLF P T G+ FL+EER L +Y K +E RYK R+Y+ TNL+ +L KLH+KT LK F+E+V KV+++L+KG+DPN+ ++GETPL A VE+I+ L GGAH+D+R +G T LH AA + A+ LLDLG SPN D+ GLTPL+H+ + C E LLF+ + +GI DENG QEIHQAC+ G + HLE+LL Y A+ +Q + +GNT LHICA N+E+CAR+LL+RGAD+ VKN G + +Q A+++ N + LI+ ++ +DVV + SPKY +RR
Sbjct: 63 SVPDDAHFSMMVFRIGIPDLHQTKCLRFNPDATIWTAKQQVLCALSESLQDVLNYGLFQPATSGRDANFLEEERLLREYPQSFEKGVPYLEFRYKTRVYKQTNLDEKQLAKLHTKTGLKKFLEYVQLGTSDKVARLLDKGLDPNYHDSDSGETPLTLAAQTEGSVEVIRTLCLGGAHIDFRARDGMTALHKAACARHCLALTALLDLGGSPNYKDRRGLTPLFHTAMVGGDPRCCELLLFNRAQLGIADENGWQEIHQACQRGHSQHLEHLLFYGAEPGAQNA-SGNTALHICALYNKETCARILLYRGADKDVKNNNGQTPFQVAVIAGNFELGELIRNHREQDVVPFQESPKYAARRR 421 HSP 2 Score: 94.7449 bits (234), Expect = 8.168e-19 Identity = 49/103 (47.57%), Postives = 67/103 (65.05%), Query Frame = 1
Query: 1777 RVVVLQK-NSQGFGFVIRGLKASSTIN-FRPTLKNPALQYFEEVEVNSVAARAGLKKGDFILEINNLSVVSASHEDTVRLIKASGDILAMKVVTVNKDK-LDE 2076
+ V+LQK +S+GFGFV+RG KA + I F PT PALQY E V+ VA RAGL+ GDF++E+N +VV H V +I+ G+ L +KVV V + +DE
Sbjct: 662 KTVLLQKKDSEGFGFVLRGAKAQTPIEEFTPTPAFPALQYLESVDEGGVAWRAGLRMGDFLIEVNGQNVVKVGHRQVVNMIRQGGNTLMVKVVMVTRHPDMDE 764
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Ensembl Celegans
Match: shn-1 (pep chromosome:WBcel235:II:11384748:11390862:-1 gene:WBGene00006444.1 transcript:C33B4.3b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:shn-1) HSP 1 Score: 285.034 bits (728), Expect = 1.852e-80 Identity = 152/378 (40.21%), Postives = 232/378 (61.38%), Query Frame = 1
Query: 184 NNNNQCFKFEIKVPDLNLKKSVSLILTETVGMLKKSLIGTLSNDLKDAMNYGLFIPPTEGKAGKFLQEERPLNDYGLHKVHQIVELRYKRRLYRCTNLNINKLKKLHSKTNLKLFMEHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSII-SDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYYKNEDVVCIRGSPKYNDKRRPSVATSTFLHRSRSASRIMDISQ 1314
N +I VP+LN++K +++ + + +K+ L+ TL L A NYGLF+PP +G+AGKFL E+R + DY +EL+YK+R+Y+ NL+ +LK +H+K LK FM++V + KV KM ++G+D NF + GETPL A + +I L+ GGAH+D+R+S G T +H AA L + E VK L++LG SPN D GLTPLY++++ +D E LL + + IG+ D +G EIHQAC+ G T H+E+LL + I+++ + NGN+PLH+CA N+ CAR+LLFRGAD N+ G +A + + N +A ++Q + + V RG+P+Y+ +RR S+ + R RS S+ SQ
Sbjct: 2 NQEEDTVNLQIFVPELNVRKFLAVTQNDFIWDVKRKLLATLPQALPQAFNYGLFLPPCDGRAGKFLLEDRTIRDYPFTDCVPYLELKYKKRVYKMLNLDEKQLKAMHTKGQLKKFMDYVQQKNNEKVEKMCSQGLDANFHDAQ-GETPLTLAAGIPNNRAVIVSLIGGGAHVDFRNSEGQTAMHKAAFLSSFENVKTLIELGASPNYRDPIGLTPLYYNMLTADSNDQVAEILLREAADIGVTDMHGNHEIHQACKNGLTKHVEHLLYFGGQIDAE-NVNGNSPLHVCAVNNRPECARVLLFRGADHLAVNKQGQTALHVSHIVGNPGVADVVQAHNPKSSVPYRGTPQYSTRRR----LSSTITRRRSMSQSSICSQ 373 HSP 2 Score: 97.4413 bits (241), Expect = 2.977e-20 Identity = 41/97 (42.27%), Postives = 70/97 (72.16%), Query Frame = 1
Query: 1771 LPRVVVLQKNSQGFGFVIRGLK-ASSTINFRPTLKNPALQYFEEVEVNSVAARAGLKKGDFILEINNLSVVSASHEDTVRLIKASGDILAMKVVTVN 2058
+ R++V+ + +GFGF++RG K + +NF PT + PALQ+FE V+++ +A RAGL+ GD++LEI+ + V SH++ V I+ +GD + +KV+TV+
Sbjct: 433 IARILVIPRGVKGFGFILRGAKHVAMPLNFEPTAQVPALQFFEGVDMSGMAVRAGLRPGDYLLEIDGIDVRRCSHDEVVEFIQQAGDTITLKVITVD 529
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Ensembl Celegans
Match: shn-1 (pep chromosome:WBcel235:II:11384594:11390862:-1 gene:WBGene00006444.1 transcript:C33B4.3a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:shn-1) HSP 1 Score: 285.034 bits (728), Expect = 7.491e-80 Identity = 152/378 (40.21%), Postives = 232/378 (61.38%), Query Frame = 1
Query: 184 NNNNQCFKFEIKVPDLNLKKSVSLILTETVGMLKKSLIGTLSNDLKDAMNYGLFIPPTEGKAGKFLQEERPLNDYGLHKVHQIVELRYKRRLYRCTNLNINKLKKLHSKTNLKLFMEHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSII-SDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYYKNEDVVCIRGSPKYNDKRRPSVATSTFLHRSRSASRIMDISQ 1314
N +I VP+LN++K +++ + + +K+ L+ TL L A NYGLF+PP +G+AGKFL E+R + DY +EL+YK+R+Y+ NL+ +LK +H+K LK FM++V + KV KM ++G+D NF + GETPL A + +I L+ GGAH+D+R+S G T +H AA L + E VK L++LG SPN D GLTPLY++++ +D E LL + + IG+ D +G EIHQAC+ G T H+E+LL + I+++ + NGN+PLH+CA N+ CAR+LLFRGAD N+ G +A + + N +A ++Q + + V RG+P+Y+ +RR S+ + R RS S+ SQ
Sbjct: 2 NQEEDTVNLQIFVPELNVRKFLAVTQNDFIWDVKRKLLATLPQALPQAFNYGLFLPPCDGRAGKFLLEDRTIRDYPFTDCVPYLELKYKKRVYKMLNLDEKQLKAMHTKGQLKKFMDYVQQKNNEKVEKMCSQGLDANFHDAQ-GETPLTLAAGIPNNRAVIVSLIGGGAHVDFRNSEGQTAMHKAAFLSSFENVKTLIELGASPNYRDPIGLTPLYYNMLTADSNDQVAEILLREAADIGVTDMHGNHEIHQACKNGLTKHVEHLLYFGGQIDAE-NVNGNSPLHVCAVNNRPECARVLLFRGADHLAVNKQGQTALHVSHIVGNPGVADVVQAHNPKSSVPYRGTPQYSTRRR----LSSTITRRRSMSQSSICSQ 373 HSP 2 Score: 97.8265 bits (242), Expect = 2.919e-20 Identity = 41/97 (42.27%), Postives = 70/97 (72.16%), Query Frame = 1
Query: 1771 LPRVVVLQKNSQGFGFVIRGLK-ASSTINFRPTLKNPALQYFEEVEVNSVAARAGLKKGDFILEINNLSVVSASHEDTVRLIKASGDILAMKVVTVN 2058
+ R++V+ + +GFGF++RG K + +NF PT + PALQ+FE V+++ +A RAGL+ GD++LEI+ + V SH++ V I+ +GD + +KV+TV+
Sbjct: 433 IARILVIPRGVKGFGFILRGAKHVAMPLNFEPTAQVPALQFFEGVDMSGMAVRAGLRPGDYLLEIDGIDVRRCSHDEVVEFIQQAGDTITLKVITVD 529
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Ensembl Celegans
Match: shn-1 (pep chromosome:WBcel235:II:11384594:11390862:-1 gene:WBGene00006444.1 transcript:C33B4.3c.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:shn-1) HSP 1 Score: 285.034 bits (728), Expect = 8.978e-80 Identity = 152/378 (40.21%), Postives = 232/378 (61.38%), Query Frame = 1
Query: 184 NNNNQCFKFEIKVPDLNLKKSVSLILTETVGMLKKSLIGTLSNDLKDAMNYGLFIPPTEGKAGKFLQEERPLNDYGLHKVHQIVELRYKRRLYRCTNLNINKLKKLHSKTNLKLFMEHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSII-SDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYYKNEDVVCIRGSPKYNDKRRPSVATSTFLHRSRSASRIMDISQ 1314
N +I VP+LN++K +++ + + +K+ L+ TL L A NYGLF+PP +G+AGKFL E+R + DY +EL+YK+R+Y+ NL+ +LK +H+K LK FM++V + KV KM ++G+D NF + GETPL A + +I L+ GGAH+D+R+S G T +H AA L + E VK L++LG SPN D GLTPLY++++ +D E LL + + IG+ D +G EIHQAC+ G T H+E+LL + I+++ + NGN+PLH+CA N+ CAR+LLFRGAD N+ G +A + + N +A ++Q + + V RG+P+Y+ +RR S+ + R RS S+ SQ
Sbjct: 2 NQEEDTVNLQIFVPELNVRKFLAVTQNDFIWDVKRKLLATLPQALPQAFNYGLFLPPCDGRAGKFLLEDRTIRDYPFTDCVPYLELKYKKRVYKMLNLDEKQLKAMHTKGQLKKFMDYVQQKNNEKVEKMCSQGLDANFHDAQ-GETPLTLAAGIPNNRAVIVSLIGGGAHVDFRNSEGQTAMHKAAFLSSFENVKTLIELGASPNYRDPIGLTPLYYNMLTADSNDQVAEILLREAADIGVTDMHGNHEIHQACKNGLTKHVEHLLYFGGQIDAE-NVNGNSPLHVCAVNNRPECARVLLFRGADHLAVNKQGQTALHVSHIVGNPGVADVVQAHNPKSSVPYRGTPQYSTRRR----LSSTITRRRSMSQSSICSQ 373 HSP 2 Score: 97.4413 bits (241), Expect = 3.202e-20 Identity = 41/97 (42.27%), Postives = 70/97 (72.16%), Query Frame = 1
Query: 1771 LPRVVVLQKNSQGFGFVIRGLK-ASSTINFRPTLKNPALQYFEEVEVNSVAARAGLKKGDFILEINNLSVVSASHEDTVRLIKASGDILAMKVVTVN 2058
+ R++V+ + +GFGF++RG K + +NF PT + PALQ+FE V+++ +A RAGL+ GD++LEI+ + V SH++ V I+ +GD + +KV+TV+
Sbjct: 433 IARILVIPRGVKGFGFILRGAKHVAMPLNFEPTAQVPALQFFEGVDMSGMAVRAGLRPGDYLLEIDGIDVRRCSHDEVVEFIQQAGDTITLKVITVD 529
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Ensembl Celegans
Match: unc-44 (AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86]) HSP 1 Score: 79.337 bits (194), Expect = 1.403e-14 Identity = 60/214 (28.04%), Postives = 103/214 (48.13%), Query Frame = 1
Query: 553 IGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSI-IGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYYK 1191
I V +L +G +P+ + GETPL A Q ++++VL+ GA +D + TPLH A+ LGN + V +LL G + N ++ +PL+ I + +L D++ + + G +H A ++G + LL+ ++ + KN TPLH+ A+ N + A LLL GA + G++ A + IA + +K
Sbjct: 438 INIVIYLLQQGANPDVETVR-GETPLHLAARANQ-TDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLH--IAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVDIE-GKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFK 646 HSP 2 Score: 75.485 bits (184), Expect = 2.047e-13 Identity = 64/236 (27.12%), Postives = 115/236 (48.73%), Query Frame = 1
Query: 472 NLNINKLKKLHSKTNLKLFMEHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLI 1179
++ ++ L LH H G+ + K+ +L++ DPN + G TPL AC + ++++++L++ A ++ +G TPLH AA +G + V LL G +P+ G TPL+ + ++ L+ + + + + +H A R G T + LLQ A+ N+ T+++ +PLHI A QE A +LL AD+T+ + G + A N + L+
Sbjct: 354 DVTVDYLTPLH-------VAAHCGHVRVAKL--LLDRSADPNSRAL-NGFTPLHIACKKNR-IKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARAN-QTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNA-TTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLL 576 HSP 3 Score: 71.633 bits (174), Expect = 3.656e-12 Identity = 51/164 (31.10%), Postives = 77/164 (46.95%), Query Frame = 1
Query: 673 VLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKN 1164
+L+E GA NG+TPLH AA +E LL PN + G TPL+ S + + L+ + S +G + NGL +H + + L A+INS+T+ G TPLH+ + Q + + L+ GAD K RA ++ QA + N
Sbjct: 608 LLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLS-AQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNA-GYTPLHVACHFGQLNMVKFLVENGADVGEKTRASYTPLHQAAQQGHNN 769 HSP 4 Score: 68.5514 bits (166), Expect = 2.826e-11 Identity = 67/247 (27.13%), Postives = 112/247 (45.34%), Query Frame = 1
Query: 535 HVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTP----------------LYHSIISDP-----------AAAC----TERLLFDYSI-IGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLI 1179
H G+ ++G++ +L KG + N+Q + +PL A + + +L+ GA +D R + TPLH AA G+ + V +L+ G + + GL P LYH D AA C +LL D S NG +H AC+ R +E LL+YRA I + T+++G TPLH+ A++ + LL +GA+ V+ G + A ++ ++ ++
Sbjct: 236 HYGHENVGQL--LLEKGANVNYQARHN-ISPLHVATKWGR-TNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEA-TTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVL 477 HSP 5 Score: 63.5438 bits (153), Expect = 1.008e-9 Identity = 65/219 (29.68%), Postives = 105/219 (47.95%), Query Frame = 1
Query: 538 VGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEG---LTPLYHSII--SDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLI 1179
+GN DI V +L G + N ++ +PL A Q E+ +L++ A G TPLH A+ GNLE V++LL+ G +D EG +TPL+ + +D A LL + + +NG +H A + + LLQ++AD N++ S+ G TPLH+ A + + LL+ G+D K G +A D+ +A ++
Sbjct: 501 LGNTDI--VILLLQAGANSNATTRDN-YSPLHIAAKEGQE-EVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERG---TPVDIEGKNQVTPLHVAAHYNNDKVAML---LLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAK-SRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQEDHVPVAQIL 708 HSP 6 Score: 62.7734 bits (151), Expect = 1.551e-9 Identity = 56/177 (31.64%), Postives = 85/177 (48.02%), Query Frame = 1
Query: 664 LIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENG---LQEIHQACRFGRTHHLEYLLQ--YRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLI 1179
++ +LVE GA+++ + NG TPL+ AA + E VK LL G + ++G TPL A A + +++ D G L +H A + T LLQ + D+ TSK+G TPLHI A+ E+ +LLL +GA+ + R S A N+A L+
Sbjct: 114 IVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPL--------AVALQQGHDRVVAVLLENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDV---TSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLL 279 HSP 7 Score: 57.7658 bits (138), Expect = 6.271e-8 Identity = 46/174 (26.44%), Postives = 80/174 (45.98%), Query Frame = 1
Query: 670 KVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYYK 1191
++L+E GA+++Y+ + +PLH A G +LL G ++ ++ LTPL H + L+ + I + +NGL +H A + LL +RA ++ T + TPLH+ A+ A+LLL R AD + G + A + + L+ Y+
Sbjct: 244 QLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPL-HCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTV-DYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYR 415 HSP 8 Score: 51.2174 bits (121), Expect = 5.794e-6 Identity = 38/100 (38.00%), Postives = 51/100 (51.00%), Query Frame = 1
Query: 532 EHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPL 831
+HV A I + N G + N + G TPL AC Q + ++K LVE GA + + +TPLH AA G+ V+ LL+ G SPN G TPL
Sbjct: 700 DHVPVAQI-----LYNNGAEINSKTN-AGYTPLHVACHFGQ-LNMVKFLVENGADVGEKTRASYTPLHQAAQQGHNNCVRYLLENGASPNEQTATGQTPL 792
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Ensembl Celegans
Match: unc-44 (AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86]) HSP 1 Score: 79.337 bits (194), Expect = 1.403e-14 Identity = 60/214 (28.04%), Postives = 103/214 (48.13%), Query Frame = 1
Query: 553 IGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSI-IGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYYK 1191
I V +L +G +P+ + GETPL A Q ++++VL+ GA +D + TPLH A+ LGN + V +LL G + N ++ +PL+ I + +L D++ + + G +H A ++G + LL+ ++ + KN TPLH+ A+ N + A LLL GA + G++ A + IA + +K
Sbjct: 438 INIVIYLLQQGANPDVETVR-GETPLHLAARANQ-TDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLH--IAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVDIE-GKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFK 646 HSP 2 Score: 75.485 bits (184), Expect = 2.047e-13 Identity = 64/236 (27.12%), Postives = 115/236 (48.73%), Query Frame = 1
Query: 472 NLNINKLKKLHSKTNLKLFMEHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLI 1179
++ ++ L LH H G+ + K+ +L++ DPN + G TPL AC + ++++++L++ A ++ +G TPLH AA +G + V LL G +P+ G TPL+ + ++ L+ + + + + +H A R G T + LLQ A+ N+ T+++ +PLHI A QE A +LL AD+T+ + G + A N + L+
Sbjct: 354 DVTVDYLTPLH-------VAAHCGHVRVAKL--LLDRSADPNSRAL-NGFTPLHIACKKNR-IKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARAN-QTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNA-TTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLL 576 HSP 3 Score: 71.633 bits (174), Expect = 3.656e-12 Identity = 51/164 (31.10%), Postives = 77/164 (46.95%), Query Frame = 1
Query: 673 VLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKN 1164
+L+E GA NG+TPLH AA +E LL PN + G TPL+ S + + L+ + S +G + NGL +H + + L A+INS+T+ G TPLH+ + Q + + L+ GAD K RA ++ QA + N
Sbjct: 608 LLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLS-AQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNA-GYTPLHVACHFGQLNMVKFLVENGADVGEKTRASYTPLHQAAQQGHNN 769 HSP 4 Score: 68.5514 bits (166), Expect = 2.826e-11 Identity = 67/247 (27.13%), Postives = 112/247 (45.34%), Query Frame = 1
Query: 535 HVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTP----------------LYHSIISDP-----------AAAC----TERLLFDYSI-IGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLI 1179
H G+ ++G++ +L KG + N+Q + +PL A + + +L+ GA +D R + TPLH AA G+ + V +L+ G + + GL P LYH D AA C +LL D S NG +H AC+ R +E LL+YRA I + T+++G TPLH+ A++ + LL +GA+ V+ G + A ++ ++ ++
Sbjct: 236 HYGHENVGQL--LLEKGANVNYQARHN-ISPLHVATKWGR-TNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEA-TTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVL 477 HSP 5 Score: 63.5438 bits (153), Expect = 1.008e-9 Identity = 65/219 (29.68%), Postives = 105/219 (47.95%), Query Frame = 1
Query: 538 VGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEG---LTPLYHSII--SDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLI 1179
+GN DI V +L G + N ++ +PL A Q E+ +L++ A G TPLH A+ GNLE V++LL+ G +D EG +TPL+ + +D A LL + + +NG +H A + + LLQ++AD N++ S+ G TPLH+ A + + LL+ G+D K G +A D+ +A ++
Sbjct: 501 LGNTDI--VILLLQAGANSNATTRDN-YSPLHIAAKEGQE-EVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERG---TPVDIEGKNQVTPLHVAAHYNNDKVAML---LLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAK-SRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQEDHVPVAQIL 708 HSP 6 Score: 62.7734 bits (151), Expect = 1.551e-9 Identity = 56/177 (31.64%), Postives = 85/177 (48.02%), Query Frame = 1
Query: 664 LIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENG---LQEIHQACRFGRTHHLEYLLQ--YRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLI 1179
++ +LVE GA+++ + NG TPL+ AA + E VK LL G + ++G TPL A A + +++ D G L +H A + T LLQ + D+ TSK+G TPLHI A+ E+ +LLL +GA+ + R S A N+A L+
Sbjct: 114 IVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPL--------AVALQQGHDRVVAVLLENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDV---TSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLL 279 HSP 7 Score: 57.7658 bits (138), Expect = 6.271e-8 Identity = 46/174 (26.44%), Postives = 80/174 (45.98%), Query Frame = 1
Query: 670 KVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYYK 1191
++L+E GA+++Y+ + +PLH A G +LL G ++ ++ LTPL H + L+ + I + +NGL +H A + LL +RA ++ T + TPLH+ A+ A+LLL R AD + G + A + + L+ Y+
Sbjct: 244 QLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPL-HCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTV-DYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYR 415 HSP 8 Score: 51.2174 bits (121), Expect = 5.794e-6 Identity = 38/100 (38.00%), Postives = 51/100 (51.00%), Query Frame = 1
Query: 532 EHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPL 831
+HV A I + N G + N + G TPL AC Q + ++K LVE GA + + +TPLH AA G+ V+ LL+ G SPN G TPL
Sbjct: 700 DHVPVAQI-----LYNNGAEINSKTN-AGYTPLHVACHFGQ-LNMVKFLVENGADVGEKTRASYTPLHQAAQQGHNNCVRYLLENGASPNEQTATGQTPL 792
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Ensembl Fly
Match: Prosap (gene:FBgn0040752 transcript:FBtr0087601) HSP 1 Score: 333.569 bits (854), Expect = 1.486e-94 Identity = 163/348 (46.84%), Postives = 226/348 (64.94%), Query Frame = 1
Query: 214 IKVPDLNLKKSVSLILTETVGMLKKSLIGTLSNDLKDAMNYGLFIPPTEGKAGKFLQEERPLNDYGLHKVHQIVELRYKRRLYRCTNLNINKLKKLHSKTNLKLFMEHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYYKNEDVVCIRGSPKYNDKRRPSVA 1257
I VP+LN+ K + V +K+ ++ +L +LK++ NYGLF PP GKAGKFL EER L DY + +EL+YKRR+Y+ L+ +LK LH++ NL+ F+E + + K++KM KG+DPNF E+G+TPL A +P +L+ LV GGA LDYR +G T LH A +LEAV LL+LG SPN D G+TPLY SI A TE LL D++ +GI+D G E+HQACR G HLE+LL Y AD++ + + +GN+PLH+CA NQE+CAR+LLFRGA R +N A + YQ A+++ N +A +I+ YK+ED+V RG P+YN KRR +
Sbjct: 24 IHVPELNVYKCLQFPSERLVWDVKQQVLASLPKELKESFNYGLFAPPANGKAGKFLDEERRLGDYPFNGPVGYLELKYKRRVYKMLTLDERQLKALHTRANLRRFLECINGGHVEKIAKMCAKGLDPNFHCSESGDTPLTVATGAKKPNKLLIALVNGGALLDYRTKDGSTALHRAVEHDSLEAVSTLLELGASPNYRDGRGITPLYISITRKCEAKITESLLHDHATLGIQDSQGWNEVHQACRHGLVQHLEHLLFYGADMDGRNA-SGNSPLHVCAVNNQEACARMLLFRGAQRGAQNFANQTPYQVAVIAGNLELAEIIENYKSEDIVPFRGPPRYNPKRRSGIG 370 HSP 2 Score: 95.9005 bits (237), Expect = 1.790e-19 Identity = 45/94 (47.87%), Postives = 65/94 (69.15%), Query Frame = 1
Query: 1774 PRVVVLQKNSQGFGFVIRGLKASSTI-NFRPTLKNPALQYFEEVEVNSVAARAGLKKGDFILEINNLSVVSASHEDTVRLIKASGDILAMKVVT 2052
PR VVL + +GFGF++RG KASS + RP+ + PALQY ++V+ VA AGL+ GDF+L IN V SASHE V +I+++G ++ + VV+
Sbjct: 706 PRSVVLHRAKRGFGFILRGAKASSQLMQLRPSERFPALQYLDDVDPGGVADMAGLRPGDFLLTINGEDVTSASHEQVVEMIRSAGALVNLTVVS 799
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Ensembl Fly
Match: Prosap (gene:FBgn0040752 transcript:FBtr0339763) HSP 1 Score: 313.153 bits (801), Expect = 7.510e-88 Identity = 154/330 (46.67%), Postives = 215/330 (65.15%), Query Frame = 1
Query: 214 IKVPDLNLKKSVSLILTETVGMLKKSLIGTLSNDLKDAMNYGLFIPPTEGKAGKFLQEERPLNDYGLHKVHQIVELRYKRRLYRCTNLNINKLKKLHSKTNLKLFMEHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYYKNEDV 1203
I VP+LN+ K + V +K+ ++ +L +LK++ NYGLF PP GKAGKFL EER L DY + +EL+YKRR+Y+ L+ +LK LH++ NL+ F+E + + K++KM KG+DPNF E+G+TPL A +P +L+ LV GGA LDYR +G T LH A +LEAV LL+LG SPN D G+TPLY SI A TE LL D++ +GI+D G E+HQACR G HLE+LL Y AD++ + + +GN+PLH+CA NQE+CAR+LLFRGA R +N A + YQ A+++ N +A +I+ YK+ED+
Sbjct: 24 IHVPELNVYKCLQFPSERLVWDVKQQVLASLPKELKESFNYGLFAPPANGKAGKFLDEERRLGDYPFNGPVGYLELKYKRRVYKMLTLDERQLKALHTRANLRRFLECINGGHVEKIAKMCAKGLDPNFHCSESGDTPLTVATGAKKPNKLLIALVNGGALLDYRTKDGSTALHRAVEHDSLEAVSTLLELGASPNYRDGRGITPLYISITRKCEAKITESLLHDHATLGIQDSQGWNEVHQACRHGLVQHLEHLLFYGADMDGRNA-SGNSPLHVCAVNNQEACARMLLFRGAQRGAQNFANQTPYQVAVIAGNLELAEIIENYKSEDI 352 HSP 2 Score: 95.9005 bits (237), Expect = 1.689e-19 Identity = 45/94 (47.87%), Postives = 65/94 (69.15%), Query Frame = 1
Query: 1774 PRVVVLQKNSQGFGFVIRGLKASSTI-NFRPTLKNPALQYFEEVEVNSVAARAGLKKGDFILEINNLSVVSASHEDTVRLIKASGDILAMKVVT 2052
PR VVL + +GFGF++RG KASS + RP+ + PALQY ++V+ VA AGL+ GDF+L IN V SASHE V +I+++G ++ + VV+
Sbjct: 560 PRSVVLHRAKRGFGFILRGAKASSQLMQLRPSERFPALQYLDDVDPGGVADMAGLRPGDFLLTINGEDVTSASHEQVVEMIRSAGALVNLTVVS 653
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Ensembl Fly
Match: Prosap (gene:FBgn0040752 transcript:FBtr0339765) HSP 1 Score: 218.394 bits (555), Expect = 2.010e-57 Identity = 114/262 (43.51%), Postives = 159/262 (60.69%), Query Frame = 1
Query: 214 IKVPDLNLKKSVSLILTETVGMLKKSLIGTLSNDLKDAMNYGLFIPPTEGKAGKFLQEERPLNDYGLHKVHQIVELRYKRRLYRCTNLNINKLKKLHSKTNLKLFMEHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQ-ACRFGRTHHLEYLLQYRAD 996
I VP+LN+ K + V +K+ ++ +L +LK++ NYGLF PP GKAGKFL EER L DY + +EL+YKRR+Y+ L+ +LK LH++ NL+ F+E + + K++KM KG+DPNF E+G+TPL A +P +L+ LV GGA LDYR +G T LH A +LEAV LL+LG SPN D G+TPLY SI A TE LL D++ +GI+D G E+HQ A G E + Y+++
Sbjct: 24 IHVPELNVYKCLQFPSERLVWDVKQQVLASLPKELKESFNYGLFAPPANGKAGKFLDEERRLGDYPFNGPVGYLELKYKRRVYKMLTLDERQLKALHTRANLRRFLECINGGHVEKIAKMCAKGLDPNFHCSESGDTPLTVATGAKKPNKLLIALVNGGALLDYRTKDGSTALHRAVEHDSLEAVSTLLELGASPNYRDGRGITPLYISITRKCEAKITESLLHDHATLGIQDSQGWNEVHQVAVIAGNLELAEIIENYKSE 285 HSP 2 Score: 95.9005 bits (237), Expect = 1.726e-19 Identity = 45/94 (47.87%), Postives = 65/94 (69.15%), Query Frame = 1
Query: 1774 PRVVVLQKNSQGFGFVIRGLKASSTI-NFRPTLKNPALQYFEEVEVNSVAARAGLKKGDFILEINNLSVVSASHEDTVRLIKASGDILAMKVVT 2052
PR VVL + +GFGF++RG KASS + RP+ + PALQY ++V+ VA AGL+ GDF+L IN V SASHE V +I+++G ++ + VV+
Sbjct: 495 PRSVVLHRAKRGFGFILRGAKASSQLMQLRPSERFPALQYLDDVDPGGVADMAGLRPGDFLLTINGEDVTSASHEQVVEMIRSAGALVNLTVVS 588
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Ensembl Fly
Match: Prosap (gene:FBgn0040752 transcript:FBtr0339764) HSP 1 Score: 218.394 bits (555), Expect = 2.460e-57 Identity = 114/262 (43.51%), Postives = 159/262 (60.69%), Query Frame = 1
Query: 214 IKVPDLNLKKSVSLILTETVGMLKKSLIGTLSNDLKDAMNYGLFIPPTEGKAGKFLQEERPLNDYGLHKVHQIVELRYKRRLYRCTNLNINKLKKLHSKTNLKLFMEHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQ-ACRFGRTHHLEYLLQYRAD 996
I VP+LN+ K + V +K+ ++ +L +LK++ NYGLF PP GKAGKFL EER L DY + +EL+YKRR+Y+ L+ +LK LH++ NL+ F+E + + K++KM KG+DPNF E+G+TPL A +P +L+ LV GGA LDYR +G T LH A +LEAV LL+LG SPN D G+TPLY SI A TE LL D++ +GI+D G E+HQ A G E + Y+++
Sbjct: 24 IHVPELNVYKCLQFPSERLVWDVKQQVLASLPKELKESFNYGLFAPPANGKAGKFLDEERRLGDYPFNGPVGYLELKYKRRVYKMLTLDERQLKALHTRANLRRFLECINGGHVEKIAKMCAKGLDPNFHCSESGDTPLTVATGAKKPNKLLIALVNGGALLDYRTKDGSTALHRAVEHDSLEAVSTLLELGASPNYRDGRGITPLYISITRKCEAKITESLLHDHATLGIQDSQGWNEVHQVAVIAGNLELAEIIENYKSE 285 HSP 2 Score: 95.9005 bits (237), Expect = 1.642e-19 Identity = 45/94 (47.87%), Postives = 65/94 (69.15%), Query Frame = 1
Query: 1774 PRVVVLQKNSQGFGFVIRGLKASSTI-NFRPTLKNPALQYFEEVEVNSVAARAGLKKGDFILEINNLSVVSASHEDTVRLIKASGDILAMKVVT 2052
PR VVL + +GFGF++RG KASS + RP+ + PALQY ++V+ VA AGL+ GDF+L IN V SASHE V +I+++G ++ + VV+
Sbjct: 641 PRSVVLHRAKRGFGFILRGAKASSQLMQLRPSERFPALQYLDDVDPGGVADMAGLRPGDFLLTINGEDVTSASHEQVVEMIRSAGALVNLTVVS 734 HSP 3 Score: 54.6842 bits (130), Expect = 6.711e-7 Identity = 45/172 (26.16%), Postives = 81/172 (47.09%), Query Frame = 1
Query: 751 GNLEAVKILLDLGQSPN-TIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQES-CARLLLFRGADRTVKNRAG-HSAYQQAILSDNKNIAMLIQYYKNEDVVCIRGSPKYNDKRRPSVA 1257
G++E + + G PN + G TPL + + L+ +++ ++G +H+A + LL+ A N + + G TPL+I E+ LL A +++ G + +Q A+++ N +A +I+ YK+ED+V RG P+YN KRR +
Sbjct: 135 GHVEKIAKMCAKGLDPNFHCSESGDTPLTVATGAKKPNKLLIALVNGGALLDYRTKDGSTALHRAVEHDSLEAVSTLLELGASPNYRDGR-GITPLYISITRKCEAKITESLLHDHATLGIQDSQGWNEVHQVAVIAGNLELAEIIENYKSEDIVPFRGPPRYNPKRRSGIG 305
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Ensembl Fly
Match: Ank2 (gene:FBgn0261788 transcript:FBtr0303123) HSP 1 Score: 89.3521 bits (220), Expect = 1.695e-17 Identity = 60/193 (31.09%), Postives = 96/193 (49.74%), Query Frame = 1
Query: 616 GETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIIS--DPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYY 1188
GETPL A Q ++I++L+ GA +D R TPLH A+ LGN++ V +LL G + ++ T L+ + D AA L+ + + + + G +H ++G + LLQ AD+++Q KNG TPLH+ + N + A LLL +GA + GH+ A + +IA + Y
Sbjct: 436 GETPLHLAARANQ-TDIIRILLRNGAQVDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMYTALHIAAKEGQDEVAAV---LIENGAALDAATKKGFTPLHLTAKYGHIKVAQLLLQKEADVDAQ-GKNGVTPLHVACHYNNQQVALLLLEKGASPHATAKNGHTPLHIAARKNQMDIATTLLEY 623 HSP 2 Score: 77.0258 bits (188), Expect = 9.491e-14 Identity = 66/229 (28.82%), Postives = 109/229 (47.60%), Query Frame = 1
Query: 535 HVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAM-LIQYYKNEDVVCIRG 1218
H GN +I + ++ KG D N+ K +PL A + ++ +L+E G +++ + +G TPLH AA G+ + V +LL+ G + + GL PL+ + + A LL+ + + + L +H A G + LL AD N++ + NG TPLHI N+ LLL GA + +G + A NI + L+Q+ + DV +RG
Sbjct: 214 HYGNQNIANL--LIQKGADVNYSAKHNI-SPLHVAAKWGK-TNMVSLLLEKGGNIEAKTRDGLTPLHCAARSGHEQVVDMLLERGAPISAKTKNGLAPLHMAAQGEHVDAA-RILLYHRAPVDEVTVDYLTALHVAAHCGHVRVAKLLLDRNADANAR-ALNGFTPLHIACKKNRLKVVELLLRHGASISATTESGLTPLHVAAFMGCMNIVIYLLQHDASPDVPTVRG 436 HSP 3 Score: 69.707 bits (169), Expect = 1.598e-11 Identity = 44/158 (27.85%), Postives = 84/158 (53.16%), Query Frame = 1
Query: 658 VELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDY-SIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHS 1128
+++ ++L++ A +D + NG TPLH A N + +LL+ G SP+ + G TPL+ + + T L +Y ++ E + G +H + + G L++++A +N +KNG TP+H+CA + + A +L GA+ + +AG++
Sbjct: 548 IKVAQLLLQKEADVDAQGKNGVTPLHVACHYNNQQVALLLLEKGASPHATAKNGHTPLHIAARKNQMDIAT--TLLEYGALANAESKAGFTPLHLSSQEGHAEISNLLIEHKAAVN-HPAKNGLTPMHLCAQEDNVNVAEILEKNGANIDMATKAGYT 702 HSP 4 Score: 60.077 bits (144), Expect = 1.366e-8 Identity = 51/174 (29.31%), Postives = 72/174 (41.38%), Query Frame = 1
Query: 658 VELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLI 1179
V + K+L++ A + R NG TPLH A L+ V++LL G S + + GLTPL H A G + + YLLQ+ A + T + G TPLH+ A NQ R+LL GA + R + A N +I ML+
Sbjct: 350 VRVAKLLLDRNADANARALNGFTPLHIACKKNRLKVVELLLRHGASISATTESGLTPL----------------------------------HVAAFMGCMNIVIYLLQHDASPDVPTVR-GETPLHLAARANQTDIIRILLRNGAQVDARAREQQTPLHIASRLGNVDIVMLL 488 HSP 5 Score: 57.7658 bits (138), Expect = 7.369e-8 Identity = 65/261 (24.90%), Postives = 117/261 (44.83%), Query Frame = 1
Query: 535 HVGNAD--IGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPL-------YHSIIS----------------------DPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYYKNEDVVCIRGSP 1224
H+ + D I VS++L +G + K+ G T L SL E++K+L+E A ++ + NG TPL+ AA + V++LL G + + ++G TPL + +++ D A T L D++ + ++G +H A +G + L+Q AD+N ++K+ +PLH+ A + + LLL +G + K R G + A S ++ + D++ RG+P
Sbjct: 49 HLASKDGHIHVVSELLRRGAIVDSATKK-GNTAL-HIASLAGQEEVVKLLLEHNASVNVQSQNGFTPLYMAAQENHDAVVRLLLSNGANQSLATEDGFTPLAVAMQQGHDKVVAVLLESDTRGKVRLPALHIAAKKDDVKAATLLLDNDHN-PDVTSKSGFTPLHIASHYGNQNIANLLIQKGADVN-YSAKHNISPLHVAAKWGKTNMVSLLLEKGGNIEAKTRDGLTPLHCAARSGHEQVV---------DMLLERGAP 296 HSP 6 Score: 55.8398 bits (133), Expect = 2.630e-7 Identity = 42/146 (28.77%), Postives = 62/146 (42.47%), Query Frame = 1
Query: 616 GETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYL 1053
G TP+ C+ V + ++L + GA++D G+TPLH A+ G V+ LL G + + G TPL HQ + G H + LL+++A+ N+QT NG TPLHI L
Sbjct: 667 GLTPM-HLCAQEDNVNVAEILEKNGANIDMATKAGYTPLHVASHFGQANMVRFLLQNGANVDAATSIGYTPL----------------------------------HQTAQQGHCHIVNLLLEHKANANAQTV-NGQTPLHIARKL 776 HSP 7 Score: 54.299 bits (129), Expect = 8.269e-7 Identity = 52/171 (30.41%), Postives = 82/171 (47.95%), Query Frame = 1
Query: 673 VLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSD-NKNIAMLIQ 1182
++ E GA D G+T AA GNLE V L NT + GL L H D LL +I+ + G +H A G+ ++ LL++ A +N Q S+NG TPL++ A N ++ RLLL GA++++ G + A+ +K +A+L++
Sbjct: 1 MVTENGAQGD-----GNTSFLRAARAGNLERVLEHLKNNIDINTSNANGLNAL-HLASKDGHIHVVSELLRRGAIVDSATKKGNTALHIASLAGQEEVVKLLLEHNASVNVQ-SQNGFTPLYMAAQENHDAVVRLLLSNGANQSLATEDGFTPLAVAMQQGHDKVVAVLLE 164 HSP 8 Score: 53.1434 bits (126), Expect = 1.872e-6 Identity = 44/157 (28.03%), Postives = 70/157 (44.59%), Query Frame = 1
Query: 625 PLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGA 1095
P + + V+ +L++ + D +G TPLH A+ GN +L+ G N + ++PL H LL I + +GL +H A R G ++ LL+ A I+++T KNG PLH+ A AR+LL+ A
Sbjct: 174 PALHIAAKKDDVKAATLLLDNDHNPDVTSKSGFTPLHIASHYGNQNIANLLIQKGADVNYSAKHNISPL-HVAAKWGKTNMVSLLLEKGGNIEAKTRDGLTPLHCAARSGHEQVVDMLLERGAPISAKT-KNGLAPLHMAAQGEHVDAARILLYHRA 328
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Ensembl Zebrafish
Match: shank3b (SH3 and multiple ankyrin repeat domains 3b [Source:ZFIN;Acc:ZDB-GENE-041210-74]) HSP 1 Score: 323.553 bits (828), Expect = 3.026e-91 Identity = 172/378 (45.50%), Postives = 237/378 (62.70%), Query Frame = 1
Query: 166 GSSVATNNNNQCFKFEIKVPDLNLKKSVSLILTETVGMLKKSLIGTLSNDLKDAMNYGLFIPPTEGKAGKFLQEERPLNDYGLHKVHQI--VELRYKRRLYRCTNLNINKLKKLHSKTNLKLFMEHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYYKNEDVVCIRGSPKYNDKRRPSVATSTFLHRSRSAS 1293
GS + + I +PDL K + L L V + K+ ++ TL+ L D +NYGL++P G+AGKFL EER L +Y L V + +E RYKRR+Y ++++ +L KLH+K NLK FME+V + KV + L KG+DPNF ++GE+PL L +LIKVL GGAHLD+R +G T LH AA N A+ LLDLG SP+ D GLTPLYHS + C E LL+D++ +G DENG QEIHQACR G HLE+LL Y A++++Q + +GNT LH+CA NQE CAR+LLFRGA++ +KN +A+Q AI++ N ++A +I+ +K DVV R +P Y+ +RR +V S RSAS
Sbjct: 42 GSEPMEDLHGNAVVIRIGIPDLQQTKCLRLDLEAPVWVCKQRVLVTLTQSLTDVLNYGLYLPAFNGRAGKFLDEERLLREYPLPTVTPVPYLEFRYKRRVYTQSHVDDKQLAKLHTKANLKKFMEYVQQRCVDKVCRFLEKGLDPNFHDSDSGESPLTLVAQLDTCADLIKVLRSGGAHLDFRTRDGLTALHKAAQTHNHVALTTLLDLGASPDYKDSRGLTPLYHSAMVGGDPYCCELLLYDHAQLGYSDENGWQEIHQACRHGNVQHLEHLLFYGAEMSAQNA-SGNTALHLCALYNQEGCARVLLFRGANKEIKNYNNQTAFQVAIIAGNFDLAEIIKIHKTSDVVPFRETPSYSSRRR-AVCVSPRRSLMRSAS 417 HSP 2 Score: 98.9821 bits (245), Expect = 2.330e-20 Identity = 49/95 (51.58%), Postives = 63/95 (66.32%), Query Frame = 1
Query: 1783 VVLQK-NSQGFGFVIRGLKASSTIN-FRPTLKNPALQYFEEVEVNSVAARAGLKKGDFILEINNLSVVSASHEDTVRLIKASGDILAMKVVTVNK 2061
LQK +S+GFGFV+RG KA + I F PT PALQY E V++ VA RAGL+ GDF++E+N +SVV H V LI+ G L MKVV+V +
Sbjct: 600 ATLQKRDSEGFGFVLRGAKAETPIEEFTPTPAFPALQYLESVDLEGVAWRAGLRTGDFLIEVNGVSVVKVGHRQVVSLIRQGGSRLVMKVVSVTR 694
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Ensembl Zebrafish
Match: shank3b (SH3 and multiple ankyrin repeat domains 3b [Source:ZFIN;Acc:ZDB-GENE-041210-74]) HSP 1 Score: 323.168 bits (827), Expect = 3.281e-91 Identity = 172/378 (45.50%), Postives = 237/378 (62.70%), Query Frame = 1
Query: 166 GSSVATNNNNQCFKFEIKVPDLNLKKSVSLILTETVGMLKKSLIGTLSNDLKDAMNYGLFIPPTEGKAGKFLQEERPLNDYGLHKVHQI--VELRYKRRLYRCTNLNINKLKKLHSKTNLKLFMEHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYYKNEDVVCIRGSPKYNDKRRPSVATSTFLHRSRSAS 1293
GS + + I +PDL K + L L V + K+ ++ TL+ L D +NYGL++P G+AGKFL EER L +Y L V + +E RYKRR+Y ++++ +L KLH+K NLK FME+V + KV + L KG+DPNF ++GE+PL L +LIKVL GGAHLD+R +G T LH AA N A+ LLDLG SP+ D GLTPLYHS + C E LL+D++ +G DENG QEIHQACR G HLE+LL Y A++++Q + +GNT LH+CA NQE CAR+LLFRGA++ +KN +A+Q AI++ N ++A +I+ +K DVV R +P Y+ +RR +V S RSAS
Sbjct: 42 GSEPMEDLHGNAVVIRIGIPDLQQTKCLRLDLEAPVWVCKQRVLVTLTQSLTDVLNYGLYLPAFNGRAGKFLDEERLLREYPLPTVTPVPYLEFRYKRRVYTQSHVDDKQLAKLHTKANLKKFMEYVQQRCVDKVCRFLEKGLDPNFHDSDSGESPLTLVAQLDTCADLIKVLRSGGAHLDFRTRDGLTALHKAAQTHNHVALTTLLDLGASPDYKDSRGLTPLYHSAMVGGDPYCCELLLYDHAQLGYSDENGWQEIHQACRHGNVQHLEHLLFYGAEMSAQNA-SGNTALHLCALYNQEGCARVLLFRGANKEIKNYNNQTAFQVAIIAGNFDLAEIIKIHKTSDVVPFRETPSYSSRRR-AVCVSPRRSLMRSAS 417 HSP 2 Score: 98.9821 bits (245), Expect = 2.277e-20 Identity = 49/95 (51.58%), Postives = 63/95 (66.32%), Query Frame = 1
Query: 1783 VVLQK-NSQGFGFVIRGLKASSTIN-FRPTLKNPALQYFEEVEVNSVAARAGLKKGDFILEINNLSVVSASHEDTVRLIKASGDILAMKVVTVNK 2061
LQK +S+GFGFV+RG KA + I F PT PALQY E V++ VA RAGL+ GDF++E+N +SVV H V LI+ G L MKVV+V +
Sbjct: 585 ATLQKRDSEGFGFVLRGAKAETPIEEFTPTPAFPALQYLESVDLEGVAWRAGLRTGDFLIEVNGVSVVKVGHRQVVSLIRQGGSRLVMKVVSVTR 679
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Ensembl Zebrafish
Match: shank3b (SH3 and multiple ankyrin repeat domains 3b [Source:ZFIN;Acc:ZDB-GENE-041210-74]) HSP 1 Score: 322.783 bits (826), Expect = 3.337e-91 Identity = 170/364 (46.70%), Postives = 233/364 (64.01%), Query Frame = 1
Query: 208 FEIKVPDLNLKKSVSLILTETVGMLKKSLIGTLSNDLKDAMNYGLFIPPTEGKAGKFLQEERPLNDYGLHKVHQI--VELRYKRRLYRCTNLNINKLKKLHSKTNLKLFMEHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYYKNEDVVCIRGSPKYNDKRRPSVATSTFLHRSRSAS 1293
I +PDL K + L L V + K+ ++ TL+ L D +NYGL++P G+AGKFL EER L +Y L V + +E RYKRR+Y ++++ +L KLH+K NLK FME+V + KV + L KG+DPNF ++GE+PL L +LIKVL GGAHLD+R +G T LH AA N A+ LLDLG SP+ D GLTPLYHS + C E LL+D++ +G DENG QEIHQACR G HLE+LL Y A++++Q + +GNT LH+CA NQE CAR+LLFRGA++ +KN +A+Q AI++ N ++A +I+ +K DVV R +P Y+ +RR +V S RSAS
Sbjct: 11 IRIGIPDLQQTKCLRLDLEAPVWVCKQRVLVTLTQSLTDVLNYGLYLPAFNGRAGKFLDEERLLREYPLPTVTPVPYLEFRYKRRVYTQSHVDDKQLAKLHTKANLKKFMEYVQQRCVDKVCRFLEKGLDPNFHDSDSGESPLTLVAQLDTCADLIKVLRSGGAHLDFRTRDGLTALHKAAQTHNHVALTTLLDLGASPDYKDSRGLTPLYHSAMVGGDPYCCELLLYDHAQLGYSDENGWQEIHQACRHGNVQHLEHLLFYGAEMSAQNA-SGNTALHLCALYNQEGCARVLLFRGANKEIKNYNNQTAFQVAIIAGNFDLAEIIKIHKTSDVVPFRETPSYSSRRR-AVCVSPRRSLMRSAS 372 HSP 2 Score: 98.9821 bits (245), Expect = 2.428e-20 Identity = 49/95 (51.58%), Postives = 63/95 (66.32%), Query Frame = 1
Query: 1783 VVLQK-NSQGFGFVIRGLKASSTIN-FRPTLKNPALQYFEEVEVNSVAARAGLKKGDFILEINNLSVVSASHEDTVRLIKASGDILAMKVVTVNK 2061
LQK +S+GFGFV+RG KA + I F PT PALQY E V++ VA RAGL+ GDF++E+N +SVV H V LI+ G L MKVV+V +
Sbjct: 534 ATLQKRDSEGFGFVLRGAKAETPIEEFTPTPAFPALQYLESVDLEGVAWRAGLRTGDFLIEVNGVSVVKVGHRQVVSLIRQGGSRLVMKVVSVTR 628
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Ensembl Zebrafish
Match: shank3b (SH3 and multiple ankyrin repeat domains 3b [Source:ZFIN;Acc:ZDB-GENE-041210-74]) HSP 1 Score: 322.398 bits (825), Expect = 4.059e-91 Identity = 170/364 (46.70%), Postives = 233/364 (64.01%), Query Frame = 1
Query: 208 FEIKVPDLNLKKSVSLILTETVGMLKKSLIGTLSNDLKDAMNYGLFIPPTEGKAGKFLQEERPLNDYGLHKVHQI--VELRYKRRLYRCTNLNINKLKKLHSKTNLKLFMEHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYYKNEDVVCIRGSPKYNDKRRPSVATSTFLHRSRSAS 1293
I +PDL K + L L V + K+ ++ TL+ L D +NYGL++P G+AGKFL EER L +Y L V + +E RYKRR+Y ++++ +L KLH+K NLK FME+V + KV + L KG+DPNF ++GE+PL L +LIKVL GGAHLD+R +G T LH AA N A+ LLDLG SP+ D GLTPLYHS + C E LL+D++ +G DENG QEIHQACR G HLE+LL Y A++++Q + +GNT LH+CA NQE CAR+LLFRGA++ +KN +A+Q AI++ N ++A +I+ +K DVV R +P Y+ +RR +V S RSAS
Sbjct: 11 IRIGIPDLQQTKCLRLDLEAPVWVCKQRVLVTLTQSLTDVLNYGLYLPAFNGRAGKFLDEERLLREYPLPTVTPVPYLEFRYKRRVYTQSHVDDKQLAKLHTKANLKKFMEYVQQRCVDKVCRFLEKGLDPNFHDSDSGESPLTLVAQLDTCADLIKVLRSGGAHLDFRTRDGLTALHKAAQTHNHVALTTLLDLGASPDYKDSRGLTPLYHSAMVGGDPYCCELLLYDHAQLGYSDENGWQEIHQACRHGNVQHLEHLLFYGAEMSAQNA-SGNTALHLCALYNQEGCARVLLFRGANKEIKNYNNQTAFQVAIIAGNFDLAEIIKIHKTSDVVPFRETPSYSSRRR-AVCVSPRRSLMRSAS 372 HSP 2 Score: 98.9821 bits (245), Expect = 2.359e-20 Identity = 49/95 (51.58%), Postives = 63/95 (66.32%), Query Frame = 1
Query: 1783 VVLQK-NSQGFGFVIRGLKASSTIN-FRPTLKNPALQYFEEVEVNSVAARAGLKKGDFILEINNLSVVSASHEDTVRLIKASGDILAMKVVTVNK 2061
LQK +S+GFGFV+RG KA + I F PT PALQY E V++ VA RAGL+ GDF++E+N +SVV H V LI+ G L MKVV+V +
Sbjct: 534 ATLQKRDSEGFGFVLRGAKAETPIEEFTPTPAFPALQYLESVDLEGVAWRAGLRTGDFLIEVNGVSVVKVGHRQVVSLIRQGGSRLVMKVVSVTR 628
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Ensembl Zebrafish
Match: shank2b (SH3 and multiple ankyrin repeat domains 2b [Source:ZFIN;Acc:ZDB-GENE-061207-58]) HSP 1 Score: 314.309 bits (804), Expect = 4.420e-88 Identity = 164/374 (43.85%), Postives = 233/374 (62.30%), Query Frame = 1
Query: 214 IKVPDLNLKKSVSLILTETVGMLKKSLIGTLSNDLKDAMNYGLFIPPTEGKAGKFLQEERPLNDYGLHKVHQI--VELRYKRRLYRCTNLNINKLKKLHSKTNLKLFMEHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYYKNEDVVCIRGSPKYNDKRRPSVATSTFLHRSRS---ASRIMDISQVD 1320
+ +PDL KS+ TV + K+ ++ TL+ L+D +NYGLF P +G+ FL+EER L DY L I +E RYK R+Y+ N+N +++KLH++ NL+ FME++ + + KV+KML +G+DPN+ +TGETPL A L +E+I L GGAHLD+R +G T LH AA N A+K +LDLG SP+ D++GLTPLYH++ +C E LL ++ +G DENG EIHQACR+G HLE+LL Y AD++ + + +GNT LHICA QE CAR+LL RGA + VKN G + +Q AI++ N +A I+ +K D+V R +P + RPS S H+ RS A R++ S D
Sbjct: 51 VVIPDLQQSKSMRFSPDATVWVAKQQILCTLTQSLRDVLNYGLFQPAVDGRESGFLEEERLLRDYPLSSTKGIPTLEFRYKSRVYQQPNVNEKQIEKLHTQVNLRKFMEYIQHHQVEKVAKMLERGLDPNYHDPDTGETPLTLAAHLDNMLEIIVTLKNGGAHLDFRSRDGMTALHKAARAKNQIALKTMLDLGASPDYKDRQGLTPLYHTVTVGGDPSCCEVLLRAHASVGCHDENGWHEIHQACRYGHVQHLEHLLFYGADMHVENA-SGNTALHICALYKQEKCARVLLVRGASKDVKNYRGQTPFQVAIIAGNFELAEFIKNHKEADIVPFREAPAGTGRSRPS-QQSPLQHQGRSTLAAPRVLLRSNSD 422 HSP 2 Score: 93.2041 bits (230), Expect = 1.345e-18 Identity = 45/96 (46.88%), Postives = 67/96 (69.79%), Query Frame = 1
Query: 1780 VVVLQKNSQGFGFVIRGLKASSTIN-FRPTLKNPALQYFEEVEVNSVAARAGLKKGDFILEINNLSVVSASHEDTVRLIKASGDILAMKVVTVNKD 2064
VV+ +K+++GFGFV+RG KA + I F PT PALQY E V+ VA +AGL+ GDF++E+N +VV H+ V +I+ G+ L +KVVTV+++
Sbjct: 626 VVLQKKDNEGFGFVLRGAKADTPIEEFTPTPAFPALQYLESVDEGGVAWKAGLRTGDFLIEVNQDNVVKVGHKQVVNMIRHGGNHLIIKVVTVSRN 721
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Ensembl Xenopus
Match: SHANK1 (SH3 and multiple ankyrin repeat domains 1 [Source:HGNC Symbol;Acc:HGNC:15474]) HSP 1 Score: 323.553 bits (828), Expect = 6.054e-91 Identity = 168/377 (44.56%), Postives = 237/377 (62.86%), Query Frame = 1
Query: 172 SVATNNNNQCFKFEIKVPDLNLKKSVSLILTETVGMLKKSLIGTLSNDLKDAMNYGLFIPPTEGKAGKFLQEERPLNDY--GLHKVHQIVELRYKRRLYRCTNLNINKLKKLHSKTNLKLFMEHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYYKNEDVVCIRGSPKYNDKRRP---SVATSTFLHRSRS 1287
SV ++N F I +PDL+ K + T+ + K+ ++ TL+ LKD +NYGLF P T G+ KFL EER L +Y K +E RYK R+Y+ TNL+ +L KLH+K LK F+E+V + KV+++L+KG+DPN+ ETGETPL A L V++I++L GGAH+D+R +G T LH + N A+ LLDLG SPN D+ GLTPLYH+ + C E LL++ + IG DENG QEIHQAC+ G + HLE+LL Y AD SQ + +GNT LHICA N+ESCAR+LL+RGA + +KN +G + +Q A++S N + LI+ +++ DVV + SP Y RR +++ LHR+ S
Sbjct: 67 SVPDDSNFSMMVFRIGIPDLHQTKCLRFNPDATIWVAKQQILCTLNESLKDVLNYGLFQPATNGRDAKFLDEERLLREYPQSFEKGVPYLEFRYKTRVYKQTNLDEKQLAKLHTKAGLKKFVEYVQHGSAEKVARLLDKGLDPNYHDSETGETPLTLASQLEGTVDVIRMLCLGGAHIDFRSRDGMTALHKSVCARNYNALMTLLDLGGSPNHKDRRGLTPLYHTAMVGGDPRCCELLLYNRASIGTVDENGWQEIHQACQHGHSQHLEHLLFYGADPASQNA-SGNTALHICALYNKESCARILLYRGASKDIKNHSGQTPFQVAVISGNFELGELIKSHRDSDVVPFQESPSYAMHRREGGKALSVPHVLHRANS 442 HSP 2 Score: 93.5893 bits (231), Expect = 1.574e-18 Identity = 51/107 (47.66%), Postives = 68/107 (63.55%), Query Frame = 1
Query: 1777 RVVVLQK-NSQGFGFVIRGLKASSTIN-FRPTLKNPALQYFEEVEVNSVAARAGLKKGDFILEINNLSVVSASHEDTVRLIKASGDILAMKVVTV--NKDKLDEQRK 2085
+ V+LQK +S+GFGFV+RG KA + I F PT PALQY E V+ VA RAGL+ GDF++E+N +VV H V +I+ G+ L +KVV V N + D RK
Sbjct: 631 KTVLLQKKDSEGFGFVLRGAKAQTPIEEFTPTPAFPALQYLESVDEGGVAWRAGLRMGDFLIEVNGQNVVKVGHRQVVNMIRQGGNNLMVKVVMVTRNPEMEDAMRK 737
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Ensembl Xenopus
Match: SHANK1 (SH3 and multiple ankyrin repeat domains 1 [Source:HGNC Symbol;Acc:HGNC:15474]) HSP 1 Score: 323.168 bits (827), Expect = 7.028e-91 Identity = 168/377 (44.56%), Postives = 237/377 (62.86%), Query Frame = 1
Query: 172 SVATNNNNQCFKFEIKVPDLNLKKSVSLILTETVGMLKKSLIGTLSNDLKDAMNYGLFIPPTEGKAGKFLQEERPLNDY--GLHKVHQIVELRYKRRLYRCTNLNINKLKKLHSKTNLKLFMEHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYYKNEDVVCIRGSPKYNDKRRP---SVATSTFLHRSRS 1287
SV ++N F I +PDL+ K + T+ + K+ ++ TL+ LKD +NYGLF P T G+ KFL EER L +Y K +E RYK R+Y+ TNL+ +L KLH+K LK F+E+V + KV+++L+KG+DPN+ ETGETPL A L V++I++L GGAH+D+R +G T LH + N A+ LLDLG SPN D+ GLTPLYH+ + C E LL++ + IG DENG QEIHQAC+ G + HLE+LL Y AD SQ + +GNT LHICA N+ESCAR+LL+RGA + +KN +G + +Q A++S N + LI+ +++ DVV + SP Y RR +++ LHR+ S
Sbjct: 67 SVPDDSNFSMMVFRIGIPDLHQTKCLRFNPDATIWVAKQQILCTLNESLKDVLNYGLFQPATNGRDAKFLDEERLLREYPQSFEKGVPYLEFRYKTRVYKQTNLDEKQLAKLHTKAGLKKFVEYVQHGSAEKVARLLDKGLDPNYHDSETGETPLTLASQLEGTVDVIRMLCLGGAHIDFRSRDGMTALHKSVCARNYNALMTLLDLGGSPNHKDRRGLTPLYHTAMVGGDPRCCELLLYNRASIGTVDENGWQEIHQACQHGHSQHLEHLLFYGADPASQNA-SGNTALHICALYNKESCARILLYRGASKDIKNHSGQTPFQVAVISGNFELGELIKSHRDSDVVPFQESPSYAMHRREGGKALSVPHVLHRANS 442 HSP 2 Score: 93.5893 bits (231), Expect = 1.586e-18 Identity = 51/107 (47.66%), Postives = 68/107 (63.55%), Query Frame = 1
Query: 1777 RVVVLQK-NSQGFGFVIRGLKASSTIN-FRPTLKNPALQYFEEVEVNSVAARAGLKKGDFILEINNLSVVSASHEDTVRLIKASGDILAMKVVTV--NKDKLDEQRK 2085
+ V+LQK +S+GFGFV+RG KA + I F PT PALQY E V+ VA RAGL+ GDF++E+N +VV H V +I+ G+ L +KVV V N + D RK
Sbjct: 622 KTVLLQKKDSEGFGFVLRGAKAQTPIEEFTPTPAFPALQYLESVDEGGVAWRAGLRMGDFLIEVNGQNVVKVGHRQVVNMIRQGGNNLMVKVVMVTRNPEMEDAMRK 728
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Ensembl Xenopus
Match: SHANK3 (SH3 and multiple ankyrin repeat domains 3 [Source:NCBI gene;Acc:100488068]) HSP 1 Score: 318.931 bits (816), Expect = 1.525e-89 Identity = 175/389 (44.99%), Postives = 236/389 (60.67%), Query Frame = 1
Query: 214 IKVPDLNLKKSVSLILTETVGMLKKSLIGTLSNDLKDAMNYGLFIPPTEGKAGKFLQEERPLNDY--GLHKVHQIVELRYKRRLYRCTNLNINKLKKLHSKTNLKLFMEHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYYKNEDVVCIRGSPKYNDKRR--PSVATST--FLHRSRSASRIMDISQVDKREDSGFNSQIGHY 1362
I +PDL K + L V + K+ ++ TL++ LKD +NYGLF P G+AGKFL EER L +Y L +E RYKRR+Y + L+ + KLH+K NLK FME++ +I KV+++L +G+DPN+Q +TGE PL A L +L+K+L GGAHLD+R G T LH A N + LLDLG SP+ D GLTPLYHS + C E LL DY+ +G EDENG QEIHQACR+G HLE+LL Y AD+ +Q + +GN+ LH+CA NQESCAR+LLFRGA + ++N +A+Q AI++ N +A +I+ +K D+V R +P Y +RR SV S+ FL RS S D+ NS HY
Sbjct: 13 IGIPDLQQTKCLRLNPDAPVWVAKQRILCTLNHSLKDVLNYGLFQPAFNGRAGKFLDEERLLREYPPSLATPVPYLEFRYKRRVYTQSLLDDKQFAKLHTKGNLKKFMEYIQLQNIEKVTRLLERGLDPNYQDPDTGECPLTLASQLEGGADLVKILRNGGAHLDFRTREGLTALHKAVHYRNHAVLMTLLDLGASPDYKDSRGLTPLYHSAMVGGDPYCCELLLRDYASLGCEDENGWQEIHQACRYGHVQHLEHLLFYGADMRAQNA-SGNSALHLCALYNQESCARVLLFRGASKEIRNFNNQTAFQVAIIAGNFELAEIIKTHKESDIVPFRETPSYTKRRRVVSSVGLSSPRFLQRSAS--------------DNNLNSDGAHY 386 HSP 2 Score: 89.3521 bits (220), Expect = 3.157e-17 Identity = 50/103 (48.54%), Postives = 68/103 (66.02%), Query Frame = 1
Query: 1777 RVVVLQKNS-QGFGFVIRGLKASSTIN-FRPTLKNPALQYFEEVEVNSVAARAGLKKGDFILEINNLSVVSASHEDTVRLIKASGDILAMKVVTVNKDKLDEQ 2079
+V LQK +GFGFV+RG KA + I F PT PALQY E V+V+ VA RAGL+ GDF++E+N ++VV H+ V LI+ G L MKVV+V++ E+
Sbjct: 559 KVARLQKRELEGFGFVLRGAKAETPIEEFTPTPAFPALQYLESVDVDGVAWRAGLRTGDFLIEVNGVNVVKVGHKQVVSLIRQGGSHLTMKVVSVSRKPESEE 661
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Ensembl Xenopus
Match: SHANK3 (SH3 and multiple ankyrin repeat domains 3 [Source:NCBI gene;Acc:100488068]) HSP 1 Score: 318.931 bits (816), Expect = 1.585e-89 Identity = 175/389 (44.99%), Postives = 236/389 (60.67%), Query Frame = 1
Query: 214 IKVPDLNLKKSVSLILTETVGMLKKSLIGTLSNDLKDAMNYGLFIPPTEGKAGKFLQEERPLNDY--GLHKVHQIVELRYKRRLYRCTNLNINKLKKLHSKTNLKLFMEHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYYKNEDVVCIRGSPKYNDKRR--PSVATST--FLHRSRSASRIMDISQVDKREDSGFNSQIGHY 1362
I +PDL K + L V + K+ ++ TL++ LKD +NYGLF P G+AGKFL EER L +Y L +E RYKRR+Y + L+ + KLH+K NLK FME++ +I KV+++L +G+DPN+Q +TGE PL A L +L+K+L GGAHLD+R G T LH A N + LLDLG SP+ D GLTPLYHS + C E LL DY+ +G EDENG QEIHQACR+G HLE+LL Y AD+ +Q + +GN+ LH+CA NQESCAR+LLFRGA + ++N +A+Q AI++ N +A +I+ +K D+V R +P Y +RR SV S+ FL RS S D+ NS HY
Sbjct: 13 IGIPDLQQTKCLRLNPDAPVWVAKQRILCTLNHSLKDVLNYGLFQPAFNGRAGKFLDEERLLREYPPSLATPVPYLEFRYKRRVYTQSLLDDKQFAKLHTKGNLKKFMEYIQLQNIEKVTRLLERGLDPNYQDPDTGECPLTLASQLEGGADLVKILRNGGAHLDFRTREGLTALHKAVHYRNHAVLMTLLDLGASPDYKDSRGLTPLYHSAMVGGDPYCCELLLRDYASLGCEDENGWQEIHQACRYGHVQHLEHLLFYGADMRAQNA-SGNSALHLCALYNQESCARVLLFRGASKEIRNFNNQTAFQVAIIAGNFELAEIIKTHKESDIVPFRETPSYTKRRRVVSSVGLSSPRFLQRSAS--------------DNNLNSDGAHY 386 HSP 2 Score: 89.3521 bits (220), Expect = 3.121e-17 Identity = 50/103 (48.54%), Postives = 68/103 (66.02%), Query Frame = 1
Query: 1777 RVVVLQKNS-QGFGFVIRGLKASSTIN-FRPTLKNPALQYFEEVEVNSVAARAGLKKGDFILEINNLSVVSASHEDTVRLIKASGDILAMKVVTVNKDKLDEQ 2079
+V LQK +GFGFV+RG KA + I F PT PALQY E V+V+ VA RAGL+ GDF++E+N ++VV H+ V LI+ G L MKVV+V++ E+
Sbjct: 542 KVARLQKRELEGFGFVLRGAKAETPIEEFTPTPAFPALQYLESVDVDGVAWRAGLRTGDFLIEVNGVNVVKVGHKQVVSLIRQGGSHLTMKVVSVSRKPESEE 644
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Ensembl Xenopus
Match: SHANK3 (SH3 and multiple ankyrin repeat domains 3 [Source:NCBI gene;Acc:100488068]) HSP 1 Score: 318.546 bits (815), Expect = 1.918e-89 Identity = 175/389 (44.99%), Postives = 236/389 (60.67%), Query Frame = 1
Query: 214 IKVPDLNLKKSVSLILTETVGMLKKSLIGTLSNDLKDAMNYGLFIPPTEGKAGKFLQEERPLNDY--GLHKVHQIVELRYKRRLYRCTNLNINKLKKLHSKTNLKLFMEHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYYKNEDVVCIRGSPKYNDKRR--PSVATST--FLHRSRSASRIMDISQVDKREDSGFNSQIGHY 1362
I +PDL K + L V + K+ ++ TL++ LKD +NYGLF P G+AGKFL EER L +Y L +E RYKRR+Y + L+ + KLH+K NLK FME++ +I KV+++L +G+DPN+Q +TGE PL A L +L+K+L GGAHLD+R G T LH A N + LLDLG SP+ D GLTPLYHS + C E LL DY+ +G EDENG QEIHQACR+G HLE+LL Y AD+ +Q + +GN+ LH+CA NQESCAR+LLFRGA + ++N +A+Q AI++ N +A +I+ +K D+V R +P Y +RR SV S+ FL RS S D+ NS HY
Sbjct: 13 IGIPDLQQTKCLRLNPDAPVWVAKQRILCTLNHSLKDVLNYGLFQPAFNGRAGKFLDEERLLREYPPSLATPVPYLEFRYKRRVYTQSLLDDKQFAKLHTKGNLKKFMEYIQLQNIEKVTRLLERGLDPNYQDPDTGECPLTLASQLEGGADLVKILRNGGAHLDFRTREGLTALHKAVHYRNHAVLMTLLDLGASPDYKDSRGLTPLYHSAMVGGDPYCCELLLRDYASLGCEDENGWQEIHQACRYGHVQHLEHLLFYGADMRAQNA-SGNSALHLCALYNQESCARVLLFRGASKEIRNFNNQTAFQVAIIAGNFELAEIIKTHKESDIVPFRETPSYTKRRRVVSSVGLSSPRFLQRSAS--------------DNNLNSDGAHY 386 HSP 2 Score: 89.3521 bits (220), Expect = 3.154e-17 Identity = 50/103 (48.54%), Postives = 68/103 (66.02%), Query Frame = 1
Query: 1777 RVVVLQKNS-QGFGFVIRGLKASSTIN-FRPTLKNPALQYFEEVEVNSVAARAGLKKGDFILEINNLSVVSASHEDTVRLIKASGDILAMKVVTVNKDKLDEQ 2079
+V LQK +GFGFV+RG KA + I F PT PALQY E V+V+ VA RAGL+ GDF++E+N ++VV H+ V LI+ G L MKVV+V++ E+
Sbjct: 554 KVARLQKRELEGFGFVLRGAKAETPIEEFTPTPAFPALQYLESVDVDGVAWRAGLRTGDFLIEVNGVNVVKVGHKQVVSLIRQGGSHLTMKVVSVSRKPESEE 656
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Ensembl Mouse
Match: Shank3 (SH3 and multiple ankyrin repeat domains 3 [Source:MGI Symbol;Acc:MGI:1930016]) HSP 1 Score: 322.398 bits (825), Expect = 8.561e-91 Identity = 172/364 (47.25%), Postives = 233/364 (64.01%), Query Frame = 1
Query: 214 IKVPDLNLKKSVSLILTETVGMLKKSLIGTLSNDLKDAMNYGLFIPPTEGKAGKFLQEERPLNDY--GLHKVHQIVELRYKRRLYRCTNLNINKLKKLHSKTNLKLFMEHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYYKNEDVVCIRGSPKYNDKRR---PS-VATSTFLHRSRS 1287
+ +PDL K + L T V K+ ++ L++ L+DA+NYGLF PP+ G+AGKFL EER L DY L +E RYKRR+Y ++ + KLH+K NLK FM++V KV+++L+KG+DPNF ++GE PL A L +L+KVL GGAHLD+R +G T +H A N A+ LLDLG SP+ D GLTPLYHS + A C E LL D++ +G DENG QEIHQACRFG HLE+LL Y A++ +Q + +GNT LHICA NQESCAR+LLFRGA++ V+N +A+Q AI++ N +A +I+ +K+ DVV R +P Y +RR PS +A+ L RS S
Sbjct: 13 VGIPDLQQTKCLRLDPTAPVWAAKQRVLCALNHSLQDALNYGLFQPPSRGRAGKFLDEERLLQDYPPNLDTPLPYLEFRYKRRVYAQNLIDDKQFAKLHTKANLKKFMDYVQLHSTDKVARLLDKGLDPNFHDPDSGECPLSLAAQLDNATDLLKVLRNGGAHLDFRTRDGLTAVHCATRQRNAGALTTLLDLGASPDYKDSRGLTPLYHSALGGGDALCCELLLHDHAQLGTTDENGWQEIHQACRFGHVQHLEHLLFYGANMGAQNA-SGNTALHICALYNQESCARVLLFRGANKDVRNYNSQTAFQVAIIAGNFELAEVIKTHKDSDVVPFRETPSYAKRRRLAGPSGLASPRPLQRSAS 375 HSP 2 Score: 90.1225 bits (222), Expect = 1.436e-17 Identity = 49/97 (50.52%), Postives = 67/97 (69.07%), Query Frame = 1
Query: 1777 RVVVLQK-NSQGFGFVIRGLKASSTIN-FRPTLKNPALQYFEEVEVNSVAARAGLKKGDFILEINNLSVVSASHEDTVRLIKASGDILAMKVVTVNK 2061
+V +LQK + +GFGFV+RG KA + I F PT PALQY E V+V VA RAGL+ GDF++E+N ++VV H+ V LI+ G+ L MKVV+V +
Sbjct: 569 KVAILQKRDHEGFGFVLRGAKAETPIEEFTPTPAFPALQYLESVDVEGVAWRAGLRTGDFLIEVNGVNVVKVGHKQVVGLIRQGGNRLVMKVVSVTR 665
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Ensembl Mouse
Match: Shank2 (SH3 and multiple ankyrin repeat domains 2 [Source:MGI Symbol;Acc:MGI:2671987]) HSP 1 Score: 314.309 bits (804), Expect = 4.321e-88 Identity = 165/363 (45.45%), Postives = 234/363 (64.46%), Query Frame = 1
Query: 214 IKVPDLNLKKSVSLILTETVGMLKKSLIGTLSNDLKDAMNYGLFIPPTEGKAGKFLQEERPLNDYGLHKVHQI--VELRYKRRLYRCTNLNINKLKKLHSKTNLKLFMEHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYYKNEDVVCIRGSPKY-NDKRRP--SVATSTFLHRSRS 1287
+ + DL K + TV + K+ ++ TL+ LKD +NYGLF P + G+ GKFL EER L +Y + +E RYK+R+Y+ +NL+ +L +LH+KTNLK FM+H + + K++K+L++G+DPNF ETGETPL A L +E+IK L GGAHLD+R +G T LH AA + N A+K LL+LG SP+ D GLTPLYH+ I C E LL +++ + +DENG EIHQACR+G HLE+LL Y AD+++Q + +GNT LHICA NQ+SCAR+LLFRG ++ +KN + +Q AI++ N +A I+ +K D+V R +P Y N +RRP ++A L RS S
Sbjct: 61 VVIQDLQQTKCIRFNPDATVWVAKQRILCTLNQGLKDVLNYGLFQPASNGRDGKFLDEERLLREYPQPMGPGVPSLEFRYKKRVYKQSNLDEKQLARLHTKTNLKKFMDHAQHRSVEKLAKLLDRGLDPNFHDLETGETPLTLAAQLDDSMEVIKALRNGGAHLDFRSRDGMTALHKAARMRNQVALKTLLELGASPDYKDSYGLTPLYHTAIVGGDPYCCELLLHEHASVCCKDENGWHEIHQACRYGHVQHLEHLLFYGADMSAQNA-SGNTALHICALYNQDSCARVLLFRGGNKELKNYNSQTPFQVAIIAGNFELAEYIKNHKETDIVPFREAPAYSNRRRRPPNTLAAPRVLLRSNS 422 HSP 2 Score: 95.1301 bits (235), Expect = 3.769e-19 Identity = 48/98 (48.98%), Postives = 67/98 (68.37%), Query Frame = 1
Query: 1777 RVVVLQK-NSQGFGFVIRGLKASSTIN-FRPTLKNPALQYFEEVEVNSVAARAGLKKGDFILEINNLSVVSASHEDTVRLIKASGDILAMKVVTVNKD 2064
+ VVLQK +++GFGFV+RG KA + I F PT PALQY E V+ VA +AGL+ GDF++E+NN +VV H V +I+ G+ L +KVVTV ++
Sbjct: 625 KTVVLQKKDNEGFGFVLRGAKADTPIEEFTPTPAFPALQYLESVDEGGVAWQAGLRTGDFLIEVNNENVVKVGHRQVVNMIRQGGNHLILKVVTVTRN 722
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Ensembl Mouse
Match: Shank2 (SH3 and multiple ankyrin repeat domains 2 [Source:MGI Symbol;Acc:MGI:2671987]) HSP 1 Score: 301.212 bits (770), Expect = 3.348e-87 Identity = 158/357 (44.26%), Postives = 225/357 (63.03%), Query Frame = 1
Query: 214 IKVPDLNLKKSVSLILTETVGMLKKSLIGTLSNDLKDAMNYGLFIPPTEGKAGKFLQEERPLNDYGLHKVHQI--VELRYKRRLYRCTNLNINKLKKLHSKTNLKLFMEHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYYKNEDVVCIRGSPKYNDKRRPSVATSTFLHR 1278
+ + DL K + TV + K+ ++ TL+ LKD +NYGLF P + G+ GKFL EER L +Y + +E RYK+R+Y+ +NL+ +L +LH+KTNLK FM+H + + K++K+L++G+DPNF ETGETPL A L +E+IK L GGAHLD+R +G T LH AA + N A+K LL+LG SP+ D GLTPLYH+ I C E LL +++ + +DENG EIHQACR+G HLE+LL Y AD+++Q + +GNT LHICA NQ+SCAR+LLFRG ++ +KN + +Q AI++ N +A I+ +K D+V + + RRP HR
Sbjct: 61 VVIQDLQQTKCIRFNPDATVWVAKQRILCTLNQGLKDVLNYGLFQPASNGRDGKFLDEERLLREYPQPMGPGVPSLEFRYKKRVYKQSNLDEKQLARLHTKTNLKKFMDHAQHRSVEKLAKLLDRGLDPNFHDLETGETPLTLAAQLDDSMEVIKALRNGGAHLDFRSRDGMTALHKAARMRNQVALKTLLELGASPDYKDSYGLTPLYHTAIVGGDPYCCELLLHEHASVCCKDENGWHEIHQACRYGHVQHLEHLLFYGADMSAQNA-SGNTALHICALYNQDSCARVLLFRGGNKELKNYNSQTPFQVAIIAGNFELAEYIKNHKETDIVPLAPT------RRPISGAPPCSHR 410 HSP 2 Score: 95.5153 bits (236), Expect = 2.206e-19 Identity = 46/96 (47.92%), Postives = 66/96 (68.75%), Query Frame = 1
Query: 1780 VVVLQKNSQGFGFVIRGLKASSTIN-FRPTLKNPALQYFEEVEVNSVAARAGLKKGDFILEINNLSVVSASHEDTVRLIKASGDILAMKVVTVNKD 2064
VV+ +K+++GFGFV+RG KA + I F PT PALQY E V+ VA +AGL+ GDF++E+NN +VV H V +I+ G+ L +KVVTV ++
Sbjct: 684 VVLQKKDNEGFGFVLRGAKADTPIEEFTPTPAFPALQYLESVDEGGVAWQAGLRTGDFLIEVNNENVVKVGHRQVVNMIRQGGNHLILKVVTVTRN 779
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Ensembl Mouse
Match: Shank1 (SH3 and multiple ankyrin repeat domains 1 [Source:MGI Symbol;Acc:MGI:3613677]) HSP 1 Score: 309.301 bits (791), Expect = 2.650e-86 Identity = 158/360 (43.89%), Postives = 228/360 (63.33%), Query Frame = 1
Query: 172 SVATNNNNQCFKFEIKVPDLNLKKSVSLILTETVGMLKKSLIGTLSNDLKDAMNYGLFIPPTEGKAGKFLQEERPLNDY--GLHKVHQIVELRYKRRLYRCTNLNINKLKKLHSKTNLKLFMEHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYYKNEDVVCIRGSPKYNDKRR 1245
SV + + F I +PDL+ K + T+ K+ ++ LS L+D +NYGLF P T G+ FL+EER L +Y K +E RYK R+Y+ TNL+ +L KLH+KT LK F+E+V KV+++L+KG+DPN+ ++GETPL A VE+I+ L GGAH+D+R +G T LH AA + A+ LLDLG SPN D+ GLTPL+H+ + C E LL++ + +GI DENG QEIHQAC+ G + HLE+LL Y A+ +Q + +GNT LHICA N+E+CAR+LL+RGA++ VKN G + +Q A+++ N + LI+ ++ +DVV + SPKY +RR
Sbjct: 63 SVPDDAHFSMMVFRIGIPDLHQTKCLRFNPDATIWTAKQQVLCALSESLQDVLNYGLFQPATSGRDANFLEEERLLREYPQSFEKGVPYLEFRYKTRVYKQTNLDEKQLAKLHTKTGLKKFLEYVQLGTSDKVARLLDKGLDPNYHDSDSGETPLTLAAQTEGSVEVIRTLCLGGAHIDFRARDGMTALHKAACARHCLALTALLDLGGSPNYKDRRGLTPLFHTAMVGGDPRCCELLLYNRAQLGIADENGWQEIHQACQRGHSQHLEHLLFYGAEPGAQNA-SGNTALHICALYNKETCARILLYRGANKDVKNNNGQTPFQVAVIAGNFELGELIRNHREQDVVPFQESPKYAARRR 421 HSP 2 Score: 94.7449 bits (234), Expect = 4.980e-19 Identity = 49/103 (47.57%), Postives = 67/103 (65.05%), Query Frame = 1
Query: 1777 RVVVLQK-NSQGFGFVIRGLKASSTIN-FRPTLKNPALQYFEEVEVNSVAARAGLKKGDFILEINNLSVVSASHEDTVRLIKASGDILAMKVVTVNK-DKLDE 2076
+ V+LQK +S+GFGFV+RG KA + I F PT PALQY E V+ VA RAGL+ GDF++E+N +VV H V +I+ G+ L +KVV V + +DE
Sbjct: 662 KTVLLQKKDSEGFGFVLRGAKAQTPIEEFTPTPAFPALQYLESVDEGGVAWRAGLRMGDFLIEVNGQNVVKVGHRQVVNMIRQGGNTLMVKVVMVTRHPDMDE 764
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Ensembl Mouse
Match: Shank1 (SH3 and multiple ankyrin repeat domains 1 [Source:MGI Symbol;Acc:MGI:3613677]) HSP 1 Score: 308.916 bits (790), Expect = 3.054e-86 Identity = 158/360 (43.89%), Postives = 228/360 (63.33%), Query Frame = 1
Query: 172 SVATNNNNQCFKFEIKVPDLNLKKSVSLILTETVGMLKKSLIGTLSNDLKDAMNYGLFIPPTEGKAGKFLQEERPLNDY--GLHKVHQIVELRYKRRLYRCTNLNINKLKKLHSKTNLKLFMEHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYYKNEDVVCIRGSPKYNDKRR 1245
SV + + F I +PDL+ K + T+ K+ ++ LS L+D +NYGLF P T G+ FL+EER L +Y K +E RYK R+Y+ TNL+ +L KLH+KT LK F+E+V KV+++L+KG+DPN+ ++GETPL A VE+I+ L GGAH+D+R +G T LH AA + A+ LLDLG SPN D+ GLTPL+H+ + C E LL++ + +GI DENG QEIHQAC+ G + HLE+LL Y A+ +Q + +GNT LHICA N+E+CAR+LL+RGA++ VKN G + +Q A+++ N + LI+ ++ +DVV + SPKY +RR
Sbjct: 63 SVPDDAHFSMMVFRIGIPDLHQTKCLRFNPDATIWTAKQQVLCALSESLQDVLNYGLFQPATSGRDANFLEEERLLREYPQSFEKGVPYLEFRYKTRVYKQTNLDEKQLAKLHTKTGLKKFLEYVQLGTSDKVARLLDKGLDPNYHDSDSGETPLTLAAQTEGSVEVIRTLCLGGAHIDFRARDGMTALHKAACARHCLALTALLDLGGSPNYKDRRGLTPLFHTAMVGGDPRCCELLLYNRAQLGIADENGWQEIHQACQRGHSQHLEHLLFYGAEPGAQNA-SGNTALHICALYNKETCARILLYRGANKDVKNNNGQTPFQVAVIAGNFELGELIRNHREQDVVPFQESPKYAARRR 421 HSP 2 Score: 94.7449 bits (234), Expect = 5.018e-19 Identity = 49/103 (47.57%), Postives = 67/103 (65.05%), Query Frame = 1
Query: 1777 RVVVLQK-NSQGFGFVIRGLKASSTIN-FRPTLKNPALQYFEEVEVNSVAARAGLKKGDFILEINNLSVVSASHEDTVRLIKASGDILAMKVVTVNK-DKLDE 2076
+ V+LQK +S+GFGFV+RG KA + I F PT PALQY E V+ VA RAGL+ GDF++E+N +VV H V +I+ G+ L +KVV V + +DE
Sbjct: 653 KTVLLQKKDSEGFGFVLRGAKAQTPIEEFTPTPAFPALQYLESVDEGGVAWRAGLRMGDFLIEVNGQNVVKVGHRQVVNMIRQGGNTLMVKVVMVTRHPDMDE 755
BLAST of SH3 and multiple ankyrin repeat domains protein vs. UniProt/SwissProt
Match: sp|Q9BYB0|SHAN3_HUMAN (SH3 and multiple ankyrin repeat domains protein 3 OS=Homo sapiens OX=9606 GN=SHANK3 PE=1 SV=3) HSP 1 Score: 324.709 bits (831), Expect = 9.095e-91 Identity = 173/364 (47.53%), Postives = 233/364 (64.01%), Query Frame = 1
Query: 214 IKVPDLNLKKSVSLILTETVGMLKKSLIGTLSNDLKDAMNYGLFIPPTEGKAGKFLQEERPLNDY--GLHKVHQIVELRYKRRLYRCTNLNINKLKKLHSKTNLKLFMEHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYYKNEDVVCIRGSPKYNDKRR---PS-VATSTFLHRSRS 1287
+ +PDL K + L V K+ ++ L++ L+DA+NYGLF PP+ G+AGKFL EER L +Y L +E RYKRR+Y ++ + KLH+K NLK FM++V KV+++L+KG+DPNF ++GE PL A L +L+KVL GGAHLD+R +G T +H A N A+ LLDLG SP+ D GLTPLYHS + A C E LL D++ +GI DENG QEIHQACRFG HLE+LL Y AD+ +Q + +GNT LHICA NQESCAR+LLFRGA+R V+N +A+Q AI++ N +A +I+ +K+ DVV R +P Y +RR PS +A+ L RS S
Sbjct: 13 VGIPDLQQTKCLRLDPAAPVWAAKQRVLCALNHSLQDALNYGLFQPPSRGRAGKFLDEERLLQEYPPNLDTPLPYLEFRYKRRVYAQNLIDDKQFAKLHTKANLKKFMDYVQLHSTDKVARLLDKGLDPNFHDPDSGECPLSLAAQLDNATDLLKVLKNGGAHLDFRTRDGLTAVHCATRQRNAAALTTLLDLGASPDYKDSRGLTPLYHSALGGGDALCCELLLHDHAQLGITDENGWQEIHQACRFGHVQHLEHLLFYGADMGAQNA-SGNTALHICALYNQESCARVLLFRGANRDVRNYNSQTAFQVAIIAGNFELAEVIKTHKDSDVVPFRETPSYAKRRRLAGPSGLASPRPLQRSAS 375 HSP 2 Score: 90.8929 bits (224), Expect = 5.843e-17 Identity = 50/97 (51.55%), Postives = 67/97 (69.07%), Query Frame = 1
Query: 1777 RVVVLQK-NSQGFGFVIRGLKASSTIN-FRPTLKNPALQYFEEVEVNSVAARAGLKKGDFILEINNLSVVSASHEDTVRLIKASGDILAMKVVTVNK 2061
+V VLQK + +GFGFV+RG KA + I F PT PALQY E V+V VA RAGL+ GDF++E+N ++VV H+ V LI+ G+ L MKVV+V +
Sbjct: 570 KVAVLQKRDHEGFGFVLRGAKAETPIEEFTPTPAFPALQYLESVDVEGVAWRAGLRTGDFLIEVNGVNVVKVGHKQVVALIRQGGNRLVMKVVSVTR 666
BLAST of SH3 and multiple ankyrin repeat domains protein vs. UniProt/SwissProt
Match: sp|Q4ACU6|SHAN3_MOUSE (SH3 and multiple ankyrin repeat domains protein 3 OS=Mus musculus OX=10090 GN=Shank3 PE=1 SV=3) HSP 1 Score: 322.398 bits (825), Expect = 5.988e-90 Identity = 172/364 (47.25%), Postives = 233/364 (64.01%), Query Frame = 1
Query: 214 IKVPDLNLKKSVSLILTETVGMLKKSLIGTLSNDLKDAMNYGLFIPPTEGKAGKFLQEERPLNDY--GLHKVHQIVELRYKRRLYRCTNLNINKLKKLHSKTNLKLFMEHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYYKNEDVVCIRGSPKYNDKRR---PS-VATSTFLHRSRS 1287
+ +PDL K + L T V K+ ++ L++ L+DA+NYGLF PP+ G+AGKFL EER L DY L +E RYKRR+Y ++ + KLH+K NLK FM++V KV+++L+KG+DPNF ++GE PL A L +L+KVL GGAHLD+R +G T +H A N A+ LLDLG SP+ D GLTPLYHS + A C E LL D++ +G DENG QEIHQACRFG HLE+LL Y A++ +Q + +GNT LHICA NQESCAR+LLFRGA++ V+N +A+Q AI++ N +A +I+ +K+ DVV R +P Y +RR PS +A+ L RS S
Sbjct: 13 VGIPDLQQTKCLRLDPTAPVWAAKQRVLCALNHSLQDALNYGLFQPPSRGRAGKFLDEERLLQDYPPNLDTPLPYLEFRYKRRVYAQNLIDDKQFAKLHTKANLKKFMDYVQLHSTDKVARLLDKGLDPNFHDPDSGECPLSLAAQLDNATDLLKVLRNGGAHLDFRTRDGLTAVHCATRQRNAGALTTLLDLGASPDYKDSRGLTPLYHSALGGGDALCCELLLHDHAQLGTTDENGWQEIHQACRFGHVQHLEHLLFYGANMGAQNA-SGNTALHICALYNQESCARVLLFRGANKDVRNYNSQTAFQVAIIAGNFELAEVIKTHKDSDVVPFRETPSYAKRRRLAGPSGLASPRPLQRSAS 375 HSP 2 Score: 90.1225 bits (222), Expect = 1.004e-16 Identity = 49/97 (50.52%), Postives = 67/97 (69.07%), Query Frame = 1
Query: 1777 RVVVLQK-NSQGFGFVIRGLKASSTIN-FRPTLKNPALQYFEEVEVNSVAARAGLKKGDFILEINNLSVVSASHEDTVRLIKASGDILAMKVVTVNK 2061
+V +LQK + +GFGFV+RG KA + I F PT PALQY E V+V VA RAGL+ GDF++E+N ++VV H+ V LI+ G+ L MKVV+V +
Sbjct: 569 KVAILQKRDHEGFGFVLRGAKAETPIEEFTPTPAFPALQYLESVDVEGVAWRAGLRTGDFLIEVNGVNVVKVGHKQVVGLIRQGGNRLVMKVVSVTR 665
BLAST of SH3 and multiple ankyrin repeat domains protein vs. UniProt/SwissProt
Match: sp|Q9JLU4|SHAN3_RAT (SH3 and multiple ankyrin repeat domains protein 3 OS=Rattus norvegicus OX=10116 GN=Shank3 PE=1 SV=3) HSP 1 Score: 322.398 bits (825), Expect = 6.377e-90 Identity = 172/364 (47.25%), Postives = 233/364 (64.01%), Query Frame = 1
Query: 214 IKVPDLNLKKSVSLILTETVGMLKKSLIGTLSNDLKDAMNYGLFIPPTEGKAGKFLQEERPLNDY--GLHKVHQIVELRYKRRLYRCTNLNINKLKKLHSKTNLKLFMEHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYYKNEDVVCIRGSPKYNDKRR---PS-VATSTFLHRSRS 1287
+ +PDL K + L T V K+ ++ L++ L+DA+NYGLF PP+ G+AGKFL EER L DY L +E RYKRR+Y ++ + KLH+K NLK FM++V KV+++L+KG+DPNF ++GE PL A L +L+KVL GGAHLD+R +G T +H A N A+ LLDLG SP+ D GLTPLYHS + A C E LL D++ +G DENG QEIHQACRFG HLE+LL Y A++ +Q + +GNT LHICA NQESCAR+LLFRGA++ V+N +A+Q AI++ N +A +I+ +K+ DVV R +P Y +RR PS +A+ L RS S
Sbjct: 13 VGIPDLQQTKCLRLDPTAPVWAAKQRVLCALNHSLQDALNYGLFQPPSRGRAGKFLDEERLLQDYPPNLDTPLPYLEFRYKRRVYAQNLIDDKQFAKLHTKANLKKFMDYVQLHSTDKVARLLDKGLDPNFHDPDSGECPLSLAAQLDNATDLLKVLRNGGAHLDFRTRDGLTAVHCATRQRNAGALTTLLDLGASPDYKDSRGLTPLYHSALGGGDALCCELLLHDHAQLGTTDENGWQEIHQACRFGHVQHLEHLLFYGANMGAQNA-SGNTALHICALYNQESCARVLLFRGANKDVRNYNSQTAFQVAIIAGNFELAEVIKTHKDSDVVPFRETPSYAKRRRLAGPSGLASPRPLQRSAS 375 HSP 2 Score: 88.5817 bits (218), Expect = 2.802e-16 Identity = 48/97 (49.48%), Postives = 67/97 (69.07%), Query Frame = 1
Query: 1777 RVVVLQK-NSQGFGFVIRGLKASSTIN-FRPTLKNPALQYFEEVEVNSVAARAGLKKGDFILEINNLSVVSASHEDTVRLIKASGDILAMKVVTVNK 2061
+V +LQK + +GFGFV+RG KA + I F PT PALQY E V+V VA +AGL+ GDF++E+N ++VV H+ V LI+ G+ L MKVV+V +
Sbjct: 569 KVAILQKRDHEGFGFVLRGAKAETPIEEFTPTPAFPALQYLESVDVEGVAWKAGLRTGDFLIEVNGVNVVKVGHKQVVGLIRQGGNRLVMKVVSVTR 665
BLAST of SH3 and multiple ankyrin repeat domains protein vs. UniProt/SwissProt
Match: sp|Q9Y566|SHAN1_HUMAN (SH3 and multiple ankyrin repeat domains protein 1 OS=Homo sapiens OX=9606 GN=SHANK1 PE=1 SV=2) HSP 1 Score: 311.612 bits (797), Expect = 3.085e-86 Identity = 160/360 (44.44%), Postives = 228/360 (63.33%), Query Frame = 1
Query: 172 SVATNNNNQCFKFEIKVPDLNLKKSVSLILTETVGMLKKSLIGTLSNDLKDAMNYGLFIPPTEGKAGKFLQEERPLNDY--GLHKVHQIVELRYKRRLYRCTNLNINKLKKLHSKTNLKLFMEHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYYKNEDVVCIRGSPKYNDKRR 1245
SV + + F I +PDL+ K + T+ K+ ++ LS L+D +NYGLF P T G+ FL+EER L +Y K +E RYK R+Y+ TNL+ +L KLH+KT LK F+E+V KV+++L+KG+DPN+ ++GETPL A VE+I+ L GGAH+D+R +G T LH AA + A+ LLDLG SPN D+ GLTPL+H+ + C E LLF+ + +GI DENG QEIHQAC+ G + HLE+LL Y A+ +Q + +GNT LHICA N+E+CAR+LL+RGAD+ VKN G + +Q A+++ N + LI+ ++ +DVV + SPKY +RR
Sbjct: 63 SVPDDAHFSMMVFRIGIPDLHQTKCLRFNPDATIWTAKQQVLCALSESLQDVLNYGLFQPATSGRDANFLEEERLLREYPQSFEKGVPYLEFRYKTRVYKQTNLDEKQLAKLHTKTGLKKFLEYVQLGTSDKVARLLDKGLDPNYHDSDSGETPLTLAAQTEGSVEVIRTLCLGGAHIDFRARDGMTALHKAACARHCLALTALLDLGGSPNYKDRRGLTPLFHTAMVGGDPRCCELLLFNRAQLGIADENGWQEIHQACQRGHSQHLEHLLFYGAEPGAQNA-SGNTALHICALYNKETCARILLYRGADKDVKNNNGQTPFQVAVIAGNFELGELIRNHREQDVVPFQESPKYAARRR 421 HSP 2 Score: 94.7449 bits (234), Expect = 4.088e-18 Identity = 49/103 (47.57%), Postives = 67/103 (65.05%), Query Frame = 1
Query: 1777 RVVVLQK-NSQGFGFVIRGLKASSTIN-FRPTLKNPALQYFEEVEVNSVAARAGLKKGDFILEINNLSVVSASHEDTVRLIKASGDILAMKVVTVNKDK-LDE 2076
+ V+LQK +S+GFGFV+RG KA + I F PT PALQY E V+ VA RAGL+ GDF++E+N +VV H V +I+ G+ L +KVV V + +DE
Sbjct: 662 KTVLLQKKDSEGFGFVLRGAKAQTPIEEFTPTPAFPALQYLESVDEGGVAWRAGLRMGDFLIEVNGQNVVKVGHRQVVNMIRQGGNTLMVKVVMVTRHPDMDE 764
BLAST of SH3 and multiple ankyrin repeat domains protein vs. UniProt/SwissProt
Match: sp|D3YZU1|SHAN1_MOUSE (SH3 and multiple ankyrin repeat domains protein 1 OS=Mus musculus OX=10090 GN=Shank1 PE=1 SV=1) HSP 1 Score: 309.301 bits (791), Expect = 1.854e-85 Identity = 158/360 (43.89%), Postives = 228/360 (63.33%), Query Frame = 1
Query: 172 SVATNNNNQCFKFEIKVPDLNLKKSVSLILTETVGMLKKSLIGTLSNDLKDAMNYGLFIPPTEGKAGKFLQEERPLNDY--GLHKVHQIVELRYKRRLYRCTNLNINKLKKLHSKTNLKLFMEHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYYKNEDVVCIRGSPKYNDKRR 1245
SV + + F I +PDL+ K + T+ K+ ++ LS L+D +NYGLF P T G+ FL+EER L +Y K +E RYK R+Y+ TNL+ +L KLH+KT LK F+E+V KV+++L+KG+DPN+ ++GETPL A VE+I+ L GGAH+D+R +G T LH AA + A+ LLDLG SPN D+ GLTPL+H+ + C E LL++ + +GI DENG QEIHQAC+ G + HLE+LL Y A+ +Q + +GNT LHICA N+E+CAR+LL+RGA++ VKN G + +Q A+++ N + LI+ ++ +DVV + SPKY +RR
Sbjct: 63 SVPDDAHFSMMVFRIGIPDLHQTKCLRFNPDATIWTAKQQVLCALSESLQDVLNYGLFQPATSGRDANFLEEERLLREYPQSFEKGVPYLEFRYKTRVYKQTNLDEKQLAKLHTKTGLKKFLEYVQLGTSDKVARLLDKGLDPNYHDSDSGETPLTLAAQTEGSVEVIRTLCLGGAHIDFRARDGMTALHKAACARHCLALTALLDLGGSPNYKDRRGLTPLFHTAMVGGDPRCCELLLYNRAQLGIADENGWQEIHQACQRGHSQHLEHLLFYGAEPGAQNA-SGNTALHICALYNKETCARILLYRGANKDVKNNNGQTPFQVAVIAGNFELGELIRNHREQDVVPFQESPKYAARRR 421 HSP 2 Score: 94.7449 bits (234), Expect = 3.484e-18 Identity = 49/103 (47.57%), Postives = 67/103 (65.05%), Query Frame = 1
Query: 1777 RVVVLQK-NSQGFGFVIRGLKASSTIN-FRPTLKNPALQYFEEVEVNSVAARAGLKKGDFILEINNLSVVSASHEDTVRLIKASGDILAMKVVTVNK-DKLDE 2076
+ V+LQK +S+GFGFV+RG KA + I F PT PALQY E V+ VA RAGL+ GDF++E+N +VV H V +I+ G+ L +KVV V + +DE
Sbjct: 662 KTVLLQKKDSEGFGFVLRGAKAQTPIEEFTPTPAFPALQYLESVDEGGVAWRAGLRMGDFLIEVNGQNVVKVGHRQVVNMIRQGGNTLMVKVVMVTRHPDMDE 764
BLAST of SH3 and multiple ankyrin repeat domains protein vs. TrEMBL
Match: A0A0X3NM37 (Uncharacterized protein (Fragment) OS=Schistocephalus solidus OX=70667 GN=TR119481 PE=4 SV=1) HSP 1 Score: 431.409 bits (1108), Expect = 1.168e-128 Identity = 208/377 (55.17%), Postives = 272/377 (72.15%), Query Frame = 1
Query: 175 VATNNNNQCFKFEIKVPDLNLKKSVSLILTETVGMLKKSLIGTLSNDLKDAMNYGLFIPPTEGKAGKFLQEERPLNDYGLHKVHQIVELRYKRRLYRCTNLNINKLKKLHSKTNLKLFMEHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYYKNEDVVCIRGSPKYNDKRRPSVATSTFLHRSRSASRIMD 1305
VA+++ F +I VP +NL+K S TE + +K ++I L D ++ NYGLF+PP GKAGKFLQE+R L DY +E +YK+R+YR N+NKL+KL+SK+N++ F+ V ++ KVS++L KGIDPN Q +ETGETPL A L +P ELI LV GGAHLDYR S+ TP+H AA+ GN A+K+LLDLGQSPNT D GLTPLYH++++D +A C ERLL+D+SI+G+ DE GL+EIHQACRFGR HLE L+ Y ADINSQT+ NGNTPLH CAY E+C RLLLFRGADR++KNRAGH+AYQ+A+L+D+ + A LI+ ++ EDVV +RGSPK N +RRP V+ RS S R+ D
Sbjct: 19 VASSSGGIAF-IKIIVPSVNLEKVYSFQPTEVISDIKAAVITDLCLDFREIFNYGLFLPPNNGKAGKFLQEDRLLKDYPFPASVGHLEFKYKQRIYRNLPTNVNKLRKLNSKSNVRQFLALVKYGEVEKVSRLLEKGIDPNIQCRETGETPLTLAVQLPKPKELIMALVAGGAHLDYRASDNRTPIHRAAMCGNFIAIKVLLDLGQSPNTRDSAGLTPLYHTMLNDTSAMCVERLLYDHSILGVTDEAGLEEIHQACRFGRVQHLEQLIAYGADINSQTTFNGNTPLHFCAYNGHEACGRLLLFRGADRSLKNRAGHTAYQEAVLADHASTAALIRDFREEDVVLMRGSPKLNTQRRP-VSQLRLGQRSTSMGRLAD 393 HSP 2 Score: 98.2117 bits (243), Expect = 7.184e-17 Identity = 46/104 (44.23%), Postives = 75/104 (72.12%), Query Frame = 1
Query: 1747 LVDIDTSFLPRVVVLQKNSQGFGFVIRGLKASSTINFRPTLKNPALQYFEEVEVNSVAARAGLKKGDFILEINNLSVVSASHEDTVRLIKASGDILAMKVVTVN 2058
++D+D + LPRV+VLQK ++G+GFV++ + + + F PT++ P+L Y VE N+VA RA L+ GDFILE+NN V + H+ V I+ SG++L++KV+T++
Sbjct: 577 ILDMDWNSLPRVIVLQKGNRGYGFVVQSKRVTGGV-FCPTIEIPSLHYLGHVEENNVAYRANLRPGDFILEVNNNVVTTLPHQAVVDEIRNSGEMLSLKVITID 679
BLAST of SH3 and multiple ankyrin repeat domains protein vs. TrEMBL
Match: A0A5J4P261 (SH3 and multiple ankyrin repeat domains protein OS=Paragonimus westermani OX=34504 GN=DEA37_0013548 PE=4 SV=1) HSP 1 Score: 427.172 bits (1097), Expect = 2.250e-126 Identity = 210/384 (54.69%), Postives = 275/384 (71.61%), Query Frame = 1
Query: 196 QCFKF-EIKVPDLNLKKSVSLILTETVGMLKKSLIGTLSNDLKDAMNYGLFIPPTEGKAGKFLQEERPLNDYGLHKVHQIVELRYKRRLYRCTNLNINKLKKLHSKTNLKLFMEHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVK-----------ILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYYKNEDVVCIRGSPKYNDKRRPSVATSTFLHRSRSASRIMDIS 1311
Q F F + +LNL+++ + T+ + +K S++ +S +KD N+GLF+PP++GKAGKFLQE+R L +Y +EL+YK+R+YR N+NKLKKLH K+NL+ F++ V + ++ +VSK LNKGIDPNF KE+GETPL A L +P E+I LV GGAHLD+R + TPLH AA GN EA+K +LLDLGQSPNT DQ LTPLY+++I+D A C ERLL+D+SI+G DE GLQEIHQACRFGR HLE L+ Y ADINSQTSKNGNTPLHICA+ QE+CARLLLFRGA+RT+ NRAGH+AYQQAILS++ ++A LI+ ++N+DVV IRG PK N++RR S + + R S R+ D S
Sbjct: 22 QSFIFIRVTSSELNLERTFNFNSTDLIFDVKLSVLSGISQPVKDKWNFGLFLPPSKGKAGKFLQEDRMLKEYPFDNSVGHLELKYKQRVYRVLRTNVNKLKKLHIKSNLRQFLDSVKSGNVDRVSKWLNKGIDPNFHWKESGETPLTVAAKLEKPKEMIMTLVAGGAHLDFRAEDTMTPLHRAAATGNYEAIKLVQTNLPHSRQVLLDLGQSPNTRDQYDLTPLYYAVINDTIALCAERLLYDHSILGTTDEAGLQEIHQACRFGRVQHLETLIAYGADINSQTSKNGNTPLHICAFTGQEACARLLLFRGAERTLVNRAGHTAYQQAILSEHSSVAELIKNFQNKDVVPIRGVPKRNERRR-SFSRARLQQRCASLGRLADYS 404 HSP 2 Score: 120.939 bits (302), Expect = 8.156e-24 Identity = 55/109 (50.46%), Postives = 82/109 (75.23%), Query Frame = 1
Query: 1741 SGLVDIDTSFLPRVVVLQKNSQGFGFVIRGLKASSTINFRPTLKNPALQYFEEVEVNSVAARAGLKKGDFILEINNLSVVSASHEDTVRLIKASGDILAMKVVTVNKDK 2067
+ ++D+DT+ LPR++VLQK +GFGFV+RG + F+P+L+ PALQY E+++ S A RA LK GD+ILE+N +V + SHE V+LI++SGDIL+MKV+TV+ +
Sbjct: 594 ASILDLDTTNLPRMIVLQKGPRGFGFVVRGRRGVPG-EFQPSLEVPALQYLEKIDAGSAADRASLKPGDYILEVNGTNVTTMSHEAVVQLIRSSGDILSMKVITVSSSQ 701
BLAST of SH3 and multiple ankyrin repeat domains protein vs. TrEMBL
Match: A0A158QGF4 (Uncharacterized protein OS=Rodentolepis nana OX=102285 GN=HNAJ_LOCUS9 PE=4 SV=1) HSP 1 Score: 417.542 bits (1072), Expect = 2.142e-124 Identity = 195/363 (53.72%), Postives = 267/363 (73.55%), Query Frame = 1
Query: 211 EIKVPDLNLKKSVSLILTETVGMLKKSLIGTLSNDLKDAMNYGLFIPPTEGKAGKFLQEERPLNDYGLHKVHQIVELRYKRRLYRCTNLNINKLKKLHSKTNLKLFMEHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYYKNEDVVCIRGSPKYNDKRRPSVATSTFLHRSRSASRI 1299
+I VP +N++K + I ++ + +K S+I L+ + +D +NYGLF+PPT+GKAGKFLQE+R L +Y EL+YK+R+YR +N++KL+K++SK L+ F+ HV ++ K++K+L+KG+DPNFQ ++ GETPL A L +P +I LV GGAHLD+R ++ TPLH AAI GN EA+ +LLDLGQSPN D GLTPLYH I++D +A C ERLL+D+SI+G+ D G+QEIHQACRFGR HLE L+ Y ADINSQT+ +GNTPLH CAY QESCARLLLFRGA+RT+KNRAGH+A Q+AIL+++ A LI ++++DVV +RGSPKYN +RR + + T R S R+
Sbjct: 30 KISVPSVNIEKVYNFIPSDVISDVKDSIIKDLNLEFRDILNYGLFLPPTDGKAGKFLQEDRQLKEYPFTSSVGYFELKYKQRIYRNLPVNVSKLRKINSKATLRQFLSHVRFGELDKINKLLDKGVDPNFQNRDDGETPLTVAVRLPKPKSIIMALVAGGAHLDFRSADSCTPLHKAAINGNYEAIMVLLDLGQSPNVRDSNGLTPLYHCILNDTSAMCVERLLYDHSILGVVDGAGMQEIHQACRFGRGQHLEQLIAYGADINSQTTFDGNTPLHFCAYNGQESCARLLLFRGANRTLKNRAGHTAQQEAILANHSTTAALIWDFQDKDVVPLRGSPKYNQRRRQNSVSRTLGQRCASLGRL 392 HSP 2 Score: 106.686 bits (265), Expect = 2.089e-19 Identity = 52/104 (50.00%), Postives = 74/104 (71.15%), Query Frame = 1
Query: 1744 GLVDIDTSFLPRVVVLQKNSQGFGFVIRGLKASSTINFRPTLKNPALQYFEEVEVNSVAARAGLKKGDFILEINNLSVVSASHEDTVRLIKASGDILAMKVVTV 2055
G++ +DT FLPRV+VLQK +GFGFV++ KA+ I F PT + P+L Y VE N+VA RA L D+ILE+N V + SH++ V +I+ SGD+L++KVVT+
Sbjct: 554 GILSVDTKFLPRVIVLQKGQRGFGFVVQSKKATRGI-FVPTEEIPSLHYLGHVEENNVAHRANLLPHDYILEVNGDDVATLSHQEVVEMIRDSGDMLSLKVVTL 656
BLAST of SH3 and multiple ankyrin repeat domains protein vs. TrEMBL
Match: A0A4S2LGN5 (ANK_REP_REGION domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_007411 PE=4 SV=1) HSP 1 Score: 392.504 bits (1007), Expect = 6.773e-123 Identity = 189/338 (55.92%), Postives = 249/338 (73.67%), Query Frame = 1
Query: 208 FEIKVPDLNLKKSVSLILTETVGMLKKSLIGTLSNDLKDAMNYGLFIPPTEGKAGKFLQEERPLNDYGLHKVHQIVELRYKRRLYRCTNLNINKLKKLHSKTNLKLFMEHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYYKNEDVVCIRGS 1221
I P+L ++ S + +K S++ +S +KD N+GLF+PP++GKAGKFLQE+R L +Y +EL+YK+R+YR N+NKLKKLH K+NL+ F+++V N + KV+K LNKG+DPNFQ K+ GETPL A L +P ++I LV GGAHLDYR ++ TPLH AA+ GN EA+K+LLDLGQSPNT DQ LTPLY+++++D A C ERLL+D+S +G DE GLQEIHQACRFGR HLE L+ Y ADINSQTSKNGNTPLHICA+ QE+CARLLLFRGADR + NRAGH+AYQQA+LS+++ +A I+ ++++DV I S
Sbjct: 34 IRITCPELGVEGIHSFSPDAIIYDVKISVLKEISQPIKDKWNFGLFLPPSKGKAGKFLQEDRTLREYPFENSVGHLELKYKQRVYRVLKTNVNKLKKLHIKSNLRQFLDNVKNGECDKVTKWLNKGLDPNFQWKDMGETPLTLAIKLAKPRDMIMTLVSGGAHLDYRAADTMTPLHKAAVAGNYEAIKVLLDLGQSPNTKDQYNLTPLYYAVLNDTRAVCVERLLYDHSTLGTADEAGLQEIHQACRFGRVLHLETLITYGADINSQTSKNGNTPLHICAFTGQEACARLLLFRGADRKLLNRAGHTAYQQAVLSEHQAVADEIKNFQDKDVGLIDTS 371
BLAST of SH3 and multiple ankyrin repeat domains protein vs. TrEMBL
Match: A0A183SK35 (ANK_REP_REGION domain-containing protein OS=Schistocephalus solidus OX=70667 GN=SSLN_LOCUS4583 PE=4 SV=1) HSP 1 Score: 390.193 bits (1001), Expect = 1.421e-122 Identity = 184/323 (56.97%), Postives = 240/323 (74.30%), Query Frame = 1
Query: 235 LKKSVSLILTETVGMLKKSLIGTLSNDLKDAMNYGLFIPPTEGKAGKFLQEERPLNDYGLHKVHQIVELRYKRRLYRCTNLNINKLKKLHSKTNLKLFMEHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYYKNEDV 1203
++K S TE + +K ++I L D ++ NYGLF+PP GKAGKFLQE+R L DY +E +YK+R+YR N+NKL+KL+SK+N++ F+ V ++ KVS++L KGIDPN Q +ETGETPL A L +P ELI LV GGAHLDYR S+ TP+H AA+ GN A+K+LLDLGQSPNT D GLTPLYH++++D +A C ERLL+D+SI+G+ DE GL+EIHQACRFGR HLE L+ Y ADINSQT+ NGNTPLH CAY E+C RLLLFRGADR++KNRAGH+AYQ+A+L+D+ + A LI+ ++ EDV
Sbjct: 1 MEKVYSFQPTEVISDIKAAVITDLCLDFREIFNYGLFLPPNNGKAGKFLQEDRLLKDYPFPASVGHLEFKYKQRIYRNLPTNVNKLRKLNSKSNVRQFLALVKYGEVEKVSRLLEKGIDPNIQCRETGETPLTLAVQLPKPKELIMALVAGGAHLDYRASDNRTPIHRAAMCGNFIAIKVLLDLGQSPNTRDSAGLTPLYHTMLNDTSAMCVERLLYDHSILGVTDEAGLEEIHQACRFGRVQHLEQLIAYGADINSQTTFNGNTPLHFCAYNGHEACGRLLLFRGADRSLKNRAGHTAYQEAVLADHASTAALIRDFREEDV 323
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Ensembl Cavefish
Match: shank3b (SH3 and multiple ankyrin repeat domains protein 3-like [Source:NCBI gene;Acc:103038576]) HSP 1 Score: 323.939 bits (829), Expect = 1.519e-91 Identity = 170/364 (46.70%), Postives = 234/364 (64.29%), Query Frame = 1
Query: 208 FEIKVPDLNLKKSVSLILTETVGMLKKSLIGTLSNDLKDAMNYGLFIPPTEGKAGKFLQEERPLNDYGLHKVHQI--VELRYKRRLYRCTNLNINKLKKLHSKTNLKLFMEHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYYKNEDVVCIRGSPKYNDKRRPSVATSTFLHRSRSAS 1293
I +PDL K + L L V + K+ ++ TL+ L D +NYGL++P G+AGKFL EER L +Y L V + +E RYKRR+Y ++++ +L KLH+K NLK FME+V ++ KV + L KG+DPNF ++GE+PL A L +LIK+L GGAHLD+R +G T LH A N A+ LLDLG SP+ D GLTPLYHS + C E LL+D++ +G DENG QEIHQACR G HLE+LL Y A++++Q + +GNT LH+CA NQ+SCAR+LLFRGA++ +KN +A+Q AI++ N ++A +I+ +K DVV R SP Y+ +RR V S RSAS
Sbjct: 57 IRIGIPDLQQTKCLRLDLEAPVWVCKQRVLVTLTQSLTDVLNYGLYLPAFNGRAGKFLDEERLLREYPLPTVTPVPYLEFRYKRRVYTQSHVDDKQLAKLHTKANLKKFMEYVQQRNVEKVCRFLEKGLDPNFHDTDSGESPLTLAAQLDSSADLIKILRSGGAHLDFRTRDGITALHKAVQTHNDVALTTLLDLGASPDYKDSRGLTPLYHSAMVGGDPYCCELLLYDHAQLGYSDENGWQEIHQACRHGNVQHLEHLLFYGAEMSAQNA-SGNTALHLCALYNQDSCARVLLFRGANKEIKNYNNQTAFQVAIIAGNFDLAEIIKIHKTSDVVPFRESPSYSSRRR-GVCVSPRRSLMRSAS 418 HSP 2 Score: 98.5969 bits (244), Expect = 2.848e-20 Identity = 49/95 (51.58%), Postives = 64/95 (67.37%), Query Frame = 1
Query: 1783 VVLQK-NSQGFGFVIRGLKASSTIN-FRPTLKNPALQYFEEVEVNSVAARAGLKKGDFILEINNLSVVSASHEDTVRLIKASGDILAMKVVTVNK 2061
LQK +S+GFGFV+RG KA + I F PT PALQY E V++ VA RAGL+ GDF++E+N +SVV H V LI+ G L MKVV+V++
Sbjct: 599 ATLQKRDSEGFGFVLRGAKAETPIEEFTPTPAFPALQYLESVDLEGVAWRAGLRTGDFLIEVNGVSVVKVGHRQVVSLIRQGGSRLLMKVVSVSR 693
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Ensembl Cavefish
Match: shank3b (SH3 and multiple ankyrin repeat domains protein 3-like [Source:NCBI gene;Acc:103038576]) HSP 1 Score: 323.939 bits (829), Expect = 1.519e-91 Identity = 170/364 (46.70%), Postives = 234/364 (64.29%), Query Frame = 1
Query: 208 FEIKVPDLNLKKSVSLILTETVGMLKKSLIGTLSNDLKDAMNYGLFIPPTEGKAGKFLQEERPLNDYGLHKVHQI--VELRYKRRLYRCTNLNINKLKKLHSKTNLKLFMEHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYYKNEDVVCIRGSPKYNDKRRPSVATSTFLHRSRSAS 1293
I +PDL K + L L V + K+ ++ TL+ L D +NYGL++P G+AGKFL EER L +Y L V + +E RYKRR+Y ++++ +L KLH+K NLK FME+V ++ KV + L KG+DPNF ++GE+PL A L +LIK+L GGAHLD+R +G T LH A N A+ LLDLG SP+ D GLTPLYHS + C E LL+D++ +G DENG QEIHQACR G HLE+LL Y A++++Q + +GNT LH+CA NQ+SCAR+LLFRGA++ +KN +A+Q AI++ N ++A +I+ +K DVV R SP Y+ +RR V S RSAS
Sbjct: 57 IRIGIPDLQQTKCLRLDLEAPVWVCKQRVLVTLTQSLTDVLNYGLYLPAFNGRAGKFLDEERLLREYPLPTVTPVPYLEFRYKRRVYTQSHVDDKQLAKLHTKANLKKFMEYVQQRNVEKVCRFLEKGLDPNFHDTDSGESPLTLAAQLDSSADLIKILRSGGAHLDFRTRDGITALHKAVQTHNDVALTTLLDLGASPDYKDSRGLTPLYHSAMVGGDPYCCELLLYDHAQLGYSDENGWQEIHQACRHGNVQHLEHLLFYGAEMSAQNA-SGNTALHLCALYNQDSCARVLLFRGANKEIKNYNNQTAFQVAIIAGNFDLAEIIKIHKTSDVVPFRESPSYSSRRR-GVCVSPRRSLMRSAS 418 HSP 2 Score: 98.5969 bits (244), Expect = 2.848e-20 Identity = 49/95 (51.58%), Postives = 64/95 (67.37%), Query Frame = 1
Query: 1783 VVLQK-NSQGFGFVIRGLKASSTIN-FRPTLKNPALQYFEEVEVNSVAARAGLKKGDFILEINNLSVVSASHEDTVRLIKASGDILAMKVVTVNK 2061
LQK +S+GFGFV+RG KA + I F PT PALQY E V++ VA RAGL+ GDF++E+N +SVV H V LI+ G L MKVV+V++
Sbjct: 599 ATLQKRDSEGFGFVLRGAKAETPIEEFTPTPAFPALQYLESVDLEGVAWRAGLRTGDFLIEVNGVSVVKVGHRQVVSLIRQGGSRLLMKVVSVSR 693
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Ensembl Cavefish
Match: shank2b (SH3 and multiple ankyrin repeat domains 2b [Source:ZFIN;Acc:ZDB-GENE-061207-58]) HSP 1 Score: 305.449 bits (781), Expect = 2.456e-85 Identity = 151/331 (45.62%), Postives = 215/331 (64.95%), Query Frame = 1
Query: 238 KKSVSLILTETVGMLKKSLIGTLSNDLKDAMNYGLFIPPTEGKAGKFLQEERPLNDYGL--HKVHQIVELRYKRRLYRCTNLNINKLKKLHSKTNLKLFMEHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYYKNEDVVCIRGSP 1224
+KS+ TV K+ ++ TL+ L+D +NYGLF P +G+ FL+EERPL DY L +K +E RYK R+Y+ N+N +++KLH++ NL+ FMEH+ + + KVSK+L +G+DPN+ +TGETPL A L VE+I VL GAHLD+R +G TPLH A N A+K +L+LG SP+ D++GLTPLYH++ +C E LL ++ + DENG E+HQACR+G HLE+LL Y AD+ Q + +GNT LHICA QE+CAR+LL RGA + VKN G + +Q AI++ N +A I+ +K+ D+V R +P
Sbjct: 47 QKSMRFKPDATVWAAKQQILCTLTQSLRDVLNYGLFQPAVDGRESCFLEEERPLRDYSLPTNKGVPTLEFRYKSRVYQHANVNEKQIEKLHTQANLRKFMEHIQHHQVDKVSKLLERGLDPNYHDPDTGETPLTLAAHLDNVVEIITVLKNRGAHLDFRSRDGMTPLHKAVRAKNQIALKAMLELGASPDYKDRQGLTPLYHTVTVGGDPSCCEVLLRAHATVACHDENGWHEVHQACRYGHVQHLEHLLFYGADMRVQNA-SGNTALHICALYKQENCARVLLVRGASKDVKNHRGQTPFQVAIIAGNFELAEFIKNHKDTDIVPFREAP 376 HSP 2 Score: 92.4337 bits (228), Expect = 1.856e-18 Identity = 45/96 (46.88%), Postives = 67/96 (69.79%), Query Frame = 1
Query: 1780 VVVLQKNSQGFGFVIRGLKASSTIN-FRPTLKNPALQYFEEVEVNSVAARAGLKKGDFILEINNLSVVSASHEDTVRLIKASGDILAMKVVTVNKD 2064
VV+ +K+++GFGFV+RG KA + I F PT PALQY E V+ VA +AGL+ GDF++E+N +VV H+ V +I+ G+ L +KVVTV+++
Sbjct: 605 VVLQKKDNEGFGFVLRGAKADTPIEEFTPTPAFPALQYLESVDEGGVAWQAGLRTGDFLIEVNQDNVVKVGHKQVVNMIRHGGNHLIIKVVTVSRN 700
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Ensembl Cavefish
Match: shank2a (SH3 and multiple ankyrin repeat domains 2a [Source:ZFIN;Acc:ZDB-GENE-120215-55]) HSP 1 Score: 302.753 bits (774), Expect = 2.397e-84 Identity = 167/373 (44.77%), Postives = 232/373 (62.20%), Query Frame = 1
Query: 187 NNNQCFKFEIKVPDLNLKKSVSLILTETVGMLKKSLIGTLSNDLKDAMNYGLFIPPTEGKAGKFLQEERPLNDY--GLHKVHQIVELRYKRRLYRCTNLNINKLKKLHSKTNLKLFMEHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYYKNEDVVCIRGSPKYNDKRRP----SVATSTFLHRSRS 1287
N +C +F PD TV + K+ ++ TLS LKD +NYGLF P + G+ GKFL EER L +Y + K +E RYK R+Y+ N++ ++ KLH+K NL+ FM+++ N + KVSKML++G+DPN+Q +TGETPL A L VE+IKVL GGAHLD+R +G T LH AA N + LL+LG SP+ D GLT LYH+ + AC E LL +++ + +DENG E+HQACR G HLE+LL Y AD+++Q + +GNT LHICA NQ++CAR+LL RGAD+ VKN S +Q AI++ N +A LI+ ++ D+V R +P Y+ +RR S+A L RS S
Sbjct: 69 NTTKCMRFN---PDA------------TVWVAKQRILCTLSQSLKDVLNYGLFQPASNGRDGKFLDEERLLREYPQSISKGVPSLEFRYKSRVYKQPNVDEKQIAKLHTKANLRKFMDYIQNQQVEKVSKMLDRGLDPNYQDPDTGETPLTFAAHLENGVEMIKVLKNGGAHLDFRAKDGMTALHKAARSKNSTTLTTLLELGASPDYKDSRGLTALYHTAMVGGDPACCELLLHEHASVCCQDENGWHEVHQACRHGHVQHLEHLLFYGADMSAQNA-SGNTALHICALYNQDNCARVLLIRGADKEVKNYNSQSPFQVAIIAGNFELAELIKNHRESDIVPFREAPAYSQRRRGPQPNSLAAPRTLLRSNS 425 HSP 2 Score: 90.5077 bits (223), Expect = 8.348e-18 Identity = 47/104 (45.19%), Postives = 65/104 (62.50%), Query Frame = 1
Query: 1759 DTSFLPRVVVLQK-NSQGFGFVIRGLKASSTIN-FRPTLKNPALQYFEEVEVNSVAARAGLKKGDFILEINNLSVVSASHEDTVRLIKASGDILAMKVVTVNKD 2064
D + + V LQK +GFGFV+RG KA + I F PT PALQY E V+ VA +AGL+ GDF++E+N +VV H V +I+ G+ L +KVVTV ++
Sbjct: 618 DCALEQKTVELQKKQEEGFGFVLRGAKADTPIEEFTPTPAFPALQYLESVDEGGVAWQAGLRTGDFLIEVNQENVVKVGHRQVVNMIRQGGNRLIIKVVTVTRN 721
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Ensembl Cavefish
Match: shank1 (SH3 and multiple ankyrin repeat domains 1 [Source:ZFIN;Acc:ZDB-GENE-130530-691]) HSP 1 Score: 301.597 bits (771), Expect = 5.616e-84 Identity = 157/373 (42.09%), Postives = 227/373 (60.86%), Query Frame = 1
Query: 169 SSVATNNNNQCFKFEIKVPDLNLKKSVSLILTETVGMLKKSLIGTLSNDLKDAMNYGLFIPPTEGKAGKFLQEERPLNDY--GLHKVHQIVELRYKRRLYRCTNLNINKLKKLHSKTNLKLFMEHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPV--ELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYYKNEDVVCIRGSPKYNDKRRPSVATSTFLH 1275
SS + + F I +PD+ K + TV K+ ++ +L+ L+D +NYGLF P T+G KFL+EERPL DY K +E RYK R+Y+ TNL+ +L KLH+K +LK FM+++ + KV+K L+KG+DPN+ +TG P + +P E+I+VLV GGAH+D+R +G T LH A A LL LG SP+ D+ GLTPLYH++++ +C E LL+ + +G+ DENG E HQAC+ G + HLE+LL Y AD SQ + +GNT LHICA N+ESCAR+LL+RGA + KN +G + +Q A++S + + +I+ +++ DVV SPKY +RR S T H
Sbjct: 51 SSAPDDTHIAMMVFRIGIPDIKQTKCLRFNPEATVWKAKQQVLCSLTESLRDVLNYGLFQPATDGHDAKFLEEERPLRDYPQSFEKGVPYLEFRYKTRVYKQTNLDEKQLAKLHTKASLKKFMDYIQTGSVEKVAKFLDKGLDPNYHDPDTGGEPPLTLAVQCEPGAGEVIRVLVMGGAHIDFRAKDGLTSLHKAV---RAHAHTTLLSLGASPDYKDRRGLTPLYHTVLTGGDTSCCETLLYHRAKLGLRDENGWDETHQACQNGNSQHLEHLLFYGADSTSQNA-SGNTALHICALYNKESCARILLYRGAKKDTKNNSGQTPFQVAVMSGHFELGEIIKNHRDSDVVPFLESPKYAPQRRESGRTLALPH 419 HSP 2 Score: 94.3597 bits (233), Expect = 5.351e-19 Identity = 49/105 (46.67%), Postives = 67/105 (63.81%), Query Frame = 1
Query: 1780 VVVLQKNSQGFGFVIRGLKASSTIN-FRPTLKNPALQYFEEVEVNSVAARAGLKKGDFILEINNLSVVSASHEDTVRLIKASGDILAMKVVTV--NKDKLDEQRK 2085
V++ +K+S+GFGFV+RG KA + I F PT PALQY E V+ VA RAGL+ GDF++E+N +VV H V +I+ G+ L +KVV V N D + RK
Sbjct: 624 VLLQKKDSEGFGFVLRGAKAQTPIEEFTPTPAFPALQYLESVDEGGVAWRAGLRMGDFLIEVNGQNVVKVGHRQVVNMIRQGGNSLMVKVVMVTRNPDMEEGSRK 728
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007446.1 (pep scaffold:Pmarinus_7.0:GL478728:200023:240674:1 gene:ENSPMAG00000006704.1 transcript:ENSPMAT00000007446.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 89.3521 bits (220), Expect = 3.353e-18 Identity = 72/244 (29.51%), Postives = 116/244 (47.54%), Query Frame = 1
Query: 472 NLNINKLKKLHSKTNLKLFMEHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIA-MLIQYYKNED 1200
++ ++ L LH H G+ KV +L+KG +PN + G TPL AC + + ++++L++ GA ++ +G TP+H +A +GNL V ILL G SPN + G T L H LL + + + + +H A R G+ ++ LLQ+ A ++ TS NG TPLH+ A E +LL GA V + G + A +A +L+Q + + D
Sbjct: 67 DITLDYLTALH-------VAAHCGHYRTAKV--LLDKGANPNVRAL-NGFTPLHIACKKNR-IRVMELLLKYGASIEAVTESGLTPMHVSAFMGNLNIVLILLQGGASPNATNVRGETAL-HMAARAGQTEVVRSLLRNGAQVDAKAREEQTPLHIAARLGKLEIVQLLLQHMASPDAATS-NGYTPLHVAAREGHEDVTAILLEHGASLAVTTKKGFTPLHVASKYGKMEVASLLLQRFASPD 297 HSP 2 Score: 88.1965 bits (217), Expect = 8.454e-18 Identity = 70/220 (31.82%), Postives = 103/220 (46.82%), Query Frame = 1
Query: 538 VGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYYKNE 1197
+GN +I V +L G PN GET L A Q E+++ L+ GA +D + TPLH AA LG LE V++LL SP+ G TPL H + T LL + + + + G +H A ++G+ LLQ A ++ KNG TPLH+ ++ + + A LLL +GA + G++ A D IA + Y E
Sbjct: 148 MGNLNI--VLILLQGGASPN-ATNVRGETALHMAARAGQ-TEVVRSLLRNGAQVDAKAREEQTPLHIAARLGKLEIVQLLLQHMASPDAATSNGYTPL-HVAAREGHEDVTAILLEHGASLAVTTKKGFTPLHVASKYGKMEVASLLLQRFASPDA-AGKNGLTPLHVASHYDNQKVALLLLDQGASPHATAKNGYTPLHIAAKKDQLEIATTLLEYGAE 361 HSP 3 Score: 69.3218 bits (168), Expect = 3.984e-12 Identity = 67/229 (29.26%), Postives = 106/229 (46.29%), Query Frame = 1
Query: 565 SKMLNKGIDPNFQIKETGETPLIKACSL-TQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIA-MLIQYYKNEDVVCIRGSPKYNDKRR 1245
S +L + P+ K G TPL A Q V L+ L++ GA NG+TPLH AA LE LL+ G N I ++G+ PL H + A LL Y+ + ++GL +H A + + + E L+++ A +N+ T+K G TPL + + LL GAD K + G++ QA + +I +L++ + V + G+ RR
Sbjct: 287 SLLLQRFASPDAAGK-NGLTPLHVASHYDNQKVALL--LLDQGASPHATAKNGYTPLHIAAKKDQLEIATTLLEYGAETNAITRQGVAPL-HLGAQEGHADVASLLLARYADVNHATKSGLSPLHLAAQEDKVNVAEILVKHGAHVNA-TTKLGYTPLIVACHYGNIKMVNFLLQHGADVNSKTKNGYTPLHQAAQQGHTHIVNLLLKCGARPNDVTVNGNTALAIARR 510 HSP 4 Score: 66.2402 bits (160), Expect = 3.921e-11 Identity = 49/166 (29.52%), Postives = 83/166 (50.00%), Query Frame = 1
Query: 661 ELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAAC----TERLLFDYSI-IGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQA 1143
+++++L+E GA + + NG +PLH A ++E V++L+ + I + LT L+ AA C T ++L D + NG +H AC+ R +E LL+Y A I + T ++G TP+H+ A++ + +LL GA N G +A A
Sbjct: 20 QVVEILLEQGAPILAKTKNGLSPLHMATQGDHVECVQVLMQYRAPVDDITLDYLTALH------VAAHCGHYRTAKVLLDKGANPNVRALNGFTPLHIACKKNRIRVMELLLKYGASIEAVT-ESGLTPMHVSAFMGNLNIVLILLQGGASPNATNVRGETALHMA 178 HSP 5 Score: 61.2326 bits (147), Expect = 1.230e-9 Identity = 56/188 (29.79%), Postives = 85/188 (45.21%), Query Frame = 1
Query: 658 VELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAI-LSDNKNIAMLIQYYKNEDVVCIRG 1218
VE ++VL++ A +D + T LH AA G+ K+LLD G +PN G TPL+ + + L + SI + E+GL +H + G + + LLQ A N+ T+ G T LH+ A Q R LL GA K R + A L + + +L+Q+ + D G
Sbjct: 52 VECVQVLMQYRAPVDDITLDYLTALHVAAHCGHYRTAKVLLDKGANPNVRALNGFTPLHIACKKNRIRVMELLLKYGASIEAV-TESGLTPMHVSAFMGNLNIVLILLQGGASPNA-TNVRGETALHMAARAGQTEVVRSLLRNGAQVDAKAREEQTPLHIAARLGKLEIVQLLLQHMASPDAATSNG 237
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007449.1 (pep scaffold:Pmarinus_7.0:GL478728:201453:233342:1 gene:ENSPMAG00000006704.1 transcript:ENSPMAT00000007449.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 88.1965 bits (217), Expect = 6.512e-18 Identity = 70/220 (31.82%), Postives = 103/220 (46.82%), Query Frame = 1
Query: 538 VGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYYKNE 1197
+GN +I V +L G PN GET L A Q E+++ L+ GA +D + TPLH AA LG LE V++LL SP+ G TPL H + T LL + + + + G +H A ++G+ LLQ A ++ KNG TPLH+ ++ + + A LLL +GA + G++ A D IA + Y E
Sbjct: 58 MGNLNI--VLILLQGGASPN-ATNVRGETALHMAARAGQ-TEVVRSLLRNGAQVDAKAREEQTPLHIAARLGKLEIVQLLLQHMASPDAATSNGYTPL-HVAAREGHEDVTAILLEHGASLAVTTKKGFTPLHVASKYGKMEVASLLLQRFASPDA-AGKNGLTPLHVASHYDNQKVALLLLDQGASPHATAKNGYTPLHIAAKKDQLEIATTLLEYGAE 271 HSP 2 Score: 87.4261 bits (215), Expect = 1.085e-17 Identity = 65/211 (30.81%), Postives = 104/211 (49.29%), Query Frame = 1
Query: 571 MLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIA-MLIQYYKNED 1200
+L+KG +PN + G TPL AC + + ++++L++ GA ++ +G TP+H +A +GNL V ILL G SPN + G T L H LL + + + + +H A R G+ ++ LLQ+ A ++ TS NG TPLH+ A E +LL GA V + G + A +A +L+Q + + D
Sbjct: 1 LLDKGANPNVR-ALNGFTPLHIACKKNR-IRVMELLLKYGASIEAVTESGLTPMHVSAFMGNLNIVLILLQGGASPNATNVRGETAL-HMAARAGQTEVVRSLLRNGAQVDAKAREEQTPLHIAARLGKLEIVQLLLQHMASPDAATS-NGYTPLHVAAREGHEDVTAILLEHGASLAVTTKKGFTPLHVASKYGKMEVASLLLQRFASPD 207 HSP 3 Score: 69.707 bits (169), Expect = 2.949e-12 Identity = 67/229 (29.26%), Postives = 106/229 (46.29%), Query Frame = 1
Query: 565 SKMLNKGIDPNFQIKETGETPLIKACSL-TQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIA-MLIQYYKNEDVVCIRGSPKYNDKRR 1245
S +L + P+ K G TPL A Q V L+ L++ GA NG+TPLH AA LE LL+ G N I ++G+ PL H + A LL Y+ + ++GL +H A + + + E L+++ A +N+ T+K G TPL + + LL GAD K + G++ QA + +I +L++ + V + G+ RR
Sbjct: 197 SLLLQRFASPDAAGKN-GLTPLHVASHYDNQKVALL--LLDQGASPHATAKNGYTPLHIAAKKDQLEIATTLLEYGAETNAITRQGVAPL-HLGAQEGHADVASLLLARYADVNHATKSGLSPLHLAAQEDKVNVAEILVKHGAHVNA-TTKLGYTPLIVACHYGNIKMVNFLLQHGADVNSKTKNGYTPLHQAAQQGHTHIVNLLLKCGARPNDVTVNGNTALAIARR 420
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000093.1 (pep scaffold:Pmarinus_7.0:GL477582:20502:66045:1 gene:ENSPMAG00000000080.1 transcript:ENSPMAT00000000093.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 80.1073 bits (196), Expect = 1.928e-15 Identity = 67/209 (32.06%), Postives = 98/209 (46.89%), Query Frame = 1
Query: 499 LHSKTNLKLFMEHVGN--ADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGAD--RTVKN 1113
+H+ T L HV + + V +L G N GETPL A Q +E++K L++ GA + + TPLH A+ LG E V++LL G PN G TPLY + + LL + + I + G +H A ++GR LL+ A + + KNG TPLH+ + + + A LLL +GA T KN
Sbjct: 403 IHTTTESGLTPIHVASFMGHLNVVQLLLQNGASSN-ATNVRGETPLHMASRAGQ-LEVVKTLLQSGARVGVKAREDQTPLHIASRLGKAEIVQLLLQRGSDPNAPTASGSTPLYFA-SREGHGDVASLLLENGADISPVTKKGFTPLHIASKYGRLEVATLLLEKYASADPK-GKNGLTPLHVATHYDHQKVALLLLDKGASPHSTAKN 607 HSP 2 Score: 79.337 bits (194), Expect = 3.471e-15 Identity = 64/223 (28.70%), Postives = 114/223 (51.12%), Query Frame = 1
Query: 535 HVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIA-MLIQYYKNED 1200
H G+ + K+ +L++G +PN + G TPL AC + ++++++L++ GA + +G TP+H A+ +G+L V++LL G S N + G TPL H + LL + +G++ +H A R G+ ++ LLQ +D N+ T+ +G+TPL+ + A LLL GAD + + G + A +A +L++ Y + D
Sbjct: 353 HCGHYRVAKL--LLDRGGEPNARALN-GFTPLHIACKKNR-IKVMELLLKHGASIHTTTESGLTPIHVASFMGHLNVVQLLLQNGASSNATNVRGETPL-HMASRAGQLEVVKTLLQSGARVGVKAREDQTPLHIASRLGKAEIVQLLLQRGSDPNAPTA-SGSTPLYFASREGHGDVASLLLENGADISPVTKKGFTPLHIASKYGRLEVATLLLEKYASAD 569 HSP 3 Score: 77.411 bits (189), Expect = 1.323e-14 Identity = 66/192 (34.38%), Postives = 96/192 (50.00%), Query Frame = 1
Query: 523 LFMEHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGAD 1098
L ++H NAD+ SKM+ Q E+G TPL A + + +L+ GA +D+ NG TPLH AA GN VK+LLD G +T ++GLTPL H E LL + I + +NGL +H A + ++ LL +A ++ T + TPLH+ A+ A+LLL RG +
Sbjct: 189 LLLQHEHNADV--TSKMMLN------QTTESGFTPLHIAAHYGN-MNVATLLLNLGAAVDFTARNGITPLHVAAKRGNNNMVKLLLDRGAKIDTKTRDGLTPL-HCAARSGHEKVIEMLLERDAPILAKTKNGLSPLHMATQGEHLACVQLLLGRQAPVDDVT-LDYLTPLHVAAHCGHYRVAKLLLDRGGE 369 HSP 4 Score: 75.485 bits (184), Expect = 4.512e-14 Identity = 64/212 (30.19%), Postives = 102/212 (48.11%), Query Frame = 1
Query: 616 GETPLIKACSLT-QPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIA-MLIQYYKNEDVVCIRGSPKYNDKRR 1245
G TPL A Q V L+ L++ GA NG+TPLH AA LE K+LL+LG N + Q+G+ PL H + A LL ++ I + + GL +H A + + + E L +++AD+N+ T+K TPLH+ ++ LL A K R G++ QA + ++ L+Q+ + + + G+ RR
Sbjct: 575 GLTPLHVATHYDHQKVALL--LLDKGASPHSTAKNGYTPLHIAAKKNQLEVGKVLLELGAETNMLTQQGVAPL-HLAAQEGHADMVALLLGRHASISLATKGGLTAMHLAAQEDKVNVAEILTKHKADVNT-TTKLCYTPLHVASHYGNIKMVNFLLRNRALVNAKTRNGYTPLHQAAQQGHTHVVNALLQHEASPNELTANGNTALAIARR 782 HSP 5 Score: 72.7886 bits (177), Expect = 3.697e-13 Identity = 69/220 (31.36%), Postives = 108/220 (49.09%), Query Frame = 1
Query: 541 GNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYR--ADINS-----QTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLI 1179
G+ D+ V+++L + + + K G T L +L ++++VLVE GA+++ + NG TPL+ AA +LE VK LLD G + + ++G TPL ++ LL + G + L +H A R T+ LLQ+ AD+ S QT+++G TPLHI A+ + A LLL GA R G + A N N+ L+
Sbjct: 54 GHVDV--VTELLKREAEIDTATK-VGNTAL-HIAALAGQTDIVRVLVEFGANINAQSQNGFTPLYMAAQENHLEIVKFLLDNGANQSVATEDGFTPL--AVALQQGHEQVVGLLLESDTKG---KVRLPALHIAARKDDTNAAALLLQHEHNADVTSKMMLNQTTESGFTPLHIAAHYGNMNVATLLLNLGAAVDFTARNGITPLHVAAKRGNNNMVKLL 264 HSP 6 Score: 65.855 bits (159), Expect = 4.127e-11 Identity = 76/258 (29.46%), Postives = 112/258 (43.41%), Query Frame = 1
Query: 559 KVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAI-LSDNKNIAMLIQYYKNEDVVCIRGS-PKYNDKRRPSVATSTFLHRSRSASRIMDISQVDKR 1326
KV +ML + P + G +PL A + + +++L+ A +D + TPLH AA G+ K+LLD G PN G TPL H E LL + I E+GL IH A G + ++ LLQ A N+ T+ G TPLH+ + Q + LL GA VK R + A L + + +L+Q + + GS P Y R ++ L + + DIS V K+
Sbjct: 292 KVIEMLLERDAPILAKTKNGLSPLHMATQ-GEHLACVQLLLGRQAPVDDVTLDYLTPLHVAAHCGHYRVAKLLLDRGGEPNARALNGFTPL-HIACKKNRIKVMELLLKHGASIHTTTESGLTPIHVASFMGHLNVVQLLLQNGASSNA-TNVRGETPLHMASRAGQLEVVKTLLQSGARVGVKAREDQTPLHIASRLGKAEIVQLLLQRGSDPNAPTASGSTPLYFASREGHGDVASLLLENGA-----DISPVTKK 541
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000095.1 (pep scaffold:Pmarinus_7.0:GL477582:20897:60453:1 gene:ENSPMAG00000000080.1 transcript:ENSPMAT00000000095.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 78.9518 bits (193), Expect = 3.850e-15 Identity = 64/223 (28.70%), Postives = 114/223 (51.12%), Query Frame = 1
Query: 535 HVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIA-MLIQYYKNED 1200
H G+ + K+ +L++G +PN + G TPL AC + ++++++L++ GA + +G TP+H A+ +G+L V++LL G S N + G TPL H + LL + +G++ +H A R G+ ++ LLQ +D N+ T+ +G+TPL+ + A LLL GAD + + G + A +A +L++ Y + D
Sbjct: 346 HCGHYRVAKL--LLDRGGEPNARALN-GFTPLHIACKKNR-IKVMELLLKHGASIHTTTESGLTPIHVASFMGHLNVVQLLLQNGASSNATNVRGETPL-HMASRAGQLEVVKTLLQSGARVGVKAREDQTPLHIASRLGKAEIVQLLLQRGSDPNAPTA-SGSTPLYFASREGHGDVASLLLENGADISPVTKKGFTPLHIASKYGRLEVATLLLEKYASAD 562 HSP 2 Score: 78.9518 bits (193), Expect = 3.983e-15 Identity = 66/210 (31.43%), Postives = 99/210 (47.14%), Query Frame = 1
Query: 499 LHSKTNLKLFMEHVGN--ADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTS-KNGNTPLHICAYLNQESCARLLLFRGAD--RTVKN 1113
+H+ T L HV + + V +L G N GETPL A Q +E++K L++ GA + + TPLH A+ LG E V++LL G PN G TPLY + + LL + + I + G +H A ++GR LL+ A + + + +NG TPLH+ + + + A LLL +GA T KN
Sbjct: 396 IHTTTESGLTPIHVASFMGHLNVVQLLLQNGASSN-ATNVRGETPLHMASRAGQ-LEVVKTLLQSGARVGVKAREDQTPLHIASRLGKAEIVQLLLQRGSDPNAPTASGSTPLYFA-SREGHGDVASLLLENGADISPVTKKGFTPLHIASKYGRLEVATLLLEKYASADPKVAGQNGLTPLHVATHYDHQKVALLLLDKGASPHSTAKN 602 HSP 3 Score: 76.2554 bits (186), Expect = 3.061e-14 Identity = 66/221 (29.86%), Postives = 105/221 (47.51%), Query Frame = 1
Query: 589 DPNFQIKETGETPLIKACSLT-QPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIA-MLIQYYKNEDVVCIRGSPKYNDKRR 1245
DP + G TPL A Q V L+ L++ GA NG+TPLH AA LE K+LL+LG N + Q+G+ PL H + A LL ++ I + + GL +H A + + + E L +++AD+N+ T+K TPLH+ ++ LL A K R G++ QA + ++ L+Q+ + + + G+ RR
Sbjct: 562 DPKVA-GQNGLTPLHVATHYDHQKVALL--LLDKGASPHSTAKNGYTPLHIAAKKNQLEVGKVLLELGAETNMLTQQGVAPL-HLAAQEGHADMVALLLGRHASISLATKGGLTAMHLAAQEDKVNVAEILTKHKADVNT-TTKLCYTPLHVASHYGNIKMVNFLLRNRALVNAKTRNGYTPLHQAAQQGHTHVVNALLQHEASPNELTANGNTALAIARR 777 HSP 4 Score: 72.0182 bits (175), Expect = 5.372e-13 Identity = 71/221 (32.13%), Postives = 108/221 (48.87%), Query Frame = 1
Query: 541 GNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGI---EDENG---LQEIHQACRFGRTHHLEYLLQYR--ADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLI 1179
G+ D+ V+++L + + + K G T L +L ++++VLVE GA+++ + NG TPL+ AA +LE VK LLD G + + ++G TPL A A + ++G+ D G L +H A R T+ LLQ+ AD+ TSK+G TPLHI A+ + A LLL GA R G + A N N+ L+
Sbjct: 55 GHVDV--VTELLKREAEIDTATK-VGNTAL-HIAALAGQTDIVRVLVEFGANINAQSQNGFTPLYMAAQENHLEIVKFLLDNGANQSVATEDGFTPL--------AVALQQG---HEQVVGLLLESDTKGKVRLPALHIAARKDDTNAAALLLQHEHNADV---TSKSGFTPLHIAAHYGNMNVATLLLNLGAAVDFTARNGITPLHVAAKRGNNNMVKLL 257 HSP 5 Score: 69.707 bits (169), Expect = 2.855e-12 Identity = 61/192 (31.77%), Postives = 91/192 (47.40%), Query Frame = 1
Query: 523 LFMEHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGAD 1098
L ++H NAD+ ++G TPL A + + +L+ GA +D+ NG TPLH AA GN VK+LLD G +T ++GLTPL H E LL + I + +NGL +H A + ++ LL +A ++ T + TPLH+ A+ A+LLL RG +
Sbjct: 190 LLLQHEHNADV----------------TSKSGFTPLHIAAHYGN-MNVATLLLNLGAAVDFTARNGITPLHVAAKRGNNNMVKLLLDRGAKIDTKTRDGLTPL-HCAARSGHEKVIEMLLERDAPILAKTKNGLSPLHMATQGEHLACVQLLLGRQAPVDDVT-LDYLTPLHVAAHCGHYRVAKLLLDRGGE 362 HSP 6 Score: 65.855 bits (159), Expect = 3.870e-11 Identity = 76/258 (29.46%), Postives = 112/258 (43.41%), Query Frame = 1
Query: 559 KVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAI-LSDNKNIAMLIQYYKNEDVVCIRGS-PKYNDKRRPSVATSTFLHRSRSASRIMDISQVDKR 1326
KV +ML + P + G +PL A + + +++L+ A +D + TPLH AA G+ K+LLD G PN G TPL H E LL + I E+GL IH A G + ++ LLQ A N+ T+ G TPLH+ + Q + LL GA VK R + A L + + +L+Q + + GS P Y R ++ L + + DIS V K+
Sbjct: 285 KVIEMLLERDAPILAKTKNGLSPLHMATQ-GEHLACVQLLLGRQAPVDDVTLDYLTPLHVAAHCGHYRVAKLLLDRGGEPNARALNGFTPL-HIACKKNRIKVMELLLKHGASIHTTTESGLTPIHVASFMGHLNVVQLLLQNGASSNA-TNVRGETPLHMASRAGQLEVVKTLLQSGARVGVKAREDQTPLHIASRLGKAEIVQLLLQRGSDPNAPTASGSTPLYFASREGHGDVASLLLENGA-----DISPVTKK 534
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003991.1 (pep scaffold:Pmarinus_7.0:GL484476:255315:281660:1 gene:ENSPMAG00000003623.1 transcript:ENSPMAT00000003991.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 77.7962 bits (190), Expect = 9.450e-15 Identity = 61/209 (29.19%), Postives = 105/209 (50.24%), Query Frame = 1
Query: 526 FMEHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILS 1152
+ ++G+ ++ KV ++ G D + K+ G +PL A S Q + ++K+L++ G +D +S G+T LH A G V L+D G + N ++ G TPL+ + S A C E L+ + + + ++ ++G +H GR + L+Q +I+ + ++GNTPLHI A E L+ GAD + G A LS
Sbjct: 177 WAAYMGHTEVVKV--LVAHGADVRCKDKK-GYSPLHAASSSGQ-IGVVKLLLDLGVDIDDPNSFGNTALHVACYNGQDVVVNELIDCGANVNQANERGFTPLHFAAASTHGALCLELLVNNGADVNVQSKDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCE-DRDGNTPLHIAARYGHELLINTLITNGADTAKRGIHGMFPLHLAALS 380 HSP 2 Score: 59.3066 bits (142), Expect = 5.096e-9 Identity = 54/219 (24.66%), Postives = 90/219 (41.10%), Query Frame = 1
Query: 619 ETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAA--------------------------------CTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLI 1179
+ PLI+A P E ++ L+ ++ TPLHAAA LG E +++L+ G N+ D + LTPL+ + S AA C E ++ S + D G +H A G + + +L+ A+IN+ K+ +H AY+ ++L+ GAD K++ G+S A S + L+
Sbjct: 7 QAPLIQAIFNGDPDE-VRSLIYKKEEVNAVDDEKRTPLHAAAYLGEAEIIELLVLSGARVNSKDNKWLTPLHRACASRSEAAVQTLLKHSADVNARDKNWQTPLHVAAANRAVKCAEAIIPMLSSSNVSDRAGRTALHHAAFNGHSEMVNFLVAKGANINAFDKKD-RRAIHWAAYMGHTEVVKVLVAHGADVRCKDKKGYSPLHAASSSGQIGVVKLL 223 HSP 3 Score: 57.7658 bits (138), Expect = 1.628e-8 Identity = 52/177 (29.38%), Postives = 79/177 (44.63%), Query Frame = 1
Query: 667 IKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYS----IIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNI-AMLIQ 1182
++VL+ LD R NG+TPL AA+ G+ + V++L+ G S + HS ++ C RLL + + + D N + A G T LL A IN++ +K G T LH A E C LLL R D +++ R G + A + I + L+Q
Sbjct: 599 LEVLIRSLVDLDVREGNGYTPLGLAALRGHTDCVRVLIQHGASVLLKEGPDRRTALHSAATNGHVECL-RLLVENADSNEAVDASDANEQTPVMLAVGNGHTDCASLLLSKGASINAKDNK-GCTALHRGAATGHEECVDLLLQRSVDVSLRERRGRAPLHMAAACGHMGILSALVQ 773 HSP 4 Score: 53.5286 bits (127), Expect = 2.538e-7 Identity = 61/233 (26.18%), Postives = 97/233 (41.63%), Query Frame = 1
Query: 586 IDPNFQIK---ETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISD---------------------------PAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGN--TPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKN-IAMLIQY 1185
+ F+I E G T L A S VE + +L+ GA ++ + T LH AA N++ V L+ G N D+ TPL+++ +D A C E LL + GI+D+ G +H A +G LE LL+ S K+G+ +PLH+ AY +L+ D V+ G++ A L + + + +LIQ+
Sbjct: 408 LSAGFEIDTPDEFGRTCLHAAASGGN-VECLNLLLSTGADMNKKDRFERTALHYAAANCNVQCVVTLVASGARLNEQDERRCTPLHYAAAADGDGSTVSFSVYNTISVQSYIDVHSTCSEAQICLEHLLRKDADPGIQDKQGYTPVHYAAAYGHRVCLELLLEQPGAFQSD-GKSGHPISPLHLAAYHGHHGALEVLIRSLVDLDVREGNGYTPLGLAALRGHTDCVRVLIQH 638 HSP 5 Score: 53.1434 bits (126), Expect = 3.813e-7 Identity = 58/215 (26.98%), Postives = 98/215 (45.58%), Query Frame = 1
Query: 466 CTNLNINKLKKLHSKTNLKLFMEHVGNADIGK--VSKMLNKGIDPNFQIKETGETPL--IKACS-LTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEG--LTPLYHSIISDPAAACTERLL--FDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLL 1083
C +L ++K +++K N H G A + V +L + +D + + + G PL AC + L++ + GA + NG+TPLH A G+ V++LL+L QEG +PL+ ++++D +C E L+ F II D G +H A L+ LL + A +N T G +PL + Q + +L+
Sbjct: 701 CASLLLSKGASINAKDNKGCTALHRGAATGHEECVDLLLQRSVDVSLR-ERRGRAPLHMAAACGHMGILSALVQAAMASGAPIPLTDRNGYTPLHWACYNGHDGCVELLLELDVFQK---QEGNAFSPLHCAVLND-NESCAEMLIDTFGAKIINCPDAKGRMPLHAAAFTDHVECLQLLLSHNALVNV-TDMAGKSPLMMACENGQATAVEVLV 909 HSP 6 Score: 51.2174 bits (121), Expect = 1.652e-6 Identity = 58/271 (21.40%), Postives = 108/271 (39.85%), Query Frame = 1
Query: 622 TPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKN--------------------------------GNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYYKNEDVVCIRGSPKYNDKRRPSVATSTFLHRSRSASRIMDISQVDKREDSG 1338
TPL +AC+ ++ ++ L++ A ++ R N TPLH AA ++ + ++ + S N D+ G T L+H+ + + L+ + I D+ + IH A G T ++ L+ + AD+ + K GNT LH+ Y Q+ L+ GA+ N G + A S + + + + DV + + D + P T+ +RS + I + ++D + G
Sbjct: 74 TPLHRACA-SRSEAAVQTLLKHSADVNARDKNWQTPLHVAAANRAVKCAEAIIPMLSSSNVSDRAGRTALHHAAFNGHSEM-VNFLVAKGANINAFDKKDRRAIHWAAYMGHTEVVKVLVAHGADVRCKDKKGYSPLHAASSSGQIGVVKLLLDLGVDIDDPNSFGNTALHVACYNGQDVVVNELIDCGANVNQANERGFTPLHFAAASTHGALCLELLVNNGADV-----NVQSKDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCEDRDG 337
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Ensembl Yeast
Match: NAS6 (Evolutionarily conserved 19S regulatory particle assembly-chaperone; proteasome-interacting protein involved in the assembly of the base subcomplex of the 19S proteasomal regulatory particle (RP); ortholog of human oncoprotein gankyrin, also known as p28, which interacts with the Rb tumor suppressor and CDK4/6 [Source:SGD;Acc:S000003464]) HSP 1 Score: 51.9878 bits (123), Expect = 1.289e-7 Identity = 37/126 (29.37%), Postives = 67/126 (53.17%), Query Frame = 1
Query: 538 VGNADIGKVSKMLNKGIDPNF-QIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSP-NTIDQEGLTPLYHSII---SDPAAACTERLLFDYSII 900
VGN ++ V + ++ + P+ +I G T L A + E+ + L+E GA + + PLH AA +G+L+ +++L LG+S N D++G TPL+H++ D A E+ +Y ++
Sbjct: 82 VGNLEV--VKSLYDRPLKPDLNKITNQGVTCLHLAVG-KKWFEVSQFLIENGASVRIKDKFNQIPLHRAASVGSLKLIELLCGLGKSAVNWQDKQGWTPLFHALAEGHGDAAVLLVEKYGAEYDLV 204 HSP 2 Score: 50.0618 bits (118), Expect = 5.380e-7 Identity = 54/202 (26.73%), Postives = 88/202 (43.56%), Query Frame = 1
Query: 559 KVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHL---DYRHSNGHTPLHAAAILGNLEAVKILLDLGQSP--NTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPL-HICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAI 1146
KV ++L+ Q + G PL + S Q E+ L+ ++ DY +G TP H A +GNLE VK L D P N I +G+T L H + ++ L+ + + + I+D+ +H+A G +E L + K G TPL H A + ++ L+ GA+ + + G A A+
Sbjct: 17 KVQELLHSKPSLLLQKDQDGRIPLHWSVSF-QAHEITSFLLSKMENVNLDDYPDDSGWTPFHIACSVGNLEVVKSLYDRPLKPDLNKITNQGVTCL-HLAVGKKWFEVSQFLIENGASVRIKDKFNQIPLHRAASVGSLKLIELLCGLGKSAVNWQDKQGWTPLFHALAEGHGDAAVLLVEKYGAEYDLVDNKGAKAEDVAL 216
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Ensembl Yeast
Match: AKR1 (Palmitoyl transferase involved in protein palmitoylation; acts as a negative regulator of pheromone response pathway; required for endocytosis of pheromone receptors; involved in cell shape control; contains ankyrin repeats; AKR1 has a paralog, AKR2, that arose from the whole genome duplication; any of several human homologs encoding DHHC-type zinc fingers (ZDHHC) can complement temperature sensitivity of yeast akr1 null mutant [Source:SGD;Acc:S000002672]) HSP 1 Score: 49.2914 bits (116), Expect = 3.205e-6 Identity = 53/206 (25.73%), Postives = 83/206 (40.29%), Query Frame = 1
Query: 547 ADIGKVSKMLN-KGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGH-TPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGI-----EDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQA 1143
D+ V +M++ K ++ N T + S+ + ++ LV GA ++ R H TPLH AA G + V LL G P D +G L H ++ +LF+ G+ D G + A G + + LL++ A I ++ G TPLH Q + L+ GAD K G + A
Sbjct: 84 GDLATVKEMIHGKLLEVNNDGDSTEHITGLHWASINNRLSVVDFLVSQGADVNARAGALHATPLHWAARYGYVYIVDFLLKHGADPTMTDDQGFN-LLHLSVNSSNIMLVLYVLFNVVSKGLLDIDCRDPKGRTSLLWAAYQGDSLTVAELLKFGASIKIADTE-GFTPLHWGTVKGQPHVLKYLIQDGADFFQKTDTGKDCFAIA 287
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Ensembl Nematostella
Match: EDO42616 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S0X5]) HSP 1 Score: 290.041 bits (741), Expect = 2.184e-85 Identity = 149/330 (45.15%), Postives = 207/330 (62.73%), Query Frame = 1
Query: 265 ETVGMLKKSLIGTLSNDLKDAMNYGLFIPPTEGKAGKFLQEERPLNDYGLHKVHQIVELRYKRRLYRCTNLNINKLKKLHSKTNLKLFMEHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYYKNEDVVCIRGSPKYNDKRRPSV 1254
E + + K +I L+ +KDA+NYG + PP G++GKFL EER +Y +E +YKRR+Y+ + L+K+H+K NLK ++ V I +V+K+ +KG+DPNFQ +TGETPL A Q ++LI LV GGAHLDYR +G T +H AAI G + ++K LLDLG SPN D + LT LY++++ C E LL D + +G+ D G+QEIH AC+ GR HLE+LL Y ADIN T+ +GNTPLHI A NQE CA +LLFRGA R + N A SAY A + N ++A I+ Y + +V I P Y+ +RR ++
Sbjct: 9 ERIWLAKLQVISELAKGVKDALNYGFYEPPCNGRSGKFLDEERTFREYPQRVKPAQLEFKYKRRVYKSLQYDAKALQKVHTKGNLKKLLDAVSLGSIPQVTKLTDKGLDPNFQEDKTGETPLTIAAMGDQGMDLIMSLVNGGAHLDYRAGDGLTSVHKAAIKGKVNSLKTLLDLGASPNYRDGKNLTALYYTVLYGADPYCCEILLNDQAEMGVMDHQGMQEIHHACKNGRVQHLEHLLYYGADINV-TNASGNTPLHIAACNNQEDCAHVLLFRGARRDILNYANQSAYNMAAMGGNNDLAEYIRNYHDGQIVKISSKPTYSTRRRKTL 337 HSP 2 Score: 75.0998 bits (183), Expect = 9.740e-14 Identity = 40/83 (48.19%), Postives = 54/83 (65.06%), Query Frame = 1
Query: 1774 PRVVVLQKNSQG-FGFVIRGLKASST-INFRPTLKNPALQYFEEVEVNSVAARAGLKKGDFILEINNLSVVSASHEDTVRLIK 2016
PRVV L + +QG FGF +RG + + ++F+PTL+ PALQY EVE A R G+K DFILE+N V +A+H V LI+
Sbjct: 555 PRVVTLYRGNQGGFGFQMRGANSQTPRLDFQPTLEFPALQYIGEVERGGEADRKGVKCKDFILEVNWEDVTTATHTHVVELIR 637
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Ensembl Nematostella
Match: EDO43690 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RXV8]) HSP 1 Score: 94.7449 bits (234), Expect = 3.981e-21 Identity = 72/234 (30.77%), Postives = 111/234 (47.44%), Query Frame = 1
Query: 523 LFMEHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPL-----------------YHSIISDPAAACTERLLFDYS--------IIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAIL 1149
+F+ V + D+ +V K+L KG D N+Q G T L +AC + + +L+KVLV+ GA +D R + G T LHAAA G++E K L++ G ++ EG PL I D A A E+++ + + I +D+ +H A G + LLQ +IN++ + N TPLH A+ Q+ LL GAD +N+ +QQ L
Sbjct: 52 VFLSAVSSGDVDEVKKLLAKGADINYQ-NVDGLTALHQAC-IDENFDLVKVLVDKGASMDVRDNEGWTSLHAAASCGSVEIAKYLIENGADVAAVNNEGELPLDLAEEEDMEDLLTDEIENQGIDVDDARAVEEKIMLNDAQSWLNKNCINESKDKTEASALHVASSKGYLKVIGLLLQLGVEINAKDADNW-TPLHAAAHWGQKDACELLSENGADFNARNKMVGIDHQQNWL 282
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Ensembl Nematostella
Match: EDO38725 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SC11]) HSP 1 Score: 71.633 bits (174), Expect = 6.768e-14 Identity = 54/159 (33.96%), Postives = 79/159 (49.69%), Query Frame = 1
Query: 622 TPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGAD 1098
TPL AC +E+ ++LVE GA LD ++ G TPLH AA +G+ +A+K LL G + + D TP ++ AA TE + ++ +DEN +H AC GR H+E L + N + + G + LH+ A LL GAD
Sbjct: 38 TPLHVACK-KGSMEVGRLLVEKGAALDKKNDKGETPLHMAACIGSFDALKFLLSKGVAIDERDFSHRTPFLSAV----AAGRTENAM----LLLEKDENQKSPLHLACAAGRALHVEALTRAGLSTN-ERDEEGQSALHMAALSGFRKVVTQLLRYGAD 186
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Ensembl Nematostella
Match: EDO36720 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SHV7]) HSP 1 Score: 72.0182 bits (175), Expect = 1.170e-13 Identity = 67/241 (27.80%), Postives = 114/241 (47.30%), Query Frame = 1
Query: 490 LKKLHSKTNLKLFMEHVGNADIGKVSKMLNKGIDPNFQIK---ETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPL-----YHSII--------------SDPAAA---CTERLLFDYSIIGIEDEN-----GLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAG 1122
LK KT+ +F + V DI +++ ++ F + E G T L +AC T ++L+++LV GA+LD + G + LHAAA+ GNL ++ L+ +G + + G P+ H +I +D A + L+ D I G+++ N G+ +H+ G + +++LL++ A++N Q S NG++PLH C LLL GAD + G
Sbjct: 2 LKFAVRKTSSSIFHDAVARKDIVRLAFLMESN-RRQFNVDLLDEDGLTALQRAC-FTGNLKLVQLLVSYGANLDIQDKEGWSVLHAAAVAGNLSILRYLVAVGADVSVRNDLGELPIDVATDVHCVIVLAEGMKRAGLRKLTDKFFAKRPQLKTLIKDSLIQGLDNVNDLNDSGISLLHEMAGRGDSESVQFLLEHGAEVNRQ-SLNGSSPLHEAVQSGNIDCTLLLLRSGADLYAETDGG 239
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Ensembl Nematostella
Match: EDO39112 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SB40]) HSP 1 Score: 69.3218 bits (168), Expect = 6.178e-12 Identity = 70/238 (29.41%), Postives = 112/238 (47.06%), Query Frame = 1
Query: 499 LHSKTNLKLFMEHVGNA--DIGKVSKMLNKGIDPNFQIKET-GETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLG-QSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSI-IGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYYKNE 1197
+H +T L HV A D V +L G K++ G+TPL A Q ++I++L+E GA++ + PLH AA G L+ + ILL ++ N +D LT L+ + + AC RLL + + D+ L + G ++ LL+Y AD+ ++ KN TPL AY + R LL GAD + +G +A A+ DN N+ + + ++E
Sbjct: 1 MHWRTCL-----HVAAACSDFRTVEIILRNGGKSIINSKDSYGKTPLHYAVIRCQGGKIIQLLIESGANVLAVDFDERLPLHHAAEQGMLDNISILLQANPETINEVDNRSLTALHIAAAAARTEAC--RLLLEKGAEVDYRDDERLTPLFYVASVGCPLTVKVLLEYDADLEAR-DKNRKTPLISAAYFGRLEVFRTLLDSGADIAAETSSGWNALDVAL--DNNNLDITNEIIRHE 228
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Ensembl Medaka
Match: shank3a (SH3 and multiple ankyrin repeat domains 3 [Source:NCBI gene;Acc:101169284]) HSP 1 Score: 322.398 bits (825), Expect = 8.506e-91 Identity = 166/346 (47.98%), Postives = 224/346 (64.74%), Query Frame = 1
Query: 214 IKVPDLNLKKSVSLILTETVGMLKKSLIGTLSNDLKDAMNYGLFIPPTEGKAGKFLQEERPLNDYGLHKVHQI--VELRYKRRLYRCTNLNINKLKKLHSKTNLKLFMEHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYYKNEDVVCIRGSPKYNDKRR 1245
I +PDL K + + + + K+ ++ TL+ LKD +NYGLF P GKAGKFL EER L +Y + + +E RYKRR+Y T L+ +L KLH+K NLK FME+V +I KVS+ L+KG+DPNF +TGE PL + L +LIKVL GGAHLD+R +G T LH A N A+ LLDLG SP+ D GLTPLYH + C E LL D++ +G DENG QEIHQACR+G HLE+LL Y A +++Q + +GNT LH+CA NQESCAR+LLFRGA++ +KN +A+Q AI++ N ++A +I+ +K DVV R +P Y ++RR
Sbjct: 87 IGIPDLQQTKCLKFNVDAPIWLSKQQILCTLNQSLKDVLNYGLFQPAYNGKAGKFLDEERQLREYPFPSIAPVPYLEFRYKRRVYTQTYLDEKQLSKLHTKANLKKFMEYVQQRNIEKVSRFLDKGLDPNFHDPDTGECPLTLSAQLEGCADLIKVLKNGGAHLDFRTKDGITALHKAVRSKNHTALITLLDLGASPDYKDSRGLTPLYHCSMVGGDPYCCELLLHDHAQVGCVDENGWQEIHQACRYGHVQHLEHLLFYGAVMSAQNA-SGNTALHVCALYNQESCARVLLFRGANKEIKNYNSQTAFQVAIIAGNFDLAEIIKVHKASDVVPFRETPSYTNRRR 431 HSP 2 Score: 89.3521 bits (220), Expect = 1.739e-17 Identity = 48/101 (47.52%), Postives = 66/101 (65.35%), Query Frame = 1
Query: 1780 VVVLQKNSQGFGFVIRGLKASSTIN-FRPTLKNPALQYFEEVEVNSVAARAGLKKGDFILEINNLSVVSASHEDTVRLIKASGDILAMKVVTVNKDKLDEQ 2079
V+ +K ++GFGFV+RG KA + I F PT PALQY E V+V VA RAGL+ GDF++E+N ++VV H+ V LI+ G L MKVV+V + E+
Sbjct: 690 AVLHKKENEGFGFVLRGAKAETPIEEFTPTPAFPALQYLESVDVEGVAWRAGLRTGDFLIEVNGVNVVKVGHKQVVSLIRQGGSRLLMKVVSVTRKPESEE 790
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Ensembl Medaka
Match: shank3a (SH3 and multiple ankyrin repeat domains 3 [Source:NCBI gene;Acc:101169284]) HSP 1 Score: 322.013 bits (824), Expect = 1.277e-90 Identity = 166/346 (47.98%), Postives = 224/346 (64.74%), Query Frame = 1
Query: 214 IKVPDLNLKKSVSLILTETVGMLKKSLIGTLSNDLKDAMNYGLFIPPTEGKAGKFLQEERPLNDYGLHKVHQI--VELRYKRRLYRCTNLNINKLKKLHSKTNLKLFMEHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYYKNEDVVCIRGSPKYNDKRR 1245
I +PDL K + + + + K+ ++ TL+ LKD +NYGLF P GKAGKFL EER L +Y + + +E RYKRR+Y T L+ +L KLH+K NLK FME+V +I KVS+ L+KG+DPNF +TGE PL + L +LIKVL GGAHLD+R +G T LH A N A+ LLDLG SP+ D GLTPLYH + C E LL D++ +G DENG QEIHQACR+G HLE+LL Y A +++Q + +GNT LH+CA NQESCAR+LLFRGA++ +KN +A+Q AI++ N ++A +I+ +K DVV R +P Y ++RR
Sbjct: 87 IGIPDLQQTKCLKFNVDAPIWLSKQQILCTLNQSLKDVLNYGLFQPAYNGKAGKFLDEERQLREYPFPSIAPVPYLEFRYKRRVYTQTYLDEKQLSKLHTKANLKKFMEYVQQRNIEKVSRFLDKGLDPNFHDPDTGECPLTLSAQLEGCADLIKVLKNGGAHLDFRTKDGITALHKAVRSKNHTALITLLDLGASPDYKDSRGLTPLYHCSMVGGDPYCCELLLHDHAQVGCVDENGWQEIHQACRYGHVQHLEHLLFYGAVMSAQNA-SGNTALHVCALYNQESCARVLLFRGANKEIKNYNSQTAFQVAIIAGNFDLAEIIKVHKASDVVPFRETPSYTNRRR 431 HSP 2 Score: 89.3521 bits (220), Expect = 1.943e-17 Identity = 48/101 (47.52%), Postives = 66/101 (65.35%), Query Frame = 1
Query: 1780 VVVLQKNSQGFGFVIRGLKASSTIN-FRPTLKNPALQYFEEVEVNSVAARAGLKKGDFILEINNLSVVSASHEDTVRLIKASGDILAMKVVTVNKDKLDEQ 2079
V+ +K ++GFGFV+RG KA + I F PT PALQY E V+V VA RAGL+ GDF++E+N ++VV H+ V LI+ G L MKVV+V + E+
Sbjct: 690 AVLHKKENEGFGFVLRGAKAETPIEEFTPTPAFPALQYLESVDVEGVAWRAGLRTGDFLIEVNGVNVVKVGHKQVVSLIRQGGSRLLMKVVSVTRKPESEE 790
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Ensembl Medaka
Match: shank3a (SH3 and multiple ankyrin repeat domains 3 [Source:NCBI gene;Acc:101169284]) HSP 1 Score: 317.775 bits (813), Expect = 2.078e-89 Identity = 165/355 (46.48%), Postives = 224/355 (63.10%), Query Frame = 1
Query: 187 NNNQCFKFEIKVPDLNLKKSVSLILTETVGMLKKSLIGTLSNDLKDAMNYGLFIPPTEGKAGKFLQEERPLNDYGLHKVHQI--VELRYKRRLYRCTNLNINKLKKLHSKTNLKLFMEHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYYKNEDVVCIRGSPKYNDKRR 1245
++ +C KF + P + + K+ ++ TL+ LKD +NYGLF P GKAGKFL EER L +Y + + +E RYKRR+Y T L+ +L KLH+K NLK FME+V +I KVS+ L+KG+DPNF +TGE PL + L +LIKVL GGAHLD+R +G T LH A N A+ LLDLG SP+ D GLTPLYH + C E LL D++ +G DENG QEIHQACR+G HLE+LL Y A +++Q + +GNT LH+CA NQESCAR+LLFRGA++ +KN +A+Q AI++ N ++A +I+ +K DVV R +P Y ++RR
Sbjct: 28 SDTKCLKFNVDAP---------------IWLSKQQILCTLNQSLKDVLNYGLFQPAYNGKAGKFLDEERQLREYPFPSIAPVPYLEFRYKRRVYTQTYLDEKQLSKLHTKANLKKFMEYVQQRNIEKVSRFLDKGLDPNFHDPDTGECPLTLSAQLEGCADLIKVLKNGGAHLDFRTKDGITALHKAVRSKNHTALITLLDLGASPDYKDSRGLTPLYHCSMVGGDPYCCELLLHDHAQVGCVDENGWQEIHQACRYGHVQHLEHLLFYGAVMSAQNA-SGNTALHVCALYNQESCARVLLFRGANKEIKNYNSQTAFQVAIIAGNFDLAEIIKVHKASDVVPFRETPSYTNRRR 366 HSP 2 Score: 89.3521 bits (220), Expect = 2.084e-17 Identity = 48/101 (47.52%), Postives = 66/101 (65.35%), Query Frame = 1
Query: 1780 VVVLQKNSQGFGFVIRGLKASSTIN-FRPTLKNPALQYFEEVEVNSVAARAGLKKGDFILEINNLSVVSASHEDTVRLIKASGDILAMKVVTVNKDKLDEQ 2079
V+ +K ++GFGFV+RG KA + I F PT PALQY E V+V VA RAGL+ GDF++E+N ++VV H+ V LI+ G L MKVV+V + E+
Sbjct: 585 AVLHKKENEGFGFVLRGAKAETPIEEFTPTPAFPALQYLESVDVEGVAWRAGLRTGDFLIEVNGVNVVKVGHKQVVSLIRQGGSRLLMKVVSVTRKPESEE 685
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Ensembl Medaka
Match: shank1 (SH3 and multiple ankyrin repeat domains protein 1 [Source:NCBI gene;Acc:101165307]) HSP 1 Score: 307.76 bits (787), Expect = 6.423e-86 Identity = 158/360 (43.89%), Postives = 232/360 (64.44%), Query Frame = 1
Query: 208 FEIKVPDLNLKKSVSLILTETVGMLKKSLIGTLSNDLKDAMNYGLFIPPTEGKAGKFLQEERPLNDY--GLHKVHQIVELRYKRRLYRCTNLNINKLKKLHSKTNLKLFMEHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPV--ELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYYKNEDVVCIRGSPKYNDKRRPSVATSTFLH 1275
F I +PD+ K + TV K+ ++ +L+ L+D +NYGLF P T+G KFL+EER L +Y K +E RYK R+Y+ TNL+ +L KLH+K +LK FM+++ + + K++K L+KG+DPN+Q +TGETPL A +P E I+VLV+GGAH+D+R +G TPLH A + A+ +LL LG SP+ D+ GLTPLYH++++ +C E +L+ + +GI DENG E HQAC+ G + HLE+LL Y AD +SQ + +GNT LHICA N+ESCAR+LL+RGA + KN +G + +Q A++S + + +I+ +++ DVV SPKY +RR S T H
Sbjct: 149 FRIGIPDIKQTKCLRFNPDATVWKAKQQVLCSLTESLRDVLNYGLFQPATDGHDAKFLEEERLLREYPQSFEKGVPYLEFRYKTRVYKQTNLDEKQLAKLHTKASLKKFMDYIQTSAVDKMAKFLDKGLDPNYQDADTGETPLTLAVQC-EPGGGEAIRVLVDGGAHIDFRAKDGLTPLHKAVRGHHHTALLVLLSLGASPDYKDRRGLTPLYHTVLTGGDTSCCETMLYHRAKLGIRDENGWDETHQACQNGNSQHLEHLLFYGADSSSQNA-SGNTALHICALYNKESCARILLYRGASKDTKNNSGQTPFQVAVMSGHFELGEIIKNHRDVDVVPFVESPKYAPQRRDSSRTLAVPH 506 HSP 2 Score: 94.3597 bits (233), Expect = 6.239e-19 Identity = 49/105 (46.67%), Postives = 67/105 (63.81%), Query Frame = 1
Query: 1780 VVVLQKNSQGFGFVIRGLKASSTIN-FRPTLKNPALQYFEEVEVNSVAARAGLKKGDFILEINNLSVVSASHEDTVRLIKASGDILAMKVVTV--NKDKLDEQRK 2085
V++ +K+S+GFGFV+RG KA + I F PT PALQY E V+ VA RAGL+ GDF++E+N +VV H V +I+ G+ L +KVV V N D + RK
Sbjct: 702 VLLQKKDSEGFGFVLRGAKAQTPIEEFTPTPAFPALQYLESVDEGGVAWRAGLRMGDFLIEVNGQNVVKVGHRQVVNMIRQGGNSLMVKVVMVTRNPDMEEGSRK 806
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Ensembl Medaka
Match: shank1 (SH3 and multiple ankyrin repeat domains protein 1 [Source:NCBI gene;Acc:101165307]) HSP 1 Score: 307.76 bits (787), Expect = 6.489e-86 Identity = 158/360 (43.89%), Postives = 232/360 (64.44%), Query Frame = 1
Query: 208 FEIKVPDLNLKKSVSLILTETVGMLKKSLIGTLSNDLKDAMNYGLFIPPTEGKAGKFLQEERPLNDY--GLHKVHQIVELRYKRRLYRCTNLNINKLKKLHSKTNLKLFMEHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPV--ELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYYKNEDVVCIRGSPKYNDKRRPSVATSTFLH 1275
F I +PD+ K + TV K+ ++ +L+ L+D +NYGLF P T+G KFL+EER L +Y K +E RYK R+Y+ TNL+ +L KLH+K +LK FM+++ + + K++K L+KG+DPN+Q +TGETPL A +P E I+VLV+GGAH+D+R +G TPLH A + A+ +LL LG SP+ D+ GLTPLYH++++ +C E +L+ + +GI DENG E HQAC+ G + HLE+LL Y AD +SQ + +GNT LHICA N+ESCAR+LL+RGA + KN +G + +Q A++S + + +I+ +++ DVV SPKY +RR S T H
Sbjct: 149 FRIGIPDIKQTKCLRFNPDATVWKAKQQVLCSLTESLRDVLNYGLFQPATDGHDAKFLEEERLLREYPQSFEKGVPYLEFRYKTRVYKQTNLDEKQLAKLHTKASLKKFMDYIQTSAVDKMAKFLDKGLDPNYQDADTGETPLTLAVQC-EPGGGEAIRVLVDGGAHIDFRAKDGLTPLHKAVRGHHHTALLVLLSLGASPDYKDRRGLTPLYHTVLTGGDTSCCETMLYHRAKLGIRDENGWDETHQACQNGNSQHLEHLLFYGADSSSQNA-SGNTALHICALYNKESCARILLYRGASKDTKNNSGQTPFQVAVMSGHFELGEIIKNHRDVDVVPFVESPKYAPQRRDSSRTLAVPH 506 HSP 2 Score: 94.3597 bits (233), Expect = 6.401e-19 Identity = 49/105 (46.67%), Postives = 67/105 (63.81%), Query Frame = 1
Query: 1780 VVVLQKNSQGFGFVIRGLKASSTIN-FRPTLKNPALQYFEEVEVNSVAARAGLKKGDFILEINNLSVVSASHEDTVRLIKASGDILAMKVVTV--NKDKLDEQRK 2085
V++ +K+S+GFGFV+RG KA + I F PT PALQY E V+ VA RAGL+ GDF++E+N +VV H V +I+ G+ L +KVV V N D + RK
Sbjct: 702 VLLQKKDSEGFGFVLRGAKAQTPIEEFTPTPAFPALQYLESVDEGGVAWRAGLRMGDFLIEVNGQNVVKVGHRQVVNMIRQGGNSLMVKVVMVTRNPDMEEGSRK 806
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Planmine SMEST
Match: SMESG000014775.1 (SMESG000014775.1) HSP 1 Score: 1739.55 bits (4504), Expect = 0.000e+0 Identity = 994/995 (99.90%), Postives = 995/995 (100.00%), Query Frame = 1
Query: 160 HYGSSVATNNNNQCFKFEIKVPDLNLKKSVSLILTETVGMLKKSLIGTLSNDLKDAMNYGLFIPPTEGKAGKFLQEERPLNDYGLHKVHQIVELRYKRRLYRCTNLNINKLKKLHSKTNLKLFMEHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYYKNEDVVCIRGSPKYNDKRRPSVATSTFLHRSRSASRIMDISQVDKREDSGFNSQIGHYPDHLKNQHRSLGKAGGQIFTHKFQETDKPNNSQSESIFESKMLSRSVNNLQQXXXXXXXXXXXXXXXXXXCFSNWWLDWENDETDRVSSVSGPXXXXXXXXXXXXGDXXXXXXXXXXXXXXXXXDLSGLVDIDTSFLPRVVVLQKNSQGFGFVIRGLKASSTINFRPTLKNPALQYFEEVEVNSVAARAGLKKGDFILEINNLSVVSASHEDTVRLIKASGDILAMKVVTVNKDKLDEQRKCYDYAXXXXXXXXXXXXXXXXXXXXXXXXTFSRSMNRPVSNTMANPNIYPTVNINSSIAPYKPVFNTPSVMINNQISPFILSQSKMNMNDGIRVRRNTIASNEMRPDSILSTDSFYXXXXXXLSDFSPQQQIEKEVVDDFTLKRSKTYPSSAIYLDEKSDSNPGMTCLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKPILKQTKTLPKPSSSMINQPLEFDSHLRQALAKRRQQIDNDHSSVASFETGDTIGRNSLRTTPNNLKQNDTHGRANPNKWNNHNDKITDSSNFNSNNPFQRSRSDVYSANNGNVVRKTEDNNSRLYLV 3144
HYGSSVATNNNNQCFKFEIKVPDLNLKKSVSLILTETVGMLKKSLIGTLSNDLKDAMNYGLFIPPTEGKAGKFLQEERPLNDYGLHKVHQIVELRYKRRLYRCTNLNINKLKKLHSKTNLKLFMEHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYYK+EDVVCIRGSPKYNDKRRPSVATSTFLHRSRSASRIMDISQVDKREDSGFNSQIGHYPDHLKNQHRSLGKAGGQIFTHKFQETDKPNNSQSESIFESKMLSRSVNNLQQIPKKIEPPSIEPNESASSCFSNWWLDWENDETDRVSSVSGPSQRRTARTQSRQGDSKKKSRSQSCKRRSSKSDLSGLVDIDTSFLPRVVVLQKNSQGFGFVIRGLKASSTINFRPTLKNPALQYFEEVEVNSVAARAGLKKGDFILEINNLSVVSASHEDTVRLIKASGDILAMKVVTVNKDKLDEQRKCYDYAMSSMDDSSDQSSIISSELRSQRLSTFSRSMNRPVSNTMANPNIYPTVNINSSIAPYKPVFNTPSVMINNQISPFILSQSKMNMNDGIRVRRNTIASNEMRPDSILSTDSFYPMPPPPLSDFSPQQQIEKEVVDDFTLKRSKTYPSSAIYLDEKSDSNPGMTCLPISNVPPVTAPPPPPPPTLAAPPPPPAPPPPGPPPIMGISSHSSSIPQSVSISNIPKPILKQTKTLPKPSSSMINQPLEFDSHLRQALAKRRQQIDNDHSSVASFETGDTIGRNSLRTTPNNLKQNDTHGRANPNKWNNHNDKITDSSNFNSNNPFQRSRSDVYSANNGNVVRKTEDNNSRLYLV
Sbjct: 18 HYGSSVATNNNNQCFKFEIKVPDLNLKKSVSLILTETVGMLKKSLIGTLSNDLKDAMNYGLFIPPTEGKAGKFLQEERPLNDYGLHKVHQIVELRYKRRLYRCTNLNINKLKKLHSKTNLKLFMEHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYYKDEDVVCIRGSPKYNDKRRPSVATSTFLHRSRSASRIMDISQVDKREDSGFNSQIGHYPDHLKNQHRSLGKAGGQIFTHKFQETDKPNNSQSESIFESKMLSRSVNNLQQIPKKIEPPSIEPNESASSCFSNWWLDWENDETDRVSSVSGPSQRRTARTQSRQGDSKKKSRSQSCKRRSSKSDLSGLVDIDTSFLPRVVVLQKNSQGFGFVIRGLKASSTINFRPTLKNPALQYFEEVEVNSVAARAGLKKGDFILEINNLSVVSASHEDTVRLIKASGDILAMKVVTVNKDKLDEQRKCYDYAMSSMDDSSDQSSIISSELRSQRLSTFSRSMNRPVSNTMANPNIYPTVNINSSIAPYKPVFNTPSVMINNQISPFILSQSKMNMNDGIRVRRNTIASNEMRPDSILSTDSFYPMPPPPLSDFSPQQQIEKEVVDDFTLKRSKTYPSSAIYLDEKSDSNPGMTCLPISNVPPVTAPPPPPPPTLAAPPPPPAPPPPGPPPIMGISSHSSSIPQSVSISNIPKPILKQTKTLPKPSSSMINQPLEFDSHLRQALAKRRQQIDNDHSSVASFETGDTIGRNSLRTTPNNLKQNDTHGRANPNKWNNHNDKITDSSNFNSNNPFQRSRSDVYSANNGNVVRKTEDNNSRLYLV 1012
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Planmine SMEST
Match: SMESG000014775.1 (SMESG000014775.1) HSP 1 Score: 1692.94 bits (4383), Expect = 0.000e+0 Identity = 977/995 (98.19%), Postives = 979/995 (98.39%), Query Frame = 1
Query: 160 HYGSSVATNNNNQCFKFEIKVPDLNLKKSVSLILTETVGMLKKSLIGTLSNDLKDAMNYGLFIPPTEGKAGKFLQEERPLNDYGLHKVHQIVELRYKRRLYRCTNLNINKLKKLHSKTNLKLFMEHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYYKNEDVVCIRGSPKYNDKRRPSVATSTFLHRSRSASRIMDISQVDKREDSGFNSQIGHYPDHLKNQHRSLGKAGGQIFTHKFQETDKPNNSQSESIFESKMLSRSVNNLQQXXXXXXXXXXXXXXXXXXCFSNWWLDWENDETDRVSSVSGPXXXXXXXXXXXXGDXXXXXXXXXXXXXXXXXDLSGLVDIDTSFLPRVVVLQKNSQGFGFVIRGLKASSTINFRPTLKNPALQYFEEVEVNSVAARAGLKKGDFILEINNLSVVSASHEDTVRLIKASGDILAMKVVTVNKDKLDEQRKCYDYAXXXXXXXXXXXXXXXXXXXXXXXXTFSRSMNRPVSNTMANPNIYPTVNINSSIAPYKPVFNTPSVMINNQISPFILSQSKMNMNDGIRVRRNTIASNEMRPDSILSTDSFYXXXXXXLSDFSPQQQIEKEVVDDFTLKRSKTYPSSAIYLDEKSDSNPGMTCLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKPILKQTKTLPKPSSSMINQPLEFDSHLRQALAKRRQQIDNDHSSVASFETGDTIGRNSLRTTPNNLKQNDTHGRANPNKWNNHNDKITDSSNFNSNNPFQRSRSDVYSANNGNVVRKTEDNNSRLYLV 3144
HYGSSVATNNNNQCFKFEIKVPDLNLKKSVSLILTETVGMLKKSLIGTLSNDLKDAMNYGLFIPPTEGKAGKFLQEERPLNDYGLHKVHQIVELRYKRRLYRCTNLNINKLKKLHSKTNLKLFMEHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYYK+EDVVCIRGSPKYNDKRRPSVATSTFLHRSRSASRIMDISQVDKREDSGFNSQIGHYPDHLKNQHRSLGKAGGQIFTHKFQETDKPNNSQSESIFESKMLSRSVNNLQQIPKKIEPPSIEPNESASSCFSNWWLDWENDETDRVSSVSGPSQRRTARTQSRQGDSKKKSRSQSCKRRSSKSDLSGLVDIDTSFLPRVVVLQKNSQGFGFVIRGLKASSTINFRPTLKNPALQYFEEVEVNSVAARAGLKKGDFILEINNLSVVSASHEDTVRLIKASGDILAMKVVTVNKDKLDEQRKCYDYAMSSMDDSSDQSSIISSELRSQRLSTFSRSMNRPVSNTMANPNIYPTVNINSSIAPYKPVFNTPSVMINNQISPFILSQSKMNMNDGIRVRRNTIASNEMRPDSILSTDSFYPMPPPPLSDFSPQQQIEKEVVDDFTLKRSKTYPSSAIYLDEKSDSNPGMTCLPISNVPPVTAPPPPPPPTLAAPPPPPAPPPPGPPPIMGISSHSSSIPQSVSISNIPKPILKQTKTLPKPSSSMINQPLEFDSHLRQALAKRRQQIDNDHSSVASFETGDTIGRNSLRTTPNNLKQNDTHGRANP N+NNPFQRSRSDVYSANNGNVVRKTEDNNSRLYLV
Sbjct: 18 HYGSSVATNNNNQCFKFEIKVPDLNLKKSVSLILTETVGMLKKSLIGTLSNDLKDAMNYGLFIPPTEGKAGKFLQEERPLNDYGLHKVHQIVELRYKRRLYRCTNLNINKLKKLHSKTNLKLFMEHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYYKDEDVVCIRGSPKYNDKRRPSVATSTFLHRSRSASRIMDISQVDKREDSGFNSQIGHYPDHLKNQHRSLGKAGGQIFTHKFQETDKPNNSQSESIFESKMLSRSVNNLQQIPKKIEPPSIEPNESASSCFSNWWLDWENDETDRVSSVSGPSQRRTARTQSRQGDSKKKSRSQSCKRRSSKSDLSGLVDIDTSFLPRVVVLQKNSQGFGFVIRGLKASSTINFRPTLKNPALQYFEEVEVNSVAARAGLKKGDFILEINNLSVVSASHEDTVRLIKASGDILAMKVVTVNKDKLDEQRKCYDYAMSSMDDSSDQSSIISSELRSQRLSTFSRSMNRPVSNTMANPNIYPTVNINSSIAPYKPVFNTPSVMINNQISPFILSQSKMNMNDGIRVRRNTIASNEMRPDSILSTDSFYPMPPPPLSDFSPQQQIEKEVVDDFTLKRSKTYPSSAIYLDEKSDSNPGMTCLPISNVPPVTAPPPPPPPTLAAPPPPPAPPPPGPPPIMGISSHSSSIPQSVSISNIPKPILKQTKTLPKPSSSMINQPLEFDSHLRQALAKRRQQIDNDHSSVASFETGDTIGRNSLRTTPNNLKQNDTHGRANP----------------NNNNPFQRSRSDVYSANNGNVVRKTEDNNSRLYLV 996
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Planmine SMEST
Match: SMESG000018129.1 (SMESG000018129.1) HSP 1 Score: 311.227 bits (796), Expect = 4.444e-90 Identity = 165/347 (47.55%), Postives = 224/347 (64.55%), Query Frame = 1
Query: 214 IKVPDLNLKKSVSLILTETVGMLKKSLIGTLSNDLKDAMNYGLFIPPTEGKAGKFLQEERPLNDYGLHKVHQIVELRYKRRLYRCTNLNIN---KLKKLHSKTNLKLFMEHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYYKNEDVVCIRGSPKYNDKRR 1245
I +P+ N+++++ L ETV LK ++ L DL+D NYG F+P GK GKFLQEER LN H ++E +K L R +N + KLKK + K+N K F+ ++ + ++ K++K LN G+DPNF + ETPL AC L P ++I LV GA+LD+R S+ T LH A G + +K LL LGQSPN D +G TPLY+ I +D C LL+++SI+GI DE G QEIH+AC +GRT HL++LL Y ADI+++T+K GNT LHICA NQ SCARLLL+RG R + SAYQ A+LS+N IA LIQ +K+EDVV + PK+N+KRR
Sbjct: 19 ISIPEKNIERNIEWNLNETVESLKYYILKLLP-DLEDPFNYGFFLPDNNGKVGKFLQEERVLN-------HYLIEAPFKLELQRKMRINFSNSSKLKKFNIKSNQKQFIVYIKHGELMKINKFLNNGLDPNFHVTGIPETPLTLACRLLDPHKIIMALVSNGAYLDFRASDSLTALHKVAKEGLYQPMKTLLQLGQSPNCKDNKGYTPLYYCIENDAPQECVNLLLYEHSIMGIRDEQGFQEIHKACLYGRTVHLDHLLTYGADIDAKTNK-GNTALHICAVHNQGSCARLLLYRGITRYALDCENKSAYQTALLSNNLEIADLIQNFKDEDVVPVTTLPKFNEKRR 356 HSP 2 Score: 87.0409 bits (214), Expect = 4.643e-17 Identity = 47/120 (39.17%), Postives = 69/120 (57.50%), Query Frame = 1
Query: 1741 SGLVDIDTSFLPRVVVLQKNSQGFGFVIRGLKASSTINFRPTLKNPALQYFEEVEVNSVAARAGLKKGDFILEINNLSVVSASHEDTVRLIKASGDILAMKVVTVNKDKLDEQRKCYDYA 2100
+ ++D +PR VLQK +GFGFVI+G K S I+ N A QYF+ + S A AGL GDF+LE+N + V HE V++I+ +GD L +K++TV D + + +D A
Sbjct: 436 TSIIDSKLENVPRTTVLQKGPRGFGFVIKGFKNESEIS--SMAHNLATQYFDCIAEESPAFYAGLLTGDFLLEVNGVDVHEMPHESVVKVIQNAGDFLTLKIITV--DHITNSQAIFDNA 551
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Planmine SMEST
Match: SMESG000078048.1 (SMESG000078048.1) HSP 1 Score: 280.026 bits (715), Expect = 1.195e-79 Identity = 147/351 (41.88%), Postives = 218/351 (62.11%), Query Frame = 1
Query: 208 FEIKVPDLNLKKSVSLILTETVGMLK--KSLIGTLSNDLKDAMNYGLFIPPTEGKAGKFLQEERPLNDYGLHKVHQIVELRYKRRLYRCTNLNINKLKKLHSKTNLKLFMEHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYYKNEDVVCIRG-SPKYNDKRRPS 1251
F +KV ++LKK + + + + ++++ + L D MNYGLFIP KAGKFL+EER L+DY +E +YK ++ + KK++SK N F++++ D KV K L+KG+DPNF +GETPL + +P+E+I LV GGAHLDYR +G TPLH AAI GN E V LL+ G S N +D G+TPLY++++ D + C E+LL + + +G+ D+ GL+EIHQACR G++ HL+ LL Y A+INS+T + +TPLH+ AY QE C RLLL RGADR++ N +G +A Q+A + K I+ +I+ +K+ ++ P +N R+ S
Sbjct: 29 FSLKVSIIDLKKEAKYEFSNAISVFEIHRNILRKYGSRLNDPMNYGLFIPHQVNKAGKFLKEERWLSDYCSSNTMNHLEFQYKHKIVWPDKSQGDLHKKINSKVNHTRFIDYIIRNDPVKVQKALDKGLDPNFHC-SSGETPLTLTAKVNKPLEIITALVSGGAHLDYRSVDGLTPLHKAAISGNYETVTALLNFGTSANCLDSNGMTPLYYNLLYDNSTKCLEKLLHERAKLGVVDKRGLKEIHQACRSGKSDHLDILLAYGAEINSRTETHLSTPLHVAAYTGQEDCVRLLLLRGADRSLVNSSGRTAAQEARATGYKQISNMIKDFKDSEIHTQPSFKPTWNSHRKTS 378
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Planmine SMEST
Match: SMESG000078048.1 (SMESG000078048.1) HSP 1 Score: 280.411 bits (716), Expect = 1.214e-79 Identity = 147/351 (41.88%), Postives = 218/351 (62.11%), Query Frame = 1
Query: 208 FEIKVPDLNLKKSVSLILTETVGMLK--KSLIGTLSNDLKDAMNYGLFIPPTEGKAGKFLQEERPLNDYGLHKVHQIVELRYKRRLYRCTNLNINKLKKLHSKTNLKLFMEHVGNADIGKVSKMLNKGIDPNFQIKETGETPLIKACSLTQPVELIKVLVEGGAHLDYRHSNGHTPLHAAAILGNLEAVKILLDLGQSPNTIDQEGLTPLYHSIISDPAAACTERLLFDYSIIGIEDENGLQEIHQACRFGRTHHLEYLLQYRADINSQTSKNGNTPLHICAYLNQESCARLLLFRGADRTVKNRAGHSAYQQAILSDNKNIAMLIQYYKNEDVVCIRG-SPKYNDKRRPS 1251
F +KV ++LKK + + + + ++++ + L D MNYGLFIP KAGKFL+EER L+DY +E +YK ++ + KK++SK N F++++ D KV K L+KG+DPNF +GETPL + +P+E+I LV GGAHLDYR +G TPLH AAI GN E V LL+ G S N +D G+TPLY++++ D + C E+LL + + +G+ D+ GL+EIHQACR G++ HL+ LL Y A+INS+T + +TPLH+ AY QE C RLLL RGADR++ N +G +A Q+A + K I+ +I+ +K+ ++ P +N R+ S
Sbjct: 47 FSLKVSIIDLKKEAKYEFSNAISVFEIHRNILRKYGSRLNDPMNYGLFIPHQVNKAGKFLKEERWLSDYCSSNTMNHLEFQYKHKIVWPDKSQGDLHKKINSKVNHTRFIDYIIRNDPVKVQKALDKGLDPNFHC-SSGETPLTLTAKVNKPLEIITALVSGGAHLDYRSVDGLTPLHKAAISGNYETVTALLNFGTSANCLDSNGMTPLYYNLLYDNSTKCLEKLLHERAKLGVVDKRGLKEIHQACRSGKSDHLDILLAYGAEINSRTETHLSTPLHVAAYTGQEDCVRLLLLRGADRSLVNSSGRTAAQEARATGYKQISNMIKDFKDSEIHTQPSFKPTWNSHRKTS 396 The following BLAST results are available for this feature:
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of SH3 and multiple ankyrin repeat domains protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of SH3 and multiple ankyrin repeat domains protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 2
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of SH3 and multiple ankyrin repeat domains protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30019342 ID=SMED30019342|Name=SH3 and multiple ankyrin repeat domains protein|organism=Schmidtea mediterranea sexual|type=transcript|length=3373bpback to top protein sequence of SMED30019342-orf-1 >SMED30019342-orf-1 ID=SMED30019342-orf-1|Name=SMED30019342-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1013bp MSICDSDSGLSISLDGSHYGSSVATNNNNQCFKFEIKVPDLNLKKSVSLIback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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