Clathrin light chain

Overview
NameClathrin light chain
Smed IDSMED30019324
Length (bp)751
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Clathrin light chain (SMED30019324) t-SNE clustered cells

Violin plots show distribution of expression levels for Clathrin light chain (SMED30019324) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Clathrin light chain (SMED30019324) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Clathrin light chain (SMED30019324) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30019324

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 7

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
Smed sexual biotypeSMED30019324h1SMcG0001359 Contig48744uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30019324h1SMcG0001359 Contig48744newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
nervous systemSMED30019324h1SMcG0001359 dd_Smed_v4_2973_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30019324h1SMcG0001359 dd_Smed_v4_2973_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neuronSMED30019324h1SMcG0001359 dd_Smed_v4_2973_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		whole organism asexual adult colorimetric in situ hybridization evidence
muscle cellSMED30019324h1SMcG0001359 dd_Smed_v4_2973_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30019324h1SMcG0001359 dd_Smed_v6_2973_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Clathrin light chain vs. Ensembl Human
Match: CLTA (clathrin light chain A [Source:HGNC Symbol;Acc:HGNC:2090])

HSP 1 Score: 72.4034 bits (176), Expect = 1.075e-14
Identity = 46/130 (35.38%), Postives = 69/130 (53.08%), Query Frame = 3 
Query:  216 EPEKIKKWREEFKSRLEIKDKNEQQKIEDLEMTANKELHDWCLRYREQLRITVKNNREDNARLVMEQTKINETASKNDYHVKETKIWESICKMCNFKPXXXXXXXXXPQNVKEATRMRELLMSLRHQPLV 605
            EPE I+KWREE   RLE  D N +++  + +  A KEL +W  R  EQL+ T  NNR      V     I+E++   +        WE + ++C+F P S+       +  K+ +RMR +L+SL+  PLV
Sbjct:  106 EPESIRKWREEQMERLEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNRAAEEAFV---NDIDESSPGTE--------WERVARLCDFNPKSS-------KQAKDVSRMRSVLISLKQAPLV 217
[Close]
BLAST of Clathrin light chain vs. Ensembl Human
Match: CLTA (clathrin light chain A [Source:HGNC Symbol;Acc:HGNC:2090])

HSP 1 Score: 69.3218 bits (168), Expect = 1.441e-13
Identity = 46/131 (35.11%), Postives = 67/131 (51.15%), Query Frame = 3 
Query:  216 EPEKIKKWREEFKSRLEIKDKNEQQKIEDLEMTANKELHDWCLRYREQLRITVKNNREDNARLVMEQTKINETASKNDYHVKETKI-WESICKMCNFKPXXXXXXXXXPQNVKEATRMRELLMSLRHQPLV 605
            EPE I+KWREE   RLE  D N +++  + +  A KEL +W  R  EQL+ T  NN  +         +  E A  ND         WE + ++C+F P S+       +  K+ +RMR +L+SL+  PLV
Sbjct:  106 EPESIRKWREEQMERLEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNSTNINHPCYSLEQAAEEAFVNDIDESSPGTEWERVARLCDFNPKSS-------KQAKDVSRMRSVLISLKQAPLV 229
[Close]
BLAST of Clathrin light chain vs. Ensembl Human
Match: CLTA (clathrin light chain A [Source:HGNC Symbol;Acc:HGNC:2090])

HSP 1 Score: 69.3218 bits (168), Expect = 1.441e-13
Identity = 46/131 (35.11%), Postives = 67/131 (51.15%), Query Frame = 3 
Query:  216 EPEKIKKWREEFKSRLEIKDKNEQQKIEDLEMTANKELHDWCLRYREQLRITVKNNREDNARLVMEQTKINETASKNDYHVKETKI-WESICKMCNFKPXXXXXXXXXPQNVKEATRMRELLMSLRHQPLV 605
            EPE I+KWREE   RLE  D N +++  + +  A KEL +W  R  EQL+ T  NN  +         +  E A  ND         WE + ++C+F P S+       +  K+ +RMR +L+SL+  PLV
Sbjct:  106 EPESIRKWREEQMERLEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNSTNINHPCYSLEQAAEEAFVNDIDESSPGTEWERVARLCDFNPKSS-------KQAKDVSRMRSVLISLKQAPLV 229
[Close]
BLAST of Clathrin light chain vs. Ensembl Human
Match: CLTA (clathrin light chain A [Source:HGNC Symbol;Acc:HGNC:2090])

HSP 1 Score: 68.1662 bits (165), Expect = 4.602e-13
Identity = 51/149 (34.23%), Postives = 73/149 (48.99%), Query Frame = 3 
Query:  216 EPEKIKKWREEFKSRLEIKDKNEQQKIEDLEMTANKELHDWCLRYREQLRITVKNNREDN--------ARLVMEQTKIN----------ETASKNDYHVKETKI-WESICKMCNFKPXXXXXXXXXPQNVKEATRMRELLMSLRHQPLV 605
            EPE I+KWREE   RLE  D N +++  + +  A KEL +W  R  EQL+ T  NNR  +        A ++   T IN          E A  ND         WE + ++C+F P S+       +  K+ +RMR +L+SL+  PLV
Sbjct:  106 EPESIRKWREEQMERLEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNRVADEAFYKQPFADVIGYVTNINHPCYSLEQAAEEAFVNDIDESSPGTEWERVARLCDFNPKSS-------KQAKDVSRMRSVLISLKQAPLV 247
[Close]
BLAST of Clathrin light chain vs. Ensembl Human
Match: CLTA (clathrin light chain A [Source:HGNC Symbol;Acc:HGNC:2090])

HSP 1 Score: 68.1662 bits (165), Expect = 4.602e-13
Identity = 51/149 (34.23%), Postives = 73/149 (48.99%), Query Frame = 3 
Query:  216 EPEKIKKWREEFKSRLEIKDKNEQQKIEDLEMTANKELHDWCLRYREQLRITVKNNREDN--------ARLVMEQTKIN----------ETASKNDYHVKETKI-WESICKMCNFKPXXXXXXXXXPQNVKEATRMRELLMSLRHQPLV 605
            EPE I+KWREE   RLE  D N +++  + +  A KEL +W  R  EQL+ T  NNR  +        A ++   T IN          E A  ND         WE + ++C+F P S+       +  K+ +RMR +L+SL+  PLV
Sbjct:  106 EPESIRKWREEQMERLEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNRVADEAFYKQPFADVIGYVTNINHPCYSLEQAAEEAFVNDIDESSPGTEWERVARLCDFNPKSS-------KQAKDVSRMRSVLISLKQAPLV 247
[Close]
BLAST of Clathrin light chain vs. Ensembl Fly
Match: Clc (gene:FBgn0024814 transcript:FBtr0332771)

HSP 1 Score: 57.7658 bits (138), Expect = 8.269e-10
Identity = 51/148 (34.46%), Postives = 75/148 (50.68%), Query Frame = 3 
Query:  165 IDIDSNSYYKSASPP--KVEPEKIKKWREEFKSRLEIKDKNEQQKIEDLEMTANKELHDWCLRYREQLRITVKNNREDNARLVMEQTKINETASKNDYHVKETKIWESICKMCNFKPXXXXXXXXXPQNVKEATRMRELLMSLRHQPL 602
            I  +SN     + PP  + EPEKI+KWREE K RLE KD  E++K E+L   + KEL DW  +  E +  T   +R  NA          + A+  +  ++    WE I K+C+F P  N A        K+ +RMR + + L+  P+
Sbjct:   83 IGGESNEPVGISGPPPSREEPEKIRKWREEQKQRLEEKDIEEERKKEELRQQSKKELDDWLRQIGESISKTKLASR--NAE--------KQAATLENGTIEPGTEWERIAKLCDFNPKVNKAG-------KDVSRMRSIYLHLKQNPI 213
[Close]
BLAST of Clathrin light chain vs. Ensembl Fly
Match: Clc (gene:FBgn0024814 transcript:FBtr0300813)

HSP 1 Score: 57.7658 bits (138), Expect = 8.269e-10
Identity = 51/148 (34.46%), Postives = 75/148 (50.68%), Query Frame = 3 
Query:  165 IDIDSNSYYKSASPP--KVEPEKIKKWREEFKSRLEIKDKNEQQKIEDLEMTANKELHDWCLRYREQLRITVKNNREDNARLVMEQTKINETASKNDYHVKETKIWESICKMCNFKPXXXXXXXXXPQNVKEATRMRELLMSLRHQPL 602
            I  +SN     + PP  + EPEKI+KWREE K RLE KD  E++K E+L   + KEL DW  +  E +  T   +R  NA          + A+  +  ++    WE I K+C+F P  N A        K+ +RMR + + L+  P+
Sbjct:   83 IGGESNEPVGISGPPPSREEPEKIRKWREEQKQRLEEKDIEEERKKEELRQQSKKELDDWLRQIGESISKTKLASR--NAE--------KQAATLENGTIEPGTEWERIAKLCDFNPKVNKAG-------KDVSRMRSIYLHLKQNPI 213
[Close]
BLAST of Clathrin light chain vs. Ensembl Fly
Match: Clc (gene:FBgn0024814 transcript:FBtr0301126)

HSP 1 Score: 57.7658 bits (138), Expect = 8.269e-10
Identity = 51/148 (34.46%), Postives = 75/148 (50.68%), Query Frame = 3 
Query:  165 IDIDSNSYYKSASPP--KVEPEKIKKWREEFKSRLEIKDKNEQQKIEDLEMTANKELHDWCLRYREQLRITVKNNREDNARLVMEQTKINETASKNDYHVKETKIWESICKMCNFKPXXXXXXXXXPQNVKEATRMRELLMSLRHQPL 602
            I  +SN     + PP  + EPEKI+KWREE K RLE KD  E++K E+L   + KEL DW  +  E +  T   +R  NA          + A+  +  ++    WE I K+C+F P  N A        K+ +RMR + + L+  P+
Sbjct:   83 IGGESNEPVGISGPPPSREEPEKIRKWREEQKQRLEEKDIEEERKKEELRQQSKKELDDWLRQIGESISKTKLASR--NAE--------KQAATLENGTIEPGTEWERIAKLCDFNPKVNKAG-------KDVSRMRSIYLHLKQNPI 213
[Close]
BLAST of Clathrin light chain vs. Ensembl Fly
Match: Clc (gene:FBgn0024814 transcript:FBtr0074830)

HSP 1 Score: 57.7658 bits (138), Expect = 8.269e-10
Identity = 51/148 (34.46%), Postives = 75/148 (50.68%), Query Frame = 3 
Query:  165 IDIDSNSYYKSASPP--KVEPEKIKKWREEFKSRLEIKDKNEQQKIEDLEMTANKELHDWCLRYREQLRITVKNNREDNARLVMEQTKINETASKNDYHVKETKIWESICKMCNFKPXXXXXXXXXPQNVKEATRMRELLMSLRHQPL 602
            I  +SN     + PP  + EPEKI+KWREE K RLE KD  E++K E+L   + KEL DW  +  E +  T   +R  NA          + A+  +  ++    WE I K+C+F P  N A        K+ +RMR + + L+  P+
Sbjct:   83 IGGESNEPVGISGPPPSREEPEKIRKWREEQKQRLEEKDIEEERKKEELRQQSKKELDDWLRQIGESISKTKLASR--NAE--------KQAATLENGTIEPGTEWERIAKLCDFNPKVNKAG-------KDVSRMRSIYLHLKQNPI 213
[Close]
BLAST of Clathrin light chain vs. Ensembl Zebrafish
Match: clta (clathrin, light chain A [Source:ZFIN;Acc:ZDB-GENE-040426-1986])

HSP 1 Score: 68.5514 bits (166), Expect = 1.177e-13
Identity = 45/133 (33.83%), Postives = 71/133 (53.38%), Query Frame = 3 
Query:  210 KVEPEKIKKWREEFKSRLEIKDKNEQQKIEDLEMTANKELHDWCLRYREQLRITVKNNREDNARLVMEQTKINETASKNDYHVKETKIWESICKMCNFKPXXXXXXXXXPQNVKEATRMRELLMSLRHQPLVR 608
            + EPE ++KWREE + RLE  D N +++  + +  A  EL +W  R  EQL  T  NNR     +V E   ++E +   +        WE + ++C+F P S+       +  K+ +RMR +L+SL+  PLVR
Sbjct:   91 QAEPESLRKWREEQRDRLEELDANSRKQEAEWKEKAKLELEEWHTRQNEQLEKTKVNNRAAEEAMVSE---LDENSPGTE--------WERVARLCDFNPKSS-------KQAKDVSRMRSVLISLKQAPLVR 205
[Close]
BLAST of Clathrin light chain vs. Ensembl Zebrafish
Match: clta (clathrin, light chain A [Source:ZFIN;Acc:ZDB-GENE-040426-1986])

HSP 1 Score: 68.5514 bits (166), Expect = 1.177e-13
Identity = 45/133 (33.83%), Postives = 71/133 (53.38%), Query Frame = 3 
Query:  210 KVEPEKIKKWREEFKSRLEIKDKNEQQKIEDLEMTANKELHDWCLRYREQLRITVKNNREDNARLVMEQTKINETASKNDYHVKETKIWESICKMCNFKPXXXXXXXXXPQNVKEATRMRELLMSLRHQPLVR 608
            + EPE ++KWREE + RLE  D N +++  + +  A  EL +W  R  EQL  T  NNR     +V E   ++E +   +        WE + ++C+F P S+       +  K+ +RMR +L+SL+  PLVR
Sbjct:   91 QAEPESLRKWREEQRDRLEELDANSRKQEAEWKEKAKLELEEWHTRQNEQLEKTKVNNRAAEEAMVSE---LDENSPGTE--------WERVARLCDFNPKSS-------KQAKDVSRMRSVLISLKQAPLVR 205
[Close]
BLAST of Clathrin light chain vs. Ensembl Zebrafish
Match: clta (clathrin, light chain A [Source:ZFIN;Acc:ZDB-GENE-040426-1986])

HSP 1 Score: 68.5514 bits (166), Expect = 1.700e-13
Identity = 51/152 (33.55%), Postives = 76/152 (50.00%), Query Frame = 3 
Query:  210 KVEPEKIKKWREEFKSRLEIKDKNEQQKIEDLEMTANKELHDWCLRYREQLRITVKNNR---ED-----NARLVMEQTKINETASKNDYHVKETKI-----------WESICKMCNFKPXXXXXXXXXPQNVKEATRMRELLMSLRHQPLVR 608
            + EPE ++KWREE + RLE  D N +++  + +  A  EL +W  R  EQL  T  NNR   ED      A L+   T IN    + D   +E  +           WE + ++C+F P S+       +  K+ +RMR +L+SL+  PLVR
Sbjct:   91 QAEPESLRKWREEQRDRLEELDANSRKQEAEWKEKAKLELEEWHTRQNEQLEKTKVNNRVLDEDFYKQPFADLIGYVTHINHPCYRLDQAAEEAMVSELDENSPGTEWERVARLCDFNPKSS-------KQAKDVSRMRSVLISLKQAPLVR 235
[Close]
BLAST of Clathrin light chain vs. Ensembl Zebrafish
Match: clta (clathrin, light chain A [Source:ZFIN;Acc:ZDB-GENE-040426-1986])

HSP 1 Score: 68.5514 bits (166), Expect = 1.700e-13
Identity = 51/152 (33.55%), Postives = 76/152 (50.00%), Query Frame = 3 
Query:  210 KVEPEKIKKWREEFKSRLEIKDKNEQQKIEDLEMTANKELHDWCLRYREQLRITVKNNR---ED-----NARLVMEQTKINETASKNDYHVKETKI-----------WESICKMCNFKPXXXXXXXXXPQNVKEATRMRELLMSLRHQPLVR 608
            + EPE ++KWREE + RLE  D N +++  + +  A  EL +W  R  EQL  T  NNR   ED      A L+   T IN    + D   +E  +           WE + ++C+F P S+       +  K+ +RMR +L+SL+  PLVR
Sbjct:   91 QAEPESLRKWREEQRDRLEELDANSRKQEAEWKEKAKLELEEWHTRQNEQLEKTKVNNRVLDEDFYKQPFADLIGYVTHINHPCYRLDQAAEEAMVSELDENSPGTEWERVARLCDFNPKSS-------KQAKDVSRMRSVLISLKQAPLVR 235
[Close]
BLAST of Clathrin light chain vs. Ensembl Zebrafish
Match: clta (clathrin, light chain A [Source:ZFIN;Acc:ZDB-GENE-040426-1986])

HSP 1 Score: 65.855 bits (159), Expect = 1.737e-12
Identity = 49/141 (34.75%), Postives = 74/141 (52.48%), Query Frame = 3 
Query:  210 KVEPEKIKKWREEFKSRLEIKDKNEQQKIEDLEMTANKELHDWCLRYREQLRITVKNNR---ED-----NARLVMEQTKINETASKNDYHVKETKIWESICKMCNFKPXXXXXXXXXPQNVKEATRMRELLMSLRHQPLVR 608
            + EPE ++KWREE + RLE  D N +++  + +  A  EL +W  R  EQL  T  NNR   ED      A L+          S+ D +   T+ WE + ++C+F P S+       +  K+ +RMR +L+SL+  PLVR
Sbjct:   91 QAEPESLRKWREEQRDRLEELDANSRKQEAEWKEKAKLELEEWHTRQNEQLEKTKVNNRVLDEDFYKQPFADLIGYVAAEEAMVSELDENSPGTE-WERVARLCDFNPKSS-------KQAKDVSRMRSVLISLKQAPLVR 223
[Close]
BLAST of Clathrin light chain vs. Ensembl Xenopus
Match: dbp (D site of albumin promoter (albumin D-box) binding protein [Source:Xenbase;Acc:XB-GENE-5995286])

HSP 1 Score: 76.2554 bits (186), Expect = 2.719e-16
Identity = 49/152 (32.24%), Postives = 77/152 (50.66%), Query Frame = 3 
Query:  150 FSENTIDIDSNSYYKSASPPKVEPEKIKKWREEFKSRLEIKDKNEQQKIEDLEMTANKELHDWCLRYREQLRITVKNNREDNARLVMEQTKINETASKNDYHVKETKIWESICKMCNFKPXXXXXXXXXPQNVKEATRMRELLMSLRHQPLV 605
            + E     D  +    A   + EPE I+KWREE +SRLE+ D N +++  + +  A KEL +W  R  E L+ T  NNR      V   + + ET+   +        WE + ++C+F P S+       +  K+ +RMR +L+SL+  PLV
Sbjct:   69 YQETNGPTDGYAAISHADRLQAEPESIRKWREEQRSRLEMLDANSKKQETEWKDKAGKELEEWYARQDELLQKTKANNRAAEEAFV---SDVEETSPGTE--------WERVARLCDFNPKSS-------KQAKDVSRMRSVLISLKQAPLV 202
[Close]
BLAST of Clathrin light chain vs. Ensembl Xenopus
Match: dbp (D site of albumin promoter (albumin D-box) binding protein [Source:Xenbase;Acc:XB-GENE-5995286])

HSP 1 Score: 74.3294 bits (181), Expect = 1.511e-15
Identity = 52/155 (33.55%), Postives = 80/155 (51.61%), Query Frame = 3 
Query:  150 FSENTIDIDSNSYYKSASPPKVEPEKIKKWREEFKSRLEIKDKNEQQKIEDLEMTANKELHDWCLRYREQLRITVKNNREDNARLVMEQTKINETASKNDYHVKETKI---WESICKMCNFKPXXXXXXXXXPQNVKEATRMRELLMSLRHQPLV 605
            + E     D  +    A   + EPE I+KWREE +SRLE+ D N +++  + +  A KEL +W  R  E L+ T  NNR +         +  E A  +D  V+ET     WE + ++C+F P S+       +  K+ +RMR +L+SL+  PLV
Sbjct:   69 YQETNGPTDGYAAISHADRLQAEPESIRKWREEQRSRLEMLDANSKKQETEWKDKAGKELEEWYARQDELLQKTKANNRTNINHPCYSLEQAAEEAFVSD--VEETSPGTEWERVARLCDFNPKSS-------KQAKDVSRMRSVLISLKQAPLV 214
[Close]
BLAST of Clathrin light chain vs. Ensembl Xenopus
Match: dbp (D site of albumin promoter (albumin D-box) binding protein [Source:Xenbase;Acc:XB-GENE-5995286])

HSP 1 Score: 72.7886 bits (177), Expect = 6.362e-15
Identity = 48/139 (34.53%), Postives = 76/139 (54.68%), Query Frame = 3 
Query:  210 KVEPEKIKKWREEFKSRLEIKDKNEQQKIEDLEMTANKELHDWCLRYREQLRITVKNNREDNARLVMEQTK--INETASKNDY--HVKETKI---WESICKMCNFKPXXXXXXXXXPQNVKEATRMRELLMSLRHQPLV 605
            + EPE I+KWREE +SRLE+ D N +++  + +  A KEL +W  R  E L+ T  NNR  +     +     I   A++  +   V+ET     WE + ++C+F P S+       +  K+ +RMR +L+SL+  PLV
Sbjct:   89 QAEPESIRKWREEQRSRLEMLDANSKKQETEWKDKAGKELEEWYARQDELLQKTKANNRVADEAFYKQPFADVIGYVAAEEAFVSDVEETSPGTEWERVARLCDFNPKSS-------KQAKDVSRMRSVLISLKQAPLV 220
[Close]
BLAST of Clathrin light chain vs. Ensembl Xenopus
Match: dbp (D site of albumin promoter (albumin D-box) binding protein [Source:Xenbase;Acc:XB-GENE-5995286])

HSP 1 Score: 72.7886 bits (177), Expect = 8.649e-15
Identity = 55/171 (32.16%), Postives = 86/171 (50.29%), Query Frame = 3 
Query:  150 FSENTIDIDSNSYYKSASPPKVEPEKIKKWREEFKSRLEIKDKNEQQKIEDLEMTANKELHDWCLRYREQLRITVKNNREDN--------ARLVMEQTKIN------ETASKNDY--HVKETKI---WESICKMCNFKPXXXXXXXXXPQNVKEATRMRELLMSLRHQPLV 605
            + E     D  +    A   + EPE I+KWREE +SRLE+ D N +++  + +  A KEL +W  R  E L+ T  NNR  +        A ++   T IN      E A++  +   V+ET     WE + ++C+F P S+       +  K+ +RMR +L+SL+  PLV
Sbjct:   69 YQETNGPTDGYAAISHADRLQAEPESIRKWREEQRSRLEMLDANSKKQETEWKDKAGKELEEWYARQDELLQKTKANNRVADEAFYKQPFADVIGYVTNINHPCYSLEQAAEEAFVSDVEETSPGTEWERVARLCDFNPKSS-------KQAKDVSRMRSVLISLKQAPLV 232
[Close]
BLAST of Clathrin light chain vs. Ensembl Xenopus
Match: cltb (clathrin, light chain B [Source:NCBI gene;Acc:496489])

HSP 1 Score: 61.2326 bits (147), Expect = 8.013e-11
Identity = 44/146 (30.14%), Postives = 74/146 (50.68%), Query Frame = 3 
Query:  177 SNSYYKSASPPKV--EPEKIKKWREEFKSRLEIKDKNEQQKIEDLEMTANKELHDWCLRYREQLRITVKNNREDNARLVMEQTKINETASKNDYHVKETKIWESICKMCNFKPXXXXXXXXXPQNVKEATRMRELLMSLRHQPLVR 608
            S+ Y   A   ++  EPE ++KWREE K+RLE  D   +   ++    A K+L +W  R  EQ+     +NR  +  +  + TK  ET ++          WE + ++C+F P S+       +  K+ +R+R +L+SL+  PL R
Sbjct:   78 SDGYAAIAQADRLTQEPESLRKWREEQKTRLEELDAASKVTEQEWREKAKKDLDEWYQRQSEQIEKNKVSNRASDEAMASD-TKEEETGTE----------WERVARLCDFNPKSS-------KQSKDVSRLRSVLISLKQTPLSR 205
[Close]
BLAST of Clathrin light chain vs. Ensembl Mouse
Match: Clta (clathrin, light polypeptide (Lca) [Source:MGI Symbol;Acc:MGI:894297])

HSP 1 Score: 72.7886 bits (177), Expect = 5.221e-15
Identity = 46/130 (35.38%), Postives = 69/130 (53.08%), Query Frame = 3 
Query:  216 EPEKIKKWREEFKSRLEIKDKNEQQKIEDLEMTANKELHDWCLRYREQLRITVKNNREDNARLVMEQTKINETASKNDYHVKETKIWESICKMCNFKPXXXXXXXXXPQNVKEATRMRELLMSLRHQPLV 605
            EPE I+KWREE   RLE  D N +++  + +  A KEL +W  R  EQL+ T  NNR      V     I+E++   +        WE + ++C+F P S+       +  K+ +RMR +L+SL+  PLV
Sbjct:  104 EPESIRKWREEQTERLEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNRAAEEAFV---NDIDESSPGTE--------WERVARLCDFNPKSS-------KQAKDVSRMRSVLISLKQAPLV 215
[Close]
BLAST of Clathrin light chain vs. Ensembl Mouse
Match: Clta (clathrin, light polypeptide (Lca) [Source:MGI Symbol;Acc:MGI:894297])

HSP 1 Score: 72.7886 bits (177), Expect = 5.506e-15
Identity = 46/130 (35.38%), Postives = 69/130 (53.08%), Query Frame = 3 
Query:  216 EPEKIKKWREEFKSRLEIKDKNEQQKIEDLEMTANKELHDWCLRYREQLRITVKNNREDNARLVMEQTKINETASKNDYHVKETKIWESICKMCNFKPXXXXXXXXXPQNVKEATRMRELLMSLRHQPLV 605
            EPE I+KWREE   RLE  D N +++  + +  A KEL +W  R  EQL+ T  NNR      V     I+E++   +        WE + ++C+F P S+       +  K+ +RMR +L+SL+  PLV
Sbjct:  106 EPESIRKWREEQTERLEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNRAAEEAFV---NDIDESSPGTE--------WERVARLCDFNPKSS-------KQAKDVSRMRSVLISLKQAPLV 217
[Close]
BLAST of Clathrin light chain vs. Ensembl Mouse
Match: Clta (clathrin, light polypeptide (Lca) [Source:MGI Symbol;Acc:MGI:894297])

HSP 1 Score: 72.7886 bits (177), Expect = 5.506e-15
Identity = 46/130 (35.38%), Postives = 69/130 (53.08%), Query Frame = 3 
Query:  216 EPEKIKKWREEFKSRLEIKDKNEQQKIEDLEMTANKELHDWCLRYREQLRITVKNNREDNARLVMEQTKINETASKNDYHVKETKIWESICKMCNFKPXXXXXXXXXPQNVKEATRMRELLMSLRHQPLV 605
            EPE I+KWREE   RLE  D N +++  + +  A KEL +W  R  EQL+ T  NNR      V     I+E++   +        WE + ++C+F P S+       +  K+ +RMR +L+SL+  PLV
Sbjct:  106 EPESIRKWREEQTERLEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNRAAEEAFV---NDIDESSPGTE--------WERVARLCDFNPKSS-------KQAKDVSRMRSVLISLKQAPLV 217
[Close]
BLAST of Clathrin light chain vs. Ensembl Mouse
Match: Clta (clathrin, light polypeptide (Lca) [Source:MGI Symbol;Acc:MGI:894297])

HSP 1 Score: 69.707 bits (169), Expect = 7.551e-14
Identity = 46/131 (35.11%), Postives = 67/131 (51.15%), Query Frame = 3 
Query:  216 EPEKIKKWREEFKSRLEIKDKNEQQKIEDLEMTANKELHDWCLRYREQLRITVKNNREDNARLVMEQTKINETASKNDYHVKETKI-WESICKMCNFKPXXXXXXXXXPQNVKEATRMRELLMSLRHQPLV 605
            EPE I+KWREE   RLE  D N +++  + +  A KEL +W  R  EQL+ T  NN  +         +  E A  ND         WE + ++C+F P S+       +  K+ +RMR +L+SL+  PLV
Sbjct:  106 EPESIRKWREEQTERLEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNSTNINHPCYSLEQAAEEAFVNDIDESSPGTEWERVARLCDFNPKSS-------KQAKDVSRMRSVLISLKQAPLV 229
[Close]
BLAST of Clathrin light chain vs. Ensembl Mouse
Match: Clta (clathrin, light polypeptide (Lca) [Source:MGI Symbol;Acc:MGI:894297])

HSP 1 Score: 69.707 bits (169), Expect = 8.281e-14
Identity = 52/149 (34.90%), Postives = 73/149 (48.99%), Query Frame = 3 
Query:  216 EPEKIKKWREEFKSRLEIKDKNEQQKIEDLEMTANKELHDWCLRYREQLRITVKNNREDN--------ARLVMEQTKIN----------ETASKNDYHVKETKI-WESICKMCNFKPXXXXXXXXXPQNVKEATRMRELLMSLRHQPLV 605
            EPE I+KWREE   RLE  D N +++  + +  A KEL +W  R  EQL+ T  NNR  +        A L+   T IN          E A  ND         WE + ++C+F P S+       +  K+ +RMR +L+SL+  PLV
Sbjct:  106 EPESIRKWREEQTERLEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNRVADEAFYKQPFADLIGYVTNINHPCYSLEQAAEEAFVNDIDESSPGTEWERVARLCDFNPKSS-------KQAKDVSRMRSVLISLKQAPLV 247
[Close]
BLAST of Clathrin light chain vs. UniProt/SwissProt
Match: sp|P04973|CLCA_BOVIN (Clathrin light chain A OS=Bos taurus OX=9913 GN=CLTA PE=1 SV=1)

HSP 1 Score: 68.9366 bits (167), Expect = 1.079e-12
Identity = 51/149 (34.23%), Postives = 73/149 (48.99%), Query Frame = 3 
Query:  216 EPEKIKKWREEFKSRLEIKDKNEQQKIEDLEMTANKELHDWCLRYREQLRITVKNNREDN--------ARLVMEQTKIN----------ETASKNDYHVKETKI-WESICKMCNFKPXXXXXXXXXPQNVKEATRMRELLMSLRHQPLV 605
            EPE I+KWREE   RLE  D N +++  + +  A KEL +W  R  EQL+ T  NNR  +        A ++   T IN          E A  ND         WE + ++C+F P S+       +  K+ +RMR +L+SL+  PLV
Sbjct:  101 EPESIRKWREEQTERLEALDANSRKQEAEWKEKAIKELDEWYARQDEQLQKTKANNRVADEAFYKQPFADVIGYVTNINHPCYSLEQAAEEAFVNDIEESSPGTEWERVARLCDFNPKSS-------KQAKDVSRMRSVLISLKQAPLV 242
[Close]
BLAST of Clathrin light chain vs. UniProt/SwissProt
Match: sp|O08585|CLCA_MOUSE (Clathrin light chain A OS=Mus musculus OX=10090 GN=Clta PE=1 SV=2)

HSP 1 Score: 68.5514 bits (166), Expect = 1.630e-12
Identity = 47/142 (33.10%), Postives = 72/142 (50.70%), Query Frame = 3 
Query:  216 EPEKIKKWREEFKSRLEIKDKNEQQKIEDLEMTANKELHDWCLRYREQLRITVKNNREDN------------ARLVMEQTKINETASKNDYHVKETKIWESICKMCNFKPXXXXXXXXXPQNVKEATRMRELLMSLRHQPLV 605
            EPE I+KWREE   RLE  D N +++  + +  A KEL +W  R  EQL+ T  NNR  +              +  E+  +N+     D     T+ WE + ++C+F P S+       +  K+ +RMR +L+SL+  PLV
Sbjct:  105 EPESIRKWREEQTERLEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNRVADEAFYKQPFADLIGYVAAEEAFVNDI----DESSPGTE-WERVARLCDFNPKSS-------KQAKDVSRMRSVLISLKQAPLV 234
[Close]
BLAST of Clathrin light chain vs. UniProt/SwissProt
Match: sp|P09496|CLCA_HUMAN (Clathrin light chain A OS=Homo sapiens OX=9606 GN=CLTA PE=1 SV=1)

HSP 1 Score: 68.1662 bits (165), Expect = 2.210e-12
Identity = 51/149 (34.23%), Postives = 73/149 (48.99%), Query Frame = 3 
Query:  216 EPEKIKKWREEFKSRLEIKDKNEQQKIEDLEMTANKELHDWCLRYREQLRITVKNNREDN--------ARLVMEQTKIN----------ETASKNDYHVKETKI-WESICKMCNFKPXXXXXXXXXPQNVKEATRMRELLMSLRHQPLV 605
            EPE I+KWREE   RLE  D N +++  + +  A KEL +W  R  EQL+ T  NNR  +        A ++   T IN          E A  ND         WE + ++C+F P S+       +  K+ +RMR +L+SL+  PLV
Sbjct:  106 EPESIRKWREEQMERLEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNRVADEAFYKQPFADVIGYVTNINHPCYSLEQAAEEAFVNDIDESSPGTEWERVARLCDFNPKSS-------KQAKDVSRMRSVLISLKQAPLV 247
[Close]
BLAST of Clathrin light chain vs. UniProt/SwissProt
Match: sp|P08081|CLCA_RAT (Clathrin light chain A OS=Rattus norvegicus OX=10116 GN=Clta PE=1 SV=1)

HSP 1 Score: 67.0106 bits (162), Expect = 6.425e-12
Identity = 50/149 (33.56%), Postives = 73/149 (48.99%), Query Frame = 3 
Query:  216 EPEKIKKWREEFKSRLEIKDKNEQQKIEDLEMTANKELHDWCLRYREQLRITVKNNREDN--------ARLVMEQTKIN----------ETASKNDYHVKETKI-WESICKMCNFKPXXXXXXXXXPQNVKEATRMRELLMSLRHQPLV 605
            EPE I+KWREE   RLE  D N +++  + +  A KEL +W  R  EQL+ T  +NR  +        A ++   T IN          E A  ND         WE + ++C+F P S+       +  K+ +RMR +L+SL+  PLV
Sbjct:  106 EPESIRKWREEQTERLEALDANSRKQEAEWKEKAVKELEEWYARQDEQLQKTKASNRVADEAFYKQPFADVIGYVTNINHPCYSLEQAAEEAFVNDIDESSPGTEWERVARLCDFNPKSS-------KQAKDVSRMRSVLISLKQAPLV 247
[Close]
BLAST of Clathrin light chain vs. UniProt/SwissProt
Match: sp|P09497|CLCB_HUMAN (Clathrin light chain B OS=Homo sapiens OX=9606 GN=CLTB PE=1 SV=1)

HSP 1 Score: 61.6178 bits (148), Expect = 4.511e-10
Identity = 45/138 (32.61%), Postives = 68/138 (49.28%), Query Frame = 3 
Query:  216 EPEKIKKWREEFKSRLEIKDKNEQQKIEDLEMTANKELHDWCLRYREQLRITVKNNR-EDNARLVMEQTKINETASKNDYHVKETK------IWESICKMCNFKPXXXXXXXXXPQNVKEATRMRELLMSLRHQPLVR 608
            EPE I+KWREE + RL+  D   +   ++    A K+L +W  R  EQ+     NNR  D A        I    +  +  VKE+K       WE + ++C+F P S+       +  K+ +R+R +LMSL+  PL R
Sbjct:   99 EPESIRKWREEQRKRLQELDAASKVTEQEWREKAKKDLEEWNQRQSEQVEKNKINNRIADKAFYQQPDADIIGYVASEEAFVKESKEETPGTEWEKVAQLCDFNPKSS-------KQCKDVSRLRSVLMSLKQTPLSR 229
[Close]
BLAST of Clathrin light chain vs. TrEMBL
Match: A0A2T7PFE9 (Clathrin light chain OS=Pomacea canaliculata OX=400727 GN=C0Q70_07552 PE=3 SV=1)

HSP 1 Score: 86.2705 bits (212), Expect = 9.591e-17
Identity = 58/166 (34.94%), Postives = 86/166 (51.81%), Query Frame = 3 
Query:  138 FFKDFSENTIDIDS------NSYYKSASPP---KVEPEKIKKWREEFKSRLEIKDKNEQQKIEDLEMTANKELHDWCLRYREQLRITVKNNREDNARLVMEQTKINETASKNDYHVKETKIWESICKMCNFKPXXXXXXXXXPQNVKEATRMRELLMSLRHQPLVR 608
            F  DF    +D  +      +  Y S S     + EPEKI+ WREE K+RL+ KD+ E++  E+    A KEL DW  ++ EQL  T +NNR +N R + E+          D  V   + WE I ++C F P ++       +N K+ +RMR +L+ L+  PLVR
Sbjct:   58 FVDDFGGGGVDFSAEQVNGPSDIYASISQQDSFRAEPEKIRIWREEQKARLQRKDEAEEETKEEWREKAKKELDDWYKKHAEQLEKTRENNRSENERFLKERAAEEAFIKDRDEKVP-GQAWEKITRLCEFNPKNS-------KNTKDVSRMRSILLQLKQTPLVR 215
[Close]
BLAST of Clathrin light chain vs. TrEMBL
Match: G7YLL9 (Clathrin light chain OS=Clonorchis sinensis OX=79923 GN=Clta PE=3 SV=1)

HSP 1 Score: 82.8037 bits (203), Expect = 4.391e-16
Identity = 50/140 (35.71%), Postives = 80/140 (57.14%), Query Frame = 3 
Query:  216 EPEKIKKWREEFKSRLEIKDKNEQQKIEDLEMTANKELHDWCLRYREQLRITVKNNREDNARLVMEQT-KINETASKNDYHVKETKIWESICKMCNF-KPXXXXXXXXXPQN--------VKEATRMRELLMSLRHQPLV 605
            +PE IKKW  EF+ R+ IKD NEQ+K+  LE   +K+LH+W ++YRE L   +K++R     L  EQT     ++S +     +  +W+ +C++CNF  P   + +++ P +         K+  RMR LL+ L+ QP V
Sbjct:    7 QPECIKKWAIEFEERIRIKDGNEQKKLSLLEEQGSKDLHNWAMQYRESLSRAIKDSRAHEKELRAEQTAAAEASSSISGADASQAVLWDRVCQLCNFVSPNPEDGSSTPPVSRHPGTKDPSKDLNRMRILLLQLKQQPPV 146
[Close]
BLAST of Clathrin light chain vs. TrEMBL
Match: A0A5J4N606 (Clathrin light chain OS=Paragonimus westermani OX=34504 GN=DEA37_0004954 PE=3 SV=1)

HSP 1 Score: 83.1889 bits (204), Expect = 7.295e-16
Identity = 51/158 (32.28%), Postives = 84/158 (53.16%), Query Frame = 3 
Query:  147 DFSENTIDIDSNSYYKSASPPKVEPEKIKKWREEFKSRLEIKDKNEQQKIEDLEMTANKELHDWCLRYREQLRITVKNNREDNARLVMEQTKI-NETASKNDYHVKETKIWESICKMCNFKPXXXXXXXXXPQNV------KEATRMRELLMSLRHQP 599
            DFSE   +++       +S  + +PE IK W  EF+ R+ +KD+ E  K+  LE    K+LHDW  +YRE L   +K++R  +  L +EQ  +   +A+  D       +WE +C +CNF  A+ +   S+ +++      K+  RMR LL+ L+  P
Sbjct:   23 DFSEEISELNDVCDSTMSSNTQSQPECIKAWCLEFEERIRLKDEAESAKLTVLEEQGLKDLHDWANQYRESLSRAIKSSRAHDKDLRVEQNSLATASATLCDADASHPALWERVCHLCNFVTAAADDTGSAAKDLCTKDSSKDLHRMRTLLLQLKQNP 180
[Close]
BLAST of Clathrin light chain vs. TrEMBL
Match: V3ZM17 (Clathrin light chain OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_195870 PE=3 SV=1)

HSP 1 Score: 85.1149 bits (209), Expect = 7.648e-16
Identity = 55/133 (41.35%), Postives = 69/133 (51.88%), Query Frame = 3 
Query:  210 KVEPEKIKKWREEFKSRLEIKDKNEQQKIEDLEMTANKELHDWCLRYREQLRITVKNNREDNARLVMEQTKINETASKNDYHVKETKIWESICKMCNFKPXXXXXXXXXPQNVKEATRMRELLMSLRHQPLVR 608
            + EPEKIKKWREE K RLE KD  E +K  D +  A KEL DW   + EQL  T  NN      LV E+  I E       H      WE IC++C F P          ++ K+ TRMR +L+ L+  PLV+
Sbjct:  155 RSEPEKIKKWREEQKERLEKKDAEEVKKKADWQSVAKKELEDWYKHHSEQLTKTHSNN------LVAEKAFIKERDESVPGHE-----WEKICRLCEFNPKVV-------KSTKDVTRMRSILLQLKQTPLVK 269
[Close]
BLAST of Clathrin light chain vs. TrEMBL
Match: A0A074Z4D3 (Clathrin light chain OS=Opisthorchis viverrini OX=6198 GN=T265_09871 PE=3 SV=1)

HSP 1 Score: 83.5741 bits (205), Expect = 9.109e-16
Identity = 50/140 (35.71%), Postives = 79/140 (56.43%), Query Frame = 3 
Query:  216 EPEKIKKWREEFKSRLEIKDKNEQQKIEDLEMTANKELHDWCLRYREQLRITVKNNREDNARLVMEQT-KINETASKNDYHVKETKIWESICKMCNF-KPXXXXXXXXXPQN--------VKEATRMRELLMSLRHQPLV 605
            +PE IKKW  EF+ R+ IKD NEQ+K+  LE   +K+LH+W ++YRE L   +K++R     L  EQT     ++S +     +  +W+ +C++CNF  P   + + + P +         K+  RMR LL+ L+ QP V
Sbjct:   60 QPECIKKWAIEFEERIRIKDGNEQKKLSLLEEQGSKDLHNWAMQYRESLSRAIKDSRAHEKELRAEQTAAAEASSSISGADASQAVLWDRVCQLCNFVSPNPEDGSGTPPVSRHPGTKDPSKDLNRMRILLLQLKQQPPV 199
[Close]
BLAST of Clathrin light chain vs. Ensembl Cavefish
Match: clta (clathrin light chain A [Source:NCBI gene;Acc:103024617])

HSP 1 Score: 75.485 bits (184), Expect = 5.250e-16
Identity = 57/174 (32.76%), Postives = 83/174 (47.70%), Query Frame = 3 
Query:  144 KDFSENTIDIDSNSYYKSASPPKVEPEKIKKWREEFKSRLEIKDKNEQQKIEDLEMTANKELHDWCLRYREQLRITVKNNR---ED-----NARLVMEQTKINETASKNDYHVKETKI-----------WESICKMCNFKPXXXXXXXXXPQNVKEATRMRELLMSLRHQPLVR 608
             D  E+    D+ +   SA   + EPE ++KWREE   RLE  D N +Q+  + +  A  EL +W  R  EQL  T  NNR   ED      A L+   T IN    + D   +E  +           WE + ++C+F P S+       +  K+ +RMR +L+SL+  PLVR
Sbjct:   65 GDLHESNGPSDAYAAISSADRLQAEPESLRKWREEQSDRLEELDANSRQQETEWKEKAKVELEEWHARQDEQLAKTKVNNRVLDEDFYKQPFAHLIGYVTHINHPCYRLDQAAEEAMVSELDENNPGTEWERVARLCDFNPKSS-------KQAKDVSRMRSVLISLKQSPLVR 231
[Close]
BLAST of Clathrin light chain vs. Ensembl Cavefish
Match: clta (clathrin light chain A [Source:NCBI gene;Acc:103024617])

HSP 1 Score: 74.3294 bits (181), Expect = 8.416e-16
Identity = 51/155 (32.90%), Postives = 75/155 (48.39%), Query Frame = 3 
Query:  144 KDFSENTIDIDSNSYYKSASPPKVEPEKIKKWREEFKSRLEIKDKNEQQKIEDLEMTANKELHDWCLRYREQLRITVKNNREDNARLVMEQTKINETASKNDYHVKETKIWESICKMCNFKPXXXXXXXXXPQNVKEATRMRELLMSLRHQPLVR 608
             D  E+    D+ +   SA   + EPE ++KWREE   RLE  D N +Q+  + +  A  EL +W  R  EQL  T  NNR     +V E  + N               WE + ++C+F P S+       +  K+ +RMR +L+SL+  PLVR
Sbjct:   65 GDLHESNGPSDAYAAISSADRLQAEPESLRKWREEQSDRLEELDANSRQQETEWKEKAKVELEEWHARQDEQLAKTKVNNRAAEEAMVSELDENNPGTE-----------WERVARLCDFNPKSS-------KQAKDVSRMRSVLISLKQSPLVR 201
[Close]
BLAST of Clathrin light chain vs. Ensembl Cavefish
Match: clta (clathrin light chain A [Source:NCBI gene;Acc:103024617])

HSP 1 Score: 70.8626 bits (172), Expect = 1.752e-14
Identity = 55/163 (33.74%), Postives = 81/163 (49.69%), Query Frame = 3 
Query:  144 KDFSENTIDIDSNSYYKSASPPKVEPEKIKKWREEFKSRLEIKDKNEQQKIEDLEMTANKELHDWCLRYREQLRITVKNNR---ED-----NARLVMEQTKINETASKNDYHVKETKIWESICKMCNFKPXXXXXXXXXPQNVKEATRMRELLMSLRHQPLVR 608
             D  E+    D+ +   SA   + EPE ++KWREE   RLE  D N +Q+  + +  A  EL +W  R  EQL  T  NNR   ED      A L+          S+ D +   T+ WE + ++C+F P S+       +  K+ +RMR +L+SL+  PLVR
Sbjct:   65 GDLHESNGPSDAYAAISSADRLQAEPESLRKWREEQSDRLEELDANSRQQETEWKEKAKVELEEWHARQDEQLAKTKVNNRVLDEDFYKQPFAHLIGYVAAEEAMVSELDENNPGTE-WERVARLCDFNPKSS-------KQAKDVSRMRSVLISLKQSPLVR 219
[Close]
BLAST of Clathrin light chain vs. Ensembl Cavefish
Match: cltb (clathrin light chain B [Source:NCBI gene;Acc:103036957])

HSP 1 Score: 68.5514 bits (166), Expect = 1.380e-13
Identity = 46/138 (33.33%), Postives = 70/138 (50.72%), Query Frame = 3 
Query:  216 EPEKIKKWREEFKSRLEIKDKNEQQKIEDLEMTANKELHDWCLRYREQLRITVKNNR-EDNARLVMEQTKINETASKNDYHVKE------TKIWESICKMCNFKPXXXXXXXXXPQNVKEATRMRELLMSLRHQPLVR 608
            EPE ++KWREE K+RLE  D   +    + +  A KEL DW L  +EQ+     NNR  D A      + +    +  D  +KE         WE + ++C+F P ++       +  K+ +RMR +L+SL+  PLVR
Sbjct:   84 EPESLRKWREEQKTRLEELDSASKAAEVEWKEKAKKELVDWNLHQQEQMEKNKVNNRIADKAFYKQPNSDVIGFVASEDAFLKECDDDSPGSEWEKVARLCDFNPKTS-------RQTKDVSRMRSVLISLKQTPLVR 214
[Close]
BLAST of Clathrin light chain vs. Ensembl Nematostella
Match: EDO30793 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SZR4])

HSP 1 Score: 71.633 bits (174), Expect = 2.301e-15
Identity = 47/133 (35.34%), Postives = 73/133 (54.89%), Query Frame = 3 
Query:  210 KVEPEKIKKWREEFKSRLEIKDKNEQQKIEDLEMTANKELHDWCLRYREQLRITVKNNREDNARLVMEQTKINETASKNDYHVKETKIWESICKMCNFKPXXXXXXXXXPQNVKEATRMRELLMSLRHQPLVR 608
            ++E E ++KWREE  ++LE  D+ E+ +IE+    A+KEL+DW  R  EQL  T  +NR D    V E         ++D     T+ WE +C+ C+F P +        +N K+ +RMR + + L+  PLVR
Sbjct:   82 EIEHESVRKWREEKAAQLEKMDEEEKAEIEEWREQAHKELNDWYDRRNEQLGKTKNSNRADEESFVAE---------RDDTSTPGTE-WEKVCRACDFNPKAT-------KNTKDVSRMRSIFLQLKQNPLVR 197
[Close]
BLAST of Clathrin light chain vs. Ensembl Medaka
Match: clta (clathrin light chain A [Source:NCBI gene;Acc:111946915])

HSP 1 Score: 72.0182 bits (175), Expect = 6.744e-15
Identity = 47/145 (32.41%), Postives = 75/145 (51.72%), Query Frame = 3 
Query:  174 DSNSYYKSASPPKVEPEKIKKWREEFKSRLEIKDKNEQQKIEDLEMTANKELHDWCLRYREQLRITVKNNREDNARLVMEQTKINETASKNDYHVKETKIWESICKMCNFKPXXXXXXXXXPQNVKEATRMRELLMSLRHQPLVR 608
            D+ +   +A   + EPE ++KWREE + RLE+ D N +++  + +  A  EL +W  R  EQL  T  NNR        E+  I++    N         WE + ++C+F P S+       +  K+ +RMR +L+SL+  PLVR
Sbjct:   93 DAYAAISTADRLQAEPESLRKWREEQRERLEVLDANSRKQESEWKEKAKLELEEWHARQNEQLEKTKTNNR------AAEEAMISDLDENN-----PGTEWERVARLCDFNPKSS-------KQAKDVSRMRSVLISLKQSPLVR 219
[Close]
BLAST of Clathrin light chain vs. Ensembl Medaka
Match: cltb (clathrin light chain B [Source:NCBI gene;Acc:101175575])

HSP 1 Score: 71.633 bits (174), Expect = 8.470e-15
Identity = 52/153 (33.99%), Postives = 74/153 (48.37%), Query Frame = 3 
Query:  150 FSENTIDIDSNSYYKSASPPKVEPEKIKKWREEFKSRLEIKDKNEQQKIEDLEMTANKELHDWCLRYREQLRITVKNNREDNARLVMEQTKINETASKNDYHVKETKIWESICKMCNFKPXXXXXXXXXPQNVKEATRMRELLMSLRHQPLVR 608
            F E+    DS +        + EPE ++KWREE K+RLE  D   +    +    A KEL DW L   EQ+     NNR        E+  + ET S  D    E   WE + ++C+F P +N       +  K+ +RMR +L+SL+  PLVR
Sbjct:   69 FQESNGPTDSYAAIAQVDIQRQEPESLRKWREEQKARLEALDSASKAAEVEWREKAKKELEDWHLHQNEQMEKNKANNR------ASEEAFLAETDS--DAPGSE---WERVARLCDFNPKTN-------KQAKDVSRMRSVLISLKQTPLVR 203
[Close]
BLAST of Clathrin light chain vs. Ensembl Medaka
Match: cltb (clathrin light chain B [Source:NCBI gene;Acc:101175575])

HSP 1 Score: 71.633 bits (174), Expect = 8.832e-15
Identity = 52/153 (33.99%), Postives = 74/153 (48.37%), Query Frame = 3 
Query:  150 FSENTIDIDSNSYYKSASPPKVEPEKIKKWREEFKSRLEIKDKNEQQKIEDLEMTANKELHDWCLRYREQLRITVKNNREDNARLVMEQTKINETASKNDYHVKETKIWESICKMCNFKPXXXXXXXXXPQNVKEATRMRELLMSLRHQPLVR 608
            F E+    DS +        + EPE ++KWREE K+RLE  D   +    +    A KEL DW L   EQ+     NNR        E+  + ET S  D    E   WE + ++C+F P +N       +  K+ +RMR +L+SL+  PLVR
Sbjct:   72 FQESNGPTDSYAAIAQVDIQRQEPESLRKWREEQKARLEALDSASKAAEVEWREKAKKELEDWHLHQNEQMEKNKANNR------ASEEAFLAETDS--DAPGSE---WERVARLCDFNPKTN-------KQAKDVSRMRSVLISLKQTPLVR 206
[Close]
BLAST of Clathrin light chain vs. Ensembl Medaka
Match: cltb (clathrin light chain B [Source:NCBI gene;Acc:101175575])

HSP 1 Score: 70.0922 bits (170), Expect = 3.419e-14
Identity = 50/160 (31.25%), Postives = 75/160 (46.88%), Query Frame = 3 
Query:  150 FSENTIDIDSNSYYKSASPPKVEPEKIKKWREEFKSRLEIKDKNEQQKIEDLEMTANKELHDWCLRYREQLRITVKNNR-EDNARLVMEQTKINETASKNDYHVKETKI------WESICKMCNFKPXXXXXXXXXPQNVKEATRMRELLMSLRHQPLVR 608
            F E+    DS +        + EPE ++KWREE K+RLE  D   +    +    A KEL DW L   EQ+     NNR  D A      + +    +  +  + ET        WE + ++C+F P +N       +  K+ +RMR +L+SL+  PLVR
Sbjct:   69 FQESNGPTDSYAAIAQVDIQRQEPESLRKWREEQKARLEALDSASKAAEVEWREKAKKELEDWHLHQNEQMEKNKANNRIADKAFYKQPNSDVIGLVASEEAFLAETDSDAPGSEWERVARLCDFNPKTN-------KQAKDVSRMRSVLISLKQTPLVR 221
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BLAST of Clathrin light chain vs. Ensembl Medaka
Match: cltb (clathrin light chain B [Source:NCBI gene;Acc:101175575])

HSP 1 Score: 70.0922 bits (170), Expect = 3.480e-14
Identity = 50/155 (32.26%), Postives = 76/155 (49.03%), Query Frame = 3 
Query:  150 FSENTIDIDSNSYYKSASPPKVEPEKIKKWREEFKSRLEIKDKNEQQKIEDLEMTANKELHDWCLRYREQLRITVKNNREDNARLVMEQTKINETA--SKNDYHVKETKIWESICKMCNFKPXXXXXXXXXPQNVKEATRMRELLMSLRHQPLVR 608
            F E+    DS +        + EPE ++KWREE K+RLE  D   +    +    A KEL DW L   EQ+     NN     RL     + +E A  ++ D     ++ WE + ++C+F P +N       +  K+ +RMR +L+SL+  PLVR
Sbjct:   69 FQESNGPTDSYAAIAQVDIQRQEPESLRKWREEQKARLEALDSASKAAEVEWREKAKKELEDWHLHQNEQMEKNKANN-----RLCPSLARASEEAFLAETDSDAPGSE-WERVARLCDFNPKTN-------KQAKDVSRMRSVLISLKQTPLVR 210
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BLAST of Clathrin light chain vs. Planmine SMEST
Match: SMESG000019387.1 (SMESG000019387.1)

HSP 1 Score: 189.889 bits (481), Expect = 6.314e-62
Identity = 100/100 (100.00%), Postives = 100/100 (100.00%), Query Frame = 3 
Query:  309 MTANKELHDWCLRYREQLRITVKNNREDNARLVMEQTKINETASKNDYHVKETKIWESICKMCNFKPXXXXXXXXXPQNVKEATRMRELLMSLRHQPLVR 608
            MTANKELHDWCLRYREQLRITVKNNREDNARLVMEQTKINETASKNDYHVKETKIWESICKMCNFKPASNNANASSPQNVKEATRMRELLMSLRHQPLVR
Sbjct:    1 MTANKELHDWCLRYREQLRITVKNNREDNARLVMEQTKINETASKNDYHVKETKIWESICKMCNFKPASNNANASSPQNVKEATRMRELLMSLRHQPLVR 100
[Close]
BLAST of Clathrin light chain vs. Planmine SMEST
Match: SMESG000012224.1 (SMESG000012224.1)

HSP 1 Score: 78.1814 bits (191), Expect = 2.117e-17
Identity = 57/170 (33.53%), Postives = 87/170 (51.18%), Query Frame = 3 
Query:  147 DFSENTIDIDSNSYYKSA--------SPPKVEPEKIKKWREEFKSRLEIKDKNEQQKIEDLEMTANKELHDWCLRYREQLRITVKNNREDNARLVMEQTKINETASKNDYHVKETKIWESICKMCNF--------KPXXXXXXXXXPQNVKEATRMRELLMSLRHQPLVR 608
            DF  N I  +++SY +S         S P++EPEKI  WR EF+ R+  KD+ E++++ +LE  A KEL DW + + EQL    K NRE     V E+          D  +  ++ W+ +CKMC F        KP      +      K+ +RM+ +L+SL+  PL+R
Sbjct:   46 DFITNEIR-ENDSYGQSMNYNSKPEISMPRIEPEKILVWRREFEERIIKKDEEEKERMRNLERDAKKELEDWNVHHNEQLLNKRKLNRESQGVFVKER----------DQPIPGSE-WQRVCKMCEFNSRPAVSIKPVVPGGESLPVFTPKDTSRMKSILLSLKTDPLIR 203
The following BLAST results are available for this feature:
BLAST of Clathrin light chain vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CLTA1.075e-1435.38clathrin light chain A [Source:HGNC Symbol;Acc:HGN... [more]
CLTA1.441e-1335.11clathrin light chain A [Source:HGNC Symbol;Acc:HGN... [more]
CLTA1.441e-1335.11clathrin light chain A [Source:HGNC Symbol;Acc:HGN... [more]
CLTA4.602e-1334.23clathrin light chain A [Source:HGNC Symbol;Acc:HGN... [more]
CLTA4.602e-1334.23clathrin light chain A [Source:HGNC Symbol;Acc:HGN... [more]
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BLAST of Clathrin light chain vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Clathrin light chain vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 4
Match NameE-valueIdentityDescription
Clc8.269e-1034.46gene:FBgn0024814 transcript:FBtr0332771[more]
Clc8.269e-1034.46gene:FBgn0024814 transcript:FBtr0300813[more]
Clc8.269e-1034.46gene:FBgn0024814 transcript:FBtr0301126[more]
Clc8.269e-1034.46gene:FBgn0024814 transcript:FBtr0074830[more]
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BLAST of Clathrin light chain vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
clta1.177e-1333.83clathrin, light chain A [Source:ZFIN;Acc:ZDB-GENE-... [more]
clta1.177e-1333.83clathrin, light chain A [Source:ZFIN;Acc:ZDB-GENE-... [more]
clta1.700e-1333.55clathrin, light chain A [Source:ZFIN;Acc:ZDB-GENE-... [more]
clta1.700e-1333.55clathrin, light chain A [Source:ZFIN;Acc:ZDB-GENE-... [more]
clta1.737e-1234.75clathrin, light chain A [Source:ZFIN;Acc:ZDB-GENE-... [more]
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BLAST of Clathrin light chain vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dbp2.719e-1632.24D site of albumin promoter (albumin D-box) binding... [more]
dbp1.511e-1533.55D site of albumin promoter (albumin D-box) binding... [more]
dbp6.362e-1534.53D site of albumin promoter (albumin D-box) binding... [more]
dbp8.649e-1532.16D site of albumin promoter (albumin D-box) binding... [more]
cltb8.013e-1130.14clathrin, light chain B [Source:NCBI gene;Acc:4964... [more]
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BLAST of Clathrin light chain vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Clta5.221e-1535.38clathrin, light polypeptide (Lca) [Source:MGI Symb... [more]
Clta5.506e-1535.38clathrin, light polypeptide (Lca) [Source:MGI Symb... [more]
Clta5.506e-1535.38clathrin, light polypeptide (Lca) [Source:MGI Symb... [more]
Clta7.551e-1435.11clathrin, light polypeptide (Lca) [Source:MGI Symb... [more]
Clta8.281e-1434.90clathrin, light polypeptide (Lca) [Source:MGI Symb... [more]
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BLAST of Clathrin light chain vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P04973|CLCA_BOVIN1.079e-1234.23Clathrin light chain A OS=Bos taurus OX=9913 GN=CL... [more]
sp|O08585|CLCA_MOUSE1.630e-1233.10Clathrin light chain A OS=Mus musculus OX=10090 GN... [more]
sp|P09496|CLCA_HUMAN2.210e-1234.23Clathrin light chain A OS=Homo sapiens OX=9606 GN=... [more]
sp|P08081|CLCA_RAT6.425e-1233.56Clathrin light chain A OS=Rattus norvegicus OX=101... [more]
sp|P09497|CLCB_HUMAN4.511e-1032.61Clathrin light chain B OS=Homo sapiens OX=9606 GN=... [more]
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BLAST of Clathrin light chain vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A2T7PFE99.591e-1734.94Clathrin light chain OS=Pomacea canaliculata OX=40... [more]
G7YLL94.391e-1635.71Clathrin light chain OS=Clonorchis sinensis OX=799... [more]
A0A5J4N6067.295e-1632.28Clathrin light chain OS=Paragonimus westermani OX=... [more]
V3ZM177.648e-1641.35Clathrin light chain OS=Lottia gigantea OX=225164 ... [more]
A0A074Z4D39.109e-1635.71Clathrin light chain OS=Opisthorchis viverrini OX=... [more]
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BLAST of Clathrin light chain vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 4
Match NameE-valueIdentityDescription
clta5.250e-1632.76clathrin light chain A [Source:NCBI gene;Acc:10302... [more]
clta8.416e-1632.90clathrin light chain A [Source:NCBI gene;Acc:10302... [more]
clta1.752e-1433.74clathrin light chain A [Source:NCBI gene;Acc:10302... [more]
cltb1.380e-1333.33clathrin light chain B [Source:NCBI gene;Acc:10303... [more]
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BLAST of Clathrin light chain vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Clathrin light chain vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Clathrin light chain vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO307932.301e-1535.34Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Clathrin light chain vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
clta6.744e-1532.41clathrin light chain A [Source:NCBI gene;Acc:11194... [more]
cltb8.470e-1533.99clathrin light chain B [Source:NCBI gene;Acc:10117... [more]
cltb8.832e-1533.99clathrin light chain B [Source:NCBI gene;Acc:10117... [more]
cltb3.419e-1431.25clathrin light chain B [Source:NCBI gene;Acc:10117... [more]
cltb3.480e-1432.26clathrin light chain B [Source:NCBI gene;Acc:10117... [more]
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BLAST of Clathrin light chain vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 2
Match NameE-valueIdentityDescription
SMESG000019387.16.314e-62100.00SMESG000019387.1[more]
SMESG000012224.12.117e-1733.53SMESG000012224.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30019324 ID=SMED30019324|Name=Clathrin light chain|organism=Schmidtea mediterranea sexual|type=transcript|length=751bp
AGTAGCGATAATGGATGATCCAGCTAGTGAATTTTTTGAAAGAGAAAAAC
TTGAATTAGGAGACTTAAGTGATGAATTGAATTTCATAAACAATTCTGAT
AATAATGAAAGTAATTTTATTTGTTAACATTTTTTAATTCTTTAAAGATT
TCTCTGAAAATACCATTGATATTGATTCGAATTCCTACTATAAATCTGCA
AGCCCTCCTAAAGTTGAGCCTGAAAAAATAAAGAAGTGGCGTGAAGAATT
TAAAAGTCGCTTAGAAATCAAAGATAAAAATGAACAACAAAAAATAGAAG
ACTTGGAGATGACAGCCAATAAAGAATTGCATGATTGGTGTCTGAGATAT
CGTGAGCAACTGAGAATCACTGTGAAAAACAATAGGGAAGATAATGCTCG
ATTAGTTATGGAACAAACTAAAATTAATGAAACCGCCAGTAAAAATGATT
ATCATGTTAAAGAAACAAAAATTTGGGAAAGTATTTGTAAGATGTGTAAT
TTTAAACCTGCCTCAAATAATGCGAATGCATCAAGTCCGCAAAATGTAAA
GGAAGCGACTAGAATGAGAGAACTTTTGATGAGCCTTCGTCATCAACCTT
TAGTTCGCTAAGTCAATATTTTATTATTGGCGCGATCACTTAATATTTTC
AATTTATAATTCAAATAGAATGTAAACGCTTAGATTATTAATTTTTTAAG
TGTAGTTTATAATTAAATTGTATTTTATCAAATATAATTTAATTTTACTA
A
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protein sequence of SMED30019324-orf-1

>SMED30019324-orf-1 ID=SMED30019324-orf-1|Name=SMED30019324-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=101bp
MTANKELHDWCLRYREQLRITVKNNREDNARLVMEQTKINETASKNDYHV
KETKIWESICKMCNFKPASNNANASSPQNVKEATRMRELLMSLRHQPLVR
*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
PLANA:0000101muscle cell
PLANA:0000418head
Vocabulary: INTERPRO
TermDefinition
IPR000996Clathrin_L-chain
Vocabulary: cellular component
TermDefinition
GO:0030130clathrin coat of trans-Golgi network vesicle
GO:0030132clathrin coat of coated pit
GO:0005905clathrin-coated pit
GO:0016020membrane
GO:0030659cytoplasmic vesicle membrane
GO:0031410cytoplasmic vesicle
Vocabulary: biological process
TermDefinition
GO:0006886intracellular protein transport
GO:0016192vesicle-mediated transport
Vocabulary: molecular function
TermDefinition
GO:0005198structural molecule activity
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000996Clathrin light chainPFAMPF01086Clathrin_lg_chcoord: 2..98
e-value: 1.1E-12
score: 48.5