wdr-1

Query:   86 EINKLELINVIGFNGTILDGLHVHPDRQHIIYGLGCTVVIEDLNTKNQCFLQGHTNNVVCITVSNSGKYIASGQITHMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDGCVVIWSLTKMEPICGSPAQHKSAGITECLVYSNTNDDVFVTAGENTLRVWELDVENRKIRPTECSLGAIKRSIKCITISKDDSVFFCGTSSGDILGVNMKSCLLSCIGPEKETFSLGVLSIIRLINGDLIVGAGDGTICQVKVVEKKEGNKIMPKIVKTSNSCMLVGGVSSITLRGQGHQFYAGTEKSHIYRFSLGDFKSELINTAHYSAVNDIVYPNNCPKLFVTCSFQDVRVFHSDSQKELLRINIPNMTCYTCDIFKDGTAIITGWDDSKIRAFYPETGALMYTINDAHKKGVTAIAATSDCRKVVSGGGEGQVRVWRIEECKVSQANTIPHSHGNRKKSNVKSVVYVAHMETAMKEHANAVSCIRMNKDDTQCVSSSADGTCIIWCLIKYTRKQIMFANTLFRCVCWRPDECQIITSGTDRKIGYWEVYDGSLIRELEGSRSGSVNGMDITADGDIFVTGGDDKIVKVWKYNEGYVTHVGLGHSMPITRLRISPDRQLITTVSEDGAIYFWKFP 2017
            ++ +LEL  VIGFNG +  GL  HPD++H+IY LGCTV+I+ +NTK Q FLQGH NNV C+ +S SG+YIASGQ+T MG+KADI+LWDY  ++ ++  SLHK K+++LAFSPN+ YL SLGG DDG VV+WS+ K + ICGSPA   + G    +++S   D++F+TAG  T+RVWELD+ NRKI PTEC  G +KR +  I +  DDS F+ GT++GDIL +N ++ LL+ +GP K+ FSLGV +I  L  G L+VG+G G +    V  K  G K + KI        L GG++SITLRG+GHQF  GTE+SHIYR S  DFK  LI T H+ AV DIV+P    +LF TC+ +D+RV+H+ S +ELLRI +PNMTC+  D  +DG +II+ W+D KIRAF PETG LMY IN+AH+ GVTAIA TSDC++V+SGGGEG+VRVW+I  C+  +                        +E A+KEH ++VSCIR+ +++ +CV++S DGTCIIW L++  R Q++ ANTLF+CVC+ P+E QIITSGTDRKI YWEV+DG++IRELEGS SGS+NGMDIT +G  FVTGG+D +VKVW YNEG VTHVG+GHS  ITR+RISP  Q I +VS DGAI  WK+P
Sbjct:   10 QVAELELDAVIGFNGHVPTGLKCHPDQEHMIYPLGCTVLIQAINTKEQNFLQGHGNNVSCLAISRSGEYIASGQVTFMGFKADIILWDYKNRELLARLSLHKGKIEALAFSPNDLYLVSLGGPDDGSVVVWSIAKRDAICGSPAAGLNVGNATNVIFSRCRDEMFMTAGNGTIRVWELDLPNRKIWPTECQTGQLKRIVMSIGVDDDDSFFYLGTTTGDILKMNPRTKLLTDVGPAKDKFSLGVSAIRCLKMGGLLVGSGAGLL----VFCKSPGYKPIKKI-------QLQGGITSITLRGEGHQFLVGTEESHIYRVSFTDFKETLIATCHFDAVEDIVFPFGTAELFATCAKKDIRVWHTSSNRELLRITVPNMTCHGIDFMRDGKSIISAWNDGKIRAFAPETGRLMYVINNAHRIGVTAIATTSDCKRVISGGGEGEVRVWQI-GCQTQK------------------------LEEALKEHKSSVSCIRVKRNNEECVTASTDGTCIIWDLVRLRRNQMILANTLFQCVCYHPEEFQIITSGTDRKIAYWEVFDGTVIRELEGSLSGSINGMDITQEGVHFVTGGNDHLVKVWDYNEGEVTHVGVGHSGNITRIRISPGNQYIVSVSADGAILRWKYP 617          

Query:  332 DIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDGCVVIWSLTKMEPICGSPAQHKSAGITECLVYSNTNDDVFVTAGENTLRVWELDVENRKIRPTECSLGAIKRSIKCITISKDDSVFFCGTSSGDILGVNMKSCLLSCIGPEKETFSLGVLSIIRLINGDLIVGAGDGTICQVKVVEKKEGNKIMPKIVKTSNSCMLVGGVSSITLRGQGHQFYAGTEKSHIYRFSLGDFKSELINTAHYSAVNDIVYPNNCPKLFVTCSFQDVRVFHSDSQKELLRINIPNMTCYTCDIFKDGTAIITGWDDSKIRAFYPETGALMYTINDAHKKGVTAIAATSDCRKVVSGGGEGQVRVWRIEECKVSQANTIPHSHGNRKKSNVKSVVYVAHMETAMKEHANAVSCIRMNKDDTQCVSSSADGTCIIWCLIKYTRKQIMFANTLFRCVCWRPDECQIITSGTDRKIGYWEVYDGSLIRELEGSRSGSVNGMDITADGDIFVTGGDDKIVKVWKYNEGYVTHVGLGHSMPITRLRISPDRQLITTVSEDGAIYFWKFP 2017
            DI+LWDY  ++ ++  SLHK K+++LAFSPN+ YL SLGG DDG VV+WS+ K + ICGSPA   + G    +++S   D++F+TAG  T+RVWELD+ NRKI PTEC  G +KR +  I +  DDS F+ GT++GDIL +N ++ LL+ +GP K+ FSLGV +I  L  G L+VG+G G +    V  K  G K + KI        L GG++SITLRG+GHQF  GTE+SHIYR S  DFK  LI T H+ AV DIV+P    +LF TC+ +D+RV+H+ S +ELLRI +PNMTC+  D  +DG +II+ W+D KIRAF PETG LMY IN+AH+ GVTAIA TSDC++V+SGGGEG+VRVW+I  C+  +                        +E A+KEH ++VSCIR+ +++ +CV++S DGTCIIW L++  R Q++ ANTLF+CVC+ P+E QIITSGTDRKI YWEV+DG++IRELEGS SGS+NGMDIT +G  FVTGG+D +VKVW YNEG VTHVG+GHS  ITR+RISP  Q I +VS DGAI  WK+P
Sbjct:   24 DIILWDYKNRELLARLSLHKGKIEALAFSPNDLYLVSLGGPDDGSVVVWSIAKRDAICGSPAAGLNVGNATNVIFSRCRDEMFMTAGNGTIRVWELDLPNRKIWPTECQTGQLKRIVMSIGVDDDDSFFYLGTTTGDILKMNPRTKLLTDVGPAKDKFSLGVSAIRCLKMGGLLVGSGAGLL----VFCKSPGYKPIKKI-------QLQGGITSITLRGEGHQFLVGTEESHIYRVSFTDFKETLIATCHFDAVEDIVFPFGTAELFATCAKKDIRVWHTSSNRELLRITVPNMTCHGIDFMRDGKSIISAWNDGKIRAFAPETGRLMYVINNAHRIGVTAIATTSDCKRVISGGGEGEVRVWQIG-CQTQK------------------------LEEALKEHKSSVSCIRVKRNNEECVTASTDGTCIIWDLVRLRRNQMILANTLFQCVCYHPEEFQIITSGTDRKIAYWEVFDGTVIRELEGSLSGSINGMDITQEGVHFVTGGNDHLVKVWDYNEGEVTHVGVGHSGNITRIRISPGNQYIVSVSADGAILRWKYP 549          

Query:   86 EINKLELINVIGFNGTILDGLHVHPDRQHIIYGLGCTVVIEDLNTKNQCFLQGHTNNVVCITVSNSGKYIASGQITHMGYKADI 337
            ++ +LEL  VIGFNG +  GL  HPD++H+IY LGCTV+I+ +NTK Q FLQGH NNV C+ +S SG+YIASGQ+T MG+K   
Sbjct:   10 QVAELELDAVIGFNGHVPTGLKCHPDQEHMIYPLGCTVLIQAINTKEQNFLQGHGNNVSCLAISRSGEYIASGQVTFMGFKTSF 93          

Query: 1523 METAMKEHANAVSCIRMNKDDTQCVSSSADGTCIIWCLIKYTRKQIMFANTLFRCVCWRPDECQIITSGTDRKI 1744
            +E A+KEH ++VSCIR+ +++ +CV++S DGTCIIW L++  R Q++ ANTLF+CVC+ P+E QIITSGTDRK+
Sbjct:    5 LEEALKEHKSSVSCIRVKRNNEECVTASTDGTCIIWDLVRLRRNQMILANTLFQCVCYHPEEFQIITSGTDRKV 78          

Query:   98 LELINVIGFNGTILDGLHVHPDRQHIIYGLGCTVVIEDLNTKNQCFLQGHTNNVVCITVSNSGKYIASGQ-ITHMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDGCVVIW--------SLTKM-EPICGSPAQHKSAGITECLVYSNTNDDVFVTAGENTLRVWELDVENRKI------RPTECSLGAIKRSIKCITISKDDSVFFCGTSSGDILGVNMKS--CLLSCIGPEKETFSLGVL--SIIRLINGDLIVGAGDGTICQVKVVEKK--EGNKIMPKIVKTSNSCMLVGGVSSITLRGQGHQFYAGTEKSHIYRFSLGDFKSELINTAHYSAVNDIVYP---NNCPKLFVTCSFQ-DVRVFHSDSQKELLRINIPNMTCY------TCDIFKDGTAIITGWDDSKIRAFYPETGALMYTINDAHKKGVTAIAATSDCRKVVSGGGEGQVRV 1420
            L L  V+G++G     +   PD     Y  G  VV+EDL++  Q    GH+  +  + +S+S + +AS    +       I +WD     C      H   V +LAFSP+++ L +LG  D   + +W        S T++ EP+ G       AG   C+             G+ T+  W L      I       P   ++GA + +  C        + +CGTSSG +   + ++  C LS    E +   +G+L  S  RL++G      G   +  V  V +   +G+      V   +  +L G V S +          GT    ++  S  +  S  + + H S VN++V+    ++C     TCS    VRV+   S + +++  + N +C        C    +   +  G+ D  +R F     A+   ++  H   +T +A ++D + V+SG  +G V V
Sbjct: 1108 LRLKAVVGYSGNGRANMVWRPDTGFFAYTCGRLVVVEDLHSGAQQHWSGHSAEISTLALSHSAQVLASASGRSSTTAHCQIRVWDVSGGLCQHLIFPHSTTVLALAFSPDDRLLVTLGDHDGRTLALWGTATYDLVSSTRLPEPVHGVAFNPWDAGELTCV-------------GQGTVTFWLLQQRGADISLQVRREPVPEAVGAGELTSLCYGAPP---LLYCGTSSGQVCVWDTRAGRCFLSW---EADDGGIGLLLFSGSRLVSGS---STGRLRLWAVGAVSELRCKGSGARSSSVFMEHELVLDGAVVSASFDDSVDMGVVGTTAGTLWFVSWAEGTSTRLISGHRSKVNEVVFSPGESHC----ATCSEDGSVRVWALASMELVIQFQVLNQSCLCLAWSPPCCGRPEQQRLAAGYGDGSLRIFSVSRTAMELKMHP-HPVALTTVAFSTDGQTVLSGDKDGLVAV 1553          

Query:   98 LELINVIGFNGTILDGLHVHPDRQHIIYGLGCTVVIEDLNTKNQCFLQGHTNNVVCITVSNSGKYIASGQITHMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDG--CVVIWSLTKMEPICGSPAQHKSAGITECLVYSNTNDDV------------FVTAGENTLRVWELDVENRKIRPTECSLG---AIKRSIKCITISKDD------SVFFCGTSSGDILGVNMKSCLL------------SCIGPEKETFSLG---VLSIIRLINGDLIVGAGDGTICQVKVVEKKEGNKIMPKIVKTSNSCMLV-----GGVSSITLRGQGHQFYAGTEKSHIYRFSLGDFKSELINTAHYSAVNDIVYPNNCPKLFVTCSFQDVRVFHSDSQKELLRINIPNMTCYTCDIFKDGTAIITGWDDSKIRAFYPETGALMYTINDAHKKGVTAIAATSDCRKVVSGGGEG----------QVRVWRIEECKV-SQANTIPHSHGNRKKSNVKSVVYVAHMETAMKEHANAVSCIRMNKDDTQCVSSSADGTCIIWCLIKYTRKQIMFANTLFRCVCWRPDEC-QIITSGTDRKIGYWEVYDGSLIRELEGSRSGSVNGMDITADGDIFVTGGDDKIVKVWKY--NEGYVTHVGLGHSMPITRLRISPDRQLITTVSEDGAIYFW 2008
            L L  VIGF G         PD   ++Y     +V+  ++T  Q F  GHT+ V  + +  S   +AS Q       + + LWD+ T +C+  F      V SL+FS +   L  +G    G   VV W             Q    G    L  ++T+ DV              + G+ ++R+W L      +R     LG   A++ +      ++D       ++ F  + SG IL ++ +  ++                P+K+TFS G    +S + +      VG+ DG +                ++     S +L+     G VSS+ +   G +  + T   H+           ++  +H + V  +       +L      + VR++   + ++L                        G+    +R+F  E   ++   +  H+  VT + AT D R + S   +G          Q  V R+    V   A   P +    +   + + V  +     +   A+    +R++       SS  D                         VC+ P     ++ S +  ++   +   G +IREL G        + ++ D    +     + +KVW Y         V +GHS P+  +  SPD+Q +  +S   A++ W
Sbjct:  359 LRLKGVIGFGGHGTRQALWTPDGAAVVYPCHAVIVVLLVDTGEQRFFLGHTDKVSALALDGSSSLLASAQAR---APSVMRLWDFQTGRCLCLFRSPMHVVCSLSFSDSGALLCGVGKDHHGRTMVVAWGT----------GQVGLGGEVVVLAKAHTDFDVQAFRVTFFDETRMASCGQGSVRLWRL--RGGVLRSCPVDLGEHHALQFTDLAFKQARDGCPEPSAAMLFVCSRSGHILEIDCQRMVVRHARRLLPTRTPGGPHPQKQTFSSGPGIAISSLSVSPAMCAVGSEDGFL----------------RLWPLDFSSVLLEAEHEGPVSSVCVSPDGLRVLSATSSGHLGFLDTLSRVYHMLARSHTAPVLALAMEQRRGQLATVSQDRTVRIWDLATLQQLYDFTSSEDAPCAVTFHPTRPTFFCGFSSGAVRSFSLEAAEVLVE-HTCHRGAVTGLTATPDGRLLFSSCSQGSLAQYSCADPQWHVLRVAADMVCPDAPASPSALAVSRDGRLLAFVGPSRCTVTVMGSASLDELLRVDIGTLDLASSRLDSA---------------------MAVCFGPAALGHLLVSTSSNRVVVLDAVSGRIIRELPGVHPEPCPSLTLSEDARFLLIAA-GRTIKVWDYATQASPGPQVYIGHSEPVQAVAFSPDQQQV--LSAGDAVFLW 996          

Query: 1322 TINDAHKKGVTAIAATSDCRKVVSGGGEGQVRVWRIEECKVSQANTIPHSHGNRKKSNVKSVVYVAHMETAMKEHANAVSCIRMNKDDTQCVSSSADGTCIIWCLIKYTRKQIMFAN-TLFRCVCWRPDECQIITSGTD--RKIGYWEVYDGSLIRELEGSRSGSVNGMDITADGDIFVTGGDDKIVKVWKYNEGYVTHVGLGHSMPITRLRISPDRQ-LITTVSEDGAIYFW 2008
            TI  AH   + A+   S+ + ++S    G V+ W                     + N+ +    AHM +A K+   A+  +     D +  ++S DGT  +W   +YT ++++  +    RC+ W P +  I T   D  + +  W+   GS +  L+  +S SV  ++   +G+  +TGG D +VK++             H   +  L   P  + L  +   DG+I +W
Sbjct:  180 TILQAHDSAIRALKWASNEQWLLSADQGGYVKYW---------------------QPNMNN----AHMFSAHKD--EAIRGLAFAPTDVKFATASDDGTARVWDFARYTEERVLRGHGAEVRCIDWHPTKGLIATGSRDTQQPVKIWDPKSGSCLATLQEHKS-SVMAVEFNKNGNWLLTGGRDHLVKMYDIRMMKEMRTYRAHKKEVISLAWHPIHEGLFVSGGGDGSIVYW 384          

Query: 1256 IITGWDDSKIRAFYPETGALMYTINDAHKKGVTAIAATSDCRKVVSGGGEGQVRVWRIEECKV--------------SQANTIPHSHGNRKKSNVKSVVYVAHMETAMKEHANAVSCIRMNKDDTQCVSSSADGTCIIW------CLIKYTRKQIMFANTLFRCVCWRPDECQIITSGT-DRKIGYWEVY--DGSLIRELEGSRSGSVNGMDITADGDIFVTGGDDKIVKVWKYNEGYVTHVGLGHSMPITRLRISPDRQLITTVSEDGAIYFW 2008
            ++TG DD+ ++ +  + G +MYT+   H  GV     +   R +VSG  +  V+VW   +  +              + A +I  +        V  V    H+ T    HA AV C++   D T  VS   D T  IW      C+   T       + LF        E  I+ SG+ D  I  W+    +G     L    +   +GM +   G+I V+   D  V+VW  +EG   H+  GH   IT L+    R ++ T S+DG +  W
Sbjct:  267 LVTGSDDNTLKVWCIDKGEVMYTLV-GHTGGVWTSQISQCGRYIVSGSTDRTVKVWSTVDGSLLHTLQGHTSTVRCMAMAGSILVTGSRDTTLRVWDVESGRHLATLHGHHA-AVRCVQF--DGTTVVSGGYDFTVKIWNAHTGRCIRTLTGHNNRVYSLLFES------ERSIVCSGSLDTSIRVWDFTRPEGQECVALLQGHTSLTSGMQLR--GNILVSCNADSHVRVWDIHEGTCVHMLSGHRSAITSLQWF-GRNMVATSSDDGTVKLW 527          

Query: 1550 NAVSCIRMNKDDTQCVSSSADGTCIIWCLIKYTRKQIMFANTLFRCVCWRPDECQ----IITSGTDRKIGYWEVYDGSLIRELEG------------------SRSGSVNGMDITA-------------------DGDIFVTGGDDKIVKVWKYNEGYVTHVGLGHSMPITRLRISPDRQLITTVSEDGAIYFWKF 2014
            + ++C++++ D    V+ S D T  +WC+ K    ++M+         W     Q    I++  TDR +  W   DGSL+  L+G                  SR  ++   D+ +                   DG   V+GG D  VK+W  + G       GH+  +  L    +R ++ + S D +I  W F
Sbjct:  255 HVITCMQIHDD--VLVTGSDDNTLKVWCIDK---GEVMYTLVGHTGGVWTSQISQCGRYIVSGSTDRTVKVWSTVDGSLLHTLQGHTSTVRCMAMAGSILVTGSRDTTLRVWDVESGRHLATLHGHHAAVRCVQFDGTTVVSGGYDFTVKIWNAHTGRCIRTLTGHNNRVYSLLFESERSIVCSGSLDTSIRVWDF 445          

Query: 1256 IITGWDDSKIRAFYPETGALMYTINDAHKKGVTAIAATSDCRKVVSGGGEGQVRVWRIEECKV--------------SQANTIPHSHGNRKKSNVKSVVYVAHMETAMKEHANAVSCIRMNKDDTQCVSSSADGTCIIW------CLIKYTRKQIMFANTLFRCVCWRPDECQIITSGT-DRKIGYWEVY--DGSLIRELEGSRSGSVNGMDITADGDIFVTGGDDKIVKVWKYNEGYVTHVGLGHSMPITRLRISPDRQLITTVSEDGAIYFW 2008
            ++TG DD+ ++ +  + G +MYT+   H  GV     +   R +VSG  +  V+VW   +  +              + A +I  +        V  V    H+ T    HA AV C++   D T  VS   D T  IW      C+   T       + LF        E  I+ SG+ D  I  W+    +G     L    +   +GM +   G+I V+   D  V+VW  +EG   H+  GH   IT L+    R ++ T S+DG +  W
Sbjct:  267 LVTGSDDNTLKVWCIDKGEVMYTLV-GHTGGVWTSQISQCGRYIVSGSTDRTVKVWSTVDGSLLHTLQGHTSTVRCMAMAGSILVTGSRDTTLRVWDVESGRHLATLHGHHA-AVRCVQF--DGTTVVSGGYDFTVKIWNAHTGRCIRTLTGHNNRVYSLLFES------ERSIVCSGSLDTSIRVWDFTRPEGQECVALLQGHTSLTSGMQLR--GNILVSCNADSHVRVWDIHEGTCVHMLSGHRSAITSLQWF-GRNMVATSSDDGTVKLW 527          

Query: 1550 NAVSCIRMNKDDTQCVSSSADGTCIIWCLIKYTRKQIMFANTLFRCVCWRPDECQ----IITSGTDRKIGYWEVYDGSLIRELEG------------------SRSGSVNGMDITA-------------------DGDIFVTGGDDKIVKVWKYNEGYVTHVGLGHSMPITRLRISPDRQLITTVSEDGAIYFWKF 2014
            + ++C++++ D    V+ S D T  +WC+ K    ++M+         W     Q    I++  TDR +  W   DGSL+  L+G                  SR  ++   D+ +                   DG   V+GG D  VK+W  + G       GH+  +  L    +R ++ + S D +I  W F
Sbjct:  255 HVITCMQIHDD--VLVTGSDDNTLKVWCIDK---GEVMYTLVGHTGGVWTSQISQCGRYIVSGSTDRTVKVWSTVDGSLLHTLQGHTSTVRCMAMAGSILVTGSRDTTLRVWDVESGRHLATLHGHHAAVRCVQFDGTTVVSGGYDFTVKIWNAHTGRCIRTLTGHNNRVYSLLFESERSIVCSGSLDTSIRVWDF 445          

Query: 1256 IITGWDDSKIRAFYPETGALMYTINDAHKKGVTAIAATSDCRKVVSGGGEGQVRVWRIEECKV--------------SQANTIPHSHGNRKKSNVKSVVYVAHMETAMKEHANAVSCIRMNKDDTQCVSSSADGTCIIW------CLIKYTRKQIMFANTLFRCVCWRPDECQIITSGT-DRKIGYWEVY--DGSLIRELEGSRSGSVNGMDITADGDIFVTGGDDKIVKVWKYNEGYVTHVGLGHSMPITRLRISPDRQLITTVSEDGAIYFW 2008
            ++TG DD+ ++ +  + G +MYT+   H  GV     +   R +VSG  +  V+VW   +  +              + A +I  +        V  V    H+ T    HA AV C++   D T  VS   D T  IW      C+   T       + LF        E  I+ SG+ D  I  W+    +G     L    +   +GM +   G+I V+   D  V+VW  +EG   H+  GH   IT L+    R ++ T S+DG +  W
Sbjct:  269 LVTGSDDNTLKVWCIDKGEVMYTLV-GHTGGVWTSQISQCGRYIVSGSTDRTVKVWSTVDGSLLHTLQGHTSTVRCMAMAGSILVTGSRDTTLRVWDVESGRHLATLHGHHA-AVRCVQF--DGTTVVSGGYDFTVKIWNAHTGRCIRTLTGHNNRVYSLLFES------ERSIVCSGSLDTSIRVWDFTRPEGQECVALLQGHTSLTSGMQLR--GNILVSCNADSHVRVWDIHEGTCVHMLSGHRSAITSLQWF-GRNMVATSSDDGTVKLW 529          

Query: 1550 NAVSCIRMNKDDTQCVSSSADGTCIIWCLIKYTRKQIMFANTLFRCVCWRPDECQ----IITSGTDRKIGYWEVYDGSLIRELEG------------------SRSGSVNGMDITA-------------------DGDIFVTGGDDKIVKVWKYNEGYVTHVGLGHSMPITRLRISPDRQLITTVSEDGAIYFWKF 2014
            + ++C++++ D    V+ S D T  +WC+ K    ++M+         W     Q    I++  TDR +  W   DGSL+  L+G                  SR  ++   D+ +                   DG   V+GG D  VK+W  + G       GH+  +  L    +R ++ + S D +I  W F
Sbjct:  257 HVITCMQIHDD--VLVTGSDDNTLKVWCIDK---GEVMYTLVGHTGGVWTSQISQCGRYIVSGSTDRTVKVWSTVDGSLLHTLQGHTSTVRCMAMAGSILVTGSRDTTLRVWDVESGRHLATLHGHHAAVRCVQFDGTTVVSGGYDFTVKIWNAHTGRCIRTLTGHNNRVYSLLFESERSIVCSGSLDTSIRVWDF 447          

Query: 1571 MNKDDTQCVSSSADGTCIIWCL--------IKY-TRKQIMFANTLFRCVCWRPDECQIITSGTDRKIGYWEVYDGSLIRELEGSRSGSVNGMDITADGDIFVTGGDDKIVKVWKYNEGYVTHVGLGHSMPITRLRISPDRQLITTVSEDGAIYFW 2008
             + D    VS S DG   +W          +KY  +  +M  +   RC+ +  D   + T   D KI  W+V  G  +R  + + +  V  +  + D    ++GG+D +V+V     G       GHS  IT +R S +   I + S DG+I  W
Sbjct:  222 FSPDANYLVSGSKDGFIEVWNYMNGKLRKDLKYQAQDNLMMMDAAVRCISFSRDSEMLATGSIDGKIKVWKVETGDCLRRFDRAHTKGVCAVRFSKDNSHILSGGNDHVVRVHGMKSGKCLKEMRGHSSYITDVRYSDEGNHIISCSTDGSIRVW 376          

Query:  113 VIGFNGTILDGLHVHPDRQHIIYGLGCTVVIEDLNTKNQCFLQGHTNNVVCITVSNSGKYIASGQITHMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDGCVVIWSLTKMEPICGSPAQHKSAGITECLVYSNTNDDVFVTAGENTLRVWELDVENRKIRPTECSLGAIKRSIKCITISKDDSVFFCGTSSGDILGVNMK-------------SCLLSCIG---PEKET------FSLGVLSIIRLINGDLIVGAGDGTI------CQVKVVEKKEGNKIMPKIVKTSNSCMLVGGVSSITLRGQGHQFYAGTEKSHIYRFSLGDFKSELINTAHYSAVNDIVYPNNCPKLFVTCSFQDVRVFHSDSQKELLRINIPNMTCYTCDIFKDGTAIITGWDDSKIRAFYPETGALMYTINDAHKKGVTAIAATSDCRKVVSGGGEGQVRVWRIEECKVSQANTIPHSHGNRKKSNVKSVVYVAHMETAMKEHANAVSCIRMNKDDTQCVSSSADGTCIIWCLIKYTRKQIMFANTLFRCVCWRPDECQIITSGTDRKIGYWEVYDGSLIRELEGSRSGSVNGMDITADGDIFVTGGDDKIVKVWKYNEGYVTHVGLGHSMPITRLRISPDRQLITTVSEDGAIYFWKFPNN 2023
            + G NG + +G+  HP    II+ LG  + I D     Q F+ GHTN + C+ +S SGKY+ASGQI HMG++  +++W+Y  ++ ++   LHKV VQ++ F+  ++ + S+GG DDG V+++ +    PIC +PA    +G    +   + N   FVTAG+  LR+W +  E +K+   +  + +  R   C  I+K D   + GT +GDI+ + +              SC+L   G   P K T      +  GV ++  L  G L++GAG+G I        V ++  ++        ++T     + G +SS  +R +   FY  T+ + IY  ++  +  +L+ T H  +V  I +P N   +F T   + +R++ S  ++ELLRI + N  C       DGT+I++ W+D  IRAF P TG L+Y I +AH KG +A+A  S  R +V+GG EGQVRVW+I+                          Y   +   +K+H+  ++ + +N  DT+ +S+  DG+C+IW + + TRKQ++ ANT F    + P   Q+IT G+D +I YW VY+G+LIREL  S+  SVN + I   GD F+T G D  VK+W YN G V  +G  H+  +     SP   +  T S DG++  W  P +
Sbjct:   16 IFGINGKVENGVRQHPVTGSIIFALGNKIGIADYKKNTQEFVAGHTNTISCLDLSKSGKYMASGQINHMGFRGYVIIWNYDQRKEIARHDLHKVSVQAICFTAQDRCVVSIGGVDDGSVIVFDMEAFSPICQTPASRAISGNALTVRPLHNNPYFFVTAGDRHLRLWSILREEKKLYVQDVLMASKTRVFYCARINKTDEFAYLGTGTGDIVKIVLNCCDRDHVSKQGSTSCILGAFGTHNPRKPTGRDCNRYVNGVRALYVLEGGRLLIGAGNGDIELVEERTDVPLINFRDYPGPTWPYLRTLKKTHVSGRISSF-VRSKTDMFYICTDTNEIYGLNIKTWVLKLLRTCHTKSVYCITFPKNYSGVFATSGKECIRIWSSGRKQELLRIMVYNFNCACVRFTHDGTSIVSVWNDGIIRAFTPITGRLIYAIPNAHNKGCSALAVASSGRLIVTGGIEGQVRVWKIDP-------------------------YRQDLVGVLKDHSGPITSLDINYLDTEVISACTDGSCVIWDIKRMTRKQVVTANTQFMSASYFPTGVQVITCGSDGRIIYWMVYNGALIRELTASKKSSVNCLAINETGDYFITVGSDLQVKLWDYNSGAVVGIGSEHASSVISCAYSPCMTMFVTGSTDGSLIIWDVPRD 654          

Query: 1523 METAMKEHANAVSCIRMNKDDTQCVSSSADGTCIIWCLIKYTRKQIMFAN--TLFRCVCWRPDECQIITSGTDRKIGYWEVYDGSLIRELEG---SRSGSVNGMDITADGDIFVTGGDDKIVKVWKYNEGYVTHVGLGHSMPITRLRISPDRQLITTVSEDGAI 1999
            +E     H+  ++ +R   D  Q  +SS D T I+W L +  R  I FA+       V W P    + ++G DR +  WE      +R + G   + S +V  +D  + G + +T  DDK  K+W+             +  +   + SP+ +L+ T S+D ++
Sbjct:   10 LERHFTGHSGGITQLRFGPDGAQIATSSTDSTVILWNLNQAARC-IRFASHSAPVNGVAWSPKGNLVASAGHDRTVKIWE----PKLRGVSGEFVAHSKAVRSVDFDSTGHLMLTASDDKSAKIWRVARRQFVSSFAQQNNWVRSAKFSPNGKLVATASDDKSV 168          

Query: 1385 VVSGGGEGQVRVWRIEECKVSQANTIPHSHGNRKKSNVKSVVYVAHMETAMKEHANAVSCIRMNKDDTQCVSSSADGTCIIWCLIKYTRKQIM-FANTLFRCVCWRPDECQIITSGTDRKIGYWEVYDGSLIRELEGSRSGSVNGMDITADGDIFVTGGDDKIVKVWKYNEGYVTHVGLGHSMPITRLRISPDRQLITTVSEDGAIYFW 2008
            +V+GG +  V+VW ++E      NT+   H                    +K HA  V  + ++ D     SSS D T  +W      +K ++ F       V + P    +I+   D KI  + V  G   + L+         +  + DG    +G  D I+ ++    G V     GH+MP+  L  SP+ QL+ T S+DG +  +
Sbjct:   55 LVTGGLDDLVKVWDLQE-----DNTLKLRH-------------------KLKGHALGVVSVAVSSDGQTIASSSLDSTMCLWDARSGDKKHLLSFGPVDLWTVQFSPCNKYVISGLNDGKISMYSVETGKAEQTLDAQNGKYTLSIAYSPDGKYIASGAIDGIITIFDVAAGKVVQTLEGHAMPVRSLCFSPNSQLLLTASDDGHMKLY 239          

Query: 1523 METAMKEHANAVSCIRMNKDDTQCVSSSADGTCIIWCLIKYTRKQIMFAN--TLFRCVCWRPDECQIITSGTDRKIGYWEVYDGSLIRELEG---SRSGSVNGMDITADGDIFVTGGDDKIVKVWKYNEGYVTHVGLGHSMPITRLRISPDRQLITTVSEDGAIYFW 2008
            +E     H+  ++ +R   D  Q  +SS D T I+W L +  R  I FA+       V W P    + ++G DR +  WE      +R + G   + S +V  +D  + G + +T  DDK  K+W+             +  +   + SP+ +L+ T S+D ++  +
Sbjct:   10 LERHFTGHSGGITQLRFGPDGAQIATSSTDSTVILWNLNQAARC-IRFASHSAPVNGVAWSPKGNLVASAGHDRTVKIWEPK----LRGVSGEFVAHSKAVRSVDFDSTGHLMLTASDDKSAKIWRVARRQFVSSFAQQNNWVRSAKFSPNGKLVATASDDKSVRIY 171          

Query: 1274 DSKIRAFYPETGALMYTINDAHKKGVTAIAATSDCRKVVSGGGEGQVRVWRIEECKVSQA-----------NTIPHSHGNRKKSNVKSV----VYVAHMETAMKEHANAVSCIRMNKDDTQCVSSSADGTCIIW------CLIKYTRKQIMFANTLFRCVCWRPDECQIITSGTDRKIGYWEVYDGSLIRELEGSRSGS---VNGMDITADGDIFVTGGDDKIVKVWKYNEGYVTHVGLGHSMPITRLRISPDRQLITTVS--EDGAIYFWK 2011
            D  I+ +    G    TI+  HK G++ +A +SD R +VSG  +  ++VW +   K  +            N  P S+     S  +SV    V        +  H++ VS +  N+D +  VSSS DG C IW      CL    +  I   N     V + P+   I+ +  D  +  W+   G  ++   G ++          +T  G   V+G +D +V +W      V     GH+  +      P   +I + +   D  I  WK
Sbjct:   93 DKLIKIWGAYDGKFEKTIS-GHKLGISDVAWSSDSRLLVSGSDDKTLKVWELSTGKSLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVRTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCL----KTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTG-GKWIVSGSEDNMVYIWNLQSKEVVQKLQGHTDTVLCTACHPTENIIASAALENDKTIKLWK 358          

Query: 1523 METAMKEHANAVSCIRMNKDDTQCVSSSADGTCIIWCLIKYTRKQIMFANTL-FRCVCWRPDECQIITSGTDRKIGYWEVYDGSLIRELEGSRSGSVNGMDITADGDIFVTGGDDKIVKVWKYNEGYVTHVGLGHSMPITRLRISPDRQLITTVSEDGAIYFW 2008
            ++  +  H  AVS ++ + +     SSSAD    IW       ++ +  + L    V W  D   +++   D+ +  WE+  G  ++ L+G  S  V   +     ++ V+G  D+ V++W    G        HS P++ +  + D  LI + S DG    W
Sbjct:   64 LKFTLAGHTKAVSAVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSRLLVSGSDDKTLKVWELSTGKSLKTLKG-HSNYVFCCNFNPQSNLIVSGSFDESVRIWDVRTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIW 225          

Query: 1643 YTRKQIMFANT-LFRCVCWRPDECQIITSGTDRKIGYWEVYDGSLIRELEGSRSGSVNGMDITADGDIFVTGGDDKIVKVWKYNEGYVTHVGLGHSMPITRLRISPDRQLITTVSEDGAIYFW 2008
            YT K  +  +T     V + P+   + +S  D+ I  W  YDG   + + G + G ++ +  ++D  + V+G DDK +KVW+ + G       GHS  +     +P   LI + S D ++  W
Sbjct:   62 YTLKFTLAGHTKAVSAVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLG-ISDVAWSSDSRLLVSGSDDKTLKVWELSTGKSLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIW 183          

Query: 1508 VYVAHMETAMKEHANAVSCIRMNKDDTQCVSSSADGTCIIWCLI--KYTRKQIMFANTLFRCVCWRPDECQIITSGTDRKIGYWEVYDGSLIRELEGSRSGSVNGMDITADGDIFVTGGDDKIVKVWKYNEGYVTHVGLGH-SMPITRLRISPDRQLITTVSEDGAIYFWKF 2014
             Y    E  +  H   +S +  + D    VS S D T  +W L   K  +     +N +F C  + P    I++   D  +  W+V  G  ++ L  + S  V+ +    DG + V+   D + ++W    G      +   + P++ ++ SP+ + I   + D  +  W +
Sbjct:  101 AYDGKFEKTISGHKLGISDVAWSSDSRLLVSGSDDKTLKVWELSTGKSLKTLKGHSNYVF-CCNFNPQSNLIVSGSFDESVRIWDVRTGKCLKTLP-AHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDY 270          

Query:   71 GEEVNEINKLELINVIGFNGTILDGLHVHPDRQHIIYGLGCTVVIEDLNTKNQCFLQGHTNNVVCITVSNSGKYIASGQITHMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDGCVVIWSLTKMEPICGSPAQHKSAGITECLVYSNTNDDVFVTAGENTLRVWELDVENRKIRPTECSLGAIKRSIKCITISKDDSVFFCGTSSGDILGVNMKSCLLSCIGPEKETFSLGVLSIIRLINGDLIVGAGDG--TICQVKVVEKKEGNKIMPKIVKTSNSCMLVGGVSSITLRGQGHQFYAGTEKSHIYRFSLGDFKSELINTAHYSAVNDIVYPNNCPKLFVTCSFQDVRVFHSDSQKELLRINIPNMTCYTCDIFKDGTAIITGWDDSKIRAFYPETGALMYTINDAHKKGVTAIAATSDCRKVVSGGGEGQVRVWRIEECKVSQANTIPHSHGNRKKSNVKSVVYVAHMETAMKEHANAVSCIRMNKDDTQCVSSSADGTCIIWCLIKYTRKQIMFANTLFRCVCWRPDECQIITSGTDRKIGYWEVYDGSLIRELEGSRSGSVNGMDITADGDIFVTGGDDKIVKVWKYNEGYVTHVGLGHSMPITRLRISPDRQLITTVSEDGAIYFWKFPN 2020
             E+  E+ +L L  VIGFNG +  GL VHPD++H+IY LGCTV+I+ L +  Q FL GHTNNV CI+VS SG+YIASGQ+T MG+KAD+++WDY  K+  +   LHK KV+ L+FSPN+KYL SLGGQDD  +V+W++   E ICGSPA  +SAG    L Y+N +D++FV+AG  TLRVWELD+ NRKIRPTEC  G +KR +KC+ I  DD+ F+CGT+SGDIL VN+K+ LL+  GP K+ FS GV ++  L  GD++VG+GDG  T+C                  KT  S  L GGV+S+TLRG GHQFY GTE + +Y  S  DFK EL  T H SAV D+ +P    +LF TCS  D+RV+HS+S KELLRI +PN+TC+     +DG +I + W+D KIR F PE+G L   I++AH   VT IAAT+DC+++VSGGGEGQVRVW I +       T                         MKEH   V+CI++  +D +CV++S+DG CIIW L+++ R Q++ +NTLF  VC+ P+E QIITSGTDRKIGYWEVYDGS IRELEGS SGS+NGM I+ DG  FVTGGDDK++K+W Y++G VTHVG+GHS  IT +RI P+ + I + S DGAI  W++P 
Sbjct:    2 AEDTQEVPQLALEAVIGFNGHVFSGLKVHPDKEHLIYPLGCTVIIKSLRSGKQSFLHGHTNNVSCISVSKSGRYIASGQVTFMGFKADVIIWDYEKKEIYARLLLHKAKVEDLSFSPNDKYLVSLGGQDDASIVVWNIESKEAICGSPASAQSAGHCLALEYTNLSDEIFVSAGNGTLRVWELDLLNRKIRPTECQTGQLKRIVKCLEIPNDDNYFYCGTTSGDILKVNLKTRLLNSCGPVKQKFSKGVNTLKVLKTGDILVGSGDGMLTLCS-------------GANFKTIKSVQLEGGVTSVTLRGDGHQFYVGTEAAQMYSLSYTDFKPELTATNHNSAVKDVAFPFGTSELFATCSHNDIRVWHSESSKELLRITVPNITCHALGFMRDGRSIFSAWNDGKIRVFTPESGKLKLIIHNAHSMAVTTIAATNDCKRIVSGGGEGQVRVWEIFQDSYRLIET-------------------------MKEHKATVNCIKIKSNDKECVTASSDGACIIWDLVRFVRNQMVLSNTLFSVVCYHPEEYQIITSGTDRKIGYWEVYDGSAIRELEGSLSGSINGMHISEDGKYFVTGGDDKLLKLWLYSDGEVTHVGIGHSGSITNVRICPNSRYIVSTSADGAILRWRYPQ 615          

Query:   71 GEEVNEINKLELINVIGFNGTILDGLHVHPDRQHIIYGLGCTVVIEDLNTKNQCFLQGHTNNVVCITVSNSGKYIASGQITHMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDGCVVIWSLTKMEPICGSPAQHKSAGITECLVYSNTNDDVFVTAGENTLRVWELDVENRKIRPTECSLGAIKRSIKCITISKDDSVFFCGTSSGDILGVNMKSCLLSCIGPEKETFSLGVLSIIRLINGDLIVGAGDG--TICQVKVVEKKEGNKIMPKIVKTSNSCMLVGGVSSITLRGQGHQFYAGTEKSHIYRFSLGDFKSELINTAHYSAVNDIVYPNNCPKLFVTCSFQDVRVFHSDSQKELLRINIPNMTCYTCDIFKDGTAIITGWDDSKIRAFYPETGALMYTINDAHKKGVTAIAATSDCRKVVSGGGEGQVRVWRIEECKVSQANTIPHSHGNRKKSNVKSVVYVAHMETAMKEHANAVSCIRMNKDDTQCVSSSADGTCIIWCLIKYTRKQIMFANTLFRCVCWRPDECQIITSGTDRKIGYWEVYDGSLIRELEGSRSGSVNGMDITADGDIFVTGGDDKIVKVWKYNEGYVTHVGLGHSMPITRLRISPDRQLITTVSEDGAIYFWKFPN 2020
             ++  E+ +L L  VIGFNG +  GL VHPD++H+IY LGCTV+I+ L +  Q FL GHTNNV CI+VS SG+YIASGQ+T MG+KAD+++WDY  K+  +   LHK KV+ L+FSPN+KYL SLGGQDD  +V+W++   E ICGSPA  +SAG    L Y+N +D++FV+AG  TLRVWELD+ NRKIRPTEC  G +KR +KC+ I  DD+ F+CGT+SGDIL VN+K+ LL+  GP K+ FS GV ++  L  GD++VG+GDG  T+C                  KT  S  L GGV+S+TLRG GHQFY GTE + +Y  S  DFK EL  T H SAV D+ +P    +LF TCS  D+RV+HS+S KELLRI +PN+TC+     +DG +I + W+D KIR F PE+G L   I++AH   VT IAAT+DC+++VSGGGEGQVRVW I +       T                         MKEH   V+CI++  +D +CV++S+DG CIIW L+++ R Q++ +NTLF  VC+ P+E QIITSGTDRKIGYWEVYDGS IRELEGS SGS+NGM I+ DG  FVTGGDDK++K+W Y++G VTHVG+GHS  IT +RI P+ + I + S DGAI  W++P 
Sbjct:    2 ADDTQEVPQLALEAVIGFNGHVFSGLKVHPDKEHLIYPLGCTVIIKSLRSGKQSFLHGHTNNVSCISVSKSGRYIASGQVTFMGFKADVIIWDYEKKEIYARLLLHKAKVEDLSFSPNDKYLVSLGGQDDASIVVWNIESKEAICGSPASAQSAGHCLALEYTNLSDEIFVSAGNGTLRVWELDLLNRKIRPTECQTGQLKRIVKCLEIPNDDNYFYCGTTSGDILKVNLKTRLLNSCGPVKQKFSKGVNTLKVLKTGDILVGSGDGMLTLCS-------------GANFKTIKSVQLEGGVTSVTLRGDGHQFYVGTEAAQMYSLSYTDFKPELTATNHNSAVKDVAFPFGTSELFATCSHNDIRVWHSESSKELLRITVPNITCHALGFMRDGRSIFSAWNDGKIRVFTPESGKLKLIIHNAHSMAVTTIAATNDCKRIVSGGGEGQVRVWEIFQDSYRLIET-------------------------MKEHKATVNCIKIKSNDKECVTASSDGACIIWDLVRFVRNQMVLSNTLFSVVCYHPEEYQIITSGTDRKIGYWEVYDGSAIRELEGSLSGSINGMHISEDGKYFVTGGDDKLLKLWLYSDGEVTHVGIGHSGSITNVRICPNSRYIVSTSADGAILRWRYPQ 615          

Query:   71 GEEVNEINKLELINVIGFNGTILDGLHVHPDRQHIIYGLGCTVVIEDLNTKNQCFLQGHTNNVVCITVSNSGKYIASGQITHMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDGCVVIWSLTKMEPICGSPAQHKSAGITECLVYSNTNDDVFVTAGENTLRVWELDVENRKIRPTECSLGAIKRSIKCITISKDDSVFFCGTSSGDILGVNMKSCLLSCIGPEKETFSLGVLSIIRLINGDLIVGAGDG--TICQVKVVEKKEGNKIMPKIVKTSNSCMLVGGVSSITLRGQGHQFYAGTEKSHIYRFSLGDFKSELINTAHYSAVNDIVYPNNCPKLFVTCSFQDVRVFHSDSQKELLRINIPNMTCYTCDIFKDGTAIITGWDDSKIRAFYPETGALMYTINDAHKKGVTAIAATSDCRKVVSGGGEGQVRVWRIEECKVSQANTIPHSHGNRKKSNVKSVVYVAHMETAMKEHANAVSCIRMNKDDTQCVSSSADGTCIIWCLIKYTRKQIMFANTLFRCVCWRPDECQIITSGTDRKIGYWEVYDGSLIRELEGSRSGSVNGMDITADGDIFVTGGDDKIVKVWKYNEGYVTHVGLGHSMPITRLRISPDRQLITTVSEDGAIYFWKFPN 2020
             ++  E+ +L L  VIGFNG +  GL VHPD++H+IY LGCTV+I+ L +  Q FL GHTNNV CI+VS SG+YIASGQ+T MG+KAD+++WDY  K+  +   LHK KV+ L+FSPN+KYL SLGGQDD  +V+W++   E ICGSPA  +SAG    L Y+N +D++FV+AG  TLRVWELD+ NRKIRPTEC  G +KR +KC+ I  DD+ F+CGT+SGDIL VN+K+ LL+  GP K+ FS GV ++  L  GD++VG+GDG  T+C                  KT  S  L GGV+S+TLRG GHQFY GTE + +Y  S  DFK EL  T H SAV D+ +P    +LF TCS  D+RV+HS+S KELLRI +PN+TC+     +DG +I + W+D KIR F PE+G L   I++AH   VT IAAT+DC+++VSGGGEGQVRVW I +       T                         MKEH   V+CI++  +D +CV++S+DG CIIW L+++ R Q++ +NTLF  VC+ P+E QIITSGTDRKIGYWEVYDGS IRELEGS SGS+NGM I+ DG  FVTGGDDK++K+W Y++G VTHVG+GHS  IT +RI P+ + I + S DGAI  W++P 
Sbjct:    2 ADDTQEVPQLALEAVIGFNGHVFSGLKVHPDKEHLIYPLGCTVIIKSLRSGKQSFLHGHTNNVSCISVSKSGRYIASGQVTFMGFKADVIIWDYEKKEIYARLLLHKAKVEDLSFSPNDKYLVSLGGQDDASIVVWNIESKEAICGSPASAQSAGHCLALEYTNLSDEIFVSAGNGTLRVWELDLLNRKIRPTECQTGQLKRIVKCLEIPNDDNYFYCGTTSGDILKVNLKTRLLNSCGPVKQKFSKGVNTLKVLKTGDILVGSGDGMLTLCS-------------GANFKTIKSVQLEGGVTSVTLRGDGHQFYVGTEAAQMYSLSYTDFKPELTATNHNSAVKDVAFPFGTSELFATCSHNDIRVWHSESSKELLRITVPNITCHALGFMRDGRSIFSAWNDGKIRVFTPESGKLKLIIHNAHSMAVTTIAATNDCKRIVSGGGEGQVRVWEIFQDSYRLIET-------------------------MKEHKATVNCIKIKSNDKECVTASSDGACIIWDLVRFVRNQMVLSNTLFSVVCYHPEEYQIITSGTDRKIGYWEVYDGSAIRELEGSLSGSINGMHISEDGKYFVTGGDDKLLKLWLYSDGEVTHVGIGHSGSITNVRICPNSRYIVSTSADGAILRWRYPQ 615          

Query:   56 KLRMS---GEEVNEINKLELINVIGFNGTILDGLHVHPDRQHIIYGLGCTVVI-EDLNTKNQCFLQGHTNNVVCITVSNSGKYIASGQITHMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDGCVVIWSLTKMEPICGSPAQHKSAGITECLVYSNTNDDVFVTAGENTLRVWELD-VENRKIRPT------ECSLGAIKRS----IKCITISKDDSVFFCGTSSGDILGVNMKSCLLSCIGPEK-ETFSLGVLSIIRLINGDLIVGAGDGTI 877
            KLR S     + N  NK+ L  V+G        L   P    I Y  GC VV+      K    +      +  ++ S  GKY+ +G+  HM     + +WD   +  V+    HK  V  ++FSPN KY+ S+G Q D  V +W+  K   +  +    K   ++    +S+ +   FVTAG   ++ W LD  ++ K+  T         LG ++ +    + C    K  S  FC T+SG +   N K  L   +   K ++F+  + + + +    +  G  DGT+
Sbjct:   22 KLRRSKAGNNKENLSNKVTLEKVLGITSAGSRALACDPHSGLIAYPAGCVVVLLNPKKNKQHHIINSSRKTITTVSFSPDGKYVVTGESGHMPA---VRVWDVAERTQVAELQEHKYGVACVSFSPNSKYIVSVGYQHDMIVNVWAWKKNVVVAANKVSSKVTAVS----FSD-DSSYFVTAGNRHVKFWYLDHTKSSKVNATVPLSGRSGLLGELRNNFFSDVACGKGRKASST-FCITTSGLLCEFNDKRMLDKWVELRKNDSFATSMATSLSVCEDLIFCGCADGTV 302          

Query:   56 KLRMS---GEEVNEINKLELINVIGFNGTILDGLHVHPDRQHIIYGLGCTVVI-EDLNTKNQCFLQGHTNNVVCITVSNSGKYIASGQITHMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDGCVVIWSLTKMEPICGSPAQHKSAGITECLVYSNTNDDVFVTAGENTLRVWELD-VENRKIRPT------ECSLGAIKRS----IKCITISKDDSVFFCGTSSGDILGVNMKSCLLSCIGPEK-ETFSLGVLSIIRLINGDLIVGAGDGTI 877
            KLR S     + N  NK+ L  V+G        L   P    I Y  GC VV+      K    +      +  ++ S  GKY+ +G+  HM     + +WD   +  V+    HK  V  ++FSPN KY+ S+G Q D  V +W+  K   +  +    K   ++    +S+ +   FVTAG   ++ W LD  ++ K+  T         LG ++ +    + C    K  S  FC T+SG +   N K  L   +   K ++F+  + + + +    +  G  DGT+
Sbjct:   22 KLRRSKAGNNKENLSNKVTLEKVLGITSAGSRALACDPHSGLIAYPAGCVVVLLNPKKNKQHHIINSSRKTITTVSFSPDGKYVVTGESGHMPA---VRVWDVAERTQVAELQEHKYGVACVSFSPNSKYIVSVGYQHDMIVNVWAWKKNVVVAANKVSSKVTAVS----FSD-DSSYFVTAGNRHVKFWYLDHTKSSKVNATVPLSGRSGLLGELRNNFFSDVACGKGRKASST-FCITTSGLLCEFNDKRMLDKWVELRKNDSFATSMATSLSVCEDLIFCGCADGTV 302          

Query:   77 EVNEINKLELINVIGFNGTILDGLHVHPDRQHIIYGLGCTVVIEDLNTKNQCFLQGHTNNVVCITVSNSGKYIASGQITHMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDGCVVIWSLTKMEPICGSPAQHKSAGITECLVYSNTNDDVFVTAGENTLRVWELDVENRKIRPTECSLGAIKRSIKCITISK-----DDSVFFCGTSSGDILGVNMKSCLLSCIGPEKETFSLGVLSIIRLINGDLIVGAGDGTICQVKVVEKKEGNKIMPKIVKTSNSCMLVGGVSSITLRGQGHQFYAGTEKSHIYRFSLGDFKSELINTAHYSAVNDIVYPNNCPKLFVTCSFQDVRVFHSDSQKELLRINIPNMTCYTCDIFKDGTAIITGWDDSKIRAFYPETGALMYTINDAHKKGVTAIAATSDCRKVVSGGGEGQVRVWRIEECKVSQANTIPHSHGNRKKSNVKSVVYVAHMETAMKEHANAVSCIRMNKDDTQCVSSSADGTCIIWCLIKYTRKQIMFANTLFRCVCWRPDECQIITSGTDRKIGYWEVYDGSLIRELEGSRSGSVNGMDITADGDIFVTGGDDKIVKVWKYNEGYVTHVGLGHSMPITRLRISPDRQLITTVSEDGAIYFWKFP 2017
            E  E N+LEL  +IGFNG +  GL  HPDR+H+IY LGCTV+IE+L+++ Q FLQGHTNNV C+  S SG+Y+ASGQ+T+MG+KADI+LWDY  ++  +  +LHKVKV++LAFSPN+ YL SLGGQDDG VV+W++ K E ICGSPA   S+G    ++++N +DD+F+T G  TLRVW++D+ NRK+RPTEC LG +KR + C+ ++      DDS F+CGTSSGDIL +N KS LLS   P+K  FSLGV ++  L  G+L+VG+GDG +   K               K + +  L G V+SI+LRGQGHQF+ GT  + IYRFS  +FK ELI T H  A+NDI +P    +LF TCS  D+RV+H+ + KELLRI +PNMTC   D  +DG +II+ W+D +IRAF PE+G LMY I +AH  GVTAIAATSDC+++VSGGGEGQVR+W I +                             +  +MKEH ++V+CI++  ++ +C+++S+DGTCIIW ++++TR Q++ +NTLFRCVC+ P+E Q +TSGTDRK+GYWEV+DGS IRELEGS+SG++NGMDI   G  FVTGGDDK+VKVW YNEG VTHVG+GHS  ITRL+I P  + I +VS DGAI  W +P
Sbjct:    3 EQGEDNRLELQGIIGFNGHVPSGLISHPDREHLIYPLGCTVIIENLSSRKQQFLQGHTNNVSCVAASRSGRYLASGQVTYMGFKADILLWDYGRREACAKLTLHKVKVEALAFSPNDLYLVSLGGQDDGSVVVWNVAKREAICGSPASSLSSGHATTIIFTNNSDDIFMTGGNGTLRVWDVDLPNRKMRPTECQLGQMKRVVTCLQVTSQSCFTDDSCFYCGTSSGDILTINTKSKLLSSFAPQKGKFSLGVTALRLLKTGELLVGSGDGKLALCKGPN-----------YKAAKTVQLQGSVTSISLRGQGHQFFVGTGGAQIYRFSYPEFKEELIATCHSEAINDIAFPFGTSELFATCSKNDIRVWHTATHKELLRITVPNMTCLAIDFMRDGKSIISAWNDGRIRAFMPESGRLMYCIENAHSMGVTAIAATSDCKRIVSGGGEGQVRIWEISK-------------------------ETQRLVQSMKEHKSSVTCIKLKGNNRECLTASSDGTCIIWDIVRFTRLQMVLSNTLFRCVCYHPEEFQFVTSGTDRKVGYWEVFDGSAIRELEGSKSGAINGMDICDQGAHFVTGGDDKLVKVWDYNEGEVTHVGIGHSGNITRLKICPLSKYIISVSTDGAILCWDYP 618          

Query:  101 ELINVIGFNGTILDGLHVHPDRQHIIYGLGCTVVIEDLNTKNQCFLQGHTNNVVCITVSNSGKYIASGQITHMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDGCVVIWSLTKMEPICGSPAQHKSAGITECLVYSNTNDDVFVTAGENTLRVWELDVENRKIRPTECSLGAIKRSIKCITISKDDSVFFCGTSSGDILGVNMKSCLLSCIGPEKETFSLGVLSIIRLINGDLIVGAGDGTICQVKVVEKKEGNKIMPKIVKTSNSCMLVGGVSSITLRGQGHQFYAGTEKSHIYRFSLGDFKSELINTAHYSAVNDIVYPNNCPKLFVTCSFQDVRVFHSDSQKELLRINIPNMTCYTCDIFKDGTAIITGWDDSKIRAFYPETGALMYTINDAHKKGVTAIAATSDCRKVVSGGGEGQVRVWRIEECKVSQANTIPHSHGNRKKSNVKSVVYVAHMETAMKEHANAVSCIRMNKDDTQCVSSSADGTCIIWCLIKYTRKQIMFANTLFRCVCWRPDECQIITSGTDRKIGYWEVYDGSLIRELEGSRSGSVNGMDITADGDIFVTGGDDKIVKVWKYNEGYVTHVGLGHSMPITRLRISPDRQLITTVSEDGAIYFWKFP 2017
            E++ V+  +G +  GL  HPDR+H+IY LGCTV+IE+L+++ Q FLQGHTNNV C+  S SG+Y+ASGQ+T+MG+KADI+LWDY  ++  +  +LHKVKV++LAFSPN+ YL SLGGQDDG VV+W++ K E ICGSPA   S+G    ++++N +DD+F+T G  TLRVW++D+ NRK+RPTEC LG +KR + C+ +++DDS F+CGTSSGDIL +N KS LLS   P+K  FSLGV ++  L  G+L+VG+GDG +   K               K + +  L G V+SI+LRGQGHQF+ GT  + IYRFS  +FK ELI T H  A+NDI +P    +LF TCS  D+RV+H+ + KELLRI +PNMTC   D  +DG +II+ W+D +IRAF PE+G LMY I +AH  GVTAIAATSDC+++VSGGGEGQVR+W I +                             +  +MKEH ++V+CI++  ++ +C+++S+DGTCIIW ++++TR Q++ +NTLFRCVC+ P+E Q +TSGTDRK+GYWEV+DGS IRELEGS+SG++NGMDI   G  FVTGGDDK+VKVW YNEG VTHVG+GHS  ITRL+I P  + I +VS DGAI  W +P
Sbjct:    4 EVLVVLSHSGHVPSGLISHPDREHLIYPLGCTVIIENLSSRKQQFLQGHTNNVSCVAASRSGRYLASGQVTYMGFKADILLWDYGRREACAKLTLHKVKVEALAFSPNDLYLVSLGGQDDGSVVVWNVAKREAICGSPASSLSSGHATTIIFTNNSDDIFMTGGNGTLRVWDVDLPNRKMRPTECQLGQMKRVVTCLQVAEDDSCFYCGTSSGDILTINTKSKLLSSFAPQKGKFSLGVTALRLLKTGELLVGSGDGKLALCKGPN-----------YKAAKTVQLQGSVTSISLRGQGHQFFVGTGGAQIYRFSYPEFKEELIATCHSEAINDIAFPFGTSELFATCSKNDIRVWHTATHKELLRITVPNMTCLAIDFMRDGKSIISAWNDGRIRAFMPESGRLMYCIENAHSMGVTAIAATSDCKRIVSGGGEGQVRIWEISK-------------------------ETQRLVQSMKEHKSSVTCIKLKGNNRECLTASSDGTCIIWDIVRFTRLQMVLSNTLFRCVCYHPEEFQFVTSGTDRKVGYWEVFDGSAIRELEGSKSGAINGMDICDQGAHFVTGGDDKLVKVWDYNEGEVTHVGIGHSGNITRLKICPLSKYIISVSTDGAILCWDYP 606          

Query:  113 VIGFNGTILDGLHVHPDRQHIIYGLGCTVVIEDLNTKNQCFLQGHTNNVVCITVSNSGKYIASGQITHMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDGCVVIWSLTKMEPICGSPAQHKSAGITECLVYSNTNDDVFVTAGENTLRVWELDVENRKIRPTECSLGAIKRSIKCITISKDDSVFFCGTSSGDILGVNMKSCLLSCIGPEKETFSLGVLSIIRLINGDLIVGAGDGTICQVKVVEKKEGNKIMPKIVKTSNSCMLVGGVSSITLRGQGHQFYAGTEKSHIYRFSLGDFKSELINTAHYSAVNDIVYPNNCPKLFVTCSFQDVRVFHSDSQKELLRINIPNMTCYTCDIFKDGTAIITGWDDSKIRAFYPETGALMYTINDAHKKGVTAIAATSDCRKVVSGGGEGQVRVWRIEECKVSQANTIPHSHGNRKKSNVKSVVYVAHMETAMKEHANAVSCIRMNKDDTQCVSSSADGTCIIWCLIKYTRKQIMFANTLFRCVCWRPDECQIITSGTDRKIGYWEVYDGSLIRELEGSRSGSVNGMDITADGDIFVTGGDDKIVKVWKYNEGYVTHVGLGHSMPITRLRISPDRQLITTVSEDGAIYFWKFP 2017
            V+  +G +  GL  HPDR+H+IY LGCTV+IE+L+++ Q FLQGHTNNV C+  S SG+Y+ASGQ+T+MG+KADI+LWDY  ++  +  +LHKVKV++LAFSPN+ YL SLGGQDDG VV+W++ K E ICGSPA   S+G    ++++N +DD+F+T G  TLRVW++D+ NRK+RPTEC LG +KR + C+ +S DDS F+CGTSSGDIL +N KS LLS   P+K  FSLGV ++  L  G+L+VG+GDG +   K               K + +  L G V+SI+LRGQGHQF+ GT  + IYRFS  +FK ELI T H  A+NDI +P    +LF TCS  D+RV+H+ + KELLRI +PNMTC   D  +DG +II+ W+D +IRAF PE+G LMY I +AH  GVTAIAATSDC+++VSGGGEGQVR+W I +                             +  +MKEH ++V+CI++  ++ +C+++S+DGTCIIW ++++TR Q++ +NTLFRCVC+ P+E Q +TSGTDRK+GYWEV+DGS IRELEGS+SG++NGMDI   G  FVTGGDDK+VKVW YNEG VTHVG+GHS  ITRL+I P  + I +VS DGAI  W +P
Sbjct:   18 VLSHSGHVPSGLISHPDREHLIYPLGCTVIIENLSSRKQQFLQGHTNNVSCVAASRSGRYLASGQVTYMGFKADILLWDYGRREACAKLTLHKVKVEALAFSPNDLYLVSLGGQDDGSVVVWNVAKREAICGSPASSLSSGHATTIIFTNNSDDIFMTGGNGTLRVWDVDLPNRKMRPTECQLGQMKRVVTCLQVSSDDSCFYCGTSSGDILTINTKSKLLSSFAPQKGKFSLGVTALRLLKTGELLVGSGDGKLALCKGPN-----------YKAAKTVQLQGSVTSISLRGQGHQFFVGTGGAQIYRFSYPEFKEELIATCHSEAINDIAFPFGTSELFATCSKNDIRVWHTATHKELLRITVPNMTCLAIDFMRDGKSIISAWNDGRIRAFMPESGRLMYCIENAHSMGVTAIAATSDCKRIVSGGGEGQVRIWEISK-------------------------ETQRLVQSMKEHKSSVTCIKLKGNNRECLTASSDGTCIIWDIVRFTRLQMVLSNTLFRCVCYHPEEFQFVTSGTDRKVGYWEVFDGSAIRELEGSKSGAINGMDICDQGAHFVTGGDDKLVKVWDYNEGEVTHVGIGHSGNITRLKICPLSKYIISVSTDGAILCWDYP 616          

Query:   83 NEINKLELINVIGFNGTILDGLHVHPDRQHIIYGLGCTVVIEDLNTKNQCFLQGHTNNVVCITVSNSGKYIASGQITHMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDGCVVIWSLTKMEPICGSPAQHKSAGITECLVYSNTNDDVFVTAGENTLRVWELDVENRKIRPTECSLGAIKRSIKCITISKDDSVFFCGTSSGDILGVNMKSCLLSCIGPEKETFSLGVLSIIRLINGDLIVGAGDGTICQVKVVEKKEGNKIMPKIVKTSNSCMLVGGVSSITLRGQGHQFYAGTEKSHIYRFSLGDFKSELINTAHYSAVNDIVYPNNCPKLFVTCSFQDVRVFHSDSQKELLRINIPNMTCYTCDIFKDGTAIITGWDDSKIRAFYPETGALMYTINDAHKKGVTAIAATSDCRKVVSGGGEGQVRVWRIEECKVSQANTIPHSHGNRKKSNVKSVVYVAHMETAMKEHANAVSCIRMNKDDTQCVSSSADGTCIIWCLIKYTRKQIMFANTLFRCVCWRPDECQIITSGTDRKIGYWEVYDGSLIRELEGSRSGSVNGMDITADGDIFVTGGDDKIVKVWKYNEGYVTHVGLGHSMPITRLRISPDRQLITTVSEDGAIYFWKFP 2017
            ++  K E    I  +  +  GL  HPDR+H+IY LGCTV+IE+L+++ Q FLQGHTNNV C+  S SG+Y+ASGQ+T+MG+KADI+LWDY  ++  +  +LHKVKV++LAFSPN+ YL SLGGQDDG VV+W++ K E ICGSPA   S+G    ++++N +DD+F+T G  TLRVW++D+ NRK+RPTEC LG +KR + C+ +S DDS F+CGTSSGDIL +N KS LLS   P+K  FSLGV ++  L  G+L+VG+GDG +   K               K + +  L G V+SI+LRGQGHQF+ GT  + IYRFS  +FK ELI T H  A+NDI +P    +LF TCS  D+RV+H+ + KELLRI +PNMTC   D  +DG +II+ W+D +IRAF PE+G LMY I +AH  GVTAIAATSDC+++VSGGGEGQVR+W I +                             +  +MKEH ++V+CI++  ++ +C+++S+DGTCIIW ++++TR Q++ +NTLFRCVC+ P+E Q +TSGTDRK+GYWEV+DGS IRELEGS+SG++NGMDI   G  FVTGGDDK+VKVW YNEG VTHVG+GHS  ITRL+I P  + I +VS DGAI  W +P
Sbjct:   28 HKARKAEPPTHIPISRHVPSGLISHPDREHLIYPLGCTVIIENLSSRKQQFLQGHTNNVSCVAASRSGRYLASGQVTYMGFKADILLWDYGRREACAKLTLHKVKVEALAFSPNDLYLVSLGGQDDGSVVVWNVAKREAICGSPASSLSSGHATTIIFTNNSDDIFMTGGNGTLRVWDVDLPNRKMRPTECQLGQMKRVVTCLQVSSDDSCFYCGTSSGDILTINTKSKLLSSFAPQKGKFSLGVTALRLLKTGELLVGSGDGKLALCKGPN-----------YKAAKTVQLQGSVTSISLRGQGHQFFVGTGGAQIYRFSYPEFKEELIATCHSEAINDIAFPFGTSELFATCSKNDIRVWHTATHKELLRITVPNMTCLAIDFMRDGKSIISAWNDGRIRAFMPESGRLMYCIENAHSMGVTAIAATSDCKRIVSGGGEGQVRIWEISK-------------------------ETQRLVQSMKEHKSSVTCIKLKGNNRECLTASSDGTCIIWDIVRFTRLQMVLSNTLFRCVCYHPEEFQFVTSGTDRKVGYWEVFDGSAIRELEGSKSGAINGMDICDQGAHFVTGGDDKLVKVWDYNEGEVTHVGIGHSGNITRLKICPLSKYIISVSTDGAILCWDYP 636          

Query:  113 VIGFNGTILDGLHVHPDRQHIIYGLGCTVVIEDLNTKNQCFLQGHTNNVVCITVSNSGKYIASGQITHMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDGCVVIWSLTKMEPICGSPAQHKSAGITECLVYSNTNDDVFVTAGENTLRVWELDVENRKIRPTECSLGAIKRSIKCITISKDDSVFFCGTSSGDILGVNMKSCLLSCIGPEKETFSLGVLSIIRLINGDLIVGAGDGTICQVKVVEKKEGNKIMPKIVKTSNSCMLVGGVSSITLRGQGHQFYAGTEKSHIYRFSLGDFKSELINTAHYSAVNDIVYPNNCPKLFVTCSFQDVRVFHSDSQKELLRINIPNMTCYTCDIFKDGTAIITGWDDSKIRAFYPETGALMYTINDAHKKGVTAIAATSDCRKVVSGGGEGQVRVWRIEECKVSQANTIPHSHGNRKKSNVKSVVYVAHMETAMKEHANAVSCIRMNKDDTQCVSSSADGTCIIWCLIKYTRKQIMFANTLFRCVCWRPDECQIITSGTDRKIGYWEVYDGSLIRELEGSRSGSVNGMDITADGDIFVTGGDDKIVKVWKYNEGYVTHVGLGHSMPITRLRISPDRQLITTVSEDGAIYFWKFP 2017
            V+  +G +  GL  HPDR+H+IY LGCTV+IE+L+++ Q FLQGHTNNV C+  S SG+Y+ASGQ+T+MG+KADI+LWDY  ++  +  +LHKVKV++LAFSPN+ YL SLGGQDDG VV+W++ K E ICGSPA   S+G    ++++N +DD+F+T G  TLRVW++D+ NRK+RPTEC LG +KR + C+   +DDS F+CGTSSGDIL +N KS LLS   P+K  FSLGV ++  L  G+L+VG+GDG +   K               K + +  L G V+SI+LRGQGHQF+ GT  + IYRFS  +FK ELI T H  A+NDI +P    +LF TCS  D+RV+H+ + KELLRI +PNMTC   D  +DG +II+ W+D +IRAF PE+G LMY I +AH  GVTAIAATSDC+++VSGGGEGQVR+W I +                             +  +MKEH ++V+CI++  ++ +C+++S+DGTCIIW ++++TR Q++ +NTLFRCVC+ P+E Q +TSGTDRK+GYWEV+DGS IRELEGS+SG++NGMDI   G  FVTGGDDK+VKVW YNEG VTHVG+GHS  ITRL+I P  + I +VS DGAI  W +P
Sbjct:   11 VLSHSGHVPSGLISHPDREHLIYPLGCTVIIENLSSRKQQFLQGHTNNVSCVAASRSGRYLASGQVTYMGFKADILLWDYGRREACAKLTLHKVKVEALAFSPNDLYLVSLGGQDDGSVVVWNVAKREAICGSPASSLSSGHATTIIFTNNSDDIFMTGGNGTLRVWDVDLPNRKMRPTECQLGQMKRVVTCL---QDDSCFYCGTSSGDILTINTKSKLLSSFAPQKGKFSLGVTALRLLKTGELLVGSGDGKLALCKGPN-----------YKAAKTVQLQGSVTSISLRGQGHQFFVGTGGAQIYRFSYPEFKEELIATCHSEAINDIAFPFGTSELFATCSKNDIRVWHTATHKELLRITVPNMTCLAIDFMRDGKSIISAWNDGRIRAFMPESGRLMYCIENAHSMGVTAIAATSDCKRIVSGGGEGQVRIWEISK-------------------------ETQRLVQSMKEHKSSVTCIKLKGNNRECLTASSDGTCIIWDIVRFTRLQMVLSNTLFRCVCYHPEEFQFVTSGTDRKVGYWEVFDGSAIRELEGSKSGAINGMDICDQGAHFVTGGDDKLVKVWDYNEGEVTHVGIGHSGNITRLKICPLSKYIISVSTDGAILCWDYP 606          

Query:   86 EINKLELINVIGFNGTILDGLHVHPDRQHIIYGLGCTVVIEDLNTKNQCFLQGHTNNVVCITVSNSGKYIASGQITHMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDGCVVIWSLTKMEPICGSPAQHKSAGITECLVYSNTNDDVFVTAGENTLRVWELDVENRKIRPTECSLGAIKRSIKCITISKDDSVFFCGTSSGDILGVNMKSCLLSCIGPEKETFSLGVLSIIRLINGDLIVGAGDGTICQVKVVEKKEGNKIMPKIVKTSNSCMLVGGVSSITLRGQGHQFYAGTEKSHIYRFSLGDFKSELINTAHYSAVNDIVYPNNCPKLFVTCSFQDVRVFHSDSQKELLRINIPNMTCYTCDIFKDGTAIITGWDDSKIRAFYPETGALMYTINDAHKKGVTAIAATSDCRKVVSGGGEGQVRVWRIEECKVSQANTIPHSHGNRKKSNVKSVVYVAHMETAMKEHANAVSCIRMNKDDTQCVSSSADGTCIIWCLIKYTRKQIMFANTLFRCVCWRPDECQIITSGTDRKIGYWEVYDGSLIRELEGSRSGSVNGMDITADGDIFVTGGDDKIVKVWKYNEGYVTHVGLGHSMPITRLRISPDRQLITTVSEDGAIYFWKFP 2017
            ++ +LEL  VIGFNG + +GL  HPD++H+IY LGCTV+I+ +NT  Q FL GH NNV C+T+S  G YIASGQ+T MG+KADI+LWD+  ++ ++  SLHK K+++LAFSPN+ YL SLGG DDG VV+WS+ K + ICGSPA   + G    +V+S   D++FVTAG  T+RVWELD+ NRKI PTEC  G +KR +    ++ DDS F+ GT++GDIL +N K+ LL+  GP K+ FSLGV ++  L  G L+VG+G G +   K    K   K+            L GG++SITLRG+GHQF+ GTE+SHIYR +  DFK  LI T H+ AV DIV+P    +LF TC+ +D+RV+H+ S++ELLRI +PNMTC+  D  +DG +II+ WDD KIRAF PE+G LMYTIN AH+ GVTAIA TSDC++++SGGGEG+VRVW++  C+  +                        +E A+KEH ++VSCIR+ K++ +CV++S DGTCIIW L++  R Q++ ANTLF+CVC+ P+E QIITSGTDRKI YWEV+DGS+IRELEGS SGS+NGMDIT +G  FVTGG D +VKVW YNEG VTHVG+GHS  I  +RISP  Q I +VS DGAI  WK+P
Sbjct:   10 DVAELELQAVIGFNGHVPNGLKCHPDQEHLIYPLGCTVLIQAINTNEQNFLHGHGNNVSCVTISKEGDYIASGQVTFMGFKADIILWDFKKRELIARLSLHKGKIEALAFSPNDLYLVSLGGPDDGSVVVWSIAKRDAICGSPAAGLNVGNATSVVFSRCRDEMFVTAGNGTIRVWELDLPNRKIWPTECQTGQMKRIVLSTGMADDDSFFYLGTTTGDILKMNPKTKLLADTGPVKDKFSLGVSALRCLKMGGLLVGSGAGLLIFCKSPSYKPIKKV-----------QLQGGITSITLRGEGHQFFVGTEESHIYRVNFTDFKETLIATCHFEAVQDIVFPFGTAELFATCAKKDIRVWHTMSKRELLRITVPNMTCHGIDFMRDGKSIISAWDDGKIRAFAPESGRLMYTINSAHRIGVTAIATTSDCKRIISGGGEGEVRVWQV-GCQTQK------------------------LEEALKEHKSSVSCIRVKKNNEECVTASTDGTCIIWDLVRLRRNQMILANTLFQCVCYHPEEFQIITSGTDRKIAYWEVFDGSVIRELEGSLSGSINGMDITQEGGHFVTGGHDHLVKVWDYNEGEVTHVGVGHSGNIMAMRISPGNQYIVSVSADGAILRWKYP 617          

Query:   86 EINKLELINVIGFNGTILDGLHVHPDRQHIIYGLGCTVVIEDLNTKNQCFLQGHTNNVVCITVSNSGKYIASGQITHMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDGCVVIWSLTKMEPICGSPAQHKSAGITECLVYSNTNDDVFVTAGENTLRVWELDVENRKIRPTECSLGAIKRSIKCITISKDDSVFFCGTSSGDILGVNMKSCLLSCIGPEKETFSLGVLSIIRLINGDLIVGAGDGTICQVKVVEKKEGNKIMPKIVKTSNSCMLVGGVSSITLRGQGHQFYAGTEKSHIYRFSLGDFKSELINTAHYSAVNDIVYP 1114
            ++ +LEL  VIGFNG + +GL  HPD++H+IY LGCTV+I+ +NT  Q FL GH NNV C+T+S  G YIASGQ+T MG+KADI+LWD+  ++ ++  SLHK K+++LAFSPN+ YL SLGG DDG VV+WS+ K + ICGSPA   + G    +V+S   D++FVTAG  T+RVWELD+ NRKI PTEC  G +KR +    ++ DDS F+ GT++GDIL +N K+ LL+  GP K+ FSLGV ++  L  G L+VG+G G +   K    K   K+            L GG++SITLRG+GHQF+ GTE+SHIYR +  DFK  LI T H+ AV DIV+P
Sbjct:   10 DVAELELQAVIGFNGHVPNGLKCHPDQEHLIYPLGCTVLIQAINTNEQNFLHGHGNNVSCVTISKEGDYIASGQVTFMGFKADIILWDFKKRELIARLSLHKGKIEALAFSPNDLYLVSLGGPDDGSVVVWSIAKRDAICGSPAAGLNVGNATSVVFSRCRDEMFVTAGNGTIRVWELDLPNRKIWPTECQTGQMKRIVLSTGMADDDSFFYLGTTTGDILKMNPKTKLLADTGPVKDKFSLGVSALRCLKMGGLLVGSGAGLLIFCKSPSYKPIKKV-----------QLQGGITSITLRGEGHQFFVGTEESHIYRVNFTDFKETLIATCHFEAVQDIVFP 341          

Query:   92 NKLELINVIGFNGTILDGLHVHPDRQHIIYGLGCTVVIEDLNTKNQCFLQGHTNNVVCITVSNSGKYIASGQIT-HMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDGCVVIWSLTKMEPICGSPAQHKSAGITECLVYSNTNDDVFVTAGENTLRVWELDVE--------NRKIRPTECSLGAIKRSIKCITISKDDSVFFCGTSSGD--ILGVNMKSCLLSCIGPEKETFSLGVL--SIIRLINGDLIVGAGDGTICQVKVVE--KKEGNKIMPKIVKTSNSCMLVGGVSSITLRGQGHQFYAGTEKSHIYRFSLGDFKSELINTAHYSAVNDIVYPNNCPKLFVTCSFQDVRVFHSDSQKELLRINIPNMTCY-------TCDIFKDGTAIITGWDDSKIRAFYPETGALMYTINDAHKKGVTAIAATSDCRKVVSGGGEGQVRV 1420
             +L L  ++G+NG     +   PD     Y  G  VV+EDL++  Q    GH+  +  + ++  G+ +AS     +   +  I +WD     C    S H   VQ+LAFSP++++L +LG   D  + +WS+   E +  +       G+     ++  + +  +  G N +  W L           +R+  P E  LGA + +  C   S    + +CG+SSG   +       C L+    E +   +GVL  S  RLI+G          +  V VV   +++G+      V       L G V S +          GT    I+  S  +  S  + + H + VN++V+               VRV+   S + +++  + N +C        +C++  +   ++ G+ D  +R F     A+   ++  H+  +TAIA ++D + ++SG  +G V +
Sbjct: 1248 ERLRLKAIVGYNGNGRANMVWRPDTGFFAYTCGRLVVVEDLHSGTQRHWLGHSQEISTLALNQDGQILASASCCGNTAARCQIRIWDVPKGLCRHLLSHHDTAVQALAFSPDDEFLVTLGDYADRNLALWSMATYELLSSTRLLEPVHGV----AFNPWDANELICVGTNAITFWLLQHHGADTCFQVHREPIPEE--LGASELTSLCYGASP---LLYCGSSSGQVCVWDTGTGHCFLAW---EADDGEIGVLLCSGSRLISGS---NTKRLRLWAVGVVPELRRKGSSARSSSVFMERELTLDGAVVSASFDSGMDMGVVGTTAGTIWYISWTEGTSTRLISGHRTKVNEVVFSPGESHCATCGEDGSVRVWSLASMELVIQFQVLNQSCLCLAWTPPSCEL-PEQQQVVAGYSDGTLRVFSISRTAMELKMH-PHRTALTAIAFSTDGQTILSGDKDGLVAI 1695          

Query:   98 LELINVIGFNGTILDGLHVHPDRQHIIYGLGCTVVIEDLNTKNQCFLQGHTNNVVCITVSNSGKYIASGQITHMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDGCVVIWSLTKMEPICGSPAQHKSAGITECLVYSNTNDDV------------FVTAGENTLRVWELDVENRKIRPTECSLG----------AIKRSIKCITISKDDSVFFCGTSSGDILGVNMKSC-------LLSCIGP-----EKETFSLG---VLSIIRLINGDLIVGAGDGTICQVKVVEKKEGNKIMPKIVKTSNSCMLV-----GGVSSITLRGQGHQFYAGTEKSHIYRFSLGDFKSELINTAHYSAVNDIVYPNNCPKLFVTCSFQDVRVFHSDSQKELLRINIPNMTCYTCDIFKDGTAIITGWDDSKIRAFYPETGALMYTINDAHKKGVTAIAATSDCRKVVSGGGEGQVRVWRIEECKVSQ-------ANTIPHSHGNRKKSNVKSVVYVAHMETAMKEHANAVSCIRMNKDDTQCVSSSADGTCIIWCLIKYTRKQIMFANTL--FRCVCWRP-DECQIITSGTDRKIGYWEVYDGSLIRELEGSRSGSVNGMDITADGDIFVTGGDDKIVKVWKY--NEGYVTHVGLGHSMPITRLRISPDRQLITTVSEDGAIYFW 2008
            L L  VIGF G          D   ++Y     +++  ++T  Q F  GHT+ V  + ++ S   +AS Q+      + + LWD+ T  C+S F      + SL+FS +   L  +G    G  V+        +  S  Q    G    L   +T+ D+              + G  ++R+W L      +R     LG          A  +++         ++F C + SG IL ++ +         LL    P     EK+ FS+G    +S + +      VG+ DG +                ++     S +L+     G VSS++    G +  + T   H+    +   +  ++  +H + V  +    N  ++        VR++   + ++L   +    T               G+    +R+F  E+  ++   +  H+  +T++  T D R + S   +G +  +    C  SQ       AN +      R   N+ +V              +  SC       ++C+ +  +   +   L        + +N L     +C+ P +   ++ S +  K+   +   G  +REL   RS +   + ++ D  + +    D+ + VW Y         V +GHS P+  +  +PD+  + +V +  AI+ W
Sbjct:  439 LRLKGVIGFGGHSTQWALWTKDGVAVVYPCHAVIIVLQIDTGQQRFFLGHTDKVSALALNGSDTLLASAQVQP---PSMVRLWDFQTGSCLSLFRSPLHTICSLSFSGSGALLCGVGKDRHGRTVV--------VAWSTEQAGLGGEVVVLAKVHTDFDIRAFQVAFFDETRMASCGRGSVRLWRL--RGGVLRSCAVDLGEYCSLELTDLAFAQALDGHCAPSAGTLFVC-SHSGHILEIDHQRMSVQHVRRLLPARSPGAPLAEKQNFSVGSGIAISSLSVSTATCAVGSEDGYL----------------RLWPLDFSSVLLEAEHDGPVSSVSFSPDGLRVLSTTTSGHLGFLDVPSREYTVLARSHMAPVLALSTEPNRGQMATVSLDHTVRIWDLATLQQLYDFSSSEDTPCAVAFHPTMPNFFCGFSSGAVRSFSLESSGVLVE-HTRHRGAITSLVITLDGRFLFSSCSQGSLVQY---SCADSQCCVLRVAANMV--CQDGRPNPNILAV--------------SGDSCRLAFVGPSKCMVTIVESASLDELLRVDVSTLNLASNHLDWAVAICFSPGNSGHLLVSTSSNKVVVLDAVSGHTLRELSSVRSRACCSLALSEDAHLLL-AATDRTITVWDYPTQANPSCQVYIGHSEPVHAVAFTPDQLQVISVGD--AIFLW 1076          

Query:   92 NKLELINVIGFNGTILDGLHVHPDRQHIIYGLGCTVVIEDLNTKNQCFLQGHTNNVVCITVSNSGKYIASGQIT-HMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDGCVVIWSLTKMEPICGSPAQHKSAGITECLVYSNTNDDVFVTAGENTLRVWELDVE--------NRKIRPTECSLGAIKRSIKCITISKDDSVFFCGTSSGD--ILGVNMKSCLLSCIGPEKETFSLGVL--SIIRLINGDLIVGAGDGTICQVKVVE--KKEGNKIMPKIVKTSNSCMLVGGVSSITLRGQGHQFYAGTEKSHIYRFSLGDFKSELINTAHYSAVNDIVYPNNCPKLFVTCSFQDVRVFHSDSQKELLRINIPNMTCY-------TCDIFKDGTAIITGWDDSKIRAFYPETGALMYTINDAHKKGVTAIAATSDCRKVVSGGGEGQVRV 1420
             +L L  ++G+NG     +   PD     Y  G  VV+EDL++  Q    GH+  +  + ++  G+ +AS     +   +  I +WD     C    S H   VQ+LAFSP++++L +LG   D  + +WS+   E +  +       G+     ++  + +  +  G N +  W L           +R+  P E  LGA + +  C   S    + +CG+SSG   +       C L+    E +   +GVL  S  RLI+G          +  V VV   +++G+      V       L G V S +          GT    I+  S  +  S  + + H + VN++V+               VRV+   S + +++  + N +C        +C++  +   ++ G+ D  +R F     A+   ++  H+  +TAIA ++D + ++SG  +G V +
Sbjct: 1230 ERLRLKAIVGYNGNGRANMVWRPDTGFFAYTCGRLVVVEDLHSGTQRHWLGHSQEISTLALNQDGQILASASCCGNTAARCQIRIWDVPKGLCRHLLSHHDTAVQALAFSPDDEFLVTLGDYADRNLALWSMATYELLSSTRLLEPVHGV----AFNPWDANELICVGTNAITFWLLQHHGADTCFQVHREPIPEE--LGASELTSLCYGASP---LLYCGSSSGQVCVWDTGTGHCFLAW---EADDGEIGVLLCSGSRLISGS---NTKRLRLWAVGVVPELRRKGSSARSSSVFMERELTLDGAVVSASFDSGMDMGVVGTTAGTIWYISWTEGTSTRLISGHRTKVNEVVFSPGESHCATCGEDGSVRVWSLASMELVIQFQVLNQSCLCLAWTPPSCEL-PEQQQVVAGYSDGTLRVFSISRTAMELKMH-PHRTALTAIAFSTDGQTILSGDKDGLVAI 1677          

Query:   98 LELINVIGFNGTILDGLHVHPDRQHIIYGLGCTVVIEDLNTKNQCFLQGHTNNVVCITVSNSGKYIASGQITHMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDGCVVIWSLTKMEPICGSPAQHKSAGITECLVYSNTNDDV------------FVTAGENTLRVWELDVENRKIRPTECSLG----------AIKRSIKCITISKDDSVFFCGTSSGDILGVNMKSC-------LLSCIGP-----EKETFSLG---VLSIIRLINGDLIVGAGDGTICQVKVVEKKEGNKIMPKIVKTSNSCMLV-----GGVSSITLRGQGHQFYAGTEKSHIYRFSLGDFKSELINTAHYSAVNDIVYPNNCPKLFVTCSFQDVRVFHSDSQKELLRINIPNMTCYTCDIFKDGTAIITGWDDSKIRAFYPETGALMYTINDAHKKGVTAIAATSDCRKVVSGGGEGQVRVWRIEECKVSQ-------ANTIPHSHGNRKKSNVKSV---------VYVAHMETAMKEHANAVSCIRMNKDDTQCVSSSADGTCIIWCLIKYTRKQIMFANTLFRCVCWRP-DECQIITSGTDRKIGYWEVYDGSLIRELEGSRSGSVNGMDITADGDIFVTGGDDKIVKVWKY--NEGYVTHVGLGHSMPITRLRISPDRQLITTVSEDGAIYFW 2008
            L L  VIGF G          D   ++Y     +++  ++T  Q F  GHT+ V  + ++ S   +AS Q+      + + LWD+ T  C+S F      + SL+FS +   L  +G    G  V+        +  S  Q    G    L   +T+ D+              + G  ++R+W L      +R     LG          A  +++         ++F C + SG IL ++ +         LL    P     EK+ FS+G    +S + +      VG+ DG +                ++     S +L+     G VSS++    G +  + T   H+    +   +  ++  +H + V  +    N  ++        VR++   + ++L   +    T               G+    +R+F  E+  ++   +  H+  +T++  T D R + S   +G +  +    C  SQ       AN +      R   N+ +V         V  +     + E A+    +R++       S+  D     W +                 +C+ P +   ++ S +  K+   +   G  +REL   RS +   + ++ D  + +    D+ + VW Y         V +GHS P+  +  +PD+  + +V +  AI+ W
Sbjct:  421 LRLKGVIGFGGHSTQWALWTKDGVAVVYPCHAVIIVLQIDTGQQRFFLGHTDKVSALALNGSDTLLASAQVQP---PSMVRLWDFQTGSCLSLFRSPLHTICSLSFSGSGALLCGVGKDRHGRTVV--------VAWSTEQAGLGGEVVVLAKVHTDFDIRAFQVAFFDETRMASCGRGSVRLWRL--RGGVLRSCAVDLGEYCSLELTDLAFAQALDGHCAPSAGTLFVC-SHSGHILEIDHQRMSVQHVRRLLPARSPGAPLAEKQNFSVGSGIAISSLSVSTATCAVGSEDGYL----------------RLWPLDFSSVLLEAEHDGPVSSVSFSPDGLRVLSTTTSGHLGFLDVPSREYTVLARSHMAPVLALSTEPNRGQMATVSLDHTVRIWDLATLQQLYDFSSSEDTPCAVAFHPTMPNFFCGFSSGAVRSFSLESSGVLVE-HTRHRGAITSLVITLDGRFLFSSCSQGSLVQY---SCADSQCCVLRVAANMV--CQDGRPNPNILAVSGDSCRLAFVGPSKCMVTIVESASLDELLRVDVSTLNLASNHLD-----WAV----------------AICFSPGNSGHLLVSTSSNKVVVLDAVSGHTLRELSSVRSRACCSLALSEDAHLLL-AATDRTITVWDYPTQANPSCQVYIGHSEPVHAVAFTPDQLQVISVGD--AIFLW 1058          

Query:   92 NKLELINVIGFNGTILDGLHVHPDRQHIIYGLGCTVVI-EDLNTKNQCFLQGHTNNVVCITVSNSGKYIASGQITHMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDGCVVIWSLTKMEPICGSPAQHKSAGITECLVYSNTNDDVFVTAGENTLRVWEL-DVENRKIRPTECSLGA----------IKRSIKCITISKDDSVFFCGTSSGDILGVNMKSCLLSCIG-PEKETFSLGVLSIIRLINGDLIVGAGDGTI 877
            +K+ L  V+G   +   GL   P    + Y  GC VV+      K    L      +  +  S  GKY+ +G+  HM     + +WD   +  V+    HK  V  +AFSP+ KY+ S+G Q D  V +W+  K   +  +    +   ++      + +   FVTAG   ++ W L D +  K+  T   LG           +   + C    K DS  FC TSSG +   + +  L   +     ++F+  V   I +    +  G  DGT+
Sbjct:   38 SKVTLEKVLGVTVSGGRGLACDPRSGLVAYPAGCVVVLFNPRKHKQHHILNSSRKTITALAFSPDGKYLVTGESGHM---PAVRVWDVAERSQVAELQEHKYGVACVAFSPSAKYIVSVGYQHDMIVNVWAWKKNIVVASNKVSSRVTAVS-----FSEDCSYFVTAGNRHIKFWYLDDSKTSKVNATVPLLGRSGLLGELRNNLFTDVACGRGEKADST-FCITSSGLLCEFSDRRLLDKWVELRNTDSFTTTVAHCISVTQEYIFCGCADGTV 303          

Query:   86 EINKLELINVIGFNGTILDGLHVHPDRQHIIYGLGCTVVIEDLNTKNQCFLQGHTNNVVCITVSNSGKYIASGQITHMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDGCVVIWSLTKMEPICGSPAQHKSAGITECLVYSNTNDDVFVTAGENTLRVWELDVENRKIRPTECSLGAIKRSIKCITISKDDSVFFCGTSSGDILGVNMKSCLLSCIGPEKETFSLGVLSIIRLINGDLIVGAGDGTICQVKVVEKKEGNKIMPKIVKTSNSCMLVGGVSSITLRGQGHQFYAGTEKSHIYRFSLGDFKSELINTAHYSAVNDIVYPNNCPKLFVTCSFQDVRVFHSDSQKELLRINIPNMTCYTCDIFKDGTAIITGWDDSKIRAFYPETGALMYTINDAHKKGVTAIAATSDCRKVVSGGGEGQVRVWRIEECKVSQANTIPHSHGNRKKSNVKSVVYVAHMETAMKEHANAVSCIRMNKDDTQCVSSSADGTCIIWCLIKYTRKQIMFANTLFRCVCWRPDECQIITSGTDRKIGYWEVYDGSLIRELEGSRSGSVNGMDITADGDIFVTGGDDKIVKVWKYNEGYVTHVGLGHSMPITRLRISPDRQLITTVSEDGAIYFWKFP 2017
            ++ +LEL  VIGFNG +  GL  HPD++H+IY LGCTV+I+ +NTK Q FLQGH NNV C+ +S SG+YIASGQ+T MG+KADI+LWDY  ++ ++  SLHK K+++LAFSPN+ YL SLGG DDG VV+WS+ K + ICGSPA   + G    +++S   D++F+TAG  T+RVWELD+ NRKI PTEC  G +KR +  I +  DDS F+ GT++GDIL +N ++ LL+ +GP K+ FSLGV +I  L  G L+VG+G G +    V  K  G K + KI        L GG++SITLRG+GHQF  GTE+SHIYR S  DFK  LI T H+ AV DIV+P    +LF TC+ +D+RV+H+ S +ELLRI +PNMTC+  D  +DG +II+ W+D KIRAF PETG LMY IN+AH+ GVTAIA TSDC++V+SGGGEG+VRVW+I  C+  +                        +E A+KEH ++VSCIR+ +++ +CV++S DGTCIIW L++  R Q++ ANTLF+CVC+ P+E QIITSGTDRKI YWEV+DG++IRELEGS SGS+NGMDIT +G  FVTGG+D +VKVW YNEG VTHVG+GHS  ITR+RISP  Q I +VS DGAI  WK+P
Sbjct:   10 QVAELELDAVIGFNGHVPTGLKCHPDQEHMIYPLGCTVLIQAINTKEQNFLQGHGNNVSCLAISRSGEYIASGQVTFMGFKADIILWDYKNRELLARLSLHKGKIEALAFSPNDLYLVSLGGPDDGSVVVWSIAKRDAICGSPAAGLNVGNATNVIFSRCRDEMFMTAGNGTIRVWELDLPNRKIWPTECQTGQLKRIVMSIGVDDDDSFFYLGTTTGDILKMNPRTKLLTDVGPAKDKFSLGVSAIRCLKMGGLLVGSGAGLL----VFCKSPGYKPIKKI-------QLQGGITSITLRGEGHQFLVGTEESHIYRVSFTDFKETLIATCHFDAVEDIVFPFGTAELFATCAKKDIRVWHTSSNRELLRITVPNMTCHGIDFMRDGKSIISAWNDGKIRAFAPETGRLMYVINNAHRIGVTAIATTSDCKRVISGGGEGEVRVWQI-GCQTQK------------------------LEEALKEHKSSVSCIRVKRNNEECVTASTDGTCIIWDLVRLRRNQMILANTLFQCVCYHPEEFQIITSGTDRKIAYWEVFDGTVIRELEGSLSGSINGMDITQEGVHFVTGGNDHLVKVWDYNEGEVTHVGVGHSGNITRIRISPGNQYIVSVSADGAILRWKYP 617          

Query:   86 EINKLELINVIGFNGTILDGLHVHPDRQHIIYGLGCTVVIEDLNTKNQCFLQGHTNNVVCITVSNSGKYIASGQITHMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDGCVVIWSLTKMEPICGSPAQHKSAGITECLVYSNTNDDVFVTAGENTLRVWELDVENRKIRPTECSLGAIKRSIKCITISKDDSVFFCGTSSGDILGVNMKSCLLSCIGPEKETFSLGVLSIIRLINGDLIVGAGDGTICQVKVVEKKEGNKIMPKIVKTSNSCMLVGGVSSITLRGQGHQFYAGTEKSHIYRFSLGDFKSELINTAHYSAVNDIVYPNNCPKLFVTCSFQDVRVFHSDSQKELLRINIPNMTCYTCDIFKDGTAIITGWDDSKIRAFYPETGALMYTINDAHKKGVTAIAATSDCRKVVSGGGEGQVRVWRIEECKVSQANTIPHSHGNRKKSNVKSVVYVAHMETAMKEHANAVSCIRMNKDDTQCVSSSADGTCIIWCLIKYTRKQIMFANTLFRCVCWRPDECQIITSGTDRKIGYWEVYDGSLIRELEGSRSGSVNGMDITADGDIFVTGGDDKIVKVWKYNEGYVTHVGLGHSMPITRLRISPDRQLITTVSEDGAIYFWKFP 2017
            ++ +LEL  VIGFNG + +GL  HPD++H+IY LGCTV+I+ +NT  Q FL GH NNV C+T+S  G YIASGQ+T MG+KADI+LWD+  ++ ++  SLHK K+++LAFSPN+ YL SLGG DDG VV+WS+ K + ICGSPA   + G    +V+S   D++FVTAG  T+RVWELD+ NRKI PTEC  G +KR +    ++ DDS F+ GT++GDIL +N K+ LL+  GP K+ FSLGV ++  L  G L+VG+G G +   K    K   K+            L GG++SITLRG+GHQF+ GTE+SHIYR +  DFK  LI T H+ AV DIV+P    +LF TC+ +D+RV+H+ S++ELLRI +PNMTC+  D  +DG +II+ WDD KIRAF PE+G LMYTIN AH+ GVTAIA TSDC++++SGGGEG+VRVW++  C+  +                        +E A+KEH ++VSCIR+ K++ +CV++S DGTCIIW L++  R Q++ ANTLF+CVC+ P+E QIITSGTDRKI YWEV+DGS+IRELEGS SGS+NGMDIT +G  FVTGG D +VKVW YNEG VTHVG+GHS  I  +RISP  Q I +VS DGAI  WK+P
Sbjct:   10 DVAELELQAVIGFNGHVPNGLKCHPDQEHLIYPLGCTVLIQAINTNEQNFLHGHGNNVSCVTISKEGDYIASGQVTFMGFKADIILWDFKKRELIARLSLHKGKIEALAFSPNDLYLVSLGGPDDGSVVVWSIAKRDAICGSPAAGLNVGNATSVVFSRCRDEMFVTAGNGTIRVWELDLPNRKIWPTECQTGQMKRIVLSTGMADDDSFFYLGTTTGDILKMNPKTKLLADTGPVKDKFSLGVSALRCLKMGGLLVGSGAGLLIFCKSPSYKPIKKV-----------QLQGGITSITLRGEGHQFFVGTEESHIYRVNFTDFKETLIATCHFEAVQDIVFPFGTAELFATCAKKDIRVWHTMSKRELLRITVPNMTCHGIDFMRDGKSIISAWDDGKIRAFAPESGRLMYTINSAHRIGVTAIATTSDCKRIISGGGEGEVRVWQV-GCQTQK------------------------LEEALKEHKSSVSCIRVKKNNEECVTASTDGTCIIWDLVRLRRNQMILANTLFQCVCYHPEEFQIITSGTDRKIAYWEVFDGSVIRELEGSLSGSINGMDITQEGGHFVTGGHDHLVKVWDYNEGEVTHVGVGHSGNIMAMRISPGNQYIVSVSADGAILRWKYP 617          

Query:   86 EINKLELINVIGFNGTILDGLHVHPDRQHIIYGLGCTVVIEDLNTKNQCFLQGHTNNVVCITVSNSGKYIASGQITHMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDGCVVIWSLTKMEPICGSPAQHKSAGITECLVYSNTNDDVFVTAGENTLRVWELDVENRKIRPTECSLGAIKRSIKCITISKDDSVFFCGTSSGDILGVNMKSCLLSCIGPEKETFSLGVLSIIRLINGDLIVGAGDGTICQVKVVEKKEGNKIMPKIVKTSNSCMLVGGVSSITLRGQGHQFYAGTEKSHIYRFSLGDFKSELINTAHYSAVNDIVYPNNCPKLFVTCSFQDVRVFHSDSQKELLRINIPNMTCYTCDIFKDGTAIITGWDDSKIRAFYPETGALMYTINDAHKKGVTAIAATSDCRKVVSGGGEGQVRVWRIEECKVSQANTIPHSHGNRKKSNVKSVVYVAHMETAMKEHANAVSCIRMNKDDTQCVSSSADGTCIIWCLIKYTRKQIMFANTLFRCVCWRPDECQIITSGTDRKIGYWEVYDGSLIRELEGSRSGSVNGMDITADGDIFVTGGDDKIVKVWKYNEGYVTHVGLGHSMPITRLRISPDRQLITTVSEDGAIYFWKFP 2017
            ++ +LEL  VIGFNG +  GL  HPD++H+I+ LGCT++I+ +NT+ Q FLQGH NNV C+ +S SG+YIASGQ+T MG+KADI+LWDY  ++ ++  SLHK K+++LAFSPN+ YL SLGG DDG VV+WS+ K + ICGSPA   + G    +++S   D++FVTAG  T+RVWELD+ NRKI PTEC  G +KR +  I ++ DDS F+ GT++GDIL +N ++ LL+  GP K+ FSLGV +I  L  G L+VG+G G +   K    K   KI  +           GG++SITLRG+GHQF+ GTE+SHIYR S  DFK  LI T H+ AV DIV+P    +LF TC+ +D+RV+H+ S                                                 N AH+ GVTAIA TSDC++V+SGGGEG+VRVW+I  C+  +                        +E A+KEH ++VSCIR+ K++ +CV++S DGTCIIW L++  R Q++ ANTLF+CVC+ P+E QIITSGTDRKI YWEV+DG++IRELEGS SGS+NGMDIT +G  FVTGG+D +VKVW YNEG VTHVG+GHS  ITR+RISP  Q I +VS DGAI  WK+P
Sbjct:   10 QVAELELDAVIGFNGHVPTGLKCHPDQEHLIFPLGCTILIQAINTQEQNFLQGHGNNVSCLAISRSGRYIASGQVTFMGFKADIILWDYKKRELLARLSLHKGKIEALAFSPNDLYLVSLGGPDDGSVVVWSIAKRDAICGSPAAGLNVGNATNVIFSRCRDEMFVTAGNGTIRVWELDLPNRKIWPTECQTGQMKRIVMSIGMADDDSFFYLGTTTGDILKMNPRTKLLTDAGPAKDKFSLGVSAIRCLKMGGLLVGSGAGLLVFCKSPSYKPIKKIQSQ-----------GGITSITLRGEGHQFFVGTEESHIYRVSFTDFKETLIATCHFEAVEDIVFPFGTAELFATCAKKDIRVWHTSS-------------------------------------------------NSAHRIGVTAIATTSDCKRVISGGGEGEVRVWQI-GCQTQK------------------------LEEALKEHKSSVSCIRVKKNNEECVTASTDGTCIIWDLVRLRRNQMILANTLFQCVCYHPEEFQIITSGTDRKIAYWEVFDGTVIRELEGSLSGSINGMDITQEGVHFVTGGNDHLVKVWDYNEGEVTHVGVGHSGNITRIRISPGNQYIVSVSADGAILRWKYP 568          

Query:   98 LELINVIGFNGTILDGLHVHPDRQHIIYGLGCTVVIED-LNTKNQCFLQGHTNNVVCITVSNSGKYIASGQITHMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDGCVVIWSLTKMEPICGSPAQHKSAGITECLVYSNTNDDVFVTAGENTLRVWELDVENRKIRPTECSLGAIKRSIKCITISKDDSVFFCGTSSGDILGVNMKSCLLSCIGPEKETFSLGVLSIIRLINGDLIVGAGDGTICQVKVVEKKEGNKIMPKIVKTSNSCMLVGGVSSITL---RGQGHQFYAGTEKSHIYRFSLGDFKSELINTAHYSAVNDIVYPNNCPKLFVTCSFQDVRVFHSDSQKELLRINIPNMTCYTCDIFKDGTAIITGWDDSKIRAFYPETGALMYTINDAHKKGVTAIAATSDCRKVVSGGGEGQVRVWRIEECKVSQANTIPHSHGNRKKSNVKSVVYVAHMETAMKEHANAVSCIRMNKDDTQCVSSSADGTCIIWCLIKYTRKQIMFANTLFRCVCWRPDECQIITSGTDRKIGYWEVYDGSLIRELEGSRSGSVNGMDITADGDIFVTGGDDKIVKVWKYNEGYVTHVGLGHSMPITRLRISPDRQLITTVSEDGAIYFWKF 2014
            L L +VIGF G I +GL  HPD + IIY LG T+V+ D  + ++Q FLQGH++ V C+ +S SG+Y+ASGQIT+MG+ ADI++WD  +KQ +   +LHKVKVQ+L FS +E++LASLGGQDD  +V+W +     ICGSP    +   T C+ + N + D  +TAG   + VW  D  N K+RPT+ +LG +KR  K + +  +D   +CGT++GD+L + ++  L    GP K    +GV +   +  GD++VG GDG++  ++ +    G K+              G ++SI L     +G  F+ GT   +IY+ +    K EL+ TAH   +N + +PN   ++F TC    +R++H  + +ELLRI +PN+ C+      DG+AI++GW D KIRAF P++G +++TINDAH+K VTAIA+T+D  +++SGG EG VRVWRI   + SQ                        +E +MK+H   V+CIR+     +CVS+S+DG+CI+W L  + R+  +FANT F+ V + PDE Q++T+GTDRK+ YW+ YDG+ IR ++GS    VN + +  DG+  V+GG DK+VK+W Y+EG+   VG+ HS  IT + ++PD+Q I +V  +G I+ W +
Sbjct:    5 LVLNSVIGFGGAIENGLIAHPDGRTIIYPLGSTIVLRDRADPRSQEFLQGHSDKVSCLALSRSGRYLASGQITYMGFTADIIIWDLESKQLIHRMALHKVKVQALDFSCDERFLASLGGQDDNALVLWDVASGNAICGSPC---NTNFTNCVKFFNNSPDKLITAGNFNMNVWTYDAGNNKLRPTDATLGTLKRVFKSVVVDANDEYAYCGTTTGDVLQIALERVLFKNTGPAKGNVQMGVTATCEVPTGDILVGGGDGSLQLLRKMPALAGTKVE-------------GAITSIALADMNARGFTFFVGTAMCNIYKPATSRLKEELVQTAHNDKINGMAFPNEYSEVFATCGTGFIRLWHLTTCRELLRIAVPNLECFCIAFTTDGSAILSGWSDGKIRAFGPQSGKIIFTINDAHQKAVTAIASTADSSRILSGGEEGMVRVWRIG--RTSQT-----------------------LEASMKDHKGPVNCIRIKGSGDECVSASSDGSCILWDLHTFKRRTSLFANTFFKSVVYHPDESQLVTAGTDRKVTYWDAYDGNAIRIIDGSDLDEVNALAVDRDGEALVSGGGDKLVKLWGYDEGHCYFVGVAHSGAITAVGVTPDKQRIVSVGTEGGIFIWDY 606          

Query:   92 NKLELINVIGFNGTILDGLHVHPDRQHIIYGLGCTVVIEDLNTKNQCFLQGHTNNVVCITVSNSGKYIASGQIT-HMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDGCVVIWSLTKMEPICGSPAQHKSAGITECLVYSNTNDDVFVTAGENTLRVWELDVE--------NRKIRPTECSLGAIKRSIKCITISKDDSVFFCGTSSGD--ILGVNMKSCLLSCIGPEKETFSLGVL--SIIRLINGDLIVGAGDGTICQVKVVE--KKEGNKIMPKIVKTSNSCMLVGGVSSITLRGQGHQFYAGTEKSHIYRFSLGDFKSELINTAHYSAVNDIVYPNNCPKLFVTCSFQDVRVFHSDSQKELLRINIPNMTCY-------TCDIFKDGTAIITGWDDSKIRAFYPETGALMYTINDAHKKGVTAIAATSDCRKVVSGGGEGQVRV 1420
             +L L  ++G+NG     +   PD     Y  G  VV+EDL++  Q    GH+  +  + ++  G+ +AS     +   +  I +WD     C    S H   VQ+LAFSP++++L +LG   D  + +WS+   E +  +       G+     ++  + +  +  G N +  W L           +R+  P E  LGA + +  C   S    + +CG+SSG   +       C L+    E +   +GVL  S  RLI+G          +  V VV   +++G+      V       L G V S +          GT    I+  S  +  S  + + H + VN++V+               VRV+   S + +++  + N +C        +C++  +   ++ G+ D  +R F     A+   ++  H+  +TAIA ++D + ++SG  +G V +
Sbjct: 1230 ERLRLKAIVGYNGNGRANMVWRPDTGFFAYTCGRLVVVEDLHSGTQRHWLGHSQEISTLALNQDGQILASASCCGNTAARCQIRIWDVPKGLCRHLLSHHDTAVQALAFSPDDEFLVTLGDYADRNLALWSMATYELLSSTRLLEPVHGV----AFNPWDANELICVGTNAITFWLLQHHGADTCFQVHREPIPEE--LGASELTSLCYGASP---LLYCGSSSGQVCVWDTGTGHCFLAW---EADDGEIGVLLCSGSRLISGS---NTKRLRLWAVGVVPELRRKGSSARSSSVFMERELTLDGAVVSASFDSGMDMGVVGTTAGTIWYISWTEGTSTRLISGHRTKVNEVVFSPGESHCATCGEDGSVRVWSLASMELVIQFQVLNQSCLCLAWTPPSCEL-PEQQQVVAGYSDGTLRVFSISRTAMELKMH-PHRTALTAIAFSTDGQTILSGDKDGLVAI 1677          

Query:   98 LELINVIGFNGTILDGLHVHPDRQHIIYGLGCTVVIEDLNTKNQCFLQGHTNNVVCITVSNSGKYIASGQITHMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDGCVVIWSLTKMEPICGSPAQHKSAGITECLVYSNTNDDV------------FVTAGENTLRVWELDVENRKIRPTECSLG----------AIKRSIKCITISKDDSVFFCGTSSGDILGVNMKSC-------LLSCIGP-----EKETFSLG---VLSIIRLINGDLIVGAGDGTICQVKVVEKKEGNKIMPKIVKTSNSCMLV-----GGVSSITLRGQGHQFYAGTEKSHIYRFSLGDFKSELINTAHYSAVNDIVYPNNCPKLFVTCSFQDVRVFHSDSQKELLRINIPNMTCYTCDIFKDGTAIITGWDDSKIRAFYPETGALMYTINDAHKKGVTAIAATSDCRKVVSGGGEGQVRVWRIEECKVSQ-------ANTIPHSHGNRKKSNVKSV---------VYVAHMETAMKEHANAVSCIRMNKDDTQCVSSSADGTCIIWCLIKYTRKQIMFANTLFRCVCWRP-DECQIITSGTDRKIGYWEVYDGSLIRELEGSRSGSVNGMDITADGDIFVTGGDDKIVKVWKY--NEGYVTHVGLGHSMPITRLRISPDRQLITTVSEDGAIYFW 2008
            L L  VIGF G          D   ++Y     +++  ++T  Q F  GHT+ V  + ++ S   +AS Q+      + + LWD+ T  C+S F      + SL+FS +   L  +G    G  V+        +  S  Q    G    L   +T+ D+              + G  ++R+W L      +R     LG          A  +++         ++F C + SG IL ++ +         LL    P     EK+ FS+G    +S + +      VG+ DG +                ++     S +L+     G VSS++    G +  + T   H+    +   +  ++  +H + V  +    N  ++        VR++   + ++L   +    T               G+    +R+F  E+  ++   +  H+  +T++  T D R + S   +G +  +    C  SQ       AN +      R   N+ +V         V  +     + E A+    +R++       S+  D     W +                 +C+ P +   ++ S +  K+   +   G  +REL   RS +   + ++ D  + +    D+ + VW Y         V +GHS P+  +  +PD+  + +V +  AI+ W
Sbjct:  421 LRLKGVIGFGGHSTQWALWTKDGVAVVYPCHAVIIVLQIDTGQQRFFLGHTDKVSALALNGSDTLLASAQVQP---PSMVRLWDFQTGSCLSLFRSPLHTICSLSFSGSGALLCGVGKDRHGRTVV--------VAWSTEQAGLGGEVVVLAKVHTDFDIRAFQVAFFDETRMASCGRGSVRLWRL--RGGVLRSCAVDLGEYCSLELTDLAFAQALDGHCAPSAGTLFVC-SHSGHILEIDHQRMSVQHVRRLLPARSPGAPLAEKQNFSVGSGIAISSLSVSTATCAVGSEDGYL----------------RLWPLDFSSVLLEAEHDGPVSSVSFSPDGLRVLSTTTSGHLGFLDVPSREYTVLARSHMAPVLALSTEPNRGQMATVSLDHTVRIWDLATLQQLYDFSSSEDTPCAVAFHPTMPNFFCGFSSGAVRSFSLESSGVLVE-HTRHRGAITSLVITLDGRFLFSSCSQGSLVQY---SCADSQCCVLRVAANMV--CQDGRPNPNILAVSGDSCRLAFVGPSKCMVTIVESASLDELLRVDVSTLNLASNHLD-----WAV----------------AICFSPGNSGHLLVSTSSNKVVVLDAVSGHTLRELSSVRSRACCSLALSEDAHLLL-AATDRTITVWDYPTQANPSCQVYIGHSEPVHAVAFTPDQLQVISVGD--AIFLW 1058          

Query:  176 IYGLGCTVVIEDLNTKNQCFLQGHTNNVVCITVSNSGKYIASGQITHMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDGCVVIWSLTKMEPICGSPAQHKSAGITECLVYSNTNDDVFVTAGENTLRVWELDVENRKIRPTECSLGAIKRSIKCITISKDDSVFFCGTSSGDILGVNMKSCLLSCIGPEKETFSLGVLSIIRLINGDLIVGAGDGTICQVKVVEKKEGNKIMPKIVKTSNSCMLVGGVSSITLRGQGHQFYAGTEKSHIYRFSLGDFKSELINTAHYSAVNDIVYPNNCPKLFVTCSFQDVRVFHSDSQKELLRINIPNMTCYTCDIFKDGTAIITGWDDSKIRAFYPETGALMYTINDAHKKGVTAIAATSDCRKVVSGGGEGQVRVWRIEECKVSQANTIPHSHGNRKKSNVKSVVYVAHMETAMKEHANAVSCIRMNKDDTQCVSSSADGTCIIWCLIKYTRKQIMFANTLFRCVC 1693
            IYGLGCTVVIEDLNTKNQCFLQGHTNNVVCITVSNSGKYIASGQITHMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDGCVVIWSLTKMEPICGSPAQHKSAGITECLVYSNTNDDVFVTAGENTLRVWELDVENRKIRPTECSLGAIKRSIKCITISKDDSVFFCGTSSGDILGVNMKSCLLSCIGPEKETFSLGVLSIIRLINGDLIVGAGDGTICQVKVVEKKEGNKIMPKIVKTSNSCMLVGGVSSITLRGQGHQFYAGTEKSHIYRFSLGDFKSELINTAHYSAVNDIVYPNNCPKLFVTCSFQDVRVFHSDSQKELLRINIPNMTCYTCDIFKDGTAIITGWDDSKIRAFYPETGALMYTINDAHKKGVTAIAATSDCRKVVSGGGEGQVRVWRIEECKVSQANTIPHSHGNRKKSNVKSVVYVAHMETAMKEHANAVSCIRMNKDDTQCVSSSADGTCIIWCLIKYTRKQIMFANTLFRCVC
Sbjct:    1 IYGLGCTVVIEDLNTKNQCFLQGHTNNVVCITVSNSGKYIASGQITHMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDGCVVIWSLTKMEPICGSPAQHKSAGITECLVYSNTNDDVFVTAGENTLRVWELDVENRKIRPTECSLGAIKRSIKCITISKDDSVFFCGTSSGDILGVNMKSCLLSCIGPEKETFSLGVLSIIRLINGDLIVGAGDGTICQVKVVEKKEGNKIMPKIVKTSNSCMLVGGVSSITLRGQGHQFYAGTEKSHIYRFSLGDFKSELINTAHYSAVNDIVYPNNCPKLFVTCSFQDVRVFHSDSQKELLRINIPNMTCYTCDIFKDGTAIITGWDDSKIRAFYPETGALMYTINDAHKKGVTAIAATSDCRKVVSGGGEGQVRVWRIEECKVSQANTIPHSHGNRKKSNVKSVVYVAHMETAMKEHANAVSCIRMNKDDTQCVSSSADGTCIIWCLIKYTRKQIMFANTLFRCVC 506          

Query:   74 EEVNEINKLELINVIGFNGTILDGLHVHPDRQHIIYGLGCTVVIEDLNTKNQCFLQGHTNNVVCITVSNSGKYIASGQITHMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDGCVVIWSLTKMEPICGSPAQHKSAGITECLVYSNTNDDVFVTAGENTLRVWELDVENRKIRPTECSLGAIKRSIKCITISKDDSVFFCGTSSGDILGVNMKSCLLSCIGPEKETFSLGVLSIIRLINGDLIVGAGDGTICQVKVVEKKEGNKIMPKIVKTSNSCMLVGGVSSITLRGQGHQFYAGTEKSHIYRFSLGDFKSELINTAHYSAVNDIVYPNNCPKLFVTCSFQDVRVFHSDSQKELLRINIPNMTCYTCDIFKDGTAIITGWDDSKIRAFYPETGALMYTINDAHKKGVTAIAATSDCRKVVSGGGEGQVRVWRIEECKVS----QANTIPHSHGNRK-----KSNVKSVVYVAHMETAMKEHANAVSCIRMNKDDTQCVSSSADGTCIIWCLIKYTRKQIMFANTLFRCVCWRPDECQIITSGTDRKIGYWEVYDGSLIRELEGSRSGSVNGMDITADGDIFVTGGDDKIVKVWKYNEGYVTHVGLGHSMPITRLRISPDRQLITTVSEDGAIYFWKFPN 2020
            EE      L+L  VIG NG I     +HPDRQH ++ LGCTV+I+D+NT  Q FLQGHTNN+VC+TVS +G YIASGQ T+MGYKA I++W+Y T++  + F LHKVKVQ+LAFSPN  YLASLGGQDDG VVIWS+ K E ICGSPAQH+SAGIT  L Y+N +++ F+TAGENT+R+W+LD+ENRKIRP +C+LG IKR++ CI +  DD +FFCGTSSGDILG+NM S LL  + PEK  +SLGV +I  + N  L++G GDG + +  +   +EG++  PK+ +T     L G V++I+LRG+GHQFY  T+K ++Y F   DF  ELI ++HY+AVNDI +PN C +LF TCS+QDVRVF++ +Q+ELLRI IPNMTCY  DI  DGTAI++GWDDSKIRAFYPETG LMY+I++AHKKGVTAI +TS C +++SGGGEG +RVW I+E +          + H H   +      + +    +V  +  AM EH NAVSCI+++KDD  CVS+SAD TCIIWCL  + R+QI+F+NTLFRC+C+ P ECQ+ITSGTDRKIGYWEVYDGSLIR+L+GSRSGSVNGMDIT DG  FVT GDDKIVKVWKYNEG VTHVG+GHS P+TRLRISPD+  + TVSEDGAIY W  P 
Sbjct:    6 EEDLGFEHLKLSGVIGLNGKIPHSFTMHPDRQHAVFALGCTVIIQDMNTHEQHFLQGHTNNIVCLTVSKNGMYIASGQTTYMGYKASIIVWNYETREKYAEFVLHKVKVQALAFSPNSMYLASLGGQDDGSVVIWSIGKKEAICGSPAQHQSAGITLALAYANLDEEKFITAGENTVRIWQLDLENRKIRPRDCALGQIKRTVLCIAVYPDDDLFFCGTSSGDILGINMHSALLQIVSPEKNKYSLGVSTITAMSNSTLLIGTGDGVVQECAISYNREGHRCYPKLSRTKQEQKLSGKVTAISLRGEGHQFYVATDKCNLYLFKHADFSQELIYSSHYAAVNDIRFPNKCSELFATCSYQDVRVFNTGTQQELLRITIPNMTCYCLDILTDGTAILSGWDDSKIRAFYPETGRLMYSIHNAHKKGVTAICSTSKCNRIISGGGEGHLRVWDIKEIRPKIEKFGHRRLRHRHSAGRLEAGDDAGIPESSFVTVLVAAMHEHTNAVSCIQISKDDKSCVSASADSTCIIWCLETFRRRQIIFSNTLFRCICYHPTECQVITSGTDRKIGYWEVYDGSLIRQLDGSRSGSVNGMDITGDGKTFVTAGDDKIVKVWKYNEGEVTHVGIGHSSPVTRLRISPDQSKVITVSEDGAIYIWDMPQ 663          

Query:   74 EEVNEINKLELINVIGFNGTILDGLHVHPDRQHIIYGLGCTVVIEDLNTKNQCFLQGHTNNVVCITVSNSGKYIASGQITHMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDGCVVIWSLTKMEPICGSPAQHKSAGITECLVYSNTNDDVFVTAGENTLRVWELDVENRKIRPTECSLGAIKRSIKCITISKDDSVFFCGTSSGDILGVNMKSCLLSCIGPEKETFSLGVLSIIRLINGDLIVGAGDGTICQVKVVEKKEGNKIMPKIVKTSNSCMLVGGVSSITLRGQGHQFYAGTEKSHIYRFSLGDFKSELINTAHYSAVNDIVYPNNCPKLFVTCSFQDVRVFHSDSQKELLRINIPNMTCYTCDIFKDGTAIITGWDDSKIRAFYPETGALMYTINDAHKKGVTAIAATSDCRKVVSGGGEGQVRVWRIEECKVSQANTIPHSHGNRKKSN----------VKSVVYVAHMETAMKEHANAVSCIRMNKDDTQCVSSSADGTCIIWCLIKYTRKQIMFANTLFRCVCWRPDECQIITSGTDRKIGYWEVYDGSLIRELEGSRSGSVNGMDITADGDIFVTGGDDKIVKVWKYNEGYVTHVGLGHSMPITRLRISPDRQLITTVSEDGAIYFWKFPN 2020
            EE      L+L  VIG NG I     +HPDRQH ++ LGCTV+I+D+NT  Q FLQGHTNN+VC+TVS +G YIASGQ T+MGYKA I++W Y T++  + F LHKVKVQ+LAFSPN  YLASLGGQDDG VV+WS+ K E ICGSPAQH+SAGIT  L Y+N +++ FVTAGENT+R+W+LD+ENRKIRP +C+LG IKR++ CI +  DD +FFCGTSSGDILG+NM+S LL  + PEK  +SLGV +I  L N  L++G GDG + +  +   +EG++  PK+ +T     L G V++I+LRG+GHQFY  T+K ++Y F   D   ELI ++HY+AVNDI +PN C +LF TCS+QDVRVF++ +Q+ELLRI IPNMTCY  DI  DGTAI++GWDDSKIRAFYPETG LMY+I++AHKKGVTA+ +TS C +++SGGGEG +RVW I+E +  +     H    R+ S           +    +V  +  AM EH NAVSCI+++KDD  CVS+SAD TCIIWCL  + R+QI+F+NTLFRC+C+ P ECQ+ITSGTDRKIGYWEVYDGSLIR+L+GSRSGSVNGMDIT DG  FVT GDDKIVKVWKYNEG VTHVG+GHS P+TRLRISPD+  + TVSEDGAIY W  P 
Sbjct:    6 EEDLGFEHLKLSGVIGLNGKIPHSFTMHPDRQHAVFALGCTVIIQDMNTHEQHFLQGHTNNIVCLTVSKNGMYIASGQTTYMGYKASIIVWKYETREKYAEFVLHKVKVQALAFSPNSMYLASLGGQDDGSVVVWSIGKKEAICGSPAQHQSAGITLALAYANLDEEKFVTAGENTVRIWQLDLENRKIRPRDCALGHIKRTVLCIAVYPDDDLFFCGTSSGDILGINMQSALLQIVSPEKNKYSLGVSTITALSNSTLLIGTGDGVVQECAISYNREGHRCYPKLSRTKQEQKLSGKVTAISLRGEGHQFYVATDKCNLYLFKHADLSQELIYSSHYAAVNDIRFPNKCSELFATCSYQDVRVFNTGTQQELLRITIPNMTCYCLDILADGTAILSGWDDSKIRAFYPETGRLMYSIHNAHKKGVTALCSTSKCNRIISGGGEGHLRVWDIKEIR-PKIEKFGHRRPRRRHSTGRPEAGDDAGIPESTFVTVLVAAMHEHTNAVSCIQISKDDKSCVSASADSTCIIWCLETFRRRQIIFSNTLFRCICYHPTECQVITSGTDRKIGYWEVYDGSLIRQLDGSRSGSVNGMDITGDGKTFVTAGDDKIVKVWKYNEGEVTHVGIGHSSPVTRLRISPDQSKVITVSEDGAIYIWGMPQ 663          

Query:   74 EEVNEINKLELINVIGFNGT---ILDGLHVHPDRQHIIYGLGCTVVIEDLNTKNQCFLQGHTNNVVCITVSNSGKYIASGQITHMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDGCVVIWSLTKMEPICGSPAQHKSAGITECLVYSNTNDDVFVTAGENTLRVWELDVENRKIRPTECSLGAIKRSIKCITISKDDSVFFCGTSSGDILGVNMKSCLLSCIGPEKETFSLGVLSIIRLINGDLIVGAGDGTICQVKVVEKKEGNKIMPKIVKTSNSCMLVGGVSSITLRGQGHQFYAGTEKSHIYRFSLGDFKSELINTAHYSAVNDIVYPNNCPKLFVTCSFQDVRVFHSDSQKELLRINIPNMTCYTCDIFKDGTAIITGWDDSKIRAFYPETGALMYTINDAHKKGVTAIAATSDCRKVVSGGGEGQVRVWRIEECKVS------QANTIPHSHGNRKK---SNVKSVVYVAHMETAMKEHANAVSCIRMNKDDTQCVSSSADGTCIIWCLIKYTRKQIMFANTLFRCVCWRPDECQIITSGTDRKIGYWEVYDGSLIRELEGSRSGSVNGMDITADGDIFVTGGDDKIVKVWKYNEGYVTHVGLGHSMPITRLRISPDRQLITTVSEDGAIYFWKFPN 2020
            EE      L+L  VIG NG    I     +HPDRQH ++ LGCTV+I+D+NT  Q FLQGHTNN+VC+TVS +G YIASGQ T+MGYKA I++W Y T++  + F LHKVKVQ+LAFSPN  YLASLGGQDDG VVIWS+ K E ICGSPAQH+SAGIT  L Y+N +++ FVTAGENT+R+W+LD+ENRKIRP +C+LG IKR++ CI +  DD +FFCGTSSGDILG+NM S LL  + PEK  +SLGV +I  + N  L++G GDG + +  +   +EG++  PK+ +T     L G V++I+LRG+GHQFY  T+K ++YRF   DF  ELI ++HY+AVNDI +PN C +LF TCS+QDVRVF++ +Q+ELLRI IPNMTCY  DI  DGTAI++GWDDSKIRAFYPETG LMY+I++AHKKGVTAI +TS C +++SGGGEG +RVW I+E +        +     HS G  +    + +    +V  +  AM EH NAVSCI+++KDD  CVS+SAD TCIIWCL  + R+QI+F+NTLFRC+C+ P ECQ+ITSGTDRKIGYWEVYDGSLIR+L+GSRSGSVNGMDIT DG  FVT GDDKIVKVWKYNEG VTHVG+GHS P+TRLRISPD+  + TVSEDGAIY W  P 
Sbjct:    6 EEDLGFEHLKLSGVIGLNGKERKIPHSFTMHPDRQHAVFALGCTVIIQDMNTHEQEFLQGHTNNIVCLTVSKNGMYIASGQTTYMGYKASIIVWKYETREKYAEFVLHKVKVQALAFSPNSMYLASLGGQDDGSVVIWSIGKKEAICGSPAQHQSAGITLALAYANLDEEKFVTAGENTVRIWQLDLENRKIRPRDCALGQIKRTVLCIAVYPDDDLFFCGTSSGDILGINMHSALLQIVSPEKNKYSLGVSTITAMSNSTLLIGTGDGVVQECAISYTREGHRCYPKLSRTKQEQKLSGKVTAISLRGEGHQFYVATDKCNLYRFKHADFSQELIYSSHYAAVNDIRFPNKCSELFATCSYQDVRVFNTGTQQELLRITIPNMTCYCLDILTDGTAILSGWDDSKIRAFYPETGRLMYSIHNAHKKGVTAICSTSKCNRIISGGGEGHLRVWDIKEIRPKIERFGHRRPRRRHSAGRLEAGDDAGIPESTFVTVLVAAMHEHTNAVSCIQISKDDKSCVSASADSTCIIWCLETFRRRQIIFSNTLFRCICYHPTECQVITSGTDRKIGYWEVYDGSLIRQLDGSRSGSVNGMDITGDGKTFVTAGDDKIVKVWKYNEGEVTHVGIGHSSPVTRLRISPDQSKVITVSEDGAIYIWNMPQ 666          

Query:   65 MSGEEVNEIN--KLELINVIGFNGTILDGLHVHPDRQHIIYGLGCTVVIEDLNTKNQCFLQGHTNNVVCITVSNSGKYIASGQITHMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDGCVVIWSLTKMEPICGSPAQHKSAGITECLVYSNTNDDVFVTAGENTLRVWELDVENRKIRPTECSLGAIKRSIKCITISKDDSVFFCGTSSGDILGVNMKSCLLSCIGPEKETFSLGVLSIIRLINGDLIVGAGDGTICQVKVVEKKE-GNKIMPKIVKTSNSCMLVGGVSSITLRGQGHQFYAGTEKSHIYRFSLGDFKSELINTAHYSAVNDIVYPNNCPKLFVTCSFQDVRVFHSDSQKELLRINIPNMTCYTCDIFKDGTAIITGWDDSKIRAFYPETGALMYTINDAHKKGVTAIAATSDCRKVVSGGGEGQVRVWRIEECKVSQANTIPHSHGNRKKSNVKSVVYVAHMETAMKEHANAVSCIRMNKDDTQCVSSSADGTCIIWCLIKYTRKQIMFANTLFRCVCWRPDECQIITSGTDRKIGYWEVYDGSLIRELEGSRSGSVNGMDITADGDIFVTGGDDKIVKVWKYNEGYVTHVGLGHSMPITRLRISPDRQLITTVSEDGAIYFWKFP 2017
            M+ EE  +++  +LE+ ++IGFNG++L GL++HPD+QH IY +G T+V+EDL ++ Q FL GH +++ CIT+S SG++IASGQITHMG+KADI++WD+ T+   + F LHKVK+Q LAFSPN+K+L SLGGQDDG VV+WSL K E ICGSPAQ KS+G T CL YSN  D +FVTAG+N LRVWELDVENRKIRPT+   G  KR I CI+++ DD   +CGT++GD+LG+NM+S L   IGPEKE FSLGV +I  L  G+ ++GAGDGT+  ++  E+   G K   K VKT     L  GV+SI+LRG+GH+F+  TEKS IY+F+L DF   L+NT HYSA+NDI +P     LF TCS+QD+RV+H+ SQKELLRI +PNMTC+  D  +DG+ I++GWDDSKIR F+PETG LMY INDAHKKGVTAI ATSDC +++SGGGEG VRVWR+EE                 KS  K+  +V  +E A+KEHANAVSCIR++KD++QCVS+S+DG+CI+W L  + RKQIMFANTLFRCVC+ P+ECQ+ITSGTDRKI YWE+YDG+LIREL+GSRSGSVNGMDI+ DG  +VT GDDKIVKVW+Y EG VTHVG GHS PI R +I P+ +LI TVS+DG I+ WKFP
Sbjct:    1 MAHEEQEDVDFQQLEVQSIIGFNGSVLGGLNIHPDKQHQIYSIGSTLVVEDLQSRKQEFLHGHHSDIACITISRSGRFIASGQITHMGFKADIIVWDFNTRTEFARFVLHKVKIQGLAFSPNDKFLVSLGGQDDGSVVVWSLDKKEAICGSPAQSKSSGNTMCLTYSNNTDYLFVTAGDNNLRVWELDVENRKIRPTDVGTGQTKRIITCISLTMDDKTLYCGTTTGDVLGINMESRLFQHIGPEKEKFSLGVTAIALLETGEFLIGAGDGTVQIMRASEQAAPGGKKALKFVKTKKQQKLESGVTSISLRGRGHEFFVATEKSQIYKFNLADFSHTLVNTCHYSAINDIAFPFGTSDLFATCSYQDIRVWHTPSQKELLRITVPNMTCFAIDFLRDGSGIVSGWDDSKIRVFFPETGRLMYAINDAHKKGVTAITATSDCSRIISGGGEGHVRVWRVEE--------------RIAKSGQKT--FVTELEEALKEHANAVSCIRVSKDNSQCVSASSDGSCIVWDLRSFRRKQIMFANTLFRCVCFEPEECQVITSGTDRKICYWELYDGTLIRELDGSRSGSVNGMDISLDGQYYVTAGDDKIVKVWRYAEGDVTHVGQGHSSPIMRAKICPNNRLIVTVSDDGGIFVWKFP 638          

Query:   65 MSGEEVNEINKLELINVIGFNGTILDGLHVHPDRQHIIYGLGCTVVIEDLNTKNQCFLQGHTNNVVCITVSNSGKYIASGQITHMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDGCVVIWSLTKMEPICGSPAQHKSAGITECLVYSNTNDDVFVTAGENTLRVWELDVENRKIRPTECSLGAIKRSIKCITISKDDSVFFCGTSSGDILGVNMKSCLLSCIGPEKETFSLGVLSIIRLINGDLIVGAGDG--TIC---QVKVVEKKEGNKIMPKIVKTSNSCMLVGGVSSITLRGQGHQFYAGTEKSHIYRFSLGDFKSELINTAHYSAVNDIVYPNNCPKLFVTCSFQDVRVFHSDSQKELLRINIPNMTCYTCDIFKDGTAIITGWDDSKIRAFYPETGALMYTINDAHKKGVTAIAATSDCRKVVSGGGEGQVRVWRIEECKVSQANTIPHSHGNRKKSNVKSVVYVAHMETAMKEHANAVSCIRMNKDDTQCVSSSADGTCIIWCLIKYTRKQIMFANTLFRCVCWRPDECQIITSGTDRKIGYWEVYDGSLIRELEGSRSGSVNGMDITADGDIFVTGGDDKIVKVWKYNEGYVTHVGLGHSMPITRLRISPDRQLITTVSEDGAIYFWKFPNN 2023
            M+GEE  +++KLEL  VIGFNG +L GL  HPDR+H+IY LGCT++I++LN+  Q FL GHTNNV C+TVS SG+YIASGQ+T MG+KAD+++WDY  ++  +   LHKVKV++LAFSPNEK+L +LGGQDDG +V+W + K E ICGSPA    AG    + +S+ +D++F++AG NTLRVWELD  NRKI PT+C  G +KR IKCI I +DDS F+CGT+SGDIL VN+KS L++  GP K+ FS GV ++  L  GDL+VG+GDG  ++C     K++++ E                L G V+S+ LRG+G Q + GT  + IYRF   DFK ELI+T+H SAV+D  +P  C +LF TCS  D+RV+ +DS KE+LRI +PNMTC    I +DG +I + W+D KIR F PE+G L   I++AH  GVTAIA+  D  +++SGGGEGQVRVW I +                      S   VA    +MKEH  +V+ I++  +  +CV++S+DG CIIW L+++ R Q++ ANT F+ VC+ P+E QIITSGTDRKIGYWEV+DGS IREL GS +G++N MDI+ +G+ FVTGGD+K++KVW Y +G VTHVG+GHS  I+ +RI P+ ++I + S DGAI  W++P++
Sbjct:    1 MAGEE-QQVSKLELEAVIGFNGHVLSGLQSHPDREHVIYPLGCTLIIKNLNSGKQSFLHGHTNNVSCLTVSKSGRYIASGQVTFMGFKADVIVWDYSKREIYAQLILHKVKVEALAFSPNEKFLVTLGGQDDGSIVVWDVEKKEAICGSPASTDMAGHCLTVAFSSHSDNIFISAGNNTLRVWELDHTNRKIHPTQCQTGKLKRIIKCIEIPEDDSFFYCGTTSGDILKVNLKSRLMNSCGPVKQKFSKGVNTLKMLRTGDLLVGSGDGAFSLCSSTNFKIIKRVE----------------LEGAVTSVALRGEGQQMFVGTNAAQIYRFGYTDFKPELISTSHSSAVSDTAFPYGCSELFATCSQDDIRVWRTDSCKEVLRIKVPNMTCNALGITRDGHSIYSAWNDGKIRMFTPESGRLKLIIHNAHSLGVTAIASGKDSNRLISGGGEGQVRVWEIMQ---------------------DSYRLVA----SMKEHKASVNAIKIKSNGQECVTASSDGACIIWDLVRFVRNQMVLANTQFQTVCYHPEEYQIITSGTDRKIGYWEVFDGSAIRELYGSLTGAINSMDISQEGEHFVTGGDEKLIKVWHYTDGDVTHVGVGHSSSISSIRICPNSKVIISTSTDGAILRWRYPHS 616          

Query:   53 KKLRMSGEEVNEINKLELINVIGFNGTILDGLHVHPDRQHIIYGLGCTVVIEDLNTK---NQCFLQGHTNNVVCITVSNSGKYIASGQITHMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDGCVVIWSLTKMEPICGSPAQHKSAGITECLVYSNTNDDVFVTAGENTLRVWELDVENRKIRPTECS--------LGAIKRSIKCITI---SKDDSVFFCGTSSGDILGVNMKSCL 772
            KK R    + +  NK+ L  V+G   +   GL   P    + Y  GC VV+  LN K    Q  +      +  +  S+ GKY+ +G+  H+     + +WD      V     HK  V  +AFSPN KY+ S+G Q D  V +W+  K   +    A +K +     + +S  +   FVTAG   +R W L+  N   +PT           LG ++ +  C       K     FC TSSG +   N K  L
Sbjct:   26 KKNRPRANKESLSNKVTLERVLGITTSGSSGLTCDPYSGTVAYPAGCVVVL--LNPKKNRQQHIINTSRKTITTLAFSSDGKYLVTGESGHL---PAVRVWDAAEGSQVVELQEHKYGVACVAFSPNSKYIVSVGYQHDMSVNVWAWKKNTLV----ATNKVSSKVTAVSFSE-DSSYFVTAGNRHVRFWYLEPCNSNKQPTAPVPLLGRSGLLGELQNNFFCDVACGHGKKSESTFCITSSGLLCEFNAKRML 269          

Query:   92 NKLELINVIGFNGTILDGLHVHPDRQHIIYGLGCTVVI-EDLNTKNQCFLQGHTNNVVCITVSNSGKYIASGQITHMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDGCVVIWSLTKMEPICGSPAQHKSAGITECLVYSNTNDDVFVTAGENTLRVWELDVE-NRKIRPTECSLGA----------IKRSIKCITISKDDSVFFCGTSSGDILGVNMKSCLLSCIGPEK-ETFSLGVLSIIRLINGDLIVGAGDGTI 877
            NK+ L  V+G       GL   P    + Y  GC VV+      K    L      +  +  S  GKY+ +G+  HM     + +WD   +  V+    HK  V  +AFSPN KY+ S+G Q D  V +W+  K   +  +    K   ++    +S+ +   FVTAG   ++ W LD + + K+  T   LG               + C    K  S  FC TSSG +   N K  L   +   K ++ + G+ + + +    +  G  DGT+
Sbjct:   37 NKVTLEKVLGITSAGNRGLACDPRSGLVAYPAGCVVVLLNPKKNKQHHILNSSKKTITTVAFSPDGKYVVTGESGHM---PAVRVWDVAERTQVAELQEHKYGVACVAFSPNSKYIVSVGYQHDMIVNVWAWKKNVVVAANKVSSKVTAVS----FSD-DSSYFVTAGNRHVKFWYLDHDKSSKVNATVPLLGRSGLLGELRNNFFSDVACGKGRKAAST-FCITSSGLLCEFNDKRLLDKWVELRKNDSITTGLATSLSVTEDLIFCGCADGTV 302          

Query:   92 NKLELINVIGFNGTILDGLHVHPDRQHIIYGLGCTVVI-EDLNTKNQCFLQGHTNNVVCITVSNSGKYIASGQITHMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDGCVVIWSLTKMEPICGSPAQHKSAGITECLVYSNTNDDVFVTAGENTLRVWELDVE-NRKIRPTECSLGA----------IKRSIKCITISKDDSVFFCGTSSGDILGVNMKSCLLSCIGPEKETFSLGVLSIIRLINGDLIVGAGDGTI 877
            NK+ L  V+G       GL   P    + Y  GC VV+      K    L      +  +  S  GKY+ +G+  HM     + +WD   +  V+    HK  V  +AFSPN KY+ S+G Q D  V +W+  K   +  +    K   ++    +S+ +   FVTAG   ++ W LD + + K+  T   LG               + C    K  S  FC TSSG +   N K  L   +         G+ + + +    +  G  DGT+
Sbjct:   37 NKVTLEKVLGITSAGNRGLACDPRSGLVAYPAGCVVVLLNPKKNKQHHILNSSKKTITTVAFSPDGKYVVTGESGHM---PAVRVWDVAERTQVAELQEHKYGVACVAFSPNSKYIVSVGYQHDMIVNVWAWKKNVVVAANKVSSKVTAVS----FSD-DSSYFVTAGNRHVKFWYLDHDKSSKVNATVPLLGRSGLLGELRNNFFSDVACGKGRKAAST-FCITSSGLLCEFNDKRLLDKWV-----ELRTGLATSLSVTEDLIFCGCADGTV 296          

Query:   89 INKLELINVIGFNG-TILDGLHVHPDRQHIIYGLGCTVVIEDLNTKNQCFLQGHTNNVVCITVSNSGKY---IASGQITHMGYKADIMLWDYVTKQCVSTFSL-HKVKVQSLAFSPNEKYLASLGGQDDGCVVIWSLTKMEPICGSPAQHKSAGITECLVYSNTNDDVFVTAGENTLRVWEL 619
            + +L L +V G+ G    + LH   D   II+      VI++L+   Q F   HT++++C+TV+   KY   IA+GQI   G    I +WD ++KQ +S     H   V  + FS   K L S+G   +  + +W   +   +           + E   +   +D  FV+ G   ++ W L
Sbjct: 1350 VEELALDHVFGYRGFDCRNNLHYLNDGADIIFHTAAAAVIQNLSAGTQSFYLEHTDDILCLTVNQHPKYQNIIATGQI---GLAPSIHVWDAMSKQTLSVLRCSHAKGVGYVNFSATGKLLLSVGVDPEHTITVWRWQEGSKVSSKAGHSDRIFVVE---FRPDSDTQFVSVGIKHIKFWTL 1525          

Query:  173 IIYGLGCTVVIEDLNTKNQCFLQGHTNNVVCITVSNSGKYIASGQITHMGYKADIMLWDYVTKQCVSTF-SLHKVKVQSLAFSPNEKYLASLGGQDDGCVVIWSLTKMEPICGSPAQHKSAGITECLVYSNTND---DVFVTAGENTLRVWELDVENRKI-RPTECSLGAIKRSIKCITISKDDSVFFCGTSSGDI 745
            ++Y +    V+ +     Q F  GH ++++ +T      Y+A+GQ+   G    I +WD  T +C+S     H+  V +L F+ + K L S+G  +   +V+W   K E +       K+ G  + +     N    D  VT G   ++ W+         R    +LG  + ++      + + + F G ++GD+
Sbjct:  695 VVYHVAAVGVVYNRQQHTQRFYLGHDDDILSLTAHPLKDYVATGQV---GRDPAIHVWDIQTLKCLSLLRGQHQRGVCALEFTADGKSLVSVGIDEGHSIVMWDWKKGEKLA------KARGHKDKIFVVKGNPFRMDKLVTVGIKHIKFWQHTGGGLTFKRGIFGNLGK-QETMMSACYGRSEDLVFSGATTGDV 880          

Query:   95 KLELINVIGFNGTILDGLHVHPDRQHIIYGLGCTVVIEDLNTKNQCFLQGHTNNVVCITVSNSGKYIASGQITHMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDGCVVIWSLTKMEPICGSPAQHKSAGITECLVYSNTNDDVFVTAGENTLRVWELDVENRKIRPTECSLGAIKRSIKCITISKDDSVFFCGTSSGDILGVNMKSCLLSCIGPEKETFSLGVLSIIRLINGDLIVGAGDGTICQVKVVEKKEGNKIMPKIVKTSNSCMLVGGVSSITLRGQGHQFYAGTEKSHIYRFSLGDFKSELINTAHYSAVNDIVYP---NNCPKLFVTCSFQDVRVFHSDSQKELLRINIPNMTCYTCDIFKDGTAIITGWDDSKIRAFYPETGALMYTINDAHKKGVTAIAATSDCRKVVSGGGEGQVRVWRIEECKVSQANTIPHSHGNRKKSNVKSVVYVAHMETAMKEHANAVSCIRMNKDDTQCVSSSADGTCIIWCLIKYTRKQIMFANTLFRCVCWRPDECQIITSGTDRKIGYWEVYDGSLIRELEGSRSGSVNGMDITADGDIFVT--GGDDKIVKVWKYNEGYVTHVGLGHSMPITRLRISPDRQLITTVSEDGAIYFWKFPNN 2023
            +LEL +VIGFNG +  GL  HPD +H++Y LGCTVVI  L    Q FL GHTNNV C+ VSNSG Y+ASGQ+T+MG+KAD++LW++  ++  +  +LHKVKV++LAFSPN+ YLASLGGQDDG VVIW++TK E +CG+     +AG T  + ++NT+D  F+TAG +T+RVW+LD+ NRKIRPT+C  G +KR IKC+ ++ DDS F+CGT+SGDIL VN+K+ LL+  GP K   +LGV ++  L +G+L+VG GDG +        KE N       KT     L G V+SI+LRGQGHQF+AGT  + IY+F+L +F  E+I T H   VND+ +P   +   +LF TCS QD+RV+H+ S KELLRI +PNMTC++    ++G  I++GW+D KIRAF PE+G LMY I++AH  GVT ++ T DC++++SGG  GQVRVW +               G + +  V+          AMKEH +++SCIR+  +D +CVS+S DGTCIIW L ++ RKQI+ ANTLF+C C+ P+E QIITSGTDRKIG+WEV+DGSLIRELE S+SGS+NGMD++ DG+ FVT  GGDDK++KVW YN+G VT VG GHS  +TRL + P+R  I +VS DGAI  W++P++
Sbjct:   13 RLELESVIGFNGQVPSGLVSHPDCEHLLYPLGCTVVIRSLKGARQSFLHGHTNNVSCLAVSNSGHYVASGQVTYMGFKADVILWNFEKRELHARLTLHKVKVEALAFSPNDLYLASLGGQDDGSVVIWNVTKKEAVCGNAVSLPTAGTTNTVRFTNTSDLSFITAGNDTIRVWQLDIPNRKIRPTDCQTGQLKRIIKCVAVAPDDSFFYCGTTSGDILKVNLKTKLLNSYGPAKNKLTLGVTALSLLKSGELLVGTGDGVVALC-----KEAN------FKTMQKVALEGAVTSISLRGQGHQFFAGTAVAQIYQFNLPEFTHEMIATCHSEPVNDVAFPFITSGTSELFATCSSQDIRVWHTQSGKELLRITVPNMTCHSIQFARNGKNIVSGWNDGKIRAFTPESGRLMYIIDNAHGMGVTTVSLTGDCKRIISGGVSGQVRVWEL---------------GTQSQRLVE----------AMKEHKSSISCIRLKHNDKECVSASTDGTCIIWDLERFVRKQIVMANTLFKCACYHPEEFQIITSGTDRKIGFWEVFDGSLIRELEASQSGSINGMDVSPDGEYFVTVKGGDDKLIKVWSYNDGDVTFVGKGHSGNVTRLCVCPNRWHILSVSTDGAILRWRYPHS 624          

Query:   53 KKLRMSGEEVNEINKLELINVIGFNGTILDGLHVHPDRQHIIYGLGCTVVIEDLNTKNQCFLQGHTNNVVCITVSNSGKYIASGQITHMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDGCVVIWSLTKMEPI-----CGSPAQHKSAGITECLVYSNTNDDVFVTAG---------ENTLRVWELDVENRKIRPTECSLGAIKRSIKCITISKDDSVFFCGTSSGDILGVN--MKSCLLSCIGPEKETFSLGVLSIIRLINGDLIVGAGDGTICQVKVVEKKEGNKIMPKIVKTSNSCMLVGGVSSITLRGQGHQF-------YAGTEKSHIYRFSLGDFKSELINTAHYSAVNDIVYPNNCPKLFVTCSFQDVRVFHSDSQKELLRINIPNMTCYTCDIFKDGTA--------IITGWDDSKIRAFYPETGALMYTINDAHKKGVTAIAATSDCRK-VVSGGGEGQVRVWRIEECKVSQANTIPHSHGNRKKSNVKSVVYVAHMET-AMKEHANAVSCIRMNKDDTQCVSSSADGTCIIWCLIKYTRKQIMFANTL-FRCVCWRPDECQIITS---------------------GTDRKIGYWEVYDGSLIRELEGSRSGSVNGMDITADGDIFVTGGDDKIVKVWKYNEGYVTHVGLGHSMPITRLRISPD-RQLITTVSEDGAIYFWKFPNN 2023
            K+ +       E+  L L  V+G+NG     L   PD   + Y  GC VV+E+L + +Q  L GH   +  + +S+  + + S     M       +WD  +  C S  S H+  VQ+LAFS ++++L SLG   DG + +W++ +   +     C  PA          L +       FV A          E   R + L ++   + P    LG  + +  C        V F GTSSG +   +   KSC L+    E ++ +LGVL       G  +V AG G   +   V   +  ++  +  + ++ C+++     +        F         GT    ++     +  S  + + H   V  + +  +      + +   +RV+ + S +  ++  +   TC  C  +    A        +  G+ D  +R F   +  ++  +  +H   VTA+A ++D  + +VSG  +G V V  +     ++  T      + + S + ++  V   E   +  H   +            +++S D    IW    + R +    + L F  +    D+ Q   S                     G  R+I ++ +    ++R+L          +D++ +GD+   G  +++V +     G    V  GH   +   R SP  R+L T  +  GAI+ W+  N+
Sbjct: 1183 KQQQQQPTTAGELPGLRLKAVVGYNGNGRGNLVWRPDNGLLAYSSGCVVVVEELRSGDQRHLLGHQREISTLAISHDAQTLVSASCGQM------CMWDVASGVCRSGPSHHRGDVQALAFSRDDRFLLSLGDGRDGSLALWAVQQDVSLLASVRCPVPAH--------ALAFRPGRAGEFVCAASGHIAFGLVEQRGREFGLSLDMVAVPP---ELGGAEVTCVCYGAG---GVVFAGTSSGLVSAWDSERKSCFLTW---EADSLALGVLE----CRGHSLVTAGAGRRLRRWSVASVDAARVQERGTRGAD-CVVLEAELRLDASAVSAAFDDDLDMGVVGTAVGTVWFIGWAECSSMRLVSGHAEQVTGLAFSPDEALFASSAADGSLRVWDARSLELSVQFQVLQQTC-ECVAWSRVPARRSRFSRLVAAGYGDGAVRLFSLRSVEMVLKMR-SHGSAVTALAFSTDAGEFLVSGARDGLVVVSSLHTGATARVVT------DHRPSPISAIDCVHSQERLVIGSHGGEM-----------WLAASRDSRVSIWS-CDWLRDRCDLVDWLTFPALSAGLDDTQSGRSTPPSLAVFCPGDVDTVVYAGYGLQREIVFYSLRLKQVVRKLP--LDNWALSLDLSCNGDLIAVGTYERLVGLMDPASGRFRSV-WGHEDAVRACRFSPSGRRLFT--AAHGAIFVWEVCNS 1842          

Query:   98 LELINVIGFNGTILDGLHVHPDRQH--IIYGLGCTVVIEDLNTKNQCFLQGHTNNVVCITVSNSGKYIASGQITHMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLG--GQDDGCVVIWSLTKMEPICGSPAQHKSAGITECLVYSNTNDDV------------FVTAGENTLRVWELDVENRKIRPTECSLG----------AIKRSIKCITISKDDSVFFCGTSSGDILGVNMKSC-------LLSCIGPEKETFSL----GV-LSIIRLINGDLIVGAGDGTICQVKVVEKKEGNKIMPKIVKTSNSCMLV-----GGVSSITLRGQGHQFYAGTEKSHIYRFSLGDFKSELINTAHYSAVNDIV--YPNNCPKLFVTCSFQ-DVRVFHSDSQKELLRIN----IPNMTCYTCDIFKDGTAIITGWDDSKIRAFYPETGALMYTINDAHKKGVTAIAATSDCRKVVSGGGEGQVRVWRIEECKVSQANTIPHSHGNRKKSNVKSVVYVA---HMETAMKEHANAVSCIRMNKDDTQCVSSSADGTCIIWCLIKYTRK-QIMFANTLFRCVCWRPDECQIITSGTDRKIGYWEVYDGSLIRELEGSRSGSVNGMDITADGDIFVTGGDDKIVKVWKYNEGYVT--HVGLGHSMPITRLRISPDRQLITTVSEDGAIYFWKF 2014
            L L  VIGF G      H    RQ   I+Y     ++  ++ T NQ FL GH++ V  +T++ +   +AS Q    G  + + +WD+ + +C+S F+ H   + SL+FS +   L  +G    +   VV+W  +++          ++ G+   +  ++T+ D+             V+ G  ++R+W   V    +R     L           A +  +       D ++F C + SG IL ++ K+        LL   G     +S+    G+ ++ + +  G    G+ DG +                ++     S ML+       VS++ +   G +  A T           +  S    T   S    ++    +   +  VT      VRV+ SD+ ++LL  +    +P + C  C   +    +  G+ D  +RAF   + AL+   +  H+  +TA+A +     + S    G + ++   +  +     +          +  SV+ ++        +    +AV+ +     +     S + GT          R   + FA          PD  +++     R+I   +   G  +REL  +        D++ DG  F T G D++VKVW     + T     +GHS  +  +  +PD+  + +V +  AI  W F
Sbjct:  374 LALRRVIGFGGGTTR--HALWTRQGDVIVYPCHAIIIAVEITTGNQRFLTGHSDKVTALTMNGASTLLASAQ---AGAVSLLRVWDFSSGECLSVFTPHLHALSSLSFSHSGAVLCGVGKDSHEKNTVVVWDTSRL----------RTGGLVSVVARTHTDVDLHTIKIASFDDTRMVSCGRGSVRLWR--VRGSALRSCPVDLAEFHAAHFTDVAFEEGLPADREPHDRTLFAC-SKSGHILEIDYKNVTIRNVRRLLPSPGVRASEYSIPSGPGIGINSMSVSEGLCATGSDDGFL----------------RLWLLDFSTMLLEAEHEAPVSAVAISADGRRVLAATAGPAGASLGFLEVASRHYATLARSHAGPVLGCSADGARRHLVTVGRDASVRVWDSDNGQQLLDFSTLAVVPCVVC--CHPVRQ--LLACGFSDGSLRAFSVASTALLAE-HKQHRGQITALAFSRSGEFMYSACSLGSLAMYDASDDDLPALRVLGEPACQYDGDDAPSVLALSTDGRRLAFVGPSQDAVTVMDARSLEEVLRVSVSAGTATGHEDPGPERALAVRFAP---------PDSSRLLVLMRSRRIVVLDAATGRNLRELSAAHHTRCVSTDVSEDGRFFATAG-DRVVKVWDARAQHRTDAQTFIGHSESVRHVMFTPDQLGLVSVGD--AILIWDF 1017          

Query:   98 LELINVIGFNGTILDGLHVHPDRQH--IIYGLGCTVVIEDLNTKNQCFLQGHTNNVVCITVSNSGKYIASGQITHMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLG--GQDDGCVVIWSLTKMEPICGSPAQHKSAGITECLVYSNTNDDV------------FVTAGENTLRVWELDVENRKIRPTECSLG----------AIKRSIKCITISKDDSVFFCGTSSGDILGVNMKSCLLSCIGPEKETFSLGVLS-IIRLINGDLIVGAGDGT-ICQVKVVE---KKEGNKIMPKIVKTSNSCMLV-----GGVSSITLRGQGHQFYAGTEKSHIYRFSLGDFKSELINTAHYSAVNDIV--YPNNCPKLFVTCSFQ-DVRVFHSDSQKELLRIN----IPNMTCYTCDIFKDGTAIITGWDDSKIRAFYPETGALMYTINDAHKKGVTAIAATSDCRKVVSGGGEGQVRVWRIEECKVSQANTIPHSHGNRKKSNVKSVVYVA---HMETAMKEHANAVSCIRMNKDDTQCVSSSADGTCIIWCLIKYTRK-QIMFANTLFRCVCWRPDECQIITSGTDRKIGYWEVYDGSLIRELEGSRSGSVNGMDITADGDIFVTGGDDKIVKVWKYNEGYVT--HVGLGHSMPITRLRISPDRQLITTVSEDGAIYFWKF 2014
            L L  VIGF G      H    RQ   I+Y     ++  ++ T NQ FL GH++ V  +T++ +   +AS Q    G  + + +WD+ + +C+S F+ H   + SL+FS +   L  +G    +   VV+W  +++          ++ G+   +  ++T+ D+             V+ G  ++R+W   V    +R     L           A +  +       D ++F C + SG IL ++ K+  +  +   +   S GV + I+ L   +  + +G G  I  + V E       +    ++     S ML+       VS++ +   G +  A T           +  S    T   S    ++    +   +  VT      VRV+ SD+ ++LL  +    +P + C  C   +    +  G+ D  +RAF   + AL+   +  H+  +TA+A +     + S    G + ++   +  +     +          +  SV+ ++        +    +AV+ +     +     S + GT          R   + FA          PD  +++     R+I   +   G  +REL  +        D++ DG  F T G D++VKVW     + T     +GHS  +  +  +PD+  + +V +  AI  W F
Sbjct:  363 LALRRVIGFGGGTTR--HALWTRQGDVIVYPCHAIIIAVEITTGNQRFLTGHSDKVTALTMNGASTLLASAQ---AGAVSLLRVWDFSSGECLSVFTPHLHALSSLSFSHSGAVLCGVGKDSHEKNTVVVWDTSRL----------RTGGLVSVVARTHTDVDLHTIKIASFDDTRMVSCGRGSVRLWR--VRGSALRSCPVDLAEFHAAHFTDVAFEEGLPADREPHDRTLFAC-SKSGHILEIDYKNVTIRNV--RRLLPSPGVRARIMTLSPCEYSIPSGPGIGINSMSVSEGLCATGSDDGFLRLWLLDFSTMLLEAEHEAPVSAVAISADGRRVLAATAGPAGASLGFLEVASRHYATLARSHAGPVLGCSADGARRHLVTVGRDASVRVWDSDNGQQLLDFSTLAVVPCVVC--CHPVRQ--LLACGFSDGSLRAFSVASTALLAE-HKQHRGQITALAFSRSGEFMYSACSLGSLAMYDASDDDLPALRVLGEPACQYDGDDAPSVLALSTDGRRLAFVGPSQDAVTVMDARSLEEVLRVSVSAGTATGHEDPGPERALAVRFAP---------PDSSRLLVLMRSRRIVVLDAATGRNLRELSAAHHTRCVSTDVSEDGRFFATAG-DRVVKVWDARAQHRTDAQTFIGHSESVRHVMFTPDQLGLVSVGD--AILIWDF 1013          

Query:   98 LELINVIGFNGTILDGLHVHPDRQHIIYGLGCTVVIEDLNTKNQCFLQGHTNNVVCITVSNSGK-----YIASGQITHMGYKA--DIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDGCVVIWSLTKMEPI-----CGSPAQHKSAGITECLVYSNTNDDVFVTAG---------ENTLRVWELDVENRKIRPTECSLGAIKRSIKCITISKDDSVFFCGTSSGDILGVN--MKSCLLSCIGPEKETFSLGVLSIIRLINGDLIVGAGDGTICQVKVVEKKEGNKIMPKIVKTSNSCMLVGGVSSITLRGQGHQF-------YAGTEKSHIYRFSLGDFKSELINTAHYSAVNDIVYPNNCPKLFVTCSFQDVRVFHSDSQKELLRINIPNMTCYTCDIFKDGTA--------IITGWDDSKIRAFYPETGALMYTINDAHKKGVTAIAATSDCRK-VVSGGGEGQVRVWRIEECKVSQANTIPHSHGNRKKSNVKSVVYVAHMET-AMKEHANAVSCIRMNKDDTQCVSSSADGTCIIWCLIKYTRKQIMFANTL-FRCVCWRPDECQIITS---------------------GTDRKIGYWEVYDGSLIRELEGSRSGSVNGMDITADGDIFVTGGDDKIVKVWKYNEGYVTHVGLGHSMPITRLRISPD-RQLITTVSEDGAIYFWKFPNN 2023
            L L  V+G+NG     L   PD   + Y  GC VV+E+L + +Q  L GH   +  + +S+  +       AS Q   +   +   + +WD  +  C S  S H+  VQ+LAFS ++++L SLG   DG + +W++ +   +     C  PA          L +       FV A          E   R + L ++   + P    LG  + +  C        V F GTSSG +   +   KSC L+    E ++ +LGVL       G  +V AG G   +   V   +  ++      TS  C+++     +        F         GT    ++     +  S  + + H   V  + +  +      + +   +RV+ + S +  ++  +   TC  C  +    A        +  G+ D  +R F   +  ++  +  +H   VTA+A ++D  + +VSG  +G V V  +     ++  T      + + S + ++  V   E   +  H   +            +++S D    IW    + R +    + L F  +    D+ Q   S                     G  R+I ++ +    ++R+L          +D++ +GD+   G  +++V +     G    V  GH   +   R SP  R+L T  +  GAI+ W+  N+
Sbjct: 1126 LRLKAVVGYNGNGRGNLVWRPDNGLLAYSSGCVVVVEELRSGDQRHLLGHQREISTLAISHDAQVSKSPLPASVQTPTLVSASCGQMCMWDVASGVCRSGPSHHRGDVQALAFSRDDRFLLSLGDGRDGSLALWAVQQDVSLLASVRCPVPAH--------ALAFRPGRAGEFVCAASGHIAFGLVEQRGREFGLSLDMVAVPP---ELGGAEVTCVCYGAG---GVVFAGTSSGLVSAWDSERKSCFLTW---EADSLALGVLE----CRGHSLVTAGAGRRLRRWSVASVDAARVQ----CTSADCVVLEAELRLDASAVSAAFDDDLDMGVVGTAVGTVWFIGWAECSSMRLVSGHAEQVTGLAFSPDEALFASSAADGSLRVWDARSLELSVQFQVLQQTC-ECVAWSRVPARRSRFSRLVAAGYGDGAVRLFSLRSVEMVLKMR-SHGSAVTALAFSTDAGEFLVSGARDGLVVVSSLHTGATARVVT------DHRPSPISAIDCVHSQERLVIGSHGGEM-----------WLAASRDSRVSIWS-CDWLRDRCDLVDWLTFPALSAGLDDTQSGRSTPPSLAVFCPGDVDTVVYAGYGLQREIVFYSLRLKQVVRKLP--LDNWALSLDLSCNGDLIAVGTYERLVGLMDPASGRFRSV-WGHEDAVRACRFSPSGRRLFT--AAHGAIFVWEVCNS 1780          

Query:   98 LELINVIGFNGTILDGLHVHPDRQHIIYGLGCTVVIEDLNTKNQCFLQGHTNNVVCITVSNSGKYIASGQITHMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDGCVVIW------------SLTKMEPICGSPAQHKSAGITECLVYSNTNDDVFVTAGENTLRVWELDVENRKIRPTECSLGAIKRSIKCITISKDDSVFFCGTSSGDILG--VNMKSCLLSCIGPEKETFSLGVLSIIRLINGDLIVGAGDGTICQVKVVEKKEG----NKIMPKIVKTSNSCMLVGGVSSITLRGQGHQFYAGTEKSHIYRFSLGDFKSELINTAHYSAVNDIVYPNNCPKLFVTCSFQDVRVFHSDSQKELLRINIPNMTCYTCDIFKDGTA----IITGWDDSKIRAFYPETGALMYTINDAHKKGVTAIAATSDCRKVVSGGGEGQV 1414
            L L  V+GFNG     +  +PD     Y  G  +V+EDL+T  Q  LQ HT  +  +  S+  + +AS         + I +WD     C    S H+ +VQ++AFS +   L S+G   +  VV+W            S+  +  +C  P+   +AG   C+    +    F  A      + E  V      P     GA + S     +   DS+ F  ++ G +     + + CLLS    + +T  +GVL      +G+ ++        ++  VE             + V      +L G V S            GT    ++  +  +     + + H   VNDI +  +  +L        +RV+     + +++  + + +C TC  ++   A    +  G+ D  +R F   +   ++ +   H   +  +A +SD   +++GG +G+V
Sbjct: 1096 LRLSMVVGFNGNARGNVIWNPDSGLFAYTCGSLLVLEDLHTGAQRHLQAHTEEISTLASSHDAEVLASASGGRGDTGSQICVWDARRGSCERVLSRHRHEVQAMAFSADNSVLLSVGDYREMMVVLWDTRTYAVIAATRSVFPINDVCPDPS---AAGAFLCV---GSGAIAFCRAQN----LGETAVLQLSAAPLPNGAGASELS---AAVMGPDSLLFTASACGRVAAWDADRRRCLLSW---DADTADIGVL----CCHGNRLLSGSSSKRIRLWCVESVSATICVTSTASEFVSMEGEMVLDGAVVSAAFDDVMEMGIVGTAAGTLWYINWTERACVRLVSGHRGKVNDIAFSPDGSQLVSGSEDGLLRVWSVPEMELVVQFQVLHRSC-TCVAWRPSGAAPSQVAAGFGDGTLRLFGVASARTLHKLQ-PHGAAIRCVAFSSDGEVMLTGGADGRV 1534          

Query:   98 LELINVIGFNGTILDGLHVHPDRQ--HIIYGLGCTVVIEDLNTKNQCFLQGHTNNVVCITVSNSGKYIASGQITHMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDG--CVVIW---SLTKMEPICGSPAQHKSAGITECLVYSNTNDDVFVTAGENTLRVWELDVENRKIRPTECSLGAIKRSIKCITIS----KDDSVFFCGTSSGDILGVNMKSCLL------------------------SCIGPEKETFSLGVLSIIRLINGDLIVGAGDGTICQVKVVEKKEGNKIMPKIVKTSNSCMLVGGVSSITLRGQGHQFYAGTEKSHIYRFSLGDFKSELINTAHYSAVNDIVYPNNCPKLFVTCSFQDVRVFHSDSQKELLRINIPNMTCYTCDIFKDGTAIITGWDDSKIRAFYPETGALMYTINDAHKKGVTAIAATSDCRKVVSGGGEGQVRVWRIEECKVSQANTIPHSHGNRKKSNVKSVVYV----AHMETAMKEH-----ANAVSCIRMNKDDTQCVSSSADGTCIIWCLIKYTRKQIMFANTLFRCVCWRPDECQIITSGTDRKIGYWEVYDGSLIRELEGSRSGSVNGMDITADGDIFVTGGDDKIVKVWKYNEGY---VTHVGLGHSMPITRLRISPDRQLITTVSEDGAIYFWKF 2014
            L+L  V+GF G     +     R    ++Y     +V  D+ T +Q FL GH++ V  +    + + +ASGQ    G +A + +W++    C++ F  H   + SL+FS +   L+ +G    G   VV+W    +T    +      H    + + +V S  ++   V+ G + +RVW L  +N  +R     LG +  S +   ++    +D S  F  T SG IL ++ K  ++                        +C+G E    +L  L++ R      + G+ DGT+               P   +      L G VS + +   G    AGT   H+ R  +G      +  +    + D        ++    +   + ++   + ++L   +    +  T            G+    +R F    GA +   +  H+  +T +  + +   + S    G + ++    CK      +      R  S   S + V    AH+            A+A S   + + D   V +S+        L +  R            VC+ P   Q++ +    K+ +++   G L++E+   +    + + ++ DG I V    D  ++ W    G     +   +GHS  + RLR +   +    VS  G I+ W  
Sbjct:  359 LKLRRVVGFGGETNGYVQALWTRNGATLVYPCHAVIVALDVETSSQHFLTGHSDKVSALAFDGNTEILASGQ---SGPQAIVRIWNFQKGSCLAMFKTHAHSLFSLSFSWSGDVLSGVGRDSHGKTMVVVWDTSGVTHRRDVLILAKAHTGVDV-QTMVISPFDESRLVSCGRDNVRVWRL--QNGSLRSCAVDLGDLH-STEVTDVAFQQHRDSSRRFACTRSGHILDIDYKHNVVREVTRLRQPPSRSPRERLPDQGASACVGFE---LALTRLAVSRWF---CVTGSEDGTV-----------RVWSPDFSRVLLQTDLGGAVSLLGVSADGRHVLAGTRTGHLARLDVGGRSYATVTRSPVGPLLDFSLDLERQRVAAVSTNGSLTIWDLGTGQQLYEFSGAEDSACTVSCHPQLERFACGFSSGSVRVF-DVVGARLLAQHRQHRGEITGLEFSPNGEHMYSCDARGSLALYS-AICKEHTLVRLLSGVVARGTSYAPSALAVSGDGAHLAFVGPSEFAVTVADARSLCELLRVDVSIVDASSP------TLDQAER------------VCFGP-AGQLLVATASGKVLWFDARTGRLLKEVRDVQGAGCSALQVSEDGAI-VAMASDATLRAWDPGSGLEVQPSQAFVGHSQEVRRLRFT--GRCPGLVSGGGTIFMWDL 996          

Query:   98 LELINVIGFNGTILDGLHVHPDRQHIIYGLGCTVVIEDLNTKNQCFLQGHTNNVVCITVSNSGKYIASGQITHMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDGCVVIW------------SLTKMEPICGSPAQHKSAGITECLVYSNTNDDVFVTAGENTLRVWELDVENRKIRPTECSLGAIKRSIKCITISKDDSVFFCGTSSGDILG--VNMKSCLLSCIGPEKETFSLGVLSIIRLINGD-LIVGAGDGTI---CQVKVVEKKEG------NKIMPKIVKTSNSCMLVGGVSSITLRGQGHQFYAGTEKSHIYRFSLGDFKSELINTAHYSAVNDIVYPNNCPKLFVTCSFQDVRVFHSDSQKELLRINIPNMTCYTCDIFKDGTA----IITGWDDSKIRAFYPETGALMYTINDAHKKGVTAIAATSDCRKVVSGGGEGQV 1414
            L L  V+GFNG     +  +PD     Y  G  +V+EDL+T  Q  LQ HT  +  +  S+  + +AS         + I +WD     C    S H+ +VQ++AFS +   L S+G   +  VV+W            S+  +  +C  P+   +AG   C+    +    F  A      + E  V      P     GA + S     +   DS+ F  ++ G +     + + CLLS    + +T  +GVL      +G+ L+ G+    I   C   V    EG           + V      +L G V S            GT    ++  +  +     + + H   VNDI +  +  +L        +RV+     + +++  + + +C TC  ++   A    +  G+ D  +R F   +   ++ +   H   +  +A +SD   +++GG +G+V
Sbjct: 1190 LRLSMVVGFNGNARGNVIWNPDSGLFAYTCGSLLVLEDLHTGAQRHLQAHTEEISTLASSHDAEVLASASGGRGDTGSQICVWDARRGSCERVLSRHRHEVQAMAFSADNSVLLSVGDYREMMVVLWDTRTYAVIAATRSVFPINDVCPDPS---AAGAFLCV---GSGAIAFCRAQN----LGETAVLQLSAAPLPNGAGASELS---AAVMGPDSLLFTASACGRVAAWDADRRRCLLSW---DADTADIGVL----CCHGNRLLSGSSSKRIRLWCVESVSATMEGGVRESVTSTASEFVSMEGEMVLDGAVVSAAFDDVMEMGIVGTAAGTLWYINWTERACVRLVSGHRGKVNDIAFSPDGSQLVSGSEDGLLRVWSVPEMELVVQFQVLHRSC-TCVAWRPSGAAPSQVAAGFGDGTLRLFGVASARTLHKLQ-PHGAAIRCVAFSSDGEVMLTGGADGRV 1634          

Query:   98 LELINVIGFNGTILDGLHVHPDRQHIIYGLGCTVVIEDLNTKNQCFLQGHTNNVVCITVSNSGKYIASGQITHMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDG--CVVIW---SLTKMEPICGSPAQHKSAGITECLVYSNTNDDVFVTAGENTLRVWELDVENRKIRPTECSLGAIKR------SIKCITISKDDSVFFCGTSSGDILGVNMKSCLL------------------------SCIGPEKETFSLGVLSIIRLINGDLIVGAGDGTICQVKVVEKKEGNKIMPKIVKTSNSCMLVGGVSSITLRGQGHQFYAGTEKSHIYRFSLGDFKSELINTAHYSAVNDIVYPNNCPKLFVTCSFQDVRVFHSDSQKELLRINIPNMTCYTCDIFKDGTAIITGWDDSKIRAFYPETGALMYTINDAHKKGVTAIAATSDCRKVVSGGGEGQVRVWRIEECKVSQANTIPHSHGNRKKSNVKSVVYV----AHMETAMKEH-----ANAVSCIRMNKDDTQCVSSSADGTCIIWCLIKYTRKQIMFANTLFRCVCWRPDECQIITSGTDRKIGYWEVYDGSLIRELEGSRSGSVNGMDITADGDIFVTGGDDKIVKVWKYNEGYVTHVGLGHSMPITRLRISPDRQLITTVSEDGAIYFWKF 2014
            L+L  V+GF G          +   ++Y     +V  D+ T +Q FL GH++ V  +    + + +ASGQ    G +A + +W++    C++ F  H   + SL+FS +   L+ +G    G   VV+W    +T    +      H    + + +V S  ++   V+ G + +RVW L  +N  +R     LG +        + +  + + DD   F  T SG IL ++ K  ++                        +C+G E    +L  L++ R      + G+ DGT+               P   +      L G VS + +   G    AGT   H+ R  +G      +  +    + D        ++    +   + ++   + ++L   +    +  T            G+    +R F    GA +   +  H+  +T +  + +   + S    G + ++    CK      +      R  S   S + V    AH+            A+A S   + + D   V +S+        L +  R            VC+ P   Q++ +    K+ +++   G L++E+   +    + + ++ DG I V    D  ++ W    G      +GHS  + RLR +   +    VS  G I+ W  
Sbjct:  376 LKLRRVVGFGGETNGYALWTRNGATLVYPCHAVIVALDVETSSQHFLTGHSDKVSALAFDGNTEILASGQ---SGPQAIVRIWNFQKGSCLAMFKTHAHSLFSLSFSWSGDVLSGVGRDSHGKTMVVVWDTSGVTHRRDVLILAKAHTGVDV-QTMVISPFDESRLVSCGRDNVRVWRL--QNGSLRSCAVDLGDLHSTEVTDVAFQERSPALDDKRLFACTRSGHILDIDYKHNVVREVTRLRQPPSRSPRERLPDQGASACVGFE---LALTRLAVSRWF---CVTGSEDGTV-----------RVWSPDFSRVLLQTDLGGAVSLLGVSADGRHVLAGTRTGHLARLDVGGRSYATVTRSPVGPLLDFSLDLERQRVAAVSTNGSLTIWDLGTGQQLYEFSGAEDSACTVSCHPQLERFACGFSSGSVRVF-DVVGARLLAQHRQHRGEITGLEFSPNGEHMYSCDARGSLALYS-AICKEHTLVRLLSGVVARGTSYAPSALAVSGDGAHLAFVGPSEFAVTVADARSLCELLRVDVSIVDASSP------TLDQAER------------VCFGP-AGQLLVATASGKVLWFDARTGRLLKEVRDVQGAGCSALQVSEDGAI-VAMASDATLRAWDPGSGLEVQAFVGHSQEVRRLRFT--GRCPGLVSGGGTIFMWDL 1011          

Query: 1220 CYTCDIFKDGTAIITGWDDSKIRAFYPETGALMYTINDAHKKGVTAIAATSDCRKVVSGGGEGQVRVWRIEECKVSQANTIPHSHGNRKKSNVKSVVYVAHMETAMKEHANAVSCIRMNKDDTQCVSSSADGTCIIWCLIKYTRKQIMFANTL-FRCVCWRPDECQIITSGTDRKIGYWEVYDGSLIRELEGSRSGSVNGMDITADGDIFVTGGDDKIVKVWKYNEGYVTHVGLGHSMPITRLRISPDRQLITTVSEDGAIYFWK 2011
              TC     G  +I G  + +++ F   + +L+ TI DAH   + ++  TSD +++V+G  +  V+ W   + KV + + +P +     K+    V+ + H  T   E  + + C+R++ DD     S  D T  ++ L        ++ + L    +    D   IITS  D+ I  W +  G   + L  +   S+  +        F +   D +VK W   +         H   +  L ++ D   + + S D +I  W+
Sbjct:  433 ALTCKFLPGGLLVILGTRNGELQLFDLASSSLLDTIEDAHDAAIWSLDLTSDGKRLVTGSADKTVKFW---DFKV-ENSLVPGT-----KNKFLPVLKLHHDTTL--ELTDDILCVRVSPDDRYLAISLLDNTVKVFFLDSMKFYLSLYGHKLPVLSIDISFDSKMIITSSADKNIKIWGLDFGDCHKSL-FAHQDSIMNVKFLPQSHNFFSCSKDAVVKYWDGEKFECIQKLYAHQSEVWALAVATDGGFVVSSSHDHSIRIWE 685          

Query: 1331 DAHKKGVTAIAATSDCRKVVSGGGEGQVRVWRIE---ECKVSQANT--IPHSHGNRKKSNVKSVVYVAHMETAMKEHANAVSCIRMNKDDTQCVSSSADGTCIIWCLIKY-----------------TRKQIMFANTLFRCVCWRPDECQIITSGTDRKIGYWEVYDGSLIRELE--GSRSGSVNGMDITADGDIFVTGGDDKIVKVWKYNE 1894
            ++ K  +  +  + D +++ +GG +G++R+W I+    C   ++ T  IP                +     +M  H  +++C++ + D     S S D   +IW L +                   RK+++  +   + +CW PD   ++T G DR +  W   +GS   +L+        V G+        F T  DD+ +K+++Y++
Sbjct:   14 ESRKYEIYTVDVSHDGKRLATGGLDGKIRIWSIDSILRCMELESLTPEIPLPQD------------LQMPLCSMSRHTGSITCVKFSPDGKYLASGSDDRILLIWALDEEQSSQPAFGSEHEREHWTVRKRLVAHDNDIQDICWAPDSSILVTVGLDRSVIVW---NGSTFEKLKRFDVHQSLVKGVVFDPANKYFATTSDDRTMKIFRYHK 210          

Query: 1547 ANAVSCIRMNKDDTQCVSSS-ADGTCIIWCLIKYTRKQIMFANTLFRCVCWRPDEC-QIITSGTDRKIGYWEVYDGSLIRELEGSRSGSVNGMDITADGDIFVTGGDDKIVKVWKYNEGYVTHVGLGHSMP-ITRLRISPDRQLITTVSEDGAIYFWK 2011
            A+ ++ ++ N+++T  ++S+ +D + +++ L   +  Q +        +CW P E    +T+  D    Y+++ + S    +      +V  +D +  GD  VTG  DK ++++K N G+   +     M  + +++ S D + I + S+DG +  W+
Sbjct:  219 ADNITSLKFNQNETDILASTGSDNSIVLYDLRTNSPTQKIVQTMRTNAICWNPMEAFNFVTANEDHNAYYYDMRNLSRSLNVFKDHVSAVMDVDFSPTGDEIVTGSYDKSIRIYKTNHGHSREIYHTKRMQHVFQVKYSMDSKYIISGSDDGNVRLWR 376          

Query: 1133 FVTCSFQD--VRVFHSDSQKELLRINIPNMTCYTCDIFKDGTAIITGWDDSKIRAFYPETG--ALMYTINDAHKKGVTAIAATS-DCRKVVSGGGEGQVRVWRIEECKVSQANTIPHSHGNRKKSNVKSVVYVAHMETAMKEHANAVSCIRMNKDDTQCVSSSADGTCIIWCLIKYTRKQ--------------IMFANTLFRCVCWRPDECQIITSGTDRKIGYWEVYDGSLIRELEGSRSGSV-----NGMDITADGDIFVTGGDDKIVKVWKY 1888
            F+    +D  +R++  +++K ++ +       Y+ D F  G  +++G  D  +R +   TG  +L  +I D    GVT +A +  D + + +G  +  VRVW  E   + +     +  G   K +V SVV+                     +D    VS S D +  +W L     K               I   + +      + DE  I++   DR + +W+   G+ +  L+G R+  +     NG  +  + ++F TG  D   ++WKY
Sbjct:  457 FLATGAEDRLIRIWDIENRKIVMILQGHEQDIYSLDYFPSGDKLVSGSGDRTVRIWDLRTGQCSLTLSIED----GVTTVAVSPGDGKYIAAGSLDRAVRVWDSETGFLVERLDSENESGTGHKDSVYSVVFT--------------------RDGQSVVSGSLDRSVKLWNLQNANNKSDSKTPNSGTCEVTYIGHKDFVLSVATTQNDEY-ILSGSKDRGVLFWDKKSGNPLLMLQGHRNSVISVAVANGSPLGPEYNVFATGSGDCKARIWKY 707          

Query: 1679 FRCVCWRPDECQIITSGTDRKIGYWEVYDGSLIRELEGSRSGSVNGMDITADGDIFVTGGDDKIVKVWKYNEGYVTHVGLGHSMPITRLRISP-DRQLITTVSEDGAIYFW 2008
             R VC+ PD   + T   DR I  W++ +  ++  L+G     +  +D    GD  V+G  D+ V++W    G  + + L     +T + +SP D + I   S D A+  W
Sbjct:  446 IRSVCFSPDGKFLATGAEDRLIRIWDIENRKIVMILQGHEQ-DIYSLDYFPSGDKLVSGSGDRTVRIWDLRTGQCS-LTLSIEDGVTTVAVSPGDGKYIAAGSLDRAVRVW 554          

Query: 1520 HMETAMKEHANAVSCIRMNKDDTQCVSSSADGTCIIWCLIKYTRKQIMFA-NTLFRCVCWRPDECQIITSGTDRKIGYWEVYDGSLIRELEGSRSGSVNGMDITADGDIFVTGGDDKIVKVWKYNEGYVTHVGLGHSMPITRLRISPDRQLITTVSEDGAIYFW 2008
            H+ +   +H   +  I+   +  + V ++  G   +W    +T + +M A ++    + +  D   +I+   D  I  W+  + S+++E++ + + S+  M  +++   FVT  DD I+K+W ++ G    V  GH   +      P+  LI + S+D  +  W
Sbjct:   86 HLSSNKVKHV--IPAIQWTPEGRRLVVATYSGEFSLWNASSFTFETLMQAHDSAVTTMKYSHDSDWMISGDADGMIKIWQP-NFSMVKEIDAAHTESIRDMAFSSNDSKFVTCSDDNILKIWNFSNGKQERVLSGHHWDVKSCDWHPEMGLIASASKDNLVKLW 246          

Query:   65 MSGEEVNEINKLELINVIGFNGTILDGLHVHPDRQHIIYGLGCTVVIEDLNTKNQCFLQGHTNNVVCITVSNSGKYIASGQITHMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDGCVVIWSLTKMEPICGSPAQHKSAGITECLVYSNTNDDVFVTAGENTLRVWELDVENRKIRPTECSLGAIKRSIKCITISKDDSVFFCGTSSGDILGVNMKSCLLSCIGPEKETFSLGVLSIIRLING--DLIVGAGDGTICQVKVVEKKEGNKIMPKIVKTSNS--CMLVGGVSSITLRGQGHQFYAGTEKSHIYRFSLGDFKSELINTAHYSAVNDIVYPNNCPKLFVTCSFQDVRVFHSDSQKELLRINIPNMTCYTCDIFKDGTAIITGWDDSKIRAFYPETGALMYTINDAHKKGVTAIAATSDCRKVVSGGGEGQVRVWRIEECKVSQANTIPHSHGNRKKSNVKSVVYVAHMETAMKEHANAVSCIRMNKDDTQCVSSSADGTCIIWCLIKYTRKQIMFANTLFRCVCWRPDECQIITSGTDRKIGYWEVYDGSLIRELEGSRSGSVNGMDITADGDI--FVTGGDDKIVKVWKYNEGYVTHVGLGHSMPITRLRISPDRQLITTVSEDGAIYFWKFP 2017
            MS +E +++ +LEL +VIGF G + +GL VHPDR H+IY LG TVVIE + T  Q  L GHT+NV C+ VS SG+Y+ASGQ  HMG+KA +++WDY  K+     +LHKVKV++LAFSPN++YL SLGGQDDG VV+W L   E +CGSPA   SAG T  + ++N ND++F+T G  TLRVWELD  NRKIRPTEC++G +KR + CI +++DD+ FFCGT+SGDIL +N+++ L    GP KE FS GV + + LI G  +L+VGAGDGT+  V     K         V  +NS  C + G ++SI LRGQGHQF+ GT+ S +YRF+  +F  E INT HY  VND+V+P     +F TCS  ++RV+++++ KELLRI +PN+TC T DI KDG A ++GWDD KIR F PE+G L Y I+DAH KGVTA+   S C K+VSGGGEGQVRVW  ++                             +   MKEH  +V+CI++ +DDT+CVS+S DGTCIIW L  + R QI+FANT+F  VC+ P +CQIIT+GTDRKI YWE +DG+LIR+LEGS +GS+ GMDI  D  +  FVTGG DK++KVW Y+ G VTH+G GHS  ITR++I P+ + I +VS DGAI  W++P
Sbjct:    1 MSNKEASDVGRLELESVIGFAGAVPNGLLVHPDRDHLIYPLGNTVVIEQIKTGKQSCLSGHTDNVTCVAVSKSGRYLASGQQAHMGFKASVIVWDYAEKKLKYQLTLHKVKVEALAFSPNDEYLVSLGGQDDGSVVVWDLQAGEAVCGSPAAVPSAGTTNAVAFANHNDNLFITGGNKTLRVWELDRPNRKIRPTECNMGQLKRIVNCIKVTEDDTHFFCGTTSGDILMINIQNRLFRHYGPAKEKFSQGVTA-MELIKGGQELLVGAGDGTVAVVDCKNFK---------VSKANSKLCKVEGDITSIALRGQGHQFFVGTKLSQMYRFNFPEFTYERINTCHYDKVNDVVFPFGFSDIFATCSKNEIRVWNTNTSKELLRIVVPNVTCNTVDIQKDGKAFVSGWDDGKIRVFRPESGQLFYEISDAHSKGVTAVIVNSTCSKIVSGGGEGQVRVWEGKK-----------------------------LLGMMKEHKGSVTCIKLKRDDTECVSASTDGTCIIWNLESFVRSQIVFANTMFEAVCYHPSDCQIITAGTDRKIAYWETFDGALIRDLEGSSAGSIQGMDIALDDSVTHFVTGGADKLLKVWDYDAGQVTHLGGGHSGDITRVKICPNSRWIVSVSADGAILRWRYP 618          

Query:   98 LELINVIGFNGTILDGLHVHPDRQHIIYGLGCTVVIEDLNTKNQCFLQGHTNNVVCITVSNSGKYI-ASGQITHMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDGCVVIWSLTKMEPICGSPAQHKSAGITECLVYSNTNDDVFVTAGE-NTLRVWELD--VENRKIRPTECSLGA-IKRSIK---------CITISKDDSVFFCGTSSGDILGVNMK--SCLLSCIGPEKETFSLGVLSIIRLIN--GDLIVGAGDGTI---CQVKVVEKK---EGNKIMPKIVKTSNSC--------------MLVGGVSSITLRGQGHQFYAGTEKSHIYRFSLGDFKSELINTAHYSAVNDIVYPNNCPKLFVTCSFQDVRVFHSDSQKELLRINIPNMTCYTCDIFKDGTAIIT----------GWDDSKIRAFYPETGAL-MYTINDAHKKGVTAIAATSDCRKVVSGGGEGQVRV------WRIEECKVSQANTIPHSHGNRKKSNVKSVVYVAHMETAMKEHANAVSCIRMNKDDTQCV--------SSSADGTCIIWCLIKYTRKQIMFANTLFRCVCWRPDECQIITSGTDRKIGYWEVYDGSLIRELEGSRSGSVNGMDITADGDIFVTGGDDKIVKVWKYNEGYVTHVGLGHSMPITRLRISPDRQLITTVSEDGAIYFW 2008
            ++L +V+G+NG   + +    D     Y  G  VVIEDL++  Q  L GH   V  IT  N G  + ++   +     + I +WD   + C    S H  +V  LA+S +++ L S+G   D  VV+W+    + I  S A+     I    ++     + F T GE  ++  W +D  + N  ++  E ++ + +  SIK         C++ +  DSV + G S G +   + +  SC L     + E        I+ LI+  G LI G+  G +     V V E +   E N++  + V  S  C              +L G + S +          GT    ++  +  +  S  + + H   + +IV+  +  K F TC+   V    +    E ++  +   +C          A  T          G+ D  +R F  + G + M+     H   VT I  + D   V+SGG +G + +        +      +   I   H + +      ++++A    A  +   +V     +KD  + V        + + DG  +      Y  +      +L R     PD          R + ++ +    ++R    + +     +DI+  G +   G  ++++K+  YNEG       GHS  ++ +R SP   L+ T S  G +  W
Sbjct:  255 MQLKSVLGYNGAGRNNMVWKYDTGLFAYTSGSIVVIEDLHSGGQKHLIGHVEEVSTITCQNDGLVLASASGSSETSESSQIYIWDIQEETCTKVLSYHPHEVVCLAYSRDDRMLISVGDFRDCSVVVWNTQTYDVITSSYARLPVHDI----LWDPYTVNEFATVGEGGSVMFWLVDETIPNISLKVHEPAVPSELTTSIKPDKPTVHFTCLSYAG-DSVMYAGNSEGVLSAWDTRQNSCFLHWQADKTE--------IVVLISHRGQLIAGSSGGNLRLWSVVGVAEMRLPGENNRLFNETVCVSTLCFRLSSDSLTMEDEMVLDGAIISTSFDDVLETGIVGTASGTLWYINWSERTSIRLVSGHAEQITNIVFSGSDDKYFATCAKDGVLHLWTTDNLEHMQFQVVGQSCNCVAFCPIPPATPTNAIHPSHCAAGYSDGTVRMF--DLGKVEMFMKMQPHACAVTVIGFSVDGHVVISGGSDGVLAISSPSTGLTVRLLNDHKGVPITDLHVSAQYRLTCPLMWLA----ASADSRVSVWSADWSKDFCELVDWLTFPSPAIAPDGKAL---RKSYPGEYSKLPPSLARFSPSDPDIIVFTGYSMQRVVHFYSLAQRKVVR--TAALTHWALSLDISPKGHLIAIGTQERLIKLMDYNEGSFQDF-TGHSDAVSEVRFSPSGHLLYTCSH-GDVLIW 928          

Query: 1157 VRVFHSDSQKELLRINIPNMTCYTCDIFKDGTAIITGWDDSKIRAFYPETGALMYTINDAHKKGVTAIAATSDCRKVVSGGGEGQVRVWRIEECKVSQANTIPHSHGNRKKSNVKSVVYVAHMETAMKEHANAVSCIRMNKDDTQCVSSSADGTCIIWCLIKYTRKQIM--FANTLFRCVCWRPDECQIITSGTDRKIGYWEVYDGSLIRELEGSRSGSVNGMDITADGDIFVTGGDDKIVKVWKYNEGYVTHVGLGHSMPITRLRISPDRQLITTVSEDGAIYFW 2008
            +RV+  ++ KEL ++       YT  +      +++G  D  ++ +  +T +L++T+   HK  V+ +  T D ++++S   +  V++W +E C                               ++  H   V  I +  D  + VS+S D T  IW L  +     +   + T++ CVC  PD+   I+   D  +  W++     +R L G  S  +  + +T DG   ++ GDD  VKVW    G       GHS  +  + +SPD   I + SED     W
Sbjct:   37 IRVWDYETGKELNKLLDHTKLVYTLALSPHADFLVSGAFDHTVKIWDMDTLSLVHTLK-GHKNWVSGVLVTPDSKRIISSSYDKTVKIWDVETCA---------------------------FVNSLDGHDGHVRGIAITSDGRRLVSASQDRTLRIWNLETFAHVSTLRGHSETVY-CVCCSPDDKFAISGSEDTMVKIWDLESAKEVRSLVGHTS-DIFAVAVTPDGSKVISSGDDTQVKVWSLESGEELASLHGHSESVRIVTVSPDGLTIVSGSEDATFKIW 292          

Query: 1373 DCRKVVSGGGEGQVRVWRIEECKVSQANTIPHSHGNRKKSNVKSVVYVAHMETAMKEHANAVSCIRMNKDDTQCVSSSADGTCIIWCLIKYTRKQIMFANTLFRCV-CWRPDECQIITSGTDRKIGYWEVYDGSLIRELEGSRSGSVNGMDITADGDIFVTGGDDKIVKVWKYNEGYVTHVGLGHSMPITRLRISPDRQLITTVSEDGAIYFWKF 2014
            D R+VV+G  +  +R+W +                 R   +++           MK H   V C++   D+ + +S S D T ++W ++K+TR  +++ +    CV C R DE  +++   D  I  W++     +  L+G   G+V+ ++   D    ++G  DK +K+W    G   +   GH+  +T +++    +LI + S DG I FW  
Sbjct:  158 DRRRVVTGSSDRTIRMWDV-----------------RSGRSIRK----------MKGHKGGVRCLQF--DNERIISGSWDMTIMVWHIVKFTRLHVLYGHK--GCVSCLRFDENTLVSGSHDSTIRVWDMRTWECVLVLQG-HEGAVSCLEF--DAPFVLSGSADKTIKLWNVESGDCLNTLRGHADAVTSVKVIG--ELILSGSADGMILFWDL 336          

Query:  881 QVKVVEKKEGNKIMPKIVKTSNSCMLV-----GGVSSITLRGQGHQFYAGTEKSHIYRFSL-GDFKSELINTAHYSAVNDIVYPNNCPKLFVTCSFQDVRVFHSDSQKELLRINIPNMTCYTCDIFKDGTA-IITGWDDSKIRAFYPETGALMYTINDAHKKGVTAIAATSDCRKVVSGGGEGQVRVWRIEECKVSQANTIPHSHGNRKKSNVKSVVYVAHMETAMKEHANAVSCIRMNKDDTQCVSSSADGTCIIW----------CLIKYTRKQIMFANTLFRCVCWRPDECQIITSGTDRKIGYWEVYDGSLIRELEGSRSGSVNGMDITADGDIFVTGGDDK 1867
            Q+ V++ K   + +P       S +++     G + S      G    +      IY +++ G+ ++  +   H  A+ D+ +  +   +F   + + V ++  ++   + R+        +C   + G   +++G DDS I+ +         T  +  +  VTA+A +    ++ SGG + +++VW + +                       V+Y       M  H + V+ ++++ D +  +S+S D T  +W          CL  +   Q  F   L +C  W PD   I     DR +  W+     ++ +L G  +GSVN         I ++ G DK
Sbjct:   27 QLSVIDPKNAIQALPNRTSALESPIMLLTGHEGEIYSSRFHPSGETLASVGFDRLIYLWNVYGECENFAVLKGHTGAIMDVHFSTDGNTMFTASTDKTVALWDYETGARMKRLKGHTSFVNSCCPSRRGMQYVVSGSDDSTIKLWDTRKRGCAQTFQNVFQ--VTAVAFSDASDQIFSGGIDNEIKVWDLRK---------------------NDVLY------KMSGHTDTVTGVQLSPDGSFLLSNSMDNTVRMWDVRAFAPMERCLKVFLGAQHNFEKNLIKC-SWSPDGLMIAAGSADRFVYVWDTNSRRILYKLPG-HAGSVNDAHFHPTEPILLSCGSDK 341          

Query:  122 FNGTILDGLHVHPDRQHIIYGLGCTVVIEDLNTKNQCFLQGHTNNVVCITVSNSGKYIASGQITHMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDGCVVIWSLTKMEPICGSPAQHKSAGITECLV--YSNTNDDVFVTAGENTLRVWELDVENRKIRPTECSLGAIKRSIKCITISKDDSVFFCGTSSGDILGVNMKSCLLSCIGPEKETFSLGVLSIIRLI-NGDLIVGAGDG--TICQVKVVEKKEGNKIMPKIVKTSNSCMLVGGVSSITLRGQGHQFYAGTEKSHIYRFSLGDFKSELINTAHYSAVNDIVYPNNCPKLFVTCSFQDVRVFHSDSQKELLRINIPNMTCYTCDIFKDGTAIITGWDDSKIRAFYPETGALMYTINDAHKKGVTAIAATSDCRKVVSGGGEGQVRVWRIEECKVSQANTIPHSHGNRKKSNVKSVVYVAHMETAMKEHANAVSCIRMNKDDTQCVSSSADGTCIIWCLIKYTRKQIMFANTLFRCVCWRPDECQIITSGTDRKIGYWEVYDGSLIRELEGSRSGSVNGMDITADGDIFVTGGDDKIVKVWKYNEGYVTHVGLGHSMPITRLRISPDRQLITTVSEDGAIYFWKFPN 2020
             +G +  GL +HPD+QH+IY LGCTV++  ++   Q FL GHTNNV C++VS SG YIASGQI  +G+K  + +WDY  +   +   LHK KV+SLAFSPN+KYL SLGGQDD  +V+W++   + ICGS A    A    CLV  YSNT+D+VFV+AG  TLRVWELDV NRKIRPTEC LG ++R+IKC+ IS DD   FCGT+SGDIL VN+++ LLS  GP K   SLGV S++R++ +GDL+VG+G G  T+C       K   K++  I        L  GV+SIT++  G QF+ GTE   IYR S  DFK+E++ T+H SAV D+V P    +LF TCS  D+R++H D  KELLRI +PNMTC   D   DG ++I+ W+D KIRAF PETG LM+TINDAHK GVTAIA T DC+++VSGGG+GQVRVW +          +PH H                +   MKEH   VS +++  +D +CV++S DGTCI+W L ++   Q M ANT+FR +C+ P+E QIITSGTDRKI YW+VYDGS+IRELEGS+SG++N M IT DG  FVTGGDD++V+VW Y EG VTHVG+     IT ++I  + +++ T S DGAI  WKFP+
Sbjct:   34 LSGRVPSGLRLHPDKQHLIYPLGCTVILRSISDDKQEFLHGHTNNVCCLSVSRSGTYIASGQINFLGFKTTVFIWDYAQRSVYAELVLHKAKVESLAFSPNDKYLVSLGGQDDDSIVVWNIETKQAICGSTATSHVA--RHCLVVQYSNTDDNVFVSAGSGTLRVWELDVANRKIRPTECKLGKLQRNIKCVEISNDDQFLFCGTTSGDILKVNLRTGLLSDFGPVKAKHSLGV-SVLRVMESGDLLVGSGSGVLTLCS------KTNFKMLQSI-------QLEKGVTSITIKDTGQQFFVGTEAGLIYRMSSDDFKAEVVFTSHTSAVKDVVMPFGTSELFATCSDDDIRLWHIDKPKELLRIPVPNMTCNALDFMIDGHSLISAWNDCKIRAFGPETGRLMFTINDAHKMGVTAIAGTRDCKRIVSGGGDGQVRVWEL----------LPHCH---------------RLVEIMKEHKATVSSLKIKSNDKECVTASVDGTCIVWDLERFVGLQRMIANTVFRAMCYHPEEHQIITSGTDRKIAYWDVYDGSIIRELEGSQSGAINAMHITKDGGYFVTGGDDRVVRVWSYMEGVVTHVGIAQGGSITSMKICSNNRILVTTSADGAIMQWKFPH 630          

Query:   83 NEINKLELINVIGFNGTILDGLHVHPDRQHIIYGLGCTVVIED-LNTKNQCFLQGHTNNVVCITVSNSGKYIASGQITHMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDGCVVIWSLTKMEPICGSPAQHKSAGITECLVYSNTNDDVFVTAGENTLRVWELDVENRKIRPTECS-----------LGAIKRS----IKCITISKDDSVFFCGTSSGDILGVNMKSCL 772
            N   K+ L  V+G   +   GL   P    I Y  GC VV+ D  N +    +      +  +  S  G+++ +G+  HM     + LWD   ++ V+    HK  V  +AFSPN KY+ S+G Q D  V +W+  KM+ +    A   S+ +T   V  + +   FVT G   ++ W LD      R ++ S           LG ++ +    + C   SK DS  FC TSSG +  +N    L
Sbjct:   30 NLSRKVTLEKVLGVTASGNSGLACDPKSGLIAYPAGCVVVLLDPRNNRQNHIINTSRKAITALAFSPDGRFLVTGESGHM---PAVRLWDVAERRHVAELQEHKYGVSCVAFSPNSKYIVSVGNQHDMMVNVWAW-KMDVVVA--ANKVSSKVTA--VSFSEDRSYFVTVGNRHVKFWYLD----HCRASKVSAPVPLLGRVGLLGELRNNFFCDVACGRGSKCDST-FCITSSGLLCELNRSRTL 262          

Query:   53 KKLRMSGEEVNEINKLELINVIGFNGTILDGLHVHPDRQHIIYGLGCTVVI-EDLNTKNQCFLQGHTNNVVCITVSNSGKYIASGQITHMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDGCVVIWSLTKMEPICGSPAQHKSAGITECLVYSNTNDDVFVTAGENTLRVWELDVENRKIRPTECSLGAIKRSIKCITISKDDSVFFCG---------------TSSGDI----------LGVNMKSCLLSCIGPEKETFSLGVLS-IIRLINGDLIVGAGDGTICQVKVVEKKEGNKIMPKIVKTSNSCMLVGGVSSITLRGQGHQFYAGTEKSHIYRFSLGDFKS-ELINTAHYSAVN--------DIVYPNNCP---KLFVTCSFQD-VRVFHSDSQK-----ELLRI-NI------------PNMTCYTCDIFKDGTAIITGWDDSKIRAFYPETGALMYTINDAHKKGVTAI---AATSDCRKVVSGGGEGQVRVWRIEECKVSQANTIPHSHGNRKKSNVKSVVYVAHMETAMKEHANAVSCIRMNKDDTQCVSSSADGTCIIWCLIKYTRKQIMFANT-LFRCVCWRPDECQIITSGTDRKIGYWEVYDGSLIRELEGSRS--GSVNGMDITADGDIFVTGGDDKIVKVWKYNEGYVTHVGLGHSMPITRLRISPDRQLITTVSEDGAIYFWKF 2014
            ++ R S ++    +++ L  V+G       GL   P+   I Y  G  VV+   L  +    L         +  S+ GK++A+G+    G++  + +W+    Q V+    HK +V  +AFS N  Y+ S+G Q D  V +W   K   +    +   S+G+    V  + +   FVTAG   ++ W LD  +R+ R      G +    +   ++   +  FCG               TSSG +            V++K+   SC+   ++    G    +IR+ + D +      T+ +  ++  ++G       ++ S S  L     ++TL               IY + + D  S E I  A Y + +        +  YP++ P     F++CS  + VR +++ S +     +LLRI N+            P +      +  DG  +  G     +R F  +    +  I +AH   V  +    A++  R + S G +  + V+  +    S   T+     N   +++ +V +     T      + V+C      + Q    +ADG         ++R+  +   T L+   C R    Q + +  DR I  + V  G L R L+GS S  G++  + +   G  F T   +K ++V+ Y  G       GHS  +T LR S D   + + S D  I+ WK 
Sbjct:   65 RQNRQSTQKKTSGSQVILEKVLGITTVSSSGLTSDPNTGLIAYPAGSVVVLLHPLRNQQNHILNWSKKLFTAVAFSHDGKHLATGE---SGHRPCVRVWEVGGSQ-VAEVQSHKHRVSCVAFSSNSGYIVSVGYQHDMTVSVWDWRKGSIVA---SNKVSSGVLS--VSFSQDSSYFVTAGNRHVKFWYLDA-SREQR----VYGTVPLIGRSGLLNDHKTRVFCGVACGRGLMASNTYCVTSSGLLCLFNRVRYLEAWVDLKTSSASCLTVSEDFIFCGCADGVIRVFSPDRLQYL--TTLQRPHLLGAEQG-------LQASVSDALYPPTLALTLDPCNQLLTCVYGDHSIYVWDVHDVHSVEKIYWARYHSSSVWSLEVYPERPYPSHAPLPASSFLSCSSDNTVRFWNAASHRNLCGDDLLRILNLGAAQQGEAVDGKPGVRVLA--VSPDGQHLAVGDRSGDLRVFGLQFLDQLVKI-EAHDLEVLCLEYSPASTGVRLLASAGRDRLIHVFDPDR-NYSLLQTL-----NDHSASISAVRF-----TGESPEVHLVTCSVDKSINFQTAEQTADGP-------GFSRRHCVVEKTSLYDMDCSR---TQAVVACQDRNIRVYGVDSGKLQRCLKGSTSDRGALLKVRMDPSGSFFATSCSNKNIEVFDYETGECVASLFGHSEAVTCLRFSWDCTRLVSASADSCIFVWKL 735          

Query:   56 KLRMSG--EEVNEINKLELINVIGFNGTILDGLHVHPDRQHIIYGLGCTVVIED-LNTKNQCFLQGHTNNVVCITVSNSGKYIASGQITHMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDGCVVIWSLTKMEPICGSPAQHKSAGITECLVYSNTNDDVFVTAGENTLRVWELDVENRKIRPTECSLGAIKRS-------------IKCITISKDDSVFFCGTSSGDILGVNMKSCLLSCIGPEKETFSLGVLSIIRLINGDLIVGAGDGTI 877
            KLR SG   + +  NK+ L  V+G        L   P    + Y  GC VV+ +    K           +  +  S  GKY+ +G+  HM     + +WD   +  VS    HK  V  +AFSPN KY+ S+G + D  V +W+  K   +  +    K   ++    +S+ +   FVTAG   ++ W LD  + K      ++  + RS             + C    +  S  FC TSSG +   N +  L   +  E  T     LS+       +  G  DGT+
Sbjct:   22 KLRRSGARHKRDLSNKVTLEKVLGITAEGNRALACEPRTGLLAYPAGCVVVLLNPRKNKQHHIFNSSRKAITTLAFSPDGKYVVTGESGHM---PAVRVWDVSERLQVSELQEHKYGVACVAFSPNGKYIISVGYEHDMMVNVWNWKKNVVVAANKVSSKVTAVS----FSD-DSSYFVTAGNRHVKFWYLD--HNKTSKVNATVPLLGRSGLLGELRNNFFSDVACGRGRRSSST-FCITSSGLLCEFNERRLLDKWV--ELRTSQATCLSVTEEF---IFCGCSDGTV 295          

Query:   56 KLRMSG--EEVNEINKLELINVIGFNGTILDGLHVHPDRQHIIYGLGCTVVIED-LNTKNQCFLQGHTNNVVCITVSNSGKYIASGQITHMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDGCVVIWSLTKMEPICGSPAQHKSAGITECLVYSNTNDDVFVTAGENTLRVWELDVENRKIRPTECSLGAIKRS-------------IKCITISKDDSVFFCGTSSGDILGVNMKSCLLSCIGPEKETFSLGVLSIIRLINGDLIVGAGDGTI 877
            KLR SG   + +  NK+ L  V+G        L   P    + Y  GC VV+ +    K           +  +  S  GKY+ +G+  HM     + +WD   +  VS    HK  V  +AFSPN KY+ S+G + D  V +W+  K   +  +    K   ++    +S+ +   FVTAG   ++ W LD  + K      ++  + RS             + C    +  S  FC TSSG +   N +  L   +  E  T     LS+       +  G  DGT+
Sbjct:   22 KLRRSGARHKRDLSNKVTLEKVLGITAEGNRALACEPRTGLLAYPAGCVVVLLNPRKNKQHHIFNSSRKAITTLAFSPDGKYVVTGESGHM---PAVRVWDVSERLQVSELQEHKYGVACVAFSPNGKYIISVGYEHDMMVNVWNWKKNVVVAANKVSSKVTAVS----FSD-DSSYFVTAGNRHVKFWYLD--HNKTSKVNATVPLLGRSGLLGELRNNFFSDVACGRGRRSSST-FCITSSGLLCEFNERRLLDKWV--ELRTSQATCLSVTEEF---IFCGCSDGTV 295          

Query:   65 MSGEEVNEINKLELINVIGFNGTILDGLHVHPDRQHIIYGLGCTVVIEDLNTKNQCFLQGHTNNVVCITVSNSGKYIASGQITHMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDGCVVIWSLTKMEPICGSPAQHKSAGITECLVYSNTNDDVFVTAGENTLRVWELDVENRKIRPTECSLGAIKRSIKCITISKDDSVFFCGTSSGDILGVNMKSCLLSCIGPEKETFSLGVLSIIRLINGDLIVGAGDGTICQVKVVEKKEGNKIMPKIVKTSNSCMLVGGVSSITLRGQGHQFYAGTEKSHIYRFSLGDFKSELINTAHYSAVNDIVYPNNCPKLFVTCSFQDVRVFHSDSQKELLRINIPNMTCYTCDIFKDGTAIITGWDDSKIRAFYPETGALMYTINDAHKKGVTAIAATSDCRKVVSGGGEGQVRVWRIEECKVSQANTIPHSHGNRKKSNVKSVVYVAHMETAMKEHANAVSCIRMNKDDTQCVSSSADGTCIIWCLIKYTRKQIMFANTLFRCVCWRPDECQIITSGTDRKIGYWEVYDGSLIRELEGSRSGSVNGMDITADGDIFVTGGDDKIVK 1876
            MSGEEVNEINKLELINVIGFNGTILDGLHVHPDRQHIIYGLGCTVVIEDLNTKNQCFLQGHTNNVVCITVSNSGKYIASGQITHMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDGCVVIWSLTKMEPICGSPAQHKSAGITECLVYSNTNDDVFVTAGENTLRVWELDVENRKIRPTECSLGAIKRSIKCITISKDDSVFFCGTSSGDILGVNMKSCLLSCIGPEKETFSLGVLSIIRLINGDLIVGAGDGTICQVKVVEKKEGNKIMPKI+KTSNSCMLVGGVSSITLRGQGHQFYAGTEKSHIYRFSLGDFKSELINTAHYSAVNDIVYPNNCPKLFVTCSFQDVRVFHSDSQKELLRINIPNMTCYTCDIFKDGTAIITGWDDSKIRAFYPETGALMYTINDAHKKGVTAIAATSDCRKVVSGGGEGQVRVWRIEECKVSQANTIPHSHGNRKKSNVKSVVYVAHMETAMKEHANAVSCIRMNKDDTQCVSSSADGTCIIWCLIKYTRKQIMFANTLFRCVCWRPDECQIITSGTDRKIGYWEVYDGSLIRELEGSRSGSVNGMDITADGDIFVTGGDDKIVK
Sbjct:    1 MSGEEVNEINKLELINVIGFNGTILDGLHVHPDRQHIIYGLGCTVVIEDLNTKNQCFLQGHTNNVVCITVSNSGKYIASGQITHMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDGCVVIWSLTKMEPICGSPAQHKSAGITECLVYSNTNDDVFVTAGENTLRVWELDVENRKIRPTECSLGAIKRSIKCITISKDDSVFFCGTSSGDILGVNMKSCLLSCIGPEKETFSLGVLSIIRLINGDLIVGAGDGTICQVKVVEKKEGNKIMPKIIKTSNSCMLVGGVSSITLRGQGHQFYAGTEKSHIYRFSLGDFKSELINTAHYSAVNDIVYPNNCPKLFVTCSFQDVRVFHSDSQKELLRINIPNMTCYTCDIFKDGTAIITGWDDSKIRAFYPETGALMYTINDAHKKGVTAIAATSDCRKVVSGGGEGQVRVWRIEECKVSQANTIPHSHGNRKKSNVKSVVYVAHMETAMKEHANAVSCIRMNKDDTQCVSSSADGTCIIWCLIKYTRKQIMFANTLFRCVCWRPDECQIITSGTDRKIGYWEVYDGSLIRELEGSRSGSVNGMDITADGDIFVTGGDDKIVK 604          

Query:   65 MSGEEVNEINKLELINVIGFNGTILDGLHVHPDRQHIIYGLGCTVVIEDLNTKNQCFLQGHTNNVVCITVSNSGKYIASGQITHMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDGCVVIWSLTKMEPICGSPAQHKSAGITECLVYSNTNDDVFVTAGENTLRVWELDVENRKIRPTECSLGAIKRSIKCITISKDDSVFFCGTSSGDILGVNMKSCLLSCIGPEKETFSLGVLSIIRLINGDLIVGAGDGTICQVKVVEKKEGNKIMPKIVKTSNSCMLVGGVSSITLRGQGHQFYAGTEKSHIYRFSLGDFKSELINTAHYSAVNDIVYPNNCPKLFVTCSFQDVRVFHSDSQKELLRINIPNMTCYTCDIFKDGTAIITGWDDSKIRAFYPETGALMYTINDAHKKGVTAIAATSDCRKVVSGGGEGQVRVWRIEECKVSQANTIPHSHGNRKKSNVKSVVYVAHMETAMKEHANAVSCIRMNKDDTQCVSSSADGTCIIWCLIKYTRKQIMFANTLFRCVCWRPDECQIITSGTDRKIGYWEVYDGSLIRELEGSRSGSVNGMDITADGDIFVTGGDDKIVKVWKYNEGYVTHVGLGHS--MPITRLRISPDRQL 1969
            MSGEEVNEINKLELINVIGFNGTILDGLHVHPDRQHIIYGLGCTVVIEDLNTKNQCFLQGHTNNVVCITVSNSGKYIASGQITHMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDGCVVIWSLTKMEPICGSPAQHKSAGITECLVYSNTNDDVFVTAGENTLRVWELDVENRKIRPTECSLGAIKRSIKCITISKDDSVFFCGTSSGDILGVNMKSCLLSCIGPEKETFSLGVLSIIRLINGDLIVGAGDGTICQVKVVEKKEGNKIMPKIVKTSNSCMLVGGVSSITLRGQGHQFYAGTEKSHIYRFSLGDFKSELINTAHYSAVNDIVYPNNCPKLFVTCSFQDVRVFHSDSQKELLRINIPNMTCYTCDIFKDGTAIITGWDDSKIRAFYPETGALMYTINDAHKKGVTAIAATSDCRKVVSGGGEGQVRVWRIEECKVSQANTIP                              V+ I  N+   Q            W  IKYTRKQIMFANTLFRCVCWRPDECQIITSGTDRKIGYWEVYDGSLIRELEGSRSGSVNGMDITADGDIFVTGGDDKIVK     + Y+ + G      +P+  L I  + +L
Sbjct:    1 MSGEEVNEINKLELINVIGFNGTILDGLHVHPDRQHIIYGLGCTVVIEDLNTKNQCFLQGHTNNVVCITVSNSGKYIASGQITHMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDGCVVIWSLTKMEPICGSPAQHKSAGITECLVYSNTNDDVFVTAGENTLRVWELDVENRKIRPTECSLGAIKRSIKCITISKDDSVFFCGTSSGDILGVNMKSCLLSCIGPEKETFSLGVLSIIRLINGDLIVGAGDGTICQVKVVEKKEGNKIMPKIVKTSNSCMLVGGVSSITLRGQGHQFYAGTEKSHIYRFSLGDFKSELINTAHYSAVNDIVYPNNCPKLFVTCSFQDVRVFHSDSQKELLRINIPNMTCYTCDIFKDGTAIITGWDDSKIRAFYPETGALMYTINDAHKKGVTAIAATSDCRKVVSGGGEGQVRVWRIEECKVSQANTIP-----------------------------IVTEIGRNQMSNQ------------WS-IKYTRKQIMFANTLFRCVCWRPDECQIITSGTDRKIGYWEVYDGSLIRELEGSRSGSVNGMDITADGDIFVTGGDDKIVK-----KDYIVYKGRLRKAFVPMKNLAIDSNVEL 590          

Query:   65 MSGEEVNEINKLELINVIGFNGTILDGLHVHPDRQHIIYGLGCTVVIEDLNTKNQCFLQGHTNNVVCITVSNSGKYIASGQITHMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDGCVVIWSLTKMEPICGSPAQHKSAGITECLVYSNTNDDVFVTAGENTLRVWELDVENRKIRPTECSLGAIKRSIKCITISKDDSVFFCGTSSGDILGVNMKSCLLSCIGPEKETFSLGVLSIIRLINGDLIVGAGDGTICQVKVVEKKEGNKIMPKIVKTSNSCMLVGGVSSITLRGQGHQFYAGTEKSHIYRFSLGDFKSELINTAHYSAVNDIVYPNNCPKLFVTCSFQDVRVFHSDSQKELLRINIPNMTCYTCDIFKDGTAIITGWDDSKIRAFYPETGALMYTINDAHKKGVTAIAATSDCRKVVSGGGEGQVRVWRIEECKVSQANTIPHSHGNRKKSNVKSVVYVAHMETAMKEHANAVSCIRMNKDDTQCVSSSADGTCIIWCLI 1639
            MSGEEVNEINKLELINVIGFNGTILDGLHVHPDRQHIIYGLGCTVVIEDLNTKNQCFLQGHTNNVVCITVSNSGKYIASGQITHMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDGCVVIWSLTKMEPICGSPAQHKSAGITECLVYSNTNDDVFVTAGENTLRVWELDVENRKIRPTECSLGAIKRSIKCITISKDDSVFFCGTSSGDILGVNMKSCLLSCIGPEKETFSLGVLSIIRLINGDLIVGAGDGTICQVKVVEKKEGNKIMPKI+KTSNSCMLVGGVSSITLRGQGHQFYAGTEKSHIYRFSLGDFKSELINTAHYSAVNDIVYPNNCPKLFVTCSFQDVRVFHSDSQKELLRINIPNMTCYTCDIFKDGTAIITGWDDSKIRAFYPETGALMYTINDAHKKGVTAIAATSDCRKVVSGGGEGQVRVWRIEECKVSQANTIPHSHGNRKKSNVKSVVYVAHMETAMKEHANAVSCIRMNKDDTQCVSSSADGTCIIWCL+
Sbjct:    1 MSGEEVNEINKLELINVIGFNGTILDGLHVHPDRQHIIYGLGCTVVIEDLNTKNQCFLQGHTNNVVCITVSNSGKYIASGQITHMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDGCVVIWSLTKMEPICGSPAQHKSAGITECLVYSNTNDDVFVTAGENTLRVWELDVENRKIRPTECSLGAIKRSIKCITISKDDSVFFCGTSSGDILGVNMKSCLLSCIGPEKETFSLGVLSIIRLINGDLIVGAGDGTICQVKVVEKKEGNKIMPKIIKTSNSCMLVGGVSSITLRGQGHQFYAGTEKSHIYRFSLGDFKSELINTAHYSAVNDIVYPNNCPKLFVTCSFQDVRVFHSDSQKELLRINIPNMTCYTCDIFKDGTAIITGWDDSKIRAFYPETGALMYTINDAHKKGVTAIAATSDCRKVVSGGGEGQVRVWRIEECKVSQANTIPHSHGNRKKSNVKSVVYVAHMETAMKEHANAVSCIRMNKDDTQCVSSSADGTCIIWCLM 525          

Query:   65 MSGEEVNEINKLELINVIGFNGTILDGLHVHPDRQHIIYGLGCTVVIEDLNTKNQCFLQGHTNNVVCITVSNSGKYIASGQITHMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDGCVVIWSLTKMEPICGSPAQHKSAGITECLVYSNTNDDVFVTAGENTLRVWELDVENRKIRPTECSLGAIKRSIKCITISKDDSVFFCGTSSGDILGVNMKSCLLSCIGPEKETFSLGVLSIIRLINGDLIVGAGDGTICQVKVVEKKEGNKIMPKIVKTSNSCMLVGGVSSITLRGQGHQFYAGTEKSHIYRFSLGDFKSELINTAHYSAVNDIVYPNNCPKLFVTCSFQDVRVFHSDSQKELLRINIPNMTCYTCDIFKDGTAIITGWDDSKIRAFYPETGALMYTINDAHKKGVTAIAATSDCRKVVSGGGEGQVRVWRIEECKVSQANTIP 1465
            MSGEEVNEINKLELINVIGFNGTILDGLHVHPDRQHIIYGLGCTVVIEDLNTKNQCFLQGHTNNVVCITVSNSGKYIASGQITHMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDGCVVIWSLTKMEPICGSPAQHKSAGITECLVYSNTNDDVFVTAGENTLRVWELDVENRKIRPTECSLGAIKRSIKCITISKDDSVFFCGTSSGDILGVNMKSCLLSCIGPEKETFSLGVLSIIRLINGDLIVGAGDGTICQVKVVEKKEGNKIMPKIVKTSNSCMLVGGVSSITLRGQGHQFYAGTEKSHIYRFSLGDFKSELINTAHYSAVNDIVYPNNCPKLFVTCSFQDVRVFHSDSQKELLRINIPNMTCYTCDIFKDGTAIITGWDDSKIRAFYPETGALMYTINDAHKKGVTAIAATSDCRKVVSGGGEGQVRVWRIEECKVSQANTIP
Sbjct:    1 MSGEEVNEINKLELINVIGFNGTILDGLHVHPDRQHIIYGLGCTVVIEDLNTKNQCFLQGHTNNVVCITVSNSGKYIASGQITHMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDGCVVIWSLTKMEPICGSPAQHKSAGITECLVYSNTNDDVFVTAGENTLRVWELDVENRKIRPTECSLGAIKRSIKCITISKDDSVFFCGTSSGDILGVNMKSCLLSCIGPEKETFSLGVLSIIRLINGDLIVGAGDGTICQVKVVEKKEGNKIMPKIVKTSNSCMLVGGVSSITLRGQGHQFYAGTEKSHIYRFSLGDFKSELINTAHYSAVNDIVYPNNCPKLFVTCSFQDVRVFHSDSQKELLRINIPNMTCYTCDIFKDGTAIITGWDDSKIRAFYPETGALMYTINDAHKKGVTAIAATSDCRKVVSGGGEGQVRVWRIEECKVSQANTIP 467          

Query:   83 NEINKLELINVIGFNGTILDGLHVHPDRQHIIYGLGCTVVIEDLNTKNQCFLQGHTNN-VVCITVSNSGKYIASGQITHMGYKADIMLWDYVTKQCVSTFSLHKVKVQSLAFSPNEKYLASLGGQDDGCVVIWSLTKMEPICGSPAQHKSAGITECLVYSNTNDDVFVTAGENTLRVWELDVENRKIRPTECSLG 664
            NE N+L L  V GF       + + P    + +  GC VV        Q F+     + +  I  +  GK +A+G+    G    + +W   T   +  FS H  +V +LAFS N +++ S+G Q+D  + +W L     +  S    K   I     +S      FVT G   +R W LD    K + T   LG
Sbjct:   18 NENNQLSLEKVFGFTIQNNAAVSLDPTSGIVAFPAGCVVVGYSAKRSKQFFIHNAVKSPITAIAFNREGKLLATGE---SGKSPKVRIWSVETHSQLFEFSGHNYRVGALAFSHNSRFVVSVGSQEDTSINVWELNTNTKMASSKVTSKVIAI----AFSEAG-QFFVTVGVRHVRFWYLDNSRSKSKATTPLLG 204