Histone deacetylase,putative

Overview
NameHistone deacetylase,putative
Smed IDSMED30019300
Length (bp)3598
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Histone deacetylase,putative (SMED30019300) t-SNE clustered cells

Violin plots show distribution of expression levels for Histone deacetylase,putative (SMED30019300) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Histone deacetylase,putative (SMED30019300) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Histone deacetylase,putative (SMED30019300) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30019300

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 12

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
gutSMED30019300SMESG000006246.1 Contig3291GPL15192PMID:23079596
Forsthoefel et al., 2012
whole organism asexual adult colorimetric in situ hybridization evidence
epidermisSMED30019300SMESG000006246.1 Contig3291GPL15192PMID:23079596
Forsthoefel et al., 2012
whole organism asexual adult colorimetric in situ hybridization evidence
dorsal ventral margin of the whole animalSMED30019300SMESG000006246.1 Contig3291GPL15192PMID:23079596
Forsthoefel et al., 2012
whole organism asexual adult colorimetric in situ hybridization evidence
intestinal phagocyteSMED30019300SMESG000006246.1 Contig3291GPL15192PMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
protonephridiaSMED30019300SMESG000006246.1 dd_Smed_v4_1997_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
whole organism asexual adult single-cell RNA-sequencing evidence
gutSMED30019300SMESG000006246.1 dd_Smed_v4_1997_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
whole organism asexual adult single-cell RNA-sequencing evidence
neuronSMED30019300SMESG000006246.1 dd_Smed_v4_1997_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
whole organism asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30019300SMESG000006246.1 dd_Smed_v4_1997_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
whole organism asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30019300SMESG000006246.1 dd_Smed_v4_1997_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
whole organism asexual adult single-cell RNA-sequencing evidence
epidermal cellSMED30019300SMESG000006246.1 dd_Smed_v4_1997_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
whole organism asexual adult single-cell RNA-sequencing evidence
epidermisSMED30019300SMESG000006246.1 dd_Smed_v4_1997_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017
whole organism asexual adult single-cell RNA-sequencing evidence
dorsal region of the epidermisSMED30019300SMESG000006246.1 dd_Smed_v4_1997_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017
whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Histone deacetylase,putative vs. Ensembl Human
Match: HDAC6 (histone deacetylase 6 [Source:HGNC Symbol;Acc:HGNC:14064])

HSP 1 Score: 602.438 bits (1552), Expect = 0.000e+0
Identity = 315/777 (40.54%), Postives = 454/777 (58.43%), Query Frame = 2
Query:  263 TAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKENDQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMN-ERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINFPINKSG-IEAIRKTLEYQKPYWKCLKFYE 2587
            T  V DEQ+     +WD+ + E P+RL    E + +  LL+ C+  QA+  + E +   HS  ++ L+E TQ M   +L+ L+  +D V+   N+   + +++GS + ++ AVL    +NG  +IRPPGHHA  S   G+C+FN+V +AA+YAQ  +  +++LIVDWDVHHG  TQ+ F     VLY SIHRYE G FWP L+ SN+   G  +G+GY IN+P N+  M ++DY++ F  ++LP+A E+ P+LVL++AGFD+  G P+G M   PA FA +TH LM LA G++++ LEGGY + +L + V  +L TL G   P LE    PC S + ++   L+ L  FW+ L  +         E             + P LPI            L   + + RT             VYD  M NH N   S HPE P+R   I   L +  L  RC  L  R A++ E+   HS  YV  L    +      H     F+SIYI   ++  A L+ G    +++ V S    NG A++RPPGHHAE +   GFCFFN+VA+AA +A T    ++ +ILIVDWDVHHGNGTQH F  + +VLY+SLHRYD+G FFP   +G+ S +G     GF VN+AWN   + D++Y++A+  +V+PI++EFNP+LV+VSAGFDAARGDPLGG  V+PE + ++T +L  LA+G++IL LEGGYNL  IS+ M+ C  SLLG P   +       SG + +I +T++  + YW+ L+  +
Sbjct:   86 TGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHPNSYSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQKHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATPAGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSAQASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPPVLPI------------LTWPVLQSRTG-----------LVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHAL-RILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMK 838          

HSP 2 Score: 270.011 bits (689), Expect = 8.515e-74
Identity = 138/365 (37.81%), Postives = 211/365 (57.81%), Query Frame = 2
Query:  257 NKTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQ-LNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHE 1348
            ++T  VYD+ M+ H N+WD+ + E P R+      + E  L   C+ +  +      +   HS  +V  +  T+ M   +L   SS  D ++   +T   + ++ G+   +++AVL     NG  ++RPPGHHA +  A GFC FN+V +AA++AQ ++    +ILIVDWDVHHGN TQ+ F +   VLY+S+HRY+ G F+P   E     IG   G G+ +N+  N   M ++DYL+ +H ++LPIAYE+NPELVL+SAGFD+A G P G   V P  +AH+TH LM LA GR++++LEGGY + S+ +S+     +L G  PP L     P      +I   ++    +W+SL V   ++ E
Sbjct:  479 SRTGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVEDRE 843          

HSP 3 Score: 128.257 bits (321), Expect = 4.255e-29
Identity = 88/283 (31.10%), Postives = 132/283 (46.64%), Query Frame = 2
Query: 2615 SPNQTNP------AALDNIVQIDT---NTLAESVRQLGIVEVTFQTEQSIEETLSQPRNDTFITEPNSSNPIIHLPPIVSSDNAVEVPATTSINSTTHATQNISANFLSVDQSS---GATPVSANVSRVINEGNSVGLVLQDIMNLSGVSNSDIHHFLGLTSNDPLPERV--YAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQVFCGRFVQAHMMQHFQNTRHAIVLSFVDLSSWCYECDSYVHNECLNHAKREAHIAKFG--VPQP 3415
            +P+QT        A LD     D     TL ++  +  +   T     S         + T   E      +I  P   S+D+  + P T+ +  TT     IS + L     +   G+    A+ S+   E N +G               D+   + +  +  L ++   YAV PL WC HL  V   P+A  +DV   C  C + +ENW+CL+CYQV+CGR++  HM+QH  N+ H +VLS++DLS+WCY C +YVH++ L   K  AH  KFG  +P P
Sbjct:  947 TPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDH--QTPPTSPVQGTT---PQISPSTLIGSLRTLELGSESQGASESQAPGEENLLG---------EAAGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAG-LDVTQPCGDCGTIQENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYVHHQALLDVKNIAHQNKFGEDMPHP 1214          
BLAST of Histone deacetylase,putative vs. Ensembl Human
Match: HDAC6 (histone deacetylase 6 [Source:HGNC Symbol;Acc:HGNC:14064])

HSP 1 Score: 602.438 bits (1552), Expect = 0.000e+0
Identity = 315/777 (40.54%), Postives = 454/777 (58.43%), Query Frame = 2
Query:  263 TAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKENDQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMN-ERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINFPINKSG-IEAIRKTLEYQKPYWKCLKFYE 2587
            T  V DEQ+     +WD+ + E P+RL    E + +  LL+ C+  QA+  + E +   HS  ++ L+E TQ M   +L+ L+  +D V+   N+   + +++GS + ++ AVL    +NG  +IRPPGHHA  S   G+C+FN+V +AA+YAQ  +  +++LIVDWDVHHG  TQ+ F     VLY SIHRYE G FWP L+ SN+   G  +G+GY IN+P N+  M ++DY++ F  ++LP+A E+ P+LVL++AGFD+  G P+G M   PA FA +TH LM LA G++++ LEGGY + +L + V  +L TL G   P LE    PC S + ++   L+ L  FW+ L  +         E             + P LPI            L   + + RT             VYD  M NH N   S HPE P+R   I   L +  L  RC  L  R A++ E+   HS  YV  L    +      H     F+SIYI   ++  A L+ G    +++ V S    NG A++RPPGHHAE +   GFCFFN+VA+AA +A T    ++ +ILIVDWDVHHGNGTQH F  + +VLY+SLHRYD+G FFP   +G+ S +G     GF VN+AWN   + D++Y++A+  +V+PI++EFNP+LV+VSAGFDAARGDPLGG  V+PE + ++T +L  LA+G++IL LEGGYNL  IS+ M+ C  SLLG P   +       SG + +I +T++  + YW+ L+  +
Sbjct:   86 TGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHPNSYSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQKHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATPAGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSAQASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPPVLPI------------LTWPVLQSRTG-----------LVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHAL-RILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMK 838          

HSP 2 Score: 270.011 bits (689), Expect = 8.515e-74
Identity = 138/365 (37.81%), Postives = 211/365 (57.81%), Query Frame = 2
Query:  257 NKTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQ-LNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHE 1348
            ++T  VYD+ M+ H N+WD+ + E P R+      + E  L   C+ +  +      +   HS  +V  +  T+ M   +L   SS  D ++   +T   + ++ G+   +++AVL     NG  ++RPPGHHA +  A GFC FN+V +AA++AQ ++    +ILIVDWDVHHGN TQ+ F +   VLY+S+HRY+ G F+P   E     IG   G G+ +N+  N   M ++DYL+ +H ++LPIAYE+NPELVL+SAGFD+A G P G   V P  +AH+TH LM LA GR++++LEGGY + S+ +S+     +L G  PP L     P      +I   ++    +W+SL V   ++ E
Sbjct:  479 SRTGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVEDRE 843          

HSP 3 Score: 128.257 bits (321), Expect = 4.255e-29
Identity = 88/283 (31.10%), Postives = 132/283 (46.64%), Query Frame = 2
Query: 2615 SPNQTNP------AALDNIVQIDT---NTLAESVRQLGIVEVTFQTEQSIEETLSQPRNDTFITEPNSSNPIIHLPPIVSSDNAVEVPATTSINSTTHATQNISANFLSVDQSS---GATPVSANVSRVINEGNSVGLVLQDIMNLSGVSNSDIHHFLGLTSNDPLPERV--YAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQVFCGRFVQAHMMQHFQNTRHAIVLSFVDLSSWCYECDSYVHNECLNHAKREAHIAKFG--VPQP 3415
            +P+QT        A LD     D     TL ++  +  +   T     S         + T   E      +I  P   S+D+  + P T+ +  TT     IS + L     +   G+    A+ S+   E N +G               D+   + +  +  L ++   YAV PL WC HL  V   P+A  +DV   C  C + +ENW+CL+CYQV+CGR++  HM+QH  N+ H +VLS++DLS+WCY C +YVH++ L   K  AH  KFG  +P P
Sbjct:  947 TPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDH--QTPPTSPVQGTT---PQISPSTLIGSLRTLELGSESQGASESQAPGEENLLG---------EAAGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAG-LDVTQPCGDCGTIQENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYVHHQALLDVKNIAHQNKFGEDMPHP 1214          
BLAST of Histone deacetylase,putative vs. Ensembl Human
Match: HDAC6 (histone deacetylase 6 [Source:HGNC Symbol;Acc:HGNC:14064])

HSP 1 Score: 602.438 bits (1552), Expect = 0.000e+0
Identity = 315/777 (40.54%), Postives = 454/777 (58.43%), Query Frame = 2
Query:  263 TAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKENDQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMN-ERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINFPINKSG-IEAIRKTLEYQKPYWKCLKFYE 2587
            T  V DEQ+     +WD+ + E P+RL    E + +  LL+ C+  QA+  + E +   HS  ++ L+E TQ M   +L+ L+  +D V+   N+   + +++GS + ++ AVL    +NG  +IRPPGHHA  S   G+C+FN+V +AA+YAQ  +  +++LIVDWDVHHG  TQ+ F     VLY SIHRYE G FWP L+ SN+   G  +G+GY IN+P N+  M ++DY++ F  ++LP+A E+ P+LVL++AGFD+  G P+G M   PA FA +TH LM LA G++++ LEGGY + +L + V  +L TL G   P LE    PC S + ++   L+ L  FW+ L  +         E             + P LPI            L   + + RT             VYD  M NH N   S HPE P+R   I   L +  L  RC  L  R A++ E+   HS  YV  L    +      H     F+SIYI   ++  A L+ G    +++ V S    NG A++RPPGHHAE +   GFCFFN+VA+AA +A T    ++ +ILIVDWDVHHGNGTQH F  + +VLY+SLHRYD+G FFP   +G+ S +G     GF VN+AWN   + D++Y++A+  +V+PI++EFNP+LV+VSAGFDAARGDPLGG  V+PE + ++T +L  LA+G++IL LEGGYNL  IS+ M+ C  SLLG P   +       SG + +I +T++  + YW+ L+  +
Sbjct:   86 TGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHPNSYSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQKHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATPAGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSAQASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPPVLPI------------LTWPVLQSRTG-----------LVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHAL-RILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMK 838          

HSP 2 Score: 270.011 bits (689), Expect = 8.515e-74
Identity = 138/365 (37.81%), Postives = 211/365 (57.81%), Query Frame = 2
Query:  257 NKTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQ-LNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHE 1348
            ++T  VYD+ M+ H N+WD+ + E P R+      + E  L   C+ +  +      +   HS  +V  +  T+ M   +L   SS  D ++   +T   + ++ G+   +++AVL     NG  ++RPPGHHA +  A GFC FN+V +AA++AQ ++    +ILIVDWDVHHGN TQ+ F +   VLY+S+HRY+ G F+P   E     IG   G G+ +N+  N   M ++DYL+ +H ++LPIAYE+NPELVL+SAGFD+A G P G   V P  +AH+TH LM LA GR++++LEGGY + S+ +S+     +L G  PP L     P      +I   ++    +W+SL V   ++ E
Sbjct:  479 SRTGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVEDRE 843          

HSP 3 Score: 128.257 bits (321), Expect = 4.255e-29
Identity = 88/283 (31.10%), Postives = 132/283 (46.64%), Query Frame = 2
Query: 2615 SPNQTNP------AALDNIVQIDT---NTLAESVRQLGIVEVTFQTEQSIEETLSQPRNDTFITEPNSSNPIIHLPPIVSSDNAVEVPATTSINSTTHATQNISANFLSVDQSS---GATPVSANVSRVINEGNSVGLVLQDIMNLSGVSNSDIHHFLGLTSNDPLPERV--YAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQVFCGRFVQAHMMQHFQNTRHAIVLSFVDLSSWCYECDSYVHNECLNHAKREAHIAKFG--VPQP 3415
            +P+QT        A LD     D     TL ++  +  +   T     S         + T   E      +I  P   S+D+  + P T+ +  TT     IS + L     +   G+    A+ S+   E N +G               D+   + +  +  L ++   YAV PL WC HL  V   P+A  +DV   C  C + +ENW+CL+CYQV+CGR++  HM+QH  N+ H +VLS++DLS+WCY C +YVH++ L   K  AH  KFG  +P P
Sbjct:  947 TPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDH--QTPPTSPVQGTT---PQISPSTLIGSLRTLELGSESQGASESQAPGEENLLG---------EAAGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAG-LDVTQPCGDCGTIQENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYVHHQALLDVKNIAHQNKFGEDMPHP 1214          
BLAST of Histone deacetylase,putative vs. Ensembl Human
Match: HDAC6 (histone deacetylase 6 [Source:HGNC Symbol;Acc:HGNC:14064])

HSP 1 Score: 602.438 bits (1552), Expect = 0.000e+0
Identity = 315/777 (40.54%), Postives = 454/777 (58.43%), Query Frame = 2
Query:  263 TAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKENDQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMN-ERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINFPINKSG-IEAIRKTLEYQKPYWKCLKFYE 2587
            T  V DEQ+     +WD+ + E P+RL    E + +  LL+ C+  QA+  + E +   HS  ++ L+E TQ M   +L+ L+  +D V+   N+   + +++GS + ++ AVL    +NG  +IRPPGHHA  S   G+C+FN+V +AA+YAQ  +  +++LIVDWDVHHG  TQ+ F     VLY SIHRYE G FWP L+ SN+   G  +G+GY IN+P N+  M ++DY++ F  ++LP+A E+ P+LVL++AGFD+  G P+G M   PA FA +TH LM LA G++++ LEGGY + +L + V  +L TL G   P LE    PC S + ++   L+ L  FW+ L  +         E             + P LPI            L   + + RT             VYD  M NH N   S HPE P+R   I   L +  L  RC  L  R A++ E+   HS  YV  L    +      H     F+SIYI   ++  A L+ G    +++ V S    NG A++RPPGHHAE +   GFCFFN+VA+AA +A T    ++ +ILIVDWDVHHGNGTQH F  + +VLY+SLHRYD+G FFP   +G+ S +G     GF VN+AWN   + D++Y++A+  +V+PI++EFNP+LV+VSAGFDAARGDPLGG  V+PE + ++T +L  LA+G++IL LEGGYNL  IS+ M+ C  SLLG P   +       SG + +I +T++  + YW+ L+  +
Sbjct:   86 TGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHPNSYSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQKHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATPAGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSAQASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPPVLPI------------LTWPVLQSRTG-----------LVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHAL-RILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMK 838          

HSP 2 Score: 270.011 bits (689), Expect = 8.515e-74
Identity = 138/365 (37.81%), Postives = 211/365 (57.81%), Query Frame = 2
Query:  257 NKTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQ-LNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHE 1348
            ++T  VYD+ M+ H N+WD+ + E P R+      + E  L   C+ +  +      +   HS  +V  +  T+ M   +L   SS  D ++   +T   + ++ G+   +++AVL     NG  ++RPPGHHA +  A GFC FN+V +AA++AQ ++    +ILIVDWDVHHGN TQ+ F +   VLY+S+HRY+ G F+P   E     IG   G G+ +N+  N   M ++DYL+ +H ++LPIAYE+NPELVL+SAGFD+A G P G   V P  +AH+TH LM LA GR++++LEGGY + S+ +S+     +L G  PP L     P      +I   ++    +W+SL V   ++ E
Sbjct:  479 SRTGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVEDRE 843          

HSP 3 Score: 128.257 bits (321), Expect = 4.255e-29
Identity = 88/283 (31.10%), Postives = 132/283 (46.64%), Query Frame = 2
Query: 2615 SPNQTNP------AALDNIVQIDT---NTLAESVRQLGIVEVTFQTEQSIEETLSQPRNDTFITEPNSSNPIIHLPPIVSSDNAVEVPATTSINSTTHATQNISANFLSVDQSS---GATPVSANVSRVINEGNSVGLVLQDIMNLSGVSNSDIHHFLGLTSNDPLPERV--YAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQVFCGRFVQAHMMQHFQNTRHAIVLSFVDLSSWCYECDSYVHNECLNHAKREAHIAKFG--VPQP 3415
            +P+QT        A LD     D     TL ++  +  +   T     S         + T   E      +I  P   S+D+  + P T+ +  TT     IS + L     +   G+    A+ S+   E N +G               D+   + +  +  L ++   YAV PL WC HL  V   P+A  +DV   C  C + +ENW+CL+CYQV+CGR++  HM+QH  N+ H +VLS++DLS+WCY C +YVH++ L   K  AH  KFG  +P P
Sbjct:  947 TPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDH--QTPPTSPVQGTT---PQISPSTLIGSLRTLELGSESQGASESQAPGEENLLG---------EAAGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAG-LDVTQPCGDCGTIQENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYVHHQALLDVKNIAHQNKFGEDMPHP 1214          
BLAST of Histone deacetylase,putative vs. Ensembl Human
Match: HDAC6 (histone deacetylase 6 [Source:HGNC Symbol;Acc:HGNC:14064])

HSP 1 Score: 601.668 bits (1550), Expect = 0.000e+0
Identity = 315/777 (40.54%), Postives = 454/777 (58.43%), Query Frame = 2
Query:  263 TAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKENDQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMN-ERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINFPINKSG-IEAIRKTLEYQKPYWKCLKFYE 2587
            T  V DEQ+     +WD+ + E P+RL    E + +  LL+ C+  QA+  + E +   HS  ++ L+E TQ M   +L+ L+  +D V+   N+   + +++GS + ++ AVL    +NG  +IRPPGHHA  S   G+C+FN+V +AA+YAQ  +  +++LIVDWDVHHG  TQ+ F     VLY SIHRYE G FWP L+ SN+   G  +G+GY IN+P N+  M ++DY++ F  ++LP+A E+ P+LVL++AGFD+  G P+G M   PA FA +TH LM LA G++++ LEGGY + +L + V  +L TL G   P LE    PC S + ++   L+ L  FW+ L  +         E             + P LPI            L   + + RT             VYD  M NH N   S HPE P+R   I   L +  L  RC  L  R A++ E+   HS  YV  L    +      H     F+SIYI   ++  A L+ G    +++ V S    NG A++RPPGHHAE +   GFCFFN+VA+AA +A T    ++ +ILIVDWDVHHGNGTQH F  + +VLY+SLHRYD+G FFP   +G+ S +G     GF VN+AWN   + D++Y++A+  +V+PI++EFNP+LV+VSAGFDAARGDPLGG  V+PE + ++T +L  LA+G++IL LEGGYNL  IS+ M+ C  SLLG P   +       SG + +I +T++  + YW+ L+  +
Sbjct:   31 TGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHPNSYSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQKHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATPAGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSAQASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPPVLPI------------LTWPVLQSRTG-----------LVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHAL-RILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMK 783          

HSP 2 Score: 269.626 bits (688), Expect = 8.732e-74
Identity = 138/365 (37.81%), Postives = 211/365 (57.81%), Query Frame = 2
Query:  257 NKTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQ-LNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHE 1348
            ++T  VYD+ M+ H N+WD+ + E P R+      + E  L   C+ +  +      +   HS  +V  +  T+ M   +L   SS  D ++   +T   + ++ G+   +++AVL     NG  ++RPPGHHA +  A GFC FN+V +AA++AQ ++    +ILIVDWDVHHGN TQ+ F +   VLY+S+HRY+ G F+P   E     IG   G G+ +N+  N   M ++DYL+ +H ++LPIAYE+NPELVL+SAGFD+A G P G   V P  +AH+TH LM LA GR++++LEGGY + S+ +S+     +L G  PP L     P      +I   ++    +W+SL V   ++ E
Sbjct:  424 SRTGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVEDRE 788          

HSP 3 Score: 128.642 bits (322), Expect = 3.133e-29
Identity = 88/283 (31.10%), Postives = 132/283 (46.64%), Query Frame = 2
Query: 2615 SPNQTNP------AALDNIVQIDT---NTLAESVRQLGIVEVTFQTEQSIEETLSQPRNDTFITEPNSSNPIIHLPPIVSSDNAVEVPATTSINSTTHATQNISANFLSVDQSS---GATPVSANVSRVINEGNSVGLVLQDIMNLSGVSNSDIHHFLGLTSNDPLPERV--YAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQVFCGRFVQAHMMQHFQNTRHAIVLSFVDLSSWCYECDSYVHNECLNHAKREAHIAKFG--VPQP 3415
            +P+QT        A LD     D     TL ++  +  +   T     S         + T   E      +I  P   S+D+  + P T+ +  TT     IS + L     +   G+    A+ S+   E N +G               D+   + +  +  L ++   YAV PL WC HL  V   P+A  +DV   C  C + +ENW+CL+CYQV+CGR++  HM+QH  N+ H +VLS++DLS+WCY C +YVH++ L   K  AH  KFG  +P P
Sbjct:  892 TPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDH--QTPPTSPVQGTT---PQISPSTLIGSLRTLELGSESQGASESQAPGEENLLG---------EAAGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAG-LDVTQPCGDCGTIQENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYVHHQALLDVKNIAHQNKFGEDMPHP 1159          
BLAST of Histone deacetylase,putative vs. Ensembl Celegans
Match: hda-6 (Histone deacetylase 6 [Source:UniProtKB/Swiss-Prot;Acc:Q20296])

HSP 1 Score: 486.493 bits (1251), Expect = 4.323e-155
Identity = 280/773 (36.22%), Postives = 423/773 (54.72%), Query Frame = 2
Query:  326 ERPDRLRVCYEGICETNLLEDC-IRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKENDQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMN-ERSIHPESPRRTQMIFEFLRDNSLLSRCKQLE-SRLASKDEIGLIHSPNYVESLGNI-CQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRS--ENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSL--------LGYPTNQIINFP--INKSGIEAIRKTLEYQKPYWKCLKFYEPLV 2596
            E  DR+    E + +T +LE C +     EID+  +  +H +S V+ + +++  T   +     ++D VF   N+   +        ++   ++ + A NGF ++RPPGHHA      GFC+FNNV  AA+ A  +   ++ILIVD DVHHG+ TQ  FY+  +VLY SIHR+E G FWP L ES++D+IG+ +G GYN N+ LN+T  T+SDYLSI   ++LP+A +++P  V+ISAGFD+ +G P G M + P  ++H+ + L  LA+GR++V+LEGGY  +    +V   +  L G AP  +E  + P +S  ++  + +  L   W         ++ P    LR       N+  +             E  Q      E    +       +T   ++   + H + E   HPE P RT+ I + LR++ +L +C      R+A+ +EI L+H+   +E L      +   +    E+EFNSIY+ + +   A  + G +L  +DE+    +   N   I+RPPGHHA  +   GFC FNNVA+AA YA  ++    K++LI+DWDVHHGNGTQ  F+ + NV+Y+S+HR+D G F+P       S VG    EG +VN+ ++   + D+EY  AF  ++MPI+++FNPDLV++SAGFDAA  DPLG   VTPE F  MT  L+SLA G++I  LEGGYNL  IS+        L        L     Q    P  I  S I+ IR+    Q+ YW  LK ++ ++
Sbjct:   36 ESSDRILKIKEALTKTKILEKCTVLTNFLEIDDADLEVTHDKSMVKDLMESEKKTQEDINSQCEKYDSVFMTENSMKVAKDGVACVRDLTNRIMANEASNGFAVVRPPGHHADSVSPCGFCLFNNVAQAAEEAFFS-GAERILIVDLDVHHGHGTQRIFYDDKRVLYFSIHRHEHGLFWPHLPESDFDHIGSGKGLGYNANLALNETGCTDSDYLSIIFHVLLPLATQFDPHFVIISAGFDALLGDPLGGMCLTPDGYSHILYHLKSLAQGRMLVVLEGGYNHQISAVAVQRCVRVLLGYAPFSIELNEAPKESTVDSCVSLVSVLRHHWNCF------DYFPSRTSLRLAQWPIVNTKVIYNYDPTTRRADTGEIIQDELASTEFTASDVIPTENMETLIYFNEGDDAHFDLEEDNHPEKPARTRRILKTLRESGVLEKCVDRNCERIATNEEIRLVHTKKMLEHLRTTETMKDEELMEEAEKEFNSIYLTRDTLKVARKAVGAVLQSVDEIFEKDAGQRNALVIVRPPGHHASASKSSGFCIFNNVAVAAKYAQRRHKA--KRVLILDWDVHHGNGTQEIFYEDSNVMYMSIHRHDKGNFYPIGEPKDYSDVGEGAGEGMSVNVPFSGVQMGDNEYQMAFQRVIMPIAYQFNPDLVLISAGFDAAVDDPLGEYKVTPETFALMTYQLSSLAGGRIITVLEGGYNLTSISNSAQAVCEVLQNRSMLRRLREEKEQFATKPQKIESSCIKTIREVCAVQQKYWSILKGFQIII 799          

HSP 2 Score: 242.662 bits (618), Expect = 1.598e-66
Identity = 119/326 (36.50%), Postives = 197/326 (60.43%), Query Frame = 2
Query:  260 KTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEI-DNELIYYSHSQSHVQLIEDTQTMT-AIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRA--KNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKA 1225
            +T   ++E    H ++ ++ + E+P R R   + + E+ +LE C+    + I  NE I   H++  ++ +  T+TM     ++E   + + ++   +T   +  + G+ ++ +  + +  A  +N   ++RPPGHHA  S++SGFCIFNNV +AAKYAQ  +  +++LI+DWDVHHGN TQ  FY  S V+Y+SIHR++ GNF+P     +Y  +G   G G ++N+P +   M +++Y   F  +I+PIAY++NP+LVLISAGFD+A+  P G   V P  FA MT++L  LA GR++ +LEGGY + S+ +S       L  ++
Sbjct:  426 ETLIYFNEGDDAHFDLEEDNHPEKPARTRRILKTLRESGVLEKCVDRNCERIATNEEIRLVHTKKMLEHLRTTETMKDEELMEEAEKEFNSIYLTRDTLKVARKAVGAVLQSVDEIFEKDAGQRNALVIVRPPGHHASASKSSGFCIFNNVAVAAKYAQRRHKAKRVLILDWDVHHGNGTQEIFYEDSNVMYMSIHRHDKGNFYPIGEPKDYSDVGEGAGEGMSVNVPFSGVQMGDNEYQMAFQRVIMPIAYQFNPDLVLISAGFDAAVDDPLGEYKVTPETFALMTYQLSSLAGGRIITVLEGGYNLTSISNSAQAVCEVLQNRS 751          

HSP 3 Score: 235.343 bits (599), Expect = 4.538e-64
Identity = 120/340 (35.29%), Postives = 201/340 (59.12%), Query Frame = 2
Query: 1571 HPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKD-EIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGY-PTNQIINFPINKSGIEAIRKTLEYQKPYWKCLKFY 2584
            HPES  R   I E L    +L +C  L + L   D ++ + H  + V+ L    +++    +   E+++S+++ ++S   A      + ++ + + ++ + NGFA++RPPGHHA+   P GFC FNNVA AA  A    +E   +ILIVD DVHHG+GTQ  F+ +K VLY S+HR+++GLF+P   +     +G     G+N N+A N+    DS+Y+S   ++++P++ +F+P  VI+SAGFDA  GDPLGG+ +TP+ + ++   L SLA G++++ LEGGYN  + +  +  CV  LLGY P +  +N    +S +++    +   + +W C  ++
Sbjct:   34 HPESSDRILKIKEALTKTKILEKCTVLTNFLEIDDADLEVTHDKSMVKDLMESEKKTQEDINSQCEKYDSVFMTENSMKVAKDGVACVRDLTNRIMANEASNGFAVVRPPGHHADSVSPCGFCLFNNVAQAAEEAFFSGAE---RILIVDLDVHHGHGTQRIFYDDKRVLYFSIHRHEHGLFWPHLPESDFDHIGSGKGLGYNANLALNETGCTDSDYLSIIFHVLLPLATQFDPHFVIISAGFDALLGDPLGGMCLTPDGYSHILYHLKSLAQGRMLVVLEGGYNHQISAVAVQRCVRVLLGYAPFSIELNEAPKESTVDSCVSLVSVLRHHWNCFDYF 370          
BLAST of Histone deacetylase,putative vs. Ensembl Celegans
Match: hda-6 (Histone deacetylase 6 [Source:UniProtKB/Swiss-Prot;Acc:Q20296])

HSP 1 Score: 486.493 bits (1251), Expect = 4.323e-155
Identity = 280/773 (36.22%), Postives = 423/773 (54.72%), Query Frame = 2
Query:  326 ERPDRLRVCYEGICETNLLEDC-IRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKENDQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMN-ERSIHPESPRRTQMIFEFLRDNSLLSRCKQLE-SRLASKDEIGLIHSPNYVESLGNI-CQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRS--ENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSL--------LGYPTNQIINFP--INKSGIEAIRKTLEYQKPYWKCLKFYEPLV 2596
            E  DR+    E + +T +LE C +     EID+  +  +H +S V+ + +++  T   +     ++D VF   N+   +        ++   ++ + A NGF ++RPPGHHA      GFC+FNNV  AA+ A  +   ++ILIVD DVHHG+ TQ  FY+  +VLY SIHR+E G FWP L ES++D+IG+ +G GYN N+ LN+T  T+SDYLSI   ++LP+A +++P  V+ISAGFD+ +G P G M + P  ++H+ + L  LA+GR++V+LEGGY  +    +V   +  L G AP  +E  + P +S  ++  + +  L   W         ++ P    LR       N+  +             E  Q      E    +       +T   ++   + H + E   HPE P RT+ I + LR++ +L +C      R+A+ +EI L+H+   +E L      +   +    E+EFNSIY+ + +   A  + G +L  +DE+    +   N   I+RPPGHHA  +   GFC FNNVA+AA YA  ++    K++LI+DWDVHHGNGTQ  F+ + NV+Y+S+HR+D G F+P       S VG    EG +VN+ ++   + D+EY  AF  ++MPI+++FNPDLV++SAGFDAA  DPLG   VTPE F  MT  L+SLA G++I  LEGGYNL  IS+        L        L     Q    P  I  S I+ IR+    Q+ YW  LK ++ ++
Sbjct:   36 ESSDRILKIKEALTKTKILEKCTVLTNFLEIDDADLEVTHDKSMVKDLMESEKKTQEDINSQCEKYDSVFMTENSMKVAKDGVACVRDLTNRIMANEASNGFAVVRPPGHHADSVSPCGFCLFNNVAQAAEEAFFS-GAERILIVDLDVHHGHGTQRIFYDDKRVLYFSIHRHEHGLFWPHLPESDFDHIGSGKGLGYNANLALNETGCTDSDYLSIIFHVLLPLATQFDPHFVIISAGFDALLGDPLGGMCLTPDGYSHILYHLKSLAQGRMLVVLEGGYNHQISAVAVQRCVRVLLGYAPFSIELNEAPKESTVDSCVSLVSVLRHHWNCF------DYFPSRTSLRLAQWPIVNTKVIYNYDPTTRRADTGEIIQDELASTEFTASDVIPTENMETLIYFNEGDDAHFDLEEDNHPEKPARTRRILKTLRESGVLEKCVDRNCERIATNEEIRLVHTKKMLEHLRTTETMKDEELMEEAEKEFNSIYLTRDTLKVARKAVGAVLQSVDEIFEKDAGQRNALVIVRPPGHHASASKSSGFCIFNNVAVAAKYAQRRHKA--KRVLILDWDVHHGNGTQEIFYEDSNVMYMSIHRHDKGNFYPIGEPKDYSDVGEGAGEGMSVNVPFSGVQMGDNEYQMAFQRVIMPIAYQFNPDLVLISAGFDAAVDDPLGEYKVTPETFALMTYQLSSLAGGRIITVLEGGYNLTSISNSAQAVCEVLQNRSMLRRLREEKEQFATKPQKIESSCIKTIREVCAVQQKYWSILKGFQIII 799          

HSP 2 Score: 242.662 bits (618), Expect = 1.598e-66
Identity = 119/326 (36.50%), Postives = 197/326 (60.43%), Query Frame = 2
Query:  260 KTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEI-DNELIYYSHSQSHVQLIEDTQTMT-AIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRA--KNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKA 1225
            +T   ++E    H ++ ++ + E+P R R   + + E+ +LE C+    + I  NE I   H++  ++ +  T+TM     ++E   + + ++   +T   +  + G+ ++ +  + +  A  +N   ++RPPGHHA  S++SGFCIFNNV +AAKYAQ  +  +++LI+DWDVHHGN TQ  FY  S V+Y+SIHR++ GNF+P     +Y  +G   G G ++N+P +   M +++Y   F  +I+PIAY++NP+LVLISAGFD+A+  P G   V P  FA MT++L  LA GR++ +LEGGY + S+ +S       L  ++
Sbjct:  426 ETLIYFNEGDDAHFDLEEDNHPEKPARTRRILKTLRESGVLEKCVDRNCERIATNEEIRLVHTKKMLEHLRTTETMKDEELMEEAEKEFNSIYLTRDTLKVARKAVGAVLQSVDEIFEKDAGQRNALVIVRPPGHHASASKSSGFCIFNNVAVAAKYAQRRHKAKRVLILDWDVHHGNGTQEIFYEDSNVMYMSIHRHDKGNFYPIGEPKDYSDVGEGAGEGMSVNVPFSGVQMGDNEYQMAFQRVIMPIAYQFNPDLVLISAGFDAAVDDPLGEYKVTPETFALMTYQLSSLAGGRIITVLEGGYNLTSISNSAQAVCEVLQNRS 751          

HSP 3 Score: 235.343 bits (599), Expect = 4.538e-64
Identity = 120/340 (35.29%), Postives = 201/340 (59.12%), Query Frame = 2
Query: 1571 HPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKD-EIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGY-PTNQIINFPINKSGIEAIRKTLEYQKPYWKCLKFY 2584
            HPES  R   I E L    +L +C  L + L   D ++ + H  + V+ L    +++    +   E+++S+++ ++S   A      + ++ + + ++ + NGFA++RPPGHHA+   P GFC FNNVA AA  A    +E   +ILIVD DVHHG+GTQ  F+ +K VLY S+HR+++GLF+P   +     +G     G+N N+A N+    DS+Y+S   ++++P++ +F+P  VI+SAGFDA  GDPLGG+ +TP+ + ++   L SLA G++++ LEGGYN  + +  +  CV  LLGY P +  +N    +S +++    +   + +W C  ++
Sbjct:   34 HPESSDRILKIKEALTKTKILEKCTVLTNFLEIDDADLEVTHDKSMVKDLMESEKKTQEDINSQCEKYDSVFMTENSMKVAKDGVACVRDLTNRIMANEASNGFAVVRPPGHHADSVSPCGFCLFNNVAQAAEEAFFSGAE---RILIVDLDVHHGHGTQRIFYDDKRVLYFSIHRHEHGLFWPHLPESDFDHIGSGKGLGYNANLALNETGCTDSDYLSIIFHVLLPLATQFDPHFVIISAGFDALLGDPLGGMCLTPDGYSHILYHLKSLAQGRMLVVLEGGYNHQISAVAVQRCVRVLLGYAPFSIELNEAPKESTVDSCVSLVSVLRHHWNCFDYF 370          
BLAST of Histone deacetylase,putative vs. Ensembl Celegans
Match: hda-6 (Histone deacetylase 6 [Source:UniProtKB/Swiss-Prot;Acc:Q20296])

HSP 1 Score: 484.182 bits (1245), Expect = 3.100e-153
Identity = 282/780 (36.15%), Postives = 424/780 (54.36%), Query Frame = 2
Query:  296 HSNMWDNLYFERPDRLRVCYEGICETNLLEDC-IRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKENDQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMN-ERSIHPESPRRTQMIFEFLRDNSLLSRCKQLE-SRLASKDEIGLIHSPNYVESLGNI-CQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRS--ENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSL--------LGYPTNQIINFP--INKSGIEAIRKTLEYQKPYWKCLKFYE 2587
            H N     + E  DR+    E + +T +LE C +     EID+  +  +H +S V+ + +++  T   +     ++D VF   N+   +        ++   ++ + A NGF ++RPPGHHA      GFC+FNNV  AA+ A  +   ++ILIVD DVHHG+ TQ  FY+  +VLY SIHR+E G FWP L ES++D+IG+ +G GYN N+ LN+T  T+SDYLSI   ++LP+A +++P  V+ISAGFD+ +G P G M + P  ++H+ + L  LA+GR++V+LEGGY  +    +V   +  L G AP  +E  + P +S  ++  + +  L   W         ++ P    LR       N+  +             E  Q      E    +       +T   ++   + H + E   HPE P RT+ I + LR++ +L +C      R+A+ +EI L+H+   +E L      +   +    E+EFNSIY+ + +   A  + G +L  +DE+    +   N   I+RPPGHHA  +   GFC FNNVA+AA YA  ++    K++LI+DWDVHHGNGTQ  F+ + NV+Y+S+HR+D G F+P       S VG    EG +VN+ ++   + D+EY  AF  ++MPI+++FNPDLV++SAGFDAA  DPLG   VTPE F  MT  L+SLA G++I  LEGGYNL  IS+        L        L     Q    P  I  S I+ IR+    Q+ YW  LK ++
Sbjct:   26 HENTVCPTHPESSDRILKIKEALTKTKILEKCTVLTNFLEIDDADLEVTHDKSMVKDLMESEKKTQEDINSQCEKYDSVFMTENSMKVAKDGVACVRDLTNRIMANEASNGFAVVRPPGHHADSVSPCGFCLFNNVAQAAEEAFFS-GAERILIVDLDVHHGHGTQRIFYDDKRVLYFSIHRHEHGLFWPHLPESDFDHIGSGKGLGYNANLALNETGCTDSDYLSIIFHVLLPLATQFDPHFVIISAGFDALLGDPLGGMCLTPDGYSHILYHLKSLAQGRMLVVLEGGYNHQISAVAVQRCVRVLLGYAPFSIELNEAPKESTVDSCVSLVSVLRHHWNCF------DYFPSRTSLRLAQWPIVNTKVIYNYDPTTRRADTGEIIQDELASTEFTASDVIPTENMETLIYFNEGDDAHFDLEEDNHPEKPARTRRILKTLRESGVLEKCVDRNCERIATNEEIRLVHTKKMLEHLRTTETMKDEELMEEAEKEFNSIYLTRDTLKVARKAVGAVLQSVDEIFEKDAGQRNALVIVRPPGHHASASKSSGFCIFNNVAVAAKYAQRRHKA--KRVLILDWDVHHGNGTQEIFYEDSNVMYMSIHRHDKGNFYPIGEPKDYSDVGEGAGEGMSVNVPFSGVQMGDNEYQMAFQRVIMPIAYQFNPDLVLISAGFDAAVDDPLGEYKVTPETFALMTYQLSSLAGGRIITVLEGGYNLTSISNSAQAVCEVLQNRSMLRRLREEKEQFATKPQKIESSCIKTIREVCAVQQKYWSILKGFQ 796          

HSP 2 Score: 242.662 bits (618), Expect = 4.885e-66
Identity = 119/326 (36.50%), Postives = 197/326 (60.43%), Query Frame = 2
Query:  260 KTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEI-DNELIYYSHSQSHVQLIEDTQTMT-AIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRA--KNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKA 1225
            +T   ++E    H ++ ++ + E+P R R   + + E+ +LE C+    + I  NE I   H++  ++ +  T+TM     ++E   + + ++   +T   +  + G+ ++ +  + +  A  +N   ++RPPGHHA  S++SGFCIFNNV +AAKYAQ  +  +++LI+DWDVHHGN TQ  FY  S V+Y+SIHR++ GNF+P     +Y  +G   G G ++N+P +   M +++Y   F  +I+PIAY++NP+LVLISAGFD+A+  P G   V P  FA MT++L  LA GR++ +LEGGY + S+ +S       L  ++
Sbjct:  426 ETLIYFNEGDDAHFDLEEDNHPEKPARTRRILKTLRESGVLEKCVDRNCERIATNEEIRLVHTKKMLEHLRTTETMKDEELMEEAEKEFNSIYLTRDTLKVARKAVGAVLQSVDEIFEKDAGQRNALVIVRPPGHHASASKSSGFCIFNNVAVAAKYAQRRHKAKRVLILDWDVHHGNGTQEIFYEDSNVMYMSIHRHDKGNFYPIGEPKDYSDVGEGAGEGMSVNVPFSGVQMGDNEYQMAFQRVIMPIAYQFNPDLVLISAGFDAAVDDPLGEYKVTPETFALMTYQLSSLAGGRIITVLEGGYNLTSISNSAQAVCEVLQNRS 751          

HSP 3 Score: 112.464 bits (280), Expect = 7.471e-25
Identity = 54/111 (48.65%), Postives = 66/111 (59.46%), Query Frame = 2
Query: 3086 VYAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQVFCGRFVQAHMMQHFQNTRHAIVLSFVDLSSWCYECDSYVHNECLNHAKREAHIAKFGVPQPS 3418
             +AV PL  C HL +V+  P A +I+   +C+ C    E W CLTCY+  CGRFV  H M H  ++ H + LS  DLS WCY CDSYVHN  L  AK  AH +KFG   PS
Sbjct:  846 AHAVVPLATCPHLKEVKPLPPA-KINARTACSECQIGAEVWTCLTCYKYNCGRFVNEHAMMHHLSSSHPMALSMADLSVWCYPCDSYVHNPALIGAKSAAHESKFGETMPS 955          
BLAST of Histone deacetylase,putative vs. Ensembl Celegans
Match: hda-6 (Histone deacetylase 6 [Source:UniProtKB/Swiss-Prot;Acc:Q20296])

HSP 1 Score: 484.182 bits (1245), Expect = 3.100e-153
Identity = 282/780 (36.15%), Postives = 424/780 (54.36%), Query Frame = 2
Query:  296 HSNMWDNLYFERPDRLRVCYEGICETNLLEDC-IRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKENDQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMN-ERSIHPESPRRTQMIFEFLRDNSLLSRCKQLE-SRLASKDEIGLIHSPNYVESLGNI-CQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRS--ENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSL--------LGYPTNQIINFP--INKSGIEAIRKTLEYQKPYWKCLKFYE 2587
            H N     + E  DR+    E + +T +LE C +     EID+  +  +H +S V+ + +++  T   +     ++D VF   N+   +        ++   ++ + A NGF ++RPPGHHA      GFC+FNNV  AA+ A  +   ++ILIVD DVHHG+ TQ  FY+  +VLY SIHR+E G FWP L ES++D+IG+ +G GYN N+ LN+T  T+SDYLSI   ++LP+A +++P  V+ISAGFD+ +G P G M + P  ++H+ + L  LA+GR++V+LEGGY  +    +V   +  L G AP  +E  + P +S  ++  + +  L   W         ++ P    LR       N+  +             E  Q      E    +       +T   ++   + H + E   HPE P RT+ I + LR++ +L +C      R+A+ +EI L+H+   +E L      +   +    E+EFNSIY+ + +   A  + G +L  +DE+    +   N   I+RPPGHHA  +   GFC FNNVA+AA YA  ++    K++LI+DWDVHHGNGTQ  F+ + NV+Y+S+HR+D G F+P       S VG    EG +VN+ ++   + D+EY  AF  ++MPI+++FNPDLV++SAGFDAA  DPLG   VTPE F  MT  L+SLA G++I  LEGGYNL  IS+        L        L     Q    P  I  S I+ IR+    Q+ YW  LK ++
Sbjct:   26 HENTVCPTHPESSDRILKIKEALTKTKILEKCTVLTNFLEIDDADLEVTHDKSMVKDLMESEKKTQEDINSQCEKYDSVFMTENSMKVAKDGVACVRDLTNRIMANEASNGFAVVRPPGHHADSVSPCGFCLFNNVAQAAEEAFFS-GAERILIVDLDVHHGHGTQRIFYDDKRVLYFSIHRHEHGLFWPHLPESDFDHIGSGKGLGYNANLALNETGCTDSDYLSIIFHVLLPLATQFDPHFVIISAGFDALLGDPLGGMCLTPDGYSHILYHLKSLAQGRMLVVLEGGYNHQISAVAVQRCVRVLLGYAPFSIELNEAPKESTVDSCVSLVSVLRHHWNCF------DYFPSRTSLRLAQWPIVNTKVIYNYDPTTRRADTGEIIQDELASTEFTASDVIPTENMETLIYFNEGDDAHFDLEEDNHPEKPARTRRILKTLRESGVLEKCVDRNCERIATNEEIRLVHTKKMLEHLRTTETMKDEELMEEAEKEFNSIYLTRDTLKVARKAVGAVLQSVDEIFEKDAGQRNALVIVRPPGHHASASKSSGFCIFNNVAVAAKYAQRRHKA--KRVLILDWDVHHGNGTQEIFYEDSNVMYMSIHRHDKGNFYPIGEPKDYSDVGEGAGEGMSVNVPFSGVQMGDNEYQMAFQRVIMPIAYQFNPDLVLISAGFDAAVDDPLGEYKVTPETFALMTYQLSSLAGGRIITVLEGGYNLTSISNSAQAVCEVLQNRSMLRRLREEKEQFATKPQKIESSCIKTIREVCAVQQKYWSILKGFQ 796          

HSP 2 Score: 242.662 bits (618), Expect = 4.885e-66
Identity = 119/326 (36.50%), Postives = 197/326 (60.43%), Query Frame = 2
Query:  260 KTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEI-DNELIYYSHSQSHVQLIEDTQTMT-AIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRA--KNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKA 1225
            +T   ++E    H ++ ++ + E+P R R   + + E+ +LE C+    + I  NE I   H++  ++ +  T+TM     ++E   + + ++   +T   +  + G+ ++ +  + +  A  +N   ++RPPGHHA  S++SGFCIFNNV +AAKYAQ  +  +++LI+DWDVHHGN TQ  FY  S V+Y+SIHR++ GNF+P     +Y  +G   G G ++N+P +   M +++Y   F  +I+PIAY++NP+LVLISAGFD+A+  P G   V P  FA MT++L  LA GR++ +LEGGY + S+ +S       L  ++
Sbjct:  426 ETLIYFNEGDDAHFDLEEDNHPEKPARTRRILKTLRESGVLEKCVDRNCERIATNEEIRLVHTKKMLEHLRTTETMKDEELMEEAEKEFNSIYLTRDTLKVARKAVGAVLQSVDEIFEKDAGQRNALVIVRPPGHHASASKSSGFCIFNNVAVAAKYAQRRHKAKRVLILDWDVHHGNGTQEIFYEDSNVMYMSIHRHDKGNFYPIGEPKDYSDVGEGAGEGMSVNVPFSGVQMGDNEYQMAFQRVIMPIAYQFNPDLVLISAGFDAAVDDPLGEYKVTPETFALMTYQLSSLAGGRIITVLEGGYNLTSISNSAQAVCEVLQNRS 751          

HSP 3 Score: 112.464 bits (280), Expect = 7.471e-25
Identity = 54/111 (48.65%), Postives = 66/111 (59.46%), Query Frame = 2
Query: 3086 VYAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQVFCGRFVQAHMMQHFQNTRHAIVLSFVDLSSWCYECDSYVHNECLNHAKREAHIAKFGVPQPS 3418
             +AV PL  C HL +V+  P A +I+   +C+ C    E W CLTCY+  CGRFV  H M H  ++ H + LS  DLS WCY CDSYVHN  L  AK  AH +KFG   PS
Sbjct:  846 AHAVVPLATCPHLKEVKPLPPA-KINARTACSECQIGAEVWTCLTCYKYNCGRFVNEHAMMHHLSSSHPMALSMADLSVWCYPCDSYVHNPALIGAKSAAHESKFGETMPS 955          
BLAST of Histone deacetylase,putative vs. Ensembl Celegans
Match: hda-6 (Histone deacetylase 6 [Source:UniProtKB/Swiss-Prot;Acc:Q20296])

HSP 1 Score: 481.871 bits (1239), Expect = 2.464e-152
Identity = 285/783 (36.40%), Postives = 427/783 (54.53%), Query Frame = 2
Query:  296 HSNMWDNLYFERPDRLRVCYEGICETNLLEDC-IRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVF---FDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKENDQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMN-ERSIHPESPRRTQMIFEFLRDNSLLSRCKQLE-SRLASKDEIGLIHSPNYVESLGNI-CQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRS--ENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSL--------LGYPTNQIINFP--INKSGIEAIRKTLEYQKPYWKCLKFYE 2587
            H N     + E  DR+    E + +T +LE C +     EID+  +  +H +S V+ + +++  T   +     ++D VF   F N+ K+A         ++   ++ + A NGF ++RPPGHHA      GFC+FNNV  AA+ A  +   ++ILIVD DVHHG+ TQ  FY+  +VLY SIHR+E G FWP L ES++D+IG+ +G GYN N+ LN+T  T+SDYLSI   ++LP+A +++P  V+ISAGFD+ +G P G M + P  ++H+ + L  LA+GR++V+LEGGY  +    +V   +  L G AP  +E  + P +S  ++  + +  L   W         ++ P    LR       N+  +             E  Q      E    +       +T   ++   + H + E   HPE P RT+ I + LR++ +L +C      R+A+ +EI L+H+   +E L      +   +    E+EFNSIY+ + +   A  + G +L  +DE+    +   N   I+RPPGHHA  +   GFC FNNVA+AA YA  ++    K++LI+DWDVHHGNGTQ  F+ + NV+Y+S+HR+D G F+P       S VG    EG +VN+ ++   + D+EY  AF  ++MPI+++FNPDLV++SAGFDAA  DPLG   VTPE F  MT  L+SLA G++I  LEGGYNL  IS+        L        L     Q    P  I  S I+ IR+    Q+ YW  LK ++
Sbjct:   26 HENTVCPTHPESSDRILKIKEALTKTKILEKCTVLTNFLEIDDADLEVTHDKSMVKDLMESEKKTQEDINSQCEKYDSVFMTEFQNSMKVAK-DGVACVRDLTNRIMANEASNGFAVVRPPGHHADSVSPCGFCLFNNVAQAAEEAFFS-GAERILIVDLDVHHGHGTQRIFYDDKRVLYFSIHRHEHGLFWPHLPESDFDHIGSGKGLGYNANLALNETGCTDSDYLSIIFHVLLPLATQFDPHFVIISAGFDALLGDPLGGMCLTPDGYSHILYHLKSLAQGRMLVVLEGGYNHQISAVAVQRCVRVLLGYAPFSIELNEAPKESTVDSCVSLVSVLRHHWNCF------DYFPSRTSLRLAQWPIVNTKVIYNYDPTTRRADTGEIIQDELASTEFTASDVIPTENMETLIYFNEGDDAHFDLEEDNHPEKPARTRRILKTLRESGVLEKCVDRNCERIATNEEIRLVHTKKMLEHLRTTETMKDEELMEEAEKEFNSIYLTRDTLKVARKAVGAVLQSVDEIFEKDAGQRNALVIVRPPGHHASASKSSGFCIFNNVAVAAKYAQRRHKA--KRVLILDWDVHHGNGTQEIFYEDSNVMYMSIHRHDKGNFYPIGEPKDYSDVGEGAGEGMSVNVPFSGVQMGDNEYQMAFQRVIMPIAYQFNPDLVLISAGFDAAVDDPLGEYKVTPETFALMTYQLSSLAGGRIITVLEGGYNLTSISNSAQAVCEVLQNRSMLRRLREEKEQFATKPQKIESSCIKTIREVCAVQQKYWSILKGFQ 798          

HSP 2 Score: 242.276 bits (617), Expect = 6.159e-66
Identity = 119/326 (36.50%), Postives = 197/326 (60.43%), Query Frame = 2
Query:  260 KTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEI-DNELIYYSHSQSHVQLIEDTQTMT-AIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRA--KNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKA 1225
            +T   ++E    H ++ ++ + E+P R R   + + E+ +LE C+    + I  NE I   H++  ++ +  T+TM     ++E   + + ++   +T   +  + G+ ++ +  + +  A  +N   ++RPPGHHA  S++SGFCIFNNV +AAKYAQ  +  +++LI+DWDVHHGN TQ  FY  S V+Y+SIHR++ GNF+P     +Y  +G   G G ++N+P +   M +++Y   F  +I+PIAY++NP+LVLISAGFD+A+  P G   V P  FA MT++L  LA GR++ +LEGGY + S+ +S       L  ++
Sbjct:  428 ETLIYFNEGDDAHFDLEEDNHPEKPARTRRILKTLRESGVLEKCVDRNCERIATNEEIRLVHTKKMLEHLRTTETMKDEELMEEAEKEFNSIYLTRDTLKVARKAVGAVLQSVDEIFEKDAGQRNALVIVRPPGHHASASKSSGFCIFNNVAVAAKYAQRRHKAKRVLILDWDVHHGNGTQEIFYEDSNVMYMSIHRHDKGNFYPIGEPKDYSDVGEGAGEGMSVNVPFSGVQMGDNEYQMAFQRVIMPIAYQFNPDLVLISAGFDAAVDDPLGEYKVTPETFALMTYQLSSLAGGRIITVLEGGYNLTSISNSAQAVCEVLQNRS 753          

HSP 3 Score: 112.464 bits (280), Expect = 8.087e-25
Identity = 54/111 (48.65%), Postives = 66/111 (59.46%), Query Frame = 2
Query: 3086 VYAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQVFCGRFVQAHMMQHFQNTRHAIVLSFVDLSSWCYECDSYVHNECLNHAKREAHIAKFGVPQPS 3418
             +AV PL  C HL +V+  P A +I+   +C+ C    E W CLTCY+  CGRFV  H M H  ++ H + LS  DLS WCY CDSYVHN  L  AK  AH +KFG   PS
Sbjct:  848 AHAVVPLATCPHLKEVKPLPPA-KINARTACSECQIGAEVWTCLTCYKYNCGRFVNEHAMMHHLSSSHPMALSMADLSVWCYPCDSYVHNPALIGAKSAAHESKFGETMPS 957          
BLAST of Histone deacetylase,putative vs. Ensembl Fly
Match: HDAC6 (gene:FBgn0026428 transcript:FBtr0307384)

HSP 1 Score: 662.144 bits (1707), Expect = 0.000e+0
Identity = 336/801 (41.95%), Postives = 488/801 (60.92%), Query Frame = 2
Query:  263 TAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQ-LKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGK-APPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVA---------DNHEPYPEYLRHLPESTWNSSKVP--KLPIEDN-----PNKCKENDQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMN-ERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLG--YPTNQIINFPINK-------SGIEAIRKTLEYQKPYWKCLKF 2581
            TA +YDE M  H  +WD  ++E P+R     E   E NL E C+ + ++    + I   H++ H + +++T  +   + ++ELSS++D ++   +T   S +++GSTIE++  ++  +A+NG  +IRPPGHHAM++E +G+C FNNV +A ++A   +  Q+ILI+D+DVHHG  TQ  FYN  +V+Y SIHR+E G+FWP L ES+Y  IG+  G GYN N+PLN T MTN DYL+IF  ++LP+A E+ PEL+++SAG+D+A+GCPEG M+V PAC+ H+ + L+ LA  RV V+LEGGYC++SL +   LTL +L G   PP +E    P   + + + +C+      W+ L +            D  E     LRH     W     P  + P  D      P K   N     ++  LR +   +    K C+ YD +M  H N   + HPE P R Q I +   D  LL + KQL  R A+ DE+ L H+  +V ++  +    P   H     +NS+Y++  ++  A L+ GL+L  +D V    S +G   +RPPGHHAE ++P GFC FNNVAIAA YA+  +   ++++LIVDWDVHHGNGTQH F +N  VLYISLHRY++G FFP   DG+   VG     GFNVNI WNK+ + D EY  AF  ++MPI++EFNP LV+VSAGFDAA GDPLGG  VT E +G +T  L++LA+G++I+ LEGGYN+N IS  M+ C  +LLG   PT Q+    + K       S +E++++ L+ Q+ +W+ L+F
Sbjct:  113 TALIYDESMSQHCCLWDKEHYECPERFTRVLERCRELNLTERCLELPSRSATKDEILRLHTEEHFERLKETSGIRDDERMEELSSRYDSIYIHPSTFELSLLASGSTIELVDHLVAGKAQNGMAIIRPPGHHAMKAEYNGYCFFNNVALATQHALDVHKLQRILIIDYDVHHGQGTQRFFYNDPRVVYFSIHRFEHGSFWPHLHESDYHAIGSGAGTGYNFNVPLNATGMTNGDYLAIFQQLLLPVALEFQPELIIVSAGYDAALGCPEGEMEVTPACYPHLLNPLLRLADARVAVVLEGGYCLDSLAEGAALTLRSLLGDPCPPLVETVPLPRAELAQALLSCIAVHRPHWRCLQLQQTYDCVELQDRDKEEDLHTVLRH-----WIGGPPPMDRYPTRDTAIPLPPEKLTSNAA---RLQVLRAETKLSVPSFKVCYAYDAQMLLHCNLNDTGHPEQPSRIQHIHKMHDDYGLLKQMKQLSPRAATTDEVCLAHTRAHVNTVRRLLGREPKELHDAAGIYNSVYLHPRTFDCATLAAGLVLQAVDSVLRGESRSGICNVRPPGHHAEQDHPHGFCIFNNVAIAAQYAIRDF--GLERVLIVDWDVHHGNGTQHIFESNPKVLYISLHRYEHGSFFPKGPDGNFDVVGKGAGRGFNVNIPWNKKGMGDLEYALAFQQLIMPIAYEFNPQLVLVSAGFDAAIGDPLGGCKVTAEGYGMLTHWLSALASGRIIVCLEGGYNVNSISYAMTMCTKTLLGDPVPTPQLGATALQKPPTVAFQSCVESLQQCLQVQRNHWRSLEF 903          

HSP 2 Score: 283.878 bits (725), Expect = 1.572e-79
Identity = 160/463 (34.56%), Postives = 248/463 (53.56%), Query Frame = 2
Query:  236 ELRINFPN-KTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLE----KFDEP----CDSVKETIQNCLKFLHFFWKSLS-----------VNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKE--------------NDQLNHKIYELRTKNAFNNYPNKTC 1522
            E +++ P+ K  + YD QMLLH N+ D  + E+P R++  ++   +  LL+   ++  +    + +  +H+++HV  +         +L + +  ++ V+    T   + ++AG  ++ + +VL   +++G C +RPPGHHA +    GFCIFNNV IAA+YA  ++  +++LIVDWDVHHGN TQ+ F +  KVLYIS+HRYE G+F+PK  + N+D +G   GRG+N+NIP NK  M + +Y   F  +I+PIAYE+NP+LVL+SAGFD+AIG P G   V    +  +TH L  LA GR++V LEGGY + S+  ++ +   TL G   P  +       +P      S  E++Q CL+     W+SL            V   +N +     LRHL  S  +++        D P+   E              +D L      L     F  YP KTC
Sbjct:  531 ETKLSVPSFKVCYAYDAQMLLHCNLNDTGHPEQPSRIQHIHKMHDDYGLLKQMKQLSPRAATTDEVCLAHTRAHVNTVRRLLGREPKELHDAAGIYNSVYLHPRTFDCATLAAGLVLQAVDSVLRGESRSGICNVRPPGHHAEQDHPHGFCIFNNVAIAAQYAIRDFGLERVLIVDWDVHHGNGTQHIFESNPKVLYISLHRYEHGSFFPKGPDGNFDVVGKGAGRGFNVNIPWNKKGMGDLEYALAFQQLIMPIAYEFNPQLVLVSAGFDAAIGDPLGGCKVTAEGYGMLTHWLSALASGRIIVCLEGGYNVNSISYAMTMCTKTLLGDPVPTPQLGATALQKPPTVAFQSCVESLQQCLQVQRNHWRSLEFVGRRLPRDPVVGENNNEDFLTASLRHLNISNDDATAAAGGLAGDRPDCGDERPSGSKPKVKVKTLSDYLAENKEALEQSEMFAVYPLKTC 993          

HSP 3 Score: 245.743 bits (626), Expect = 1.150e-66
Identity = 130/366 (35.52%), Postives = 220/366 (60.11%), Query Frame = 2
Query: 1517 TCFVYDCRMENH--MNERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIY--HLFEE---EFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQII-NFPINKSGI-EAIRKTLEYQKPYWKCLKFYE 2587
            T  +YD  M  H  + ++  H E P R   + E  R+ +L  RC +L SR A+KDEI  +H+  + E L    +E+  I      EE    ++SIYI+  ++  +LL+ G  + ++D + + +++NG AIIRPPGHHA      G+CFFNNVA+A  +AL  +   +++ILI+D+DVHHG GTQ  F+ +  V+Y S+HR+++G F+P   +    A+G     G+N N+  N   + + +Y++ F  +++P++ EF P+L+IVSAG+DAA G P G + VTP C+ ++   L  LA+ +V + LEGGY L+ +++  +  + SLLG P   ++   P+ ++ + +A+   +   +P+W+CL+  +
Sbjct:  113 TALIYDESMSQHCCLWDKE-HYECPERFTRVLERCRELNLTERCLELPSRSATKDEILRLHTEEHFERL----KETSGIRDDERMEELSSRYDSIYIHPSTFELSLLASGSTIELVDHLVAGKAQNGMAIIRPPGHHAMKAEYNGYCFFNNVALATQHALDVHK--LQRILIIDYDVHHGQGTQRFFYNDPRVVYFSIHRFEHGSFWPHLHESDYHAIGSGAGTGYNFNVPLNATGMTNGDYLAIFQQLLLPVALEFQPELIIVSAGYDAALGCPEGEMEVTPACYPHLLNPLLRLADARVAVVLEGGYCLDSLAEGAALTLRSLLGDPCPPLVETVPLPRAELAQALLSCIAVHRPHWRCLQLQQ 471          
BLAST of Histone deacetylase,putative vs. Ensembl Fly
Match: HDAC6 (gene:FBgn0026428 transcript:FBtr0301774)

HSP 1 Score: 660.988 bits (1704), Expect = 0.000e+0
Identity = 336/801 (41.95%), Postives = 488/801 (60.92%), Query Frame = 2
Query:  263 TAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQ-LKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGK-APPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVA---------DNHEPYPEYLRHLPESTWNSSKVP--KLPIEDN-----PNKCKENDQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMN-ERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLG--YPTNQIINFPINK-------SGIEAIRKTLEYQKPYWKCLKF 2581
            TA +YDE M  H  +WD  ++E P+R     E   E NL E C+ + ++    + I   H++ H + +++T  +   + ++ELSS++D ++   +T   S +++GSTIE++  ++  +A+NG  +IRPPGHHAM++E +G+C FNNV +A ++A   +  Q+ILI+D+DVHHG  TQ  FYN  +V+Y SIHR+E G+FWP L ES+Y  IG+  G GYN N+PLN T MTN DYL+IF  ++LP+A E+ PEL+++SAG+D+A+GCPEG M+V PAC+ H+ + L+ LA  RV V+LEGGYC++SL +   LTL +L G   PP +E    P   + + + +C+      W+ L +            D  E     LRH     W     P  + P  D      P K   N     ++  LR +   +    K C+ YD +M  H N   + HPE P R Q I +   D  LL + KQL  R A+ DE+ L H+  +V ++  +    P   H     +NS+Y++  ++  A L+ GL+L  +D V    S +G   +RPPGHHAE ++P GFC FNNVAIAA YA+  +   ++++LIVDWDVHHGNGTQH F +N  VLYISLHRY++G FFP   DG+   VG     GFNVNI WNK+ + D EY  AF  ++MPI++EFNP LV+VSAGFDAA GDPLGG  VT E +G +T  L++LA+G++I+ LEGGYN+N IS  M+ C  +LLG   PT Q+    + K       S +E++++ L+ Q+ +W+ L+F
Sbjct:   31 TALIYDESMSQHCCLWDKEHYECPERFTRVLERCRELNLTERCLELPSRSATKDEILRLHTEEHFERLKETSGIRDDERMEELSSRYDSIYIHPSTFELSLLASGSTIELVDHLVAGKAQNGMAIIRPPGHHAMKAEYNGYCFFNNVALATQHALDVHKLQRILIIDYDVHHGQGTQRFFYNDPRVVYFSIHRFEHGSFWPHLHESDYHAIGSGAGTGYNFNVPLNATGMTNGDYLAIFQQLLLPVALEFQPELIIVSAGYDAALGCPEGEMEVTPACYPHLLNPLLRLADARVAVVLEGGYCLDSLAEGAALTLRSLLGDPCPPLVETVPLPRAELAQALLSCIAVHRPHWRCLQLQQTYDCVELQDRDKEEDLHTVLRH-----WIGGPPPMDRYPTRDTAIPLPPEKLTSNAA---RLQVLRAETKLSVPSFKVCYAYDAQMLLHCNLNDTGHPEQPSRIQHIHKMHDDYGLLKQMKQLSPRAATTDEVCLAHTRAHVNTVRRLLGREPKELHDAAGIYNSVYLHPRTFDCATLAAGLVLQAVDSVLRGESRSGICNVRPPGHHAEQDHPHGFCIFNNVAIAAQYAIRDF--GLERVLIVDWDVHHGNGTQHIFESNPKVLYISLHRYEHGSFFPKGPDGNFDVVGKGAGRGFNVNIPWNKKGMGDLEYALAFQQLIMPIAYEFNPQLVLVSAGFDAAIGDPLGGCKVTAEGYGMLTHWLSALASGRIIVCLEGGYNVNSISYAMTMCTKTLLGDPVPTPQLGATALQKPPTVAFQSCVESLQQCLQVQRNHWRSLEF 821          

HSP 2 Score: 283.108 bits (723), Expect = 4.291e-80
Identity = 141/371 (38.01%), Postives = 222/371 (59.84%), Query Frame = 2
Query:  236 ELRINFPN-KTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLE----KFDEP----CDSVKETIQNCLKFLHFFWKSL 1321
            E +++ P+ K  + YD QMLLH N+ D  + E+P R++  ++   +  LL+   ++  +    + +  +H+++HV  +         +L + +  ++ V+    T   + ++AG  ++ + +VL   +++G C +RPPGHHA +    GFCIFNNV IAA+YA  ++  +++LIVDWDVHHGN TQ+ F +  KVLYIS+HRYE G+F+PK  + N+D +G   GRG+N+NIP NK  M + +Y   F  +I+PIAYE+NP+LVL+SAGFD+AIG P G   V    +  +TH L  LA GR++V LEGGY + S+  ++ +   TL G   P  +       +P      S  E++Q CL+     W+SL
Sbjct:  449 ETKLSVPSFKVCYAYDAQMLLHCNLNDTGHPEQPSRIQHIHKMHDDYGLLKQMKQLSPRAATTDEVCLAHTRAHVNTVRRLLGREPKELHDAAGIYNSVYLHPRTFDCATLAAGLVLQAVDSVLRGESRSGICNVRPPGHHAEQDHPHGFCIFNNVAIAAQYAIRDFGLERVLIVDWDVHHGNGTQHIFESNPKVLYISLHRYEHGSFFPKGPDGNFDVVGKGAGRGFNVNIPWNKKGMGDLEYALAFQQLIMPIAYEFNPQLVLVSAGFDAAIGDPLGGCKVTAEGYGMLTHWLSALASGRIIVCLEGGYNVNSISYAMTMCTKTLLGDPVPTPQLGATALQKPPTVAFQSCVESLQQCLQVQRNHWRSL 819          

HSP 3 Score: 244.973 bits (624), Expect = 4.041e-67
Identity = 130/366 (35.52%), Postives = 220/366 (60.11%), Query Frame = 2
Query: 1517 TCFVYDCRMENH--MNERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIY--HLFEE---EFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQII-NFPINKSGI-EAIRKTLEYQKPYWKCLKFYE 2587
            T  +YD  M  H  + ++  H E P R   + E  R+ +L  RC +L SR A+KDEI  +H+  + E L    +E+  I      EE    ++SIYI+  ++  +LL+ G  + ++D + + +++NG AIIRPPGHHA      G+CFFNNVA+A  +AL  +   +++ILI+D+DVHHG GTQ  F+ +  V+Y S+HR+++G F+P   +    A+G     G+N N+  N   + + +Y++ F  +++P++ EF P+L+IVSAG+DAA G P G + VTP C+ ++   L  LA+ +V + LEGGY L+ +++  +  + SLLG P   ++   P+ ++ + +A+   +   +P+W+CL+  +
Sbjct:   31 TALIYDESMSQHCCLWDKE-HYECPERFTRVLERCRELNLTERCLELPSRSATKDEILRLHTEEHFERL----KETSGIRDDERMEELSSRYDSIYIHPSTFELSLLASGSTIELVDHLVAGKAQNGMAIIRPPGHHAMKAEYNGYCFFNNVALATQHALDVHK--LQRILIIDYDVHHGQGTQRFFYNDPRVVYFSIHRFEHGSFWPHLHESDYHAIGSGAGTGYNFNVPLNATGMTNGDYLAIFQQLLLPVALEFQPELIIVSAGYDAALGCPEGEMEVTPACYPHLLNPLLRLADARVAVVLEGGYCLDSLAEGAALTLRSLLGDPCPPLVETVPLPRAELAQALLSCIAVHRPHWRCLQLQQ 389          
BLAST of Histone deacetylase,putative vs. Ensembl Fly
Match: HDAC6 (gene:FBgn0026428 transcript:FBtr0074009)

HSP 1 Score: 660.603 bits (1703), Expect = 0.000e+0
Identity = 336/801 (41.95%), Postives = 488/801 (60.92%), Query Frame = 2
Query:  263 TAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQ-LKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGK-APPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVA---------DNHEPYPEYLRHLPESTWNSSKVP--KLPIEDN-----PNKCKENDQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMN-ERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLG--YPTNQIINFPINK-------SGIEAIRKTLEYQKPYWKCLKF 2581
            TA +YDE M  H  +WD  ++E P+R     E   E NL E C+ + ++    + I   H++ H + +++T  +   + ++ELSS++D ++   +T   S +++GSTIE++  ++  +A+NG  +IRPPGHHAM++E +G+C FNNV +A ++A   +  Q+ILI+D+DVHHG  TQ  FYN  +V+Y SIHR+E G+FWP L ES+Y  IG+  G GYN N+PLN T MTN DYL+IF  ++LP+A E+ PEL+++SAG+D+A+GCPEG M+V PAC+ H+ + L+ LA  RV V+LEGGYC++SL +   LTL +L G   PP +E    P   + + + +C+      W+ L +            D  E     LRH     W     P  + P  D      P K   N     ++  LR +   +    K C+ YD +M  H N   + HPE P R Q I +   D  LL + KQL  R A+ DE+ L H+  +V ++  +    P   H     +NS+Y++  ++  A L+ GL+L  +D V    S +G   +RPPGHHAE ++P GFC FNNVAIAA YA+  +   ++++LIVDWDVHHGNGTQH F +N  VLYISLHRY++G FFP   DG+   VG     GFNVNI WNK+ + D EY  AF  ++MPI++EFNP LV+VSAGFDAA GDPLGG  VT E +G +T  L++LA+G++I+ LEGGYN+N IS  M+ C  +LLG   PT Q+    + K       S +E++++ L+ Q+ +W+ L+F
Sbjct:  116 TALIYDESMSQHCCLWDKEHYECPERFTRVLERCRELNLTERCLELPSRSATKDEILRLHTEEHFERLKETSGIRDDERMEELSSRYDSIYIHPSTFELSLLASGSTIELVDHLVAGKAQNGMAIIRPPGHHAMKAEYNGYCFFNNVALATQHALDVHKLQRILIIDYDVHHGQGTQRFFYNDPRVVYFSIHRFEHGSFWPHLHESDYHAIGSGAGTGYNFNVPLNATGMTNGDYLAIFQQLLLPVALEFQPELIIVSAGYDAALGCPEGEMEVTPACYPHLLNPLLRLADARVAVVLEGGYCLDSLAEGAALTLRSLLGDPCPPLVETVPLPRAELAQALLSCIAVHRPHWRCLQLQQTYDCVELQDRDKEEDLHTVLRH-----WIGGPPPMDRYPTRDTAIPLPPEKLTSNAA---RLQVLRAETKLSVPSFKVCYAYDAQMLLHCNLNDTGHPEQPSRIQHIHKMHDDYGLLKQMKQLSPRAATTDEVCLAHTRAHVNTVRRLLGREPKELHDAAGIYNSVYLHPRTFDCATLAAGLVLQAVDSVLRGESRSGICNVRPPGHHAEQDHPHGFCIFNNVAIAAQYAIRDF--GLERVLIVDWDVHHGNGTQHIFESNPKVLYISLHRYEHGSFFPKGPDGNFDVVGKGAGRGFNVNIPWNKKGMGDLEYALAFQQLIMPIAYEFNPQLVLVSAGFDAAIGDPLGGCKVTAEGYGMLTHWLSALASGRIIVCLEGGYNVNSISYAMTMCTKTLLGDPVPTPQLGATALQKPPTVAFQSCVESLQQCLQVQRNHWRSLEF 906          

HSP 2 Score: 283.493 bits (724), Expect = 6.952e-79
Identity = 160/463 (34.56%), Postives = 248/463 (53.56%), Query Frame = 2
Query:  236 ELRINFPN-KTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLE----KFDEP----CDSVKETIQNCLKFLHFFWKSLS-----------VNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKE--------------NDQLNHKIYELRTKNAFNNYPNKTC 1522
            E +++ P+ K  + YD QMLLH N+ D  + E+P R++  ++   +  LL+   ++  +    + +  +H+++HV  +         +L + +  ++ V+    T   + ++AG  ++ + +VL   +++G C +RPPGHHA +    GFCIFNNV IAA+YA  ++  +++LIVDWDVHHGN TQ+ F +  KVLYIS+HRYE G+F+PK  + N+D +G   GRG+N+NIP NK  M + +Y   F  +I+PIAYE+NP+LVL+SAGFD+AIG P G   V    +  +TH L  LA GR++V LEGGY + S+  ++ +   TL G   P  +       +P      S  E++Q CL+     W+SL            V   +N +     LRHL  S  +++        D P+   E              +D L      L     F  YP KTC
Sbjct:  534 ETKLSVPSFKVCYAYDAQMLLHCNLNDTGHPEQPSRIQHIHKMHDDYGLLKQMKQLSPRAATTDEVCLAHTRAHVNTVRRLLGREPKELHDAAGIYNSVYLHPRTFDCATLAAGLVLQAVDSVLRGESRSGICNVRPPGHHAEQDHPHGFCIFNNVAIAAQYAIRDFGLERVLIVDWDVHHGNGTQHIFESNPKVLYISLHRYEHGSFFPKGPDGNFDVVGKGAGRGFNVNIPWNKKGMGDLEYALAFQQLIMPIAYEFNPQLVLVSAGFDAAIGDPLGGCKVTAEGYGMLTHWLSALASGRIIVCLEGGYNVNSISYAMTMCTKTLLGDPVPTPQLGATALQKPPTVAFQSCVESLQQCLQVQRNHWRSLEFVGRRLPRDPVVGENNNEDFLTASLRHLNISNDDATAAAGGLAGDRPDCGDERPSGSKPKVKVKTLSDYLAENKEALEQSEMFAVYPLKTC 996          

HSP 3 Score: 244.973 bits (624), Expect = 3.761e-66
Identity = 130/366 (35.52%), Postives = 220/366 (60.11%), Query Frame = 2
Query: 1517 TCFVYDCRMENH--MNERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIY--HLFEE---EFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQII-NFPINKSGI-EAIRKTLEYQKPYWKCLKFYE 2587
            T  +YD  M  H  + ++  H E P R   + E  R+ +L  RC +L SR A+KDEI  +H+  + E L    +E+  I      EE    ++SIYI+  ++  +LL+ G  + ++D + + +++NG AIIRPPGHHA      G+CFFNNVA+A  +AL  +   +++ILI+D+DVHHG GTQ  F+ +  V+Y S+HR+++G F+P   +    A+G     G+N N+  N   + + +Y++ F  +++P++ EF P+L+IVSAG+DAA G P G + VTP C+ ++   L  LA+ +V + LEGGY L+ +++  +  + SLLG P   ++   P+ ++ + +A+   +   +P+W+CL+  +
Sbjct:  116 TALIYDESMSQHCCLWDKE-HYECPERFTRVLERCRELNLTERCLELPSRSATKDEILRLHTEEHFERL----KETSGIRDDERMEELSSRYDSIYIHPSTFELSLLASGSTIELVDHLVAGKAQNGMAIIRPPGHHAMKAEYNGYCFFNNVALATQHALDVHK--LQRILIIDYDVHHGQGTQRFFYNDPRVVYFSIHRFEHGSFWPHLHESDYHAIGSGAGTGYNFNVPLNATGMTNGDYLAIFQQLLLPVALEFQPELIIVSAGYDAALGCPEGEMEVTPACYPHLLNPLLRLADARVAVVLEGGYCLDSLAEGAALTLRSLLGDPCPPLVETVPLPRAELAQALLSCIAVHRPHWRCLQLQQ 474          

HSP 4 Score: 96.6709 bits (239), Expect = 8.141e-20
Identity = 45/108 (41.67%), Postives = 61/108 (56.48%), Query Frame = 2
Query: 3086 VYAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQVFCGRFVQAHMMQHFQNTRHAIVLSFVDLSSWCYECDSYVHNECLNHAKREAHIAKFGVP 3409
            ++AV PL  C HL  ++   +   +D  A C++C ST ENW+CL+C  V CGR+V AHM QH    +H + +S  DLS WCY C +YV +  L       H  KF  P
Sbjct:  987 MFAVYPLKTCPHLRLLRPEEAPRSLDSGAECSVCGSTGENWVCLSCRHVACGRYVNAHMEQHSVEEQHPLAMSTADLSVWCYACSAYVDHPRLYAYLNPLHEDKFQEP 1094          
BLAST of Histone deacetylase,putative vs. Ensembl Fly
Match: HDAC6 (gene:FBgn0026428 transcript:FBtr0074008)

HSP 1 Score: 660.603 bits (1703), Expect = 0.000e+0
Identity = 336/801 (41.95%), Postives = 488/801 (60.92%), Query Frame = 2
Query:  263 TAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQ-LKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGK-APPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVA---------DNHEPYPEYLRHLPESTWNSSKVP--KLPIEDN-----PNKCKENDQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMN-ERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLG--YPTNQIINFPINK-------SGIEAIRKTLEYQKPYWKCLKF 2581
            TA +YDE M  H  +WD  ++E P+R     E   E NL E C+ + ++    + I   H++ H + +++T  +   + ++ELSS++D ++   +T   S +++GSTIE++  ++  +A+NG  +IRPPGHHAM++E +G+C FNNV +A ++A   +  Q+ILI+D+DVHHG  TQ  FYN  +V+Y SIHR+E G+FWP L ES+Y  IG+  G GYN N+PLN T MTN DYL+IF  ++LP+A E+ PEL+++SAG+D+A+GCPEG M+V PAC+ H+ + L+ LA  RV V+LEGGYC++SL +   LTL +L G   PP +E    P   + + + +C+      W+ L +            D  E     LRH     W     P  + P  D      P K   N     ++  LR +   +    K C+ YD +M  H N   + HPE P R Q I +   D  LL + KQL  R A+ DE+ L H+  +V ++  +    P   H     +NS+Y++  ++  A L+ GL+L  +D V    S +G   +RPPGHHAE ++P GFC FNNVAIAA YA+  +   ++++LIVDWDVHHGNGTQH F +N  VLYISLHRY++G FFP   DG+   VG     GFNVNI WNK+ + D EY  AF  ++MPI++EFNP LV+VSAGFDAA GDPLGG  VT E +G +T  L++LA+G++I+ LEGGYN+N IS  M+ C  +LLG   PT Q+    + K       S +E++++ L+ Q+ +W+ L+F
Sbjct:  106 TALIYDESMSQHCCLWDKEHYECPERFTRVLERCRELNLTERCLELPSRSATKDEILRLHTEEHFERLKETSGIRDDERMEELSSRYDSIYIHPSTFELSLLASGSTIELVDHLVAGKAQNGMAIIRPPGHHAMKAEYNGYCFFNNVALATQHALDVHKLQRILIIDYDVHHGQGTQRFFYNDPRVVYFSIHRFEHGSFWPHLHESDYHAIGSGAGTGYNFNVPLNATGMTNGDYLAIFQQLLLPVALEFQPELIIVSAGYDAALGCPEGEMEVTPACYPHLLNPLLRLADARVAVVLEGGYCLDSLAEGAALTLRSLLGDPCPPLVETVPLPRAELAQALLSCIAVHRPHWRCLQLQQTYDCVELQDRDKEEDLHTVLRH-----WIGGPPPMDRYPTRDTAIPLPPEKLTSNAA---RLQVLRAETKLSVPSFKVCYAYDAQMLLHCNLNDTGHPEQPSRIQHIHKMHDDYGLLKQMKQLSPRAATTDEVCLAHTRAHVNTVRRLLGREPKELHDAAGIYNSVYLHPRTFDCATLAAGLVLQAVDSVLRGESRSGICNVRPPGHHAEQDHPHGFCIFNNVAIAAQYAIRDF--GLERVLIVDWDVHHGNGTQHIFESNPKVLYISLHRYEHGSFFPKGPDGNFDVVGKGAGRGFNVNIPWNKKGMGDLEYALAFQQLIMPIAYEFNPQLVLVSAGFDAAIGDPLGGCKVTAEGYGMLTHWLSALASGRIIVCLEGGYNVNSISYAMTMCTKTLLGDPVPTPQLGATALQKPPTVAFQSCVESLQQCLQVQRNHWRSLEF 896          

HSP 2 Score: 283.878 bits (725), Expect = 5.543e-79
Identity = 160/463 (34.56%), Postives = 248/463 (53.56%), Query Frame = 2
Query:  236 ELRINFPN-KTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLE----KFDEP----CDSVKETIQNCLKFLHFFWKSLS-----------VNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKE--------------NDQLNHKIYELRTKNAFNNYPNKTC 1522
            E +++ P+ K  + YD QMLLH N+ D  + E+P R++  ++   +  LL+   ++  +    + +  +H+++HV  +         +L + +  ++ V+    T   + ++AG  ++ + +VL   +++G C +RPPGHHA +    GFCIFNNV IAA+YA  ++  +++LIVDWDVHHGN TQ+ F +  KVLYIS+HRYE G+F+PK  + N+D +G   GRG+N+NIP NK  M + +Y   F  +I+PIAYE+NP+LVL+SAGFD+AIG P G   V    +  +TH L  LA GR++V LEGGY + S+  ++ +   TL G   P  +       +P      S  E++Q CL+     W+SL            V   +N +     LRHL  S  +++        D P+   E              +D L      L     F  YP KTC
Sbjct:  524 ETKLSVPSFKVCYAYDAQMLLHCNLNDTGHPEQPSRIQHIHKMHDDYGLLKQMKQLSPRAATTDEVCLAHTRAHVNTVRRLLGREPKELHDAAGIYNSVYLHPRTFDCATLAAGLVLQAVDSVLRGESRSGICNVRPPGHHAEQDHPHGFCIFNNVAIAAQYAIRDFGLERVLIVDWDVHHGNGTQHIFESNPKVLYISLHRYEHGSFFPKGPDGNFDVVGKGAGRGFNVNIPWNKKGMGDLEYALAFQQLIMPIAYEFNPQLVLVSAGFDAAIGDPLGGCKVTAEGYGMLTHWLSALASGRIIVCLEGGYNVNSISYAMTMCTKTLLGDPVPTPQLGATALQKPPTVAFQSCVESLQQCLQVQRNHWRSLEFVGRRLPRDPVVGENNNEDFLTASLRHLNISNDDATAAAGGLAGDRPDCGDERPSGSKPKVKVKTLSDYLAENKEALEQSEMFAVYPLKTC 986          

HSP 3 Score: 244.973 bits (624), Expect = 3.644e-66
Identity = 130/366 (35.52%), Postives = 220/366 (60.11%), Query Frame = 2
Query: 1517 TCFVYDCRMENH--MNERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIY--HLFEE---EFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQII-NFPINKSGI-EAIRKTLEYQKPYWKCLKFYE 2587
            T  +YD  M  H  + ++  H E P R   + E  R+ +L  RC +L SR A+KDEI  +H+  + E L    +E+  I      EE    ++SIYI+  ++  +LL+ G  + ++D + + +++NG AIIRPPGHHA      G+CFFNNVA+A  +AL  +   +++ILI+D+DVHHG GTQ  F+ +  V+Y S+HR+++G F+P   +    A+G     G+N N+  N   + + +Y++ F  +++P++ EF P+L+IVSAG+DAA G P G + VTP C+ ++   L  LA+ +V + LEGGY L+ +++  +  + SLLG P   ++   P+ ++ + +A+   +   +P+W+CL+  +
Sbjct:  106 TALIYDESMSQHCCLWDKE-HYECPERFTRVLERCRELNLTERCLELPSRSATKDEILRLHTEEHFERL----KETSGIRDDERMEELSSRYDSIYIHPSTFELSLLASGSTIELVDHLVAGKAQNGMAIIRPPGHHAMKAEYNGYCFFNNVALATQHALDVHK--LQRILIIDYDVHHGQGTQRFFYNDPRVVYFSIHRFEHGSFWPHLHESDYHAIGSGAGTGYNFNVPLNATGMTNGDYLAIFQQLLLPVALEFQPELIIVSAGYDAALGCPEGEMEVTPACYPHLLNPLLRLADARVAVVLEGGYCLDSLAEGAALTLRSLLGDPCPPLVETVPLPRAELAQALLSCIAVHRPHWRCLQLQQ 464          

HSP 4 Score: 96.6709 bits (239), Expect = 8.969e-20
Identity = 45/108 (41.67%), Postives = 61/108 (56.48%), Query Frame = 2
Query: 3086 VYAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQVFCGRFVQAHMMQHFQNTRHAIVLSFVDLSSWCYECDSYVHNECLNHAKREAHIAKFGVP 3409
            ++AV PL  C HL  ++   +   +D  A C++C ST ENW+CL+C  V CGR+V AHM QH    +H + +S  DLS WCY C +YV +  L       H  KF  P
Sbjct:  977 MFAVYPLKTCPHLRLLRPEEAPRSLDSGAECSVCGSTGENWVCLSCRHVACGRYVNAHMEQHSVEEQHPLAMSTADLSVWCYACSAYVDHPRLYAYLNPLHEDKFQEP 1084          
BLAST of Histone deacetylase,putative vs. Ensembl Fly
Match: HDAC6 (gene:FBgn0026428 transcript:FBtr0074010)

HSP 1 Score: 660.218 bits (1702), Expect = 0.000e+0
Identity = 336/801 (41.95%), Postives = 488/801 (60.92%), Query Frame = 2
Query:  263 TAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQ-LKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGK-APPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVA---------DNHEPYPEYLRHLPESTWNSSKVP--KLPIEDN-----PNKCKENDQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMN-ERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLG--YPTNQIINFPINK-------SGIEAIRKTLEYQKPYWKCLKF 2581
            TA +YDE M  H  +WD  ++E P+R     E   E NL E C+ + ++    + I   H++ H + +++T  +   + ++ELSS++D ++   +T   S +++GSTIE++  ++  +A+NG  +IRPPGHHAM++E +G+C FNNV +A ++A   +  Q+ILI+D+DVHHG  TQ  FYN  +V+Y SIHR+E G+FWP L ES+Y  IG+  G GYN N+PLN T MTN DYL+IF  ++LP+A E+ PEL+++SAG+D+A+GCPEG M+V PAC+ H+ + L+ LA  RV V+LEGGYC++SL +   LTL +L G   PP +E    P   + + + +C+      W+ L +            D  E     LRH     W     P  + P  D      P K   N     ++  LR +   +    K C+ YD +M  H N   + HPE P R Q I +   D  LL + KQL  R A+ DE+ L H+  +V ++  +    P   H     +NS+Y++  ++  A L+ GL+L  +D V    S +G   +RPPGHHAE ++P GFC FNNVAIAA YA+  +   ++++LIVDWDVHHGNGTQH F +N  VLYISLHRY++G FFP   DG+   VG     GFNVNI WNK+ + D EY  AF  ++MPI++EFNP LV+VSAGFDAA GDPLGG  VT E +G +T  L++LA+G++I+ LEGGYN+N IS  M+ C  +LLG   PT Q+    + K       S +E++++ L+ Q+ +W+ L+F
Sbjct:  113 TALIYDESMSQHCCLWDKEHYECPERFTRVLERCRELNLTERCLELPSRSATKDEILRLHTEEHFERLKETSGIRDDERMEELSSRYDSIYIHPSTFELSLLASGSTIELVDHLVAGKAQNGMAIIRPPGHHAMKAEYNGYCFFNNVALATQHALDVHKLQRILIIDYDVHHGQGTQRFFYNDPRVVYFSIHRFEHGSFWPHLHESDYHAIGSGAGTGYNFNVPLNATGMTNGDYLAIFQQLLLPVALEFQPELIIVSAGYDAALGCPEGEMEVTPACYPHLLNPLLRLADARVAVVLEGGYCLDSLAEGAALTLRSLLGDPCPPLVETVPLPRAELAQALLSCIAVHRPHWRCLQLQQTYDCVELQDRDKEEDLHTVLRH-----WIGGPPPMDRYPTRDTAIPLPPEKLTSNAA---RLQVLRAETKLSVPSFKVCYAYDAQMLLHCNLNDTGHPEQPSRIQHIHKMHDDYGLLKQMKQLSPRAATTDEVCLAHTRAHVNTVRRLLGREPKELHDAAGIYNSVYLHPRTFDCATLAAGLVLQAVDSVLRGESRSGICNVRPPGHHAEQDHPHGFCIFNNVAIAAQYAIRDF--GLERVLIVDWDVHHGNGTQHIFESNPKVLYISLHRYEHGSFFPKGPDGNFDVVGKGAGRGFNVNIPWNKKGMGDLEYALAFQQLIMPIAYEFNPQLVLVSAGFDAAIGDPLGGCKVTAEGYGMLTHWLSALASGRIIVCLEGGYNVNSISYAMTMCTKTLLGDPVPTPQLGATALQKPPTVAFQSCVESLQQCLQVQRNHWRSLEF 903          

HSP 2 Score: 283.493 bits (724), Expect = 7.015e-79
Identity = 160/463 (34.56%), Postives = 248/463 (53.56%), Query Frame = 2
Query:  236 ELRINFPN-KTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLE----KFDEP----CDSVKETIQNCLKFLHFFWKSLS-----------VNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKE--------------NDQLNHKIYELRTKNAFNNYPNKTC 1522
            E +++ P+ K  + YD QMLLH N+ D  + E+P R++  ++   +  LL+   ++  +    + +  +H+++HV  +         +L + +  ++ V+    T   + ++AG  ++ + +VL   +++G C +RPPGHHA +    GFCIFNNV IAA+YA  ++  +++LIVDWDVHHGN TQ+ F +  KVLYIS+HRYE G+F+PK  + N+D +G   GRG+N+NIP NK  M + +Y   F  +I+PIAYE+NP+LVL+SAGFD+AIG P G   V    +  +TH L  LA GR++V LEGGY + S+  ++ +   TL G   P  +       +P      S  E++Q CL+     W+SL            V   +N +     LRHL  S  +++        D P+   E              +D L      L     F  YP KTC
Sbjct:  531 ETKLSVPSFKVCYAYDAQMLLHCNLNDTGHPEQPSRIQHIHKMHDDYGLLKQMKQLSPRAATTDEVCLAHTRAHVNTVRRLLGREPKELHDAAGIYNSVYLHPRTFDCATLAAGLVLQAVDSVLRGESRSGICNVRPPGHHAEQDHPHGFCIFNNVAIAAQYAIRDFGLERVLIVDWDVHHGNGTQHIFESNPKVLYISLHRYEHGSFFPKGPDGNFDVVGKGAGRGFNVNIPWNKKGMGDLEYALAFQQLIMPIAYEFNPQLVLVSAGFDAAIGDPLGGCKVTAEGYGMLTHWLSALASGRIIVCLEGGYNVNSISYAMTMCTKTLLGDPVPTPQLGATALQKPPTVAFQSCVESLQQCLQVQRNHWRSLEFVGRRLPRDPVVGENNNEDFLTASLRHLNISNDDATAAAGGLAGDRPDCGDERPSGSKPKVKVKTLSDYLAENKEALEQSEMFAVYPLKTC 993          

HSP 3 Score: 244.973 bits (624), Expect = 4.193e-66
Identity = 130/366 (35.52%), Postives = 220/366 (60.11%), Query Frame = 2
Query: 1517 TCFVYDCRMENH--MNERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIY--HLFEE---EFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQII-NFPINKSGI-EAIRKTLEYQKPYWKCLKFYE 2587
            T  +YD  M  H  + ++  H E P R   + E  R+ +L  RC +L SR A+KDEI  +H+  + E L    +E+  I      EE    ++SIYI+  ++  +LL+ G  + ++D + + +++NG AIIRPPGHHA      G+CFFNNVA+A  +AL  +   +++ILI+D+DVHHG GTQ  F+ +  V+Y S+HR+++G F+P   +    A+G     G+N N+  N   + + +Y++ F  +++P++ EF P+L+IVSAG+DAA G P G + VTP C+ ++   L  LA+ +V + LEGGY L+ +++  +  + SLLG P   ++   P+ ++ + +A+   +   +P+W+CL+  +
Sbjct:  113 TALIYDESMSQHCCLWDKE-HYECPERFTRVLERCRELNLTERCLELPSRSATKDEILRLHTEEHFERL----KETSGIRDDERMEELSSRYDSIYIHPSTFELSLLASGSTIELVDHLVAGKAQNGMAIIRPPGHHAMKAEYNGYCFFNNVALATQHALDVHK--LQRILIIDYDVHHGQGTQRFFYNDPRVVYFSIHRFEHGSFWPHLHESDYHAIGSGAGTGYNFNVPLNATGMTNGDYLAIFQQLLLPVALEFQPELIIVSAGYDAALGCPEGEMEVTPACYPHLLNPLLRLADARVAVVLEGGYCLDSLAEGAALTLRSLLGDPCPPLVETVPLPRAELAQALLSCIAVHRPHWRCLQLQQ 471          

HSP 4 Score: 96.6709 bits (239), Expect = 9.312e-20
Identity = 45/108 (41.67%), Postives = 61/108 (56.48%), Query Frame = 2
Query: 3086 VYAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQVFCGRFVQAHMMQHFQNTRHAIVLSFVDLSSWCYECDSYVHNECLNHAKREAHIAKFGVP 3409
            ++AV PL  C HL  ++   +   +D  A C++C ST ENW+CL+C  V CGR+V AHM QH    +H + +S  DLS WCY C +YV +  L       H  KF  P
Sbjct:  984 MFAVYPLKTCPHLRLLRPEEAPRSLDSGAECSVCGSTGENWVCLSCRHVACGRYVNAHMEQHSVEEQHPLAMSTADLSVWCYACSAYVDHPRLYAYLNPLHEDKFQEP 1091          
BLAST of Histone deacetylase,putative vs. Ensembl Zebrafish
Match: hdac6 (histone deacetylase 6 [Source:ZFIN;Acc:ZDB-GENE-030131-3232])

HSP 1 Score: 733.791 bits (1893), Expect = 0.000e+0
Identity = 410/1081 (37.93%), Postives = 586/1081 (54.21%), Query Frame = 2
Query:  263 TAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKENDQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMNE-RSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINF-PINKSGIEAIRKTLEYQKPYWKCLKFYEPLVVTYT----------------EISPNQTNPA-----ALDNIVQIDTNTLAESVRQLGIVEVTFQTEQSIEETLSQPRNDTFITEPN---------SSNPIIHLPPIVSSDNAVEVPATTSINSTTHATQNISANFLSVDQSSGATPVSANVSRVINE--GNSVGLVLQDIMNLSGVSNSDIHHFLGLTSNDPLPERVYAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQVFCGRFVQAHMMQHFQNTRHAIVLSFVDLSSWCYECDSYVHNECLNHAKREAHIAKFG 3403
            T  VY +       +WD  + E P R+    E +    LL  C++++A+ +  + +   H++ +V+L++ TQ MT  +LK L+ ++D V+       ++ +S GS ++++  V+  + +NGF + RPPGHHA   + +GFC+FNN+ IAA+YAQ  +  Q++LIVDWDVHHG   QY F     VLY S+HRYEDG+FWP L+ES+   +G+  G+GYNIN+P NK  M + DY++ F  ++LP+AYE+ P+LVL++AGFD+ IG P+G M V P CF+ +TH L  +A+GR+V+ LEGGY ++S  + V  ++ +L G   P L     PC+S  ++I   +  L+ FWKSL         P  E +  LP       KV   PI                                T  VYD RM  H N   S HPE P+R   IF    +  LLSRC ++ +RLA+++E+ L HS  ++  + +     P   +   +E+NSI+I+  SY  ALL+ G   N    + + +  N  AI+RPPGHHAE +   GFCFFN  A+ A YA +   ES++ +LIVDWDVHHGNGTQH F  + +VLYISLHRY++G FFP S D +   VG     G+NVNI WN   + D EY++AF ++VMPI+ EF P+LV+VSAGFDAARGDPLGG  VTPE + ++T  L SLA G+V++ LEGGYNL  IS+ MS C S LLG     + +  P+  S   +I   L    P+W  L+   P  +  +                + SP Q+ P+     A     Q   + L   +  L +   T          +   R      +PN         S +P+   P    + +  +V A T         ++IS   ++ D S+    V    S V+    GN+V  VL+ +    G   +D+             + +Y V PL WC HL  V+  P A  IDV   C  C    ENW+CL CY+V CGR+V  HM+ H Q + H +VLSF DLS WCY C+SYVHN+ L+ AK  AH+ KFG
Sbjct:   63 TGLVYVDAFTRFHCLWDASHPECPARVSTVMEMLETEGLLGRCVQVEARAVTEDELLLVHTKEYVELMKSTQNMTEEELKTLAEKYDSVYLHPGFFSSACLSVGSVLQLVDKVMTSQLRNGFSINRPPGHHAQADKMNGFCMFNNLAIAARYAQKRHRVQRVLIVDWDVHHGQGIQYIFEEDPSVLYFSVHRYEDGSFWPHLKESDSSSVGSGAGQGYNINLPWNKVGMESGDYITAFQQLLLPVAYEFQPQLVLVAAGFDAVIGDPKGGMQVSPECFSILTHMLKGVAQGRLVLALEGGYNLQSTAEGVCASMRSLLGDPCPHLPSSGAPCESALKSISKTISDLYPFWKSLQTFEGG---PLSE-VSPLPAPVCAEVKVSS-PI--------------------------------TGLVYDQRMMLHHNMWDSHHPELPQRISRIFSRHEELRLLSRCHRIPARLATEEELALCHSSKHISIIKSSEHMKPRDLNRLGDEYNSIFISNESYTCALLAAGSCFNSAQAILTGQVRNAVAIVRPPGHHAEKDTACGFCFFNTAALTARYAQSITRESLR-VLIVDWDVHHGNGTQHIFEEDDSVLYISLHRYEDGAFFPNSEDANYDKVGLGKGRGYNVNIPWNGGKMGDPEYMAAFHHLVMPIAREFAPELVLVSAGFDAARGDPLGGFQVTPEGYAHLTHQLMSLAAGRVLIILEGGYNLTSISESMSMCTSMLLGDSPPSLDHLTPLKTSATVSINNVLRAHAPFWSSLRVNIPESLRLSLPSPKPKGKCTPGGKGKKSPRQSTPSQSPGQATHRPDQSGFDELTADLLSLNLNTSTSSNTSPESVAVGGARRK---VKPNTHRVSAGLESESPLKLNPEKAGAGDDTDVKAET-------PNRSISEPVVTCDSSA----VKDQESLVLEAAGGNTVQSVLERVF---GAQATDV-------------DTMYVVDPLPWCPHLESVRPVP-AGGIDVFQPCEECGGEAENWICLFCYKVLCGRYVNQHMVTHGQESGHPVVLSFADLSVWCYACESYVHNKVLHEAKNAAHLVKFG 1074          

HSP 2 Score: 328.946 bits (842), Expect = 1.151e-94
Identity = 157/379 (41.42%), Postives = 231/379 (60.95%), Query Frame = 2
Query:  236 ELRINFPNKTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQ-LNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHEPYPEYLR 1369
            E++++ P  T  VYD++M+LH NMWD+ + E P R+   +    E  LL  C RI A+    E +   HS  H+ +I+ ++ M    L  L  +++ +F  N +   + ++AGS     +A+L  + +N   ++RPPGHHA +  A GFC FN   + A+YAQ +   + ++LIVDWDVHHGN TQ+ F     VLYIS+HRYEDG F+P   ++NYD +G  +GRGYN+NIP N   M + +Y++ FH +++PIA E+ PELVL+SAGFD+A G P G   V P  +AH+TH+LM LA GRV+++LEGGY + S+ +S+ +  + L G +PP L+       S   +I N L+    FW SL VN+       PE LR
Sbjct:  436 EVKVSSP-ITGLVYDQRMMLHHNMWDSHHPELPQRISRIFSRHEELRLLSRCHRIPARLATEEELALCHSSKHISIIKSSEHMKPRDLNRLGDEYNSIFISNESYTCALLAAGSCFNSAQAILTGQVRNAVAIVRPPGHHAEKDTACGFCFFNTAALTARYAQSITRESLRVLIVDWDVHHGNGTQHIFEEDDSVLYISLHRYEDGAFFPNSEDANYDKVGLGKGRGYNVNIPWNGGKMGDPEYMAAFHHLVMPIAREFAPELVLVSAGFDAARGDPLGGFQVTPEGYAHLTHQLMSLAAGRVLIILEGGYNLTSISESMSMCTSMLLGDSPPSLDHLTPLKTSATVSINNVLRAHAPFWSSLRVNI-------PESLR 806          

HSP 3 Score: 306.605 bits (784), Expect = 5.866e-87
Identity = 157/422 (37.20%), Postives = 254/422 (60.19%), Query Frame = 2
Query: 1367 RHLPESTWNSSKVPKLPIEDNPNKCKENDQLNHKIYELRTKNAFNNYPNKTCFVY-DCRMENHMNERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINFPIN-KSGIEAIRKTLEYQKPYWKCLKFYE--PLVVTYTEISP 2620
            R  PE+  N   + +   +   ++ K  +++++++  L  +    +    T  VY D     H    + HPE P R   + E L    LL RC Q+E+R  ++DE+ L+H+  YVE + +    +        E+++S+Y++   + SA LS G +L ++D+V + +  NGF+I RPPGHHA+ +   GFC FNN+AIAA YA  ++   ++++LIVDWDVHHG G Q+ F  + +VLY S+HRY++G F+P   +   S+VG    +G+N+N+ WNK  +   +YI+AF  +++P+++EF P LV+V+AGFDA  GDP GG+ V+PECF  +T ML  +A G+++LALEGGYNL   ++ +   + SLLG P   + +     +S +++I KT+    P+WK L+ +E  PL    +E+SP
Sbjct:   15 RGTPETKNNKKNLQEARRKGRMDRSKAEEEMSNELQNLDVQG--KSKATGTGLVYVDAFTRFHCLWDASHPECPARVSTVMEMLETEGLLGRCVQVEARAVTEDELLLVHTKEYVELMKSTQNMTEEELKTLAEKYDSVYLHPGFFSSACLSVGSVLQLVDKVMTSQLRNGFSINRPPGHHAQADKMNGFCMFNNLAIAARYAQKRHR--VQRVLIVDWDVHHGQGIQYIFEEDPSVLYFSVHRYEDGSFWPHLKESDSSSVGSGAGQGYNINLPWNKVGMESGDYITAFQQLLLPVAYEFQPQLVLVAAGFDAVIGDPKGGMQVSPECFSILTHMLKGVAQGRLVLALEGGYNLQSTAEGVCASMRSLLGDPCPHLPSSGAPCESALKSISKTISDLYPFWKSLQTFEGGPL----SEVSP 428          
BLAST of Histone deacetylase,putative vs. Ensembl Zebrafish
Match: hdac6 (histone deacetylase 6 [Source:ZFIN;Acc:ZDB-GENE-030131-3232])

HSP 1 Score: 733.791 bits (1893), Expect = 0.000e+0
Identity = 410/1081 (37.93%), Postives = 586/1081 (54.21%), Query Frame = 2
Query:  263 TAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKENDQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMNE-RSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINF-PINKSGIEAIRKTLEYQKPYWKCLKFYEPLVVTYT----------------EISPNQTNPA-----ALDNIVQIDTNTLAESVRQLGIVEVTFQTEQSIEETLSQPRNDTFITEPN---------SSNPIIHLPPIVSSDNAVEVPATTSINSTTHATQNISANFLSVDQSSGATPVSANVSRVINE--GNSVGLVLQDIMNLSGVSNSDIHHFLGLTSNDPLPERVYAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQVFCGRFVQAHMMQHFQNTRHAIVLSFVDLSSWCYECDSYVHNECLNHAKREAHIAKFG 3403
            T  VY +       +WD  + E P R+    E +    LL  C++++A+ +  + +   H++ +V+L++ TQ MT  +LK L+ ++D V+       ++ +S GS ++++  V+  + +NGF + RPPGHHA   + +GFC+FNN+ IAA+YAQ  +  Q++LIVDWDVHHG   QY F     VLY S+HRYEDG+FWP L+ES+   +G+  G+GYNIN+P NK  M + DY++ F  ++LP+AYE+ P+LVL++AGFD+ IG P+G M V P CF+ +TH L  +A+GR+V+ LEGGY ++S  + V  ++ +L G   P L     PC+S  ++I   +  L+ FWKSL         P  E +  LP       KV   PI                                T  VYD RM  H N   S HPE P+R   IF    +  LLSRC ++ +RLA+++E+ L HS  ++  + +     P   +   +E+NSI+I+  SY  ALL+ G   N    + + +  N  AI+RPPGHHAE +   GFCFFN  A+ A YA +   ES++ +LIVDWDVHHGNGTQH F  + +VLYISLHRY++G FFP S D +   VG     G+NVNI WN   + D EY++AF ++VMPI+ EF P+LV+VSAGFDAARGDPLGG  VTPE + ++T  L SLA G+V++ LEGGYNL  IS+ MS C S LLG     + +  P+  S   +I   L    P+W  L+   P  +  +                + SP Q+ P+     A     Q   + L   +  L +   T          +   R      +PN         S +P+   P    + +  +V A T         ++IS   ++ D S+    V    S V+    GN+V  VL+ +    G   +D+             + +Y V PL WC HL  V+  P A  IDV   C  C    ENW+CL CY+V CGR+V  HM+ H Q + H +VLSF DLS WCY C+SYVHN+ L+ AK  AH+ KFG
Sbjct:   63 TGLVYVDAFTRFHCLWDASHPECPARVSTVMEMLETEGLLGRCVQVEARAVTEDELLLVHTKEYVELMKSTQNMTEEELKTLAEKYDSVYLHPGFFSSACLSVGSVLQLVDKVMTSQLRNGFSINRPPGHHAQADKMNGFCMFNNLAIAARYAQKRHRVQRVLIVDWDVHHGQGIQYIFEEDPSVLYFSVHRYEDGSFWPHLKESDSSSVGSGAGQGYNINLPWNKVGMESGDYITAFQQLLLPVAYEFQPQLVLVAAGFDAVIGDPKGGMQVSPECFSILTHMLKGVAQGRLVLALEGGYNLQSTAEGVCASMRSLLGDPCPHLPSSGAPCESALKSISKTISDLYPFWKSLQTFEGG---PLSE-VSPLPAPVCAEVKVSS-PI--------------------------------TGLVYDQRMMLHHNMWDSHHPELPQRISRIFSRHEELRLLSRCHRIPARLATEEELALCHSSKHISIIKSSEHMKPRDLNRLGDEYNSIFISNESYTCALLAAGSCFNSAQAILTGQVRNAVAIVRPPGHHAEKDTACGFCFFNTAALTARYAQSITRESLR-VLIVDWDVHHGNGTQHIFEEDDSVLYISLHRYEDGAFFPNSEDANYDKVGLGKGRGYNVNIPWNGGKMGDPEYMAAFHHLVMPIAREFAPELVLVSAGFDAARGDPLGGFQVTPEGYAHLTHQLMSLAAGRVLIILEGGYNLTSISESMSMCTSMLLGDSPPSLDHLTPLKTSATVSINNVLRAHAPFWSSLRVNIPESLRLSLPSPKPKGKCTPGGKGKKSPRQSTPSQSPGQATHRPDQSGFDELTADLLSLNLNTSTSSNTSPESVAVGGARRK---VKPNTHRVSAGLESESPLKLNPEKAGAGDDTDVKAET-------PNRSISEPVVTCDSSA----VKDQESLVLEAAGGNTVQSVLERVF---GAQATDV-------------DTMYVVDPLPWCPHLESVRPVP-AGGIDVFQPCEECGGEAENWICLFCYKVLCGRYVNQHMVTHGQESGHPVVLSFADLSVWCYACESYVHNKVLHEAKNAAHLVKFG 1074          

HSP 2 Score: 328.946 bits (842), Expect = 1.151e-94
Identity = 157/379 (41.42%), Postives = 231/379 (60.95%), Query Frame = 2
Query:  236 ELRINFPNKTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQ-LNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHEPYPEYLR 1369
            E++++ P  T  VYD++M+LH NMWD+ + E P R+   +    E  LL  C RI A+    E +   HS  H+ +I+ ++ M    L  L  +++ +F  N +   + ++AGS     +A+L  + +N   ++RPPGHHA +  A GFC FN   + A+YAQ +   + ++LIVDWDVHHGN TQ+ F     VLYIS+HRYEDG F+P   ++NYD +G  +GRGYN+NIP N   M + +Y++ FH +++PIA E+ PELVL+SAGFD+A G P G   V P  +AH+TH+LM LA GRV+++LEGGY + S+ +S+ +  + L G +PP L+       S   +I N L+    FW SL VN+       PE LR
Sbjct:  436 EVKVSSP-ITGLVYDQRMMLHHNMWDSHHPELPQRISRIFSRHEELRLLSRCHRIPARLATEEELALCHSSKHISIIKSSEHMKPRDLNRLGDEYNSIFISNESYTCALLAAGSCFNSAQAILTGQVRNAVAIVRPPGHHAEKDTACGFCFFNTAALTARYAQSITRESLRVLIVDWDVHHGNGTQHIFEEDDSVLYISLHRYEDGAFFPNSEDANYDKVGLGKGRGYNVNIPWNGGKMGDPEYMAAFHHLVMPIAREFAPELVLVSAGFDAARGDPLGGFQVTPEGYAHLTHQLMSLAAGRVLIILEGGYNLTSISESMSMCTSMLLGDSPPSLDHLTPLKTSATVSINNVLRAHAPFWSSLRVNI-------PESLR 806          

HSP 3 Score: 306.605 bits (784), Expect = 5.866e-87
Identity = 157/422 (37.20%), Postives = 254/422 (60.19%), Query Frame = 2
Query: 1367 RHLPESTWNSSKVPKLPIEDNPNKCKENDQLNHKIYELRTKNAFNNYPNKTCFVY-DCRMENHMNERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINFPIN-KSGIEAIRKTLEYQKPYWKCLKFYE--PLVVTYTEISP 2620
            R  PE+  N   + +   +   ++ K  +++++++  L  +    +    T  VY D     H    + HPE P R   + E L    LL RC Q+E+R  ++DE+ L+H+  YVE + +    +        E+++S+Y++   + SA LS G +L ++D+V + +  NGF+I RPPGHHA+ +   GFC FNN+AIAA YA  ++   ++++LIVDWDVHHG G Q+ F  + +VLY S+HRY++G F+P   +   S+VG    +G+N+N+ WNK  +   +YI+AF  +++P+++EF P LV+V+AGFDA  GDP GG+ V+PECF  +T ML  +A G+++LALEGGYNL   ++ +   + SLLG P   + +     +S +++I KT+    P+WK L+ +E  PL    +E+SP
Sbjct:   15 RGTPETKNNKKNLQEARRKGRMDRSKAEEEMSNELQNLDVQG--KSKATGTGLVYVDAFTRFHCLWDASHPECPARVSTVMEMLETEGLLGRCVQVEARAVTEDELLLVHTKEYVELMKSTQNMTEEELKTLAEKYDSVYLHPGFFSSACLSVGSVLQLVDKVMTSQLRNGFSINRPPGHHAQADKMNGFCMFNNLAIAARYAQKRHR--VQRVLIVDWDVHHGQGIQYIFEEDPSVLYFSVHRYEDGSFWPHLKESDSSSVGSGAGQGYNINLPWNKVGMESGDYITAFQQLLLPVAYEFQPQLVLVAAGFDAVIGDPKGGMQVSPECFSILTHMLKGVAQGRLVLALEGGYNLQSTAEGVCASMRSLLGDPCPHLPSSGAPCESALKSISKTISDLYPFWKSLQTFEGGPL----SEVSP 428          
BLAST of Histone deacetylase,putative vs. Ensembl Zebrafish
Match: hdac10 (histone deacetylase 10 [Source:NCBI gene;Acc:327253])

HSP 1 Score: 330.872 bits (847), Expect = 5.148e-99
Identity = 164/393 (41.73%), Postives = 235/393 (59.80%), Query Frame = 2
Query:  263 TAFVYDEQMLLHSNMWDN--LYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPN 1435
            +A ++DE+M  +  +W +     E P+RL V YE +    L + C  +  ++   + I  +HS+ +++ ++ T  M   +L   S +++ V+F  N    + ++AG+T++++ +V+    +NG  L+RPPGHH+  S A+GFC+FNNV IAA YA+ NY+  +ILIVDWDVHHG   QY F     VLY S HRYE  +FWP L ES+Y  +G  +G G+NIN+P NK  MTNSDYL+ F  ++LP+AYE++PELV++SAGFDSAIG PEG M   P  FAH+TH LM LA G++ V+LEGGY + SL  SV  T+ +L G   P++      CDS  E+IQN       +W S                +HL +S  N    PK P  D  N
Sbjct:    5 SALIFDEEMSRYKLLWTDPACEIEVPERLTVSYEALRTHGLAQRCKAVPVRQATEQEILLAHSEEYLEAVKQTPGMNVEELMAFSKKYNDVYFHQNIYHCAKLAAGATLQLVDSVMKREVRNGMALVRPPGHHSQRSAANGFCVFNNVAIAALYAKKNYNLNRILIVDWDVHHGQGIQYCFEEDPSVLYFSWHRYEHQSFWPNLPESDYSSVGKGKGSGFNINLPWNKVGMTNSDYLAAFFHVLLPVAYEFDPELVIVSAGFDSAIGDPEGEMCALPEIFAHLTHLLMPLAAGKMCVVLEGGYNLTSLGQSVCQTVHSLLGDPTPRISGLGTACDSALESIQNVRNVQSSYWSS---------------FKHLAQSETN----PKRPRLDATN 378          

HSP 2 Score: 276.559 bits (706), Expect = 2.071e-79
Identity = 139/335 (41.49%), Postives = 203/335 (60.60%), Query Frame = 2
Query: 1577 ESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINFPIN-KSGIEAIRKTLEYQKPYWKCLK 2578
            E P R  + +E LR + L  RCK +  R A++ EI L HS  Y+E++      +      F +++N +Y +Q+ Y  A L+ G  L ++D V      NG A++RPPGHH++ +   GFC FNNVAIAA YA   Y+  + +ILIVDWDVHHG G Q+ F  + +VLY S HRY++  F+P   +   S+VG     GFN+N+ WNK  + +S+Y++AF ++++P+++EF+P+LVIVSAGFD+A GDP G +   PE F ++T +L  LA GK+ + LEGGYNL  +   +   V SLLG PT +I        S +E+I+     Q  YW   K
Sbjct:   28 EVPERLTVSYEALRTHGLAQRCKAVPVRQATEQEILLAHSEEYLEAVKQTPGMNVEELMAFSKKYNDVYFHQNIYHCAKLAAGATLQLVDSVMKREVRNGMALVRPPGHHSQRSAANGFCVFNNVAIAALYAKKNYN--LNRILIVDWDVHHGQGIQYCFEEDPSVLYFSWHRYEHQSFWPNLPESDYSSVGKGKGSGFNINLPWNKVGMTNSDYLAAFFHVLLPVAYEFDPELVIVSAGFDSAIGDPEGEMCALPEIFAHLTHLLMPLAAGKMCVVLEGGYNLTSLGQSVCQTVHSLLGDPTPRISGLGTACDSALESIQNVRNVQSSYWSSFK 360          
BLAST of Histone deacetylase,putative vs. Ensembl Zebrafish
Match: hdac4 (histone deacetylase 4 [Source:ZFIN;Acc:ZDB-GENE-061013-95])

HSP 1 Score: 301.212 bits (770), Expect = 2.207e-85
Identity = 161/378 (42.59%), Postives = 238/378 (62.96%), Query Frame = 2
Query: 1517 TCFVYDCRMENHM---NERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGN--ICQE-----SPTIYHL----FEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWN---KRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARG--DPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLG-----YPTNQIINFPINKSGIEAIRKTLEYQKPYWKCLK 2578
            T  VYD  M+ H       +IHPE   R Q I+  L++  L  +C+ +  R A+ +E+  +HS  +V   G   + Q+     +P    L       + ++I+   HS  +A L+ G +++++ +V S    NGFA++RPPGHHAE + P+GFC+FN+VAIAA   L +   ++ KILIVDWDVHHGNGTQ  F+++ NVLY+SLHRYD+G FFPGS  G+P  VG     GFNVN+A+    + P+ D++Y++AF ++VMPI++EF+PD+V+VS+GFDA  G   PLGG  +T +CFG +T+ L  LA G+++LALEGG++L  I D    CVS+LLG      P + +   P N + I+++ K LE Q  YW+ L+
Sbjct:  599 TGLVYDTLMQKHQCMCGNSNIHPEHAGRIQSIWSRLQETGLRGQCECIRGRKATLEELQTVHSEAHVLLYGTNPLRQKLDSSVTPMFVRLPCGGIGVDSDTIWNEVHSSSAARLAVGSVVDLVFKVASGELRNGFAVVRPPGHHAEESTPMGFCYFNSVAIAAK--LLQQRLNVSKILIVDWDVHHGNGTQQAFYSDPNVLYLSLHRYDDGNFFPGS--GAPDEVGIGPGVGFNVNMAFTGGLEPPMGDADYLAAFRSVVMPIANEFSPDVVLVSSGFDAVEGHPPPLGGYKLTAKCFGYLTKQLMGLAGGRLVLALEGGHDLTAICDASEACVSALLGNELDPIPEDILQQRP-NANAIQSMEKVLEVQSKYWRSLQ 971          

HSP 2 Score: 233.802 bits (595), Expect = 1.213e-62
Identity = 131/382 (34.29%), Postives = 214/382 (56.02%), Query Frame = 2
Query:  263 TAFVYDEQMLLHSNMW--DNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHV---------QLIEDTQTMTAIQLK--ELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLN---KTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPE--GSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDE------PCDSVKETIQNCLKFLHFFWKSLSVNVA 1336
            T  VYD  M  H  M    N++ E   R++  +  + ET L   C  I+ ++   E +   HS++HV         Q ++ + T   ++L    +    D ++ + ++  A+ ++ GS ++++  V     +NGF ++RPPGHHA ES   GFC FN+V IAAK  Q   +  KILIVDWDVHHGN TQ  FY+   VLY+S+HRY+DGNF+P       D +G   G G+N+N+      +  M ++DYL+ F S+++PIA E++P++VL+S+GFD+  G P   G   +   CF ++T +LM LA GR+V+ LEGG+ + ++ D+    ++ L G    +L+   E      P  +  ++++  L+    +W+SL  +V+
Sbjct:  599 TGLVYDTLMQKHQCMCGNSNIHPEHAGRIQSIWSRLQETGLRGQCECIRGRKATLEELQTVHSEAHVLLYGTNPLRQKLDSSVTPMFVRLPCGGIGVDSDTIWNEVHSSSAARLAVGSVVDLVFKVASGELRNGFAVVRPPGHHAEESTPMGFCYFNSVAIAAKLLQQRLNVSKILIVDWDVHHGNGTQQAFYSDPNVLYLSLHRYDDGNFFPG--SGAPDEVGIGPGVGFNVNMAFTGGLEPPMGDADYLAAFRSVVMPIANEFSPDVVLVSSGFDAVEGHPPPLGGYKLTAKCFGYLTKQLMGLAGGRLVLALEGGHDLTAICDASEACVSALLGN---ELDPIPEDILQQRPNANAIQSMEKVLEVQSKYWRSLQRSVS 975          
BLAST of Histone deacetylase,putative vs. Ensembl Zebrafish
Match: hdac4 (histone deacetylase 4 [Source:ZFIN;Acc:ZDB-GENE-061013-95])

HSP 1 Score: 300.827 bits (769), Expect = 4.552e-85
Identity = 161/378 (42.59%), Postives = 238/378 (62.96%), Query Frame = 2
Query: 1517 TCFVYDCRMENHM---NERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGN--ICQE-----SPTIYHL----FEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWN---KRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARG--DPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLG-----YPTNQIINFPINKSGIEAIRKTLEYQKPYWKCLK 2578
            T  VYD  M+ H       +IHPE   R Q I+  L++  L  +C+ +  R A+ +E+  +HS  +V   G   + Q+     +P    L       + ++I+   HS  +A L+ G +++++ +V S    NGFA++RPPGHHAE + P+GFC+FN+VAIAA   L +   ++ KILIVDWDVHHGNGTQ  F+++ NVLY+SLHRYD+G FFPGS  G+P  VG     GFNVN+A+    + P+ D++Y++AF ++VMPI++EF+PD+V+VS+GFDA  G   PLGG  +T +CFG +T+ L  LA G+++LALEGG++L  I D    CVS+LLG      P + +   P N + I+++ K LE Q  YW+ L+
Sbjct:  628 TGLVYDTLMQKHQCMCGNSNIHPEHAGRIQSIWSRLQETGLRGQCECIRGRKATLEELQTVHSEAHVLLYGTNPLRQKLDSSVTPMFVRLPCGGIGVDSDTIWNEVHSSSAARLAVGSVVDLVFKVASGELRNGFAVVRPPGHHAEESTPMGFCYFNSVAIAAK--LLQQRLNVSKILIVDWDVHHGNGTQQAFYSDPNVLYLSLHRYDDGNFFPGS--GAPDEVGIGPGVGFNVNMAFTGGLEPPMGDADYLAAFRSVVMPIANEFSPDVVLVSSGFDAVEGHPPPLGGYKLTAKCFGYLTKQLMGLAGGRLVLALEGGHDLTAICDASEACVSALLGNELDPIPEDILQQRP-NANAIQSMEKVLEVQSKYWRSLQ 1000          

HSP 2 Score: 233.802 bits (595), Expect = 1.233e-62
Identity = 131/382 (34.29%), Postives = 214/382 (56.02%), Query Frame = 2
Query:  263 TAFVYDEQMLLHSNMW--DNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHV---------QLIEDTQTMTAIQLK--ELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLN---KTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPE--GSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDE------PCDSVKETIQNCLKFLHFFWKSLSVNVA 1336
            T  VYD  M  H  M    N++ E   R++  +  + ET L   C  I+ ++   E +   HS++HV         Q ++ + T   ++L    +    D ++ + ++  A+ ++ GS ++++  V     +NGF ++RPPGHHA ES   GFC FN+V IAAK  Q   +  KILIVDWDVHHGN TQ  FY+   VLY+S+HRY+DGNF+P       D +G   G G+N+N+      +  M ++DYL+ F S+++PIA E++P++VL+S+GFD+  G P   G   +   CF ++T +LM LA GR+V+ LEGG+ + ++ D+    ++ L G    +L+   E      P  +  ++++  L+    +W+SL  +V+
Sbjct:  628 TGLVYDTLMQKHQCMCGNSNIHPEHAGRIQSIWSRLQETGLRGQCECIRGRKATLEELQTVHSEAHVLLYGTNPLRQKLDSSVTPMFVRLPCGGIGVDSDTIWNEVHSSSAARLAVGSVVDLVFKVASGELRNGFAVVRPPGHHAEESTPMGFCYFNSVAIAAKLLQQRLNVSKILIVDWDVHHGNGTQQAFYSDPNVLYLSLHRYDDGNFFPG--SGAPDEVGIGPGVGFNVNMAFTGGLEPPMGDADYLAAFRSVVMPIANEFSPDVVLVSSGFDAVEGHPPPLGGYKLTAKCFGYLTKQLMGLAGGRLVLALEGGHDLTAICDASEACVSALLGN---ELDPIPEDILQQRPNANAIQSMEKVLEVQSKYWRSLQRSVS 1004          
BLAST of Histone deacetylase,putative vs. Ensembl Xenopus
Match: gpr107 (G protein-coupled receptor 107 [Source:Xenbase;Acc:XB-GENE-953756])

HSP 1 Score: 602.823 bits (1553), Expect = 0.000e+0
Identity = 315/755 (41.72%), Postives = 431/755 (57.09%), Query Frame = 2
Query:  326 ERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKENDQLNHKIYELRTKNAFNNYP-NKTCFVYDCRMENHMNE-RSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINF-PINKSGIEAIRKTLEYQKPYWKCLKF 2581
            E P R+    + + E  L E C+ +Q          +S S  +V L+  TQ M   +L+ LS ++D V+    +   + ++ GS ++++  VL    +NG  ++RPPGHHA   + +G+C+FN + IAA+YAQ  Y  +++LIVDWDVHHG  TQ+ F N   VLY S+HRYE+G FWP LRES    +G   G  +N+N+  NKT M+++DY+ +F +I+LPIAYE+ P LVL++AGFDS +G P+G M   P CF+H+TH LM LA+GR+++ LEGGY   SL + V   L  L G   PKL     PC   + +  NC+                              +  + S +   P+E              K+ E          P  +T  VYD +M  H N   S HPESP+R   IF+  +D  LL RC ++ SRLA++ E+ + HS +Y++ +       P   H    E+NSIYIN  SY SA L+ G   +V        ++NG  I+RPPGHHAE     GFCFFN VA+AA YA         +I+I+DWDVHHGNGTQH F  + +VLY+SLHRYD GLFFP S D S   VG     GFNVNI WN   + D EY+ AF  +VMPI++EFNP LV++SAGFDAARGDPLGG  V+PE + +MT +L  LA G+VIL LEGGYNL  IS+ M  C  SLLG P   + +  P   S   ++RK  +  + YW+ L+ 
Sbjct:   45 ECPARIWAVRDKMAEYGLAERCVAVQVSP--RGWAGFSPSSRYVALMGSTQNMNVEELQALSDRYDSVYLHPTSFTCASLAVGSVLQLVDKVLRREIRNGLAVVRPPGHHAHVDQMNGYCMFNQLAIAARYAQRTYGAKRVLIVDWDVHHGQGTQFLFENDPSVLYFSVHRYENGGFWPHLRESASSAVGKERGERFNVNVAWNKTRMSDADYIHVFLNILLPIAYEFQPHLVLVAAGFDSVVGDPKGEMSATPGCFSHLTHLLMSLAQGRLILSLEGGYNQRSLAEGVCACLKALLGDPCPKLPLPSAPC---QRSALNCVT----------------------------AARASMSFLNGPPLE--------------KVLEQSMMEVMREVPAQRTALVYDEQMMEHHNMWDSCHPESPQRINQIFKRHKDLGLLDRCSRIPSRLATQKELQMCHSLSYIQKIEASAHMKPRDLHRLGNEYNSIYINSRSYHSARLAAGSTFSV--------AQNGVCIVRPPGHHAEPAEACGFCFFNTVALAARYA------QRLRIMILDWDVHHGNGTQHIFQEDASVLYVSLHRYDEGLFFPNSEDASHDKVGIGKGAGFNVNIPWNGSKMGDPEYLMAFHRVVMPIAYEFNPQLVLISAGFDAARGDPLGGCQVSPEGYAHMTHLLMGLAGGRVILVLEGGYNLTSISESMVMCTHSLLGDPPPTLSDLRPPKPSAFNSVRKVRQAHRKYWRSLRL 738          

HSP 2 Score: 314.309 bits (804), Expect = 1.557e-90
Identity = 149/358 (41.62%), Postives = 228/358 (63.69%), Query Frame = 2
Query:  257 NKTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVN 1330
             +TA VYDEQM+ H NMWD+ + E P R+   ++   +  LL+ C RI ++    + +   HS S++Q IE +  M    L  L ++++ ++ ++ +  ++ ++AGST  V        A+NG C++RPPGHHA  +EA GFC FN V +AA+YAQ      +I+I+DWDVHHGN TQ+ F   + VLY+S+HRY++G F+P   ++++D +G  +G G+N+NIP N + M + +YL  FH +++PIAYE+NP+LVLISAGFD+A G P G   V P  +AHMTH LM LA GRV+++LEGGY + S+ +S+V+   +L G  PP L     P  S   +++   +    +W+SL +N
Sbjct:  394 QRTALVYDEQMMEHHNMWDSCHPESPQRINQIFKRHKDLGLLDRCSRIPSRLATQKELQMCHSLSYIQKIEASAHMKPRDLHRLGNEYNSIYINSRSYHSARLAAGSTFSV--------AQNGVCIVRPPGHHAEPAEACGFCFFNTVALAARYAQ----RLRIMILDWDVHHGNGTQHIFQEDASVLYVSLHRYDEGLFFPNSEDASHDKVGIGKGAGFNVNIPWNGSKMGDPEYLMAFHRVVMPIAYEFNPQLVLISAGFDAARGDPLGGCQVSPEGYAHMTHLLMGLAGGRVILVLEGGYNLTSISESMVMCTHSLLGDPPPTLSDLRPPKPSAFNSVRKVRQAHRKYWRSLRLN 739          

HSP 3 Score: 264.233 bits (674), Expect = 4.676e-73
Identity = 131/331 (39.58%), Postives = 204/331 (61.63%), Query Frame = 2
Query: 1574 PESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQ--IINFPINKSG---IEAIRKTLEY 2551
            PE P R   + + + +  L  RC  ++  ++ +   G   S  YV  +G+    +        + ++S+Y++  S+  A L+ G +L ++D+V      NG A++RPPGHHA V+   G+C FN +AIAA YA   Y    K++LIVDWDVHHG GTQ  F  + +VLY S+HRY+NG F+P   + + SAVG +  E FNVN+AWNK  + D++YI  F+NI++PI++EF P LV+V+AGFD+  GDP G ++ TP CF ++T +L SLA G++IL+LEGGYN   +++ +  C+ +LLG P  +  + + P  +S    + A R ++ +
Sbjct:   44 PECPARIWAVRDKMAEYGLAERCVAVQ--VSPRGWAGFSPSSRYVALMGSTQNMNVEELQALSDRYDSVYLHPTSFTCASLAVGSVLQLVDKVLRREIRNGLAVVRPPGHHAHVDQMNGYCMFNQLAIAARYAQRTYGA--KRVLIVDWDVHHGQGTQFLFENDPSVLYFSVHRYENGGFWPHLRESASSAVGKERGERFNVNVAWNKTRMSDADYIHVFLNILLPIAYEFQPHLVLVAAGFDSVVGDPKGEMSATPGCFSHLTHLLMSLAQGRLILSLEGGYNQRSLAEGVCACLKALLGDPCPKLPLPSAPCQRSALNCVTAARASMSF 370          

HSP 4 Score: 109.768 bits (273), Expect = 1.224e-23
Identity = 49/90 (54.44%), Postives = 59/90 (65.56%), Query Frame = 2
Query: 3089 YAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQVFCGRFVQAHMMQHFQNTRHAIVLSFVDLSSWCYECDSYVHNE 3358
            +AV PL WC HL  V   P A  +DV   C  C S  ENW+CLTCYQV CGR+V  HM+ H   + H +VLSF DLS WCY C+SYVH++
Sbjct:  823 FAVTPLPWCPHLGSVSAVPPAG-LDVRQLCAQCASELENWVCLTCYQVLCGRYVSQHMLCHGLASGHHLVLSFSDLSVWCYGCESYVHHQ 911          
BLAST of Histone deacetylase,putative vs. Ensembl Xenopus
Match: ENSXETT00000022901.1 (histone deacetylase 10 [Source:NCBI gene;Acc:100497245])

HSP 1 Score: 353.984 bits (907), Expect = 3.475e-107
Identity = 164/365 (44.93%), Postives = 240/365 (65.75%), Query Frame = 2
Query:  263 TAFVYDEQMLLHSNMWDN--LYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHEP 1351
            TA VYDE+M+ +  +WD+     E P+RL   Y+ + + +L++ C ++  +E  +E I   HS  ++++++ TQTM   +L+E+S ++  VFF  N+   + +S G T++++ AVL    +NG  L+RPPGHH+   + +GFC+FNNV IAA+YA+  Y  ++ILIVDWDVHHG   QY F     VLY S HRYE   FWP L ES+Y+ +G  +G G+NIN+P NK  M+N+DY+++F  ++LP+A+E+NPELVL+SAG+DSAIG PEG M   P CF+H+T  LM+LA G++  +LEGGY + SL +SV +T+ TL G   PKL     PC S  E+IQN       +WK L  N+   H+P
Sbjct:    5 TALVYDEEMMSYKLLWDDQECSIEVPERLSSSYKRLQDYDLVKRCTQLPVREATDEEITLVHSSDYLEVVKSTQTMNEKELEEISRKYTAVFFHQNSFRCAKLSLGGTLQLVDAVLSGEVQNGMALVRPPGHHSQRDQGNGFCVFNNVAIAAEYAKKKYKLERILIVDWDVHHGQGIQYIFEEDPSVLYFSWHRYEHKTFWPYLSESDYNAVGRGKGTGFNINLPWNKVGMSNADYIAVFFHVLLPLAFEFNPELVLVSAGYDSAIGDPEGRMCATPECFSHLTSMLMNLADGKLCAVLEGGYNLRSLAESVCMTVRTLLGDPLPKLTGEMTPCHSALESIQNVRAAHSPYWKCLLCNLRSAHDP 369          

HSP 2 Score: 288.886 bits (738), Expect = 1.225e-83
Identity = 144/357 (40.34%), Postives = 222/357 (62.18%), Query Frame = 2
Query: 1517 TCFVYDCRMENH---MNERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIIN-FPINKSGIEAIRKTLEYQKPYWKCL 2575
            T  VYD  M ++    +++    E P R    ++ L+D  L+ RC QL  R A+ +EI L+HS +Y+E + +    +         ++ +++ +Q+S+  A LS G  L ++D V S   +NG A++RPPGHH++ +   GFC FNNVAIAA YA  KY   +++ILIVDWDVHHG G Q+ F  + +VLY S HRY++  F+P  ++   +AVG     GFN+N+ WNK  + +++YI+ F ++++P++ EFNP+LV+VSAG+D+A GDP G +  TPECF ++T ML +LA+GK+   LEGGYNL  +++ +   V +LLG P  ++        S +E+I+       PYWKCL
Sbjct:    5 TALVYDEEMMSYKLLWDDQECSIEVPERLSSSYKRLQDYDLVKRCTQLPVREATDEEITLVHSSDYLEVVKSTQTMNEKELEEISRKYTAVFFHQNSFRCAKLSLGGTLQLVDAVLSGEVQNGMALVRPPGHHSQRDQGNGFCVFNNVAIAAEYAKKKYK--LERILIVDWDVHHGQGIQYIFEEDPSVLYFSWHRYEHKTFWPYLSESDYNAVGRGKGTGFNINLPWNKVGMSNADYIAVFFHVLLPLAFEFNPELVLVSAGYDSAIGDPEGRMCATPECFSHLTSMLMNLADGKLCAVLEGGYNLRSLAESVCMTVRTLLGDPLPKLTGEMTPCHSALESIQNVRAAHSPYWKCL 359          
BLAST of Histone deacetylase,putative vs. Ensembl Xenopus
Match: ENSXETT00000022890.1 (histone deacetylase 10 [Source:NCBI gene;Acc:100497245])

HSP 1 Score: 353.984 bits (907), Expect = 7.979e-107
Identity = 164/365 (44.93%), Postives = 240/365 (65.75%), Query Frame = 2
Query:  263 TAFVYDEQMLLHSNMWDN--LYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHEP 1351
            TA VYDE+M+ +  +WD+     E P+RL   Y+ + + +L++ C ++  +E  +E I   HS  ++++++ TQTM   +L+E+S ++  VFF  N+   + +S G T++++ AVL    +NG  L+RPPGHH+   + +GFC+FNNV IAA+YA+  Y  ++ILIVDWDVHHG   QY F     VLY S HRYE   FWP L ES+Y+ +G  +G G+NIN+P NK  M+N+DY+++F  ++LP+A+E+NPELVL+SAG+DSAIG PEG M   P CF+H+T  LM+LA G++  +LEGGY + SL +SV +T+ TL G   PKL     PC S  E+IQN       +WK L  N+   H+P
Sbjct:    5 TALVYDEEMMSYKLLWDDQECSIEVPERLSSSYKRLQDYDLVKRCTQLPVREATDEEITLVHSSDYLEVVKSTQTMNEKELEEISRKYTAVFFHQNSFRCAKLSLGGTLQLVDAVLSGEVQNGMALVRPPGHHSQRDQGNGFCVFNNVAIAAEYAKKKYKLERILIVDWDVHHGQGIQYIFEEDPSVLYFSWHRYEHKTFWPYLSESDYNAVGRGKGTGFNINLPWNKVGMSNADYIAVFFHVLLPLAFEFNPELVLVSAGYDSAIGDPEGRMCATPECFSHLTSMLMNLADGKLCAVLEGGYNLRSLAESVCMTVRTLLGDPLPKLTGEMTPCHSALESIQNVRAAHSPYWKCLLCNLRSAHDP 369          

HSP 2 Score: 289.271 bits (739), Expect = 2.115e-83
Identity = 144/357 (40.34%), Postives = 222/357 (62.18%), Query Frame = 2
Query: 1517 TCFVYDCRMENH---MNERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIIN-FPINKSGIEAIRKTLEYQKPYWKCL 2575
            T  VYD  M ++    +++    E P R    ++ L+D  L+ RC QL  R A+ +EI L+HS +Y+E + +    +         ++ +++ +Q+S+  A LS G  L ++D V S   +NG A++RPPGHH++ +   GFC FNNVAIAA YA  KY   +++ILIVDWDVHHG G Q+ F  + +VLY S HRY++  F+P  ++   +AVG     GFN+N+ WNK  + +++YI+ F ++++P++ EFNP+LV+VSAG+D+A GDP G +  TPECF ++T ML +LA+GK+   LEGGYNL  +++ +   V +LLG P  ++        S +E+I+       PYWKCL
Sbjct:    5 TALVYDEEMMSYKLLWDDQECSIEVPERLSSSYKRLQDYDLVKRCTQLPVREATDEEITLVHSSDYLEVVKSTQTMNEKELEEISRKYTAVFFHQNSFRCAKLSLGGTLQLVDAVLSGEVQNGMALVRPPGHHSQRDQGNGFCVFNNVAIAAEYAKKKYK--LERILIVDWDVHHGQGIQYIFEEDPSVLYFSWHRYEHKTFWPYLSESDYNAVGRGKGTGFNINLPWNKVGMSNADYIAVFFHVLLPLAFEFNPELVLVSAGYDSAIGDPEGRMCATPECFSHLTSMLMNLADGKLCAVLEGGYNLRSLAESVCMTVRTLLGDPLPKLTGEMTPCHSALESIQNVRAAHSPYWKCL 359          
BLAST of Histone deacetylase,putative vs. Ensembl Xenopus
Match: ENSXETT00000036079.1 (histone deacetylase 10 [Source:NCBI gene;Acc:100497245])

HSP 1 Score: 348.977 bits (894), Expect = 1.525e-105
Identity = 164/367 (44.69%), Postives = 240/367 (65.40%), Query Frame = 2
Query:  263 TAFVYDEQMLLHSNMWDN--LYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSV--NVADNHEP 1351
            TA VYDE+M+ +  +WD+     E P+RL   Y+ + + +L++ C ++  +E  +E I   HS  ++++++ TQTM   +L+E+S ++  VFF  N+   + +S G T++++ AVL    +NG  L+RPPGHH+   + +GFC+FNNV IAA+YA+  Y  ++ILIVDWDVHHG   QY F     VLY S HRYE   FWP L ES+Y+ +G  +G G+NIN+P NK  M+N+DY+++F  ++LP+A+E+NPELVL+SAG+DSAIG PEG M   P CF+H+T  LM+LA G++  +LEGGY + SL +SV +T+ TL G   PKL     PC S  E+IQN       +WK L    N+   H+P
Sbjct:    5 TALVYDEEMMSYKLLWDDQECSIEVPERLSSSYKRLQDYDLVKRCTQLPVREATDEEITLVHSSDYLEVVKSTQTMNEKELEEISRKYTAVFFHQNSFRCAKLSLGGTLQLVDAVLSGEVQNGMALVRPPGHHSQRDQGNGFCVFNNVAIAAEYAKKKYKLERILIVDWDVHHGQGIQYIFEEDPSVLYFSWHRYEHKTFWPYLSESDYNAVGRGKGTGFNINLPWNKVGMSNADYIAVFFHVLLPLAFEFNPELVLVSAGYDSAIGDPEGRMCATPECFSHLTSMLMNLADGKLCAVLEGGYNLRSLAESVCMTVRTLLGDPLPKLTGEMTPCHSALESIQNVRAAHSPYWKCLLCDGNLRSAHDP 371          

HSP 2 Score: 289.656 bits (740), Expect = 6.446e-84
Identity = 144/357 (40.34%), Postives = 222/357 (62.18%), Query Frame = 2
Query: 1517 TCFVYDCRMENH---MNERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIIN-FPINKSGIEAIRKTLEYQKPYWKCL 2575
            T  VYD  M ++    +++    E P R    ++ L+D  L+ RC QL  R A+ +EI L+HS +Y+E + +    +         ++ +++ +Q+S+  A LS G  L ++D V S   +NG A++RPPGHH++ +   GFC FNNVAIAA YA  KY   +++ILIVDWDVHHG G Q+ F  + +VLY S HRY++  F+P  ++   +AVG     GFN+N+ WNK  + +++YI+ F ++++P++ EFNP+LV+VSAG+D+A GDP G +  TPECF ++T ML +LA+GK+   LEGGYNL  +++ +   V +LLG P  ++        S +E+I+       PYWKCL
Sbjct:    5 TALVYDEEMMSYKLLWDDQECSIEVPERLSSSYKRLQDYDLVKRCTQLPVREATDEEITLVHSSDYLEVVKSTQTMNEKELEEISRKYTAVFFHQNSFRCAKLSLGGTLQLVDAVLSGEVQNGMALVRPPGHHSQRDQGNGFCVFNNVAIAAEYAKKKYK--LERILIVDWDVHHGQGIQYIFEEDPSVLYFSWHRYEHKTFWPYLSESDYNAVGRGKGTGFNINLPWNKVGMSNADYIAVFFHVLLPLAFEFNPELVLVSAGYDSAIGDPEGRMCATPECFSHLTSMLMNLADGKLCAVLEGGYNLRSLAESVCMTVRTLLGDPLPKLTGEMTPCHSALESIQNVRAAHSPYWKCL 359          
BLAST of Histone deacetylase,putative vs. Ensembl Xenopus
Match: ENSXETT00000022845.1 (histone deacetylase 10 [Source:NCBI gene;Acc:100497245])

HSP 1 Score: 333.569 bits (854), Expect = 1.369e-101
Identity = 157/353 (44.48%), Postives = 230/353 (65.16%), Query Frame = 2
Query:  305 MWDN--LYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSV--NVADNHEP 1351
            +WD+     E P+RL   Y+ + + +L++ C ++  +E  +E I   HS  ++++++ TQTM   +L+E+S ++  VFF  N+   + +S G T++++ AVL    +NG  L+RPPGHH+   + +GFC+FNNV IAA+YA+  Y  ++ILIVDWDVHHG   QY F     VLY S HRYE   FWP L ES+Y+ +G  +G G+NIN+P NK  M+N+DY+++F  ++LP+A+E+NPELVL+SAG+DSAIG PEG M   P CF+H+T  LM+LA G++  +LEGGY + SL +SV +T+ TL G   PKL     PC S  E+IQN       +WK L    N+   H+P
Sbjct:    6 LWDDQECSIEVPERLSSSYKRLQDYDLVKRCTQLPVREATDEEITLVHSSDYLEVVKSTQTMNEKELEEISRKYTAVFFHQNSFRCAKLSLGGTLQLVDAVLSGEVQNGMALVRPPGHHSQRDQGNGFCVFNNVAIAAEYAKKKYKLERILIVDWDVHHGQGIQYIFEEDPSVLYFSWHRYEHKTFWPYLSESDYNAVGRGKGTGFNINLPWNKVGMSNADYIAVFFHVLLPLAFEFNPELVLVSAGYDSAIGDPEGRMCATPECFSHLTSMLMNLADGKLCAVLEGGYNLRSLAESVCMTVRTLLGDPLPKLTGEMTPCHSALESIQNVRAAHSPYWKCLLCDGNLRSAHDP 358          

HSP 2 Score: 285.419 bits (729), Expect = 4.584e-84
Identity = 139/334 (41.62%), Postives = 212/334 (63.47%), Query Frame = 2
Query: 1577 ESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIIN-FPINKSGIEAIRKTLEYQKPYWKCL 2575
            E P R    ++ L+D  L+ RC QL  R A+ +EI L+HS +Y+E + +    +         ++ +++ +Q+S+  A LS G  L ++D V S   +NG A++RPPGHH++ +   GFC FNNVAIAA YA  KY   +++ILIVDWDVHHG G Q+ F  + +VLY S HRY++  F+P  ++   +AVG     GFN+N+ WNK  + +++YI+ F ++++P++ EFNP+LV+VSAG+D+A GDP G +  TPECF ++T ML +LA+GK+   LEGGYNL  +++ +   V +LLG P  ++        S +E+I+       PYWKCL
Sbjct:   15 EVPERLSSSYKRLQDYDLVKRCTQLPVREATDEEITLVHSSDYLEVVKSTQTMNEKELEEISRKYTAVFFHQNSFRCAKLSLGGTLQLVDAVLSGEVQNGMALVRPPGHHSQRDQGNGFCVFNNVAIAAEYAKKKYK--LERILIVDWDVHHGQGIQYIFEEDPSVLYFSWHRYEHKTFWPYLSESDYNAVGRGKGTGFNINLPWNKVGMSNADYIAVFFHVLLPLAFEFNPELVLVSAGYDSAIGDPEGRMCATPECFSHLTSMLMNLADGKLCAVLEGGYNLRSLAESVCMTVRTLLGDPLPKLTGEMTPCHSALESIQNVRAAHSPYWKCL 346          
BLAST of Histone deacetylase,putative vs. Ensembl Mouse
Match: Hdac6 (histone deacetylase 6 [Source:MGI Symbol;Acc:MGI:1333752])

HSP 1 Score: 716.457 bits (1848), Expect = 0.000e+0
Identity = 413/1115 (37.04%), Postives = 595/1115 (53.36%), Query Frame = 2
Query:  218 GLYDNIELRINFPNKTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKENDQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMN-ERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINF-PINKSGIEAIRKTLEYQKPYWKCLKFYE----------PLVVTYTEISPNQTNPAALDNIVQIDTNTLAESVRQLGIVEVTFQTEQSIEETLSQPRN---DTFITEPNSSNPIIHLPPI-VSSDNAVEVPATTSINSTTHATQNISANFLSVD----------------QSSGATPVSA---------------NVSRVINEGNSV--GLVLQDIMNLSGVSNSDIHHFLGLTSNDPLPERVYAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQVFCGRFVQAHMMQHFQNTRHAIVLSFVDLSSWCYECDSYVHNECLNHAKREAHIAKFGVPQP 3415
            GL  N E R+  P  T  V+DEQ+     +WD+ + E P+RL    E +    LL  C+  QA+  + E +   HS  ++ L+E TQ M   +L+ L+  +D V+   N+   + ++ GS + ++ A++    +NG  +IRPPGHHA  +   G+C+FN++ +AA+YAQ  +  Q++LIVDWDVHHG  TQ+ F     VLY SIHRYE G FWP L+ SN+  IG  +G+GY IN+P N+T M ++DY++ F  I+LP+A E+ P+LVL++AGFD+  G P+G M   PA FAH+TH LM LA G++++ LEGGY + +L   V  +L TL G   P LE    PC S + +I   L+ L  FW+ L  +V    E   E      E      +   LP++  P                          N+T  VYD +M +H N   + HPE+P+R   I   L +  L +RC  L +R A   E+   HS  YVE L    +      H     F+SIYI   ++  A L+ G    +++ V S    NG A++RPPGHHAE N   GFCFFN+VA+AA +A      ++ +ILIVDWDVHHGNGTQH F  + +VLY+SLHRYD G FFP   +G+ S VG D   GF VN+ WN   + D++Y++A+  +V+PI++EFNP+LV++SAGFDAA+GDPLGG  VTPE + ++T +L  LA G++IL LEGGYNL  IS+ M+ C  SLLG P  Q+    P     + +I + ++  + YW+ L+  +           LV+      P   +P +   +         ESVR+      T       E TL Q ++      + +  SS        + +++       ATT + ++  A +N      SV+                Q++GA+P+                  +SR   E +    GL+ +        S      F    + D      YAV PL WC HL  V   P+A  +DV+  C  C + +ENW+CLTCYQV+C R+V AHM+ H + + H +VLS VDLS+WCY C +YVH+E L   K  AH  KFG   P
Sbjct:   72 GLDLNPETRV--PVGTGLVFDEQLNDFHCLWDDSFPESPERLHAIREQLILEGLLGRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLAETYDSVYLHPNSYSCACLATGSVLRLVDALMGAEIRNGMAVIRPPGHHAQHNLMDGYCMFNHLAVAARYAQKKHRIQRVLIVDWDVHHGQGTQFIFDQDPSVLYFSIHRYEHGRFWPHLKASNWSTIGFGQGQGYTINVPWNQTGMRDADYIAAFLHILLPVASEFQPQLVLVAAGFDALHGDPKGEMAATPAGFAHLTHLLMGLAGGKLILSLEGGYNLRALAKGVSASLHTLLGDPCPMLESCVVPCASAQTSIYCTLEALEPFWEVLERSVETQEEDEVEEAVLEEEEEEGGWEATALPMDTWP-----------------------LLQNRTGLVYDEKMMSHCNLWDNHHPETPQRILRIMCHLEEVGLAARCLILPARPALDSELLTCHSAEYVEHLRTTEKMKTRDLHREGANFDSIYICPSTFACAKLATGAACRLVEAVLSGEVLNGIAVVRPPGHHAEPNAACGFCFFNSVAVAARHAQIIAGRAL-RILIVDWDVHHGNGTQHIFEDDPSVLYVSLHRYDRGTFFPMGDEGASSQVGRDAGIGFTVNVPWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLISAGFDAAQGDPLGGCQVTPEGYAHLTHLLMGLAGGRIILILEGGYNLASISESMAACTHSLLGDPPPQLTLLRPPQSGALVSISEVIQVHRKYWRSLRLMKMEDKEECSSSRLVIKKL---PPTASPVSAKEMTTPKGKVPEESVRK------TIAALPGKESTLGQAKSKMAKAVLAQGQSSEQAAKGTTLDLATSKETVGGATTDLWASAAAPENFPNQTTSVEALGETEPTPPASHTNKQTTGASPLQGVTAQQSLQLGVLSTLELSREAEEAHDSEEGLLGEAAGGQDMNSLMLTQGFGDFNTQDVF----YAVTPLSWCPHLMAVCPIPAAG-LDVSQPCKTCGTVQENWVCLTCYQVYCSRYVNAHMVCHHEASEHPLVLSCVDLSTWCYVCQAYVHHEDLQDVKNAAHQNKFGEDMP 1146          
BLAST of Histone deacetylase,putative vs. Ensembl Mouse
Match: Hdac6 (histone deacetylase 6 [Source:MGI Symbol;Acc:MGI:1333752])

HSP 1 Score: 716.457 bits (1848), Expect = 0.000e+0
Identity = 413/1115 (37.04%), Postives = 595/1115 (53.36%), Query Frame = 2
Query:  218 GLYDNIELRINFPNKTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKENDQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMN-ERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINF-PINKSGIEAIRKTLEYQKPYWKCLKFYE----------PLVVTYTEISPNQTNPAALDNIVQIDTNTLAESVRQLGIVEVTFQTEQSIEETLSQPRN---DTFITEPNSSNPIIHLPPI-VSSDNAVEVPATTSINSTTHATQNISANFLSVD----------------QSSGATPVSA---------------NVSRVINEGNSV--GLVLQDIMNLSGVSNSDIHHFLGLTSNDPLPERVYAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQVFCGRFVQAHMMQHFQNTRHAIVLSFVDLSSWCYECDSYVHNECLNHAKREAHIAKFGVPQP 3415
            GL  N E R+  P  T  V+DEQ+     +WD+ + E P+RL    E +    LL  C+  QA+  + E +   HS  ++ L+E TQ M   +L+ L+  +D V+   N+   + ++ GS + ++ A++    +NG  +IRPPGHHA  +   G+C+FN++ +AA+YAQ  +  Q++LIVDWDVHHG  TQ+ F     VLY SIHRYE G FWP L+ SN+  IG  +G+GY IN+P N+T M ++DY++ F  I+LP+A E+ P+LVL++AGFD+  G P+G M   PA FAH+TH LM LA G++++ LEGGY + +L   V  +L TL G   P LE    PC S + +I   L+ L  FW+ L  +V    E   E      E      +   LP++  P                          N+T  VYD +M +H N   + HPE+P+R   I   L +  L +RC  L +R A   E+   HS  YVE L    +      H     F+SIYI   ++  A L+ G    +++ V S    NG A++RPPGHHAE N   GFCFFN+VA+AA +A      ++ +ILIVDWDVHHGNGTQH F  + +VLY+SLHRYD G FFP   +G+ S VG D   GF VN+ WN   + D++Y++A+  +V+PI++EFNP+LV++SAGFDAA+GDPLGG  VTPE + ++T +L  LA G++IL LEGGYNL  IS+ M+ C  SLLG P  Q+    P     + +I + ++  + YW+ L+  +           LV+      P   +P +   +         ESVR+      T       E TL Q ++      + +  SS        + +++       ATT + ++  A +N      SV+                Q++GA+P+                  +SR   E +    GL+ +        S      F    + D      YAV PL WC HL  V   P+A  +DV+  C  C + +ENW+CLTCYQV+C R+V AHM+ H + + H +VLS VDLS+WCY C +YVH+E L   K  AH  KFG   P
Sbjct:   72 GLDLNPETRV--PVGTGLVFDEQLNDFHCLWDDSFPESPERLHAIREQLILEGLLGRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLAETYDSVYLHPNSYSCACLATGSVLRLVDALMGAEIRNGMAVIRPPGHHAQHNLMDGYCMFNHLAVAARYAQKKHRIQRVLIVDWDVHHGQGTQFIFDQDPSVLYFSIHRYEHGRFWPHLKASNWSTIGFGQGQGYTINVPWNQTGMRDADYIAAFLHILLPVASEFQPQLVLVAAGFDALHGDPKGEMAATPAGFAHLTHLLMGLAGGKLILSLEGGYNLRALAKGVSASLHTLLGDPCPMLESCVVPCASAQTSIYCTLEALEPFWEVLERSVETQEEDEVEEAVLEEEEEEGGWEATALPMDTWP-----------------------LLQNRTGLVYDEKMMSHCNLWDNHHPETPQRILRIMCHLEEVGLAARCLILPARPALDSELLTCHSAEYVEHLRTTEKMKTRDLHREGANFDSIYICPSTFACAKLATGAACRLVEAVLSGEVLNGIAVVRPPGHHAEPNAACGFCFFNSVAVAARHAQIIAGRAL-RILIVDWDVHHGNGTQHIFEDDPSVLYVSLHRYDRGTFFPMGDEGASSQVGRDAGIGFTVNVPWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLISAGFDAAQGDPLGGCQVTPEGYAHLTHLLMGLAGGRIILILEGGYNLASISESMAACTHSLLGDPPPQLTLLRPPQSGALVSISEVIQVHRKYWRSLRLMKMEDKEECSSSRLVIKKL---PPTASPVSAKEMTTPKGKVPEESVRK------TIAALPGKESTLGQAKSKMAKAVLAQGQSSEQAAKGTTLDLATSKETVGGATTDLWASAAAPENFPNQTTSVEALGETEPTPPASHTNKQTTGASPLQGVTAQQSLQLGVLSTLELSREAEEAHDSEEGLLGEAAGGQDMNSLMLTQGFGDFNTQDVF----YAVTPLSWCPHLMAVCPIPAAG-LDVSQPCKTCGTVQENWVCLTCYQVYCSRYVNAHMVCHHEASEHPLVLSCVDLSTWCYVCQAYVHHEDLQDVKNAAHQNKFGEDMP 1146          
BLAST of Histone deacetylase,putative vs. Ensembl Mouse
Match: Hdac6 (histone deacetylase 6 [Source:MGI Symbol;Acc:MGI:1333752])

HSP 1 Score: 619.002 bits (1595), Expect = 0.000e+0
Identity = 322/793 (40.61%), Postives = 462/793 (58.26%), Query Frame = 2
Query:  215 HGLYDNIELRINFPNKTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKENDQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMN-ERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINF-PINKSGIEAIRKTLEYQKPYWKCLKFYE 2587
             GL  N E R+  P  T  V+DEQ+     +WD+ + E P+RL    E +    LL  C+  QA+  + E +   HS  ++ L+E TQ M   +L+ L+  +D V+   N+   + ++ GS + ++ A++    +NG  +IRPPGHHA  +   G+C+FN++ +AA+YAQ  +  Q++LIVDWDVHHG  TQ+ F     VLY SIHRYE G FWP L+ SN+  IG  +G+GY IN+P N+T M ++DY++ F  I+LP+A E+ P+LVL++AGFD+  G P+G M   PA FAH+TH LM LA G++++ LEGGY + +L   V  +L TL G   P LE    PC S + +I   L+ L  FW+ L  +V    E   E      E      +   LP++  P                          N+T  VYD +M +H N   + HPE+P+R   I   L +  L +RC  L +R A   E+   HS  YVE L    +      H     F+SIYI   ++  A L+ G    +++ V S    NG A++RPPGHHAE N   GFCFFN+VA+AA +A      ++ +ILIVDWDVHHGNGTQH F  + +VLY+SLHRYD G FFP   +G+ S VG D   GF VN+ WN   + D++Y++A+  +V+PI++EFNP+LV++SAGFDAA+GDPLGG  VTPE + ++T +L  LA G++IL LEGGYNL  IS+ M+ C  SLLG P  Q+    P     + +I + ++  + YW+ L+  +
Sbjct:   71 QGLDLNPETRV--PVGTGLVFDEQLNDFHCLWDDSFPESPERLHAIREQLILEGLLGRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLAETYDSVYLHPNSYSCACLATGSVLRLVDALMGAEIRNGMAVIRPPGHHAQHNLMDGYCMFNHLAVAARYAQKKHRIQRVLIVDWDVHHGQGTQFIFDQDPSVLYFSIHRYEHGRFWPHLKASNWSTIGFGQGQGYTINVPWNQTGMRDADYIAAFLHILLPVASEFQPQLVLVAAGFDALHGDPKGEMAATPAGFAHLTHLLMGLAGGKLILSLEGGYNLRALAKGVSASLHTLLGDPCPMLESCVVPCASAQTSIYCTLEALEPFWEVLERSVETQEEDEVEEAVLEEEEEEGGWEATALPMDTWP-----------------------LLQNRTGLVYDEKMMSHCNLWDNHHPETPQRILRIMCHLEEVGLAARCLILPARPALDSELLTCHSAEYVEHLRTTEKMKTRDLHREGANFDSIYICPSTFACAKLATGAACRLVEAVLSGEVLNGIAVVRPPGHHAEPNAACGFCFFNSVAVAARHAQIIAGRAL-RILIVDWDVHHGNGTQHIFEDDPSVLYVSLHRYDRGTFFPMGDEGASSQVGRDAGIGFTVNVPWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLISAGFDAAQGDPLGGCQVTPEGYAHLTHLLMGLAGGRIILILEGGYNLASISESMAACTHSLLGDPPPQLTLLRPPQSGALVSISEVIQVHRKYWRSLRLMK 837          

HSP 2 Score: 299.671 bits (766), Expect = 5.879e-85
Identity = 154/422 (36.49%), Postives = 236/422 (55.92%), Query Frame = 2
Query:  257 NKTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAK-EIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQ-KILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKENDQLNHKIYELRTKNAFNNYPNK 1516
            N+T  VYDE+M+ H N+WDN + E P R+      + E  L   C+ + A+  +D+EL+   HS  +V+ +  T+ M    L    +  D ++   +T   + ++ G+   +++AVL     NG  ++RPPGHHA  + A GFC FN+V +AA++AQ+      +ILIVDWDVHHGN TQ+ F +   VLY+S+HRY+ G F+P   E     +G + G G+ +N+P N   M ++DYL+ +H ++LPIAYE+NPELVLISAGFD+A G P G   V P  +AH+TH LM LA GR++++LEGGY + S+ +S+     +L G  PP+L     P      +I   ++    +W+SL +   ++ E          E + +   + KLP   +P   KE      K+ E   +      P K
Sbjct:  478 NRTGLVYDEKMMSHCNLWDNHHPETPQRILRIMCHLEEVGLAARCLILPARPALDSELLT-CHSAEYVEHLRTTEKMKTRDLHREGANFDSIYICPSTFACAKLATGAACRLVEAVLSGEVLNGIAVVRPPGHHAEPNAACGFCFFNSVAVAARHAQIIAGRALRILIVDWDVHHGNGTQHIFEDDPSVLYVSLHRYDRGTFFPMGDEGASSQVGRDAGIGFTVNVPWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLISAGFDAAQGDPLGGCQVTPEGYAHLTHLLMGLAGGRIILILEGGYNLASISESMAACTHSLLGDPPPQLTLLRPPQSGALVSISEVIQVHRKYWRSLRLMKMEDKE----------ECSSSRLVIKKLPPTASPVSAKEMTTPKGKVPEESVRKTIAALPGK 888          
BLAST of Histone deacetylase,putative vs. Ensembl Mouse
Match: Hdac10 (histone deacetylase 10 [Source:MGI Symbol;Acc:MGI:2158340])

HSP 1 Score: 341.658 bits (875), Expect = 5.962e-103
Identity = 169/381 (44.36%), Postives = 233/381 (61.15%), Query Frame = 2
Query:  263 TAFVYDEQMLLHSNMWDN--LYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVA-----DNHEPYPEYLRHLPES 1384
            TA VY E M     +WD+     E P+RL    +G+ +  L E C+ + A E   E +   HS  ++ L++ TQT+   +L  LS Q++ V+F  +T   + ++AG+ ++++ AVL     NG  L+RPPGHH+  + A+GFC+FNNV +AAK+A+  Y  Q+ILIVDWDVHHG   QY F +   VLY S HRYE G+FWP L ES+ D +G  +G+G+ +N+P N+  M N+DYL+ F  ++LP+A+E++PELVL+SAGFDSAIG PEG M   P CFAH+T  L  LA GR+  +LEGGY +ESL  SV + + TL G   P L     PC S  E+IQ+       +W SL  NVA       H P    LR L ES
Sbjct:    3 TALVYHEDMTATRLLWDDPECEIECPERLTAALDGLRQRGLEERCLCLSACEASEEELGLVHSPEYIALVQKTQTLDKEELHALSKQYNAVYFHPDTFHCARLAAGAALQLVDAVLTGAVHNGLALVRPPGHHSQRAAANGFCVFNNVALAAKHAKQKYGLQRILIVDWDVHHGQGIQYIFNDDPSVLYFSWHRYEHGSFWPFLPESDADAVGQGQGQGFTVNLPWNQVGMGNADYLAAFLHVLLPLAFEFDPELVLVSAGFDSAIGDPEGQMQATPECFAHLTQLLQVLAGGRICAVLEGGYHLESLAQSVCMMVQTLLGDPTPPLLGLMVPCQSALESIQSVQTAQTPYWTSLQQNVAPVLSSSTHSPEERSLRLLGES 383          

HSP 2 Score: 283.493 bits (724), Expect = 5.103e-82
Identity = 138/357 (38.66%), Postives = 221/357 (61.90%), Query Frame = 2
Query: 1577 ESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTI----YHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINFPIN-KSGIEAIRKTLEYQKPYWKCLKFYEPLVVTYTEISPNQTN 2632
            E P R     + LR   L  RC  L +  AS++E+GL+HSP Y+     + Q++ T+     H   +++N++Y +  ++  A L+ G  L ++D V +    NG A++RPPGHH++     GFC FNNVA+AA +A  KY   +++ILIVDWDVHHG G Q+ F  + +VLY S HRY++G F+P   +    AVG    +GF VN+ WN+  + +++Y++AF+++++P++ EF+P+LV+VSAGFD+A GDP G +  TPECF ++TQ+L  LA G++   LEGGY+L  ++  +   V +LLG PT  ++   +  +S +E+I+     Q PYW  L+     V++ +  SP + +
Sbjct:   26 ECPERLTAALDGLRQRGLEERCLCLSACEASEEELGLVHSPEYI----ALVQKTQTLDKEELHALSKQYNAVYFHPDTFHCARLAAGAALQLVDAVLTGAVHNGLALVRPPGHHSQRAAANGFCVFNNVALAAKHAKQKYG--LQRILIVDWDVHHGQGIQYIFNDDPSVLYFSWHRYEHGSFWPFLPESDADAVGQGQGQGFTVNLPWNQVGMGNADYLAAFLHVLLPLAFEFDPELVLVSAGFDSAIGDPEGQMQATPECFAHLTQLLQVLAGGRICAVLEGGYHLESLAQSVCMMVQTLLGDPTPPLLGLMVPCQSALESIQSVQTAQTPYWTSLQQNVAPVLSSSTHSPEERS 376          
BLAST of Histone deacetylase,putative vs. Ensembl Mouse
Match: Hdac9 (histone deacetylase 9 [Source:MGI Symbol;Acc:MGI:1931221])

HSP 1 Score: 300.827 bits (769), Expect = 3.534e-85
Identity = 160/385 (41.56%), Postives = 231/385 (60.00%), Query Frame = 2
Query: 1517 TCFVYDCRMENHM---NERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNY-----VESLGNICQESPTIYHLFEEEF-------------NSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKR---PVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARG--DPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQI----INFPINKSGIEAIRKTLEYQKPYWKCLKF 2581
            T   YD  M  H       + HPE   R Q I+  L++  LLS+C++++ R AS +EI L+HS ++        L     +  T+      +F             ++I+   HS  +A ++ G ++ +  +V S   +NGFA++RPPGHHAE +  +GFCFFN+VAI A Y   + +  I KILIVD DVHHGNGTQ  F+ + ++LYISLHRYD G FFPGS  G+P+ VG    EG+NVNIAW      P+ D EY+ AF  +VMP++ EF+PD+V+VSAGFDA  G   PLGG  VT +CFG++T+ L +LANG+V LALEGG++L  I D    C+++LLG     +    ++  +N +   +++KT++ Q  YWK +K 
Sbjct:  590 TGIAYDPLMLKHQCICGSSTTHPEHAGRIQSIWSRLQETGLLSKCERIQGRKASLEEIQLVHSEHHSLLYGTSPLDGQKLDPRTLLGDDSRKFFSSLPCGGLGVDSDTIWNELHSSGAARMAVGCVIELASKVASGELKNGFAVVRPPGHHAEESAAMGFCFFNSVAITAKYLRDQLN--ISKILIVDLDVHHGNGTQQAFYADPSILYISLHRYDEGNFFPGS--GAPNEVGVGLGEGYNVNIAWTGGLDPPMGDVEYLEAFRTVVMPVAREFDPDMVLVSAGFDALEGHTPPLGGYKVTAKCFGHLTKQLMTLANGRVALALEGGHDLTAICDASEACINALLGNEPGPLEEDALHQSVNTNAAASLQKTIDIQSKYWKSIKM 970          

HSP 2 Score: 233.032 bits (593), Expect = 2.353e-62
Identity = 138/387 (35.66%), Postives = 203/387 (52.45%), Query Frame = 2
Query:  263 TAFVYDEQMLLHSNMWDN--LYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIE---------DTQTM---------TAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLN---KTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIG--CPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSV----KETIQNCLKFLHFFWKSLSVNVA 1336
            T   YD  ML H  +  +   + E   R++  +  + ET LL  C RIQ ++   E I   HS+ H  L           D +T+         +++    L    D ++ + ++  A+ ++ G  IE+   V     KNGF ++RPPGHHA ES A GFC FN+V I AKY +   +  KILIVD DVHHGN TQ  FY    +LYIS+HRY++GNF+P     N   +G   G GYN+NI         M + +YL  F ++++P+A E++P++VL+SAGFD+  G   P G   V   CF H+T +LM LA GRV + LEGG+ + ++ D+    +  L G  P  LE+ D    SV      ++Q  +     +WKS+ +  A
Sbjct:  590 TGIAYDPLMLKHQCICGSSTTHPEHAGRIQSIWSRLQETGLLSKCERIQGRKASLEEIQLVHSEHHSLLYGTSPLDGQKLDPRTLLGDDSRKFFSSLPCGGLGVDSDTIWNELHSSGAARMAVGCVIELASKVASGELKNGFAVVRPPGHHAEESAAMGFCFFNSVAITAKYLRDQLNISKILIVDLDVHHGNGTQQAFYADPSILYISLHRYDEGNFFPGSGAPN--EVGVGLGEGYNVNIAWTGGLDPPMGDVEYLEAFRTVVMPVAREFDPDMVLVSAGFDALEGHTPPLGGYKVTAKCFGHLTKQLMTLANGRVALALEGGHDLTAICDASEACINALLGNEPGPLEE-DALHQSVNTNAAASLQKTIDIQSKYWKSIKMVAA 973          
BLAST of Histone deacetylase,putative vs. UniProt/SwissProt
Match: sp|Q9Z2V5|HDAC6_MOUSE (Histone deacetylase 6 OS=Mus musculus OX=10090 GN=Hdac6 PE=1 SV=3)

HSP 1 Score: 716.457 bits (1848), Expect = 0.000e+0
Identity = 413/1115 (37.04%), Postives = 595/1115 (53.36%), Query Frame = 2
Query:  218 GLYDNIELRINFPNKTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKENDQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMN-ERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINF-PINKSGIEAIRKTLEYQKPYWKCLKFYE----------PLVVTYTEISPNQTNPAALDNIVQIDTNTLAESVRQLGIVEVTFQTEQSIEETLSQPRN---DTFITEPNSSNPIIHLPPI-VSSDNAVEVPATTSINSTTHATQNISANFLSVD----------------QSSGATPVSA---------------NVSRVINEGNSV--GLVLQDIMNLSGVSNSDIHHFLGLTSNDPLPERVYAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQVFCGRFVQAHMMQHFQNTRHAIVLSFVDLSSWCYECDSYVHNECLNHAKREAHIAKFGVPQP 3415
            GL  N E R+  P  T  V+DEQ+     +WD+ + E P+RL    E +    LL  C+  QA+  + E +   HS  ++ L+E TQ M   +L+ L+  +D V+   N+   + ++ GS + ++ A++    +NG  +IRPPGHHA  +   G+C+FN++ +AA+YAQ  +  Q++LIVDWDVHHG  TQ+ F     VLY SIHRYE G FWP L+ SN+  IG  +G+GY IN+P N+T M ++DY++ F  I+LP+A E+ P+LVL++AGFD+  G P+G M   PA FAH+TH LM LA G++++ LEGGY + +L   V  +L TL G   P LE    PC S + +I   L+ L  FW+ L  +V    E   E      E      +   LP++  P                          N+T  VYD +M +H N   + HPE+P+R   I   L +  L +RC  L +R A   E+   HS  YVE L    +      H     F+SIYI   ++  A L+ G    +++ V S    NG A++RPPGHHAE N   GFCFFN+VA+AA +A      ++ +ILIVDWDVHHGNGTQH F  + +VLY+SLHRYD G FFP   +G+ S VG D   GF VN+ WN   + D++Y++A+  +V+PI++EFNP+LV++SAGFDAA+GDPLGG  VTPE + ++T +L  LA G++IL LEGGYNL  IS+ M+ C  SLLG P  Q+    P     + +I + ++  + YW+ L+  +           LV+      P   +P +   +         ESVR+      T       E TL Q ++      + +  SS        + +++       ATT + ++  A +N      SV+                Q++GA+P+                  +SR   E +    GL+ +        S      F    + D      YAV PL WC HL  V   P+A  +DV+  C  C + +ENW+CLTCYQV+C R+V AHM+ H + + H +VLS VDLS+WCY C +YVH+E L   K  AH  KFG   P
Sbjct:   72 GLDLNPETRV--PVGTGLVFDEQLNDFHCLWDDSFPESPERLHAIREQLILEGLLGRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLAETYDSVYLHPNSYSCACLATGSVLRLVDALMGAEIRNGMAVIRPPGHHAQHNLMDGYCMFNHLAVAARYAQKKHRIQRVLIVDWDVHHGQGTQFIFDQDPSVLYFSIHRYEHGRFWPHLKASNWSTIGFGQGQGYTINVPWNQTGMRDADYIAAFLHILLPVASEFQPQLVLVAAGFDALHGDPKGEMAATPAGFAHLTHLLMGLAGGKLILSLEGGYNLRALAKGVSASLHTLLGDPCPMLESCVVPCASAQTSIYCTLEALEPFWEVLERSVETQEEDEVEEAVLEEEEEEGGWEATALPMDTWP-----------------------LLQNRTGLVYDEKMMSHCNLWDNHHPETPQRILRIMCHLEEVGLAARCLILPARPALDSELLTCHSAEYVEHLRTTEKMKTRDLHREGANFDSIYICPSTFACAKLATGAACRLVEAVLSGEVLNGIAVVRPPGHHAEPNAACGFCFFNSVAVAARHAQIIAGRAL-RILIVDWDVHHGNGTQHIFEDDPSVLYVSLHRYDRGTFFPMGDEGASSQVGRDAGIGFTVNVPWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLISAGFDAAQGDPLGGCQVTPEGYAHLTHLLMGLAGGRIILILEGGYNLASISESMAACTHSLLGDPPPQLTLLRPPQSGALVSISEVIQVHRKYWRSLRLMKMEDKEECSSSRLVIKKL---PPTASPVSAKEMTTPKGKVPEESVRK------TIAALPGKESTLGQAKSKMAKAVLAQGQSSEQAAKGTTLDLATSKETVGGATTDLWASAAAPENFPNQTTSVEALGETEPTPPASHTNKQTTGASPLQGVTAQQSLQLGVLSTLELSREAEEAHDSEEGLLGEAAGGQDMNSLMLTQGFGDFNTQDVF----YAVTPLSWCPHLMAVCPIPAAG-LDVSQPCKTCGTVQENWVCLTCYQVYCSRYVNAHMVCHHEASEHPLVLSCVDLSTWCYVCQAYVHHEDLQDVKNAAHQNKFGEDMP 1146          
BLAST of Histone deacetylase,putative vs. UniProt/SwissProt
Match: sp|Q9UBN7|HDAC6_HUMAN (Histone deacetylase 6 OS=Homo sapiens OX=9606 GN=HDAC6 PE=1 SV=2)

HSP 1 Score: 602.438 bits (1552), Expect = 0.000e+0
Identity = 315/777 (40.54%), Postives = 454/777 (58.43%), Query Frame = 2
Query:  263 TAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKENDQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMN-ERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINFPINKSG-IEAIRKTLEYQKPYWKCLKFYE 2587
            T  V DEQ+     +WD+ + E P+RL    E + +  LL+ C+  QA+  + E +   HS  ++ L+E TQ M   +L+ L+  +D V+   N+   + +++GS + ++ AVL    +NG  +IRPPGHHA  S   G+C+FN+V +AA+YAQ  +  +++LIVDWDVHHG  TQ+ F     VLY SIHRYE G FWP L+ SN+   G  +G+GY IN+P N+  M ++DY++ F  ++LP+A E+ P+LVL++AGFD+  G P+G M   PA FA +TH LM LA G++++ LEGGY + +L + V  +L TL G   P LE    PC S + ++   L+ L  FW+ L  +         E             + P LPI            L   + + RT             VYD  M NH N   S HPE P+R   I   L +  L  RC  L  R A++ E+   HS  YV  L    +      H     F+SIYI   ++  A L+ G    +++ V S    NG A++RPPGHHAE +   GFCFFN+VA+AA +A T    ++ +ILIVDWDVHHGNGTQH F  + +VLY+SLHRYD+G FFP   +G+ S +G     GF VN+AWN   + D++Y++A+  +V+PI++EFNP+LV+VSAGFDAARGDPLGG  V+PE + ++T +L  LA+G++IL LEGGYNL  IS+ M+ C  SLLG P   +       SG + +I +T++  + YW+ L+  +
Sbjct:   86 TGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHPNSYSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQKHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATPAGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSAQASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPPVLPI------------LTWPVLQSRTG-----------LVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHAL-RILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMK 838          

HSP 2 Score: 270.011 bits (689), Expect = 4.089e-73
Identity = 138/365 (37.81%), Postives = 211/365 (57.81%), Query Frame = 2
Query:  257 NKTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQ-LNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHE 1348
            ++T  VYD+ M+ H N+WD+ + E P R+      + E  L   C+ +  +      +   HS  +V  +  T+ M   +L   SS  D ++   +T   + ++ G+   +++AVL     NG  ++RPPGHHA +  A GFC FN+V +AA++AQ ++    +ILIVDWDVHHGN TQ+ F +   VLY+S+HRY+ G F+P   E     IG   G G+ +N+  N   M ++DYL+ +H ++LPIAYE+NPELVL+SAGFD+A G P G   V P  +AH+TH LM LA GR++++LEGGY + S+ +S+     +L G  PP L     P      +I   ++    +W+SL V   ++ E
Sbjct:  479 SRTGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVEDRE 843          

HSP 3 Score: 128.257 bits (321), Expect = 2.043e-28
Identity = 88/283 (31.10%), Postives = 132/283 (46.64%), Query Frame = 2
Query: 2615 SPNQTNP------AALDNIVQIDT---NTLAESVRQLGIVEVTFQTEQSIEETLSQPRNDTFITEPNSSNPIIHLPPIVSSDNAVEVPATTSINSTTHATQNISANFLSVDQSS---GATPVSANVSRVINEGNSVGLVLQDIMNLSGVSNSDIHHFLGLTSNDPLPERV--YAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQVFCGRFVQAHMMQHFQNTRHAIVLSFVDLSSWCYECDSYVHNECLNHAKREAHIAKFG--VPQP 3415
            +P+QT        A LD     D     TL ++  +  +   T     S         + T   E      +I  P   S+D+  + P T+ +  TT     IS + L     +   G+    A+ S+   E N +G               D+   + +  +  L ++   YAV PL WC HL  V   P+A  +DV   C  C + +ENW+CL+CYQV+CGR++  HM+QH  N+ H +VLS++DLS+WCY C +YVH++ L   K  AH  KFG  +P P
Sbjct:  947 TPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDH--QTPPTSPVQGTT---PQISPSTLIGSLRTLELGSESQGASESQAPGEENLLG---------EAAGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAG-LDVTQPCGDCGTIQENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYVHHQALLDVKNIAHQNKFGEDMPHP 1214          
BLAST of Histone deacetylase,putative vs. UniProt/SwissProt
Match: sp|Q20296|HDA6_CAEEL (Histone deacetylase 6 OS=Caenorhabditis elegans OX=6239 GN=hda-6 PE=3 SV=2)

HSP 1 Score: 484.182 bits (1245), Expect = 3.943e-152
Identity = 282/780 (36.15%), Postives = 424/780 (54.36%), Query Frame = 2
Query:  296 HSNMWDNLYFERPDRLRVCYEGICETNLLEDC-IRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKENDQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMN-ERSIHPESPRRTQMIFEFLRDNSLLSRCKQLE-SRLASKDEIGLIHSPNYVESLGNI-CQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRS--ENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSL--------LGYPTNQIINFP--INKSGIEAIRKTLEYQKPYWKCLKFYE 2587
            H N     + E  DR+    E + +T +LE C +     EID+  +  +H +S V+ + +++  T   +     ++D VF   N+   +        ++   ++ + A NGF ++RPPGHHA      GFC+FNNV  AA+ A  +   ++ILIVD DVHHG+ TQ  FY+  +VLY SIHR+E G FWP L ES++D+IG+ +G GYN N+ LN+T  T+SDYLSI   ++LP+A +++P  V+ISAGFD+ +G P G M + P  ++H+ + L  LA+GR++V+LEGGY  +    +V   +  L G AP  +E  + P +S  ++  + +  L   W         ++ P    LR       N+  +             E  Q      E    +       +T   ++   + H + E   HPE P RT+ I + LR++ +L +C      R+A+ +EI L+H+   +E L      +   +    E+EFNSIY+ + +   A  + G +L  +DE+    +   N   I+RPPGHHA  +   GFC FNNVA+AA YA  ++    K++LI+DWDVHHGNGTQ  F+ + NV+Y+S+HR+D G F+P       S VG    EG +VN+ ++   + D+EY  AF  ++MPI+++FNPDLV++SAGFDAA  DPLG   VTPE F  MT  L+SLA G++I  LEGGYNL  IS+        L        L     Q    P  I  S I+ IR+    Q+ YW  LK ++
Sbjct:   26 HENTVCPTHPESSDRILKIKEALTKTKILEKCTVLTNFLEIDDADLEVTHDKSMVKDLMESEKKTQEDINSQCEKYDSVFMTENSMKVAKDGVACVRDLTNRIMANEASNGFAVVRPPGHHADSVSPCGFCLFNNVAQAAEEAFFS-GAERILIVDLDVHHGHGTQRIFYDDKRVLYFSIHRHEHGLFWPHLPESDFDHIGSGKGLGYNANLALNETGCTDSDYLSIIFHVLLPLATQFDPHFVIISAGFDALLGDPLGGMCLTPDGYSHILYHLKSLAQGRMLVVLEGGYNHQISAVAVQRCVRVLLGYAPFSIELNEAPKESTVDSCVSLVSVLRHHWNCF------DYFPSRTSLRLAQWPIVNTKVIYNYDPTTRRADTGEIIQDELASTEFTASDVIPTENMETLIYFNEGDDAHFDLEEDNHPEKPARTRRILKTLRESGVLEKCVDRNCERIATNEEIRLVHTKKMLEHLRTTETMKDEELMEEAEKEFNSIYLTRDTLKVARKAVGAVLQSVDEIFEKDAGQRNALVIVRPPGHHASASKSSGFCIFNNVAVAAKYAQRRHKA--KRVLILDWDVHHGNGTQEIFYEDSNVMYMSIHRHDKGNFYPIGEPKDYSDVGEGAGEGMSVNVPFSGVQMGDNEYQMAFQRVIMPIAYQFNPDLVLISAGFDAAVDDPLGEYKVTPETFALMTYQLSSLAGGRIITVLEGGYNLTSISNSAQAVCEVLQNRSMLRRLREEKEQFATKPQKIESSCIKTIREVCAVQQKYWSILKGFQ 796          

HSP 2 Score: 242.662 bits (618), Expect = 6.214e-65
Identity = 119/326 (36.50%), Postives = 197/326 (60.43%), Query Frame = 2
Query:  260 KTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEI-DNELIYYSHSQSHVQLIEDTQTMT-AIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRA--KNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKA 1225
            +T   ++E    H ++ ++ + E+P R R   + + E+ +LE C+    + I  NE I   H++  ++ +  T+TM     ++E   + + ++   +T   +  + G+ ++ +  + +  A  +N   ++RPPGHHA  S++SGFCIFNNV +AAKYAQ  +  +++LI+DWDVHHGN TQ  FY  S V+Y+SIHR++ GNF+P     +Y  +G   G G ++N+P +   M +++Y   F  +I+PIAY++NP+LVLISAGFD+A+  P G   V P  FA MT++L  LA GR++ +LEGGY + S+ +S       L  ++
Sbjct:  426 ETLIYFNEGDDAHFDLEEDNHPEKPARTRRILKTLRESGVLEKCVDRNCERIATNEEIRLVHTKKMLEHLRTTETMKDEELMEEAEKEFNSIYLTRDTLKVARKAVGAVLQSVDEIFEKDAGQRNALVIVRPPGHHASASKSSGFCIFNNVAVAAKYAQRRHKAKRVLILDWDVHHGNGTQEIFYEDSNVMYMSIHRHDKGNFYPIGEPKDYSDVGEGAGEGMSVNVPFSGVQMGDNEYQMAFQRVIMPIAYQFNPDLVLISAGFDAAVDDPLGEYKVTPETFALMTYQLSSLAGGRIITVLEGGYNLTSISNSAQAVCEVLQNRS 751          

HSP 3 Score: 112.464 bits (280), Expect = 9.504e-24
Identity = 54/111 (48.65%), Postives = 66/111 (59.46%), Query Frame = 2
Query: 3086 VYAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQVFCGRFVQAHMMQHFQNTRHAIVLSFVDLSSWCYECDSYVHNECLNHAKREAHIAKFGVPQPS 3418
             +AV PL  C HL +V+  P A +I+   +C+ C    E W CLTCY+  CGRFV  H M H  ++ H + LS  DLS WCY CDSYVHN  L  AK  AH +KFG   PS
Sbjct:  846 AHAVVPLATCPHLKEVKPLPPA-KINARTACSECQIGAEVWTCLTCYKYNCGRFVNEHAMMHHLSSSHPMALSMADLSVWCYPCDSYVHNPALIGAKSAAHESKFGETMPS 955          
BLAST of Histone deacetylase,putative vs. UniProt/SwissProt
Match: sp|Q6P3E7|HDA10_MOUSE (Polyamine deacetylase HDAC10 OS=Mus musculus OX=10090 GN=Hdac10 PE=2 SV=2)

HSP 1 Score: 341.658 bits (875), Expect = 4.170e-102
Identity = 169/381 (44.36%), Postives = 233/381 (61.15%), Query Frame = 2
Query:  263 TAFVYDEQMLLHSNMWDN--LYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVA-----DNHEPYPEYLRHLPES 1384
            TA VY E M     +WD+     E P+RL    +G+ +  L E C+ + A E   E +   HS  ++ L++ TQT+   +L  LS Q++ V+F  +T   + ++AG+ ++++ AVL     NG  L+RPPGHH+  + A+GFC+FNNV +AAK+A+  Y  Q+ILIVDWDVHHG   QY F +   VLY S HRYE G+FWP L ES+ D +G  +G+G+ +N+P N+  M N+DYL+ F  ++LP+A+E++PELVL+SAGFDSAIG PEG M   P CFAH+T  L  LA GR+  +LEGGY +ESL  SV + + TL G   P L     PC S  E+IQ+       +W SL  NVA       H P    LR L ES
Sbjct:    3 TALVYHEDMTATRLLWDDPECEIECPERLTAALDGLRQRGLEERCLCLSACEASEEELGLVHSPEYIALVQKTQTLDKEELHALSKQYNAVYFHPDTFHCARLAAGAALQLVDAVLTGAVHNGLALVRPPGHHSQRAAANGFCVFNNVALAAKHAKQKYGLQRILIVDWDVHHGQGIQYIFNDDPSVLYFSWHRYEHGSFWPFLPESDADAVGQGQGQGFTVNLPWNQVGMGNADYLAAFLHVLLPLAFEFDPELVLVSAGFDSAIGDPEGQMQATPECFAHLTQLLQVLAGGRICAVLEGGYHLESLAQSVCMMVQTLLGDPTPPLLGLMVPCQSALESIQSVQTAQTPYWTSLQQNVAPVLSSSTHSPEERSLRLLGES 383          

HSP 2 Score: 283.493 bits (724), Expect = 3.570e-81
Identity = 138/357 (38.66%), Postives = 221/357 (61.90%), Query Frame = 2
Query: 1577 ESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTI----YHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINFPIN-KSGIEAIRKTLEYQKPYWKCLKFYEPLVVTYTEISPNQTN 2632
            E P R     + LR   L  RC  L +  AS++E+GL+HSP Y+     + Q++ T+     H   +++N++Y +  ++  A L+ G  L ++D V +    NG A++RPPGHH++     GFC FNNVA+AA +A  KY   +++ILIVDWDVHHG G Q+ F  + +VLY S HRY++G F+P   +    AVG    +GF VN+ WN+  + +++Y++AF+++++P++ EF+P+LV+VSAGFD+A GDP G +  TPECF ++TQ+L  LA G++   LEGGY+L  ++  +   V +LLG PT  ++   +  +S +E+I+     Q PYW  L+     V++ +  SP + +
Sbjct:   26 ECPERLTAALDGLRQRGLEERCLCLSACEASEEELGLVHSPEYI----ALVQKTQTLDKEELHALSKQYNAVYFHPDTFHCARLAAGAALQLVDAVLTGAVHNGLALVRPPGHHSQRAAANGFCVFNNVALAAKHAKQKYG--LQRILIVDWDVHHGQGIQYIFNDDPSVLYFSWHRYEHGSFWPFLPESDADAVGQGQGQGFTVNLPWNQVGMGNADYLAAFLHVLLPLAFEFDPELVLVSAGFDSAIGDPEGQMQATPECFAHLTQLLQVLAGGRICAVLEGGYHLESLAQSVCMMVQTLLGDPTPPLLGLMVPCQSALESIQSVQTAQTPYWTSLQQNVAPVLSSSTHSPEERS 376          
BLAST of Histone deacetylase,putative vs. UniProt/SwissProt
Match: sp|Q969S8|HDA10_HUMAN (Polyamine deacetylase HDAC10 OS=Homo sapiens OX=9606 GN=HDAC10 PE=1 SV=1)

HSP 1 Score: 340.117 bits (871), Expect = 1.497e-101
Identity = 159/355 (44.79%), Postives = 223/355 (62.82%), Query Frame = 2
Query:  263 TAFVYDEQMLLHSNMWDN--LYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSL 1321
            TA VY E M     +WD+     ERP+RL    + + +  L + C+R+ A+E   E +   HS  +V L+ +TQ +   +L+ LS Q D ++F  +T   + ++AG+ ++++ AVL    +NG  L+RPPGHH   + A+GFC+FNNV IAA +A+  +   +IL+VDWDVHHG   QY F +   VLY S HRYE G FWP LRES+ D +G  +G G+ +N+P N+  M N+DY++ F  ++LP+A+E++PELVL+SAGFDSAIG PEG M   P CFAH+T  L  LA GRV  +LEGGY +ESL +SV +T+ TL G   P L     PC S  E+IQ+        WKSL
Sbjct:    3 TALVYHEDMTATRLLWDDPECEIERPERLTAALDRLRQRGLEQRCLRLSAREASEEELGLVHSPEYVSLVRETQVLGKEELQALSGQFDAIYFHPSTFHCARLAAGAGLQLVDAVLTGAVQNGLALVRPPGHHGQRAAANGFCVFNNVAIAAAHAKQKHGLHRILVVDWDVHHGQGIQYLFEDDPSVLYFSWHRYEHGRFWPFLRESDADAVGRGQGLGFTVNLPWNQVGMGNADYVAAFLHLLLPLAFEFDPELVLVSAGFDSAIGDPEGQMQATPECFAHLTQLLQVLAGGRVCAVLEGGYHLESLAESVCMTVQTLLGDPAPPLSGPMAPCQSALESIQSARAAQAPHWKSL 357          

HSP 2 Score: 282.722 bits (722), Expect = 7.916e-81
Identity = 140/355 (39.44%), Postives = 217/355 (61.13%), Query Frame = 2
Query: 1577 ESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINFPIN--KSGIEAIRKTLEYQKPYWKCLKFYEPLVVTYTEISPNQTNP 2635
            E P R     + LR   L  RC +L +R AS++E+GL+HSP YV  +                +F++IY +  ++  A L+ G  L ++D V +   +NG A++RPPGHH +     GFC FNNVAIAA +A  K+   + +IL+VDWDVHHG G Q+ F  + +VLY S HRY++G F+P   +    AVG     GF VN+ WN+  + +++Y++AF+++++P++ EF+P+LV+VSAGFD+A GDP G +  TPECF ++TQ+L  LA G+V   LEGGY+L  +++ +   V +LLG P    ++ P+   +S +E+I+     Q P+WK L+  +   VT   +SP+  +P
Sbjct:   26 ERPERLTAALDRLRQRGLEQRCLRLSAREASEEELGLVHSPEYVSLVRETQVLGKEELQALSGQFDAIYFHPSTFHCARLAAGAGLQLVDAVLTGAVQNGLALVRPPGHHGQRAAANGFCVFNNVAIAAAHAKQKHG--LHRILVVDWDVHHGQGIQYLFEDDPSVLYFSWHRYEHGRFWPFLRESDADAVGRGQGLGFTVNLPWNQVGMGNADYVAAFLHLLLPLAFEFDPELVLVSAGFDSAIGDPEGQMQATPECFAHLTQLLQVLAGGRVCAVLEGGYHLESLAESVCMTVQTLLGDPAPP-LSGPMAPCQSALESIQSARAAQAPHWKSLQQQD---VTAVPMSPSSHSP 374          
BLAST of Histone deacetylase,putative vs. TrEMBL
Match: A0A0X3PKU1 (UBP-type domain-containing protein OS=Schistocephalus solidus OX=70667 GN=TR96205 PE=4 SV=1)

HSP 1 Score: 880.937 bits (2275), Expect = 0.000e+0
Identity = 482/1149 (41.95%), Postives = 671/1149 (58.40%), Query Frame = 2
Query:  179 FGDEDLPAAQSNHGLYDNIELRINFPNKTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKENDQLNHKIYELR---TKNAFNNYPNKTCFVYDCRMENHMNERSIH-PESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLAN------------GKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINFPI--NKSGIEAIRKTLEYQKPYWKCLKFYEPL--------------VVTYTEISPNQTNPAALDNIVQI--DTNTLAESVRQLGIVEVTFQTEQSIEETLSQPRNDTFITE---------PNSSNPIIHLPPIVSSDNAVEVPATTSINSTTH---ATQNISANFLSVDQSSGATPV------SANVSRVINE-------------GNSV----GLVLQDIMNLSGVSNSDIHHFLGLTSNDPLPERVYAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQVFCGRFVQAHMMQHFQNTRHAIVLSFVDLSSWCYECDSYVHNECLNHAKREAHIAKFGVPQPS 3418
            FGDED+    +  G+      RI     TA  +   ML H++     Y E P RL+  +E   +  L + C+ +Q +   +EL+ Y+HSQ ++  +  T TM+    +   ++ DC  F+  T  A+ +S G+    + +V+    +N  CL RPPGHHAM +EA GFC+FNNV IAAK+A       ++LIVDWDVHHG ATQY FYN +KVLY SIHRY+DG FWPKLRESNYD++G   G GYNINIPLN    T++DYL+IF+ +++PIAYE++P+L+L+SAG+D A+GCP G   + P+ FAH+TH+LM LA G+VVV LEGGY  ESL DSV  T+ATL G   P LE            IQNC+  L   WK LS+    N  P  + +  L  ++W     P   +E+     +E      K+ +LR   T  + +N  N+ C VYD RMENH +E   H PE P R +  +E L +  L  RCK+ E+R+A++DE+  +H  +YV+ +    + S    +     F+SIY N+HSY SA+L+ G LL+V+D++C+  + +G A+IRPPGHHAE +   GFCFFNNVA+A  +A   +    K+I +VDWDVHHGNG QH+F  + +VLYIS+HR+D+G FFPGS D + +AVG    EG   N+ WN RPVRD +YI+AF++ V+P+ +EF P+L  ++AGFDAARGD LGG  V+PECFG+MT +LT++A             G +ILALEGGYNL V S+ +SHCV+SLLG  T   +N  I   +    AIR+T+E  + YWK L  Y P+               VT ++ +   T PA   + V    D   L         +  +   E + E TL+   + T   E         P ++   + LP   S+  + E   + ++  + H    T ++     +    S A+ V      SA+ S V  +             G+S+    G  L +++     S  D+  F GL S+D LPER++AV+P+LWC HL  V  S SA   D+N +CT CP+  ENW+CLTCYQV+CGR+   HM++HF  TRH IVLSF DLS+WCY C+SYVHNE L  AKR AH+AKFG   P+
Sbjct:   57 FGDEDIQVVFAGLGINSMFHRRIASSRGTALYFHGDMLKHAHQVHENYPEHPGRLKSIHEKCVDRGLFDRCLTMQPELATDELLRYAHSQEYINEVAATATMSPEAREAYITKFDCAVFNEFTNRAARLSVGALTNAVDSVMRGDVRNAICLTRPPGHHAMNAEACGFCVFNNVEIAAKFAIDRTEANRVLIVDWDVHHGQATQYAFYNDNKVLYFSIHRYDDGAFWPKLRESNYDFVGEGRGYGYNINIPLNGPGYTDNDYLTIFNCLLMPIAYEFDPDLILVSAGYDCALGCPLGCFSLTPSVFAHLTHRLMALADGKVVVTLEGGYNTESLADSVANTVATLLGDPLPSLEAVAPVKPGTVTAIQNCVSMLRTRWKCLSLFPISNAVPLKD-MSDLSTNSWKKVMEPFTGVEEFGLTPEELAIATAKVVDLRQVHTPFSIDN-SNRVCLVYDSRMENHKSETDRHQPECPARIRRAYELLEEYGLARRCKRTEARVATRDELLRVHDADYVDLIEQTSRLSQADLNEAGSVFDSIYFNKHSYDSAVLAVGSLLSVVDDICNCEALHGVAVIRPPGHHAEKDSCAGFCFFNNVALAVRHAQEIHDR--KRIAVVDWDVHHGNGIQHEFEEDPSVLYISMHRFDDGKFFPGSQDAAATAVGTGAGEGKTANLPWNSRPVRDGDYITAFLHFVLPLLYEFRPELTFIAAGFDAARGDHLGGFGVSPECFGHMTHLLTAIATLNPSTDGSGSHRGGLILALEGGYNLAVTSEALSHCVASLLG-DTCLRLNSGIAPTERSCRAIRRTVEVHRKYWKSLFNYSPITCYCDADTLSRWQAAVTSSQTAGVSTQPATEVSTVTFTADAGCLTSQAHADMRLTQSLSIENTSESTLTPTPSWTGGLELVSVGIPVVPETALASVLLPTDASTPPSSEPTQSMNVPESVHEGNETSHVLTTTATATSVSHASTVPRPPEPSASTSHVQRDDEVPSDTAPAAAAGSSMSVPQGSSLNEVVQFVNTSIDDVPAFFGLNSDDRLPERIFAVEPILWCAHLQSV-TSASAWHPDINGTCTSCPNRGENWVCLTCYQVYCGRYASGHMLEHFSATRHPIVLSFADLSAWCYICNSYVHNEVLLEAKRAAHLAKFGERMPT 1199          
BLAST of Histone deacetylase,putative vs. TrEMBL
Match: A0A210QHS9 (Histone deacetylase 6 OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT11824 PE=4 SV=1)

HSP 1 Score: 843.573 bits (2178), Expect = 0.000e+0
Identity = 439/1077 (40.76%), Postives = 630/1077 (58.50%), Query Frame = 2
Query:  254 PNKTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHE---PYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKE-----------------NDQLNHKIYELRTKNAFNNYPNKTCFVYDCRME-NHMNERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINFPINKSGIEAIRKTLEYQKPYWKCLKFYEPLVVTYTEISPNQTNPAALDNIVQIDTNTLAESVRQLGIVEVTFQTEQSIEET----LSQPRNDTFITEPNSSNPIIHLPPIVSSDNAVEVPATTSINSTTHATQNISANFLSVDQSSGATPVSANVSRVINEGNSVGLVLQDIMNLSGVSNSDIHHF-LGLTSNDPLPERVYAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQVFCGRFVQAHMMQHFQNTRHAIVLSFVDLSSWCYECDSYVHNECLNHAKREAHIAKFGV 3406
            P  T  VYD++M     +WD  + E+P+R+   +    E  L+E C RI+A+    + +   H+++H++ +++T  M+   LK++S+++D ++    T  AS ++ GST+E+++ +L  + +NG  +IRPPGHHAM  E  G+C FN V IAAK+A      +++LIVDWDVHHG ATQ  FY+  +VLY SIHRYE G +WP LRES+YD+IG  +G+GYN+N+PLNK +MT++DYL+IFH I++PIA++++P+LVL+S+G+D+AIGCPEG M V P  +AHMTH LM LA GRV + LEGGYC++SL ++V LTL +L G   P L    +P  S+  TI N +K L  +W   S       E   PY E     P+        P +P     NK KE                   + +  I +L    +    PNKTC VYD  M  +H      HPE P R   IF+   +  LL RC +++SRLA+  E   IHS +Y+E +    +  P      +  FNSIY+   S + A ++ G +L+V + V S ++++G A++RPPGHHAE    +GFCFFN+VAIAA YA  K+   +K++LI+DWDVHHGNGTQH F+ + ++L+ISLHR+D+G F+P STDG+ +  G    +GFNVNI +N+ P  D+EY +AF  IVMPI++EF P+LV+VSAGFDAA GDPLGG  +TP  +G+MT ML+SLANG+V+LALEGGYNL+ IS+ M+ C S LLG P   +      +S ++ I  TL+  K +WKCLKF E +     +    +          +     + E  +++  V V  +  QS EE      S+P   T  T  N  +         S       P T+    +   T    +      +  GA   +A+++   +     G  L ++M   G +++ +    +     D   ER+YAVQPL WC HL  VQ  P    +D  A C  C +  ENW+CL CY+VFC R+V  HM+ H    +H + LSF DLS WCY CD+Y+ N+ +N AKR AH  KFG 
Sbjct:   88 PEGTGLVYDDRMATFECLWDPAFPEKPERITESFARCSELGLIERCTRIEAQYGTEDQVLIQHTEAHLEKLKETVDMSKEALKKVSAKYDSIYIHQATYEASLLALGSTMELMEQILKKKVRNGLAIIRPPGHHAMNEEFCGYCFFNQVAIAAKHAVDTLGLKRVLIVDWDVHHGQATQQMFYDDPRVLYFSIHRYEYGKYWPNLRESDYDFIGDGKGKGYNVNVPLNKVHMTDTDYLAIFHQILMPIAHQFSPDLVLVSSGYDAAIGCPEGEMLVSPVTYAHMTHMLMSLAEGRVCICLEGGYCIKSLSEAVALTLRSLLGDPCPALPAMGDPSHSITTTILNVIKVLQPYWNCFSYQTELALEESCPYEEVNDMPPK--------PGMPFVTEENKPKEYTIMYEYEDGVEEEYIIQHKFDAVIDQLIADTSLAVPPNKTCIVYDEGMRVHHAITFRGHPEDPDRVTCIFDKHAEWGLLDRCLRVQSRLATDGETQAIHSSSYLEQMQASAELPPMELRNLQHSFNSIYMCPESNVCARMAAGCVLSVTEAVLSGQAKSGVAVVRPPGHHAECTKAMGFCFFNSVAIAAKYAQNKF--GLKRVLILDWDVHHGNGTQHSFYDDPSILFISLHRFDHGSFYPTSTDGNHNMTGSGAGKGFNVNIPFNEGPKGDAEYKAAFQQIVMPIAYEFAPELVLVSAGFDAALGDPLGGYHITPAGYGHMTHMLSSLANGRVVLALEGGYNLSSISNSMATCTSVLLGDPCPYLPYVQPQESAVKGINNTLDSHKQFWKCLKFRESIPDLRCKEGEGEPEGIEEQKEEEKFKKNIEELSKKMTSVSVYDRAAQSPEEAKSANKSEPEVTTQATSTNDKD---------SGSVGDATPTTSETKPSVTETTPTPSKSSDTMEDQGAVGGAASMAVGGSSVGGAGTPLNEMMGAVGGADNLLQALTVAQALEDMGVERMYAVQPLTWCPHLQTVQPLPQGI-LDTRAPCQDCGNEGENWICLVCYKVFCSRYVNEHMVIHGATEQHLVTLSFSDLSVWCYGCDNYIDNQVVNAAKRAAHRHKFGT 1144          
BLAST of Histone deacetylase,putative vs. TrEMBL
Match: A0A1S3JEN4 (LOW QUALITY PROTEIN: histone deacetylase 6-like OS=Lingula unguis OX=7574 GN=LOC106172630 PE=4 SV=1)

HSP 1 Score: 832.402 bits (2149), Expect = 0.000e+0
Identity = 441/1097 (40.20%), Postives = 631/1097 (57.52%), Query Frame = 2
Query:  263 TAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQ-------------------------------------LKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSL---------SVNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKEND---QLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMNERSI-HPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINFPINKSGIEAIRKTLEYQKPYWKCLKFYEPLVVTYTEISPNQTNPAALDNIVQIDTNTLAESVRQLGIVEVTFQTEQSIEETLSQPRNDTFITEPNSSNPIIHLPPIVSSDNAVEVPATTSINSTTHATQNISANFLSVDQSSGATPVSANVSRVINEGNSVGLVLQDIMNLSGVSNSDIHHFLGLTSNDPLPERVYAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQVFCGRFVQAHMMQHFQNTRHAIVLSFVDLSSWCYECDSYVHNECLNHAKREAHIAKFG 3403
            T  +YD  M  H   WD L+ E PDR+   Y    +  L+  C+ I  K+  +E     HS  +++L++D+Q ++ IQ                                     L++LS ++D ++F++ T   + +S GSTIE+ + +L ++ +NGF ++RPPGHHAM  EA G+C FNNV IAAK A   +  +++LIVDWDVHHG  TQY FY+  +V+Y+SIHRYE GNFWP LRES+YDYIG   G GYNINIPLNKT MTNSDY+++FH +++PI YEYNP+LVL+S+G+D+AIGCPEG M+V PAC+AH  + L  LA G++ V+LEGGYC++SL + V LTL  L G   P++    +P D +K+TI N ++ L  +W+ L         S  V+   +   E+LR +P ST   ++    PI++     +E +     + +I EL         P++T  VYD  M  H N     HPE P R   I+  +++  LL  C ++ESR+A+ +E+   H   + + +  I +  P      + ++NS+Y+ Q SY  ALL+ G LLNV++ V +++S+NG A+IRPPGHHAE+N   GFC FNNVAIAA YA   +   +KK+LI+DWDVHHGNG QH F  + +VLYIS+HRYD G FFP   DG+   VG     GFN+NI WNK  + D+EYI+AF+ ++MP+++EF+PDLV+VSAGFDAARGDPLG   +TP  +G+MTQML SLANG+VILALEGGYNL+ IS+ M+ C   LLG     + +       +E+I   L+  K YWKCL+F   L      ++      A + N     T+ +      +G ++V +++  S  +  S                 +  P + SSD                               +G +P+ A          +  L +++++  +     D+  F  +    PLP          WCEHL  V   P    +DV A+C++C ST+ENW+CLTCY+V CGR+V  HM+ H  +T H +VLS+ DLS WCY CD+Y+HNE +   KR AH +KFG
Sbjct:  127 TGLIYDHFMTQHRCEWDLLHPECPDRITEPYLRCLQYGLVTRCVPILPKKSVDEAALSQHSPEYLKLLKDSQFLSEIQPLQDLSEKYHGIYFNSPKMTSEKGHLPEHFLPRGVQTLQDLSGKYDSIYFNSKTFECAQLSLGSTIEMTEQILQEKVRNGFAIVRPPGHHAMYKEACGYCFFNNVAIAAKRALDKFGLERVLIVDWDVHHGQGTQYMFYDDPRVMYVSIHRYEYGNFWPNLRESDYDYIGEGRGTGYNINIPLNKTGMTNSDYMAVFHQLLMPIFYEYNPQLVLVSSGYDAAIGCPEGEMEVTPACYAHFINMLSALADGKLAVILEGGYCLKSLSEGVALTLRALLGDPTPRIGPLQQPNDVIKKTILNAIRVLRPYWQCLQFQGVLPVQSAEVSSTTQE-DEHLRTVPFST-PENRPEVYPIDECCYPVQEPEVKATYSARIQELIDNTYLGKAPHRTALVYDEVMRKHKNHVDPGHPERPDRITKIYNKIQEYRLLKHCLRVESRMATDEEVLTCHKTEHFKKMQQIKETKPRELKEVQLQYNSVYLCQESYDCALLAVGSLLNVVEAVLTNKSQNGVAVIRPPGHHAEINQACGFCLFNNVAIAARYAQKTF--GVKKVLILDWDVHHGNGIQHIFEDDPSVLYISIHRYDQGFFFPAGPDGNYDKVGNGAGAGFNINIPWNKYGMGDAEYIAAFLQVIMPVAYEFDPDLVLVSAGFDAARGDPLGHCDITPAGYGHMTQMLMSLANGRVILALEGGYNLHSISESMAMCTKVLLGGTCPPLGSLVPKTMAVESICNVLDTHKKYWKCLQFRVDLPAPVLPVT------AGVQNNAVTSTSDMDSLTTAIGALQVKYESVSSSSDGGSF----------------LSSPTVTSSD------------------------------CTGDSPLGA-----CGGSEAKNLTVRELLGGALADQDDLQMFAVV----PLP----------WCEHLKMVAPPPERG-LDVFAACSMCESTKENWVCLTCYEVCCGRYVNEHMLFHGLSTEHKMVLSYSDLSVWCYGCDAYIHNEIIVPHKRAAHRSKFG 1147          

HSP 2 Score: 317.775 bits (813), Expect = 5.272e-87
Identity = 157/371 (42.32%), Postives = 229/371 (61.73%), Query Frame = 2
Query:  221 LYDNIELRINFPNKTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNV 1333
            L DN  L    P++TA VYDE M  H N  D  + ERPDR+   Y  I E  LL+ C+R++++   +E +   H   H + ++  +     +LKE+  Q++ V+    +   + ++ GS + V++AVL ++++NG  +IRPPGHHA  ++A GFC+FNNV IAA+YAQ  +  +K+LI+DWDVHHGN  Q+ F +   VLYISIHRY+ G F+P   + NYD +G   G G+NINIP NK  M +++Y++ F  +I+P+AYE++P+LVL+SAGFD+A G P G  D+ PA + HMT  LM LA GRV++ LEGGY + S+ +S+ +    L G   P L     P     E+I N L     +WK L   V
Sbjct:  579 LIDNTYLG-KAPHRTALVYDEVMRKHKNHVDPGHPERPDRITKIYNKIQEYRLLKHCLRVESRMATDEEVLTCHKTEHFKKMQQIKETKPRELKEVQLQYNSVYLCQESYDCALLAVGSLLNVVEAVLTNKSQNGVAVIRPPGHHAEINQACGFCLFNNVAIAARYAQKTFGVKKVLILDWDVHHGNGIQHIFEDDPSVLYISIHRYDQGFFFPAGPDGNYDKVGNGAGAGFNINIPWNKYGMGDAEYIAAFLQVIMPVAYEFDPDLVLVSAGFDAARGDPLGHCDITPAGYGHMTQMLMSLANGRVILALEGGYNLHSISESMAMCTKVLLGGTCPPLGSL-VPKTMAVESICNVLDTHKKYWKCLQFRV 947          
BLAST of Histone deacetylase,putative vs. TrEMBL
Match: A0A3Q0KMY1 (Histone deacetylase,putative OS=Schistosoma mansoni OX=6183 PE=4 SV=1)

HSP 1 Score: 824.698 bits (2129), Expect = 0.000e+0
Identity = 452/1151 (39.27%), Postives = 670/1151 (58.21%), Query Frame = 2
Query:  179 FGDEDLPAAQS--NHGLYDNIELRINFPNKTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYA--QLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSV-NVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKENDQLNHKIYELRTKN--AFNNYPNKTCFVYDCRMENHMNERS-IHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLA-------------------------------------NGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQI-INFPINKSGIEAIRKTLEYQKPYWKCLKFYEPLVVTYTEISPNQTNPAALDNIVQ-------------------IDTNTLAESVRQLGIVEVTFQTEQSIEETLSQP--RNDTFITEPNSS--NPIIHLPPIVSSDNAVEVPATTSINSTTHATQNISANFLSVDQSSGATPVSANVSRVINEGNSVGLVLQDIMNLSGVSNSDIHHFLGLTSNDPLPERVYAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQVFCGRFVQAHMMQHFQNTRHAIVLSFVDLSSWCYECDSYVHNECLNHAKREAHIAKFGVPQPSNS 3424
              D+D+P   S  ++  +D  + + +    TAF+YDE+MLLH N+W   + E P+R     +      LL  C+ I  +   ++ +   H   +++ I+ T TM   +LK+LS+  D V+F+ +T L++ +S GS I+ +  +     +N FCL+RPPGHHA+ +EA GFCI+NNV IAA YA  +LNY+  +ILIVDWDVHHGN TQY FY+  KVL+ISIHRY++G FWP LRESNYD+IG   GRG+N+NI LN  ++ +SDYL+IFH I+LP+AYE++PELVL+SAG+DS+ GCP G +++ P+ +AH+THKLM  A G+V+V LEGGY +++L +SV  TL+ L G   P L+       SV ETI NC+  L F WK L +  + +++  +P+ + HL   +W+  KVP     D  +  ++   +  +   L+  +  A NN  + TC VYD RM+NH NE    +PE+P R +  +  L+   L  RCK +E+R A++ E+  +H+  YV ++ +      T  + F    NS+Y N H+Y +ALL+ G LL VIDEVCS  S NG A+IRPPGHHA  +  +GFCFFNNVAI A +A   Y   +++I I+DWDVHHGNGT   F  + N+LYIS+HR+D+G +FP S   S    G  +  G  ++IAWN R V+D +YI  F NI++PI +EF P L++VSAGFDAA GD LG L V+PECF ++T +L ++                                      +G ++LALEGGY +  +S C++HCV++LLG    ++  N  I++   +++++T+E    YW  LK ++P+   Y + S  +  P    N  Q                   I+ N  ++ V    +  +    +Q I +  S P   N+  + +  S      + L    S +N  +  ++TSI+      Q +         ++  + V+     VI+   S         N SG ++ DIH F GL S+  L  +V+AV PL WC HL  V  +P+  + D+N+ C  C  + ENW+CL+CY V+CGR+  +HM++HF  T+H+IVLS+ DLS+WCY+C+SYVHNE L + KR  + AKFG   P +S
Sbjct:   22 LSDKDIPVIFSAFDNSRHDYFDKQSSHDKGTAFIYDERMLLHKNIWFPNFLECPERFSATIDKCTTYGLLSRCLIINPEPATDDFLTLYHQTEYIEQIKQTTTMEDNELKQLSATLDSVYFNKHTDLSARLSVGSWIQAVDLIHHGDVRNAFCLVRPPGHHALTNEACGFCIYNNVAIAANYAIEKLNYN--RILIVDWDVHHGNTTQYAFYDNPKVLFISIHRYDNGEFWPNLRESNYDFIGTGRGRGFNVNIALNDKDIGDSDYLTIFHRIVLPLAYEFDPELVLVSAGYDSSFGCPVGQLNLSPSLYAHLTHKLMAFAEGKVIVGLEGGYYLDTLSESVGHTLSALLGDPMPSLDPMKPINPSVLETISNCISTLSFRWKFLHIYPLLNDNVLFPD-ISHLKLQSWSDVKVPNFEPTDEHHNVEDKLGIEKRFDYLKNTHPIAGNNKISGTCLVYDNRMQNHKNEEDPTYPENPERIKHTYALLKQLGLKRRCKCIEARYATRTELLRVHTEEYVNTIASTVNMEQTALNDFGASENSVYFNCHTYDNALLASGSLLAVIDEVCSGESLNGMALIRPPGHHALKDRCMGFCFFNNVAIGARHAQQVY--GLERIAIIDWDVHHGNGTAEIFEDDPNILYISVHRFDHGRYFPNSDFSSSQFCGTGEGLGRTIHIAWNGRDVKDGDYIVTFTNIIIPILYEFRPQLILVSAGFDAAHGDKLGRLGVSPECFAHLTHLLMTVVHLNPSVYTLNHRKNSPIISTPTRQTRQRLQQEKSISYSGGLVLALEGGYQITALSQCVAHCVATLLGDNCPRLSSNLSISEKSCKSMQQTIEIHSNYWNMLKGFDPVNRFYDQDSIRR--PVIGRNTRQNPQNTTTTTISSSSSSNTTIELNNESDLVHS-KLNNLCLNDKQPITKCTSTPGDNNNNHLDDEFSQLFKTKLTLNADSSLNNTSDRLSSTSISKHPSERQYVHEQNSYETLNNSESTVAKTSGVVIDPSESHHQQQPSTSNGSGFTSEDIHDFFGLPSSHELTSQVFAVTPLSWCPHLISVHNNPNW-KPDINSLCNSCNHSNENWVCLSCYSVYCGRYANSHMIEHFNITKHSIVLSYADLSTWCYQCESYVHNEVLLNMKRAVYQAKFGEVMPGSS 1163          
BLAST of Histone deacetylase,putative vs. TrEMBL
Match: A0A158QH17 (UBP-type domain-containing protein OS=Rodentolepis nana OX=102285 GN=HNAJ_LOCUS1265 PE=4 SV=1)

HSP 1 Score: 819.305 bits (2115), Expect = 0.000e+0
Identity = 433/1094 (39.58%), Postives = 633/1094 (57.86%), Query Frame = 2
Query:  179 FGDEDLPAAQSNHGLYDNIELRINFPNKTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKENDQLNHKIYELRTKNAFNNYPN--KTCFVYDCRMENHMNERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANG------KVILALEGGYNLNVISDCMSHCVSSLLGYPTNQI--INFPINKSGIEA-------IRKTLEYQKPYWKCLKFYEPLVVTYTEISPNQTNP-AALDNIVQI----DTNTLAESVRQLGIVEV-TFQTEQSIEETLSQPRNDTFITEPNSSNPIIHLPPIVSSDNA----------VEVPATTSINSTTHATQNISANFLSVDQSSGATPVSANVSRVINEGNSVGL-VLQDIMNLSGVSNSDIHHFLGLTSNDPLPERVYAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQVFCGRFVQAHMMQHFQNTRHAIVLSFVDLSSWCYECDSYVHNE 3358
            FGDED+    +  G+  N + R+N   +TA      ML HSN   +   E PDRLR  ++ + E  LL  C+ IQ   I  EL+ + H+QS++  +  T+ M      +   + DC +F  +T +A+ ++AGS    +  V     +N FCL+RPPGHHAM+ EA G+C+FNNV IAAK+A       +ILIVDWD+HHG  TQY FYN SKVLY SIHRY++G +WP LRES+YD++G  +  GYNIN+PLN  + T+ DYL+IF+ +++PIAYE+ P+LV+ISAG+D A+GCP G   + PA FAH+T +LM LA G+++  LEGGY +E+L D V  T++ L G   P L+         +E I+NC+  L   WK L V   +   P  + L  L  ++W +  VP   ++       E      K+ ELR    F    +  + C VYD RMENH  E+  + E P RT+  +E L +  L  RC++ ++RLA+ DE+  IH+P Y++ L      S      + ++F  +Y+N+H++ SA L+ G LL VID+VC+  S +G A+IRPPGHHAE +  +GFCFFNN+A+A  +A  +   +++KI +VDWD+HHGNG Q  F  + +VL+IS+HR+D G F   S+D S   VG  + EG N+NI WN R +RD ++I+AF +IV+P  +EF PDLVIV+AGFD  RGD LGG++V+ ECFG++T  L   A+        ++LALEGGYN+NV S+ +SHCV+SLL  P  ++     P    GI         + +T     P+            + T  S   T P  A  N+  I     T+  AES   L  V + T+  E +         N +F         +I L P  + +            +  PA+ S+ ++T  +Q   +  +S    +   PV    S   +  + + L  ++ ++  S V   D++ FLGL S DP+P+R++AV+P LWC HL+ V +S      D+N  C+ C + +ENW+CLTCY+V+CGR+ Q HM+QH+  ++H IVLS  DLS+WCY C+ Y+HNE
Sbjct:   22 FGDEDVQVVFAGLGISSNFQRRLNSSRRTALFCHNDMLKHSNPLHDDCPECPDRLRSTFQKLIEYELLRRCLLIQPSAIGTELLRFIHAQSYIDAVASTEEMADSARHQFMQKFDCAYFSKDTNIAARLAAGSLTHAVDIVTRGDVRNAFCLVRPPGHHAMKDEACGYCVFNNVAIAAKHALTQLVANRILIVDWDIHHGQGTQYAFYNDSKVLYFSIHRYDNGEYWPSLRESDYDFVGQGQSYGYNINVPLNGKDYTDIDYLTIFNVLLMPIAYEFGPDLVIISAGYDCALGCPYGGFILSPAVFAHLTSRLMALADGKLICALEGGYGLETLSDCVAHTVSALLGDPLPTLDPLKPLHPGTREAIRNCVSVLRAKWKCLGVFPINQSLPLKD-LSSLALNSWKTVMVPSTAVDPFERSESELSADKAKLEELRKSYRFTALTDLERVCLVYDSRMENHKPEQERYLECPNRTRRAYELLEEYGLARRCRRTDARLATDDELLRIHTPEYIDELKKTASMSQNEIDEYAKQFQWVYMNKHTFDSASLAGGSLLAVIDDVCNGESLHGVAVIRPPGHHAERDCCMGFCFFNNIALAVRHA--QEVHNLQKIAVVDWDIHHGNGIQRIFDDDPSVLFISIHRFDGGQFLQNSSDASADHVGVGEGEGTNINIPWNGRNLRDGDFIAAFFHIVLPTLYEFRPDLVIVAAGFDVVRGDHLGGVSVSVECFGHLTHHLMGAASALSSRRCGLVLALEGGYNINVTSEALSHCVASLLSDPCVRLPGSQVPTENHGIFLSGPLNCHLDQTTVSTNPFITTNSTITVGNTSTTRASSETTIPLTATPNVTTIASFESTDFSAESSFLLHTVSISTYPMETT---------NASFTATDYQQEEVITLSPTPAHNEEHFLLLTKLFNLAYPASQSLLTSTQPSQPQPS--VSTLTPTADAPVPGP-STAHSSSSQISLDAMRQLVEFSDVGIEDLNTFLGLNSTDPVPDRLFAVEPSLWCPHLDLV-ESAGQWRPDINRPCSRCDNRQENWVCLTCYEVYCGRYAQGHMLQHYNTSQHPIVLSLADLSAWCYVCNGYIHNE 1099          

HSP 2 Score: 332.798 bits (852), Expect = 2.183e-90
Identity = 173/423 (40.90%), Postives = 248/423 (58.63%), Query Frame = 2
Query:  248 NFPNKTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIA-----------------AKYAQLNYST-----------QKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNP 1432
             F   T   +DE+M  H + W     E P+R+    + + +  L+  C R+ A+   +E +   HS+ +++L++ +  M   +L  LS  +D VFF+++T  AS ++AGS  E+   + + +  NG  L+RPPGHHAM  EA G+CIF NV IA                 +K   L  +T           ++ILI+DWDVH G  TQY FYN ++VL+IS+HRYE   FWP LRE +YD+IG   GRG+NINIPLNKT MT+ DYL+IF+S+I+PIAYE+NPE+V +S+GFD+A+G PEG M + PAC+ HMTH+L  LA G++VV+LEGGY +ESL++  V  L  L G     L+    P  S++ TI + +  L  FW+ L +         P+  R  P ++W   K    P E NP
Sbjct: 1119 KFGKGTGICFDERMEQHRHEWFLDEQECPERVARPLKLMEDQGLISRCTRVPARHATDEELLKVHSKDYIELVKSSAKMGKDELYSLSGNYDGVFFNSHTWEASSLAAGSVTELASQIANGKVANGLALVRPPGHHAMYDEACGYCIFGNVSIAVASLLDSLPLSLYNPIPSKVRPLTSTTSPKNSLRSPRFKRILIIDWDVHQGQGTQYNFYNDNRVLFISMHRYECQKFWPMLREGDYDFIGDGIGRGFNINIPLNKTGMTDGDYLAIFYSLIMPIAYEFNPEIVFVSSGFDAAVGDPEGKMWISPACYGHMTHQLRTLADGKLVVVLEGGYFIESLEEGCVQVLKALLGDYIAPLQNLSPPSKSIRCTISSSIIALREFWQCLGLVELSLCSTRPDISR-FPPNSWPLVKKVVWP-EKNP 1539          

HSP 3 Score: 249.98 bits (637), Expect = 1.353e-63
Identity = 133/421 (31.59%), Postives = 223/421 (52.97%), Query Frame = 2
Query: 1475 ELRTKNAFNNYPNKTCF-----------VYDCRMENHMNERSI-HPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKY--------------------------SESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINF-PINKSGIEAIRKTLEYQKPYWKCLKFYE-PLVVTYTEIS 2617
            E++ K    + P  +C             +D RME H +E  +   E P R     + + D  L+SRC ++ +R A+ +E+  +HS +Y+E + +  +      +     ++ ++ N H++ ++ L+ G +  +  ++ + +  NG A++RPPGHHA  +   G+C F NV+IA    L                             S   K+ILI+DWDVH G GTQ+ F+ +  VL+IS+HRY+   F+P   +G    +G     GFN+NI  NK  + D +Y++ F +++MPI++EFNP++V VS+GFDAA GDP G + ++P C+G+MT  L +LA+GK+++ LEGGY +  + +     + +LLG     + N  P +KS    I  ++   + +W+CL   E  L  T  +IS
Sbjct: 1099 EMKAKPQTTSAPQTSCLDEAKFGKGTGICFDERMEQHRHEWFLDEQECPERVARPLKLMEDQGLISRCTRVPARHATDEELLKVHSKDYIELVKSSAKMGKDELYSLSGNYDGVFFNSHTWEASSLAAGSVTELASQIANGKVANGLALVRPPGHHAMYDEACGYCIFGNVSIAVASLLDSLPLSLYNPIPSKVRPLTSTTSPKNSLRSPRFKRILIIDWDVHQGQGTQYNFYNDNRVLFISMHRYECQKFWPMLREGDYDFIGDGIGRGFNINIPLNKTGMTDGDYLAIFYSLIMPIAYEFNPEIVFVSSGFDAAVGDPEGKMWISPACYGHMTHQLRTLADGKLVVVLEGGYFIESLEEGCVQVLKALLGDYIAPLQNLSPPSKSIRCTISSSIIALREFWQCLGLVELSLCSTRPDIS 1519          
BLAST of Histone deacetylase,putative vs. Ensembl Cavefish
Match: hdac6 (histone deacetylase 6 [Source:ZFIN;Acc:ZDB-GENE-030131-3232])

HSP 1 Score: 734.561 bits (1895), Expect = 0.000e+0
Identity = 411/1084 (37.92%), Postives = 587/1084 (54.15%), Query Frame = 2
Query:  230 NIELRIN-FPNKTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGS-MDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSV---NVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKENDQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMNE-RSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLG-YPTNQIINFPINKSGIEAIRKTLEYQKPYWKCLKFYEPLVVTYTEISP-----------NQTNPAALDNIVQIDTNTLAESVRQLGIVEVTFQTEQSIEETLSQPRNDTFITEPNSSNPIIHLPPIVSSDNAVEVPATTSINSTTHATQNISANFLSVDQSSGATPVSANVSRVIN------EGNSVGLVLQDIMNLSGVSNSDIHHFLGLTSN--DPLPERVYAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQVFCGRFVQAHMMQHFQNTRHAIVLSFVDLSSWCYECDSYVHNECLNHAKREAHIAKFG 3403
            NI+LR       T  VY E    H  +WD  + E P+R+    E + +  LL  C++++ +    E I   H++ ++  +  TQ MT  ++K +S  +D V+   +T   + ++ GS ++++  V+    +NGF + RPPGHHA     +G+C+FNN+ +AA+YAQ  +  Q++LIVDWDVHHG   QY F +   VLY S+HRYEDG+FWP L ES+   +G+  G GYNIN+P NKT M + DY++ F  ++LP+AYE+ P+LVL++AGFDS +G P+G  M   P CF+ +TH LM LA+GR+V+ LEGGY +++  +    +L +L G   P L     P +S   +I   +  L+ FW SL +         EP P            SS   ++ +E +                LR+          T  VYD RM  H N   S HPE P+R   IF    +   + RC+++ +RLA+++E+ L H   ++ ++ +  Q  P   H   +E+NSIYI+Q SY SALL+ G   N    + + +  NG AI+RPPGHHAE +   GFCFFN  A+ A YA +  + S  ++LI+DWDVHHGNGTQH F  + +VLYISLHRY++GLFFP S D +   VG     G+NVNI WNK  + D EY++AF NIVMPI+ EF P+LV+VSAGFDAARGDPLG   VTPE + ++T  L SLA G+V++ LEGGYNLN IS+ M+ C S LLG  P       P + S    I   L    PYW+ L+   P  +  +  SP           ++ +P              +  V          Q +  ++E L+Q  +   ++   S+N      P+  +   V+      + S       +  + + V +S  A P+    S  I       E ++V +  QD   L G           L     D   + +Y V PL WC HL  V+  P    IDV   C  C +  ENW+CL CY+V CGRFV+ HM+ H Q + H +VLSF DLS WCY C+SYVHN+ L+  K  AH+AKFG
Sbjct:   65 NIDLRCKPKATGTGLVYSEAFTHHRCLWDTSHPECPERVIAVVELMKKEGLLSRCVQVETRAASEEEISLVHTKEYIDRMRSTQKMTEEEMKLVSDGYDSVYLHPDTFSCACLAVGSVLQLVDKVMTSELRNGFSVSRPPGHHAQTELMNGYCMFNNLAVAARYAQKQHGVQRVLIVDWDVHHGQGIQYIFQDDPNVLYFSVHRYEDGSFWPHLPESDSSAVGSGLGEGYNINLPWNKTGMQDGDYVAAFQRLLLPVAYEFQPQLVLVAAGFDSVVGDPQGGEMSASPQCFSVLTHMLMGLAQGRIVLALEGGYNLQATAEGACASLRSLLGDPCPHLPCPGSPSESALNSISKTVSDLYPFWTSLQILEGGALSEAEPLP------------SSVCAEMNLESS----------------LRS----------TGLVYDQRMMEHHNMWDSDHPERPQRIFRIFSRHEELGFVDRCQRIPARLATEEELALCHGLEHIATIKSTEQMKPRDLHRLGDEYNSIYISQESYKSALLAAGSCFNSAQAILTGQVRNGVAIVRPPGHHAERDKACGFCFFNTAALTARYAQS-ITHSALRVLILDWDVHHGNGTQHIFEEDDSVLYISLHRYEDGLFFPSSEDANYDKVGQGKGAGYNVNIPWNKATMGDPEYLAAFHNIVMPIAREFAPELVLVSAGFDAARGDPLGRYQVTPEGYAHLTHQLLSLAAGRVLVILEGGYNLNSISESMAMCTSMLLGDAPPMLPDLPPPHASAAVTINNVLRAHAPYWRSLRIQIPESLRMSLPSPQPKTKRSSTGRSKKSPRQFTPAQSPSQQQQSSPVITSPASPAAAQEDSGLDE-LTQGLHSLDLSSSTSANSSPTSIPVGGARPKVKPSPQKDVTSA------LEESPVKVIESDRAEPIVKAESTPIKEEKQPAEADAVAMGDQDSGVLEGACGFTQKSVFELVCGAVDMGGDTMYVVDPLAWCPHLESVRPLPVGG-IDVFRPCEECGADSENWVCLCCYKVLCGRFVKEHMVTHGQVSGHPMVLSFADLSVWCYPCESYVHNKVLHEIKNAAHVAKFG 1101          
BLAST of Histone deacetylase,putative vs. Ensembl Cavefish
Match: hdac6 (histone deacetylase 6 [Source:ZFIN;Acc:ZDB-GENE-030131-3232])

HSP 1 Score: 716.072 bits (1847), Expect = 0.000e+0
Identity = 404/1049 (38.51%), Postives = 576/1049 (54.91%), Query Frame = 2
Query:  326 ERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSV---NVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKENDQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMNE-RSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLG-YPTNQIINFPINKSGIEAIRKTLEYQKPYWKCLKFYEPLVVTYTEISPNQTNPAALDNIVQIDTNTLAESVRQL----------------GIVEVTFQTEQSIEETLSQPRNDTFITEP-NSSNPIIHLPPIVSSDNAVEVPATTSINSTTHATQNISANFLSV-DQSSGATPVSANVSRVINEGNSVGLVLQDIMNLSGVSNSDIHHFLGLTSNDPLPERVYAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQVFCGRFVQAHMMQHFQNTRHAIVLSFVDLSSWCYECDSYVHNECLNHAKREAHIAKFG 3403
            E P+R+    E + +  LL  C++++ +    E I   H++ ++  +  TQ MT  ++K +S  +D V+   +T   + ++ GS ++++  V+    +NGF + RPPGHHA     +G+C+FNN+ +AA+YAQ  +  Q++LIVDWDVHHG   QY F +   VLY S+HRYEDG+FWP L ES+   +G+  G GYNIN+P NKT M + DY++ F  ++LP+AYE+ P+LVL++AGFDS +G P+G M   P CF+ +TH LM LA+GR+V+ LEGGY +++  +    +L +L G   P L     P +S   +I   +  L+ FW SL +         EP P            SS   ++ +E +                LR+          T  VYD RM  H N   S HPE P+R   IF    +   + RC+++ +RLA+++E+ L H   ++ ++ +  Q  P   H   +E+NSIYI+Q SY SALL+ G   N    + + +  NG AI+RPPGHHAE +   GFCFFN  A+ A YA +  + S  ++LI+DWDVHHGNGTQH F  + +VLYISLHRY++GLFFP S D +   VG     G+NVNI WNK  + D EY++AF NIVMPI+ EF P+LV+VSAGFDAARGDPLG   VTPE + ++T  L SLA G+V++ LEGGYNLN IS+ M+ C S LLG  P       P + S    I   L    PYW+ L+   P  +  +  SP      +        T    +S RQ                 G+ E+T Q   S++ + S   N +  + P   + P +   P     +A+E      I S    ++   A+ +++ DQ SG           + EG + G   + +  L  V  +D                +Y V PL WC HL  V+  P    IDV   C  C +  ENW+CL CY+V CGRFV+ HM+ H Q + H +VLSF DLS WCY C+SYVHN+ L+  K  AH+AKFG
Sbjct:   86 ECPERVIAVVELMKKEGLLSRCVQVETRAASEEEISLVHTKEYIDRMRSTQKMTEEEMKLVSDGYDSVYLHPDTFSCACLAVGSVLQLVDKVMTSELRNGFSVSRPPGHHAQTELMNGYCMFNNLAVAARYAQKQHGVQRVLIVDWDVHHGQGIQYIFQDDPNVLYFSVHRYEDGSFWPHLPESDSSAVGSGLGEGYNINLPWNKTGMQDGDYVAAFQRLLLPVAYEFQPQLVLVAAGFDSVVGDPQG-MSASPQCFSVLTHMLMGLAQGRIVLALEGGYNLQATAEGACASLRSLLGDPCPHLPCPGSPSESALNSISKTVSDLYPFWTSLQILEGGALSEAEPLP------------SSVCAEMNLESS----------------LRS----------TGLVYDQRMMEHHNMWDSDHPERPQRIFRIFSRHEELGFVDRCQRIPARLATEEELALCHGLEHIATIKSTEQMKPRDLHRLGDEYNSIYISQESYKSALLAAGSCFNSAQAILTGQVRNGVAIVRPPGHHAERDKACGFCFFNTAALTARYAQS-ITHSALRVLILDWDVHHGNGTQHIFEEDDSVLYISLHRYEDGLFFPSSEDANYDKVGQGKGAGYNVNIPWNKATMGDPEYLAAFHNIVMPIAREFAPELVLVSAGFDAARGDPLGRYQVTPEGYAHLTHQLLSLAAGRVLVILEGGYNLNSISESMAMCTSMLLGDAPPMLPDLPPPHASAAVTINNVLRAHAPYWRSLRIQIPESLRMSLPSPQPKTKRS-------STGRSKKSPRQFTPAQSPSQQQQSSPDSGLDELT-QGLHSLDLSSSTSANSSPTSIPVGGARPKVKPSPQKDVTSALEESPVKVIESDRSFSEPAEADAVAMGDQDSG-----------VLEG-ACGFTQKSVFEL--VCGADT---------------MYVVDPLAWCPHLESVRPLPVGG-IDVFRPCEECGADSENWVCLCCYKVLCGRFVKEHMVTHGQVSGHPMVLSFADLSVWCYPCESYVHNKVLHEIKNAAHVAKFG 1056          

HSP 2 Score: 315.464 bits (807), Expect = 3.349e-90
Identity = 158/389 (40.62%), Postives = 234/389 (60.15%), Query Frame = 2
Query:  263 TAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQ-LNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHE-----PYPEYLRHLPESTWNSSKVPK 1411
            T  VYD++M+ H NMWD+ + ERP R+   +    E   ++ C RI A+    E +   H   H+  I+ T+ M    L  L  +++ ++    +  ++ ++AGS     +A+L  + +NG  ++RPPGHHA   +A GFC FN   + A+YAQ + +S  ++LI+DWDVHHGN TQ+ F     VLYIS+HRYEDG F+P   ++NYD +G  +G GYN+NIP NK  M + +YL+ FH+I++PIA E+ PELVL+SAGFD+A G P G   V P  +AH+TH+L+ LA GRV+V+LEGGY + S+ +S+ +  + L G APP L     P  S   TI N L+    +W+SL + + ++       P P+  R    ST  S K P+
Sbjct:  447 TGLVYDQRMMEHHNMWDSDHPERPQRIFRIFSRHEELGFVDRCQRIPARLATEEELALCHGLEHIATIKSTEQMKPRDLHRLGDEYNSIYISQESYKSALLAAGSCFNSAQAILTGQVRNGVAIVRPPGHHAERDKACGFCFFNTAALTARYAQSITHSALRVLILDWDVHHGNGTQHIFEEDDSVLYISLHRYEDGLFFPSSEDANYDKVGQGKGAGYNVNIPWNKATMGDPEYLAAFHNIVMPIAREFAPELVLVSAGFDAARGDPLGRYQVTPEGYAHLTHQLLSLAAGRVLVILEGGYNLNSISESMAMCTSMLLGDAPPMLPDLPPPHASAAVTINNVLRAHAPYWRSLRIQIPESLRMSLPSPQPKTKR---SSTGRSKKSPR 832          

HSP 3 Score: 296.975 bits (759), Expect = 9.161e-84
Identity = 137/352 (38.92%), Postives = 224/352 (63.64%), Query Frame = 2
Query: 1571 HPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQI-INFPINKSGIEAIRKTLEYQKPYWKCLKFYEPLVVTYTEISPN 2623
            HPE P R   + E ++   LLSRC Q+E+R AS++EI L+H+  Y++ + +  + +     L  + ++S+Y++  ++  A L+ G +L ++D+V +    NGF++ RPPGHHA+     G+C FNN+A+AA YA  ++   ++++LIVDWDVHHG G Q+ F  + NVLY S+HRY++G F+P   +   SAVG    EG+N+N+ WNK  ++D +Y++AF  +++P+++EF P LV+V+AGFD+  GDP  G++ +P+CF  +T ML  LA G+++LALEGGYNL   ++     + SLLG P   +      ++S + +I KT+    P+W  L+  E   ++  E  P+
Sbjct:   84 HPECPERVIAVVELMKKEGLLSRCVQVETRAASEEEISLVHTKEYIDRMRSTQKMTEEEMKLVSDGYDSVYLHPDTFSCACLAVGSVLQLVDKVMTSELRNGFSVSRPPGHHAQTELMNGYCMFNNLAVAARYAQKQHG--VQRVLIVDWDVHHGQGIQYIFQDDPNVLYFSVHRYEDGSFWPHLPESDSSAVGSGLGEGYNINLPWNKTGMQDGDYVAAFQRLLLPVAYEFQPQLVLVAAGFDSVVGDPQ-GMSASPQCFSVLTHMLMGLAQGRIVLALEGGYNLQATAEGACASLRSLLGDPCPHLPCPGSPSESALNSISKTVSDLYPFWTSLQILEGGALSEAEPLPS 432          
BLAST of Histone deacetylase,putative vs. Ensembl Cavefish
Match: hdac10 (histone deacetylase 10 [Source:NCBI gene;Acc:103023019])

HSP 1 Score: 333.569 bits (854), Expect = 1.878e-100
Identity = 157/355 (44.23%), Postives = 224/355 (63.10%), Query Frame = 2
Query:  263 TAFVYDEQMLLHSNMWDN--LYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSL 1321
            TA +YDE+M  +  +WD+     E P+RL   YE +    L + C+ +  +E   E I   HS+ +++ ++ T +M+  +LK  + Q   V+F  N    + ++ G++++++ +V+  + +NG  L+RPPGHH+  S A+GFC+FNNV IAA YA+ +Y+  ++LIVDWDVHHG   QY F     VLY S HRYE  +FWP L ES+Y+ +G  +G G+NIN+P NK  MTNSDYLS+F  ++LP AYE++PELVL+SAGFDSAIG PEG M   P  F H+TH LM LA+G++ V+LEGGY + SL  SV  T+ TL G   P L     PC S  E++ N       +W  L
Sbjct:    4 TALIYDEEMSRYQLLWDDPVCAIEVPERLTRSYEAVKSAGLEKRCVPVSVREGTEEEILLYHSKEYLEQVKQTPSMSVEELKTFTQQFGDVYFHPNIYNCAKLAIGASLQLVDSVMKGKVRNGMALVRPPGHHSQRSAANGFCVFNNVAIAALYAKKHYNLNRVLIVDWDVHHGQGVQYCFEEDPSVLYFSWHRYEHKSFWPNLDESDYNTVGKGKGTGFNINVPWNKVGMTNSDYLSVFFHVLLPAAYEFDPELVLVSAGFDSAIGDPEGHMCATPEIFGHLTHLLMSLAKGKLCVVLEGGYNLTSLTQSVCQTMHTLLGDPTPLLSGIGSPCHSALESVVNVRAVHRKYWNFL 358          

HSP 2 Score: 266.544 bits (680), Expect = 2.093e-76
Identity = 137/360 (38.06%), Postives = 210/360 (58.33%), Query Frame = 2
Query: 1517 TCFVYDCRMENHM---NERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQI--INFPINKSGIEAIRKTLEYQKPYWKCLKF 2581
            T  +YD  M  +    ++     E P R    +E ++   L  RC  +  R  +++EI L HS  Y+E +      S      F ++F  +Y + + Y  A L+ G  L ++D V   +  NG A++RPPGHH++ +   GFC FNNVAIAA YA   Y+  + ++LIVDWDVHHG G Q+ F  + +VLY S HRY++  F+P   +   + VG     GFN+N+ WNK  + +S+Y+S F ++++P ++EF+P+LV+VSAGFD+A GDP G +  TPE FG++T +L SLA GK+ + LEGGYNL  ++  +   + +LLG PT  +  I  P + S +E++       + YW  LK+
Sbjct:    4 TALIYDEEMSRYQLLWDDPVCAIEVPERLTRSYEAVKSAGLEKRCVPVSVREGTEEEILLYHSKEYLEQVKQTPSMSVEELKTFTQQFGDVYFHPNIYNCAKLAIGASLQLVDSVMKGKVRNGMALVRPPGHHSQRSAANGFCVFNNVAIAALYAKKHYN--LNRVLIVDWDVHHGQGVQYCFEEDPSVLYFSWHRYEHKSFWPNLDESDYNTVGKGKGTGFNINVPWNKVGMTNSDYLSVFFHVLLPAAYEFDPELVLVSAGFDSAIGDPEGHMCATPEIFGHLTHLLMSLAKGKLCVVLEGGYNLTSLTQSVCQTMHTLLGDPTPLLSGIGSPCH-SALESVVNVRAVHRKYWNFLKY 360          
BLAST of Histone deacetylase,putative vs. Ensembl Cavefish
Match: hdac10 (histone deacetylase 10 [Source:NCBI gene;Acc:103023019])

HSP 1 Score: 333.183 bits (853), Expect = 8.136e-100
Identity = 157/355 (44.23%), Postives = 224/355 (63.10%), Query Frame = 2
Query:  263 TAFVYDEQMLLHSNMWDN--LYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSL 1321
            TA +YDE+M  +  +WD+     E P+RL   YE +    L + C+ +  +E   E I   HS+ +++ ++ T +M+  +LK  + Q   V+F  N    + ++ G++++++ +V+  + +NG  L+RPPGHH+  S A+GFC+FNNV IAA YA+ +Y+  ++LIVDWDVHHG   QY F     VLY S HRYE  +FWP L ES+Y+ +G  +G G+NIN+P NK  MTNSDYLS+F  ++LP AYE++PELVL+SAGFDSAIG PEG M   P  F H+TH LM LA+G++ V+LEGGY + SL  SV  T+ TL G   P L     PC S  E++ N       +W  L
Sbjct:    4 TALIYDEEMSRYQLLWDDPVCAIEVPERLTRSYEAVKSAGLEKRCVPVSVREGTEEEILLYHSKEYLEQVKQTPSMSVEELKTFTQQFGDVYFHPNIYNCAKLAIGASLQLVDSVMKGKVRNGMALVRPPGHHSQRSAANGFCVFNNVAIAALYAKKHYNLNRVLIVDWDVHHGQGVQYCFEEDPSVLYFSWHRYEHKSFWPNLDESDYNTVGKGKGTGFNINVPWNKVGMTNSDYLSVFFHVLLPAAYEFDPELVLVSAGFDSAIGDPEGHMCATPEIFGHLTHLLMSLAKGKLCVVLEGGYNLTSLTQSVCQTMHTLLGDPTPLLSGIGSPCHSALESVVNVRAVHRKYWNFL 358          

HSP 2 Score: 265.774 bits (678), Expect = 1.230e-75
Identity = 137/360 (38.06%), Postives = 210/360 (58.33%), Query Frame = 2
Query: 1517 TCFVYDCRMENHM---NERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQI--INFPINKSGIEAIRKTLEYQKPYWKCLKF 2581
            T  +YD  M  +    ++     E P R    +E ++   L  RC  +  R  +++EI L HS  Y+E +      S      F ++F  +Y + + Y  A L+ G  L ++D V   +  NG A++RPPGHH++ +   GFC FNNVAIAA YA   Y+  + ++LIVDWDVHHG G Q+ F  + +VLY S HRY++  F+P   +   + VG     GFN+N+ WNK  + +S+Y+S F ++++P ++EF+P+LV+VSAGFD+A GDP G +  TPE FG++T +L SLA GK+ + LEGGYNL  ++  +   + +LLG PT  +  I  P + S +E++       + YW  LK+
Sbjct:    4 TALIYDEEMSRYQLLWDDPVCAIEVPERLTRSYEAVKSAGLEKRCVPVSVREGTEEEILLYHSKEYLEQVKQTPSMSVEELKTFTQQFGDVYFHPNIYNCAKLAIGASLQLVDSVMKGKVRNGMALVRPPGHHSQRSAANGFCVFNNVAIAALYAKKHYN--LNRVLIVDWDVHHGQGVQYCFEEDPSVLYFSWHRYEHKSFWPNLDESDYNTVGKGKGTGFNINVPWNKVGMTNSDYLSVFFHVLLPAAYEFDPELVLVSAGFDSAIGDPEGHMCATPEIFGHLTHLLMSLAKGKLCVVLEGGYNLTSLTQSVCQTMHTLLGDPTPLLSGIGSPCH-SALESVVNVRAVHRKYWNFLKY 360          

HSP 3 Score: 55.0694 bits (131), Expect = 4.679e-7
Identity = 38/136 (27.94%), Postives = 63/136 (46.32%), Query Frame = 2
Query:  914 YNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSL 1321
            Y++ + L+K   + +  +     ++LP+AYE++P+LVL      S +  P          +A ++  L  LA+GR + LL+G       KD V  T ++L+G   P L     P D   E I+   + L   W  L
Sbjct:  548 YHVPVCLSKAGHSRASVMQALIGLLLPLAYEFSPDLVLQVLTSSSGLEMP---------VWAQVSSLLQGLAQGRTLALLQG-----CDKDMVGATCSSLSGSPAPILGPLGHPVDKDVEFIEKQRQRLEKKWGLL 669          
BLAST of Histone deacetylase,putative vs. Ensembl Cavefish
Match: hdac7a (histone deacetylase 7a [Source:ZFIN;Acc:ZDB-GENE-150129-1])

HSP 1 Score: 305.449 bits (781), Expect = 7.779e-88
Identity = 162/379 (42.74%), Postives = 231/379 (60.95%), Query Frame = 2
Query: 1517 TCFVYDCRMENHM---NERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEF-------------NSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWN---KRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARG--DPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLG----YPTNQIINFPINKSGIEAIRKTLEYQKPYWKCLK 2578
            T  VYD +M  H     + S HPE   R Q I+  L++  L  +C+ +  R A+ +E+  +    Y++S+  IC   P    L +  F             ++I+   H+  ++ ++ G +  +   V     +NGFA++RPPGHHA+ + P+GFCFFN+VAIAA     K S  + KILIVDWDVHHGNGTQ  F+ + +VLYISLHRYDNG FFPGS  G P+ VG    EGFNVN+AW    + P+ D+EY++AF  +VMPI+ EF+PD+V+VS+GFDAA G   PLGG  VT +CFG +T+ L  LA G+V+LALEGG++L  I D    CVS+LLG    +P   ++  P N + + ++++ L+ Q  YW  +K
Sbjct:  483 TGLVYDSQMLKHQCTCGDNSTHPEHAGRIQSIWSRLQERGLRVQCESIRGRKATLEELSSV----YIKSV--ICVTLPPTGILSQRMFVMLPCGGVGVIDHDTIWNEMHTSTASRMAAGSVTELAFRVAKGELKNGFAVVRPPGHHADPSNPMGFCFFNSVAIAAKQLQQKLS--VTKILIVDWDVHHGNGTQEIFYNDPSVLYISLHRYDNGNFFPGS--GGPTEVGSGAGEGFNVNVAWTGGLEPPMGDAEYLAAFRTVVMPIAREFSPDVVLVSSGFDAAEGHPAPLGGYKVTAKCFGFLTRQLMVLAGGRVVLALEGGHDLTAICDASEACVSALLGVEDPFPEEVLLQKP-NDNAVLSLQRVLQIQSQYWSSVK 850          

HSP 2 Score: 234.572 bits (597), Expect = 1.562e-63
Identity = 136/374 (36.36%), Postives = 205/374 (54.81%), Query Frame = 2
Query:  263 TAFVYDEQMLLHS-NMWDN-LYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQL-IEDTQTMTAIQLKELSS------QHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLN---KTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIG--CPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEK--FDEPCDSVKETIQNCLKFLHFFWKSLSVNVA 1336
            T  VYD QML H     DN  + E   R++  +  + E  L   C  I+ ++   E +   + +S + + +  T  ++      L         HD ++ + +T  AS ++AGS  E+   V     KNGF ++RPPGHHA  S   GFC FN+V IAAK  Q   S  KILIVDWDVHHGN TQ  FYN   VLYIS+HRY++GNF+P         +G+  G G+N+N+      +  M +++YL+ F ++++PIA E++P++VL+S+GFD+A G   P G   V   CF  +T +LM LA GRVV+ LEGG+ + ++ D+    ++ L G   P  E+    +P D+   ++Q  L+    +W S+   V 
Sbjct:  483 TGLVYDSQMLKHQCTCGDNSTHPEHAGRIQSIWSRLQERGLRVQCESIRGRKATLEELSSVYIKSVICVTLPPTGILSQRMFVMLPCGGVGVIDHDTIWNEMHTSTASRMAAGSVTELAFRVAKGELKNGFAVVRPPGHHADPSNPMGFCFFNSVAIAAKQLQQKLSVTKILIVDWDVHHGNGTQEIFYNDPSVLYISLHRYDNGNFFPG--SGGPTEVGSGAGEGFNVNVAWTGGLEPPMGDAEYLAAFRTVVMPIAREFSPDVVLVSSGFDAAEGHPAPLGGYKVTAKCFGFLTRQLMVLAGGRVVLALEGGHDLTAICDASEACVSALLGVEDPFPEEVLLQKPNDNAVLSLQRVLQIQSQYWSSVKAMVG 854          
BLAST of Histone deacetylase,putative vs. Ensembl Sea Lamprey
Match: hdac6 (histone deacetylase 6 [Source:ZFIN;Acc:ZDB-GENE-030131-3232])

HSP 1 Score: 586.26 bits (1510), Expect = 0.000e+0
Identity = 308/781 (39.44%), Postives = 447/781 (57.23%), Query Frame = 2
Query:  263 TAFVYDEQMLLHSNMWDNLYFERPDRLRVCYE--GICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEP-CDSVKETIQNCLKFLHFFWKSLSVNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKENDQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMNE-RSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINFPINKSGIEAI-RKTLEYQKPYWKCLKFYEP 2590
            T  V+D +M L S  W+  +   P  LR   E   +   NL   C+  + +    E + + HSQ ++++++ T  M+  + K LS   D V+    +   + ++ GS +++++ VL    +NGF L+RPPGHHA    A+G+CIFNNV IAA+YA   +  Q++LIVDWDVHHG   QY F +  +VLY S+HR+E G FWP L E +   +G    +G+NIN+P ++T M+++DY++ F  I++P+AY+++P+LVL+SAG+D+A+G P+G M V P CF  +TH LM LA GR+ + LEGGY +E     V  TL  L G          +  C    E I +  K L    KS SV+  D+ E                 K  +   E +P    E   +     E R           T  VYD RM +H N     HPE P R  ++F    D  L+ RC  + +RLA+++E+   HS  +V ++           H    ++NS+Y++  S+ SA L+ G  L++++     +  NG AIIRPPGHHAE +   GFC FN VA+AA +A +     I+ +LIVDWDVHHGNGTQH F  + +VLY+SLHRYD G FFP S D +   VG    +GFNVN+ W    +R++EY++AF + V+PI++EF+P+LV+VSAGFDAA+GDPLG   VTP+C+ +MT ML  LANG+V+L LEGGYNL  I++CM+ C  +LLG  T  +      ++G E +    L    P W  L+   P
Sbjct:   13 TGLVFDARMELVSCPWERCF---PSSLRFHSEPQTLVMFNLKYFCVSRKPRMASVEELMFCHSQEYIRMMQSTAEMSDQERKSLSDTFDSVYLHKGSYDGALLAVGSVLQLVERVLTGDLRNGFALVRPPGHHAQRDLANGYCIFNNVAIAAQYALSQHQLQRVLIVDWDVHHGQGIQYTFQDDPRVLYFSVHRHEGGAFWPHLSEGDVTAVGRGIAKGFNINLPWSRTGMSDADYVTAFQQILMPVAYQFSPQLVLVSAGYDAALGDPKGEMCVSPPCFGLLTHMLMSLANGRLCLALEGGYNLEVTAAGVCATLHALLGDPVTSTGGSRQAKCSCSSERIDSSFKCLA---KSTSVSENDDKE----------------GKEIETDREKDPASTTEIGVMTTVTMETRI----------TGLVYDKRMRDHHNMWDRFHPEQPDRISVMFSRHEDLGLVGRCHMVTARLATEEELLTCHSVRHVNAMRETTSMKARDLHRCSADYNSVYLSPSSFDSACLAAGAALSLVEAAMCGQVSNGVAIIRPPGHHAESDVACGFCLFNTVALAAKHAQSLARRQIR-VLIVDWDVHHGNGTQHIFEDDPSVLYVSLHRYDGGRFFPCSEDANVDRVGTGPGKGFNVNVPWPGPYMRNAEYLAAFTSTVLPIAYEFDPELVLVSAGFDAAQGDPLGLCMVTPDCYAHMTHMLLGLANGRVLLFLEGGYNLTTIAECMAMCTRTLLGDSTLALGPLEPPQAGAERVLTSVLHTHSPLWHNLRIPAP 760          

HSP 2 Score: 294.664 bits (753), Expect = 3.029e-83
Identity = 144/388 (37.11%), Postives = 227/388 (58.51%), Query Frame = 2
Query:  188 EDLPAAQSNHGLYDNIELRINFPNKTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQ-LNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHE 1348
            E  PA+ +  G+   + +       T  VYD++M  H NMWD  + E+PDR+ V +    +  L+  C  + A+    E +   HS  HV  + +T +M A  L   S+ ++ V+   ++  ++ ++AG+ + +++A +  +  NG  +IRPPGHHA    A GFC+FN V +AAK+AQ L     ++LIVDWDVHHGN TQ+ F +   VLY+S+HRY+ G F+P   ++N D +G   G+G+N+N+P     M N++YL+ F S +LPIAYE++PELVL+SAGFD+A G P G   V P C+AHMTH L+ LA GRV++ LEGGY + ++ + + +   TL G +   L   + P    +  + + L      W +L +   ++ +
Sbjct:  380 EKDPASTTEIGVMTTVTMETRI---TGLVYDKRMRDHHNMWDRFHPEQPDRISVMFSRHEDLGLVGRCHMVTARLATEEELLTCHSVRHVNAMRETTSMKARDLHRCSADYNSVYLSPSSFDSACLAAGAALSLVEAAMCGQVSNGVAIIRPPGHHAESDVACGFCLFNTVALAAKHAQSLARRQIRVLIVDWDVHHGNGTQHIFEDDPSVLYVSLHRYDGGRFFPCSEDANVDRVGTGPGKGFNVNVPWPGPYMRNAEYLAAFTSTVLPIAYEFDPELVLVSAGFDAAQGDPLGLCMVTPDCYAHMTHMLLGLANGRVLLFLEGGYNLTTIAECMAMCTRTLLGDSTLALGPLEPPQAGAERVLTSVLHTHSPLWHNLRIPAPEDGQ 764          

HSP 3 Score: 137.117 bits (344), Expect = 7.400e-33
Identity = 62/133 (46.62%), Postives = 84/133 (63.16%), Query Frame = 2
Query: 3017 SGVSNSDIHHFLGLTSNDPLPERVYAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQVFCGRFVQAHMMQHFQNTRHAIVLSFVDLSSWCYECDSYVHNECLNHAKREAHIAKFGVPQP 3415
            SG+   D+   L   S    P   YAV+PL WC HL+ V   P    +D ++ C  C  + ENWLCL CY+ +CGR+V+ HM+QH + + HA+VLSF DLS+WCY CDSYVH+E L+ +KR A+ +KF    P
Sbjct: 1003 SGIHEDDVG--LAEASGWTPPSLCYAVKPLSWCPHLDAVTAIP-GGAVDPSSPCVDCGDSSENWLCLVCYEAYCGRYVRGHMLQHSEKSGHALVLSFADLSAWCYSCDSYVHHEALHESKRAAYRSKFDEEMP 1132          
BLAST of Histone deacetylase,putative vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005422.1 (pep scaffold:Pmarinus_7.0:GL501185:343872:431549:1 gene:ENSPMAG00000004812.1 transcript:ENSPMAT00000005422.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 291.197 bits (744), Expect = 1.273e-82
Identity = 153/389 (39.33%), Postives = 234/389 (60.15%), Query Frame = 2
Query: 1517 TCFVYDCRMENHM---NERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYV----------------ESLGNICQESPTIYHLFE-----EEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKR---PVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARG--DPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYP----TNQIINFPINKSGIEAIRKTLEYQKPYWKCLKFY 2584
            T  VYD  M  H       + HPE   R Q I+  L++  LL +C+++  R A+ +EI ++HS  +                 + LG++ Q+   ++ L        + ++++   HS  +A ++ G +  +  +V S   +NGFA++RPPGHHAE +  +GFCFFN+VAIAA     K++  ++KILI+DWDVHHGNGTQ  F+ + ++LY+SLHRYD G FFPGS  G+   VG     GFNVNIAW      P+ D+EY++AF  +V+PI++EF+PD+V+VS+GFDAA G   PLGG  V+ +CFG++T+ L  LA G+V++ALEGG++L  I D    C+S+LLG      +  I+    N + + ++ K ++ Q  YWK +  +
Sbjct:  609 TGVVYDSLMLKHQCSCGNNNNHPEHAGRIQSIWSRLQERGLLRKCERVRGRKATLEEIEMVHSEQHALLYSTNPLNRQKLDSKKLLGSLSQK---MFGLLPCGGLGVDSDTVWNELHSASAARMAAGCVSELACKVASGELKNGFAVVRPPGHHAEESAAMGFCFFNSVAIAAKLLQQKFN--VRKILIIDWDVHHGNGTQQAFYGDASILYLSLHRYDGGNFFPGS--GASEEVGTGAGIGFNVNIAWTGGLDPPMGDAEYLAAFRTVVLPIANEFSPDVVLVSSGFDAAEGHPPPLGGYKVSAKCFGHLTRQLMGLAGGRVVMALEGGHDLAAICDGSESCISALLGNELEPLSMDILQQQPNPNAVVSLEKVIDIQSKYWKSVAHF 990          

HSP 2 Score: 237.269 bits (604), Expect = 1.497e-64
Identity = 135/385 (35.06%), Postives = 210/385 (54.55%), Query Frame = 2
Query:  263 TAFVYDEQMLLH--SNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHV----------QLIEDTQTMTAIQLK--------ELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKT---NMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPE--GSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKF------DEPCDSVKETIQNCLKFLHFFWKSLS 1324
            T  VYD  ML H  S   +N + E   R++  +  + E  LL  C R++ ++   E I   HS+ H           Q ++  + + ++  K         L    D V+ + ++  A+ ++AG   E+   V     KNGF ++RPPGHHA ES A GFC FN+V IAAK  Q  ++ +KILI+DWDVHHGN TQ  FY  + +LY+S+HRY+ GNF+P    S  + +G   G G+N+NI         M +++YL+ F +++LPIA E++P++VL+S+GFD+A G P   G   V   CF H+T +LM LA GRVV+ LEGG+ + ++ D     ++ L G    +LE         +P  +   +++  +     +WKS++
Sbjct:  609 TGVVYDSLMLKHQCSCGNNNNHPEHAGRIQSIWSRLQERGLLRKCERVRGRKATLEEIEMVHSEQHALLYSTNPLNRQKLDSKKLLGSLSQKMFGLLPCGGLGVDSDTVWNELHSASAARMAAGCVSELACKVASGELKNGFAVVRPPGHHAEESAAMGFCFFNSVAIAAKLLQQKFNVRKILIIDWDVHHGNGTQQAFYGDASILYLSLHRYDGGNFFPGSGAS--EEVGTGAGIGFNVNIAWTGGLDPPMGDAEYLAAFRTVVLPIANEFSPDVVLVSSGFDAAEGHPPPLGGYKVSAKCFGHLTRQLMGLAGGRVVMALEGGHDLAAICDGSESCISALLGN---ELEPLSMDILQQQPNPNAVVSLEKVIDIQSKYWKSVA 988          
BLAST of Histone deacetylase,putative vs. Ensembl Sea Lamprey
Match: hdac4 (histone deacetylase 4 [Source:ZFIN;Acc:ZDB-GENE-061013-95])

HSP 1 Score: 223.787 bits (569), Expect = 1.312e-60
Identity = 129/310 (41.61%), Postives = 176/310 (56.77%), Query Frame = 2
Query: 1508 PNKTCF----VYDCRMENHM---NERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLG------------NICQESPTIYHLFE-----EEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKR---PVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDP--LGGLTVTPEC 2350
            PN+  F    VYD  M  H     + S HPE   R   I+  L+   LLS+C+ +  R AS  +I  +HS  +V   G             +    PT   L        + ++ + + HS  +A ++ G +  +   V S + +NGFAI+RPPGHHAE +  +GFC FN+VAIAA   L +    +++ILIVD DVHHGNGTQ  F+ +  VLY+SLHRYDNG FFPGS  G+ S VG    EGF VN++W      P+ D++Y++AF  +VMPI+ EF PD+V+VSAGFDA  G P  LGG  +T  C
Sbjct:  600 PNRPSFSTGVVYDTLMVRHQCSCGDDSNHPEHAGRIMAIWARLQQTGLLSKCEVIAGRKASLKDIQTVHSELHVLRYGTNPLNRQKLDTQGLLDAQPTQLMLLRCGGVGVDSDTYWSDAHSGSAARMAAGSVTTLAFHVASGQLKNGFAIVRPPGHHAEESAVMGFCVFNSVAIAAKLLLQELH--VRRILIVDLDVHHGNGTQQAFYNDPRVLYLSLHRYDNGNFFPGS--GASSEVGVGPGEGFTVNVSWTGGLDPPMGDADYLAAFRTVVMPIAMEFEPDVVLVSAGFDALDGHPPQLGGYKLTASC 905          

HSP 2 Score: 187.193 bits (474), Expect = 8.763e-49
Identity = 108/296 (36.49%), Postives = 161/296 (54.39%), Query Frame = 2
Query:  254 PNKTAF----VYDEQMLLH--SNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHV---------QLIEDTQTMTAIQLKEL--------SSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLN---KTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCP 1063
            PN+ +F    VYD  M+ H  S   D+ + E   R+   +  + +T LL  C  I  ++   + I   HS+ HV         +   DTQ +   Q  +L            D  + D ++  A+ ++AGS   +   V   + KNGF ++RPPGHHA ES   GFC+FN+V IAAK        ++ILIVD DVHHGN TQ  FYN  +VLY+S+HRY++GNF+P    S+   +G   G G+ +N+         M ++DYL+ F ++++PIA E+ P++VL+SAGFD+  G P
Sbjct:  600 PNRPSFSTGVVYDTLMVRHQCSCGDDSNHPEHAGRIMAIWARLQQTGLLSKCEVIAGRKASLKDIQTVHSELHVLRYGTNPLNRQKLDTQGLLDAQPTQLMLLRCGGVGVDSDTYWSDAHSGSAARMAAGSVTTLAFHVASGQLKNGFAIVRPPGHHAEESAVMGFCVFNSVAIAAKLLLQELHVRRILIVDLDVHHGNGTQQAFYNDPRVLYLSLHRYDNGNFFPGSGASS--EVGVGPGEGFTVNVSWTGGLDPPMGDADYLAAFRTVVMPIAMEFEPDVVLVSAGFDALDGHP 893          
BLAST of Histone deacetylase,putative vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001508.1 (pep scaffold:Pmarinus_7.0:GL487756:6232:7801:1 gene:ENSPMAG00000001367.1 transcript:ENSPMAT00000001508.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 119.013 bits (297), Expect = 1.312e-31
Identity = 52/120 (43.33%), Postives = 83/120 (69.17%), Query Frame = 2
Query:  440 HSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQF 799
            +S  ++ L+E T++M+  +LK LS +    FF  +T   + ++ G+T++++ AV+    +NG  L+RPPGHH+  +EA+GFCIFNNV IAA+ A+  +  ++ILIVDWD+HHG  TQ+ F
Sbjct:    1 YSAEYLALVESTESMSLEELKALSDKTMDAFFHPDTYACARLALGATLQLVDAVVTGAVRNGVALVRPPGHHSQRNEANGFCIFNNVAIAAERAKRTHGLRRILIVDWDIHHGQGTQFIF 120          

HSP 2 Score: 97.0561 bits (240), Expect = 5.652e-24
Identity = 44/87 (50.57%), Postives = 58/87 (66.67%), Query Frame = 2
Query: 1796 SYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQF 2056
            +Y  A L+ G  L ++D V +    NG A++RPPGHH++ N   GFC FNNVAIAA  A  K +  +++ILIVDWD+HHG GTQ  F
Sbjct:   36 TYACARLALGATLQLVDAVVTGAVRNGVALVRPPGHHSQRNEANGFCIFNNVAIAAERA--KRTHGLRRILIVDWDIHHGQGTQFIF 120          
BLAST of Histone deacetylase,putative vs. Ensembl Sea Lamprey
Match: hdac3 (histone deacetylase 3 [Source:NCBI gene;Acc:393965])

HSP 1 Score: 92.8189 bits (229), Expect = 4.724e-20
Identity = 102/431 (23.67%), Postives = 179/431 (41.53%), Query Frame = 2
Query: 1571 HPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQH------------SYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPG-HHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINFPINKSGIEAIRKTLEYQKPYWKCLKFYEPLVVTYTEISP---NQTNPAALDNIVQIDTNTL-----AESVRQLGIVEVTFQTEQSIEETL-SQPRNDTFITEPNSSN 2797
            HP  P R  +    +    L  +    +   AS+ ++   HS  Y++ L  +   +P     F +  N+  +                Y  A L     LN  +++C        AI    G HHA+     GFC+ N++ IA    L KY     ++L +D D+HHG+G Q  F+    V+ +S H+Y N  FFPG+  G    VG +    ++VN+   +  + D  Y   F  I+  +   + P  +++  G D+   D LG   ++ +  G     + S  N  +++   GGY +  ++ C +        Y T+ ++N PI+             + PY + L+++ P    + +IS    NQ +   L+ I Q     L     A SV+   +       E+  E    ++P  D  I +P+++N
Sbjct:    4 HPMKPHRLALTHSLVLHYGLHKKMMVYKPYRASQHDMCRFHSEEYIDFLQRV---TPHNIQGFTKSLNTFNVGDDCPVFPGLFEFCARYTGASLQGATQLN--NKMCD------IAINWSGGLHHAKKFEASGFCYVNDIVIAI-LELLKYH---PRVLYIDIDIHHGDGVQEAFYLTDRVMTVSFHKYGN-YFFPGT--GDMYEVGAESGRYYSVNVPL-RDGIDDQCYRLLFQPIIKQVMDFYQPTCIVLQCGADSLGCDRLGCFNLSIKGHGECVDFVKSF-NIPLLVLGGGGYTVRNVARCWT--------YETSLLMNDPISD------------ELPYNEYLEYFSPDFSLHPDISTRIENQNSKQYLEQIRQSIFENLKMLNHAPSVQIHEVPSDLLSYERKDEPNPDARPGTDDAIVKPDAAN 394          

HSP 2 Score: 86.6557 bits (213), Expect = 5.793e-18
Identity = 58/181 (32.04%), Postives = 94/181 (51.93%), Query Frame = 2
Query:  650 HHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDS----AIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESL 1180
            HHA + EASGFC  N++ IA    +L     ++L +D D+HHG+  Q  FY T +V+ +S H+Y  GN++       Y+ +GA  GR Y++N+PL +  + +  Y  +F  II  +   Y P  +++  G DS     +GC   S+  H  C   +    + L     +VL  GGY + ++
Sbjct:  116 HHAKKFEASGFCYVNDIVIAI--LELLKYHPRVLYIDIDIHHGDGVQEAFYLTDRVMTVSFHKY--GNYFFPGTGDMYE-VGAESGRYYSVNVPL-RDGIDDQCYRLLFQPIIKQVMDFYQPTCIVLQCGADSLGCDRLGCFNLSIKGHGECVDFVKSFNIPL-----LVLGGGGYTVRNV 285          
BLAST of Histone deacetylase,putative vs. Ensembl Yeast
Match: HDA1 (Putative catalytic subunit of a class II histone deacetylase complex; role in azole resistance via Hsp90p, and in the heat shock response; Hda1p interacts with the Hda2p-Hda3p subcomplex to form an active tetramer; deletion increases histone H2B, H3 and H4 acetylation; other members of the HDA1 histone deacetylase complex are Hda2p and Hda3p [Source:SGD;Acc:S000004966])

HSP 1 Score: 290.426 bits (742), Expect = 4.821e-85
Identity = 151/379 (39.84%), Postives = 213/379 (56.20%), Query Frame = 2
Query: 1508 PNKTCFVYDCRMENHMNERSI-------HPESPRRTQMIFEFLRDNSLLSR------------CKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINFPINKSG---IEAIRKTLEYQKPYWKCLK 2578
            P KT   YD RM  H    +        HPE PRR   I++ L +N L++               ++  R A+ +EI  +H+  ++E + +  + S        E+ +S+Y N  SY SA L CG  +     V   R +N  A++RPPGHHAE     GFC F+NVA+AA   L  Y ES+++I+I+DWD+HHGNGTQ  F+ +  VLY+SLHR++ G ++PG+  G     G    EGFN NI W    V D+EY+ AF  +VMP+  EF PDLVI+S+GFDAA GD +G   VTP C+G+MT ML SLA G + + LEGGYNL+ I+         L+G P +++ + P++      IE I K +  Q  YW C +
Sbjct:   55 PLKTGLCYDVRMRYHAKIFTSYFEYIDPHPEDPRRIYRIYKILAENGLINDPTLSGVDDLGDLMLKIPVRAATSEEILEVHTKEHLEFIESTEKMSREELLKETEKGDSVYFNNDSYASARLPCGGAIEACKAVVEGRVKNSLAVVRPPGHHAEPQAAGGFCLFSNVAVAAKNILKNYPESVRRIMILDWDIHHGNGTQKSFYQDDQVLYVSLHRFEMGKYYPGTIQGQYDQTGEGKGEGFNCNITWPVGGVGDAEYMWAFEQVVMPMGREFKPDLVIISSGFDAADGDTIGQCHVTPSCYGHMTHMLKSLARGNLCVVLEGGYNLDAIARSALSVAKVLIGEPPDELPD-PLSDPKPEVIEMIDKVIRLQSKYWNCFR 432          

HSP 2 Score: 263.462 bits (672), Expect = 1.336e-75
Identity = 132/375 (35.20%), Postives = 213/375 (56.80%), Query Frame = 2
Query:  254 PNKTAFVYDEQMLLHSNMWDNLYFE-------RPDRLRVCYEGICETNLLED------------CIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNY--STQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKL-EKFDEPCDSVKETIQNCLKFLHFFW 1312
            P KT   YD +M  H+ ++ + YFE        P R+   Y+ + E  L+ D             ++I  +   +E I   H++ H++ IE T+ M+  +L + + + D V+F+N++  ++ +  G  IE  KAV++ R KN   ++RPPGHHA    A GFC+F+NV +AAK    NY  S ++I+I+DWD+HHGN TQ  FY   +VLY+S+HR+E G ++P   +  YD  G  +G G+N NI      + +++Y+  F  +++P+  E+ P+LV+IS+GFD+A G   G   V P+C+ HMTH L  LARG + V+LEGGY ++++  S +     L G+ P +L +   +P   V E I   ++    +W
Sbjct:   55 PLKTGLCYDVRMRYHAKIFTS-YFEYIDPHPEDPRRIYRIYKILAENGLINDPTLSGVDDLGDLMLKIPVRAATSEEILEVHTKEHLEFIESTEKMSREELLKETEKGDSVYFNNDSYASARLPCGGAIEACKAVVEGRVKNSLAVVRPPGHHAEPQAAGGFCLFSNVAVAAKNILKNYPESVRRIMILDWDIHHGNGTQKSFYQDDQVLYVSLHRFEMGKYYPGTIQGQYDQTGEGKGEGFNCNITWPVGGVGDAEYMWAFEQVVMPMGREFKPDLVIISSGFDAADGDTIGQCHVTPSCYGHMTHMLKSLARGNLCVVLEGGYNLDAIARSALSVAKVLIGEPPDELPDPLSDPKPEVIEMIDKVIRLQSKYW 428          
BLAST of Histone deacetylase,putative vs. Ensembl Yeast
Match: HOS2 (Histone deacetylase and subunit of Set3 and Rpd3L complexes; required for gene activation via specific deacetylation of lysines in H3 and H4 histone tails; subunit of the Set3 complex, a meiotic-specific repressor of sporulation specific genes that contains deacetylase activity; co-localizes with Cmr1p in nuclear foci in response to DNA damage by MMS [Source:SGD;Acc:S000003162])

HSP 1 Score: 114.005 bits (284), Expect = 5.846e-27
Identity = 94/329 (28.57%), Postives = 160/329 (48.63%), Query Frame = 2
Query: 1472 YELRTKN-----AFNN-YPNKTCFVYDCRMENHMNERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESP-TIYHLFEEEFN-----SIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPG-HHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGG 2419
            Y+++TK       FN+ Y  +  + ++ ++ +H +    HP  P R  +    +    L       E+R A++DE+   HS +YV  L  +  E+   +     E FN      I+ N + Y +  L  G  L+   ++ +++S+   AI    G HHA+ N P GFC+ N++ ++    L +Y     +IL +D D+HHG+G Q  F+T   V  +S H+Y NG FFPG+  G  + +G D  + F +N+   +  + D  YI+ F +IV P+   F P L++   G D+   D LG   +  +  G   + + S   G  +L + GG
Sbjct:    7 YDVKTKENEPLFEFNSAYSPRVSYHFNSKV-SHYHYGVKHPMKPFRLMLTDHLVSSYGLHKIMDLYETRSATRDELLQFHSEDYVNFLSKVSPENANKLPRGTLENFNIGDDCPIFQNLYDYTT--LYTGASLDATRKLINNQSD--IAINWSGGLHHAKKNSPSGFCYVNDIVLSI-LNLLRYH---PRILYIDIDLHHGDGVQEAFYTTDRVFTLSFHKY-NGEFFPGT--GDLTEIGCDKGKHFALNVPL-EDGIDDDSYINLFKSIVDPLIMTFKPTLIVQQCGADSLGHDRLGCFNLNIKAHGECVKFVKSF--GLPMLVVGGG 320          

HSP 2 Score: 88.9669 bits (219), Expect = 8.810e-19
Identity = 62/236 (26.27%), Postives = 121/236 (51.27%), Query Frame = 2
Query:  419 NELIYYSHSQSHVQLI-----EDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPG--HHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDS----AIGCPEGSMDVHPAC 1093
            +EL+ + HS+ +V  +     E+   +    L+  +   DC  F N     +  + G++++  + ++++++      I   G  HHA ++  SGFC  N++ + +    L Y   +IL +D D+HHG+  Q  FY T +V  +S H+Y +G F+P     +   IG ++G+ + +N+PL +  + +  Y+++F SI+ P+   + P L++   G DS     +GC   ++  H  C
Sbjct:   79 DELLQF-HSEDYVNFLSKVSPENANKLPRGTLENFNIGDDCPIFQNLYDYTTLYT-GASLDATRKLINNQSD---IAINWSGGLHHAKKNSPSGFCYVNDI-VLSILNLLRYHP-RILYIDIDLHHGDGVQEAFYTTDRVFTLSFHKY-NGEFFPG--TGDLTEIGCDKGKHFALNVPL-EDGIDDDSYINLFKSIVDPLIMTFKPTLIVQQCGADSLGHDRLGCFNLNIKAHGEC 303          
BLAST of Histone deacetylase,putative vs. Ensembl Yeast
Match: RPD3 (Histone deacetylase, component of both the Rpd3S and Rpd3L complexes; regulates transcription, silencing, autophagy and other processes by influencing chromatin remodeling; forms at least two different complexes which have distinct functions and members; Rpd3(L) recruitment to the subtelomeric region is regulated by interaction with the arginine methyltransferase, Hmt1p [Source:SGD;Acc:S000005274])

HSP 1 Score: 106.301 bits (264), Expect = 1.721e-24
Identity = 88/331 (26.59%), Postives = 156/331 (47.13%), Query Frame = 2
Query:  224 YDNIELRINFPNKTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIE----DTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPG-HHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWP---KLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDS----AIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESL 1180
            +D I ++ +   + A+ YD  +  ++  +   +  +P R+R+ +  I    L +     +AK    + +   H+  ++  +     D   M   +  + +   DC  FD   +  S IS G ++E   A   +R K    +    G HHA +SEASGFC  N++ +     +L     ++L +D DVHHG+  +  FY T +V+  S H+Y  G F+P   +LR+     IG   G+ Y +N+PL +  + ++ Y S+F  +I  I   Y P  V++  G DS     +GC   SM+ H  C  ++    + +     +V+  GGY M ++
Sbjct:    8 FDPITVKPSDKRRVAYFYDADVGNYA--YGAGHPMKPHRIRMAHSLIMNYGLYKKMEIYRAKPATKQEMCQFHTDEYIDFLSRVTPDNLEMFKRESVKFNVGDDCPVFDGLYEYCS-ISGGGSME--GAARLNRGKCDVAVNYAGGLHHAKKSEASGFCYLNDIVLGI--IELLRYHPRVLYIDIDVHHGDGVEEAFYTTDRVMTCSFHKY--GEFFPGTGELRD-----IGVGAGKNYAVNVPL-RDGIDDATYRSVFEPVIKKIMEWYQPSAVVLQCGGDSLSGDRLGCFNLSMEGHANCVNYVKSFGIPM-----MVVGGGGYTMRNV 318          

HSP 2 Score: 99.7525 bits (247), Expect = 2.243e-22
Identity = 75/315 (23.81%), Postives = 142/315 (45.08%), Query Frame = 2
Query: 1514 KTCFVYDCRMENHMNERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFN-----SIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPG-HHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVIS 2440
            +  + YD  + N+      HP  P R +M    + +  L  + +   ++ A+K E+   H+  Y++ L  +  ++  ++     +FN      ++   + Y S  +S G  +     +  +R +   A+    G HHA+ +   GFC+ N++ +     L +Y     ++L +D DVHHG+G +  F+T   V+  S H+Y  G FFPG+ +     VG       NV +   +  + D+ Y S F  ++  I   + P  V++  G D+  GD LG   ++ E   N    + S     +++   GGY +  ++
Sbjct:   20 RVAYFYDADVGNYAYGAG-HPMKPHRIRMAHSLIMNYGLYKKMEIYRAKPATKQEMCQFHTDEYIDFLSRVTPDNLEMFKRESVKFNVGDDCPVFDGLYEYCS--ISGGGSMEGAARL--NRGKCDVAVNYAGGLHHAKKSEASGFCYLNDIVLGI-IELLRYH---PRVLYIDIDVHHGDGVEEAFYTTDRVMTCSFHKY--GEFFPGTGELRDIGVGAGKNYAVNVPL---RDGIDDATYRSVFEPVIKKIMEWYQPSAVVLQCGGDSLSGDRLGCFNLSMEGHANCVNYVKSFGIPMMVVG-GGGYTMRNVA 319          
BLAST of Histone deacetylase,putative vs. Ensembl Yeast
Match: HOS3 (Trichostatin A-insensitive homodimeric histone deacetylase (HDAC); specificity in vitro for histones H3, H4, H2A, and H2B; similar to Hda1p, Rpd3p, Hos1p, and Hos2p; deletion results in increased histone acetylation at rDNA repeats [Source:SGD;Acc:S000006037])

HSP 1 Score: 73.1738 bits (178), Expect = 1.574e-13
Identity = 70/277 (25.27%), Postives = 121/277 (43.68%), Query Frame = 2
Query:  623 GFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQ------------------------YQFYNTSKVLYISIHRYEDGNFWPK---------LRESNYDYIGANEGRGYNINIPLNKTN-----MTNSDYLSI-------FHSIILPIAYEYNP--ELVLISAGFDSA----IGCPEGSMDVHPACFAHMTHKLMDLAR----GRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNC 1288
             F  IRPPGHH      SGFC+ NN  +A +YA   Y+   ++++D+D+HHG+ TQ                         +F    KV Y S+H   D N +P          ++ ++   + +++   +NI++    T      +  + Y ++       F S  L +  +  P   LV+ISAGFD++          S++V  + +   T   + LA+    G+V+ L+EGGY  +++   V   L  L  +   K    ++    VKE ++ C
Sbjct:  186 AFVAIRPPGHHCHYGTPSGFCLLNNAHVAIEYAYDTYNVTHVVVLDFDLHHGDGTQDICWKRAGFKPEEEPEDSSYDDFGKKFAEFPKVGYFSMH---DINSFPTESGFATKENIKNASTCIMNSHDLNIWNIHLSKWTTEEEFNVLYRTKYRTLFAKADEFFRSAKLEMNQQGRPFKGLVVISAGFDASEFEQTSMQRHSVNVPTSFYTTFTKDALKLAQMHCHGKVLSLMEGGYSDKAICSGVFAHLIGLQNQDWVKEWGSEQ---VVKEIVRGC 456          

HSP 2 Score: 70.4774 bits (171), Expect = 9.987e-13
Identity = 70/293 (23.89%), Postives = 117/293 (39.93%), Query Frame = 2
Query: 1865 SENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNK------------------------NVLYISLHRYDNGLFFPGST---------DGSPSAVGGDDAEGFNVNIA-WNKRPVRDSEYISA-----------FINIVMPISHEFNP--DLVIVSAGFDAARGDPLG----GLTVTPECFGNMTQMLTSLA----NGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINFPINKSGIEAIRKTLEYQKPYWKCLK 2578
            S   F  IRPPGHH     P GFC  NN  +A  YA   Y  ++  ++++D+D+HHG+GTQ   W                            V Y S+H  ++   FP  +         + S   +   D   +N++++ W      +  Y +            F +  + ++ +  P   LV++SAGFDA+  +        + V    +   T+    LA    +GKV+  +EGGY+   I  C S   + L+G      +         + +++ +   KP WK  K
Sbjct:  183 SNRAFVAIRPPGHHCHYGTPSGFCLLNNAHVAIEYAYDTY--NVTHVVVLDFDLHHGDGTQDICWKRAGFKPEEEPEDSSYDDFGKKFAEFPKVGYFSMHDINS---FPTESGFATKENIKNASTCIMNSHDLNIWNIHLSKWTTEEEFNVLYRTKYRTLFAKADEFFRSAKLEMNQQGRPFKGLVVISAGFDASEFEQTSMQRHSVNVPTSFYTTFTKDALKLAQMHCHGKVLSLMEGGYSDKAI--C-SGVFAHLIGLQNQDWVK---EWGSEQVVKEIVRGCKPAWKPYK 464          
BLAST of Histone deacetylase,putative vs. Ensembl Yeast
Match: HOS1 (Class I histone deacetylase (HDAC) family member; deacetylates Smc3p on lysine residues at anaphase onset; has sequence similarity to Hda1p, Rpd3p, Hos2p, and Hos3p; interacts with the Tup1p-Ssn6p corepressor complex [Source:SGD;Acc:S000006272])

HSP 1 Score: 68.1662 bits (165), Expect = 4.005e-12
Identity = 63/207 (30.43%), Postives = 93/207 (44.93%), Query Frame = 2
Query: 1823 GLLLNVIDEVCSDRSENGFAIIRPPG-HHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVR---DSEYISAFIN-IVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGN-MTQMLTSLANGKVILALEGGYN 2425
            G  LN++D +    +E    I    G HHA      GFC+ N+V +     L K    + KI  VD+D+HHG+G +  F  +K +  IS+H Y+ G FFPG+  GS S    D      VNI     P++   D  Y+    + IV P+     P+ +I+  G D   GD      +T       +  ++ S     + L   GGYN
Sbjct:  185 GATLNLLDHLSP--TERLIGINWDGGRHHAFKQRASGFCYINDVVLLIQ-RLRK--AKLNKITYVDFDLHHGDGVEKAFQYSKQIQTISVHLYEPG-FFPGT--GSLSDSRKDKNV---VNI-----PLKHGCDDNYLELIASKIVNPLIERHEPEALIIECGGDGLLGDRFNEWQLTIRGLSRIIINIMKSYPRAHIFLLGGGGYN 375          

HSP 2 Score: 65.855 bits (159), Expect = 1.951e-11
Identity = 54/180 (30.00%), Postives = 85/180 (47.22%), Query Frame = 2
Query:  650 HHAMESEASGFCIFNNVGI---AAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWP---KLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHS-IILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMD-LARGRVVVLLEGGY 1165
            HHA +  ASGFC  N+V +     + A+LN    KI  VD+D+HHG+  +  F  + ++  IS+H YE G F+P    L +S  D           +NIPL      + +YL +  S I+ P+   + PE ++I  G D  +G       +     + +   +M    R  + +L  GGY
Sbjct:  210 HHAFKQRASGFCYINDVVLLIQRLRKAKLN----KITYVDFDLHHGDGVEKAFQYSKQIQTISVHLYEPG-FFPGTGSLSDSRKD--------KNVVNIPLKHG--CDDNYLELIASKIVNPLIERHEPEALIIECGGDGLLGDRFNEWQLTIRGLSRIIINIMKSYPRAHIFLLGGGGY 374          
BLAST of Histone deacetylase,putative vs. Ensembl Nematostella
Match: EDO33321 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SSG8])

HSP 1 Score: 301.212 bits (770), Expect = 1.689e-92
Identity = 148/369 (40.11%), Postives = 224/369 (60.70%), Query Frame = 2
Query:  263 TAFVYDEQMLLHSNMWDNL---------YFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAK------NGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLS 1324
            T  VYD++M  H N+WD            +E PDR+   YE   E  LL+ C +I ++    E +   HS+ H+  ++ TQ M    L  L  ++D ++   +    + +S G T+  ++ V  +++       N    +RPPGHHA    A G+C FNNV IAAK AQ  +  Q+ILIVDWD+HHGN TQ  F +   VLY S+HRY+  NF+P   ++NYD +G  +G+G+N+N+P NK+++ ++DY++ F  I+LPIAYE++P++VL+SAGFDSA G P+G  D+ P  + H+T+ LM LA G+VVV+LEGGY + S+ +S+    +TL G   P+L+    PC SV ++I N +     FWK+L+
Sbjct:    1 TGLVYDDRMKRHVNIWDKYVYINTLICSLYEVPDRIGRPYEKHKEYGLLDRCYKIPSRHATEEDLLCLHSKEHIDKMKSTQDMKPRDLFNLGEEYDSIYMSKDVYDCALLSCGCTLAAVEHVATNKSSKHSIHINQLFFLRPPGHHADADSAMGYCFFNNVAIAAKLAQQRWGMQRILIVDWDIHHGNGTQNLFESDPSVLYFSLHRYDHANFYPFSAQANYDIVGKGQGKGFNVNVPWNKSHIGDADYIAAFQQILLPIAYEFDPDIVLVSAGFDSARGDPKGYCDITPEGYCHLTNMLMSLAGGKVVVILEGGYNITSVAESMCSCTSTLLGDPCPRLDGPMVPCQSVLKSISNVVNVHKQFWKNLT 369          

HSP 2 Score: 293.893 bits (751), Expect = 9.491e-90
Identity = 151/371 (40.70%), Postives = 236/371 (63.61%), Query Frame = 2
Query: 1517 TCFVYDCRMENHMN--ERSIHP--------ESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSE------NGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINFPI--NKSGIEAIRKTLEYQKPYWKCL 2575
            T  VYD RM+ H+N  ++ ++         E P R    +E  ++  LL RC ++ SR A+++++  +HS  +++ + +     P       EE++SIY+++  Y  ALLSCG  L  ++ V +++S       N    +RPPGHHA+ +  +G+CFFNNVAIAA  A  ++   +++ILIVDWD+HHGNGTQ+ F ++ +VLY SLHRYD+  F+P S   +   VG    +GFNVN+ WNK  + D++YI+AF  I++PI++EF+PD+V+VSAGFD+ARGDP G   +TPE + ++T ML SLA GKV++ LEGGYN+  +++ M  C S+LLG P  + ++ P+   +S +++I   +   K +WK L
Sbjct:    1 TGLVYDDRMKRHVNIWDKYVYINTLICSLYEVPDRIGRPYEKHKEYGLLDRCYKIPSRHATEEDLLCLHSKEHIDKMKSTQDMKPRDLFNLGEEYDSIYMSKDVYDCALLSCGCTLAAVEHVATNKSSKHSIHINQLFFLRPPGHHADADSAMGYCFFNNVAIAAKLAQQRWG--MQRILIVDWDIHHGNGTQNLFESDPSVLYFSLHRYDHANFYPFSAQANYDIVGKGQGKGFNVNVPWNKSHIGDADYIAAFQQILLPIAYEFDPDIVLVSAGFDSARGDPKGYCDITPEGYCHLTNMLMSLAGGKVVVILEGGYNITSVAESMCSCTSTLLGDPCPR-LDGPMVPCQSVLKSISNVVNVHKQFWKNL 368          
BLAST of Histone deacetylase,putative vs. Ensembl Nematostella
Match: EDO35756 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SKN6])

HSP 1 Score: 269.24 bits (687), Expect = 3.358e-80
Identity = 145/361 (40.17%), Postives = 210/361 (58.17%), Query Frame = 2
Query: 1571 HPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQ-----ESPTIYHL----------FEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKR---PVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDP--LGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLG-----YPTNQIINFPINKSGIEAIRKTLEYQKPYWKCLK 2578
            HPE P R Q I+  L++  +++ C ++  R A+  EI  +HS  +    G   Q     E  TI  L             + ++I+   HS  +A ++ G ++ +  +V +   +NG AI+RPPGHHAE +  +GFC+FNNVAIAA   L +   SI ++LIVDWD+HHGNGTQ  F+ + +VLYISLHR+D+G FFPG+  G     G     G+NVNIAW+     P  D+EY++AF ++V+PI+ EF PD+++VS GFDAA G    LGG  V+  CF ++T  L  LA+G+V+LALEGGY+L  + D    C+ +LL       P   +   P N + I  + KT+  Q  YW  +K
Sbjct:   14 HPEHPGRLQSIWARLQETGVVNMCDRVRPRKATLAEILSVHSEQHTMLFGGSTQCRTKAEDGTITTLKCFSSLPCGGMGVDGDTIWNEVHSANAARMAVGCVVELTQKVAAQEIKNGMAIVRPPGHHAEAHQAMGFCYFNNVAIAAR--LLRLKMSIDRVLIVDWDIHHGNGTQQMFYDDPHVLYISLHRHDDGTFFPGT--GKAEECGAGIGVGYNVNIAWSGGLDPPYGDAEYLAAFRSVVIPIAKEFQPDIILVSCGFDAAAGHSPQLGGYKVSAPCFAHLTNQLMDLADGRVVLALEGGYSLPSLCDAAEACLRALLSDTLPEIPKESLKRAP-NPNAIAVLEKTIAIQSRYWSSVK 369          

HSP 2 Score: 228.794 bits (582), Expect = 7.550e-66
Identity = 126/326 (38.65%), Postives = 188/326 (57.67%), Query Frame = 2
Query:  326 ERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIE-DTQTMTAIQ------LKELSS--------QHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKT---NMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIG-CPE-GSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEK 1243
            E P RL+  +  + ET ++  C R++ ++     I   HS+ H  L    TQ  T  +      LK  SS          D ++ + ++  A+ ++ G  +E+ + V     KNG  ++RPPGHHA   +A GFC FNNV IAA+  +L  S  ++LIVDWD+HHGN TQ  FY+   VLYIS+HR++DG F+P   ++  +  GA  G GYN+NI  +        +++YL+ F S+++PIA E+ P+++L+S GFD+A G  P+ G   V   CFAH+T++LMDLA GRVV+ LEGGY + SL D+    L  L     P++ K
Sbjct:   16 EHPGRLQSIWARLQETGVVNMCDRVRPRKATLAEILSVHSEQHTMLFGGSTQCRTKAEDGTITTLKCFSSLPCGGMGVDGDTIWNEVHSANAARMAVGCVVELTQKVAAQEIKNGMAIVRPPGHHAEAHQAMGFCYFNNVAIAARLLRLKMSIDRVLIVDWDIHHGNGTQQMFYDDPHVLYISLHRHDDGTFFPGTGKA--EECGAGIGVGYNVNIAWSGGLDPPYGDAEYLAAFRSVVIPIAKEFQPDIILVSCGFDAAAGHSPQLGGYKVSAPCFAHLTNQLMDLADGRVVLALEGGYSLPSLCDAAEACLRALLSDTLPEIPK 339          
BLAST of Histone deacetylase,putative vs. Ensembl Nematostella
Match: EDO32559 (Histone deacetylase [Source:UniProtKB/TrEMBL;Acc:A7SUP8])

HSP 1 Score: 102.449 bits (254), Expect = 4.558e-23
Identity = 56/194 (28.87%), Postives = 95/194 (48.97%), Query Frame = 2
Query: 1901 HHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYP 2482
            HHA+ +   GFC+ N++ +     + K  E   ++L VD DVHHG+G +  F     V+ +S H+Y +G FFPG+  GS   VG      + +N+   K  + D  ++  F  ++  +  +F PD ++   G D+  GDP+    +T    G   + L    N  +++   GGYN+   S C ++    +L  P
Sbjct:  149 HHAQRDEAAGFCYINDIVLG----ILKLREKYDRVLYVDLDVHHGDGVEDAFSFTPKVMTVSFHKYSSG-FFPGT--GSCCQVGHGKGRYYTLNVPL-KDGITDRPFVEVFTRVMSRVKAKFKPDAIVCQCGVDSLAGDPMKAFNLTQFAVGRCVKYLQGW-NLPMLVLGGGGYNMVNTSRCWTYVTGVILDRP 333          

HSP 2 Score: 90.5077 bits (223), Expect = 3.762e-19
Identity = 64/221 (28.96%), Postives = 104/221 (47.06%), Query Frame = 2
Query:  497 LKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEG 1159
            L E    +DC  F++     S I AG+T+     +   +AK      +   HHA   EA+GFC  N+  I     +L     ++L VD DVHHG+  +  F  T KV+ +S H+Y  G F+P     +   +G  +GR Y +N+PL K  +T+  ++ +F  ++  +  ++ P+ ++   G DS  G P  + +            L   A GR V  L+G
Sbjct:  100 LVEFGLGYDCPPFEDMYDCVSMI-AGATLLAADMLKTGQAKVAVNW-QGGWHHAQRDEAAGFCYIND--IVLGILKLREKYDRVLYVDLDVHHGDGVEDAFSFTPKVMTVSFHKYSSG-FFPG--TGSCCQVGHGKGRYYTLNVPL-KDGITDRPFVEVFTRVMSRVKAKFKPDAIVCQCGVDSLAGDPMKAFN------------LTQFAVGRCVKYLQG 300          
BLAST of Histone deacetylase,putative vs. Ensembl Nematostella
Match: EDO49920 (Histone deacetylase [Source:UniProtKB/TrEMBL;Acc:A7RFA3])

HSP 1 Score: 102.449 bits (254), Expect = 8.693e-23
Identity = 74/267 (27.72%), Postives = 124/267 (46.44%), Query Frame = 2
Query:  329 RPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIE----DTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPG-HHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWP---KLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDS----AIGCPEGSMDVHPAC 1093
            +P R+R+ +  +    L       +  +   E I   HS  +++ ++    D  +    Q++  +   DC  FD   +     + GS   +  AV  ++      +    G HHA +SEASGFC  N++ +A    +L    Q++L +D D+HHG+  +  FY T +V+ +S H+Y  G ++P    LR+     IGA  G+ Y +N PL +  + +  Y  IF  II  +   Y P  V++  G DS     +GC   S+  H  C
Sbjct:   32 KPHRIRMTHNLLLNYGLYRKMEIYRPHKAAMEEITRYHSDDYIKFLKSIRPDNMSDYTKQMQRFNVGEDCPVFDGLYEFCQLSTGGS---IAGAVKLNKQHTDIAINWSGGLHHAKKSEASGFCYVNDIVLAI--LELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKY--GEYFPGTGDLRD-----IGAGRGKYYAVNFPL-RDGIEDESYQQIFQPIITKVIEIYQPNAVVLQCGADSLAGDRLGCFNLSLKGHAKC 285          

HSP 2 Score: 101.293 bits (251), Expect = 1.863e-22
Identity = 83/325 (25.54%), Postives = 150/325 (46.15%), Query Frame = 2
Query: 1511 NKTCFVYDCRMENHMNERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFN---SIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPG-HHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLL 2473
             K C+ YD  + N+   +  HP  P R +M    L +  L  + +      A+ +EI   HS +Y++ L +I  ++ + Y    + FN      +    Y    LS G   ++   V  ++     AI    G HHA+ +   GFC+ N++ +A    L KY +   ++L +D D+HHG+G +  F+T   V+ +S H+Y  G +FPG+  G    +G    + + VN    +  + D  Y   F  I+  +   + P+ V++  G D+  GD LG   ++ +      + + S  N  +++   GGY +  ++ C ++  S  L
Sbjct:   10 KKVCYYYDGDIGNYYYGQG-HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKAAMEEITRYHSDDYIKFLKSIRPDNMSDYTKQMQRFNVGEDCPVFDGLYEFCQLSTGG--SIAGAVKLNKQHTDIAINWSGGLHHAKKSEASGFCYVNDIVLAI-LELLKYHQ---RVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKY--GEYFPGT--GDLRDIGAGRGKYYAVNFPL-RDGIEDESYQQIFQPIITKVIEIYQPNAVVLQCGADSLAGDRLGCFNLSLKGHAKCVEFVKSF-NLPLLILGGGGYTIRNVARCWTYETSVAL 321          
BLAST of Histone deacetylase,putative vs. Ensembl Nematostella
Match: EDO39062 (Histone deacetylase [Source:UniProtKB/TrEMBL;Acc:A7SB64])

HSP 1 Score: 97.8265 bits (242), Expect = 2.460e-21
Identity = 94/397 (23.68%), Postives = 168/397 (42.32%), Query Frame = 2
Query: 1571 HPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLG-----------------NICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPG-HHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINFPINKSGIEAIRKTLEYQKPYWKCLKFYEPLVVTYTEISP---NQTNPAALDNIVQIDTNTLAESVRQL 2698
            HP  P R  +    + +  L  + +  +   A+  ++   HS +Y++ L                  N+ ++ P    LF+  F SIY        A L   + LN    +C        AI    G HHA+     GFC+ N++ +A    L KY     ++L VD D+HHG+G Q  F+    V+ +S H+Y N  FFPG+  G    VG D+   ++VN+   +  + D  Y S F  ++  +   + P  +++  G D+   D LG   ++ +  G   + + +     ++L   GGY +  ++ C ++  S L                    + + +  + PY   L+++ P    + +I+    NQ     LD I Q    T++E+++ L
Sbjct:   23 HPMKPHRLTLTHNLVFNYGLHKKMEVYKPYRATNHDMSRFHSSDYIDFLSRVTIQNNPNLSKSMSDFNVGEDCPVFPGLFD--FCSIYT------GASLEGAVRLN--QGICD------IAINWAGGLHHAKKCEASGFCYVNDIVVAI-LELLKYH---NRVLYVDIDIHHGDGVQEAFYLTDRVMTVSFHKYGNH-FFPGT--GDMYEVGVDNGRLYSVNVPL-RDGIDDQNYASLFKPVINMVIDHYQPTCIVLQCGADSLGCDRLGCFNLSTKGHGECVRFMKTFNLPMLVLG-GGGYTIRNVARCWAYETSLL--------------------VDQQVSTEIPYNDYLEYFGPDFSLHPDIASRIENQNTKQYLDQIRQ----TVSENLKNL 370          

HSP 2 Score: 90.8929 bits (224), Expect = 4.470e-19
Identity = 74/236 (31.36%), Postives = 119/236 (50.42%), Query Frame = 2
Query:  497 LKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFC--LIRPPG--HHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDS----AIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESL 1180
            + + +   DC  F       S I  G+++E   AV   R   G C   I   G  HHA + EASGFC  N++ + A    L Y   ++L VD D+HHG+  Q  FY T +V+ +S H+Y + +F+P   +  Y+ +G + GR Y++N+PL +  + + +Y S+F  +I  +   Y P  +++  G DS     +GC   S   H  C   M  K  +L    ++VL  GGY + ++
Sbjct:   86 MSDFNVGEDCPVFPGLFDFCS-IYTGASLE--GAV---RLNQGICDIAINWAGGLHHAKKCEASGFCYVNDI-VVAILELLKYHN-RVLYVDIDIHHGDGVQEAFYLTDRVMTVSFHKYGN-HFFPGTGDM-YE-VGVDNGRLYSVNVPL-RDGIDDQNYASLFKPVINMVIDHYQPTCIVLQCGADSLGCDRLGCFNLSTKGHGECVRFM--KTFNLP---MLVLGGGGYTIRNV 304          
BLAST of Histone deacetylase,putative vs. Ensembl Medaka
Match: hdac6 (histone deacetylase 6 [Source:NCBI gene;Acc:101163380])

HSP 1 Score: 739.954 bits (1909), Expect = 0.000e+0
Identity = 416/1087 (38.27%), Postives = 584/1087 (53.73%), Query Frame = 2
Query:  185 DEDLPAAQSNHGLYDNIELRINFPNKTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKENDQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMN--ERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIIN--FPINKSGIEAIRKTLEYQKPYWKCLKFYEPLVVTYTEISPNQTNPAALDNIV----QIDTNTLAESVRQLGIVEVTFQTEQSIEETLSQPRNDTFITEPNSSNPIIHLPPIVSSDNAVEVPATTSINSTTHATQNISANFLSVD-QSSGATPVSANVSRVINEGNSVGLVLQDIMNLSGVSN-SDIHHFLGLTSNDPLPERVYAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQVFCGRFVQAHMMQHFQNTRHAIVLSFVDLSSWCYECDSYVHNECLNHAKREAHIAKFGVPQP 3415
            DE+L +     GL      R      T  VY E    H N+W+  + E PDR+R   E +    LL  C+ +Q +    E +   H++ ++ L++ T+TMT  +L+ L  ++D V+    +     I+AGS ++++  V+    +NGF +IRPPGHHA  SE +GFC+FNNV IAA+YA   ++  ++LIVDWDVHHG   QY F     +LY SIHRYE  +FWP L ES+  ++G+    G NIN+P NK  M+++DY+S F  ++LP+AYE+ P+LVL+SAGFD+A G P+G M+V P CF  +TH LM LA GR+V++LEGGY +++  +     +  L G+A P L     P +S   +I   +  L+  W  L V +        +  + +   T  ++  P L                                  T  VYD RM  H+N  +R  HPE P+R   IF   +   L+ RC+ ++SRLA+++E+ + HS  +++ +       P   H   +EF SI+I+  S+ SA L+ G     ++ + + +  N  AI+RPPGHHAE+++P GFC FN  A+ A +A  K S  ++ ILI+DWDVHHGNGTQH F  + +VLYISLHRYDNG FFP S DG+P  VG     G+NVN+AW+   + DS+Y++AF  +VMPI+ EFNP LV+VSAGFDAA+GDPLGG  VTPE + + T ML SLA G+V+  LEGGYNL  ISD M+ C S LLG P   +     P +     AI K +++  PYWK L+   P  V     SP           V    Q     L  S+ Q G+            E L Q      I++           P   S +AV +   +   S  H+        L  D QS  A P      + + E      + +D   L G    +      GL   +     +Y V PL WC HL  V+  P +  IDV+  C  C S  ENW+CLTCYQVFCGR+V  HM+ H +   H +VLSF DLS WCY C+SY+H++ L  AK  AH +KFG   P
Sbjct:   55 DEELSSIMGALGLSGRSAAR-----GTGLVYSEIFTRHQNLWEPSHPESPDRVRSIMEELERQQLLPCCVSVQPRAATEEELLLVHTKDYIDLVKSTETMTQSELQTLCCKYDSVYLHPLSFKVCAIAAGSVLQLVDEVMAFNLRNGFAVIRPPGHHAQTSEPNGFCVFNNVAIAARYACSRHAVSRVLIVDWDVHHGQGLQYLFQEDPSILYFSIHRYEHASFWPHLPESDSSFVGSGHAIGRNINLPWNKIGMSDADYISAFQHVLLPVAYEFQPQLVLVSAGFDAAAGDPKGEMNVSPQCFHTLTHMLMSLAEGRLVLVLEGGYNLKATAEGAAACVRALLGRACPPLNPPTGPSESAMHSISQTISALYVHWAFLQV-LEGTSSAEADSTKTVSGHTSTTTVAPALAAA-----------------------------TITGLVYDERMMEHVNLWDRH-HPEQPQRIFKIFSRHQQLGLVDRCQLIQSRLATEEELAMCHSLQHIQQMSATATMKPRDLHRLGDEFVSIFISNQSFQSAQLAAGSCFAAVEHMLNGQVNNAVAIVRPPGHHAEMDFPCGFCLFNTTALTARHA-QKVSHDLQ-ILILDWDVHHGNGTQHIFEDDNSVLYISLHRYDNGAFFPSSKDGAPENVGVAKGAGYNVNLAWSGGRMGDSDYLAAFHQVVMPIATEFNPGLVLVSAGFDAAQGDPLGGYHVTPEGYAHFTHMLMSLAGGRVLFILEGGYNLKSISDSMAACTSVLLGDPPPSLATPLPPPHHCAAVAINKVIQHHAPYWKSLRVQIPESVRAFLPSPKHRGKHGPKGRVRKSEQNSMGRLESSIVQSGL------------EQLMQGLAGLDISQ----------SPANQSLSAVSLSVRS--ESDPHSDTVEEMRVLKGDSQSRIALP------QTVAEVTPEMAIPKDKPQLEGACGWAGCQKDTGLMCAE--ETSLYVVDPLPWCSHLGSVKPLPPSG-IDVSRPCQDCGSEAENWICLTCYQVFCGRYVNEHMVAHGKEVEHPMVLSFSDLSVWCYMCESYIHHQVLFQAKNAAHFSKFGEESP 1070          
BLAST of Histone deacetylase,putative vs. Ensembl Medaka
Match: hdac10 (histone deacetylase 10 [Source:NCBI gene;Acc:101158373])

HSP 1 Score: 327.02 bits (837), Expect = 1.287e-97
Identity = 158/349 (45.27%), Postives = 222/349 (63.61%), Query Frame = 2
Query:  263 TAFVYDEQMLLHSNMWDN--LYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLH 1303
            TA +YDE+M  +  +W +     E P+RL V +  +    L + CI +  +E  +  I   HS+ +++ ++ T  MT   LKE + Q+  V+F  N    + ++ GS ++++ +VL  + KNG  L+RPPGHH+M S A+GFC+FNNV IAA+YA+  Y  ++ILIVDWD+HHG   QY F +   VLY S HRYE   FWP L++S+YD +G  EG G+NIN+P NK  M NSDYLS+F  ++LPIAYE+ P+LVL+ AGFDSAIG  EG M   P  FAH+T+ LM+LA G++  +LEGGY + SL  SV  T+ TL G   P L     PC S  E++Q C++  H
Sbjct:    3 TALIYDEEMTKYKLLWVDPACKIEVPERLTVSHGALVRNGLTDRCICLPVREAVDAEILLVHSEEYLEAVKQTPHMTLEDLKEFTLQYGDVYFHPNIYHCAKLAVGSALQLVDSVLMGKVKNGMALVRPPGHHSMRSAANGFCVFNNVAIAAQYAKQKYGVKRILIVDWDIHHGQGVQYCFEDDPSVLYFSWHRYEHQKFWPNLKDSDYDIVGKGEGAGFNINVPWNKVGMENSDYLSVFCHVLLPIAYEFCPDLVLVCAGFDSAIGDLEGEMCATPDIFAHLTYLLMNLAEGKLCAVLEGGYNLTSLAQSVCQTVQTLLGDPLPPLTNLTGPCRSTLESLQ-CVRAAH 350          

HSP 2 Score: 257.684 bits (657), Expect = 5.503e-73
Identity = 136/358 (37.99%), Postives = 204/358 (56.98%), Query Frame = 2
Query: 1517 TCFVYDCRMENH---MNERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINFP-INKSGIEAIRKTLEYQKPYWKCLK 2578
            T  +YD  M  +     + +   E P R  +    L  N L  RC  L  R A   EI L+HS  Y+E++      +      F  ++  +Y + + Y  A L+ G  L ++D V   + +NG A++RPPGHH+  +   GFC FNNVAIAA YA  KY   +K+ILIVDWD+HHG G Q+ F  + +VLY S HRY++  F+P   D     VG  +  GFN+N+ WNK  + +S+Y+S F ++++PI++EF PDLV+V AGFD+A GD  G +  TP+ F ++T +L +LA GK+   LEGGYNL  ++  +   V +LLG P   + N     +S +E+++      + +W CL+
Sbjct:    3 TALIYDEEMTKYKLLWVDPACKIEVPERLTVSHGALVRNGLTDRCICLPVREAVDAEILLVHSEEYLEAVKQTPHMTLEDLKEFTLQYGDVYFHPNIYHCAKLAVGSALQLVDSVLMGKVKNGMALVRPPGHHSMRSAANGFCVFNNVAIAAQYAKQKYG--VKRILIVDWDIHHGQGVQYCFEDDPSVLYFSWHRYEHQKFWPNLKDSDYDIVGKGEGAGFNINVPWNKVGMENSDYLSVFCHVLLPIAYEFCPDLVLVCAGFDSAIGDLEGEMCATPDIFAHLTYLLMNLAEGKLCAVLEGGYNLTSLAQSVCQTVQTLLGDPLPPLTNLTGPCRSTLESLQCVRAAHRQHWSCLR 358          
BLAST of Histone deacetylase,putative vs. Ensembl Medaka
Match: hdac10 (histone deacetylase 10 [Source:NCBI gene;Acc:101158373])

HSP 1 Score: 326.635 bits (836), Expect = 1.431e-97
Identity = 158/349 (45.27%), Postives = 222/349 (63.61%), Query Frame = 2
Query:  263 TAFVYDEQMLLHSNMWDN--LYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLH 1303
            TA +YDE+M  +  +W +     E P+RL V +  +    L + CI +  +E  +  I   HS+ +++ ++ T  MT   LKE + Q+  V+F  N    + ++ GS ++++ +VL  + KNG  L+RPPGHH+M S A+GFC+FNNV IAA+YA+  Y  ++ILIVDWD+HHG   QY F +   VLY S HRYE   FWP L++S+YD +G  EG G+NIN+P NK  M NSDYLS+F  ++LPIAYE+ P+LVL+ AGFDSAIG  EG M   P  FAH+T+ LM+LA G++  +LEGGY + SL  SV  T+ TL G   P L     PC S  E++Q C++  H
Sbjct:    3 TALIYDEEMTKYKLLWVDPACKIEVPERLTVSHGALVRNGLTDRCICLPVREAVDAEILLVHSEEYLEAVKQTPHMTLEDLKEFTLQYGDVYFHPNIYHCAKLAVGSALQLVDSVLMGKVKNGMALVRPPGHHSMRSAANGFCVFNNVAIAAQYAKQKYGVKRILIVDWDIHHGQGVQYCFEDDPSVLYFSWHRYEHQKFWPNLKDSDYDIVGKGEGAGFNINVPWNKVGMENSDYLSVFCHVLLPIAYEFCPDLVLVCAGFDSAIGDLEGEMCATPDIFAHLTYLLMNLAEGKLCAVLEGGYNLTSLAQSVCQTVQTLLGDPLPPLTNLTGPCRSTLESLQ-CVRAAH 350          

HSP 2 Score: 258.07 bits (658), Expect = 4.826e-73
Identity = 136/358 (37.99%), Postives = 204/358 (56.98%), Query Frame = 2
Query: 1517 TCFVYDCRMENH---MNERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINFP-INKSGIEAIRKTLEYQKPYWKCLK 2578
            T  +YD  M  +     + +   E P R  +    L  N L  RC  L  R A   EI L+HS  Y+E++      +      F  ++  +Y + + Y  A L+ G  L ++D V   + +NG A++RPPGHH+  +   GFC FNNVAIAA YA  KY   +K+ILIVDWD+HHG G Q+ F  + +VLY S HRY++  F+P   D     VG  +  GFN+N+ WNK  + +S+Y+S F ++++PI++EF PDLV+V AGFD+A GD  G +  TP+ F ++T +L +LA GK+   LEGGYNL  ++  +   V +LLG P   + N     +S +E+++      + +W CL+
Sbjct:    3 TALIYDEEMTKYKLLWVDPACKIEVPERLTVSHGALVRNGLTDRCICLPVREAVDAEILLVHSEEYLEAVKQTPHMTLEDLKEFTLQYGDVYFHPNIYHCAKLAVGSALQLVDSVLMGKVKNGMALVRPPGHHSMRSAANGFCVFNNVAIAAQYAKQKYG--VKRILIVDWDIHHGQGVQYCFEDDPSVLYFSWHRYEHQKFWPNLKDSDYDIVGKGEGAGFNINVPWNKVGMENSDYLSVFCHVLLPIAYEFCPDLVLVCAGFDSAIGDLEGEMCATPDIFAHLTYLLMNLAEGKLCAVLEGGYNLTSLAQSVCQTVQTLLGDPLPPLTNLTGPCRSTLESLQCVRAAHRQHWSCLR 358          
BLAST of Histone deacetylase,putative vs. Ensembl Medaka
Match: hdac10 (histone deacetylase 10 [Source:NCBI gene;Acc:101158373])

HSP 1 Score: 315.849 bits (808), Expect = 2.528e-93
Identity = 151/327 (46.18%), Postives = 210/327 (64.22%), Query Frame = 2
Query:  323 FERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLH 1303
             E P+RL V +  +    L + CI +  +E  +  I   HS+ +++ ++ T  MT   LKE + Q+  V+F  N    + ++ GS ++++ +VL  + KNG  L+RPPGHH+M S A+GFC+FNNV IAA+YA+  Y  ++ILIVDWD+HHG   QY F +   VLY S HRYE   FWP L++S+YD +G  EG G+NIN+P NK  M NSDYLS+F  ++LPIAYE+ P+LVL+ AGFDSAIG  EG M   P  FAH+T+ LM+LA G++  +LEGGY + SL  SV  T+ TL G   P L     PC S  E++Q C++  H
Sbjct:   56 IEVPERLTVSHGALVRNGLTDRCICLPVREAVDAEILLVHSEEYLEAVKQTPHMTLEDLKEFTLQYGDVYFHPNIYHCAKLAVGSALQLVDSVLMGKVKNGMALVRPPGHHSMRSAANGFCVFNNVAIAAQYAKQKYGVKRILIVDWDIHHGQGVQYCFEDDPSVLYFSWHRYEHQKFWPNLKDSDYDIVGKGEGAGFNINVPWNKVGMENSDYLSVFCHVLLPIAYEFCPDLVLVCAGFDSAIGDLEGEMCATPDIFAHLTYLLMNLAEGKLCAVLEGGYNLTSLAQSVCQTVQTLLGDPLPPLTNLTGPCRSTLESLQ-CVRAAH 381          

HSP 2 Score: 256.914 bits (655), Expect = 2.113e-72
Identity = 133/336 (39.58%), Postives = 197/336 (58.63%), Query Frame = 2
Query: 1577 ESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINF--PINKSGIEAIRKTLEYQKPYWKCLK 2578
            E P R  +    L  N L  RC  L  R A   EI L+HS  Y+E++      +      F  ++  +Y + + Y  A L+ G  L ++D V   + +NG A++RPPGHH+  +   GFC FNNVAIAA YA  KY   +K+ILIVDWD+HHG G Q+ F  + +VLY S HRY++  F+P   D     VG  +  GFN+N+ WNK  + +S+Y+S F ++++PI++EF PDLV+V AGFD+A GD  G +  TP+ F ++T +L +LA GK+   LEGGYNL  ++  +   V +LLG P   + N   P  +S +E+++      + +W CL+
Sbjct:   57 EVPERLTVSHGALVRNGLTDRCICLPVREAVDAEILLVHSEEYLEAVKQTPHMTLEDLKEFTLQYGDVYFHPNIYHCAKLAVGSALQLVDSVLMGKVKNGMALVRPPGHHSMRSAANGFCVFNNVAIAAQYAKQKYG--VKRILIVDWDIHHGQGVQYCFEDDPSVLYFSWHRYEHQKFWPNLKDSDYDIVGKGEGAGFNINVPWNKVGMENSDYLSVFCHVLLPIAYEFCPDLVLVCAGFDSAIGDLEGEMCATPDIFAHLTYLLMNLAEGKLCAVLEGGYNLTSLAQSVCQTVQTLLGDPLPPLTNLTGPC-RSTLESLQCVRAAHRQHWSCLR 389          
BLAST of Histone deacetylase,putative vs. Ensembl Medaka
Match: hdac7a (histone deacetylase 7 [Source:NCBI gene;Acc:101159670])

HSP 1 Score: 307.375 bits (786), Expect = 2.286e-88
Identity = 174/465 (37.42%), Postives = 263/465 (56.56%), Query Frame = 2
Query: 1280 QNCLKFLHFFWKSLSVNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKENDQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHM---NERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYV-----ESLGNICQESPTIYHLFEEEF-------------NSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKR---PVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGD--PLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLG----YPTNQIINFPINKSGIEAIRKTLEYQKPYWKCLKFY 2584
            Q  L+ LH   K+L+V V          +      T +S     L + + P        LN    E+ +K  F      T  VYD +M  H     + S HPE   R Q I+  L++  L  +C+ +  R A+ +E+  +H+  +V       L  +  ++  +  +F +               ++I+   H+  ++ ++ G ++ +   V     +NGFA++RPPGHHA+ + P+GFC+FN+VAIAA     K S  + KILIVDWDVHHGNGTQ  F+ +++VLYISLHRYD+G FFPGS  GSP+ VG    EGFNVN+AW      P+ D+EY++AF ++VMPI+ EF+PD+V+VSAGFDAA G+  PLGG  V+ +CFG +T  L SLA G++ILALEGG++L  I D    CVS+LLG     P + ++  P N + + +++  ++ Q  +W+ +K +
Sbjct:  423 QKQLQQLHRQMKTLAVPVLPGGCSGGGGIHRPLSRTQSSPASTSLTLPEKP--------LNLAAPEISSKPRFT-----TGLVYDSQMLKHQCACGDNSSHPEHAGRIQSIWSRLQERGLRGQCESIRGRKATLEELQSVHTERHVLLYGTNPLNRLKLDNRKLAGIFSQRMFTMLPCGGVGVDNDTIWNESHTSTASRMAAGSVVELAFRVAKGELKNGFAVVRPPGHHADPSNPMGFCYFNSVAIAAKQLQQKLS--VSKILIVDWDVHHGNGTQEVFYNDRSVLYISLHRYDDGNFFPGS--GSPAEVGSGAGEGFNVNLAWTGGLDPPMGDAEYLAAFRSVVMPIAQEFSPDVVLVSAGFDAAEGNPAPLGGYKVSAKCFGFLTHQLMSLAGGRLILALEGGHDLTAICDASEACVSALLGMQDSMPEDVLLQKP-NANAVRSLQTVIQIQSQFWQNVKAH 869          

HSP 2 Score: 242.662 bits (618), Expect = 3.271e-66
Identity = 136/383 (35.51%), Postives = 209/383 (54.57%), Query Frame = 2
Query:  263 TAFVYDEQMLLHS-NMWDNL-YFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQL------------------IEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLN---KTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIG--CPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTG--KAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVN 1330
            T  VYD QML H     DN  + E   R++  +  + E  L   C  I+ ++   E +   H++ HV L                  I   +  T +    +   +D ++ +++T  AS ++AGS +E+   V     KNGF ++RPPGHHA  S   GFC FN+V IAAK  Q   S  KILIVDWDVHHGN TQ  FYN   VLYIS+HRY+DGNF+P     +   +G+  G G+N+N+         M +++YL+ F S+++PIA E++P++VL+SAGFD+A G   P G   V   CF  +TH+LM LA GR+++ LEGG+ + ++ D+    ++ L G   + P+     +P  +   ++Q  ++    FW+++  +
Sbjct:  489 TGLVYDSQMLKHQCACGDNSSHPEHAGRIQSIWSRLQERGLRGQCESIRGRKATLEELQSVHTERHVLLYGTNPLNRLKLDNRKLAGIFSQRMFTMLPCGGVGVDNDTIWNESHTSTASRMAAGSVVELAFRVAKGELKNGFAVVRPPGHHADPSNPMGFCYFNSVAIAAKQLQQKLSVSKILIVDWDVHHGNGTQEVFYNDRSVLYISLHRYDDGNFFPG--SGSPAEVGSGAGEGFNVNLAWTGGLDPPMGDAEYLAAFRSVVMPIAQEFSPDVVLVSAGFDAAEGNPAPLGGYKVSAKCFGFLTHQLMSLAGGRLILALEGGHDLTAICDASEACVSALLGMQDSMPEDVLLQKPNANAVRSLQTVIQIQSQFWQNVKAH 869          
BLAST of Histone deacetylase,putative vs. Planmine SMEST
Match: SMESG000006246.1 (SMESG000006246.1)

HSP 1 Score: 2098.94 bits (5437), Expect = 0.000e+0
Identity = 1011/1019 (99.21%), Postives = 1014/1019 (99.51%), Query Frame = 2
Query:  179 FGDEDLPAAQSNHGLYDNIELRINFPNKTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKENDQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMNERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINFPINKSGIEAIRKTLEYQKPYWKCLKFYEPLVVTYTEISPNQTNPAALDNIVQIDTNTLAESVRQLGIVEVTFQTEQSIEETLSQPRNDTFITEPNSSNPIIHLPPIVSSDNAVEVPATT-SINSTTHATQNISANFLSVDQSSGATPVSANVSRVINEGNSVGLVLQDIMNLSGVSNSDIHHFLGLTSNDPLPERVYAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQV 3232
            FGDEDLPAAQSNHGLYDNIELRINFPNKTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLE FDEPCDSVKETIQNCLKFLHF+WKSLSVNVADNHEPYPEY+RHLPESTWNSSKVPKLPIEDNPNKCKE DQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMNERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGG DAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINFPINKSGIEAIRKTLEYQKPYWKCLKFYEPLVVTYTEISPNQTNPAALDNIVQI+TNTLAESVRQLGIVEVTFQTEQSIEETLSQPRNDTFITEPNSSNPIIHLPPIVSSDNAVEVP TT SINSTTHATQNISANFLSVDQSSGATPVSANVSRVINEGNSVGLVLQDIMNLSGVSNSDIHHFLGLTSNDPLPERVYAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQV
Sbjct:   24 FGDEDLPAAQSNHGLYDNIELRINFPNKTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLENFDEPCDSVKETIQNCLKFLHFYWKSLSVNVADNHEPYPEYMRHLPESTWNSSKVPKLPIEDNPNKCKEKDQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMNERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGVDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINFPINKSGIEAIRKTLEYQKPYWKCLKFYEPLVVTYTEISPNQTNPAALDNIVQIETNTLAESVRQLGIVEVTFQTEQSIEETLSQPRNDTFITEPNSSNPIIHLPPIVSSDNAVEVPPTTSSINSTTHATQNISANFLSVDQSSGATPVSANVSRVINEGNSVGLVLQDIMNLSGVSNSDIHHFLGLTSNDPLPERVYAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQV 1042          
BLAST of Histone deacetylase,putative vs. Planmine SMEST
Match: SMESG000006246.1 (SMESG000006246.1)

HSP 1 Score: 2098.55 bits (5436), Expect = 0.000e+0
Identity = 1011/1019 (99.21%), Postives = 1014/1019 (99.51%), Query Frame = 2
Query:  179 FGDEDLPAAQSNHGLYDNIELRINFPNKTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKENDQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMNERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINFPINKSGIEAIRKTLEYQKPYWKCLKFYEPLVVTYTEISPNQTNPAALDNIVQIDTNTLAESVRQLGIVEVTFQTEQSIEETLSQPRNDTFITEPNSSNPIIHLPPIVSSDNAVEVPATT-SINSTTHATQNISANFLSVDQSSGATPVSANVSRVINEGNSVGLVLQDIMNLSGVSNSDIHHFLGLTSNDPLPERVYAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQV 3232
            FGDEDLPAAQSNHGLYDNIELRINFPNKTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLE FDEPCDSVKETIQNCLKFLHF+WKSLSVNVADNHEPYPEY+RHLPESTWNSSKVPKLPIEDNPNKCKE DQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMNERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGG DAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINFPINKSGIEAIRKTLEYQKPYWKCLKFYEPLVVTYTEISPNQTNPAALDNIVQI+TNTLAESVRQLGIVEVTFQTEQSIEETLSQPRNDTFITEPNSSNPIIHLPPIVSSDNAVEVP TT SINSTTHATQNISANFLSVDQSSGATPVSANVSRVINEGNSVGLVLQDIMNLSGVSNSDIHHFLGLTSNDPLPERVYAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQV
Sbjct:   26 FGDEDLPAAQSNHGLYDNIELRINFPNKTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLENFDEPCDSVKETIQNCLKFLHFYWKSLSVNVADNHEPYPEYMRHLPESTWNSSKVPKLPIEDNPNKCKEKDQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMNERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGVDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINFPINKSGIEAIRKTLEYQKPYWKCLKFYEPLVVTYTEISPNQTNPAALDNIVQIETNTLAESVRQLGIVEVTFQTEQSIEETLSQPRNDTFITEPNSSNPIIHLPPIVSSDNAVEVPPTTSSINSTTHATQNISANFLSVDQSSGATPVSANVSRVINEGNSVGLVLQDIMNLSGVSNSDIHHFLGLTSNDPLPERVYAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQV 1044          
BLAST of Histone deacetylase,putative vs. Planmine SMEST
Match: SMESG000028609.1 (SMESG000028609.1)

HSP 1 Score: 284.648 bits (727), Expect = 9.446e-80
Identity = 171/495 (34.55%), Postives = 265/495 (53.54%), Query Frame = 2
Query: 1505 YPNKTCFVYDCRMENHM---NERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLG----NICQESPTIYHLFEEEF------------NSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRP------VRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAAR--GDPLGGLTVTPECFGNMTQML--TSLANGKVILALEGGYNLNVISDCMSHCVSSL----------------------LGYPTNQIINFPINKSGIEAIRKTLEYQKPYWKCLKFYEPLVVTYTEISPNQTNPAALDNIVQIDTNTLAESVRQLGIVEVTFQTEQSIEETLSQPRNDTFITEPNSSNPIIHLPPIVSSDN 2836
            YPN T  VYD  M +H        IHPES RR  M++E L+++ ++ RC  ++ + AS D++ L H   Y    G    N  + +P +  L   EF            ++I+ N H+  +A L+ G ++ +  ++      NGFA++RPPGHHAE +  +GF +FN+VAIAA     +   ++K++LI+DWD+HHGNGTQ  F+ + +VLYISLHR+DNG FFPG+  G    +G      +N+NIAW   P      + D+EYI+AF++IV+P++ EFNPDL+IVSAGFDA +     LGG +V+P CFG MTQ L  + LA G+V++ALEGGY++  + DC+  C+ +L                      +  P++++   P + + IE +    +  K  W+C +F     + Y          +  D + ++  +   +S+  L + E+T Q E S  E    P+           +PIIH  P+    N
Sbjct:  567 YPNTTAIVYDVGMLSHRCLCGNEDIHPESSRRLAMVWERLKESQIVLRCHVIQGKKASMDDLQLCHEDTYSVLFGTNPANRLKINPQL--LMSVEFCRLPCGGIGVDSDTIWNNAHTANAARLAVGCVVELTLKIVRGELRNGFALVRPPGHHAEFSQAMGFGYFNSVAIAAKKITMQ--TAVKRVLIIDWDIHHGNGTQQIFYNDPSVLYISLHRHDNGHFFPGT--GLIEEIGEGAGTNYNINIAWKSPPDGSFLSMSDAEYIAAFVHIVLPVAKEFNPDLIIVSAGFDATKMHSSSLGGYSVSPACFGWMTQKLVMSGLAEGRVVMALEGGYDIASLCDCVEVCMRALIKPDVLNFTESGTRPLKDAEGKMTIPSSELNRVPCDIA-IETLFTVSQTHKKKWQCFRFLTKESIKY----------SYNDLVKKLLGSKSYDSIPLLAMSELTVQHEHSKHE----PKQVIDYEMICVKSPIIHSEPMEQESN 1040          

HSP 2 Score: 220.32 bits (560), Expect = 1.933e-58
Identity = 125/349 (35.82%), Postives = 196/349 (56.16%), Query Frame = 2
Query:  245 INFPNKTAFVYDEQMLLHSNMWDN--LYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHV---------QLIEDTQTMTAIQLKEL-----SSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKT------NMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAI--GCPEGSMDVHPACFAHMTHKLM--DLARGRVVVLLEGGYCMESLKDSVVLTLATL 1213
            + +PN TA VYD  ML H  +  N  ++ E   RL + +E + E+ ++  C  IQ K+   + +   H  ++          +L  + Q + +++   L         D ++ + +T  A+ ++ G  +E+   ++    +NGF L+RPPGHHA  S+A GF  FN+V IAAK   +  + +++LI+DWD+HHGN TQ  FYN   VLYIS+HR+++G+F+P       + IG   G  YNINI           +M++++Y++ F  I+LP+A E+NP+L+++SAGFD+        G   V PACF  MT KL+   LA GRVV+ LEGGY + SL D V + +  L
Sbjct:  565 LEYPNTTAIVYDVGMLSHRCLCGNEDIHPESSRRLAMVWERLKESQIVLRCHVIQGKKASMDDLQLCHEDTYSVLFGTNPANRLKINPQLLMSVEFCRLPCGGIGVDSDTIWNNAHTANAARLAVGCVVELTLKIVRGELRNGFALVRPPGHHAEFSQAMGFGYFNSVAIAAKKITMQTAVKRVLIIDWDIHHGNGTQQIFYNDPSVLYISLHRHDNGHFFPG--TGLIEEIGEGAGTNYNINIAWKSPPDGSFLSMSDAEYIAAFVHIVLPVAKEFNPDLIIVSAGFDATKMHSSSLGGYSVSPACFGWMTQKLVMSGLAEGRVVMALEGGYDIASLCDCVEVCMRAL 911          
BLAST of Histone deacetylase,putative vs. Planmine SMEST
Match: SMESG000028609.1 (SMESG000028609.1)

HSP 1 Score: 284.263 bits (726), Expect = 2.278e-79
Identity = 171/495 (34.55%), Postives = 265/495 (53.54%), Query Frame = 2
Query: 1505 YPNKTCFVYDCRMENHM---NERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLG----NICQESPTIYHLFEEEF------------NSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRP------VRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAAR--GDPLGGLTVTPECFGNMTQML--TSLANGKVILALEGGYNLNVISDCMSHCVSSL----------------------LGYPTNQIINFPINKSGIEAIRKTLEYQKPYWKCLKFYEPLVVTYTEISPNQTNPAALDNIVQIDTNTLAESVRQLGIVEVTFQTEQSIEETLSQPRNDTFITEPNSSNPIIHLPPIVSSDN 2836
            YPN T  VYD  M +H        IHPES RR  M++E L+++ ++ RC  ++ + AS D++ L H   Y    G    N  + +P +  L   EF            ++I+ N H+  +A L+ G ++ +  ++      NGFA++RPPGHHAE +  +GF +FN+VAIAA     +   ++K++LI+DWD+HHGNGTQ  F+ + +VLYISLHR+DNG FFPG+  G    +G      +N+NIAW   P      + D+EYI+AF++IV+P++ EFNPDL+IVSAGFDA +     LGG +V+P CFG MTQ L  + LA G+V++ALEGGY++  + DC+  C+ +L                      +  P++++   P + + IE +    +  K  W+C +F     + Y          +  D + ++  +   +S+  L + E+T Q E S  E    P+           +PIIH  P+    N
Sbjct:  616 YPNTTAIVYDVGMLSHRCLCGNEDIHPESSRRLAMVWERLKESQIVLRCHVIQGKKASMDDLQLCHEDTYSVLFGTNPANRLKINPQL--LMSVEFCRLPCGGIGVDSDTIWNNAHTANAARLAVGCVVELTLKIVRGELRNGFALVRPPGHHAEFSQAMGFGYFNSVAIAAKKITMQ--TAVKRVLIIDWDIHHGNGTQQIFYNDPSVLYISLHRHDNGHFFPGT--GLIEEIGEGAGTNYNINIAWKSPPDGSFLSMSDAEYIAAFVHIVLPVAKEFNPDLIIVSAGFDATKMHSSSLGGYSVSPACFGWMTQKLVMSGLAEGRVVMALEGGYDIASLCDCVEVCMRALIKPDVLNFTESGTRPLKDAEGKMTIPSSELNRVPCDIA-IETLFTVSQTHKKKWQCFRFLTKESIKY----------SYNDLVKKLLGSKSYDSIPLLAMSELTVQHEHSKHE----PKQVIDYEMICVKSPIIHSEPMEQESN 1089          

HSP 2 Score: 219.935 bits (559), Expect = 3.200e-58
Identity = 125/349 (35.82%), Postives = 195/349 (55.87%), Query Frame = 2
Query:  245 INFPNKTAFVYDEQMLLHSNMWDN--LYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIE---------DTQTMTAIQLKEL-----SSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKT------NMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAI--GCPEGSMDVHPACFAHMTHKLM--DLARGRVVVLLEGGYCMESLKDSVVLTLATL 1213
            + +PN TA VYD  ML H  +  N  ++ E   RL + +E + E+ ++  C  IQ K+   + +   H  ++  L           + Q + +++   L         D ++ + +T  A+ ++ G  +E+   ++    +NGF L+RPPGHHA  S+A GF  FN+V IAAK   +  + +++LI+DWD+HHGN TQ  FYN   VLYIS+HR+++G+F+P       + IG   G  YNINI           +M++++Y++ F  I+LP+A E+NP+L+++SAGFD+        G   V PACF  MT KL+   LA GRVV+ LEGGY + SL D V + +  L
Sbjct:  614 LEYPNTTAIVYDVGMLSHRCLCGNEDIHPESSRRLAMVWERLKESQIVLRCHVIQGKKASMDDLQLCHEDTYSVLFGTNPANRLKINPQLLMSVEFCRLPCGGIGVDSDTIWNNAHTANAARLAVGCVVELTLKIVRGELRNGFALVRPPGHHAEFSQAMGFGYFNSVAIAAKKITMQTAVKRVLIIDWDIHHGNGTQQIFYNDPSVLYISLHRHDNGHFFPG--TGLIEEIGEGAGTNYNINIAWKSPPDGSFLSMSDAEYIAAFVHIVLPVAKEFNPDLIIVSAGFDATKMHSSSLGGYSVSPACFGWMTQKLVMSGLAEGRVVMALEGGYDIASLCDCVEVCMRAL 960          
BLAST of Histone deacetylase,putative vs. Planmine SMEST
Match: SMESG000060876.1 (SMESG000060876.1)

HSP 1 Score: 112.849 bits (281), Expect = 8.763e-26
Identity = 82/326 (25.15%), Postives = 150/326 (46.01%), Query Frame = 2
Query: 1514 KTCFVYDCRMENHMNERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCS----DRSENGFAIIRPPG-HHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLG 2476
            K C+ YD  + N+   +  HP  P R +M    L +  L  + +  +   A+ D++ + H+  Y++ L  I    P   H + +E     + +   +   L     L+    V S    ++++   AI    G HHA+ +   GFC+ N++ +     L KY E   ++L VD D+HHG+G +  F+T   V+ +S H+Y  G +FPG+  G    +G    + + VN    +  + D  Y S F  +V  +   F P+ +++  G D+  GD LG   ++ +  G   + +       ++L   GGY +  ++ C ++  +  LG
Sbjct:    8 KVCYYYDGDIGNYYYGQG-HPMKPHRIRMTHNLLLNYGLYRKMEVYKPSKATADDMTMFHTDEYIQFLQRI---HPDNMHEYNKEMQRFNVGEDCPVFDGLFEFCQLSAGGSVASAVKLNKNKADIAINWSGGLHHAKKSEASGFCYVNDIVMGI-LELLKYHE---RVLYVDIDIHHGDGVEEAFYTTDRVMTVSFHKY--GEYFPGT--GDIKDIGAGKGKNYAVNFPL-RDGIDDESYESIFKPVVEKVIESFKPNAIVLQCGADSLSGDRLGCFNLSLKGHGKCVEYMRQQPIPLLMLG-GGGYTIRNVARCWTYETALALG 319          

HSP 2 Score: 103.99 bits (258), Expect = 7.974e-23
Identity = 77/310 (24.84%), Postives = 140/310 (45.16%), Query Frame = 2
Query:  329 RPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIE----DTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPG-HHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDS----AIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPP 1231
            +P R+R+ +  +    L       +  +   + +   H+  ++Q ++    D       +++  +   DC  FD   +     + GS   V  AV  ++ K    +    G HHA +SEASGFC  N++ +      L Y  +++L VD D+HHG+  +  FY T +V+ +S H+Y  G ++P     +   IGA +G+ Y +N PL +  + +  Y SIF  ++  +   + P  +++  G DS     +GC   S+  H  C  +M  + + L     ++L  GGY + ++        A   G   P
Sbjct:   29 KPHRIRMTHNLLLNYGLYRKMEVYKPSKATADDMTMFHTDEYIQFLQRIHPDNMHEYNKEMQRFNVGEDCPVFDGLFEFCQLSAGGS---VASAVKLNKNKADIAINWSGGLHHAKKSEASGFCYVNDI-VMGILELLKYH-ERVLYVDIDIHHGDGVEEAFYTTDRVMTVSFHKY--GEYFPGT--GDIKDIGAGKGKNYAVNFPL-RDGIDDESYESIFKPVVEKVIESFKPNAIVLQCGADSLSGDRLGCFNLSLKGHGKCVEYMRQQPIPL-----LMLGGGGYTIRNVARCWTYETALALGTTIP 323          
The following BLAST results are available for this feature:
BLAST of Histone deacetylase,putative vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
HDAC68.515e-7440.54histone deacetylase 6 [Source:HGNC Symbol;Acc:HGNC... [more]
HDAC68.515e-7440.54histone deacetylase 6 [Source:HGNC Symbol;Acc:HGNC... [more]
HDAC68.515e-7440.54histone deacetylase 6 [Source:HGNC Symbol;Acc:HGNC... [more]
HDAC68.515e-7440.54histone deacetylase 6 [Source:HGNC Symbol;Acc:HGNC... [more]
HDAC68.732e-7440.54histone deacetylase 6 [Source:HGNC Symbol;Acc:HGNC... [more]
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BLAST of Histone deacetylase,putative vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
hda-64.323e-15536.22Histone deacetylase 6 [Source:UniProtKB/Swiss-Pro... [more]
hda-64.323e-15536.22Histone deacetylase 6 [Source:UniProtKB/Swiss-Pro... [more]
hda-63.100e-15336.15Histone deacetylase 6 [Source:UniProtKB/Swiss-Pro... [more]
hda-63.100e-15336.15Histone deacetylase 6 [Source:UniProtKB/Swiss-Pro... [more]
hda-62.464e-15236.40Histone deacetylase 6 [Source:UniProtKB/Swiss-Pro... [more]
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BLAST of Histone deacetylase,putative vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
HDAC61.572e-7941.95gene:FBgn0026428 transcript:FBtr0307384[more]
HDAC64.291e-8041.95gene:FBgn0026428 transcript:FBtr0301774[more]
HDAC66.952e-7941.95gene:FBgn0026428 transcript:FBtr0074009[more]
HDAC65.543e-7941.95gene:FBgn0026428 transcript:FBtr0074008[more]
HDAC67.015e-7941.95gene:FBgn0026428 transcript:FBtr0074010[more]
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BLAST of Histone deacetylase,putative vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
hdac61.151e-9437.93histone deacetylase 6 [Source:ZFIN;Acc:ZDB-GENE-03... [more]
hdac61.151e-9437.93histone deacetylase 6 [Source:ZFIN;Acc:ZDB-GENE-03... [more]
hdac105.148e-9941.73histone deacetylase 10 [Source:NCBI gene;Acc:32725... [more]
hdac42.207e-8542.59histone deacetylase 4 [Source:ZFIN;Acc:ZDB-GENE-06... [more]
hdac44.552e-8542.59histone deacetylase 4 [Source:ZFIN;Acc:ZDB-GENE-06... [more]
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BLAST of Histone deacetylase,putative vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
gpr1071.557e-9041.72G protein-coupled receptor 107 [Source:Xenbase;Acc... [more]
ENSXETT00000022901.13.475e-10744.93histone deacetylase 10 [Source:NCBI gene;Acc:10049... [more]
ENSXETT00000022890.17.979e-10744.93histone deacetylase 10 [Source:NCBI gene;Acc:10049... [more]
ENSXETT00000036079.11.525e-10544.69histone deacetylase 10 [Source:NCBI gene;Acc:10049... [more]
ENSXETT00000022845.11.369e-10144.48histone deacetylase 10 [Source:NCBI gene;Acc:10049... [more]
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BLAST of Histone deacetylase,putative vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Hdac60.000e+037.04histone deacetylase 6 [Source:MGI Symbol;Acc:MGI:1... [more]
Hdac60.000e+037.04histone deacetylase 6 [Source:MGI Symbol;Acc:MGI:1... [more]
Hdac65.879e-8540.61histone deacetylase 6 [Source:MGI Symbol;Acc:MGI:1... [more]
Hdac105.962e-10344.36histone deacetylase 10 [Source:MGI Symbol;Acc:MGI:... [more]
Hdac93.534e-8541.56histone deacetylase 9 [Source:MGI Symbol;Acc:MGI:1... [more]
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BLAST of Histone deacetylase,putative vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q9Z2V5|HDAC6_MOUSE0.000e+037.04Histone deacetylase 6 OS=Mus musculus OX=10090 GN=... [more]
sp|Q9UBN7|HDAC6_HUMAN4.089e-7340.54Histone deacetylase 6 OS=Homo sapiens OX=9606 GN=H... [more]
sp|Q20296|HDA6_CAEEL3.943e-15236.15Histone deacetylase 6 OS=Caenorhabditis elegans OX... [more]
sp|Q6P3E7|HDA10_MOUSE4.170e-10244.36Polyamine deacetylase HDAC10 OS=Mus musculus OX=10... [more]
sp|Q969S8|HDA10_HUMAN1.497e-10144.79Polyamine deacetylase HDAC10 OS=Homo sapiens OX=96... [more]
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BLAST of Histone deacetylase,putative vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0X3PKU10.000e+041.95UBP-type domain-containing protein OS=Schistocepha... [more]
A0A210QHS90.000e+040.76Histone deacetylase 6 OS=Mizuhopecten yessoensis O... [more]
A0A1S3JEN45.272e-8740.20LOW QUALITY PROTEIN: histone deacetylase 6-like OS... [more]
A0A3Q0KMY10.000e+039.27Histone deacetylase,putative OS=Schistosoma manson... [more]
A0A158QH172.183e-9039.58UBP-type domain-containing protein OS=Rodentolepis... [more]
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BLAST of Histone deacetylase,putative vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
hdac60.000e+037.92histone deacetylase 6 [Source:ZFIN;Acc:ZDB-GENE-03... [more]
hdac63.349e-9038.51histone deacetylase 6 [Source:ZFIN;Acc:ZDB-GENE-03... [more]
hdac101.878e-10044.23histone deacetylase 10 [Source:NCBI gene;Acc:10302... [more]
hdac108.136e-10044.23histone deacetylase 10 [Source:NCBI gene;Acc:10302... [more]
hdac7a7.779e-8842.74histone deacetylase 7a [Source:ZFIN;Acc:ZDB-GENE-1... [more]
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BLAST of Histone deacetylase,putative vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
hdac63.029e-8339.44histone deacetylase 6 [Source:ZFIN;Acc:ZDB-GENE-03... [more]
ENSPMAT00000005422.11.273e-8239.33pep scaffold:Pmarinus_7.0:GL501185:343872:431549:1... [more]
hdac41.312e-6041.61histone deacetylase 4 [Source:ZFIN;Acc:ZDB-GENE-06... [more]
ENSPMAT00000001508.11.312e-3143.33pep scaffold:Pmarinus_7.0:GL487756:6232:7801:1 gen... [more]
hdac34.724e-2023.67histone deacetylase 3 [Source:NCBI gene;Acc:393965... [more]
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BLAST of Histone deacetylase,putative vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
HDA14.821e-8539.84Putative catalytic subunit of a class II histone d... [more]
HOS25.846e-2728.57Histone deacetylase and subunit of Set3 and Rpd3L ... [more]
RPD31.721e-2426.59Histone deacetylase, component of both the Rpd3S a... [more]
HOS31.574e-1325.27Trichostatin A-insensitive homodimeric histone dea... [more]
HOS14.005e-1230.43Class I histone deacetylase (HDAC) family member; ... [more]
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BLAST of Histone deacetylase,putative vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO333211.689e-9240.11Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO357563.358e-8040.17Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO325594.558e-2328.87Histone deacetylase [Source:UniProtKB/TrEMBL;Acc:... [more]
EDO499208.693e-2327.72Histone deacetylase [Source:UniProtKB/TrEMBL;Acc:... [more]
EDO390622.460e-2123.68Histone deacetylase [Source:UniProtKB/TrEMBL;Acc:... [more]
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BLAST of Histone deacetylase,putative vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
hdac60.000e+038.27histone deacetylase 6 [Source:NCBI gene;Acc:101163... [more]
hdac101.287e-9745.27histone deacetylase 10 [Source:NCBI gene;Acc:10115... [more]
hdac101.431e-9745.27histone deacetylase 10 [Source:NCBI gene;Acc:10115... [more]
hdac102.528e-9346.18histone deacetylase 10 [Source:NCBI gene;Acc:10115... [more]
hdac7a2.286e-8837.42histone deacetylase 7 [Source:NCBI gene;Acc:101159... [more]
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BLAST of Histone deacetylase,putative vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000006246.10.000e+099.21SMESG000006246.1[more]
SMESG000006246.10.000e+099.21SMESG000006246.1[more]
SMESG000028609.19.446e-8034.55SMESG000028609.1[more]
SMESG000028609.12.278e-7934.55SMESG000028609.1[more]
SMESG000060876.18.763e-2625.15SMESG000060876.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30019300 ID=SMED30019300|Name=Histone deacetylase,putative|organism=Schmidtea mediterranea sexual|type=transcript|length=3598bp
AAGTTTATTGTTTAAAACGATAAAAGCATCTTAATTTTAGATTATATATG
ATAAAACTTATTTTATTTTACTAATAGAATAAGATTTCGTAATTACCAGT
TACATGTCACAATCTTCACCTCGTTCCTTAAGAAGTCAGGTTCTAAGACG
GCGCAGACGGTCAAGGTCAAATTCACCGTTTGGAGATGAGGATTTACCAG
CGGCTCAATCGAATCATGGTTTATACGATAATATTGAACTCAGAATAAAT
TTTCCTAACAAAACTGCATTTGTATATGATGAACAAATGCTACTTCATTC
AAACATGTGGGATAATTTATACTTCGAACGACCAGACAGGTTGAGAGTTT
GTTATGAAGGCATATGTGAAACAAATTTATTGGAAGATTGTATTCGAATA
CAAGCTAAAGAAATAGATAACGAATTAATATATTATAGTCATTCTCAATC
CCATGTTCAGTTAATTGAAGACACACAAACTATGACAGCAATTCAGTTAA
AAGAATTGTCATCTCAACATGACTGTGTATTTTTTGACAATAATACAAAG
CTTGCTTCATTTATTTCTGCCGGTTCTACTATTGAAGTACTAAAAGCTGT
TTTGGATGACAGGGCCAAAAATGGATTTTGCTTAATTAGACCACCCGGTC
ATCATGCTATGGAATCAGAAGCCAGTGGATTTTGCATTTTTAACAATGTA
GGAATCGCAGCAAAATATGCTCAATTAAATTACTCCACGCAGAAAATTCT
AATTGTTGATTGGGATGTTCACCATGGTAATGCTACTCAATATCAATTTT
ATAACACATCAAAAGTGCTTTACATATCAATTCATCGATACGAAGACGGC
AATTTTTGGCCGAAATTGCGAGAGAGTAACTATGATTATATTGGTGCAAA
TGAAGGGAGAGGATATAATATTAATATACCTCTTAATAAAACCAATATGA
CAAATAGTGACTATTTATCAATTTTCCATAGTATTATTCTTCCTATTGCG
TACGAGTACAATCCTGAATTGGTTTTGATATCAGCTGGATTTGATTCAGC
AATCGGGTGCCCCGAAGGTTCCATGGATGTGCACCCTGCATGTTTTGCAC
ACATGACACATAAATTAATGGATTTAGCTCGTGGAAGAGTAGTTGTGCTT
CTTGAAGGCGGTTATTGCATGGAGTCTTTAAAGGATAGTGTTGTTTTGAC
ATTAGCAACACTCACAGGAAAGGCGCCTCCTAAACTCGAAAAGTTTGATG
AGCCATGTGATAGTGTGAAAGAAACAATACAAAATTGTCTGAAATTTCTT
CATTTCTTTTGGAAAAGTCTATCTGTAAATGTTGCTGATAACCACGAACC
ATATCCGGAATATTTGCGTCATTTACCAGAATCTACATGGAATTCTTCAA
AAGTTCCTAAACTTCCAATTGAAGACAATCCAAATAAATGCAAAGAAAAT
GATCAATTAAATCACAAAATCTATGAACTTAGAACCAAAAACGCATTTAA
CAACTATCCTAACAAAACGTGTTTTGTTTATGACTGTAGAATGGAGAACC
ACATGAATGAGAGATCAATTCATCCCGAATCTCCAAGAAGAACTCAAATG
ATTTTTGAATTCTTGAGAGACAACAGCTTATTAAGCCGATGTAAACAGTT
GGAGTCTCGGCTTGCATCAAAAGATGAAATAGGTTTAATTCATTCTCCAA
ATTATGTAGAGAGTTTGGGAAATATTTGCCAGGAATCCCCAACTATTTAT
CATCTATTCGAAGAGGAATTTAACTCAATATATATTAATCAACACAGTTA
CATTTCTGCTCTGCTTTCTTGTGGACTGTTATTAAATGTAATTGATGAAG
TTTGTTCTGACAGGTCGGAAAACGGTTTTGCTATTATAAGACCTCCTGGT
CACCACGCAGAAGTAAATTATCCGTTAGGATTTTGCTTTTTTAACAATGT
TGCTATTGCTGCAAATTATGCACTGACTAAATATTCAGAATCAATTAAAA
AAATTCTAATAGTGGATTGGGATGTCCATCATGGTAACGGTACTCAGCAT
CAATTTTGGACAAACAAAAATGTTTTATATATATCACTTCATCGCTATGA
TAATGGTTTATTTTTCCCCGGCAGTACAGATGGATCTCCATCTGCAGTCG
GGGGGGATGATGCTGAAGGATTTAATGTAAACATTGCTTGGAATAAGAGG
CCAGTGAGAGATTCAGAATATATTTCAGCTTTTATTAATATTGTTATGCC
TATTTCTCATGAATTCAATCCAGATTTGGTAATTGTTTCAGCTGGTTTCG
ATGCTGCTCGTGGAGATCCCCTTGGTGGATTAACTGTAACACCTGAATGT
TTCGGTAACATGACTCAAATGCTAACGTCTTTAGCCAATGGAAAAGTTAT
TTTGGCTCTAGAAGGCGGATATAATCTTAATGTCATATCTGACTGTATGT
CACATTGTGTGAGTTCTTTGTTAGGATATCCAACTAATCAAATCATTAAT
TTTCCCATAAATAAAAGTGGAATTGAAGCCATACGTAAAACGTTAGAATA
TCAAAAACCGTATTGGAAATGTCTTAAATTTTATGAACCTTTGGTGGTGA
CCTACACAGAAATTAGTCCTAATCAGACCAATCCAGCGGCACTTGACAAT
ATTGTTCAAATCGATACTAATACATTGGCAGAATCTGTCCGCCAATTAGG
AATTGTGGAAGTGACGTTCCAAACAGAGCAATCGATAGAAGAAACGTTAT
CACAACCAAGAAACGATACATTTATCACAGAACCGAATTCCTCTAATCCA
ATAATCCATTTACCGCCAATAGTGTCATCCGACAATGCTGTCGAAGTACC
TGCAACAACATCCATTAACAGCACTACTCATGCTACTCAAAATATTTCTG
CTAATTTCCTGTCAGTTGATCAGTCCAGTGGAGCTACACCTGTCAGTGCT
AATGTGTCTCGGGTCATTAATGAAGGCAACTCGGTTGGATTGGTATTGCA
AGACATCATGAATTTAAGCGGTGTCAGCAATAGCGATATTCATCACTTTC
TAGGATTGACATCAAATGATCCGCTTCCTGAACGAGTTTATGCAGTACAG
CCTCTGCTATGGTGTGAGCATTTAAATCAAGTCCAACAGTCTCCGTCTGC
TAATGAAATTGATGTAAATGCCTCATGTACTCTTTGTCCATCAACTCGTG
AAAATTGGCTATGCCTTACTTGTTACCAAGTTTTTTGTGGGCGTTTTGTT
CAAGCCCATATGATGCAACATTTCCAAAATACTAGACACGCTATAGTTCT
CAGTTTTGTGGATTTAAGCAGCTGGTGTTATGAATGCGATTCTTATGTCC
ATAATGAATGTTTAAATCATGCGAAGCGCGAGGCCCATATTGCCAAATTT
GGAGTACCTCAACCGAGTAATAGTTTATGAAGTTATATGGAATTATTTTT
TTCTACTAATGTTGTTTGTTAATTTGATATTTAAAAATAATTATTTACTT
TGACTTTTTATTTTCATTTTACAACAAAATATGTAGAGCAGGATCTAGAT
GATGGAAACTGTATCAAATTGAACATTATTCTTAAATACAAATTTAAG
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protein sequence of SMED30019300-orf-1

>SMED30019300-orf-1 ID=SMED30019300-orf-1|Name=SMED30019300-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1109bp
MSQSSPRSLRSQVLRRRRRSRSNSPFGDEDLPAAQSNHGLYDNIELRINF
PNKTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQ
AKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKL
ASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVG
IAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGN
FWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAY
EYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLL
EGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLH
FFWKSLSVNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKEND
QLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMNERSIHPESPRRTQMI
FEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYH
LFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGH
HAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQ
FWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRP
VRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECF
GNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINF
PINKSGIEAIRKTLEYQKPYWKCLKFYEPLVVTYTEISPNQTNPAALDNI
VQIDTNTLAESVRQLGIVEVTFQTEQSIEETLSQPRNDTFITEPNSSNPI
IHLPPIVSSDNAVEVPATTSINSTTHATQNISANFLSVDQSSGATPVSAN
VSRVINEGNSVGLVLQDIMNLSGVSNSDIHHFLGLTSNDPLPERVYAVQP
LLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQVFCGRFVQ
AHMMQHFQNTRHAIVLSFVDLSSWCYECDSYVHNECLNHAKREAHIAKFG
VPQPSNSL*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000020protonephridia
PLANA:0000026gut
PLANA:0000034epidermis
PLANA:0000043dorsal ventral margin of the whole animal
PLANA:0000054dorsal region of the epidermis
PLANA:0000070intestinal phagocyte
PLANA:0000099neuron
PLANA:0000101muscle cell
PLANA:0002032epidermal cell
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR037138His_deacetylse_dom_sf
IPR023696Ureohydrolase_dom_sf
IPR000286His_deacetylse
IPR001607Znf_UBP
IPR013083Znf_RING/FYVE/PHD
IPR023801His_deacetylse_dom
Vocabulary: molecular function
TermDefinition
GO:0008270zinc ion binding
GO:0016787hydrolase activity
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000286Histone deacetylase familyPRINTSPR01270HDASUPERcoord: 597..620
score: 44.39
coord: 633..648
score: 58.53
coord: 723..733
score: 49.13
IPR001607Zinc finger, UBP-typeSMARTSM00290Zf_UBP_1coord: 1025..1074
e-value: 4.0E-12
score: 56.3
IPR001607Zinc finger, UBP-typePFAMPF02148zf-UBPcoord: 1026..1087
e-value: 5.7E-17
score: 61.8
IPR001607Zinc finger, UBP-typePROSITEPS50271ZF_UBPcoord: 1024..1085
score: 17.086
IPR013083Zinc finger, RING/FYVE/PHD-typeGENE3DG3DSA:3.30.40.10coord: 999..1105
e-value: 5.3E-30
score: 105.4
IPR037138Histone deacetylase domain superfamilyGENE3DG3DSA:3.40.800.20coord: 51..409
e-value: 8.2E-131
score: 438.2
IPR037138Histone deacetylase domain superfamilyGENE3DG3DSA:3.40.800.20coord: 465..825
e-value: 2.1E-134
score: 450.1
IPR023801Histone deacetylase domainPFAMPF00850Hist_deacetylcoord: 75..369
e-value: 1.7E-78
score: 264.2
IPR023801Histone deacetylase domainPFAMPF00850Hist_deacetylcoord: 490..788
e-value: 2.2E-82
score: 277.0
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1..32
NoneNo IPR availablePANTHERPTHR45634:SF11HISTONE DEACETYLASEcoord: 50..415
coord: 463..901
NoneNo IPR availablePANTHERPTHR45634FAMILY NOT NAMEDcoord: 463..901
coord: 50..415
NoneNo IPR availableSUPERFAMILYSSF57850RING/U-boxcoord: 1002..1097
IPR023696Ureohydrolase domain superfamilySUPERFAMILYSSF52768Arginase/deacetylasecoord: 469..825
IPR023696Ureohydrolase domain superfamilySUPERFAMILYSSF52768Arginase/deacetylasecoord: 52..405