Histone deacetylase,putative
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30019300 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 16
Homology
BLAST of Histone deacetylase,putative vs. Ensembl Human
Match: HDAC6 (histone deacetylase 6 [Source:HGNC Symbol;Acc:HGNC:14064]) HSP 1 Score: 602.438 bits (1552), Expect = 0.000e+0 Identity = 315/777 (40.54%), Postives = 454/777 (58.43%), Query Frame = 2
Query: 263 TAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKENDQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMN-ERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINFPINKSG-IEAIRKTLEYQKPYWKCLKFYE 2587
T V DEQ+ +WD+ + E P+RL E + + LL+ C+ QA+ + E + HS ++ L+E TQ M +L+ L+ +D V+ N+ + +++GS + ++ AVL +NG +IRPPGHHA S G+C+FN+V +AA+YAQ + +++LIVDWDVHHG TQ+ F VLY SIHRYE G FWP L+ SN+ G +G+GY IN+P N+ M ++DY++ F ++LP+A E+ P+LVL++AGFD+ G P+G M PA FA +TH LM LA G++++ LEGGY + +L + V +L TL G P LE PC S + ++ L+ L FW+ L + E + P LPI L + + RT VYD M NH N S HPE P+R I L + L RC L R A++ E+ HS YV L + H F+SIYI ++ A L+ G +++ V S NG A++RPPGHHAE + GFCFFN+VA+AA +A T ++ +ILIVDWDVHHGNGTQH F + +VLY+SLHRYD+G FFP +G+ S +G GF VN+AWN + D++Y++A+ +V+PI++EFNP+LV+VSAGFDAARGDPLGG V+PE + ++T +L LA+G++IL LEGGYNL IS+ M+ C SLLG P + SG + +I +T++ + YW+ L+ +
Sbjct: 86 TGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHPNSYSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQKHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATPAGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSAQASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPPVLPI------------LTWPVLQSRTG-----------LVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHAL-RILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMK 838 HSP 2 Score: 270.011 bits (689), Expect = 8.515e-74 Identity = 138/365 (37.81%), Postives = 211/365 (57.81%), Query Frame = 2
Query: 257 NKTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQ-LNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHE 1348
++T VYD+ M+ H N+WD+ + E P R+ + E L C+ + + + HS +V + T+ M +L SS D ++ +T + ++ G+ +++AVL NG ++RPPGHHA + A GFC FN+V +AA++AQ ++ +ILIVDWDVHHGN TQ+ F + VLY+S+HRY+ G F+P E IG G G+ +N+ N M ++DYL+ +H ++LPIAYE+NPELVL+SAGFD+A G P G V P +AH+TH LM LA GR++++LEGGY + S+ +S+ +L G PP L P +I ++ +W+SL V ++ E
Sbjct: 479 SRTGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVEDRE 843 HSP 3 Score: 128.257 bits (321), Expect = 4.255e-29 Identity = 88/283 (31.10%), Postives = 132/283 (46.64%), Query Frame = 2
Query: 2615 SPNQTNP------AALDNIVQIDT---NTLAESVRQLGIVEVTFQTEQSIEETLSQPRNDTFITEPNSSNPIIHLPPIVSSDNAVEVPATTSINSTTHATQNISANFLSVDQSS---GATPVSANVSRVINEGNSVGLVLQDIMNLSGVSNSDIHHFLGLTSNDPLPERV--YAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQVFCGRFVQAHMMQHFQNTRHAIVLSFVDLSSWCYECDSYVHNECLNHAKREAHIAKFG--VPQP 3415
+P+QT A LD D TL ++ + + T S + T E +I P S+D+ + P T+ + TT IS + L + G+ A+ S+ E N +G D+ + + + L ++ YAV PL WC HL V P+A +DV C C + +ENW+CL+CYQV+CGR++ HM+QH N+ H +VLS++DLS+WCY C +YVH++ L K AH KFG +P P
Sbjct: 947 TPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDH--QTPPTSPVQGTT---PQISPSTLIGSLRTLELGSESQGASESQAPGEENLLG---------EAAGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAG-LDVTQPCGDCGTIQENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYVHHQALLDVKNIAHQNKFGEDMPHP 1214
BLAST of Histone deacetylase,putative vs. Ensembl Human
Match: HDAC6 (histone deacetylase 6 [Source:HGNC Symbol;Acc:HGNC:14064]) HSP 1 Score: 602.438 bits (1552), Expect = 0.000e+0 Identity = 315/777 (40.54%), Postives = 454/777 (58.43%), Query Frame = 2
Query: 263 TAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKENDQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMN-ERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINFPINKSG-IEAIRKTLEYQKPYWKCLKFYE 2587
T V DEQ+ +WD+ + E P+RL E + + LL+ C+ QA+ + E + HS ++ L+E TQ M +L+ L+ +D V+ N+ + +++GS + ++ AVL +NG +IRPPGHHA S G+C+FN+V +AA+YAQ + +++LIVDWDVHHG TQ+ F VLY SIHRYE G FWP L+ SN+ G +G+GY IN+P N+ M ++DY++ F ++LP+A E+ P+LVL++AGFD+ G P+G M PA FA +TH LM LA G++++ LEGGY + +L + V +L TL G P LE PC S + ++ L+ L FW+ L + E + P LPI L + + RT VYD M NH N S HPE P+R I L + L RC L R A++ E+ HS YV L + H F+SIYI ++ A L+ G +++ V S NG A++RPPGHHAE + GFCFFN+VA+AA +A T ++ +ILIVDWDVHHGNGTQH F + +VLY+SLHRYD+G FFP +G+ S +G GF VN+AWN + D++Y++A+ +V+PI++EFNP+LV+VSAGFDAARGDPLGG V+PE + ++T +L LA+G++IL LEGGYNL IS+ M+ C SLLG P + SG + +I +T++ + YW+ L+ +
Sbjct: 86 TGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHPNSYSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQKHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATPAGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSAQASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPPVLPI------------LTWPVLQSRTG-----------LVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHAL-RILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMK 838 HSP 2 Score: 270.011 bits (689), Expect = 8.515e-74 Identity = 138/365 (37.81%), Postives = 211/365 (57.81%), Query Frame = 2
Query: 257 NKTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQ-LNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHE 1348
++T VYD+ M+ H N+WD+ + E P R+ + E L C+ + + + HS +V + T+ M +L SS D ++ +T + ++ G+ +++AVL NG ++RPPGHHA + A GFC FN+V +AA++AQ ++ +ILIVDWDVHHGN TQ+ F + VLY+S+HRY+ G F+P E IG G G+ +N+ N M ++DYL+ +H ++LPIAYE+NPELVL+SAGFD+A G P G V P +AH+TH LM LA GR++++LEGGY + S+ +S+ +L G PP L P +I ++ +W+SL V ++ E
Sbjct: 479 SRTGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVEDRE 843 HSP 3 Score: 128.257 bits (321), Expect = 4.255e-29 Identity = 88/283 (31.10%), Postives = 132/283 (46.64%), Query Frame = 2
Query: 2615 SPNQTNP------AALDNIVQIDT---NTLAESVRQLGIVEVTFQTEQSIEETLSQPRNDTFITEPNSSNPIIHLPPIVSSDNAVEVPATTSINSTTHATQNISANFLSVDQSS---GATPVSANVSRVINEGNSVGLVLQDIMNLSGVSNSDIHHFLGLTSNDPLPERV--YAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQVFCGRFVQAHMMQHFQNTRHAIVLSFVDLSSWCYECDSYVHNECLNHAKREAHIAKFG--VPQP 3415
+P+QT A LD D TL ++ + + T S + T E +I P S+D+ + P T+ + TT IS + L + G+ A+ S+ E N +G D+ + + + L ++ YAV PL WC HL V P+A +DV C C + +ENW+CL+CYQV+CGR++ HM+QH N+ H +VLS++DLS+WCY C +YVH++ L K AH KFG +P P
Sbjct: 947 TPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDH--QTPPTSPVQGTT---PQISPSTLIGSLRTLELGSESQGASESQAPGEENLLG---------EAAGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAG-LDVTQPCGDCGTIQENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYVHHQALLDVKNIAHQNKFGEDMPHP 1214
BLAST of Histone deacetylase,putative vs. Ensembl Human
Match: HDAC6 (histone deacetylase 6 [Source:HGNC Symbol;Acc:HGNC:14064]) HSP 1 Score: 602.438 bits (1552), Expect = 0.000e+0 Identity = 315/777 (40.54%), Postives = 454/777 (58.43%), Query Frame = 2
Query: 263 TAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKENDQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMN-ERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINFPINKSG-IEAIRKTLEYQKPYWKCLKFYE 2587
T V DEQ+ +WD+ + E P+RL E + + LL+ C+ QA+ + E + HS ++ L+E TQ M +L+ L+ +D V+ N+ + +++GS + ++ AVL +NG +IRPPGHHA S G+C+FN+V +AA+YAQ + +++LIVDWDVHHG TQ+ F VLY SIHRYE G FWP L+ SN+ G +G+GY IN+P N+ M ++DY++ F ++LP+A E+ P+LVL++AGFD+ G P+G M PA FA +TH LM LA G++++ LEGGY + +L + V +L TL G P LE PC S + ++ L+ L FW+ L + E + P LPI L + + RT VYD M NH N S HPE P+R I L + L RC L R A++ E+ HS YV L + H F+SIYI ++ A L+ G +++ V S NG A++RPPGHHAE + GFCFFN+VA+AA +A T ++ +ILIVDWDVHHGNGTQH F + +VLY+SLHRYD+G FFP +G+ S +G GF VN+AWN + D++Y++A+ +V+PI++EFNP+LV+VSAGFDAARGDPLGG V+PE + ++T +L LA+G++IL LEGGYNL IS+ M+ C SLLG P + SG + +I +T++ + YW+ L+ +
Sbjct: 86 TGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHPNSYSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQKHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATPAGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSAQASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPPVLPI------------LTWPVLQSRTG-----------LVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHAL-RILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMK 838 HSP 2 Score: 270.011 bits (689), Expect = 8.515e-74 Identity = 138/365 (37.81%), Postives = 211/365 (57.81%), Query Frame = 2
Query: 257 NKTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQ-LNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHE 1348
++T VYD+ M+ H N+WD+ + E P R+ + E L C+ + + + HS +V + T+ M +L SS D ++ +T + ++ G+ +++AVL NG ++RPPGHHA + A GFC FN+V +AA++AQ ++ +ILIVDWDVHHGN TQ+ F + VLY+S+HRY+ G F+P E IG G G+ +N+ N M ++DYL+ +H ++LPIAYE+NPELVL+SAGFD+A G P G V P +AH+TH LM LA GR++++LEGGY + S+ +S+ +L G PP L P +I ++ +W+SL V ++ E
Sbjct: 479 SRTGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVEDRE 843 HSP 3 Score: 128.257 bits (321), Expect = 4.255e-29 Identity = 88/283 (31.10%), Postives = 132/283 (46.64%), Query Frame = 2
Query: 2615 SPNQTNP------AALDNIVQIDT---NTLAESVRQLGIVEVTFQTEQSIEETLSQPRNDTFITEPNSSNPIIHLPPIVSSDNAVEVPATTSINSTTHATQNISANFLSVDQSS---GATPVSANVSRVINEGNSVGLVLQDIMNLSGVSNSDIHHFLGLTSNDPLPERV--YAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQVFCGRFVQAHMMQHFQNTRHAIVLSFVDLSSWCYECDSYVHNECLNHAKREAHIAKFG--VPQP 3415
+P+QT A LD D TL ++ + + T S + T E +I P S+D+ + P T+ + TT IS + L + G+ A+ S+ E N +G D+ + + + L ++ YAV PL WC HL V P+A +DV C C + +ENW+CL+CYQV+CGR++ HM+QH N+ H +VLS++DLS+WCY C +YVH++ L K AH KFG +P P
Sbjct: 947 TPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDH--QTPPTSPVQGTT---PQISPSTLIGSLRTLELGSESQGASESQAPGEENLLG---------EAAGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAG-LDVTQPCGDCGTIQENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYVHHQALLDVKNIAHQNKFGEDMPHP 1214
BLAST of Histone deacetylase,putative vs. Ensembl Human
Match: HDAC6 (histone deacetylase 6 [Source:HGNC Symbol;Acc:HGNC:14064]) HSP 1 Score: 602.438 bits (1552), Expect = 0.000e+0 Identity = 315/777 (40.54%), Postives = 454/777 (58.43%), Query Frame = 2
Query: 263 TAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKENDQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMN-ERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINFPINKSG-IEAIRKTLEYQKPYWKCLKFYE 2587
T V DEQ+ +WD+ + E P+RL E + + LL+ C+ QA+ + E + HS ++ L+E TQ M +L+ L+ +D V+ N+ + +++GS + ++ AVL +NG +IRPPGHHA S G+C+FN+V +AA+YAQ + +++LIVDWDVHHG TQ+ F VLY SIHRYE G FWP L+ SN+ G +G+GY IN+P N+ M ++DY++ F ++LP+A E+ P+LVL++AGFD+ G P+G M PA FA +TH LM LA G++++ LEGGY + +L + V +L TL G P LE PC S + ++ L+ L FW+ L + E + P LPI L + + RT VYD M NH N S HPE P+R I L + L RC L R A++ E+ HS YV L + H F+SIYI ++ A L+ G +++ V S NG A++RPPGHHAE + GFCFFN+VA+AA +A T ++ +ILIVDWDVHHGNGTQH F + +VLY+SLHRYD+G FFP +G+ S +G GF VN+AWN + D++Y++A+ +V+PI++EFNP+LV+VSAGFDAARGDPLGG V+PE + ++T +L LA+G++IL LEGGYNL IS+ M+ C SLLG P + SG + +I +T++ + YW+ L+ +
Sbjct: 86 TGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHPNSYSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQKHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATPAGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSAQASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPPVLPI------------LTWPVLQSRTG-----------LVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHAL-RILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMK 838 HSP 2 Score: 270.011 bits (689), Expect = 8.515e-74 Identity = 138/365 (37.81%), Postives = 211/365 (57.81%), Query Frame = 2
Query: 257 NKTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQ-LNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHE 1348
++T VYD+ M+ H N+WD+ + E P R+ + E L C+ + + + HS +V + T+ M +L SS D ++ +T + ++ G+ +++AVL NG ++RPPGHHA + A GFC FN+V +AA++AQ ++ +ILIVDWDVHHGN TQ+ F + VLY+S+HRY+ G F+P E IG G G+ +N+ N M ++DYL+ +H ++LPIAYE+NPELVL+SAGFD+A G P G V P +AH+TH LM LA GR++++LEGGY + S+ +S+ +L G PP L P +I ++ +W+SL V ++ E
Sbjct: 479 SRTGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVEDRE 843 HSP 3 Score: 128.257 bits (321), Expect = 4.255e-29 Identity = 88/283 (31.10%), Postives = 132/283 (46.64%), Query Frame = 2
Query: 2615 SPNQTNP------AALDNIVQIDT---NTLAESVRQLGIVEVTFQTEQSIEETLSQPRNDTFITEPNSSNPIIHLPPIVSSDNAVEVPATTSINSTTHATQNISANFLSVDQSS---GATPVSANVSRVINEGNSVGLVLQDIMNLSGVSNSDIHHFLGLTSNDPLPERV--YAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQVFCGRFVQAHMMQHFQNTRHAIVLSFVDLSSWCYECDSYVHNECLNHAKREAHIAKFG--VPQP 3415
+P+QT A LD D TL ++ + + T S + T E +I P S+D+ + P T+ + TT IS + L + G+ A+ S+ E N +G D+ + + + L ++ YAV PL WC HL V P+A +DV C C + +ENW+CL+CYQV+CGR++ HM+QH N+ H +VLS++DLS+WCY C +YVH++ L K AH KFG +P P
Sbjct: 947 TPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDH--QTPPTSPVQGTT---PQISPSTLIGSLRTLELGSESQGASESQAPGEENLLG---------EAAGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAG-LDVTQPCGDCGTIQENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYVHHQALLDVKNIAHQNKFGEDMPHP 1214
BLAST of Histone deacetylase,putative vs. Ensembl Human
Match: HDAC6 (histone deacetylase 6 [Source:HGNC Symbol;Acc:HGNC:14064]) HSP 1 Score: 601.668 bits (1550), Expect = 0.000e+0 Identity = 315/777 (40.54%), Postives = 454/777 (58.43%), Query Frame = 2
Query: 263 TAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKENDQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMN-ERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINFPINKSG-IEAIRKTLEYQKPYWKCLKFYE 2587
T V DEQ+ +WD+ + E P+RL E + + LL+ C+ QA+ + E + HS ++ L+E TQ M +L+ L+ +D V+ N+ + +++GS + ++ AVL +NG +IRPPGHHA S G+C+FN+V +AA+YAQ + +++LIVDWDVHHG TQ+ F VLY SIHRYE G FWP L+ SN+ G +G+GY IN+P N+ M ++DY++ F ++LP+A E+ P+LVL++AGFD+ G P+G M PA FA +TH LM LA G++++ LEGGY + +L + V +L TL G P LE PC S + ++ L+ L FW+ L + E + P LPI L + + RT VYD M NH N S HPE P+R I L + L RC L R A++ E+ HS YV L + H F+SIYI ++ A L+ G +++ V S NG A++RPPGHHAE + GFCFFN+VA+AA +A T ++ +ILIVDWDVHHGNGTQH F + +VLY+SLHRYD+G FFP +G+ S +G GF VN+AWN + D++Y++A+ +V+PI++EFNP+LV+VSAGFDAARGDPLGG V+PE + ++T +L LA+G++IL LEGGYNL IS+ M+ C SLLG P + SG + +I +T++ + YW+ L+ +
Sbjct: 31 TGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHPNSYSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQKHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATPAGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSAQASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPPVLPI------------LTWPVLQSRTG-----------LVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHAL-RILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMK 783 HSP 2 Score: 269.626 bits (688), Expect = 8.732e-74 Identity = 138/365 (37.81%), Postives = 211/365 (57.81%), Query Frame = 2
Query: 257 NKTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQ-LNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHE 1348
++T VYD+ M+ H N+WD+ + E P R+ + E L C+ + + + HS +V + T+ M +L SS D ++ +T + ++ G+ +++AVL NG ++RPPGHHA + A GFC FN+V +AA++AQ ++ +ILIVDWDVHHGN TQ+ F + VLY+S+HRY+ G F+P E IG G G+ +N+ N M ++DYL+ +H ++LPIAYE+NPELVL+SAGFD+A G P G V P +AH+TH LM LA GR++++LEGGY + S+ +S+ +L G PP L P +I ++ +W+SL V ++ E
Sbjct: 424 SRTGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVEDRE 788 HSP 3 Score: 128.642 bits (322), Expect = 3.133e-29 Identity = 88/283 (31.10%), Postives = 132/283 (46.64%), Query Frame = 2
Query: 2615 SPNQTNP------AALDNIVQIDT---NTLAESVRQLGIVEVTFQTEQSIEETLSQPRNDTFITEPNSSNPIIHLPPIVSSDNAVEVPATTSINSTTHATQNISANFLSVDQSS---GATPVSANVSRVINEGNSVGLVLQDIMNLSGVSNSDIHHFLGLTSNDPLPERV--YAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQVFCGRFVQAHMMQHFQNTRHAIVLSFVDLSSWCYECDSYVHNECLNHAKREAHIAKFG--VPQP 3415
+P+QT A LD D TL ++ + + T S + T E +I P S+D+ + P T+ + TT IS + L + G+ A+ S+ E N +G D+ + + + L ++ YAV PL WC HL V P+A +DV C C + +ENW+CL+CYQV+CGR++ HM+QH N+ H +VLS++DLS+WCY C +YVH++ L K AH KFG +P P
Sbjct: 892 TPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDH--QTPPTSPVQGTT---PQISPSTLIGSLRTLELGSESQGASESQAPGEENLLG---------EAAGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAG-LDVTQPCGDCGTIQENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYVHHQALLDVKNIAHQNKFGEDMPHP 1159
BLAST of Histone deacetylase,putative vs. Ensembl Celegans
Match: hda-6 (Histone deacetylase 6 [Source:UniProtKB/Swiss-Prot;Acc:Q20296]) HSP 1 Score: 486.493 bits (1251), Expect = 4.323e-155 Identity = 280/773 (36.22%), Postives = 423/773 (54.72%), Query Frame = 2
Query: 326 ERPDRLRVCYEGICETNLLEDC-IRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKENDQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMN-ERSIHPESPRRTQMIFEFLRDNSLLSRCKQLE-SRLASKDEIGLIHSPNYVESLGNI-CQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRS--ENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSL--------LGYPTNQIINFP--INKSGIEAIRKTLEYQKPYWKCLKFYEPLV 2596
E DR+ E + +T +LE C + EID+ + +H +S V+ + +++ T + ++D VF N+ + ++ ++ + A NGF ++RPPGHHA GFC+FNNV AA+ A + ++ILIVD DVHHG+ TQ FY+ +VLY SIHR+E G FWP L ES++D+IG+ +G GYN N+ LN+T T+SDYLSI ++LP+A +++P V+ISAGFD+ +G P G M + P ++H+ + L LA+GR++V+LEGGY + +V + L G AP +E + P +S ++ + + L W ++ P LR N+ + E Q E + +T ++ + H + E HPE P RT+ I + LR++ +L +C R+A+ +EI L+H+ +E L + + E+EFNSIY+ + + A + G +L +DE+ + N I+RPPGHHA + GFC FNNVA+AA YA ++ K++LI+DWDVHHGNGTQ F+ + NV+Y+S+HR+D G F+P S VG EG +VN+ ++ + D+EY AF ++MPI+++FNPDLV++SAGFDAA DPLG VTPE F MT L+SLA G++I LEGGYNL IS+ L L Q P I S I+ IR+ Q+ YW LK ++ ++
Sbjct: 36 ESSDRILKIKEALTKTKILEKCTVLTNFLEIDDADLEVTHDKSMVKDLMESEKKTQEDINSQCEKYDSVFMTENSMKVAKDGVACVRDLTNRIMANEASNGFAVVRPPGHHADSVSPCGFCLFNNVAQAAEEAFFS-GAERILIVDLDVHHGHGTQRIFYDDKRVLYFSIHRHEHGLFWPHLPESDFDHIGSGKGLGYNANLALNETGCTDSDYLSIIFHVLLPLATQFDPHFVIISAGFDALLGDPLGGMCLTPDGYSHILYHLKSLAQGRMLVVLEGGYNHQISAVAVQRCVRVLLGYAPFSIELNEAPKESTVDSCVSLVSVLRHHWNCF------DYFPSRTSLRLAQWPIVNTKVIYNYDPTTRRADTGEIIQDELASTEFTASDVIPTENMETLIYFNEGDDAHFDLEEDNHPEKPARTRRILKTLRESGVLEKCVDRNCERIATNEEIRLVHTKKMLEHLRTTETMKDEELMEEAEKEFNSIYLTRDTLKVARKAVGAVLQSVDEIFEKDAGQRNALVIVRPPGHHASASKSSGFCIFNNVAVAAKYAQRRHKA--KRVLILDWDVHHGNGTQEIFYEDSNVMYMSIHRHDKGNFYPIGEPKDYSDVGEGAGEGMSVNVPFSGVQMGDNEYQMAFQRVIMPIAYQFNPDLVLISAGFDAAVDDPLGEYKVTPETFALMTYQLSSLAGGRIITVLEGGYNLTSISNSAQAVCEVLQNRSMLRRLREEKEQFATKPQKIESSCIKTIREVCAVQQKYWSILKGFQIII 799 HSP 2 Score: 242.662 bits (618), Expect = 1.598e-66 Identity = 119/326 (36.50%), Postives = 197/326 (60.43%), Query Frame = 2
Query: 260 KTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEI-DNELIYYSHSQSHVQLIEDTQTMT-AIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRA--KNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKA 1225
+T ++E H ++ ++ + E+P R R + + E+ +LE C+ + I NE I H++ ++ + T+TM ++E + + ++ +T + + G+ ++ + + + A +N ++RPPGHHA S++SGFCIFNNV +AAKYAQ + +++LI+DWDVHHGN TQ FY S V+Y+SIHR++ GNF+P +Y +G G G ++N+P + M +++Y F +I+PIAY++NP+LVLISAGFD+A+ P G V P FA MT++L LA GR++ +LEGGY + S+ +S L ++
Sbjct: 426 ETLIYFNEGDDAHFDLEEDNHPEKPARTRRILKTLRESGVLEKCVDRNCERIATNEEIRLVHTKKMLEHLRTTETMKDEELMEEAEKEFNSIYLTRDTLKVARKAVGAVLQSVDEIFEKDAGQRNALVIVRPPGHHASASKSSGFCIFNNVAVAAKYAQRRHKAKRVLILDWDVHHGNGTQEIFYEDSNVMYMSIHRHDKGNFYPIGEPKDYSDVGEGAGEGMSVNVPFSGVQMGDNEYQMAFQRVIMPIAYQFNPDLVLISAGFDAAVDDPLGEYKVTPETFALMTYQLSSLAGGRIITVLEGGYNLTSISNSAQAVCEVLQNRS 751 HSP 3 Score: 235.343 bits (599), Expect = 4.538e-64 Identity = 120/340 (35.29%), Postives = 201/340 (59.12%), Query Frame = 2
Query: 1571 HPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKD-EIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGY-PTNQIINFPINKSGIEAIRKTLEYQKPYWKCLKFY 2584
HPES R I E L +L +C L + L D ++ + H + V+ L +++ + E+++S+++ ++S A + ++ + + ++ + NGFA++RPPGHHA+ P GFC FNNVA AA A +E +ILIVD DVHHG+GTQ F+ +K VLY S+HR+++GLF+P + +G G+N N+A N+ DS+Y+S ++++P++ +F+P VI+SAGFDA GDPLGG+ +TP+ + ++ L SLA G++++ LEGGYN + + + CV LLGY P + +N +S +++ + + +W C ++
Sbjct: 34 HPESSDRILKIKEALTKTKILEKCTVLTNFLEIDDADLEVTHDKSMVKDLMESEKKTQEDINSQCEKYDSVFMTENSMKVAKDGVACVRDLTNRIMANEASNGFAVVRPPGHHADSVSPCGFCLFNNVAQAAEEAFFSGAE---RILIVDLDVHHGHGTQRIFYDDKRVLYFSIHRHEHGLFWPHLPESDFDHIGSGKGLGYNANLALNETGCTDSDYLSIIFHVLLPLATQFDPHFVIISAGFDALLGDPLGGMCLTPDGYSHILYHLKSLAQGRMLVVLEGGYNHQISAVAVQRCVRVLLGYAPFSIELNEAPKESTVDSCVSLVSVLRHHWNCFDYF 370
BLAST of Histone deacetylase,putative vs. Ensembl Celegans
Match: hda-6 (Histone deacetylase 6 [Source:UniProtKB/Swiss-Prot;Acc:Q20296]) HSP 1 Score: 486.493 bits (1251), Expect = 4.323e-155 Identity = 280/773 (36.22%), Postives = 423/773 (54.72%), Query Frame = 2
Query: 326 ERPDRLRVCYEGICETNLLEDC-IRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKENDQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMN-ERSIHPESPRRTQMIFEFLRDNSLLSRCKQLE-SRLASKDEIGLIHSPNYVESLGNI-CQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRS--ENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSL--------LGYPTNQIINFP--INKSGIEAIRKTLEYQKPYWKCLKFYEPLV 2596
E DR+ E + +T +LE C + EID+ + +H +S V+ + +++ T + ++D VF N+ + ++ ++ + A NGF ++RPPGHHA GFC+FNNV AA+ A + ++ILIVD DVHHG+ TQ FY+ +VLY SIHR+E G FWP L ES++D+IG+ +G GYN N+ LN+T T+SDYLSI ++LP+A +++P V+ISAGFD+ +G P G M + P ++H+ + L LA+GR++V+LEGGY + +V + L G AP +E + P +S ++ + + L W ++ P LR N+ + E Q E + +T ++ + H + E HPE P RT+ I + LR++ +L +C R+A+ +EI L+H+ +E L + + E+EFNSIY+ + + A + G +L +DE+ + N I+RPPGHHA + GFC FNNVA+AA YA ++ K++LI+DWDVHHGNGTQ F+ + NV+Y+S+HR+D G F+P S VG EG +VN+ ++ + D+EY AF ++MPI+++FNPDLV++SAGFDAA DPLG VTPE F MT L+SLA G++I LEGGYNL IS+ L L Q P I S I+ IR+ Q+ YW LK ++ ++
Sbjct: 36 ESSDRILKIKEALTKTKILEKCTVLTNFLEIDDADLEVTHDKSMVKDLMESEKKTQEDINSQCEKYDSVFMTENSMKVAKDGVACVRDLTNRIMANEASNGFAVVRPPGHHADSVSPCGFCLFNNVAQAAEEAFFS-GAERILIVDLDVHHGHGTQRIFYDDKRVLYFSIHRHEHGLFWPHLPESDFDHIGSGKGLGYNANLALNETGCTDSDYLSIIFHVLLPLATQFDPHFVIISAGFDALLGDPLGGMCLTPDGYSHILYHLKSLAQGRMLVVLEGGYNHQISAVAVQRCVRVLLGYAPFSIELNEAPKESTVDSCVSLVSVLRHHWNCF------DYFPSRTSLRLAQWPIVNTKVIYNYDPTTRRADTGEIIQDELASTEFTASDVIPTENMETLIYFNEGDDAHFDLEEDNHPEKPARTRRILKTLRESGVLEKCVDRNCERIATNEEIRLVHTKKMLEHLRTTETMKDEELMEEAEKEFNSIYLTRDTLKVARKAVGAVLQSVDEIFEKDAGQRNALVIVRPPGHHASASKSSGFCIFNNVAVAAKYAQRRHKA--KRVLILDWDVHHGNGTQEIFYEDSNVMYMSIHRHDKGNFYPIGEPKDYSDVGEGAGEGMSVNVPFSGVQMGDNEYQMAFQRVIMPIAYQFNPDLVLISAGFDAAVDDPLGEYKVTPETFALMTYQLSSLAGGRIITVLEGGYNLTSISNSAQAVCEVLQNRSMLRRLREEKEQFATKPQKIESSCIKTIREVCAVQQKYWSILKGFQIII 799 HSP 2 Score: 242.662 bits (618), Expect = 1.598e-66 Identity = 119/326 (36.50%), Postives = 197/326 (60.43%), Query Frame = 2
Query: 260 KTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEI-DNELIYYSHSQSHVQLIEDTQTMT-AIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRA--KNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKA 1225
+T ++E H ++ ++ + E+P R R + + E+ +LE C+ + I NE I H++ ++ + T+TM ++E + + ++ +T + + G+ ++ + + + A +N ++RPPGHHA S++SGFCIFNNV +AAKYAQ + +++LI+DWDVHHGN TQ FY S V+Y+SIHR++ GNF+P +Y +G G G ++N+P + M +++Y F +I+PIAY++NP+LVLISAGFD+A+ P G V P FA MT++L LA GR++ +LEGGY + S+ +S L ++
Sbjct: 426 ETLIYFNEGDDAHFDLEEDNHPEKPARTRRILKTLRESGVLEKCVDRNCERIATNEEIRLVHTKKMLEHLRTTETMKDEELMEEAEKEFNSIYLTRDTLKVARKAVGAVLQSVDEIFEKDAGQRNALVIVRPPGHHASASKSSGFCIFNNVAVAAKYAQRRHKAKRVLILDWDVHHGNGTQEIFYEDSNVMYMSIHRHDKGNFYPIGEPKDYSDVGEGAGEGMSVNVPFSGVQMGDNEYQMAFQRVIMPIAYQFNPDLVLISAGFDAAVDDPLGEYKVTPETFALMTYQLSSLAGGRIITVLEGGYNLTSISNSAQAVCEVLQNRS 751 HSP 3 Score: 235.343 bits (599), Expect = 4.538e-64 Identity = 120/340 (35.29%), Postives = 201/340 (59.12%), Query Frame = 2
Query: 1571 HPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKD-EIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGY-PTNQIINFPINKSGIEAIRKTLEYQKPYWKCLKFY 2584
HPES R I E L +L +C L + L D ++ + H + V+ L +++ + E+++S+++ ++S A + ++ + + ++ + NGFA++RPPGHHA+ P GFC FNNVA AA A +E +ILIVD DVHHG+GTQ F+ +K VLY S+HR+++GLF+P + +G G+N N+A N+ DS+Y+S ++++P++ +F+P VI+SAGFDA GDPLGG+ +TP+ + ++ L SLA G++++ LEGGYN + + + CV LLGY P + +N +S +++ + + +W C ++
Sbjct: 34 HPESSDRILKIKEALTKTKILEKCTVLTNFLEIDDADLEVTHDKSMVKDLMESEKKTQEDINSQCEKYDSVFMTENSMKVAKDGVACVRDLTNRIMANEASNGFAVVRPPGHHADSVSPCGFCLFNNVAQAAEEAFFSGAE---RILIVDLDVHHGHGTQRIFYDDKRVLYFSIHRHEHGLFWPHLPESDFDHIGSGKGLGYNANLALNETGCTDSDYLSIIFHVLLPLATQFDPHFVIISAGFDALLGDPLGGMCLTPDGYSHILYHLKSLAQGRMLVVLEGGYNHQISAVAVQRCVRVLLGYAPFSIELNEAPKESTVDSCVSLVSVLRHHWNCFDYF 370
BLAST of Histone deacetylase,putative vs. Ensembl Celegans
Match: hda-6 (Histone deacetylase 6 [Source:UniProtKB/Swiss-Prot;Acc:Q20296]) HSP 1 Score: 484.182 bits (1245), Expect = 3.100e-153 Identity = 282/780 (36.15%), Postives = 424/780 (54.36%), Query Frame = 2
Query: 296 HSNMWDNLYFERPDRLRVCYEGICETNLLEDC-IRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKENDQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMN-ERSIHPESPRRTQMIFEFLRDNSLLSRCKQLE-SRLASKDEIGLIHSPNYVESLGNI-CQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRS--ENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSL--------LGYPTNQIINFP--INKSGIEAIRKTLEYQKPYWKCLKFYE 2587
H N + E DR+ E + +T +LE C + EID+ + +H +S V+ + +++ T + ++D VF N+ + ++ ++ + A NGF ++RPPGHHA GFC+FNNV AA+ A + ++ILIVD DVHHG+ TQ FY+ +VLY SIHR+E G FWP L ES++D+IG+ +G GYN N+ LN+T T+SDYLSI ++LP+A +++P V+ISAGFD+ +G P G M + P ++H+ + L LA+GR++V+LEGGY + +V + L G AP +E + P +S ++ + + L W ++ P LR N+ + E Q E + +T ++ + H + E HPE P RT+ I + LR++ +L +C R+A+ +EI L+H+ +E L + + E+EFNSIY+ + + A + G +L +DE+ + N I+RPPGHHA + GFC FNNVA+AA YA ++ K++LI+DWDVHHGNGTQ F+ + NV+Y+S+HR+D G F+P S VG EG +VN+ ++ + D+EY AF ++MPI+++FNPDLV++SAGFDAA DPLG VTPE F MT L+SLA G++I LEGGYNL IS+ L L Q P I S I+ IR+ Q+ YW LK ++
Sbjct: 26 HENTVCPTHPESSDRILKIKEALTKTKILEKCTVLTNFLEIDDADLEVTHDKSMVKDLMESEKKTQEDINSQCEKYDSVFMTENSMKVAKDGVACVRDLTNRIMANEASNGFAVVRPPGHHADSVSPCGFCLFNNVAQAAEEAFFS-GAERILIVDLDVHHGHGTQRIFYDDKRVLYFSIHRHEHGLFWPHLPESDFDHIGSGKGLGYNANLALNETGCTDSDYLSIIFHVLLPLATQFDPHFVIISAGFDALLGDPLGGMCLTPDGYSHILYHLKSLAQGRMLVVLEGGYNHQISAVAVQRCVRVLLGYAPFSIELNEAPKESTVDSCVSLVSVLRHHWNCF------DYFPSRTSLRLAQWPIVNTKVIYNYDPTTRRADTGEIIQDELASTEFTASDVIPTENMETLIYFNEGDDAHFDLEEDNHPEKPARTRRILKTLRESGVLEKCVDRNCERIATNEEIRLVHTKKMLEHLRTTETMKDEELMEEAEKEFNSIYLTRDTLKVARKAVGAVLQSVDEIFEKDAGQRNALVIVRPPGHHASASKSSGFCIFNNVAVAAKYAQRRHKA--KRVLILDWDVHHGNGTQEIFYEDSNVMYMSIHRHDKGNFYPIGEPKDYSDVGEGAGEGMSVNVPFSGVQMGDNEYQMAFQRVIMPIAYQFNPDLVLISAGFDAAVDDPLGEYKVTPETFALMTYQLSSLAGGRIITVLEGGYNLTSISNSAQAVCEVLQNRSMLRRLREEKEQFATKPQKIESSCIKTIREVCAVQQKYWSILKGFQ 796 HSP 2 Score: 242.662 bits (618), Expect = 4.885e-66 Identity = 119/326 (36.50%), Postives = 197/326 (60.43%), Query Frame = 2
Query: 260 KTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEI-DNELIYYSHSQSHVQLIEDTQTMT-AIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRA--KNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKA 1225
+T ++E H ++ ++ + E+P R R + + E+ +LE C+ + I NE I H++ ++ + T+TM ++E + + ++ +T + + G+ ++ + + + A +N ++RPPGHHA S++SGFCIFNNV +AAKYAQ + +++LI+DWDVHHGN TQ FY S V+Y+SIHR++ GNF+P +Y +G G G ++N+P + M +++Y F +I+PIAY++NP+LVLISAGFD+A+ P G V P FA MT++L LA GR++ +LEGGY + S+ +S L ++
Sbjct: 426 ETLIYFNEGDDAHFDLEEDNHPEKPARTRRILKTLRESGVLEKCVDRNCERIATNEEIRLVHTKKMLEHLRTTETMKDEELMEEAEKEFNSIYLTRDTLKVARKAVGAVLQSVDEIFEKDAGQRNALVIVRPPGHHASASKSSGFCIFNNVAVAAKYAQRRHKAKRVLILDWDVHHGNGTQEIFYEDSNVMYMSIHRHDKGNFYPIGEPKDYSDVGEGAGEGMSVNVPFSGVQMGDNEYQMAFQRVIMPIAYQFNPDLVLISAGFDAAVDDPLGEYKVTPETFALMTYQLSSLAGGRIITVLEGGYNLTSISNSAQAVCEVLQNRS 751 HSP 3 Score: 112.464 bits (280), Expect = 7.471e-25 Identity = 54/111 (48.65%), Postives = 66/111 (59.46%), Query Frame = 2
Query: 3086 VYAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQVFCGRFVQAHMMQHFQNTRHAIVLSFVDLSSWCYECDSYVHNECLNHAKREAHIAKFGVPQPS 3418
+AV PL C HL +V+ P A +I+ +C+ C E W CLTCY+ CGRFV H M H ++ H + LS DLS WCY CDSYVHN L AK AH +KFG PS
Sbjct: 846 AHAVVPLATCPHLKEVKPLPPA-KINARTACSECQIGAEVWTCLTCYKYNCGRFVNEHAMMHHLSSSHPMALSMADLSVWCYPCDSYVHNPALIGAKSAAHESKFGETMPS 955
BLAST of Histone deacetylase,putative vs. Ensembl Celegans
Match: hda-6 (Histone deacetylase 6 [Source:UniProtKB/Swiss-Prot;Acc:Q20296]) HSP 1 Score: 484.182 bits (1245), Expect = 3.100e-153 Identity = 282/780 (36.15%), Postives = 424/780 (54.36%), Query Frame = 2
Query: 296 HSNMWDNLYFERPDRLRVCYEGICETNLLEDC-IRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKENDQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMN-ERSIHPESPRRTQMIFEFLRDNSLLSRCKQLE-SRLASKDEIGLIHSPNYVESLGNI-CQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRS--ENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSL--------LGYPTNQIINFP--INKSGIEAIRKTLEYQKPYWKCLKFYE 2587
H N + E DR+ E + +T +LE C + EID+ + +H +S V+ + +++ T + ++D VF N+ + ++ ++ + A NGF ++RPPGHHA GFC+FNNV AA+ A + ++ILIVD DVHHG+ TQ FY+ +VLY SIHR+E G FWP L ES++D+IG+ +G GYN N+ LN+T T+SDYLSI ++LP+A +++P V+ISAGFD+ +G P G M + P ++H+ + L LA+GR++V+LEGGY + +V + L G AP +E + P +S ++ + + L W ++ P LR N+ + E Q E + +T ++ + H + E HPE P RT+ I + LR++ +L +C R+A+ +EI L+H+ +E L + + E+EFNSIY+ + + A + G +L +DE+ + N I+RPPGHHA + GFC FNNVA+AA YA ++ K++LI+DWDVHHGNGTQ F+ + NV+Y+S+HR+D G F+P S VG EG +VN+ ++ + D+EY AF ++MPI+++FNPDLV++SAGFDAA DPLG VTPE F MT L+SLA G++I LEGGYNL IS+ L L Q P I S I+ IR+ Q+ YW LK ++
Sbjct: 26 HENTVCPTHPESSDRILKIKEALTKTKILEKCTVLTNFLEIDDADLEVTHDKSMVKDLMESEKKTQEDINSQCEKYDSVFMTENSMKVAKDGVACVRDLTNRIMANEASNGFAVVRPPGHHADSVSPCGFCLFNNVAQAAEEAFFS-GAERILIVDLDVHHGHGTQRIFYDDKRVLYFSIHRHEHGLFWPHLPESDFDHIGSGKGLGYNANLALNETGCTDSDYLSIIFHVLLPLATQFDPHFVIISAGFDALLGDPLGGMCLTPDGYSHILYHLKSLAQGRMLVVLEGGYNHQISAVAVQRCVRVLLGYAPFSIELNEAPKESTVDSCVSLVSVLRHHWNCF------DYFPSRTSLRLAQWPIVNTKVIYNYDPTTRRADTGEIIQDELASTEFTASDVIPTENMETLIYFNEGDDAHFDLEEDNHPEKPARTRRILKTLRESGVLEKCVDRNCERIATNEEIRLVHTKKMLEHLRTTETMKDEELMEEAEKEFNSIYLTRDTLKVARKAVGAVLQSVDEIFEKDAGQRNALVIVRPPGHHASASKSSGFCIFNNVAVAAKYAQRRHKA--KRVLILDWDVHHGNGTQEIFYEDSNVMYMSIHRHDKGNFYPIGEPKDYSDVGEGAGEGMSVNVPFSGVQMGDNEYQMAFQRVIMPIAYQFNPDLVLISAGFDAAVDDPLGEYKVTPETFALMTYQLSSLAGGRIITVLEGGYNLTSISNSAQAVCEVLQNRSMLRRLREEKEQFATKPQKIESSCIKTIREVCAVQQKYWSILKGFQ 796 HSP 2 Score: 242.662 bits (618), Expect = 4.885e-66 Identity = 119/326 (36.50%), Postives = 197/326 (60.43%), Query Frame = 2
Query: 260 KTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEI-DNELIYYSHSQSHVQLIEDTQTMT-AIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRA--KNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKA 1225
+T ++E H ++ ++ + E+P R R + + E+ +LE C+ + I NE I H++ ++ + T+TM ++E + + ++ +T + + G+ ++ + + + A +N ++RPPGHHA S++SGFCIFNNV +AAKYAQ + +++LI+DWDVHHGN TQ FY S V+Y+SIHR++ GNF+P +Y +G G G ++N+P + M +++Y F +I+PIAY++NP+LVLISAGFD+A+ P G V P FA MT++L LA GR++ +LEGGY + S+ +S L ++
Sbjct: 426 ETLIYFNEGDDAHFDLEEDNHPEKPARTRRILKTLRESGVLEKCVDRNCERIATNEEIRLVHTKKMLEHLRTTETMKDEELMEEAEKEFNSIYLTRDTLKVARKAVGAVLQSVDEIFEKDAGQRNALVIVRPPGHHASASKSSGFCIFNNVAVAAKYAQRRHKAKRVLILDWDVHHGNGTQEIFYEDSNVMYMSIHRHDKGNFYPIGEPKDYSDVGEGAGEGMSVNVPFSGVQMGDNEYQMAFQRVIMPIAYQFNPDLVLISAGFDAAVDDPLGEYKVTPETFALMTYQLSSLAGGRIITVLEGGYNLTSISNSAQAVCEVLQNRS 751 HSP 3 Score: 112.464 bits (280), Expect = 7.471e-25 Identity = 54/111 (48.65%), Postives = 66/111 (59.46%), Query Frame = 2
Query: 3086 VYAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQVFCGRFVQAHMMQHFQNTRHAIVLSFVDLSSWCYECDSYVHNECLNHAKREAHIAKFGVPQPS 3418
+AV PL C HL +V+ P A +I+ +C+ C E W CLTCY+ CGRFV H M H ++ H + LS DLS WCY CDSYVHN L AK AH +KFG PS
Sbjct: 846 AHAVVPLATCPHLKEVKPLPPA-KINARTACSECQIGAEVWTCLTCYKYNCGRFVNEHAMMHHLSSSHPMALSMADLSVWCYPCDSYVHNPALIGAKSAAHESKFGETMPS 955
BLAST of Histone deacetylase,putative vs. Ensembl Celegans
Match: hda-6 (Histone deacetylase 6 [Source:UniProtKB/Swiss-Prot;Acc:Q20296]) HSP 1 Score: 481.871 bits (1239), Expect = 2.464e-152 Identity = 285/783 (36.40%), Postives = 427/783 (54.53%), Query Frame = 2
Query: 296 HSNMWDNLYFERPDRLRVCYEGICETNLLEDC-IRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVF---FDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKENDQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMN-ERSIHPESPRRTQMIFEFLRDNSLLSRCKQLE-SRLASKDEIGLIHSPNYVESLGNI-CQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRS--ENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSL--------LGYPTNQIINFP--INKSGIEAIRKTLEYQKPYWKCLKFYE 2587
H N + E DR+ E + +T +LE C + EID+ + +H +S V+ + +++ T + ++D VF F N+ K+A ++ ++ + A NGF ++RPPGHHA GFC+FNNV AA+ A + ++ILIVD DVHHG+ TQ FY+ +VLY SIHR+E G FWP L ES++D+IG+ +G GYN N+ LN+T T+SDYLSI ++LP+A +++P V+ISAGFD+ +G P G M + P ++H+ + L LA+GR++V+LEGGY + +V + L G AP +E + P +S ++ + + L W ++ P LR N+ + E Q E + +T ++ + H + E HPE P RT+ I + LR++ +L +C R+A+ +EI L+H+ +E L + + E+EFNSIY+ + + A + G +L +DE+ + N I+RPPGHHA + GFC FNNVA+AA YA ++ K++LI+DWDVHHGNGTQ F+ + NV+Y+S+HR+D G F+P S VG EG +VN+ ++ + D+EY AF ++MPI+++FNPDLV++SAGFDAA DPLG VTPE F MT L+SLA G++I LEGGYNL IS+ L L Q P I S I+ IR+ Q+ YW LK ++
Sbjct: 26 HENTVCPTHPESSDRILKIKEALTKTKILEKCTVLTNFLEIDDADLEVTHDKSMVKDLMESEKKTQEDINSQCEKYDSVFMTEFQNSMKVAK-DGVACVRDLTNRIMANEASNGFAVVRPPGHHADSVSPCGFCLFNNVAQAAEEAFFS-GAERILIVDLDVHHGHGTQRIFYDDKRVLYFSIHRHEHGLFWPHLPESDFDHIGSGKGLGYNANLALNETGCTDSDYLSIIFHVLLPLATQFDPHFVIISAGFDALLGDPLGGMCLTPDGYSHILYHLKSLAQGRMLVVLEGGYNHQISAVAVQRCVRVLLGYAPFSIELNEAPKESTVDSCVSLVSVLRHHWNCF------DYFPSRTSLRLAQWPIVNTKVIYNYDPTTRRADTGEIIQDELASTEFTASDVIPTENMETLIYFNEGDDAHFDLEEDNHPEKPARTRRILKTLRESGVLEKCVDRNCERIATNEEIRLVHTKKMLEHLRTTETMKDEELMEEAEKEFNSIYLTRDTLKVARKAVGAVLQSVDEIFEKDAGQRNALVIVRPPGHHASASKSSGFCIFNNVAVAAKYAQRRHKA--KRVLILDWDVHHGNGTQEIFYEDSNVMYMSIHRHDKGNFYPIGEPKDYSDVGEGAGEGMSVNVPFSGVQMGDNEYQMAFQRVIMPIAYQFNPDLVLISAGFDAAVDDPLGEYKVTPETFALMTYQLSSLAGGRIITVLEGGYNLTSISNSAQAVCEVLQNRSMLRRLREEKEQFATKPQKIESSCIKTIREVCAVQQKYWSILKGFQ 798 HSP 2 Score: 242.276 bits (617), Expect = 6.159e-66 Identity = 119/326 (36.50%), Postives = 197/326 (60.43%), Query Frame = 2
Query: 260 KTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEI-DNELIYYSHSQSHVQLIEDTQTMT-AIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRA--KNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKA 1225
+T ++E H ++ ++ + E+P R R + + E+ +LE C+ + I NE I H++ ++ + T+TM ++E + + ++ +T + + G+ ++ + + + A +N ++RPPGHHA S++SGFCIFNNV +AAKYAQ + +++LI+DWDVHHGN TQ FY S V+Y+SIHR++ GNF+P +Y +G G G ++N+P + M +++Y F +I+PIAY++NP+LVLISAGFD+A+ P G V P FA MT++L LA GR++ +LEGGY + S+ +S L ++
Sbjct: 428 ETLIYFNEGDDAHFDLEEDNHPEKPARTRRILKTLRESGVLEKCVDRNCERIATNEEIRLVHTKKMLEHLRTTETMKDEELMEEAEKEFNSIYLTRDTLKVARKAVGAVLQSVDEIFEKDAGQRNALVIVRPPGHHASASKSSGFCIFNNVAVAAKYAQRRHKAKRVLILDWDVHHGNGTQEIFYEDSNVMYMSIHRHDKGNFYPIGEPKDYSDVGEGAGEGMSVNVPFSGVQMGDNEYQMAFQRVIMPIAYQFNPDLVLISAGFDAAVDDPLGEYKVTPETFALMTYQLSSLAGGRIITVLEGGYNLTSISNSAQAVCEVLQNRS 753 HSP 3 Score: 112.464 bits (280), Expect = 8.087e-25 Identity = 54/111 (48.65%), Postives = 66/111 (59.46%), Query Frame = 2
Query: 3086 VYAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQVFCGRFVQAHMMQHFQNTRHAIVLSFVDLSSWCYECDSYVHNECLNHAKREAHIAKFGVPQPS 3418
+AV PL C HL +V+ P A +I+ +C+ C E W CLTCY+ CGRFV H M H ++ H + LS DLS WCY CDSYVHN L AK AH +KFG PS
Sbjct: 848 AHAVVPLATCPHLKEVKPLPPA-KINARTACSECQIGAEVWTCLTCYKYNCGRFVNEHAMMHHLSSSHPMALSMADLSVWCYPCDSYVHNPALIGAKSAAHESKFGETMPS 957
BLAST of Histone deacetylase,putative vs. Ensembl Fly
Match: HDAC6 (gene:FBgn0026428 transcript:FBtr0307384) HSP 1 Score: 662.144 bits (1707), Expect = 0.000e+0 Identity = 336/801 (41.95%), Postives = 488/801 (60.92%), Query Frame = 2
Query: 263 TAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQ-LKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGK-APPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVA---------DNHEPYPEYLRHLPESTWNSSKVP--KLPIEDN-----PNKCKENDQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMN-ERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLG--YPTNQIINFPINK-------SGIEAIRKTLEYQKPYWKCLKF 2581
TA +YDE M H +WD ++E P+R E E NL E C+ + ++ + I H++ H + +++T + + ++ELSS++D ++ +T S +++GSTIE++ ++ +A+NG +IRPPGHHAM++E +G+C FNNV +A ++A + Q+ILI+D+DVHHG TQ FYN +V+Y SIHR+E G+FWP L ES+Y IG+ G GYN N+PLN T MTN DYL+IF ++LP+A E+ PEL+++SAG+D+A+GCPEG M+V PAC+ H+ + L+ LA RV V+LEGGYC++SL + LTL +L G PP +E P + + + +C+ W+ L + D E LRH W P + P D P K N ++ LR + + K C+ YD +M H N + HPE P R Q I + D LL + KQL R A+ DE+ L H+ +V ++ + P H +NS+Y++ ++ A L+ GL+L +D V S +G +RPPGHHAE ++P GFC FNNVAIAA YA+ + ++++LIVDWDVHHGNGTQH F +N VLYISLHRY++G FFP DG+ VG GFNVNI WNK+ + D EY AF ++MPI++EFNP LV+VSAGFDAA GDPLGG VT E +G +T L++LA+G++I+ LEGGYN+N IS M+ C +LLG PT Q+ + K S +E++++ L+ Q+ +W+ L+F
Sbjct: 113 TALIYDESMSQHCCLWDKEHYECPERFTRVLERCRELNLTERCLELPSRSATKDEILRLHTEEHFERLKETSGIRDDERMEELSSRYDSIYIHPSTFELSLLASGSTIELVDHLVAGKAQNGMAIIRPPGHHAMKAEYNGYCFFNNVALATQHALDVHKLQRILIIDYDVHHGQGTQRFFYNDPRVVYFSIHRFEHGSFWPHLHESDYHAIGSGAGTGYNFNVPLNATGMTNGDYLAIFQQLLLPVALEFQPELIIVSAGYDAALGCPEGEMEVTPACYPHLLNPLLRLADARVAVVLEGGYCLDSLAEGAALTLRSLLGDPCPPLVETVPLPRAELAQALLSCIAVHRPHWRCLQLQQTYDCVELQDRDKEEDLHTVLRH-----WIGGPPPMDRYPTRDTAIPLPPEKLTSNAA---RLQVLRAETKLSVPSFKVCYAYDAQMLLHCNLNDTGHPEQPSRIQHIHKMHDDYGLLKQMKQLSPRAATTDEVCLAHTRAHVNTVRRLLGREPKELHDAAGIYNSVYLHPRTFDCATLAAGLVLQAVDSVLRGESRSGICNVRPPGHHAEQDHPHGFCIFNNVAIAAQYAIRDF--GLERVLIVDWDVHHGNGTQHIFESNPKVLYISLHRYEHGSFFPKGPDGNFDVVGKGAGRGFNVNIPWNKKGMGDLEYALAFQQLIMPIAYEFNPQLVLVSAGFDAAIGDPLGGCKVTAEGYGMLTHWLSALASGRIIVCLEGGYNVNSISYAMTMCTKTLLGDPVPTPQLGATALQKPPTVAFQSCVESLQQCLQVQRNHWRSLEF 903 HSP 2 Score: 283.878 bits (725), Expect = 1.572e-79 Identity = 160/463 (34.56%), Postives = 248/463 (53.56%), Query Frame = 2
Query: 236 ELRINFPN-KTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLE----KFDEP----CDSVKETIQNCLKFLHFFWKSLS-----------VNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKE--------------NDQLNHKIYELRTKNAFNNYPNKTC 1522
E +++ P+ K + YD QMLLH N+ D + E+P R++ ++ + LL+ ++ + + + +H+++HV + +L + + ++ V+ T + ++AG ++ + +VL +++G C +RPPGHHA + GFCIFNNV IAA+YA ++ +++LIVDWDVHHGN TQ+ F + KVLYIS+HRYE G+F+PK + N+D +G GRG+N+NIP NK M + +Y F +I+PIAYE+NP+LVL+SAGFD+AIG P G V + +TH L LA GR++V LEGGY + S+ ++ + TL G P + +P S E++Q CL+ W+SL V +N + LRHL S +++ D P+ E +D L L F YP KTC
Sbjct: 531 ETKLSVPSFKVCYAYDAQMLLHCNLNDTGHPEQPSRIQHIHKMHDDYGLLKQMKQLSPRAATTDEVCLAHTRAHVNTVRRLLGREPKELHDAAGIYNSVYLHPRTFDCATLAAGLVLQAVDSVLRGESRSGICNVRPPGHHAEQDHPHGFCIFNNVAIAAQYAIRDFGLERVLIVDWDVHHGNGTQHIFESNPKVLYISLHRYEHGSFFPKGPDGNFDVVGKGAGRGFNVNIPWNKKGMGDLEYALAFQQLIMPIAYEFNPQLVLVSAGFDAAIGDPLGGCKVTAEGYGMLTHWLSALASGRIIVCLEGGYNVNSISYAMTMCTKTLLGDPVPTPQLGATALQKPPTVAFQSCVESLQQCLQVQRNHWRSLEFVGRRLPRDPVVGENNNEDFLTASLRHLNISNDDATAAAGGLAGDRPDCGDERPSGSKPKVKVKTLSDYLAENKEALEQSEMFAVYPLKTC 993 HSP 3 Score: 245.743 bits (626), Expect = 1.150e-66 Identity = 130/366 (35.52%), Postives = 220/366 (60.11%), Query Frame = 2
Query: 1517 TCFVYDCRMENH--MNERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIY--HLFEE---EFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQII-NFPINKSGI-EAIRKTLEYQKPYWKCLKFYE 2587
T +YD M H + ++ H E P R + E R+ +L RC +L SR A+KDEI +H+ + E L +E+ I EE ++SIYI+ ++ +LL+ G + ++D + + +++NG AIIRPPGHHA G+CFFNNVA+A +AL + +++ILI+D+DVHHG GTQ F+ + V+Y S+HR+++G F+P + A+G G+N N+ N + + +Y++ F +++P++ EF P+L+IVSAG+DAA G P G + VTP C+ ++ L LA+ +V + LEGGY L+ +++ + + SLLG P ++ P+ ++ + +A+ + +P+W+CL+ +
Sbjct: 113 TALIYDESMSQHCCLWDKE-HYECPERFTRVLERCRELNLTERCLELPSRSATKDEILRLHTEEHFERL----KETSGIRDDERMEELSSRYDSIYIHPSTFELSLLASGSTIELVDHLVAGKAQNGMAIIRPPGHHAMKAEYNGYCFFNNVALATQHALDVHK--LQRILIIDYDVHHGQGTQRFFYNDPRVVYFSIHRFEHGSFWPHLHESDYHAIGSGAGTGYNFNVPLNATGMTNGDYLAIFQQLLLPVALEFQPELIIVSAGYDAALGCPEGEMEVTPACYPHLLNPLLRLADARVAVVLEGGYCLDSLAEGAALTLRSLLGDPCPPLVETVPLPRAELAQALLSCIAVHRPHWRCLQLQQ 471
BLAST of Histone deacetylase,putative vs. Ensembl Fly
Match: HDAC6 (gene:FBgn0026428 transcript:FBtr0301774) HSP 1 Score: 660.988 bits (1704), Expect = 0.000e+0 Identity = 336/801 (41.95%), Postives = 488/801 (60.92%), Query Frame = 2
Query: 263 TAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQ-LKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGK-APPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVA---------DNHEPYPEYLRHLPESTWNSSKVP--KLPIEDN-----PNKCKENDQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMN-ERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLG--YPTNQIINFPINK-------SGIEAIRKTLEYQKPYWKCLKF 2581
TA +YDE M H +WD ++E P+R E E NL E C+ + ++ + I H++ H + +++T + + ++ELSS++D ++ +T S +++GSTIE++ ++ +A+NG +IRPPGHHAM++E +G+C FNNV +A ++A + Q+ILI+D+DVHHG TQ FYN +V+Y SIHR+E G+FWP L ES+Y IG+ G GYN N+PLN T MTN DYL+IF ++LP+A E+ PEL+++SAG+D+A+GCPEG M+V PAC+ H+ + L+ LA RV V+LEGGYC++SL + LTL +L G PP +E P + + + +C+ W+ L + D E LRH W P + P D P K N ++ LR + + K C+ YD +M H N + HPE P R Q I + D LL + KQL R A+ DE+ L H+ +V ++ + P H +NS+Y++ ++ A L+ GL+L +D V S +G +RPPGHHAE ++P GFC FNNVAIAA YA+ + ++++LIVDWDVHHGNGTQH F +N VLYISLHRY++G FFP DG+ VG GFNVNI WNK+ + D EY AF ++MPI++EFNP LV+VSAGFDAA GDPLGG VT E +G +T L++LA+G++I+ LEGGYN+N IS M+ C +LLG PT Q+ + K S +E++++ L+ Q+ +W+ L+F
Sbjct: 31 TALIYDESMSQHCCLWDKEHYECPERFTRVLERCRELNLTERCLELPSRSATKDEILRLHTEEHFERLKETSGIRDDERMEELSSRYDSIYIHPSTFELSLLASGSTIELVDHLVAGKAQNGMAIIRPPGHHAMKAEYNGYCFFNNVALATQHALDVHKLQRILIIDYDVHHGQGTQRFFYNDPRVVYFSIHRFEHGSFWPHLHESDYHAIGSGAGTGYNFNVPLNATGMTNGDYLAIFQQLLLPVALEFQPELIIVSAGYDAALGCPEGEMEVTPACYPHLLNPLLRLADARVAVVLEGGYCLDSLAEGAALTLRSLLGDPCPPLVETVPLPRAELAQALLSCIAVHRPHWRCLQLQQTYDCVELQDRDKEEDLHTVLRH-----WIGGPPPMDRYPTRDTAIPLPPEKLTSNAA---RLQVLRAETKLSVPSFKVCYAYDAQMLLHCNLNDTGHPEQPSRIQHIHKMHDDYGLLKQMKQLSPRAATTDEVCLAHTRAHVNTVRRLLGREPKELHDAAGIYNSVYLHPRTFDCATLAAGLVLQAVDSVLRGESRSGICNVRPPGHHAEQDHPHGFCIFNNVAIAAQYAIRDF--GLERVLIVDWDVHHGNGTQHIFESNPKVLYISLHRYEHGSFFPKGPDGNFDVVGKGAGRGFNVNIPWNKKGMGDLEYALAFQQLIMPIAYEFNPQLVLVSAGFDAAIGDPLGGCKVTAEGYGMLTHWLSALASGRIIVCLEGGYNVNSISYAMTMCTKTLLGDPVPTPQLGATALQKPPTVAFQSCVESLQQCLQVQRNHWRSLEF 821 HSP 2 Score: 283.108 bits (723), Expect = 4.291e-80 Identity = 141/371 (38.01%), Postives = 222/371 (59.84%), Query Frame = 2
Query: 236 ELRINFPN-KTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLE----KFDEP----CDSVKETIQNCLKFLHFFWKSL 1321
E +++ P+ K + YD QMLLH N+ D + E+P R++ ++ + LL+ ++ + + + +H+++HV + +L + + ++ V+ T + ++AG ++ + +VL +++G C +RPPGHHA + GFCIFNNV IAA+YA ++ +++LIVDWDVHHGN TQ+ F + KVLYIS+HRYE G+F+PK + N+D +G GRG+N+NIP NK M + +Y F +I+PIAYE+NP+LVL+SAGFD+AIG P G V + +TH L LA GR++V LEGGY + S+ ++ + TL G P + +P S E++Q CL+ W+SL
Sbjct: 449 ETKLSVPSFKVCYAYDAQMLLHCNLNDTGHPEQPSRIQHIHKMHDDYGLLKQMKQLSPRAATTDEVCLAHTRAHVNTVRRLLGREPKELHDAAGIYNSVYLHPRTFDCATLAAGLVLQAVDSVLRGESRSGICNVRPPGHHAEQDHPHGFCIFNNVAIAAQYAIRDFGLERVLIVDWDVHHGNGTQHIFESNPKVLYISLHRYEHGSFFPKGPDGNFDVVGKGAGRGFNVNIPWNKKGMGDLEYALAFQQLIMPIAYEFNPQLVLVSAGFDAAIGDPLGGCKVTAEGYGMLTHWLSALASGRIIVCLEGGYNVNSISYAMTMCTKTLLGDPVPTPQLGATALQKPPTVAFQSCVESLQQCLQVQRNHWRSL 819 HSP 3 Score: 244.973 bits (624), Expect = 4.041e-67 Identity = 130/366 (35.52%), Postives = 220/366 (60.11%), Query Frame = 2
Query: 1517 TCFVYDCRMENH--MNERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIY--HLFEE---EFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQII-NFPINKSGI-EAIRKTLEYQKPYWKCLKFYE 2587
T +YD M H + ++ H E P R + E R+ +L RC +L SR A+KDEI +H+ + E L +E+ I EE ++SIYI+ ++ +LL+ G + ++D + + +++NG AIIRPPGHHA G+CFFNNVA+A +AL + +++ILI+D+DVHHG GTQ F+ + V+Y S+HR+++G F+P + A+G G+N N+ N + + +Y++ F +++P++ EF P+L+IVSAG+DAA G P G + VTP C+ ++ L LA+ +V + LEGGY L+ +++ + + SLLG P ++ P+ ++ + +A+ + +P+W+CL+ +
Sbjct: 31 TALIYDESMSQHCCLWDKE-HYECPERFTRVLERCRELNLTERCLELPSRSATKDEILRLHTEEHFERL----KETSGIRDDERMEELSSRYDSIYIHPSTFELSLLASGSTIELVDHLVAGKAQNGMAIIRPPGHHAMKAEYNGYCFFNNVALATQHALDVHK--LQRILIIDYDVHHGQGTQRFFYNDPRVVYFSIHRFEHGSFWPHLHESDYHAIGSGAGTGYNFNVPLNATGMTNGDYLAIFQQLLLPVALEFQPELIIVSAGYDAALGCPEGEMEVTPACYPHLLNPLLRLADARVAVVLEGGYCLDSLAEGAALTLRSLLGDPCPPLVETVPLPRAELAQALLSCIAVHRPHWRCLQLQQ 389
BLAST of Histone deacetylase,putative vs. Ensembl Fly
Match: HDAC6 (gene:FBgn0026428 transcript:FBtr0074009) HSP 1 Score: 660.603 bits (1703), Expect = 0.000e+0 Identity = 336/801 (41.95%), Postives = 488/801 (60.92%), Query Frame = 2
Query: 263 TAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQ-LKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGK-APPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVA---------DNHEPYPEYLRHLPESTWNSSKVP--KLPIEDN-----PNKCKENDQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMN-ERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLG--YPTNQIINFPINK-------SGIEAIRKTLEYQKPYWKCLKF 2581
TA +YDE M H +WD ++E P+R E E NL E C+ + ++ + I H++ H + +++T + + ++ELSS++D ++ +T S +++GSTIE++ ++ +A+NG +IRPPGHHAM++E +G+C FNNV +A ++A + Q+ILI+D+DVHHG TQ FYN +V+Y SIHR+E G+FWP L ES+Y IG+ G GYN N+PLN T MTN DYL+IF ++LP+A E+ PEL+++SAG+D+A+GCPEG M+V PAC+ H+ + L+ LA RV V+LEGGYC++SL + LTL +L G PP +E P + + + +C+ W+ L + D E LRH W P + P D P K N ++ LR + + K C+ YD +M H N + HPE P R Q I + D LL + KQL R A+ DE+ L H+ +V ++ + P H +NS+Y++ ++ A L+ GL+L +D V S +G +RPPGHHAE ++P GFC FNNVAIAA YA+ + ++++LIVDWDVHHGNGTQH F +N VLYISLHRY++G FFP DG+ VG GFNVNI WNK+ + D EY AF ++MPI++EFNP LV+VSAGFDAA GDPLGG VT E +G +T L++LA+G++I+ LEGGYN+N IS M+ C +LLG PT Q+ + K S +E++++ L+ Q+ +W+ L+F
Sbjct: 116 TALIYDESMSQHCCLWDKEHYECPERFTRVLERCRELNLTERCLELPSRSATKDEILRLHTEEHFERLKETSGIRDDERMEELSSRYDSIYIHPSTFELSLLASGSTIELVDHLVAGKAQNGMAIIRPPGHHAMKAEYNGYCFFNNVALATQHALDVHKLQRILIIDYDVHHGQGTQRFFYNDPRVVYFSIHRFEHGSFWPHLHESDYHAIGSGAGTGYNFNVPLNATGMTNGDYLAIFQQLLLPVALEFQPELIIVSAGYDAALGCPEGEMEVTPACYPHLLNPLLRLADARVAVVLEGGYCLDSLAEGAALTLRSLLGDPCPPLVETVPLPRAELAQALLSCIAVHRPHWRCLQLQQTYDCVELQDRDKEEDLHTVLRH-----WIGGPPPMDRYPTRDTAIPLPPEKLTSNAA---RLQVLRAETKLSVPSFKVCYAYDAQMLLHCNLNDTGHPEQPSRIQHIHKMHDDYGLLKQMKQLSPRAATTDEVCLAHTRAHVNTVRRLLGREPKELHDAAGIYNSVYLHPRTFDCATLAAGLVLQAVDSVLRGESRSGICNVRPPGHHAEQDHPHGFCIFNNVAIAAQYAIRDF--GLERVLIVDWDVHHGNGTQHIFESNPKVLYISLHRYEHGSFFPKGPDGNFDVVGKGAGRGFNVNIPWNKKGMGDLEYALAFQQLIMPIAYEFNPQLVLVSAGFDAAIGDPLGGCKVTAEGYGMLTHWLSALASGRIIVCLEGGYNVNSISYAMTMCTKTLLGDPVPTPQLGATALQKPPTVAFQSCVESLQQCLQVQRNHWRSLEF 906 HSP 2 Score: 283.493 bits (724), Expect = 6.952e-79 Identity = 160/463 (34.56%), Postives = 248/463 (53.56%), Query Frame = 2
Query: 236 ELRINFPN-KTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLE----KFDEP----CDSVKETIQNCLKFLHFFWKSLS-----------VNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKE--------------NDQLNHKIYELRTKNAFNNYPNKTC 1522
E +++ P+ K + YD QMLLH N+ D + E+P R++ ++ + LL+ ++ + + + +H+++HV + +L + + ++ V+ T + ++AG ++ + +VL +++G C +RPPGHHA + GFCIFNNV IAA+YA ++ +++LIVDWDVHHGN TQ+ F + KVLYIS+HRYE G+F+PK + N+D +G GRG+N+NIP NK M + +Y F +I+PIAYE+NP+LVL+SAGFD+AIG P G V + +TH L LA GR++V LEGGY + S+ ++ + TL G P + +P S E++Q CL+ W+SL V +N + LRHL S +++ D P+ E +D L L F YP KTC
Sbjct: 534 ETKLSVPSFKVCYAYDAQMLLHCNLNDTGHPEQPSRIQHIHKMHDDYGLLKQMKQLSPRAATTDEVCLAHTRAHVNTVRRLLGREPKELHDAAGIYNSVYLHPRTFDCATLAAGLVLQAVDSVLRGESRSGICNVRPPGHHAEQDHPHGFCIFNNVAIAAQYAIRDFGLERVLIVDWDVHHGNGTQHIFESNPKVLYISLHRYEHGSFFPKGPDGNFDVVGKGAGRGFNVNIPWNKKGMGDLEYALAFQQLIMPIAYEFNPQLVLVSAGFDAAIGDPLGGCKVTAEGYGMLTHWLSALASGRIIVCLEGGYNVNSISYAMTMCTKTLLGDPVPTPQLGATALQKPPTVAFQSCVESLQQCLQVQRNHWRSLEFVGRRLPRDPVVGENNNEDFLTASLRHLNISNDDATAAAGGLAGDRPDCGDERPSGSKPKVKVKTLSDYLAENKEALEQSEMFAVYPLKTC 996 HSP 3 Score: 244.973 bits (624), Expect = 3.761e-66 Identity = 130/366 (35.52%), Postives = 220/366 (60.11%), Query Frame = 2
Query: 1517 TCFVYDCRMENH--MNERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIY--HLFEE---EFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQII-NFPINKSGI-EAIRKTLEYQKPYWKCLKFYE 2587
T +YD M H + ++ H E P R + E R+ +L RC +L SR A+KDEI +H+ + E L +E+ I EE ++SIYI+ ++ +LL+ G + ++D + + +++NG AIIRPPGHHA G+CFFNNVA+A +AL + +++ILI+D+DVHHG GTQ F+ + V+Y S+HR+++G F+P + A+G G+N N+ N + + +Y++ F +++P++ EF P+L+IVSAG+DAA G P G + VTP C+ ++ L LA+ +V + LEGGY L+ +++ + + SLLG P ++ P+ ++ + +A+ + +P+W+CL+ +
Sbjct: 116 TALIYDESMSQHCCLWDKE-HYECPERFTRVLERCRELNLTERCLELPSRSATKDEILRLHTEEHFERL----KETSGIRDDERMEELSSRYDSIYIHPSTFELSLLASGSTIELVDHLVAGKAQNGMAIIRPPGHHAMKAEYNGYCFFNNVALATQHALDVHK--LQRILIIDYDVHHGQGTQRFFYNDPRVVYFSIHRFEHGSFWPHLHESDYHAIGSGAGTGYNFNVPLNATGMTNGDYLAIFQQLLLPVALEFQPELIIVSAGYDAALGCPEGEMEVTPACYPHLLNPLLRLADARVAVVLEGGYCLDSLAEGAALTLRSLLGDPCPPLVETVPLPRAELAQALLSCIAVHRPHWRCLQLQQ 474 HSP 4 Score: 96.6709 bits (239), Expect = 8.141e-20 Identity = 45/108 (41.67%), Postives = 61/108 (56.48%), Query Frame = 2
Query: 3086 VYAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQVFCGRFVQAHMMQHFQNTRHAIVLSFVDLSSWCYECDSYVHNECLNHAKREAHIAKFGVP 3409
++AV PL C HL ++ + +D A C++C ST ENW+CL+C V CGR+V AHM QH +H + +S DLS WCY C +YV + L H KF P
Sbjct: 987 MFAVYPLKTCPHLRLLRPEEAPRSLDSGAECSVCGSTGENWVCLSCRHVACGRYVNAHMEQHSVEEQHPLAMSTADLSVWCYACSAYVDHPRLYAYLNPLHEDKFQEP 1094
BLAST of Histone deacetylase,putative vs. Ensembl Fly
Match: HDAC6 (gene:FBgn0026428 transcript:FBtr0074008) HSP 1 Score: 660.603 bits (1703), Expect = 0.000e+0 Identity = 336/801 (41.95%), Postives = 488/801 (60.92%), Query Frame = 2
Query: 263 TAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQ-LKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGK-APPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVA---------DNHEPYPEYLRHLPESTWNSSKVP--KLPIEDN-----PNKCKENDQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMN-ERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLG--YPTNQIINFPINK-------SGIEAIRKTLEYQKPYWKCLKF 2581
TA +YDE M H +WD ++E P+R E E NL E C+ + ++ + I H++ H + +++T + + ++ELSS++D ++ +T S +++GSTIE++ ++ +A+NG +IRPPGHHAM++E +G+C FNNV +A ++A + Q+ILI+D+DVHHG TQ FYN +V+Y SIHR+E G+FWP L ES+Y IG+ G GYN N+PLN T MTN DYL+IF ++LP+A E+ PEL+++SAG+D+A+GCPEG M+V PAC+ H+ + L+ LA RV V+LEGGYC++SL + LTL +L G PP +E P + + + +C+ W+ L + D E LRH W P + P D P K N ++ LR + + K C+ YD +M H N + HPE P R Q I + D LL + KQL R A+ DE+ L H+ +V ++ + P H +NS+Y++ ++ A L+ GL+L +D V S +G +RPPGHHAE ++P GFC FNNVAIAA YA+ + ++++LIVDWDVHHGNGTQH F +N VLYISLHRY++G FFP DG+ VG GFNVNI WNK+ + D EY AF ++MPI++EFNP LV+VSAGFDAA GDPLGG VT E +G +T L++LA+G++I+ LEGGYN+N IS M+ C +LLG PT Q+ + K S +E++++ L+ Q+ +W+ L+F
Sbjct: 106 TALIYDESMSQHCCLWDKEHYECPERFTRVLERCRELNLTERCLELPSRSATKDEILRLHTEEHFERLKETSGIRDDERMEELSSRYDSIYIHPSTFELSLLASGSTIELVDHLVAGKAQNGMAIIRPPGHHAMKAEYNGYCFFNNVALATQHALDVHKLQRILIIDYDVHHGQGTQRFFYNDPRVVYFSIHRFEHGSFWPHLHESDYHAIGSGAGTGYNFNVPLNATGMTNGDYLAIFQQLLLPVALEFQPELIIVSAGYDAALGCPEGEMEVTPACYPHLLNPLLRLADARVAVVLEGGYCLDSLAEGAALTLRSLLGDPCPPLVETVPLPRAELAQALLSCIAVHRPHWRCLQLQQTYDCVELQDRDKEEDLHTVLRH-----WIGGPPPMDRYPTRDTAIPLPPEKLTSNAA---RLQVLRAETKLSVPSFKVCYAYDAQMLLHCNLNDTGHPEQPSRIQHIHKMHDDYGLLKQMKQLSPRAATTDEVCLAHTRAHVNTVRRLLGREPKELHDAAGIYNSVYLHPRTFDCATLAAGLVLQAVDSVLRGESRSGICNVRPPGHHAEQDHPHGFCIFNNVAIAAQYAIRDF--GLERVLIVDWDVHHGNGTQHIFESNPKVLYISLHRYEHGSFFPKGPDGNFDVVGKGAGRGFNVNIPWNKKGMGDLEYALAFQQLIMPIAYEFNPQLVLVSAGFDAAIGDPLGGCKVTAEGYGMLTHWLSALASGRIIVCLEGGYNVNSISYAMTMCTKTLLGDPVPTPQLGATALQKPPTVAFQSCVESLQQCLQVQRNHWRSLEF 896 HSP 2 Score: 283.878 bits (725), Expect = 5.543e-79 Identity = 160/463 (34.56%), Postives = 248/463 (53.56%), Query Frame = 2
Query: 236 ELRINFPN-KTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLE----KFDEP----CDSVKETIQNCLKFLHFFWKSLS-----------VNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKE--------------NDQLNHKIYELRTKNAFNNYPNKTC 1522
E +++ P+ K + YD QMLLH N+ D + E+P R++ ++ + LL+ ++ + + + +H+++HV + +L + + ++ V+ T + ++AG ++ + +VL +++G C +RPPGHHA + GFCIFNNV IAA+YA ++ +++LIVDWDVHHGN TQ+ F + KVLYIS+HRYE G+F+PK + N+D +G GRG+N+NIP NK M + +Y F +I+PIAYE+NP+LVL+SAGFD+AIG P G V + +TH L LA GR++V LEGGY + S+ ++ + TL G P + +P S E++Q CL+ W+SL V +N + LRHL S +++ D P+ E +D L L F YP KTC
Sbjct: 524 ETKLSVPSFKVCYAYDAQMLLHCNLNDTGHPEQPSRIQHIHKMHDDYGLLKQMKQLSPRAATTDEVCLAHTRAHVNTVRRLLGREPKELHDAAGIYNSVYLHPRTFDCATLAAGLVLQAVDSVLRGESRSGICNVRPPGHHAEQDHPHGFCIFNNVAIAAQYAIRDFGLERVLIVDWDVHHGNGTQHIFESNPKVLYISLHRYEHGSFFPKGPDGNFDVVGKGAGRGFNVNIPWNKKGMGDLEYALAFQQLIMPIAYEFNPQLVLVSAGFDAAIGDPLGGCKVTAEGYGMLTHWLSALASGRIIVCLEGGYNVNSISYAMTMCTKTLLGDPVPTPQLGATALQKPPTVAFQSCVESLQQCLQVQRNHWRSLEFVGRRLPRDPVVGENNNEDFLTASLRHLNISNDDATAAAGGLAGDRPDCGDERPSGSKPKVKVKTLSDYLAENKEALEQSEMFAVYPLKTC 986 HSP 3 Score: 244.973 bits (624), Expect = 3.644e-66 Identity = 130/366 (35.52%), Postives = 220/366 (60.11%), Query Frame = 2
Query: 1517 TCFVYDCRMENH--MNERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIY--HLFEE---EFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQII-NFPINKSGI-EAIRKTLEYQKPYWKCLKFYE 2587
T +YD M H + ++ H E P R + E R+ +L RC +L SR A+KDEI +H+ + E L +E+ I EE ++SIYI+ ++ +LL+ G + ++D + + +++NG AIIRPPGHHA G+CFFNNVA+A +AL + +++ILI+D+DVHHG GTQ F+ + V+Y S+HR+++G F+P + A+G G+N N+ N + + +Y++ F +++P++ EF P+L+IVSAG+DAA G P G + VTP C+ ++ L LA+ +V + LEGGY L+ +++ + + SLLG P ++ P+ ++ + +A+ + +P+W+CL+ +
Sbjct: 106 TALIYDESMSQHCCLWDKE-HYECPERFTRVLERCRELNLTERCLELPSRSATKDEILRLHTEEHFERL----KETSGIRDDERMEELSSRYDSIYIHPSTFELSLLASGSTIELVDHLVAGKAQNGMAIIRPPGHHAMKAEYNGYCFFNNVALATQHALDVHK--LQRILIIDYDVHHGQGTQRFFYNDPRVVYFSIHRFEHGSFWPHLHESDYHAIGSGAGTGYNFNVPLNATGMTNGDYLAIFQQLLLPVALEFQPELIIVSAGYDAALGCPEGEMEVTPACYPHLLNPLLRLADARVAVVLEGGYCLDSLAEGAALTLRSLLGDPCPPLVETVPLPRAELAQALLSCIAVHRPHWRCLQLQQ 464 HSP 4 Score: 96.6709 bits (239), Expect = 8.969e-20 Identity = 45/108 (41.67%), Postives = 61/108 (56.48%), Query Frame = 2
Query: 3086 VYAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQVFCGRFVQAHMMQHFQNTRHAIVLSFVDLSSWCYECDSYVHNECLNHAKREAHIAKFGVP 3409
++AV PL C HL ++ + +D A C++C ST ENW+CL+C V CGR+V AHM QH +H + +S DLS WCY C +YV + L H KF P
Sbjct: 977 MFAVYPLKTCPHLRLLRPEEAPRSLDSGAECSVCGSTGENWVCLSCRHVACGRYVNAHMEQHSVEEQHPLAMSTADLSVWCYACSAYVDHPRLYAYLNPLHEDKFQEP 1084
BLAST of Histone deacetylase,putative vs. Ensembl Fly
Match: HDAC6 (gene:FBgn0026428 transcript:FBtr0074010) HSP 1 Score: 660.218 bits (1702), Expect = 0.000e+0 Identity = 336/801 (41.95%), Postives = 488/801 (60.92%), Query Frame = 2
Query: 263 TAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQ-LKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGK-APPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVA---------DNHEPYPEYLRHLPESTWNSSKVP--KLPIEDN-----PNKCKENDQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMN-ERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLG--YPTNQIINFPINK-------SGIEAIRKTLEYQKPYWKCLKF 2581
TA +YDE M H +WD ++E P+R E E NL E C+ + ++ + I H++ H + +++T + + ++ELSS++D ++ +T S +++GSTIE++ ++ +A+NG +IRPPGHHAM++E +G+C FNNV +A ++A + Q+ILI+D+DVHHG TQ FYN +V+Y SIHR+E G+FWP L ES+Y IG+ G GYN N+PLN T MTN DYL+IF ++LP+A E+ PEL+++SAG+D+A+GCPEG M+V PAC+ H+ + L+ LA RV V+LEGGYC++SL + LTL +L G PP +E P + + + +C+ W+ L + D E LRH W P + P D P K N ++ LR + + K C+ YD +M H N + HPE P R Q I + D LL + KQL R A+ DE+ L H+ +V ++ + P H +NS+Y++ ++ A L+ GL+L +D V S +G +RPPGHHAE ++P GFC FNNVAIAA YA+ + ++++LIVDWDVHHGNGTQH F +N VLYISLHRY++G FFP DG+ VG GFNVNI WNK+ + D EY AF ++MPI++EFNP LV+VSAGFDAA GDPLGG VT E +G +T L++LA+G++I+ LEGGYN+N IS M+ C +LLG PT Q+ + K S +E++++ L+ Q+ +W+ L+F
Sbjct: 113 TALIYDESMSQHCCLWDKEHYECPERFTRVLERCRELNLTERCLELPSRSATKDEILRLHTEEHFERLKETSGIRDDERMEELSSRYDSIYIHPSTFELSLLASGSTIELVDHLVAGKAQNGMAIIRPPGHHAMKAEYNGYCFFNNVALATQHALDVHKLQRILIIDYDVHHGQGTQRFFYNDPRVVYFSIHRFEHGSFWPHLHESDYHAIGSGAGTGYNFNVPLNATGMTNGDYLAIFQQLLLPVALEFQPELIIVSAGYDAALGCPEGEMEVTPACYPHLLNPLLRLADARVAVVLEGGYCLDSLAEGAALTLRSLLGDPCPPLVETVPLPRAELAQALLSCIAVHRPHWRCLQLQQTYDCVELQDRDKEEDLHTVLRH-----WIGGPPPMDRYPTRDTAIPLPPEKLTSNAA---RLQVLRAETKLSVPSFKVCYAYDAQMLLHCNLNDTGHPEQPSRIQHIHKMHDDYGLLKQMKQLSPRAATTDEVCLAHTRAHVNTVRRLLGREPKELHDAAGIYNSVYLHPRTFDCATLAAGLVLQAVDSVLRGESRSGICNVRPPGHHAEQDHPHGFCIFNNVAIAAQYAIRDF--GLERVLIVDWDVHHGNGTQHIFESNPKVLYISLHRYEHGSFFPKGPDGNFDVVGKGAGRGFNVNIPWNKKGMGDLEYALAFQQLIMPIAYEFNPQLVLVSAGFDAAIGDPLGGCKVTAEGYGMLTHWLSALASGRIIVCLEGGYNVNSISYAMTMCTKTLLGDPVPTPQLGATALQKPPTVAFQSCVESLQQCLQVQRNHWRSLEF 903 HSP 2 Score: 283.493 bits (724), Expect = 7.015e-79 Identity = 160/463 (34.56%), Postives = 248/463 (53.56%), Query Frame = 2
Query: 236 ELRINFPN-KTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLE----KFDEP----CDSVKETIQNCLKFLHFFWKSLS-----------VNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKE--------------NDQLNHKIYELRTKNAFNNYPNKTC 1522
E +++ P+ K + YD QMLLH N+ D + E+P R++ ++ + LL+ ++ + + + +H+++HV + +L + + ++ V+ T + ++AG ++ + +VL +++G C +RPPGHHA + GFCIFNNV IAA+YA ++ +++LIVDWDVHHGN TQ+ F + KVLYIS+HRYE G+F+PK + N+D +G GRG+N+NIP NK M + +Y F +I+PIAYE+NP+LVL+SAGFD+AIG P G V + +TH L LA GR++V LEGGY + S+ ++ + TL G P + +P S E++Q CL+ W+SL V +N + LRHL S +++ D P+ E +D L L F YP KTC
Sbjct: 531 ETKLSVPSFKVCYAYDAQMLLHCNLNDTGHPEQPSRIQHIHKMHDDYGLLKQMKQLSPRAATTDEVCLAHTRAHVNTVRRLLGREPKELHDAAGIYNSVYLHPRTFDCATLAAGLVLQAVDSVLRGESRSGICNVRPPGHHAEQDHPHGFCIFNNVAIAAQYAIRDFGLERVLIVDWDVHHGNGTQHIFESNPKVLYISLHRYEHGSFFPKGPDGNFDVVGKGAGRGFNVNIPWNKKGMGDLEYALAFQQLIMPIAYEFNPQLVLVSAGFDAAIGDPLGGCKVTAEGYGMLTHWLSALASGRIIVCLEGGYNVNSISYAMTMCTKTLLGDPVPTPQLGATALQKPPTVAFQSCVESLQQCLQVQRNHWRSLEFVGRRLPRDPVVGENNNEDFLTASLRHLNISNDDATAAAGGLAGDRPDCGDERPSGSKPKVKVKTLSDYLAENKEALEQSEMFAVYPLKTC 993 HSP 3 Score: 244.973 bits (624), Expect = 4.193e-66 Identity = 130/366 (35.52%), Postives = 220/366 (60.11%), Query Frame = 2
Query: 1517 TCFVYDCRMENH--MNERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIY--HLFEE---EFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQII-NFPINKSGI-EAIRKTLEYQKPYWKCLKFYE 2587
T +YD M H + ++ H E P R + E R+ +L RC +L SR A+KDEI +H+ + E L +E+ I EE ++SIYI+ ++ +LL+ G + ++D + + +++NG AIIRPPGHHA G+CFFNNVA+A +AL + +++ILI+D+DVHHG GTQ F+ + V+Y S+HR+++G F+P + A+G G+N N+ N + + +Y++ F +++P++ EF P+L+IVSAG+DAA G P G + VTP C+ ++ L LA+ +V + LEGGY L+ +++ + + SLLG P ++ P+ ++ + +A+ + +P+W+CL+ +
Sbjct: 113 TALIYDESMSQHCCLWDKE-HYECPERFTRVLERCRELNLTERCLELPSRSATKDEILRLHTEEHFERL----KETSGIRDDERMEELSSRYDSIYIHPSTFELSLLASGSTIELVDHLVAGKAQNGMAIIRPPGHHAMKAEYNGYCFFNNVALATQHALDVHK--LQRILIIDYDVHHGQGTQRFFYNDPRVVYFSIHRFEHGSFWPHLHESDYHAIGSGAGTGYNFNVPLNATGMTNGDYLAIFQQLLLPVALEFQPELIIVSAGYDAALGCPEGEMEVTPACYPHLLNPLLRLADARVAVVLEGGYCLDSLAEGAALTLRSLLGDPCPPLVETVPLPRAELAQALLSCIAVHRPHWRCLQLQQ 471 HSP 4 Score: 96.6709 bits (239), Expect = 9.312e-20 Identity = 45/108 (41.67%), Postives = 61/108 (56.48%), Query Frame = 2
Query: 3086 VYAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQVFCGRFVQAHMMQHFQNTRHAIVLSFVDLSSWCYECDSYVHNECLNHAKREAHIAKFGVP 3409
++AV PL C HL ++ + +D A C++C ST ENW+CL+C V CGR+V AHM QH +H + +S DLS WCY C +YV + L H KF P
Sbjct: 984 MFAVYPLKTCPHLRLLRPEEAPRSLDSGAECSVCGSTGENWVCLSCRHVACGRYVNAHMEQHSVEEQHPLAMSTADLSVWCYACSAYVDHPRLYAYLNPLHEDKFQEP 1091
BLAST of Histone deacetylase,putative vs. Ensembl Zebrafish
Match: hdac6 (histone deacetylase 6 [Source:ZFIN;Acc:ZDB-GENE-030131-3232]) HSP 1 Score: 733.791 bits (1893), Expect = 0.000e+0 Identity = 410/1081 (37.93%), Postives = 586/1081 (54.21%), Query Frame = 2
Query: 263 TAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKENDQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMNE-RSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINF-PINKSGIEAIRKTLEYQKPYWKCLKFYEPLVVTYT----------------EISPNQTNPA-----ALDNIVQIDTNTLAESVRQLGIVEVTFQTEQSIEETLSQPRNDTFITEPN---------SSNPIIHLPPIVSSDNAVEVPATTSINSTTHATQNISANFLSVDQSSGATPVSANVSRVINE--GNSVGLVLQDIMNLSGVSNSDIHHFLGLTSNDPLPERVYAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQVFCGRFVQAHMMQHFQNTRHAIVLSFVDLSSWCYECDSYVHNECLNHAKREAHIAKFG 3403
T VY + +WD + E P R+ E + LL C++++A+ + + + H++ +V+L++ TQ MT +LK L+ ++D V+ ++ +S GS ++++ V+ + +NGF + RPPGHHA + +GFC+FNN+ IAA+YAQ + Q++LIVDWDVHHG QY F VLY S+HRYEDG+FWP L+ES+ +G+ G+GYNIN+P NK M + DY++ F ++LP+AYE+ P+LVL++AGFD+ IG P+G M V P CF+ +TH L +A+GR+V+ LEGGY ++S + V ++ +L G P L PC+S ++I + L+ FWKSL P E + LP KV PI T VYD RM H N S HPE P+R IF + LLSRC ++ +RLA+++E+ L HS ++ + + P + +E+NSI+I+ SY ALL+ G N + + + N AI+RPPGHHAE + GFCFFN A+ A YA + ES++ +LIVDWDVHHGNGTQH F + +VLYISLHRY++G FFP S D + VG G+NVNI WN + D EY++AF ++VMPI+ EF P+LV+VSAGFDAARGDPLGG VTPE + ++T L SLA G+V++ LEGGYNL IS+ MS C S LLG + + P+ S +I L P+W L+ P + + + SP Q+ P+ A Q + L + L + T + R +PN S +P+ P + + +V A T ++IS ++ D S+ V S V+ GN+V VL+ + G +D+ + +Y V PL WC HL V+ P A IDV C C ENW+CL CY+V CGR+V HM+ H Q + H +VLSF DLS WCY C+SYVHN+ L+ AK AH+ KFG
Sbjct: 63 TGLVYVDAFTRFHCLWDASHPECPARVSTVMEMLETEGLLGRCVQVEARAVTEDELLLVHTKEYVELMKSTQNMTEEELKTLAEKYDSVYLHPGFFSSACLSVGSVLQLVDKVMTSQLRNGFSINRPPGHHAQADKMNGFCMFNNLAIAARYAQKRHRVQRVLIVDWDVHHGQGIQYIFEEDPSVLYFSVHRYEDGSFWPHLKESDSSSVGSGAGQGYNINLPWNKVGMESGDYITAFQQLLLPVAYEFQPQLVLVAAGFDAVIGDPKGGMQVSPECFSILTHMLKGVAQGRLVLALEGGYNLQSTAEGVCASMRSLLGDPCPHLPSSGAPCESALKSISKTISDLYPFWKSLQTFEGG---PLSE-VSPLPAPVCAEVKVSS-PI--------------------------------TGLVYDQRMMLHHNMWDSHHPELPQRISRIFSRHEELRLLSRCHRIPARLATEEELALCHSSKHISIIKSSEHMKPRDLNRLGDEYNSIFISNESYTCALLAAGSCFNSAQAILTGQVRNAVAIVRPPGHHAEKDTACGFCFFNTAALTARYAQSITRESLR-VLIVDWDVHHGNGTQHIFEEDDSVLYISLHRYEDGAFFPNSEDANYDKVGLGKGRGYNVNIPWNGGKMGDPEYMAAFHHLVMPIAREFAPELVLVSAGFDAARGDPLGGFQVTPEGYAHLTHQLMSLAAGRVLIILEGGYNLTSISESMSMCTSMLLGDSPPSLDHLTPLKTSATVSINNVLRAHAPFWSSLRVNIPESLRLSLPSPKPKGKCTPGGKGKKSPRQSTPSQSPGQATHRPDQSGFDELTADLLSLNLNTSTSSNTSPESVAVGGARRK---VKPNTHRVSAGLESESPLKLNPEKAGAGDDTDVKAET-------PNRSISEPVVTCDSSA----VKDQESLVLEAAGGNTVQSVLERVF---GAQATDV-------------DTMYVVDPLPWCPHLESVRPVP-AGGIDVFQPCEECGGEAENWICLFCYKVLCGRYVNQHMVTHGQESGHPVVLSFADLSVWCYACESYVHNKVLHEAKNAAHLVKFG 1074 HSP 2 Score: 328.946 bits (842), Expect = 1.151e-94 Identity = 157/379 (41.42%), Postives = 231/379 (60.95%), Query Frame = 2
Query: 236 ELRINFPNKTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQ-LNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHEPYPEYLR 1369
E++++ P T VYD++M+LH NMWD+ + E P R+ + E LL C RI A+ E + HS H+ +I+ ++ M L L +++ +F N + + ++AGS +A+L + +N ++RPPGHHA + A GFC FN + A+YAQ + + ++LIVDWDVHHGN TQ+ F VLYIS+HRYEDG F+P ++NYD +G +GRGYN+NIP N M + +Y++ FH +++PIA E+ PELVL+SAGFD+A G P G V P +AH+TH+LM LA GRV+++LEGGY + S+ +S+ + + L G +PP L+ S +I N L+ FW SL VN+ PE LR
Sbjct: 436 EVKVSSP-ITGLVYDQRMMLHHNMWDSHHPELPQRISRIFSRHEELRLLSRCHRIPARLATEEELALCHSSKHISIIKSSEHMKPRDLNRLGDEYNSIFISNESYTCALLAAGSCFNSAQAILTGQVRNAVAIVRPPGHHAEKDTACGFCFFNTAALTARYAQSITRESLRVLIVDWDVHHGNGTQHIFEEDDSVLYISLHRYEDGAFFPNSEDANYDKVGLGKGRGYNVNIPWNGGKMGDPEYMAAFHHLVMPIAREFAPELVLVSAGFDAARGDPLGGFQVTPEGYAHLTHQLMSLAAGRVLIILEGGYNLTSISESMSMCTSMLLGDSPPSLDHLTPLKTSATVSINNVLRAHAPFWSSLRVNI-------PESLR 806 HSP 3 Score: 306.605 bits (784), Expect = 5.866e-87 Identity = 157/422 (37.20%), Postives = 254/422 (60.19%), Query Frame = 2
Query: 1367 RHLPESTWNSSKVPKLPIEDNPNKCKENDQLNHKIYELRTKNAFNNYPNKTCFVY-DCRMENHMNERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINFPIN-KSGIEAIRKTLEYQKPYWKCLKFYE--PLVVTYTEISP 2620
R PE+ N + + + ++ K +++++++ L + + T VY D H + HPE P R + E L LL RC Q+E+R ++DE+ L+H+ YVE + + + E+++S+Y++ + SA LS G +L ++D+V + + NGF+I RPPGHHA+ + GFC FNN+AIAA YA ++ ++++LIVDWDVHHG G Q+ F + +VLY S+HRY++G F+P + S+VG +G+N+N+ WNK + +YI+AF +++P+++EF P LV+V+AGFDA GDP GG+ V+PECF +T ML +A G+++LALEGGYNL ++ + + SLLG P + + +S +++I KT+ P+WK L+ +E PL +E+SP
Sbjct: 15 RGTPETKNNKKNLQEARRKGRMDRSKAEEEMSNELQNLDVQG--KSKATGTGLVYVDAFTRFHCLWDASHPECPARVSTVMEMLETEGLLGRCVQVEARAVTEDELLLVHTKEYVELMKSTQNMTEEELKTLAEKYDSVYLHPGFFSSACLSVGSVLQLVDKVMTSQLRNGFSINRPPGHHAQADKMNGFCMFNNLAIAARYAQKRHR--VQRVLIVDWDVHHGQGIQYIFEEDPSVLYFSVHRYEDGSFWPHLKESDSSSVGSGAGQGYNINLPWNKVGMESGDYITAFQQLLLPVAYEFQPQLVLVAAGFDAVIGDPKGGMQVSPECFSILTHMLKGVAQGRLVLALEGGYNLQSTAEGVCASMRSLLGDPCPHLPSSGAPCESALKSISKTISDLYPFWKSLQTFEGGPL----SEVSP 428
BLAST of Histone deacetylase,putative vs. Ensembl Zebrafish
Match: hdac6 (histone deacetylase 6 [Source:ZFIN;Acc:ZDB-GENE-030131-3232]) HSP 1 Score: 733.791 bits (1893), Expect = 0.000e+0 Identity = 410/1081 (37.93%), Postives = 586/1081 (54.21%), Query Frame = 2
Query: 263 TAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKENDQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMNE-RSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINF-PINKSGIEAIRKTLEYQKPYWKCLKFYEPLVVTYT----------------EISPNQTNPA-----ALDNIVQIDTNTLAESVRQLGIVEVTFQTEQSIEETLSQPRNDTFITEPN---------SSNPIIHLPPIVSSDNAVEVPATTSINSTTHATQNISANFLSVDQSSGATPVSANVSRVINE--GNSVGLVLQDIMNLSGVSNSDIHHFLGLTSNDPLPERVYAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQVFCGRFVQAHMMQHFQNTRHAIVLSFVDLSSWCYECDSYVHNECLNHAKREAHIAKFG 3403
T VY + +WD + E P R+ E + LL C++++A+ + + + H++ +V+L++ TQ MT +LK L+ ++D V+ ++ +S GS ++++ V+ + +NGF + RPPGHHA + +GFC+FNN+ IAA+YAQ + Q++LIVDWDVHHG QY F VLY S+HRYEDG+FWP L+ES+ +G+ G+GYNIN+P NK M + DY++ F ++LP+AYE+ P+LVL++AGFD+ IG P+G M V P CF+ +TH L +A+GR+V+ LEGGY ++S + V ++ +L G P L PC+S ++I + L+ FWKSL P E + LP KV PI T VYD RM H N S HPE P+R IF + LLSRC ++ +RLA+++E+ L HS ++ + + P + +E+NSI+I+ SY ALL+ G N + + + N AI+RPPGHHAE + GFCFFN A+ A YA + ES++ +LIVDWDVHHGNGTQH F + +VLYISLHRY++G FFP S D + VG G+NVNI WN + D EY++AF ++VMPI+ EF P+LV+VSAGFDAARGDPLGG VTPE + ++T L SLA G+V++ LEGGYNL IS+ MS C S LLG + + P+ S +I L P+W L+ P + + + SP Q+ P+ A Q + L + L + T + R +PN S +P+ P + + +V A T ++IS ++ D S+ V S V+ GN+V VL+ + G +D+ + +Y V PL WC HL V+ P A IDV C C ENW+CL CY+V CGR+V HM+ H Q + H +VLSF DLS WCY C+SYVHN+ L+ AK AH+ KFG
Sbjct: 63 TGLVYVDAFTRFHCLWDASHPECPARVSTVMEMLETEGLLGRCVQVEARAVTEDELLLVHTKEYVELMKSTQNMTEEELKTLAEKYDSVYLHPGFFSSACLSVGSVLQLVDKVMTSQLRNGFSINRPPGHHAQADKMNGFCMFNNLAIAARYAQKRHRVQRVLIVDWDVHHGQGIQYIFEEDPSVLYFSVHRYEDGSFWPHLKESDSSSVGSGAGQGYNINLPWNKVGMESGDYITAFQQLLLPVAYEFQPQLVLVAAGFDAVIGDPKGGMQVSPECFSILTHMLKGVAQGRLVLALEGGYNLQSTAEGVCASMRSLLGDPCPHLPSSGAPCESALKSISKTISDLYPFWKSLQTFEGG---PLSE-VSPLPAPVCAEVKVSS-PI--------------------------------TGLVYDQRMMLHHNMWDSHHPELPQRISRIFSRHEELRLLSRCHRIPARLATEEELALCHSSKHISIIKSSEHMKPRDLNRLGDEYNSIFISNESYTCALLAAGSCFNSAQAILTGQVRNAVAIVRPPGHHAEKDTACGFCFFNTAALTARYAQSITRESLR-VLIVDWDVHHGNGTQHIFEEDDSVLYISLHRYEDGAFFPNSEDANYDKVGLGKGRGYNVNIPWNGGKMGDPEYMAAFHHLVMPIAREFAPELVLVSAGFDAARGDPLGGFQVTPEGYAHLTHQLMSLAAGRVLIILEGGYNLTSISESMSMCTSMLLGDSPPSLDHLTPLKTSATVSINNVLRAHAPFWSSLRVNIPESLRLSLPSPKPKGKCTPGGKGKKSPRQSTPSQSPGQATHRPDQSGFDELTADLLSLNLNTSTSSNTSPESVAVGGARRK---VKPNTHRVSAGLESESPLKLNPEKAGAGDDTDVKAET-------PNRSISEPVVTCDSSA----VKDQESLVLEAAGGNTVQSVLERVF---GAQATDV-------------DTMYVVDPLPWCPHLESVRPVP-AGGIDVFQPCEECGGEAENWICLFCYKVLCGRYVNQHMVTHGQESGHPVVLSFADLSVWCYACESYVHNKVLHEAKNAAHLVKFG 1074 HSP 2 Score: 328.946 bits (842), Expect = 1.151e-94 Identity = 157/379 (41.42%), Postives = 231/379 (60.95%), Query Frame = 2
Query: 236 ELRINFPNKTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQ-LNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHEPYPEYLR 1369
E++++ P T VYD++M+LH NMWD+ + E P R+ + E LL C RI A+ E + HS H+ +I+ ++ M L L +++ +F N + + ++AGS +A+L + +N ++RPPGHHA + A GFC FN + A+YAQ + + ++LIVDWDVHHGN TQ+ F VLYIS+HRYEDG F+P ++NYD +G +GRGYN+NIP N M + +Y++ FH +++PIA E+ PELVL+SAGFD+A G P G V P +AH+TH+LM LA GRV+++LEGGY + S+ +S+ + + L G +PP L+ S +I N L+ FW SL VN+ PE LR
Sbjct: 436 EVKVSSP-ITGLVYDQRMMLHHNMWDSHHPELPQRISRIFSRHEELRLLSRCHRIPARLATEEELALCHSSKHISIIKSSEHMKPRDLNRLGDEYNSIFISNESYTCALLAAGSCFNSAQAILTGQVRNAVAIVRPPGHHAEKDTACGFCFFNTAALTARYAQSITRESLRVLIVDWDVHHGNGTQHIFEEDDSVLYISLHRYEDGAFFPNSEDANYDKVGLGKGRGYNVNIPWNGGKMGDPEYMAAFHHLVMPIAREFAPELVLVSAGFDAARGDPLGGFQVTPEGYAHLTHQLMSLAAGRVLIILEGGYNLTSISESMSMCTSMLLGDSPPSLDHLTPLKTSATVSINNVLRAHAPFWSSLRVNI-------PESLR 806 HSP 3 Score: 306.605 bits (784), Expect = 5.866e-87 Identity = 157/422 (37.20%), Postives = 254/422 (60.19%), Query Frame = 2
Query: 1367 RHLPESTWNSSKVPKLPIEDNPNKCKENDQLNHKIYELRTKNAFNNYPNKTCFVY-DCRMENHMNERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINFPIN-KSGIEAIRKTLEYQKPYWKCLKFYE--PLVVTYTEISP 2620
R PE+ N + + + ++ K +++++++ L + + T VY D H + HPE P R + E L LL RC Q+E+R ++DE+ L+H+ YVE + + + E+++S+Y++ + SA LS G +L ++D+V + + NGF+I RPPGHHA+ + GFC FNN+AIAA YA ++ ++++LIVDWDVHHG G Q+ F + +VLY S+HRY++G F+P + S+VG +G+N+N+ WNK + +YI+AF +++P+++EF P LV+V+AGFDA GDP GG+ V+PECF +T ML +A G+++LALEGGYNL ++ + + SLLG P + + +S +++I KT+ P+WK L+ +E PL +E+SP
Sbjct: 15 RGTPETKNNKKNLQEARRKGRMDRSKAEEEMSNELQNLDVQG--KSKATGTGLVYVDAFTRFHCLWDASHPECPARVSTVMEMLETEGLLGRCVQVEARAVTEDELLLVHTKEYVELMKSTQNMTEEELKTLAEKYDSVYLHPGFFSSACLSVGSVLQLVDKVMTSQLRNGFSINRPPGHHAQADKMNGFCMFNNLAIAARYAQKRHR--VQRVLIVDWDVHHGQGIQYIFEEDPSVLYFSVHRYEDGSFWPHLKESDSSSVGSGAGQGYNINLPWNKVGMESGDYITAFQQLLLPVAYEFQPQLVLVAAGFDAVIGDPKGGMQVSPECFSILTHMLKGVAQGRLVLALEGGYNLQSTAEGVCASMRSLLGDPCPHLPSSGAPCESALKSISKTISDLYPFWKSLQTFEGGPL----SEVSP 428
BLAST of Histone deacetylase,putative vs. Ensembl Zebrafish
Match: hdac10 (histone deacetylase 10 [Source:NCBI gene;Acc:327253]) HSP 1 Score: 330.872 bits (847), Expect = 5.148e-99 Identity = 164/393 (41.73%), Postives = 235/393 (59.80%), Query Frame = 2
Query: 263 TAFVYDEQMLLHSNMWDN--LYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPN 1435
+A ++DE+M + +W + E P+RL V YE + L + C + ++ + I +HS+ +++ ++ T M +L S +++ V+F N + ++AG+T++++ +V+ +NG L+RPPGHH+ S A+GFC+FNNV IAA YA+ NY+ +ILIVDWDVHHG QY F VLY S HRYE +FWP L ES+Y +G +G G+NIN+P NK MTNSDYL+ F ++LP+AYE++PELV++SAGFDSAIG PEG M P FAH+TH LM LA G++ V+LEGGY + SL SV T+ +L G P++ CDS E+IQN +W S +HL +S N PK P D N
Sbjct: 5 SALIFDEEMSRYKLLWTDPACEIEVPERLTVSYEALRTHGLAQRCKAVPVRQATEQEILLAHSEEYLEAVKQTPGMNVEELMAFSKKYNDVYFHQNIYHCAKLAAGATLQLVDSVMKREVRNGMALVRPPGHHSQRSAANGFCVFNNVAIAALYAKKNYNLNRILIVDWDVHHGQGIQYCFEEDPSVLYFSWHRYEHQSFWPNLPESDYSSVGKGKGSGFNINLPWNKVGMTNSDYLAAFFHVLLPVAYEFDPELVIVSAGFDSAIGDPEGEMCALPEIFAHLTHLLMPLAAGKMCVVLEGGYNLTSLGQSVCQTVHSLLGDPTPRISGLGTACDSALESIQNVRNVQSSYWSS---------------FKHLAQSETN----PKRPRLDATN 378 HSP 2 Score: 276.559 bits (706), Expect = 2.071e-79 Identity = 139/335 (41.49%), Postives = 203/335 (60.60%), Query Frame = 2
Query: 1577 ESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINFPIN-KSGIEAIRKTLEYQKPYWKCLK 2578
E P R + +E LR + L RCK + R A++ EI L HS Y+E++ + F +++N +Y +Q+ Y A L+ G L ++D V NG A++RPPGHH++ + GFC FNNVAIAA YA Y+ + +ILIVDWDVHHG G Q+ F + +VLY S HRY++ F+P + S+VG GFN+N+ WNK + +S+Y++AF ++++P+++EF+P+LVIVSAGFD+A GDP G + PE F ++T +L LA GK+ + LEGGYNL + + V SLLG PT +I S +E+I+ Q YW K
Sbjct: 28 EVPERLTVSYEALRTHGLAQRCKAVPVRQATEQEILLAHSEEYLEAVKQTPGMNVEELMAFSKKYNDVYFHQNIYHCAKLAAGATLQLVDSVMKREVRNGMALVRPPGHHSQRSAANGFCVFNNVAIAALYAKKNYN--LNRILIVDWDVHHGQGIQYCFEEDPSVLYFSWHRYEHQSFWPNLPESDYSSVGKGKGSGFNINLPWNKVGMTNSDYLAAFFHVLLPVAYEFDPELVIVSAGFDSAIGDPEGEMCALPEIFAHLTHLLMPLAAGKMCVVLEGGYNLTSLGQSVCQTVHSLLGDPTPRISGLGTACDSALESIQNVRNVQSSYWSSFK 360
BLAST of Histone deacetylase,putative vs. Ensembl Zebrafish
Match: hdac4 (histone deacetylase 4 [Source:ZFIN;Acc:ZDB-GENE-061013-95]) HSP 1 Score: 301.212 bits (770), Expect = 2.207e-85 Identity = 161/378 (42.59%), Postives = 238/378 (62.96%), Query Frame = 2
Query: 1517 TCFVYDCRMENHM---NERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGN--ICQE-----SPTIYHL----FEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWN---KRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARG--DPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLG-----YPTNQIINFPINKSGIEAIRKTLEYQKPYWKCLK 2578
T VYD M+ H +IHPE R Q I+ L++ L +C+ + R A+ +E+ +HS +V G + Q+ +P L + ++I+ HS +A L+ G +++++ +V S NGFA++RPPGHHAE + P+GFC+FN+VAIAA L + ++ KILIVDWDVHHGNGTQ F+++ NVLY+SLHRYD+G FFPGS G+P VG GFNVN+A+ + P+ D++Y++AF ++VMPI++EF+PD+V+VS+GFDA G PLGG +T +CFG +T+ L LA G+++LALEGG++L I D CVS+LLG P + + P N + I+++ K LE Q YW+ L+
Sbjct: 599 TGLVYDTLMQKHQCMCGNSNIHPEHAGRIQSIWSRLQETGLRGQCECIRGRKATLEELQTVHSEAHVLLYGTNPLRQKLDSSVTPMFVRLPCGGIGVDSDTIWNEVHSSSAARLAVGSVVDLVFKVASGELRNGFAVVRPPGHHAEESTPMGFCYFNSVAIAAK--LLQQRLNVSKILIVDWDVHHGNGTQQAFYSDPNVLYLSLHRYDDGNFFPGS--GAPDEVGIGPGVGFNVNMAFTGGLEPPMGDADYLAAFRSVVMPIANEFSPDVVLVSSGFDAVEGHPPPLGGYKLTAKCFGYLTKQLMGLAGGRLVLALEGGHDLTAICDASEACVSALLGNELDPIPEDILQQRP-NANAIQSMEKVLEVQSKYWRSLQ 971 HSP 2 Score: 233.802 bits (595), Expect = 1.213e-62 Identity = 131/382 (34.29%), Postives = 214/382 (56.02%), Query Frame = 2
Query: 263 TAFVYDEQMLLHSNMW--DNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHV---------QLIEDTQTMTAIQLK--ELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLN---KTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPE--GSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDE------PCDSVKETIQNCLKFLHFFWKSLSVNVA 1336
T VYD M H M N++ E R++ + + ET L C I+ ++ E + HS++HV Q ++ + T ++L + D ++ + ++ A+ ++ GS ++++ V +NGF ++RPPGHHA ES GFC FN+V IAAK Q + KILIVDWDVHHGN TQ FY+ VLY+S+HRY+DGNF+P D +G G G+N+N+ + M ++DYL+ F S+++PIA E++P++VL+S+GFD+ G P G + CF ++T +LM LA GR+V+ LEGG+ + ++ D+ ++ L G +L+ E P + ++++ L+ +W+SL +V+
Sbjct: 599 TGLVYDTLMQKHQCMCGNSNIHPEHAGRIQSIWSRLQETGLRGQCECIRGRKATLEELQTVHSEAHVLLYGTNPLRQKLDSSVTPMFVRLPCGGIGVDSDTIWNEVHSSSAARLAVGSVVDLVFKVASGELRNGFAVVRPPGHHAEESTPMGFCYFNSVAIAAKLLQQRLNVSKILIVDWDVHHGNGTQQAFYSDPNVLYLSLHRYDDGNFFPG--SGAPDEVGIGPGVGFNVNMAFTGGLEPPMGDADYLAAFRSVVMPIANEFSPDVVLVSSGFDAVEGHPPPLGGYKLTAKCFGYLTKQLMGLAGGRLVLALEGGHDLTAICDASEACVSALLGN---ELDPIPEDILQQRPNANAIQSMEKVLEVQSKYWRSLQRSVS 975
BLAST of Histone deacetylase,putative vs. Ensembl Zebrafish
Match: hdac4 (histone deacetylase 4 [Source:ZFIN;Acc:ZDB-GENE-061013-95]) HSP 1 Score: 300.827 bits (769), Expect = 4.552e-85 Identity = 161/378 (42.59%), Postives = 238/378 (62.96%), Query Frame = 2
Query: 1517 TCFVYDCRMENHM---NERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGN--ICQE-----SPTIYHL----FEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWN---KRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARG--DPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLG-----YPTNQIINFPINKSGIEAIRKTLEYQKPYWKCLK 2578
T VYD M+ H +IHPE R Q I+ L++ L +C+ + R A+ +E+ +HS +V G + Q+ +P L + ++I+ HS +A L+ G +++++ +V S NGFA++RPPGHHAE + P+GFC+FN+VAIAA L + ++ KILIVDWDVHHGNGTQ F+++ NVLY+SLHRYD+G FFPGS G+P VG GFNVN+A+ + P+ D++Y++AF ++VMPI++EF+PD+V+VS+GFDA G PLGG +T +CFG +T+ L LA G+++LALEGG++L I D CVS+LLG P + + P N + I+++ K LE Q YW+ L+
Sbjct: 628 TGLVYDTLMQKHQCMCGNSNIHPEHAGRIQSIWSRLQETGLRGQCECIRGRKATLEELQTVHSEAHVLLYGTNPLRQKLDSSVTPMFVRLPCGGIGVDSDTIWNEVHSSSAARLAVGSVVDLVFKVASGELRNGFAVVRPPGHHAEESTPMGFCYFNSVAIAAK--LLQQRLNVSKILIVDWDVHHGNGTQQAFYSDPNVLYLSLHRYDDGNFFPGS--GAPDEVGIGPGVGFNVNMAFTGGLEPPMGDADYLAAFRSVVMPIANEFSPDVVLVSSGFDAVEGHPPPLGGYKLTAKCFGYLTKQLMGLAGGRLVLALEGGHDLTAICDASEACVSALLGNELDPIPEDILQQRP-NANAIQSMEKVLEVQSKYWRSLQ 1000 HSP 2 Score: 233.802 bits (595), Expect = 1.233e-62 Identity = 131/382 (34.29%), Postives = 214/382 (56.02%), Query Frame = 2
Query: 263 TAFVYDEQMLLHSNMW--DNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHV---------QLIEDTQTMTAIQLK--ELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLN---KTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPE--GSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDE------PCDSVKETIQNCLKFLHFFWKSLSVNVA 1336
T VYD M H M N++ E R++ + + ET L C I+ ++ E + HS++HV Q ++ + T ++L + D ++ + ++ A+ ++ GS ++++ V +NGF ++RPPGHHA ES GFC FN+V IAAK Q + KILIVDWDVHHGN TQ FY+ VLY+S+HRY+DGNF+P D +G G G+N+N+ + M ++DYL+ F S+++PIA E++P++VL+S+GFD+ G P G + CF ++T +LM LA GR+V+ LEGG+ + ++ D+ ++ L G +L+ E P + ++++ L+ +W+SL +V+
Sbjct: 628 TGLVYDTLMQKHQCMCGNSNIHPEHAGRIQSIWSRLQETGLRGQCECIRGRKATLEELQTVHSEAHVLLYGTNPLRQKLDSSVTPMFVRLPCGGIGVDSDTIWNEVHSSSAARLAVGSVVDLVFKVASGELRNGFAVVRPPGHHAEESTPMGFCYFNSVAIAAKLLQQRLNVSKILIVDWDVHHGNGTQQAFYSDPNVLYLSLHRYDDGNFFPG--SGAPDEVGIGPGVGFNVNMAFTGGLEPPMGDADYLAAFRSVVMPIANEFSPDVVLVSSGFDAVEGHPPPLGGYKLTAKCFGYLTKQLMGLAGGRLVLALEGGHDLTAICDASEACVSALLGN---ELDPIPEDILQQRPNANAIQSMEKVLEVQSKYWRSLQRSVS 1004
BLAST of Histone deacetylase,putative vs. Ensembl Xenopus
Match: gpr107 (G protein-coupled receptor 107 [Source:Xenbase;Acc:XB-GENE-953756]) HSP 1 Score: 602.823 bits (1553), Expect = 0.000e+0 Identity = 315/755 (41.72%), Postives = 431/755 (57.09%), Query Frame = 2
Query: 326 ERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKENDQLNHKIYELRTKNAFNNYP-NKTCFVYDCRMENHMNE-RSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINF-PINKSGIEAIRKTLEYQKPYWKCLKF 2581
E P R+ + + E L E C+ +Q +S S +V L+ TQ M +L+ LS ++D V+ + + ++ GS ++++ VL +NG ++RPPGHHA + +G+C+FN + IAA+YAQ Y +++LIVDWDVHHG TQ+ F N VLY S+HRYE+G FWP LRES +G G +N+N+ NKT M+++DY+ +F +I+LPIAYE+ P LVL++AGFDS +G P+G M P CF+H+TH LM LA+GR+++ LEGGY SL + V L L G PKL PC + + NC+ + + S + P+E K+ E P +T VYD +M H N S HPESP+R IF+ +D LL RC ++ SRLA++ E+ + HS +Y++ + P H E+NSIYIN SY SA L+ G +V ++NG I+RPPGHHAE GFCFFN VA+AA YA +I+I+DWDVHHGNGTQH F + +VLY+SLHRYD GLFFP S D S VG GFNVNI WN + D EY+ AF +VMPI++EFNP LV++SAGFDAARGDPLGG V+PE + +MT +L LA G+VIL LEGGYNL IS+ M C SLLG P + + P S ++RK + + YW+ L+
Sbjct: 45 ECPARIWAVRDKMAEYGLAERCVAVQVSP--RGWAGFSPSSRYVALMGSTQNMNVEELQALSDRYDSVYLHPTSFTCASLAVGSVLQLVDKVLRREIRNGLAVVRPPGHHAHVDQMNGYCMFNQLAIAARYAQRTYGAKRVLIVDWDVHHGQGTQFLFENDPSVLYFSVHRYENGGFWPHLRESASSAVGKERGERFNVNVAWNKTRMSDADYIHVFLNILLPIAYEFQPHLVLVAAGFDSVVGDPKGEMSATPGCFSHLTHLLMSLAQGRLILSLEGGYNQRSLAEGVCACLKALLGDPCPKLPLPSAPC---QRSALNCVT----------------------------AARASMSFLNGPPLE--------------KVLEQSMMEVMREVPAQRTALVYDEQMMEHHNMWDSCHPESPQRINQIFKRHKDLGLLDRCSRIPSRLATQKELQMCHSLSYIQKIEASAHMKPRDLHRLGNEYNSIYINSRSYHSARLAAGSTFSV--------AQNGVCIVRPPGHHAEPAEACGFCFFNTVALAARYA------QRLRIMILDWDVHHGNGTQHIFQEDASVLYVSLHRYDEGLFFPNSEDASHDKVGIGKGAGFNVNIPWNGSKMGDPEYLMAFHRVVMPIAYEFNPQLVLISAGFDAARGDPLGGCQVSPEGYAHMTHLLMGLAGGRVILVLEGGYNLTSISESMVMCTHSLLGDPPPTLSDLRPPKPSAFNSVRKVRQAHRKYWRSLRL 738 HSP 2 Score: 314.309 bits (804), Expect = 1.557e-90 Identity = 149/358 (41.62%), Postives = 228/358 (63.69%), Query Frame = 2
Query: 257 NKTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVN 1330
+TA VYDEQM+ H NMWD+ + E P R+ ++ + LL+ C RI ++ + + HS S++Q IE + M L L ++++ ++ ++ + ++ ++AGST V A+NG C++RPPGHHA +EA GFC FN V +AA+YAQ +I+I+DWDVHHGN TQ+ F + VLY+S+HRY++G F+P ++++D +G +G G+N+NIP N + M + +YL FH +++PIAYE+NP+LVLISAGFD+A G P G V P +AHMTH LM LA GRV+++LEGGY + S+ +S+V+ +L G PP L P S +++ + +W+SL +N
Sbjct: 394 QRTALVYDEQMMEHHNMWDSCHPESPQRINQIFKRHKDLGLLDRCSRIPSRLATQKELQMCHSLSYIQKIEASAHMKPRDLHRLGNEYNSIYINSRSYHSARLAAGSTFSV--------AQNGVCIVRPPGHHAEPAEACGFCFFNTVALAARYAQ----RLRIMILDWDVHHGNGTQHIFQEDASVLYVSLHRYDEGLFFPNSEDASHDKVGIGKGAGFNVNIPWNGSKMGDPEYLMAFHRVVMPIAYEFNPQLVLISAGFDAARGDPLGGCQVSPEGYAHMTHLLMGLAGGRVILVLEGGYNLTSISESMVMCTHSLLGDPPPTLSDLRPPKPSAFNSVRKVRQAHRKYWRSLRLN 739 HSP 3 Score: 264.233 bits (674), Expect = 4.676e-73 Identity = 131/331 (39.58%), Postives = 204/331 (61.63%), Query Frame = 2
Query: 1574 PESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQ--IINFPINKSG---IEAIRKTLEY 2551
PE P R + + + + L RC ++ ++ + G S YV +G+ + + ++S+Y++ S+ A L+ G +L ++D+V NG A++RPPGHHA V+ G+C FN +AIAA YA Y K++LIVDWDVHHG GTQ F + +VLY S+HRY+NG F+P + + SAVG + E FNVN+AWNK + D++YI F+NI++PI++EF P LV+V+AGFD+ GDP G ++ TP CF ++T +L SLA G++IL+LEGGYN +++ + C+ +LLG P + + + P +S + A R ++ +
Sbjct: 44 PECPARIWAVRDKMAEYGLAERCVAVQ--VSPRGWAGFSPSSRYVALMGSTQNMNVEELQALSDRYDSVYLHPTSFTCASLAVGSVLQLVDKVLRREIRNGLAVVRPPGHHAHVDQMNGYCMFNQLAIAARYAQRTYGA--KRVLIVDWDVHHGQGTQFLFENDPSVLYFSVHRYENGGFWPHLRESASSAVGKERGERFNVNVAWNKTRMSDADYIHVFLNILLPIAYEFQPHLVLVAAGFDSVVGDPKGEMSATPGCFSHLTHLLMSLAQGRLILSLEGGYNQRSLAEGVCACLKALLGDPCPKLPLPSAPCQRSALNCVTAARASMSF 370 HSP 4 Score: 109.768 bits (273), Expect = 1.224e-23 Identity = 49/90 (54.44%), Postives = 59/90 (65.56%), Query Frame = 2
Query: 3089 YAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQVFCGRFVQAHMMQHFQNTRHAIVLSFVDLSSWCYECDSYVHNE 3358
+AV PL WC HL V P A +DV C C S ENW+CLTCYQV CGR+V HM+ H + H +VLSF DLS WCY C+SYVH++
Sbjct: 823 FAVTPLPWCPHLGSVSAVPPAG-LDVRQLCAQCASELENWVCLTCYQVLCGRYVSQHMLCHGLASGHHLVLSFSDLSVWCYGCESYVHHQ 911
BLAST of Histone deacetylase,putative vs. Ensembl Xenopus
Match: ENSXETT00000022901.1 (histone deacetylase 10 [Source:NCBI gene;Acc:100497245]) HSP 1 Score: 353.984 bits (907), Expect = 3.475e-107 Identity = 164/365 (44.93%), Postives = 240/365 (65.75%), Query Frame = 2
Query: 263 TAFVYDEQMLLHSNMWDN--LYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHEP 1351
TA VYDE+M+ + +WD+ E P+RL Y+ + + +L++ C ++ +E +E I HS ++++++ TQTM +L+E+S ++ VFF N+ + +S G T++++ AVL +NG L+RPPGHH+ + +GFC+FNNV IAA+YA+ Y ++ILIVDWDVHHG QY F VLY S HRYE FWP L ES+Y+ +G +G G+NIN+P NK M+N+DY+++F ++LP+A+E+NPELVL+SAG+DSAIG PEG M P CF+H+T LM+LA G++ +LEGGY + SL +SV +T+ TL G PKL PC S E+IQN +WK L N+ H+P
Sbjct: 5 TALVYDEEMMSYKLLWDDQECSIEVPERLSSSYKRLQDYDLVKRCTQLPVREATDEEITLVHSSDYLEVVKSTQTMNEKELEEISRKYTAVFFHQNSFRCAKLSLGGTLQLVDAVLSGEVQNGMALVRPPGHHSQRDQGNGFCVFNNVAIAAEYAKKKYKLERILIVDWDVHHGQGIQYIFEEDPSVLYFSWHRYEHKTFWPYLSESDYNAVGRGKGTGFNINLPWNKVGMSNADYIAVFFHVLLPLAFEFNPELVLVSAGYDSAIGDPEGRMCATPECFSHLTSMLMNLADGKLCAVLEGGYNLRSLAESVCMTVRTLLGDPLPKLTGEMTPCHSALESIQNVRAAHSPYWKCLLCNLRSAHDP 369 HSP 2 Score: 288.886 bits (738), Expect = 1.225e-83 Identity = 144/357 (40.34%), Postives = 222/357 (62.18%), Query Frame = 2
Query: 1517 TCFVYDCRMENH---MNERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIIN-FPINKSGIEAIRKTLEYQKPYWKCL 2575
T VYD M ++ +++ E P R ++ L+D L+ RC QL R A+ +EI L+HS +Y+E + + + ++ +++ +Q+S+ A LS G L ++D V S +NG A++RPPGHH++ + GFC FNNVAIAA YA KY +++ILIVDWDVHHG G Q+ F + +VLY S HRY++ F+P ++ +AVG GFN+N+ WNK + +++YI+ F ++++P++ EFNP+LV+VSAG+D+A GDP G + TPECF ++T ML +LA+GK+ LEGGYNL +++ + V +LLG P ++ S +E+I+ PYWKCL
Sbjct: 5 TALVYDEEMMSYKLLWDDQECSIEVPERLSSSYKRLQDYDLVKRCTQLPVREATDEEITLVHSSDYLEVVKSTQTMNEKELEEISRKYTAVFFHQNSFRCAKLSLGGTLQLVDAVLSGEVQNGMALVRPPGHHSQRDQGNGFCVFNNVAIAAEYAKKKYK--LERILIVDWDVHHGQGIQYIFEEDPSVLYFSWHRYEHKTFWPYLSESDYNAVGRGKGTGFNINLPWNKVGMSNADYIAVFFHVLLPLAFEFNPELVLVSAGYDSAIGDPEGRMCATPECFSHLTSMLMNLADGKLCAVLEGGYNLRSLAESVCMTVRTLLGDPLPKLTGEMTPCHSALESIQNVRAAHSPYWKCL 359
BLAST of Histone deacetylase,putative vs. Ensembl Xenopus
Match: ENSXETT00000022890.1 (histone deacetylase 10 [Source:NCBI gene;Acc:100497245]) HSP 1 Score: 353.984 bits (907), Expect = 7.979e-107 Identity = 164/365 (44.93%), Postives = 240/365 (65.75%), Query Frame = 2
Query: 263 TAFVYDEQMLLHSNMWDN--LYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHEP 1351
TA VYDE+M+ + +WD+ E P+RL Y+ + + +L++ C ++ +E +E I HS ++++++ TQTM +L+E+S ++ VFF N+ + +S G T++++ AVL +NG L+RPPGHH+ + +GFC+FNNV IAA+YA+ Y ++ILIVDWDVHHG QY F VLY S HRYE FWP L ES+Y+ +G +G G+NIN+P NK M+N+DY+++F ++LP+A+E+NPELVL+SAG+DSAIG PEG M P CF+H+T LM+LA G++ +LEGGY + SL +SV +T+ TL G PKL PC S E+IQN +WK L N+ H+P
Sbjct: 5 TALVYDEEMMSYKLLWDDQECSIEVPERLSSSYKRLQDYDLVKRCTQLPVREATDEEITLVHSSDYLEVVKSTQTMNEKELEEISRKYTAVFFHQNSFRCAKLSLGGTLQLVDAVLSGEVQNGMALVRPPGHHSQRDQGNGFCVFNNVAIAAEYAKKKYKLERILIVDWDVHHGQGIQYIFEEDPSVLYFSWHRYEHKTFWPYLSESDYNAVGRGKGTGFNINLPWNKVGMSNADYIAVFFHVLLPLAFEFNPELVLVSAGYDSAIGDPEGRMCATPECFSHLTSMLMNLADGKLCAVLEGGYNLRSLAESVCMTVRTLLGDPLPKLTGEMTPCHSALESIQNVRAAHSPYWKCLLCNLRSAHDP 369 HSP 2 Score: 289.271 bits (739), Expect = 2.115e-83 Identity = 144/357 (40.34%), Postives = 222/357 (62.18%), Query Frame = 2
Query: 1517 TCFVYDCRMENH---MNERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIIN-FPINKSGIEAIRKTLEYQKPYWKCL 2575
T VYD M ++ +++ E P R ++ L+D L+ RC QL R A+ +EI L+HS +Y+E + + + ++ +++ +Q+S+ A LS G L ++D V S +NG A++RPPGHH++ + GFC FNNVAIAA YA KY +++ILIVDWDVHHG G Q+ F + +VLY S HRY++ F+P ++ +AVG GFN+N+ WNK + +++YI+ F ++++P++ EFNP+LV+VSAG+D+A GDP G + TPECF ++T ML +LA+GK+ LEGGYNL +++ + V +LLG P ++ S +E+I+ PYWKCL
Sbjct: 5 TALVYDEEMMSYKLLWDDQECSIEVPERLSSSYKRLQDYDLVKRCTQLPVREATDEEITLVHSSDYLEVVKSTQTMNEKELEEISRKYTAVFFHQNSFRCAKLSLGGTLQLVDAVLSGEVQNGMALVRPPGHHSQRDQGNGFCVFNNVAIAAEYAKKKYK--LERILIVDWDVHHGQGIQYIFEEDPSVLYFSWHRYEHKTFWPYLSESDYNAVGRGKGTGFNINLPWNKVGMSNADYIAVFFHVLLPLAFEFNPELVLVSAGYDSAIGDPEGRMCATPECFSHLTSMLMNLADGKLCAVLEGGYNLRSLAESVCMTVRTLLGDPLPKLTGEMTPCHSALESIQNVRAAHSPYWKCL 359
BLAST of Histone deacetylase,putative vs. Ensembl Xenopus
Match: ENSXETT00000036079.1 (histone deacetylase 10 [Source:NCBI gene;Acc:100497245]) HSP 1 Score: 348.977 bits (894), Expect = 1.525e-105 Identity = 164/367 (44.69%), Postives = 240/367 (65.40%), Query Frame = 2
Query: 263 TAFVYDEQMLLHSNMWDN--LYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSV--NVADNHEP 1351
TA VYDE+M+ + +WD+ E P+RL Y+ + + +L++ C ++ +E +E I HS ++++++ TQTM +L+E+S ++ VFF N+ + +S G T++++ AVL +NG L+RPPGHH+ + +GFC+FNNV IAA+YA+ Y ++ILIVDWDVHHG QY F VLY S HRYE FWP L ES+Y+ +G +G G+NIN+P NK M+N+DY+++F ++LP+A+E+NPELVL+SAG+DSAIG PEG M P CF+H+T LM+LA G++ +LEGGY + SL +SV +T+ TL G PKL PC S E+IQN +WK L N+ H+P
Sbjct: 5 TALVYDEEMMSYKLLWDDQECSIEVPERLSSSYKRLQDYDLVKRCTQLPVREATDEEITLVHSSDYLEVVKSTQTMNEKELEEISRKYTAVFFHQNSFRCAKLSLGGTLQLVDAVLSGEVQNGMALVRPPGHHSQRDQGNGFCVFNNVAIAAEYAKKKYKLERILIVDWDVHHGQGIQYIFEEDPSVLYFSWHRYEHKTFWPYLSESDYNAVGRGKGTGFNINLPWNKVGMSNADYIAVFFHVLLPLAFEFNPELVLVSAGYDSAIGDPEGRMCATPECFSHLTSMLMNLADGKLCAVLEGGYNLRSLAESVCMTVRTLLGDPLPKLTGEMTPCHSALESIQNVRAAHSPYWKCLLCDGNLRSAHDP 371 HSP 2 Score: 289.656 bits (740), Expect = 6.446e-84 Identity = 144/357 (40.34%), Postives = 222/357 (62.18%), Query Frame = 2
Query: 1517 TCFVYDCRMENH---MNERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIIN-FPINKSGIEAIRKTLEYQKPYWKCL 2575
T VYD M ++ +++ E P R ++ L+D L+ RC QL R A+ +EI L+HS +Y+E + + + ++ +++ +Q+S+ A LS G L ++D V S +NG A++RPPGHH++ + GFC FNNVAIAA YA KY +++ILIVDWDVHHG G Q+ F + +VLY S HRY++ F+P ++ +AVG GFN+N+ WNK + +++YI+ F ++++P++ EFNP+LV+VSAG+D+A GDP G + TPECF ++T ML +LA+GK+ LEGGYNL +++ + V +LLG P ++ S +E+I+ PYWKCL
Sbjct: 5 TALVYDEEMMSYKLLWDDQECSIEVPERLSSSYKRLQDYDLVKRCTQLPVREATDEEITLVHSSDYLEVVKSTQTMNEKELEEISRKYTAVFFHQNSFRCAKLSLGGTLQLVDAVLSGEVQNGMALVRPPGHHSQRDQGNGFCVFNNVAIAAEYAKKKYK--LERILIVDWDVHHGQGIQYIFEEDPSVLYFSWHRYEHKTFWPYLSESDYNAVGRGKGTGFNINLPWNKVGMSNADYIAVFFHVLLPLAFEFNPELVLVSAGYDSAIGDPEGRMCATPECFSHLTSMLMNLADGKLCAVLEGGYNLRSLAESVCMTVRTLLGDPLPKLTGEMTPCHSALESIQNVRAAHSPYWKCL 359
BLAST of Histone deacetylase,putative vs. Ensembl Xenopus
Match: ENSXETT00000022845.1 (histone deacetylase 10 [Source:NCBI gene;Acc:100497245]) HSP 1 Score: 333.569 bits (854), Expect = 1.369e-101 Identity = 157/353 (44.48%), Postives = 230/353 (65.16%), Query Frame = 2
Query: 305 MWDN--LYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSV--NVADNHEP 1351
+WD+ E P+RL Y+ + + +L++ C ++ +E +E I HS ++++++ TQTM +L+E+S ++ VFF N+ + +S G T++++ AVL +NG L+RPPGHH+ + +GFC+FNNV IAA+YA+ Y ++ILIVDWDVHHG QY F VLY S HRYE FWP L ES+Y+ +G +G G+NIN+P NK M+N+DY+++F ++LP+A+E+NPELVL+SAG+DSAIG PEG M P CF+H+T LM+LA G++ +LEGGY + SL +SV +T+ TL G PKL PC S E+IQN +WK L N+ H+P
Sbjct: 6 LWDDQECSIEVPERLSSSYKRLQDYDLVKRCTQLPVREATDEEITLVHSSDYLEVVKSTQTMNEKELEEISRKYTAVFFHQNSFRCAKLSLGGTLQLVDAVLSGEVQNGMALVRPPGHHSQRDQGNGFCVFNNVAIAAEYAKKKYKLERILIVDWDVHHGQGIQYIFEEDPSVLYFSWHRYEHKTFWPYLSESDYNAVGRGKGTGFNINLPWNKVGMSNADYIAVFFHVLLPLAFEFNPELVLVSAGYDSAIGDPEGRMCATPECFSHLTSMLMNLADGKLCAVLEGGYNLRSLAESVCMTVRTLLGDPLPKLTGEMTPCHSALESIQNVRAAHSPYWKCLLCDGNLRSAHDP 358 HSP 2 Score: 285.419 bits (729), Expect = 4.584e-84 Identity = 139/334 (41.62%), Postives = 212/334 (63.47%), Query Frame = 2
Query: 1577 ESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIIN-FPINKSGIEAIRKTLEYQKPYWKCL 2575
E P R ++ L+D L+ RC QL R A+ +EI L+HS +Y+E + + + ++ +++ +Q+S+ A LS G L ++D V S +NG A++RPPGHH++ + GFC FNNVAIAA YA KY +++ILIVDWDVHHG G Q+ F + +VLY S HRY++ F+P ++ +AVG GFN+N+ WNK + +++YI+ F ++++P++ EFNP+LV+VSAG+D+A GDP G + TPECF ++T ML +LA+GK+ LEGGYNL +++ + V +LLG P ++ S +E+I+ PYWKCL
Sbjct: 15 EVPERLSSSYKRLQDYDLVKRCTQLPVREATDEEITLVHSSDYLEVVKSTQTMNEKELEEISRKYTAVFFHQNSFRCAKLSLGGTLQLVDAVLSGEVQNGMALVRPPGHHSQRDQGNGFCVFNNVAIAAEYAKKKYK--LERILIVDWDVHHGQGIQYIFEEDPSVLYFSWHRYEHKTFWPYLSESDYNAVGRGKGTGFNINLPWNKVGMSNADYIAVFFHVLLPLAFEFNPELVLVSAGYDSAIGDPEGRMCATPECFSHLTSMLMNLADGKLCAVLEGGYNLRSLAESVCMTVRTLLGDPLPKLTGEMTPCHSALESIQNVRAAHSPYWKCL 346
BLAST of Histone deacetylase,putative vs. Ensembl Mouse
Match: Hdac6 (histone deacetylase 6 [Source:MGI Symbol;Acc:MGI:1333752]) HSP 1 Score: 716.457 bits (1848), Expect = 0.000e+0 Identity = 413/1115 (37.04%), Postives = 595/1115 (53.36%), Query Frame = 2
Query: 218 GLYDNIELRINFPNKTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKENDQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMN-ERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINF-PINKSGIEAIRKTLEYQKPYWKCLKFYE----------PLVVTYTEISPNQTNPAALDNIVQIDTNTLAESVRQLGIVEVTFQTEQSIEETLSQPRN---DTFITEPNSSNPIIHLPPI-VSSDNAVEVPATTSINSTTHATQNISANFLSVD----------------QSSGATPVSA---------------NVSRVINEGNSV--GLVLQDIMNLSGVSNSDIHHFLGLTSNDPLPERVYAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQVFCGRFVQAHMMQHFQNTRHAIVLSFVDLSSWCYECDSYVHNECLNHAKREAHIAKFGVPQP 3415
GL N E R+ P T V+DEQ+ +WD+ + E P+RL E + LL C+ QA+ + E + HS ++ L+E TQ M +L+ L+ +D V+ N+ + ++ GS + ++ A++ +NG +IRPPGHHA + G+C+FN++ +AA+YAQ + Q++LIVDWDVHHG TQ+ F VLY SIHRYE G FWP L+ SN+ IG +G+GY IN+P N+T M ++DY++ F I+LP+A E+ P+LVL++AGFD+ G P+G M PA FAH+TH LM LA G++++ LEGGY + +L V +L TL G P LE PC S + +I L+ L FW+ L +V E E E + LP++ P N+T VYD +M +H N + HPE+P+R I L + L +RC L +R A E+ HS YVE L + H F+SIYI ++ A L+ G +++ V S NG A++RPPGHHAE N GFCFFN+VA+AA +A ++ +ILIVDWDVHHGNGTQH F + +VLY+SLHRYD G FFP +G+ S VG D GF VN+ WN + D++Y++A+ +V+PI++EFNP+LV++SAGFDAA+GDPLGG VTPE + ++T +L LA G++IL LEGGYNL IS+ M+ C SLLG P Q+ P + +I + ++ + YW+ L+ + LV+ P +P + + ESVR+ T E TL Q ++ + + SS + +++ ATT + ++ A +N SV+ Q++GA+P+ +SR E + GL+ + S F + D YAV PL WC HL V P+A +DV+ C C + +ENW+CLTCYQV+C R+V AHM+ H + + H +VLS VDLS+WCY C +YVH+E L K AH KFG P
Sbjct: 72 GLDLNPETRV--PVGTGLVFDEQLNDFHCLWDDSFPESPERLHAIREQLILEGLLGRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLAETYDSVYLHPNSYSCACLATGSVLRLVDALMGAEIRNGMAVIRPPGHHAQHNLMDGYCMFNHLAVAARYAQKKHRIQRVLIVDWDVHHGQGTQFIFDQDPSVLYFSIHRYEHGRFWPHLKASNWSTIGFGQGQGYTINVPWNQTGMRDADYIAAFLHILLPVASEFQPQLVLVAAGFDALHGDPKGEMAATPAGFAHLTHLLMGLAGGKLILSLEGGYNLRALAKGVSASLHTLLGDPCPMLESCVVPCASAQTSIYCTLEALEPFWEVLERSVETQEEDEVEEAVLEEEEEEGGWEATALPMDTWP-----------------------LLQNRTGLVYDEKMMSHCNLWDNHHPETPQRILRIMCHLEEVGLAARCLILPARPALDSELLTCHSAEYVEHLRTTEKMKTRDLHREGANFDSIYICPSTFACAKLATGAACRLVEAVLSGEVLNGIAVVRPPGHHAEPNAACGFCFFNSVAVAARHAQIIAGRAL-RILIVDWDVHHGNGTQHIFEDDPSVLYVSLHRYDRGTFFPMGDEGASSQVGRDAGIGFTVNVPWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLISAGFDAAQGDPLGGCQVTPEGYAHLTHLLMGLAGGRIILILEGGYNLASISESMAACTHSLLGDPPPQLTLLRPPQSGALVSISEVIQVHRKYWRSLRLMKMEDKEECSSSRLVIKKL---PPTASPVSAKEMTTPKGKVPEESVRK------TIAALPGKESTLGQAKSKMAKAVLAQGQSSEQAAKGTTLDLATSKETVGGATTDLWASAAAPENFPNQTTSVEALGETEPTPPASHTNKQTTGASPLQGVTAQQSLQLGVLSTLELSREAEEAHDSEEGLLGEAAGGQDMNSLMLTQGFGDFNTQDVF----YAVTPLSWCPHLMAVCPIPAAG-LDVSQPCKTCGTVQENWVCLTCYQVYCSRYVNAHMVCHHEASEHPLVLSCVDLSTWCYVCQAYVHHEDLQDVKNAAHQNKFGEDMP 1146
BLAST of Histone deacetylase,putative vs. Ensembl Mouse
Match: Hdac6 (histone deacetylase 6 [Source:MGI Symbol;Acc:MGI:1333752]) HSP 1 Score: 716.457 bits (1848), Expect = 0.000e+0 Identity = 413/1115 (37.04%), Postives = 595/1115 (53.36%), Query Frame = 2
Query: 218 GLYDNIELRINFPNKTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKENDQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMN-ERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINF-PINKSGIEAIRKTLEYQKPYWKCLKFYE----------PLVVTYTEISPNQTNPAALDNIVQIDTNTLAESVRQLGIVEVTFQTEQSIEETLSQPRN---DTFITEPNSSNPIIHLPPI-VSSDNAVEVPATTSINSTTHATQNISANFLSVD----------------QSSGATPVSA---------------NVSRVINEGNSV--GLVLQDIMNLSGVSNSDIHHFLGLTSNDPLPERVYAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQVFCGRFVQAHMMQHFQNTRHAIVLSFVDLSSWCYECDSYVHNECLNHAKREAHIAKFGVPQP 3415
GL N E R+ P T V+DEQ+ +WD+ + E P+RL E + LL C+ QA+ + E + HS ++ L+E TQ M +L+ L+ +D V+ N+ + ++ GS + ++ A++ +NG +IRPPGHHA + G+C+FN++ +AA+YAQ + Q++LIVDWDVHHG TQ+ F VLY SIHRYE G FWP L+ SN+ IG +G+GY IN+P N+T M ++DY++ F I+LP+A E+ P+LVL++AGFD+ G P+G M PA FAH+TH LM LA G++++ LEGGY + +L V +L TL G P LE PC S + +I L+ L FW+ L +V E E E + LP++ P N+T VYD +M +H N + HPE+P+R I L + L +RC L +R A E+ HS YVE L + H F+SIYI ++ A L+ G +++ V S NG A++RPPGHHAE N GFCFFN+VA+AA +A ++ +ILIVDWDVHHGNGTQH F + +VLY+SLHRYD G FFP +G+ S VG D GF VN+ WN + D++Y++A+ +V+PI++EFNP+LV++SAGFDAA+GDPLGG VTPE + ++T +L LA G++IL LEGGYNL IS+ M+ C SLLG P Q+ P + +I + ++ + YW+ L+ + LV+ P +P + + ESVR+ T E TL Q ++ + + SS + +++ ATT + ++ A +N SV+ Q++GA+P+ +SR E + GL+ + S F + D YAV PL WC HL V P+A +DV+ C C + +ENW+CLTCYQV+C R+V AHM+ H + + H +VLS VDLS+WCY C +YVH+E L K AH KFG P
Sbjct: 72 GLDLNPETRV--PVGTGLVFDEQLNDFHCLWDDSFPESPERLHAIREQLILEGLLGRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLAETYDSVYLHPNSYSCACLATGSVLRLVDALMGAEIRNGMAVIRPPGHHAQHNLMDGYCMFNHLAVAARYAQKKHRIQRVLIVDWDVHHGQGTQFIFDQDPSVLYFSIHRYEHGRFWPHLKASNWSTIGFGQGQGYTINVPWNQTGMRDADYIAAFLHILLPVASEFQPQLVLVAAGFDALHGDPKGEMAATPAGFAHLTHLLMGLAGGKLILSLEGGYNLRALAKGVSASLHTLLGDPCPMLESCVVPCASAQTSIYCTLEALEPFWEVLERSVETQEEDEVEEAVLEEEEEEGGWEATALPMDTWP-----------------------LLQNRTGLVYDEKMMSHCNLWDNHHPETPQRILRIMCHLEEVGLAARCLILPARPALDSELLTCHSAEYVEHLRTTEKMKTRDLHREGANFDSIYICPSTFACAKLATGAACRLVEAVLSGEVLNGIAVVRPPGHHAEPNAACGFCFFNSVAVAARHAQIIAGRAL-RILIVDWDVHHGNGTQHIFEDDPSVLYVSLHRYDRGTFFPMGDEGASSQVGRDAGIGFTVNVPWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLISAGFDAAQGDPLGGCQVTPEGYAHLTHLLMGLAGGRIILILEGGYNLASISESMAACTHSLLGDPPPQLTLLRPPQSGALVSISEVIQVHRKYWRSLRLMKMEDKEECSSSRLVIKKL---PPTASPVSAKEMTTPKGKVPEESVRK------TIAALPGKESTLGQAKSKMAKAVLAQGQSSEQAAKGTTLDLATSKETVGGATTDLWASAAAPENFPNQTTSVEALGETEPTPPASHTNKQTTGASPLQGVTAQQSLQLGVLSTLELSREAEEAHDSEEGLLGEAAGGQDMNSLMLTQGFGDFNTQDVF----YAVTPLSWCPHLMAVCPIPAAG-LDVSQPCKTCGTVQENWVCLTCYQVYCSRYVNAHMVCHHEASEHPLVLSCVDLSTWCYVCQAYVHHEDLQDVKNAAHQNKFGEDMP 1146
BLAST of Histone deacetylase,putative vs. Ensembl Mouse
Match: Hdac6 (histone deacetylase 6 [Source:MGI Symbol;Acc:MGI:1333752]) HSP 1 Score: 619.002 bits (1595), Expect = 0.000e+0 Identity = 322/793 (40.61%), Postives = 462/793 (58.26%), Query Frame = 2
Query: 215 HGLYDNIELRINFPNKTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKENDQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMN-ERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINF-PINKSGIEAIRKTLEYQKPYWKCLKFYE 2587
GL N E R+ P T V+DEQ+ +WD+ + E P+RL E + LL C+ QA+ + E + HS ++ L+E TQ M +L+ L+ +D V+ N+ + ++ GS + ++ A++ +NG +IRPPGHHA + G+C+FN++ +AA+YAQ + Q++LIVDWDVHHG TQ+ F VLY SIHRYE G FWP L+ SN+ IG +G+GY IN+P N+T M ++DY++ F I+LP+A E+ P+LVL++AGFD+ G P+G M PA FAH+TH LM LA G++++ LEGGY + +L V +L TL G P LE PC S + +I L+ L FW+ L +V E E E + LP++ P N+T VYD +M +H N + HPE+P+R I L + L +RC L +R A E+ HS YVE L + H F+SIYI ++ A L+ G +++ V S NG A++RPPGHHAE N GFCFFN+VA+AA +A ++ +ILIVDWDVHHGNGTQH F + +VLY+SLHRYD G FFP +G+ S VG D GF VN+ WN + D++Y++A+ +V+PI++EFNP+LV++SAGFDAA+GDPLGG VTPE + ++T +L LA G++IL LEGGYNL IS+ M+ C SLLG P Q+ P + +I + ++ + YW+ L+ +
Sbjct: 71 QGLDLNPETRV--PVGTGLVFDEQLNDFHCLWDDSFPESPERLHAIREQLILEGLLGRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLAETYDSVYLHPNSYSCACLATGSVLRLVDALMGAEIRNGMAVIRPPGHHAQHNLMDGYCMFNHLAVAARYAQKKHRIQRVLIVDWDVHHGQGTQFIFDQDPSVLYFSIHRYEHGRFWPHLKASNWSTIGFGQGQGYTINVPWNQTGMRDADYIAAFLHILLPVASEFQPQLVLVAAGFDALHGDPKGEMAATPAGFAHLTHLLMGLAGGKLILSLEGGYNLRALAKGVSASLHTLLGDPCPMLESCVVPCASAQTSIYCTLEALEPFWEVLERSVETQEEDEVEEAVLEEEEEEGGWEATALPMDTWP-----------------------LLQNRTGLVYDEKMMSHCNLWDNHHPETPQRILRIMCHLEEVGLAARCLILPARPALDSELLTCHSAEYVEHLRTTEKMKTRDLHREGANFDSIYICPSTFACAKLATGAACRLVEAVLSGEVLNGIAVVRPPGHHAEPNAACGFCFFNSVAVAARHAQIIAGRAL-RILIVDWDVHHGNGTQHIFEDDPSVLYVSLHRYDRGTFFPMGDEGASSQVGRDAGIGFTVNVPWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLISAGFDAAQGDPLGGCQVTPEGYAHLTHLLMGLAGGRIILILEGGYNLASISESMAACTHSLLGDPPPQLTLLRPPQSGALVSISEVIQVHRKYWRSLRLMK 837 HSP 2 Score: 299.671 bits (766), Expect = 5.879e-85 Identity = 154/422 (36.49%), Postives = 236/422 (55.92%), Query Frame = 2
Query: 257 NKTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAK-EIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQ-KILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKENDQLNHKIYELRTKNAFNNYPNK 1516
N+T VYDE+M+ H N+WDN + E P R+ + E L C+ + A+ +D+EL+ HS +V+ + T+ M L + D ++ +T + ++ G+ +++AVL NG ++RPPGHHA + A GFC FN+V +AA++AQ+ +ILIVDWDVHHGN TQ+ F + VLY+S+HRY+ G F+P E +G + G G+ +N+P N M ++DYL+ +H ++LPIAYE+NPELVLISAGFD+A G P G V P +AH+TH LM LA GR++++LEGGY + S+ +S+ +L G PP+L P +I ++ +W+SL + ++ E E + + + KLP +P KE K+ E + P K
Sbjct: 478 NRTGLVYDEKMMSHCNLWDNHHPETPQRILRIMCHLEEVGLAARCLILPARPALDSELLT-CHSAEYVEHLRTTEKMKTRDLHREGANFDSIYICPSTFACAKLATGAACRLVEAVLSGEVLNGIAVVRPPGHHAEPNAACGFCFFNSVAVAARHAQIIAGRALRILIVDWDVHHGNGTQHIFEDDPSVLYVSLHRYDRGTFFPMGDEGASSQVGRDAGIGFTVNVPWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLISAGFDAAQGDPLGGCQVTPEGYAHLTHLLMGLAGGRIILILEGGYNLASISESMAACTHSLLGDPPPQLTLLRPPQSGALVSISEVIQVHRKYWRSLRLMKMEDKE----------ECSSSRLVIKKLPPTASPVSAKEMTTPKGKVPEESVRKTIAALPGK 888
BLAST of Histone deacetylase,putative vs. Ensembl Mouse
Match: Hdac10 (histone deacetylase 10 [Source:MGI Symbol;Acc:MGI:2158340]) HSP 1 Score: 341.658 bits (875), Expect = 5.962e-103 Identity = 169/381 (44.36%), Postives = 233/381 (61.15%), Query Frame = 2
Query: 263 TAFVYDEQMLLHSNMWDN--LYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVA-----DNHEPYPEYLRHLPES 1384
TA VY E M +WD+ E P+RL +G+ + L E C+ + A E E + HS ++ L++ TQT+ +L LS Q++ V+F +T + ++AG+ ++++ AVL NG L+RPPGHH+ + A+GFC+FNNV +AAK+A+ Y Q+ILIVDWDVHHG QY F + VLY S HRYE G+FWP L ES+ D +G +G+G+ +N+P N+ M N+DYL+ F ++LP+A+E++PELVL+SAGFDSAIG PEG M P CFAH+T L LA GR+ +LEGGY +ESL SV + + TL G P L PC S E+IQ+ +W SL NVA H P LR L ES
Sbjct: 3 TALVYHEDMTATRLLWDDPECEIECPERLTAALDGLRQRGLEERCLCLSACEASEEELGLVHSPEYIALVQKTQTLDKEELHALSKQYNAVYFHPDTFHCARLAAGAALQLVDAVLTGAVHNGLALVRPPGHHSQRAAANGFCVFNNVALAAKHAKQKYGLQRILIVDWDVHHGQGIQYIFNDDPSVLYFSWHRYEHGSFWPFLPESDADAVGQGQGQGFTVNLPWNQVGMGNADYLAAFLHVLLPLAFEFDPELVLVSAGFDSAIGDPEGQMQATPECFAHLTQLLQVLAGGRICAVLEGGYHLESLAQSVCMMVQTLLGDPTPPLLGLMVPCQSALESIQSVQTAQTPYWTSLQQNVAPVLSSSTHSPEERSLRLLGES 383 HSP 2 Score: 283.493 bits (724), Expect = 5.103e-82 Identity = 138/357 (38.66%), Postives = 221/357 (61.90%), Query Frame = 2
Query: 1577 ESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTI----YHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINFPIN-KSGIEAIRKTLEYQKPYWKCLKFYEPLVVTYTEISPNQTN 2632
E P R + LR L RC L + AS++E+GL+HSP Y+ + Q++ T+ H +++N++Y + ++ A L+ G L ++D V + NG A++RPPGHH++ GFC FNNVA+AA +A KY +++ILIVDWDVHHG G Q+ F + +VLY S HRY++G F+P + AVG +GF VN+ WN+ + +++Y++AF+++++P++ EF+P+LV+VSAGFD+A GDP G + TPECF ++TQ+L LA G++ LEGGY+L ++ + V +LLG PT ++ + +S +E+I+ Q PYW L+ V++ + SP + +
Sbjct: 26 ECPERLTAALDGLRQRGLEERCLCLSACEASEEELGLVHSPEYI----ALVQKTQTLDKEELHALSKQYNAVYFHPDTFHCARLAAGAALQLVDAVLTGAVHNGLALVRPPGHHSQRAAANGFCVFNNVALAAKHAKQKYG--LQRILIVDWDVHHGQGIQYIFNDDPSVLYFSWHRYEHGSFWPFLPESDADAVGQGQGQGFTVNLPWNQVGMGNADYLAAFLHVLLPLAFEFDPELVLVSAGFDSAIGDPEGQMQATPECFAHLTQLLQVLAGGRICAVLEGGYHLESLAQSVCMMVQTLLGDPTPPLLGLMVPCQSALESIQSVQTAQTPYWTSLQQNVAPVLSSSTHSPEERS 376
BLAST of Histone deacetylase,putative vs. Ensembl Mouse
Match: Hdac9 (histone deacetylase 9 [Source:MGI Symbol;Acc:MGI:1931221]) HSP 1 Score: 300.827 bits (769), Expect = 3.534e-85 Identity = 160/385 (41.56%), Postives = 231/385 (60.00%), Query Frame = 2
Query: 1517 TCFVYDCRMENHM---NERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNY-----VESLGNICQESPTIYHLFEEEF-------------NSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKR---PVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARG--DPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQI----INFPINKSGIEAIRKTLEYQKPYWKCLKF 2581
T YD M H + HPE R Q I+ L++ LLS+C++++ R AS +EI L+HS ++ L + T+ +F ++I+ HS +A ++ G ++ + +V S +NGFA++RPPGHHAE + +GFCFFN+VAI A Y + + I KILIVD DVHHGNGTQ F+ + ++LYISLHRYD G FFPGS G+P+ VG EG+NVNIAW P+ D EY+ AF +VMP++ EF+PD+V+VSAGFDA G PLGG VT +CFG++T+ L +LANG+V LALEGG++L I D C+++LLG + ++ +N + +++KT++ Q YWK +K
Sbjct: 590 TGIAYDPLMLKHQCICGSSTTHPEHAGRIQSIWSRLQETGLLSKCERIQGRKASLEEIQLVHSEHHSLLYGTSPLDGQKLDPRTLLGDDSRKFFSSLPCGGLGVDSDTIWNELHSSGAARMAVGCVIELASKVASGELKNGFAVVRPPGHHAEESAAMGFCFFNSVAITAKYLRDQLN--ISKILIVDLDVHHGNGTQQAFYADPSILYISLHRYDEGNFFPGS--GAPNEVGVGLGEGYNVNIAWTGGLDPPMGDVEYLEAFRTVVMPVAREFDPDMVLVSAGFDALEGHTPPLGGYKVTAKCFGHLTKQLMTLANGRVALALEGGHDLTAICDASEACINALLGNEPGPLEEDALHQSVNTNAAASLQKTIDIQSKYWKSIKM 970 HSP 2 Score: 233.032 bits (593), Expect = 2.353e-62 Identity = 138/387 (35.66%), Postives = 203/387 (52.45%), Query Frame = 2
Query: 263 TAFVYDEQMLLHSNMWDN--LYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIE---------DTQTM---------TAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLN---KTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIG--CPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSV----KETIQNCLKFLHFFWKSLSVNVA 1336
T YD ML H + + + E R++ + + ET LL C RIQ ++ E I HS+ H L D +T+ +++ L D ++ + ++ A+ ++ G IE+ V KNGF ++RPPGHHA ES A GFC FN+V I AKY + + KILIVD DVHHGN TQ FY +LYIS+HRY++GNF+P N +G G GYN+NI M + +YL F ++++P+A E++P++VL+SAGFD+ G P G V CF H+T +LM LA GRV + LEGG+ + ++ D+ + L G P LE+ D SV ++Q + +WKS+ + A
Sbjct: 590 TGIAYDPLMLKHQCICGSSTTHPEHAGRIQSIWSRLQETGLLSKCERIQGRKASLEEIQLVHSEHHSLLYGTSPLDGQKLDPRTLLGDDSRKFFSSLPCGGLGVDSDTIWNELHSSGAARMAVGCVIELASKVASGELKNGFAVVRPPGHHAEESAAMGFCFFNSVAITAKYLRDQLNISKILIVDLDVHHGNGTQQAFYADPSILYISLHRYDEGNFFPGSGAPN--EVGVGLGEGYNVNIAWTGGLDPPMGDVEYLEAFRTVVMPVAREFDPDMVLVSAGFDALEGHTPPLGGYKVTAKCFGHLTKQLMTLANGRVALALEGGHDLTAICDASEACINALLGNEPGPLEE-DALHQSVNTNAAASLQKTIDIQSKYWKSIKMVAA 973
BLAST of Histone deacetylase,putative vs. UniProt/SwissProt
Match: sp|Q9Z2V5|HDAC6_MOUSE (Histone deacetylase 6 OS=Mus musculus OX=10090 GN=Hdac6 PE=1 SV=3) HSP 1 Score: 716.457 bits (1848), Expect = 0.000e+0 Identity = 413/1115 (37.04%), Postives = 595/1115 (53.36%), Query Frame = 2
Query: 218 GLYDNIELRINFPNKTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKENDQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMN-ERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINF-PINKSGIEAIRKTLEYQKPYWKCLKFYE----------PLVVTYTEISPNQTNPAALDNIVQIDTNTLAESVRQLGIVEVTFQTEQSIEETLSQPRN---DTFITEPNSSNPIIHLPPI-VSSDNAVEVPATTSINSTTHATQNISANFLSVD----------------QSSGATPVSA---------------NVSRVINEGNSV--GLVLQDIMNLSGVSNSDIHHFLGLTSNDPLPERVYAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQVFCGRFVQAHMMQHFQNTRHAIVLSFVDLSSWCYECDSYVHNECLNHAKREAHIAKFGVPQP 3415
GL N E R+ P T V+DEQ+ +WD+ + E P+RL E + LL C+ QA+ + E + HS ++ L+E TQ M +L+ L+ +D V+ N+ + ++ GS + ++ A++ +NG +IRPPGHHA + G+C+FN++ +AA+YAQ + Q++LIVDWDVHHG TQ+ F VLY SIHRYE G FWP L+ SN+ IG +G+GY IN+P N+T M ++DY++ F I+LP+A E+ P+LVL++AGFD+ G P+G M PA FAH+TH LM LA G++++ LEGGY + +L V +L TL G P LE PC S + +I L+ L FW+ L +V E E E + LP++ P N+T VYD +M +H N + HPE+P+R I L + L +RC L +R A E+ HS YVE L + H F+SIYI ++ A L+ G +++ V S NG A++RPPGHHAE N GFCFFN+VA+AA +A ++ +ILIVDWDVHHGNGTQH F + +VLY+SLHRYD G FFP +G+ S VG D GF VN+ WN + D++Y++A+ +V+PI++EFNP+LV++SAGFDAA+GDPLGG VTPE + ++T +L LA G++IL LEGGYNL IS+ M+ C SLLG P Q+ P + +I + ++ + YW+ L+ + LV+ P +P + + ESVR+ T E TL Q ++ + + SS + +++ ATT + ++ A +N SV+ Q++GA+P+ +SR E + GL+ + S F + D YAV PL WC HL V P+A +DV+ C C + +ENW+CLTCYQV+C R+V AHM+ H + + H +VLS VDLS+WCY C +YVH+E L K AH KFG P
Sbjct: 72 GLDLNPETRV--PVGTGLVFDEQLNDFHCLWDDSFPESPERLHAIREQLILEGLLGRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLAETYDSVYLHPNSYSCACLATGSVLRLVDALMGAEIRNGMAVIRPPGHHAQHNLMDGYCMFNHLAVAARYAQKKHRIQRVLIVDWDVHHGQGTQFIFDQDPSVLYFSIHRYEHGRFWPHLKASNWSTIGFGQGQGYTINVPWNQTGMRDADYIAAFLHILLPVASEFQPQLVLVAAGFDALHGDPKGEMAATPAGFAHLTHLLMGLAGGKLILSLEGGYNLRALAKGVSASLHTLLGDPCPMLESCVVPCASAQTSIYCTLEALEPFWEVLERSVETQEEDEVEEAVLEEEEEEGGWEATALPMDTWP-----------------------LLQNRTGLVYDEKMMSHCNLWDNHHPETPQRILRIMCHLEEVGLAARCLILPARPALDSELLTCHSAEYVEHLRTTEKMKTRDLHREGANFDSIYICPSTFACAKLATGAACRLVEAVLSGEVLNGIAVVRPPGHHAEPNAACGFCFFNSVAVAARHAQIIAGRAL-RILIVDWDVHHGNGTQHIFEDDPSVLYVSLHRYDRGTFFPMGDEGASSQVGRDAGIGFTVNVPWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLISAGFDAAQGDPLGGCQVTPEGYAHLTHLLMGLAGGRIILILEGGYNLASISESMAACTHSLLGDPPPQLTLLRPPQSGALVSISEVIQVHRKYWRSLRLMKMEDKEECSSSRLVIKKL---PPTASPVSAKEMTTPKGKVPEESVRK------TIAALPGKESTLGQAKSKMAKAVLAQGQSSEQAAKGTTLDLATSKETVGGATTDLWASAAAPENFPNQTTSVEALGETEPTPPASHTNKQTTGASPLQGVTAQQSLQLGVLSTLELSREAEEAHDSEEGLLGEAAGGQDMNSLMLTQGFGDFNTQDVF----YAVTPLSWCPHLMAVCPIPAAG-LDVSQPCKTCGTVQENWVCLTCYQVYCSRYVNAHMVCHHEASEHPLVLSCVDLSTWCYVCQAYVHHEDLQDVKNAAHQNKFGEDMP 1146
BLAST of Histone deacetylase,putative vs. UniProt/SwissProt
Match: sp|Q9UBN7|HDAC6_HUMAN (Histone deacetylase 6 OS=Homo sapiens OX=9606 GN=HDAC6 PE=1 SV=2) HSP 1 Score: 602.438 bits (1552), Expect = 0.000e+0 Identity = 315/777 (40.54%), Postives = 454/777 (58.43%), Query Frame = 2
Query: 263 TAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKENDQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMN-ERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINFPINKSG-IEAIRKTLEYQKPYWKCLKFYE 2587
T V DEQ+ +WD+ + E P+RL E + + LL+ C+ QA+ + E + HS ++ L+E TQ M +L+ L+ +D V+ N+ + +++GS + ++ AVL +NG +IRPPGHHA S G+C+FN+V +AA+YAQ + +++LIVDWDVHHG TQ+ F VLY SIHRYE G FWP L+ SN+ G +G+GY IN+P N+ M ++DY++ F ++LP+A E+ P+LVL++AGFD+ G P+G M PA FA +TH LM LA G++++ LEGGY + +L + V +L TL G P LE PC S + ++ L+ L FW+ L + E + P LPI L + + RT VYD M NH N S HPE P+R I L + L RC L R A++ E+ HS YV L + H F+SIYI ++ A L+ G +++ V S NG A++RPPGHHAE + GFCFFN+VA+AA +A T ++ +ILIVDWDVHHGNGTQH F + +VLY+SLHRYD+G FFP +G+ S +G GF VN+AWN + D++Y++A+ +V+PI++EFNP+LV+VSAGFDAARGDPLGG V+PE + ++T +L LA+G++IL LEGGYNL IS+ M+ C SLLG P + SG + +I +T++ + YW+ L+ +
Sbjct: 86 TGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHPNSYSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQKHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATPAGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSAQASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPPVLPI------------LTWPVLQSRTG-----------LVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHAL-RILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMK 838 HSP 2 Score: 270.011 bits (689), Expect = 4.089e-73 Identity = 138/365 (37.81%), Postives = 211/365 (57.81%), Query Frame = 2
Query: 257 NKTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQ-LNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHE 1348
++T VYD+ M+ H N+WD+ + E P R+ + E L C+ + + + HS +V + T+ M +L SS D ++ +T + ++ G+ +++AVL NG ++RPPGHHA + A GFC FN+V +AA++AQ ++ +ILIVDWDVHHGN TQ+ F + VLY+S+HRY+ G F+P E IG G G+ +N+ N M ++DYL+ +H ++LPIAYE+NPELVL+SAGFD+A G P G V P +AH+TH LM LA GR++++LEGGY + S+ +S+ +L G PP L P +I ++ +W+SL V ++ E
Sbjct: 479 SRTGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVEDRE 843 HSP 3 Score: 128.257 bits (321), Expect = 2.043e-28 Identity = 88/283 (31.10%), Postives = 132/283 (46.64%), Query Frame = 2
Query: 2615 SPNQTNP------AALDNIVQIDT---NTLAESVRQLGIVEVTFQTEQSIEETLSQPRNDTFITEPNSSNPIIHLPPIVSSDNAVEVPATTSINSTTHATQNISANFLSVDQSS---GATPVSANVSRVINEGNSVGLVLQDIMNLSGVSNSDIHHFLGLTSNDPLPERV--YAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQVFCGRFVQAHMMQHFQNTRHAIVLSFVDLSSWCYECDSYVHNECLNHAKREAHIAKFG--VPQP 3415
+P+QT A LD D TL ++ + + T S + T E +I P S+D+ + P T+ + TT IS + L + G+ A+ S+ E N +G D+ + + + L ++ YAV PL WC HL V P+A +DV C C + +ENW+CL+CYQV+CGR++ HM+QH N+ H +VLS++DLS+WCY C +YVH++ L K AH KFG +P P
Sbjct: 947 TPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDH--QTPPTSPVQGTT---PQISPSTLIGSLRTLELGSESQGASESQAPGEENLLG---------EAAGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAG-LDVTQPCGDCGTIQENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYVHHQALLDVKNIAHQNKFGEDMPHP 1214
BLAST of Histone deacetylase,putative vs. UniProt/SwissProt
Match: sp|Q20296|HDA6_CAEEL (Histone deacetylase 6 OS=Caenorhabditis elegans OX=6239 GN=hda-6 PE=3 SV=2) HSP 1 Score: 484.182 bits (1245), Expect = 3.943e-152 Identity = 282/780 (36.15%), Postives = 424/780 (54.36%), Query Frame = 2
Query: 296 HSNMWDNLYFERPDRLRVCYEGICETNLLEDC-IRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKENDQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMN-ERSIHPESPRRTQMIFEFLRDNSLLSRCKQLE-SRLASKDEIGLIHSPNYVESLGNI-CQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRS--ENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSL--------LGYPTNQIINFP--INKSGIEAIRKTLEYQKPYWKCLKFYE 2587
H N + E DR+ E + +T +LE C + EID+ + +H +S V+ + +++ T + ++D VF N+ + ++ ++ + A NGF ++RPPGHHA GFC+FNNV AA+ A + ++ILIVD DVHHG+ TQ FY+ +VLY SIHR+E G FWP L ES++D+IG+ +G GYN N+ LN+T T+SDYLSI ++LP+A +++P V+ISAGFD+ +G P G M + P ++H+ + L LA+GR++V+LEGGY + +V + L G AP +E + P +S ++ + + L W ++ P LR N+ + E Q E + +T ++ + H + E HPE P RT+ I + LR++ +L +C R+A+ +EI L+H+ +E L + + E+EFNSIY+ + + A + G +L +DE+ + N I+RPPGHHA + GFC FNNVA+AA YA ++ K++LI+DWDVHHGNGTQ F+ + NV+Y+S+HR+D G F+P S VG EG +VN+ ++ + D+EY AF ++MPI+++FNPDLV++SAGFDAA DPLG VTPE F MT L+SLA G++I LEGGYNL IS+ L L Q P I S I+ IR+ Q+ YW LK ++
Sbjct: 26 HENTVCPTHPESSDRILKIKEALTKTKILEKCTVLTNFLEIDDADLEVTHDKSMVKDLMESEKKTQEDINSQCEKYDSVFMTENSMKVAKDGVACVRDLTNRIMANEASNGFAVVRPPGHHADSVSPCGFCLFNNVAQAAEEAFFS-GAERILIVDLDVHHGHGTQRIFYDDKRVLYFSIHRHEHGLFWPHLPESDFDHIGSGKGLGYNANLALNETGCTDSDYLSIIFHVLLPLATQFDPHFVIISAGFDALLGDPLGGMCLTPDGYSHILYHLKSLAQGRMLVVLEGGYNHQISAVAVQRCVRVLLGYAPFSIELNEAPKESTVDSCVSLVSVLRHHWNCF------DYFPSRTSLRLAQWPIVNTKVIYNYDPTTRRADTGEIIQDELASTEFTASDVIPTENMETLIYFNEGDDAHFDLEEDNHPEKPARTRRILKTLRESGVLEKCVDRNCERIATNEEIRLVHTKKMLEHLRTTETMKDEELMEEAEKEFNSIYLTRDTLKVARKAVGAVLQSVDEIFEKDAGQRNALVIVRPPGHHASASKSSGFCIFNNVAVAAKYAQRRHKA--KRVLILDWDVHHGNGTQEIFYEDSNVMYMSIHRHDKGNFYPIGEPKDYSDVGEGAGEGMSVNVPFSGVQMGDNEYQMAFQRVIMPIAYQFNPDLVLISAGFDAAVDDPLGEYKVTPETFALMTYQLSSLAGGRIITVLEGGYNLTSISNSAQAVCEVLQNRSMLRRLREEKEQFATKPQKIESSCIKTIREVCAVQQKYWSILKGFQ 796 HSP 2 Score: 242.662 bits (618), Expect = 6.214e-65 Identity = 119/326 (36.50%), Postives = 197/326 (60.43%), Query Frame = 2
Query: 260 KTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEI-DNELIYYSHSQSHVQLIEDTQTMT-AIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRA--KNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKA 1225
+T ++E H ++ ++ + E+P R R + + E+ +LE C+ + I NE I H++ ++ + T+TM ++E + + ++ +T + + G+ ++ + + + A +N ++RPPGHHA S++SGFCIFNNV +AAKYAQ + +++LI+DWDVHHGN TQ FY S V+Y+SIHR++ GNF+P +Y +G G G ++N+P + M +++Y F +I+PIAY++NP+LVLISAGFD+A+ P G V P FA MT++L LA GR++ +LEGGY + S+ +S L ++
Sbjct: 426 ETLIYFNEGDDAHFDLEEDNHPEKPARTRRILKTLRESGVLEKCVDRNCERIATNEEIRLVHTKKMLEHLRTTETMKDEELMEEAEKEFNSIYLTRDTLKVARKAVGAVLQSVDEIFEKDAGQRNALVIVRPPGHHASASKSSGFCIFNNVAVAAKYAQRRHKAKRVLILDWDVHHGNGTQEIFYEDSNVMYMSIHRHDKGNFYPIGEPKDYSDVGEGAGEGMSVNVPFSGVQMGDNEYQMAFQRVIMPIAYQFNPDLVLISAGFDAAVDDPLGEYKVTPETFALMTYQLSSLAGGRIITVLEGGYNLTSISNSAQAVCEVLQNRS 751 HSP 3 Score: 112.464 bits (280), Expect = 9.504e-24 Identity = 54/111 (48.65%), Postives = 66/111 (59.46%), Query Frame = 2
Query: 3086 VYAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQVFCGRFVQAHMMQHFQNTRHAIVLSFVDLSSWCYECDSYVHNECLNHAKREAHIAKFGVPQPS 3418
+AV PL C HL +V+ P A +I+ +C+ C E W CLTCY+ CGRFV H M H ++ H + LS DLS WCY CDSYVHN L AK AH +KFG PS
Sbjct: 846 AHAVVPLATCPHLKEVKPLPPA-KINARTACSECQIGAEVWTCLTCYKYNCGRFVNEHAMMHHLSSSHPMALSMADLSVWCYPCDSYVHNPALIGAKSAAHESKFGETMPS 955
BLAST of Histone deacetylase,putative vs. UniProt/SwissProt
Match: sp|Q6P3E7|HDA10_MOUSE (Polyamine deacetylase HDAC10 OS=Mus musculus OX=10090 GN=Hdac10 PE=2 SV=2) HSP 1 Score: 341.658 bits (875), Expect = 4.170e-102 Identity = 169/381 (44.36%), Postives = 233/381 (61.15%), Query Frame = 2
Query: 263 TAFVYDEQMLLHSNMWDN--LYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVA-----DNHEPYPEYLRHLPES 1384
TA VY E M +WD+ E P+RL +G+ + L E C+ + A E E + HS ++ L++ TQT+ +L LS Q++ V+F +T + ++AG+ ++++ AVL NG L+RPPGHH+ + A+GFC+FNNV +AAK+A+ Y Q+ILIVDWDVHHG QY F + VLY S HRYE G+FWP L ES+ D +G +G+G+ +N+P N+ M N+DYL+ F ++LP+A+E++PELVL+SAGFDSAIG PEG M P CFAH+T L LA GR+ +LEGGY +ESL SV + + TL G P L PC S E+IQ+ +W SL NVA H P LR L ES
Sbjct: 3 TALVYHEDMTATRLLWDDPECEIECPERLTAALDGLRQRGLEERCLCLSACEASEEELGLVHSPEYIALVQKTQTLDKEELHALSKQYNAVYFHPDTFHCARLAAGAALQLVDAVLTGAVHNGLALVRPPGHHSQRAAANGFCVFNNVALAAKHAKQKYGLQRILIVDWDVHHGQGIQYIFNDDPSVLYFSWHRYEHGSFWPFLPESDADAVGQGQGQGFTVNLPWNQVGMGNADYLAAFLHVLLPLAFEFDPELVLVSAGFDSAIGDPEGQMQATPECFAHLTQLLQVLAGGRICAVLEGGYHLESLAQSVCMMVQTLLGDPTPPLLGLMVPCQSALESIQSVQTAQTPYWTSLQQNVAPVLSSSTHSPEERSLRLLGES 383 HSP 2 Score: 283.493 bits (724), Expect = 3.570e-81 Identity = 138/357 (38.66%), Postives = 221/357 (61.90%), Query Frame = 2
Query: 1577 ESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTI----YHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINFPIN-KSGIEAIRKTLEYQKPYWKCLKFYEPLVVTYTEISPNQTN 2632
E P R + LR L RC L + AS++E+GL+HSP Y+ + Q++ T+ H +++N++Y + ++ A L+ G L ++D V + NG A++RPPGHH++ GFC FNNVA+AA +A KY +++ILIVDWDVHHG G Q+ F + +VLY S HRY++G F+P + AVG +GF VN+ WN+ + +++Y++AF+++++P++ EF+P+LV+VSAGFD+A GDP G + TPECF ++TQ+L LA G++ LEGGY+L ++ + V +LLG PT ++ + +S +E+I+ Q PYW L+ V++ + SP + +
Sbjct: 26 ECPERLTAALDGLRQRGLEERCLCLSACEASEEELGLVHSPEYI----ALVQKTQTLDKEELHALSKQYNAVYFHPDTFHCARLAAGAALQLVDAVLTGAVHNGLALVRPPGHHSQRAAANGFCVFNNVALAAKHAKQKYG--LQRILIVDWDVHHGQGIQYIFNDDPSVLYFSWHRYEHGSFWPFLPESDADAVGQGQGQGFTVNLPWNQVGMGNADYLAAFLHVLLPLAFEFDPELVLVSAGFDSAIGDPEGQMQATPECFAHLTQLLQVLAGGRICAVLEGGYHLESLAQSVCMMVQTLLGDPTPPLLGLMVPCQSALESIQSVQTAQTPYWTSLQQNVAPVLSSSTHSPEERS 376
BLAST of Histone deacetylase,putative vs. UniProt/SwissProt
Match: sp|Q969S8|HDA10_HUMAN (Polyamine deacetylase HDAC10 OS=Homo sapiens OX=9606 GN=HDAC10 PE=1 SV=1) HSP 1 Score: 340.117 bits (871), Expect = 1.497e-101 Identity = 159/355 (44.79%), Postives = 223/355 (62.82%), Query Frame = 2
Query: 263 TAFVYDEQMLLHSNMWDN--LYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSL 1321
TA VY E M +WD+ ERP+RL + + + L + C+R+ A+E E + HS +V L+ +TQ + +L+ LS Q D ++F +T + ++AG+ ++++ AVL +NG L+RPPGHH + A+GFC+FNNV IAA +A+ + +IL+VDWDVHHG QY F + VLY S HRYE G FWP LRES+ D +G +G G+ +N+P N+ M N+DY++ F ++LP+A+E++PELVL+SAGFDSAIG PEG M P CFAH+T L LA GRV +LEGGY +ESL +SV +T+ TL G P L PC S E+IQ+ WKSL
Sbjct: 3 TALVYHEDMTATRLLWDDPECEIERPERLTAALDRLRQRGLEQRCLRLSAREASEEELGLVHSPEYVSLVRETQVLGKEELQALSGQFDAIYFHPSTFHCARLAAGAGLQLVDAVLTGAVQNGLALVRPPGHHGQRAAANGFCVFNNVAIAAAHAKQKHGLHRILVVDWDVHHGQGIQYLFEDDPSVLYFSWHRYEHGRFWPFLRESDADAVGRGQGLGFTVNLPWNQVGMGNADYVAAFLHLLLPLAFEFDPELVLVSAGFDSAIGDPEGQMQATPECFAHLTQLLQVLAGGRVCAVLEGGYHLESLAESVCMTVQTLLGDPAPPLSGPMAPCQSALESIQSARAAQAPHWKSL 357 HSP 2 Score: 282.722 bits (722), Expect = 7.916e-81 Identity = 140/355 (39.44%), Postives = 217/355 (61.13%), Query Frame = 2
Query: 1577 ESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINFPIN--KSGIEAIRKTLEYQKPYWKCLKFYEPLVVTYTEISPNQTNP 2635
E P R + LR L RC +L +R AS++E+GL+HSP YV + +F++IY + ++ A L+ G L ++D V + +NG A++RPPGHH + GFC FNNVAIAA +A K+ + +IL+VDWDVHHG G Q+ F + +VLY S HRY++G F+P + AVG GF VN+ WN+ + +++Y++AF+++++P++ EF+P+LV+VSAGFD+A GDP G + TPECF ++TQ+L LA G+V LEGGY+L +++ + V +LLG P ++ P+ +S +E+I+ Q P+WK L+ + VT +SP+ +P
Sbjct: 26 ERPERLTAALDRLRQRGLEQRCLRLSAREASEEELGLVHSPEYVSLVRETQVLGKEELQALSGQFDAIYFHPSTFHCARLAAGAGLQLVDAVLTGAVQNGLALVRPPGHHGQRAAANGFCVFNNVAIAAAHAKQKHG--LHRILVVDWDVHHGQGIQYLFEDDPSVLYFSWHRYEHGRFWPFLRESDADAVGRGQGLGFTVNLPWNQVGMGNADYVAAFLHLLLPLAFEFDPELVLVSAGFDSAIGDPEGQMQATPECFAHLTQLLQVLAGGRVCAVLEGGYHLESLAESVCMTVQTLLGDPAPP-LSGPMAPCQSALESIQSARAAQAPHWKSLQQQD---VTAVPMSPSSHSP 374
BLAST of Histone deacetylase,putative vs. TrEMBL
Match: A0A0X3PKU1 (UBP-type domain-containing protein OS=Schistocephalus solidus OX=70667 GN=TR96205 PE=4 SV=1) HSP 1 Score: 880.937 bits (2275), Expect = 0.000e+0 Identity = 482/1149 (41.95%), Postives = 671/1149 (58.40%), Query Frame = 2
Query: 179 FGDEDLPAAQSNHGLYDNIELRINFPNKTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKENDQLNHKIYELR---TKNAFNNYPNKTCFVYDCRMENHMNERSIH-PESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLAN------------GKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINFPI--NKSGIEAIRKTLEYQKPYWKCLKFYEPL--------------VVTYTEISPNQTNPAALDNIVQI--DTNTLAESVRQLGIVEVTFQTEQSIEETLSQPRNDTFITE---------PNSSNPIIHLPPIVSSDNAVEVPATTSINSTTH---ATQNISANFLSVDQSSGATPV------SANVSRVINE-------------GNSV----GLVLQDIMNLSGVSNSDIHHFLGLTSNDPLPERVYAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQVFCGRFVQAHMMQHFQNTRHAIVLSFVDLSSWCYECDSYVHNECLNHAKREAHIAKFGVPQPS 3418
FGDED+ + G+ RI TA + ML H++ Y E P RL+ +E + L + C+ +Q + +EL+ Y+HSQ ++ + T TM+ + ++ DC F+ T A+ +S G+ + +V+ +N CL RPPGHHAM +EA GFC+FNNV IAAK+A ++LIVDWDVHHG ATQY FYN +KVLY SIHRY+DG FWPKLRESNYD++G G GYNINIPLN T++DYL+IF+ +++PIAYE++P+L+L+SAG+D A+GCP G + P+ FAH+TH+LM LA G+VVV LEGGY ESL DSV T+ATL G P LE IQNC+ L WK LS+ N P + + L ++W P +E+ +E K+ +LR T + +N N+ C VYD RMENH +E H PE P R + +E L + L RCK+ E+R+A++DE+ +H +YV+ + + S + F+SIY N+HSY SA+L+ G LL+V+D++C+ + +G A+IRPPGHHAE + GFCFFNNVA+A +A + K+I +VDWDVHHGNG QH+F + +VLYIS+HR+D+G FFPGS D + +AVG EG N+ WN RPVRD +YI+AF++ V+P+ +EF P+L ++AGFDAARGD LGG V+PECFG+MT +LT++A G +ILALEGGYNL V S+ +SHCV+SLLG T +N I + AIR+T+E + YWK L Y P+ VT ++ + T PA + V D L + + E + E TL+ + T E P ++ + LP S+ + E + ++ + H T ++ + S A+ V SA+ S V + G+S+ G L +++ S D+ F GL S+D LPER++AV+P+LWC HL V S SA D+N +CT CP+ ENW+CLTCYQV+CGR+ HM++HF TRH IVLSF DLS+WCY C+SYVHNE L AKR AH+AKFG P+
Sbjct: 57 FGDEDIQVVFAGLGINSMFHRRIASSRGTALYFHGDMLKHAHQVHENYPEHPGRLKSIHEKCVDRGLFDRCLTMQPELATDELLRYAHSQEYINEVAATATMSPEAREAYITKFDCAVFNEFTNRAARLSVGALTNAVDSVMRGDVRNAICLTRPPGHHAMNAEACGFCVFNNVEIAAKFAIDRTEANRVLIVDWDVHHGQATQYAFYNDNKVLYFSIHRYDDGAFWPKLRESNYDFVGEGRGYGYNINIPLNGPGYTDNDYLTIFNCLLMPIAYEFDPDLILVSAGYDCALGCPLGCFSLTPSVFAHLTHRLMALADGKVVVTLEGGYNTESLADSVANTVATLLGDPLPSLEAVAPVKPGTVTAIQNCVSMLRTRWKCLSLFPISNAVPLKD-MSDLSTNSWKKVMEPFTGVEEFGLTPEELAIATAKVVDLRQVHTPFSIDN-SNRVCLVYDSRMENHKSETDRHQPECPARIRRAYELLEEYGLARRCKRTEARVATRDELLRVHDADYVDLIEQTSRLSQADLNEAGSVFDSIYFNKHSYDSAVLAVGSLLSVVDDICNCEALHGVAVIRPPGHHAEKDSCAGFCFFNNVALAVRHAQEIHDR--KRIAVVDWDVHHGNGIQHEFEEDPSVLYISMHRFDDGKFFPGSQDAAATAVGTGAGEGKTANLPWNSRPVRDGDYITAFLHFVLPLLYEFRPELTFIAAGFDAARGDHLGGFGVSPECFGHMTHLLTAIATLNPSTDGSGSHRGGLILALEGGYNLAVTSEALSHCVASLLG-DTCLRLNSGIAPTERSCRAIRRTVEVHRKYWKSLFNYSPITCYCDADTLSRWQAAVTSSQTAGVSTQPATEVSTVTFTADAGCLTSQAHADMRLTQSLSIENTSESTLTPTPSWTGGLELVSVGIPVVPETALASVLLPTDASTPPSSEPTQSMNVPESVHEGNETSHVLTTTATATSVSHASTVPRPPEPSASTSHVQRDDEVPSDTAPAAAAGSSMSVPQGSSLNEVVQFVNTSIDDVPAFFGLNSDDRLPERIFAVEPILWCAHLQSV-TSASAWHPDINGTCTSCPNRGENWVCLTCYQVYCGRYASGHMLEHFSATRHPIVLSFADLSAWCYICNSYVHNEVLLEAKRAAHLAKFGERMPT 1199
BLAST of Histone deacetylase,putative vs. TrEMBL
Match: A0A210QHS9 (Histone deacetylase 6 OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT11824 PE=4 SV=1) HSP 1 Score: 843.573 bits (2178), Expect = 0.000e+0 Identity = 439/1077 (40.76%), Postives = 630/1077 (58.50%), Query Frame = 2
Query: 254 PNKTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHE---PYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKE-----------------NDQLNHKIYELRTKNAFNNYPNKTCFVYDCRME-NHMNERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINFPINKSGIEAIRKTLEYQKPYWKCLKFYEPLVVTYTEISPNQTNPAALDNIVQIDTNTLAESVRQLGIVEVTFQTEQSIEET----LSQPRNDTFITEPNSSNPIIHLPPIVSSDNAVEVPATTSINSTTHATQNISANFLSVDQSSGATPVSANVSRVINEGNSVGLVLQDIMNLSGVSNSDIHHF-LGLTSNDPLPERVYAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQVFCGRFVQAHMMQHFQNTRHAIVLSFVDLSSWCYECDSYVHNECLNHAKREAHIAKFGV 3406
P T VYD++M +WD + E+P+R+ + E L+E C RI+A+ + + H+++H++ +++T M+ LK++S+++D ++ T AS ++ GST+E+++ +L + +NG +IRPPGHHAM E G+C FN V IAAK+A +++LIVDWDVHHG ATQ FY+ +VLY SIHRYE G +WP LRES+YD+IG +G+GYN+N+PLNK +MT++DYL+IFH I++PIA++++P+LVL+S+G+D+AIGCPEG M V P +AHMTH LM LA GRV + LEGGYC++SL ++V LTL +L G P L +P S+ TI N +K L +W S E PY E P+ P +P NK KE + + I +L + PNKTC VYD M +H HPE P R IF+ + LL RC +++SRLA+ E IHS +Y+E + + P + FNSIY+ S + A ++ G +L+V + V S ++++G A++RPPGHHAE +GFCFFN+VAIAA YA K+ +K++LI+DWDVHHGNGTQH F+ + ++L+ISLHR+D+G F+P STDG+ + G +GFNVNI +N+ P D+EY +AF IVMPI++EF P+LV+VSAGFDAA GDPLGG +TP +G+MT ML+SLANG+V+LALEGGYNL+ IS+ M+ C S LLG P + +S ++ I TL+ K +WKCLKF E + + + + + E +++ V V + QS EE S+P T T N + S P T+ + T + + GA +A+++ + G L ++M G +++ + + D ER+YAVQPL WC HL VQ P +D A C C + ENW+CL CY+VFC R+V HM+ H +H + LSF DLS WCY CD+Y+ N+ +N AKR AH KFG
Sbjct: 88 PEGTGLVYDDRMATFECLWDPAFPEKPERITESFARCSELGLIERCTRIEAQYGTEDQVLIQHTEAHLEKLKETVDMSKEALKKVSAKYDSIYIHQATYEASLLALGSTMELMEQILKKKVRNGLAIIRPPGHHAMNEEFCGYCFFNQVAIAAKHAVDTLGLKRVLIVDWDVHHGQATQQMFYDDPRVLYFSIHRYEYGKYWPNLRESDYDFIGDGKGKGYNVNVPLNKVHMTDTDYLAIFHQILMPIAHQFSPDLVLVSSGYDAAIGCPEGEMLVSPVTYAHMTHMLMSLAEGRVCICLEGGYCIKSLSEAVALTLRSLLGDPCPALPAMGDPSHSITTTILNVIKVLQPYWNCFSYQTELALEESCPYEEVNDMPPK--------PGMPFVTEENKPKEYTIMYEYEDGVEEEYIIQHKFDAVIDQLIADTSLAVPPNKTCIVYDEGMRVHHAITFRGHPEDPDRVTCIFDKHAEWGLLDRCLRVQSRLATDGETQAIHSSSYLEQMQASAELPPMELRNLQHSFNSIYMCPESNVCARMAAGCVLSVTEAVLSGQAKSGVAVVRPPGHHAECTKAMGFCFFNSVAIAAKYAQNKF--GLKRVLILDWDVHHGNGTQHSFYDDPSILFISLHRFDHGSFYPTSTDGNHNMTGSGAGKGFNVNIPFNEGPKGDAEYKAAFQQIVMPIAYEFAPELVLVSAGFDAALGDPLGGYHITPAGYGHMTHMLSSLANGRVVLALEGGYNLSSISNSMATCTSVLLGDPCPYLPYVQPQESAVKGINNTLDSHKQFWKCLKFRESIPDLRCKEGEGEPEGIEEQKEEEKFKKNIEELSKKMTSVSVYDRAAQSPEEAKSANKSEPEVTTQATSTNDKD---------SGSVGDATPTTSETKPSVTETTPTPSKSSDTMEDQGAVGGAASMAVGGSSVGGAGTPLNEMMGAVGGADNLLQALTVAQALEDMGVERMYAVQPLTWCPHLQTVQPLPQGI-LDTRAPCQDCGNEGENWICLVCYKVFCSRYVNEHMVIHGATEQHLVTLSFSDLSVWCYGCDNYIDNQVVNAAKRAAHRHKFGT 1144
BLAST of Histone deacetylase,putative vs. TrEMBL
Match: A0A1S3JEN4 (LOW QUALITY PROTEIN: histone deacetylase 6-like OS=Lingula unguis OX=7574 GN=LOC106172630 PE=4 SV=1) HSP 1 Score: 832.402 bits (2149), Expect = 0.000e+0 Identity = 441/1097 (40.20%), Postives = 631/1097 (57.52%), Query Frame = 2
Query: 263 TAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQ-------------------------------------LKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSL---------SVNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKEND---QLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMNERSI-HPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINFPINKSGIEAIRKTLEYQKPYWKCLKFYEPLVVTYTEISPNQTNPAALDNIVQIDTNTLAESVRQLGIVEVTFQTEQSIEETLSQPRNDTFITEPNSSNPIIHLPPIVSSDNAVEVPATTSINSTTHATQNISANFLSVDQSSGATPVSANVSRVINEGNSVGLVLQDIMNLSGVSNSDIHHFLGLTSNDPLPERVYAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQVFCGRFVQAHMMQHFQNTRHAIVLSFVDLSSWCYECDSYVHNECLNHAKREAHIAKFG 3403
T +YD M H WD L+ E PDR+ Y + L+ C+ I K+ +E HS +++L++D+Q ++ IQ L++LS ++D ++F++ T + +S GSTIE+ + +L ++ +NGF ++RPPGHHAM EA G+C FNNV IAAK A + +++LIVDWDVHHG TQY FY+ +V+Y+SIHRYE GNFWP LRES+YDYIG G GYNINIPLNKT MTNSDY+++FH +++PI YEYNP+LVL+S+G+D+AIGCPEG M+V PAC+AH + L LA G++ V+LEGGYC++SL + V LTL L G P++ +P D +K+TI N ++ L +W+ L S V+ + E+LR +P ST ++ PI++ +E + + +I EL P++T VYD M H N HPE P R I+ +++ LL C ++ESR+A+ +E+ H + + + I + P + ++NS+Y+ Q SY ALL+ G LLNV++ V +++S+NG A+IRPPGHHAE+N GFC FNNVAIAA YA + +KK+LI+DWDVHHGNG QH F + +VLYIS+HRYD G FFP DG+ VG GFN+NI WNK + D+EYI+AF+ ++MP+++EF+PDLV+VSAGFDAARGDPLG +TP +G+MTQML SLANG+VILALEGGYNL+ IS+ M+ C LLG + + +E+I L+ K YWKCL+F L ++ A + N T+ + +G ++V +++ S + S + P + SSD +G +P+ A + L +++++ + D+ F + PLP WCEHL V P +DV A+C++C ST+ENW+CLTCY+V CGR+V HM+ H +T H +VLS+ DLS WCY CD+Y+HNE + KR AH +KFG
Sbjct: 127 TGLIYDHFMTQHRCEWDLLHPECPDRITEPYLRCLQYGLVTRCVPILPKKSVDEAALSQHSPEYLKLLKDSQFLSEIQPLQDLSEKYHGIYFNSPKMTSEKGHLPEHFLPRGVQTLQDLSGKYDSIYFNSKTFECAQLSLGSTIEMTEQILQEKVRNGFAIVRPPGHHAMYKEACGYCFFNNVAIAAKRALDKFGLERVLIVDWDVHHGQGTQYMFYDDPRVMYVSIHRYEYGNFWPNLRESDYDYIGEGRGTGYNINIPLNKTGMTNSDYMAVFHQLLMPIFYEYNPQLVLVSSGYDAAIGCPEGEMEVTPACYAHFINMLSALADGKLAVILEGGYCLKSLSEGVALTLRALLGDPTPRIGPLQQPNDVIKKTILNAIRVLRPYWQCLQFQGVLPVQSAEVSSTTQE-DEHLRTVPFST-PENRPEVYPIDECCYPVQEPEVKATYSARIQELIDNTYLGKAPHRTALVYDEVMRKHKNHVDPGHPERPDRITKIYNKIQEYRLLKHCLRVESRMATDEEVLTCHKTEHFKKMQQIKETKPRELKEVQLQYNSVYLCQESYDCALLAVGSLLNVVEAVLTNKSQNGVAVIRPPGHHAEINQACGFCLFNNVAIAARYAQKTF--GVKKVLILDWDVHHGNGIQHIFEDDPSVLYISIHRYDQGFFFPAGPDGNYDKVGNGAGAGFNINIPWNKYGMGDAEYIAAFLQVIMPVAYEFDPDLVLVSAGFDAARGDPLGHCDITPAGYGHMTQMLMSLANGRVILALEGGYNLHSISESMAMCTKVLLGGTCPPLGSLVPKTMAVESICNVLDTHKKYWKCLQFRVDLPAPVLPVT------AGVQNNAVTSTSDMDSLTTAIGALQVKYESVSSSSDGGSF----------------LSSPTVTSSD------------------------------CTGDSPLGA-----CGGSEAKNLTVRELLGGALADQDDLQMFAVV----PLP----------WCEHLKMVAPPPERG-LDVFAACSMCESTKENWVCLTCYEVCCGRYVNEHMLFHGLSTEHKMVLSYSDLSVWCYGCDAYIHNEIIVPHKRAAHRSKFG 1147 HSP 2 Score: 317.775 bits (813), Expect = 5.272e-87 Identity = 157/371 (42.32%), Postives = 229/371 (61.73%), Query Frame = 2
Query: 221 LYDNIELRINFPNKTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNV 1333
L DN L P++TA VYDE M H N D + ERPDR+ Y I E LL+ C+R++++ +E + H H + ++ + +LKE+ Q++ V+ + + ++ GS + V++AVL ++++NG +IRPPGHHA ++A GFC+FNNV IAA+YAQ + +K+LI+DWDVHHGN Q+ F + VLYISIHRY+ G F+P + NYD +G G G+NINIP NK M +++Y++ F +I+P+AYE++P+LVL+SAGFD+A G P G D+ PA + HMT LM LA GRV++ LEGGY + S+ +S+ + L G P L P E+I N L +WK L V
Sbjct: 579 LIDNTYLG-KAPHRTALVYDEVMRKHKNHVDPGHPERPDRITKIYNKIQEYRLLKHCLRVESRMATDEEVLTCHKTEHFKKMQQIKETKPRELKEVQLQYNSVYLCQESYDCALLAVGSLLNVVEAVLTNKSQNGVAVIRPPGHHAEINQACGFCLFNNVAIAARYAQKTFGVKKVLILDWDVHHGNGIQHIFEDDPSVLYISIHRYDQGFFFPAGPDGNYDKVGNGAGAGFNINIPWNKYGMGDAEYIAAFLQVIMPVAYEFDPDLVLVSAGFDAARGDPLGHCDITPAGYGHMTQMLMSLANGRVILALEGGYNLHSISESMAMCTKVLLGGTCPPLGSL-VPKTMAVESICNVLDTHKKYWKCLQFRV 947
BLAST of Histone deacetylase,putative vs. TrEMBL
Match: A0A3Q0KMY1 (Histone deacetylase,putative OS=Schistosoma mansoni OX=6183 PE=4 SV=1) HSP 1 Score: 824.698 bits (2129), Expect = 0.000e+0 Identity = 452/1151 (39.27%), Postives = 670/1151 (58.21%), Query Frame = 2
Query: 179 FGDEDLPAAQS--NHGLYDNIELRINFPNKTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYA--QLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSV-NVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKENDQLNHKIYELRTKN--AFNNYPNKTCFVYDCRMENHMNERS-IHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLA-------------------------------------NGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQI-INFPINKSGIEAIRKTLEYQKPYWKCLKFYEPLVVTYTEISPNQTNPAALDNIVQ-------------------IDTNTLAESVRQLGIVEVTFQTEQSIEETLSQP--RNDTFITEPNSS--NPIIHLPPIVSSDNAVEVPATTSINSTTHATQNISANFLSVDQSSGATPVSANVSRVINEGNSVGLVLQDIMNLSGVSNSDIHHFLGLTSNDPLPERVYAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQVFCGRFVQAHMMQHFQNTRHAIVLSFVDLSSWCYECDSYVHNECLNHAKREAHIAKFGVPQPSNS 3424
D+D+P S ++ +D + + + TAF+YDE+MLLH N+W + E P+R + LL C+ I + ++ + H +++ I+ T TM +LK+LS+ D V+F+ +T L++ +S GS I+ + + +N FCL+RPPGHHA+ +EA GFCI+NNV IAA YA +LNY+ +ILIVDWDVHHGN TQY FY+ KVL+ISIHRY++G FWP LRESNYD+IG GRG+N+NI LN ++ +SDYL+IFH I+LP+AYE++PELVL+SAG+DS+ GCP G +++ P+ +AH+THKLM A G+V+V LEGGY +++L +SV TL+ L G P L+ SV ETI NC+ L F WK L + + +++ +P+ + HL +W+ KVP D + ++ + + L+ + A NN + TC VYD RM+NH NE +PE+P R + + L+ L RCK +E+R A++ E+ +H+ YV ++ + T + F NS+Y N H+Y +ALL+ G LL VIDEVCS S NG A+IRPPGHHA + +GFCFFNNVAI A +A Y +++I I+DWDVHHGNGT F + N+LYIS+HR+D+G +FP S S G + G ++IAWN R V+D +YI F NI++PI +EF P L++VSAGFDAA GD LG L V+PECF ++T +L ++ +G ++LALEGGY + +S C++HCV++LLG ++ N I++ +++++T+E YW LK ++P+ Y + S + P N Q I+ N ++ V + + +Q I + S P N+ + + S + L S +N + ++TSI+ Q + ++ + V+ VI+ S N SG ++ DIH F GL S+ L +V+AV PL WC HL V +P+ + D+N+ C C + ENW+CL+CY V+CGR+ +HM++HF T+H+IVLS+ DLS+WCY+C+SYVHNE L + KR + AKFG P +S
Sbjct: 22 LSDKDIPVIFSAFDNSRHDYFDKQSSHDKGTAFIYDERMLLHKNIWFPNFLECPERFSATIDKCTTYGLLSRCLIINPEPATDDFLTLYHQTEYIEQIKQTTTMEDNELKQLSATLDSVYFNKHTDLSARLSVGSWIQAVDLIHHGDVRNAFCLVRPPGHHALTNEACGFCIYNNVAIAANYAIEKLNYN--RILIVDWDVHHGNTTQYAFYDNPKVLFISIHRYDNGEFWPNLRESNYDFIGTGRGRGFNVNIALNDKDIGDSDYLTIFHRIVLPLAYEFDPELVLVSAGYDSSFGCPVGQLNLSPSLYAHLTHKLMAFAEGKVIVGLEGGYYLDTLSESVGHTLSALLGDPMPSLDPMKPINPSVLETISNCISTLSFRWKFLHIYPLLNDNVLFPD-ISHLKLQSWSDVKVPNFEPTDEHHNVEDKLGIEKRFDYLKNTHPIAGNNKISGTCLVYDNRMQNHKNEEDPTYPENPERIKHTYALLKQLGLKRRCKCIEARYATRTELLRVHTEEYVNTIASTVNMEQTALNDFGASENSVYFNCHTYDNALLASGSLLAVIDEVCSGESLNGMALIRPPGHHALKDRCMGFCFFNNVAIGARHAQQVY--GLERIAIIDWDVHHGNGTAEIFEDDPNILYISVHRFDHGRYFPNSDFSSSQFCGTGEGLGRTIHIAWNGRDVKDGDYIVTFTNIIIPILYEFRPQLILVSAGFDAAHGDKLGRLGVSPECFAHLTHLLMTVVHLNPSVYTLNHRKNSPIISTPTRQTRQRLQQEKSISYSGGLVLALEGGYQITALSQCVAHCVATLLGDNCPRLSSNLSISEKSCKSMQQTIEIHSNYWNMLKGFDPVNRFYDQDSIRR--PVIGRNTRQNPQNTTTTTISSSSSSNTTIELNNESDLVHS-KLNNLCLNDKQPITKCTSTPGDNNNNHLDDEFSQLFKTKLTLNADSSLNNTSDRLSSTSISKHPSERQYVHEQNSYETLNNSESTVAKTSGVVIDPSESHHQQQPSTSNGSGFTSEDIHDFFGLPSSHELTSQVFAVTPLSWCPHLISVHNNPNW-KPDINSLCNSCNHSNENWVCLSCYSVYCGRYANSHMIEHFNITKHSIVLSYADLSTWCYQCESYVHNEVLLNMKRAVYQAKFGEVMPGSS 1163
BLAST of Histone deacetylase,putative vs. TrEMBL
Match: A0A158QH17 (UBP-type domain-containing protein OS=Rodentolepis nana OX=102285 GN=HNAJ_LOCUS1265 PE=4 SV=1) HSP 1 Score: 819.305 bits (2115), Expect = 0.000e+0 Identity = 433/1094 (39.58%), Postives = 633/1094 (57.86%), Query Frame = 2
Query: 179 FGDEDLPAAQSNHGLYDNIELRINFPNKTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKENDQLNHKIYELRTKNAFNNYPN--KTCFVYDCRMENHMNERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANG------KVILALEGGYNLNVISDCMSHCVSSLLGYPTNQI--INFPINKSGIEA-------IRKTLEYQKPYWKCLKFYEPLVVTYTEISPNQTNP-AALDNIVQI----DTNTLAESVRQLGIVEV-TFQTEQSIEETLSQPRNDTFITEPNSSNPIIHLPPIVSSDNA----------VEVPATTSINSTTHATQNISANFLSVDQSSGATPVSANVSRVINEGNSVGL-VLQDIMNLSGVSNSDIHHFLGLTSNDPLPERVYAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQVFCGRFVQAHMMQHFQNTRHAIVLSFVDLSSWCYECDSYVHNE 3358
FGDED+ + G+ N + R+N +TA ML HSN + E PDRLR ++ + E LL C+ IQ I EL+ + H+QS++ + T+ M + + DC +F +T +A+ ++AGS + V +N FCL+RPPGHHAM+ EA G+C+FNNV IAAK+A +ILIVDWD+HHG TQY FYN SKVLY SIHRY++G +WP LRES+YD++G + GYNIN+PLN + T+ DYL+IF+ +++PIAYE+ P+LV+ISAG+D A+GCP G + PA FAH+T +LM LA G+++ LEGGY +E+L D V T++ L G P L+ +E I+NC+ L WK L V + P + L L ++W + VP ++ E K+ ELR F + + C VYD RMENH E+ + E P RT+ +E L + L RC++ ++RLA+ DE+ IH+P Y++ L S + ++F +Y+N+H++ SA L+ G LL VID+VC+ S +G A+IRPPGHHAE + +GFCFFNN+A+A +A + +++KI +VDWD+HHGNG Q F + +VL+IS+HR+D G F S+D S VG + EG N+NI WN R +RD ++I+AF +IV+P +EF PDLVIV+AGFD RGD LGG++V+ ECFG++T L A+ ++LALEGGYN+NV S+ +SHCV+SLL P ++ P GI + +T P+ + T S T P A N+ I T+ AES L V + T+ E + N +F +I L P + + + PA+ S+ ++T +Q + +S + PV S + + + L ++ ++ S V D++ FLGL S DP+P+R++AV+P LWC HL+ V +S D+N C+ C + +ENW+CLTCY+V+CGR+ Q HM+QH+ ++H IVLS DLS+WCY C+ Y+HNE
Sbjct: 22 FGDEDVQVVFAGLGISSNFQRRLNSSRRTALFCHNDMLKHSNPLHDDCPECPDRLRSTFQKLIEYELLRRCLLIQPSAIGTELLRFIHAQSYIDAVASTEEMADSARHQFMQKFDCAYFSKDTNIAARLAAGSLTHAVDIVTRGDVRNAFCLVRPPGHHAMKDEACGYCVFNNVAIAAKHALTQLVANRILIVDWDIHHGQGTQYAFYNDSKVLYFSIHRYDNGEYWPSLRESDYDFVGQGQSYGYNINVPLNGKDYTDIDYLTIFNVLLMPIAYEFGPDLVIISAGYDCALGCPYGGFILSPAVFAHLTSRLMALADGKLICALEGGYGLETLSDCVAHTVSALLGDPLPTLDPLKPLHPGTREAIRNCVSVLRAKWKCLGVFPINQSLPLKD-LSSLALNSWKTVMVPSTAVDPFERSESELSADKAKLEELRKSYRFTALTDLERVCLVYDSRMENHKPEQERYLECPNRTRRAYELLEEYGLARRCRRTDARLATDDELLRIHTPEYIDELKKTASMSQNEIDEYAKQFQWVYMNKHTFDSASLAGGSLLAVIDDVCNGESLHGVAVIRPPGHHAERDCCMGFCFFNNIALAVRHA--QEVHNLQKIAVVDWDIHHGNGIQRIFDDDPSVLFISIHRFDGGQFLQNSSDASADHVGVGEGEGTNINIPWNGRNLRDGDFIAAFFHIVLPTLYEFRPDLVIVAAGFDVVRGDHLGGVSVSVECFGHLTHHLMGAASALSSRRCGLVLALEGGYNINVTSEALSHCVASLLSDPCVRLPGSQVPTENHGIFLSGPLNCHLDQTTVSTNPFITTNSTITVGNTSTTRASSETTIPLTATPNVTTIASFESTDFSAESSFLLHTVSISTYPMETT---------NASFTATDYQQEEVITLSPTPAHNEEHFLLLTKLFNLAYPASQSLLTSTQPSQPQPS--VSTLTPTADAPVPGP-STAHSSSSQISLDAMRQLVEFSDVGIEDLNTFLGLNSTDPVPDRLFAVEPSLWCPHLDLV-ESAGQWRPDINRPCSRCDNRQENWVCLTCYEVYCGRYAQGHMLQHYNTSQHPIVLSLADLSAWCYVCNGYIHNE 1099 HSP 2 Score: 332.798 bits (852), Expect = 2.183e-90 Identity = 173/423 (40.90%), Postives = 248/423 (58.63%), Query Frame = 2
Query: 248 NFPNKTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIA-----------------AKYAQLNYST-----------QKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNP 1432
F T +DE+M H + W E P+R+ + + + L+ C R+ A+ +E + HS+ +++L++ + M +L LS +D VFF+++T AS ++AGS E+ + + + NG L+RPPGHHAM EA G+CIF NV IA +K L +T ++ILI+DWDVH G TQY FYN ++VL+IS+HRYE FWP LRE +YD+IG GRG+NINIPLNKT MT+ DYL+IF+S+I+PIAYE+NPE+V +S+GFD+A+G PEG M + PAC+ HMTH+L LA G++VV+LEGGY +ESL++ V L L G L+ P S++ TI + + L FW+ L + P+ R P ++W K P E NP
Sbjct: 1119 KFGKGTGICFDERMEQHRHEWFLDEQECPERVARPLKLMEDQGLISRCTRVPARHATDEELLKVHSKDYIELVKSSAKMGKDELYSLSGNYDGVFFNSHTWEASSLAAGSVTELASQIANGKVANGLALVRPPGHHAMYDEACGYCIFGNVSIAVASLLDSLPLSLYNPIPSKVRPLTSTTSPKNSLRSPRFKRILIIDWDVHQGQGTQYNFYNDNRVLFISMHRYECQKFWPMLREGDYDFIGDGIGRGFNINIPLNKTGMTDGDYLAIFYSLIMPIAYEFNPEIVFVSSGFDAAVGDPEGKMWISPACYGHMTHQLRTLADGKLVVVLEGGYFIESLEEGCVQVLKALLGDYIAPLQNLSPPSKSIRCTISSSIIALREFWQCLGLVELSLCSTRPDISR-FPPNSWPLVKKVVWP-EKNP 1539 HSP 3 Score: 249.98 bits (637), Expect = 1.353e-63 Identity = 133/421 (31.59%), Postives = 223/421 (52.97%), Query Frame = 2
Query: 1475 ELRTKNAFNNYPNKTCF-----------VYDCRMENHMNERSI-HPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKY--------------------------SESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINF-PINKSGIEAIRKTLEYQKPYWKCLKFYE-PLVVTYTEIS 2617
E++ K + P +C +D RME H +E + E P R + + D L+SRC ++ +R A+ +E+ +HS +Y+E + + + + ++ ++ N H++ ++ L+ G + + ++ + + NG A++RPPGHHA + G+C F NV+IA L S K+ILI+DWDVH G GTQ+ F+ + VL+IS+HRY+ F+P +G +G GFN+NI NK + D +Y++ F +++MPI++EFNP++V VS+GFDAA GDP G + ++P C+G+MT L +LA+GK+++ LEGGY + + + + +LLG + N P +KS I ++ + +W+CL E L T +IS
Sbjct: 1099 EMKAKPQTTSAPQTSCLDEAKFGKGTGICFDERMEQHRHEWFLDEQECPERVARPLKLMEDQGLISRCTRVPARHATDEELLKVHSKDYIELVKSSAKMGKDELYSLSGNYDGVFFNSHTWEASSLAAGSVTELASQIANGKVANGLALVRPPGHHAMYDEACGYCIFGNVSIAVASLLDSLPLSLYNPIPSKVRPLTSTTSPKNSLRSPRFKRILIIDWDVHQGQGTQYNFYNDNRVLFISMHRYECQKFWPMLREGDYDFIGDGIGRGFNINIPLNKTGMTDGDYLAIFYSLIMPIAYEFNPEIVFVSSGFDAAVGDPEGKMWISPACYGHMTHQLRTLADGKLVVVLEGGYFIESLEEGCVQVLKALLGDYIAPLQNLSPPSKSIRCTISSSIIALREFWQCLGLVELSLCSTRPDIS 1519
BLAST of Histone deacetylase,putative vs. Ensembl Cavefish
Match: hdac6 (histone deacetylase 6 [Source:ZFIN;Acc:ZDB-GENE-030131-3232]) HSP 1 Score: 734.561 bits (1895), Expect = 0.000e+0 Identity = 411/1084 (37.92%), Postives = 587/1084 (54.15%), Query Frame = 2
Query: 230 NIELRIN-FPNKTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGS-MDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSV---NVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKENDQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMNE-RSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLG-YPTNQIINFPINKSGIEAIRKTLEYQKPYWKCLKFYEPLVVTYTEISP-----------NQTNPAALDNIVQIDTNTLAESVRQLGIVEVTFQTEQSIEETLSQPRNDTFITEPNSSNPIIHLPPIVSSDNAVEVPATTSINSTTHATQNISANFLSVDQSSGATPVSANVSRVIN------EGNSVGLVLQDIMNLSGVSNSDIHHFLGLTSN--DPLPERVYAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQVFCGRFVQAHMMQHFQNTRHAIVLSFVDLSSWCYECDSYVHNECLNHAKREAHIAKFG 3403
NI+LR T VY E H +WD + E P+R+ E + + LL C++++ + E I H++ ++ + TQ MT ++K +S +D V+ +T + ++ GS ++++ V+ +NGF + RPPGHHA +G+C+FNN+ +AA+YAQ + Q++LIVDWDVHHG QY F + VLY S+HRYEDG+FWP L ES+ +G+ G GYNIN+P NKT M + DY++ F ++LP+AYE+ P+LVL++AGFDS +G P+G M P CF+ +TH LM LA+GR+V+ LEGGY +++ + +L +L G P L P +S +I + L+ FW SL + EP P SS ++ +E + LR+ T VYD RM H N S HPE P+R IF + + RC+++ +RLA+++E+ L H ++ ++ + Q P H +E+NSIYI+Q SY SALL+ G N + + + NG AI+RPPGHHAE + GFCFFN A+ A YA + + S ++LI+DWDVHHGNGTQH F + +VLYISLHRY++GLFFP S D + VG G+NVNI WNK + D EY++AF NIVMPI+ EF P+LV+VSAGFDAARGDPLG VTPE + ++T L SLA G+V++ LEGGYNLN IS+ M+ C S LLG P P + S I L PYW+ L+ P + + SP ++ +P + V Q + ++E L+Q + ++ S+N P+ + V+ + S + + + V +S A P+ S I E ++V + QD L G L D + +Y V PL WC HL V+ P IDV C C + ENW+CL CY+V CGRFV+ HM+ H Q + H +VLSF DLS WCY C+SYVHN+ L+ K AH+AKFG
Sbjct: 65 NIDLRCKPKATGTGLVYSEAFTHHRCLWDTSHPECPERVIAVVELMKKEGLLSRCVQVETRAASEEEISLVHTKEYIDRMRSTQKMTEEEMKLVSDGYDSVYLHPDTFSCACLAVGSVLQLVDKVMTSELRNGFSVSRPPGHHAQTELMNGYCMFNNLAVAARYAQKQHGVQRVLIVDWDVHHGQGIQYIFQDDPNVLYFSVHRYEDGSFWPHLPESDSSAVGSGLGEGYNINLPWNKTGMQDGDYVAAFQRLLLPVAYEFQPQLVLVAAGFDSVVGDPQGGEMSASPQCFSVLTHMLMGLAQGRIVLALEGGYNLQATAEGACASLRSLLGDPCPHLPCPGSPSESALNSISKTVSDLYPFWTSLQILEGGALSEAEPLP------------SSVCAEMNLESS----------------LRS----------TGLVYDQRMMEHHNMWDSDHPERPQRIFRIFSRHEELGFVDRCQRIPARLATEEELALCHGLEHIATIKSTEQMKPRDLHRLGDEYNSIYISQESYKSALLAAGSCFNSAQAILTGQVRNGVAIVRPPGHHAERDKACGFCFFNTAALTARYAQS-ITHSALRVLILDWDVHHGNGTQHIFEEDDSVLYISLHRYEDGLFFPSSEDANYDKVGQGKGAGYNVNIPWNKATMGDPEYLAAFHNIVMPIAREFAPELVLVSAGFDAARGDPLGRYQVTPEGYAHLTHQLLSLAAGRVLVILEGGYNLNSISESMAMCTSMLLGDAPPMLPDLPPPHASAAVTINNVLRAHAPYWRSLRIQIPESLRMSLPSPQPKTKRSSTGRSKKSPRQFTPAQSPSQQQQSSPVITSPASPAAAQEDSGLDE-LTQGLHSLDLSSSTSANSSPTSIPVGGARPKVKPSPQKDVTSA------LEESPVKVIESDRAEPIVKAESTPIKEEKQPAEADAVAMGDQDSGVLEGACGFTQKSVFELVCGAVDMGGDTMYVVDPLAWCPHLESVRPLPVGG-IDVFRPCEECGADSENWVCLCCYKVLCGRFVKEHMVTHGQVSGHPMVLSFADLSVWCYPCESYVHNKVLHEIKNAAHVAKFG 1101
BLAST of Histone deacetylase,putative vs. Ensembl Cavefish
Match: hdac6 (histone deacetylase 6 [Source:ZFIN;Acc:ZDB-GENE-030131-3232]) HSP 1 Score: 716.072 bits (1847), Expect = 0.000e+0 Identity = 404/1049 (38.51%), Postives = 576/1049 (54.91%), Query Frame = 2
Query: 326 ERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSV---NVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKENDQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMNE-RSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLG-YPTNQIINFPINKSGIEAIRKTLEYQKPYWKCLKFYEPLVVTYTEISPNQTNPAALDNIVQIDTNTLAESVRQL----------------GIVEVTFQTEQSIEETLSQPRNDTFITEP-NSSNPIIHLPPIVSSDNAVEVPATTSINSTTHATQNISANFLSV-DQSSGATPVSANVSRVINEGNSVGLVLQDIMNLSGVSNSDIHHFLGLTSNDPLPERVYAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQVFCGRFVQAHMMQHFQNTRHAIVLSFVDLSSWCYECDSYVHNECLNHAKREAHIAKFG 3403
E P+R+ E + + LL C++++ + E I H++ ++ + TQ MT ++K +S +D V+ +T + ++ GS ++++ V+ +NGF + RPPGHHA +G+C+FNN+ +AA+YAQ + Q++LIVDWDVHHG QY F + VLY S+HRYEDG+FWP L ES+ +G+ G GYNIN+P NKT M + DY++ F ++LP+AYE+ P+LVL++AGFDS +G P+G M P CF+ +TH LM LA+GR+V+ LEGGY +++ + +L +L G P L P +S +I + L+ FW SL + EP P SS ++ +E + LR+ T VYD RM H N S HPE P+R IF + + RC+++ +RLA+++E+ L H ++ ++ + Q P H +E+NSIYI+Q SY SALL+ G N + + + NG AI+RPPGHHAE + GFCFFN A+ A YA + + S ++LI+DWDVHHGNGTQH F + +VLYISLHRY++GLFFP S D + VG G+NVNI WNK + D EY++AF NIVMPI+ EF P+LV+VSAGFDAARGDPLG VTPE + ++T L SLA G+V++ LEGGYNLN IS+ M+ C S LLG P P + S I L PYW+ L+ P + + SP + T +S RQ G+ E+T Q S++ + S N + + P + P + P +A+E I S ++ A+ +++ DQ SG + EG + G + + L V +D +Y V PL WC HL V+ P IDV C C + ENW+CL CY+V CGRFV+ HM+ H Q + H +VLSF DLS WCY C+SYVHN+ L+ K AH+AKFG
Sbjct: 86 ECPERVIAVVELMKKEGLLSRCVQVETRAASEEEISLVHTKEYIDRMRSTQKMTEEEMKLVSDGYDSVYLHPDTFSCACLAVGSVLQLVDKVMTSELRNGFSVSRPPGHHAQTELMNGYCMFNNLAVAARYAQKQHGVQRVLIVDWDVHHGQGIQYIFQDDPNVLYFSVHRYEDGSFWPHLPESDSSAVGSGLGEGYNINLPWNKTGMQDGDYVAAFQRLLLPVAYEFQPQLVLVAAGFDSVVGDPQG-MSASPQCFSVLTHMLMGLAQGRIVLALEGGYNLQATAEGACASLRSLLGDPCPHLPCPGSPSESALNSISKTVSDLYPFWTSLQILEGGALSEAEPLP------------SSVCAEMNLESS----------------LRS----------TGLVYDQRMMEHHNMWDSDHPERPQRIFRIFSRHEELGFVDRCQRIPARLATEEELALCHGLEHIATIKSTEQMKPRDLHRLGDEYNSIYISQESYKSALLAAGSCFNSAQAILTGQVRNGVAIVRPPGHHAERDKACGFCFFNTAALTARYAQS-ITHSALRVLILDWDVHHGNGTQHIFEEDDSVLYISLHRYEDGLFFPSSEDANYDKVGQGKGAGYNVNIPWNKATMGDPEYLAAFHNIVMPIAREFAPELVLVSAGFDAARGDPLGRYQVTPEGYAHLTHQLLSLAAGRVLVILEGGYNLNSISESMAMCTSMLLGDAPPMLPDLPPPHASAAVTINNVLRAHAPYWRSLRIQIPESLRMSLPSPQPKTKRS-------STGRSKKSPRQFTPAQSPSQQQQSSPDSGLDELT-QGLHSLDLSSSTSANSSPTSIPVGGARPKVKPSPQKDVTSALEESPVKVIESDRSFSEPAEADAVAMGDQDSG-----------VLEG-ACGFTQKSVFEL--VCGADT---------------MYVVDPLAWCPHLESVRPLPVGG-IDVFRPCEECGADSENWVCLCCYKVLCGRFVKEHMVTHGQVSGHPMVLSFADLSVWCYPCESYVHNKVLHEIKNAAHVAKFG 1056 HSP 2 Score: 315.464 bits (807), Expect = 3.349e-90 Identity = 158/389 (40.62%), Postives = 234/389 (60.15%), Query Frame = 2
Query: 263 TAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQ-LNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHE-----PYPEYLRHLPESTWNSSKVPK 1411
T VYD++M+ H NMWD+ + ERP R+ + E ++ C RI A+ E + H H+ I+ T+ M L L +++ ++ + ++ ++AGS +A+L + +NG ++RPPGHHA +A GFC FN + A+YAQ + +S ++LI+DWDVHHGN TQ+ F VLYIS+HRYEDG F+P ++NYD +G +G GYN+NIP NK M + +YL+ FH+I++PIA E+ PELVL+SAGFD+A G P G V P +AH+TH+L+ LA GRV+V+LEGGY + S+ +S+ + + L G APP L P S TI N L+ +W+SL + + ++ P P+ R ST S K P+
Sbjct: 447 TGLVYDQRMMEHHNMWDSDHPERPQRIFRIFSRHEELGFVDRCQRIPARLATEEELALCHGLEHIATIKSTEQMKPRDLHRLGDEYNSIYISQESYKSALLAAGSCFNSAQAILTGQVRNGVAIVRPPGHHAERDKACGFCFFNTAALTARYAQSITHSALRVLILDWDVHHGNGTQHIFEEDDSVLYISLHRYEDGLFFPSSEDANYDKVGQGKGAGYNVNIPWNKATMGDPEYLAAFHNIVMPIAREFAPELVLVSAGFDAARGDPLGRYQVTPEGYAHLTHQLLSLAAGRVLVILEGGYNLNSISESMAMCTSMLLGDAPPMLPDLPPPHASAAVTINNVLRAHAPYWRSLRIQIPESLRMSLPSPQPKTKR---SSTGRSKKSPR 832 HSP 3 Score: 296.975 bits (759), Expect = 9.161e-84 Identity = 137/352 (38.92%), Postives = 224/352 (63.64%), Query Frame = 2
Query: 1571 HPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQI-INFPINKSGIEAIRKTLEYQKPYWKCLKFYEPLVVTYTEISPN 2623
HPE P R + E ++ LLSRC Q+E+R AS++EI L+H+ Y++ + + + + L + ++S+Y++ ++ A L+ G +L ++D+V + NGF++ RPPGHHA+ G+C FNN+A+AA YA ++ ++++LIVDWDVHHG G Q+ F + NVLY S+HRY++G F+P + SAVG EG+N+N+ WNK ++D +Y++AF +++P+++EF P LV+V+AGFD+ GDP G++ +P+CF +T ML LA G+++LALEGGYNL ++ + SLLG P + ++S + +I KT+ P+W L+ E ++ E P+
Sbjct: 84 HPECPERVIAVVELMKKEGLLSRCVQVETRAASEEEISLVHTKEYIDRMRSTQKMTEEEMKLVSDGYDSVYLHPDTFSCACLAVGSVLQLVDKVMTSELRNGFSVSRPPGHHAQTELMNGYCMFNNLAVAARYAQKQHG--VQRVLIVDWDVHHGQGIQYIFQDDPNVLYFSVHRYEDGSFWPHLPESDSSAVGSGLGEGYNINLPWNKTGMQDGDYVAAFQRLLLPVAYEFQPQLVLVAAGFDSVVGDPQ-GMSASPQCFSVLTHMLMGLAQGRIVLALEGGYNLQATAEGACASLRSLLGDPCPHLPCPGSPSESALNSISKTVSDLYPFWTSLQILEGGALSEAEPLPS 432
BLAST of Histone deacetylase,putative vs. Ensembl Cavefish
Match: hdac10 (histone deacetylase 10 [Source:NCBI gene;Acc:103023019]) HSP 1 Score: 333.569 bits (854), Expect = 1.878e-100 Identity = 157/355 (44.23%), Postives = 224/355 (63.10%), Query Frame = 2
Query: 263 TAFVYDEQMLLHSNMWDN--LYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSL 1321
TA +YDE+M + +WD+ E P+RL YE + L + C+ + +E E I HS+ +++ ++ T +M+ +LK + Q V+F N + ++ G++++++ +V+ + +NG L+RPPGHH+ S A+GFC+FNNV IAA YA+ +Y+ ++LIVDWDVHHG QY F VLY S HRYE +FWP L ES+Y+ +G +G G+NIN+P NK MTNSDYLS+F ++LP AYE++PELVL+SAGFDSAIG PEG M P F H+TH LM LA+G++ V+LEGGY + SL SV T+ TL G P L PC S E++ N +W L
Sbjct: 4 TALIYDEEMSRYQLLWDDPVCAIEVPERLTRSYEAVKSAGLEKRCVPVSVREGTEEEILLYHSKEYLEQVKQTPSMSVEELKTFTQQFGDVYFHPNIYNCAKLAIGASLQLVDSVMKGKVRNGMALVRPPGHHSQRSAANGFCVFNNVAIAALYAKKHYNLNRVLIVDWDVHHGQGVQYCFEEDPSVLYFSWHRYEHKSFWPNLDESDYNTVGKGKGTGFNINVPWNKVGMTNSDYLSVFFHVLLPAAYEFDPELVLVSAGFDSAIGDPEGHMCATPEIFGHLTHLLMSLAKGKLCVVLEGGYNLTSLTQSVCQTMHTLLGDPTPLLSGIGSPCHSALESVVNVRAVHRKYWNFL 358 HSP 2 Score: 266.544 bits (680), Expect = 2.093e-76 Identity = 137/360 (38.06%), Postives = 210/360 (58.33%), Query Frame = 2
Query: 1517 TCFVYDCRMENHM---NERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQI--INFPINKSGIEAIRKTLEYQKPYWKCLKF 2581
T +YD M + ++ E P R +E ++ L RC + R +++EI L HS Y+E + S F ++F +Y + + Y A L+ G L ++D V + NG A++RPPGHH++ + GFC FNNVAIAA YA Y+ + ++LIVDWDVHHG G Q+ F + +VLY S HRY++ F+P + + VG GFN+N+ WNK + +S+Y+S F ++++P ++EF+P+LV+VSAGFD+A GDP G + TPE FG++T +L SLA GK+ + LEGGYNL ++ + + +LLG PT + I P + S +E++ + YW LK+
Sbjct: 4 TALIYDEEMSRYQLLWDDPVCAIEVPERLTRSYEAVKSAGLEKRCVPVSVREGTEEEILLYHSKEYLEQVKQTPSMSVEELKTFTQQFGDVYFHPNIYNCAKLAIGASLQLVDSVMKGKVRNGMALVRPPGHHSQRSAANGFCVFNNVAIAALYAKKHYN--LNRVLIVDWDVHHGQGVQYCFEEDPSVLYFSWHRYEHKSFWPNLDESDYNTVGKGKGTGFNINVPWNKVGMTNSDYLSVFFHVLLPAAYEFDPELVLVSAGFDSAIGDPEGHMCATPEIFGHLTHLLMSLAKGKLCVVLEGGYNLTSLTQSVCQTMHTLLGDPTPLLSGIGSPCH-SALESVVNVRAVHRKYWNFLKY 360
BLAST of Histone deacetylase,putative vs. Ensembl Cavefish
Match: hdac10 (histone deacetylase 10 [Source:NCBI gene;Acc:103023019]) HSP 1 Score: 333.183 bits (853), Expect = 8.136e-100 Identity = 157/355 (44.23%), Postives = 224/355 (63.10%), Query Frame = 2
Query: 263 TAFVYDEQMLLHSNMWDN--LYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSL 1321
TA +YDE+M + +WD+ E P+RL YE + L + C+ + +E E I HS+ +++ ++ T +M+ +LK + Q V+F N + ++ G++++++ +V+ + +NG L+RPPGHH+ S A+GFC+FNNV IAA YA+ +Y+ ++LIVDWDVHHG QY F VLY S HRYE +FWP L ES+Y+ +G +G G+NIN+P NK MTNSDYLS+F ++LP AYE++PELVL+SAGFDSAIG PEG M P F H+TH LM LA+G++ V+LEGGY + SL SV T+ TL G P L PC S E++ N +W L
Sbjct: 4 TALIYDEEMSRYQLLWDDPVCAIEVPERLTRSYEAVKSAGLEKRCVPVSVREGTEEEILLYHSKEYLEQVKQTPSMSVEELKTFTQQFGDVYFHPNIYNCAKLAIGASLQLVDSVMKGKVRNGMALVRPPGHHSQRSAANGFCVFNNVAIAALYAKKHYNLNRVLIVDWDVHHGQGVQYCFEEDPSVLYFSWHRYEHKSFWPNLDESDYNTVGKGKGTGFNINVPWNKVGMTNSDYLSVFFHVLLPAAYEFDPELVLVSAGFDSAIGDPEGHMCATPEIFGHLTHLLMSLAKGKLCVVLEGGYNLTSLTQSVCQTMHTLLGDPTPLLSGIGSPCHSALESVVNVRAVHRKYWNFL 358 HSP 2 Score: 265.774 bits (678), Expect = 1.230e-75 Identity = 137/360 (38.06%), Postives = 210/360 (58.33%), Query Frame = 2
Query: 1517 TCFVYDCRMENHM---NERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQI--INFPINKSGIEAIRKTLEYQKPYWKCLKF 2581
T +YD M + ++ E P R +E ++ L RC + R +++EI L HS Y+E + S F ++F +Y + + Y A L+ G L ++D V + NG A++RPPGHH++ + GFC FNNVAIAA YA Y+ + ++LIVDWDVHHG G Q+ F + +VLY S HRY++ F+P + + VG GFN+N+ WNK + +S+Y+S F ++++P ++EF+P+LV+VSAGFD+A GDP G + TPE FG++T +L SLA GK+ + LEGGYNL ++ + + +LLG PT + I P + S +E++ + YW LK+
Sbjct: 4 TALIYDEEMSRYQLLWDDPVCAIEVPERLTRSYEAVKSAGLEKRCVPVSVREGTEEEILLYHSKEYLEQVKQTPSMSVEELKTFTQQFGDVYFHPNIYNCAKLAIGASLQLVDSVMKGKVRNGMALVRPPGHHSQRSAANGFCVFNNVAIAALYAKKHYN--LNRVLIVDWDVHHGQGVQYCFEEDPSVLYFSWHRYEHKSFWPNLDESDYNTVGKGKGTGFNINVPWNKVGMTNSDYLSVFFHVLLPAAYEFDPELVLVSAGFDSAIGDPEGHMCATPEIFGHLTHLLMSLAKGKLCVVLEGGYNLTSLTQSVCQTMHTLLGDPTPLLSGIGSPCH-SALESVVNVRAVHRKYWNFLKY 360 HSP 3 Score: 55.0694 bits (131), Expect = 4.679e-7 Identity = 38/136 (27.94%), Postives = 63/136 (46.32%), Query Frame = 2
Query: 914 YNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSL 1321
Y++ + L+K + + + ++LP+AYE++P+LVL S + P +A ++ L LA+GR + LL+G KD V T ++L+G P L P D E I+ + L W L
Sbjct: 548 YHVPVCLSKAGHSRASVMQALIGLLLPLAYEFSPDLVLQVLTSSSGLEMP---------VWAQVSSLLQGLAQGRTLALLQG-----CDKDMVGATCSSLSGSPAPILGPLGHPVDKDVEFIEKQRQRLEKKWGLL 669
BLAST of Histone deacetylase,putative vs. Ensembl Cavefish
Match: hdac7a (histone deacetylase 7a [Source:ZFIN;Acc:ZDB-GENE-150129-1]) HSP 1 Score: 305.449 bits (781), Expect = 7.779e-88 Identity = 162/379 (42.74%), Postives = 231/379 (60.95%), Query Frame = 2
Query: 1517 TCFVYDCRMENHM---NERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEF-------------NSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWN---KRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARG--DPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLG----YPTNQIINFPINKSGIEAIRKTLEYQKPYWKCLK 2578
T VYD +M H + S HPE R Q I+ L++ L +C+ + R A+ +E+ + Y++S+ IC P L + F ++I+ H+ ++ ++ G + + V +NGFA++RPPGHHA+ + P+GFCFFN+VAIAA K S + KILIVDWDVHHGNGTQ F+ + +VLYISLHRYDNG FFPGS G P+ VG EGFNVN+AW + P+ D+EY++AF +VMPI+ EF+PD+V+VS+GFDAA G PLGG VT +CFG +T+ L LA G+V+LALEGG++L I D CVS+LLG +P ++ P N + + ++++ L+ Q YW +K
Sbjct: 483 TGLVYDSQMLKHQCTCGDNSTHPEHAGRIQSIWSRLQERGLRVQCESIRGRKATLEELSSV----YIKSV--ICVTLPPTGILSQRMFVMLPCGGVGVIDHDTIWNEMHTSTASRMAAGSVTELAFRVAKGELKNGFAVVRPPGHHADPSNPMGFCFFNSVAIAAKQLQQKLS--VTKILIVDWDVHHGNGTQEIFYNDPSVLYISLHRYDNGNFFPGS--GGPTEVGSGAGEGFNVNVAWTGGLEPPMGDAEYLAAFRTVVMPIAREFSPDVVLVSSGFDAAEGHPAPLGGYKVTAKCFGFLTRQLMVLAGGRVVLALEGGHDLTAICDASEACVSALLGVEDPFPEEVLLQKP-NDNAVLSLQRVLQIQSQYWSSVK 850 HSP 2 Score: 234.572 bits (597), Expect = 1.562e-63 Identity = 136/374 (36.36%), Postives = 205/374 (54.81%), Query Frame = 2
Query: 263 TAFVYDEQMLLHS-NMWDN-LYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQL-IEDTQTMTAIQLKELSS------QHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLN---KTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIG--CPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEK--FDEPCDSVKETIQNCLKFLHFFWKSLSVNVA 1336
T VYD QML H DN + E R++ + + E L C I+ ++ E + + +S + + + T ++ L HD ++ + +T AS ++AGS E+ V KNGF ++RPPGHHA S GFC FN+V IAAK Q S KILIVDWDVHHGN TQ FYN VLYIS+HRY++GNF+P +G+ G G+N+N+ + M +++YL+ F ++++PIA E++P++VL+S+GFD+A G P G V CF +T +LM LA GRVV+ LEGG+ + ++ D+ ++ L G P E+ +P D+ ++Q L+ +W S+ V
Sbjct: 483 TGLVYDSQMLKHQCTCGDNSTHPEHAGRIQSIWSRLQERGLRVQCESIRGRKATLEELSSVYIKSVICVTLPPTGILSQRMFVMLPCGGVGVIDHDTIWNEMHTSTASRMAAGSVTELAFRVAKGELKNGFAVVRPPGHHADPSNPMGFCFFNSVAIAAKQLQQKLSVTKILIVDWDVHHGNGTQEIFYNDPSVLYISLHRYDNGNFFPG--SGGPTEVGSGAGEGFNVNVAWTGGLEPPMGDAEYLAAFRTVVMPIAREFSPDVVLVSSGFDAAEGHPAPLGGYKVTAKCFGFLTRQLMVLAGGRVVLALEGGHDLTAICDASEACVSALLGVEDPFPEEVLLQKPNDNAVLSLQRVLQIQSQYWSSVKAMVG 854
BLAST of Histone deacetylase,putative vs. Ensembl Sea Lamprey
Match: hdac6 (histone deacetylase 6 [Source:ZFIN;Acc:ZDB-GENE-030131-3232]) HSP 1 Score: 586.26 bits (1510), Expect = 0.000e+0 Identity = 308/781 (39.44%), Postives = 447/781 (57.23%), Query Frame = 2
Query: 263 TAFVYDEQMLLHSNMWDNLYFERPDRLRVCYE--GICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEP-CDSVKETIQNCLKFLHFFWKSLSVNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKENDQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMNE-RSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINFPINKSGIEAI-RKTLEYQKPYWKCLKFYEP 2590
T V+D +M L S W+ + P LR E + NL C+ + + E + + HSQ ++++++ T M+ + K LS D V+ + + ++ GS +++++ VL +NGF L+RPPGHHA A+G+CIFNNV IAA+YA + Q++LIVDWDVHHG QY F + +VLY S+HR+E G FWP L E + +G +G+NIN+P ++T M+++DY++ F I++P+AY+++P+LVL+SAG+D+A+G P+G M V P CF +TH LM LA GR+ + LEGGY +E V TL L G + C E I + K L KS SV+ D+ E K + E +P E + E R T VYD RM +H N HPE P R ++F D L+ RC + +RLA+++E+ HS +V ++ H ++NS+Y++ S+ SA L+ G L++++ + NG AIIRPPGHHAE + GFC FN VA+AA +A + I+ +LIVDWDVHHGNGTQH F + +VLY+SLHRYD G FFP S D + VG +GFNVN+ W +R++EY++AF + V+PI++EF+P+LV+VSAGFDAA+GDPLG VTP+C+ +MT ML LANG+V+L LEGGYNL I++CM+ C +LLG T + ++G E + L P W L+ P
Sbjct: 13 TGLVFDARMELVSCPWERCF---PSSLRFHSEPQTLVMFNLKYFCVSRKPRMASVEELMFCHSQEYIRMMQSTAEMSDQERKSLSDTFDSVYLHKGSYDGALLAVGSVLQLVERVLTGDLRNGFALVRPPGHHAQRDLANGYCIFNNVAIAAQYALSQHQLQRVLIVDWDVHHGQGIQYTFQDDPRVLYFSVHRHEGGAFWPHLSEGDVTAVGRGIAKGFNINLPWSRTGMSDADYVTAFQQILMPVAYQFSPQLVLVSAGYDAALGDPKGEMCVSPPCFGLLTHMLMSLANGRLCLALEGGYNLEVTAAGVCATLHALLGDPVTSTGGSRQAKCSCSSERIDSSFKCLA---KSTSVSENDDKE----------------GKEIETDREKDPASTTEIGVMTTVTMETRI----------TGLVYDKRMRDHHNMWDRFHPEQPDRISVMFSRHEDLGLVGRCHMVTARLATEEELLTCHSVRHVNAMRETTSMKARDLHRCSADYNSVYLSPSSFDSACLAAGAALSLVEAAMCGQVSNGVAIIRPPGHHAESDVACGFCLFNTVALAAKHAQSLARRQIR-VLIVDWDVHHGNGTQHIFEDDPSVLYVSLHRYDGGRFFPCSEDANVDRVGTGPGKGFNVNVPWPGPYMRNAEYLAAFTSTVLPIAYEFDPELVLVSAGFDAAQGDPLGLCMVTPDCYAHMTHMLLGLANGRVLLFLEGGYNLTTIAECMAMCTRTLLGDSTLALGPLEPPQAGAERVLTSVLHTHSPLWHNLRIPAP 760 HSP 2 Score: 294.664 bits (753), Expect = 3.029e-83 Identity = 144/388 (37.11%), Postives = 227/388 (58.51%), Query Frame = 2
Query: 188 EDLPAAQSNHGLYDNIELRINFPNKTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQ-LNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHE 1348
E PA+ + G+ + + T VYD++M H NMWD + E+PDR+ V + + L+ C + A+ E + HS HV + +T +M A L S+ ++ V+ ++ ++ ++AG+ + +++A + + NG +IRPPGHHA A GFC+FN V +AAK+AQ L ++LIVDWDVHHGN TQ+ F + VLY+S+HRY+ G F+P ++N D +G G+G+N+N+P M N++YL+ F S +LPIAYE++PELVL+SAGFD+A G P G V P C+AHMTH L+ LA GRV++ LEGGY + ++ + + + TL G + L + P + + + L W +L + ++ +
Sbjct: 380 EKDPASTTEIGVMTTVTMETRI---TGLVYDKRMRDHHNMWDRFHPEQPDRISVMFSRHEDLGLVGRCHMVTARLATEEELLTCHSVRHVNAMRETTSMKARDLHRCSADYNSVYLSPSSFDSACLAAGAALSLVEAAMCGQVSNGVAIIRPPGHHAESDVACGFCLFNTVALAAKHAQSLARRQIRVLIVDWDVHHGNGTQHIFEDDPSVLYVSLHRYDGGRFFPCSEDANVDRVGTGPGKGFNVNVPWPGPYMRNAEYLAAFTSTVLPIAYEFDPELVLVSAGFDAAQGDPLGLCMVTPDCYAHMTHMLLGLANGRVLLFLEGGYNLTTIAECMAMCTRTLLGDSTLALGPLEPPQAGAERVLTSVLHTHSPLWHNLRIPAPEDGQ 764 HSP 3 Score: 137.117 bits (344), Expect = 7.400e-33 Identity = 62/133 (46.62%), Postives = 84/133 (63.16%), Query Frame = 2
Query: 3017 SGVSNSDIHHFLGLTSNDPLPERVYAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQVFCGRFVQAHMMQHFQNTRHAIVLSFVDLSSWCYECDSYVHNECLNHAKREAHIAKFGVPQP 3415
SG+ D+ L S P YAV+PL WC HL+ V P +D ++ C C + ENWLCL CY+ +CGR+V+ HM+QH + + HA+VLSF DLS+WCY CDSYVH+E L+ +KR A+ +KF P
Sbjct: 1003 SGIHEDDVG--LAEASGWTPPSLCYAVKPLSWCPHLDAVTAIP-GGAVDPSSPCVDCGDSSENWLCLVCYEAYCGRYVRGHMLQHSEKSGHALVLSFADLSAWCYSCDSYVHHEALHESKRAAYRSKFDEEMP 1132
BLAST of Histone deacetylase,putative vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005422.1 (pep scaffold:Pmarinus_7.0:GL501185:343872:431549:1 gene:ENSPMAG00000004812.1 transcript:ENSPMAT00000005422.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 291.197 bits (744), Expect = 1.273e-82 Identity = 153/389 (39.33%), Postives = 234/389 (60.15%), Query Frame = 2
Query: 1517 TCFVYDCRMENHM---NERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYV----------------ESLGNICQESPTIYHLFE-----EEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKR---PVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARG--DPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYP----TNQIINFPINKSGIEAIRKTLEYQKPYWKCLKFY 2584
T VYD M H + HPE R Q I+ L++ LL +C+++ R A+ +EI ++HS + + LG++ Q+ ++ L + ++++ HS +A ++ G + + +V S +NGFA++RPPGHHAE + +GFCFFN+VAIAA K++ ++KILI+DWDVHHGNGTQ F+ + ++LY+SLHRYD G FFPGS G+ VG GFNVNIAW P+ D+EY++AF +V+PI++EF+PD+V+VS+GFDAA G PLGG V+ +CFG++T+ L LA G+V++ALEGG++L I D C+S+LLG + I+ N + + ++ K ++ Q YWK + +
Sbjct: 609 TGVVYDSLMLKHQCSCGNNNNHPEHAGRIQSIWSRLQERGLLRKCERVRGRKATLEEIEMVHSEQHALLYSTNPLNRQKLDSKKLLGSLSQK---MFGLLPCGGLGVDSDTVWNELHSASAARMAAGCVSELACKVASGELKNGFAVVRPPGHHAEESAAMGFCFFNSVAIAAKLLQQKFN--VRKILIIDWDVHHGNGTQQAFYGDASILYLSLHRYDGGNFFPGS--GASEEVGTGAGIGFNVNIAWTGGLDPPMGDAEYLAAFRTVVLPIANEFSPDVVLVSSGFDAAEGHPPPLGGYKVSAKCFGHLTRQLMGLAGGRVVMALEGGHDLAAICDGSESCISALLGNELEPLSMDILQQQPNPNAVVSLEKVIDIQSKYWKSVAHF 990 HSP 2 Score: 237.269 bits (604), Expect = 1.497e-64 Identity = 135/385 (35.06%), Postives = 210/385 (54.55%), Query Frame = 2
Query: 263 TAFVYDEQMLLH--SNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHV----------QLIEDTQTMTAIQLK--------ELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKT---NMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPE--GSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKF------DEPCDSVKETIQNCLKFLHFFWKSLS 1324
T VYD ML H S +N + E R++ + + E LL C R++ ++ E I HS+ H Q ++ + + ++ K L D V+ + ++ A+ ++AG E+ V KNGF ++RPPGHHA ES A GFC FN+V IAAK Q ++ +KILI+DWDVHHGN TQ FY + +LY+S+HRY+ GNF+P S + +G G G+N+NI M +++YL+ F +++LPIA E++P++VL+S+GFD+A G P G V CF H+T +LM LA GRVV+ LEGG+ + ++ D ++ L G +LE +P + +++ + +WKS++
Sbjct: 609 TGVVYDSLMLKHQCSCGNNNNHPEHAGRIQSIWSRLQERGLLRKCERVRGRKATLEEIEMVHSEQHALLYSTNPLNRQKLDSKKLLGSLSQKMFGLLPCGGLGVDSDTVWNELHSASAARMAAGCVSELACKVASGELKNGFAVVRPPGHHAEESAAMGFCFFNSVAIAAKLLQQKFNVRKILIIDWDVHHGNGTQQAFYGDASILYLSLHRYDGGNFFPGSGAS--EEVGTGAGIGFNVNIAWTGGLDPPMGDAEYLAAFRTVVLPIANEFSPDVVLVSSGFDAAEGHPPPLGGYKVSAKCFGHLTRQLMGLAGGRVVMALEGGHDLAAICDGSESCISALLGN---ELEPLSMDILQQQPNPNAVVSLEKVIDIQSKYWKSVA 988
BLAST of Histone deacetylase,putative vs. Ensembl Sea Lamprey
Match: hdac4 (histone deacetylase 4 [Source:ZFIN;Acc:ZDB-GENE-061013-95]) HSP 1 Score: 223.787 bits (569), Expect = 1.312e-60 Identity = 129/310 (41.61%), Postives = 176/310 (56.77%), Query Frame = 2
Query: 1508 PNKTCF----VYDCRMENHM---NERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLG------------NICQESPTIYHLFE-----EEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKR---PVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDP--LGGLTVTPEC 2350
PN+ F VYD M H + S HPE R I+ L+ LLS+C+ + R AS +I +HS +V G + PT L + ++ + + HS +A ++ G + + V S + +NGFAI+RPPGHHAE + +GFC FN+VAIAA L + +++ILIVD DVHHGNGTQ F+ + VLY+SLHRYDNG FFPGS G+ S VG EGF VN++W P+ D++Y++AF +VMPI+ EF PD+V+VSAGFDA G P LGG +T C
Sbjct: 600 PNRPSFSTGVVYDTLMVRHQCSCGDDSNHPEHAGRIMAIWARLQQTGLLSKCEVIAGRKASLKDIQTVHSELHVLRYGTNPLNRQKLDTQGLLDAQPTQLMLLRCGGVGVDSDTYWSDAHSGSAARMAAGSVTTLAFHVASGQLKNGFAIVRPPGHHAEESAVMGFCVFNSVAIAAKLLLQELH--VRRILIVDLDVHHGNGTQQAFYNDPRVLYLSLHRYDNGNFFPGS--GASSEVGVGPGEGFTVNVSWTGGLDPPMGDADYLAAFRTVVMPIAMEFEPDVVLVSAGFDALDGHPPQLGGYKLTASC 905 HSP 2 Score: 187.193 bits (474), Expect = 8.763e-49 Identity = 108/296 (36.49%), Postives = 161/296 (54.39%), Query Frame = 2
Query: 254 PNKTAF----VYDEQMLLH--SNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHV---------QLIEDTQTMTAIQLKEL--------SSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLN---KTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCP 1063
PN+ +F VYD M+ H S D+ + E R+ + + +T LL C I ++ + I HS+ HV + DTQ + Q +L D + D ++ A+ ++AGS + V + KNGF ++RPPGHHA ES GFC+FN+V IAAK ++ILIVD DVHHGN TQ FYN +VLY+S+HRY++GNF+P S+ +G G G+ +N+ M ++DYL+ F ++++PIA E+ P++VL+SAGFD+ G P
Sbjct: 600 PNRPSFSTGVVYDTLMVRHQCSCGDDSNHPEHAGRIMAIWARLQQTGLLSKCEVIAGRKASLKDIQTVHSELHVLRYGTNPLNRQKLDTQGLLDAQPTQLMLLRCGGVGVDSDTYWSDAHSGSAARMAAGSVTTLAFHVASGQLKNGFAIVRPPGHHAEESAVMGFCVFNSVAIAAKLLLQELHVRRILIVDLDVHHGNGTQQAFYNDPRVLYLSLHRYDNGNFFPGSGASS--EVGVGPGEGFTVNVSWTGGLDPPMGDADYLAAFRTVVMPIAMEFEPDVVLVSAGFDALDGHP 893
BLAST of Histone deacetylase,putative vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001508.1 (pep scaffold:Pmarinus_7.0:GL487756:6232:7801:1 gene:ENSPMAG00000001367.1 transcript:ENSPMAT00000001508.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 119.013 bits (297), Expect = 1.312e-31 Identity = 52/120 (43.33%), Postives = 83/120 (69.17%), Query Frame = 2
Query: 440 HSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQF 799
+S ++ L+E T++M+ +LK LS + FF +T + ++ G+T++++ AV+ +NG L+RPPGHH+ +EA+GFCIFNNV IAA+ A+ + ++ILIVDWD+HHG TQ+ F
Sbjct: 1 YSAEYLALVESTESMSLEELKALSDKTMDAFFHPDTYACARLALGATLQLVDAVVTGAVRNGVALVRPPGHHSQRNEANGFCIFNNVAIAAERAKRTHGLRRILIVDWDIHHGQGTQFIF 120 HSP 2 Score: 97.0561 bits (240), Expect = 5.652e-24 Identity = 44/87 (50.57%), Postives = 58/87 (66.67%), Query Frame = 2
Query: 1796 SYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQF 2056
+Y A L+ G L ++D V + NG A++RPPGHH++ N GFC FNNVAIAA A K + +++ILIVDWD+HHG GTQ F
Sbjct: 36 TYACARLALGATLQLVDAVVTGAVRNGVALVRPPGHHSQRNEANGFCIFNNVAIAAERA--KRTHGLRRILIVDWDIHHGQGTQFIF 120
BLAST of Histone deacetylase,putative vs. Ensembl Sea Lamprey
Match: hdac3 (histone deacetylase 3 [Source:NCBI gene;Acc:393965]) HSP 1 Score: 92.8189 bits (229), Expect = 4.724e-20 Identity = 102/431 (23.67%), Postives = 179/431 (41.53%), Query Frame = 2
Query: 1571 HPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQH------------SYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPG-HHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINFPINKSGIEAIRKTLEYQKPYWKCLKFYEPLVVTYTEISP---NQTNPAALDNIVQIDTNTL-----AESVRQLGIVEVTFQTEQSIEETL-SQPRNDTFITEPNSSN 2797
HP P R + + L + + AS+ ++ HS Y++ L + +P F + N+ + Y A L LN +++C AI G HHA+ GFC+ N++ IA L KY ++L +D D+HHG+G Q F+ V+ +S H+Y N FFPG+ G VG + ++VN+ + + D Y F I+ + + P +++ G D+ D LG ++ + G + S N +++ GGY + ++ C + Y T+ ++N PI+ + PY + L+++ P + +IS NQ + L+ I Q L A SV+ + E+ E ++P D I +P+++N
Sbjct: 4 HPMKPHRLALTHSLVLHYGLHKKMMVYKPYRASQHDMCRFHSEEYIDFLQRV---TPHNIQGFTKSLNTFNVGDDCPVFPGLFEFCARYTGASLQGATQLN--NKMCD------IAINWSGGLHHAKKFEASGFCYVNDIVIAI-LELLKYH---PRVLYIDIDIHHGDGVQEAFYLTDRVMTVSFHKYGN-YFFPGT--GDMYEVGAESGRYYSVNVPL-RDGIDDQCYRLLFQPIIKQVMDFYQPTCIVLQCGADSLGCDRLGCFNLSIKGHGECVDFVKSF-NIPLLVLGGGGYTVRNVARCWT--------YETSLLMNDPISD------------ELPYNEYLEYFSPDFSLHPDISTRIENQNSKQYLEQIRQSIFENLKMLNHAPSVQIHEVPSDLLSYERKDEPNPDARPGTDDAIVKPDAAN 394 HSP 2 Score: 86.6557 bits (213), Expect = 5.793e-18 Identity = 58/181 (32.04%), Postives = 94/181 (51.93%), Query Frame = 2
Query: 650 HHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDS----AIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESL 1180
HHA + EASGFC N++ IA +L ++L +D D+HHG+ Q FY T +V+ +S H+Y GN++ Y+ +GA GR Y++N+PL + + + Y +F II + Y P +++ G DS +GC S+ H C + + L +VL GGY + ++
Sbjct: 116 HHAKKFEASGFCYVNDIVIAI--LELLKYHPRVLYIDIDIHHGDGVQEAFYLTDRVMTVSFHKY--GNYFFPGTGDMYE-VGAESGRYYSVNVPL-RDGIDDQCYRLLFQPIIKQVMDFYQPTCIVLQCGADSLGCDRLGCFNLSIKGHGECVDFVKSFNIPL-----LVLGGGGYTVRNV 285
BLAST of Histone deacetylase,putative vs. Ensembl Yeast
Match: HDA1 (Putative catalytic subunit of a class II histone deacetylase complex; role in azole resistance via Hsp90p, and in the heat shock response; Hda1p interacts with the Hda2p-Hda3p subcomplex to form an active tetramer; deletion increases histone H2B, H3 and H4 acetylation; other members of the HDA1 histone deacetylase complex are Hda2p and Hda3p [Source:SGD;Acc:S000004966]) HSP 1 Score: 290.426 bits (742), Expect = 4.821e-85 Identity = 151/379 (39.84%), Postives = 213/379 (56.20%), Query Frame = 2
Query: 1508 PNKTCFVYDCRMENHMNERSI-------HPESPRRTQMIFEFLRDNSLLSR------------CKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINFPINKSG---IEAIRKTLEYQKPYWKCLK 2578
P KT YD RM H + HPE PRR I++ L +N L++ ++ R A+ +EI +H+ ++E + + + S E+ +S+Y N SY SA L CG + V R +N A++RPPGHHAE GFC F+NVA+AA L Y ES+++I+I+DWD+HHGNGTQ F+ + VLY+SLHR++ G ++PG+ G G EGFN NI W V D+EY+ AF +VMP+ EF PDLVI+S+GFDAA GD +G VTP C+G+MT ML SLA G + + LEGGYNL+ I+ L+G P +++ + P++ IE I K + Q YW C +
Sbjct: 55 PLKTGLCYDVRMRYHAKIFTSYFEYIDPHPEDPRRIYRIYKILAENGLINDPTLSGVDDLGDLMLKIPVRAATSEEILEVHTKEHLEFIESTEKMSREELLKETEKGDSVYFNNDSYASARLPCGGAIEACKAVVEGRVKNSLAVVRPPGHHAEPQAAGGFCLFSNVAVAAKNILKNYPESVRRIMILDWDIHHGNGTQKSFYQDDQVLYVSLHRFEMGKYYPGTIQGQYDQTGEGKGEGFNCNITWPVGGVGDAEYMWAFEQVVMPMGREFKPDLVIISSGFDAADGDTIGQCHVTPSCYGHMTHMLKSLARGNLCVVLEGGYNLDAIARSALSVAKVLIGEPPDELPD-PLSDPKPEVIEMIDKVIRLQSKYWNCFR 432 HSP 2 Score: 263.462 bits (672), Expect = 1.336e-75 Identity = 132/375 (35.20%), Postives = 213/375 (56.80%), Query Frame = 2
Query: 254 PNKTAFVYDEQMLLHSNMWDNLYFE-------RPDRLRVCYEGICETNLLED------------CIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNY--STQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKL-EKFDEPCDSVKETIQNCLKFLHFFW 1312
P KT YD +M H+ ++ + YFE P R+ Y+ + E L+ D ++I + +E I H++ H++ IE T+ M+ +L + + + D V+F+N++ ++ + G IE KAV++ R KN ++RPPGHHA A GFC+F+NV +AAK NY S ++I+I+DWD+HHGN TQ FY +VLY+S+HR+E G ++P + YD G +G G+N NI + +++Y+ F +++P+ E+ P+LV+IS+GFD+A G G V P+C+ HMTH L LARG + V+LEGGY ++++ S + L G+ P +L + +P V E I ++ +W
Sbjct: 55 PLKTGLCYDVRMRYHAKIFTS-YFEYIDPHPEDPRRIYRIYKILAENGLINDPTLSGVDDLGDLMLKIPVRAATSEEILEVHTKEHLEFIESTEKMSREELLKETEKGDSVYFNNDSYASARLPCGGAIEACKAVVEGRVKNSLAVVRPPGHHAEPQAAGGFCLFSNVAVAAKNILKNYPESVRRIMILDWDIHHGNGTQKSFYQDDQVLYVSLHRFEMGKYYPGTIQGQYDQTGEGKGEGFNCNITWPVGGVGDAEYMWAFEQVVMPMGREFKPDLVIISSGFDAADGDTIGQCHVTPSCYGHMTHMLKSLARGNLCVVLEGGYNLDAIARSALSVAKVLIGEPPDELPDPLSDPKPEVIEMIDKVIRLQSKYW 428
BLAST of Histone deacetylase,putative vs. Ensembl Yeast
Match: HOS2 (Histone deacetylase and subunit of Set3 and Rpd3L complexes; required for gene activation via specific deacetylation of lysines in H3 and H4 histone tails; subunit of the Set3 complex, a meiotic-specific repressor of sporulation specific genes that contains deacetylase activity; co-localizes with Cmr1p in nuclear foci in response to DNA damage by MMS [Source:SGD;Acc:S000003162]) HSP 1 Score: 114.005 bits (284), Expect = 5.846e-27 Identity = 94/329 (28.57%), Postives = 160/329 (48.63%), Query Frame = 2
Query: 1472 YELRTKN-----AFNN-YPNKTCFVYDCRMENHMNERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESP-TIYHLFEEEFN-----SIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPG-HHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGG 2419
Y+++TK FN+ Y + + ++ ++ +H + HP P R + + L E+R A++DE+ HS +YV L + E+ + E FN I+ N + Y + L G L+ ++ +++S+ AI G HHA+ N P GFC+ N++ ++ L +Y +IL +D D+HHG+G Q F+T V +S H+Y NG FFPG+ G + +G D + F +N+ + + D YI+ F +IV P+ F P L++ G D+ D LG + + G + + S G +L + GG
Sbjct: 7 YDVKTKENEPLFEFNSAYSPRVSYHFNSKV-SHYHYGVKHPMKPFRLMLTDHLVSSYGLHKIMDLYETRSATRDELLQFHSEDYVNFLSKVSPENANKLPRGTLENFNIGDDCPIFQNLYDYTT--LYTGASLDATRKLINNQSD--IAINWSGGLHHAKKNSPSGFCYVNDIVLSI-LNLLRYH---PRILYIDIDLHHGDGVQEAFYTTDRVFTLSFHKY-NGEFFPGT--GDLTEIGCDKGKHFALNVPL-EDGIDDDSYINLFKSIVDPLIMTFKPTLIVQQCGADSLGHDRLGCFNLNIKAHGECVKFVKSF--GLPMLVVGGG 320 HSP 2 Score: 88.9669 bits (219), Expect = 8.810e-19 Identity = 62/236 (26.27%), Postives = 121/236 (51.27%), Query Frame = 2
Query: 419 NELIYYSHSQSHVQLI-----EDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPG--HHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDS----AIGCPEGSMDVHPAC 1093
+EL+ + HS+ +V + E+ + L+ + DC F N + + G++++ + ++++++ I G HHA ++ SGFC N++ + + L Y +IL +D D+HHG+ Q FY T +V +S H+Y +G F+P + IG ++G+ + +N+PL + + + Y+++F SI+ P+ + P L++ G DS +GC ++ H C
Sbjct: 79 DELLQF-HSEDYVNFLSKVSPENANKLPRGTLENFNIGDDCPIFQNLYDYTTLYT-GASLDATRKLINNQSD---IAINWSGGLHHAKKNSPSGFCYVNDI-VLSILNLLRYHP-RILYIDIDLHHGDGVQEAFYTTDRVFTLSFHKY-NGEFFPG--TGDLTEIGCDKGKHFALNVPL-EDGIDDDSYINLFKSIVDPLIMTFKPTLIVQQCGADSLGHDRLGCFNLNIKAHGEC 303
BLAST of Histone deacetylase,putative vs. Ensembl Yeast
Match: RPD3 (Histone deacetylase, component of both the Rpd3S and Rpd3L complexes; regulates transcription, silencing, autophagy and other processes by influencing chromatin remodeling; forms at least two different complexes which have distinct functions and members; Rpd3(L) recruitment to the subtelomeric region is regulated by interaction with the arginine methyltransferase, Hmt1p [Source:SGD;Acc:S000005274]) HSP 1 Score: 106.301 bits (264), Expect = 1.721e-24 Identity = 88/331 (26.59%), Postives = 156/331 (47.13%), Query Frame = 2
Query: 224 YDNIELRINFPNKTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIE----DTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPG-HHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWP---KLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDS----AIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESL 1180
+D I ++ + + A+ YD + ++ + + +P R+R+ + I L + +AK + + H+ ++ + D M + + + DC FD + S IS G ++E A +R K + G HHA +SEASGFC N++ + +L ++L +D DVHHG+ + FY T +V+ S H+Y G F+P +LR+ IG G+ Y +N+PL + + ++ Y S+F +I I Y P V++ G DS +GC SM+ H C ++ + + +V+ GGY M ++
Sbjct: 8 FDPITVKPSDKRRVAYFYDADVGNYA--YGAGHPMKPHRIRMAHSLIMNYGLYKKMEIYRAKPATKQEMCQFHTDEYIDFLSRVTPDNLEMFKRESVKFNVGDDCPVFDGLYEYCS-ISGGGSME--GAARLNRGKCDVAVNYAGGLHHAKKSEASGFCYLNDIVLGI--IELLRYHPRVLYIDIDVHHGDGVEEAFYTTDRVMTCSFHKY--GEFFPGTGELRD-----IGVGAGKNYAVNVPL-RDGIDDATYRSVFEPVIKKIMEWYQPSAVVLQCGGDSLSGDRLGCFNLSMEGHANCVNYVKSFGIPM-----MVVGGGGYTMRNV 318 HSP 2 Score: 99.7525 bits (247), Expect = 2.243e-22 Identity = 75/315 (23.81%), Postives = 142/315 (45.08%), Query Frame = 2
Query: 1514 KTCFVYDCRMENHMNERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFN-----SIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPG-HHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVIS 2440
+ + YD + N+ HP P R +M + + L + + ++ A+K E+ H+ Y++ L + ++ ++ +FN ++ + Y S +S G + + +R + A+ G HHA+ + GFC+ N++ + L +Y ++L +D DVHHG+G + F+T V+ S H+Y G FFPG+ + VG NV + + + D+ Y S F ++ I + P V++ G D+ GD LG ++ E N + S +++ GGY + ++
Sbjct: 20 RVAYFYDADVGNYAYGAG-HPMKPHRIRMAHSLIMNYGLYKKMEIYRAKPATKQEMCQFHTDEYIDFLSRVTPDNLEMFKRESVKFNVGDDCPVFDGLYEYCS--ISGGGSMEGAARL--NRGKCDVAVNYAGGLHHAKKSEASGFCYLNDIVLGI-IELLRYH---PRVLYIDIDVHHGDGVEEAFYTTDRVMTCSFHKY--GEFFPGTGELRDIGVGAGKNYAVNVPL---RDGIDDATYRSVFEPVIKKIMEWYQPSAVVLQCGGDSLSGDRLGCFNLSMEGHANCVNYVKSFGIPMMVVG-GGGYTMRNVA 319
BLAST of Histone deacetylase,putative vs. Ensembl Yeast
Match: HOS3 (Trichostatin A-insensitive homodimeric histone deacetylase (HDAC); specificity in vitro for histones H3, H4, H2A, and H2B; similar to Hda1p, Rpd3p, Hos1p, and Hos2p; deletion results in increased histone acetylation at rDNA repeats [Source:SGD;Acc:S000006037]) HSP 1 Score: 73.1738 bits (178), Expect = 1.574e-13 Identity = 70/277 (25.27%), Postives = 121/277 (43.68%), Query Frame = 2
Query: 623 GFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQ------------------------YQFYNTSKVLYISIHRYEDGNFWPK---------LRESNYDYIGANEGRGYNINIPLNKTN-----MTNSDYLSI-------FHSIILPIAYEYNP--ELVLISAGFDSA----IGCPEGSMDVHPACFAHMTHKLMDLAR----GRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNC 1288
F IRPPGHH SGFC+ NN +A +YA Y+ ++++D+D+HHG+ TQ +F KV Y S+H D N +P ++ ++ + +++ +NI++ T + + Y ++ F S L + + P LV+ISAGFD++ S++V + + T + LA+ G+V+ L+EGGY +++ V L L + K ++ VKE ++ C
Sbjct: 186 AFVAIRPPGHHCHYGTPSGFCLLNNAHVAIEYAYDTYNVTHVVVLDFDLHHGDGTQDICWKRAGFKPEEEPEDSSYDDFGKKFAEFPKVGYFSMH---DINSFPTESGFATKENIKNASTCIMNSHDLNIWNIHLSKWTTEEEFNVLYRTKYRTLFAKADEFFRSAKLEMNQQGRPFKGLVVISAGFDASEFEQTSMQRHSVNVPTSFYTTFTKDALKLAQMHCHGKVLSLMEGGYSDKAICSGVFAHLIGLQNQDWVKEWGSEQ---VVKEIVRGC 456 HSP 2 Score: 70.4774 bits (171), Expect = 9.987e-13 Identity = 70/293 (23.89%), Postives = 117/293 (39.93%), Query Frame = 2
Query: 1865 SENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNK------------------------NVLYISLHRYDNGLFFPGST---------DGSPSAVGGDDAEGFNVNIA-WNKRPVRDSEYISA-----------FINIVMPISHEFNP--DLVIVSAGFDAARGDPLG----GLTVTPECFGNMTQMLTSLA----NGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINFPINKSGIEAIRKTLEYQKPYWKCLK 2578
S F IRPPGHH P GFC NN +A YA Y ++ ++++D+D+HHG+GTQ W V Y S+H ++ FP + + S + D +N++++ W + Y + F + + ++ + P LV++SAGFDA+ + + V + T+ LA +GKV+ +EGGY+ I C S + L+G + + +++ + KP WK K
Sbjct: 183 SNRAFVAIRPPGHHCHYGTPSGFCLLNNAHVAIEYAYDTY--NVTHVVVLDFDLHHGDGTQDICWKRAGFKPEEEPEDSSYDDFGKKFAEFPKVGYFSMHDINS---FPTESGFATKENIKNASTCIMNSHDLNIWNIHLSKWTTEEEFNVLYRTKYRTLFAKADEFFRSAKLEMNQQGRPFKGLVVISAGFDASEFEQTSMQRHSVNVPTSFYTTFTKDALKLAQMHCHGKVLSLMEGGYSDKAI--C-SGVFAHLIGLQNQDWVK---EWGSEQVVKEIVRGCKPAWKPYK 464
BLAST of Histone deacetylase,putative vs. Ensembl Yeast
Match: HOS1 (Class I histone deacetylase (HDAC) family member; deacetylates Smc3p on lysine residues at anaphase onset; has sequence similarity to Hda1p, Rpd3p, Hos2p, and Hos3p; interacts with the Tup1p-Ssn6p corepressor complex [Source:SGD;Acc:S000006272]) HSP 1 Score: 68.1662 bits (165), Expect = 4.005e-12 Identity = 63/207 (30.43%), Postives = 93/207 (44.93%), Query Frame = 2
Query: 1823 GLLLNVIDEVCSDRSENGFAIIRPPG-HHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVR---DSEYISAFIN-IVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGN-MTQMLTSLANGKVILALEGGYN 2425
G LN++D + +E I G HHA GFC+ N+V + L K + KI VD+D+HHG+G + F +K + IS+H Y+ G FFPG+ GS S D VNI P++ D Y+ + IV P+ P+ +I+ G D GD +T + ++ S + L GGYN
Sbjct: 185 GATLNLLDHLSP--TERLIGINWDGGRHHAFKQRASGFCYINDVVLLIQ-RLRK--AKLNKITYVDFDLHHGDGVEKAFQYSKQIQTISVHLYEPG-FFPGT--GSLSDSRKDKNV---VNI-----PLKHGCDDNYLELIASKIVNPLIERHEPEALIIECGGDGLLGDRFNEWQLTIRGLSRIIINIMKSYPRAHIFLLGGGGYN 375 HSP 2 Score: 65.855 bits (159), Expect = 1.951e-11 Identity = 54/180 (30.00%), Postives = 85/180 (47.22%), Query Frame = 2
Query: 650 HHAMESEASGFCIFNNVGI---AAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWP---KLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHS-IILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMD-LARGRVVVLLEGGY 1165
HHA + ASGFC N+V + + A+LN KI VD+D+HHG+ + F + ++ IS+H YE G F+P L +S D +NIPL + +YL + S I+ P+ + PE ++I G D +G + + + +M R + +L GGY
Sbjct: 210 HHAFKQRASGFCYINDVVLLIQRLRKAKLN----KITYVDFDLHHGDGVEKAFQYSKQIQTISVHLYEPG-FFPGTGSLSDSRKD--------KNVVNIPLKHG--CDDNYLELIASKIVNPLIERHEPEALIIECGGDGLLGDRFNEWQLTIRGLSRIIINIMKSYPRAHIFLLGGGGY 374
BLAST of Histone deacetylase,putative vs. Ensembl Nematostella
Match: EDO33321 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SSG8]) HSP 1 Score: 301.212 bits (770), Expect = 1.689e-92 Identity = 148/369 (40.11%), Postives = 224/369 (60.70%), Query Frame = 2
Query: 263 TAFVYDEQMLLHSNMWDNL---------YFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAK------NGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLS 1324
T VYD++M H N+WD +E PDR+ YE E LL+ C +I ++ E + HS+ H+ ++ TQ M L L ++D ++ + + +S G T+ ++ V +++ N +RPPGHHA A G+C FNNV IAAK AQ + Q+ILIVDWD+HHGN TQ F + VLY S+HRY+ NF+P ++NYD +G +G+G+N+N+P NK+++ ++DY++ F I+LPIAYE++P++VL+SAGFDSA G P+G D+ P + H+T+ LM LA G+VVV+LEGGY + S+ +S+ +TL G P+L+ PC SV ++I N + FWK+L+
Sbjct: 1 TGLVYDDRMKRHVNIWDKYVYINTLICSLYEVPDRIGRPYEKHKEYGLLDRCYKIPSRHATEEDLLCLHSKEHIDKMKSTQDMKPRDLFNLGEEYDSIYMSKDVYDCALLSCGCTLAAVEHVATNKSSKHSIHINQLFFLRPPGHHADADSAMGYCFFNNVAIAAKLAQQRWGMQRILIVDWDIHHGNGTQNLFESDPSVLYFSLHRYDHANFYPFSAQANYDIVGKGQGKGFNVNVPWNKSHIGDADYIAAFQQILLPIAYEFDPDIVLVSAGFDSARGDPKGYCDITPEGYCHLTNMLMSLAGGKVVVILEGGYNITSVAESMCSCTSTLLGDPCPRLDGPMVPCQSVLKSISNVVNVHKQFWKNLT 369 HSP 2 Score: 293.893 bits (751), Expect = 9.491e-90 Identity = 151/371 (40.70%), Postives = 236/371 (63.61%), Query Frame = 2
Query: 1517 TCFVYDCRMENHMN--ERSIHP--------ESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSE------NGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINFPI--NKSGIEAIRKTLEYQKPYWKCL 2575
T VYD RM+ H+N ++ ++ E P R +E ++ LL RC ++ SR A+++++ +HS +++ + + P EE++SIY+++ Y ALLSCG L ++ V +++S N +RPPGHHA+ + +G+CFFNNVAIAA A ++ +++ILIVDWD+HHGNGTQ+ F ++ +VLY SLHRYD+ F+P S + VG +GFNVN+ WNK + D++YI+AF I++PI++EF+PD+V+VSAGFD+ARGDP G +TPE + ++T ML SLA GKV++ LEGGYN+ +++ M C S+LLG P + ++ P+ +S +++I + K +WK L
Sbjct: 1 TGLVYDDRMKRHVNIWDKYVYINTLICSLYEVPDRIGRPYEKHKEYGLLDRCYKIPSRHATEEDLLCLHSKEHIDKMKSTQDMKPRDLFNLGEEYDSIYMSKDVYDCALLSCGCTLAAVEHVATNKSSKHSIHINQLFFLRPPGHHADADSAMGYCFFNNVAIAAKLAQQRWG--MQRILIVDWDIHHGNGTQNLFESDPSVLYFSLHRYDHANFYPFSAQANYDIVGKGQGKGFNVNVPWNKSHIGDADYIAAFQQILLPIAYEFDPDIVLVSAGFDSARGDPKGYCDITPEGYCHLTNMLMSLAGGKVVVILEGGYNITSVAESMCSCTSTLLGDPCPR-LDGPMVPCQSVLKSISNVVNVHKQFWKNL 368
BLAST of Histone deacetylase,putative vs. Ensembl Nematostella
Match: EDO35756 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SKN6]) HSP 1 Score: 269.24 bits (687), Expect = 3.358e-80 Identity = 145/361 (40.17%), Postives = 210/361 (58.17%), Query Frame = 2
Query: 1571 HPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQ-----ESPTIYHL----------FEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKR---PVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDP--LGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLG-----YPTNQIINFPINKSGIEAIRKTLEYQKPYWKCLK 2578
HPE P R Q I+ L++ +++ C ++ R A+ EI +HS + G Q E TI L + ++I+ HS +A ++ G ++ + +V + +NG AI+RPPGHHAE + +GFC+FNNVAIAA L + SI ++LIVDWD+HHGNGTQ F+ + +VLYISLHR+D+G FFPG+ G G G+NVNIAW+ P D+EY++AF ++V+PI+ EF PD+++VS GFDAA G LGG V+ CF ++T L LA+G+V+LALEGGY+L + D C+ +LL P + P N + I + KT+ Q YW +K
Sbjct: 14 HPEHPGRLQSIWARLQETGVVNMCDRVRPRKATLAEILSVHSEQHTMLFGGSTQCRTKAEDGTITTLKCFSSLPCGGMGVDGDTIWNEVHSANAARMAVGCVVELTQKVAAQEIKNGMAIVRPPGHHAEAHQAMGFCYFNNVAIAAR--LLRLKMSIDRVLIVDWDIHHGNGTQQMFYDDPHVLYISLHRHDDGTFFPGT--GKAEECGAGIGVGYNVNIAWSGGLDPPYGDAEYLAAFRSVVIPIAKEFQPDIILVSCGFDAAAGHSPQLGGYKVSAPCFAHLTNQLMDLADGRVVLALEGGYSLPSLCDAAEACLRALLSDTLPEIPKESLKRAP-NPNAIAVLEKTIAIQSRYWSSVK 369 HSP 2 Score: 228.794 bits (582), Expect = 7.550e-66 Identity = 126/326 (38.65%), Postives = 188/326 (57.67%), Query Frame = 2
Query: 326 ERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIE-DTQTMTAIQ------LKELSS--------QHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKT---NMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIG-CPE-GSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEK 1243
E P RL+ + + ET ++ C R++ ++ I HS+ H L TQ T + LK SS D ++ + ++ A+ ++ G +E+ + V KNG ++RPPGHHA +A GFC FNNV IAA+ +L S ++LIVDWD+HHGN TQ FY+ VLYIS+HR++DG F+P ++ + GA G GYN+NI + +++YL+ F S+++PIA E+ P+++L+S GFD+A G P+ G V CFAH+T++LMDLA GRVV+ LEGGY + SL D+ L L P++ K
Sbjct: 16 EHPGRLQSIWARLQETGVVNMCDRVRPRKATLAEILSVHSEQHTMLFGGSTQCRTKAEDGTITTLKCFSSLPCGGMGVDGDTIWNEVHSANAARMAVGCVVELTQKVAAQEIKNGMAIVRPPGHHAEAHQAMGFCYFNNVAIAARLLRLKMSIDRVLIVDWDIHHGNGTQQMFYDDPHVLYISLHRHDDGTFFPGTGKA--EECGAGIGVGYNVNIAWSGGLDPPYGDAEYLAAFRSVVIPIAKEFQPDIILVSCGFDAAAGHSPQLGGYKVSAPCFAHLTNQLMDLADGRVVLALEGGYSLPSLCDAAEACLRALLSDTLPEIPK 339
BLAST of Histone deacetylase,putative vs. Ensembl Nematostella
Match: EDO32559 (Histone deacetylase [Source:UniProtKB/TrEMBL;Acc:A7SUP8]) HSP 1 Score: 102.449 bits (254), Expect = 4.558e-23 Identity = 56/194 (28.87%), Postives = 95/194 (48.97%), Query Frame = 2
Query: 1901 HHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYP 2482
HHA+ + GFC+ N++ + + K E ++L VD DVHHG+G + F V+ +S H+Y +G FFPG+ GS VG + +N+ K + D ++ F ++ + +F PD ++ G D+ GDP+ +T G + L N +++ GGYN+ S C ++ +L P
Sbjct: 149 HHAQRDEAAGFCYINDIVLG----ILKLREKYDRVLYVDLDVHHGDGVEDAFSFTPKVMTVSFHKYSSG-FFPGT--GSCCQVGHGKGRYYTLNVPL-KDGITDRPFVEVFTRVMSRVKAKFKPDAIVCQCGVDSLAGDPMKAFNLTQFAVGRCVKYLQGW-NLPMLVLGGGGYNMVNTSRCWTYVTGVILDRP 333 HSP 2 Score: 90.5077 bits (223), Expect = 3.762e-19 Identity = 64/221 (28.96%), Postives = 104/221 (47.06%), Query Frame = 2
Query: 497 LKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEG 1159
L E +DC F++ S I AG+T+ + +AK + HHA EA+GFC N+ I +L ++L VD DVHHG+ + F T KV+ +S H+Y G F+P + +G +GR Y +N+PL K +T+ ++ +F ++ + ++ P+ ++ G DS G P + + L A GR V L+G
Sbjct: 100 LVEFGLGYDCPPFEDMYDCVSMI-AGATLLAADMLKTGQAKVAVNW-QGGWHHAQRDEAAGFCYIND--IVLGILKLREKYDRVLYVDLDVHHGDGVEDAFSFTPKVMTVSFHKYSSG-FFPG--TGSCCQVGHGKGRYYTLNVPL-KDGITDRPFVEVFTRVMSRVKAKFKPDAIVCQCGVDSLAGDPMKAFN------------LTQFAVGRCVKYLQG 300
BLAST of Histone deacetylase,putative vs. Ensembl Nematostella
Match: EDO49920 (Histone deacetylase [Source:UniProtKB/TrEMBL;Acc:A7RFA3]) HSP 1 Score: 102.449 bits (254), Expect = 8.693e-23 Identity = 74/267 (27.72%), Postives = 124/267 (46.44%), Query Frame = 2
Query: 329 RPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIE----DTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPG-HHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWP---KLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDS----AIGCPEGSMDVHPAC 1093
+P R+R+ + + L + + E I HS +++ ++ D + Q++ + DC FD + + GS + AV ++ + G HHA +SEASGFC N++ +A +L Q++L +D D+HHG+ + FY T +V+ +S H+Y G ++P LR+ IGA G+ Y +N PL + + + Y IF II + Y P V++ G DS +GC S+ H C
Sbjct: 32 KPHRIRMTHNLLLNYGLYRKMEIYRPHKAAMEEITRYHSDDYIKFLKSIRPDNMSDYTKQMQRFNVGEDCPVFDGLYEFCQLSTGGS---IAGAVKLNKQHTDIAINWSGGLHHAKKSEASGFCYVNDIVLAI--LELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKY--GEYFPGTGDLRD-----IGAGRGKYYAVNFPL-RDGIEDESYQQIFQPIITKVIEIYQPNAVVLQCGADSLAGDRLGCFNLSLKGHAKC 285 HSP 2 Score: 101.293 bits (251), Expect = 1.863e-22 Identity = 83/325 (25.54%), Postives = 150/325 (46.15%), Query Frame = 2
Query: 1511 NKTCFVYDCRMENHMNERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFN---SIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPG-HHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLL 2473
K C+ YD + N+ + HP P R +M L + L + + A+ +EI HS +Y++ L +I ++ + Y + FN + Y LS G ++ V ++ AI G HHA+ + GFC+ N++ +A L KY + ++L +D D+HHG+G + F+T V+ +S H+Y G +FPG+ G +G + + VN + + D Y F I+ + + P+ V++ G D+ GD LG ++ + + + S N +++ GGY + ++ C ++ S L
Sbjct: 10 KKVCYYYDGDIGNYYYGQG-HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKAAMEEITRYHSDDYIKFLKSIRPDNMSDYTKQMQRFNVGEDCPVFDGLYEFCQLSTGG--SIAGAVKLNKQHTDIAINWSGGLHHAKKSEASGFCYVNDIVLAI-LELLKYHQ---RVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKY--GEYFPGT--GDLRDIGAGRGKYYAVNFPL-RDGIEDESYQQIFQPIITKVIEIYQPNAVVLQCGADSLAGDRLGCFNLSLKGHAKCVEFVKSF-NLPLLILGGGGYTIRNVARCWTYETSVAL 321
BLAST of Histone deacetylase,putative vs. Ensembl Nematostella
Match: EDO39062 (Histone deacetylase [Source:UniProtKB/TrEMBL;Acc:A7SB64]) HSP 1 Score: 97.8265 bits (242), Expect = 2.460e-21 Identity = 94/397 (23.68%), Postives = 168/397 (42.32%), Query Frame = 2
Query: 1571 HPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLG-----------------NICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPG-HHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINFPINKSGIEAIRKTLEYQKPYWKCLKFYEPLVVTYTEISP---NQTNPAALDNIVQIDTNTLAESVRQL 2698
HP P R + + + L + + + A+ ++ HS +Y++ L N+ ++ P LF+ F SIY A L + LN +C AI G HHA+ GFC+ N++ +A L KY ++L VD D+HHG+G Q F+ V+ +S H+Y N FFPG+ G VG D+ ++VN+ + + D Y S F ++ + + P +++ G D+ D LG ++ + G + + + ++L GGY + ++ C ++ S L + + + + PY L+++ P + +I+ NQ LD I Q T++E+++ L
Sbjct: 23 HPMKPHRLTLTHNLVFNYGLHKKMEVYKPYRATNHDMSRFHSSDYIDFLSRVTIQNNPNLSKSMSDFNVGEDCPVFPGLFD--FCSIYT------GASLEGAVRLN--QGICD------IAINWAGGLHHAKKCEASGFCYVNDIVVAI-LELLKYH---NRVLYVDIDIHHGDGVQEAFYLTDRVMTVSFHKYGNH-FFPGT--GDMYEVGVDNGRLYSVNVPL-RDGIDDQNYASLFKPVINMVIDHYQPTCIVLQCGADSLGCDRLGCFNLSTKGHGECVRFMKTFNLPMLVLG-GGGYTIRNVARCWAYETSLL--------------------VDQQVSTEIPYNDYLEYFGPDFSLHPDIASRIENQNTKQYLDQIRQ----TVSENLKNL 370 HSP 2 Score: 90.8929 bits (224), Expect = 4.470e-19 Identity = 74/236 (31.36%), Postives = 119/236 (50.42%), Query Frame = 2
Query: 497 LKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFC--LIRPPG--HHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDS----AIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESL 1180
+ + + DC F S I G+++E AV R G C I G HHA + EASGFC N++ + A L Y ++L VD D+HHG+ Q FY T +V+ +S H+Y + +F+P + Y+ +G + GR Y++N+PL + + + +Y S+F +I + Y P +++ G DS +GC S H C M K +L ++VL GGY + ++
Sbjct: 86 MSDFNVGEDCPVFPGLFDFCS-IYTGASLE--GAV---RLNQGICDIAINWAGGLHHAKKCEASGFCYVNDI-VVAILELLKYHN-RVLYVDIDIHHGDGVQEAFYLTDRVMTVSFHKYGN-HFFPGTGDM-YE-VGVDNGRLYSVNVPL-RDGIDDQNYASLFKPVINMVIDHYQPTCIVLQCGADSLGCDRLGCFNLSTKGHGECVRFM--KTFNLP---MLVLGGGGYTIRNV 304
BLAST of Histone deacetylase,putative vs. Ensembl Medaka
Match: hdac6 (histone deacetylase 6 [Source:NCBI gene;Acc:101163380]) HSP 1 Score: 739.954 bits (1909), Expect = 0.000e+0 Identity = 416/1087 (38.27%), Postives = 584/1087 (53.73%), Query Frame = 2
Query: 185 DEDLPAAQSNHGLYDNIELRINFPNKTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKENDQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMN--ERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIIN--FPINKSGIEAIRKTLEYQKPYWKCLKFYEPLVVTYTEISPNQTNPAALDNIV----QIDTNTLAESVRQLGIVEVTFQTEQSIEETLSQPRNDTFITEPNSSNPIIHLPPIVSSDNAVEVPATTSINSTTHATQNISANFLSVD-QSSGATPVSANVSRVINEGNSVGLVLQDIMNLSGVSN-SDIHHFLGLTSNDPLPERVYAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQVFCGRFVQAHMMQHFQNTRHAIVLSFVDLSSWCYECDSYVHNECLNHAKREAHIAKFGVPQP 3415
DE+L + GL R T VY E H N+W+ + E PDR+R E + LL C+ +Q + E + H++ ++ L++ T+TMT +L+ L ++D V+ + I+AGS ++++ V+ +NGF +IRPPGHHA SE +GFC+FNNV IAA+YA ++ ++LIVDWDVHHG QY F +LY SIHRYE +FWP L ES+ ++G+ G NIN+P NK M+++DY+S F ++LP+AYE+ P+LVL+SAGFD+A G P+G M+V P CF +TH LM LA GR+V++LEGGY +++ + + L G+A P L P +S +I + L+ W L V + + + + T ++ P L T VYD RM H+N +R HPE P+R IF + L+ RC+ ++SRLA+++E+ + HS +++ + P H +EF SI+I+ S+ SA L+ G ++ + + + N AI+RPPGHHAE+++P GFC FN A+ A +A K S ++ ILI+DWDVHHGNGTQH F + +VLYISLHRYDNG FFP S DG+P VG G+NVN+AW+ + DS+Y++AF +VMPI+ EFNP LV+VSAGFDAA+GDPLGG VTPE + + T ML SLA G+V+ LEGGYNL ISD M+ C S LLG P + P + AI K +++ PYWK L+ P V SP V Q L S+ Q G+ E L Q I++ P S +AV + + S H+ L D QS A P + + E + +D L G + GL + +Y V PL WC HL V+ P + IDV+ C C S ENW+CLTCYQVFCGR+V HM+ H + H +VLSF DLS WCY C+SY+H++ L AK AH +KFG P
Sbjct: 55 DEELSSIMGALGLSGRSAAR-----GTGLVYSEIFTRHQNLWEPSHPESPDRVRSIMEELERQQLLPCCVSVQPRAATEEELLLVHTKDYIDLVKSTETMTQSELQTLCCKYDSVYLHPLSFKVCAIAAGSVLQLVDEVMAFNLRNGFAVIRPPGHHAQTSEPNGFCVFNNVAIAARYACSRHAVSRVLIVDWDVHHGQGLQYLFQEDPSILYFSIHRYEHASFWPHLPESDSSFVGSGHAIGRNINLPWNKIGMSDADYISAFQHVLLPVAYEFQPQLVLVSAGFDAAAGDPKGEMNVSPQCFHTLTHMLMSLAEGRLVLVLEGGYNLKATAEGAAACVRALLGRACPPLNPPTGPSESAMHSISQTISALYVHWAFLQV-LEGTSSAEADSTKTVSGHTSTTTVAPALAAA-----------------------------TITGLVYDERMMEHVNLWDRH-HPEQPQRIFKIFSRHQQLGLVDRCQLIQSRLATEEELAMCHSLQHIQQMSATATMKPRDLHRLGDEFVSIFISNQSFQSAQLAAGSCFAAVEHMLNGQVNNAVAIVRPPGHHAEMDFPCGFCLFNTTALTARHA-QKVSHDLQ-ILILDWDVHHGNGTQHIFEDDNSVLYISLHRYDNGAFFPSSKDGAPENVGVAKGAGYNVNLAWSGGRMGDSDYLAAFHQVVMPIATEFNPGLVLVSAGFDAAQGDPLGGYHVTPEGYAHFTHMLMSLAGGRVLFILEGGYNLKSISDSMAACTSVLLGDPPPSLATPLPPPHHCAAVAINKVIQHHAPYWKSLRVQIPESVRAFLPSPKHRGKHGPKGRVRKSEQNSMGRLESSIVQSGL------------EQLMQGLAGLDISQ----------SPANQSLSAVSLSVRS--ESDPHSDTVEEMRVLKGDSQSRIALP------QTVAEVTPEMAIPKDKPQLEGACGWAGCQKDTGLMCAE--ETSLYVVDPLPWCSHLGSVKPLPPSG-IDVSRPCQDCGSEAENWICLTCYQVFCGRYVNEHMVAHGKEVEHPMVLSFSDLSVWCYMCESYIHHQVLFQAKNAAHFSKFGEESP 1070
BLAST of Histone deacetylase,putative vs. Ensembl Medaka
Match: hdac10 (histone deacetylase 10 [Source:NCBI gene;Acc:101158373]) HSP 1 Score: 327.02 bits (837), Expect = 1.287e-97 Identity = 158/349 (45.27%), Postives = 222/349 (63.61%), Query Frame = 2
Query: 263 TAFVYDEQMLLHSNMWDN--LYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLH 1303
TA +YDE+M + +W + E P+RL V + + L + CI + +E + I HS+ +++ ++ T MT LKE + Q+ V+F N + ++ GS ++++ +VL + KNG L+RPPGHH+M S A+GFC+FNNV IAA+YA+ Y ++ILIVDWD+HHG QY F + VLY S HRYE FWP L++S+YD +G EG G+NIN+P NK M NSDYLS+F ++LPIAYE+ P+LVL+ AGFDSAIG EG M P FAH+T+ LM+LA G++ +LEGGY + SL SV T+ TL G P L PC S E++Q C++ H
Sbjct: 3 TALIYDEEMTKYKLLWVDPACKIEVPERLTVSHGALVRNGLTDRCICLPVREAVDAEILLVHSEEYLEAVKQTPHMTLEDLKEFTLQYGDVYFHPNIYHCAKLAVGSALQLVDSVLMGKVKNGMALVRPPGHHSMRSAANGFCVFNNVAIAAQYAKQKYGVKRILIVDWDIHHGQGVQYCFEDDPSVLYFSWHRYEHQKFWPNLKDSDYDIVGKGEGAGFNINVPWNKVGMENSDYLSVFCHVLLPIAYEFCPDLVLVCAGFDSAIGDLEGEMCATPDIFAHLTYLLMNLAEGKLCAVLEGGYNLTSLAQSVCQTVQTLLGDPLPPLTNLTGPCRSTLESLQ-CVRAAH 350 HSP 2 Score: 257.684 bits (657), Expect = 5.503e-73 Identity = 136/358 (37.99%), Postives = 204/358 (56.98%), Query Frame = 2
Query: 1517 TCFVYDCRMENH---MNERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINFP-INKSGIEAIRKTLEYQKPYWKCLK 2578
T +YD M + + + E P R + L N L RC L R A EI L+HS Y+E++ + F ++ +Y + + Y A L+ G L ++D V + +NG A++RPPGHH+ + GFC FNNVAIAA YA KY +K+ILIVDWD+HHG G Q+ F + +VLY S HRY++ F+P D VG + GFN+N+ WNK + +S+Y+S F ++++PI++EF PDLV+V AGFD+A GD G + TP+ F ++T +L +LA GK+ LEGGYNL ++ + V +LLG P + N +S +E+++ + +W CL+
Sbjct: 3 TALIYDEEMTKYKLLWVDPACKIEVPERLTVSHGALVRNGLTDRCICLPVREAVDAEILLVHSEEYLEAVKQTPHMTLEDLKEFTLQYGDVYFHPNIYHCAKLAVGSALQLVDSVLMGKVKNGMALVRPPGHHSMRSAANGFCVFNNVAIAAQYAKQKYG--VKRILIVDWDIHHGQGVQYCFEDDPSVLYFSWHRYEHQKFWPNLKDSDYDIVGKGEGAGFNINVPWNKVGMENSDYLSVFCHVLLPIAYEFCPDLVLVCAGFDSAIGDLEGEMCATPDIFAHLTYLLMNLAEGKLCAVLEGGYNLTSLAQSVCQTVQTLLGDPLPPLTNLTGPCRSTLESLQCVRAAHRQHWSCLR 358
BLAST of Histone deacetylase,putative vs. Ensembl Medaka
Match: hdac10 (histone deacetylase 10 [Source:NCBI gene;Acc:101158373]) HSP 1 Score: 326.635 bits (836), Expect = 1.431e-97 Identity = 158/349 (45.27%), Postives = 222/349 (63.61%), Query Frame = 2
Query: 263 TAFVYDEQMLLHSNMWDN--LYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLH 1303
TA +YDE+M + +W + E P+RL V + + L + CI + +E + I HS+ +++ ++ T MT LKE + Q+ V+F N + ++ GS ++++ +VL + KNG L+RPPGHH+M S A+GFC+FNNV IAA+YA+ Y ++ILIVDWD+HHG QY F + VLY S HRYE FWP L++S+YD +G EG G+NIN+P NK M NSDYLS+F ++LPIAYE+ P+LVL+ AGFDSAIG EG M P FAH+T+ LM+LA G++ +LEGGY + SL SV T+ TL G P L PC S E++Q C++ H
Sbjct: 3 TALIYDEEMTKYKLLWVDPACKIEVPERLTVSHGALVRNGLTDRCICLPVREAVDAEILLVHSEEYLEAVKQTPHMTLEDLKEFTLQYGDVYFHPNIYHCAKLAVGSALQLVDSVLMGKVKNGMALVRPPGHHSMRSAANGFCVFNNVAIAAQYAKQKYGVKRILIVDWDIHHGQGVQYCFEDDPSVLYFSWHRYEHQKFWPNLKDSDYDIVGKGEGAGFNINVPWNKVGMENSDYLSVFCHVLLPIAYEFCPDLVLVCAGFDSAIGDLEGEMCATPDIFAHLTYLLMNLAEGKLCAVLEGGYNLTSLAQSVCQTVQTLLGDPLPPLTNLTGPCRSTLESLQ-CVRAAH 350 HSP 2 Score: 258.07 bits (658), Expect = 4.826e-73 Identity = 136/358 (37.99%), Postives = 204/358 (56.98%), Query Frame = 2
Query: 1517 TCFVYDCRMENH---MNERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINFP-INKSGIEAIRKTLEYQKPYWKCLK 2578
T +YD M + + + E P R + L N L RC L R A EI L+HS Y+E++ + F ++ +Y + + Y A L+ G L ++D V + +NG A++RPPGHH+ + GFC FNNVAIAA YA KY +K+ILIVDWD+HHG G Q+ F + +VLY S HRY++ F+P D VG + GFN+N+ WNK + +S+Y+S F ++++PI++EF PDLV+V AGFD+A GD G + TP+ F ++T +L +LA GK+ LEGGYNL ++ + V +LLG P + N +S +E+++ + +W CL+
Sbjct: 3 TALIYDEEMTKYKLLWVDPACKIEVPERLTVSHGALVRNGLTDRCICLPVREAVDAEILLVHSEEYLEAVKQTPHMTLEDLKEFTLQYGDVYFHPNIYHCAKLAVGSALQLVDSVLMGKVKNGMALVRPPGHHSMRSAANGFCVFNNVAIAAQYAKQKYG--VKRILIVDWDIHHGQGVQYCFEDDPSVLYFSWHRYEHQKFWPNLKDSDYDIVGKGEGAGFNINVPWNKVGMENSDYLSVFCHVLLPIAYEFCPDLVLVCAGFDSAIGDLEGEMCATPDIFAHLTYLLMNLAEGKLCAVLEGGYNLTSLAQSVCQTVQTLLGDPLPPLTNLTGPCRSTLESLQCVRAAHRQHWSCLR 358
BLAST of Histone deacetylase,putative vs. Ensembl Medaka
Match: hdac10 (histone deacetylase 10 [Source:NCBI gene;Acc:101158373]) HSP 1 Score: 315.849 bits (808), Expect = 2.528e-93 Identity = 151/327 (46.18%), Postives = 210/327 (64.22%), Query Frame = 2
Query: 323 FERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLH 1303
E P+RL V + + L + CI + +E + I HS+ +++ ++ T MT LKE + Q+ V+F N + ++ GS ++++ +VL + KNG L+RPPGHH+M S A+GFC+FNNV IAA+YA+ Y ++ILIVDWD+HHG QY F + VLY S HRYE FWP L++S+YD +G EG G+NIN+P NK M NSDYLS+F ++LPIAYE+ P+LVL+ AGFDSAIG EG M P FAH+T+ LM+LA G++ +LEGGY + SL SV T+ TL G P L PC S E++Q C++ H
Sbjct: 56 IEVPERLTVSHGALVRNGLTDRCICLPVREAVDAEILLVHSEEYLEAVKQTPHMTLEDLKEFTLQYGDVYFHPNIYHCAKLAVGSALQLVDSVLMGKVKNGMALVRPPGHHSMRSAANGFCVFNNVAIAAQYAKQKYGVKRILIVDWDIHHGQGVQYCFEDDPSVLYFSWHRYEHQKFWPNLKDSDYDIVGKGEGAGFNINVPWNKVGMENSDYLSVFCHVLLPIAYEFCPDLVLVCAGFDSAIGDLEGEMCATPDIFAHLTYLLMNLAEGKLCAVLEGGYNLTSLAQSVCQTVQTLLGDPLPPLTNLTGPCRSTLESLQ-CVRAAH 381 HSP 2 Score: 256.914 bits (655), Expect = 2.113e-72 Identity = 133/336 (39.58%), Postives = 197/336 (58.63%), Query Frame = 2
Query: 1577 ESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINF--PINKSGIEAIRKTLEYQKPYWKCLK 2578
E P R + L N L RC L R A EI L+HS Y+E++ + F ++ +Y + + Y A L+ G L ++D V + +NG A++RPPGHH+ + GFC FNNVAIAA YA KY +K+ILIVDWD+HHG G Q+ F + +VLY S HRY++ F+P D VG + GFN+N+ WNK + +S+Y+S F ++++PI++EF PDLV+V AGFD+A GD G + TP+ F ++T +L +LA GK+ LEGGYNL ++ + V +LLG P + N P +S +E+++ + +W CL+
Sbjct: 57 EVPERLTVSHGALVRNGLTDRCICLPVREAVDAEILLVHSEEYLEAVKQTPHMTLEDLKEFTLQYGDVYFHPNIYHCAKLAVGSALQLVDSVLMGKVKNGMALVRPPGHHSMRSAANGFCVFNNVAIAAQYAKQKYG--VKRILIVDWDIHHGQGVQYCFEDDPSVLYFSWHRYEHQKFWPNLKDSDYDIVGKGEGAGFNINVPWNKVGMENSDYLSVFCHVLLPIAYEFCPDLVLVCAGFDSAIGDLEGEMCATPDIFAHLTYLLMNLAEGKLCAVLEGGYNLTSLAQSVCQTVQTLLGDPLPPLTNLTGPC-RSTLESLQCVRAAHRQHWSCLR 389
BLAST of Histone deacetylase,putative vs. Ensembl Medaka
Match: hdac7a (histone deacetylase 7 [Source:NCBI gene;Acc:101159670]) HSP 1 Score: 307.375 bits (786), Expect = 2.286e-88 Identity = 174/465 (37.42%), Postives = 263/465 (56.56%), Query Frame = 2
Query: 1280 QNCLKFLHFFWKSLSVNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKENDQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHM---NERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYV-----ESLGNICQESPTIYHLFEEEF-------------NSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKR---PVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGD--PLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLG----YPTNQIINFPINKSGIEAIRKTLEYQKPYWKCLKFY 2584
Q L+ LH K+L+V V + T +S L + + P LN E+ +K F T VYD +M H + S HPE R Q I+ L++ L +C+ + R A+ +E+ +H+ +V L + ++ + +F + ++I+ H+ ++ ++ G ++ + V +NGFA++RPPGHHA+ + P+GFC+FN+VAIAA K S + KILIVDWDVHHGNGTQ F+ +++VLYISLHRYD+G FFPGS GSP+ VG EGFNVN+AW P+ D+EY++AF ++VMPI+ EF+PD+V+VSAGFDAA G+ PLGG V+ +CFG +T L SLA G++ILALEGG++L I D CVS+LLG P + ++ P N + + +++ ++ Q +W+ +K +
Sbjct: 423 QKQLQQLHRQMKTLAVPVLPGGCSGGGGIHRPLSRTQSSPASTSLTLPEKP--------LNLAAPEISSKPRFT-----TGLVYDSQMLKHQCACGDNSSHPEHAGRIQSIWSRLQERGLRGQCESIRGRKATLEELQSVHTERHVLLYGTNPLNRLKLDNRKLAGIFSQRMFTMLPCGGVGVDNDTIWNESHTSTASRMAAGSVVELAFRVAKGELKNGFAVVRPPGHHADPSNPMGFCYFNSVAIAAKQLQQKLS--VSKILIVDWDVHHGNGTQEVFYNDRSVLYISLHRYDDGNFFPGS--GSPAEVGSGAGEGFNVNLAWTGGLDPPMGDAEYLAAFRSVVMPIAQEFSPDVVLVSAGFDAAEGNPAPLGGYKVSAKCFGFLTHQLMSLAGGRLILALEGGHDLTAICDASEACVSALLGMQDSMPEDVLLQKP-NANAVRSLQTVIQIQSQFWQNVKAH 869 HSP 2 Score: 242.662 bits (618), Expect = 3.271e-66 Identity = 136/383 (35.51%), Postives = 209/383 (54.57%), Query Frame = 2
Query: 263 TAFVYDEQMLLHS-NMWDNL-YFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQL------------------IEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLN---KTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIG--CPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTG--KAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVN 1330
T VYD QML H DN + E R++ + + E L C I+ ++ E + H++ HV L I + T + + +D ++ +++T AS ++AGS +E+ V KNGF ++RPPGHHA S GFC FN+V IAAK Q S KILIVDWDVHHGN TQ FYN VLYIS+HRY+DGNF+P + +G+ G G+N+N+ M +++YL+ F S+++PIA E++P++VL+SAGFD+A G P G V CF +TH+LM LA GR+++ LEGG+ + ++ D+ ++ L G + P+ +P + ++Q ++ FW+++ +
Sbjct: 489 TGLVYDSQMLKHQCACGDNSSHPEHAGRIQSIWSRLQERGLRGQCESIRGRKATLEELQSVHTERHVLLYGTNPLNRLKLDNRKLAGIFSQRMFTMLPCGGVGVDNDTIWNESHTSTASRMAAGSVVELAFRVAKGELKNGFAVVRPPGHHADPSNPMGFCYFNSVAIAAKQLQQKLSVSKILIVDWDVHHGNGTQEVFYNDRSVLYISLHRYDDGNFFPG--SGSPAEVGSGAGEGFNVNLAWTGGLDPPMGDAEYLAAFRSVVMPIAQEFSPDVVLVSAGFDAAEGNPAPLGGYKVSAKCFGFLTHQLMSLAGGRLILALEGGHDLTAICDASEACVSALLGMQDSMPEDVLLQKPNANAVRSLQTVIQIQSQFWQNVKAH 869
BLAST of Histone deacetylase,putative vs. Planmine SMEST
Match: SMESG000006246.1 (SMESG000006246.1) HSP 1 Score: 2098.94 bits (5437), Expect = 0.000e+0 Identity = 1011/1019 (99.21%), Postives = 1014/1019 (99.51%), Query Frame = 2
Query: 179 FGDEDLPAAQSNHGLYDNIELRINFPNKTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKENDQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMNERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINFPINKSGIEAIRKTLEYQKPYWKCLKFYEPLVVTYTEISPNQTNPAALDNIVQIDTNTLAESVRQLGIVEVTFQTEQSIEETLSQPRNDTFITEPNSSNPIIHLPPIVSSDNAVEVPATT-SINSTTHATQNISANFLSVDQSSGATPVSANVSRVINEGNSVGLVLQDIMNLSGVSNSDIHHFLGLTSNDPLPERVYAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQV 3232
FGDEDLPAAQSNHGLYDNIELRINFPNKTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLE FDEPCDSVKETIQNCLKFLHF+WKSLSVNVADNHEPYPEY+RHLPESTWNSSKVPKLPIEDNPNKCKE DQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMNERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGG DAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINFPINKSGIEAIRKTLEYQKPYWKCLKFYEPLVVTYTEISPNQTNPAALDNIVQI+TNTLAESVRQLGIVEVTFQTEQSIEETLSQPRNDTFITEPNSSNPIIHLPPIVSSDNAVEVP TT SINSTTHATQNISANFLSVDQSSGATPVSANVSRVINEGNSVGLVLQDIMNLSGVSNSDIHHFLGLTSNDPLPERVYAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQV
Sbjct: 24 FGDEDLPAAQSNHGLYDNIELRINFPNKTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLENFDEPCDSVKETIQNCLKFLHFYWKSLSVNVADNHEPYPEYMRHLPESTWNSSKVPKLPIEDNPNKCKEKDQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMNERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGVDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINFPINKSGIEAIRKTLEYQKPYWKCLKFYEPLVVTYTEISPNQTNPAALDNIVQIETNTLAESVRQLGIVEVTFQTEQSIEETLSQPRNDTFITEPNSSNPIIHLPPIVSSDNAVEVPPTTSSINSTTHATQNISANFLSVDQSSGATPVSANVSRVINEGNSVGLVLQDIMNLSGVSNSDIHHFLGLTSNDPLPERVYAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQV 1042
BLAST of Histone deacetylase,putative vs. Planmine SMEST
Match: SMESG000006246.1 (SMESG000006246.1) HSP 1 Score: 2098.55 bits (5436), Expect = 0.000e+0 Identity = 1011/1019 (99.21%), Postives = 1014/1019 (99.51%), Query Frame = 2
Query: 179 FGDEDLPAAQSNHGLYDNIELRINFPNKTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLEKFDEPCDSVKETIQNCLKFLHFFWKSLSVNVADNHEPYPEYLRHLPESTWNSSKVPKLPIEDNPNKCKENDQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMNERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINFPINKSGIEAIRKTLEYQKPYWKCLKFYEPLVVTYTEISPNQTNPAALDNIVQIDTNTLAESVRQLGIVEVTFQTEQSIEETLSQPRNDTFITEPNSSNPIIHLPPIVSSDNAVEVPATT-SINSTTHATQNISANFLSVDQSSGATPVSANVSRVINEGNSVGLVLQDIMNLSGVSNSDIHHFLGLTSNDPLPERVYAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQV 3232
FGDEDLPAAQSNHGLYDNIELRINFPNKTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLE FDEPCDSVKETIQNCLKFLHF+WKSLSVNVADNHEPYPEY+RHLPESTWNSSKVPKLPIEDNPNKCKE DQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMNERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGG DAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINFPINKSGIEAIRKTLEYQKPYWKCLKFYEPLVVTYTEISPNQTNPAALDNIVQI+TNTLAESVRQLGIVEVTFQTEQSIEETLSQPRNDTFITEPNSSNPIIHLPPIVSSDNAVEVP TT SINSTTHATQNISANFLSVDQSSGATPVSANVSRVINEGNSVGLVLQDIMNLSGVSNSDIHHFLGLTSNDPLPERVYAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQV
Sbjct: 26 FGDEDLPAAQSNHGLYDNIELRINFPNKTAFVYDEQMLLHSNMWDNLYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIEDTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPPKLENFDEPCDSVKETIQNCLKFLHFYWKSLSVNVADNHEPYPEYMRHLPESTWNSSKVPKLPIEDNPNKCKEKDQLNHKIYELRTKNAFNNYPNKTCFVYDCRMENHMNERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGVDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLGYPTNQIINFPINKSGIEAIRKTLEYQKPYWKCLKFYEPLVVTYTEISPNQTNPAALDNIVQIETNTLAESVRQLGIVEVTFQTEQSIEETLSQPRNDTFITEPNSSNPIIHLPPIVSSDNAVEVPPTTSSINSTTHATQNISANFLSVDQSSGATPVSANVSRVINEGNSVGLVLQDIMNLSGVSNSDIHHFLGLTSNDPLPERVYAVQPLLWCEHLNQVQQSPSANEIDVNASCTLCPSTRENWLCLTCYQV 1044
BLAST of Histone deacetylase,putative vs. Planmine SMEST
Match: SMESG000028609.1 (SMESG000028609.1) HSP 1 Score: 284.648 bits (727), Expect = 9.446e-80 Identity = 171/495 (34.55%), Postives = 265/495 (53.54%), Query Frame = 2
Query: 1505 YPNKTCFVYDCRMENHM---NERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLG----NICQESPTIYHLFEEEF------------NSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRP------VRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAAR--GDPLGGLTVTPECFGNMTQML--TSLANGKVILALEGGYNLNVISDCMSHCVSSL----------------------LGYPTNQIINFPINKSGIEAIRKTLEYQKPYWKCLKFYEPLVVTYTEISPNQTNPAALDNIVQIDTNTLAESVRQLGIVEVTFQTEQSIEETLSQPRNDTFITEPNSSNPIIHLPPIVSSDN 2836
YPN T VYD M +H IHPES RR M++E L+++ ++ RC ++ + AS D++ L H Y G N + +P + L EF ++I+ N H+ +A L+ G ++ + ++ NGFA++RPPGHHAE + +GF +FN+VAIAA + ++K++LI+DWD+HHGNGTQ F+ + +VLYISLHR+DNG FFPG+ G +G +N+NIAW P + D+EYI+AF++IV+P++ EFNPDL+IVSAGFDA + LGG +V+P CFG MTQ L + LA G+V++ALEGGY++ + DC+ C+ +L + P++++ P + + IE + + K W+C +F + Y + D + ++ + +S+ L + E+T Q E S E P+ +PIIH P+ N
Sbjct: 567 YPNTTAIVYDVGMLSHRCLCGNEDIHPESSRRLAMVWERLKESQIVLRCHVIQGKKASMDDLQLCHEDTYSVLFGTNPANRLKINPQL--LMSVEFCRLPCGGIGVDSDTIWNNAHTANAARLAVGCVVELTLKIVRGELRNGFALVRPPGHHAEFSQAMGFGYFNSVAIAAKKITMQ--TAVKRVLIIDWDIHHGNGTQQIFYNDPSVLYISLHRHDNGHFFPGT--GLIEEIGEGAGTNYNINIAWKSPPDGSFLSMSDAEYIAAFVHIVLPVAKEFNPDLIIVSAGFDATKMHSSSLGGYSVSPACFGWMTQKLVMSGLAEGRVVMALEGGYDIASLCDCVEVCMRALIKPDVLNFTESGTRPLKDAEGKMTIPSSELNRVPCDIA-IETLFTVSQTHKKKWQCFRFLTKESIKY----------SYNDLVKKLLGSKSYDSIPLLAMSELTVQHEHSKHE----PKQVIDYEMICVKSPIIHSEPMEQESN 1040 HSP 2 Score: 220.32 bits (560), Expect = 1.933e-58 Identity = 125/349 (35.82%), Postives = 196/349 (56.16%), Query Frame = 2
Query: 245 INFPNKTAFVYDEQMLLHSNMWDN--LYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHV---------QLIEDTQTMTAIQLKEL-----SSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKT------NMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAI--GCPEGSMDVHPACFAHMTHKLM--DLARGRVVVLLEGGYCMESLKDSVVLTLATL 1213
+ +PN TA VYD ML H + N ++ E RL + +E + E+ ++ C IQ K+ + + H ++ +L + Q + +++ L D ++ + +T A+ ++ G +E+ ++ +NGF L+RPPGHHA S+A GF FN+V IAAK + + +++LI+DWD+HHGN TQ FYN VLYIS+HR+++G+F+P + IG G YNINI +M++++Y++ F I+LP+A E+NP+L+++SAGFD+ G V PACF MT KL+ LA GRVV+ LEGGY + SL D V + + L
Sbjct: 565 LEYPNTTAIVYDVGMLSHRCLCGNEDIHPESSRRLAMVWERLKESQIVLRCHVIQGKKASMDDLQLCHEDTYSVLFGTNPANRLKINPQLLMSVEFCRLPCGGIGVDSDTIWNNAHTANAARLAVGCVVELTLKIVRGELRNGFALVRPPGHHAEFSQAMGFGYFNSVAIAAKKITMQTAVKRVLIIDWDIHHGNGTQQIFYNDPSVLYISLHRHDNGHFFPG--TGLIEEIGEGAGTNYNINIAWKSPPDGSFLSMSDAEYIAAFVHIVLPVAKEFNPDLIIVSAGFDATKMHSSSLGGYSVSPACFGWMTQKLVMSGLAEGRVVMALEGGYDIASLCDCVEVCMRAL 911
BLAST of Histone deacetylase,putative vs. Planmine SMEST
Match: SMESG000028609.1 (SMESG000028609.1) HSP 1 Score: 284.263 bits (726), Expect = 2.278e-79 Identity = 171/495 (34.55%), Postives = 265/495 (53.54%), Query Frame = 2
Query: 1505 YPNKTCFVYDCRMENHM---NERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLG----NICQESPTIYHLFEEEF------------NSIYINQHSYISALLSCGLLLNVIDEVCSDRSENGFAIIRPPGHHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRP------VRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAAR--GDPLGGLTVTPECFGNMTQML--TSLANGKVILALEGGYNLNVISDCMSHCVSSL----------------------LGYPTNQIINFPINKSGIEAIRKTLEYQKPYWKCLKFYEPLVVTYTEISPNQTNPAALDNIVQIDTNTLAESVRQLGIVEVTFQTEQSIEETLSQPRNDTFITEPNSSNPIIHLPPIVSSDN 2836
YPN T VYD M +H IHPES RR M++E L+++ ++ RC ++ + AS D++ L H Y G N + +P + L EF ++I+ N H+ +A L+ G ++ + ++ NGFA++RPPGHHAE + +GF +FN+VAIAA + ++K++LI+DWD+HHGNGTQ F+ + +VLYISLHR+DNG FFPG+ G +G +N+NIAW P + D+EYI+AF++IV+P++ EFNPDL+IVSAGFDA + LGG +V+P CFG MTQ L + LA G+V++ALEGGY++ + DC+ C+ +L + P++++ P + + IE + + K W+C +F + Y + D + ++ + +S+ L + E+T Q E S E P+ +PIIH P+ N
Sbjct: 616 YPNTTAIVYDVGMLSHRCLCGNEDIHPESSRRLAMVWERLKESQIVLRCHVIQGKKASMDDLQLCHEDTYSVLFGTNPANRLKINPQL--LMSVEFCRLPCGGIGVDSDTIWNNAHTANAARLAVGCVVELTLKIVRGELRNGFALVRPPGHHAEFSQAMGFGYFNSVAIAAKKITMQ--TAVKRVLIIDWDIHHGNGTQQIFYNDPSVLYISLHRHDNGHFFPGT--GLIEEIGEGAGTNYNINIAWKSPPDGSFLSMSDAEYIAAFVHIVLPVAKEFNPDLIIVSAGFDATKMHSSSLGGYSVSPACFGWMTQKLVMSGLAEGRVVMALEGGYDIASLCDCVEVCMRALIKPDVLNFTESGTRPLKDAEGKMTIPSSELNRVPCDIA-IETLFTVSQTHKKKWQCFRFLTKESIKY----------SYNDLVKKLLGSKSYDSIPLLAMSELTVQHEHSKHE----PKQVIDYEMICVKSPIIHSEPMEQESN 1089 HSP 2 Score: 219.935 bits (559), Expect = 3.200e-58 Identity = 125/349 (35.82%), Postives = 195/349 (55.87%), Query Frame = 2
Query: 245 INFPNKTAFVYDEQMLLHSNMWDN--LYFERPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIE---------DTQTMTAIQLKEL-----SSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPGHHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKT------NMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDSAI--GCPEGSMDVHPACFAHMTHKLM--DLARGRVVVLLEGGYCMESLKDSVVLTLATL 1213
+ +PN TA VYD ML H + N ++ E RL + +E + E+ ++ C IQ K+ + + H ++ L + Q + +++ L D ++ + +T A+ ++ G +E+ ++ +NGF L+RPPGHHA S+A GF FN+V IAAK + + +++LI+DWD+HHGN TQ FYN VLYIS+HR+++G+F+P + IG G YNINI +M++++Y++ F I+LP+A E+NP+L+++SAGFD+ G V PACF MT KL+ LA GRVV+ LEGGY + SL D V + + L
Sbjct: 614 LEYPNTTAIVYDVGMLSHRCLCGNEDIHPESSRRLAMVWERLKESQIVLRCHVIQGKKASMDDLQLCHEDTYSVLFGTNPANRLKINPQLLMSVEFCRLPCGGIGVDSDTIWNNAHTANAARLAVGCVVELTLKIVRGELRNGFALVRPPGHHAEFSQAMGFGYFNSVAIAAKKITMQTAVKRVLIIDWDIHHGNGTQQIFYNDPSVLYISLHRHDNGHFFPG--TGLIEEIGEGAGTNYNINIAWKSPPDGSFLSMSDAEYIAAFVHIVLPVAKEFNPDLIIVSAGFDATKMHSSSLGGYSVSPACFGWMTQKLVMSGLAEGRVVMALEGGYDIASLCDCVEVCMRAL 960
BLAST of Histone deacetylase,putative vs. Planmine SMEST
Match: SMESG000060876.1 (SMESG000060876.1) HSP 1 Score: 112.849 bits (281), Expect = 8.763e-26 Identity = 82/326 (25.15%), Postives = 150/326 (46.01%), Query Frame = 2
Query: 1514 KTCFVYDCRMENHMNERSIHPESPRRTQMIFEFLRDNSLLSRCKQLESRLASKDEIGLIHSPNYVESLGNICQESPTIYHLFEEEFNSIYINQHSYISALLSCGLLLNVIDEVCS----DRSENGFAIIRPPG-HHAEVNYPLGFCFFNNVAIAANYALTKYSESIKKILIVDWDVHHGNGTQHQFWTNKNVLYISLHRYDNGLFFPGSTDGSPSAVGGDDAEGFNVNIAWNKRPVRDSEYISAFINIVMPISHEFNPDLVIVSAGFDAARGDPLGGLTVTPECFGNMTQMLTSLANGKVILALEGGYNLNVISDCMSHCVSSLLG 2476
K C+ YD + N+ + HP P R +M L + L + + + A+ D++ + H+ Y++ L I P H + +E + + + L L+ V S ++++ AI G HHA+ + GFC+ N++ + L KY E ++L VD D+HHG+G + F+T V+ +S H+Y G +FPG+ G +G + + VN + + D Y S F +V + F P+ +++ G D+ GD LG ++ + G + + ++L GGY + ++ C ++ + LG
Sbjct: 8 KVCYYYDGDIGNYYYGQG-HPMKPHRIRMTHNLLLNYGLYRKMEVYKPSKATADDMTMFHTDEYIQFLQRI---HPDNMHEYNKEMQRFNVGEDCPVFDGLFEFCQLSAGGSVASAVKLNKNKADIAINWSGGLHHAKKSEASGFCYVNDIVMGI-LELLKYHE---RVLYVDIDIHHGDGVEEAFYTTDRVMTVSFHKY--GEYFPGT--GDIKDIGAGKGKNYAVNFPL-RDGIDDESYESIFKPVVEKVIESFKPNAIVLQCGADSLSGDRLGCFNLSLKGHGKCVEYMRQQPIPLLMLG-GGGYTIRNVARCWTYETALALG 319 HSP 2 Score: 103.99 bits (258), Expect = 7.974e-23 Identity = 77/310 (24.84%), Postives = 140/310 (45.16%), Query Frame = 2
Query: 329 RPDRLRVCYEGICETNLLEDCIRIQAKEIDNELIYYSHSQSHVQLIE----DTQTMTAIQLKELSSQHDCVFFDNNTKLASFISAGSTIEVLKAVLDDRAKNGFCLIRPPG-HHAMESEASGFCIFNNVGIAAKYAQLNYSTQKILIVDWDVHHGNATQYQFYNTSKVLYISIHRYEDGNFWPKLRESNYDYIGANEGRGYNINIPLNKTNMTNSDYLSIFHSIILPIAYEYNPELVLISAGFDS----AIGCPEGSMDVHPACFAHMTHKLMDLARGRVVVLLEGGYCMESLKDSVVLTLATLTGKAPP 1231
+P R+R+ + + L + + + + H+ ++Q ++ D +++ + DC FD + + GS V AV ++ K + G HHA +SEASGFC N++ + L Y +++L VD D+HHG+ + FY T +V+ +S H+Y G ++P + IGA +G+ Y +N PL + + + Y SIF ++ + + P +++ G DS +GC S+ H C +M + + L ++L GGY + ++ A G P
Sbjct: 29 KPHRIRMTHNLLLNYGLYRKMEVYKPSKATADDMTMFHTDEYIQFLQRIHPDNMHEYNKEMQRFNVGEDCPVFDGLFEFCQLSAGGS---VASAVKLNKNKADIAINWSGGLHHAKKSEASGFCYVNDI-VMGILELLKYH-ERVLYVDIDIHHGDGVEEAFYTTDRVMTVSFHKY--GEYFPGT--GDIKDIGAGKGKNYAVNFPL-RDGIDDESYESIFKPVVEKVIESFKPNAIVLQCGADSLSGDRLGCFNLSLKGHGKCVEYMRQQPIPL-----LMLGGGGYTIRNVARCWTYETALALGTTIP 323 The following BLAST results are available for this feature:
BLAST of Histone deacetylase,putative vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Histone deacetylase,putative vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Histone deacetylase,putative vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Histone deacetylase,putative vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Histone deacetylase,putative vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Histone deacetylase,putative vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Histone deacetylase,putative vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Histone deacetylase,putative vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Histone deacetylase,putative vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Histone deacetylase,putative vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Histone deacetylase,putative vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of Histone deacetylase,putative vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Histone deacetylase,putative vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Histone deacetylase,putative vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30019300 ID=SMED30019300|Name=Histone deacetylase,putative|organism=Schmidtea mediterranea sexual|type=transcript|length=3598bpback to top protein sequence of SMED30019300-orf-1 >SMED30019300-orf-1 ID=SMED30019300-orf-1|Name=SMED30019300-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1109bp MSQSSPRSLRSQVLRRRRRSRSNSPFGDEDLPAAQSNHGLYDNIELRINFback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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