Roundabout, axon guidance receptor, homolog 2 (Drosophila)

Overview


Name	Roundabout, axon guidance receptor, homolog 2 (Drosophila)
Smed ID	SMED30019296
Length (bp)	851

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Roundabout, axon guidance receptor, homolog 2 (Drosophila) (SMED30019296) t-SNE clustered cells

Violin plots show distribution of expression levels for Roundabout, axon guidance receptor, homolog 2 (Drosophila) (SMED30019296) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Roundabout, axon guidance receptor, homolog 2 (Drosophila) (SMED30019296) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30019296

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 10

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
gut	SMED30019296	h1SMcG0000204	Contig4707	newmark_ests	PMID:23079596 Forsthoefel et al., 2012
intestinal phagocyte	SMED30019296	h1SMcG0000204	Contig4707	newmark_ests	PMID:23079596 Forsthoefel et al., 2012
gut	SMED30019296	h1SMcG0006295	Contig4707	newmark_ests	PMID:23079596 Forsthoefel et al., 2012
intestinal phagocyte	SMED30019296	h1SMcG0006295	Contig4707	newmark_ests	PMID:23079596 Forsthoefel et al., 2012
head region	SMED30019296	h1SMcG0006295	SmedASXL_010629	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
head region	SMED30019296	h1SMcG0006295	SmedASXL_015715	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
muscle cell	SMED30019296	h1SMcG0006295	dd_Smed_v4_14150_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
anterior side	SMED30019296	h1SMcG0006295	dd_Smed_v4_14150_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
head region	SMED30019296	h1SMcG0006295	dd_Smed_v6_19912_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
head region	SMED30019296	h1SMcG0006295	dd_Smed_v6_14150_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Human
Match: PXDN (peroxidasin [Source:HGNC Symbol;Acc:HGNC:14966])

HSP 1 Score: 73.559 bits (179), Expect = 4.583e-14
Identity = 60/195 (30.77%), Postives = 89/195 (45.64%), Query Frame = 1

Query:  154 RITRLSDDYFPRSG-SLKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKTGLSYLS----PTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEYFHLKSSA 723
            RIT    D    SG ++   C AEGNP P I W     +  M+ D  ++L  D   G L+I N Q      + C A N    + ++ V   L Y      PT+ IQP++ ++L   +SV L C    G+PPP+  W +  R  L      DP+  I  +       + I+++   DSGEY C A N    + ++A
Sbjct:  243 RITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDD---GTLMIQNTQETDQGIYQCMAKNVAGEVKTQEVT--LRYFGSPARPTFVIQPQNTEVLVG-ESVTLECSA-TGHPPPRISWTRGDRTPLPV----DPRVNITPSG-----GLYIQNVVQGDSGEYACSATNNIDSVHATA 421

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Human
Match: PXDN (peroxidasin [Source:HGNC Symbol;Acc:HGNC:14966])

HSP 1 Score: 73.559 bits (179), Expect = 5.673e-14
Identity = 63/198 (31.82%), Postives = 90/198 (45.45%), Query Frame = 1

Query:  154 RITRLSDDYFPRSG-SLKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKT---GLSYLS----PTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEYFHLKSSA 723
            RIT    D    SG ++   C AEGNP P I W     +  M+ D  ++L  D   G L+I N Q      + C A N     V+  VKT    L Y      PT+ IQP++ ++L   +SV L C    G+PPP+  W +  R  L      DP+  I  +       + I+++   DSGEY C A N    + ++A
Sbjct:  247 RITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDD---GTLMIQNTQETDQGIYQCMAKN-----VAGEVKTQEVTLRYFGSPARPTFVIQPQNTEVLVG-ESVTLECS-ATGHPPPRISWTRGDRTPLPV----DPRVNITPSG-----GLYIQNVVQGDSGEYACSATNNIDSVHATA 425

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Human
Match: CNTN4 (contactin 4 [Source:HGNC Symbol;Acc:HGNC:2174])

HSP 1 Score: 65.855 bits (159), Expect = 4.876e-12
Identity = 52/169 (30.77%), Postives = 77/169 (45.56%), Query Frame = 1

Query:  199 LKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNP---QPKITYEFYCNASNDKTWIVSKSVKTGLSYLSPTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANN 696
            +KL C  +GNP P I W    T      D  MD +    +G L+I+NP   Q   TY+  C A+N    IVS+  K   +YL   +K +  S   ++  Q ++L C      PPP +          +Y    D +RF+  + E GN  + I  ++ SD G Y C+  N
Sbjct:   46 VKLNCEVKGNPKPHIRWKLNGT----DVDTGMDFRYSVVEGSLLINNPNKTQDAGTYQ--CTATNSFGTIVSREAKLQFAYLD-NFKTRTRSTVSVRRGQGMVLLC-----GPPPHSGELSYAWIFNEYPSYQDNRRFV--SQETGN--LYIAKVEKSDVGNYTCVVTN 198

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Human
Match: HMCN1 (hemicentin 1 [Source:HGNC Symbol;Acc:HGNC:19194])

HSP 1 Score: 67.0106 bits (162), Expect = 1.043e-11
Identity = 46/167 (27.54%), Postives = 74/167 (44.31%), Query Frame = 1

Query:  196 SLKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKTGLSYLSPTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANN 696
            ++ L C  +G P PTI W       +     ++   +    G L I N        + C A N    I S++  T    ++P   I P    ++ E Q + L C L  GNP P+ +W K+   LL+     +P   + S+      S+ I+ ++L D GEY C+A+N
Sbjct:  809 NVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVI-EGQQLTLPCTLLAGNPIPERRWIKNSAMLLQ-----NPYITVRSDG-----SLHIERVQLQDGGEYTCVASN 964

HSP 2 Score: 59.6918 bits (143), Expect = 2.829e-9
Identity = 53/187 (28.34%), Postives = 83/187 (44.39%), Query Frame = 1

Query:  199 LKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNAS-----NDKTWIVSKSVKTGLSYLSPTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEYFHLKSSASWVLVMN 744
            L+L C+A G P P +TW     + L Q D    L       +L IS  Q + T  + C AS     +DK ++V   V   ++        +P  I +L+  Q V L C+  D  PPP   W ++   L     Q  P+  I S   +    +QI +  L D+  Y C+A+N     K++  ++L +N
Sbjct: 3546 LELTCIASGIPAPKMTWM-KDGRPLPQTDQVQTLGGGE---VLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTD-----EPRDITVLRNRQ-VTLECK-SDAVPPPVITWLRNGERL-----QATPRVRILSGGRY----LQINNADLGDTANYTCVASN--IAGKTTREFILTVN 3710

HSP 3 Score: 58.151 bits (139), Expect = 7.611e-9
Identity = 54/183 (29.51%), Postives = 88/183 (48.09%), Query Frame = 1

Query:  196 SLKLICVAEGNPMPTITW-HDTKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYEFYC---NASNDKTWIVSKSVKTGLSYLSPTYKIQPESIQ--ILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEYFHLKSSAS 726
            S+ L C A G P+P+ITW  D    SL     +  ++  S   +L +     +   ++ C   NA+ ++  I       GLS L P + +   +++   +KE QSV L+C++  GNP P+  W KD + L     Q+D    I S    G   +QI ++++  +G Y CLA++   H   S S
Sbjct: 2403 SVSLTCEASGIPLPSITWFKDGWPVSL-----SNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIF------GLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEV-TGNPVPEITWHKDGQPL-----QEDEAHHIIS----GGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFS 2564

HSP 4 Score: 53.9138 bits (128), Expect = 1.866e-7
Identity = 52/214 (24.30%), Postives = 88/214 (41.12%), Query Frame = 1

Query:  181 FPRSGSLKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKTGLSYLSPTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEYFHLKSSASWVLVMNSFSDLIFDISIKQISQKTGDDVEMLC 822
            F     + ++C A G P P I W  T     +       + +D   G L I N  PK    + C ASN      +    + L Y+     +  +S  ++      ++ C+   G PPP+ KWFK   EL        P  F+  +   G   ++I+  +  D+G+Y C+A NE       A+  + ++  S  +F      +S + G +V + C
Sbjct:  623 FTGGSEVSIMCSATGYPKPKIAW--TVNDMFIVGSHRYRMTSD---GTLFIKNAAPKDAGIYGCLASNSAG---TDKQNSTLRYIEAPKLMVVQSELLVALGDITVMECK-TSGIPPPQVKWFKGDLEL-------RPSTFLIIDPLLG--LLKIQETQDLDAGDYTCVAINE----AGRATGKITLDVGSPPVFIQEPADVSMEIGSNVTLPC 814

HSP 5 Score: 52.373 bits (124), Expect = 5.589e-7
Identity = 55/199 (27.64%), Postives = 87/199 (43.72%), Query Frame = 1

Query:  199 LKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKTGLSYLSPTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEYFHLKSSASW-VLVMNSFSDLIFDISIKQISQ 792
            + L C A+G P P ITWH    +++++      L + S Q    I+  QP     + C A+N      S S  T L+   P      E    + E    IL C + DG P P   W KD   L     +       ++   +G   + ++++ L DSG Y C+ANN       + S  V V+ +F++L  D+S+ +  Q
Sbjct: 4096 ITLSCEADGLPPPDITWH-KDGRAIVESIRQRVLSSGSLQ----IAFVQPGDAGHYTCMAANVAG---SSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPC-VADGIPTPAINWKKDNVLLANLLGK-------YTAEPYG--ELILENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQ 4276

HSP 6 Score: 50.8322 bits (120), Expect = 2.070e-6
Identity = 54/192 (28.12%), Postives = 80/192 (41.67%), Query Frame = 1

Query:  145 HTIRITRLSDDYFPRSGSLKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKTGLS-YLSPTY-----KIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQREL-LKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNE 699
            H +    L D       S+ L C   GNP+P ITWH  K    +Q D+A  + +      L I+N Q   T  + C AS+       KS    L+ ++SPT         PE + ++       L C+     PP    WFKD   L    +I+  P          G  ++QI + +  ++G Y C+A NE
Sbjct: 2479 HIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWH--KDGQPLQEDEAHHIISGGR--FLQITNVQVPHTGRYTCLASSPAG---HKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILN-SPTSLVCE-AYSYPPATITWFKDGTPLESNRNIRILP----------GGRTLQILNAQEDNAGRYSCVATNE 2651

HSP 7 Score: 50.447 bits (119), Expect = 2.659e-6
Identity = 46/174 (26.44%), Postives = 75/174 (43.10%), Query Frame = 1

Query:  199 LKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKTGLSYLSPTY--------KIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANN 696
            + L C A GNP P++ W  +K   L+    A    +    G L + +P  + + E+ C A+N   +   K   T   Y+ P          + +P  I +L   + V L C++    PPP   W K+ + +  +S    P+     +      SM+I   + SDSG Y C+A N
Sbjct:  998 VTLPCKASGNPKPSVIW--SKKGELISTSSAK--FSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLT--VYVRPRVFGDQRGLSQDKPVEISVLAG-EEVTLPCEV-KSLPPPIITWAKETQLISPFS----PRHTFLPSG-----SMKITETRTSDSGMYLCVATN 1154

HSP 8 Score: 48.9062 bits (115), Expect = 7.769e-6
Identity = 52/215 (24.19%), Postives = 91/215 (42.33%), Query Frame = 1

Query:  196 SLKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASN-----DKTWIVSKSVKTGLSYLSPTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEYFHLKSSASWVLVMNSFSDLIFDISIKQISQKTGDDVEMLCD 825
            S+ L C +   P P ITW+  K   ++     +++  D +  +L I   +   T ++ C A N     DK + ++  V   +    P  ++  E+I        V L+C    G PPP   W K+ + +      D  +  I S    G   +QI   + SDSG Y C+A+N     K+   + L +     +        +S   G++VE++C+
Sbjct: 3076 SVSLECESNAVPPPVITWY--KNGRMITESTHVEILADGQ--MLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIE--GPEREVIVETIS-----NPVTLTCD-ATGIPPPTIAWLKNHKRIEN---SDSLEVRILS----GGSKLQIARSQHSDSGNYTCIASN--MEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCN 3269

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Human
Match: CNTN4 (contactin 4 [Source:HGNC Symbol;Acc:HGNC:2174])

HSP 1 Score: 66.2402 bits (160), Expect = 1.611e-11
Identity = 52/169 (30.77%), Postives = 77/169 (45.56%), Query Frame = 1

Query:  199 LKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNP---QPKITYEFYCNASNDKTWIVSKSVKTGLSYLSPTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANN 696
            +KL C  +GNP P I W    T      D  MD +    +G L+I+NP   Q   TY+  C A+N    IVS+  K   +YL   +K +  S   ++  Q ++L C      PPP +          +Y    D +RF+  + E GN  + I  ++ SD G Y C+  N
Sbjct:   46 VKLNCEVKGNPKPHIRWKLNGT----DVDTGMDFRYSVVEGSLLINNPNKTQDAGTYQ--CTATNSFGTIVSREAKLQFAYLD-NFKTRTRSTVSVRRGQGMVLLC-----GPPPHSGELSYAWIFNEYPSYQDNRRFV--SQETGN--LYIAKVEKSDVGNYTCVVTN 198

HSP 2 Score: 63.929 bits (154), Expect = 7.814e-11
Identity = 65/223 (29.15%), Postives = 101/223 (45.29%), Query Frame = 1

Query:  187 RSGSLKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKTGLSYLSPTYKIQPESIQILKEF-----QSVILSCQLPDGNPPPKTKWFKDQRELL-KYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEYFHLKSSA--SWVLVMNSFSDLIFDISIKQISQ-KTGDDVEMLCDP 828
            +  ++KL C A GNP+PTI W     K +     A   +     G+L I N Q +    + C A N +     K+V  G      T+  QP  IQ + +      ++V   C+  +G P P  KW K+   LL +  IQ           E G  ++ I  + LSD+G Y CLA N++  + S+A  S + V   FS  +    +K+++  K G +V + C P
Sbjct:  239 KGATVKLECFALGNPVPTIIWRRADGKPI-----ARKARRHKSNGILEIPNFQQEDAGLYECVAENSR----GKNVARG----QLTFYAQPNWIQKINDIHVAMEENVFWECK-ANGRPKPTYKWLKNGEPLLTRDRIQI----------EQGTLNITI--VNLSDAGMYQCLAENKHGVIFSNAELSVIAVGPDFSRTL----LKRVTLVKVGGEVVIECKP 431

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Celegans
Match: sax-3 (pep chromosome:WBcel235:X:3451945:3465925:-1 gene:WBGene00004729.1 transcript:ZK377.2a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:sax-3)

HSP 1 Score: 65.4698 bits (158), Expect = 1.002e-11
Identity = 49/179 (27.37%), Postives = 77/179 (43.02%), Query Frame = 1

Query:  208 ICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQ----------GLLII------SNPQPKITYEFYCNASNDKTWIVSKSVKTGLSYLSPTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANN 696
            + V+ G+P          T  +  Y D   + T+ EQ          G L +       N +      +YC ASN+   + S      L+ L   ++++P ++Q L   +  +L C  P G P P   W KD +EL    IQD P+  +     H + ++ I  +  SDSG Y C+ANN
Sbjct:   40 VVVSRGSPATLNCGAKPSTAKITWYKDGQPVITNKEQVNSHRIVLDTGSLFLLKVNSGKNGKDSDAGAYYCVASNEHGEVKSNEGSLKLAMLREDFRVRPRTVQALGG-EMAVLECSPPRGFPEPVVSWRKDDKEL---RIQDMPRYTL-----HSDGNLIIDPVDRSDSGTYQCVANN 209

HSP 2 Score: 49.6766 bits (117), Expect = 1.594e-6
Identity = 51/190 (26.84%), Postives = 68/190 (35.79%), Query Frame = 1

Query:  160 TRLSDDYFPRSGSLKLICVAEGNPMPTITWHDTKTKSLM--QYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSV-------KTGLSYLSPTYKIQ-PESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNE 699
            T+ +D   P  G+    C   G P P   W     + L+   Y  A      S  G L I   +      + C   N     +SK+         TG +   P   I+     Q L    S IL CQ   G P P   W +D    L   I D         ++H   S+ I  LK  D+G Y C+A NE
Sbjct:  321 TKPADQSVPAGGTATFECTLVGQPSPAYFWSKEGQQDLLFPSYVSADGRTKVSPTGTLTIEEVRQVDEGAYVCAGMNSAGSSLSKAALKVTTKAVTGNTPAKPPPTIEHGHQNQTLMVGSSAILPCQ-ASGKPTPGISWLRDG---LPIDITDS------RISQHSTGSLHIADLKKPDTGVYTCIAKNE 500

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Celegans
Match: sax-3 (pep chromosome:WBcel235:X:3451945:3465925:-1 gene:WBGene00004729.1 transcript:ZK377.2b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:sax-3)

HSP 1 Score: 65.4698 bits (158), Expect = 1.050e-11
Identity = 49/179 (27.37%), Postives = 77/179 (43.02%), Query Frame = 1

Query:  208 ICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQ----------GLLII------SNPQPKITYEFYCNASNDKTWIVSKSVKTGLSYLSPTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANN 696
            + V+ G+P          T  +  Y D   + T+ EQ          G L +       N +      +YC ASN+   + S      L+ L   ++++P ++Q L   +  +L C  P G P P   W KD +EL    IQD P+  +     H + ++ I  +  SDSG Y C+ANN
Sbjct:   40 VVVSRGSPATLNCGAKPSTAKITWYKDGQPVITNKEQVNSHRIVLDTGSLFLLKVNSGKNGKDSDAGAYYCVASNEHGEVKSNEGSLKLAMLREDFRVRPRTVQALGG-EMAVLECSPPRGFPEPVVSWRKDDKEL---RIQDMPRYTL-----HSDGNLIIDPVDRSDSGTYQCVANN 209

HSP 2 Score: 49.6766 bits (117), Expect = 1.609e-6
Identity = 51/190 (26.84%), Postives = 68/190 (35.79%), Query Frame = 1

Query:  160 TRLSDDYFPRSGSLKLICVAEGNPMPTITWHDTKTKSLM--QYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSV-------KTGLSYLSPTYKIQ-PESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNE 699
            T+ +D   P  G+    C   G P P   W     + L+   Y  A      S  G L I   +      + C   N     +SK+         TG +   P   I+     Q L    S IL CQ   G P P   W +D    L   I D         ++H   S+ I  LK  D+G Y C+A NE
Sbjct:  321 TKPADQSVPAGGTATFECTLVGQPSPAYFWSKEGQQDLLFPSYVSADGRTKVSPTGTLTIEEVRQVDEGAYVCAGMNSAGSSLSKAALKVTTKAVTGNTPAKPPPTIEHGHQNQTLMVGSSAILPCQ-ASGKPTPGISWLRDG---LPIDITDS------RISQHSTGSLHIADLKKPDTGVYTCIAKNE 500

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Celegans
Match: unc-89 (Muscle M-line assembly protein unc-89 [Source:UniProtKB/Swiss-Prot;Acc:O01761])

HSP 1 Score: 58.9214 bits (141), Expect = 1.939e-9
Identity = 49/193 (25.39%), Postives = 90/193 (46.63%), Query Frame = 1

Query:  157 ITRLSDDYFPRSGSLKLICVAEGNPMPTITW-HDTKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYE--FYCNASNDKTWIVSK---SVKTGLSYLSPTYKIQPESIQILK-----EFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEY 702
            I  L D     S  + L C   G P P ++W HD KT +         +  +S +G+  ++    +++++  + C A N +    ++   +V+   S  + T +  PE +++L+     E Q  IL C++  G P PK KW K+ +E+      +   R    + + G  ++   ++  +D+GEY C A NEY
Sbjct: 2524 IVALQDKTTKTSEKVVLECKVIGEPKPKVSWLHDNKTIT------QESITVESVEGVERVTITSSELSHQGKYTCIAENTEGTSKTEAFLTVQDTASSKTDTGRGAPEFVELLRSCTVTEKQQAILKCKV-KGEPRPKIKWTKEGKEV------EMSARVRAEHKDDGTLTLTFDNVTQADAGEYRCEAENEY 2703

HSP 2 Score: 48.1358 bits (113), Expect = 5.551e-6
Identity = 43/173 (24.86%), Postives = 68/173 (39.31%), Query Frame = 1

Query:  205 LICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASND--KTW-----IVSKSVKTGLSYLSPTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEY 702
            L C  +G P P I W     +  M      + K D     L   N       E+ C A N+    W     IV+      +   +P + +QP    ++   ++ +L  ++  G P P  KW+K+  EL          R    N + G   + + + KL D  EY C A+NE+
Sbjct: 2643 LKCKVKGEPRPKIKWTKEGKEVEMSARVRAEHKDDGTL-TLTFDNVTQADAGEYRCEAENEYGSAWTEGPIIVTLEGAPKIDGEAPDF-LQPVKPAVVTVGETAVLEGKI-SGKPKPSVKWYKNGEEL------KPSDRVKIENLDDGTQRLTVTNAKLDDMDEYRCEASNEF 2806

HSP 3 Score: 47.3654 bits (111), Expect = 8.898e-6
Identity = 30/109 (27.52%), Postives = 52/109 (47.71%), Query Frame = 1

Query:  505 CQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEYFHLKSSASW--VLVMNSFSDLIFDISIKQISQKTGDDVEMLCD 825
            C    G P P   W+KD  +L       + +R  F ++E G  +M I  ++++D+G Y C+A NEY    +SA +  + V    +   F   ++    K GD ++  C+
Sbjct:   95 CLKVTGYPLPDITWYKDDVQL------HEDERHTFYSDEDGFFAMTIDPVQVTDTGRYTCMATNEYGQASTSAFFRVLKVEKEAAPPAFVTKLRDKECKEGDVIDFECE 197

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Celegans
Match: unc-89 (Muscle M-line assembly protein unc-89 [Source:UniProtKB/Swiss-Prot;Acc:O01761])

HSP 1 Score: 58.5362 bits (140), Expect = 2.336e-9
Identity = 49/193 (25.39%), Postives = 90/193 (46.63%), Query Frame = 1

Query:  157 ITRLSDDYFPRSGSLKLICVAEGNPMPTITW-HDTKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYE--FYCNASNDKTWIVSK---SVKTGLSYLSPTYKIQPESIQILK-----EFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEY 702
            I  L D     S  + L C   G P P ++W HD KT +         +  +S +G+  ++    +++++  + C A N +    ++   +V+   S  + T +  PE +++L+     E Q  IL C++  G P PK KW K+ +E+      +   R    + + G  ++   ++  +D+GEY C A NEY
Sbjct: 2997 IVALQDKTTKTSEKVVLECKVIGEPKPKVSWLHDNKTIT------QESITVESVEGVERVTITSSELSHQGKYTCIAENTEGTSKTEAFLTVQDTASSKTDTGRGAPEFVELLRSCTVTEKQQAILKCKV-KGEPRPKIKWTKEGKEV------EMSARVRAEHKDDGTLTLTFDNVTQADAGEYRCEAENEY 3176

HSP 2 Score: 47.7506 bits (112), Expect = 6.669e-6
Identity = 43/173 (24.86%), Postives = 68/173 (39.31%), Query Frame = 1

Query:  205 LICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASND--KTW-----IVSKSVKTGLSYLSPTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEY 702
            L C  +G P P I W     +  M      + K D     L   N       E+ C A N+    W     IV+      +   +P + +QP    ++   ++ +L  ++  G P P  KW+K+  EL          R    N + G   + + + KL D  EY C A+NE+
Sbjct: 3116 LKCKVKGEPRPKIKWTKEGKEVEMSARVRAEHKDDGTL-TLTFDNVTQADAGEYRCEAENEYGSAWTEGPIIVTLEGAPKIDGEAPDF-LQPVKPAVVTVGETAVLEGKI-SGKPKPSVKWYKNGEEL------KPSDRVKIENLDDGTQRLTVTNAKLDDMDEYRCEASNEF 3279

HSP 3 Score: 47.3654 bits (111), Expect = 9.954e-6
Identity = 30/109 (27.52%), Postives = 52/109 (47.71%), Query Frame = 1

Query:  505 CQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEYFHLKSSASW--VLVMNSFSDLIFDISIKQISQKTGDDVEMLCD 825
            C    G P P   W+KD  +L       + +R  F ++E G  +M I  ++++D+G Y C+A NEY    +SA +  + V    +   F   ++    K GD ++  C+
Sbjct:  568 CLKVTGYPLPDITWYKDDVQL------HEDERHTFYSDEDGFFAMTIDPVQVTDTGRYTCMATNEYGQASTSAFFRVLKVEKEAAPPAFVTKLRDKECKEGDVIDFECE 670

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Celegans
Match: unc-89 (Muscle M-line assembly protein unc-89 [Source:UniProtKB/Swiss-Prot;Acc:O01761])

HSP 1 Score: 58.5362 bits (140), Expect = 2.458e-9
Identity = 49/193 (25.39%), Postives = 90/193 (46.63%), Query Frame = 1

Query:  157 ITRLSDDYFPRSGSLKLICVAEGNPMPTITW-HDTKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYE--FYCNASNDKTWIVSK---SVKTGLSYLSPTYKIQPESIQILK-----EFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEY 702
            I  L D     S  + L C   G P P ++W HD KT +         +  +S +G+  ++    +++++  + C A N +    ++   +V+   S  + T +  PE +++L+     E Q  IL C++  G P PK KW K+ +E+      +   R    + + G  ++   ++  +D+GEY C A NEY
Sbjct: 2997 IVALQDKTTKTSEKVVLECKVIGEPKPKVSWLHDNKTIT------QESITVESVEGVERVTITSSELSHQGKYTCIAENTEGTSKTEAFLTVQDTASSKTDTGRGAPEFVELLRSCTVTEKQQAILKCKV-KGEPRPKIKWTKEGKEV------EMSARVRAEHKDDGTLTLTFDNVTQADAGEYRCEAENEY 3176

HSP 2 Score: 47.7506 bits (112), Expect = 7.133e-6
Identity = 43/173 (24.86%), Postives = 68/173 (39.31%), Query Frame = 1

Query:  205 LICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASND--KTW-----IVSKSVKTGLSYLSPTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEY 702
            L C  +G P P I W     +  M      + K D     L   N       E+ C A N+    W     IV+      +   +P + +QP    ++   ++ +L  ++  G P P  KW+K+  EL          R    N + G   + + + KL D  EY C A+NE+
Sbjct: 3116 LKCKVKGEPRPKIKWTKEGKEVEMSARVRAEHKDDGTL-TLTFDNVTQADAGEYRCEAENEYGSAWTEGPIIVTLEGAPKIDGEAPDF-LQPVKPAVVTVGETAVLEGKI-SGKPKPSVKWYKNGEEL------KPSDRVKIENLDDGTQRLTVTNAKLDDMDEYRCEASNEF 3279

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Fly
Match: robo3 (gene:FBgn0041097 transcript:FBtr0077921)

HSP 1 Score: 65.4698 bits (158), Expect = 1.171e-11
Identity = 50/197 (25.38%), Postives = 90/197 (45.69%), Query Frame = 1

Query:  112 FLKTWTNASFFHTIRITRLS-DDYFPRSGSLKLICVAEGNPMPTITWH-DTKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKTGLSYLSPTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANN 696
            FL  WT+A   H  RI     D   PR     L C AEG+P PTI W+ D     ++     + L       L ++++ +      ++C A N+     S++    ++ L   ++++P++ +I  +  + +L C  P G P P   W K  ++L    ++   +  I    + GN  + I+  + +D G+Y C+A N
Sbjct:   10 FLLKWTHAQGSHPPRIVEHPIDTTVPRHEPATLNCKAEGSPTPTIQWYKDGVPLKILPGSHRITLPAGGLFFLKVVNSRRETDAGIYWCEAKNELGVARSRNATLQVAVLRDEFRLEPQNTRI-AQGDTALLECAAPRGIPEPTVTWKKGGQKL---DLEGSKRVRIV---DGGN--LAIQDARQTDEGQYQCIAKN 197

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Fly
Match: robo3 (gene:FBgn0041097 transcript:FBtr0335384)

HSP 1 Score: 65.4698 bits (158), Expect = 1.171e-11
Identity = 50/197 (25.38%), Postives = 90/197 (45.69%), Query Frame = 1

Query:  112 FLKTWTNASFFHTIRITRLS-DDYFPRSGSLKLICVAEGNPMPTITWH-DTKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKTGLSYLSPTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANN 696
            FL  WT+A   H  RI     D   PR     L C AEG+P PTI W+ D     ++     + L       L ++++ +      ++C A N+     S++    ++ L   ++++P++ +I  +  + +L C  P G P P   W K  ++L    ++   +  I    + GN  + I+  + +D G+Y C+A N
Sbjct:   10 FLLKWTHAQGSHPPRIVEHPIDTTVPRHEPATLNCKAEGSPTPTIQWYKDGVPLKILPGSHRITLPAGGLFFLKVVNSRRETDAGIYWCEAKNELGVARSRNATLQVAVLRDEFRLEPQNTRI-AQGDTALLECAAPRGIPEPTVTWKKGGQKL---DLEGSKRVRIV---DGGN--LAIQDARQTDEGQYQCIAKN 197

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Fly
Match: robo2 (gene:FBgn0002543 transcript:FBtr0329985)

HSP 1 Score: 63.929 bits (154), Expect = 5.123e-11
Identity = 43/186 (23.12%), Postives = 81/186 (43.55%), Query Frame = 1

Query:  172 DDYFPRSGSLKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQ--------GLL---IISNPQPKITYEFYCNASNDKTWIVSKSVKTGLSYLSPTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANN 696
            D   P++      C AEGNP PTI W          + D  +LKTD+          GL    +I + +      ++C A N+     S++    +++L   ++++P + ++  + +  ++ C  P G+P P+  W K+ + L    + +   R +   N      + I+  + SD G Y C+  N
Sbjct:   99 DTTVPKNDPFTFNCQAEGNPTPTIQW----------FKDGRELKTDTGSHRIMLPAGGLFFLKVIHSRRESDAGTYWCEAKNEFGVARSRNATLQVAFLRDEFRLEPANTRV-AQGEVALMECGAPRGSPEPQISWRKNGQTL--NLVGNKRIRIVDGGN------LAIQEARQSDDGRYQCVVKN 265

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Fly
Match: robo2 (gene:FBgn0002543 transcript:FBtr0077941)

HSP 1 Score: 63.5438 bits (153), Expect = 6.121e-11
Identity = 43/186 (23.12%), Postives = 81/186 (43.55%), Query Frame = 1

Query:  172 DDYFPRSGSLKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQ--------GLL---IISNPQPKITYEFYCNASNDKTWIVSKSVKTGLSYLSPTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANN 696
            D   P++      C AEGNP PTI W          + D  +LKTD+          GL    +I + +      ++C A N+     S++    +++L   ++++P + ++  + +  ++ C  P G+P P+  W K+ + L    + +   R +   N      + I+  + SD G Y C+  N
Sbjct:   99 DTTVPKNDPFTFNCQAEGNPTPTIQW----------FKDGRELKTDTGSHRIMLPAGGLFFLKVIHSRRESDAGTYWCEAKNEFGVARSRNATLQVAFLRDEFRLEPANTRV-AQGEVALMECGAPRGSPEPQISWRKNGQTL--NLVGNKRIRIVDGGN------LAIQEARQSDDGRYQCVVKN 265

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Fly
Match: robo1 (gene:FBgn0005631 transcript:FBtr0071922)

HSP 1 Score: 60.8474 bits (146), Expect = 4.456e-10
Identity = 52/199 (26.13%), Postives = 91/199 (45.73%), Query Frame = 1

Query:  163 RLSDDYFPRSGSLKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKTGLSYLS------PTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEYFHLKSSASWVLVM 741
            R S+     +G ++L C+A GNP P++ W      +LM  + +   +  +  G L I++ + +    + C+A    + + S +V+  L   S      P  +I P + Q L +     L C+   GNP P+ KWF D      +++Q   +  I   +     S+++  L+LSDSG Y C A+ E    +   SW   +
Sbjct:  350 RPSNKKVGLNGVVQLPCMASGNPPPSVFWTKEGVSTLMFPNSSHGRQHVAADGTLQITDVRQEDEGYYVCSAF---SVVDSSTVRVFLQVSSLDERPPPIIQIGPAN-QTLPKGSVATLPCR-ATGNPSPRIKWFHD-----GHAVQAGNRYSIIQGS-----SLRVDDLQLSDSGTYTCTASGE----RGETSWAATL 529

HSP 2 Score: 54.299 bits (129), Expect = 5.668e-8
Identity = 46/178 (25.84%), Postives = 73/178 (41.01%), Query Frame = 1

Query:  205 LICVAEGNPMPTITWH--------DTKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKTGLSYLSPTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEH------GNCSMQIKHLKLSDSGEYHCLANN 696
            L C  EG P PTI W         + K    +Q+ D       + QG       + +   E++C A N     VS+     ++ L   ++++P+  ++ K  ++ +L C  P G P P   W KD   L      DD K   F  +        GN  + I +++  D G Y C+A N
Sbjct:   75 LNCKVEGKPEPTIEWFKDGEPVSTNEKKSHRVQFKDGALFFYRTMQG------KKEQDGGEYWCVAKNRVGQAVSRHASLQIAVLRDDFRVEPKDTRVAKG-ETALLECGPPKGIPEPTLIWIKDGVPL------DDLKAMSFGASSRVRIVDGGN--LLISNVEPIDEGNYKCIAQN 237

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Zebrafish
Match: cntn3b (contactin 3b [Source:ZFIN;Acc:ZDB-GENE-130530-645])

HSP 1 Score: 65.4698 bits (158), Expect = 1.898e-11
Identity = 64/267 (23.97%), Postives = 119/267 (44.57%), Query Frame = 1

Query:   43 INNKIVKKRMWYFVILVIFYQHGFLKTWTNASFFHTIRITRLSDDYFP--RSGSLKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKTGLSYLSPTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYS-IQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEYFHLKSSASWVLVMN--SFSDLIFDISIKQISQKTGDDVEMLCDP 828
            +NN I K+R++     ++    G +  +      H         D  P  +  +LKL C A GNP+P I+W  T   S + + + + LK  +   +L I + Q + T  + C A N +      + +  +S+ +  + +Q  +   +   +++   C+  +G P P   W K+   L+    +Q +            N ++ I  L LSD G Y C+A N++  + SSA  +++ +  SFS      ++K    ++G DV + C P
Sbjct:  204 VNNTITKERVFSSPTPLVLRNDGAMGEYEPKIELHF-------PDTIPAAKGSALKLECFALGNPVPRISWRRT---SDVSFPNKVKLK--NSNAILEIPSFQQEDTGTYECIAENSRG---KNAARGRVSFHATPHWLQTMTDTAMSIEENLFWECK-ANGKPKPSYSWLKNGESLISEGRVQIE------------NGALSIFSLNLSDGGMYQCVAENKHGIIYSSAELMVLASAPSFSQNPLSQTLK---ARSGSDVSLDCRP 439

HSP 2 Score: 51.6026 bits (122), Expect = 5.500e-7
Identity = 47/173 (27.17%), Postives = 77/173 (44.51%), Query Frame = 1

Query:  178 YFPRSGSLKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKTGLSYLSPTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANN 696
            Y P+  ++ L C A G P P   W    T   +  D+   L   S   L+I    + + +  + C A N +  I+S+      +YL   +K Q  S   ++E Q V+L C  P  +      W  ++     + +Q D +RF+  + E GN  + I  ++ SD G Y C+ NN
Sbjct:   46 YSPQQEAV-LSCEASGAPSPQYRWSLNGTLIDLGGDERRRL---SGGNLIITGLDRDQDSGVYQCTAFNTRGTILSQRATLQFAYLE-NFKTQTRSAVNVREGQGVVLLCGTPLHSGELTFTWVFNE---YPHFVQQDSRRFV--SQETGN--LYIAKVEPSDVGNYTCVVNN 206

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Zebrafish
Match: cntn4 (contactin 4 [Source:ZFIN;Acc:ZDB-GENE-060929-776])

HSP 1 Score: 64.3142 bits (155), Expect = 4.094e-11
Identity = 59/219 (26.94%), Postives = 100/219 (45.66%), Query Frame = 1

Query:  187 RSGSLKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKTGLSYL-SPTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEYFHLKSSASWVLVMNSFSDLIFDISIKQISQKT----GDDVEMLCDP 828
            +  +++L C A GNP+P+I+W        + +   +D++  S  G++ I   Q +    + C A N K      SV+  LS+  SP    +P+ +Q   +  S++  C+   G P P  +W K+   L       +P   +    +  N ++ I HL LSD G Y C+A N+Y  + S+A   ++      +  D S  Q+   T    G DV + C P
Sbjct:  113 KGSTVRLECFALGNPVPSISWRRVDG---VPFARKVDVRKTS--GVMEIPYFQQEDAGTYECVAENSKG---RNSVQGKLSFFASPQLIEKPQDVQKPID-DSLVWECK-ATGKPKPSYRWMKNGENL-------EPTERV----QVINGALSITHLALSDIGMYQCVAGNKYGEVYSNAELRVIA-----VAPDFSQNQLKSHTLVKEGGDVLIECKP 305

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Zebrafish
Match: cntn4 (contactin 4 [Source:ZFIN;Acc:ZDB-GENE-060929-776])

HSP 1 Score: 63.1586 bits (152), Expect = 9.618e-11
Identity = 59/219 (26.94%), Postives = 99/219 (45.21%), Query Frame = 1

Query:  187 RSGSLKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKTGLSYL-SPTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEYFHLKSSASWVLVMNSFSDLIFDISIKQISQKT----GDDVEMLCDP 828
            +  +++L C A GNP+P+I+W        + +   +D++  S  G++ I   Q +    + C A N K      SV+  LS+  SP    +P+ +Q   +  S++  C+   G P P  +W K+   L     +   +R    N      ++ I HL LSD G Y C+A N+Y  + S+A   ++      +  D S  Q+   T    G DV + C P
Sbjct:  242 KGSTVRLECFALGNPVPSISWRRVDG---VPFARKVDVRKTS--GVMEIPYFQQEDAGTYECVAENSKG---RNSVQGKLSFFASPQLIEKPQDVQKPID-DSLVWECK-ATGKPKPSYRWMKNGENL-----EPTEERVQVING-----ALSITHLALSDIGMYQCVAGNKYGEVYSNAELRVIA-----VAPDFSQNQLKSHTLVKEGGDVLIECKP 435

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Zebrafish
Match: cntn4 (contactin 4 [Source:ZFIN;Acc:ZDB-GENE-060929-776])

HSP 1 Score: 63.1586 bits (152), Expect = 9.995e-11
Identity = 59/219 (26.94%), Postives = 99/219 (45.21%), Query Frame = 1

Query:  187 RSGSLKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKTGLSYL-SPTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEYFHLKSSASWVLVMNSFSDLIFDISIKQISQKT----GDDVEMLCDP 828
            +  +++L C A GNP+P+I+W        + +   +D++  S  G++ I   Q +    + C A N K      SV+  LS+  SP    +P+ +Q   +  S++  C+   G P P  +W K+   L     +   +R    N      ++ I HL LSD G Y C+A N+Y  + S+A   ++      +  D S  Q+   T    G DV + C P
Sbjct:  126 KGSTVRLECFALGNPVPSISWRRVDG---VPFARKVDVRKTS--GVMEIPYFQQEDAGTYECVAENSKG---RNSVQGKLSFFASPQLIEKPQDVQKPID-DSLVWECK-ATGKPKPSYRWMKNGENL-----EPTEERVQVING-----ALSITHLALSDIGMYQCVAGNKYGEVYSNAELRVIA-----VAPDFSQNQLKSHTLVKEGGDVLIECKP 319

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Zebrafish
Match: cntn4 (contactin 4 [Source:ZFIN;Acc:ZDB-GENE-060929-776])

HSP 1 Score: 63.1586 bits (152), Expect = 1.008e-10
Identity = 59/219 (26.94%), Postives = 99/219 (45.21%), Query Frame = 1

Query:  187 RSGSLKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKTGLSYL-SPTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEYFHLKSSASWVLVMNSFSDLIFDISIKQISQKT----GDDVEMLCDP 828
            +  +++L C A GNP+P+I+W        + +   +D++  S  G++ I   Q +    + C A N K      SV+  LS+  SP    +P+ +Q   +  S++  C+   G P P  +W K+   L     +   +R    N      ++ I HL LSD G Y C+A N+Y  + S+A   ++      +  D S  Q+   T    G DV + C P
Sbjct:   96 KGSTVRLECFALGNPVPSISWRRVDG---VPFARKVDVRKTS--GVMEIPYFQQEDAGTYECVAENSKG---RNSVQGKLSFFASPQLIEKPQDVQKPID-DSLVWECK-ATGKPKPSYRWMKNGENL-----EPTEERVQVING-----ALSITHLALSDIGMYQCVAGNKYGEVYSNAELRVIA-----VAPDFSQNQLKSHTLVKEGGDVLIECKP 289

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Xenopus
Match: cep131 (centrosomal protein 131kDa [Source:Xenbase;Acc:XB-GENE-1016768])

HSP 1 Score: 68.5514 bits (166), Expect = 1.998e-12
Identity = 58/223 (26.01%), Postives = 98/223 (43.95%), Query Frame = 1

Query:  178 YFPRS------GSLKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKTGLSYLSPTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEYFHLKSSASWVLVMNSFSDLIFDISIKQISQKTGDDVEMLCDP 828
            +FP S       ++KL C A GNP+PTITW     K +     +  ++     G+L I N Q +    + C A N +       V+  L+Y +P   +Q  +   +   ++++  C+   G P     W K+ + L              S  +HG  S+ I  + +SDSG Y CLA N++  + SSA   ++  S +  +  +++     K G  V + C P
Sbjct:  225 HFPESVPSAKGSTVKLECFALGNPVPTITWRRADGKPI-----SRKVRRHRSSGVLEIPNFQQEDAGPYECVAENTRG---KNMVRGQLTYFAPPTWVQKINDAHIAIEENILWECK-ASGRPKASYTWLKNGQRLQ-------------SKIDHG--SLTITSVNISDSGMYQCLAENKHGTIYSSAELRVIGKSINPNVSRVTLG----KVGGSVLIECKP 419

HSP 2 Score: 58.5362 bits (140), Expect = 5.088e-9
Identity = 46/168 (27.38%), Postives = 81/168 (48.21%), Query Frame = 1

Query:  196 SLKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNP-QPKITYEFYCNASNDKTWIVSKSVKTGLSYLSPTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANN 696
            +L+L+C  +G+P P + W    T  LM  D+A D +       LII++P + +    F C A+N    I+S+      SYL  +++ +  S   ++E Q ++L C  P  +      W  ++       +Q D +RF+  +   GN  + I  ++ SD+G Y C+  N
Sbjct:   38 TLRLVCEVQGHPKPVVRWRVNGT--LM--DEAQDYRYRVLDRSLIIASPDRNRDVGTFQCEATNSLGTILSREAYVQFSYLD-SFQTRTRSTVSVREGQGMVLLCGPPAHSGELVYAWIFNEYPPF---VQQDNRRFV--SQVTGN--LYIAKVEPSDAGNYTCVVTN 193

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Xenopus
Match: polr1e (polymerase (RNA) I polypeptide E [Source:Xenbase;Acc:XB-GENE-1003651])

HSP 1 Score: 66.6254 bits (161), Expect = 9.200e-12
Identity = 55/183 (30.05%), Postives = 83/183 (45.36%), Query Frame = 1

Query:  196 SLKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKT---GLSYL----SPTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEYFHLKSSA 723
            ++   C AEGNP P I W     +  M+ D  ++L  D   G L+I N +      + C A N     V+  VKT    L Y     +PT+ IQP++ ++L   +SV L C    G P P+  W +  R  L      DP+  I  +       + I+++   D+GEY C A N    + S+A
Sbjct:   88 TVYFTCRAEGNPKPEIIWLRNNNELSMKDDSRLNLLND---GTLMIQNTKETDQGIYQCMAKN-----VAGEVKTHEVTLRYYGTPATPTFVIQPQNTEVLVG-ESVTLECS-ATGQPHPRVTWTRGDRTPLP----SDPRINITPSG-----GLYIQNVNQDDAGEYTCFATNSVETIHSTA 251

HSP 2 Score: 49.2914 bits (116), Expect = 5.248e-6
Identity = 51/209 (24.40%), Postives = 90/209 (43.06%), Query Frame = 1

Query:  196 SLKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKTGLSYLSPTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEYFHLKSSASWVLVMNSFSDLIFDISIKQISQKTGDDVEMLC 822
            S+ L C A G P P +TW     ++ +  D  +++   +  G L I N       E+ C A+N    I S +    +    P + + P+   +  E  +V   C+   GNP P   W K   +L       D +  + S+      +++I  + L D G+Y C A N     KS+A+ ++V    +  +F      ++ + G DV++ C
Sbjct:  184 SVTLECSATGQPHPRVTW-TRGDRTPLPSDPRINI---TPSGGLYIQNVNQDDAGEYTCFATNSVETIHSTAYI--IVQAVPQFTVVPQDRNVF-EGHTVDFHCE-AQGNPKPVIAWTKGGNQL-----SVDRRHQVLSSG-----TLRILRVALHDQGQYECQAVN-IVGSKSTAAQLIVQTRVTP-VFATVPNDMTVEVGTDVQIPC 372

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Xenopus
Match: polr1e (polymerase (RNA) I polypeptide E [Source:Xenbase;Acc:XB-GENE-1003651])

HSP 1 Score: 66.6254 bits (161), Expect = 9.635e-12
Identity = 55/183 (30.05%), Postives = 83/183 (45.36%), Query Frame = 1

Query:  196 SLKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKT---GLSYL----SPTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEYFHLKSSA 723
            ++   C AEGNP P I W     +  M+ D  ++L  D   G L+I N +      + C A N     V+  VKT    L Y     +PT+ IQP++ ++L   +SV L C    G P P+  W +  R  L      DP+  I  +       + I+++   D+GEY C A N    + S+A
Sbjct:  255 TVYFTCRAEGNPKPEIIWLRNNNELSMKDDSRLNLLND---GTLMIQNTKETDQGIYQCMAKN-----VAGEVKTHEVTLRYYGTPATPTFVIQPQNTEVLVG-ESVTLECS-ATGQPHPRVTWTRGDRTPLP----SDPRINITPSG-----GLYIQNVNQDDAGEYTCFATNSVETIHSTA 418

HSP 2 Score: 49.2914 bits (116), Expect = 5.328e-6
Identity = 51/209 (24.40%), Postives = 90/209 (43.06%), Query Frame = 1

Query:  196 SLKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKTGLSYLSPTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEYFHLKSSASWVLVMNSFSDLIFDISIKQISQKTGDDVEMLC 822
            S+ L C A G P P +TW     ++ +  D  +++   +  G L I N       E+ C A+N    I S +    +    P + + P+   +  E  +V   C+   GNP P   W K   +L       D +  + S+      +++I  + L D G+Y C A N     KS+A+ ++V    +  +F      ++ + G DV++ C
Sbjct:  351 SVTLECSATGQPHPRVTW-TRGDRTPLPSDPRINI---TPSGGLYIQNVNQDDAGEYTCFATNSVETIHSTAYI--IVQAVPQFTVVPQDRNVF-EGHTVDFHCE-AQGNPKPVIAWTKGGNQL-----SVDRRHQVLSSG-----TLRILRVALHDQGQYECQAVN-IVGSKSTAAQLIVQTRVTP-VFATVPNDMTVEVGTDVQIPC 539

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Xenopus
Match: polr1e (polymerase (RNA) I polypeptide E [Source:Xenbase;Acc:XB-GENE-1003651])

HSP 1 Score: 66.6254 bits (161), Expect = 9.701e-12
Identity = 55/183 (30.05%), Postives = 83/183 (45.36%), Query Frame = 1

Query:  196 SLKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKT---GLSYL----SPTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEYFHLKSSA 723
            ++   C AEGNP P I W     +  M+ D  ++L  D   G L+I N +      + C A N     V+  VKT    L Y     +PT+ IQP++ ++L   +SV L C    G P P+  W +  R  L      DP+  I  +       + I+++   D+GEY C A N    + S+A
Sbjct:  231 TVYFTCRAEGNPKPEIIWLRNNNELSMKDDSRLNLLND---GTLMIQNTKETDQGIYQCMAKN-----VAGEVKTHEVTLRYYGTPATPTFVIQPQNTEVLVG-ESVTLECS-ATGQPHPRVTWTRGDRTPLP----SDPRINITPSG-----GLYIQNVNQDDAGEYTCFATNSVETIHSTA 394

HSP 2 Score: 49.2914 bits (116), Expect = 5.318e-6
Identity = 51/209 (24.40%), Postives = 90/209 (43.06%), Query Frame = 1

Query:  196 SLKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKTGLSYLSPTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEYFHLKSSASWVLVMNSFSDLIFDISIKQISQKTGDDVEMLC 822
            S+ L C A G P P +TW     ++ +  D  +++   +  G L I N       E+ C A+N    I S +    +    P + + P+   +  E  +V   C+   GNP P   W K   +L       D +  + S+      +++I  + L D G+Y C A N     KS+A+ ++V    +  +F      ++ + G DV++ C
Sbjct:  327 SVTLECSATGQPHPRVTW-TRGDRTPLPSDPRINI---TPSGGLYIQNVNQDDAGEYTCFATNSVETIHSTAYI--IVQAVPQFTVVPQDRNVF-EGHTVDFHCE-AQGNPKPVIAWTKGGNQL-----SVDRRHQVLSSG-----TLRILRVALHDQGQYECQAVN-IVGSKSTAAQLIVQTRVTP-VFATVPNDMTVEVGTDVQIPC 515

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Xenopus
Match: polr1e (polymerase (RNA) I polypeptide E [Source:Xenbase;Acc:XB-GENE-1003651])

HSP 1 Score: 66.6254 bits (161), Expect = 9.712e-12
Identity = 55/183 (30.05%), Postives = 83/183 (45.36%), Query Frame = 1

Query:  196 SLKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKT---GLSYL----SPTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEYFHLKSSA 723
            ++   C AEGNP P I W     +  M+ D  ++L  D   G L+I N +      + C A N     V+  VKT    L Y     +PT+ IQP++ ++L   +SV L C    G P P+  W +  R  L      DP+  I  +       + I+++   D+GEY C A N    + S+A
Sbjct:  321 TVYFTCRAEGNPKPEIIWLRNNNELSMKDDSRLNLLND---GTLMIQNTKETDQGIYQCMAKN-----VAGEVKTHEVTLRYYGTPATPTFVIQPQNTEVLVG-ESVTLECS-ATGQPHPRVTWTRGDRTPLP----SDPRINITPSG-----GLYIQNVNQDDAGEYTCFATNSVETIHSTA 484

HSP 2 Score: 49.2914 bits (116), Expect = 5.411e-6
Identity = 51/209 (24.40%), Postives = 90/209 (43.06%), Query Frame = 1

Query:  196 SLKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKTGLSYLSPTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEYFHLKSSASWVLVMNSFSDLIFDISIKQISQKTGDDVEMLC 822
            S+ L C A G P P +TW     ++ +  D  +++   +  G L I N       E+ C A+N    I S +    +    P + + P+   +  E  +V   C+   GNP P   W K   +L       D +  + S+      +++I  + L D G+Y C A N     KS+A+ ++V    +  +F      ++ + G DV++ C
Sbjct:  417 SVTLECSATGQPHPRVTW-TRGDRTPLPSDPRINI---TPSGGLYIQNVNQDDAGEYTCFATNSVETIHSTAYI--IVQAVPQFTVVPQDRNVF-EGHTVDFHCE-AQGNPKPVIAWTKGGNQL-----SVDRRHQVLSSG-----TLRILRVALHDQGQYECQAVN-IVGSKSTAAQLIVQTRVTP-VFATVPNDMTVEVGTDVQIPC 605

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Mouse
Match: Pxdn (peroxidasin [Source:MGI Symbol;Acc:MGI:1916925])

HSP 1 Score: 73.559 bits (179), Expect = 4.506e-14
Identity = 61/195 (31.28%), Postives = 91/195 (46.67%), Query Frame = 1

Query:  154 RITRLSDDYFPRSG-SLKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKTGLSYLS----PTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEYFHLKSSA 723
            RIT    D    SG ++   C AEGNP P I W     +  M+ D  ++L  D   G L+I N Q      + C A N      +K+ +  L YL     PT+ IQP++ ++L   +SV L C    G+P P+  W +  R  L      DP+  I  +       + I+++  SDSGEY C A+N    + ++A
Sbjct:   64 RITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDD---GTLMIQNTQEADEGVYQCMAKNVAG--EAKTQEVTLRYLGSPARPTFVIQPQNTEVLVG-ESVTLECS-ATGHPLPQITWTRGDRTPLPI----DPRVNITPSG-----GLYIQNVAQSDSGEYTCFASNSVDSIHATA 242

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Mouse
Match: Robo4 (roundabout guidance receptor 4 [Source:MGI Symbol;Acc:MGI:1921394])

HSP 1 Score: 72.0182 bits (175), Expect = 5.084e-14
Identity = 62/238 (26.05%), Postives = 97/238 (40.76%), Query Frame = 1

Query:   73 WYFVILVIFYQHGFLKTWTNASFFHTIRITRLSDDYFPRSGSLKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNP----QPK--------ITYEFYCNASNDKTWIVSKSVKTGLSYLSPTYKIQP-ESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEYFHLKSSASWVLVMNS 747
            W   +L++F   G           H        D     SG  K+ C + G P PTI W        M   D   L  D   G L++  P    +P+        I   + C ASN     VS+  +  ++ L   ++IQP +++ ++ E  S++L C  P G P P   W+KD + L+       P R   S +     S+ +   + +DSG Y C+A N     +S A+ V +  S
Sbjct:   23 WPLPLLLLFIMGGEALDSPPQILVHP------QDQLLQGSGPAKMRCRSSGQPPPTIRWLLNGQPLSMATPDLHYLLPD---GTLLLHRPSVQGRPQDDQNILSAILGVYTCEASNRLGTAVSRGARLSVAVLQEDFQIQPRDTVAVVGE--SLVLECGPPWGYPKPSVSWWKDGKPLVL-----QPGRRTVSGD-----SLMVSRAEKNDSGTYMCMATNNAGQRESRAARVSIQES 239

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Mouse
Match: Pxdn (peroxidasin [Source:MGI Symbol;Acc:MGI:1916925])

HSP 1 Score: 73.1738 bits (178), Expect = 5.237e-14
Identity = 61/195 (31.28%), Postives = 91/195 (46.67%), Query Frame = 1

Query:  154 RITRLSDDYFPRSG-SLKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKTGLSYLS----PTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEYFHLKSSA 723
            RIT    D    SG ++   C AEGNP P I W     +  M+ D  ++L  D   G L+I N Q      + C A N      +K+ +  L YL     PT+ IQP++ ++L   +SV L C    G+P P+  W +  R  L      DP+  I  +       + I+++  SDSGEY C A+N    + ++A
Sbjct:  244 RITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDD---GTLMIQNTQEADEGVYQCMAKNVAG--EAKTQEVTLRYLGSPARPTFVIQPQNTEVLVG-ESVTLECS-ATGHPLPQITWTRGDRTPLPI----DPRVNITPSG-----GLYIQNVAQSDSGEYTCFASNSVDSIHATA 422

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Mouse
Match: Cntn4 (contactin 4 [Source:MGI Symbol;Acc:MGI:1095737])

HSP 1 Score: 68.5514 bits (166), Expect = 1.503e-12
Identity = 63/223 (28.25%), Postives = 101/223 (45.29%), Query Frame = 1

Query:  187 RSGSLKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKTGLSYLSPTYKIQPESIQILKEF-----QSVILSCQLPDGNPPPKTKWFKDQRELL-KYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEYFHLKSSASWVLVMNS--FSDLIFDISIKQIS-QKTGDDVEMLCDP 828
            +  ++KL C A GNP+PTI W     K +     A   +     G+L I N Q +    + C A N +   V+K           T+  QP  +QI+ +      +SV   C+  +G P P  +W K+   LL +  IQ           E G  ++ I  + LSD+G Y C+A N++  + SSA   ++  S  FS  +    +K+++  K G +V + C P
Sbjct:  239 KGTTVKLECFALGNPVPTILWRRADGKPI-----ARKARRHKSNGILEIPNFQQEDAGSYECVAENSRGKNVAKG--------QLTFYAQPNWVQIINDIHVAMEESVFWECKA-NGRPKPTYRWLKNGDPLLTRDRIQI----------EQG--TLNITIVNLSDAGMYQCVAENKHGVIFSSAELSVIAESPDFSRTL----LKRVTLVKVGGEVVIECKP 431

HSP 2 Score: 63.1586 bits (152), Expect = 8.366e-11
Identity = 52/169 (30.77%), Postives = 76/169 (44.97%), Query Frame = 1

Query:  199 LKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNP---QPKITYEFYCNASNDKTWIVSKSVKTGLSYLSPTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANN 696
            +KL C  +GNP P I W    T      D  MD +     G L+I+NP   Q   TY+  C A+N    IVS+  K   +YL   +K +  S   ++  Q ++L C      PPP +          +Y    D +RF+  + E GN  + I  ++ SD G Y C+  N
Sbjct:   46 VKLSCEVKGNPKPHIRWKINGT----DVDIGMDFRYSVVDGSLLINNPNKTQDAGTYQ--CIATNSFGTIVSREAKLQFAYLE-NFKTRTRSTVSVRRGQGMVLLC-----GPPPHSGELSYAWIFNEYPSYQDNRRFV--SQETGN--LYIAKVEKSDVGNYTCVVTN 198

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Mouse
Match: Robo4 (roundabout guidance receptor 4 [Source:MGI Symbol;Acc:MGI:1921394])

HSP 1 Score: 68.1662 bits (165), Expect = 2.224e-12
Identity = 57/205 (27.80%), Postives = 89/205 (43.41%), Query Frame = 1

Query:  172 DDYFPRSGSLKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNP----QPK--------ITYEFYCNASNDKTWIVSKSVKTGLSYLSPTYKIQP-ESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEYFHLKSSASWVLVMNS 747
            D     SG  K+ C + G P PTI W        M   D   L  D   G L++  P    +P+        I   + C ASN     VS+  +  ++ L   ++IQP +++ ++ E  S++L C  P G P P   W+KD + L+       P R   S +     S+ +   + +DSG Y C+A N     +S A+ V +  S
Sbjct:   50 DQLLQGSGPAKMRCRSSGQPPPTIRWLLNGQPLSMATPDLHYLLPD---GTLLLHRPSVQGRPQDDQNILSAILGVYTCEASNRLGTAVSRGARLSVAVLQEDFQIQPRDTVAVVGE--SLVLECGPPWGYPKPSVSWWKDGKPLVL-----QPGRRTVSGD-----SLMVSRAEKNDSGTYMCMATNNAGQRESRAARVSIQES 239

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. UniProt/SwissProt
Match: sp|Q92626|PXDN_HUMAN (Peroxidasin homolog OS=Homo sapiens OX=9606 GN=PXDN PE=1 SV=2)

HSP 1 Score: 73.559 bits (179), Expect = 2.724e-13
Identity = 63/198 (31.82%), Postives = 90/198 (45.45%), Query Frame = 1

Query:  154 RITRLSDDYFPRSG-SLKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKT---GLSYLS----PTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEYFHLKSSA 723
            RIT    D    SG ++   C AEGNP P I W     +  M+ D  ++L  D   G L+I N Q      + C A N     V+  VKT    L Y      PT+ IQP++ ++L   +SV L C    G+PPP+  W +  R  L      DP+  I  +       + I+++   DSGEY C A N    + ++A
Sbjct:  247 RITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDD---GTLMIQNTQETDQGIYQCMAKN-----VAGEVKTQEVTLRYFGSPARPTFVIQPQNTEVLVG-ESVTLECS-ATGHPPPRISWTRGDRTPLPV----DPRVNITPSG-----GLYIQNVVQGDSGEYACSATNNIDSVHATA 425

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. UniProt/SwissProt
Match: sp|Q3UQ28|PXDN_MOUSE (Peroxidasin homolog OS=Mus musculus OX=10090 GN=Pxdn PE=1 SV=2)

HSP 1 Score: 73.1738 bits (178), Expect = 3.663e-13
Identity = 61/195 (31.28%), Postives = 91/195 (46.67%), Query Frame = 1

Query:  154 RITRLSDDYFPRSG-SLKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKTGLSYLS----PTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEYFHLKSSA 723
            RIT    D    SG ++   C AEGNP P I W     +  M+ D  ++L  D   G L+I N Q      + C A N      +K+ +  L YL     PT+ IQP++ ++L   +SV L C    G+P P+  W +  R  L      DP+  I  +       + I+++  SDSGEY C A+N    + ++A
Sbjct:  244 RITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDD---GTLMIQNTQEADEGVYQCMAKNVAG--EAKTQEVTLRYLGSPARPTFVIQPQNTEVLVG-ESVTLECS-ATGHPLPQITWTRGDRTPLPI----DPRVNITPSG-----GLYIQNVAQSDSGEYTCFASNSVDSIHATA 422

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. UniProt/SwissProt
Match: sp|Q80W87|ROBO4_RAT (Roundabout homolog 4 OS=Rattus norvegicus OX=10116 GN=Robo4 PE=2 SV=1)

HSP 1 Score: 72.4034 bits (176), Expect = 6.221e-13
Identity = 56/205 (27.32%), Postives = 92/205 (44.88%), Query Frame = 1

Query:  172 DDYFPRSGSLKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNP----QPK--------ITYEFYCNASNDKTWIVSKSVKTGLSYLSPTYKIQP-ESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEYFHLKSSASWVLVMNS 747
            D     SG  K+ C A G P+PTI W        M   D   L++D   G L++  P    +P+        I   + C ASN     VS+  +  ++ L   ++IQP +++ ++ E  S++L C  P G P P   W+KD + L+       P +   S +     S+ +   + +D+G Y C+A N     +S A+ V +  S
Sbjct:   50 DQLLQGSGPAKMSCRASGQPLPTIRWLLNGQPLSMATPDLHYLQSD---GTLLLHRPPTHGRPQDDQNILSAILGVYTCEASNRLGTAVSRGARLSVAVLQEDFRIQPRDTVAVVGE--SLVLECGPPWGYPKPSVSWWKDGKPLVL-----QPGKRTVSGD-----SLMVARAEKNDTGTYMCMATNNAGQRESRAARVSIQES 239

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. UniProt/SwissProt
Match: sp|Q8C310|ROBO4_MOUSE (Roundabout homolog 4 OS=Mus musculus OX=10090 GN=Robo4 PE=1 SV=2)

HSP 1 Score: 68.1662 bits (165), Expect = 1.674e-11
Identity = 57/205 (27.80%), Postives = 89/205 (43.41%), Query Frame = 1

Query:  172 DDYFPRSGSLKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNP----QPK--------ITYEFYCNASNDKTWIVSKSVKTGLSYLSPTYKIQP-ESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEYFHLKSSASWVLVMNS 747
            D     SG  K+ C + G P PTI W        M   D   L  D   G L++  P    +P+        I   + C ASN     VS+  +  ++ L   ++IQP +++ ++ E  S++L C  P G P P   W+KD + L+       P R   S +     S+ +   + +DSG Y C+A N     +S A+ V +  S
Sbjct:   40 DQLLQGSGPAKMRCRSSGQPPPTIRWLLNGQPLSMATPDLHYLLPD---GTLLLHRPSVQGRPQDDQNILSAILGVYTCEASNRLGTAVSRGARLSVAVLQEDFQIQPRDTVAVVGE--SLVLECGPPWGYPKPSVSWWKDGKPLVL-----QPGRRTVSGD-----SLMVSRAEKNDSGTYMCMATNNAGQRESRAARVSIQES 229

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. UniProt/SwissProt
Match: sp|Q62682|CNTN3_RAT (Contactin-3 OS=Rattus norvegicus OX=10116 GN=Cntn3 PE=1 SV=1)

HSP 1 Score: 67.3958 bits (163), Expect = 3.290e-11
Identity = 62/220 (28.18%), Postives = 101/220 (45.91%), Query Frame = 1

Query:  187 RSGSLKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKTGLSYLSPTYKIQPESIQILKEFQSVI-----LSCQLPDGNPPPKTKWFKDQREL-LKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEYFHLKSSASWVLVMNSFSDLIFDISIKQISQKTGDDVEMLCDP 828
            +  ++KL C A GNP+P I W  +     M +   + L+     G+L I N Q + T  + C A N +     K+V  G      TY  +P  +Q+LK+ ++ +       C+   G P P  +W K+   L L+  IQ +            N ++ I +L +SDSG + C+A N++  + SSA  + V+ S  D   +   K I  + G  V + C P
Sbjct:  241 KGSTVKLECFALGNPVPQINWRRSDG---MPFPTKIKLR--KFNGVLEIPNFQQEDTGSYECIAENSR----GKNVARG----RLTYYAKPYWVQLLKDVETAVEDSLYWECR-ASGKPKPSYRWLKNGDALVLEERIQIE------------NGALTIANLNVSDSGMFQCIAENKHGLIYSSAE-LKVLASAPDFSRNPMKKMIQVQVGSLVILDCKP 433

HSP 2 Score: 55.8398 bits (133), Expect = 2.151e-7
Identity = 49/182 (26.92%), Postives = 77/182 (42.31%), Query Frame = 1

Query:  169 SDDYFP---RSGSLKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKI-TYEFYCNASNDKTWIVSKSVKTGLSYLSPTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYS--IQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANN 696
            S+  FP       + L C A GNP P   W    +      D ++D +     G LI+ NP     T  + C A+N    IVS+  K   +YL   +K +  S   ++E Q V+L C      PPP +          +Y   +++D +RF+     H    + I  ++ SD G Y C+  +
Sbjct:   33 SNSIFPVGSEDKKITLNCEARGNPSPHYRWQLNGS----DIDTSLDHRYKLNGGNLIVINPNRNWDTGSYQCFATNSLGTIVSREAKLQFAYLE-NFKSRMRSRVSVREGQGVVLLC-----GPPPHSGELSYAWVFNEYPSFVEEDSRRFVSQETGH----LYIAKVEPSDVGNYTCVVTS 200

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. TrEMBL
Match: A0A0R3U7X5 (Uncharacterized protein OS=Mesocestoides corti OX=53468 GN=MCOS_LOCUS2946 PE=4 SV=1)

HSP 1 Score: 100.908 bits (250), Expect = 4.815e-20
Identity = 68/220 (30.91%), Postives = 101/220 (45.91%), Query Frame = 1

Query:  172 DDYFPRSGSLKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKTGLSYLS---PTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEYFHLKSSASWVLVMNSFSDLIFDISIKQISQKTGDDVEMLC 822
            +D FP +G+L+  C   G P P ITW+D  T+  ++   A ++        L I  P+PK  Y  YCN SN   W  S  V+ GL+YL    P + I   ++    E   V+L C  P GNPPP T+W  +  EL +   Q  P+             + I+ +KL +SG Y C A N    +++S S V+ +   +   F    K +    G  V+  C
Sbjct:   36 EDTFPVNGNLEFSCKGTGFPDPQITWYDANTRRPLKESTA-NVHMKQYLDRLTILQPEPKQVYAVYCNISNAAGWTASDVVRGGLAYLEYDFPRFPIDTSAV----EGDLVLLECHPPLGNPPPTTEWLFNGVELPRELGQVSPEG-----------DLHIQKVKLRNSGTYACRARNPS-GVRTSPSAVVTVKRKAPR-FIQKPKDVHASVGSTVQFFC 237

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. TrEMBL
Match: A0A5K3FNC5 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1)

HSP 1 Score: 100.523 bits (249), Expect = 5.433e-20
Identity = 68/220 (30.91%), Postives = 101/220 (45.91%), Query Frame = 1

Query:  172 DDYFPRSGSLKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKTGLSYLS---PTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEYFHLKSSASWVLVMNSFSDLIFDISIKQISQKTGDDVEMLC 822
            +D FP +G+L+  C   G P P ITW+D  T+  ++   A ++        L I  P+PK  Y  YCN SN   W  S  V+ GL+YL    P + I   ++    E   V+L C  P GNPPP T+W  +  EL +   Q  P+             + I+ +KL +SG Y C A N    +++S S V+ +   +   F    K +    G  V+  C
Sbjct:   77 EDTFPVNGNLEFSCKGTGFPDPQITWYDANTRRPLKESTA-NVHMKQYLDRLTILQPEPKQVYAVYCNISNAAGWTASDVVRGGLAYLEYDFPRFPIDTSAV----EGDLVLLECHPPLGNPPPTTEWLFNGVELPRELGQVSPEG-----------DLHIQKVKLRNSGTYACRARNPS-GVRTSPSAVVTVKRKAPR-FIQKPKDVHASVGSTVQFFC 278

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. TrEMBL
Match: A0A068Y9I9 (Roundabout 2 OS=Echinococcus multilocularis OX=6211 GN=EmuJ_000748500 PE=4 SV=1)

HSP 1 Score: 99.3673 bits (246), Expect = 1.542e-19
Identity = 58/175 (33.14%), Postives = 85/175 (48.57%), Query Frame = 1

Query:  172 DDYFPRSGSLKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKTGLSYLSPTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANN 696
            +D FP  G+L+  C   G P P I+WHD  T+  +  + A ++  +   G L I++P+ K TY  YCN SN   W+ S  V  GL+YL   +   P   + ++E   V+L CQ P GNP P T+W  +  EL        P      + E     + I+ +K   +G Y C A N
Sbjct:   37 EDIFPLEGNLEFSCKGTGFPEPQISWHDANTRKRLD-ESASNIHVNQYLGRLTIADPEVKRTYSVYCNISNTAGWVASSVVHGGLAYLEHDFPRFPID-KTVEEGDLVLLECQPPMGNPTPTTEWLYNNAEL--------PPGLGLISPEG---DLHIREVKPKHAGTYACRARN 198

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. TrEMBL
Match: A0A504YEM6 (Uncharacterized protein OS=Fasciola gigantica OX=46835 GN=FGIG_06134 PE=4 SV=1)

HSP 1 Score: 99.3673 bits (246), Expect = 1.730e-19
Identity = 59/196 (30.10%), Postives = 100/196 (51.02%), Query Frame = 1

Query:  154 RITRLSDDYFPRSGSLKLICVAEGNPMPTITWHDTKTKSLM-----QYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVS-KSVKTGLSYLSPTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELL-KYSIQDDPKRFIFSNNEHGNCS--------MQIKHLKLSDSGEYHCLANN 696
            RI     D +   G L+  C AEGNP P I W+++  K L+       +    +  +   G L+ISNP     Y FYCNASN+  W +S + V+ G +YL  ++++ P++ Q + E  +V + C+ P G P P   W ++ + +  + ++ D+P +F   +N   + +        +QI H++  D+G Y C A N
Sbjct:   40 RIVEAPTDQYSADGFLEFTCRAEGNPQPIIQWYNSTDKKLVTDRIPSAESLSGIHVNKHYGRLMISNPTRGTLYSFYCNASNELGWTISDRVVQGGAAYLDKSFQLVPQN-QSVDEGVNVTMRCRPPIGIPQPTIFWMREGKVIASQENLTDEPVKFSDYSNPFPSSAITITSKGYLQIYHIQSRDAGRYICGAKN 234

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. TrEMBL
Match: A0A068WBV4 (Roundabout 2 OS=Echinococcus granulosus OX=6210 GN=EgrG_000748500 PE=4 SV=1)

HSP 1 Score: 98.2117 bits (243), Expect = 4.042e-19
Identity = 58/175 (33.14%), Postives = 85/175 (48.57%), Query Frame = 1

Query:  172 DDYFPRSGSLKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKTGLSYLSPTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANN 696
            +D FP  G+L+  C   G P P I+WHD  T+  +  + A ++  +   G L I++P+ K TY  YCN SN   W+ S  V  GL+YL   +   P   + ++E   V+L CQ P GNP P T+W  +  EL        P      + E     + I+ +K   +G Y C A N
Sbjct:   37 EDTFPLEGNLEFSCKGTGFPEPQISWHDANTQKRLD-ESASNIHVNQYLGRLTIADPEVKRTYSVYCNISNTAGWVASSVVHGGLAYLEHDFPRFPID-KTVEEGDLVLLECQPPMGNPTPTTEWLFNNAEL--------PPGLGLISPEG---DLHIREVKSKHAGTYACRARN 198

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Cavefish
Match: pxdn (peroxidasin [Source:NCBI gene;Acc:103028918])

HSP 1 Score: 68.9366 bits (167), Expect = 1.133e-12
Identity = 64/237 (27.00%), Postives = 109/237 (45.99%), Query Frame = 1

Query:  154 RITRLSDDYFPRSG-SLKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDS-----EQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKTG---LSYLS----PTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEYFHLKSSASWVLVMNSFSDLIFDISIKQISQKTGDDVEMLCD 825
            RIT    D    SG ++   C AEGNP P I W        ++ ++A++++ D+     E G L+I + +      + C A N     V+  VKTG   L Y      P++ IQP++ ++L   QSV L C    G P P+  W +  R  L     +D +  I  +       + I+++  +D G+Y C A+N    + ++A   +++ +F    F +S +  S   G  V+  C+
Sbjct:  219 RITSEPQDVDVTSGNTVYFTCRAEGNPKPQIIW--------LRNNNALNMRDDTRLNLLEDGTLMIQDTRETDQGVYQCMAKN-----VAGEVKTGEVTLRYFGTPSRPSFVIQPQNTEVLVG-QSVTLECSAA-GQPQPRVSWTRGDRSPLP----NDARINITPSG-----GLYIQNVNQADGGQYTCFASNNVDTIHATA--YIIVQAFPQ--FTVSPQDQSVLEGHTVDFPCE 427

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Cavefish
Match: pxdn (peroxidasin [Source:NCBI gene;Acc:103028918])

HSP 1 Score: 68.5514 bits (166), Expect = 1.280e-12
Identity = 64/237 (27.00%), Postives = 109/237 (45.99%), Query Frame = 1

Query:  154 RITRLSDDYFPRSG-SLKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDS-----EQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKTG---LSYLS----PTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEYFHLKSSASWVLVMNSFSDLIFDISIKQISQKTGDDVEMLCD 825
            RIT    D    SG ++   C AEGNP P I W        ++ ++A++++ D+     E G L+I + +      + C A N     V+  VKTG   L Y      P++ IQP++ ++L   QSV L C    G P P+  W +  R  L     +D +  I  +       + I+++  +D G+Y C A+N    + ++A   +++ +F    F +S +  S   G  V+  C+
Sbjct:  243 RITSEPQDVDVTSGNTVYFTCRAEGNPKPQIIW--------LRNNNALNMRDDTRLNLLEDGTLMIQDTRETDQGVYQCMAKN-----VAGEVKTGEVTLRYFGTPSRPSFVIQPQNTEVLVG-QSVTLECSAA-GQPQPRVSWTRGDRSPLP----NDARINITPSG-----GLYIQNVNQADGGQYTCFASNNVDTIHATA--YIIVQAFPQ--FTVSPQDQSVLEGHTVDFPCE 451

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Cavefish
Match: ENSAMXT00000007998.2 (hemicentin-2-like [Source:NCBI gene;Acc:103025576])

HSP 1 Score: 63.929 bits (154), Expect = 4.450e-11
Identity = 52/213 (24.41%), Postives = 98/213 (46.01%), Query Frame = 1

Query:  184 PRSGSLKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKTGLSYLSPTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEYFHLKSSASWVLVMNSFSDLIFDISIKQISQKTGDDVEMLC 822
            P      L CV +G P P + W   K   ++      DL+ D +  LL+     P+    ++C A+N+K  + S+      + +  T+ +QP + + +++  SV LSC+ P   PP +  WFK+ R LL+        R   S    G+  +  + ++ +D G Y C A+N Y   ++  S  + ++  +     I    ++   G++V++ C
Sbjct:  243 PAETEAALHCVVQGFPAPAVQWF--KDGQVLPNTSRWDLQDDGQ--LLVFERVLPEDEGFYHCEANNEKERLRSRPAYLLPAVMDWTFVLQPVN-KTVRKGDSVTLSCRPPHSRPPAQVSWFKNNR-LLR-------PRPHLSMEPAGD--LLFRSVQETDRGYYFCRASNSYLQ-RAVTSRKIFLDVLAPPSVTIWPLVVTSTVGEEVQIQC 439

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Cavefish
Match: cntn3a.1 (contactin 3a, tandem duplicate 1 [Source:ZFIN;Acc:ZDB-GENE-081030-10])

HSP 1 Score: 63.1586 bits (152), Expect = 7.843e-11
Identity = 57/216 (26.39%), Postives = 92/216 (42.59%), Query Frame = 1

Query:  196 SLKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNP--QPKITYEFYCNASNDKTWIVSKSVKTGLSYLSPTYKIQ-PESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEYFHLKSSASWVL--VMNSFSDLIFDISIKQISQKTGDDVEMLCDP 828
            ++KL C A GNP+P I+W         +       K D  +   ++  P  Q +   ++ C A N +       VK  LS+ +P + ++ P+  Q   +  S++  C+   G P P  KW K+           DP        +  N ++ I  L LSD+G Y C+A N Y  + ++A   +  V   FSD +      Q   + G DV + C P
Sbjct:  254 TVKLECFALGNPVPAISWRRVDGAPFPR-------KVDVSRASSVLEIPYFQQEDAGQYECVAENSRG---RNMVKGKLSFYAPPHLLERPQDTQKAID-DSLVWECK-ASGKPKPSYKWLKN----------GDPLEAFEDRMQVVNGALSISSLTLSDTGMYQCVAENRYGRVFANAELKVNAVAPDFSDSVLK---AQTLARQGGDVLIECRP 444

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Cavefish
Match: ENSAMXT00000045031.1 (pep primary_assembly:Astyanax_mexicanus-2.0:3:67821576:67829689:1 gene:ENSAMXG00000032553.1 transcript:ENSAMXT00000045031.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 59.6918 bits (143), Expect = 3.197e-10
Identity = 51/190 (26.84%), Postives = 83/190 (43.68%), Query Frame = 1

Query:  193 GSLKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKTGLSYL---------SPTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANN--------EYFHL 711
            GS+ L C +EG P P++ WH    K      +++  +  S   L I+   QP  T  + C A+N      S SV+  L+ L         SP + ++P    ++    +V+L+CQ   G P P  +W    R LL      + +  I +N      S++I   +  D+ EY C+A N        +Y H+
Sbjct:   41 GSVTLQCQSEGYPTPSVIWH----KDGQPLTESVRQRVLSSGSLHIVFT-QPGDTGRYTCTAANVAG---SSSVEMSLTVLNSQPSLFSGSPIFTVEPFD-TVVDSGSTVVLNCQA-QGEPTPVIEWASQGRPLLS-----NDRITILANG-----SLRISSAQKEDTAEYACIARNLMGSALDYDYLHI 210

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Sea Lamprey
Match: pxdn (peroxidasin [Source:ZFIN;Acc:ZDB-GENE-140415-2])

HSP 1 Score: 66.6254 bits (161), Expect = 1.249e-12
Identity = 62/208 (29.81%), Postives = 92/208 (44.23%), Query Frame = 1

Query:  133 ASFFH--TIRITRLSDDYFPRSG-SLKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKTGLSYLS----PTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEYFHLKSSASWVL 735
            A  FH  + RIT    D     G ++ L C AEGNP P I W     +  M  D+  +L  D   G L+I + +      + C A N    +  K+ +  L Y      PT+ IQP   ++L   +SV L C    G+P P+  W +D  E L      DP+   FS    G   + ++     D G Y C A+N    +++SA+ +L
Sbjct:  175 AQEFHCESPRITSEPHDVDVTPGNTVYLRCRAEGNPKPAIIWLHNSNEIAMAEDERRNLLQD---GTLMIRDTRHTDQGTYQCMARNVAGEV--KAPEVVLRYFDVPAPPTFVIQPHDTEVLVG-ESVTLECS-AGGHPAPRVSWTRDDSEQLP----ADPR---FSVTASG--GLHVERAGPGDEGRYTCHASNNQDSIRASATILL 366

HSP 2 Score: 59.6918 bits (143), Expect = 2.520e-10
Identity = 53/214 (24.77%), Postives = 96/214 (44.86%), Query Frame = 1

Query:  196 SLKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTD-----SEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKTGLSYLSPTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEYFHLKSSASWVLVMNSFSDLIFDISIKQISQKTGDDVEMLC 822
            S+ L C A G+P P ++W           DD+  L  D     +  G L +    P     + C+ASN++  I  ++  T L   +P + + PE  Q++ E  +V L C+   G P P   W K   +L       D +  + S+      +++I  + L D G++ C A N    ++ +A+ + V+   +  +F ++   I+  +G DV + C
Sbjct:  295 SVTLECSAGGHPAPRVSW---------TRDDSEQLPADPRFSVTASGGLHVERAGPGDEGRYTCHASNNQDSI--RASATILLKSAPQFILAPED-QVVTEGHTVDLHCE-AQGRPLPVIAWTKAGSQL-----PSDRRLTVLSSG-----TLRIARVALHDQGQFECQAVN-VVGVRRAATQLTVLPRVTP-VFSVTPSDITTDSGRDVRIAC 483

HSP 3 Score: 49.6766 bits (117), Expect = 4.035e-7
Identity = 47/186 (25.27%), Postives = 78/186 (41.94%), Query Frame = 1

Query:  196 SLKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKTGLSYLSPTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEYFHLKSSASWVLVMNSFS 753
            ++ L C A+G P+P I W  TK  S +  D  +   T    G L I+        +F C A N      + +  T L  ++P + + P  I      + V ++C    G P P   W KD   +       +  +F  S   +    ++I+    +D G Y C+A N   H  +S S +L + +F+
Sbjct:  386 TVDLHCEAQGRPLPVIAW--TKAGSQLPSDRRL---TVLSSGTLRIARVALHDQGQFECQAVNVVGVRRAATQLTVLPRVTPVFSVTPSDITT-DSGRDVRIACS-AQGEPQPSLMWAKDGVHI------TESGKFHVSAEGY----LEIRDAGPADQGRYECIARNSIGH--ASTSMLLSVTAFT 552

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002502.1 (pep scaffold:Pmarinus_7.0:GL476400:249000:366561:-1 gene:ENSPMAG00000002253.1 transcript:ENSPMAT00000002502.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 57.3806 bits (137), Expect = 1.568e-9
Identity = 61/220 (27.73%), Postives = 86/220 (39.09%), Query Frame = 1

Query:  196 SLKLICVAEGNPMPTITWHD-------TKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKTGLSYLSPTYKIQPESIQILKEFQSVILSCQLPD----GNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEYFHLKSSASWVLVMNSFSDLIFDISIKQISQKTGDDVEMLC 822
            S+   C   G P   +TW+         K K++ Q++ A          +L + N +      + C A N        S KT  S      K  P   ++LK  Q VI  C   D    G PP    WF    EL  YS   D     F +N     S+ I  LK+SD+GEY C  +NE   +  SA  + V    +   FD  ++ +    GD  E+ C
Sbjct: 6640 SVYFECQVAGAPEIRVTWYKGSQKLSGAKYKTMFQHNTA----------VLEVKNFEKADVGTYSCEAENSL-----GSAKTSASLAGKERKHPPSFSRMLKNMQQVIGDCAKFDARVTGTPPFHVSWFLGDSEL-SYS---DKHVISFEDNV---ASLSIFSLKVSDAGEYTCKVSNEDGSISCSAK-LDVTERKTKPTFDQKLEPVEAVVGDPAELEC 6836

HSP 2 Score: 51.9878 bits (123), Expect = 8.978e-8
Identity = 44/168 (26.19%), Postives = 82/168 (48.81%), Query Frame = 1

Query:  193 GSLKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKTGLSYLSPTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANN 696
            G + L C  +G+P+  +TW   K  + ++ D  + L   +   +L I + + + + ++ C A N+    VS +    +  + P++K   ES+++ +    V L  +L DG+PP   KW K+ REL K     D  R   +  E+   +++I +   +D G+Y C   N
Sbjct: 4358 GLVHLDCSLKGSPVIKVTWF--KNDNEVKADGRVQLSFVNNVAVLEIRDSETEDSADYTCEAQNE-VGTVSCTCAVSVKEI-PSFKKPLESMEV-RGNSDVTLEVEL-DGSPPFDVKWVKNARELPKI----DKYR---AKLENTTATLRIGNFSAADVGQYSCKVKN 4512

HSP 3 Score: 51.6026 bits (122), Expect = 1.320e-7
Identity = 48/200 (24.00%), Postives = 87/200 (43.50%), Query Frame = 1

Query:  154 RITRLSDDYFPRSGSLKLI-CVAEGNPMPTITWHDTKTKSLMQYDDAMDLK--------TDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKTGLSYLSPTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEYFHLKSSAS 726
            +I + ++D F   G   +  C+  G+P P++TW     +S M     +D+         +D+     +  N    +  E  C ++         SV   +S   P + ++P + + + E  ++I  C++  G PPP+  W KD+R +        P   +    E  +  +QIK +K +D+G Y C A N     KS A+
Sbjct: 2650 QIIKATEDMFCIEGDDAMFECLVFGDPEPSVTWAKEMGRSTMFMKAGVDISWLSTLSRASDAGDYSCVAKN----VVGEVECCSALFVEMPAESSVDNKVSETPPAF-LKPLTGKKVYENGTLIFVCEVV-GKPPPEVLWMKDRRLI-------QPLSNVVMEQEGCHYILQIKDVKPTDAGVYVCEATNFIGEAKSFAN 2836

HSP 4 Score: 50.447 bits (119), Expect = 2.851e-7
Identity = 51/208 (24.52%), Postives = 82/208 (39.42%), Query Frame = 1

Query:  166 LSDDYFPRSGSLKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGL--LIISNPQPKITYEFYCNASNDKTWIVSKS-------------------VKTGLSYLSPTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRF-IFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEYFHLKSSA 723
            L D       S+++ C   G P P I W     +   + + + D +   + G+  L I     + +  F C A+N+   + + S                     TG   ++P Y +Q    Q L E  SV+  CQ+  G+P P   W K    L         +R+ +  N E G CS++I      D+GEY C+  N+     +SA
Sbjct:  383 LKDTTVVEGESVRMECQVAGFPTPAIMWF----REEYRIERSADFQIAFQAGVASLTIREAFAEDSGRFTCTATNEAGTVSTSSYLLVQGEESIFLEDSEASGTDTGGDGIAP-YFVQKPQPQHLVEGGSVVFHCQI-KGSPKPHVYWKKSGIPL----TTGYRRRYKVHYNKETGECSLEISMTFSDDAGEYTCVVRNKQGDAAASA 580

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004605.1 (pep scaffold:Pmarinus_7.0:GL476854:241038:246210:-1 gene:ENSPMAG00000004199.1 transcript:ENSPMAT00000004605.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 55.4546 bits (132), Expect = 3.771e-9
Identity = 52/226 (23.01%), Postives = 88/226 (38.94%), Query Frame = 1

Query:  169 SDDYFPRSGSLKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGL--LIISNPQPKITYEFYCNASN---DKTWIVSKSVKTGLSYLSPTYKIQPE-SIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEYFHLKSSASWVL-VMNSFSDLIF-DISIKQISQKTGDDVEMLC 822
             D   P  G+L+L CVAEG P P + W           D  M +  D    L  ++ S+        + C   N   + +   + S+       +P  + +PE ++  +    S+ L C+   G+P P   W      L   S+     R +     H N S++I+    SD+G Y C+A        +  S  L VM + +   F   + +++    G  V + C
Sbjct:  109 GDVAVPYGGALRLRCVAEGEPRPVVVWRLPSASPPPSADRRMRVLPDGSLALDGVVASD-----AGRYVCTVRNRHGEDSATATVSINQ-----APQIQDKPERAVVRITSGDSIALECRA-SGDPAPLITW-----RLPDGSVPHSSGRLL----THANGSLEIRSAARSDAGRYACVARGADGSRDARLSVDLTVMGAPAPPSFLAPTTERVEVAPGASVALAC 314

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004023.1 (pep scaffold:Pmarinus_7.0:GL478897:537:36338:-1 gene:ENSPMAG00000003678.1 transcript:ENSPMAT00000004023.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 53.9138 bits (128), Expect = 1.144e-8
Identity = 47/204 (23.04%), Postives = 88/204 (43.14%), Query Frame = 1

Query:  151 IRITRLSDDYFPRSGSLKLICVAEGNPMPTITWH----DTKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKTGLSYLSPTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEYFHLKSSASWVLVMNSF 750
            I ++  S  +  R    +L C A GNP+P I+W     D  TK ++   +A          +L + N QP+ T  + C A+N        + +  ++  +P   ++P S        ++   C+   G P P  KW KD        +  + +  +  + +     + + ++K SD G + C+A N++  + SSA   +  N+F
Sbjct:  168 IEVSFPSKTHVLRGDMARLECFALGNPVPRISWRKIDGDLPTKVVLSKSNA----------VLELPNVQPEDTGSYECKAANSAG---RNTAQGKITVYAPPQWLEPISDVEQGLGDTLQWECKA-TGKPQPAYKWMKD-----GVLVGAEGRVRVLESGD-----LIVGNVKPSDRGMFQCVAENKHGRIYSSAELRVRGNAF 347

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010567.1 (pep scaffold:Pmarinus_7.0:GL479154:561817:685780:1 gene:ENSPMAG00000009565.1 transcript:ENSPMAT00000010567.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 53.9138 bits (128), Expect = 1.740e-8
Identity = 43/181 (23.76%), Postives = 75/181 (41.44%), Query Frame = 1

Query:  169 SDDYFPRSGSLKLICVAEGNPMPTITWHDTKTKSLMQYDDA----MDLKTDSEQGLLIISNPQPKITYEFY-CNASNDKTWIVSKSVKTGLSYLSPTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANN 696
            SD    R     L C AEG P PT+ W+    +     DD     M L T S   L I+   + K     Y C A N     VS++    ++ +   Y+  P ++++    +  ++ C+ P G+P P   W ++       ++ D  +R      +     + I + + +D+G Y C+  N
Sbjct:   37 SDLIVSRGEPATLNCKAEGRPAPTVEWYKDGERVETDRDDPRSHRMLLPTGSLFFLRIVHGRRTKTDEGSYVCVARNYLGEAVSRNASLEVANIRRNYRSSPSAVKVAAR-EPAVMECRPPRGHPEPTVSWKRN-----GVALTDKDERVTIRGGK-----LMISNTQKADAGMYVCVGTN 206

HSP 2 Score: 51.9878 bits (123), Expect = 7.423e-8
Identity = 42/174 (24.14%), Postives = 81/174 (46.55%), Query Frame = 1

Query:  223 GNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKTGLSYLSPTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLK---YSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEYFHLKSSASWVL 735
            G+P PT++W      +L   D+ + ++     G L+ISN Q      + C  +N      S+  +  + +  PT+  +P ++ +L +       C++  G+PPP  +W K+  +L K   + IQDD              +++++ +  +D G Y C+  N     ++SAS V+
Sbjct:  158 GHPEPTVSWKRNGV-ALTDKDERVTIRG----GKLMISNTQKADAGMYVCVGTNMVGERDSEPAELAV-FERPTFARKPMNLVMLAD-SDAEFRCEV-HGDPPPTVRWRKEDGDLPKGSRFEIQDD-------------YTLRVERVGGTDEGTYTCVGENRVGKAEASASLVV 310

HSP 3 Score: 47.7506 bits (112), Expect = 1.650e-6
Identity = 45/184 (24.46%), Postives = 75/184 (40.76%), Query Frame = 1

Query:  157 ITRLSDDYFPRSGSLKLICVAEGNPMPTITWHDTKTKSLM---QYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKS---VKTGLSYLSPTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLA 690
            + R  D    +  S   +C   GNP P + W    +++L+   Q        + S+ G L I++ Q   +  + C A +    I++K+   V   L+   P    Q  + Q L      +L+CQ   G P P   W KD  +L   S +                ++ IK ++L D+G Y C+A
Sbjct:  317 VVRPRDQIVAQGQSATFLCETTGNPPPAVFWQREGSQNLLFPNQPSQPSSRFSVSQTGHLTITDVQRSDSGYYTCQALSVAGSILAKALLEVGDALADSPPPIIRQGPANQTLAVGSVALLACQ-AMGMPTPSVHWLKDGSKLSLGSAR---------LGLQSGGTLSIKDVQLMDAGLYTCVA 490

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Nematostella
Match: EDO45383 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RT26])

HSP 1 Score: 59.3066 bits (142), Expect = 4.370e-10
Identity = 51/164 (31.10%), Postives = 75/164 (45.73%), Query Frame = 1

Query:  199 LKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKTGLSYLSPTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLA 690
            +K  C   GNP P +TW     KS    + ++D +  S   +L+I+N     +  + CNASN+   I+S      + Y  P +   P+  +   E  SV   C    GNPPP   W K+   L   +   DP RF +SN  H    + I ++  +DSG Y C A
Sbjct:   14 VKFECQTTGNPSPNVTW----LKSGSAVNTSVDPRFYSNDTILMITNVSRIDSGTYSCNASNE-LGIISAEAALDVRY-GPEFVNVPQD-KTPNEGWSVTFECHT-KGNPPPTVTWLKNGSAL---NTSVDP-RF-YSNGTH----LMITNVNRTDSGAYRCNA 160

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Nematostella
Match: EDO49556 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGM0])

HSP 1 Score: 56.225 bits (134), Expect = 5.457e-9
Identity = 58/196 (29.59%), Postives = 90/196 (45.92%), Query Frame = 1

Query:  130 NASFFHTIRITRLSDDYFPRSG-SLKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKTGLSYLSPTYKIQPE-SIQILKEFQSVILSCQLPDGNPPPKTKWFKDQREL-----LKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANN 696
            N      I I  L+D+     G S++L CV  G P   + W+  K   L++ D+ +   TD +Q  LII + +     E+ C  +N      S  VKT L  ++P ++ +PE S   +     V L   +  G P PK +WFKD + +     L+   +DD         EH   S++IK  K  DSG+Y  +A +
Sbjct:   65 NVDISAPIIIKPLNDEIDVLEGDSVRLECVISGGPDAQVLWY--KDDYLLEEDERIMYDTDGDQHTLIIQSAELDDEAEYKCVVTN---IAGSVDVKTEL-IIAPEFQKEPEKSTFDVNTGDDVSLDLTVT-GKPTPKVEWFKDDKPVKGTRRLEVKAKDD---------EH---SLKIKGGKPDDSGKYTVVAES 241

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Nematostella
Match: EDO46961 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RNP0])

HSP 1 Score: 55.8398 bits (133), Expect = 8.522e-9
Identity = 50/178 (28.09%), Postives = 84/178 (47.19%), Query Frame = 1

Query:  193 GSLKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKI---TYEFYCNASN-------DKTWIVSKSVKTGLSYLSPTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANN 696
            G + +IC   G+PMPT+TW+  K  S+++ +  + + T    GL+ I   + KI   TYE  C A N       D + ++  +  T  +   P     P S +  +    V  +C    G P P   WFKD+  +    + +DP+  + S+       ++I  L+ SD+G+Y C+A N
Sbjct:   16 GFVYMICNVTGSPMPTLTWY--KNGSVIR-NSRIQIFTMPYGGLIRIGPLRAKIHKATYE--CEADNGVGPPLRDSSTLIVHTASTKPAGF-PRIAKHP-SFKQRRSGDDVTFTCAAV-GTPTPNITWFKDRLPI----VLNDPRVSVLSDGR----KLRITDLRESDNGKYSCVARN 177

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Nematostella
Match: EDO36120 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SJL2])

HSP 1 Score: 54.299 bits (129), Expect = 2.054e-8
Identity = 43/176 (24.43%), Postives = 76/176 (43.18%), Query Frame = 1

Query:  187 RSGSLKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKTGLSYLSPT--YKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEYFH 708
            +S S KL C  EG P P +TW  T+ K L +       +    QG+L +++P  +    + C AS+    +++ ++   +   S     K+ P +++I      +IL+C    G P P   W+KD   L        P + +   +E       I+    +D G+Y C A  ++  
Sbjct:  437 QSTSTKLECKVEGYPEPVVTWRRTRDKKLSEE------RHKVVQGVLYLNDPNKEDEGLYICRASSPMGSVIA-AIDVTVERFSAVKFLKVAPATLKIKNVNTPIILNCTA-KGTPSPTLTWYKDDVAL--------PTKILKDEDEF-TAVYTIQRPSSADQGKYFCAAKTKFLE 595

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Nematostella
Match: EDO35240 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SM31])

HSP 1 Score: 51.9878 bits (123), Expect = 3.398e-8
Identity = 50/179 (27.93%), Postives = 80/179 (44.69%), Query Frame = 1

Query:  220 EGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKTGLSYLSPTYKIQPESIQ-----ILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEYFHLKSSASWVLVM 741
            +G P PT+TW    TK+ +   D + ++  S  G L+IS  Q      + C A+N      S+           T K +PE IQ     ++ E  + + +C+   G+P P   W K  +    + +QD  + F+ SN E     ++I  +K  D GEY C A +      SSA  +L +
Sbjct:   28 KGRPAPTVTWLKN-TKAYV--PDGVRIQKVSP-GNLVISIAQKADMGTYQCVAANAVGRRKSRVATV-------TIKAKPEIIQRPKDVVIVEGNTALFTCKA-TGSPLPTVFWEKKSKGQPMFPMQDYGRFFVSSNGE-----LRISSVKKEDEGEYVCSALSPAGLGASSARAMLTV 189

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Medaka
Match: cntn4 (contactin-4-like [Source:NCBI gene;Acc:101167031])

HSP 1 Score: 67.781 bits (164), Expect = 2.709e-12
Identity = 59/218 (27.06%), Postives = 96/218 (44.04%), Query Frame = 1

Query:  178 YFPRSGSLKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKTGLSYLSPTYKIQ-PESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEYFHLKSSASWVLVMNSFSDLIFDISIKQISQKTGDDVEMLCDP 828
            +  +  ++KL C A GNP P+ITW         +  D     T    G+L I   Q      + C A N +       VK  LS+ +P + I+ P+ +Q L +  S++  C+   G P P  +W K+   L     +   +R   +N       + I  L LSD+G Y C+A N++  + S+A  + V+ +  D   +    Q   K G D+ + C P
Sbjct:  240 HVAKGSTVKLECFALGNPAPSITWRREDGAPFPRKVD-----TRKTNGVLEIPYFQQDDVGTYECVAENSRGM---NKVKGKLSFYAPPHLIEKPQDVQKLID-DSLVWECK-ATGKPKPSYRWMKNGENL-----ESTEERIQVANG-----VLSISRLTLSDTGMYQCVAGNKHGEVYSNAE-LRVIAAAPDFSHNQLRSQTMVKVGGDMLVECRP 436

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Medaka
Match: cntn4 (contactin-4-like [Source:NCBI gene;Acc:101167031])

HSP 1 Score: 67.3958 bits (163), Expect = 3.199e-12
Identity = 59/218 (27.06%), Postives = 96/218 (44.04%), Query Frame = 1

Query:  178 YFPRSGSLKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKTGLSYLSPTYKIQ-PESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEYFHLKSSASWVLVMNSFSDLIFDISIKQISQKTGDDVEMLCDP 828
            +  +  ++KL C A GNP P+ITW         +  D     T    G+L I   Q      + C A N +       VK  LS+ +P + I+ P+ +Q L +  S++  C+   G P P  +W K+   L     +   +R   +N       + I  L LSD+G Y C+A N++  + S+A  + V+ +  D   +    Q   K G D+ + C P
Sbjct:  243 HVAKGSTVKLECFALGNPAPSITWRREDGAPFPRKVD-----TRKTNGVLEIPYFQQDDVGTYECVAENSRGM---NKVKGKLSFYAPPHLIEKPQDVQKLID-DSLVWECK-ATGKPKPSYRWMKNGENL-----ESTEERIQVANG-----VLSISRLTLSDTGMYQCVAGNKHGEVYSNAE-LRVIAAAPDFSHNQLRSQTMVKVGGDMLVECRP 439

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Medaka
Match: cntn3a.1 (contactin-4 [Source:NCBI gene;Acc:101159916])

HSP 1 Score: 67.3958 bits (163), Expect = 3.339e-12
Identity = 61/217 (28.11%), Postives = 96/217 (44.24%), Query Frame = 1

Query:  190 SGSLKLICVAEGNPMPTITWHDTKTKSLMQYDDA---MDLKTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKTGLS-YLSPTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEYFHLKSSASWVLVMNSFSDLIFDISIKQISQKTGDDVEMLCDP 828
            S ++KL C A GNP+P I+W         + DDA     +K +   G+L I   Q +    + C A N +      SV+  L+ Y SP   ++P+ +Q   +  +V+  C+   G P P  +W K+   L       DP        E  +  + I+ L L D G Y C+A N+Y  +  +A  + V+    D   ++   Q   + G DV M C P
Sbjct:  244 SSTVKLECFALGNPVPKISWR--------RLDDAPFGRKVKVNEAFGVLEIPYFQQENAGIYECLAENSRG---RNSVRGKLTFYASPQLIVKPQDVQKTID-DTVVWECK-ASGKPKPSYRWLKNGESL-------DPME---DRIEVNDGVLTIRSLNLVDVGMYQCVAENKYGRIFCNAQ-LRVLAIAPDFSQNLVKAQTLARQGGDVLMECKP 436

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Medaka
Match: pxdn (peroxidasin [Source:NCBI gene;Acc:101162089])

HSP 1 Score: 67.0106 bits (162), Expect = 4.597e-12
Identity = 52/188 (27.66%), Postives = 90/188 (47.87%), Query Frame = 1

Query:  196 SLKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDS-----EQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKTG---LSYLS----PTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEYFHLKSSA 723
            ++   C AEGNP P I W        ++ ++A++++ DS     E G L+I + +      + C A N     V+  VKT    L Y      P++ IQP++ ++L   +SV L C    G P P+  W K  R  L     +DP+  I ++       + I++++ +D G+Y C A+N    + ++A
Sbjct:  212 TVYFTCRAEGNPKPQIIW--------LRNNNALNMRDDSRLNLLEDGTLMIQDTRETDQGVYQCMAKN-----VAGEVKTSQVTLRYFGAPTRPSFVIQPQNTEVLVG-ESVTLECS-ATGQPQPRVSWTKGDRTPLP----NDPRITITTSG-----GLYIQNVQQADGGQYTCFASNNVDTIHATA 375

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Medaka
Match: pxdn (peroxidasin [Source:NCBI gene;Acc:101162089])

HSP 1 Score: 67.0106 bits (162), Expect = 5.005e-12
Identity = 52/188 (27.66%), Postives = 90/188 (47.87%), Query Frame = 1

Query:  196 SLKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDS-----EQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKTG---LSYLS----PTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEYFHLKSSA 723
            ++   C AEGNP P I W        ++ ++A++++ DS     E G L+I + +      + C A N     V+  VKT    L Y      P++ IQP++ ++L   +SV L C    G P P+  W K  R  L     +DP+  I ++       + I++++ +D G+Y C A+N    + ++A
Sbjct:  236 TVYFTCRAEGNPKPQIIW--------LRNNNALNMRDDSRLNLLEDGTLMIQDTRETDQGVYQCMAKN-----VAGEVKTSQVTLRYFGAPTRPSFVIQPQNTEVLVG-ESVTLECS-ATGQPQPRVSWTKGDRTPLP----NDPRITITTSG-----GLYIQNVQQADGGQYTCFASNNVDTIHATA 399

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Planmine SMEST
Match: SMESG000001429.1 (SMESG000001429.1)

HSP 1 Score: 529.635 bits (1363), Expect = 5.299e-180
Identity = 251/253 (99.21%), Postives = 252/253 (99.60%), Query Frame = 1

Query:   70 MWYFVILVIFYQHGFLKTWTNASFFHTIRITRLSDDYFPRSGSLKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKTGLSYLSPTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEYFHLKSSASWVLVMNSFSDLIFDISIKQISQKTGDDVEMLCDP 828
            MWYFVILVIFYQ GFLKTWTNASFFHTIRITRLSDDYFPRSGSLKLICVAEGNPMPTITWHD+KTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKTGLSYLSPTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEYFHLKSSASWVLVMNSFSDLIFDISIKQISQKTGDDVEMLCDP
Sbjct:    1 MWYFVILVIFYQQGFLKTWTNASFFHTIRITRLSDDYFPRSGSLKLICVAEGNPMPTITWHDSKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKTGLSYLSPTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEYFHLKSSASWVLVMNSFSDLIFDISIKQISQKTGDDVEMLCDP 253

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Planmine SMEST
Match: SMESG000066973.1 (SMESG000066973.1)

HSP 1 Score: 118.242 bits (295), Expect = 1.427e-29
Identity = 74/257 (28.79%), Postives = 131/257 (50.97%), Query Frame = 1

Query:   70 MWYFVILVIFYQHGFLKTWTNASFFHTIRITRLSDDYFPRSGSLKLICVAEGNPMPTITWHDTKTK----SLMQYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKTGLSYLSPTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGN--CSMQIKHLKLSDSGEYHCLANNEYFHLKSSASWVLVMNSFSDLIFDISIKQISQKTGDDVEMLC 822
            M+ ++I ++     FL   T+    +   IT +   YFPR G+L+L C A+G P P I+W+D ++K    + +  ++ + +        LII+ P+ +  Y+ YCNASN   + VS    TGL+YL+  ++  P   +       V LSC  P+G P P  KWFK+ R++   S      R++ +N    N    ++I++    DSG+Y+C A N +  ++S+ S + +   FS+  +    K++  +  +  E+ C
Sbjct:    1 MFSYLIQIVI----FLNYITDTLTINAPVITEMPKSYFPRYGTLELSCRADGEPAPDISWYDLQSKQKILNGIGINNPVQIMKAGPLSRLIITEPEAQHEYKVYCNASNSLGYAVSPPASTGLAYLNRNFQSNPAIEKEAYSGNDVELSCSPPEGRPYPTVKWFKNGRQITSASN----SRYLITNQPDLNQYSILKIRNPNKEDSGKYYCQAENAFSTVRSATSNLKI---FSNSKYYKMQKELKYRISNSAEIQC 246

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Planmine SMEST
Match: SMESG000066973.1 (SMESG000066973.1)

HSP 1 Score: 112.849 bits (281), Expect = 9.696e-28
Identity = 67/225 (29.78%), Postives = 117/225 (52.00%), Query Frame = 1

Query:  166 LSDDYFPRSGSLKLICVAEGNPMPTITWHDTKTK----SLMQYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKTGLSYLSPTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGN--CSMQIKHLKLSDSGEYHCLANNEYFHLKSSASWVLVMNSFSDLIFDISIKQISQKTGDDVEMLC 822
            +   YFPR G+L+L C A+G P P I+W+D ++K    + +  ++ + +        LII+ P+ +  Y+ YCNASN   + VS    TGL+YL+  ++  P   +       V LSC  P+G P P  KWFK+ R++   S      R++ +N    N    ++I++    DSG+Y+C A N +  ++S+ S + +   FS+  +    K++  +  +  E+ C
Sbjct:    1 MPKSYFPRYGTLELSCRADGEPAPDISWYDLQSKQKILNGIGINNPVQIMKAGPLSRLIITEPEAQHEYKVYCNASNSLGYAVSPPASTGLAYLNRNFQSNPAIEKEAYSGNDVELSCSPPEGRPYPTVKWFKNGRQITSASN----SRYLITNQPDLNQYSILKIRNPNKEDSGKYYCQAENAFSTVRSATSNLKI---FSNSKYYKMQKELKYRISNSAEIQC 218

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Planmine SMEST
Match: SMESG000018028.1 (SMESG000018028.1)

HSP 1 Score: 58.5362 bits (140), Expect = 1.677e-9
Identity = 51/185 (27.57%), Postives = 87/185 (47.03%), Query Frame = 1

Query:  199 LKLICVAEGNPMPTITWHDTKTKSLMQYDD----AMDLKTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKTGLSYLSPTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEYFHLKSSASWVLVM 741
            + L C A+G+PMP I W+    + +  Y D    +  L  D+E   + +      +   +YCNASN   W +S +    +++L+    I PES +     ++V++ C+ P G P P   W     +    +I+ + +  I  N   GN  ++I      DSG Y+CLA N +   + S S +L +
Sbjct:   43 VSLRCSAKGDPMPNIIWY-KDGQVVESYRDKPATSNRLVKDNELLFMHLDTQDEGV---YYCNASNIHGWTISNNASVLIAFLNKDI-IGPES-KTASVGETVLMECKPPKGVPKPTVIW-----KFNGNAIEVNKRIKILDN---GN--LRIDKATRKDSGRYNCLAKN-FADERDSTSALLTV 210

HSP 2 Score: 47.3654 bits (111), Expect = 8.013e-6
Identity = 58/246 (23.58%), Postives = 99/246 (40.24%), Query Frame = 1

Query:  109 GFLKTWTNASFFHTIRITRLSDDYFPRSGSLKLI-CVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQ----GLLIISNPQPKITYEFYCNASNDKTWIVSKS---VKTGLSYLSPTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHC-LANNEYFHLKSSASWVLVMNSFSDLIFDISIKQISQKTGDDVEML 819
            G L+ +   S   T       D+   R G   +  C   G+P PTI W       +   D+    +++  Q    G L I+  +   + ++ C AS+    I S +   V     Y+ P  ++ P++ Q L+   +   +CQ P         W K+  +L   ++  DP+    +  +     ++I  L++SD+G Y C +  NE F L S    +L  N +   I          +T DD  ML
Sbjct:  290 GHLEAYAKLSVVSTPGFIETPDNQKVRVGDTAIFNCRVTGSPQPTIIWSHNGDHFIA--DEENSRRSERIQVDKLGSLTINPVKISDSGKYECKASSYIGKIQSSASLHVIDAQKYVPPVIEVGPQN-QTLRIGLTATFNCQ-PKQQDDVTVHWLKNGHQL---NLVSDPRIITLTTGK-----LKINLLRMSDAGNYTCKIVQNEAFTLWSVTLKILDKNDYETAIM---------QTIDDARML 514

[Close]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Planmine SMEST
Match: SMESG000021248.1 (SMESG000021248.1)

HSP 1 Score: 55.8398 bits (133), Expect = 1.888e-8
Identity = 47/172 (27.33%), Postives = 81/172 (47.09%), Query Frame = 1

Query:  187 RSG-SLKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKTGLSYLSPTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNE 699
            RSG S  ++C AEG P P I W     K + +Y      KTDS  G+L I++ + + T  + C  +N    I   S    +  +SP     P+   +++  + V+L C + +G  P +  W+      +  +I  +  +F+   +E G   + I  ++   SG Y C+ANN+
Sbjct: 2445 RSGTSFSVLCTAEGYPKPVIKW-TRDGKGIFRY----GTKTDSRTGILEITDAKEEDTGRYTCTGTNK---ISQDSKSVDVVIISPPKIESPKKSIMVRVGEQVLLPC-IVEGTRPFRIHWYTPGNNQISSTILGE-YQFL---SEQG---LIIDRVRKDHSGVYRCVANND 2600

HSP 2 Score: 48.521 bits (114), Expect = 3.979e-6
Identity = 43/167 (25.75%), Postives = 75/167 (44.91%), Query Frame = 1

Query:  205 LICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKTGLSYLSPTYKIQPESIQ--ILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNE 699
            L C  +G+P P I W        M+    + +  D  Q  L + +   +    F C A+ND   +V K  K  +S  +P  +I  E I    +   ++V L+C +  GNP PK +W+K+ + L++      P R   +  ++    +++      ++G Y C A NE
Sbjct: 1026 LQCQTKGDPKPKIEWRKGGRPLTMEPGLRIVISPDGSQ--LTVYSITEEHAGTFTCTATNDHAAVV-KEFK--VSVKAPP-QISKEGISDYEIGSKENVELNCIITSGNPSPKIEWYKNGQPLVEI-----PGRVEIAGQKN---ILKVYGKNEDETGSYECKATNE 1178

HSP 3 Score: 47.3654 bits (111), Expect = 9.032e-6
Identity = 50/172 (29.07%), Postives = 77/172 (44.77%), Query Frame = 1

Query:  196 SLKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDLKTDSE-QGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKTGLS-YL---SPTYKIQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKRFIFSNNEHGNCSMQIKHLKLSDSGEYHCLANN 696
            ++ L C+A GNP P I W     K  +   +A+  K   E Q  LI+         E+ C A N+       S+ T  + Y+   +P   I    I +     ++  SC + +  PP + KWFK++ ++ K   +D   RF  S +       ++KHL   DSG Y CLA N
Sbjct: 1306 TITLTCIASGNPTPKIKWL---FKKKLIPPNAVGYKMVGENQETLIVERAASMHGGEYSCLAENEGGKDQKNSIVTVFAPYIDMKTPNKNITYNPIIV---GGNITFSCVM-NSTPPAEIKWFKNEIDIYKSLPKD---RFKISLDGSTLTLFEVKHL---DSGIYKCLAIN 1464

The following BLAST results are available for this feature:

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Human
BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Celegans
BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Fly
BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Zebrafish
BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Xenopus
BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Mouse
BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. UniProt/SwissProt
BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. TrEMBL
BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Cavefish
BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Sea Lamprey
BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Yeast
BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Nematostella
BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Medaka
BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Planmine SMEST

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
PXDN	4.583e-14	30.77	peroxidasin [Source:HGNC Symbol;Acc:HGNC:14966]	[more]
PXDN	5.673e-14	31.82	peroxidasin [Source:HGNC Symbol;Acc:HGNC:14966]	[more]
CNTN4	4.876e-12	30.77	contactin 4 [Source:HGNC Symbol;Acc:HGNC:2174]	[more]
HMCN1	1.043e-11	27.54	hemicentin 1 [Source:HGNC Symbol;Acc:HGNC:19194]	[more]
CNTN4	1.611e-11	30.77	contactin 4 [Source:HGNC Symbol;Acc:HGNC:2174]	[more]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
sax-3	1.002e-11	27.37	pep chromosome:WBcel235:X:3451945:3465925:-1 gene:...	[more]
sax-3	1.050e-11	27.37	pep chromosome:WBcel235:X:3451945:3465925:-1 gene:...	[more]
unc-89	1.939e-9	25.39	Muscle M-line assembly protein unc-89 [Source:Uni...	[more]
unc-89	2.336e-9	25.39	Muscle M-line assembly protein unc-89 [Source:Uni...	[more]
unc-89	2.458e-9	25.39	Muscle M-line assembly protein unc-89 [Source:Uni...	[more]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
robo3	1.171e-11	25.38	gene:FBgn0041097 transcript:FBtr0077921	[more]
robo3	1.171e-11	25.38	gene:FBgn0041097 transcript:FBtr0335384	[more]
robo2	5.123e-11	23.12	gene:FBgn0002543 transcript:FBtr0329985	[more]
robo2	6.121e-11	23.12	gene:FBgn0002543 transcript:FBtr0077941	[more]
robo1	4.456e-10	26.13	gene:FBgn0005631 transcript:FBtr0071922	[more]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
cntn3b	1.898e-11	23.97	contactin 3b [Source:ZFIN;Acc:ZDB-GENE-130530-645]	[more]
cntn4	4.094e-11	26.94	contactin 4 [Source:ZFIN;Acc:ZDB-GENE-060929-776]	[more]
cntn4	9.618e-11	26.94	contactin 4 [Source:ZFIN;Acc:ZDB-GENE-060929-776]	[more]
cntn4	9.995e-11	26.94	contactin 4 [Source:ZFIN;Acc:ZDB-GENE-060929-776]	[more]
cntn4	1.008e-10	26.94	contactin 4 [Source:ZFIN;Acc:ZDB-GENE-060929-776]	[more]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
cep131	1.998e-12	26.01	centrosomal protein 131kDa [Source:Xenbase;Acc:XB-...	[more]
polr1e	9.200e-12	30.05	polymerase (RNA) I polypeptide E [Source:Xenbase;A...	[more]
polr1e	9.635e-12	30.05	polymerase (RNA) I polypeptide E [Source:Xenbase;A...	[more]
polr1e	9.701e-12	30.05	polymerase (RNA) I polypeptide E [Source:Xenbase;A...	[more]
polr1e	9.712e-12	30.05	polymerase (RNA) I polypeptide E [Source:Xenbase;A...	[more]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Pxdn	4.506e-14	31.28	peroxidasin [Source:MGI Symbol;Acc:MGI:1916925]	[more]
Robo4	5.084e-14	26.05	roundabout guidance receptor 4 [Source:MGI Symbol;...	[more]
Pxdn	5.237e-14	31.28	peroxidasin [Source:MGI Symbol;Acc:MGI:1916925]	[more]
Cntn4	1.503e-12	28.25	contactin 4 [Source:MGI Symbol;Acc:MGI:1095737]	[more]
Robo4	2.224e-12	27.80	roundabout guidance receptor 4 [Source:MGI Symbol;...	[more]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q92626\|PXDN_HUMAN	2.724e-13	31.82	Peroxidasin homolog OS=Homo sapiens OX=9606 GN=PXD...	[more]
sp\|Q3UQ28\|PXDN_MOUSE	3.663e-13	31.28	Peroxidasin homolog OS=Mus musculus OX=10090 GN=Px...	[more]
sp\|Q80W87\|ROBO4_RAT	6.221e-13	27.32	Roundabout homolog 4 OS=Rattus norvegicus OX=10116...	[more]
sp\|Q8C310\|ROBO4_MOUSE	1.674e-11	27.80	Roundabout homolog 4 OS=Mus musculus OX=10090 GN=R...	[more]
sp\|Q62682\|CNTN3_RAT	3.290e-11	28.18	Contactin-3 OS=Rattus norvegicus OX=10116 GN=Cntn3...	[more]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A0R3U7X5	4.815e-20	30.91	Uncharacterized protein OS=Mesocestoides corti OX=...	[more]
A0A5K3FNC5	5.433e-20	30.91	Uncharacterized protein OS=Mesocestoides corti OX=...	[more]
A0A068Y9I9	1.542e-19	33.14	Roundabout 2 OS=Echinococcus multilocularis OX=621...	[more]
A0A504YEM6	1.730e-19	30.10	Uncharacterized protein OS=Fasciola gigantica OX=4...	[more]
A0A068WBV4	4.042e-19	33.14	Roundabout 2 OS=Echinococcus granulosus OX=6210 GN...	[more]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
pxdn	1.133e-12	27.00	peroxidasin [Source:NCBI gene;Acc:103028918]	[more]
pxdn	1.280e-12	27.00	peroxidasin [Source:NCBI gene;Acc:103028918]	[more]
ENSAMXT00000007998.2	4.450e-11	24.41	hemicentin-2-like [Source:NCBI gene;Acc:103025576]	[more]
cntn3a.1	7.843e-11	26.39	contactin 3a, tandem duplicate 1 [Source:ZFIN;Acc:...	[more]
ENSAMXT00000045031.1	3.197e-10	26.84	pep primary_assembly:Astyanax_mexicanus-2.0:3:6782...	[more]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
pxdn	1.249e-12	29.81	peroxidasin [Source:ZFIN;Acc:ZDB-GENE-140415-2]	[more]
ENSPMAT00000002502.1	1.568e-9	27.73	pep scaffold:Pmarinus_7.0:GL476400:249000:366561:-...	[more]
ENSPMAT00000004605.1	3.771e-9	23.01	pep scaffold:Pmarinus_7.0:GL476854:241038:246210:-...	[more]
ENSPMAT00000004023.1	1.144e-8	23.04	pep scaffold:Pmarinus_7.0:GL478897:537:36338:-1 ge...	[more]
ENSPMAT00000010567.1	1.740e-8	23.76	pep scaffold:Pmarinus_7.0:GL479154:561817:685780:1...	[more]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO45383	4.370e-10	31.10	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO49556	5.457e-9	29.59	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO46961	8.522e-9	28.09	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO36120	2.054e-8	24.43	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO35240	3.398e-8	27.93	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
cntn4	2.709e-12	27.06	contactin-4-like [Source:NCBI gene;Acc:101167031]	[more]
cntn4	3.199e-12	27.06	contactin-4-like [Source:NCBI gene;Acc:101167031]	[more]
cntn3a.1	3.339e-12	28.11	contactin-4 [Source:NCBI gene;Acc:101159916]	[more]
pxdn	4.597e-12	27.66	peroxidasin [Source:NCBI gene;Acc:101162089]	[more]
pxdn	5.005e-12	27.66	peroxidasin [Source:NCBI gene;Acc:101162089]	[more]

BLAST of Roundabout, axon guidance receptor, homolog 2 (Drosophila) vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000001429.1	5.299e-180	99.21	SMESG000001429.1	[more]
SMESG000066973.1	1.427e-29	28.79	SMESG000066973.1	[more]
SMESG000066973.1	9.696e-28	29.78	SMESG000066973.1	[more]
SMESG000018028.1	1.677e-9	27.57	SMESG000018028.1	[more]
SMESG000021248.1	1.888e-8	27.33	SMESG000021248.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30019296 ID=SMED30019296|Name=Roundabout, axon guidance receptor, homolog 2 (Drosophila)|organism=Schmidtea mediterranea sexual|type=transcript|length=851bp
AAAACTTTGAAATTATCAAAAAATGCCATACAATTTATCAAAATTAATAA
TAAAATCGTTAAGAAAAGAATGTGGTATTTTGTGATTTTAGTCATCTTTT
ATCAACATGGATTTCTAAAAACTTGGACAAATGCTTCATTTTTTCACACA
ATAAGGATAACACGACTATCAGATGACTACTTTCCAAGATCTGGCAGCCT
TAAATTAATTTGCGTTGCTGAAGGTAATCCAATGCCAACTATTACTTGGC
ATGACACTAAAACGAAATCTCTGATGCAATATGATGATGCGATGGATCTA
AAAACCGACTCAGAACAAGGTTTATTAATCATTAGTAATCCTCAACCAAA
AATAACTTATGAATTTTACTGCAATGCCAGTAATGATAAAACCTGGATTG
TGAGCAAATCTGTGAAAACAGGTCTGTCGTATTTATCTCCAACCTACAAA
ATCCAACCAGAAAGTATTCAAATATTAAAAGAATTTCAATCAGTAATTCT
TTCTTGCCAATTACCGGACGGTAATCCTCCCCCCAAAACCAAATGGTTCA
AAGATCAAAGAGAATTGTTGAAATATTCTATTCAAGATGATCCCAAAAGA
TTTATCTTTTCTAACAATGAACATGGTAACTGTTCCATGCAAATCAAACA
CTTAAAGCTCTCTGATTCCGGCGAATATCACTGTCTTGCTAATAATGAAT
ATTTTCACTTAAAATCTTCTGCCTCGTGGGTGTTGGTAATGAATTCTTTC
AGCGACTTAATTTTCGATATCTCAATCAAACAGATTTCGCAGAAAACTGG
AGATGACGTGGAAATGCTTTGCGATCCAAATAATAATAATAATAACAATA
A

protein sequence of SMED30019296-orf-1

>SMED30019296-orf-1 ID=SMED30019296-orf-1|Name=SMED30019296-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=283bp
KTLKLSKNAIQFIKINNKIVKKRMWYFVILVIFYQHGFLKTWTNASFFHT
IRITRLSDDYFPRSGSLKLICVAEGNPMPTITWHDTKTKSLMQYDDAMDL
KTDSEQGLLIISNPQPKITYEFYCNASNDKTWIVSKSVKTGLSYLSPTYK
IQPESIQILKEFQSVILSCQLPDGNPPPKTKWFKDQRELLKYSIQDDPKR
FIFSNNEHGNCSMQIKHLKLSDSGEYHCLANNEYFHLKSSASWVLVMNSF
SDLIFDISIKQISQKTGDDVEMLCDPNNNNNNN

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **cellular component**
Term	Definition
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0030424	axon

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000418	head

Vocabulary: **INTERPRO**
Term	Definition
IPR036179	Ig-like_dom_sf
IPR003598	Ig_sub2
IPR003599	Ig_sub
IPR013783	Ig-like_fold
IPR007110	Ig-like_dom

Vocabulary: **molecular function**
Term	Definition
GO:0005515	protein binding

Vocabulary: **biological process**
Term	Definition
GO:0007411	axon guidance
GO:0035385	Roundabout signaling pathway

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR003598	Immunoglobulin subtype 2	SMART	SM00408	igc2_5	coord: 144..219 e-value: 5.1E-6 score: 36.0 coord: 46..115 e-value: 1.1 score: 6.6
IPR003599	Immunoglobulin subtype	SMART	SM00409	IG_3c	coord: 138..231 e-value: 3.7E-5 score: 33.1 coord: 40..123 e-value: 24.0 score: 8.1
IPR013783	Immunoglobulin-like fold	GENE3D	G3DSA:2.60.40.10		coord: 41..124 e-value: 6.4E-10 score: 41.1
IPR013783	Immunoglobulin-like fold	GENE3D	G3DSA:2.60.40.10		coord: 128..233 e-value: 9.5E-18 score: 66.3
None	No IPR available	PFAM	PF13927	Ig_3	coord: 46..112 e-value: 4.2E-9 score: 36.9 coord: 131..216 e-value: 2.3E-12 score: 47.3
None	No IPR available	PANTHER	PTHR45080	FAMILY NOT NAMED	coord: 49..218
None	No IPR available	PANTHER	PTHR45080:SF13	NEURAL CELL ADHESION MOLECULE L1	coord: 49..218
None	No IPR available	CDD	cd00096	Ig	coord: 51..119 e-value: 7.43683E-7 score: 43.7701
None	No IPR available	TMHMM	TMhelix		coord: 7..29
IPR007110	Immunoglobulin-like domain	PROSITE	PS50835	IG_LIKE	coord: 131..226 score: 11.406
IPR007110	Immunoglobulin-like domain	PROSITE	PS50835	IG_LIKE	coord: 50..119 score: 7.486
IPR036179	Immunoglobulin-like domain superfamily	SUPERFAMILY	SSF48726	Immunoglobulin	coord: 40..116
IPR036179	Immunoglobulin-like domain superfamily	SUPERFAMILY	SSF48726	Immunoglobulin	coord: 131..229

Main menu

Roundabout, axon guidance receptor, homolog 2 (Drosophila)

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 10

Owlery

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