Ring finger protein 34b

Overview
NameRing finger protein 34b
Smed IDSMED30019292
Length (bp)1137
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Ring finger protein 34b (SMED30019292) t-SNE clustered cells

Violin plots show distribution of expression levels for Ring finger protein 34b (SMED30019292) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Ring finger protein 34b (SMED30019292) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Ring finger protein 34b (SMED30019292) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30019292

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 8

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
intestinal phagocyteSMED30019292h1SMcG0002198 Contig4849GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30019292h1SMcG0011412 Contig4849GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
nervous systemSMED30019292h1SMcG0002198 dd_Smed_v4_1395_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30019292h1SMcG0002198 dd_Smed_v4_1395_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30019292h1SMcG0002198 dd_Smed_v4_1395_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30019292h1SMcG0002198 dd_Smed_v4_1395_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymaSMED30019292h1SMcG0002198 dd_Smed_v4_1395_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30019292h1SMcG0002198 dd_Smed_v4_1395_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Ring finger protein 34b vs. Ensembl Human
Match: RFFL (ring finger and FYVE like domain containing E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:24821])

HSP 1 Score: 65.0846 bits (157), Expect = 3.786e-11
Identity = 63/266 (23.68%), Postives = 115/266 (43.23%), Query Frame = 3 
Query:  237 CVFCDKEFCLSCTGK--ENTRICCKCNFVIATGIDKEVLKQFSIKQLRILTDNYNVPLKAINEKDQMIDAIL-----VSFKKSIKNNNQIVNVNE----LKQKMIDMGIKDSLD-KERKLEEEKIQSKKFSDYSNVGSEKNHXXXXXXXXXXXXXXXXXXXXXXXKEIKTFLDRFKVEYQDIIEKKELVSLAINLHQAFTQFKQQNGAYGNITPDKRHLECNICMDALINCVFLECCHSTCCYSCGSQMTFCPTCRGNIKQCLKIW 998
            C+ C K FC++C+ +     R+C  C    AT   +E L +  +K LR     +++  +   EK++++  +L     +S +   + +    +  E    L Q    M    S +      +   +   +  +       ++       +S S    L+DI  L+++++K  L R  V Y+   EK EL+     L++     +   GA  +   +     C ICMD+ I+CV LEC H   C  CG +M  CP CR  + + + ++
Sbjct:   63 CLDCKKNFCMTCSSQVGNGPRLCLLCQRFRATAFQREELMKMKVKDLRDYLSLHDISTEMCREKEELVLLVLGQQPVISQEDRTRASTLSPDFPEQQAFLTQPHSSMVPPTSPNLPSSSAQATSVPPAQVQENQQSIDSEDSFVPGRRASLSDLTDLEDIEGLTVRQLKEILARNFVNYKGCCEKWELMERVTRLYKDQKGLQHLGGAVPSGLEENL---CKICMDSPIDCVLLECGHMVTCTKCGKRMNECPICRQYVIRAVHVF 325
[Close]
BLAST of Ring finger protein 34b vs. Ensembl Human
Match: RNF34 (ring finger protein 34 [Source:HGNC Symbol;Acc:HGNC:17297])

HSP 1 Score: 62.3882 bits (150), Expect = 6.510e-11
Identity = 33/101 (32.67%), Postives = 53/101 (52.48%), Query Frame = 3 
Query:  696 KEIKTFLDRFKVEYQDIIEKKELVSLAINLHQAFTQFKQQNGAYGNITPDKRHLECNICMDALINCVFLECCHSTCCYSCGSQMTFCPTCRGNIKQCLKIW 998
            +++K  L R  V Y    EK ELV     L++   + ++  G    +  ++    C ICMDA+I+CV LEC H   C  CG +M+ CP CR  + + + ++
Sbjct:   78 RQLKEILARNFVNYSGCCEKWELVEKVNRLYKENEENQKSYGERLQLQDEEDDSLCRICMDAVIDCVLLECGHMVTCTKCGKRMSECPICRQYVVRAVHVF 178
[Close]
BLAST of Ring finger protein 34b vs. Ensembl Human
Match: RNF34 (ring finger protein 34 [Source:HGNC Symbol;Acc:HGNC:17297])

HSP 1 Score: 60.4622 bits (145), Expect = 1.713e-9
Identity = 33/101 (32.67%), Postives = 53/101 (52.48%), Query Frame = 3 
Query:  696 KEIKTFLDRFKVEYQDIIEKKELVSLAINLHQAFTQFKQQNGAYGNITPDKRHLECNICMDALINCVFLECCHSTCCYSCGSQMTFCPTCRGNIKQCLKIW 998
            +++K  L R  V Y    EK ELV     L++   + ++  G    +  ++    C ICMDA+I+CV LEC H   C  CG +M+ CP CR  + + + ++
Sbjct:  271 RQLKEILARNFVNYSGCCEKWELVEKVNRLYKENEENQKSYGERLQLQDEEDDSLCRICMDAVIDCVLLECGHMVTCTKCGKRMSECPICRQYVVRAVHVF 371
[Close]
BLAST of Ring finger protein 34b vs. Ensembl Human
Match: RNF34 (ring finger protein 34 [Source:HGNC Symbol;Acc:HGNC:17297])

HSP 1 Score: 60.4622 bits (145), Expect = 1.819e-9
Identity = 33/101 (32.67%), Postives = 53/101 (52.48%), Query Frame = 3 
Query:  696 KEIKTFLDRFKVEYQDIIEKKELVSLAINLHQAFTQFKQQNGAYGNITPDKRHLECNICMDALINCVFLECCHSTCCYSCGSQMTFCPTCRGNIKQCLKIW 998
            +++K  L R  V Y    EK ELV     L++   + ++  G    +  ++    C ICMDA+I+CV LEC H   C  CG +M+ CP CR  + + + ++
Sbjct:  270 RQLKEILARNFVNYSGCCEKWELVEKVNRLYKENEENQKSYGERLQLQDEEDDSLCRICMDAVIDCVLLECGHMVTCTKCGKRMSECPICRQYVVRAVHVF 370
[Close]
BLAST of Ring finger protein 34b vs. Ensembl Human
Match: RFFL (ring finger and FYVE like domain containing E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:24821])

HSP 1 Score: 56.6102 bits (135), Expect = 2.576e-9
Identity = 34/98 (34.69%), Postives = 47/98 (47.96%), Query Frame = 3 
Query:  696 KEIKTFLDRFKVEYQDIIEKKELVSLAINLHQ-------AFTQFKQQNGAYGNITPDKRHLECNICMDALINCVFLECCHSTCCYSCGSQMTFCPTCR 968
            +++K  L R  V Y+   EK EL+     L++         +  + QNG  G +        C ICMD+ I+CV LEC H   C  CG +M  CP CR
Sbjct:   45 RQLKEILARNFVNYKGCCEKWELMERVTRLYKDQKGLQHLVSGAEDQNG--GAVPSGLEENLCKICMDSPIDCVLLECGHMVTCTKCGKRMNECPICR 140
[Close]
BLAST of Ring finger protein 34b vs. Ensembl Fly
Match: CG17019 (gene:FBgn0033783 transcript:FBtr0087806)

HSP 1 Score: 56.225 bits (134), Expect = 2.936e-8
Identity = 35/101 (34.65%), Postives = 51/101 (50.50%), Query Frame = 3 
Query:  696 KEIKTFLDRFKVEYQDIIEKKELVSLAINLHQAFTQFKQQNGAYGNITPDKRHLECNICMDALINCVFLECCHSTCCYSCGSQMTFCPTCRGNIKQCLKIW 998
            K++K  L   +V+Y+   EK+EL+     L +   +      A   +  D+    C ICMDA I CVFLEC H   C SCG  +  CP CR  I + ++ +
Sbjct:  605 KQLKEVLMLHRVDYKGCCEKQELLDRVSRLWKTMRECP----AVEKLATDEL---CKICMDAPIECVFLECGHMATCTSCGKVLNECPICRQYIVRVVRFF 698
[Close]
BLAST of Ring finger protein 34b vs. Ensembl Fly
Match: CG17019 (gene:FBgn0033783 transcript:FBtr0339738)

HSP 1 Score: 56.225 bits (134), Expect = 2.936e-8
Identity = 35/101 (34.65%), Postives = 51/101 (50.50%), Query Frame = 3 
Query:  696 KEIKTFLDRFKVEYQDIIEKKELVSLAINLHQAFTQFKQQNGAYGNITPDKRHLECNICMDALINCVFLECCHSTCCYSCGSQMTFCPTCRGNIKQCLKIW 998
            K++K  L   +V+Y+   EK+EL+     L +   +      A   +  D+    C ICMDA I CVFLEC H   C SCG  +  CP CR  I + ++ +
Sbjct:  605 KQLKEVLMLHRVDYKGCCEKQELLDRVSRLWKTMRECP----AVEKLATDEL---CKICMDAPIECVFLECGHMATCTSCGKVLNECPICRQYIVRVVRFF 698
[Close]
BLAST of Ring finger protein 34b vs. Ensembl Fly
Match: dnr1 (gene:FBgn0260866 transcript:FBtr0071837)

HSP 1 Score: 50.8322 bits (120), Expect = 1.421e-6
Identity = 21/49 (42.86%), Postives = 29/49 (59.18%), Query Frame = 3 
Query:  855 LECNICMDALINCVFLECCHSTCCYSCGSQMTFCPTCRGNIKQCLKIWI 1001
            ++C ICMD  IN VF  CCH   C  C ++ + CP CR  I   +KI++
Sbjct:  546 MQCKICMDRAINTVFNPCCHVIACAQCAARCSNCPNCRVKITSVVKIYL 594
[Close]
BLAST of Ring finger protein 34b vs. Ensembl Fly
Match: dnr1 (gene:FBgn0260866 transcript:FBtr0330229)

HSP 1 Score: 50.447 bits (119), Expect = 1.851e-6
Identity = 21/49 (42.86%), Postives = 29/49 (59.18%), Query Frame = 3 
Query:  855 LECNICMDALINCVFLECCHSTCCYSCGSQMTFCPTCRGNIKQCLKIWI 1001
            ++C ICMD  IN VF  CCH   C  C ++ + CP CR  I   +KI++
Sbjct:  546 MQCKICMDRAINTVFNPCCHVIACAQCAARCSNCPNCRVKITSVVKIYL 594
[Close]
BLAST of Ring finger protein 34b vs. Ensembl Zebrafish
Match: rffl (ring finger and FYVE-like domain containing E3 ubiquitin protein ligase [Source:ZFIN;Acc:ZDB-GENE-040426-2274])

HSP 1 Score: 69.3218 bits (168), Expect = 9.047e-13
Identity = 63/268 (23.51%), Postives = 115/268 (42.91%), Query Frame = 3 
Query:  237 CVFCDKEFCLSCTGKENTR--ICCKCNFVIATGIDKEVLKQFSIKQLRILTDNYNVPLKAINEKDQMIDAILVSFKKSIKNNNQIVNVNEL-KQKMIDMGI------KDSLDKERKLEEEKIQSKKFSDYSNVGSEKNHXXXXXXXXXXXXXXXXXXXXXXXKEIKTFLDRFKVEYQDIIEKKELVSLAINLH--QAFTQFKQQNGAYGNITPDKRHLE---CNICMDALINCVFLECCHSTCCYSCGSQMTFCPTCRGNIKQCLKIW 998
            C+ C K +C  C+ ++  +  +C  C       +++  L +  +K LR     + VP +   EK+++++ +L     +   +        L +Q+ +D  +       ++   E   + + + + +FSD   V +     S+    S      L        +++K  L R  V+Y+   EK EL+     L+  Q   Q    N   G  T     +E   C ICMD+ I+CV LEC H   C  CG +M+ CP CR  + + + ++
Sbjct:   62 CMDCKKSYCSQCSTQQELQPWLCRTCQRFRGILLERAELMKLKVKDLRDYLHLHGVPTQMCREKEELVELVLGQQTPTSDTHIPAPETTRLDQQETLDTPVITVSPSGNNNTTELGPQTQAMDNGQFSDSEEVLAPGRRASLSDLGSVEDIEDLSV------RQLKEILARNFVDYKGCCEKWELMERVTRLYNDQKDLQNMVSNATEGTDTGSGTAVEENLCKICMDSPIDCVLLECGHMVTCTKCGKRMSECPICRQYVVRAVHVF 323
[Close]
BLAST of Ring finger protein 34b vs. Ensembl Zebrafish
Match: rffl (ring finger and FYVE-like domain containing E3 ubiquitin protein ligase [Source:ZFIN;Acc:ZDB-GENE-040426-2274])

HSP 1 Score: 67.0106 bits (162), Expect = 7.690e-12
Identity = 68/294 (23.13%), Postives = 121/294 (41.16%), Query Frame = 3 
Query:  237 CVFCDKEFCLSCTGKENTR--ICCKCNFVIATGIDKEVLKQFSIKQLRILTDNYNVPLKAINEKDQMIDAIL----------VSFKKSIKNNNQIV--------------NVNELK---------QKMIDMGIKDSLDKERKLEEEKIQSKKFSDYSNVGSEKNHXXXXXXXXXXXXXXXXXXXXXXXKEIKTFLDRFKVEYQDIIEKKELVSLAINLH--QAFTQFKQQNGAYGNITPDKRHLE---CNICMDALINCVFLECCHSTCCYSCGSQMTFCPTCRGNIKQCLKIW 998
            C+ C K +C  C+ ++  +  +C  C       +++  L +  +K LR     + VP +   EK+++++ +L          +   ++ + + Q                N  EL          Q + ++  +  +D E ++E+E+     FSD   V +     S+    S      L        +++K  L R  V+Y+   EK EL+     L+  Q   Q    N   G  T     +E   C ICMD+ I+CV LEC H   C  CG +M+ CP CR  + + + ++
Sbjct:   62 CMDCKKSYCSQCSTQQELQPWLCRTCQRFRGILLERAELMKLKVKDLRDYLHLHGVPTQMCREKEELVELVLGQQTPTSDTHIPAPETTRLDQQETLDTPVITVSPSGNNNTTELGPQTQAMDNGQSLAEVTAESEMDTELQMEQEQ-----FSDSEEVLAPGRRASLSDLGSVEDIEDLSV------RQLKEILARNFVDYKGCCEKWELMERVTRLYNDQKDLQNMVSNATEGTDTGSGTAVEENLCKICMDSPIDCVLLECGHMVTCTKCGKRMSECPICRQYVVRAVHVF 344
[Close]
BLAST of Ring finger protein 34b vs. Ensembl Zebrafish
Match: rnf34a (ring finger protein 34a [Source:ZFIN;Acc:ZDB-GENE-030131-6135])

HSP 1 Score: 61.2326 bits (147), Expect = 6.173e-10
Identity = 74/300 (24.67%), Postives = 121/300 (40.33%), Query Frame = 3 
Query:  192 CDICKN-ISRERKLIQCVFCDKEFCLSCTG-KENTRICCKCNFVIATGIDKEVLKQFSIKQLRILTDNYNVPLKAINEKDQMIDAILVSFKKSIKNNNQIVNVNELKQKMIDMGIKDSLDKERKLEE--EKIQSKKFSDYSNVGSEKN-------------------HXXXXXXXXXXXXXXXXXXXXXXXKEIKTFLDRFKVEYQDIIEKKELVSLAINLHQAFTQFKQQNGAYGN-ITPDKRHLE-------CNICMDALINCVFLECCHSTCCYSCGSQMTFCPTCRGNIKQCLKIW 998
            C  C+   S  R+   C  C K FC  C+  +EN R C  C+ +  T   +  L +  +K LR      N+      EK+ ++D +L       +++    ++           I++       L    E I     S+ +N   E +                          +S S   SLDD+ +L+++++K  L R  V +    EK ELV     L++     ++      N IT D    +       C ICMDA+I+CV LEC H   C  CG +M+ CP CR  + + + ++
Sbjct:   62 CQACRQAFSVFRRRYICCDCTKSFCSLCSVLQENLRRCTTCHLLKGTAFQRSQLMRLRVKDLRQYLMLRNINTDTCREKEDLVDLVLCHHGAESEDDPDTPSLQSHPLYSPPPLIEEPTSPLSALSPTREPISRSNSSESTNQDIEDSTSVSLLNLDQTEHTPEVSPQTRRRARASLSDLSSLDDVEQLTVRQLKEILARNFVSFSGCCEKWELVERVRRLYRENEDNRKSMENVSNPITADSCRTQLSNDDNLCRICMDAVIDCVLLECGHMVTCTKCGKRMSECPICRQYVIRAVHVF 361
[Close]
BLAST of Ring finger protein 34b vs. Ensembl Zebrafish
Match: zgc:171740 (zgc:171740 [Source:ZFIN;Acc:ZDB-GENE-071004-29])

HSP 1 Score: 54.6842 bits (130), Expect = 4.949e-8
Identity = 33/108 (30.56%), Postives = 51/108 (47.22%), Query Frame = 3 
Query:  696 KEIKTFLDRFKVEYQDIIEKKELVSLAI-------NLHQAFTQFKQQNGAYGNITPDKRHLECNICMDALINCVFLECCHSTCCYSCGSQMTFCPTCRGNIKQCLKIW 998
            +++K  L R  V YQ   EK EL+           +LH   +    +       +  + +L C ICMD+ I+CV LEC H   C  CG +M  CP CR  + + + ++
Sbjct:  163 RQLKEILARNFVNYQGCCEKWELMEKVTHLFNDQKDLHNLVSNTNTEAADPAEPSGQEENL-CKICMDSPIDCVLLECGHMVTCSKCGKRMNECPICRQYVVRAVHVF 269
[Close]
BLAST of Ring finger protein 34b vs. Ensembl Zebrafish
Match: zgc:171740 (zgc:171740 [Source:ZFIN;Acc:ZDB-GENE-071004-29])

HSP 1 Score: 54.6842 bits (130), Expect = 4.949e-8
Identity = 33/108 (30.56%), Postives = 51/108 (47.22%), Query Frame = 3 
Query:  696 KEIKTFLDRFKVEYQDIIEKKELVSLAI-------NLHQAFTQFKQQNGAYGNITPDKRHLECNICMDALINCVFLECCHSTCCYSCGSQMTFCPTCRGNIKQCLKIW 998
            +++K  L R  V YQ   EK EL+           +LH   +    +       +  + +L C ICMD+ I+CV LEC H   C  CG +M  CP CR  + + + ++
Sbjct:  163 RQLKEILARNFVNYQGCCEKWELMEKVTHLFNDQKDLHNLVSNTNTEAADPAEPSGQEENL-CKICMDSPIDCVLLECGHMVTCSKCGKRMNECPICRQYVVRAVHVF 269
[Close]
BLAST of Ring finger protein 34b vs. Ensembl Xenopus
Match: dctn2 (dynactin subunit 2 [Source:Xenbase;Acc:XB-GENE-1000632])

HSP 1 Score: 64.3142 bits (155), Expect = 6.300e-11
Identity = 61/271 (22.51%), Postives = 110/271 (40.59%), Query Frame = 3 
Query:  237 CVFCDKEFCLSCTGKENT--RICCKCNFVIATGIDKEVLKQFSIKQLRILTDNYNVPLKAINEKDQMIDAILVSFKKSIKNNNQIVNVNELKQKMIDMGIKDSLDKERKLEEEKIQSKKFSDYSNVGSEKNHXXXXXXXXXXXXXXXXXXX------------XXXXKEIKTFLDRFKVEYQDIIEKKELVSLAINLHQAFTQFKQQNGAYG---NITPDKRHLECNICMDALINCVFLECCHSTCCYSCGSQMTFCPTCRGNIKQCLKIW 998
            C+ C   +C +C  + N    +C  C  + +T  D++ L +  +K LR      ++P+    EK+ ++  IL         +   V      Q   +     S             ++  S  +  G+   HL    SS    +++                  LS++++K  L R  V+Y+   EK EL+     L+      ++   A     N T  + ++ C +CMD+ I+CV LEC H   C  CG +M+ CP CR  + + + ++
Sbjct:   59 CMDCKNYYCAACLIQTNNGHSLCQVCRSIRSTAFDRDELMKLRVKDLRDYLTLKDIPIDLCREKEDLVQLILFHKPPVFSADGTNVPTASSNQSTTNQRTDSSYTPGHPPYNTSAANRTGSSNAQ-GTAGEHLVDSESSDPEENLAPGRRASLSDLTCVDDIEALSVRQLKEILARNFVDYKGCCEKWELMERVTRLYNEQKGLQEMAAAEAEGINGTTSEENI-CKVCMDSPIDCVLLECGHMVTCTKCGKRMSECPICRQYVVRAVHVF 327
[Close]
BLAST of Ring finger protein 34b vs. Ensembl Xenopus
Match: dctn2 (dynactin subunit 2 [Source:Xenbase;Acc:XB-GENE-1000632])

HSP 1 Score: 63.5438 bits (153), Expect = 1.163e-10
Identity = 61/268 (22.76%), Postives = 108/268 (40.30%), Query Frame = 3 
Query:  237 CVFCDKEFCLSCTGKENT--RICCKCNFVIATGIDKEVLKQFSIKQLRILTDNYNVPLKAINEKDQMIDAILVSFKKSIKNNNQIVNVNELKQKMIDMGIKDSLDKERKLEEEKIQSKKFSDYSNVGSEKNHXXXXXXXXXXXXXXXXXXX------------XXXXKEIKTFLDRFKVEYQDIIEKKELVSLAINLHQAFTQFKQQNGAYGNITPDKRHLECNICMDALINCVFLECCHSTCCYSCGSQMTFCPTCRGNIKQCLKIW 998
            C+ C   +C +C  + N    +C  C  + +T  D++ L +  +K LR      ++P+    EK+ ++  IL         +   V      Q   +     S             ++  S  +  G+   HL    SS    +++                  LS++++K  L R  V+Y+   EK EL+     L+       Q+ G  G  + +     C +CMD+ I+CV LEC H   C  CG +M+ CP CR  + + + ++
Sbjct:   59 CMDCKNYYCAACLIQTNNGHSLCQVCRSIRSTAFDRDELMKLRVKDLRDYLTLKDIPIDLCREKEDLVQLILFHKPPVFSADGTNVPTASSNQSTTNQRTDSSYTPGHPPYNTSAANRTGSSNAQ-GTAGEHLVDSESSDPEENLAPGRRASLSDLTCVDDIEALSVRQLKEILARNFVDYKGCCEKWELMERVTRLYNEQKGL-QEMGINGTTSEENI---CKVCMDSPIDCVLLECGHMVTCTKCGKRMSECPICRQYVVRAVHVF 321
[Close]
BLAST of Ring finger protein 34b vs. Ensembl Xenopus
Match: prlr (prolactin receptor [Source:Xenbase;Acc:XB-GENE-494789])

HSP 1 Score: 55.8398 bits (133), Expect = 4.311e-8
Identity = 36/110 (32.73%), Postives = 55/110 (50.00%), Query Frame = 3 
Query:  696 KEIKTFLDRFKVEYQDIIEKKELVSLAINLHQAFTQFKQQ-NGAYGNITPDK--RHLE------CNICMDALINCVFLECCHSTCCYSCGSQMTFCPTCRGNIKQCLKIW 998
            +++K  L R  V Y    EK ELV     L++   + ++    +     P+K  R L       C ICMDA+I+CV LEC H   C  CG +M+ CP CR  + + + ++
Sbjct:  251 RQLKEILARNFVNYSGCCEKWELVEKVSRLYRENEENRKSLQKSESKADPEKECRSLTGSDDNLCRICMDAVIDCVLLECGHMVTCTKCGKRMSECPICRQYVVRAVHVF 360
[Close]
BLAST of Ring finger protein 34b vs. Ensembl Xenopus
Match: prlr (prolactin receptor [Source:Xenbase;Acc:XB-GENE-494789])

HSP 1 Score: 55.8398 bits (133), Expect = 4.628e-8
Identity = 35/110 (31.82%), Postives = 56/110 (50.91%), Query Frame = 3 
Query:  696 KEIKTFLDRFKVEYQDIIEKKELVSLAINLHQAFTQFK---QQNGAYGNITPDKRHLE------CNICMDALINCVFLECCHSTCCYSCGSQMTFCPTCRGNIKQCLKIW 998
            +++K  L R  V Y    EK ELV     L++   + +   Q++ +  +   + R L       C ICMDA+I+CV LEC H   C  CG +M+ CP CR  + + + ++
Sbjct:  248 RQLKEILARNFVNYSGCCEKWELVEKVSRLYRENEENRKSLQKSESKADPEKECRSLTGSDDNLCRICMDAVIDCVLLECGHMVTCTKCGKRMSECPICRQYVVRAVHVF 357
[Close]
BLAST of Ring finger protein 34b vs. Ensembl Xenopus
Match: prlr (prolactin receptor [Source:Xenbase;Acc:XB-GENE-494789])

HSP 1 Score: 55.8398 bits (133), Expect = 5.055e-8
Identity = 35/110 (31.82%), Postives = 56/110 (50.91%), Query Frame = 3 
Query:  696 KEIKTFLDRFKVEYQDIIEKKELVSLAINLHQAFTQFK---QQNGAYGNITPDKRHLE------CNICMDALINCVFLECCHSTCCYSCGSQMTFCPTCRGNIKQCLKIW 998
            +++K  L R  V Y    EK ELV     L++   + +   Q++ +  +   + R L       C ICMDA+I+CV LEC H   C  CG +M+ CP CR  + + + ++
Sbjct:  256 RQLKEILARNFVNYSGCCEKWELVEKVSRLYRENEENRKSLQKSESKADPEKECRSLTGSDDNLCRICMDAVIDCVLLECGHMVTCTKCGKRMSECPICRQYVVRAVHVF 365
[Close]
BLAST of Ring finger protein 34b vs. Ensembl Mouse
Match: Rffl (ring finger and FYVE like domain containing protein [Source:MGI Symbol;Acc:MGI:1914588])

HSP 1 Score: 65.855 bits (159), Expect = 1.927e-11
Identity = 70/283 (24.73%), Postives = 122/283 (43.11%), Query Frame = 3 
Query:  237 CVFCDKEFCLSCTGKEN--TRICCKCNFVIATGIDKEVLKQFSIKQLRILTDNYNVPLKAINEKDQMIDAILVSFKKSIKNNNQIVNVNELKQKMIDM-----------------GIKDSLDKERKL---EEEKIQSKKFSDYSNVGSEKNHXXXXXXXXXXXXXXXXXXXXXXXKEIKTFLDRFKVEYQDIIEKKELVSLAINLHQAFTQFKQ-------QNGAYGNITPDKRHLECNICMDALINCVFLECCHSTCCYSCGSQMTFCPTCRGNIKQCLKIW 998
            C+ C K FC++C+ +E    R+C  C    AT   +E L +  +K LR     +++  +   EK++++   LV  ++ + +      V  L Q   +                  G+  S  +   +   ++++ Q    S+ S V   +        +S S    L+DI  L+++++K  L R  V Y+   EK EL+     L++     +        QNG  G +        C ICMD+ I+CV LEC H   C  CG +M  CP CR  + + + ++
Sbjct:   63 CLDCKKNFCMTCSSQEGNGPRLCLLCLRFRATAFQREELMKMKVKDLRDYLSLHDISTEMCREKEELV--FLVLGQQPVISEADRTRVPHLPQAFPEQQAFLTQPQTSTVPPTSPGLPSSPAQVTSVPLAQDQETQQSVDSEDSFVPGRR--------ASLSDLTHLEDIEGLTVRQLKEILARNFVNYKGCCEKWELMERVTRLYKDQKGLQHLVSGNEDQNG--GAVPSGLEENLCKICMDSPIDCVLLECGHMVTCTKCGKRMNECPICRQYVIRAVHVF 333
[Close]
BLAST of Ring finger protein 34b vs. Ensembl Mouse
Match: Rnf34 (ring finger protein 34 [Source:MGI Symbol;Acc:MGI:2153340])

HSP 1 Score: 60.077 bits (144), Expect = 1.515e-9
Identity = 33/101 (32.67%), Postives = 53/101 (52.48%), Query Frame = 3 
Query:  696 KEIKTFLDRFKVEYQDIIEKKELVSLAINLHQAFTQFKQQNGAYGNITPDKRHLECNICMDALINCVFLECCHSTCCYSCGSQMTFCPTCRGNIKQCLKIW 998
            +++K  L R  V Y    EK ELV     L++   + ++  G    +  ++    C ICMDA+I+CV LEC H   C  CG +M+ CP CR  + + + ++
Sbjct:  274 RQLKEILARNFVNYSGCCEKWELVEKVNRLYKENEENQKSYGERMQLQDEEDDSLCRICMDAVIDCVLLECGHMVTCTKCGKRMSECPICRQYVVRAVHVF 374
[Close]
BLAST of Ring finger protein 34b vs. Ensembl Mouse
Match: Rffl (ring finger and FYVE like domain containing protein [Source:MGI Symbol;Acc:MGI:1914588])

HSP 1 Score: 54.299 bits (129), Expect = 1.211e-7
Identity = 34/108 (31.48%), Postives = 51/108 (47.22%), Query Frame = 3 
Query:  696 KEIKTFLDRFKVEYQDIIEKKELVSLAINLHQAFTQFKQ-------QNGAYGNITPDKRHLECNICMDALINCVFLECCHSTCCYSCGSQMTFCPTCRGNIKQCLKIW 998
            +++K  L R  V Y+   EK EL+     L++     +        QNG  G +        C ICMD+ I+CV LEC H   C  CG +M  CP CR  + + + ++
Sbjct:  256 RQLKEILARNFVNYKGCCEKWELMERVTRLYKDQKGLQHLVSGNEDQNG--GAVPSGLEENLCKICMDSPIDCVLLECGHMVTCTKCGKRMNECPICRQYVIRAVHVF 361
[Close]
BLAST of Ring finger protein 34b vs. Ensembl Mouse
Match: Rffl (ring finger and FYVE like domain containing protein [Source:MGI Symbol;Acc:MGI:1914588])

HSP 1 Score: 54.299 bits (129), Expect = 1.211e-7
Identity = 34/108 (31.48%), Postives = 51/108 (47.22%), Query Frame = 3 
Query:  696 KEIKTFLDRFKVEYQDIIEKKELVSLAINLHQAFTQFKQ-------QNGAYGNITPDKRHLECNICMDALINCVFLECCHSTCCYSCGSQMTFCPTCRGNIKQCLKIW 998
            +++K  L R  V Y+   EK EL+     L++     +        QNG  G +        C ICMD+ I+CV LEC H   C  CG +M  CP CR  + + + ++
Sbjct:  256 RQLKEILARNFVNYKGCCEKWELMERVTRLYKDQKGLQHLVSGNEDQNG--GAVPSGLEENLCKICMDSPIDCVLLECGHMVTCTKCGKRMNECPICRQYVIRAVHVF 361
[Close]
BLAST of Ring finger protein 34b vs. Ensembl Mouse
Match: Rffl (ring finger and FYVE like domain containing protein [Source:MGI Symbol;Acc:MGI:1914588])

HSP 1 Score: 54.299 bits (129), Expect = 1.258e-7
Identity = 34/108 (31.48%), Postives = 51/108 (47.22%), Query Frame = 3 
Query:  696 KEIKTFLDRFKVEYQDIIEKKELVSLAINLHQAFTQFKQ-------QNGAYGNITPDKRHLECNICMDALINCVFLECCHSTCCYSCGSQMTFCPTCRGNIKQCLKIW 998
            +++K  L R  V Y+   EK EL+     L++     +        QNG  G +        C ICMD+ I+CV LEC H   C  CG +M  CP CR  + + + ++
Sbjct:  291 RQLKEILARNFVNYKGCCEKWELMERVTRLYKDQKGLQHLVSGNEDQNG--GAVPSGLEENLCKICMDSPIDCVLLECGHMVTCTKCGKRMNECPICRQYVIRAVHVF 396
[Close]
BLAST of Ring finger protein 34b vs. UniProt/SwissProt
Match: sp|Q969K3|RNF34_HUMAN (E3 ubiquitin-protein ligase RNF34 OS=Homo sapiens OX=9606 GN=RNF34 PE=1 SV=1)

HSP 1 Score: 60.4622 bits (145), Expect = 7.294e-9
Identity = 33/101 (32.67%), Postives = 53/101 (52.48%), Query Frame = 3 
Query:  696 KEIKTFLDRFKVEYQDIIEKKELVSLAINLHQAFTQFKQQNGAYGNITPDKRHLECNICMDALINCVFLECCHSTCCYSCGSQMTFCPTCRGNIKQCLKIW 998
            +++K  L R  V Y    EK ELV     L++   + ++  G    +  ++    C ICMDA+I+CV LEC H   C  CG +M+ CP CR  + + + ++
Sbjct:  270 RQLKEILARNFVNYSGCCEKWELVEKVNRLYKENEENQKSYGERLQLQDEEDDSLCRICMDAVIDCVLLECGHMVTCTKCGKRMSECPICRQYVVRAVHVF 370
[Close]
BLAST of Ring finger protein 34b vs. UniProt/SwissProt
Match: sp|Q5NVC7|RNF34_PONAB (E3 ubiquitin-protein ligase RNF34 OS=Pongo abelii OX=9601 GN=RNF34 PE=2 SV=2)

HSP 1 Score: 60.4622 bits (145), Expect = 7.562e-9
Identity = 33/101 (32.67%), Postives = 53/101 (52.48%), Query Frame = 3 
Query:  696 KEIKTFLDRFKVEYQDIIEKKELVSLAINLHQAFTQFKQQNGAYGNITPDKRHLECNICMDALINCVFLECCHSTCCYSCGSQMTFCPTCRGNIKQCLKIW 998
            +++K  L R  V Y    EK ELV     L++   + ++  G    +  ++    C ICMDA+I+CV LEC H   C  CG +M+ CP CR  + + + ++
Sbjct:  270 RQLKEILARNFVNYSGCCEKWELVEKVNRLYKENEENQKSYGERLQLQDEEDDSLCRICMDAVIDCVLLECGHMVTCTKCGKRMSECPICRQYVVRAVHVF 370
[Close]
BLAST of Ring finger protein 34b vs. UniProt/SwissProt
Match: sp|Q5E9J6|RNF34_BOVIN (E3 ubiquitin-protein ligase RNF34 OS=Bos taurus OX=9913 GN=RNF34 PE=2 SV=1)

HSP 1 Score: 60.4622 bits (145), Expect = 7.921e-9
Identity = 33/101 (32.67%), Postives = 53/101 (52.48%), Query Frame = 3 
Query:  696 KEIKTFLDRFKVEYQDIIEKKELVSLAINLHQAFTQFKQQNGAYGNITPDKRHLECNICMDALINCVFLECCHSTCCYSCGSQMTFCPTCRGNIKQCLKIW 998
            +++K  L R  V Y    EK ELV     L++   + ++  G    +  ++    C ICMDA+I+CV LEC H   C  CG +M+ CP CR  + + + ++
Sbjct:  273 RQLKEILARNFVNYSGCCEKWELVEKVNRLYKENEENQKSYGERLQLQDEEDDSLCRICMDAVIDCVLLECGHMVTCTKCGKRMSECPICRQYVVRAVHVF 373
[Close]
BLAST of Ring finger protein 34b vs. UniProt/SwissProt
Match: sp|Q99KR6|RNF34_MOUSE (E3 ubiquitin-protein ligase RNF34 OS=Mus musculus OX=10090 GN=Rnf34 PE=1 SV=1)

HSP 1 Score: 60.4622 bits (145), Expect = 8.541e-9
Identity = 33/101 (32.67%), Postives = 53/101 (52.48%), Query Frame = 3 
Query:  696 KEIKTFLDRFKVEYQDIIEKKELVSLAINLHQAFTQFKQQNGAYGNITPDKRHLECNICMDALINCVFLECCHSTCCYSCGSQMTFCPTCRGNIKQCLKIW 998
            +++K  L R  V Y    EK ELV     L++   + ++  G    +  ++    C ICMDA+I+CV LEC H   C  CG +M+ CP CR  + + + ++
Sbjct:  274 RQLKEILARNFVNYSGCCEKWELVEKVNRLYKENEENQKSYGERMQLQDEEDDSLCRICMDAVIDCVLLECGHMVTCTKCGKRMSECPICRQYVVRAVHVF 374
[Close]
BLAST of Ring finger protein 34b vs. UniProt/SwissProt
Match: sp|Q6AYH3|RNF34_RAT (E3 ubiquitin-protein ligase RNF34 OS=Rattus norvegicus OX=10116 GN=Rnf34 PE=1 SV=1)

HSP 1 Score: 60.4622 bits (145), Expect = 9.083e-9
Identity = 33/101 (32.67%), Postives = 53/101 (52.48%), Query Frame = 3 
Query:  696 KEIKTFLDRFKVEYQDIIEKKELVSLAINLHQAFTQFKQQNGAYGNITPDKRHLECNICMDALINCVFLECCHSTCCYSCGSQMTFCPTCRGNIKQCLKIW 998
            +++K  L R  V Y    EK ELV     L++   + ++  G    +  ++    C ICMDA+I+CV LEC H   C  CG +M+ CP CR  + + + ++
Sbjct:  279 RQLKEILARNFVNYSGCCEKWELVEKVNRLYKENEENQKSYGERMQLQDEEDDSLCRICMDAVIDCVLLECGHMVTCTKCGKRMSECPICRQYVVRAVHVF 379
[Close]
BLAST of Ring finger protein 34b vs. TrEMBL
Match: A0A3P8Z661 (Ring finger protein 34a OS=Esox lucius OX=8010 PE=4 SV=1)

HSP 1 Score: 88.1965 bits (217), Expect = 1.419e-15
Identity = 68/267 (25.47%), Postives = 116/267 (43.45%), Query Frame = 3 
Query:  237 CVFCDKEFCLSCTG-KENTRICCKCNFVIATGIDKEVLKQFSIKQLRILTDNYNVPLKAINEKDQMIDAILV-SFKKSIKNNNQIVNVNELKQKMIDMGIKDSLDKERKLEEEKIQSKKFSDYSNVG----SEKNHXXXXXXXXXXXXXXXXXXXXX-------XXKEIKTFLDRFKVEYQDIIEKKELVSLAINLHQAFTQFKQQNGAYGNITPDKRHLECNICMDALINCVFLECCHSTCCYSCGSQMTFCPTCRGNIKQCLKIW 998
            C  C K FC+ CT  +EN RIC  C+ +  T   +  L +  +K LR      NVP     EK+ ++D +L     +  +++    ++N     +  + +  S  +   L    +  +   D +++        +H       +     +              S++++K  L R  V Y    EK ELV     L++   Q ++  G  G +T    +L C ICMDA+I+CV LEC H   C  CG +M+ CP CR  + + + ++
Sbjct:  108 CCDCKKSFCMLCTVLQENLRICATCHLLKGTAFQRPQLMRLRVKDLRQYLLLRNVPTDTCREKEDLVDLVLCHQGAEGDEDDPDTASLNSHPLYIPPISVARSASELSALSVFVLSVQDVGDTTSLSLLNLEPSDHTPEVSPQTRQRARASLSDISSLRDIEDLSVRQLKEILARNFVNYSGCCEKWELVERVSRLYRETEQNRKSYGEKGQLTNLDENL-CRICMDAVIDCVLLECGHMVTCTKCGKRMSECPICRQYVVRAVHVF 373
[Close]
BLAST of Ring finger protein 34b vs. TrEMBL
Match: A0A3Q4G4I9 (Ring finger protein 34b OS=Neolamprologus brichardi OX=32507 PE=4 SV=1)

HSP 1 Score: 87.4261 bits (215), Expect = 1.810e-15
Identity = 74/284 (26.06%), Postives = 122/284 (42.96%), Query Frame = 3 
Query:  192 CDICKNISRERKLIQCVFCDKEFCLSCTG-KENTRICCKCNFVIATGIDKEVLKQFSIKQLRILTDNYNVPLKAINEKDQMIDAILVSFKKSIKNNNQIVNVNELKQKMIDMGIKDSLDKERKLEEEKIQSKKFSDY----------SNVGSEKNHXXXXXXXXXXXXXX----XXXXXXXXXKEIKTFLDRFKVEYQDIIEKKELVSLAINLHQAFTQFKQQNGAYGNITPDKRHLECNICMDALINCVFLECCHSTCCYSCGSQMTFCPTCRGNIKQCLKIW 998
            C +  ++ R + +  C  C K FC  C+  +EN R C  C+ +  T   +  L Q  +K LR      N+P     EK+ ++D +L    +  +  +   +++ L                R   E+ + S    D           S V S + H+S          +S     + I  LS++++K  L R  V Y    EK EL+     L++   Q ++ NG    +  D+    C ICMDA+I+CV LEC H   C  CG +M+ CP CR  + + + ++
Sbjct:   58 CGLAFSVFRRKHI--CCDCKKSFCALCSVLQENLRCCTTCHLLRGTAFQRPRLMQLRVKDLRQYLLLRNIPTDTCREKEDLVDLVLCHQGEEDEGGDDTDSLHSLPHSRA----ASPPSATRSTSEQSVLSASQGDVLSPSDSSGTTSQVSSWQPHVSPATQRRIRASLSDLDNEEAIENLSVRQLKEILARNFVNYSGCCEKWELLERVHRLYRENEQNRKSNGVKAQLAADEN--LCRICMDAIIDCVLLECGHMVTCTKCGKRMSECPICRQYVVRAVHVF 333
[Close]
BLAST of Ring finger protein 34b vs. TrEMBL
Match: A0A3P8STA5 (Ring finger protein 34a OS=Amphiprion percula OX=161767 PE=4 SV=1)

HSP 1 Score: 86.2705 bits (212), Expect = 4.290e-15
Identity = 76/272 (27.94%), Postives = 118/272 (43.38%), Query Frame = 3 
Query:  222 RKLIQCVFCDKEFCLSCTG-KENTRICCKCNFVIATGIDKEVLKQFSIKQLRILTDNYNVPLKAINEKDQMIDAILVSFKKSIKNNNQIVNVNELKQKMIDMGIKDSLDKERKLEEEKIQSKKFSDYSNVGSEKNHXXXXXXXXXXXXXXXXXXXXXXXKEIKTFLDRFKVEYQDIIEKKELVSLAINLHQAFTQFKQQNG----------AYGNITPDKRHLE--CNICMDALINCVFLECCHSTCCYSCGSQMTFCPTCRGNIKQCLKIW 998
            RK I C  C K FC  C+  +EN RIC  C+ + AT   +  L +  +K LR     +N+P     EK+ ++D +L       + +    +++             S  +       + +    SD S+             +S S   SL DI  LS++++K  L R  V Y    EK ELV     L++   + ++  G          +YG   P   H +  C ICMDA+I+CV LEC H   C  CG +M  CP CR  + + + ++
Sbjct:   72 RKYI-CYDCKKSFCSLCSVLQENLRICATCHLLKATAFQRPRLMRLRVKDLRQYLMLHNIPTDTCREKEDLVDLVLCHQGIEEEEDGDTASLHSRSLYTPTPSTTQSASELSAFAASQEEPLSRSDSSDTNQVSPQTRRRARASLSDISSLRDIEGLSVRQLKEILARNFVNYSGCCEKWELVERVSRLYRETEENRKSCGYSFCHDGNECSYGENCPLTIHDDNLCRICMDAVIDCVLLECGHMVTCTKCGKRMNECPICRQYVVRAVHVF 342
[Close]
BLAST of Ring finger protein 34b vs. TrEMBL
Match: A0A3Q1AJS2 (Ring finger protein 34a OS=Amphiprion ocellaris OX=80972 PE=4 SV=1)

HSP 1 Score: 85.8853 bits (211), Expect = 5.714e-15
Identity = 76/272 (27.94%), Postives = 118/272 (43.38%), Query Frame = 3 
Query:  222 RKLIQCVFCDKEFCLSCTG-KENTRICCKCNFVIATGIDKEVLKQFSIKQLRILTDNYNVPLKAINEKDQMIDAILVSFKKSIKNNNQIVNVNELKQKMIDMGIKDSLDKERKLEEEKIQSKKFSDYSNVGSEKNHXXXXXXXXXXXXXXXXXXXXXXXKEIKTFLDRFKVEYQDIIEKKELVSLAINLHQAFTQFKQQNG----------AYGNITPDKRHLE--CNICMDALINCVFLECCHSTCCYSCGSQMTFCPTCRGNIKQCLKIW 998
            RK I C  C K FC  C+  +EN RIC  C+ + AT   +  L +  +K LR     +N+P     EK+ ++D +L       + +    +++             S  +       + +    SD S+             +S S   SL DI  LS++++K  L R  V Y    EK ELV     L++   + ++  G          +YG   P   H +  C ICMDA+I+CV LEC H   C  CG +M  CP CR  + + + ++
Sbjct:   72 RKYI-CCDCKKSFCSLCSVLQENLRICATCHLLKATAFQRPRLMRLRVKDLRQYLMLHNIPTDTCREKEDLVDLVLCHQGIEEEEDGDTASLHSRSLYTPTPSTTQSASELSAFAASQEEPLSRSDSSDTNQVSPQTRRRARASLSDISSLRDIEGLSVRQLKEILARNFVNYSGCCEKWELVERVSRLYRETEENRKSCGYSFCHDGNECSYGENCPLTIHDDNLCRICMDAVIDCVLLECGHMVTCTKCGKRMNECPICRQYVVRAVHVF 342
[Close]
BLAST of Ring finger protein 34b vs. TrEMBL
Match: A0A3P9LQJ7 (Ring finger protein 34a OS=Oryzias latipes OX=8090 PE=4 SV=1)

HSP 1 Score: 85.1149 bits (209), Expect = 1.021e-14
Identity = 75/278 (26.98%), Postives = 117/278 (42.09%), Query Frame = 3 
Query:  237 CVFCDKEFC-LSCTGKENTRICCKCNFVIATGIDKEVLKQFSIKQLRILTDNYNVPLKAINEKDQMIDAIL--------------VSFKKSIKNNNQIVNVNELKQKMIDMGIKDS-----LDKERKLEEEKIQSKKFS--DYSNVGSEKNHXXXXXXXXXXXXXXXXXXXXXXXKEIKTFLDRFKVEYQDIIEKKELVSLAINLHQAFTQFKQQNGAYGNITPDKRHLE--CNICMDALINCVFLECCHSTCCYSCGSQMTFCPTCRGNIKQCLKIW 998
            C  C K FC L C  +EN RIC  C+ + AT   +  L +  +K LR      N+P     EK+ ++D +L               +  +S        +  +   ++ DMG   S     LD      E   Q ++ +    S++ S ++                  I  LS++++K  L R  V Y    EK ELV     L++   + ++   +YG I P     +  C ICMDA I+CV LEC H   C  CG +M  CP CR  + + + ++
Sbjct:   83 CCDCRKSFCFLCCVLQENLRICATCHLLKATAFQRPRLMRLRVKDLRQYLQLRNIPTDTCREKEDLVDLVLRHQGIEEEEEDDPDAASLRSRSLYTAAPSTTQSASELSDMGDATSVSLLNLDPNEHTPEGSPQMRRRARASLSDISSLRD------------------IEGLSVRQLKEILARNFVNYSGCCEKWELVERVSRLYR---ETEENRKSYGEICPLTIRDDNLCRICMDATIDCVLLECGHMVTCTKCGKRMNECPICRQYVVRAVHVF 339
[Close]
BLAST of Ring finger protein 34b vs. Ensembl Cavefish
Match: rffl (ring finger and FYVE like domain containing E3 ubiquitin protein ligase [Source:NCBI gene;Acc:103042005])

HSP 1 Score: 75.485 bits (184), Expect = 8.396e-15
Identity = 73/278 (26.26%), Postives = 121/278 (43.53%), Query Frame = 3 
Query:  216 RERKLIQCVFCDKEFCLSCTGKE--NTRICCKCNFVIATGIDKEVLKQFSIKQLRILTDNYNVPLKAINEKDQMIDAILVSFKKSIKNN-----NQIVNVNELKQKMIDMGIKDSLDKERKL-----EEEKIQSKKFSDYSNVGSEKNHXXXXXXXXXXXXXXXXXXXXXXXKEIKTFLDRFKVEYQDIIEKKELVSLAINLHQAFTQFKQ-----QNGAYGNITPDKRHLECNICMDALINCVFLECCHSTCCYSCGSQMTFCPTCRGNIKQCLKIW 998
            R RK I CV C K FC  C+ +   + R+C  C+    T  ++  L +  +K LR     + VP +   EK++++D +L     +   +     N +   +E +   +          + +       E   QS+   D  +  SE+  L     +S S   S++DI  LS++++K  L R  V Y+   EK EL+     L+      +       +G    + P      C ICMD+ I+CV LEC H   C  CG +M  CP CR  + + + ++
Sbjct:   59 RARKHI-CVDCKKSFCGHCSAQREAHPRMCHTCHRFHGTMFERAELMKLKVKDLRDYLHLHEVPTQMCREKEELVDLVLGQHTPTSDTSTPTPLNDLTPSSEQEAPSVPTPATTQPQHQPRTGSSATTEVPSQSQATGDEQSSDSEEV-LPPGRRASLSDLNSVEDIEALSVRQLKEILARNFVNYKGCCEKWELMERVTRLYHDQKDLQNLVSNTSDGTDTTVGPSGEENLCKICMDSPIDCVLLECGHMVTCTKCGKRMNECPICRQYVVRAVHVF 334
[Close]
BLAST of Ring finger protein 34b vs. Ensembl Cavefish
Match: rnf34b (ring finger protein 34b [Source:ZFIN;Acc:ZDB-GENE-071004-31])

HSP 1 Score: 67.3958 bits (163), Expect = 4.207e-12
Identity = 68/288 (23.61%), Postives = 118/288 (40.97%), Query Frame = 3 
Query:  192 CDICKNISRERKLIQCVFCDKEFCLSCTG-KENTRICCKCNFVIATGIDKEVLKQFSIKQLRILTDNYNVPLKAINEKDQMIDAILVSFKKSIK--------------NNNQIVNVNELKQKMIDMGIKDSL---DKERKLEEEKI-QSKKFSDYSNVGSEKNHXXXXXXXXXXXXXXXXXXXXXXXKEIKTFLDRFKVEYQDIIEKKELVSLAINLHQAFTQFKQQNGAYGNITPDKRHLECNICMDALINCVFLECCHSTCCYSCGSQMTFCPTCRGNIKQCLKIW 998
            C +  ++ R + +  C  C K FC  C+  +EN R C  C+ +  T   +  L +  +K LR      N+      EK+ +++ +L      ++                 + V  + L  +  D      L     ER LE   + Q +  +  S++  E++                  I  L+++++K  L R  V +    EK ELV     +H+ + +  Q N    ++        C ICMDA+I+CV LEC H   C  CG +M  CP CR  + + + ++
Sbjct:   75 CGLAFSVFRRKHV--CSDCKKSFCSLCSVLQENLRRCVTCHLLWGTAFQRRRLMRLRVKDLRQYLRLRNISTDTCREKEDLVELVLRHLGAELQLPEDQEDQEEEEEEEEEEEVASDSLHLEQGDSASVSLLTLEPSERLLESSPVVQRRARASLSDLAREED------------------IEVLTVRQLKEILARNFVNFSGCCEKWELVE---RVHRLYRE-SQINRISPHLVLQLDENLCRICMDAVIDCVLLECGHMVTCTKCGKRMNECPICRQYVVRAVHVF 338
[Close]
BLAST of Ring finger protein 34b vs. Ensembl Cavefish
Match: rffl (ring finger and FYVE like domain containing E3 ubiquitin protein ligase [Source:NCBI gene;Acc:103042005])

HSP 1 Score: 56.9954 bits (136), Expect = 1.076e-8
Identity = 32/106 (30.19%), Postives = 49/106 (46.23%), Query Frame = 3 
Query:  696 KEIKTFLDRFKVEYQDIIEKKELVSLAINLHQAFTQFKQ-----QNGAYGNITPDKRHLECNICMDALINCVFLECCHSTCCYSCGSQMTFCPTCRGNIKQCLKIW 998
            +++K  L R  V Y+   EK EL+     L+      +       +G    + P      C ICMD+ I+CV LEC H   C  CG +M  CP CR  + + + ++
Sbjct:  253 RQLKEILARNFVNYKGCCEKWELMERVTRLYHDQKDLQNLVSNTSDGTDTTVGPSGEENLCKICMDSPIDCVLLECGHMVTCTKCGKRMNECPICRQYVVRAVHVF 358
[Close]
BLAST of Ring finger protein 34b vs. Ensembl Cavefish
Match: rffl (ring finger and FYVE like domain containing E3 ubiquitin protein ligase [Source:NCBI gene;Acc:103042005])

HSP 1 Score: 56.9954 bits (136), Expect = 1.076e-8
Identity = 32/106 (30.19%), Postives = 49/106 (46.23%), Query Frame = 3 
Query:  696 KEIKTFLDRFKVEYQDIIEKKELVSLAINLHQAFTQFKQ-----QNGAYGNITPDKRHLECNICMDALINCVFLECCHSTCCYSCGSQMTFCPTCRGNIKQCLKIW 998
            +++K  L R  V Y+   EK EL+     L+      +       +G    + P      C ICMD+ I+CV LEC H   C  CG +M  CP CR  + + + ++
Sbjct:  253 RQLKEILARNFVNYKGCCEKWELMERVTRLYHDQKDLQNLVSNTSDGTDTTVGPSGEENLCKICMDSPIDCVLLECGHMVTCTKCGKRMNECPICRQYVVRAVHVF 358
[Close]
BLAST of Ring finger protein 34b vs. Ensembl Cavefish
Match: rffl (ring finger and FYVE like domain containing E3 ubiquitin protein ligase [Source:NCBI gene;Acc:103042005])

HSP 1 Score: 56.6102 bits (135), Expect = 1.345e-8
Identity = 32/101 (31.68%), Postives = 48/101 (47.52%), Query Frame = 3 
Query:  696 KEIKTFLDRFKVEYQDIIEKKELVSLAINLHQAFTQFKQQNGAYGNITPDKRHLECNICMDALINCVFLECCHSTCCYSCGSQMTFCPTCRGNIKQCLKIW 998
            +++K  L R  V Y+   EK EL+     L+      +  +   G   P      C ICMD+ I+CV LEC H   C  CG +M  CP CR  + + + ++
Sbjct:  253 RQLKEILARNFVNYKGCCEKWELMERVTRLYHDQKDLQNLDTTVG---PSGEENLCKICMDSPIDCVLLECGHMVTCTKCGKRMNECPICRQYVVRAVHVF 350
[Close]
BLAST of Ring finger protein 34b vs. Ensembl Sea Lamprey
Match: rffl (ring finger and FYVE-like domain containing E3 ubiquitin protein ligase [Source:ZFIN;Acc:ZDB-GENE-040426-2274])

HSP 1 Score: 61.6178 bits (148), Expect = 7.771e-11
Identity = 37/107 (34.58%), Postives = 54/107 (50.47%), Query Frame = 3 
Query:  696 KEIKTFLDRFKVEYQDIIEKKELVSLAINLHQAFTQF------KQQNGAYGNITPDKRHLECNICMDALINCVFLECCHSTCCYSCGSQMTFCPTCRGNIKQCLKIW 998
            +E+KT L R  V+Y+   E+ EL      L++   Q        Q+NG      P   +  C ICMDA I+CV LEC H   C  CG +M+ CP CR  + + + ++
Sbjct:  280 REMKTLLRRNFVDYKGCCERWELEERVRRLYRDTRQLDKTEMRHQRNGIRLTGGPPDENT-CKICMDAPIDCVLLECGHMVTCTKCGKRMSECPICRQYVVRAVHVF 385
[Close]
BLAST of Ring finger protein 34b vs. Ensembl Nematostella
Match: EDO44591 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RV74])

HSP 1 Score: 63.1586 bits (152), Expect = 3.102e-11
Identity = 66/295 (22.37%), Postives = 113/295 (38.31%), Query Frame = 3 
Query:  192 CDICK-NISRERKLIQCVFCDKEFCLSC-----TGKENTRICCKCNFVIATGIDKEVLKQFSIKQLRILTDNYNVPLKAINEKDQMIDAILVSFKKSIKNNNQIVNVNELKQKMIDMGIKDSLDKERKLEEEKIQSKKFSDYSNVGSEKNHXXXXXXXXXXXXXXXXXXXXX----------------XXKEIKTFLDRFKVEYQDIIEKKELVSLAINLHQAFTQFKQQN----GAYGNITPDKRHLECNICMDALINCVFLECCHSTCCYSCGSQMTFCPTCRGNIKQCLKIW 998
            C +C  N +  ++   C  C K  C +C       ++ +  C  C  + A    K+ L+   IK L+      N+P+    EK  +I+ IL          +Q     +  +         + D+ +        S + ++  N   E N    +            D                    S+KE+K  L    V+++  +EK+EL+S    L ++    KQ+       +G          C +CMD LI+CV LEC H   C +C  Q+  CP CR NI + ++++
Sbjct:   15 CYLCSVNFTLFKRKSTCRGCKKTLCSNCFTQGLNARDQSPRCITCRALAAPSTHKDFLQYLKIKDLQDFLRLKNIPMSQCKEKRDLIELIL--------QYSQPRRYPDFPRGTPHPPPPVTHDQRQGGTHPNSNSGQTANRVNRAGENNASGGEGQQILLSLPPPPDFFATRRTIDDITDIEQVDNLSVKELKHILTANFVDFKGCVEKEELLSKVRLLWKSRNCEKQKGMFALPGFGLFNTTSLDESCKVCMDNLIDCVLLECGHMVACINCSKQLAECPICRQNISRIVRVF 301
[Close]
BLAST of Ring finger protein 34b vs. Ensembl Nematostella
Match: EDO30381 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T0Y6])

HSP 1 Score: 52.7582 bits (125), Expect = 8.318e-8
Identity = 20/47 (42.55%), Postives = 28/47 (59.57%), Query Frame = 3 
Query:  861 CNICMDALINCVFLECCHSTCCYSCGSQMTFCPTCRGNIKQCLKIWI 1001
            C ICMDA +  VFL C H +CC  C   M  CP CR  I++ ++ ++
Sbjct:  285 CKICMDAEVGIVFLPCGHLSCCPGCAEGMELCPMCRAPIRETIRTFL 331
[Close]
BLAST of Ring finger protein 34b vs. Ensembl Nematostella
Match: EDO41568 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S3Y5])

HSP 1 Score: 50.0618 bits (118), Expect = 7.747e-7
Identity = 20/49 (40.82%), Postives = 25/49 (51.02%), Query Frame = 3 
Query:  855 LECNICMDALINCVFLECCHSTCCYSCGSQMTFCPTCRGNIKQCLKIWI 1001
            L C +CMD  IN V + C H  CC  C   +  CP CRG I    K ++
Sbjct:  375 LRCKVCMDEQINAVLIPCGHMVCCEQCAMNLEACPVCRGAIDHVQKAFL 423
[Close]
BLAST of Ring finger protein 34b vs. Ensembl Nematostella
Match: EDO43423 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RYU6])

HSP 1 Score: 47.3654 bits (111), Expect = 7.678e-6
Identity = 18/49 (36.73%), Postives = 28/49 (57.14%), Query Frame = 3 
Query:  858 ECNICMDALINCVFLECCHSTCCYSCGSQMTFCPTCRGNIKQCLKIWIG 1004
            EC IC+D   + V L C H  CC +C   ++ CP CR  + Q ++++I 
Sbjct:  697 ECVICLDNRSDVVMLPCGHVCCCSNCAGAVSACPICRQTLSQRVRMYIS 745
[Close]
BLAST of Ring finger protein 34b vs. Ensembl Medaka
Match: rnf34a (ring finger protein 34 [Source:NCBI gene;Acc:101157222])

HSP 1 Score: 85.5001 bits (210), Expect = 3.526e-18
Identity = 75/278 (26.98%), Postives = 117/278 (42.09%), Query Frame = 3 
Query:  237 CVFCDKEFC-LSCTGKENTRICCKCNFVIATGIDKEVLKQFSIKQLRILTDNYNVPLKAINEKDQMIDAIL--------------VSFKKSIKNNNQIVNVNELKQKMIDMGIKDS-----LDKERKLEEEKIQSKKFS--DYSNVGSEKNHXXXXXXXXXXXXXXXXXXXXXXXKEIKTFLDRFKVEYQDIIEKKELVSLAINLHQAFTQFKQQNGAYGNITPDKRHLE--CNICMDALINCVFLECCHSTCCYSCGSQMTFCPTCRGNIKQCLKIW 998
            C  C K FC L C  +EN RIC  C+ + AT   +  L +  +K LR      N+P     EK+ ++D +L               +  +S        +  +   ++ DMG   S     LD      E   Q ++ +    S++ S ++                  I  LS++++K  L R  V Y    EK ELV     L++   + ++   +YG I P     +  C ICMDA I+CV LEC H   C  CG +M  CP CR  + + + ++
Sbjct:   83 CCDCRKSFCFLCCVLQENLRICATCHLLKATAFQRPRLMRLRVKDLRQYLQLRNIPTDTCREKEDLVDLVLRHQGIEEEEEDDPDAASLRSRSLYTAAPSTTQSASELSDMGDATSVSLLNLDPNEHTPEGSPQMRRRARASLSDISSLRD------------------IEGLSVRQLKEILARNFVNYSGCCEKWELVERVSRLYR---ETEENRKSYGEICPLTIRDDNLCRICMDATIDCVLLECGHMVTCTKCGKRMNECPICRQYVVRAVHVF 339
[Close]
BLAST of Ring finger protein 34b vs. Ensembl Medaka
Match: rnf34a (ring finger protein 34 [Source:NCBI gene;Acc:101157222])

HSP 1 Score: 78.9518 bits (193), Expect = 7.201e-16
Identity = 79/284 (27.82%), Postives = 124/284 (43.66%), Query Frame = 3 
Query:  237 CVFCDKEFC-LSCTGKENTRICCKCNFVIATGIDKEVLKQFSIKQLRILTDNYNVPLKAINEKDQMIDAILVSFKKSIKNNNQIVNVNELKQKMIDMGIKDSLDKERKLE-----EEKIQSKKFSDYSNVGSEKNHXXXXXXXXXXXXXXXXXXXXXXXKEIKTFLDRFKVEYQDIIEKKELVSLAINLHQAFTQFKQQ-------------------NGAYGN-----ITPDKRHLECNICMDALINCVFLECCHSTCCYSCGSQMTFCPTCRGNIKQCLKIW 998
            C  C K FC L C  +EN RIC  C+ + AT   +  L +  +K LR      N+P     EK+ ++D +L   +   +      +   L+ + +      +     +L      +E+  S+  S  +N GS +  +     +S S   SL DI  LS++++K  L R  V Y    EK ELV     L++   + ++                    NGA G+     +T    +L C ICMDA I+CV LEC H   C  CG +M  CP CR  + + + ++
Sbjct:   92 CCDCRKSFCFLCCVLQENLRICATCHLLKATAFQRPRLMRLRVKDLRQYLQLRNIPTDTCREKEDLVDLVL-RHQGIEEEEEDDPDAASLRSRSLYTAAPSTTQSASELSAFAASQEEPLSRSDSSDTNQGSPQ--MRRRARASLSDISSLRDIEGLSVRQLKEILARNFVNYSGCCEKWELVERVSRLYRETEENRKSLENVSSTVTSVMAFPPPICNGAIGDGEICPLTIRDDNL-CRICMDATIDCVLLECGHMVTCTKCGKRMNECPICRQYVVRAVHVF 371
[Close]
BLAST of Ring finger protein 34b vs. Ensembl Medaka
Match: rnf34a (ring finger protein 34 [Source:NCBI gene;Acc:101157222])

HSP 1 Score: 71.2478 bits (173), Expect = 2.846e-13
Identity = 71/288 (24.65%), Postives = 111/288 (38.54%), Query Frame = 3 
Query:  237 CVFCDKEFC-LSCTGKENTRICCKCNFVIATGIDKEVLKQFSIKQLRILTDNYNVPLKAINEKDQMIDAILVSFKKSIKNNNQIVNVNELKQKMIDMGIKDSLDKERKL------EEEKIQSKKFSD----------YSNVGSEKNHXXXXXXXXXXXXXXXXXXXXXXXKEI--------KTFLDRFKVEYQDIIEKKELVSLAINLHQ-------AFTQFKQQNGAYGNITPDKRHLE--CNICMDALINCVFLECCHSTCCYSCGSQMTFCPTCRGNIKQCLKIW 998
            C  C K FC L C  +EN RIC  C+ + AT   +  L +  +K LR      N+P     EK+ ++D +L   +   +      +   L+ + +      +     +L      +EE +     SD           S +  + N  + + S               S+++I        K  L R  V Y    EK ELV     L++       +         + G I P     +  C ICMDA I+CV LEC H   C  CG +M  CP CR  + + + ++
Sbjct:   92 CCDCRKSFCFLCCVLQENLRICATCHLLKATAFQRPRLMRLRVKDLRQYLQLRNIPTDTCREKEDLVDLVL-RHQGIEEEEEDDPDAASLRSRSLYTAAPSTTQSASELSAFAASQEEPLSRSDSSDTNQDMGDATSVSLLNLDPNEHTPEGSPQMRRRARASLSDISSLRDIEGLSVRQLKEILARNFVNYSGCCEKWELVERVSRLYRETEENRKSLENVSSTVTSDGEICPLTIRDDNLCRICMDATIDCVLLECGHMVTCTKCGKRMNECPICRQYVVRAVHVF 378
[Close]
BLAST of Ring finger protein 34b vs. Ensembl Medaka
Match: rnf34a (ring finger protein 34 [Source:NCBI gene;Acc:101157222])

HSP 1 Score: 70.0922 bits (170), Expect = 6.455e-13
Identity = 74/303 (24.42%), Postives = 117/303 (38.61%), Query Frame = 3 
Query:  237 CVFCDKEFC-LSCTGKENTRICCKCNFVIATGIDKEVLKQFSIKQLRILTDNYNVPLKAINEKDQMIDAILVSFKKSIKNNNQIVNVNELKQKMIDMGIKDSLDKERKL------EEEKIQSKKFSD----------YSNVGSEKNHXXXXXXXXXXXXXXXXXXXXXXXKEI--------KTFLDRFKVEYQDIIEKKELVSLAINLHQAFTQFKQQ-------------------NGAYGN-----ITPDKRHLECNICMDALINCVFLECCHSTCCYSCGSQMTFCPTCRGNIKQCLKIW 998
            C  C K FC L C  +EN RIC  C+ + AT   +  L +  +K LR      N+P     EK+ ++D +L   +   +      +   L+ + +      +     +L      +EE +     SD           S +  + N  + + S               S+++I        K  L R  V Y    EK ELV     L++   + ++                    NGA G+     +T    +L C ICMDA I+CV LEC H   C  CG +M  CP CR  + + + ++
Sbjct:   92 CCDCRKSFCFLCCVLQENLRICATCHLLKATAFQRPRLMRLRVKDLRQYLQLRNIPTDTCREKEDLVDLVL-RHQGIEEEEEDDPDAASLRSRSLYTAAPSTTQSASELSAFAASQEEPLSRSDSSDTNQDMGDATSVSLLNLDPNEHTPEGSPQMRRRARASLSDISSLRDIEGLSVRQLKEILARNFVNYSGCCEKWELVERVSRLYRETEENRKSLENVSSTVTSVMAFPPPICNGAIGDGEICPLTIRDDNL-CRICMDATIDCVLLECGHMVTCTKCGKRMNECPICRQYVVRAVHVF 392
[Close]
BLAST of Ring finger protein 34b vs. Ensembl Medaka
Match: rffl (ring finger and FYVE like domain containing E3 ubiquitin protein ligase [Source:NCBI gene;Acc:101160886])

HSP 1 Score: 68.5514 bits (166), Expect = 1.621e-12
Identity = 73/303 (24.09%), Postives = 117/303 (38.61%), Query Frame = 3 
Query:  177 ASSNRCDICKN-ISRERKLIQCVFCDKEFCLSCTGK--ENTRICCKCNFVIATGIDKEVLKQFSIKQLRILTDNYNVPLKAINEKDQMIDAILVSFKKSIKNNNQIVNVNELKQKMIDM-------------------GIKDSLDKERKLEEEKIQSKKFSDYSNVGSEKNHXXXXXXXXXXXXXXXXXXXXXXXKEIKTFLDRFKVEYQDIIEKKELVSLAINLHQAFTQFKQQN-------GAYGNITPDKRHLECNICMDALINCVFLECCHSTCCYSCGSQMTFCPTCRGNIKQCLKIW 998
            +  + C+ CK       K   CV C K +C  C+ +     R+C  C       +++  L +  +K+LR     + VP     EK++++D +L        ++     + E      D                    G     +    L E         +   V            +S S     +DI  LS++++K  L R  V+Y+   EK EL+     L+Q      QQN       G    IT  +  L C ICMD+ I+CV LEC H   C  CG +M+ CP CR  + + + ++
Sbjct:   36 SPEHSCEACKGRFDTHTKKHTCVDCKKNYCNRCSAQMGPRPRLCHTCQHFYGKLLERAELMKLKVKELRHYLHLHEVPTHLCREKEELVDLVLGQQSSPSSSSTPETPITEAPSMTFDPPLIPHTSAAFAAAPPSPPEGQSAESEVPPPLVETAPPEPDPQEDDQVWDGDEAPVWGRRASLSDLSGPEDIEALSVRQLKEILARNFVDYKGCCEKWELMERVTRLYQ-----DQQNLLEATSVGTADAITALEDGL-CRICMDSPIDCVLLECGHMITCAKCGKRMSECPICRQFVVRAVHVF 332
[Close]
BLAST of Ring finger protein 34b vs. Planmine SMEST
Match: SMESG000045336.1 (SMESG000045336.1)

HSP 1 Score: 513.842 bits (1322), Expect = 0.000e+0
Identity = 300/301 (99.67%), Postives = 301/301 (100.00%), Query Frame = 3 
Query:  102 MDDXXXXXXXXXXXXXXXXAELIEVASSNRCDICKNISRERKLIQCVFCDKEFCLSCTGKENTRICCKCNFVIATGIDKEVLKQFSIKQLRILTDNYNVPLKAINEKDQMIDAILVSFKKSIKNNNQIVNVNELKQKMIDMGIKDSLDKERKLEEEKIQSKKFSDYSNVGSEKNHXXXXXXXXXXXXXXXXXXXXXXXKEIKTFLDRFKVEYQDIIEKKELVSLAINLHQAFTQFKQQNGAYGNITPDKRHLECNICMDALINCVFLECCHSTCCYSCGSQMTFCPTCRGNIKQCLKIWIG 1004
            MDDLLLAKLILLTKRPLLLAELIEVASSNRCDICKNISR+RKLIQCVFCDKEFCLSCTGKENTRICCKCNFVIATGIDKEVLKQFSIKQLRILTDNYNVPLKAINEKDQMIDAILVSFKKSIKNNNQIVNVNELKQKMIDMGIKDSLDKERKLEEEKIQSKKFSDYSNVGSEKNHLSVDFSSSDSIDISLDDIPKLSIKEIKTFLDRFKVEYQDIIEKKELVSLAINLHQAFTQFKQQNGAYGNITPDKRHLECNICMDALINCVFLECCHSTCCYSCGSQMTFCPTCRGNIKQCLKIWIG
Sbjct:    1 MDDLLLAKLILLTKRPLLLAELIEVASSNRCDICKNISRDRKLIQCVFCDKEFCLSCTGKENTRICCKCNFVIATGIDKEVLKQFSIKQLRILTDNYNVPLKAINEKDQMIDAILVSFKKSIKNNNQIVNVNELKQKMIDMGIKDSLDKERKLEEEKIQSKKFSDYSNVGSEKNHLSVDFSSSDSIDISLDDIPKLSIKEIKTFLDRFKVEYQDIIEKKELVSLAINLHQAFTQFKQQNGAYGNITPDKRHLECNICMDALINCVFLECCHSTCCYSCGSQMTFCPTCRGNIKQCLKIWIG 301
[Close]
BLAST of Ring finger protein 34b vs. Planmine SMEST
Match: SMESG000049534.1 (SMESG000049534.1)

HSP 1 Score: 83.1889 bits (204), Expect = 1.780e-17
Identity = 77/312 (24.68%), Postives = 140/312 (44.87%), Query Frame = 3 
Query:  180 SSNRCDICKN----ISRERKLIQCVFCDKEFCLSCT--GKENTRICCKCNFVIATGIDKEVLKQFSIKQLRILTDNYNVPLKAINEKDQMIDAILVSFKKSIKNN-----NQIVNVNELKQKM-------------------------IDMGIKDSLDKERKLEE-EKIQSKKFSDYSNVGSEKNHXXXXXXXXXXXXXXXXXXXXXXXKEIKTFLDRFKVEYQDIIEKKELVSLAINLHQAFTQFKQQNGAYGNITPDKRHL--ECNICMDALINCVFLECCHSTCCYSCGSQMTFCPTCRGNIKQCLKIW 998
            S N+C  C+     IS +++  +CV C + +C+ C    KE+  IC +C   ++       L +   K L    +  N+   +  EK+Q+++ IL  F     N      +++VN NE    +                         I  G   S  +  K+   ++I    + +    G   + ++           ++D+I  LSI+++K  L   KV+Y+  +E+ ELVS    + + +T +  +   +    P+K     EC ICMD+ ++CV +EC H  CC  CGS++  CP CR N+ +C++++
Sbjct:   36 SPNKCVACQAAFNFISFKKR--KCVNCMENYCVDCVMHYKESIYICYRCQIFMSPNFGWSELMKLKSKDLIWYLNRRNISCSSCKEKEQLVELILEKFNLPSNNKRFNIVDELVNQNERVANITPDSTNTINPNDADSSSCNLSQTDNISNGASSSCQQTNKIPGFQRIPPPTYEEAMEGGYPASVINRAERVPIEDISAIDEIELLSIRQLKDMLAYNKVDYKGCVERYELVS---RVKRLWTAYNNERNDFQTENPNKSEPVKECAICMDSPVDCVLIECGHMLCCVRCGSKLAECPICRQNVVRCIRVF 342
The following BLAST results are available for this feature:
BLAST of Ring finger protein 34b vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
RFFL3.786e-1123.68ring finger and FYVE like domain containing E3 ubi... [more]
RNF346.510e-1132.67ring finger protein 34 [Source:HGNC Symbol;Acc:HGN... [more]
RNF341.713e-932.67ring finger protein 34 [Source:HGNC Symbol;Acc:HGN... [more]
RNF341.819e-932.67ring finger protein 34 [Source:HGNC Symbol;Acc:HGN... [more]
RFFL2.576e-934.69ring finger and FYVE like domain containing E3 ubi... [more]
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BLAST of Ring finger protein 34b vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Ring finger protein 34b vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 4
Match NameE-valueIdentityDescription
CG170192.936e-834.65gene:FBgn0033783 transcript:FBtr0087806[more]
CG170192.936e-834.65gene:FBgn0033783 transcript:FBtr0339738[more]
dnr11.421e-642.86gene:FBgn0260866 transcript:FBtr0071837[more]
dnr11.851e-642.86gene:FBgn0260866 transcript:FBtr0330229[more]
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BLAST of Ring finger protein 34b vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rffl9.047e-1323.51ring finger and FYVE-like domain containing E3 ubi... [more]
rffl7.690e-1223.13ring finger and FYVE-like domain containing E3 ubi... [more]
rnf34a6.173e-1024.67ring finger protein 34a [Source:ZFIN;Acc:ZDB-GENE-... [more]
zgc:1717404.949e-830.56zgc:171740 [Source:ZFIN;Acc:ZDB-GENE-071004-29][more]
zgc:1717404.949e-830.56zgc:171740 [Source:ZFIN;Acc:ZDB-GENE-071004-29][more]
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BLAST of Ring finger protein 34b vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dctn26.300e-1122.51dynactin subunit 2 [Source:Xenbase;Acc:XB-GENE-100... [more]
dctn21.163e-1022.76dynactin subunit 2 [Source:Xenbase;Acc:XB-GENE-100... [more]
prlr4.311e-832.73prolactin receptor [Source:Xenbase;Acc:XB-GENE-494... [more]
prlr4.628e-831.82prolactin receptor [Source:Xenbase;Acc:XB-GENE-494... [more]
prlr5.055e-831.82prolactin receptor [Source:Xenbase;Acc:XB-GENE-494... [more]
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BLAST of Ring finger protein 34b vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Rffl1.927e-1124.73ring finger and FYVE like domain containing protei... [more]
Rnf341.515e-932.67ring finger protein 34 [Source:MGI Symbol;Acc:MGI:... [more]
Rffl1.211e-731.48ring finger and FYVE like domain containing protei... [more]
Rffl1.211e-731.48ring finger and FYVE like domain containing protei... [more]
Rffl1.258e-731.48ring finger and FYVE like domain containing protei... [more]
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BLAST of Ring finger protein 34b vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q969K3|RNF34_HUMAN7.294e-932.67E3 ubiquitin-protein ligase RNF34 OS=Homo sapiens ... [more]
sp|Q5NVC7|RNF34_PONAB7.562e-932.67E3 ubiquitin-protein ligase RNF34 OS=Pongo abelii ... [more]
sp|Q5E9J6|RNF34_BOVIN7.921e-932.67E3 ubiquitin-protein ligase RNF34 OS=Bos taurus OX... [more]
sp|Q99KR6|RNF34_MOUSE8.541e-932.67E3 ubiquitin-protein ligase RNF34 OS=Mus musculus ... [more]
sp|Q6AYH3|RNF34_RAT9.083e-932.67E3 ubiquitin-protein ligase RNF34 OS=Rattus norveg... [more]
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BLAST of Ring finger protein 34b vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A3P8Z6611.419e-1525.47Ring finger protein 34a OS=Esox lucius OX=8010 PE=... [more]
A0A3Q4G4I91.810e-1526.06Ring finger protein 34b OS=Neolamprologus brichard... [more]
A0A3P8STA54.290e-1527.94Ring finger protein 34a OS=Amphiprion percula OX=1... [more]
A0A3Q1AJS25.714e-1527.94Ring finger protein 34a OS=Amphiprion ocellaris OX... [more]
A0A3P9LQJ71.021e-1426.98Ring finger protein 34a OS=Oryzias latipes OX=8090... [more]
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BLAST of Ring finger protein 34b vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rffl8.396e-1526.26ring finger and FYVE like domain containing E3 ubi... [more]
rnf34b4.207e-1223.61ring finger protein 34b [Source:ZFIN;Acc:ZDB-GENE-... [more]
rffl1.076e-830.19ring finger and FYVE like domain containing E3 ubi... [more]
rffl1.076e-830.19ring finger and FYVE like domain containing E3 ubi... [more]
rffl1.345e-831.68ring finger and FYVE like domain containing E3 ubi... [more]
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BLAST of Ring finger protein 34b vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
rffl7.771e-1134.58ring finger and FYVE-like domain containing E3 ubi... [more]
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BLAST of Ring finger protein 34b vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Ring finger protein 34b vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 4
Match NameE-valueIdentityDescription
EDO445913.102e-1122.37Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO303818.318e-842.55Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO415687.747e-740.82Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO434237.678e-636.73Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Ring finger protein 34b vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rnf34a3.526e-1826.98ring finger protein 34 [Source:NCBI gene;Acc:10115... [more]
rnf34a7.201e-1627.82ring finger protein 34 [Source:NCBI gene;Acc:10115... [more]
rnf34a2.846e-1324.65ring finger protein 34 [Source:NCBI gene;Acc:10115... [more]
rnf34a6.455e-1324.42ring finger protein 34 [Source:NCBI gene;Acc:10115... [more]
rffl1.621e-1224.09ring finger and FYVE like domain containing E3 ubi... [more]
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BLAST of Ring finger protein 34b vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 2
Match NameE-valueIdentityDescription
SMESG000045336.10.000e+099.67SMESG000045336.1[more]
SMESG000049534.11.780e-1724.68SMESG000049534.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30019292 ID=SMED30019292|Name=Ring finger protein 34b|organism=Schmidtea mediterranea sexual|type=transcript|length=1137bp
GTTTTACTTATCTTAGGTCAAAATTATAGATCCGCTAAATTTTGTAAACT
GACTTTTTATAACTATTTTTATCAGGTAAATTATTTACTAATTTACCTTC
TATGGATGATTTGTTACTGGCAAAACTCATTTTATTGACTAAAAGACCGT
TGTTGCTTGCTGAGCTAATTGAAGTTGCTTCTTCAAATAGATGTGATATT
TGCAAAAATATCTCAAGGGAAAGAAAATTAATTCAATGCGTTTTCTGTGA
TAAAGAGTTTTGTTTATCTTGCACGGGAAAAGAAAATACCCGAATTTGTT
GCAAATGTAATTTTGTCATTGCTACAGGTATTGATAAAGAGGTTCTGAAA
CAATTTTCTATCAAGCAGTTAAGAATATTAACTGATAATTATAATGTTCC
TTTAAAAGCTATTAATGAAAAAGATCAAATGATTGATGCAATCTTGGTCA
GTTTTAAAAAATCTATTAAAAATAACAATCAAATTGTTAATGTAAATGAA
TTGAAACAAAAAATGATAGATATGGGAATTAAAGATAGTCTTGATAAAGA
AAGAAAACTTGAGGAAGAAAAAATTCAATCGAAAAAGTTTTCTGACTACT
CAAATGTTGGCAGTGAAAAAAATCACTTGTCTGTTGATTTTAGCTCTAGT
GATTCGATTGATATTTCATTGGATGATATTCCAAAATTGTCCATAAAAGA
AATAAAAACTTTTTTAGATCGTTTTAAAGTCGAATATCAAGATATTATAG
AAAAGAAAGAATTGGTTTCGTTGGCAATTAATTTGCATCAGGCATTCACA
CAATTCAAGCAGCAAAATGGTGCTTACGGAAATATTACTCCCGATAAAAG
GCACTTGGAATGCAATATTTGCATGGATGCGTTAATTAATTGTGTTTTTC
TTGAGTGCTGTCATTCCACGTGTTGCTACAGTTGCGGAAGTCAGATGACC
TTCTGTCCGACCTGTCGGGGGAATATCAAACAATGTCTTAAAATTTGGAT
CGGATAATTTGATATTAACTATCTACTCTTTTAACTATGGAAATTTTTCA
TTACTTTAATGAGCTTTCGATAATTTTGGATTTAATTTTTAATGTATAAA
TAAAAGAAATAATAAAACAAACTTTTTAACATGTGCT
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protein sequence of SMED30019292-orf-1

>SMED30019292-orf-1 ID=SMED30019292-orf-1|Name=SMED30019292-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=302bp
MDDLLLAKLILLTKRPLLLAELIEVASSNRCDICKNISRERKLIQCVFCD
KEFCLSCTGKENTRICCKCNFVIATGIDKEVLKQFSIKQLRILTDNYNVP
LKAINEKDQMIDAILVSFKKSIKNNNQIVNVNELKQKMIDMGIKDSLDKE
RKLEEEKIQSKKFSDYSNVGSEKNHLSVDFSSSDSIDISLDDIPKLSIKE
IKTFLDRFKVEYQDIIEKKELVSLAINLHQAFTQFKQQNGAYGNITPDKR
HLECNICMDALINCVFLECCHSTCCYSCGSQMTFCPTCRGNIKQCLKIWI
G*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0046872metal ion binding
GO:0005515protein binding
GO:0008270zinc ion binding
GO:0016874ligase activity
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0000034epidermis
PLANA:0000070intestinal phagocyte
PLANA:0000099neuron
PLANA:0002032epidermal cell
Vocabulary: INTERPRO
TermDefinition
IPR013083Znf_RING/FYVE/PHD
IPR001841Znf_RING
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableGENE3DG3DSA:1.10.720.140coord: 37..117
e-value: 1.3E-9
score: 40.0
NoneNo IPR availablePFAMPF13920zf-C3HC4_3coord: 252..294
e-value: 1.6E-6
score: 27.9
NoneNo IPR availablePANTHERPTHR14879:SF3E3 UBIQUITIN-PROTEIN LIGASE RNF34coord: 118..294
NoneNo IPR availablePANTHERPTHR14879CASPASE REGULATOR, RING FINGER DOMAIN-CONTAININGcoord: 31..136
NoneNo IPR availablePANTHERPTHR14879:SF3E3 UBIQUITIN-PROTEIN LIGASE RNF34coord: 31..136
NoneNo IPR availablePANTHERPTHR14879CASPASE REGULATOR, RING FINGER DOMAIN-CONTAININGcoord: 118..294
NoneNo IPR availableSIGNALP_EUKSignalP-noTMSignalP-noTMcoord: 1..20
score: 0.586
NoneNo IPR availableSUPERFAMILYSSF57850RING/U-boxcoord: 253..294
IPR013083Zinc finger, RING/FYVE/PHD-typeGENE3DG3DSA:3.30.40.10coord: 231..301
e-value: 4.1E-12
score: 47.3
IPR001841Zinc finger, RING-typePROSITEPS50089ZF_RING_2coord: 254..289
score: 10.365