Protein FAM151A

Overview
NameProtein FAM151A
Smed IDSMED30019240
Length (bp)2156
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Protein FAM151A (SMED30019240) t-SNE clustered cells

Violin plots show distribution of expression levels for Protein FAM151A (SMED30019240) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Protein FAM151A (SMED30019240) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Protein FAM151A (SMED30019240) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30019240

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 5

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
head regionSMED30019240SMESG000000164.1 SmedASXL_017148SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
pharynxSMED30019240SMESG000000164.1 dd_Smed_v4_9939_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30019240SMESG000000164.1 dd_Smed_v4_9939_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30019240SMESG000000164.1 dd_Smed_v6_9939_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
epidermisSMED30019240SMESG000000164.1 dd_Smed_v4_9939_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Protein FAM151A vs. Ensembl Human
Match: LRRIQ3 (leucine rich repeats and IQ motif containing 3 [Source:HGNC Symbol;Acc:HGNC:28318])

HSP 1 Score: 153.295 bits (386), Expect = 6.202e-41
Identity = 81/196 (41.33%), Postives = 123/196 (62.76%), Query Frame = 3 
Query:  321 NIQKISSLEYCCNLVYLNLSKNFISDFSALKLCQNLNCLDLSSNLIESLPDFNFWNKISTLKFLYLHDNPIANPDSIMGLCSCPSITLLTLWDSPLALRYKYRHFVVNSVWSLKVLDNHFVSDEEIIEDANFKNSLFRSMSEKLQVNSYQTYNNHDGGAVEI-DLKNFLVRINHLISHLSPVLIIQRWIRGYLIRK 905
            +++ + +L+ C +L     S NFI+D   L+ C  L  LDL  N I+SLP+  FWN +  LK LYLHDN  A   +I  L +CP++  LT++D P++L+  YRH +VNS+W LK LD+H +SDEEII++ +     F++ + +L  N             EI ++K+   +IN +++H SPVLI+QRWIRG+L+RK
Sbjct:   39 HLKSMENLQSCISLRVCIFSNNFITDIHPLQSCIKLIKLDLHGNQIKSLPNTKFWNGLKNLKLLYLHDNGFAKLKNICVLSACPTLIALTMFDCPVSLKKGYRHVLVNSIWPLKALDHHVISDEEIIQNWHLPER-FKACNHRLFFNFCPALRKGTTYEEEINNIKHITSKINAILAHNSPVLIVQRWIRGFLVRK 233
[Close]
BLAST of Protein FAM151A vs. Ensembl Human
Match: LRRIQ3 (leucine rich repeats and IQ motif containing 3 [Source:HGNC Symbol;Acc:HGNC:28318])

HSP 1 Score: 157.532 bits (397), Expect = 6.477e-40
Identity = 81/196 (41.33%), Postives = 123/196 (62.76%), Query Frame = 3 
Query:  321 NIQKISSLEYCCNLVYLNLSKNFISDFSALKLCQNLNCLDLSSNLIESLPDFNFWNKISTLKFLYLHDNPIANPDSIMGLCSCPSITLLTLWDSPLALRYKYRHFVVNSVWSLKVLDNHFVSDEEIIEDANFKNSLFRSMSEKLQVNSYQTYNNHDGGAVEI-DLKNFLVRINHLISHLSPVLIIQRWIRGYLIRK 905
            +++ + +L+ C +L     S NFI+D   L+ C  L  LDL  N I+SLP+  FWN +  LK LYLHDN  A   +I  L +CP++  LT++D P++L+  YRH +VNS+W LK LD+H +SDEEII++ +     F++ + +L  N             EI ++K+   +IN +++H SPVLI+QRWIRG+L+RK
Sbjct:   39 HLKSMENLQSCISLRVCIFSNNFITDIHPLQSCIKLIKLDLHGNQIKSLPNTKFWNGLKNLKLLYLHDNGFAKLKNICVLSACPTLIALTMFDCPVSLKKGYRHVLVNSIWPLKALDHHVISDEEIIQNWHLPER-FKACNHRLFFNFCPALRKGTTYEEEINNIKHITSKINAILAHNSPVLIVQRWIRGFLVRK 233
[Close]
BLAST of Protein FAM151A vs. Ensembl Human
Match: LRRIQ3 (leucine rich repeats and IQ motif containing 3 [Source:HGNC Symbol;Acc:HGNC:28318])

HSP 1 Score: 157.532 bits (397), Expect = 6.477e-40
Identity = 81/196 (41.33%), Postives = 123/196 (62.76%), Query Frame = 3 
Query:  321 NIQKISSLEYCCNLVYLNLSKNFISDFSALKLCQNLNCLDLSSNLIESLPDFNFWNKISTLKFLYLHDNPIANPDSIMGLCSCPSITLLTLWDSPLALRYKYRHFVVNSVWSLKVLDNHFVSDEEIIEDANFKNSLFRSMSEKLQVNSYQTYNNHDGGAVEI-DLKNFLVRINHLISHLSPVLIIQRWIRGYLIRK 905
            +++ + +L+ C +L     S NFI+D   L+ C  L  LDL  N I+SLP+  FWN +  LK LYLHDN  A   +I  L +CP++  LT++D P++L+  YRH +VNS+W LK LD+H +SDEEII++ +     F++ + +L  N             EI ++K+   +IN +++H SPVLI+QRWIRG+L+RK
Sbjct:   39 HLKSMENLQSCISLRVCIFSNNFITDIHPLQSCIKLIKLDLHGNQIKSLPNTKFWNGLKNLKLLYLHDNGFAKLKNICVLSACPTLIALTMFDCPVSLKKGYRHVLVNSIWPLKALDHHVISDEEIIQNWHLPER-FKACNHRLFFNFCPALRKGTTYEEEINNIKHITSKINAILAHNSPVLIVQRWIRGFLVRK 233
[Close]
BLAST of Protein FAM151A vs. Ensembl Human
Match: LRRIQ3 (leucine rich repeats and IQ motif containing 3 [Source:HGNC Symbol;Acc:HGNC:28318])

HSP 1 Score: 119.398 bits (298), Expect = 4.517e-30
Identity = 61/147 (41.50%), Postives = 93/147 (63.27%), Query Frame = 3 
Query:  321 NIQKISSLEYCCNLVYLNLSKNFISDFSALKLCQNLNCLDLSSNLIESLPDFNFWNKISTLKFLYLHDNPIANPDSIMGLCSCPSITLLTLWDSPLALRYKYRHFVVNSVWSLKVLDNHFVSDEEIIEDANFKNSLFRSMSEKLQVN 761
            +++ + +L+ C +L     S NFI+D   L+ C  L  LDL  N I+SLP+  FWN +  LK LYLHDN  A   +I  L +CP++  LT++D P++L+  YRH +VNS+W LK LD+H +SDEEII++ +     F++ + +L  N
Sbjct:   39 HLKSMENLQSCISLRVCIFSNNFITDIHPLQSCIKLIKLDLHGNQIKSLPNTKFWNGLKNLKLLYLHDNGFAKLKNICVLSACPTLIALTMFDCPVSLKKGYRHVLVNSIWPLKALDHHVISDEEIIQNWHLPER-FKACNHRLFFN 184
[Close]
BLAST of Protein FAM151A vs. Ensembl Human
Match: LRRC49 (leucine rich repeat containing 49 [Source:HGNC Symbol;Acc:HGNC:25965])

HSP 1 Score: 66.2402 bits (160), Expect = 1.426e-10
Identity = 45/137 (32.85%), Postives = 75/137 (54.74%), Query Frame = 3 
Query:  285 LKSIKVLILHQQNIQKISSLEYCCNLVYLNLSKNFISDFSALKLCQNLNCLDLSSNLIESLPDFNFWNKISTLKFLYLHDNPIANPDSIMGLCSCPSITLLTLWDSPLALRYKYRHFVVNSVWSLKVLDNHFVSDEE 695
            LKS+ VL LH   I KI ++ + C L  LNL++NF+S    L    +L  L+L  N I  + D    + +  L+ L+L  N I++ DS+  L    S++ +T   +P+A    Y+H V+ ++  L+ LD   +++EE
Sbjct:  182 LKSLDVLDLHGNQITKIENINHLCELRVLNLARNFLSHVDNLNGLDSLTELNLRHNQITFVRDV---DNLPCLQHLFLSFNNISSFDSVSCLADSSSLSDITFDGNPIAQESWYKHTVLQNMMQLRQLDMKRITEEE 315
[Close]
BLAST of Protein FAM151A vs. Ensembl Celegans
Match: F13E9.1 (pep chromosome:WBcel235:IV:10864331:10873632:1 gene:WBGene00008750.1 transcript:F13E9.1.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:F13E9.1)

HSP 1 Score: 49.2914 bits (116), Expect = 8.062e-6
Identity = 39/126 (30.95%), Postives = 64/126 (50.79%), Query Frame = 3 
Query:  270 ESFDLLKSIKVLILHQQNIQKISS-LEYCCNLVYLNLSKNFISDFSAL-KLCQNLNCLDLSSNLIESLPDFNFWNKISTLKFLYLHDNPIANPDSIMGLCSCPSITLLTLWDSPLALRYKYRHFVV 641
            ES  LL  ++VL +   +I +I S L +  +L  L+LS N ++      +   N+  L LS N IE L       K+ +L++L    N I N D++ G+   P + +L L D+P+    +YR  V+
Sbjct:  306 ESMKLLPEVRVLNVSYNSITEIGSNLAFLSSLTELDLSNNTLTKIDGWNEKLGNIKKLILSENAIEDLSGLG---KLYSLEYLDAKGNNIQNLDAVQGIGKLPCLEILLLRDNPIRKLVEYRTKVL 428
[Close]
BLAST of Protein FAM151A vs. Ensembl Zebrafish
Match: lrriq3 (leucine-rich repeats and IQ motif containing 3 [Source:ZFIN;Acc:ZDB-GENE-081104-400])

HSP 1 Score: 133.265 bits (334), Expect = 8.129e-35
Identity = 80/208 (38.46%), Postives = 119/208 (57.21%), Query Frame = 3 
Query:  285 LKSIKVLILHQQNIQKISSLEYCCNLVYLNLSKNFISDFSALKLCQNLNCLDLSSNLIESLPDFNFWNKISTLKFLYLHDNPIANPDSIMGLCSCPSITLLTLWDSPLALRYKYRHFVVNSVWSLKVLDNHFVSDEEIIEDANFKNSLFRSMSEKLQVNSYQTYNNHDGGAVEIDLK---NFLVRINHLISHLSPVLIIQRWIRGYLI 899
            L  I ++ L+   ++ +  +  C  L    L+ NF++    L  C +L  +DL  N I  LPD + W+ +  L+ LYLHDN ++  D+I GL  C  +T LTL+D+P++L+  YRH +VN++WSLK LDN  +SDEEIIE+       FR  ++K Q    + Y      + E ++K     +  IN + +  SP LIIQRWIRGYLI
Sbjct:   33 LTDIVMVRLNSLLVKSLDQIGSCKTLRICILADNFLTRIEPLMECTSLVKIDLKGNQIVQLPDASGWSHLKELQLLYLHDNNMSTWDNIKGLSGCLKLTALTLYDTPVSLKGNYRHRLVNNIWSLKALDNFVISDEEIIENMCLP---FRFKAKK-QHFCVRLYPPTKSDSFETEMKVMYKIITEINRIQAFYSPTLIIQRWIRGYLI 236
[Close]
BLAST of Protein FAM151A vs. Ensembl Zebrafish
Match: lrriq3 (leucine-rich repeats and IQ motif containing 3 [Source:ZFIN;Acc:ZDB-GENE-081104-400])

HSP 1 Score: 105.916 bits (263), Expect = 1.059e-25
Identity = 58/152 (38.16%), Postives = 90/152 (59.21%), Query Frame = 3 
Query:  285 LKSIKVLILHQQNIQKISSLEYCCNLVYLNLSKNFISDFSALKLCQNLNCLDLSSNLIESLPDFNFWNKISTLKFLYLHDNPIANPDSIMGLCSCPSITLLTLWDSPLALRYKYRHFVVNSVWSLKVLDNHFVSDEEIIEDANFKNSLFRSM 740
            L  I ++ L+   ++ +  +  C  L    L+ NF++    L  C +L  +DL  N I  LPD + W+ +  L+ LYLHDN ++  D+I GL  C  +T LTL+D+P++L+  YRH +VN++WSLK LDN  +SDEEIIE+       F+ +
Sbjct:   32 LTDIVMVRLNSLLVKSLDQIGSCKTLRICILADNFLTRIEPLMECTSLVKIDLKGNQIVQLPDASGWSHLKELQLLYLHDNNMSTWDNIKGLSGCLKLTALTLYDTPVSLKGNYRHRLVNNIWSLKALDNFVISDEEIIENMCLPFRGFKPL 183
[Close]
BLAST of Protein FAM151A vs. Ensembl Zebrafish
Match: lrrc9 (leucine rich repeat containing 9 [Source:ZFIN;Acc:ZDB-GENE-080917-56])

HSP 1 Score: 49.6766 bits (117), Expect = 5.228e-6
Identity = 46/146 (31.51%), Postives = 73/146 (50.00%), Query Frame = 3 
Query:  303 LILHQQNIQKISSLEYCCNLVYLNLSKNFISDFSALKLCQNLNCLDLSSNLIESL-----PDFNFWNKISTLKFLYLHDNPIANPDSIMGLCSCPSITLLTLWD-----SPLALRYKYRHFVVNSVWSLKVLDNHFVSDEEIIEDA 710
            L L+  NI +I++LE   NL  L L+KN ISD   L    NL  ++L+ N IE+L     P+ N  N       L L  N I++   +  L   P +  L+L D     +P+ L Y Y   V+  + +L++LD + +S  ++ + A
Sbjct:  106 LFLYDNNIHQITNLEMLVNLCVLWLNKNQISDIQGLDSLVNLEEMNLADNAIETLGHSLDPNCNLQN-------LNLSGNKISSFKELTHLARLPRLRYLSLKDPQCIPNPVCLLYNYYIHVLYHMPNLQLLDTYDMSSRQLKDTA 244
[Close]
BLAST of Protein FAM151A vs. Ensembl Xenopus
Match: chrna7 (cholinergic receptor, nicotinic alpha 7 [Source:Xenbase;Acc:XB-GENE-990456])

HSP 1 Score: 130.568 bits (327), Expect = 4.333e-34
Identity = 69/167 (41.32%), Postives = 109/167 (65.27%), Query Frame = 3 
Query:  261 DDCESFDLLKSIKVLILHQQNIQKISSLEYCCNLVYLNLSKNFISDFSALKLCQNLNCLDLSSNLIESLPDFNFWNKISTLKFLYLHDNPIANPDSIMGLCSCPSITLLTLWDSPLALRYKYRHFVVNSVWSLKVLDNHFVSDEEIIEDANFKNSLFRSMSEKLQVN 761
            ++C + +L   + +L  ++Q +++I+ ++YC +L    LS N+I++  AL+ C ++  LDL  N I+SLPD  FW+ I  LK LYLHDN I +  ++  L +CP++  LTL+D+PL+L   YRH VVNS+WSL  LD + +SDEEI+ED +     F+++S    VN
Sbjct:   22 NNCPAMEL-NEVALLHANKQLLKEINIIQYCISLKICILSNNYITNIDALRRCCHIIKLDLHGNQIKSLPDQGFWSNIKGLKVLYLHDNQIGSLKTVEKLSACPNLKGLTLYDTPLSLHKHYRHTVVNSIWSLNALDEYAISDEEIVEDWSLPGR-FKALSPHFYVN 186
[Close]
BLAST of Protein FAM151A vs. Ensembl Xenopus
Match: CNTRL (centriolin [Source:NCBI gene;Acc:100270771])

HSP 1 Score: 60.4622 bits (145), Expect = 1.030e-8
Identity = 55/174 (31.61%), Postives = 86/174 (49.43%), Query Frame = 3 
Query:  183 ENEGYFTRLSLDYLINNC-SKDNKDEKDDCESFDLLKSIKVLILHQQNIQKISSLEYCCNLVYLNLSKNFISDFSALKLCQNLNCLDLSSNLIESLPDFNFW--NKISTLKFLYLHDNPIANPDSIMGLCSCPSITLLTLWDSPLALRYKYRHFVVNSVWSLKVLDNHFVSDEE 695
            EN  Y T L+L      C +K+   +    E+ +  + ++VL L    I+KI  LE    L  LNL+ N IS     +  QNL  L+L+ N IE +P    W   K+ +L  L L +N I++   +  L     +T L+L D+P++    YR + V  + SL  LD   V+++E
Sbjct:   26 ENLAYVTSLNL------CLAKEGGKKFKFIENLEKCERLEVLNLSHNLIEKIEKLEKQIRLRELNLAYNKISKIEHFEHMQNLKKLNLAGNEIEHIP---VWVGKKLKSLTALNLKENRISSLQDVSRLKPLKDLTTLSLSDNPVSNLPHYRLYTVFHLRSLNSLDAQPVTNQE 190
[Close]
BLAST of Protein FAM151A vs. Ensembl Xenopus
Match: CNTRL (centriolin [Source:NCBI gene;Acc:100270771])

HSP 1 Score: 60.4622 bits (145), Expect = 1.038e-8
Identity = 54/173 (31.21%), Postives = 85/173 (49.13%), Query Frame = 3 
Query:  183 ENEGYFTRLSLDYLINNCSKDNKDEKDDCESFDLLKSIKVLILHQQNIQKISSLEYCCNLVYLNLSKNFISDFSALKLCQNLNCLDLSSNLIESLPDFNFW--NKISTLKFLYLHDNPIANPDSIMGLCSCPSITLLTLWDSPLALRYKYRHFVVNSVWSLKVLDNHFVSDEE 695
            EN  Y T L+L       +K+   +    E+ +  + ++VL L    I+KI  LE    L  LNL+ N IS     +  QNL  L+L+ N IE +P    W   K+ +L  L L +N I++   +  L     +T L+L D+P++    YR + V  + SL  LD   V+++E
Sbjct:   64 ENLAYVTSLNL-----CLAKEGGKKFKFIENLEKCERLEVLNLSHNLIEKIEKLEKQIRLRELNLAYNKISKIEHFEHMQNLKKLNLAGNEIEHIP---VWVGKKLKSLTALNLKENRISSLQDVSRLKPLKDLTTLSLSDNPVSNLPHYRLYTVFHLRSLNSLDAQPVTNQE 228
[Close]
BLAST of Protein FAM151A vs. Ensembl Xenopus
Match: CNTRL (centriolin [Source:NCBI gene;Acc:100270771])

HSP 1 Score: 60.4622 bits (145), Expect = 1.042e-8
Identity = 55/174 (31.61%), Postives = 86/174 (49.43%), Query Frame = 3 
Query:  183 ENEGYFTRLSLDYLINNC-SKDNKDEKDDCESFDLLKSIKVLILHQQNIQKISSLEYCCNLVYLNLSKNFISDFSALKLCQNLNCLDLSSNLIESLPDFNFW--NKISTLKFLYLHDNPIANPDSIMGLCSCPSITLLTLWDSPLALRYKYRHFVVNSVWSLKVLDNHFVSDEE 695
            EN  Y T L+L      C +K+   +    E+ +  + ++VL L    I+KI  LE    L  LNL+ N IS     +  QNL  L+L+ N IE +P    W   K+ +L  L L +N I++   +  L     +T L+L D+P++    YR + V  + SL  LD   V+++E
Sbjct:   53 ENLAYVTSLNL------CLAKEGGKKFKFIENLEKCERLEVLNLSHNLIEKIEKLEKQIRLRELNLAYNKISKIEHFEHMQNLKKLNLAGNEIEHIP---VWVGKKLKSLTALNLKENRISSLQDVSRLKPLKDLTTLSLSDNPVSNLPHYRLYTVFHLRSLNSLDAQPVTNQE 217
[Close]
BLAST of Protein FAM151A vs. Ensembl Xenopus
Match: rbpms2 (RNA binding protein with multiple splicing 2 [Source:Xenbase;Acc:XB-GENE-490341])

HSP 1 Score: 59.6918 bits (143), Expect = 1.700e-8
Identity = 49/156 (31.41%), Postives = 81/156 (51.92%), Query Frame = 3 
Query:  285 LKSIKVLILHQQNIQKISSLEYCCNLVYLNLSKNFISDFSALKLCQNLNCLDLSSNLI---------ESLPDFNFW-NKIS---------TLKFLYLHDNPIANPDSIMGLCSCPSITLLTLWDSPLALRYKYRHFVVNSVWSLKVLDNHFVSDEE 695
            L+S++VL+L +  IQKIS+LE   NL  L+L  N I+    +   + L  L+L+ N I         +SL + N   NKI+         +L+ LYL  N I+  + I+ L    S++ +TL  +P+A    YR  ++  +  L+ LD   +++EE
Sbjct:  231 LRSLRVLMLGKNRIQKISNLENLKNLDVLDLHGNQIAKIENVSHLRELRVLNLARNQINQVENINGLDSLKELNLRDNKITFLRDVDTLPSLQLLYLSFNNISRINDILCLADSTSLSDVTLDGNPIAQESWYRQTILGHMLQLRQLDMKRITEEE 386
[Close]
BLAST of Protein FAM151A vs. Ensembl Mouse
Match: Lrriq3 (leucine-rich repeats and IQ motif containing 3 [Source:MGI Symbol;Acc:MGI:1921685])

HSP 1 Score: 154.451 bits (389), Expect = 1.476e-41
Identity = 82/197 (41.62%), Postives = 123/197 (62.44%), Query Frame = 3 
Query:  321 NIQKISSLEYCCNLVYLNLSKNFISDFSALKLCQNLNCLDLSSNLIESLPDFNFWNKISTLKFLYLHDNPIANPDSIMGLCSCPSITLLTLWDSPLALRYKYRHFVVNSVWSLKVLDNHFVSDEEIIEDANFKNSLFRSMSEKLQVNSYQTYNNHDGGAVEI-DLKNFLVRINHLISHLSPVLIIQRWIRGYLIRKR 908
            +++ + +L+ C +L     S NF++D   L+ C+ L  LDL  N I++LPD NFW+ +  LK LYLHDN  +   +I  L  C S+  LT++D P++L+  YRH +VNS+W LK LD+H +SDEEII++       F++ S  L  N Y           EI ++K+ + RIN +++H SPVLIIQRWIRG+++RK 
Sbjct:   39 HLKSMENLQTCISLRVCIFSNNFLTDIQPLQSCKKLIKLDLHGNQIKTLPDKNFWSGLKNLKLLYLHDNGFSKLKNICVLSGCVSLIGLTMFDCPVSLKKGYRHVLVNSIWPLKALDHHVISDEEIIQNWRLPER-FKTFSPSLFFNLYPALIKGTTYEDEIKNIKHIISRINEILAHNSPVLIIQRWIRGFIVRKH 234
[Close]
BLAST of Protein FAM151A vs. Ensembl Mouse
Match: Lrriq3 (leucine-rich repeats and IQ motif containing 3 [Source:MGI Symbol;Acc:MGI:1921685])

HSP 1 Score: 155.221 bits (391), Expect = 2.867e-41
Identity = 82/197 (41.62%), Postives = 123/197 (62.44%), Query Frame = 3 
Query:  321 NIQKISSLEYCCNLVYLNLSKNFISDFSALKLCQNLNCLDLSSNLIESLPDFNFWNKISTLKFLYLHDNPIANPDSIMGLCSCPSITLLTLWDSPLALRYKYRHFVVNSVWSLKVLDNHFVSDEEIIEDANFKNSLFRSMSEKLQVNSYQTYNNHDGGAVEI-DLKNFLVRINHLISHLSPVLIIQRWIRGYLIRKR 908
            +++ + +L+ C +L     S NF++D   L+ C+ L  LDL  N I++LPD NFW+ +  LK LYLHDN  +   +I  L  C S+  LT++D P++L+  YRH +VNS+W LK LD+H +SDEEII++       F++ S  L  N Y           EI ++K+ + RIN +++H SPVLIIQRWIRG+++RK 
Sbjct:   39 HLKSMENLQTCISLRVCIFSNNFLTDIQPLQSCKKLIKLDLHGNQIKTLPDKNFWSGLKNLKLLYLHDNGFSKLKNICVLSGCVSLIGLTMFDCPVSLKKGYRHVLVNSIWPLKALDHHVISDEEIIQNWRLPER-FKTFSPSLFFNLYPALIKGTTYEDEIKNIKHIISRINEILAHNSPVLIIQRWIRGFIVRKH 234
[Close]
BLAST of Protein FAM151A vs. Ensembl Mouse
Match: Lrriq3 (leucine-rich repeats and IQ motif containing 3 [Source:MGI Symbol;Acc:MGI:1921685])

HSP 1 Score: 158.688 bits (400), Expect = 2.038e-40
Identity = 82/196 (41.84%), Postives = 123/196 (62.76%), Query Frame = 3 
Query:  321 NIQKISSLEYCCNLVYLNLSKNFISDFSALKLCQNLNCLDLSSNLIESLPDFNFWNKISTLKFLYLHDNPIANPDSIMGLCSCPSITLLTLWDSPLALRYKYRHFVVNSVWSLKVLDNHFVSDEEIIEDANFKNSLFRSMSEKLQVNSYQTYNNHDGGAVEI-DLKNFLVRINHLISHLSPVLIIQRWIRGYLIRK 905
            +++ + +L+ C +L     S NF++D   L+ C+ L  LDL  N I++LPD NFW+ +  LK LYLHDN  +   +I  L  C S+  LT++D P++L+  YRH +VNS+W LK LD+H +SDEEII++       F++ S  L  N Y           EI ++K+ + RIN +++H SPVLIIQRWIRG+++RK
Sbjct:   39 HLKSMENLQTCISLRVCIFSNNFLTDIQPLQSCKKLIKLDLHGNQIKTLPDKNFWSGLKNLKLLYLHDNGFSKLKNICVLSGCVSLIGLTMFDCPVSLKKGYRHVLVNSIWPLKALDHHVISDEEIIQNWRLPER-FKTFSPSLFFNLYPALIKGTTYEDEIKNIKHIISRINEILAHNSPVLIIQRWIRGFIVRK 233
[Close]
BLAST of Protein FAM151A vs. Ensembl Mouse
Match: Nisch (nischarin [Source:MGI Symbol;Acc:MGI:1928323])

HSP 1 Score: 57.3806 bits (137), Expect = 8.174e-8
Identity = 39/126 (30.95%), Postives = 68/126 (53.97%), Query Frame = 3 
Query:  270 ESFDLLKSIKVLILHQQNIQKISSLEYCCNLVYLNLSKNFISDFSALKL-CQNLNCLDLSSNLIESLPDFNFWNKISTLKFLYLHDNPIANPDSIMGLCSCPSITLLTLWDSPLALRYKYRHFVVN 644
            ES  L+  I+ L L    ++ + +L++  NLV+L+LS N +S    +     N+  L+L+ N +ESL   +   K+ +L  + L DN I   D +  + S P +  LTL ++PL++   YR  V++
Sbjct:  306 ESVKLIPKIEYLDLSHNGLRVVDNLQHLYNLVHLDLSYNKLSSLEGVHTKLGNVKTLNLAGNFLESLSGLH---KLYSLVNVDLRDNRIEQLDEVKSIGSLPCLERLTLLNNPLSIIPDYRTKVLS 428
[Close]
BLAST of Protein FAM151A vs. Ensembl Mouse
Match: Nisch (nischarin [Source:MGI Symbol;Acc:MGI:1928323])

HSP 1 Score: 56.9954 bits (136), Expect = 9.169e-8
Identity = 39/126 (30.95%), Postives = 68/126 (53.97%), Query Frame = 3 
Query:  270 ESFDLLKSIKVLILHQQNIQKISSLEYCCNLVYLNLSKNFISDFSALKL-CQNLNCLDLSSNLIESLPDFNFWNKISTLKFLYLHDNPIANPDSIMGLCSCPSITLLTLWDSPLALRYKYRHFVVN 644
            ES  L+  I+ L L    ++ + +L++  NLV+L+LS N +S    +     N+  L+L+ N +ESL   +   K+ +L  + L DN I   D +  + S P +  LTL ++PL++   YR  V++
Sbjct:   61 ESVKLIPKIEYLDLSHNGLRVVDNLQHLYNLVHLDLSYNKLSSLEGVHTKLGNVKTLNLAGNFLESLSGLH---KLYSLVNVDLRDNRIEQLDEVKSIGSLPCLERLTLLNNPLSIIPDYRTKVLS 183
[Close]
BLAST of Protein FAM151A vs. UniProt/SwissProt
Match: sp|Q6AYL8|LRIQ3_RAT (Leucine-rich repeat and IQ domain-containing protein 3 OS=Rattus norvegicus OX=10116 GN=Lrriq3 PE=2 SV=1)

HSP 1 Score: 160.229 bits (404), Expect = 4.252e-40
Identity = 81/196 (41.33%), Postives = 123/196 (62.76%), Query Frame = 3 
Query:  321 NIQKISSLEYCCNLVYLNLSKNFISDFSALKLCQNLNCLDLSSNLIESLPDFNFWNKISTLKFLYLHDNPIANPDSIMGLCSCPSITLLTLWDSPLALRYKYRHFVVNSVWSLKVLDNHFVSDEEIIEDANFKNSLFRSMSEKLQVNSYQTYNNHDGGAVEI-DLKNFLVRINHLISHLSPVLIIQRWIRGYLIRK 905
            +++ + +L+ C +L     S NF++D   L+ C+ L  LDL  N I++LPD  FWN +  LK LYLHDN  A   +I  L  C ++  LT++D P++L+  YRH +VNS+W LK LD+H +SDEEII++ +     F++ S+ L  N             EI ++K+ + RIN +++H SPVLIIQRWIRG+++RK
Sbjct:   39 HLKSMENLQSCISLRVCIFSNNFVTDIQPLQGCKKLIKLDLHGNQIKTLPDRTFWNGLKNLKLLYLHDNGFAKLKNICVLSGCVNLVGLTMFDCPVSLKKGYRHVLVNSIWPLKALDHHVISDEEIIQNWHLPER-FKTFSQSLFFNICPAPIKGTTYEDEIKNIKHIISRINEILAHNSPVLIIQRWIRGFIVRK 233
[Close]
BLAST of Protein FAM151A vs. UniProt/SwissProt
Match: sp|Q14DL3|LRIQ3_MOUSE (Leucine-rich repeat and IQ domain-containing protein 3 OS=Mus musculus OX=10090 GN=Lrriq3 PE=2 SV=1)

HSP 1 Score: 158.688 bits (400), Expect = 1.426e-39
Identity = 82/196 (41.84%), Postives = 123/196 (62.76%), Query Frame = 3 
Query:  321 NIQKISSLEYCCNLVYLNLSKNFISDFSALKLCQNLNCLDLSSNLIESLPDFNFWNKISTLKFLYLHDNPIANPDSIMGLCSCPSITLLTLWDSPLALRYKYRHFVVNSVWSLKVLDNHFVSDEEIIEDANFKNSLFRSMSEKLQVNSYQTYNNHDGGAVEI-DLKNFLVRINHLISHLSPVLIIQRWIRGYLIRK 905
            +++ + +L+ C +L     S NF++D   L+ C+ L  LDL  N I++LPD NFW+ +  LK LYLHDN  +   +I  L  C S+  LT++D P++L+  YRH +VNS+W LK LD+H +SDEEII++       F++ S  L  N Y           EI ++K+ + RIN +++H SPVLIIQRWIRG+++RK
Sbjct:   39 HLKSMENLQTCISLRVCIFSNNFLTDIQPLQSCKKLIKLDLHGNQIKTLPDKNFWSGLKNLKLLYLHDNGFSKLKNICVLSGCVSLIGLTMFDCPVSLKKGYRHVLVNSIWPLKALDHHVISDEEIIQNWRLPER-FKTFSPSLFFNLYPALIKGTTYEDEIKNIKHIISRINEILAHNSPVLIIQRWIRGFIVRK 233
[Close]
BLAST of Protein FAM151A vs. UniProt/SwissProt
Match: sp|A6PVS8|LRIQ3_HUMAN (Leucine-rich repeat and IQ domain-containing protein 3 OS=Homo sapiens OX=9606 GN=LRRIQ3 PE=1 SV=1)

HSP 1 Score: 157.532 bits (397), Expect = 3.111e-39
Identity = 81/196 (41.33%), Postives = 123/196 (62.76%), Query Frame = 3 
Query:  321 NIQKISSLEYCCNLVYLNLSKNFISDFSALKLCQNLNCLDLSSNLIESLPDFNFWNKISTLKFLYLHDNPIANPDSIMGLCSCPSITLLTLWDSPLALRYKYRHFVVNSVWSLKVLDNHFVSDEEIIEDANFKNSLFRSMSEKLQVNSYQTYNNHDGGAVEI-DLKNFLVRINHLISHLSPVLIIQRWIRGYLIRK 905
            +++ + +L+ C +L     S NFI+D   L+ C  L  LDL  N I+SLP+  FWN +  LK LYLHDN  A   +I  L +CP++  LT++D P++L+  YRH +VNS+W LK LD+H +SDEEII++ +     F++ + +L  N             EI ++K+   +IN +++H SPVLI+QRWIRG+L+RK
Sbjct:   39 HLKSMENLQSCISLRVCIFSNNFITDIHPLQSCIKLIKLDLHGNQIKSLPNTKFWNGLKNLKLLYLHDNGFAKLKNICVLSACPTLIALTMFDCPVSLKKGYRHVLVNSIWPLKALDHHVISDEEIIQNWHLPER-FKACNHRLFFNFCPALRKGTTYEEEINNIKHITSKINAILAHNSPVLIVQRWIRGFLVRK 233
[Close]
BLAST of Protein FAM151A vs. UniProt/SwissProt
Match: sp|Q8IUZ0|LRC49_HUMAN (Leucine-rich repeat-containing protein 49 OS=Homo sapiens OX=9606 GN=LRRC49 PE=2 SV=2)

HSP 1 Score: 66.2402 bits (160), Expect = 7.826e-10
Identity = 45/137 (32.85%), Postives = 75/137 (54.74%), Query Frame = 3 
Query:  285 LKSIKVLILHQQNIQKISSLEYCCNLVYLNLSKNFISDFSALKLCQNLNCLDLSSNLIESLPDFNFWNKISTLKFLYLHDNPIANPDSIMGLCSCPSITLLTLWDSPLALRYKYRHFVVNSVWSLKVLDNHFVSDEE 695
            LKS+ VL LH   I KI ++ + C L  LNL++NF+S    L    +L  L+L  N I  + D    + +  L+ L+L  N I++ DS+  L    S++ +T   +P+A    Y+H V+ ++  L+ LD   +++EE
Sbjct:  177 LKSLDVLDLHGNQITKIENINHLCELRVLNLARNFLSHVDNLNGLDSLTELNLRHNQITFVRDV---DNLPCLQHLFLSFNNISSFDSVSCLADSSSLSDITFDGNPIAQESWYKHTVLQNMMQLRQLDMKRITEEE 310
[Close]
BLAST of Protein FAM151A vs. UniProt/SwissProt
Match: sp|Q80TM9|NISCH_MOUSE (Nischarin OS=Mus musculus OX=10090 GN=Nisch PE=1 SV=2)

HSP 1 Score: 57.3806 bits (137), Expect = 5.718e-7
Identity = 39/126 (30.95%), Postives = 68/126 (53.97%), Query Frame = 3 
Query:  270 ESFDLLKSIKVLILHQQNIQKISSLEYCCNLVYLNLSKNFISDFSALKL-CQNLNCLDLSSNLIESLPDFNFWNKISTLKFLYLHDNPIANPDSIMGLCSCPSITLLTLWDSPLALRYKYRHFVVN 644
            ES  L+  I+ L L    ++ + +L++  NLV+L+LS N +S    +     N+  L+L+ N +ESL   +   K+ +L  + L DN I   D +  + S P +  LTL ++PL++   YR  V++
Sbjct:  306 ESVKLIPKIEYLDLSHNGLRVVDNLQHLYNLVHLDLSYNKLSSLEGVHTKLGNVKTLNLAGNFLESLSGLH---KLYSLVNVDLRDNRIEQLDEVKSIGSLPCLERLTLLNNPLSIIPDYRTKVLS 428
[Close]
BLAST of Protein FAM151A vs. TrEMBL
Match: A0A2C9LCG7 (Uncharacterized protein OS=Biomphalaria glabrata OX=6526 GN=106051317 PE=4 SV=1)

HSP 1 Score: 207.994 bits (528), Expect = 1.010e-53
Identity = 197/732 (26.91%), Postives = 348/732 (47.54%), Query Frame = 3 
Query:   63 MVSIPS----SQIKNIIYFDISAQKLSNKITK-PQTNIRLAIKNAENEGYFTRLSLDYLINNCSKDNKDEKDDCESFDLLKSIKVLILHQQNIQKISSLEYCC-NLVYLNLSKNFISDFSALKLCQNLNCLDLSSNLIESLPDFNFWNKISTLKFLYLHDNPIANPDSIMGLCSCPSITLLTLWDSPLALRYKYRHFVVNSVWSLKVLDNHFVSDEEIIEDANFKNSLFRSMSEKLQVN-SYQTYNNHDGGAVEIDLKNFLVRINHLISHLSPVLIIQRWIRGYLIRKRYEXXXXXXXXXXXXXPQIARSPIAAVKENSEHQENVKYLKIDLLHLNKNSTLENIDKEASIRSLITSTL-NMLTYRSFIKQDQDKCSPEHISRALKSDTFTVDD----------PGNCY----------------------------------NLD-----EKI---SFKFRGSKPPISTKTIATEVKNEKSRSHYFIREADRNYHDQILTQLPVIKSKPLKKINSSILFRKAQDCMSLFLLNKWDKADRDIQDVQRFHEKMATVRMIKVDREVNQMKLEDAKLNKLALIRQQHKDLKSVVERSLETDKKNNKIAG-ELVKM--------KKMEATDRRMKMMQEMGFSQDFRSKQTAASKAVDKFEQTTYKQEQLESNKVAVDETRQKMKVEKETVKAYLENQAINRRTERTLENSALDVQILQQTNSRINDAKMRVEKLKA 2051
            MVSIP     +Q+ +    D  +Q L NK  K  +T +   +K+A   GY    + + L ++C   N +E +D   F L   I +  +H +N+  I    +CC NL    LS N+++   +L  C++L  LDL SN + ++P  NFW+ +  L+ LYLHDNP+   + +  L SC  +TLLTL+D+PLAL+  YRH VVNS+W+LK LD+  +SDEEIIEDA F N  F+++S   ++     TY N         +K  ++ +N +++  SPVLI+QR IRG+L+RKR  +  ++         ++   P   +    + + ++  + ID     KN    ++  E + R++ +  + +M++ +S I  + DK   + +S +L++DT  ++           P N +                                  +LD     E I   SF+ +G           TE+   K  S   +REA+     +   +      +P    N    F +AQ  M L  L    KA  + +  ++   K+  +  ++ +R  +Q        +++ + R+Q + L+ +  R LE      +I   EL K+        +K+ ++D   +      F  DF S+ T+ SKA+ + ++    ++   + +  V   +     +++ VK Y+E++ + R+TE ++  +AL  ++L + N R+ DA+ RV +LKA
Sbjct:    1 MVSIPDWARFAQLIDTKQQD--SQNLLNKFYKQKETEV---MKHALESGYIFVATKEALSSHCIDQNPEE-NDVTKFRL---ISLAGIHIRNLGDI----WCCSNLTICLLSNNYLTKIDSLAHCKHLIKLDLHSNQLITVPGLNFWSHLRNLQILYLHDNPLGKFEILKNLSSCSYLTLLTLYDTPLALKKNYRHHVVNSIWTLKALDHFVISDEEIIEDAVF-NGRFQALSPPFRIILCPPTYANPTYSTELEGIKGIMMEVNRILAKHSPVLIVQRCIRGFLVRKRLHRLHALGGLKLK---EVFPPPGTPIYLKDQVKTSLLGVNIDYDTYMKNRRPGSLVPEETFRTMQSEEMPSMVSNKSLIVINMDKLEEDMLS-SLQADTVAMEKLLADKKKIGLPHNSFQESSIKKAKKSDTKSKFSRIKNQKHFFGPVVFNDSLDDSEDEESIPFNSFRLKGQTEKCIIADATTEMILNKKESGKMVREAETERMTKAFFETKPKVERPNFLTNEQRFFNRAQGTMGLSCLMAVQKAYNEREKAEKAAAKIENILGLREERLRSQ--------DRVNMYREQRR-LQVLKARDLERSLIMEQIEKHELEKINFLDKQQERKVRSSDVNKQSRSNQTFVVDFNSQHTSVSKALLRHDRQARWEDSHSNRRNQVTNAKLTELEQQDVVKNYMEHRQLMRQTETSVAKAALGTKMLAEANERMMDARNRVAQLKA 705
[Close]
BLAST of Protein FAM151A vs. TrEMBL
Match: C3Y2J8 (Uncharacterized protein OS=Branchiostoma floridae OX=7739 GN=BRAFLDRAFT_124759 PE=4 SV=1)

HSP 1 Score: 198.749 bits (504), Expect = 5.208e-50
Identity = 103/251 (41.04%), Postives = 150/251 (59.76%), Query Frame = 3 
Query:  171 IKNAENEGYFTRLSLDYLINNCSKDNKDEK--DDCESFDLLKSIKVLILHQQNIQKISSLEYCCNLVYLNLSKNFISDFSALKLCQNLNCLDLSSNLIESLPDFNFWNKISTLKFLYLHDNPIANPDSIMGLCSCPSITLLTLWDSPLALRYKYRHFVVNSVWSLKVLDNHFVSDEEIIEDANFKNSLFRSMSEKLQVNSYQTYNNHDGGAVEIDLK---NFLVRINHLISHLSPVLIIQRWIRGYLIRKR 908
            I+ AE  GY    S  +++  C   ++D++  D  + +D    I+++ + Q +++ I  ++ C  L    LS N+I+ F AL  C  L  LDL SN +  LP   FW  +  LK L+LHDNPI   D +  L SCPS+  LT++D+PL+LR  YRH VVN++WSLKVLDN+ +SDEEIIED+NF    F ++   L +N     N      +E +L+   + L  IN L++H SPVL+IQRW+RG+L R R
Sbjct:   34 IRTAEERGYLLSPSKSFVLEQCLGKSQDKRREDPQKIYD----IQIVHMTQAHLRNIGYIQSCTRLQVCILSNNYITRFDALAACTMLVKLDLHSNQVSVLPSAQFWEGMERLKALFLHDNPIGRLDCLHNLGSCPSLVALTMYDTPLSLRASYRHHVVNTIWSLKVLDNYLISDEEIIEDSNF-GGRFSTLHPSLFIN--MGPNTRRDATLEEELEDVDDLLQAINVLLAHCSPVLVIQRWVRGHLGRLR 277

HSP 2 Score: 79.7221 bits (195), Expect = 1.497e-11
Identity = 73/270 (27.04%), Postives = 131/270 (48.52%), Query Frame = 3 
Query: 1245 KISFKFRGSKPPISTKTIATEVKNEKSRSHYFIREADRNYHDQILTQLPVIKSKPLKKIN-SSILFRKAQDCMSLFLLNKWDKADRDIQDVQRFHEKMATVRMIKVDREVNQMKLEDAKLNKLA-LIRQQHKDLKSVVERSLETDKKNNKIAGELVKMKKMEATDRRMKMMQEMGFSQDFRSKQTAASKAVDKFEQTTYKQEQLESNKVAVDETRQKMKVEKETVKAYLENQAINRRTERTLENSALDVQILQQTNSRINDAKMRVEKLK 2048
            ++ F+  G KP +       E+   K      +R A+R  H + L   P  K  P + +     LF KAQ  M +       +A +D +   +  EKM  V  +K  RE  + +++     K    +R++ KD   V E +LE  +  +    E     + +A +R      ++ F  DF S+ T+ S A+ + ++ T K++     K    +TR++ + +KE V+ YLE++ + R+ E + E S LD ++LQ  N+R+ +A++RV +LK
Sbjct:  491 QVQFRLSGLKPVLHAADAVQEMLIAKREGAEDVRSAER-VHREYLASQPQPKLPPKQVVTLDQRLFSKAQGTMGMTCFKAVQQAYKDRKRAAQIAEKMDQVMAVKDQREQAKNRVQGFMHQKRNNALRRREKDGVEVSE-ALEKHELKHINYIEKRYETRGKAFERTKARFADLAFMADFSSQHTSVSNALLRHDRQTRKEDDSSERKDKYRQTREQSQEQKELVRRYLEHRQLMRQAEVSTERSVLDSKMLQDANNRLMEARVRVAQLK 758
[Close]
BLAST of Protein FAM151A vs. TrEMBL
Match: A0A210R137 (Leucine-rich repeat and IQ domain-containing protein 3 OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT04204 PE=4 SV=1)

HSP 1 Score: 190.66 bits (483), Expect = 2.216e-47
Identity = 102/249 (40.96%), Postives = 146/249 (58.63%), Query Frame = 3 
Query:  168 AIKNAENEGYFTRLSLDYLINNCSKDNKDEKDDCESFDLLKSIKVLILHQQNIQKISSLEYCCNLVYLNLSKNFISDFSALKLCQNLNCLDLSSNLIESLPDFNFWNKISTLKFLYLHDNPIANPDSIMGLCSCPSITLLTLWDSPLALRYKYRHFVVNSVWSLKVLDNHFVSDEEIIEDANFKNSLFRSMSEKLQVN-SYQTYNNHDGGAVEIDLKNFLVRINHLISHLSPVLIIQRWIRGYLIRKRY 911
            AI+ AE  GYF   +  YL+      N  +  D     L+K + V      +++KI  + YC NL    LS NF++    L  C+ L  LDL SN I S+P   FW+ +  L+ L+LHDNP+   +++  L +CPS+ +LTL+D+PL+L+  YRH VVNSVWSLK LD+H +SDEEIIEDA F    F ++    +++    T  + D       +      INH+++H SPVLIIQR++RG+L RKRY
Sbjct:   36 AIRQAEERGYFRVPTQTYLLEENDFRNGRKVRDLSQLQLVKLVGV------HLRKIGDIAYCVNLRICVLSNNFLTKIDDLTSCRQLVKLDLHSNQISSIPGVAFWSGMRKLRILHLHDNPLGKYETLQNLATCPSLIVLTLYDTPLSLKRNYRHHVVNSVWSLKALDHHVISDEEIIEDAIFGGK-FGTLHPAFRIDLCPPTLEDSDYQEELYTIYLVEAYINHIMAHHSPVLIIQRFMRGHLARKRY 277
[Close]
BLAST of Protein FAM151A vs. TrEMBL
Match: A0A2T7NKM4 (Uncharacterized protein OS=Pomacea canaliculata OX=400727 GN=C0Q70_17506 PE=4 SV=1)

HSP 1 Score: 182.956 bits (463), Expect = 6.385e-45
Identity = 96/250 (38.40%), Postives = 151/250 (60.40%), Query Frame = 3 
Query:  162 RLAIKNAENEGYFTRLSLDYLINNCSKDNKDEKDDCESFDLLKSIKVLILHQQNIQKISSLEYCCNLVYLNLSKNFISDFSALKLCQNLNCLDLSSNLIESLPDFNFWNKISTLKFLYLHDNPIANPDSIMGLCSCPSITLLTLWDSPLALRYKYRHFVVNSVWSLKVLDNHFVSDEEIIEDANFKNSLFRSMSEKLQVNSYQTYNNHDGGAVEID-LKNFLVRINHLISHLSPVLIIQRWIRGYLIRKR 908
            ++A++ AE +GYF   S DY++      N   K        +K I ++ L   ++QK+  +  C NL    L+ NF+++  AL  C +L  LDL  N + S+PD  FW+ +  L+ LYLHDNP+ N +++  L  C  +T+LTL+D+PL LR  YRH+VVNS+W+LK LD+H +SDEEIIEDA F+   F ++    +++ +   +N+     E+  L+     IN +++  SPV+IIQR+ RGY+ RK+
Sbjct:   35 QVALREAEEQGYFLVPSCDYILKYIGPCNAMSKS-------IKQIFLVKLDGVHMQKLGDISLCTNLKICILANNFLTNVDALARCYHLVKLDLHGNQMSSIPDPIFWSGLKKLRALYLHDNPLGNLETLQNLTVCRCLTILTLYDTPLYLRKNYRHYVVNSIWTLKALDHHVISDEEIIEDAFFRGH-FSALCPPFRLDLWLASSNNTTYQEELKLLQKLEACINRILARNSPVIIIQRYFRGYITRKK 276

HSP 2 Score: 62.7734 bits (151), Expect = 2.925e-6
Identity = 53/218 (24.31%), Postives = 106/218 (48.62%), Query Frame = 3 
Query: 1422 NSSILFRKAQDCMSLFLLNKWDKADRDIQDVQRFHEKMATVRMIKVDREVNQMKLE-DAKLNKLALIRQQHKDLKSVVER-------SLETDKKNNKIAGELVKMKKMEATDRRMKMMQEMGFSQDFRSKQTAASKAVDKFEQTTYKQEQLESNKVAVDETRQKMKVEKETVKAYLENQAINRRTERTLENSALDVQILQQTNSRINDAKMRVEKLKA 2051
            N   LF +    MSL  L    KA +D ++ ++   K   V++++ +R+  +  ++   +  ++ L+ +Q  D  S++++        L    + ++  G    M +    ++         F  +F S+ T+ S A+ + ++    +++  S +  V   R     ++E VK YLE++ + R+TE +L  +ALD  ILQ+T  R+ +AK RV  +KA
Sbjct:  499 NKQRLFARVYGTMSLSCLLAVQKAYQDRENAEKLTAKKEHVKILRDERQRAKESIQFYLQQKRIRLMHKQDLDQASLLDQLEKKELQQLNYLDRQHEAKGWATAMTRSHYANK--------TFMTEFNSQHTSVSNALLRHDRQAKNEDKNSSQRAKVQNLRSDKHEQQEMVKKYLEHRQLMRQTEASLARTALDSHILQETTDRLMEAKQRVAHIKA 708
[Close]
BLAST of Protein FAM151A vs. TrEMBL
Match: H2YJZ8 (Uncharacterized protein OS=Ciona savignyi OX=51511 PE=4 SV=1)

HSP 1 Score: 171.785 bits (434), Expect = 1.246e-44
Identity = 103/279 (36.92%), Postives = 156/279 (55.91%), Query Frame = 3 
Query:   90 KNIIYFDISAQKLSNKITKPQTNIRLA---IKNAENEGYFTRLSLDYLINNCSKDNKDEKDDCESFDLLKSIKVLILHQQNIQKISSLEYCCNLVYLNLSKNFISDFSALKLCQNLNCLDLSSNLIESLPDFNFWNKISTLKFLYLHDNPIANPDSIMGLCSCPSITLLTLWDSPLALRYKYRHFVVNSVWSLKVLDNHFVSDEEIIEDANFKNSLFRSMSEKLQVN----SYQTYNNHDGGAVEIDLKNFLVRINHLISHLSPVLIIQRWIRGYLIRK 905
            +NI+    + Q+ + K T  +   RLA   ++ A   GY    S  +L+  C    K           LK I+ + L   +I+ +  ++ C +L    L+ N+++ FSAL+ C  L  LDL SN I  LPD NFW ++ +L+ L LHDN I   + I  LC C ++ +LTL+D+PL+L+  YRH  VNS+WSLK LD+H + DEEIIED+ F    F +M+ KL V+      +  N+    +    ++  L  IN ++ H SPV++IQRW+RG+L RK
Sbjct:   10 QNILQVRQNLQRKTKKTTPSKWENRLADAALRQAAEGGYLISPSRAFLLERCQTAGKPS---------LKDIEYIHLSHFHIRTLGHIQSCRHLRVCILNNNYLTRFSALENCPYLVRLDLHSNQITKLPDENFWREMKSLRILNLHDNGIGKLEDIQSLCVCVNLVVLTLYDTPLSLKANYRHHTVNSIWSLKALDHHVIGDEEIIEDSLFSKR-FTAMNPKLFVDLCPKQNEALNDRTLQSEMKTVRKILSDINRILVHGSPVVVIQRWVRGHLSRK 278
[Close]
BLAST of Protein FAM151A vs. Ensembl Cavefish
Match: lrriq3 (leucine-rich repeats and IQ motif containing 3 [Source:ZFIN;Acc:ZDB-GENE-081104-400])

HSP 1 Score: 141.739 bits (356), Expect = 8.229e-38
Identity = 81/194 (41.75%), Postives = 118/194 (60.82%), Query Frame = 3 
Query:  318 QNIQKISSLEYCCNLVYLNLSKNFISDFSALKLCQNLNCLDLSSNLIESLPDFNFWNKISTLKFLYLHDNPIANPDSIMGLCSCPSITLLTLWDSPLALRYKYRHFVVNSVWSLKVLDNHFVSDEEIIEDANFKNSLFRSMSEKLQVNSYQTYNNHDGGAVEIDL-KNFLVRINHLISHLSPVLIIQRWIRGYL 896
            +N+ +I S   C  L    L+ NF++    L  C +L  LDL  N I  LP  +FW+ +  L+ L LHDN IA+  +I  L  CP +T LTL+D+PL+L+  YRH VVNS+WSLK LD+H +SD+EI+E+       F++M+    VN Y   N  D    E+ +    +V+INH+ ++  P+LIIQ+WIRG+L
Sbjct:   49 KNLDQIGS---CKALKICILANNFLTKIDPLIECVSLVKLDLKGNQITHLPSASFWSNLKDLQLLNLHDNTIADRSNISALSGCPRLTALTLYDTPLSLKRNYRHCVVNSLWSLKALDHHVISDQEIVENWCLHPK-FKTMASPFSVNLYPPLNV-DSYQNELKMVHELIVKINHIQANYCPILIIQKWIRGHL 237
[Close]
BLAST of Protein FAM151A vs. Ensembl Cavefish
Match: ENSAMXT00000021515.2 (leucine rich repeat containing 49 [Source:NCBI gene;Acc:103024138])

HSP 1 Score: 53.5286 bits (127), Expect = 7.531e-7
Identity = 44/141 (31.21%), Postives = 69/141 (48.94%), Query Frame = 3 
Query:  273 SFDLLKSIKVLILHQQNIQKISSLEYCCNLVYLNLSKNFISDFSALKLCQNLNCLDLSSNLIESLPDFNFWNKISTLKFLYLHDNPIANPDSIMGLCSCPSITLLTLWDSPLALRYKYRHFVVNSVWSLKVLDNHFVSDEE 695
              D L  + VL LH   I K+ +L +   L  LNL+ N I     L    +L  L+L  N I S+ + +    +S L+ L+L  N I++ D +  L    S+  LTL  +P+A    Y+   +  V  L++LD   ++DEE
Sbjct:  250 GLDNLTKLDVLDLHNNQISKMENLSHLSELRVLNLAGNCICRVENLHGLDSLTELNLRYNHISSVTEVDL---LSCLQRLFLSSNSISSFDELACLGLSCSLCELTLDGNPVAQESCYKQAALRCVLPLRLLDMKRITDEE 387
[Close]
BLAST of Protein FAM151A vs. Ensembl Cavefish
Match: LRRC9 (leucine-rich repeat-containing protein 9-like [Source:NCBI gene;Acc:103026999])

HSP 1 Score: 52.373 bits (124), Expect = 1.748e-6
Identity = 47/141 (33.33%), Postives = 73/141 (51.77%), Query Frame = 3 
Query:  303 LILHQQNIQKISSLEYCCNLVYLNLSKNFISDFSALKLCQNLNCLDLSSNLIESLPDFNFWNKISTLKFLYLHDNPIANPDSIMGLCSCPSITLLTLWD-----SPLALRYKYRHFVVNSVWSLKVLDNHFVSDEEIIEDA 710
            L L+  NI KISSLE   NL  L L+ N IS+   L +  NL  L+L+ NLIES+   N  ++ + L+ L L  N I++   +  L     +  L L D     +P+ +   Y   ++  V +L+ LD++ V+ + I E A
Sbjct:  106 LFLYDNNISKISSLELLTNLQVLWLNNNIISEIEGLSMLGNLRELNLADNLIESI--GNSLDQNTNLQKLNLSGNKISSFKELTHLTRLSKLRELGLKDPQSRPNPVCMLCNYFTHILYHVPTLQRLDSYDVTSKAIKESA 244
[Close]
BLAST of Protein FAM151A vs. Ensembl Cavefish
Match: LRRC9 (leucine-rich repeat-containing protein 9-like [Source:NCBI gene;Acc:103026999])

HSP 1 Score: 52.373 bits (124), Expect = 1.850e-6
Identity = 47/141 (33.33%), Postives = 73/141 (51.77%), Query Frame = 3 
Query:  303 LILHQQNIQKISSLEYCCNLVYLNLSKNFISDFSALKLCQNLNCLDLSSNLIESLPDFNFWNKISTLKFLYLHDNPIANPDSIMGLCSCPSITLLTLWD-----SPLALRYKYRHFVVNSVWSLKVLDNHFVSDEEIIEDA 710
            L L+  NI KISSLE   NL  L L+ N IS+   L +  NL  L+L+ NLIES+   N  ++ + L+ L L  N I++   +  L     +  L L D     +P+ +   Y   ++  V +L+ LD++ V+ + I E A
Sbjct:  106 LFLYDNNISKISSLELLTNLQVLWLNNNIISEIEGLSMLGNLRELNLADNLIESI--GNSLDQNTNLQKLNLSGNKISSFKELTHLTRLSKLRELGLKDPQSRPNPVCMLCNYFTHILYHVPTLQRLDSYDVTSKAIKESA 244
[Close]
BLAST of Protein FAM151A vs. Ensembl Cavefish
Match: LRRC9 (leucine-rich repeat-containing protein 9-like [Source:NCBI gene;Acc:103026999])

HSP 1 Score: 52.373 bits (124), Expect = 2.061e-6
Identity = 47/141 (33.33%), Postives = 73/141 (51.77%), Query Frame = 3 
Query:  303 LILHQQNIQKISSLEYCCNLVYLNLSKNFISDFSALKLCQNLNCLDLSSNLIESLPDFNFWNKISTLKFLYLHDNPIANPDSIMGLCSCPSITLLTLWD-----SPLALRYKYRHFVVNSVWSLKVLDNHFVSDEEIIEDA 710
            L L+  NI KISSLE   NL  L L+ N IS+   L +  NL  L+L+ NLIES+   N  ++ + L+ L L  N I++   +  L     +  L L D     +P+ +   Y   ++  V +L+ LD++ V+ + I E A
Sbjct:  106 LFLYDNNISKISSLELLTNLQVLWLNNNIISEIEGLSMLGNLRELNLADNLIESI--GNSLDQNTNLQKLNLSGNKISSFKELTHLTRLSKLRELGLKDPQSRPNPVCMLCNYFTHILYHVPTLQRLDSYDVTSKAIKESA 244
[Close]
BLAST of Protein FAM151A vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009040.1 (pep scaffold:Pmarinus_7.0:GL479764:15668:17679:1 gene:ENSPMAG00000008181.1 transcript:ENSPMAT00000009040.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 107.071 bits (266), Expect = 2.082e-27
Identity = 63/142 (44.37%), Postives = 83/142 (58.45%), Query Frame = 3 
Query:  342 LEYCCNLVYLNLSKNFISDFSALKLCQNLNCLDLSSNLIESLPDFNFWNKISTLKFLYLHDNPIANPDSIMGLCSCPSITLLTLWDSPLALRYKYRHFVVNSVWSLKVLDNHFVSDEEIIEDANFKNSL---FRSMSEKLQV 758
            L  C +L +L+L  N I    AL  C  L  LDL SN I +LP  +FW  +  L  LYLHDNP+    +I  L +CPS+  LTL D+PL+LR  YRH  VNS+ +L+ LD   V+DEEIIE    + S    FR++S  + V
Sbjct:    7 LARCHSLRFLHLGNNCIRRVEALGSCPRLLELDLHSNQISALPWPDFWLGLPELHVLYLHDNPLGTA-AIPSLAACPSLVALTLADTPLSLRPGYRHRAVNSIATLQALDGVVVADEEIIEGLAGRASTSERFRALSPAMVV 147
[Close]
BLAST of Protein FAM151A vs. Ensembl Sea Lamprey
Match: LRRC49 (leucine rich repeat containing 49 [Source:HGNC Symbol;Acc:HGNC:25965])

HSP 1 Score: 62.7734 bits (151), Expect = 1.642e-10
Identity = 46/141 (32.62%), Postives = 73/141 (51.77%), Query Frame = 3 
Query:  273 SFDLLKSIKVLILHQQNIQKISSLEYCCNLVYLNLSKNFISDFSALKLCQNLNCLDLSSNLIESLPDFNFWNKISTLKFLYLHDNPIANPDSIMGLCSCPSITLLTLWDSPLALRYKYRHFVVNSVWSLKVLDNHFVSDEE 695
            S + L  + VL LH   I +I +L +   L  LNL+ N I+   +L+   +L  L+L  N I S+ + +    + +L+ L+L  N IAN D I+ L   PS+  + L  +PLA    YR   +  +  L+ LD   V++EE
Sbjct:  113 SLESLTKLDVLDLHGNQIVRIENLSHLSELRVLNLAGNQITHVDSLRGLHSLAELNLRRNNISSMKEVDC---LPSLQRLFLSYNNIANFDGIVCLREAPSLCEVALDGNPLAQEACYRQTALRHMGQLRQLDMKRVTEEE 250
[Close]
BLAST of Protein FAM151A vs. Ensembl Sea Lamprey
Match: cep97 (centrosomal protein 97 [Source:ZFIN;Acc:ZDB-GENE-031030-11])

HSP 1 Score: 51.2174 bits (121), Expect = 7.844e-7
Identity = 50/167 (29.94%), Postives = 77/167 (46.11%), Query Frame = 3 
Query:  285 LKSIKVLILHQQNIQKISSLEYCCNLVYLNLSKNFISDFSALKLCQNLNCLDLSSNLIESLPDFNFWNKISTLKFLYLHDNPIAN----PDSI---MGLCSCP--SITLLT---------------------LWDSPLALRYKYRHFVVNSVWSLKVLDNHFVSDEE 695
            L S+K L L + +I  I  L+  C+L +LNL+ N I     L  C +L  +DLS N I  L D    +K+S L+ L LH N + +    P  +   +G+ S     IT LT                     +  +P A    +R +V++   +L+VLD H V+ +E
Sbjct:   78 LSSLKQLNLPRNSIPAIEGLKDLCHLQWLNLAGNSIKTIEHLNGCTSLTYVDLSDNNISHLGDM---SKLSNLRTLLLHGNMVTSLRTAPTHLPPQLGILSLAENEITDLTEMSHLSCLRSLEQLSVMKNPCMLSAPSAPACDHRPYVLSWCLTLRVLDGHVVTQKE 241
[Close]
BLAST of Protein FAM151A vs. Ensembl Nematostella
Match: EDO47169 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RMV7])

HSP 1 Score: 160.614 bits (405), Expect = 5.152e-41
Identity = 90/248 (36.29%), Postives = 141/248 (56.85%), Query Frame = 3 
Query:  174 KNAENEGYFTRLSLDYLINNCSKDNKDEKDDCESFDLLKSIKVLILHQQNIQKISSLEYCCNLVYLNLSKNFISDFSALKLCQNLNCLDLSSNLIESLPDFNFWNKISTLKFLYLHDNPIANPDSIMGLCSCPSITLLTLWDSPLALRYKYRHFVVNSVWSLKVLDNHFVSDEEIIEDANFKNSLFRSMSEKLQVN---SYQTYNNHDGGAVEIDLKNFLVRINHLISHLSPVLIIQRWIRGYLIRKR 908
            +NA   G+    S + +  N         + C     L+ +  L +   ++  + S++ C NL    L+ N+I +F AL  C+ L  LDL SN I  +P   FW  +  L  ++LHDN I+  D I  + S PS+++LTL+D+PL+L+  YRH VVNS+WSLKVLD H +SDEEIIEDA F +  F ++     ++    ++  +N+D     ++    + ++NH+ +  SPVLIIQ+ IRG+L R+R
Sbjct:   36 RNAHERGFLKAASEEAIWENIG-------EKCN----LEDVNYLNMSSIHLHTVRSIDLCVNLKICVLACNYIKNFDALGHCRQLMFLDLHSNQITKIPGHKFWAGLQELTTVFLHDNGISRLDYIQLMASSPSLSILTLYDTPLSLKPSYRHHVVNSLWSLKVLDRHVISDEEIIEDATF-SGRFSALRPSFLIDLKAPFKKEHNYDEALNHVN--KLISQVNHIQAKNSPVLIIQKLIRGHLARQR 269
[Close]
BLAST of Protein FAM151A vs. Ensembl Nematostella
Match: EDO45771 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RSA0])

HSP 1 Score: 57.3806 bits (137), Expect = 1.359e-8
Identity = 50/156 (32.05%), Postives = 76/156 (48.72%), Query Frame = 3 
Query:  285 LKSIKVLILHQQNIQKISSLEYCCNLVYLNLSKNFISDFSALKLCQNLNCLDLSSNLI---------ESLPDFNFW----------NKISTLKFLYLHDNPIANPDSIMGLCSCPSITLLTLWDSPLALRYKYRHFVVNSVWSLKVLDNHFVSDEE 695
            LKS++VL+L +  I+KI++LE    L  L+L  N IS    L     L  L+L+ N I          SL + N            +++S L+ L+L  N I+  + I  L    SIT L+L  +P A    Y+  V+ SV  L+ LD   +++EE
Sbjct:   92 LKSLRVLMLGKNRIRKINNLEALTKLDVLDLHGNRISKIENLSHLTELRVLNLAGNEILKVCNISGMRSLAELNLRRNKICTVEEVDRLSNLQRLFLSFNCISRFEDINCLTRSTSITELSLDGNPFASDVTYKQTVLKSVTCLRQLDMKRITEEE 247
[Close]
BLAST of Protein FAM151A vs. Ensembl Nematostella
Match: EDO31771 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SWZ8])

HSP 1 Score: 54.6842 bits (130), Expect = 1.229e-7
Identity = 50/154 (32.47%), Postives = 71/154 (46.10%), Query Frame = 3 
Query:  321 NIQKISSLEYCCNLVYLNLSKNFISDFSALKLCQNLNCLDLSSN--------LIESLPDFNFW----NKISTLKF---------LYLHDNPIANPDSIMGLCSCPSITLLTLWDSPLALRYK-YRHFVVNSVWSLKVLDNHFVSDEE--IIEDA 710
            ++ KI   E C +L  L+L  N IS F  L     L  L+LSSN        ++E LP+  +     N I+ LK          LYL +N +AN   I  L   P + +L L+ +PL      YR FV+  + +LK LD   V   E  + +DA
Sbjct:  451 DLTKIEGFESCSSLEELSLEGNCISKFEGLVRNPKLKWLNLSSNNLTILDTGMLERLPELRYLSLENNNITCLKGLQHAVELQELYLGNNHLANIREIFSLKPIPMLVILDLYGNPLVENTANYRLFVIFHLTTLKALDGLAVEPNEGNVAKDA 604
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BLAST of Protein FAM151A vs. Ensembl Nematostella
Match: EDO44937 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RU20])

HSP 1 Score: 50.0618 bits (118), Expect = 1.396e-6
Identity = 36/127 (28.35%), Postives = 65/127 (51.18%), Query Frame = 3 
Query:  291 SIKVLILHQQNIQKISSLEYCCNLVYLNLSKNFISDFSALKLCQNLNCLDLSSNLIESLPDFNFWNKISTLKFLYLHDNPIANPDSIMGLCSCPSITLLTLWDSPLALRYKYRHFVVNSVWSLKVLD 671
            S+KVL +    I ++  LE+  +L  L +S N I +   L+    LN LDL+SN I+ + +      +  L+  + +DN + + + +  L  CP +  + L  +PL+    YR  V  ++ +LK +D
Sbjct:  182 SLKVLSIQSNRIVELKGLEHLDSLEELYISHNGIEEIKGLESLTKLNTLDLASNRIKRISNVGH---LLNLEEFWFNDNQLEHWEDLDELAKCPKLHTVYLERNPLSRDTAYRRKVKLALPALKQID 305
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BLAST of Protein FAM151A vs. Ensembl Nematostella
Match: EDO45841 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRY6])

HSP 1 Score: 47.7506 bits (112), Expect = 7.692e-6
Identity = 44/124 (35.48%), Postives = 59/124 (47.58%), Query Frame = 3 
Query:  330 KISSLEYCCNLVYLNLSKNFISDFSALKLCQNLNCLDLSSNLIESLPDFNFWNKISTLKFLYLHDNPIANPDSIMGLCSCPSITLLTLWDSPLALRYKYRHFVVNSVWSLKVLDNHFVSDEEII 701
            +  SLE   NL +   S   +SD S ++   N+  L LS N I SL DF F  +   LK LYL  N I +   I  L   P + +L L D+P      YR  V+ ++  L  LDN  V D E +
Sbjct:   14 RAKSLESVKNLNFWGSS---LSDVSLVRELPNVEVLSLSVNSIASLKDFAFCPR---LKELYLRRNCINDLKEIGFLKKLPKLRVLWLSDNPCCTTENYRETVLKNLPRLIRLDNVAVDDTEPL 131
[Close]
BLAST of Protein FAM151A vs. Ensembl Medaka
Match: ppp1r7 (protein phosphatase 1 regulatory subunit 7 [Source:NCBI gene;Acc:101158055])

HSP 1 Score: 49.6766 bits (117), Expect = 6.159e-6
Identity = 35/139 (25.18%), Postives = 71/139 (51.08%), Query Frame = 3 
Query:  267 CESFDLLKSIKVLILHQQNIQKISSLEYCCNLVYLNLSKNFISDFSALKLCQNLNCLDLSSNLIESLPDFNFWNKISTLKFLYLHDNPIANPDSIMGLCSCPSITLLTLWDSPLALRYKYRHFVVNSVWSLKVLDNHFV 683
             ++ D L ++ VL +    I KI  L+   NL  L LS N I     L+  + L  LD+++N ++ + + +    ++ L+  +++DN I N   +  L +  S+  + L  +PL    +YR  ++ ++ S++ +D  F+
Sbjct:  209 LQNLDALHNLSVLSIQSNRITKIEGLQNLVNLKELYLSHNGIEVIEGLENNKKLTTLDIAANRVKKIENISH---LTELQEFWMNDNQIENWSDLDELKNAKSLETVYLERNPLQKDPQYRRKIMLALPSVRQIDATFI 344
[Close]
BLAST of Protein FAM151A vs. Planmine SMEST
Match: SMESG000000164.1 (SMESG000000164.1)

HSP 1 Score: 1358.58 bits (3515), Expect = 0.000e+0
Identity = 680/686 (99.13%), Postives = 683/686 (99.56%), Query Frame = 3 
Query:   63 MVSIPSSQIKNIIYFDISAQKLSNKITKPQTNIRLAIKNAENEGYFTRLSLDYLINNCSKDNKDEKDDCESFDLLKSIKVLILHQQNIQKISSLEYCCNLVYLNLSKNFISDFSALKLCQNLNCLDLSSNLIESLPDFNFWNKISTLKFLYLHDNPIANPDSIMGLCSCPSITLLTLWDSPLALRYKYRHFVVNSVWSLKVLDNHFVSDEEIIEDANFKNSLFRSMSEKLQVNSYQTYNNHDGGAVEIDLKNFLVRINHLISHLSPVLIIQRWIRGYLIRKRYEXXXXXXXXXXXXXPQIARSPIAAVKENSEHQENVKYLKIDLLHLNKNSTLENIDKEASIRSLITSTLNMLTYRSFIKQDQDKCSPEHISRALKSDTFTVDDPGNCYNLDEKISFKFRGSKPPISTKTIATEVKNEKSRSHYFIREADRNYHDQILTQLPVIKSKPLKKINSSILFRKAQDCMSLFLLNKWDKADRDIQDVQRFHEKMATVRMIKVDREVNQMKLEDAKLNKLALIRQQHKDLKSVVERSLETDKKNNKIAGELVKMKKMEATDRRMKMMQEMGFSQDFRSKQTAASKAVDKFEQTTYKQEQLESNKVAVDETRQKMKVEKETVKAYLENQAINRRTERTLENSALDVQILQQTNSRINDAKMRVEKLKAIHRLVSCPQLPVIQLSAATVKNS 2120
            MVSIPSSQIKNIIYFDISAQKLSNKITKPQTNIRLAIKNAENEGYFTRLSLDYLINNCSKDNKD   DCESFDLLKSIKVLILHQQNIQKISSLEYCCNLVYLNLSKNFISDFSALKLCQNLNCLDLSSNLIESLPDFNFWNKISTLKFLYLHDNPIANPDSI+GLCSCPSITLLTLWDSPLALRYKYRHFVVNSVWSLKVLDNHFVSDEEIIEDANFKNSLFRSMSEKLQVNSYQTYNNHDGGAVEIDLKNFLVRINHLISHLSPVLIIQRWIRGYLIRKRYEKSKSVSSKLNVNLPQIARSPIAAVKENSEHQENVKYLKIDLLHLNKNSTLENIDKEASIRSLITSTLNMLTYRSFIKQDQDKCSPEHISRALKSDTFTVDDPGNCYNLDEKISFKFRGSKPPISTKTIATEVKNEKSRSHYFIREADRNYHDQILTQLPVIKSKPLKKINSSILFRKAQDCMSLFLLNKWDKADRDIQDVQRFHEKMATV+MIKVDREVNQMKLE+AKLNKLALIRQQHKDLKSVVERSLETDKKNNKIAGELVKMKKMEATDRRMKMMQEMGFSQDFRSKQTAASKAVDKFEQTTYKQEQLESNKVAVDETRQKMKVEKETVKAYLENQAINRRTERTLENSALDVQILQQTNSRINDAKMRVEKLKAIHRLVSCPQLPVIQLSAATVKNS
Sbjct:    1 MVSIPSSQIKNIIYFDISAQKLSNKITKPQTNIRLAIKNAENEGYFTRLSLDYLINNCSKDNKD---DCESFDLLKSIKVLILHQQNIQKISSLEYCCNLVYLNLSKNFISDFSALKLCQNLNCLDLSSNLIESLPDFNFWNKISTLKFLYLHDNPIANPDSIIGLCSCPSITLLTLWDSPLALRYKYRHFVVNSVWSLKVLDNHFVSDEEIIEDANFKNSLFRSMSEKLQVNSYQTYNNHDGGAVEIDLKNFLVRINHLISHLSPVLIIQRWIRGYLIRKRYEKSKSVSSKLNVNLPQIARSPIAAVKENSEHQENVKYLKIDLLHLNKNSTLENIDKEASIRSLITSTLNMLTYRSFIKQDQDKCSPEHISRALKSDTFTVDDPGNCYNLDEKISFKFRGSKPPISTKTIATEVKNEKSRSHYFIREADRNYHDQILTQLPVIKSKPLKKINSSILFRKAQDCMSLFLLNKWDKADRDIQDVQRFHEKMATVQMIKVDREVNQMKLEEAKLNKLALIRQQHKDLKSVVERSLETDKKNNKIAGELVKMKKMEATDRRMKMMQEMGFSQDFRSKQTAASKAVDKFEQTTYKQEQLESNKVAVDETRQKMKVEKETVKAYLENQAINRRTERTLENSALDVQILQQTNSRINDAKMRVEKLKAIHRLVSCPQLPVIQLSAATVKNS 683
[Close]
BLAST of Protein FAM151A vs. Planmine SMEST
Match: SMESG000006866.1 (SMESG000006866.1)

HSP 1 Score: 54.299 bits (129), Expect = 3.967e-7
Identity = 49/162 (30.25%), Postives = 78/162 (48.15%), Query Frame = 3 
Query:  270 ESFDLLKSIKVLILHQQNIQKISSLEYCCNLVYLNLSKNFISDFSALKLCQNLNCLDLSSNLIESLPDFNFWNKISTLKFLYLHDNPIANPDSIMGLCSCPSITLLTLWDSPLALRYKYRHFVVNSVWSLKVLDNHFV-SDEEIIEDANFKNSLFRSMSEKL 752
            E  D L +I VL +    I+KI  L+  CNL  L LS+N I     L+   NL  LD+  N + S+P + F  +   L  +    N   + + I  L +   +  L + ++P+A    YR ++V  +  L +LDN  V +DE+ I    F+ +    MS +L
Sbjct:   44 EHLDNLNNITVLSIRFHAIEKIEKLDKLCNLRELYLSENKIIRLDGLENLLNLKILDVRGNQLNSIPHW-FTRRCKYLTKINFSRNMFDSIEEISKLWTLKDLLDLDVSENPVAAIAHYRLYIVMRLKYLLILDNREVLADEKKIAIEQFEENELDRMSSRL 204
The following BLAST results are available for this feature:
BLAST of Protein FAM151A vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
LRRIQ36.202e-4141.33leucine rich repeats and IQ motif containing 3 [So... [more]
LRRIQ36.477e-4041.33leucine rich repeats and IQ motif containing 3 [So... [more]
LRRIQ36.477e-4041.33leucine rich repeats and IQ motif containing 3 [So... [more]
LRRIQ34.517e-3041.50leucine rich repeats and IQ motif containing 3 [So... [more]
LRRC491.426e-1032.85leucine rich repeat containing 49 [Source:HGNC Sym... [more]
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BLAST of Protein FAM151A vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1
Match NameE-valueIdentityDescription
F13E9.18.062e-630.95pep chromosome:WBcel235:IV:10864331:10873632:1 gen... [more]
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BLAST of Protein FAM151A vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Protein FAM151A vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 3
Match NameE-valueIdentityDescription
lrriq38.129e-3538.46leucine-rich repeats and IQ motif containing 3 [So... [more]
lrriq31.059e-2538.16leucine-rich repeats and IQ motif containing 3 [So... [more]
lrrc95.228e-631.51leucine rich repeat containing 9 [Source:ZFIN;Acc:... [more]
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BLAST of Protein FAM151A vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
chrna74.333e-3441.32cholinergic receptor, nicotinic alpha 7 [Source:Xe... [more]
CNTRL1.030e-831.61centriolin [Source:NCBI gene;Acc:100270771][more]
CNTRL1.038e-831.21centriolin [Source:NCBI gene;Acc:100270771][more]
CNTRL1.042e-831.61centriolin [Source:NCBI gene;Acc:100270771][more]
rbpms21.700e-831.41RNA binding protein with multiple splicing 2 [Sour... [more]
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BLAST of Protein FAM151A vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Lrriq31.476e-4141.62leucine-rich repeats and IQ motif containing 3 [So... [more]
Lrriq32.867e-4141.62leucine-rich repeats and IQ motif containing 3 [So... [more]
Lrriq32.038e-4041.84leucine-rich repeats and IQ motif containing 3 [So... [more]
Nisch8.174e-830.95nischarin [Source:MGI Symbol;Acc:MGI:1928323][more]
Nisch9.169e-830.95nischarin [Source:MGI Symbol;Acc:MGI:1928323][more]
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BLAST of Protein FAM151A vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q6AYL8|LRIQ3_RAT4.252e-4041.33Leucine-rich repeat and IQ domain-containing prote... [more]
sp|Q14DL3|LRIQ3_MOUSE1.426e-3941.84Leucine-rich repeat and IQ domain-containing prote... [more]
sp|A6PVS8|LRIQ3_HUMAN3.111e-3941.33Leucine-rich repeat and IQ domain-containing prote... [more]
sp|Q8IUZ0|LRC49_HUMAN7.826e-1032.85Leucine-rich repeat-containing protein 49 OS=Homo ... [more]
sp|Q80TM9|NISCH_MOUSE5.718e-730.95Nischarin OS=Mus musculus OX=10090 GN=Nisch PE=1 S... [more]
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BLAST of Protein FAM151A vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A2C9LCG71.010e-5326.91Uncharacterized protein OS=Biomphalaria glabrata O... [more]
C3Y2J85.208e-5041.04Uncharacterized protein OS=Branchiostoma floridae ... [more]
A0A210R1372.216e-4740.96Leucine-rich repeat and IQ domain-containing prote... [more]
A0A2T7NKM46.385e-4538.40Uncharacterized protein OS=Pomacea canaliculata OX... [more]
H2YJZ81.246e-4436.92Uncharacterized protein OS=Ciona savignyi OX=51511... [more]
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BLAST of Protein FAM151A vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
lrriq38.229e-3841.75leucine-rich repeats and IQ motif containing 3 [So... [more]
ENSAMXT00000021515.27.531e-731.21leucine rich repeat containing 49 [Source:NCBI gen... [more]
LRRC91.748e-633.33leucine-rich repeat-containing protein 9-like [Sou... [more]
LRRC91.850e-633.33leucine-rich repeat-containing protein 9-like [Sou... [more]
LRRC92.061e-633.33leucine-rich repeat-containing protein 9-like [Sou... [more]
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BLAST of Protein FAM151A vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 3
Match NameE-valueIdentityDescription
ENSPMAT00000009040.12.082e-2744.37pep scaffold:Pmarinus_7.0:GL479764:15668:17679:1 g... [more]
LRRC491.642e-1032.62leucine rich repeat containing 49 [Source:HGNC Sym... [more]
cep977.844e-729.94centrosomal protein 97 [Source:ZFIN;Acc:ZDB-GENE-0... [more]
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BLAST of Protein FAM151A vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Protein FAM151A vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO471695.152e-4136.29Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO457711.359e-832.05Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO317711.229e-732.47Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO449371.396e-628.35Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO458417.692e-635.48Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Protein FAM151A vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
ppp1r76.159e-625.18protein phosphatase 1 regulatory subunit 7 [Source... [more]
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BLAST of Protein FAM151A vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 2
Match NameE-valueIdentityDescription
SMESG000000164.10.000e+099.13SMESG000000164.1[more]
SMESG000006866.13.967e-730.25SMESG000006866.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30019240 ID=SMED30019240|Name=Protein FAM151A|organism=Schmidtea mediterranea sexual|type=transcript|length=2156bp
GTCTTATCGAAATCTATGTAAATCTTATATGTTTAAAAATATTTAAAGAT
CTAATTATTGAAATGGTCAGTATTCCAAGCAGTCAAATAAAGAATATTAT
ATATTTTGATATCAGTGCTCAGAAACTAAGTAATAAAATTACAAAACCAC
AAACAAATATCAGATTAGCAATAAAAAACGCAGAAAATGAGGGATATTTC
ACTCGTTTATCCTTAGACTATTTAATAAATAACTGCAGTAAAGATAACAA
AGATGAAAAAGATGATTGTGAAAGTTTCGATCTGCTTAAATCAATTAAAG
TGCTCATTTTGCACCAACAAAACATCCAAAAAATCAGCAGCCTAGAATAC
TGCTGCAATTTAGTCTATTTAAACCTCTCTAAAAATTTCATTTCCGATTT
TTCAGCTTTGAAACTTTGTCAAAATTTGAATTGTTTAGATTTGTCATCGA
ATTTGATAGAAAGTCTTCCAGATTTCAATTTTTGGAATAAGATTAGCACT
TTGAAATTTCTTTATTTACACGACAATCCTATTGCTAATCCAGATTCAAT
AATGGGGCTATGTAGCTGTCCCAGCATCACGTTACTAACGCTCTGGGACT
CCCCTCTTGCCCTTCGATACAAATATCGGCATTTTGTCGTCAATTCAGTA
TGGTCATTAAAGGTTTTGGATAATCATTTTGTTTCCGATGAAGAAATTAT
TGAAGACGCTAATTTCAAGAATTCTCTGTTTAGGTCTATGAGTGAAAAGC
TTCAAGTTAACAGCTATCAGACCTATAATAATCATGATGGAGGTGCAGTT
GAAATAGATCTCAAAAATTTCCTTGTGAGAATAAACCATTTAATTTCTCA
CTTATCTCCAGTTTTAATCATACAAAGGTGGATTAGAGGATATTTGATTC
GCAAGCGATATGAAAAGTCGAAATCAGTCTCTTCAAAATTGAATGTGAAT
TTACCACAGATTGCCAGATCCCCAATTGCAGCAGTCAAAGAAAATAGTGA
ACACCAAGAAAATGTGAAATATCTCAAAATTGACCTACTGCATCTCAATA
AAAATTCAACTTTGGAAAATATAGACAAAGAGGCCAGCATCAGAAGTTTA
ATTACGTCGACATTAAACATGTTAACGTATAGATCATTTATTAAACAGGA
CCAAGACAAATGTTCTCCGGAGCACATTTCGAGGGCTTTGAAAAGCGACA
CTTTTACCGTCGATGATCCAGGAAATTGCTACAATTTAGATGAGAAAATA
TCTTTCAAATTCCGAGGCTCTAAACCGCCAATTTCTACGAAGACTATAGC
AACCGAAGTAAAAAATGAGAAAAGTCGCTCGCATTACTTTATTCGAGAAG
CAGATAGAAATTATCACGATCAAATTTTGACTCAGTTGCCGGTAATTAAA
AGCAAACCATTGAAAAAAATCAACAGCAGCATTCTTTTCCGTAAAGCCCA
AGATTGCATGAGTCTCTTTCTGTTGAATAAATGGGACAAGGCTGATCGCG
ATATACAGGATGTTCAGAGATTCCATGAGAAAATGGCGACTGTGCGAATG
ATCAAAGTCGATAGAGAAGTAAATCAAATGAAATTGGAAGATGCCAAATT
AAACAAATTAGCTTTAATTCGACAGCAACATAAAGATCTTAAATCTGTCG
TGGAAAGGTCTCTGGAAACTGATAAGAAAAATAATAAAATAGCTGGAGAG
TTGGTAAAAATGAAGAAAATGGAGGCGACTGATAGACGAATGAAAATGAT
GCAAGAAATGGGATTTTCACAGGATTTTAGATCAAAGCAAACTGCGGCTT
CTAAAGCAGTTGACAAGTTCGAGCAGACAACATATAAACAAGAACAGCTA
GAATCGAATAAAGTTGCTGTGGATGAAACGAGACAAAAAATGAAAGTTGA
AAAGGAAACTGTGAAAGCTTACTTAGAAAATCAAGCGATCAATCGACGAA
CAGAAAGAACTCTTGAGAATTCAGCTTTGGACGTCCAAATCCTTCAACAG
ACGAACAGCCGCATAAATGACGCCAAAATGCGGGTAGAGAAACTGAAGGC
GATTCATAGGCTCGTATCCTGTCCACAATTGCCTGTCATTCAGTTAAGTG
CAGCAACTGTGAAAAATTCATAATTTTATTCATAAATTTAATATTTGTGA
TATTTT
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protein sequence of SMED30019240-orf-1

>SMED30019240-orf-1 ID=SMED30019240-orf-1|Name=SMED30019240-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=707bp
LIEIYVNLICLKIFKDLIIEMVSIPSSQIKNIIYFDISAQKLSNKITKPQ
TNIRLAIKNAENEGYFTRLSLDYLINNCSKDNKDEKDDCESFDLLKSIKV
LILHQQNIQKISSLEYCCNLVYLNLSKNFISDFSALKLCQNLNCLDLSSN
LIESLPDFNFWNKISTLKFLYLHDNPIANPDSIMGLCSCPSITLLTLWDS
PLALRYKYRHFVVNSVWSLKVLDNHFVSDEEIIEDANFKNSLFRSMSEKL
QVNSYQTYNNHDGGAVEIDLKNFLVRINHLISHLSPVLIIQRWIRGYLIR
KRYEKSKSVSSKLNVNLPQIARSPIAAVKENSEHQENVKYLKIDLLHLNK
NSTLENIDKEASIRSLITSTLNMLTYRSFIKQDQDKCSPEHISRALKSDT
FTVDDPGNCYNLDEKISFKFRGSKPPISTKTIATEVKNEKSRSHYFIREA
DRNYHDQILTQLPVIKSKPLKKINSSILFRKAQDCMSLFLLNKWDKADRD
IQDVQRFHEKMATVRMIKVDREVNQMKLEDAKLNKLALIRQQHKDLKSVV
ERSLETDKKNNKIAGELVKMKKMEATDRRMKMMQEMGFSQDFRSKQTAAS
KAVDKFEQTTYKQEQLESNKVAVDETRQKMKVEKETVKAYLENQAINRRT
ERTLENSALDVQILQQTNSRINDAKMRVEKLKAIHRLVSCPQLPVIQLSA
ATVKNS*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0008270zinc ion binding
GO:0016491oxidoreductase activity
GO:0005515protein binding
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
Vocabulary: biological process
TermDefinition
GO:0055114oxidation-reduction process
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000034epidermis
PLANA:0000418head
PLANA:0002032epidermal cell
Vocabulary: INTERPRO
TermDefinition
IPR000048IQ_motif_EF-hand-BS
IPR032675LRR_dom_sf
IPR001611Leu-rich_rpt
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 610..630
NoneNo IPR availableCOILSCoilCoilcoord: 651..671
NoneNo IPR availablePFAMPF14580LRR_9coord: 110..219
e-value: 1.9E-7
score: 30.8
NoneNo IPR availablePANTHERPTHR46723FAMILY NOT NAMEDcoord: 46..292
coord: 337..677
NoneNo IPR availableSUPERFAMILYSSF52058L domain-likecoord: 79..217
IPR032675Leucine-rich repeat domain superfamilyGENE3DG3DSA:3.80.10.10coord: 68..233
e-value: 2.4E-25
score: 90.5
IPR000048IQ motif, EF-hand binding sitePFAMPF00612IQcoord: 275..290
e-value: 2.6E-4
score: 20.5
IPR000048IQ motif, EF-hand binding sitePROSITEPS50096IQcoord: 270..299
score: 8.334
IPR001611Leucine-rich repeatPROSITEPS51450LRRcoord: 153..174
score: 6.857
IPR001611Leucine-rich repeatPROSITEPS51450LRRcoord: 84..105
score: 6.133
IPR001611Leucine-rich repeatPROSITEPS51450LRRcoord: 128..149
score: 8.975
IPR001611Leucine-rich repeatPROSITEPS51450LRRcoord: 106..127
score: 7.974