RIC1 domain-containing protein
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30019230 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 5
Homology
BLAST of RIC1 domain-containing protein vs. Ensembl Human
Match: RIC1 (RIC1 homolog, RAB6A GEF complex partner 1 [Source:HGNC Symbol;Acc:HGNC:17686]) HSP 1 Score: 541.576 bits (1394), Expect = 1.287e-168 Identity = 354/1033 (34.27%), Postives = 541/1033 (52.37%), Query Frame = 3
Query: 21 MYYFFNCPKRI-----SRHFVPSNITGIISSKSFALCAIFNSSQIIVFENKNNSIVAYYCRCEESLDIYGNSINLEWNSDGSLIAIGTDKGFLLIFSVKT----------VSQEVNVGYQNEKEFLEEGFINRQLSLFGEIILLDVISFPYKISCICLYRDDLLVAIEDGTLSRIKWNGSLLYNQEFNLTSISFFSDLEFSK-ASNLSKNEAICRNIEWLPSLSGVIVLFKNGKSAFLHIPNHKLLSEQITGVWAENLRNVTCSAVNVKFRSIAYGLKIGEAVIYKTDEETGALRLQHRLKILSNEYPDADKVTGAVTYLKWSPDNFCLALCWEYIGFSLWSVQGSLLFSSLGNKAGI--------DMSLLSLDWGCEGYSLWLI----------EKPDKS--GKPAILIFQMAKSVLVVNPTKNNHEHXXXXXXXHIIFG---------PRKLLSSSETNLEYIPYPE------------------------------NYVTWNWPIKYAAIDLNGSRLVISGKHGFALYFFVSKKWRLFGNETQERTIEVSGGIVWYNHIVGLACFDNKEGKFEIRLYDSLQKIDNSLSTNHPVNSQILLMNIFDNTLVVLSIDGSIGLFEITLNEKSHDIS--MEYIQTIPLENYIEFAACIVSFNLSSLHTEIGHNKDVDELIR-YQSLLINYSGHLLLFQRDKSFSAPRTSDKSLNSQENSFFKLAFKNTLIAKQKITFTGPLVVAYNVEIMWTPIIDEEFQSKRLKLDDWNAKIYTMENSLWLNCGSQGLRVWLPLNGGSNVTQVGEKKSKYSFLSKRIMLTFKIRNFYPLVVLNNEALLMSPMNE-------FSNDFVNTPTCLNLSFSSINKNRHIFLQHIVKELLRINLGIHALDLTFELKKLPYFNHSXXXXXXXXXXXXATSKEPIPDPLLPRVVAFIQEFPNFLRTVVQCARKTELALWSYLFESAGNPKDLFESCLMNNELDTAASYLIILQNIEHPLISQKQAILLLDAALNRSNWGLVSNLIRFLKNI 2864
MY+ PKR+ S P ++ S A A+ ++++ ++ ++ + ++ Y +S +G+ EW D ++IA+ T G++L F + + V + + + F EE Q + + + ++ I + +DLLVA DG L I W G + NL ++ F DL+ S+ S L + R++E+ +L G V+F +GK F+ + + +EQ+ GVW +++ + TC AVN K+R +A+G G +Y D TGA+ L H+L++ + +YPD TGAV ++WSPDN + + WEY G SLWSV G+ L +LG + + S+ WG EGY LW+I E +S +P+IL+FQ KSVL VNP +N E +LL + PR SS T+ E+ P E Y+ NWPI+++AID G + + GK GFA Y ++KKW+LFGN TQE+ + V+GG+ W+N + LAC++ + + E+R+Y +DN+ + ++ LL+++F + ++V D SI L+ I + + ++ +Q + + YI +VS L+S+ TE G + + R +S+++N +G L++ QRD+S R D + N+Q ++ + F P+V+A +VE +WT + KR L+ +LWL+CG G++VWLPL + + +SFLS+RIML F I N YPL VL +AL++ +N+ ++ + + F + + I+L HI+++LL NLG AL L LPYF H LEL+LHEVLEEEATS+EPIPDPLLP V FI EFP FL+TVV CARKTE ALW+YLF + GNPKDLFE CLM +LDTAASYLIILQN+E P +S++ A LL + AL + W L ++IRFLK I
Sbjct: 1 MYFLSGWPKRLLCPLGSPAEAPFHVQ---SDPQRAFFAVLAAARLSIWYSRPSVLIVTYKEPAKSSTQFGSYKQAEWRPDSTMIAVSTANGYILFFHITSTRGDKYLYEPVYPKGSPQMKGTPHFKEE-----QCAPALNLEMRKILDLQAPIMSLQSVLEDLLVATSDGLLHLIHWEGMTNGRKAINLCTVPFSVDLQSSRVGSFLGFTDVHIRDMEYCATLDGFAVVFNDGKVGFITPVSSRFTAEQLHGVWPQDVVDGTCVAVNNKYRLMAFGCVSGSVQVYTIDNSTGAMLLSHKLELTAKQYPDIWNKTGAVKLMRWSPDNSVVIVTWEYGGLSLWSVFGAQLICTLGGDFAYRSDGTKKDPLKINSMSWGAEGYHLWVISGFGSQNTEIESDLRSVVKQPSILLFQFIKSVLTVNPCMSNQEQVLLQGEDRLYLNCGEASQTQNPR----SSSTHSEHKPSREKSPFADGGLESQGLSTLLGHRHWHVVQISSTYLESNWPIRFSAIDKLGQNIAVVGKFGFAHYSLLTKKWKLFGNITQEQNMIVTGGLAWWNDFMVLACYNINDRQEELRVYLRTSNLDNAFAHVTKAQAETLLLSVFQDMVIVFRADCSICLYSIERKSDGPNTTAGIQVLQEVSMSRYIPHPFLVVSVTLTSVSTENGITLKMPQQARGAESIMLNLAGQLIMMQRDRSGPQIREKDSNPNNQ---------------RKLLPFCPPVVLAQSVENVWTTC--RANKQKRHLLE-----------ALWLSCGGAGMKVWLPLFPR-------DHRKPHSFLSQRIMLPFHI-NIYPLAVLFEDALVLGAVNDTLLYDSLYTRNNAREQLEVLFPFCVVERTSQIYLHHILRQLLVRNLGEQALLLAQSCATLPYFPHVLELMLHEVLEEEATSREPIPDPLLPTVAKFITEFPLFLQTVVHCARKTEYALWNYLFAAVGNPKDLFEECLMAQDLDTAASYLIILQNMEVPAVSRQHATLLFNTALEQGKWDLCRHMIRFLKAI 985
BLAST of RIC1 domain-containing protein vs. Ensembl Human
Match: RIC1 (RIC1 homolog, RAB6A GEF complex partner 1 [Source:HGNC Symbol;Acc:HGNC:17686]) HSP 1 Score: 543.502 bits (1399), Expect = 9.980e-167 Identity = 354/1033 (34.27%), Postives = 541/1033 (52.37%), Query Frame = 3
Query: 21 MYYFFNCPKRI-----SRHFVPSNITGIISSKSFALCAIFNSSQIIVFENKNNSIVAYYCRCEESLDIYGNSINLEWNSDGSLIAIGTDKGFLLIFSVKT----------VSQEVNVGYQNEKEFLEEGFINRQLSLFGEIILLDVISFPYKISCICLYRDDLLVAIEDGTLSRIKWNGSLLYNQEFNLTSISFFSDLEFSK-ASNLSKNEAICRNIEWLPSLSGVIVLFKNGKSAFLHIPNHKLLSEQITGVWAENLRNVTCSAVNVKFRSIAYGLKIGEAVIYKTDEETGALRLQHRLKILSNEYPDADKVTGAVTYLKWSPDNFCLALCWEYIGFSLWSVQGSLLFSSLGNKAGI--------DMSLLSLDWGCEGYSLWLI----------EKPDKS--GKPAILIFQMAKSVLVVNPTKNNHEHXXXXXXXHIIFG---------PRKLLSSSETNLEYIPYPE------------------------------NYVTWNWPIKYAAIDLNGSRLVISGKHGFALYFFVSKKWRLFGNETQERTIEVSGGIVWYNHIVGLACFDNKEGKFEIRLYDSLQKIDNSLSTNHPVNSQILLMNIFDNTLVVLSIDGSIGLFEITLNEKSHDIS--MEYIQTIPLENYIEFAACIVSFNLSSLHTEIGHNKDVDELIR-YQSLLINYSGHLLLFQRDKSFSAPRTSDKSLNSQENSFFKLAFKNTLIAKQKITFTGPLVVAYNVEIMWTPIIDEEFQSKRLKLDDWNAKIYTMENSLWLNCGSQGLRVWLPLNGGSNVTQVGEKKSKYSFLSKRIMLTFKIRNFYPLVVLNNEALLMSPMNE-------FSNDFVNTPTCLNLSFSSINKNRHIFLQHIVKELLRINLGIHALDLTFELKKLPYFNHSXXXXXXXXXXXXATSKEPIPDPLLPRVVAFIQEFPNFLRTVVQCARKTELALWSYLFESAGNPKDLFESCLMNNELDTAASYLIILQNIEHPLISQKQAILLLDAALNRSNWGLVSNLIRFLKNI 2864
MY+ PKR+ S P ++ S A A+ ++++ ++ ++ + ++ Y +S +G+ EW D ++IA+ T G++L F + + V + + + F EE Q + + + ++ I + +DLLVA DG L I W G + NL ++ F DL+ S+ S L + R++E+ +L G V+F +GK F+ + + +EQ+ GVW +++ + TC AVN K+R +A+G G +Y D TGA+ L H+L++ + +YPD TGAV ++WSPDN + + WEY G SLWSV G+ L +LG + + S+ WG EGY LW+I E +S +P+IL+FQ KSVL VNP +N E +LL + PR SS T+ E+ P E Y+ NWPI+++AID G + + GK GFA Y ++KKW+LFGN TQE+ + V+GG+ W+N + LAC++ + + E+R+Y +DN+ + ++ LL+++F + ++V D SI L+ I + + ++ +Q + + YI +VS L+S+ TE G + + R +S+++N +G L++ QRD+S R D + N+Q ++ + F P+V+A +VE +WT + KR L+ +LWL+CG G++VWLPL + + +SFLS+RIML F I N YPL VL +AL++ +N+ ++ + + F + + I+L HI+++LL NLG AL L LPYF H LEL+LHEVLEEEATS+EPIPDPLLP V FI EFP FL+TVV CARKTE ALW+YLF + GNPKDLFE CLM +LDTAASYLIILQN+E P +S++ A LL + AL + W L ++IRFLK I
Sbjct: 1 MYFLSGWPKRLLCPLGSPAEAPFHVQ---SDPQRAFFAVLAAARLSIWYSRPSVLIVTYKEPAKSSTQFGSYKQAEWRPDSTMIAVSTANGYILFFHITSTRGDKYLYEPVYPKGSPQMKGTPHFKEE-----QCAPALNLEMRKILDLQAPIMSLQSVLEDLLVATSDGLLHLIHWEGMTNGRKAINLCTVPFSVDLQSSRVGSFLGFTDVHIRDMEYCATLDGFAVVFNDGKVGFITPVSSRFTAEQLHGVWPQDVVDGTCVAVNNKYRLMAFGCVSGSVQVYTIDNSTGAMLLSHKLELTAKQYPDIWNKTGAVKLMRWSPDNSVVIVTWEYGGLSLWSVFGAQLICTLGGDFAYRSDGTKKDPLKINSMSWGAEGYHLWVISGFGSQNTEIESDLRSVVKQPSILLFQFIKSVLTVNPCMSNQEQVLLQGEDRLYLNCGEASQTQNPR----SSSTHSEHKPSREKSPFADGGLESQGLSTLLGHRHWHVVQISSTYLESNWPIRFSAIDKLGQNIAVVGKFGFAHYSLLTKKWKLFGNITQEQNMIVTGGLAWWNDFMVLACYNINDRQEELRVYLRTSNLDNAFAHVTKAQAETLLLSVFQDMVIVFRADCSICLYSIERKSDGPNTTAGIQVLQEVSMSRYIPHPFLVVSVTLTSVSTENGITLKMPQQARGAESIMLNLAGQLIMMQRDRSGPQIREKDSNPNNQ---------------RKLLPFCPPVVLAQSVENVWTTC--RANKQKRHLLE-----------ALWLSCGGAGMKVWLPLFPR-------DHRKPHSFLSQRIMLPFHI-NIYPLAVLFEDALVLGAVNDTLLYDSLYTRNNAREQLEVLFPFCVVERTSQIYLHHILRQLLVRNLGEQALLLAQSCATLPYFPHVLELMLHEVLEEEATSREPIPDPLLPTVAKFITEFPLFLQTVVHCARKTEYALWNYLFAAVGNPKDLFEECLMAQDLDTAASYLIILQNMEVPAVSRQHATLLFNTALEQGKWDLCRHMIRFLKAI 985
BLAST of RIC1 domain-containing protein vs. Ensembl Human
Match: RIC1 (RIC1 homolog, RAB6A GEF complex partner 1 [Source:HGNC Symbol;Acc:HGNC:17686]) HSP 1 Score: 497.664 bits (1280), Expect = 2.542e-150 Identity = 334/1006 (33.20%), Postives = 522/1006 (51.89%), Query Frame = 3
Query: 21 MYYFFNCPKRI-----SRHFVPSNITGIISSKSFALCAIFNSSQIIVFENKNNSIVAYYCRCEESLDIYGNSINLEWNSDGSLIAIGTDKGFLLIFSVKT----------VSQEVNVGYQNEKEFLEEGFINRQLSLFGEIILLDVISFPYKISCICLYRDDLLVAIEDGTLSRIKWNGSLLYNQEFNLTSISFFSDLEFSK-ASNLSKNEAICRNIEWLPSLSGVIVLFKNGKSAFLHIPNHKLLSEQITGVWAENLRNVTCSAVNVKFRSIAYGLKIGEAVIYKTDEETGALRLQHRLKILSNEYPDADKVTGAVTYLKWSPDNFCLALCWEYIGFSLWSVQGSLLFSSLGNKAGI--------DMSLLSLDWGCEGYSLWLI----------EKPDKS--GKPAILIFQMAKSVLVVNPTKNNHEHXXXXXXXHIIFG---------PRKLLSSSETNLEYIPYPENYVTWNWPIKYAAIDLNGSRLVISGKHGFALYF---FVSKKWRLFGNETQERTIEVSGGIVWYNHIVGLACFDNKEGKFEIRLYDSLQKIDNSLSTNHPVNSQILLMNIFDNTLVVLSIDGSIGLFEITLNEKSHDIS--MEYIQTIPLENYIEFAACIVSFNLSSLHTEIGHNKDVDELIR-YQSLLINYSGHLLLFQRDKSFSAPRTSDKSLNSQENSFFKLAFKNTLIAKQKITFTGPLVVAYNVEIMWTPIIDEEFQSKRLKLDDWNAKIYTMENSLWLNCGSQGLRVWLPLNGGSNVTQVGEKKSKYSFLSKRIMLTFKIRNFYPLVVLNNEALLMSPMNE-------FSNDFVNTPTCLNLSFSSINKNRHIFLQHIVKELLRINLGIHALDLTFELKKLPYFNHSXXXXXXXXXXXXATSKEPIPDPLLPRVVAFIQEFPNFLRTVVQCARKTELALWSYLFESAGNPKDLFESCLMNNELDTAASYLIILQNIEHPLISQKQAILLLDAALNRSNWGLVSNLIRFLKNI 2864
MY+ PKR+ S P ++ S A A+ ++++ ++ ++ + ++ Y +S +G+ EW D ++IA+ T G++L F + + V + + + F EE Q + + + ++ I + +DLLVA DG L I W G + NL ++ F DL+ S+ S L + R++E+ +L G V+F +GK F+ + + +EQ+ GVW +++ + TC AVN K+R +A+G G +Y D TGA+ L H+L++ + +YPD TGAV ++WSPDN + + WEY G SLWSV G+ L +LG + + S+ WG EGY LW+I E +S +P+IL+FQ KSVL VNP +N E +LL + PR SS T+ E+ P E P ++ G ++ +H + ++ W + +E+ + V+GG+ W+N + LAC++ + + E+R+Y +DN+ + ++ LL+++F + ++V D SI L+ I + + ++ +Q + + YI +VS L+S+ TE G + + R +S+++N +G L++ QRD+S R D + N+Q ++ + F P+V+A +VE +WT + KR L+ +LWL+CG G++VWLPL + + +SFLS+RIML F I N YPL VL +AL++ +N+ ++ + + F + + I+L HI+++LL NLG AL L LPYF H LEL+LHEVLEEEATS+EPIPDPLLP V FI EFP FL+TVV CARKTE ALW+YLF + GNPKDLFE CLM +LDTAASYLIILQN+E P +S++ A LL + AL + W L ++IRFLK I
Sbjct: 1 MYFLSGWPKRLLCPLGSPAEAPFHVQ---SDPQRAFFAVLAAARLSIWYSRPSVLIVTYKEPAKSSTQFGSYKQAEWRPDSTMIAVSTANGYILFFHITSTRGDKYLYEPVYPKGSPQMKGTPHFKEE-----QCAPALNLEMRKILDLQAPIMSLQSVLEDLLVATSDGLLHLIHWEGMTNGRKAINLCTVPFSVDLQSSRVGSFLGFTDVHIRDMEYCATLDGFAVVFNDGKVGFITPVSSRFTAEQLHGVWPQDVVDGTCVAVNNKYRLMAFGCVSGSVQVYTIDNSTGAMLLSHKLELTAKQYPDIWNKTGAVKLMRWSPDNSVVIVTWEYGGLSLWSVFGAQLICTLGGDFAYRSDGTKKDPLKINSMSWGAEGYHLWVISGFGSQNTEIESDLRSVVKQPSILLFQFIKSVLTVNPCMSNQEQVLLQGEDRLYLNCGEASQTQNPR----SSSTHSEHKPSREKS-----PFADGGLESQGLSTLLGHRHWHVVQISSTYLESNWPI-----REQNMIVTGGLAWWNDFMVLACYNINDRQEELRVYLRTSNLDNAFAHVTKAQAETLLLSVFQDMVIVFRADCSICLYSIERKSDGPNTTAGIQVLQEVSMSRYIPHPFLVVSVTLTSVSTENGITLKMPQQARGAESIMLNLAGQLIMMQRDRSGPQIREKDSNPNNQ---------------RKLLPFCPPVVLAQSVENVWTTC--RANKQKRHLLE-----------ALWLSCGGAGMKVWLPLFPR-------DHRKPHSFLSQRIMLPFHI-NIYPLAVLFEDALVLGAVNDTLLYDSLYTRNNAREQLEVLFPFCVVERTSQIYLHHILRQLLVRNLGEQALLLAQSCATLPYFPHVLELMLHEVLEEEATSREPIPDPLLPTVAKFITEFPLFLQTVVHCARKTEYALWNYLFAAVGNPKDLFEECLMAQDLDTAASYLIILQNMEVPAVSRQHATLLFNTALEQGKWDLCRHMIRFLKAI 948
BLAST of RIC1 domain-containing protein vs. Ensembl Human
Match: RIC1 (RIC1 homolog, RAB6A GEF complex partner 1 [Source:HGNC Symbol;Acc:HGNC:17686]) HSP 1 Score: 488.034 bits (1255), Expect = 1.912e-147 Identity = 321/931 (34.48%), Postives = 490/931 (52.63%), Query Frame = 3
Query: 231 EWNSDGSLIAIGTDKGFLLIFSVKT----------VSQEVNVGYQNEKEFLEEGFINRQLSLFGEIILLDVISFPYKISCICLYRDDLLVAIEDGTLSRIKWNGSLLYNQEFNLTSISFFSDLEFSK-ASNLSKNEAICRNIEWLPSLSGVIVLFKNGKSAFLHIPNHKLLSEQITGVWAENLRNVTCSAVNVKFRSIAYGLKIGEAVIYKTDEETGALRLQHRLKILSNEYPDADKVTGAVTYLKWSPDNFCLALCWEYIGFSLWSVQGSLLFSSLGNKAGI--------DMSLLSLDWGCEGYSLWLI----------EKPDKS--GKPAILIFQMAKSVLVVNPTKNNHEHXXXXXXXHIIFG---------PRKLLSSSETNLEYIPYPENYVTWNWPIKYAAIDLNGSRLVISGKHGFALYF---FVSKKWRLFGNETQERTIEVSGGIVWYNHIVGLACFDNKEGKFEIRLYDSLQKIDNSLSTNHPVNSQILLMNIFDNTLVVLSIDGSIGLFEITLNEKSHDIS--MEYIQTIPLENYIEFAACIVSFNLSSLHTEIGHNKDVDELIR-YQSLLINYSGHLLLFQRDKSFSAPRTSDKSLNSQENSFFKLAFKNTLIAKQKITFTGPLVVAYNVEIMWTPIIDEEFQSKRLKLDDWNAKIYTMENSLWLNCGSQGLRVWLPLNGGSNVTQVGEKKSKYSFLSKRIMLTFKIRNFYPLVVLNNEALLMSPMNE-------FSNDFVNTPTCLNLSFSSINKNRHIFLQHIVKELLRINLGIHALDLTFELKKLPYFNHSXXXXXXXXXXXXATSKEPIPDPLLPRVVAFIQEFPNFLRTVVQCARKTELALWSYLFESAGNPKDLFESCLMNNELDTAASYLIILQNIEHPLISQKQAILLLDAALNRSNWGLVSNLIRFLKNI 2864
EW D ++IA+ T G++L F + + V + + + F EE Q + + + ++ I + +DLLVA DG L I W G + NL ++ F DL+ S+ S L + R++E+ +L G V+F +GK F+ + + +EQ+ GVW +++ + TC AVN K+R +A+G G +Y D TGA+ L H+L++ + +YPD TGAV ++WSPDN + + WEY G SLWSV G+ L +LG + + S+ WG EGY LW+I E +S +P+IL+FQ KSVL VNP +N E +LL + PR SS T+ E+ P E P ++ G ++ +H + ++ W + +E+ + V+GG+ W+N + LAC++ + + E+R+Y +DN+ + ++ LL+++F + ++V D SI L+ I + + ++ +Q + + YI +VS L+S+ TE G + + R +S+++N +G L++ QRD+S R D + N+Q ++ + F P+V+A +VE +WT + KR L+ +LWL+CG G++VWLPL + + +SFLS+RIML F I N YPL VL +AL++ +N+ ++ + + F + + I+L HI+++LL NLG AL L LPYF H LEL+LHEVLEEEATS+EPIPDPLLP V FI EFP FL+TVV CARKTE ALW+YLF + GNPKDLFE CLM +LDTAASYLIILQN+E P +S++ A LL + AL + W L ++IRFLK I
Sbjct: 2 EWRPDSTMIAVSTANGYILFFHITSTRGDKYLYEPVYPKGSPQMKGTPHFKEE-----QCAPALNLEMRKILDLQAPIMSLQSVLEDLLVATSDGLLHLIHWEGMTNGRKAINLCTVPFSVDLQSSRVGSFLGFTDVHIRDMEYCATLDGFAVVFNDGKVGFITPVSSRFTAEQLHGVWPQDVVDGTCVAVNNKYRLMAFGCVSGSVQVYTIDNSTGAMLLSHKLELTAKQYPDIWNKTGAVKLMRWSPDNSVVIVTWEYGGLSLWSVFGAQLICTLGGDFAYRSDGTKKDPLKINSMSWGAEGYHLWVISGFGSQNTEIESDLRSVVKQPSILLFQFIKSVLTVNPCMSNQEQVLLQGEDRLYLNCGEASQTQNPR----SSSTHSEHKPSREKS-----PFADGGLESQGLSTLLGHRHWHVVQISSTYLESNWPI-----REQNMIVTGGLAWWNDFMVLACYNINDRQEELRVYLRTSNLDNAFAHVTKAQAETLLLSVFQDMVIVFRADCSICLYSIERKSDGPNTTAGIQVLQEVSMSRYIPHPFLVVSVTLTSVSTENGITLKMPQQARGAESIMLNLAGQLIMMQRDRSGPQIREKDSNPNNQ---------------RKLLPFCPPVVLAQSVENVWTTC--RANKQKRHLLE-----------ALWLSCGGAGMKVWLPLFPR-------DHRKPHSFLSQRIMLPFHI-NIYPLAVLFEDALVLGAVNDTLLYDSLYTRNNAREQLEVLFPFCVVERTSQIYLHHILRQLLVRNLGEQALLLAQSCATLPYFPHVLELMLHEVLEEEATSREPIPDPLLPTVAKFITEFPLFLQTVVHCARKTEYALWNYLFAAVGNPKDLFEECLMAQDLDTAASYLIILQNMEVPAVSRQHATLLFNTALEQGKWDLCRHMIRFLKAI 877
BLAST of RIC1 domain-containing protein vs. Ensembl Human
Match: RIC1 (RIC1 homolog, RAB6A GEF complex partner 1 [Source:HGNC Symbol;Acc:HGNC:17686]) HSP 1 Score: 154.066 bits (388), Expect = 3.079e-42 Identity = 87/131 (66.41%), Postives = 99/131 (75.57%), Query Frame = 3
Query: 2358 FSSINKNRHIFLQHIVKELLRINLGIHALDLTFELKKLPYFNHSXXXXXXXXXXXXATSKEPIPDPLLPRVVAFIQEFPNFLRTVVQCARKTELALWSYLFESAGNPKDLFESCLMNNELDTAASYLIILQ 2750
F + + I+L HI+++LL NLG AL L LPYF H LEL+LHEVLEEEATS+EPIPDPLLP V FI EFP FL+TVV CARKTE ALW+YLF + GNPKDLFE CLM +LDTAASYLIILQ
Sbjct: 28 FCVVERTSQIYLHHILRQLLVRNLGEQALLLAQSCATLPYFPHVLELMLHEVLEEEATSREPIPDPLLPTVAKFITEFPLFLQTVVHCARKTEYALWNYLFAAVGNPKDLFEECLMAQDLDTAASYLIILQ 158
BLAST of RIC1 domain-containing protein vs. Ensembl Celegans
Match: R06F6.8 (Guanine nucleotide exchange factor subunit R06F6.8 [Source:UniProtKB/Swiss-Prot;Acc:Q09417]) HSP 1 Score: 375.17 bits (962), Expect = 3.715e-107 Identity = 267/996 (26.81%), Postives = 466/996 (46.79%), Query Frame = 3
Query: 234 WNSDGSLIAIGTDKGFLLIFSVKTVSQEVNVGY---------QNEKEFLEEGFINRQLSLFGEIILLDVISFPYKISCICLYRDDLLVAIEDGTLSRIKWNGSLLYNQEFNLTSISFFSDLEFSKASNLSKNEAICRNIEWLPSLSGVIVLFKNGKSAFLHIPNHKLLSEQITGVWAENLRNVTCSAVNVKFRSIAYGLKIGEAVIYKTDEETGALRLQHRLKILSNEYPDADKVTGAVTYLKWSPDNFCLALCWEYIGFSLWSVQGSLLFSSLGNKAGIDMSLL----------SLDWGCEGYSLWLIEKPDKSGKPAILIFQ-MAKSVLVVNPTKNNHEHXXXXXXXHIIFGPRK----LLSSSETNLEYIPYPENYVTWNWPIKYAAIDLNGSRLVISGKHGFALYFFVSKKWRLFGNETQERTIEVSGGI-VWYNHIVGLACFDNKEGKFEIRLYDSLQKIDNSLSTNHPVNSQILLMNIFDNTLVVLSIDGSIGLFEITLN-EKSHD----ISMEYIQTIPLENYIEFAACIVSFNLSSLHTEIGHNKDVDELIRYQSLLINYSGHLLLFQRDKSFSAPRTSDKSLNSQENSFFKLAFKNTLIAKQKITFTGPLVVAYNVEIMW---------TPIIDEEFQSKRLKLDDWNAKIYT--------------------MENSLWLNCGSQGLRVWLPLNGGSNVTQVGEKKSKYSFLSKRIMLTFKIRNFYPLVVLNNEALLM---SPMNEFSNDFVNTPTCLNLSFSSINKNRHIFLQHIVKELLRINLGIHALDLTFELKKLPYFNHSXXXXXXXXXXXXATSKEPIPDPLLPRVVAFIQEFPNFLRTVVQCARKTELALWSYLFESAGNPKDLFESCLMNNELDTAASYLIILQNIEHPLISQKQAILLLDAALNRSNWGLVSNLIRFLKNI----VEEVFKYEHARNEFKMIEKGNYKSTKETYSSFNTKKRYRSGGGIGMATSRQYS 3023
W D + IA+ T++ +LI+++ E + +N E +G +R + I++++ P +C RD+ LV +++G + W G ++ + F +SI F D SK+ N++ + + P L G ++ +G+ A L + I GVWA N+++ TC VN KF I +G K G+ Y DE G+L R+ PD G V + + + W + + + +F+S G ++ ++ + +++WG EG+ LWL G L+ Q +S +P + + +L+S S ++ + + + ++I Y++ NWP++YA+ D N LV++G G A +++W++FGNETQE+ + V+GG+ +W + ++G+ K + Y Q++D+ ++ + + ++ + D+ V I I L+++T + E D +S E + I + + CIVS ++ L+ ++ ++L+N SG L+ TL + P+V+A VE MW T +++ K + + N I + + N+LW+ CG++G++VW+PL G E +F++KRIML F++ + YP+V+ + L M S + + N +++ +++N +F+ H++++LL+ NLG+ AL+L + LP+F H+LELLLH VLEEEATS EPIPDPLLPR VAFI EFP FL+TV CARKTELALW LF+ G+P LFE CL +L+ AAS++I+LQN+E +S QA L+ AL W + ++RF ++I ++ F+ + + + S S+ R+++G G ++S
Sbjct: 78 WKPDSTSIAVTTNQCKILIYNLDLRDDEQCYNFTDSADPYFQRNSPELFIKG--SRPTAHLHPTIIINLADIP---TCCVPSRDEFLVCLQNGFTHHVTWTGEIIASLSFRASSIPFSVDQLQSKSENITSKSTYIFDAVYAPLLGGFAIVLSDGQGALLTSNDPNFAPNAILGVWAPNMKDATCCDVNHKFLLILFGCKNGDVCAYNIDELNGSLVQSFRVAPKVTNGPDLTNRLGPVHRITALANGYGFGAIWSPLSGAHALPRLVAVFTSFGAQSFCNLEGVVEEDQNDRYTAIEWGPEGFQLWL-------GTENELMMQPFVRSASCSSPAMEHCDRAVLMSDSQVLISAARDREAEACAPHSVWDHITVTHEYLSSNWPLRYASTDRNYKHLVVAGDQGMAYCSLSNRRWKIFGNETQEKNLLVTGGVFIWNDDVIGVVGVAADTDKSHLSFYPISQRLDSRYASVVDLEHKSVMSVLRDDVCAVFDISAQITLYKLTAHLETGRDAFTKVSTEIVTVIRINEIVPHPTCIVSLQMTQLNLDVRGKLSPAFYSSIDTVLVNISGRLI--------------------------------TLSVNEDGKLHQPMVIASYVEKMWHDRCQVSQSTQSQNQDLPWKNHRRNGSNVSIQSVSTSTTSEPSSPMNQSCSSHLSNALWIACGAKGIKVWMPLVPGKRNLATQE----MTFIAKRIMLPFEL-DIYPIVISAKDCLAMGVESQLQHVARASRNQGQMESITMYGLHRNSEVFVHHLLRQLLKRNLGVFALELAGACRSLPHFTHALELLLHGVLEEEATSSEPIPDPLLPRCVAFIHEFPEFLKTVAHCARKTELALWRTLFDVTGSPNALFEECLQLKQLENAASFVIVLQNLETTEVSMDQAARLVKEALEEKKWTIAKEMVRFARSIGSEDIDAFFRTPPPSAKTSLSRRPTVSSPSADSSTEFVINRFQAGAAGGRLNKVRHS 1024
BLAST of RIC1 domain-containing protein vs. Ensembl Celegans
Match: R06F6.8 (Guanine nucleotide exchange factor subunit R06F6.8 [Source:UniProtKB/Swiss-Prot;Acc:Q09417]) HSP 1 Score: 374.015 bits (959), Expect = 1.150e-106 Identity = 261/942 (27.71%), Postives = 446/942 (47.35%), Query Frame = 3
Query: 234 WNSDGSLIAIGTDKGFLLIFSVKTVSQEVNVGY---------QNEKEFLEEGFINRQLSLFGEIILLDVISFPYKISCICLYRDDLLVAIEDGTLSRIKWNGSLLYNQEFNLTSISFFSDLEFSKASNLSKNEAICRNIEWLPSLSGVIVLFKNGKSAFLHIPNHKLLSEQITGVWAENLRNVTCSAVNVKFRSIAYGLKIGEAVIYKTDEETGALRLQHRLKILSNEYPDADKVTGAVTYLKWSPDNFCLALCWEYIGFSLWSVQGSLLFSSLGNKAGIDMSLL----------SLDWGCEGYSLWLIEKPDKSGKPAILIFQ-MAKSVLVVNPTKNNHEHXXXXXXXHIIFGPRK----LLSSSETNLEYIPYPENYVTWNWPIKYAAIDLNGSRLVISGKHGFALYFFVSKKWRLFGNETQERTIEVSGGI-VWYNHIVGLACFDNKEGKFEIRLYDSLQKIDNSLSTNHPVNSQILLMNIFDNTLVVLSIDGSIGLFEITLN-EKSHD----ISMEYIQTIPLENYIEFAACIVSFNLSSLHTEIGHNKDVDELIRYQSLLINYSGHLLLFQRDKSFSAPRTSDKSLNSQENSFFKLAFKNTLIAKQKITFTGPLVVAYNVEIMWTPI--IDEEFQSKRLKLDDWNAK---------------------------IYTMENSLWLNCGSQGLRVWLPLNGGSNVTQVGEKKSKYSFLSKRIMLTFKIRNFYPLVVLNNEALLM---SPMNEFSNDFVNTPTCLNLSFSSINKNRHIFLQHIVKELLRINLGIHALDLTFELKKLPYFNHSXXXXXXXXXXXXATSKEPIPDPLLPRVVAFIQEFPNFLRTVVQCARKTELALWSYLFESAGNPKDLFESCLMNNELDTAASYLIILQNIEHPLISQKQAILLLDAALNRSNWGLVSNLIRFLKNIVEE 2873
W D + IA+ T++ +LI+++ E + +N E +G +R + I++++ P +C RD+ LV +++G + W G ++ + F +SI F D SK+ N++ + + P L G ++ +G+ A L + I GVWA N+++ TC VN KF I +G K G+ Y DE G+L R+ PD G V + + + W + + + +F+S G ++ ++ + +++WG EG+ LWL G L+ Q +S +P + + +L+S S ++ + + + ++I Y++ NWP++YA+ D N LV++G G A +++W++FGNETQE+ + V+GG+ +W + ++G+ K + Y Q++D+ ++ + + ++ + D+ V I I L+++T + E D +S E + I + + CIVS ++ L+ ++ ++L+N SG L+ TL + P+V+A VE MW + + QS+ L N + + N+LW+ CG++G++VW+PL G E +F++KRIML F++ + YP+V+ + L M S + + N +++ +++N +F+ H++++LL+ NLG+ AL+L + LP+F H+LELLLH VLEEEATS EPIPDPLLPR VAFI EFP FL+TV CARKTELALW LF+ G+P LFE CL +L+ AAS++I+LQN+E +S QA L+ AL W + ++RF ++I E
Sbjct: 78 WKPDSTSIAVTTNQCKILIYNLDLRDDEQCYNFTDSADPYFQRNSPELFIKG--SRPTAHLHPTIIINLADIP---TCCVPSRDEFLVCLQNGFTHHVTWTGEIIASLSFRASSIPFSVDQLQSKSENITSKSTYIFDAVYAPLLGGFAIVLSDGQGALLTSNDPNFAPNAILGVWAPNMKDATCCDVNHKFLLILFGCKNGDVCAYNIDELNGSLVQSFRVAPKVTNGPDLTNRLGPVHRITALANGYGFGAIWSPLSGAHALPRLVAVFTSFGAQSFCNLEGVVEEDQNDRYTAIEWGPEGFQLWL-------GTENELMMQPFVRSASCSSPAMEHCDRAVLMSDSQVLISAARDREAEACAPHSVWDHITVTHEYLSSNWPLRYASTDRNYKHLVVAGDQGMAYCSLSNRRWKIFGNETQEKNLLVTGGVFIWNDDVIGVVGVAADTDKSHLSFYPISQRLDSRYASVVDLEHKSVMSVLRDDVCAVFDISAQITLYKLTAHLETGRDAFTKVSTEIVTVIRINEIVPHPTCIVSLQMTQLNLDVRGKLSPAFYSSIDTVLVNISGRLI--------------------------------TLSVNEDGKLHQPMVIASYVEKMWHDRCQVSQSTQSQNQDLPWKNHRRNGSNVSIQSVSTSTTSEPSSPMNQSCSSHLSNALWIACGAKGIKVWMPLVPGKRNLATQE----MTFIAKRIMLPFEL-DIYPIVISAKDCLAMGVESQLQHVARASRNQGQMESITMYGLHRNSEVFVHHLLRQLLKRNLGVFALELAGACRSLPHFTHALELLLHGVLEEEATSSEPIPDPLLPRCVAFIHEFPEFLKTVAHCARKTELALWRTLFDVTGSPNALFEECLQLKQLENAASFVIVLQNLETTEVSMDQAARLVKEALEEKKWTIAKEMVRFARSIGSE 970
BLAST of RIC1 domain-containing protein vs. Ensembl Fly
Match: Rich (gene:FBgn0028500 transcript:FBtr0078512) HSP 1 Score: 465.307 bits (1196), Expect = 1.330e-138 Identity = 326/1031 (31.62%), Postives = 516/1031 (50.05%), Query Frame = 3
Query: 21 MYYFFNCPKRIS----------RHFVPSNITGIISSKSFALCAIFNSSQIIVFENKNNSIVAYYCRCEESLDIYGNSINLEWNSDGSLIAIGTDKGFLLIFSVK------TVSQEVNVGYQNEKEFLEEGFINRQLSLFGEIILLDVISFPYKISCICLYRDDLLVAIEDGTLSRIKWNGSLLYNQEFNLTSISF--FSDLEF-------SKASNLSK--NEAICRNIEWLPSLSGVIVLFKNGKSAFLHIPNH-KLLSEQITGVWAENLRNVTCSAVNVKFRSIAYGLKIGEAVIYKTDEETGALRLQHRLKILSNEYPDADKVTGAVTYLKWSPDNFCLALCWEYIGFSLWSVQGSLLFSSLGNKAGIDMSLLS--------LDWGCEGYSLWLIEKPDKSGKPAILIFQMAKSVLVVNPTKNNHEH-----------------XXXXXXXHIIFGPRKLLSSSET--------NLEYIPY----------------PENYVTWNWPIKYAAIDLNGSRLVISGKHGFALYFFVSKKWRLFGNETQERTIEVSGGIVWYNHIVGLACFDNKEGKFEIRLYDSLQKIDNSLSTNHPVNSQILLMNIFDNTLVVLSIDGSIGLFEITLNEKSHDISMEYIQTIPLENYIEFAACIVSFNLSSLHTEIGHNKDVDELIRYQSLLINYSGHLLLFQRDKSFSAPRTSDKSLNSQENSFFKLAFKNTLIAKQKITFTGPLVVAYNVEIMWTPIIDEEFQSKRLKLDDWNAKIYTMENSLWLNCGSQGLRVWLPLNGGSNVTQVGEKKSK---YSFLSKRIMLTFKIRNFYPLVVLNNEALLMSPMNE---FSNDFVNTPTCLNLSFSSINKNRHIFLQHIVKELLRINLGIHALDLTFELKKLPYFNHSXXXXXXXXXXXXATSKEPIPDPLLPRVVAFIQEFPNFLRTVVQCARKTELALWSYLFESAGNPKDLFESCLMNNELDTAASYLIILQNIEHPLISQKQAILLLDAALNRSNWGLVSNLIRFLKNI 2864
MYY PKR+ RH + ++++ I+ ++ +I +AY+ R E+SL YG + + W D +A+ T G LL++ + + Q+++ + K E FI + L V + C+ +LL+A + L R++W + L ++S D+ F A N+ ++ ++E+ P + G +F + ++AFL I NH + ++ + G W ++ + + +VN KFR +AYG + +Y D+ TG L HRL + N PD+ G+V LKWSPD LA+ W G SLWS G+LL S+L G+++ L+ L+W EGY L++++ + K +L Q KS L +NP H L + SH F P L S E L+ P+ P NY NWPI+YAAID +G L ++G+ G A Y V+++W+LFGNE+QE+ VSGG++W++ V + C+ + E+R Y + K+DN V + ++ +N F + L+VL+ DG + LF ++ N ++ + +E + +++ ACIVS +++L E+ + + +++++N G +L+ QRD P NTL+A +A VE+ W + + M + LWL G+ G+RVWLP+ + GE+ +SF+SKRIML+F ++ YPLVVL + +++ NE ++N+ V+ +L F+ + + I+L ++++L++ NLG A ++ LPYF H+LELLLHEVLEEEATSK+PIPD LP ++ FI+EFP +L T+VQCARKTE+ALW YLF AG PKDLF+ CL + +LDTAASYLIILQN+E ++S++ A +LLD AL + W L +LIRFLK I
Sbjct: 1 MYYPVGWPKRVGLALPGESASIRHICCDAVKILVAAVGDDFLGIWYANPLIP--------IAYFRRTEDSLRQYGANQLIVWKPDSRQLALLTASGSLLLYQLDFEANGMGILQQIDPPAASLKRDSAELFIKENIPRLSLRELCSVTLGSVITTVCCISLSELLLATQSCELLRLQWTELEHAENDLELPALSSIKLRDIPFYVQQQPQQSARNVPPLNRDSYVASLEYSPFIGGCAAVFSDRRAAFL-IANHLRFETDHMHGFWVPDVEDASVCSVNHKFRLLAYGQESSAVKVYAIDDATGGLEFSHRLILTENILPDS---LGSVNELKWSPDGCVLAVSWTNGGLSLWSTFGALLMSTLSWDFGLNVDLVCQNPLKIRRLEWSTEGYQLFMLKLHPEKDKSNVLQLQFVKSALSMNPCMTTSPHILLQGDDCLYLNQGNNLELTYAGSHGTF-PSSGLGSDEDISGDGDCLELKQSPHTGSILTESKYWTVLQLPLNYAATNWPIRYAAIDPDGLHLAVAGRTGLAHYSLVTRRWKLFGNESQEKDFVVSGGLLWWHGFVVMGCYSLLDRTDELRCYPADCKLDNQYGHKLQVRAPVISLNSFRHQLIVLTADGIVSLFNMSKN-SAYALDIECAYELDVKSICIHPACIVSLTVTNLKNELKPQGQLGG-DQAETIIVNVCGRILMIQRDAGEQVP--------------------NTLLAT---------CLASCVEVFWL---------------SHSLERCAMRDCLWLYSGAHGMRVWLPILPPGRERREGEQGGAQRLHSFMSKRIMLSFPLK-LYPLVVLFDNVIVLGVENESTLYANEQVSH---FSLPFAVMERKSQIYLHKVLRQLIKRNLGYSAWEMAQSCCSLPYFPHALELLLHEVLEEEATSKQPIPDAQLPSILDFIREFPVYLETIVQCARKTEIALWPYLFSMAGKPKDLFQMCLQSEQLDTAASYLIILQNLEPSVVSKQYATMLLDIALQQRKWELAKDLIRFLKAI 968
BLAST of RIC1 domain-containing protein vs. Ensembl Fly
Match: Rich (gene:FBgn0028500 transcript:FBtr0334751) HSP 1 Score: 465.307 bits (1196), Expect = 1.330e-138 Identity = 326/1031 (31.62%), Postives = 516/1031 (50.05%), Query Frame = 3
Query: 21 MYYFFNCPKRIS----------RHFVPSNITGIISSKSFALCAIFNSSQIIVFENKNNSIVAYYCRCEESLDIYGNSINLEWNSDGSLIAIGTDKGFLLIFSVK------TVSQEVNVGYQNEKEFLEEGFINRQLSLFGEIILLDVISFPYKISCICLYRDDLLVAIEDGTLSRIKWNGSLLYNQEFNLTSISF--FSDLEF-------SKASNLSK--NEAICRNIEWLPSLSGVIVLFKNGKSAFLHIPNH-KLLSEQITGVWAENLRNVTCSAVNVKFRSIAYGLKIGEAVIYKTDEETGALRLQHRLKILSNEYPDADKVTGAVTYLKWSPDNFCLALCWEYIGFSLWSVQGSLLFSSLGNKAGIDMSLLS--------LDWGCEGYSLWLIEKPDKSGKPAILIFQMAKSVLVVNPTKNNHEH-----------------XXXXXXXHIIFGPRKLLSSSET--------NLEYIPY----------------PENYVTWNWPIKYAAIDLNGSRLVISGKHGFALYFFVSKKWRLFGNETQERTIEVSGGIVWYNHIVGLACFDNKEGKFEIRLYDSLQKIDNSLSTNHPVNSQILLMNIFDNTLVVLSIDGSIGLFEITLNEKSHDISMEYIQTIPLENYIEFAACIVSFNLSSLHTEIGHNKDVDELIRYQSLLINYSGHLLLFQRDKSFSAPRTSDKSLNSQENSFFKLAFKNTLIAKQKITFTGPLVVAYNVEIMWTPIIDEEFQSKRLKLDDWNAKIYTMENSLWLNCGSQGLRVWLPLNGGSNVTQVGEKKSK---YSFLSKRIMLTFKIRNFYPLVVLNNEALLMSPMNE---FSNDFVNTPTCLNLSFSSINKNRHIFLQHIVKELLRINLGIHALDLTFELKKLPYFNHSXXXXXXXXXXXXATSKEPIPDPLLPRVVAFIQEFPNFLRTVVQCARKTELALWSYLFESAGNPKDLFESCLMNNELDTAASYLIILQNIEHPLISQKQAILLLDAALNRSNWGLVSNLIRFLKNI 2864
MYY PKR+ RH + ++++ I+ ++ +I +AY+ R E+SL YG + + W D +A+ T G LL++ + + Q+++ + K E FI + L V + C+ +LL+A + L R++W + L ++S D+ F A N+ ++ ++E+ P + G +F + ++AFL I NH + ++ + G W ++ + + +VN KFR +AYG + +Y D+ TG L HRL + N PD+ G+V LKWSPD LA+ W G SLWS G+LL S+L G+++ L+ L+W EGY L++++ + K +L Q KS L +NP H L + SH F P L S E L+ P+ P NY NWPI+YAAID +G L ++G+ G A Y V+++W+LFGNE+QE+ VSGG++W++ V + C+ + E+R Y + K+DN V + ++ +N F + L+VL+ DG + LF ++ N ++ + +E + +++ ACIVS +++L E+ + + +++++N G +L+ QRD P NTL+A +A VE+ W + + M + LWL G+ G+RVWLP+ + GE+ +SF+SKRIML+F ++ YPLVVL + +++ NE ++N+ V+ +L F+ + + I+L ++++L++ NLG A ++ LPYF H+LELLLHEVLEEEATSK+PIPD LP ++ FI+EFP +L T+VQCARKTE+ALW YLF AG PKDLF+ CL + +LDTAASYLIILQN+E ++S++ A +LLD AL + W L +LIRFLK I
Sbjct: 1 MYYPVGWPKRVGLALPGESASIRHICCDAVKILVAAVGDDFLGIWYANPLIP--------IAYFRRTEDSLRQYGANQLIVWKPDSRQLALLTASGSLLLYQLDFEANGMGILQQIDPPAASLKRDSAELFIKENIPRLSLRELCSVTLGSVITTVCCISLSELLLATQSCELLRLQWTELEHAENDLELPALSSIKLRDIPFYVQQQPQQSARNVPPLNRDSYVASLEYSPFIGGCAAVFSDRRAAFL-IANHLRFETDHMHGFWVPDVEDASVCSVNHKFRLLAYGQESSAVKVYAIDDATGGLEFSHRLILTENILPDS---LGSVNELKWSPDGCVLAVSWTNGGLSLWSTFGALLMSTLSWDFGLNVDLVCQNPLKIRRLEWSTEGYQLFMLKLHPEKDKSNVLQLQFVKSALSMNPCMTTSPHILLQGDDCLYLNQGNNLELTYAGSHGTF-PSSGLGSDEDISGDGDCLELKQSPHTGSILTESKYWTVLQLPLNYAATNWPIRYAAIDPDGLHLAVAGRTGLAHYSLVTRRWKLFGNESQEKDFVVSGGLLWWHGFVVMGCYSLLDRTDELRCYPADCKLDNQYGHKLQVRAPVISLNSFRHQLIVLTADGIVSLFNMSKN-SAYALDIECAYELDVKSICIHPACIVSLTVTNLKNELKPQGQLGG-DQAETIIVNVCGRILMIQRDAGEQVP--------------------NTLLAT---------CLASCVEVFWL---------------SHSLERCAMRDCLWLYSGAHGMRVWLPILPPGRERREGEQGGAQRLHSFMSKRIMLSFPLK-LYPLVVLFDNVIVLGVENESTLYANEQVSH---FSLPFAVMERKSQIYLHKVLRQLIKRNLGYSAWEMAQSCCSLPYFPHALELLLHEVLEEEATSKQPIPDAQLPSILDFIREFPVYLETIVQCARKTEIALWPYLFSMAGKPKDLFQMCLQSEQLDTAASYLIILQNLEPSVVSKQYATMLLDIALQQRKWELAKDLIRFLKAI 968
BLAST of RIC1 domain-containing protein vs. Ensembl Zebrafish
Match: RIC1 (RIC1 homolog, RAB6A GEF complex partner 1 [Source:HGNC Symbol;Acc:HGNC:17686]) HSP 1 Score: 477.633 bits (1228), Expect = 7.855e-144 Identity = 324/982 (32.99%), Postives = 501/982 (51.02%), Query Frame = 3
Query: 93 SSKSFALCAIFNSSQIIVFENKNNSIVAYYCRCEESLDIYGNSINLEWNSDGSLIAIGTDKGFLLIFSVKTVSQEVNVGYQNEKEFLEE-------------GFINRQLSLFGEIILLDVISFPYKISCICLYRDDLLVAIEDGTLSRIKWNGSLLYNQEFNLTSISFFSDLEFSKASN-LSKNEAICRNIEWLPSLSGVIVLFKNGKSAFLHIPNHKLLSEQITGVWAENLRNVTCSAVNVKFRSIAYGLKIGEAVIYKTDEETGALRLQHRLKILSNEYPDADKVTGAVTYLKWSPDNFCLALCWEYIGFSLWSVQGSLLFSSLGNKAGI--------DMSLLSLDWGCEGYSLWLI---------EKPDKSGKPAILIFQMAKS---------------VLVVNPTKNNHE-HXXXXXXXHIIFGPRKLLSSSETNLEYIPYPENYVTWNWPIKYA-AIDLNGSRLVISGKHGFALYFFVSKKWRLFGNETQERTIEVSGGIVWYNHIVGLACFDNKEGKFEIRLYDSLQKIDNSLSTNHPVNSQILLMNIFDNTLVVLSIDGSIGLFEITLNEKSHD-----ISMEYIQTIPLENYIEFAACIVSFNLSSLHTEIGHN-KDVDELIRYQSLLINYSGHLLLFQRDKSFSAPRTSDKSLNSQENSFFKLAFKNTLIAKQKITFTGPLVVAYNVEIMWTPIIDEEFQSKRLKLDDWNAKIYTMENSLWLNCGSQGLRVWLPLNGGSNVTQVGEKKSKYSFLSKRIMLTFKIRNFYPLVVLNNEALLMSPMNE--FSNDFVNTPTCLN--LSFSSINKNRHIFLQHIVKELLRINLGIHALDLTFELKKLPYFNHSXXXXXXXXXXXXATSKEPIPDPLLPRVVAFIQEFPNFLRTVVQCARKTELALWSYLFESAGNPKDLFESCLMNNELDTAASYLIILQNIEHPLISQKQAILLLDAALNRSNWGLVSNLIRFLKNI 2864
S++ F L A+ + +QI ++ ++ + ++ Y ++ +G +EW D S+IA+ G++L+F + +G ++K E G+ Q + + + + ISC+ +DLLVA DG L + W+ + NL +I F DL+ S+ L + R++E+ +L G V+F +G+ F+ ++L ++Q+ GVWA ++ + TC AVN K+R +A+G G ++Y D TG ++L H+L++ YPD TG V ++WSPD + WE G SLWSV G+ L +LG + + S+ WG EGY LW+I EK +K + IL FQ KS V +PT+ S++ + G LL + + + Y+ NWPI+ A D L++ ++ + + E+ + V+GG+ W+N V +AC++ + + E+RLY +DN+ ++ +++ LL+N+F N +++ D SI L+ I E+ HD S+E +Q + + YI +VS L+S+ TE G K + +S+L+N +G L++ QRD+S R D N + + F P+V+A VE +WT S R N K + +LWL+CG G++VWLPL + + +SFLS+RIML F I N YPL VL +AL++ NE + ++ L + ++ + I+L HI+++LL NLG AL L LPYF H LEL++H VLEEEATS+EPIPDPLLP V F+ EFP FL+T+V CARKTE ALW+YLF + GNPKDLFE CLM +LDTAASYLIILQN+E P +S++ A LL + AL + W L ++IRFLK I
Sbjct: 27 SAQRFYL-AVLSETQISIWFSRPSVLIVSYIESGKAAAQFGFYQQVEWKPDDSMIAVAAANGYVLLFDI--------IGGLDDKYLYEPVYPKGSARVKVTPGYKEEQCAPALTLEMKKPVDLEAPISCLQSLAEDLLVATADGFLHMLHWDSVSNGRRAVNLCTIPFSLDLQSSRGGPCLDLDGVYIRDLEYCATLDGFAVVFDDGRIGFITPTANRLATDQLQGVWAADVTDGTCVAVNNKYRLMAFGCTSGSVLVYMIDSSTGCMQLSHKLELTPKHYPDIWNKTGPVKMIRWSPDCSVAMVTWECGGLSLWSVFGAHLICTLGEDFAYRSDGTKKDPLKISSMSWGVEGYHLWVIRSSDSTVTEEKQEKLQQNTILQFQFIKSSNQEQVLLQGEDRLYVTCGDPTQTQTPGQCRSSSTAPLSQGLSTLLG--HKHWQVVQIHSTYLETNWPIRVRNAHDRRRVTLIM---------LMLTDHYAVC-----EQNMTVTGGLAWWNDFVVVACYNFIDRQEELRLYVRSANLDNAFASITKLHADTLLLNVFRNMVILFRADCSICLYSI---ERRHDGPSPSASVELLQEVSMSRYIPHPGLVVSVTLTSVRTESGITLKAPQQACSAESILLNLAGQLIMLQRDRSGPQVREKDAPANH----------------SKLLPFCPPVVLAQCVESVWT--------SSRS-----NRKKRHLMEALWLSCGEAGMKVWLPLFPR-------DHRKPHSFLSRRIMLPFHI-NIYPLTVLFEDALILGASNETVLFDGLSSSAEPLEALFPYCTVERTSQIYLHHILRQLLVRNLGEQALMLAQSCASLPYFPHVLELMVHVVLEEEATSREPIPDPLLPTVAKFVTEFPLFLQTIVHCARKTEYALWNYLFAAVGNPKDLFEECLMAQDLDTAASYLIILQNMEVPAVSRQHATLLFNTALEQGKWDLCRHMIRFLKAI 943
BLAST of RIC1 domain-containing protein vs. Ensembl Xenopus
Match: nsun3 (NOP2/Sun RNA methyltransferase family member 3 [Source:Xenbase;Acc:XB-GENE-980505]) HSP 1 Score: 545.428 bits (1404), Expect = 1.787e-167 Identity = 367/1079 (34.01%), Postives = 563/1079 (52.18%), Query Frame = 3
Query: 117 AIFNSSQIIVFENKNNSIVAYYCRCEESLDIYGNSINLEWNSDGSLIAIGTDKGFLLIFSVKTVSQEVNVGYQNEKEF--------LEEGFINRQLSLFGEIILLDVISFPYKISCICLYRDDLLVAIEDGTLSRIKWNGSLLYNQEFNLTSISFFSDLEFSKASN-LSKNEAICRNIEWLPSLSGVIVLFKNGKSAFLHIPNHKLLSEQITGVWAENLRNVTCSAVNVKFRSIAYGLKIGEAVIYKTDEETGALRLQHRLKILSNEYPDADKVTGAVTYLKWSPDNFCLALCWEYIGFSLWSVQGSLLFSSLGNKAGID--------MSLLSLDWGCEGYSLWLI----------EKPDKS--GKPAILIFQMAKSVLVVNPTKNNHEHXXXXXXXHIIFG---------PRKLLSSSETN--LEYIPYP------------------------ENYVTWNWPIKYAAIDLNGSRLVISGKHGFALYFFVSKKWRLFGNETQERTIEVSGGIVWYNHIVGLACFDNKEGKFEIRLYDSLQKIDNSLSTNHPVNSQILLMNIFDNTLVVLSIDGSIGLFEITLNEKSHD--ISMEYIQTIPLENYIEFAACIVSFNLSSLHTEIGHN-KDVDELIRYQSLLINYSGHLLLFQRDKSFSAPRTSDKSLNSQENSFFKLAFKNTLIAKQKITFTGPLVVAYNVEIMWTPIIDEEFQSKRLKLDDWNAKIYTMENSLWLNCGSQGLRVWLPLNGGSNVTQVGEKKSKYSFLSKRIMLTFKIRNFYPLVVLNNEALLMSPMNE-FSNDFVNTPTC------LNLSFSSINKNRHIFLQHIVKELLRINLGIHALDLTFELKKLPYFNHSXXXXXXXXXXXXATSKEPIPDPLLPRVVAFIQEFPNFLRTVVQCARKTELALWSYLFESAGNPKDLFESCLMNNELDTAASYLIILQNIEHPLISQKQAILLLDAALNRSNWGLVSNLIRFLKNIVEEVFKYEHARNEFKMIEKGNYKSTKETYSSFNTK-KRYRSGGGIGMATSRQ-YSTGK--IKDIEILKSSKSAQNGNIDENCYDDLVFD 3119
++ + +Q+ ++ ++ + ++A Y ++ +GN EW D S+I I T G++L F + V ++ Y E + L + Q + + V+ I+ I +DLLVA EDG L I W G + NLT+I F D + S+A + L + R++E+ +L G V+F +G+ F+ +++L ++QI GVWA ++ + TC AVN K+R +A+G G +++ D TGAL+L H+L++ +YPD TGAV ++WSPD + + WE G SLWSV G+ L +LG + + S+ WG EGY LW I E DKS + IL FQ KS L VNP +N E +LL + R S SE + P+P Y+ NWPI+Y AID G + + GK GFA Y ++KKW+LFGN TQE+ + VSGG+ W+ + LACF+ E + E+R+Y +DN+ + V + LL++IF + +++ D SI L+ I ++ + + ++ +Q + + YI + +VS L+S+ TE G + K + +S+L+N +G L++ QRD+S P+ +K + ++ + F P+V+A +VE +W+ + KR L+ +LWL+CG G++VWLPL + + +SFLSKRIML F I N YPL VL +AL++ +NE + D +N + ++ F + + I+L HI+++LL NLG AL L LPYF H LEL+LHEVLEEEATS+EPIPDPLLP V FI EFP FL+TVV CARKTE ALW+YLF + GNPKDLFE CLM +L+TAASYLIILQN+E +S++ A LL + AL + W L ++IRFLK I +M +T+E S+ + R+RS I ++ S + + +GK ++ + S + + + D +C +++ D
Sbjct: 34 SVLSQTQLSIWYSRPSVLIASYKESAKATAQFGNYKQAEWRPDSSMIVIATANGYILFFDIIPVGED---KYLYEPVYPKGSPHIKLNPHYKEEQCAPALNLETKKVMDLQASITSIQSMMEDLLVATEDGLLHIIHWEGMTNGRKAINLTTIPFSIDFQPSRAGSFLDFGDVHIRDMEYCATLDGFAVVFNDGRVGFITPGSNRLTADQIHGVWAPDVVDGTCVAVNNKYRLMAFGCVGGSVLVFTIDNTTGALQLSHKLELTPKQYPDMWNKTGAVKLIRWSPDCSVVMVTWECGGLSLWSVFGAHLICTLGGDFDYRADGTKKEALRICSMSWGTEGYHLWAITADSSQNTGYEMSDKSVPQQSGILQFQFIKSALTVNPCMSNQEQVLLQGEDRLYLNCGDATQTQNARNGSSQSEHKPLRDRSPFPGSSGNSQGLSTLLGHRHWHVVQIQSTYLQSNWPIRYTAIDKVGQNVAVVGKFGFAHYSLLTKKWKLFGNITQEQNMVVSGGLSWWKEFIVLACFNLSEQQEELRVYLRTSNLDNAFAHVIKVQLETLLLSIFRDMVIIFRADCSICLYSIERKKEGPNPSVCLQVLQEVSMSRYIPHPSLVVSVTLTSVRTETGISLKMPQQACDAESILLNLAGQLIMLQRDRS--GPQIREKDAKTHQHKL--------------LPFCAPVVLAQSVENVWSTC--RANKQKRHLLE-----------ALWLSCGGAGMKVWLPLFPR-------DHRKPHSFLSKRIMLPFHI-NIYPLAVLFEDALVLGAINETVAYDCLNNLSTSSEHLEVHFPFCIVERTSQIYLHHILRQLLVRNLGEQALLLAQSCAALPYFPHVLELMLHEVLEEEATSREPIPDPLLPTVAKFITEFPLFLQTVVHCARKTEYALWNYLFAAVGNPKDLFEECLMAQDLETAASYLIILQNMEAAAVSRQHATLLFNTALEQGKWDLCRHMIRFLKAI-----------GSGEMETPPATPTTQEPSSTGGFEFFRHRS---ISLSQSAENFPSGKFNLQKTHSMPSGAAGKRWSKDSDCAENMYID 1058
BLAST of RIC1 domain-containing protein vs. Ensembl Xenopus
Match: nsun3 (NOP2/Sun RNA methyltransferase family member 3 [Source:Xenbase;Acc:XB-GENE-980505]) HSP 1 Score: 540.421 bits (1391), Expect = 5.619e-166 Identity = 364/1071 (33.99%), Postives = 556/1071 (51.91%), Query Frame = 3
Query: 117 AIFNSSQIIVFENKNNSIVAYYCRCEESLDIYGNSINLEWNSDGSLIAIGTDKGFLLIFSVKTVSQEVNVGYQNEKEFLEEGFINRQLSLFGEIILLDVISFPYKISCICLYRDDLLVAIEDGTLSRIKWNGSLLYNQEFNLTSISFFSDLEFSKASN-LSKNEAICRNIEWLPSLSGVIVLFKNGKSAFLHIPNHKLLSEQITGVWAENLRNVTCSAVNVKFRSIAYGLKIGEAVIYKTDEETGALRLQHRLKILSNEYPDADKVTGAVTYLKWSPDNFCLALCWEYIGFSLWSVQGSLLFSSLGNKAGID--------MSLLSLDWGCEGYSLWLI----------EKPDKS--GKPAILIFQMAKSVLVVNPTKNNHEHXXXXXXXHIIFG---------PRKLLSSSETN--LEYIPYP------------------------ENYVTWNWPIKYAAIDLNGSRLVISGKHGFALYFFVSKKWRLFGNETQERTIEVSGGIVWYNHIVGLACFDNKEGKFEIRLYDSLQKIDNSLSTNHPVNSQILLMNIFDNTLVVLSIDGSIGLFEITLNEKSHD--ISMEYIQTIPLENYIEFAACIVSFNLSSLHTEIGHN-KDVDELIRYQSLLINYSGHLLLFQRDKSFSAPRTSDKSLNSQENSFFKLAFKNTLIAKQKITFTGPLVVAYNVEIMWTPIIDEEFQSKRLKLDDWNAKIYTMENSLWLNCGSQGLRVWLPLNGGSNVTQVGEKKSKYSFLSKRIMLTFKIRNFYPLVVLNNEALLMSPMNE-FSNDFVNTPTC------LNLSFSSINKNRHIFLQHIVKELLRINLGIHALDLTFELKKLPYFNHSXXXXXXXXXXXXATSKEPIPDPLLPRVVAFIQEFPNFLRTVVQCARKTELALWSYLFESAGNPKDLFESCLMNNELDTAASYLIILQNIEHPLISQKQAILLLDAALNRSNWGLVSNLIRFLKNIVEEVFKYEHARNEFKMIEKGNYKSTKETYSSFNTK-KRYRSGGGIGMATSRQ-YSTGK--IKDIEILKSSKSAQNGNIDENCYDDLVFD 3119
++ + +Q+ ++ ++ + ++A Y ++ +GN EW D S+I I T G++L F + V ++ K E + N Q + +DLLVA EDG L I W G + NLT+I F D + S+A + L + R++E+ +L G V+F +G+ F+ +++L ++QI GVWA ++ + TC AVN K+R +A+G G +++ D TGAL+L H+L++ +YPD TGAV ++WSPD + + WE G SLWSV G+ L +LG + + S+ WG EGY LW I E DKS + IL FQ KS L VNP +N E +LL + R S SE + P+P Y+ NWPI+Y AID G + + GK GFA Y ++KKW+LFGN TQE+ + VSGG+ W+ + LACF+ E + E+R+Y +DN+ + V + LL++IF + +++ D SI L+ I ++ + + ++ +Q + + YI + +VS L+S+ TE G + K + +S+L+N +G L++ QRD+S P+ +K + ++ + F P+V+A +VE +W+ + KR L+ +LWL+CG G++VWLPL + + +SFLSKRIML F I N YPL VL +AL++ +NE + D +N + ++ F + + I+L HI+++LL NLG AL L LPYF H LEL+LHEVLEEEATS+EPIPDPLLP V FI EFP FL+TVV CARKTE ALW+YLF + GNPKDLFE CLM +L+TAASYLIILQN+E +S++ A LL + AL + W L ++IRFLK I +M +T+E S+ + R+RS I ++ S + + +GK ++ + S + + + D +C +++ D
Sbjct: 34 SVLSQTQLSIWYSRPSVLIASYKESAKATAQFGNYKQAEWRPDSSMIVIATANGYILFFDIIPVGED--------KYLYEPVYPNIQSMM-----------------------EDLLVATEDGLLHIIHWEGMTNGRKAINLTTIPFSIDFQPSRAGSFLDFGDVHIRDMEYCATLDGFAVVFNDGRVGFITPGSNRLTADQIHGVWAPDVVDGTCVAVNNKYRLMAFGCVGGSVLVFTIDNTTGALQLSHKLELTPKQYPDMWNKTGAVKLIRWSPDCSVVMVTWECGGLSLWSVFGAHLICTLGGDFDYRADGTKKEALRICSMSWGTEGYHLWAITADSSQNTGYEMSDKSVPQQSGILQFQFIKSALTVNPCMSNQEQVLLQGEDRLYLNCGDATQTQNARNGSSQSEHKPLRDRSPFPGSSGNSQGLSTLLGHRHWHVVQIQSTYLQSNWPIRYTAIDKVGQNVAVVGKFGFAHYSLLTKKWKLFGNITQEQNMVVSGGLSWWKEFIVLACFNLSEQQEELRVYLRTSNLDNAFAHVIKVQLETLLLSIFRDMVIIFRADCSICLYSIERKKEGPNPSVCLQVLQEVSMSRYIPHPSLVVSVTLTSVRTETGISLKMPQQACDAESILLNLAGQLIMLQRDRS--GPQIREKDAKTHQHKL--------------LPFCAPVVLAQSVENVWSTC--RANKQKRHLLE-----------ALWLSCGGAGMKVWLPLFPR-------DHRKPHSFLSKRIMLPFHI-NIYPLAVLFEDALVLGAINETVAYDCLNNLSTSSEHLEVHFPFCIVERTSQIYLHHILRQLLVRNLGEQALLLAQSCAALPYFPHVLELMLHEVLEEEATSREPIPDPLLPTVAKFITEFPLFLQTVVHCARKTEYALWNYLFAAVGNPKDLFEECLMAQDLETAASYLIILQNMEAAAVSRQHATLLFNTALEQGKWDLCRHMIRFLKAI-----------GSGEMETPPATPTTQEPSSTGGFEFFRHRS---ISLSQSAENFPSGKFNLQKTHSMPSGAAGKRWSKDSDCAENMYID 1022
BLAST of RIC1 domain-containing protein vs. Ensembl Xenopus
Match: nsun3 (NOP2/Sun RNA methyltransferase family member 3 [Source:Xenbase;Acc:XB-GENE-980505]) HSP 1 Score: 540.036 bits (1390), Expect = 1.617e-165 Identity = 367/1079 (34.01%), Postives = 563/1079 (52.18%), Query Frame = 3
Query: 117 AIFNSSQIIVFENKNNSIVAYYCRCEESLDIYGNSINLEWNSDGSLIAIGTDKGFLLIFSVKTVSQEVNVGYQNEKEF--------LEEGFINRQLSLFGEIILLDVISFPYKISCICLYRDDLLVAIEDGTLSRIKWNGSLLYNQEFNLTSISFFSDLEFSKASN-LSKNEAICRNIEWLPSLSGVIVLFKNGKSAFLHIPNHKLLSEQITGVWAENLRNVTCSAVNVKFRSIAYGLKIGEAVIYKTDEETGALRLQHRLKILSNEYPDADKVTGAVTYLKWSPDNFCLALCWEYIGFSLWSVQGSLLFSSLGNKAGID--------MSLLSLDWGCEGYSLWLI----------EKPDKS--GKPAILIFQMAKSVLVVNPTKNNHEHXXXXXXXHIIFG---------PRKLLSSSETN--LEYIPYP------------------------ENYVTWNWPIKYAAIDLNGSRLVISGKHGFALYFFVSKKWRLFGNETQERTIEVSGGIVWYNHIVGLACFDNKEGKFEIRLYDSLQKIDNSLSTNHPVNSQILLMNIFDNTLVVLSIDGSIGLFEITLNEKSHD--ISMEYIQTIPLENYIEFAACIVSFNLSSLHTEIGHN-KDVDELIRYQSLLINYSGHLLLFQRDKSFSAPRTSDKSLNSQENSFFKLAFKNTLIAKQKITFTGPLVVAYNVEIMWTPIIDEEFQSKRLKLDDWNAKIYTMENSLWLNCGSQGLRVWLPLNGGSNVTQVGEKKSKYSFLSKRIMLTFKIRNFYPLVVLNNEALLMSPMNE-FSNDFVNTPTC------LNLSFSSINKNRHIFLQHIVKELLRINLGIHALDLTFELKKLPYFNHSXXXXXXXXXXXXATSKEPIPDPLLPRVVAFIQEFPNFLRTVVQCARKTELALWSYLFESAGNPKDLFESCLMNNELDTAASYLIILQNIEHPLISQKQAILLLDAALNRSNWGLVSNLIRFLKNIVEEVFKYEHARNEFKMIEKGNYKSTKETYSSFNTK-KRYRSGGGIGMATSRQ-YSTGK--IKDIEILKSSKSAQNGNIDENCYDDLVFD 3119
++ + +Q+ ++ ++ + ++A Y ++ +GN EW D S+I I T G++L F + V ++ Y E + L + Q + + V+ I+ I +DLLVA EDG L I W G + NLT+I F D + S+A + L + R++E+ +L G V+F +G+ F+ +++L ++QI GVWA ++ + TC AVN K+R +A+G G +++ D TGAL+L H+L++ +YPD TGAV ++WSPD + + WE G SLWSV G+ L +LG + + S+ WG EGY LW I E DKS + IL FQ KS L VNP +N E +LL + R S SE + P+P Y+ NWPI+Y AID G + + GK GFA Y ++KKW+LFGN TQE+ + VSGG+ W+ + LACF+ E + E+R+Y +DN+ + V + LL++IF + +++ D SI L+ I ++ + + ++ +Q + + YI + +VS L+S+ TE G + K + +S+L+N +G L++ QRD+S P+ +K + ++ + F P+V+A +VE +W+ + KR L+ +LWL+CG G++VWLPL + + +SFLSKRIML F I N YPL VL +AL++ +NE + D +N + ++ F + + I+L HI+++LL NLG AL L LPYF H LEL+LHEVLEEEATS+EPIPDPLLP V FI EFP FL+TVV CARKTE ALW+YLF + GNPKDLFE CLM +L+TAASYLIILQN+E +S++ A LL + AL + W L ++IRFLK I +M +T+E S+ + R+RS I ++ S + + +GK ++ + S + + + D +C +++ D
Sbjct: 34 SVLSQTQLSIWYSRPSVLIASYKESAKATAQFGNYKQAEWRPDSSMIVI-TANGYILFFDIIPVGED---KYLYEPVYPKGSPHIKLNPHYKEEQCAPALNLETKKVMDLQASITSIQSMMEDLLVATEDGLLHIIHWEGMTNGRKAINLTTIPFSIDFQPSRAGSFLDFGDVHIRDMEYCATLDGFAVVFNDGRVGFITPGSNRLTADQIHGVWAPDVVDGTCVAVNNKYRLMAFGCVGGSVLVFTIDNTTGALQLSHKLELTPKQYPDMWNKTGAVKLIRWSPDCSVVMVTWECGGLSLWSVFGAHLICTLGGDFDYRADGTKKEALRICSMSWGTEGYHLWAITADSSQNTGYEMSDKSVPQQSGILQFQFIKSALTVNPCMSNQEQVLLQGEDRLYLNCGDATQTQNARNGSSQSEHKPLRDRSPFPGSSGNSQGLSTLLGHRHWHVVQIQSTYLQSNWPIRYTAIDKVGQNVAVVGKFGFAHYSLLTKKWKLFGNITQEQNMVVSGGLSWWKEFIVLACFNLSEQQEELRVYLRTSNLDNAFAHVIKVQLETLLLSIFRDMVIIFRADCSICLYSIERKKEGPNPSVCLQVLQEVSMSRYIPHPSLVVSVTLTSVRTETGISLKMPQQACDAESILLNLAGQLIMLQRDRS--GPQIREKDAKTHQHKL--------------LPFCAPVVLAQSVENVWSTC--RANKQKRHLLE-----------ALWLSCGGAGMKVWLPLFPR-------DHRKPHSFLSKRIMLPFHI-NIYPLAVLFEDALVLGAINETVAYDCLNNLSTSSEHLEVHFPFCIVERTSQIYLHHILRQLLVRNLGEQALLLAQSCAALPYFPHVLELMLHEVLEEEATSREPIPDPLLPTVAKFITEFPLFLQTVVHCARKTEYALWNYLFAAVGNPKDLFEECLMAQDLETAASYLIILQNMEAAAVSRQHATLLFNTALEQGKWDLCRHMIRFLKAI-----------GSGEMETPPATPTTQEPSSTGGFEFFRHRS---ISLSQSAENFPSGKFNLQKTHSMPSGAAGKRWSKDSDCAENMYID 1057
BLAST of RIC1 domain-containing protein vs. Ensembl Xenopus
Match: nsun3 (NOP2/Sun RNA methyltransferase family member 3 [Source:Xenbase;Acc:XB-GENE-980505]) HSP 1 Score: 534.643 bits (1376), Expect = 6.789e-164 Identity = 349/982 (35.54%), Postives = 519/982 (52.85%), Query Frame = 3
Query: 117 AIFNSSQIIVFENKNNSIVAYYCRCEESLDIYGNSINLEWNSDGSLIAIGTDKGFLLIFSVKTVSQEVNVGYQNEKEFLEEGFINRQLSLFGEIILLDVISFPYKISCICLYRDDLLVAIEDGTLSRIKWNGSLLYNQEFNLTSISFFSDLEFSKASN-LSKNEAICRNIEWLPSLSGVIVLFKNGKSAFLHIPNHKLLSEQITGVWAENLRNVTCSAVNVKFRSIAYGLKIGEAVIYKTDEETGALRLQHRLKILSNEYPDADKVTGAVTYLKWSPDNFCLALCWEYIGFSLWSVQGSLLFSSLGNKAGID--------MSLLSLDWGCEGYSLWLI----------EKPDKS--GKPAILIFQMAKSVLVVNPTKNNHEHXXXXXXXHIIFG---------PRKLLSSSETN--LEYIPYP------------------------ENYVTWNWPIKYAAIDLNGSRLVISGKHGFALYFFVSKKWRLFGNETQERTIEVSGGIVWYNHIVGLACFDNKEGKFEIRLYDSLQKIDNSLSTNHPVNSQILLMNIFDNTLVVLSIDGSIGLFEITLNEKSHD--ISMEYIQTIPLENYIEFAACIVSFNLSSLHTEIGHN-KDVDELIRYQSLLINYSGHLLLFQRDKSFSAPRTSDKSLNSQENSFFKLAFKNTLIAKQKITFTGPLVVAYNVEIMWTPIIDEEFQSKRLKLDDWNAKIYTMENSLWLNCGSQGLRVWLPLNGGSNVTQVGEKKSKYSFLSKRIMLTFKIRNFYPLVVLNNEALLMSPMNE-FSNDFVNTPTC------LNLSFSSINKNRHIFLQHIVKELLRINLGIHALDLTFELKKLPYFNHSXXXXXXXXXXXXATSKEPIPDPLLPRVVAFIQEFPNFLRTVVQCARKTELALWSYLFESAGNPKDLFESCLMNNELDTAASYLIILQNIEHPLISQKQAILLLDAALNRSNWGLVSNLIRFLKNI 2864
++ + +Q+ ++ ++ + ++A Y ++ +GN EW D S+I I F +F V + Y + L + Q + + V+ I+ I +DLLVA EDG L I W G + NLT+I F D + S+A + L + R++E+ +L G V+F +G+ F+ +++L QI GVWA ++ + TC AVN K+R +A+G G +++ D TGAL+L H+L++ +YPD TGAV ++WSPD + + WE G SLWSV G+ L +LG + + S+ WG EGY LW I E DKS + IL FQ KS L VNP +N E +LL + R S SE + P+P Y+ NWPI+Y AID G + + GK GFA Y ++KKW+LFGN TQE+ + VSGG+ W+ + LACF+ E + E+R+Y +DN+ + V + LL++IF + +++ D SI L+ I ++ + + ++ +Q + + YI + +VS L+S+ TE G + K + +S+L+N +G L++ QRD+S P+ +K + ++ + F P+V+A +VE +W+ + KR L+ +LWL+CG G++VWLPL + + +SFLSKRIML F I N YPL VL +AL++ +NE + D +N + ++ F + + I+L HI+++LL NLG AL L LPYF H LEL+LHEVLEEEATS+EPIPDPLLP V FI EFP FL+TVV CARKTE ALW+YLF + GNPKDLFE CLM +L+TAASYLIILQN+E +S++ A LL + AL + W L ++IRFLK I
Sbjct: 34 SVLSQTQLSIWYSRPSVLIASYKESAKATAQFGNYKQAEWRPDSSMIVIAVSTCFYSVFGVTYM-------YGSPHIKLNPHYKEEQCAPALNLETKKVMDLQASITSIQSMMEDLLVATEDGLLHIIHWEGMTNGRKAINLTTIPFSIDFQPSRAGSFLDFGDVHIRDMEYCATLDGFAVVFNDGRVGFITPGSNRL--TQIHGVWAPDVVDGTCVAVNNKYRLMAFGCVGGSVLVFTIDNTTGALQLSHKLELTPKQYPDMWNKTGAVKLIRWSPDCSVVMVTWECGGLSLWSVFGAHLICTLGGDFDYRADGTKKEALRICSMSWGTEGYHLWAITADSSQNTGYEMSDKSVPQQSGILQFQFIKSALTVNPCMSNQEQVLLQGEDRLYLNCGDATQTQNARNGSSQSEHKPLRDRSPFPGSSGNSQGLSTLLGHRHWHVVQIQSTYLQSNWPIRYTAIDKVGQNVAVVGKFGFAHYSLLTKKWKLFGNITQEQNMVVSGGLSWWKEFIVLACFNLSEQQEELRVYLRTSNLDNAFAHVIKVQLETLLLSIFRDMVIIFRADCSICLYSIERKKEGPNPSVCLQVLQEVSMSRYIPHPSLVVSVTLTSVRTETGISLKMPQQACDAESILLNLAGQLIMLQRDRS--GPQIREKDAKTHQHKL--------------LPFCAPVVLAQSVENVWSTC--RANKQKRHLLE-----------ALWLSCGGAGMKVWLPLFPR-------DHRKPHSFLSKRIMLPFHI-NIYPLAVLFEDALVLGAINETVAYDCLNNLSTSSEHLEVHFPFCIVERTSQIYLHHILRQLLVRNLGEQALLLAQSCAALPYFPHVLELMLHEVLEEEATSREPIPDPLLPTVAKFITEFPLFLQTVVHCARKTEYALWNYLFAAVGNPKDLFEECLMAQDLETAASYLIILQNMEAAAVSRQHATLLFNTALEQGKWDLCRHMIRFLKAI 969
BLAST of RIC1 domain-containing protein vs. Ensembl Xenopus
Match: nsun3 (NOP2/Sun RNA methyltransferase family member 3 [Source:Xenbase;Acc:XB-GENE-980505]) HSP 1 Score: 534.643 bits (1376), Expect = 1.286e-163 Identity = 362/1076 (33.64%), Postives = 559/1076 (51.95%), Query Frame = 3
Query: 117 AIFNSSQIIVFENKNNSIVAYYCRCEESLDIYGNSINLEWNSDGSLIAIGTDKGFLLIFSVKTVSQEVNVGYQNEKEF--------LEEGFINRQLSLFGEIILLDVISFPYKISCICLYRDDLLVAIEDGTLSRIKWNGSLLYNQEFNLTSISFFSDLEFSKASNLSKNEAICRNIEWLPSLSGVIVLFKNGKSAFLHIPNHKLLSEQITGVWAENLRNVTCSAVNVKFRSIAYGLKIGEAVIYKTDEETGALRLQHRLKILSNEYPDADKVTGAVTYLKWSPDNFCLALCWEYIGFSLWSVQGSLLFSSLGNKAGID--------MSLLSLDWGCEGYSLWLI----------EKPDKS--GKPAILIFQMAKSVLVVNPTKNNHEHXX-----------------------XXXXXHIIFGPRKLLSSSETNLEYIPYPENYVTWN----------WPIKYAAIDLNGSRLVISGKHGFALYFFVSKKWRLFGNETQERTIEVSGGIVWYNHIVGLACFDNKEGKFEIRLYDSLQKIDNSLSTNHPVNSQILLMNIFDNTLVVLSIDGSIGLFEITLNEKSHD--ISMEYIQTIPLENYIEFAACIVSFNLSSLHTEIGHN-KDVDELIRYQSLLINYSGHLLLFQRDKSFSAPRTSDKSLNSQENSFFKLAFKNTLIAKQKITFTGPLVVAYNVEIMWTPIIDEEFQSKRLKLDDWNAKIYTMENSLWLNCGSQGLRVWLPLNGGSNVTQVGEKKSKYSFLSKRIMLTFKIRNFYPLVVLNNEALLMSPMNE-FSNDFVNTPTC------LNLSFSSINKNRHIFLQHIVKELLRINLGIHALDLTFELKKLPYFNHSXXXXXXXXXXXXATSKEPIPDPLLPRVVAFIQEFPNFLRTVVQCARKTELALWSYLFESAGNPKDLFESCLMNNELDTAASYLIILQNIEHPLISQKQAILLLDAALNRSNWGLVSNLIRFLKNIVEEVFKYEHARNEFKMIEKGNYKSTKETYSSFNTK-KRYRSGGGIGMATSRQ-YSTGK--IKDIEILKSSKSAQNGNIDENCYDDLVFD 3119
++ + +Q+ ++ ++ + ++A Y ++ +GN EW D S+I I T G++L F + V ++ Y E + L + Q + + V+ I+ I +DLLVA EDG L I W G + NLT+I F D + S+ S L + R++E+ +L G V+F +G+ F+ +++L ++QI GVWA ++ + TC AVN K+R +A+G G +++ D TGAL+L H+L++ +YPD TGAV ++WSPD + + WE G SLWSV G+ L +LG + + S+ WG EGY LW I E DKS + IL FQ KS L VNP +N E +L S H R S N + + + W+ +P++Y AID G + + GK GFA Y ++KKW+LFGN TQE+ + VSGG+ W+ + LACF+ E + E+R+Y +DN+ + V + LL++IF + +++ D SI L+ I ++ + + ++ +Q + + YI + +VS L+S+ TE G + K + +S+L+N +G L++ QRD+S P+ +K + ++ + F P+V+A +VE +W+ + KR L+ +LWL+CG G++VWLPL + + +SFLSKRIML F I N YPL VL +AL++ +NE + D +N + ++ F + + I+L HI+++LL NLG AL L LPYF H LEL+LHEVLEEEATS+EPIPDPLLP V FI EFP FL+TVV CARKTE ALW+YLF + GNPKDLFE CLM +L+TAASYLIILQN+E +S++ A LL + AL + W L ++IRFLK I +M +T+E S+ + R+RS I ++ S + + +GK ++ + S + + + D +C +++ D
Sbjct: 34 SVLSQTQLSIWYSRPSVLIASYKESAKATAQFGNYKQAEWRPDSSMIVI-TANGYILFFDIIPVGED---KYLYEPVYPKGSPHIKLNPHYKEEQCAPALNLETKKVMDLQASITSIQSMMEDLLVATEDGLLHIIHWEGMTNGRKAINLTTIPFSIDFQPSRGSFLDFGDVHIRDMEYCATLDGFAVVFNDGRVGFITPGSNRLTADQIHGVWAPDVVDGTCVAVNNKYRLMAFGCVGGSVLVFTIDNTTGALQLSHKLELTPKQYPDMWNKTGAVKLIRWSPDCSVVMVTWECGGLSLWSVFGAHLICTLGGDFDYRADGTKKEALRICSMSWGTEGYHLWAITADSSQNTGYEMSDKSVPQQSGILQFQFIKSALTVNPCMSNQEQVLLQGEDRLYLNCGDATQTQNARNGSSQSEHKPLRDRSPFPGSSGNSQGLSTLLGHRHWHVVQHLIIFFFFPLQYTAIDKVGQNVAVVGKFGFAHYSLLTKKWKLFGNITQEQNMVVSGGLSWWKEFIVLACFNLSEQQEELRVYLRTSNLDNAFAHVIKVQLETLLLSIFRDMVIIFRADCSICLYSIERKKEGPNPSVCLQVLQEVSMSRYIPHPSLVVSVTLTSVRTETGISLKMPQQACDAESILLNLAGQLIMLQRDRS--GPQIREKDAKTHQHKL--------------LPFCAPVVLAQSVENVWSTC--RANKQKRHLLE-----------ALWLSCGGAGMKVWLPLFPR-------DHRKPHSFLSKRIMLPFHI-NIYPLAVLFEDALVLGAINETVAYDCLNNLSTSSEHLEVHFPFCIVERTSQIYLHHILRQLLVRNLGEQALLLAQSCAALPYFPHVLELMLHEVLEEEATSREPIPDPLLPTVAKFITEFPLFLQTVVHCARKTEYALWNYLFAAVGNPKDLFEECLMAQDLETAASYLIILQNMEAAAVSRQHATLLFNTALEQGKWDLCRHMIRFLKAI-----------GSGEMETPPATPTTQEPSSTGGFEFFRHRS---ISLSQSAENFPSGKFNLQKTHSMPSGAAGKRWSKDSDCAENMYID 1054
BLAST of RIC1 domain-containing protein vs. Ensembl Mouse
Match: Ric1 (RAB6A GEF complex partner 1 [Source:MGI Symbol;Acc:MGI:1924893]) HSP 1 Score: 531.946 bits (1369), Expect = 1.301e-162 Identity = 348/1027 (33.89%), Postives = 535/1027 (52.09%), Query Frame = 3
Query: 21 MYYFFNCPKRI-----SRHFVPSNITGIISSKSFALCAIFNSSQIIVFENKNNSIVAYYCRCEESLDIYGNSINLEWNSDGSLIAIGTDKGFLLIFSVKTVSQEVNVGYQNEKEFLEEGFINRQLSLFGE--------IILLDVISFPYKISCICLYRDDLLVAIEDGTLSRIKWNGSLLYNQEFNLTSISFFSDLEFSK-ASNLSKNEAICRNIEWLPSLSGVIVLFKNGKSAFLHIPNHKLLSEQITGVWAENLRNVTCSAVNVKFRSIAYGLKIGEAVIYKTDEETGALRLQHRLKILSNEYPDADKVTGAVTYLKWSPDNFCLALCWEYIGFSLWSVQGSLLFSSLGNKAGI--------DMSLLSLDWGCEGYSLWLI----------EKPDKSG--KPAILIFQMAKSVLVVNPTKNNHEHXXXXXXXHIIFGPRKLLSS-----SETNLEYIPYPE------------------------------NYVTWNWPIKYAAIDLNGSRLVISGKHGFALYFFVSKKWRLFGNETQERTIEVSGGIVWYNHIVGLACFDNKEGKFEIRLYDSLQKIDNSLSTNHPVNSQILLMNIFDNTLVVLSIDGSIGLFEITLNEKSHDI--SMEYIQTIPLENYIEFAACIVSFNLSSLHTEIGHNKDVDELIR-YQSLLINYSGHLLLFQRDKSFSAPRTSDKSLNSQENSFFKLAFKNTLIAKQKITFTGPLVVAYNVEIMWTPIIDEEFQSKRLKLDDWNAKIYTMENSLWLNCGSQGLRVWLPLNGGSNVTQVGEKKSKYSFLSKRIMLTFKIRNFYPLVVLNNEALLMSPMNE-------FSNDFVNTPTCLNLSFSSINKNRHIFLQHIVKELLRINLGIHALDLTFELKKLPYFNHSXXXXXXXXXXXXATSKEPIPDPLLPRVVAFIQEFPNFLRTVVQCARKTELALWSYLFESAGNPKDLFESCLMNNELDTAASYLIILQNIEHPLISQKQAILLLDAALNRSNWGLVSNLIRFLKNI 2864
MY+ PKR+ S P ++ S A A+ +++ ++ ++ + ++ Y +S +G+ EW D ++IA+ T G++L F + + + Y E + + + + F E + + ++ I + +DLLVA DG L I W G + NL+++ F DL+ S+ S L + +++E+ +L G V+F +GK F+ + + +EQ+ GVW +++ + TC AVN K+R +A+G G +Y D TGA+ L H+L++ + +YPD TGAV ++WSPDN + + WEY G SLWSV G+ L +LG + + S+ WG EGY LW+I E +S +P+IL+FQ KSVL VNP +N E +LL + + + S E +P E Y+ NWPI+++AID G + ++GK GFA Y ++KKW+LFGN TQE+ + V+GG+ W++ + LAC++ + + E+R+Y +DN+ + + LL+++F + +VV D SI L+ I + S++ +Q + + YI +VS L+S+ TE G + + + R +S+++N +G L++ QRD+S R D N ++ + F P+V+A +VE +WT + KR L+ +LWL+CG G++VWLPL + + +SFLS+RIML F I N YPL VL +AL++ +N+ ++ + F + + I+L HI+++LL NLG AL L LPYF H LEL+LHEVLEEEATS+EPIPDPLLP V FI EFP FL+TVV CARKTE ALW+YLF + GNPKDLFE CLM +LDTAASYLIILQN+E P +S++ A LL + AL + W L ++IRFLK I
Sbjct: 1 MYFLSGWPKRLLCAPRSPAEAPLHVQ---SDPRRAFFAVLAPARLSIWYSRPSVLIVTYKEPAKSSTQFGSYKQAEWRPDSTMIAVSTANGYILFFHITSSRGD---KYLYEPVYPKGSPQMKGIPHFKEEHCAPALNLEMKKILDLQAPIMSLQSVLEDLLVATSDGLLHLIHWEGMTNGRKAINLSTVPFSVDLQSSRVGSFLGFADVHIKDMEYCATLDGFAVVFNDGKVGFITPVSSRFTAEQLHGVWPQDVIDGTCVAVNNKYRLMAFGCASGCVQVYTIDNTTGAMLLSHKLELTAKQYPDIWNKTGAVKLIRWSPDNSAVIVTWEYGGLSLWSVFGAQLICTLGGDFAYRSDGTKKDPLKINSMSWGAEGYHLWVISGLGSQHTQIETDLRSTVKEPSILLFQFIKSVLTVNPCMSNQEQVLLQGEDRLYLNCGEASQAQNPKYSSARAERMPRHEKSPFADGGLEAPGLSTLLGHRHWHVVQISSTYLESNWPIRFSAIDKLGQNIAVAGKFGFAHYSLLTKKWKLFGNITQEQNMIVTGGLAWWDDFMVLACYNLSDRQEELRIYLRTSNLDNAFAHVTKAPMETLLLSVFRDMVVVFRADCSICLYSIERKSDGSNTTASVQVLQEVSMSRYIPHPFLVVSVTLTSVSTENGISLKMPQQARDAESIMLNLAGQLIMMQRDRSGPQIREKDSHPNQ----------------RKLLPFCPPVVLAQSVENVWTTC--RANKQKRHLLE-----------ALWLSCGGAGMKVWLPLFPR-------DHRKPHSFLSQRIMLPFHI-NIYPLAVLFEDALVLGAVNDTLLYDSLYTRSSAREQLEVLFPFCVVERTSQIYLHHILRQLLVRNLGEQALLLAQSCAALPYFPHVLELMLHEVLEEEATSREPIPDPLLPTVAKFITEFPLFLQTVVHCARKTEYALWNYLFAAVGNPKDLFEECLMAQDLDTAASYLIILQNMEVPAVSRQHATLLFNTALEQGKWDLCRHMIRFLKAI 984
BLAST of RIC1 domain-containing protein vs. Ensembl Mouse
Match: Ric1 (RAB6A GEF complex partner 1 [Source:MGI Symbol;Acc:MGI:1924893]) HSP 1 Score: 475.707 bits (1223), Expect = 4.591e-143 Identity = 315/925 (34.05%), Postives = 484/925 (52.32%), Query Frame = 3
Query: 231 EWNSDGSLIAIGTDKGFLLIFSVKTVSQEVNVGYQNEKEFLEEGFINRQLSLFGE--------IILLDVISFPYKISCICLYRDDLLVAIEDGTLSRIKWNGSLLYNQEFNLTSISFFSDLEFSK-ASNLSKNEAICRNIEWLPSLSGVIVLFKNGKSAFLHIPNHKLLSEQITGVWAENLRNVTCSAVNVKFRSIAYGLKIGEAVIYKTDEETGALRLQHRLKILSNEYPDADKVTGAVTYLKWSPDNFCLALCWEYIGFSLWSVQGSLLFSSLGNKAGI--------DMSLLSLDWGCEGYSLWLI----------EKPDKSG--KPAILIFQMAKSVLVVNPTKNNHEHXXXXXXXHIIFGPRKLLSS-----SETNLEYIPYPENYVTWNWPIKYAAIDLNGSRLVISGKHGFALYF---FVSKKWRLFGNETQERTIEVSGGIVWYNHIVGLACFDNKEGKFEIRLYDSLQKIDNSLSTNHPVNSQILLMNIFDNTLVVLSIDGSIGLFEITLNEKSHDI--SMEYIQTIPLENYIEFAACIVSFNLSSLHTEIGHNKDVDELIR-YQSLLINYSGHLLLFQRDKSFSAPRTSDKSLNSQENSFFKLAFKNTLIAKQKITFTGPLVVAYNVEIMWTPIIDEEFQSKRLKLDDWNAKIYTMENSLWLNCGSQGLRVWLPLNGGSNVTQVGEKKSKYSFLSKRIMLTFKIRNFYPLVVLNNEALLMSPMNE-------FSNDFVNTPTCLNLSFSSINKNRHIFLQHIVKELLRINLGIHALDLTFELKKLPYFNHSXXXXXXXXXXXXATSKEPIPDPLLPRVVAFIQEFPNFLRTVVQCARKTELALWSYLFESAGNPKDLFESCLMNNELDTAASYLIILQNIEHPLISQKQAILLLDAALNRSNWGLVSNLIRFLKNI 2864
EW D ++IA+ T G++L F + + + Y E + + + + F E + + ++ I + +DLLVA DG L I W G + NL+++ F DL+ S+ S L + +++E+ +L G V+F +GK F+ + + +EQ+ GVW +++ + TC AVN K+R +A+G G +Y D TGA+ L H+L++ + +YPD TGAV ++WSPDN + + WEY G SLWSV G+ L +LG + + S+ WG EGY LW+I E +S +P+IL+FQ KSVL VNP +N E +LL + + + S E +P E P ++ G ++ +H + ++ W + +E+ + V+GG+ W++ + LAC++ + + E+R+Y +DN+ + + LL+++F + +VV D SI L+ I + S++ +Q + + YI +VS L+S+ TE G + + + R +S+++N +G L++ QRD+S R D N ++ + F P+V+A +VE +WT + KR L+ +LWL+CG G++VWLPL + + +SFLS+RIML F I N YPL VL +AL++ +N+ ++ + F + + I+L HI+++LL NLG AL L LPYF H LEL+LHEVLEEEATS+EPIPDPLLP V FI EFP FL+TVV CARKTE ALW+YLF + GNPKDLFE CLM +LDTAASYLIILQN+E P +S++ A LL + AL + W L ++IRFLK I
Sbjct: 2 EWRPDSTMIAVSTANGYILFFHITSSRGD---KYLYEPVYPKGSPQMKGIPHFKEEHCAPALNLEMKKILDLQAPIMSLQSVLEDLLVATSDGLLHLIHWEGMTNGRKAINLSTVPFSVDLQSSRVGSFLGFADVHIKDMEYCATLDGFAVVFNDGKVGFITPVSSRFTAEQLHGVWPQDVIDGTCVAVNNKYRLMAFGCASGCVQVYTIDNTTGAMLLSHKLELTAKQYPDIWNKTGAVKLIRWSPDNSAVIVTWEYGGLSLWSVFGAQLICTLGGDFAYRSDGTKKDPLKINSMSWGAEGYHLWVISGLGSQHTQIETDLRSTVKEPSILLFQFIKSVLTVNPCMSNQEQVLLQGEDRLYLNCGEASQAQNPKYSSARAERMPRHEKS-----PFADGGLEAPGLSTLLGHRHWHVVQISSTYLESNWPI-----REQNMIVTGGLAWWDDFMVLACYNLSDRQEELRIYLRTSNLDNAFAHVTKAPMETLLLSVFRDMVVVFRADCSICLYSIERKSDGSNTTASVQVLQEVSMSRYIPHPFLVVSVTLTSVSTENGISLKMPQQARDAESIMLNLAGQLIMMQRDRSGPQIREKDSHPNQ----------------RKLLPFCPPVVLAQSVENVWTTC--RANKQKRHLLE-----------ALWLSCGGAGMKVWLPLFPR-------DHRKPHSFLSQRIMLPFHI-NIYPLAVLFEDALVLGAVNDTLLYDSLYTRSSAREQLEVLFPFCVVERTSQIYLHHILRQLLVRNLGEQALLLAQSCAALPYFPHVLELMLHEVLEEEATSREPIPDPLLPTVAKFITEFPLFLQTVVHCARKTEYALWNYLFAAVGNPKDLFEECLMAQDLDTAASYLIILQNMEVPAVSRQHATLLFNTALEQGKWDLCRHMIRFLKAI 876
BLAST of RIC1 domain-containing protein vs. Ensembl Mouse
Match: Ric1 (RAB6A GEF complex partner 1 [Source:MGI Symbol;Acc:MGI:1924893]) HSP 1 Score: 154.836 bits (390), Expect = 1.073e-42 Identity = 87/131 (66.41%), Postives = 99/131 (75.57%), Query Frame = 3
Query: 2358 FSSINKNRHIFLQHIVKELLRINLGIHALDLTFELKKLPYFNHSXXXXXXXXXXXXATSKEPIPDPLLPRVVAFIQEFPNFLRTVVQCARKTELALWSYLFESAGNPKDLFESCLMNNELDTAASYLIILQ 2750
F + + I+L HI+++LL NLG AL L LPYF H LEL+LHEVLEEEATS+EPIPDPLLP V FI EFP FL+TVV CARKTE ALW+YLF + GNPKDLFE CLM +LDTAASYLIILQ
Sbjct: 28 FCVVERTSQIYLHHILRQLLVRNLGEQALLLAQSCAALPYFPHVLELMLHEVLEEEATSREPIPDPLLPTVAKFITEFPLFLQTVVHCARKTEYALWNYLFAAVGNPKDLFEECLMAQDLDTAASYLIILQ 158
BLAST of RIC1 domain-containing protein vs. UniProt/SwissProt
Match: sp|Q4ADV7|RIC1_HUMAN (RAB6A-GEF complex partner protein 1 OS=Homo sapiens OX=9606 GN=RIC1 PE=1 SV=2) HSP 1 Score: 543.502 bits (1399), Expect = 4.793e-166 Identity = 354/1033 (34.27%), Postives = 541/1033 (52.37%), Query Frame = 3
Query: 21 MYYFFNCPKRI-----SRHFVPSNITGIISSKSFALCAIFNSSQIIVFENKNNSIVAYYCRCEESLDIYGNSINLEWNSDGSLIAIGTDKGFLLIFSVKT----------VSQEVNVGYQNEKEFLEEGFINRQLSLFGEIILLDVISFPYKISCICLYRDDLLVAIEDGTLSRIKWNGSLLYNQEFNLTSISFFSDLEFSK-ASNLSKNEAICRNIEWLPSLSGVIVLFKNGKSAFLHIPNHKLLSEQITGVWAENLRNVTCSAVNVKFRSIAYGLKIGEAVIYKTDEETGALRLQHRLKILSNEYPDADKVTGAVTYLKWSPDNFCLALCWEYIGFSLWSVQGSLLFSSLGNKAGI--------DMSLLSLDWGCEGYSLWLI----------EKPDKS--GKPAILIFQMAKSVLVVNPTKNNHEHXXXXXXXHIIFG---------PRKLLSSSETNLEYIPYPE------------------------------NYVTWNWPIKYAAIDLNGSRLVISGKHGFALYFFVSKKWRLFGNETQERTIEVSGGIVWYNHIVGLACFDNKEGKFEIRLYDSLQKIDNSLSTNHPVNSQILLMNIFDNTLVVLSIDGSIGLFEITLNEKSHDIS--MEYIQTIPLENYIEFAACIVSFNLSSLHTEIGHNKDVDELIR-YQSLLINYSGHLLLFQRDKSFSAPRTSDKSLNSQENSFFKLAFKNTLIAKQKITFTGPLVVAYNVEIMWTPIIDEEFQSKRLKLDDWNAKIYTMENSLWLNCGSQGLRVWLPLNGGSNVTQVGEKKSKYSFLSKRIMLTFKIRNFYPLVVLNNEALLMSPMNE-------FSNDFVNTPTCLNLSFSSINKNRHIFLQHIVKELLRINLGIHALDLTFELKKLPYFNHSXXXXXXXXXXXXATSKEPIPDPLLPRVVAFIQEFPNFLRTVVQCARKTELALWSYLFESAGNPKDLFESCLMNNELDTAASYLIILQNIEHPLISQKQAILLLDAALNRSNWGLVSNLIRFLKNI 2864
MY+ PKR+ S P ++ S A A+ ++++ ++ ++ + ++ Y +S +G+ EW D ++IA+ T G++L F + + V + + + F EE Q + + + ++ I + +DLLVA DG L I W G + NL ++ F DL+ S+ S L + R++E+ +L G V+F +GK F+ + + +EQ+ GVW +++ + TC AVN K+R +A+G G +Y D TGA+ L H+L++ + +YPD TGAV ++WSPDN + + WEY G SLWSV G+ L +LG + + S+ WG EGY LW+I E +S +P+IL+FQ KSVL VNP +N E +LL + PR SS T+ E+ P E Y+ NWPI+++AID G + + GK GFA Y ++KKW+LFGN TQE+ + V+GG+ W+N + LAC++ + + E+R+Y +DN+ + ++ LL+++F + ++V D SI L+ I + + ++ +Q + + YI +VS L+S+ TE G + + R +S+++N +G L++ QRD+S R D + N+Q ++ + F P+V+A +VE +WT + KR L+ +LWL+CG G++VWLPL + + +SFLS+RIML F I N YPL VL +AL++ +N+ ++ + + F + + I+L HI+++LL NLG AL L LPYF H LEL+LHEVLEEEATS+EPIPDPLLP V FI EFP FL+TVV CARKTE ALW+YLF + GNPKDLFE CLM +LDTAASYLIILQN+E P +S++ A LL + AL + W L ++IRFLK I
Sbjct: 1 MYFLSGWPKRLLCPLGSPAEAPFHVQ---SDPQRAFFAVLAAARLSIWYSRPSVLIVTYKEPAKSSTQFGSYKQAEWRPDSTMIAVSTANGYILFFHITSTRGDKYLYEPVYPKGSPQMKGTPHFKEE-----QCAPALNLEMRKILDLQAPIMSLQSVLEDLLVATSDGLLHLIHWEGMTNGRKAINLCTVPFSVDLQSSRVGSFLGFTDVHIRDMEYCATLDGFAVVFNDGKVGFITPVSSRFTAEQLHGVWPQDVVDGTCVAVNNKYRLMAFGCVSGSVQVYTIDNSTGAMLLSHKLELTAKQYPDIWNKTGAVKLMRWSPDNSVVIVTWEYGGLSLWSVFGAQLICTLGGDFAYRSDGTKKDPLKINSMSWGAEGYHLWVISGFGSQNTEIESDLRSVVKQPSILLFQFIKSVLTVNPCMSNQEQVLLQGEDRLYLNCGEASQTQNPR----SSSTHSEHKPSREKSPFADGGLESQGLSTLLGHRHWHVVQISSTYLESNWPIRFSAIDKLGQNIAVVGKFGFAHYSLLTKKWKLFGNITQEQNMIVTGGLAWWNDFMVLACYNINDRQEELRVYLRTSNLDNAFAHVTKAQAETLLLSVFQDMVIVFRADCSICLYSIERKSDGPNTTAGIQVLQEVSMSRYIPHPFLVVSVTLTSVSTENGITLKMPQQARGAESIMLNLAGQLIMMQRDRSGPQIREKDSNPNNQ---------------RKLLPFCPPVVLAQSVENVWTTC--RANKQKRHLLE-----------ALWLSCGGAGMKVWLPLFPR-------DHRKPHSFLSQRIMLPFHI-NIYPLAVLFEDALVLGAVNDTLLYDSLYTRNNAREQLEVLFPFCVVERTSQIYLHHILRQLLVRNLGEQALLLAQSCATLPYFPHVLELMLHEVLEEEATSREPIPDPLLPTVAKFITEFPLFLQTVVHCARKTEYALWNYLFAAVGNPKDLFEECLMAQDLDTAASYLIILQNMEVPAVSRQHATLLFNTALEQGKWDLCRHMIRFLKAI 985
BLAST of RIC1 domain-containing protein vs. UniProt/SwissProt
Match: sp|Q69ZJ7|RIC1_MOUSE (RAB6A-GEF complex partner protein 1 OS=Mus musculus OX=10090 GN=Ric1 PE=1 SV=2) HSP 1 Score: 531.946 bits (1369), Expect = 7.975e-162 Identity = 348/1027 (33.89%), Postives = 535/1027 (52.09%), Query Frame = 3
Query: 21 MYYFFNCPKRI-----SRHFVPSNITGIISSKSFALCAIFNSSQIIVFENKNNSIVAYYCRCEESLDIYGNSINLEWNSDGSLIAIGTDKGFLLIFSVKTVSQEVNVGYQNEKEFLEEGFINRQLSLFGE--------IILLDVISFPYKISCICLYRDDLLVAIEDGTLSRIKWNGSLLYNQEFNLTSISFFSDLEFSK-ASNLSKNEAICRNIEWLPSLSGVIVLFKNGKSAFLHIPNHKLLSEQITGVWAENLRNVTCSAVNVKFRSIAYGLKIGEAVIYKTDEETGALRLQHRLKILSNEYPDADKVTGAVTYLKWSPDNFCLALCWEYIGFSLWSVQGSLLFSSLGNKAGI--------DMSLLSLDWGCEGYSLWLI----------EKPDKSG--KPAILIFQMAKSVLVVNPTKNNHEHXXXXXXXHIIFGPRKLLSS-----SETNLEYIPYPE------------------------------NYVTWNWPIKYAAIDLNGSRLVISGKHGFALYFFVSKKWRLFGNETQERTIEVSGGIVWYNHIVGLACFDNKEGKFEIRLYDSLQKIDNSLSTNHPVNSQILLMNIFDNTLVVLSIDGSIGLFEITLNEKSHDI--SMEYIQTIPLENYIEFAACIVSFNLSSLHTEIGHNKDVDELIR-YQSLLINYSGHLLLFQRDKSFSAPRTSDKSLNSQENSFFKLAFKNTLIAKQKITFTGPLVVAYNVEIMWTPIIDEEFQSKRLKLDDWNAKIYTMENSLWLNCGSQGLRVWLPLNGGSNVTQVGEKKSKYSFLSKRIMLTFKIRNFYPLVVLNNEALLMSPMNE-------FSNDFVNTPTCLNLSFSSINKNRHIFLQHIVKELLRINLGIHALDLTFELKKLPYFNHSXXXXXXXXXXXXATSKEPIPDPLLPRVVAFIQEFPNFLRTVVQCARKTELALWSYLFESAGNPKDLFESCLMNNELDTAASYLIILQNIEHPLISQKQAILLLDAALNRSNWGLVSNLIRFLKNI 2864
MY+ PKR+ S P ++ S A A+ +++ ++ ++ + ++ Y +S +G+ EW D ++IA+ T G++L F + + + Y E + + + + F E + + ++ I + +DLLVA DG L I W G + NL+++ F DL+ S+ S L + +++E+ +L G V+F +GK F+ + + +EQ+ GVW +++ + TC AVN K+R +A+G G +Y D TGA+ L H+L++ + +YPD TGAV ++WSPDN + + WEY G SLWSV G+ L +LG + + S+ WG EGY LW+I E +S +P+IL+FQ KSVL VNP +N E +LL + + + S E +P E Y+ NWPI+++AID G + ++GK GFA Y ++KKW+LFGN TQE+ + V+GG+ W++ + LAC++ + + E+R+Y +DN+ + + LL+++F + +VV D SI L+ I + S++ +Q + + YI +VS L+S+ TE G + + + R +S+++N +G L++ QRD+S R D N ++ + F P+V+A +VE +WT + KR L+ +LWL+CG G++VWLPL + + +SFLS+RIML F I N YPL VL +AL++ +N+ ++ + F + + I+L HI+++LL NLG AL L LPYF H LEL+LHEVLEEEATS+EPIPDPLLP V FI EFP FL+TVV CARKTE ALW+YLF + GNPKDLFE CLM +LDTAASYLIILQN+E P +S++ A LL + AL + W L ++IRFLK I
Sbjct: 1 MYFLSGWPKRLLCAPRSPAEAPLHVQ---SDPRRAFFAVLAPARLSIWYSRPSVLIVTYKEPAKSSTQFGSYKQAEWRPDSTMIAVSTANGYILFFHITSSRGD---KYLYEPVYPKGSPQMKGIPHFKEEHCAPALNLEMKKILDLQAPIMSLQSVLEDLLVATSDGLLHLIHWEGMTNGRKAINLSTVPFSVDLQSSRVGSFLGFADVHIKDMEYCATLDGFAVVFNDGKVGFITPVSSRFTAEQLHGVWPQDVIDGTCVAVNNKYRLMAFGCASGCVQVYTIDNTTGAMLLSHKLELTAKQYPDIWNKTGAVKLIRWSPDNSAVIVTWEYGGLSLWSVFGAQLICTLGGDFAYRSDGTKKDPLKINSMSWGAEGYHLWVISGLGSQHTQIETDLRSTVKEPSILLFQFIKSVLTVNPCMSNQEQVLLQGEDRLYLNCGEASQAQNPKYSSARAERMPRHEKSPFADGGLEAPGLSTLLGHRHWHVVQISSTYLESNWPIRFSAIDKLGQNIAVAGKFGFAHYSLLTKKWKLFGNITQEQNMIVTGGLAWWDDFMVLACYNLSDCQEELRIYLRTSNLDNAFAHVTKAPMETLLLSVFRDMVVVFRADCSICLYSIERKSDGSNTTASVQVLQEVSMSRYIPHPFLVVSVTLTSVSTENGISLKMPQQARDAESIMLNLAGQLIMMQRDRSGPQIREKDSHPNQ----------------RKLLPFCPPVVLAQSVENVWTTC--RANKQKRHLLE-----------ALWLSCGGAGMKVWLPLFPR-------DHRKPHSFLSQRIMLPFHI-NIYPLAVLFEDALVLGAVNDTLLYDSLYTRSSAREQLEVLFPFCVVERTSQIYLHHILRQLLVRNLGEQALLLAQSCAALPYFPHVLELMLHEVLEEEATSREPIPDPLLPTVAKFITEFPLFLQTVVHCARKTEYALWNYLFAAVGNPKDLFEECLMAQDLDTAASYLIILQNMEVPAVSRQHATLLFNTALEQGKWDLCRHMIRFLKAI 984
BLAST of RIC1 domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9V3C5|RIC1_DROME (Guanine nucleotide exchange factor subunit Rich OS=Drosophila melanogaster OX=7227 GN=Rich PE=1 SV=1) HSP 1 Score: 465.307 bits (1196), Expect = 1.334e-137 Identity = 326/1031 (31.62%), Postives = 516/1031 (50.05%), Query Frame = 3
Query: 21 MYYFFNCPKRIS----------RHFVPSNITGIISSKSFALCAIFNSSQIIVFENKNNSIVAYYCRCEESLDIYGNSINLEWNSDGSLIAIGTDKGFLLIFSVK------TVSQEVNVGYQNEKEFLEEGFINRQLSLFGEIILLDVISFPYKISCICLYRDDLLVAIEDGTLSRIKWNGSLLYNQEFNLTSISF--FSDLEF-------SKASNLSK--NEAICRNIEWLPSLSGVIVLFKNGKSAFLHIPNH-KLLSEQITGVWAENLRNVTCSAVNVKFRSIAYGLKIGEAVIYKTDEETGALRLQHRLKILSNEYPDADKVTGAVTYLKWSPDNFCLALCWEYIGFSLWSVQGSLLFSSLGNKAGIDMSLLS--------LDWGCEGYSLWLIEKPDKSGKPAILIFQMAKSVLVVNPTKNNHEH-----------------XXXXXXXHIIFGPRKLLSSSET--------NLEYIPY----------------PENYVTWNWPIKYAAIDLNGSRLVISGKHGFALYFFVSKKWRLFGNETQERTIEVSGGIVWYNHIVGLACFDNKEGKFEIRLYDSLQKIDNSLSTNHPVNSQILLMNIFDNTLVVLSIDGSIGLFEITLNEKSHDISMEYIQTIPLENYIEFAACIVSFNLSSLHTEIGHNKDVDELIRYQSLLINYSGHLLLFQRDKSFSAPRTSDKSLNSQENSFFKLAFKNTLIAKQKITFTGPLVVAYNVEIMWTPIIDEEFQSKRLKLDDWNAKIYTMENSLWLNCGSQGLRVWLPLNGGSNVTQVGEKKSK---YSFLSKRIMLTFKIRNFYPLVVLNNEALLMSPMNE---FSNDFVNTPTCLNLSFSSINKNRHIFLQHIVKELLRINLGIHALDLTFELKKLPYFNHSXXXXXXXXXXXXATSKEPIPDPLLPRVVAFIQEFPNFLRTVVQCARKTELALWSYLFESAGNPKDLFESCLMNNELDTAASYLIILQNIEHPLISQKQAILLLDAALNRSNWGLVSNLIRFLKNI 2864
MYY PKR+ RH + ++++ I+ ++ +I +AY+ R E+SL YG + + W D +A+ T G LL++ + + Q+++ + K E FI + L V + C+ +LL+A + L R++W + L ++S D+ F A N+ ++ ++E+ P + G +F + ++AFL I NH + ++ + G W ++ + + +VN KFR +AYG + +Y D+ TG L HRL + N PD+ G+V LKWSPD LA+ W G SLWS G+LL S+L G+++ L+ L+W EGY L++++ + K +L Q KS L +NP H L + SH F P L S E L+ P+ P NY NWPI+YAAID +G L ++G+ G A Y V+++W+LFGNE+QE+ VSGG++W++ V + C+ + E+R Y + K+DN V + ++ +N F + L+VL+ DG + LF ++ N ++ + +E + +++ ACIVS +++L E+ + + +++++N G +L+ QRD P NTL+A +A VE+ W + + M + LWL G+ G+RVWLP+ + GE+ +SF+SKRIML+F ++ YPLVVL + +++ NE ++N+ V+ +L F+ + + I+L ++++L++ NLG A ++ LPYF H+LELLLHEVLEEEATSK+PIPD LP ++ FI+EFP +L T+VQCARKTE+ALW YLF AG PKDLF+ CL + +LDTAASYLIILQN+E ++S++ A +LLD AL + W L +LIRFLK I
Sbjct: 1 MYYPVGWPKRVGLALPGESASIRHICCDAVKILVAAVGDDFLGIWYANPLIP--------IAYFRRTEDSLRQYGANQLIVWKPDSRQLALLTASGSLLLYQLDFEANGMGILQQIDPPAASLKRDSAELFIKENIPRLSLRELCSVTLGSVITTVCCISLSELLLATQSCELLRLQWTELEHAENDLELPALSSIKLRDIPFYVQQQPQQSARNVPPLNRDSYVASLEYSPFIGGCAAVFSDRRAAFL-IANHLRFETDHMHGFWVPDVEDASVCSVNHKFRLLAYGQESSAVKVYAIDDATGGLEFSHRLILTENILPDS---LGSVNELKWSPDGCVLAVSWTNGGLSLWSTFGALLMSTLSWDFGLNVDLVCQNPLKIRRLEWSTEGYQLFMLKLHPEKDKSNVLQLQFVKSALSMNPCMTTSPHILLQGDDCLYLNQGNNLELTYAGSHGTF-PSSGLGSDEDISGDGDCLELKQSPHTGSILTESKYWTVLQLPLNYAATNWPIRYAAIDPDGLHLAVAGRTGLAHYSLVTRRWKLFGNESQEKDFVVSGGLLWWHGFVVMGCYSLLDRTDELRCYPADCKLDNQYGHKLQVRAPVISLNSFRHQLIVLTADGIVSLFNMSKN-SAYALDIECAYELDVKSICIHPACIVSLTVTNLKNELKPQGQLGG-DQAETIIVNVCGRILMIQRDAGEQVP--------------------NTLLAT---------CLASCVEVFWL---------------SHSLERCAMRDCLWLYSGAHGMRVWLPILPPGRERREGEQGGAQRLHSFMSKRIMLSFPLK-LYPLVVLFDNVIVLGVENESTLYANEQVSH---FSLPFAVMERKSQIYLHKVLRQLIKRNLGYSAWEMAQSCCSLPYFPHALELLLHEVLEEEATSKQPIPDAQLPSILDFIREFPVYLETIVQCARKTEIALWPYLFSMAGKPKDLFQMCLQSEQLDTAASYLIILQNLEPSVVSKQYATMLLDIALQQRKWELAKDLIRFLKAI 968
BLAST of RIC1 domain-containing protein vs. UniProt/SwissProt
Match: sp|Q09417|RIC1_CAEEL (Guanine nucleotide exchange factor subunit R06F6.8 OS=Caenorhabditis elegans OX=6239 GN=R06F6.8 PE=3 SV=2) HSP 1 Score: 375.17 bits (962), Expect = 4.725e-106 Identity = 267/996 (26.81%), Postives = 466/996 (46.79%), Query Frame = 3
Query: 234 WNSDGSLIAIGTDKGFLLIFSVKTVSQEVNVGY---------QNEKEFLEEGFINRQLSLFGEIILLDVISFPYKISCICLYRDDLLVAIEDGTLSRIKWNGSLLYNQEFNLTSISFFSDLEFSKASNLSKNEAICRNIEWLPSLSGVIVLFKNGKSAFLHIPNHKLLSEQITGVWAENLRNVTCSAVNVKFRSIAYGLKIGEAVIYKTDEETGALRLQHRLKILSNEYPDADKVTGAVTYLKWSPDNFCLALCWEYIGFSLWSVQGSLLFSSLGNKAGIDMSLL----------SLDWGCEGYSLWLIEKPDKSGKPAILIFQ-MAKSVLVVNPTKNNHEHXXXXXXXHIIFGPRK----LLSSSETNLEYIPYPENYVTWNWPIKYAAIDLNGSRLVISGKHGFALYFFVSKKWRLFGNETQERTIEVSGGI-VWYNHIVGLACFDNKEGKFEIRLYDSLQKIDNSLSTNHPVNSQILLMNIFDNTLVVLSIDGSIGLFEITLN-EKSHD----ISMEYIQTIPLENYIEFAACIVSFNLSSLHTEIGHNKDVDELIRYQSLLINYSGHLLLFQRDKSFSAPRTSDKSLNSQENSFFKLAFKNTLIAKQKITFTGPLVVAYNVEIMW---------TPIIDEEFQSKRLKLDDWNAKIYT--------------------MENSLWLNCGSQGLRVWLPLNGGSNVTQVGEKKSKYSFLSKRIMLTFKIRNFYPLVVLNNEALLM---SPMNEFSNDFVNTPTCLNLSFSSINKNRHIFLQHIVKELLRINLGIHALDLTFELKKLPYFNHSXXXXXXXXXXXXATSKEPIPDPLLPRVVAFIQEFPNFLRTVVQCARKTELALWSYLFESAGNPKDLFESCLMNNELDTAASYLIILQNIEHPLISQKQAILLLDAALNRSNWGLVSNLIRFLKNI----VEEVFKYEHARNEFKMIEKGNYKSTKETYSSFNTKKRYRSGGGIGMATSRQYS 3023
W D + IA+ T++ +LI+++ E + +N E +G +R + I++++ P +C RD+ LV +++G + W G ++ + F +SI F D SK+ N++ + + P L G ++ +G+ A L + I GVWA N+++ TC VN KF I +G K G+ Y DE G+L R+ PD G V + + + W + + + +F+S G ++ ++ + +++WG EG+ LWL G L+ Q +S +P + + +L+S S ++ + + + ++I Y++ NWP++YA+ D N LV++G G A +++W++FGNETQE+ + V+GG+ +W + ++G+ K + Y Q++D+ ++ + + ++ + D+ V I I L+++T + E D +S E + I + + CIVS ++ L+ ++ ++L+N SG L+ TL + P+V+A VE MW T +++ K + + N I + + N+LW+ CG++G++VW+PL G E +F++KRIML F++ + YP+V+ + L M S + + N +++ +++N +F+ H++++LL+ NLG+ AL+L + LP+F H+LELLLH VLEEEATS EPIPDPLLPR VAFI EFP FL+TV CARKTELALW LF+ G+P LFE CL +L+ AAS++I+LQN+E +S QA L+ AL W + ++RF ++I ++ F+ + + + S S+ R+++G G ++S
Sbjct: 78 WKPDSTSIAVTTNQCKILIYNLDLRDDEQCYNFTDSADPYFQRNSPELFIKG--SRPTAHLHPTIIINLADIP---TCCVPSRDEFLVCLQNGFTHHVTWTGEIIASLSFRASSIPFSVDQLQSKSENITSKSTYIFDAVYAPLLGGFAIVLSDGQGALLTSNDPNFAPNAILGVWAPNMKDATCCDVNHKFLLILFGCKNGDVCAYNIDELNGSLVQSFRVAPKVTNGPDLTNRLGPVHRITALANGYGFGAIWSPLSGAHALPRLVAVFTSFGAQSFCNLEGVVEEDQNDRYTAIEWGPEGFQLWL-------GTENELMMQPFVRSASCSSPAMEHCDRAVLMSDSQVLISAARDREAEACAPHSVWDHITVTHEYLSSNWPLRYASTDRNYKHLVVAGDQGMAYCSLSNRRWKIFGNETQEKNLLVTGGVFIWNDDVIGVVGVAADTDKSHLSFYPISQRLDSRYASVVDLEHKSVMSVLRDDVCAVFDISAQITLYKLTAHLETGRDAFTKVSTEIVTVIRINEIVPHPTCIVSLQMTQLNLDVRGKLSPAFYSSIDTVLVNISGRLI--------------------------------TLSVNEDGKLHQPMVIASYVEKMWHDRCQVSQSTQSQNQDLPWKNHRRNGSNVSIQSVSTSTTSEPSSPMNQSCSSHLSNALWIACGAKGIKVWMPLVPGKRNLATQE----MTFIAKRIMLPFEL-DIYPIVISAKDCLAMGVESQLQHVARASRNQGQMESITMYGLHRNSEVFVHHLLRQLLKRNLGVFALELAGACRSLPHFTHALELLLHGVLEEEATSSEPIPDPLLPRCVAFIHEFPEFLKTVAHCARKTELALWRTLFDVTGSPNALFEECLQLKQLENAASFVIVLQNLETTEVSMDQAARLVKEALEEKKWTIAKEMVRFARSIGSEDIDAFFRTPPPSAKTSLSRRPTVSSPSADSSTEFVINRFQAGAAGGRLNKVRHS 1024
BLAST of RIC1 domain-containing protein vs. UniProt/SwissProt
Match: sp|O42656|RIC1_SCHPO (Guanine nucleotide exchange factor subunit ric1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=ric1 PE=1 SV=2) HSP 1 Score: 114.39 bits (285), Expect = 4.042e-24 Identity = 147/596 (24.66%), Postives = 254/596 (42.62%), Query Frame = 3
Query: 1278 IPYPENYVTWNWPIKYAAIDLNGSRLVISGKHGFALYFFVSKKWRLFGNETQERTIEVSGGIVWYNH--IVGLACFDNKEGKFEIRLYDSLQKIDNSLS-TNHPVNSQILLMNIFDN-TLVVLSIDGSIGLFEITLNEKSHDISMEYIQTIPLENYIEFAACIVSFNLSSLHTEIGHNKDVDELIRYQSLLINYSGHLLLFQRDKSFSAPRTSDKSLNSQENSFFKL--------AFKNTLIAKQK-----ITFTGPLVVAYNVEIMWTPIID--------------EEFQSKRLKLDDWNAKIYTMENSLWLNCGSQGLRVWLPLNGGSNVTQVGEKKSKYSFLSKRIMLTFKIRNFYPLVVLNNEALLMSPMNEFSNDFVNTPTCLNLSFSSINKNRHIFLQHIVKELLRINLGIHALDLTFELKKLPYFNHSXXXXXXXXXXXXATSKEPIPDPLLPRVVAF---IQEFPNFLRTVVQCARKTELALWSYLFESAGNPKDLFESCLMNNELDTAASYLIILQNIEHPLISQKQAILLLDAALNRSNWGLVSNLIRFLKNIVEEVFKYEHARNEFKMIEKGNYKSTKETYSSFN 2963
+ YP+ YV WPI+Y +I +GS + I+G HG A+Y K W L+ + E+ I V+ ++W + + G+ C E FE+ LY + +D+ + S I+ M++ D +LVV + D + +NE + ++Y+ ++ + + S L L + N +L+ Y LL+ +G L+L K S S+ + + F+ + F + I K ++F+ L +V I +ID E F RL ++D + + +N + N + L L N+++ +K+ S+ +LT VL+N LL++ + + VN + ++ I + FL IV+ LL ++ A+DL L Y N LE LL L +S+ D LL V +QEF F + V+ C RKTE W +F+ G PKDL + CL ++ +AA LII Q + + + + AL NW + + L +L ++ E + +++++G Y FN
Sbjct: 486 VEYPQPYVASEWPIRYVSIKDDGSLIAIAGLHGLAIYVCSKKTWFLYKDANMEQLISVTCPMIWCSQFLLAGVVC----ESNFELHLYKAKGPLDDRENLAKLSFTSTIVTMSVCDEYSLVVYTADNFLHHIRFDINELGR-LELDYLTSVNFAPIFTTPSRVRSITL--LLPKDLANIQPSDLLFYAVLLVLINGKLVLLSLKKQHSKELLYQCSMLAGDVEFYFINGSQEIPSLFHSIWIMTGKGLKLWLSFSEILS---SVLINTKNLIDGLPKFLNTSKRVSLENFH--RLSVEDLRSPSFVYKNGVDCNFDNTHLA---KLIKNVNISEKFQKEC-IDLESQGCLLT----------VLSNYGLLLTAYTQGHKNLVN-----KMEYAHIQIGVYPFLPEIVRALLLLDKREQAIDLVKTYGHLHYINFVLEKLLSSSLLTYNSSQR---DKLLYEVSLLFKDLQEFTTF-KIVLGCLRKTEAEYWPMIFKYFGEPKDLMKKCLETEDVKSAAECLIIWQIHQGSASCASTFLSIYEMALKIKNWDVCTELSSYLVSLDPE---KRLLKTALELLDEGPDSKDIRLYDQFN 1043
BLAST of RIC1 domain-containing protein vs. TrEMBL
Match: A0A1S3JAU3 (RAB6A-GEF complex partner protein 1 OS=Lingula unguis OX=7574 GN=LOC106171633 PE=4 SV=1) HSP 1 Score: 640.573 bits (1651), Expect = 0.000e+0 Identity = 387/1021 (37.90%), Postives = 571/1021 (55.93%), Query Frame = 3
Query: 21 MYYFFNCPKRIS---RHFVPSNITGIISSKSFALCAIFNSSQIIVFENKNNSIVAYYCRCEESLDIYGNSINLEWNSDGSLIAIGTDKGFLLIFSVKTVSQEVNVGYQNEKEFLEEGFINRQLS--------LFGE-IILLDVISFPY-----KISCICLYRDDLLVAIEDGTLSRIKWNGSLLYNQEFNLTSISFFSDLEFSKASNLSKNEAICRNIEWLPSLSGVIVLFKNGKSAFLHIPNHKLLSEQITGVWAENLRNVTCSAVNVKFRSIAYGLKIGEAVIYKTDEETGALRLQHRLKILSNEYPDADKVTGAVTYLKWSPDNFCLALCWEYIGFSLWSVQGSLLFSSLGNKAGI--------DMSLLSLDWGCEGYSLWLI-----------EKPD--------KSGKPAILIFQMAKSVLVVNPTKNNHEHXXXXXXXHIIF-----------GPRKLLSSSETNL---------------EYIPYPENYVTWNWPIKYAAIDLNGSRLVISGKHGFALYFFVSKKWRLFGNETQERTIEVSGGIVWYNHIVGLACFDNKEGKFEIRLYDSLQKIDNSLSTNHPVNSQILLMNIFDNTLVVLSIDGSIGLFEITLNEKSHDISMEY--IQTIPLENYIEFAACIVSFNLSSLHTEIGHNKDVDELIRYQSLLINYSGHLLLFQRDKSFSAPRTSDKSLNSQENSFFKLAFKNTLIAKQKITFTGPLVVAYNVEIMW-TPIIDEEFQSKRLKLDDWNAKIYTMENSLWLNCGSQGLRVWLPLNGGSNVTQVGEKKSKYSFLSKRIMLTFKIRNFYPLVVLNNEALLMSPMNEFSNDFVNTPTCLNLSFSSINKNRHIFLQHIVKELLRINLGIHALDLTFELKKLPYFNHSXXXXXXXXXXXXATSKEPIPDPLLPRVVAFIQEFPNFLRTVVQCARKTELALWSYLFESAGNPKDLFESCLMNNELDTAASYLIILQNIEHPLISQKQAILLLDAALNRSNWGLVSNLIRFLKNI 2864
MY+ PK +S H +P I+S++ +L AI + + ++ K + + R E S+ +G + EW D S+IAI T KG++L + V+ ++ NVG ++G R L L GE I L V Y ++C+ RDDLL++ G + RI+W+G N+ ++ F +DL+FS+AS + + ++E+ P L G + NG++AFL + + K QI GVWA+ + N +C VN K+R +A+GLK GE ++Y DE TGAL++ HRL + S +YPDA V G++T++KW+PD LA WE GF++WSV G+LLF SLG G+ + + S++WG EGY LW++ E P K IL Q KS L VNP +NH+HL L + P++ L S+ + I P NY+ NWPI+YAAID G + ++GK+G A Y ++KW+LFGNETQE+ + VSGG+ W+ V +AC++ + EIRLY K+DN +T V SQ+LL+N F + L+VL D I +F I + ++E IQ + + +I A + + L+SL TE + + +S+L+N +G LL+FQRD+S +A K+ +Q + FT P++VA VE +W TP ++ E K + +E +LWL CG+ G++VWLPL +V S + F+SKRIML F++ + YPL VL +A+++ N+ + +T NL F ++ + I+L HI+++LLR NLG HAL++ +LPYF H LELLLHEVLEEEATSK+PIPDPLLPRVVAFIQEFP FL+T+ CARKTE+ALW YLF + GNP+++FE C+++ +L TAASYLIILQN+E P++S++ A +LLD AL+ + W L +L+RFLK I
Sbjct: 1 MYFPVGWPKYLSIPQDHPLPP--IYIVSNRDRSLFAILTGNSLCIWFCKPCVEILSFRRSENSVSEFGENRTAEWRPDSSMIAITTSKGYILFYKVE---EDENVGNHQSIYVQKDG--RRSLPPRKATGDLLNGEGIPALKVSQLSYIQIQGGVTCLLCVRDDLLLSTYTGYIQRIRWDGCSNGQMSVNVKTVPFSTDLQFSRASTVQEENVNIPHMEYSPLLGGFATVLSNGRAAFLTVTSAKFEPHQIQGVWAQEVNNASCVGVNHKYRLMAFGLKNGEGMVYSIDEITGALQVSHRLAVSSKDYPDASHVVGSMTHIKWTPDGCALAAAWENGGFAVWSVFGALLFCSLGGDYGLSEDSFKHHSLHIKSMEWGAEGYHLWVMASRCDTSQVNGELPSDTNCNGEIKEENQDILQLQFVKSSLTVNPCMSNHQHLFLQGEDRLYVNNGLERTIHQTSPKQQLHPSQPGYPSNQAPSFLMGSKQWQVITVPSNYLGSNWPIRYAAIDRAGQCVAVAGKYGLAHYALFNRKWKLFGNETQEKDMVVSGGLTWWRDFVCVACYNILGQRDEIRLYPRSSKLDNVFATVTKVPSQVLLLNTFRDILIVLCADSHIMMFSIDRKNTQPNPTVEINKIQEVAIGGFIPHPASVTAITLTSLRTETASVRSKQPAVEAESILLNVAGRLLMFQRDRS------------------LHVAVKDGSKQRQ-LPFTSPVMVASAVENVWSTPRLNSE-------------KKHLVE-ALWLGCGAHGMKVWLPLFPRDDV-------SAHGFMSKRIMLPFRV-DIYPLAVLFEDAVILGATNDAT--CYDTGPSDNLPFLTLERTSQIYLHHILRQLLRRNLGHHALEIAHCCTELPYFPHCLELLLHEVLEEEATSKDPIPDPLLPRVVAFIQEFPEFLQTIAHCARKTEIALWHYLFNTVGNPREMFEECMLSGKLKTAASYLIILQNLEKPIVSRQHATMLLDTALDHNEWELARDLVRFLKAI 971
BLAST of RIC1 domain-containing protein vs. TrEMBL
Match: A0A210QAN5 (Protein RIC1-like OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT09064 PE=4 SV=1) HSP 1 Score: 595.504 bits (1534), Expect = 0.000e+0 Identity = 373/1008 (37.00%), Postives = 555/1008 (55.06%), Query Frame = 3
Query: 21 MYYFFNCPKRI---SRHFVPSNITGIISSKSFALCAIFNSSQIIVFENKNNSIVAYYCRCEESLDIYGNSINLEWNSDGSLIAIGTDKGFLLIFSVKTVSQEVNVGYQNEKEFLEEGFINRQLSLFGEIILLDVIS-------FPYKIS-----CICLYRDDLLVAIEDGTLSRIKWNGSLLYNQEFNLTSISFFSDLEFSKASNLSKNEAICRNIEWLPSLSGVIVLFKNGKSAFLHIPNHKLLSEQITGVWAENLRNVTCSAVNVKFRSIAYGLKIGEAVIYKTDEETGALRLQHRLKILSNEYPDADKVTGAVTYLKWSPDNFCLALCWEYIGFSLWSVQGSLLFSSLGNK-----AGIDM---SLLSLDWGCEGYSLWLIEKPDKSGKPA------------ILIFQMAKSVLVVNPTKNNHEHXXXXXXXHIIFGP----RKLLSSSETNL-------EYIPYPENYVTWNWPIKYAAIDLNGSRLVISGKHGFALYFFVSKKWRLFGNETQERTIEVSGGIVWYNHIVGLACFDNKEGKFEIRLYDSLQKIDNSLSTNHPVNSQILLMNIFDNTLVVLSIDGSIGLFEITL-NEKSHDI-SMEYIQTIPLENYIEFAACIVSFNLSSLHTEIG----HNKDVDELIRYQSLLINYSGHLLLFQRDKSFSAPRTSDKSLNSQENSFFKLAFKNTLIAKQKITFTGPLVVAYNVEIMWTPIIDEEFQSKRLKLDDWNAKIYTMENSLWLNCGSQGLRVWLPLNGGSNVTQVGEKKSKYSFLSKRIMLTFKIRNFYPLVVLNNEALLMSPMNEFSNDFVNTPTCLN--------LSFSSINKNRHIFLQHIVKELLRINLGIHALDLTFELKKLPYFNHSXXXXXXXXXXXXATSKEPIPDPLLPRVVAFIQEFPNFLRTVVQCARKTELALWSYLFESAGNPKDLFESCLMNNELDTAASYLIILQNIEHPLISQKQAILLLDAALNRSNWGLVSNLIRFLKNI 2864
MY+ PK + R+ P + +IS+ L A+ + ++ K + Y + + L G EW D S+IA+ T K ++ F V +++V + +EG + I D + F K+S C+C+ R++L+VA DG+L+R+KWNG+L L I D + +KA+ L+ ++ ++E+ P + G I++ +G+ F+ P+ ++ + GVW ++L++ C VN ++R +A+G G +Y +E G L L H+L + S +YPDA + G V LKW+PD LA+CW GFSLWSV GSLL SLG G+ + + SL+WG EGY LW++ + ++ + I+ Q KS L VNP NHEH+ L + +K +E++L + IP +Y+ NWPI+YAA+D +G L ++GK G A Y F+++KW+LFGNETQER + VSGG+ W+ + +AC++ + EI+ Y K+DN+ + + V SQ+LL+N F + L+V ID I L+ + N +S+ + + +Q + L NY+ C+ L+SL TE G HN E SLL++ +G LL+FQRD S P+ +D+ LN ++ + F P VVA NVE MWT + R K+ ME +LWL CG+QG++VWLPL ++ SF+SKRIML F++ + YPL VL +A+++ + N+P+ L F + + I+L HI+++LLR NLG++ALDL +L YF H LELLLHEVLE EAT+KEPIPDPLLPR+VAFIQEFP FL+TVV CARKTE+ALW YLF S GNPKDLF+ CL++ L+TAASYLIILQN+E P++S++ A LLLD++L + W L +L+RFLK I
Sbjct: 1 MYFPIGWPKYLKEAQRNSPP--LQYVISNCDRMLFAVLTEDTLSIWYCKPTVQIVNYTQSQRDLASLGGFCLAEWKPDSSMIAVMTTKQHVMFFKVDL---DISVANHHCLYVQQEGRAHPSKQDLNGIPDSDSVPAIKLTAVFQLKLSSQITWCLCV-REELVVATADGSLNRVKWNGTLNAKARLVLQDIPVSLDFQKTKAAKLTADDGHVVHMEYSPIIGGYIMVLSSGRGLFVMPPSSRVDNSVAQGVWVQDLKDANCLCVNHRYRLMAFGCCSGHGHVYVINELEGTLELSHKLTVSSRDYPDAAQTAGPVRCLKWTPDGTALAMCWRNGGFSLWSVFGSLLVCSLGGDYCFPNDGVRLFPPPIRSLEWGLEGYQLWMVCETVETEEEGYVGYHGHRDMSHIMQLQFVKSALTVNPCMANHEHVFLQGEDKLYMNTSDVSQKSTGRTESHLLVGNKHWQIIPISHSYLATNWPIRYAAVDRSGQYLAVAGKTGLAHYNFLNRKWKLFGNETQERDLVVSGGMAWWKDFICVACYNIVGQRDEIKCYPRSSKLDNTFAISTKVPSQVLLLNTFRDILIVFCIDSHIMLYNLERKNTQSNPLLDINKVQEVSLNNYVPHPVCVTGLALTSLKTEYGTRSHHNNKEAE-----SLLLSVAGKLLMFQRD--ISGPQVNDQKLNQTKH--------------KPPQFCPPSVVATNVENMWT--------TSRAN----QGKMQLME-ALWLGCGAQGMKVWLPL-------YPRDETKTLSFMSKRIMLPFRV-DIYPLAVLFEDAVILGAAGDALTYQHNSPSDAASPKKPTHYLPFCILERTSQIYLHHILRQLLRRNLGVNALDLARSCTELSYFPHVLELLLHEVLEAEATTKEPIPDPLLPRIVAFIQEFPEFLQTVVHCARKTEVALWPYLFSSVGNPKDLFQECLISGNLETAASYLIILQNLEKPIVSRQHATLLLDSSLEKGKWDLARDLVRFLKAI 960
BLAST of RIC1 domain-containing protein vs. TrEMBL
Match: A0A433SRT5 (RIC1 domain-containing protein OS=Elysia chlorotica OX=188477 GN=EGW08_020296 PE=4 SV=1) HSP 1 Score: 594.734 bits (1532), Expect = 0.000e+0 Identity = 371/1036 (35.81%), Postives = 558/1036 (53.86%), Query Frame = 3
Query: 21 MYYFFNCPKRISRHFVPSN----ITGIISSKSFALCAIFNSSQIIVFENKNNSIVAYYCRCEESLDIYGNSINLEWNSDGSLIAIGTDKGFLLIFSVKTVSQEVNVGYQNEKEF--LEEG--FINRQLSLFG----------EIILLDVISFPYKISCICLYRDDLLVAIEDGTLSRIKWNGSLLYNQEFNLTSISFFSDLEFSKASNLSKNEAICRNIEWLPSLSGVIVLFKNGKSAFLHIPNHKLLSEQITGVWAENLRNVTCSAVNVKFRSIAYGLKIGEAVIYKTDEETGALRLQHRLKILSNEYPDADKVTGAVTYLKWSPDNFCLALCWEYIGFSLWSVQGSLLFSSLGN--KAGID------MSLLSLDWGCEGYSLWLIEKPDKSGK----PA----------------------ILIFQMAKSVLVVNPTKNNHEHXXXXXXXHIIFGPRKLLS-----------------SSETNL----------EYIPYPENYVTWNWPIKYAAIDLNGSRLVISGKHGFALYFFVSKKWRLFGNETQERTIEVSGGIVWYNHIVGLACFDNKEGKFEIRLYDSLQKIDNSLSTNHPVNSQILLMNIFDNTLVVLSIDGSIGLFEITLN--EKSHDISMEYIQTIPLENYIEFAACIVSFNLSSLHTEIGHNKDVDELIRYQSLLINYSGHLLLFQRDKSFSAPRTSDKSLNSQENSFFKLAFKNTLIAKQKITFTGPLVVAYNVEIMWTPIIDEEFQSKRLKLDDWNAKIYTMENSLWLNCGSQGLRVWLPLNGGSNVTQVGEKKSKYSFLSKRIMLTFKIRNFYPLVVLNNEALLMSPMNEF------SNDFVNTPTCLNLSFSSINKNRHIFLQHIVKELLRINLGIHALDLTFELKKLPYFNHSXXXXXXXXXXXXATSKEPIPDPLLPRVVAFIQEFPNFLRTVVQCARKTELALWSYLFESAGNPKDLFESCLMNNELDTAASYLIILQNIEHPLISQKQAILLLDAALNRSNWGLVSNLIRFLKNIV 2867
MY+ PKR+ PS I+ I+SS L A+ + + ++ +K + + C++ G+ EW D SL+AI T + ++ V EV+ +N ++EG I ++++ G ++ + +S ISC RD+L+VA DG L+R++W G+ +L I +DL+ +A+ LS + +E+ P+L G ++ +G++ F+ P+ + GVWA+ + + AVN ++R IA+G G+ ++Y DE GAL + HRL I S E+PDA + G VT +KW+PD LAL W+ G SLWSV GSLL +LG + D ++S++WG EGY LW++ K K P +L FQ KS L VNP +NHEH+ L + +S SS N+ + IP +Y+ NWPI+YA++D G + ++GK GFA Y S+KW+LFGNETQER + VSGGI W+ V LACF+ + + EIR Y K+DN+ + V SQ+LL+N F + L+ D + +F + + + + + +Q I L ++I C+ L+SL +E + K +S+L++ SG LL+FQRD+S P+ ++ KN + + F P VVA +VE +WT + R + K+ ME ++WL CGS G++VWLPL ++ ++F+S+RIML F++ + YPL VL +A+++ + S+ + N +++ F ++ + I+L HI+++LLR NLG++ALDL K+L YF H LELLLHEVLE EATSKEPIPDPLLPRVVAFIQEFP FL+T+V CARKTE+ALW YLF + GNPKDLFE CL+N +L+TAA+YLIILQN+E P++S++ A +LLD+AL+R W L +L+RFLK I
Sbjct: 1 MYFPLGWPKRLK---TPSGDSVLISHIVSSCDRMLFAVISKKTLSIWYSKPCVQIVTFTPCQKLFSEIGHFCKGEWKPDSSLVAITTQQNVVVFIKV-----EVDTSVKNHHCLYVMQEGKTPITPKININGILDSDSVPAIKLTYMAHVSLQSHISCFLSVRDELVVATIDGCLNRLRWTGNKNEKATLHLNDIPVSADLQQFRATRLSSGNSHVCEMEYSPTLGGYSMVLSSGRAVFVIPPSSRGEKTNAHGVWAQEVNDAATVAVNHRYRLIAFGCFSGDGIVYHLDEAVGALEISHRLVISSKEFPDAGLIAGQVTCMKWTPDGTALALAWKNGGLSLWSVFGSLLLCTLGGDYSSSTDSGSLYPAPIVSMEWGLEGYHLWMVSKSVAQTKNGSDPGDNKHREEGDSESINAETNYCTQLLQFQFVKSALTVNPCMSNHEHVFLQGEDKLYMSTGDTMSRSNLHHNHSQQQKPNSGSSSINMGAGYIGNKQWQVIPISHSYLASNWPIRYASVDRAGQCVAVAGKTGFAHYALFSRKWKLFGNETQERDMVVSGGITWWKDFVCLACFNIQGQRDEIRCYPRTAKLDNTFAKVLQVQSQVLLLNTFRDMLITFCADSHVAMFSLERKNVQSNPSVQITKVQEISLTSFIPHPLCVAGLTLTSLMSESVNPKLHPSSKEAESMLVSVSGKLLMFQRDRS--GPQIKEE--------------KN---KHRPVPFCNPSVVATSVENLWT--------TTRANV----GKVQLME-AMWLGCGSHGMKVWLPLFPR-------DEGKAHNFMSRRIMLPFRV-DIYPLAVLFEDAVILGAACDVVSYTFSSSSYKN----MDMPFCTLERTSQIYLHHILRQLLRRNLGVNALDLARSCKELTYFPHVLELLLHEVLEAEATSKEPIPDPLLPRVVAFIQEFPEFLQTIVHCARKTEVALWPYLFSTVGNPKDLFEMCLLNKDLETAATYLIILQNLEKPIVSRQLATILLDSALDRGTWELCRDLVRFLKAIA 984
BLAST of RIC1 domain-containing protein vs. TrEMBL
Match: V4A9V7 (RIC1 domain-containing protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_123886 PE=4 SV=1) HSP 1 Score: 588.956 bits (1517), Expect = 1.007e-180 Identity = 399/1122 (35.56%), Postives = 587/1122 (52.32%), Query Frame = 3
Query: 21 MYYFFNCPKRISRHFVPSN-ITGIISSKSFALCAIFNSSQIIVFENKNNSIVAYYCRCEESLDIYGNSINLEWNSDGSLIAIGTDKGFLLIFSVK---TVSQEVNVGYQNE------KEFLEEGFINRQLSLFGEIILLDVISFPYKISCICLYRDDLLVAIEDGTLSRIKWNGSLLYNQEFNLTSISFFSDLEFSKASNLSKNEAICRNIEWLPSLSGVIVLFKNGKSAFLHIPNHKLLSEQITGVWAENLRNVTCSAVNVKFRSIAYGLKIGEAVIYKTDEETGALRLQHRLKILSNEYPDADKVTGAVTYLKWSPDNFCLALCWEYIGFSLWSVQGSLLFSSLGNKAGI--DMSLL------SLDWGCEGYSLWLIEKPDKSGKP----------------AILIFQMAKSVLVVNPTKNNHEHXXXXXXXHIIFGPRKL-LSSSET--------------------NLEYIPYPENYVTWNWPIKYAAIDLNGSRLVISGKHGFALYFFVSKKWRLFGNETQERTIEVSGGIVWYNHIVGLACFDNKEGKFEIRLYDSLQKIDNSLSTNHPVNSQILLMNIFDNTLVVLSIDGSIGLFEITL--NEKSHDISMEYIQTIPLENYIEFAACIVSFNLSSLHTEIGHNKDVDELIRYQSLLINYSGHLLLFQRDKSF-SAPRTSDKSLNSQENSFFKLAFKNTLIAKQKITFTGPLVVAYNVEIMWTPIIDEEFQSKRLKLDDWNAKIYTMENSLWLNCGSQGLRVWLPLNGGSNVTQVGEKKSKYSFLSKRIMLTFKIRNFYPLVVLNNEALLMSPMNE---FSNDFVNTPTC-------LNLSFSSINKNRHIFLQHIVKELLRINLGIHALDLTFELKKLPYFNHSXXXXXXXXXXXXATSKEPIPDPLLPRVVAFIQEFPNFLRTVVQCARKTELALWSYLFESAGNPKDLFESCL-MNNELDTAASYLIILQNIEHPLISQKQAILLLDAALNRSNWGLVSNLIRFLKNIVEEVFKYEHARNEFKMIEKGNYKSTKETYSSFNTKKRYRSGGGIGMATSRQYSTGK------IKDIEILKSSKSAQNGNIDENCYDDLVFDSVGSK-INTLLSPN 3158
MY+ PK + V S+ I I+SS L A+ + + ++ +K + + + +++L +G + EW D S+IA+ T ++ + V+ +V + Q+E F G ++ ++I ++ I+C RD++L++ DG L+R+KWNG+ +L+ I DL+ +AS L++++ N+E+ P+L G ++ +GK+ FL P+ + V A++L + AVN ++R IA+G GE ++Y DE GAL + H+L I S E+PD + G+V+ LKW+PD LAL W+ GFSLWSV G+LL +LG D SLL SL+WG EGY LW++ + K ++ FQ KS L VNP NHEH+ + G KL +S+S+T N + IP NY NWPI+Y+A+D G + ++GK GFA Y +KW+LFGNETQER + VSGGI W+ + LAC++ + EIR Y K+DN+ + V SQ+LL+N F +TL++ D + LF I + + + + IQ + L N+I C+ L+SL +E K +S+L+N SG LL+FQRD+S S P D+ KL + + F P VVA +VE +W SK + K+ ME +LWL CG+ G++VWLPL + E K+ ++F+SKRIML F + + YPL VL +A+++ ++ + N F +P +L F + + I+L HI+++LLR NLG HALDL +LPYF H LELLLH VLE EATSK PIPDPLLPRVVAFIQEFP FL+TVV CARKTE+ALW YLF + GNPKDLFE CL + L+TAASYLIILQN+E+P +S++ A LLL+A+L + W L +L+RFL+ I + +M NY+S R+ G A SR K + D +++ S K Q +E + + D + S+ LLS N
Sbjct: 1 MYFPIGWPKYLKIDEVSSSPIRYIVSSCDRMLFAVISDDCLSLWYSKPCVKIVTHSQSKKTLAKFGTYMAAEWKPDSSMIAVITSNHHVVFYRVEIDISVPNHHCLYVQHEGKTPQNPRFNINGILDSDSVPAIKLIFETSVTLTTDIACCLCVRDEILISTVDGFLNRLKWNGNKNEKATLHLSDIPVSVDLQQFRASKLTESDGHAVNMEYSPTLGGYSLVLSSGKALFLIPPSTRAERATAHAVRAQDLSDAVTVAVNHRYRLIAFGCLTGEGIVYTIDEAVGALEVSHKLIISSKEFPDVGNIAGSVSCLKWTPDGTALALTWKNGGFSLWSVFGALLVCTLGGDYVFQKDSSLLYPYPVTSLEWGLEGYHLWMVCESATDSKSHTEDDLPSSSIESSKSELIQFQFVKSALSVNPCVGNHEHV-------FLQGEDKLYMSTSDTVSRHSPQPKGEQSNIDIGNKNWQVIPISHNYTAANWPIRYSAVDRAGQCIAVAGKTGFAHYALFHRKWKLFGNETQERDMVVSGGITWWKDFICLACYNIPGQQDEIRFYPRNCKLDNTFAHVCKVPSQVLLLNTFKDTLIIFCADSHVMLFGIERKNTQPNPTVVVHKIQEVSLSNFIPHPLCVAGLTLTSLTSESLLTKAQHTAKEAESMLLNVSGKLLMFQRDRSAQSKPSKGDER---------KL---------KPLPFYSPSVVATSVENIWA-------TSKAN-----SGKVQLME-ALWLGCGAHGMKVWLPLYPRN------EGKA-HNFMSKRIMLPFNV-DIYPLAVLFEDAVILGAASDAVFYENSFSASPPSNLDGGKIAHLPFCILERTSQIYLHHILRQLLRRNLGFHALDLARCCTELPYFPHVLELLLHGVLEAEATSKAPIPDPLLPRVVAFIQEFPEFLQTVVHCARKTEVALWPYLFSTVGNPKDLFEECLKVGGNLETAASYLIILQNLENPKVSRQHATLLLEASLESNCWELCRDLVRFLQAIDPNDVDSPPHGSVNRMSGSSNYQSI-------------RTASVAGDAISRDVPKPKEKLKQTVSDSKVISSKKPLQRTKSNEASAEKVYIDMILSRHARKLLSTN 1063
BLAST of RIC1 domain-containing protein vs. TrEMBL
Match: R7TQG5 (RIC1 domain-containing protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_227272 PE=4 SV=1) HSP 1 Score: 588.956 bits (1517), Expect = 2.464e-180 Identity = 361/984 (36.69%), Postives = 541/984 (54.98%), Query Frame = 3
Query: 87 IISSKSFALCAIFNSSQIIVFENKNNSIVAYYCRCEESLDIYGNSINLEWNSDGSLIAIGTDKGFLLIFSVKTVSQEVNVGYQNEKEFLEEGFINRQLSLFGEIILLDVI-----------SFPYKISCICLYRDDLLVAIEDGTLSRIKWNGSLLYNQEFNLTSISFFSDLEFSKASNLSKNEAICRNIEWLPSLSGVIVLFKNGKSAFLHIPNHKLLSEQITGVWAENLRNVTCSAVNVKFRSIAYGLKIGEAVIYKTDEETGALRLQHRLKILSNEYPDADKVTGAVTYLKWSPDNFCLALCWEYIGFSLWSVQGSLLFSSLGNKAGIDMS---------LLSLDWGCEGYSLWLI-EKPD-----------KSGKPAILIFQMAKSVLVVNPTKNNHEHXXXXXXXHIIFGPRK----LLSSSE--------------TNLEYIPYPENYVTWNWPIKYAAIDLNGSRLVISGKHGFALYFFVSKKWRLFGNETQERTIEVSGGIVWYNHIVGLACFDNKEGKFEIRLYDSLQKIDNSLSTNHPVNSQILLMNIFDNTLVVLSIDGSIGLFEI-TLN-EKSHDISMEYIQTIPLENYIEFAACIVSFNLSSLHTEIGHNKDVDELIRYQSLLINYSGHLLLFQRDKSFSAPRTSDKSLNSQENSFFKLAFKNTLIAKQK-ITFTGPLVVAYNVEIMWTPIIDEEFQSKRLKLDDWNAKIYTMENSLWLNCGSQGLRVWLPLNGGSNVTQVGEKKSKYSFLSKRIMLTFKIRNFYPLVVLNNEALLMSPMNE-----FSNDFVNTPTCLNLSFSSINKNRHIFLQHIVKELLRINLGIHALDLTFELKKLPYFNHSXXXXXXXXXXXXATSKEPIPDPLLPRVVAFIQEFPNFLRTVVQCARKTELALWSYLFESAGNPKDLFESCLMNNELDTAASYLIILQNIEHPLISQKQAILLLDAALNRSNWGLVSNLIRFLKNI 2864
I S++ L A+ S I ++ K + + R + S+ +G ++ +W D S+IAI T KG++L + V+ + N +KE E F +Q S+ E+ D I P ++ + R++L+VA G L RI W+G + + L+SI F +DL+ S+AS L ++ P L G V+ NG++AF+ K I GVWA+ + T +A+N K+ +A+G + E ++Y DE TGAL + HRL + S E+PDA + GAV+ LKW+PD LA+ W GFSLWSV G+LL S+G ++G +S + SL+WGCEGY LWL+ ++PD PA+ KS L +NP NHEHL L + P + L SS + +P P Y+ NWPI++AA++ G + I+GK G A Y S+KW+LFGNETQER + V+GG++W+ V AC++ + + EIR Y K+DN+ + V SQI+L+N F + L+VL D I ++ I +N + + + + IQ + + N+I A +V+ L+S+ T+ G ++ +S+++N +G LLLFQRD+ S P+ K+ AK + + F P++VA VE MW + N + + +LWL CG+ G++VWLPL + ++ K F+SKRIM+ F + + YPL +L +++ +E SND + + + + H++L HI+++LL+ +LG+HAL++ LPYF H LELLLHEVLEEEATSKEPIPDPLLPRVVAF++EF +FL+TV CARK+E+ALW YLF G PKDLFE CL+ +L+TAASYLIILQN+E P+++++ A LLLDAAL +W L +L+RFL I
Sbjct: 26 ICSNQDRLLFAVLTHSSISIWYCKPAVQIVCFRRSDNSVVEFGMNVCAKWKPDSSMIAIVTSKGYILFYQVEVELSKKNASLYIQKE--ERSFGGKQDSI--ELNNSDCIPALKLSQVAYSQVPGGVTSLVCLREELMVATRRGLLQRIHWDGIVNSDMTIELSSIPFSADLQHSRASMLDDRGIYVSRQDYSPLLGGFAVVLSNGRAAFITANTLKFEPSNIVGVWAQEVTEATTAAINHKYTLMAFGCQNAEGIVYHLDELTGALLVSHRLVVSSKEFPDAQTICGAVSELKWTPDGTALAMVWRKGGFSLWSVFGALLVHSMGVESGGSISDDLNTQLLRIQSLEWGCEGYHLWLLTDRPDNPSPSPPGKPSADPHPALHQLNFVKSALALNPCAGNHEHLFLQGEDKLYLNPEEGMPHLHKSSALPDSLAAAAAFIGNKQWQIVPLPHTYLAHNWPIRFAAVNAAGHCVAIAGKTGLAHYALYSRKWKLFGNETQERDMIVTGGLIWWKDFVCTACYNLLDQRDEIRFYPRDSKLDNTFAHIVRVPSQIMLINTFRDLLIVLCADCHIMIYSILRVNVQPNPTVQVSKIQEVAIGNFIPHPANVVALTLTSIRTDTGPASAPSDIPDAESIVVNVAGRLLLFQRDR--SGPQ-----------------LKSPKEAKDRPLPFCSPVMVASAVESMWL-------------CNHRNGRKQHLTEALWLCCGAAGVKVWLPL-----YPKEEQQNKKRGFMSKRIMIPFHV-DIYPLALLFEAGIMLGASSESLSYNASNDEI-------WPYLQLERTSHVYLHHILRQLLKRHLGVHALEIARTCTDLPYFLHVLELLLHEVLEEEATSKEPIPDPLLPRVVAFVEEF-DFLQTVAHCARKSEVALWQYLFSIVGTPKDLFEECLLEGKLETAASYLIILQNLEQPIVARQHATLLLDAALEHRHWDLARDLVRFLGAI 959
BLAST of RIC1 domain-containing protein vs. Ensembl Cavefish
Match: RIC1 (RIC1 homolog, RAB6A GEF complex partner 1 [Source:NCBI gene;Acc:103035554]) HSP 1 Score: 544.273 bits (1401), Expect = 2.094e-167 Identity = 337/985 (34.21%), Postives = 514/985 (52.18%), Query Frame = 3
Query: 117 AIFNSSQIIVFENKNNSIVAYYCRCEESLDIYGNSINLEWNSDGSLIAIGTDKGFLLIFSVKTVSQEVNVGYQNEKEFLEE-------------GFINRQLSLFGEIILLDVISFPYKISCICLYRDDLLVAIEDGTLSRIKWNGSLLYNQEFNLTSISFFSDLEFSKASN-LSKNEAICRNIEWLPSLSGVIVLFKNGKSAFLHIPNHKLLSEQITGVWAENLRNVTCSAVNVKFRSIAYGLKIGEAVIYKTDEETGALRLQHRLKILSNEYPDADKVTGAVTYLKWSPDNFCLALCWEYIGFSLWSVQGSLLFSSLGNKAGI--------DMSLLSLDWGCEGYSLWLIEKPDKS-------GKPAILIFQMAKSVLVVNPTKNNHEHXXXXXXXHI---------IFGP-RKLLSSSETNLEYIPYP--------------------ENYVTWNWPIKYAAIDLNGSRLVISGKHGFALYFFVSKKWRLFGNETQERTIEVSGGIVWYNHIVGLACFDNKEGKFEIRLYDSLQKIDNSLSTNHPVNSQILLMNIFDNTLVVLSIDGSIGLFEITLNEKSHD--ISMEYIQTIPLENYIEFAACIVSFNLSSLHTEIGHN-KDVDELIRYQSLLINYSGHLLLFQRDKSFSAPRTSDKSLNSQENSFFKLAFKNTLIAKQKITFTGPLVVAYNVEIMWTPIIDEEFQSKRLKLDDWNAKIYTMENSLWLNCGSQGLRVWLPLNGGSNVTQVGEKKSKYSFLSKRIMLTFKIRNFYPLVVLNNEALLMSPMNEF-------SNDFVNTPTCLNLSFSSINKNRHIFLQHIVKELLRINLGIHALDLTFELKKLPYFNHSXXXXXXXXXXXXATSKEPIPDPLLPRVVAFIQEFPNFLRTVVQCARKTELALWSYLFESAGNPKDLFESCLMNNELDTAASYLIILQNIEHPLISQKQAILLLDAALNRSNWGLVSNLIRFLKNI 2864
A+ +Q+ ++ ++ + +V Y ++ +G EW D S+IA+ G++L+F + +G ++K E G+ Q + + + + I+ + ++DLLV DG L + W+G + NL +ISF DL+ S+ L N R++E+ +L G V+F +G+ F+ + +E + GVWA ++ + TC AVN K+R +A+G G ++Y D TG+++L H+L++ YPD TG V ++WSPD + + WE G SLWSV G+ L +LG + + S+ WG EGY LW+I + + +IL FQ KS L VNP +N E +LL + + P L SS + + P Y+ NWPI++AAID G L ++G+ GFA Y ++KW+LFGN TQE+++ V+GG+ W+N V +AC++ + + E+RLY +DN+ ++ ++++ LL+N+F N +++ D SI L+ I + S + S+E +Q + + YI +VS L+S+ TE G + K + +S+L+N +G L++ QRD+S R D N K+ + F P+V+A VE +WT N K + +LWL+CG G++VWLPL + + +SFLS+RIML F + N YPL VL +AL++ NE ++ P F ++ + I+L H++++LL NLG AL L LPYF+H LEL++H VLEEEATS+EPIPDPLLP V FI EFP FLRT+V CARKTE ALW+YLF + GNPKDLFE CLM +LDTAASYLIILQN+E P +S++ A LL + AL + W L ++IRFLK I
Sbjct: 34 AVLAHTQLSIWFSRPSVLVVSYIESAKAAAQFGFYQQAEWKPDDSMIAVAAANGYVLLFDI--------IGGGDDKYLYEPVYPKGSPRVKVTPGYKEEQCAPALSLEMKKPVDLEAPITSLQSLQEDLLVCTADGYLHMLHWDGVRNGRRAVNLCTISFSLDLQSSRGGPCLDLNGVHVRDMEYCSTLDGFAVVFDDGRLGFMTPTASRFSTEHLQGVWAADVTDGTCVAVNNKYRLMAFGCASGSVLVYMIDNTTGSMQLSHKLELTPKHYPDIWNKTGPVKMIRWSPDCSVVMVTWECGGLSLWSVFGAHLICTLGEDFAYRLDGTKKDPLKISSMSWGAEGYHLWVISSSEGGVDESTELRQASILQFQFIKSALTVNPCTSNQEQVLLHGEDRLFLTCGDAAQVHSPVEPLRDSSPMHRPHTTPPLSQGLSTLLGHKHWHVVQIHSTYLESNWPIRFAAIDSAGQCLAVAGRRGFAHYSLFTRKWKLFGNITQEQSMTVTGGLAWWNDFVVVACYNFIDQQEELRLYHRSCNLDNAFASITKLHAETLLLNVFKNMVILFRTDCSICLYSIEKKQDSPNPFASVELLQEVSMSRYIPHPGLVVSVTLTSVRTETGISLKAPQQACTAESILLNLAGQLIMLQRDRSGPQVREKDAVPNQ----------------KKLLPFCPPVVLAQCVENVWTTCRT-------------NRKKRHLVEALWLSCGEAGMKVWLPLFPR-------DHRKPHSFLSRRIMLPF-LLNIYPLAVLFEDALVLGATNETLLYDNLGAHSSSEEPLESMFPFCTVERTSQIYLHHLLRQLLVRNLGEQALMLAQSCSSLPYFSHVLELMVHVVLEEEATSREPIPDPLLPTVAKFITEFPLFLRTIVHCARKTEFALWNYLFAAVGNPKDLFEECLMAQDLDTAASYLIILQNMEVPAVSRQHATLLFNTALEQGKWDLCRHMIRFLKAI 973
BLAST of RIC1 domain-containing protein vs. Ensembl Cavefish
Match: RIC1 (RIC1 homolog, RAB6A GEF complex partner 1 [Source:NCBI gene;Acc:103035554]) HSP 1 Score: 493.426 bits (1269), Expect = 3.283e-149 Identity = 320/955 (33.51%), Postives = 496/955 (51.94%), Query Frame = 3
Query: 117 AIFNSSQIIVFENKNNSIVAYYCRCEESLDIYGNSINLEWNSDGSLIAIGTDKGFLLIFSVKTVSQEVNVGYQNEKEFLEE-------------GFINRQLSLFGEIILLDVISFPYKISCICLYRDDLLVAIEDGTLSRIKWNGSLLYNQEFNLTSISFFSDLEFSKASN-LSKNEAICRNIEWLPSLSGVIVLFKNGKSAFLHIPNHKLLSEQITGVWAENLRNVTCSAVNVKFRSIAYGLKIGEAVIYKTDEETGALRLQHRLKILSNEYPDADKVTGAVTYLKWSPDNFCLALCWEYIGFSLWSVQGSLLFSSLGNKAGI--------DMSLLSLDWGCEGYSLWLIEKP----DKSG---KPAILIFQMAKSVLVVNPTKNNHEHXXXXXXXHIIF---GPRKLLSSSETNLEYIPYPENYVTWNWPIKYAAIDLNGSRLVISGKHGFALYF---FVSKKWRLFGNETQERTIEVSGGIVWYNHIVGLACFDNKEGKFEIRLYDSLQKIDNSLSTNHPVNSQILLMNIFDNTLVVLSIDGSIGLFEITLNEKSHD--ISMEYIQTIPLENYIEFAACIVSFNLSSLHTEIGHN-KDVDELIRYQSLLINYSGHLLLFQRDKSFSAPRTSDKSLNSQENSFFKLAFKNTLIAKQKITFTGPLVVAYNVEIMWTPIIDEEFQSKRLKLDDWNAKIYTMENSLWLNCGSQGLRVWLPLNGGSNVTQVGEKKSKYSFLSKRIMLTFKIRNFYPLVVLNNEALLMSPMNE-FSNDFVNTPTCLNLSFSSINKNRHIFLQHIVKELLRINLGIHALDLTFELKKLPYFNHSXXXXXXXXXXXXATSKEPIPDPLLPRVVAFIQEFPNFLRTVVQCARKTELALWSYLFESAGNPKDLFESCLMNNELDTAASYLIILQNIEHPLISQKQAILLLDAALNRSNWGLVSNLIRFLKNI 2864
A+ +Q+ ++ ++ + +V Y ++ +G EW D S+IA+ G++L+F + +G ++K E G+ Q + + + + I+ + ++DLLV DG L + W+G + NL +ISF DL+ S+ L N R++E+ +L G V+F +G+ F+ + +E + GVWA ++ + TC AVN K+R +A+G G ++Y D TG+++L H+L++ YPD TG V ++WSPD + + WE G SLWSV G+ L +LG + + S+ WG EGY LW+I D+S + +IL FQ KS L VNP +N E +LL + ++ S E + P + T P+ G ++ KH + ++ W + +E+++ V+GG+ W+N V +AC++ + + E+RLY +DN+ ++ ++++ LL+N+F N +++ D SI L+ I + S + S+E +Q + + YI +VS L+S+ TE G + K + +S+L+N +G L++ QRD+S R D N K+ + F P+V+A VE +WT N K + +LWL+CG G++VWLPL + + +SFLS+RIML F + N YPL VL +AL++ NE D + P F ++ + I+L H++++LL NLG AL L LPYF+H LEL++H VLEEEATS+EPIPDPLLP V FI EFP FLRT+V CARKTE ALW+YLF + GNPKDLFE CLM +LDTAASYLIILQN+E P +S++ A LL + AL + W L ++IRFLK I
Sbjct: 34 AVLAHTQLSIWFSRPSVLVVSYIESAKAAAQFGFYQQAEWKPDDSMIAVAAANGYVLLFDI--------IGGGDDKYLYEPVYPKGSPRVKVTPGYKEEQCAPALSLEMKKPVDLEAPITSLQSLQEDLLVCTADGYLHMLHWDGVRNGRRAVNLCTISFSLDLQSSRGGPCLDLNGVHVRDMEYCSTLDGFAVVFDDGRLGFMTPTASRFSTEHLQGVWAADVTDGTCVAVNNKYRLMAFGCASGSVLVYMIDNTTGSMQLSHKLELTPKHYPDIWNKTGPVKMIRWSPDCSVVMVTWECGGLSLWSVFGAHLICTLGEDFAYRLDGTKKDPLKISSMSWGAEGYHLWVISSSEGGVDESTELRQASILQFQFIKSALTVNPCTSNQEQVLLHGEDRLFLTCGDAAQVHSPVEPLRDSSPMHRPHTTP--PLS------QGLSTLLGHKHWHVVQIHSTYLESNWPI-----REQSMTVTGGLAWWNDFVVVACYNFIDQQEELRLYHRSCNLDNAFASITKLHAETLLLNVFKNMVILFRTDCSICLYSIEKKQDSPNPFASVELLQEVSMSRYIPHPGLVVSVTLTSVRTETGISLKAPQQACTAESILLNLAGQLIMLQRDRSGPQVREKDAVPNQ----------------KKLLPFCPPVVLAQCVENVWTTCRT-------------NRKKRHLVEALWLSCGEAGMKVWLPLFPR-------DHRKPHSFLSRRIMLPF-LLNIYPLAVLFEDALVLGATNETLLYDNLGEPLESMFPFCTVERTSQIYLHHLLRQLLVRNLGEQALMLAQSCSSLPYFSHVLELMVHVVLEEEATSREPIPDPLLPTVAKFITEFPLFLRTIVHCARKTEFALWNYLFAAVGNPKDLFEECLMAQDLDTAASYLIILQNMEVPAVSRQHATLLFNTALEQGKWDLCRHMIRFLKAI 930
BLAST of RIC1 domain-containing protein vs. Ensembl Nematostella
Match: EDO36179 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SJG9]) HSP 1 Score: 494.967 bits (1273), Expect = 3.807e-154 Identity = 309/863 (35.81%), Postives = 461/863 (53.42%), Query Frame = 3
Query: 453 RDDLLVAIEDGTLSRIKWNGSLLYNQEFNLTSISFFSDLEFSKASNLSKNEAIC-RNIEWLPSLSGVIVLFKNGKSAFLHIPNHKLLSEQITGVWAENLRNVTCSAVNVKFRSIAYGLKIGEAVIYKTDEETGALRLQHRLKILSNEYPDADKVTGAVTYLKWSPDNFCLALCWEYI---GFSLWSVQGSLLFSSLGNKAGIDMSLL--------SLDWGCEGYSLWLIEKPDKSGKPA----------ILIFQMAKSVLVVNPTKNNHEHXXXXXXXHIIFGPRKLLSSSETNLE-----------------------------YIPYPENYVTWNWPIKYAAIDLNGSRLVISGKHGFALYFFVSKKWRLFGNETQERTIEVSGGIVWYNHIVGLACFDNKEGKFEIRLYDSLQKIDNSLSTNHPVNSQILLMNIFDNTLVVLSIDGSIGLFEITLNE---KSHDISMEYIQTIPLENYIEFAACIVSFNLSSLHTEIGHNKDVDELIRYQSLLINYSGHLLLFQRDKSFSAPRTSDKSLNSQENSFFKLAFKNTLIAKQKITFTGPLVVAYNVEIMWTPIIDEEFQSKRLKLDDWNAKIYTMENSLWLNCGSQGLRVWLPLNGGSNVTQVGEKKSKYSFLSKRIMLTFKIRNFYPLVVLNNEALLMSPMNEFSNDFVNTPTCLNLS-----FSSINKNRHIFLQHIVKELLRINLGIHALDLTFELKKLPYFNHSXXXXXXXXXXXXATSKEPIPDPLLPRVVAFIQEFPNFLRTVVQCARKTELALWSYLFESAGNPKDLFESCLMNNELDTAASYLIILQNIEHPLISQKQAILLLDAALNRSNWGLVSNLIRFLKNI 2864
RD+L V +G L R W+G + + + SI F +D E ++A L +E +C R +E+ P L G V+ +G+ FL + ++ GVWA++L TC AVN ++R I +G GE+ +Y D+ TG L L H+L + S +YPDA TG V L W+PD +A+ W + G +LWSV GSLL +LG G S+ WG EGY+L ++ + +G A I+ Q KS L VNP +NH HL L S + ++S S N I P +Y+ NWP++YAA+D +G + ++GK G A Y +++W+LFGN +QE++I GG+ W+ + + C++ E+R Y + +DN+ +T+ + + L+N+F + L+V S D + + + ++ S I + +Q L N++ ++ L+S VD L ++L+ N G LL+ Q+DK+ + DK S++ ++F+ P+V+A VE WT D K + ME +LWL CG+QG++VWLPL G++ + +FLSKRIML F++ N YPL VL +A+++ NE +P +LS F ++ + ++L H++++LLR NLG AL + LPYF H LEL+LHEVLEEEAT+ EPIPD LLPRVV FIQEFP +L TVV CARKTE+ALWSYLF + GNP+DLF+ CL + L+TAASYLIILQN+E P +S++ A +LLD AL S W + +L+RFL+ I
Sbjct: 6 RDELFVCSGNGLLQRFTWDGLIEAEETIPIHSIPFTNDFESARAVPL-DHEGVCFRAMEYSPLLGGFAVVLADGRGGFLSAESANFEPSEVIGVWAKDLTCATCCAVNHRYRLIVFGCTNGESHVYGFDDLTGGLILSHKLLLSSKDYPDAIHSTGGVQCLAWTPDGSAIAVSWSWASHGGLALWSVFGSLLMCTLGGDYGKSQEAFLHNPFHVKSMAWGAEGYNLVMVSAEEDNGSTAHSVILLHPGDIMQLQFVKSTLAVNPCMSNHNHLFLQSEECLYLNTGDMVSDSAENFRNCQGTGGSTSPLMTSSVGPSTLVSNKQWVVIQIPMSYLEANWPVRYAAVDKSGIHVAVAGKAGVAHYALNTRRWKLFGNISQEQSITCRGGLAWWKDFLIVPCYNFNSTNDEVRFYPRINNLDNAFATHVRLAAPAFLVNVFRDLLLVYSSDCRVLFYSMERSQTGPSSASIQVTRLQEFSLVNHVPHPLSVIHLTLTS------QVDGVDGLGGVEALIANVGGWLLMLQKDKAIA-----DKDKKSKQ-----------------VSFSSPVVLASCVENCWT---------SSTSCPD---KRHLME-ALWLGCGAQGMKVWLPLFPGND-------QRPPNFLSKRIMLPFQL-NIYPLAVLFQDAVVLGAANEPMPLDCLSPNPASLSPQPFPFCTLERTTQVYLHHVLRQLLRRNLGQQALKIANTCTDLPYFPHVLELMLHEVLEEEATASEPIPDALLPRVVEFIQEFPQYLETVVHCARKTEVALWSYLFSAVGNPRDLFKECLSSGRLETAASYLIILQNLEKPSVSKQHATILLDKALELSRWEISKDLVRFLRCI 818
BLAST of RIC1 domain-containing protein vs. Ensembl Medaka
Match: RIC1 (RIC1 homolog, RAB6A GEF complex partner 1 [Source:NCBI gene;Acc:101155531]) HSP 1 Score: 531.176 bits (1367), Expect = 4.335e-163 Identity = 355/1116 (31.81%), Postives = 565/1116 (50.63%), Query Frame = 3
Query: 21 MYYFFNCPKRI----SRHFVPSNITGIISSKSFALCAIFNSSQIIVFENKNNSIVAYYCRCEESLDIYGNSINLEWNSDGSLIAIGTDKGFLLIFSVKTVSQEVNVGYQ------NEKEFLEEGFINRQLSLFGEIILLDVISFPYKISCICLYRDDLLVAIEDGTLSRIKWNGSLLYNQE-FNLTSISFFSDLEFSKAS-NLSKNEAICRNIEWLPSLSGVIVLFKNGKSAFLHIPNHKLLSEQITGVWAENLRNVTCSAVNVKFRSIAYGLKIGEAVIYKTDEETGALRLQHRLKILSNEYPDADKVTGAVTYLKWSPDNFCLALCWEYIGFSLWSVQGSLLFSSLG--------NKAGIDMSLLSLDWGCEGYSLWLI-----------------EKPDKSGKPAILIFQMAKSVLVVNPTKNNHEHXXXXXXXHIIF---GPRKLLSSSETNLEYIPYPEN-----------------------------------YVTWNWPIKYAAIDLNGSRLVISGKHGFALYFFVSKKWRLFGNETQERTIEVSGGIVWYNHIVGLACFDNKEGKFEIRLYDSLQKIDNSLSTNHPVNSQILLMNIFDNTLVVLSIDGSIGLFEITLNEKS--HDISMEYIQTIPLENYIEFAACIVSFNLSSLHTEIGHN-KDVDELIRYQSLLINYSGHLLLFQRDKSFSAPRTSDKSLNSQENSFFKLAFKNTLIAKQKITFTGPLVVAYNVEIMWTPIIDEEFQSKRLKLDDWNAKIYTMENSLWLNCGSQGLRVWLPLNGGSNVTQVGEKKSKYSFLSKRIMLTFKIRNFYPLVVLNNEALLMSPMNEF----SNDFVNTPTCLNLSFSSINKNRHIFLQHIVKELLRINLGIHALDLTFELKKLPYFNHSXXXXXXXXXXXXATSKEPIPDPLLPRVVAFIQEFPNFLRTVVQCARKTELALWSYLFESAGNPKDLFESCLMNNELDTAASYLIILQNIEHPLISQKQAILLLDAALNRSNWGLVSNLIRFLKNIVEEVFKYEHARNEFKMIEKGNYKSTKETYSSFNTKKRYRSGGGIGMATSRQYSTGK--IKDIEILKSSKSAQNGNIDENCYDDLVF 3116
MY+ P+R+ P I SS+ F A+ + +QI ++ ++ + ++ Y ++ +G EW D S+IA+ T KG++L+F V E N+ Y+ + + + G+ Q + + + + I+ + +++LLV DG L + W+G ++ L++I DL+ ++A +L R +E+ +L G V+ +G+ F+ ++ ++++Q+ GVWA ++ + TC AVN K+R +A+G G ++Y D TG+++L H+L++ YPD TGAV + WSPD + WE G SLWSV G+ L +LG + + S+ WG EGY LW++ P + IL F KS L VNP +N EH+LL + P ++ S+S+ + +P + Y+ NWPI++AAID G + ++G+ GFA Y ++KW+LFGN TQE+ + V+GG+ W+N V +AC++ + + ++RLY +DN+ ++ +++ LL+N+F + +++ D SI L+ I + S+E +Q + + YI A +VS L+S+ TE G K + +S+++N +G L++ QRD+S P+ +K + I K+ + F+ P+V+A VE +WT N K + +LWL+CG G++VWLPL + + +SFLS+RIML F I N YPL VL +AL++ NE + P + ++ + I+L HI+++LL NLG AL L LPYF H +EL++H VLEEEATS+EPIPDPLLP V FI EFP FL+T+V CARKTE ALW+YLF + GNPKDLFE CLM +LDTAASYLIILQN+E P +S++ A LL + AL + W L ++IRFLK I +M ST+E SS + +R+ ++ STGK ++ + + SA+ + EN Y D++
Sbjct: 1 MYFLTGWPRRLLCPLRSEEEPFQIQP--SSQRFYF-ALVSETQISIWFSRPSVLIVSYIESVKAAAQFGIYQKAEWKPDDSMIAVATAKGYILLFDVLGGGDERNL-YEPVYPKGSPRVKVTPGYKEEQCAPALSLEMKKPVDLEAPITSLQSLQENLLVCTADGYLHVLHWDGQGSNGRKAICLSTIPLSLDLQSARAGPSLDLEGVYIRCMEYCVTLDGFAVVLSDGRLGFITPLSNTIIADQLQGVWAADVSDGTCVAVNNKYRLMAFGCASGSVLVYMIDTTTGSMQLSHKLELTPKHYPDIYNKTGAVKVICWSPDCSVAMVTWECGGLSLWSVFGAHLICTLGEDFAHRSDGTKKEPLRISSMSWGAEGYHLWVLPSNQARRRKEEHSMEEDSPPHPFLRAGILQFHFIKSALTVNPCTSNQEHVLLHGEDRLYLTCGDPTQIHSTSDAHPRAHLHPHDGSPLHQPAHPDSSLSQGLSTLLGHKHWHVVQIHSTYLESNWPIRFAAIDTAGQCMAVAGRRGFAHYSLFTRKWKLFGNITQEQNMTVTGGLAWWNDFVVVACYNFTDQQEQLRLYQRSSNLDNAFASVTKLHADTLLLNVFRDMIILFRADCSICLYSIEKRNEGINQSASVELLQEVSMSRYIPHPALVVSVTLTSVRTETGITLKAPQQACTAESIMLNLAGQLIMLQRDRS--GPQVREK--------------ETPAINKKLLPFSPPVVLAQCVENVWTTCRS-------------NKKKRHLLEALWLSCGEAGMKVWLPLFPR-------DHRKPHSFLSRRIMLPFHI-NIYPLAVLFEDALVLGATNETVLYDGLQGSSEPLEALFPYCTVERTSQIYLHHILRQLLVRNLGEQALMLAQSCASLPYFPHVMELMVHVVLEEEATSREPIPDPLLPTVAKFITEFPLFLQTIVHCARKTEYALWNYLFAAVGNPKDLFEECLMAQDLDTAASYLIILQNMEVPAVSRQHATLLFNTALEKGKWDLCRHMIRFLKAI-----------GSGEMDTPPPTPSTQEP-SSTGAFEFFRNRSISLSQSADSISTGKFNLQKTFSMPTGSSAKGADCAENMYIDMML 1063
BLAST of RIC1 domain-containing protein vs. Ensembl Medaka
Match: RIC1 (RIC1 homolog, RAB6A GEF complex partner 1 [Source:NCBI gene;Acc:101155531]) HSP 1 Score: 476.093 bits (1224), Expect = 1.042e-142 Identity = 331/1078 (30.71%), Postives = 535/1078 (49.63%), Query Frame = 3
Query: 21 MYYFFNCPKRI----SRHFVPSNITGIISSKSFALCAIFNSSQIIVFENKNNSIVAYYCRCEESLDIYGNSINLEWNSDGSLIAIGTDKGFLLIFSVKTVSQEVNVGYQNEKEFLEEGFINRQLSLFGEIILLDVISFPYKISCICLYRDDLLVAIEDGTLSRIKWNGSLLYNQE-FNLTSISFFSDLEFSKASNLSKNEAI-CRNIEWLPSLSGVIVLFKNGKSAFLHIPNHKLLSEQITGVWAENLRNVTCSAVNVKFRSIAYGLKIGEAVIYKTDEETGALRLQHRLKILSNEYPDADKVTGAVTYLKWSPDNFCLALCWEYIGFSLWSVQGSLLFSSLG--------NKAGIDMSLLSLDWGCEGYSLWLIE-----------------KPDKSGKPAILIFQMAKSVLVVNPTKNNHEHXXXXXXXHIIF---GPRKLLSSSETNLEYIPYPENYVTWNWPIKYAAIDLNGSRLVISGKHGFALYF---FVSKKWRLFGNETQERTIEVSGGIVWYNHIVGLACFDNKEGKFEIRLYDSLQKIDNSLSTNHPVNSQILLMNIFDNTLVVLSIDGSIGLFEITLNEKS--HDISMEYIQTIPLENYIEFAACIVSFNLSSLHTEIGHN-KDVDELIRYQSLLINYSGHLLLFQRDKSFSAPRTSDKSLNSQENSFFKLAFKNTLIAKQKITFTGPLVVAYNVEIMWTPIIDEEFQSKRLKLDDWNAKIYTMENSLWLNCGSQGLRVWLPLNGGSNVTQVGEKKSKYSFLSKRIMLTFKIRNFYPLVVLNNEALLMSPMNEF----SNDFVNTPTCLNLSFSSINKNRHIFLQHIVKELLRINLGIHALDLTFELKKLPYFNHSXXXXXXXXXXXXATSKEPIPDPLLPRVVAFIQEFPNFLRTVVQCARKTELALWSYLFESAGNPKDLFESCLMNNELDTAASYLIILQNIEHPLISQKQAILLLDAALNRSNWGLVSNLIRFLKNIVEEVFKYEHARNEFKMIEKGNYKSTKETYSSFNTKKRYRSGGGIGMATSRQYSTGK--IKDIEILKSSKSAQNGNIDENCYDDLVF 3116
MY+ P+R+ P I SS+ F A+ + +QI ++ ++ + ++ Y ++ +G EW D S+IA+ I E V + + + G+ Q + + + + I+ + +++LLV DG L + W+G ++ L++I DL+ ++A E + R +E+ +L G V+ +G+ F+ ++ ++++Q+ GVWA ++ + TC AVN K+R +A+G G ++Y D TG+++L H+L++ YPD TGAV + WSPD + WE G SLWSV G+ L +LG + + S+ WG EGY LW++ P + IL F KS L VNP +N EH+LL + P ++ S+S+ + +P + + P + G ++ KH + ++ W + +E+ + V+GG+ W+N V +AC++ + + ++RLY +DN+ ++ +++ LL+N+F + +++ D SI L+ I + S+E +Q + + YI A +VS L+S+ TE G K + +S+++N +G L++ QRD+S P+ +K + I K+ + F+ P+V+A VE +WT N K + +LWL+CG G++VWLPL + + +SFLS+RIML F I N YPL VL +AL++ NE + P + ++ + I+L HI+++LL NLG AL L LPYF H +EL++H VLEEEATS+EPIPDPLLP V FI EFP FL+T+V CARKTE ALW+YLF + GNPKDLFE CLM +LDTAASYLIILQN+E P +S++ A LL + AL + W L ++IRFLK I +M ST+E SS + +R+ ++ STGK ++ + + SA+ + EN Y D++
Sbjct: 1 MYFLTGWPRRLLCPLRSEEEPFQIQP--SSQRFYF-ALVSETQISIWFSRPSVLIVSYIESVKAAAQFGIYQKAEWKPDDSMIAVAVSVYIFEITRGDKCEYECGVCRGSPRVKVTPGYKEEQCAPALSLEMKKPVDLEAPITSLQSLQENLLVCTADGYLHVLHWDGQGSNGRKAICLSTIPLSLDLQSARAGPSLDLEGVYIRCMEYCVTLDGFAVVLSDGRLGFITPLSNTIIADQLQGVWAADVSDGTCVAVNNKYRLMAFGCASGSVLVYMIDTTTGSMQLSHKLELTPKHYPDIYNKTGAVKVICWSPDCSVAMVTWECGGLSLWSVFGAHLICTLGEDFAHRSDGTKKEPLRISSMSWGAEGYHLWVLPSNQARRRKEEHSMEEDSPPHPFLRAGILQFHFIKSALTVNPCTSNQEHVLLHGEDRLYLTCGDPTQIHSTSDAHPRAHLHPHDGSPLHQPAHPDSSLSQGLSTLLGHKHWHVVQIHSTYLESNWPI-----REQNMTVTGGLAWWNDFVVVACYNFTDQQEQLRLYQRSSNLDNAFASVTKLHADTLLLNVFRDMIILFRADCSICLYSIEKRNEGINQSASVELLQEVSMSRYIPHPALVVSVTLTSVRTETGITLKAPQQACTAESIMLNLAGQLIMLQRDRS--GPQVREK--------------ETPAINKKLLPFSPPVVLAQCVENVWTTCRS-------------NKKKRHLLEALWLSCGEAGMKVWLPLFPR-------DHRKPHSFLSRRIMLPFHI-NIYPLAVLFEDALVLGATNETVLYDGLQGSSEPLEALFPYCTVERTSQIYLHHILRQLLVRNLGEQALMLAQSCASLPYFPHVMELMVHVVLEEEATSREPIPDPLLPTVAKFITEFPLFLQTIVHCARKTEYALWNYLFAAVGNPKDLFEECLMAQDLDTAASYLIILQNMEVPAVSRQHATLLFNTALEKGKWDLCRHMIRFLKAI-----------GSGEMDTPPPTPSTQEP-SSTGAFEFFRNRSISLSQSADSISTGKFNLQKTFSMPTGSSAKGADCAENMYIDMML 1021
BLAST of RIC1 domain-containing protein vs. Planmine SMEST
Match: SMESG000044023.1 (SMESG000044023.1) HSP 1 Score: 2805.01 bits (7270), Expect = 0.000e+0 Identity = 1412/1427 (98.95%), Postives = 1414/1427 (99.09%), Query Frame = 3
Query: 21 MYYFFNCPKRISRHFVPSNITGIISSKSFALCAIFNSSQIIVFENKNNSIVAYYCRCEESLDIYGNSINLEWNSDGSLIAIGTDKGFLLIFSVKTVSQEVNVGYQNEKEFLEEGFINRQLSLFGEIILLDVISFPYKISCICLYRDDLLVAIEDGTLSRIKWNGSLLYNQEFNLTSISFFSDLEFSKASNLSKNEAICRNIEWLPSLSGVIVLFKNGKSAFLHIPNHKLLSEQITGVWAENLRNVTCSAVNVKFRSIAYGLKIGEAVIYKTDEETGALRLQHRLKILSNEYPDADKVTGAVTYLKWSPDNFCLALCWEYIGFSLWSVQGSLLFSSLGNKAGIDMSLLSLDWGCEGYSLWLIEKPDKSGKPAILIFQMAKSVLVVNPTKNNHEHXXXXXXXHIIFGPRKLLSSSETNLEYIPYPENYVTWNWPIKYAAIDLNGSRLVISGKHGFALYFFVSKKWRLFGNETQERTIEVSGGIVWYNHIVGLACFDNKEGKFEIRLYDSLQKIDNSLSTNHPVNSQILLMNIFDNTLVVLSIDGSIGLFEITLNEKSHDISMEYIQTIPLENYIEFAACIVSFNLSSLHTEIGHNKDVDELIRYQSLLINYSGHLLLFQRDKSFSAPRTSDKSLNSQENSFFKLAFKNTLIAKQKITFTGPLVVAYNVEIMWTPIIDEEFQSKRLKLDDWNAKIYTMENSLWLNCGSQGLRVWLPLNGGSNVTQVGEKKSKYSFLSKRIMLTFKIRNFYPLVVLNNEALLMSPMNEFSNDFVNTPTCLNLSFSSINKNRHIFLQHIVKELLRINLGIHALDLTFELKKLPYFNHSXXXXXXXXXXXXATSKEPIPDPLLPRVVAFIQEFPNFLRTVVQCARKTELALWSYLFESAGNPKDLFESCLMNNELDTAASYLIILQNIEHPLISQKQAILLLDAALNRSNWGLVSNLIRFLKNIVEEVFKYEHARNEFKMIEKGNYKSTKETYSSFNTKKRYRSGGGIGMATSRQYSTGKIKDIEILKSSKSAQNGNIDENCYDDLVFDSVGSKINTLLSPNLNVDDNNDGLSFMCNQMHLIEENPDLNLSRKQIELSDLLFECSKNSVFEKEVDIILTQFALKNFQEYHLHNVMEFFVNIQLTEFQFVSWMIRERSCSKIQDPIQAFVNLHIDFKWPLTRESEDFNKMQSYTEFASKGDFFEVLCKIRNNKVMGLNRKKLRYLATMLIKADYYEWSFLVLLMLDDYEEILSIFKCFLMNVDKISKLFEIKDFINTIMNWNFDEKTTYMAXXXXXXXXXXXXYEEKISEMQIPKVDIISERSLSEVSPKTKEDLLILSPVSKHSSIALGQLIIDPVNIKENDLNHYFKQSESVDCKLDQISGNKQIKKVYFSKTKLTANDCKISENLRSAYGFSNSIQTVKTLDPLISSELEEKSFASSCFIS 4301
MYYFFNCPKRISRHFV SNITGIISSKSFALCAIFNSSQIIVFENKNNSIVAYYCRCEESLDIYGNSINLEWNSDGSLIAIGTDKGFLLIFSVKTVSQEVNVGYQNEKEFLEEGFINRQLSLFGEIILLD + LYRDDLLVAIEDGTLSRIKWNGSLLYNQEFNLTSISFFSDLEFSKASNLSKNEAICRNIEWLPSLSGVIVLFKNGKSAFLHIPNHKLLSEQITGVWAENLRNVTCSAVNVKFRSIAYGLKIGEAVIYKTDEETGALRLQHRLKILSNEYPDADKVTGAVTYLKWSPDNFCLALCWEYIGFSLWSVQGSLLFSSLGNKAGIDMSLLSLDWGCEGYSLWLIEKPDKSGKPAILIFQMAKSVLVVNPTKNNHEHLLLLSSSHIIFGPRKLLSSSETNLEYIPYPENYVTWNWPIKYAAIDLNGSRLVISGKHGFALYFFVSKKWRLFGNETQERTIEVSGGIVWYNHIVGLACFDNKEGKFEIRLYDSLQKIDNSLSTNHPVNSQILLMNIFDNTLVVLSIDGSIGLFEITLNEKSHDISMEYIQTIPLENYIEFAACIVSFNLSSLHTEIGHNKDVDELIRYQSLLINYSGHLLLFQRDKSFSAPRTSDKSLNSQENSFFKLAFKNTLIAKQKITFTGPLVVAYNVEIMWTPIIDEEFQSK LKLDDWNAKIYTMENSLWLNCGSQGLRVWLPLNGGSNVTQVGEKKSKYSFLSKRIMLTFKIRNFYPLVVLNNEALLMSPMNEFSNDFVNTPTCLNLSFSSINKNRHIFLQHIVKELLRINLGIHALDLTFELKKLPYFNHSLELLLHEVLEEEATSKEPIPDPLLPRVVAFIQEFPNFLRTVVQCARKTELALWSYLFESAGNPKDLFESCLMNNELDTAASYLIILQNIEHPLISQKQAILLLDAALNRSNWGLVSNLIRFLKNIVEEVFKYEHARNEFKMIEKGNYKSTKETYSSFNTKKRYRSGGGIGMATSRQYSTGKIKDIEILKSSKSAQNGNIDENCYDDLVFDSVGSKINTLLSPNLNVDDNNDGLSFMCNQMHLIEENPDLNLSRKQIELSDLLFECSKNSVFEKEVDIILTQFALKNFQEYHLHNVMEFFVNIQLTEFQFVSWMIRERSCSKIQDPIQAFVNLHIDFKWPLTRESEDFNKMQSYTEFASKGDFFEVLCKIRNNKVMGLNRKKLRYLATMLIKADYYEWSFLVLLMLDDYEEILSIFKCFLMNVDKISKLFEIKDFINTIMNWNFDEKTTYMAILSKIKSSIILLYEEKISEMQIPKVDIISERSLSEVSPKTKEDLLILSPVSKHSSIALGQLIIDPVNIKENDLNHYFKQSES+DCKLDQISGNKQIKKVYFSKTKLTANDCKISENLRSAYGFSNSIQTVKTLDPLISSELEEKSFASSCFIS
Sbjct: 1 MYYFFNCPKRISRHFVQSNITGIISSKSFALCAIFNSSQIIVFENKNNSIVAYYCRCEESLDIYGNSINLEWNSDGSLIAIGTDKGFLLIFSVKTVSQEVNVGYQNEKEFLEEGFINRQLSLFGEIILLDYM----------LYRDDLLVAIEDGTLSRIKWNGSLLYNQEFNLTSISFFSDLEFSKASNLSKNEAICRNIEWLPSLSGVIVLFKNGKSAFLHIPNHKLLSEQITGVWAENLRNVTCSAVNVKFRSIAYGLKIGEAVIYKTDEETGALRLQHRLKILSNEYPDADKVTGAVTYLKWSPDNFCLALCWEYIGFSLWSVQGSLLFSSLGNKAGIDMSLLSLDWGCEGYSLWLIEKPDKSGKPAILIFQMAKSVLVVNPTKNNHEHLLLLSSSHIIFGPRKLLSSSETNLEYIPYPENYVTWNWPIKYAAIDLNGSRLVISGKHGFALYFFVSKKWRLFGNETQERTIEVSGGIVWYNHIVGLACFDNKEGKFEIRLYDSLQKIDNSLSTNHPVNSQILLMNIFDNTLVVLSIDGSIGLFEITLNEKSHDISMEYIQTIPLENYIEFAACIVSFNLSSLHTEIGHNKDVDELIRYQSLLINYSGHLLLFQRDKSFSAPRTSDKSLNSQENSFFKLAFKNTLIAKQKITFTGPLVVAYNVEIMWTPIIDEEFQSKMLKLDDWNAKIYTMENSLWLNCGSQGLRVWLPLNGGSNVTQVGEKKSKYSFLSKRIMLTFKIRNFYPLVVLNNEALLMSPMNEFSNDFVNTPTCLNLSFSSINKNRHIFLQHIVKELLRINLGIHALDLTFELKKLPYFNHSLELLLHEVLEEEATSKEPIPDPLLPRVVAFIQEFPNFLRTVVQCARKTELALWSYLFESAGNPKDLFESCLMNNELDTAASYLIILQNIEHPLISQKQAILLLDAALNRSNWGLVSNLIRFLKNIVEEVFKYEHARNEFKMIEKGNYKSTKETYSSFNTKKRYRSGGGIGMATSRQYSTGKIKDIEILKSSKSAQNGNIDENCYDDLVFDSVGSKINTLLSPNLNVDDNNDGLSFMCNQMHLIEENPDLNLSRKQIELSDLLFECSKNSVFEKEVDIILTQFALKNFQEYHLHNVMEFFVNIQLTEFQFVSWMIRERSCSKIQDPIQAFVNLHIDFKWPLTRESEDFNKMQSYTEFASKGDFFEVLCKIRNNKVMGLNRKKLRYLATMLIKADYYEWSFLVLLMLDDYEEILSIFKCFLMNVDKISKLFEIKDFINTIMNWNFDEKTTYMAILSKIKSSIILLYEEKISEMQIPKVDIISERSLSEVSPKTKEDLLILSPVSKHSSIALGQLIIDPVNIKENDLNHYFKQSESIDCKLDQISGNKQIKKVYFSKTKLTANDCKISENLRSAYGFSNSIQTVKTLDPLISSELEEKSFASSCFIS 1417
BLAST of RIC1 domain-containing protein vs. Planmine SMEST
Match: SMESG000044023.1 (SMESG000044023.1) HSP 1 Score: 2777.27 bits (7198), Expect = 0.000e+0 Identity = 1403/1427 (98.32%), Postives = 1405/1427 (98.46%), Query Frame = 3
Query: 21 MYYFFNCPKRISRHFVPSNITGIISSKSFALCAIFNSSQIIVFENKNNSIVAYYCRCEESLDIYGNSINLEWNSDGSLIAIGTDKGFLLIFSVKTVSQEVNVGYQNEKEFLEEGFINRQLSLFGEIILLDVISFPYKISCICLYRDDLLVAIEDGTLSRIKWNGSLLYNQEFNLTSISFFSDLEFSKASNLSKNEAICRNIEWLPSLSGVIVLFKNGKSAFLHIPNHKLLSEQITGVWAENLRNVTCSAVNVKFRSIAYGLKIGEAVIYKTDEETGALRLQHRLKILSNEYPDADKVTGAVTYLKWSPDNFCLALCWEYIGFSLWSVQGSLLFSSLGNKAGIDMSLLSLDWGCEGYSLWLIEKPDKSGKPAILIFQMAKSVLVVNPTKNNHEHXXXXXXXHIIFGPRKLLSSSETNLEYIPYPENYVTWNWPIKYAAIDLNGSRLVISGKHGFALYFFVSKKWRLFGNETQERTIEVSGGIVWYNHIVGLACFDNKEGKFEIRLYDSLQKIDNSLSTNHPVNSQILLMNIFDNTLVVLSIDGSIGLFEITLNEKSHDISMEYIQTIPLENYIEFAACIVSFNLSSLHTEIGHNKDVDELIRYQSLLINYSGHLLLFQRDKSFSAPRTSDKSLNSQENSFFKLAFKNTLIAKQKITFTGPLVVAYNVEIMWTPIIDEEFQSKRLKLDDWNAKIYTMENSLWLNCGSQGLRVWLPLNGGSNVTQVGEKKSKYSFLSKRIMLTFKIRNFYPLVVLNNEALLMSPMNEFSNDFVNTPTCLNLSFSSINKNRHIFLQHIVKELLRINLGIHALDLTFELKKLPYFNHSXXXXXXXXXXXXATSKEPIPDPLLPRVVAFIQEFPNFLRTVVQCARKTELALWSYLFESAGNPKDLFESCLMNNELDTAASYLIILQNIEHPLISQKQAILLLDAALNRSNWGLVSNLIRFLKNIVEEVFKYEHARNEFKMIEKGNYKSTKETYSSFNTKKRYRSGGGIGMATSRQYSTGKIKDIEILKSSKSAQNGNIDENCYDDLVFDSVGSKINTLLSPNLNVDDNNDGLSFMCNQMHLIEENPDLNLSRKQIELSDLLFECSKNSVFEKEVDIILTQFALKNFQEYHLHNVMEFFVNIQLTEFQFVSWMIRERSCSKIQDPIQAFVNLHIDFKWPLTRESEDFNKMQSYTEFASKGDFFEVLCKIRNNKVMGLNRKKLRYLATMLIKADYYEWSFLVLLMLDDYEEILSIFKCFLMNVDKISKLFEIKDFINTIMNWNFDEKTTYMAXXXXXXXXXXXXYEEKISEMQIPKVDIISERSLSEVSPKTKEDLLILSPVSKHSSIALGQLIIDPVNIKENDLNHYFKQSESVDCKLDQISGNKQIKKVYFSKTKLTANDCKISENLRSAYGFSNSIQTVKTLDPLISSELEEKSFASSCFIS 4301
MYYFFNCPKRISRHFV SNITGIISSKSFALCAIFNSSQIIVFENKNNSIVAYYCRCEESLDIYGNSINLEWNSDGSLIAIGTDKGFLLIFSVKTVSQEVNVGYQNEKEFLEEGFINRQLSLFGEIILLD + LYRDDLLVAIEDGTLSRIKWNGSLLYNQEFNLTSISFFSDLEFSKASNLSKNEAICRNIEWLPSLSGVIVLFKNGKSAFLHIPNHKLLSEQITGVWAENLRNVTCSAVNVKFRSIAYGLKIGEAVIYKTDEETGALRLQHRLKILSNEYPDADKVTGAVTYLKWSPDNFCLALCWEYIGFSLWSVQGSLLFSSLGNKAGIDMSLLSLDWGCEGYSLWLIEKPDKSGKPAILIFQMAKSVLVVNPTKNNHEHLLLLSSSHIIFGPRKLLSSSETNLEYIPYPENYVTWNWPIKYAAIDLNGSRLVISGKHGFALYFFVSKKWRLFGNETQERTIEVSGGIVWYNHIVGLACFDNKEGKFEIRLYDSLQKIDNSLSTNHPVNSQILLMNIFDNTLVVLSIDGSIGLFEITLNEKSHDISMEYIQTIPLENYIEFAACIVSFNLSSLHTEIGHNKDVDELIRYQSLLINYSGHLLLFQRDKSFSAPRTSDKSLNSQENSFFKLAFKNTLIAKQKITFTGPLVVAYNVEIMWTPIIDEEFQSK LKLDDWNAKIYTMENSLWLNCGSQGLRVWLPLNGGSNVTQVGEKKSKYSFLSKRIMLTFKIRNFYPLVVLNNEALLMSPMNEFSNDFVNTPTCLNLSFSSINKNRHIFLQHIVKELLRINLGIHALDLTFELKKLPYFNHSLELLLHEVLEEEATSKEPIPDPLLPRVVAFIQEFPNFLRTVVQCARKTELALWSYLFESAGNPKDLFESCLMNNELDTAASYLIILQNIEHPLISQKQAILLLDAALNRSNWGLVSNLIRFLKNI ARNEFKMIEKGNYKSTKETYSSFNTKKRYRSGGGIGMATSRQYSTGKIKDIEILKSSKSAQNGNIDENCYDDLVFDSVGSKINTLLSPNLNVDDNNDGLSFMCNQMHLIEENPDLNLSRKQIELSDLLFECSKNSVFEKEVDIILTQFALKNFQEYHLHNVMEFFVNIQLTEFQFVSWMIRERSCSKIQDPIQAFVNLHIDFKWPLTRESEDFNKMQSYTEFASKGDFFEVLCKIRNNKVMGLNRKKLRYLATMLIKADYYEWSFLVLLMLDDYEEILSIFKCFLMNVDKISKLFEIKDFINTIMNWNFDEKTTYMAILSKIKSSIILLYEEKISEMQIPKVDIISERSLSEVSPKTKEDLLILSPVSKHSSIALGQLIIDPVNIKENDLNHYFKQSES+DCKLDQISGNKQIKKVYFSKTKLTANDCKISENLRSAYGFSNSIQTVKTLDPLISSELEEKSFASSCFIS
Sbjct: 1 MYYFFNCPKRISRHFVQSNITGIISSKSFALCAIFNSSQIIVFENKNNSIVAYYCRCEESLDIYGNSINLEWNSDGSLIAIGTDKGFLLIFSVKTVSQEVNVGYQNEKEFLEEGFINRQLSLFGEIILLDYM----------LYRDDLLVAIEDGTLSRIKWNGSLLYNQEFNLTSISFFSDLEFSKASNLSKNEAICRNIEWLPSLSGVIVLFKNGKSAFLHIPNHKLLSEQITGVWAENLRNVTCSAVNVKFRSIAYGLKIGEAVIYKTDEETGALRLQHRLKILSNEYPDADKVTGAVTYLKWSPDNFCLALCWEYIGFSLWSVQGSLLFSSLGNKAGIDMSLLSLDWGCEGYSLWLIEKPDKSGKPAILIFQMAKSVLVVNPTKNNHEHLLLLSSSHIIFGPRKLLSSSETNLEYIPYPENYVTWNWPIKYAAIDLNGSRLVISGKHGFALYFFVSKKWRLFGNETQERTIEVSGGIVWYNHIVGLACFDNKEGKFEIRLYDSLQKIDNSLSTNHPVNSQILLMNIFDNTLVVLSIDGSIGLFEITLNEKSHDISMEYIQTIPLENYIEFAACIVSFNLSSLHTEIGHNKDVDELIRYQSLLINYSGHLLLFQRDKSFSAPRTSDKSLNSQENSFFKLAFKNTLIAKQKITFTGPLVVAYNVEIMWTPIIDEEFQSKMLKLDDWNAKIYTMENSLWLNCGSQGLRVWLPLNGGSNVTQVGEKKSKYSFLSKRIMLTFKIRNFYPLVVLNNEALLMSPMNEFSNDFVNTPTCLNLSFSSINKNRHIFLQHIVKELLRINLGIHALDLTFELKKLPYFNHSLELLLHEVLEEEATSKEPIPDPLLPRVVAFIQEFPNFLRTVVQCARKTELALWSYLFESAGNPKDLFESCLMNNELDTAASYLIILQNIEHPLISQKQAILLLDAALNRSNWGLVSNLIRFLKNI---------ARNEFKMIEKGNYKSTKETYSSFNTKKRYRSGGGIGMATSRQYSTGKIKDIEILKSSKSAQNGNIDENCYDDLVFDSVGSKINTLLSPNLNVDDNNDGLSFMCNQMHLIEENPDLNLSRKQIELSDLLFECSKNSVFEKEVDIILTQFALKNFQEYHLHNVMEFFVNIQLTEFQFVSWMIRERSCSKIQDPIQAFVNLHIDFKWPLTRESEDFNKMQSYTEFASKGDFFEVLCKIRNNKVMGLNRKKLRYLATMLIKADYYEWSFLVLLMLDDYEEILSIFKCFLMNVDKISKLFEIKDFINTIMNWNFDEKTTYMAILSKIKSSIILLYEEKISEMQIPKVDIISERSLSEVSPKTKEDLLILSPVSKHSSIALGQLIIDPVNIKENDLNHYFKQSESIDCKLDQISGNKQIKKVYFSKTKLTANDCKISENLRSAYGFSNSIQTVKTLDPLISSELEEKSFASSCFIS 1408 The following BLAST results are available for this feature:
BLAST of RIC1 domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of RIC1 domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 2
BLAST of RIC1 domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 2
BLAST of RIC1 domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 1
BLAST of RIC1 domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of RIC1 domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 3
BLAST of RIC1 domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of RIC1 domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of RIC1 domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 2
BLAST of RIC1 domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 0
BLAST of RIC1 domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of RIC1 domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 1
BLAST of RIC1 domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 2
BLAST of RIC1 domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 2
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30019230 ID=SMED30019230|Name=RIC1 domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=4721bpback to top protein sequence of SMED30019230-orf-1 >SMED30019230-orf-1 ID=SMED30019230-orf-1|Name=SMED30019230-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1428bp MYYFFNCPKRISRHFVPSNITGIISSKSFALCAIFNSSQIIVFENKNNSIback to top Annotated Terms
The following terms have been associated with this transcript:
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