Serine protease

Overview
NameSerine protease
Smed IDSMED30019227
Length (bp)1208
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Serine protease (SMED30019227) t-SNE clustered cells

Violin plots show distribution of expression levels for Serine protease (SMED30019227) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Serine protease (SMED30019227) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Serine protease (SMED30019227) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30019227

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 6

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
prepharyngeal regionSMED30019227SMESG000044335.1 SmedASXL_004373SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
parapharyngeal regionSMED30019227SMESG000044335.1 SmedASXL_004373SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
prepharyngeal regionSMED30019227SMESG000044335.1 SmedASXL_005830SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
parapharyngeal regionSMED30019227SMESG000044335.1 SmedASXL_005830SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
parapharyngeal regionSMED30019227SMESG000044335.1 dd_Smed_v6_1427_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
head regionSMED30019227SMESG000044335.1 OX_Smed_1.0.07551ox_Smed_v2PMID:24238224
Kao et al., 2013		whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Serine protease vs. Ensembl Human
Match: HPN (hepsin [Source:HGNC Symbol;Acc:HGNC:5155])

HSP 1 Score: 178.718 bits (452), Expect = 2.664e-51
Identity = 96/254 (37.80%), Postives = 144/254 (56.69%), Query Frame = 3 
Query:  303 CGISNGSKYKVFGGWRSMPGEWPWQVQIEREGAHHCGGALIHPNWVVTAAHCTFFFQDLPIEKWRIRAGKTQTNMTEPHEQNVRVKKLIDHPGFTLFT------KYHDIALIQLEDPMYFDYKFVSPICLPNPQESF-DDHVCTLSGYGKTESSGEGASTYLLEVNLPIISADTCQEKHCNSNSIYEENLCAGFKEGKRDACTGDSGGPIVCEKLSVNGFKQFVLAGVVSYGSGCGGKDTPGVYTRISSYLDWI 1043
            CG       ++ GG  +  G WPWQV +  +GAH CGG+L+  +WV+TAAHC F  ++  + +WR+ AG        PH   + V+ ++ H G+  F         +DIAL+ L  P+    +++ P+CLP   ++  D  +CT++G+G T+  G+ A   L E  +PIIS D C       N I  +  CAG+ EG  DAC GDSGGP VCE  S++   ++ L G+VS+G+GC     PGVYT++S + +WI
Sbjct:  153 CGRRKLPVDRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHC-FPERNRVLSRWRVFAGAVA--QASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLT-EYIQPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGV-LQEARVPIISNDVCNGADFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCED-SISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDFREWI 400
[Close]
BLAST of Serine protease vs. Ensembl Human
Match: HPN (hepsin [Source:HGNC Symbol;Acc:HGNC:5155])

HSP 1 Score: 178.718 bits (452), Expect = 2.664e-51
Identity = 96/254 (37.80%), Postives = 144/254 (56.69%), Query Frame = 3 
Query:  303 CGISNGSKYKVFGGWRSMPGEWPWQVQIEREGAHHCGGALIHPNWVVTAAHCTFFFQDLPIEKWRIRAGKTQTNMTEPHEQNVRVKKLIDHPGFTLFT------KYHDIALIQLEDPMYFDYKFVSPICLPNPQESF-DDHVCTLSGYGKTESSGEGASTYLLEVNLPIISADTCQEKHCNSNSIYEENLCAGFKEGKRDACTGDSGGPIVCEKLSVNGFKQFVLAGVVSYGSGCGGKDTPGVYTRISSYLDWI 1043
            CG       ++ GG  +  G WPWQV +  +GAH CGG+L+  +WV+TAAHC F  ++  + +WR+ AG        PH   + V+ ++ H G+  F         +DIAL+ L  P+    +++ P+CLP   ++  D  +CT++G+G T+  G+ A   L E  +PIIS D C       N I  +  CAG+ EG  DAC GDSGGP VCE  S++   ++ L G+VS+G+GC     PGVYT++S + +WI
Sbjct:  153 CGRRKLPVDRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHC-FPERNRVLSRWRVFAGAVA--QASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLT-EYIQPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGV-LQEARVPIISNDVCNGADFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCED-SISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDFREWI 400
[Close]
BLAST of Serine protease vs. Ensembl Human
Match: HPN (hepsin [Source:HGNC Symbol;Acc:HGNC:5155])

HSP 1 Score: 178.718 bits (452), Expect = 2.664e-51
Identity = 96/254 (37.80%), Postives = 144/254 (56.69%), Query Frame = 3 
Query:  303 CGISNGSKYKVFGGWRSMPGEWPWQVQIEREGAHHCGGALIHPNWVVTAAHCTFFFQDLPIEKWRIRAGKTQTNMTEPHEQNVRVKKLIDHPGFTLFT------KYHDIALIQLEDPMYFDYKFVSPICLPNPQESF-DDHVCTLSGYGKTESSGEGASTYLLEVNLPIISADTCQEKHCNSNSIYEENLCAGFKEGKRDACTGDSGGPIVCEKLSVNGFKQFVLAGVVSYGSGCGGKDTPGVYTRISSYLDWI 1043
            CG       ++ GG  +  G WPWQV +  +GAH CGG+L+  +WV+TAAHC F  ++  + +WR+ AG        PH   + V+ ++ H G+  F         +DIAL+ L  P+    +++ P+CLP   ++  D  +CT++G+G T+  G+ A   L E  +PIIS D C       N I  +  CAG+ EG  DAC GDSGGP VCE  S++   ++ L G+VS+G+GC     PGVYT++S + +WI
Sbjct:  153 CGRRKLPVDRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHC-FPERNRVLSRWRVFAGAVA--QASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLT-EYIQPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGV-LQEARVPIISNDVCNGADFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCED-SISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDFREWI 400
[Close]
BLAST of Serine protease vs. Ensembl Human
Match: HPN (hepsin [Source:HGNC Symbol;Acc:HGNC:5155])

HSP 1 Score: 178.718 bits (452), Expect = 2.664e-51
Identity = 96/254 (37.80%), Postives = 144/254 (56.69%), Query Frame = 3 
Query:  303 CGISNGSKYKVFGGWRSMPGEWPWQVQIEREGAHHCGGALIHPNWVVTAAHCTFFFQDLPIEKWRIRAGKTQTNMTEPHEQNVRVKKLIDHPGFTLFT------KYHDIALIQLEDPMYFDYKFVSPICLPNPQESF-DDHVCTLSGYGKTESSGEGASTYLLEVNLPIISADTCQEKHCNSNSIYEENLCAGFKEGKRDACTGDSGGPIVCEKLSVNGFKQFVLAGVVSYGSGCGGKDTPGVYTRISSYLDWI 1043
            CG       ++ GG  +  G WPWQV +  +GAH CGG+L+  +WV+TAAHC F  ++  + +WR+ AG        PH   + V+ ++ H G+  F         +DIAL+ L  P+    +++ P+CLP   ++  D  +CT++G+G T+  G+ A   L E  +PIIS D C       N I  +  CAG+ EG  DAC GDSGGP VCE  S++   ++ L G+VS+G+GC     PGVYT++S + +WI
Sbjct:  153 CGRRKLPVDRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHC-FPERNRVLSRWRVFAGAVA--QASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLT-EYIQPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGV-LQEARVPIISNDVCNGADFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCED-SISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDFREWI 400
[Close]
BLAST of Serine protease vs. Ensembl Human
Match: TMPRSS3 (transmembrane serine protease 3 [Source:HGNC Symbol;Acc:HGNC:11877])

HSP 1 Score: 176.407 bits (446), Expect = 5.695e-50
Identity = 96/261 (36.78%), Postives = 146/261 (55.94%), Query Frame = 3 
Query:  297 NKCGISNGSKYKVFGGWRSMPGEWPWQVQIEREGAHHCGGALIHPNWVVTAAHCTFFFQDLPIEK-WRIRAGKTQTNMTEPHEQNVRVKKLIDHPGFTLFTKYHDIALIQLEDPMYFDYKFVSPICLPNPQESF-DDHVCTLSGYGKTESSGEGASTYLLEVNLPIISADTCQEKHCNSNSIYEENLCAGFKEGKRDACTGDSGGPIVCEKLSVNGFKQFVLAGVVSYGSGCGGKDTPGVYTRISSYLDWIEYETGIEVST 1073
              CG   G   ++ GG  S+  +WPWQ  ++ +G H CGG++I P W++TAAHC +   DL + K W I+ G     +  P   ++ V+K++ H  +      +DIAL++L  P+ F+ + + P+CLPN +E+F D  VC  SG+G TE     AS  L    +P+IS   C  +      I    LCAG+  G  D+C GDSGGP+VC++      + + L G  S+G GC   + PGVYTR++S+LDWI  +   ++ T
Sbjct:  205 TACGHRRGYSSRIVGGNMSLLSQWPWQASLQFQGYHLCGGSVITPLWIITAAHCVY---DLYLPKSWTIQVGLVSL-LDNPAPSHL-VEKIVYHSKYKPKRLGNDIALMKLAGPLTFN-EMIQPVCLPNSEENFPDGKVCWTSGWGATEDGAGDASPVLNHAAVPLISNKICNHRDVYGGIISPSMLCAGYLTGGVDSCQGDSGGPLVCQER-----RLWKLVGATSFGIGCAEVNKPGVYTRVTSFLDWIHEQMERDLKT 454
[Close]
BLAST of Serine protease vs. Ensembl Celegans
Match: try-1 (TRYpsin-like protease [Source:UniProtKB/TrEMBL;Acc:Q23528])

HSP 1 Score: 144.436 bits (363), Expect = 5.798e-40
Identity = 85/245 (34.69%), Postives = 131/245 (53.47%), Query Frame = 3 
Query:  327 YKVFGGWRSMPGEWPWQVQI-EREGAHHCGGALIHPNWVVTAAHCTFFFQDLPIEKWRIRAGKTQTNMTEPHEQNVRVKKLIDHPGFTL-FTKYHDIALIQLEDPMYFDYKFVSPICLPNPQESFDDHVCTLSGYGKTESSGEGASTYLLEVNLPIISADTCQEKHCNSNSIYEEN-LCAGFKEGKRDACTGDSGGPIVCEKLSVNGFKQFVLAGVVSYGSGCGGKDTPGVYTRISSYLDWIEYE 1052
            +++ GG  S P  WPW VQ+  R G H CGG+LI PN+V+TAAHC  F +D     + +R G  ++    PH    RV  +  HP + + F   +D A++++  P+        PICLP+   + ++ +C ++G+G T      ++  L E+++P++S   C         I+  + LCAG+  GK D+C GDSGGP++C +        + L GVVS+G GC     PGVY  + S   WI  E
Sbjct:   56 HRLIGGSESSPHSWPWTVQLLSRLGHHRCGGSLIDPNFVLTAAHC--FAKDRRPTSYSVRVGGHRSGSGSPH----RVTAVSIHPWYNIGFPSSYDFAIMRIHPPVNTSTT-ARPICLPS-LPAVENRLCVVTGWGSTIEGSSLSAPTLREIHVPLLSTLFCSSLPNYIGRIHLPSMLCAGYSYGKIDSCQGDSGGPLMCAR-----DGHWELTGVVSWGIGCARPGMPGVYGNVHSASTWINLE 287
[Close]
BLAST of Serine protease vs. Ensembl Celegans
Match: svh-1 (HGF/MSP/plasminogen-like protein [Source:UniProtKB/TrEMBL;Acc:Q17800])

HSP 1 Score: 140.969 bits (354), Expect = 4.091e-36
Identity = 81/242 (33.47%), Postives = 130/242 (53.72%), Query Frame = 3 
Query:  330 KVFGGWRSMPGEWPWQVQIEREG--AHHCGGALIHPNWVVTAAHCTFFFQDLPIEKWRIRAGKTQTNMTEPHEQNVRVKKLIDHPGFT-LFTKYHDIALIQLEDPMYFDYKFVSPICLPNPQESFD-DHVCTLSGYGKTESSGEGASTYLLEVNLPIISADTCQEKHCNSNSIYEENLCAGFKEGKRDACTGDSGGPIVCEKLSVNGFKQFVLAGVVSYGSGCGGKDTPGVYTRISSYLDWI 1043
            +V GG+ ++PG +PW   +  +   AHHCG +++    ++TAAHC  F +D  +  + +  G    N T+ +EQ   ++++  +P +  +F+  HDIA++++  P     ++  PICLP+    +     C +SG+G   S G   +  L    +PII+   C       +S+     CAG+ EG  D+C GDSGGP  C +        FVLAGV+S+G GC  K  PG+YT ++ YL WI
Sbjct:  712 RVVGGFETVPGAFPWTAALRNKATKAHHCGASILDKTHLITAAHC--FEEDERVSSYEVVVGDWDNNQTDGNEQIFYLQRIHFYPLYKDIFS--HDIAILEIPYPGIEFNEYAQPICLPSKDFVYTPGRQCVVSGWG---SMGLRYAERLQAALIPIINRFDCVNSSQIYSSMSRSAFCAGYLEGGIDSCQGDSGGPFACRRED----GAFVLAGVISWGDGCAQKKQPGIYTMVAPYLSWI 942
[Close]
BLAST of Serine protease vs. Ensembl Celegans
Match: try-3 (TRYpsin-like protease [Source:UniProtKB/TrEMBL;Acc:Q94176])

HSP 1 Score: 75.8702 bits (185), Expect = 2.233e-15
Identity = 76/238 (31.93%), Postives = 108/238 (45.38%), Query Frame = 3 
Query:  408 CGGALIHPNWVVTAAHCTFFFQDLPIEKWRIRAGKTQTNMTEP---HEQNVRVKKLIDHPGFTLFTKYHDIALIQLEDPMYFDYKFVSPICLPNPQESFDDHV--CTLSGYGKT---ESSGEGA---STYLLEVNLPIISADTCQEK----HCNSNSIYEENLCAG-FKEGKRDACTGDSGGPIVCEKLSVNGFKQFVLAGVVSYGS-GCGG----KDTPGVYTRISSYLDWIEYETG 1058
            CG  +I   W+VTAAHC    Q            ++   + EP    E++  VK+   H G+   T  +DIAL+++   +      + P+CL +             + GYG T   +SSGE     S  L   ++PIIS D C +        S  I    +CAG +  G      GDSGGP++  K   NG  ++V  G+ SYG+ G  G       PGVYTRIS Y+ WI+   G
Sbjct:   16 CGATVIDDFWLVTAAHCALQLQT-----------RSFVYVREPKNNRERSFSVKEAYIHSGYNNQTADNDIALLRISSDL--SKLGIKPVCLVHDDSKLLKQYKNGVVIGYGLTLGEDSSGEPKLINSQTLQSTSVPIISDDDCVKTWRFLSLLSVKITGYQICAGAYLHG---TAPGDSGGPLLIHK--SNG--EYVQIGITSYGADGLDGVIDQGKFPGVYTRISKYVPWIQGVIG 233
[Close]
BLAST of Serine protease vs. Ensembl Celegans
Match: try-3 (TRYpsin-like protease [Source:UniProtKB/TrEMBL;Acc:Q94176])

HSP 1 Score: 76.2554 bits (186), Expect = 2.613e-15
Identity = 81/269 (30.11%), Postives = 120/269 (44.61%), Query Frame = 3 
Query:  327 YKVFGGWRSMPGEWPWQVQIEREGAHH----CGGALIHPNWVVTAAHCTFFFQDLPIEKWRIRAGKTQTNMTEP---HEQNVRVKKLIDHPGFTLFTKYHDIALIQLEDPMYFDYKFVSPICLPNPQESFDDHV--CTLSGYGKT---ESSGEGA---STYLLEVNLPIISADTCQEK----HCNSNSIYEENLCAG-FKEGKRDACTGDSGGPIVCEKLSVNGFKQFVLAGVVSYGS-GCGG----KDTPGVYTRISSYLDWIEYETG 1058
            +++ GG  S+     W  ++   G +     CG  +I   W+VTAAHC    Q            ++   + EP    E++  VK+   H G+   T  +DIAL+++   +      + P+CL +             + GYG T   +SSGE     S  L   ++PIIS D C +        S  I    +CAG +  G      GDSGGP++  K   NG  ++V  G+ SYG+ G  G       PGVYTRIS Y+ WI+   G
Sbjct:   36 FRIIGG-NSIDDGANWMAKLVSYGDNGQGILCGATVIDDFWLVTAAHCALQLQT-----------RSFVYVREPKNNRERSFSVKEAYIHSGYNNQTADNDIALLRISSDL--SKLGIKPVCLVHDDSKLLKQYKNGVVIGYGLTLGEDSSGEPKLINSQTLQSTSVPIISDDDCVKTWRFLSLLSVKITGYQICAGAYLHG---TAPGDSGGPLLIHK--SNG--EYVQIGITSYGADGLDGVIDQGKFPGVYTRISKYVPWIQGVIG 283
[Close]
BLAST of Serine protease vs. Ensembl Fly
Match: Sb (gene:FBgn0003319 transcript:FBtr0344008)

HSP 1 Score: 161.384 bits (407), Expect = 4.030e-43
Identity = 97/264 (36.74%), Postives = 146/264 (55.30%), Query Frame = 3 
Query:  294 NNKCGISNGSK--YKVFGGWRSMPGEWPWQVQIER------EGAHHCGGALIHPNWVVTAAHCTFFFQDLPIEKWRIRAGK---TQTNMTEPHEQNVRVKKLIDHPGFTLFTKYHDIALIQLEDPMYFDYKFVSPICLPNPQESFDDHVCTLSGYGKTESSGEGASTYLLEVNLPIISADTCQEKHCNSNS---IYEENLCAGFKEGKRDACTGDSGGPIVCEKLSVNGFKQFVLAGVVSYGSGCGGKDTPGVYTRISSYLDWI 1043
             ++CG+   ++   ++ GG  +  G WPWQV + R         H CGGALI+ NW+ TA HC     DL I + RIR G+   +      P+ +    KK++ HP ++  T  +D+AL++LE P+ F    VSPICLP           T++G+G+  S G    + L EV++PI+S D C+     +     I +  LCAG++ G +D+C GDSGGP+  +  S +G  +F LAG++S+G GC   + PGV TRIS +  WI
Sbjct:  529 RSECGVPTLARPETRIVGGKSAAFGRWPWQVSVRRTSFFGFSSTHRCGGALINENWIATAGHC---VDDLLISQIRIRVGEYDFSHVQEQLPYIERGVAKKVV-HPKYSFLTYEYDLALVKLEQPLEFA-PHVSPICLPETDSLLIGMNATVTGWGRL-SEGGTLPSVLQEVSVPIVSNDNCKSMFMRAGRQEFIPDIFLCAGYETGGQDSCQGDSGGPL--QAKSQDG--RFFLAGIISWGIGCAEANLPGVCTRISKFTPWI 782
[Close]
BLAST of Serine protease vs. Ensembl Fly
Match: Sb (gene:FBgn0003319 transcript:FBtr0083250)

HSP 1 Score: 161.384 bits (407), Expect = 4.030e-43
Identity = 97/264 (36.74%), Postives = 146/264 (55.30%), Query Frame = 3 
Query:  294 NNKCGISNGSK--YKVFGGWRSMPGEWPWQVQIER------EGAHHCGGALIHPNWVVTAAHCTFFFQDLPIEKWRIRAGK---TQTNMTEPHEQNVRVKKLIDHPGFTLFTKYHDIALIQLEDPMYFDYKFVSPICLPNPQESFDDHVCTLSGYGKTESSGEGASTYLLEVNLPIISADTCQEKHCNSNS---IYEENLCAGFKEGKRDACTGDSGGPIVCEKLSVNGFKQFVLAGVVSYGSGCGGKDTPGVYTRISSYLDWI 1043
             ++CG+   ++   ++ GG  +  G WPWQV + R         H CGGALI+ NW+ TA HC     DL I + RIR G+   +      P+ +    KK++ HP ++  T  +D+AL++LE P+ F    VSPICLP           T++G+G+  S G    + L EV++PI+S D C+     +     I +  LCAG++ G +D+C GDSGGP+  +  S +G  +F LAG++S+G GC   + PGV TRIS +  WI
Sbjct:  529 RSECGVPTLARPETRIVGGKSAAFGRWPWQVSVRRTSFFGFSSTHRCGGALINENWIATAGHC---VDDLLISQIRIRVGEYDFSHVQEQLPYIERGVAKKVV-HPKYSFLTYEYDLALVKLEQPLEFA-PHVSPICLPETDSLLIGMNATVTGWGRL-SEGGTLPSVLQEVSVPIVSNDNCKSMFMRAGRQEFIPDIFLCAGYETGGQDSCQGDSGGPL--QAKSQDG--RFFLAGIISWGIGCAEANLPGVCTRISKFTPWI 782
[Close]
BLAST of Serine protease vs. Ensembl Fly
Match: CG3355 (gene:FBgn0031619 transcript:FBtr0077376)

HSP 1 Score: 152.14 bits (383), Expect = 1.240e-42
Identity = 93/271 (34.32%), Postives = 147/271 (54.24%), Query Frame = 3 
Query:  261 PLNKNEKPQKRNNKCGISNGSKYKVFGGWRSMPGEWPWQVQIEREGAHH----CGGALIHPNWVVTAAHCTFFFQDLPIEKWRIRAGKTQTNMTEPHEQNVRVKKLIDHPGFTLFTKYHDIALIQLEDPMYFDYKFVSPICLPNPQESFDDHVCTLSGYGKTESSGEGASTYLLEVNLPIISADTCQEKHCNSNSIYEENLCAGF-KEGKRDACTGDSGGPIVCEKLSVNGFKQFVLAGVVSYGSGCGGKDTPGVYTRISSYLDWIEYETG 1058
            P ++N+   K+N  CG  N ++  + GG +    ++PW  Q+ + G H+    CGG+LI+  +V+TAAHC    +D    +  IR  +   +  +P      V+  + HP +      +D+AL++LE P+        P+CLP    +FD     ++G+G  +  G   S YL EVN+P+I+   C++     + I E  LCAG  ++G +DAC GDSGGP++  +       ++ LAGVVS+G GC  K+ PGVY R+S +LDWI   T 
Sbjct:   54 PKSRNQCTAKQNCFCGTPNVNR--IVGGQQVRSNKYPWTAQLVK-GRHYPRLFCGGSLINDRYVLTAAHCVHGNRD----QITIRLLQIDRSSRDPGIVRKVVQTTV-HPNYDPNRIVNDVALLKLESPVPLTGNM-RPVCLPEANHNFDGKTAVVAGWGLIKEGGV-TSNYLQEVNVPVITNAQCRQTR-YKDKIAEVMLCAGLVQQGGKDACQGDSGGPLIVNE------GRYKLAGVVSFGYGCAQKNAPGVYARVSKFLDWIRKNTA 307
[Close]
BLAST of Serine protease vs. Ensembl Fly
Match: tpr (gene:FBgn0034661 transcript:FBtr0071743)

HSP 1 Score: 153.68 bits (387), Expect = 1.490e-42
Identity = 82/251 (32.67%), Postives = 143/251 (56.97%), Query Frame = 3 
Query:  303 CGISNGSKYKVFGGWRSMPGEWPWQVQIEREGAHHCGGALIHPNWVVTAAHCTFFFQDLPIEKWRIRAGKTQTNMTEPHEQNVRVKKLIDHPGFTLFTKYHDIALIQLEDPMYFDYKFVSPICLPNPQESFDDHVCTLSGYGKTESSGEGASTYLLEVNLPIISADTCQEKHCNSNSIYEENLCAGFKEGKRDACTGDSGGPIVCEKLSVNGFKQFVLAGVVSYGSGCGGKDTPGVYTRISSYLDWIEYET 1055
            CGI+N  K ++ GG  +   ++PW   +   G  +C  +L++  +++TA+HC + F+    E+  +R  +    M+   + + +V ++I HP +      +DIA+I+L++P+ F+ + + P+C+P P  SF      ++G+G  +  G  + T L EV +PI+S D C++     N I +  LC G+ EG +D+C GDSGGP+    +  +G ++  +AGVVS+G GC     PGVY R++ Y  WI+  T
Sbjct:  118 CGIANIQK-RIVGGQETEVHQYPWVAMLLYGGRFYCAASLLNDQFLLTASHCVYGFRK---ERISVRLLEHDRKMSHMQKIDRKVAEVITHPKYNARNYDNDIAIIKLDEPVEFN-EVLHPVCMPTPGRSFKGENGIVTGWGALKVGGPTSDT-LQEVQVPILSQDECRKSR-YGNKITDNMLCGGYDEGGKDSCQGDSGGPL---HIVASGTREHQIAGVVSWGEGCAKAGYPGVYARVNRYGTWIKNLT 358
[Close]
BLAST of Serine protease vs. Ensembl Fly
Match: CG31954 (gene:FBgn0051954 transcript:FBtr0077563)

HSP 1 Score: 150.214 bits (378), Expect = 3.034e-42
Identity = 86/245 (35.10%), Postives = 138/245 (56.33%), Query Frame = 3 
Query:  330 KVFGGWRSMPGEWPWQVQIEREGAHHCGGALIHPNWVVTAAHCTFFFQDLPIEKWRIRAGKTQTNMTEPHEQNVRVKKLIDHPGFTLFTKYHDIALIQLEDPMYFDYKFVSPICLPNPQESF-DDHVCTLSGYGKTESSGEGASTYLLEVNLPIISADTCQEKHCNSNSIYEENLCAGFKEGKRDACTGDSGGPIVCEKLSVNGFKQFVLAGVVSYGSGCGGKDTPGVYTRISSYLDWIEYETGI 1061
            ++ GG R    + P QV ++   +H CGG++I   W++TAAHCT+       ++ ++R G ++   +    Q +RV+K++ H  F      +D +L+QL  P+ FD +    + LP  Q  + D   C +SG+G T++  E +  +L +V +P+++ + C EK+     + E  +CAGF EG +DAC GDSGGP+V E           L GVVS+G GC   D PGVY+R+S   DWI+  +G+
Sbjct:   50 RIVGGHRINITDAPHQVSLQ-TSSHICGGSIISEEWILTAAHCTY---GKTADRLKVRLGTSEFARSG---QLLRVQKIVQHAQFNYTNVDYDFSLLQLAHPIKFD-ETKKAVKLPESQMKYMDGEACFVSGWGNTQNLLE-SREWLRQVEVPLVNQELCSEKYKQYGGVTERMICAGFLEGGKDACQGDSGGPMVSESGE--------LVGVVSWGYGCAKPDYPGVYSRVSFARDWIKEHSGV 277
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BLAST of Serine protease vs. Ensembl Zebrafish
Match: CR352265.1 (pep chromosome:GRCz11:24:21813127:21819010:-1 gene:ENSDARG00000062758.6 transcript:ENSDART00000091096.6 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CR352265.1)

HSP 1 Score: 170.629 bits (431), Expect = 1.315e-49
Identity = 97/264 (36.74%), Postives = 146/264 (55.30%), Query Frame = 3 
Query:  303 CGISNGSKYKVFGGWRSMPGEWPWQV--QIEREGAHHCGGALIHPNWVVTAAHCTFFFQDLPIEK------WRIRAGKTQTNMTEPHEQNVRVKKLIDHPGFTLFTKYHDIALIQLEDPMYFDYKFVSPICLPNPQESFDDHV-CTLSGYGKTESSGEGASTYLLEVNLPIISADTCQEKHCNSNSIYEENLCAGFKEGKRDACTGDSGGPIVCEKLSVNGFKQFVLAGVVSYGSGCGGKDTPGVYTRISSYLDWIEYETGIEV 1067
            CG     + K+ GG  +  G WPWQV  Q+ER G H CG +L+   W+V+AAHC   FQD    K      WR   G    N         ++++++ H  +  FT  +DIAL++L  P++F+ + V P+C+P P   F     C ++G+G     GE A T L E  + II+ +TC + +   +++    LCAG  +G  DAC GDSGGP+VC +      +++ LAG+VS+G GC  ++ PGVYTR+  + DWI  +T  +V
Sbjct:   45 CGTRPRKRAKIVGGTDAQAGSWPWQVSLQMERYG-HVCGASLVASRWLVSAAHC---FQDSDAIKYSDARSWRAYMGMRVMNSVSNAAATRQIRRIVLHSQYDQFTSDYDIALLELSAPVFFN-ELVQPVCVPAPSHVFTSGTSCFVTGWGVLTEEGELA-TLLQEATVNIINHNTCNKMY--DDAVTPRMLCAGNIQGGVDACQGDSGGPLVCLERG----RRWFLAGIVSWGEGCARQNRPGVYTRVIKFTDWIHQQTKGQV 296
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BLAST of Serine protease vs. Ensembl Zebrafish
Match: zgc:165423 (zgc:165423 [Source:ZFIN;Acc:ZDB-GENE-070720-11])

HSP 1 Score: 167.933 bits (424), Expect = 1.765e-46
Identity = 85/240 (35.42%), Postives = 133/240 (55.42%), Query Frame = 3 
Query:  330 KVFGGWRSMPGEWPWQVQIEREGAHHCGGALIHPNWVVTAAHCTFFFQDLPIEKWRIRAGKTQTNMTEPHEQNVRVKKLIDHPGFTLFTKYHDIALIQLEDPMYFDYKFVSPICLPNPQESFDDHVCTLSGYGKTESSGEGASTYLL-EVNLPIISADTCQEKHCNSNSIYEENLCAGFKEGKRDACTGDSGGPIVCEKLSVNGFKQFVLAGVVSYGSGCGGKDTPGVYTRISSYLDWIE 1046
            K+ GG  +  G WPWQ  +   G+H CGG+LI   W+++AAHC  F  +     + +  G+   ++  P+E +  V ++I HP +   T  +D+AL+ L  P+ F   ++ P+CL     +F +    ++G+G  ES     S  +L EVN+PI+  + C   +   +SI    +CAG  +G +D+C GDSGGP+V     +  F  +V AGVVS+G GC   + PGVY R+S Y +WI 
Sbjct:   37 KIVGGTNASAGSWPWQASLHESGSHFCGGSLISDQWILSAAHC--FPSNPNPSDYTVYLGRQSQDLPNPNEVSKSVSQVIVHPLYQGSTHDNDMALLHLSSPVTFS-NYIQPVCLAADGSTFYNDTMWITGWGTIESGVSLPSPQILQEVNVPIVGNNLCNCLYGGGSSITNNMMCAGLMQGGKDSCQGDSGGPMV-----IKSFNTWVQAGVVSFGKGCADPNYPGVYARVSQYQNWIS 268
[Close]
BLAST of Serine protease vs. Ensembl Zebrafish
Match: hpn (hepsin [Source:ZFIN;Acc:ZDB-GENE-141212-373])

HSP 1 Score: 162.54 bits (410), Expect = 2.718e-45
Identity = 94/276 (34.06%), Postives = 141/276 (51.09%), Query Frame = 3 
Query:  303 CGISNGSKYKVFGGWRSMPGEWPWQVQIEREGAHHCGGALIHPNWVVTAAHCTFFFQDLPIEKWRIRAGKTQTNMTEPHEQNVRVKKLIDHPGFTLFTKYH------DIALIQLEDPMYFDYKFVSPICLPN-PQESFDDHVCTLSGYGKTESSGEGASTYLLEVNLPIISADTCQEKHCNSNSIYEENLCAGFKEGKRDACTGDSGGPIVCEKLSVNGFKQFVLAGVVSYGSGCGGKDTPGVYTRISSYLDWIEYETGI-EVSTGKFTMATQFTP 1106
            CG     + ++ GG  +  G WPWQV ++ +G H CGG++I   W+++AAHC F  +     +WR+  G         +     VK ++ H  +  F   +      DIA+I L  P+ F   ++ P+CLP   Q   D  + T++G+G  E  G  A+  L E ++PIIS   C       N +     CAG+++G  D+C GDSGGP V   + ++   ++ L GVVS+G+GC     PGVYTR+S +L WI     + E S G   MA   TP
Sbjct:  154 CGRRMLPEERIVGGVDARQGSWPWQVSLQYDGVHQCGGSIISDRWIISAAHC-FPERYRHASRWRVLMGSIYNTPIRKNVVIAEVKTVVYHSSYLPFVDANIDDNSRDIAVISLTKPLQFT-DYIQPVCLPTYGQRLADGQMGTVTGWGNVEYYGTQANV-LQEAHVPIISDAVCNGPDYYDNQVTTTMFCAGYEKGGTDSCQGDSGGPFVAADV-LSKTSRYRLLGVVSWGTGCAMAKKPGVYTRVSRFLPWISTAMRMYENSPGVHKMARAATP 425
[Close]
BLAST of Serine protease vs. Ensembl Zebrafish
Match: tmprss3a (transmembrane serine protease 3a [Source:ZFIN;Acc:ZDB-GENE-070912-70])

HSP 1 Score: 162.155 bits (409), Expect = 9.225e-45
Identity = 95/267 (35.58%), Postives = 143/267 (53.56%), Query Frame = 3 
Query:  303 CGISNGSKYKVFGGWRSMPGEWPWQVQIEREGAHHCGGALIHPNWVVTAAHCTFFFQDLPIEKWRIRAGKTQTNMTEPHEQNVRVKKLIDHPGFTLFTKYHDIALIQLEDPMYFDYKFVSPICLPNPQESFDD-HVCTLSGYGKTESSGEGASTYLLEVNLPIISADTCQEKHCNSNSIYEENLCAGFKEGKRDACTGDSGGPIVCEKLSVNGFKQFVLAGVVSYGSGCGGKDTPGVYTRISSYLDWIEYETGIEVSTGKFTMATQF 1100
            CG       ++ GG  S  G++PWQV +  +  H CGG++I   W++TAAHC +     P+  W + AG T+  +     +   V+K+I H  +      HDIAL++L  P+ F+   V PICLPN  E F+D  +C +SG+G TE  G+ AS      ++P+IS   C +       +    +CAG+ +G  D+C GDSGGP+ CE  S+     + L G  S+G GC  K+ PGVYTRI+  L WI  +   E      T+++ +
Sbjct:  226 CGSRPKFSARIVGGNLSAEGQFPWQVSLHFQNEHLCGGSIITSRWILTAAHCVYGIA-YPM-YWMVYAGLTELPLNA--VKAFAVEKIIYHSRYRPKGLDHDIALMKLAQPLTFN-GMVEPICLPNFGEQFEDGKMCWISGWGATEDGGD-ASVSQHCASVPLISNKACSQPEVYQGYLTAGMICAGYLDGGTDSCQGDSGGPLACEDSSI-----WKLVGATSWGQGCAEKNKPGVYTRITQSLTWIHLQMEREEILHPLTVSSNY 481
[Close]
BLAST of Serine protease vs. Ensembl Zebrafish
Match: tmprss3a (transmembrane serine protease 3a [Source:ZFIN;Acc:ZDB-GENE-070912-70])

HSP 1 Score: 162.54 bits (410), Expect = 2.336e-44
Identity = 96/257 (37.35%), Postives = 141/257 (54.86%), Query Frame = 3 
Query:  303 CGISNGSKYKVFGGWRSMPGEWPWQVQIEREGAHHCGGALIHPNWVVTAAHCTFFFQDLPIEKWRIRAGKTQTNMTEPHEQNVRVKKLIDHPGFTLFTKYHDIALIQLEDPMYFDYKFVSPICLPNPQESFDD-HVCTLSGYGKTESSGEGASTYLLEVNLPIISADTCQEKHCNSNSIYEENLCAGFKEGKRDACTGDSGGPIVCEKLSVNGFKQFVLAGVVSYGSGCGGKDTPGVYTRISSYLDWIEYETGIEVS 1070
            CG       ++ GG  S  G++PWQV +  +  H CGG++I   W++TAAHC +     P+  W + AG T+  +     +   V+K+I H  +      HDIAL++L  P+ F+   V PICLPN  E F+D  +C +SG+G TE  G+ AS      ++P+IS   C +       +    +CAG+ +G  D+C GDSGGP+ CE  S+     + L G  S+G GC  K+ PGVYTRI+  L WI  +  +EVS
Sbjct:  269 CGSRPKFSARIVGGNLSAEGQFPWQVSLHFQNEHLCGGSIITSRWILTAAHCVYGIA-YPM-YWMVYAGLTELPLNA--VKAFAVEKIIYHSRYRPKGLDHDIALMKLAQPLTFN-GMVEPICLPNFGEQFEDGKMCWISGWGATEDGGD-ASVSQHCASVPLISNKACSQPEVYQGYLTAGMICAGYLDGGTDSCQGDSGGPLACEDSSI-----WKLVGATSWGQGCAEKNKPGVYTRITQSLTWIHLQ--MEVS 512
[Close]
BLAST of Serine protease vs. Ensembl Xenopus
Match: hpn (hepsin [Source:NCBI gene;Acc:100145343])

HSP 1 Score: 176.407 bits (446), Expect = 6.916e-51
Identity = 98/267 (36.70%), Postives = 146/267 (54.68%), Query Frame = 3 
Query:  303 CGISNGSKYKVFGGWRSMPGEWPWQVQIEREGAHHCGGALIHPNWVVTAAHCTFFFQDLPIEKWRIRAGKTQTNMTEPHEQNVRVKKLIDHPGFTLFT------KYHDIALIQLEDPMYFDYKFVSPICLPN-PQESFDDHVCTLSGYGKTESSGEGASTYLLEVNLPIISADTCQEKHCNSNSIYEENLCAGFKEGKRDACTGDSGGPIVCEKLSVNGFKQFVLAGVVSYGSGCGGKDTPGVYTRISSYLDWIEYETGIEVSTGKF 1082
            CG    +  ++ GG  +  G WPWQV +  +GAH CGG+LI   WV+TAAHC F  ++  + +WR+ AG    +   P  + + VK +I H G+  F         +DIAL+ L  P+    +++ P+CLP   Q+  D  +CT+SG+G  +  G+  S  L E ++PIIS+  C +     N I  +  CAG+ EG  DAC GDSGGP VCE  +++   ++ L G+VS+G GC   + PGVY ++  Y  WI     +    GK 
Sbjct:  105 CGRRKLAVDRIVGGQDATLGRWPWQVSLRYDGAHLCGGSLISSEWVLTAAHC-FPERNRIVSQWRVFAGA--VSQLSPRGKLLGVKGIIYHSGYLPFLNPDSEENSNDIALVHLASPVTLS-EYIQPVCLPALGQQIIDGKICTVSGWGNLQYYGQ-QSEILQEASVPIISSSVCNQPEYYMNQITGKMFCAGYAEGGIDACQGDSGGPFVCED-TLSRSSRWRLCGIVSWGIGCAMPNKPGVYAKVDQYQYWIYRAMKVSTEGGKV 365
[Close]
BLAST of Serine protease vs. Ensembl Xenopus
Match: hpn (hepsin [Source:NCBI gene;Acc:100145343])

HSP 1 Score: 174.481 bits (441), Expect = 3.378e-50
Identity = 96/254 (37.80%), Postives = 143/254 (56.30%), Query Frame = 3 
Query:  303 CGISNGSKYKVFGGWRSMPGEWPWQVQIEREGAHHCGGALIHPNWVVTAAHCTFFFQDLPIEKWRIRAGKTQTNMTEPHEQNVRVKKLIDHPGFTLFT------KYHDIALIQLEDPMYFDYKFVSPICLPN-PQESFDDHVCTLSGYGKTESSGEGASTYLLEVNLPIISADTCQEKHCNSNSIYEENLCAGFKEGKRDACTGDSGGPIVCEKLSVNGFKQFVLAGVVSYGSGCGGKDTPGVYTRISSYLDWI 1043
            CG    +  ++ GG  +  G WPWQV +  +GAH CGG+LI   WV+TAAHC F  ++  + +WR+ AG    +   P  + + VK +I H G+  F         +DIAL+ L  P+    +++ P+CLP   Q+  D  +CT+SG+G  +  G+  S  L E ++PIIS+  C +     N I  +  CAG+ EG  DAC GDSGGP VCE  +++   ++ L G+VS+G GC   + PGVY ++  Y  WI
Sbjct:  104 CGRRKLAVDRIVGGQDATLGRWPWQVSLRYDGAHLCGGSLISSEWVLTAAHC-FPERNRIVSQWRVFAGA--VSQLSPRGKLLGVKGIIYHSGYLPFLNPDSEENSNDIALVHLASPVTLS-EYIQPVCLPALGQQIIDGKICTVSGWGNLQYYGQ-QSEILQEASVPIISSSVCNQPEYYMNQITGKMFCAGYAEGGIDACQGDSGGPFVCED-TLSRSSRWRLCGIVSWGIGCAMPNKPGVYAKVDQYQYWI 351
[Close]
BLAST of Serine protease vs. Ensembl Xenopus
Match: hpn (hepsin [Source:NCBI gene;Acc:100145343])

HSP 1 Score: 174.866 bits (442), Expect = 3.564e-50
Identity = 96/254 (37.80%), Postives = 143/254 (56.30%), Query Frame = 3 
Query:  303 CGISNGSKYKVFGGWRSMPGEWPWQVQIEREGAHHCGGALIHPNWVVTAAHCTFFFQDLPIEKWRIRAGKTQTNMTEPHEQNVRVKKLIDHPGFTLFT------KYHDIALIQLEDPMYFDYKFVSPICLPN-PQESFDDHVCTLSGYGKTESSGEGASTYLLEVNLPIISADTCQEKHCNSNSIYEENLCAGFKEGKRDACTGDSGGPIVCEKLSVNGFKQFVLAGVVSYGSGCGGKDTPGVYTRISSYLDWI 1043
            CG    +  ++ GG  +  G WPWQV +  +GAH CGG+LI   WV+TAAHC F  ++  + +WR+ AG    +   P  + + VK +I H G+  F         +DIAL+ L  P+    +++ P+CLP   Q+  D  +CT+SG+G  +  G+  S  L E ++PIIS+  C +     N I  +  CAG+ EG  DAC GDSGGP VCE  +++   ++ L G+VS+G GC   + PGVY ++  Y  WI
Sbjct:  120 CGRRKLAVDRIVGGQDATLGRWPWQVSLRYDGAHLCGGSLISSEWVLTAAHC-FPERNRIVSQWRVFAGA--VSQLSPRGKLLGVKGIIYHSGYLPFLNPDSEENSNDIALVHLASPVTLS-EYIQPVCLPALGQQIIDGKICTVSGWGNLQYYGQ-QSEILQEASVPIISSSVCNQPEYYMNQITGKMFCAGYAEGGIDACQGDSGGPFVCED-TLSRSSRWRLCGIVSWGIGCAMPNKPGVYAKVDQYQYWI 367
[Close]
BLAST of Serine protease vs. Ensembl Xenopus
Match: hpn (hepsin [Source:NCBI gene;Acc:100145343])

HSP 1 Score: 174.866 bits (442), Expect = 7.431e-50
Identity = 96/254 (37.80%), Postives = 143/254 (56.30%), Query Frame = 3 
Query:  303 CGISNGSKYKVFGGWRSMPGEWPWQVQIEREGAHHCGGALIHPNWVVTAAHCTFFFQDLPIEKWRIRAGKTQTNMTEPHEQNVRVKKLIDHPGFTLFT------KYHDIALIQLEDPMYFDYKFVSPICLPN-PQESFDDHVCTLSGYGKTESSGEGASTYLLEVNLPIISADTCQEKHCNSNSIYEENLCAGFKEGKRDACTGDSGGPIVCEKLSVNGFKQFVLAGVVSYGSGCGGKDTPGVYTRISSYLDWI 1043
            CG    +  ++ GG  +  G WPWQV +  +GAH CGG+LI   WV+TAAHC F  ++  + +WR+ AG    +   P  + + VK +I H G+  F         +DIAL+ L  P+    +++ P+CLP   Q+  D  +CT+SG+G  +  G+  S  L E ++PIIS+  C +     N I  +  CAG+ EG  DAC GDSGGP VCE  +++   ++ L G+VS+G GC   + PGVY ++  Y  WI
Sbjct:  153 CGRRKLAVDRIVGGQDATLGRWPWQVSLRYDGAHLCGGSLISSEWVLTAAHC-FPERNRIVSQWRVFAGA--VSQLSPRGKLLGVKGIIYHSGYLPFLNPDSEENSNDIALVHLASPVTLS-EYIQPVCLPALGQQIIDGKICTVSGWGNLQYYGQ-QSEILQEASVPIISSSVCNQPEYYMNQITGKMFCAGYAEGGIDACQGDSGGPFVCED-TLSRSSRWRLCGIVSWGIGCAMPNKPGVYAKVDQYQYWI 400
[Close]
BLAST of Serine protease vs. Ensembl Xenopus
Match: ENSXETT00000015569.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:9:2816071:2829750:1 gene:ENSXETG00000010028.1 transcript:ENSXETT00000015569.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 168.318 bits (425), Expect = 3.450e-48
Identity = 95/280 (33.93%), Postives = 154/280 (55.00%), Query Frame = 3 
Query:  330 KVFGGWRSMPGEWPWQVQIEREGAHHCGGALIHPNWVVTAAHCTFFFQDLPIEKWRIRAGKTQTNMTEPHEQNVRVKKLIDHPGFTLFTKYHDIALIQLEDPMYFDYKFVSPICLPNPQESF-DDHVCTLSGYGKTESSGEGASTY-LLEVNLPIISADTCQEK-HCNSN------SIYEENLCAGFKEGKRDACTGDSGGPIVCEKLSVNGFKQFVLAGVVSYGSGCGGKDTPGVYTRISSYLDWIEYETGIEVSTGKFTMATQFTPEAVKRVVTDKCK 1142
            ++ GG  ++ GEWPWQV I  + +H CGG+L+  NWVV+AAHC  F +   IE  ++  G             +RVK++I +P +T      DIA++++E P+ +   ++ PIC+P   E F    +C ++G+G  +S    +  Y L EV +P+++A +C    H NS+       ++++ +CAG+ EG++DAC GDSGGP+ C+         + L G+VS+G GC   + PGVYT++SS+  WI     + VS       T  TP ++    +   K
Sbjct:   35 RIVGGNNAVFGEWPWQVSIVYQNSHICGGSLVSSNWVVSAAHC--FPRSYKIENMQVLLGCFALMNLTSDAVIIRVKRVITYPLYTGEGSSGDIAMVEMESPVTYS-SYILPICIPLTNEDFPSGKMCWVTGWGNIQSDVSLSPPYPLQEVEVPLVNASSCDTMYHYNSDLNPATQLVHDDMICAGYPEGQKDACQGDSGGPLACKS-----GNYWFLTGIVSWGDGCAQPNRPGVYTKVSSFSSWINQYLVLNVS------VTTKTPHSISLANSSSTK 300
[Close]
BLAST of Serine protease vs. Ensembl Mouse
Match: Hpn (hepsin [Source:MGI Symbol;Acc:MGI:1196620])

HSP 1 Score: 178.333 bits (451), Expect = 2.450e-51
Identity = 97/254 (38.19%), Postives = 145/254 (57.09%), Query Frame = 3 
Query:  303 CGISNGSKYKVFGGWRSMPGEWPWQVQIEREGAHHCGGALIHPNWVVTAAHCTFFFQDLPIEKWRIRAGKTQTNMTEPHEQNVRVKKLIDHPGF------TLFTKYHDIALIQLEDPMYFDYKFVSPICLPNPQESF-DDHVCTLSGYGKTESSGEGASTYLLEVNLPIISADTCQEKHCNSNSIYEENLCAGFKEGKRDACTGDSGGPIVCEKLSVNGFKQFVLAGVVSYGSGCGGKDTPGVYTRISSYLDWI 1043
            CG       ++ GG  S  G WPWQV +  +G H CGG+L+  +WV+TAAHC F  ++  + +WR+ AG      T PH   + V+ +I H G+      T+    +DIAL+ L   +    +++ P+CLP   ++  D  VCT++G+G T+  G+ A   L E  +PIIS + C       N I  +  CAG+ EG  DAC GDSGGP VCE  S++G  ++ L G+VS+G+GC     PGVYT+++ + +WI
Sbjct:  152 CGRRKLPVDRIVGGQDSSLGRWPWQVSLRYDGTHLCGGSLLSGDWVLTAAHC-FPERNRVLSRWRVFAGAVA--RTSPHAVQLGVQAVIYHGGYLPFRDPTIDENSNDIALVHLSSSLPLT-EYIQPVCLPAAGQALVDGKVCTVTGWGNTQFYGQQA-MVLQEARVPIISNEVCNSPDFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCED-SISGTSRWRLCGIVSWGTGCALARKPGVYTKVTDFREWI 399
[Close]
BLAST of Serine protease vs. Ensembl Mouse
Match: Hpn (hepsin [Source:MGI Symbol;Acc:MGI:1196620])

HSP 1 Score: 178.333 bits (451), Expect = 3.684e-51
Identity = 97/254 (38.19%), Postives = 145/254 (57.09%), Query Frame = 3 
Query:  303 CGISNGSKYKVFGGWRSMPGEWPWQVQIEREGAHHCGGALIHPNWVVTAAHCTFFFQDLPIEKWRIRAGKTQTNMTEPHEQNVRVKKLIDHPGF------TLFTKYHDIALIQLEDPMYFDYKFVSPICLPNPQESF-DDHVCTLSGYGKTESSGEGASTYLLEVNLPIISADTCQEKHCNSNSIYEENLCAGFKEGKRDACTGDSGGPIVCEKLSVNGFKQFVLAGVVSYGSGCGGKDTPGVYTRISSYLDWI 1043
            CG       ++ GG  S  G WPWQV +  +G H CGG+L+  +WV+TAAHC F  ++  + +WR+ AG      T PH   + V+ +I H G+      T+    +DIAL+ L   +    +++ P+CLP   ++  D  VCT++G+G T+  G+ A   L E  +PIIS + C       N I  +  CAG+ EG  DAC GDSGGP VCE  S++G  ++ L G+VS+G+GC     PGVYT+++ + +WI
Sbjct:  172 CGRRKLPVDRIVGGQDSSLGRWPWQVSLRYDGTHLCGGSLLSGDWVLTAAHC-FPERNRVLSRWRVFAGAVA--RTSPHAVQLGVQAVIYHGGYLPFRDPTIDENSNDIALVHLSSSLPLT-EYIQPVCLPAAGQALVDGKVCTVTGWGNTQFYGQQA-MVLQEARVPIISNEVCNSPDFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCED-SISGTSRWRLCGIVSWGTGCALARKPGVYTKVTDFREWI 419
[Close]
BLAST of Serine protease vs. Ensembl Mouse
Match: Hpn (hepsin [Source:MGI Symbol;Acc:MGI:1196620])

HSP 1 Score: 178.333 bits (451), Expect = 5.677e-51
Identity = 97/254 (38.19%), Postives = 145/254 (57.09%), Query Frame = 3 
Query:  303 CGISNGSKYKVFGGWRSMPGEWPWQVQIEREGAHHCGGALIHPNWVVTAAHCTFFFQDLPIEKWRIRAGKTQTNMTEPHEQNVRVKKLIDHPGF------TLFTKYHDIALIQLEDPMYFDYKFVSPICLPNPQESF-DDHVCTLSGYGKTESSGEGASTYLLEVNLPIISADTCQEKHCNSNSIYEENLCAGFKEGKRDACTGDSGGPIVCEKLSVNGFKQFVLAGVVSYGSGCGGKDTPGVYTRISSYLDWI 1043
            CG       ++ GG  S  G WPWQV +  +G H CGG+L+  +WV+TAAHC F  ++  + +WR+ AG      T PH   + V+ +I H G+      T+    +DIAL+ L   +    +++ P+CLP   ++  D  VCT++G+G T+  G+ A   L E  +PIIS + C       N I  +  CAG+ EG  DAC GDSGGP VCE  S++G  ++ L G+VS+G+GC     PGVYT+++ + +WI
Sbjct:  181 CGRRKLPVDRIVGGQDSSLGRWPWQVSLRYDGTHLCGGSLLSGDWVLTAAHC-FPERNRVLSRWRVFAGAVA--RTSPHAVQLGVQAVIYHGGYLPFRDPTIDENSNDIALVHLSSSLPLT-EYIQPVCLPAAGQALVDGKVCTVTGWGNTQFYGQQA-MVLQEARVPIISNEVCNSPDFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCED-SISGTSRWRLCGIVSWGTGCALARKPGVYTKVTDFREWI 428
[Close]
BLAST of Serine protease vs. Ensembl Mouse
Match: Prss27 (protease, serine 27 [Source:MGI Symbol;Acc:MGI:2450123])

HSP 1 Score: 174.096 bits (440), Expect = 1.269e-50
Identity = 92/248 (37.10%), Postives = 141/248 (56.85%), Query Frame = 3 
Query:  330 KVFGGWRSMPGEWPWQVQIEREGAHHCGGALIHPNWVVTAAHCTFFFQDLPIEKWRIRAGKTQTNMTEPHEQNVRVKKLIDHPGFTLFTKYHDIALIQLEDPMYFDYKFVSPICLPNPQESFDDHV-CTLSGYGKTESSGEGASTYLLE-VNLPIISADTCQ-------EKHCNSNSIYEENLCAGFKEGKRDACTGDSGGPIVCEKLSVNGFKQFVLAGVVSYGSGCGGKDTPGVYTRISSYLDWIE 1046
            ++ GG  ++ GEWPWQV I+R G H CGG+LI P WV+TAAHC     D+ I  +++  G  +     PH   V VK++  +P +       D+AL++L+ P+ F   ++ P+CLP+P   F+  + C ++G+G         +  +L+ + +PII    C        E      +I ++ LCAGF EGK+DAC GDSGGP+VC        + +V AGV+S+G GC  ++ PGVY R++S+  WI 
Sbjct:   37 RMVGGENALEGEWPWQVSIQRNGIHFCGGSLIAPTWVLTAAHCFSNTSDISI--YQVLLGALKLQQPGPHALYVPVKQVKSNPQYQGMASSADVALVELQGPVTFT-NYILPVCLPDPSVIFESGMNCWVTGWGSPSEQDRLPNPRVLQKLAVPIIDTPKCNLLYNKDVESDFQLKTIKDDMLCAGFAEGKKDACKGDSGGPLVCLV-----DQSWVQAGVISWGEGCARRNRPGVYIRVTSHHKWIH 276
[Close]
BLAST of Serine protease vs. Ensembl Mouse
Match: Tmprss3 (transmembrane protease, serine 3 [Source:MGI Symbol;Acc:MGI:2155445])

HSP 1 Score: 177.563 bits (449), Expect = 1.282e-50
Identity = 102/261 (39.08%), Postives = 150/261 (57.47%), Query Frame = 3 
Query:  297 NKCGISNGSKYKVFGGWRSMPGEWPWQVQIEREGAHHCGGALIHPNWVVTAAHCTFFFQDLPIEK-WRIRAGKTQTNMTEPHEQNVRVKKLIDHPGFTLFTKYHDIALIQLEDPMYFDYKFVSPICLPNPQESF-DDHVCTLSGYGKTESSGEGASTYLLEVNLPIISADTCQEKHCNSNSIYEENLCAGFKEGKRDACTGDSGGPIVCEKLSVNGFKQFVLAGVVSYGSGCGGKDTPGVYTRISSYLDWIEYETGIEVST 1073
            + CG   G   ++ GG  S   +WPWQV ++ +G H CGG++I P W+VTAAHC +   DL   K W ++ G     M  P   ++ V+K+I H  +      +DIAL++L +P+ FD + + PICLPN +E+F D  +C  SG+G TE  G+ AS  L    +P+IS   C  +      I    LCAG+ +G  D+C GDSGGP+VC++      + + L G  S+G GC   + PGVYTRI+S+LDWI  +   ++ T
Sbjct:  205 SACGTRTGYSPRIVGGNMSSLTQWPWQVSLQFQGYHLCGGSIITPLWIVTAAHCVY---DLYHPKSWTVQVGLVSL-MDSPVPSHL-VEKIIYHSKYKPKRLGNDIALMKLSEPLTFD-ETIQPICLPNSEENFPDGKLCWTSGWGATEDGGD-ASPVLNHAAVPLISNKICNHRDVYGGIISPSMLCAGYLKGGVDSCQGDSGGPLVCQER-----RLWKLVGATSFGIGCAEVNKPGVYTRITSFLDWIHEQLERDLKT 453
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BLAST of Serine protease vs. UniProt/SwissProt
Match: sp|Q6BEA2|PRS27_RAT (Serine protease 27 OS=Rattus norvegicus OX=10116 GN=Prss27 PE=2 SV=1)

HSP 1 Score: 179.874 bits (455), Expect = 5.572e-52
Identity = 94/247 (38.06%), Postives = 142/247 (57.49%), Query Frame = 3 
Query:  330 KVFGGWRSMPGEWPWQVQIEREGAHHCGGALIHPNWVVTAAHCTFFFQDLPIEKWRIRAGKTQTNMTEPHEQNVRVKKLIDHPGFTLFTKYHDIALIQLEDPMYFDYKFVSPICLPNPQESFDDHV-CTLSGYGKTESSGEGASTYLLE-VNLPIISADTCQ-------EKHCNSNSIYEENLCAGFKEGKRDACTGDSGGPIVCEKLSVNGFKQFVLAGVVSYGSGCGGKDTPGVYTRISSYLDWI 1043
            ++ GG  ++ GEWPWQV I+R GAH CGG+LI P WV+TAAHC     D+ I  +++  G  +     PH   V VK++  HP +       D+AL++L+ P+ F  K++ P+CLP+P   F   + C ++G+G         +  +L+ + +P+I    C        E      +I ++ LCAGF EGK+DAC GDSGGP+VC        + +V AGV+S+G GC  ++ PGVY R++S+  WI
Sbjct:   37 RMVGGEDALEGEWPWQVSIQRNGAHFCGGSLIAPTWVLTAAHCFSNTSDISI--YQVLLGALKLQQPGPHALYVPVKRVKSHPEYQGMASSADVALVELQVPVTFT-KYILPVCLPDPSVVFKSGMNCWVTGWGSPSEQDRLPNPRILQKLAVPLIDTPKCNLLYSKDAEADIQLKTIKDDMLCAGFAEGKKDACKGDSGGPLVCLV-----DQSWVQAGVISWGEGCARRNRPGVYIRVASHYQWI 275
[Close]
BLAST of Serine protease vs. UniProt/SwissProt
Match: sp|Q5R5E8|HEPS_PONAB (Serine protease hepsin OS=Pongo abelii OX=9601 GN=HPN PE=2 SV=1)

HSP 1 Score: 179.104 bits (453), Expect = 9.537e-51
Identity = 96/254 (37.80%), Postives = 144/254 (56.69%), Query Frame = 3 
Query:  303 CGISNGSKYKVFGGWRSMPGEWPWQVQIEREGAHHCGGALIHPNWVVTAAHCTFFFQDLPIEKWRIRAGKTQTNMTEPHEQNVRVKKLIDHPGFTLFT------KYHDIALIQLEDPMYFDYKFVSPICLPNPQESF-DDHVCTLSGYGKTESSGEGASTYLLEVNLPIISADTCQEKHCNSNSIYEENLCAGFKEGKRDACTGDSGGPIVCEKLSVNGFKQFVLAGVVSYGSGCGGKDTPGVYTRISSYLDWI 1043
            CG       ++ GG  +  G WPWQV +  +GAH CGG+L+  +WV+TAAHC F  ++  + +WR+ AG        PH   + V+ ++ H G+  F         +DIAL+ L  P+    +++ P+CLP   ++  D  +CT++G+G T+  G+ A   L E  +PIIS D C       N I  +  CAG+ EG  DAC GDSGGP VCE  S++   ++ L G+VS+G+GC     PGVYT++S + +WI
Sbjct:  153 CGRRKLPVDRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHC-FPERNRVLSRWRVFAGAVA--QASPHGLQLAVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLT-EYIQPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGV-LQEARVPIISNDVCNGADFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCED-SISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDFREWI 400
[Close]
BLAST of Serine protease vs. UniProt/SwissProt
Match: sp|P05981|HEPS_HUMAN (Serine protease hepsin OS=Homo sapiens OX=9606 GN=HPN PE=1 SV=1)

HSP 1 Score: 178.718 bits (452), Expect = 1.279e-50
Identity = 96/254 (37.80%), Postives = 144/254 (56.69%), Query Frame = 3 
Query:  303 CGISNGSKYKVFGGWRSMPGEWPWQVQIEREGAHHCGGALIHPNWVVTAAHCTFFFQDLPIEKWRIRAGKTQTNMTEPHEQNVRVKKLIDHPGFTLFT------KYHDIALIQLEDPMYFDYKFVSPICLPNPQESF-DDHVCTLSGYGKTESSGEGASTYLLEVNLPIISADTCQEKHCNSNSIYEENLCAGFKEGKRDACTGDSGGPIVCEKLSVNGFKQFVLAGVVSYGSGCGGKDTPGVYTRISSYLDWI 1043
            CG       ++ GG  +  G WPWQV +  +GAH CGG+L+  +WV+TAAHC F  ++  + +WR+ AG        PH   + V+ ++ H G+  F         +DIAL+ L  P+    +++ P+CLP   ++  D  +CT++G+G T+  G+ A   L E  +PIIS D C       N I  +  CAG+ EG  DAC GDSGGP VCE  S++   ++ L G+VS+G+GC     PGVYT++S + +WI
Sbjct:  153 CGRRKLPVDRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHC-FPERNRVLSRWRVFAGAVA--QASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLT-EYIQPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGV-LQEARVPIISNDVCNGADFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCED-SISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDFREWI 400
[Close]
BLAST of Serine protease vs. UniProt/SwissProt
Match: sp|O35453|HEPS_MOUSE (Serine protease hepsin OS=Mus musculus OX=10090 GN=Hpn PE=1 SV=3)

HSP 1 Score: 178.333 bits (451), Expect = 2.577e-50
Identity = 97/254 (38.19%), Postives = 145/254 (57.09%), Query Frame = 3 
Query:  303 CGISNGSKYKVFGGWRSMPGEWPWQVQIEREGAHHCGGALIHPNWVVTAAHCTFFFQDLPIEKWRIRAGKTQTNMTEPHEQNVRVKKLIDHPGF------TLFTKYHDIALIQLEDPMYFDYKFVSPICLPNPQESF-DDHVCTLSGYGKTESSGEGASTYLLEVNLPIISADTCQEKHCNSNSIYEENLCAGFKEGKRDACTGDSGGPIVCEKLSVNGFKQFVLAGVVSYGSGCGGKDTPGVYTRISSYLDWI 1043
            CG       ++ GG  S  G WPWQV +  +G H CGG+L+  +WV+TAAHC F  ++  + +WR+ AG      T PH   + V+ +I H G+      T+    +DIAL+ L   +    +++ P+CLP   ++  D  VCT++G+G T+  G+ A   L E  +PIIS + C       N I  +  CAG+ EG  DAC GDSGGP VCE  S++G  ++ L G+VS+G+GC     PGVYT+++ + +WI
Sbjct:  172 CGRRKLPVDRIVGGQDSSLGRWPWQVSLRYDGTHLCGGSLLSGDWVLTAAHC-FPERNRVLSRWRVFAGAVA--RTSPHAVQLGVQAVIYHGGYLPFRDPTIDENSNDIALVHLSSSLPLT-EYIQPVCLPAAGQALVDGKVCTVTGWGNTQFYGQQA-MVLQEARVPIISNEVCNSPDFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCED-SISGTSRWRLCGIVSWGTGCALARKPGVYTKVTDFREWI 419
[Close]
BLAST of Serine protease vs. UniProt/SwissProt
Match: sp|Q8BJR6|PRS27_MOUSE (Serine protease 27 OS=Mus musculus OX=10090 GN=Prss27 PE=2 SV=1)

HSP 1 Score: 174.096 bits (440), Expect = 8.880e-50
Identity = 92/248 (37.10%), Postives = 141/248 (56.85%), Query Frame = 3 
Query:  330 KVFGGWRSMPGEWPWQVQIEREGAHHCGGALIHPNWVVTAAHCTFFFQDLPIEKWRIRAGKTQTNMTEPHEQNVRVKKLIDHPGFTLFTKYHDIALIQLEDPMYFDYKFVSPICLPNPQESFDDHV-CTLSGYGKTESSGEGASTYLLE-VNLPIISADTCQ-------EKHCNSNSIYEENLCAGFKEGKRDACTGDSGGPIVCEKLSVNGFKQFVLAGVVSYGSGCGGKDTPGVYTRISSYLDWIE 1046
            ++ GG  ++ GEWPWQV I+R G H CGG+LI P WV+TAAHC     D+ I  +++  G  +     PH   V VK++  +P +       D+AL++L+ P+ F   ++ P+CLP+P   F+  + C ++G+G         +  +L+ + +PII    C        E      +I ++ LCAGF EGK+DAC GDSGGP+VC        + +V AGV+S+G GC  ++ PGVY R++S+  WI 
Sbjct:   37 RMVGGENALEGEWPWQVSIQRNGIHFCGGSLIAPTWVLTAAHCFSNTSDISI--YQVLLGALKLQQPGPHALYVPVKQVKSNPQYQGMASSADVALVELQGPVTFT-NYILPVCLPDPSVIFESGMNCWVTGWGSPSEQDRLPNPRVLQKLAVPIIDTPKCNLLYNKDVESDFQLKTIKDDMLCAGFAEGKKDACKGDSGGPLVCLV-----DQSWVQAGVISWGEGCARRNRPGVYIRVTSHHKWIH 276
[Close]
BLAST of Serine protease vs. TrEMBL
Match: A0S0P9 (Serine protease CFSP2 OS=Azumapecten farreri OX=106299 PE=2 SV=1)

HSP 1 Score: 201.445 bits (511), Expect = 1.334e-57
Identity = 108/249 (43.37%), Postives = 149/249 (59.84%), Query Frame = 3 
Query:  303 CGISNGS-KYKVFGGWRSMPGEWPWQVQIEREGAHHCGGALIHPNWVVTAAHCTFFFQDLPIEKWRIRAGKTQTNMTEPHEQNVRVKKLIDHPGFTLFTKYHDIALIQLEDPMYFDYKFVSPICLPNPQESFDDHVCTLSGYGKTESSGEGASTYLLEVNLPIISADTCQEKHCNSNSIYEENLCAGFKEGKRDACTGDSGGPIVCEKLSVNGFKQFVLAGVVSYGSGCGGKDTPGVYTRISSYLDWIE 1046
            CG+   S  +K+ GG  +  GE+PWQV +   G H CGG LI   WVVTAAHC   FQD     W +  G          + +  +  +I H  +     ++DIALI+L+ P+     +V   CLP+P E FD++VCT +G+G T   G+G S YL EV++PIIS + C   +   N++Y  N+CAGF EG +DAC GDSGGP+ C+K   NG  Q+ LAG+ S+G GC  +  PGVYTR+SS+L WI+
Sbjct:   94 CGLPAVSGNHKIVGGTTATHGEYPWQVSLRYGGHHMCGGTLIDNQWVVTAAHC---FQDTSRSHWTVAVGVQDRGHVYTSQVHTAI-NIITHEYYDHSRNHNDIALIKLDKPVDTTTTYVRTACLPDPNEDFDNNVCTATGWGATHEGGQG-SRYLREVDVPIISNNMCH--YYMGNTVYSSNICAGFSEGGKDACQGDSGGPLTCKK---NG--QWKLAGITSWGYGCAQRHAPGVYTRVSSFLYWIQ 330
[Close]
BLAST of Serine protease vs. TrEMBL
Match: A0A0S2PIU1 (Serine protease OS=Haliotis discus hannai OX=42344 PE=2 SV=1)

HSP 1 Score: 199.904 bits (507), Expect = 2.580e-57
Identity = 105/251 (41.83%), Postives = 152/251 (60.56%), Query Frame = 3 
Query:  294 NNKCGISNGSKYKVFGGWRSMPGEWPWQVQIEREGAHHCGGALIHPNWVVTAAHCTFFFQDLPIEKWRIRAGKTQTNMTEPHEQNVRVKKLIDHPGFTLFTKYHDIALIQLEDPMYFDYKFVSPICLPNPQESFDDHVCTLSGYGKTESSGEGASTYLLEVNLPIISADTCQEKHCNSNSIYEENLCAGFKEGKRDACTGDSGGPIVCEKLSVNGFKQFVLAGVVSYGSGCGGKDTPGVYTRISSYLDWIE 1046
            N  CG+   S+  + GG R++ GE+PWQV ++    H CGG LI   W+ TAAHC   F+D  +  W +  G    N     +Q  ++  +I H  F   T  HDIAL++L  P+  + + + P CLP   E+FD+ VCT++G+G T + G  +  YL +VN+P+I+   C  K+   N +++ N+CAG   G +DAC GDSGGP+VC+  SV     + LAG+VS+G GCG + TPGVYTR+SS+L WIE
Sbjct:   77 NGHCGVPEVSR--IVGGSRAVAGEFPWQVSLQYNQGHMCGGTLIDDQWIATAAHC---FEDTNLGNWDVVMGGID-NYNVYQKQVHKIANIIRHASFNSRTNAHDIALVKLSQPIA-EGRLLKPACLPASGENFDNVVCTVTGWGSTHTDGP-SRRYLEKVNIPVITNSMC--KYYLGNVVFDHNICAGLTAGGKDACQGDSGGPLVCKTGSV-----WKLAGIVSWGYGCGDRATPGVYTRVSSFLSWIE 312
[Close]
BLAST of Serine protease vs. TrEMBL
Match: A0A210QXI3 (Transmembrane protease serine 2 OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT22910 PE=3 SV=1)

HSP 1 Score: 196.052 bits (497), Expect = 1.081e-55
Identity = 106/265 (40.00%), Postives = 154/265 (58.11%), Query Frame = 3 
Query:  258 KPLNKNEKPQKRNNKCGISNGS-KYKVFGGWRSMPGEWPWQVQIEREGAHHCGGALIHPNWVVTAAHCTFFFQDLPIEKWRIRAG-KTQTNMTEPHEQNVRVKKLIDHPGFTLFTKYHDIALIQLEDPMYFDYKFVSPICLPNPQESFDDHVCTLSGYGKTESSGEGASTYLLEVNLPIISADTCQEKHCNSNSIYEENLCAGFKEGKRDACTGDSGGPIVCEKLSVNGFKQFVLAGVVSYGSGCGGKDTPGVYTRISSYLDWIE 1046
             P +        + +CG+   S  +K+ GG  +  GE+PWQV +   G H CGG LI   WVVTAAHC   FQD     W +  G + ++++      N  +  ++ H  +     ++DIALI+L+ P+     +V   CLP+P E+FD++VCT +G+G     G+G S YL EV++PII    C   +   NSIY  NLCAG+ +G +DAC GDSGGP+ C+K  V     + LAG+ S+G GC  ++ PGVYTR+SS+L WI+
Sbjct:   74 APSHGTGSHTTSSGQCGVPAVSGNHKIVGGTVATHGEYPWQVSLRYGGQHMCGGTLIDSQWVVTAAHC---FQDTSKHYWTVAVGVQDRSHIYSSQVHNAIL--VLTHEHYDHSRNHNDIALIKLDKPVDTTTTYVKTACLPDPNENFDNNVCTATGWGALHEGGQG-SRYLEEVDVPIIPNSRC--NYYMGNSIYTSNLCAGYSQGGKDACQGDSGGPLTCKKNGV-----WKLAGITSWGYGCAQRNAPGVYTRVSSFLSWIQ 325
[Close]
BLAST of Serine protease vs. TrEMBL
Match: A0A267H9B2 (Peptidase S1 domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig019102g1 PE=3 SV=1)

HSP 1 Score: 192.2 bits (487), Expect = 6.871e-54
Identity = 118/358 (32.96%), Postives = 181/358 (50.56%), Query Frame = 3 
Query:   39 IFPMSRTKCLSFFLIIFYVSQVLGYKDETP--ICYRKYDGVCV-LKSDPCPFKGEFVEVKPEENEKICREESHRCCKPLNKNEKPQKRN------NKCGISNGSKYKVFGGWRSMPGEWPWQVQI------------EREGAHHCGGALIHPNWVVTAAHCTFFFQDLPIEKWRIRAGKTQTNMTEPHEQNVRVKKLIDHPGFTLFTKYHDIALIQLEDPMYFDYKFVSPICLPNPQESFDDHVCTLSGYGKTESSGEGASTYLLEVNLPIISADTCQEKHC-NSNSIYEENLCAGFKEGKRDACTGDSGGPIVCEKLSVNGFKQFVLAGVVSYGSGCGGKDTPGVYTRISSYLDWIE 1046
            ++  S     S   +  Y +   G  + T    C++ + GVCV   SD CPF+  +          +     + CC P  + E+  +R+      N+          V GG  ++ G+WPW  QI            +     HCGG L+HP WV++A HC F + D   E + +R G T        E NV   +++ H  F      +D+AL++L+ P       V PICLP P E+FD+ + +++G+G TE S    +  L+E  LP++S   C+E +   S  +Y EN+CAGF  G+RDACTGDSGGP++     +NG   +++AG+VS+G GCG    PGVY R+S+Y +W+ 
Sbjct:   15 MYTASAALVYSLVFLWTYSAPADGATNGTSNSTCWKVFAGVCVKTGSDGCPFENAWFS-------WLHCPAGYHCCVPPKRPEQHIERHPIVPCGNRSSTGAADVSLVIGGHLAVAGDWPWLAQILVSRDLSAKTAKDATPRQHCGGVLVHPQWVLSAGHC-FAWADAS-ETFSVRLGHTAAGDISVQEFNV--SRVVVHERFFQPIYSNDVALLKLDKPAQL-LNSVEPICLPEPGEAFDNSIGSVAGWGATEDSD--VADRLMETQLPVLSNTRCKELYAGTSRPVYAENICAGFLAGERDACTGDSGGPLM-----INGQDLWLVAGLVSHGDGCGQAKRPGVYARMSAYAEWVR 353
[Close]
BLAST of Serine protease vs. TrEMBL
Match: B5B2J9 (Serine protease OS=Pinctada fucata OX=50426 PE=2 SV=1)

HSP 1 Score: 191.43 bits (485), Expect = 7.954e-54
Identity = 110/309 (35.60%), Postives = 162/309 (52.43%), Query Frame = 3 
Query:  129 ICYRKYDGVCVLKSDPCPFKGEFVEVKPEENEKICREESHRCCKPLNKNEKPQKRNNKCGISNG---SKYKVFGGWRSMPGEWPWQVQIEREGAHHCGGALIHPNWVVTAAHCTFFFQDLPIEKWRIRAGKTQTNMTEPHEQNVRVKKLIDHPGFTLFTKYHDIALIQLEDPMYFDYKFVSPICLPNPQESFDDHVCTLSGYGKTESSGEGASTYLLEVNLPIISADTCQEKHCNSNSIYEENLCAGFKEGKRDACTGDSGGPIVCEKLSVNGFKQFVLAGVVSYGSGCGGKDTPGVYTRISSYLDWIE 1046
            +C+ +Y G CV         G +        +++C       C P      P  +  +CG+S      + K+ GG  + PGE+PWQV +   G H CGG ++   WV+TAAHC  F  +     W +  G+    + E +E   +V+ L  H  F      +DIALI+L +P+  D  +V P+C+PN  ESFD  +CT++G+G + S G G    L + ++P++S + C   +    +I    LCAG K G  D+C GDSGGP+VC+K   NG    V  G+VS+G  C    TPGVYTR+ SYLDW+ 
Sbjct:   22 LCHERYGGTCVNMYYNSCLSGHYYSTNGCAFQEMC-------CIPPKHTIYPPLKQGQCGVSTPVPERQTKIVGGKIAAPGEFPWQVSMRSNGHHVCGGIMVGDQWVMTAAHC--FKTNKNPYAWTVVLGEHDRAVLEGYEILEKVETLFIHSHFDPAQFLNDIALIKLGNPVTVDTAYVRPVCIPNKNESFDGMICTITGWGASHSGGVGTHN-LYKADVPLLSNEVC--SYLMDRTIPNTELCAGRKRGGVDSCQGDSGGPMVCKK---NGVWNIV--GIVSWGYSCAQAYTPGVYTRVQSYLDWVH 313
[Close]
BLAST of Serine protease vs. Ensembl Cavefish
Match: zgc:92313 (serine protease 33-like [Source:NCBI gene;Acc:111192381])

HSP 1 Score: 174.096 bits (440), Expect = 9.939e-51
Identity = 104/278 (37.41%), Postives = 157/278 (56.47%), Query Frame = 3 
Query:  225 KICREESHRCCKPLNKNEKPQKRNNKCGISNGSKYKVFGGWRSMPGEWPWQVQIEREGAHHCGGALIHPNWVVTAAHCTFFFQDLPIEKWRIRAGKTQTNMTEPHEQNVRVKKLIDHPGFTLFTKYHDIALIQLEDPMYFDYKFVSPICLPNPQESFDDHV-CTLSGYGKTES--SGEGASTYLLEVNLPIISADTCQEKHCNSN-SIYEENLCAGFKEGKRDACTGDSGGPIVCEKLSVNGFKQFVLAGVVSYGSGCGGKDTPGVYTRISSYLDWIE 1046
            ++ R  SH   K L    K Q+    CG   G + ++ GG  +  G WPWQV I+++  H CGG LI  NWV++AAHC  F     +  + + AG+ Q +   PHE   ++K+++   G+T      DIAL+ L  P+ +  + + PICLP+    F +   CT++G+G      S +G  T L +V +PII    CQE        I  + +CAG+KEG +D+C GDSGGP+VC  LS +G  ++V AG+VS+G GC   + PGVY R+S++  +I+
Sbjct:   24 RLSRCFSHALSKGLWTTSKAQE----CG--RGVQSRIVGGTDASEGHWPWQVDIQKKSEHICGGTLISENWVLSAAHC--FPNPSDVSPYNVYAGRLQLHGWNPHEMERQIKQIVVPFGYTDAELGEDIALVMLSSPVTWS-EVIQPICLPDSDMQFAEGTQCTITGWGDIRDGVSLQGVGT-LQQVQVPIIGQSACQEMFTGEKFGIRHDMICAGYKEGGKDSCQGDSGGPLVC--LSESG--KWVQAGIVSFGLGCAQPNRPGVYARVSAFSSFIQ 287
[Close]
BLAST of Serine protease vs. Ensembl Cavefish
Match: zgc:92313 (serine protease 33-like [Source:NCBI gene;Acc:111192381])

HSP 1 Score: 171.014 bits (432), Expect = 8.398e-50
Identity = 97/257 (37.74%), Postives = 149/257 (57.98%), Query Frame = 3 
Query:  288 KRNNKCGISNGSKYKVFGGWRSMPGEWPWQVQIEREGAHHCGGALIHPNWVVTAAHCTFFFQDLPIEKWRIRAGKTQTNMTEPHEQNVRVKKLIDHPGFTLFTKYHDIALIQLEDPMYFDYKFVSPICLPNPQESFDDHV-CTLSGYGKTES--SGEGASTYLLEVNLPIISADTCQEKHCNSN-SIYEENLCAGFKEGKRDACTGDSGGPIVCEKLSVNGFKQFVLAGVVSYGSGCGGKDTPGVYTRISSYLDWIE 1046
             +  +CG   G + ++ GG  +  G WPWQV I+++  H CGG LI  NWV++AAHC  F     +  + + AG+ Q +   PHE   ++K+++   G+T      DIAL+ L  P+ +  + + PICLP+    F +   CT++G+G      S +G  T L +V +PII    CQE        I  + +CAG+KEG +D+C GDSGGP+VC  LS +G  ++V AG+VS+G GC   + PGVY R+S++  +I+
Sbjct:   24 SKAQECG--RGVQSRIVGGTDASEGHWPWQVDIQKKSEHICGGTLISENWVLSAAHC--FPNPSDVSPYNVYAGRLQLHGWNPHEMERQIKQIVVPFGYTDAELGEDIALVMLSSPVTWS-EVIQPICLPDSDMQFAEGTQCTITGWGDIRDGVSLQGVGT-LQQVQVPIIGQSACQEMFTGEKFGIRHDMICAGYKEGGKDSCQGDSGGPLVC--LSESG--KWVQAGIVSFGLGCAQPNRPGVYARVSAFSSFIQ 270
[Close]
BLAST of Serine protease vs. Ensembl Cavefish
Match: tmprss3a (transmembrane serine protease 3 [Source:NCBI gene;Acc:103026237])

HSP 1 Score: 176.022 bits (445), Expect = 2.783e-49
Identity = 96/252 (38.10%), Postives = 144/252 (57.14%), Query Frame = 3 
Query:  300 KCGISNGSKYKVFGGWRSMPGEWPWQVQIEREGAHHCGGALIHPNWVVTAAHCTFFFQDLPIEKWRIRAGKTQTNMTEPHEQNVRVKKLIDHPGFTLFTKYHDIALIQLEDPMYFDYKFVSPICLPNPQESFDD-HVCTLSGYGKTESSGEGASTYLLEVNLPIISADTCQEKHCNSNSIYEENLCAGFKEGKRDACTGDSGGPIVCEKLSVNGFKQFVLAGVVSYGSGCGGKDTPGVYTRISSYLDWIEYE 1052
            +CG       ++ GG  S+ G++PWQV ++ +  H CGG+++   W++TAAHC + F   P + W +  G T+  ++    + + V+K+I H  +      +DIAL++L +P+ F+   V PICLPN  E F+D  +C +SG+G TE  GE AS  L    +P+ISA  C +       I    +CAG+ EG  D+C GDSGGP+ CE  SV     + L G  S+G GC  ++ PGVYTRI+  L WI  +
Sbjct:  305 ECGSRPQFSTRIVGGNLSLEGQFPWQVSLQFQNEHLCGGSIVATRWILTAAHCVYGFA-FP-QVWTVLVGLTEQPVSVSGAKYLSVEKIIYHARYRPKGLDYDIALLKLVEPLAFN-GLVEPICLPNFGEEFEDGKMCWISGWGATEDGGE-ASVSLHSARVPLISAKACSQPEVYQGYISPGMICAGYLEGGTDSCQGDSGGPLACEDSSV-----WKLVGATSWGQGCAERNKPGVYTRITQALTWIHQQ 547
[Close]
BLAST of Serine protease vs. Ensembl Cavefish
Match: ENSAMXT00000039451.1 (trypsin-like [Source:NCBI gene;Acc:111192060])

HSP 1 Score: 167.933 bits (424), Expect = 1.450e-48
Identity = 89/245 (36.33%), Postives = 133/245 (54.29%), Query Frame = 3 
Query:  330 KVFGGWRSMPGEWPWQVQIEREGAHHCGGALIHPNWVVTAAHCTFFFQDLPIEKWRIRAGKTQTNMTEPHEQNVRVKKLIDHPGFTLFTKYHDIALIQLEDPMYFDYKFVSPICLPNPQESFDDHVCT-LSGYGKTESSGEGAS-TYLLEVNLPIISADTCQEKHCNSNSIYEENLCAGFKEGKRDACTGDSGGPIVCEKLSVNGFKQFVLAGVVSYGSGCGGKDTPGVYTRISSYLDWIEYETG 1058
            K+ GG  ++ G WPWQV I+  G+H CGG+LI+ NW+++AAHC    Q   +   R+  GK     +E +   + V ++I+HP +   T  +DIAL+QL   + F   ++ P+CL     +        ++G+G   S         L EV LPI+S   C   +  S SI    +CAG  +G +D+C GDSGGP+V ++    G+ Q   AG+VS+G GC     PGVY R+S Y +WI  + G
Sbjct:   36 KIVGGNTAVSGSWPWQVSIQSLGSHFCGGSLINNNWILSAAHCFQSSQTSTLAFLRVSLGKQSLQTSELNSLTITVAQIINHPSYVSSTHDNDIALLQLSSSVTFS-DYIQPVCLAAAGSTLGSGTLVWVTGWGDISSDVSLPDPQNLQEVELPIVSNTACTSAY-GSGSITSNMMCAGLSQGGKDSCQGDSGGPLVIKQ--STGWTQ---AGIVSFGYGCALPKIPGVYARVSEYQNWINSQIG 273
[Close]
BLAST of Serine protease vs. Ensembl Cavefish
Match: ENSAMXT00000033802.1 (pep primary_assembly:Astyanax_mexicanus-2.0:3:21891941:21894733:1 gene:ENSAMXG00000030254.1 transcript:ENSAMXT00000033802.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 166.777 bits (421), Expect = 2.446e-48
Identity = 109/330 (33.03%), Postives = 168/330 (50.91%), Query Frame = 3 
Query:  111 YKDETPICYRKYDGVCVLKSDPCPFKGEFVEVKPE-ENEKICREESH--RCCKPLNKNEKPQKRNNKCGISNGSKYKVFGGWRSMPGEWPWQV--QIEREGAHHCGGALIHPNWVVTAAHCTFFFQDLPI-----EKWRIRAGKTQTNMTEPHEQNVRVKKLIDHPGFTLFTKYHDIALIQLEDPMYFDYKFVSPICLPNPQESFDD-HVCTLSGYGKTESSGEGASTYLLEVNLPIISADTCQEKHCNSNSIYEENLCAGFKEGKRDACTGDSGGPIVCEKLSVNGFKQFVLAGVVSYGSGCGGKDTPGVYTRISSYLDWIEYETGIEV 1067
            +K  +P  Y+  +G CV K            V PE +  K C++ S   RCC       +P+KR            K+ GG  +  G WPWQV  Q+ER G H CG +L+   W+++AAHC   FQD          WR   G    N         ++++++ H  +  FT  +DIAL++L  P++F+   V P+C+P P  +F     C ++G+G      E  +T L E  + IIS  TC + +   +++    +CAG  +G  DAC GDSGGP+VC +      +++ LAG+VS+G GC  ++ PGVYT++  + DWI  +T  +V
Sbjct:    4 HKGCSPTSYKCANGKCVNK------------VNPECDGIKDCKDGSDEMRCC-----GTRPRKRA-----------KIVGGTDAQAGSWPWQVSLQMERYG-HVCGASLVGTRWLLSAAHC---FQDSDAIYSDARAWRAFLGMRVMNTASNAAATRQIRRIVQHAQYDQFTSDYDIALLELSAPVFFN-DLVQPVCVPAPSHAFTSGTTCFVTGWGVLTE--EELATLLQEATVSIISHKTCNKMY--DDAVTPRMICAGNIQGGVDACQGDSGGPLVCLERG----RRWFLAGIVSWGEGCARQNRPGVYTQVIKFTDWIHQQTKGQV 292
[Close]
BLAST of Serine protease vs. Ensembl Sea Lamprey
Match: tmprss3a (transmembrane serine protease 3a [Source:ZFIN;Acc:ZDB-GENE-070912-70])

HSP 1 Score: 171.785 bits (434), Expect = 6.633e-50
Identity = 97/251 (38.65%), Postives = 141/251 (56.18%), Query Frame = 3 
Query:  300 KCGISNGSKYKVFGGWRSMPGEWPWQVQIEREGAHHCGGALIHPNWVVTAAHCTFFFQDLPIEKWRIRAGKTQTNMTEPHEQNVRVKKLIDHPGFTLFTKY-HDIALIQLEDPMYFDYKFVSPICLPNPQESFDDHV-CTLSGYGKTESSGEGASTYLLEVNLPIISADTCQEKHCNSNSIYEENLCAGFKEGKRDACTGDSGGPIVCEKLSVNGFKQFVLAGVVSYGSGCGGKDTPGVYTRISSYLDWIE 1046
             CG S  S  ++ GG  +  G WPWQV ++  G H CGG L+ P WV++AAHC  F   L  + W +      T++T     ++   K+I +  +   T   +DIAL++L  P+      + P CLPN Q  F   + C ++G+G T+ S   AST L EV +PI+S +TC   +  +  I    +CAGF +G +DAC GDSGGP+VC+     G   FV+ G  S+G GC   + PGVY+R+++YLDWI 
Sbjct:  112 ACGSSIKSTSRIVGGQDAQLGSWPWQVSLQFNGQHTCGGTLLTPTWVLSAAHC--FQGYLGPDMWNV------TDLTSNLAGSI--SKIITNSQYVDNTNNDYDIALVKLSKPLSMS-NTIGPACLPNYQTDFQVGMNCWITGWGATKVSAGPASTTLQEVMVPILSTETCNAANSYNGQITSRMVCAGFMQGGQDACQGDSGGPLVCQT----GTTWFVV-GATSFGEGCALTNFPGVYSRVTAYLDWIH 346
[Close]
BLAST of Serine protease vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006128.1 (pep scaffold:Pmarinus_7.0:GL484169:9759:12797:-1 gene:ENSPMAG00000005545.1 transcript:ENSPMAT00000006128.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 160.999 bits (406), Expect = 2.582e-47
Identity = 91/252 (36.11%), Postives = 132/252 (52.38%), Query Frame = 3 
Query:  303 CGISN--GSKYKVFGGWRSMPGEWPWQVQIEREGAHHCGGALIHPNWVVTAAHCTFFFQDLPIEKWRIRAGKTQTNMTEPHEQNVRVKKLIDHPGFTLFTKYHDIALIQLEDPMYFDYKFVSPICLPNPQESFDD--HVCTLSGYGKTESSGEGASTYLLEVNLPIISADTCQEKHCNSNSIYEENLCAGFKEGKRDACTGDSGGPIVCEKLSVNGFKQFVLAGVVSYGSGCGGKDTPGVYTRISSYLDWIE 1046
            CG+ N  G + ++ GG  +  G+WPWQ  +   G+H CG +LI   W+V AAHC  F     + +W++  G T       +   V V ++I H  F + T  +DIAL++L DP+ F+++ VSPICLP     F      C +SG+G+T  +  G    LLE  + I S + C     N N I    +C G   G   +C GDSGGP+ C+       K + L+GV S+G GC     P VYT+ S +L WI+
Sbjct:    4 CGVQNSAGGRDRIVGGTPATSGKWPWQASLRNYGSHVCGASLISERWLVAAAHC--FMYSSNVYEWQVYLGITYI-YDSANAVIVNVAEIITHERFNISTIDYDIALVRLSDPVSFNHR-VSPICLPPSTSHFPQPGKTCFISGWGRTSLAESGIHYDLLEAPMQIFSHEACSSNLMNGNFITTRMICIGHPAGAISSCQGDSGGPLACQGTD----KAWYLSGVTSWGFGCALPMKPVVYTKTSKFLPWIK 247
[Close]
BLAST of Serine protease vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001315.1 (pep scaffold:Pmarinus_7.0:GL479305:249343:254401:-1 gene:ENSPMAG00000001180.1 transcript:ENSPMAT00000001315.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 157.147 bits (396), Expect = 6.093e-45
Identity = 87/246 (35.37%), Postives = 135/246 (54.88%), Query Frame = 3 
Query:  324 KYKVFGGWRSMPGEWPWQVQIER--EGAHHCGGALIHPNWVVTAAHCTFF--FQDLPIEKWRIRAGKTQTNMTEPHEQNVRVKKLIDHPGFTLFTKYHDIALIQLEDPMYFDYKFVSPICLPNPQESF-DDHVCTLSGYGKTESSGEGASTYLLEVNLPIISADTCQEKHCNSNSIYEENLCAGFKEGKRDAC-TGDSGGPIVCEKLSVNGFKQFVLAGVVSYGSGCGGKDTPGVYTRISSYLDWI 1043
            K ++ GG  ++ G WPWQ  +       HHCGG+LIHP WV+TAAHC +    +   +  W +  GK   +   P EQ+  +++++ H  +      +DIAL++L+ P+    + V  +C+P    +F    +C +SG+G    +    S  + EV LP+IS   C   +   +      LCAG+ +G +DAC  GDSGGP+VCE         + LAG+VS+G GCG  + PGVYTR++++  WI
Sbjct:   86 KSRIVGGESALAGAWPWQASLWSGLTKNHHCGGSLIHPKWVLTAAHCVYGKNCRVEALSDWTLFFGKLLLDKEGPMEQHRSIRQIVVHRQYVSSENDYDIALLELDSPVNLTEQ-VQTVCMPAASHAFLPGQMCWVSGWGTVIGNEFSLSNNMQEVQLPLISQSDCIGSY---DHATPRMLCAGYPDGGKDACQQGDSGGPLVCEDRG-----SWFLAGLVSWGVGCGLVNKPGVYTRVTAFTKWI 322
[Close]
BLAST of Serine protease vs. Ensembl Sea Lamprey
Match: f10 (coagulation factor X [Source:ZFIN;Acc:ZDB-GENE-021206-9])

HSP 1 Score: 147.132 bits (370), Expect = 5.272e-40
Identity = 110/330 (33.33%), Postives = 162/330 (49.09%), Query Frame = 3 
Query:  105 LGYKDETPIC-----YRKYDG--VCV-LKSDPC-PFKGEFVEVKPEENEKICREESHRCCKPLNKNEKPQKRNNKCGISNGSKYKVFGGWRSMP-GEWPWQVQIEREGAHHCGGALIHPNWVVTAAHCTFFFQDLPIEKWRIRAGKTQTNMTEPHEQNVRVKKLIDHPGFTLFTKYHDIALIQLEDPMYFDYKFVSPICLPNPQESFDDHVCT-----LSGYGKTESSGEGASTYLLEVNLPIISADTCQEKHCNSNSIYEENL-CAGFKEGKRDACTGDSGGPIVCEKLSVNGFKQFVLA-GVVSYGSGCGGKDTPGVYTRISSYLDWI 1043
            L  +++ P+C     YR  D    C  +++ PC     E +  K EEN +     SH      + N K Q  N           K   G    P G+ PWQ  ++ E   +CGG +++  W++TAAHC      LP++ W +  G+    +TE  EQ+V +K ++ H  +   T  +DIAL+QLE P+ F  + V P CL  P+  F D V       +SG+G     G  A T L    +P +    C+E   +S+S+  +N+ CAG+ +G +DAC  DSGGP       V  FK    A G++S+G GC  K   GVYTR+S YL W+
Sbjct:  140 LDQENKAPVCTCVKGYRLQDDGHTCEPVEAFPCGRLHPEEIRAKREENRQDEFFTSHS-----DDNLKAQPHNTSSIKEEREDVKTIAGGMDCPRGDCPWQALVKLENNLYCGGTILNLEWILTAAHC------LPLKPWNVVVGEHNLGVTESSEQHVPIKNIVVHSRYDPITFDNDIALLQLERPLNFS-RLVLPACL--PERDFADKVLVEEQSRISGWGSLHHRGIKA-TVLQIAEVPFVDTLRCKE---SSSSLVTKNMFCAGYSDGTKDACQHDSGGP------HVTLFKDTWFATGIISWGEGCARKGKYGVYTRVSRYLLWM 445
[Close]
BLAST of Serine protease vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002258.1 (pep scaffold:Pmarinus_7.0:GL487751:502724:507790:1 gene:ENSPMAG00000002029.1 transcript:ENSPMAT00000002258.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 142.124 bits (357), Expect = 5.663e-40
Identity = 86/240 (35.83%), Postives = 131/240 (54.58%), Query Frame = 3 
Query:  330 KVFGGWRSMPGEWPWQVQIERE-GAHHCGGALIHPNWVVTAAHCTFFFQDLPIEKWRIRAGKTQTNMTEPHEQNVRVKKLIDHPGFTLFTKYHDIALIQLEDPMYFDYKFVSPICLPNPQESFDDHV-CTLSGYGKTESSGEGASTYLLEVNLPIISADTCQEKHCNSNSIYEENLCAGFKEGKRDACTGDSGGPIVCEKLSVNGFKQFVLAGVVSYGSGCGGKDTPGVYTRISSYLDWI 1043
            +V  G  ++PG WPWQV ++ E G H CGG++I P WV+TAAHC     D      RI  G+   +    + Q + V+K I HP +   T  +DI L++L++P +F    VSPICLP   ++F       ++G+G T  +    S+ L +  LP+IS + C  K    + I +  +CAG        C GDSGGP+  +K  +     +VLAG+ S+G+       P VYTR+++++DWI
Sbjct:   33 RVINGEEAVPGSWPWQVSLQYEDGFHFCGGSIIDPYWVITAAHC-----DFKPANHRIIVGEHDKSSNVENIQILYVEKAITHPLYDANTINNDILLLKLKEPAFFG-DTVSPICLPRATDTFSPGTHAAVTGWGVTRWNANYGSSTLQQTVLPLISTEDC--KKWWGSYIMDPMICAG--ANGHSTCMGDSGGPLTVQKDGM-----WVLAGLTSWGNSRCDTSVPVVYTRVTTFVDWI 257
[Close]
BLAST of Serine protease vs. Ensembl Nematostella
Match: EDO47761 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RKX8])

HSP 1 Score: 166.007 bits (419), Expect = 3.963e-49
Identity = 90/244 (36.89%), Postives = 132/244 (54.10%), Query Frame = 3 
Query:  330 KVFGGWRSMPGEWPWQVQI-----EREGAHHCGGALIHPNWVVTAAHCTFFFQDLPIEKWRIRAGKTQTNMTEPHEQNVRVKKLIDHPGFTLFTKYHDIALIQLEDPMYFDYKFVSPICLPNPQESFDDHV-CTLSGYGKTESSGEGASTYLLEVNLPIISADTCQEKHCNSNSIYEENLCAGFKEGKRDACTGDSGGPIVCEKLSVNGFKQFVLAGVVSYGSGCGGKDTPGVYTRISSYLDWI 1043
            ++ GG  + PG WPWQV +       +GA  CGG+LI P WV+TAAHC    +D    ++ +R G+   N  E  EQ+  ++K   HP +   T  +D+ALI+L+ P   + K V+ ICLP   + F     CT+SG+G  +      S  L++  +P++S D C  +    + I E  LCAG ++G  D+C GDSGGP VC   +    +Q+ L GV S+G GC      G+Y  +  YL WI
Sbjct:    1 RIVGGVVAKPGAWPWQVALIWAKGHDKGAQFCGGSLIDPEWVLTAAHCFEITKDK--SQYMLRLGEHNFNEDEGTEQDFYIEKYYIHPKYDEKTTDNDMALIKLDRPATLN-KRVNTICLPEADDEFKPGTKCTISGWGALQEGAGSTSKVLMQAKVPLVSRDQCSHQQSYGDRITENMLCAGMRQGGVDSCQGDSGGPFVC--TNPENPRQWTLVGVTSWGKGCARALKYGIYANVRRYLHWI 239
[Close]
BLAST of Serine protease vs. Ensembl Nematostella
Match: EDO41035 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S5M4])

HSP 1 Score: 165.236 bits (417), Expect = 1.012e-48
Identity = 93/252 (36.90%), Postives = 136/252 (53.97%), Query Frame = 3 
Query:  303 CGISNGSKYKVFGGWRSMPGEWPWQVQIERE-GAHHCGGALIHPNWVVTAAHCTFFFQDLPIEKWRIRAGKTQTNMTEPHEQNVRVKKLIDHPGFTLFTKYHDIALIQLEDPMYFDYKFVSPICLPNPQES-FDDHVCTLSGYGKTESSGEGASTYLLEVNLPIISADTCQEKHCNSNSIYEENLCAGFKEGKRDACTGDSGGPIVCEKLSVNGFKQFVLAGVVSYGSGCGGKDTPGVYTRISSYLDWIEYE 1052
            CG+S+ S  ++ GG  + PG+WPWQ Q+    G  +CGG+LIH NWV+TAAHC       P E        ++        Q+++V  +I H  +   T Y+DIAL++L  P   + K V  +CLP  + S  D   C ++G+G T SSG      L E ++P++S   C++ + + N I++  LCAG   G  D C GDSGGP+VCE        +FVL G  S+G GC  K   GVY  +   L W++ +
Sbjct:    4 CGVSS-STSRIVGGAAANPGDWPWQAQLRTTTGFPYCGGSLIHSNWVLTAAHC--ISSKRPAEVVVRLGAHSRLGSLTTDMQDIKVSAIITHSNYNSRTMYNDIALLKLATPAQTNSK-VGFVCLPETEASPSDGTTCWITGWG-TLSSGGSPPDILQEASVPVVSRARCEQAYTDPNQIHDSMLCAGLDNGGVDTCQGDSGGPLVCES-----GGKFVLHGATSWGYGCAAKGKFGVYANVKYLLTWVKTQ 245
[Close]
BLAST of Serine protease vs. Ensembl Nematostella
Match: EDO39623 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S9K4])

HSP 1 Score: 162.925 bits (411), Expect = 6.564e-48
Identity = 92/243 (37.86%), Postives = 144/243 (59.26%), Query Frame = 3 
Query:  333 VFGGWRSMPGEWPWQVQIE-REGAHHCGGALIHPNWVVTAAHCTFFFQDLPIEKWRIRAGKTQTNMTEPHEQNVRVKKLIDHPGFTLFTKY-HDIALIQLEDPMYFDYKFVSPICLPNPQESFDDHV-CTLSGYGKTESSGEGASTYLLEVNLPIISADTCQEKHCNSNSIYEENLCAGFKEGKRDACTGDSGGPIVCEKLSVNGFKQFVLAGVVSYGSGCGGKDTPGVYTRISSYLDWIEYE 1052
            + GG ++ PG+WPWQVQ+  REG  +CGG LIHP W++TA HC      LP +   IR G  +   +   EQ++ V ++I HP ++   +Y +DIAL++L  P   + KF++ +CLP+  +   +H  C ++G+G+  S G  A   L + ++PI+S   C+  +     +++  LCAG+ +G  D+C GDSGGP+VCE        +F L GV S+G GCG +   GVY++++  L WI  E
Sbjct:    1 MVGGTQAKPGDWPWQVQLRSREGYPYCGGTLIHPQWILTATHC--LKNKLP-QDIVIRLGAQRRLESVGEEQDINVTRIIKHPSYSSPVRYAYDIALLKLRKPAELN-KFINLVCLPHGMQIPAEHTKCWITGWGRL-SPGGWAPINLRQASVPIVSRARCEVTY--PKRLHDSMLCAGYDQGGIDSCQGDSGGPMVCES-----GGRFFLHGVTSWGVGCGFRGNFGVYSKVTHSLGWILKE 231
[Close]
BLAST of Serine protease vs. Ensembl Nematostella
Match: EDO42420 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S1T0])

HSP 1 Score: 157.918 bits (398), Expect = 7.427e-46
Identity = 93/257 (36.19%), Postives = 137/257 (53.31%), Query Frame = 3 
Query:  294 NNKCGISNGSKYKVFGGWRSMPGEWPWQVQIERE-GAHHCGGALIHPNWVVTAAHCTFFFQDLPIEKWRIRAGKTQTNMTEPHEQNVRVKKLIDHPGFTLFTKY-HDIALIQLEDPMYFDYKFVSPICLPN--PQESFDDHVCTLSGYGKTESSGEGASTYLLEVNLPIISADTCQEKHCNSNSIYEENLCAGFKEGKRDACTGDSGGPIVCEKLSVNGFKQFVLAGVVSYGSGCGGKDTPGVYTRISSYLDWIEYE 1052
            +  CG+S+ ++  + GG  +  G WPWQ Q+    G  +CGG LIHP WV+TA HC    +     +  IR G  +      +EQ+ RV +L+ HP +     Y +DIAL++L+ P   D ++V+  CLP+  P+    D  C ++G+GK  S G  A   L +  +P++    C + +     I+E  LCAG   G  DAC GDSGGP+VCE        +F + G  S+G+GC      GVY R+   LDWI+ E
Sbjct:    7 SGSCGVSHHAR--IVGGTTAQQGGWPWQAQLRTSTGYPYCGGTLIHPEWVLTATHC---LKGETASRVHIRLGAHRRTKGSGNEQDFRVIRLVTHPNYHRPVGYANDIALLKLDRPAKLD-RYVNFACLPDQVPEPKEGDR-CYITGWGKLSSHGS-APDILQQATVPVVGRARCMKAY--RGQIHESMLCAGLDAGGVDACQGDSGGPMVCENAG-----RFYIQGATSWGNGCAAPGKFGVYARVKYVLDWIKSE 248
[Close]
BLAST of Serine protease vs. Ensembl Nematostella
Match: EDO34064 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SQE8])

HSP 1 Score: 156.377 bits (394), Expect = 2.537e-45
Identity = 93/245 (37.96%), Postives = 139/245 (56.73%), Query Frame = 3 
Query:  333 VFGGWRSMPGEWPWQVQIEREGA-HHCGGALIHPNWVVTAAHC--TFFFQDLPIEKWRIRAGKTQTNMTEPHEQNVRVKKLIDHPGFTL----FTKYHDIALIQLEDPMYFDYKFVSPICLPNPQESFDDHV-CTLSGYGKTESSGEGASTYLLEVNLPIISADTCQEKHCNSNSIYEENLCAGFKEGKRDACTGDSGGPIVCEKLSVNGFKQFVLAGVVSYGSGCGGKDTPGVYTRISSYLDWI 1043
            + GG  + P  WPWQV +   G  H+CGG+LI   WVVT+ HC     +  +P+  +  R G+ + + TE  E+ ++ +KL  HP + L    +T  +DIAL++L+ P  F YK V  +CLP    S  D   C ++G+G+T  + EG S  L E  + ++S DTC   +  S  I E  +CAG+  G  D+C GDSGGP+VC +    G   FVL G+VS+G GC   +  GVY +++S + +I
Sbjct:    2 IVGGREASPNSWPWQVDLVVNGTRHNCGGSLIDKQWVVTSGHCFDQRPYAYIPLSYYEFRLGEHRESTTEGWEEIIKGEKLFIHPKYKLGGLDYTGDYDIALVKLKRPAVF-YKRVHSVCLPEKSWSPPDGAGCYVTGWGRTAEN-EGYSDVLREAQVRLVSRDTCNASY--SGIINERYICAGYPGGGVDSCGGDSGGPLVCPR----GDGSFVLTGIVSWGKGCARPNYVGVYLQVTSMMSFI 238
[Close]
BLAST of Serine protease vs. Ensembl Medaka
Match: ENSORLT00000040448.1 (pep primary_assembly:ASM223467v1:8:2449519:2451077:1 gene:ENSORLG00000025659.1 transcript:ENSORLT00000040448.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 167.548 bits (423), Expect = 8.248e-49
Identity = 90/251 (35.86%), Postives = 145/251 (57.77%), Query Frame = 3 
Query:  303 CGISNGSKYKVFGGWRSMPGEWPWQVQIEREGAHHCGGALIHPNWVVTAAHCTFFFQDLPIEKWRIRAGKTQTNMTEPHEQNVRVKKLIDHPGFTLFTKYHDIALIQLEDPMYFDYKFVSPICLPNPQESFDDHVCT-LSGYGKTESSGEGASTYLLEVNLPIISADTCQEKHCNSNSIYEENLCAGFKEGKRDACTGDSGGPIVCEKLSVNGFKQFVLAGVVSYGSGCGGKDTPGVYTRISSYLDWIEYE 1052
            CG++N +  ++ GG  ++PG WPWQV ++    H CGG+LI+  WV+TAAHC   F            G      + P+  +  +K +I HP +   T+ +DIAL+QL  P+ F+  +++P+CLP+   +F   V T ++G+G   + G+      LE+ +PI+    C+  +  ++SI +  +CAG   G +D+C GDSGGP+V ++       +++ AGVVS+G+GC   D PGVYTR+S Y  WI  +
Sbjct:   18 CGLANLNS-RIVGGQNALPGSWPWQVSLQSS-YHFCGGSLINNQWVLTAAHC---FPSRSASGVNAVLGLQSLQGSNPNRVSRTIKTVIVHPNYNSGTQNNDIALLQLSSPVTFN-NYITPVCLPSTGSTFYSGVKTWVTGWGDIGNGGQ------LEIQIPIVGNRRCKCSY-GASSITDNMMCAGLLAGGKDSCQGDSGGPLVIKQ-----NNRWIQAGVVSFGNGCAEPDFPGVYTRVSRYQTWINTQ 250
[Close]
BLAST of Serine protease vs. Ensembl Medaka
Match: tmprss3a (transmembrane serine protease 3 [Source:NCBI gene;Acc:101164532])

HSP 1 Score: 170.629 bits (431), Expect = 4.069e-48
Identity = 95/260 (36.54%), Postives = 139/260 (53.46%), Query Frame = 3 
Query:  300 KCGISNGSKYKVFGGWRSMPGEWPWQVQIEREGAHHCGGALIHPNWVVTAAHCTFFFQDLPIEKWRIRAGKTQTNMTEPHEQNVRVKKLIDHPGFTLFTKYHDIALIQLEDPMYFDYKFVSPICLPNPQESF-DDHVCTLSGYGKTESSGEGASTYLLEVNLPIISADTCQEKHCNSNSIYEENLCAGFKEGKRDACTGDSGGPIVCEKLSVNGFKQFVLAGVVSYGSGCGGKDTPGVYTRISSYLDWIEYETGIEVSTG 1076
            +CG     + +V GG  S+PG++PWQ  +   G H CGG++I P W+VTAAHC       PI                   Q++ V+K++ H  +   +  +DIAL++L+ P+ F+   V PICLPN  E F +D  C +SG+G TE  GE +S  L    +P+IS  TC +    +  I    +CAG+ EG  D+C GDSGGP+ C   S      + L G  S+G GC  ++ PGVYTR+++ L WI  +  +    G
Sbjct:  177 ECGSRPRYQTRVVGGNLSLPGQFPWQASLHFRGEHMCGGSVISPLWIVTAAHC-------PIHA----------------AQSLAVRKIVYHARYRSRSLDYDIALMRLDQPLTFN-GLVEPICLPNHGEDFQEDTKCWISGWGATEEDGE-SSVVLRAAVVPLISTRTCNQPEVYAGHISSWMICAGYLEGGVDSCQGDSGGPLACHDPSA-----WKLVGATSWGEGCAARNRPGVYTRVTTALSWIRKQMEVSAEGG 406
[Close]
BLAST of Serine protease vs. Ensembl Medaka
Match: TMPRSS6 (transmembrane serine protease 6 [Source:NCBI gene;Acc:101162577])

HSP 1 Score: 172.94 bits (437), Expect = 3.451e-47
Identity = 96/250 (38.40%), Postives = 142/250 (56.80%), Query Frame = 3 
Query:  303 CGISNGSKYKVFGGWRSMPGEWPWQVQIEREGAHHCGGALIHPNWVVTAAHCTFFFQDLPIEKWRIRAGKTQTNMTEPHEQNVRVKKLIDHPGFTLFTKYHDIALIQLEDPM-YFDYKFVSPICLPNPQESFD-DHVCTLSGYGKTESSGEGASTYLLEVNLPIISADTCQEKHCNSNSIYEENLCAGFKEGKRDACTGDSGGPIVCEKLSVNGFKQFVLAGVVSYGSGCGGKDTPGVYTRISSYLDWIE 1046
            CG+   S  ++ GG  +  GEWPWQ  ++  G H CGGALI   WVV+AAHC +  +      W +  GK   N + P E+  RV+ +  H  +   ++ +D+AL++L+ P      +   P CLP P    + D +C ++G+G     G GAS  L +V++ ++S + C   +   + I    LCAG++ GK+D+C GDSGGP+VC++ S   F    LAGVVS+G GCG  D  GVYTRI+   DWI+
Sbjct:  544 CGLRQFSS-RIIGGKDASEGEWPWQASLQVRGTHICGGALISSQWVVSAAHCFYDDRLYSPTMWTVYLGKLFLNRSSPTEEVARVQHIHLHQYYDDESQDYDLALLKLDRPASALLAEHARPACLPPPTHQLEPDLLCWVTGWGALREGG-GASNVLQKVDVRLVSEEDCVRSY--GHLISPRMLCAGYRNGKKDSCQGDSGGPLVCQEASGRWF----LAGVVSWGRGCGRPDNYGVYTRITRLTDWIK 785
[Close]
BLAST of Serine protease vs. Ensembl Medaka
Match: TMPRSS6 (transmembrane serine protease 6 [Source:NCBI gene;Acc:101162577])

HSP 1 Score: 172.94 bits (437), Expect = 3.453e-47
Identity = 96/250 (38.40%), Postives = 142/250 (56.80%), Query Frame = 3 
Query:  303 CGISNGSKYKVFGGWRSMPGEWPWQVQIEREGAHHCGGALIHPNWVVTAAHCTFFFQDLPIEKWRIRAGKTQTNMTEPHEQNVRVKKLIDHPGFTLFTKYHDIALIQLEDPM-YFDYKFVSPICLPNPQESFD-DHVCTLSGYGKTESSGEGASTYLLEVNLPIISADTCQEKHCNSNSIYEENLCAGFKEGKRDACTGDSGGPIVCEKLSVNGFKQFVLAGVVSYGSGCGGKDTPGVYTRISSYLDWIE 1046
            CG+   S  ++ GG  +  GEWPWQ  ++  G H CGGALI   WVV+AAHC +  +      W +  GK   N + P E+  RV+ +  H  +   ++ +D+AL++L+ P      +   P CLP P    + D +C ++G+G     G GAS  L +V++ ++S + C   +   + I    LCAG++ GK+D+C GDSGGP+VC++ S   F    LAGVVS+G GCG  D  GVYTRI+   DWI+
Sbjct:  558 CGLRQFSS-RIIGGKDASEGEWPWQASLQVRGTHICGGALISSQWVVSAAHCFYDDRLYSPTMWTVYLGKLFLNRSSPTEEVARVQHIHLHQYYDDESQDYDLALLKLDRPASALLAEHARPACLPPPTHQLEPDLLCWVTGWGALREGG-GASNVLQKVDVRLVSEEDCVRSY--GHLISPRMLCAGYRNGKKDSCQGDSGGPLVCQEASGRWF----LAGVVSWGRGCGRPDNYGVYTRITRLTDWIK 799
[Close]
BLAST of Serine protease vs. Ensembl Medaka
Match: ENSORLT00000029619.1 (pep primary_assembly:ASM223467v1:8:2446843:2452083:1 gene:ENSORLG00000025659.1 transcript:ENSORLT00000029619.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 164.081 bits (414), Expect = 6.367e-47
Identity = 98/282 (34.75%), Postives = 156/282 (55.32%), Query Frame = 3 
Query:  234 REESHRCCKPLNKNEKPQKRNNKCGISNGSKYKVFGGWRSMPGEWPWQVQIEREGAHHCGGALIHPNWVVTAAHC----TFFFQDLPIEKWRIRAGKTQTNMTEPHEQNVRVKKLIDHPGFTLFTKYHDIALIQLEDPMYFDYKFVSPICLPNPQESFDDHVCT-LSGYGKTESSGEGAST----YLLEVNLPIISADTCQEKHCNSNSIYEENLCAGFKEGKRDACTGDSGGPIVCEKLSVNGFKQFVLAGVVSYGSGCGGKDTPGVYTRISSYLDWIEYE 1052
            RE+   C K L      Q   + CG++N +  ++ GG  ++PG WPWQV ++    H CGG+LI+  WV+TAAH     T++F+ L                + P+  +  +K +I HP +   T+ +DIAL+QL  P+ F+  +++P+CLP+   +F   V T ++G+G     G G S      L E+ +PI+    C+  +  ++SI +  +CAG   G +D+C GDSGGP+V ++       +++ AGVVS+G+GC   D PGVYTR+S Y  WI  +
Sbjct:   16 REQICTCAKLLFWGRSAQT--DICGLANLNS-RIVGGQNALPGSWPWQVSLQSS-YHFCGGSLINNQWVLTAAHLNLTNTYYFKSL--------------QGSNPNRVSRTIKTVIVHPNYNSGTQNNDIALLQLSSPVTFN-NYITPVCLPSTGSTFYSGVKTWVTGWGDI---GNGVSLPAPETLQEIQIPIVGNRRCKCSY-GASSITDNMMCAGLLAGGKDSCQGDSGGPLVIKQ-----NNRWIQAGVVSFGNGCAEPDFPGVYTRVSRYQTWINTQ 269
[Close]
BLAST of Serine protease vs. Planmine SMEST
Match: SMESG000044335.1 (SMESG000044335.1)

HSP 1 Score: 766.918 bits (1979), Expect = 0.000e+0
Identity = 368/368 (100.00%), Postives = 368/368 (100.00%), Query Frame = 3 
Query:   48 MSRTKCLSFFLIIFYVSQVLGYKDETPICYRKYDGVCVLKSDPCPFKGEFVEVKPEENEKICREESHRCCKPLNKNEKPQKRNNKCGISNGSKYKVFGGWRSMPGEWPWQVQIEREGAHHCGGALIHPNWVVTAAHCTFFFQDLPIEKWRIRAGKTQTNMTEPHEQNVRVKKLIDHPGFTLFTKYHDIALIQLEDPMYFDYKFVSPICLPNPQESFDDHVCTLSGYGKTESSGEGASTYLLEVNLPIISADTCQEKHCNSNSIYEENLCAGFKEGKRDACTGDSGGPIVCEKLSVNGFKQFVLAGVVSYGSGCGGKDTPGVYTRISSYLDWIEYETGIEVSTGKFTMATQFTPEAVKRVVTDKCKPDK 1151
            MSRTKCLSFFLIIFYVSQVLGYKDETPICYRKYDGVCVLKSDPCPFKGEFVEVKPEENEKICREESHRCCKPLNKNEKPQKRNNKCGISNGSKYKVFGGWRSMPGEWPWQVQIEREGAHHCGGALIHPNWVVTAAHCTFFFQDLPIEKWRIRAGKTQTNMTEPHEQNVRVKKLIDHPGFTLFTKYHDIALIQLEDPMYFDYKFVSPICLPNPQESFDDHVCTLSGYGKTESSGEGASTYLLEVNLPIISADTCQEKHCNSNSIYEENLCAGFKEGKRDACTGDSGGPIVCEKLSVNGFKQFVLAGVVSYGSGCGGKDTPGVYTRISSYLDWIEYETGIEVSTGKFTMATQFTPEAVKRVVTDKCKPDK
Sbjct:    1 MSRTKCLSFFLIIFYVSQVLGYKDETPICYRKYDGVCVLKSDPCPFKGEFVEVKPEENEKICREESHRCCKPLNKNEKPQKRNNKCGISNGSKYKVFGGWRSMPGEWPWQVQIEREGAHHCGGALIHPNWVVTAAHCTFFFQDLPIEKWRIRAGKTQTNMTEPHEQNVRVKKLIDHPGFTLFTKYHDIALIQLEDPMYFDYKFVSPICLPNPQESFDDHVCTLSGYGKTESSGEGASTYLLEVNLPIISADTCQEKHCNSNSIYEENLCAGFKEGKRDACTGDSGGPIVCEKLSVNGFKQFVLAGVVSYGSGCGGKDTPGVYTRISSYLDWIEYETGIEVSTGKFTMATQFTPEAVKRVVTDKCKPDK 368
[Close]
BLAST of Serine protease vs. Planmine SMEST
Match: SMESG000002831.1 (SMESG000002831.1)

HSP 1 Score: 152.525 bits (384), Expect = 8.957e-42
Identity = 83/241 (34.44%), Postives = 132/241 (54.77%), Query Frame = 3 
Query:  321 SKYKVFGGWRSMPGEWPWQVQIEREGAHHCGGALIHPNWVVTAAHCTFFFQDLPIEKWRIRAGKTQTNMTEPHEQNVRVKKLIDHPGFTLFTKYHDIALIQLEDPMYFDYKFVSPICLPNPQESFDDHVCTLSGYGKTESSGEGASTYLLEVNLPIISADTCQEKHCNSNSIYEENLCAGFKEGKRDACTGDSGGPIVCEKLSVNGFKQFVLAGVVSYGSGCGGKDTPGVYTRISSYLDWI 1043
            ++ ++ GG  +  G WPWQV +       CGG++++  W+VTAAHC    +  P + W + AG+   N  + + Q  RV+K+I +  +      +DIA+++L   +  +  +V P+C+       D+  C ++G+G T   G G   YL +  +PII  +TCQ  +   NS+ +  +CAG++ G  D+C GDSGGP+VC   S     +F L G+ S+G GC     PGVYT  S YL W+
Sbjct:  192 TEMRIVGGIVAREGSWPWQVSLRNSDGVLCGGSIVNSKWIVTAAHC-VEGRSSP-QTWTVHAGRFTLNGNDRNLQVNRVEKVIKNENYRSENNENDIAMMKLSGILRLN-DYVEPVCIGTSVPR-DNAECYITGWGVTH--GTGGDGYLKQAKVPIIDQNTCQSWY--GNSLSDGMICAGYENGGTDSCQGDSGGPLVCRINS-----KFQLIGITSWGMGCAEPRQPGVYTAASKYLQWM 419
[Close]
BLAST of Serine protease vs. Planmine SMEST
Match: SMESG000022862.1 (SMESG000022862.1)

HSP 1 Score: 149.828 bits (377), Expect = 9.955e-42
Identity = 98/265 (36.98%), Postives = 137/265 (51.70%), Query Frame = 3 
Query:  330 KVFGGWRSMPGEWPWQVQIE-----------REGAHHCGGALIHPNWVVTAAHC-----TFFFQDLPIEKWRIRAGKTQTNMTEPHEQNVRVKKLIDHPG--FTLFTKYHDIALIQLEDPMYFDYKFVSPICLPNPQESF-DDHVCTLSGYGKTESSGEGASTYLLEVNLPIISADTCQEKHCNSNSIYEE--------NLCAGFKEGKRDACTGDSGGPIVCEKLSVNGFKQFVLAGVVSYGSGCGGKDTPGVYTRISSYLDWI 1043
            ++ GG  S   EWPW V +             +  H CGG LI  +W++TAAHC          + P  KW  R G+     TE H+ +  +K +  H     T      DIAL++LE P  F  +F+ P CLPNP E F ++ +CT  G+G T  +G  A      VNL ++S   C+  + N   I ++         LCAG   GK DAC  DSGGP++C+  S N    +++AG+VS+G  C G+  PG+YTR+SSYLDWI
Sbjct:   56 RIMGGKESREAEWPWLVSLSLWKSDVTGKKPEKSEHMCGGTLISRSWILTAAHCFEKKWENSLTNDP-SKWTARLGEHNLIKTEDHQMDHSIKAIFIHESRHLTRLETNDDIALVKLESPAQFT-RFIKPACLPNPDEKFHENTICTTIGWGFTSFNGSIAEIS-RHVNLELVSHQYCKLLYDNLRIILDDPFYDILPSMLCAGRGNGK-DACQFDSGGPLLCKSESDN---IWIVAGIVSFGFKC-GEIFPGIYTRVSSYLDWI 312
[Close]
BLAST of Serine protease vs. Planmine SMEST
Match: SMESG000004375.1 (SMESG000004375.1)

HSP 1 Score: 153.295 bits (386), Expect = 1.965e-40
Identity = 82/243 (33.74%), Postives = 135/243 (55.56%), Query Frame = 3 
Query:  330 KVFGGWRSMPGEWPWQVQIEREGAHHCGGALIHPNWVVTAAHCTFFFQDLPIEKWRIRAGKTQTNMTEPHEQNVRVKKLIDHPGFTLFTKYHDIALIQLEDPMYFDYKFVSPICLPNPQESFDDHVCTLSGYGKTESSGEGASTYLLEVNLPIISADTCQEKHCNSNSIYEENLCAGFKEGKRDACTGDSGGPIVCEKLSVNGFKQFVLAGVVSYGSGCGGKDTPGVYTRISSYLDWIEYETG 1058
            ++ GG  + PG WPW + ++    H CGG+LI  ++V+TAAHC  F  D   + + I  G+    + +   +N+ V+K+  HP + + T+  D+A+++L+         +  +C+P  +E      C + G+G T+  G G    L +  +PI+  + C E +   N I  + LCAG+K G  D+C+GDSGGP+VC+       K+F + G+VS+G GC   + PGVYT I  ++DWI+   G
Sbjct:  272 QIVGGSEANPGSWPWMISLKYGPLHMCGGSLIAEDFVLTAAHC--FIMDSNPDYYNIDLGRYF--LYKGLVENIAVEKIFLHPSYKIETQDFDLAIVKLKRKAKLTAS-IQTVCIPRDKEPIAGKKCVILGWGSTQ--GTGGEGVLKQAVVPIVERNVCNELY--GNIITNQMLCAGYKTGGIDSCSGDSGGPLVCKTE-----KKFEIYGIVSFGQGCALPNRPGVYTNIVRFVDWIDKIIG 500
[Close]
BLAST of Serine protease vs. Planmine SMEST
Match: SMESG000025034.1 (SMESG000025034.1)

HSP 1 Score: 139.428 bits (350), Expect = 3.808e-38
Identity = 85/255 (33.33%), Postives = 136/255 (53.33%), Query Frame = 3 
Query:  309 ISNGSKYKVFGGWRSMPGEWPWQVQIEREGAHHCGGALIHPNWVVTAAHCTFFFQDLPIEKWRIRAGKTQTNMTEPHEQNVRVKKLIDHPGFTLFTKYHDIALIQLEDPMYFDYKFVSPICLPNPQESFDDHVCTLSGYGKTESSGEGASTYLLEVNLPIISADTCQEKHCNSNS------IYEENLCAGFKEGKRDACTGDSGGPIVCEKLSVNGFKQFVLAGVVSYGSGCGGKDTPGVYTRISSYLDWIEYET 1055
            ++ G    + GG  +   + PW   I      HCGG++I+  W+++AAHC + ++  P++ W+I  G    ++   + + ++ K++I H  F      +DIALI+LE  +    + V PI L N  E   +  C + G+G T    +  S+ L    +P+I+   C   +C  +S      +Y+ N+CAG  +G  DAC GDSGG +VC     N  K+ VL G+VS+G GCG  + P +Y  +SSYLDWI + T
Sbjct:   15 LATGKVAFIAGGNDARIEDAPWHAAIMSGDNIHCGGSVINEKWILSAAHCFYNYRWHPMDHWKIIVG--SDDLKNKNVKFLKPKQIIIHEKFDKPFYSNDIALIELEGGINLKSQ-VKPIDLINLSEKIVESSCLVYGFGSTVK--DWWSSTLKVGQVPVINGRKCGTLYCVPSSTNEIRPVYKSNICAGNLKGGDDACEGDSGGGLVC----TNSKKRQVLVGIVSHGDGCGLPNRPTMYANVSSYLDWISFIT 260
The following BLAST results are available for this feature:
BLAST of Serine protease vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
HPN2.664e-5137.80hepsin [Source:HGNC Symbol;Acc:HGNC:5155][more]
HPN2.664e-5137.80hepsin [Source:HGNC Symbol;Acc:HGNC:5155][more]
HPN2.664e-5137.80hepsin [Source:HGNC Symbol;Acc:HGNC:5155][more]
HPN2.664e-5137.80hepsin [Source:HGNC Symbol;Acc:HGNC:5155][more]
TMPRSS35.695e-5036.78transmembrane serine protease 3 [Source:HGNC Symbo... [more]
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BLAST of Serine protease vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 4
Match NameE-valueIdentityDescription
try-15.798e-4034.69TRYpsin-like protease [Source:UniProtKB/TrEMBL;Ac... [more]
svh-14.091e-3633.47HGF/MSP/plasminogen-like protein [Source:UniProtK... [more]
try-32.233e-1531.93TRYpsin-like protease [Source:UniProtKB/TrEMBL;Ac... [more]
try-32.613e-1530.11TRYpsin-like protease [Source:UniProtKB/TrEMBL;Ac... [more]
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BLAST of Serine protease vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Sb4.030e-4336.74gene:FBgn0003319 transcript:FBtr0344008[more]
Sb4.030e-4336.74gene:FBgn0003319 transcript:FBtr0083250[more]
CG33551.240e-4234.32gene:FBgn0031619 transcript:FBtr0077376[more]
tpr1.490e-4232.67gene:FBgn0034661 transcript:FBtr0071743[more]
CG319543.034e-4235.10gene:FBgn0051954 transcript:FBtr0077563[more]
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BLAST of Serine protease vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CR352265.11.315e-4936.74pep chromosome:GRCz11:24:21813127:21819010:-1 gene... [more]
zgc:1654231.765e-4635.42zgc:165423 [Source:ZFIN;Acc:ZDB-GENE-070720-11][more]
hpn2.718e-4534.06hepsin [Source:ZFIN;Acc:ZDB-GENE-141212-373][more]
tmprss3a9.225e-4535.58transmembrane serine protease 3a [Source:ZFIN;Acc:... [more]
tmprss3a2.336e-4437.35transmembrane serine protease 3a [Source:ZFIN;Acc:... [more]
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BLAST of Serine protease vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
hpn6.916e-5136.70hepsin [Source:NCBI gene;Acc:100145343][more]
hpn3.378e-5037.80hepsin [Source:NCBI gene;Acc:100145343][more]
hpn3.564e-5037.80hepsin [Source:NCBI gene;Acc:100145343][more]
hpn7.431e-5037.80hepsin [Source:NCBI gene;Acc:100145343][more]
ENSXETT00000015569.13.450e-4833.93pep primary_assembly:Xenopus_tropicalis_v9.1:9:281... [more]
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BLAST of Serine protease vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Hpn2.450e-5138.19hepsin [Source:MGI Symbol;Acc:MGI:1196620][more]
Hpn3.684e-5138.19hepsin [Source:MGI Symbol;Acc:MGI:1196620][more]
Hpn5.677e-5138.19hepsin [Source:MGI Symbol;Acc:MGI:1196620][more]
Prss271.269e-5037.10protease, serine 27 [Source:MGI Symbol;Acc:MGI:245... [more]
Tmprss31.282e-5039.08transmembrane protease, serine 3 [Source:MGI Symbo... [more]
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BLAST of Serine protease vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q6BEA2|PRS27_RAT5.572e-5238.06Serine protease 27 OS=Rattus norvegicus OX=10116 G... [more]
sp|Q5R5E8|HEPS_PONAB9.537e-5137.80Serine protease hepsin OS=Pongo abelii OX=9601 GN=... [more]
sp|P05981|HEPS_HUMAN1.279e-5037.80Serine protease hepsin OS=Homo sapiens OX=9606 GN=... [more]
sp|O35453|HEPS_MOUSE2.577e-5038.19Serine protease hepsin OS=Mus musculus OX=10090 GN... [more]
sp|Q8BJR6|PRS27_MOUSE8.880e-5037.10Serine protease 27 OS=Mus musculus OX=10090 GN=Prs... [more]
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BLAST of Serine protease vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0S0P91.334e-5743.37Serine protease CFSP2 OS=Azumapecten farreri OX=10... [more]
A0A0S2PIU12.580e-5741.83Serine protease OS=Haliotis discus hannai OX=42344... [more]
A0A210QXI31.081e-5540.00Transmembrane protease serine 2 OS=Mizuhopecten ye... [more]
A0A267H9B26.871e-5432.96Peptidase S1 domain-containing protein OS=Macrosto... [more]
B5B2J97.954e-5435.60Serine protease OS=Pinctada fucata OX=50426 PE=2 S... [more]
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BLAST of Serine protease vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
zgc:923139.939e-5137.41serine protease 33-like [Source:NCBI gene;Acc:1111... [more]
zgc:923138.398e-5037.74serine protease 33-like [Source:NCBI gene;Acc:1111... [more]
tmprss3a2.783e-4938.10transmembrane serine protease 3 [Source:NCBI gene;... [more]
ENSAMXT00000039451.11.450e-4836.33trypsin-like [Source:NCBI gene;Acc:111192060][more]
ENSAMXT00000033802.12.446e-4833.03pep primary_assembly:Astyanax_mexicanus-2.0:3:2189... [more]
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BLAST of Serine protease vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tmprss3a6.633e-5038.65transmembrane serine protease 3a [Source:ZFIN;Acc:... [more]
ENSPMAT00000006128.12.582e-4736.11pep scaffold:Pmarinus_7.0:GL484169:9759:12797:-1 g... [more]
ENSPMAT00000001315.16.093e-4535.37pep scaffold:Pmarinus_7.0:GL479305:249343:254401:-... [more]
f105.272e-4033.33coagulation factor X [Source:ZFIN;Acc:ZDB-GENE-021... [more]
ENSPMAT00000002258.15.663e-4035.83pep scaffold:Pmarinus_7.0:GL487751:502724:507790:1... [more]
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BLAST of Serine protease vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Serine protease vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO477613.963e-4936.89Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO410351.012e-4836.90Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO396236.564e-4837.86Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO424207.427e-4636.19Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO340642.537e-4537.96Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Serine protease vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSORLT00000040448.18.248e-4935.86pep primary_assembly:ASM223467v1:8:2449519:2451077... [more]
tmprss3a4.069e-4836.54transmembrane serine protease 3 [Source:NCBI gene;... [more]
TMPRSS63.451e-4738.40transmembrane serine protease 6 [Source:NCBI gene;... [more]
TMPRSS63.453e-4738.40transmembrane serine protease 6 [Source:NCBI gene;... [more]
ENSORLT00000029619.16.367e-4734.75pep primary_assembly:ASM223467v1:8:2446843:2452083... [more]
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BLAST of Serine protease vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000044335.10.000e+0100.00SMESG000044335.1[more]
SMESG000002831.18.957e-4234.44SMESG000002831.1[more]
SMESG000022862.19.955e-4236.98SMESG000022862.1[more]
SMESG000004375.11.965e-4033.74SMESG000004375.1[more]
SMESG000025034.13.808e-3833.33SMESG000025034.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30019227 ID=SMED30019227|Name=Serine protease|organism=Schmidtea mediterranea sexual|type=transcript|length=1208bp
CTAAATTGTAGAAATATCAGATATCCATTAATGAAATAATTTTTCCAATG
TCGAGAACTAAGTGTTTGAGTTTTTTCCTGATAATTTTCTATGTTTCCCA
GGTTTTGGGTTACAAAGATGAGACACCAATTTGTTATCGAAAGTACGACG
GAGTATGTGTGCTTAAAAGTGATCCATGCCCATTTAAGGGAGAATTTGTT
GAAGTAAAACCTGAAGAAAACGAAAAGATTTGCCGAGAGGAAAGTCATAG
ATGTTGCAAACCTCTGAATAAAAATGAAAAGCCACAAAAGAGAAACAATA
AATGTGGTATAAGTAATGGATCTAAATACAAAGTTTTTGGAGGCTGGAGA
TCAATGCCAGGAGAATGGCCTTGGCAAGTACAGATCGAAAGAGAAGGAGC
TCATCATTGTGGAGGCGCCCTTATCCACCCAAATTGGGTTGTTACTGCTG
CTCATTGTACATTTTTCTTTCAAGATCTTCCAATTGAAAAATGGAGAATT
CGAGCTGGTAAAACACAAACTAACATGACTGAGCCACACGAACAAAACGT
AAGAGTTAAAAAACTGATTGATCATCCCGGGTTTACTCTCTTTACGAAAT
ATCACGACATTGCTCTCATTCAACTAGAAGATCCAATGTATTTTGATTAC
AAATTCGTTTCTCCAATTTGTCTTCCAAATCCACAAGAAAGTTTTGATGA
TCATGTTTGTACACTAAGTGGATATGGTAAAACGGAAAGTAGTGGAGAAG
GCGCGAGTACATACTTACTAGAAGTAAATTTGCCAATTATATCAGCAGAC
ACATGTCAAGAGAAACATTGCAATTCCAACTCAATTTACGAAGAAAATCT
TTGTGCTGGTTTTAAAGAAGGTAAAAGAGATGCTTGCACAGGGGATAGTG
GAGGACCTATTGTCTGTGAAAAGTTATCAGTAAATGGTTTCAAACAATTT
GTGTTGGCAGGAGTCGTTTCTTACGGAAGCGGTTGTGGGGGCAAAGACAC
TCCCGGGGTTTATACTAGAATTTCTTCATATTTGGATTGGATTGAATATG
AAACGGGCATTGAAGTATCAACAGGAAAGTTTACAATGGCAACCCAATTC
ACGCCAGAGGCTGTTAAGAGAGTTGTAACAGACAAGTGCAAACCAGATAA
ATAAATTAAATGAACGTTTTGAAATTTGAATAAAAACTTCAGTTTTGTCA
AAAAAAAA
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protein sequence of SMED30019227-orf-1

>SMED30019227-orf-1 ID=SMED30019227-orf-1|Name=SMED30019227-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=369bp
MSRTKCLSFFLIIFYVSQVLGYKDETPICYRKYDGVCVLKSDPCPFKGEF
VEVKPEENEKICREESHRCCKPLNKNEKPQKRNNKCGISNGSKYKVFGGW
RSMPGEWPWQVQIEREGAHHCGGALIHPNWVVTAAHCTFFFQDLPIEKWR
IRAGKTQTNMTEPHEQNVRVKKLIDHPGFTLFTKYHDIALIQLEDPMYFD
YKFVSPICLPNPQESFDDHVCTLSGYGKTESSGEGASTYLLEVNLPIISA
DTCQEKHCNSNSIYEENLCAGFKEGKRDACTGDSGGPIVCEKLSVNGFKQ
FVLAGVVSYGSGCGGKDTPGVYTRISSYLDWIEYETGIEVSTGKFTMATQ
FTPEAVKRVVTDKCKPDK*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000418head
PLANA:0000420parapharyngeal region
Vocabulary: INTERPRO
TermDefinition
IPR001314Peptidase_S1A
IPR001254Trypsin_dom
IPR033116TRYPSIN_SER
IPR018114TRYPSIN_HIS
IPR009003Peptidase_S1_PA
Vocabulary: molecular function
TermDefinition
GO:0004252serine-type endopeptidase activity
GO:0005044scavenger receptor activity
GO:0008233peptidase activity
GO:0008236serine-type peptidase activity
GO:0016787hydrolase activity
GO:0017080sodium channel regulator activity
Vocabulary: biological process
TermDefinition
GO:0006508proteolysis
GO:0006883cellular sodium ion homeostasis
GO:0006898receptor-mediated endocytosis
GO:0007605sensory perception of sound
GO:0065009regulation of molecular function
Vocabulary: cellular component
TermDefinition
GO:0005783endoplasmic reticulum
GO:0005789endoplasmic reticulum membrane
GO:0016020membrane
GO:0016021integral component of membrane
GO:0043025neuronal cell body
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001314Peptidase S1A, chymotrypsin familyPRINTSPR00722CHYMOTRYPSINcoord: 122..137
score: 60.96
coord: 277..289
score: 63.54
coord: 183..197
score: 35.99
IPR001254Serine proteases, trypsin domainSMARTSM00020trypsin_2coord: 95..332
e-value: 1.5E-81
score: 286.9
IPR001254Serine proteases, trypsin domainPFAMPF00089Trypsincoord: 97..332
e-value: 1.9E-62
score: 211.0
IPR001254Serine proteases, trypsin domainPROSITEPS50240TRYPSIN_DOMcoord: 96..337
score: 34.814
IPR001254Serine proteases, trypsin domainCDDcd00190Tryp_SPccoord: 96..333
e-value: 6.2734E-89
score: 265.679
NoneNo IPR availableGENE3DG3DSA:2.40.10.10coord: 88..337
e-value: 1.3E-76
score: 259.2
NoneNo IPR availablePANTHERPTHR24253FAMILY NOT NAMEDcoord: 59..336
NoneNo IPR availableSIGNALP_EUKSignalP-noTMSignalP-noTMcoord: 1..21
score: 0.856
IPR033116Serine proteases, trypsin family, serine active sitePROSITEPS00135TRYPSIN_SERcoord: 278..289
IPR018114Serine proteases, trypsin family, histidine active sitePROSITEPS00134TRYPSIN_HIScoord: 132..137
IPR009003Peptidase S1, PA clanSUPERFAMILYSSF50494Trypsin-like serine proteasescoord: 69..337