Cytochrome b561/ferric reductase transmembrane,domain-containing protein

Overview
NameCytochrome b561/ferric reductase transmembrane,domain-containing protein
Smed IDSMED30019200
Length (bp)1812
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Cytochrome b561/ferric reductase transmembrane,domain-containing protein (SMED30019200) t-SNE clustered cells

Violin plots show distribution of expression levels for Cytochrome b561/ferric reductase transmembrane,domain-containing protein (SMED30019200) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Cytochrome b561/ferric reductase transmembrane,domain-containing protein (SMED30019200) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Cytochrome b561/ferric reductase transmembrane,domain-containing protein (SMED30019200) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30019200

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 7

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
Smed sexual biotypeSMED30019200h1SMcG0015272 Contig32677newmark_estsPMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30019200h1SMcG0015272 Contig32677uc_Smed_v2PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30019200h1SMcG0015272 Contig48989uc_Smed_v2PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30019200h1SMcG0015272 Contig48989newmark_estsPMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
cephalic gangliaSMED30019200h1SMcG0015272 dd_Smed_v4_4028_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30019200h1SMcG0015272 dd_Smed_v4_4028_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
anterior sideSMED30019200h1SMcG0015272 dd_Smed_v4_4028_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Cytochrome b561/ferric reductase transmembrane,domain-containing protein vs. Ensembl Human
Match: FRRS1 (ferric chelate reductase 1 [Source:HGNC Symbol;Acc:HGNC:27622])

HSP 1 Score: 126.716 bits (317), Expect = 4.597e-30
Identity = 113/427 (26.46%), Postives = 185/427 (43.33%), Query Frame = 2
Query:  128 LVFIISLVFVCDALESMSFQTCESEKACFKSSKYCTYD---SCDFAISWKPFSYMNNDY-IEFEMVGTVFGDNSYMLVGFSDDTSLGNDGFVSCHVESKKVKVVAGFYEVGDTPESNIKFS-NDVSLLVANSDKRYGGVYNEDTKRLTCRFLRQTRPQNANNQYKDLSLGNEYYLFTARGNEASQYGYGPPTAGSLIFSKHPIDFSRGSFHGVIGESSRVDSSFAKTHGILMVIAWVFCSSVGVILARYYKEMWPYTGIAKEMVWFQFHRSLQGTCVLLTTVAFILIFASVGGYSKLDRSPYVAHPILGIIVFILAFLNPLVALCRCRPNSKDRPWFNWFHFFIGSIAYCLSVPTIMIGMRISGPGRQLAYLESPQWILIFFVLFQFAVEIILEIHGCLYYRRNKDKKHTYEMEMEEYQAALIANHA 1393
            +V + +L  V    +  S   C ++K C +S   C  +   SC F       S+  +D  +  EM G   G   Y+    S D  +G+D    C  E + V +          P  + + +  D++  +A+      GV       + C F R        N++    L   YY+F A G       Y       + + K+ +  S  +    IG S  V     K HG LM +AW+   S+GV++AR++K +W    +  E  WFQ HR L  T  +LT +AF++ F   GG+S+   + Y  HP LG IV  LA L PL+A+ R   +   R  FNW H+ +G+ A  ++V  + +GM + G     ++     + +  FV +    E++LE+H     R+ +         ++ + A     HA
Sbjct:  177 VVPLPTLPPVSHLTKPFSASDCGNKKFCIRSPLNCDPEKEASCVF------LSFTRDDQSVMVEMSGPSKG---YLSFALSHDQWMGDDDAYLCIHEDQTVYIQPSHLTGRSHPVMDSRDTLEDMAWRLAD------GV-------MQCSFRRNITLPGVKNRF---DLNTSYYIFLADGAANDGRIYKHSQQPLITYEKYDVTDSPKN----IGGSHSV--LLLKVHGALMFVAWMTTVSIGVLVARFFKPVWSKAFLLGEAAWFQVHRMLMFTTTVLTCIAFVMPFIYRGGWSR--HAGY--HPYLGCIVMTLAVLQPLLAVFRPPLHDPRRQMFNWTHWSMGTAARIIAVAAMFLGMDLPGLNLPDSW---KTYAMTGFVAWHVGTEVVLEVHAYRLSRKVEILDDDRIQILQSFTAVETEGHA 565          
BLAST of Cytochrome b561/ferric reductase transmembrane,domain-containing protein vs. Ensembl Human
Match: FRRS1 (ferric chelate reductase 1 [Source:HGNC Symbol;Acc:HGNC:27622])

HSP 1 Score: 122.094 bits (305), Expect = 1.869e-28
Identity = 108/395 (27.34%), Postives = 175/395 (44.30%), Query Frame = 2
Query:  128 LVFIISLVFVCDALESMSFQTCESEKACFKSSKYCTYD---SCDFAISWKPFSYMNNDY-IEFEMVGTVFGDNSYMLVGFSDDTSLGNDGFVSCHVESKKVKVVAGFYEVGDTPESNIKFS-NDVSLLVANSDKRYGGVYNEDTKRLTCRFLRQTRPQNANNQYKDLSLGNEYYLFTARGNEASQYGYGPPTAGSLIFSKHPIDFSRGSFHGVIGESSRVDSSFAKTHGILMVIAWVFCSSVGVILARYYKEMWPYTGIAKEMVWFQFHRSLQGTCVLLTTVAFILIFASVGGYSKLDRSPYVAHPILGIIVFILAFLNPLVALCRCRPNSKDRPWFNWFHFFIGSIAYCLSVPTIMIGMRISGPGRQLAYLESPQWILIFFVLFQFAVEIILEI 1297
            +V + +L  V    +  S   C ++K C +S   C  +   SC F       S+  +D  +  EM G   G   Y+    S D  +G+D    C  E + V +          P  + + +  D++  +A+      GV       + C F R        N++    L   YY+F A G       Y       + + K+ +  S  +    IG S  V     K HG LM +AW+   S+GV++AR++K +W    +  E  WFQ HR L  T  +LT +AF++ F   GG+S+   + Y  HP LG IV  LA L PL+A+ R   +   R  FNW H+ +G+ A  ++V  + +GM + G     ++     + +  FV +    E++LE+
Sbjct:  177 VVPLPTLPPVSHLTKPFSASDCGNKKFCIRSPLNCDPEKEASCVF------LSFTRDDQSVMVEMSGPSKG---YLSFALSHDQWMGDDDAYLCIHEDQTVYIQPSHLTGRSHPVMDSRDTLEDMAWRLAD------GV-------MQCSFRRNITLPGVKNRF---DLNTSYYIFLADGAANDGRIYKHSQQPLITYEKYDVTDSPKN----IGGSHSV--LLLKVHGALMFVAWMTTVSIGVLVARFFKPVWSKAFLLGEAAWFQVHRMLMFTTTVLTCIAFVMPFIYRGGWSR--HAGY--HPYLGCIVMTLAVLQPLLAVFRPPLHDPRRQMFNWTHWSMGTAARIIAVAAMFLGMDLPGLNLPDSW---KTYAMTGFVAWHVGTEVVLEL 533          
BLAST of Cytochrome b561/ferric reductase transmembrane,domain-containing protein vs. Ensembl Human
Match: FRRS1L (ferric chelate reductase 1 like [Source:HGNC Symbol;Acc:HGNC:1362])

HSP 1 Score: 56.6102 bits (135), Expect = 5.272e-8
Identity = 54/192 (28.12%), Postives = 90/192 (46.88%), Query Frame = 2
Query:  161 DALESMSFQTCESEKACFKSSKY-CTYDSCDFAISWKPFSYMNNDYIEFEMVGTVFGDNSYMLVGFSDDTSLGNDGFVSC-HVESKKVKVVAGFYEVGDTPESNIKFSNDVSLLVANSDKRYGGVYNEDTKRLTCRFLRQTRPQNA--NNQYKDLSLGNEYYLFTARGNEASQYGYGPPTAGSLIFSKHPID 724
            D    +    C   K CF+  K  C  ++CD+ +S++    M    +EFE+     G   ++ VGFS D  +G D  ++C H ++ +V+ +  FY VG       +++ ++    A  ++   GV+  +  R+TCRF    RP N   +    DL L + YYLF           +GP   GS+  ++H ID
Sbjct:  141 DPFAKIKVDDCGKTKGCFRYGKPGCNAETCDYFLSYR----MIGADVEFELSADTDG---WVAVGFSSDKKMGGDDVMACVHDDNGRVR-IQHFYNVG-------QWAKEIQRNPARDEE---GVF--ENNRVTCRF---KRPVNVPRDETIVDLHL-SWYYLF----------AWGPAIQGSI--TRHDID 296          
BLAST of Cytochrome b561/ferric reductase transmembrane,domain-containing protein vs. Ensembl Celegans
Match: C05D12.1 (pep chromosome:WBcel235:II:11412232:11415820:-1 gene:WBGene00007339.1 transcript:C05D12.1.3 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:C05D12.1)

HSP 1 Score: 105.145 bits (261), Expect = 1.036e-23
Identity = 89/351 (25.36%), Postives = 140/351 (39.89%), Query Frame = 2
Query:  338 YMLVGFSDDTSLGNDGFVSC---HVESKKVKVVAGFYEVGDTPESNIKFSNDVSLLVANSDKRYGGVYNEDTKRLTC--RFLRQTRPQNANN---QYKDLSLGNEYYLFTARG--------------NEASQYGYGPPTAGSLIFSK--HPIDFSRGSFHGVIGESSRVDSSFAKTHGILMVIAWVFCSSVGVILARYYKEMWPYTGIAKEMVWFQFHRSLQGTCVLLTTVAFILIFASVGG-------YSKLDRSPYVAHPILGIIVFILAFLNPLVALCRCRPNSKDRPWFNWFHFFIGSIAYCLSVPTIMIGMRISGPGRQLAYLESPQWILIFFVLFQFAVEIILEI 1297
            Y  +GFS +  + +D    C   H    KV++        D   + +       LL   +     GV       LTC  + L   RP   N+      DL  G+ Y+L  ARG              N+  Q+ +      S   +    P  +  G        S       A  HGIL++ AW   +S  ++++RY+K ++P   +    VWFQ HR +    V++  +  + IF   G            D      H I G    +LA L P+    R  P S  RP FNW H+ +G  ++ ++  TI++ + +   G    Y   P WI++ ++LF  A  +ILEI
Sbjct:   82 YAALGFSFNQRMDDDTVFECVVPHTGDGKVQI-----SFNDETFNQVLPQGSSVLLTEGTTSYVDGV-------LTCSAKLLLDNRPLIDNDTQFMVHDLESGS-YHLLFARGSANKYTLEKDIHSTNDGQQFPWMSDEQVSFCRTNCSSPNLYHIGEMRQTYNVSRYWRYRIAVWHGILLMFAWWVLASNAILISRYFKPLFPRNKLLGTAVWFQLHRDMMILSVVIQVICVLFIFYQAGWVWYQCSYMCTSDDFSKKMHGITGFTATVLALLQPVFGFLRPSPTSSIRPIFNWGHWLVGMFSWSVASATIVLALPMGKTGLNRLYGHVPNWIVLGYILFFIACNLILEI 419          
BLAST of Cytochrome b561/ferric reductase transmembrane,domain-containing protein vs. Ensembl Celegans
Match: C05D12.1 (pep chromosome:WBcel235:II:11412253:11415729:-1 gene:WBGene00007339.1 transcript:C05D12.1.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:C05D12.1)

HSP 1 Score: 105.145 bits (261), Expect = 1.036e-23
Identity = 89/351 (25.36%), Postives = 140/351 (39.89%), Query Frame = 2
Query:  338 YMLVGFSDDTSLGNDGFVSC---HVESKKVKVVAGFYEVGDTPESNIKFSNDVSLLVANSDKRYGGVYNEDTKRLTC--RFLRQTRPQNANN---QYKDLSLGNEYYLFTARG--------------NEASQYGYGPPTAGSLIFSK--HPIDFSRGSFHGVIGESSRVDSSFAKTHGILMVIAWVFCSSVGVILARYYKEMWPYTGIAKEMVWFQFHRSLQGTCVLLTTVAFILIFASVGG-------YSKLDRSPYVAHPILGIIVFILAFLNPLVALCRCRPNSKDRPWFNWFHFFIGSIAYCLSVPTIMIGMRISGPGRQLAYLESPQWILIFFVLFQFAVEIILEI 1297
            Y  +GFS +  + +D    C   H    KV++        D   + +       LL   +     GV       LTC  + L   RP   N+      DL  G+ Y+L  ARG              N+  Q+ +      S   +    P  +  G        S       A  HGIL++ AW   +S  ++++RY+K ++P   +    VWFQ HR +    V++  +  + IF   G            D      H I G    +LA L P+    R  P S  RP FNW H+ +G  ++ ++  TI++ + +   G    Y   P WI++ ++LF  A  +ILEI
Sbjct:   82 YAALGFSFNQRMDDDTVFECVVPHTGDGKVQI-----SFNDETFNQVLPQGSSVLLTEGTTSYVDGV-------LTCSAKLLLDNRPLIDNDTQFMVHDLESGS-YHLLFARGSANKYTLEKDIHSTNDGQQFPWMSDEQVSFCRTNCSSPNLYHIGEMRQTYNVSRYWRYRIAVWHGILLMFAWWVLASNAILISRYFKPLFPRNKLLGTAVWFQLHRDMMILSVVIQVICVLFIFYQAGWVWYQCSYMCTSDDFSKKMHGITGFTATVLALLQPVFGFLRPSPTSSIRPIFNWGHWLVGMFSWSVASATIVLALPMGKTGLNRLYGHVPNWIVLGYILFFIACNLILEI 419          
BLAST of Cytochrome b561/ferric reductase transmembrane,domain-containing protein vs. Ensembl Celegans
Match: C05D12.1 (pep chromosome:WBcel235:II:11412253:11415772:-1 gene:WBGene00007339.1 transcript:C05D12.1.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:C05D12.1)

HSP 1 Score: 105.145 bits (261), Expect = 1.036e-23
Identity = 89/351 (25.36%), Postives = 140/351 (39.89%), Query Frame = 2
Query:  338 YMLVGFSDDTSLGNDGFVSC---HVESKKVKVVAGFYEVGDTPESNIKFSNDVSLLVANSDKRYGGVYNEDTKRLTC--RFLRQTRPQNANN---QYKDLSLGNEYYLFTARG--------------NEASQYGYGPPTAGSLIFSK--HPIDFSRGSFHGVIGESSRVDSSFAKTHGILMVIAWVFCSSVGVILARYYKEMWPYTGIAKEMVWFQFHRSLQGTCVLLTTVAFILIFASVGG-------YSKLDRSPYVAHPILGIIVFILAFLNPLVALCRCRPNSKDRPWFNWFHFFIGSIAYCLSVPTIMIGMRISGPGRQLAYLESPQWILIFFVLFQFAVEIILEI 1297
            Y  +GFS +  + +D    C   H    KV++        D   + +       LL   +     GV       LTC  + L   RP   N+      DL  G+ Y+L  ARG              N+  Q+ +      S   +    P  +  G        S       A  HGIL++ AW   +S  ++++RY+K ++P   +    VWFQ HR +    V++  +  + IF   G            D      H I G    +LA L P+    R  P S  RP FNW H+ +G  ++ ++  TI++ + +   G    Y   P WI++ ++LF  A  +ILEI
Sbjct:   82 YAALGFSFNQRMDDDTVFECVVPHTGDGKVQI-----SFNDETFNQVLPQGSSVLLTEGTTSYVDGV-------LTCSAKLLLDNRPLIDNDTQFMVHDLESGS-YHLLFARGSANKYTLEKDIHSTNDGQQFPWMSDEQVSFCRTNCSSPNLYHIGEMRQTYNVSRYWRYRIAVWHGILLMFAWWVLASNAILISRYFKPLFPRNKLLGTAVWFQLHRDMMILSVVIQVICVLFIFYQAGWVWYQCSYMCTSDDFSKKMHGITGFTATVLALLQPVFGFLRPSPTSSIRPIFNWGHWLVGMFSWSVASATIVLALPMGKTGLNRLYGHVPNWIVLGYILFFIACNLILEI 419          
BLAST of Cytochrome b561/ferric reductase transmembrane,domain-containing protein vs. Ensembl Celegans
Match: C13B4.1 (pep chromosome:WBcel235:II:14470371:14479627:-1 gene:WBGene00007545.1 transcript:C13B4.1a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:C13B4.1)

HSP 1 Score: 103.99 bits (258), Expect = 6.861e-23
Identity = 105/411 (25.55%), Postives = 164/411 (39.90%), Query Frame = 2
Query:  188 TCESEKACFKSSKYCTYDSCDFAISWKPFSYMNNDYIEFEMVGTVFGDNS-YMLVGFSDDTSLGNDGFVSC-----HVESKKVKVVAGFYEVGDTPESNIKFSNDVSLLVANSDKRY--GGVYNEDTKRLTCRFLRQTRPQNANNQYKDLSLGNEYYLFTARGNEASQYGYGPPTAGSLIFSKHPI-DFSRGSFHGVIGESSRVDSSFAKTHGILMVIAWVFCSSVGVILARYYKEMWPYTGIAKEMVWFQFHRSLQGTCVLLTTVAFILI-------FASVGGYSKLDRSPYVAHPILGIIVFILAFLNPLVALCRCRPNSKDRPWFNWFHFFIGSIAYCLSVPTIMI-GMRISGPGR---QLAYLESPQWILIFFVLFQFAVEIILEIHGCLYYRRNKDKKHTYEMEME 1360
            TC  +KAC+        D+  + +       +N+ YIEFE+  T    +  Y  +GFS+D  +     + C        S K    +G+     + E  I+     S  + N++  Y  G +Y + T R            N+N      +   +Y+L  A+G  AS  G G       I +   + D   G+  G         ++    H + M IAW+    + VI AR  +  WP T     ++WF  HR      + L   AF+LI       F ++G   K        H I+GII   LA+L P ++  RC PN   RP FN+ H  IG  A  L+   I I G   +G GR   QL     P  ++    LF      ++++    + + N     T ++ M 
Sbjct:  574 TCGKDKACYTPPN--NVDTVAYKV-------LNDSYIEFEISSTQSSSSGVYTALGFSNDGKMNPANVIECSSLGSQPLSMKFSTNSGYSNDRISGEEAIR-----SQYITNTETSYVDGKIYCKGTVR---------SDGNSNAAIFKYTPKQQYHLIIAKGT-ASPGGLGYHGTNRYISTARLLTDLGAGNESGS-------SNTLLILHAMFMTIAWMTMVPIAVIFARVLRSSWPTTKPGGLLIWFHIHRGANLIGIALMIAAFVLILIHKDWKFTTIGWGGK--------HAIIGIIALCLAWLQPFISTLRCSPNDSRRPIFNYIHRGIGVTAMVLATTAICIAGYHFTG-GRHVVQLVLALIPISVIFALSLFFIIFNNVVDVDTKSFTKTNGASARTEDIPMR 944          

HSP 2 Score: 50.8322 bits (120), Expect = 2.848e-6
Identity = 35/125 (28.00%), Postives = 61/125 (48.80%), Query Frame = 2
Query:  140 ISLVFVCDALESMSFQ--TCESEKACFKSSKYCTYDSCDFAISWKPFSYMNNDYIEFEMVGTVFGDNSYMLVGFSDDTSLGNDGFVSCHVESKKVKVVAGFYEVGDTPE-SNIKFSNDVSLLVAN 505
            +S++   D + ++ F   TC   K CF  +  CT    D   SW   S ++++ I  E+ G V   N Y+ +GFS + ++GN   + C         +   Y + + P+ SN++ ++DVS L  N
Sbjct:  363 VSILTFLDQVNNLGFNDATCGLTKGCFTPTD-CTDGCDDIRSSW---SLLSDNQIHVELTGKVNATNKYVAMGFSTNGTMGNTSVIECSSFDNSNFSMTFSYNLVNAPDYSNLRSTSDVSGLFTN 483          
BLAST of Cytochrome b561/ferric reductase transmembrane,domain-containing protein vs. Ensembl Celegans
Match: C13B4.1 (pep chromosome:WBcel235:II:14470523:14479627:-1 gene:WBGene00007545.1 transcript:C13B4.1b.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:C13B4.1)

HSP 1 Score: 97.4413 bits (241), Expect = 9.185e-21
Identity = 90/343 (26.24%), Postives = 137/343 (39.94%), Query Frame = 2
Query:  188 TCESEKACFKSSKYCTYDSCDFAISWKPFSYMNNDYIEFEMVGTVFGDNS-YMLVGFSDDTSLGNDGFVSC-----HVESKKVKVVAGFYEVGDTPESNIKFSNDVSLLVANSDKRY--GGVYNEDTKRLTCRFLRQTRPQNANNQYKDLSLGNEYYLFTARGNEASQYGYGPPTAGSLIFSKHPI-DFSRGSFHGVIGESSRVDSSFAKTHGILMVIAWVFCSSVGVILARYYKEMWPYTGIAKEMVWFQFHRSLQGTCVLLTTVAFILI-------FASVGGYSKLDRSPYVAHPILGIIVFILAFLNPLVALCRCRPNSKDRPWFNWFHFFIGSIAYCLS 1168
            TC  +KAC+              +    +  +N+ YIEFE+  T    +  Y  +GFS+D  +     + C        S K    +G+     + E  I+     S  + N++  Y  G +Y + T R            N+N      +   +Y+L  A+G  AS  G G       I +   + D   G+  G         ++    H + M IAW+    + VI AR  +  WP T     ++WF  HR      + L   AF+LI       F ++G   K        H I+GII   LA+L P ++  RC PN   RP FN+ H  IG  A  L+
Sbjct:  574 TCGKDKACYTPPN---------NVDTVAYKVLNDSYIEFEISSTQSSSSGVYTALGFSNDGKMNPANVIECSSLGSQPLSMKFSTNSGYSNDRISGEEAIR-----SQYITNTETSYVDGKIYCKGTVR---------SDGNSNAAIFKYTPKQQYHLIIAKG-TASPGGLGYHGTNRYISTARLLTDLGAGNESGS-------SNTLLILHAMFMTIAWMTMVPIAVIFARVLRSSWPTTKPGGLLIWFHIHRGANLIGIALMIAAFVLILIHKDWKFTTIGWGGK--------HAIIGIIALCLAWLQPFISTLRCSPNDSRRPIFNYIHRGIGVTAMVLA 877          

HSP 2 Score: 50.447 bits (119), Expect = 3.787e-6
Identity = 35/125 (28.00%), Postives = 61/125 (48.80%), Query Frame = 2
Query:  140 ISLVFVCDALESMSFQ--TCESEKACFKSSKYCTYDSCDFAISWKPFSYMNNDYIEFEMVGTVFGDNSYMLVGFSDDTSLGNDGFVSCHVESKKVKVVAGFYEVGDTPE-SNIKFSNDVSLLVAN 505
            +S++   D + ++ F   TC   K CF  +  CT    D   SW   S ++++ I  E+ G V   N Y+ +GFS + ++GN   + C         +   Y + + P+ SN++ ++DVS L  N
Sbjct:  363 VSILTFLDQVNNLGFNDATCGLTKGCFTPTD-CTDGCDDIRSSW---SLLSDNQIHVELTGKVNATNKYVAMGFSTNGTMGNTSVIECSSFDNSNFSMTFSYNLVNAPDYSNLRSTSDVSGLFTN 483          
BLAST of Cytochrome b561/ferric reductase transmembrane,domain-containing protein vs. Ensembl Fly
Match: CG8399 (gene:FBgn0034067 transcript:FBtr0087207)

HSP 1 Score: 145.591 bits (366), Expect = 1.515e-36
Identity = 114/404 (28.22%), Postives = 186/404 (46.04%), Query Frame = 2
Query:  182 FQTCESEKACFKSSKYCTYDSCDFAISWKPFSYMNNDYIEFEMVGTVFGDNSYMLVGFSDDTSLGNDGFVSCHVESKKVKVVAGFYEVGDTPESNIKFS-NDVSLLVANSDKRYGGVYNEDTKRLTCRFLRQTRPQNANNQYKDLSLGNEYYLFTARGNEASQYGYGPPTAGSLIFSKHPIDFSRGSFHGVIGESSRVDSSFAKTHGILMVIAWVFCSSVGVILARYYKEMWPYTGIAKEMVWFQFHRSLQGTCVLLTTVAFILIFASVGGYSKLDRSPYVAHPILGIIVFILAFLNPLVALCRCRPNSKDRPWFNWFHFFIGSIAYCLSVPTIMIGMRISGPGRQLAYLESPQWILIFFVLFQFAVEIILEIHGCLYYRRNKDKKHTYEM-EMEEYQAALIAN 1387
            +  C   K CF     C       +I+      +  D  EFE+      + +Y+ VG SDD  +G+D    C  E+ +V + +       +P S ++ + N  S  + ++    G +Y        CR  R     N   +  DL  G +Y+L  A G+   +   G    G L  S  PI+ +       + + S       + HG  M+ AW+  +S+G+I ARY+K+ W  +       WF +HR L  T   LT  A++LI+       +L ++ + AH I+G+I  IL F+ P+ AL R  PN K RP+FNW H+  G++A+ L + TI   +++  P  +L   E   WIL+ FV+    V +I  I G    R    + +T++M +M  +Q   + N
Sbjct:  226 YNGCGQSKNCFGFPDGCVATKSCTSIT---VVTVRGDVFEFEIQSGKGTNAAYVAVGLSDDAKMGDDLTTECVPENGRVNLYSSLTSA--SPYSAVRSNVNQNSARLLDASIVDGVIY--------CRVQRDAV-TNVQGRTFDLRNG-KYHLLVASGSSLKENSVGYHDIGRLP-SAQPINLAE------VQDLSGSSRLLIQLHGAFMIAAWIGTTSLGIIFARYFKQTWVGSQSCGTDQWFAWHRLLMVTTWSLTVAAYVLIWV------ELKQAVWHAHSIIGLITVILCFIQPIGALFRPGPNDKKRPYFNWGHWLGGNLAHILGIVTIFFSVKL--PKAELP--EWMDWILVSFVVVHVLVHLIFSIGGMASERHLSQRANTFQMGDMSHHQQHAMRN 597          
BLAST of Cytochrome b561/ferric reductase transmembrane,domain-containing protein vs. Ensembl Fly
Match: CG8399 (gene:FBgn0034067 transcript:FBtr0340018)

HSP 1 Score: 141.354 bits (355), Expect = 3.941e-35
Identity = 115/413 (27.85%), Postives = 188/413 (45.52%), Query Frame = 2
Query:  182 FQTCESEKACFKSSKYCTYDSCDFAISWKPFSYMNNDYIEFEMVGTVFGDNSYMLVGFSDDTSLGNDGFVSCHVESKKVKVVAGFYEVGDTPESNIKFS-NDVSLLVANSDKRYGGVYNEDTKRLTCRFLRQTRPQNANNQYKDLSLGNEYYLFTARGNEASQYGYGPPTAGSLIFSKHPIDFSRGSFHGVIGESSRVDSSFAKTHGILMVIAWVFCSSVGVILARYYKEMWPYTGIAKEMVWFQFHRSLQGTCVLLTTVAFILIFASVGGYSKLDRSPYVAHPILGIIVFILAFLNPLVALCRCRPNSKDRPWFNWFHFFIGSIAYCLSVPTIMIGMRISGPGRQLAYLESPQWILIFFVLFQFAVEIILEIHGCLYY---------RRNKDKKHTYEM-EMEEYQAALIAN 1387
            +  C   K CF     C       +I+      +  D  EFE+      + +Y+ VG SDD  +G+D    C  E+ +V + +       +P S ++ + N  S  + ++    G +Y        CR  R     N   +  DL  G +Y+L  A G+   +   G    G L  S  PI+ +       + + S       + HG  M+ AW+  +S+G+I ARY+K+ W  +       WF +HR L  T   LT  A++LI+       +L ++ + AH I+G+I  IL F+ P+ AL R  PN K RP+FNW H+  G++A+ L + TI   +++  P  +L   E   WIL+ FV+    V +I  I  CL +         R    + +T++M +M  +Q   + N
Sbjct:  226 YNGCGQSKNCFGFPDGCVATKSCTSIT---VVTVRGDVFEFEIQSGKGTNAAYVAVGLSDDAKMGDDLTTECVPENGRVNLYSSLTSA--SPYSAVRSNVNQNSARLLDASIVDGVIY--------CRVQRDAV-TNVQGRTFDLRNG-KYHLLVASGSSLKENSVGYHDIGRLP-SAQPINLAE------VQDLSGSSRLLIQLHGAFMIAAWIGTTSLGIIFARYFKQTWVGSQSCGTDQWFAWHRLLMVTTWSLTVAAYVLIWV------ELKQAVWHAHSIIGLITVILCFIQPIGALFRPGPNDKKRPYFNWGHWLGGNLAHILGIVTIFFSVKL--PKAELP--EWMDWILVSFVVVHVLVHLIFSIGLCLNHWQIGGMASERHLSQRANTFQMGDMSHHQQHAMRN 606          
BLAST of Cytochrome b561/ferric reductase transmembrane,domain-containing protein vs. Ensembl Zebrafish
Match: frrs1a (ferric-chelate reductase 1a [Source:ZFIN;Acc:ZDB-GENE-070705-45])

HSP 1 Score: 136.732 bits (343), Expect = 9.992e-34
Identity = 119/386 (30.83%), Postives = 178/386 (46.11%), Query Frame = 2
Query:  167 LESMSFQTCESEKACFKSSKYC--TYDSCDFAISWKPFSYMNNDYIEFEMVGTVFGDNSYMLVGFSDDTSLGNDGFVSCHVESKKVKVVAGFYEVGDTPE-SNIKFSNDVSLLVANSDKRYGGVYNEDTKRLTCRFLRQT-RPQNANNQYKDLSLGNEYYLFTARGNEASQYGY-GPPTAGSLIFSKHPIDFSRGSFHGVIGESSRVDSSFAKTHGILMVIAWVFCSSVGVILARYYKEMWPYTGIAKEMVWFQFHRSLQGTCVLLTTVAFILIFASVGGYSKLDRSPYVAHPILGIIVFILAFLNPLVALCRCRPNSKDRPWFNWFHFFIGSIAYCLSVPTIMIGMRISGPGRQLAYLESPQW---ILIFFVLFQFAVEIILEIH 1300
            L   S   C  +K C      C  + D+  F +++      +   + FE+ G   G   Y+    S D  +G+D    C  +  +V V A +      P+ S+     DV   V++      G+       + C+F R    PQ+     +  SL N YYLF A G  +++YG     T   LI S H +         VI   SR      K HG LM+IAW+   S G ++A Y+K  WP   +  + +WFQ HR L    VLLT+V FI+ F   G +S        AHP LG  V ILAF  PL+A  R  P+S  R  FNW H+ +G+ A  ++V +I +G++     +Q   L  P W   IL  FV++   ++++L++H
Sbjct:  188 LSQFSSDGCGRQKTCLLDPVGCNPSVDTNCFYLAYS----TSGQTVSFELSGPAQG---YVSFALSSDKWMGDDDVYLCVYDGGRVSVEAAYTTGRTYPKVSSQSVLMDVGWRVSD------GI-------IQCKFSRSIYTPQDP----ERFSLNNSYYLFIAHG--SAEYGMIHRHTRQPLISSHHQVIIGPP----VILTGSR-SPLLMKYHGALMLIAWMLAGSTGTLMAGYFKPDWPEQTLFGQKIWFQVHRMLMSLTVLLTSVGFIVPFIYRGKWSTRAG----AHPYLGCTVMILAFCQPLMAAFRPAPDSPRRWIFNWLHWGVGNAAEIIAVGSIFLGIK-----QQSLLLPYP-WTTGILSAFVVWTIVLKLVLQLH 532          
BLAST of Cytochrome b561/ferric reductase transmembrane,domain-containing protein vs. Ensembl Zebrafish
Match: frrs1b (ferric-chelate reductase 1b [Source:ZFIN;Acc:ZDB-GENE-080917-44])

HSP 1 Score: 133.65 bits (335), Expect = 8.104e-33
Identity = 105/318 (33.02%), Postives = 150/318 (47.17%), Query Frame = 2
Query:  377 NDGFVSCHVESKKVKVVAGFYEVGDTPESNIKFSNDVSLLVANSDKRYGGVYNEDTKRLT-----CRFLRQTR--PQNANNQYKDLSLGNEYYLFTARGNEASQYGYGPPTAGSLIFSKHPIDFSRGSFHGVIGESSRVDSSFAKTHGILMVIAWVFCSSVGVILARYYKEMWPYTGIAKEMVWFQFHRSLQGTCVLLTTVAFILIFASVGGYSKLDRSPYVAHPILGIIVFILAFLNPLVALCRCRPNSKDRPWFNWFHFFIGSIAYCLSVPTIMIGMRISGPGRQLAYLESPQW---ILIFFVLFQFAVEIILEIH 1300
            ND   +CH  S + +  +  +E+    E  + F        A S  ++  V  +   RL+     C F R     P++ N      SL   YYLF A G   +  G         + S    D + GS   + G  S +     K HG LM+IAW    + GVI+ARY+K  WP   I  + VWFQ HR L    VLLT VAF+L F   GG+SK        HP LG +V  L  + P++AL R  P++  R  FNW HF  G+ A  ++V TI +G+      +Q  +L SP W   +L F V++    +++LE+H
Sbjct:  218 NDA--ACHFLSFRAESNSVMFELSGPAEGYVSF--------ALSLDKWMNVLKDRAWRLSDGVIQCSFRRDVHQPPEDLNR----FSLDQMYYLFMAHGR--ADDGRTHRHDRQPLISASQTDMT-GSPKEIGGSRSPL---LMKFHGALMLIAWTSTVTAGVIMARYFKPDWPEQNILGQKVWFQLHRMLMSLTVLLTLVAFVLPFIYRGGWSKRAG----IHPYLGCVVMALTLIQPVMALFRPAPDAARRYIFNWMHFGTGTAAQIVAVVTIFLGIH-----QQALFLPSP-WATGLLAFTVIWFVLADLVLEVH 505          
BLAST of Cytochrome b561/ferric reductase transmembrane,domain-containing protein vs. Ensembl Zebrafish
Match: frrs1a (ferric-chelate reductase 1a [Source:ZFIN;Acc:ZDB-GENE-070705-45])

HSP 1 Score: 123.25 bits (308), Expect = 1.853e-29
Identity = 105/334 (31.44%), Postives = 149/334 (44.61%), Query Frame = 2
Query:  170 ESMSFQTCESEKACFKSSKYC--TYDSCDFAISWKPFSYMNNDYIEFEMVGTVFGDNSYMLVGFSDDTSLGNDGFVSCHVESKKVKVVAGFYEVGDTPE-SNIKFSNDVSLLVANSDKRYGGVYNEDTKRLTCRFLRQT-RPQNANNQYKDLSLGNEYYLFTARGNEASQYGY-GPPTAGSLIFSKHPIDFSRGSFHGVIGESSRVDSSFAKTHGILMVIAWVFCSSVGVILARYYKEMWPYTGIAKEMVWFQFHRSLQGTCVLLTTVAFILIFASVGGYSKLDRSPYVAHPILGIIVFILAFLNPLVALCRCRPNSKDRPWFNWFHFFIGSIA 1156
            +  S   C  +K C      C  + D+  F +++      +   + FE+ G   G   Y+    S D  +G+D    C  +  +V V A +      P+ S+     DV   V++      G+       + C+F R    PQ+        SL N YYLF A G  +++YG     T   LI S H +         VI   SR      K HG LM+IAW+   S G ++A Y+K  WP   +  + +WFQ HR L    VLLT+V FI+ F   G +S        AHP LG  V ILAF  PL+A  R  P+S  R  FNW H+ +G+ A
Sbjct:  196 QPFSSDGCGRQKTCLLDPVGCNPSVDTNCFYLAYS----TSGQTVSFELSGPAQG---YVSFALSSDKWMGDDDVYLCVYDGGRVSVEAAYTTGRTYPKVSSQSVLMDVGWRVSD------GI-------IQCKFSRSIYTPQDPER----FSLNNSYYLFIAHG--SAEYGMIHRHTRQPLISSHHQVIIGPP----VILTGSR-SPLLMKYHGALMLIAWMLAGSTGTLMAGYFKPDWPEQTLFGQKIWFQVHRMLMSLTVLLTSVGFIVPFIYRGKWSTRAG----AHPYLGCTVMILAFCQPLMAAFRPAPDSPRRWIFNWLHWGVGNAA 494          
BLAST of Cytochrome b561/ferric reductase transmembrane,domain-containing protein vs. Ensembl Zebrafish
Match: wu:fj05g07 (wu:fj05g07 [Source:ZFIN;Acc:ZDB-GENE-030131-7307])

HSP 1 Score: 122.865 bits (307), Expect = 4.124e-29
Identity = 94/348 (27.01%), Postives = 148/348 (42.53%), Query Frame = 2
Query:  179 SFQTCESEKACFKSSKYC---TYDSCDFAISWKPFSYMNNDYIEFEMVGTVFGDNSYMLVGFSDDTSLGNDGFVSCHVESKKVKVVAGFYEVGDTPESNIKFSNDVSLLVANSDKRYGGVYNEDTKRLTCRFLRQTRPQNANNQYKDLSLGNEYYLFTARGNEASQYGYGPPTAGSLIFSKHPIDFSRGSFHGVIGESSRVDSS-----FAKTHGILMVIAWVFCSSVGVILARYYKEMWPYTGIAKEMVWFQFHRSLQGTCVLLTTVAFILIFASVGGYSKLDRSPYVAHPILGIIVFILAFLNPLVALCRCRPNSKDRPWFNWFHFFIGSIAYCLSVPTIMIGMRI 1198
            S   C S K CF     C   T + C F       +  +   ++ EM G   G   Y+ +GFSDD  +GND    C  ++     V   +  G +  + +   N  +++ A ++ +           + C F  +     A+    +    NEY+L  A G+            G + F  H   +   +   ++  S  + S        K HG LM+I+W+   S+G+I+ARY K +    G   +  WF  H SL    V+ T +AFI++F S G +         AHP+LG +V IL+ + P+VA  RC P  + R  FNW H        CL+V  I  G+ +
Sbjct:  186 SIPGCGSTKVCFSEPNNCNPTTSNGCYFVAVQ---TSSDQSEMKIEMFGQADG---YVAIGFSDDKEMGNDDVYICGKDNNGNLQVQHAFNSGKSSPAILSLGNVSNIMTALTNGK-----------INCSFTSRNTISTASRAASN----NEYHLMIAAGSS---------NEGKIQF--HTNKYVSSTKANLLNPSVVITSEEEFPPIVKAHGCLMLISWMATGSIGMIIARYLKGVAKGQGCCGKDFWFVAHVSLMTLSVIATAIAFIIVFVSAGDWVG------GAHPVLGCLVMILSLIQPIVAAFRCEPQHERRFVFNWAHSCNAFAIKCLAVAAIFTGLAL 495          
BLAST of Cytochrome b561/ferric reductase transmembrane,domain-containing protein vs. Ensembl Zebrafish
Match: frrs1l (ferric-chelate reductase 1-like [Source:ZFIN;Acc:ZDB-GENE-120827-1])

HSP 1 Score: 51.9878 bits (123), Expect = 9.241e-7
Identity = 54/192 (28.12%), Postives = 88/192 (45.83%), Query Frame = 2
Query:  161 DALESMSFQTCESEKACFKSSKY-CTYDSCDFAISWKPFSYMNNDYIEFEMVGTVFGDNSYMLVGFSDDTSLGNDGFVSC-HVESKKVKVVAGFYEVGDTPESNIKFSNDVSLLVANSDKRYGGVYNEDTKRLTCRFLRQTRPQNANNQYK--DLSLGNEYYLFTARGNEASQYGYGPPTAGSLIFSKHPID 724
            D    +    C   K C +  K  C  +SCD+ +S   F  +  D +EFEM     G   ++ VGFS D  +G D  + C H ++ +V+ +  FY VG       +++ ++    A  ++   G++  +  R+TCRF    RP +   +    DL L + YYLF           +GP   GS+  ++H ID
Sbjct:   96 DPFARIKVSDCGVTKGCIRYGKPGCDAESCDYFLS---FRRIGTD-VEFEMSADTDG---WVAVGFSSDKKMGGDDVMGCVHDDNGRVR-IHHFYNVG-------QWAKEIKRNPARDEE---GIF--ENNRVTCRF---KRPLHVAREETLVDLHL-SWYYLFA----------WGPAIQGSI--TRHDID 251          
BLAST of Cytochrome b561/ferric reductase transmembrane,domain-containing protein vs. Ensembl Xenopus
Match: FRRS1 (ferric-chelate reductase 1 [Source:NCBI gene;Acc:100497064])

HSP 1 Score: 140.969 bits (354), Expect = 6.054e-35
Identity = 116/416 (27.88%), Postives = 189/416 (45.43%), Query Frame = 2
Query:  191 CESEKACFKSSKYC--TYDSCDFAISWKPFSYMNNDYIEFEMVGTVFGDNSYMLVGFSDDTSLGNDGFVSCHVESKKVKVVAGFYEVGDTPESNIKFSNDVSLLVANSDKRYGGVYNEDTKRLTCRFLRQTRPQNANNQYKDLSLGNEYYLFTARGNEASQYGYGPPTAGSLIFSKHPIDFSRGSFHGVIGESSRVDSSFA----KTHGILMVIAWVFCSSVGVILARYYKEMWPYTGIAKEMVWFQFHRSLQGTCVLLTTVAFILIFASVGGYSKLDRSPYVAHPILGIIVFILAFLNPLVALCRCRPNSKDRPWFNWFHFFIGSIAYCLSVPTIMIGMRISGPGRQLAYLESP--QWILIFFVLFQFAVEIILEIHGCLYYRRNKDKKHTYEMEMEEYQAALIANHAPQTKPIS 1414
            C S K C ++   C   ++   F +S++     +   +  EM G   G   Y+    S D  +G+D    C  E + V++   +      PE            V++ D      +  +   + C F R  +   +  ++    LG  YY+F A G+              L   + P+  +R   + + G    V  S +    K HG +M +AW+   S+GVI+AR++K +WP + +  E +WFQ HR L  T V+LT +AF+L F   G +SK  R+ Y  HP LG+ V IL  L P++A+ R  P +  R  FNW H+  G+ A  ++V  + IGM +     Q   L  P   + ++ FVL+   V+++LE HG    ++ K         MEE Q  ++ N +P    +S
Sbjct:  199 CGSTKFCIRNPVSCDPEHNPKCFFLSFR----KDGQSVLVEMSGPGQG---YISFALSYDHWMGDDDAYLCVKEDQGVQINPAYIRGRSHPE------------VSSPDVLRDVAWRLEDGVIQCSFKRNIQIPASKERF---DLGGSYYIFLADGDAKDGL--------LLRHQRQPLMTNR--MYNISGFPEDVGGSRSPLIIKFHGAMMFVAWMTTVSIGVIIARFFKPVWPTSSLFGEKIWFQIHRCLMITTVILTAIAFVLPFIYRGYFSK--RAGY--HPHLGVTVMILTVLQPVLAVFRPPPQTPRRGIFNWTHWATGTAARIIAVTAMFIGMDL-----QALDLPDPWDTYTMVGFVLWHVFVDLLLEAHGFCLLKKAK--------TMEEDQVGIL-NSSPDEAEVS 564          
BLAST of Cytochrome b561/ferric reductase transmembrane,domain-containing protein vs. Ensembl Xenopus
Match: FRRS1 (ferric-chelate reductase 1 [Source:NCBI gene;Acc:100497064])

HSP 1 Score: 138.658 bits (348), Expect = 1.105e-34
Identity = 113/402 (28.11%), Postives = 184/402 (45.77%), Query Frame = 2
Query:  140 ISLVFVCDALESMSFQTCESEKACFKSSKYCT--YDSCDFAISWKPFSYMNNDYIEFEMVGTVFGDNSYMLVGFSDDTSLGNDGFVSCHVESKKVKVVAGFYEVGDTPESNIKFSNDVSLLVANSDKRYGGVYNEDTKRLTCRFLRQTRPQNANNQYKDLSLGNEYYLFTARGNEASQYGYGPPTAGSLIFSKHPIDFSRGSFHGVIGESSRVDSS----FAKTHGILMVIAWVFCSSVGVILARYYKEMWPYTGIAKEMVWFQFHRSLQGTCVLLTTVAFILIFASVGGYSKLDRSPYVAHPILGIIVFILAFLNPLVALCRCRPNSKDRPWFNWFHFFIGSIAYCLSVPTIMIGMRISGPGRQLAYLESP--QWILIFFVLFQFAVEIILEIHG-CLYYR 1318
            +S +  C  ++  S   C S K C ++   C   ++   F +S++     +   +  EM G   G   Y+    S D  +G+D    C  E + V++   +      PE            V++ D      +  +   + C F R  +   +  ++    LG  YY+F A G+              L   + P+  +R   + + G    V  S      K HG +M +AW+   S+GVI+AR++K +WP + +  E +WFQ HR L  T V+LT +AF+L F   G +SK  R+ Y  HP LG+ V IL  L P++A+ R  P +  R  FNW H+  G+ A  ++V  + IGM +     Q   L  P   + ++ FVL+   V+++LE HG CL  +
Sbjct:  100 VSQLLTCGGIQVSS--GCGSTKFCIRNPVSCDPEHNPKCFFLSFR----KDGQSVLVEMSGPGQG---YISFALSYDHWMGDDDAYLCVKEDQGVQINPAYIRGRSHPE------------VSSPDVLRDVAWRLEDGVIQCSFKRNIQIPASKERF---DLGGSYYIFLADGDAKDGL--------LLRHQRQPLMTNR--MYNISGFPEDVGGSRSPLIIKFHGAMMFVAWMTTVSIGVIIARFFKPVWPTSSLFGEKIWFQIHRCLMITTVILTAIAFVLPFIYRGYFSK--RAGY--HPHLGVTVMILTVLQPVLAVFRPPPQTPRRGIFNWTHWATGTAARIIAVTAMFIGMDL-----QALDLPDPWDTYTMVGFVLWHVFVDLLLEAHGFCLLKK 458          
BLAST of Cytochrome b561/ferric reductase transmembrane,domain-containing protein vs. Ensembl Xenopus
Match: FRRS1 (ferric-chelate reductase 1 [Source:NCBI gene;Acc:100497064])

HSP 1 Score: 140.584 bits (353), Expect = 1.125e-34
Identity = 117/419 (27.92%), Postives = 189/419 (45.11%), Query Frame = 2
Query:  191 CESEKACFKSSKYC--TYDSCDFAISWKPFSYMNNDYIEFEMVGTVFGDNSYMLVGFSDDTSLGNDGFVSCHVESKKVKVVAGFYEVGDTPESNIKFSNDVSLLVANSDKRYGGVYNEDTKRLTCRFLRQTRPQNANNQYKDLSLGNEYYLFTARGNEASQYGYGPPTAGSLIFSKHPIDFSRGSFHGVIGESSRVDSS----FAKTHGILMVIAWVFCSSVGVILARYYKEMWPYTGIAKEMVWFQFHRSLQGTCVLLTTVAFILIFASVGGYSKLDRSPYVAHPILGIIVFILAFLNPLVALCRCRPNSKDRPWFNWFHFFIGSIAYCLSVPTIMIGMRISGPGRQLAYLESP--QWILIFFVLFQFAVEIILEIHG-CLYYRRNKDKKHTYEMEMEEYQAALIANHAPQTKPISPK 1420
            C S K C ++   C   ++   F +S++     +   +  EM G   G   Y+    S D  +G+D    C  E + V++   +      PE            V++ D      +  +   + C F R  +   +  ++    LG  YY+F A G+              L   + P+  +R   + + G    V  S      K HG +M +AW+   S+GVI+AR++K +WP + +  E +WFQ HR L  T V+LT +AF+L F   G +SK  R+ Y  HP LG+ V IL  L P++A+ R  P +  R  FNW H+  G+ A  ++V  + IGM +     Q   L  P   + ++ FVL+   V+++LE HG CL  +    K   +   + +Y   L    + Q+ P S K
Sbjct:  199 CGSTKFCIRNPVSCDPEHNPKCFFLSFR----KDGQSVLVEMSGPGQG---YISFALSYDHWMGDDDAYLCVKEDQGVQINPAYIRGRSHPE------------VSSPDVLRDVAWRLEDGVIQCSFKRNIQIPASKERF---DLGGSYYIFLADGDAKDGL--------LLRHQRQPLMTNR--MYNISGFPEDVGGSRSPLIIKFHGAMMFVAWMTTVSIGVIIARFFKPVWPTSSLFGEKIWFQIHRCLMITTVILTAIAFVLPFIYRGYFSK--RAGY--HPHLGVTVMILTVLQPVLAVFRPPPQTPRRGIFNWTHWATGTAARIIAVTAMFIGMDL-----QALDLPDPWDTYTMVGFVLWHVFVDLLLEAHGFCLLKKEYISKLPCHLQALHQY--GLFIGGSKQSDPQSAK 574          
BLAST of Cytochrome b561/ferric reductase transmembrane,domain-containing protein vs. Ensembl Xenopus
Match: FRRS1 (ferric-chelate reductase 1 [Source:NCBI gene;Acc:100497064])

HSP 1 Score: 139.043 bits (349), Expect = 2.554e-34
Identity = 113/404 (27.97%), Postives = 183/404 (45.30%), Query Frame = 2
Query:  191 CESEKACFKSSKYC--TYDSCDFAISWKPFSYMNNDYIEFEMVGTVFGDNSYMLVGFSDDTSLGNDGFVSCHVESKKVKVVAGFYEVGDTPESNIKFSNDVSLLVANSDKRYGGVYNEDTKRLTCRFLRQTRPQNANNQYKDLSLGNEYYLFTARGNEASQYGYGPPTAGSLIFSKHPIDFSRGSFHGVIGESSRVDSS----FAKTHGILMVIAWVFCSSVGVILARYYKEMWPYTGIAKEMVWFQFHRSLQGTCVLLTTVAFILIFASVGGYSKLDRSPYVAHPILGIIVFILAFLNPLVALCRCRPNSKDRPWFNWFHFFIGSIAYCLSVPTIMIGMRISGPGRQLAYLESP--QWILIFFVLFQFAVEIILEIHG--------CLY--YRRNKDKKHTYE 1348
            C S K C ++   C   ++   F +S++     +   +  EM G   G   Y+    S D  +G+D    C  E + V++   +      PE            V++ D      +  +   + C F R  +   +  ++    LG  YY+F A G+              L   + P+  +R   + + G    V  S      K HG +M +AW+   S+GVI+AR++K +WP + +  E +WFQ HR L  T V+LT +AF+L F   G +SK  R+ Y  HP LG+ V IL  L P++A+ R  P +  R  FNW H+  G+ A  ++V  + IGM +     Q   L  P   + ++ FVL+   V+++LE HG        C Y   R  ++  HT++
Sbjct:  198 CGSTKFCIRNPVSCDPEHNPKCFFLSFR----KDGQSVLVEMSGPGQG---YISFALSYDHWMGDDDAYLCVKEDQGVQINPAYIRGRSHPE------------VSSPDVLRDVAWRLEDGVIQCSFKRNIQIPASKERF---DLGGSYYIFLADGDAKDGL--------LLRHQRQPLMTNR--MYNISGFPEDVGGSRSPLIIKFHGAMMFVAWMTTVSIGVIIARFFKPVWPTSSLFGEKIWFQIHRCLMITTVILTAIAFVLPFIYRGYFSK--RAGY--HPHLGVTVMILTVLQPVLAVFRPPPQTPRRGIFNWTHWATGTAARIIAVTAMFIGMDL-----QALDLPDPWDTYTMVGFVLWHVFVDLLLEAHGFCLLKKGLCFYGAIRAKRNDGHTFK 560          
BLAST of Cytochrome b561/ferric reductase transmembrane,domain-containing protein vs. Ensembl Xenopus
Match: FRRS1 (ferric-chelate reductase 1 [Source:NCBI gene;Acc:100497064])

HSP 1 Score: 137.502 bits (345), Expect = 6.245e-34
Identity = 110/385 (28.57%), Postives = 177/385 (45.97%), Query Frame = 2
Query:  191 CESEKACFKSSKYC--TYDSCDFAISWKPFSYMNNDYIEFEMVGTVFGDNSYMLVGFSDDTSLGNDGFVSCHVESKKVKVVAGFYEVGDTPESNIKFSNDVSLLVANSDKRYGGVYNEDTKRLTCRFLRQTRPQNANNQYKDLSLGNEYYLFTARGNEASQYGYGPPTAGSLIFSKHPIDFSRGSFHGVIGESSRVDSS----FAKTHGILMVIAWVFCSSVGVILARYYKEMWPYTGIAKEMVWFQFHRSLQGTCVLLTTVAFILIFASVGGYSKLDRSPYVAHPILGIIVFILAFLNPLVALCRCRPNSKDRPWFNWFHFFIGSIAYCLSVPTIMIGMRISGPGRQLAYLESP--QWILIFFVLFQFAVEIILEIHG-CLYYR 1318
            C S K C ++   C   ++   F +S++     +   +  EM G   G   Y+    S D  +G+D    C  E + V++   +      PE            V++ D      +  +   + C F R  +   +  ++    LG  YY+F A G+              L   + P+  +R   + + G    V  S      K HG +M +AW+   S+GVI+AR++K +WP + +  E +WFQ HR L  T V+LT +AF+L F   G +SK  R+ Y  HP LG+ V IL  L P++A+ R  P +  R  FNW H+  G+ A  ++V  + IGM +     Q   L  P   + ++ FVL+   V+++LE HG CL  +
Sbjct:  199 CGSTKFCIRNPVSCDPEHNPKCFFLSFR----KDGQSVLVEMSGPGQG---YISFALSYDHWMGDDDAYLCVKEDQGVQINPAYIRGRSHPE------------VSSPDVLRDVAWRLEDGVIQCSFKRNIQIPASKERF---DLGGSYYIFLADGDAKDGL--------LLRHQRQPLMTNR--MYNISGFPEDVGGSRSPLIIKFHGAMMFVAWMTTVSIGVIIARFFKPVWPTSSLFGEKIWFQIHRCLMITTVILTAIAFVLPFIYRGYFSK--RAGY--HPHLGVTVMILTVLQPVLAVFRPPPQTPRRGIFNWTHWATGTAARIIAVTAMFIGMDL-----QALDLPDPWDTYTMVGFVLWHVFVDLLLEAHGFCLLKK 542          
BLAST of Cytochrome b561/ferric reductase transmembrane,domain-containing protein vs. Ensembl Mouse
Match: Frrs1 (ferric-chelate reductase 1 [Source:MGI Symbol;Acc:MGI:108076])

HSP 1 Score: 136.346 bits (342), Expect = 2.030e-33
Identity = 118/427 (27.63%), Postives = 193/427 (45.20%), Query Frame = 2
Query:  191 CESEKACFKSSKYCTYDSCDFAISWKPFSYMNNDYIEFEMVGTVFGDNSYMLVGFSDDTSLGNDGFVSCHVESKKVKVVAGFYEVGDTPESNIKFS-NDVSLLVANSDKRYGGVYNEDTKRLTCRFLRQTRPQNANNQYKDLSLGNEYYLFTARGNEASQYGYGPPTAGSLIFSKHPIDFSRGSFHGVIGESSRVDSSFAKTHGILMVIAWVFCSSVGVILARYYKEMWPYTGIAKEMVWFQFHRSLQGTCVLLTTVAFILIFASVGGYSKLDRSPYVAHPILGIIVFILAFLNPLVALCRCRPNSKDRPWFNWFHFFIGSIAYCLSVPTIMIGMRISGPGRQLAYLESPQ--WILIFFVLFQFAVEIILEIHGCLYYRRNKDKKHTYEMEMEEYQAALIANHAPQTKPISPKQSGRMFKYVMLGMH 1462
            C ++K C +S   C  +  + A  +  F+  +N  +  EM G     + Y+   FS D  +G+D    C  E + V + + +      P  + + +  D++  +A+S              + C F R      A N++    L   YY+F A G       +       + + K+ +  +  S  G     SR  S   K HG LM +AW+   S+GV++AR+++ +W      +E  WFQ HR L     LLT VAF+L F   GG+S   R+ Y  HP LG  V  LA L PL+A  R   +   R  FNW H+ +G+ A  ++V  + +GM + G       L SPQ  + ++ FV++    E+ILEIH    YR ++  +      ++  Q+  +A           +  G +FK V+L ++
Sbjct:  198 CGNKKFCVRSPLNCDPEK-EPACVFLSFT-RDNQSVMVEMSGP---SDGYVSFAFSHDQWMGDDDAYLCIREDQTVDIQSSYLTGRSYPVMDSRGTLEDMAWRLADS-------------VIQCSFRRNITLPEAKNRF---VLNESYYIFFAEGPSHDGRIFRHSQQPLITYEKYNVTDTPKSVGG-----SR-SSPLLKAHGALMFVAWMTTVSIGVLVARFFRSVWSKAFFLREAAWFQVHRMLMVATSLLTCVAFVLPFVYRGGWSW--RAGY--HPYLGCTVMTLAVLQPLLATFRPPLHDPRRQVFNWTHWSVGTAARIIAVAAMFLGMDLPG-----LNLPSPQKTYAMMGFVVWHIGTEVILEIHA---YRLSRKVEILDNDRIQILQSLTVA-----------EAEGHVFKKVVLAVY 574          
BLAST of Cytochrome b561/ferric reductase transmembrane,domain-containing protein vs. Ensembl Mouse
Match: Frrs1 (ferric-chelate reductase 1 [Source:MGI Symbol;Acc:MGI:108076])

HSP 1 Score: 136.346 bits (342), Expect = 2.030e-33
Identity = 118/427 (27.63%), Postives = 193/427 (45.20%), Query Frame = 2
Query:  191 CESEKACFKSSKYCTYDSCDFAISWKPFSYMNNDYIEFEMVGTVFGDNSYMLVGFSDDTSLGNDGFVSCHVESKKVKVVAGFYEVGDTPESNIKFS-NDVSLLVANSDKRYGGVYNEDTKRLTCRFLRQTRPQNANNQYKDLSLGNEYYLFTARGNEASQYGYGPPTAGSLIFSKHPIDFSRGSFHGVIGESSRVDSSFAKTHGILMVIAWVFCSSVGVILARYYKEMWPYTGIAKEMVWFQFHRSLQGTCVLLTTVAFILIFASVGGYSKLDRSPYVAHPILGIIVFILAFLNPLVALCRCRPNSKDRPWFNWFHFFIGSIAYCLSVPTIMIGMRISGPGRQLAYLESPQ--WILIFFVLFQFAVEIILEIHGCLYYRRNKDKKHTYEMEMEEYQAALIANHAPQTKPISPKQSGRMFKYVMLGMH 1462
            C ++K C +S   C  +  + A  +  F+  +N  +  EM G     + Y+   FS D  +G+D    C  E + V + + +      P  + + +  D++  +A+S              + C F R      A N++    L   YY+F A G       +       + + K+ +  +  S  G     SR  S   K HG LM +AW+   S+GV++AR+++ +W      +E  WFQ HR L     LLT VAF+L F   GG+S   R+ Y  HP LG  V  LA L PL+A  R   +   R  FNW H+ +G+ A  ++V  + +GM + G       L SPQ  + ++ FV++    E+ILEIH    YR ++  +      ++  Q+  +A           +  G +FK V+L ++
Sbjct:  198 CGNKKFCVRSPLNCDPEK-EPACVFLSFT-RDNQSVMVEMSGP---SDGYVSFAFSHDQWMGDDDAYLCIREDQTVDIQSSYLTGRSYPVMDSRGTLEDMAWRLADS-------------VIQCSFRRNITLPEAKNRF---VLNESYYIFFAEGPSHDGRIFRHSQQPLITYEKYNVTDTPKSVGG-----SR-SSPLLKAHGALMFVAWMTTVSIGVLVARFFRSVWSKAFFLREAAWFQVHRMLMVATSLLTCVAFVLPFVYRGGWSW--RAGY--HPYLGCTVMTLAVLQPLLATFRPPLHDPRRQVFNWTHWSVGTAARIIAVAAMFLGMDLPG-----LNLPSPQKTYAMMGFVVWHIGTEVILEIHA---YRLSRKVEILDNDRIQILQSLTVA-----------EAEGHVFKKVVLAVY 574          
BLAST of Cytochrome b561/ferric reductase transmembrane,domain-containing protein vs. Ensembl Mouse
Match: Frrs1 (ferric-chelate reductase 1 [Source:MGI Symbol;Acc:MGI:108076])

HSP 1 Score: 69.707 bits (169), Expect = 6.679e-14
Identity = 38/86 (44.19%), Postives = 50/86 (58.14%), Query Frame = 2
Query:  833 SVGVILARYYKEMWPYTGIAKEMVWFQFHRSLQGTCVLLTTVAFILIFASVGGYSKLDRSPYVAHPILGIIVFILAFLNPLVALCR 1090
            S+GV++AR+++ +W      +E  WFQ HR L     LLT VAF+L F   GG+S   R+ Y  HP LG  V  LA L PL+A  R
Sbjct:    2 SIGVLVARFFRSVWSKAFFLREAAWFQVHRMLMVATSLLTCVAFVLPFVYRGGWSW--RAGY--HPYLGCTVMTLAVLQPLLATFR 83          
BLAST of Cytochrome b561/ferric reductase transmembrane,domain-containing protein vs. Ensembl Mouse
Match: Frrs1l (ferric-chelate reductase 1 like [Source:MGI Symbol;Acc:MGI:2442704])

HSP 1 Score: 56.6102 bits (135), Expect = 2.851e-8
Identity = 62/233 (26.61%), Postives = 105/233 (45.06%), Query Frame = 2
Query:  161 DALESMSFQTCESEKACFKSSKY-CTYDSCDFAISWKPFSYMNNDYIEFEMVGTVFGDNSYMLVGFSDDTSLGNDGFVSC-HVESKKVKVVAGFYEVGDTPESNIKFSNDVSLLVANSDKRYGGVYNEDTKRLTCRFLRQTRPQNA--NNQYKDLSLGNEYYLFTARGNEASQYGYGPPTAGSLIFSKHPIDFSRGSFHGV-------IGESSRVDSSFAKTHGILMVIAWVF 826
            D    +  + C   K CF+  K  C  ++CD+ +S++    M    +EFE+     G   ++ VGFS D  +G D  ++C H ++ +V+ +  FY VG       +++ +V    A  ++   GV+  +  R+TCRF    RP N   +    DL L + YYLF           +GP   G++  ++H ID    S   V       I   S    +F+    +L+++A  F
Sbjct:   90 DPFAKIKVEDCGRTKGCFRYGKPGCNAETCDYFLSYR----MIGADVEFELSADTDG---WVAVGFSSDKKMGGDDVMACVHDDNGRVR-IQHFYNVG-------QWAKEVQRNPARDEE---GVF--ENNRVTCRF---KRPVNVPRDETIVDLHL-SWYYLFA----------WGPAIQGAI--TRHDIDSPPASERVVSIYKYEDIFMPSAAYQTFSSPFCLLLIVALTF 286          
BLAST of Cytochrome b561/ferric reductase transmembrane,domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8MSU3|FRRS1_DROME (Putative ferric-chelate reductase 1 homolog OS=Drosophila melanogaster OX=7227 GN=CG8399 PE=2 SV=1)

HSP 1 Score: 145.591 bits (366), Expect = 1.518e-35
Identity = 114/404 (28.22%), Postives = 186/404 (46.04%), Query Frame = 2
Query:  182 FQTCESEKACFKSSKYCTYDSCDFAISWKPFSYMNNDYIEFEMVGTVFGDNSYMLVGFSDDTSLGNDGFVSCHVESKKVKVVAGFYEVGDTPESNIKFS-NDVSLLVANSDKRYGGVYNEDTKRLTCRFLRQTRPQNANNQYKDLSLGNEYYLFTARGNEASQYGYGPPTAGSLIFSKHPIDFSRGSFHGVIGESSRVDSSFAKTHGILMVIAWVFCSSVGVILARYYKEMWPYTGIAKEMVWFQFHRSLQGTCVLLTTVAFILIFASVGGYSKLDRSPYVAHPILGIIVFILAFLNPLVALCRCRPNSKDRPWFNWFHFFIGSIAYCLSVPTIMIGMRISGPGRQLAYLESPQWILIFFVLFQFAVEIILEIHGCLYYRRNKDKKHTYEM-EMEEYQAALIAN 1387
            +  C   K CF     C       +I+      +  D  EFE+      + +Y+ VG SDD  +G+D    C  E+ +V + +       +P S ++ + N  S  + ++    G +Y        CR  R     N   +  DL  G +Y+L  A G+   +   G    G L  S  PI+ +       + + S       + HG  M+ AW+  +S+G+I ARY+K+ W  +       WF +HR L  T   LT  A++LI+       +L ++ + AH I+G+I  IL F+ P+ AL R  PN K RP+FNW H+  G++A+ L + TI   +++  P  +L   E   WIL+ FV+    V +I  I G    R    + +T++M +M  +Q   + N
Sbjct:  226 YNGCGQSKNCFGFPDGCVATKSCTSIT---VVTVRGDVFEFEIQSGKGTNAAYVAVGLSDDAKMGDDLTTECVPENGRVNLYSSLTSA--SPYSAVRSNVNQNSARLLDASIVDGVIY--------CRVQRDAV-TNVQGRTFDLRNG-KYHLLVASGSSLKENSVGYHDIGRLP-SAQPINLAE------VQDLSGSSRLLIQLHGAFMIAAWIGTTSLGIIFARYFKQTWVGSQSCGTDQWFAWHRLLMVTTWSLTVAAYVLIWV------ELKQAVWHAHSIIGLITVILCFIQPIGALFRPGPNDKKRPYFNWGHWLGGNLAHILGIVTIFFSVKL--PKAELP--EWMDWILVSFVVVHVLVHLIFSIGGMASERHLSQRANTFQMGDMSHHQQHAMRN 597          
BLAST of Cytochrome b561/ferric reductase transmembrane,domain-containing protein vs. UniProt/SwissProt
Match: sp|Q6INU7|FRRS1_XENLA (Putative ferric-chelate reductase 1 OS=Xenopus laevis OX=8355 GN=frrs1 PE=2 SV=1)

HSP 1 Score: 139.428 bits (350), Expect = 1.204e-33
Identity = 124/430 (28.84%), Postives = 196/430 (45.58%), Query Frame = 2
Query:  191 CESEKACFKSSKYC--TYDSCDFAISWKPFSYMNNDYIEFEMVGTVFGDNSYMLVGFSDDTSLGNDGFVSCHVESKKVKVVAGFYEVGDTPE-SNIKFSNDVSLLVANSDKRYGGVYNEDTKRLTCRFLRQTRPQNANNQYKDLSLGNEYYLFTARGNEASQYGYGPPTAGSLIFSKHPI-DFSRGSFHGVIGESSRVDSSFAKTHGILMVIAWVFCSSVGVILARYYKEMWPYTGIAKEMVWFQFHRSLQGTCVLLTTVAFILIFASVGGYSKLDRSPYVAHPILGIIVFILAFLNPLVALCRCRPNSKDRPWFNWFHFFIGSIAYCLSVPTIMIGMRISGPGRQLAYLESP--QWILIFFVLFQFAVEIILEIHGCLYYRRNKDKKHTYEMEMEEYQAALIANHAPQTKPISPKQSGRMFKYVMLGMH 1462
            C S K C ++   C   ++   F +S++     +   +  EM G   G   Y+    S D  +G+D    C  E   V++   +      PE S++    DV+  + +      GV       + C F R  +      ++    LG  Y++F A G+      Y       +   K+ I DF       V G  S +     K HG +M IAW+   S+GVI+AR++K +WP + +  E +WFQ HR L  T V LT VAF+L F   G +SK  R+ Y  HP LG+ V IL  L P++A+ R  P +  R  FNW H+  G+ A  ++V  + +GM +     Q   L  P   + +I FVL+   V+++LE HG    ++ K         MEE Q  ++ N +P       +  G  FK +++ ++
Sbjct:  197 CGSSKFCIRNPVSCDPEHNPECFFLSFR----KDGQSVLVEMSGPGQG---YISFALSHDQWMGDDDAYLCVKEDDGVQINPAYIRGRSHPEVSSMDVLRDVAWRLED------GV-------IQCSFRRNIQIPIPKERF---DLGRSYFIFLADGDAKDGLLYRHHRQPLMTNRKYCITDFPED----VGGSRSPL---IIKLHGAMMFIAWMTTVSIGVIIARFFKPVWPTSSLFGEKIWFQIHRCLMITTVFLTVVAFVLPFIYRGYFSK--RAGY--HPHLGVTVMILTVLQPVLAVFRPPPQTHRRGIFNWTHWATGTAARIIAVAAMFLGMDL-----QALDLPDPWDTYTMIGFVLWHVFVDLLLEAHGFCLLKKAK--------TMEEDQIGIL-NSSPD------EAEGHTFKKIVMTVY 572          
BLAST of Cytochrome b561/ferric reductase transmembrane,domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8K385|FRRS1_MOUSE (Ferric-chelate reductase 1 OS=Mus musculus OX=10090 GN=FRRS1 PE=1 SV=1)

HSP 1 Score: 134.806 bits (338), Expect = 4.186e-32
Identity = 119/427 (27.87%), Postives = 193/427 (45.20%), Query Frame = 2
Query:  191 CESEKACFKSSKYCTYDSCDFAISWKPFSYMNNDYIEFEMVGTVFGDNSYMLVGFSDDTSLGNDGFVSCHVESKKVKVVAGFYEVGDTPESNIKFS-NDVSLLVANSDKRYGGVYNEDTKRLTCRFLRQTRPQNANNQYKDLSLGNEYYLFTARGNEASQYGYGPPTAGSLIFSKHPIDFSRGSFHGVIGESSRVDSSFAKTHGILMVIAWVFCSSVGVILARYYKEMWPYTGIAKEMVWFQFHRSLQGTCVLLTTVAFILIFASVGGYSKLDRSPYVAHPILGIIVFILAFLNPLVALCRCRPNSKDRPWFNWFHFFIGSIAYCLSVPTIMIGMRISGPGRQLAYLESPQ--WILIFFVLFQFAVEIILEIHGCLYYRRNKDKKHTYEMEMEEYQAALIANHAPQTKPISPKQSGRMFKYVMLGMH 1462
            C ++K C +S   C  +  + A  +  F+  +N  +  EM G     + Y+   FS D  +G+D    C  E + V +   +      P  + + +  D++  +A+      GV       + C F R      A N++    L   YY+F A G       +       + + K+ +  +  S  G     SR  S   K HG LM +AW+   S+GV++AR+++ +W      +E  WFQ HR L     LLT VAF+L F   GG+S   R+ Y  HP LG  V  LA L PL+A  R   +   R  FNW H+ +G+ A  ++V  + +GM + G       L SPQ  + ++ FV++    E+ILEIH    YR ++  +      ++  Q+  +A           +  G +FK V+L ++
Sbjct:  198 CGNKKFCVRSPLNCDPEK-EPACVFLSFT-RDNQSVMVEMSGP---SDGYVSFAFSHDQWMGDDDAYLCIREDQTVDIQPSYLTGRSYPVMDSRGTLEDMAWRLAD------GV-------IQCSFRRNITLPEAKNRF---VLNESYYIFFAEGPSHDGRIFRHSQQPLITYEKYNVTDTPKSVGG-----SR-SSPLLKAHGALMFVAWMTTVSIGVLVARFFRSVWSKAFFLREAAWFQVHRMLMVATSLLTCVAFVLPFVYRGGWSW--RAGY--HPYLGCTVMTLAVLQPLLATFRPPLHDPRRQVFNWTHWSVGTAARIIAVAAMFLGMDLPG-----LNLPSPQKTYAMMGFVVWHIGTEVILEIHA---YRLSRKVEILDNDRIQILQSLTVA-----------EAEGHVFKKVVLAVY 574          
BLAST of Cytochrome b561/ferric reductase transmembrane,domain-containing protein vs. UniProt/SwissProt
Match: sp|Q6ZNA5|FRRS1_HUMAN (Ferric-chelate reductase 1 OS=Homo sapiens OX=9606 GN=FRRS1 PE=2 SV=2)

HSP 1 Score: 126.716 bits (317), Expect = 2.208e-29
Identity = 113/427 (26.46%), Postives = 185/427 (43.33%), Query Frame = 2
Query:  128 LVFIISLVFVCDALESMSFQTCESEKACFKSSKYCTYD---SCDFAISWKPFSYMNNDY-IEFEMVGTVFGDNSYMLVGFSDDTSLGNDGFVSCHVESKKVKVVAGFYEVGDTPESNIKFS-NDVSLLVANSDKRYGGVYNEDTKRLTCRFLRQTRPQNANNQYKDLSLGNEYYLFTARGNEASQYGYGPPTAGSLIFSKHPIDFSRGSFHGVIGESSRVDSSFAKTHGILMVIAWVFCSSVGVILARYYKEMWPYTGIAKEMVWFQFHRSLQGTCVLLTTVAFILIFASVGGYSKLDRSPYVAHPILGIIVFILAFLNPLVALCRCRPNSKDRPWFNWFHFFIGSIAYCLSVPTIMIGMRISGPGRQLAYLESPQWILIFFVLFQFAVEIILEIHGCLYYRRNKDKKHTYEMEMEEYQAALIANHA 1393
            +V + +L  V    +  S   C ++K C +S   C  +   SC F       S+  +D  +  EM G   G   Y+    S D  +G+D    C  E + V +          P  + + +  D++  +A+      GV       + C F R        N++    L   YY+F A G       Y       + + K+ +  S  +    IG S  V     K HG LM +AW+   S+GV++AR++K +W    +  E  WFQ HR L  T  +LT +AF++ F   GG+S+   + Y  HP LG IV  LA L PL+A+ R   +   R  FNW H+ +G+ A  ++V  + +GM + G     ++     + +  FV +    E++LE+H     R+ +         ++ + A     HA
Sbjct:  177 VVPLPTLPPVSHLTKPFSASDCGNKKFCIRSPLNCDPEKEASCVF------LSFTRDDQSVMVEMSGPSKG---YLSFALSHDQWMGDDDAYLCIHEDQTVYIQPSHLTGRSHPVMDSRDTLEDMAWRLAD------GV-------MQCSFRRNITLPGVKNRF---DLNTSYYIFLADGAANDGRIYKHSQQPLITYEKYDVTDSPKN----IGGSHSV--LLLKVHGALMFVAWMTTVSIGVLVARFFKPVWSKAFLLGEAAWFQVHRMLMFTTTVLTCIAFVMPFIYRGGWSR--HAGY--HPYLGCIVMTLAVLQPLLAVFRPPLHDPRRQMFNWTHWSMGTAARIIAVAAMFLGMDLPGLNLPDSW---KTYAMTGFVAWHVGTEVVLEVHAYRLSRKVEILDDDRIQILQSFTAVETEGHA 565          
BLAST of Cytochrome b561/ferric reductase transmembrane,domain-containing protein vs. UniProt/SwissProt
Match: sp|A4QP81|FRRS1_DANRE (Putative ferric-chelate reductase 1 OS=Danio rerio OX=7955 GN=frrs1 PE=2 SV=1)

HSP 1 Score: 108.227 bits (269), Expect = 2.328e-23
Identity = 95/348 (27.30%), Postives = 151/348 (43.39%), Query Frame = 2
Query:  179 SFQTCESEKACFKSSKYC---TYDSCDFAISWKPFSYMNNDYIEFEMVGTVFGDNSYMLVGFSDDTSLGNDGFVSCHVESKKVKVVAGFYEVGDTPESNIKFSNDVSLLVANSDKRYGGVYNEDTKRLTCRFLRQTRPQNANNQYKDLSLGNEYYLFTARGNEASQYGYGPPTAGSLIFSKHPIDFSRGSFHGVIGESSRVDSS-----FAKTHGILMVIAWVFCSSVGVILARYYKEMWPYTGIAKEMVWFQFHRSLQGTCVLLTTVAFILIFASVGGYSKLDRSPYVAHPILGIIVFILAFLNPLVALCRCRPNSKDRPWFNWFHFFIGSIAYCLSVPTIMIGMRI 1198
            S   C + K CF     C   T   C F ++ +  S  +   +  EM G   G   Y+ +GFSDD  +GND    C  ++     V   +  G +  + +   N   +L A ++             + C F+ +     A+      +  NEYYL  A G+ +          G++ F  H   +   +   ++  S  + S        K HG LM+I+W+   S+G+I+ARY K +    G   +  WF  H SL    ++ T +AFI++F S G ++        AHP+LG +V IL+ + P+VA  RC P  + R  FNW H        CL+V  I  G+ +
Sbjct:  189 SIPGCGTTKVCFSQPNNCDPTTSTGCYF-VAVQASS--DQSEMRIEMFGPADG---YVAIGFSDDQQMGNDDVYICGKDNNGNLQVQHAFNSGRSRPAILSLGNVTDILTAVTNGN-----------INCSFISRNTISTASRA----ATTNEYYLMIAAGSSSQ---------GNIQF--HTNKYVTSTKVNLLNPSVVITSEEEFPPMVKAHGCLMLISWMATGSIGMIIARYLKGVAKGQGCFGKDFWFVAHVSLMTLSIIATAIAFIIVFVSAGDWAG------GAHPVLGCLVMILSLIQPIVAAFRCEPQHERRFVFNWAHSCNAFAIKCLAVAAIFTGLAL 498          
BLAST of Cytochrome b561/ferric reductase transmembrane,domain-containing protein vs. TrEMBL
Match: A0A3Q0KUG7 (Ceramidase OS=Schistosoma mansoni OX=6183 PE=4 SV=1)

HSP 1 Score: 397.897 bits (1021), Expect = 3.692e-130
Identity = 198/416 (47.60%), Postives = 270/416 (64.90%), Query Frame = 2
Query:  230 CTYDSCDFAISWKPFSYMNNDYIEFEMVGTVFGDNSYMLVGFSDDTSLGNDGFVSCHVES--KKVKVVAGFYEVGDTPESNIKFSNDVSLLVANSDKRYGGVYNEDTKRLTCRFLRQTRPQNANNQYKDLSLGNEYYLFTARGNEASQYGYGPPTAGSLIFSKHPIDFSR---GSFHGVIGESSRVDSSFAKTHGILMVIAWVFCSSVGVILARYYKEMWPYTGIAKEMVWFQFHRSLQGTCVLLTTVAFILIFASVGGYSKLDRSPYVAHPILGIIVFILAFLNPLVALCRCRPNSKDRPWFNWFHFFIGSIAYCLSVPTIMIGMRISGPGRQLAYLESPQWILIFFVLFQFAVEIILEIHGCLYYRRNKDKKHTYEMEMEEYQAALIANHAPQTKPISPKQSGRMFKYVMLGMH 1462
            CT  SC F ++WK  S  + +Y+EFE+ G +     ++ + FS D  +G+DG V C+ +S    V + AG+ ++     +N     D  LL+ + +   GG +N     L CRF R+ RP +  +Q  DL+  N Y+L   RG E  + G+G P AG    S+ P+  +    GS  G+IG  S    + AKTHG LMV+AWV C+S+G+ILARYYK++WP +G+  E VWFQ HR LQG CV LT ++ ILIF    GYS+    PY  HPILG+IVF LA +NP++ALCRC P  + RPWFNW HFFIG+ AY LSVPT+M+G+R+   G QL ++  P WILIFFV+FQF +EIILEIHGC YYRRNK+K+ TY +E+++YQAA   N+A Q +P  P+ SGRMFKY ++G+H
Sbjct:    2 CTESSCAFLVTWKLVSVKSENYVEFELRGNIQKVTGFIALAFSKDQRVGDDGVVGCYYQSSTNTVNIRAGYNDIAGK-TTNFYNGPDEELLITDGEN-LGGTFNAMDGTLQCRFRRRVRPLDTVHQLMDLTSPNAYHLIVTRGVERKKDGFGRPFAGGESVSQRPVVITSPIYGSMTGIIGRGS----AIAKTHGCLMVLAWVLCASIGIILARYYKDVWPNSGLLGERVWFQSHRILQGICVGLTCISIILIFIYCEGYSQATAYPYYIHPILGLIVFSLALINPIIALCRCNPAHEYRPWFNWIHFFIGTFAYILSVPTMMLGLRMPAAGLQLQFINYPLWILIFFVIFQFMIEIILEIHGCFYYRRNKNKRRTYVLEIDQYQAAKRLNNARQPRPPEPEPSGRMFKYFIIGLH 411          
BLAST of Cytochrome b561/ferric reductase transmembrane,domain-containing protein vs. TrEMBL
Match: A0A0X3PKR9 (Ferric-chelate reductase 1 OS=Schistocephalus solidus OX=70667 GN=FRRS1 PE=4 SV=1)

HSP 1 Score: 392.889 bits (1008), Expect = 1.258e-127
Identity = 198/451 (43.90%), Postives = 270/451 (59.87%), Query Frame = 2
Query:  125 ILVFIISLVFVCDA---LESMSFQTCESEKACFKSSKYCTYDSCDFAISWKPFSYMNNDYIEFEMVGTVFGDNSYMLVGFSDDTSLGNDGFVSCHVESKKVKVV--AGFYEVGDTPESNIKFSNDVSLLVANSDKRYGGVYNEDTKRLTCRFLRQTRPQNANNQYKDLSLGNEYYLFTARGNEASQYGYGPPTAGSLIFSKHPIDFSRGSFHGVIGESSRVDSSFAKTHGILMVIAWVFCSSVGVILARYYKEMWPYTGIAKEMVWFQFHRSLQGTCVLLTTVAFILIFASVGGYSKLDRSPYVAHPILGIIVFILAFLNPLVALCRCRPNSKDRPWFNWFHFFIGSIAYCLSVPTIMIGMRISGPGRQLAYLESPQWILIFFVLFQFAVEIILEIHGCLYYRRNKDKKHTYEMEMEEYQAALIANHAPQTKPISPKQSGRMFKYVMLGMH 1462
            +L  I + +FV  A    + +    C   K C + S  C  D C++A +W+     + DYIEFE++G V   + ++ + FS D   G DGFV C+ ++  +K V  AG+          +   +D +LLV   +   GG Y+E  ++L CRF R+  P   +++ KDL+  N Y+L   RG++     +G    G    SK     +    +GV  E     S  AK HG +MV+AWVFCSSVGVIL+RYYK+MWP +G+  E VWFQ HR L G CV LT +A IL FA   GYS L   P   HPILG+IV  LAF+NPL + CRC PNSK RP+FNW HFFIG+ A+CLS+PT+M+G+R+   G  L  L  P WILIFFV+FQF VEI LEIHGC++YRRNK+K+  Y  E+E Y+ A  +  AP  +P  P+ SGR+FKY ++ +H
Sbjct:    1 MLSLIFAFIFVSSARGAFQEIDLTNCGVTKGCLRPS-VCADDHCEYAATWRLIDQDSVDYIEFELLGDVKSSDGFVTLVFSKDRHFGGDGFVGCYYDTYNMKTVVRAGYRPEASISNQLVSVDDDPTLLVTEGEN-LGGEYSEVKQQLQCRFRRRVTPVRLSDRLKDLAPPNAYFLMIQRGSDPLGSAFGSLYPGGEAVSKENAVVT-SPLYGVRIEDQMRASGVAKAHGCMMVLAWVFCSSVGVILSRYYKDMWPNSGLLGERVWFQLHRILMGVCVGLTCIAVILAFAFCYGYSTLSSYPDYIHPILGLIVLCLAFINPLTSFCRCHPNSKHRPYFNWIHFFIGTFAHCLSIPTMMLGLRLPAAGVHLRTLNYPLWILIFFVIFQFIVEITLEIHGCIFYRRNKNKRMAYLNELENYRIATQSGGAPTPRPAEPEPSGRIFKYFVISLH 448          
BLAST of Cytochrome b561/ferric reductase transmembrane,domain-containing protein vs. TrEMBL
Match: A0A094ZJD1 (Ferric-chelate reductase 1 OS=Schistosoma haematobium OX=6185 GN=MS3_02889 PE=4 SV=1)

HSP 1 Score: 378.637 bits (971), Expect = 4.493e-122
Identity = 207/454 (45.59%), Postives = 284/454 (62.56%), Query Frame = 2
Query:  125 ILVFI---ISLVFVCDALESMSFQTCESEKACFKSSKYCTYDSCDFAISWKPFSYMNNDYIEFEMVGTVFGDNSYMLVGFSDDTSLGNDGFVSCHVES--KKVKVVAGFYEVGDTPESNIKFSNDVSLLVANSDKRYGGVYNEDTKRLTCRFLRQTRPQNANNQYKDLSLGNEYYLFTARGNEASQYGYGPPTAGSLIFSKHPIDFSR---GSFHGVIGESSRVDSSFAKTHGILMVIAWVFCSSVGVILARYYKEMWPYTGIAKEMVWFQFHRSLQGTCVLLTTVAFILIFASVGGYSKLDRSPYVAHPILGIIVFILAFLNPLVALCRCRPNSKDRPWFNWFHFFIGSIAYCLSVPTIMIGMRISGPGRQLAYLESPQWILIFFVLFQFAVEIILEIHGCLYYRRNKDKKHTYEMEMEEYQAALIANHAPQTKPISPKQSGRMFKYVMLGMH 1462
            + VFI   +S  F       ++   C S K C + +  CT  SC F ++WK  S  + +Y+EFE+ G V     ++ + FS D  +G+DG V C+ +S    V + AG+ ++     +N     D  LL+ + +   GG +N     L CRF R+ RP +  +Q  DL+  N Y+L   RG E  + G+G P AG    S+ P+  +    GS  G+IG  S +    AKTHG LMV+AWV C+S+G+ILARYYK++WP +G+  E VWFQ HR LQG CV LT ++ ILIF    GYS+    PY  HPILG+IVF LA +NP++ALCRC P  + RPWFNW HFFIG+ AY LSVPT+M+G+R+   G QL ++  P WILIFFV+FQF +EI LEIHGC YYRRNK+K+ TY +E+++YQAA   N+A Q +P  P+ SGRMFKY ++G+H
Sbjct:    5 VTVFINLALSATFANAIFPDITLHECASTKGCLRPAM-CTESSCAFLVTWKLVSVKSENYVEFELRGNVQKVTGFIALAFSKDQRVGDDGVVGCYYQSSTNTVNIRAGYNDIAGK-TTNFYNGPDEELLITDGEN-LGGTFNAMDGTLQCRFRRRVRPLDTVHQLMDLTSPNAYHLIVTRGVERKKDGFGRPFAGGESVSQRPVVITSPIYGSMTGIIGRGSAI----AKTHGCLMVLAWVLCASIGIILARYYKDVWPNSGLLGERVWFQSHRILQGICVGLTCISIILIFIYCEGYSQATAYPYYIHPILGLIVFSLALINPIIALCRCNPAHEYRPWFNWIHFFIGTFAYVLSVPTMMLGLRMPAAGLQLQFINYPLWILIFFVIFQFIIEITLEIHGCFYYRRNKNKRRTYVLEIDQYQAAKRLNNARQPRPPEPEPSGRMFKYFIIGLH 451          
BLAST of Cytochrome b561/ferric reductase transmembrane,domain-containing protein vs. TrEMBL
Match: A0A3R7FXV9 (Ferric-chelate reductase 1 OS=Clonorchis sinensis OX=79923 GN=FRRS1 PE=4 SV=1)

HSP 1 Score: 373.244 bits (957), Expect = 5.775e-120
Identity = 192/432 (44.44%), Postives = 265/432 (61.34%), Query Frame = 2
Query:  176 MSFQTCESEKACFKSSKYCTYDSCDFAISWKPFSYMNNDYIEFEMVGTVFGDNSYMLVGFSDDTSLGNDGFVSC--HVESKKVKVVAGFYEVGDTPESNIKFSN-DVSLLVANSDKRYGGVYNEDTKRLTCRFLRQTRPQNANNQYKDLSLGNEYYLFTARGNEASQYGYGPPTAGSLIFSKHPIDFSRGSFHGVIGESSRVDSSFAKTHGILMVIAWVFCSSVGVILARYYKEMWPYTGIAKEMVWFQFHRSLQGTCVLLTTVAFILIFASVGGYSKLDRSPYVAHPILGIIVFILAFLNPLVALCRCRPNSKDRPWFNWFHFFIGSIAYCLSVPTIMIGMRISGPGRQLAYLESPQWILIFFVLFQFAVEIILEIHGCLYYRRNKDKKHTYEMEMEEYQAALIANHAPQTKPISPKQSGRMFKYVMLGMH 1462
            +S   C + K C      CT   C+F  +WK  ++   DY+EFE+ G +     ++ + FS+D  +   G V C  H  +  V+  AG+    ++ + N  ++  D  LL++  D   GG YN   K L CRF R+ RP++   Q KDLS  N YYL   RGN+    G+  P AG      + +  +    +G +   S   S+  KTHG LMV+AWV C+S+GVILARYYKE+WP +G+  E VWFQ HR LQ +CV+LT +A IL F    GYS++   P+  HPILG+IVF LA LNPL+  CRC+ +  DRPWFNW HFFIG+ A+ LSVPT+M+G+R+   G QL +L  P WILIFFV+FQF +E+ILEIHGC+YY RNK+K+  Y  E+ +Y A +     P++KP  P+ SGRMFKY ++G+H
Sbjct:   25 VSVVGCGTIKGCL-FPPICTDSYCEFMTTWKLVTHNAEDYVEFELKGKLNDPGGFLSLAFSEDKKISTAGVVGCYHHAATGAVRARAGY----NSGKMNTFYTGPDTELLISEGDN-LGGTYNPADKVLQCRFRRRVRPRDMVLQLKDLSEPNAYYLTITRGNDVLPSGFSRPFAGGEATYDNSVLIT-SPIYGSMTVISEQGSALMKTHGCLMVLAWVLCASIGVILARYYKELWPNSGLLGERVWFQSHRILQSSCVILTCIAIILAFIYCEGYSRVSTFPHYVHPILGLIVFCLALLNPLITFCRCKVDHPDRPWFNWIHFFIGTFAHVLSVPTMMLGLRMPAAGFQLQFLNYPLWILIFFVIFQFCIELILEIHGCMYYNRNKNKRREYTRELTQYHAGVRTALGPRSKPPEPEPSGRMFKYFIIGLH 449          
BLAST of Cytochrome b561/ferric reductase transmembrane,domain-containing protein vs. TrEMBL
Match: A0A074ZBH1 (Uncharacterized protein OS=Opisthorchis viverrini OX=6198 GN=T265_09068 PE=4 SV=1)

HSP 1 Score: 370.933 bits (951), Expect = 4.483e-119
Identity = 195/438 (44.52%), Postives = 267/438 (60.96%), Query Frame = 2
Query:  176 MSFQTCESEKACFKSSKYCTYDSCDFAISWKPFSYMNNDYIEFEMVGTVFGDNSYMLVGFSDDTSLGNDGFVSC--HVESKKVKVVAGFYEVGDTPESNIKFSN-DVSLLVANSDKRYGGVYNEDTKRLTCRFLRQTRPQNANNQYKDLSLGNEYYLFTARGNEASQYGYGPPTAG------SLIFSKHPIDFSRGSFHGVIGESSRVDSSFAKTHGILMVIAWVFCSSVGVILARYYKEMWPYTGIAKEMVWFQFHRSLQGTCVLLTTVAFILIFASVGGYSKLDRSPYVAHPILGIIVFILAFLNPLVALCRCRPNSKDRPWFNWFHFFIGSIAYCLSVPTIMIGMRISGPGRQLAYLESPQWILIFFVLFQFAVEIILEIHGCLYYRRNKDKKHTYEMEMEEYQAALIANHAPQTKPISPKQSGRMFKYVMLGMH 1462
            +S   C + K C      CT   C+F  +WK  ++   DY+EFE+ G +     ++ + FS+D  +   G V C  H  +  V+  AG+    ++ ++N  ++  D  LL++  D   GG YN   K L CRF R+ RP++   Q KDLS  N YYL   RGN+    G+  P AG      S +    PI       +G +   S   S+  KTHG LMV+AWV C+S+GVILARYYKE+WP +G+  E VWFQ HR LQ +CV+LT +A IL F    GYS++   P+  HPILG+IVF LA LNPL+  CRC+ +  DRPWFNW HFFIG+ A+ LSVPT+M+G+R+   G QL +L  P WILIFFV+FQF +E+ILEIHGC+YY RNK+K+  Y  E+ +Y A +     P++KP  P+ SGRMFKY ++G+H
Sbjct:   25 VSVVGCGTIKGCL-FPPICTDSYCEFMATWKLVTHNAEDYVEFELRGKLNDPGGFLSLAFSEDKKISTAGVVGCYHHAATGTVRARAGY----NSGKTNTFYTGPDTELLISEGDN-LGGTYNPADKVLQCRFRRRVRPRDMVLQLKDLSEPNAYYLTITRGNDVLPSGFSRPFAGGEATYDSSVLITSPI-------YGSMTVISEQGSALMKTHGCLMVLAWVLCASIGVILARYYKELWPNSGLLGERVWFQSHRILQFSCVILTCIAIILAFIYCEGYSRVSTFPHYVHPILGLIVFCLALLNPLITFCRCKVDHPDRPWFNWIHFFIGTFAHVLSVPTMMLGLRMPAAGFQLQFLNYPLWILIFFVIFQFCIELILEIHGCMYYNRNKNKRREYMRELTQYHAGVRTALGPRSKPPEPEPSGRMFKYFIIGLH 449          
BLAST of Cytochrome b561/ferric reductase transmembrane,domain-containing protein vs. Ensembl Cavefish
Match: frrs1b (ferric chelate reductase 1 [Source:NCBI gene;Acc:103030884])

HSP 1 Score: 150.599 bits (379), Expect = 2.269e-38
Identity = 122/397 (30.73%), Postives = 180/397 (45.34%), Query Frame = 2
Query:  191 CESEKACFKSSKYCTYDSCDFAISWKPFSYMNNDYIEFEMVGTVFGDNSYMLVGFSDDTSLGNDGFVSCHVESKKVKVVAGFYEVGDTPESNIKFSNDVSLLVANSDKRYGGVYNEDTKRLTCRFLRQTRPQNANNQYKDLSLGNEYYLFTARGNEASQYGYGPPTAGSLIFSKHPIDFSRGSFHGVIGESSRVDSSFAKTHGILMVIAWVFCSSVGVILARYYKEMWPYTGIAKEMVWFQFHRSLQGTCVLLTTVAFILIFASVGGYSKLDRSPYVAHPILGIIVFILAFLNPLVALCRCRPNSKDRPWFNWFHFFIGSIAYCLSVPTIMIGMRISGPGRQLAYLESPQW---ILIFFVLFQFAVEIILEIHGCLYYRRNKDKKHTYEMEMEEYQA 1372
            C   K+C +    C  D  + A+ +       +D + FE+ G   G   Y+    S D  +G D    C  E  +V + A + +    P   +  S +V  L     +   GV       + CRF R  R    N    +L     +YLF A G   ++ G         + S +P+ F  GS   + G  S +     K H + M+IAW+   S GVI+ARY+K  WP T +  + VWFQFHR+L    VLLT + FIL F   GG+SK   S    HP LG  V  LA + P++AL R  P+S  R  FNW H   G+IA  ++V  + +G+       Q A L    W   I+  +V++    ++ILE+H    +   +  KH +E+  E  Q 
Sbjct:  207 CGITKSCLREPAAC--DPQNDALCYFLSFAKEDDSVVFELSGPAPG---YVSFALSTDKWMGEDDVYLCINEGSQVSINAAYVQGRTHP---VIASENV--LRDTEGRLVDGV-------IQCRFRRVVRIPAPNQNRSNLD--EAHYLFMAHGR--AENGRTHRHDRQPLISSNPV-FITGSPEDLTGSRSPL---LIKFHAVFMLIAWMTTVSTGVIIARYFKPNWPDTTLCGQRVWFQFHRALMLVTVLLTGIGFILPFIYRGGWSKRAGS----HPYLGCTVMALALIQPIMALFRPAPDSSRRYIFNWLHLGTGTIAQVIAVVAVCLGI------HQQALLLPAPWSTGIVAGYVIWFVLADLILEVHSRGLFPIGQFFKH-FEVHTENIQT 567          
BLAST of Cytochrome b561/ferric reductase transmembrane,domain-containing protein vs. Ensembl Cavefish
Match: wu:fj05g07 (putative ferric-chelate reductase 1 [Source:NCBI gene;Acc:103033089])

HSP 1 Score: 130.954 bits (328), Expect = 9.297e-33
Identity = 117/420 (27.86%), Postives = 175/420 (41.67%), Query Frame = 2
Query:  170 ESMSFQTCESEKACFKSSKYC---TYDSCDF-AISWKPFSYMNNDYIEFEMVGTVFGDNSYMLVGFSDDTSLGNDGFVSCHVESKKVKVVAGFYEVGDTPESNIKFSNDVSLLVANSDKRYGGVYNEDTKRLTCRFLRQTRPQNANNQYKDLSLGNEYYLFTARGNEASQYGYGPPTAGSLIFSKHPIDFSRGSFHGV--IGESSRVD------------SSFAKTHGILMVIAWVFCSSVGVILARYYKEMWPYTGIAKEMVWFQFHRSLQGTCVLLTTVAFILIFASVGGYSKLDRSPYVAHPILGIIVFILAFLNPLVALCRCRPNSKDRPWFNWFHFFIGSIAYCLSVPTIMIGMRISGPGRQLAYLES----PQWILIFFVLFQFAVEIILEIHGCLYYRRNKDKKHTYEMEMEE 1363
            +S+S   C +EK CF     C      SC F A++  P        I  E+ G   G   Y+  GFSDD  +GND    C  +S     V   +  G +  + +   N   +  + SD   G           C F+ +  P +A    +  S    Y+L          Y YG    G +             FHG       SRVD             S +K HG LM+IAW+  SSVG+I ARY K +    G + + VWF  H SL    V++T +AFIL FA + G++         HP+LG +V IL+ + P+ A  RC P  + R  FNW H  +  +   L+V  I  G+ +     +  +L+       W  +FF+L +            ++++R +DK+   E+   E
Sbjct:   19 KSISSAGCGTEKVCFSQPPDCDPAADPSCYFMAVTALP----TASGISVELQGRAEG---YISFGFSDDQRMGNDDIYICGTDSNGTVQVQHAFSTGRSRPTIVPLGNVSDITASMSDGVIG-----------CSFISR-NPISAGGMTEQNS---TYFLL---------YAYGSTIDGLI------------QFHGTNRFISDSRVDVLNPQIVKRAHHPSASKAHGSLMLIAWMTTSSVGMITARYLKAVGKGKGCSSKDVWFLAHVSLMSFTVIITAIAFILEFAHIKGWAG------GVHPVLGCLVMILSLIQPVAAAFRCSPQHEKRFVFNWMHGIMALVIKVLAVAAIFTGLALFDDSPEKWFLQVMGGFVGWEALFFILQE----------SNMWWKRKEDKESADELVSTE 379          
BLAST of Cytochrome b561/ferric reductase transmembrane,domain-containing protein vs. Ensembl Cavefish
Match: frrs1a (ferric-chelate reductase 1a [Source:ZFIN;Acc:ZDB-GENE-070705-45])

HSP 1 Score: 115.931 bits (289), Expect = 9.962e-27
Identity = 118/395 (29.87%), Postives = 165/395 (41.77%), Query Frame = 2
Query:  170 ESMSFQTCESEKACFKSSKYC--TYDSCDFAISWKPFSYMNNDYIEFEMVGTVFGDNSYMLVGFSDDTSLGNDGFVSCHVESKKVKVVAGFYEVGDTPESNIKFS-NDVSLLVANSDKRYGGVYNEDTKRLTCRFLRQTR-PQNANNQYKDLSLGNEYYLFTARGNEASQYGYGPPTAGSLIFSKHP----IDFSRGSFHGV--IGESSRVDSSFAKTHGILMVIAWVFCSSVGVILARYYKEMWPYTGIAKEMVWFQFHRSLQGTCVLLTTVAFILIFASVGGYSKLDRSPYVAHPILGIIVFILAFLNPLVALCRCRPNSKDRPWFNWFHFFIGSIAYCLSVPTIMIGMRISGPGRQLAYLESPQWILIFFVLFQFAVEIILEIHGCLYYRRN 1324
            +  S   C  EK+C     +C    D+  F +S++         ++FE+ G   G   Y+    S+D  +GND    C  +  +V V A +      PE   K   +DV   VA+      GV       + CRF R    P++        SL + YYLF A G  A++ G         +  KH     I   R +  G   I   SR      K HG LM+ AW+   S G+ +A ++K  WP   +  + +WF  H SL    V+ T V FIL F   G +S+       AH  LG  V  L  + P++A  R  P+S  R  FNW H  +G  A  L+  TI  GM      +Q   L  P W    FV   F + +IL       YRRN
Sbjct:  217 QPFSSDGCGQEKSCLLDPVHCNPATDTHCFFLSYR----TEGSSVQFELSGPAPG---YVSFALSEDKWMGNDDVYLCVNDGGRVSVEAAYATGRTHPEIADKAELSDVGWRVAD------GV-------IQCRFRRAISIPEDPQR----FSLNHSYYLFIAHG--AAEDG---------LIHKHKRQPLISAQRQAITGPPEIATGSR-SPLMMKYHGALMLFAWMVLGSTGIFMAGFFKPDWPEKTLFGQRIWFMVHHSLMMLTVIFTFVGFILPFIYRGHWSRGAS----AHAGLGCTVMSLTVIQPIMAFFRPSPDSSRRWIFNWMHRGVGKTAELLAGITISYGMH-----QQSLLLPFP-WTTGVFV--GFIILVILSKVILFVYRRN 563          
BLAST of Cytochrome b561/ferric reductase transmembrane,domain-containing protein vs. Ensembl Cavefish
Match: wu:fj05g07 (wu:fj05g07 [Source:ZFIN;Acc:ZDB-GENE-030131-7307])

HSP 1 Score: 99.3673 bits (246), Expect = 1.378e-21
Identity = 96/342 (28.07%), Postives = 140/342 (40.94%), Query Frame = 2
Query:  179 SFQTCESEKACFKSSKYC--TYDSCDFAISWKPFSYMNNDYIEFEMVGTVFGDNSYMLVGFSDDTSLGNDGFVSCHVESKKVKVVAGFYEVGDTPESNIKFSN--DVSLLVANSDKRYGGVYNEDTKRLTCRFLRQTRPQNANNQYKDLSLGNEYYLFTARGNEASQYGYGPPTAGSLIFSKHPIDFSRGSFHGVIGESSRVDSSFAKTHGILMVIAWVFCSSVGVILARYYKEMWPYTGIAKEMVWFQFHRSLQGTCVLLTTVAFILIFASVGGYSKLDRSPYVAHPILGIIVFILAFLNPLVALCRCRPNSKDRPWFNWFHFFIGSIAYCLSVPTIMIGM 1192
            S   C S K CF +   C  + DS  + +S  P    +     FE+VG   G   Y+ +GFSDDT +GND    C   S     +   +  G T  ++I   +  D+S+   N      GV       ++C F       N+ +  +  S G+ YY+F A         YGP                                     +G LM+IAW+   SVG+++ARY K+    T    +  WF  H  L    V  T +AFIL+F+    ++        AHP+LG++V IL+   P+ AL RC P  + R  FNW H         L+V  I  G+
Sbjct:  186 SLTGCGSTKTCFSNPSDCDPSTDSSCYFMSSTP----SGSQHRFEIVGPSSG---YVAIGFSDDTEMGNDDIYICGKNSSGSIQLQHAFSTGTTTPTSIDLGSVSDISVSTLN------GV-------ISCSF----TSANSISTTRSSSTGSSYYIFLA---------YGP-----------------------------------TQNGCLMLIAWMTTGSVGMLIARYLKKTAKGTRCCGKDFWFVAHVFLMILSVAATIIAFILVFSYAKDWAG------GAHPVLGVLVMILSLAQPIAALFRCGPQDERRYIFNWAHSINALAIKGLAVAAIFTGL 453          
BLAST of Cytochrome b561/ferric reductase transmembrane,domain-containing protein vs. Ensembl Cavefish
Match: frrs1l (ferric chelate reductase 1 like [Source:NCBI gene;Acc:103029610])

HSP 1 Score: 50.447 bits (119), Expect = 2.381e-6
Identity = 53/192 (27.60%), Postives = 88/192 (45.83%), Query Frame = 2
Query:  161 DALESMSFQTCESEKACFKSSKY-CTYDSCDFAISWKPFSYMNNDYIEFEMVGTVFGDNSYMLVGFSDDTSLGNDGFVSC-HVESKKVKVVAGFYEVGDTPESNIKFSNDVSLLVANSDKRYGGVYNEDTKRLTCRFLRQTRPQNANNQYK--DLSLGNEYYLFTARGNEASQYGYGPPTAGSLIFSKHPID 724
            D    +    C   K C +  K  C  ++CD+ +S   F  +  D +EFEM     G   ++ VGFS D  +G D  + C H ++ +V+ +  FY VG       +++ ++    A  ++   G++  +  R+TCRF    RP +   +    DL L + YYLF           +GP   GS+  ++H ID
Sbjct:   76 DPFARIKVSDCGITKGCIRYGKPGCDAETCDYFLS---FRRIGTD-VEFEMSADTDG---WVAVGFSSDKKMGGDDVMGCVHDDNGRVR-IHHFYNVG-------QWAKEIKRNPARDEE---GIF--ENNRVTCRF---KRPLHVPREETLVDLHL-SWYYLF----------AWGPAIQGSI--TRHDID 231          
BLAST of Cytochrome b561/ferric reductase transmembrane,domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005593.1 (pep scaffold:Pmarinus_7.0:GL493051:1963:3473:-1 gene:ENSPMAG00000005086.1 transcript:ENSPMAT00000005593.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 59.6918 bits (143), Expect = 1.303e-11
Identity = 22/42 (52.38%), Postives = 32/42 (76.19%), Query Frame = 2
Query:  788 KTHGILMVIAWVFCSSVGVILARYYKEMWPYTGIAKEMVWFQ 913
            K HG LM++AW+ C+SVG++LAR++K +WP   I  + VWFQ
Sbjct:   46 KAHGALMMVAWLTCASVGIVLARFFKPLWPTHYIWGQKVWFQ 87          
BLAST of Cytochrome b561/ferric reductase transmembrane,domain-containing protein vs. Ensembl Nematostella
Match: EDO34492 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SP75])

HSP 1 Score: 127.872 bits (320), Expect = 6.944e-31
Identity = 123/468 (26.28%), Postives = 190/468 (40.60%), Query Frame = 2
Query:  191 CESEKACFKSSKYCT-YDSCDFAISWKPFSYMNNDYIEFEMVGTVFGDNSYMLVGFSDDTSLGNDGF--VSCHVESKKVKVVAGFYEVGDTPESNIKFSNDVSLLVANSDKRYGGVYNEDTKRLTCRFLRQTRPQNANNQYKDLSLGNEYYLFTARGNEASQYGYGPPTAGSL-------IFSKHPIDFSRGSFHGVIGESSRVDSSFAKTHGILMVIAWVFCSSVGVILARYYKEMWPYTGIAKEMVWFQFHRSLQGTCVLLTTVAFILIFASVGGYSKL------------DR--------------------------SPYVAHPILGIIVFILAFLNPLVALCRCRPNSKDRPWFNWFHFFIGSIAYCLSVPTIMIGMRISGPGRQLAYLESPQWILIFFVLFQFAVEIILEIHGCLYYRRNKDKKHTYEMEMEEYQAALIANHAPQTKPISPKQSGRMFKYVM 1450
            C   K C+   + C  +  C + +++K     N   IEFE+       N ++ +GFS     G DG   + C   + KV++     +    PE     + D SL+         GV   D+ R  C+FLR+  P  AN +    +L  +++L    G          P +GS+       IFSK  ID        +I E+  + S+  K HG +M IAW+  ++V + +ARY K  W    I  +++WFQ HR+     VLL+ V  ILIF  V G+S +            DR                            + AHP +GI    LA + P +AL R  P ++ R  FNW H F+G  A  L+V T+ +        R L           F+VL  + + II  +   +  R +  K   + +E        +    PQ   +S    GR  + V+
Sbjct:  339 CGETKGCYAEPQGCKDHTDCKYLVTYKTNGAGN---IEFELTA----KNDWVAIGFSYKNK-GMDGIDTMVCATVAGKVELHHYALKGYSLPEKTTLNAGDTSLVF--------GVREGDSTR--CKFLRKISPGTANLR----ALDRKWHLVFGDG----------PVSGSVQKHTKTPIFSKSKIDLR---VSAIIRETEGI-SALVKAHGCVMSIAWLAFATVAIFMARYMKSAWKGEKIFGKLIWFQVHRAFMMVVVLLSCVGLILIFLHVEGWSDVCGAILCIVLCYCDRLGVKCELMYCVMLLRSLRCGALGRVQRSWGAHPYMGITAVGLAVIQPFMALLRPGPAAEKRFIFNWAHRFVGISALTLAVATLFLATLNYHFIRNLGLKNG------FWVLIAYCIGIIFVLIFEIMQRASPSKSKGFTLEKSTGMVEQMGMQQPQ---LSLTSDGRKHRLVL 761          
BLAST of Cytochrome b561/ferric reductase transmembrane,domain-containing protein vs. Ensembl Nematostella
Match: EDO34476 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SP71])

HSP 1 Score: 112.079 bits (279), Expect = 8.680e-26
Identity = 110/449 (24.50%), Postives = 185/449 (41.20%), Query Frame = 2
Query:  191 CESEKACFKSSKYC-TYDSCDFAISWKPFSYMNNDYIEFEMVGTVFGDNSYMLVGFSDDTSLGN-DGFVSCHVESKKVKVVAGFYEVGD--TPESNIK-----FSNDVSLLVAN--------SDKRYGGV---YNEDTKRLTCRFLRQTRPQNANNQYKDLSLGNEYYLFTARGNEASQYGYGPPTAGSLIFSKHPIDFSRGSFHGVIGESSRVDSSFAKTHGILMVIAWVFCSSVGVILARYYKEMWPYTGIAKEMVWFQFHRSLQGTCVLLTTVAFILIFASVGGYSKLDRSPYVAHPILGIIVFILAFLNPLVALCRCRPNSKDRPWFNWFHFFIGSIAYCLSVPTIMIG-------MRISGPGRQLAYLESPQWILIFFVLFQFAVEIILEIHGCLYYRRNKDKKHTYEMEMEEYQAALIANHAPQTKPISPKQSGRMFKYVMLG 1456
            C   KAC    K C T   C + +++     + ND + F M  T  G   +  +GF+    + + D  +     +    V    YE+     P  N +     +++   LL+A         S   Y GV     + +    CRF R+ +          + L  + YL  ARG  ++Q      +     ++  P+  +  +   V   +   D S  + H ILM IAW+ C+S+ + +ARY +E+W    I     WFQ HR L    ++ + V  +L F   GG+S+      +AHP++G+IV  LA + P++A  R +P +  R  FNW H  +G I+  L+V    +G       ++ SG    +AY      +++F        EI L          N + K     E  E           +TK + P +  +  K +++G
Sbjct:  357 CGKTKACVSEPKNCRTSSDCQYLMTYT----VENDDVIFHM-STSLG---WSAIGFNSKPRMDDTDALICSRTATSGDSVGVAHYEITGYGKPVKNTQVYHNTYNSHRLLLIAGVSQYLQRPSLAAYAGVSQYLQQPSLAAYCRFSRKKQSLGM------MDLNKKVYLIFARGQISAQGDLRQHSPREKSYTTDPVAITSLTDLKV---TEGKDLSLLRGHAILMSIAWLVCASLSMFVARYMREVWGE--IFGLKAWFQVHRGLMVLTLVFSVVGIVLAFVYAGGWSETK----IAHPLIGMIVLALACIQPVMAYFRPKPGTDKRVVFNWAHRSVGVISLALAVVNCFLGVLLPHFELQTSGTYPLIAYCAGVGLVILF--------EIYLACKARSQSSANLEAKADIRNEDVEV----------KTKQVKPVEQYKSLKKIVMG 764          
BLAST of Cytochrome b561/ferric reductase transmembrane,domain-containing protein vs. Ensembl Nematostella
Match: EDO43912 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RX71])

HSP 1 Score: 109.768 bits (273), Expect = 1.082e-25
Identity = 103/346 (29.77%), Postives = 154/346 (44.51%), Query Frame = 2
Query:  119 IKILVFIISLVFVCDALESMSFQTCESEKACFKSSKYCTYDS-CDFAISWKPFSYMNNDYIEFEMVGTVFGDNSYMLVGFSDDTS--LGNDGFVSCHVESKKVKVVAGFYEVGDTPESNIKFSNDVSLLVANSDKRYGGVYNEDTKRLTCRFLRQTRPQNANNQYKDLSLGNEYYLFTARGNEASQYGYGPPTAGSLIFSKHPIDFSRGSFHGVI---GESSRVDSSFAKTHGILMVIAWVFCSSVGVILARYYKEMWPYTGIAKEMVWFQFHRSLQGTCVLLTTVAFILIFASVGGYSKLDRSPYVAHPILGIIVFILAFLNPLVALCRCRPNSKDRPWFNWFHF 1138
            I +L+FI+ L  V   LE +S   C+  K C      C   S C++ +++        D + FEM       + ++ +GF+ D +  +G D  + C   +    ++ G Y +       I       L    S +  GG+       + C F R   P  ++N   DLS  N+ YL  ARG  AS            I   H    S  +   V+   G  SR   +   THG LM+IAWV  ++VG+  ARY +  W  + I   +VWFQ HRS     VL T ++ IL+F  VGG+S++      AH  +GI V +LA L P++A+ R  P      + NW  F
Sbjct:    7 IYLLIFILGL-GVSSGLE-ISKSGCKETKGCVSFPYDCKGSSDCNYLVTY----VAGKDSVYFEMSA----KDDWVSIGFNQDKAGMVGTDAII-CSRPASGSSILIGHYYLSSKNTPTITTPTPTGLF-NTSGEFNGGI-------IRCSFTRNKVP--SSNMKYDLS--NKQYLVYARGEVASG-----------ILQYHSWKSSSSNKVDVLATTGAESR-KRALLLTHGALMLIAWVGFATVGMATARYMRTFWGDSKIMSLLVWFQIHRSCMVIVVLSTIISTILVFVYVGGWSEIG-----AHAYIGIAVLVLAVLQPMIAVFRPHPGDDKSHFPNWIWF 312          
BLAST of Cytochrome b561/ferric reductase transmembrane,domain-containing protein vs. Ensembl Nematostella
Match: EDO28805 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T5F6])

HSP 1 Score: 79.337 bits (194), Expect = 2.404e-17
Identity = 42/103 (40.78%), Postives = 62/103 (60.19%), Query Frame = 2
Query:  806 MVIAWVFCSSVGVILARYYKEMWPYTGIAKEMVWFQFHRSLQGTCVLLTTVAFILIFASVGGYSKLDRSPYVAHPILGIIVFILAFLNPLVALCRCRPNSKDR 1114
            M+IAWV  ++VG+  ARY +  W  + I   +VWFQ HRS     VL T ++ IL+F  VGG+S++      AH  +GI V +LA L P++A+ R  P  ++R
Sbjct:    1 MLIAWVGFATVGMATARYMRTFWGDSKIMSLLVWFQIHRSCMVIVVLSTIISTILVFVYVGGWSEIG-----AHAYIGIAVLVLAVLQPMIAVFRPHPGDENR 98          
BLAST of Cytochrome b561/ferric reductase transmembrane,domain-containing protein vs. Ensembl Nematostella
Match: EDO40900 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S609])

HSP 1 Score: 61.2326 bits (147), Expect = 6.063e-10
Identity = 48/175 (27.43%), Postives = 78/175 (44.57%), Query Frame = 2
Query:  794 HGILMVIAWVFCSSVGVILARYYKEMWPYTGIAKEMVWFQFHRSLQGTCVLLTTVAFILIFASVGGYSKLDRSPYVAHPILGIIVFILAFLNPLVALCRCRPN-----SKDRPWFNWFHFFIGSIAYCLSVPTIMIGMRISGPGRQLAYLESPQWILIFFVLFQFAVE-IILEIH 1300
            HGILM I W      G  +ARY++   P+        WF+ HR LQ + ++     F     SV      D   + AH  LG+ + I+  L PL A+ R   +     ++ R  + W H  +G +A  L++  I +G+        LA +    W + + VL  F V  +++E+ 
Sbjct:  355 HGILMFIGWGVLLQGGAFIARYFRHKDPW--------WFKMHRGLQVSGLVFAIGGFACAVVSV----PFDHLMF-AHGGLGLAIMIMGILQPLNAIIRPHKHRDGSPTRKRIIWEWCHKLLGRLALVLALINICLGL-------FLAVVPQVAWTVWYAVLGVFLVAYVVMELR 509          
BLAST of Cytochrome b561/ferric reductase transmembrane,domain-containing protein vs. Planmine SMEST
Match: SMESG000021389.1 (SMESG000021389.1)

HSP 1 Score: 937.562 bits (2422), Expect = 0.000e+0
Identity = 448/449 (99.78%), Postives = 448/449 (99.78%), Query Frame = 2
Query:  116 MIKILVFIISLVFVCDALESMSFQTCESEKACFKSSKYCTYDSCDFAISWKPFSYMNNDYIEFEMVGTVFGDNSYMLVGFSDDTSLGNDGFVSCHVESKKVKVVAGFYEVGDTPESNIKFSNDVSLLVANSDKRYGGVYNEDTKRLTCRFLRQTRPQNANNQYKDLSLGNEYYLFTARGNEASQYGYGPPTAGSLIFSKHPIDFSRGSFHGVIGESSRVDSSFAKTHGILMVIAWVFCSSVGVILARYYKEMWPYTGIAKEMVWFQFHRSLQGTCVLLTTVAFILIFASVGGYSKLDRSPYVAHPILGIIVFILAFLNPLVALCRCRPNSKDRPWFNWFHFFIGSIAYCLSVPTIMIGMRISGPGRQLAYLESPQWILIFFVLFQFAVEIILEIHGCLYYRRNKDKKHTYEMEMEEYQAALIANHAPQTKPISPKQSGRMFKYVMLGMH 1462
            MIKILVFIISLVFVCDALESMSFQTCESEKACFKSSKYCTYDSCDFAISWKPFSYMNNDYIEFEMVGTVFGDNSYMLVGFSDDTSLGNDGFVSCHVESKKVKVVAGFYEVGDTPESNIKFSNDVSLLVANSDKRYGGVYNEDTKRLTCRFLRQTRPQNANNQYKDLSLGNEYYLFTARGNEASQYGYGPPTAGSLIFSKHPIDFSRGSFHGVIGESSRVDSSFAKTHGILMVIAWVFCSSVGVILARYYKEMWPYTGIAKEMVWFQFHRSLQGTCVLLTTVAFILIFASVGGYSKLDRSPYVAHPILGIIVFILAFLNPLVALCRCRPNSKDRPWFNWFHFFIGSIAYCLSVPTIMIGMRISGPGRQLAYLESPQWILIFFVLFQFAVEIILEIHGCLYYRRNKDKKHTYEMEMEEYQAALIANHAPQTKPI PKQSGRMFKYVMLGMH
Sbjct:    1 MIKILVFIISLVFVCDALESMSFQTCESEKACFKSSKYCTYDSCDFAISWKPFSYMNNDYIEFEMVGTVFGDNSYMLVGFSDDTSLGNDGFVSCHVESKKVKVVAGFYEVGDTPESNIKFSNDVSLLVANSDKRYGGVYNEDTKRLTCRFLRQTRPQNANNQYKDLSLGNEYYLFTARGNEASQYGYGPPTAGSLIFSKHPIDFSRGSFHGVIGESSRVDSSFAKTHGILMVIAWVFCSSVGVILARYYKEMWPYTGIAKEMVWFQFHRSLQGTCVLLTTVAFILIFASVGGYSKLDRSPYVAHPILGIIVFILAFLNPLVALCRCRPNSKDRPWFNWFHFFIGSIAYCLSVPTIMIGMRISGPGRQLAYLESPQWILIFFVLFQFAVEIILEIHGCLYYRRNKDKKHTYEMEMEEYQAALIANHAPQTKPIPPKQSGRMFKYVMLGMH 449          
BLAST of Cytochrome b561/ferric reductase transmembrane,domain-containing protein vs. Planmine SMEST
Match: SMESG000061404.1 (SMESG000061404.1)

HSP 1 Score: 403.675 bits (1036), Expect = 1.806e-135
Identity = 207/453 (45.70%), Postives = 284/453 (62.69%), Query Frame = 2
Query:  119 IKILVFIISLVFVCDALESMSFQTCESEKACFKSSKYCTYDSCDFAISWKPFSYMNNDYIEFEMVGTVFGDNSYMLVGFSDDTSLGNDGFVSCHVE--SKKVKVVAGFYEVGDTPESNIKFSN---DVSLLVANSDKRYGGVYNEDTKRLTCRFLRQTRPQNANNQYKDLSLGNEYYLFTARGNEASQYGYGPPTAGSLIFSKHPIDFSRGSFHGVIGESSRVDSSFAKTHGILMVIAWVFCSSVGVILARYYKEMWPYTGIAKEMVWFQFHRSLQGTCVLLTTVAFILIFASVGGYSKLDRSPYVAHPILGIIVFILAFLNPLVALCRCRPNSKDRPWFNWFHFFIGSIAYCLSVPTIMIGMRISGPGRQLAYLESPQWILIFFVLFQFAVEIILEIHGCLYYRRNKDKKHTYEMEMEEYQAALIANHAPQTKPISPKQSGRMFKYVMLGMH 1462
            +K+L  I SL+    A+  +SFQ C   KACFKS+K C+ D CD+ ++WK   Y    Y+E EM GTV     Y+ VGFS D  +G+DG V+C+    + ++ +VAG+ E+  +  SN   +N   D   LV  +   YGG +N D +RL+CRFLR   P+   +  KDLS G  YYL  A+G++  + G      GS + S+  IDF+ GSF+ VIG SS+++S  AK HGI+M+IAW+ C S+ V +ARYYK++W    I KE  WF  HR LQ    +L  +A I+I   VGGYSKL   P   HPI G IV IL  +NP +ALCRC+   K+RP FNW HF +G IAY LS+PTIMIG+++ G G +L++L  PQWI+  FV+ Q  +EIILEIHGC+ YR NKDK+H YE+E  EY+ A+  N+ P   P  P+  GR F+ ++LG +
Sbjct:    1 MKLLFLITSLLCYSSAVIQVSFQKCAVSKACFKSTKACSEDQCDYIVTWKSVKYNEKSYLEIEMTGTVLSTGGYIAVGFSVDKLMGDDGVVACYASPGTSEINIVAGYNEI--SKRSNKILTNKQLDKDFLVT-TGPNYGGNFNRDIRRLSCRFLRLVTPEKNADNLKDLSQGRRYYLLIAKGSDVGENGLNKHFPGSNVVSETSIDFTSGSFNSVIG-SSKINSPLAKAHGIIMIIAWMTCCSIAVFIARYYKDVWNRNPI-KEGSWFNPHRGLQSCGFVLIVIALIIIIVHVGGYSKLMEYPSKLHPIFGFIVIILFLINPFIALCRCQVRHKNRPIFNWIHFIVGIIAYILSIPTIMIGLKLPGAGLKLSHLNFPQWIIFIFVICQVILEIILEIHGCMTYRPNKDKRHNYELEKNEYEKAVQLNYKPDHIPKQPRIKGRNFRLLILGFY 448          
BLAST of Cytochrome b561/ferric reductase transmembrane,domain-containing protein vs. Planmine SMEST
Match: SMESG000042103.1 (SMESG000042103.1)

HSP 1 Score: 209.92 bits (533), Expect = 3.601e-61
Identity = 117/349 (33.52%), Postives = 177/349 (50.72%), Query Frame = 2
Query:  191 CESEKACFKSSKYCTYDSCDFAISWKPFSYMNNDYIEFEMVGTVFGDNSYMLVGFSDDTSLGNDGFVSCHVESKKVKVVAG------FYEVGDTPESNIKFSNDVSLLVANSDKRYGGVYNEDTKRLTCRFLRQTRPQNANNQYKDLSLGNEYYLFTARGNEASQYGYGPPTAGSLIFSKHPIDFSRGSFHGV---IGESSRVDSSFAKTHGILMVIAWVFCSSVGVILARYYKEMWPYTGIAKEMVWFQFHRSLQGTCVLLTTVAFILIFASVGGYSKLDRSPYVAHPILGIIVFILAFLNPLVALCRCRPNSKDRPWFNWFHFFIGSIAYCLSVPTIMIGMRISGPG 1210
            C   K+C   S  C + +C++A SWK  ++ +  Y+E E++G +   ++Y+ +GFS    + ++  V+C+ E+    ++AG      FY + D        S D +  V   D  YG  YN     L CRFLR  +P     + KDLS+  +YYL +A+               +L +      +S+ S++     +    R  +   K H  LM+  WVFCS+ G+I+A +YK  W  T    E VWFQ HR +Q  CV+  +  FI+IF  VGGYS L   PY AHP++GI+       NP++AL RC PN   R  FN  H  +G  AY L++ T +IG++  G G
Sbjct:   28 CGKSKSCLTWSS-CIWPNCEYAFSWKIKTFNSTKYLEIELIGRLTSSDAYLALGFSTVPKMKDNAVVACYKETDTTGILAGYNGDHKFYSLNDD-------SLDSNFFVKQMDDLYGAQYNATINVLQCRFLRLVQPTINVIKLKDLSV-TKYYLLSAKSAFLKH---------NLTYHSENKRYSQYSYNLTLDWVNSVIRNSNLLVKFHACLMIFGWVFCSTNGIIIANFYKNYWSKTSWFGEKVWFQLHRLIQTICVICVSSGFIIIFIYVGGYSALSSLPYSAHPVMGIVATGFMLSNPIMALFRCAPNHPSRKIFNRLHLLVGVTAYVLALATAIIGIQFLGDG 358          
BLAST of Cytochrome b561/ferric reductase transmembrane,domain-containing protein vs. Planmine SMEST
Match: SMESG000005729.1 (SMESG000005729.1)

HSP 1 Score: 66.2402 bits (160), Expect = 3.645e-11
Identity = 75/340 (22.06%), Postives = 138/340 (40.59%), Query Frame = 2
Query:  161 DALESMSFQTCESEKACFKSSKYCTYD--SCDFAISWKPFSYMNNDYIEFEMVGTVFGDNSYMLVGFSDDTSLGNDGFVSCHVESKKVKVVAGFYEVGDTPESNIKFSNDVSLLVANSDKRYGGVYN--EDTKRLTCRFLRQTRPQNANNQYKDL---SLGNEYYLFTARGNEASQYGYGPPTAGSLIFSKHPIDFSRGSFHGVIGESSRVD-------SSFAKTHGILMVIAWVFCSSVGVILARYYKEMWPYTGIAKEMVWFQFHRSLQGTCVLLTTVAFILIFASVGGYSKLDRSPYVAHPILGIIVFILAFLNPLVALCRCRPNSKDRPWFNWFHF 1138
            D  +S++   C + K C      C YD  +C + +S K    ++ + ++FE+VG    +  Y+ +  S+DT +G+D  + C   +          + G TP    K+   V+ +  N   +  G  N       L C+F     P+   +  K+L   +L    Y+F A GN      Y           KH  D    S   +I  S++           + K HG +M+++++    + +I+  +++  + Y    +++ WF  H  L     L++   +I I  +     ++       H I G +   L+ +N L+   R    S  R +F W HF
Sbjct:  187 DPNDSITIDGCGTTKNCLLYPLSC-YDRRNCKYMVSSK----VDGNNVDFELVGL---NKGYIAMALSNDTIMGDDLVIVC---ANNPNSPTPSLQTGYTPSGKRKYL--VTTVDPNIFNKKAGKMNFLNFENALVCKF---RIPRILVSPVKELIPKNLSESLYIFIANGNTYHSTAY---------VKKHS-DPPLISLTSIILYSTKNGIFYLQNLEYYKKVHGTIMILSFMILQPIAIIIVLHFRHNFSYRLKGRQL-WFNVHVLLNLLYFLMSLAGYIYILCN----KEILFQDAKFHGIFGTLAIGLSLINILMGFLRPDLTSDRRVYFKWIHF 495          
The following BLAST results are available for this feature:
BLAST of Cytochrome b561/ferric reductase transmembrane,domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 3
Match NameE-valueIdentityDescription
FRRS14.597e-3026.46ferric chelate reductase 1 [Source:HGNC Symbol;Acc... [more]
FRRS11.869e-2827.34ferric chelate reductase 1 [Source:HGNC Symbol;Acc... [more]
FRRS1L5.272e-828.13ferric chelate reductase 1 like [Source:HGNC Symbo... [more]
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BLAST of Cytochrome b561/ferric reductase transmembrane,domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
C05D12.11.036e-2325.36pep chromosome:WBcel235:II:11412232:11415820:-1 ge... [more]
C05D12.11.036e-2325.36pep chromosome:WBcel235:II:11412253:11415729:-1 ge... [more]
C05D12.11.036e-2325.36pep chromosome:WBcel235:II:11412253:11415772:-1 ge... [more]
C13B4.16.861e-2325.55pep chromosome:WBcel235:II:14470371:14479627:-1 ge... [more]
C13B4.19.185e-2126.24pep chromosome:WBcel235:II:14470523:14479627:-1 ge... [more]
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BLAST of Cytochrome b561/ferric reductase transmembrane,domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 2
Match NameE-valueIdentityDescription
CG83991.515e-3628.22gene:FBgn0034067 transcript:FBtr0087207[more]
CG83993.941e-3527.85gene:FBgn0034067 transcript:FBtr0340018[more]
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BLAST of Cytochrome b561/ferric reductase transmembrane,domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
frrs1a9.992e-3430.83ferric-chelate reductase 1a [Source:ZFIN;Acc:ZDB-G... [more]
frrs1b8.104e-3333.02ferric-chelate reductase 1b [Source:ZFIN;Acc:ZDB-G... [more]
frrs1a1.853e-2931.44ferric-chelate reductase 1a [Source:ZFIN;Acc:ZDB-G... [more]
wu:fj05g074.124e-2927.01wu:fj05g07 [Source:ZFIN;Acc:ZDB-GENE-030131-7307][more]
frrs1l9.241e-728.13ferric-chelate reductase 1-like [Source:ZFIN;Acc:Z... [more]
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BLAST of Cytochrome b561/ferric reductase transmembrane,domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
FRRS16.054e-3527.88ferric-chelate reductase 1 [Source:NCBI gene;Acc:1... [more]
FRRS11.105e-3428.11ferric-chelate reductase 1 [Source:NCBI gene;Acc:1... [more]
FRRS11.125e-3427.92ferric-chelate reductase 1 [Source:NCBI gene;Acc:1... [more]
FRRS12.554e-3427.97ferric-chelate reductase 1 [Source:NCBI gene;Acc:1... [more]
FRRS16.245e-3428.57ferric-chelate reductase 1 [Source:NCBI gene;Acc:1... [more]
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BLAST of Cytochrome b561/ferric reductase transmembrane,domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 4
Match NameE-valueIdentityDescription
Frrs12.030e-3327.63ferric-chelate reductase 1 [Source:MGI Symbol;Acc:... [more]
Frrs12.030e-3327.63ferric-chelate reductase 1 [Source:MGI Symbol;Acc:... [more]
Frrs16.679e-1444.19ferric-chelate reductase 1 [Source:MGI Symbol;Acc:... [more]
Frrs1l2.851e-826.61ferric-chelate reductase 1 like [Source:MGI Symbol... [more]
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BLAST of Cytochrome b561/ferric reductase transmembrane,domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q8MSU3|FRRS1_DROME1.518e-3528.22Putative ferric-chelate reductase 1 homolog OS=Dro... [more]
sp|Q6INU7|FRRS1_XENLA1.204e-3328.84Putative ferric-chelate reductase 1 OS=Xenopus lae... [more]
sp|Q8K385|FRRS1_MOUSE4.186e-3227.87Ferric-chelate reductase 1 OS=Mus musculus OX=1009... [more]
sp|Q6ZNA5|FRRS1_HUMAN2.208e-2926.46Ferric-chelate reductase 1 OS=Homo sapiens OX=9606... [more]
sp|A4QP81|FRRS1_DANRE2.328e-2327.30Putative ferric-chelate reductase 1 OS=Danio rerio... [more]
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BLAST of Cytochrome b561/ferric reductase transmembrane,domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A3Q0KUG73.692e-13047.60Ceramidase OS=Schistosoma mansoni OX=6183 PE=4 SV=... [more]
A0A0X3PKR91.258e-12743.90Ferric-chelate reductase 1 OS=Schistocephalus soli... [more]
A0A094ZJD14.493e-12245.59Ferric-chelate reductase 1 OS=Schistosoma haematob... [more]
A0A3R7FXV95.775e-12044.44Ferric-chelate reductase 1 OS=Clonorchis sinensis ... [more]
A0A074ZBH14.483e-11944.52Uncharacterized protein OS=Opisthorchis viverrini ... [more]
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BLAST of Cytochrome b561/ferric reductase transmembrane,domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
frrs1b2.269e-3830.73ferric chelate reductase 1 [Source:NCBI gene;Acc:1... [more]
wu:fj05g079.297e-3327.86putative ferric-chelate reductase 1 [Source:NCBI g... [more]
frrs1a9.962e-2729.87ferric-chelate reductase 1a [Source:ZFIN;Acc:ZDB-G... [more]
wu:fj05g071.378e-2128.07wu:fj05g07 [Source:ZFIN;Acc:ZDB-GENE-030131-7307][more]
frrs1l2.381e-627.60ferric chelate reductase 1 like [Source:NCBI gene;... [more]
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BLAST of Cytochrome b561/ferric reductase transmembrane,domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
ENSPMAT00000005593.11.303e-1152.38pep scaffold:Pmarinus_7.0:GL493051:1963:3473:-1 ge... [more]
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BLAST of Cytochrome b561/ferric reductase transmembrane,domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Cytochrome b561/ferric reductase transmembrane,domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO344926.944e-3126.28Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO344768.680e-2624.50Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO439121.082e-2529.77Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO288052.404e-1740.78Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO409006.063e-1027.43Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Cytochrome b561/ferric reductase transmembrane,domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Cytochrome b561/ferric reductase transmembrane,domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 4
Match NameE-valueIdentityDescription
SMESG000021389.10.000e+099.78SMESG000021389.1[more]
SMESG000061404.11.806e-13545.70SMESG000061404.1[more]
SMESG000042103.13.601e-6133.52SMESG000042103.1[more]
SMESG000005729.13.645e-1122.06SMESG000005729.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30019200 ID=SMED30019200|Name=Cytochrome b561/ferric reductase transmembrane,domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1812bp
AAATATATAGCGATATTTCAAATTGATTCTTGATTCAGACAATATTATTA
GTGATTATTTATTTTGGATTATCTCAATCTGATTGATATAGTATTTTGTA
ATATTGGATTACAACATGATTAAGATACTTGTCTTTATCATTTCATTGGT
TTTTGTTTGTGATGCGTTAGAATCGATGTCATTTCAAACTTGTGAATCAG
AAAAAGCATGCTTTAAGTCATCTAAATACTGTACTTATGACAGTTGTGAT
TTCGCCATATCATGGAAACCTTTTTCATATATGAATAATGATTACATTGA
ATTCGAAATGGTTGGCACTGTTTTTGGTGACAATAGCTATATGTTAGTTG
GATTCTCCGATGACACTTCATTGGGTAATGATGGATTTGTCAGTTGTCAT
GTGGAAAGTAAAAAAGTAAAAGTTGTTGCTGGATTTTACGAAGTTGGAGA
TACCCCAGAGTCTAATATAAAATTCAGTAACGATGTGAGCTTACTTGTGG
CGAATTCGGATAAGAGATACGGGGGAGTTTACAATGAGGATACGAAACGG
TTGACTTGTAGATTTCTGAGACAAACTAGACCGCAAAATGCAAATAACCA
ATATAAGGATTTATCTTTGGGAAATGAATATTACTTATTTACTGCCAGGG
GCAACGAAGCATCGCAATACGGCTATGGGCCACCCACTGCTGGAAGTTTG
ATTTTCAGTAAACATCCCATTGATTTCTCAAGAGGATCATTTCACGGTGT
GATTGGAGAATCTTCTAGAGTAGATTCATCCTTTGCAAAAACTCATGGAA
TTTTGATGGTGATTGCTTGGGTATTCTGTAGTTCTGTTGGAGTTATTCTT
GCCCGTTATTACAAAGAAATGTGGCCATATACAGGAATCGCTAAAGAAAT
GGTTTGGTTTCAATTTCATCGCAGTCTCCAAGGAACTTGTGTTTTACTCA
CTACAGTAGCTTTCATTCTTATATTCGCATCTGTCGGTGGTTATTCAAAA
TTGGATAGAAGCCCTTATGTAGCTCATCCTATTTTGGGAATAATAGTTTT
CATTTTGGCATTCCTTAATCCACTGGTAGCTCTATGTCGATGCCGACCAA
ACTCGAAAGATAGGCCATGGTTCAATTGGTTTCACTTCTTCATTGGATCT
ATCGCATATTGCCTGTCAGTTCCCACCATTATGATTGGAATGAGAATAAG
CGGACCTGGGCGTCAATTAGCTTATTTAGAGTCTCCACAATGGATTTTAA
TATTTTTTGTTTTGTTTCAATTTGCAGTTGAGATTATCCTAGAAATACAC
GGATGTTTGTACTACCGACGAAATAAAGATAAGAAGCACACATATGAAAT
GGAAATGGAAGAATATCAGGCAGCATTAATTGCTAATCATGCTCCCCAAA
CAAAACCGATTTCTCCAAAGCAATCTGGACGGATGTTCAAATATGTTATG
CTTGGAATGCATGCGATAGTTGCTGGAATCGTGACTCTCCTTCTCGTGAT
CATCATCGCAGTCAACTGAGCTCTAATTTCAAAAGAATGCTCCCCTCCTA
CTATTATATAATAATTCATTCTGCTCACTGAGTTTTGCATGGGATCTTAG
TCTGTTGATAGTTGCGTATGTCCTCAAAGAGTCTACTGATTTTCATTGCA
ATATTTATGCAATATATTCTTTTCGAGAGTTCTTTTATTGTGCATATTAT
TCATGTTCTCATCGAACATTTTGGTGCTTTATTTAGTATTTTTTGTTTAT
TTTGTGCAATTATCACAACTGTTATAATTAAAATAAATAAATCATTTACT
TTGAAAAAAAAA
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protein sequence of SMED30019200-orf-1

>SMED30019200-orf-1 ID=SMED30019200-orf-1|Name=SMED30019200-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=468bp
MIKILVFIISLVFVCDALESMSFQTCESEKACFKSSKYCTYDSCDFAISW
KPFSYMNNDYIEFEMVGTVFGDNSYMLVGFSDDTSLGNDGFVSCHVESKK
VKVVAGFYEVGDTPESNIKFSNDVSLLVANSDKRYGGVYNEDTKRLTCRF
LRQTRPQNANNQYKDLSLGNEYYLFTARGNEASQYGYGPPTAGSLIFSKH
PIDFSRGSFHGVIGESSRVDSSFAKTHGILMVIAWVFCSSVGVILARYYK
EMWPYTGIAKEMVWFQFHRSLQGTCVLLTTVAFILIFASVGGYSKLDRSP
YVAHPILGIIVFILAFLNPLVALCRCRPNSKDRPWFNWFHFFIGSIAYCL
SVPTIMIGMRISGPGRQLAYLESPQWILIFFVLFQFAVEIILEIHGCLYY
RRNKDKKHTYEMEMEEYQAALIANHAPQTKPISPKQSGRMFKYVMLGMHA
IVAGIVTLLLVIIIAVN*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000101muscle cell
PLANA:0000140anterior region of the whole animal
Vocabulary: INTERPRO
TermDefinition
IPR006593Cyt_b561/ferric_Rdtase_TM
IPR005018DOMON_domain
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
Vocabulary: biological process
TermDefinition
GO:0055114oxidation-reduction process
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 400..420
NoneNo IPR availableGENE3DG3DSA:1.20.120.1770coord: 204..399
e-value: 1.0E-6
score: 30.1
NoneNo IPR availablePANTHERPTHR45828FAMILY NOT NAMEDcoord: 19..412
NoneNo IPR availablePANTHERPTHR45828:SF3FERRIC-CHELATE REDUCTASE 1coord: 19..412
NoneNo IPR availableCDDcd08760Cyt_b561_FRRS1_likecoord: 191..394
e-value: 1.64286E-46
score: 157.506
NoneNo IPR availableSIGNALP_EUKSignalP-noTMSignalP-noTMcoord: 1..17
score: 0.894
NoneNo IPR availableTMHMMTMhelixcoord: 335..357
NoneNo IPR availableTMHMMTMhelixcoord: 227..249
NoneNo IPR availableTMHMMTMhelixcoord: 377..399
NoneNo IPR availableTMHMMTMhelixcoord: 301..323
NoneNo IPR availableTMHMMTMhelixcoord: 444..466
NoneNo IPR availableTMHMMTMhelixcoord: 269..291
IPR006593Cytochrome b561/ferric reductase transmembraneSMARTSM00665561_7coord: 226..359
e-value: 1.1E-25
score: 101.3
IPR006593Cytochrome b561/ferric reductase transmembranePFAMPF03188Cytochrom_B561coord: 227..359
e-value: 3.8E-10
score: 40.0
IPR006593Cytochrome b561/ferric reductase transmembranePROSITEPS50939CYTOCHROME_B561coord: 185..393
score: 21.969
IPR005018DOMON domainPFAMPF03351DOMONcoord: 43..179
e-value: 3.3E-9
score: 37.0
IPR005018DOMON domainPROSITEPS50836DOMONcoord: 44..179
score: 11.585