Neuronal acetylcholine receptor subunit alpha-6
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30019169 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 10
Homology
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Human
Match: CHRNA3 (cholinergic receptor nicotinic alpha 3 subunit [Source:HGNC Symbol;Acc:HGNC:1957]) HSP 1 Score: 135.961 bits (341), Expect = 1.418e-33 Identity = 76/298 (25.50%), Postives = 156/298 (52.35%), Query Frame = 1
Query: 121 EEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYVK-FNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAV 1008
E +L +L + ++ +RP A + VI++ ++ Q++ + + + W W DY+L W+P G + +P++K+W PD+ + N N DF +++ + + G VTW+ I SC +DV+YFPFD Q C + W +I +V + + + + EW I+ + + + Y I+ S+ ++R PL++ I +++P ++S L L+F L D G+++T+ +S++LS+T+++++++ P + +P++ YLL + +++S V+ V
Sbjct: 35 EHRLFERLFEDYNEIIRPVA--NVSDPVIIHFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYN---NAVGDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYW----ESGEWAIIKAPGYKHDIKYNCCEEIYPDITYSLYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITV 323
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Human
Match: CHRNA6 (cholinergic receptor nicotinic alpha 6 subunit [Source:HGNC Symbol;Acc:HGNC:15963]) HSP 1 Score: 135.961 bits (341), Expect = 1.776e-33 Identity = 80/299 (26.76%), Postives = 156/299 (52.17%), Query Frame = 1
Query: 121 EEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVD-NSYLPNSNISEW-IILYVKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAV 1008
EE+L +L ++ +RP + V V+ + Q+ + + + W W DY+L W P I + +P++K+W PD+ + N N DF + +++ + ++G +TW I SCP+D+++FPFD Q C + W +I ++ + GS VD N + N SEW II + + + Y I+ S ++R P+++ I +++P +S L L+F L D G+++T+ +S++LS+T+++++++ P + +P++ YLL + +++S V+ V
Sbjct: 34 EERLFHKLFSHYNQFIRPVE--NVSDPVTVHFEVAITQLANVDEVNQIMETNLWLRHIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYN---NAVGDFQVEGKTKALLKYNGMITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLII--GSKVDMNDFWEN---SEWEIIDASGYKHDIKYNCCEEIYTDITYSFYIRRLPMFYTINLIIPCLFISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVVPLVGEYLLFTMIFVTLSIVVTV 322
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Human
Match: CHRND (cholinergic receptor nicotinic delta subunit [Source:HGNC Symbol;Acc:HGNC:1965]) HSP 1 Score: 135.961 bits (341), Expect = 2.475e-33 Identity = 88/316 (27.85%), Postives = 164/316 (51.90%), Query Frame = 1
Query: 109 SFGDEEKLITQLM--KRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNI----------SEWIILY--VKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTLD-DSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAVV 1011
+EE+LI L K ++ ++RP A +V V + + +++ + EET + + W W D RL W+ + GNI+ + LP + +WLP++ + NN D F + V H G V W+ I SCP+ V+YFPFD Q C + + + K+I + Q +N P I EW I++ + N + + Q I+ + ++R+PL++II +LVP ++S + L+F L DSG++ +VA+S++L+ +++++++S P + +P++ +LL + L+++ V+ V+
Sbjct: 21 GLNEEERLIRHLFQEKGYNKELRPVA--HKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGNISVLRLPPDMVWLPEIVL---ENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTYFPFDWQNCSLKFSSLKYTAKEITLSLKQDAK--ENRTYPVEWIIIDPEGFTENGEWEIVHRPARVNVDPRAPLDSPSRQDITFYLIIRRKPLFYIINILVPCVLISFMVNLVFYLPADSGEKTSVAISVLLAQSVFLLLISKRLPATSMAIPLIGKFLLFGMVLVTMVVVICVI 329
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Human
Match: CHRNA3 (cholinergic receptor nicotinic alpha 3 subunit [Source:HGNC Symbol;Acc:HGNC:1957]) HSP 1 Score: 135.191 bits (339), Expect = 3.900e-33 Identity = 76/298 (25.50%), Postives = 156/298 (52.35%), Query Frame = 1
Query: 121 EEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYVK-FNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAV 1008
E +L +L + ++ +RP A + VI++ ++ Q++ + + + W W DY+L W+P G + +P++K+W PD+ + N N DF +++ + + G VTW+ I SC +DV+YFPFD Q C + W +I +V + + + + EW I+ + + + Y I+ S+ ++R PL++ I +++P ++S L L+F L D G+++T+ +S++LS+T+++++++ P + +P++ YLL + +++S V+ V
Sbjct: 35 EHRLFERLFEDYNEIIRPVA--NVSDPVIIHFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYN---NAVGDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYW----ESGEWAIIKAPGYKHDIKYNCCEEIYPDITYSLYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITV 323
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Human
Match: CHRNA3 (cholinergic receptor nicotinic alpha 3 subunit [Source:HGNC Symbol;Acc:HGNC:1957]) HSP 1 Score: 135.191 bits (339), Expect = 3.900e-33 Identity = 76/298 (25.50%), Postives = 156/298 (52.35%), Query Frame = 1
Query: 121 EEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYVK-FNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAV 1008
E +L +L + ++ +RP A + VI++ ++ Q++ + + + W W DY+L W+P G + +P++K+W PD+ + N N DF +++ + + G VTW+ I SC +DV+YFPFD Q C + W +I +V + + + + EW I+ + + + Y I+ S+ ++R PL++ I +++P ++S L L+F L D G+++T+ +S++LS+T+++++++ P + +P++ YLL + +++S V+ V
Sbjct: 35 EHRLFERLFEDYNEIIRPVA--NVSDPVIIHFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYN---NAVGDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYW----ESGEWAIIKAPGYKHDIKYNCCEEIYPDITYSLYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITV 323
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Celegans
Match: acr-21 (pep chromosome:WBcel235:III:6581927:6586549:1 gene:WBGene00000060.1 transcript:F27B3.2b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:acr-21) HSP 1 Score: 135.961 bits (341), Expect = 1.851e-33 Identity = 82/323 (25.39%), Postives = 173/323 (53.56%), Query Frame = 1
Query: 58 LSIFINSSRGAGFHDYSSFGDEE--KLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSR-MSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQI-LMVPVQHGSTVDNSYLPNSNISEWIILYVKFNYKTYV-SQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAV 1008
+S+F+ + G ++ SS D+ +L L+ ++ +VRP+ + V +++ QI+ + + + + W L W DY+L W P+ N+T++ +PS+K+W PD+ + NN D + S + V + G++ W I SCPLDV ++PFD QTC + W +I L++ + G + Y+ N +EW ++ ++ + S Y +I + + ++R+ ++++ +++P ++S +A + F + DSG+++T+ ++ +LS T+++++V+ P + LP++ IY + L+++ T + V
Sbjct: 8 ISLFLFFNGAHGGNELSSRADQNVMRLYRDLLYDYNNEVRPSV--HSKEPINVTFVFSLTQIIDVDERNQILTTNSWIRLHWVDYKLVWDPRLYQNVTRIHIPSDKIWKPDIILY---NNADAQYMKSVMSTDVIVDYLGNIHWPLSAIFTSSCPLDVKHYPFDRQTCILKYASWAYDGTKIDLLLKSEQGDLTN--YITN---TEWSLIGIRAEKNQVIYSCCPEPYPFIDVHVTIERRAMFYVFNLILPCVLISLIALMGFYMPTDSGEKVTLGITSLLSTTVFLMMVAEGMPPTAEALPLIGIYFGVTIMLVALGTAMTV 320
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Celegans
Match: acr-21 (pep chromosome:WBcel235:III:6581927:6586549:1 gene:WBGene00000060.1 transcript:F27B3.2a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:acr-21) HSP 1 Score: 135.576 bits (340), Expect = 2.930e-33 Identity = 82/323 (25.39%), Postives = 173/323 (53.56%), Query Frame = 1
Query: 58 LSIFINSSRGAGFHDYSSFGDEE--KLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSR-MSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQI-LMVPVQHGSTVDNSYLPNSNISEWIILYVKFNYKTYV-SQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAV 1008
+S+F+ + G ++ SS D+ +L L+ ++ +VRP+ + V +++ QI+ + + + + W L W DY+L W P+ N+T++ +PS+K+W PD+ + NN D + S + V + G++ W I SCPLDV ++PFD QTC + W +I L++ + G + Y+ N +EW ++ ++ + S Y +I + + ++R+ ++++ +++P ++S +A + F + DSG+++T+ ++ +LS T+++++V+ P + LP++ IY + L+++ T + V
Sbjct: 8 ISLFLFFNGAHGGNELSSRADQNVMRLYRDLLYDYNNEVRPSV--HSKEPINVTFVFSLTQIIDVDERNQILTTNSWIRLHWVDYKLVWDPRLYQNVTRIHIPSDKIWKPDIILY---NNADAQYMKSVMSTDVIVDYLGNIHWPLSAIFTSSCPLDVKHYPFDRQTCILKYASWAYDGTKIDLLLKSEQGDLTN--YITN---TEWSLIGIRAEKNQVIYSCCPEPYPFIDVHVTIERRAMFYVFNLILPCVLISLIALMGFYMPTDSGEKVTLGITSLLSTTVFLMMVAEGMPPTAEALPLIGIYFGVTIMLVALGTAMTV 320
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Celegans
Match: acr-15 (AcetylCholine Receptor [Source:UniProtKB/TrEMBL;Acc:O16926]) HSP 1 Score: 130.183 bits (326), Expect = 4.168e-32 Identity = 98/383 (25.59%), Postives = 182/383 (47.52%), Query Frame = 1
Query: 121 EEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYVKFNYKTYVSQINIT----------YQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTLD-DSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYL--LNQLGLLSVSTVLAVVNQKLREKY---RLSFWQDYQQARTIFNGYYLEESPL-----MTDYCSDSPLATLKRAWQSQRYKNTKTETIFN 1206
E +LI LM + + RPT + V+V++ + QI+ S+ EE ++ W W+D L W P N+T + P + LW PD+ + N+ D +F + + + H G++ WM I VSC LD+ +FPFD Q CY W +I + + G + ++PN EWII+ +Y+T NIT Y+ I+ ++ ++R+ LY+ ++ P + L L FT+ ++ +++ + +S+ L++ +++ I+S P++ +P+L ++ N + +L+ S + V + R ++ R+ FW + LE SP M D ++ TL +W+ + + + T F
Sbjct: 22 EVRLINDLMSGYVREERPT--LDSSKPVVVSLGVFLQQIINLSEKEEQLEVNAWLKFQWRDENLRWEPTAYENVTDLRHPPDALWTPDILLY---NSVDSEFDSSYKVNLVNYHTGNINWMPPGIFKVSCKLDIYWFPFDEQVCYFKFGSWTYTRDKIQL---EKGDFDFSEFIPN---GEWIII----DYRT-----NITVKQYECCPEQYEDITFTLHLRRRTLYYSFNLIAPVLLTMILVILGFTVSPETCEKVGLQISVSLAICIFLTIMSELTPQTSEAVPLLGVFFHTCNFISVLATSFTVYVQSFHFRNQHVHERMDFWMRF---------ILLEWSPWLLRMKMPD--RENNFQTLTESWKGRNRRESMARTAFE 373
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Celegans
Match: acr-21 (pep chromosome:WBcel235:III:6583461:6586549:1 gene:WBGene00000060.1 transcript:F27B3.2d.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:acr-21) HSP 1 Score: 131.339 bits (329), Expect = 4.914e-32 Identity = 76/298 (25.50%), Postives = 160/298 (53.69%), Query Frame = 1
Query: 127 KLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSR-MSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQI-LMVPVQHGSTVDNSYLPNSNISEWIILYVKFNYKTYV-SQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAV 1008
+L L+ ++ +VRP+ + V +++ QI+ + + + + W L W DY+L W P+ N+T++ +PS+K+W PD+ + NN D + S + V + G++ W I SCPLDV ++PFD QTC + W +I L++ + G + Y+ N +EW ++ ++ + S Y +I + + ++R+ ++++ +++P ++S +A + F + DSG+++T+ ++ +LS T+++++V+ P + LP++ IY + L+++ T + V
Sbjct: 2 RLYRDLLYDYNNEVRPSV--HSKEPINVTFVFSLTQIIDVDERNQILTTNSWIRLHWVDYKLVWDPRLYQNVTRIHIPSDKIWKPDIILY---NNADAQYMKSVMSTDVIVDYLGNIHWPLSAIFTSSCPLDVKHYPFDRQTCILKYASWAYDGTKIDLLLKSEQGDLTN--YITN---TEWSLIGIRAEKNQVIYSCCPEPYPFIDVHVTIERRAMFYVFNLILPCVLISLIALMGFYMPTDSGEKVTLGITSLLSTTVFLMMVAEGMPPTAEALPLIGIYFGVTIMLVALGTAMTV 289
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Celegans
Match: unc-29 (Acetylcholine receptor subunit beta-type unc-29 [Source:UniProtKB/Swiss-Prot;Acc:P48181]) HSP 1 Score: 130.183 bits (326), Expect = 5.218e-32 Identity = 73/284 (25.70%), Postives = 153/284 (53.87%), Query Frame = 1
Query: 118 DEEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYVKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLL 966
DEE+L+ + + ++ ++P +IV + ++ ++ + ++ + W TL W D+++ W+P G I Q+ + +K+WLPD+ + NN D ++ + ++H G + W+ I SC +DV +FPFD Q C ++ W + +I + VQ VD S S+I W ++ V + S+I +R++R+ L++ +++++P +++ L+ +F L DSG+++T+ +S++LS+ +++++VS P + +P++ YLL
Sbjct: 29 DEERLMVDVFRGYNSLIQPVRN-SSELPLIVKMALQLVLLINVDEKDQVMHTNVWLTLQWHDFQMKWNPVNYGEIKQIRVSPDKVWLPDIVLF---NNADGNYEVSFMCNVVINHKGDMLWVPPAIYKSSCIIDVEFFPFDEQVCTLVFGSWTYNENEIKLEFVQ-AELVDVSEYSASSI--WDVIDVPASLVNKRSRIE-------FQVRIRRKTLFYTVVLIIPTVLMAFLSMAVFFLPTDSGEKITLTISVLLSIVVFLLLVSKILPPTSSTIPLMAKYLL 298
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Fly
Match: nAChRalpha2 (gene:FBgn0000039 transcript:FBtr0084639) HSP 1 Score: 147.902 bits (372), Expect = 1.779e-37 Identity = 86/309 (27.83%), Postives = 161/309 (52.10%), Query Frame = 1
Query: 118 DEEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDN---------SYLPNSNISEWIILYVKFN-YKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTLD-DSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAVV 1011
D ++L L+ ++ +RP + T V+V + + Q++ + ++ + + W WQD++ W P G +T++++PSE +WLPD+ + NN D ++ + ++ + + G V W I SC +DV YFPFD QTC++ W QI + + + DN Y P+ EW IL V ++ Y Y I +I ++R+ L++ + +++P +S L+ L+F L DSG+++ + +S++LS TM+ +++S P + LP+L YLL + L+ +S V+ ++
Sbjct: 44 DAKRLYDDLLSNYNRLIRPVS--NNTDTVLVKLGLRLSQLIDLNLKDQILTTNVWLEHEWQDHKFKWDPSEYGGVTELYVPSEHIWLPDIVLY---NNADGEYVVTTMTKAILHYTGKVVWTPPAIFKSSCEIDVRYFPFDQQTCFMKFGSWTYDGDQIDLKHISQKNDKDNKVEIGIDLREYYPS---VEWDILGVPAERHEKYYPCCAEPYPDIFFNITLRRKTLFYTVNLIIPCVGISYLSVLVFYLPADSGEKIALCISILLSQTMFFLLISEIIPSTSLALPLLGKYLLFTMLLVGLSVVITII 344
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Fly
Match: nAChRalpha2 (gene:FBgn0000039 transcript:FBtr0084640) HSP 1 Score: 147.902 bits (372), Expect = 1.779e-37 Identity = 86/309 (27.83%), Postives = 161/309 (52.10%), Query Frame = 1
Query: 118 DEEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDN---------SYLPNSNISEWIILYVKFN-YKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTLD-DSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAVV 1011
D ++L L+ ++ +RP + T V+V + + Q++ + ++ + + W WQD++ W P G +T++++PSE +WLPD+ + NN D ++ + ++ + + G V W I SC +DV YFPFD QTC++ W QI + + + DN Y P+ EW IL V ++ Y Y I +I ++R+ L++ + +++P +S L+ L+F L DSG+++ + +S++LS TM+ +++S P + LP+L YLL + L+ +S V+ ++
Sbjct: 44 DAKRLYDDLLSNYNRLIRPVS--NNTDTVLVKLGLRLSQLIDLNLKDQILTTNVWLEHEWQDHKFKWDPSEYGGVTELYVPSEHIWLPDIVLY---NNADGEYVVTTMTKAILHYTGKVVWTPPAIFKSSCEIDVRYFPFDQQTCFMKFGSWTYDGDQIDLKHISQKNDKDNKVEIGIDLREYYPS---VEWDILGVPAERHEKYYPCCAEPYPDIFFNITLRRKTLFYTVNLIIPCVGISYLSVLVFYLPADSGEKIALCISILLSQTMFFLLISEIIPSTSLALPLLGKYLLFTMLLVGLSVVITII 344
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Fly
Match: nAChRalpha1 (gene:FBgn0000036 transcript:FBtr0330310) HSP 1 Score: 129.028 bits (323), Expect = 4.697e-31 Identity = 84/322 (26.09%), Postives = 166/322 (51.55%), Query Frame = 1
Query: 118 DEEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSY----LPNSNIS-EWIILYV-KFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTV--LAVVNQKLRE--KYRLSFW 1050
D ++L L+ ++ +RP + + V + + Q++ + + + + W W DY+L W+P G + + +PSE +WLPD+ + N N D ++ ++ + H G V W I C +DV YFPFD QTC++ W + + ++ + DN L + IS EW I+ V + + S Y I ++ ++R+ L++ + +++P +S L+ L+F L DSG+++++ +S++LS+T++ ++++ P + +P+L YLL + L+++S V +AV+N R +R++ W
Sbjct: 24 DAKRLYDDLLSNYNRLIRPVG--NNSDRLTVKMGLRLSQLIDVNLKNQIMTTNVWVEQEWNDYKLKWNPDDYGGVDTLHVPSEHIWLPDIVLYN---NADGNYEVTIMTKAILHHTGKVVWKPPAIYKSFCEIDVEYFPFDEQTCFMKFGSWTYDGYMVDLRHLKQTADSDNIEVGIDLQDYYISVEWDIMRVPAVRNEKFYSCCEEPYLDIVFNLTLRRKTLFYTVNLIIPCVGISFLSVLVFYLPSDSGEKISLCISILLSLTVFFLLLAEIIPPTSLTVPLLGKYLLFTMMLVTLSVVVTIAVLNVNFRSPVTHRMAPW 340
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Fly
Match: nAChRalpha1 (gene:FBgn0000036 transcript:FBtr0334916) HSP 1 Score: 128.642 bits (322), Expect = 5.314e-31 Identity = 84/322 (26.09%), Postives = 166/322 (51.55%), Query Frame = 1
Query: 118 DEEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSY----LPNSNIS-EWIILYV-KFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTV--LAVVNQKLRE--KYRLSFW 1050
D ++L L+ ++ +RP + + V + + Q++ + + + + W W DY+L W+P G + + +PSE +WLPD+ + NN D ++ ++ + H G V W I C +DV YFPFD QTC++ W + + ++ + DN L + IS EW I+ V + + S Y I ++ ++R+ L++ + +++P +S L+ L+F L DSG+++++ +S++LS+T++ ++++ P + +P+L YLL + L+++S V +AV+N R +R++ W
Sbjct: 24 DAKRLYDDLLSNYNRLIRPVG--NNSDRLTVKMGLRLSQLIDVNLKNQIMTTNVWVEQEWNDYKLKWNPDDYGGVDTLHVPSEHIWLPDIVL---YNNADGNYEVTIMTKAILHHTGKVVWKPPAIYKSFCEIDVEYFPFDEQTCFMKFGSWTYDGYMVDLRHLKQTADSDNIEVGIDLQDYYISVEWDIMRVPAVRNEKFYSCCEEPYLDIVFNLTLRRKTLFYTVNLIIPCVGISFLSVLVFYLPSDSGEKISLCISILLSLTVFFLLLAEIIPPTSLTVPLLGKYLLFTMMLVTLSVVVTIAVLNVNFRSPVTHRMAPW 340
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Fly
Match: nAChRalpha1 (gene:FBgn0000036 transcript:FBtr0084619) HSP 1 Score: 128.642 bits (322), Expect = 5.314e-31 Identity = 84/322 (26.09%), Postives = 166/322 (51.55%), Query Frame = 1
Query: 118 DEEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSY----LPNSNIS-EWIILYV-KFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTV--LAVVNQKLRE--KYRLSFW 1050
D ++L L+ ++ +RP + + V + + Q++ + + + + W W DY+L W+P G + + +PSE +WLPD+ + NN D ++ ++ + H G V W I C +DV YFPFD QTC++ W + + ++ + DN L + IS EW I+ V + + S Y I ++ ++R+ L++ + +++P +S L+ L+F L DSG+++++ +S++LS+T++ ++++ P + +P+L YLL + L+++S V +AV+N R +R++ W
Sbjct: 24 DAKRLYDDLLSNYNRLIRPVG--NNSDRLTVKMGLRLSQLIDVNLKNQIMTTNVWVEQEWNDYKLKWNPDDYGGVDTLHVPSEHIWLPDIVL---YNNADGNYEVTIMTKAILHHTGKVVWKPPAIYKSFCEIDVEYFPFDEQTCFMKFGSWTYDGYMVDLRHLKQTADSDNIEVGIDLQDYYISVEWDIMRVPAVRNEKFYSCCEEPYLDIVFNLTLRRKTLFYTVNLIIPCVGISFLSVLVFYLPSDSGEKISLCISILLSLTVFFLLLAEIIPPTSLTVPLLGKYLLFTMMLVTLSVVVTIAVLNVNFRSPVTHRMAPW 340
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Zebrafish
Match: chrne (cholinergic receptor, nicotinic, epsilon [Source:ZFIN;Acc:ZDB-GENE-040808-32]) HSP 1 Score: 137.502 bits (345), Expect = 4.046e-34 Identity = 86/320 (26.88%), Postives = 170/320 (53.12%), Query Frame = 1
Query: 115 GDEE-KLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIIL--TPWQSHVKQILMVPVQHGSTVD------NSYLPNSNISEWIILY---VKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL--DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGL--LSVSTVLAVVNQKLR 1026
G+EE +LI K +S +RP V V + + +++ ++ EET + + W + W DYRL W+ +I Q+ +P +WLPD+ + NN D F + + +S DG + W+ I +C ++++YFPFD Q C ++ + ++ I++ ++G ++ ++ N EW I + K + Y S ++ YQ + +I +QR+PL+++I +++P S++S L L + L G +LTV++S++L+ T++++++S P + ++P++ YL+ + + L V+ + V+N LR
Sbjct: 26 GNEESQLIADKFKNYSKNIRPAR--HADEKVKVQVKLTLTNLISLNEKEETLTTNVWIEIQWHDYRLAWNTSEYHDIEQIRVPYYTVWLPDIVL---ENNIDGKFDVAYYANVLISSDGSMYWLPPAIYRSTCAIEITYFPFDWQNCTLVFRSQTYSANEIDIVLAEDENGKPIEWVDIDPEAFTEN---GEWAIKHRPARKLTNQRY-SPDDLEYQEVYYNIIIQRKPLFYVINIILPCSLISSLVVLAYFLPAKAGGQKLTVSISVLLAQTVFLILISQKIPETSLSVPLIGKYLIFVMSMTTLIVTNCIIVLNYSLR 336
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Zebrafish
Match: chrne (cholinergic receptor, nicotinic, epsilon [Source:ZFIN;Acc:ZDB-GENE-040808-32]) HSP 1 Score: 137.502 bits (345), Expect = 4.046e-34 Identity = 86/320 (26.88%), Postives = 170/320 (53.12%), Query Frame = 1
Query: 115 GDEE-KLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIIL--TPWQSHVKQILMVPVQHGSTVD------NSYLPNSNISEWIILY---VKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL--DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGL--LSVSTVLAVVNQKLR 1026
G+EE +LI K +S +RP V V + + +++ ++ EET + + W + W DYRL W+ +I Q+ +P +WLPD+ + NN D F + + +S DG + W+ I +C ++++YFPFD Q C ++ + ++ I++ ++G ++ ++ N EW I + K + Y S ++ YQ + +I +QR+PL+++I +++P S++S L L + L G +LTV++S++L+ T++++++S P + ++P++ YL+ + + L V+ + V+N LR
Sbjct: 26 GNEESQLIADKFKNYSKNIRPAR--HADEKVKVQVKLTLTNLISLNEKEETLTTNVWIEIQWHDYRLAWNTSEYHDIEQIRVPYYTVWLPDIVL---ENNIDGKFDVAYYANVLISSDGSMYWLPPAIYRSTCAIEITYFPFDWQNCTLVFRSQTYSANEIDIVLAEDENGKPIEWVDIDPEAFTEN---GEWAIKHRPARKLTNQRY-SPDDLEYQEVYYNIIIQRKPLFYVINIILPCSLISSLVVLAYFLPAKAGGQKLTVSISVLLAQTVFLILISQKIPETSLSVPLIGKYLIFVMSMTTLIVTNCIIVLNYSLR 336
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Zebrafish
Match: chrnb1l (cholinergic receptor, nicotinic, beta 1 (muscle) like [Source:ZFIN;Acc:ZDB-GENE-060811-1]) HSP 1 Score: 136.346 bits (342), Expect = 6.107e-34 Identity = 90/333 (27.03%), Postives = 176/333 (52.85%), Query Frame = 1
Query: 70 INSSRGAGFHDYSSFGDEEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNI--------SEWIILYVKFNYKTYVSQINI---TYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAVVNQKLREK 1032
IN SR A E +L+ L + ++LKVRP + V+V + ++Q+++ +Q + + + + W DYRL+W+P+ I V +P K+W PD+ ++ NN D F + V DG V+W+ I SC ++V+YFPFD Q C ++ ++S+ V +Q+G D + L I EW I + S+ NI Y+ I+ + ++R+PL+++I ++VP + S LA +F L +G+++T+++S+++++T+++++++ P + +P++ Y++ + L++ S +L+VV L +
Sbjct: 10 INGSRKAS-------EAERRLLEDLFQDYNLKVRPARTWN--ERVMVRVGMTLVQLISLNQKNGEMTTNVFMNMEWTDYRLSWNPEDYDKIDVVRIPPVKVWRPDIYLI---NNNDGQFDVALYVNVLVRSDGTVSWLPPAIYRSSCSIEVAYFPFDWQNCSMV---FRSYTYDSSEVDLQYGLDEDGNELHEIVIDENAFTENGEWQICHKP-------SRKNIQDDLYEDITFYLIIERKPLFYVINIIVPCILTSVLAIFVFYLPPGAGEKMTLSISVLIALTVFMLLLADKVPETSLAIPIIVNYVMFTMILVTFSVILSVVVLNLHHR 320
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Zebrafish
Match: chrnb1l (cholinergic receptor, nicotinic, beta 1 (muscle) like [Source:ZFIN;Acc:ZDB-GENE-060811-1]) HSP 1 Score: 135.961 bits (341), Expect = 8.043e-34 Identity = 89/330 (26.97%), Postives = 176/330 (53.33%), Query Frame = 1
Query: 70 INSSRGAGFHDYSSFGDEEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNI--------SEWIILYVKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAVVNQKLREK 1032
IN SR A E +L+ L + ++LKVRP + V+V + ++Q+++ +Q + + + + W DYRL+W+P+ I V +P K+W PD+ ++ NN D F + V DG V+W+ I SC ++V+YFPFD Q C ++ ++S+ V +Q+G D + L I EW I + K + K + Y+ I+ + ++R+PL+++I ++VP + S LA +F L +G+++T+++S+++++T+++++++ P + +P++ Y++ + L++ S +L+VV L +
Sbjct: 10 INGSRKAS-------EAERRLLEDLFQDYNLKVRPARTWN--ERVMVRVGMTLVQLISLNQKNGEMTTNVFMNMEWTDYRLSWNPEDYDKIDVVRIPPVKVWRPDIYLI---NNNDGQFDVALYVNVLVRSDGTVSWLPPAIYRSSCSIEVAYFPFDWQNCSMV---FRSYTYDSSEVDLQYGLDEDGNELHEIVIDENAFTENGEWQICH-KPSRKNVQDDL---YEDITFYLIIERKPLFYVINIIVPCILTSVLAIFVFYLPPGAGEKMTLSISVLIALTVFMLLLADKVPETSLAIPIIVNYVMFTMILVTFSVILSVVVLNLHHR 320
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Zebrafish
Match: chrnb1l (cholinergic receptor, nicotinic, beta 1 (muscle) like [Source:ZFIN;Acc:ZDB-GENE-060811-1]) HSP 1 Score: 135.191 bits (339), Expect = 1.387e-33 Identity = 85/316 (26.90%), Postives = 171/316 (54.11%), Query Frame = 1
Query: 121 EEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNI--------SEWIILYVKFNYKTYVSQINI---TYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAVVNQKLREK 1032
E +L+ L + ++LKVRP + V+V + ++Q+++ +Q + + + + W DYRL+W+P+ I V +P K+W PD+ ++ NN D F + V DG V+W+ I SC ++V+YFPFD Q C ++ ++S+ V +Q+G D + L I EW I + S+ NI Y+ I+ + ++R+PL+++I ++VP + S LA +F L +G+++T+++S+++++T+++++++ P + +P++ Y++ + L++ S +L+VV L +
Sbjct: 6 ERRLLEDLFQDYNLKVRPARTWN--ERVMVRVGMTLVQLISLNQKNGEMTTNVFMNMEWTDYRLSWNPEDYDKIDVVRIPPVKVWRPDIYLI---NNNDGQFDVALYVNVLVRSDGTVSWLPPAIYRSSCSIEVAYFPFDWQNCSMV---FRSYTYDSSEVDLQYGLDEDGNELHEIVIDENAFTENGEWQICHKP-------SRKNIQDDLYEDITFYLIIERKPLFYVINIIVPCILTSVLAIFVFYLPPGAGEKMTLSISVLIALTVFMLLLADKVPETSLAIPIIVNYVMFTMILVTFSVILSVVVLNLHHR 306
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Xenopus
Match: ncaph (non-SMC condensin I complex subunit H [Source:Xenbase;Acc:XB-GENE-5738397]) HSP 1 Score: 147.517 bits (371), Expect = 8.986e-38 Identity = 85/299 (28.43%), Postives = 160/299 (53.51%), Query Frame = 1
Query: 121 EEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVD-NSYLPNSNISEW-IILYVKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAV 1008
EEKL +L+ R++ +RP + V+V+ + Q++ + + + W W DY+L W+PK I + +P++K+W PD+ + N N DF + +S+ V ++G +TW I SCP+D+++FPFD Q C + W +I + + GS VD + N SEW I+ F + + Y I+ S ++R P+++ I +++P LS L L+F L D G+++T+ +S++LS+T+++++++ P + +P++ YLL + +++S V+ V
Sbjct: 27 EEKLFQKLLARYNQHIRPVE--NVSDPVMVHFEVAITQLVNVDEVNQILETNLWLRHIWNDYKLQWNPKEYDGIEFMRIPADKIWKPDIVLYN---NAVGDFQVEGKSKALVKYNGLITWSPPAIFKSSCPMDITFFPFDHQNCSMKFGSWSYDKAKIDLAII--GSKVDMKDFWEN---SEWEIVDASGFKHDIKYNCCEEIYTDITYSFYIRRLPMFYTINLIMPCLFLSFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLVGEYLLFTMIFVTLSIVVTV 315
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Xenopus
Match: ncaph (non-SMC condensin I complex subunit H [Source:Xenbase;Acc:XB-GENE-5738397]) HSP 1 Score: 146.747 bits (369), Expect = 1.296e-37 Identity = 85/299 (28.43%), Postives = 160/299 (53.51%), Query Frame = 1
Query: 121 EEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVD-NSYLPNSNISEW-IILYVKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAV 1008
EEKL +L+ R++ +RP + V+V+ + Q++ + + + W W DY+L W+PK I + +P++K+W PD+ + N N DF + +S+ V ++G +TW I SCP+D+++FPFD Q C + W +I + + GS VD + N SEW I+ F + + Y I+ S ++R P+++ I +++P LS L L+F L D G+++T+ +S++LS+T+++++++ P + +P++ YLL + +++S V+ V
Sbjct: 16 EEKLFQKLLARYNQHIRPVE--NVSDPVMVHFEVAITQLVNVDEVNQILETNLWLRHIWNDYKLQWNPKEYDGIEFMRIPADKIWKPDIVLYN---NAVGDFQVEGKSKALVKYNGLITWSPPAIFKSSCPMDITFFPFDHQNCSMKFGSWSYDKAKIDLAII--GSKVDMKDFWEN---SEWEIVDASGFKHDIKYNCCEEIYTDITYSFYIRRLPMFYTINLIMPCLFLSFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLVGEYLLFTMIFVTLSIVVTV 304
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Xenopus
Match: ncaph (non-SMC condensin I complex subunit H [Source:Xenbase;Acc:XB-GENE-5738397]) HSP 1 Score: 147.132 bits (370), Expect = 1.359e-37 Identity = 85/299 (28.43%), Postives = 160/299 (53.51%), Query Frame = 1
Query: 121 EEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVD-NSYLPNSNISEW-IILYVKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAV 1008
EEKL +L+ R++ +RP + V+V+ + Q++ + + + W W DY+L W+PK I + +P++K+W PD+ + N N DF + +S+ V ++G +TW I SCP+D+++FPFD Q C + W +I + + GS VD + N SEW I+ F + + Y I+ S ++R P+++ I +++P LS L L+F L D G+++T+ +S++LS+T+++++++ P + +P++ YLL + +++S V+ V
Sbjct: 34 EEKLFQKLLARYNQHIRPVE--NVSDPVMVHFEVAITQLVNVDEVNQILETNLWLRHIWNDYKLQWNPKEYDGIEFMRIPADKIWKPDIVLYN---NAVGDFQVEGKSKALVKYNGLITWSPPAIFKSSCPMDITFFPFDHQNCSMKFGSWSYDKAKIDLAII--GSKVDMKDFWEN---SEWEIVDASGFKHDIKYNCCEEIYTDITYSFYIRRLPMFYTINLIMPCLFLSFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLVGEYLLFTMIFVTLSIVVTV 322
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Xenopus
Match: ncaph (non-SMC condensin I complex subunit H [Source:Xenbase;Acc:XB-GENE-5738397]) HSP 1 Score: 146.362 bits (368), Expect = 2.272e-37 Identity = 85/299 (28.43%), Postives = 160/299 (53.51%), Query Frame = 1
Query: 121 EEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVD-NSYLPNSNISEW-IILYVKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAV 1008
EEKL +L+ R++ +RP + V+V+ + Q++ + + + W W DY+L W+PK I + +P++K+W PD+ + N N DF + +S+ V ++G +TW I SCP+D+++FPFD Q C + W +I + + GS VD + N SEW I+ F + + Y I+ S ++R P+++ I +++P LS L L+F L D G+++T+ +S++LS+T+++++++ P + +P++ YLL + +++S V+ V
Sbjct: 22 EEKLFQKLLARYNQHIRPVE--NVSDPVMVHFEVAITQLVNVDEVNQILETNLWLRHIWNDYKLQWNPKEYDGIEFMRIPADKIWKPDIVLYN---NAVGDFQVEGKSKALVKYNGLITWSPPAIFKSSCPMDITFFPFDHQNCSMKFGSWSYDKAKIDLAII--GSKVDMKDFWEN---SEWEIVDASGFKHDIKYNCCEEIYTDITYSFYIRRLPMFYTINLIMPCLFLSFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLVGEYLLFTMIFVTLSIVVTV 310
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Xenopus
Match: ncaph (non-SMC condensin I complex subunit H [Source:Xenbase;Acc:XB-GENE-5738397]) HSP 1 Score: 146.362 bits (368), Expect = 2.310e-37 Identity = 85/299 (28.43%), Postives = 160/299 (53.51%), Query Frame = 1
Query: 121 EEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVD-NSYLPNSNISEW-IILYVKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAV 1008
EEKL +L+ R++ +RP + V+V+ + Q++ + + + W W DY+L W+PK I + +P++K+W PD+ + N N DF + +S+ V ++G +TW I SCP+D+++FPFD Q C + W +I + + GS VD + N SEW I+ F + + Y I+ S ++R P+++ I +++P LS L L+F L D G+++T+ +S++LS+T+++++++ P + +P++ YLL + +++S V+ V
Sbjct: 21 EEKLFQKLLARYNQHIRPVE--NVSDPVMVHFEVAITQLVNVDEVNQILETNLWLRHIWNDYKLQWNPKEYDGIEFMRIPADKIWKPDIVLYN---NAVGDFQVEGKSKALVKYNGLITWSPPAIFKSSCPMDITFFPFDHQNCSMKFGSWSYDKAKIDLAII--GSKVDMKDFWEN---SEWEIVDASGFKHDIKYNCCEEIYTDITYSFYIRRLPMFYTINLIMPCLFLSFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLVGEYLLFTMIFVTLSIVVTV 309
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Mouse
Match: Chrna3 (cholinergic receptor, nicotinic, alpha polypeptide 3 [Source:MGI Symbol;Acc:MGI:87887]) HSP 1 Score: 138.658 bits (348), Expect = 8.527e-35 Identity = 78/298 (26.17%), Postives = 156/298 (52.35%), Query Frame = 1
Query: 121 EEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYVK-FNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAV 1008
E +L L + ++ +RP A + VI+ ++ Q++ + + + W W DY+L W P + + +P+EK+W PD+ + N N D DF +++ + + G VTW+ I SC +DV+YFPFD Q C + W +I +V + + + + EW I+ + ++ + YQ I+ S+ ++R PL++ I +++P ++S L L+F L D G+++T+ +S++LS+T+++++++ P + +P++ YLL + +++S V+ V
Sbjct: 29 EHRLFQYLFEDYNEIIRPVA--NVSHPVIIQFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWKPSDYQGVEFMRVPAEKIWKPDIVLYN---NADGDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYW----ESGEWAIIKAPGYKHEIKYNCCEEIYQDITYSLYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITV 317
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Mouse
Match: Chrna6 (cholinergic receptor, nicotinic, alpha polypeptide 6 [Source:MGI Symbol;Acc:MGI:106213]) HSP 1 Score: 139.043 bits (349), Expect = 1.042e-34 Identity = 82/310 (26.45%), Postives = 159/310 (51.29%), Query Frame = 1
Query: 88 AGFHDYSSFGDEEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVD-NSYLPNSNISEW-IILYVKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAV 1008
A F + EE+L +L ++ +RP + V V+ + Q+ + + + W W+DYRL W P I + +P++ +W PD+ + N N DF + +++ + +DG +TW I SCP+D+++FPFD Q C + W +I ++ + GS VD N + N SEW I+ + + + Y I+ S ++R P+++ I +++P +S L L+F L D G+++T+ +S++LS+T+++++++ P + +P++ YLL + +++S V+ V
Sbjct: 23 ALFKGSTGCESEEQLFHRLFAHYNRFIRPVE--NVSDPVTVHFELAITQLANVDEVNQIMETNLWLRHIWKDYRLRWDPTEYDGIETLRVPADNIWKPDIVLYN---NAVGDFQVEGKTKALLKYDGVITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLII--GSKVDMNDFWEN---SEWEIVDASGYKHDIKYNCCEEIYTDITYSFYIRRLPMFYTINLIIPCLFISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLVGEYLLFTMIFVTLSIVVTV 322
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Mouse
Match: Chrna3 (cholinergic receptor, nicotinic, alpha polypeptide 3 [Source:MGI Symbol;Acc:MGI:87887]) HSP 1 Score: 138.658 bits (348), Expect = 1.345e-34 Identity = 78/298 (26.17%), Postives = 156/298 (52.35%), Query Frame = 1
Query: 121 EEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYVK-FNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAV 1008
E +L L + ++ +RP A + VI+ ++ Q++ + + + W W DY+L W P + + +P+EK+W PD+ + N N D DF +++ + + G VTW+ I SC +DV+YFPFD Q C + W +I +V + + + + EW I+ + ++ + YQ I+ S+ ++R PL++ I +++P ++S L L+F L D G+++T+ +S++LS+T+++++++ P + +P++ YLL + +++S V+ V
Sbjct: 29 EHRLFQYLFEDYNEIIRPVA--NVSHPVIIQFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWKPSDYQGVEFMRVPAEKIWKPDIVLYN---NADGDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYW----ESGEWAIIKAPGYKHEIKYNCCEEIYQDITYSLYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITV 317
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Mouse
Match: Chrna3 (cholinergic receptor, nicotinic, alpha polypeptide 3 [Source:MGI Symbol;Acc:MGI:87887]) HSP 1 Score: 138.658 bits (348), Expect = 1.379e-34 Identity = 78/298 (26.17%), Postives = 156/298 (52.35%), Query Frame = 1
Query: 121 EEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYVK-FNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAV 1008
E +L L + ++ +RP A + VI+ ++ Q++ + + + W W DY+L W P + + +P+EK+W PD+ + N N D DF +++ + + G VTW+ I SC +DV+YFPFD Q C + W +I +V + + + + EW I+ + ++ + YQ I+ S+ ++R PL++ I +++P ++S L L+F L D G+++T+ +S++LS+T+++++++ P + +P++ YLL + +++S V+ V
Sbjct: 34 EHRLFQYLFEDYNEIIRPVA--NVSHPVIIQFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWKPSDYQGVEFMRVPAEKIWKPDIVLYN---NADGDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYW----ESGEWAIIKAPGYKHEIKYNCCEEIYQDITYSLYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITV 322
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Mouse
Match: Chrnd (cholinergic receptor, nicotinic, delta polypeptide [Source:MGI Symbol;Acc:MGI:87893]) HSP 1 Score: 135.576 bits (340), Expect = 2.102e-33 Identity = 88/316 (27.85%), Postives = 162/316 (51.27%), Query Frame = 1
Query: 109 SFGDEEKLITQLM--KRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNI----------SEWIILY--VKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAVV 1011
+E++LI L K + +RP A + V V ++ + +++ + EET + + W W D RL W GNIT + LP + +WLP++ + NN D F + V G+VTW+ I SCP+ V+YFPFD Q C + + + K+I + Q +N P I EW I++ K N V + +Q ++ + ++R+PL++II +LVP ++S + L+F L D G++ +VA+S++L+ +++++++S P + +P++ +LL + L+++ V+ V+
Sbjct: 24 GLNEEQRLIQHLFNEKGYDKDLRPVA--RKEDKVDVALSLTLSNLISLKEVEETLTTNVWIDHAWVDSRLQWDANDFGNITVLRLPPDMVWLPEIVL---ENNNDGSFQISYACNVLVYDSGYVTWLPPAIFRSSCPISVTYFPFDWQNCSLKFSSLKYTAKEITLSLKQEEE--NNRSYPIEWIIIDPEGFTENGEWEIVHRAAKLNVDPSVPMDSTNHQDVTFYLIIRRKPLFYIINILVPCVLISFMINLVFYLPGDCGEKTSVAISVLLAQSVFLLLISKRLPATSMAIPLVGKFLLFGMVLVTMVVVICVI 332
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. UniProt/SwissProt
Match: sp|P17644|ACH2_DROME (Acetylcholine receptor subunit alpha-like 2 OS=Drosophila melanogaster OX=7227 GN=nAChRalpha2 PE=2 SV=1) HSP 1 Score: 147.902 bits (372), Expect = 1.783e-36 Identity = 86/309 (27.83%), Postives = 161/309 (52.10%), Query Frame = 1
Query: 118 DEEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDN---------SYLPNSNISEWIILYVKFN-YKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTLD-DSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAVV 1011
D ++L L+ ++ +RP + T V+V + + Q++ + ++ + + W WQD++ W P G +T++++PSE +WLPD+ + NN D ++ + ++ + + G V W I SC +DV YFPFD QTC++ W QI + + + DN Y P+ EW IL V ++ Y Y I +I ++R+ L++ + +++P +S L+ L+F L DSG+++ + +S++LS TM+ +++S P + LP+L YLL + L+ +S V+ ++
Sbjct: 44 DAKRLYDDLLSNYNRLIRPVS--NNTDTVLVKLGLRLSQLIDLNLKDQILTTNVWLEHEWQDHKFKWDPSEYGGVTELYVPSEHIWLPDIVLY---NNADGEYVVTTMTKAILHYTGKVVWTPPAIFKSSCEIDVRYFPFDQQTCFMKFGSWTYDGDQIDLKHISQKNDKDNKVEIGIDLREYYPS---VEWDILGVPAERHEKYYPCCAEPYPDIFFNITLRRKTLFYTVNLIIPCVGISYLSVLVFYLPADSGEKIALCISILLSQTMFFLLISEIIPSTSLALPLLGKYLLFTMLLVGLSVVITII 344
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. UniProt/SwissProt
Match: sp|P25110|ACHD_RAT (Acetylcholine receptor subunit delta OS=Rattus norvegicus OX=10116 GN=Chrnd PE=1 SV=1) HSP 1 Score: 145.206 bits (365), Expect = 7.802e-36 Identity = 92/316 (29.11%), Postives = 167/316 (52.85%), Query Frame = 1
Query: 109 SFGDEEKLITQLM--KRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNI----------SEWIILY--VKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAVV 1011
+E++LI L K ++ ++RP A + V V ++ + +++ + EET + + W W D RL W+ GNIT + LPS+ +WLP++ + NN D F + VS GHVTW+ I SCP+ V+YFPFD Q C + + + K+I + Q DN P I EW I++ K N V + +Q ++ + ++R+PL++II +LVP ++S + L+F L D G++ +VA+S++L+ +++++++S P + +P++ +LL + L+++ V+ V+
Sbjct: 21 GLNEEQRLIQHLFEEKGYNKELRPVA--RKEDIVDVALSLTLSNLISLKEVEETLTTNVWIDHAWIDSRLQWNANEFGNITVLRLPSDMVWLPEIVL---ENNNDGSFQISYACNVLVSDSGHVTWLPPAIFRSSCPISVTYFPFDWQNCSLKFSSLKYTAKEIRLSLKQEEE--DNRSYPIEWIIIDPEGFTENGEWEIVHRAAKVNVDPSVPMDSTNHQDVTFYLIIRRKPLFYIINILVPCVLISFMINLVFYLPGDCGEKTSVAISVLLAQSVFLLLISKRLPATSMAIPLVGKFLLFGMVLVTMVVVICVI 329
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. UniProt/SwissProt
Match: sp|P23414|ACH1_SCHGR (Acetylcholine receptor subunit alpha-L1 OS=Schistocerca gregaria OX=7010 PE=2 SV=1) HSP 1 Score: 145.206 bits (365), Expect = 1.104e-35 Identity = 88/309 (28.48%), Postives = 160/309 (51.78%), Query Frame = 1
Query: 118 DEEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDN---------SYLPNSNISEWIILYVKFN-YKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTLD-DSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAVV 1011
D ++L L+ ++ +RP + T V+V + + Q++ + ++ + + W WQD++ W P G +T++++PSE +WLPD+ + NN D ++ + ++ + H G V W I SC +DV YFPFD QTC++ W QI + + DN Y P+ EW IL V ++ Y Y I +I ++R+ L++ + ++VP +S L+ L+F L DSG+++ + +S++LS TM+ +++S P + LP+L YLL + L+ +S V+ ++
Sbjct: 26 DAKRLYDDLLSNYNRLIRPVS--NNTDTVLVKLGLRLSQLIDLNLKDQILTTNVWLEHEWQDHKFRWDPAEYGGVTELYVPSEHIWLPDIVLY---NNADGEYVVTTMTKAVLHHTGKVVWTPPAIFKSSCEIDVRYFPFDQQTCFMKFGSWTYDGDQIDLKHINQKYD-DNKVKVGIDLREYYPS---VEWDILGVPAERHEKYYPCCAEPYPDIFFNITLRRKTLFYTVNLIVPCVGISYLSVLVFYLPADSGEKIALCISILLSQTMFFLLISEIIPSTSLALPLLGKYLLFTMVLVGLSVVITIM 325
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. UniProt/SwissProt
Match: sp|P05376|ACHG_XENLA (Acetylcholine receptor subunit gamma OS=Xenopus laevis OX=8355 GN=chrng PE=2 SV=1) HSP 1 Score: 142.51 bits (358), Expect = 5.245e-35 Identity = 92/315 (29.21%), Postives = 170/315 (53.97%), Query Frame = 1
Query: 118 DEEKLITQLMKRHSLKVRPTACFQCTGAVI-VNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIIL---TPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYVK----FNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL--DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYL--LNQLGLLSVSTVLAVVNQKLR 1026
+EE+L+ LMK ++ +RP + G +I V+I + +++ ++ EE + + W + W+DYRL+W P I+ + +PS +WLPDVG+ NN D F + VS DG + W+ I SCP+ V+YFPFD Q C I+ T + ++ +L V Q ++ + EW I ++ N++ +N YQ I + +QR+PL++II ++VP ++S ++ L++ L G + TV+++++L+ T+++ +V+ P + ++P++ YL L + + V+ + V+N LR
Sbjct: 20 EEERLLNDLMKNYNKNLRPV---EKDGDIISVSIKLTLTNLISLNEKEEALTTNVWVEMQWKDYRLSWDPNDYHGISMMRIPSTSVWLPDVGL---ENNVDGTFDIALYTNTLVSSDGSMYWLPPAIYRSSCPVVVTYFPFDWQNCSIVFQSQTYSANEIELLLTVDEQTIEWIEIDPEAFTENGEWAIKHMPAKRIINHRLPRDDVN--YQQIVFYLIIQRKPLFYIINIIVPCVLISFVSILVYFLPAKAGGQKCTVSINILLAQTVFLFLVAQKIPETSTSVPLIVKYLTFLMVVTITIVANAVIVLNISLR 326
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. UniProt/SwissProt
Match: sp|P43143|ACHA6_RAT (Neuronal acetylcholine receptor subunit alpha-6 OS=Rattus norvegicus OX=10116 GN=Chrna6 PE=2 SV=1) HSP 1 Score: 140.198 bits (352), Expect = 2.358e-34 Identity = 88/333 (26.43%), Postives = 170/333 (51.05%), Query Frame = 1
Query: 19 MLNVFGKFEIVAILSIFINSSRGAGFHDYSSFGDEEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVD-NSYLPNSNISEW-IILYVKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAV 1008
MLN +G+ ++ + L ++I A F EE+L L ++ +RP + V V+ + Q+ + + + W W+DYRL W P I + +P++ +W PD+ + N N DF + +++ + +DG +TW I SCP+D+++FPFD Q C + W +I ++ + GS VD N + N SEW I+ + + + Y I+ S ++R P+++ I +++P +S L L+F L D G+++T+ +S++LS+T+++++++ P + +P++ YLL + +++S V+ V
Sbjct: 1 MLNGWGRGDLRSGLCLWI-CGFLAFFKGSRGCVSEEQLFHTLFAHYNRFIRPVE--NVSDPVTVHFELAITQLANVDEVNQIMETNLWLRHVWKDYRLCWDPTEYDGIETLRVPADNIWKPDIVLYN---NAVGDFQVEGKTKALLKYDGVITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLII--GSKVDMNDFWEN---SEWEIVDASGYKHDIKYNCCEEIYTDITYSFYIRRLPMFYTINLIIPCLFISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLVGEYLLFTMIFVTLSIVVTV 322
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. TrEMBL
Match: A0A4S2MMC4 (Neur_chan_LBD domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_000207 PE=3 SV=1) HSP 1 Score: 439.499 bits (1129), Expect = 1.164e-141 Identity = 205/319 (64.26%), Postives = 256/319 (80.25%), Query Frame = 1
Query: 106 SSFGDEEKLITQLMKRHSLKVRPTACF-QCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYVKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTLDDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAVVNQKLREKYRLSFWQDY 1059
+ EEKL+ QL+ R SL VRP + T V V+ITYNVIQILAFSQAEET SISGWFT+ W+D RL W P+ +I +V +PS +LW+PDVGVMNG+++ DFDFSA + R+++S G VTW+HG +LD +CPLDV++FPFD QTC++ILTPWQS+ +Q+L+ P HGS VDNSYLPNSN+SEW I V F+ + Y S +N+TYQY+SI I ++RQPLYF++LVLVPFSMLS LACLIFTLDD+GDRL+VALSLVLSMTMYVVIVS+NAPRSMR LPVL I+LL+QLGLLS++TVLAV+N KL + L WQD+
Sbjct: 10 GTLSAEEKLVAQLLNRGSLTVRPNGHNNKTTSPVFVDITYNVIQILAFSQAEETMSISGWFTIKWRDPRLTWDPQEFSDIAEVNVPSGQLWIPDVGVMNGKSSTDFDFSAGVRGRLTLSSQGEVTWLHGAVLDTTCPLDVAFFPFDYQTCFLILTPWQSNEQQLLLRPFTHGSAVDNSYLPNSNVSEWEIQSVHFSSRKYRSDLNVTYQYVSIGIHLRRQPLYFVVLVLVPFSMLSALACLIFTLDDTGDRLSVALSLVLSMTMYVVIVSTNAPRSMRTLPVLGIFLLDQLGLLSIATVLAVINNKLYQATELMSWQDW 328
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. TrEMBL
Match: A0A504YDR0 (Putative nachr subunit OS=Fasciola gigantica OX=46835 GN=FGIG_03463 PE=3 SV=1) HSP 1 Score: 440.269 bits (1131), Expect = 4.911e-141 Identity = 211/318 (66.35%), Postives = 255/318 (80.19%), Query Frame = 1
Query: 109 SFGDEEKLITQLMKRHSLKVRPTACF-QCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYVKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTLDDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAVVNQKLREKYRLSFWQDY 1059
+F EE+L+ QL+ R SL VRP Q + V VNITYNV+QILAFSQAEET SISGWFT+ W D RL+W P NI +V +PS KLW+PDVGVMNG+++ DFDFSA + R++V+ +G VTWMHG +LD +CPLDVS+FPFD QTC++ILTPWQS +Q+L+ P HGS VDNSYLPNSN+SEW I V F+ K Y S +N+TYQY+SI I ++RQPLYF++LVLVPFSMLS LACLIFTLDD+GDRL+VALSLVLSMTMYVVIVSSNAPRSMR LPVL I+LL+QLGLLSV+TVLAV+N KL L W+D+
Sbjct: 91 TFMPEERLVAQLLHRRSLVVRPNGHNNQSSNPVHVNITYNVVQILAFSQAEETLSISGWFTIKWTDPRLSWDPHAFDNIREVNVPSSKLWIPDVGVMNGKSSTDFDFSAGVRGRLTVNWEGEVTWMHGAVLDTTCPLDVSFFPFDYQTCFLILTPWQSSEQQLLLRPFSHGSAVDNSYLPNSNVSEWEIQSVHFSSKKYRSDLNVTYQYVSIGIHLKRQPLYFVVLVLVPFSMLSALACLIFTLDDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRTLPVLGIFLLDQLGLLSVATVLAVINNKLFSSDELINWKDW 408
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. TrEMBL
Match: V9TKF5 (Nicotinic acetylcholine receptor OS=Schistosoma mansoni OX=6183 PE=2 SV=1) HSP 1 Score: 442.195 bits (1136), Expect = 5.399e-141 Identity = 210/318 (66.04%), Postives = 253/318 (79.56%), Query Frame = 1
Query: 109 SFGDEEKLITQLMKRHSLKVRPTACF-QCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYVKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTLDDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAVVNQKLREKYRLSFWQDY 1059
SF EEKL+ QL+ R SL VRP Q T V VNITYNV+QIL FSQ+EET SISGWFT+ W D RL W P+ I +V LP+ LW+PDVGVMNG+ + DFDFSA + R++VS+DG VTW+HG +LDV+CPLDVS+FPFD QTC++IL PWQS +Q+L+ P HGS VDNSYLPNSN+SEW I V F K Y S +N+TYQY+SI+I ++RQPLYFI+LVLVPFSMLS LACLIFTLDD+GDRL+VALSLVLSMTMYVVIVS+NAPRSMR LPVL I+LL+QLGLLS++T+LAV+N KL + L WQD+
Sbjct: 86 SFTAEEKLVAQLLNRGSLTVRPNGYMNQSTNPVHVNITYNVVQILGFSQSEETLSISGWFTMRWTDPRLTWDPEEFSEIQEVSLPTTNLWIPDVGVMNGKASTDFDFSAGVRGRVTVSNDGSVTWLHGAVLDVTCPLDVSFFPFDYQTCFLILVPWQSGEQQLLLQPFTHGSAVDNSYLPNSNVSEWEIQSVHFVRKKYRSDMNVTYQYVSIAIHLKRQPLYFIVLVLVPFSMLSALACLIFTLDDTGDRLSVALSLVLSMTMYVVIVSTNAPRSMRTLPVLGIFLLDQLGLLSIATILAVMNNKLYQSTELLNWQDF 403
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. TrEMBL
Match: A0A4E0RUV1 (Neuronal acetylcholine receptor subunit alpha-6 OS=Fasciola hepatica OX=6192 GN=D915_003262 PE=3 SV=1) HSP 1 Score: 439.884 bits (1130), Expect = 5.734e-141 Identity = 211/318 (66.35%), Postives = 255/318 (80.19%), Query Frame = 1
Query: 109 SFGDEEKLITQLMKRHSLKVRPTACF-QCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYVKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTLDDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAVVNQKLREKYRLSFWQDY 1059
+F EE+L+ QL+ R SL VRP Q + V VNITYNV+QILAFSQAEET SISGWFT+ W D RL+W P NI +V +PS KLW+PDVGVMNG+++ DFDFSA + R++V+ +G VTWMHG +LD +CPLDVS+FPFD QTC++ILTPWQS +Q+L+ P HGS VDNSYLPNSN+SEW I V F+ K Y S +N+TYQY+SI I ++RQPLYF++LVLVPFSMLS LACLIFTLDD+GDRL+VALSLVLSMTMYVVIVSSNAPRSMR LPVL I+LL+QLGLLSV+TVLAV+N KL L W+D+
Sbjct: 91 TFMPEERLVAQLLHRRSLVVRPNGHNNQSSNPVHVNITYNVVQILAFSQAEETLSISGWFTIKWTDPRLSWDPHAFDNIREVNVPSSKLWIPDVGVMNGKSSTDFDFSAGVRGRLTVNWEGEVTWMHGAVLDTTCPLDVSFFPFDYQTCFLILTPWQSSEQQLLLRPFSHGSAVDNSYLPNSNVSEWEIQSVHFSSKKYRSDLNVTYQYVSIGIHLKRQPLYFVVLVLVPFSMLSALACLIFTLDDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRTLPVLGIFLLDQLGLLSVATVLAVINNKLFSSDELINWKDW 408
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. TrEMBL
Match: A0A3Q0KCD0 (Acetylcholine receptor-related OS=Schistosoma mansoni OX=6183 PE=3 SV=1) HSP 1 Score: 442.195 bits (1136), Expect = 8.548e-141 Identity = 210/318 (66.04%), Postives = 253/318 (79.56%), Query Frame = 1
Query: 109 SFGDEEKLITQLMKRHSLKVRPTACF-QCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYVKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTLDDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAVVNQKLREKYRLSFWQDY 1059
SF EEKL+ QL+ R SL VRP Q T V VNITYNV+QIL FSQ+EET SISGWFT+ W D RL W P+ I +V LP+ LW+PDVGVMNG+ + DFDFSA + R++VS+DG VTW+HG +LDV+CPLDVS+FPFD QTC++IL PWQS +Q+L+ P HGS VDNSYLPNSN+SEW I V F K Y S +N+TYQY+SI+I ++RQPLYFI+LVLVPFSMLS LACLIFTLDD+GDRL+VALSLVLSMTMYVVIVS+NAPRSMR LPVL I+LL+QLGLLS++T+LAV+N KL + L WQD+
Sbjct: 101 SFTAEEKLVAQLLNRGSLTVRPNGYMNQSTNPVHVNITYNVVQILGFSQSEETLSISGWFTMRWTDPRLTWDPEEFSEIQEVSLPTTNLWIPDVGVMNGKASTDFDFSAGVRGRVTVSNDGSVTWLHGAVLDVTCPLDVSFFPFDYQTCFLILVPWQSGEQQLLLQPFTHGSAVDNSYLPNSNVSEWEIQSVHFVRKKYRSDMNVTYQYVSIAIHLKRQPLYFIVLVLVPFSMLSALACLIFTLDDTGDRLSVALSLVLSMTMYVVIVSTNAPRSMRTLPVLGIFLLDQLGLLSIATILAVMNNKLYQSTELLNWQDF 418
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Cavefish
Match: chrnb1l (acetylcholine receptor subunit beta-like [Source:NCBI gene;Acc:103034907]) HSP 1 Score: 138.272 bits (347), Expect = 1.334e-34 Identity = 85/313 (27.16%), Postives = 169/313 (53.99%), Query Frame = 1
Query: 121 EEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNI--------SEWIILYVKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAVVNQKLREK 1032
E L+ L + +++KVRP + T V+V + ++Q+++ Q + + + + W DYRL+W+P NI + +P K+W PD+ ++ NN D F + V+ DG V+W+ I SC ++V+YFPFD Q C ++ +S+ V +Q+G D + L I EW I + K K + Y+ I+ + ++R+PL++II ++VP + S LA +F L +G+++T+++S+++++T+++++++ P + +P++ Y++ + L++ S +L+VV L +
Sbjct: 27 ERSLLQDLFENYNVKVRPARVWNET--VMVRVGMTLVQLISLDQKNGEMTTNVYMNMAWTDYRLSWNPADYDNIDVIRIPPTKVWRPDIYLI---NNNDGQFDVALYVNVLVNSDGTVSWLPPAIYRSSCSIEVAYFPFDWQNCTMVF---RSYTYDASEVDLQYGLDEDGNELHEIVIDKNAFTENGEWQICH-KPTRKNIQEDL---YEDITFYLIIERKPLFYIINIIVPCILTSVLAIFVFYLPPGAGEKMTLSISVLIALTVFMLLLADKVPETSLAIPIIVNYVMFTMILVTFSVILSVVVLNLHHR 327
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Cavefish
Match: chrna3 (neuronal acetylcholine receptor subunit alpha-3-like [Source:NCBI gene;Acc:103025148]) HSP 1 Score: 135.191 bits (339), Expect = 1.120e-33 Identity = 85/317 (26.81%), Postives = 164/317 (51.74%), Query Frame = 1
Query: 64 IFINSSRGAGFHDYSSFGDEEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYVK-FNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAV 1008
IFI S G + E +L + + ++ +RP + VIV ++ Q++ + + + W W DY+L W PK G + + +PS ++W PD+ + NN DF +++ + ++G VTW+ I SC +DV+YFPFD Q C + W +I +V + GST++ S EW+I+ + + + Y I+ S+ ++R PL++ I +++P ++S L L+F L D G+++T+ +S++LS+T+++++++ P + +P++ YLL + +++S V+ V
Sbjct: 11 IFICFSAGGWASE-----AEHRLFSVIFSSYNQYIRPVE--NVSDPVIVQFEVSMSQLVKVDEVNQIMETNLWLRHIWNDYKLRWDPKDFGGVEFIRVPSNRIWKPDIVL---YNNAVGDFQVDDKTKALLRYNGDVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWTYDKAKIDLVLI--GSTINLKDFWESG--EWMIIDAPGYKHDIKYNCCEEIYTDITYSLYIRRLPLFYTINMIIPCLLISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITV 313
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Cavefish
Match: chrne (acetylcholine receptor subunit gamma-like [Source:NCBI gene;Acc:103030399]) HSP 1 Score: 135.576 bits (340), Expect = 1.415e-33 Identity = 85/318 (26.73%), Postives = 162/318 (50.94%), Query Frame = 1
Query: 109 SFGDEEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGST------VDNSYLPNSNISEWIILY--VKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL--DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGL--LSVSTVLAVVNQKLR 1026
S +E KLI K ++ +RP V V + + +++ ++ EET + + W + W DYRL W+ +I+ + +P +WLPD+ + NN D F + + + DG + W+ I +C ++++YFPFD Q C ++ +I M+ G T VD + EW I + + T S ++ YQ + ++ +QR+PL++II +++P +++S L L + L G +LTV++S++L+ T+++++VS P + ++P++ YL+ + + L V+ + V+N LR
Sbjct: 25 SGNEESKLIADKFKNYNKNIRPAR--HTEDKVQVQVKLTLTNLISLNEKEETLTTNVWIEIQWNDYRLAWNTSDYHDISLIRVPYNTVWLPDIVL---ENNIDGKFDVAYYANVLIYSDGSMYWLPPAIYRSTCAIEITYFPFDWQNCTLVFRSQTYSANEIDMILAIDGDTQKPIEWVDIDPEAFTENGEWAIKHRPARKLTNTRYSPDDLEYQEVYFNLIIQRKPLFYIINIILPCALISSLVVLAYFLPAQAGGQKLTVSISVLLAQTVFLILVSQKVPETSLSVPLIGKYLIFVMSVTTLIVTNCIVVLNFSLR 337
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Cavefish
Match: chrna4b (neuronal acetylcholine receptor subunit alpha-2 [Source:NCBI gene;Acc:103025036]) HSP 1 Score: 136.346 bits (342), Expect = 1.734e-33 Identity = 90/335 (26.87%), Postives = 175/335 (52.24%), Query Frame = 1
Query: 70 INSSRGAGFHD-YSSFGDEEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYV--KFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAV----VNQKLREKYRLSFW 1050
I ++ G+G +S EE+L+ L R++ RP A + V+V+ ++ Q++ + + + + W W DY+L W+P+ N+T + +PSE +W PD+ + NN D DF+ ++ + HDG + W I SC +DV++FPFD Q C + W +I +V + D + EW+I+ K+N K Y I Y I+ S ++R PL++ I +++P ++S L L+F L + +++T+ +S++LS+T+++++++ P + +P++ YLL + +++S ++ V V+ + +R+ W
Sbjct: 10 IQANVGSGMITIHSRAHAEERLLQVLFSRYNKLSRPVA--NISDVVLVHFGLSIAQLIDVDEKNQMMTTNVWVKQEWSDYKLRWNPEEYENVTSIRIPSELIWRPDIVLY---NNADGDFAVTHLTKAQLFHDGRIKWKPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDRAKIDLVSMDD----DVDQMDYWESGEWVIINAVGKYNTKKYECCTEI-YPDITYSFIIRRLPLFYTINLIIPCLLISCLTVLVFYLPSECAEKITLCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMIFVTLSIIITVFVLNVHHRSSRTHRMPHW 334
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Cavefish
Match: chrnb2 (cholinergic receptor nicotinic beta 2 subunit [Source:NCBI gene;Acc:103045386]) HSP 1 Score: 135.961 bits (341), Expect = 1.809e-33 Identity = 92/327 (28.13%), Postives = 176/327 (53.82%), Query Frame = 1
Query: 46 IVAILSIFINSSRGAGFHDYSSFGDEEKLITQLM--KRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYVKFNYKTYVSQ---INITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAV 1008
+ +L + SSRGA EE+L+ L+ ++ +RP + V V + ++ Q+++ + E+ + + W T WQDYRL W P+ + +V LPS+ +WLPDV + NN D + S VSHDG V W+ I +C ++V +FPFD Q C + W ++ +V +++D+ + P+ EW I+ + S ++ITY +I ++R+PL++ I +++P +++ LA L+F L D G+++T+ +S++L++T++++++S P + ++P++ YL+ + L++ S V +V
Sbjct: 7 LCILLLAIVQSSRGAD--------TEERLVEHLLNPAHYNKLIRPAT--NGSELVTVQLMVSLAQLISVHEREQIMTTNVWLTQEWQDYRLTWIPEEFDGMKKVRLPSKHIWLPDVVLY---NNADGMYEVSFYSNAVVSHDGSVFWLPPAIYKSACKIEVKHFPFDQQNCTLSFRSWTYDRTEVDLVLRSDVASMDD-FTPS---GEWDIIALPGRRNENPSDPTYVDITYDFI-----IRRKPLFYTINLIIPCVLITSLAILVFYLPSDCGEKMTLCISVLLALTVFLLLISKIVPPTSLDVPLVGKYLMFTMVLVTFSIVTSV 311
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Sea Lamprey
Match: chrna3 (cholinergic receptor, nicotinic, alpha 3 [Source:ZFIN;Acc:ZDB-GENE-070822-1]) HSP 1 Score: 140.969 bits (354), Expect = 2.960e-36 Identity = 85/314 (27.07%), Postives = 168/314 (53.50%), Query Frame = 1
Query: 127 KLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYVK-FNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAV----VNQKLREKYRLSFW 1050
+L L ++ +RP F + VIV ++ Q++ + + + + W TW DY+ W+P + + + +PS+K+W PD+ + NN D DF + +++ + +DG V WM I SC +DV+YFPFD Q C + W +I +V V G+ ++ S EW+I+ V + + + Y I+ S+ V+R PL++ I +++P ++S L L+F L D G+++T+++S++LS+T+++++++ P + +P++ YLL + +++S V+ + V+ + E + + W
Sbjct: 10 RLYKTLFTSYNPYIRPV--FNVSDPVIVRFEVSMSQLVKLDEVNQIMATNLWLKHTWNDYKFQWNPGQFEGMEYIRVPSDKIWKPDIVL---YNNADGDFQVEGKTKALLKYDGTVMWMPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWTYDKAKIDLVLV--GTKINLKDFWESG--EWVIIDVPGYKHDIKYNCCEQIYPDITYSVYVRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCGEKVTLSISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITIFVLNVHYRTPEAHTMPNW 314
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Sea Lamprey
Match: chrnb3b (cholinergic receptor, nicotinic, beta 3b (neuronal) [Source:ZFIN;Acc:ZDB-GENE-030102-4]) HSP 1 Score: 130.183 bits (326), Expect = 1.060e-32 Identity = 79/301 (26.25%), Postives = 148/301 (49.17%), Query Frame = 1
Query: 121 EEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPW--QSHVKQILMV--PVQHGSTVDNSYLPNSNISEWIILYVKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAV 1008
E++L+ +++K + VRP + + V V + Q++ + + + + W W D L W+P G I + +P+ +WLPD+ + + N D F ++ V HDG + W I SC +DV++FPFD Q C + W + ++MV V G DN EW L N + Y YI+ S ++R PL++ + ++VP LS L +F L D G+++++ S+++S+T++++++ P S + +P++ YLL + +++S ++ V
Sbjct: 35 EDRLLKRMLKDYQKWVRPVD--KLSDTVEVKFGLGIAQLVDVDEKNQLMTTNVWLKQEWVDINLRWNPDDYGGINSIRVPASSIWLPDIVLYD---NADGRFEGSIVTKAVVKHDGRIKWTPPAIYKSSCTIDVTFFPFDQQNCSMKFGSWTYDGTLVDLIMVNSDVDRGEYFDN--------GEWEFLNATGNKGVRLDGHRF-YPYITYSFVIRRLPLFYTLFLIVPCLGLSFLTVFVFYLPSDEGEKISLCTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLLFIMIFVTLSIIITV 321
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Sea Lamprey
Match: chrna2a (cholinergic receptor, nicotinic, alpha 2a (neuronal) [Source:ZFIN;Acc:ZDB-GENE-040108-2]) HSP 1 Score: 118.242 bits (295), Expect = 2.697e-28 Identity = 72/246 (29.27%), Postives = 133/246 (54.07%), Query Frame = 1
Query: 280 WFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYV--KFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAV 1008
W W DY+L W P N+T + +PSE +W+PD+ + N N D DF+ ++ + H G V W I SC +DV++FPFD Q C + W +I +V + + + + EW I++ +N K Y + Y I+ S ++R PL++ I +++P ++S L L+F L D G+++T+ +S++LS+T+++++++ P + +P++ YLL + +++S V+ V
Sbjct: 25 WLKQEWDDYKLQWDPAEYENVTSIRVPSELIWVPDIVLYN---NADGDFAVTHMTKAHLFHTGRVRWKPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVSMARDVDLKDYW----ESGEWAIVHAVGTYNTKKYDCCPQV-YPDITYSFIIRRLPLFYTINLIIPCLLISCLTVLVFYLPSDCGEKITLCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMIFVTLSIVITV 262
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Sea Lamprey
Match: chrnb1l (cholinergic receptor, nicotinic, beta 1 (muscle) like [Source:ZFIN;Acc:ZDB-GENE-060811-1]) HSP 1 Score: 111.309 bits (277), Expect = 3.147e-26 Identity = 84/325 (25.85%), Postives = 167/325 (51.38%), Query Frame = 1
Query: 70 INSSRGAGFHDYSSFGDEEKLITQL--MKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMV--------PVQHGSTVDNSYLPNSNISEWIILYVKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAVV 1011
+N AG + EE L+ L ++++ VRP TG V V + + Q+++ + ++S +L+W+D RL+W P+ N+ + L +++WLPD+ + N N+ +FDF + V + G V W+ I SC + V YFPFD Q C ++ + +I + ++H +D S P S EW I + T + + YQ I+ + ++R+PL++II ++VP +++ A F L D+G+++ + +S++L++T+++++++ P + +PV+ YL+ + +++ +L V+
Sbjct: 10 LNKCCSAGVRGLEA---EENLLKDLFVVQQYKTLVRPAR--TATGRVTVRLGMTLSQLISLPACQPDMTLSRLISLSWEDPRLSWDPRNYDNLRSIRLSPKRVWLPDIALSNN-NDGNFDFGLYVH--VLVDYTGAVRWVPPSIYRSSCGMQVKYFPFDWQNCSMVFQSFTYDTSEINLEYALDEHRQEIRH-IIIDESTFPVSG--EWQIKHKPSRKNT--NPRDPLYQDITFYLIMERKPLFYIINIVVPCILITICAVFTFYLPPDAGEKMGLCISVLLALTVFLLLLADKVPETSLGVPVIVNYLMFTMVIVTACVILTVI 321
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Sea Lamprey
Match: htr3a (5-hydroxytryptamine (serotonin) receptor 3A [Source:ZFIN;Acc:ZDB-GENE-071012-5]) HSP 1 Score: 90.8929 bits (224), Expect = 1.351e-19 Identity = 64/304 (21.05%), Postives = 140/304 (46.05%), Query Frame = 1
Query: 130 LITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGV---MNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYVKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTLDDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAVVNQKLREK 1032
L ++L + VRP ++ +IV I + IL + + + W+ W D L W P + I Q+ +P+ +W+PD+ + ++ + D + + +S++G V + + +C LD+ FPFD Q C + T W I + + + N EW ++ V + N + + I + ++R+PL++++ +++P + L + + DSG+R++ ++L+L ++++++V P + P++ +Y + + LL +S + + +L K
Sbjct: 38 LSSRLSSGYDKGVRPVKNWR--QPIIVAIDVMLYAILNVDEKNQVLTAYIWYRQRWTDEFLQWDPVQYDGIEQISIPTNNIWVPDIMISEFVDVGKSPDIGY-------VYLSYNGTVMNYKPLQVVSACSLDIYSFPFDVQNCTLTFTSWLHTSNDINLTLWRTTEEIKEDKSIFLNFGEWELISVPNELLHPLYGEN-RFSELKIYVVIRRRPLFYVVNLIMPSAFLMVMDAGFYLPPDSGERVSFKITLLLGYSVFLIVVQDTLPATPIGTPLIAVYFVVCMALLVISLMETIFIVRLVHK 331
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Nematostella
Match: EDO47631 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RLM5]) HSP 1 Score: 120.939 bits (302), Expect = 2.452e-30 Identity = 86/309 (27.83%), Postives = 157/309 (50.81%), Query Frame = 1
Query: 121 EEKLITQLM--KRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYVKFNYKTYVSQINITYQY--ISISIRVQRQPLYFIILVLVPFSMLSGLACLIF-TLDDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVL-----CIYLLNQLGLLSVSTVLAVVNQ 1017
E+ LI L+ R+S + RP A+++ + I+A + F+ + + W+D L W+P G +TQ+ L + +W P V + N + ++ + R V DG V WM ++ SC +DV YFPFD Q C II W V ++ + P+ G Y+ N SEW +L +T VS I + I+ S+ ++R+ LY+ + ++P ++++ L L+F T D++G+R+ V ++++LS+ ++ +++ + P S + LP+L CI + L ++S VL ++
Sbjct: 4 EDHLIRHLLNTTRYSPRFRPVR--DVKEALVLRHGMMLKTIVAVEEKNMVFTTNVRLRMGWKDAFLQWNPADYGGVTQINLEASDIWTPPVIIYNQAGDLGESITSSNTPRPVVRSDGTVLWMVPTVIKSSCVIDVKYFPFDQQLCKIIFGSWHYDVSKLDLQPLD-GKVDTTRYITN---SEWKLLSAT-AVRTQVSHICCRQEVARITYSLHIERRRLYYSMNFILPCTIIAFLMLLVFMTPDNTGERMAVGVTILLSLAVFFLMLETIMPIS-QMLPLLGKYYCCIIIEGAAALGAMSGVLRYIHH 304
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Nematostella
Match: EDO44896 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RUG1]) HSP 1 Score: 124.405 bits (311), Expect = 3.035e-30 Identity = 75/310 (24.19%), Postives = 158/310 (50.97%), Query Frame = 1
Query: 85 GAGFHDYSSFGDEEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNI---SEW-IILYVKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTV 999
G+ H+++ GD L+K ++ P T +V ++Q++ + + + W W + L W P + G IT+V + + K+W+PD+ + N +++ + ++R+ ++HDG W +C +DV++FPFD QTC++ W V V D S L +S +EW +I K Y + + ++++ +R+PL+++ ++VP +++G+ L F L +SG+R+T++++++L+M +++ + + N PR+ N+PVL I+ + + +++S +
Sbjct: 7 GSDLHEHTLLGD-------LLKGYNKDAHPVPILNKT-QYMVTFGLELVQLVNVDDKNQIITTNVWVRQRWTNLLLKWDPDKYGGITRVRIDASKIWIPDIVLYNSADSEFSGGLEKYKTRVILNHDGVNAWYSPASFRSTCQIDVTFFPFDQQTCFMKFGSWTFEV-------VDLDIFADKSPLHSSQYMKSAEWDLIAASKKRNVEYYACCTYPFSDVTVTWVFRRKPLFYVFNLIVPCLIITGMVLLGFMLPPESGERITLSITVLLAMAVFLQLAAENLPRNSDNVPVLGIFYITVMVEVALSLI 301
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Nematostella
Match: EDO49732 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RFJ2]) HSP 1 Score: 118.627 bits (296), Expect = 7.241e-30 Identity = 70/282 (24.82%), Postives = 144/282 (51.06%), Query Frame = 1
Query: 118 DEEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHG--STVDNSYLPNSNISEWIILYVKFN-YKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTLD-DSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVL 951
DEE+L L + + + T + + V + +++ + ++ E++ W W + L W+P+ GNIT++ +P+ +W+PD+ + N S +++ ++ +G+ TW I + C LDV YFPFD QTC ++ W + ++ +V + +S L N EW +++ K Y+ I ++IS+R+QR+ Y+++ +++P ++++ L F L +SG+R+ + ++++LSM ++ + S P S + P+L
Sbjct: 3 DEERLFRFLFQGYKERRLVTPLRNRSEPITVVFSAHLLGLAKVNEKEQSIKTHLWIKEEWYNPFLMWNPEEFGNITEIIVPANMIWVPDIILYNKG-------STLFNTKVIIAFNGNNTWRSPAIYNTMCVLDVKYFPFDEQTCDLVFASWTRDISKLNLVTTSDTVPRSRRDSKLFQEN-EEWRVMFAKMKRYEVIFDWSEIPVADVTISVRLQRRTYYYVMNLILPCTLIACTIFLEFILPAESGERVGLGITILLSMAVFQELTSEKLPSSSEHFPLL 276
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Nematostella
Match: EDO49045 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RHV9]) HSP 1 Score: 119.398 bits (298), Expect = 1.401e-29 Identity = 78/289 (26.99%), Postives = 148/289 (51.21%), Query Frame = 1
Query: 106 SSFGDEEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQ-SRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYVKFNYKTYVSQI--NITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTLD-DSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIY 960
+S DE++L+ +L+ VRP V ++IT+N I+ + + S S W +W L+W P G + Q+ + S+ LW PD V+ ++FD + +R+ V G V W + C +DV+ FPFDSQ C I WQ ++ ++ + +TV ++ + N EW + V + Q N Y IS I +QR+ L++++ +++P +++ LA F + + G+R++ ++++LSMT+++++V+ + P + +PV+ +Y
Sbjct: 7 ASATDEQRLLERLINASGSGVRPILDLARPTNVTLDITFN--SIIDVDEKHQILSSSVWIRQSWIAETLSWDPAEYGGVNQIVVSSQLLWQPDT-VLYNNIFEEFDSRLDTTVTRVRVYSSGFVYWAMPYVFKTMCKIDVTDFPFDSQRCPITFGAWQYDQNEVNLINNKRLATVASTRVEN---GEWTVEKVAIERRVIFYQCCPNQPYPEISFVIHMQRRSLFYVVNLVLPNFLITLLAFFSFFIPVECGERMSFVITVLLSMTVFLLLVAESIPPTSEAVPVIGVY 289
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Nematostella
Match: EDO42054 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S2J7]) HSP 1 Score: 120.168 bits (300), Expect = 5.576e-29 Identity = 74/297 (24.92%), Postives = 156/297 (52.53%), Query Frame = 1
Query: 121 EEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPN-SNISEWIILYV--KFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTV 999
E++L+ L + + +VRP F + V V + ++IQI+A + + ++S W W + L W+ + G I V L K+W+PD+ + N + + ++ + S DG W +C ++V YFPFDSQ C + W ++ M ST D++ L N EW +L + K N + + + + +++ + +QR+PLY++ +++P ++++ L + F L +SG+++ + ++++L+MT+++++V+ P + ++P+L Y + + + ++S V
Sbjct: 38 EKRLLADLFRNYDSEVRPV--FNDSDKVNVEFSLSLIQIIAVNSKSQLVTVSVWIRQKWTNPMLAWNTSKYGGIESVNLNPAKVWIPDIILYNNADETYAGGLEKYKTSVIASSDGTQEWNSPASFTSTCNINVRYFPFDSQNCSLKFGSWTYVGNRLTMT-----STSDSADLSKYVNNGEWHLLAMPAKLN-RVFYNCCKYPFYDVTLYLEIQRKPLYYVFNLIIPCALIATLTLIKFFLPPESGEKVGLGITVLLAMTVFLLLVAETLPSTSDHIPLLGQYFVATMFVTAISLV 326
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Medaka
Match: ENSORLT00000017941.2 (neuronal acetylcholine receptor subunit alpha-3-like [Source:NCBI gene;Acc:101168601]) HSP 1 Score: 137.502 bits (345), Expect = 2.240e-34 Identity = 84/305 (27.54%), Postives = 159/305 (52.13%), Query Frame = 1
Query: 100 DYSSFGDEEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEW-IILYVKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAV 1008
D S E++L +L +R++ +RP + V V ++ Q++ + + + W W DY+L W+P I + +PS K+W PD+ + N N DF + +++ + DG +TW+ I SCP+D++YFPFD Q C + W +I +V + GS V+ S EW II + + + Y I+ S ++R PL++ I +++P ++S L L+F L D G+++T+ +S++LS+T+++++++ P + +P++ YLL + +++S V+ V
Sbjct: 22 DCFSSKAEDRLFRKLFRRYNQFIRPVE--NVSDPVTVEFEVSISQLVKVDEVNQIMETNLWLRHIWNDYKLRWTPAEFDGIEFIRVPSNKIWRPDIVLYN---NAVGDFLVEDKTKALLKFDGTITWVPPAIFKSSCPMDITYFPFDYQNCSMKFGSWTYDKAKIDLVLI--GSKVNLKDFWESG--EWEIIDAPGYKHDIKYNCCEEIYPDITYSFYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITV 317
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Medaka
Match: chrna3 (neuronal acetylcholine receptor subunit alpha-3 [Source:NCBI gene;Acc:101159658]) HSP 1 Score: 136.346 bits (342), Expect = 1.309e-33 Identity = 81/298 (27.18%), Postives = 157/298 (52.68%), Query Frame = 1
Query: 121 EEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYV-KFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAV 1008
E KL + + ++ +RP + VIV ++ Q++ + + + W W DY+L W+PK G + + +PS ++W PD+ + NN DF +++ + +G VTW+ I SC +DV+YFPFD Q C + W +I +V + GST++ S EW I+ + + + Y I+ S+ ++R PL++ I +++P ++S L L+F L D G+++T+ +S++LS+T+++++++ P + +P++ YLL + +++S V+ V
Sbjct: 28 EHKLFSVIFSNYNQYIRPVE--NVSDPVIVQFEVSMSQLVKVDEVNQIMETNLWLRHIWNDYKLKWNPKEFGGVEFIRVPSNRIWKPDIVLY---NNAVGDFQVDDKTKALLRFNGDVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWTYDKAKIDLVLI--GSTINLKDFWESG--EWTIIDAPGYKHDIKYNCCEEIYTDITYSLYIRRLPLFYTINMIIPCLLISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITV 316
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Medaka
Match: chrnb2 (cholinergic receptor nicotinic beta 2 subunit [Source:NCBI gene;Acc:101175346]) HSP 1 Score: 133.265 bits (334), Expect = 5.417e-33 Identity = 89/316 (28.16%), Postives = 175/316 (55.38%), Query Frame = 1
Query: 82 RGAGFHDYSSFGD-EEKLITQLM--KRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYV---KFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAV 1008
RG+ +H S D EE+L+ L+ ++ +RP + V V + ++ Q+++ + E+ + + W T WQDYRL W P+ + +V LPS+ +WLPDV + NN D + S VS+DG + W+ I +C ++V +FPFD Q C + W +I +V +++D+ + P+ EW I+ + + + ++ITY +I ++R+PL++ I +++P +++ LA L+F L D G+++T+ +S++L++T++++++S P + ++P++ YL+ + L++ S V +V
Sbjct: 27 RGSFYHFCSLGADTEERLVEHLLNPAHYNKLIRPAT--NGSELVTVQLMVSLAQLISVHEREQVMTTNVWLTQEWQDYRLTWVPEEFDGMLKVRLPSKHIWLPDVVLY---NNADGVYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTLRFRSWTYDRTEIDLVLRADVASMDD-FTPS---GEWDIIALPGRRNENPADPAYVDITYDFI-----IRRKPLFYTINLIIPCVLITSLAILVFYLPSDCGEKMTLCISVLLALTVFLLLISKIVPPTSLDVPLVGKYLMFTMVLVTFSIVTSV 328
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Medaka
Match: chrnd (cholinergic receptor nicotinic delta subunit [Source:NCBI gene;Acc:101164515]) HSP 1 Score: 132.494 bits (332), Expect = 1.735e-32 Identity = 87/323 (26.93%), Postives = 172/323 (53.25%), Query Frame = 1
Query: 40 FEIVAILSIFINSSRGAGFHDYSSFGDEEKLITQLM--KRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYL-------PNS--NISEWIILY--VKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTLD-DSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLL 966
F+ ++S F+ + A + S +EE+LI L K+++ ++RP Q V V + + +++ +A+ET + W TW DYRL+W+ I + LPS +WLP++ + NN D F S + V G W+ I SC ++V+YFPFD Q C + T + K+I M+ ++ + +N + P S EW I++ K N ++ + +Q I+ + ++R+PL++I+ +++P ++S LA ++ L DSG+++T+++S++L+ +++++++S P + ++P++ YL+
Sbjct: 3 FQQAGLISAFLLTLLSA---ECSGRNEEERLINYLFLEKKYNKELRPVE--QHGDTVDVYLALTLSNLISLKEADETLLTNVWIDHTWIDYRLSWNVSEFDGIDMLRLPSNMVWLPEIVL---ENNNDAQFEVAYYSNVLVDPSGLCYWLPPAIFRSSCSINVNYFPFDWQNCTLKFTSLTYNAKEIRML-LKEDADEENKWTVEWIIIDPESFTENGEWEIIHRPAKRNTYKHIPMESNKHQDITFYLVIKRKPLFYIVNIIIPCVLISFLATFVYYLPADSGEKMTLSISVLLAQSVFLLLISQRLPETSMSVPLIVKYLM 316
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Medaka
Match: chrnb1l (acetylcholine receptor subunit beta [Source:NCBI gene;Acc:101157009]) HSP 1 Score: 130.183 bits (326), Expect = 8.861e-32 Identity = 90/353 (25.50%), Postives = 183/353 (51.84%), Query Frame = 1
Query: 16 IMLNVFGKFEIVAILSIFINSSRGAGFHDYSSFGDEEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQ----------HGSTVD-NSYLPNSNISEWIILY--VKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAVVNQKLREK 1032
IM + KF + +F+ S F S E L +L + ++LKVRP ++ V+V + + Q+++ ++ + + + + W DYRL+W P+ NI + +P+ K+W PD+ ++ NN D F + V DG + W+ I +C +DV+YFPFD Q C ++ ++S+ V +Q H +D N++ N EW I + + N K + Y+ I+ + ++R+PL++II +++P + S LA +F L +G+++T+++S+++++T+++++++ P + + P++ Y++ + L++ S +L+VV L +
Sbjct: 4 IMGQMKMKFSVRTSFIVFVCISFCLAFTGASE--TERNLHQKLFQNYNLKVRPARYWE--EKVMVRVGMTLSQLVSLNEKNGEMTTNVYMNMQWSDYRLSWKPEEYDNIDVLRIPANKVWRPDIYLI---NNNDGHFDVALYVNVLVYSDGTINWLPPAIYRSACSIDVAYFPFDWQNCSMV---FRSYTYDASEVDLQYFLDDDGKEIHEIVIDENAFTEN---GEWAICHKPTRKNVK------DGLYEDITFYLIIERKPLFYIINIILPCILTSVLAIFVFYLPPGAGEKMTLSISVLIALTVFMLLLADKVPETSLSTPIIVNYVMFTMILVTFSVILSVVVLNLHHR 337
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Planmine SMEST
Match: SMESG000061997.1 (SMESG000061997.1) HSP 1 Score: 1073.54 bits (2775), Expect = 0.000e+0 Identity = 513/513 (100.00%), Postives = 513/513 (100.00%), Query Frame = 1
Query: 16 IMLNVFGKFEIVAILSIFINSSRGAGFHDYSSFGDEEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYVKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTLDDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAVVNQKLREKYRLSFWQDYQQARTIFNGYYLEESPLMTDYCSDSPLATLKRAWQSQRYKNTKTETIFNSNAEDNLKSTQAYNSHRFKNIVKENDNPKSQPIKTNKDDRKHPPKSSFDDEGNKKRPFFNELFDSDQNHKGNIRQQRYYKKLANKLDRWELAIYLFISLINAIICLVLMPHYATEE 1554
IMLNVFGKFEIVAILSIFINSSRGAGFHDYSSFGDEEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYVKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTLDDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAVVNQKLREKYRLSFWQDYQQARTIFNGYYLEESPLMTDYCSDSPLATLKRAWQSQRYKNTKTETIFNSNAEDNLKSTQAYNSHRFKNIVKENDNPKSQPIKTNKDDRKHPPKSSFDDEGNKKRPFFNELFDSDQNHKGNIRQQRYYKKLANKLDRWELAIYLFISLINAIICLVLMPHYATEE
Sbjct: 261 IMLNVFGKFEIVAILSIFINSSRGAGFHDYSSFGDEEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYVKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTLDDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAVVNQKLREKYRLSFWQDYQQARTIFNGYYLEESPLMTDYCSDSPLATLKRAWQSQRYKNTKTETIFNSNAEDNLKSTQAYNSHRFKNIVKENDNPKSQPIKTNKDDRKHPPKSSFDDEGNKKRPFFNELFDSDQNHKGNIRQQRYYKKLANKLDRWELAIYLFISLINAIICLVLMPHYATEE 773
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Planmine SMEST
Match: SMESG000061997.1 (SMESG000061997.1) HSP 1 Score: 1064.29 bits (2751), Expect = 0.000e+0 Identity = 512/512 (100.00%), Postives = 512/512 (100.00%), Query Frame = 1
Query: 19 MLNVFGKFEIVAILSIFINSSRGAGFHDYSSFGDEEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYVKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTLDDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAVVNQKLREKYRLSFWQDYQQARTIFNGYYLEESPLMTDYCSDSPLATLKRAWQSQRYKNTKTETIFNSNAEDNLKSTQAYNSHRFKNIVKENDNPKSQPIKTNKDDRKHPPKSSFDDEGNKKRPFFNELFDSDQNHKGNIRQQRYYKKLANKLDRWELAIYLFISLINAIICLVLMPHYATEE 1554
MLNVFGKFEIVAILSIFINSSRGAGFHDYSSFGDEEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYVKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTLDDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAVVNQKLREKYRLSFWQDYQQARTIFNGYYLEESPLMTDYCSDSPLATLKRAWQSQRYKNTKTETIFNSNAEDNLKSTQAYNSHRFKNIVKENDNPKSQPIKTNKDDRKHPPKSSFDDEGNKKRPFFNELFDSDQNHKGNIRQQRYYKKLANKLDRWELAIYLFISLINAIICLVLMPHYATEE
Sbjct: 1 MLNVFGKFEIVAILSIFINSSRGAGFHDYSSFGDEEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYVKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTLDDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAVVNQKLREKYRLSFWQDYQQARTIFNGYYLEESPLMTDYCSDSPLATLKRAWQSQRYKNTKTETIFNSNAEDNLKSTQAYNSHRFKNIVKENDNPKSQPIKTNKDDRKHPPKSSFDDEGNKKRPFFNELFDSDQNHKGNIRQQRYYKKLANKLDRWELAIYLFISLINAIICLVLMPHYATEE 512
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Planmine SMEST
Match: SMESG000077071.1 (SMESG000077071.1) HSP 1 Score: 447.203 bits (1149), Expect = 6.454e-153 Identity = 228/343 (66.47%), Postives = 268/343 (78.13%), Query Frame = 1
Query: 142 LMKR-HSLKVRPTAC-FQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYVKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTLDDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAVVNQKLREKYRLSFWQDYQQARTIFNGYYLEESPL---MTDYCSDSPLATLKR 1155
LMK + L VRP AC C VIVNITYNVIQILAFSQAEET ISGWFT+ W D+RL W+PK G+I V L S+ LW PDVGVMNG+ ++DFDFS QSR+SV H G++ W+HG ILDV+CPLDV YFPFD QTCY+ILTPWQS +KQ+++ PVQHGS VDNSYLPNSN+SEW I+ VKF+ KTY SQI+ YQ+ISISI ++RQPLYFI+LVLVPFSMLSGLACLIFTL D+GDRLTVALSLVLSMTMYVVIVS+NAPRSMR LPVL +YLLNQLGLLSV+T+LAVVN KLR+ R S T N Y P+ D C++SP+ +L++
Sbjct: 2 LMKSSNELTVRPNACRVHCNNPVIVNITYNVIQILAFSQAEETLKISGWFTVEWMDFRLRWNPKYYGDIDTVSLNSKNLWRPDVGVMNGKASEDFDFSNIPQSRISVKHTGNIYWLHGAILDVTCPLDVRYFPFDKQTCYLILTPWQSSIKQMVIEPVQHGSAVDNSYLPNSNVSEWEIVDVKFSKKTYESQISEVYQFISISISLKRQPLYFIVLVLVPFSMLSGLACLIFTLSDTGDRLTVALSLVLSMTMYVVIVSTNAPRSMRTLPVLGVYLLNQLGLLSVATILAVVNNKLRDNNRYS-----DMISTNPNEIY--RGPMNYRCYDQCNESPIKSLRK 337
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Planmine SMEST
Match: SMESG000077071.1 (SMESG000077071.1) HSP 1 Score: 446.432 bits (1147), Expect = 1.130e-152 Identity = 225/338 (66.57%), Postives = 265/338 (78.40%), Query Frame = 1
Query: 154 HSLKVRPTAC-FQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYVKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTLDDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAVVNQKLREKYRLSFWQDYQQARTIFNGYYLEESPL---MTDYCSDSPLATLKR 1155
+ L VRP AC C VIVNITYNVIQILAFSQAEET ISGWFT+ W D+RL W+PK G+I V L S+ LW PDVGVMNG+ ++DFDFS QSR+SV H G++ W+HG ILDV+CPLDV YFPFD QTCY+ILTPWQS +KQ+++ PVQHGS VDNSYLPNSN+SEW I+ VKF+ KTY SQI+ YQ+ISISI ++RQPLYFI+LVLVPFSMLSGLACLIFTL D+GDRLTVALSLVLSMTMYVVIVS+NAPRSMR LPVL +YLLNQLGLLSV+T+LAVVN KLR+ R S T N Y P+ D C++SP+ +L++
Sbjct: 5 NELTVRPNACRVHCNNPVIVNITYNVIQILAFSQAEETLKISGWFTVEWMDFRLRWNPKYYGDIDTVSLNSKNLWRPDVGVMNGKASEDFDFSNIPQSRISVKHTGNIYWLHGAILDVTCPLDVRYFPFDKQTCYLILTPWQSSIKQMVIEPVQHGSAVDNSYLPNSNVSEWEIVDVKFSKKTYESQISEVYQFISISISLKRQPLYFIVLVLVPFSMLSGLACLIFTLSDTGDRLTVALSLVLSMTMYVVIVSTNAPRSMRTLPVLGVYLLNQLGLLSVATILAVVNNKLRDNNRYS-----DMISTNPNEIY--RGPMNYRCYDQCNESPIKSLRK 335
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Planmine SMEST
Match: SMESG000043840.1 (SMESG000043840.1) HSP 1 Score: 433.335 bits (1113), Expect = 1.330e-146 Identity = 245/475 (51.58%), Postives = 315/475 (66.32%), Query Frame = 1
Query: 121 EEKLITQLMKRHSLKVRPTAC-FQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYVKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTLDDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAVVNQKLREKYRLSFWQDYQQARTIFNGYYLEESPLMTDYCSDSPLATLKRAWQSQRYKNTKTETIFNSNAEDNLKSTQAYNSHRFKNIVKENDNPKSQPIKTNKDDRKHPPKSSFDDEGNKKRPFFNELFDSDQNHKGNIRQQRYYKKLANKLDRWELAIYLFISLINAIICLVLMPHY 1542
EE+L+ L KR+ LKVRP C C V VNITYNVIQILAFSQAEET SISGWFT+ W D RL W+ ++ GN+ V +P++ +WLPD+G+MN +N+K+FDFS +QSR+SV DG +TW+HG ILDV+CPLDV +FPFD QTCY+++TPWQS KQ+L+ P Q GS VDNSYLPNSN+SEW I V F K Y S +N+TYQYI +SI ++RQPLYF++LVL+PFSMLSGLACLIFTL+D+GDRL+VALSLVLSMTMYVVIVSSNAPRSMR+LPV+ IYLL+QLGLLS++TVLAV+N K+R +++S ++R GY E Y +DSP+ L+ + N K FN A+ N + A NS R V + + N + F P + R YK LA++ D+ E+ YL IS IN + CL+++P Y
Sbjct: 26 EEELLNILRKRN-LKVRPNPCRSHCANPVNVNITYNVIQILAFSQAEETMSISGWFTIVWSDNRLEWNSEKYGNLNAVSIPAQDMWLPDIGIMNVKNSKNFDFSTIAQSRISVESDGRITWLHGAILDVTCPLDVRFFPFDVQTCYLVITPWQSSDKQMLIHPYQLGSAVDNSYLPNSNVSEWEIRAVHFKRKRYRSDLNVTYQYIRVSIHLRRQPLYFVVLVLIPFSMLSGLACLIFTLEDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRSLPVIGIYLLDQLGLLSLATVLAVINNKVR-YFKVS---PESKSRKQPTGYRCPE------YNNDSPIIQLQNSKNRMNDANHKINKKFN--ADYNFSKSYANNSVRVNFNV-------ANSLSRNSSPSTSLSSTDF-------LPLYQP------------RGVNIYKDLADRFDKIEMVTYLIISFINGVFCLIVVPSY 461 The following BLAST results are available for this feature:
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30019169 ID=SMED30019169|Name=Neuronal acetylcholine receptor subunit alpha-6|organism=Schmidtea mediterranea sexual|type=transcript|length=1893bpback to top protein sequence of SMED30019169-orf-1 >SMED30019169-orf-1 ID=SMED30019169-orf-1|Name=SMED30019169-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=513bp MLNVFGKFEIVAILSIFINSSRGAGFHDYSSFGDEEKLITQLMKRHSLKVback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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