Neuronal acetylcholine receptor subunit alpha-6

Overview
NameNeuronal acetylcholine receptor subunit alpha-6
Smed IDSMED30019169
Length (bp)1893
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Neuronal acetylcholine receptor subunit alpha-6 (SMED30019169) t-SNE clustered cells

Violin plots show distribution of expression levels for Neuronal acetylcholine receptor subunit alpha-6 (SMED30019169) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Neuronal acetylcholine receptor subunit alpha-6 (SMED30019169) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Neuronal acetylcholine receptor subunit alpha-6 (SMED30019169) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30019169

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 10

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
head regionSMED30019169h1SMcG0018566 SmedASXL_011036SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
pharynxSMED30019169h1SMcG0003338 dd_Smed_v4_2273_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30019169h1SMcG0003338 dd_Smed_v4_2273_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30019169h1SMcG0003338 dd_Smed_v4_2273_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30019169h1SMcG0018566 dd_Smed_v4_27539_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30019169h1SMcG0018566 dd_Smed_v4_27539_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30019169h1SMcG0018566 dd_Smed_v4_27539_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30019169h1SMcG0018566 dd_Smed_v6_27539_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
pharynxSMED30019169h1SMcG0003338 dd_Smed_v6_2273_0dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30019169h1SMcG0003338 dd_Smed_v4_2273_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Human
Match: CHRNA3 (cholinergic receptor nicotinic alpha 3 subunit [Source:HGNC Symbol;Acc:HGNC:1957])

HSP 1 Score: 135.961 bits (341), Expect = 1.418e-33
Identity = 76/298 (25.50%), Postives = 156/298 (52.35%), Query Frame = 1 
Query:  121 EEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYVK-FNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAV 1008
            E +L  +L + ++  +RP A    +  VI++   ++ Q++   +  +    + W    W DY+L W+P   G    + +P++K+W PD+ + N   N   DF    +++  + + G VTW+   I   SC +DV+YFPFD Q C +    W     +I +V +     + + +       EW I+    + +    +     Y  I+ S+ ++R PL++ I +++P  ++S L  L+F L  D G+++T+ +S++LS+T+++++++   P +   +P++  YLL  +  +++S V+ V
Sbjct:   35 EHRLFERLFEDYNEIIRPVA--NVSDPVIIHFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYN---NAVGDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYW----ESGEWAIIKAPGYKHDIKYNCCEEIYPDITYSLYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITV 323
[Close]
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Human
Match: CHRNA6 (cholinergic receptor nicotinic alpha 6 subunit [Source:HGNC Symbol;Acc:HGNC:15963])

HSP 1 Score: 135.961 bits (341), Expect = 1.776e-33
Identity = 80/299 (26.76%), Postives = 156/299 (52.17%), Query Frame = 1 
Query:  121 EEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVD-NSYLPNSNISEW-IILYVKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAV 1008
            EE+L  +L   ++  +RP      +  V V+    + Q+    +  +    + W    W DY+L W P     I  + +P++K+W PD+ + N   N   DF  + +++  + ++G +TW    I   SCP+D+++FPFD Q C +    W     +I ++ +  GS VD N +  N   SEW II    + +    +     Y  I+ S  ++R P+++ I +++P   +S L  L+F L  D G+++T+ +S++LS+T+++++++   P +   +P++  YLL  +  +++S V+ V
Sbjct:   34 EERLFHKLFSHYNQFIRPVE--NVSDPVTVHFEVAITQLANVDEVNQIMETNLWLRHIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYN---NAVGDFQVEGKTKALLKYNGMITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLII--GSKVDMNDFWEN---SEWEIIDASGYKHDIKYNCCEEIYTDITYSFYIRRLPMFYTINLIIPCLFISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVVPLVGEYLLFTMIFVTLSIVVTV 322
[Close]
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Human
Match: CHRND (cholinergic receptor nicotinic delta subunit [Source:HGNC Symbol;Acc:HGNC:1965])

HSP 1 Score: 135.961 bits (341), Expect = 2.475e-33
Identity = 88/316 (27.85%), Postives = 164/316 (51.90%), Query Frame = 1 
Query:  109 SFGDEEKLITQLM--KRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNI----------SEWIILY--VKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTLD-DSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAVV 1011
               +EE+LI  L   K ++ ++RP A      +V V +   +  +++  + EET + + W    W D RL W+ +  GNI+ + LP + +WLP++ +    NN D  F       + V H G V W+   I   SCP+ V+YFPFD Q C +  +  +   K+I +   Q     +N   P   I           EW I++   + N        + + Q I+  + ++R+PL++II +LVP  ++S +  L+F L  DSG++ +VA+S++L+ +++++++S   P +   +P++  +LL  + L+++  V+ V+
Sbjct:   21 GLNEEERLIRHLFQEKGYNKELRPVA--HKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGNISVLRLPPDMVWLPEIVL---ENNNDGSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISVTYFPFDWQNCSLKFSSLKYTAKEITLSLKQDAK--ENRTYPVEWIIIDPEGFTENGEWEIVHRPARVNVDPRAPLDSPSRQDITFYLIIRRKPLFYIINILVPCVLISFMVNLVFYLPADSGEKTSVAISVLLAQSVFLLLISKRLPATSMAIPLIGKFLLFGMVLVTMVVVICVI 329
[Close]
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Human
Match: CHRNA3 (cholinergic receptor nicotinic alpha 3 subunit [Source:HGNC Symbol;Acc:HGNC:1957])

HSP 1 Score: 135.191 bits (339), Expect = 3.900e-33
Identity = 76/298 (25.50%), Postives = 156/298 (52.35%), Query Frame = 1 
Query:  121 EEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYVK-FNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAV 1008
            E +L  +L + ++  +RP A    +  VI++   ++ Q++   +  +    + W    W DY+L W+P   G    + +P++K+W PD+ + N   N   DF    +++  + + G VTW+   I   SC +DV+YFPFD Q C +    W     +I +V +     + + +       EW I+    + +    +     Y  I+ S+ ++R PL++ I +++P  ++S L  L+F L  D G+++T+ +S++LS+T+++++++   P +   +P++  YLL  +  +++S V+ V
Sbjct:   35 EHRLFERLFEDYNEIIRPVA--NVSDPVIIHFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYN---NAVGDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYW----ESGEWAIIKAPGYKHDIKYNCCEEIYPDITYSLYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITV 323
[Close]
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Human
Match: CHRNA3 (cholinergic receptor nicotinic alpha 3 subunit [Source:HGNC Symbol;Acc:HGNC:1957])

HSP 1 Score: 135.191 bits (339), Expect = 3.900e-33
Identity = 76/298 (25.50%), Postives = 156/298 (52.35%), Query Frame = 1 
Query:  121 EEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYVK-FNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAV 1008
            E +L  +L + ++  +RP A    +  VI++   ++ Q++   +  +    + W    W DY+L W+P   G    + +P++K+W PD+ + N   N   DF    +++  + + G VTW+   I   SC +DV+YFPFD Q C +    W     +I +V +     + + +       EW I+    + +    +     Y  I+ S+ ++R PL++ I +++P  ++S L  L+F L  D G+++T+ +S++LS+T+++++++   P +   +P++  YLL  +  +++S V+ V
Sbjct:   35 EHRLFERLFEDYNEIIRPVA--NVSDPVIIHFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYN---NAVGDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYW----ESGEWAIIKAPGYKHDIKYNCCEEIYPDITYSLYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITV 323
[Close]
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Celegans
Match: acr-21 (pep chromosome:WBcel235:III:6581927:6586549:1 gene:WBGene00000060.1 transcript:F27B3.2b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:acr-21)

HSP 1 Score: 135.961 bits (341), Expect = 1.851e-33
Identity = 82/323 (25.39%), Postives = 173/323 (53.56%), Query Frame = 1 
Query:   58 LSIFINSSRGAGFHDYSSFGDEE--KLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSR-MSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQI-LMVPVQHGSTVDNSYLPNSNISEWIILYVKFNYKTYV-SQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAV 1008
            +S+F+  +   G ++ SS  D+   +L   L+  ++ +VRP+        + V   +++ QI+   +  +  + + W  L W DY+L W P+   N+T++ +PS+K+W PD+ +    NN D  +     S  + V + G++ W    I   SCPLDV ++PFD QTC +    W     +I L++  + G   +  Y+ N   +EW ++ ++      + S     Y +I + + ++R+ ++++  +++P  ++S +A + F +  DSG+++T+ ++ +LS T+++++V+   P +   LP++ IY    + L+++ T + V
Sbjct:    8 ISLFLFFNGAHGGNELSSRADQNVMRLYRDLLYDYNNEVRPSV--HSKEPINVTFVFSLTQIIDVDERNQILTTNSWIRLHWVDYKLVWDPRLYQNVTRIHIPSDKIWKPDIILY---NNADAQYMKSVMSTDVIVDYLGNIHWPLSAIFTSSCPLDVKHYPFDRQTCILKYASWAYDGTKIDLLLKSEQGDLTN--YITN---TEWSLIGIRAEKNQVIYSCCPEPYPFIDVHVTIERRAMFYVFNLILPCVLISLIALMGFYMPTDSGEKVTLGITSLLSTTVFLMMVAEGMPPTAEALPLIGIYFGVTIMLVALGTAMTV 320
[Close]
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Celegans
Match: acr-21 (pep chromosome:WBcel235:III:6581927:6586549:1 gene:WBGene00000060.1 transcript:F27B3.2a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:acr-21)

HSP 1 Score: 135.576 bits (340), Expect = 2.930e-33
Identity = 82/323 (25.39%), Postives = 173/323 (53.56%), Query Frame = 1 
Query:   58 LSIFINSSRGAGFHDYSSFGDEE--KLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSR-MSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQI-LMVPVQHGSTVDNSYLPNSNISEWIILYVKFNYKTYV-SQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAV 1008
            +S+F+  +   G ++ SS  D+   +L   L+  ++ +VRP+        + V   +++ QI+   +  +  + + W  L W DY+L W P+   N+T++ +PS+K+W PD+ +    NN D  +     S  + V + G++ W    I   SCPLDV ++PFD QTC +    W     +I L++  + G   +  Y+ N   +EW ++ ++      + S     Y +I + + ++R+ ++++  +++P  ++S +A + F +  DSG+++T+ ++ +LS T+++++V+   P +   LP++ IY    + L+++ T + V
Sbjct:    8 ISLFLFFNGAHGGNELSSRADQNVMRLYRDLLYDYNNEVRPSV--HSKEPINVTFVFSLTQIIDVDERNQILTTNSWIRLHWVDYKLVWDPRLYQNVTRIHIPSDKIWKPDIILY---NNADAQYMKSVMSTDVIVDYLGNIHWPLSAIFTSSCPLDVKHYPFDRQTCILKYASWAYDGTKIDLLLKSEQGDLTN--YITN---TEWSLIGIRAEKNQVIYSCCPEPYPFIDVHVTIERRAMFYVFNLILPCVLISLIALMGFYMPTDSGEKVTLGITSLLSTTVFLMMVAEGMPPTAEALPLIGIYFGVTIMLVALGTAMTV 320
[Close]
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Celegans
Match: acr-15 (AcetylCholine Receptor [Source:UniProtKB/TrEMBL;Acc:O16926])

HSP 1 Score: 130.183 bits (326), Expect = 4.168e-32
Identity = 98/383 (25.59%), Postives = 182/383 (47.52%), Query Frame = 1 
Query:  121 EEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYVKFNYKTYVSQINIT----------YQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTLD-DSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYL--LNQLGLLSVSTVLAVVNQKLREKY---RLSFWQDYQQARTIFNGYYLEESPL-----MTDYCSDSPLATLKRAWQSQRYKNTKTETIFN 1206
            E +LI  LM  +  + RPT     +  V+V++   + QI+  S+ EE   ++ W    W+D  L W P    N+T +  P + LW PD+ +    N+ D +F +  +  +   H G++ WM   I  VSC LD+ +FPFD Q CY     W     +I +   + G    + ++PN    EWII+    +Y+T     NIT          Y+ I+ ++ ++R+ LY+   ++ P  +   L  L FT+  ++ +++ + +S+ L++ +++ I+S   P++   +P+L ++    N + +L+ S  + V +   R ++   R+ FW  +           LE SP      M D   ++   TL  +W+ +  + +   T F 
Sbjct:   22 EVRLINDLMSGYVREERPT--LDSSKPVVVSLGVFLQQIINLSEKEEQLEVNAWLKFQWRDENLRWEPTAYENVTDLRHPPDALWTPDILLY---NSVDSEFDSSYKVNLVNYHTGNINWMPPGIFKVSCKLDIYWFPFDEQVCYFKFGSWTYTRDKIQL---EKGDFDFSEFIPN---GEWIII----DYRT-----NITVKQYECCPEQYEDITFTLHLRRRTLYYSFNLIAPVLLTMILVILGFTVSPETCEKVGLQISVSLAICIFLTIMSELTPQTSEAVPLLGVFFHTCNFISVLATSFTVYVQSFHFRNQHVHERMDFWMRF---------ILLEWSPWLLRMKMPD--RENNFQTLTESWKGRNRRESMARTAFE 373
[Close]
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Celegans
Match: acr-21 (pep chromosome:WBcel235:III:6583461:6586549:1 gene:WBGene00000060.1 transcript:F27B3.2d.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:acr-21)

HSP 1 Score: 131.339 bits (329), Expect = 4.914e-32
Identity = 76/298 (25.50%), Postives = 160/298 (53.69%), Query Frame = 1 
Query:  127 KLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSR-MSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQI-LMVPVQHGSTVDNSYLPNSNISEWIILYVKFNYKTYV-SQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAV 1008
            +L   L+  ++ +VRP+        + V   +++ QI+   +  +  + + W  L W DY+L W P+   N+T++ +PS+K+W PD+ +    NN D  +     S  + V + G++ W    I   SCPLDV ++PFD QTC +    W     +I L++  + G   +  Y+ N   +EW ++ ++      + S     Y +I + + ++R+ ++++  +++P  ++S +A + F +  DSG+++T+ ++ +LS T+++++V+   P +   LP++ IY    + L+++ T + V
Sbjct:    2 RLYRDLLYDYNNEVRPSV--HSKEPINVTFVFSLTQIIDVDERNQILTTNSWIRLHWVDYKLVWDPRLYQNVTRIHIPSDKIWKPDIILY---NNADAQYMKSVMSTDVIVDYLGNIHWPLSAIFTSSCPLDVKHYPFDRQTCILKYASWAYDGTKIDLLLKSEQGDLTN--YITN---TEWSLIGIRAEKNQVIYSCCPEPYPFIDVHVTIERRAMFYVFNLILPCVLISLIALMGFYMPTDSGEKVTLGITSLLSTTVFLMMVAEGMPPTAEALPLIGIYFGVTIMLVALGTAMTV 289
[Close]
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Celegans
Match: unc-29 (Acetylcholine receptor subunit beta-type unc-29 [Source:UniProtKB/Swiss-Prot;Acc:P48181])

HSP 1 Score: 130.183 bits (326), Expect = 5.218e-32
Identity = 73/284 (25.70%), Postives = 153/284 (53.87%), Query Frame = 1 
Query:  118 DEEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYVKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLL 966
            DEE+L+  + + ++  ++P         +IV +   ++ ++   + ++    + W TL W D+++ W+P   G I Q+ +  +K+WLPD+ +    NN D ++       + ++H G + W+   I   SC +DV +FPFD Q C ++   W  +  +I +  VQ    VD S    S+I  W ++ V  +     S+I          +R++R+ L++ +++++P  +++ L+  +F L  DSG+++T+ +S++LS+ +++++VS   P +   +P++  YLL
Sbjct:   29 DEERLMVDVFRGYNSLIQPVRN-SSELPLIVKMALQLVLLINVDEKDQVMHTNVWLTLQWHDFQMKWNPVNYGEIKQIRVSPDKVWLPDIVLF---NNADGNYEVSFMCNVVINHKGDMLWVPPAIYKSSCIIDVEFFPFDEQVCTLVFGSWTYNENEIKLEFVQ-AELVDVSEYSASSI--WDVIDVPASLVNKRSRIE-------FQVRIRRKTLFYTVVLIIPTVLMAFLSMAVFFLPTDSGEKITLTISVLLSIVVFLLLVSKILPPTSSTIPLMAKYLL 298
[Close]
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Fly
Match: nAChRalpha2 (gene:FBgn0000039 transcript:FBtr0084639)

HSP 1 Score: 147.902 bits (372), Expect = 1.779e-37
Identity = 86/309 (27.83%), Postives = 161/309 (52.10%), Query Frame = 1 
Query:  118 DEEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDN---------SYLPNSNISEWIILYVKFN-YKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTLD-DSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAVV 1011
            D ++L   L+  ++  +RP +    T  V+V +   + Q++  +  ++  + + W    WQD++  W P   G +T++++PSE +WLPD+ +    NN D ++   + ++  + + G V W    I   SC +DV YFPFD QTC++    W     QI +  +   +  DN          Y P+    EW IL V    ++ Y       Y  I  +I ++R+ L++ + +++P   +S L+ L+F L  DSG+++ + +S++LS TM+ +++S   P +   LP+L  YLL  + L+ +S V+ ++
Sbjct:   44 DAKRLYDDLLSNYNRLIRPVS--NNTDTVLVKLGLRLSQLIDLNLKDQILTTNVWLEHEWQDHKFKWDPSEYGGVTELYVPSEHIWLPDIVLY---NNADGEYVVTTMTKAILHYTGKVVWTPPAIFKSSCEIDVRYFPFDQQTCFMKFGSWTYDGDQIDLKHISQKNDKDNKVEIGIDLREYYPS---VEWDILGVPAERHEKYYPCCAEPYPDIFFNITLRRKTLFYTVNLIIPCVGISYLSVLVFYLPADSGEKIALCISILLSQTMFFLLISEIIPSTSLALPLLGKYLLFTMLLVGLSVVITII 344
[Close]
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Fly
Match: nAChRalpha2 (gene:FBgn0000039 transcript:FBtr0084640)

HSP 1 Score: 147.902 bits (372), Expect = 1.779e-37
Identity = 86/309 (27.83%), Postives = 161/309 (52.10%), Query Frame = 1 
Query:  118 DEEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDN---------SYLPNSNISEWIILYVKFN-YKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTLD-DSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAVV 1011
            D ++L   L+  ++  +RP +    T  V+V +   + Q++  +  ++  + + W    WQD++  W P   G +T++++PSE +WLPD+ +    NN D ++   + ++  + + G V W    I   SC +DV YFPFD QTC++    W     QI +  +   +  DN          Y P+    EW IL V    ++ Y       Y  I  +I ++R+ L++ + +++P   +S L+ L+F L  DSG+++ + +S++LS TM+ +++S   P +   LP+L  YLL  + L+ +S V+ ++
Sbjct:   44 DAKRLYDDLLSNYNRLIRPVS--NNTDTVLVKLGLRLSQLIDLNLKDQILTTNVWLEHEWQDHKFKWDPSEYGGVTELYVPSEHIWLPDIVLY---NNADGEYVVTTMTKAILHYTGKVVWTPPAIFKSSCEIDVRYFPFDQQTCFMKFGSWTYDGDQIDLKHISQKNDKDNKVEIGIDLREYYPS---VEWDILGVPAERHEKYYPCCAEPYPDIFFNITLRRKTLFYTVNLIIPCVGISYLSVLVFYLPADSGEKIALCISILLSQTMFFLLISEIIPSTSLALPLLGKYLLFTMLLVGLSVVITII 344
[Close]
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Fly
Match: nAChRalpha1 (gene:FBgn0000036 transcript:FBtr0330310)

HSP 1 Score: 129.028 bits (323), Expect = 4.697e-31
Identity = 84/322 (26.09%), Postives = 166/322 (51.55%), Query Frame = 1 
Query:  118 DEEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSY----LPNSNIS-EWIILYV-KFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTV--LAVVNQKLRE--KYRLSFW 1050
            D ++L   L+  ++  +RP      +  + V +   + Q++  +   +  + + W    W DY+L W+P   G +  + +PSE +WLPD+ + N   N D ++     ++  + H G V W    I    C +DV YFPFD QTC++    W      + +  ++  +  DN      L +  IS EW I+ V     + + S     Y  I  ++ ++R+ L++ + +++P   +S L+ L+F L  DSG+++++ +S++LS+T++ ++++   P +   +P+L  YLL  + L+++S V  +AV+N   R    +R++ W
Sbjct:   24 DAKRLYDDLLSNYNRLIRPVG--NNSDRLTVKMGLRLSQLIDVNLKNQIMTTNVWVEQEWNDYKLKWNPDDYGGVDTLHVPSEHIWLPDIVLYN---NADGNYEVTIMTKAILHHTGKVVWKPPAIYKSFCEIDVEYFPFDEQTCFMKFGSWTYDGYMVDLRHLKQTADSDNIEVGIDLQDYYISVEWDIMRVPAVRNEKFYSCCEEPYLDIVFNLTLRRKTLFYTVNLIIPCVGISFLSVLVFYLPSDSGEKISLCISILLSLTVFFLLLAEIIPPTSLTVPLLGKYLLFTMMLVTLSVVVTIAVLNVNFRSPVTHRMAPW 340
[Close]
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Fly
Match: nAChRalpha1 (gene:FBgn0000036 transcript:FBtr0334916)

HSP 1 Score: 128.642 bits (322), Expect = 5.314e-31
Identity = 84/322 (26.09%), Postives = 166/322 (51.55%), Query Frame = 1 
Query:  118 DEEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSY----LPNSNIS-EWIILYV-KFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTV--LAVVNQKLRE--KYRLSFW 1050
            D ++L   L+  ++  +RP      +  + V +   + Q++  +   +  + + W    W DY+L W+P   G +  + +PSE +WLPD+ +    NN D ++     ++  + H G V W    I    C +DV YFPFD QTC++    W      + +  ++  +  DN      L +  IS EW I+ V     + + S     Y  I  ++ ++R+ L++ + +++P   +S L+ L+F L  DSG+++++ +S++LS+T++ ++++   P +   +P+L  YLL  + L+++S V  +AV+N   R    +R++ W
Sbjct:   24 DAKRLYDDLLSNYNRLIRPVG--NNSDRLTVKMGLRLSQLIDVNLKNQIMTTNVWVEQEWNDYKLKWNPDDYGGVDTLHVPSEHIWLPDIVL---YNNADGNYEVTIMTKAILHHTGKVVWKPPAIYKSFCEIDVEYFPFDEQTCFMKFGSWTYDGYMVDLRHLKQTADSDNIEVGIDLQDYYISVEWDIMRVPAVRNEKFYSCCEEPYLDIVFNLTLRRKTLFYTVNLIIPCVGISFLSVLVFYLPSDSGEKISLCISILLSLTVFFLLLAEIIPPTSLTVPLLGKYLLFTMMLVTLSVVVTIAVLNVNFRSPVTHRMAPW 340
[Close]
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Fly
Match: nAChRalpha1 (gene:FBgn0000036 transcript:FBtr0084619)

HSP 1 Score: 128.642 bits (322), Expect = 5.314e-31
Identity = 84/322 (26.09%), Postives = 166/322 (51.55%), Query Frame = 1 
Query:  118 DEEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSY----LPNSNIS-EWIILYV-KFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTV--LAVVNQKLRE--KYRLSFW 1050
            D ++L   L+  ++  +RP      +  + V +   + Q++  +   +  + + W    W DY+L W+P   G +  + +PSE +WLPD+ +    NN D ++     ++  + H G V W    I    C +DV YFPFD QTC++    W      + +  ++  +  DN      L +  IS EW I+ V     + + S     Y  I  ++ ++R+ L++ + +++P   +S L+ L+F L  DSG+++++ +S++LS+T++ ++++   P +   +P+L  YLL  + L+++S V  +AV+N   R    +R++ W
Sbjct:   24 DAKRLYDDLLSNYNRLIRPVG--NNSDRLTVKMGLRLSQLIDVNLKNQIMTTNVWVEQEWNDYKLKWNPDDYGGVDTLHVPSEHIWLPDIVL---YNNADGNYEVTIMTKAILHHTGKVVWKPPAIYKSFCEIDVEYFPFDEQTCFMKFGSWTYDGYMVDLRHLKQTADSDNIEVGIDLQDYYISVEWDIMRVPAVRNEKFYSCCEEPYLDIVFNLTLRRKTLFYTVNLIIPCVGISFLSVLVFYLPSDSGEKISLCISILLSLTVFFLLLAEIIPPTSLTVPLLGKYLLFTMMLVTLSVVVTIAVLNVNFRSPVTHRMAPW 340
[Close]
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Zebrafish
Match: chrne (cholinergic receptor, nicotinic, epsilon [Source:ZFIN;Acc:ZDB-GENE-040808-32])

HSP 1 Score: 137.502 bits (345), Expect = 4.046e-34
Identity = 86/320 (26.88%), Postives = 170/320 (53.12%), Query Frame = 1 
Query:  115 GDEE-KLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIIL--TPWQSHVKQILMVPVQHGSTVD------NSYLPNSNISEWIILY---VKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL--DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGL--LSVSTVLAVVNQKLR 1026
            G+EE +LI    K +S  +RP         V V +   +  +++ ++ EET + + W  + W DYRL W+     +I Q+ +P   +WLPD+ +    NN D  F     + + +S DG + W+   I   +C ++++YFPFD Q C ++     + ++   I++   ++G  ++       ++  N    EW I +    K   + Y S  ++ YQ +  +I +QR+PL+++I +++P S++S L  L + L     G +LTV++S++L+ T++++++S   P +  ++P++  YL+  + +  L V+  + V+N  LR
Sbjct:   26 GNEESQLIADKFKNYSKNIRPAR--HADEKVKVQVKLTLTNLISLNEKEETLTTNVWIEIQWHDYRLAWNTSEYHDIEQIRVPYYTVWLPDIVL---ENNIDGKFDVAYYANVLISSDGSMYWLPPAIYRSTCAIEITYFPFDWQNCTLVFRSQTYSANEIDIVLAEDENGKPIEWVDIDPEAFTEN---GEWAIKHRPARKLTNQRY-SPDDLEYQEVYYNIIIQRKPLFYVINIILPCSLISSLVVLAYFLPAKAGGQKLTVSISVLLAQTVFLILISQKIPETSLSVPLIGKYLIFVMSMTTLIVTNCIIVLNYSLR 336
[Close]
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Zebrafish
Match: chrne (cholinergic receptor, nicotinic, epsilon [Source:ZFIN;Acc:ZDB-GENE-040808-32])

HSP 1 Score: 137.502 bits (345), Expect = 4.046e-34
Identity = 86/320 (26.88%), Postives = 170/320 (53.12%), Query Frame = 1 
Query:  115 GDEE-KLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIIL--TPWQSHVKQILMVPVQHGSTVD------NSYLPNSNISEWIILY---VKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL--DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGL--LSVSTVLAVVNQKLR 1026
            G+EE +LI    K +S  +RP         V V +   +  +++ ++ EET + + W  + W DYRL W+     +I Q+ +P   +WLPD+ +    NN D  F     + + +S DG + W+   I   +C ++++YFPFD Q C ++     + ++   I++   ++G  ++       ++  N    EW I +    K   + Y S  ++ YQ +  +I +QR+PL+++I +++P S++S L  L + L     G +LTV++S++L+ T++++++S   P +  ++P++  YL+  + +  L V+  + V+N  LR
Sbjct:   26 GNEESQLIADKFKNYSKNIRPAR--HADEKVKVQVKLTLTNLISLNEKEETLTTNVWIEIQWHDYRLAWNTSEYHDIEQIRVPYYTVWLPDIVL---ENNIDGKFDVAYYANVLISSDGSMYWLPPAIYRSTCAIEITYFPFDWQNCTLVFRSQTYSANEIDIVLAEDENGKPIEWVDIDPEAFTEN---GEWAIKHRPARKLTNQRY-SPDDLEYQEVYYNIIIQRKPLFYVINIILPCSLISSLVVLAYFLPAKAGGQKLTVSISVLLAQTVFLILISQKIPETSLSVPLIGKYLIFVMSMTTLIVTNCIIVLNYSLR 336
[Close]
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Zebrafish
Match: chrnb1l (cholinergic receptor, nicotinic, beta 1 (muscle) like [Source:ZFIN;Acc:ZDB-GENE-060811-1])

HSP 1 Score: 136.346 bits (342), Expect = 6.107e-34
Identity = 90/333 (27.03%), Postives = 176/333 (52.85%), Query Frame = 1 
Query:   70 INSSRGAGFHDYSSFGDEEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNI--------SEWIILYVKFNYKTYVSQINI---TYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAVVNQKLREK 1032
            IN SR A          E +L+  L + ++LKVRP   +     V+V +   ++Q+++ +Q     + + +  + W DYRL+W+P+    I  V +P  K+W PD+ ++   NN D  F       + V  DG V+W+   I   SC ++V+YFPFD Q C ++   ++S+      V +Q+G   D + L    I         EW I +         S+ NI    Y+ I+  + ++R+PL+++I ++VP  + S LA  +F L   +G+++T+++S+++++T+++++++   P +   +P++  Y++  + L++ S +L+VV   L  +
Sbjct:   10 INGSRKAS-------EAERRLLEDLFQDYNLKVRPARTWN--ERVMVRVGMTLVQLISLNQKNGEMTTNVFMNMEWTDYRLSWNPEDYDKIDVVRIPPVKVWRPDIYLI---NNNDGQFDVALYVNVLVRSDGTVSWLPPAIYRSSCSIEVAYFPFDWQNCSMV---FRSYTYDSSEVDLQYGLDEDGNELHEIVIDENAFTENGEWQICHKP-------SRKNIQDDLYEDITFYLIIERKPLFYVINIIVPCILTSVLAIFVFYLPPGAGEKMTLSISVLIALTVFMLLLADKVPETSLAIPIIVNYVMFTMILVTFSVILSVVVLNLHHR 320
[Close]
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Zebrafish
Match: chrnb1l (cholinergic receptor, nicotinic, beta 1 (muscle) like [Source:ZFIN;Acc:ZDB-GENE-060811-1])

HSP 1 Score: 135.961 bits (341), Expect = 8.043e-34
Identity = 89/330 (26.97%), Postives = 176/330 (53.33%), Query Frame = 1 
Query:   70 INSSRGAGFHDYSSFGDEEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNI--------SEWIILYVKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAVVNQKLREK 1032
            IN SR A          E +L+  L + ++LKVRP   +     V+V +   ++Q+++ +Q     + + +  + W DYRL+W+P+    I  V +P  K+W PD+ ++   NN D  F       + V  DG V+W+   I   SC ++V+YFPFD Q C ++   ++S+      V +Q+G   D + L    I         EW I + K + K     +   Y+ I+  + ++R+PL+++I ++VP  + S LA  +F L   +G+++T+++S+++++T+++++++   P +   +P++  Y++  + L++ S +L+VV   L  +
Sbjct:   10 INGSRKAS-------EAERRLLEDLFQDYNLKVRPARTWN--ERVMVRVGMTLVQLISLNQKNGEMTTNVFMNMEWTDYRLSWNPEDYDKIDVVRIPPVKVWRPDIYLI---NNNDGQFDVALYVNVLVRSDGTVSWLPPAIYRSSCSIEVAYFPFDWQNCSMV---FRSYTYDSSEVDLQYGLDEDGNELHEIVIDENAFTENGEWQICH-KPSRKNVQDDL---YEDITFYLIIERKPLFYVINIIVPCILTSVLAIFVFYLPPGAGEKMTLSISVLIALTVFMLLLADKVPETSLAIPIIVNYVMFTMILVTFSVILSVVVLNLHHR 320
[Close]
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Zebrafish
Match: chrnb1l (cholinergic receptor, nicotinic, beta 1 (muscle) like [Source:ZFIN;Acc:ZDB-GENE-060811-1])

HSP 1 Score: 135.191 bits (339), Expect = 1.387e-33
Identity = 85/316 (26.90%), Postives = 171/316 (54.11%), Query Frame = 1 
Query:  121 EEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNI--------SEWIILYVKFNYKTYVSQINI---TYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAVVNQKLREK 1032
            E +L+  L + ++LKVRP   +     V+V +   ++Q+++ +Q     + + +  + W DYRL+W+P+    I  V +P  K+W PD+ ++   NN D  F       + V  DG V+W+   I   SC ++V+YFPFD Q C ++   ++S+      V +Q+G   D + L    I         EW I +         S+ NI    Y+ I+  + ++R+PL+++I ++VP  + S LA  +F L   +G+++T+++S+++++T+++++++   P +   +P++  Y++  + L++ S +L+VV   L  +
Sbjct:    6 ERRLLEDLFQDYNLKVRPARTWN--ERVMVRVGMTLVQLISLNQKNGEMTTNVFMNMEWTDYRLSWNPEDYDKIDVVRIPPVKVWRPDIYLI---NNNDGQFDVALYVNVLVRSDGTVSWLPPAIYRSSCSIEVAYFPFDWQNCSMV---FRSYTYDSSEVDLQYGLDEDGNELHEIVIDENAFTENGEWQICHKP-------SRKNIQDDLYEDITFYLIIERKPLFYVINIIVPCILTSVLAIFVFYLPPGAGEKMTLSISVLIALTVFMLLLADKVPETSLAIPIIVNYVMFTMILVTFSVILSVVVLNLHHR 306
[Close]
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Xenopus
Match: ncaph (non-SMC condensin I complex subunit H [Source:Xenbase;Acc:XB-GENE-5738397])

HSP 1 Score: 147.517 bits (371), Expect = 8.986e-38
Identity = 85/299 (28.43%), Postives = 160/299 (53.51%), Query Frame = 1 
Query:  121 EEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVD-NSYLPNSNISEW-IILYVKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAV 1008
            EEKL  +L+ R++  +RP      +  V+V+    + Q++   +  +    + W    W DY+L W+PK    I  + +P++K+W PD+ + N   N   DF  + +S+  V ++G +TW    I   SCP+D+++FPFD Q C +    W     +I +  +  GS VD   +  N   SEW I+    F +    +     Y  I+ S  ++R P+++ I +++P   LS L  L+F L  D G+++T+ +S++LS+T+++++++   P +   +P++  YLL  +  +++S V+ V
Sbjct:   27 EEKLFQKLLARYNQHIRPVE--NVSDPVMVHFEVAITQLVNVDEVNQILETNLWLRHIWNDYKLQWNPKEYDGIEFMRIPADKIWKPDIVLYN---NAVGDFQVEGKSKALVKYNGLITWSPPAIFKSSCPMDITFFPFDHQNCSMKFGSWSYDKAKIDLAII--GSKVDMKDFWEN---SEWEIVDASGFKHDIKYNCCEEIYTDITYSFYIRRLPMFYTINLIMPCLFLSFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLVGEYLLFTMIFVTLSIVVTV 315
[Close]
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Xenopus
Match: ncaph (non-SMC condensin I complex subunit H [Source:Xenbase;Acc:XB-GENE-5738397])

HSP 1 Score: 146.747 bits (369), Expect = 1.296e-37
Identity = 85/299 (28.43%), Postives = 160/299 (53.51%), Query Frame = 1 
Query:  121 EEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVD-NSYLPNSNISEW-IILYVKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAV 1008
            EEKL  +L+ R++  +RP      +  V+V+    + Q++   +  +    + W    W DY+L W+PK    I  + +P++K+W PD+ + N   N   DF  + +S+  V ++G +TW    I   SCP+D+++FPFD Q C +    W     +I +  +  GS VD   +  N   SEW I+    F +    +     Y  I+ S  ++R P+++ I +++P   LS L  L+F L  D G+++T+ +S++LS+T+++++++   P +   +P++  YLL  +  +++S V+ V
Sbjct:   16 EEKLFQKLLARYNQHIRPVE--NVSDPVMVHFEVAITQLVNVDEVNQILETNLWLRHIWNDYKLQWNPKEYDGIEFMRIPADKIWKPDIVLYN---NAVGDFQVEGKSKALVKYNGLITWSPPAIFKSSCPMDITFFPFDHQNCSMKFGSWSYDKAKIDLAII--GSKVDMKDFWEN---SEWEIVDASGFKHDIKYNCCEEIYTDITYSFYIRRLPMFYTINLIMPCLFLSFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLVGEYLLFTMIFVTLSIVVTV 304
[Close]
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Xenopus
Match: ncaph (non-SMC condensin I complex subunit H [Source:Xenbase;Acc:XB-GENE-5738397])

HSP 1 Score: 147.132 bits (370), Expect = 1.359e-37
Identity = 85/299 (28.43%), Postives = 160/299 (53.51%), Query Frame = 1 
Query:  121 EEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVD-NSYLPNSNISEW-IILYVKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAV 1008
            EEKL  +L+ R++  +RP      +  V+V+    + Q++   +  +    + W    W DY+L W+PK    I  + +P++K+W PD+ + N   N   DF  + +S+  V ++G +TW    I   SCP+D+++FPFD Q C +    W     +I +  +  GS VD   +  N   SEW I+    F +    +     Y  I+ S  ++R P+++ I +++P   LS L  L+F L  D G+++T+ +S++LS+T+++++++   P +   +P++  YLL  +  +++S V+ V
Sbjct:   34 EEKLFQKLLARYNQHIRPVE--NVSDPVMVHFEVAITQLVNVDEVNQILETNLWLRHIWNDYKLQWNPKEYDGIEFMRIPADKIWKPDIVLYN---NAVGDFQVEGKSKALVKYNGLITWSPPAIFKSSCPMDITFFPFDHQNCSMKFGSWSYDKAKIDLAII--GSKVDMKDFWEN---SEWEIVDASGFKHDIKYNCCEEIYTDITYSFYIRRLPMFYTINLIMPCLFLSFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLVGEYLLFTMIFVTLSIVVTV 322
[Close]
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Xenopus
Match: ncaph (non-SMC condensin I complex subunit H [Source:Xenbase;Acc:XB-GENE-5738397])

HSP 1 Score: 146.362 bits (368), Expect = 2.272e-37
Identity = 85/299 (28.43%), Postives = 160/299 (53.51%), Query Frame = 1 
Query:  121 EEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVD-NSYLPNSNISEW-IILYVKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAV 1008
            EEKL  +L+ R++  +RP      +  V+V+    + Q++   +  +    + W    W DY+L W+PK    I  + +P++K+W PD+ + N   N   DF  + +S+  V ++G +TW    I   SCP+D+++FPFD Q C +    W     +I +  +  GS VD   +  N   SEW I+    F +    +     Y  I+ S  ++R P+++ I +++P   LS L  L+F L  D G+++T+ +S++LS+T+++++++   P +   +P++  YLL  +  +++S V+ V
Sbjct:   22 EEKLFQKLLARYNQHIRPVE--NVSDPVMVHFEVAITQLVNVDEVNQILETNLWLRHIWNDYKLQWNPKEYDGIEFMRIPADKIWKPDIVLYN---NAVGDFQVEGKSKALVKYNGLITWSPPAIFKSSCPMDITFFPFDHQNCSMKFGSWSYDKAKIDLAII--GSKVDMKDFWEN---SEWEIVDASGFKHDIKYNCCEEIYTDITYSFYIRRLPMFYTINLIMPCLFLSFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLVGEYLLFTMIFVTLSIVVTV 310
[Close]
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Xenopus
Match: ncaph (non-SMC condensin I complex subunit H [Source:Xenbase;Acc:XB-GENE-5738397])

HSP 1 Score: 146.362 bits (368), Expect = 2.310e-37
Identity = 85/299 (28.43%), Postives = 160/299 (53.51%), Query Frame = 1 
Query:  121 EEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVD-NSYLPNSNISEW-IILYVKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAV 1008
            EEKL  +L+ R++  +RP      +  V+V+    + Q++   +  +    + W    W DY+L W+PK    I  + +P++K+W PD+ + N   N   DF  + +S+  V ++G +TW    I   SCP+D+++FPFD Q C +    W     +I +  +  GS VD   +  N   SEW I+    F +    +     Y  I+ S  ++R P+++ I +++P   LS L  L+F L  D G+++T+ +S++LS+T+++++++   P +   +P++  YLL  +  +++S V+ V
Sbjct:   21 EEKLFQKLLARYNQHIRPVE--NVSDPVMVHFEVAITQLVNVDEVNQILETNLWLRHIWNDYKLQWNPKEYDGIEFMRIPADKIWKPDIVLYN---NAVGDFQVEGKSKALVKYNGLITWSPPAIFKSSCPMDITFFPFDHQNCSMKFGSWSYDKAKIDLAII--GSKVDMKDFWEN---SEWEIVDASGFKHDIKYNCCEEIYTDITYSFYIRRLPMFYTINLIMPCLFLSFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLVGEYLLFTMIFVTLSIVVTV 309
[Close]
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Mouse
Match: Chrna3 (cholinergic receptor, nicotinic, alpha polypeptide 3 [Source:MGI Symbol;Acc:MGI:87887])

HSP 1 Score: 138.658 bits (348), Expect = 8.527e-35
Identity = 78/298 (26.17%), Postives = 156/298 (52.35%), Query Frame = 1 
Query:  121 EEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYVK-FNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAV 1008
            E +L   L + ++  +RP A    +  VI+    ++ Q++   +  +    + W    W DY+L W P     +  + +P+EK+W PD+ + N   N D DF    +++  + + G VTW+   I   SC +DV+YFPFD Q C +    W     +I +V +     + + +       EW I+    + ++   +     YQ I+ S+ ++R PL++ I +++P  ++S L  L+F L  D G+++T+ +S++LS+T+++++++   P +   +P++  YLL  +  +++S V+ V
Sbjct:   29 EHRLFQYLFEDYNEIIRPVA--NVSHPVIIQFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWKPSDYQGVEFMRVPAEKIWKPDIVLYN---NADGDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYW----ESGEWAIIKAPGYKHEIKYNCCEEIYQDITYSLYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITV 317
[Close]
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Mouse
Match: Chrna6 (cholinergic receptor, nicotinic, alpha polypeptide 6 [Source:MGI Symbol;Acc:MGI:106213])

HSP 1 Score: 139.043 bits (349), Expect = 1.042e-34
Identity = 82/310 (26.45%), Postives = 159/310 (51.29%), Query Frame = 1 
Query:   88 AGFHDYSSFGDEEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVD-NSYLPNSNISEW-IILYVKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAV 1008
            A F   +    EE+L  +L   ++  +RP      +  V V+    + Q+    +  +    + W    W+DYRL W P     I  + +P++ +W PD+ + N   N   DF  + +++  + +DG +TW    I   SCP+D+++FPFD Q C +    W     +I ++ +  GS VD N +  N   SEW I+    + +    +     Y  I+ S  ++R P+++ I +++P   +S L  L+F L  D G+++T+ +S++LS+T+++++++   P +   +P++  YLL  +  +++S V+ V
Sbjct:   23 ALFKGSTGCESEEQLFHRLFAHYNRFIRPVE--NVSDPVTVHFELAITQLANVDEVNQIMETNLWLRHIWKDYRLRWDPTEYDGIETLRVPADNIWKPDIVLYN---NAVGDFQVEGKTKALLKYDGVITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLII--GSKVDMNDFWEN---SEWEIVDASGYKHDIKYNCCEEIYTDITYSFYIRRLPMFYTINLIIPCLFISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLVGEYLLFTMIFVTLSIVVTV 322
[Close]
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Mouse
Match: Chrna3 (cholinergic receptor, nicotinic, alpha polypeptide 3 [Source:MGI Symbol;Acc:MGI:87887])

HSP 1 Score: 138.658 bits (348), Expect = 1.345e-34
Identity = 78/298 (26.17%), Postives = 156/298 (52.35%), Query Frame = 1 
Query:  121 EEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYVK-FNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAV 1008
            E +L   L + ++  +RP A    +  VI+    ++ Q++   +  +    + W    W DY+L W P     +  + +P+EK+W PD+ + N   N D DF    +++  + + G VTW+   I   SC +DV+YFPFD Q C +    W     +I +V +     + + +       EW I+    + ++   +     YQ I+ S+ ++R PL++ I +++P  ++S L  L+F L  D G+++T+ +S++LS+T+++++++   P +   +P++  YLL  +  +++S V+ V
Sbjct:   29 EHRLFQYLFEDYNEIIRPVA--NVSHPVIIQFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWKPSDYQGVEFMRVPAEKIWKPDIVLYN---NADGDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYW----ESGEWAIIKAPGYKHEIKYNCCEEIYQDITYSLYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITV 317
[Close]
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Mouse
Match: Chrna3 (cholinergic receptor, nicotinic, alpha polypeptide 3 [Source:MGI Symbol;Acc:MGI:87887])

HSP 1 Score: 138.658 bits (348), Expect = 1.379e-34
Identity = 78/298 (26.17%), Postives = 156/298 (52.35%), Query Frame = 1 
Query:  121 EEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYVK-FNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAV 1008
            E +L   L + ++  +RP A    +  VI+    ++ Q++   +  +    + W    W DY+L W P     +  + +P+EK+W PD+ + N   N D DF    +++  + + G VTW+   I   SC +DV+YFPFD Q C +    W     +I +V +     + + +       EW I+    + ++   +     YQ I+ S+ ++R PL++ I +++P  ++S L  L+F L  D G+++T+ +S++LS+T+++++++   P +   +P++  YLL  +  +++S V+ V
Sbjct:   34 EHRLFQYLFEDYNEIIRPVA--NVSHPVIIQFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWKPSDYQGVEFMRVPAEKIWKPDIVLYN---NADGDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYW----ESGEWAIIKAPGYKHEIKYNCCEEIYQDITYSLYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITV 322
[Close]
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Mouse
Match: Chrnd (cholinergic receptor, nicotinic, delta polypeptide [Source:MGI Symbol;Acc:MGI:87893])

HSP 1 Score: 135.576 bits (340), Expect = 2.102e-33
Identity = 88/316 (27.85%), Postives = 162/316 (51.27%), Query Frame = 1 
Query:  109 SFGDEEKLITQLM--KRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNI----------SEWIILY--VKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAVV 1011
               +E++LI  L   K +   +RP A  +    V V ++  +  +++  + EET + + W    W D RL W     GNIT + LP + +WLP++ +    NN D  F       + V   G+VTW+   I   SCP+ V+YFPFD Q C +  +  +   K+I +   Q     +N   P   I           EW I++   K N    V   +  +Q ++  + ++R+PL++II +LVP  ++S +  L+F L  D G++ +VA+S++L+ +++++++S   P +   +P++  +LL  + L+++  V+ V+
Sbjct:   24 GLNEEQRLIQHLFNEKGYDKDLRPVA--RKEDKVDVALSLTLSNLISLKEVEETLTTNVWIDHAWVDSRLQWDANDFGNITVLRLPPDMVWLPEIVL---ENNNDGSFQISYACNVLVYDSGYVTWLPPAIFRSSCPISVTYFPFDWQNCSLKFSSLKYTAKEITLSLKQEEE--NNRSYPIEWIIIDPEGFTENGEWEIVHRAAKLNVDPSVPMDSTNHQDVTFYLIIRRKPLFYIINILVPCVLISFMINLVFYLPGDCGEKTSVAISVLLAQSVFLLLISKRLPATSMAIPLVGKFLLFGMVLVTMVVVICVI 332
[Close]
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. UniProt/SwissProt
Match: sp|P17644|ACH2_DROME (Acetylcholine receptor subunit alpha-like 2 OS=Drosophila melanogaster OX=7227 GN=nAChRalpha2 PE=2 SV=1)

HSP 1 Score: 147.902 bits (372), Expect = 1.783e-36
Identity = 86/309 (27.83%), Postives = 161/309 (52.10%), Query Frame = 1 
Query:  118 DEEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDN---------SYLPNSNISEWIILYVKFN-YKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTLD-DSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAVV 1011
            D ++L   L+  ++  +RP +    T  V+V +   + Q++  +  ++  + + W    WQD++  W P   G +T++++PSE +WLPD+ +    NN D ++   + ++  + + G V W    I   SC +DV YFPFD QTC++    W     QI +  +   +  DN          Y P+    EW IL V    ++ Y       Y  I  +I ++R+ L++ + +++P   +S L+ L+F L  DSG+++ + +S++LS TM+ +++S   P +   LP+L  YLL  + L+ +S V+ ++
Sbjct:   44 DAKRLYDDLLSNYNRLIRPVS--NNTDTVLVKLGLRLSQLIDLNLKDQILTTNVWLEHEWQDHKFKWDPSEYGGVTELYVPSEHIWLPDIVLY---NNADGEYVVTTMTKAILHYTGKVVWTPPAIFKSSCEIDVRYFPFDQQTCFMKFGSWTYDGDQIDLKHISQKNDKDNKVEIGIDLREYYPS---VEWDILGVPAERHEKYYPCCAEPYPDIFFNITLRRKTLFYTVNLIIPCVGISYLSVLVFYLPADSGEKIALCISILLSQTMFFLLISEIIPSTSLALPLLGKYLLFTMLLVGLSVVITII 344
[Close]
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. UniProt/SwissProt
Match: sp|P25110|ACHD_RAT (Acetylcholine receptor subunit delta OS=Rattus norvegicus OX=10116 GN=Chrnd PE=1 SV=1)

HSP 1 Score: 145.206 bits (365), Expect = 7.802e-36
Identity = 92/316 (29.11%), Postives = 167/316 (52.85%), Query Frame = 1 
Query:  109 SFGDEEKLITQLM--KRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNI----------SEWIILY--VKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAVV 1011
               +E++LI  L   K ++ ++RP A  +    V V ++  +  +++  + EET + + W    W D RL W+    GNIT + LPS+ +WLP++ +    NN D  F       + VS  GHVTW+   I   SCP+ V+YFPFD Q C +  +  +   K+I +   Q     DN   P   I           EW I++   K N    V   +  +Q ++  + ++R+PL++II +LVP  ++S +  L+F L  D G++ +VA+S++L+ +++++++S   P +   +P++  +LL  + L+++  V+ V+
Sbjct:   21 GLNEEQRLIQHLFEEKGYNKELRPVA--RKEDIVDVALSLTLSNLISLKEVEETLTTNVWIDHAWIDSRLQWNANEFGNITVLRLPSDMVWLPEIVL---ENNNDGSFQISYACNVLVSDSGHVTWLPPAIFRSSCPISVTYFPFDWQNCSLKFSSLKYTAKEIRLSLKQEEE--DNRSYPIEWIIIDPEGFTENGEWEIVHRAAKVNVDPSVPMDSTNHQDVTFYLIIRRKPLFYIINILVPCVLISFMINLVFYLPGDCGEKTSVAISVLLAQSVFLLLISKRLPATSMAIPLVGKFLLFGMVLVTMVVVICVI 329
[Close]
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. UniProt/SwissProt
Match: sp|P23414|ACH1_SCHGR (Acetylcholine receptor subunit alpha-L1 OS=Schistocerca gregaria OX=7010 PE=2 SV=1)

HSP 1 Score: 145.206 bits (365), Expect = 1.104e-35
Identity = 88/309 (28.48%), Postives = 160/309 (51.78%), Query Frame = 1 
Query:  118 DEEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDN---------SYLPNSNISEWIILYVKFN-YKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTLD-DSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAVV 1011
            D ++L   L+  ++  +RP +    T  V+V +   + Q++  +  ++  + + W    WQD++  W P   G +T++++PSE +WLPD+ +    NN D ++   + ++  + H G V W    I   SC +DV YFPFD QTC++    W     QI +  +      DN          Y P+    EW IL V    ++ Y       Y  I  +I ++R+ L++ + ++VP   +S L+ L+F L  DSG+++ + +S++LS TM+ +++S   P +   LP+L  YLL  + L+ +S V+ ++
Sbjct:   26 DAKRLYDDLLSNYNRLIRPVS--NNTDTVLVKLGLRLSQLIDLNLKDQILTTNVWLEHEWQDHKFRWDPAEYGGVTELYVPSEHIWLPDIVLY---NNADGEYVVTTMTKAVLHHTGKVVWTPPAIFKSSCEIDVRYFPFDQQTCFMKFGSWTYDGDQIDLKHINQKYD-DNKVKVGIDLREYYPS---VEWDILGVPAERHEKYYPCCAEPYPDIFFNITLRRKTLFYTVNLIVPCVGISYLSVLVFYLPADSGEKIALCISILLSQTMFFLLISEIIPSTSLALPLLGKYLLFTMVLVGLSVVITIM 325
[Close]
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. UniProt/SwissProt
Match: sp|P05376|ACHG_XENLA (Acetylcholine receptor subunit gamma OS=Xenopus laevis OX=8355 GN=chrng PE=2 SV=1)

HSP 1 Score: 142.51 bits (358), Expect = 5.245e-35
Identity = 92/315 (29.21%), Postives = 170/315 (53.97%), Query Frame = 1 
Query:  118 DEEKLITQLMKRHSLKVRPTACFQCTGAVI-VNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIIL---TPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYVK----FNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL--DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYL--LNQLGLLSVSTVLAVVNQKLR 1026
            +EE+L+  LMK ++  +RP    +  G +I V+I   +  +++ ++ EE  + + W  + W+DYRL+W P     I+ + +PS  +WLPDVG+    NN D  F     +   VS DG + W+   I   SCP+ V+YFPFD Q C I+    T   + ++ +L V  Q    ++      +   EW I ++      N++     +N  YQ I   + +QR+PL++II ++VP  ++S ++ L++ L     G + TV+++++L+ T+++ +V+   P +  ++P++  YL  L  + +  V+  + V+N  LR
Sbjct:   20 EEERLLNDLMKNYNKNLRPV---EKDGDIISVSIKLTLTNLISLNEKEEALTTNVWVEMQWKDYRLSWDPNDYHGISMMRIPSTSVWLPDVGL---ENNVDGTFDIALYTNTLVSSDGSMYWLPPAIYRSSCPVVVTYFPFDWQNCSIVFQSQTYSANEIELLLTVDEQTIEWIEIDPEAFTENGEWAIKHMPAKRIINHRLPRDDVN--YQQIVFYLIIQRKPLFYIINIIVPCVLISFVSILVYFLPAKAGGQKCTVSINILLAQTVFLFLVAQKIPETSTSVPLIVKYLTFLMVVTITIVANAVIVLNISLR 326
[Close]
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. UniProt/SwissProt
Match: sp|P43143|ACHA6_RAT (Neuronal acetylcholine receptor subunit alpha-6 OS=Rattus norvegicus OX=10116 GN=Chrna6 PE=2 SV=1)

HSP 1 Score: 140.198 bits (352), Expect = 2.358e-34
Identity = 88/333 (26.43%), Postives = 170/333 (51.05%), Query Frame = 1 
Query:   19 MLNVFGKFEIVAILSIFINSSRGAGFHDYSSFGDEEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVD-NSYLPNSNISEW-IILYVKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAV 1008
            MLN +G+ ++ + L ++I     A F        EE+L   L   ++  +RP      +  V V+    + Q+    +  +    + W    W+DYRL W P     I  + +P++ +W PD+ + N   N   DF  + +++  + +DG +TW    I   SCP+D+++FPFD Q C +    W     +I ++ +  GS VD N +  N   SEW I+    + +    +     Y  I+ S  ++R P+++ I +++P   +S L  L+F L  D G+++T+ +S++LS+T+++++++   P +   +P++  YLL  +  +++S V+ V
Sbjct:    1 MLNGWGRGDLRSGLCLWI-CGFLAFFKGSRGCVSEEQLFHTLFAHYNRFIRPVE--NVSDPVTVHFELAITQLANVDEVNQIMETNLWLRHVWKDYRLCWDPTEYDGIETLRVPADNIWKPDIVLYN---NAVGDFQVEGKTKALLKYDGVITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLII--GSKVDMNDFWEN---SEWEIVDASGYKHDIKYNCCEEIYTDITYSFYIRRLPMFYTINLIIPCLFISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLVGEYLLFTMIFVTLSIVVTV 322
[Close]
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. TrEMBL
Match: A0A4S2MMC4 (Neur_chan_LBD domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_000207 PE=3 SV=1)

HSP 1 Score: 439.499 bits (1129), Expect = 1.164e-141
Identity = 205/319 (64.26%), Postives = 256/319 (80.25%), Query Frame = 1 
Query:  106 SSFGDEEKLITQLMKRHSLKVRPTACF-QCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYVKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTLDDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAVVNQKLREKYRLSFWQDY 1059
             +   EEKL+ QL+ R SL VRP     + T  V V+ITYNVIQILAFSQAEET SISGWFT+ W+D RL W P+   +I +V +PS +LW+PDVGVMNG+++ DFDFSA  + R+++S  G VTW+HG +LD +CPLDV++FPFD QTC++ILTPWQS+ +Q+L+ P  HGS VDNSYLPNSN+SEW I  V F+ + Y S +N+TYQY+SI I ++RQPLYF++LVLVPFSMLS LACLIFTLDD+GDRL+VALSLVLSMTMYVVIVS+NAPRSMR LPVL I+LL+QLGLLS++TVLAV+N KL +   L  WQD+
Sbjct:   10 GTLSAEEKLVAQLLNRGSLTVRPNGHNNKTTSPVFVDITYNVIQILAFSQAEETMSISGWFTIKWRDPRLTWDPQEFSDIAEVNVPSGQLWIPDVGVMNGKSSTDFDFSAGVRGRLTLSSQGEVTWLHGAVLDTTCPLDVAFFPFDYQTCFLILTPWQSNEQQLLLRPFTHGSAVDNSYLPNSNVSEWEIQSVHFSSRKYRSDLNVTYQYVSIGIHLRRQPLYFVVLVLVPFSMLSALACLIFTLDDTGDRLSVALSLVLSMTMYVVIVSTNAPRSMRTLPVLGIFLLDQLGLLSIATVLAVINNKLYQATELMSWQDW 328
[Close]
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. TrEMBL
Match: A0A504YDR0 (Putative nachr subunit OS=Fasciola gigantica OX=46835 GN=FGIG_03463 PE=3 SV=1)

HSP 1 Score: 440.269 bits (1131), Expect = 4.911e-141
Identity = 211/318 (66.35%), Postives = 255/318 (80.19%), Query Frame = 1 
Query:  109 SFGDEEKLITQLMKRHSLKVRPTACF-QCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYVKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTLDDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAVVNQKLREKYRLSFWQDY 1059
            +F  EE+L+ QL+ R SL VRP     Q +  V VNITYNV+QILAFSQAEET SISGWFT+ W D RL+W P    NI +V +PS KLW+PDVGVMNG+++ DFDFSA  + R++V+ +G VTWMHG +LD +CPLDVS+FPFD QTC++ILTPWQS  +Q+L+ P  HGS VDNSYLPNSN+SEW I  V F+ K Y S +N+TYQY+SI I ++RQPLYF++LVLVPFSMLS LACLIFTLDD+GDRL+VALSLVLSMTMYVVIVSSNAPRSMR LPVL I+LL+QLGLLSV+TVLAV+N KL     L  W+D+
Sbjct:   91 TFMPEERLVAQLLHRRSLVVRPNGHNNQSSNPVHVNITYNVVQILAFSQAEETLSISGWFTIKWTDPRLSWDPHAFDNIREVNVPSSKLWIPDVGVMNGKSSTDFDFSAGVRGRLTVNWEGEVTWMHGAVLDTTCPLDVSFFPFDYQTCFLILTPWQSSEQQLLLRPFSHGSAVDNSYLPNSNVSEWEIQSVHFSSKKYRSDLNVTYQYVSIGIHLKRQPLYFVVLVLVPFSMLSALACLIFTLDDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRTLPVLGIFLLDQLGLLSVATVLAVINNKLFSSDELINWKDW 408
[Close]
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. TrEMBL
Match: V9TKF5 (Nicotinic acetylcholine receptor OS=Schistosoma mansoni OX=6183 PE=2 SV=1)

HSP 1 Score: 442.195 bits (1136), Expect = 5.399e-141
Identity = 210/318 (66.04%), Postives = 253/318 (79.56%), Query Frame = 1 
Query:  109 SFGDEEKLITQLMKRHSLKVRPTACF-QCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYVKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTLDDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAVVNQKLREKYRLSFWQDY 1059
            SF  EEKL+ QL+ R SL VRP     Q T  V VNITYNV+QIL FSQ+EET SISGWFT+ W D RL W P+    I +V LP+  LW+PDVGVMNG+ + DFDFSA  + R++VS+DG VTW+HG +LDV+CPLDVS+FPFD QTC++IL PWQS  +Q+L+ P  HGS VDNSYLPNSN+SEW I  V F  K Y S +N+TYQY+SI+I ++RQPLYFI+LVLVPFSMLS LACLIFTLDD+GDRL+VALSLVLSMTMYVVIVS+NAPRSMR LPVL I+LL+QLGLLS++T+LAV+N KL +   L  WQD+
Sbjct:   86 SFTAEEKLVAQLLNRGSLTVRPNGYMNQSTNPVHVNITYNVVQILGFSQSEETLSISGWFTMRWTDPRLTWDPEEFSEIQEVSLPTTNLWIPDVGVMNGKASTDFDFSAGVRGRVTVSNDGSVTWLHGAVLDVTCPLDVSFFPFDYQTCFLILVPWQSGEQQLLLQPFTHGSAVDNSYLPNSNVSEWEIQSVHFVRKKYRSDMNVTYQYVSIAIHLKRQPLYFIVLVLVPFSMLSALACLIFTLDDTGDRLSVALSLVLSMTMYVVIVSTNAPRSMRTLPVLGIFLLDQLGLLSIATILAVMNNKLYQSTELLNWQDF 403
[Close]
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. TrEMBL
Match: A0A4E0RUV1 (Neuronal acetylcholine receptor subunit alpha-6 OS=Fasciola hepatica OX=6192 GN=D915_003262 PE=3 SV=1)

HSP 1 Score: 439.884 bits (1130), Expect = 5.734e-141
Identity = 211/318 (66.35%), Postives = 255/318 (80.19%), Query Frame = 1 
Query:  109 SFGDEEKLITQLMKRHSLKVRPTACF-QCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYVKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTLDDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAVVNQKLREKYRLSFWQDY 1059
            +F  EE+L+ QL+ R SL VRP     Q +  V VNITYNV+QILAFSQAEET SISGWFT+ W D RL+W P    NI +V +PS KLW+PDVGVMNG+++ DFDFSA  + R++V+ +G VTWMHG +LD +CPLDVS+FPFD QTC++ILTPWQS  +Q+L+ P  HGS VDNSYLPNSN+SEW I  V F+ K Y S +N+TYQY+SI I ++RQPLYF++LVLVPFSMLS LACLIFTLDD+GDRL+VALSLVLSMTMYVVIVSSNAPRSMR LPVL I+LL+QLGLLSV+TVLAV+N KL     L  W+D+
Sbjct:   91 TFMPEERLVAQLLHRRSLVVRPNGHNNQSSNPVHVNITYNVVQILAFSQAEETLSISGWFTIKWTDPRLSWDPHAFDNIREVNVPSSKLWIPDVGVMNGKSSTDFDFSAGVRGRLTVNWEGEVTWMHGAVLDTTCPLDVSFFPFDYQTCFLILTPWQSSEQQLLLRPFSHGSAVDNSYLPNSNVSEWEIQSVHFSSKKYRSDLNVTYQYVSIGIHLKRQPLYFVVLVLVPFSMLSALACLIFTLDDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRTLPVLGIFLLDQLGLLSVATVLAVINNKLFSSDELINWKDW 408
[Close]
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. TrEMBL
Match: A0A3Q0KCD0 (Acetylcholine receptor-related OS=Schistosoma mansoni OX=6183 PE=3 SV=1)

HSP 1 Score: 442.195 bits (1136), Expect = 8.548e-141
Identity = 210/318 (66.04%), Postives = 253/318 (79.56%), Query Frame = 1 
Query:  109 SFGDEEKLITQLMKRHSLKVRPTACF-QCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYVKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTLDDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAVVNQKLREKYRLSFWQDY 1059
            SF  EEKL+ QL+ R SL VRP     Q T  V VNITYNV+QIL FSQ+EET SISGWFT+ W D RL W P+    I +V LP+  LW+PDVGVMNG+ + DFDFSA  + R++VS+DG VTW+HG +LDV+CPLDVS+FPFD QTC++IL PWQS  +Q+L+ P  HGS VDNSYLPNSN+SEW I  V F  K Y S +N+TYQY+SI+I ++RQPLYFI+LVLVPFSMLS LACLIFTLDD+GDRL+VALSLVLSMTMYVVIVS+NAPRSMR LPVL I+LL+QLGLLS++T+LAV+N KL +   L  WQD+
Sbjct:  101 SFTAEEKLVAQLLNRGSLTVRPNGYMNQSTNPVHVNITYNVVQILGFSQSEETLSISGWFTMRWTDPRLTWDPEEFSEIQEVSLPTTNLWIPDVGVMNGKASTDFDFSAGVRGRVTVSNDGSVTWLHGAVLDVTCPLDVSFFPFDYQTCFLILVPWQSGEQQLLLQPFTHGSAVDNSYLPNSNVSEWEIQSVHFVRKKYRSDMNVTYQYVSIAIHLKRQPLYFIVLVLVPFSMLSALACLIFTLDDTGDRLSVALSLVLSMTMYVVIVSTNAPRSMRTLPVLGIFLLDQLGLLSIATILAVMNNKLYQSTELLNWQDF 418
[Close]
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Cavefish
Match: chrnb1l (acetylcholine receptor subunit beta-like [Source:NCBI gene;Acc:103034907])

HSP 1 Score: 138.272 bits (347), Expect = 1.334e-34
Identity = 85/313 (27.16%), Postives = 169/313 (53.99%), Query Frame = 1 
Query:  121 EEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNI--------SEWIILYVKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAVVNQKLREK 1032
            E  L+  L + +++KVRP   +  T  V+V +   ++Q+++  Q     + + +  + W DYRL+W+P    NI  + +P  K+W PD+ ++   NN D  F       + V+ DG V+W+   I   SC ++V+YFPFD Q C ++    +S+      V +Q+G   D + L    I         EW I + K   K     +   Y+ I+  + ++R+PL++II ++VP  + S LA  +F L   +G+++T+++S+++++T+++++++   P +   +P++  Y++  + L++ S +L+VV   L  +
Sbjct:   27 ERSLLQDLFENYNVKVRPARVWNET--VMVRVGMTLVQLISLDQKNGEMTTNVYMNMAWTDYRLSWNPADYDNIDVIRIPPTKVWRPDIYLI---NNNDGQFDVALYVNVLVNSDGTVSWLPPAIYRSSCSIEVAYFPFDWQNCTMVF---RSYTYDASEVDLQYGLDEDGNELHEIVIDKNAFTENGEWQICH-KPTRKNIQEDL---YEDITFYLIIERKPLFYIINIIVPCILTSVLAIFVFYLPPGAGEKMTLSISVLIALTVFMLLLADKVPETSLAIPIIVNYVMFTMILVTFSVILSVVVLNLHHR 327
[Close]
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Cavefish
Match: chrna3 (neuronal acetylcholine receptor subunit alpha-3-like [Source:NCBI gene;Acc:103025148])

HSP 1 Score: 135.191 bits (339), Expect = 1.120e-33
Identity = 85/317 (26.81%), Postives = 164/317 (51.74%), Query Frame = 1 
Query:   64 IFINSSRGAGFHDYSSFGDEEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYVK-FNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAV 1008
            IFI  S G    +      E +L + +   ++  +RP      +  VIV    ++ Q++   +  +    + W    W DY+L W PK  G +  + +PS ++W PD+ +    NN   DF    +++  + ++G VTW+   I   SC +DV+YFPFD Q C +    W     +I +V +  GST++      S   EW+I+    + +    +     Y  I+ S+ ++R PL++ I +++P  ++S L  L+F L  D G+++T+ +S++LS+T+++++++   P +   +P++  YLL  +  +++S V+ V
Sbjct:   11 IFICFSAGGWASE-----AEHRLFSVIFSSYNQYIRPVE--NVSDPVIVQFEVSMSQLVKVDEVNQIMETNLWLRHIWNDYKLRWDPKDFGGVEFIRVPSNRIWKPDIVL---YNNAVGDFQVDDKTKALLRYNGDVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWTYDKAKIDLVLI--GSTINLKDFWESG--EWMIIDAPGYKHDIKYNCCEEIYTDITYSLYIRRLPLFYTINMIIPCLLISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITV 313
[Close]
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Cavefish
Match: chrne (acetylcholine receptor subunit gamma-like [Source:NCBI gene;Acc:103030399])

HSP 1 Score: 135.576 bits (340), Expect = 1.415e-33
Identity = 85/318 (26.73%), Postives = 162/318 (50.94%), Query Frame = 1 
Query:  109 SFGDEEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGST------VDNSYLPNSNISEWIILY--VKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL--DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGL--LSVSTVLAVVNQKLR 1026
            S  +E KLI    K ++  +RP         V V +   +  +++ ++ EET + + W  + W DYRL W+     +I+ + +P   +WLPD+ +    NN D  F     + + +  DG + W+   I   +C ++++YFPFD Q C ++         +I M+    G T      VD      +   EW I +   +    T  S  ++ YQ +  ++ +QR+PL++II +++P +++S L  L + L     G +LTV++S++L+ T+++++VS   P +  ++P++  YL+  + +  L V+  + V+N  LR
Sbjct:   25 SGNEESKLIADKFKNYNKNIRPAR--HTEDKVQVQVKLTLTNLISLNEKEETLTTNVWIEIQWNDYRLAWNTSDYHDISLIRVPYNTVWLPDIVL---ENNIDGKFDVAYYANVLIYSDGSMYWLPPAIYRSTCAIEITYFPFDWQNCTLVFRSQTYSANEIDMILAIDGDTQKPIEWVDIDPEAFTENGEWAIKHRPARKLTNTRYSPDDLEYQEVYFNLIIQRKPLFYIINIILPCALISSLVVLAYFLPAQAGGQKLTVSISVLLAQTVFLILVSQKVPETSLSVPLIGKYLIFVMSVTTLIVTNCIVVLNFSLR 337
[Close]
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Cavefish
Match: chrna4b (neuronal acetylcholine receptor subunit alpha-2 [Source:NCBI gene;Acc:103025036])

HSP 1 Score: 136.346 bits (342), Expect = 1.734e-33
Identity = 90/335 (26.87%), Postives = 175/335 (52.24%), Query Frame = 1 
Query:   70 INSSRGAGFHD-YSSFGDEEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYV--KFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAV----VNQKLREKYRLSFW 1050
            I ++ G+G    +S    EE+L+  L  R++   RP A    +  V+V+   ++ Q++   +  +  + + W    W DY+L W+P+   N+T + +PSE +W PD+ +    NN D DF+    ++  + HDG + W    I   SC +DV++FPFD Q C +    W     +I +V +      D   +      EW+I+    K+N K Y     I Y  I+ S  ++R PL++ I +++P  ++S L  L+F L  +  +++T+ +S++LS+T+++++++   P +   +P++  YLL  +  +++S ++ V    V+ +    +R+  W
Sbjct:   10 IQANVGSGMITIHSRAHAEERLLQVLFSRYNKLSRPVA--NISDVVLVHFGLSIAQLIDVDEKNQMMTTNVWVKQEWSDYKLRWNPEEYENVTSIRIPSELIWRPDIVLY---NNADGDFAVTHLTKAQLFHDGRIKWKPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDRAKIDLVSMDD----DVDQMDYWESGEWVIINAVGKYNTKKYECCTEI-YPDITYSFIIRRLPLFYTINLIIPCLLISCLTVLVFYLPSECAEKITLCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMIFVTLSIIITVFVLNVHHRSSRTHRMPHW 334
[Close]
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Cavefish
Match: chrnb2 (cholinergic receptor nicotinic beta 2 subunit [Source:NCBI gene;Acc:103045386])

HSP 1 Score: 135.961 bits (341), Expect = 1.809e-33
Identity = 92/327 (28.13%), Postives = 176/327 (53.82%), Query Frame = 1 
Query:   46 IVAILSIFINSSRGAGFHDYSSFGDEEKLITQLM--KRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYVKFNYKTYVSQ---INITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAV 1008
            +  +L   + SSRGA          EE+L+  L+    ++  +RP      +  V V +  ++ Q+++  + E+  + + W T  WQDYRL W P+    + +V LPS+ +WLPDV +    NN D  +     S   VSHDG V W+   I   +C ++V +FPFD Q C +    W     ++ +V     +++D+ + P+    EW I+ +        S    ++ITY +I     ++R+PL++ I +++P  +++ LA L+F L  D G+++T+ +S++L++T++++++S   P +  ++P++  YL+  + L++ S V +V
Sbjct:    7 LCILLLAIVQSSRGAD--------TEERLVEHLLNPAHYNKLIRPAT--NGSELVTVQLMVSLAQLISVHEREQIMTTNVWLTQEWQDYRLTWIPEEFDGMKKVRLPSKHIWLPDVVLY---NNADGMYEVSFYSNAVVSHDGSVFWLPPAIYKSACKIEVKHFPFDQQNCTLSFRSWTYDRTEVDLVLRSDVASMDD-FTPS---GEWDIIALPGRRNENPSDPTYVDITYDFI-----IRRKPLFYTINLIIPCVLITSLAILVFYLPSDCGEKMTLCISVLLALTVFLLLISKIVPPTSLDVPLVGKYLMFTMVLVTFSIVTSV 311
[Close]
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Sea Lamprey
Match: chrna3 (cholinergic receptor, nicotinic, alpha 3 [Source:ZFIN;Acc:ZDB-GENE-070822-1])

HSP 1 Score: 140.969 bits (354), Expect = 2.960e-36
Identity = 85/314 (27.07%), Postives = 168/314 (53.50%), Query Frame = 1 
Query:  127 KLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYVK-FNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAV----VNQKLREKYRLSFW 1050
            +L   L   ++  +RP   F  +  VIV    ++ Q++   +  +  + + W   TW DY+  W+P +   +  + +PS+K+W PD+ +    NN D DF  + +++  + +DG V WM   I   SC +DV+YFPFD Q C +    W     +I +V V  G+ ++      S   EW+I+ V  + +    +     Y  I+ S+ V+R PL++ I +++P  ++S L  L+F L  D G+++T+++S++LS+T+++++++   P +   +P++  YLL  +  +++S V+ +    V+ +  E + +  W
Sbjct:   10 RLYKTLFTSYNPYIRPV--FNVSDPVIVRFEVSMSQLVKLDEVNQIMATNLWLKHTWNDYKFQWNPGQFEGMEYIRVPSDKIWKPDIVL---YNNADGDFQVEGKTKALLKYDGTVMWMPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWTYDKAKIDLVLV--GTKINLKDFWESG--EWVIIDVPGYKHDIKYNCCEQIYPDITYSVYVRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCGEKVTLSISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITIFVLNVHYRTPEAHTMPNW 314
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BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Sea Lamprey
Match: chrnb3b (cholinergic receptor, nicotinic, beta 3b (neuronal) [Source:ZFIN;Acc:ZDB-GENE-030102-4])

HSP 1 Score: 130.183 bits (326), Expect = 1.060e-32
Identity = 79/301 (26.25%), Postives = 148/301 (49.17%), Query Frame = 1 
Query:  121 EEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPW--QSHVKQILMV--PVQHGSTVDNSYLPNSNISEWIILYVKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAV 1008
            E++L+ +++K +   VRP    + +  V V     + Q++   +  +  + + W    W D  L W+P   G I  + +P+  +WLPD+ + +   N D  F     ++  V HDG + W    I   SC +DV++FPFD Q C +    W     +  ++MV   V  G   DN         EW  L    N    +      Y YI+ S  ++R PL++ + ++VP   LS L   +F L  D G+++++  S+++S+T++++++    P S + +P++  YLL  +  +++S ++ V
Sbjct:   35 EDRLLKRMLKDYQKWVRPVD--KLSDTVEVKFGLGIAQLVDVDEKNQLMTTNVWLKQEWVDINLRWNPDDYGGINSIRVPASSIWLPDIVLYD---NADGRFEGSIVTKAVVKHDGRIKWTPPAIYKSSCTIDVTFFPFDQQNCSMKFGSWTYDGTLVDLIMVNSDVDRGEYFDN--------GEWEFLNATGNKGVRLDGHRF-YPYITYSFVIRRLPLFYTLFLIVPCLGLSFLTVFVFYLPSDEGEKISLCTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLLFIMIFVTLSIIITV 321
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BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Sea Lamprey
Match: chrna2a (cholinergic receptor, nicotinic, alpha 2a (neuronal) [Source:ZFIN;Acc:ZDB-GENE-040108-2])

HSP 1 Score: 118.242 bits (295), Expect = 2.697e-28
Identity = 72/246 (29.27%), Postives = 133/246 (54.07%), Query Frame = 1 
Query:  280 WFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYV--KFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAV 1008
            W    W DY+L W P    N+T + +PSE +W+PD+ + N   N D DF+    ++  + H G V W    I   SC +DV++FPFD Q C +    W     +I +V +     + + +       EW I++    +N K Y     + Y  I+ S  ++R PL++ I +++P  ++S L  L+F L  D G+++T+ +S++LS+T+++++++   P +   +P++  YLL  +  +++S V+ V
Sbjct:   25 WLKQEWDDYKLQWDPAEYENVTSIRVPSELIWVPDIVLYN---NADGDFAVTHMTKAHLFHTGRVRWKPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVSMARDVDLKDYW----ESGEWAIVHAVGTYNTKKYDCCPQV-YPDITYSFIIRRLPLFYTINLIIPCLLISCLTVLVFYLPSDCGEKITLCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMIFVTLSIVITV 262
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BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Sea Lamprey
Match: chrnb1l (cholinergic receptor, nicotinic, beta 1 (muscle) like [Source:ZFIN;Acc:ZDB-GENE-060811-1])

HSP 1 Score: 111.309 bits (277), Expect = 3.147e-26
Identity = 84/325 (25.85%), Postives = 167/325 (51.38%), Query Frame = 1 
Query:   70 INSSRGAGFHDYSSFGDEEKLITQL--MKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMV--------PVQHGSTVDNSYLPNSNISEWIILYVKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAVV 1011
            +N    AG     +   EE L+  L  ++++   VRP      TG V V +   + Q+++    +   ++S   +L+W+D RL+W P+   N+  + L  +++WLPD+ + N  N+ +FDF       + V + G V W+   I   SC + V YFPFD Q C ++   +     +I +          ++H   +D S  P S   EW I +      T  +  +  YQ I+  + ++R+PL++II ++VP  +++  A   F L  D+G+++ + +S++L++T+++++++   P +   +PV+  YL+  + +++   +L V+
Sbjct:   10 LNKCCSAGVRGLEA---EENLLKDLFVVQQYKTLVRPAR--TATGRVTVRLGMTLSQLISLPACQPDMTLSRLISLSWEDPRLSWDPRNYDNLRSIRLSPKRVWLPDIALSNN-NDGNFDFGLYVH--VLVDYTGAVRWVPPSIYRSSCGMQVKYFPFDWQNCSMVFQSFTYDTSEINLEYALDEHRQEIRH-IIIDESTFPVSG--EWQIKHKPSRKNT--NPRDPLYQDITFYLIMERKPLFYIINIVVPCILITICAVFTFYLPPDAGEKMGLCISVLLALTVFLLLLADKVPETSLGVPVIVNYLMFTMVIVTACVILTVI 321
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BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Sea Lamprey
Match: htr3a (5-hydroxytryptamine (serotonin) receptor 3A [Source:ZFIN;Acc:ZDB-GENE-071012-5])

HSP 1 Score: 90.8929 bits (224), Expect = 1.351e-19
Identity = 64/304 (21.05%), Postives = 140/304 (46.05%), Query Frame = 1 
Query:  130 LITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGV---MNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYVKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTLDDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAVVNQKLREK 1032
            L ++L   +   VRP   ++    +IV I   +  IL   +  +  +   W+   W D  L W P +   I Q+ +P+  +W+PD+ +   ++   + D  +       + +S++G V     + +  +C LD+  FPFD Q C +  T W      I +   +    +        N  EW ++ V       +   N  +  + I + ++R+PL++++ +++P + L  +    +   DSG+R++  ++L+L  ++++++V    P +    P++ +Y +  + LL +S +  +   +L  K
Sbjct:   38 LSSRLSSGYDKGVRPVKNWR--QPIIVAIDVMLYAILNVDEKNQVLTAYIWYRQRWTDEFLQWDPVQYDGIEQISIPTNNIWVPDIMISEFVDVGKSPDIGY-------VYLSYNGTVMNYKPLQVVSACSLDIYSFPFDVQNCTLTFTSWLHTSNDINLTLWRTTEEIKEDKSIFLNFGEWELISVPNELLHPLYGEN-RFSELKIYVVIRRRPLFYVVNLIMPSAFLMVMDAGFYLPPDSGERVSFKITLLLGYSVFLIVVQDTLPATPIGTPLIAVYFVVCMALLVISLMETIFIVRLVHK 331
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BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Nematostella
Match: EDO47631 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RLM5])

HSP 1 Score: 120.939 bits (302), Expect = 2.452e-30
Identity = 86/309 (27.83%), Postives = 157/309 (50.81%), Query Frame = 1 
Query:  121 EEKLITQLM--KRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYVKFNYKTYVSQINITYQY--ISISIRVQRQPLYFIILVLVPFSMLSGLACLIF-TLDDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVL-----CIYLLNQLGLLSVSTVLAVVNQ 1017
            E+ LI  L+   R+S + RP        A+++     +  I+A  +    F+ +    + W+D  L W+P   G +TQ+ L +  +W P V + N   +     ++ +  R  V  DG V WM   ++  SC +DV YFPFD Q C II   W   V ++ + P+  G      Y+ N   SEW +L      +T VS I    +   I+ S+ ++R+ LY+ +  ++P ++++ L  L+F T D++G+R+ V ++++LS+ ++ +++ +  P S + LP+L     CI +     L ++S VL  ++ 
Sbjct:    4 EDHLIRHLLNTTRYSPRFRPVR--DVKEALVLRHGMMLKTIVAVEEKNMVFTTNVRLRMGWKDAFLQWNPADYGGVTQINLEASDIWTPPVIIYNQAGDLGESITSSNTPRPVVRSDGTVLWMVPTVIKSSCVIDVKYFPFDQQLCKIIFGSWHYDVSKLDLQPLD-GKVDTTRYITN---SEWKLLSAT-AVRTQVSHICCRQEVARITYSLHIERRRLYYSMNFILPCTIIAFLMLLVFMTPDNTGERMAVGVTILLSLAVFFLMLETIMPIS-QMLPLLGKYYCCIIIEGAAALGAMSGVLRYIHH 304
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BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Nematostella
Match: EDO44896 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RUG1])

HSP 1 Score: 124.405 bits (311), Expect = 3.035e-30
Identity = 75/310 (24.19%), Postives = 158/310 (50.97%), Query Frame = 1 
Query:   85 GAGFHDYSSFGDEEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNI---SEW-IILYVKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTV 999
            G+  H+++  GD       L+K ++    P      T   +V     ++Q++      +  + + W    W +  L W P + G IT+V + + K+W+PD+ + N  +++      + ++R+ ++HDG   W        +C +DV++FPFD QTC++    W   V       V      D S L +S     +EW +I   K     Y +     +  ++++   +R+PL+++  ++VP  +++G+  L F L  +SG+R+T++++++L+M +++ + + N PR+  N+PVL I+ +  +  +++S +
Sbjct:    7 GSDLHEHTLLGD-------LLKGYNKDAHPVPILNKT-QYMVTFGLELVQLVNVDDKNQIITTNVWVRQRWTNLLLKWDPDKYGGITRVRIDASKIWIPDIVLYNSADSEFSGGLEKYKTRVILNHDGVNAWYSPASFRSTCQIDVTFFPFDQQTCFMKFGSWTFEV-------VDLDIFADKSPLHSSQYMKSAEWDLIAASKKRNVEYYACCTYPFSDVTVTWVFRRKPLFYVFNLIVPCLIITGMVLLGFMLPPESGERITLSITVLLAMAVFLQLAAENLPRNSDNVPVLGIFYITVMVEVALSLI 301
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BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Nematostella
Match: EDO49732 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RFJ2])

HSP 1 Score: 118.627 bits (296), Expect = 7.241e-30
Identity = 70/282 (24.82%), Postives = 144/282 (51.06%), Query Frame = 1 
Query:  118 DEEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHG--STVDNSYLPNSNISEWIILYVKFN-YKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTLD-DSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVL 951
            DEE+L   L + +  +   T     +  + V  + +++ +   ++ E++     W    W +  L W+P+  GNIT++ +P+  +W+PD+ + N         S    +++ ++ +G+ TW    I +  C LDV YFPFD QTC ++   W   + ++ +V        +  +S L   N  EW +++ K   Y+       I    ++IS+R+QR+  Y+++ +++P ++++    L F L  +SG+R+ + ++++LSM ++  + S   P S  + P+L
Sbjct:    3 DEERLFRFLFQGYKERRLVTPLRNRSEPITVVFSAHLLGLAKVNEKEQSIKTHLWIKEEWYNPFLMWNPEEFGNITEIIVPANMIWVPDIILYNKG-------STLFNTKVIIAFNGNNTWRSPAIYNTMCVLDVKYFPFDEQTCDLVFASWTRDISKLNLVTTSDTVPRSRRDSKLFQEN-EEWRVMFAKMKRYEVIFDWSEIPVADVTISVRLQRRTYYYVMNLILPCTLIACTIFLEFILPAESGERVGLGITILLSMAVFQELTSEKLPSSSEHFPLL 276
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BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Nematostella
Match: EDO49045 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RHV9])

HSP 1 Score: 119.398 bits (298), Expect = 1.401e-29
Identity = 78/289 (26.99%), Postives = 148/289 (51.21%), Query Frame = 1 
Query:  106 SSFGDEEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQ-SRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYVKFNYKTYVSQI--NITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTLD-DSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIY 960
            +S  DE++L+ +L+      VRP         V ++IT+N   I+   +  +  S S W   +W    L+W P   G + Q+ + S+ LW PD  V+     ++FD    +  +R+ V   G V W    +    C +DV+ FPFDSQ C I    WQ    ++ ++  +  +TV ++ + N    EW +  V    +    Q   N  Y  IS  I +QR+ L++++ +++P  +++ LA   F +  + G+R++  ++++LSMT+++++V+ + P +   +PV+ +Y
Sbjct:    7 ASATDEQRLLERLINASGSGVRPILDLARPTNVTLDITFN--SIIDVDEKHQILSSSVWIRQSWIAETLSWDPAEYGGVNQIVVSSQLLWQPDT-VLYNNIFEEFDSRLDTTVTRVRVYSSGFVYWAMPYVFKTMCKIDVTDFPFDSQRCPITFGAWQYDQNEVNLINNKRLATVASTRVEN---GEWTVEKVAIERRVIFYQCCPNQPYPEISFVIHMQRRSLFYVVNLVLPNFLITLLAFFSFFIPVECGERMSFVITVLLSMTVFLLLVAESIPPTSEAVPVIGVY 289
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BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Nematostella
Match: EDO42054 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S2J7])

HSP 1 Score: 120.168 bits (300), Expect = 5.576e-29
Identity = 74/297 (24.92%), Postives = 156/297 (52.53%), Query Frame = 1 
Query:  121 EEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPN-SNISEWIILYV--KFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTV 999
            E++L+  L + +  +VRP   F  +  V V  + ++IQI+A +   +  ++S W    W +  L W+  + G I  V L   K+W+PD+ + N  +        + ++ +  S DG   W        +C ++V YFPFDSQ C +    W     ++ M      ST D++ L    N  EW +L +  K N + + +     +  +++ + +QR+PLY++  +++P ++++ L  + F L  +SG+++ + ++++L+MT+++++V+   P +  ++P+L  Y +  + + ++S V
Sbjct:   38 EKRLLADLFRNYDSEVRPV--FNDSDKVNVEFSLSLIQIIAVNSKSQLVTVSVWIRQKWTNPMLAWNTSKYGGIESVNLNPAKVWIPDIILYNNADETYAGGLEKYKTSVIASSDGTQEWNSPASFTSTCNINVRYFPFDSQNCSLKFGSWTYVGNRLTMT-----STSDSADLSKYVNNGEWHLLAMPAKLN-RVFYNCCKYPFYDVTLYLEIQRKPLYYVFNLIIPCALIATLTLIKFFLPPESGEKVGLGITVLLAMTVFLLLVAETLPSTSDHIPLLGQYFVATMFVTAISLV 326
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BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Medaka
Match: ENSORLT00000017941.2 (neuronal acetylcholine receptor subunit alpha-3-like [Source:NCBI gene;Acc:101168601])

HSP 1 Score: 137.502 bits (345), Expect = 2.240e-34
Identity = 84/305 (27.54%), Postives = 159/305 (52.13%), Query Frame = 1 
Query:  100 DYSSFGDEEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEW-IILYVKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAV 1008
            D  S   E++L  +L +R++  +RP      +  V V    ++ Q++   +  +    + W    W DY+L W+P     I  + +PS K+W PD+ + N   N   DF  + +++  +  DG +TW+   I   SCP+D++YFPFD Q C +    W     +I +V +  GS V+      S   EW II    + +    +     Y  I+ S  ++R PL++ I +++P  ++S L  L+F L  D G+++T+ +S++LS+T+++++++   P +   +P++  YLL  +  +++S V+ V
Sbjct:   22 DCFSSKAEDRLFRKLFRRYNQFIRPVE--NVSDPVTVEFEVSISQLVKVDEVNQIMETNLWLRHIWNDYKLRWTPAEFDGIEFIRVPSNKIWRPDIVLYN---NAVGDFLVEDKTKALLKFDGTITWVPPAIFKSSCPMDITYFPFDYQNCSMKFGSWTYDKAKIDLVLI--GSKVNLKDFWESG--EWEIIDAPGYKHDIKYNCCEEIYPDITYSFYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITV 317
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BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Medaka
Match: chrna3 (neuronal acetylcholine receptor subunit alpha-3 [Source:NCBI gene;Acc:101159658])

HSP 1 Score: 136.346 bits (342), Expect = 1.309e-33
Identity = 81/298 (27.18%), Postives = 157/298 (52.68%), Query Frame = 1 
Query:  121 EEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYV-KFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAV 1008
            E KL + +   ++  +RP      +  VIV    ++ Q++   +  +    + W    W DY+L W+PK  G +  + +PS ++W PD+ +    NN   DF    +++  +  +G VTW+   I   SC +DV+YFPFD Q C +    W     +I +V +  GST++      S   EW I+    + +    +     Y  I+ S+ ++R PL++ I +++P  ++S L  L+F L  D G+++T+ +S++LS+T+++++++   P +   +P++  YLL  +  +++S V+ V
Sbjct:   28 EHKLFSVIFSNYNQYIRPVE--NVSDPVIVQFEVSMSQLVKVDEVNQIMETNLWLRHIWNDYKLKWNPKEFGGVEFIRVPSNRIWKPDIVLY---NNAVGDFQVDDKTKALLRFNGDVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWTYDKAKIDLVLI--GSTINLKDFWESG--EWTIIDAPGYKHDIKYNCCEEIYTDITYSLYIRRLPLFYTINMIIPCLLISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITV 316
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BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Medaka
Match: chrnb2 (cholinergic receptor nicotinic beta 2 subunit [Source:NCBI gene;Acc:101175346])

HSP 1 Score: 133.265 bits (334), Expect = 5.417e-33
Identity = 89/316 (28.16%), Postives = 175/316 (55.38%), Query Frame = 1 
Query:   82 RGAGFHDYSSFGD-EEKLITQLM--KRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYV---KFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAV 1008
            RG+ +H  S   D EE+L+  L+    ++  +RP      +  V V +  ++ Q+++  + E+  + + W T  WQDYRL W P+    + +V LPS+ +WLPDV +    NN D  +     S   VS+DG + W+   I   +C ++V +FPFD Q C +    W     +I +V     +++D+ + P+    EW I+ +   +       + ++ITY +I     ++R+PL++ I +++P  +++ LA L+F L  D G+++T+ +S++L++T++++++S   P +  ++P++  YL+  + L++ S V +V
Sbjct:   27 RGSFYHFCSLGADTEERLVEHLLNPAHYNKLIRPAT--NGSELVTVQLMVSLAQLISVHEREQVMTTNVWLTQEWQDYRLTWVPEEFDGMLKVRLPSKHIWLPDVVLY---NNADGVYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTLRFRSWTYDRTEIDLVLRADVASMDD-FTPS---GEWDIIALPGRRNENPADPAYVDITYDFI-----IRRKPLFYTINLIIPCVLITSLAILVFYLPSDCGEKMTLCISVLLALTVFLLLISKIVPPTSLDVPLVGKYLMFTMVLVTFSIVTSV 328
[Close]
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Medaka
Match: chrnd (cholinergic receptor nicotinic delta subunit [Source:NCBI gene;Acc:101164515])

HSP 1 Score: 132.494 bits (332), Expect = 1.735e-32
Identity = 87/323 (26.93%), Postives = 172/323 (53.25%), Query Frame = 1 
Query:   40 FEIVAILSIFINSSRGAGFHDYSSFGDEEKLITQLM--KRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYL-------PNS--NISEWIILY--VKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTLD-DSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLL 966
            F+   ++S F+ +   A   + S   +EE+LI  L   K+++ ++RP    Q    V V +   +  +++  +A+ET   + W   TW DYRL+W+      I  + LPS  +WLP++ +    NN D  F     S + V   G   W+   I   SC ++V+YFPFD Q C +  T    + K+I M+ ++  +  +N +        P S     EW I++   K N   ++   +  +Q I+  + ++R+PL++I+ +++P  ++S LA  ++ L  DSG+++T+++S++L+ +++++++S   P +  ++P++  YL+
Sbjct:    3 FQQAGLISAFLLTLLSA---ECSGRNEEERLINYLFLEKKYNKELRPVE--QHGDTVDVYLALTLSNLISLKEADETLLTNVWIDHTWIDYRLSWNVSEFDGIDMLRLPSNMVWLPEIVL---ENNNDAQFEVAYYSNVLVDPSGLCYWLPPAIFRSSCSINVNYFPFDWQNCTLKFTSLTYNAKEIRML-LKEDADEENKWTVEWIIIDPESFTENGEWEIIHRPAKRNTYKHIPMESNKHQDITFYLVIKRKPLFYIVNIIIPCVLISFLATFVYYLPADSGEKMTLSISVLLAQSVFLLLISQRLPETSMSVPLIVKYLM 316
[Close]
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Medaka
Match: chrnb1l (acetylcholine receptor subunit beta [Source:NCBI gene;Acc:101157009])

HSP 1 Score: 130.183 bits (326), Expect = 8.861e-32
Identity = 90/353 (25.50%), Postives = 183/353 (51.84%), Query Frame = 1 
Query:   16 IMLNVFGKFEIVAILSIFINSSRGAGFHDYSSFGDEEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQ----------HGSTVD-NSYLPNSNISEWIILY--VKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTL-DDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAVVNQKLREK 1032
            IM  +  KF +     +F+  S    F   S    E  L  +L + ++LKVRP   ++    V+V +   + Q+++ ++     + + +  + W DYRL+W P+   NI  + +P+ K+W PD+ ++   NN D  F       + V  DG + W+   I   +C +DV+YFPFD Q C ++   ++S+      V +Q          H   +D N++  N    EW I +   + N K      +  Y+ I+  + ++R+PL++II +++P  + S LA  +F L   +G+++T+++S+++++T+++++++   P +  + P++  Y++  + L++ S +L+VV   L  +
Sbjct:    4 IMGQMKMKFSVRTSFIVFVCISFCLAFTGASE--TERNLHQKLFQNYNLKVRPARYWE--EKVMVRVGMTLSQLVSLNEKNGEMTTNVYMNMQWSDYRLSWKPEEYDNIDVLRIPANKVWRPDIYLI---NNNDGHFDVALYVNVLVYSDGTINWLPPAIYRSACSIDVAYFPFDWQNCSMV---FRSYTYDASEVDLQYFLDDDGKEIHEIVIDENAFTEN---GEWAICHKPTRKNVK------DGLYEDITFYLIIERKPLFYIINIILPCILTSVLAIFVFYLPPGAGEKMTLSISVLIALTVFMLLLADKVPETSLSTPIIVNYVMFTMILVTFSVILSVVVLNLHHR 337
[Close]
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Planmine SMEST
Match: SMESG000061997.1 (SMESG000061997.1)

HSP 1 Score: 1073.54 bits (2775), Expect = 0.000e+0
Identity = 513/513 (100.00%), Postives = 513/513 (100.00%), Query Frame = 1 
Query:   16 IMLNVFGKFEIVAILSIFINSSRGAGFHDYSSFGDEEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYVKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTLDDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAVVNQKLREKYRLSFWQDYQQARTIFNGYYLEESPLMTDYCSDSPLATLKRAWQSQRYKNTKTETIFNSNAEDNLKSTQAYNSHRFKNIVKENDNPKSQPIKTNKDDRKHPPKSSFDDEGNKKRPFFNELFDSDQNHKGNIRQQRYYKKLANKLDRWELAIYLFISLINAIICLVLMPHYATEE 1554
            IMLNVFGKFEIVAILSIFINSSRGAGFHDYSSFGDEEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYVKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTLDDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAVVNQKLREKYRLSFWQDYQQARTIFNGYYLEESPLMTDYCSDSPLATLKRAWQSQRYKNTKTETIFNSNAEDNLKSTQAYNSHRFKNIVKENDNPKSQPIKTNKDDRKHPPKSSFDDEGNKKRPFFNELFDSDQNHKGNIRQQRYYKKLANKLDRWELAIYLFISLINAIICLVLMPHYATEE
Sbjct:  261 IMLNVFGKFEIVAILSIFINSSRGAGFHDYSSFGDEEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYVKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTLDDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAVVNQKLREKYRLSFWQDYQQARTIFNGYYLEESPLMTDYCSDSPLATLKRAWQSQRYKNTKTETIFNSNAEDNLKSTQAYNSHRFKNIVKENDNPKSQPIKTNKDDRKHPPKSSFDDEGNKKRPFFNELFDSDQNHKGNIRQQRYYKKLANKLDRWELAIYLFISLINAIICLVLMPHYATEE 773
[Close]
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Planmine SMEST
Match: SMESG000061997.1 (SMESG000061997.1)

HSP 1 Score: 1064.29 bits (2751), Expect = 0.000e+0
Identity = 512/512 (100.00%), Postives = 512/512 (100.00%), Query Frame = 1 
Query:   19 MLNVFGKFEIVAILSIFINSSRGAGFHDYSSFGDEEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYVKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTLDDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAVVNQKLREKYRLSFWQDYQQARTIFNGYYLEESPLMTDYCSDSPLATLKRAWQSQRYKNTKTETIFNSNAEDNLKSTQAYNSHRFKNIVKENDNPKSQPIKTNKDDRKHPPKSSFDDEGNKKRPFFNELFDSDQNHKGNIRQQRYYKKLANKLDRWELAIYLFISLINAIICLVLMPHYATEE 1554
            MLNVFGKFEIVAILSIFINSSRGAGFHDYSSFGDEEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYVKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTLDDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAVVNQKLREKYRLSFWQDYQQARTIFNGYYLEESPLMTDYCSDSPLATLKRAWQSQRYKNTKTETIFNSNAEDNLKSTQAYNSHRFKNIVKENDNPKSQPIKTNKDDRKHPPKSSFDDEGNKKRPFFNELFDSDQNHKGNIRQQRYYKKLANKLDRWELAIYLFISLINAIICLVLMPHYATEE
Sbjct:    1 MLNVFGKFEIVAILSIFINSSRGAGFHDYSSFGDEEKLITQLMKRHSLKVRPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYVKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTLDDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAVVNQKLREKYRLSFWQDYQQARTIFNGYYLEESPLMTDYCSDSPLATLKRAWQSQRYKNTKTETIFNSNAEDNLKSTQAYNSHRFKNIVKENDNPKSQPIKTNKDDRKHPPKSSFDDEGNKKRPFFNELFDSDQNHKGNIRQQRYYKKLANKLDRWELAIYLFISLINAIICLVLMPHYATEE 512
[Close]
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Planmine SMEST
Match: SMESG000077071.1 (SMESG000077071.1)

HSP 1 Score: 447.203 bits (1149), Expect = 6.454e-153
Identity = 228/343 (66.47%), Postives = 268/343 (78.13%), Query Frame = 1 
Query:  142 LMKR-HSLKVRPTAC-FQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYVKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTLDDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAVVNQKLREKYRLSFWQDYQQARTIFNGYYLEESPL---MTDYCSDSPLATLKR 1155
            LMK  + L VRP AC   C   VIVNITYNVIQILAFSQAEET  ISGWFT+ W D+RL W+PK  G+I  V L S+ LW PDVGVMNG+ ++DFDFS   QSR+SV H G++ W+HG ILDV+CPLDV YFPFD QTCY+ILTPWQS +KQ+++ PVQHGS VDNSYLPNSN+SEW I+ VKF+ KTY SQI+  YQ+ISISI ++RQPLYFI+LVLVPFSMLSGLACLIFTL D+GDRLTVALSLVLSMTMYVVIVS+NAPRSMR LPVL +YLLNQLGLLSV+T+LAVVN KLR+  R S         T  N  Y    P+     D C++SP+ +L++
Sbjct:    2 LMKSSNELTVRPNACRVHCNNPVIVNITYNVIQILAFSQAEETLKISGWFTVEWMDFRLRWNPKYYGDIDTVSLNSKNLWRPDVGVMNGKASEDFDFSNIPQSRISVKHTGNIYWLHGAILDVTCPLDVRYFPFDKQTCYLILTPWQSSIKQMVIEPVQHGSAVDNSYLPNSNVSEWEIVDVKFSKKTYESQISEVYQFISISISLKRQPLYFIVLVLVPFSMLSGLACLIFTLSDTGDRLTVALSLVLSMTMYVVIVSTNAPRSMRTLPVLGVYLLNQLGLLSVATILAVVNNKLRDNNRYS-----DMISTNPNEIY--RGPMNYRCYDQCNESPIKSLRK 337
[Close]
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Planmine SMEST
Match: SMESG000077071.1 (SMESG000077071.1)

HSP 1 Score: 446.432 bits (1147), Expect = 1.130e-152
Identity = 225/338 (66.57%), Postives = 265/338 (78.40%), Query Frame = 1 
Query:  154 HSLKVRPTAC-FQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYVKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTLDDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAVVNQKLREKYRLSFWQDYQQARTIFNGYYLEESPL---MTDYCSDSPLATLKR 1155
            + L VRP AC   C   VIVNITYNVIQILAFSQAEET  ISGWFT+ W D+RL W+PK  G+I  V L S+ LW PDVGVMNG+ ++DFDFS   QSR+SV H G++ W+HG ILDV+CPLDV YFPFD QTCY+ILTPWQS +KQ+++ PVQHGS VDNSYLPNSN+SEW I+ VKF+ KTY SQI+  YQ+ISISI ++RQPLYFI+LVLVPFSMLSGLACLIFTL D+GDRLTVALSLVLSMTMYVVIVS+NAPRSMR LPVL +YLLNQLGLLSV+T+LAVVN KLR+  R S         T  N  Y    P+     D C++SP+ +L++
Sbjct:    5 NELTVRPNACRVHCNNPVIVNITYNVIQILAFSQAEETLKISGWFTVEWMDFRLRWNPKYYGDIDTVSLNSKNLWRPDVGVMNGKASEDFDFSNIPQSRISVKHTGNIYWLHGAILDVTCPLDVRYFPFDKQTCYLILTPWQSSIKQMVIEPVQHGSAVDNSYLPNSNVSEWEIVDVKFSKKTYESQISEVYQFISISISLKRQPLYFIVLVLVPFSMLSGLACLIFTLSDTGDRLTVALSLVLSMTMYVVIVSTNAPRSMRTLPVLGVYLLNQLGLLSVATILAVVNNKLRDNNRYS-----DMISTNPNEIY--RGPMNYRCYDQCNESPIKSLRK 335
[Close]
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Planmine SMEST
Match: SMESG000043840.1 (SMESG000043840.1)

HSP 1 Score: 433.335 bits (1113), Expect = 1.330e-146
Identity = 245/475 (51.58%), Postives = 315/475 (66.32%), Query Frame = 1 
Query:  121 EEKLITQLMKRHSLKVRPTAC-FQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNWSPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDGHVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHGSTVDNSYLPNSNISEWIILYVKFNYKTYVSQINITYQYISISIRVQRQPLYFIILVLVPFSMLSGLACLIFTLDDSGDRLTVALSLVLSMTMYVVIVSSNAPRSMRNLPVLCIYLLNQLGLLSVSTVLAVVNQKLREKYRLSFWQDYQQARTIFNGYYLEESPLMTDYCSDSPLATLKRAWQSQRYKNTKTETIFNSNAEDNLKSTQAYNSHRFKNIVKENDNPKSQPIKTNKDDRKHPPKSSFDDEGNKKRPFFNELFDSDQNHKGNIRQQRYYKKLANKLDRWELAIYLFISLINAIICLVLMPHY 1542
            EE+L+  L KR+ LKVRP  C   C   V VNITYNVIQILAFSQAEET SISGWFT+ W D RL W+ ++ GN+  V +P++ +WLPD+G+MN +N+K+FDFS  +QSR+SV  DG +TW+HG ILDV+CPLDV +FPFD QTCY+++TPWQS  KQ+L+ P Q GS VDNSYLPNSN+SEW I  V F  K Y S +N+TYQYI +SI ++RQPLYF++LVL+PFSMLSGLACLIFTL+D+GDRL+VALSLVLSMTMYVVIVSSNAPRSMR+LPV+ IYLL+QLGLLS++TVLAV+N K+R  +++S      ++R    GY   E      Y +DSP+  L+ +       N K    FN  A+ N   + A NS R    V       +  +  N         + F        P +              R    YK LA++ D+ E+  YL IS IN + CL+++P Y
Sbjct:   26 EEELLNILRKRN-LKVRPNPCRSHCANPVNVNITYNVIQILAFSQAEETMSISGWFTIVWSDNRLEWNSEKYGNLNAVSIPAQDMWLPDIGIMNVKNSKNFDFSTIAQSRISVESDGRITWLHGAILDVTCPLDVRFFPFDVQTCYLVITPWQSSDKQMLIHPYQLGSAVDNSYLPNSNVSEWEIRAVHFKRKRYRSDLNVTYQYIRVSIHLRRQPLYFVVLVLIPFSMLSGLACLIFTLEDTGDRLSVALSLVLSMTMYVVIVSSNAPRSMRSLPVIGIYLLDQLGLLSLATVLAVINNKVR-YFKVS---PESKSRKQPTGYRCPE------YNNDSPIIQLQNSKNRMNDANHKINKKFN--ADYNFSKSYANNSVRVNFNV-------ANSLSRNSSPSTSLSSTDF-------LPLYQP------------RGVNIYKDLADRFDKIEMVTYLIISFINGVFCLIVVPSY 461
The following BLAST results are available for this feature:
BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CHRNA31.418e-3325.50cholinergic receptor nicotinic alpha 3 subunit [So... [more]
CHRNA61.776e-3326.76cholinergic receptor nicotinic alpha 6 subunit [So... [more]
CHRND2.475e-3327.85cholinergic receptor nicotinic delta subunit [Sour... [more]
CHRNA33.900e-3325.50cholinergic receptor nicotinic alpha 3 subunit [So... [more]
CHRNA33.900e-3325.50cholinergic receptor nicotinic alpha 3 subunit [So... [more]
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BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
acr-211.851e-3325.39pep chromosome:WBcel235:III:6581927:6586549:1 gene... [more]
acr-212.930e-3325.39pep chromosome:WBcel235:III:6581927:6586549:1 gene... [more]
acr-154.168e-3225.59AcetylCholine Receptor [Source:UniProtKB/TrEMBL;A... [more]
acr-214.914e-3225.50pep chromosome:WBcel235:III:6583461:6586549:1 gene... [more]
unc-295.218e-3225.70Acetylcholine receptor subunit beta-type unc-29 [... [more]
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BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
nAChRalpha21.779e-3727.83gene:FBgn0000039 transcript:FBtr0084639[more]
nAChRalpha21.779e-3727.83gene:FBgn0000039 transcript:FBtr0084640[more]
nAChRalpha14.697e-3126.09gene:FBgn0000036 transcript:FBtr0330310[more]
nAChRalpha15.314e-3126.09gene:FBgn0000036 transcript:FBtr0334916[more]
nAChRalpha15.314e-3126.09gene:FBgn0000036 transcript:FBtr0084619[more]
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BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
chrne4.046e-3426.88cholinergic receptor, nicotinic, epsilon [Source:Z... [more]
chrne4.046e-3426.88cholinergic receptor, nicotinic, epsilon [Source:Z... [more]
chrnb1l6.107e-3427.03cholinergic receptor, nicotinic, beta 1 (muscle) l... [more]
chrnb1l8.043e-3426.97cholinergic receptor, nicotinic, beta 1 (muscle) l... [more]
chrnb1l1.387e-3326.90cholinergic receptor, nicotinic, beta 1 (muscle) l... [more]
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BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ncaph8.986e-3828.43non-SMC condensin I complex subunit H [Source:Xenb... [more]
ncaph1.296e-3728.43non-SMC condensin I complex subunit H [Source:Xenb... [more]
ncaph1.359e-3728.43non-SMC condensin I complex subunit H [Source:Xenb... [more]
ncaph2.272e-3728.43non-SMC condensin I complex subunit H [Source:Xenb... [more]
ncaph2.310e-3728.43non-SMC condensin I complex subunit H [Source:Xenb... [more]
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BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Chrna38.527e-3526.17cholinergic receptor, nicotinic, alpha polypeptide... [more]
Chrna61.042e-3426.45cholinergic receptor, nicotinic, alpha polypeptide... [more]
Chrna31.345e-3426.17cholinergic receptor, nicotinic, alpha polypeptide... [more]
Chrna31.379e-3426.17cholinergic receptor, nicotinic, alpha polypeptide... [more]
Chrnd2.102e-3327.85cholinergic receptor, nicotinic, delta polypeptide... [more]
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BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P17644|ACH2_DROME1.783e-3627.83Acetylcholine receptor subunit alpha-like 2 OS=Dro... [more]
sp|P25110|ACHD_RAT7.802e-3629.11Acetylcholine receptor subunit delta OS=Rattus nor... [more]
sp|P23414|ACH1_SCHGR1.104e-3528.48Acetylcholine receptor subunit alpha-L1 OS=Schisto... [more]
sp|P05376|ACHG_XENLA5.245e-3529.21Acetylcholine receptor subunit gamma OS=Xenopus la... [more]
sp|P43143|ACHA6_RAT2.358e-3426.43Neuronal acetylcholine receptor subunit alpha-6 OS... [more]
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BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A4S2MMC41.164e-14164.26Neur_chan_LBD domain-containing protein OS=Opistho... [more]
A0A504YDR04.911e-14166.35Putative nachr subunit OS=Fasciola gigantica OX=46... [more]
V9TKF55.399e-14166.04Nicotinic acetylcholine receptor OS=Schistosoma ma... [more]
A0A4E0RUV15.734e-14166.35Neuronal acetylcholine receptor subunit alpha-6 OS... [more]
A0A3Q0KCD08.548e-14166.04Acetylcholine receptor-related OS=Schistosoma mans... [more]
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BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
chrnb1l1.334e-3427.16acetylcholine receptor subunit beta-like [Source:N... [more]
chrna31.120e-3326.81neuronal acetylcholine receptor subunit alpha-3-li... [more]
chrne1.415e-3326.73acetylcholine receptor subunit gamma-like [Source:... [more]
chrna4b1.734e-3326.87neuronal acetylcholine receptor subunit alpha-2 [S... [more]
chrnb21.809e-3328.13cholinergic receptor nicotinic beta 2 subunit [Sou... [more]
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BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
chrna32.960e-3627.07cholinergic receptor, nicotinic, alpha 3 [Source:Z... [more]
chrnb3b1.060e-3226.25cholinergic receptor, nicotinic, beta 3b (neuronal... [more]
chrna2a2.697e-2829.27cholinergic receptor, nicotinic, alpha 2a (neurona... [more]
chrnb1l3.147e-2625.85cholinergic receptor, nicotinic, beta 1 (muscle) l... [more]
htr3a1.351e-1921.055-hydroxytryptamine (serotonin) receptor 3A [Sourc... [more]
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BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO476312.452e-3027.83Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO448963.035e-3024.19Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO497327.241e-3024.82Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO490451.401e-2926.99Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO420545.576e-2924.92Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSORLT00000017941.22.240e-3427.54neuronal acetylcholine receptor subunit alpha-3-li... [more]
chrna31.309e-3327.18neuronal acetylcholine receptor subunit alpha-3 [S... [more]
chrnb25.417e-3328.16cholinergic receptor nicotinic beta 2 subunit [Sou... [more]
chrnd1.735e-3226.93cholinergic receptor nicotinic delta subunit [Sour... [more]
chrnb1l8.861e-3225.50acetylcholine receptor subunit beta [Source:NCBI g... [more]
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BLAST of Neuronal acetylcholine receptor subunit alpha-6 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000061997.10.000e+0100.00SMESG000061997.1[more]
SMESG000061997.10.000e+0100.00SMESG000061997.1[more]
SMESG000077071.16.454e-15366.47SMESG000077071.1[more]
SMESG000077071.11.130e-15266.57SMESG000077071.1[more]
SMESG000043840.11.330e-14651.58SMESG000043840.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30019169 ID=SMED30019169|Name=Neuronal acetylcholine receptor subunit alpha-6|organism=Schmidtea mediterranea sexual|type=transcript|length=1893bp
CTACAATTTATGTAGATTATGTTAAACGTATTTGGAAAATTTGAGATTGT
GGCTATTTTATCCATTTTCATCAATTCATCACGGGGGGCAGGTTTTCATG
ATTATTCAAGTTTTGGTGACGAAGAAAAACTTATCACACAACTTATGAAG
CGTCACAGCCTTAAAGTTAGGCCAACTGCTTGTTTCCAATGTACTGGAGC
CGTCATTGTAAACATTACTTATAATGTTATACAGATTTTGGCATTTTCTC
AAGCAGAGGAAACTTTCAGTATATCCGGTTGGTTCACATTGACTTGGCAA
GATTACAGGTTAAATTGGTCTCCAAAACGTAATGGCAATATCACTCAAGT
TTTCCTTCCTTCTGAAAAGTTATGGTTACCGGATGTAGGGGTAATGAATG
GAAGAAATAATAAAGATTTTGATTTCAGCGCACAATCTCAATCAAGGATG
AGTGTTAGCCATGACGGCCATGTCACCTGGATGCACGGAGTAATACTCGA
TGTCAGTTGTCCTTTAGATGTATCGTATTTTCCTTTTGATTCTCAAACTT
GCTACATCATTCTTACTCCTTGGCAAAGCCATGTAAAGCAGATTCTCATG
GTACCAGTACAGCACGGATCAACAGTAGATAACAGTTACCTACCAAATTC
AAACATTAGTGAATGGATTATTTTATACGTCAAATTCAATTACAAAACCT
ACGTCAGCCAAATAAATATTACCTACCAATATATAAGCATCAGCATAAGA
GTTCAGAGGCAGCCCCTTTATTTTATAATATTAGTCTTAGTTCCTTTTTC
AATGTTATCTGGACTTGCGTGCCTTATATTTACTCTTGATGACTCAGGAG
ACAGATTGACAGTAGCCTTATCTCTCGTTCTCAGTATGACAATGTACGTT
GTAATTGTATCTTCAAATGCTCCAAGGTCCATGAGAAATCTTCCAGTTCT
ATGCATTTATTTGTTAAATCAACTCGGTCTTCTCAGTGTCTCTACGGTTC
TGGCAGTGGTCAATCAGAAACTAAGGGAAAAATACAGATTGTCATTTTGG
CAAGATTACCAGCAAGCACGTACAATTTTCAATGGATATTATTTGGAAGA
ATCGCCTTTGATGACAGATTACTGCTCCGATAGCCCTTTGGCTACTTTGA
AACGTGCTTGGCAAAGTCAGCGCTATAAGAACACAAAAACCGAAACCATA
TTCAATTCGAATGCTGAGGATAACCTTAAGTCTACTCAAGCGTATAATTC
GCACAGATTTAAGAATATTGTTAAGGAAAATGATAATCCGAAATCTCAGC
CAATTAAAACAAACAAAGATGATCGAAAGCACCCGCCGAAGTCATCATTT
GATGATGAAGGAAACAAAAAACGGCCATTTTTCAATGAACTTTTCGACAG
TGATCAGAATCATAAGGGTAACATCCGCCAGCAAAGATATTACAAAAAGC
TGGCTAATAAACTTGATAGATGGGAATTAGCAATTTATTTGTTTATATCT
TTGATAAACGCGATAATTTGTCTAGTTCTAATGCCGCATTATGCGACTGA
GGAATGATGAGATATTTCAAAGAAAAATTTGTAGATTTTGCTTAAATTTT
GTAGATTTTTCTTCCACTAAGCTAATAAAATTTATAATTATTTTTAGAAT
CTATCAAATACGAATTTAGAGAAAATCAAGGCTATTTATTGAGTAACAAA
AAAATAAAAAATGATTAATGCTGCCAAAATAATTTATAGACGCTATATTC
ACGTAGCACCGTTACAGACAATTACAAACCTATGTATTGATTATTCTATA
AATGTCAGCAAGATTCTATGCATACAAATCGTATCAAATTGAAAACAAAT
AATATATTATACATTATTTCTGCAAACCAATTTATTTGATCAG
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protein sequence of SMED30019169-orf-1

>SMED30019169-orf-1 ID=SMED30019169-orf-1|Name=SMED30019169-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=513bp
MLNVFGKFEIVAILSIFINSSRGAGFHDYSSFGDEEKLITQLMKRHSLKV
RPTACFQCTGAVIVNITYNVIQILAFSQAEETFSISGWFTLTWQDYRLNW
SPKRNGNITQVFLPSEKLWLPDVGVMNGRNNKDFDFSAQSQSRMSVSHDG
HVTWMHGVILDVSCPLDVSYFPFDSQTCYIILTPWQSHVKQILMVPVQHG
STVDNSYLPNSNISEWIILYVKFNYKTYVSQINITYQYISISIRVQRQPL
YFIILVLVPFSMLSGLACLIFTLDDSGDRLTVALSLVLSMTMYVVIVSSN
APRSMRNLPVLCIYLLNQLGLLSVSTVLAVVNQKLREKYRLSFWQDYQQA
RTIFNGYYLEESPLMTDYCSDSPLATLKRAWQSQRYKNTKTETIFNSNAE
DNLKSTQAYNSHRFKNIVKENDNPKSQPIKTNKDDRKHPPKSSFDDEGNK
KRPFFNELFDSDQNHKGNIRQQRYYKKLANKLDRWELAIYLFISLINAII
CLVLMPHYATEE*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0004888transmembrane signaling receptor activity
GO:0005216ion channel activity
GO:0005230extracellular ligand-gated ion channel activity
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000034epidermis
PLANA:0000418head
PLANA:0002032epidermal cell
Vocabulary: INTERPRO
TermDefinition
IPR036734Neur_chan_lig-bd_sf
IPR036719Neuro-gated_channel_TM_sf
IPR006201Neur_channel
IPR027361Acetylcholine_rcpt_TM
IPR006029Neurotrans-gated_channel_TM
IPR006202Neur_chan_lig-bd
IPR018000Neurotransmitter_ion_chnl_CS
Vocabulary: biological process
TermDefinition
GO:0006811ion transport
GO:0006810transport
GO:0034220ion transmembrane transport
Vocabulary: cellular component
TermDefinition
GO:0016021integral component of membrane
GO:0016020membrane
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR006201Neurotransmitter-gated ion-channelPRINTSPR00252NRIONCHANNELcoord: 53..69
score: 33.43
coord: 133..147
score: 53.7
coord: 86..97
score: 39.03
coord: 212..224
score: 28.89
IPR006201Neurotransmitter-gated ion-channelPANTHERPTHR18945NEUROTRANSMITTER GATED ION CHANNELcoord: 6..471
IPR006202Neurotransmitter-gated ion-channel ligand-binding domainPFAMPF02931Neur_chan_LBDcoord: 4..218
e-value: 1.0E-40
score: 139.5
NoneNo IPR availableGENE3DG3DSA:1.20.58.390coord: 221..328
e-value: 4.4E-15
score: 57.8
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 389..416
NoneNo IPR availablePANTHERPTHR18945:SF778ACETYLCHOLINE RECEPTOR SUBUNIT BETA-LIKE 2coord: 6..471
NoneNo IPR availableCDDcd18989LGIC_ECD_cationcoord: 31..217
e-value: 1.4564E-51
score: 171.006
NoneNo IPR availableCDDcd19051LGIC_TM_cationcoord: 219..313
e-value: 2.63193E-15
score: 69.6989
NoneNo IPR availableTMHMMTMhelixcoord: 249..268
NoneNo IPR availableTMHMMTMhelixcoord: 278..300
NoneNo IPR availableTMHMMTMhelixcoord: 220..242
NoneNo IPR availableTMHMMTMhelixcoord: 456..478
IPR006029Neurotransmitter-gated ion-channel transmembrane domainPFAMPF02932Neur_chan_membcoord: 226..468
e-value: 3.5E-10
score: 40.3
IPR036734Neurotransmitter-gated ion-channel ligand-binding domain superfamilyGENE3DG3DSA:2.70.170.10coord: 4..220
e-value: 2.4E-46
score: 159.8
IPR036734Neurotransmitter-gated ion-channel ligand-binding domain superfamilySUPERFAMILYSSF63712Nicotinic receptor ligand binding domain-likecoord: 3..218
IPR018000Neurotransmitter-gated ion-channel, conserved sitePROSITEPS00236NEUROTR_ION_CHANNELcoord: 133..147
IPR036719Neurotransmitter-gated ion-channel transmembrane domain superfamilySUPERFAMILYSSF90112Neurotransmitter-gated ion-channel transmembrane porecoord: 218..477