Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6

Overview
NameBifunctional arginine demethylase and lysyl-hydroxylase JMJD6
Smed IDSMED30019142
Length (bp)1007
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 (SMED30019142) t-SNE clustered cells

Violin plots show distribution of expression levels for Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 (SMED30019142) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 (SMED30019142) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 (SMED30019142) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30019142

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 5

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30019142SMESG000039333.1 SmedASXL_010312SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
reproductive organSMED30019142SMESG000039333.1 Contig11079newmark_estsPMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30019142SMESG000039333.1 Contig11079uc_Smed_v2PMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30019142SMESG000039333.1 Contig7165newmark_estsPMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30019142SMESG000039333.1 Contig7165uc_Smed_v2PMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. Ensembl Human
Match: JMJD6 (jumonji domain containing 6, arginine demethylase and lysine hydroxylase [Source:HGNC Symbol;Acc:HGNC:19355])

HSP 1 Score: 284.648 bits (727), Expect = 2.933e-93
Identity = 135/240 (56.25%), Postives = 178/240 (74.17%), Query Frame = 2 
Query:  101 YRNQSFRCGDDENDRTVSIKMKYFADYMKNNNDDSPLYVFDGSLDENKKKARLLEDYQVSGYFTEDLFSILGDKIRPPFRWFVIGSARSGSNIHIDPLGTSAWNALVHGYKRWCLFPPCTPKFLVKPPINKNWGRLTEASDWFNIMYKRMLLSDWPSEYAMTEAIQKPGETIFVPSGWWHVVLNLTTTVAITQNFCSTINFPIVWRKTVXXXXXXXXXXXXXXXEIRPDLCEIADEINVN 820
            YRNQ F+CG+D +  +V +KMKY+ +YM++  DDSPLY+FD S  E+ K+ +LLEDY+V  +FT+DLF   G+K RPP+RWFV+G  RSG+ IHIDPLGTSAWNALV G+KRWCLFP  TP+ L+K   ++   +  EA  WFN++Y R  L  WP E+   E +QKPGET+FVP GWWHVVLNL TT+AITQNF S+ NFP+VW KTV+ R KLS+ WY+ L +  P+L  +AD +++ 
Sbjct:   94 YRNQKFKCGEDNDGYSVKMKMKYYIEYMESTRDDSPLYIFDSSYGEHPKRRKLLEDYKVPKFFTDDLFQYAGEKRRPPYRWFVMGPPRSGTGIHIDPLGTSAWNALVQGHKRWCLFPTSTPRELIKVTRDEGGNQQDEAITWFNVIYPRTQLPTWPPEFKPLEILQKPGETVFVPGGWWHVVLNLDTTIAITQNFASSTNFPVVWHKTVRGRPKLSRKWYRILKQEHPELAVLADSVDLQ 333
[Close]
BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. Ensembl Human
Match: JMJD6 (jumonji domain containing 6, arginine demethylase and lysine hydroxylase [Source:HGNC Symbol;Acc:HGNC:19355])

HSP 1 Score: 284.648 bits (727), Expect = 5.014e-93
Identity = 135/240 (56.25%), Postives = 178/240 (74.17%), Query Frame = 2 
Query:  101 YRNQSFRCGDDENDRTVSIKMKYFADYMKNNNDDSPLYVFDGSLDENKKKARLLEDYQVSGYFTEDLFSILGDKIRPPFRWFVIGSARSGSNIHIDPLGTSAWNALVHGYKRWCLFPPCTPKFLVKPPINKNWGRLTEASDWFNIMYKRMLLSDWPSEYAMTEAIQKPGETIFVPSGWWHVVLNLTTTVAITQNFCSTINFPIVWRKTVXXXXXXXXXXXXXXXEIRPDLCEIADEINVN 820
            YRNQ F+CG+D +  +V +KMKY+ +YM++  DDSPLY+FD S  E+ K+ +LLEDY+V  +FT+DLF   G+K RPP+RWFV+G  RSG+ IHIDPLGTSAWNALV G+KRWCLFP  TP+ L+K   ++   +  EA  WFN++Y R  L  WP E+   E +QKPGET+FVP GWWHVVLNL TT+AITQNF S+ NFP+VW KTV+ R KLS+ WY+ L +  P+L  +AD +++ 
Sbjct:   94 YRNQKFKCGEDNDGYSVKMKMKYYIEYMESTRDDSPLYIFDSSYGEHPKRRKLLEDYKVPKFFTDDLFQYAGEKRRPPYRWFVMGPPRSGTGIHIDPLGTSAWNALVQGHKRWCLFPTSTPRELIKVTRDEGGNQQDEAITWFNVIYPRTQLPTWPPEFKPLEILQKPGETVFVPGGWWHVVLNLDTTIAITQNFASSTNFPVVWHKTVRGRPKLSRKWYRILKQEHPELAVLADSVDLQ 333
[Close]
BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. Ensembl Human
Match: JMJD6 (jumonji domain containing 6, arginine demethylase and lysine hydroxylase [Source:HGNC Symbol;Acc:HGNC:19355])

HSP 1 Score: 280.026 bits (715), Expect = 2.891e-92
Identity = 124/209 (59.33%), Postives = 158/209 (75.60%), Query Frame = 2 
Query:  101 YRNQSFRCGDDENDRTVSIKMKYFADYMKNNNDDSPLYVFDGSLDENKKKARLLEDYQVSGYFTEDLFSILGDKIRPPFRWFVIGSARSGSNIHIDPLGTSAWNALVHGYKRWCLFPPCTPKFLVKPPINKNWGRLTEASDWFNIMYKRMLLSDWPSEYAMTEAIQKPGETIFVPSGWWHVVLNLTTTVAITQNFCSTINFPIVWRKTV 727
            YRNQ F+CG+D +  +V +KMKY+ +YM++  DDSPLY+FD S  E+ K+ +LLEDY+V  +FT+DLF   G+K RPP+RWFV+G  RSG+ IHIDPLGTSAWNALV G+KRWCLFP  TP+ L+K   ++   +  EA  WFN++Y R  L  WP E+   E +QKPGET+FVP GWWHVVLNL TT+AITQNF S+ NFP+VW KTV
Sbjct:   94 YRNQKFKCGEDNDGYSVKMKMKYYIEYMESTRDDSPLYIFDSSYGEHPKRRKLLEDYKVPKFFTDDLFQYAGEKRRPPYRWFVMGPPRSGTGIHIDPLGTSAWNALVQGHKRWCLFPTSTPRELIKVTRDEGGNQQDEAITWFNVIYPRTQLPTWPPEFKPLEILQKPGETVFVPGGWWHVVLNLDTTIAITQNFASSTNFPVVWHKTV 302
[Close]
BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. Ensembl Human
Match: JMJD6 (jumonji domain containing 6, arginine demethylase and lysine hydroxylase [Source:HGNC Symbol;Acc:HGNC:19355])

HSP 1 Score: 279.641 bits (714), Expect = 7.055e-92
Identity = 124/209 (59.33%), Postives = 158/209 (75.60%), Query Frame = 2 
Query:  101 YRNQSFRCGDDENDRTVSIKMKYFADYMKNNNDDSPLYVFDGSLDENKKKARLLEDYQVSGYFTEDLFSILGDKIRPPFRWFVIGSARSGSNIHIDPLGTSAWNALVHGYKRWCLFPPCTPKFLVKPPINKNWGRLTEASDWFNIMYKRMLLSDWPSEYAMTEAIQKPGETIFVPSGWWHVVLNLTTTVAITQNFCSTINFPIVWRKTV 727
            YRNQ F+CG+D +  +V +KMKY+ +YM++  DDSPLY+FD S  E+ K+ +LLEDY+V  +FT+DLF   G+K RPP+RWFV+G  RSG+ IHIDPLGTSAWNALV G+KRWCLFP  TP+ L+K   ++   +  EA  WFN++Y R  L  WP E+   E +QKPGET+FVP GWWHVVLNL TT+AITQNF S+ NFP+VW KTV
Sbjct:   94 YRNQKFKCGEDNDGYSVKMKMKYYIEYMESTRDDSPLYIFDSSYGEHPKRRKLLEDYKVPKFFTDDLFQYAGEKRRPPYRWFVMGPPRSGTGIHIDPLGTSAWNALVQGHKRWCLFPTSTPRELIKVTRDEGGNQQDEAITWFNVIYPRTQLPTWPPEFKPLEILQKPGETVFVPGGWWHVVLNLDTTIAITQNFASSTNFPVVWHKTV 302
[Close]
BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. Ensembl Human
Match: JMJD6 (jumonji domain containing 6, arginine demethylase and lysine hydroxylase [Source:HGNC Symbol;Acc:HGNC:19355])

HSP 1 Score: 279.641 bits (714), Expect = 7.055e-92
Identity = 124/209 (59.33%), Postives = 158/209 (75.60%), Query Frame = 2 
Query:  101 YRNQSFRCGDDENDRTVSIKMKYFADYMKNNNDDSPLYVFDGSLDENKKKARLLEDYQVSGYFTEDLFSILGDKIRPPFRWFVIGSARSGSNIHIDPLGTSAWNALVHGYKRWCLFPPCTPKFLVKPPINKNWGRLTEASDWFNIMYKRMLLSDWPSEYAMTEAIQKPGETIFVPSGWWHVVLNLTTTVAITQNFCSTINFPIVWRKTV 727
            YRNQ F+CG+D +  +V +KMKY+ +YM++  DDSPLY+FD S  E+ K+ +LLEDY+V  +FT+DLF   G+K RPP+RWFV+G  RSG+ IHIDPLGTSAWNALV G+KRWCLFP  TP+ L+K   ++   +  EA  WFN++Y R  L  WP E+   E +QKPGET+FVP GWWHVVLNL TT+AITQNF S+ NFP+VW KTV
Sbjct:   94 YRNQKFKCGEDNDGYSVKMKMKYYIEYMESTRDDSPLYIFDSSYGEHPKRRKLLEDYKVPKFFTDDLFQYAGEKRRPPYRWFVMGPPRSGTGIHIDPLGTSAWNALVQGHKRWCLFPTSTPRELIKVTRDEGGNQQDEAITWFNVIYPRTQLPTWPPEFKPLEILQKPGETVFVPGGWWHVVLNLDTTIAITQNFASSTNFPVVWHKTV 302
[Close]
BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. Ensembl Celegans
Match: psr-1 (Bifunctional arginine demethylase and lysyl-hydroxylase psr-1 [Source:UniProtKB/Swiss-Prot;Acc:Q9GYI4])

HSP 1 Score: 264.618 bits (675), Expect = 7.889e-86
Identity = 133/233 (57.08%), Postives = 163/233 (69.96%), Query Frame = 2 
Query:  101 YRNQSFRCGDDENDRTVSIKMKYFADYMKNNNDDSPLYVFDGSLDENKKKARLLEDYQVSGYFTEDLFSILGDKIRPPFRWFVIGSARSGSNIHIDPLGTSAWNALVHGYKRWCLFPPCTPKFLVKPPINKNWGRLTEASDWFNIMYKRMLLSDWPSEYAMTEAIQKPGETIFVPSGWWHVVLNLTTTVAITQNFCSTINFPIVWRKTVXXXXXXXXXXXXXXXEIRPDLCEI 799
            YRNQ+F+CG+D+N  +V +KMKY+ DYM NN DDSPLY+FD S  E +K  +L EDY V  +F +DLF    DK RPP RWFV+G ARSG+ IHIDPLGTSAWN+L+ G+KRW L PP  P+ LVKP  ++      E   WF  +YKR+    WP EYA  E  Q PGET+FVPSGWWHVV+N   T+A+T N+CS  N  +VW KTVK R KLSK W K+L E RP+L EI
Sbjct:   99 YRNQNFKCGEDDNGNSVRMKMKYYHDYMLNNKDDSPLYIFDSSFAERRKTKKLSEDYSVPKFFEDDLFHYADDKKRPPHRWFVMGPARSGTAIHIDPLGTSAWNSLLQGHKRWVLIPPIAPRDLVKPMAHEKGKHPDEGITWFQTVYKRVRSPSWPKEYAPIECRQGPGETMFVPSGWWHVVINEEYTIAVTHNYCSVENLHLVWPKTVKGRPKLSKHWVKRLTEQRPELLEI 331
[Close]
BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. Ensembl Celegans
Match: psr-1 (Bifunctional arginine demethylase and lysyl-hydroxylase psr-1 [Source:UniProtKB/Swiss-Prot;Acc:Q9GYI4])

HSP 1 Score: 264.618 bits (675), Expect = 1.191e-85
Identity = 133/233 (57.08%), Postives = 163/233 (69.96%), Query Frame = 2 
Query:  101 YRNQSFRCGDDENDRTVSIKMKYFADYMKNNNDDSPLYVFDGSLDENKKKARLLEDYQVSGYFTEDLFSILGDKIRPPFRWFVIGSARSGSNIHIDPLGTSAWNALVHGYKRWCLFPPCTPKFLVKPPINKNWGRLTEASDWFNIMYKRMLLSDWPSEYAMTEAIQKPGETIFVPSGWWHVVLNLTTTVAITQNFCSTINFPIVWRKTVXXXXXXXXXXXXXXXEIRPDLCEI 799
            YRNQ+F+CG+D+N  +V +KMKY+ DYM NN DDSPLY+FD S  E +K  +L EDY V  +F +DLF    DK RPP RWFV+G ARSG+ IHIDPLGTSAWN+L+ G+KRW L PP  P+ LVKP  ++      E   WF  +YKR+    WP EYA  E  Q PGET+FVPSGWWHVV+N   T+A+T N+CS  N  +VW KTVK R KLSK W K+L E RP+L EI
Sbjct:  115 YRNQNFKCGEDDNGNSVRMKMKYYHDYMLNNKDDSPLYIFDSSFAERRKTKKLSEDYSVPKFFEDDLFHYADDKKRPPHRWFVMGPARSGTAIHIDPLGTSAWNSLLQGHKRWVLIPPIAPRDLVKPMAHEKGKHPDEGITWFQTVYKRVRSPSWPKEYAPIECRQGPGETMFVPSGWWHVVINEEYTIAVTHNYCSVENLHLVWPKTVKGRPKLSKHWVKRLTEQRPELLEI 347
[Close]
BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. Ensembl Celegans
Match: psr-1 (Bifunctional arginine demethylase and lysyl-hydroxylase psr-1 [Source:UniProtKB/Swiss-Prot;Acc:Q9GYI4])

HSP 1 Score: 239.965 bits (611), Expect = 8.858e-78
Identity = 123/215 (57.21%), Postives = 148/215 (68.84%), Query Frame = 2 
Query:  155 IKMKYFADYMKNNNDDSPLYVFDGSLDENKKKARLLEDYQVSGYFTEDLFSILGDKIRPPFRWFVIGSARSGSNIHIDPLGTSAWNALVHGYKRWCLFPPCTPKFLVKPPINKNWGRLTEASDWFNIMYKRMLLSDWPSEYAMTEAIQKPGETIFVPSGWWHVVLNLTTTVAITQNFCSTINFPIVWRKTVXXXXXXXXXXXXXXXEIRPDLCEI 799
            +KMKY+ DYM NN DDSPLY+FD S  E +K  +L EDY V  +F +DLF    DK RPP RWFV+G ARSG+ IHIDPLGTSAWN+L+ G+KRW L PP  P+ LVKP  ++      E   WF  +YKR+    WP EYA  E  Q PGET+FVPSGWWHVV+N   T+A+T N+CS  N  +VW KTVK R KLSK W K+L E RP+L EI
Sbjct:    1 MKMKYYHDYMLNNKDDSPLYIFDSSFAERRKTKKLSEDYSVPKFFEDDLFHYADDKKRPPHRWFVMGPARSGTAIHIDPLGTSAWNSLLQGHKRWVLIPPIAPRDLVKPMAHEKGKHPDEGITWFQTVYKRVRSPSWPKEYAPIECRQGPGETMFVPSGWWHVVINEEYTIAVTHNYCSVENLHLVWPKTVKGRPKLSKHWVKRLTEQRPELLEI 215
[Close]
BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. Ensembl Celegans
Match: jmjd-4 (JuMonJi (Transcription factor) Domain protein [Source:UniProtKB/TrEMBL;Acc:Q14V35])

HSP 1 Score: 64.3142 bits (155), Expect = 2.908e-11
Identity = 40/155 (25.81%), Postives = 80/155 (51.61%), Query Frame = 2 
Query:  269 YQVSGYFTEDLFSI---LGDKIRPPF----RWFVIGSARSGSNIHIDPLGTSAWNALVHGYKRWCLFPPCTPKFLVKPPINKNWGRLTEASDWFNIMYKRMLLSDWPSEYAMTEAIQKPGETIFVPSGWWHVVLNLTTTVAITQNFCSTINFPIV 712
            Y +  +F+ D  +      +K   PF    R+  IG++ S + +H D + + +W+A + G K+W + PP +   L +  + ++ G + +  +     Y+R+       +  + + +Q+PGE +FVPS W+H   NL  T++I  N+ ++ N  +V
Sbjct:  108 YSLHPFFSRDFVNCEPWTSEKSENPFGDDYRFVYIGASGSWTKLHSDVVSSHSWSANICGRKQWFMMPPGSEN-LFRSSVTES-GFVDDIRE-----YERLF-----EQAKVIKFVQEPGEIVFVPSNWYHQAHNLEDTISINHNWMNSTNLHLV 250
[Close]
BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. Ensembl Celegans
Match: C27F2.9 (pep chromosome:WBcel235:III:4961817:4963092:-1 gene:WBGene00043156.1 transcript:C27F2.9.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:C27F2.9)

HSP 1 Score: 51.9878 bits (123), Expect = 1.856e-7
Identity = 33/111 (29.73%), Postives = 50/111 (45.05%), Query Frame = 2 
Query:  344 FVIGSARSGSNIHIDPLGTSAWNALVHGYKRWCLFPPCTPKFLVKPPINKNWGRLTEASDWFNIMYKRMLLSDWPSEYAMTEAIQKPGETIFVPSGWWHVVLNLTTTVAIT 676
            F I  A +G   H    G +    ++HG KRW L+P     +  +P    NW       +W+   Y ++   + P E  M     K GE I+ P  WWH  LN+ ++V I+
Sbjct:  162 FGIAGAGTGVPFHFHGPGFAE---VIHGSKRWFLYP-----YEQRP----NWNPDKTTLEWYTYDYPKLSRDELPLECEM-----KSGEVIYFPDKWWHATLNIESSVFIS 255
[Close]
BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. Ensembl Fly
Match: PSR (gene:FBgn0038948 transcript:FBtr0084239)

HSP 1 Score: 271.552 bits (693), Expect = 2.079e-88
Identity = 131/240 (54.58%), Postives = 168/240 (70.00%), Query Frame = 2 
Query:  101 YRNQSFRCGDDENDRTVSIKMKYFADYMKNNNDDSPLYVFDGSLDENKKKARLLEDYQVSGYFTEDLFSILGDKIRPPFRWFVIGSARSGSNIHIDPLGTSAWNALVHGYKRWCLFPPCTPKFLVKPPINKNWGRLTEASDWFNIMYKRMLLSDWPSEYAMTEAIQKPGETIFVPSGWWHVVLNLTTTVAITQNFCSTINFPIVWRKTVXXXXXXXXXXXXXXXEIRPDLCEIADEINVN 820
            YRNQ F+CG+D    +V +KMKY+ +YM++  DDSPLY+FD S  E+ ++ +LL+DY V  YF +DLF   G+  RPP+RWFV+G ARSG+ IHIDPLGTSAWN L+ G+KRWCLFP  TPK L+K        +  EA  WF+ +Y R  L  WP +Y   E +Q  GET+FVP GWWHVVLN+  T+AITQNF S  NFP VW KTV+ R KLS+ W + L + RP+L +IAD IN+N
Sbjct:   99 YRNQKFKCGEDNEGYSVKMKMKYYVEYMQSTRDDSPLYIFDSSFGEHHRRRKLLDDYVVPKYFRDDLFQYCGENRRPPYRWFVMGPARSGTGIHIDPLGTSAWNTLIRGHKRWCLFPTQTPKELLKVTSAMGGKQRDEAITWFSTIYPRTQLPSWPEQYRPIEVLQGAGETVFVPGGWWHVVLNMDDTIAITQNFSSQTNFPCVWHKTVRGRPKLSRKWLRVLRDQRPELAQIADSINLN 338
[Close]
BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. Ensembl Fly
Match: PSR (gene:FBgn0038948 transcript:FBtr0330378)

HSP 1 Score: 272.322 bits (695), Expect = 3.055e-88
Identity = 131/240 (54.58%), Postives = 168/240 (70.00%), Query Frame = 2 
Query:  101 YRNQSFRCGDDENDRTVSIKMKYFADYMKNNNDDSPLYVFDGSLDENKKKARLLEDYQVSGYFTEDLFSILGDKIRPPFRWFVIGSARSGSNIHIDPLGTSAWNALVHGYKRWCLFPPCTPKFLVKPPINKNWGRLTEASDWFNIMYKRMLLSDWPSEYAMTEAIQKPGETIFVPSGWWHVVLNLTTTVAITQNFCSTINFPIVWRKTVXXXXXXXXXXXXXXXEIRPDLCEIADEINVN 820
            YRNQ F+CG+D    +V +KMKY+ +YM++  DDSPLY+FD S  E+ ++ +LL+DY V  YF +DLF   G+  RPP+RWFV+G ARSG+ IHIDPLGTSAWN L+ G+KRWCLFP  TPK L+K        +  EA  WF+ +Y R  L  WP +Y   E +Q  GET+FVP GWWHVVLN+  T+AITQNF S  NFP VW KTV+ R KLS+ W + L + RP+L +IAD IN+N
Sbjct:   99 YRNQKFKCGEDNEGYSVKMKMKYYVEYMQSTRDDSPLYIFDSSFGEHHRRRKLLDDYVVPKYFRDDLFQYCGENRRPPYRWFVMGPARSGTGIHIDPLGTSAWNTLIRGHKRWCLFPTQTPKELLKVTSAMGGKQRDEAITWFSTIYPRTQLPSWPEQYRPIEVLQGAGETVFVPGGWWHVVLNMDDTIAITQNFSSQTNFPCVWHKTVRGRPKLSRKWLRVLRDQRPELAQIADSINLN 338
[Close]
BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. Ensembl Fly
Match: JMJD4 (gene:FBgn0032671 transcript:FBtr0081062)

HSP 1 Score: 67.781 bits (164), Expect = 2.882e-12
Identity = 44/151 (29.14%), Postives = 74/151 (49.01%), Query Frame = 2 
Query:  269 YQVSGYFTED-LFSILGDKIRPPFRWFVIGSARSGSNIHIDPLGTSAWNALVHGYKRWCLFPPCTPKFLVKPPINKNWGRLTEASDWFNIMYKRMLLSDWPSEYAMTEAIQKPGETIFVPSGWWHVVLNLTTTVAITQNFCSTINFPIVWR 718
            Y+V  YF  D L   L  + +  +R+  +G   S ++ H D  G+ +W+  + G K+W + PP       +  +N   G L  + D      ++ML       Y +    Q+  E +FVPSGW+H V NLT T+++  N+ +  N  +VW+
Sbjct:  174 YKVPKYFASDWLNEQLIQQGKDDYRFVYMGPKNSWTSYHADVFGSFSWSTNIVGLKKWLIMPPGE-----ELKLNDRLGNLPFSID------EKMLDEHNVRYYTIN---QRANEAVFVPSGWFHQVWNLTDTISVNHNWFNGCNISMVWQ 310
[Close]
BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. Ensembl Fly
Match: JMJD4 (gene:FBgn0032671 transcript:FBtr0343823)

HSP 1 Score: 67.781 bits (164), Expect = 2.882e-12
Identity = 44/151 (29.14%), Postives = 74/151 (49.01%), Query Frame = 2 
Query:  269 YQVSGYFTED-LFSILGDKIRPPFRWFVIGSARSGSNIHIDPLGTSAWNALVHGYKRWCLFPPCTPKFLVKPPINKNWGRLTEASDWFNIMYKRMLLSDWPSEYAMTEAIQKPGETIFVPSGWWHVVLNLTTTVAITQNFCSTINFPIVWR 718
            Y+V  YF  D L   L  + +  +R+  +G   S ++ H D  G+ +W+  + G K+W + PP       +  +N   G L  + D      ++ML       Y +    Q+  E +FVPSGW+H V NLT T+++  N+ +  N  +VW+
Sbjct:  174 YKVPKYFASDWLNEQLIQQGKDDYRFVYMGPKNSWTSYHADVFGSFSWSTNIVGLKKWLIMPPGE-----ELKLNDRLGNLPFSID------EKMLDEHNVRYYTIN---QRANEAVFVPSGWFHQVWNLTDTISVNHNWFNGCNISMVWQ 310
[Close]
BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. Ensembl Zebrafish
Match: jmjd6 (jumonji domain containing 6, arginine demethylase and lysine hydroxylase [Source:NCBI gene;Acc:266962])

HSP 1 Score: 290.812 bits (743), Expect = 7.184e-96
Identity = 137/240 (57.08%), Postives = 181/240 (75.42%), Query Frame = 2 
Query:  101 YRNQSFRCGDDENDRTVSIKMKYFADYMKNNNDDSPLYVFDGSLDENKKKARLLEDYQVSGYFTEDLFSILGDKIRPPFRWFVIGSARSGSNIHIDPLGTSAWNALVHGYKRWCLFPPCTPKFLVKPPINKNWGRLTEASDWFNIMYKRMLLSDWPSEYAMTEAIQKPGETIFVPSGWWHVVLNLTTTVAITQNFCSTINFPIVWRKTVXXXXXXXXXXXXXXXEIRPDLCEIADEINVN 820
            YRNQ F+CG+D +  +V +KMKY+ +Y+++ +DDSPLY+FD S  E+ K+ +LLEDYQV  +F +DLF   G+K RPP+RWFV+G ARSG+ IHIDPLGTSAWNALV G+KRWCLFP  TP+ L+K   ++   +  EA  WFN++Y R   S WP E+   E +Q+PGET+FVP GWWHVVLNL TT+A+TQNF ST NFPIVW KTV+ R KLS+ WY+ L + RPD+  IAD++++ 
Sbjct:   94 YRNQKFKCGEDNDGYSVKMKMKYYVEYLESTHDDSPLYIFDSSFGEHAKRRKLLEDYQVPLFFRDDLFQFAGEKRRPPYRWFVMGPARSGTGIHIDPLGTSAWNALVQGHKRWCLFPTHTPRELIKVTRDEGGNQQDEAITWFNVIYPRTQQSTWPDEFRPLEILQRPGETVFVPGGWWHVVLNLDTTIAVTQNFASTTNFPIVWHKTVRGRPKLSRKWYRILKQERPDIAAIADKVDLQ 333
[Close]
BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. Ensembl Zebrafish
Match: jmjd4 (jumonji domain containing 4 [Source:NCBI gene;Acc:767690])

HSP 1 Score: 73.1738 bits (178), Expect = 5.914e-14
Identity = 54/190 (28.42%), Postives = 90/190 (47.37%), Query Frame = 2 
Query:  161 MKYFADYMKNNNDDSP---LYVFDGSLDENKKKARLLEDYQVSGYFTEDLFSILGDKIR-PPFRWFVIGSARSGSNIHIDPLGTSAWNALVHGYKRWCLFPPCTPKFLVKPPINKNWGRLTEASDWFNIMYKRMLLSDWPSEYAMTEAIQKPGETIFVPSGWWHVVLNLTTTVAITQNFCSTINFPIVWR 718
            ++Y+ + ++N +  SP   LY+ D  +  N  +  +   Y+   YF+ D  +   D I    +R+  +G   S +  H D   + +W+A + G K+W L+PP    FL     N  +           I+  + L + +       E IQ+ GE IFVPSGW H V NL  T++I  N+ +  N  I+W+
Sbjct:  113 IQYWRESIQNGHS-SPKGCLYLKDWHMQRNFPEHNI---YKTPIYFSSDWLNEYWDTIEVDDYRFVYMGPKGSWTPFHADVFRSYSWSANICGRKKWLLYPPGQEDFLRDCHGNLAYDVTAP------ILQDKGLYAQFEEACQPLEIIQEAGEIIFVPSGWHHQVYNLEDTISINHNWLNGCNLDIMWQ 292
[Close]
BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. Ensembl Zebrafish
Match: JMJD8 (jumonji domain containing 8 [Source:NCBI gene;Acc:100330060])

HSP 1 Score: 47.7506 bits (112), Expect = 4.598e-6
Identity = 36/130 (27.69%), Postives = 58/130 (44.62%), Query Frame = 2 
Query:  305 SILGDKIRPPFRW------FVIGSARSGSNIHIDPLGTSAWNALVHGYKRWCLFPPCTPKFLVKPPINKNWGRLTEASDWFNIMYKRMLLSDWPSEYAMTEAIQKPGETIFVPSGWWHVVLNLTTTVAIT 676
            S+  +   PPF        +  G A  G+ +     G   ++ +++G KRW L+PP      + P  + N   L+    W +  Y  + L   P E  +     +PGE ++ P  WWH  LNL T+V I+
Sbjct:   89 SLFEEYKAPPFSLPLTHPAYSFGIAGPGTGVPFHWHG-PGYSEVIYGRKRWFLYPPD-----LAPEFHPNHTTLS----WVSQSYLDLELHQRPLECTI-----RPGEVLYFPDRWWHATLNLDTSVFIS 203
[Close]
BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. Ensembl Xenopus
Match: jmjd6 (jumonji domain containing 6 [Source:NCBI gene;Acc:548957])

HSP 1 Score: 278.87 bits (712), Expect = 5.848e-91
Identity = 131/240 (54.58%), Postives = 175/240 (72.92%), Query Frame = 2 
Query:  101 YRNQSFRCGDDENDRTVSIKMKYFADYMKNNNDDSPLYVFDGSLDENKKKARLLEDYQVSGYFTEDLFSILGDKIRPPFRWFVIGSARSGSNIHIDPLGTSAWNALVHGYKRWCLFPPCTPKFLVKPPINKNWGRLTEASDWFNIMYKRMLLSDWPSEYAMTEAIQKPGETIFVPSGWWHVVLNLTTTVAITQNFCSTINFPIVWRKTVXXXXXXXXXXXXXXXEIRPDLCEIADEINVN 820
            YRNQ F+CG+D +  +V +KMKY+ +Y++   DDSPLY+FD S  E+ K+ +LLEDY+V  YF +DLF   G+K RPP+RWFV+G ARSG+ IHIDPLGTSAWN+LVHG+KRWCLFP   P+ L+K   ++   +  EA  WF ++Y R  L  WP ++   E +QKPGET+FVP GWWHVVLNL T +A+TQNF S  NFP+VW KTV+ R KLS+ WY+ L + RP+L  +AD +++ 
Sbjct:   94 YRNQKFKCGEDNDGYSVKMKMKYYIEYLEGTRDDSPLYIFDSSYGEHPKRKKLLEDYEVPKYFRDDLFQFAGEKRRPPYRWFVMGPARSGTGIHIDPLGTSAWNSLVHGHKRWCLFPTNVPRELIKVTRDEGGNQQDEAITWFTVIYPRTQLPSWPPDFKPLEILQKPGETVFVPGGWWHVVLNLDTAIAVTQNFASCSNFPVVWHKTVRGRPKLSRKWYRILKQERPELAALADTVDLQ 333
[Close]
BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. Ensembl Xenopus
Match: lman2 (lectin, mannose-binding 2 [Source:Xenbase;Acc:XB-GENE-5934286])

HSP 1 Score: 69.3218 bits (168), Expect = 1.463e-12
Identity = 56/189 (29.63%), Postives = 88/189 (46.56%), Query Frame = 2 
Query:  161 MKYFADYMKNN--NDDSPLYVFDGSLDENKKKARLLE--DYQVSGYFTEDLFSILGDKIRPPFRWFVIGSARSGSNIHIDPLGTSAWNALVHGYKRWCLFPPCTPKFLVKPPINKNWGRLTEASDWFNIMYKRMLLSDWPSEYAMTEAIQKPGETIFVPSGWWHVVLNLTTTVAITQNFCSTINFPIVW 715
            + Y+ DY ++N  +    LY+ D  +     +  + E  +Y  S +  E   +I GD     +R+  +G   S +  H D   + +W+A V G K+W LFPP   + L     N  +  +T A     I Y  +     PSE      IQ+ G+ IF+PSGW H V NL  T++I  N+ +  N   +W
Sbjct:   95 ISYWRDYAEHNCCSPRGCLYLKDWHMRREFPEQNVYETPEYFASDWLNEYWDAIDGDD----YRFVYMGPKGSWTPFHADVFRSYSWSANVCGRKKWLLFPPGQEEHLRDSHGNLPYD-VTSAGLRDPIQYPHLSQCCRPSE-----VIQEAGQVIFIPSGWHHQVYNLEDTISINHNWINGCNVSAMW 273
[Close]
BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. Ensembl Xenopus
Match: lman2 (lectin, mannose-binding 2 [Source:Xenbase;Acc:XB-GENE-5934286])

HSP 1 Score: 69.3218 bits (168), Expect = 1.475e-12
Identity = 56/189 (29.63%), Postives = 88/189 (46.56%), Query Frame = 2 
Query:  161 MKYFADYMKNN--NDDSPLYVFDGSLDENKKKARLLE--DYQVSGYFTEDLFSILGDKIRPPFRWFVIGSARSGSNIHIDPLGTSAWNALVHGYKRWCLFPPCTPKFLVKPPINKNWGRLTEASDWFNIMYKRMLLSDWPSEYAMTEAIQKPGETIFVPSGWWHVVLNLTTTVAITQNFCSTINFPIVW 715
            + Y+ DY ++N  +    LY+ D  +     +  + E  +Y  S +  E   +I GD     +R+  +G   S +  H D   + +W+A V G K+W LFPP   + L     N  +  +T A     I Y  +     PSE      IQ+ G+ IF+PSGW H V NL  T++I  N+ +  N   +W
Sbjct:   95 ISYWRDYAEHNCCSPRGCLYLKDWHMRREFPEQNVYETPEYFASDWLNEYWDAIDGDD----YRFVYMGPKGSWTPFHADVFRSYSWSANVCGRKKWLLFPPGQEEHLRDSHGNLPYD-VTSAGLRDPIQYPHLSQCCRPSE-----VIQEAGQVIFIPSGWHHQVYNLEDTISINHNWINGCNVSAMW 273
[Close]
BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. Ensembl Xenopus
Match: lman2 (lectin, mannose-binding 2 [Source:Xenbase;Acc:XB-GENE-5934286])

HSP 1 Score: 69.3218 bits (168), Expect = 1.595e-12
Identity = 56/189 (29.63%), Postives = 88/189 (46.56%), Query Frame = 2 
Query:  161 MKYFADYMKNN--NDDSPLYVFDGSLDENKKKARLLE--DYQVSGYFTEDLFSILGDKIRPPFRWFVIGSARSGSNIHIDPLGTSAWNALVHGYKRWCLFPPCTPKFLVKPPINKNWGRLTEASDWFNIMYKRMLLSDWPSEYAMTEAIQKPGETIFVPSGWWHVVLNLTTTVAITQNFCSTINFPIVW 715
            + Y+ DY ++N  +    LY+ D  +     +  + E  +Y  S +  E   +I GD     +R+  +G   S +  H D   + +W+A V G K+W LFPP   + L     N  +  +T A     I Y  +     PSE      IQ+ G+ IF+PSGW H V NL  T++I  N+ +  N   +W
Sbjct:   95 ISYWRDYAEHNCCSPRGCLYLKDWHMRREFPEQNVYETPEYFASDWLNEYWDAIDGDD----YRFVYMGPKGSWTPFHADVFRSYSWSANVCGRKKWLLFPPGQEEHLRDSHGNLPYD-VTSAGLRDPIQYPHLSQCCRPSE-----VIQEAGQVIFIPSGWHHQVYNLEDTISINHNWINGCNVSAMW 273
[Close]
BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. Ensembl Xenopus
Match: JMJD8 (jumonji domain containing 8 [Source:NCBI gene;Acc:100498157])

HSP 1 Score: 50.8322 bits (120), Expect = 1.043e-6
Identity = 38/123 (30.89%), Postives = 57/123 (46.34%), Query Frame = 2 
Query:  329 PPFR------WFVIGSARSGSNIHIDPLGTSAWNALVHGYKRWCLFPP-CTPKFLVKPPINKNWGRLTEASDWFNIMYKRMLLSDWPSEYAMTEAIQKPGETIFVPSGWWHVVLNLTTTVAIT 676
            PPF+       +  G A SG+ +     G   ++ +++G KRW L+PP  TP+F      N N   L+   D +  +         P E    E   +PGE ++ P  WWH  LNL T+V I+
Sbjct:  158 PPFKIPGTSGAYSFGIAGSGTGVPFHWHG-PGYSEVIYGRKRWFLYPPDKTPEF------NPNRTTLSWLLDTYPFL---------PEEDRPIECTIRPGEVLYFPDRWWHATLNLDTSVFIS 264
[Close]
BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. Ensembl Mouse
Match: Jmjd6 (jumonji domain containing 6 [Source:MGI Symbol;Acc:MGI:1858910])

HSP 1 Score: 283.108 bits (723), Expect = 9.076e-93
Identity = 135/240 (56.25%), Postives = 177/240 (73.75%), Query Frame = 2 
Query:  101 YRNQSFRCGDDENDRTVSIKMKYFADYMKNNNDDSPLYVFDGSLDENKKKARLLEDYQVSGYFTEDLFSILGDKIRPPFRWFVIGSARSGSNIHIDPLGTSAWNALVHGYKRWCLFPPCTPKFLVKPPINKNWGRLTEASDWFNIMYKRMLLSDWPSEYAMTEAIQKPGETIFVPSGWWHVVLNLTTTVAITQNFCSTINFPIVWRKTVXXXXXXXXXXXXXXXEIRPDLCEIADEINVN 820
            YRNQ F+CG+D +  +V +KMKY+ +YM++  DDSPLY+FD S  E+ K+ +LLEDY+V  +FT+DLF   G+K RPP+RWFV+G  RSG+ IHIDPLGTSAWNALV G+KRWCLFP  TP+ L+K    +   +  EA  WFN++Y R  L  WP E+   E +QKPGET+FVP GWWHVVLNL TT+AITQNF S+ NFP+VW KTV+ R KLS+ WY+ L +  P+L  +AD +++ 
Sbjct:   94 YRNQKFKCGEDNDGYSVKMKMKYYIEYMESTRDDSPLYIFDSSYGEHPKRRKLLEDYKVPKFFTDDLFQYAGEKRRPPYRWFVMGPPRSGTGIHIDPLGTSAWNALVQGHKRWCLFPTNTPRELIKVTREEGGNQQDEAITWFNVIYPRTQLPTWPPEFKPLEILQKPGETVFVPGGWWHVVLNLDTTIAITQNFASSTNFPVVWHKTVRGRPKLSRKWYRILKQEHPELAVLADAVDLQ 333
[Close]
BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. Ensembl Mouse
Match: Jmjd6 (jumonji domain containing 6 [Source:MGI Symbol;Acc:MGI:1858910])

HSP 1 Score: 277.715 bits (709), Expect = 2.540e-92
Identity = 124/209 (59.33%), Postives = 157/209 (75.12%), Query Frame = 2 
Query:  101 YRNQSFRCGDDENDRTVSIKMKYFADYMKNNNDDSPLYVFDGSLDENKKKARLLEDYQVSGYFTEDLFSILGDKIRPPFRWFVIGSARSGSNIHIDPLGTSAWNALVHGYKRWCLFPPCTPKFLVKPPINKNWGRLTEASDWFNIMYKRMLLSDWPSEYAMTEAIQKPGETIFVPSGWWHVVLNLTTTVAITQNFCSTINFPIVWRKTV 727
            YRNQ F+CG+D +  +V +KMKY+ +YM++  DDSPLY+FD S  E+ K+ +LLEDY+V  +FT+DLF   G+K RPP+RWFV+G  RSG+ IHIDPLGTSAWNALV G+KRWCLFP  TP+ L+K    +   +  EA  WFN++Y R  L  WP E+   E +QKPGET+FVP GWWHVVLNL TT+AITQNF S+ NFP+VW KTV
Sbjct:   46 YRNQKFKCGEDNDGYSVKMKMKYYIEYMESTRDDSPLYIFDSSYGEHPKRRKLLEDYKVPKFFTDDLFQYAGEKRRPPYRWFVMGPPRSGTGIHIDPLGTSAWNALVQGHKRWCLFPTNTPRELIKVTREEGGNQQDEAITWFNVIYPRTQLPTWPPEFKPLEILQKPGETVFVPGGWWHVVLNLDTTIAITQNFASSTNFPVVWHKTV 254
[Close]
BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. Ensembl Mouse
Match: Jmjd6 (jumonji domain containing 6 [Source:MGI Symbol;Acc:MGI:1858910])

HSP 1 Score: 277.33 bits (708), Expect = 7.761e-92
Identity = 124/209 (59.33%), Postives = 157/209 (75.12%), Query Frame = 2 
Query:  101 YRNQSFRCGDDENDRTVSIKMKYFADYMKNNNDDSPLYVFDGSLDENKKKARLLEDYQVSGYFTEDLFSILGDKIRPPFRWFVIGSARSGSNIHIDPLGTSAWNALVHGYKRWCLFPPCTPKFLVKPPINKNWGRLTEASDWFNIMYKRMLLSDWPSEYAMTEAIQKPGETIFVPSGWWHVVLNLTTTVAITQNFCSTINFPIVWRKTV 727
            YRNQ F+CG+D +  +V +KMKY+ +YM++  DDSPLY+FD S  E+ K+ +LLEDY+V  +FT+DLF   G+K RPP+RWFV+G  RSG+ IHIDPLGTSAWNALV G+KRWCLFP  TP+ L+K    +   +  EA  WFN++Y R  L  WP E+   E +QKPGET+FVP GWWHVVLNL TT+AITQNF S+ NFP+VW KTV
Sbjct:   51 YRNQKFKCGEDNDGYSVKMKMKYYIEYMESTRDDSPLYIFDSSYGEHPKRRKLLEDYKVPKFFTDDLFQYAGEKRRPPYRWFVMGPPRSGTGIHIDPLGTSAWNALVQGHKRWCLFPTNTPRELIKVTREEGGNQQDEAITWFNVIYPRTQLPTWPPEFKPLEILQKPGETVFVPGGWWHVVLNLDTTIAITQNFASSTNFPVVWHKTV 259
[Close]
BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. Ensembl Mouse
Match: Jmjd6 (jumonji domain containing 6 [Source:MGI Symbol;Acc:MGI:1858910])

HSP 1 Score: 219.935 bits (559), Expect = 8.037e-70
Identity = 98/177 (55.37%), Postives = 128/177 (72.32%), Query Frame = 2 
Query:  101 YRNQSFRCGDDENDRTVSIKMKYFADYMKNNNDDSPLYVFDGSLDENKKKARLLEDYQVSGYFTEDLFSILGDKIRPPFRWFVIGSARSGSNIHIDPLGTSAWNALVHGYKRWCLFPPCTPKFLVKPPINKNWGRLTEASDWFNIMYKRMLLSDWPSEYAMTEAIQKPGETIFVPSG 631
            YRNQ F+CG+D +  +V +KMKY+ +YM++  DDSPLY+FD S  E+ K+ +LLEDY+V  +FT+DLF   G+K RPP+RWFV+G  RSG+ IHIDPLGTSAWNALV G+KRWCLFP  TP+ L+K    +   +  EA  WFN++Y R  L  WP E+   E +QKPGET+FVP  
Sbjct:   94 YRNQKFKCGEDNDGYSVKMKMKYYIEYMESTRDDSPLYIFDSSYGEHPKRRKLLEDYKVPKFFTDDLFQYAGEKRRPPYRWFVMGPPRSGTGIHIDPLGTSAWNALVQGHKRWCLFPTNTPRELIKVTREEGGNQQDEAITWFNVIYPRTQLPTWPPEFKPLEILQKPGETVFVPGS 270
[Close]
BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. Ensembl Mouse
Match: Jmjd6 (jumonji domain containing 6 [Source:MGI Symbol;Acc:MGI:1858910])

HSP 1 Score: 114.39 bits (285), Expect = 6.213e-30
Identity = 52/94 (55.32%), Postives = 65/94 (69.15%), Query Frame = 2 
Query:  446 FPPCTPKFLVKPPINKNWGRLTEASDWFNIMYKRMLLSDWPSEYAMTEAIQKPGETIFVPSGWWHVVLNLTTTVAITQNFCSTINFPIVWRKTV 727
            FP  TP+ L+K    +   +  EA  WFN++Y R  L  WP E+   E +QKPGET+FVP GWWHVVLNL TT+AITQNF S+ NFP+VW KT+
Sbjct:    2 FPTNTPRELIKVTREEGGNQQDEAITWFNVIYPRTQLPTWPPEFKPLEILQKPGETVFVPGGWWHVVLNLDTTIAITQNFASSTNFPVVWHKTI 95
[Close]
BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. UniProt/SwissProt
Match: sp|Q6PFM0|JMJD6_DANRE (Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 OS=Danio rerio OX=7955 GN=jmjd6 PE=2 SV=2)

HSP 1 Score: 290.812 bits (743), Expect = 5.423e-95
Identity = 137/240 (57.08%), Postives = 181/240 (75.42%), Query Frame = 2 
Query:  101 YRNQSFRCGDDENDRTVSIKMKYFADYMKNNNDDSPLYVFDGSLDENKKKARLLEDYQVSGYFTEDLFSILGDKIRPPFRWFVIGSARSGSNIHIDPLGTSAWNALVHGYKRWCLFPPCTPKFLVKPPINKNWGRLTEASDWFNIMYKRMLLSDWPSEYAMTEAIQKPGETIFVPSGWWHVVLNLTTTVAITQNFCSTINFPIVWRKTVXXXXXXXXXXXXXXXEIRPDLCEIADEINVN 820
            YRNQ F+CG+D +  +V +KMKY+ +Y+++ +DDSPLY+FD S  E+ K+ +LLEDYQV  +F +DLF   G+K RPP+RWFV+G ARSG+ IHIDPLGTSAWNALV G+KRWCLFP  TP+ L+K   ++   +  EA  WFN++Y R   S WP E+   E +Q+PGET+FVP GWWHVVLNL TT+A+TQNF ST NFPIVW KTV+ R KLS+ WY+ L + RPD+  IAD++++ 
Sbjct:   94 YRNQKFKCGEDNDGYSVKMKMKYYVEYLESTHDDSPLYIFDSSFGEHAKRRKLLEDYQVPLFFRDDLFQFAGEKRRPPYRWFVMGPARSGTGIHIDPLGTSAWNALVQGHKRWCLFPTHTPRELIKVTRDEGGNQQDEAITWFNVIYPRTQQSTWPDEFRPLEILQRPGETVFVPGGWWHVVLNLDTTIAVTQNFASTTNFPIVWHKTVRGRPKLSRKWYRILKQERPDIAAIADKVDLQ 333
[Close]
BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. UniProt/SwissProt
Match: sp|Q6GND3|JMD6A_XENLA (Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6-A OS=Xenopus laevis OX=8355 GN=jmjd6-a PE=2 SV=1)

HSP 1 Score: 287.345 bits (734), Expect = 1.511e-93
Identity = 136/240 (56.67%), Postives = 177/240 (73.75%), Query Frame = 2 
Query:  101 YRNQSFRCGDDENDRTVSIKMKYFADYMKNNNDDSPLYVFDGSLDENKKKARLLEDYQVSGYFTEDLFSILGDKIRPPFRWFVIGSARSGSNIHIDPLGTSAWNALVHGYKRWCLFPPCTPKFLVKPPINKNWGRLTEASDWFNIMYKRMLLSDWPSEYAMTEAIQKPGETIFVPSGWWHVVLNLTTTVAITQNFCSTINFPIVWRKTVXXXXXXXXXXXXXXXEIRPDLCEIADEINVN 820
            YRNQ F+CG+D +  +V +KMKY+ DYM+   DDSPLY+FD S  E+ K+ +LLEDY+V  YF +DLF   G+K RPP+RWFV+G ARSG+ IHIDPLGTSAWN+LVHG+KRWCLFP  TP+ L+K   ++   +  EA  WFN++Y R  L  WP E+   E +QKPGET+FVP GWWHVVLNL T +A+TQNF S  NFP+VW KTV+ R KLS+ WY+ L + RP+L  +AD +++ 
Sbjct:   94 YRNQKFKCGEDNDGYSVKMKMKYYIDYMEGTRDDSPLYIFDSSYGEHPKRKKLLEDYEVPKYFRDDLFQFAGEKRRPPYRWFVMGPARSGTGIHIDPLGTSAWNSLVHGHKRWCLFPTNTPRELIKVTRDEGGNQQDEAITWFNVIYPRTQLPSWPPEFKPLEILQKPGETVFVPGGWWHVVLNLDTAIAVTQNFASCSNFPVVWHKTVRGRPKLSRKWYRILKQERPELAALADTVDLQ 333
[Close]
BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. UniProt/SwissProt
Match: sp|Q5R6G2|JMJD6_PONAB (Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 OS=Pongo abelii OX=9601 GN=JMJD6 PE=2 SV=1)

HSP 1 Score: 284.648 bits (727), Expect = 1.408e-92
Identity = 135/240 (56.25%), Postives = 178/240 (74.17%), Query Frame = 2 
Query:  101 YRNQSFRCGDDENDRTVSIKMKYFADYMKNNNDDSPLYVFDGSLDENKKKARLLEDYQVSGYFTEDLFSILGDKIRPPFRWFVIGSARSGSNIHIDPLGTSAWNALVHGYKRWCLFPPCTPKFLVKPPINKNWGRLTEASDWFNIMYKRMLLSDWPSEYAMTEAIQKPGETIFVPSGWWHVVLNLTTTVAITQNFCSTINFPIVWRKTVXXXXXXXXXXXXXXXEIRPDLCEIADEINVN 820
            YRNQ F+CG+D +  +V +KMKY+ +YM++  DDSPLY+FD S  E+ K+ +LLEDY+V  +FT+DLF   G+K RPP+RWFV+G  RSG+ IHIDPLGTSAWNALV G+KRWCLFP  TP+ L+K   ++   +  EA  WFN++Y R  L  WP E+   E +QKPGET+FVP GWWHVVLNL TT+AITQNF S+ NFP+VW KTV+ R KLS+ WY+ L +  P+L  +AD +++ 
Sbjct:   94 YRNQKFKCGEDNDGYSVKMKMKYYIEYMESTRDDSPLYIFDSSYGEHPKRRKLLEDYKVPKFFTDDLFQYAGEKRRPPYRWFVMGPPRSGTGIHIDPLGTSAWNALVQGHKRWCLFPTSTPRELIKVTRDEGGNQQDEAITWFNVIYPRTQLPTWPPEFKPLEILQKPGETVFVPGGWWHVVLNLDTTIAITQNFASSTNFPVVWHKTVRGRPKLSRKWYRILKQEHPELAVLADSVDLQ 333
[Close]
BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. UniProt/SwissProt
Match: sp|Q6NYC1|JMJD6_HUMAN (Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 OS=Homo sapiens OX=9606 GN=JMJD6 PE=1 SV=1)

HSP 1 Score: 284.648 bits (727), Expect = 1.408e-92
Identity = 135/240 (56.25%), Postives = 178/240 (74.17%), Query Frame = 2 
Query:  101 YRNQSFRCGDDENDRTVSIKMKYFADYMKNNNDDSPLYVFDGSLDENKKKARLLEDYQVSGYFTEDLFSILGDKIRPPFRWFVIGSARSGSNIHIDPLGTSAWNALVHGYKRWCLFPPCTPKFLVKPPINKNWGRLTEASDWFNIMYKRMLLSDWPSEYAMTEAIQKPGETIFVPSGWWHVVLNLTTTVAITQNFCSTINFPIVWRKTVXXXXXXXXXXXXXXXEIRPDLCEIADEINVN 820
            YRNQ F+CG+D +  +V +KMKY+ +YM++  DDSPLY+FD S  E+ K+ +LLEDY+V  +FT+DLF   G+K RPP+RWFV+G  RSG+ IHIDPLGTSAWNALV G+KRWCLFP  TP+ L+K   ++   +  EA  WFN++Y R  L  WP E+   E +QKPGET+FVP GWWHVVLNL TT+AITQNF S+ NFP+VW KTV+ R KLS+ WY+ L +  P+L  +AD +++ 
Sbjct:   94 YRNQKFKCGEDNDGYSVKMKMKYYIEYMESTRDDSPLYIFDSSYGEHPKRRKLLEDYKVPKFFTDDLFQYAGEKRRPPYRWFVMGPPRSGTGIHIDPLGTSAWNALVQGHKRWCLFPTSTPRELIKVTRDEGGNQQDEAITWFNVIYPRTQLPTWPPEFKPLEILQKPGETVFVPGGWWHVVLNLDTTIAITQNFASSTNFPVVWHKTVRGRPKLSRKWYRILKQEHPELAVLADSVDLQ 333
[Close]
BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. UniProt/SwissProt
Match: sp|Q5ZMK5|JMJD6_CHICK (Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 OS=Gallus gallus OX=9031 GN=JMJD6 PE=2 SV=1)

HSP 1 Score: 284.648 bits (727), Expect = 2.208e-92
Identity = 136/240 (56.67%), Postives = 175/240 (72.92%), Query Frame = 2 
Query:  101 YRNQSFRCGDDENDRTVSIKMKYFADYMKNNNDDSPLYVFDGSLDENKKKARLLEDYQVSGYFTEDLFSILGDKIRPPFRWFVIGSARSGSNIHIDPLGTSAWNALVHGYKRWCLFPPCTPKFLVKPPINKNWGRLTEASDWFNIMYKRMLLSDWPSEYAMTEAIQKPGETIFVPSGWWHVVLNLTTTVAITQNFCSTINFPIVWRKTVXXXXXXXXXXXXXXXEIRPDLCEIADEINVN 820
            YRNQ F+CG+D +  +V +KMKY+ +YM+   DDSPLY+FD S  E+ K+ +LLEDY+V  +FT+DLF   G+K RPP+RWFV+G  RSG+ IHIDPLGTSAWNALV G+KRWCLFP  TP+ L+K    +   +  EA  WFN++Y R  L  WP E+   E +QKPGET+FVP GWWHVVLNL TT+AITQNF S  NFP+VW KTV+ R KLS+ WY+ L +  PDL  +AD +++ 
Sbjct:   94 YRNQKFKCGEDNDGYSVKMKMKYYIEYMETTRDDSPLYIFDSSYGEHPKRRKLLEDYKVPKFFTDDLFQYAGEKRRPPYRWFVMGPPRSGTGIHIDPLGTSAWNALVQGHKRWCLFPTSTPRELIKVAREEGGNQQDEAITWFNVIYPRTQLPTWPPEFKPLEILQKPGETVFVPGGWWHVVLNLDTTIAITQNFASCTNFPVVWHKTVRGRPKLSRKWYRILKQEHPDLAALADSVDLQ 333
[Close]
BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. TrEMBL
Match: A0A4E0RA73 (Bifunctional arginine demethylase and lysyl-hydroxylase PSR OS=Fasciola hepatica OX=6192 GN=D915_010411 PE=4 SV=1)

HSP 1 Score: 300.442 bits (768), Expect = 5.487e-96
Identity = 146/239 (61.09%), Postives = 178/239 (74.48%), Query Frame = 2 
Query:  101 YRNQSFRCGDDENDRTVSIKMKYFADYMKNNNDDSPLYVFDGSLDENKKKARLLEDYQVSGYFTEDLFSILGDKIRPPFRWFVIGSARSGSNIHIDPLGTSAWNALVHGYKRWCLFPPCTPKFLVKPPINKNWGRLTEASDWFNIMYKRMLLSDWPSEYAMTEAIQKPGETIFVPSGWWHVVLNLTTTVAITQNFCSTINFPIVWRKTVXXXXXXXXXXXXXXXEIRPDLCEIADEINV 817
            YRNQ F+CG+D++  +V IKMKYF +YM++N DDSPLY+FD +  E+ K+ +LLEDY VS YF EDLFS  G+K RPP+RWF++GSARSG+ IHIDPLGTSAWNALV GYKRWCLFPP TPK LVKP          EA  WF+ +Y R  + DWP +Y   E +Q PGETIFVP GWWHVVLNLT TVA+TQNFCS+ NFPIVW KT + R + S++W   L   RPDL + AD+I+ 
Sbjct:  100 YRNQRFKCGEDDSGYSVKIKMKYFVNYMRDNIDDSPLYIFDANFGEHPKRKKLLEDYSVSKYFPEDLFSYGGEKRRPPYRWFLMGSARSGTGIHIDPLGTSAWNALVKGYKRWCLFPPQTPKELVKPQPTDGGKNKDEAIAWFDHVYPRTRMPDWPQQYRPLEVLQHPGETIFVPGGWWHVVLNLTDTVAVTQNFCSSKNFPIVWHKTARARPRFSRIWMDALRINRPDLAKTADDIDT 338
[Close]
BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. TrEMBL
Match: A0A504YFI4 (Bifunctional arginine demethylase and lysyl-hydroxylase PSR OS=Fasciola gigantica OX=46835 GN=FGIG_06408 PE=4 SV=1)

HSP 1 Score: 300.442 bits (768), Expect = 3.088e-95
Identity = 146/239 (61.09%), Postives = 178/239 (74.48%), Query Frame = 2 
Query:  101 YRNQSFRCGDDENDRTVSIKMKYFADYMKNNNDDSPLYVFDGSLDENKKKARLLEDYQVSGYFTEDLFSILGDKIRPPFRWFVIGSARSGSNIHIDPLGTSAWNALVHGYKRWCLFPPCTPKFLVKPPINKNWGRLTEASDWFNIMYKRMLLSDWPSEYAMTEAIQKPGETIFVPSGWWHVVLNLTTTVAITQNFCSTINFPIVWRKTVXXXXXXXXXXXXXXXEIRPDLCEIADEINV 817
            YRNQ F+CG+D++  +V IKMKYF +YM++N DDSPLY+FD +  E+ K+ +LLEDY VS YF EDLFS  G+K RPP+RWF++GSARSG+ IHIDPLGTSAWNALV GYKRWCLFPP TPK LVKP          EA  WF+ +Y R  + DWP +Y   E +Q PGETIFVP GWWHVVLNLT TVA+TQNFCS+ NFPIVW KT + R + S++W   L   RPDL + AD+I+ 
Sbjct:  100 YRNQRFKCGEDDSGYSVKIKMKYFVNYMRDNIDDSPLYIFDANFGEHPKRKKLLEDYSVSKYFPEDLFSYGGEKRRPPYRWFLMGSARSGTGIHIDPLGTSAWNALVKGYKRWCLFPPQTPKELVKPQPTDGGKNKDEAIAWFDHVYPRTRMPDWPQQYRPLEVLQHPGETIFVPGGWWHVVLNLTDTVAVTQNFCSSKNFPIVWHKTARARPRFSRIWMDALRINRPDLAKTADDIDT 338
[Close]
BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. TrEMBL
Match: A0A267GDN6 (JmjC domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig015404g1 PE=4 SV=1)

HSP 1 Score: 294.664 bits (753), Expect = 4.058e-94
Identity = 137/240 (57.08%), Postives = 180/240 (75.00%), Query Frame = 2 
Query:  101 YRNQSFRCGDDENDRTVSIKMKYFADYMKNNNDDSPLYVFDGSLDENKKKARLLEDYQVSGYFTEDLFSILGDKIRPPFRWFVIGSARSGSNIHIDPLGTSAWNALVHGYKRWCLFPPCTPKFLVKPPINKNWGRLTEASDWFNIMYKRMLLSDWPSEYAMTEAIQKPGETIFVPSGWWHVVLNLTTTVAITQNFCSTINFPIVWRKTVXXXXXXXXXXXXXXXEIRPDLCEIADEINVN 820
            YRNQ F+CG+D++  +V IKMKYF  YM+ N+DDSPLY+FDG+  E++KK +LLEDY+VS  F EDLFS+ G++ RPP+RWFV+G ARSG+ IHIDPLGTSAWNALV G+KRWCLFP   PK LVKP   +   +  EA+ WF+ +Y R   +DWP  +   E +Q+PGET+FVP GWWHVVLNL  TVA+TQNFCS++NFP VW KT + R K+++    +L + RPDL  +A+ I+ +
Sbjct:   97 YRNQRFKCGEDDDGYSVRIKMKYFTQYMRANSDDSPLYIFDGNFGEHRKKRKLLEDYRVSHLFPEDLFSLAGERRRPPYRWFVMGPARSGTGIHIDPLGTSAWNALVRGHKRWCLFPIDAPKDLVKPAGIEASKQKGEAAAWFSCVYPRTQQADWPERWRPLEILQRPGETVFVPGGWWHVVLNLDDTVAVTQNFCSSVNFPTVWHKTKRGRPKMARKMLAELKQTRPDLAAVAESIDTS 336
[Close]
BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. TrEMBL
Match: A0A443SVG2 (Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6-A-like protein OS=Leptotrombidium deliense OX=299467 GN=B4U80_07435 PE=4 SV=1)

HSP 1 Score: 294.664 bits (753), Expect = 4.284e-94
Identity = 141/240 (58.75%), Postives = 179/240 (74.58%), Query Frame = 2 
Query:  101 YRNQSFRCGDDENDRTVSIKMKYFADYMKNNNDDSPLYVFDGSLDENKKKARLLEDYQVSGYFTEDLFSILGDKIRPPFRWFVIGSARSGSNIHIDPLGTSAWNALVHGYKRWCLFPPCTPKFLVKPPINKNWGRLTEASDWFNIMYKRMLLSDWPSEYAMTEAIQKPGETIFVPSGWWHVVLNLTTTVAITQNFCSTINFPIVWRKTVXXXXXXXXXXXXXXXEIRPDLCEIADEINVN 820
            YRNQ F+CG+D    +V +KMKYF  YM+NN+DDSPLY+FD S  E+ +K+RLLEDY++  YF +DLF  +G++ RPP+RWFV+G  RSG+ IHIDPLGTSAWNAL+ GYKRWCLFP  TPK L+K  + +   +  EA  WFN +Y R   ++WPSE+   E IQKPGET+FVP GWWHVV+NLT T+A+TQNFCS  NFP+VW KT   R KLS+ WY+ L E  PDL  IAD +++N
Sbjct:  109 YRNQKFKCGEDNEGYSVKLKMKYFVYYMENNDDDSPLYIFDSSFGEHPRKSRLLEDYEIPIYFRDDLFKYVGEEKRPPYRWFVMGPPRSGTGIHIDPLGTSAWNALIQGYKRWCLFPTNTPKHLIKVSMVEGGKQCDEAISWFNTIYPRTKSAEWPSEFKPLEIIQKPGETVFVPGGWWHVVVNLTNTIAVTQNFCSLTNFPVVWHKTFHGRPKLSQKWYRILKEQLPDLATIADHVDLN 348
[Close]
BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. TrEMBL
Match: V3ZV57 (JmjC domain-containing protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_117140 PE=4 SV=1)

HSP 1 Score: 294.664 bits (753), Expect = 5.794e-94
Identity = 145/239 (60.67%), Postives = 181/239 (75.73%), Query Frame = 2 
Query:  101 YRNQSFRCGDDENDRTVSIKMKYFADYMKNNNDDSPLYVFDGSLDENKKKARLLEDYQVSGYFTEDLFSILGDKIRPPFRWFVIGSARSGSNIHIDPLGTSAWNALVHGYKRWCLFPPCTPKFLVKPPINKNWGRLTEASDWFNIMYKRMLLSDWPSEYAMTEAIQKPGETIFVPSGWWHVVLNLTTTVAITQNFCSTINFPIVWRKTVXXXXXXXXXXXXXXXEIRPDLCEIADEINV 817
            YRNQ F+CGDD++  +V IKMKYF DYMK+NNDDSPLY+FD S  E+ KK +LLEDY++  YF +DLF   G++ RPP+RWFV+G ARSG+ IHIDPLGTSAWNALV GYKRWCL P  TP+ LVK    +   +  EA  WF+I+Y +   S WP +Y   E +QKPGET+FVPSGWWHVV+NL  T+A+TQNF S  NFPIVW KTV+ R KLSK WYK L ++RP++ E+AD++ V
Sbjct:   96 YRNQKFKCGDDDDGYSVKIKMKYFVDYMKHNNDDSPLYIFD-SYGEHAKKKKLLEDYEIPKYFQDDLFRYAGEEKRPPYRWFVMGPARSGTGIHIDPLGTSAWNALVSGYKRWCLLPTETPRELVKLKGEEGGKQQDEAVTWFDIVYPKTQESSWPQQYKPLEILQKPGETVFVPSGWWHVVVNLEDTIAVTQNFASVTNFPIVWHKTVRGRPKLSKKWYKILQKVRPEIAEVADQVKV 333
[Close]
BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. Ensembl Cavefish
Match: jmjd6 (jumonji domain containing 6, arginine demethylase and lysine hydroxylase [Source:NCBI gene;Acc:103029547])

HSP 1 Score: 285.419 bits (729), Expect = 7.651e-94
Identity = 135/240 (56.25%), Postives = 179/240 (74.58%), Query Frame = 2 
Query:  101 YRNQSFRCGDDENDRTVSIKMKYFADYMKNNNDDSPLYVFDGSLDENKKKARLLEDYQVSGYFTEDLFSILGDKIRPPFRWFVIGSARSGSNIHIDPLGTSAWNALVHGYKRWCLFPPCTPKFLVKPPINKNWGRLTEASDWFNIMYKRMLLSDWPSEYAMTEAIQKPGETIFVPSGWWHVVLNLTTTVAITQNFCSTINFPIVWRKTVXXXXXXXXXXXXXXXEIRPDLCEIADEINVN 820
            YRNQ F+CG+D +  +V +KMKY+ +YM+++ DDSPLY+FD S  E+ K+ +LLEDYQV  +F +DLF   G+K RPP+RWFV+G ARSG+ IHIDPLGTSAWNALV G+KRWCLFP  TP+ L+K   ++   +  EA  WF+++Y R     WP+E+   E +Q PGET+FVP GWWHVVLNL T +A+TQNF ST NFPIVW KTV+ R KLS+ WY+ L + RPDL  +AD++++ 
Sbjct:   94 YRNQKFKCGEDNDGYSVKMKMKYYVEYMESSRDDSPLYIFDSSYGEHAKRRKLLEDYQVPVFFRDDLFQFAGEKRRPPYRWFVMGPARSGTGIHIDPLGTSAWNALVQGHKRWCLFPTHTPRELIKVTRDEGGNQQDEAITWFSVIYPRTQQPTWPAEFRPLEILQHPGETVFVPGGWWHVVLNLDTAIAVTQNFASTTNFPIVWHKTVRGRPKLSRKWYRILKQERPDLASLADKVDLQ 333
[Close]
BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. Ensembl Cavefish
Match: jmjd4 (jumonji domain containing 4 [Source:NCBI gene;Acc:767690])

HSP 1 Score: 70.0922 bits (170), Expect = 4.003e-13
Identity = 52/190 (27.37%), Postives = 89/190 (46.84%), Query Frame = 2 
Query:  161 MKYFADYMKNNNDDSP---LYVFDGSLDENKKKARLLEDYQVSGYFTEDLFSILGDKIR-PPFRWFVIGSARSGSNIHIDPLGTSAWNALVHGYKRWCLFPPCTPKFLVKPPINKNWGRLTEASDWFNIMYKRMLLSDWPSEYAMTEAIQKPGETIFVPSGWWHVVLNLTTTVAITQNFCSTINFPIVWR 718
            ++Y+ +Y++N +  SP   LY+ D  +   ++       Y+   YF+ D  +   D I    +R+  +G   S +  H D   + +W+A + G K+W L+PP   +FL     N  +     A      +  +     +       E IQ+ GE IFVPSGW H V NL  T++I  N+ +  N  ++W+
Sbjct:  115 IQYWREYIQNGHS-SPRGCLYLKDWHM---QRMFPEHNTYKTPIYFSSDWLNEYWDTIEVDDYRFVYMGPKGSWTPFHADVFRSYSWSANICGRKKWLLYPPGQEEFLRDCHGNLAYDVTAAA------LQDKGQFPHFQEACQPLEIIQEAGEIIFVPSGWHHQVYNLEDTISINHNWLNGCNLDVMWQ 294
[Close]
BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. Ensembl Sea Lamprey
Match: jmjd6 (jumonji domain containing 6, arginine demethylase and lysine hydroxylase [Source:NCBI gene;Acc:266962])

HSP 1 Score: 280.026 bits (715), Expect = 2.081e-92
Identity = 134/240 (55.83%), Postives = 174/240 (72.50%), Query Frame = 2 
Query:  101 YRNQSFRCGDDENDRTVSIKMKYFADYMKNNNDDSPLYVFDGSLDENKKKARLLEDYQVSGYFTEDLFSILGDKIRPPFRWFVIGSARSGSNIHIDPLGTSAWNALVHGYKRWCLFPPCTPKFLVKPPINKNWGRLTEASDWFNIMYKRMLLSDWPSEYAMTEAIQKPGETIFVPSGWWHVVLNLTTTVAITQNFCSTINFPIVWRKTVXXXXXXXXXXXXXXXEIRPDLCEIADEINVN 820
            YRNQ F+CG+D +  +V +KMKY+ DY++  NDDSPLY+FD S  ++ KK +LLEDY++  YF +DLF   G+K RPP+RWFV+G ARSG+ IHIDPLGTSAWNALV G+KRWCLFP  TP+ L+K    +   +  EA  WF+++Y R     WP E+   E +QKPGET+FVP GWWHVVLNL  T+A+TQNF S  NFP+VW KTV+ R KLS+ WY+ L +  PDL  +AD +N+ 
Sbjct:   96 YRNQKFKCGEDNDGYSVKLKMKYYIDYVETTNDDSPLYIFDSSFGDHAKKGKLLEDYEIPVYFKDDLFKYAGEKRRPPYRWFVMGPARSGTGIHIDPLGTSAWNALVKGHKRWCLFPTNTPRELIKVAREEGGIQQDEAITWFSVIYPRTQEPSWPPEFRPLEILQKPGETVFVPGGWWHVVLNLENTIAVTQNFASVTNFPVVWHKTVRGRPKLSRKWYRILKQEFPDLAAVADSVNLQ 335
[Close]
BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. Ensembl Sea Lamprey
Match: jmjd4 (jumonji domain containing 4 [Source:NCBI gene;Acc:767690])

HSP 1 Score: 62.7734 bits (151), Expect = 2.393e-11
Identity = 53/197 (26.90%), Postives = 84/197 (42.64%), Query Frame = 2 
Query:  161 MKYFADYMKNNNDDSP---LYVFDGSLDENKKKARLLEDYQVSGYFTEDLFSILGDKIRPP-FRWFVIGSARSGSNIHIDPLGTSAWNALVHGYKRWCLFPPCTPKFLVKPPINKNWGRLTEASDWFNIMYKRMLLSDWPSEYAM--------TEAIQKPGETIFVPSGWWHVVLNLTTTVAITQNFCSTINFPIVW 715
            + Y+ + M  ++  SP   LY+ D  +    K+    + Y     F+ D  +   D +    +R+  +G   S +  H D   + +W+A V G K W L+PP   + L       + G         N+ Y       WP +            E IQ+ GE IF+PSGW H V NL  T++I  N+ +  N  +VW
Sbjct:  101 LSYWQETMSQDHSSSPRPCLYLKDWHM---CKEFPDYDAYSTPECFSSDWLNEYWDAVHSDDYRFVYMGPRGSWTPFHADVFRSYSWSANVCGRKLWLLYPPGQEEAL-----RDHLG---------NLPYDVTAPDPWPQDAPAKKQRGQKPMEVIQEAGEIIFIPSGWHHQVHNLEDTISINHNWLNGCNIDLVW 280
[Close]
BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. Ensembl Nematostella
Match: EDO41023 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S5J7])

HSP 1 Score: 263.077 bits (671), Expect = 2.377e-85
Identity = 122/240 (50.83%), Postives = 176/240 (73.33%), Query Frame = 2 
Query:  101 YRNQSFRCGDDENDRTVSIKMKYFADYMKNNNDDSPLYVFDGSLDENKKKARLLEDYQVSGYFTEDLFSILGDKIRPPFRWFVIGSARSGSNIHIDPLGTSAWNALVHGYKRWCLFPPCTPKFLVKPPINKNWGRLTEASDWFNIMYKRMLLSDWPSEYAMTEAIQKPGETIFVPSGWWHVVLNLTTTVAITQNFCSTINFPIVWRKTVXXXXXXXXXXXXXXXEIRPDLCEIADEINVN 820
            +R+Q F+ G+D++   V +KMKY+++Y+++N DDSPLY+FD S  E+  K +LLE+Y+V  +F +DLF   G+K RPP+RWFV+G ARSG+ IHIDPLGTSAWN++V G+KRW +FP   P+ ++K P ++   +  EA  WF  +Y +  LS WP EY   E +Q PGET+FVP GWWHVV+NL   +A+TQNF S +NFP+VW KTV+ R KLSK W K+L + RP++ ++A ++N++
Sbjct:   94 FRHQKFKVGEDDDGYAVKMKMKYYSEYIQHNKDDSPLYIFDSSFGEHPVKKKLLEEYEVPRFFADDLFRYAGEKRRPPYRWFVMGPARSGTGIHIDPLGTSAWNSVVSGHKRWAMFPTFVPQEMLKVPSSEGGKQRDEAITWFTHVYPKTQLSSWPEEYKPVEVLQGPGETVFVPGGWWHVVVNLDAAIAVTQNFSSPVNFPVVWHKTVRGRPKLSKKWLKRLKKQRPEIYKMAQQVNLD 333
[Close]
BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. Ensembl Nematostella
Match: EDO30657 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T061])

HSP 1 Score: 77.0258 bits (188), Expect = 1.065e-15
Identity = 68/254 (26.77%), Postives = 101/254 (39.76%), Query Frame = 2 
Query:  137 NDRTVSIKMKYFADYMKNNN--DDSPLYVFDGSLDENKKKARLLEDYQVSGYFTE--DLFSILGDKIRPPFRWFVIGSARSGSNIHIDPLGTSAWNALVHGYKRWCLFPPCTPKFLVKPPINKNWGR-----LTEASDWFN--------------------------------IMYKRMLLSDWPSEYAM-TEAIQKPGETIF---------------------------VPSGWWHVVLNLTTTVAITQNFCS 691
             DR   + ++ F  Y K     D +P  VF    D  +    LL+DY+V  YF+E  D  + + D +R  +RW ++    SGS  H DP  T+ W AL  G K W L+PP        P +  N+ +     + +A +W+                                   Y+ M++   PS Y +  E I    E ++                           +PSGW+H VLNL  TVA+TQNFC+
Sbjct:  128 GDREEMVPVRVFNRYTKTRAKLDAAPWMVF--MPDVFEMYPELLKDYKVPDYFSEEDDFMTGVPDDLRMDWRWIIMAPRGSGSGWHCDPANTTGWLALATGAKLWGLYPPEQAHI---PGVKNNYYQKRDYNMDDAYNWWIHTRPSLEHDHRVHSEFSSRVHRVHTEFIPGTLYTYRNMIIVYIPSSYRVHNECIPSTSEVLYTYRNMIIAYIEYDLPRECIQQAGDIVYIPSGWYHAVLNLDHTVAVTQNFCN 376
[Close]
BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. Ensembl Nematostella
Match: EDO45976 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRA5])

HSP 1 Score: 72.7886 bits (177), Expect = 3.255e-14
Identity = 41/133 (30.83%), Postives = 64/133 (48.12%), Query Frame = 2 
Query:  296 DLFSILGDKIRPPFRWFVIGSARSGSNIHIDPLGTSAWNALVHGYKRWCLFPPCT--PKFLVKPPINKNWGRLTEASDWFNIMYKRMLLSDWPSEYAMTEAIQKPGETIFVPSGWWHVVLNLTTTVAITQNFC 688
            D    + + I+P      +   RSG +  ++    S W+ALV G+KRW L+PP    P  +V         + +E   W+     R+     PSE      +QKPGE +++PSGWW   +NL  T+ + + FC
Sbjct:  301 DYMQFVDEDIKPAQLSLQMAPQRSGYHWRVEQYNGSLWSALVRGHKRWGLYPPSVYFPPGVVHNNHRAQDSQSSEPFTWWAHTQPRLRADRRPSE-----CVQKPGEILYIPSGWWWSHINLEDTITLQRWFC 428
[Close]
BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. Ensembl Nematostella
Match: EDO26853 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7TAW4])

HSP 1 Score: 60.4622 bits (145), Expect = 1.385e-11
Identity = 37/104 (35.58%), Postives = 53/104 (50.96%), Query Frame = 2 
Query:  155 IKMKYFADYMKNNN--DDSPLYVFDGSLDENKKKARLLEDYQVSGYFTE--DLFSILGDKIRPPFRWFVIGSARSGSNIHIDPLGTSAWNALVHGYKRWCLFPP 454
            + ++ F  Y K     D +P  VF    D  +    LL+DY+V  YF+E  D  + + D +R  +RW ++    SGS  H DP  T+ W AL  G K W L+PP
Sbjct:    2 VPVRVFNRYTKTRAKLDAAPWMVF--MPDVFEMYPELLKDYKVPDYFSEEDDFMTGVPDDLRMDWRWIIMAPRGSGSGWHCDPANTTGWLALATGAKLWGLYPP 103
[Close]
BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. Ensembl Nematostella
Match: EDO48393 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RJK6])

HSP 1 Score: 61.2326 bits (147), Expect = 1.931e-10
Identity = 50/194 (25.77%), Postives = 88/194 (45.36%), Query Frame = 2 
Query:  170 FADYMKNN--NDDSPLYVFDGSLDENKKKARLLEDYQVSGYFTEDLF--SILGDKIRPPFRWFVIGSARSGSNIHIDPLGTSAWNALVHGYKRWC---------LFPPCTPKFLVKPPINKNWGRLTEASDWFNIMYKRMLLSDWPSEYAMTEAIQKPGETIFVPSGWWHVVLNLTTTVAITQNFCSTINFPIV 712
             AD++ +N  + + PLY+FD SL  +     L ++  +  YF+ D    ++ G   +  +    I  A   S++H+D  G++ W AL  G K+W          L+P C  + L    I+ +       + +F ++          ++    + I +PGE +FVP G  H V NL  ++A++ NF    N   V
Sbjct:  330 LADFIDSNMRSGNEPLYLFDWSLPTHA--PHLAKELTIPRYFSGDFLQRTVDGSLYKDTWPSLFIAPAGLVSDLHVDGFGSNFWMALFQGRKKWTFFNKSDLPLLYPHCDDQSL---NISFDVNLANPDTKYFPLL----------AQTTPRQCILEPGELLFVPHGSPHFVENLEDSLAVSANFVDLSNHSAV 508
[Close]
BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. Ensembl Medaka
Match: jmjd6 (jumonji domain containing 6, arginine demethylase and lysine hydroxylase [Source:NCBI gene;Acc:101161943])

HSP 1 Score: 284.263 bits (726), Expect = 2.598e-93
Identity = 134/240 (55.83%), Postives = 178/240 (74.17%), Query Frame = 2 
Query:  101 YRNQSFRCGDDENDRTVSIKMKYFADYMKNNNDDSPLYVFDGSLDENKKKARLLEDYQVSGYFTEDLFSILGDKIRPPFRWFVIGSARSGSNIHIDPLGTSAWNALVHGYKRWCLFPPCTPKFLVKPPINKNWGRLTEASDWFNIMYKRMLLSDWPSEYAMTEAIQKPGETIFVPSGWWHVVLNLTTTVAITQNFCSTINFPIVWRKTVXXXXXXXXXXXXXXXEIRPDLCEIADEINVN 820
            YRNQ F+CG+D +  +V +KMKY+ +Y+++  DDSPLY+FD S  E+ K+ +LLEDY+V  +F +DLF   G+K RPP+RWFV+G ARSG+ IHIDPLGTSAWNALV G+KRWCLFP  TP+ L+K    +   +  EA  WF+++Y R     WP E+   E +Q+PGET+FVP GWWHVVLNL TT+A+TQNF ST NFPIVW KTV+ R KLS+ WY+ L + RPDL  +AD++++ 
Sbjct:   94 YRNQKFKCGEDNDGYSVKMKMKYYMEYLESTKDDSPLYIFDSSYGEHAKRQKLLEDYEVPVFFRDDLFQFAGEKRRPPYRWFVMGPARSGTGIHIDPLGTSAWNALVQGHKRWCLFPTNTPRELIKVTREEGGNQQDEAITWFSVVYPRSQQPTWPQEFRPLEILQRPGETVFVPGGWWHVVLNLDTTIAVTQNFASTTNFPIVWHKTVRGRPKLSRKWYRVLKQERPDLAALADKVDLQ 333
[Close]
BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. Ensembl Medaka
Match: jmjd4 (jumonji domain containing 4 [Source:NCBI gene;Acc:101156282])

HSP 1 Score: 67.3958 bits (163), Expect = 4.379e-12
Identity = 51/189 (26.98%), Postives = 90/189 (47.62%), Query Frame = 2 
Query:  161 MKYFADYMKNNNDDSP--LYVFDGSLDENKKKARLLEDYQVSGYFTEDLFSILGDKIR-PPFRWFVIGSARSGSNIHIDPLGTSAWNALVHGYKRWCLFPPCTPKFLVKPPINKNWGRLTEASDWFNIMYKRMLLSDWPSEYAMTEAIQKPGETIFVPSGWWHVVLNLTTTVAITQNFCSTINFPIVWR 718
            + Y+ +Y++N +      LY+ D  +  +  +  +   Y    +F+ D  +   D +    +R+  +G   S +  H D   + +W+A + G K+W L+PP    FL     N  +  +T A    + ++ R   +  P      E IQ+ GE +FVPSGW H V NL  T++I  N+ +  N  I+W+
Sbjct:  113 IHYWKEYVQNGHSSRKGCLYLKDWHMARDFPEHGV---YSTPVFFSSDWLNEYWDTLEVDDYRFVYMGPKGSWTPFHADVFRSYSWSANICGRKKWLLYPPGQEDFLRDTHGNLPYD-VTSAELRDSGLFPRFEEACQP-----LEIIQEAGEIMFVPSGWHHQVYNLEDTISINHNWLNGCNIDIMWQ 292
[Close]
BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. Ensembl Medaka
Match: JMJD8 (jumonji domain containing 8 [Source:NCBI gene;Acc:101170679])

HSP 1 Score: 54.299 bits (129), Expect = 4.335e-8
Identity = 36/111 (32.43%), Postives = 51/111 (45.95%), Query Frame = 2 
Query:  344 FVIGSARSGSNIHIDPLGTSAWNALVHGYKRWCLFPPCTPKFLVKPPINKNWGRLTEASDWFNIMYKRMLLSDWPSEYAMTEAIQKPGETIFVPSGWWHVVLNLTTTVAIT 676
            F I  A +G   H    G S    +++G KRW L+PP +     +P  + N   L+    W    Y  +     P + A  E   +PGE +F P  WWH  LNL T+V I+
Sbjct:  171 FGIAGAGTGVPFHWHGAGFSE---VIYGRKRWFLYPPES-----RPHFHPNRTTLS----WLTETYPHL-----PEDEAPLECTIRPGEVLFFPDRWWHATLNLDTSVFIS 264
[Close]
BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. Ensembl Medaka
Match: JMJD8 (jumonji domain containing 8 [Source:NCBI gene;Acc:101170679])

HSP 1 Score: 54.299 bits (129), Expect = 5.139e-8
Identity = 36/111 (32.43%), Postives = 51/111 (45.95%), Query Frame = 2 
Query:  344 FVIGSARSGSNIHIDPLGTSAWNALVHGYKRWCLFPPCTPKFLVKPPINKNWGRLTEASDWFNIMYKRMLLSDWPSEYAMTEAIQKPGETIFVPSGWWHVVLNLTTTVAIT 676
            F I  A +G   H    G S    +++G KRW L+PP +     +P  + N   L+    W    Y  +     P + A  E   +PGE +F P  WWH  LNL T+V I+
Sbjct:  186 FGIAGAGTGVPFHWHGAGFSE---VIYGRKRWFLYPPES-----RPHFHPNRTTLS----WLTETYPHL-----PEDEAPLECTIRPGEVLFFPDRWWHATLNLDTSVFIS 279
[Close]
BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. Planmine SMEST
Match: SMESG000039333.1 (SMESG000039333.1)

HSP 1 Score: 472.241 bits (1214), Expect = 7.045e-168
Identity = 241/241 (100.00%), Postives = 241/241 (100.00%), Query Frame = 2 
Query:  101 YRNQSFRCGDDENDRTVSIKMKYFADYMKNNNDDSPLYVFDGSLDENKKKARLLEDYQVSGYFTEDLFSILGDKIRPPFRWFVIGSARSGSNIHIDPLGTSAWNALVHGYKRWCLFPPCTPKFLVKPPINKNWGRLTEASDWFNIMYKRMLLSDWPSEYAMTEAIQKPGETIFVPSGWWHVVLNLTTTVAITQNFCSTINFPIVWRKTVXXXXXXXXXXXXXXXEIRPDLCEIADEINVNG 823
            YRNQSFRCGDDENDRTVSIKMKYFADYMKNNNDDSPLYVFDGSLDENKKKARLLEDYQVSGYFTEDLFSILGDKIRPPFRWFVIGSARSGSNIHIDPLGTSAWNALVHGYKRWCLFPPCTPKFLVKPPINKNWGRLTEASDWFNIMYKRMLLSDWPSEYAMTEAIQKPGETIFVPSGWWHVVLNLTTTVAITQNFCSTINFPIVWRKTVKHRKKLSKLWYKKLLEIRPDLCEIADEINVNG
Sbjct:  105 YRNQSFRCGDDENDRTVSIKMKYFADYMKNNNDDSPLYVFDGSLDENKKKARLLEDYQVSGYFTEDLFSILGDKIRPPFRWFVIGSARSGSNIHIDPLGTSAWNALVHGYKRWCLFPPCTPKFLVKPPINKNWGRLTEASDWFNIMYKRMLLSDWPSEYAMTEAIQKPGETIFVPSGWWHVVLNLTTTVAITQNFCSTINFPIVWRKTVKHRKKLSKLWYKKLLEIRPDLCEIADEINVNG 345
[Close]
BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. Planmine SMEST
Match: SMESG000039333.1 (SMESG000039333.1)

HSP 1 Score: 472.241 bits (1214), Expect = 1.658e-167
Identity = 241/241 (100.00%), Postives = 241/241 (100.00%), Query Frame = 2 
Query:  101 YRNQSFRCGDDENDRTVSIKMKYFADYMKNNNDDSPLYVFDGSLDENKKKARLLEDYQVSGYFTEDLFSILGDKIRPPFRWFVIGSARSGSNIHIDPLGTSAWNALVHGYKRWCLFPPCTPKFLVKPPINKNWGRLTEASDWFNIMYKRMLLSDWPSEYAMTEAIQKPGETIFVPSGWWHVVLNLTTTVAITQNFCSTINFPIVWRKTVXXXXXXXXXXXXXXXEIRPDLCEIADEINVNG 823
            YRNQSFRCGDDENDRTVSIKMKYFADYMKNNNDDSPLYVFDGSLDENKKKARLLEDYQVSGYFTEDLFSILGDKIRPPFRWFVIGSARSGSNIHIDPLGTSAWNALVHGYKRWCLFPPCTPKFLVKPPINKNWGRLTEASDWFNIMYKRMLLSDWPSEYAMTEAIQKPGETIFVPSGWWHVVLNLTTTVAITQNFCSTINFPIVWRKTVKHRKKLSKLWYKKLLEIRPDLCEIADEINVNG
Sbjct:  129 YRNQSFRCGDDENDRTVSIKMKYFADYMKNNNDDSPLYVFDGSLDENKKKARLLEDYQVSGYFTEDLFSILGDKIRPPFRWFVIGSARSGSNIHIDPLGTSAWNALVHGYKRWCLFPPCTPKFLVKPPINKNWGRLTEASDWFNIMYKRMLLSDWPSEYAMTEAIQKPGETIFVPSGWWHVVLNLTTTVAITQNFCSTINFPIVWRKTVKHRKKLSKLWYKKLLEIRPDLCEIADEINVNG 369
[Close]
BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. Planmine SMEST
Match: SMESG000022043.1 (SMESG000022043.1)

HSP 1 Score: 318.931 bits (816), Expect = 3.873e-107
Identity = 157/240 (65.42%), Postives = 189/240 (78.75%), Query Frame = 2 
Query:  101 YRNQSFRCGDDENDRTVSIKMKYFADYMKNNNDDSPLYVFDGSLDENKKKARLLEDYQVSGYFTEDLFSILGDKIRPPFRWFVIGSARSGSNIHIDPLGTSAWNALVHGYKRWCLFPPCTPKFLVKPPINKNWGRLTEASDWFNIMYKRMLLSDWPSEYAMTEAIQKPGETIFVPSGWWHVVLNLTTTVAITQNFCSTINFPIVWRKTVXXXXXXXXXXXXXXXEIRPDLCEIADEINVN 820
            YRNQ FRCG+D++   V IKMKYF +YM  NNDDSPLY+FDG+  EN K+ARLLEDYQ+S YF EDLF + G+  RPP+RWFV+GSARSG+ IHIDPLGTSAWNALV G+KRWCLFPP TPK L+K   N+ W   +EA  WF+I+Y R    +WPSE+ M E +Q PGET+FVP GWWHVVLNL  TVA+TQNFCS+ NFP+VW KTV+ R+KLSK WY+KL E RPDL  IA++I+ N
Sbjct:  104 YRNQKFRCGEDDDGYGVKIKMKYFVNYMNENNDDSPLYIFDGNFGENPKRARLLEDYQISDYFKEDLFKLCGETRRPPYRWFVMGSARSGTGIHIDPLGTSAWNALVKGHKRWCLFPPSTPKELLKLNSNEGWKNRSEAIVWFSIVYPRCKAPNWPSEFKMIEILQNPGETVFVPGGWWHVVLNLDDTVAVTQNFCSSSNFPVVWYKTVRGRRKLSKKWYEKLKECRPDLARIAEKIDPN 343
[Close]
BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. Planmine SMEST
Match: SMESG000053108.1 (SMESG000053108.1)

HSP 1 Score: 65.4698 bits (158), Expect = 1.416e-11
Identity = 45/163 (27.61%), Postives = 73/163 (44.79%), Query Frame = 2 
Query:  248 KARLLEDYQVSGYFTEDLFSILGDKIRPPFRWFVIGSARSGSNIHIDPLGTSAWNALVHGYKRWCLFPPCTPKFL-------VKPPINKNWGRLTEASDWF----NIMYKRMLLSDWPSEYAMTEAIQKPGETIFVPSGWWHVVLNLTTTVAITQNFCSTINF 703
            + +L  D        ED F +   +IRP + + + G+  S S++H+DP   +  N ++ G K+W LFPP     L        K PIN N  +     D F    +I Y  +          + E  Q PGE + +P+GW+H   N   T+A+     ++ N+
Sbjct:  172 RPKLQSDLGTCKEIMEDYFQMFPVEIRPWWSFLLWGTRYSRSHLHMDPYNWTGTNMVISGLKQWKLFPPGQDNLLHVKLETKYKFPININ--KYNSKIDCFDPNAHIEYPSL------KSAKVLEFYQYPGELLIIPTGWFHQAFNEEITLAVAGQLMNSENY 326
[Close]
BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. Planmine SMEST
Match: SMESG000017771.1 (SMESG000017771.1)

HSP 1 Score: 48.1358 bits (113), Expect = 6.358e-6
Identity = 35/130 (26.92%), Postives = 62/130 (47.69%), Query Frame = 2 
Query:  326 RPPFRWFVIGSAR-SGSNIHIDPLGTSAWNALVHGYKRWCLFPPCTPKFLVKPPINKNW-GRLTEASDWFNIMYKRMLLSDWPSEYAMTEAIQKPGETIFVPSGWWHVVLNLTTTVAITQNFCSTINFPI 709
            +P  + + + S + S ++ HID  G+S W  +  G+K + L PP   +  +K     +W G       +F    K+  L+D    Y +     K G+TI +P+GW H V  L  ++    NF  +++ P+
Sbjct:  154 KPSVQKYCLMSMKDSWTDFHIDFGGSSVWYHMYSGHKIFYLIPP--KRRYIKA--YTSWMGEYNNRMLFFPDQIKKFSLNDQAEVYRLE---IKSGDTILLPAGWIHAVHTLEDSLVFGGNFVHSLSIPL 276
The following BLAST results are available for this feature:
BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
JMJD62.933e-9356.25jumonji domain containing 6, arginine demethylase ... [more]
JMJD65.014e-9356.25jumonji domain containing 6, arginine demethylase ... [more]
JMJD62.891e-9259.33jumonji domain containing 6, arginine demethylase ... [more]
JMJD67.055e-9259.33jumonji domain containing 6, arginine demethylase ... [more]
JMJD67.055e-9259.33jumonji domain containing 6, arginine demethylase ... [more]
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BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
psr-17.889e-8657.08Bifunctional arginine demethylase and lysyl-hydrox... [more]
psr-11.191e-8557.08Bifunctional arginine demethylase and lysyl-hydrox... [more]
psr-18.858e-7857.21Bifunctional arginine demethylase and lysyl-hydrox... [more]
jmjd-42.908e-1125.81JuMonJi (Transcription factor) Domain protein [So... [more]
C27F2.91.856e-729.73pep chromosome:WBcel235:III:4961817:4963092:-1 gen... [more]
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BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 4
Match NameE-valueIdentityDescription
PSR2.079e-8854.58gene:FBgn0038948 transcript:FBtr0084239[more]
PSR3.055e-8854.58gene:FBgn0038948 transcript:FBtr0330378[more]
JMJD42.882e-1229.14gene:FBgn0032671 transcript:FBtr0081062[more]
JMJD42.882e-1229.14gene:FBgn0032671 transcript:FBtr0343823[more]
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BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 3
Match NameE-valueIdentityDescription
jmjd67.184e-9657.08jumonji domain containing 6, arginine demethylase ... [more]
jmjd45.914e-1428.42jumonji domain containing 4 [Source:NCBI gene;Acc:... [more]
JMJD84.598e-627.69jumonji domain containing 8 [Source:NCBI gene;Acc:... [more]
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BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
jmjd65.848e-9154.58jumonji domain containing 6 [Source:NCBI gene;Acc:... [more]
lman21.463e-1229.63lectin, mannose-binding 2 [Source:Xenbase;Acc:XB-G... [more]
lman21.475e-1229.63lectin, mannose-binding 2 [Source:Xenbase;Acc:XB-G... [more]
lman21.595e-1229.63lectin, mannose-binding 2 [Source:Xenbase;Acc:XB-G... [more]
JMJD81.043e-630.89jumonji domain containing 8 [Source:NCBI gene;Acc:... [more]
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BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Jmjd69.076e-9356.25jumonji domain containing 6 [Source:MGI Symbol;Acc... [more]
Jmjd62.540e-9259.33jumonji domain containing 6 [Source:MGI Symbol;Acc... [more]
Jmjd67.761e-9259.33jumonji domain containing 6 [Source:MGI Symbol;Acc... [more]
Jmjd68.037e-7055.37jumonji domain containing 6 [Source:MGI Symbol;Acc... [more]
Jmjd66.213e-3055.32jumonji domain containing 6 [Source:MGI Symbol;Acc... [more]
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BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q6PFM0|JMJD6_DANRE5.423e-9557.08Bifunctional arginine demethylase and lysyl-hydrox... [more]
sp|Q6GND3|JMD6A_XENLA1.511e-9356.67Bifunctional arginine demethylase and lysyl-hydrox... [more]
sp|Q5R6G2|JMJD6_PONAB1.408e-9256.25Bifunctional arginine demethylase and lysyl-hydrox... [more]
sp|Q6NYC1|JMJD6_HUMAN1.408e-9256.25Bifunctional arginine demethylase and lysyl-hydrox... [more]
sp|Q5ZMK5|JMJD6_CHICK2.208e-9256.67Bifunctional arginine demethylase and lysyl-hydrox... [more]
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BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A4E0RA735.487e-9661.09Bifunctional arginine demethylase and lysyl-hydrox... [more]
A0A504YFI43.088e-9561.09Bifunctional arginine demethylase and lysyl-hydrox... [more]
A0A267GDN64.058e-9457.08JmjC domain-containing protein OS=Macrostomum lign... [more]
A0A443SVG24.284e-9458.75Bifunctional arginine demethylase and lysyl-hydrox... [more]
V3ZV575.794e-9460.67JmjC domain-containing protein OS=Lottia gigantea ... [more]
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BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
jmjd67.651e-9456.25jumonji domain containing 6, arginine demethylase ... [more]
jmjd44.003e-1327.37jumonji domain containing 4 [Source:NCBI gene;Acc:... [more]
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BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2
Match NameE-valueIdentityDescription
jmjd62.081e-9255.83jumonji domain containing 6, arginine demethylase ... [more]
jmjd42.393e-1126.90jumonji domain containing 4 [Source:NCBI gene;Acc:... [more]
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BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO410232.377e-8550.83Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO306571.065e-1526.77Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO459763.255e-1430.83Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO268531.385e-1135.58Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO483931.931e-1025.77Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 4
Match NameE-valueIdentityDescription
jmjd62.598e-9355.83jumonji domain containing 6, arginine demethylase ... [more]
jmjd44.379e-1226.98jumonji domain containing 4 [Source:NCBI gene;Acc:... [more]
JMJD84.335e-832.43jumonji domain containing 8 [Source:NCBI gene;Acc:... [more]
JMJD85.139e-832.43jumonji domain containing 8 [Source:NCBI gene;Acc:... [more]
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BLAST of Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000039333.17.045e-168100.00SMESG000039333.1[more]
SMESG000039333.11.658e-167100.00SMESG000039333.1[more]
SMESG000022043.13.873e-10765.42SMESG000022043.1[more]
SMESG000053108.11.416e-1127.61SMESG000053108.1[more]
SMESG000017771.16.358e-626.92SMESG000017771.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30019142 ID=SMED30019142|Name=Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6|organism=Schmidtea mediterranea sexual|type=transcript|length=1007bp
AAAATTGGCCCGCCATTAAGAAATGGAAACTAGCAGTTATGGATTATTCA
ATATTAAATTTTATTGTTAATTAATTATTTAAAAGAATTTAAAACTAAAA
TATCGCAATCAATCTTTTCGTTGCGGCGATGATGAAAACGACAGAACGGT
CAGTATCAAAATGAAGTATTTTGCAGATTATATGAAAAACAACAATGATG
ATTCTCCTTTGTACGTTTTTGATGGGTCTCTCGACGAGAACAAGAAAAAA
GCCCGATTACTTGAAGATTATCAAGTGAGTGGTTATTTTACTGAAGACCT
TTTTAGTATTTTAGGAGACAAAATAAGACCCCCGTTCAGATGGTTTGTTA
TTGGGTCAGCTCGATCCGGCTCAAATATTCATATAGATCCTTTAGGGACA
AGTGCTTGGAATGCATTAGTACACGGATATAAACGGTGGTGCTTATTTCC
TCCTTGTACACCGAAATTCCTCGTTAAACCTCCTATTAATAAAAATTGGG
GCAGACTTACCGAAGCAAGCGATTGGTTTAATATCATGTATAAACGAATG
TTGTTGTCCGATTGGCCTTCCGAATATGCTATGACAGAAGCAATTCAAAA
ACCAGGAGAAACTATATTTGTTCCCAGTGGTTGGTGGCATGTTGTTCTCA
ATTTAACCACAACCGTTGCAATTACCCAAAATTTTTGCAGCACGATTAAT
TTTCCCATAGTATGGCGTAAAACTGTGAAACATAGAAAAAAGTTGTCCAA
ATTATGGTATAAAAAATTGTTAGAAATACGACCAGATCTCTGTGAAATTG
CTGATGAAATAAATGTAAATGGATCTGACGAAAACTACTATTCATATTCA
TCATCTTCGGAATCTGATTCATCTGTTTTGACCAGTAATCCGTCAAGGTC
AACATCTTGAGAACTCTCTAGCACATTTTCTGAGGTAGACAAAACTCGTT
CTGTTGACAAATAAATTCAAAGGATTTTATACTACCTTTAATTTAATTCA
AATTTCA
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protein sequence of SMED30019142-orf-1

>SMED30019142-orf-1 ID=SMED30019142-orf-1|Name=SMED30019142-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=250bp
MKYFADYMKNNNDDSPLYVFDGSLDENKKKARLLEDYQVSGYFTEDLFSI
LGDKIRPPFRWFVIGSARSGSNIHIDPLGTSAWNALVHGYKRWCLFPPCT
PKFLVKPPINKNWGRLTEASDWFNIMYKRMLLSDWPSEYAMTEAIQKPGE
TIFVPSGWWHVVLNLTTTVAITQNFCSTINFPIVWRKTVKHRKKLSKLWY
KKLLEIRPDLCEIADEINVNGSDENYYSYSSSSESDSSVLTSNPSRSTS*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0003713transcription coactivator activity
GO:0032451demethylase activity
GO:0032452histone demethylase activity
GO:0035515oxidative RNA demethylase activity
GO:0003723RNA binding
GO:0003727single-stranded RNA binding
GO:0016491oxidoreductase activity
GO:0033746histone demethylase activity (H3-R2 specific)
GO:0033749histone demethylase activity (H4-R3 specific)
GO:0046872metal ion binding
GO:0051213dioxygenase activity
GO:0070815peptidyl-lysine 5-dioxygenase activity
Vocabulary: cellular component
TermDefinition
GO:0005737cytoplasm
GO:0005634nucleus
GO:0005654nucleoplasm
GO:0005730nucleolus
Vocabulary: biological process
TermDefinition
GO:0006325chromatin organization
GO:0006482protein demethylation
GO:0035513oxidative RNA demethylation
GO:0045893positive regulation of transcription, DNA-templated
GO:0045944positive regulation of transcription from RNA polymerase II promoter
GO:0051260protein homooligomerization
GO:0002040sprouting angiogenesis
GO:0006351transcription, DNA-templated
GO:0006355regulation of transcription, DNA-templated
GO:0006397mRNA processing
GO:0006909phagocytosis
GO:0007275multicellular organism development
GO:0008380RNA splicing
GO:0016569covalent chromatin modification
GO:0018395peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine
GO:0030154cell differentiation
GO:0048024regulation of mRNA splicing, via spliceosome
GO:0055114oxidation-reduction process
GO:0070078histone H3-R2 demethylation
GO:0070079histone H4-R3 demethylation
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0002089reproductive organ
PLANA:0002109X1 cell
Vocabulary: INTERPRO
TermDefinition
IPR003347JmjC_dom
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR003347JmjC domainSMARTSM00558cupin_9coord: 28..192
e-value: 1.3E-29
score: 114.4
IPR003347JmjC domainPFAMPF02373JmjCcoord: 61..175
e-value: 1.4E-18
score: 67.4
IPR003347JmjC domainPROSITEPS51184JMJCcoord: 28..192
score: 30.755
NoneNo IPR availableGENE3DG3DSA:2.60.120.650coord: 1..177
e-value: 1.8E-59
score: 203.4
NoneNo IPR availableGENE3DG3DSA:1.20.1280.270coord: 178..222
e-value: 3.5E-16
score: 60.4
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 229..249
NoneNo IPR availablePANTHERPTHR12480:SF32BIFUNCTIONAL ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD6coord: 1..194
NoneNo IPR availablePANTHERPTHR12480PHOSPHATIDYLSERINE RECEPTORcoord: 1..194
NoneNo IPR availableSUPERFAMILYSSF51197Clavaminate synthase-likecoord: 1..211