protein dispatched homolog 1

Overview
Nameprotein dispatched homolog 1
Smed IDSMED30019084
Length (bp)1317
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of protein dispatched homolog 1 (SMED30019084) t-SNE clustered cells

Violin plots show distribution of expression levels for protein dispatched homolog 1 (SMED30019084) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of protein dispatched homolog 1 (SMED30019084) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for protein dispatched homolog 1 (SMED30019084) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30019084

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 1

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
parenchymal cellSMED30019084h1SMcG0005009 dd_Smed_v4_11945_0_2dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of protein dispatched homolog 1 vs. Ensembl Human
Match: DISP1 (dispatched RND transporter family member 1 [Source:HGNC Symbol;Acc:HGNC:19711])

HSP 1 Score: 62.3882 bits (150), Expect = 1.060e-9
Identity = 41/155 (26.45%), Postives = 72/155 (46.45%), Query Frame = 3 
Query:  654 GSAIAGVLSGLIISFPIILMATLNFHTFLIIIIGTCLSTLSVTSLIYVTGWNLGLLESINLTVVVGLTIDYLVHMGLAYNSSQKEHRDERTEDMLEEMGVSILSGMXXXXXXXXXXXXXXXXXXXXXGVFVFATIFSAGIYSIIFLPCMFLVFGP 1118
            G+ IA  LS + ++F ++L+ T N    L  II    +       + + GW L +LES+ ++V VGL++D+ VH G+AY  +    R+ +    L  +G ++     TT  +   +         Q G F+   +  +  ++  F  CM    GP
Sbjct:  983 GTLIAMGLS-VAVAFSVMLLTTWNIIISLYAIISIAGTIFVTVGSLVLLGWELNVLESVTISVAVGLSVDFAVHYGVAYRLAPDPDREGKVIFSLSRVGSAMAMAALTTFVAGAMMMPSTVLAYTQLGTFMMLIMCISWAFATFFFQCMCRCLGP 1136
[Close]
BLAST of protein dispatched homolog 1 vs. Ensembl Zebrafish
Match: disp1 (dispatched homolog 1 (Drosophila) [Source:NCBI gene;Acc:619201])

HSP 1 Score: 70.0922 bits (170), Expect = 2.452e-12
Identity = 43/155 (27.74%), Postives = 75/155 (48.39%), Query Frame = 3 
Query:  654 GSAIAGVLSGLIISFPIILMATLNFHTFLIIIIGTCLSTLSVTSLIYVTGWNLGLLESINLTVVVGLTIDYLVHMGLAYNSSQKEHRDERTEDMLEEMGVSILSGMXXXXXXXXXXXXXXXXXXXXXGVFVFATIFSAGIYSIIFLPCMFLVFGP 1118
            G+ IA  LS ++++F ++L+ T N    L  II    +       + + GW L +LES+ ++V VGL++D+ VH G+AY  + +  R+ +    L  MG +I     TT  +   +         Q G F+   +  +  ++  F  CM  + GP
Sbjct:  965 GTLIAMALS-VVVAFSVMLLTTWNIIISLYAIISIAGTIFVTVGSLVLLGWELNVLESVTISVAVGLSVDFAVHYGVAYRLAPEPDREGKVVFSLSRMGSAIAMAALTTFVAGAMMMPSTVLAYTQLGTFLMLIMCISWAFATFFFQCMCRLLGP 1118
[Close]
BLAST of protein dispatched homolog 1 vs. Ensembl Zebrafish
Match: disp1 (dispatched homolog 1 (Drosophila) [Source:NCBI gene;Acc:619201])

HSP 1 Score: 70.0922 bits (170), Expect = 2.452e-12
Identity = 43/155 (27.74%), Postives = 75/155 (48.39%), Query Frame = 3 
Query:  654 GSAIAGVLSGLIISFPIILMATLNFHTFLIIIIGTCLSTLSVTSLIYVTGWNLGLLESINLTVVVGLTIDYLVHMGLAYNSSQKEHRDERTEDMLEEMGVSILSGMXXXXXXXXXXXXXXXXXXXXXGVFVFATIFSAGIYSIIFLPCMFLVFGP 1118
            G+ IA  LS ++++F ++L+ T N    L  II    +       + + GW L +LES+ ++V VGL++D+ VH G+AY  + +  R+ +    L  MG +I     TT  +   +         Q G F+   +  +  ++  F  CM  + GP
Sbjct:  965 GTLIAMALS-VVVAFSVMLLTTWNIIISLYAIISIAGTIFVTVGSLVLLGWELNVLESVTISVAVGLSVDFAVHYGVAYRLAPEPDREGKVVFSLSRMGSAIAMAALTTFVAGAMMMPSTVLAYTQLGTFLMLIMCISWAFATFFFQCMCRLLGP 1118
[Close]
BLAST of protein dispatched homolog 1 vs. Ensembl Xenopus
Match: DISP1 (dispatched RND transporter family member 1 [Source:NCBI gene;Acc:100496804])

HSP 1 Score: 54.6842 bits (130), Expect = 2.897e-7
Identity = 46/163 (28.22%), Postives = 77/163 (47.24%), Query Frame = 3 
Query:  654 GSAIAGVLSGLIISFPIILMATLNFHTFLIIIIGTCLSTLSVTSLIYVT-------GWNLGLLESINLTVVVGLTIDYLVHMGLAYNSSQKEHRDERTEDMLEEMGVSILSGMXXXXXXXXXXXXXXXXXXXXXGVFVFATIFSAGIYSIIFLPCMFLVFGPS 1121
            G+ IA  LS + ++F ++L+ T N       II +  + +S+   I+VT       GW L +LES+ ++V VGL++D+ VH G+AY  +    R+ +    L  MG +I     TT  +   +         Q G F+   +  +  ++  F  CM    GP 
Sbjct:  979 GTLIAMGLS-VAVAFSVMLLTTWN-------IILSVYAIVSIAGTIFVTVGSLVLLGWELNVLESVTISVAVGLSVDFAVHYGVAYRLAPDPDREGKVVFSLSRMGSAIAMAALTTFVAGAMMMPSTVLAYTQLGTFMMLIMCVSWAFATFFFQCMCRCLGPQ 1133
[Close]
BLAST of protein dispatched homolog 1 vs. Ensembl Mouse
Match: Disp1 (dispatched RND transporter family member 1 [Source:MGI Symbol;Acc:MGI:1916147])

HSP 1 Score: 64.3142 bits (155), Expect = 2.074e-10
Identity = 41/155 (26.45%), Postives = 72/155 (46.45%), Query Frame = 3 
Query:  654 GSAIAGVLSGLIISFPIILMATLNFHTFLIIIIGTCLSTLSVTSLIYVTGWNLGLLESINLTVVVGLTIDYLVHMGLAYNSSQKEHRDERTEDMLEEMGVSILSGMXXXXXXXXXXXXXXXXXXXXXGVFVFATIFSAGIYSIIFLPCMFLVFGP 1118
            G+ IA  LS + ++F ++L+ T N    L  I+    +       + + GW L +LES+ ++V VGL++D+ VH G+AY  +    R+ +    L  MG +I     TT  +   +         Q G F+   +  +  ++  F  C+    GP
Sbjct:  981 GTLIAMGLS-VAVAFSVMLLTTWNIIISLYAIVSIAGTIFVTVGSLVLLGWELNVLESVTISVAVGLSVDFAVHYGVAYRLAPDPDREGKVIFSLSRMGSAIAMAALTTFVAGAMMMPSTVLAYTQLGTFMMLVMCVSWAFATFFFQCLCRCLGP 1134
[Close]
BLAST of protein dispatched homolog 1 vs. Ensembl Mouse
Match: Disp1 (dispatched RND transporter family member 1 [Source:MGI Symbol;Acc:MGI:1916147])

HSP 1 Score: 64.3142 bits (155), Expect = 2.074e-10
Identity = 41/155 (26.45%), Postives = 72/155 (46.45%), Query Frame = 3 
Query:  654 GSAIAGVLSGLIISFPIILMATLNFHTFLIIIIGTCLSTLSVTSLIYVTGWNLGLLESINLTVVVGLTIDYLVHMGLAYNSSQKEHRDERTEDMLEEMGVSILSGMXXXXXXXXXXXXXXXXXXXXXGVFVFATIFSAGIYSIIFLPCMFLVFGP 1118
            G+ IA  LS + ++F ++L+ T N    L  I+    +       + + GW L +LES+ ++V VGL++D+ VH G+AY  +    R+ +    L  MG +I     TT  +   +         Q G F+   +  +  ++  F  C+    GP
Sbjct:  981 GTLIAMGLS-VAVAFSVMLLTTWNIIISLYAIVSIAGTIFVTVGSLVLLGWELNVLESVTISVAVGLSVDFAVHYGVAYRLAPDPDREGKVIFSLSRMGSAIAMAALTTFVAGAMMMPSTVLAYTQLGTFMMLVMCVSWAFATFFFQCLCRCLGP 1134
[Close]
BLAST of protein dispatched homolog 1 vs. Ensembl Mouse
Match: Disp1 (dispatched RND transporter family member 1 [Source:MGI Symbol;Acc:MGI:1916147])

HSP 1 Score: 64.3142 bits (155), Expect = 2.074e-10
Identity = 41/155 (26.45%), Postives = 72/155 (46.45%), Query Frame = 3 
Query:  654 GSAIAGVLSGLIISFPIILMATLNFHTFLIIIIGTCLSTLSVTSLIYVTGWNLGLLESINLTVVVGLTIDYLVHMGLAYNSSQKEHRDERTEDMLEEMGVSILSGMXXXXXXXXXXXXXXXXXXXXXGVFVFATIFSAGIYSIIFLPCMFLVFGP 1118
            G+ IA  LS + ++F ++L+ T N    L  I+    +       + + GW L +LES+ ++V VGL++D+ VH G+AY  +    R+ +    L  MG +I     TT  +   +         Q G F+   +  +  ++  F  C+    GP
Sbjct:  981 GTLIAMGLS-VAVAFSVMLLTTWNIIISLYAIVSIAGTIFVTVGSLVLLGWELNVLESVTISVAVGLSVDFAVHYGVAYRLAPDPDREGKVIFSLSRMGSAIAMAALTTFVAGAMMMPSTVLAYTQLGTFMMLVMCVSWAFATFFFQCLCRCLGP 1134
[Close]
BLAST of protein dispatched homolog 1 vs. UniProt/SwissProt
Match: sp|Q6R5J2|DISP1_DANRE (Protein dispatched homolog 1 OS=Danio rerio OX=7955 GN=disp1 PE=2 SV=1)

HSP 1 Score: 70.0922 bits (170), Expect = 1.851e-11
Identity = 43/155 (27.74%), Postives = 75/155 (48.39%), Query Frame = 3 
Query:  654 GSAIAGVLSGLIISFPIILMATLNFHTFLIIIIGTCLSTLSVTSLIYVTGWNLGLLESINLTVVVGLTIDYLVHMGLAYNSSQKEHRDERTEDMLEEMGVSILSGMXXXXXXXXXXXXXXXXXXXXXGVFVFATIFSAGIYSIIFLPCMFLVFGP 1118
            G+ IA  LS ++++F ++L+ T N    L  II    +       + + GW L +LES+ ++V VGL++D+ VH G+AY  + +  R+ +    L  MG +I     TT  +   +         Q G F+   +  +  ++  F  CM  + GP
Sbjct:  965 GTLIAMALS-VVVAFSVMLLTTWNIIISLYAIISIAGTIFVTVGSLVLLGWELNVLESVTISVAVGLSVDFAVHYGVAYRLAPEPDREGKVVFSLSRMGSAIAMAALTTFVAGAMMMPSTVLAYTQLGTFLMLIMCISWAFATFFFQCMCRLLGP 1118
[Close]
BLAST of protein dispatched homolog 1 vs. UniProt/SwissProt
Match: sp|Q3TDN0|DISP1_MOUSE (Protein dispatched homolog 1 OS=Mus musculus OX=10090 GN=Disp1 PE=1 SV=2)

HSP 1 Score: 64.3142 bits (155), Expect = 1.451e-9
Identity = 41/155 (26.45%), Postives = 72/155 (46.45%), Query Frame = 3 
Query:  654 GSAIAGVLSGLIISFPIILMATLNFHTFLIIIIGTCLSTLSVTSLIYVTGWNLGLLESINLTVVVGLTIDYLVHMGLAYNSSQKEHRDERTEDMLEEMGVSILSGMXXXXXXXXXXXXXXXXXXXXXGVFVFATIFSAGIYSIIFLPCMFLVFGP 1118
            G+ IA  LS + ++F ++L+ T N    L  I+    +       + + GW L +LES+ ++V VGL++D+ VH G+AY  +    R+ +    L  MG +I     TT  +   +         Q G F+   +  +  ++  F  C+    GP
Sbjct:  981 GTLIAMGLS-VAVAFSVMLLTTWNIIISLYAIVSIAGTIFVTVGSLVLLGWELNVLESVTISVAVGLSVDFAVHYGVAYRLAPDPDREGKVIFSLSRMGSAIAMAALTTFVAGAMMMPSTVLAYTQLGTFMMLVMCVSWAFATFFFQCLCRCLGP 1134
[Close]
BLAST of protein dispatched homolog 1 vs. UniProt/SwissProt
Match: sp|Q96F81|DISP1_HUMAN (Protein dispatched homolog 1 OS=Homo sapiens OX=9606 GN=DISP1 PE=1 SV=3)

HSP 1 Score: 62.3882 bits (150), Expect = 5.089e-9
Identity = 41/155 (26.45%), Postives = 72/155 (46.45%), Query Frame = 3 
Query:  654 GSAIAGVLSGLIISFPIILMATLNFHTFLIIIIGTCLSTLSVTSLIYVTGWNLGLLESINLTVVVGLTIDYLVHMGLAYNSSQKEHRDERTEDMLEEMGVSILSGMXXXXXXXXXXXXXXXXXXXXXGVFVFATIFSAGIYSIIFLPCMFLVFGP 1118
            G+ IA  LS + ++F ++L+ T N    L  II    +       + + GW L +LES+ ++V VGL++D+ VH G+AY  +    R+ +    L  +G ++     TT  +   +         Q G F+   +  +  ++  F  CM    GP
Sbjct:  983 GTLIAMGLS-VAVAFSVMLLTTWNIIISLYAIISIAGTIFVTVGSLVLLGWELNVLESVTISVAVGLSVDFAVHYGVAYRLAPDPDREGKVIFSLSRVGSAMAMAALTTFVAGAMMMPSTVLAYTQLGTFMMLIMCISWAFATFFFQCMCRCLGP 1136
[Close]
BLAST of protein dispatched homolog 1 vs. TrEMBL
Match: A0A1S3HIR2 (uncharacterized protein LOC106155638 OS=Lingula unguis OX=7574 GN=LOC106155638 PE=4 SV=1)

HSP 1 Score: 103.219 bits (256), Expect = 1.428e-19
Identity = 61/164 (37.20%), Postives = 101/164 (61.59%), Query Frame = 3 
Query:  648 LIGSAIAGVLSGLIISFPIILMATLNFHTFLIIIIGTCLSTLSVTSLIYVTGWNLGLLESINLTVVVGLTIDYLVHMGLAYNSSQKEHRDERTEDMLEEMGVSILSGMXXXXXXXXXXXXXXXXXXXXXGVFVFATIFSAGIYSIIFLPCMFLVFGPSQGRGDF 1139
            L  +A+ G++ G+ +SFPI++ AT N     +  +   + T+ V  +I + GW LG+L S+NL +VVGL +DY+VH+   Y+ S    R  R  DML+ +G+S+LSG +TTLG+S F+ F + +F  QFG+F+F+ I  + ++S++F   +  + GP    G  
Sbjct: 1164 LASTALMGIVIGISLSFPILVFATQNIIMGFLATLTMGMVTVCVVGVIPMVGWKLGVLTSLNLCLVVGLAVDYVVHLAEGYHLSPHRDRLGRVRDMLDHVGISVLSGATTTLGASIFMMFAEIQFYVQFGIFIFSVIGFSILFSLLFFTTLLAIAGPQGDTGSL 1327
[Close]
BLAST of protein dispatched homolog 1 vs. TrEMBL
Match: A0A1S3ID80 (protein dispatched homolog 1 OS=Lingula unguis OX=7574 GN=LOC106163238 PE=4 SV=1)

HSP 1 Score: 97.4413 bits (241), Expect = 9.307e-18
Identity = 47/108 (43.52%), Postives = 73/108 (67.59%), Query Frame = 3 
Query:  645 MLIGSAIAGVLSGLIISFPIILMATLNFHTFLIIIIGTCLSTLSVTSLIYVTGWNLGLLESINLTVVVGLTIDYLVHMGLAYNSSQKEHRDERTEDMLEEMGVSILSG 968
            +L   A+ G++ G+ I++PI+++AT+N  T  + ++  C  T SV   + V GW LG+LES+N  +VVGL +DY+VH+   Y+ S K  R  R +DMLEE+G+S+LSG
Sbjct:  863 LLNNQALLGIVIGVAIAYPILIVATMNIITGTLAVLTICFITASVVGTVPVVGWKLGVLESLNFVLVVGLAVDYVVHLAEGYSRSMKRDRLGRVKDMLEEVGISVLSG 970
[Close]
BLAST of protein dispatched homolog 1 vs. TrEMBL
Match: K1RCQ5 (Dispatched-like protein 1 OS=Crassostrea gigas OX=29159 GN=CGI_10004583 PE=4 SV=1)

HSP 1 Score: 97.4413 bits (241), Expect = 1.033e-17
Identity = 71/180 (39.44%), Postives = 107/180 (59.44%), Query Frame = 3 
Query:  648 LIGSAIAGVLSGLIISFPIILMATLNFHTFLIIIIGTCLSTLSVTSLIYVTGWNLGLLESINLTVVVGLTIDYLVHMGLAYNSSQKEHRDERTEDMLEEMGVSILSGMXXXXXXXXXXXXXXXXXXXXXGVFVFATIFSAGIYSIIFLPCMFLVFGPSQGRGDFHCDFYRCMPCFKIEKR 1187
            L  +A+ G+L G+ ++FPI+ ++T+N     +  +  C +T+ V  +I + GW LGLL S+N+ +VVGL +DY+VH+   Y  S    R  RT DMLEEMG S+ SG  TTLG+S F+F  + +F  QFGVF+F TI  + I+S+     +  + GP    G+    F +C    K+ KR
Sbjct:  921 LADNALLGILIGVGLAFPILSLSTMNVLIGFLATLSICCTTVCVIGVIPLAGWKLGLLTSLNMCLVVGLAVDYVVHLAEGYTLSLHTDRYSRTRDMLEEMGPSVFSGACTTLGASLFMFAAEIQFFMQFGVFMFCTIGFSLIFSLGLFTLLVGLIGPQGNTGNLKVLFRKCKE--KLLKR 1098
[Close]
BLAST of protein dispatched homolog 1 vs. TrEMBL
Match: A0A210R352 (Protein dispatched-like 1 OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT10470 PE=4 SV=1)

HSP 1 Score: 96.6709 bits (239), Expect = 1.914e-17
Identity = 70/185 (37.84%), Postives = 107/185 (57.84%), Query Frame = 3 
Query:  657 SAIAGVLSGLIISFPIILMATLNFHTFLIIIIGTCLSTLSVTSLIYVTGWNLGLLESINLTVVVGLTIDYLVHMGLAYNSSQKEHRDERTEDMLEEMGVSILSGMXXXXXXXXXXXXXXXXXXXXXGVFVFATI-----FSAGIYSIIFLPCMFLVFGPSQGRGDFHCDFYRCMPCFKIEKRSEK 1196
            +A+ G+  G+ ++FPI+ ++T+N     +  +  C +T+ V  +I   GW LGLL S+N+T++VGL +DY+VH+   Y +S  + R  RT DMLEEM  S+ SG  TTLG++ F+F  +  F  QFG+F+F TI     FS G++S++    M L+ GP    G          P F   KR+ K
Sbjct:  911 NAVTGIAVGVSLAFPILCLSTMNVIVGSLATLSICCTTICVIGVIPTAGWRLGLLTSLNMTMLVGLAVDYVVHLAEGYRNSLHKDRLHRTRDMLEEMATSVFSGACTTLGAALFMFLAKITFFMQFGIFLFCTIGFSLFFSLGLFSVL----MGLI-GPQNDTGSLR-------PIFNFIKRTLK 1083
[Close]
BLAST of protein dispatched homolog 1 vs. TrEMBL
Match: R7U147 (SSD domain-containing protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_185181 PE=4 SV=1)

HSP 1 Score: 96.2857 bits (238), Expect = 2.361e-17
Identity = 70/164 (42.68%), Postives = 102/164 (62.20%), Query Frame = 3 
Query:  633 K*NTMLIGSAIAGVLSGLIISFPIILMATLNFHTFLIIIIGTCLSTLSVTSLIYVTGWNLGLLESINLTVVVGLTIDYLVHMGLAYNSSQKEHRDERTEDMLEEMGVSILSGMXXXXXXXXXXXXXXXXXXXXXGVFVFATIFSAGIYSIIFLPCMFLVFGPSQ 1124
            K    L+ +A+ G++ GL  + PI+++AT N  T L+     C     V  +I + GW LG+LES+NL +VVGL++DY+VH+   Y+ S    R  R  DMLEE+G+SI+SG  TTLG+SFFL F Q  F  QFG+F+F+TI  + +++ IF   +  V GP  
Sbjct:  849 KVQKKLVSTAVMGIMVGLCCALPILIIATHNIITGLLATFSICCVITCVIGVIPMAGWKLGMLESLNLVLVVGLSVDYVVHLAEGYSRSLHTDRLGRLHDMLEEVGISIVSGAFTTLGASFFLLFAQILFFTQFGLFMFSTIGLSLLFACIFFSTIMGVIGPQN 1012
[Close]
BLAST of protein dispatched homolog 1 vs. Ensembl Cavefish
Match: disp1 (dispatched RND transporter family member 1 [Source:NCBI gene;Acc:103035669])

HSP 1 Score: 68.1662 bits (165), Expect = 9.112e-12
Identity = 49/184 (26.63%), Postives = 85/184 (46.20%), Query Frame = 3 
Query:  654 GSAIAGVLSGLIISFPIILMATLNFHTFLIIIIGTCLSTLSVTSLIYVT-------GWNLGLLESINLTVVVGLTIDYLVHMGLAYNSSQKEHRDERTEDMLEEMGVSILSGMXXXXXXXXXXXXXXXXXXXXXGVFVFATIFSAGIYSIIFLPCMFLVFGPSQGRGD------FHCDFYRCMP 1166
            G+ IA  LS ++++F ++L+ T N       II +  + +S+   I+VT       GW L +LES+ ++V VGL++D+ VH G+AY  + +  R+ +    L  MG +I     TT  +   +         Q G F+   +  +  ++  F  CM    GP    G       + C  ++  P
Sbjct:  981 GTLIAMALS-VMVAFSVMLLTTWN-------IIISFYAIISIAGTIFVTVGSLVLLGWELNVLESVTISVAVGLSVDFAVHYGVAYRLAPEPDREGKVVFSLSRMGSAIAMAALTTFVAGAMMMPSTVLAYTQLGTFLMLIMCISWAFATFFFQCMCCCLGPQGTCGQIPMPKAYKCHAFKANP 1156
[Close]
BLAST of protein dispatched homolog 1 vs. Ensembl Cavefish
Match: disp1 (dispatched RND transporter family member 1 [Source:NCBI gene;Acc:103035669])

HSP 1 Score: 68.1662 bits (165), Expect = 9.124e-12
Identity = 49/184 (26.63%), Postives = 85/184 (46.20%), Query Frame = 3 
Query:  654 GSAIAGVLSGLIISFPIILMATLNFHTFLIIIIGTCLSTLSVTSLIYVT-------GWNLGLLESINLTVVVGLTIDYLVHMGLAYNSSQKEHRDERTEDMLEEMGVSILSGMXXXXXXXXXXXXXXXXXXXXXGVFVFATIFSAGIYSIIFLPCMFLVFGPSQGRGD------FHCDFYRCMP 1166
            G+ IA  LS ++++F ++L+ T N       II +  + +S+   I+VT       GW L +LES+ ++V VGL++D+ VH G+AY  + +  R+ +    L  MG +I     TT  +   +         Q G F+   +  +  ++  F  CM    GP    G       + C  ++  P
Sbjct:  991 GTLIAMALS-VMVAFSVMLLTTWN-------IIISFYAIISIAGTIFVTVGSLVLLGWELNVLESVTISVAVGLSVDFAVHYGVAYRLAPEPDREGKVVFSLSRMGSAIAMAALTTFVAGAMMMPSTVLAYTQLGTFLMLIMCISWAFATFFFQCMCCCLGPQGTCGQIPMPKAYKCHAFKANP 1166
[Close]
BLAST of protein dispatched homolog 1 vs. Ensembl Sea Lamprey
Match: disp1 (dispatched homolog 1 (Drosophila) [Source:NCBI gene;Acc:619201])

HSP 1 Score: 51.2174 bits (121), Expect = 3.354e-7
Identity = 26/90 (28.89%), Postives = 47/90 (52.22%), Query Frame = 3 
Query:  690 ISFPIILMATLNFHTFLIIIIGTCLSTLSVTSLIYVTGWNLGLLESINLTVVVGLTIDYLVHMGLAYNSSQKEHRDERTEDMLEEMGVSI 959
            ++F ++L+ T +    +  ++    S    T  + + GW L +LES+ ++V VGL +D+ VH G+AY  +    R  R    L  MG ++
Sbjct:  471 LAFGVMLLTTRSLAVSVYALLAIAGSIAVTTGSLALLGWELNVLESVTVSVAVGLAVDFAVHYGVAYRLAPGPGRRARVSFSLGRMGPAV 560
[Close]
BLAST of protein dispatched homolog 1 vs. Ensembl Nematostella
Match: EDO46800 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RP59])

HSP 1 Score: 73.9442 bits (180), Expect = 4.414e-14
Identity = 41/108 (37.96%), Postives = 67/108 (62.04%), Query Frame = 3 
Query:  645 MLIGSAIAGVLSGLIISFPIILMATLNFHTFLIIIIGTCLSTLSVTSLIYVTGWNLGLLESINLTVVVGLTIDYLVHMGLAYNSSQKEHRDERTEDMLEEMGVSILSG 968
            +L+ +A  G+L  L ++FPI+L+   N+   L+ I+     T+ V   I + GW LG+LES+NLT+VVGL +DY+VH+   Y +     R +R +  L  +G+S++SG
Sbjct:  808 VLVENATRGILISLCLTFPILLLMLGNWAVALLCILTISCITVGVIGFITMFGWKLGVLESLNLTLVVGLAVDYVVHLADCYVNCPSACRLDRVKFTLGHVGISVISG 915
[Close]
BLAST of protein dispatched homolog 1 vs. Ensembl Nematostella
Match: EDO46801 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RP60])

HSP 1 Score: 72.0182 bits (175), Expect = 2.135e-13
Identity = 41/112 (36.61%), Postives = 65/112 (58.04%), Query Frame = 3 
Query:  633 K*NTMLIGSAIAGVLSGLIISFPIILMATLNFHTFLIIIIGTCLSTLSVTSLIYVTGWNLGLLESINLTVVVGLTIDYLVHMGLAYNSSQKEHRDERTEDMLEEMGVSILSG 968
            K   +L  +A+ G+L  L ++  ++ + T N+   L+        T+ V   I + GW LG+LES+NLT+VVGL +DY+VH+   Y  S    R ++T D L  +G+S+LSG
Sbjct:  880 KVQEVLASTAVRGILMSLGLAIGLLTLMTTNWIVGLMAGATIACITVGVVGFIPLVGWKLGVLESLNLTLVVGLAVDYVVHLADGYVRSHNHFRGDKTRDALGSVGISVLSG 991
[Close]
BLAST of protein dispatched homolog 1 vs. Ensembl Nematostella
Match: EDO44540 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RVB1])

HSP 1 Score: 58.5362 bits (140), Expect = 3.370e-9
Identity = 57/170 (33.53%), Postives = 84/170 (49.41%), Query Frame = 3 
Query:  648 LIGSAIAGVLSGLIIS----FPIILMATLNFHTFLIIIIGTCLSTLSVT--SLIYVTGWNLGLLESINLTVVVGLTIDYLVHMGLAYN-SSQKEHRDERTEDMLEEMGVSILSGMXXXXXXXXXXXXXXXXXXXXXGVFVFATIFSAGIYSIIFLPCMFLVFGPSQGRGD 1136
            L  S  AG  S + IS    F ++L+ TLN    L  II T +  L++T  SL+ + GW L +LESI ++V VGL+ID+ +H G+AY  S  K+ RD R       +G +I     TT  +   +         Q GVF+   +F + IY+ +    M  + GP    G 
Sbjct:  638 LQASLSAGTFSSMSISVAIAFVVMLLTTLNIFISLYAII-TIVGILAITVGSLV-LLGWQLNILESIVMSVAVGLSIDFTMHYGVAYRLSPYKDRRDIRVRYSFVHIGSAIFMAALTTFITGLLMMPAIVLVYNQLGVFLMLVMFFSYIYATLAFQSMCALIGPINNFGQ 805
[Close]
BLAST of protein dispatched homolog 1 vs. Ensembl Nematostella
Match: EDO42868 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S0G1])

HSP 1 Score: 51.2174 bits (121), Expect = 7.443e-7
Identity = 34/136 (25.00%), Postives = 68/136 (50.00%), Query Frame = 3 
Query:  720 LNFHTFLIIIIGTCLSTLSVTSLIYVTGWNLGLLESINLTVVVGLTIDYLVHMGLAYNSSQKEHRDERTEDMLEEMGVSILSGMXXXX---XXXXXXXXXXXXXXXXXGVFVFATIFSAGIYSIIFLPCMFLVFGP 1118
             N    LI+     +   ++  L+Y+   +L  +  +NL + VG+++++  H+  A+  + +  + ER E+ L EMG S+LSG++ T             +   +F F ++V   +F A ++ ++FLP +    GP
Sbjct: 1120 FNLSIALIVTFTVAMIITNLLGLMYLWSISLNAISIVNLVMAVGISVEFCSHIARAFAVNTRNTKRERAEEALIEMGSSVLSGITLTKFGGIIVLAFAKSRIFEIFYFRMYVGIVLFGA-LHGLVFLPVLLSYVGP 1254
[Close]
BLAST of protein dispatched homolog 1 vs. Ensembl Medaka
Match: disp1 (dispatched RND transporter family member 1 [Source:NCBI gene;Acc:101161771])

HSP 1 Score: 67.0106 bits (162), Expect = 2.424e-11
Identity = 46/162 (28.40%), Postives = 78/162 (48.15%), Query Frame = 3 
Query:  654 GSAIAGVLSGLIISFPIILMATLNFHTFLIIIIGTCLSTLSVTSLIYVT-------GWNLGLLESINLTVVVGLTIDYLVHMGLAYNSSQKEHRDERTEDMLEEMGVSILSGMXXXXXXXXXXXXXXXXXXXXXGVFVFATIFSAGIYSIIFLPCMFLVFGP 1118
            G+ +A  LS + ++F ++L+ T N       II +  + LS+   I+VT       GW L +LES+ ++V VGL++D+ VH G+AY  + +  R+ +    L  MG +I     TT  +   +         Q G F+   +  +  ++  F  CM    GP
Sbjct:  820 GTLVAMALS-VAVAFSVMLLTTWN-------IIISLYAILSIAGTIFVTVGSLVLLGWELNVLESVTISVAVGLSVDFSVHYGVAYRLAPEPDREGKVIFSLSRMGSAIAMAAVTTFVAGAMMMPSTVLAYTQLGTFMMLIMCISWAFATFFFQCMCRCLGP 973
[Close]
BLAST of protein dispatched homolog 1 vs. Planmine SMEST
Match: SMESG000053118.1 (SMESG000053118.1)

HSP 1 Score: 306.99 bits (785), Expect = 1.270e-95
Identity = 171/186 (91.94%), Postives = 180/186 (96.77%), Query Frame = 3 
Query:  645 MLIGSAIAGVLSGLIISFPIILMATLNFHTFLIIIIGTCLSTLSVTSLIYVTGWNLGLLESINLTVVVGLTIDYLVHMGLAYNSSQKEHRDERTEDMLEEMGVSILSGMXXXXXXXXXXXXXXXXXXXXXGVFVFATIFSAGIYSIIFLPCMFLVFGPSQGRGDFHCDFYRCMPCFKIEKRSEKYK 1202
            +LIGSA+AG+LSGLIIS PI+  ATLN HTFLII+IGTCLSTLSVTSLIY+TGWNLGLLESINLTVVVGLTIDYLVHMGLAYNSSQK+HRDERTEDMLEEMGVSILSGMSTTLGSSFFLFFCQ+KFLFQFGVFVFATIFSAGIYS+IFLPCMFLVFGPSQGRGDFHCDFYRCMPC K EKRSEKYK
Sbjct:  705 LLIGSAVAGILSGLIISCPIVWFATLNVHTFLIILIGTCLSTLSVTSLIYITGWNLGLLESINLTVVVGLTIDYLVHMGLAYNSSQKKHRDERTEDMLEEMGVSILSGMSTTLGSSFFLFFCQTKFLFQFGVFVFATIFSAGIYSMIFLPCMFLVFGPSQGRGDFHCDFYRCMPCLKTEKRSEKYK 890

HSP 2 Score: 210.69 bits (535), Expect = 5.078e-60
Identity = 106/150 (70.67%), Postives = 118/150 (78.67%), Query Frame = 2 
Query:  305 NICDTLSKADKNLIIELSLFDGLEHINCLLYNMNDYFLTRFPTKNFQIPWKTSNFMELVSVMGPNFTAGPDFPYKFETALYYYLTDGFTFSDYGKYHLFPMNEKIQRMRQMKY---DAHWICYSRCIVRTYYFISNNFDGYSKFSYVFNN 745
            NICDTL  ADKNL  ELSLFDGLEHINCLLYNMNDY+L RFPTKNFQIPWKTSNFMELVSVMGPNFTAGPDFPYKFETALYYYLTDGFTFSDYGKY++F +N KIQR + M+Y     + +  S  +V    F      G+S+   VFN+
Sbjct:  521 NICDTLITADKNLKTELSLFDGLEHINCLLYNMNDYYLPRFPTKNFQIPWKTSNFMELVSVMGPNFTAGPDFPYKFETALYYYLTDGFTFSDYGKYYIFRINRKIQRTKPMRYGLLKGYSLNLSAILVNITLF--QKLSGFSEKKKVFNS 668
[Close]
BLAST of protein dispatched homolog 1 vs. Planmine SMEST
Match: SMESG000053118.1 (SMESG000053118.1)

HSP 1 Score: 306.605 bits (784), Expect = 3.301e-95
Identity = 171/186 (91.94%), Postives = 180/186 (96.77%), Query Frame = 3 
Query:  645 MLIGSAIAGVLSGLIISFPIILMATLNFHTFLIIIIGTCLSTLSVTSLIYVTGWNLGLLESINLTVVVGLTIDYLVHMGLAYNSSQKEHRDERTEDMLEEMGVSILSGMXXXXXXXXXXXXXXXXXXXXXGVFVFATIFSAGIYSIIFLPCMFLVFGPSQGRGDFHCDFYRCMPCFKIEKRSEKYK 1202
            +LIGSA+AG+LSGLIIS PI+  ATLN HTFLII+IGTCLSTLSVTSLIY+TGWNLGLLESINLTVVVGLTIDYLVHMGLAYNSSQK+HRDERTEDMLEEMGVSILSGMSTTLGSSFFLFFCQ+KFLFQFGVFVFATIFSAGIYS+IFLPCMFLVFGPSQGRGDFHCDFYRCMPC K EKRSEKYK
Sbjct:  747 LLIGSAVAGILSGLIISCPIVWFATLNVHTFLIILIGTCLSTLSVTSLIYITGWNLGLLESINLTVVVGLTIDYLVHMGLAYNSSQKKHRDERTEDMLEEMGVSILSGMSTTLGSSFFLFFCQTKFLFQFGVFVFATIFSAGIYSMIFLPCMFLVFGPSQGRGDFHCDFYRCMPCLKTEKRSEKYK 932

HSP 2 Score: 210.305 bits (534), Expect = 7.714e-60
Identity = 106/150 (70.67%), Postives = 118/150 (78.67%), Query Frame = 2 
Query:  305 NICDTLSKADKNLIIELSLFDGLEHINCLLYNMNDYFLTRFPTKNFQIPWKTSNFMELVSVMGPNFTAGPDFPYKFETALYYYLTDGFTFSDYGKYHLFPMNEKIQRMRQMKY---DAHWICYSRCIVRTYYFISNNFDGYSKFSYVFNN 745
            NICDTL  ADKNL  ELSLFDGLEHINCLLYNMNDY+L RFPTKNFQIPWKTSNFMELVSVMGPNFTAGPDFPYKFETALYYYLTDGFTFSDYGKY++F +N KIQR + M+Y     + +  S  +V    F      G+S+   VFN+
Sbjct:  563 NICDTLITADKNLKTELSLFDGLEHINCLLYNMNDYYLPRFPTKNFQIPWKTSNFMELVSVMGPNFTAGPDFPYKFETALYYYLTDGFTFSDYGKYYIFRINRKIQRTKPMRYGLLKGYSLNLSAILVNITLF--QKLSGFSEKKKVFNS 710
[Close]
BLAST of protein dispatched homolog 1 vs. Planmine SMEST
Match: SMESG000053318.1 (SMESG000053318.1)

HSP 1 Score: 223.016 bits (567), Expect = 5.840e-71
Identity = 129/181 (71.27%), Postives = 158/181 (87.29%), Query Frame = 3 
Query:  639 NTMLIGSAIAGVLSGLIISFPIILMATLNFHTFLIIIIGTCLSTLSVTSLIYVTGWNLGLLESINLTVVVGLTIDYLVHMGLAYNSSQKEHRDERTEDMLEEMGVSILSGMXXXXXXXXXXXXXXXXXXXXXGVFVFATIFSAGIYSIIFLPCMFLVFGPSQGRGDFHCDFYRCMPCFKIE 1181
              MLI +A+AG+LSG+++S PIIL AT N +TFLIIIIGT LSTLSVTSLI +TGWNLGLLES+NLT+VVG+TIDYLVHMGLAYN+S+KE ++ERT+DMLE MG+SILSGM+TTLGS+FFLFFC+++FLFQFG+F+FATI S+GIYS+IFLPCMFLVFGP   +GD  C F+R  P  K+ 
Sbjct:   21 QEMLINAALAGILSGILVSCPIILCATQNIYTFLIIIIGTGLSTLSVTSLISITGWNLGLLESVNLTIVVGMTIDYLVHMGLAYNNSEKEGKEERTQDMLENMGISILSGMATTLGSTFFLFFCKTRFLFQFGLFIFATILSSGIYSMIFLPCMFLVFGPKLKQGDCKCKFFRRPPFIKLR 201
[Close]
BLAST of protein dispatched homolog 1 vs. Planmine SMEST
Match: SMESG000053129.1 (SMESG000053129.1)

HSP 1 Score: 214.927 bits (546), Expect = 5.847e-68
Identity = 128/184 (69.57%), Postives = 156/184 (84.78%), Query Frame = 3 
Query:  645 MLIGSAIAGVLSGLIISFPIILMATLNFHTFLIIIIGTCLSTLSVTSLIYVTGWNLGLLESINLTVVVGLTIDYLVHMGLAYNSSQKEHRDERTEDMLEEMGVSILSGMXXXXXXXXXXXXXXXXXXXXXGVFVFATIFSAGIYSIIFLPCMFLVFGPSQGRGDFHCDFYRCMPCFKIEKRSEK 1196
            MLI +AIAG+ SGLII+ PI+  ATLN  TF II++GTCLSTL+VTS+IY+ GWNLGLLESINLTVVVGLTIDYLVHMGLAY SS+KE +++R ++ML EMG+SILSGM+TTLGSSFFL FCQ+KFLFQFG+FVF TIFSAG+YS+IFLPC+FL FG   G+ DF  +FYR +P FK +   ++
Sbjct:    1 MLIDAAIAGITSGLIIACPIVFCATLNIVTFSIIMLGTCLSTLTVTSMIYIIGWNLGLLESINLTVVVGLTIDYLVHMGLAYKSSEKESKEDRVQEMLGEMGISILSGMATTLGSSFFLLFCQTKFLFQFGIFVFITIFSAGVYSMIFLPCIFLTFGARYGQYDFGRNFYRRIPFFKNKVNDDQ 184
[Close]
BLAST of protein dispatched homolog 1 vs. Planmine SMEST
Match: SMESG000053240.1 (SMESG000053240.1)

HSP 1 Score: 203.756 bits (517), Expect = 4.759e-62
Identity = 122/160 (76.25%), Postives = 141/160 (88.12%), Query Frame = 3 
Query:  645 MLIGSAIAGVLSGLIISFPIILMATLNFHTFLIIIIGTCLSTLSVTSLIYVTGWNLGLLESINLTVVVGLTIDYLVHMGLAYNSSQKEHRDERTEDMLEEMGVSILSGMXXXXXXXXXXXXXXXXXXXXXGVFVFATIFSAGIYSIIFLPCMFLVFGPSQ 1124
            MLI +A+AGV  GL+IS PIIL+AT N  TFLII++GTCLS LSVTS++ + GWNLGLLESINLT++VGLTIDYLVHMGLAYNSS+K+ R+ERT +MLE+MGVSILSGM+TTLGSSFFLFFC + FLFQFGVFVF TIFSAGIYS+IFLPC FL FGP  
Sbjct:  152 MLINAALAGVTLGLLISSPIILLATRNVFTFLIIMLGTCLSALSVTSMVSIVGWNLGLLESINLTLIVGLTIDYLVHMGLAYNSSKKKSREERTVEMLEDMGVSILSGMATTLGSSFFLFFCTTMFLFQFGVFVFVTIFSAGIYSMIFLPCFFLAFGPQN 311

HSP 2 Score: 125.561 bits (314), Expect = 2.029e-32
Identity = 56/83 (67.47%), Postives = 69/83 (83.13%), Query Frame = 2 
Query:  401 MNDYFLTRFPTKNFQIPWKTSNFMELVSVMGPNFTAGPDFPYKFETALYYYLTDGFTFSDYGKYHLFPMNEKIQRMRQMKYDA 649
            M++Y++ +FPTKNFQIPWKTSNF+EL   +  NFTAGPDFPYKFETALYY+L+D  TFS YGKYH++P NEKI + R+ KY A
Sbjct:    1 MDEYYVQKFPTKNFQIPWKTSNFLELAP-LALNFTAGPDFPYKFETALYYFLSDSLTFSSYGKYHIYPRNEKIAKYRRKKYGA 82
The following BLAST results are available for this feature:
BLAST of protein dispatched homolog 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 1
Match NameE-valueIdentityDescription
DISP11.060e-926.45dispatched RND transporter family member 1 [Source... [more]
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BLAST of protein dispatched homolog 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of protein dispatched homolog 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of protein dispatched homolog 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
disp12.452e-1227.74dispatched homolog 1 (Drosophila) [Source:NCBI gen... [more]
disp12.452e-1227.74dispatched homolog 1 (Drosophila) [Source:NCBI gen... [more]
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BLAST of protein dispatched homolog 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 1
Match NameE-valueIdentityDescription
DISP12.897e-728.22dispatched RND transporter family member 1 [Source... [more]
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BLAST of protein dispatched homolog 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 3
Match NameE-valueIdentityDescription
Disp12.074e-1026.45dispatched RND transporter family member 1 [Source... [more]
Disp12.074e-1026.45dispatched RND transporter family member 1 [Source... [more]
Disp12.074e-1026.45dispatched RND transporter family member 1 [Source... [more]
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BLAST of protein dispatched homolog 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 3
Match NameE-valueIdentityDescription
sp|Q6R5J2|DISP1_DANRE1.851e-1127.74Protein dispatched homolog 1 OS=Danio rerio OX=795... [more]
sp|Q3TDN0|DISP1_MOUSE1.451e-926.45Protein dispatched homolog 1 OS=Mus musculus OX=10... [more]
sp|Q96F81|DISP1_HUMAN5.089e-926.45Protein dispatched homolog 1 OS=Homo sapiens OX=96... [more]
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BLAST of protein dispatched homolog 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1S3HIR21.428e-1937.20uncharacterized protein LOC106155638 OS=Lingula un... [more]
A0A1S3ID809.307e-1843.52protein dispatched homolog 1 OS=Lingula unguis OX=... [more]
K1RCQ51.033e-1739.44Dispatched-like protein 1 OS=Crassostrea gigas OX=... [more]
A0A210R3521.914e-1737.84Protein dispatched-like 1 OS=Mizuhopecten yessoens... [more]
R7U1472.361e-1742.68SSD domain-containing protein OS=Capitella teleta ... [more]
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BLAST of protein dispatched homolog 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
disp19.112e-1226.63dispatched RND transporter family member 1 [Source... [more]
disp19.124e-1226.63dispatched RND transporter family member 1 [Source... [more]
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BLAST of protein dispatched homolog 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
disp13.354e-728.89dispatched homolog 1 (Drosophila) [Source:NCBI gen... [more]
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BLAST of protein dispatched homolog 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of protein dispatched homolog 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 4
Match NameE-valueIdentityDescription
EDO468004.414e-1437.96Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO468012.135e-1336.61Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO445403.370e-933.53Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO428687.443e-725.00Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of protein dispatched homolog 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
disp12.424e-1128.40dispatched RND transporter family member 1 [Source... [more]
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BLAST of protein dispatched homolog 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000053118.11.270e-9591.94SMESG000053118.1[more]
SMESG000053118.13.301e-9591.94SMESG000053118.1[more]
SMESG000053318.15.840e-7171.27SMESG000053318.1[more]
SMESG000053129.15.847e-6869.57SMESG000053129.1[more]
SMESG000053240.14.759e-6276.25SMESG000053240.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30019084 ID=SMED30019084|Name=protein dispatched homolog 1|organism=Schmidtea mediterranea sexual|type=transcript|length=1317bp
TCCGATCTGAAAAATCAGTGCAAAACATTGAAAATCGTAAAACATCAATT
TTTTTAGTTTGTCGGTAACCATCGGATCCTTATGGTTGCTGTGATAACGT
GACTTACATAAAAATATTAATTGACCGTACATAAATATCCTCAATTTTTT
TAACGTTTTAGAAAAATCCTCAGGAGGGGGTGTCCTGGAGGCGACAAATC
CTACTACTAAGAATGCTGGGTTTTTTCGTTAAATTTGAATTAATAAATTT
TCTGAATTTTGTGACTTTACTTTTTATATTAAATTGAAGTTTAATTAACT
TTAGAATATTTGTGACACTCTTAGTAAAGCTGATAAAAATTTAATAATTG
AATTATCGTTATTCGACGGACTTGAACATATAAATTGTTTATTATATAAT
ATGAATGATTATTTCCTCACAAGATTTCCAACAAAAAACTTTCAAATACC
TTGGAAAACCTCTAATTTTATGGAACTTGTTAGTGTCATGGGACCAAATT
TTACAGCAGGTCCTGATTTCCCATATAAATTTGAGACTGCATTATACTAC
TATCTAACTGATGGATTTACGTTTTCTGATTACGGTAAATATCATTTATT
CCCAATGAATGAAAAAATTCAAAGGATGAGGCAAATGAAATACGATGCTC
ATTGGATCTGCTATAGCCGGTGTATTGTCAGGACTTATTATTTCATTTCC
AATAATTTTGATGGCTACTCTAAATTTTCATACGTTTTTAATAATAATCA
TTGGGACATGTTTAAGTACGCTGTCGGTTACATCCTTAATTTATGTAACT
GGTTGGAATTTAGGGTTGTTAGAAAGCATAAATTTGACAGTTGTCGTTGG
ATTGACTATTGACTATCTTGTCCACATGGGACTTGCATATAACAGTTCAC
AAAAAGAACATAGAGACGAAAGAACCGAAGACATGCTTGAAGAAATGGGA
GTATCTATATTATCTGGAATGTCCACGACTTTGGGCTCGTCATTTTTCCT
ATTTTTTTGTCAATCTAAATTTTTATTTCAATTCGGCGTTTTTGTTTTTG
CCACAATTTTCAGTGCTGGAATTTATTCAATTATATTTTTACCATGCATG
TTTCTAGTATTCGGTCCGAGTCAAGGACGTGGTGACTTTCACTGTGATTT
TTATCGTTGTATGCCTTGTTTCAAGATCGAGAAAAGAAGCGAGAAATATA
AATAAATATTATAACTAACTTCTGAATTTGTTTCTTTTAAATTTTGGTGT
TATAGAAAGAATTGACAATTTATCATACAATATAATAAATAATTCTTTTC
TTATTTTTGTGAACCGA
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protein sequence of SMED30019084-orf-1

>SMED30019084-orf-1 ID=SMED30019084-orf-1|Name=SMED30019084-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=187bp
MLIGSAIAGVLSGLIISFPIILMATLNFHTFLIIIIGTCLSTLSVTSLIY
VTGWNLGLLESINLTVVVGLTIDYLVHMGLAYNSSQKEHRDERTEDMLEE
MGVSILSGMSTTLGSSFFLFFCQSKFLFQFGVFVFATIFSAGIYSIIFLP
CMFLVFGPSQGRGDFHCDFYRCMPCFKIEKRSEKYK*
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protein sequence of SMED30019084-orf-2

>SMED30019084-orf-2 ID=SMED30019084-orf-2|Name=SMED30019084-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=154bp
MNDYFLTRFPTKNFQIPWKTSNFMELVSVMGPNFTAGPDFPYKFETALYY
YLTDGFTFSDYGKYHLFPMNEKIQRMRQMKYDAHWICYSRCIVRTYYFIS
NNFDGYSKFSYVFNNNHWDMFKYAVGYILNLCNWLEFRVVRKHKFDSCRW
IDY*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR003392Ptc/Disp
Vocabulary: cellular component
TermDefinition
GO:0016021integral component of membrane
GO:0016020membrane
Vocabulary: biological process
TermDefinition
GO:0007224smoothened signaling pathway
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableGENE3DG3DSA:1.20.1640.10coord: 3..166
e-value: 1.2E-8
score: 36.5
NoneNo IPR availablePANTHERPTHR45951FAMILY NOT NAMEDcoord: 6..166
NoneNo IPR availableSUPERFAMILYSSF82866Multidrug efflux transporter AcrB transmembrane domaincoord: 4..158
NoneNo IPR availableTMHMMTMhelixcoord: 31..53
NoneNo IPR availableTMHMMTMhelixcoord: 5..27
NoneNo IPR availableTMHMMTMhelixcoord: 128..150
NoneNo IPR availableTMHMMTMhelixcoord: 60..82
NoneNo IPR availableTMHMMTMhelixcoord: 102..121
IPR003392Protein patched/dispatchedPFAMPF02460Patchedcoord: 5..157
e-value: 7.4E-5
score: 21.0