SD2
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30019046 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 7
Homology
BLAST of SD2 vs. Ensembl Human
Match: TEAD3 (TEA domain transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:11716]) HSP 1 Score: 337.806 bits (865), Expect = 9.939e-110 Identity = 198/470 (42.13%), Postives = 279/470 (59.36%), Query Frame = 1
Query: 130 EAEGVWSPDIENSFNEALQLYPPCGRRKIVLSEEGKMYGRNELIARYIKMQTGKSRSRKQVSSHIQVLARRKSKEIQNQIQ----EKHTREQARQQLANMSSAQIVSDFKIKENLSLCNDNRNKSPKFVDNNINSFSNTQGISRFSSI-----HHPTPLVANSKLLDTSSFLLRPNQIPPIMACTNTHNMYLKNDSPNDLISHNHTPIP-AMWNVPHMXXXXXXXXXXXXXGPHLYVGRSIATPKMRLLELSVFVEAKEYPVKIEKGFGMKNYCKHVFAHLNSTESSLGHPFLEHIEISQIWDKYPET-DGLKEYFERGPQDAFFMVKFWIDMNFDVLPQWNQLSTIIFEGV-------ENVKSKLSTKICSFGRQVLERIEEQSPILENGISIYRFENVPMCDYMRKFIIKLSSLKEHSLMNSVLENFTILQTVTNAFTGEILLCIAFAMEVSISDQGSQYHIYKLIRN 1485
+AEGVWSPDIE SF EAL +YPPCGRRKI+LS+EGKMYGRNELIARYIK++TGK+R+RKQVSSH+QVLARRKS+EIQ++++ ++ ++++A Q +A+MSSAQIVS ++ N+ P + + S S SRF S P P + K ++ ++P +PP ++ P+P A +VP ++ R+IA+ ++RLLE S F+E + P Y KH+F H+ T + P LE +++ QI+DK+PE GLKE +E+GP +AFF+VKFW D+N + Q F GV +++ +STK+CSFG+QV+E++E + LENG +YR PMC+YM FI KL L E +MNSVLENFTILQ VT+ + E LL IAF EVS S+ G+Q+H+YKL+++
Sbjct: 30 DAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHLQVLARRKSREIQSKLKAMNLDQVSKDKALQSMASMSSAQIVSASVLQ--------NKFSPPSPLPQAVFSTS-----SRFWSSPPLLGQQPGP-SQDIKPFAQPAYPIQPP-LPPTLSSYEPL-----------------APLPSAAASVP------------------VWQDRTIASSRLRLLEYSAFMEVQRDP---------DTYSKHLFVHIGQTNPAFSDPPLEAVDVRQIYDKFPEKKGGLKELYEKGPPNAFFLVKFWADLNSTI-----QEGPGAFYGVSSQYSSADSMTISVSTKVCSFGKQVVEKVETEYARLENGRFVYRIHRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTSRDSQETLLVIAFVFEVSTSEHGAQHHVYKLVKD 435
BLAST of SD2 vs. Ensembl Human
Match: TEAD3 (TEA domain transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:11716]) HSP 1 Score: 331.257 bits (848), Expect = 3.120e-107 Identity = 197/470 (41.91%), Postives = 275/470 (58.51%), Query Frame = 1
Query: 130 EAEGVWSPDIENSFNEALQLYPPCGRRKIVLSEEGKMYGRNELIARYIKMQTGKSRSRKQVSSHIQVLARRKSKEIQNQIQ----EKHTREQARQQLANMSSAQIVSDFKIKENLSLCNDNRNKSPKFVDNNINSFSNTQGISRFSSI-----HHPTPLVANSKLLDTSSFLLRPNQIPPIMACTNTHNMYLKNDSPNDLISHNHTPIP-AMWNVPHMXXXXXXXXXXXXXGPHLYVGRSIATPKMRLLELSVFVEAKEYPVKIEKGFGMKNYCKHVFAHLNSTESSLGHPFLEHIEISQIWDKYPET-DGLKEYFERGPQDAFFMVKFWIDMNFDVLPQWNQLSTIIFEGV-------ENVKSKLSTKICSFGRQVLERIEEQSPILENGISIYRFENVPMCDYMRKFIIKLSSLKEHSLMNSVLENFTILQTVTNAFTGEILLCIAFAMEVSISDQGSQYHIYKLIRN 1485
+AEGVWSPDIE SF EAL +YPPCGRRKI+LS+EGKMYGRNELIARYIK++TGK+R+RKQVSSHIQVLAR+K +E Q I+ ++ ++++A Q +A+MSSAQIVS ++ N+ P + + S S SRF S P P + K ++ ++P +PP ++ P+P A +VP ++ R+IA+ ++RLLE S F+E + P Y KH+F H+ T + P LE +++ QI+DK+PE GLKE +E+GP +AFF+VKFW D+N + Q F GV +++ +STK+CSFG+QV+E++E + LENG +YR PMC+YM FI KL L E +MNSVLENFTILQ VT+ + E LL IAF EVS S+ G+Q+H+YKL+++
Sbjct: 30 DAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARKKVREYQVGIKAMNLDQVSKDKALQSMASMSSAQIVSASVLQ--------NKFSPPSPLPQAVFSTS-----SRFWSSPPLLGQQPGP-SQDIKPFAQPAYPIQPP-LPPTLSSYEPL-----------------APLPSAAASVP------------------VWQDRTIASSRLRLLEYSAFMEVQRDP---------DTYSKHLFVHIGQTNPAFSDPPLEAVDVRQIYDKFPEKKGGLKELYEKGPPNAFFLVKFWADLNSTI-----QEGPGAFYGVSSQYSSADSMTISVSTKVCSFGKQVVEKVETEYARLENGRFVYRIHRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTSRDSQETLLVIAFVFEVSTSEHGAQHHVYKLVKD 435
BLAST of SD2 vs. Ensembl Human
Match: TEAD2 (TEA domain transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:11715]) HSP 1 Score: 269.24 bits (687), Expect = 5.063e-83 Identity = 173/467 (37.04%), Postives = 248/467 (53.10%), Query Frame = 1
Query: 136 EGVWSPDIENSFNEALQLYPPCGRRKIVLSEEGKMYGRNELIARYIKMQTGKSRSRKQVSSHIQVLARRKSKEIQNQIQEKHTREQARQQLANMSSAQIVSDFKIKENLSLCNDNRNKSPKFVDNNINSFSNTQGISRFS--SIHHPTPLVANSKLLDTSSFLLRPNQIPPIMACTNTHNMYLKNDSPNDL-ISHNHTPIPAMWNVPHMXXXXXXXXXXXXXGPHLYVGRSIATPKMRLLELSVFVEAKEYPVKIEKGFGMKNYCKHVFAHLNSTESSLGHPFLEHIEISQIWDKYPET-DGLKEYFERGPQDAFFMVKFWIDMNFDVLPQWNQLSTII-------------FEGVENVKSKLSTKICSFGRQVLERIEEQSPILENGISIYRFENVPMCDYMRKFIIKLSSLKEHSLMNSVLENFTILQTVTNAFTGEILLCIAFAMEVSISDQGSQYHIYKLIRN 1485
EGVWSPDIE SF EAL +YPPCGRRKI+LS+EGKMYGRNELIARYIK++TGK+ R K++ + IQ LA S +I S K +L D +K F + + S+ Q IS S + PT A+ S P +P + + T P L ++ T +P + P S + R + T +++L+E S FVE + + +Y +H+F H++ S G P LE +++ QI+DK+PE GL+E ++RGP AFF+VKFW D+N+ P + +E +E++ S+K+CSFG+QV+E++E + LE+G +YR PMC+Y+ F+ KL L E +MNSVLENFTILQ VTN T E+LLC A+ EVS S++G+Q+HIY+L+R+
Sbjct: 42 EGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKT---------------RTRKQVSSHIQ----------VLARRKSREIQSKLK-----ALNVDQVSKDKAF--QTMATMSSAQLISAPSLQAKLGPTGPQASELFQFWSGGSGPPWNVPDVKPFSQT---------PFTLSLTPPSTDLPG-YEPPQALSPLPPPTPSPPA----WQARGLGTARLQLVEFSAFVEPPD---------AVDSYQRHLFVHISQHCPSPGAPPLESVDVRQIYDKFPEKKGGLRELYDRGPPHAFFLVKFWADLNWG--PSGEEAGAGGSISSGGFYGVSSQYESLEHMTLTCSSKVCSFGKQVVEKVETERAQLEDGRFVYRLLRSPMCEYLVNFLHKLRQLPERYMMNSVLENFTILQVVTNRDTQELLLCTAYVFEVSTSERGAQHHIYRLVRD 451
BLAST of SD2 vs. Ensembl Human
Match: TEAD2 (TEA domain transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:11715]) HSP 1 Score: 269.24 bits (687), Expect = 5.063e-83 Identity = 173/467 (37.04%), Postives = 248/467 (53.10%), Query Frame = 1
Query: 136 EGVWSPDIENSFNEALQLYPPCGRRKIVLSEEGKMYGRNELIARYIKMQTGKSRSRKQVSSHIQVLARRKSKEIQNQIQEKHTREQARQQLANMSSAQIVSDFKIKENLSLCNDNRNKSPKFVDNNINSFSNTQGISRFS--SIHHPTPLVANSKLLDTSSFLLRPNQIPPIMACTNTHNMYLKNDSPNDL-ISHNHTPIPAMWNVPHMXXXXXXXXXXXXXGPHLYVGRSIATPKMRLLELSVFVEAKEYPVKIEKGFGMKNYCKHVFAHLNSTESSLGHPFLEHIEISQIWDKYPET-DGLKEYFERGPQDAFFMVKFWIDMNFDVLPQWNQLSTII-------------FEGVENVKSKLSTKICSFGRQVLERIEEQSPILENGISIYRFENVPMCDYMRKFIIKLSSLKEHSLMNSVLENFTILQTVTNAFTGEILLCIAFAMEVSISDQGSQYHIYKLIRN 1485
EGVWSPDIE SF EAL +YPPCGRRKI+LS+EGKMYGRNELIARYIK++TGK+ R K++ + IQ LA S +I S K +L D +K F + + S+ Q IS S + PT A+ S P +P + + T P L ++ T +P + P S + R + T +++L+E S FVE + + +Y +H+F H++ S G P LE +++ QI+DK+PE GL+E ++RGP AFF+VKFW D+N+ P + +E +E++ S+K+CSFG+QV+E++E + LE+G +YR PMC+Y+ F+ KL L E +MNSVLENFTILQ VTN T E+LLC A+ EVS S++G+Q+HIY+L+R+
Sbjct: 42 EGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKT---------------RTRKQVSSHIQ----------VLARRKSREIQSKLK-----ALNVDQVSKDKAF--QTMATMSSAQLISAPSLQAKLGPTGPQASELFQFWSGGSGPPWNVPDVKPFSQT---------PFTLSLTPPSTDLPG-YEPPQALSPLPPPTPSPPA----WQARGLGTARLQLVEFSAFVEPPD---------AVDSYQRHLFVHISQHCPSPGAPPLESVDVRQIYDKFPEKKGGLRELYDRGPPHAFFLVKFWADLNWG--PSGEEAGAGGSISSGGFYGVSSQYESLEHMTLTCSSKVCSFGKQVVEKVETERAQLEDGRFVYRLLRSPMCEYLVNFLHKLRQLPERYMMNSVLENFTILQVVTNRDTQELLLCTAYVFEVSTSERGAQHHIYRLVRD 451
BLAST of SD2 vs. Ensembl Human
Match: TEAD2 (TEA domain transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:11715]) HSP 1 Score: 268.855 bits (686), Expect = 5.136e-83 Identity = 170/474 (35.86%), Postives = 246/474 (51.90%), Query Frame = 1
Query: 136 EGVWSPDIENSFNEALQLYPPCGRRKIVLSEEGKMYGRNELIARYIKMQTGKSRSRKQVSSHIQVLARRKSKEIQNQIQEKHTREQARQQLANMSSAQIVSDFKIKENLSLCNDNRNKSPKFVDNNINSFSNTQGISRFSSIHHPTPLVANSKLLDTSSFLLRPNQIPPIMACTNTHNMYLKNDSPN----DLISHNHTPI-----PAMWNVP-HMXXXXXXXXXXXXXGPHLYVGRSIATPKMRLLELSVFVEAKEYPVKIEKGFGMKNYCKHVFAHLNSTESSLGHPFLEHIEISQIWDKYPET-DGLKEYFERGPQDAFFMVKFWIDMNFDVLPQWNQLSTII-------------FEGVENVKSKLSTKICSFGRQVLERIEEQSPILENGISIYRFENVPMCDYMRKFIIKLSSLKEHSLMNSVLENFTILQTVTNAFTGEILLCIAFAMEVSISDQGSQYHIYKLIRN 1485
EGVWSPDIE SF EAL +YPPCGRRKI+LS+EGKMYGRNELIARYIK++TGK+ R K++ + IQ LA S +I S K D +K F + + S+ Q IS S +KL T P ++ + + P D+ + TP P ++P + + P + R + T +++L+E S FVE + + +Y +H+F H++ S G P LE +++ QI+DK+PE GL+E ++RGP AFF+VKFW D+N+ P + +E +E++ S+K+CSFG+QV+E++E + LE+G +YR PMC+Y+ F+ KL L E +MNSVLENFTILQ VTN T E+LLC A+ EVS S++G+Q+HIY+L+R+
Sbjct: 42 EGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKT---------------RTRKQVSSHIQ----------VLARRKSREIQSKLK---------DQVSKDKAF--QTMATMSSAQLISAPS---------LQAKLGPTG---------PQVVQASELFQFWSGGSGPPWNVPDVKPFSQTPFTLSLTPPSTDLPGYEPPQALSPLPPPTPSPPAWQARGLGTARLQLVEFSAFVEPPD---------AVDSYQRHLFVHISQHCPSPGAPPLESVDVRQIYDKFPEKKGGLRELYDRGPPHAFFLVKFWADLNWG--PSGEEAGAGGSISSGGFYGVSSQYESLEHMTLTCSSKVCSFGKQVVEKVETERAQLEDGRFVYRLLRSPMCEYLVNFLHKLRQLPERYMMNSVLENFTILQVVTNRDTQELLLCTAYVFEVSTSERGAQHHIYRLVRD 450
BLAST of SD2 vs. Ensembl Celegans
Match: egl-44 (Transcription enhancer factor-like protein egl-44 [Source:UniProtKB/Swiss-Prot;Acc:Q19849]) HSP 1 Score: 211.075 bits (536), Expect = 1.077e-61 Identity = 157/462 (33.98%), Postives = 233/462 (50.43%), Query Frame = 1
Query: 118 DESKEAEGVWSPDIENSFNEALQLYPPCGRRKIVLSEEGKMYGRNELIARYIKMQTGKSRSRKQVSSHIQVLARRKSKEIQNQIQEKHTREQARQQLA-NMSSAQIVSDFKIKENLSLCNDNRNKSPKFV-----DNNINSFSNTQGISRFSSIHHPTPLVANSKLLDTSSFLLRPNQIPPIMACTNTHNMYLKNDSPNDLISHNHTPIPAMWNVPHMXXXXXXXXXXXXXGPHLYVGRSIATPKMRLLELSVFVEAKEYPVKIEKGFGMKNYCKHVFAHLNSTESSLGHPFLEHIEISQIWDKYPETDGLKEYFERG-PQDAFFMVKFWIDMNFDVLPQWNQLSTIIF-EGVENVKSKLSTKICSFGRQVLERIEEQSPILENGISIYRFENVPMCDYMRKFIIKLSSLKEHSLMNSVLENFTILQTVTNAFTGEILLCIAFAMEVSISDQGSQYHIYKLI 1479
D S +AEGVWS DI+ +F EAL +YPPCGRRKI++S+EGKMYGRNELIARYIK++ GK+R+RKQVSSHIQVLA ++K EQA++++ ++++ I S + KSP V + + + S +SSI S+ L S L Q P + + + + SP+ +S + + + + IA+ ++ L S +V+ + ++ E L E++L + I+IS ++KYP+ L+E FE+ +D FF+ K W ++N Q Q + F E + K+ST CSFG Q +E+IE+ PI +G + N PMCDYM KFI +L L MN+VLENFT+LQ VTN+ T E+L+ + F EVS + S +Y+LI
Sbjct: 28 DLSGDAEGVWSIDIDQAFQEALAIYPPCGRRKIIISDEGKMYGRNELIARYIKLRCGKTRTRKQVSSHIQVLA-----------RKKLRDEQAKKKVPFHLNTGDIPSLLQ-----QASPPGGVKSPSAVVFPPVSAAVAAITEISPQSSYSSIVPKVETDQISQQLFKSLPLWSFQQTPGLPIGMDLSQLVFQQSSPDKTVSPVKSEV-------------------------VEETKPIASSQLTLHSFSAYVKCNKTSLRTE---------------LVKIENTLEK---DDIDISVFYEKYPKL--LRELFEKSEKKDVFFLAKCWANINVSDDVQNCQYAVDSFYSSREKFQLKVSTMACSFGNQAVEKIEQYFPIEFDGSYSFILNNSPMCDYMVKFIAELKKLNVIETMNNVLENFTVLQIVTNSETDELLMVLCFVFEVSQEPEPS-CSVYRLI 427
BLAST of SD2 vs. Ensembl Celegans
Match: egl-44 (Transcription enhancer factor-like protein egl-44 [Source:UniProtKB/Swiss-Prot;Acc:Q19849]) HSP 1 Score: 211.075 bits (536), Expect = 3.675e-61 Identity = 157/462 (33.98%), Postives = 233/462 (50.43%), Query Frame = 1
Query: 118 DESKEAEGVWSPDIENSFNEALQLYPPCGRRKIVLSEEGKMYGRNELIARYIKMQTGKSRSRKQVSSHIQVLARRKSKEIQNQIQEKHTREQARQQLA-NMSSAQIVSDFKIKENLSLCNDNRNKSPKFV-----DNNINSFSNTQGISRFSSIHHPTPLVANSKLLDTSSFLLRPNQIPPIMACTNTHNMYLKNDSPNDLISHNHTPIPAMWNVPHMXXXXXXXXXXXXXGPHLYVGRSIATPKMRLLELSVFVEAKEYPVKIEKGFGMKNYCKHVFAHLNSTESSLGHPFLEHIEISQIWDKYPETDGLKEYFERG-PQDAFFMVKFWIDMNFDVLPQWNQLSTIIF-EGVENVKSKLSTKICSFGRQVLERIEEQSPILENGISIYRFENVPMCDYMRKFIIKLSSLKEHSLMNSVLENFTILQTVTNAFTGEILLCIAFAMEVSISDQGSQYHIYKLI 1479
D S +AEGVWS DI+ +F EAL +YPPCGRRKI++S+EGKMYGRNELIARYIK++ GK+R+RKQVSSHIQVLA ++K EQA++++ ++++ I S + KSP V + + + S +SSI S+ L S L Q P + + + + SP+ +S + + + + IA+ ++ L S +V+ + ++ E L E++L + I+IS ++KYP+ L+E FE+ +D FF+ K W ++N Q Q + F E + K+ST CSFG Q +E+IE+ PI +G + N PMCDYM KFI +L L MN+VLENFT+LQ VTN+ T E+L+ + F EVS + S +Y+LI
Sbjct: 71 DLSGDAEGVWSIDIDQAFQEALAIYPPCGRRKIIISDEGKMYGRNELIARYIKLRCGKTRTRKQVSSHIQVLA-----------RKKLRDEQAKKKVPFHLNTGDIPSLLQ-----QASPPGGVKSPSAVVFPPVSAAVAAITEISPQSSYSSIVPKVETDQISQQLFKSLPLWSFQQTPGLPIGMDLSQLVFQQSSPDKTVSPVKSEV-------------------------VEETKPIASSQLTLHSFSAYVKCNKTSLRTE---------------LVKIENTLEK---DDIDISVFYEKYPKL--LRELFEKSEKKDVFFLAKCWANINVSDDVQNCQYAVDSFYSSREKFQLKVSTMACSFGNQAVEKIEQYFPIEFDGSYSFILNNSPMCDYMVKFIAELKKLNVIETMNNVLENFTVLQIVTNSETDELLMVLCFVFEVSQEPEPS-CSVYRLI 470
BLAST of SD2 vs. Ensembl Celegans
Match: egl-44 (Transcription enhancer factor-like protein egl-44 [Source:UniProtKB/Swiss-Prot;Acc:Q19849]) HSP 1 Score: 211.075 bits (536), Expect = 4.127e-61 Identity = 157/462 (33.98%), Postives = 233/462 (50.43%), Query Frame = 1
Query: 118 DESKEAEGVWSPDIENSFNEALQLYPPCGRRKIVLSEEGKMYGRNELIARYIKMQTGKSRSRKQVSSHIQVLARRKSKEIQNQIQEKHTREQARQQLA-NMSSAQIVSDFKIKENLSLCNDNRNKSPKFV-----DNNINSFSNTQGISRFSSIHHPTPLVANSKLLDTSSFLLRPNQIPPIMACTNTHNMYLKNDSPNDLISHNHTPIPAMWNVPHMXXXXXXXXXXXXXGPHLYVGRSIATPKMRLLELSVFVEAKEYPVKIEKGFGMKNYCKHVFAHLNSTESSLGHPFLEHIEISQIWDKYPETDGLKEYFERG-PQDAFFMVKFWIDMNFDVLPQWNQLSTIIF-EGVENVKSKLSTKICSFGRQVLERIEEQSPILENGISIYRFENVPMCDYMRKFIIKLSSLKEHSLMNSVLENFTILQTVTNAFTGEILLCIAFAMEVSISDQGSQYHIYKLI 1479
D S +AEGVWS DI+ +F EAL +YPPCGRRKI++S+EGKMYGRNELIARYIK++ GK+R+RKQVSSHIQVLA ++K EQA++++ ++++ I S + KSP V + + + S +SSI S+ L S L Q P + + + + SP+ +S + + + + IA+ ++ L S +V+ + ++ E L E++L + I+IS ++KYP+ L+E FE+ +D FF+ K W ++N Q Q + F E + K+ST CSFG Q +E+IE+ PI +G + N PMCDYM KFI +L L MN+VLENFT+LQ VTN+ T E+L+ + F EVS + S +Y+LI
Sbjct: 86 DLSGDAEGVWSIDIDQAFQEALAIYPPCGRRKIIISDEGKMYGRNELIARYIKLRCGKTRTRKQVSSHIQVLA-----------RKKLRDEQAKKKVPFHLNTGDIPSLLQ-----QASPPGGVKSPSAVVFPPVSAAVAAITEISPQSSYSSIVPKVETDQISQQLFKSLPLWSFQQTPGLPIGMDLSQLVFQQSSPDKTVSPVKSEV-------------------------VEETKPIASSQLTLHSFSAYVKCNKTSLRTE---------------LVKIENTLEK---DDIDISVFYEKYPKL--LRELFEKSEKKDVFFLAKCWANINVSDDVQNCQYAVDSFYSSREKFQLKVSTMACSFGNQAVEKIEQYFPIEFDGSYSFILNNSPMCDYMVKFIAELKKLNVIETMNNVLENFTVLQIVTNSETDELLMVLCFVFEVSQEPEPS-CSVYRLI 485
BLAST of SD2 vs. Ensembl Celegans
Match: egl-44 (Transcription enhancer factor-like protein egl-44 [Source:UniProtKB/Swiss-Prot;Acc:Q19849]) HSP 1 Score: 211.075 bits (536), Expect = 5.330e-61 Identity = 157/462 (33.98%), Postives = 233/462 (50.43%), Query Frame = 1
Query: 118 DESKEAEGVWSPDIENSFNEALQLYPPCGRRKIVLSEEGKMYGRNELIARYIKMQTGKSRSRKQVSSHIQVLARRKSKEIQNQIQEKHTREQARQQLA-NMSSAQIVSDFKIKENLSLCNDNRNKSPKFV-----DNNINSFSNTQGISRFSSIHHPTPLVANSKLLDTSSFLLRPNQIPPIMACTNTHNMYLKNDSPNDLISHNHTPIPAMWNVPHMXXXXXXXXXXXXXGPHLYVGRSIATPKMRLLELSVFVEAKEYPVKIEKGFGMKNYCKHVFAHLNSTESSLGHPFLEHIEISQIWDKYPETDGLKEYFERG-PQDAFFMVKFWIDMNFDVLPQWNQLSTIIF-EGVENVKSKLSTKICSFGRQVLERIEEQSPILENGISIYRFENVPMCDYMRKFIIKLSSLKEHSLMNSVLENFTILQTVTNAFTGEILLCIAFAMEVSISDQGSQYHIYKLI 1479
D S +AEGVWS DI+ +F EAL +YPPCGRRKI++S+EGKMYGRNELIARYIK++ GK+R+RKQVSSHIQVLA ++K EQA++++ ++++ I S + KSP V + + + S +SSI S+ L S L Q P + + + + SP+ +S + + + + IA+ ++ L S +V+ + ++ E L E++L + I+IS ++KYP+ L+E FE+ +D FF+ K W ++N Q Q + F E + K+ST CSFG Q +E+IE+ PI +G + N PMCDYM KFI +L L MN+VLENFT+LQ VTN+ T E+L+ + F EVS + S +Y+LI
Sbjct: 85 DLSGDAEGVWSIDIDQAFQEALAIYPPCGRRKIIISDEGKMYGRNELIARYIKLRCGKTRTRKQVSSHIQVLA-----------RKKLRDEQAKKKVPFHLNTGDIPSLLQ-----QASPPGGVKSPSAVVFPPVSAAVAAITEISPQSSYSSIVPKVETDQISQQLFKSLPLWSFQQTPGLPIGMDLSQLVFQQSSPDKTVSPVKSEV-------------------------VEETKPIASSQLTLHSFSAYVKCNKTSLRTE---------------LVKIENTLEK---DDIDISVFYEKYPKL--LRELFEKSEKKDVFFLAKCWANINVSDDVQNCQYAVDSFYSSREKFQLKVSTMACSFGNQAVEKIEQYFPIEFDGSYSFILNNSPMCDYMVKFIAELKKLNVIETMNNVLENFTVLQIVTNSETDELLMVLCFVFEVSQEPEPS-CSVYRLI 484
BLAST of SD2 vs. Ensembl Celegans
Match: egl-44 (Transcription enhancer factor-like protein egl-44 [Source:UniProtKB/Swiss-Prot;Acc:Q19849]) HSP 1 Score: 203.371 bits (516), Expect = 5.414e-59 Identity = 154/462 (33.33%), Postives = 230/462 (49.78%), Query Frame = 1
Query: 118 DESKEAEGVWSPDIENSFNEALQLYPPCGRRKIVLSEEGKMYGRNELIARYIKMQTGKSRSRKQVSSHIQVLARRKSKEIQNQIQEKHTREQARQQLA-NMSSAQIVSDFKIKENLSLCNDNRNKSPKFV-----DNNINSFSNTQGISRFSSIHHPTPLVANSKLLDTSSFLLRPNQIPPIMACTNTHNMYLKNDSPNDLISHNHTPIPAMWNVPHMXXXXXXXXXXXXXGPHLYVGRSIATPKMRLLELSVFVEAKEYPVKIEKGFGMKNYCKHVFAHLNSTESSLGHPFLEHIEISQIWDKYPETDGLKEYFERG-PQDAFFMVKFWIDMNFDVLPQWNQLSTIIF-EGVENVKSKLSTKICSFGRQVLERIEEQSPILENGISIYRFENVPMCDYMRKFIIKLSSLKEHSLMNSVLENFTILQTVTNAFTGEILLCIAFAMEVSISDQGSQYHIYKLI 1479
D S +AEGVWS DI+ +F EAL +YPPCGRRKI++S+EGKMYGRNELIARYIK++ GK+R+RKQVSSH IQ ++K EQA++++ ++++ I S + KSP V + + + S +SSI S+ L S L Q P + + + + SP+ +S + + + + IA+ ++ L S +V+ + ++ E L E++L + I+IS ++KYP+ L+E FE+ +D FF+ K W ++N Q Q + F E + K+ST CSFG Q +E+IE+ PI +G + N PMCDYM KFI +L L MN+VLENFT+LQ VTN+ T E+L+ + F EVS + S +Y+LI
Sbjct: 11 DLSGDAEGVWSIDIDQAFQEALAIYPPCGRRKIIISDEGKMYGRNELIARYIKLRCGKTRTRKQVSSH-----------IQVLARKKLRDEQAKKKVPFHLNTGDIPSLLQ-----QASPPGGVKSPSAVVFPPVSAAVAAITEISPQSSYSSIVPKVETDQISQQLFKSLPLWSFQQTPGLPIGMDLSQLVFQQSSPDKTVSPVKSEV-------------------------VEETKPIASSQLTLHSFSAYVKCNKTSLRTE---------------LVKIENTLEK---DDIDISVFYEKYPKL--LRELFEKSEKKDVFFLAKCWANINVSDDVQNCQYAVDSFYSSREKFQLKVSTMACSFGNQAVEKIEQYFPIEFDGSYSFILNNSPMCDYMVKFIAELKKLNVIETMNNVLENFTVLQIVTNSETDELLMVLCFVFEVSQEPEPS-CSVYRLI 410
BLAST of SD2 vs. Ensembl Fly
Match: sd (gene:FBgn0003345 transcript:FBtr0074100) HSP 1 Score: 185.652 bits (470), Expect = 9.676e-53 Identity = 100/229 (43.67%), Postives = 141/229 (61.57%), Query Frame = 1
Query: 811 GRSIATPKMRLLELSVFVEAKEYPVKIEKGFGMKNYCKHVFAHLNSTESSLGHPFLEHIEISQIWDKYPE-TDGLKEYFERGPQDAFFMVKFWIDMNFDVLPQWNQLS----TIIFEGVENVKSKLSTKICSFGRQVLERIEEQSPILENGISIYRFENVPMCDYMRKFIIKLSSLKEHSLMNSVLENFTILQTVTNAFTGEILLCIAFAMEVSISDQGSQYHIYKLIR 1482
GR+IAT K RLLE + F+E + + Y +H+F L + S P LE ++I QI+DK+PE + GLK+ +E+GPQ+AF++VK W D+N D+ T +E ENV ST +CSFG+QV+E++E + LEN +YR + PMC+YM FI KL +L E +MNSVLENFTILQ + T E LLCIA+ EV+ + G+ +HIY+LI+
Sbjct: 152 GRAIATHKFRLLEFTAFMEIQRDEI----------YHRHLFVQLGG-KPSFSDPLLETVDIRQIFDKFPEKSGGLKDLYEKGPQNAFYLVKCWADLNTDLTTGSETGDFYGVTSQYESNENVVLVCSTIVCSFGKQVVEKVESEYSRLENNRYVYRIQRSPMCEYMINFIQKLKNLPERYMMNSVLENFTILQVMRARETQETLLCIAYVFEVAAQNSGTTHHIYRLIK 369 HSP 2 Score: 148.673 bits (374), Expect = 3.039e-39 Identity = 69/100 (69.00%), Postives = 84/100 (84.00%), Query Frame = 1
Query: 73 SSNENICDSNNKNDFDESKEAEGVWSPDIENSFNEALQLYPPCGRRKIVLSEEGKMYGRNELIARYIKMQTGKSRSRKQVSSHIQVLARRKSKEIQNQIQ 372
S N ++ D ++ S +AEGVWSPDIE SF EAL +YPPCGRRKI+LS+EGKMYGRNELIARYIK++TGK+R+RKQVSSHIQVLARRK +EIQ +I+
Sbjct: 4 SKNLDVGDMSDDEKDLSSADAEGVWSPDIEQSFQEALSIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKLREIQAKIK 103
BLAST of SD2 vs. Ensembl Fly
Match: sd (gene:FBgn0003345 transcript:FBtr0308132) HSP 1 Score: 185.652 bits (470), Expect = 9.676e-53 Identity = 100/229 (43.67%), Postives = 141/229 (61.57%), Query Frame = 1
Query: 811 GRSIATPKMRLLELSVFVEAKEYPVKIEKGFGMKNYCKHVFAHLNSTESSLGHPFLEHIEISQIWDKYPE-TDGLKEYFERGPQDAFFMVKFWIDMNFDVLPQWNQLS----TIIFEGVENVKSKLSTKICSFGRQVLERIEEQSPILENGISIYRFENVPMCDYMRKFIIKLSSLKEHSLMNSVLENFTILQTVTNAFTGEILLCIAFAMEVSISDQGSQYHIYKLIR 1482
GR+IAT K RLLE + F+E + + Y +H+F L + S P LE ++I QI+DK+PE + GLK+ +E+GPQ+AF++VK W D+N D+ T +E ENV ST +CSFG+QV+E++E + LEN +YR + PMC+YM FI KL +L E +MNSVLENFTILQ + T E LLCIA+ EV+ + G+ +HIY+LI+
Sbjct: 152 GRAIATHKFRLLEFTAFMEIQRDEI----------YHRHLFVQLGG-KPSFSDPLLETVDIRQIFDKFPEKSGGLKDLYEKGPQNAFYLVKCWADLNTDLTTGSETGDFYGVTSQYESNENVVLVCSTIVCSFGKQVVEKVESEYSRLENNRYVYRIQRSPMCEYMINFIQKLKNLPERYMMNSVLENFTILQVMRARETQETLLCIAYVFEVAAQNSGTTHHIYRLIK 369 HSP 2 Score: 148.673 bits (374), Expect = 3.039e-39 Identity = 69/100 (69.00%), Postives = 84/100 (84.00%), Query Frame = 1
Query: 73 SSNENICDSNNKNDFDESKEAEGVWSPDIENSFNEALQLYPPCGRRKIVLSEEGKMYGRNELIARYIKMQTGKSRSRKQVSSHIQVLARRKSKEIQNQIQ 372
S N ++ D ++ S +AEGVWSPDIE SF EAL +YPPCGRRKI+LS+EGKMYGRNELIARYIK++TGK+R+RKQVSSHIQVLARRK +EIQ +I+
Sbjct: 4 SKNLDVGDMSDDEKDLSSADAEGVWSPDIEQSFQEALSIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKLREIQAKIK 103
BLAST of SD2 vs. Ensembl Fly
Match: sd (gene:FBgn0003345 transcript:FBtr0074101) HSP 1 Score: 185.652 bits (470), Expect = 9.676e-53 Identity = 100/229 (43.67%), Postives = 141/229 (61.57%), Query Frame = 1
Query: 811 GRSIATPKMRLLELSVFVEAKEYPVKIEKGFGMKNYCKHVFAHLNSTESSLGHPFLEHIEISQIWDKYPE-TDGLKEYFERGPQDAFFMVKFWIDMNFDVLPQWNQLS----TIIFEGVENVKSKLSTKICSFGRQVLERIEEQSPILENGISIYRFENVPMCDYMRKFIIKLSSLKEHSLMNSVLENFTILQTVTNAFTGEILLCIAFAMEVSISDQGSQYHIYKLIR 1482
GR+IAT K RLLE + F+E + + Y +H+F L + S P LE ++I QI+DK+PE + GLK+ +E+GPQ+AF++VK W D+N D+ T +E ENV ST +CSFG+QV+E++E + LEN +YR + PMC+YM FI KL +L E +MNSVLENFTILQ + T E LLCIA+ EV+ + G+ +HIY+LI+
Sbjct: 152 GRAIATHKFRLLEFTAFMEIQRDEI----------YHRHLFVQLGG-KPSFSDPLLETVDIRQIFDKFPEKSGGLKDLYEKGPQNAFYLVKCWADLNTDLTTGSETGDFYGVTSQYESNENVVLVCSTIVCSFGKQVVEKVESEYSRLENNRYVYRIQRSPMCEYMINFIQKLKNLPERYMMNSVLENFTILQVMRARETQETLLCIAYVFEVAAQNSGTTHHIYRLIK 369 HSP 2 Score: 148.673 bits (374), Expect = 3.039e-39 Identity = 69/100 (69.00%), Postives = 84/100 (84.00%), Query Frame = 1
Query: 73 SSNENICDSNNKNDFDESKEAEGVWSPDIENSFNEALQLYPPCGRRKIVLSEEGKMYGRNELIARYIKMQTGKSRSRKQVSSHIQVLARRKSKEIQNQIQ 372
S N ++ D ++ S +AEGVWSPDIE SF EAL +YPPCGRRKI+LS+EGKMYGRNELIARYIK++TGK+R+RKQVSSHIQVLARRK +EIQ +I+
Sbjct: 4 SKNLDVGDMSDDEKDLSSADAEGVWSPDIEQSFQEALSIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKLREIQAKIK 103
BLAST of SD2 vs. Ensembl Fly
Match: sd (gene:FBgn0003345 transcript:FBtr0308130) HSP 1 Score: 185.652 bits (470), Expect = 9.676e-53 Identity = 100/229 (43.67%), Postives = 141/229 (61.57%), Query Frame = 1
Query: 811 GRSIATPKMRLLELSVFVEAKEYPVKIEKGFGMKNYCKHVFAHLNSTESSLGHPFLEHIEISQIWDKYPE-TDGLKEYFERGPQDAFFMVKFWIDMNFDVLPQWNQLS----TIIFEGVENVKSKLSTKICSFGRQVLERIEEQSPILENGISIYRFENVPMCDYMRKFIIKLSSLKEHSLMNSVLENFTILQTVTNAFTGEILLCIAFAMEVSISDQGSQYHIYKLIR 1482
GR+IAT K RLLE + F+E + + Y +H+F L + S P LE ++I QI+DK+PE + GLK+ +E+GPQ+AF++VK W D+N D+ T +E ENV ST +CSFG+QV+E++E + LEN +YR + PMC+YM FI KL +L E +MNSVLENFTILQ + T E LLCIA+ EV+ + G+ +HIY+LI+
Sbjct: 152 GRAIATHKFRLLEFTAFMEIQRDEI----------YHRHLFVQLGG-KPSFSDPLLETVDIRQIFDKFPEKSGGLKDLYEKGPQNAFYLVKCWADLNTDLTTGSETGDFYGVTSQYESNENVVLVCSTIVCSFGKQVVEKVESEYSRLENNRYVYRIQRSPMCEYMINFIQKLKNLPERYMMNSVLENFTILQVMRARETQETLLCIAYVFEVAAQNSGTTHHIYRLIK 369 HSP 2 Score: 148.673 bits (374), Expect = 3.039e-39 Identity = 69/100 (69.00%), Postives = 84/100 (84.00%), Query Frame = 1
Query: 73 SSNENICDSNNKNDFDESKEAEGVWSPDIENSFNEALQLYPPCGRRKIVLSEEGKMYGRNELIARYIKMQTGKSRSRKQVSSHIQVLARRKSKEIQNQIQ 372
S N ++ D ++ S +AEGVWSPDIE SF EAL +YPPCGRRKI+LS+EGKMYGRNELIARYIK++TGK+R+RKQVSSHIQVLARRK +EIQ +I+
Sbjct: 4 SKNLDVGDMSDDEKDLSSADAEGVWSPDIEQSFQEALSIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKLREIQAKIK 103
BLAST of SD2 vs. Ensembl Fly
Match: sd (gene:FBgn0003345 transcript:FBtr0340115) HSP 1 Score: 185.267 bits (469), Expect = 1.418e-52 Identity = 100/229 (43.67%), Postives = 141/229 (61.57%), Query Frame = 1
Query: 811 GRSIATPKMRLLELSVFVEAKEYPVKIEKGFGMKNYCKHVFAHLNSTESSLGHPFLEHIEISQIWDKYPE-TDGLKEYFERGPQDAFFMVKFWIDMNFDVLPQWNQLS----TIIFEGVENVKSKLSTKICSFGRQVLERIEEQSPILENGISIYRFENVPMCDYMRKFIIKLSSLKEHSLMNSVLENFTILQTVTNAFTGEILLCIAFAMEVSISDQGSQYHIYKLIR 1482
GR+IAT K RLLE + F+E + + Y +H+F L + S P LE ++I QI+DK+PE + GLK+ +E+GPQ+AF++VK W D+N D+ T +E ENV ST +CSFG+QV+E++E + LEN +YR + PMC+YM FI KL +L E +MNSVLENFTILQ + T E LLCIA+ EV+ + G+ +HIY+LI+
Sbjct: 157 GRAIATHKFRLLEFTAFMEIQRDEI----------YHRHLFVQLGG-KPSFSDPLLETVDIRQIFDKFPEKSGGLKDLYEKGPQNAFYLVKCWADLNTDLTTGSETGDFYGVTSQYESNENVVLVCSTIVCSFGKQVVEKVESEYSRLENNRYVYRIQRSPMCEYMINFIQKLKNLPERYMMNSVLENFTILQVMRARETQETLLCIAYVFEVAAQNSGTTHHIYRLIK 374 HSP 2 Score: 149.443 bits (376), Expect = 1.510e-39 Identity = 76/127 (59.84%), Postives = 94/127 (74.02%), Query Frame = 1
Query: 73 SSNENICDSNNKNDFDESKEAEGVWSPDIENSFNEALQLYPPCGRRKIVLSEEGKMYGRNELIARYIKMQTGKSRSRKQVSSHIQVLARRKSKEIQNQIQEKHTREQARQQLANMSSAQIVSDFKIK 453
S N ++ D ++ S +AEGVWSPDIE SF EAL +YPPCGRRKI+LS+EGKMYGRNELIARYIK++TGK+R+RKQVSSHIQVLARRK +EIQ +I + Q Q S++Q D+ IK
Sbjct: 4 SKNLDVGDMSDDEKDLSSADAEGVWSPDIEQSFQEALSIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKLREIQAKI-----KVQFWQPGLQPSTSQDFYDYSIK 125
BLAST of SD2 vs. Ensembl Zebrafish
Match: tead3a (TEA domain family member 3 a [Source:ZFIN;Acc:ZDB-GENE-031112-10]) HSP 1 Score: 349.747 bits (896), Expect = 6.096e-115 Identity = 200/459 (43.57%), Postives = 272/459 (59.26%), Query Frame = 1
Query: 130 EAEGVWSPDIENSFNEALQLYPPCGRRKIVLSEEGKMYGRNELIARYIKMQTGKSRSRKQVSSHIQVLARRKSKEIQNQIQEKHTREQARQQLANMSSAQIVSDFKIKENLSLCNDNRNKSPK--FVDNNINSFSNTQGISRFSSIHHPTPLVANSKLLDTSSFLLRPNQIPPIMACTNTHNMYLKNDSPNDLISHNHTPIPAMWNVPHMXXXXXXXXXXXXXGPHLYVGRSIATPKMRLLELSVFVEAKEYPVKIEKGFGMKNYCKHVFAHLNSTESSLGHPFLEHIEISQIWDKYPET-DGLKEYFERGPQDAFFMVKFWIDMNF----DVLPQWNQLSTIIFEGVENVKSKLSTKICSFGRQVLERIEEQSPILENGISIYRFENVPMCDYMRKFIIKLSSLKEHSLMNSVLENFTILQTVTNAFTGEILLCIAFAMEVSISDQGSQYHIYKLIRN 1485
+AEGVWSPDIE SF EAL +YPPCGRRKI+LS+EGKMYGRNELIARYIK++TGK+R+RKQVSSHIQVLAR+K +E Q I+++ ++++A Q +A +SSAQIVS +K L + P + +Q I F+ +PT L+P PPI + Y + +P + + T +P +W R+IA+ K+R+LE S F+E + P Y KH+F H+ T S P LE ++I QI+DK+PE GLKE +E+GPQ+AFF+VKFW D+N D + +S+ + EN+ +STK+CSFG+QV+E++E + +E G +YR PMC+YM FI KL L E +MNSVLENFTILQ VTN T E LLCIAF EVS SD G+QYH+Y+L+++
Sbjct: 9 DAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARKKMREYQAGIKDQASKDKALQNMAALSSAQIVSASVMKSQLPPLPQHPYPPPARFWPGPIPGQPGPSQDIKPFAPSPYPT---------------LQP---PPISS-------YEQLPAP---LPPSATAVP-VWQ-----------------------DRTIASSKLRMLEYSAFMEVQRDP---------DTYSKHLFVHIAQTNPSYTDPLLEAVDIRQIYDKFPEKKGGLKELYEKGPQNAFFLVKFWADLNSSNVQDGAGSFYGVSSQ-YSSAENMTITVSTKVCSFGKQVVEKVETEYARVEGGRYVYRIHRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTNRDTQETLLCIAFVFEVSTSDHGAQYHVYRLVKD 405
BLAST of SD2 vs. Ensembl Zebrafish
Match: tead3a (TEA domain family member 3 a [Source:ZFIN;Acc:ZDB-GENE-031112-10]) HSP 1 Score: 343.584 bits (880), Expect = 1.390e-112 Identity = 200/463 (43.20%), Postives = 272/463 (58.75%), Query Frame = 1
Query: 130 EAEGVWSPDIENSFNEALQLYPPCGRRKIVLSEEGKMYGRNELIARYIKMQTGKSRSRKQVSSHIQVLARRKSKEIQNQIQ----EKHTREQARQQLANMSSAQIVSDFKIKENLSLCNDNRNKSPK--FVDNNINSFSNTQGISRFSSIHHPTPLVANSKLLDTSSFLLRPNQIPPIMACTNTHNMYLKNDSPNDLISHNHTPIPAMWNVPHMXXXXXXXXXXXXXGPHLYVGRSIATPKMRLLELSVFVEAKEYPVKIEKGFGMKNYCKHVFAHLNSTESSLGHPFLEHIEISQIWDKYPET-DGLKEYFERGPQDAFFMVKFWIDMNF----DVLPQWNQLSTIIFEGVENVKSKLSTKICSFGRQVLERIEEQSPILENGISIYRFENVPMCDYMRKFIIKLSSLKEHSLMNSVLENFTILQTVTNAFTGEILLCIAFAMEVSISDQGSQYHIYKLIRN 1485
+AEGVWSPDIE SF EAL +YPPCGRRKI+LS+EGKMYGRNELIARYIK++TGK+R+RKQVSSHIQVLAR+K +E Q I+ ++ ++++A Q +A +SSAQIVS +K L + P + +Q I F+ +PT L+P PPI + Y + +P + + T +P +W R+IA+ K+R+LE S F+E + P Y KH+F H+ T S P LE ++I QI+DK+PE GLKE +E+GPQ+AFF+VKFW D+N D + +S+ + EN+ +STK+CSFG+QV+E++E + +E G +YR PMC+YM FI KL L E +MNSVLENFTILQ VTN T E LLCIAF EVS SD G+QYH+Y+L+++
Sbjct: 9 DAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARKKMREYQAGIKAMNLDQASKDKALQNMAALSSAQIVSASVMKSQLPPLPQHPYPPPARFWPGPIPGQPGPSQDIKPFAPSPYPT---------------LQP---PPISS-------YEQLPAP---LPPSATAVP-VWQ-----------------------DRTIASSKLRMLEYSAFMEVQRDP---------DTYSKHLFVHIAQTNPSYTDPLLEAVDIRQIYDKFPEKKGGLKELYEKGPQNAFFLVKFWADLNSSNVQDGAGSFYGVSSQ-YSSAENMTITVSTKVCSFGKQVVEKVETEYARVEGGRYVYRIHRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTNRDTQETLLCIAFVFEVSTSDHGAQYHVYRLVKD 409
BLAST of SD2 vs. Ensembl Zebrafish
Match: tead1a (TEA domain family member 1a [Source:ZFIN;Acc:ZDB-GENE-040426-2101]) HSP 1 Score: 338.576 bits (867), Expect = 2.347e-110 Identity = 194/481 (40.33%), Postives = 267/481 (55.51%), Query Frame = 1
Query: 61 STTCSSNENICDSNNKNDFDESKEAEGVWSPDIENSFNEALQLYPPCGRRKIVLSEEGKMYGRNELIARYIKMQTGKSRSRKQVSSHIQVLARRKSKEIQNQIQEKHTREQARQQLANMSSAQIVSDFKIKENLSLCNDNRNKSPKFVD---NNINSFSNTQGISRFSSIHHPTPLVANSKLLDTSSFLLRPNQIPPIMACTNTHNMYLKNDSPNDLISHNHTPIPAMWNVPHMXXXXXXXXXXXXXGPHLYVGRSIATPKMRLLELSVFVEAKEYPVKIEKGFGMKNYCKHVFAHLNSTESSLGHPFLEHIEISQIWDKYPET-DGLKEYFERGPQDAFFMVKFWIDMNFDVLPQWNQLSTII--FEGVENVKSKLSTKICSFGRQVLERIEEQSPILENGISIYRFENVPMCDYMRKFIIKLSSLKEHSLMNSVLENFTILQTVTNAFTGEILLCIAFAMEVSISDQGSQYHIYKLIRN 1485
S + S+ E+I ++ D +AEGVWSPDIE SF EAL +YPPCGRRKI+LS+EGKMYGRNELIARYIK++TGK+R+RKQVSSHIQVLARRKS+E +++++ + A ++ +SSAQIVS I L L R+ P + ++Q + FS ++P ++S+ L +PP W+ GRSI T K+RL+E S F+E + P Y KH+F H+ T S LE ++I QI+DK+PE GLKE F +GPQ+AFF+VKFW D+N ++ + +E EN+ STK+CSFG+QV+E++E + ENG +Y+ PMC+YM FI KL L E +MNSVLENFTIL V+N T E LLC+A EVS S+ G+Q+HIY+L+++
Sbjct: 7 SGSESAGEDIERMSDSADKPMDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSREFHSKLKDHTVKNDAINRMGGISSAQIVSATAIHSRLGLAGLPRSALPGATGIWQVSTGQPGSSQDVKPFSQQNYPIQTTTAIAAYESSTAL--SAAVPP-------------------------------WH-----------------------GRSIGTSKLRLVEFSAFLEHQRDP---------DLYNKHLFVHIGQTNYSYSDALLETVDIRQIYDKFPEKKGGLKELFGKGPQNAFFLVKFWADLNCNIQEDSGSFYGVTSQYESSENMTITCSTKVCSFGKQVVEKVETEYARFENGRFVYKISRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILLVVSNRETQETLLCMACVFEVSNSEHGAQHHIYRLVKD 422
BLAST of SD2 vs. Ensembl Zebrafish
Match: tead1b (TEA domain family member 1b [Source:ZFIN;Acc:ZDB-GENE-091013-5]) HSP 1 Score: 259.61 bits (662), Expect = 1.491e-80 Identity = 167/437 (38.22%), Postives = 230/437 (52.63%), Query Frame = 1
Query: 244 GRNELIARYIKMQTGKSRSRKQVSSHIQVLAR---------------------RKSKEIQNQIQEKHTREQARQQLANMSSAQIVSDFKIKENLSLCNDNRNKSPKFVDNNINSFSNTQGISRFSSIHHPTPLVANSKLLDTSSFLLRPNQIPPIMACTNTHNMYLKNDSPNDLISHNHTPIPAMWNVPHMXXXXXXXXXXXXXGPHLYVGRSIATPKMRLLELSVFVEAKEYPVKIEKGFGMKNYCKHVFAHLNSTESSLGHPFLEHIEISQIWDKYPET-DGLKEYFERGPQDAFFMVKFWIDMNFDVLPQWNQLSTII--FEGVENVKSKLSTKICSFGRQVLERIEEQSPILENGISIYRFENVPMCDYMRKFIIKLSSLKEHSLMNSVLENFTILQTVTNAFTGEILLCIAFAMEVSISDQGSQYHIYKLIR 1482
GRNELIARYIK++TGK+R+RKQVSSHIQVLAR RKS+E+ ++++++ +++A Q +A+MSSAQIVS I L L R P G + F PT +S+ D F + I P A T T + Y +P + W GRSI T K+RL+E S F+E + P +Y KH+F H+ T S LE ++I QI+DK+PE GLKE F +GPQ++FF++KFW D+N ++ + + +E EN+ STK+CSFG+QV+E++E + ENG +YR PMC+YM FI KL L E +MNSVLENFTIL VTN T E LLC+A EVS S+ G+Q+HIY+L++
Sbjct: 1 GRNELIARYIKLRTGKTRTRKQVSSHIQVLARKKVREIQAAIKVSSHIQVLARRKSRELHSKLKDQSVKDKALQTMASMSSAQIVSATAIHNKLGLPGIPRPAFP--------------GAAGFWQGMIPTGQPGSSQ--DIKPFAQQAYPIQP--AVTTTISSYEPPTAPAPTVP--------AWQ-----------------------GRSIGTSKLRLVEFSAFLEHQRDP---------DSYNKHLFVHIGQTNHSYNDALLESVDIRQIYDKFPEKKGGLKELFGKGPQNSFFLIKFWADLNCNIQDETGAFYGVTSQYESPENMTITCSTKVCSFGKQVVEKVETEYARFENGRFVYRISRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILLVVTNRDTQETLLCMACVFEVSNSEHGAQHHIYRLVK 379
BLAST of SD2 vs. Ensembl Zebrafish
Match: tead3b (TEA domain family member 3 b [Source:ZFIN;Acc:ZDB-GENE-080103-3]) HSP 1 Score: 230.335 bits (586), Expect = 4.087e-69 Identity = 162/460 (35.22%), Postives = 233/460 (50.65%), Query Frame = 1
Query: 130 EAEGVWSPDIENSFNEALQLYPPCGRRKIVLSEEGKMYGRNELIARYIKMQTGKSRSRKQVSSHIQVLARRKSKEIQNQIQEKHTREQARQQLANMSSAQIVSDFKIKENLSLCNDNRNKSPKFVDNNINSFSNTQGISRFSSIHHPTPLVANSKLLDTSSFLLRPNQIPPIMACTNTHNMYLKNDSPNDLISHNHTPIPAMWNVPHMXXXXXXXXXXXXXGPHLYVGRSIATPKMRLLELSVFVEAKEYPVKIEKGFGMKNYCKHVFAHLNSTESSLGHPFLEHIEISQIWDKYPET-DGLKEYFERGPQDAFFMVKFWIDMNFDVLPQWNQLSTIIFEGV-------ENVKSKLSTKICSFGRQVLERIEEQSPILENGISIYRFENVPMCDYMRKFIIKLSSLKEHSLMNSVLENFTILQTVTNAFTGEILLCIAFAMEVSISDQGSQYHIYKLIRN 1485
+AEGVWSPDIE SF EAL +YPPC GR ++I GK R ++ I I+ + + + R+Q++ S Q+++ K +E S D +K N+ + S+ Q +S S I T L + + P IP + ++ N PN L + I A ++ + + + R+IA+ K+R+LE S F+E + +Y KH+F H+ T S P LE ++I QI+DK+PE GLKE +E+GPQ+AFF+VKFW D+N + Q F GV EN+ +STK+CSFG+QV+E++E + ++ G +YR PMC+YM FI KL L E +MNSVLENFTILQ VTN T E LLCIAF EVS S+ G+QYH+Y+LI++
Sbjct: 4 DAEGVWSPDIEQSFQEALAIYPPC--------------GRRKIILS----DEGKMYGRNEL--------------IARYIKLRTGKTRTRKQVS--SHLQVLARRKSREIQSKLKDQASKDKAL--QNMAALSSAQIVSP-SLIK--TSLPPLPQSPYPPAARFWPTPIPGQPGPSQDIKPFV-NPYPN-LSGPVQSTISAYESLAPPPPPVATAVPV-------WQDRTIASSKLRMLEYSAFMELPQ---------DQDSYSKHLFVHIGQTNPSYSDPLLEAVDIRQIYDKFPEKKGGLKELYEKGPQNAFFLVKFWADLNNSSV----QDGPGSFYGVSSQYSSSENMTITVSTKVCSFGKQVVEKVETEYAHVDGGKCLYRIHRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTNRETQETLLCIAFVFEVSTSEHGAQYHVYRLIKD 402
BLAST of SD2 vs. Ensembl Xenopus
Match: pik3ca (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha [Source:Xenbase;Acc:XB-GENE-998106]) HSP 1 Score: 355.91 bits (912), Expect = 6.928e-117 Identity = 201/484 (41.53%), Postives = 283/484 (58.47%), Query Frame = 1
Query: 55 ECSTTCSSNENICDSNNKNDFDESKEAEGVWSPDIENSFNEALQLYPPCGRRKIVLSEEGKMYGRNELIARYIKMQTGKSRSRKQVSSHIQVLARRKSKEIQNQIQEKHTREQARQQLANMSSAQIVSDFKIKENLSLCNDNRNKSPKFVDNNINSFSNTQGISRF----SSIHHPTPLVANSKLLDTSSFLLRPNQIPPIMACTNTHNMYLKNDSPNDLISHNHTPIPAMWNVPHMXXXXXXXXXXXXXGPHLYVGRSIATPKMRLLELSVFVEAKEYPVKIEKGFGMKNYCKHVFAHLNSTESSLGHPFLEHIEISQIWDKYPET-DGLKEYFERGPQDAFFMVKFWIDMNFDVLPQWNQLSTII--FEGVENVKSKLSTKICSFGRQVLERIEEQSPILENGISIYRFENVPMCDYMRKFIIKLSSLKEHSLMNSVLENFTILQTVTNAFTGEILLCIAFAMEVSISDQGSQYHIYKLIRN 1485
E + S ++ DS K+ +AEGVWSPDIE SF EAL +YPPCGRRKI+LS+EGKMYGRNELIARYIK++TGK+R+RKQVSSHIQVLARRKS+EIQ++++++ +++A Q +A MSSAQ++S I+ L + + ++ F T G F P P + K + L+ PP + N SP L +P+P+ GP + GRSI TPK+RL+E F+E + P Y KH++ H++ + S LE +++ QI+DK+PE GLKE +E+GP +AFF+VKFW D+N + + + +E EN+ S+K+CSFG+QV+E++E + ENG +YR PMC+Y+ FI KL L E +MNSVLENFTILQ VTN T E+LLCIA+ EVS S+ G+Q+HIY+L+++
Sbjct: 8 EAGSPAESTGDLGDSMEKS---LDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSREIQSKLKDQVAKDKALQSMAAMSSAQLISATAIQNKLGVSSISQA-----------PFPPTPGTPDFFQFWPGGGQPRP-TQDVKPFSQPPYPLQSAAPPPAVPGYNA--------SPASL-----SPVPS--------------------GP-AWQGRSIGTPKLRLVEFLAFMEQQGEP---------DAYNKHLYVHISQSNPSYSDALLESVDVRQIYDKFPEKKGGLKELYEKGPPNAFFLVKFWADLNTSIQDEPGVFYGVSSQYESPENMTITCSSKVCSFGKQVVEKVETEYARFENGRFLYRIHRSPMCEYLINFIHKLKQLPEKYMMNSVLENFTILQVVTNRDTQELLLCIAYVFEVSTSEHGAQHHIYRLVKD 433
BLAST of SD2 vs. Ensembl Xenopus
Match: pik3ca (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha [Source:Xenbase;Acc:XB-GENE-998106]) HSP 1 Score: 351.288 bits (900), Expect = 2.258e-115 Identity = 200/480 (41.67%), Postives = 278/480 (57.92%), Query Frame = 1
Query: 55 ECSTTCSSNENICDSNNKNDFDESKEAEGVWSPDIENSFNEALQLYPPCGRRKIVLSEEGKMYGRNELIARYIKMQTGKSRSRKQVSSHIQVLARRKSKEIQNQIQEKHTREQARQQLANMSSAQIVSDFKIKENLSLCNDNRNKSPKFVDNNINSFSNTQGISRFSSIHHPTPLVANSKLLDTSSFLLRPNQIPPIMACTNTHNMYLKNDSPNDLISHNHTPIPAMWNVPHMXXXXXXXXXXXXXGPHLYVGRSIATPKMRLLELSVFVEAKEYPVKIEKGFGMKNYCKHVFAHLNSTESSLGHPFLEHIEISQIWDKYPET-DGLKEYFERGPQDAFFMVKFWIDMNFDVLPQWNQLSTII--FEGVENVKSKLSTKICSFGRQVLERIEEQSPILENGISIYRFENVPMCDYMRKFIIKLSSLKEHSLMNSVLENFTILQTVTNAFTGEILLCIAFAMEVSISDQGSQYHIYKLIRN 1485
E + S ++ DS K+ D +AEGVWSPDIE SF EAL +YPPCGRRKI+LS+EGKMYGRNELIARYIK++TGK+R+RKQVSSHIQVLARRKS+EIQ++++++ +++A Q +A MSSAQ++S I+ L G+S S A K + L+ PP + N SP L +P+P+ GP + GRSI TPK+RL+E F+E + P Y KH++ H++ + S LE +++ QI+DK+PE GLKE +E+GP +AFF+VKFW D+N + + + +E EN+ S+K+CSFG+QV+E++E + ENG +YR PMC+Y+ FI KL L E +MNSVLENFTILQ VTN T E+LLCIA+ EVS S+ G+Q+HIY+L+++
Sbjct: 6 EAGSPAESTGDLGDSMEKS-LD--NDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSREIQSKLKDQVAKDKALQSMAAMSSAQLISATAIQNKL-------------------------GVSSISQ--------APVKPFSQPPYPLQSAAPPPAVPGYNA--------SPASL-----SPVPS--------------------GP-AWQGRSIGTPKLRLVEFLAFMEQQGEP---------DAYNKHLYVHISQSNPSYSDALLESVDVRQIYDKFPEKKGGLKELYEKGPPNAFFLVKFWADLNTSIQDEPGVFYGVSSQYESPENMTITCSSKVCSFGKQVVEKVETEYARFENGRFLYRIHRSPMCEYLINFIHKLKQLPEKYMMNSVLENFTILQVVTNRDTQELLLCIAYVFEVSTSEHGAQHHIYRLVKD 406
BLAST of SD2 vs. Ensembl Xenopus
Match: pik3ca (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha [Source:Xenbase;Acc:XB-GENE-998106]) HSP 1 Score: 350.903 bits (899), Expect = 6.133e-115 Identity = 200/480 (41.67%), Postives = 285/480 (59.38%), Query Frame = 1
Query: 55 ECSTTCSSNENICDSNNKNDFDESKEAEGVWSPDIENSFNEALQLYPPCGRRKIVLSEEGKMYGRNELIARYIKMQTGKSRSRKQVSSHIQVLARRKSKEIQNQIQEKHTREQARQQLANMSSAQIVSDFKIKENLSLCNDNRNKSPKFVDNNINSFSNTQGISRFSSIHHPTPLVANSKLLDTSSFLLRPNQIPPIMACTNTHNMYLKNDSPNDLISHNHTPIPAMWNVPHMXXXXXXXXXXXXXGPHLYVGRSIATPKMRLLELSVFVEAKEYPVKIEKGFGMKNYCKHVFAHLNSTESSLGHPFLEHIEISQIWDKYPET-DGLKEYFERGPQDAFFMVKFWIDMNFDVLPQWNQLSTII--FEGVENVKSKLSTKICSFGRQVLERIEEQSPILENGISIYRFENVPMCDYMRKFIIKLSSLKEHSLMNSVLENFTILQTVTNAFTGEILLCIAFAMEVSISDQGSQYHIYKLIRN 1485
E + S ++ DS K+ +AEGVWSPDIE SF EAL +YPPCGRRKI+LS+EGKMYGRNELIARYIK++TGK+R+RKQVSSHIQVLARRKS+EIQ++++++ +++A Q +A MSSAQ++S I+ L + + S I+ F +S F + + + + K + L+ PP + N SP L +P+P+ GP + GRSI TPK+RL+E F+E + P Y KH++ H++ + S LE +++ QI+DK+PE GLKE +E+GP +AFF+VKFW D+N + + + +E EN+ S+K+CSFG+QV+E++E + ENG +YR PMC+Y+ FI KL L E +MNSVLENFTILQ VTN T E+LLCIA+ EVS S+ G+Q+HIY+L+++
Sbjct: 8 EAGSPAESTGDLGDSMEKS---LDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSREIQSKLKDQVAKDKALQSMAAMSSAQLISATAIQNKLGVSRLKGDVS------TIHLF-----MSLF--LFYFCIISLSVKPFSQPPYPLQSAAPPPAVPGYNA--------SPASL-----SPVPS--------------------GP-AWQGRSIGTPKLRLVEFLAFMEQQGEP---------DAYNKHLYVHISQSNPSYSDALLESVDVRQIYDKFPEKKGGLKELYEKGPPNAFFLVKFWADLNTSIQDEPGVFYGVSSQYESPENMTITCSSKVCSFGKQVVEKVETEYARFENGRFLYRIHRSPMCEYLINFIHKLKQLPEKYMMNSVLENFTILQVVTNRDTQELLLCIAYVFEVSTSEHGAQHHIYRLVKD 428
BLAST of SD2 vs. Ensembl Xenopus
Match: pik3ca (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha [Source:Xenbase;Acc:XB-GENE-998106]) HSP 1 Score: 350.903 bits (899), Expect = 8.716e-115 Identity = 201/488 (41.19%), Postives = 283/488 (57.99%), Query Frame = 1
Query: 55 ECSTTCSSNENICDSNNKNDFDESKEAEGVWSPDIENSFNEALQLYPPCGRRKIVLSEEGKMYGRNELIARYIKMQTGKSRSRKQVSSHIQVLARRKSKEIQNQIQ----EKHTREQARQQLANMSSAQIVSDFKIKENLSLCNDNRNKSPKFVDNNINSFSNTQGISRF----SSIHHPTPLVANSKLLDTSSFLLRPNQIPPIMACTNTHNMYLKNDSPNDLISHNHTPIPAMWNVPHMXXXXXXXXXXXXXGPHLYVGRSIATPKMRLLELSVFVEAKEYPVKIEKGFGMKNYCKHVFAHLNSTESSLGHPFLEHIEISQIWDKYPET-DGLKEYFERGPQDAFFMVKFWIDMNFDVLPQWNQLSTII--FEGVENVKSKLSTKICSFGRQVLERIEEQSPILENGISIYRFENVPMCDYMRKFIIKLSSLKEHSLMNSVLENFTILQTVTNAFTGEILLCIAFAMEVSISDQGSQYHIYKLIRN 1485
E + S ++ DS K+ +AEGVWSPDIE SF EAL +YPPCGRRKI+LS+EGKMYGRNELIARYIK++TGK+R+RKQVSSHIQVLARRKS+EIQ++++ ++ +++A Q +A MSSAQ++S I+ L + + ++ F T G F P P + K + L+ PP + N SP L +P+P+ GP + GRSI TPK+RL+E F+E + P Y KH++ H++ + S LE +++ QI+DK+PE GLKE +E+GP +AFF+VKFW D+N + + + +E EN+ S+K+CSFG+QV+E++E + ENG +YR PMC+Y+ FI KL L E +MNSVLENFTILQ VTN T E+LLCIA+ EVS S+ G+Q+HIY+L+++
Sbjct: 8 EAGSPAESTGDLGDSMEKS---LDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSREIQSKLKAMNMDQVAKDKALQSMAAMSSAQLISATAIQNKLGVSSISQA-----------PFPPTPGTPDFFQFWPGGGQPRP-TQDVKPFSQPPYPLQSAAPPPAVPGYNA--------SPASL-----SPVPS--------------------GP-AWQGRSIGTPKLRLVEFLAFMEQQGEP---------DAYNKHLYVHISQSNPSYSDALLESVDVRQIYDKFPEKKGGLKELYEKGPPNAFFLVKFWADLNTSIQDEPGVFYGVSSQYESPENMTITCSSKVCSFGKQVVEKVETEYARFENGRFLYRIHRSPMCEYLINFIHKLKQLPEKYMMNSVLENFTILQVVTNRDTQELLLCIAYVFEVSTSEHGAQHHIYRLVKD 437
BLAST of SD2 vs. Ensembl Xenopus
Match: pik3ca (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha [Source:Xenbase;Acc:XB-GENE-998106]) HSP 1 Score: 344.354 bits (882), Expect = 3.322e-113 Identity = 193/456 (42.32%), Postives = 266/456 (58.33%), Query Frame = 1
Query: 130 EAEGVWSPDIENSFNEALQLYPPCGRRKIVLSEEGKMYGRNELIARYIKMQTGKSRSRKQVSSHIQVLARRKSKEIQNQIQEKHTREQARQQLANMSSAQIVSDFKIKENLSLCNDNRNKSPKFVDNNINSFSNTQGISRFS-SIHHPTPLVANSKLLDTSSFLLRPNQIPPIMACTNTHNMYLKNDSPNDLISHNHTPIPAMWNVPHMXXXXXXXXXXXXXGPHLYVGRSIATPKMRLLELSVFVEAKEYPVKIEKGFGMKNYCKHVFAHLNSTESSLGHPFLEHIEISQIWDKYPET-DGLKEYFERGPQDAFFMVKFWIDMNFDVLPQWNQLSTII--FEGVENVKSKLSTKICSFGRQVLERIEEQSPILENGISIYRFENVPMCDYMRKFIIKLSSLKEHSLMNSVLENFTILQTVTNAFTGEILLCIAFAMEVSISDQGSQYHIYKLIRN 1485
+AEGVWSPDIE SF EAL +YPPCGRRKI+LS+EGKMYGRNELIARYIK++TGK+R+RKQVSSHIQVLARRKS+EIQ++++++ +++A Q +A MSSAQ++S I+ N G+S S + PTP V+ N SP L +P+P+ GP + GRSI TPK+RL+E F+E + P Y KH++ H++ + S LE +++ QI+DK+PE GLKE +E+GP +AFF+VKFW D+N + + + +E EN+ S+K+CSFG+QV+E++E + ENG +YR PMC+Y+ FI KL L E +MNSVLENFTILQ VTN T E+LLCIA+ EVS S+ G+Q+HIY+L+++
Sbjct: 8 DAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSREIQSKLKDQVAKDKALQSMAAMSSAQLISATAIQ-------------------------NKLGVSSISQAPFPPTPGVSY-------------------------------NASPASL-----SPVPS--------------------GP-AWQGRSIGTPKLRLVEFLAFMEQQGEP---------DAYNKHLYVHISQSNPSYSDALLESVDVRQIYDKFPEKKGGLKELYEKGPPNAFFLVKFWADLNTSIQDEPGVFYGVSSQYESPENMTITCSSKVCSFGKQVVEKVETEYARFENGRFLYRIHRSPMCEYLINFIHKLKQLPEKYMMNSVLENFTILQVVTNRDTQELLLCIAYVFEVSTSEHGAQHHIYRLVKD 372
BLAST of SD2 vs. Ensembl Mouse
Match: Tead1 (TEA domain family member 1 [Source:MGI Symbol;Acc:MGI:101876]) HSP 1 Score: 344.354 bits (882), Expect = 1.040e-112 Identity = 201/476 (42.23%), Postives = 269/476 (56.51%), Query Frame = 1
Query: 82 ENICDSNNKNDFDESKEAEGVWSPDIENSFNEALQLYPPCGRRKIVLSEEGKMYGRNELIARYIKMQTGKSRSRKQVSSHIQVLARRKSKEIQNQIQEKHTREQARQQLANMSSAQIVSDFKIKENLSLCNDNRNK---SPKFVDNNINSF--SNTQGISRFSSIHHPTPLVANSKLLDTSSFLLRPNQIPPIMACTNTHNMYLKNDSPNDLISHNHTPIPAMWNVPHMXXXXXXXXXXXXXGPHLYVGRSIATPKMRLLELSVFVEAKEYPVKIEKGFGMKNYCKHVFAHLNSTESSLGHPFLEHIEISQIWDKYPET-DGLKEYFERGPQDAFFMVKFWIDMNFDVLPQWNQLSTII--FEGVENVKSKLSTKICSFGRQVLERIEEQSPILENGISIYRFENVPMCDYMRKFIIKLSSLKEHSLMNSVLENFTILQTVTNAFTGEILLCIAFAMEVSISDQGSQYHIYKLIRN 1485
E + DS +K +AEGVWSPDIE SF EAL +YPPCGRRKI+LS+EGKMYGRNELIARYIK++TGK+R+RKQVSSHIQVLARRKS++ ++++++ +++A Q +A MSSAQIVS I L L R P F I + ++Q + F +P ++P PI T P P+ VP + GRSI T K+RL+E S F+E + P +Y KH+F H+ S P LE ++I QI+DK+PE GLKE F +GPQ+AFF+VKFW D+N ++ + +E EN+ STK+CSFG+QV+E++E + ENG +YR PMC+YM FI KL L E +MNSVLENFTIL VTN T E LLC+A EVS S+ G+Q+HIY+L+++
Sbjct: 2 ERMSDSADK---PIDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSRDFHSKLKDQTAKDKALQHMAAMSSAQIVSATAIHNKLGLPGIPRPTFPGGPGFWPGMIQTGQPGSSQDVKPFVQQAYP----------------IQPAVTAPIPGFEPTS-----------------APAPS---VP------------------AWQGRSIGTTKLRLVEFSAFLEQQRDP---------DSYNKHLFVHIGHANHSYSDPLLESVDIRQIYDKFPEKKGGLKELFGKGPQNAFFLVKFWADLNCNIQDDAGAFYGVSSQYESSENMTVTCSTKVCSFGKQVVEKVETEYARFENGRFVYRINRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILLVVTNRDTQETLLCMACVFEVSNSEHGAQHHIYRLVKD 411
BLAST of SD2 vs. Ensembl Mouse
Match: Tead1 (TEA domain family member 1 [Source:MGI Symbol;Acc:MGI:101876]) HSP 1 Score: 344.354 bits (882), Expect = 1.040e-112 Identity = 201/476 (42.23%), Postives = 269/476 (56.51%), Query Frame = 1
Query: 82 ENICDSNNKNDFDESKEAEGVWSPDIENSFNEALQLYPPCGRRKIVLSEEGKMYGRNELIARYIKMQTGKSRSRKQVSSHIQVLARRKSKEIQNQIQEKHTREQARQQLANMSSAQIVSDFKIKENLSLCNDNRNK---SPKFVDNNINSF--SNTQGISRFSSIHHPTPLVANSKLLDTSSFLLRPNQIPPIMACTNTHNMYLKNDSPNDLISHNHTPIPAMWNVPHMXXXXXXXXXXXXXGPHLYVGRSIATPKMRLLELSVFVEAKEYPVKIEKGFGMKNYCKHVFAHLNSTESSLGHPFLEHIEISQIWDKYPET-DGLKEYFERGPQDAFFMVKFWIDMNFDVLPQWNQLSTII--FEGVENVKSKLSTKICSFGRQVLERIEEQSPILENGISIYRFENVPMCDYMRKFIIKLSSLKEHSLMNSVLENFTILQTVTNAFTGEILLCIAFAMEVSISDQGSQYHIYKLIRN 1485
E + DS +K +AEGVWSPDIE SF EAL +YPPCGRRKI+LS+EGKMYGRNELIARYIK++TGK+R+RKQVSSHIQVLARRKS++ ++++++ +++A Q +A MSSAQIVS I L L R P F I + ++Q + F +P ++P PI T P P+ VP + GRSI T K+RL+E S F+E + P +Y KH+F H+ S P LE ++I QI+DK+PE GLKE F +GPQ+AFF+VKFW D+N ++ + +E EN+ STK+CSFG+QV+E++E + ENG +YR PMC+YM FI KL L E +MNSVLENFTIL VTN T E LLC+A EVS S+ G+Q+HIY+L+++
Sbjct: 2 ERMSDSADK---PIDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSRDFHSKLKDQTAKDKALQHMAAMSSAQIVSATAIHNKLGLPGIPRPTFPGGPGFWPGMIQTGQPGSSQDVKPFVQQAYP----------------IQPAVTAPIPGFEPTS-----------------APAPS---VP------------------AWQGRSIGTTKLRLVEFSAFLEQQRDP---------DSYNKHLFVHIGHANHSYSDPLLESVDIRQIYDKFPEKKGGLKELFGKGPQNAFFLVKFWADLNCNIQDDAGAFYGVSSQYESSENMTVTCSTKVCSFGKQVVEKVETEYARFENGRFVYRINRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILLVVTNRDTQETLLCMACVFEVSNSEHGAQHHIYRLVKD 411
BLAST of SD2 vs. Ensembl Mouse
Match: Tead1 (TEA domain family member 1 [Source:MGI Symbol;Acc:MGI:101876]) HSP 1 Score: 339.347 bits (869), Expect = 8.951e-111 Identity = 203/480 (42.29%), Postives = 268/480 (55.83%), Query Frame = 1
Query: 82 ENICDSNNKNDFDESKEAEGVWSPDIENSFNEALQLYPPCGRRKIVLSEEGKMYGRNELIARYIKMQTGKSRSRKQVSSHIQVLARRKSKEIQNQIQ----EKHTREQARQQLANMSSAQIVSDFKIKENLSLCNDNRNK---SPKFVDNNINSF--SNTQGISRFSSIHHPTPLVANSKLLDTSSFLLRPNQIPPIMACTNTHNMYLKNDSPNDLISHNHTPIPAMWNVPHMXXXXXXXXXXXXXGPHLYVGRSIATPKMRLLELSVFVEAKEYPVKIEKGFGMKNYCKHVFAHLNSTESSLGHPFLEHIEISQIWDKYPET-DGLKEYFERGPQDAFFMVKFWIDMNFDVLPQWNQLSTII--FEGVENVKSKLSTKICSFGRQVLERIEEQSPILENGISIYRFENVPMCDYMRKFIIKLSSLKEHSLMNSVLENFTILQTVTNAFTGEILLCIAFAMEVSISDQGSQYHIYKLIRN 1485
E + DS +K +AEGVWSPDIE SF EAL +YPPCGRRKI+LS+EGKMYGRNELIARYIK++TGK+R+RKQVSSHIQVLAR+K +EIQ I+ ++ +++A Q +A MSSAQIVS I L L R P F I + ++Q + F +P ++P PI T P P+ VP + GRSI T K+RL+E S F+E + P +Y KH+F H+ S P LE ++I QI+DK+PE GLKE F +GPQ+AFF+VKFW D+N ++ + +E EN+ STK+CSFG+QV+E++E + ENG +YR PMC+YM FI KL L E +MNSVLENFTIL VTN T E LLC+A EVS S+ G+Q+HIY+L+++
Sbjct: 2 ERMSDSADK---PIDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARKKVREIQAAIKVTSMDQTAKDKALQHMAAMSSAQIVSATAIHNKLGLPGIPRPTFPGGPGFWPGMIQTGQPGSSQDVKPFVQQAYP----------------IQPAVTAPIPGFEPTS-----------------APAPS---VP------------------AWQGRSIGTTKLRLVEFSAFLEQQRDP---------DSYNKHLFVHIGHANHSYSDPLLESVDIRQIYDKFPEKKGGLKELFGKGPQNAFFLVKFWADLNCNIQDDAGAFYGVSSQYESSENMTVTCSTKVCSFGKQVVEKVETEYARFENGRFVYRINRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILLVVTNRDTQETLLCMACVFEVSNSEHGAQHHIYRLVKD 415
BLAST of SD2 vs. Ensembl Mouse
Match: Tead1 (TEA domain family member 1 [Source:MGI Symbol;Acc:MGI:101876]) HSP 1 Score: 322.398 bits (825), Expect = 6.425e-104 Identity = 198/474 (41.77%), Postives = 274/474 (57.81%), Query Frame = 1
Query: 82 ENICDSNNKNDFDESKEAEGVWSPDIENSFNEALQLYPPCGRRKIVLSEEGKMYGRNELIARYIKMQTGKSRSRKQVSSHIQVLARRKSKEIQNQIQ-EKHTREQARQQLANMSSAQIVSDFKIKENLSLCNDNRNKSPKFVDNNINSFSNTQGISRFSSIHHPTPLVANSKLLDTSSFLLRPNQIPPIMACTNTHNMYLKNDSPNDLISHNHTPIPAMWNVPHMXXXXXXXXXXXXXGPHL--YVGRSIATPKMRLLELSVFVEAKEYPVKIEKGFGMKNYCKHVFAHLNSTESSLGHPFLEHIEISQIWDKYPET-DGLKEYFERGPQDAFFMVKFWIDMNFDVLPQWNQLSTII--FEGVENVKSKLSTKICSFGRQVLERIEEQSPILENGISIYRFENVPMCDYMRKFIIKLSSLKEHSLMNSVLENFTILQTVTNAFTGEILLCIAFAMEVSISDQGSQYHIYKLIRN 1485
E + DS +K +AEGVWSPDIE SF EAL +YPPCGRRKI+LS+EGKMYGRNELIARYIK++TGK+R+RKQVSSHIQVLAR+K +EIQ I+ H Q LA S S K+ S+ ++K+ + ++ + S+ Q +S ++IH+ L + +F P P ++ + S D+ P P ++ + +S P + + GRSI T K+RL+E S F+E + P +Y KH+F H+ S P LE ++I QI+DK+PE GLKE F +GPQ+AFF+VKFW D+N ++ + +E EN+ STK+CSFG+QV+E++E + ENG +YR PMC+YM FI KL L E +MNSVLENFTIL VTN T E LLC+A EVS S+ G+Q+HIY+L+++
Sbjct: 2 ERMSDSADK---PIDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARKKVREIQAAIKVSSHI-----QVLARRKSRDFHSKLKVT---SMDQTAKDKALQ----HMAAMSSAQIVSA-TAIHNKLGLPG----IPRPTFPGGPGFWPGMIQTG-------QPGSSQDVKPFVQQAYPIQ---PAVTAPIPGFEPTSAPAPSVPAWQGRSIGTTKLRLVEFSAFLEQQRDP---------DSYNKHLFVHIGHANHSYSDPLLESVDIRQIYDKFPEKKGGLKELFGKGPQNAFFLVKFWADLNCNIQDDAGAFYGVSSQYESSENMTVTCSTKVCSFGKQVVEKVETEYARFENGRFVYRINRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILLVVTNRDTQETLLCMACVFEVSNSEHGAQHHIYRLVKD 436
BLAST of SD2 vs. Ensembl Mouse
Match: Tead1 (TEA domain family member 1 [Source:MGI Symbol;Acc:MGI:101876]) HSP 1 Score: 322.398 bits (825), Expect = 6.425e-104 Identity = 198/474 (41.77%), Postives = 274/474 (57.81%), Query Frame = 1
Query: 82 ENICDSNNKNDFDESKEAEGVWSPDIENSFNEALQLYPPCGRRKIVLSEEGKMYGRNELIARYIKMQTGKSRSRKQVSSHIQVLARRKSKEIQNQIQ-EKHTREQARQQLANMSSAQIVSDFKIKENLSLCNDNRNKSPKFVDNNINSFSNTQGISRFSSIHHPTPLVANSKLLDTSSFLLRPNQIPPIMACTNTHNMYLKNDSPNDLISHNHTPIPAMWNVPHMXXXXXXXXXXXXXGPHL--YVGRSIATPKMRLLELSVFVEAKEYPVKIEKGFGMKNYCKHVFAHLNSTESSLGHPFLEHIEISQIWDKYPET-DGLKEYFERGPQDAFFMVKFWIDMNFDVLPQWNQLSTII--FEGVENVKSKLSTKICSFGRQVLERIEEQSPILENGISIYRFENVPMCDYMRKFIIKLSSLKEHSLMNSVLENFTILQTVTNAFTGEILLCIAFAMEVSISDQGSQYHIYKLIRN 1485
E + DS +K +AEGVWSPDIE SF EAL +YPPCGRRKI+LS+EGKMYGRNELIARYIK++TGK+R+RKQVSSHIQVLAR+K +EIQ I+ H Q LA S S K+ S+ ++K+ + ++ + S+ Q +S ++IH+ L + +F P P ++ + S D+ P P ++ + +S P + + GRSI T K+RL+E S F+E + P +Y KH+F H+ S P LE ++I QI+DK+PE GLKE F +GPQ+AFF+VKFW D+N ++ + +E EN+ STK+CSFG+QV+E++E + ENG +YR PMC+YM FI KL L E +MNSVLENFTIL VTN T E LLC+A EVS S+ G+Q+HIY+L+++
Sbjct: 2 ERMSDSADK---PIDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARKKVREIQAAIKVSSHI-----QVLARRKSRDFHSKLKVT---SMDQTAKDKALQ----HMAAMSSAQIVSA-TAIHNKLGLPG----IPRPTFPGGPGFWPGMIQTG-------QPGSSQDVKPFVQQAYPIQ---PAVTAPIPGFEPTSAPAPSVPAWQGRSIGTTKLRLVEFSAFLEQQRDP---------DSYNKHLFVHIGHANHSYSDPLLESVDIRQIYDKFPEKKGGLKELFGKGPQNAFFLVKFWADLNCNIQDDAGAFYGVSSQYESSENMTVTCSTKVCSFGKQVVEKVETEYARFENGRFVYRINRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILLVVTNRDTQETLLCMACVFEVSNSEHGAQHHIYRLVKD 436
BLAST of SD2 vs. UniProt/SwissProt
Match: sp|P48984|TEAD4_CHICK (Transcriptional enhancer factor TEF-3 OS=Gallus gallus OX=9031 GN=TEAD4 PE=2 SV=1) HSP 1 Score: 350.903 bits (899), Expect = 4.818e-114 Identity = 200/492 (40.65%), Postives = 273/492 (55.49%), Query Frame = 1
Query: 64 TTCSSNENICDSNNKNDFDE--SKEAEGVWSPDIENSFNEALQLYPPCGRRKIVLSEEGKMYGRNELIARYIKMQTGKSRSRKQVSSHIQVLARRKSKEIQNQIQ-------------EKHTREQARQQLANMSSAQIVSDFKIKENLSLCNDNRNKSPKFVDNNINSFSNTQGISRFSSIHHPTPLVANSKLLDTSSFLLRPNQIPPIMACTNTHNMYLKNDSPNDLISHNHTPIPAMWNVPHMXXXXXXXXXXXXXGPHLYVGRSIATPKMRLLELSVFVEAKEYPVKIEKGFGMKNYCKHVFAHLNSTESSLGHPFLEHIEISQIWDKYPET-DGLKEYFERGPQDAFFMVKFWIDMNFDVLPQWNQLSTII--FEGVENVKSKLSTKICSFGRQVLERIEEQSPILENGISIYRFENVPMCDYMRKFIIKLSSLKEHSLMNSVLENFTILQTVTNAFTGEILLCIAFAMEVSISDQGSQYHIYKLIRN 1485
++ +S E DS D+ +AEGVWSPDIE SF EAL +YPPCGRRKI+LS+EGKMYGRNELIARYIK++TGK+R+RKQVSSHIQVLARRK++EIQ +++ ++ +++A Q +A MSSAQI+S ++L R+ P + G S+ D F +P + P + DSP L + TP W GR +A+ K+ +LE S F+E ++ Y KH+F H+ + S P+LE ++I QI+DK+PE GLKE FERGP +AFF+VKFW D+N ++ + + +E EN+ STK+CSFG+QV+E++E + ENG YR P+C+YM FI KL L E +MNSVLENFTILQ VTN T E LLCIA+ EVS SD G+Q+HIY+L+++
Sbjct: 6 SSPASPEGSNDSGGSEALDKPIDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKAREIQAKLKKTQVDKYDFSSEKDQTAKDKAMQSIATMSSAQIISATAFHSKMALPGLPRSAYPAVSGFWQGALPGQAGSSQ-----------------DVKPFTQQPYALQPSLPLPGF-------DSPTGLPPSSSTP---AWQ-----------------------GRRVASSKLWMLEFSAFLEQQQ---------DQDTYNKHLFVHIGQSNPSYSDPYLEAVDIRQIYDKFPEKKGGLKELFERGPANAFFLVKFWADLNTNIEDESRSFYGVSSQYESPENMVITCSTKVCSFGKQVVEKVETEYAHYENGHYAYRIHRSPLCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTNRDTQETLLCIAYVFEVSASDHGAQHHIYRLVKD 438
BLAST of SD2 vs. UniProt/SwissProt
Match: sp|P30051|TEAD1_MOUSE (Transcriptional enhancer factor TEF-1 OS=Mus musculus OX=10090 GN=Tead1 PE=1 SV=2) HSP 1 Score: 345.125 bits (884), Expect = 5.240e-112 Identity = 202/483 (41.82%), Postives = 272/483 (56.31%), Query Frame = 1
Query: 61 STTCSSNENICDSNNKNDFDESKEAEGVWSPDIENSFNEALQLYPPCGRRKIVLSEEGKMYGRNELIARYIKMQTGKSRSRKQVSSHIQVLARRKSKEIQNQIQEKHTREQARQQLANMSSAQIVSDFKIKENLSLCNDNRNK---SPKFVDNNINSF--SNTQGISRFSSIHHPTPLVANSKLLDTSSFLLRPNQIPPIMACTNTHNMYLKNDSPNDLISHNHTPIPAMWNVPHMXXXXXXXXXXXXXGPHLYVGRSIATPKMRLLELSVFVEAKEYPVKIEKGFGMKNYCKHVFAHLNSTESSLGHPFLEHIEISQIWDKYPET-DGLKEYFERGPQDAFFMVKFWIDMNFDVLPQWNQLSTII--FEGVENVKSKLSTKICSFGRQVLERIEEQSPILENGISIYRFENVPMCDYMRKFIIKLSSLKEHSLMNSVLENFTILQTVTNAFTGEILLCIAFAMEVSISDQGSQYHIYKLIRN 1485
S + S EN+ ++ D +AEGVWSPDIE SF EAL +YPPCGRRKI+LS+EGKMYGRNELIARYIK++TGK+R+RKQVSSHIQVLARRKS++ ++++++ +++A Q +A MSSAQIVS I L L R P F I + ++Q + F +P ++P PI T P P+ VP + GRSI T K+RL+E S F+E + P +Y KH+F H+ S P LE ++I QI+DK+PE GLKE F +GPQ+AFF+VKFW D+N ++ + +E EN+ STK+CSFG+QV+E++E + ENG +YR PMC+YM FI KL L E +MNSVLENFTIL VTN T E LLC+A EVS S+ G+Q+HIY+L+++
Sbjct: 7 SGSESPAENMERMSDSADKPIDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSRDFHSKLKDQTAKDKALQHMAAMSSAQIVSATAIHNKLGLPGIPRPTFPGGPGFWPGMIQTGQPGSSQDVKPFVQQAYP----------------IQPAVTAPIPGFEPTS-----------------APAPS---VP------------------AWQGRSIGTTKLRLVEFSAFLEQQRDP---------DSYNKHLFVHIGHANHSYSDPLLESVDIRQIYDKFPEKKGGLKELFGKGPQNAFFLVKFWADLNCNIQDDAGAFYGVSSQYESSENMTVTCSTKVCSFGKQVVEKVETEYARFENGRFVYRINRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILLVVTNRDTQETLLCMACVFEVSNSEHGAQHHIYRLVKD 426
BLAST of SD2 vs. UniProt/SwissProt
Match: sp|Q90701|TEAD3_CHICK (Transcriptional enhancer factor TEF-5 OS=Gallus gallus OX=9031 GN=TEAD3 PE=2 SV=2) HSP 1 Score: 337.035 bits (863), Expect = 9.720e-109 Identity = 201/485 (41.44%), Postives = 277/485 (57.11%), Query Frame = 1
Query: 94 DSNNKNDFDESKEAEGVWSPDIENSFNEALQLYPPCGRRKIVLSEEGKMYGRNELIARYIKMQTGKSRSRKQVSSHIQVLARRK----SKEIQNQIQEKHTREQARQQLANMSSAQIVSDFKIKENLS----LCNDNRNKSPKFVDNNI-NSFSNTQGISRFSSIHHPTPLVANSKLLDTSSFLLRPNQIPPIMACTNTHNMYLKNDSPNDLISHNHTPI----PAMWNVPHMXXXXXXXXXXXXXGPHLYVGRSIATPKMRLLELSVFVEAKEYPVKIEKGFGMKNYCKHVFAHLNSTESSLGHPFLEHIEISQIWDKYPET-DGLKEYFERGPQDAFFMVKFWIDMNFDVLPQWNQLSTIIFEGV-------ENVKSKLSTKICSFGRQVLERIEEQSPILENGISIYRFENVPMCDYMRKFIIKLSSLKEHSLMNSVLENFTILQTVTNAFTGEILLCIAFAMEVSISDQGSQYHIYKLIRN 1485
D + D +AEGVWSPDIE SF EAL +YPPCGRRKI+LS+EGKMYGRNELIARYIK++TGK+R++KQVSSH+QVLARR+ S +++ ++ ++++A Q +A+MSSAQIVS ++ LS L + +P+F I +Q I F+ +P ++P +PP +A ++ P+ PA VP ++ R+IA+ K+RLLE S F+E + Y KH+F H+ T S P LE ++I QI+DK+PE GLKE +ERGPQ++FF++KFW D+N + Q F GV EN+ +STK+CSFG+QV+E++E + LEN +YR PMC+YM FI KL L E +MNSVLENFTILQ VTN T E LLCIAF EVS S+ G+Q+H+YKL+++
Sbjct: 18 DGQDGMDKSLDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTKKQVSSHLQVLARREISGDSSKLKAMNLDQVSKDKAFQSMASMSSAQIVSASVLQNKLSPPPPLPQAVFSAAPRFWSGPIPGQPGPSQDIKPFAQPAYP----------------IQP-PMPPSLA--------------------SYEPLAPLPPAASAVP------------------VWQDRTIASAKLRLLEYSAFMEVPR---------DAETYSKHLFVHIGQTNPSYSDPLLEAMDIRQIYDKFPEKKGGLKELYERGPQNSFFLLKFWADLNSTI-----QDGPGTFYGVSSQYSSAENMTITVSTKVCSFGKQVVEKVETEYARLENSRFVYRIHRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTNRDTQETLLCIAFVFEVSTSEHGAQHHVYKLVKD 433
BLAST of SD2 vs. UniProt/SwissProt
Match: sp|Q99594|TEAD3_HUMAN (Transcriptional enhancer factor TEF-5 OS=Homo sapiens OX=9606 GN=TEAD3 PE=1 SV=2) HSP 1 Score: 331.643 bits (849), Expect = 1.248e-106 Identity = 197/470 (41.91%), Postives = 275/470 (58.51%), Query Frame = 1
Query: 130 EAEGVWSPDIENSFNEALQLYPPCGRRKIVLSEEGKMYGRNELIARYIKMQTGKSRSRKQVSSHIQVLARRKSKEIQNQIQ----EKHTREQARQQLANMSSAQIVSDFKIKENLSLCNDNRNKSPKFVDNNINSFSNTQGISRFSSI-----HHPTPLVANSKLLDTSSFLLRPNQIPPIMACTNTHNMYLKNDSPNDLISHNHTPIP-AMWNVPHMXXXXXXXXXXXXXGPHLYVGRSIATPKMRLLELSVFVEAKEYPVKIEKGFGMKNYCKHVFAHLNSTESSLGHPFLEHIEISQIWDKYPET-DGLKEYFERGPQDAFFMVKFWIDMNFDVLPQWNQLSTIIFEGV-------ENVKSKLSTKICSFGRQVLERIEEQSPILENGISIYRFENVPMCDYMRKFIIKLSSLKEHSLMNSVLENFTILQTVTNAFTGEILLCIAFAMEVSISDQGSQYHIYKLIRN 1485
+AEGVWSPDIE SF EAL +YPPCGRRKI+LS+EGKMYGRNELIARYIK++TGK+R+RKQVSSHIQVLAR+K +E Q I+ ++ ++++A Q +A+MSSAQIVS ++ N+ P + + S S SRF S P P + K ++ ++P +PP ++ P+P A +VP ++ R+IA+ ++RLLE S F+E + P Y KH+F H+ T + P LE +++ QI+DK+PE GLKE +E+GP +AFF+VKFW D+N + Q F GV +++ +STK+CSFG+QV+E++E + LENG +YR PMC+YM FI KL L E +MNSVLENFTILQ VT+ + E LL IAF EVS S+ G+Q+H+YKL+++
Sbjct: 30 DAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARKKVREYQVGIKAMNLDQVSKDKALQSMASMSSAQIVSASVLQ--------NKFSPPSPLPQAVFSTS-----SRFWSSPPLLGQQPGP-SQDIKPFAQPAYPIQPP-LPPTLSSYEPL-----------------APLPSAAASVP------------------VWQDRTIASSRLRLLEYSAFMEVQRDP---------DTYSKHLFVHIGQTNPAFSDPPLEAVDVRQIYDKFPEKKGGLKELYEKGPPNAFFLVKFWADLNSTI-----QEGPGAFYGVSSQYSSADSMTISVSTKVCSFGKQVVEKVETEYARLENGRFVYRIHRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTSRDSQETLLVIAFVFEVSTSEHGAQHHVYKLVKD 435
BLAST of SD2 vs. UniProt/SwissProt
Match: sp|Q62296|TEAD4_MOUSE (Transcriptional enhancer factor TEF-3 OS=Mus musculus OX=10090 GN=Tead4 PE=1 SV=2) HSP 1 Score: 310.842 bits (795), Expect = 1.014e-98 Identity = 185/454 (40.75%), Postives = 262/454 (57.71%), Query Frame = 1
Query: 130 EAEGVWSPDIENSFNEALQLYPPCGRRKIVLSEEGKMYGRNELIARYIKMQTGKSRSRKQVSSHIQVLARRKSKEIQNQIQEKHTREQARQQLANMSSAQIVSDFKIKENLSLCNDNRNKSPKFVDNNINSFSNTQGISRFSSIHHPTPLVANSKLLDTSSFLLRPNQIPPIMACTNTHNMYLKNDSPNDLISHNHTPIPAMWNVPHMXXXXXXXXXXXXXGPHLYVGRSIATPKMRLLELSVFVEAKEYPVKIEKGFGMKNYCKHVFAHLNSTESSLGHPFLEHIEISQIWDKYPET-DGLKEYFERGPQDAFFMVKFWIDMNFDVLPQWNQLSTII--FEGVENVKSKLSTKICSFGRQVLERIEEQSPILENGISIYRFENVPMCDYMRKFIIKLSSLKEHSLMNSVLENFTILQTVTNAFTGEILLCIAFAMEVSISDQGSQYHIYKLIR 1482
+AEGVWSP+IE SF EAL +YPPCGRRKI+L+EEGKMYGRNELIAR+IK++TGK+R+RKQVSSHIQVLA R +AR+ A K+K+ + +NK+ + ++ + S+ Q +S ++ H L S F +P ++ + +N P P+P +P + + S + GRSIA+ K+ +LE S F+E ++ P Y KH+F H++ + S P+LE ++I QI+DK+PE GLKE FERGP +AFF+VKFW D+N ++ + + + +E EN+ STK+CSFG+QV+E++E + ENG +YR P+C+YM FI KL L E +MNSVLENFTILQ VTN T E LLCIA+ EVS S+ G+Q+HIY+L++
Sbjct: 31 DAEGVWSPEIERSFQEALAIYPPCGRRKIILTEEGKMYGRNELIARHIKLRTGKTRTRKQVSSHIQVLA----------------RRKAREIQA-----------KLKDQAA-----KNKALQ----SMAAMSSAQIVSA-TAFHSKMALARGPGYPAISGFWQ--GALPGQPGTSHDVKPFSQNTYPV------QPPLP----LPGFESPAGPTPSPSAPLAPPWQGRSIASSKLWMLEFSAFLERQQDP---------DTYNKHLFVHISQSSPSYSDPYLETVDIRQIYDKFPEKKGGLKELFERGPSNAFFLVKFWADLNTNIDDEGSAFYGVSSQYESPENMIITCSTKVCSFGKQVVEKVETEYARYENGHYLYRIHRSPLCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTNRDTQETLLCIAYVFEVSASEHGAQHHIYRLVK 426
BLAST of SD2 vs. TrEMBL
Match: W8E1N4 (SD2 OS=Schmidtea mediterranea OX=79327 GN=sd2 PE=2 SV=1) HSP 1 Score: 990.334 bits (2559), Expect = 0.000e+0 Identity = 489/489 (100.00%), Postives = 489/489 (100.00%), Query Frame = 1
Query: 52 MECSTTCSSNENICDSNNKNDFDESKEAEGVWSPDIENSFNEALQLYPPCGRRKIVLSEEGKMYGRNELIARYIKMQTGKSRSRKQVSSHIQVLARRKSKEIQNQIQEKHTREQARQQLANMSSAQIVSDFKIKENLSLCNDNRNKSPKFVDNNINSFSNTQGISRFSSIHHPTPLVANSKLLDTSSFLLRPNQIPPIMACTNTHNMYLKNDSPNDLISHNHTPIPAMWNVPHMXXXXXXXXXXXXXGPHLYVGRSIATPKMRLLELSVFVEAKEYPVKIEKGFGMKNYCKHVFAHLNSTESSLGHPFLEHIEISQIWDKYPETDGLKEYFERGPQDAFFMVKFWIDMNFDVLPQWNQLSTIIFEGVENVKSKLSTKICSFGRQVLERIEEQSPILENGISIYRFENVPMCDYMRKFIIKLSSLKEHSLMNSVLENFTILQTVTNAFTGEILLCIAFAMEVSISDQGSQYHIYKLIRNSNLPTLSNFSN 1518
MECSTTCSSNENICDSNNKNDFDESKEAEGVWSPDIENSFNEALQLYPPCGRRKIVLSEEGKMYGRNELIARYIKMQTGKSRSRKQVSSHIQVLARRKSKEIQNQIQEKHTREQARQQLANMSSAQIVSDFKIKENLSLCNDNRNKSPKFVDNNINSFSNTQGISRFSSIHHPTPLVANSKLLDTSSFLLRPNQIPPIMACTNTHNMYLKNDSPNDLISHNHTPIPAMWNVPHMSRASSLSDQSSLLGPHLYVGRSIATPKMRLLELSVFVEAKEYPVKIEKGFGMKNYCKHVFAHLNSTESSLGHPFLEHIEISQIWDKYPETDGLKEYFERGPQDAFFMVKFWIDMNFDVLPQWNQLSTIIFEGVENVKSKLSTKICSFGRQVLERIEEQSPILENGISIYRFENVPMCDYMRKFIIKLSSLKEHSLMNSVLENFTILQTVTNAFTGEILLCIAFAMEVSISDQGSQYHIYKLIRNSNLPTLSNFSN
Sbjct: 1 MECSTTCSSNENICDSNNKNDFDESKEAEGVWSPDIENSFNEALQLYPPCGRRKIVLSEEGKMYGRNELIARYIKMQTGKSRSRKQVSSHIQVLARRKSKEIQNQIQEKHTREQARQQLANMSSAQIVSDFKIKENLSLCNDNRNKSPKFVDNNINSFSNTQGISRFSSIHHPTPLVANSKLLDTSSFLLRPNQIPPIMACTNTHNMYLKNDSPNDLISHNHTPIPAMWNVPHMSRASSLSDQSSLLGPHLYVGRSIATPKMRLLELSVFVEAKEYPVKIEKGFGMKNYCKHVFAHLNSTESSLGHPFLEHIEISQIWDKYPETDGLKEYFERGPQDAFFMVKFWIDMNFDVLPQWNQLSTIIFEGVENVKSKLSTKICSFGRQVLERIEEQSPILENGISIYRFENVPMCDYMRKFIIKLSSLKEHSLMNSVLENFTILQTVTNAFTGEILLCIAFAMEVSISDQGSQYHIYKLIRNSNLPTLSNFSN 489
BLAST of SD2 vs. TrEMBL
Match: A0A3Q3IC19 (TEA domain family member 3 b OS=Monopterus albus OX=43700 PE=4 SV=1) HSP 1 Score: 364.385 bits (934), Expect = 5.622e-117 Identity = 207/461 (44.90%), Postives = 280/461 (60.74%), Query Frame = 1
Query: 130 EAEGVWSPDIENSFNEALQLYPPCGRRKIVLSEEGKMYGRNELIARYIKMQTGKSRSRKQVSSHIQVLARRKSKEIQNQIQEKHTREQARQQLANMSSAQIVSDFKIKENLS-LCNDNRNKSPKFVDNNINSFSNTQGISRFSSIHHPTPLVANSKLLDTSSFLLRPNQIPPIMACTNTHNMYLKNDSPNDLISHNHTPIPAMWNVPHMXXXXXXXXXXXXXGPHLYVGRSIATPKMRLLELSVFVEAKEYPVKIEKGFGMKNYCKHVFAHLNSTESSLGHPFLEHIEISQIWDKYPET-DGLKEYFERGPQDAFFMVKFWIDMNFDVLPQWNQLSTIIFEGV-------ENVKSKLSTKICSFGRQVLERIEEQSPILENGISIYRFENVPMCDYMRKFIIKLSSLKEHSLMNSVLENFTILQTVTNAFTGEILLCIAFAMEVSISDQGSQYHIYKLIRN 1485
+AEGVWSPDIE SF EAL +YPPCGRRKI+LS+EGKMYGRNELIARYIK++TGK+R+RKQVSSHIQVLAR+K +E Q I+++ T+++A Q +A +SSAQIVS IK +L L +PKF I+ P P + +LD L P + P ++ +++ P+ H P+P ++P ++ P ++ R+IA+ K+R+LE S F+E + P NY KH+F H+ T S P LE ++I QI+DK+PE GLKE +E+GPQ+AFF+VKFW D+N + Q F GV EN+ +STK+CSFG+QV+E++E + LE G +YR PMC+YM FI KL L E +MNSVLENFTILQ VTN T E LLCIAF EVS S+ G+QYH+Y+L+++
Sbjct: 4 DAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARKKVREYQAGIKDQATKDKALQNMAALSSAQIVSPSMIKNHLPPLPPAPYQAAPKFWPAPISG--------------QPGP--SQELVLD-----LNPGRTPGFGHTSHAIKPFVQPPYPS---LHIQGPVPQ--SIPSYEPLVPPPAPNATAVP-VWQDRTIASSKLRMLEYSAFMEVQRDP---------DNYSKHLFVHIGQTNPSYSDPLLEAVDIRQIYDKFPEKKGGLKELYEKGPQNAFFLVKFWADLNSSGM----QDGPGSFYGVSSQYSSTENMTITVSTKVCSFGKQVVEKVETEYARLEGGKCVYRIHRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTNRDTQETLLCIAFVFEVSTSEHGAQYHVYRLVKD 424
BLAST of SD2 vs. TrEMBL
Match: A0A091W6Q0 (Transcriptional enhancer factor TEF-5 (Fragment) OS=Nipponia nippon OX=128390 GN=Y956_10885 PE=4 SV=1) HSP 1 Score: 363.999 bits (933), Expect = 8.470e-117 Identity = 211/491 (42.97%), Postives = 287/491 (58.45%), Query Frame = 1
Query: 64 TTCSSNENICDSNNKNDFDESKEAEGVWSPDIENSFNEALQLYPPCGRRKIVLSEEGKMYGRNELIARYIKMQTGKSRSRKQVSSHIQVLARRKSKEIQNQIQEKHTREQARQQLANMSSAQIVSDFKIKENLS----LCNDNRNKSPKFVDNNI-NSFSNTQGISRFSSIHHPTPLVANSKLLDTSSFLLRPNQIPPIMACTNTHNMYLKNDSPNDLISHNHTPI----PAMWNVPHMXXXXXXXXXXXXXGPHLYVGRSIATPKMRLLELSVFVEAKEYPVKIEKGFGMKNYCKHVFAHLNSTESSLGHPFLEHIEISQIWDKYPET-DGLKEYFERGPQDAFFMVKFWIDMNFDVLPQWNQLSTIIFEGV-------ENVKSKLSTKICSFGRQVLERIEEQSPILENGISIYRFENVPMCDYMRKFIIKLSSLKEHSLMNSVLENFTILQTVTNAFTGEILLCIAFAMEVSISDQGSQYHIYKLIRN 1485
T+ S E D + D +AEGVWSPDIE SF EAL +YPPCGRRKI+LS+EGKMYGRNELIARYIK++TGK+R+RKQVSSH+QVLARRKS+EIQ++++++ ++++A Q +A+MSSAQIVS ++ LS L + +P+F I +Q I F+ +P ++P +PP +A ++ P+ PA VP ++ R+IA+ K+RLLE S F+E + Y KH+F H+ T S P LE ++I QI+DK+PE GLKE +ERGPQ++FF+VKFW D+N + Q F GV EN+ +STK+CSFG+QV+E++E + LENG +YR PMC+YM FI KL L E +MNSVLENFTILQ VTN T E LLCIAF EVS S+ G+Q+H+YKL+++
Sbjct: 8 TSGSPGEGREDGQDGMDKSLDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHLQVLARRKSREIQSKLKDQVSKDKALQSMASMSSAQIVSASVLQNKLSPPPPLPQAVFSAAPRFWSGPIPGQPGPSQDIKPFAQPAYP----------------IQP-PMPPSLA--------------------SYEPLAPLPPAASAVP------------------VWQDRTIASTKLRLLEYSAFMEVPR---------DTETYSKHLFVHIGQTNPSYSDPLLEAVDIRQIYDKFPEKKGGLKELYERGPQNSFFLVKFWADLNSTI-----QDGPGTFYGVSSQYSSAENMTITVSTKVCSFGKQVVEKVETEYARLENGRFVYRIHRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTNRDTQETLLCIAFVFEVSTSEHGAQHHVYKLVKD 429
BLAST of SD2 vs. TrEMBL
Match: A0A402EJX0 (Transcriptional enhancer factor TEF-5 OS=Paroedura picta OX=143630 GN=parPi_0003834 PE=4 SV=1) HSP 1 Score: 362.844 bits (930), Expect = 1.036e-116 Identity = 207/469 (44.14%), Postives = 283/469 (60.34%), Query Frame = 1
Query: 130 EAEGVWSPDIENSFNEALQLYPPCGRRKIVLSEEGKMYGRNELIARYIKMQTGKSRSRKQVSSHIQVLARRKSKEIQNQIQEKHTREQARQQLANMSSAQIVSDFKIKENLS----LCNDNRNKSPKFVDNNINSFSN-TQGISRFSSIHHPTPLVANSKLLDTSSFLLRPNQIPPIMACTNTHNMYLKNDSPNDLISHNHTPI----PAMWNVPHMXXXXXXXXXXXXXGPHLYVGRSIATPKMRLLELSVFVEAKEYPVKIEKGFGMKNYCKHVFAHLNSTESSLGHPFLEHIEISQIWDKYPET-DGLKEYFERGPQDAFFMVKFWIDMNFDVLPQWNQLSTIIFEGV-------ENVKSKLSTKICSFGRQVLERIEEQSPILENGISIYRFENVPMCDYMRKFIIKLSSLKEHSLMNSVLENFTILQTVTNAFTGEILLCIAFAMEVSISDQGSQYHIYKLIRN 1485
+AEGVWSPDIE SF EAL +YPPCGRRKI+LS+EGKMYGRNELIARYIK++TGK+R+RKQVSSH+QVLARRKS+EIQ++++++ ++++A Q +A+MSSAQIVS ++ LS L + +P+F I S +Q I F+ +P ++P +PP +A ++ P+ PA VP ++ R+IA+ K+RLLE S F+E + P + Y KH+F H+ T S P LE ++I QI+DK+PE GLKE +ERGPQ++FF+VKFW D+N + Q F GV EN+ +STK+CSFG+QV+E++E + +ENG +YR PMC+YM FI KL L E +MNSVLENFTILQ VTN T E LLCIAF EVS S+ G+Q+H+YKL+++
Sbjct: 8 DAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHLQVLARRKSREIQSKLKDQVSKDKALQSMASMSSAQIVSASVLQNKLSPPPPLPQAVFSAAPRFWSGPIPGQSGPSQDIKPFTQPAYP----------------IQPP-MPPSLA--------------------SYEPLAPLPPAASAVP------------------VWQDRTIASTKLRLLEYSAFMEVQRDP---------ETYSKHLFVHIGQTNPSYSDPLLEAVDIRQIYDKFPEKKGGLKELYERGPQNSFFLVKFWADLNSTI-----QDGPGAFYGVSSQYSSAENMTITVSTKVCSFGKQVVEKVETEYARMENGRFVYRIHRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTNRDTQETLLCIAFVFEVSTSEHGAQHHVYKLVKD 407
BLAST of SD2 vs. TrEMBL
Match: R7VN85 (Transcriptional enhancer factor TEF-5 (Fragment) OS=Columba livia OX=8932 GN=A306_14720 PE=4 SV=1) HSP 1 Score: 363.614 bits (932), Expect = 2.157e-116 Identity = 210/491 (42.77%), Postives = 287/491 (58.45%), Query Frame = 1
Query: 64 TTCSSNENICDSNNKNDFDESKEAEGVWSPDIENSFNEALQLYPPCGRRKIVLSEEGKMYGRNELIARYIKMQTGKSRSRKQVSSHIQVLARRKSKEIQNQIQEKHTREQARQQLANMSSAQIVSDFKIKENLS----LCNDNRNKSPKFVDNNI-NSFSNTQGISRFSSIHHPTPLVANSKLLDTSSFLLRPNQIPPIMACTNTHNMYLKNDSPNDLISHNHTPI----PAMWNVPHMXXXXXXXXXXXXXGPHLYVGRSIATPKMRLLELSVFVEAKEYPVKIEKGFGMKNYCKHVFAHLNSTESSLGHPFLEHIEISQIWDKYPET-DGLKEYFERGPQDAFFMVKFWIDMNFDVLPQWNQLSTIIFEGV-------ENVKSKLSTKICSFGRQVLERIEEQSPILENGISIYRFENVPMCDYMRKFIIKLSSLKEHSLMNSVLENFTILQTVTNAFTGEILLCIAFAMEVSISDQGSQYHIYKLIRN 1485
+ S E D + D +AEGVWSPDIE SF EAL +YPPCGRRKI+LS+EGKMYGRNELIARYIK++TGK+R+RKQVSSH+QVLARRKS+EIQ++++++ ++++A Q +A+MSSAQIVS ++ LS L + +P+F I +Q I F+ +P ++P+ +PP +A ++ P+ PA VP ++ R+IA+ K+RLLE S F+E + Y KH+F H+ T S P LE ++I QI+DK+PE GLKE +ERGPQ++FF+VKFW D+N + Q F GV EN+ +STK+CSFG+QV+E++E + LENG +YR PMC+YM FI KL L E +MNSVLENFTILQ VTN T E LLCIAF EVS S+ G+Q+H+YKL+++
Sbjct: 25 ASGSPGEGREDGQDGMDKSLDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHLQVLARRKSREIQSKLKDQVSKDKALQSMASMSSAQIVSASVLQNKLSPPPPLPQAVFSAAPRFWSGPIPGQPGPSQDIKPFAQPAYP----------------IQPH-MPPSLA--------------------SYEPLAPLPPAASAVP------------------VWQDRTIASAKLRLLEYSAFMEVPR---------DAETYSKHLFVHIGQTNPSYSDPLLEAVDIRQIYDKFPEKKGGLKELYERGPQNSFFLVKFWADLNSTI-----QDGPGTFYGVSSQYSSAENMTITVSTKVCSFGKQVVEKVETEYARLENGRFVYRIHRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTNRDTQETLLCIAFVFEVSTSEHGAQHHVYKLVKD 446
BLAST of SD2 vs. Ensembl Cavefish
Match: ENSAMXT00000015527.2 (pep primary_assembly:Astyanax_mexicanus-2.0:8:25794338:25829633:1 gene:ENSAMXG00000015088.2 transcript:ENSAMXT00000015527.2 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 349.362 bits (895), Expect = 1.221e-114 Identity = 197/460 (42.83%), Postives = 274/460 (59.57%), Query Frame = 1
Query: 130 EAEGVWSPDIENSFNEALQLYPPCGRRKIVLSEEGKMYGRNELIARYIKMQTGKSRSRKQVSSHIQVLARRKSKEIQNQIQEKHTREQARQQLANMSSAQIVSDFKIKENLSLCNDNRNKSPKFVDNNINSFSNTQGISRFSSIHHPTPLVANSKLLDTSSFLLRPNQIPPIMACTNTHNMYLKNDSPNDLISHNHTPIPAMWNVPHMXXXXXXXXXXXXXGPHLYVGRSIATPKMRLLELSVFVEAKEYPVKIEKGFGMKNYCKHVFAHLNSTESSLGHPFLEHIEISQIWDKYPET-DGLKEYFERGPQDAFFMVKFWIDMNFDVLPQWNQLSTIIFEGV-------ENVKSKLSTKICSFGRQVLERIEEQSPILENGISIYRFENVPMCDYMRKFIIKLSSLKEHSLMNSVLENFTILQTVTNAFTGEILLCIAFAMEVSISDQGSQYHIYKLIRN 1485
+AEGVWSPDIE SF EAL +YPPCGRRKI+LS+EGKMYGRNELIARYIK++TGK+R+RKQVSSHIQVLARRK++EIQ +++++ +++A Q +A MSSAQI+S + ++L QG+SR P V F RP I P + N ++ P PI + +S + S + GRSIA+ K+R+LE S F+E + P +N+ KH+F H+ + + P+LE ++I QI+DK+PE GLKE FE+GP +AFF+VKFW D++ ++ Q + F GV +N+ STK+CSFG+QV+E++E + ENG ++R P+C+YM FI KL L E +MNSVLENFTILQ VTN T E LLC+A+ EVS S+ G+Q+HIY+L+++
Sbjct: 40 DAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKAREIQVKLKDQAAKDKALQNMATMSSAQIISATAFQNKMAL----------------------QGLSR--------PAV----------FFFRPFSIKPF----SQQNYVMQATGP---------PITGYESASGLSMSPSAPP---------WQGRSIASSKLRMLEFSAFLEQPQDP---------ENFNKHLFVHIGQSNPTYSDPYLEAVDIRQIYDKFPEKKGGLKELFEKGPANAFFLVKFWADLSVNL-----QDDSSFFYGVSSQYESSDNMIITSSTKVCSFGKQVVEKVETEYARFENGRYVFRIHRSPLCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTNRDTLETLLCVAYVFEVSTSEHGAQHHIYRLVKD 423
BLAST of SD2 vs. Ensembl Cavefish
Match: tead1a (transcriptional enhancer factor TEF-1-like [Source:NCBI gene;Acc:103024231]) HSP 1 Score: 338.961 bits (868), Expect = 1.309e-110 Identity = 192/473 (40.59%), Postives = 266/473 (56.24%), Query Frame = 1
Query: 82 ENICDSNNKNDFDESKEAEGVWSPDIENSFNEALQLYPPCGRRKIVLSEEGKMYGRNELIARYIKMQTGKSRSRKQVSSHIQVLARRKSKEIQNQIQEKHTREQARQQLANMSSAQIVSDFKIKENLSLCN---DNRNKSPKFVDNNINSFSNTQGISRFSSIHHPTPLVANSKLLDTSSFLLRPNQIPPIMACTNTHNMYLKNDSPNDLISHNHTPIPAMWNVPHMXXXXXXXXXXXXXGPHLYVGRSIATPKMRLLELSVFVEAKEYPVKIEKGFGMKNYCKHVFAHLNSTESSLGHPFLEHIEISQIWDKYPET-DGLKEYFERGPQDAFFMVKFWIDMNFDVLPQWNQLSTII--FEGVENVKSKLSTKICSFGRQVLERIEEQSPILENGISIYRFENVPMCDYMRKFIIKLSSLKEHSLMNSVLENFTILQTVTNAFTGEILLCIAFAMEVSISDQGSQYHIYKLIR 1482
E + DS +K +AEGVWSPDIE SF EAL +YPPCGRRKI+LS+EGKMYGRNELIARYIK++TGK+R+RKQVSSHIQVLARRKS+E+ +++++ +++A Q +A MSSAQIVS I L L + +P F + ++Q + F+ +P + T+ P +P P W GRSI T K+RL+E S F+E + P ++Y KH+F H+ T P LE ++I QI+DK+PE GLK+ F +GPQ+AFF+VKFW D+N ++ + +E +N+ STK+CSFG+QV+E++E + +NG +Y+ PMC+YM FI KL L E +MNSVLENFTIL V+N T E LLC+A EVS S+ G+Q+HIY+L++
Sbjct: 17 ERMSDSADK---PMDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSRELHAKLKDQSVKDKALQSMAAMSSAQIVSATAIHNKLGLAGLPQPSFPGAPGFWQLSTGHPGSSQDVKPFAQQAYP---------IQTALSGFEPPSVP--------------------------AATPPAWQ-----------------------GRSIGTTKLRLVEFSSFLEQQRDP---------ESYNKHLFVHIGQTNHLHSDPLLESVDIRQIYDKFPEKKGGLKDLFAKGPQNAFFLVKFWADLNCNLQEDSGAFYGVTSQYESPDNMTITCSTKVCSFGKQVVEKVETEYARFDNGRFVYKINRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILLVVSNRETQETLLCMACVFEVSNSEHGAQHHIYRLVK 419
BLAST of SD2 vs. Ensembl Cavefish
Match: tead1a (transcriptional enhancer factor TEF-1-like [Source:NCBI gene;Acc:103024231]) HSP 1 Score: 334.724 bits (857), Expect = 7.057e-109 Identity = 193/477 (40.46%), Postives = 265/477 (55.56%), Query Frame = 1
Query: 82 ENICDSNNKNDFDESKEAEGVWSPDIENSFNEALQLYPPCGRRKIVLSEEGKMYGRNELIARYIKMQTGKSRSRKQVSSHIQVLARRKSKEIQNQIQEKH----TREQARQQLANMSSAQIVSDFKIKENLSLCN---DNRNKSPKFVDNNINSFSNTQGISRFSSIHHPTPLVANSKLLDTSSFLLRPNQIPPIMACTNTHNMYLKNDSPNDLISHNHTPIPAMWNVPHMXXXXXXXXXXXXXGPHLYVGRSIATPKMRLLELSVFVEAKEYPVKIEKGFGMKNYCKHVFAHLNSTESSLGHPFLEHIEISQIWDKYPET-DGLKEYFERGPQDAFFMVKFWIDMNFDVLPQWNQLSTII--FEGVENVKSKLSTKICSFGRQVLERIEEQSPILENGISIYRFENVPMCDYMRKFIIKLSSLKEHSLMNSVLENFTILQTVTNAFTGEILLCIAFAMEVSISDQGSQYHIYKLIR 1482
E + DS +K +AEGVWSPDIE SF EAL +YPPCGRRKI+LS+EGKMYGRNELIARYIK++TGK+R+RKQVSSHIQVLARRKS+E+ +++ H +++A Q +A MSSAQIVS I L L + +P F + ++Q + F+ +P + T+ P +P P W GRSI T K+RL+E S F+E + P ++Y KH+F H+ T P LE ++I QI+DK+PE GLK+ F +GPQ+AFF+VKFW D+N ++ + +E +N+ STK+CSFG+QV+E++E + +NG +Y+ PMC+YM FI KL L E +MNSVLENFTIL V+N T E LLC+A EVS S+ G+Q+HIY+L++
Sbjct: 17 ERMSDSADK---PMDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSRELHAKLKVTHLDQSVKDKALQSMAAMSSAQIVSATAIHNKLGLAGLPQPSFPGAPGFWQLSTGHPGSSQDVKPFAQQAYP---------IQTALSGFEPPSVP--------------------------AATPPAWQ-----------------------GRSIGTTKLRLVEFSSFLEQQRDP---------ESYNKHLFVHIGQTNHLHSDPLLESVDIRQIYDKFPEKKGGLKDLFAKGPQNAFFLVKFWADLNCNLQEDSGAFYGVTSQYESPDNMTITCSTKVCSFGKQVVEKVETEYARFDNGRFVYKINRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILLVVSNRETQETLLCMACVFEVSNSEHGAQHHIYRLVK 423
BLAST of SD2 vs. Ensembl Cavefish
Match: tead3b (TEA domain transcription factor 3 [Source:NCBI gene;Acc:103042642]) HSP 1 Score: 328.176 bits (840), Expect = 1.252e-106 Identity = 197/472 (41.74%), Postives = 260/472 (55.08%), Query Frame = 1
Query: 130 EAEGVWSPDIENSFNEALQLYPPCGRRKIVLSEEGKMYGRNELIARYIKMQTGKSRSRKQVSSHIQVLARRKSKEIQNQIQEKHTREQARQQLANMSSAQIVSDFKIKENLSLCNDNRNKSPKFVDNNINSFSNTQGI-------SRFSSIHHPTPLVANSKLLDTSSFLLRPNQIPPIMACTNTHNMYLKNDSPNDLISHNHTPI-----PAMWNVPHMXXXXXXXXXXXXXGPHLYVGRSIATPKMRLLELSVFVEAKEYPVKIEKGFGMKNYCKHVFAHLNSTESSLGHPFLEHIEISQIWDKYPET-DGLKEYFERGPQDAFFMVKFWIDMNFDVLPQWNQLSTIIFEGV-------ENVKSKLSTKICSFGRQVLERIEEQSPILENGISIYRFENVPMCDYMRKFIIKLSSLKEHSLMNSVLENFTILQTVTNAFTGEILLCIAFAMEVSISDQGSQYHIYKLIRN 1485
+AEGVWSPDIE SF EAL +YPPCGRRKI+LS+EGKMYGRNELIARYIK++TGK+R+RKQVSSH+QVLARRKS+EIQ++ L M+ Q D K +N++ + + SP + + + SRF PTP+ P Q P Y P + P+ P+ VP ++ R+IA+ K+R+LE S F+E +Y KH+F H+ T S P LE ++I QI+DK+PE GLKE +E+GPQ+AFF+VKFW D+N + Q F GV EN+ +STK+CSFG+QV+E++E + +E G +YR PMC+YM FI KL L E +MNSVLENFTILQ VTN T E LLCIAF EVS S+ G+QYH+Y+LI++
Sbjct: 4 DAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHLQVLARRKSREIQSK-------------LKAMNLDQASKD-KALQNMAALSSAQIVSPNLIKSQLPQLPQPPYPPPALAPGSRF----WPTPI---------------PGQPGPSQDIKPFAQTYANLPGPVPPPISAYEPLAPPLAPSATAVP------------------VWQDRTIASSKLRMLEYSAFMEVPR---------DQDSYSKHLFVHIGQTNPSYSDPLLEAVDIRQIYDKFPEKKGGLKELYEKGPQNAFFLVKFWADLNSSDM----QDGPGSFYGVSSQYCSTENMTITVSTKVCSFGKQVVEKVETEYARVEGGKCVYRIHRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTNRETQETLLCIAFVFEVSTSEHGAQYHVYRLIKD 411
BLAST of SD2 vs. Ensembl Cavefish
Match: tead3b (TEA domain transcription factor 3 [Source:NCBI gene;Acc:103042642]) HSP 1 Score: 322.013 bits (824), Expect = 3.196e-104 Identity = 195/472 (41.31%), Postives = 257/472 (54.45%), Query Frame = 1
Query: 130 EAEGVWSPDIENSFNEALQLYPPCGRRKIVLSEEGKMYGRNELIARYIKMQTGKSRSRKQVSSHIQVLARRKSKEIQNQIQEKHTREQARQQLANMSSAQIVSDFKIKENLSLCNDNRNKSPKFVDNNINSFSNTQGI-------SRFSSIHHPTPLVANSKLLDTSSFLLRPNQIPPIMACTNTHNMYLKNDSPNDLISHNHTPI-----PAMWNVPHMXXXXXXXXXXXXXGPHLYVGRSIATPKMRLLELSVFVEAKEYPVKIEKGFGMKNYCKHVFAHLNSTESSLGHPFLEHIEISQIWDKYPET-DGLKEYFERGPQDAFFMVKFWIDMNFDVLPQWNQLSTIIFEGV-------ENVKSKLSTKICSFGRQVLERIEEQSPILENGISIYRFENVPMCDYMRKFIIKLSSLKEHSLMNSVLENFTILQTVTNAFTGEILLCIAFAMEVSISDQGSQYHIYKLIRN 1485
+AEGVWSPDIE SF EAL +YPPCGRRKI+LS+EGKMYGRNELIARYIK++TGK+R+RKQVSSHIQVLAR+K +E QA + N+ A S K +N++ + + SP + + + SRF PTP+ P Q P Y P + P+ P+ VP ++ R+IA+ K+R+LE S F+E +Y KH+F H+ T S P LE ++I QI+DK+PE GLKE +E+GPQ+AFF+VKFW D+N + Q F GV EN+ +STK+CSFG+QV+E++E + +E G +YR PMC+YM FI KL L E +MNSVLENFTILQ VTN T E LLCIAF EVS S+ G+QYH+Y+LI++
Sbjct: 4 DAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARKKVREF-----------QAGIKAMNLDQA---SKDKALQNMAALSSAQIVSPNLIKSQLPQLPQPPYPPPALAPGSRF----WPTPI---------------PGQPGPSQDIKPFAQTYANLPGPVPPPISAYEPLAPPLAPSATAVP------------------VWQDRTIASSKLRMLEYSAFMEVPR---------DQDSYSKHLFVHIGQTNPSYSDPLLEAVDIRQIYDKFPEKKGGLKELYEKGPQNAFFLVKFWADLNSSDM----QDGPGSFYGVSSQYCSTENMTITVSTKVCSFGKQVVEKVETEYARVEGGKCVYRIHRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTNRETQETLLCIAFVFEVSTSEHGAQYHVYRLIKD 411
BLAST of SD2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002687.1 (pep scaffold:Pmarinus_7.0:GL476762:168559:233001:1 gene:ENSPMAG00000002412.1 transcript:ENSPMAT00000002687.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 342.043 bits (876), Expect = 2.360e-112 Identity = 194/481 (40.33%), Postives = 262/481 (54.47%), Query Frame = 1
Query: 130 EAEGVWSPDIENSFNEALQLYPPCGRRKIVLSEEGKMYGRNELIARYIKMQTGKSRSRKQVSSHIQVLARRKSKEIQNQIQ-------------------------EKHTREQARQQLANMSSAQIVSDFKIKEN-LSLCNDNRNKSPKFVDNNINSFSNTQGISRFSSIHHPTPLVANSKLLDTSSFLLRPNQIPPIMACTNTHNMYLKNDSPNDLISHNHTPIPAMWNVPHMXXXXXXXXXXXXXGPHLYVGRSIATPKMRLLELSVFVEAKEYPVKIEKGFGMKNYCKHVFAHLNSTESSLGHPFLEHIEISQIWDKYPET-DGLKEYFERGPQDAFFMVKFWIDMNFDVLPQWNQLSTII--FEGVENVKSKLSTKICSFGRQVLERIEEQSPILENGISIYRFENVPMCDYMRKFIIKLSSLKEHSLMNSVLENFTILQTVTNAFTGEILLCIAFAMEVSISDQGSQYHIYKLIRN 1485
+AEGVWSPDIE SF EAL +YPPCGRRKI+LS+EGKMYGRNELIARYIK++TGK+R+RKQVSSHIQVLAR+K +E Q I+ ++ T+E+A Q +ANMSSAQIVS I + L + P + G S+ D F+ +P + + A + N P GP + GR+I T K+RL+E S F+E P + KH+F H+ + + P LE ++I QI+DK+PE GLKE +++GPQ+AFF+VKFW D+N ++ + + +E EN+ STK+CSFG+QV+E++E + ENG +YR PMC+YM FI KL L E +MNSVLENFTILQ VTN T E LLC+A+ EVS S+ G+Q+HIYKL+++
Sbjct: 15 DAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARKKMREFQTSIKVSSHIQVLARRKSREFQAKLKGMNMDQTTKEKAMQSIANMSSAQIVSATAIHNKVMGLTALPQPSYPTATGFWPGALPGQPGSSQ-----------------DIKPFVQQPYPLQAVAAIPGYESAAGLNPPPG-------------------------------AGP-AWQGRAIGTSKLRLVEFSAFLEQARDP---------DTFNKHLFVHIGQSNPAYSDPLLEAVDIRQIYDKFPEKKGGLKELYDKGPQEAFFLVKFWADLNTNIQEEAGAFYGVTSQYESAENMTITCSTKVCSFGKQVVEKVETEYARFENGRFVYRIHRSPMCEYMINFIHKLKQLPEKYMMNSVLENFTILQVVTNRDTQETLLCVAYVFEVSTSEHGAQHHIYKLVKD 437
BLAST of SD2 vs. Ensembl Yeast
Match: TEC1 (Transcription factor targeting filamentation genes and Ty1 expression; Ste12p activation of most filamentation gene promoters depends on Tec1p and Tec1p transcriptional activity is dependent on its association with Ste12p; binds to TCS elements upstream of filamentation genes, which are regulated by Tec1p/Ste12p/Dig1p complex; competes with Dig2p for binding to Ste12p/Dig1p; positive regulator of chronological life span; TEA/ATTS DNA-binding domain family member [Source:SGD;Acc:S000000287]) HSP 1 Score: 61.6178 bits (148), Expect = 1.895e-10 Identity = 37/91 (40.66%), Postives = 55/91 (60.44%), Query Frame = 1
Query: 145 WSPDIENSFNEALQLYPPCGRRKIVLSEEGKMYGRNELIARYIKMQTGKSRSRKQVSSHIQVLARRKSKEIQNQIQEKHTREQARQQLANM 417
WS +E +F EAL+L G KI + +GRNELI+ YIK +T + R++KQ+SSHIQV K IQN+I++ T ++L ++
Sbjct: 132 WSEKVEEAFLEALRLIMKNGTTKIKIRNAN--FGRNELISLYIKHKTNEFRTKKQISSHIQVW----KKTIQNKIKDSLTLSSKEKELLHL 216
BLAST of SD2 vs. Ensembl Nematostella
Match: EDO36811 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SHJ8]) HSP 1 Score: 232.646 bits (592), Expect = 8.655e-71 Identity = 151/457 (33.04%), Postives = 229/457 (50.11%), Query Frame = 1
Query: 124 SKEAEGVWSPDIENSFNEALQLYPPCGRRKIVLSEEGKMYGRNELIARYIKMQTGKSRSRKQVSSHIQVLARRKSKEIQNQIQEKHTREQARQQLANMSSAQIVSDFKIKENLSLCNDNRNKSPKFVDNNINSFSNTQGISRFSSIHHPTPLVANSKLLDTSSFLLRPNQIPPIMACTNTHNMYLKNDSPNDLISHNHTPIPAMWNVPHMXXXXXXXXXXXXXGPHLYVGRSIATPKMRLLELSVFVEAKEYPVKIEKGFGMKNYCKHVFAHLNSTESSLGHPFLEHIEISQIWDKYPET-DGLKEYFERGPQDAFFMVKFWIDMNFDVLPQWNQLSTI--IFEGVENVKSKLSTKICSFGRQVLERIEEQSPILENGISIYRFENVPMCDYMRKFIIKLSSLKEHSLMNSVLENFTILQTVTNAFTGEILLCIAFAMEVSISDQGSQYHIYKLIRN 1485
+ +AEGVWSPDIE SF EAL +YPPCGRRKI+LS+E GK R ++ I I+ + + + R+Q++ S Q+++ K +E D + + S S+ Q +S +S+ H +K + T+S + N+SP+ + + PA+ P P + + +RL+E S F+E ++ Y KH+F HL ++ P LE ++I QI+DK+PE GLK+ +++GPQ FF+VKFW D+N ++ + + +E EN+ STK+CSFG+QV+E++E + ENG +YR PMC+YM FI KL L E +MNSVLENFTILQ V+N T E LLC+A+ EVS S+ G+Q+HIY+L+++
Sbjct: 2 ANDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDE------------------GKMYGRNEL--------------IARYIKLRTGKTRTRKQVS--SHLQVLARKKAREIQGKIKDQAARDKAL--QTMASMSSAQIVS--ASVLH-------NKSMGTASM---------------SAGYAAANESPSYQRTSAFSGSPALAASP----------------PTGATPWTTSRQPLRLVEFSAFLE--------QQRLDPDTYHKHLFVHLGHN-TNFSDPLLEAVDIRQIYDKFPEKKGGLKDMYDKGPQAVFFLVKFWADLNTNIHDETGAFYGVSSTYESSENMTITCSTKVCSFGKQVVEKVETEYGHFENGRFVYRIHRSPMCEYMINFIHKLKQLPEKYMMNSVLENFTILQVVSNRETQETLLCLAYVFEVSTSEHGAQHHIYRLVKD 373
BLAST of SD2 vs. Ensembl Nematostella
Match: EDO47339 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RMG8]) HSP 1 Score: 125.176 bits (313), Expect = 1.415e-34 Identity = 56/81 (69.14%), Postives = 71/81 (87.65%), Query Frame = 1
Query: 130 EAEGVWSPDIENSFNEALQLYPPCGRRKIVLSEEGKMYGRNELIARYIKMQTGKSRSRKQVSSHIQVLARRKSKEIQNQIQ 372
E EG+W+ DIE SF EAL +YPPCGR+KI+LS + KMYGRNELIARYI M+TGK R+RKQV+SHIQVLAR+K ++IQ++I+
Sbjct: 3 EGEGLWAGDIEQSFQEALAIYPPCGRQKIMLSTKDKMYGRNELIARYILMKTGKMRTRKQVASHIQVLARKKIRQIQSKIK 83
BLAST of SD2 vs. Ensembl Medaka
Match: TEAD1 (TEA domain transcription factor 1 [Source:NCBI gene;Acc:101157846]) HSP 1 Score: 345.51 bits (885), Expect = 2.481e-113 Identity = 204/474 (43.04%), Postives = 272/474 (57.38%), Query Frame = 1
Query: 82 ENICDSNNKNDFDESKEAEGVWSPDIENSFNEALQLYPPCGRRKIVLSEEGKMYGRNELIARYIKMQTGKSRSRKQVSSHIQVLARRKSKEIQNQIQ----EKHTREQARQQLANMSSAQIVSDFKIKENLSLCNDNRNKSPKFVDNNINSFSNTQGISRFSSIHHPTPLVANSKLLDTSSFLLRPNQIPPIMACTNTHNMYLKNDSPNDLISHNHTPIPAMWNVPHMXXXXXXXXXXXXXGPHLYVGRSIATPKMRLLELSVFVEAKEYPVKIEKGFGMKNYCKHVFAHLNSTESSLGHPFLEHIEISQIWDKYPET-DGLKEYFERGPQDAFFMVKFWIDMNFDVLPQWNQLSTII--FEGVENVKSKLSTKICSFGRQVLERIEEQSPILENGISIYRFENVPMCDYMRKFIIKLSSLKEHSLMNSVLENFTILQTVTNAFTGEILLCIAFAMEVSISDQGSQYHIYKLIR 1482
E + DS +K +AEGVWSPDIE SF EAL +YPPCGRRKI+LS+EGKMYGRNELIARYIK++TGK+R+RKQVSSHIQVLARRKS+E ++++ ++ +++A Q +A+MSSAQIVS I L L R P F + QG+ I P + D F +P I P A T T + Y + +P TP W GRSI T K+RL+E S F+E + P +Y KH+F H+ S LE ++I QI+DK+PE GLKE + RGPQ++FF++KFW D+N ++ + + +E EN+ STK+CSFG+QV+E++E + ENG +YR PMC+YM FI KL L E +MNSVLENFTIL VTN T E LLC+A EVS S+ G+Q+HIY+L++
Sbjct: 2 ERMSDSADK---PVDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSREFHSKLKVTSMDQAVKDKALQSMASMSSAQIVSATAIHNKLGLPGIPR---PAFPGAGL-----WQGM-----ISAGQPGSSQ----DIKPFTQQPYPIQP--AVTTTISSYDPSAAP--------TPTAPAWQ-----------------------GRSIGTSKLRLVEFSAFLEQQRDP---------DSYHKHLFVHIGQINHSYSDALLESVDIRQIYDKFPEKKGGLKELYGRGPQNSFFLIKFWADLNCNIQDETGSFYRVTSQYESSENMTITCSTKVCSFGKQVVEKVETEYARFENGRFVYRISRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILLVVTNRDTQETLLCMACVFEVSNSEHGAQHHIYRLVK 413
BLAST of SD2 vs. Ensembl Medaka
Match: TEAD1 (TEA domain transcription factor 1 [Source:NCBI gene;Acc:101157846]) HSP 1 Score: 345.51 bits (885), Expect = 2.947e-113 Identity = 205/474 (43.25%), Postives = 271/474 (57.17%), Query Frame = 1
Query: 82 ENICDSNNKNDFDESKEAEGVWSPDIENSFNEALQLYPPCGRRKIVLSEEGKMYGRNELIARYIKMQTGKSRSRKQVSSHIQVLARRKSKEIQNQIQ----EKHTREQARQQLANMSSAQIVSDFKIKENLSLCNDNRNKSPKFVDNNINSFSNTQGISRFSSIHHPTPLVANSKLLDTSSFLLRPNQIPPIMACTNTHNMYLKNDSPNDLISHNHTPIPAMWNVPHMXXXXXXXXXXXXXGPHLYVGRSIATPKMRLLELSVFVEAKEYPVKIEKGFGMKNYCKHVFAHLNSTESSLGHPFLEHIEISQIWDKYPET-DGLKEYFERGPQDAFFMVKFWIDMNFDVLPQWNQLSTII--FEGVENVKSKLSTKICSFGRQVLERIEEQSPILENGISIYRFENVPMCDYMRKFIIKLSSLKEHSLMNSVLENFTILQTVTNAFTGEILLCIAFAMEVSISDQGSQYHIYKLIR 1482
E + DS +K +AEGVWSPDIE SF EAL +YPPCGRRKI+LS+EGKMYGRNELIARYIK++TGK+R+RKQVSSHIQVLAR+K +EIQ I+ ++ +++A Q +A+MSSAQIVS I L L R P F + QG+ I P + D F +P I P A T T + Y + +P TP W GRSI T K+RL+E S F+E + P +Y KH+F H+ S LE ++I QI+DK+PE GLKE + RGPQ++FF++KFW D+N ++ + + +E EN+ STK+CSFG+QV+E++E + ENG +YR PMC+YM FI KL L E +MNSVLENFTIL VTN T E LLC+A EVS S+ G+Q+HIY+L++
Sbjct: 2 ERMSDSADK---PVDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARKKVREIQAAIKVTSMDQAVKDKALQSMASMSSAQIVSATAIHNKLGLPGIPR---PAFPGAGL-----WQGM-----ISAGQPGSSQ----DIKPFTQQPYPIQP--AVTTTISSYDPSAAP--------TPTAPAWQ-----------------------GRSIGTSKLRLVEFSAFLEQQRDP---------DSYHKHLFVHIGQINHSYSDALLESVDIRQIYDKFPEKKGGLKELYGRGPQNSFFLIKFWADLNCNIQDETGSFYRVTSQYESSENMTITCSTKVCSFGKQVVEKVETEYARFENGRFVYRISRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILLVVTNRDTQETLLCMACVFEVSNSEHGAQHHIYRLVK 413
BLAST of SD2 vs. Ensembl Medaka
Match: TEAD1 (TEA domain transcription factor 1 [Source:NCBI gene;Acc:101157846]) HSP 1 Score: 339.347 bits (869), Expect = 1.211e-110 Identity = 204/491 (41.55%), Postives = 273/491 (55.60%), Query Frame = 1
Query: 82 ENICDSNNKNDFDESKEAEGVWSPDIENSFNEALQLYPPCGRRKIVLSEEGKMYGRNELIARYIKMQTGKSRSRKQVSSHIQVLARRKSKEIQ---------------------NQIQEKHTREQARQQLANMSSAQIVSDFKIKENLSLCNDNRNKSPKFVDNNINSFSNTQGISRFSSIHHPTPLVANSKLLDTSSFLLRPNQIPPIMACTNTHNMYLKNDSPNDLISHNHTPIPAMWNVPHMXXXXXXXXXXXXXGPHLYVGRSIATPKMRLLELSVFVEAKEYPVKIEKGFGMKNYCKHVFAHLNSTESSLGHPFLEHIEISQIWDKYPET-DGLKEYFERGPQDAFFMVKFWIDMNFDVLPQWNQLSTII--FEGVENVKSKLSTKICSFGRQVLERIEEQSPILENGISIYRFENVPMCDYMRKFIIKLSSLKEHSLMNSVLENFTILQTVTNAFTGEILLCIAFAMEVSISDQGSQYHIYKLIR 1482
E + DS +K +AEGVWSPDIE SF EAL +YPPCGRRKI+LS+EGKMYGRNELIARYIK++TGK+R+RKQVSSHIQVLAR+K +EIQ ++++++ +++A Q +A+MSSAQIVS I L L R P F + QG+ I P + D F +P I P A T T + Y + +P TP W GRSI T K+RL+E S F+E + P +Y KH+F H+ S LE ++I QI+DK+PE GLKE + RGPQ++FF++KFW D+N ++ + + +E EN+ STK+CSFG+QV+E++E + ENG +YR PMC+YM FI KL L E +MNSVLENFTIL VTN T E LLC+A EVS S+ G+Q+HIY+L++
Sbjct: 2 ERMSDSADK---PVDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARKKVREIQAAIKVSSHIQVLARRKSREFHSKLKDQAVKDKALQSMASMSSAQIVSATAIHNKLGLPGIPR---PAFPGAGL-----WQGM-----ISAGQPGSSQ----DIKPFTQQPYPIQP--AVTTTISSYDPSAAP--------TPTAPAWQ-----------------------GRSIGTSKLRLVEFSAFLEQQRDP---------DSYHKHLFVHIGQINHSYSDALLESVDIRQIYDKFPEKKGGLKELYGRGPQNSFFLIKFWADLNCNIQDETGSFYRVTSQYESSENMTITCSTKVCSFGKQVVEKVETEYARFENGRFVYRISRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILLVVTNRDTQETLLCMACVFEVSNSEHGAQHHIYRLVK 430
BLAST of SD2 vs. Ensembl Medaka
Match: TEAD1 (TEA domain transcription factor 1 [Source:NCBI gene;Acc:101157846]) HSP 1 Score: 337.806 bits (865), Expect = 5.500e-110 Identity = 205/495 (41.41%), Postives = 271/495 (54.75%), Query Frame = 1
Query: 82 ENICDSNNKNDFDESKEAEGVWSPDIENSFNEALQLYPPCGRRKIVLSEEGKMYGRNELIARYIKMQTGKSRSRKQVSSHIQVLARRKSKEIQNQIQ-------------------------EKHTREQARQQLANMSSAQIVSDFKIKENLSLCNDNRNKSPKFVDNNINSFSNTQGISRFSSIHHPTPLVANSKLLDTSSFLLRPNQIPPIMACTNTHNMYLKNDSPNDLISHNHTPIPAMWNVPHMXXXXXXXXXXXXXGPHLYVGRSIATPKMRLLELSVFVEAKEYPVKIEKGFGMKNYCKHVFAHLNSTESSLGHPFLEHIEISQIWDKYPET-DGLKEYFERGPQDAFFMVKFWIDMNFDVLPQWNQLSTII--FEGVENVKSKLSTKICSFGRQVLERIEEQSPILENGISIYRFENVPMCDYMRKFIIKLSSLKEHSLMNSVLENFTILQTVTNAFTGEILLCIAFAMEVSISDQGSQYHIYKLIR 1482
E + DS +K +AEGVWSPDIE SF EAL +YPPCGRRKI+LS+EGKMYGRNELIARYIK++TGK+R+RKQVSSHIQVLAR+K +EIQ I+ ++ +++A Q +A+MSSAQIVS I L L R P F + QG+ I P + D F +P I P A T T + Y + +P TP W GRSI T K+RL+E S F+E + P +Y KH+F H+ S LE ++I QI+DK+PE GLKE + RGPQ++FF++KFW D+N ++ + + +E EN+ STK+CSFG+QV+E++E + ENG +YR PMC+YM FI KL L E +MNSVLENFTIL VTN T E LLC+A EVS S+ G+Q+HIY+L++
Sbjct: 2 ERMSDSADK---PVDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARKKVREIQAAIKVSSHIQVLARRKSREFHSKLKVTSMDQAVKDKALQSMASMSSAQIVSATAIHNKLGLPGIPR---PAFPGAGL-----WQGM-----ISAGQPGSSQ----DIKPFTQQPYPIQP--AVTTTISSYDPSAAP--------TPTAPAWQ-----------------------GRSIGTSKLRLVEFSAFLEQQRDP---------DSYHKHLFVHIGQINHSYSDALLESVDIRQIYDKFPEKKGGLKELYGRGPQNSFFLIKFWADLNCNIQDETGSFYRVTSQYESSENMTITCSTKVCSFGKQVVEKVETEYARFENGRFVYRISRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILLVVTNRDTQETLLCMACVFEVSNSEHGAQHHIYRLVK 434
BLAST of SD2 vs. Ensembl Medaka
Match: tead3b (TEA domain transcription factor 3 [Source:NCBI gene;Acc:101169194]) HSP 1 Score: 332.028 bits (850), Expect = 1.332e-107 Identity = 199/479 (41.54%), Postives = 270/479 (56.37%), Query Frame = 1
Query: 130 EAEGVWSPDIENSFNEALQLYPPCGRRKIVLSEEGKMYGRNELIARYIKMQTGKSRSRKQVSSHIQVLARRKSKEIQNQIQ-EKHTREQARQQLANMSSAQIVSDFKIKENLSLCNDNRNKSPKFVDNNINSFSNTQGISRFSSIHHPTPLVANSKLLDTSSFLLRPNQIPPIMACTNTHNMYLKNDSPNDLISHNHTPIPAMWNVPHMXXXXXXXXXXXXXGP----------------------HLYVGRSIATPKMRLLELSVFVEAKEYPVKIEKGFGMKNYCKHVFAHLNSTESSLGHPFLEHIEISQIWDKYPET-DGLKEYFERGPQDAFFMVKFWIDMNFDVLPQWNQLSTII---FEGVENVKSKLSTKICSFGRQVLERIEEQSPILENGISIYRFENVPMCDYMRKFIIKLSSLKEHSLMNSVLENFTILQTVTNAFTGEILLCIAFAMEVSISDQGSQYHIYKLIRN 1485
+AEGVWSPDIE SF EAL +YPPCGRRKI+LS+EGKMYGRNELIARYIK++TGK+R+RKQVSSHIQVLAR+K +E Q I+ H Q LA S +I S K ++L +++K+ + N+ + S+ Q +S +H P+ + F P + P S ++ N P H+ + SL GP ++ R+IA+ K+R+LE S F+E + P NY KH+F H+ T S P LE ++I QI+DK+PE GLKE +E+GPQ+AFF+VKFW D+N +P + + EN+ +STK+CSFG+QV+E++E + LE G +YR PMC+YM FI KL L E +MNSVLENFTILQ VTN T E LLCIAF EVS S+ G+QYH+Y+L+++
Sbjct: 4 DAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARKKVREYQAGIKVSSHL-----QVLARRKSREIQSKLKA---MNLDQASKDKALQ----NMAALSSAQIVSPSMIKNHLPPM--SPAPYQPPRFWPGPISVQP-------------GPSQEMVVDLNPGRTPGFSRTSHVIKPFVQPPYQSLQGPVQPAIPAYEPLAPPPAPTATAVPVWQDRTIASSKLRMLEYSAFMEVQRDP---------DNYSKHLFVHIGQTNPSYSDPLLEAVDIRQIYDKFPEKKGGLKELYEKGPQNAFFLVKFWADLNSSGMPDGPGSFYGVSSQYSSAENMTITVSTKVCSFGKQVVEKVETEYARLEGGKCVYRIHRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTNRDTQETLLCIAFVFEVSNSEHGAQYHVYRLVKD 446
BLAST of SD2 vs. Planmine SMEST
Match: SMESG000021468.1 (SMESG000021468.1) HSP 1 Score: 988.408 bits (2554), Expect = 0.000e+0 Identity = 494/518 (95.37%), Postives = 495/518 (95.56%), Query Frame = 1
Query: 52 MECSTTCSSNENICDSNNKNDFDESKEAEGVWSPDIENSFNEALQLYPPCGRRKIVLSEEGKMYGRNELIARYIKMQTGKSRSRKQVSSHIQVLARRKSKEIQNQIQEKHTREQARQQLANMSSAQIVSDFKIKENLSLCNDNRNKSPKFVDNNINSFSNTQGISRFSSIHHPTPLVANSKLLDTSSFLLRPNQIPPIMACTNTHNMYLKNDSPNDLISHNHTPIPAMWNVPHMXXXXXXXXXXXXXGPHLYVGRSIATPKMRLLELSVFVEAKEYPVKIEKGFGMKNYCKHVFAHLNSTESSLGHPFLEHIEISQIWDKYPETDGLKEYFERGPQDAFFMVKFWIDMNFDVLPQWNQLSTIIFEGVENVKSKLSTKICSFGRQVLERIEEQSPILENGISIYRFENVPMCDYMRKFIIKLSSLKEHSLMNSVLENFTILQTVTNAFTGEILLCIAFAMEVSISDQGSQYHIYKLIRNSNLPTLSNFSN*SIIFYQRFFYLLISLIPECKIDSNLCFW 1605
MECSTTCSSNENICDSNNKNDFDESKEAEGVWSPDIENSFNEALQLYPPCGRRKIVLSEEGKMYGRNELIARYIKMQTGKSRSRKQVSSHIQVLARRKSKEIQNQIQEKHTREQARQQLANMSSAQIVSDFKIKENLSLCNDNRNKSPKFVDNNINSFSNTQGISRFSSIHHPTPLVANSKLLDTSSFLLRPNQIPPIMACTNTHNMYLKNDSPNDLISHNHTPIPAMWNVPHMSRASSLSDQSSLLGPHLYVGRSIATPKMRLLELSVFVEAKEYPVKIEKGFGMKNYCKHVFAHLNSTESSLGHPFLEHIEISQIWDKYPETDGLKEYFERGPQDAFFMVKFWIDMNFDVLPQWNQLSTIIFEGVENVKSKLSTKICSFGRQVLERIEEQSPILENGISIYRFENVPMCDYMRKFIIKLSSLKEHSLMNSVLENFTILQTVTNAFTGEILLCIAFAMEVSISDQGSQYHIYKLIRNSNLPTL +CKIDSNLCFW
Sbjct: 1 MECSTTCSSNENICDSNNKNDFDESKEAEGVWSPDIENSFNEALQLYPPCGRRKIVLSEEGKMYGRNELIARYIKMQTGKSRSRKQVSSHIQVLARRKSKEIQNQIQEKHTREQARQQLANMSSAQIVSDFKIKENLSLCNDNRNKSPKFVDNNINSFSNTQGISRFSSIHHPTPLVANSKLLDTSSFLLRPNQIPPIMACTNTHNMYLKNDSPNDLISHNHTPIPAMWNVPHMSRASSLSDQSSLLGPHLYVGRSIATPKMRLLELSVFVEAKEYPVKIEKGFGMKNYCKHVFAHLNSTESSLGHPFLEHIEISQIWDKYPETDGLKEYFERGPQDAFFMVKFWIDMNFDVLPQWNQLSTIIFEGVENVKSKLSTKICSFGRQVLERIEEQSPILENGISIYRFENVPMCDYMRKFIIKLSSLKEHSLMNSVLENFTILQTVTNAFTGEILLCIAFAMEVSISDQGSQYHIYKLIRNSNLPTL-----------------------KCKIDSNLCFW 495
BLAST of SD2 vs. Planmine SMEST
Match: SMESG000077205.1 (SMESG000077205.1) HSP 1 Score: 140.584 bits (353), Expect = 6.413e-36 Identity = 69/96 (71.88%), Postives = 82/96 (85.42%), Query Frame = 1
Query: 73 SSNENICD-SNNKNDFDESK-EAEGVWSPDIENSFNEALQLYPPCGRRKIVLSEEGKMYGRNELIARYIKMQTGKSRSRKQVSSHIQVLARRKSKE 354
+SN +I D +N +D DE K E +GVWS DIE SF EAL +YPPCGRRKI+LS+EGKMYGRNELIARYIK++TGK+R+RKQVSSHIQVLARR+ KE
Sbjct: 20 NSNSDIEDFGDNFDDTDEDKAEEDGVWSADIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRRHKE 115 HSP 2 Score: 129.028 bits (323), Expect = 6.469e-32 Identity = 74/197 (37.56%), Postives = 105/197 (53.30%), Query Frame = 1
Query: 925 HVFAHLNSTESS------LGHPFLEHIEISQIWDKYPETDGLKEYFERGPQDAFFMVKFWIDMNFDVLPQWNQLSTIIFEGVENVKSKLSTKICSFGRQVLERIEEQSPILENGISIYRFENVPMCDYMRKFIIKLSSLKEHSLMNSVLENFTILQTVTNAFTGEILLCIAFAMEVSISDQGS----QYHIYKLIRN 1485
H F HL +S +G FLE I SQIWDK+P GLKE FF++K WIDM ++ +I F+ K L+TKIC+F + ++E + N + EN PMCDY++K +++L K+ MNSVLENF++ QTV A T EILLC+ + V+ D G+ QY +Y ++ N
Sbjct: 255 HEFIHLGPLSNSSVMLENIGPTFLEPINASQIWDKFPLQSGLKELIGTYKNPCFFLLKIWIDMYSELREDDKYRISIKFKTSCPGKICLNTKICTFTKAIVEDKQIIDHSTANDEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRLYSIVNN 451 The following BLAST results are available for this feature:
BLAST of SD2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of SD2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of SD2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of SD2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of SD2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of SD2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of SD2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of SD2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of SD2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of SD2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 1
BLAST of SD2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 1
BLAST of SD2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 2
BLAST of SD2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of SD2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 2
Analyses
This transcript is derived from or has results from the following analyses Cross References
External references for this transcript
Sequences
The following sequences are available for this feature:
transcript sequence >SMED30019046 ID=SMED30019046|Name=SD2|organism=Schmidtea mediterranea sexual|type=transcript|length=1829bpback to top protein sequence of SMED30019046-orf-1 >SMED30019046-orf-1 ID=SMED30019046-orf-1|Name=SMED30019046-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=490bp MECSTTCSSNENICDSNNKNDFDESKEAEGVWSPDIENSFNEALQLYPPCback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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