MFS domain-containing protein
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30019025 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 6
Homology
BLAST of MFS domain-containing protein vs. Ensembl Fly
Match: Sugb (gene:FBgn0036191 transcript:FBtr0273362) HSP 1 Score: 68.5514 bits (166), Expect = 1.329e-11 Identity = 67/265 (25.28%), Postives = 116/265 (43.77%), Query Frame = 3 Query: 783 SAIHSLTDSVTFVTLEKDESHKFGITRVFGSLGILAFSLITALSLYLFDIANKKSSLSLIANMMKLSQ----YSPCFILCGLVFIGVIITSFFLKNDVPKHSDSSWKSFMYIFRNFELSSFLLFAVAGGFVTSVLIEYYFLIILHMFHDLPKYFPGLVFSIFTISEMI-----FMGASPF------LLNYLSNELWISISFLVWAIKWLSYLFVTNYWLLIIIELLNGPAFGLMLPCMMSYISKFAEKSTQGRMQSIFSSLFFNV 1532 + + S+ D++ F L D H +G R+ GSLG F+L+ L + + M L + Y+ F + L+ + S L++ S + K +F + F L+ VA G T+++ + F+ + +L K F G SI T+ ++ F G PF +L + + +S+ + ++++ Y + N W ++ IEL+NG FGL M SY S A T MQS+ ++F V Sbjct: 269 AVVVSIGDAICFGIL-GDRHHLYGKQRLCGSLGWGVFALLAGL----------------LVDHMSLGEVNKNYTAVFWMALLIMGFDVFASSKLRHTPTHLSSNILKDVGQMFLSVRCVIFFLWCVAIGLGTALIWNFLFIYL----EELDKAFEGCDSSIKTLEGLVMGIQCFGGELPFFFLSGWILKKIGHVNAMSVVLFGFGVRFILYSMLQNPWYILPIELMNGVTFGLFYATMASYASIVAPPGTDATMQSLVGAIFEGV 512
BLAST of MFS domain-containing protein vs. Ensembl Fly
Match: Sugb (gene:FBgn0036191 transcript:FBtr0344966) HSP 1 Score: 68.1662 bits (165), Expect = 1.778e-11 Identity = 67/265 (25.28%), Postives = 116/265 (43.77%), Query Frame = 3 Query: 783 SAIHSLTDSVTFVTLEKDESHKFGITRVFGSLGILAFSLITALSLYLFDIANKKSSLSLIANMMKLSQ----YSPCFILCGLVFIGVIITSFFLKNDVPKHSDSSWKSFMYIFRNFELSSFLLFAVAGGFVTSVLIEYYFLIILHMFHDLPKYFPGLVFSIFTISEMI-----FMGASPF------LLNYLSNELWISISFLVWAIKWLSYLFVTNYWLLIIIELLNGPAFGLMLPCMMSYISKFAEKSTQGRMQSIFSSLFFNV 1532 + + S+ D++ F L D H +G R+ GSLG F+L+ L + + M L + Y+ F + L+ + S L++ S + K +F + F L+ VA G T+++ + F+ + +L K F G SI T+ ++ F G PF +L + + +S+ + ++++ Y + N W ++ IEL+NG FGL M SY S A T MQS+ ++F V Sbjct: 269 AVVVSIGDAICFGIL-GDRHHLYGKQRLCGSLGWGVFALLAGL----------------LVDHMSLGEVNKNYTAVFWMALLIMGFDVFASSKLRHTPTHLSSNILKDVGQMFLSVRCVIFFLWCVAIGLGTALIWNFLFIYL----EELDKAFEGCDSSIKTLEGLVMGIQCFGGELPFFFLSGWILKKIGHVNAMSVVLFGFGVRFILYSMLQNPWYILPIELMNGVTFGLFYATMASYASIVAPPGTDATMQSLVGAIFEGV 512
BLAST of MFS domain-containing protein vs. Ensembl Fly
Match: Sugb (gene:FBgn0036191 transcript:FBtr0300100) HSP 1 Score: 68.1662 bits (165), Expect = 1.933e-11 Identity = 67/265 (25.28%), Postives = 116/265 (43.77%), Query Frame = 3 Query: 783 SAIHSLTDSVTFVTLEKDESHKFGITRVFGSLGILAFSLITALSLYLFDIANKKSSLSLIANMMKLSQ----YSPCFILCGLVFIGVIITSFFLKNDVPKHSDSSWKSFMYIFRNFELSSFLLFAVAGGFVTSVLIEYYFLIILHMFHDLPKYFPGLVFSIFTISEMI-----FMGASPF------LLNYLSNELWISISFLVWAIKWLSYLFVTNYWLLIIIELLNGPAFGLMLPCMMSYISKFAEKSTQGRMQSIFSSLFFNV 1532 + + S+ D++ F L D H +G R+ GSLG F+L+ L + + M L + Y+ F + L+ + S L++ S + K +F + F L+ VA G T+++ + F+ + +L K F G SI T+ ++ F G PF +L + + +S+ + ++++ Y + N W ++ IEL+NG FGL M SY S A T MQS+ ++F V Sbjct: 269 AVVVSIGDAICFGIL-GDRHHLYGKQRLCGSLGWGVFALLAGL----------------LVDHMSLGEVNKNYTAVFWMALLIMGFDVFASSKLRHTPTHLSSNILKDVGQMFLSVRCVIFFLWCVAIGLGTALIWNFLFIYL----EELDKAFEGCDSSIKTLEGLVMGIQCFGGELPFFFLSGWILKKIGHVNAMSVVLFGFGVRFILYSMLQNPWYILPIELMNGVTFGLFYATMASYASIVAPPGTDATMQSLVGAIFEGV 512
BLAST of MFS domain-containing protein vs. Ensembl Fly
Match: CG15706 (gene:FBgn0034093 transcript:FBtr0340024) HSP 1 Score: 56.6102 bits (135), Expect = 6.903e-8 Identity = 60/258 (23.26%), Postives = 114/258 (44.19%), Query Frame = 3 Query: 780 FSAIHSLTDSVTFVTLEKDESHKFGITRVFGSLGILAFSLITALSLYLFDIANKKS-SLSLIANMMKLSQYSPCFILCGLVFIGVIITSFFLKNDVPK--HSDSSWKSFMYIFRNFELSSFLLFAVAGGFVTSVLIEYYFLIILHM------FHDLPKYFPGLVFSIFTIS-EMIFMGASPFLLNYLSNELWISISFLVWAIKWLSYLFVTNYWLLIIIEL-LNGPAFGLMLPCMMSYISKFAEKSTQGRMQSIFSSL 1520 F+ +S++D+ F L +E K+G RV+G++G A +++ + + + KS + +LI I+C + + S K +PK S+S W + R + FL FA G + S +I + F + + H + K GLV + ++ E+ F S ++ L +S+ F +A++ ++ N W L+ +EL G + L C+++Y S A T +Q + + + Sbjct: 219 FNVTNSISDACCFDLLGDEEQEKYGAQRVWGTIGFGATAMLAGIVVNWWTTDAVKSLTPALI-------------IMCVFSLLDLFSVS---KLKLPKLGGSESIWSDVWQLVRKPPILVFLFFATMAGIIDSFIIYFMFWHLEQVAEATGYMHQI-KLIEGLVVAAECLAGEVPFFFYSGKIIKKLGYVHCMSMCFFFYAVRLSLIAWIPNPWYLVGVELFFQGITYALCYTCIVAYASAVAPPGTSATVQGLMAGM 459
BLAST of MFS domain-containing protein vs. Ensembl Fly
Match: CG15706 (gene:FBgn0034093 transcript:FBtr0344080) HSP 1 Score: 56.6102 bits (135), Expect = 6.903e-8 Identity = 60/258 (23.26%), Postives = 114/258 (44.19%), Query Frame = 3 Query: 780 FSAIHSLTDSVTFVTLEKDESHKFGITRVFGSLGILAFSLITALSLYLFDIANKKS-SLSLIANMMKLSQYSPCFILCGLVFIGVIITSFFLKNDVPK--HSDSSWKSFMYIFRNFELSSFLLFAVAGGFVTSVLIEYYFLIILHM------FHDLPKYFPGLVFSIFTIS-EMIFMGASPFLLNYLSNELWISISFLVWAIKWLSYLFVTNYWLLIIIEL-LNGPAFGLMLPCMMSYISKFAEKSTQGRMQSIFSSL 1520 F+ +S++D+ F L +E K+G RV+G++G A +++ + + + KS + +LI I+C + + S K +PK S+S W + R + FL FA G + S +I + F + + H + K GLV + ++ E+ F S ++ L +S+ F +A++ ++ N W L+ +EL G + L C+++Y S A T +Q + + + Sbjct: 219 FNVTNSISDACCFDLLGDEEQEKYGAQRVWGTIGFGATAMLAGIVVNWWTTDAVKSLTPALI-------------IMCVFSLLDLFSVS---KLKLPKLGGSESIWSDVWQLVRKPPILVFLFFATMAGIIDSFIIYFMFWHLEQVAEATGYMHQI-KLIEGLVVAAECLAGEVPFFFYSGKIIKKLGYVHCMSMCFFFYAVRLSLIAWIPNPWYLVGVELFFQGITYALCYTCIVAYASAVAPPGTSATVQGLMAGM 459
BLAST of MFS domain-containing protein vs. TrEMBL
Match: A0A267FST2 (MFS domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig032673g3 PE=4 SV=1) HSP 1 Score: 104.76 bits (260), Expect = 1.247e-19 Identity = 109/463 (23.54%), Postives = 208/463 (44.92%), Query Frame = 3 Query: 180 LFMYLTPFMYEFGVTASELAVINFLSHISSFLSRPILGFLADKFQRYREXXXXXXXLCVLLNEFQIAIPK--NYNTHNNTFPHGYFLINDLITNNKLTMCIANKTVVSC----WPSILTNCSRNSTPVEISPLSLFPANITCSSFQ----VYQSRQSNDASVIISLCSQIYKFCTESQVLSITQKFNDSGXXXXXXXXXXXXXXXXXHGLFSAIHSLTDSVTFVTLEKDESHKFGITRVFGSLGILAFSLITALSLYLFDIANKKSSLSLIANMMKLSQYSPCFILCGLVFIGVIITSFFLKNDVPKHSDSSWKSFMYIFRNFELSSFLLFAVAGGFVTSVLIEYYFLIILHMFHDLPKYFPGLVFSIFTISEMIFMGASPFLLNYLSNELWISISFLVWAIKWLSYLFVTNYWLLIIIELLNGPAFGLMLPCMMSYISKFAEKSTQGRMQSIFSSLFFNVEK 1538 L MYL F+ + G+ EL +I+ + +I FL RP+ G +AD++Q YR +++ +L + + +P+ +N TF ND ++C+A ++ + P L NC ++++ + ++ N S +Y+ N ++ +S S++ C Q+ + + K + L + +S + L D+VTF L S +G TR++GS GI +L+T +LY + +A + Y+ FIL ++ + LK + + K+ + ++ + F + + G + E + ++L D P YF G++F++ + E S +++ + I FL +A+++L V N WLL+ + L+G +FGLM P M+ + +K A + QG +Q + S L+F V + Sbjct: 24 LIMYLNMFLMQRGINEFELGLIDTVGYIVGFLMRPVCGAVADRYQAYRPVLLALMLLSAAGFDGMLLLPQPLQAAAYNETFSIVNASYND---TGYASLCLATDSMTNNSYYQAPISLCNC-KSASKDRLDRGTITRLNFLGSESDKQCILYEPASYNYSAKFVSNNSKL--ICKACQLTNSSSKAKSNWNVNFLLALVLKTIGLAG---YSPLLCLLDAVTFSLLGPKPSD-YGWTRMYGSFGIFITALLTGFALYGYSMAWSFRT-----------DYTASFILATVLLAVAAAVTVTLKVPTSTRTLNPLKALPLMCLSWRIGIFYILVLLSGAAFGIF-ESFLAVMLRTMFDPPLYFFGIMFAVQVLVEAPLFALSGCIVSRIGEPACFVIGFLAFALRFLLTSLVPNCWLLLPVNCLHGLSFGLMFPAMLVFAAKQAPEGWQGTVQGLVSGLYFGVGQ 464
BLAST of MFS domain-containing protein vs. TrEMBL
Match: A0A1I8JJH3 (MFS domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig032673g2 PE=4 SV=1) HSP 1 Score: 103.605 bits (257), Expect = 3.460e-19 Identity = 108/463 (23.33%), Postives = 208/463 (44.92%), Query Frame = 3 Query: 180 LFMYLTPFMYEFGVTASELAVINFLSHISSFLSRPILGFLADKFQRYREXXXXXXXLCVLLNEFQIAIPK--NYNTHNNTFPHGYFLINDLITNNKLTMCIANKTVVSC----WPSILTNCSRNSTPVEISPLSLFPANITCSSFQ----VYQSRQSNDASVIISLCSQIYKFCTESQVLSITQKFNDSGXXXXXXXXXXXXXXXXXHGLFSAIHSLTDSVTFVTLEKDESHKFGITRVFGSLGILAFSLITALSLYLFDIANKKSSLSLIANMMKLSQYSPCFILCGLVFIGVIITSFFLKNDVPKHSDSSWKSFMYIFRNFELSSFLLFAVAGGFVTSVLIEYYFLIILHMFHDLPKYFPGLVFSIFTISEMIFMGASPFLLNYLSNELWISISFLVWAIKWLSYLFVTNYWLLIIIELLNGPAFGLMLPCMMSYISKFAEKSTQGRMQSIFSSLFFNVEK 1538 L MYL F+ + G+ EL +I+ + +I FL RP+ G +AD++Q YR +++ +L + + +P+ +N TF ND ++C+A ++ + P L NC ++++ + ++ N S +Y+ N ++ +S S++ C Q+ + + K + L + +S + L D+VTF L S +G TR++GS GI +L+T +LY + +A + Y+ FIL ++ + LK + + K+ + ++ + F + + G + E + ++L D P YF G++F++ + E S +++ + I FL +A+++L V N WLL+ + L+G +FGLM P M+ + +K + + QG +Q + S L+F V + Sbjct: 24 LIMYLNMFLMQRGINEFELGLIDTVGYIVGFLMRPVCGAVADRYQAYRPVLLALMLLSAAGFDGMLLLPQPLQAAAYNETFSIVNASYND---TGYASLCLATDSMTNNSYYQAPISLCNC-KSASKDRLDRGTITRLNFLGSESDKQCILYEPASYNYSAKFVSNNSKL--ICKACQLTNSSSKAKSNWNVNFLLALVLKTIGLAG---YSPLLCLLDAVTFSLLGPKPSD-YGWTRMYGSFGIFITALLTGFALYGYSMAWSFRT-----------DYTASFILATVLLAVAAAVTVTLKVPTSTRTLNPLKALPLMCLSWRIGIFYILVLLSGAAFGIF-ESFLAVMLRTMFDPPLYFFGIMFAVQVLVEAPLFALSGCIVSRIGEPACFVIGFLAFALRFLLTSLVPNCWLLLPVNCLHGLSFGLMFPAMLVFAAKQSPEGWQGTVQGLVSGLYFGVGQ 464
BLAST of MFS domain-containing protein vs. TrEMBL
Match: A0A4Z2D5B1 (Major facilitator superfamily domain-containing 6-like (Fragment) OS=Schistosoma japonicum OX=6182 GN=EWB00_004423 PE=4 SV=1) HSP 1 Score: 98.5969 bits (244), Expect = 1.275e-17 Identity = 114/474 (24.05%), Postives = 216/474 (45.57%), Query Frame = 3 Query: 171 VSCLFMYLTPFMYEFGVTASELAVINFLSHISSFLSRPILGFLAD--KFQRYREXXXXXXXLCVLLNEFQIAIPKNYNTHNNTFPHGYFLI-------NDLITNNKLTMCIANKTVVSCWPSILTNCSRNSTPV---------EISPLSLFPANITCSSFQ----VYQSRQSNDASVIISLCSQIYKFCTESQVLSITQKFNDSGXXXXXXXXXXXXXXXXXHGLFSAIHSLTDSVTFVTLEKDESHKFGITRVFGSLGILAFSLITALSLYLFDIANKKSS---------LSLIANMMKLSQYSPCFI---LCGLVFIGV-IITSFFLKNDVPKHSDSSW-KSFMYIFRNFELSSFLLFAVAGGFVTSVLIEYYFLIILHMFHDLPKYFPGLVFSIFTISEM-IFMGASPFLLNYLSNELWISISFLVWAIKWLSYLFVTNYWLLIIIELLNGPAFGLMLPCMMSYISKFAEK 1481 +S LF+Y+ P + +G+ + +L + + S+ S ++R G +AD K + Y +++ S+ L ++L I K Y + N +G F++ N+ +N T+ + CWP+IL C N + E + L + +++ + Q +Q + I +CS+I + I + D+ ++ L + AH + I +L DSVTF L +++H +G +R GS G + SL+T +++ + N S L +N + ++ SP +I + + +G+ I S F D K ++ + K+ R+ + L+ A G + S + EY +LI+ ++H +P YF GL+ +I I E+ + S ++ + IS ++ I++L Y + NYW L+I E+ A+G+ P +M+ + EK Sbjct: 1 ISSLFIYMNPILATYGLNSYQLGITSLFSNAFSCIARITFGMIADRTKHRNYVLVVLSSTSLGLMLLFLTIPRHKEYVFNGNINENGGFVMHLTPVLRNESQSNYVETLSNDKLHIQPCWPTILKQCHSNDYSIISNDNYHLKEFNSYKLSNVYVNDNNYSYDTLINQKQQFQISKTIQIICSEIVTLNESNCTPLICEHIRDASWSVVLFVLILRCLINSAH---APISNLLDSVTFSILGSEKAHFYGRSRALGSFGFMIGSLLTGFAVHQYTPTNYNHSKQEEINSNVLYYTSNSLNINPISPNYIPAVIIAAISVGIGTIASGFCNYDYTKSIETHFTKALTTAIRSPIMIQCLMVAFITGLIISFIGEYNYLILTTVYH-VPHYFLGLLTTIAIIVEIPTLLFISGIMVKHFGAITCQVISQIMLTIRFLFYAYSINYWYLLIGEI----AYGISYPILMNALLLQTEK 466
BLAST of MFS domain-containing protein vs. TrEMBL
Match: A0A5K4E8E8 (Uncharacterized protein OS=Schistosoma mansoni OX=6183 PE=4 SV=1) HSP 1 Score: 90.8929 bits (224), Expect = 3.090e-15 Identity = 112/475 (23.58%), Postives = 216/475 (45.47%), Query Frame = 3 Query: 189 YLTPFMYEFGVTASELAVINFLSHISSFLSRPILGFLAD--KFQRYREXXXXXXXLCVLLNEFQIAIPKNYNTHNNTFPHGYFLI-------NDLITNNKLTMCIANKTVVSCWPSILTNCSRNSTPVEISPLSLFPANITC---SSFQVYQSRQSNDASVIIS----LCSQIYKFCTESQVLS-------ITQKFNDSGXXXXXXXXXXXXXXXXXHGLFSAIHSLTDSVTFVTLEKDESHKFGITRVFGSLGILAFSLITALSLYLFDIAN-----KKSSLSLI---ANMMKLSQYSPCFI---LCGLVFIGV-IITSFFLKNDVPKHSDSSW-KSFMYIFRNFELSSFLLFAVAGGFVTSVLIEYYFLIILHMFHDLPKYFPGLVFSIFTISEM-IFMGASPFLLNYLSNELWISISFLVWAIKWLSYLFVTNYWLLIIIELLNGPAFGLMLPCMMSYISKFAEKSTQGRMQ 1502 Y+ P + +G+ + +L + + S+ S ++R + G +AD K + Y + + S+ L ++L I K Y + N +G FL+ ND N T+ + CWP +L C+ N + IS + + S V S D S+ + + I C E + + + + D+ ++ +T + AH + I +L DSVTF L +++H +G +R GS G + SL+T ++Y + N +++L+L+ +N + ++ +P +I + L+ +G+ + S F D ++ + K+ R+ + L+ A G + S + EY +LI+ ++H +P YF GL+ + E+ + S L+ + + IS ++ I ++ Y + TNYW L+I E+ A+G+ P +M+ + EK + +M Sbjct: 31 YMNPILATYGLNSYQLGITSLFSNACSCIARIVFGMIADHTKHRNYVLMALSSTSLGLMLLFLTIPRNKAYVFNGNINENGEFLMHLTPLLKNDSQNNYMETLFNDGLNIPPCWPLVLKQCTSNENSI-ISEKNYYQRAFNSHKLSRVYVGDENHSYDLSIHVQQKFPINKTIQLSCVEIETTNGSNCAPLVCEHIRDASWSVVITVLILRCLVSSAH---APISNLLDSVTFSILGSEKAHFYGKSRALGSFGFMIGSLLTGFAVYQYTSINYHHTINETNLNLLYYSSNSLNINSVNPNYIPPIIIALLSVGIGTVASIFCNYDNSNSVETHFTKALTTAIRSPTMIQCLMVAFMTGLIISFVSEYNYLILTTIYH-VPHYFLGLLTTTAITVEIPTLVFVSGILVKHFGAIVCQVISQILLTICFIFYTYSTNYWYLLIGEI----AYGISYPILMNALLLQTEKVSFEKMN 496
BLAST of MFS domain-containing protein vs. TrEMBL
Match: A0A5J4NIJ3 (MFS_1_like domain-containing protein OS=Paragonimus westermani OX=34504 GN=DEA37_0014931 PE=4 SV=1) HSP 1 Score: 87.8113 bits (216), Expect = 6.208e-15 Identity = 70/261 (26.82%), Postives = 123/261 (47.13%), Query Frame = 3 Query: 795 SLTDSVTFVTLEKDESHKFGITRVFGSLG-----ILAFSLITALSLYLFDIANKKSSLSLIANMMK--LSQYSPCFILCGL-VFIGVIITSFFLKNDVPKHSDSSWKSFMYIFRNFELSSFLLFAVAGGFVTSVLIEYYFLIILHMFHDLPKYFPGLVFSIFTISEMIFMGASPFLLNYLSNELWISISFLVWAIKWLSYLFVTNYWLLIIIELLNGPAFGLML------PCMMSYISKFAEKSTQGRMQSIFSSLFFNVE 1535 +L DS T+ L D++H +G +R FGS G ++A +LI+ S D + +S ++ + S Y+P +L G+ IG II+ K DV + ++ + R+ + + LL A G V ++L EY FLI ++P YF G++ ++ +SE+ S + IS + ++A++ S+ F NYW +I + L GPAF L+ ++K MQ++ +++ F V Sbjct: 8 NLLDSTTYGILGPDKTHFYGRSRAFGSAGYVFGAVVAGALISGFSQIGMDQQHTRSPTFASPDISRSPTSNYTPAIVLGGMFALIGTIISGIPSK-DVKSMNMELKQALLTALRSSTMLTCLLNAFLSGLVYAILFEYQFLIFTQQL-NIPPYFMGILIAMIVVSEIPAFFVSGLFIRRFGETTCISFAHALFALRLFSFAFFHNYWFYLITDCLFGPAFPLLYNAFANQSAQAGCVTKGVASGVVASMQALMNAMLFGVS 266
BLAST of MFS domain-containing protein vs. Ensembl Nematostella
Match: EDO37839 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SEM6]) HSP 1 Score: 61.2326 bits (147), Expect = 9.696e-10 Identity = 55/225 (24.44%), Postives = 106/225 (47.11%), Query Frame = 3 Query: 798 LTDSVTFVTLEKDESHKFGITRVFGSLGILAFSLITALSLYLFDIANKKSSLSLIANMMKLSQYSPCFILCGL-VFIGVIITSFF-LKNDVPKHS-DSSWKSFMYIFRNFELSSFLLFAVAGGFVTSVLIEYYFLIILHMFHDLPKYFPGLVFSIFTISEMIFMGASPFLLNYLSNELWISISFLVWAIKWLSYLFVTNYWLLIIIELLNGPAFGLMLPCMMSYI 1463 LTDS T L E H++G R+FGSLG A +L+ + F +++ Y P F + L +F+ ++T FF K+ K + D S+ + +F N + +SF+ + GF S+ + + F L P F +V + ++SE+ S + + + N+ + + + +++L Y ++ W ++ +E+L G +G + +SY+ Sbjct: 322 LTDSGTLSLLTGKE-HEYGKQRLFGSLGWGAGALVAGFVVTAFHSCQYSDNIN----------YVPVFYVFALAMFLNFVVTLFFRFKSGGEKSAWDKSYTEGLKVFCNVKNASFIFVLLFLGFSHSLQLSFLFW-FLQDIGGTPMLFT-MVMLVNSLSEVFMFLWSTYAVQRIGNDGMLYVGLGCYGVRFLFYSYIEQPWYVLPLEILQGATYGGVWTASVSYV 533
BLAST of MFS domain-containing protein vs. Ensembl Nematostella
Match: EDO46692 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RP85]) HSP 1 Score: 58.5362 bits (140), Expect = 8.410e-9 Identity = 63/247 (25.51%), Postives = 112/247 (45.34%), Query Frame = 3 Query: 798 LTDSVTFVTLEKDESHKFGITRVFGSLGILAFSLITALSLYLFDIANKKSSLSLIANMMKLSQYSPCFILCGLVFIGVIITSFFLKNDVPKHSDSSWKSF--MYIFRNFELSSFLLFAVAGGFVTSVLIEYYFLIILHMFHDLPKYFPGLVFSIFTISEMIFMGASPFLLNYLSNELWISISFLVWAIKWLSYLFVTNYWLLIIIELLNGPAFGLMLPCMMSYISKFAEKSTQGRMQSIFSSLFFNV 1532 L DS L ES ++G R+ GS G+ +L+ AL L+ + +++ Y PCF L + II S F K D P + F + F+ FLL GF S+ I + F L P F ++ +++ +E++ +S F++ + ++ +S++ + ++L Y +T+ WL+I IEL+ G +G + +YIS E S+ +Q+I ++ V Sbjct: 346 LADSEVVQALANTES-RYGDQRLLGSFGLALAALLAALWTTLWSECHYTDTIN----------YLPCFYLFEIALAATIIISLFFKLDSPDIEGNEVNIFDGLKFFKTPRAGFFLLTIFLLGFAHSIQISFLFWF-LQDLGGTPILF-AVIIIVYSFAEVVMYFSSSFVVQKIGHQGTLSLALACYTARFLMYANLTDPWLVIPIELVQGLTYGGVWSIAPTYISVPEEASSM--IQNILQGAYWGV 577
BLAST of MFS domain-containing protein vs. Ensembl Nematostella
Match: EDO37430 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SFX7]) HSP 1 Score: 56.6102 bits (135), Expect = 2.838e-8 Identity = 66/247 (26.72%), Postives = 117/247 (47.37%), Query Frame = 3 Query: 795 SLTDSVTFVTLEKDESHKFGITRVFGSL--GILAFSLITALSLYLFDIANKKSSLSLIANMMKLSQYSPCFILCGLVFIGVIITSF---FLKNDVPKHSDSSWKSFMYIFRNFELSSFLLFAVAG---GFVTSVLIEYYFLIILHMFHDLPKYFPG--LVFSIFT----ISEMIFMGASPFLLNYLSNELWISISFLVWAIKWLSYLFVTNYWLLIIIELLNGPAFGLMLPCMMSYISKFAEKSTQG 1493 SL D+VT L D+ H++G+ R++GSL G+ AF + +S + + + S ++ + Y+PCF +ITSF F + PK S +Y R+ FL+F + GF+ + + F H+ K G L+F I T I+E+ S LL ++++ + + FL +AI+ +Y +T+ W+++ +E+L+G M++++S E ST G Sbjct: 17 SLADTVTMHNLGGDK-HRYGVQRLWGSLGFGVAAFGIGALVSARGYCMGDSGDSQTVDVD------YTPCFYSFAAFLSCALITSFKFNFPNDTCPKGKTSDR---LYTVRSLLRGRFLMFLLVAFHFGFMIAFTKTFLF---WHL-----KELGGTQLLFCIITAVNCIAEVTMYFLSAKLLTFITHTRVLYMGFLCYAIRAFAYYLITSPWMVLTVEILSGITSAASWAAMLAFVS---ENSTPG 242
BLAST of MFS domain-containing protein vs. Ensembl Nematostella
Match: EDO38796 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SBW5]) HSP 1 Score: 50.0618 bits (118), Expect = 2.423e-6 Identity = 50/235 (21.28%), Postives = 101/235 (42.98%), Query Frame = 3 Query: 843 HKFGITRVFGSLGILAFSLITALSLYLFDIANKKSSLSLIANMMKLSQYSPCFILC-----GLVFIGVIITSFFLKNDV-PKHSDSSWKSFMYIFRNFELSSFLLFAVAGGFVTSVLIEYYFLIILHMFHDLPKYFPGLVFSIFTISEMIFMGASPFLLNYLSNELWISISFLVWAIKWLSYLFVTNYWLLIIIELLNGPAFGLMLPCMMSYISKFAEKSTQGRMQSIFSSLFFN 1529 ++G R++G+ G SL+T ++ ++ S ++ I L + P F+ GL +++ F + + K ++ + + E FL+ G V++ + F + + + GLV + +EM+ + ++ L + I ++ I+ L Y F+ N W ++++E +NG F M +SY S A Q MQ + SS+++N Sbjct: 174 ERYGHQRLYGAFGFGIGSLVTGFAM------DQTSHVTYIPG--SLPHHGPNFLTAFIINFGLSVFALLLIGFTFEITINEKKIPPNFAKHIGLLIRKETVLFLIILFITGVANGVIMSFLFWFLRDI--GASQTLLGLVTVVMCSAEMLVFSCTGTMIGRLGHVGVIILALACTIIRLLIYPFLENPWYVLLVEPMNGITFAAMWATCVSYASILAPNEVQSTMQGVVSSVYYN 398
BLAST of MFS domain-containing protein vs. Ensembl Nematostella
Match: EDO42918 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S083]) HSP 1 Score: 48.9062 bits (115), Expect = 8.318e-6 Identity = 52/240 (21.67%), Postives = 107/240 (44.58%), Query Frame = 3 Query: 795 SLTDSVTFVTLEKDESHKFGITRVFGSLGILAFSLITALSL-YLFDIANKKSSLSLIANMMKLSQYSPCF----ILCGLVFIGVIITSFFLKNDVPKHSDSSWKSFMYIFRNFELSSFLLFAVAGGFVTSVLIEYYFLIILHMFHDLPKYFPGLVFSIFTISEMIFMGASPFLLNYLSNELWISISFLVWAIKWLSYLFVTNYWLLIIIELLNGPAFGLMLPCMMSYISKF--AEKSTQG 1493 +L D+ T L D ++G R++GS+G + I +L YL ++ + LS+ Y PCF IL G+ ++I F DV K +++ + N + F+L + G L + F +L + ++ + ++ +SE++ S L+ + + + + +A+++ +Y FVT+ WL + +E L+G ++ + + ++ A + QG Sbjct: 423 TLADTTTLRGL-GDNVEEYGRQRMWGSIGWGMGAFIVGSTLSYLQELNGCNNPLSV--------DYMPCFYAFAILMGVT---ILIGGLFEFEDV-KRDETTLLQGLNNLCNIQYLYFILTMLFCGGAFGCLQTFLFWHLLEI--GGTQFLFSAITAVQCVSEILMFSMSGVLIRCCGYQRVLYLGLICYAVRFFAYAFVTDCWLALPLECLHGVSYAAVWSAAVVFVGLIPGANNTMQG 647
BLAST of MFS domain-containing protein vs. Planmine SMEST
Match: SMESG000030276.1 (SMESG000030276.1) HSP 1 Score: 473.781 bits (1218), Expect = 3.648e-164 Identity = 240/240 (100.00%), Postives = 240/240 (100.00%), Query Frame = 3 Query: 1452 MSYISKFAEKSTQGRMQSIFSSLFFNVEKMQPYKIPKIAKPNTSTEDTLHRQRQVSYKKYAEHELTLGTWFAPEAAKAVQQHIHRINQAFSRPRSGHEIKFXXXXXXXXXXXXXXLQNSTYQKETLPPAKTGDAVNVIWLRDHFSGKCFKRVRRGISPEFVKRDISVHKFHAYINDEMKISLVVKLMVETPQPRQQEVMETQNSSTSVEYWTDDFSDEICHTVPQVGTTKFKFFRYQKLP 2171 MSYISKFAEKSTQGRMQSIFSSLFFNVEKMQPYKIPKIAKPNTSTEDTLHRQRQVSYKKYAEHELTLGTWFAPEAAKAVQQHIHRINQAFSRPRSGHEIKFNSGNSHSGESNHQSLQNSTYQKETLPPAKTGDAVNVIWLRDHFSGKCFKRVRRGISPEFVKRDISVHKFHAYINDEMKISLVVKLMVETPQPRQQEVMETQNSSTSVEYWTDDFSDEICHTVPQVGTTKFKFFRYQKLP Sbjct: 1 MSYISKFAEKSTQGRMQSIFSSLFFNVEKMQPYKIPKIAKPNTSTEDTLHRQRQVSYKKYAEHELTLGTWFAPEAAKAVQQHIHRINQAFSRPRSGHEIKFNSGNSHSGESNHQSLQNSTYQKETLPPAKTGDAVNVIWLRDHFSGKCFKRVRRGISPEFVKRDISVHKFHAYINDEMKISLVVKLMVETPQPRQQEVMETQNSSTSVEYWTDDFSDEICHTVPQVGTTKFKFFRYQKLP 240
BLAST of MFS domain-containing protein vs. Planmine SMEST
Match: SMESG000030270.1 (SMESG000030270.1) HSP 1 Score: 382.104 bits (980), Expect = 5.407e-124 Identity = 225/463 (48.60%), Postives = 314/463 (67.82%), Query Frame = 3 Query: 150 YFFELSAVSCLFMYLTPFMYEFGVTASELAVINFLSHISSFLSRPILGFLADKFQRYREXXXXXXXLCVLLNEFQIAIPKNYNTHNNTFPHGYFLINDLITNNKLTMCIANKTVVSCWPSILTNCSRNSTPVEISPLSLFPANITCSSFQVYQSRQSN--DASVIISLCSQIYKFCTESQVLSITQKFNDSGXXXXXXXXXXXXXXXXXHGLFSAIHSLTDSVTFVTLEKDESHKFGITRVFGSLGILAFSLITALSLYLFDIANKKSSLSLIANMMKLSQYSPCFILCGLVFIGVIITSFFLKNDVPKHSDSSWKSFMYIFRNFELSSFLLFAVAGGFVTSVLIEYYFLIILHMFHDLPKYFPGLVFSIFTISEMIFMGASPFLLNYLSNELWISISFLVWAIKWLSYLFVTNYWLLIIIELLNGPAFGLMLPCMMSYISKFAEKSTQGRMQSIFSSLFFNV 1532 YFFELS V+CLF+YL PFM E GV+ SELAVINF++HI +F +RP G++ADK QRYREI+ +S+ LC ++N Q+ IPK Y N YFL+ + N+ T+C +N + + C P N +S ++IS + +P NI CS ++Q +N +AS + C+ + C + + S+ + +SG T SLTF+LF I K H +SA SLTD+VTFVTL KD+ HKFG+TR+FG+LGIL FSL TA+ L LF ++ + S I+ + +S Y+PCFIL +F V++ S L ND P HS+ W S +FRN E+S F +F++ GGF+ S LIEYYF++I MF +PKYFPGL+F++ TI+E IF GAS +L + ++E WIS +F WA++WLSY +TNYW ++IE LNGPAFGL+LPCMM++ISKFA +STQGR+Q +F+ LFFN+ Sbjct: 16 YFFELSVVACLFIYLNPFMVERGVSGSELAVINFVAHIVAFFTRPFFGYMADKHQRYREILAVSAALCFIINLVQLFIPK-YQKSN-----PYFLLANFEENDNFTVCFSNSSNILCQP---CNNGSSSQVLDIS-IYRYPINIQCSGIPIFQLNSTNHFNAS---NFCNNLSTPCFD-YLKSLNKSETNSGLTCSLTFWLFLICKILGHTFYSANISLTDAVTFVTLGKDKCHKFGVTRMFGTLGILVFSLTTAVMLQLFF---QQPNYSWISYLKSVSSYTPCFILGLAMFAFVVLFSLLLGNDKPLHSEPFWTSLGLLFRNLEISIFFIFSIFGGFIFSTLIEYYFIVIFQMFPQMPKYFPGLIFAVMTIAEAIFNGASSIILKFANDEFWISFAFFTWALRWLSYYLITNYWFFLMIEFLNGPAFGLLLPCMMAHISKFANRSTQGRVQCVFAGLFFNI 461
BLAST of MFS domain-containing protein vs. Planmine SMEST
Match: SMESG000030274.1 (SMESG000030274.1) HSP 1 Score: 348.591 bits (893), Expect = 3.423e-116 Identity = 176/178 (98.88%), Postives = 176/178 (98.88%), Query Frame = 3 Query: 186 MYLTPFMYEFGVTASELAVINFLSHISSFLSRPILGFLADKFQRYREXXXXXXXLCVLLNEFQIAIPKNYNTHNNTFPHGYFLINDLITNNKLTMCIANKTVVSCWPSILTNCSRNSTPVEISPLSLFPANITCSSFQVYQSRQSNDASVIISLCSQIYKFCTESQVLSITQKFNDSG 719 MYLTPFMYEFGVTASELAVINFLSHISSFLSRPILGFLADKFQRYREIIIISSILCVLLNEFQIAIPKNYNTHNNTFPHGYFLINDLITNNKLTMCIANKTVVSCWPSILTNCSRNSTPVEISPLSLFP NITCSSFQVYQSRQSNDASVIISLCSQIYKFCTESQVLSITQKFNDS Sbjct: 1 MYLTPFMYEFGVTASELAVINFLSHISSFLSRPILGFLADKFQRYREIIIISSILCVLLNEFQIAIPKNYNTHNNTFPHGYFLINDLITNNKLTMCIANKTVVSCWPSILTNCSRNSTPVEISPLSLFPTNITCSSFQVYQSRQSNDASVIISLCSQIYKFCTESQVLSITQKFNDSA 178
BLAST of MFS domain-containing protein vs. Planmine SMEST
Match: SMESG000030274.1 (SMESG000030274.1) HSP 1 Score: 335.495 bits (859), Expect = 2.687e-111 Identity = 170/172 (98.84%), Postives = 170/172 (98.84%), Query Frame = 3 Query: 204 MYEFGVTASELAVINFLSHISSFLSRPILGFLADKFQRYREXXXXXXXLCVLLNEFQIAIPKNYNTHNNTFPHGYFLINDLITNNKLTMCIANKTVVSCWPSILTNCSRNSTPVEISPLSLFPANITCSSFQVYQSRQSNDASVIISLCSQIYKFCTESQVLSITQKFNDSG 719 MYEFGVTASELAVINFLSHISSFLSRPILGFLADKFQRYREIIIISSILCVLLNEFQIAIPKNYNTHNNTFPHGYFLINDLITNNKLTMCIANKTVVSCWPSILTNCSRNSTPVEISPLSLFP NITCSSFQVYQSRQSNDASVIISLCSQIYKFCTESQVLSITQKFNDS Sbjct: 1 MYEFGVTASELAVINFLSHISSFLSRPILGFLADKFQRYREIIIISSILCVLLNEFQIAIPKNYNTHNNTFPHGYFLINDLITNNKLTMCIANKTVVSCWPSILTNCSRNSTPVEISPLSLFPTNITCSSFQVYQSRQSNDASVIISLCSQIYKFCTESQVLSITQKFNDSA 172
BLAST of MFS domain-containing protein vs. Planmine SMEST
Match: SMESG000008715.1 (SMESG000008715.1) HSP 1 Score: 260.381 bits (664), Expect = 2.162e-77 Identity = 180/482 (37.34%), Postives = 281/482 (58.30%), Query Frame = 3 Query: 150 YFFELSAVSCLFMYLTPFMYEFGVTASELAVINFLSHISSFLSRPILGFLADKFQRYREXXXXXXXLCVLLNEFQIAIPKNY-NTHNNTFPHGYFLINDLITNNKLTMCIANKTVVSCWPSILTNCSRNSTPVEISPLSL--FPANITCSSFQVYQSRQSNDASVIIS---LCSQIYKFC---TESQVLSITQKFNDSGXXXXXXXXXXXXXXXXXHGLFSAIHSLTDSVTFVTLEKDESHKFGITRVFGSLGILAFSLITALSLYLFDIANKKSSLSLIANMMKLSQYSPCFILCGLVFIGVIITSFFLKND--VPKHSDSSWKSFMYIFRN--------FE--LSSFLLFAVAGGFVTSVLIEYYFLIILHMFHDLPKYFPGLVFSIFTISEMIFMGASPFLLNYLSNELWISISFLVWAIKWLSYLFVTNYWLLIIIELLNGPAFGLMLPCMMSYISKFAEKSTQGRMQSIFSSLFFNV 1532 YFFELS S + +YL+PFM ++GVT SELAVINF HI +F SRP+ GF+ADK+Q ++++II +I + +A+P++ N + F++ND + +C +N + V CWPS ++NC T +S ++L + N TC+ ++ + QSN I+S C + + C T+S V + + T+S TF++ I + + S + +LTDS+ F+ L S+++G TR+FG++G+ S +T LYL DI K SSL IAN+ SQ+S CF+L LV++ +I+ F+ +D V + S KS + F + F+ L+ F LF V GFV +V EY+ +I+ F+ +PK+ PGL+ I T+SE + G S +L+ E W+S SFLVW +WL+Y F+ +W +I E+++G FGL + M+SYI K + STQGR+Q +FSSL+FN+ Sbjct: 16 YFFELSVYSVIIIYLSPFMVKWGVTMSELAVINFAVHIVTFFSRPLFGFIADKYQNFKQLIIFIAITSSISFFLFLAVPRHVPKVLNYSLEKNLFMVNDS-RIGFMGICASNISGV-CWPSNMSNC----TFCGLSKINLTRYYYNETCAFYRFDSANQSNYNKAILSDSMKCLNVDQNCGNHTKSHVF--FEIYKKISLTWSSTFWMLGILRIIGFAVCSPLSNLTDSLIFIVLGPKRSNEYGHTRMFGTVGVFVLSFVTGGLLYLMDILTKYSSL--IANIQSYSQFSLCFLLEVLVYVTIIVIVSFVTHDKVVQEKRKSRNKSCIRKFMDKTSLNMVCFDSNLAIFFLFTVLAGFVETVHCEYFMVILFQKFNYVPKFLPGLLVGIMTLSESLVFGISRKMLDLCRYEFWVSFSFLVWFFRWLTYTFIKYFWQFLITEIIHGFTFGLQIASMVSYIGKRTDPSTQGRVQGLFSSLYFNI 487 The following BLAST results are available for this feature:
BLAST of MFS domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 0
BLAST of MFS domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 0
BLAST of MFS domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of MFS domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 0
BLAST of MFS domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 0
BLAST of MFS domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 0
BLAST of MFS domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 0
BLAST of MFS domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of MFS domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 0
BLAST of MFS domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 0
BLAST of MFS domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of MFS domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of MFS domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 0
BLAST of MFS domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30019025 ID=SMED30019025|Name=MFS domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=2284bpback to top protein sequence of SMED30019025-orf-1 >SMED30019025-orf-1 ID=SMED30019025-orf-1|Name=SMED30019025-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=690bp MPFKINKKLLIIKILYFFELSAVSCLFMYLTPFMYEFGVTASELAVINFLback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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