ATP-dependent DNA helicase

Overview


Name	ATP-dependent DNA helicase
Smed ID	SMED30018991
Length (bp)	2149

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of ATP-dependent DNA helicase (SMED30018991) t-SNE clustered cells

Violin plots show distribution of expression levels for ATP-dependent DNA helicase (SMED30018991) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of ATP-dependent DNA helicase (SMED30018991) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for ATP-dependent DNA helicase (SMED30018991) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30018991

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 9

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
nervous system	SMED30018991	SMESG000064966.1	dd_Smed_v4_7318_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neuron	SMED30018991	SMESG000064966.1	dd_Smed_v4_7318_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parapharyngeal region	SMED30018991	SMESG000064966.1	dd_Smed_v4_7318_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30018991	SMESG000064966.1	dd_Smed_v4_7318_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30018991	SMESG000064966.1	Contig29612	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30018991	SMESG000064966.1	Contig29612	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30018991	SMESG000064966.1	Contig50813	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30018991	SMESG000064966.1	Contig50813	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Category 2 cell	SMED30018991	SMESG000064966.1	dd_Smed_v4_7318_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of ATP-dependent DNA helicase vs. Ensembl Human
Match: RECQL (RecQ like helicase [Source:HGNC Symbol;Acc:HGNC:9948])

HSP 1 Score: 408.683 bits (1049), Expect = 4.787e-133
Identity = 246/609 (40.39%), Postives = 353/609 (57.96%), Query Frame = 1

Query:  112 IDKRIVAIDNEIKTLTHEKEDLIKKKKQ--------LSISTKGHS---ITSNKDYGKENFPWSSNIKKLLQDKFKIKNFKSLQLKTINATLDKLDCIFISSPGSGKSLCYQLASMIS-GFTLVIAPLGSLIQDQMIVSEKFGISCISLDSNSSVKIQNEIFKAMETDPVD-NVTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRLVIDEIHCCSELSHDFRQDYKNLHGLKSLYPNLPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEVKF-LSNEKKEGEEICKLIKSRFDGQSGIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNENCKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFWKLAEYFKIGSNIFTEKSGIPNLNIMNRYILDDCTCKRVSLSSILDEKFTVNDCKNMCSVCADTESEMSSIDIADVYKSALTIIKNIEKTKNPKITGKKIISELANQMS--LYFAD-LANRFPGIDYKLFLDKAFCHLVLVGYLKLDYSFGSFSNFTYVIAGSKT-LKSNEKIDIPIRIAKSDKMRNLVQNVKQNESSNV 1884
            I   + A++ +I+ LT  +++LI+KKK         L  S  G S    +S   + KE+FPWS  +K +LQ+ FK++ F+ LQL+TIN T+   +   +   G GKSLCYQL ++ S GFTLVI PL SL++DQ++V ++ GIS   L+++SS     E  K +  + V+ N   KLIY TP+KI+ SK     +EKAY  +R  R+ +DE+HCCS+  HDFR DYK L  LK  +PN  ++GLTATA N V+ D +  L +   C     ++NR N++YEV+   SN +   E+I KLI  R+ GQSGI++CF+QKD E +T  L N GI A +Y+  L  + K  +H KW     +V+VAT AFGMGIDKP+VRFVIH SMSKS+ENYYQESGRAGRD  ++DCIL++   + F+I S +  E  G   L  M  Y  +   C+RV ++   DE +    C  MC  C   +S     +I +  +  + I+K  E+  N K+T  K+I     + +  L  A  +A   P  D    L+K   H ++  YLK DYSF +++  +Y+  G K  L +NE   I +++ KS       QN  + ESS  
Sbjct:   14 ITSELHAVEIQIQELTERQQELIQKKKVLTKKIKQCLEDSDAGASNEYDSSPAAWNKEDFPWSGKVKDILQNVFKLEKFRPLQLETINVTMAGKEVFLVMPTGGGKSLCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATMLNASSS----KEHVKWVHAEMVNKNSELKLIYVTPEKIAKSKMFMSRLEKAYEARRFTRIAVDEVHCCSQWGHDFRPDYKALGILKRQFPNASLIGLTATATNHVLTDAQKILCIEK-CFTFTASFNRPNLYYEVRQKPSNTEDFIEDIVKLINGRYKGQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKWSANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKADCILYYGFGDIFRISSMVVMENVGQQKLYEMVSYCQNISKCRRVLMAQHFDEVWNSEACNKMCDNCCK-DSAFERKNITEYCRDLIKILKQAEEL-NEKLTPLKLIDSWMGKGAAKLRVAGVVAPTLPRED----LEKIIAHFLIQQYLKEDYSFTAYATISYLKIGPKANLLNNEAHAITMQVTKS------TQNSFRAESSQT 605

[Close]

Query:  112 IDKRIVAIDNEIKTLTHEKEDLIKKKKQ--------LSISTKGHS---ITSNKDYGKENFPWSSNIKKLLQDKFKIKNFKSLQLKTINATLDKLDCIFISSPGSGKSLCYQLASMIS-GFTLVIAPLGSLIQDQMIVSEKFGISCISLDSNSSVKIQNEIFKAMETDPVD-NVTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRLVIDEIHCCSELSHDFRQDYKNLHGLKSLYPNLPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEVKF-LSNEKKEGEEICKLIKSRFDGQSGIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNENCKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFWKLAEYFKIGSNIFTEKSGIPNLNIMNRYILDDCTCKRVSLSSILDEKFTVNDCKNMCSVCADTESEMSSIDIADVYKSALTIIKNIEKTKNPKITGKKIISELANQMS--LYFAD-LANRFPGIDYKLFLDKAFCHLVLVGYLKLDYSFGSFSNFTYVIAGSKT-LKSNEKIDIPIRIAKSDKMRNLVQNVKQNESSNV 1884
            I   + A++ +I+ LT  +++LI+KKK         L  S  G S    +S   + KE+FPWS  +K +LQ+ FK++ F+ LQL+TIN T+   +   +   G GKSLCYQL ++ S GFTLVI PL SL++DQ++V ++ GIS   L+++SS     E  K +  + V+ N   KLIY TP+KI+ SK     +EKAY  +R  R+ +DE+HCCS+  HDFR DYK L  LK  +PN  ++GLTATA N V+ D +  L +   C     ++NR N++YEV+   SN +   E+I KLI  R+ GQSGI++CF+QKD E +T  L N GI A +Y+  L  + K  +H KW     +V+VAT AFGMGIDKP+VRFVIH SMSKS+ENYYQESGRAGRD  ++DCIL++   + F+I S +  E  G   L  M  Y  +   C+RV ++   DE +    C  MC  C   +S     +I +  +  + I+K  E+  N K+T  K+I     + +  L  A  +A   P  D    L+K   H ++  YLK DYSF +++  +Y+  G K  L +NE   I +++ KS       QN  + ESS  
Sbjct:   14 ITSELHAVEIQIQELTERQQELIQKKKVLTKKIKQCLEDSDAGASNEYDSSPAAWNKEDFPWSGKVKDILQNVFKLEKFRPLQLETINVTMAGKEVFLVMPTGGGKSLCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATMLNASSS----KEHVKWVHAEMVNKNSELKLIYVTPEKIAKSKMFMSRLEKAYEARRFTRIAVDEVHCCSQWGHDFRPDYKALGILKRQFPNASLIGLTATATNHVLTDAQKILCIEK-CFTFTASFNRPNLYYEVRQKPSNTEDFIEDIVKLINGRYKGQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKWSANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKADCILYYGFGDIFRISSMVVMENVGQQKLYEMVSYCQNISKCRRVLMAQHFDEVWNSEACNKMCDNCCK-DSAFERKNITEYCRDLIKILKQAEEL-NEKLTPLKLIDSWMGKGAAKLRVAGVVAPTLPRED----LEKIIAHFLIQQYLKEDYSFTAYATISYLKIGPKANLLNNEAHAITMQVTKS------TQNSFRAESSQT 605

[Close]

BLAST of ATP-dependent DNA helicase vs. Ensembl Human
Match: BLM (BLM RecQ like helicase [Source:HGNC Symbol;Acc:HGNC:1058])

HSP 1 Score: 287.345 bits (734), Expect = 1.366e-82
Identity = 167/449 (37.19%), Postives = 247/449 (55.01%), Query Frame = 1

Query:  253 NFPWSSNIKKLLQDKFKIKNFKSLQLKTINATLDKLDCIFISSPGSGKSLCYQLASMIS-GFTLVIAPLGSLIQDQMIVSEKFGISCISLDSNSSVKIQNEIFKAM-ETDPVDNVTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRLVIDEIHCCSELSHDFRQDYKNLHGLKSLYPNLPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEVKFLSNEKKEGEEICKLIKSRFDGQSGIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNEN-CKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFWKLAEYFKIGSNIFTEKSG--------IPNLNIMNRYILDDCTCKRVSLSSILDEK-FTVNDCKNMCSVCADTESEMSSIDIADVYKSALTIIKNIEK 1563
            +FP +  + K+   KF + NF++ QL+ INA L   DC  +   G GKSLCYQL + +S G T+VI+PL SLI DQ+       I    L  + +      I+  + + DP+     KL+Y TP+KI  S +L   +E  Y  K L R VIDE HC S+  HDFRQDYK ++ L+  +P++PV+ LTATAN  V  DI T L +     V   ++NR N+ Y V      KK   +  + I+      SGI++C ++++C+ + + L  +G+ A +Y+  L    + ++  KW+N++ C+VI AT AFGMGIDKP+VRFVIH S+ KS+E YYQESGRAGRDG+ S C+LF+   +  ++   I  EK G          NL  M  Y  +   C+R+ L +   E  F  + CK    V  D   +       DV     +I++ +++
Sbjct:  648 SFPHTKEMMKIFHKKFGLHNFRTNQLEAINAALLGEDCFILMPTGGGKSLCYQLPACVSPGVTVVISPLRSLIVDQVQKLTSLDIPATYLTGDKTDSEATNIYLQLSKKDPI----IKLLYVTPEKICASNRLISTLENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPSVPVMALTATANPRVQKDILTQLKILRP-QVFSMSFNRHNLKYYV-LPKKPKKVAFDCLEWIRKHHPYDSGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVICATIAFGMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKRLIMMEKDGNHHTRETHFNNLYSMVHYCENITECRRIQLLAYFGENGFNPDFCKKHPDVSCDNCCKTKDYKTRDVTDDVKSIVRFVQE 1090

[Close]

BLAST of ATP-dependent DNA helicase vs. Ensembl Human
Match: BLM (BLM RecQ like helicase [Source:HGNC Symbol;Acc:HGNC:1058])

HSP 1 Score: 287.73 bits (735), Expect = 1.733e-82
Identity = 167/449 (37.19%), Postives = 247/449 (55.01%), Query Frame = 1

Query:  253 NFPWSSNIKKLLQDKFKIKNFKSLQLKTINATLDKLDCIFISSPGSGKSLCYQLASMIS-GFTLVIAPLGSLIQDQMIVSEKFGISCISLDSNSSVKIQNEIFKAM-ETDPVDNVTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRLVIDEIHCCSELSHDFRQDYKNLHGLKSLYPNLPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEVKFLSNEKKEGEEICKLIKSRFDGQSGIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNEN-CKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFWKLAEYFKIGSNIFTEKSG--------IPNLNIMNRYILDDCTCKRVSLSSILDEK-FTVNDCKNMCSVCADTESEMSSIDIADVYKSALTIIKNIEK 1563
            +FP +  + K+   KF + NF++ QL+ INA L   DC  +   G GKSLCYQL + +S G T+VI+PL SLI DQ+       I    L  + +      I+  + + DP+     KL+Y TP+KI  S +L   +E  Y  K L R VIDE HC S+  HDFRQDYK ++ L+  +P++PV+ LTATAN  V  DI T L +     V   ++NR N+ Y V      KK   +  + I+      SGI++C ++++C+ + + L  +G+ A +Y+  L    + ++  KW+N++ C+VI AT AFGMGIDKP+VRFVIH S+ KS+E YYQESGRAGRDG+ S C+LF+   +  ++   I  EK G          NL  M  Y  +   C+R+ L +   E  F  + CK    V  D   +       DV     +I++ +++
Sbjct:  648 SFPHTKEMMKIFHKKFGLHNFRTNQLEAINAALLGEDCFILMPTGGGKSLCYQLPACVSPGVTVVISPLRSLIVDQVQKLTSLDIPATYLTGDKTDSEATNIYLQLSKKDPI----IKLLYVTPEKICASNRLISTLENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPSVPVMALTATANPRVQKDILTQLKILRP-QVFSMSFNRHNLKYYV-LPKKPKKVAFDCLEWIRKHHPYDSGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVICATIAFGMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKRLIMMEKDGNHHTRETHFNNLYSMVHYCENITECRRIQLLAYFGENGFNPDFCKKHPDVSCDNCCKTKDYKTRDVTDDVKSIVRFVQE 1090

[Close]

BLAST of ATP-dependent DNA helicase vs. Ensembl Human
Match: BLM (BLM RecQ like helicase [Source:HGNC Symbol;Acc:HGNC:1058])

HSP 1 Score: 287.345 bits (734), Expect = 1.822e-82
Identity = 169/449 (37.64%), Postives = 249/449 (55.46%), Query Frame = 1

Query:  253 NFPWSSNIKKLLQDKFKIKNFKSLQLKTINATLDKLDCIFISSPGSGKSLCYQLASMIS-GFTLVIAPLGSLIQDQMIVSEKFGISCISLDSNSSVKIQNEIFKAM-ETDPVDNVTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRLVIDEIHCCSELSHDFRQDYKNLHGLKSLYPNLPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEVKFLSNEKKEGEEICKLIKSRFDGQSGIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNEN-CKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFWKLAEYFKIGSNIFTEKSG--------IPNLNIMNRYILDDCTCKRVSLSSILDEK-FTVNDCKNM----CSVCADTESEMSSIDIADVYKSALTIIK 1551
            +FP +  + K+   KF + NF++ QL+ INA L   DC  +   G GKSLCYQL + +S G T+VI+PL SLI DQ+       I    L  + +      I+  + + DP+     KL+Y TP+KI  S +L   +E  Y  K L R VIDE HC S+  HDFRQDYK ++ L+  +P++PV+ LTATAN  V  DI T L +     V   ++NR N+ Y V      KK   +  + I+      SGI++C ++++C+ + + L  +G+ A +Y+  L    + ++  KW+N++ C+VI AT AFGMGIDKP+VRFVIH S+ KS+E YYQESGRAGRDG+ S C+LF+   +  ++   I  EK G          NL  M  Y  +   C+R+ L +   E  F  + CK      C  C  T+ +  + D+ D  KS +  ++
Sbjct:  648 SFPHTKEMMKIFHKKFGLHNFRTNQLEAINAALLGEDCFILMPTGGGKSLCYQLPACVSPGVTVVISPLRSLIVDQVQKLTSLDIPATYLTGDKTDSEATNIYLQLSKKDPI----IKLLYVTPEKICASNRLISTLENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPSVPVMALTATANPRVQKDILTQLKILRP-QVFSMSFNRHNLKYYV-LPKKPKKVAFDCLEWIRKHHPYDSGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVICATIAFGMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKRLIMMEKDGNHHTRETHFNNLYSMVHYCENITECRRIQLLAYFGENGFNPDFCKKHPDVSCDNCCKTK-DYKTRDVTDDVKSIVRFVQ 1089

[Close]

BLAST of ATP-dependent DNA helicase vs. Ensembl Celegans
Match: K02F3.12 (Putative ATP-dependent DNA helicase Q1 [Source:UniProtKB/Swiss-Prot;Acc:Q9TXJ8])

HSP 1 Score: 402.519 bits (1033), Expect = 1.676e-131
Identity = 230/610 (37.70%), Postives = 357/610 (58.52%), Query Frame = 1

Query:  109 EIDKRIVAIDNEIKTLTHEKEDLIKKK----KQLSISTKGHSITSNKDYGKENFPWSSNIKKLLQDKFKIKNFKSLQLKTINATLDKLDCIFISSPGSGKSLCYQLASMIS-GFTLVIAPLGSLIQDQMIVSEKFGISCISLDSNSSVKIQNEIFKAMETDPVDN--VTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRLVIDEIHCCSELSHDFRQDYKNLHGLKSLYPNLPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEV-KFLSNEKKEGEEICKLIKSRFDGQSGIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNENCKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFWKLAEYFKIGSNIFTEKSGIPNLNIMNRYILDDCTCKRVSLSSILDEKFTVNDCKNMCSVCAD-----TESEMSSIDIADVYKSALTIIK---NIEKTKNPKITGKKIISELANQMSLYFADLANRFPGIDYKLFLDKAFCHLVLVGYLKLDYSFGSFSNFTYVIAGSKTLKSNEKIDIPIRIAKSDKMRNLVQNVKQNESSNVKK 1890
            ++D  I  ID +I  L  +K +L +K+    +++ + T   S      + ++ FPWS    K+L+++F ++ F+ LQ   INA + K D + I S G GKSLCYQL ++++ G  LV++PL SL++DQ++     GI   SL++N+S     E  K +E D + N    ++L+Y TP+K++ SKK+   +EK+     L  + IDE+HCCS+  HDFR DY  L+ LK  +  +P+LGLTATA ++V++D+K  L + +  L  +  +NRSN+ Y+V +   +E +  EEI K IK  F GQ+GI++C ++ DCE +   L ++GI A  Y+  +    +   H  W++   +VIVAT AFGMGIDKPNVRFVIH S+ KS+ENYYQESGRAGRDG+ + CIL+++LA+ FK  S +  E++GI NL  M RY  D  TC+RV L+   +E +  + C+  C  C +       S   S D+++  K+ + II+   N  K  + +ITG K++ EL          L  +  G   + F +K   +L+L GYL+ D+ +  +S  +YV+ GSK    N K  I +R  +  K R      K+  SS+V++
Sbjct:   15 DLDGEIGQIDQQISQLRRKKSELTQKRQAIERKIELKTNEDSDVVTDRWDRDGFPWSDEATKILKEQFHLEKFRPLQRAAINAVMSKEDAVVILSTGGGKSLCYQLPALLANGLALVVSPLISLVEDQILQLRSLGIDSSSLNANTS----KEEAKRVE-DAITNKDSKFRLLYVTPEKLAKSKKMMNKLEKSLSVGFLKLIAIDEVHCCSQWGHDFRTDYSFLNVLKRQFKGVPILGLTATATSNVLDDVKDMLGIQA-ALTFRAGFNRSNLKYKVVQKPGSEDECTEEIAKTIKRDFAGQTGIIYCLSRNDCEKVAKALKSHGIKAKHYHAYMEPVDRSGAHQGWISGKIQVIVATVAFGMGIDKPNVRFVIHHSLPKSIENYYQESGRAGRDGQPATCILYYRLADIFKQSSMVQQERTGIQNLYNMVRYAADSSTCRRVKLAEHFEEAWEPSWCQKQCDTCENGNGFVGTSSKESTDVSEAAKTTVRIIEEHLNSAKDGSGRITGNKLV-EL----------LTKKLKGSRNREFCEKLIVNLLLEGYLQEDFHYTVYSVISYVVIGSKWRVYNGKDAIKMRHVEESKSR------KRKASSSVEE 601

[Close]

Query:  109 EIDKRIVAIDNEIKTLTHEKEDLIKKK----KQLSISTKGHSITSNKDYGKENFPWSSNIKKLLQDKFKIKNFKSLQLKTINATLDKLDCIFISSPGSGKSLCYQLASMIS-GFTLVIAPLGSLIQDQMIVSEKFGISCISLDSNSSVKIQNEIFKAMETDPVDN--VTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRLVIDEIHCCSELSHDFRQDYKNLHGLKSLYPNLPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEV-KFLSNEKKEGEEICKLIKSRFDGQSGIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNENCKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFWKLAEYFKIGSNIFTEKSGIPNLNIMNRYILDDCTCKRVSLSSILDEKFTVNDCKNMCSVCAD-----TESEMSSIDIADVYKSALTIIK---NIEKTKNPKITGKKIISELANQMSLYFADLANRFPGIDYKLFLDKAFCHLVLVGYLKLDYSFGSFSNFTYVIAGSKTLKSNEKIDIPIRIAKSDKMRNLVQNVKQNESSNVKK 1890
            ++D  I  ID +I  L  +K +L +K+    +++ + T   S      + ++ FPWS    K+L+++F ++ F+ LQ   INA + K D + I S G GKSLCYQL ++++ G  LV++PL SL++DQ++     GI   SL++N+S     E  K +E D + N    ++L+Y TP+K++ SKK+   +EK+     L  + IDE+HCCS+  HDFR DY  L+ LK  +  +P+LGLTATA ++V++D+K  L + +  L  +  +NRSN+ Y+V +   +E +  EEI K IK  F GQ+GI++C ++ DCE +   L ++GI A  Y+  +    +   H  W++   +VIVAT AFGMGIDKPNVRFVIH S+ KS+ENYYQESGRAGRDG+ + CIL+++LA+ FK  S +  E++GI NL  M RY  D  TC+RV L+   +E +  + C+  C  C +       S   S D+++  K+ + II+   N  K  + +ITG K++ EL          L  +  G   + F +K   +L+L GYL+ D+ +  +S  +YV+ GSK    N K  I +R  +  K R      K+  SS+V++
Sbjct:   15 DLDGEIGQIDQQISQLRRKKSELTQKRQAIERKIELKTNEDSDVVTDRWDRDGFPWSDEATKILKEQFHLEKFRPLQRAAINAVMSKEDAVVILSTGGGKSLCYQLPALLANGLALVVSPLISLVEDQILQLRSLGIDSSSLNANTS----KEEAKRVE-DAITNKDSKFRLLYVTPEKLAKSKKMMNKLEKSLSVGFLKLIAIDEVHCCSQWGHDFRTDYSFLNVLKRQFKGVPILGLTATATSNVLDDVKDMLGIQA-ALTFRAGFNRSNLKYKVVQKPGSEDECTEEIAKTIKRDFAGQTGIIYCLSRNDCEKVAKALKSHGIKAKHYHAYMEPVDRSGAHQGWISGKIQVIVATVAFGMGIDKPNVRFVIHHSLPKSIENYYQESGRAGRDGQPATCILYYRLADIFKQSSMVQQERTGIQNLYNMVRYAADSSTCRRVKLAEHFEEAWEPSWCQKQCDTCENGNGFVGTSSKESTDVSEAAKTTVRIIEEHLNSAKDGSGRITGNKLV-EL----------LTKKLKGSRNREFCEKLIVNLLLEGYLQEDFHYTVYSVISYVVIGSKWRVYNGKDAIKMRHVEESKSR------KRKASSSVEE 601

[Close]

BLAST of ATP-dependent DNA helicase vs. Ensembl Celegans
Match: K02F3.12 (Putative ATP-dependent DNA helicase Q1 [Source:UniProtKB/Swiss-Prot;Acc:Q9TXJ8])

HSP 1 Score: 402.134 bits (1032), Expect = 4.620e-131
Identity = 230/610 (37.70%), Postives = 357/610 (58.52%), Query Frame = 1

Query:  109 EIDKRIVAIDNEIKTLTHEKEDLIKKK----KQLSISTKGHSITSNKDYGKENFPWSSNIKKLLQDKFKIKNFKSLQLKTINATLDKLDCIFISSPGSGKSLCYQLASMIS-GFTLVIAPLGSLIQDQMIVSEKFGISCISLDSNSSVKIQNEIFKAMETDPVDN--VTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRLVIDEIHCCSELSHDFRQDYKNLHGLKSLYPNLPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEV-KFLSNEKKEGEEICKLIKSRFDGQSGIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNENCKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFWKLAEYFKIGSNIFTEKSGIPNLNIMNRYILDDCTCKRVSLSSILDEKFTVNDCKNMCSVCAD-----TESEMSSIDIADVYKSALTIIK---NIEKTKNPKITGKKIISELANQMSLYFADLANRFPGIDYKLFLDKAFCHLVLVGYLKLDYSFGSFSNFTYVIAGSKTLKSNEKIDIPIRIAKSDKMRNLVQNVKQNESSNVKK 1890
            ++D  I  ID +I  L  +K +L +K+    +++ + T   S      + ++ FPWS    K+L+++F ++ F+ LQ   INA + K D + I S G GKSLCYQL ++++ G  LV++PL SL++DQ++     GI   SL++N+S     E  K +E D + N    ++L+Y TP+K++ SKK+   +EK+     L  + IDE+HCCS+  HDFR DY  L+ LK  +  +P+LGLTATA ++V++D+K  L + +  L  +  +NRSN+ Y+V +   +E +  EEI K IK  F GQ+GI++C ++ DCE +   L ++GI A  Y+  +    +   H  W++   +VIVAT AFGMGIDKPNVRFVIH S+ KS+ENYYQESGRAGRDG+ + CIL+++LA+ FK  S +  E++GI NL  M RY  D  TC+RV L+   +E +  + C+  C  C +       S   S D+++  K+ + II+   N  K  + +ITG K++ EL          L  +  G   + F +K   +L+L GYL+ D+ +  +S  +YV+ GSK    N K  I +R  +  K R      K+  SS+V++
Sbjct:   38 DLDGEIGQIDQQISQLRRKKSELTQKRQAIERKIELKTNEDSDVVTDRWDRDGFPWSDEATKILKEQFHLEKFRPLQRAAINAVMSKEDAVVILSTGGGKSLCYQLPALLANGLALVVSPLISLVEDQILQLRSLGIDSSSLNANTS----KEEAKRVE-DAITNKDSKFRLLYVTPEKLAKSKKMMNKLEKSLSVGFLKLIAIDEVHCCSQWGHDFRTDYSFLNVLKRQFKGVPILGLTATATSNVLDDVKDMLGIQA-ALTFRAGFNRSNLKYKVVQKPGSEDECTEEIAKTIKRDFAGQTGIIYCLSRNDCEKVAKALKSHGIKAKHYHAYMEPVDRSGAHQGWISGKIQVIVATVAFGMGIDKPNVRFVIHHSLPKSIENYYQESGRAGRDGQPATCILYYRLADIFKQSSMVQQERTGIQNLYNMVRYAADSSTCRRVKLAEHFEEAWEPSWCQKQCDTCENGNGFVGTSSKESTDVSEAAKTTVRIIEEHLNSAKDGSGRITGNKLV-EL----------LTKKLKGSRNREFCEKLIVNLLLEGYLQEDFHYTVYSVISYVVIGSKWRVYNGKDAIKMRHVEESKSR------KRKASSSVEE 624

[Close]

BLAST of ATP-dependent DNA helicase vs. Ensembl Celegans
Match: him-6 (Bloom syndrome protein homolog [Source:UniProtKB/Swiss-Prot;Acc:O18017])

HSP 1 Score: 263.077 bits (671), Expect = 1.633e-75
Identity = 154/455 (33.85%), Postives = 244/455 (53.63%), Query Frame = 1

Query:  286 LQDKFKIKNFKSLQLKTINATLDKLDCIFISSPGSGKSLCYQLASMI-SGFTLVIAPLGSLIQDQMIVSEKFGISCISLDSNSSVKIQNEIFKAMETDPVDNVTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRLVIDEIHCCSELSHDFRQDYKNLHGLKSLY--PNLPVLGLTATANNSVINDIKTTLNL-NSDCLVHKDNYNRSNIFYEVKFLSNEKKEGEEICKLIKSRFDGQSGIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNENCKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFWKLAEYFKIGSNI--FTEKSGIPNLNIMN-----RYILDDCTCKRVSLSSILDEKFTVNDCKN---MCSVCADTESEMSSIDIADVYKSALTIIKNIEKTKNPKITGKKIISEL 1608
            L+ KF    F+  Q + I +TL   D   +   G+GKSLCYQL ++I  G T+V++PL SLI+DQ +  ++ GI C +L ++     Q +I+  + +    N + KL+Y TP+KIS S +L       +    L R VIDE HC S+  HDFR DY  L  L+  Y  P +P++ LTATA   ++ D +  L + NS   +   ++ R N+ Y++  +    +    + + +K  + G+SGIV+C ++K+CE +   L   G+ A  Y+  L  +++  +   W+     VI AT AFGMGIDKP+VRFVIH S+ KS+E YYQE+GRAGRDG  S C++ +   +  ++   I      +G+ ++++ N      Y  +   C+R  L     E +    C+N    C +C        +I + DV   AL+I+K + + +   +   K ISEL
Sbjct:  239 LKSKFGFNQFRHRQKQCILSTLMGHDTFVLMPTGAGKSLCYQLPAVILPGVTVVVSPLRSLIEDQKMKMKELGIGCEALTADLGAPAQEKIYAELGSG---NPSIKLLYVTPEKISASGRLNSVFFDLHRRGLLARFVIDEAHCVSQWGHDFRPDYTKLSSLREKYANPPVPIIALTATATPKIVTDARDHLKMQNSKLFI--SSFVRDNLKYDL--IPKAARSLINVVEKMKQLYPGKSGIVYCLSRKECETVQMMLTKAGLSAEVYHAGLNDNLRVSVQRSWIANKFDVICATIAFGMGIDKPDVRFVIHYSLPKSIEGYYQETGRAGRDGMPSYCLMLYSYHDSIRLRRMIEEGNTTTGVRSMHLNNVLQVVAYCENVSVCRRKMLVEHFGEVYDEQSCRNSKTPCDICERQRKNAEAIRLFDVSTDALSILKCLPRMQKATL---KYISEL 683

[Close]

BLAST of ATP-dependent DNA helicase vs. Ensembl Celegans
Match: rcq-5 (ATP-dependent DNA helicase [Source:UniProtKB/TrEMBL;Acc:Q19046])

HSP 1 Score: 212.616 bits (540), Expect = 1.673e-58
Identity = 148/464 (31.90%), Postives = 235/464 (50.65%), Query Frame = 1

Query:  280 KLLQDKFKIKNFKS-LQLKTINATLDKLDCIFISSP-GSGKSLCYQLASMI-SGFTLVIAPLGSLIQDQMIVSEKFGISCISLDSNSSVKIQNEIFKAMETDPVDNVTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVR-LVIDEIHCCSELSHDFRQDYKNLHGLKSLYPNLPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEVKF-----LSNEKKEGEEICKLI----------------------KSRFDGQSGIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNENCKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFW-----------------KLAEYFKIGSNIFTEKS--GIPNLNIMNRYILDDC---TCKRVSLSSILDEKFTVNDCKNMCSVCADTESEMSSID 1512
            K+  + F  K ++S LQ++ IN  L +   +++S P G+GKSLCYQL +++  G T+VI+PL +L++DQ+   ++ GI C +L+S  +   ++ I   +  +     T +++Y T + ++     TK +     ++ ++R +V+DE HC ++  HDFR DY  L  L+ + P +P + LTATAN    +DI   L L +        Y R N+FY+V        + E      I K +                      K  F G S IV+C ++ +C  +   L   GI A +Y+  LG   + ++  KW+N    V+ AT AFGMGIDKP+VR VIH S S++L  YYQE+GRAGRDGKRS C +++                 KL E  K  +N   EK+   I ++      +L+ C    C+ VS++S  D+      CK  C  C D    + +++
Sbjct:  167 KVFLELFCHKKYRSRLQMQAINCILKRKCDVYVSLPTGAGKSLCYQLPAVVHGGITVVISPLIALMKDQISSLKRKGIPCETLNSTLTTVERSRIMGELAKE---KPTIRMLYLTAEGVATDG--TKKLLNGLANRDVLRYIVVDEAHCVTQWGHDFRPDYLTLGSLRDVCPGVPWVALTATANAKAQDDIAFQLKLRNPESFKSGTY-RDNLFYDVAMRDHLATAPENHMASFITKCLTVDAKTSSSNLTKHEKAERSQNKKTFTG-SAIVYCRSRNECGQVAKMLEIAGIPAMAYHAGLGKKDRNEVQEKWMNNEIPVVAATVAFGMGIDKPDVRAVIHWSPSQNLAGYYQEAGRAGRDGKRSYCRIYYSKQDKNALNFLVSGELAKLREKAK-KNNAEGEKAEMQIKSIQTGLAKMLEYCESARCRHVSIASFFDDT-ECRPCKTNCDYCRDPTKTIRNVE 621

[Close]

BLAST of ATP-dependent DNA helicase vs. Ensembl Fly
Match: Blm (gene:FBgn0002906 transcript:FBtr0082434)

HSP 1 Score: 271.166 bits (692), Expect = 4.041e-77
Identity = 161/457 (35.23%), Postives = 251/457 (54.92%), Query Frame = 1

Query:  238 DYGKENFPWSSNIKKLLQDKFKIKNFKSLQLKTINATLDKLDCIFISSPGSGKSLCYQLASMIS-GFTLVIAPLGSLIQDQMIVSEKFGISCISLDSNSSVKIQNEIFKAMETDPVDNVTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRLVIDEIHCCSELSHDFRQDYKNLHGLKSLYPNLPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEVKFLSNEKKEG----EEICKLIKSRFDGQSGIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNENCKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFWKLAEYFKIGSNIFTEKS---GIPNLNIMNRY-ILDDCT----CKRVSLSSILDEKFTVNDC----KNMCSVCADTESEMSSIDIADVYKSALTIIKNI 1557
            ++  + F  S+ +   L   F +K+F+  QL+ INATL   DC  +   G GKSLCYQL ++++ G T+VI+PL SLI DQ+       I   SL     +     I++ +E+ P      KL+Y TP+KIS+S +    ++    +  + R VIDE HC S+  HDFR DYK L  LK  +PN+P + LTATA   V  DI   LNL  +C     ++NRSN+ Y V       K+G    ++I + I+S+    SGI++C ++K+C+  + ++  +G+ A SY+  L    ++     WL    +VI AT AFGMGIDKP+VRFV+H S+ KS+E YYQE+GRAGRDG  +DCIL++  ++  +I   + ++K+    +  +++ N Y I+  C     C+R        E FT   C    +  C  C +  +   ++D  +  + A   +K++
Sbjct:  713 EFDGQKFEHSTRLMHGLSYSFGLKSFRPNQLQVINATLLGNDCFVLMPTGGGKSLCYQLPAILTEGVTIVISPLKSLIFDQINKLASLDICAKSLSGEQKMADVMAIYRDLESQPP---MVKLLYVTPEKISSSARFQDTLDTLNSNNYISRFVIDEAHCVSQWGHDFRPDYKKLGVLKKRFPNVPTIALTATATPRVRLDILAQLNLK-NCKWFLSSFNRSNLRYRVL-----PKKGVSTLDDISRYIRSKPQHFSGIIYCLSRKECDETSKKMCKDGVRAVSYHAGLTDTDRESRQKDWLTGKMRVICATVAFGMGIDKPDVRFVLHYSLPKSIEGYYQEAGRAGRDGDVADCILYYNYSDMLRIKKMLDSDKALQYNVKKIHVDNLYRIVGYCENLTDCRRAQQLDYFGEHFTSEQCLENRETACDNCINKRA-YKAVDALEHARKAARAVKDL 1159

[Close]

BLAST of ATP-dependent DNA helicase vs. Ensembl Fly
Match: RecQ5 (gene:FBgn0027375 transcript:FBtr0100362)

HSP 1 Score: 190.66 bits (483), Expect = 6.942e-53
Identity = 133/465 (28.60%), Postives = 221/465 (47.53%), Query Frame = 1

Query:  268 SNIKKLLQDKFKIKNFKS-LQLKTINATLDKLDCIFISSP-GSGKSLCYQLASMIS--GFTLVIAPLGSLIQDQMIVSEKFGISCISLDSNSSVKIQNEI---FKAMETDPVDNVTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRLVIDEIHCCSELSHDFRQDYKNLHGLKSLYPNLPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEVKFLSNEKKEGEEICKLIK------------SRFDGQSGIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNENCKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFWKLAEYFKI--------------GSNIFTEKSGIPNLNIMNRYILDDCTCKRVSLSSILDEKFTVNDCKNMCSVCADTESEMSSIDI------ADVYKSALTI 1545
            S + + L+  F    FKS LQ K +   + K   +++S P GSGKSLC+QL  ++S    T+V +PL +LI+DQ+    K  +   SL+S  S K ++ +    KA+ T+       K +Y TP++ + +K     ++  +   +L    +DE HC S+  HDFR DY  L  L+S Y ++  L LTATA+  V  DI   L L+           R N+FY++ + ++ + + + +    +             +     GIV+C  +   E +   +   GI A +Y+  L    + ++   W+  +  +I ATN+FGMG+DKP+VRFVIH  + +++  YYQESGRAGRDG +S C L++   +   I              G      +  I     +  +  +  TC+    S    +     DC   C VC   +    +++I       D +KS +++
Sbjct:    5 SAVHEALKKHFGHSKFKSDLQEKAVKCAVKKKQDVYVSMPTGSGKSLCFQLPGLMSENQITIVFSPLLALIKDQIDHLTKLKVPADSLNSKMSTKERDRVIMDLKAVRTN------LKFLYITPEQAA-TKFFQDLLQTLHKHNKLAYFAVDEAHCVSQWGHDFRPDYLKLGELRSKYSDVIWLALTATASREVKEDIYKQLRLHQPVAQFSTPSFRKNLFYDIVYKNSIEDDFQHLADFARHCLGNPKEFKDTPKPQRGCGIVYCRTRDQVERMAIGVTKQGIGAVAYHAGLKTGERTEVQEAWMRGDQPIICATNSFGMGVDKPSVRFVIHWDVPQNVAAYYQESGRAGRDGLQSYCRLYYGREDVRSIRFLLQNDAHRARGRGDKELLTERAIKQFEKITEFC-ERTTCRHKLFSDFFGD--PTPDCSGQCDVCKRPKKAEKALEIFHRLCMDDAFKSHISL 459

[Close]

BLAST of ATP-dependent DNA helicase vs. Ensembl Fly
Match: RecQ5 (gene:FBgn0027375 transcript:FBtr0075714)

HSP 1 Score: 190.274 bits (482), Expect = 8.011e-53
Identity = 133/465 (28.60%), Postives = 221/465 (47.53%), Query Frame = 1

Query:  268 SNIKKLLQDKFKIKNFKS-LQLKTINATLDKLDCIFISSP-GSGKSLCYQLASMIS--GFTLVIAPLGSLIQDQMIVSEKFGISCISLDSNSSVKIQNEI---FKAMETDPVDNVTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRLVIDEIHCCSELSHDFRQDYKNLHGLKSLYPNLPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEVKFLSNEKKEGEEICKLIK------------SRFDGQSGIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNENCKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFWKLAEYFKI--------------GSNIFTEKSGIPNLNIMNRYILDDCTCKRVSLSSILDEKFTVNDCKNMCSVCADTESEMSSIDI------ADVYKSALTI 1545
            S + + L+  F    FKS LQ K +   + K   +++S P GSGKSLC+QL  ++S    T+V +PL +LI+DQ+    K  +   SL+S  S K ++ +    KA+ T+       K +Y TP++ + +K     ++  +   +L    +DE HC S+  HDFR DY  L  L+S Y ++  L LTATA+  V  DI   L L+           R N+FY++ + ++ + + + +    +             +     GIV+C  +   E +   +   GI A +Y+  L    + ++   W+  +  +I ATN+FGMG+DKP+VRFVIH  + +++  YYQESGRAGRDG +S C L++   +   I              G      +  I     +  +  +  TC+    S    +     DC   C VC   +    +++I       D +KS +++
Sbjct:    5 SAVHEALKKHFGHSKFKSDLQEKAVKCAVKKKQDVYVSMPTGSGKSLCFQLPGLMSENQITIVFSPLLALIKDQIDHLTKLKVPADSLNSKMSTKERDRVIMDLKAVRTN------LKFLYITPEQAA-TKFFQDLLQTLHKHNKLAYFAVDEAHCVSQWGHDFRPDYLKLGELRSKYSDVIWLALTATASREVKEDIYKQLRLHQPVAQFSTPSFRKNLFYDIVYKNSIEDDFQHLADFARHCLGNPKEFKDTPKPQRGCGIVYCRTRDQVERMAIGVTKQGIGAVAYHAGLKTGERTEVQEAWMRGDQPIICATNSFGMGVDKPSVRFVIHWDVPQNVAAYYQESGRAGRDGLQSYCRLYYGREDVRSIRFLLQNDAHRARGRGDKELLTERAIKQFEKITEFC-ERTTCRHKLFSDFFGD--PTPDCSGQCDVCKRPKKAEKALEIFHRLCMDDAFKSHISL 459

[Close]

BLAST of ATP-dependent DNA helicase vs. Ensembl Fly
Match: RecQ5 (gene:FBgn0027375 transcript:FBtr0075715)

HSP 1 Score: 190.274 bits (482), Expect = 3.129e-50
Identity = 134/466 (28.76%), Postives = 224/466 (48.07%), Query Frame = 1

Query:  268 SNIKKLLQDKFKIKNFKS-LQLKTINATLDKLDCIFISSP-GSGKSLCYQLASMIS--GFTLVIAPLGSLIQDQMIVSEKFGISCISLDSNSSVKIQNEI---FKAMETDPVDNVTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRLVIDEIHCCSELSHDFRQDYKNLHGLKSLYPNLPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEVKFLSNEKKEGEEICKLIK------------SRFDGQSGIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNENCKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFWKLAEYFKI---------------GSNIFTEKSGIPNLNIMNRYILDDCTCKRVSLSSILDEKFTVNDCKNMCSVCADTESEMSSIDI------ADVYKSALTI 1545
            S + + L+  F    FKS LQ K +   + K   +++S P GSGKSLC+QL  ++S    T+V +PL +LI+DQ+    K  +   SL+S  S K ++ +    KA+ T+       K +Y TP++ + +K     ++  +   +L    +DE HC S+  HDFR DY  L  L+S Y ++  L LTATA+  V  DI   L L+           R N+FY++ + ++ + + + +    +             +     GIV+C  +   E +   +   GI A +Y+  L    + ++   W+  +  +I ATN+FGMG+DKP+VRFVIH  + +++  YYQESGRAGRDG +S C L++   +   I                  + TE++ I     +  +  +  TC+    S    +     DC   C VC   +    +++I       D +KS +++
Sbjct:    5 SAVHEALKKHFGHSKFKSDLQEKAVKCAVKKKQDVYVSMPTGSGKSLCFQLPGLMSENQITIVFSPLLALIKDQIDHLTKLKVPADSLNSKMSTKERDRVIMDLKAVRTN------LKFLYITPEQAA-TKFFQDLLQTLHKHNKLAYFAVDEAHCVSQWGHDFRPDYLKLGELRSKYSDVIWLALTATASREVKEDIYKQLRLHQPVAQFSTPSFRKNLFYDIVYKNSIEDDFQHLADFARHCLGNPKEFKDTPKPQRGCGIVYCRTRDQVERMAIGVTKQGIGAVAYHAGLKTGERTEVQEAWMRGDQPIICATNSFGMGVDKPSVRFVIHWDVPQNVAAYYQESGRAGRDGLQSYCRLYYGREDVRSIRFLLQNDAHRARGRGDKELLTERA-IKQFEKITEFC-ERTTCRHKLFSDFFGD--PTPDCSGQCDVCKRPKKAEKALEIFHRLCMDDAFKSHISL 459

[Close]

BLAST of ATP-dependent DNA helicase vs. Ensembl Fly
Match: RecQ4 (gene:FBgn0040290 transcript:FBtr0076729)

HSP 1 Score: 142.124 bits (357), Expect = 2.355e-34
Identity = 114/371 (30.73%), Postives = 178/371 (47.98%), Query Frame = 1

Query:  298 FKIKNFKSLQLKTINATLDKLDCIFISSPGSGKSLCYQLASM-----ISGFTLVIAPLGSLIQDQMIVSEKFGISCISLDSNSSVKIQNEIFKAMETDPVDNVTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRLV-------IDEIHCCSELSHDFRQDYKNLHGLKSLYPNL---PVLGLTATA----NNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEVKFLSNEKKEGEEICKLIKSRFDG-QSGIVFCFNQKDCENL------------------TNELVNNGILASSYYGTLGYDIKKDIHNKWLNENCKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILF 1296
            F   NF+  Q + I  TL  L  +   S GSGKSLCYQL +      +   TLVI+PL SL++DQ+     F +    L +N +   + +I + +    +D     ++  +P+ +        A E+A G   ++R +       IDE HC S+ SH+FR  Y  L   K L  NL    VLGLTATA      S+IN +  +   + +  +  D     N+   V    +E ++   +  L   RF+  QS I++C  + +CE +                  T +       A  Y+  +    ++ +   +++   +++VAT AFGMGI+KP++R VIH +M ++ E+Y QE GRAGRDG  S C LF
Sbjct:  866 FGHTNFRKGQDRAIMRTLSGLSSLVTLSTGSGKSLCYQLPAYLYSRKVGAITLVISPLVSLMEDQVTGVPHF-LRAHCLHTNQTAPQRMKIQQMIANGEID-----ILLVSPEAVV-------AGERATGFGAILRQLPPIAFACIDEAHCVSQWSHNFRPSY--LMICKVLRKNLGVRTVLGLTATATLPTRVSIINHLGIS---DGERGIISDIPLPDNLVLSVS--KDENRDAALLQLLNSERFEPCQSIIIYCTRRDECERIAGFIRTCVQDRREPTQDQTKKRKRVNWQAEPYHAGMPASRRRTVQKAFMSNELRIVVATIAFGMGINKPDIRAVIHYNMPRNFESYVQEIGRAGRDGLPSHCHLF 1216

[Close]

BLAST of ATP-dependent DNA helicase vs. Ensembl Zebrafish
Match: recql (RecQ helicase-like [Source:ZFIN;Acc:ZDB-GENE-050809-134])

HSP 1 Score: 348.591 bits (893), Expect = 3.228e-110
Identity = 202/558 (36.20%), Postives = 315/558 (56.45%), Query Frame = 1

Query:  235 KDYGKENFPWSSNIKKLLQDKFKIKNFKSLQLKTINATLDKLDCIFISSPGSGKSLCYQLASMIS-GFTLVIAPLGSLIQDQMIVSEKFGISCISLDSNSSVKIQNEIFKAMETDPVDNVTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRLVIDEIHCCSELSHDFRQDYKNLHGLKSLYPNLPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEVKFLSNEKKEGEEICKLIKSRFDGQSGIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNENCKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFWKLAEYFKIGSNIFTEKSGIPNLNIMNRYILDDCTCKRVSLSSILDEKFTVNDCKNMCSVCADTESEMSSIDIADVYKSALTIIKNIEKTKNPKITGKKIISEL-----ANQMSLYFADLANRFPGIDYKLFLDKAFCHLVLVGYLKLDYSFGSFSNFTYVIAGSK-TLKSNEKIDIPIRIAKSDKMRNLVQNVKQNESSNVK 1887
            + Y   +F WS  ++  L + F++  F+ LQ   IN ++   D   +   G GKSLCYQL ++ S GFTLVIAPL SL++DQ++  +   +  ++L+++SS +    I   M TD   N  +KL+Y TP+KI+ SK L   +EKA+    L R+ +DE+HCCS+  HDFR DYK L  LK  +PN+P++GLTATA ++V+ D +  L +     +    +NR N++YEV+F  NE    ++I  LI+ R+  QSGIV+ F+QKD E +  EL    I+A  Y+  +    K  +H +W ++  +V+VAT AFGMGIDK +VRFVIH ++SKS+ENYYQESGRAGRD   +DCI+F+   + F+I + +  E +G   L+ M  Y  +   C+R  ++   DE +   +C  MC VC    ++  ++DI    +  L I++ +  + + K+T  K+         A Q  +      +R       L ++    HL+L GY   D+SF  ++   Y+  G K  L  N    I +++ +    ++ V+ V  +ESS  K
Sbjct:   72 QHYEDSDFSWSKEVQVNLCNIFQLSKFRPLQRAAINLSMSGKDLFLVMPTGRGKSLCYQLPALCSKGFTLVIAPLVSLMEDQLMYLQSVNVPAVTLNASSSKEDSKRILAGM-TD--KNSPFKLLYVTPEKIAKSKLLMSKLEKAFNMGLLARIAVDEVHCCSQWGHDFRPDYKLLGILKRQFPNVPLIGLTATATSNVLKDCQKILCVQEPVTLTAP-FNRPNLYYEVRFKDNEDCT-DQIASLIRGRYKNQSGIVYVFSQKDAEVVATELQKRDIVAQPYHANMEPSHKSLVHQRWSSKKIQVVVATVAFGMGIDKADVRFVIHHTISKSIENYYQESGRAGRDDSPADCIVFFGFMDIFRISTMVVMENTGQQKLHNMVAYCQNVDRCRRAMMAIHFDEVWNDEECNEMCDVCRHG-NDYITMDITQHARDVLHIVE-LASSMDEKLTPLKVCDAWLGKGPAKQRKMIKLTSLSR-------LEVESVIIHLLLHGYFSEDFSFTPYTTHFYLKLGRKAALLKNSGHSITMKMRRRGTSQSTVKKV--SESSGEK 613

[Close]

Query:  235 KDYGKENFPWSSNIKKLLQDKFKIKNFKSLQLKTINATLDKLDCIFISSPGSGKSLCYQLASMIS-GFTLVIAPLGSLIQDQMIVSEKFGISCISLDSNSSVKIQNEIFKAMETDPVDNVTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRLVIDEIHCCSELSHDFRQDYKNLHGLKSLYPNLPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEVKFLSNEKKEGEEICKLIKSRFDGQSGIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNENCKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFWKLAEYFKIGSNIFTEKSGIPNLNIMNRYILDDCTCKRVSLSSILDEKFTVNDCKNMCSVCADTESEMSSIDIADVYKSALTIIKNIEKTKNPKITGKKIISEL-----ANQMSLYFADLANRFPGIDYKLFLDKAFCHLVLVGYLKLDYSFGSFSNFTYVIAGSK-TLKSNEKIDIPIRIAKSDKMRNLVQNVKQNESSNVK 1887
            + Y   +F WS  ++  L + F++  F+ LQ   IN ++   D   +   G GKSLCYQL ++ S GFTLVIAPL SL++DQ++  +   +  ++L+++SS +    I   M TD   N  +KL+Y TP+KI+ SK L   +EKA+    L R+ +DE+HCCS+  HDFR DYK L  LK  +PN+P++GLTATA ++V+ D +  L +     +    +NR N++YEV+F  NE    ++I  LI+ R+  QSGIV+ F+QKD E +  EL    I+A  Y+  +    K  +H +W ++  +V+VAT AFGMGIDK +VRFVIH ++SKS+ENYYQESGRAGRD   +DCI+F+   + F+I + +  E +G   L+ M  Y  +   C+R  ++   DE +   +C  MC VC    ++  ++DI    +  L I++ +  + + K+T  K+         A Q  +      +R       L ++    HL+L GY   D+SF  ++   Y+  G K  L  N    I +++ +    ++ V+ V  +ESS  K
Sbjct:   72 QHYEDSDFSWSKEVQVNLCNIFQLSKFRPLQRAAINLSMSGKDLFLVMPTGRGKSLCYQLPALCSKGFTLVIAPLVSLMEDQLMYLQSVNVPAVTLNASSSKEDSKRILAGM-TD--KNSPFKLLYVTPEKIAKSKLLMSKLEKAFNMGLLARIAVDEVHCCSQWGHDFRPDYKLLGILKRQFPNVPLIGLTATATSNVLKDCQKILCVQEPVTLTAP-FNRPNLYYEVRFKDNEDCT-DQIASLIRGRYKNQSGIVYVFSQKDAEVVATELQKRDIVAQPYHANMEPSHKSLVHQRWSSKKIQVVVATVAFGMGIDKADVRFVIHHTISKSIENYYQESGRAGRDDSPADCIVFFGFMDIFRISTMVVMENTGQQKLHNMVAYCQNVDRCRRAMMAIHFDEVWNDEECNEMCDVCRHG-NDYITMDITQHARDVLHIVE-LASSMDEKLTPLKVCDAWLGKGPAKQRKMIKLTSLSR-------LEVESVIIHLLLHGYFSEDFSFTPYTTHFYLKLGRKAALLKNSGHSITMKMRRRGTSQSTVKKV--SESSGEK 613

[Close]

BLAST of ATP-dependent DNA helicase vs. Ensembl Zebrafish
Match: recql (RecQ helicase-like [Source:ZFIN;Acc:ZDB-GENE-050809-134])

HSP 1 Score: 344.739 bits (883), Expect = 1.188e-108
Identity = 201/558 (36.02%), Postives = 314/558 (56.27%), Query Frame = 1

Query:  235 KDYGKENFPWSSNIKKLLQDKFKIKNFKSLQLKTINATLDKLDCIFISSPGSGKSLCYQLASMIS-GFTLVIAPLGSLIQDQMIVSEKFGISCISLDSNSSVKIQNEIFKAMETDPVDNVTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRLVIDEIHCCSELSHDFRQDYKNLHGLKSLYPNLPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEVKFLSNEKKEGEEICKLIKSRFDGQSGIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNENCKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFWKLAEYFKIGSNIFTEKSGIPNLNIMNRYILDDCTCKRVSLSSILDEKFTVNDCKNMCSVCADTESEMSSIDIADVYKSALTIIKNIEKTKNPKITGKKIISEL-----ANQMSLYFADLANRFPGIDYKLFLDKAFCHLVLVGYLKLDYSFGSFSNFTYVIAGSK-TLKSNEKIDIPIRIAKSDKMRNLVQNVKQNESSNVK 1887
            + Y   +F WS  ++  L + F++  F+ LQ   IN ++   D   +   G GKSLCYQL ++ S GFTLVIAPL SL++DQ++  +   +  ++L+++SS +    I   M TD   N  +KL+Y TP+KI+ SK L   +EKA+    L R+ +DE+HCCS+  HDFR DYK L  LK  +PN+P++GLTATA ++V+ D +  L +     +    +NR N++YEV+F  NE    ++I  LI+ R+  QSGIV+ F+QKD E +  EL    I+A  Y+  +    K  +H +W ++  +V+VAT AFGMGIDK +VRFVIH ++SKS+ENYYQESGRAGRD   +DCI+F+   + F+I + +  E +G   L+ M  Y  +    +R  ++   DE +   +C  MC VC    ++  ++DI    +  L I++ +  + + K+T  K+         A Q  +      +R       L ++    HL+L GY   D+SF  ++   Y+  G K  L  N    I +++ +    ++ V+ V  +ESS  K
Sbjct:   72 QHYEDSDFSWSKEVQVNLCNIFQLSKFRPLQRAAINLSMSGKDLFLVMPTGRGKSLCYQLPALCSKGFTLVIAPLVSLMEDQLMYLQSVNVPAVTLNASSSKEDSKRILAGM-TD--KNSPFKLLYVTPEKIAKSKLLMSKLEKAFNMGLLARIAVDEVHCCSQWGHDFRPDYKLLGILKRQFPNVPLIGLTATATSNVLKDCQKILCVQEPVTLTAP-FNRPNLYYEVRFKDNEDCT-DQIASLIRGRYKNQSGIVYVFSQKDAEVVATELQKRDIVAQPYHANMEPSHKSLVHQRWSSKKIQVVVATVAFGMGIDKADVRFVIHHTISKSIENYYQESGRAGRDDSPADCIVFFGFMDIFRISTMVVMENTGQQKLHNMVAYCQNVDRQRRAMMAIHFDEVWNDEECNEMCDVCRHG-NDYITMDITQHARDVLHIVE-LASSMDEKLTPLKVCDAWLGKGPAKQRKMIKLTSLSR-------LEVESVIIHLLLHGYFSEDFSFTPYTTHFYLKLGRKAALLKNSGHSITMKMRRRGTSQSTVKKV--SESSGEK 613

[Close]

BLAST of ATP-dependent DNA helicase vs. Ensembl Zebrafish
Match: recql (RecQ helicase-like [Source:ZFIN;Acc:ZDB-GENE-050809-134])

HSP 1 Score: 335.495 bits (859), Expect = 7.355e-105
Identity = 202/582 (34.71%), Postives = 315/582 (54.12%), Query Frame = 1

Query:  235 KDYGKENFPWSSNIKKLLQDKFKIKNFKSLQLKTINATLDKLDCIFISSPGSGKSLCYQLASMIS-GFTLVIAPLGSLIQDQMIVSEKFGISCISLDSNSSVKIQNEIFKAMETDPVDNVTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRLVIDEIHCCSELSHDFRQ------------------------DYKNLHGLKSLYPNLPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEVKFLSNEKKEGEEICKLIKSRFDGQSGIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNENCKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFWKLAEYFKIGSNIFTEKSGIPNLNIMNRYILDDCTCKRVSLSSILDEKFTVNDCKNMCSVCADTESEMSSIDIADVYKSALTIIKNIEKTKNPKITGKKIISEL-----ANQMSLYFADLANRFPGIDYKLFLDKAFCHLVLVGYLKLDYSFGSFSNFTYVIAGSK-TLKSNEKIDIPIRIAKSDKMRNLVQNVKQNESSNVK 1887
            + Y   +F WS  ++  L + F++  F+ LQ   IN ++   D   +   G GKSLCYQL ++ S GFTLVIAPL SL++DQ++  +   +  ++L+++SS +    I   M TD   N  +KL+Y TP+KI+ SK L   +EKA+    L R+ +DE+HCCS+  HDFR                         DYK L  LK  +PN+P++GLTATA ++V+ D +  L +     +    +NR N++YEV+F  NE    ++I  LI+ R+  QSGIV+ F+QKD E +  EL    I+A  Y+  +    K  +H +W ++  +V+VAT AFGMGIDK +VRFVIH ++SKS+ENYYQESGRAGRD   +DCI+F+   + F+I + +  E +G   L+ M  Y  +   C+R  ++   DE +   +C  MC VC    ++  ++DI    +  L I++ +  + + K+T  K+         A Q  +      +R       L ++    HL+L GY   D+SF  ++   Y+  G K  L  N    I +++ +    ++ V+ V  +ESS  K
Sbjct:   72 QHYEDSDFSWSKEVQVNLCNIFQLSKFRPLQRAAINLSMSGKDLFLVMPTGRGKSLCYQLPALCSKGFTLVIAPLVSLMEDQLMYLQSVNVPAVTLNASSSKEDSKRILAGM-TD--KNSPFKLLYVTPEKIAKSKLLMSKLEKAFNMGLLARIAVDEVHCCSQWGHDFRPGEILFYLDRVKLLNPKLTMLFFSLDYKLLGILKRQFPNVPLIGLTATATSNVLKDCQKILCVQEPVTLTAP-FNRPNLYYEVRFKDNEDCT-DQIASLIRGRYKNQSGIVYVFSQKDAEVVATELQKRDIVAQPYHANMEPSHKSLVHQRWSSKKIQVVVATVAFGMGIDKADVRFVIHHTISKSIENYYQESGRAGRDDSPADCIVFFGFMDIFRISTMVVMENTGQQKLHNMVAYCQNVDRCRRAMMAIHFDEVWNDEECNEMCDVCRHG-NDYITMDITQHARDVLHIVE-LASSMDEKLTPLKVCDAWLGKGPAKQRKMIKLTSLSR-------LEVESVIIHLLLHGYFSEDFSFTPYTTHFYLKLGRKAALLKNSGHSITMKMRRRGTSQSTVKKV--SESSGEK 637

[Close]

BLAST of ATP-dependent DNA helicase vs. Ensembl Zebrafish
Match: blm (BLM RecQ like helicase [Source:ZFIN;Acc:ZDB-GENE-070702-5])

HSP 1 Score: 297.36 bits (760), Expect = 4.834e-86
Identity = 178/456 (39.04%), Postives = 249/456 (54.61%), Query Frame = 1

Query:  253 NFPWSSNIKKLLQDKFKIKNFKSLQLKTINATLDKLDCIFISSPGSGKSLCYQLASMIS-GFTLVIAPLGSLIQDQMIVSEKFGISCISLDSNSSVKIQNEIFKAM-ETDPVDNVTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRLVIDEIHCCSELSHDFRQDYKNLHGLKSLYPNLPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEVKFLSNEKKEGEEICKLIKSRFDGQSGIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNEN-CKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFWKLAEYFKIGSNIFTEKSG--------IPNLNIMNRYILDDCTCKRVSLSSILDEK-FTVNDCKN----MCSVCADTESEMSSIDIADVYKSALTIIKNIEKTKN 1572
            NFP S  + K+   KF +  F+  QL+ INA+L   D   +   G GKSLCYQL + +S G T+VI+PL SLI DQ+       I   SL  +        I+  +   DP      KL+Y TP+K+  S ++  A++  Y    L RLVIDE HC S+  HDFR DYK LH L+ ++PN+P++ LTATA   V  DI   L +     V   ++NR+N+ Y V      KK  EE  + IK  +   SGIV+C ++ DC+ L + L   GI A +Y+  L    ++ + NKW+N++ C+V+ AT AFGMGIDKP+VR+VIH S+ KS+E YYQESGRAGRDG+ S C+LF+  ++  +I   I  +K G        I NL+ M  +  +   C+R+ L +   E  F  + CK     +C  CA      S     DV K A  +  N EK  N
Sbjct:  659 NFPHSPEMMKIFHKKFGLHQFRFNQLEAINASLLGEDTFVLMPTGGGKSLCYQLPACVSAGVTVVISPLRSLIVDQVQKLTTLDICATSLSGDKKDSEAARIYMQLSRKDPA----IKLLYATPEKVCASGRMISALQNLYERGLLARLVIDEAHCVSQWGHDFRPDYKRLHELRRMFPNVPIMALTATATPRVQKDILNQLAMTRP-QVFTMSFNRNNLKYSV-LPKKPKKVDEECIQWIKKYYPRDSGIVYCLSRNDCDTLADSLQRAGIAALAYHAGLSDSDREYVQNKWINQDGCQVMCATIAFGMGIDKPDVRYVIHASLPKSVEGYYQESGRAGRDGEISHCVLFYSYSDVIRIKRLIAMDKDGNQQSKATHINNLHSMVHFCENVAECRRIQLLAYFGEHTFNTSFCKEHPEVICDNCARPNKYKSRNVTDDVKKIARFVQDNCEKVGN 1108

[Close]

BLAST of ATP-dependent DNA helicase vs. Ensembl Xenopus
Match: recql (RecQ like helicase [Source:NCBI gene;Acc:549070])

HSP 1 Score: 369.392 bits (947), Expect = 5.827e-118
Identity = 221/615 (35.93%), Postives = 343/615 (55.77%), Query Frame = 1

Query:  112 IDKRIVAIDNEIKTLTHEKEDLIKKKKQL-----------SISTKGHSITSNKDYGKENFPWSSNIKKLLQDKFKIKNFKSLQLKTINATLDKLDCIFISSPGSGKSLCYQLASMIS-GFTLVIAPLGSLIQDQMIVSEKFGISCISLDSNSSVKIQNEIFKAMETDPVDNVTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRLVIDEIHCCSELSHDFRQDYKNLHGLKSLYPNLPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEVKFLSNEKKEG-EEICKLIKSRFDGQSGIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNENCKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFWKLAEYFKIGSNIFTEKSGIPNLNIMNRYILDDCTCKRVSLSSILDEKFTVNDCKNMCSVCADTESEMSSIDIADVYKSALTIIKNIEKTKNPKITGKKIISELANQMSLYFADLANRFPGIDYKLF----LDKAFCHLVLVGYLKLDYSFGSFSNFTYVIAGSKT--LKSNE-KIDIPIRI----AKSDKMRNLVQNVKQNESSNV 1884
            +   + A++ +++ L   +++LI++K+ L              T      S +++ KE+F WS  I+  L + F++++F+SLQL+TINAT+   D   I   G GKSLCYQL ++ S GFTLVI PL SL++DQ++V ++ G+S  SL+++SS +    +   M      N   KL+Y TP+KI+ SK     +EKAY    L R+ +DE+HCCS+  HDFR DYK L  LK  +PN P++GLTATA   V+ D +  L +    L    ++NR N+FYEV+   +  ++   +I KLI SR+ GQSGI++CF+QKD E++T  L   GI A +Y+  +    K  +H KW     +++VAT AFGMGIDKP+VRFVIH SMSKS+ENYYQESGRA        CI  W+     ++ S +  E  G   L  M  Y      C+RV ++   DE +    C  MC  C ++E      DI    +  + I++   +  + K+T  K++     +     A L  R PG+         +++   HL+L  +L+ D+SF +++  +Y+  G K   L+S++  I +P+R     A +DK+++  Q+  Q+ +  V
Sbjct:   17 VSSELQAVEIQLQELLERQQELIQRKRLLNKKIQRLSEDSGPGTSAGGGDSAENWQKEDFLWSQKIRDALCNSFQLRSFRSLQLETINATMAGRDVFLIMPTGGGKSLCYQLPAVCSDGFTLVICPLVSLMEDQLMVLDRLGVSATSLNASSSKEHVKWVHGEMTNK---NSRLKLLYVTPEKIAKSKLFMSRLEKAYQAGLLARVAVDEVHCCSQWGHDFRPDYKTLGILKRQFPNSPLIGLTATATTHVLKDAQKILCVPKP-LTFTASFNRPNLFYEVRLKPSSSQDFIADIVKLINSRYRGQSGIIYCFSQKDSEHVTMSLQKLGIRAGTYHANMEPRDKTKVHTKWTANEIQIVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRA------VLCI-DWRPPSSLRLSSMVVMENVGQKKLYEMVGYCQSPDRCRRVLIAQHFDEVWDSAKCNKMCDNC-NSEGGWEKADITPYCRDIVKILEQANQM-DEKLTPLKLMDAWVGK---GVAKL--RVPGVRPPQLPRPEIERIIAHLLLQQFLREDFSFTAYATISYIKRGPKVDLLRSDKYAICLPMRSGGAGAGADKVKSPQQSTSQSLAPKV 613

[Close]

BLAST of ATP-dependent DNA helicase vs. Ensembl Xenopus
Match: recql (RecQ like helicase [Source:NCBI gene;Acc:549070])

HSP 1 Score: 365.54 bits (937), Expect = 3.014e-117
Identity = 220/597 (36.85%), Postives = 334/597 (55.95%), Query Frame = 1

Query:  133 IDNEIKTLTHEKEDLIKKKKQL-----------SISTKGHSITSNKDYGKENFPWSSNIKKLLQDKFKIKNFKSLQLKTINATLDKLDCIFISSPGSGKSLCYQLASMIS-GFTLVIAPLGSLIQDQMIVSEKFGISCISLDSNSSVKIQNEIFKAMETDPVDNVTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRLVIDEIHCCSELSHDFRQDYKNLHGLKSLYPNLPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEVKFLSNEKKEG-EEICKLIKSRFDGQSGIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNENCKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFWKLAEYFKIGSNIFTEKSGIPNLNIMNRYILDDCTCKRVSLSSILDEKFTVNDCKNMCSVCADTESEMSSIDIADVYKSALTIIKNIEKTK--NPKITGKKIISELANQMSLYFADLANRFPGIDYKLF----LDKAFCHLVLVGYLKLDYSFGSFSNFTYVIAGSKT--LKSNE-KIDIPIRI----AKSDKMRN 1845
            ++ +++ L   +++LI++K+ L              T      S +++ KE+F WS  I+  L + F++++F+SLQL+TINAT+   D   I   G GKSLCYQL ++ S GFTLVI PL SL++DQ++V ++ G+S  SL+++SS +    +   M      N   KL+Y TP+KI+ SK     +EKAY    L R+ +DE+HCCS+  HDFR DYK L  LK  +PN P++GLTATA   V+ D +  L +    L    ++NR N+FYEV+   +  ++   +I KLI SR+ GQSGI++CF+QKD E++T  L   GI A +Y+  +    K  +H KW     +++VAT AFGMGIDKP+VRFVIH SMSKS+ENYYQESGRA        CI  W+     ++ S +  E  G   L  M  Y      C+RV ++   DE +    C  MC  C       +S + AD+      I+K +E+    + K+T  K++     +     A L  R PG+         +++   HL+L  +L+ D+SF +++  +Y+  G K   L+S++  I +P+R     A +DK+R 
Sbjct:    1 VEIQLQELLERQQELIQRKRLLNKKIQRLSEDSGPGTSAGGGDSAENWQKEDFLWSQKIRDALCNSFQLRSFRSLQLETINATMAGRDVFLIMPTGGGKSLCYQLPAVCSDGFTLVICPLVSLMEDQLMVLDRLGVSATSLNASSSKEHVKWVHGEMTNK---NSRLKLLYVTPEKIAKSKLFMSRLEKAYQAGLLARVAVDEVHCCSQWGHDFRPDYKTLGILKRQFPNSPLIGLTATATTHVLKDAQKILCVPKP-LTFTASFNRPNLFYEVRLKPSSSQDFIADIVKLINSRYRGQSGIIYCFSQKDSEHVTMSLQKLGIRAGTYHANMEPRDKTKVHTKWTANEIQIVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRA------VLCI-DWRPPSSLRLSSMVVMENVGQKKLYEMVGYCQSPDRCRRVLIAQHFDEVWDSAKCNKMCDNC-------NSWEKADITPYCRDIVKILEQANQMDEKLTPLKLMDAWVGKG---VAKL--RVPGVRPPQLPRPEIERIIAHLLLQQFLREDFSFTAYATISYIKRGPKVDLLRSDKYAICLPMRSGGAGAGADKVRG 574

[Close]

BLAST of ATP-dependent DNA helicase vs. Ensembl Xenopus
Match: recql (RecQ like helicase [Source:NCBI gene;Acc:549070])

HSP 1 Score: 363.614 bits (932), Expect = 2.777e-116
Identity = 210/574 (36.59%), Postives = 320/574 (55.75%), Query Frame = 1

Query:  112 IDKRIVAIDNEIKTLTHEKEDLIKKKKQL-----------SISTKGHSITSNKDYGKENFPWSSNIKKLLQDKFKIKNFKSLQLKTINATLDKLDCIFISSPGSGKSLCYQLASMIS-GFTLVIAPLGSLIQDQMIVSEKFGISCISLDSNSSVKIQNEIFKAMETDPVDNVTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRLVIDEIHCCSELSHDFRQDYKNLHGLKSLYPNLPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEVKFLSNEKKEG-EEICKLIKSRFDGQSGIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNENCKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFWKLAEYFKIGSNIFTEKSGIPNLNIMNRYILDDCTCKRVSLSSILDEKFTVNDCKNMCSVCADTESEMSSIDIADVYKSALTIIKNIEKTKNPKITGKKIISELANQMSLYFADLANRFPGIDYKLF----LDKAFCHLVLVGYLKLDYSFGSFSNFTYVIAGSKT 1782
            +   + A++ +++ L   +++LI++K+ L              T      S +++ KE+F WS  I+  L + F++++F+SLQL+TINAT+   D   I   G GKSLCYQL ++ S GFTLVI PL SL++DQ++V ++ G+S  SL+++SS +    +   M      N   KL+Y TP+KI+ SK     +EKAY    L R+ +DE+HCCS+  HDFR DYK L  LK  +PN P++GLTATA   V+ D +  L +    L    ++NR N+FYEV+   +  ++   +I KLI SR+ GQSGI++CF+QKD E++T  L   GI A +Y+  +    K  +H KW     +++VAT AFGMGIDKP+VRFVIH SMSKS+ENYYQESGRA        CI  W+     ++ S +  E  G   L  M  Y      C+RV ++   DE +    C  MC  C ++E      DI    +  + I++   +  + K+T  K++     +     A L  R PG+         +++   HL+L  +L+ D+SF +++  +Y+  G K 
Sbjct:   14 VSSELQAVEIQLQELLERQQELIQRKRLLNKKIQRLSEDSGPGTSAGGGDSAENWQKEDFLWSQKIRDALCNSFQLRSFRSLQLETINATMAGRDVFLIMPTGGGKSLCYQLPAVCSDGFTLVICPLVSLMEDQLMVLDRLGVSATSLNASSSKEHVKWVHGEMTNK---NSRLKLLYVTPEKIAKSKLFMSRLEKAYQAGLLARVAVDEVHCCSQWGHDFRPDYKTLGILKRQFPNSPLIGLTATATTHVLKDAQKILCVPKP-LTFTASFNRPNLFYEVRLKPSSSQDFIADIVKLINSRYRGQSGIIYCFSQKDSEHVTMSLQKLGIRAGTYHANMEPRDKTKVHTKWTANEIQIVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRA------VLCI-DWRPPSSLRLSSMVVMENVGQKKLYEMVGYCQSPDRCRRVLIAQHFDEVWDSAKCNKMCDNC-NSEGGWEKADITPYCRDIVKILEQANQM-DEKLTPLKLMDAWVGKG---VAKL--RVPGVRPPQLPRPEIERIIAHLLLQQFLREDFSFTAYATISYIKRGPKV 569

[Close]

BLAST of ATP-dependent DNA helicase vs. Ensembl Xenopus
Match: recql (RecQ like helicase [Source:NCBI gene;Acc:549070])

HSP 1 Score: 363.229 bits (931), Expect = 2.859e-116
Identity = 216/584 (36.99%), Postives = 328/584 (56.16%), Query Frame = 1

Query:  133 IDNEIKTLTHEKEDLIKKKKQL-----------SISTKGHSITSNKDYGKENFPWSSNIKKLLQDKFKIKNFKSLQLKTINATLDKLDCIFISSPGSGKSLCYQLASMIS-GFTLVIAPLGSLIQDQMIVSEKFGISCISLDSNSSVKIQNEIFKAMETDPVDNVTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRLVIDEIHCCSELSHDFRQDYKNLHGLKSLYPNLPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEVKFLSNEKKEG-EEICKLIKSRFDGQSGIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNENCKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFWKLAEYFKIGSNIFTEKSGIPNLNIMNRYILDDCTCKRVSLSSILDEKFTVNDCKNMCSVCADTESEMSSIDIADVYKSALTIIKNIEKTK--NPKITGKKIISELANQMSLYFADLANRFPGIDYKLF----LDKAFCHLVLVGYLKLDYSFGSFSNFTYVIAGSKT--LKSNE-KIDIPIR 1818
            ++ +++ L   +++LI++K+ L              T      S +++ KE+F WS  I+  L + F++++F+SLQL+TINAT+   D   I   G GKSLCYQL ++ S GFTLVI PL SL++DQ++V ++ G+S  SL+++SS +    +   M      N   KL+Y TP+KI+ SK     +EKAY    L R+ +DE+HCCS+  HDFR DYK L  LK  +PN P++GLTATA   V+ D +  L +    L    ++NR N+FYEV+   +  ++   +I KLI SR+ GQSGI++CF+QKD E++T  L   GI A +Y+  +    K  +H KW     +++VAT AFGMGIDKP+VRFVIH SMSKS+ENYYQESGRA        CI  W+     ++ S +  E  G   L  M  Y      C+RV ++   DE +    C  MC  C       +S + AD+      I+K +E+    + K+T  K++     +     A L  R PG+         +++   HL+L  +L+ D+SF +++  +Y+  G K   L+S++  I +P+R
Sbjct:    1 VEIQLQELLERQQELIQRKRLLNKKIQRLSEDSGPGTSAGGGDSAENWQKEDFLWSQKIRDALCNSFQLRSFRSLQLETINATMAGRDVFLIMPTGGGKSLCYQLPAVCSDGFTLVICPLVSLMEDQLMVLDRLGVSATSLNASSSKEHVKWVHGEMTNK---NSRLKLLYVTPEKIAKSKLFMSRLEKAYQAGLLARVAVDEVHCCSQWGHDFRPDYKTLGILKRQFPNSPLIGLTATATTHVLKDAQKILCVPKP-LTFTASFNRPNLFYEVRLKPSSSQDFIADIVKLINSRYRGQSGIIYCFSQKDSEHVTMSLQKLGIRAGTYHANMEPRDKTKVHTKWTANEIQIVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRA------VLCI-DWRPPSSLRLSSMVVMENVGQKKLYEMVGYCQSPDRCRRVLIAQHFDEVWDSAKCNKMCDNC-------NSWEKADITPYCRDIVKILEQANQMDEKLTPLKLMDAWVGKG---VAKL--RVPGVRPPQLPRPEIERIIAHLLLQQFLREDFSFTAYATISYIKRGPKVDLLRSDKYAICLPMR 561

[Close]

BLAST of ATP-dependent DNA helicase vs. Ensembl Xenopus
Match: blm (Bloom syndrome RecQ like helicase [Source:NCBI gene;Acc:100124311])

HSP 1 Score: 273.863 bits (699), Expect = 3.057e-79
Identity = 163/448 (36.38%), Postives = 242/448 (54.02%), Query Frame = 1

Query:  253 NFPWSSNIKKLLQDKFKIKNFKSLQLKTINATLDKLDCIFISSPGSGKSLCYQLASMIS-GFTLVIAPLGSLIQDQMIVSEKFGISCISLDSNSSVKIQNEIFKAM-ETDPVDNVTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRLVIDEIHCCSELSHDFRQDYKNLHGLKSLYPNLPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEVKFLSNEKKEGEEICKLIKSRFDGQSGIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNEN-CKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFWKLAEYFKIGSNIFTEKSG--------IPNLNIMNRYILDDCTCKRVSLSSILDE-KFTVNDCKNMCSVCADT---ESEMSSIDIADVYKSALTIIK 1551
            NFP S  + K+   KF +  F++ QL+ INA L   DC  +   G GKSLCYQL   +S G T+VI+PL SLI DQ+       I    L  + +      I+  + + DP+     KL+Y TP+K+  S +L   +E  Y  + L R VIDE HC S+  HDFR DYK L+ L+  + ++P++ LTATAN  V  DI   L +     +   ++NR N+ Y+V      K+   +  + IK      SGI++C ++ +C+ + + L   G+ A +Y+  L    +  + +KW+N++ C+VI AT AFGMGIDKP+VR+VIH S+ KS+E YYQESGRAGRDG+ S C+LF+  ++  +I   I  EK G          NL  M  Y  +   C+R+ L +   E  F  N CK    V  D      E  S ++ D  ++ +  ++
Sbjct:  381 NFPHSKEMMKIFHKKFGLHRFRTNQLEAINACLLGEDCFILMPTGGGKSLCYQLPGCVSPGVTIVISPLRSLIVDQVQKLTSLDIPATYLTGDKTDAEAASIYLQLSKKDPI----IKLLYVTPEKVCASTRLISTMENLYERQLLARFVIDEAHCVSQWGHDFRPDYKRLNMLRQKFQSVPMMALTATANPRVQKDILNQLKMTKP-QIFTMSFNRDNLKYDV-LPKKPKRVALDCVEWIKKYHPNDSGIIYCLSRHECDTMADTLQKGGLAALAYHAGLADSNRDYVQHKWINQDDCQVICATIAFGMGIDKPDVRYVIHASLPKSVEGYYQESGRAGRDGEISHCLLFYSYSDVTRIRRLIQMEKDGNSHTKQTHFNNLYSMVHYCENVVECRRMQLLAYFGENNFNPNFCKENTRVSCDNCLGRKEFKSRNVTDDVRNIVRFVQ 822

[Close]

BLAST of ATP-dependent DNA helicase vs. Ensembl Mouse
Match: Recql (RecQ protein-like [Source:MGI Symbol;Acc:MGI:103021])

HSP 1 Score: 412.149 bits (1058), Expect = 1.166e-134
Identity = 239/607 (39.37%), Postives = 352/607 (57.99%), Query Frame = 1

Query:  130 AIDNEIKTLTHEKEDLIKKKKQLSISTKGHSI-----------TSNKDYGKENFPWSSNIKKLLQDKFKIKNFKSLQLKTINATLDKLDCIFISSPGSGKSLCYQLASMIS-GFTLVIAPLGSLIQDQMIVSEKFGISCISLDSNSSVKIQNEIFKAMETDPVD-NVTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRLVIDEIHCCSELSHDFRQDYKNLHGLKSLYPNLPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEVKFLSNEKKE-GEEICKLIKSRFDGQSGIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNENCKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFWKLAEYFKIGSNIFTEKSGIPNLNIMNRYILDDCTCKRVSLSSILDEKFTVNDCKNMC-SVCADTESEMSSIDIADVYKSALTIIKNIEKTKNPKITGKKIISELANQMS--LYFAD-LANRFPGIDYKLFLDKAFCHLVLVGYLKLDYSFGSFSNFTYVIAGSKT-LKSNEKIDIPIRIAKSDK--MRNLVQNVKQNESSNVK 1887
            AID +I+ LT  +++L+++K  L+   K +             TS   + KE+FPW   +K +LQ+ FK++ F+ LQL+TIN T+ + D   +   G GKSLCYQL ++ S GFTLVI PL SL++DQ++V ++ GIS   L+++SS     E  K +  + V+ N   KLIY TP+KI+ SK     +EKAY   RL    +DE+HCCS+  HDFR DYK L  LK  +PN  ++GLTATA N V+ D++  L +   CL    ++NR N+FYEV+   +  ++  E+I KLI  R+ GQSGI++CF+QKD E +T  L   GI A +Y+  +  + K  +H +W     +V+VAT AFGMGIDKP+VRFVIH SMSKS+ENYYQESGRAGRD  R+DCIL++   + F+I S +  E  G   L  M  Y  +   C+RV ++   DE +  + C  MC + C D   E    ++    +  + I+K  E   N K+T  K+I     + +  L  A  +A   P  D    L++   H +L  YLK DYSF +++  +Y+  G +  L SNE   + +++ KS +  +R  +   +Q E  + K
Sbjct:   20 AIDIQIQELTERRQELLQRKSVLTGKIKQYLEDSSAEASSDLDTSPAAWNKEDFPWFGKVKDVLQNVFKLQKFRPLQLETINVTMARKDIFLVMPTGGGKSLCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATMLNASSS----KEHVKWVHAEMVNKNSQLKLIYVTPEKIAKSKMFMSRLEKAYEAGRLTGAAVDEVHCCSQWGHDFRPDYKALGILKRQFPNASLMGLTATATNHVLKDVQKILCVGK-CLTFTASFNRPNLFYEVRQKPSSAEDFTEDIVKLINGRYKGQSGIIYCFSQKDSEQITISLQKLGIHAGTYHANMEPEDKTKVHTQWSANELQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDSRADCILYYGFGDIFRISSMVVMENVGQQKLYEMVSYCQNVSKCRRVLIAQHFDEVWNADACNKMCDNCCKDVSFEKK--NVTQHCRDLIKILKQAEGL-NEKLTPLKLIDAWMGKGAAKLRVAGVVAPALPRED----LERIVAHALLQQYLKEDYSFTAYATISYLKVGPRACLLSNEAHAVTMQVKKSAQSSVRGALSEARQVEQVDSK 614

[Close]

BLAST of ATP-dependent DNA helicase vs. Ensembl Mouse
Match: Recql (RecQ protein-like [Source:MGI Symbol;Acc:MGI:103021])

HSP 1 Score: 411.764 bits (1057), Expect = 1.631e-134
Identity = 239/607 (39.37%), Postives = 352/607 (57.99%), Query Frame = 1

Query:  130 AIDNEIKTLTHEKEDLIKKKKQLSISTKGHSI-----------TSNKDYGKENFPWSSNIKKLLQDKFKIKNFKSLQLKTINATLDKLDCIFISSPGSGKSLCYQLASMIS-GFTLVIAPLGSLIQDQMIVSEKFGISCISLDSNSSVKIQNEIFKAMETDPVD-NVTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRLVIDEIHCCSELSHDFRQDYKNLHGLKSLYPNLPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEVKFLSNEKKE-GEEICKLIKSRFDGQSGIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNENCKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFWKLAEYFKIGSNIFTEKSGIPNLNIMNRYILDDCTCKRVSLSSILDEKFTVNDCKNMC-SVCADTESEMSSIDIADVYKSALTIIKNIEKTKNPKITGKKIISELANQMS--LYFAD-LANRFPGIDYKLFLDKAFCHLVLVGYLKLDYSFGSFSNFTYVIAGSKT-LKSNEKIDIPIRIAKSDK--MRNLVQNVKQNESSNVK 1887
            AID +I+ LT  +++L+++K  L+   K +             TS   + KE+FPW   +K +LQ+ FK++ F+ LQL+TIN T+ + D   +   G GKSLCYQL ++ S GFTLVI PL SL++DQ++V ++ GIS   L+++SS     E  K +  + V+ N   KLIY TP+KI+ SK     +EKAY   RL    +DE+HCCS+  HDFR DYK L  LK  +PN  ++GLTATA N V+ D++  L +   CL    ++NR N+FYEV+   +  ++  E+I KLI  R+ GQSGI++CF+QKD E +T  L   GI A +Y+  +  + K  +H +W     +V+VAT AFGMGIDKP+VRFVIH SMSKS+ENYYQESGRAGRD  R+DCIL++   + F+I S +  E  G   L  M  Y  +   C+RV ++   DE +  + C  MC + C D   E    ++    +  + I+K  E   N K+T  K+I     + +  L  A  +A   P  D    L++   H +L  YLK DYSF +++  +Y+  G +  L SNE   + +++ KS +  +R  +   +Q E  + K
Sbjct:   20 AIDIQIQELTERRQELLQRKSVLTGKIKQYLEDSSAEASSDLDTSPAAWNKEDFPWFGKVKDVLQNVFKLQKFRPLQLETINVTMARKDIFLVMPTGGGKSLCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATMLNASSS----KEHVKWVHAEMVNKNSQLKLIYVTPEKIAKSKMFMSRLEKAYEAGRLTGAAVDEVHCCSQWGHDFRPDYKALGILKRQFPNASLMGLTATATNHVLKDVQKILCVGK-CLTFTASFNRPNLFYEVRQKPSSAEDFTEDIVKLINGRYKGQSGIIYCFSQKDSEQITISLQKLGIHAGTYHANMEPEDKTKVHTQWSANELQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDSRADCILYYGFGDIFRISSMVVMENVGQQKLYEMVSYCQNVSKCRRVLIAQHFDEVWNADACNKMCDNCCKDVSFEKK--NVTQHCRDLIKILKQAEGL-NEKLTPLKLIDAWMGKGAAKLRVAGVVAPALPRED----LERIVAHALLQQYLKEDYSFTAYATISYLKVGPRACLLSNEAHAVTMQVKKSAQSSVRGALSEARQVEQVDSK 614

[Close]

BLAST of ATP-dependent DNA helicase vs. Ensembl Mouse
Match: Recql (RecQ protein-like [Source:MGI Symbol;Acc:MGI:103021])

HSP 1 Score: 412.149 bits (1058), Expect = 1.732e-134
Identity = 239/607 (39.37%), Postives = 352/607 (57.99%), Query Frame = 1

Query:  130 AIDNEIKTLTHEKEDLIKKKKQLSISTKGHSI-----------TSNKDYGKENFPWSSNIKKLLQDKFKIKNFKSLQLKTINATLDKLDCIFISSPGSGKSLCYQLASMIS-GFTLVIAPLGSLIQDQMIVSEKFGISCISLDSNSSVKIQNEIFKAMETDPVD-NVTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRLVIDEIHCCSELSHDFRQDYKNLHGLKSLYPNLPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEVKFLSNEKKE-GEEICKLIKSRFDGQSGIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNENCKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFWKLAEYFKIGSNIFTEKSGIPNLNIMNRYILDDCTCKRVSLSSILDEKFTVNDCKNMC-SVCADTESEMSSIDIADVYKSALTIIKNIEKTKNPKITGKKIISELANQMS--LYFAD-LANRFPGIDYKLFLDKAFCHLVLVGYLKLDYSFGSFSNFTYVIAGSKT-LKSNEKIDIPIRIAKSDK--MRNLVQNVKQNESSNVK 1887
            AID +I+ LT  +++L+++K  L+   K +             TS   + KE+FPW   +K +LQ+ FK++ F+ LQL+TIN T+ + D   +   G GKSLCYQL ++ S GFTLVI PL SL++DQ++V ++ GIS   L+++SS     E  K +  + V+ N   KLIY TP+KI+ SK     +EKAY   RL    +DE+HCCS+  HDFR DYK L  LK  +PN  ++GLTATA N V+ D++  L +   CL    ++NR N+FYEV+   +  ++  E+I KLI  R+ GQSGI++CF+QKD E +T  L   GI A +Y+  +  + K  +H +W     +V+VAT AFGMGIDKP+VRFVIH SMSKS+ENYYQESGRAGRD  R+DCIL++   + F+I S +  E  G   L  M  Y  +   C+RV ++   DE +  + C  MC + C D   E    ++    +  + I+K  E   N K+T  K+I     + +  L  A  +A   P  D    L++   H +L  YLK DYSF +++  +Y+  G +  L SNE   + +++ KS +  +R  +   +Q E  + K
Sbjct:   20 AIDIQIQELTERRQELLQRKSVLTGKIKQYLEDSSAEASSDLDTSPAAWNKEDFPWFGKVKDVLQNVFKLQKFRPLQLETINVTMARKDIFLVMPTGGGKSLCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATMLNASSS----KEHVKWVHAEMVNKNSQLKLIYVTPEKIAKSKMFMSRLEKAYEAGRLTGAAVDEVHCCSQWGHDFRPDYKALGILKRQFPNASLMGLTATATNHVLKDVQKILCVGK-CLTFTASFNRPNLFYEVRQKPSSAEDFTEDIVKLINGRYKGQSGIIYCFSQKDSEQITISLQKLGIHAGTYHANMEPEDKTKVHTQWSANELQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDSRADCILYYGFGDIFRISSMVVMENVGQQKLYEMVSYCQNVSKCRRVLIAQHFDEVWNADACNKMCDNCCKDVSFEKK--NVTQHCRDLIKILKQAEGL-NEKLTPLKLIDAWMGKGAAKLRVAGVVAPALPRED----LERIVAHALLQQYLKEDYSFTAYATISYLKVGPRACLLSNEAHAVTMQVKKSAQSSVRGALSEARQVEQVDSK 614

[Close]

BLAST of ATP-dependent DNA helicase vs. Ensembl Mouse
Match: Blm (Bloom syndrome, RecQ like helicase [Source:MGI Symbol;Acc:MGI:1328362])

HSP 1 Score: 296.975 bits (759), Expect = 7.880e-86
Identity = 171/449 (38.08%), Postives = 249/449 (55.46%), Query Frame = 1

Query:  253 NFPWSSNIKKLLQDKFKIKNFKSLQLKTINATLDKLDCIFISSPGSGKSLCYQLASMIS-GFTLVIAPLGSLIQDQMIVSEKFGISCISLDSN-SSVKIQNEIFKAMETDPVDNVTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRLVIDEIHCCSELSHDFRQDYKNLHGLKSLYPNLPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEVKFLSNEKKEGEEICKLIKSRFDGQSGIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNE-NCKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFWKLAEYFKIGSNIFTEKSG--------IPNLNIMNRYILDDCTCKRVSLSSILDEK-FTVNDCKNMCSVCADTESEMSSIDIADVYKSALTIIKNIEK 1563
            NFP +  + K+   KF + NF++ QL+ INA L   DC  +   G GKSLCYQL + +S G T+VI+PL SLI DQ+     F I    L  + +  +  N   +  + DP+     KL+Y TP+K+  S +L   +E  Y  K L R VIDE HC S+  HDFRQDYK ++ L+  +P++PV+ LTATAN  V  DI T L +     V   ++NR N+ Y V      KK   +  + I+      SGI++C ++++C+ + + L   G+ A +Y+  L    + ++ +KW+N+ NC+VI AT AFGMGIDKP+VRFVIH S+ KS+E YYQESGRAGRDG+ S C+LF+   +  ++   I  EK G        + NL  M  Y  +   C+R+ L +   EK F  + CK    V  D   +       DV      II+ +++
Sbjct:  659 NFPHTKEMMKIFHKKFGLHNFRTNQLEAINAALLGEDCFILMPTGGGKSLCYQLPACVSPGVTIVISPLRSLIVDQVQKLTSFDIPATYLTGDKTDSEAANIYLQLSKKDPI----IKLLYVTPEKVCASNRLISTLENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPSVPVMALTATANPRVQKDILTQLKILRP-QVFSMSFNRHNLKYYV-LPKKPKKVAFDCLEWIRKHHPYDSGIIYCLSRRECDTMADTLQREGLAALAYHAGLSDSARDEVQHKWINQDNCQVICATIAFGMGIDKPDVRFVIHASLPKSMEGYYQESGRAGRDGEISHCVLFYTYHDVTRLKRLIMMEKDGNYHTKETHVNNLYSMVHYCENITECRRIQLLAYFGEKGFNPDFCKKYPDVSCDNCCKTKDYKTKDVTDDVKNIIRFVQE 1101

[Close]

BLAST of ATP-dependent DNA helicase vs. Ensembl Mouse
Match: Blm (Bloom syndrome, RecQ like helicase [Source:MGI Symbol;Acc:MGI:1328362])

HSP 1 Score: 296.59 bits (758), Expect = 8.571e-86
Identity = 171/449 (38.08%), Postives = 249/449 (55.46%), Query Frame = 1

Query:  253 NFPWSSNIKKLLQDKFKIKNFKSLQLKTINATLDKLDCIFISSPGSGKSLCYQLASMIS-GFTLVIAPLGSLIQDQMIVSEKFGISCISLDSN-SSVKIQNEIFKAMETDPVDNVTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRLVIDEIHCCSELSHDFRQDYKNLHGLKSLYPNLPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEVKFLSNEKKEGEEICKLIKSRFDGQSGIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNE-NCKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFWKLAEYFKIGSNIFTEKSG--------IPNLNIMNRYILDDCTCKRVSLSSILDEK-FTVNDCKNMCSVCADTESEMSSIDIADVYKSALTIIKNIEK 1563
            NFP +  + K+   KF + NF++ QL+ INA L   DC  +   G GKSLCYQL + +S G T+VI+PL SLI DQ+     F I    L  + +  +  N   +  + DP+     KL+Y TP+K+  S +L   +E  Y  K L R VIDE HC S+  HDFRQDYK ++ L+  +P++PV+ LTATAN  V  DI T L +     V   ++NR N+ Y V      KK   +  + I+      SGI++C ++++C+ + + L   G+ A +Y+  L    + ++ +KW+N+ NC+VI AT AFGMGIDKP+VRFVIH S+ KS+E YYQESGRAGRDG+ S C+LF+   +  ++   I  EK G        + NL  M  Y  +   C+R+ L +   EK F  + CK    V  D   +       DV      II+ +++
Sbjct:  656 NFPHTKEMMKIFHKKFGLHNFRTNQLEAINAALLGEDCFILMPTGGGKSLCYQLPACVSPGVTIVISPLRSLIVDQVQKLTSFDIPATYLTGDKTDSEAANIYLQLSKKDPI----IKLLYVTPEKVCASNRLISTLENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPSVPVMALTATANPRVQKDILTQLKILRP-QVFSMSFNRHNLKYYV-LPKKPKKVAFDCLEWIRKHHPYDSGIIYCLSRRECDTMADTLQREGLAALAYHAGLSDSARDEVQHKWINQDNCQVICATIAFGMGIDKPDVRFVIHASLPKSMEGYYQESGRAGRDGEISHCVLFYTYHDVTRLKRLIMMEKDGNYHTKETHVNNLYSMVHYCENITECRRIQLLAYFGEKGFNPDFCKKYPDVSCDNCCKTKDYKTKDVTDDVKNIIRFVQE 1098

[Close]

BLAST of ATP-dependent DNA helicase vs. UniProt/SwissProt
Match: sp|Q6AYJ1|RECQ1_RAT (ATP-dependent DNA helicase Q1 OS=Rattus norvegicus OX=10116 GN=Recql PE=1 SV=1)

HSP 1 Score: 413.305 bits (1061), Expect = 1.706e-134
Identity = 228/590 (38.64%), Postives = 346/590 (58.64%), Query Frame = 1

Query:  112 IDKRIVAIDNEIKTLTHEKEDLIKKKKQLSISTK-----------GHSITSNKDYGKENFPWSSNIKKLLQDKFKIKNFKSLQLKTINATLDKLDCIFISSPGSGKSLCYQLASMIS-GFTLVIAPLGSLIQDQMIVSEKFGISCISLDSNSSVKIQNEIFKAMETDPVD-NVTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRLVIDEIHCCSELSHDFRQDYKNLHGLKSLYPNLPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEVKFLSNEKKEG-EEICKLIKSRFDGQSGIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNENCKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFWKLAEYFKIGSNIFTEKSGIPNLNIMNRYILDDCTCKRVSLSSILDEKFTVNDCKNMCSVCADTESEMSSIDIADVYKSALTIIKNIEKTKNPKITGKKIISELANQMSLYFADLANRFPGIDYKLFLDKAFCHLVLVGYLKLDYSFGSFSNFTYVIAGSK-TLKSNEKIDIPIRIAKSDK 1836
            +   + A+D +I+ LT  + +L+++K  L+   K           G   TS   + KE+FPWS  +K +L+D FK++ F+ LQL+T+NAT+ + D   +   G GKSLCYQL ++ S GFTLVI PL SL++DQ++V ++ GIS   L+S+SS     E  K + T+ ++ N   KLIY TP+KI+ SK     +EKAY   RL  + +DE+HCCS+  HDFR DYK L  LK  +PN+ ++GLTATA N V+ D +  L +   CL    ++NR N++YEV+   +  ++  E I  LI  R+ G+SGI++CF+QKD E +T  L   G+ A +Y+  +  + +  +H +W     +V+VAT AFGMGIDKP+VRFVIH SMSKS+ENYYQESGRAGRD  R+DCIL++   + F+I S +  E  G   L  M  Y  +   C+R  ++   DE +  + C  MC  C   +S     +I +  ++ + I+K  E   N K+T  K+I     + +  F       P +  +  L+K   H +L  YLK DYSF +++  +Y+  G + +L SNE   + +++ +S +
Sbjct:   14 VSSELHAVDIQIQELTERQHELLQRKSVLTKRIKQCLEDSAAEASGDCDTSPAAWSKEDFPWSGKVKHVLRDVFKLQKFRPLQLETVNATMARKDIFLVMPTGGGKSLCYQLPALCSDGFTLVICPLISLMEDQLMVLQQLGISATMLNSSSS----KEHVKCVHTEMMNKNSHLKLIYVTPEKIAKSKMFMSRLEKAYEAGRLTGVAVDEVHCCSQWGHDFRPDYKALGILKRQFPNISLIGLTATATNHVLKDAQKILCVEK-CLTFTASFNRPNLYYEVRQKPSSAEDFIENIANLINGRYKGKSGIIYCFSQKDSEQVTISLQKLGVRAGTYHANMEPEDRTKVHTQWSANELQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDWRADCILYYGFGDIFRISSMVVMENVGQQKLYEMVSYCQNISKCRRALIAQHFDEVWNADACNKMCDNCCKDDS-FEKKNITEHCQALIKILKQAEGL-NEKLTPLKLIDAWMGKGAAKFRVAGVAVPALP-REDLEKIIVHALLQQYLKEDYSFTAYATISYLKVGPRASLLSNEGHAVTMQVKRSTQ 595

[Close]

BLAST of ATP-dependent DNA helicase vs. UniProt/SwissProt
Match: sp|Q9Z129|RECQ1_MOUSE (ATP-dependent DNA helicase Q1 OS=Mus musculus OX=10090 GN=Recql PE=1 SV=2)

HSP 1 Score: 412.149 bits (1058), Expect = 1.211e-133
Identity = 239/607 (39.37%), Postives = 352/607 (57.99%), Query Frame = 1

Query:  130 AIDNEIKTLTHEKEDLIKKKKQLSISTKGHSI-----------TSNKDYGKENFPWSSNIKKLLQDKFKIKNFKSLQLKTINATLDKLDCIFISSPGSGKSLCYQLASMIS-GFTLVIAPLGSLIQDQMIVSEKFGISCISLDSNSSVKIQNEIFKAMETDPVD-NVTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRLVIDEIHCCSELSHDFRQDYKNLHGLKSLYPNLPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEVKFLSNEKKE-GEEICKLIKSRFDGQSGIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNENCKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFWKLAEYFKIGSNIFTEKSGIPNLNIMNRYILDDCTCKRVSLSSILDEKFTVNDCKNMC-SVCADTESEMSSIDIADVYKSALTIIKNIEKTKNPKITGKKIISELANQMS--LYFAD-LANRFPGIDYKLFLDKAFCHLVLVGYLKLDYSFGSFSNFTYVIAGSKT-LKSNEKIDIPIRIAKSDK--MRNLVQNVKQNESSNVK 1887
            AID +I+ LT  +++L+++K  L+   K +             TS   + KE+FPW   +K +LQ+ FK++ F+ LQL+TIN T+ + D   +   G GKSLCYQL ++ S GFTLVI PL SL++DQ++V ++ GIS   L+++SS     E  K +  + V+ N   KLIY TP+KI+ SK     +EKAY   RL    +DE+HCCS+  HDFR DYK L  LK  +PN  ++GLTATA N V+ D++  L +   CL    ++NR N+FYEV+   +  ++  E+I KLI  R+ GQSGI++CF+QKD E +T  L   GI A +Y+  +  + K  +H +W     +V+VAT AFGMGIDKP+VRFVIH SMSKS+ENYYQESGRAGRD  R+DCIL++   + F+I S +  E  G   L  M  Y  +   C+RV ++   DE +  + C  MC + C D   E    ++    +  + I+K  E   N K+T  K+I     + +  L  A  +A   P  D    L++   H +L  YLK DYSF +++  +Y+  G +  L SNE   + +++ KS +  +R  +   +Q E  + K
Sbjct:   20 AIDIQIQELTERRQELLQRKSVLTGKIKQYLEDSSAEASSDLDTSPAAWNKEDFPWFGKVKDVLQNVFKLQKFRPLQLETINVTMARKDIFLVMPTGGGKSLCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATMLNASSS----KEHVKWVHAEMVNKNSQLKLIYVTPEKIAKSKMFMSRLEKAYEAGRLTGAAVDEVHCCSQWGHDFRPDYKALGILKRQFPNASLMGLTATATNHVLKDVQKILCVGK-CLTFTASFNRPNLFYEVRQKPSSAEDFTEDIVKLINGRYKGQSGIIYCFSQKDSEQITISLQKLGIHAGTYHANMEPEDKTKVHTQWSANELQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDSRADCILYYGFGDIFRISSMVVMENVGQQKLYEMVSYCQNVSKCRRVLIAQHFDEVWNADACNKMCDNCCKDVSFEKK--NVTQHCRDLIKILKQAEGL-NEKLTPLKLIDAWMGKGAAKLRVAGVVAPALPRED----LERIVAHALLQQYLKEDYSFTAYATISYLKVGPRACLLSNEAHAVTMQVKKSAQSSVRGALSEARQVEQVDSK 614

[Close]

BLAST of ATP-dependent DNA helicase vs. UniProt/SwissProt
Match: sp|P46063|RECQ1_HUMAN (ATP-dependent DNA helicase Q1 OS=Homo sapiens OX=9606 GN=RECQL PE=1 SV=3)

HSP 1 Score: 408.683 bits (1049), Expect = 2.299e-132
Identity = 246/609 (40.39%), Postives = 353/609 (57.96%), Query Frame = 1

Query:  112 IDKRIVAIDNEIKTLTHEKEDLIKKKKQ--------LSISTKGHS---ITSNKDYGKENFPWSSNIKKLLQDKFKIKNFKSLQLKTINATLDKLDCIFISSPGSGKSLCYQLASMIS-GFTLVIAPLGSLIQDQMIVSEKFGISCISLDSNSSVKIQNEIFKAMETDPVD-NVTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRLVIDEIHCCSELSHDFRQDYKNLHGLKSLYPNLPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEVKF-LSNEKKEGEEICKLIKSRFDGQSGIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNENCKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFWKLAEYFKIGSNIFTEKSGIPNLNIMNRYILDDCTCKRVSLSSILDEKFTVNDCKNMCSVCADTESEMSSIDIADVYKSALTIIKNIEKTKNPKITGKKIISELANQMS--LYFAD-LANRFPGIDYKLFLDKAFCHLVLVGYLKLDYSFGSFSNFTYVIAGSKT-LKSNEKIDIPIRIAKSDKMRNLVQNVKQNESSNV 1884
            I   + A++ +I+ LT  +++LI+KKK         L  S  G S    +S   + KE+FPWS  +K +LQ+ FK++ F+ LQL+TIN T+   +   +   G GKSLCYQL ++ S GFTLVI PL SL++DQ++V ++ GIS   L+++SS     E  K +  + V+ N   KLIY TP+KI+ SK     +EKAY  +R  R+ +DE+HCCS+  HDFR DYK L  LK  +PN  ++GLTATA N V+ D +  L +   C     ++NR N++YEV+   SN +   E+I KLI  R+ GQSGI++CF+QKD E +T  L N GI A +Y+  L  + K  +H KW     +V+VAT AFGMGIDKP+VRFVIH SMSKS+ENYYQESGRAGRD  ++DCIL++   + F+I S +  E  G   L  M  Y  +   C+RV ++   DE +    C  MC  C   +S     +I +  +  + I+K  E+  N K+T  K+I     + +  L  A  +A   P  D    L+K   H ++  YLK DYSF +++  +Y+  G K  L +NE   I +++ KS       QN  + ESS  
Sbjct:   14 ITSELHAVEIQIQELTERQQELIQKKKVLTKKIKQCLEDSDAGASNEYDSSPAAWNKEDFPWSGKVKDILQNVFKLEKFRPLQLETINVTMAGKEVFLVMPTGGGKSLCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATMLNASSS----KEHVKWVHAEMVNKNSELKLIYVTPEKIAKSKMFMSRLEKAYEARRFTRIAVDEVHCCSQWGHDFRPDYKALGILKRQFPNASLIGLTATATNHVLTDAQKILCIEK-CFTFTASFNRPNLYYEVRQKPSNTEDFIEDIVKLINGRYKGQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKWSANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKADCILYYGFGDIFRISSMVVMENVGQQKLYEMVSYCQNISKCRRVLMAQHFDEVWNSEACNKMCDNCCK-DSAFERKNITEYCRDLIKILKQAEEL-NEKLTPLKLIDSWMGKGAAKLRVAGVVAPTLPRED----LEKIIAHFLIQQYLKEDYSFTAYATISYLKIGPKANLLNNEAHAITMQVTKS------TQNSFRAESSQT 605

[Close]

BLAST of ATP-dependent DNA helicase vs. UniProt/SwissProt
Match: sp|Q5RF63|RECQ1_PONAB (ATP-dependent DNA helicase Q1 OS=Pongo abelii OX=9601 GN=RECQL PE=2 SV=1)

HSP 1 Score: 406.371 bits (1043), Expect = 1.855e-131
Identity = 240/593 (40.47%), Postives = 347/593 (58.52%), Query Frame = 1

Query:  112 IDKRIVAIDNEIKTLTHEKEDLIKKKKQ--------LSISTKGHS---ITSNKDYGKENFPWSSNIKKLLQDKFKIKNFKSLQLKTINATLDKLDCIFISSPGSGKSLCYQLASMIS-GFTLVIAPLGSLIQDQMIVSEKFGISCISLDSNSSVKIQNEIFKAMETDPVD-NVTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRLVIDEIHCCSELSHDFRQDYKNLHGLKSLYPNLPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEVKF-LSNEKKEGEEICKLIKSRFDGQSGIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNENCKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFWKLAEYFKIGSNIFTEKSGIPNLNIMNRYILDDCTCKRVSLSSILDEKFTVNDCKNMCSVCADTESEMSSIDIADVYKSALTIIKNIEKTKNPKITGKKIISELANQMS--LYFAD-LANRFPGIDYKLFLDKAFCHLVLVGYLKLDYSFGSFSNFTYVIAGSKT-LKSNEKIDIPIRIAKSDK 1836
            I   + A++ +I+ LT  +E+LI+KKK         L  S  G S    +S   + KE+FPWS  +K +LQ+ FK++ F+ LQL+TIN T+   +   +   G GK LCYQL ++ S GFTLVI PL SL++DQ++V ++ GIS   L+++SS     E  K +  + V+ N   KLIY TP+KI+ SK     +EKAY  +R  R+ +DE+HCCS+  HDFR DYK L  LK  +PN  ++GLTATA N V+ D +  L +   C     ++NR N++YEV+   SN +   E+I KLI  R+ GQSGI++CF+QKD E +T  L N GI A +Y+  L  + K  +H KW     +V+VAT AFGMGIDKP+VRFVIH SMSKS+ENYYQESGRAGRD  ++DCIL++   + F+I S +  E  G   L  M  Y  +   C+R+ ++   DE +    C  MC  C   +S     +I +  +  + I+K  E+  N K+T  K+I     + +  L  A  +A   P  D    L+K   H ++  YLK DYSF +++  +Y+  G K  L +NE   I +++ KS +
Sbjct:   14 ITSELHAVEIQIQELTERQEELIQKKKVLTKKIKQCLEDSDAGASNEYDSSPAAWNKEDFPWSGKVKDVLQNVFKLQKFRPLQLETINVTMAGKEVFLVMPTGGGKGLCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATMLNASSS----KEHVKWVHAEMVNKNSELKLIYVTPEKIAKSKMFMSRLEKAYEARRFTRIAVDEVHCCSQWGHDFRPDYKALGILKRQFPNASLIGLTATATNHVLTDAQKILCIEK-CFTFTASFNRPNLYYEVRQKPSNTEDFIEDIVKLINGRYKGQSGIIYCFSQKDSEQVTVSLRNLGIHAGAYHANLEPEDKTTVHRKWSANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKADCILYYGFGDIFRISSMVVMENVGQQKLYEMVSYCQNISKCRRLLMAQHFDEVWNSEACNKMCDNCCK-DSAFERKNITEYCRDLIKILKQAEEL-NEKLTPLKLIDSWMGKGAAKLRVAGVVAPTLPRED----LEKIIAHFLIQQYLKEDYSFTAYATISYLKIGPKANLLNNEAHAITMQVTKSTQ 595

[Close]

BLAST of ATP-dependent DNA helicase vs. UniProt/SwissProt
Match: sp|Q9TXJ8|RECQ1_CAEEL (Putative ATP-dependent DNA helicase Q1 OS=Caenorhabditis elegans OX=6239 GN=K02F3.12 PE=3 SV=3)

HSP 1 Score: 402.134 bits (1032), Expect = 5.877e-130
Identity = 230/610 (37.70%), Postives = 357/610 (58.52%), Query Frame = 1

Query:  109 EIDKRIVAIDNEIKTLTHEKEDLIKKK----KQLSISTKGHSITSNKDYGKENFPWSSNIKKLLQDKFKIKNFKSLQLKTINATLDKLDCIFISSPGSGKSLCYQLASMIS-GFTLVIAPLGSLIQDQMIVSEKFGISCISLDSNSSVKIQNEIFKAMETDPVDN--VTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRLVIDEIHCCSELSHDFRQDYKNLHGLKSLYPNLPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEV-KFLSNEKKEGEEICKLIKSRFDGQSGIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNENCKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFWKLAEYFKIGSNIFTEKSGIPNLNIMNRYILDDCTCKRVSLSSILDEKFTVNDCKNMCSVCAD-----TESEMSSIDIADVYKSALTIIK---NIEKTKNPKITGKKIISELANQMSLYFADLANRFPGIDYKLFLDKAFCHLVLVGYLKLDYSFGSFSNFTYVIAGSKTLKSNEKIDIPIRIAKSDKMRNLVQNVKQNESSNVKK 1890
            ++D  I  ID +I  L  +K +L +K+    +++ + T   S      + ++ FPWS    K+L+++F ++ F+ LQ   INA + K D + I S G GKSLCYQL ++++ G  LV++PL SL++DQ++     GI   SL++N+S     E  K +E D + N    ++L+Y TP+K++ SKK+   +EK+     L  + IDE+HCCS+  HDFR DY  L+ LK  +  +P+LGLTATA ++V++D+K  L + +  L  +  +NRSN+ Y+V +   +E +  EEI K IK  F GQ+GI++C ++ DCE +   L ++GI A  Y+  +    +   H  W++   +VIVAT AFGMGIDKPNVRFVIH S+ KS+ENYYQESGRAGRDG+ + CIL+++LA+ FK  S +  E++GI NL  M RY  D  TC+RV L+   +E +  + C+  C  C +       S   S D+++  K+ + II+   N  K  + +ITG K++ EL          L  +  G   + F +K   +L+L GYL+ D+ +  +S  +YV+ GSK    N K  I +R  +  K R      K+  SS+V++
Sbjct:   38 DLDGEIGQIDQQISQLRRKKSELTQKRQAIERKIELKTNEDSDVVTDRWDRDGFPWSDEATKILKEQFHLEKFRPLQRAAINAVMSKEDAVVILSTGGGKSLCYQLPALLANGLALVVSPLISLVEDQILQLRSLGIDSSSLNANTS----KEEAKRVE-DAITNKDSKFRLLYVTPEKLAKSKKMMNKLEKSLSVGFLKLIAIDEVHCCSQWGHDFRTDYSFLNVLKRQFKGVPILGLTATATSNVLDDVKDMLGIQA-ALTFRAGFNRSNLKYKVVQKPGSEDECTEEIAKTIKRDFAGQTGIIYCLSRNDCEKVAKALKSHGIKAKHYHAYMEPVDRSGAHQGWISGKIQVIVATVAFGMGIDKPNVRFVIHHSLPKSIENYYQESGRAGRDGQPATCILYYRLADIFKQSSMVQQERTGIQNLYNMVRYAADSSTCRRVKLAEHFEEAWEPSWCQKQCDTCENGNGFVGTSSKESTDVSEAAKTTVRIIEEHLNSAKDGSGRITGNKLV-EL----------LTKKLKGSRNREFCEKLIVNLLLEGYLQEDFHYTVYSVISYVVIGSKWRVYNGKDAIKMRHVEESKSR------KRKASSSVEE 624

[Close]

BLAST of ATP-dependent DNA helicase vs. TrEMBL
Match: E9G2Y5 (ATP-dependent DNA helicase OS=Daphnia pulex OX=6669 GN=RecQ1 PE=3 SV=1)

HSP 1 Score: 420.624 bits (1080), Expect = 9.329e-135
Identity = 221/583 (37.91%), Postives = 355/583 (60.89%), Query Frame = 1

Query:  112 IDKRIVAIDNEIKTLTHEKEDLIKKKKQLSISTKGHSIT--SNKDYGKENFPWSSNIKKLLQDKFKIKNFKSLQLKTINATLDKLDCIFISSPGSGKSLCYQLASMIS-GFTLVIAPLGSLIQDQMIVSEKFGISCISLDSNSSVKIQNEIFKAMETDPVDNVTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRLVIDEIHCCSELSHDFRQDYKNLHGLKSLYPNLPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEVKFLSNEKKEG-EEICKLIKSRFDGQSGIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNENCKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFWKLAEYFKIGSNIFTEKSGIPNLNIMNRYILDDCTCKRVSLSSILDEKFTVNDCKNMCSVCADTESEMSSIDIADVYKSALTIIKNIEKTKNPKITGKKIISELAN--QMSLYFADL--ANRFPGIDYKLFLDKAFCHLVLVGYLKLDYSFGSFSNFTYVIAGSKTLKSNEKIDIPIRIAKSDK 1836
            ID  +  ++ +I  L   K  L+K+K+ L       +    +++D+   +FPW+  + + L+D F I+ F+ +QL  +NATL   D I I   G GKSLCYQL +++S G TLVI PL SL++DQ+   EK GI    L+++SS +  N +  AM TD   ++  KL+Y TP+K++ SK+    ++K Y  KR   + +DE+HCCS+  HDFR DYK L  L+SL+P +P++GLTATA  +V ND++  LN+  + LV K ++NR N++YEV+   + +KE  +E+ +L+ +RF GQSGI++  + KDC+ L +EL       +SY+ +L    + ++H  W     + +VAT AFGMGIDKP+VRFVIH S+SKS+EN+YQESGRAGRD  ++ CI++W+L++ F++ + +FTE++G+ NL  M  Y LD   C+R  ++S  DE++  + C  MC  C+  +S  + I+I +   +   I++  E+ +  ++T +K+I    N  Q+SL   D   A + P    +  L     H +L GYLK D+ F  +S  +Y++ G +    N++I + +  +  D+
Sbjct:   13 IDAELRIVEEDIDKLQERKTTLLKRKQALKEKANEEATKKLASQDWESNDFPWTKKLYQTLKDAFHIEKFRPMQLSAMNATLKGHDVILIMPTGGGKSLCYQLPALVSDGITLVITPLVSLMEDQLASLEKLGIEAAKLNASSSKEEVNMVHLAM-TDAKSSL--KLLYVTPEKLAKSKRFMTKLQKMYQIKRFACVAVDEVHCCSQWGHDFRPDYKYLGVLRSLFPTVPIVGLTATATLNVTNDVQKMLNMK-NSLVFKASFNRPNLYYEVRIKPSTQKECIDELVQLLTNRFHGQSGIIYTTSVKDCDQLASELRQQKCRVASYHASLEPADRTEVHTGWRENRYQAVVATIAFGMGIDKPDVRFVIHHSISKSMENFYQESGRAGRDDLQACCIVYWRLSDLFRLSTMVFTEQTGLRNLYAMAAYCLDPERCRREIIASHFDERWESSSCNKMCDHCSK-DSTSAEINIVEHLTTLRQILERAEE-QQVRVTAQKLIDAWQNTGQVSLRLPDFKKAAKLPRDKCESIL----AHFLLEGYLKEDFHFTPYSTISYLLLGERAHFINKEITMKVEASSVDE 585

[Close]

BLAST of ATP-dependent DNA helicase vs. TrEMBL
Match: J3S495 (ATP-dependent DNA helicase OS=Crotalus adamanteus OX=8729 PE=2 SV=1)

HSP 1 Score: 419.468 bits (1077), Expect = 6.572e-134
Identity = 225/576 (39.06%), Postives = 341/576 (59.20%), Query Frame = 1

Query:  112 IDKRIVAIDNEIKTLTHEKEDLIKKKKQL--------------SISTKGHSI---TSNKDYGKENFPWSSNIKKLLQDKFKIKNFKSLQLKTINATLDKLDCIFISSPGSGKSLCYQLASMIS-GFTLVIAPLGSLIQDQMIVSEKFGISCISLDSNSSVKIQNEIFKAMETDPVDNVTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRLVIDEIHCCSELSHDFRQDYKNLHGLKSLYPNLPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEVKFLSNEKKEG-EEICKLIKSRFDGQSGIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNENCKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFWKLAEYFKIGSNIFTEKSGIPNLNIMNRYILDDCTCKRVSLSSILDEKFTVNDCKNMCSVCADTESEMSSIDIADVYKSALTIIKNIEKTKNPKITGKKIISELANQMS-LYFADLANRFPGIDYKLFLDKAFCHLVLVGYLKLDYSFGSFSNFTYVIAGSK 1779
            + + +V++DNE++ L  + ++L++ ++QL              S +  G S    ++ +D+ KE+FPWS+ I+ +LQ  F ++NF+ LQL+TINAT+   D   +   G GKSLCYQL +  S GFTLVI PL SL++DQ+++ E+ G+S   L+++SS +    +   M +    N   KL+Y TP+KI+ SK     +EKAY   +L R+ +DE+HCCS+  HDFR DYK L  LK  +PN P++GLTATA   V+ D +  L +   C++   ++NR N++YEV+   +  +   E+I KLI  R+ G SGI++CF+QKD E +T  L   GI A +Y+  +    K  +H +W     +V+VAT AFGMGIDKP+VRFVIH SMSKS+ENYYQESGRAGRD +R+DCIL++   + F+I + +  E  G   L  M  Y  D   C+RV ++   DE +    C  MC  C   E+ +  +D+A+  +  L I++ +++ K      K I + L   +S L     A R P    +  L++   HL+L  YLK D+SF +F+  +YV  G +
Sbjct:    8 LQEELVSVDNELQALEIQIQELLEHQQQLIQKKTVLKKKITHFSDTESGSSKETESATEDWNKEDFPWSTKIRDVLQKSFGLQNFRPLQLETINATMAGRDVFLVMPTGGGKSLCYQLPAEGSPGFTLVICPLISLMEDQLMMLEQLGVSATLLNASSSKEHVKWVHAEMLSR---NSQLKLLYVTPEKIAKSKMFMSKLEKAYQTGQLTRIAVDEVHCCSQWGHDFRPDYKLLGILKRQFPNAPLIGLTATATGHVLRDAQNILCV-PKCIIFTASFNRPNLYYEVRQKPSSAQNCIEDIVKLINGRYKGLSGIIYCFSQKDAEQVTMSLQKLGIKAGTYHANMEPKDKSRVHKRWCANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDQRADCILYYGFGDIFRISTMVVMENVGQQKLYGMVSYCHDMGRCRRVQIAHHFDEAWDSASCNKMCDNCCQEET-LEKMDVAEHCRDLLKILEQVDQRKEKFTPLKLIDAWLGKGLSKLGLEIAAPRLP----REVLERIVAHLILQQYLKEDFSFTAFATISYVKIGPR 574

[Close]

BLAST of ATP-dependent DNA helicase vs. TrEMBL
Match: A0A091T4B1 (ATP-dependent DNA helicase (Fragment) OS=Phaethon lepturus OX=97097 GN=N335_01061 PE=3 SV=1)

HSP 1 Score: 419.468 bits (1077), Expect = 7.639e-134
Identity = 246/609 (40.39%), Postives = 360/609 (59.11%), Query Frame = 1

Query:  112 IDKRIVAIDNEIKTLTHEKEDLIKKKKQLSISTKGHS-----------ITSNKDYGKENFPWSSNIKKLLQDKFKIKNFKSLQLKTINATLDKLDCIFISSPGSGKSLCYQLASMIS-GFTLVIAPLGSLIQDQMIVSEKFGISCISLDSNSSVKIQNEIFKAMETDPVD-NVTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRLVIDEIHCCSELSHDFRQDYKNLHGLKSLYPNLPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEVKF-LSNEKKEGEEICKLIKSRFDGQSGIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNENCKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFWKLAEYFKIGSNIFTEKSGIPNLNIMNRYILDDCTCKRVSLSSILDEKFTVNDCKNMCSVCADTESEMSSIDIADVYKSALTIIKNIEKTKNPKITGKKIISELANQMSLYFADLANRFPGIDYKLFLDKAFCHLVLVGYLKLDYSFGSFSNFTYVIAGSK-TLKSNEKIDIPIRIAKSDKMRNLVQNVKQNESSNVKKS 1893
            I+  + A++ +I+ L  ++++LI+KK ++    K  S            TS + + K++FPW   IK +LQ KFK++ F+SLQL+TINA L   D   +   G GKSLCYQL ++ S GFTLVI PL SL++DQ++V E+ GIS   L+++SS     E  K + T+ +D N   KLIY TP+KI+ SK     +EKAY    L R+ +DE+HCCS+  HDFR DYK+L  LK  +PN P++GLTATA N V+ D +  L++  +C+    ++NR N++YEV+   SN +   E+I K++  R+ G SGIV+CF+QKD E +T  L   GI A +Y+  +    K  +H  W     +V+VAT AFGMGIDKP+VRFVIH SMSKS+ENYYQESGRAGRD +++DCIL++   + F+I S +  E  G   L  M  Y  +   C+RV ++   DE +   +C  MC  C   E+    +DI   YK  + I++  E   + K+T  K+I   + +    F  +A   P    +  L++   HL+L  YLK D+SF +F+  +Y+  G K +L  NE   I I+   + K    V   K ++SSN+K S
Sbjct:    9 IENELQAVEMQIQELVDKQQELIEKKMRVESLIKQSSGDPEAGGSKDNETSAEAWNKKDFPWYEKIKTVLQSKFKLQKFRSLQLETINAALAGKDIFLVMPTGGGKSLCYQLPAVCSDGFTLVICPLISLMEDQLMVLEQLGISAALLNASSS----KEHVKWVHTEMLDRNSQLKLIYVTPEKIAKSKMFMSKLEKAYQAGCLARIAVDEVHCCSQWGHDFRPDYKSLGILKRQFPNAPLIGLTATATNHVLKDAQKILHVQ-NCITFTASFNRPNLYYEVRHKPSNNEDFIEDIVKIVNGRYKGLSGIVYCFSQKDSEQVTVSLQKLGIKAGTYHANMDAKYKTKVHKGWAANQIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDQKADCILYYGFGDIFRISSMVVMENVGQEKLYDMVSYCQNMNKCRRVLIAHHFDEVWDSANCNRMCDNCC-RENSCEKMDITGYYKDLIKILEQAENM-SEKLTPLKLIDAWSGKGVSKFR-VAEVTPPKHPREELERIIAHLLLQQYLKEDFSFTAFATISYLKIGPKASLLKNEAHVITIQGIANKKS---VCKDKPSQSSNLKGS 606

[Close]

BLAST of ATP-dependent DNA helicase vs. TrEMBL
Match: A0A3Q0CWF0 (ATP-dependent DNA helicase OS=Mesocricetus auratus OX=10036 GN=Recql PE=3 SV=1)

HSP 1 Score: 418.698 bits (1075), Expect = 1.111e-133
Identity = 241/606 (39.77%), Postives = 360/606 (59.41%), Query Frame = 1

Query:  130 AIDNEIKTLTHEKEDLIKKKKQLSISTK----GHSITSNKD-------YGKENFPWSSNIKKLLQDKFKIKNFKSLQLKTINATLDKLDCIFISSPGSGKSLCYQLASMIS-GFTLVIAPLGSLIQDQMIVSEKFGISCISLDSNSSVKIQNEIFKAMETDPVD-NVTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRLVIDEIHCCSELSHDFRQDYKNLHGLKSLYPNLPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEVKF-LSNEKKEGEEICKLIKSRFDGQSGIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNENCKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFWKLAEYFKIGSNIFTEKSGIPNLNIMNRYILDDCTCKRVSLSSILDEKFTVNDCKNMC-SVCADTESEMSSIDIADVYKSALTIIKNIEKTKNPKITGKKIISELANQMS--LYFAD-LANRFPGIDYKLFLDKAFCHLVLVGYLKLDYSFGSFSNFTYVIAGSK-TLKSNEKIDIPIRIAKSDK--MRNLVQNVKQNESSNV 1884
            A+D +I+ LT  +++L++KK  L+   K    G    ++ D       + KE+FPWS  +K +LQ+ FK++ F++LQL+T+N T+ + D   +   G GKSLCYQL ++ S GFTLVI PL SL++DQ++V ++ GIS   L+++SS     E  K +  + V+ N   KL+Y TP+KI+ SK     +EKAY   RL R+ +DE+HCCS+  HDFR DYK L  LK  +PN  ++GLTATA N V+ D +  L +   CL    ++NR N++YEV+    N +   E+I KLI  R+ GQSGI++CF+QKD E +T  L   GI A +Y+  +  + K  +H +W  +  +V+VAT AFGMGIDKP+VRFVIH SMSKS+ENYYQESGRAGRD  R+DCIL++   + F+I S +  E  G   L  M  Y  +   C+RV ++   DE +  + C  MC + C DT  E    +I    +  + I+K  E+  N K+T  K++     + +  L  A  +A   P  D    L+K   H +L  YLK DYSF +++  +Y+  GS+ +L SNE   + +++ +S +  +R       Q+E ++V
Sbjct:   20 AVDIQIQELTERQQELLQKKAVLTKKIKQCLEGSDAVASSDCDSSPAEWDKEDFPWSGKVKDVLQNVFKLQKFRALQLETVNVTMARKDIFLVMPTGGGKSLCYQLPALCSEGFTLVICPLISLMEDQLMVLKQLGISATMLNASSS----KEHVKWVHAEMVNKNSQLKLVYVTPEKIAKSKMFMSRLEKAYEAGRLTRIAVDEVHCCSQWGHDFRPDYKALGILKRQFPNTSLIGLTATATNHVLKDAQKILCVEK-CLTFTASFNRPNLYYEVRQKPPNAEDFIEDIVKLINGRYKGQSGIIYCFSQKDSEQVTISLQKLGIRAGTYHANMEPEDKTKVHTQWSADELQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDSRADCILYYGFGDIFRISSMVVMENVGQQKLYEMVSYCQNISKCRRVLIAQHFDEVWNADACNKMCDNCCKDTLFEKR--NITQHCRGLVKILKQAEQL-NEKLTPLKLMDAWTGKGAAKLRVAGVVAPALPRED----LEKIIAHALLQQYLKEDYSFTAYATISYLKVGSRASLLSNEAHVVTLQVTRSTQSSIRAASSEAYQSEHADV 613

[Close]

BLAST of ATP-dependent DNA helicase vs. TrEMBL
Match: A0A091RGT0 (ATP-dependent DNA helicase (Fragment) OS=Mesitornis unicolor OX=54374 GN=N332_14986 PE=3 SV=1)

HSP 1 Score: 418.313 bits (1074), Expect = 1.689e-133
Identity = 244/609 (40.07%), Postives = 360/609 (59.11%), Query Frame = 1

Query:  112 IDKRIVAIDNEIKTLTHEKEDLIKKKKQLS---------ISTKGHSITSN--KDYGKENFPWSSNIKKLLQDKFKIKNFKSLQLKTINATLDKLDCIFISSPGSGKSLCYQLASMIS-GFTLVIAPLGSLIQDQMIVSEKFGISCISLDSNSSVKIQNEIFKAMETDPVD-NVTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRLVIDEIHCCSELSHDFRQDYKNLHGLKSLYPNLPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEVKF-LSNEKKEGEEICKLIKSRFDGQSGIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNENCKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFWKLAEYFKIGSNIFTEKSGIPNLNIMNRYILDDCTCKRVSLSSILDEKFTVNDCKNMCSVCADTESEMSSIDIADVYKSALTIIKNIEKTKNPKITGKKIISELANQMSLYFADLANRFPGIDYKLFLDKAFCHLVLVGYLKLDYSFGSFSNFTYVIAGSK-TLKSNEKIDIPIRIAKSDKMRNLVQNVKQNESSNVKKS 1893
            I+  + A++ +I+ L  ++++LI+KK ++          +   G   T N  K + K++FPW   IK  LQ KFK++ F+SLQL+T+NA +   D   +   G GKSLCYQL ++IS GFTLVI PL SL++DQ++V E+ GIS   L+++SS     E  K + T+ ++ N   KLIY TP+KI+ SK     +EKAY    L R+ +DE+HCCS+  HDFR DYK+L  LK  +PN P++GLTATA N V+ D +  L++   C+    ++NR N++YEV+   SN +   E+I K+I  R+ G SGI++CF+QKD E +T  L   GI A +Y+  +    K  +H  W     +V+VAT AFGMGIDKP+VRFVIH SMSKS+ENYYQESGRAGRD +++DCIL++   + F+I S +  E  G   L  M  Y  +  TC+RV ++   DE +   +C  MC  C   E+    +DI    +  + I++  E   + K+T  K+I   + +  +    +A   P    +  L++   HL+L  YLK D+SF +F+  +Y+  G K +L +NE   I I+   S K    V   K ++SSNVK S
Sbjct:    9 IENELQAVEMQIQELVDKQQELIQKKMRVKNLIKQSAGDLEAGGSKDTENSAKAWNKKDFPWYEKIKTALQSKFKLQKFRSLQLETVNAAMAGKDIFLVMPTGGGKSLCYQLPAVISDGFTLVICPLISLMEDQLMVLEQLGISATLLNASSS----KEHVKWVHTEMLNRNSQLKLIYVTPEKIAKSKMFMSKLEKAYQAGCLARIAVDEVHCCSQWGHDFRPDYKSLGILKRQFPNTPLIGLTATATNHVLKDAQKILHVQK-CITFTASFNRPNLYYEVRHKPSNNEDFIEDIVKIINGRYKGLSGIIYCFSQKDSEQVTVSLQKLGIKAGTYHANMDAKYKTKVHKGWAANQIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDQKADCILYYGFGDIFRISSMVVMENVGQEKLYDMVSYCQNTNTCRRVLIAHHFDEVWDSANCNRMCDNCC-RENSCEKMDITGYCRDLIKILEQAENM-SEKLTPLKLIDAWSGK-GVSKLRVAEVTPPKHPREKLERIIAHLLLQQYLKEDFSFTAFATISYLKTGPKASLLNNEAHVITIQGITSTKS---VYKDKPSQSSNVKGS 606

[Close]

BLAST of ATP-dependent DNA helicase vs. Ensembl Cavefish
Match: recql (RecQ like helicase [Source:NCBI gene;Acc:103027659])

HSP 1 Score: 368.237 bits (944), Expect = 1.487e-117
Identity = 209/567 (36.86%), Postives = 320/567 (56.44%), Query Frame = 1

Query:  235 KDYGKENFPWSSNIKKLLQDKFKIKNFKSLQLKTINATLDKLDCIFISSPGSGKSLCYQLASMIS-GFTLVIAPLGSLIQDQMIVSEKFGISCISLDSNSSVKIQNEIFKAMETDPVDNVTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRLVIDEIHCCSELSHDFRQDYKNLHGLKSLYPNLPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEVKFLSNEKKEGEEICKLIKSRFDGQSGIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNENCKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFWKLAEYFKIGSNIFTEKSGIPNLNIMNRYILDDCTCKRVSLSSILDEKFTVNDCKNMCSVCADTESEMSSIDIADVYKSALTIIKNIE--KTKNPKITGKKIISELANQMSLYFADLANRFPGIDYKLFLDKAFCHLVLVGYLKLDYSFGSFSNFTYVIAGSK-----------TLKSNEKIDIPIRIAKSDKMRNLVQNVKQNESSNVKKS 1893
            + Y + +F WS ++++ L++ FKI  F+ LQ   IN ++   D   +   G GKSLCYQL ++ S GFTLVIAPL SL++DQ++  +  G+S ++L+++SS +    +   M TD   N  +KL+Y TP+KI+ SK L   +EKAY    L R+ +DE+HCCS+  HDFR DYK L  LK  +P +P++GLTATA ++++ D +  L +  D +     +NR N++YEV+  S+E   GE I  LIK R+  QSGIV+ F+QKD E +  +L   GILA  Y+  +    K  +H  W  +  +V+VAT AFGMGIDK +VRFVIH ++SKS+ENYYQESGRAGRD   +DCI+F+  ++ F+I + +  E +G   L  M  Y  +   C+R  ++   DE +   +C  MC VC      ++     D+ K A  ++K +E   + + K+T  K+      + +     +      I  +  ++    HL+L GY   D+SF  ++ + Y+ AG K           T+K   K+  P       ++   V +VK +E S  K S
Sbjct:   75 QHYEESDFSWSKDVQEKLENIFKISKFRPLQRAAINLSMSGRDLFLVMPTGRGKSLCYQLPAVCSKGFTLVIAPLVSLMEDQLMYLKSVGVSAVTLNASSSKEDSKFVMAGM-TD--KNSPFKLLYVTPEKIAKSKLLMSKLEKAYNMGLLERIAVDEVHCCSQWGHDFRPDYKLLGILKRQFPKVPLVGLTATATSNILKDCQKILCV-PDPVTLTAPFNRPNLYYEVRVKSSEDSNGE-IAALIKGRYKDQSGIVYVFSQKDAELVAIDLQQRGILAQPYHANMEPSDKSRVHRHWSTKKIQVVVATVAFGMGIDKADVRFVIHHTISKSIENYYQESGRAGRDDHPADCIVFYGFSDIFRISTMVVMENTGQQKLQNMVAYCQNVDRCRRAMMAVHFDEVWDDEECHQMCDVCRHGNDYVT----MDITKHARDVVKLVELASSVDEKMTPLKVCDTWMGKGNAKLRKMIQT--TILSRQEVESIIVHLLLNGYFSEDFSFTPYTTYFYLKAGRKAALLKSENHSITMKMKRKVPTP----SPGRLSVAVSSVKDSEGSGAKSS 626

[Close]

BLAST of ATP-dependent DNA helicase vs. Ensembl Cavefish
Match: recql (RecQ like helicase [Source:NCBI gene;Acc:103027659])

HSP 1 Score: 364.385 bits (934), Expect = 2.278e-114
Identity = 202/540 (37.41%), Postives = 309/540 (57.22%), Query Frame = 1

Query:  235 KDYGKENFPWSSNIKKLLQDKFKIKNFKSLQLKTINATLDKLDCIFISSPGSGKSLCYQLASMIS-GFTLVIAPLGSLIQDQMIVSEKFGISCISLDSNSSVKIQNEIFKAMETDPVDNVTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRLVIDEIHCCSELSHDFRQDYKNLHGLKSLYPNLPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEVKFLSNEKKEGEEICKLIKSRFDGQSGIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNENCKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFWKLAEYFKIGSNIFTEKSGIPNLNIMNRYILDDCTCKRVSLSSILDEKFTVNDCKNMCSVCADTESEMSSIDIADVYKSALTIIKNIE--KTKNPKITGKKIISELANQMSLYFADLANRFPGIDYKLFLDKAFCHLVLVGYLKLDYSFGSFSNFTYVIAGSK-----------TLKSNEKIDIP 1812
            + Y + +F WS ++++ L++ FKI  F+ LQ   IN ++   D   +   G GKSLCYQL ++ S GFTLVIAPL SL++DQ++  +  G+S ++L+++SS +    +   M TD   N  +KL+Y TP+KI+ SK L   +EKAY    L R+ +DE+HCCS+  HDFR DYK L  LK  +P +P++GLTATA ++++ D +  L +  D +     +NR N++YEV+  S+E   GE I  LIK R+  QSGIV+ F+QKD E +  +L   GILA  Y+  +    K  +H  W  +  +V+VAT AFGMGIDK +VRFVIH ++SKS+ENYYQESGRAGRD   +DCI+F+  ++ F+I + +  E +G   L  M  Y  +   C+R  ++   DE +   +C  MC VC      ++     D+ K A  ++K +E   + + K+T  K+      + +     +      I  +  ++    HL+L GY   D+SF  ++ + Y+ AG K           T+K   K+  P
Sbjct:   75 QHYEESDFSWSKDVQEKLENIFKISKFRPLQRAAINLSMSGRDLFLVMPTGRGKSLCYQLPAVCSKGFTLVIAPLVSLMEDQLMYLKSVGVSAVTLNASSSKEDSKFVMAGM-TD--KNSPFKLLYVTPEKIAKSKLLMSKLEKAYNMGLLERIAVDEVHCCSQWGHDFRPDYKLLGILKRQFPKVPLVGLTATATSNILKDCQKILCV-PDPVTLTAPFNRPNLYYEVRVKSSEDSNGE-IAALIKGRYKDQSGIVYVFSQKDAELVAIDLQQRGILAQPYHANMEPSDKSRVHRHWSTKKIQVVVATVAFGMGIDKADVRFVIHHTISKSIENYYQESGRAGRDDHPADCIVFYGFSDIFRISTMVVMENTGQQKLQNMVAYCQNVDRCRRAMMAVHFDEVWDDEECHQMCDVCRHGNDYVT----MDITKHARDVVKLVELASSVDEKMTPLKVCDTWMGKGNAKLRKMIQT--TILSRQEVESIIVHLLLNGYFSEDFSFTPYTTYFYLKAGRKAALLKSENHSITMKMKRKVPTP 603

[Close]

BLAST of ATP-dependent DNA helicase vs. Ensembl Cavefish
Match: recql (RecQ like helicase [Source:NCBI gene;Acc:103027659])

HSP 1 Score: 363.614 bits (932), Expect = 2.665e-114
Identity = 202/540 (37.41%), Postives = 309/540 (57.22%), Query Frame = 1

Query:  235 KDYGKENFPWSSNIKKLLQDKFKIKNFKSLQLKTINATLDKLDCIFISSPGSGKSLCYQLASMIS-GFTLVIAPLGSLIQDQMIVSEKFGISCISLDSNSSVKIQNEIFKAMETDPVDNVTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRLVIDEIHCCSELSHDFRQDYKNLHGLKSLYPNLPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEVKFLSNEKKEGEEICKLIKSRFDGQSGIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNENCKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFWKLAEYFKIGSNIFTEKSGIPNLNIMNRYILDDCTCKRVSLSSILDEKFTVNDCKNMCSVCADTESEMSSIDIADVYKSALTIIKNIE--KTKNPKITGKKIISELANQMSLYFADLANRFPGIDYKLFLDKAFCHLVLVGYLKLDYSFGSFSNFTYVIAGSK-----------TLKSNEKIDIP 1812
            + Y + +F WS ++++ L++ FKI  F+ LQ   IN ++   D   +   G GKSLCYQL ++ S GFTLVIAPL SL++DQ++  +  G+S ++L+++SS +    +   M TD   N  +KL+Y TP+KI+ SK L   +EKAY    L R+ +DE+HCCS+  HDFR DYK L  LK  +P +P++GLTATA ++++ D +  L +  D +     +NR N++YEV+  S+E   GE I  LIK R+  QSGIV+ F+QKD E +  +L   GILA  Y+  +    K  +H  W  +  +V+VAT AFGMGIDK +VRFVIH ++SKS+ENYYQESGRAGRD   +DCI+F+  ++ F+I + +  E +G   L  M  Y  +   C+R  ++   DE +   +C  MC VC      ++     D+ K A  ++K +E   + + K+T  K+      + +     +      I  +  ++    HL+L GY   D+SF  ++ + Y+ AG K           T+K   K+  P
Sbjct:   75 QHYEESDFSWSKDVQEKLENIFKISKFRPLQRAAINLSMSGRDLFLVMPTGRGKSLCYQLPAVCSKGFTLVIAPLVSLMEDQLMYLKSVGVSAVTLNASSSKEDSKFVMAGM-TD--KNSPFKLLYVTPEKIAKSKLLMSKLEKAYNMGLLERIAVDEVHCCSQWGHDFRPDYKLLGILKRQFPKVPLVGLTATATSNILKDCQKILCV-PDPVTLTAPFNRPNLYYEVRVKSSEDSNGE-IAALIKGRYKDQSGIVYVFSQKDAELVAIDLQQRGILAQPYHANMEPSDKSRVHRHWSTKKIQVVVATVAFGMGIDKADVRFVIHHTISKSIENYYQESGRAGRDDHPADCIVFYGFSDIFRISTMVVMENTGQQKLQNMVAYCQNVDRCRRAMMAVHFDEVWDDEECHQMCDVCRHGNDYVT----MDITKHARDVVKLVELASSVDEKMTPLKVCDTWMGKGNAKLRKMIQT--TILSRQEVESIIVHLLLNGYFSEDFSFTPYTTYFYLKAGRKAALLKSENHSITMKMKRKVPTP 603

[Close]

BLAST of ATP-dependent DNA helicase vs. Ensembl Cavefish
Match: blm (BLM RecQ like helicase [Source:NCBI gene;Acc:103043866])

HSP 1 Score: 297.36 bits (760), Expect = 4.526e-86
Identity = 174/470 (37.02%), Postives = 259/470 (55.11%), Query Frame = 1

Query:  253 NFPWSSNIKKLLQDKFKIKNFKSLQLKTINATLDKLDCIFISSPGSGKSLCYQLASMIS-GFTLVIAPLGSLIQDQMIVSEKFGISCISLDSNSSVKIQNEIFKAM-ETDPVDNVTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRLVIDEIHCCSELSHDFRQDYKNLHGLKSLYPNLPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEVKFLSNEKKEGEEICKLIKSRFDGQSGIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNEN-CKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFWKLAEYFKIGSNIFTEKSG--------IPNLNIMNRYILDDCTCKRVSLSSILDE-KFTVNDCKNMCSVCADTESEMSSIDIADVYKSALTIIKNIEKTKNPKITGKKIISELANQMSL 1626
            +FP SS + K+   +F +  F+  QL+ INATL   D   +   G GKSLCYQL + +S G T+VI+PL SLI DQ+       I   SL  + S      I+  + + DPV     KL+Y TP+K+S S ++  A++  Y    L R VIDE HC S+  HDFR DYK LH L+  +PN+P++ LTATA   V  DI   + +N    V   ++NR N+ Y V      KK  EE    IK  +   SGI++C ++ DC+ + + L   GI A +Y+  L    ++ + NKW+N++ C+V+ AT AFGMGIDKP+VR+VIH S+ KS+E YYQESGRAGRDG+ S C+LF+  ++  +I   +  +K G          NL+ M  +  +   C+R+ L +   E KF  + CK    V  D  +        +V +    I++ +++    K+ G+   S   N+++L
Sbjct:  641 SFPHSSEMMKIFHKRFGLHQFRFNQLEAINATLLGEDTFVLMPTGGGKSLCYQLPACVSAGVTVVISPLRSLIVDQVQKLTTLDIPATSLSGDKSESEAGRIYMQLSKKDPV----IKLLYATPEKVSASGRMISALQNLYERNLLARFVIDEAHCVSQWGHDFRPDYKRLHELRQKFPNVPIMALTATATPRVQKDILNQMAMNRP-QVFTMSFNRHNLKYSV-LPKKPKKVDEECINWIKKYYPRDSGIIYCLSRNDCDTMADSLQRAGIAALAYHAGLNDKDREYVQNKWINQDRCQVMCATIAFGMGIDKPDVRYVIHASLPKSVEGYYQESGRAGRDGEISHCVLFYSYSDVIRIKRILAMDKDGNHHSRATHTNNLHSMVHFCENVSECRRIQLLAYFGENKFNADFCKEHPEVICDNCARPHQYKARNVTEDVKKIVRFVQENCQ-KVGGRYSKSSQQNRLTL 1103

[Close]

BLAST of ATP-dependent DNA helicase vs. Ensembl Cavefish
Match: recql5 (RecQ like helicase 5 [Source:NCBI gene;Acc:103031687])

HSP 1 Score: 217.238 bits (552), Expect = 3.167e-59
Identity = 139/427 (32.55%), Postives = 217/427 (50.82%), Query Frame = 1

Query:  274 IKKLLQDKFKIKNFKSLQLK-TINATLDKLDCIFISSP-GSGKSLCYQLASMIS-GFTLVIAPLGSLIQDQMIVSEKFGISCISLDSNSSVKIQNEIFKAMETD-PVDNVTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRLVIDEIHCCSELSHDFRQDYKNLHGLKSLYPNLPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEVKFLSNEKKEGEEICKLIKSRFDGQS-----GIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNENCKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFWKLAEYFKI---------------GSNIFTEKSGIPNLNIMNRYILDDCTCKRVSLSSIL-DEKFTVNDCKNMCSVC 1479
            +++ L+  F  + F+S Q +  + A L+    +F+  P G+GKSLCYQL ++++ G TLVI+PL +LIQDQ+   ++  I   S++S      + +I + +E++ PV     K++Y TP+ ++ S      +        L RL +DE HC S+  HDFR DY  L  L++  P +P + LTATA   V  DI  +L L S  L       R N+ Y+V F          +    K    G S     GIV+C  ++ CE++ + L   GI+A  Y+  L    + +    W+     VIVAT +FGMG+DK NVRFV H +++KSL +YYQESGRAGRDG  S C +++   +  ++               GS    +K+ I +   M  +   +  C+  ++S    D+K    +C   C  C
Sbjct:    6 VERALKTHFGFERFRSRQQEEVVRAVLEGERDVFVCMPTGAGKSLCYQLPALLATGITLVISPLIALIQDQVEHLKELNIPARSINSKLPAGERRQILEDLESESPV----LKMLYITPEMVA-SPSFQPCLSSLCSRGLLARLAVDEAHCVSQWGHDFRPDYLKLGELRARLPGVPCVALTATAPKRVQEDIARSLRLRSP-LTFSTPVFRKNLKYDVIFRDLLPDPYVHLHAFAKEALGGSSAEKGCGIVYCRTRESCEDVAHRLTKLGIVAKPYHAGLKAGDRTESQADWMAGKVPVIVATISFGMGVDKANVRFVAHWNVAKSLASYYQESGRAGRDGIPSSCRIYYSRKDRDQLNFLIRKEVSRKQEKRGSEKEQDKAAIQDFEAMVNFCEQE-GCRHATISQFFGDQK---PNCAGSCDYC 422

[Close]

BLAST of ATP-dependent DNA helicase vs. Ensembl Sea Lamprey
Match: recql (RecQ helicase-like [Source:ZFIN;Acc:ZDB-GENE-050809-134])

HSP 1 Score: 355.91 bits (912), Expect = 3.503e-114
Identity = 197/577 (34.14%), Postives = 329/577 (57.02%), Query Frame = 1

Query:  109 EIDKRIVAIDNEIKTLTHEKEDLIKKKKQLS-------------ISTKGHSITSNKDYGKENFPWSSNIKKLLQDKFKIKNFKSLQLKTINATLDKLDCIFISSPGSGKSLCYQLASMIS-GFTLVIAPLGSLIQDQMIVSEKFGISCISLDSNSSVKIQNEIFKAMETDPVDNVTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRLVIDEIHCCSELSHDFRQDYKNLHGLKSLYPNLPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEVKFLSNEKKE-GEEICKLIKSRFDGQSG--IVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNENCKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFWKLAEYFKIGSNIFTEKSGIPNLNIMNRYILDDCTCKRVSLSSILDEKFTVNDCKNMCSVCAD--TESEMSSIDIADVYKSALTIIKNIEKTKNPKITGKKIISELANQMSLYFADLANRFPGIDYKLFLDKAFCHLVLVGYLKLDYSFGSFSNFTYVIAGSKT 1782
            E+D+    +  +I+ L  ++E L+++K  +               S    S  + + + +E+F WS+ +K +L++ FK+ NF+SLQL+ +NA++   D   I   G GKSLCYQL ++ S GFTLVI+PL SL++DQ++  E+  I    L ++S+ +    +  AM ++   +   KL+Y TP+KI+ SK     +EKAY  +RL R+ IDE+HCCS+  +DFR DYK L  LK  +P +P+L LTATA + V++D+K+ L +    L    ++NR N+ Y+V     + ++  E + +LI  ++ GQSG  IV+CF++KD E +   L + G+ A SY+  +  D +  +H  W +   +V+VAT AFGMGIDKP+VRFVIH S+SKS+ENYYQESGRAGRDG  +DC+L++   + F+    +  E++G   L  M  Y      C+R  ++   DE +    C  MC  C       E S +  A   +  + I+++ ++ K  K+T  +++     + ++     +   P +  +   +     L+++GY++ +YS+  ++  +Y++ G K 
Sbjct:   21 ELDR----VGTQIQELVEQQELLLERKASIQNKISKLQRKQSKEQSGSADSARAAEKWEREDFSWSTKLKCILREVFKMDNFRSLQLQAMNASIAGHDVFLIMPTGGGKSLCYQLPALCSKGFTLVISPLISLMEDQIMALEQLKIPAAMLSASSTKEHVKTVQAAMISN---DHELKLLYVTPEKIAKSKIFMSKLEKAYKGERLARIAIDEVHCCSQWGNDFRPDYKVLGILKRQFPKVPLLCLTATATSVVLDDVKSILAVPG-ALSFTASFNRPNLHYQVHRKPTKFEDCMENMVRLINKKYKGQSGPGIVYCFSRKDAEEVAAALTSLGVGAGSYHSDIPADRRSRLHRHWTSNRLQVVVATVAFGMGIDKPDVRFVIHHSLSKSMENYYQESGRAGRDGAPADCVLYYSFPDVFRQSQMVSMERTGQEKLYGMVAYCQTYNRCRRSLIAEHFDEVWDAAQCDRMCDHCRGGVVAEEASVVRHA---RGLIAILRHAQQ-KQEKLTPLRLLEAWQGRGAVKLRVSSVPTPSLSQQ-GCEIIVLQLLMLGYIREEYSYTPYATISYLVVGQKA 584

[Close]

BLAST of ATP-dependent DNA helicase vs. Ensembl Sea Lamprey
Match: blm (BLM RecQ like helicase [Source:ZFIN;Acc:ZDB-GENE-070702-5])

HSP 1 Score: 285.419 bits (729), Expect = 5.807e-86
Identity = 162/454 (35.68%), Postives = 250/454 (55.07%), Query Frame = 1

Query:  238 DYGKENFPWSSNIKKLLQDKFKIKNFKSLQLKTINATLDKLDCIFISSPGSGKSLCYQLASMIS-GFTLVIAPLGSLIQDQMIVSEKFGISCISLDSNSSVKIQNEIFKAM-ETDPVDNVTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRLVIDEIHCCSELSHDFRQDYKNLHGLKSLYPNLPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEVKFLSNEKKEGEEICKLIKSRFDGQSGIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNE-NCKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFWKLAEYFKIGSNIFTEKSG---------IPNLNIMNRYILDDCTCKRVSLSSILDEK-FTVNDCKNMCSVCADTESEMSSIDIADVYKSALTIIKNIE 1560
            ++   +FP S+ + K+ + KF +  F+  QL+ INA +   DC  +   G GKSLCYQL + +S G ++V++PL SLI DQ+       I    L  + +      I+  + + +PV     KL+Y TP+K+S S +L  A++  Y  + L R VIDE HC S+  HDFR DYK L  L+  +P +P++ LTATA   V  DI   L +N+       ++NR N+ YEV      KK  E+  + I+S +   SGI++C ++ +C+ +   L   G+ A SY+  L    +      W+N+  CKVI AT AFGMGIDKP+VR+VIH S+ KS+E YYQESGRAGRDG  + C+LF+   +  ++   I +E+ G         + NL  M  +  +   C+R+ L +   EK F    C+   +V  D  S M +  + DV ++  T+++ ++
Sbjct:   91 EFQGTSFPHSAEMLKVFRHKFGLLRFRKNQLEAINAAMFNRDCFVLMPTGGGKSLCYQLPACLSPGVSVVVSPLRSLIVDQVQRLASLDIPATHLSGDINDGDLAAIYMQLAKKEPV----VKLLYVTPEKLSCSTRLLSALDNLYQRQLLSRFVIDEAHCVSQWGHDFRPDYKRLSELRRRFPTVPIMALTATATTRVQTDILHQLTMNAPLSGFIQSFNRDNLKYEV-LPKKPKKVAEDCLQWIRSNYPRDSGIIYCLSRHECDTMAESLRRAGLDALSYHAGLTDKQRDQSQQCWINQRRCKVICATIAFGMGIDKPDVRYVIHASLPKSIEGYYQESGRAGRDGIVAKCVLFYGYGDVTRLRRIIHSEREGGSRESKQMHMSNLYSMVHFCENISECRRLQLLAYFGEKGFDPGFCRKNPTVACDNCSSMQTFRLRDVTENVKTVVRFLQ 539

[Close]

BLAST of ATP-dependent DNA helicase vs. Ensembl Sea Lamprey
Match: recql5 (RecQ helicase-like 5 [Source:ZFIN;Acc:ZDB-GENE-071214-1])

HSP 1 Score: 223.402 bits (568), Expect = 3.240e-64
Identity = 147/466 (31.55%), Postives = 233/466 (50.00%), Query Frame = 1

Query:  274 IKKLLQDKFKIKNFKS-LQLKTINATLDKLDCIFISSP-GSGKSLCYQL-ASMISGFTLVIAPLGSLIQDQMIVSEKFGISCISLDSNSSVKIQNEIFKAMETDPVDNVTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRLVIDEIHCCSELSHDFRQDYKNLHGLKSLYPNLPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEVKF---LSNEKKEGEEIC------KLIKSRFDGQSGIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNENCKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFW--------------KLAEYFK--IGSNIFTEKSGIPNLNIMNRYILDDCTCKRVSLSSILDEKFTVNDCKNMCSVCADTESEMSSIDIADVYKSA----LTIIKNIEKTKNP 1575
            ++  L   F  + F+S LQ     A       +F+S P G+GKSLCYQL A M  G +LVI PL +LIQDQ+    +  I   +L+S      +  + + +  DP    + K++Y TP+ ++ +      + +    + L  LV+DE HC S+  HDFR DY  L  L+SL   +P + LTATA   V  DI + L+L+    + K +  R N+FY V +   + +  K+  + C      K     FDG SGIV+   ++ C+ L +EL   G+   +Y+  L  D +  +  +W+     VIVAT +FGMG+DK NVRFV H +++KS+  YYQESGRAGRDGK + C L++               +A  F+   G    T+K+ +     +  +  +   C+  +++    +K  + DC++ C  C D+   +  +D      S+     T I+  +K   P
Sbjct:    1 VRDTLGRVFGFEAFRSALQEDAARAVASGTKDVFVSMPTGAGKSLCYQLPAVMAPGVSLVICPLIALIQDQLDHLHQLNIPARTLNSKMGAHERQAVVEDLHADPP---SLKMLYITPE-MAATHSFGAVLGRLASRQLLSCLVVDEAHCVSQWGHDFRPDYLKLGRLRSLLRGVPCVALTATATKQVQEDIVSILSLDKPA-IFKSSCFRPNLFYNVSYKEVIQDPYKDLTQFCLKALGKKNAAGGFDG-SGIVYSRTRESCDMLAHELTKRGVKTKAYHAGLKTDDRSKVQVEWMEGETPVIVATISFGMGVDKANVRFVAHWNIAKSMAGYYQESGRAGRDGKPAFCRLYYCRKERGQVSFLISKDIAAMFQDDTGKVSETDKAAMAGFEALVNFC-EKLGCRHKAIAQYFGDK--IADCRSACDSCKDSALVVQDLDALQKVGSSKSFGRTAIQQPQKASGP 457

[Close]

BLAST of ATP-dependent DNA helicase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005409.1 (pep scaffold:Pmarinus_7.0:GL485130:385:11513:1 gene:ENSPMAG00000004903.1 transcript:ENSPMAT00000005409.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 84.7297 bits (208), Expect = 2.750e-17
Identity = 48/158 (30.38%), Postives = 84/158 (53.16%), Query Frame = 1

Query: 1066 ASSYYGTLGYDIKKDIHNKWLNENCKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFWKLAEYFKIGSNIFTEKSGIPNLNIMNRYILDDCTCKRVSLSSILDEKFTVNDCK--NMCSVCADTESEMSSI---DIADV 1524
            A SY+  +    +K +  +++    +++VAT AFGMG+DK +VR ++H +M KS E+Y QE GRAGRDG+ + C +F                 S   +L  + R+I  + T  R+++  +L + F    C+  ++C    +TE E   +   ++AD+
Sbjct:  139 AESYHAGMTAAERKAVQTRFMRGALRIVVATVAFGMGLDKADVRAIVHYNMPKSFESYVQEIGRAGRDGEPAHCHMFL---------------DSEARDLQELRRHIYAN-TIDRITVKKLLQKVFPACKCRELHLCRQRLETEEEFGYVRDDEMADI 280

[Close]

BLAST of ATP-dependent DNA helicase vs. Ensembl Sea Lamprey
Match: DDX41 (DEAD-box helicase 41 [Source:HGNC Symbol;Acc:HGNC:18674])

HSP 1 Score: 51.6026 bits (122), Expect = 9.013e-8
Identity = 27/100 (27.00%), Postives = 47/100 (47.00%), Query Frame = 1

Query:  997 IVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNENCKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILF 1296
            ++F   + D + +   L+  G+ A + +G    + +      +      V+VAT+    G+D PN++ VI+  M + +ENY    GR GR GK      F
Sbjct:   50 LIFAEKKADVDAIHEYLLLKGVEAVAIHGGKDQEERTKAMESFREGKKDVLVATDVASKGLDFPNIQHVINYDMPEEIENYVHRIGRTGRSGKTGIATTF 149

[Close]

BLAST of ATP-dependent DNA helicase vs. Ensembl Yeast
Match: SGS1 (RecQ family nucleolar DNA helicase; role in genome integrity maintenance, chromosome synapsis, meiotic joint molecule/crossover formation; stimulates activity of Top3p; rapidly lost in response to rapamycin in Rrd1p-dependent manner; forms nuclear foci upon DNA replication stress; yeast SGS1 complements mutations in human homolog BLM implicated in Bloom syndrome; also similar to human WRN implicated in Werner syndrome; human BLM and WRN can each complement yeast null mutant [Source:SGD;Acc:S000004802])

HSP 1 Score: 285.034 bits (728), Expect = 9.515e-83
Identity = 181/540 (33.52%), Postives = 285/540 (52.78%), Query Frame = 1

Query:  256 FPWSSNIKKLLQDKFKIKNFKSLQLKTINATLDKLDCIFISSPGSGKSLCYQLASMI-----SGFTLVIAPLGSLIQDQMIVSEKFGISCISLDSNSSVKIQNEIFKAMETDPVDNVTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRLVIDEIHCCSELSHDFRQDYKNLHGLKSLYPNLPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEVKFLSNEKKEGE--EICKLIKSRFDGQSGIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNENCKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFWKLAEYFKIGSNIFTEK-----SGIPNLNIMNRYIL--DDCT-CKRVSLSSILDEKFTVNDCKNMCSVCADTESEMSSIDIADVYKSALTIIKNIEKTKNPKIT------------GKKIISELANQMSLYFADLANRFPGIDYKLFLDKAFCHLVLVGYLKLDYSFGSFSNF--TYVIAGSKTLK 1788
            +PWS  +   L + FK+  F+  QL+ +NATL   D   +   G GKSLCYQL +++      G T+VI+PL SL+QDQ+       I      S  + + + + F       +D     L+Y +P+ IS S++  +AI + Y D +L R+V+DE HC S   HDFR DYK L   K  YP++P++ LTATA+  V  DI   L L     + K ++NR+N++YEV    N+K +    EIC  +KSRF  Q+GI++C ++K CE  + ++  NGI  + Y+  +  D +  +   W  +  +VI AT AFGMGIDKP+VRFV H ++ ++LE YYQE+GRAGRDG  S CI ++   +   + + I  +K     +   +LN + + +   D+ T C+R  + S  +E F    C   C  C ++ + ++  +  DV + A  I+K +E  +N ++T              KI+   AN  +L    +         K  +++ F HL+ +  L+ +YS  + S F  +YV  G    K
Sbjct:  660 YPWSDEVLYRLHEVFKLPGFRPNQLEAVNATLQGKDVFVLMPTGGGKSLCYQLPAVVKSGKTHGTTIVISPLISLMQDQVEHLLNKNIKASMFSSRGTAEQRRQTFNLFINGLLD-----LVYISPEMISASEQCKRAISRLYADGKLARIVVDEAHCVSNWGHDFRPDYKELKFFKREYPDIPMIALTATASEQVRMDIIHNLELKEPVFL-KQSFNRTNLYYEV----NKKTKNTIFEICDAVKSRFKNQTGIIYCHSKKSCEQTSAQMQRNGIKCAYYHAGMEPDERLSVQKAWQADEIQVICATVAFGMGIDKPDVRFVYHFTVPRTLEGYYQETGRAGRDGNYSYCITYFSFRDIRTMQTMIQKDKNLDRENKEKHLNKLQQVMAYCDNVTDCRRKLVLSYFNEDFDSKLCHKNCDNCRNSANVIN--EERDVTEPAKKIVKLVESIQNERVTIIYCQDVFKGSRSSKIVQ--ANHDTLEEHGIGKSM----QKSEIERIFFHLITIRVLQ-EYSIMNNSGFASSYVKVGPNAKK 1180

[Close]

BLAST of ATP-dependent DNA helicase vs. Ensembl Yeast
Match: HRQ1 (3'-5' DNA helicase that has DNA strand annealing activity; helicase activity is stimulated by fork structure and 3'-tail length of substrates; acts with Rad4p in nucleotide-excision repair; belongs to the widely conserved RecQ family of proteins which are involved in maintaining genomic integrity; similar to the human RecQ4p implicated in Rothmund-Thomson syndrome (RTS) [Source:SGD;Acc:S000002699])

HSP 1 Score: 79.7221 bits (195), Expect = 7.433e-16
Identity = 89/350 (25.43%), Postives = 150/350 (42.86%), Query Frame = 1

Query:  307 KNFKSLQLKTINATLDKLDCIFISSPGSGKSLCYQLASM------ISGFTLVIAPLGSLIQDQMIVSEKFGISCISLDSNSSVKIQNEIFKAMETDPVDNV----TYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRLVIDEIHCCSEL--SHDFRQDYKNLHGLKSLYPNLPVLGLTATAN-NSVINDIKTTLNLNSDCLVHKDNYN---RSNIFYEVKFLSNEKKEGEEICK-----LIKSRFDGQSGIVFCFNQKDCENLTNELVNNGILAS---------SYYGTLGYDIKKDIHNKWLNENCKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGR 1266
            +NF S Q   IN+     + I  +S  SGKSL YQLA++           + I P  +L QDQ   + K  +S I    N+ V   +      +T+P +        ++I+T PD I  S     A  + +    L  +V+DE+H    L  SH      + L      Y N  +  ++ +A   S +  +K    +N   L+H+D      +  + +    L   +++ E   +     L++   +    I FC+ ++ CE L  E+ N  I            SY G      ++ I  +  + N K +++TNA  +GID   +  V+      S+ N++Q+SGRAGR
Sbjct:  289 ENFYSHQADAINSLHQGENVIITTSTSSGKSLIYQLAAIDLLLKDPESTFMYIFPTKALAQDQK-RAFKVILSKIPELKNAVVDTYDG-----DTEPEERAYIRKNARVIFTNPDMIHTSILPNHANWRHFL-YHLKLVVVDELHIYKGLFGSHVALVMRRLLRLCHCFYENSGLQFISCSATLKSPVQHMKDMFGINEVTLIHEDGSPTGAKHLVVWNPPILPQHERKRENFIRESAKILVQLILNNVRTIAFCYVRRVCELLMKEVRNIFIETGREDLVTEVMSYRGGYSASDRRKIEREMFHGNLKAVISTNALELGIDIGGLDAVLMCGFPLSMANFHQQSGRAGR 631

[Close]

BLAST of ATP-dependent DNA helicase vs. Ensembl Yeast
Match: FAL1 (Nucleolar protein required for maturation of 18S rRNA; member of the eIF4A subfamily of DEAD-box ATP-dependent RNA helicases; 18S rRNA biogenesis defect of the null mutant is functionally complemented by human EIF4A3 [Source:SGD;Acc:S000002428])

HSP 1 Score: 68.1662 bits (165), Expect = 1.500e-12
Identity = 50/211 (23.70%), Postives = 99/211 (46.92%), Query Frame = 1

Query:  691 LVIDEIHCCSELSHDFRQDYKNLHGLKSLYPNLPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEVKFLSNEKKEGEEICKLIKSRFDGQSGIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNENCKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFWKLAEYFKI 1323
            LV+DE       +  F+Q   ++     L  N  V+ ++AT N  ++   +  +N     LV +D  +   I   V  +  E+ + + +C +  S    Q  ++FC  +K  + L+  L+ +     S +G +  + +  + N +   + +V+++T+ +  GID   V  VI+  + + +ENY    GR+GR G++   I F   A+  K+
Sbjct:  170 LVLDEADELLSETLGFKQQIYDIFA--KLPKNCQVVVVSATMNKDILEVTRKFMNDPVKILVKRDEISLEGIKQYVVNVDKEEWKFDTLCDIYDSLTITQC-VIFCNTKKKVDWLSQRLIQSNFAVVSMHGDMKQEERDKVMNDFRTGHSRVLISTDVWARGIDVQQVSLVINYDLPEIIENYIHRIGRSGRFGRKGVAINFITKADLAKL 377

[Close]

BLAST of ATP-dependent DNA helicase vs. Ensembl Yeast
Match: DBP2 (ATP-dependent RNA helicase of the DEAD-box protein family; has strong preference for dsRNA; interacts with YRA1; required for assembly of Yra1p, Nab2p and Mex67p onto mRNA and formation of nuclear mRNP; involved in mRNA decay and rRNA processing; may be involved in suppression of transcription from cryptic initiation sites [Source:SGD;Acc:S000005056])

HSP 1 Score: 55.4546 bits (132), Expect = 1.976e-8
Identity = 85/408 (20.83%), Postives = 161/408 (39.46%), Query Frame = 1

Query:  181 KKKKQLSISTKGHSITSN-KDYGKENFPWSSNIKKLLQDKFKIKNF---KSLQLKTINATLDKLDCIFISSPGSGKSLCYQLASMI------------SGFTLVIAPLGSLIQDQMIVSEKFGIS------CISLDSNSSVKIQNEIFKAMETDPVDNVTYKLIYTTPDKI--------SNSKKLTK-AIEKA-----YGDKRLVRLVIDEIHCCSELSHDFRQDYKNLHGLKSLYPNLPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEVKFLSNEKKEGEEICKLIKSRFDGQSGIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNENCKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILF 1296
            +K+ +++IS  GH I      + +  FP        + ++ K + F     +Q +     L   D + I++ GSGK+L Y L  ++                LV+AP   L         KFG S      C+      S +I+ ++ +  E          ++  TP ++        +N K++T   +++A      G +  +R ++D+I    +         K +  L + Y N P+     +   S  ++I   + + SD     +  +R N + E     NE K                  ++F   ++ C+++T  L  +G  A + +G      +  +  ++ N    ++VAT+    GID   + +VI+  M  ++E+Y    GR GR G     I F
Sbjct:   96 RKENEMTIS--GHDIPKPITTFDEAGFP------DYVLNEVKAEGFDKPTGIQCQGWPMALSGRDMVGIAATGSGKTLSYCLPGIVHINAQPLLAPGDGPIVLVLAPTRELAVQIQTECSKFGHSSRIRNTCVYGGVPKSQQIR-DLSRGSE----------IVIATPGRLIDMLEIGKTNLKRVTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVKQLAADYLNDPIQVQVGSLELSASHNITQIVEVVSDF----EKRDRLNKYLETASQDNEYKT-----------------LIFASTKRMCDDITKYLREDGWPALAIHGDKDQRERDWVLQEFRNGRSPIMVATDVAARGIDVKGINYVINYDMPGNIEDYVHRIGRTGRAGATGTAISF 463

[Close]

BLAST of ATP-dependent DNA helicase vs. Ensembl Yeast
Match: DBP3 (RNA-Dependent ATPase, member of DExD/H-box family; involved in cleavage of site A3 within the ITS1 spacer during rRNA processing; not essential for growth, but deletion causes severe slow-growth phenotype [Source:SGD;Acc:S000003046])

HSP 1 Score: 54.6842 bits (130), Expect = 2.932e-8
Identity = 78/331 (23.56%), Postives = 140/331 (42.30%), Query Frame = 1

Query:  361 DCIFISSPGSGKSLCYQLASMISGF----------TLVIAP---LGSLIQDQMIV-SEKFGISCISLDSNSSVKIQNEIFKAMETDPVDNVTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRLVIDEIHCCSELSHDFRQDYKNLHGLKSLYPNLPVLGLTAT--------ANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEVKFLSNEKKEGEEICKLIKSRFDG----QSGIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNENCKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGK 1275
            D + ++  GSGK+  + + + IS             LVI+P   L S I D +IV ++K G+ C  +        Q    K  +          ++  TP ++     L    E +    ++  LV+DE      L   F +D KN+   ++       L  TAT        A+  + N IK ++  N+D L    N   + I   V     E+K    + +L+K    G    +  ++F   +K+   +   L  NG   ++ +G L    +    N++ +    +++AT+    G+D PNV+ VI+++   ++E+Y    GR GR G+
Sbjct:  151 DVVGVAETGSGKTFAFGVPA-ISHLMNDQKKRGIQVLVISPTRELASQIYDNLIVLTDKVGMQCCCVYGGVPKDEQRIQLKKSQ----------VVVATPGRL-----LDLLQEGSVDLSQVNYLVLDEADRM--LEKGFEEDIKNII-RETDASKRQTLMFTATWPKEVRELASTFMNNPIKVSIG-NTDQLTA--NKRITQIVEVVDPRGKERK----LLELLKKYHSGPKKNEKVLIFALYKKEAARVERNLKYNGYNVAAIHGDLSQQQRTQALNEFKSGKSNLLLATDVAARGLDIPNVKTVINLTFPLTVEDYVHRIGRTGRAGQ 455

[Close]

BLAST of ATP-dependent DNA helicase vs. Ensembl Nematostella
Match: EDO32632 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SUG5])

HSP 1 Score: 388.267 bits (996), Expect = 1.057e-126
Identity = 211/580 (36.38%), Postives = 337/580 (58.10%), Query Frame = 1

Query:  109 EIDKRIVAIDNEIKTLTHEKEDLIKKKKQLSISTKGHS-------ITSN------KDYGKENFPWSSNIKKLLQDKFKIKNFKSLQLKTINATLDKLDCIFISSPGSGKSLCYQLASMIS-GFTLVIAPLGSLIQDQMIVSEKFGISCISLDSNSSVKIQNEIFKAMETDPVDNVTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRLVIDEIHCCSELSHDFRQDYKNLHGLKSLYPNLPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEVK--------FLSNEKKEGEEICKLIKSRFDGQSGIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNENCKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFWKLAEYFKIGSNIFTEKSGIPNLNIMNRYILDDCTCKRVSLSSILDEKFTVNDCKNMCSVCADTESEMSSIDIADVYKSALTIIKNIEKTKNP--KITGKKIISELANQMSLYFADLANRFPGIDYKLFLDKAFCHLVLVGYLKLDYSFGSFSNFTYVIAGS 1776
            EI + +  I+ +I++L   ++ L+ +K++L +    +S        +SN       D+    F WS  ++  L++ FKI  F+ LQL+ INAT+  +DCI I   G GKSLC+QL +++S G TLV++PL SL++DQ+   ++ GI    L+++S+ +  N +  ++     D    K++Y TP+KI+ SK+    +EK+Y    L R+VIDE+HC S+  HDFR DYK L  LK  YP +P+LGLTATA   VI D+K  L L+++CL+ K ++NR N+FYEV+        F+S        I +LI  RF G SGI++CF++KD E +  E+ + GI A+ Y+  +  + +  +H  W     +V+VAT AFGMGIDK NVRFVIH S SKS+ENYYQESGRAGRD KR+ CI+F++  + F+  + +FTE++G+ NL  + RY      C+R  +     E +    CK MC  C+  + E    ++ D+ + A  ++K +E+ K    ++T  K++     + ++         P +      ++   HLV+ G L+ ++ F  +S  +Y++ G+
Sbjct:    9 EISEELQDIEVQIESLLERQQFLLSRKQELEVIALSNSNDSVLLSFSSNVACAQGSDWSSTAFSWSQEVEAALKNVFKIDTFRHLQLECINATMSGVDCILIMPTGGGKSLCFQLPAVVSKGLTLVVSPLVSLMEDQLWALKRLGIKAALLNASSTREEVNSVHASIVDKKSD---LKMLYVTPEKIAKSKRFMAKLEKSYESGLLSRIVIDEVHCTSQWGHDFRPDYKILGILKRQYPGVPILGLTATATTKVIEDVKKILGLHANCLLLKASFNRPNLFYEVQSKPTTNSAFMST-------IHQLITKRFSGDSGIIYCFSRKDAEQVAIEMSSRGIKAACYHADMPPESRSQVHMAWTTNKLQVVVATVAFGMGIDKSNVRFVIHHSFSKSMENYYQESGRAGRDEKRASCIVFYRPFDIFRHSTMVFTEQTGLQNLYGIVRYCQQQGVCRRTLIGRHFGEGWDPAQCKQMCDNCSRRDDERGLNELHDITQYASDLLKILEQAKAAGDRVTANKLVDAWCGRGAVSLRVRGVSAPSLTPSE-CERVVVHLVVEGVLREEFHFTPYSTISYIVKGA 577

[Close]

BLAST of ATP-dependent DNA helicase vs. Ensembl Nematostella
Match: EDO34091 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SQC9])

HSP 1 Score: 226.868 bits (577), Expect = 4.651e-67
Identity = 127/359 (35.38%), Postives = 202/359 (56.27%), Query Frame = 1

Query:  265 SSNIKKLLQDKFKIKNFKS-LQLKTINATLDKLDCIFISSP-GSGKSLCYQLASMIS-GFTLVIAPLGSLIQDQMIVSEKFGISCISLDSNSSVKIQNEIFKAMETDPVDNVTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRLVIDEIHCCSELSHDFRQDYKNLHGLKSLYPNLPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEVKFLSNEKKEGEEICKLIKSRFDGQ-------SGIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNENCKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFWKLAE 1311
            ++++KK L++ FK + FKS LQ +        L  +F+S P GSGKSLCYQL ++++ G T+V +PL +LIQDQ+       I+  +L+S      ++E  + M+       T KL+Y TP+ ++ +    K ++  Y  K L    +DE HC S+  HDFR DY  L  L++ Y ++  + LTATA + V  DI T L++ S+  V K    R N++Y++ F    +    ++ +   +  + +       SGI++C  +  C+ + + L   G+ A  Y+  L  D +  +  +W+     VI AT +FGMG+DK +VRFV H S+ +S+E YYQESGRAGRDG+ S C L++  AE
Sbjct:    2 ATDLKKTLRNVFKFREFKSELQQRACETVSKGLQDVFVSMPTGSGKSLCYQLPAVVAPGITIVFSPLIALIQDQVTYLRTLKITVETLNSKLP---ESERKRVMKDLYFVKPTVKLLYITPE-LAATPGFQKVLDSLYKRKLLSLFAVDEAHCVSQWGHDFRPDYLRLGKLRNKYKDVAWVALTATATSRVKEDILTALHMQSNVAVFKSQCYRPNLYYDISFKELLEDPYADLKQFADAALEDEDSGEAKGSGIIYCRTRDACQEVASRLSRKGLSAKPYHAGLKSDKRDKVQQEWMEGKVAVICATISFGMGVDKGDVRFVAHWSLPQSMEGYYQESGRAGRDGQPSYCRLYYSRAE 356

[Close]

BLAST of ATP-dependent DNA helicase vs. Ensembl Nematostella
Match: EDO25520 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A8DW89])

HSP 1 Score: 162.54 bits (410), Expect = 3.985e-44
Identity = 87/235 (37.02%), Postives = 134/235 (57.02%), Query Frame = 1

Query:  595 YKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRLVIDEIHCCSELSHDFRQDYKNLHGLKSLYPNLPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEVKFLSNEKKEGEEICKLIKSRFDGQSGIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNENCKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFW 1299
            Y+L+Y +P+++      T+  E+      +  + +DE HC S+  HDFR DY  +  LK ++   PVL +TA+A N V  DI   L L +  L  K    R NI Y + +  +E+K+ + +  L  ++    S I++C ++K  E + N L+ NG  +  Y+  L   ++++  N WLN N + IVAT AFGMGIDKP+VR V++  + + LE YYQESGRAGRD   +  IL +
Sbjct:   39 YELLYISPERLQ-----TRLFEEYLPALNINLIAVDEAHCISQWGHDFRPDYLKIAQLKQVFARTPVLAVTASATNEVKQDIARQLQLKTPTLYQK-GIERKNIHYTIHY--SERKDNDLLEALGNNK---GSKIIYCRSRKTTERINNLLLQNGYSSVVYHAGLDKKVRENAQNDWLNNNTETIVATTAFGMGIDKPDVRLVVNYDLPEHLEAYYQESGRAGRDELPAKSILLY 262

[Close]

BLAST of ATP-dependent DNA helicase vs. Ensembl Nematostella
Match: EDO32537 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SUT5])

HSP 1 Score: 139.813 bits (351), Expect = 1.860e-34
Identity = 111/396 (28.03%), Postives = 186/396 (46.97%), Query Frame = 1

Query:  349 LDKLDCIFISSPGSGKSLCYQLASMI-----SGFTLVIAPLGSLIQDQMIVSEKFGISCISLDSNSSVKIQNEIFKAMETDPVDNVTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRLVIDEIHCCSELSHDFRQDYKNLHG-LKSLYPNLPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEVKFLSNEKKEGEEICKLIKS-RFDG-QSGIVFCFNQKDCENLTNEL---------------VNNGILASSYYGTLGYDIKKDIHNKWLNENCKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFWKLAEYFKIGSNIFTEKSGIPNLNIMNRYILDDCTCKRVSLSSILDEKFTVNDCKNM 1467
            L  +  + + S G+GKSLCYQL + +        TLVI+PL SL++DQ I    FG+    L +N +   + +I     TD        L+ +    +      +  +  +     +    IDE HC SE SH+FR  Y  +   L+  Y     LGLTATA  S  + +   L +     V +      N+   V   S ++ + + + +L++  RF   +S I++C  ++  E +   +               V +G  A SY+  +    ++ +  ++++   + + AT AFGMG+DK +VR +IH +M KS E+Y QE GRAGRDGK S C              ++F ++ G  +L  + R+I  + T  RV++  +++  F   DCK +
Sbjct:    4 LSGMSSLVVLSTGAGKSLCYQLPAYMYHKRSPCLTLVISPLVSLMEDQ-ITGLPFGLKGACLHNNQTKPQRLKIL----TDITAGKVAVLLVSPEALVGGGMGGSGCLPSSTKMPPIAFACIDEAHCLSEWSHNFRPSYLRVCKILRDRYGVQCFLGLTATATQSTADSVAQHLGIADAGAVIRGAAVPPNLRLSV---SRDRDKDKALIELLQGPRFSRCESIIIYCTRREVTERVATLIRTCMQHMQPTIRHDDVISGSDAESYHAGMSAAQRRKVQKRFMSGELRAVAATVAFGMGLDKSDVRAIIHYNMPKSFESYVQEIGRAGRDGKPSHC--------------HVFLDREG-QDLCELRRHIFSN-TVDRVTVKRLVNRIFPRCDCKKL 375

[Close]

BLAST of ATP-dependent DNA helicase vs. Ensembl Nematostella
Match: EDO33287 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SSN3])

HSP 1 Score: 120.553 bits (301), Expect = 1.872e-31
Identity = 66/179 (36.87%), Postives = 104/179 (58.10%), Query Frame = 1

Query:  787 LPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEVKFLSNEKKEGEE---ICKLIKSRFDGQSGIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNENCKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFWKLAEY 1314
            +P++ LTATA   V  DI  +L L +  +V    ++R N+++EV    +   E      I  + K  F G + I++C  +K  E + + L  NGIL  +Y+  +    +K  H+K++ +  + +VAT AFGMGIDKP+VR +IH    K +E+Y QE GRAGRDG+ S C +F+K  ++
Sbjct:    1 MPIVALTATATPDVRRDICLSLKLKTPSVVCT-GFDRPNLYFEVHKKGDSVMEDLRPLLISDINKFSFAGPT-IIYCPTKKTTEMIADALKANGILCEAYHAGMALKKRKSAHHKFIRDEIQCVVATVAFGMGIDKPDVRQIIHYGAPKDIESYSQEIGRAGRDGEPSSCYVFYKPGDF 177

[Close]

BLAST of ATP-dependent DNA helicase vs. Ensembl Medaka
Match: recql (RecQ like helicase [Source:NCBI gene;Acc:101164117])

HSP 1 Score: 361.303 bits (926), Expect = 2.729e-113
Identity = 203/571 (35.55%), Postives = 324/571 (56.74%), Query Frame = 1

Query:  235 KDYGKENFPWSSNIKKLLQDKFKIKNFKSLQLKTINATLDKLDCIFISSPGSGKSLCYQLASMIS-GFTLVIAPLGSLIQDQMIVSEKFGISCISLDSNSSVKIQNEIFKAMETDPVDNVTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRLVIDEIHCCSELSHDFRQDYKNLHGLKSLYPNLPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEVKF-LSNEKKEGEEICKLIKSRFDGQSGIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNENCKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFWKLAEYFKIGSNIFTEKSGIPNLNIMNRYILDDCTCKRVSLSSILDEKFTVNDCKNMCSVCADTESEMSSIDIADVYKSALTIIKNIE--KTKNPKITGKKIISELANQMSLYFADLANRFPGIDYKLF---------LDKAFCHLVLVGYLKLDYSFGSFSNFTYVIAGSKT-LKSNEKIDIPIRIAKSDKMRNLVQNVKQNESSNVKKSYLKR 1905
            + Y +  FPWS+ + + L+  F +  F+ LQL+ IN T++  D   +   G GKSLCYQL ++ S GFTLV++PL SL++DQ+++     +   +L+++S  +    +  A+ TDP     +KL+Y TP+KI+ SK L   +EKAY  K L R+ +DE+HCCS+  HDFR DYK L  LK  +P++P+LGLTATA +SV+ D +  L +     +   ++NR+N++YEV+   S+      +I  LIK+R+  QSGIV+ F+QKD E++++ L  +GI A  Y+  +  + K  +H KW +   +V+VAT AFGMGIDKP+VRFVIH ++SKS+ENYYQESGRAGRD + +DCI+++  A+ F+I + +  E  G   L  M  +  +   C+R  ++   DE +   DC  MC  C       +  +  DV + A  +++ +E   + + ++T  K++                R P    K+           +     L+L GYL+ D+SF  ++ + YV  G +  L  N+   + +++  S      V ++   ESS VK  + K+
Sbjct:   79 QRYDEAEFPWSAAVDQHLRTSFHLSAFRPLQLRAINLTMEGRDVFLVMPTGRGKSLCYQLPAVCSEGFTLVVSPLVSLMEDQLLLLRSLQVPAAALNASSGKEHTKTVLAAL-TDP--KAPFKLVYVTPEKIAKSKLLMSRLEKAYKAKLLSRMAVDEVHCCSQWGHDFRPDYKLLGILKRQFPSVPLLGLTATATSSVLQDCRKILCVPQPVTL-TASFNRANLYYEVRVKDSDSDLSLSDISSLIKNRYKEQSGIVYVFSQKDAESVSSALQKSGIQAYPYHANMDPEDKSRVHRKWTSNKIQVVVATVAFGMGIDKPDVRFVIHHTISKSIENYYQESGRAGRDDRPADCIVYFGFADIFRISTMVVMESVGQKKLLQMVDFCQNVDRCRRSLMAVHFDEVWDDEDCNQMCDTCRHP----AGYNTLDVTQHARQVVQIVELATSMDERLTPLKLVEA-----------WRGRGPAKRRKMIQTTELPRRQAEAVIVFLLLQGYLREDFSFTPYTTYFYVKLGRRAPLLKNQAHSLTMKMKMSGA--EPVSDLSAAESSEVKGPHAKQ 628

[Close]

Query:  235 KDYGKENFPWSSNIKKLLQDKFKIKNFKSLQLKTINATLDKLDCIFISSPGSGKSLCYQLASMIS-GFTLVIAPLGSLIQDQMIVSEKFGISCISLDSNSSVKIQNEIFKAMETDPVDNVTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRLVIDEIHCCSELSHDFRQDYKNLHGLKSLYPNLPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEVKF-LSNEKKEGEEICKLIKSRFDGQSGIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNENCKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFWKLAEYFKIGSNIFTEKSGIPNLNIMNRYILDDCTCKRVSLSSILDEKFTVNDCKNMCSVCADTESEMSSIDIADVYKSALTIIKNIE--KTKNPKITGKKIISELANQMSLYFADLANRFPGIDYKLF---------LDKAFCHLVLVGYLKLDYSFGSFSNFTYVIAGSKT-LKSNEKIDIPIRIAKSDKMRNLVQNVKQNESSNVKKSYLKR 1905
            + Y +  FPWS+ + + L+  F +  F+ LQL+ IN T++  D   +   G GKSLCYQL ++ S GFTLV++PL SL++DQ+++     +   +L+++S  +    +  A+ TDP     +KL+Y TP+KI+ SK L   +EKAY  K L R+ +DE+HCCS+  HDFR DYK L  LK  +P++P+LGLTATA +SV+ D +  L +     +   ++NR+N++YEV+   S+      +I  LIK+R+  QSGIV+ F+QKD E++++ L  +GI A  Y+  +  + K  +H KW +   +V+VAT AFGMGIDKP+VRFVIH ++SKS+ENYYQESGRAGRD + +DCI+++  A+ F+I + +  E  G   L  M  +  +   C+R  ++   DE +   DC  MC  C       +  +  DV + A  +++ +E   + + ++T  K++                R P    K+           +     L+L GYL+ D+SF  ++ + YV  G +  L  N+   + +++  S      V ++   ESS VK  + K+
Sbjct:   79 QRYDEAEFPWSAAVDQHLRTSFHLSAFRPLQLRAINLTMEGRDVFLVMPTGRGKSLCYQLPAVCSEGFTLVVSPLVSLMEDQLLLLRSLQVPAAALNASSGKEHTKTVLAAL-TDP--KAPFKLVYVTPEKIAKSKLLMSRLEKAYKAKLLSRMAVDEVHCCSQWGHDFRPDYKLLGILKRQFPSVPLLGLTATATSSVLQDCRKILCVPQPVTL-TASFNRANLYYEVRVKDSDSDLSLSDISSLIKNRYKEQSGIVYVFSQKDAESVSSALQKSGIQAYPYHANMDPEDKSRVHRKWTSNKIQVVVATVAFGMGIDKPDVRFVIHHTISKSIENYYQESGRAGRDDRPADCIVYFGFADIFRISTMVVMESVGQKKLLQMVDFCQNVDRCRRSLMAVHFDEVWDDEDCNQMCDTCRHP----AGYNTLDVTQHARQVVQIVELATSMDERLTPLKLVEA-----------WRGRGPAKRRKMIQTTELPRRQAEAVIVFLLLQGYLREDFSFTPYTTYFYVKLGRRAPLLKNQAHSLTMKMKMSGA--EPVSDLSAAESSEVKGPHAKQ 628

[Close]

Query:  235 KDYGKENFPWSSNIKKLLQDKFKIKNFKSLQLKTINATLDKLDCIFISSPGSGKSLCYQLASMIS-GFTLVIAPLGSLIQDQMIVSEKFGISCISLDSNSSVKIQNEIFKAMETDPVDNVTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRLVIDEIHCCSELSHDFRQDYKNLHGLKSLYPNLPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEVKF-LSNEKKEGEEICKLIKSRFDGQSGIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNENCKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFWKLAEYFKIGSNIFTEKSGIPNLNIMNRYILDDCTCKRVSLSSILDEKFTVNDCKNMCSVCADTESEMSSIDIADVYKSALTIIKNIE--KTKNPKITGKKIISELANQMSLYFADLANRFPGIDYKLF---------LDKAFCHLVLVGYLKLDYSFGSFSNFTYVIAGSKT-LKSNEKIDIPIRIAKSDKMRNLVQNVKQNESSNVKKSYLKR 1905
            + Y +  FPWS+ + + L+  F +  F+ LQL+ IN T++  D   +   G GKSLCYQL ++ S GFTLV++PL SL++DQ+++     +   +L+++S  +    +  A+ TDP     +KL+Y TP+KI+ SK L   +EKAY  K L R+ +DE+HCCS+  HDFR DYK L  LK  +P++P+LGLTATA +SV+ D +  L +     +   ++NR+N++YEV+   S+      +I  LIK+R+  QSGIV+ F+QKD E++++ L  +GI A  Y+  +  + K  +H KW +   +V+VAT AFGMGIDKP+VRFVIH ++SKS+ENYYQESGRAGRD + +DCI+++  A+ F+I + +  E  G   L  M  +  +   C+R  ++   DE +   DC  MC  C       +  +  DV + A  +++ +E   + + ++T  K++                R P    K+           +     L+L GYL+ D+SF  ++ + YV  G +  L  N+   + +++  S      V ++   ESS VK  + K+
Sbjct:   79 QRYDEAEFPWSAAVDQHLRTSFHLSAFRPLQLRAINLTMEGRDVFLVMPTGRGKSLCYQLPAVCSEGFTLVVSPLVSLMEDQLLLLRSLQVPAAALNASSGKEHTKTVLAAL-TDP--KAPFKLVYVTPEKIAKSKLLMSRLEKAYKAKLLSRMAVDEVHCCSQWGHDFRPDYKLLGILKRQFPSVPLLGLTATATSSVLQDCRKILCVPQPVTL-TASFNRANLYYEVRVKDSDSDLSLSDISSLIKNRYKEQSGIVYVFSQKDAESVSSALQKSGIQAYPYHANMDPEDKSRVHRKWTSNKIQVVVATVAFGMGIDKPDVRFVIHHTISKSIENYYQESGRAGRDDRPADCIVYFGFADIFRISTMVVMESVGQKKLLQMVDFCQNVDRCRRSLMAVHFDEVWDDEDCNQMCDTCRHP----AGYNTLDVTQHARQVVQIVELATSMDERLTPLKLVEA-----------WRGRGPAKRRKMIQTTELPRRQAEAVIVFLLLQGYLREDFSFTPYTTYFYVKLGRRAPLLKNQAHSLTMKMKMSGA--EPVSDLSAAESSEVKGPHAKQ 628

[Close]

BLAST of ATP-dependent DNA helicase vs. Ensembl Medaka
Match: recql (RecQ like helicase [Source:NCBI gene;Acc:101164117])

HSP 1 Score: 348.977 bits (894), Expect = 3.932e-110
Identity = 192/558 (34.41%), Postives = 301/558 (53.94%), Query Frame = 1

Query:  235 KDYGKENFPWSSNIKKLLQDKFKIKNFKSLQLKTINATLDKLDCIFISSPGSGKSLCYQLASMIS-GFTLVIAPLGSLIQDQMIVSEKFGISCISLDSNSSVKIQNEIFKAMETDPVDNVTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRLVIDEIHCCSELSHDFRQDYKNLHGLKSLYPNLPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEVKFLSNEKKEGEEICK------------------------------LIKSRFDGQSGIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNENCKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFWKLAEYFKIGSNIFTEKSGIPNLNIMNRYILDDCTCKRVSLSSILDEKFTVNDCKNMCSVCADTESEMSSIDIADVYKSALTIIKNIE--KTKNPKITGKKIISELANQMSLYFADLANRFPGIDYKLF---------LDKAFCHLVLVGYLKLDYSFGSFSNFTYVIAGSKT 1782
            + Y +  FPWS+ + + L+  F +  F+ LQL+ IN T++  D   +   G GKSLCYQL ++ S GFTLV++PL SL++DQ+++     +   +L+++S  +    +  A+ TDP     +KL+Y TP+KI+ SK L   +EKAY  K L R+ +DE+HCCS+  HDFR DYK L  LK  +P++P+LGLTATA +SV+ D +  L +     +   ++NR+N++YEV             C                               LIK+R+  QSGIV+ F+QKD E++++ L  +GI A  Y+  +  + K  +H KW +   +V+VAT AFGMGIDKP+VRFVIH ++SKS+ENYYQESGRAGRD + +DCI+++  A+ F+I + +  E  G   L  M  +  +   C+R  ++   DE +   DC  MC  C       +  +  DV + A  +++ +E   + + ++T  K++                R P    K+           +     L+L GYL+ D+SF  ++ + YV  G + 
Sbjct:   79 QRYDEAEFPWSAAVDQHLRTSFHLSAFRPLQLRAINLTMEGRDVFLVMPTGRGKSLCYQLPAVCSEGFTLVVSPLVSLMEDQLLLLRSLQVPAAALNASSGKEHTKTVLAAL-TDP--KAPFKLVYVTPEKIAKSKLLMSRLEKAYKAKLLSRMAVDEVHCCSQWGHDFRPDYKLLGILKRQFPSVPLLGLTATATSSVLQDCRKILCVPQPVTL-TASFNRANLYYEVSGPRTHIHTHTHTCSAGIRAHQQDFPAQVRVKDSDSDLSLSDISSLIKNRYKEQSGIVYVFSQKDAESVSSALQKSGIQAYPYHANMDPEDKSRVHRKWTSNKIQVVVATVAFGMGIDKPDVRFVIHHTISKSIENYYQESGRAGRDDRPADCIVYFGFADIFRISTMVVMESVGQKKLLQMVDFCQNVDRCRRSLMAVHFDEVWDDEDCNQMCDTCRHP----AGYNTLDVTQHARQVVQIVELATSMDERLTPLKLVEA-----------WRGRGPAKRRKMIQTTELPRRQAEAVIVFLLLQGYLREDFSFTPYTTYFYVKLGRRA 617

[Close]

BLAST of ATP-dependent DNA helicase vs. Ensembl Medaka
Match: blm (BLM RecQ like helicase [Source:NCBI gene;Acc:100049173])

HSP 1 Score: 284.263 bits (726), Expect = 1.117e-81
Identity = 189/539 (35.06%), Postives = 279/539 (51.76%), Query Frame = 1

Query:  253 NFPWSSNIKKLLQDKFKIKNFKSLQLKTINATLDKLDCIFISSPGSGKSLCYQLASMIS-GFTLVIAPLGSLIQDQMIVSEKFGISCISLDSNSSVKIQNEIFKAM-ETDPVDNVTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRLVIDEIHCCSELSHDFRQDYKNLHGLKSLYPNLPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEVKFLSNEKKEGEEICKLIKSRFDGQSGIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNEN-CKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFWKLAEYFKIGSNIFTEKSG--------IPNLNIMNRYILDDCTCKRVSLSSILDE-KFTVNDCKNMCSVCADTESEMSSIDIADVYKSALTIIKNIEKTKNPKITGKKIISELANQMSLYFADLANRFPG-----IDYKLF----------LDKAFCHLVLVGYLKLD-YSFGSFSNFTYVIAGSKTL 1785
            NFP S  + K+   +F +  F+  QL+ INA L   D   +   G GKSLCYQL + +S G T+V++PL SLI DQ+       I   SL  + S      I+  +   DP+     KL+Y TP+K+S S +L  A++  Y    L R +IDE HC S+  HDFR D+K LH L+  +P++ ++ LTATA   V  DI   LN+     V   ++NRSN+ Y V      KK  E+    IK  +   SGIV+C ++ DC+ +   L   GI A SY+  L    ++ + +KW+N++ C+VI AT AFGMGIDKP+VR+VIH S+ KS+E YYQESGRAGRDG+ S CILF+   +  +I   I  ++ G          NL+ M  +  +   C+R+ L +   E  F  N CK+   V  D  ++ +   + +V +    I++ ++  +N +  G +   + A Q  L    L + F G     I   +F           D+ F  LVL   L  D Y   +    +Y+ AG K +
Sbjct:  597 NFPHSQEMMKIFHKRFGLHQFRFNQLEAINAALLGEDAFVLMPTGGGKSLCYQLPACVSPGVTVVVSPLKSLIVDQIQKLTTLDIPATSLSGDKSDSEAGRIYMQLSRKDPL----IKLLYVTPEKVSASGRLISALQNLYERGLLARFIIDEAHCVSQWGHDFRPDFKRLHELRQKFPSVRMMALTATATPRVQKDILNQLNMMRP-QVFTMSFNRSNLKYSV-LPKKPKKVDEDCIGWIKKHYPRDSGIVYCLSRNDCDAMAESLKRAGIQALSYHAGLSDGDREYVQSKWINQDGCQVICATIAFGMGIDKPDVRYVIHASLPKSVEGYYQESGRAGRDGEISHCILFYSYTDVHRIKRIISMDREGDSHTKATHFNNLHSMVHFCENVMECRRIQLLAYFGELNFNRNFCKDHPDVSCDNCAKPNQYQMKNVTEDVKKIVRFVQ--ENCEKVGSR-FGKTAQQNRLTLNMLVDIFIGSKSAKIQTGMFGMGGAYSRHNADRLFKKLVLENILVEDLYITNNGQAVSYISAGPKAM 1126

[Close]

BLAST of ATP-dependent DNA helicase vs. Planmine SMEST
Match: SMESG000064966.1 (SMESG000064966.1)

HSP 1 Score: 1227.62 bits (3175), Expect = 0.000e+0
Identity = 607/616 (98.54%), Postives = 611/616 (99.19%), Query Frame = 1

Query:  109 EIDKRIVAIDNEIKTLTHEKEDLIKKKKQLSISTKGHSITSNKDYGKENFPWSSNIKKLLQDKFKIKNFKSLQLKTINATLDKLDCIFISSPGSGKSLCYQLASMISGFTLVIAPLGSLIQDQMIVSEKFGISCISLDSNSSVKIQNEIFKAMETDPVDNVTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRLVIDEIHCCSELSHDFRQDYKNLHGLKSLYPNLPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEVKFLSNEKKEGEEICKLIKSRFDGQSGIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNENCKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFWKLAEYFKIGSNIFTEKSGIPNLNIMNRYILDDCTCKRVSLSSILDEKFTVNDCKNMCSVCADTESEMSSIDIADVYKSALTIIKNIEKTKNPKITGKKIISELANQMSLYFADLANRFPGIDYKLFLDKAFCHLVLVGYLKLDYSFGSFSNFTYVIAGSKTLKSNEKIDIPIRIAKSDKMRNLVQNVKQNESSNVKKSYLKRLFKGSNDDIVETKILKR 1956
            EIDKRIVAIDNEIKTLTHEKE+LIKKKKQLS  TKGHSITSNKDYGKENFPWSSNIKKLLQDKFKIKNFKSLQLKTINATLDKLDCIFISSPGSGKSLCYQLASMISGFTLVIAPLGSLIQDQMIVSEKFGISCISLDSNSSVKIQNEIFKAMETDPVDNVTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRLVIDEIHCCSELSHDFRQDYKNLHGLKSLYPNLPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEVKFLSNEKKEGEEICKLIKSRFDGQSGIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNENCKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFWKLAEYFKIGSNIFTEKSGIPNLNIMNRYILDDCTCKRVSLSSILDEKFTVNDCKNMCSVCADTESEMSSIDIADVYKSALTIIKNIEKTKNPKITG K+ISELANQMSLY ADLA+RFPGIDYKLFLDKAFCHLVL GYLKLDYSFGSFSNFTYVIAGSKTLKSNEKIDIPIRI+KSDKMRNLVQNVKQNESSNVKKSYLKRLFKGSNDDIVETKILKR
Sbjct:    6 EIDKRIVAIDNEIKTLTHEKENLIKKKKQLS--TKGHSITSNKDYGKENFPWSSNIKKLLQDKFKIKNFKSLQLKTINATLDKLDCIFISSPGSGKSLCYQLASMISGFTLVIAPLGSLIQDQMIVSEKFGISCISLDSNSSVKIQNEIFKAMETDPVDNVTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRLVIDEIHCCSELSHDFRQDYKNLHGLKSLYPNLPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEVKFLSNEKKEGEEICKLIKSRFDGQSGIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNENCKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFWKLAEYFKIGSNIFTEKSGIPNLNIMNRYILDDCTCKRVSLSSILDEKFTVNDCKNMCSVCADTESEMSSIDIADVYKSALTIIKNIEKTKNPKITGNKMISELANQMSLYCADLASRFPGIDYKLFLDKAFCHLVLAGYLKLDYSFGSFSNFTYVIAGSKTLKSNEKIDIPIRISKSDKMRNLVQNVKQNESSNVKKSYLKRLFKGSNDDIVETKILKR 619

[Close]

BLAST of ATP-dependent DNA helicase vs. Planmine SMEST
Match: SMESG000064967.1 (SMESG000064967.1)

HSP 1 Score: 452.21 bits (1162), Expect = 1.101e-154
Identity = 208/340 (61.18%), Postives = 266/340 (78.24%), Query Frame = 1

Query:  178 IKKKKQLSISTKGHSITSNKDYGKENFPWSSNIKKLLQDKFKIKNFKSLQLKTINATLDKLDCIFISSPGSGKSLCYQLASMISGFTLVIAPLGSLIQDQMIVSEKFGISCISLDSNSSVKIQNEIFKAMETDPVDNVTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRLVIDEIHCCSELSHDFRQDYKNLHGLKSLYPNLPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEVKFLSNEKKEGEEICKLIKSRFDGQSGIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNENCKVIVATNAFGMGIDKPNVR 1197
            +KKK+ L    K   +  N DY  ++FPWS  + K+LQ+ FK+  F++LQLKTIN TL K DCI I   G GKSLCYQL S+++G T+ ++PL SL+QDQ+++S++FGI  +SLD+N  VK+QNE++K+M++DPVD + YKLI+ TP+KIS SKKL KAIEK+Y D R+ R+VIDEIHCCS+  HDFR DYK LH  KSL+P +P+LGLTATA +S+I+DIK  L LN+DCLV++D YNR N+FY VKFLSN+ K+ +EICKLIKSR+ GQSGIV+CF QKDCE LTNELV NGI A  Y+    Y+ +KD+H+KWLNE C VIVAT AFGMGIDKPNVR
Sbjct:    1 MKKKQALEQHIKSAFVNDNTDYENDSFPWSLTVNKILQEVFKMDKFRALQLKTINTTLSKRDCILIKPTGGGKSLCYQLPSLLTGLTIAVSPLVSLMQDQLLISQRFGIPSVSLDANCPVKLQNEVYKSMQSDPVDKLKYKLIFVTPEKISKSKKLMKAIEKSYADNRISRIVIDEIHCCSQWGHDFRPDYKGLHIFKSLFPKIPILGLTATATDSIIDDIKEILGLNADCLVYRDVYNRPNLFYNVKFLSNDDKDDKEICKLIKSRYLGQSGIVYCFTQKDCETLTNELVLNGINACFYHANTSYEYRKDVHSKWLNEECNVIVATIAFGMGIDKPNVR 340

[Close]

BLAST of ATP-dependent DNA helicase vs. Planmine SMEST
Match: SMESG000060148.1 (SMESG000060148.1)

HSP 1 Score: 275.018 bits (702), Expect = 1.159e-79
Identity = 177/570 (31.05%), Postives = 291/570 (51.05%), Query Frame = 1

Query:  253 NFPWSSNIKKLLQDKFKIKNFKSLQLKTINATLDKLDCIFISSPGSGKSLCYQLASMIS-GFTLVIAPLGSLIQDQMIVSEKFGISCISLDSNSSVKIQNEIFKAMETDPVDNVTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRLVIDEIHCCSELSHDFRQDYKNLHGLKSLYPNLPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEVKFLSNEKKEGEEICKLIKSRFDGQSGIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNEN-CKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFWKLAEYFKIGSNIFTEKSGI--------PNLNIMNRYILDDCTCKRVSLSSILDEKFTVNDCKN----MCSVCADT-ESEMSSIDIADVYKSALTIIKNI----------------EKTKNPKITGKKIISE-LANQMSLYFADLANRFPGIDYKLFLDKAFCHLVLVGYL--KLDYSFGSFSNFTYVIAGSK---TLKSNEKIDIPIRIAKSDKMRNLV 1851
            +FP +  +    ++ F +  F+  Q + IN+TL+  D   I   G GKSLCYQL ++I+ G T+VI+PL SLI DQ+   ++  I    L  +      ++I   +++     +  KL+Y TP+K+  S+KL    +     K L R VIDE HC S+  HDFR  Y+ L  L++ +PN+P++ LTATA   V  DI   L + ++      ++NR N+ +E++     KK   EI  L+ ++F  QSGIV+C ++ +C+ + + +  +G+   +Y+  +    +K +   W+NEN CK++VAT AFGMGIDKP+VRFV+H S+ KS+E +YQE+GRAGRDG  + C+LF+   +  ++   I+++ SG           L +M  Y  +   C+R  + +   E F    C      +C  C ++ ++++   D+ D  K+ +  +  I                    N KI  K+  +  L    S++  + A RF            F HLV  GYL  K+  +   F    +V+ G K    L  N  + +PI   ++ K ++ V
Sbjct:  309 DFPHTERMMIAFKEVFGLNGFRRNQKEAINSTLNGFDTFVIMPTGGGKSLCYQLPAVITEGVTIVISPLKSLIHDQVTKLQELDIVATHLSGDLKEAEVDKILLQLQSQ---FMQIKLLYVTPEKVVESRKLMNVFQSLNQRKLLSRFVIDEAHCVSQWGHDFRPHYRLLGVLRTTFPNVPMIALTATATTKVREDILYQLKMKNNTKWFIQSFNRGNLRWEIR-PKTAKKCISEIINLVNAKFRDQSGIVYCLSRNECDEVASVMAQSGLKCQAYHAGMSDTKRKQVQEMWINENGCKIVVATIAFGMGIDKPDVRFVVHYSIPKSIEGFYQETGRAGRDGLPATCVLFYSWTDVVRMRKLIYSDNSGTVETKKQHEQQLFLMVSYCENLIDCRRTQVLNHFGEHFDRKLCGAVKGCICDNCQNSNDNKVVMRDLTDHAKAVVKYVMEISNVGWGSTLNYVLDVFRGANNAKIVEKQGANNWLYGTGSVFSKNDAERF------------FHHLVFEGYLWEKMVVTQADFV-VAHVVPGPKHQLLLSGNATVQMPISKPRTTKDKDKV 861

[Close]

BLAST of ATP-dependent DNA helicase vs. Planmine SMEST
Match: SMESG000028029.1 (SMESG000028029.1)

HSP 1 Score: 209.92 bits (533), Expect = 2.669e-57
Identity = 151/425 (35.53%), Postives = 225/425 (52.94%), Query Frame = 1

Query:  283 LLQDKFKIKNFKS-LQLKTINATLDKLDCIFISSP-GSGKSLCYQLASMI--SGFTLVIAPLGSLIQDQMIVSEKFGISCISLDSNSSVKIQNEIFKAMETDPV--DNVTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVR-LVIDEIHCCSELSHDFRQDYKNLHGLKS-LYPNLPVLGLTATANNSVINDIKTTLNLNSDCLVHKDNYNRSNIFYEVKF---LSNEKKE-GEEICKLIKSRF-------DGQSGIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNENCKVIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCILFWKLAEYFKIGSNIFTEKS-----GIPNLNIMNRYILDDCTCKRVSLSSILDEKFTVNDCKNMCSVCAD 1485
            +L+  F+   FKS LQ + I   +   + +FIS P GSGKSLCYQ  ++   +G +++I+PL +LI DQ++   K  I   +++S S V  +NE+   + T     D    +L+Y TP++   S    + I K+   K L+   VIDE HC SE  HDFR DY  L  L+S L  N+P + LTATAN  V  DI   LN  +        + R NIFY+VKF   L++ K+   + I K +           D  S IV+C  ++ CE +   L + G+ A  Y+  +   I+++I   W+N    ++ AT +FGMG+DK NVR V H ++ KSL  YYQESGRAGRDGK S   +++  +E   I   I  +K          L IM  YI +   C+ + ++   +++FT   CK +C  C +
Sbjct:    9 VLKHTFQFDEFKSPLQKEAIENIIHSKNDVFISMPTGSGKSLCYQFPAVYFETGVSIIISPLLALIHDQILHLSKRNICARTINSKSKVDERNEVISDLTTFNCFKDATKIRLLYVTPEQCQTS--TFQNIAKSLSKKNLLNYFVIDEAHCLSEWGHDFRPDYLKLGQLRSTLLNNIPCIALTATANKKVSEDIIKCLNFKNHKTFRMPVF-RDNIFYDVKFTDLLTDSKRHIFDFIFKCLGCPTSNNCNWNDIGSCIVYCRKREHCEEMALLLTSYGLQAKPYHAGIKQSIREEIQLDWINGKFPIVAATISFGMGVDKSNVRVVCHWTIPKSLTAYYQESGRAGRDGKLSYSRIYYDPSETNTITFLINKQKEKERVKANAWLQIMRDYI-EIPKCRHLRIAEHFNDEFTA--CKTLCDFCTN 427

[Close]

BLAST of ATP-dependent DNA helicase vs. Planmine SMEST
Match: SMESG000064968.1 (SMESG000064968.1)

HSP 1 Score: 172.555 bits (436), Expect = 5.736e-50
Identity = 88/148 (59.46%), Postives = 112/148 (75.68%), Query Frame = 1

Query: 1465 MCSVCADTESEMSSIDIADVYKSALTIIKNIEKTKNPKITGKKIISELANQMSLYFADLANRFPG-IDYKLFLDKAFCHLVLVGYLKLDYSFGSFSNFTYVIAGSKTLKSNEKIDIPIRIAKSDKMRNLVQNVKQNESSNVKKSYLKR 1905
            MCS+C DTES MS +DI DV KSAL II N++K+KNP ITG K++ ELANQM+LY  DL NRFPG ID KLF DKA C+L+  GYLKL++ FGSF+N+TY+++G KTL S EKI+  IRI  SD   NL +N + ++S  ++KS LKR
Sbjct:    1 MCSICTDTESTMSPVDITDVCKSALAIIDNVKKSKNPNITGNKLVGELANQMNLYSTDLINRFPGIIDIKLFFDKAICYLIHEGYLKLNFHFGSFTNYTYIVSGKKTLASEEKINFSIRIPISDLKINL-ENSEVSKSGKLEKSSLKR 147

The following BLAST results are available for this feature:

BLAST of ATP-dependent DNA helicase vs. Ensembl Human
BLAST of ATP-dependent DNA helicase vs. Ensembl Celegans
BLAST of ATP-dependent DNA helicase vs. Ensembl Fly
BLAST of ATP-dependent DNA helicase vs. Ensembl Zebrafish
BLAST of ATP-dependent DNA helicase vs. Ensembl Xenopus
BLAST of ATP-dependent DNA helicase vs. Ensembl Mouse
BLAST of ATP-dependent DNA helicase vs. UniProt/SwissProt
BLAST of ATP-dependent DNA helicase vs. TrEMBL
BLAST of ATP-dependent DNA helicase vs. Ensembl Cavefish
BLAST of ATP-dependent DNA helicase vs. Ensembl Sea Lamprey
BLAST of ATP-dependent DNA helicase vs. Ensembl Yeast
BLAST of ATP-dependent DNA helicase vs. Ensembl Nematostella
BLAST of ATP-dependent DNA helicase vs. Ensembl Medaka
BLAST of ATP-dependent DNA helicase vs. Planmine SMEST

BLAST of ATP-dependent DNA helicase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
RECQL	4.787e-133	40.39	RecQ like helicase [Source:HGNC Symbol;Acc:HGNC:99...	[more]
RECQL	4.787e-133	40.39	RecQ like helicase [Source:HGNC Symbol;Acc:HGNC:99...	[more]
BLM	1.366e-82	37.19	BLM RecQ like helicase [Source:HGNC Symbol;Acc:HGN...	[more]
BLM	1.733e-82	37.19	BLM RecQ like helicase [Source:HGNC Symbol;Acc:HGN...	[more]
BLM	1.822e-82	37.64	BLM RecQ like helicase [Source:HGNC Symbol;Acc:HGN...	[more]

BLAST of ATP-dependent DNA helicase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
K02F3.12	1.676e-131	37.70	Putative ATP-dependent DNA helicase Q1 [Source:Un...	[more]
K02F3.12	1.676e-131	37.70	Putative ATP-dependent DNA helicase Q1 [Source:Un...	[more]
K02F3.12	4.620e-131	37.70	Putative ATP-dependent DNA helicase Q1 [Source:Un...	[more]
him-6	1.633e-75	33.85	Bloom syndrome protein homolog [Source:UniProtKB/...	[more]
rcq-5	1.673e-58	31.90	ATP-dependent DNA helicase [Source:UniProtKB/TrEM...	[more]

BLAST of ATP-dependent DNA helicase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Blm	4.041e-77	35.23	gene:FBgn0002906 transcript:FBtr0082434	[more]
RecQ5	6.942e-53	28.60	gene:FBgn0027375 transcript:FBtr0100362	[more]
RecQ5	8.011e-53	28.60	gene:FBgn0027375 transcript:FBtr0075714	[more]
RecQ5	3.129e-50	28.76	gene:FBgn0027375 transcript:FBtr0075715	[more]
RecQ4	2.355e-34	30.73	gene:FBgn0040290 transcript:FBtr0076729	[more]

BLAST of ATP-dependent DNA helicase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
recql	3.228e-110	36.20	RecQ helicase-like [Source:ZFIN;Acc:ZDB-GENE-05080...	[more]
recql	3.228e-110	36.20	RecQ helicase-like [Source:ZFIN;Acc:ZDB-GENE-05080...	[more]
recql	1.188e-108	36.02	RecQ helicase-like [Source:ZFIN;Acc:ZDB-GENE-05080...	[more]
recql	7.355e-105	34.71	RecQ helicase-like [Source:ZFIN;Acc:ZDB-GENE-05080...	[more]
blm	4.834e-86	39.04	BLM RecQ like helicase [Source:ZFIN;Acc:ZDB-GENE-0...	[more]

BLAST of ATP-dependent DNA helicase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
recql	5.827e-118	35.93	RecQ like helicase [Source:NCBI gene;Acc:549070]	[more]
recql	3.014e-117	36.85	RecQ like helicase [Source:NCBI gene;Acc:549070]	[more]
recql	2.777e-116	36.59	RecQ like helicase [Source:NCBI gene;Acc:549070]	[more]
recql	2.859e-116	36.99	RecQ like helicase [Source:NCBI gene;Acc:549070]	[more]
blm	3.057e-79	36.38	Bloom syndrome RecQ like helicase [Source:NCBI gen...	[more]

BLAST of ATP-dependent DNA helicase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Recql	1.166e-134	39.37	RecQ protein-like [Source:MGI Symbol;Acc:MGI:10302...	[more]
Recql	1.631e-134	39.37	RecQ protein-like [Source:MGI Symbol;Acc:MGI:10302...	[more]
Recql	1.732e-134	39.37	RecQ protein-like [Source:MGI Symbol;Acc:MGI:10302...	[more]
Blm	7.880e-86	38.08	Bloom syndrome, RecQ like helicase [Source:MGI Sym...	[more]
Blm	8.571e-86	38.08	Bloom syndrome, RecQ like helicase [Source:MGI Sym...	[more]

BLAST of ATP-dependent DNA helicase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q6AYJ1\|RECQ1_RAT	1.706e-134	38.64	ATP-dependent DNA helicase Q1 OS=Rattus norvegicus...	[more]
sp\|Q9Z129\|RECQ1_MOUSE	1.211e-133	39.37	ATP-dependent DNA helicase Q1 OS=Mus musculus OX=1...	[more]
sp\|P46063\|RECQ1_HUMAN	2.299e-132	40.39	ATP-dependent DNA helicase Q1 OS=Homo sapiens OX=9...	[more]
sp\|Q5RF63\|RECQ1_PONAB	1.855e-131	40.47	ATP-dependent DNA helicase Q1 OS=Pongo abelii OX=9...	[more]
sp\|Q9TXJ8\|RECQ1_CAEEL	5.877e-130	37.70	Putative ATP-dependent DNA helicase Q1 OS=Caenorha...	[more]

BLAST of ATP-dependent DNA helicase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
E9G2Y5	9.329e-135	37.91	ATP-dependent DNA helicase OS=Daphnia pulex OX=666...	[more]
J3S495	6.572e-134	39.06	ATP-dependent DNA helicase OS=Crotalus adamanteus ...	[more]
A0A091T4B1	7.639e-134	40.39	ATP-dependent DNA helicase (Fragment) OS=Phaethon ...	[more]
A0A3Q0CWF0	1.111e-133	39.77	ATP-dependent DNA helicase OS=Mesocricetus auratus...	[more]
A0A091RGT0	1.689e-133	40.07	ATP-dependent DNA helicase (Fragment) OS=Mesitorni...	[more]

BLAST of ATP-dependent DNA helicase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
recql	1.487e-117	36.86	RecQ like helicase [Source:NCBI gene;Acc:103027659...	[more]
recql	2.278e-114	37.41	RecQ like helicase [Source:NCBI gene;Acc:103027659...	[more]
recql	2.665e-114	37.41	RecQ like helicase [Source:NCBI gene;Acc:103027659...	[more]
blm	4.526e-86	37.02	BLM RecQ like helicase [Source:NCBI gene;Acc:10304...	[more]
recql5	3.167e-59	32.55	RecQ like helicase 5 [Source:NCBI gene;Acc:1030316...	[more]

BLAST of ATP-dependent DNA helicase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
recql	3.503e-114	34.14	RecQ helicase-like [Source:ZFIN;Acc:ZDB-GENE-05080...	[more]
blm	5.807e-86	35.68	BLM RecQ like helicase [Source:ZFIN;Acc:ZDB-GENE-0...	[more]
recql5	3.240e-64	31.55	RecQ helicase-like 5 [Source:ZFIN;Acc:ZDB-GENE-071...	[more]
ENSPMAT00000005409.1	2.750e-17	30.38	pep scaffold:Pmarinus_7.0:GL485130:385:11513:1 gen...	[more]
DDX41	9.013e-8	27.00	DEAD-box helicase 41 [Source:HGNC Symbol;Acc:HGNC:...	[more]

BLAST of ATP-dependent DNA helicase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5


Match Name	E-value	Identity	Description
SGS1	9.515e-83	33.52	RecQ family nucleolar DNA helicase; role in genome...	[more]
HRQ1	7.433e-16	25.43	3'-5' DNA helicase that has DNA strand annealing a...	[more]
FAL1	1.500e-12	23.70	Nucleolar protein required for maturation of 18S r...	[more]
DBP2	1.976e-8	20.83	ATP-dependent RNA helicase of the DEAD-box protein...	[more]
DBP3	2.932e-8	23.56	RNA-Dependent ATPase, member of DExD/H-box family;...	[more]

BLAST of ATP-dependent DNA helicase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO32632	1.057e-126	36.38	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO34091	4.651e-67	35.38	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO25520	3.985e-44	37.02	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A8...	[more]
EDO32537	1.860e-34	28.03	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO33287	1.872e-31	36.87	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of ATP-dependent DNA helicase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
recql	2.729e-113	35.55	RecQ like helicase [Source:NCBI gene;Acc:101164117...	[more]
recql	2.729e-113	35.55	RecQ like helicase [Source:NCBI gene;Acc:101164117...	[more]
recql	2.729e-113	35.55	RecQ like helicase [Source:NCBI gene;Acc:101164117...	[more]
recql	3.932e-110	34.41	RecQ like helicase [Source:NCBI gene;Acc:101164117...	[more]
blm	1.117e-81	35.06	BLM RecQ like helicase [Source:NCBI gene;Acc:10004...	[more]

BLAST of ATP-dependent DNA helicase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000064966.1	0.000e+0	98.54	SMESG000064966.1	[more]
SMESG000064967.1	1.101e-154	61.18	SMESG000064967.1	[more]
SMESG000060148.1	1.159e-79	31.05	SMESG000060148.1	[more]
SMESG000028029.1	2.669e-57	35.53	SMESG000028029.1	[more]
SMESG000064968.1	5.736e-50	59.46	SMESG000064968.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30018991 ID=SMED30018991|Name=ATP-dependent DNA helicase|organism=Schmidtea mediterranea sexual|type=transcript|length=2149bp
AAATAATTGAATAACTTATTAATTATTTTATAAAATCAGGATCTTAATTT
TTTTGTGAATTAGCTTATTTTATTCCAAAATTTTTAGAACTCAATGAACA
ATTCCTCTGAAATTGATAAAAGAATTGTTGCTATAGATAATGAAATTAAA
ACTCTTACACATGAAAAAGAAGATTTAATTAAAAAAAAGAAACAGTTATC
TATATCCACGAAAGGACACTCGATTACTTCAAATAAAGATTATGGAAAAG
AAAATTTTCCATGGTCATCAAATATTAAGAAGTTGTTGCAAGATAAATTT
AAAATTAAAAACTTTAAATCATTACAATTGAAAACTATTAATGCCACTTT
GGATAAATTAGATTGTATATTTATATCGTCACCCGGCAGTGGAAAGAGCT
TATGTTACCAATTAGCGTCAATGATTTCAGGATTTACGCTGGTTATTGCT
CCACTGGGTTCATTGATACAGGATCAAATGATTGTATCAGAAAAGTTTGG
TATATCATGTATTTCTCTTGATTCTAACAGTTCTGTAAAAATACAGAATG
AAATATTTAAAGCCATGGAAACTGATCCGGTAGATAATGTAACATATAAA
TTGATTTACACAACTCCGGATAAGATTTCAAACAGTAAAAAACTGACGAA
AGCCATTGAAAAAGCTTATGGTGATAAACGTTTAGTAAGACTGGTTATAG
ACGAAATACATTGCTGCAGTGAATTAAGTCATGATTTTCGTCAAGATTAT
AAAAACCTTCATGGATTGAAATCTCTTTATCCAAATCTGCCAGTTCTTGG
TTTGACAGCAACTGCCAATAATTCTGTAATCAATGATATAAAAACGACTT
TAAATTTGAATTCTGACTGCTTAGTTCATAAAGACAATTATAATCGATCA
AATATCTTCTATGAAGTAAAGTTTTTATCAAATGAAAAAAAAGAAGGTGA
AGAAATTTGTAAATTGATAAAAAGTCGATTTGATGGCCAATCAGGAATTG
TGTTTTGCTTTAATCAAAAAGACTGTGAAAATCTCACTAATGAGCTTGTA
AATAATGGGATTTTAGCATCTTCATATTATGGAACATTGGGATATGATAT
TAAAAAGGATATTCATAATAAATGGCTTAATGAAAATTGCAAGGTAATTG
TGGCCACAAATGCATTCGGAATGGGCATCGATAAACCAAACGTGAGGTTT
GTCATCCATATGTCTATGAGTAAAAGCTTAGAGAATTACTATCAAGAATC
TGGTAGAGCAGGCCGTGACGGTAAAAGATCCGATTGTATTTTGTTCTGGA
AATTAGCAGAATACTTCAAAATTGGTTCAAATATATTTACTGAAAAATCT
GGAATCCCAAATCTTAATATTATGAATCGATATATTTTGGATGATTGCAC
CTGCAAACGGGTATCTCTGTCTTCGATCTTAGATGAAAAATTTACAGTAA
ATGATTGCAAAAATATGTGTTCAGTTTGTGCAGATACTGAATCTGAAATG
TCATCAATCGATATTGCTGATGTTTACAAATCCGCATTGACAATTATTAA
GAACATAGAAAAAACCAAAAATCCAAAAATTACTGGCAAGAAAATAATAT
CAGAACTGGCCAATCAAATGAGTTTATATTTCGCTGATTTGGCTAATCGA
TTTCCTGGAATCGATTATAAATTGTTTCTTGACAAAGCATTTTGTCATTT
GGTTCTTGTTGGCTATCTGAAACTGGATTATAGTTTTGGTTCTTTCAGTA
ATTTCACTTATGTAATTGCCGGAAGTAAAACTCTGAAATCAAACGAAAAA
ATCGATATTCCAATCCGAATCGCTAAATCGGATAAAATGAGAAATCTCGT
TCAAAATGTCAAACAAAATGAATCATCGAATGTCAAGAAAAGTTATTTGA
AACGGCTTTTCAAAGGTTCGAATGATGATATTGTCGAAACGAAAATTCTA
AAACGTTAAGGAAACTGAAATTTTGTTTGTAATTGTGCAATTATTTATTT
TCTATGTCTAATCACGGTTGCCATGAATTTGGGGTAGCGGTTATTTTTAT
GTATTTCTGATAGTGTAATTTTGTACGAATATTATACGAATATCACAATT
TATGTAACTTTTCTCTTTGTAATAAAATTTATTTTCGTCTTTAATCAAA

protein sequence of SMED30018991-orf-1

>SMED30018991-orf-1 ID=SMED30018991-orf-1|Name=SMED30018991-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=622bp
MNNSSEIDKRIVAIDNEIKTLTHEKEDLIKKKKQLSISTKGHSITSNKDY
GKENFPWSSNIKKLLQDKFKIKNFKSLQLKTINATLDKLDCIFISSPGSG
KSLCYQLASMISGFTLVIAPLGSLIQDQMIVSEKFGISCISLDSNSSVKI
QNEIFKAMETDPVDNVTYKLIYTTPDKISNSKKLTKAIEKAYGDKRLVRL
VIDEIHCCSELSHDFRQDYKNLHGLKSLYPNLPVLGLTATANNSVINDIK
TTLNLNSDCLVHKDNYNRSNIFYEVKFLSNEKKEGEEICKLIKSRFDGQS
GIVFCFNQKDCENLTNELVNNGILASSYYGTLGYDIKKDIHNKWLNENCK
VIVATNAFGMGIDKPNVRFVIHMSMSKSLENYYQESGRAGRDGKRSDCIL
FWKLAEYFKIGSNIFTEKSGIPNLNIMNRYILDDCTCKRVSLSSILDEKF
TVNDCKNMCSVCADTESEMSSIDIADVYKSALTIIKNIEKTKNPKITGKK
IISELANQMSLYFADLANRFPGIDYKLFLDKAFCHLVLVGYLKLDYSFGS
FSNFTYVIAGSKTLKSNEKIDIPIRIAKSDKMRNLVQNVKQNESSNVKKS
YLKRLFKGSNDDIVETKILKR*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000028	Category 2 cell
PLANA:0000099	neuron
PLANA:0003117	parapharyngeal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR036388	WH-like_DNA-bd_sf
IPR001650	Helicase_C
IPR014001	Helicase_ATP-bd
IPR011545	DEAD/DEAH_box_helicase_dom
IPR011991	WHTH_DNA-bd_dom
IPR027417	P-loop_NTPase

Vocabulary: **molecular function**
Term	Definition
GO:0003676	nucleic acid binding
GO:0005524	ATP binding
GO:0000166	nucleotide binding
GO:0003677	DNA binding
GO:0003678	DNA helicase activity
GO:0004003	ATP-dependent DNA helicase activity
GO:0004386	helicase activity
GO:0005515	protein binding
GO:0008026	ATP-dependent helicase activity
GO:0009378	four-way junction helicase activity
GO:0016787	hydrolase activity
GO:0036310	annealing helicase activity
GO:0043140	ATP-dependent 3'-5' DNA helicase activity

Vocabulary: **biological process**
Term	Definition
GO:0000724	double-strand break repair via homologous recombination
GO:0000733	DNA strand renaturation
GO:0006281	DNA repair
GO:0006310	DNA recombination
GO:0032508	DNA duplex unwinding

Vocabulary: **cellular component**
Term	Definition
GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0005694	chromosome
GO:0005737	cytoplasm
GO:0016020	membrane

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 254..262
None	No IPR available	GENE3D	G3DSA:3.40.50.300		coord: 1..106 e-value: 1.3E-28 score: 101.9
None	No IPR available	PANTHER	PTHR13710	DNA HELICASE RECQ FAMILY MEMBER	coord: 1..209
None	No IPR available	CDD	cd18794	SF2_C_RecQ	coord: 1..43 e-value: 1.51139E-26 score: 98.4348
IPR001650	Helicase, C-terminal	PFAM	PF00271	Helicase_C	coord: 2..33 e-value: 6.6E-6 score: 26.4
IPR001650	Helicase, C-terminal	PROSITE	PS51194	HELICASE_CTER	coord: 1..73 score: 10.22
IPR036388	Winged helix-like DNA-binding domain superfamily	GENE3D	G3DSA:1.10.10.10		coord: 109..219 e-value: 8.7E-8 score: 34.0
IPR027417	P-loop containing nucleoside triphosphate hydrolase	SUPERFAMILY	SSF52540	P-loop containing nucleoside triphosphate hydrolases	coord: 1..119