Innexin

Overview
NameInnexin
Smed IDSMED30018935
Length (bp)1001
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Innexin (SMED30018935) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Innexin (SMED30018935) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30018935

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 5

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
nervous systemSMED30018935h1SMcG0005853 dd_Smed_v4_16507_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30018935h1SMcG0005853 dd_Smed_v4_16507_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymaSMED30018935h1SMcG0005853 dd_Smed_v4_16507_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30018935h1SMcG0005853 dd_Smed_v4_16507_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
dorsal ventral margin of the whole animalSMED30018935h1SMcG0005853 dd_Smed_v4_16507_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Innexin vs. Ensembl Celegans
Match: inx-5 (Innexin-5 [Source:UniProtKB/Swiss-Prot;Acc:Q23027])

HSP 1 Score: 63.929 bits (154), Expect = 5.628e-21
Identity = 45/158 (28.48%), Postives = 80/158 (50.63%), Query Frame = 2 
Query:  539 K*NLFKSQIISREDSRANFVKSNKRN--------------GRFLPHIVFYIVLKLFYIGLAIGEIFLIQIFLGMKNIYFPIQMFLNSSRNIEWSTTGNFPIVTWCRILIKDNRDNYARNIQCTLPWNTVHDKLFIIIWMSLV-VGIVLMCFNISYWII 967
            K N+   Q+ + +  R  F K N RN              G+FLP +  Y+++K+ Y+   + + +++  FL  K+  +  Q F +     EW TTG FP VT C   I D    +  +IQC +  N + +K+++  W  L+ VG++ +C +++YW +
Sbjct:  153 KSNMSDDQVKATKFGRYFFKKLNFRNESPVFKETGSVVASGKFLPAL--YLLVKILYLANIVLQFWILTYFLETKSWMWGWQTFQDLMAGREWETTGIFPRVTMCDFSIMDLTSVHDHSIQCVIVINMLAEKVYVFFWFWLLFVGLLTVC-SLAYWAV 307

HSP 2 Score: 55.8398 bits (133), Expect = 5.628e-21
Identity = 29/123 (23.58%), Postives = 59/123 (47.97%), Query Frame = 3 
Query:   93 EKFHRNNFPNDLIDEYFAKILPIMFLLFAIILTTKDYIFQNLVCVIPKLWIRAHEEYSKAMCWADSTYFM--------NINNKSPANNQELDKLKIKYYQYVPLFIVCLAVGLIIPRNVWKLF 437
             KF R+   ND+ D +  +    +    AI++    Y+ + + C +P  + R  E+Y++  C+   TYF+         ++  SP ++      ++ YYQ++P+ +V  A    +P  +W+ F
Sbjct:   10 RKFQRSAESNDIADRFSYQYTSTLLGFSAIMMAASQYVGRPIQCWVPAQFTRTWEKYAETYCFIKGTYFLPGAFASEGEMSVTSP-DDAVTATPQVGYYQWIPIVLVLQAFLFYLPSIIWRTF 131
[Close]
BLAST of Innexin vs. Ensembl Celegans
Match: eat-5 (Innexin eat-5 [Source:UniProtKB/Swiss-Prot;Acc:Q27295])

HSP 1 Score: 63.5438 bits (153), Expect = 3.440e-19
Identity = 35/152 (23.03%), Postives = 75/152 (49.34%), Query Frame = 3 
Query:  108 NNFPNDLIDEYFAKILPIMFLLFAIILTTKDYIFQNLVCVIPKLWIRAHEEYSKAMCWADSTYFMNINNKSPANNQELDKLKIKYYQYVPLFIVCLAVGLIIPRNVWKLFCGPLGIDIIHTIEIFSTLSQYGTKNQRKIIIYIENKICSNLK 563
            ++   D ++ Y++ ++    +  ++ +T + Y+   L C +P  + +A E+Y++  C+  +TY++  N+K P   +E    ++ YYQ+ P  +   A    +P   W +     GI+II  +E         ++ ++K I  I   I +NL+
Sbjct:   16 DDLGTDRLNYYYSTLI---IMGMSLTITARQYVGSPLQCWVPAQFTKAWEQYAEDYCFVYNTYWVKPNDKVPLTVEERVSQQLIYYQWAPFIMAIEAAFFYLPVIFWSMLSTKSGINIIKLVETAQKAEGAESEERKKQIDIICRHISNNLR 164

HSP 2 Score: 50.0618 bits (118), Expect = 3.440e-19
Identity = 35/131 (26.72%), Postives = 70/131 (53.44%), Query Frame = 2 
Query:  611 RNGRFLPHIVFYIVLKLFYIGLAIGEIFLIQIFLGMKNIYFPIQMFLNSSRNIEWSTTGNFPIVTWCRILIK--DNRDNYARNIQCTLPWNTVHDK--LFIIIWMSLVVGIVL-----MCFNI--SYWIIE 970
            ++G+++ ++  Y+V KL Y+  +  + +    FLG  + Y+ +++  +  +  +W  +GNFP +  C   ++   N   Y+  IQC L  N  ++K  LF+ IW  LV  + L     +C+N+  S+ ++E
Sbjct:  185 QHGKYITNV--YLVTKLIYMTNSFLQFYSTNKFLGQNDPYWGMRILDDILKGTDWEHSGNFPRIAMCDFQVRVLGNLQRYS--IQCVLTLNMFNEKIFLFLYIWFLLVFFVTLFDSIFLCYNMFSSHKLVE 311
[Close]
BLAST of Innexin vs. Ensembl Celegans
Match: eat-5 (Innexin eat-5 [Source:UniProtKB/Swiss-Prot;Acc:Q27295])

HSP 1 Score: 63.5438 bits (153), Expect = 3.440e-19
Identity = 35/152 (23.03%), Postives = 75/152 (49.34%), Query Frame = 3 
Query:  108 NNFPNDLIDEYFAKILPIMFLLFAIILTTKDYIFQNLVCVIPKLWIRAHEEYSKAMCWADSTYFMNINNKSPANNQELDKLKIKYYQYVPLFIVCLAVGLIIPRNVWKLFCGPLGIDIIHTIEIFSTLSQYGTKNQRKIIIYIENKICSNLK 563
            ++   D ++ Y++ ++    +  ++ +T + Y+   L C +P  + +A E+Y++  C+  +TY++  N+K P   +E    ++ YYQ+ P  +   A    +P   W +     GI+II  +E         ++ ++K I  I   I +NL+
Sbjct:   16 DDLGTDRLNYYYSTLI---IMGMSLTITARQYVGSPLQCWVPAQFTKAWEQYAEDYCFVYNTYWVKPNDKVPLTVEERVSQQLIYYQWAPFIMAIEAAFFYLPVIFWSMLSTKSGINIIKLVETAQKAEGAESEERKKQIDIICRHISNNLR 164

HSP 2 Score: 50.0618 bits (118), Expect = 3.440e-19
Identity = 35/131 (26.72%), Postives = 70/131 (53.44%), Query Frame = 2 
Query:  611 RNGRFLPHIVFYIVLKLFYIGLAIGEIFLIQIFLGMKNIYFPIQMFLNSSRNIEWSTTGNFPIVTWCRILIK--DNRDNYARNIQCTLPWNTVHDK--LFIIIWMSLVVGIVL-----MCFNI--SYWIIE 970
            ++G+++ ++  Y+V KL Y+  +  + +    FLG  + Y+ +++  +  +  +W  +GNFP +  C   ++   N   Y+  IQC L  N  ++K  LF+ IW  LV  + L     +C+N+  S+ ++E
Sbjct:  185 QHGKYITNV--YLVTKLIYMTNSFLQFYSTNKFLGQNDPYWGMRILDDILKGTDWEHSGNFPRIAMCDFQVRVLGNLQRYS--IQCVLTLNMFNEKIFLFLYIWFLLVFFVTLFDSIFLCYNMFSSHKLVE 311
[Close]
BLAST of Innexin vs. Ensembl Celegans
Match: inx-3 (Innexin-3 [Source:UniProtKB/Swiss-Prot;Acc:Q19746])

HSP 1 Score: 61.6178 bits (148), Expect = 1.531e-17
Identity = 37/158 (23.42%), Postives = 73/158 (46.20%), Query Frame = 3 
Query:   81 RFFKEKFHRNNFPNDLIDEYFAKILPIMFLLFAIILTTKDYIFQNLVCVIPKLWIRAHEEYSKAMCWADSTYFMNINNKSPANNQELDKLKIKYYQYVPLFIVCLAVGLIIPRNVWKLFCGPLGIDIIHTIEIFSTL----SQYGTKNQRKIIIYIEN 542
            R+  E F    F +D +D         +   F+I+++ K Y+   + C +P  +    E+Y++  C+  +T+F+   ++ P + ++  K +I YYQ+VP+ +   A    +P  +W       G+D    I     L    S+  TK   K++ +I +
Sbjct:    9 RWLSETFKPKTF-DDAVDRLSYVTTATLLAFFSIMVSCKQYVGSAIQCWMPMEFKGGWEQYAEDYCFIQNTFFIPERSEIPGDVEDRQKAEIGYYQWVPIVLAIQAFMFYLPSWIWSSLYKQCGLDFPSVISEAEALRSQDSETRTKGVNKLVDFIGD 165

HSP 2 Score: 46.2098 bits (108), Expect = 1.531e-17
Identity = 24/91 (26.37%), Postives = 44/91 (48.35%), Query Frame = 2 
Query:  638 VFYIVLKLFYIGLAIGEIFLIQIFLGMKNIYFPIQMFLNSSRNIEWSTTGNFPIVTWCRILIKDNRDNYARNIQCTLPWNTVHDKLFIIIW 910
            + YI +KL Y+     +  ++  FLG +   +    F +     EW  +G FP VT C   ++   + +   +QC L  N  ++K+++ IW
Sbjct:  193 MLYICIKLMYLANVFVQFIILNKFLGNETFLWGFHTFADLYAGREWQDSGVFPRVTLCDFSVRKLANVHRYTVQCVLMINMFNEKIYLFIW 283
[Close]
BLAST of Innexin vs. Ensembl Celegans
Match: inx-18 (Innexin [Source:UniProtKB/TrEMBL;Acc:Q8MXG8])

HSP 1 Score: 78.5666 bits (192), Expect = 5.000e-16
Identity = 36/137 (26.28%), Postives = 68/137 (49.64%), Query Frame = 3 
Query:   54 MLSIIHFGFRFFKE--KFHRNNFPNDLIDEYFAKILPIMFLLFAIILTTKDYIFQNLVCVIPKLWIRAHEEYSKAMCWADSTYFMNINNKSPANNQELDKLKIKYYQYVPLFIVCLAVGLIIPRNVWKLFCGPLGID 458
            M+     G  F     +F      +D +D         M L+FA++++ K Y+   + C +P  + RA E+Y++  CW  +TY++   +  P    + ++ +I YYQ+VP  +   A+   IP +VW++  G  G++
Sbjct:    1 MVGGFRIGMHFLASALRFLEPRVDDDFVDRLHYLYTSTMVLMFAVLVSAKQYVGHPIECFVPAQFTRAMEQYTENYCWVQNTYWVPFQDLIPHRLDDRERRQIGYYQWVPFVLAVAALTFHIPSSVWRMLAGQSGLN 137

HSP 2 Score: 50.447 bits (119), Expect = 1.008e-6
Identity = 32/120 (26.67%), Postives = 57/120 (47.50%), Query Frame = 2 
Query:  644 YIVLKLFYIGLAIGEIFLIQIFLGMKNI-YFPIQMFLNSSRNIEWSTTGNFPIVTWCRILIKDNRDNYARNIQCTLPWNTVHDKLFIIIWMSLVVGIVLMCFNISYWIIEIFCPSQQKLF 1000
            YI +K  ++   I +  L+  FL   +   F   +  +     EW  +G FP VT C   I+   + +   +QC L  N + +K+FI +W+ L V  ++   N+ +W I +   S ++ F
Sbjct:  204 YIFIKALHLANVILQFMLLNSFLQTSDYPMFGAHVLYDLFMGREWRDSGKFPRVTLCDFEIRVLGNVHRHTVQCVLVINMLTEKIFIFLWLWLTVLAIVTALNLIFWFIALVSNSCREHF 323
[Close]
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|Q23027|INX5_CAEEL (Innexin-5 OS=Caenorhabditis elegans OX=6239 GN=inx-5 PE=3 SV=2)

HSP 1 Score: 63.929 bits (154), Expect = 5.717e-20
Identity = 45/158 (28.48%), Postives = 80/158 (50.63%), Query Frame = 2 
Query:  539 K*NLFKSQIISREDSRANFVKSNKRN--------------GRFLPHIVFYIVLKLFYIGLAIGEIFLIQIFLGMKNIYFPIQMFLNSSRNIEWSTTGNFPIVTWCRILIKDNRDNYARNIQCTLPWNTVHDKLFIIIWMSLV-VGIVLMCFNISYWII 967
            K N+   Q+ + +  R  F K N RN              G+FLP +  Y+++K+ Y+   + + +++  FL  K+  +  Q F +     EW TTG FP VT C   I D    +  +IQC +  N + +K+++  W  L+ VG++ +C +++YW +
Sbjct:  153 KSNMSDDQVKATKFGRYFFKKLNFRNESPVFKETGSVVASGKFLPAL--YLLVKILYLANIVLQFWILTYFLETKSWMWGWQTFQDLMAGREWETTGIFPRVTMCDFSIMDLTSVHDHSIQCVIVINMLAEKVYVFFWFWLLFVGLLTVC-SLAYWAV 307

HSP 2 Score: 55.8398 bits (133), Expect = 5.717e-20
Identity = 29/123 (23.58%), Postives = 59/123 (47.97%), Query Frame = 3 
Query:   93 EKFHRNNFPNDLIDEYFAKILPIMFLLFAIILTTKDYIFQNLVCVIPKLWIRAHEEYSKAMCWADSTYFM--------NINNKSPANNQELDKLKIKYYQYVPLFIVCLAVGLIIPRNVWKLF 437
             KF R+   ND+ D +  +    +    AI++    Y+ + + C +P  + R  E+Y++  C+   TYF+         ++  SP ++      ++ YYQ++P+ +V  A    +P  +W+ F
Sbjct:   10 RKFQRSAESNDIADRFSYQYTSTLLGFSAIMMAASQYVGRPIQCWVPAQFTRTWEKYAETYCFIKGTYFLPGAFASEGEMSVTSP-DDAVTATPQVGYYQWIPIVLVLQAFLFYLPSIIWRTF 131
[Close]
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|Q27295|EAT5_CAEEL (Innexin eat-5 OS=Caenorhabditis elegans OX=6239 GN=eat-5 PE=2 SV=1)

HSP 1 Score: 63.5438 bits (153), Expect = 3.495e-18
Identity = 35/152 (23.03%), Postives = 75/152 (49.34%), Query Frame = 3 
Query:  108 NNFPNDLIDEYFAKILPIMFLLFAIILTTKDYIFQNLVCVIPKLWIRAHEEYSKAMCWADSTYFMNINNKSPANNQELDKLKIKYYQYVPLFIVCLAVGLIIPRNVWKLFCGPLGIDIIHTIEIFSTLSQYGTKNQRKIIIYIENKICSNLK 563
            ++   D ++ Y++ ++    +  ++ +T + Y+   L C +P  + +A E+Y++  C+  +TY++  N+K P   +E    ++ YYQ+ P  +   A    +P   W +     GI+II  +E         ++ ++K I  I   I +NL+
Sbjct:   16 DDLGTDRLNYYYSTLI---IMGMSLTITARQYVGSPLQCWVPAQFTKAWEQYAEDYCFVYNTYWVKPNDKVPLTVEERVSQQLIYYQWAPFIMAIEAAFFYLPVIFWSMLSTKSGINIIKLVETAQKAEGAESEERKKQIDIICRHISNNLR 164

HSP 2 Score: 50.0618 bits (118), Expect = 3.495e-18
Identity = 35/131 (26.72%), Postives = 70/131 (53.44%), Query Frame = 2 
Query:  611 RNGRFLPHIVFYIVLKLFYIGLAIGEIFLIQIFLGMKNIYFPIQMFLNSSRNIEWSTTGNFPIVTWCRILIK--DNRDNYARNIQCTLPWNTVHDK--LFIIIWMSLVVGIVL-----MCFNI--SYWIIE 970
            ++G+++ ++  Y+V KL Y+  +  + +    FLG  + Y+ +++  +  +  +W  +GNFP +  C   ++   N   Y+  IQC L  N  ++K  LF+ IW  LV  + L     +C+N+  S+ ++E
Sbjct:  185 QHGKYITNV--YLVTKLIYMTNSFLQFYSTNKFLGQNDPYWGMRILDDILKGTDWEHSGNFPRIAMCDFQVRVLGNLQRYS--IQCVLTLNMFNEKIFLFLYIWFLLVFFVTLFDSIFLCYNMFSSHKLVE 311
[Close]
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|Q19746|INX3_CAEEL (Innexin-3 OS=Caenorhabditis elegans OX=6239 GN=inx-3 PE=1 SV=2)

HSP 1 Score: 61.6178 bits (148), Expect = 1.555e-16
Identity = 37/158 (23.42%), Postives = 73/158 (46.20%), Query Frame = 3 
Query:   81 RFFKEKFHRNNFPNDLIDEYFAKILPIMFLLFAIILTTKDYIFQNLVCVIPKLWIRAHEEYSKAMCWADSTYFMNINNKSPANNQELDKLKIKYYQYVPLFIVCLAVGLIIPRNVWKLFCGPLGIDIIHTIEIFSTL----SQYGTKNQRKIIIYIEN 542
            R+  E F    F +D +D         +   F+I+++ K Y+   + C +P  +    E+Y++  C+  +T+F+   ++ P + ++  K +I YYQ+VP+ +   A    +P  +W       G+D    I     L    S+  TK   K++ +I +
Sbjct:    9 RWLSETFKPKTF-DDAVDRLSYVTTATLLAFFSIMVSCKQYVGSAIQCWMPMEFKGGWEQYAEDYCFIQNTFFIPERSEIPGDVEDRQKAEIGYYQWVPIVLAIQAFMFYLPSWIWSSLYKQCGLDFPSVISEAEALRSQDSETRTKGVNKLVDFIGD 165

HSP 2 Score: 46.2098 bits (108), Expect = 1.555e-16
Identity = 24/91 (26.37%), Postives = 44/91 (48.35%), Query Frame = 2 
Query:  638 VFYIVLKLFYIGLAIGEIFLIQIFLGMKNIYFPIQMFLNSSRNIEWSTTGNFPIVTWCRILIKDNRDNYARNIQCTLPWNTVHDKLFIIIW 910
            + YI +KL Y+     +  ++  FLG +   +    F +     EW  +G FP VT C   ++   + +   +QC L  N  ++K+++ IW
Sbjct:  193 MLYICIKLMYLANVFVQFIILNKFLGNETFLWGFHTFADLYAGREWQDSGVFPRVTLCDFSVRKLANVHRYTVQCVLMINMFNEKIYLFIW 283
[Close]
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|O61787|INX16_CAEEL (Innexin-16 OS=Caenorhabditis elegans OX=6239 GN=inx-16 PE=3 SV=2)

HSP 1 Score: 53.9138 bits (128), Expect = 1.280e-13
Identity = 34/158 (21.52%), Postives = 73/158 (46.20%), Query Frame = 3 
Query:  129 IDEYFAKILPIMFLLFAIILTTKDYIFQNLVCVIPKLWIRAHEEYSKAMCWADSTYFMNINNKSPANNQELDKLKIKYYQYVPLFIVCLAVGLIIPRNVWKLFCGPLGIDIIHTIEIFSTLSQYGTKNQRKIIIYIENKICSNLK*YQEKTRGLILLN 602
            ID     +   + + F+++L  K+Y+ + + C  P  +    E ++++ C+ ++TYF+ + + +    +  +  ++ YYQ+VP  +V  A+   +PR  W ++    G+ I   I    T ++   K        +E     N +  Q+K  G  + N
Sbjct:   25 IDRLNYVVTTSILIAFSLLLFAKNYVGEPMQCWTPNQFAGGWESFAESYCFIENTYFVPMQDSNLPAAETREGREMIYYQWVPFLLVIQALFFCVPRAFWIIYPSYSGLTIADMI----TAARQNGKQLEGADEALEQVAMINWRTEQQKGHGSRIFN 178

HSP 2 Score: 43.8986 bits (102), Expect = 1.280e-13
Identity = 30/118 (25.42%), Postives = 58/118 (49.15%), Query Frame = 2 
Query:  644 YIVLKLFYIGLAIGEIFLIQIFLGMKNIYFPIQMFLNSSRNIEWSTTGNFPIVTWCRILIKDNRDNYARNIQCTLPWNTVHDKLFIIIWMSLVVGIVLMCFNISYWIIEIFCPSQQKL 997
            Y+V+KL  +   + + FL+  FL     ++   +F +      W  +G+FP V++C I +++  + +  ++QC L  N  ++K+FI +W      +V    +   W+   F  S  KL
Sbjct:  180 YLVMKLLILLNIVLQFFLLNSFLNTAYTFWGWGIFWDMVNGRHWQESGHFPRVSFCDINVRELGNIHHWSLQCVLMVNMFNEKIFIFLWFWFAFLLVATAGDFVIWVWRRF-DSNSKL 296
[Close]
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|Q23157|INX11_CAEEL (Innexin-11 OS=Caenorhabditis elegans OX=6239 GN=inx-11 PE=3 SV=1)

HSP 1 Score: 58.5362 bits (140), Expect = 2.999e-13
Identity = 35/151 (23.18%), Postives = 70/151 (46.36%), Query Frame = 3 
Query:  120 NDLIDEYFAKILPIMFLLFAIILTTKDYIFQNLVCVIPKLWIRAHEEYSKAMCWADSTYFMNINNKSPANNQE---LDKLKIKYYQYVPLFIVCLAVGLIIPRNVWKLFCGPLGIDIIHTIEIFSTLSQYGTKNQRKIIIYIENKICSNLK 563
            +D  D     + P + L F+++++ K +  + + C+ P  +  + E+Y++  CW+  TYF+          +E       ++ YYQ+VP F++  A     P  +WK F    GI I   +E     +    + + K I+ ++  + S L+
Sbjct:   20 DDWSDRLNYLMTPNILLAFSVLISFKQFGGRPIECMFPNKFPGSWEQYAENYCWSQDTYFVEPTQDVSLLKKEERYTPDRQLSYYQWVPFFLLLQAAFFRAPSYLWKYFSNHSGIRIHEVVEKAKDSANVEEEVREKNILILKRHLSSALR 170

HSP 2 Score: 38.1206 bits (87), Expect = 2.999e-13
Identity = 25/120 (20.83%), Postives = 56/120 (46.67%), Query Frame = 2 
Query:  644 YIVLKLFYIGLAIGEIFLIQIFLGM-KNIYFPIQMFLNSSRNIEWSTTGNFPIVTWCRILIKDNRDNYARNIQCTLPWNTVHDKLFIIIWMSLVVGIVLMCFNISYWIIEIFCPSQQKLF 1000
            Y+  K+ Y      +++L+  FLG  ++ ++   +  +  +   W  +G FP    C   ++   +    ++QC L  N  ++K+F+++W   V+ ++    ++  W I +  P   K F
Sbjct:  202 YLFTKVLYFLNVFAQLYLMNYFLGTNRHHWYGFGVVQDIVQGEPWERSGYFPRAAVCDFEVRQVANIQRYSVQCVLVINIFNEKIFVLLWFWYVILLLSSTVSLVQWFIVLVFPCFSKWF 321
[Close]
BLAST of Innexin vs. TrEMBL
Match: A0A1I8IJF7 (Innexin OS=Macrostomum lignano OX=282301 GN=inx PE=3 SV=1)

HSP 1 Score: 79.337 bits (194), Expect = 2.647e-27
Identity = 46/174 (26.44%), Postives = 90/174 (51.72%), Query Frame = 3 
Query:   78 FRFFKEKFHRNNFPNDLIDEYFAKILPIMFLLFAIILTTKDYIFQNLVCVIPKLWIRAHEEYSKAMCWADSTYFMNINNKS-PANNQELDKLKIKYYQYVPLFIVCLAVGLIIPRNVWKLFCGPLGIDIIHTIEIFSTLSQYGTKNQRKIII-YIENKICSNLK*YQEKTRGLI 593
            FR    K  R++   D +   F+  +    ++F+++++ + YI + + C +P  + RA EEY++ +CW  STY+++ +  + P +N +  +  I YYQ+VPL ++  A    +PR VW+LF    GI + + +E+   +        R+  + Y+   I  +L   +E   G +
Sbjct:   12 FRLDPAKHRRDDDFADRMSHMFSTAI---IVVFSLVISCRQYIGKPIACWVPTEFTRAQEEYTENVCWVTSTYYLDTSGVNFPVSNADRYRQSIGYYQWVPLVLLIQAFLFNLPRLVWRLFNWQSGIQLSNIMEVAGDVEMIKDPLSRQTSVRYVAKHIEDSLGAQREYRAGCL 182

HSP 2 Score: 72.4034 bits (176), Expect = 2.647e-27
Identity = 39/121 (32.23%), Postives = 67/121 (55.37%), Query Frame = 2 
Query:  605 NKRNGRFLPHIVFYIVLKLFYIGLAIGEIFLIQIFLGMKNIYFPIQMFLNSSRNIEWSTTGNFPIVTWCRILIKDNRDNYARN-IQCTLPWNTVHDKLFIIIWMSLVVGIVLMCFNISYWI 964
             KR G FL  +  Y++ K+ YI   IG+ FL+  +LG    ++ +++  + +   EW  +GNFP +T C   I+    N  R+ +QC LP N  ++K++I +W  +V+  VL   +  +WI
Sbjct:  199 GKRYGNFL--VCLYLICKVLYITNVIGQFFLMNKYLGTNYTFYGLELLRDLAEGREWEESGNFPRITMCDFHIRKMGANMHRHTVQCVLPINMFNEKIYIFLWFWMVLVSVLSISSFIFWI 317
[Close]
BLAST of Innexin vs. TrEMBL
Match: A0A1I8HVQ8 (Innexin OS=Macrostomum lignano OX=282301 GN=inx PE=3 SV=1)

HSP 1 Score: 79.337 bits (194), Expect = 3.201e-27
Identity = 46/174 (26.44%), Postives = 90/174 (51.72%), Query Frame = 3 
Query:   78 FRFFKEKFHRNNFPNDLIDEYFAKILPIMFLLFAIILTTKDYIFQNLVCVIPKLWIRAHEEYSKAMCWADSTYFMNINNKS-PANNQELDKLKIKYYQYVPLFIVCLAVGLIIPRNVWKLFCGPLGIDIIHTIEIFSTLSQYGTKNQRKIII-YIENKICSNLK*YQEKTRGLI 593
            FR    K  R++   D +   F+  +    ++F+++++ + YI + + C +P  + RA EEY++ +CW  STY+++ +  + P +N +  +  I YYQ+VPL ++  A    +PR VW+LF    GI + + +E+   +        R+  + Y+   I  +L   +E   G +
Sbjct:   12 FRLDPAKHRRDDDFADRMSHMFSTAI---IVVFSLVISCRQYIGKPIACWVPTEFTRAQEEYTENVCWVTSTYYLDTSGVNFPVSNADRYRQSIGYYQWVPLVLLIQAFLFNLPRLVWRLFNWQSGIQLSNIMEVAGDVEMIKDPLSRQTSVRYVAKHIEDSLGAQREYRAGCL 182

HSP 2 Score: 72.4034 bits (176), Expect = 3.201e-27
Identity = 39/121 (32.23%), Postives = 67/121 (55.37%), Query Frame = 2 
Query:  605 NKRNGRFLPHIVFYIVLKLFYIGLAIGEIFLIQIFLGMKNIYFPIQMFLNSSRNIEWSTTGNFPIVTWCRILIKDNRDNYARN-IQCTLPWNTVHDKLFIIIWMSLVVGIVLMCFNISYWI 964
             KR G FL  +  Y++ K+ YI   IG+ FL+  +LG    ++ +++  + +   EW  +GNFP +T C   I+    N  R+ +QC LP N  ++K++I +W  +V+  VL   +  +WI
Sbjct:  199 GKRYGNFL--VCLYLICKVLYITNVIGQFFLMNKYLGTNYTFYGLELLRDLAEGREWEESGNFPRITMCDFHIRKMGANMHRHTVQCVLPINMFNEKIYIFLWFWMVLVSVLSISSFIFWI 317
[Close]
BLAST of Innexin vs. TrEMBL
Match: A0A1I8GM50 (Innexin OS=Macrostomum lignano OX=282301 GN=inx PE=3 SV=1)

HSP 1 Score: 78.5666 bits (192), Expect = 5.039e-27
Identity = 46/174 (26.44%), Postives = 89/174 (51.15%), Query Frame = 3 
Query:   78 FRFFKEKFHRNNFPNDLIDEYFAKILPIMFLLFAIILTTKDYIFQNLVCVIPKLWIRAHEEYSKAMCWADSTYFMNINNKS-PANNQELDKLKIKYYQYVPLFIVCLAVGLIIPRNVWKLFCGPLGIDIIHTIEIFSTLSQYGTKNQRKIII-YIENKICSNLK*YQEKTRGLI 593
            FR    K  R++   D +   F+  + + F   +++++ + YI + + C +P  + RA EEY++ +CW  STY+++ +  + P +N +  +  I YYQ+VPL ++  A    +PR VW+LF    GI + + +E+   +        R+  + Y+   I  +L   +E   G +
Sbjct:   12 FRLDPAKHRRDDDFADRMSHMFSTAIIVAF---SLVISCRQYIGKPIACWVPTEFTRAQEEYTENVCWVTSTYYLDTSGVNFPVSNADRYRQSIGYYQWVPLVLLIQAFLFNLPRLVWRLFNWQSGIQLSNIMEVAGDVEMIKDPLSRQTSVRYVAKHIEDSLGAQREYRAGCL 182

HSP 2 Score: 72.4034 bits (176), Expect = 5.039e-27
Identity = 39/121 (32.23%), Postives = 67/121 (55.37%), Query Frame = 2 
Query:  605 NKRNGRFLPHIVFYIVLKLFYIGLAIGEIFLIQIFLGMKNIYFPIQMFLNSSRNIEWSTTGNFPIVTWCRILIKDNRDNYARN-IQCTLPWNTVHDKLFIIIWMSLVVGIVLMCFNISYWI 964
             KR G FL  +  Y++ K+ YI   IG+ FL+  +LG    ++ +++  + +   EW  +GNFP +T C   I+    N  R+ +QC LP N  ++K++I +W  +V+  VL   +  +WI
Sbjct:  199 GKRYGNFL--VCLYLICKVLYITNVIGQFFLMNKYLGTNYTFYGLELLRDLAEGREWEESGNFPRITMCDFHIRKMGANMHRHTVQCVLPINMFNEKIYIFLWFWMVLVSVLSISSFIFWI 317
[Close]
BLAST of Innexin vs. TrEMBL
Match: A0A158R819 (Innexin OS=Taenia asiatica OX=60517 GN=inx PE=3 SV=1)

HSP 1 Score: 86.6557 bits (213), Expect = 2.075e-26
Identity = 50/177 (28.25%), Postives = 89/177 (50.28%), Query Frame = 3 
Query:   69 HF--GFRFFKEKFHRNNFPNDLIDEYFAKILPIMFLLFAIILTTKDYIFQNLVCVIPKLWIRAHEEYSKAMCWADSTYFMNINNKS-PANNQELDKLKIKYYQYVPLFIVCLAVGLIIPRNVWKLFCGPLGIDIIHTIEIFSTLSQYGTKNQRKI-IIYIENKICSNLK*YQEKTRG 587
            HF  G   FK    ++   +D  D +      ++ ++F ++++ + YI + + C +P  + RA EEY++++CW  STYF+    K+ P + QE ++ KI YYQ+VP  ++  A    +P  +W+LF    GI +   +E+   +      + RK  I Y+   I   L   +E   G
Sbjct:    4 HFFAGLTKFKLDAGKHRRDDDFADRFSHNFTTLLLVIFTLVVSARQYIGKPIACWVPTEFTRAQEEYAESVCWVTSTYFLPTKQKTVPESTQEREERKILYYQWVPFVLMIQAFLFNLPCIIWRLFNWQSGIHLSSIMEVSCDIEMIRDPDSRKSNITYVARHIEDALTSQREYRDG 180

HSP 2 Score: 62.003 bits (149), Expect = 2.075e-26
Identity = 33/119 (27.73%), Postives = 60/119 (50.42%), Query Frame = 2 
Query:  605 NKRNGRFLPHIVFYIVLKLFYIGLAIGEIFLIQIFLGMKNIYFPIQMFLNSSRNIEWSTTGNFPIVTWCRILIKDNRDNYARNIQCTLPWNTVHDKLFIIIWMSLVVGIVLMCFNISYW 961
             KR G +L  I  Y++ K  YI   +G+ FL+   LG    ++ + +  + +    W  +GNFP +T C   I+   +++   +QC LP N  ++K+FI +W   ++   +   +  YW
Sbjct:  198 GKRYGNYL--ICLYLITKALYIFNVVGQFFLMNRILGTNYTFYGLDLIRDIAEGYLWEESGNFPRITLCDFEIRKLANSHRYTVQCVLPINMFNEKIFIFLWFWFILVSAVSISSFLYW 314
[Close]
BLAST of Innexin vs. TrEMBL
Match: A0A4S2LLY4 (Innexin OS=Opisthorchis felineus OX=147828 GN=inx PE=3 SV=1)

HSP 1 Score: 84.3445 bits (207), Expect = 8.981e-26
Identity = 48/172 (27.91%), Postives = 85/172 (49.42%), Query Frame = 3 
Query:   78 FRFFKEKFHRNNFPNDLIDEYFAKILPIMFLLFAIILTTKDYIFQNLVCVIPKLWIRAHEEYSKAMCWADSTYFMNINNKS-PANNQELDKLKIKYYQYVPLFIVCLAVGLIIPRNVWKLFCGPLGIDIIHTIEIFSTLSQYGTKNQRKI-IIYIENKICSNLK*YQEKTRG 587
            F+    KF R++   D  D +     P++ ++F ++++ + YI + + C +P  + RA EEY++++CW  STYF+     + P N  + +  KI YYQ+VP  ++  A    +P  VW+LF    GI +   +E+   +        RK  + Y+   I   L   +E   G
Sbjct:   12 FKLDAGKFRRDD---DFSDRFSHTFTPLLLVIFTLVISARQYIGKPIACWVPTEFTRAQEEYAESVCWVTSTYFIPTREVNVPVNLADREDRKIHYYQWVPFILMIQAFLFNLPCIVWRLFNWQSGIHLSSIMEVACEIEMIKDPETRKSNVTYVARHIEDALTTQREYRSG 180

HSP 2 Score: 62.3882 bits (150), Expect = 8.981e-26
Identity = 33/119 (27.73%), Postives = 59/119 (49.58%), Query Frame = 2 
Query:  605 NKRNGRFLPHIVFYIVLKLFYIGLAIGEIFLIQIFLGMKNIYFPIQMFLNSSRNIEWSTTGNFPIVTWCRILIKDNRDNYARNIQCTLPWNTVHDKLFIIIWMSLVVGIVLMCFNISYW 961
             KR G +L  I  Y++ K  YI   +G+ F +   LG    ++ I +  + +  I W  +GNFP +T C   ++   + +   +QC LP N  ++K+FI +W   ++   +   +  YW
Sbjct:  198 GKRYGNYL--ICLYLITKSLYILNVVGQFFFMNRILGTNYTFYGIDLLRDIAEGIVWQESGNFPRITLCDFEVRKLANVHRHTVQCVLPINMFNEKIFIFLWFWFILVAAVNTSSFLYW 314
[Close]
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000000713.1 (SMESG000000713.1)

HSP 1 Score: 305.834 bits (782), Expect = 1.779e-157
Identity = 149/149 (100.00%), Postives = 149/149 (100.00%), Query Frame = 2 
Query:  554 KSQIISREDSRANFVKSNKRNGRFLPHIVFYIVLKLFYIGLAIGEIFLIQIFLGMKNIYFPIQMFLNSSRNIEWSTTGNFPIVTWCRILIKDNRDNYARNIQCTLPWNTVHDKLFIIIWMSLVVGIVLMCFNISYWIIEIFCPSQQKLF 1000
            KSQIISREDSRANFVKSNKRNGRFLPHIVFYIVLKLFYIGLAIGEIFLIQIFLGMKNIYFPIQMFLNSSRNIEWSTTGNFPIVTWCRILIKDNRDNYARNIQCTLPWNTVHDKLFIIIWMSLVVGIVLMCFNISYWIIEIFCPSQQKLF
Sbjct:  132 KSQIISREDSRANFVKSNKRNGRFLPHIVFYIVLKLFYIGLAIGEIFLIQIFLGMKNIYFPIQMFLNSSRNIEWSTTGNFPIVTWCRILIKDNRDNYARNIQCTLPWNTVHDKLFIIIWMSLVVGIVLMCFNISYWIIEIFCPSQQKLF 280

HSP 2 Score: 269.626 bits (688), Expect = 1.779e-157
Identity = 131/131 (100.00%), Postives = 131/131 (100.00%), Query Frame = 3 
Query:  162 MFLLFAIILTTKDYIFQNLVCVIPKLWIRAHEEYSKAMCWADSTYFMNINNKSPANNQELDKLKIKYYQYVPLFIVCLAVGLIIPRNVWKLFCGPLGIDIIHTIEIFSTLSQYGTKNQRKIIIYIENKICS 554
            MFLLFAIILTTKDYIFQNLVCVIPKLWIRAHEEYSKAMCWADSTYFMNINNKSPANNQELDKLKIKYYQYVPLFIVCLAVGLIIPRNVWKLFCGPLGIDIIHTIEIFSTLSQYGTKNQRKIIIYIENKICS
Sbjct:    1 MFLLFAIILTTKDYIFQNLVCVIPKLWIRAHEEYSKAMCWADSTYFMNINNKSPANNQELDKLKIKYYQYVPLFIVCLAVGLIIPRNVWKLFCGPLGIDIIHTIEIFSTLSQYGTKNQRKIIIYIENKICS 131
[Close]
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000035987.1 (SMESG000035987.1)

HSP 1 Score: 86.6557 bits (213), Expect = 5.175e-31
Identity = 50/166 (30.12%), Postives = 88/166 (53.01%), Query Frame = 3 
Query:   96 KFHRNNFPNDLIDEYFAKILPIMFLLFAIILTTKDYIFQNLVCVIPKLWIRAHEEYSKAMCWADSTYFMNINNKS-PANNQELDKLKIKYYQYVPLFIVCLAVGLIIPRNVWKLFCGPLGIDIIHTIEIFSTLSQYGTKNQRKI-IIYIENKICSNLK*YQEKTRG 587
            KF R++  +D  + +F  IL    + F+++++T+ Y+ + + C +P  +  + EEY++++CW  STYF+N    S P N Q+ ++ KI YYQ+VP  ++  A+    P  VW+L     G++I   I+I           QRK  + +I   I   L+  +E   G
Sbjct:   18 KFRRDDDQSDRFNHFFTTIL---LVCFSLVVSTRQYVGKPIACWVPTEFTSSQEEYAESICWVSSTYFINPYQGSIPENTQQREEKKILYYQWVPFILMLQAILFNFPCCVWRLLNWQSGLNISAIIDIAGDTEMIKDYEQRKANLDFITRHIDDTLRIQREYRNG 180

HSP 2 Score: 66.6254 bits (161), Expect = 5.175e-31
Identity = 38/129 (29.46%), Postives = 64/129 (49.61%), Query Frame = 2 
Query:  605 NKRNGRFLPHIVFYIVLKLFYIGLAIGEIFLIQIFLGMKNIYFPIQMFLNSSRNIEWSTTGNFPIVTWCRILIKDNRDNYARNIQCTLPWNTVHDKLFIIIWMSLVVGIVLMCFNISYWIIEIFCPSQQ 991
             +R G +L  +  Y + K  YI   IG+ FL+  FLG    ++ + +    S   EW+ +GNFP VT C   I+   + +   +QC LP N  ++K+FI +W   V   ++   +  +W  +  C  Q+
Sbjct:  198 GRRYGNYL--VCVYTICKSLYILNVIGQFFLMNRFLGTNYTFYGLDLIYQLSIGNEWTESGNFPRVTMCDFNIRKLANQHRYTVQCVLPINLFNEKIFIFLWFWFVFIAIITVHSFIHWTSKSVCRIQR 324
[Close]
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000046667.1 (SMESG000046667.1)

HSP 1 Score: 83.9593 bits (206), Expect = 2.464e-26
Identity = 51/183 (27.87%), Postives = 96/183 (52.46%), Query Frame = 3 
Query:   78 FRFFKEKFHRNNFPNDLIDEYFAKILPIMFLLFAIILTTKDYIFQNLVCVIPKLWIRAHEEYSKAMCWADSTYFMNINNKS-PANNQELDKLKIKYYQYVPLFIVCLAVGLIIPRNVWKLFCGPLGIDIIHTIEIFSTLSQYGTKNQRKI-IIYIENKI--CSNLK*YQEKTRGLILLNQIKE 614
            F+++  +F R++   D ++  F   L    ++F +I++ + YI + + C +P  + RA EEY++++CW  STYF+     S P N  + +  K+ YYQ+VP  ++  A    IP  +W+LF    GI+++  +++   +     +  RK+ + Y+ + I  C N +     T G  + N I E
Sbjct:   12 FKWYAGRFMRDDDFADRLNHTFTSFL---LVIFTLIISARQYIGKPIACWVPTEFSRAQEEYAESVCWVTSTYFVEPGVHSIPQNIDDREDRKLLYYQWVPFILMGQAFLFNIPCIIWRLFNWQSGINLVSVMQVACDVEIIKDRECRKVNVSYVAHHIDQCLNTRHVNRNTVGGRMRNFIAE 191

HSP 2 Score: 53.5286 bits (127), Expect = 2.464e-26
Identity = 29/102 (28.43%), Postives = 51/102 (50.00%), Query Frame = 2 
Query:  605 NKRNGRFLPHIVFYIVLKLFYIGLAIGEIFLIQIFLGMKNIYFPIQMFLNSSRNIEWSTTGNFPIVTWCRILIKDNRDNYARNIQCTLPWNTVHDKLFIIIW 910
            +K  G +L  I  YI+ K+ YI   I + F++   LG    ++   +    +    W  +G+FP +T C   I+   + +   +QC LP N  ++K+FI +W
Sbjct:  198 SKMYGSYL--ICLYIICKMLYILNVISQFFIMNRVLGTNYTFYGFDLVKQLADGRMWHESGHFPRITMCDFEIRKLANKHRYTVQCVLPINMFNEKIFIFLW 297
[Close]
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000046667.1 (SMESG000046667.1)

HSP 1 Score: 83.9593 bits (206), Expect = 2.546e-26
Identity = 51/183 (27.87%), Postives = 96/183 (52.46%), Query Frame = 3 
Query:   78 FRFFKEKFHRNNFPNDLIDEYFAKILPIMFLLFAIILTTKDYIFQNLVCVIPKLWIRAHEEYSKAMCWADSTYFMNINNKS-PANNQELDKLKIKYYQYVPLFIVCLAVGLIIPRNVWKLFCGPLGIDIIHTIEIFSTLSQYGTKNQRKI-IIYIENKI--CSNLK*YQEKTRGLILLNQIKE 614
            F+++  +F R++   D ++  F   L    ++F +I++ + YI + + C +P  + RA EEY++++CW  STYF+     S P N  + +  K+ YYQ+VP  ++  A    IP  +W+LF    GI+++  +++   +     +  RK+ + Y+ + I  C N +     T G  + N I E
Sbjct:   26 FKWYAGRFMRDDDFADRLNHTFTSFL---LVIFTLIISARQYIGKPIACWVPTEFSRAQEEYAESVCWVTSTYFVEPGVHSIPQNIDDREDRKLLYYQWVPFILMGQAFLFNIPCIIWRLFNWQSGINLVSVMQVACDVEIIKDRECRKVNVSYVAHHIDQCLNTRHVNRNTVGGRMRNFIAE 205

HSP 2 Score: 53.5286 bits (127), Expect = 2.546e-26
Identity = 26/92 (28.26%), Postives = 46/92 (50.00%), Query Frame = 2 
Query:  635 IVFYIVLKLFYIGLAIGEIFLIQIFLGMKNIYFPIQMFLNSSRNIEWSTTGNFPIVTWCRILIKDNRDNYARNIQCTLPWNTVHDKLFIIIW 910
            I  YI+ K+ YI   I + F++   LG    ++   +    +    W  +G+FP +T C   I+   + +   +QC LP N  ++K+FI +W
Sbjct:  220 ICLYIICKMLYILNVISQFFIMNRVLGTNYTFYGFDLVKQLADGRMWHESGHFPRITMCDFEIRKLANKHRYTVQCVLPINMFNEKIFIFLW 311
[Close]
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000048374.1 (SMESG000048374.1)

HSP 1 Score: 68.9366 bits (167), Expect = 1.077e-25
Identity = 44/154 (28.57%), Postives = 76/154 (49.35%), Query Frame = 3 
Query:  114 FPNDLIDEYFAKILPIMFLLFAIILTTKDYIFQNLVCVIPKLWIRAHEEYSKAMCWADSTYFMNINNKSPANNQELDKLKIKYYQYVPLFIVCLAVGLIIPRNVWKLFCGPLGIDIIHTIEIF----STLSQYGTKNQRKIIIYIENKICSNLK 563
            F +D +D    +I   +  LF  +L  + YI + + C  P+ + +A E+YS+  CW  +T++  INN  P    +  KL I YYQ+ P+ +   A+   IP  +W+L     G ++   I++     S +    +KN + I  YI+  I  N +
Sbjct:   22 FDDDWVDRLNYQITCFLHFLFIGVLGLRSYIGKPIQCWAPQEFNKAWEDYSENFCWVSNTFYAPINNNLPLRMDKTSKL-IGYYQWTPIVLAVQALMFYIPCLIWRLLMNYSGFNVRRIIQMAGDTNSLVPDINSKNIKFIARYIDTCIDRNYR 174

HSP 2 Score: 66.6254 bits (161), Expect = 1.077e-25
Identity = 34/120 (28.33%), Postives = 69/120 (57.50%), Query Frame = 2 
Query:  614 NGRFLPHIVFYIVLKLFYIGLAIGEIFLIQIFLGMKNIYFPIQMFLNSSRNIEWSTTGNFPIVTWCRILIKDNRDNYARNIQCTLPWNTVHDKLFIIIWMSLVVGIVLMCFNISYWIIEI 973
            +GRFL     Y ++K+ Y+   + +++L++ FLG  + +F +++ ++     EW+ +GNFP VT+C +  K   +N   N+QC LP N   +K++I +W   V+  ++   +   W++ +
Sbjct:  206 HGRFL--FFLYGIVKVLYVINVLLQMYLMKRFLGTDSNFFGVKVLVDLINGFEWNHSGNFPRVTFCEVQTKKLGENNIYNLQCVLPLNMFLEKIYIFLWFYYVILGIITTASFCSWLLRM 323
The following BLAST results are available for this feature:
BLAST of Innexin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
inx-55.628e-2128.48Innexin-5 [Source:UniProtKB/Swiss-Prot;Acc:Q23027... [more]
eat-53.440e-1923.03Innexin eat-5 [Source:UniProtKB/Swiss-Prot;Acc:Q2... [more]
eat-53.440e-1923.03Innexin eat-5 [Source:UniProtKB/Swiss-Prot;Acc:Q2... [more]
inx-31.531e-1723.42Innexin-3 [Source:UniProtKB/Swiss-Prot;Acc:Q19746... [more]
inx-185.000e-1626.28Innexin [Source:UniProtKB/TrEMBL;Acc:Q8MXG8][more]
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BLAST of Innexin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q23027|INX5_CAEEL5.717e-2028.48Innexin-5 OS=Caenorhabditis elegans OX=6239 GN=inx... [more]
sp|Q27295|EAT5_CAEEL3.495e-1823.03Innexin eat-5 OS=Caenorhabditis elegans OX=6239 GN... [more]
sp|Q19746|INX3_CAEEL1.555e-1623.42Innexin-3 OS=Caenorhabditis elegans OX=6239 GN=inx... [more]
sp|O61787|INX16_CAEEL1.280e-1321.52Innexin-16 OS=Caenorhabditis elegans OX=6239 GN=in... [more]
sp|Q23157|INX11_CAEEL2.999e-1323.18Innexin-11 OS=Caenorhabditis elegans OX=6239 GN=in... [more]
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BLAST of Innexin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1I8IJF72.647e-2726.44Innexin OS=Macrostomum lignano OX=282301 GN=inx PE... [more]
A0A1I8HVQ83.201e-2726.44Innexin OS=Macrostomum lignano OX=282301 GN=inx PE... [more]
A0A1I8GM505.039e-2726.44Innexin OS=Macrostomum lignano OX=282301 GN=inx PE... [more]
A0A158R8192.075e-2628.25Innexin OS=Taenia asiatica OX=60517 GN=inx PE=3 SV... [more]
A0A4S2LLY48.981e-2627.91Innexin OS=Opisthorchis felineus OX=147828 GN=inx ... [more]
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BLAST of Innexin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000000713.11.779e-157100.00SMESG000000713.1[more]
SMESG000035987.15.175e-3130.12SMESG000035987.1[more]
SMESG000046667.12.464e-2627.87SMESG000046667.1[more]
SMESG000046667.12.546e-2627.87SMESG000046667.1[more]
SMESG000048374.11.077e-2528.57SMESG000048374.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30018935 ID=SMED30018935|Name=Innexin|organism=Schmidtea mediterranea sexual|type=transcript|length=1001bp
CACGCATCAGTTAATTTTTTTTTTATCAGCAAATTTCTCGTGAAACTTTT
TCTATGTTGTCAATTATTCATTTCGGATTTAGATTTTTCAAAGAAAAATT
TCATCGAAATAATTTTCCCAATGATTTGATTGATGAATATTTTGCAAAGA
TTTTACCGATTATGTTCTTGTTATTTGCAATAATTTTGACAACAAAAGAT
TACATATTCCAGAATCTGGTTTGTGTTATTCCCAAATTATGGATTAGGGC
ACATGAAGAATATAGCAAGGCAATGTGCTGGGCAGATAGCACTTATTTTA
TGAATATAAATAATAAATCCCCTGCCAATAATCAAGAGCTTGATAAATTG
AAAATAAAGTACTATCAATATGTTCCGTTATTTATTGTATGCTTGGCAGT
TGGTTTGATAATTCCTCGAAACGTTTGGAAATTATTTTGTGGACCTTTAG
GAATAGATATCATTCACACTATTGAAATATTTTCTACGCTCTCTCAGTAC
GGAACTAAAAACCAAAGAAAGATCATAATATATATCGAAAATAAAATTTG
TTCAAATCTCAAATAATATCAAGAGAAGACTCGAGGGCTAATTTTGTTAA
ATCAAATAAAAGAAATGGAAGATTTCTTCCTCACATTGTTTTCTATATTG
TTCTAAAATTATTTTACATAGGTTTGGCGATTGGAGAAATATTTCTGATC
CAAATCTTTCTTGGAATGAAAAACATCTATTTCCCAATTCAGATGTTCCT
GAATTCGTCTAGAAACATTGAATGGTCTACAACTGGAAATTTCCCAATAG
TGACTTGGTGCCGAATATTGATCAAGGACAACAGGGATAATTATGCCCGA
AATATCCAATGCACCTTGCCTTGGAATACAGTGCACGATAAATTATTTAT
TATCATTTGGATGTCATTGGTCGTTGGAATTGTTTTAATGTGCTTCAATA
TCTCATATTGGATAATTGAAATTTTTTGTCCCTCACAGCAGAAACTTTTC
A
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protein sequence of SMED30018935-orf-1

>SMED30018935-orf-1 ID=SMED30018935-orf-1|Name=SMED30018935-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=171bp
MLSIIHFGFRFFKEKFHRNNFPNDLIDEYFAKILPIMFLLFAIILTTKDY
IFQNLVCVIPKLWIRAHEEYSKAMCWADSTYFMNINNKSPANNQELDKLK
IKYYQYVPLFIVCLAVGLIIPRNVWKLFCGPLGIDIIHTIEIFSTLSQYG
TKNQRKIIIYIENKICSNLK*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: cellular component
TermDefinition
GO:0005886plasma membrane
GO:0005921gap junction
GO:0016020membrane
GO:0016021integral component of membrane
GO:0030054cell junction
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000043dorsal ventral margin of the whole animal
PLANA:0002032epidermal cell
Vocabulary: INTERPRO
TermDefinition
IPR000990Innexin
Vocabulary: biological process
TermDefinition
GO:0006810transport
GO:0006811ion transport