Insulin like growth factor 2 receptor

Overview
NameInsulin like growth factor 2 receptor
Smed IDSMED30018829
Length (bp)1479
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Insulin like growth factor 2 receptor (SMED30018829) t-SNE clustered cells

Violin plots show distribution of expression levels for Insulin like growth factor 2 receptor (SMED30018829) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Insulin like growth factor 2 receptor (SMED30018829) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Insulin like growth factor 2 receptor (SMED30018829) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30018829

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 3

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
parapharyngeal regionSMED30018829h1SMcG0003576 SmedASXL_013654SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
pharynxSMED30018829h1SMcG0003576 dd_Smed_v4_14729_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cilated neuronSMED30018829h1SMcG0003576 dd_Smed_v4_14729_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Insulin like growth factor 2 receptor vs. Ensembl Human
Match: MMP2 (matrix metallopeptidase 2 [Source:HGNC Symbol;Acc:HGNC:7166])

HSP 1 Score: 58.151 bits (139), Expect = 2.323e-8
Identity = 51/212 (24.06%), Postives = 80/212 (37.74%), Query Frame = 1 
Query:   70 LPSNSTIEMRVKTVNDKFCFFPFVYKNQTFDDCIPYA-STGSKFCPTTCNLESDNELSLCRWEKKNLLEPSCVNLTNSQPYREPSTVTNESCIFPFVYKNKCYNDCIT---LDSYQLWCGATESSDLNPTQYAVCYYNRTQSDEKGCENLKNAKPSIQPETVSNGT----CTFPFVYQENCYEDCV----PDEEPWCSFTKGYKIN-EFGYC 666
            L     + ++    + ++C FPF++  + ++ C     S G  +C TT N E D +   C  E                 +        + C FPF ++   Y+ C T    D Y+ WCG TE  D +  +Y  C                   P     TV   +    C FPF +  N YE C      D + WC+ T  Y  + ++G+C
Sbjct:  165 LGEGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEAL---------------FTMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYR-WCGTTEDYDRD-KKYGFC-------------------PETAMSTVGGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFC 340
[Close]
BLAST of Insulin like growth factor 2 receptor vs. Ensembl Human
Match: MMP2 (matrix metallopeptidase 2 [Source:HGNC Symbol;Acc:HGNC:7166])

HSP 1 Score: 58.151 bits (139), Expect = 2.516e-8
Identity = 51/212 (24.06%), Postives = 80/212 (37.74%), Query Frame = 1 
Query:   70 LPSNSTIEMRVKTVNDKFCFFPFVYKNQTFDDCIPYA-STGSKFCPTTCNLESDNELSLCRWEKKNLLEPSCVNLTNSQPYREPSTVTNESCIFPFVYKNKCYNDCIT---LDSYQLWCGATESSDLNPTQYAVCYYNRTQSDEKGCENLKNAKPSIQPETVSNGT----CTFPFVYQENCYEDCV----PDEEPWCSFTKGYKIN-EFGYC 666
            L     + ++    + ++C FPF++  + ++ C     S G  +C TT N E D +   C  E                 +        + C FPF ++   Y+ C T    D Y+ WCG TE  D +  +Y  C                   P     TV   +    C FPF +  N YE C      D + WC+ T  Y  + ++G+C
Sbjct:  139 LGEGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEAL---------------FTMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYR-WCGTTEDYDRD-KKYGFC-------------------PETAMSTVGGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFC 314
[Close]
BLAST of Insulin like growth factor 2 receptor vs. Ensembl Human
Match: MMP2 (matrix metallopeptidase 2 [Source:HGNC Symbol;Acc:HGNC:7166])

HSP 1 Score: 58.151 bits (139), Expect = 2.516e-8
Identity = 51/212 (24.06%), Postives = 80/212 (37.74%), Query Frame = 1 
Query:   70 LPSNSTIEMRVKTVNDKFCFFPFVYKNQTFDDCIPYA-STGSKFCPTTCNLESDNELSLCRWEKKNLLEPSCVNLTNSQPYREPSTVTNESCIFPFVYKNKCYNDCIT---LDSYQLWCGATESSDLNPTQYAVCYYNRTQSDEKGCENLKNAKPSIQPETVSNGT----CTFPFVYQENCYEDCV----PDEEPWCSFTKGYKIN-EFGYC 666
            L     + ++    + ++C FPF++  + ++ C     S G  +C TT N E D +   C  E                 +        + C FPF ++   Y+ C T    D Y+ WCG TE  D +  +Y  C                   P     TV   +    C FPF +  N YE C      D + WC+ T  Y  + ++G+C
Sbjct:  139 LGEGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEAL---------------FTMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYR-WCGTTEDYDRD-KKYGFC-------------------PETAMSTVGGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFC 314
[Close]
BLAST of Insulin like growth factor 2 receptor vs. Ensembl Human
Match: MMP2 (matrix metallopeptidase 2 [Source:HGNC Symbol;Acc:HGNC:7166])

HSP 1 Score: 57.7658 bits (138), Expect = 3.368e-8
Identity = 51/212 (24.06%), Postives = 80/212 (37.74%), Query Frame = 1 
Query:   70 LPSNSTIEMRVKTVNDKFCFFPFVYKNQTFDDCIPYA-STGSKFCPTTCNLESDNELSLCRWEKKNLLEPSCVNLTNSQPYREPSTVTNESCIFPFVYKNKCYNDCIT---LDSYQLWCGATESSDLNPTQYAVCYYNRTQSDEKGCENLKNAKPSIQPETVSNGT----CTFPFVYQENCYEDCV----PDEEPWCSFTKGYKIN-EFGYC 666
            L     + ++    + ++C FPF++  + ++ C     S G  +C TT N E D +   C  E                 +        + C FPF ++   Y+ C T    D Y+ WCG TE  D +  +Y  C                   P     TV   +    C FPF +  N YE C      D + WC+ T  Y  + ++G+C
Sbjct:  215 LGEGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEAL---------------FTMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYR-WCGTTEDYDRD-KKYGFC-------------------PETAMSTVGGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFC 390
[Close]
BLAST of Insulin like growth factor 2 receptor vs. Ensembl Human
Match: ELSPBP1 (epididymal sperm binding protein 1 [Source:HGNC Symbol;Acc:HGNC:14417])

HSP 1 Score: 52.7582 bits (125), Expect = 9.383e-8
Identity = 41/160 (25.62%), Postives = 64/160 (40.00%), Query Frame = 1 
Query:  124 CFFPFVYKNQTFDDCIPYAS-TGSKFCPTTCNLESDNELSLCRWEKKNLLEPSCVNLTNSQPYREPSTVTNESCIFPFVYKNKCYNDCITLDSYQLWCGATESSDLNPTQYAVCYYNRTQSDEKGCENLKNAKPSIQPETVSNGTCTFPFVYQENCYEDC 600
            C FPF+Y+ + ++ CI   S  GS +C  T   +   +   C             N       R+P       CIFP +Y+N   +DC+  +S +LWC  TE+ D +  +++ C   R  +                   V    C FPF Y+   Y +C
Sbjct:   28 CIFPFIYRGKAYNSCISQGSFLGSLWCSVTSVFDEKQQWKFCE-----------TNEYGGNSLRKP-------CIFPSIYRNNVVSDCMEDESNKLWCPTTENMDKD-GKWSFCADTRISA------------------LVPGFPCHFPFNYKNKNYFNC 150

HSP 2 Score: 51.2174 bits (121), Expect = 3.955e-7
Identity = 36/103 (34.95%), Postives = 51/103 (49.51%), Query Frame = 1 
Query:  340 CIFPFVYKNKCYNDCITLDSY--QLWCGATESSDLNPTQYAVCYYNRTQSDEKGCENLKNAKPSIQPETVSNGTCTFPFVYQENCYEDCVPDE--EPWCSFTK 636
            CIFPF+Y+ K YN CI+  S+   LWC  T   D    Q+  C     +++E G  +L+  KP           C FP +Y+ N   DC+ DE  + WC  T+
Sbjct:   28 CIFPFIYRGKAYNSCISQGSFLGSLWCSVTSVFD-EKQQWKFC-----ETNEYGGNSLR--KP-----------CIFPSIYRNNVVSDCMEDESNKLWCPTTE 111
[Close]
BLAST of Insulin like growth factor 2 receptor vs. Ensembl Zebrafish
Match: mmp9 (matrix metallopeptidase 9 [Source:ZFIN;Acc:ZDB-GENE-040426-2132])

HSP 1 Score: 55.0694 bits (131), Expect = 1.612e-7
Identity = 51/208 (24.52%), Postives = 78/208 (37.50%), Query Frame = 1 
Query:   70 LPSNSTIEMRVKTVNDKFCFFPFVYKNQTFDDCIPYAST-GSKFCPTTCNLESDNELSLCRWEKKNLLEPSCVNLTNSQPYREPSTVTNESCIFPFVYKNKCYNDCITL---DSYQLWCGATESSDLNPTQYAVCYYNRTQSDEKGCENLKNAKPSIQPETVSNGTCTFPFVYQENCYEDCVP----DEEPWCSFTKGYKIN-EFGYC 666
            L S   I+ R        C FPF+++  ++  C     T G  +C TT + + D +   C         PS +  T      E        C+FPF++  K Y+ C T    D Y+ WC  T + D +  +Y  C                N   ++         C FPF +  N Y  C      D + WC  T  Y  + ++G+C
Sbjct:  213 LGSGPAIQTRYGNAEGAMCHFPFLFEGTSYSTCTTEGRTDGLPWCSTTADYDKDKKFGFC---------PSELLFTFDGNSNE------APCVFPFIFDGKKYDSCTTEGRNDGYR-WCSTTANFDTD-KKYGFC---------------PNRDTAVIGGNSEGEPCHFPFTFLGNTYSSCTSEGRNDGKLWCGTTSNYDTDKKWGFC 388
[Close]
BLAST of Insulin like growth factor 2 receptor vs. Ensembl Zebrafish
Match: mmp2 (matrix metallopeptidase 2 [Source:ZFIN;Acc:ZDB-GENE-030131-9123])

HSP 1 Score: 51.2174 bits (121), Expect = 2.271e-6
Identity = 48/208 (23.08%), Postives = 77/208 (37.02%), Query Frame = 1 
Query:   70 LPSNSTIEMRVKTVNDKFCFFPFVYKNQTFDDCIPYA-STGSKFCPTTCNLESDNELSLCRWEKKNLLEPSCVNLTNSQPYREPSTVTNESCIFPFVYKNKCYNDCITL---DSYQLWCGATESSDLNPTQYAVCYYNRTQSDEKGCENLKNAKPSIQPETVSNGTCTFPFVYQENCYEDCVP----DEEPWCSFTKGYKIN-EFGYC 666
            L     ++++      +FC FPF++  + ++ C       G  +C TT N + D +   C  E   LL            +          C FPF ++   Y+ C T    D Y+ WC  TE  D + T Y  C                    S          C FPF +  + Y+ C      D + WC+ TK +  + ++G+C
Sbjct:  215 LGEGQVVKVKYGNAEGEFCKFPFLFMGKEYNSCTSQGRDDGFLWCSTTYNFDDDGKYGFCPHE---LL------------FTLGGNADGAPCKFPFTFQGDKYDSCTTSGRDDGYR-WCATTEDYDKDKT-YGFC---------------PETAMSTSGGNSDGAPCVFPFKFLGDSYDSCTTSGRNDGKMWCAVTKSFDDDRKWGFC 390
[Close]
BLAST of Insulin like growth factor 2 receptor vs. Ensembl Xenopus
Match: mmp9.1 (matrix metallopeptidase 9 gene 2 [Source:NCBI gene;Acc:100494738])

HSP 1 Score: 56.9954 bits (136), Expect = 4.834e-8
Identity = 53/208 (25.48%), Postives = 78/208 (37.50%), Query Frame = 1 
Query:   70 LPSNSTIEMRVKTVNDKFCFFPFVYKNQTFDDCIPYA-STGSKFCPTTCNLESDNELSLCRWEKKNLLEPSCVNLTNSQPYREPSTVTNESCIFPFVYKNKCYNDCITLDSYQ---LWCGATESSDLNPTQYAVCYYNRTQSDEKGCENLKNAKPSIQPETVSNGTCTFPFVYQENCYEDCV----PDEEPWCSFTKGY-KINEFGYC 666
            L + + ++ R        C FPFV+  Q+++ C     S G  +C TT N + D +   C  E   LL            Y        E C FPF++    Y+ C T D  Q    WCG T + D +  +Y  C                N   S+         C FPF +    Y  C      D + WC+ T  Y +  ++G+C
Sbjct:  214 LGTGTVVKTRFGNAGGAQCHFPFVFDGQSYNSCTSDGRSDGLPWCSTTPNFDQDKKYGFCPSE---LL------------YTYGGNSDGEPCTFPFIFDGVSYDGC-TKDGRQDGYRWCGTTANYDQD-HKYGFC---------------PNRDISVIGGNSQGDPCVFPFTFLGKRYNSCTSEGRSDRKLWCATTSSYDRDKKWGFC 389
[Close]
BLAST of Insulin like growth factor 2 receptor vs. Ensembl Xenopus
Match: mmp9.1 (matrix metallopeptidase 9 gene 2 [Source:NCBI gene;Acc:100494738])

HSP 1 Score: 56.9954 bits (136), Expect = 5.583e-8
Identity = 52/208 (25.00%), Postives = 78/208 (37.50%), Query Frame = 1 
Query:   70 LPSNSTIEMRVKTVNDKFCFFPFVYKNQTFDDCIPYA-STGSKFCPTTCNLESDNELSLCRWEKKNLLEPSCVNLTNSQPYREPSTVTNESCIFPFVYKNKCYNDCIT---LDSYQLWCGATESSDLNPTQYAVCYYNRTQSDEKGCENLKNAKPSIQPETVSNGTCTFPFVYQENCYEDCV----PDEEPWCSFTKGY-KINEFGYC 666
            L + + ++ R        C FPFV+  Q+++ C     S G  +C TT N + D +   C  E   LL            Y        E C FPF++    Y+ C      D Y+ WCG T + D +  +Y  C                N   S+         C FPF +    Y  C      D + WC+ T  Y +  ++G+C
Sbjct:  223 LGTGTVVKTRFGNAGGAQCHFPFVFDGQSYNSCTSDGRSDGLPWCSTTPNFDQDKKYGFCPSE---LL------------YTYGGNSDGEPCTFPFIFDGVSYDGCTKDGRQDGYR-WCGTTANYDQD-HKYGFC---------------PNRDISVIGGNSQGDPCVFPFTFLGKRYNSCTSEGRSDRKLWCATTSSYDRDKKWGFC 398
[Close]
BLAST of Insulin like growth factor 2 receptor vs. Ensembl Xenopus
Match: mmp9.1 (matrix metallopeptidase 9 gene 2 [Source:NCBI gene;Acc:100494738])

HSP 1 Score: 56.6102 bits (135), Expect = 6.461e-8
Identity = 53/208 (25.48%), Postives = 78/208 (37.50%), Query Frame = 1 
Query:   70 LPSNSTIEMRVKTVNDKFCFFPFVYKNQTFDDCIPYA-STGSKFCPTTCNLESDNELSLCRWEKKNLLEPSCVNLTNSQPYREPSTVTNESCIFPFVYKNKCYNDCITLDSYQ---LWCGATESSDLNPTQYAVCYYNRTQSDEKGCENLKNAKPSIQPETVSNGTCTFPFVYQENCYEDCV----PDEEPWCSFTKGY-KINEFGYC 666
            L + + ++ R        C FPFV+  Q+++ C     S G  +C TT N + D +   C  E   LL            Y        E C FPF++    Y+ C T D  Q    WCG T + D +  +Y  C                N   S+         C FPF +    Y  C      D + WC+ T  Y +  ++G+C
Sbjct:  220 LGTGTVVKTRFGNAGGAQCHFPFVFDGQSYNSCTSDGRSDGLPWCSTTPNFDQDKKYGFCPSE---LL------------YTYGGNSDGEPCTFPFIFDGVSYDGC-TKDGRQDGYRWCGTTANYDQD-HKYGFC---------------PNRDISVIGGNSQGDPCVFPFTFLGKRYNSCTSEGRSDRKLWCATTSSYDRDKKWGFC 395
[Close]
BLAST of Insulin like growth factor 2 receptor vs. Ensembl Xenopus
Match: mmp9.1 (matrix metallopeptidase 9 gene 2 [Source:NCBI gene;Acc:100494738])

HSP 1 Score: 55.8398 bits (133), Expect = 1.095e-7
Identity = 64/288 (22.22%), Postives = 103/288 (35.76%), Query Frame = 1 
Query:   70 LPSNSTIEMRVKTVNDKFCFFPFVYKNQTFDDCIPYA-STGSKFCPTTCNLESDNELSLCRWEKKNLLEPSCVNLTNSQPYREPSTVTNESCIFPFVYKNKCYNDCI---TLDSYQLWCGATESSDLNPTQYAVCYYNRTQSDEKGCENLKNAKPSIQPETVSNGTCTFPFVYQ----ENCYEDCVPDEEPWCSFT--------------KGYKI-----NEFGYCKYLRSFQKWRSLWKSSGSIANNLKLHCSNRSRKHEISG**MGSFTST*Q-FNYNQIAKNVPN 849
            L + + ++ R        C FPF++  Q++  C     S G  +C TT + + D +   C  E   LL            Y        + C+FPF++    YN C      D Y+ WC  T   D +  +Y  C                N   ++         C FPF +Q     +C  D   D + WC+ T              +GY +     +EFG+   L   +   +L     S   + +LH  +      + G  MGS       + +NQ ++  PN
Sbjct:  213 LGTGTVVKTRFGNAEGALCHFPFIFDGQSYSSCTTSGRSDGLPWCSTTPSYDQDKKYGFCPSE---LL------------YTYGGNSEGQPCVFPFIFDGVSYNGCTKEGRQDGYR-WCSTTADYDQD-QKYGFC---------------PNRDTAVIGGNSQGEPCVFPFTFQGKRFNSCTTDGRDDRKLWCATTSSYDQDRKWGFCPDQGYSLFLVAAHEFGHALGLEHSEVQDALMYPMYSYVKDFQLHEDDVRGIQYLYGTGMGSIMPPGVCYTFNQGSRPNPN 468
[Close]
BLAST of Insulin like growth factor 2 receptor vs. Ensembl Xenopus
Match: mmp9.1 (matrix metallopeptidase 9 gene 2 [Source:NCBI gene;Acc:100494738])

HSP 1 Score: 55.0694 bits (131), Expect = 2.319e-7
Identity = 49/208 (23.56%), Postives = 78/208 (37.50%), Query Frame = 1 
Query:   70 LPSNSTIEMRVKTVNDKFCFFPFVYKNQTFDDCIPYA-STGSKFCPTTCNLESDNELSLCRWEKKNLLEPSCVNLTNSQPYREPSTVTNESCIFPFVYKNKCYNDCI---TLDSYQLWCGATESSDLNPTQYAVCYYNRTQSDEKGCENLKNAKPSIQPETVSNGTCTFPFVYQ----ENCYEDCVPDEEPWCSFTKGY-KINEFGYC 666
            L + + ++ R        C FPF++  Q++  C     S G  +C TT + + D +   C  E   LL            Y        + C+FPF++    YN C      D Y+ WC  T   D +  +Y  C                N   ++         C FPF +Q     +C  D   D + WC+ T  Y +  ++G+C
Sbjct:  161 LGTGTVVKTRFGNAEGALCHFPFIFDGQSYSSCTTSGRSDGLPWCSTTPSYDQDKKYGFCPSE---LL------------YTYGGNSEGQPCVFPFIFDGVSYNGCTKEGRQDGYR-WCSTTADYDQD-QKYGFC---------------PNRDTAVIGGNSQGEPCVFPFTFQGKRFNSCTTDGRDDRKLWCATTSSYDQDRKWGFC 336
[Close]
BLAST of Insulin like growth factor 2 receptor vs. Ensembl Mouse
Match: Mmp2 (matrix metallopeptidase 2 [Source:MGI Symbol;Acc:MGI:97009])

HSP 1 Score: 58.5362 bits (140), Expect = 1.156e-8
Identity = 63/268 (23.51%), Postives = 96/268 (35.82%), Query Frame = 1 
Query:   70 LPSNSTIEMRVKTVNDKFCFFPFVYKNQTFDDCIPYA-STGSKFCPTTCNLESDNELSLCRWEKKNLLEPSCVNLTNSQPYREPSTVTNESCIFPFVYKNKCYNDCIT---LDSYQLWCGATESSDLNPTQYAVCYYNRTQSDEKGCENLKNAKPSIQPETVSNGT----CTFPFVYQENCYEDCVP----DEEPWCSFT--------------KGYKI-----NEFGYCKYLRSFQKWRSLWKSSGSIANNLKLHCSNRSRKHEISG 780
            L     + ++    + ++C FPF++  + +  C     S G  +C TT N E D +   C  E    +  +     + QP           C FPF ++   YN C T    D Y+ WCG TE  D +  +Y  C                   P     TV   +    C FPF +  N YE C      D + WC+ T              +GY +     +EFG+   L   Q   +L     +   N +L   +     E+ G
Sbjct:  215 LGEGQVVRVKYGNADGEYCKFPFLFNGREYSSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNA----DGQP-----------CKFPFRFQGTSYNSCTTEGRTDGYR-WCGTTEDYDRD-KKYGFC-------------------PETAMSTVGGNSEGAPCVFPFTFLGNKYESCTSAGRNDGKVWCATTTNYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKNFRLSHDDIKGIQELYG 446
[Close]
BLAST of Insulin like growth factor 2 receptor vs. Ensembl Mouse
Match: Mmp9 (matrix metallopeptidase 9 [Source:MGI Symbol;Acc:MGI:97011])

HSP 1 Score: 51.2174 bits (121), Expect = 2.421e-6
Identity = 47/199 (23.62%), Postives = 77/199 (38.69%), Query Frame = 1 
Query:  112 NDKFCFFPFVYKNQTFDDCIPYA-STGSKFCPTTCNLESDNELSLCRWEKKNLLEPSCVNLTNSQPYREPSTVTNESCIFPFVYKNKCYNDCITL---DSYQLWCGATESSDLNPTQYAVCYYNRTQSDEKGCENLKNAKPSIQPETVSNG-----TCTFPFVYQENCYEDCVPDEEP----WCSFTKGYKIN-EFGYC 666
            N   C FPF ++ +++  C     + G+ +C TT + + D +   C  E+                Y E      + C+FPF+++ + Y+ C T    D Y+ WC  T + D +   Y  C                   P+    TV  G      C FPFV+    Y  C  D       WC+ T  +  + ++G+C
Sbjct:  226 NGAPCHFPFTFEGRSYSACTTDGRNDGTPWCSTTADYDKDGKFGFCPSERL---------------YTEHGNGEGKPCVFPFIFEGRSYSACTTKGRSDGYR-WCATTANYDQD-KLYGFC-------------------PTRVDATVVGGNSAGELCVFPFVFLGKQYSSCTSDGRRDGRLWCATTSNFDTDKKWGFC 388
[Close]
BLAST of Insulin like growth factor 2 receptor vs. UniProt/SwissProt
Match: sp|P33434|MMP2_MOUSE (72 kDa type IV collagenase OS=Mus musculus OX=10090 GN=Mmp2 PE=1 SV=1)

HSP 1 Score: 58.5362 bits (140), Expect = 8.084e-8
Identity = 63/268 (23.51%), Postives = 96/268 (35.82%), Query Frame = 1 
Query:   70 LPSNSTIEMRVKTVNDKFCFFPFVYKNQTFDDCIPYA-STGSKFCPTTCNLESDNELSLCRWEKKNLLEPSCVNLTNSQPYREPSTVTNESCIFPFVYKNKCYNDCIT---LDSYQLWCGATESSDLNPTQYAVCYYNRTQSDEKGCENLKNAKPSIQPETVSNGT----CTFPFVYQENCYEDCVP----DEEPWCSFT--------------KGYKI-----NEFGYCKYLRSFQKWRSLWKSSGSIANNLKLHCSNRSRKHEISG 780
            L     + ++    + ++C FPF++  + +  C     S G  +C TT N E D +   C  E    +  +     + QP           C FPF ++   YN C T    D Y+ WCG TE  D +  +Y  C                   P     TV   +    C FPF +  N YE C      D + WC+ T              +GY +     +EFG+   L   Q   +L     +   N +L   +     E+ G
Sbjct:  215 LGEGQVVRVKYGNADGEYCKFPFLFNGREYSSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNA----DGQP-----------CKFPFRFQGTSYNSCTTEGRTDGYR-WCGTTEDYDRD-KKYGFC-------------------PETAMSTVGGNSEGAPCVFPFTFLGNKYESCTSAGRNDGKVWCATTTNYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKNFRLSHDDIKGIQELYG 446
[Close]
BLAST of Insulin like growth factor 2 receptor vs. UniProt/SwissProt
Match: sp|P33436|MMP2_RAT (72 kDa type IV collagenase OS=Rattus norvegicus OX=10116 GN=Mmp2 PE=1 SV=2)

HSP 1 Score: 58.151 bits (139), Expect = 1.125e-7
Identity = 54/212 (25.47%), Postives = 82/212 (38.68%), Query Frame = 1 
Query:   70 LPSNSTIEMRVKTVNDKFCFFPFVYKNQTFDDCIPYA-STGSKFCPTTCNLESDNELSLCRWEKKNLLEPSCVNLTNSQPYREPSTVTNESCIFPFVYKNKCYNDCIT---LDSYQLWCGATESSDLNPTQYAVCYYNRTQSDEKGCENLKNAKPSIQPETVSNGT----CTFPFVYQENCYEDCV----PDEEPWCSFTKGYKIN-EFGYC 666
            L     + ++    + ++C FPF++  + +  C     S G  +C TT N E D +   C  E    +  +     + QP           C FPF ++   YN C T    D Y+ WCG TE  D +  +Y  C                   P     TV   +    C FPF +  N YE C      D + WC+ T  Y  + ++G+C
Sbjct:  215 LGEGQVVRVKYGNADGEYCKFPFLFNGREYSSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGN----GDGQP-----------CKFPFRFQGTSYNSCTTEGRTDGYR-WCGTTEDYDRD-KKYGFC-------------------PETAMSTVGGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKVWCATTTNYDDDRKWGFC 390
[Close]
BLAST of Insulin like growth factor 2 receptor vs. UniProt/SwissProt
Match: sp|P08253|MMP2_HUMAN (72 kDa type IV collagenase OS=Homo sapiens OX=9606 GN=MMP2 PE=1 SV=2)

HSP 1 Score: 57.7658 bits (138), Expect = 1.617e-7
Identity = 51/212 (24.06%), Postives = 80/212 (37.74%), Query Frame = 1 
Query:   70 LPSNSTIEMRVKTVNDKFCFFPFVYKNQTFDDCIPYA-STGSKFCPTTCNLESDNELSLCRWEKKNLLEPSCVNLTNSQPYREPSTVTNESCIFPFVYKNKCYNDCIT---LDSYQLWCGATESSDLNPTQYAVCYYNRTQSDEKGCENLKNAKPSIQPETVSNGT----CTFPFVYQENCYEDCV----PDEEPWCSFTKGYKIN-EFGYC 666
            L     + ++    + ++C FPF++  + ++ C     S G  +C TT N E D +   C  E                 +        + C FPF ++   Y+ C T    D Y+ WCG TE  D +  +Y  C                   P     TV   +    C FPF +  N YE C      D + WC+ T  Y  + ++G+C
Sbjct:  215 LGEGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEAL---------------FTMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYR-WCGTTEDYDRD-KKYGFC-------------------PETAMSTVGGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFC 390
[Close]
BLAST of Insulin like growth factor 2 receptor vs. UniProt/SwissProt
Match: sp|P50757|MMP2_RABIT (72 kDa type IV collagenase OS=Oryctolagus cuniculus OX=9986 GN=MMP2 PE=2 SV=1)

HSP 1 Score: 55.0694 bits (131), Expect = 1.065e-6
Identity = 60/268 (22.39%), Postives = 96/268 (35.82%), Query Frame = 1 
Query:   70 LPSNSTIEMRVKTVNDKFCFFPFVYKNQTFDDCIPYA-STGSKFCPTTCNLESDNELSLCRWEKKNLLEPSCVNLTNSQPYREPSTVTNESCIFPFVYKNKCYNDCIT---LDSYQLWCGATESSDLNPTQYAVCYYNRTQSDEKGCENLKNAKPSIQPETVSNGT----CTFPFVYQENCYEDCV----PDEEPWCSFT--------------KGYKI-----NEFGYCKYLRSFQKWRSLWKSSGSIANNLKLHCSNRSRKHEISG 780
            L     + ++    + ++C FPF++  + +  C     S G  +C TT N E D +   C  E    +  +     + QP           C FPF ++   Y+ C T    D Y+ WCG TE  D +  +Y  C                   P     T+   +    C FPF +  N YE C      D + WC+ +              +GY +     +EFG+   L   Q   +L     +   N +L   +     E+ G
Sbjct:  215 LGEGQVVRVKYGNADGEYCKFPFLFNGKEYTSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNA----DGQP-----------CKFPFRFQGTSYSSCTTEGRTDGYR-WCGTTEDYDRD-KKYGFC-------------------PETAMSTIGGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCATSTNYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKNFRLSQDDIKGIQELYG 446
[Close]
BLAST of Insulin like growth factor 2 receptor vs. UniProt/SwissProt
Match: sp|Q96BH3|ESPB1_HUMAN (Epididymal sperm-binding protein 1 OS=Homo sapiens OX=9606 GN=ELSPBP1 PE=1 SV=2)

HSP 1 Score: 52.7582 bits (125), Expect = 1.532e-6
Identity = 44/178 (24.72%), Postives = 70/178 (39.33%), Query Frame = 1 
Query:  124 CFFPFVYKNQTFDDCIPYAS-TGSKFCPTTCNLESDNELSLCRWEKKNLLEPSCVNLTNSQPYREPSTVTNESCIFPFVYKNKCYNDCITLDSYQLWCGATESSDLNPTQYAVCYYNRTQSDEKGCENLKNAKPSIQPETVSNGTCTFPFVYQENCYEDCVPDEEP----WCSFTKGY 642
            C FPF+Y+ + ++ CI   S  GS +C  T   +   +   C             N       R+P       CIFP +Y+N   +DC+  +S +LWC  TE+ D +  +++ C   R  +                   V    C FPF Y+   Y +C  +       WC+ +  Y
Sbjct:   74 CIFPFIYRGKAYNSCISQGSFLGSLWCSVTSVFDEKQQWKFCE-----------TNEYGGNSLRKP-------CIFPSIYRNNVVSDCMEDESNKLWCPTTENMDKD-GKWSFCADTRISA------------------LVPGFPCHFPFNYKNKNYFNCTNEGSKENLVWCATSYNY 214
[Close]
BLAST of Insulin like growth factor 2 receptor vs. TrEMBL
Match: A0A1I8GD55 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 110.538 bits (275), Expect = 1.113e-21
Identity = 68/230 (29.57%), Postives = 106/230 (46.09%), Query Frame = 1 
Query:  121 FCFFPFVYKNQTFDDCI----------PYASTGSKFC----PTTCNLESDNELSLCRWEKKNLLEPSCVNL----TNSQPYREPSTVTNESCIFPFVYKNKCYNDCITLDSYQLWCGATESSDLNPTQYAVCYYNRTQSDEKGCENLKNAKPSIQPETVSN------------GTCTFPFVYQENCYEDCVPDEEP-----WCSFTKGYKINEFG-YCKYLRSFQKWRSL 702
             CFFPF Y   T++DCI          PY   GS +C     T+CN   D+  + C++   +L + +C  L    T+++P     + +  SC FPF+Y   C+ DC+T  + + WC  T+ ++   + Y  C Y     ++  C +L +A     P  V N            G CTFPF Y+E CY+DC   +       WCS  + Y+ N+    C Y R ++ +  L
Sbjct: 1305 LCFFPFEYSGTTYNDCIGDTSGDPLTSPYCD-GSGYCNYWCATSCNYGLDSMWNYCKFRLSDLAKTNCSALGSATTSAEPLLYGGSGSGTSCYFPFLYNGACHYDCVT-SATEPWCATTDVAEHVSSNYKHCRYTFAGKNDPSCASLSSATTYYIPPQVGNYSISGTLQTDQYGNCTFPFYYKEKCYDDCTTVDATRWYLIWCSTDQYYQPNKMTRVCPYYRKYRTYTGL 1532
[Close]
BLAST of Insulin like growth factor 2 receptor vs. TrEMBL
Match: A0A267E530 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig014498g1 PE=4 SV=1)

HSP 1 Score: 102.064 bits (253), Expect = 4.697e-19
Identity = 75/243 (30.86%), Postives = 108/243 (44.44%), Query Frame = 1 
Query:   67 CLPSNSTIEMRVKTVN-----DKFCFFPFVYKNQTFDDC-IPY--ASTGSKFCPTTCNLESD-NELSLCRWEKKNLLEPSCVNLTNSQPYRE----PSTVTNESCIFPFVYKNKCYNDCITLD-SYQLWCGATESSDLNPTQYAVCYYNRTQSDEKGCENLKNAKPSIQPETVSN-----------GTCTFPFVYQENCYEDCVPDEE-----PWCSFTKGYKINEFG-YCKYLRSFQKWRSL 702
            C P++S  + RV  V+        C+FPF Y  + F +C  PY   S    +C T+CN  +D +    CR+   +L +P+C  L N     E     S+    +C FPF++ N CY+DCI  D S Q WC  T+      T    C   R    +  C  L    P   P+ + N           G CTFPF Y+E CY+DC   +      PWC   K Y+ N+    C + R +++   L
Sbjct:   24 CNPASSVPDPRVGVVDYPGTAGDSCYFPFTYGGRVFHECDGPYCDGSFCGYWCATSCNYPTDYSAWRFCRFMVADLAKPNCAALANMSSSTEIEVYGSSGLGTACYFPFMHDNVCYDDCIDTDGSGQFWCSTTDVMYHVATNKRFCRATRKGLRDSSCSRLNATAPVYLPQQIGNYSIALVQTDPTGNCTFPFYYKEKCYDDCTTVDAQAWDLPWCLTEKYYQPNKRTRVCPHYRKYKEVTGL 266
[Close]
BLAST of Insulin like growth factor 2 receptor vs. TrEMBL
Match: A0A267GYT2 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig014498g2 PE=4 SV=1)

HSP 1 Score: 101.679 bits (252), Expect = 6.826e-19
Identity = 74/243 (30.45%), Postives = 108/243 (44.44%), Query Frame = 1 
Query:   67 CLPSNSTIEMRVKTVN-----DKFCFFPFVYKNQTFDDC-IPY--ASTGSKFCPTTCNLESD-NELSLCRWEKKNLLEPSCVNLTNSQPYRE----PSTVTNESCIFPFVYKNKCYNDCITLD-SYQLWCGATESSDLNPTQYAVCYYNRTQSDEKGCENLKNAKPSIQPETVSN-----------GTCTFPFVYQENCYEDCVPDEE-----PWCSFTKGYKINEFG-YCKYLRSFQKWRSL 702
            C P++S  + RV  V+        C+FPF Y  + F +C  PY   S    +C T+CN  +D +    CR+   +L +P+C  L N     E      + +  +C FPF++ N CY+DCI  D S Q WC  T+      T    C   R    +  C  L    P   P+ + N           G CTFPF Y+E CY+DC   +      PWC   K Y+ N+    C + R +++   L
Sbjct:   21 CNPASSVPDPRVGVVDYPGTAGDSCYFPFTYGGRVFHECDGPYCDGSFCGYWCATSCNYPTDYSAWRFCRFMVADLAKPNCAALANMSSSTEIEVYGGSGSGTACYFPFMHDNVCYDDCIDTDGSGQFWCSTTDVMYHVATNKRFCRATRKGLRDSSCSRLNATAPVYLPQQIGNYSIALVQTDPTGNCTFPFYYKEKCYDDCTTVDAQAWDLPWCLTEKYYQPNKRTRVCPHYRKYKEVTGL 263
[Close]
BLAST of Insulin like growth factor 2 receptor vs. TrEMBL
Match: A0A267FHF8 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig009063g1 PE=4 SV=1)

HSP 1 Score: 98.9821 bits (245), Expect = 5.021e-18
Identity = 68/234 (29.06%), Postives = 107/234 (45.73%), Query Frame = 1 
Query:  109 VNDKFCFFPFVYKNQTFDDCI----------PYASTGSKFC----PTTCNLESDNELSLCRWEKKNLLEPSCVNL----TNSQPYREPSTVTNESCIFPFVYKNKCYNDCITLDSYQLWCGATESSDLNPTQYAVCYYNRTQSDEKGCENLKNAKPSIQPETVSN------------GTCTFPFVYQENCYEDCVPDEEP-----WCSFTKGYKINEFG-YCKYLRSFQKWRSL 702
             +   CFFPF Y   T++DCI          PY   GS +C     T+CN   D+  + C++   +L + +C  L    T+++P     + +  SC FPF+Y   C+ DC+T  + + WC  T+ ++   + Y  C Y     ++  C +L +A     P  V N            G CTFPF Y+E CY+DC   +       WCS  + Y+ N+    C Y R ++ +  L
Sbjct:  105 TSGTLCFFPFEYSGTTYNDCIGDTSGDPLTSPYCD-GSGYCNYWCATSCNYGLDSMWNYCKFRLSDLAKTNCSALGSATTSAEPLLYGGSGSGTSCYFPFLYNGACHYDCVT-SATEPWCATTDVAEHVSSNYKHCRYTFAGKNDPSCASLSSATTYYIPPQVGNYSISGTLQTDQYGNCTFPFYYKEKCYDDCTTVDATRWYLIWCSTDQYYQPNKMTRVCPYYRKYRTYTGL 336
[Close]
BLAST of Insulin like growth factor 2 receptor vs. TrEMBL
Match: A0A1I8FYL0 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 98.9821 bits (245), Expect = 5.034e-18
Identity = 72/256 (28.12%), Postives = 114/256 (44.53%), Query Frame = 1 
Query:   61 KSCLPSNSTIEMRVK------TVNDKFCFFPFVYKNQTFDDCI----------PYASTGSKFC----PTTCNLESDNELSLCRWEKKNLLEPSCVNL----TNSQPYREPSTVTNESCIFPFVYKNKCYNDCITLDSYQLWCGATESSDLNPTQYAVCYYNRTQSDEKGCENLKNAKPSIQPETVSN------------GTCTFPFVYQENCYEDCVPDEEP-----WCSFTKGYKINEFG-YCKYLRSFQKWRSL 702
             +C P  S    ++K        +   CFFPF Y   T++DCI          PY   GS +C     T+CN   D+  + C++   +L + +C  L    T+++P     + +  SC FPF+Y   C+ DC+T  + + WC  T+ ++   + Y  C Y     ++  C +L +A     P  V N            G CTFPF Y+E CY+DC   +       WCS  + Y+ N+    C Y R ++ +  L
Sbjct:   23 ATCDPVGSKNTTQIKLDPGQTGTSGTLCFFPFEYSGTTYNDCIGDTSGDPLTSPYCD-GSGYCNYWCATSCNYGLDSMWNYCKFRLSDLAKTNCSALGSATTSAEPLLYGGSGSGTSCYFPFLYNGACHYDCVT-SATEPWCATTDVAEHVSSNYKHCRYTFAGKNDPSCASLSSATTYYIPPQVGNYSISGTLQTDQYGNCTFPFYYKEKCYDDCTTVDATRWYLIWCSTDQYYQPNKMTRVCPYYRKYRTYTGL 276
[Close]
BLAST of Insulin like growth factor 2 receptor vs. Ensembl Cavefish
Match: mmp9 (matrix metallopeptidase 9 [Source:ZFIN;Acc:ZDB-GENE-040426-2132])

HSP 1 Score: 55.0694 bits (131), Expect = 1.226e-7
Identity = 49/208 (23.56%), Postives = 79/208 (37.98%), Query Frame = 1 
Query:   70 LPSNSTIEMRVKTVNDKFCFFPFVYKNQTFDDCIPYA-STGSKFCPTTCNLESDNELSLCRWEKKNLLEPSCVNLTNSQPYREPSTVTNESCIFPFVYKNKCYNDCIT---LDSYQLWCGATESSDLNPTQYAVCYYNRTQSDEKGCENLKNAKPSIQPETVSNGTCTFPFVYQENCYEDCV----PDEEPWCSFTKGYKIN-EFGYC 666
            L +   ++ R        C FPF+++  ++  CI    S G  +C TT N ++D +   C         PS +  T               C+FPF ++ + YN C T    D Y+ WC  T + D +  +Y  C                N   ++         C FPF +    Y  C      D + WC+ T  Y  + ++G+C
Sbjct:  213 LGTGPVVKTRYGNGEGALCKFPFIFEGTSYSTCITEGRSDGLPWCATTANYDNDKKFGFC---------PSELLFTFD------GNSNGAECVFPFTFQGETYNGCTTEGRSDGYR-WCATTSNFDTD-KKYGFC---------------PNRDTAVIGGNSEGEPCQFPFTFLGTKYTSCTSEGRGDGKLWCATTSNYDADKKWGFC 388
[Close]
BLAST of Insulin like growth factor 2 receptor vs. Ensembl Cavefish
Match: mmp9 (matrix metallopeptidase 9 [Source:ZFIN;Acc:ZDB-GENE-040426-2132])

HSP 1 Score: 55.0694 bits (131), Expect = 1.345e-7
Identity = 49/208 (23.56%), Postives = 79/208 (37.98%), Query Frame = 1 
Query:   70 LPSNSTIEMRVKTVNDKFCFFPFVYKNQTFDDCIPYA-STGSKFCPTTCNLESDNELSLCRWEKKNLLEPSCVNLTNSQPYREPSTVTNESCIFPFVYKNKCYNDCIT---LDSYQLWCGATESSDLNPTQYAVCYYNRTQSDEKGCENLKNAKPSIQPETVSNGTCTFPFVYQENCYEDCVP----DEEPWCSFTKGYKIN-EFGYC 666
            L +   ++ R        C FPF+++  ++  CI    S G  +C TT N ++D +   C         PS +  T               C+FPF ++ + YN C T    D Y+ WC  T + D +  +Y  C                N   ++         C FPF +    Y  C      D + WC+ T  Y  + ++G+C
Sbjct:  213 LGTGPVVKTRYGNGEGALCKFPFIFEGTSYSTCITEGRSDGLPWCATTANYDNDKKFGFC---------PSELLFTFD------GNSNGAECVFPFTFQGETYNGCTTEGRSDGYR-WCATTSNFDTD-KKYGFC---------------PNRDTAVIGGNSEGEPCQFPFTFLGTKYTSCTSEGRGDGKLWCATTSNYDADKKWGFC 388
[Close]
BLAST of Insulin like growth factor 2 receptor vs. Ensembl Cavefish
Match: mmp9 (matrix metallopeptidase 9 [Source:ZFIN;Acc:ZDB-GENE-040426-2132])

HSP 1 Score: 55.0694 bits (131), Expect = 1.345e-7
Identity = 49/208 (23.56%), Postives = 79/208 (37.98%), Query Frame = 1 
Query:   70 LPSNSTIEMRVKTVNDKFCFFPFVYKNQTFDDCIPYA-STGSKFCPTTCNLESDNELSLCRWEKKNLLEPSCVNLTNSQPYREPSTVTNESCIFPFVYKNKCYNDCIT---LDSYQLWCGATESSDLNPTQYAVCYYNRTQSDEKGCENLKNAKPSIQPETVSNGTCTFPFVYQENCYEDCV----PDEEPWCSFTKGYKIN-EFGYC 666
            L +   ++ R        C FPF+++  ++  CI    S G  +C TT N ++D +   C         PS +  T               C+FPF ++ + YN C T    D Y+ WC  T + D +  +Y  C                N   ++         C FPF +    Y  C      D + WC+ T  Y  + ++G+C
Sbjct:  213 LGTGPVVKTRYGNGEGALCKFPFIFEGTSYSTCITEGRSDGLPWCATTANYDNDKKFGFC---------PSELLFTFD------GNSNGAECVFPFTFQGETYNGCTTEGRSDGYR-WCATTSNFDTD-KKYGFC---------------PNRDTAVIGGNSEGEPCQFPFTFLGTKYTSCTSEGRGDGKLWCATTSNYDADKKWGFC 388
[Close]
BLAST of Insulin like growth factor 2 receptor vs. Ensembl Cavefish
Match: ENSAMXT00000056262.1 (pep primary_assembly:Astyanax_mexicanus-2.0:12:27653848:27683308:-1 gene:ENSAMXG00000008874.2 transcript:ENSAMXT00000056262.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 51.6026 bits (122), Expect = 1.693e-6
Identity = 36/112 (32.14%), Postives = 53/112 (47.32%), Query Frame = 1 
Query:  112 NDKFCFFPFVYKNQTFDDCIPYAST-GSKFCPTTCNLESDNELSLCRWEKKNLLEPSCVNLTNSQPYREPSTVTNESCIFPFVYKNKCYNDCITLDSYQ---LWCGATESSD 435
            N + C FPFV++ +T   CI    T G  +C TT + +SD + S C   ++NL+  +    +N              C FPF+Y  + Y DC T D  +    WCG T + D
Sbjct:  340 NGQPCVFPFVFEGKTHYSCISEGRTDGQLWCSTTSDYDSDGQYSFC--TQRNLMVTTRGGNSN-----------GAMCKFPFIYNGRNYTDC-TADGRRDGMKWCGTTTNYD 437

HSP 2 Score: 49.6766 bits (117), Expect = 6.957e-6
Identity = 36/119 (30.25%), Postives = 51/119 (42.86%), Query Frame = 1 
Query:  331 NESCIFPFVYKNKCYNDCIT--LDSYQLWCGATESSDLNPTQYAVCYYNRTQSDEKGCENLKNAKPSIQPETVSNGTCTFPFVYQENCYEDCVPDEE----PWCSFTKGYKINE-FGYC 666
             + C+FPFV++ K +  CI+      QLWC  T   D +  QY+ C    TQ         +N   + +    +   C FPF+Y    Y DC  D       WC  T  Y   + FG+C
Sbjct:  341 GQPCVFPFVFEGKTHYSCISEGRTDGQLWCSTTSDYDSD-GQYSFC----TQ---------RNLMVTTRGGNSNGAMCKFPFIYNGRNYTDCTADGRRDGMKWCGTTTNYDDEQRFGFC 445
[Close]
BLAST of Insulin like growth factor 2 receptor vs. Ensembl Cavefish
Match: ENSAMXT00000035233.1 (pep primary_assembly:Astyanax_mexicanus-2.0:12:27610513:27683296:-1 gene:ENSAMXG00000008874.2 transcript:ENSAMXT00000035233.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 51.2174 bits (121), Expect = 2.428e-6
Identity = 36/112 (32.14%), Postives = 53/112 (47.32%), Query Frame = 1 
Query:  112 NDKFCFFPFVYKNQTFDDCIPYAST-GSKFCPTTCNLESDNELSLCRWEKKNLLEPSCVNLTNSQPYREPSTVTNESCIFPFVYKNKCYNDCITLDSYQ---LWCGATESSD 435
            N + C FPFV++ +T   CI    T G  +C TT + +SD + S C   ++NL+  +    +N              C FPF+Y  + Y DC T D  +    WCG T + D
Sbjct:  358 NGQPCVFPFVFEGKTHYSCISEGRTDGQLWCSTTSDYDSDGQYSFC--TQRNLMVTTRGGNSN-----------GAMCKFPFIYNGRNYTDC-TADGRRDGMKWCGTTTNYD 455

HSP 2 Score: 50.447 bits (119), Expect = 4.202e-6
Identity = 37/120 (30.83%), Postives = 49/120 (40.83%), Query Frame = 1 
Query:  331 NESCIFPFVYKNKCYNDCIT--LDSYQLWCGATESSDLNPTQYAVCYYNRTQSDEKGCENLKNAKPSIQPETVSNGT-CTFPFVYQENCYEDCVPDEE----PWCSFTKGYKINE-FGYC 666
             + C+FPFV++ K +  CI+      QLWC  T   D +  QY+ C         +G                SNG  C FPF+Y    Y DC  D       WC  T  Y   + FG+C
Sbjct:  359 GQPCVFPFVFEGKTHYSCISEGRTDGQLWCSTTSDYDSD-GQYSFCTQRNLMVTTRGGN--------------SNGAMCKFPFIYNGRNYTDCTADGRRDGMKWCGTTTNYDDEQRFGFC 463
[Close]
BLAST of Insulin like growth factor 2 receptor vs. Ensembl Sea Lamprey
Match: mmp2 (matrix metallopeptidase 2 [Source:ZFIN;Acc:ZDB-GENE-030131-9123])

HSP 1 Score: 51.2174 bits (121), Expect = 3.410e-7
Identity = 47/208 (22.60%), Postives = 77/208 (37.02%), Query Frame = 1 
Query:   70 LPSNSTIEMRVKTVNDKFCFFPFVYKNQTFDDCIPYAST-GSKFCPTTCNLESDNELSLCRWEKKNLLEPSCVNLTNSQPYREPSTVTNESCIFPFVYKNKCYNDCITL---DSYQLWCGATESSDLNPTQYAVCYYNRTQSDEKGCENLKNAKPSIQPETVSNGTCTFPFVYQENCYEDCV----PDEEPWCSFTKGYKIN-EFGYC 666
            L     I+ R        C FPF+++   +  C       G  +C TT + ++D +   C         PS   +T             + C FPFV+  + Y+ C      D Y+ WC  TE  D +   Y  C  +   +     E                  C FPFV+ ++ Y+ C      D + WC+ T  +  + ++G+C
Sbjct:  148 LGEGKVIKTRFGNAEGATCHFPFLFEGVEYTGCTAKGRKDGMLWCSTTADFDTDAKYGFC---------PSESLMTFG------GNGGGKPCKFPFVFLGETYDSCTATGRKDGYR-WCSTTEDYDRD-KLYGFCPSDAMATSGGNAEG---------------APCVFPFVFLDDSYDACTQNGRKDGKSWCATTSSFDDDKKWGFC 323
[Close]
BLAST of Insulin like growth factor 2 receptor vs. Ensembl Nematostella
Match: EDO32111 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SW03])

HSP 1 Score: 54.6842 bits (130), Expect = 2.030e-9
Identity = 38/112 (33.93%), Postives = 52/112 (46.43%), Query Frame = 1 
Query:  106 TVNDKFCFFPFVYKNQTFDDCIPYASTGSKFCPTTCNLESDNELSLCRWEKKNLLEPSCVNLTNSQPYREPSTVTNESCIFPFVYKNKCYNDCITLDSYQLWCGATESSDLN 441
            T N   CFFPF YK    + CI  A    ++C TT N ++D E   C         P C N+ +        T   + C FPF+YK+K Y  CI   + + WC  T + DL+
Sbjct:    7 TSNGACCFFPFTYKGVEQNRCIR-ADRNFRWCATTNNYDNDKEWGFC---------PHC-NVAHG------GTAGGDCCHFPFIYKSKVYQKCIRDSNGKPWCATTYNFDLD 101

HSP 2 Score: 49.2914 bits (116), Expect = 1.689e-7
Identity = 33/119 (27.73%), Postives = 48/119 (40.34%), Query Frame = 1 
Query:  319 STVTNESCIFPFVYKNKCYNDCITLDSYQLWCGATESSDLNPTQYAVCYYNRTQSDEKGCENLKNAKPSIQPETVSNGTCTFPFVYQENCYEDCVPDE--EPWCSFTKGYKINE-FGYC 666
             T     C FPF YK    N CI  D    WC  T + D N  ++  C +                       T     C FPF+Y+   Y+ C+ D   +PWC+ T  + +++ +GYC
Sbjct:    6 GTSNGACCFFPFTYKGVEQNRCIRADRNFRWCATTNNYD-NDKEWGFCPHCNVA----------------HGGTAGGDCCHFPFIYKSKVYQKCIRDSNGKPWCATTYNFDLDQKWGYC 107
[Close]
BLAST of Insulin like growth factor 2 receptor vs. Ensembl Nematostella
Match: EDO45372 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RT12])

HSP 1 Score: 47.3654 bits (111), Expect = 4.166e-7
Identity = 35/113 (30.97%), Postives = 46/113 (40.71%), Query Frame = 1 
Query:  340 CIFPFVYKNKCYNDCITLDSYQLWCGATESSDLNPTQYAVCYYNRTQSDEKGCENLKNAKPSIQPETVSNGTCTFPFVYQENCYEDCV---PDEEPWCSFTKGY-KINEFGYC 666
            C+FPFVY+ K YN C      + WC  T + D++   +  C   R   DE                      C FPF+Y+   Y  C        PWCS T  Y K  ++GYC
Sbjct:    1 CVFPFVYRGKRYNSCTRARHNRPWCAITPNYDVDKL-WGNCAGGR--GDE---------------------CCVFPFIYKGRRYNACTRRNSKRGPWCSLTNNYDKDRKWGYC 89
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BLAST of Insulin like growth factor 2 receptor vs. Ensembl Medaka
Match: mmp2 (matrix metallopeptidase 2 [Source:NCBI gene;Acc:100125419])

HSP 1 Score: 54.6842 bits (130), Expect = 1.780e-7
Identity = 54/211 (25.59%), Postives = 78/211 (36.97%), Query Frame = 1 
Query:   70 LPSNSTIEMRVKTVNDKFCFFPFVYKNQTFDDCIPYA-STGSKFCPTTCNLESDNELSLCRWEKKNLLEPSCVNLTNSQPYREPSTVTNESCIFPFVYKNKCYNDCIT--LDSYQLWCGATESSDLNPTQYAVCYYNRTQSDEKGCENLKNAKPSIQPETV-SNGT---CTFPFVYQENCYEDCV----PDEEPWCSFTKGYKIN-EFGYC 666
            L     ++ +    + +FC FPF++    +  C       G  +C TT N + D +   C  E   LL            +          C FPF ++ K Y+ C T   D    WC  TE  D + T Y  C                   P     TV  NG    C FPF +  + YE C      D + WC+ TK Y  + ++G+C
Sbjct:  215 LGEGQVVKAKFGNADGEFCKFPFLFMGTEYKSCTAQGRDDGFLWCSTTYNFDEDGKYGFCPHE---LL------------FTLGGNGDGAPCKFPFTFQGKQYDSCTTEGRDDGYRWCATTEDYDRD-TSYGFC-------------------PETAMSTVGGNGEGSPCVFPFTFLGDTYESCTTSGRSDGKMWCATTKSYDDDRKWGFC 390
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BLAST of Insulin like growth factor 2 receptor vs. Ensembl Medaka
Match: mmp2 (matrix metallopeptidase 2 [Source:NCBI gene;Acc:100125419])

HSP 1 Score: 54.6842 bits (130), Expect = 1.797e-7
Identity = 60/255 (23.53%), Postives = 89/255 (34.90%), Query Frame = 1 
Query:   70 LPSNSTIEMRVKTVNDKFCFFPFVYKNQTFDDCIPYA-STGSKFCPTTCNLESDNELSLCRWEKKNLLEPSCVNLTNSQPYREPSTVTNESCIFPFVYKNKCYNDCIT--LDSYQLWCGATESSDLNPTQYAVCYYNRTQSDEKGCENLKNAKPSIQPETV-SNGT---CTFPFVYQENCYEDCV----PDEEPWCSFTKGYKIN-------EFGYCKYLRSFQKWRSLWKSSGSIANNLKLHCSNRSRKHEISG 780
            L     ++ +    + +FC FPF++    +  C       G  +C TT N + D +   C  E   LL            +          C FPF ++ K Y+ C T   D    WC  TE  D + T Y  C                   P     TV  NG    C FPF +  + YE C      D + WC+ TK Y  +       + GY  +L   Q   +L     +   + +L   +     E+ G
Sbjct:  215 LGEGQVVKAKFGNADGEFCKFPFLFMGTEYKSCTAQGRDDGFLWCSTTYNFDEDGKYGFCPHE---LL------------FTLGGNGDGAPCKFPFTFQGKQYDSCTTEGRDDGYRWCATTEDYDRD-TSYGFC-------------------PETAMSTVGGNGEGSPCVFPFTFLGDTYESCTTSGRSDGKMWCATTKSYDDDRKWGFCPDQGYSLFLVHSQDPGALMAPVYTFTKDFRLPQDDIQGIQELYG 434
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BLAST of Insulin like growth factor 2 receptor vs. Planmine SMEST
Match: SMESG000023953.1 (SMESG000023953.1)

HSP 1 Score: 415.616 bits (1067), Expect = 0.000e+0
Identity = 200/205 (97.56%), Postives = 202/205 (98.54%), Query Frame = 1 
Query:   94 MRVKTVNDKFCFFPFVYKNQTFDDCIPYASTGSKFCPTTCNLESDNELSLCRWEKKNLLEPSCVNLTNSQPYREPSTVTNESCIFPFVYKNKCYNDCITLDSYQLWCGATESSDLNPTQYAVCYYNRTQSDEKGCENLKNAKPSIQPETVSNGTCTFPFVYQENCYEDCVPDEEPWCSFTKGYKINEFGYCKYLRSFQKWRSLWK 708
            MRVKTVNDKFCFFPFVYKNQTFDDCIPYASTGSKFCPTTCNLESDNELSLCRWEKKNLLEPSCVNLTNSQPYREPSTVTNESCIFPFVYKNKCYNDCITLDSYQLWCGATESSDLNPTQYAVCYYNRTQSDEKGCENLKNAKPSIQPETVSNGTCTFPFVYQENCYEDCVPDEEPWCSFTKGYKINEFGYCKYLRSFQK+ +  K
Sbjct:    1 MRVKTVNDKFCFFPFVYKNQTFDDCIPYASTGSKFCPTTCNLESDNELSLCRWEKKNLLEPSCVNLTNSQPYREPSTVTNESCIFPFVYKNKCYNDCITLDSYQLWCGATESSDLNPTQYAVCYYNRTQSDEKGCENLKNAKPSIQPETVSNGTCTFPFVYQENCYEDCVPDEEPWCSFTKGYKINEFGYCKYLRSFQKFETGLK 205

HSP 2 Score: 331.257 bits (848), Expect = 0.000e+0
Identity = 161/164 (98.17%), Postives = 163/164 (99.39%), Query Frame = 2 
Query:  692 GDLCGSQVVASQITSNSIVQIAHGNTKYLVNKWEVLPQPNNSIIIRSPKMCPITLQNAWKYSLNNQIILGELKTYKLNTRFILNPHLTVPNIYFLTTIIGDNIESNSIVGFQMSSKNKLGIVPLERYPLPAYWKFELVKELDANFNEDPCGIQTSFETSTEQSQ 1183
            GDLCGSQVVASQITSNSIVQIAHGNTKYLVNKWEVLPQPNNSIIIRSPKMCPITLQNAWKYSLNNQIILGELKTYKLNTRFILNPHLTVPNIYFLTTIIG+NIESNSIVGFQMSSKNKL IVPLERYPLPAYWKFELVKELDANFNEDPCGIQTSFETSTEQS+
Sbjct:  218 GDLCGSQVVASQITSNSIVQIAHGNTKYLVNKWEVLPQPNNSIIIRSPKMCPITLQNAWKYSLNNQIILGELKTYKLNTRFILNPHLTVPNIYFLTTIIGNNIESNSIVGFQMSSKNKLSIVPLERYPLPAYWKFELVKELDANFNEDPCGIQTSFETSTEQSR 381

HSP 3 Score: 66.6254 bits (161), Expect = 1.296e-11
Identity = 45/150 (30.00%), Postives = 69/150 (46.00%), Query Frame = 1 
Query:  322 TVTNESCIFPFVYKNKCYNDCITLDSYQLWCGATESSDLNPTQYAVCYYNRTQSDEKGCENLKNAKPSIQPETVSNGTCTFPFVYQENCYEDCVPDEEPWCSFTKGYKINEFGYCKYLRSFQKWRSLWKSSGSIANNLKLHCSNRSRKHE 771
            TV ++ C FPFVYKN+ ++DCI   S       T  +  +  + ++C + +    E  C NL N++P  +P TV+N +C FPFVY+  CY DC+                       L S+Q W    +SS        +   NR++  E
Sbjct:    5 TVNDKFCFFPFVYKNQTFDDCIPYASTGSKFCPTTCNLESDNELSLCRWEKKNLLEPSCVNLTNSQPYREPSTVTNESCIFPFVYKNKCYNDCIT----------------------LDSYQLWCGATESSDLNPTQYAVCYYNRTQSDE 132
The following BLAST results are available for this feature:
BLAST of Insulin like growth factor 2 receptor vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
MMP22.323e-824.06matrix metallopeptidase 2 [Source:HGNC Symbol;Acc:... [more]
MMP22.516e-824.06matrix metallopeptidase 2 [Source:HGNC Symbol;Acc:... [more]
MMP22.516e-824.06matrix metallopeptidase 2 [Source:HGNC Symbol;Acc:... [more]
MMP23.368e-824.06matrix metallopeptidase 2 [Source:HGNC Symbol;Acc:... [more]
ELSPBP19.383e-825.63epididymal sperm binding protein 1 [Source:HGNC Sy... [more]
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BLAST of Insulin like growth factor 2 receptor vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Insulin like growth factor 2 receptor vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Insulin like growth factor 2 receptor vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
mmp91.612e-724.52matrix metallopeptidase 9 [Source:ZFIN;Acc:ZDB-GEN... [more]
mmp22.271e-623.08matrix metallopeptidase 2 [Source:ZFIN;Acc:ZDB-GEN... [more]
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BLAST of Insulin like growth factor 2 receptor vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
mmp9.14.834e-825.48matrix metallopeptidase 9 gene 2 [Source:NCBI gene... [more]
mmp9.15.583e-825.00matrix metallopeptidase 9 gene 2 [Source:NCBI gene... [more]
mmp9.16.461e-825.48matrix metallopeptidase 9 gene 2 [Source:NCBI gene... [more]
mmp9.11.095e-722.22matrix metallopeptidase 9 gene 2 [Source:NCBI gene... [more]
mmp9.12.319e-723.56matrix metallopeptidase 9 gene 2 [Source:NCBI gene... [more]
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BLAST of Insulin like growth factor 2 receptor vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 2
Match NameE-valueIdentityDescription
Mmp21.156e-823.51matrix metallopeptidase 2 [Source:MGI Symbol;Acc:M... [more]
Mmp92.421e-623.62matrix metallopeptidase 9 [Source:MGI Symbol;Acc:M... [more]
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BLAST of Insulin like growth factor 2 receptor vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P33434|MMP2_MOUSE8.084e-823.5172 kDa type IV collagenase OS=Mus musculus OX=1009... [more]
sp|P33436|MMP2_RAT1.125e-725.4772 kDa type IV collagenase OS=Rattus norvegicus OX... [more]
sp|P08253|MMP2_HUMAN1.617e-724.0672 kDa type IV collagenase OS=Homo sapiens OX=9606... [more]
sp|P50757|MMP2_RABIT1.065e-622.3972 kDa type IV collagenase OS=Oryctolagus cuniculu... [more]
sp|Q96BH3|ESPB1_HUMAN1.532e-624.72Epididymal sperm-binding protein 1 OS=Homo sapiens... [more]
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BLAST of Insulin like growth factor 2 receptor vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1I8GD551.113e-2129.57Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A267E5304.697e-1930.86Uncharacterized protein (Fragment) OS=Macrostomum ... [more]
A0A267GYT26.826e-1930.45Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A267FHF85.021e-1829.06Uncharacterized protein (Fragment) OS=Macrostomum ... [more]
A0A1I8FYL05.034e-1828.13Uncharacterized protein OS=Macrostomum lignano OX=... [more]
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BLAST of Insulin like growth factor 2 receptor vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
mmp91.226e-723.56matrix metallopeptidase 9 [Source:ZFIN;Acc:ZDB-GEN... [more]
mmp91.345e-723.56matrix metallopeptidase 9 [Source:ZFIN;Acc:ZDB-GEN... [more]
mmp91.345e-723.56matrix metallopeptidase 9 [Source:ZFIN;Acc:ZDB-GEN... [more]
ENSAMXT00000056262.11.693e-632.14pep primary_assembly:Astyanax_mexicanus-2.0:12:276... [more]
ENSAMXT00000035233.12.428e-632.14pep primary_assembly:Astyanax_mexicanus-2.0:12:276... [more]
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BLAST of Insulin like growth factor 2 receptor vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
mmp23.410e-722.60matrix metallopeptidase 2 [Source:ZFIN;Acc:ZDB-GEN... [more]
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BLAST of Insulin like growth factor 2 receptor vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Insulin like growth factor 2 receptor vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO321112.030e-933.93Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO453724.166e-730.97Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Insulin like growth factor 2 receptor vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 2
Match NameE-valueIdentityDescription
mmp21.780e-725.59matrix metallopeptidase 2 [Source:NCBI gene;Acc:10... [more]
mmp21.797e-723.53matrix metallopeptidase 2 [Source:NCBI gene;Acc:10... [more]
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BLAST of Insulin like growth factor 2 receptor vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000023953.11.296e-1197.56SMESG000023953.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30018829 ID=SMED30018829|Name=Insulin like growth factor 2 receptor|organism=Schmidtea mediterranea sexual|type=transcript|length=1479bp
TTTTGGTTTTTAACTTTTGAAAATTCAATCTATCATTCTCATGGAGGTAA
TTTTACAACAAAGTCTTGTTTGCCTTCAAATTCCACTATTGAAATGCGAG
TTAAAACAGTTAATGACAAATTCTGTTTTTTTCCATTTGTCTACAAAAAC
CAAACATTTGATGATTGCATACCTTATGCATCGACGGGTAGTAAATTCTG
TCCAACCACTTGCAATTTAGAATCGGATAATGAGTTGTCCTTATGTCGAT
GGGAGAAAAAAAATCTTTTGGAACCATCGTGCGTAAATTTGACGAATTCT
CAACCATATAGAGAACCTTCAACTGTGACAAATGAATCTTGTATTTTCCC
ATTCGTTTACAAAAACAAATGTTATAATGATTGCATAACTTTGGATTCCT
ATCAGCTATGGTGTGGAGCAACGGAATCGTCGGACCTGAATCCGACCCAA
TACGCTGTTTGTTATTATAATCGAACTCAAAGCGATGAAAAAGGCTGTGA
AAATCTTAAAAACGCTAAACCATCAATTCAACCTGAAACTGTCAGTAATG
GAACTTGTACATTTCCATTCGTTTACCAAGAAAATTGTTATGAAGACTGT
GTACCAGATGAAGAACCTTGGTGCTCGTTTACTAAAGGTTACAAGATAAA
TGAATTCGGATACTGCAAGTACCTGAGAAGTTTTCAAAAATGGAGATCTC
TGTGGAAGTCAAGTGGTAGCATCGCAAATAACCTCAAACTCCATTGTTCA
AATCGCTCACGGAAACACGAAATATCTGGTTAATAAATGGGAAGTTTTAC
CTCAACCTAACAATTCAATTATAATCAGATCGCCAAAAATGTGCCCAATA
ACTTTACAAAATGCATGGAAATATAGTTTGAATAATCAAATCATTCTTGG
GGAATTAAAGACATACAAATTAAATACCAGATTTATTTTGAATCCCCACC
TTACGGTGCCGAATATTTATTTCTTAACAACAATAATTGGAGATAACATT
GAATCTAACTCCATTGTTGGTTTTCAGATGTCATCCAAAAATAAGTTGGG
CATTGTACCATTGGAACGCTACCCCTTGCCAGCTTATTGGAAATTTGAAC
TGGTAAAGGAACTTGATGCTAATTTTAATGAAGATCCCTGTGGAATTCAA
ACAAGTTTCGAAACGTCAACTGAACAGTCGCAAAAAGAATTTATTACTAC
TCCAACCAATAACAAATATGAATCAGAAATGAATAACATAAAGATCACAG
TCATCGTGACGATTGTTATAAGTTTGATAGTTCTTATCATCGCGTTGGCG
ATTATCATTACCATGTGTCGGAATCATTGACGAACTTTGTATTCGCTCTT
GAAACTATCTTTCTATAGATAATTGAAGCCTTATCCAAATATGTTTTCAA
CGAAAATACTAGACAATTCGTCGCTTTTTGTTTAAATAAAGACAATCGGA
CGACATTTATTTTAGAATAGAATTTATAC
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protein sequence of SMED30018829-orf-1

>SMED30018829-orf-1 ID=SMED30018829-orf-1|Name=SMED30018829-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=261bp
FWFLTFENSIYHSHGGNFTTKSCLPSNSTIEMRVKTVNDKFCFFPFVYKN
QTFDDCIPYASTGSKFCPTTCNLESDNELSLCRWEKKNLLEPSCVNLTNS
QPYREPSTVTNESCIFPFVYKNKCYNDCITLDSYQLWCGATESSDLNPTQ
YAVCYYNRTQSDEKGCENLKNAKPSIQPETVSNGTCTFPFVYQENCYEDC
VPDEEPWCSFTKGYKINEFGYCKYLRSFQKWRSLWKSSGSIANNLKLHCS
NRSRKHEISG*
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protein sequence of SMED30018829-orf-2

>SMED30018829-orf-2 ID=SMED30018829-orf-2|Name=SMED30018829-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=164bp
MCPITLQNAWKYSLNNQIILGELKTYKLNTRFILNPHLTVPNIYFLTTII
GDNIESNSIVGFQMSSKNKLGIVPLERYPLPAYWKFELVKELDANFNEDP
CGIQTSFETSTEQSQKEFITTPTNNKYESEMNNIKITVIVTIVISLIVLI
IALAIIITMCRNH*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0005520insulin-like growth factor binding
GO:0005537mannose binding
GO:0038023signaling receptor activity
GO:0042802identical protein binding
GO:0051219phosphoprotein binding
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
GO:0005641nuclear envelope lumen
GO:0005768endosome
GO:0005769early endosome
GO:0005770late endosome
GO:0005794Golgi apparatus
GO:0005802trans-Golgi network
GO:0009986cell surface
GO:0030139endocytic vesicle
GO:0030140trans-Golgi network transport vesicle
GO:0016020membrane
GO:0016021integral component of membrane
Vocabulary: biological process
TermDefinition
GO:0007041lysosomal transport
GO:0044794positive regulation by host of viral process
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000420parapharyngeal region
Vocabulary: INTERPRO
TermDefinition
IPR036943FN_type2_sf
IPR000562FN_type2_dom
IPR013806Kringle-like
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000562Fibronectin type II domainSMARTSM00059FN2_2coord: 97..144
e-value: 2.1E-4
score: 17.8
coord: 25..72
e-value: 8.0E-4
score: 13.2
coord: 169..212
e-value: 1.1E-4
score: 20.3
IPR000562Fibronectin type II domainPFAMPF00040fn2coord: 32..72
e-value: 1.3E-7
score: 31.7
coord: 104..136
e-value: 1.5E-8
score: 34.8
coord: 176..212
e-value: 1.8E-6
score: 28.1
IPR000562Fibronectin type II domainPROSITEPS51092FN2_2coord: 99..146
score: 13.02
IPR000562Fibronectin type II domainPROSITEPS51092FN2_2coord: 171..214
score: 12.987
IPR000562Fibronectin type II domainPROSITEPS51092FN2_2coord: 27..74
score: 11.946
IPR036943Fibronectin type II domain superfamilyGENE3DG3DSA:2.10.10.10coord: 96..145
e-value: 4.2E-10
score: 41.2
IPR036943Fibronectin type II domain superfamilyGENE3DG3DSA:2.10.10.10coord: 162..217
e-value: 1.9E-8
score: 36.0
coord: 14..77
e-value: 1.2E-8
score: 36.7
NoneNo IPR availablePANTHERPTHR22918SEMINAL PLASMA PROTEINcoord: 98..132
NoneNo IPR availablePANTHERPTHR22918:SF12BINDER OF SPERM PROTEIN HOMOLOG 1coord: 98..132
IPR013806Kringle-like foldSUPERFAMILYSSF57440Kringle-likecoord: 170..213
IPR013806Kringle-like foldSUPERFAMILYSSF57440Kringle-likecoord: 98..144
IPR013806Kringle-like foldSUPERFAMILYSSF57440Kringle-likecoord: 23..73