rhomboid-like protein

Overview
Namerhomboid-like protein (AHY82405.1)
Smed IDSMED30018825
Length (bp)1494
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of rhomboid-like protein (SMED30018825) t-SNE clustered cells

Violin plots show distribution of expression levels for rhomboid-like protein (SMED30018825) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of rhomboid-like protein (SMED30018825) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for rhomboid-like protein (SMED30018825) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30018825

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 5

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
nervous systemSMED30018825h1SMcG0017380 dd_Smed_v4_13835_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30018825h1SMcG0017380 dd_Smed_v4_13835_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30018825h1SMcG0017380 dd_Smed_v4_13835_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30018825h1SMcG0017380 dd_Smed_v4_13835_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
pigment cellSMED30018825h1SMcG0017380 SMED30018825smed_20140614PMID:22884275
Lapan et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of rhomboid-like protein vs. Ensembl Human
Match: RHBDL3 (rhomboid like 3 [Source:HGNC Symbol;Acc:HGNC:16502])

HSP 1 Score: 139.043 bits (349), Expect = 8.371e-36
Identity = 113/378 (29.89%), Postives = 196/378 (51.85%), Query Frame = 2 
Query:  164 DQTFKTMFDEYDSMG---MPTQCLLKLLRRDSLGIPRQRLNRFIMRLDANKDGRVTYEEFRLFMLNIEPRDISFAKKILISLALKSCPDLINSYLPG-SCEENLMREEERHKLKNELAES-YLDAYSCYPPPVFIPIILVAQMASFVFYGLQLIHEDDPKNMLSWTTGIPRKSPLIFDVHKRIEIWRFFSYMLIHQGYLHIIFNCXXXXXXXXXXXXVHKFWRVGPVYXXXXXXXXXXXXIIDKNSKLVGSSGGSYALIGAHFAIVIMNWDELQRDWLKIKVNFLNFVASGVVRLLFLITFLTADLGTSLYRRL---GLDITEQTSTASHIGGFVAGLLFGIPCLRNIRKKIWEVKLFWVSLSIYTGLLGFAILWNIF 1273
            +  +K +FD++D      + T     LL   S  +   +    +   D++ DG++ Y++F   M N   R  SF + IL      S   L+     G S  + L+R      L  E+    Y D+Y+C PPP F+  + + ++A F++ G+ L      + +L  T     K+ L++    R ++WR+ +Y+ +H G  H+  N ++QLL+G+PLE+VH   R+G VY++GV+AGSLA S+ D  + +VGSSGG YAL+ AH A ++MNW  +       K  F       ++R+   +  ++ + G +++ R            S  +H+GG   G+  G+  LRN  +++ +  L+W+ +++YT  + FA+ WNIF
Sbjct:   36 EDHWKVLFDQFDPGNTGYISTGKFRSLLESHSSKLDPHKREVLLALADSHADGQIGYQDFVSLMSN--KRSNSFRQAILQGNRRLSSKALLEE--KGLSLSQRLIRHVAYETLPREIDRKWYYDSYTCCPPPWFMITVTLLEVAFFLYNGVSL-----GQFVLQVTHPRYLKNSLVYHPQLRAQVWRYLTYIFMHAGIEHLGLNVVLQLLVGVPLEMVHGATRIGLVYVAGVVAGSLAVSVADMTAPVVGSSGGVYALVSAHLANIVMNWSGM-------KCQF------KLLRMAVALICMSMEFGRAVWLRFHPSAYPPCPHPSFVAHLGGVAVGITLGVVVLRNYEQRLQDQSLWWIFVAMYTVFVLFAVFWNIF 391
[Close]
BLAST of rhomboid-like protein vs. Ensembl Human
Match: RHBDL3 (rhomboid like 3 [Source:HGNC Symbol;Acc:HGNC:16502])

HSP 1 Score: 135.576 bits (340), Expect = 1.087e-34
Identity = 110/372 (29.57%), Postives = 191/372 (51.34%), Query Frame = 2 
Query:  185 FDEYDSMGMPTQCLLKLLRRDSLGIPRQRLNRFIMRLDANKDGRVTYEEFRLFMLNIEPRDISFAKKILISLALKSCPDLINSYLPG-SCEENLMREEERHKLKNELAES-YLDAYSCYPPPVFIPIILVAQMASFVFYGLQL----IHEDDPKNMLSWTTGIPRKSPLIFDVHKRIEIWRFFSYMLIHQGYLHIIFNCXXXXXXXXXXXXVHKFWRVGPVYXXXXXXXXXXXXIIDKNSKLVGSSGGSYALIGAHFAIVIMNWDELQRDWLKIKVNFLNFVASGVVRLLFLITFLTADLGTSLYRRL---GLDITEQTSTASHIGGFVAGLLFGIPCLRNIRKKIWEVKLFWVSLSIYTGLLGFAILWNIF 1273
            FD  ++  + T     LL   S  +   +    +   D++ DG++ Y++F   M N   R  SF + IL      S   L+     G S  + L+R      L  E+    Y D+Y+C PPP F+  + + ++A F++ G+ L    +    P+ +         K+ L++    R ++WR+ +Y+ +H G  H+  N ++QLL+G+PLE+VH   R+G VY++GV+AGSLA S+ D  + +VGSSGG YAL+ AH A ++MNW  +       K  F       ++R+   +  ++ + G +++ R            S  +H+GG   G+  G+  LRN  +++ +  L+W+ +++YT  + FA+ WNIF
Sbjct:   38 FDPGNTGYISTGKFRSLLESHSSKLDPHKREVLLALADSHADGQIGYQDFVSLMSN--KRSNSFRQAILQGNRRLSSKALLEE--KGLSLSQRLIRHVAYETLPREIDRKWYYDSYTCCPPPWFMITVTLLEVAFFLYNGVSLGQFVLQVTHPRYL---------KNSLVYHPQLRAQVWRYLTYIFMHAGIEHLGLNVVLQLLVGVPLEMVHGATRIGLVYVAGVVAGSLAVSVADMTAPVVGSSGGVYALVSAHLANIVMNWSGM-------KCQF------KLLRMAVALICMSMEFGRAVWLRFHPSAYPPCPHPSFVAHLGGVAVGITLGVVVLRNYEQRLQDQSLWWIFVAMYTVFVLFAVFWNIF 383
[Close]
BLAST of rhomboid-like protein vs. Ensembl Human
Match: RHBDL2 (rhomboid like 2 [Source:HGNC Symbol;Acc:HGNC:16083])

HSP 1 Score: 133.265 bits (334), Expect = 1.310e-34
Identity = 107/256 (41.80%), Postives = 153/256 (59.77%), Query Frame = 2 
Query:  509 SYLDAYSCYPPPVFIPIILVAQMASFVFYGLQLIHEDDPKNMLSWTTGIPRKSPLIFDVHKRIEIWRFFSYMLIHQGYLHIIFNCXXXXXXXXXXXXVHKFWRVGPVYXXXXXXXXXXXXIIDKNSKLVGSSGGSYALIGAHFAIVIMNWDELQRDWLKIKVNFLNFVASGVVRLLFLITFLTADLGTSLYRRLGL-DITEQTSTASHIGGFVAGLLFGIPCLRNIRKKIWEVKLFWVSLSIYTGLLGFAILWNIF 1273
            +YL+  +C+PPPVFI  I +A++A F++Y +        K  ++  TGI  +SP I+   KR E WRF SYML+H G  HI+ N  +QL+LGIPLE+VHK  RVG VYL+GV+AGSLASSI D    LVG+SGG YAL+G +F  V++N+ E+               A G+ RLL +I  +  D+G +LYRR  + +     S A+HI G  AG+  G        K + +   FW++++ Y   + FA+ +NIF
Sbjct:   61 TYLERANCFPPPVFIISISLAELAVFIYYAVW----KPQKQWITLDTGI-LESPFIYSPEKREEAWRFISYMLVHAGVQHILGNLCMQLVLGIPLEMVHKGLRVGLVYLAGVIAGSLASSIFDPLRYLVGASGGVYALMGGYFMNVLVNFQEM-------------IPAFGIFRLLIIILIIVLDMGFALYRRFFVPEDGSPVSFAAHIAGGFAGMSIGYTVFSCFDKALLKDPRFWIAIAAYLACVLFAVFFNIF 298
[Close]
BLAST of rhomboid-like protein vs. Ensembl Human
Match: RHBDL2 (rhomboid like 2 [Source:HGNC Symbol;Acc:HGNC:16083])

HSP 1 Score: 133.265 bits (334), Expect = 1.310e-34
Identity = 107/256 (41.80%), Postives = 153/256 (59.77%), Query Frame = 2 
Query:  509 SYLDAYSCYPPPVFIPIILVAQMASFVFYGLQLIHEDDPKNMLSWTTGIPRKSPLIFDVHKRIEIWRFFSYMLIHQGYLHIIFNCXXXXXXXXXXXXVHKFWRVGPVYXXXXXXXXXXXXIIDKNSKLVGSSGGSYALIGAHFAIVIMNWDELQRDWLKIKVNFLNFVASGVVRLLFLITFLTADLGTSLYRRLGL-DITEQTSTASHIGGFVAGLLFGIPCLRNIRKKIWEVKLFWVSLSIYTGLLGFAILWNIF 1273
            +YL+  +C+PPPVFI  I +A++A F++Y +        K  ++  TGI  +SP I+   KR E WRF SYML+H G  HI+ N  +QL+LGIPLE+VHK  RVG VYL+GV+AGSLASSI D    LVG+SGG YAL+G +F  V++N+ E+               A G+ RLL +I  +  D+G +LYRR  + +     S A+HI G  AG+  G        K + +   FW++++ Y   + FA+ +NIF
Sbjct:   61 TYLERANCFPPPVFIISISLAELAVFIYYAVW----KPQKQWITLDTGI-LESPFIYSPEKREEAWRFISYMLVHAGVQHILGNLCMQLVLGIPLEMVHKGLRVGLVYLAGVIAGSLASSIFDPLRYLVGASGGVYALMGGYFMNVLVNFQEM-------------IPAFGIFRLLIIILIIVLDMGFALYRRFFVPEDGSPVSFAAHIAGGFAGMSIGYTVFSCFDKALLKDPRFWIAIAAYLACVLFAVFFNIF 298
[Close]
BLAST of rhomboid-like protein vs. Ensembl Human
Match: RHBDL3 (rhomboid like 3 [Source:HGNC Symbol;Acc:HGNC:16502])

HSP 1 Score: 124.79 bits (312), Expect = 1.546e-31
Identity = 89/284 (31.34%), Postives = 156/284 (54.93%), Query Frame = 2 
Query:  446 SCEENLMREEERHKLKNELAES-YLDAYSCYPPPVFIPIILVAQMASFVFYGLQL----IHEDDPKNMLSWTTGIPRKSPLIFDVHKRIEIWRFFSYMLIHQGYLHIIFNCXXXXXXXXXXXXVHKFWRVGPVYXXXXXXXXXXXXIIDKNSKLVGSSGGSYALIGAHFAIVIMNWDELQRDWLKIKVNFLNFVASGVVRLLFLITFLTADLGTSLYRRL---GLDITEQTSTASHIGGFVAGLLFGIPCLRNIRKKIWEVKLFWVSLSIYTGLLGFAILWNIF 1273
            S  + L+R      L  E+    Y D+Y+C PPP F+  + + ++A F++ G+ L    +    P+ +         K+ L++    R ++WR+ +Y+ +H G  H+  N ++QLL+G+PLE+VH   R+G VY++GV+AGSLA S+ D  + +VGSSGG YAL+ AH A ++MNW  +       K  F       ++R+   +  ++ + G +++ R            S  +H+GG   G+  G+  LRN  +++ +  L+W+ +++YT  + FA+ WNIF
Sbjct:   32 SLSQRLIRHVAYETLPREIDRKWYYDSYTCCPPPWFMITVTLLEVAFFLYNGVSLGQFVLQVTHPRYL---------KNSLVYHPQLRAQVWRYLTYIFMHAGIEHLGLNVVLQLLVGVPLEMVHGATRIGLVYVAGVVAGSLAVSVADMTAPVVGSSGGVYALVSAHLANIVMNWSGM-------KCQF------KLLRMAVALICMSMEFGRAVWLRFHPSAYPPCPHPSFVAHLGGVAVGITLGVVVLRNYEQRLQDQSLWWIFVAMYTVFVLFAVFWNIF 293
[Close]
BLAST of rhomboid-like protein vs. Ensembl Celegans
Match: rom-1 (Rhomboid-related protein 1 [Source:UniProtKB/Swiss-Prot;Acc:Q19821])

HSP 1 Score: 134.806 bits (338), Expect = 4.540e-35
Identity = 101/267 (37.83%), Postives = 142/267 (53.18%), Query Frame = 2 
Query:  506 ESYLDAYSCYPPPVFIPIILVAQMASFVFY----GLQLIHEDDPKNMLSWTTGIPRKSPLIFDVHKRIEIWRFFSYMLIHQGYLHIIFNCXXXXXXXXXXXXVHKFWRVGPVYXXXXXXXXXXXXIIDKNSKLVGSSGGSYALIGAHFAIVIMNWDELQRDWLKIKVNFLNFVASGVVRLLFLITFLTADLGTSLYRRLGLDITEQTSTASHIGGFVAGLLFGIPCLRNIRKKIWEVKLFWVSLSIYTGLLGFAILWNIFYPGYNES 1294
             SY+D+YS  PPP+F+ +I + Q+  F FY    G + I  D     +      P     IF    R E WRF SYM +H G  H++ N +IQLL+GIPLE+ HK WR+GP+YL  V +GSL    ID NS LVG+S G YALI AH A VI+NW E+   W               +R+L L  F+  D G +++RR   +  +  S  +HI G V GL FG   L N+ +   E  + +V L +Y+      I++ I    Y+++
Sbjct:   99 HSYIDSYSWCPPPIFMLLITIIQVGIFFFYWESDGGRSIWTDCAGCFVHHNHTAP--GIFIFAPKLRGEAWRFTSYMFLHAGLNHLLGNVIIQLLVGIPLEVAHKIWRIGPIYLLAVTSGSLLQYAIDPNSLLVGASAGVYALIFAHVANVILNWHEMPLRW---------------IRVLVLFVFIFLDFGGAIHRRFYTNDCDSVSHLAHIAGAVTGLFFGYVVLYNVVEHRIEKIIRYVCLFLYSAFFATTIIFVIVRQPYSKN 348
[Close]
BLAST of rhomboid-like protein vs. Ensembl Celegans
Match: rom-2 (Rhomboid-related protein 2 [Source:UniProtKB/Swiss-Prot;Acc:P34356])

HSP 1 Score: 110.538 bits (275), Expect = 4.366e-26
Identity = 94/272 (34.56%), Postives = 137/272 (50.37%), Query Frame = 2 
Query:  434 YLPGSCE-----ENLMREEERHKLKNELAE--SYLDAYSCYPPPVFIPIILVAQMASFVFYGLQLIHEDDPKNMLSWTTG-IPRKSPLIFDVHKRIEIWRFFSYMLIHQGYLHIIFNCXXXXXXXXXXXXVHKFWRVGPVYXXXXXXXXXXXXIIDKNSKLVGSSGGSYALIGAHFAIVIMNWDELQRDWLKIKVNFLNFVASGVVRLLFLITFLTADLGTSLYRRLGLDITEQTSTASHIGGFVAGLLFGIPCLRNIRKKIWEVKLFWVSL 1225
            YL   C+     E L R       KN+     S L  Y C PPP+F+  + + Q+A +++Y +     D  + +  W +G IP  SPLI   +   E+WR F+Y LI+ G  HIIFN LIQL +G+PLELVH+ WR+  +Y  GVL GS+ S  +D    L G + GS++LI +H   +  N+ E++               +   RL  LI F   D   ++Y+R      ++ S   H+GG VAG+LF     R  +   +    FWVSL
Sbjct:   79 YLMSKCKGYRLREYLFRAALTVTPKNQRIHVFSELQRYKCVPPPIFLIFLSIVQLAFYLYYVV-----DSSEGV--WLSGPIPTMSPLIVSQYHLPELWRLFTYCLINVGIFHIIFNILIQLAIGVPLELVHR-WRIYILYFMGVLFGSILSLALDPTVFLCGGAAGSFSLIASHITTIATNFKEME---------------NATCRLPILIVFAALDYVLAVYQRFFAPRIDKVSMYGHLGGLVAGILFTFILFRGSKPSRFYTVSFWVSL 327
[Close]
BLAST of rhomboid-like protein vs. Ensembl Fly
Match: rho-4 (gene:FBgn0030318 transcript:FBtr0073519)

HSP 1 Score: 151.754 bits (382), Expect = 1.013e-40
Identity = 133/397 (33.50%), Postives = 204/397 (51.39%), Query Frame = 2 
Query:  116 NMTASVLSEDIYTNWLDQTFKTMFDEYDSM--GMPTQCLLKLLRRDSL--GIPRQRLNRFIMRLDANKDGRVTYEEFRLFMLNIEPRDISFAKKILISLALKSCPDLINSYLPGSCEENLMREEERHKLKNELAESYLDAYSCYPPPVFIPIILVAQMASFVFYGLQLIH-EDDP--KNMLSWTTGIPRKSPLIFDVHKRIEIWRFFSYMLIHQGYLHIIFNCXXXXXXXXXXXXVHKFWRVGPVYXXXXXXXXXXXXIIDKNSKLVGSSGGSYALIGAHFAIVIMNWDELQRDWLKIKVNFLNFVASGVVRLLFLITFLTADLGTSLYRRLGLDITEQTSTASHIGGFVAGLLFGIPCLRNIRKKIWEVKLFWVSLSIYTGLLGFAILWNIFYPGY 1285
            N T S   ED       +    +FD++DS   G+     LK L  D     IP    ++ + R D + DG + +EEF    L          K ++ ++  + C  ++    P   E             +E   +Y    S  PPP+ + +  + ++  F+   + +IH +DDP  ++ +  +T  P  +  I++ +KR E WRF SYM +H G +H++ N +IQ+ LGI LELVH +WRVG VYL+GVLAGS+ +S+      L G+SGG YALI AH A +IMN+ E++                 +V+LL  + F   DLGTS+YR L  D  +Q    +H+ G VAGLL GI  LRN+  + WE  L+WV++ +Y  L+   I+ ++F P Y
Sbjct:   61 NQTNSQEPED------RRKMHEIFDKHDSDRDGLINTHELKELISDGYCRDIPAYIADQILKRSDQDNDGHLDFEEFYAMSLR--------HKWMVRNMLTRYCRYVVPP--PKPLE------------GDEPDGAYEKQMSICPPPLTMVLFSIIEIIMFL---VDVIHFQDDPNYQDRIGESTSGPAATLFIYNPYKRYEGWRFVSYMFVHVGIMHLMMNLIIQIFLGIALELVHHWWRVGLVYLAGVLAGSMGTSLTSPRIFLAGASGGVYALITAHIATIIMNYSEME---------------YAIVQLLAFLVFCFTDLGTSVYRHL-TDQHDQIGYVAHLSGAVAGLLVGIGVLRNLEVRRWERILWWVAVIVYFALMTTGIIIHVFVPDY 410
[Close]
BLAST of rhomboid-like protein vs. Ensembl Fly
Match: rho-4 (gene:FBgn0030318 transcript:FBtr0073518)

HSP 1 Score: 151.754 bits (382), Expect = 1.013e-40
Identity = 133/397 (33.50%), Postives = 204/397 (51.39%), Query Frame = 2 
Query:  116 NMTASVLSEDIYTNWLDQTFKTMFDEYDSM--GMPTQCLLKLLRRDSL--GIPRQRLNRFIMRLDANKDGRVTYEEFRLFMLNIEPRDISFAKKILISLALKSCPDLINSYLPGSCEENLMREEERHKLKNELAESYLDAYSCYPPPVFIPIILVAQMASFVFYGLQLIH-EDDP--KNMLSWTTGIPRKSPLIFDVHKRIEIWRFFSYMLIHQGYLHIIFNCXXXXXXXXXXXXVHKFWRVGPVYXXXXXXXXXXXXIIDKNSKLVGSSGGSYALIGAHFAIVIMNWDELQRDWLKIKVNFLNFVASGVVRLLFLITFLTADLGTSLYRRLGLDITEQTSTASHIGGFVAGLLFGIPCLRNIRKKIWEVKLFWVSLSIYTGLLGFAILWNIFYPGY 1285
            N T S   ED       +    +FD++DS   G+     LK L  D     IP    ++ + R D + DG + +EEF    L          K ++ ++  + C  ++    P   E             +E   +Y    S  PPP+ + +  + ++  F+   + +IH +DDP  ++ +  +T  P  +  I++ +KR E WRF SYM +H G +H++ N +IQ+ LGI LELVH +WRVG VYL+GVLAGS+ +S+      L G+SGG YALI AH A +IMN+ E++                 +V+LL  + F   DLGTS+YR L  D  +Q    +H+ G VAGLL GI  LRN+  + WE  L+WV++ +Y  L+   I+ ++F P Y
Sbjct:   61 NQTNSQEPED------RRKMHEIFDKHDSDRDGLINTHELKELISDGYCRDIPAYIADQILKRSDQDNDGHLDFEEFYAMSLR--------HKWMVRNMLTRYCRYVVPP--PKPLE------------GDEPDGAYEKQMSICPPPLTMVLFSIIEIIMFL---VDVIHFQDDPNYQDRIGESTSGPAATLFIYNPYKRYEGWRFVSYMFVHVGIMHLMMNLIIQIFLGIALELVHHWWRVGLVYLAGVLAGSMGTSLTSPRIFLAGASGGVYALITAHIATIIMNYSEME---------------YAIVQLLAFLVFCFTDLGTSVYRHL-TDQHDQIGYVAHLSGAVAGLLVGIGVLRNLEVRRWERILWWVAVIVYFALMTTGIIIHVFVPDY 410
[Close]
BLAST of rhomboid-like protein vs. Ensembl Fly
Match: stet (gene:FBgn0020248 transcript:FBtr0072712)

HSP 1 Score: 142.51 bits (358), Expect = 8.943e-37
Identity = 126/405 (31.11%), Postives = 198/405 (48.89%), Query Frame = 2 
Query:  161 LDQTFKTMFDEYDSMG---MPTQCLLKLLRRDSL--GIPRQRLNRFIMRLDANK----DGRVTYEEF---------RLFMLNIEPRDISFAKKILISLALKSCPDLINSYLPGSCEENLMREEERHKLKNELAESYLDAYSCYPPPVFIPIILVAQMASFVFYGLQLIHEDDPKNMLSWTTGIPRKSPLIFDVHKRIEIWRFFSYMLIHQGYLHIIFNCXXXXXXXXXXXXVHKFWRVGPVYXXXXXXXXXXXXIIDKNSKLVGSSGGSYALIGAHFAIVIMNWDELQRDWLKIKVNFLNFVASGVVRLLFLITFLTADLGTSLYRRLGLD-----------ITEQTSTA------SHIGGFVAGLLFGIPCLRNIRKKIWEVKLFWVSLSIYTGLLGFAILWNI 1270
            L   +K +FD +D  G   +  +  L+ L+       +P  +    + R    K     G VT+++F         R F   +  RD     +    L L   P L    +     E L  E +R        + Y D Y+C PPP FI ++ + ++  FV++ + +  E  P+        IP  S  I+   KR EIWRF  YM++H G+LH+ FN  +QL+ G+PLE+VH   R+  +Y SGVLAGSL +SI D +  LVG+SGG YAL+ AH A V++N+ +++                GV++LL ++ F++ D G ++Y R   D             +Q  TA      +H+ G +AGL  G+  L++  +K+ E  L+W++L  Y  L+ FAI +NI
Sbjct:   86 LRDKWKLLFDMFDPEGFGEISVEEFLEALKSPEFLSQVPMNKRELLLERAKKAKLPTGPGYVTFQDFVNVMSGKRTRSFKCAVHHRDREVCSENDFQLVLNE-PPLFRKMVHAVAMEILPEERDR--------KYYADRYTCCPPPFFIILVTLVELGFFVYHSV-VTGEAAPRG------PIPSDSMFIYRPDKRHEIWRFLFYMVLHAGWLHLGFNVAVQLVFGLPLEMVHGSTRIACIYFSGVLAGSLGTSIFDPDVFLVGASGGVYALLAAHLANVLLNYHQMRY---------------GVIKLLHILVFVSFDFGFAIYARYAGDELQLGSSSEFLAIDQAETAGAVSYVAHLAGAIAGLTIGLLVLKSFEQKLHEQLLWWIALGTYLALVVFAIAFNI 459
[Close]
BLAST of rhomboid-like protein vs. Ensembl Fly
Match: stet (gene:FBgn0020248 transcript:FBtr0072713)

HSP 1 Score: 137.887 bits (346), Expect = 2.397e-36
Identity = 111/329 (33.74%), Postives = 169/329 (51.37%), Query Frame = 2 
Query:  335 RLFMLNIEPRDISFAKKILISLALKSCPDLINSYLPGSCEENLMREEERHKLKNELAESYLDAYSCYPPPVFIPIILVAQMASFVFYGLQLIHEDDPKNMLSWTTGIPRKSPLIFDVHKRIEIWRFFSYMLIHQGYLHIIFNCXXXXXXXXXXXXVHKFWRVGPVYXXXXXXXXXXXXIIDKNSKLVGSSGGSYALIGAHFAIVIMNWDELQRDWLKIKVNFLNFVASGVVRLLFLITFLTADLGTSLYRR--------------LGLDITEQTSTAS---HIGGFVAGLLFGIPCLRNIRKKIWEVKLFWVSLSIYTGLLGFAILWNI 1270
            R F   +  RD     +    L L   P L    +     E L  E +R        + Y D Y+C PPP FI ++ + ++  FV++ + +  E  P+        IP  S  I+   KR EIWRF  YM++H G+LH+ FN  +QL+ G+PLE+VH   R+  +Y SGVLAGSL +SI D +  LVG+SGG YAL+ AH A V++N+ +++                GV++LL ++ F++ D G ++Y R              L +D  E     S   H+ G +AGL  G+  L++  +K+ E  L+W++L  Y  L+ FAI +NI
Sbjct:    7 RSFKCAVHHRDREVCSENDFQLVLNE-PPLFRKMVHAVAMEILPEERDR--------KYYADRYTCCPPPFFIILVTLVELGFFVYHSV-VTGEAAPRG------PIPSDSMFIYRPDKRHEIWRFLFYMVLHAGWLHLGFNVAVQLVFGLPLEMVHGSTRIACIYFSGVLAGSLGTSIFDPDVFLVGASGGVYALLAAHLANVLLNYHQMRY---------------GVIKLLHILVFVSFDFGFAIYARYAGDELQLGSSSEFLAIDQAETAGAVSYVAHLAGAIAGLTIGLLVLKSFEQKLHEQLLWWIALGTYLALVVFAIAFNI 304
[Close]
BLAST of rhomboid-like protein vs. Ensembl Fly
Match: rho (gene:FBgn0004635 transcript:FBtr0072694)

HSP 1 Score: 109.768 bits (273), Expect = 4.480e-26
Identity = 82/247 (33.20%), Postives = 135/247 (54.66%), Query Frame = 2 
Query:  542 PVFIPIILVAQMASFVFYGLQLIHEDDPKNMLSWTTGIPRKSPLIFDVHKRIEIWRFFSYMLIHQGYLHIIFNCXXXXXXXXXXXXVHKFWRVGPVYXXXXXXXXXXXXIIDKNSKLVGSSGGSYALIGAHFAIVIMNWDELQRDWLKIKVNFLNFVASGVVRLLFLITFLTADLGTSLYRRL----GLDITEQTSTASHIGGFVAGLLFGIPCLRNIRKKIWEVKLFWVSLSIYTGLLGFAILWNI 1270
            P FI +I + ++A F +    +     P         IP  S L++   +R+++WRFFSYM +H  + H+ FN +IQL  GIPLE++H   R+G +Y++GV AGSL +S++D    LVG+SGG YAL+ AH A + +N+  ++               S   +L  ++ F++ DLG +LY +           Q S  +H+ G +AGL  G   L+N   + +E  ++W++L +Y     FAI++N+
Sbjct:  102 PWFILVISIIEIAIFAYDRYTM-----PAQNFGLPVPIPSDSVLVYRPDRRLQVWRFFSYMFLHANWFHLGFNIVIQLFFGIPLEVMHGTARIGVIYMAGVFAGSLGTSVVDSEVFLVGASGGVYALLAAHLANITLNYAHMK---------------SASTQLGSVVIFVSCDLGYALYTQYFDGSAFAKGPQVSYIAHLTGALAGLTIGFLVLKNFGHREYEQLIWWLALGVYCAFTVFAIVFNL 328
[Close]
BLAST of rhomboid-like protein vs. Ensembl Zebrafish
Match: rhbdl2 (rhomboid, veinlet-like 2 (Drosophila) [Source:ZFIN;Acc:ZDB-GENE-040426-732])

HSP 1 Score: 145.591 bits (366), Expect = 2.270e-39
Identity = 116/276 (42.03%), Postives = 164/276 (59.42%), Query Frame = 2 
Query:  467 REEERHK------LKNELAESYLDAYSCYPPPVFIPIILVAQMASFVFYGLQLIHEDDPKNMLSWTTGIPRKSPLIFDVHKRIEIWRFFSYMLIHQGYLHIIFNCXXXXXXXXXXXXVHKFWRVGPVYXXXXXXXXXXXXIIDKNSKLVGSSGGSYALIGAHFAIVIMNWDELQRDWLKIKVNFLNFVASGVVRLLFLITFLTADLGTSLYRRLGL-DITEQTSTASHIGGFVAGLLFGIPCLRNIRKKIWEVKLFWVSLSIYTGLLGFAILWNIF 1273
            R E+ HK      L  EL E+YL+  +C PPP+FI +I +A++A F++Y +        K  ++  TGI   SPL +   +R E WRF SYM +H G  HI+ N L+QLLLGIPLELVHK + VG VY+ GVLAGSLASSI D  S LVG+SGG YAL+G +F   I+N+ E++             V  GV R+L ++  +  D+G +LYRR  + +   + S  +HIGG +AG+  G     N  K++ +   FW+ +  Y   L FA+++NIF
Sbjct:   30 RVEKFHKNVSKWMLPEELHETYLERANCCPPPIFIILISLAELAVFIYYAVW----KPQKQWITLGTGI-WDSPLTYRPEQRKEAWRFVSYMFVHAGVEHIMGNLLMQLLLGIPLELVHKGFEVGMVYMCGVLAGSLASSIFDPFSALVGASGGVYALMGGYFMNAIVNFREMR-------------VLLGVFRILLIVLIVGTDVGFALYRRFIVHEAGLKVSFVAHIGGGIAGMTIGYVFFTNYNKELLKDPRFWMCIVGYIVFLLFAVIFNIF 287
[Close]
BLAST of rhomboid-like protein vs. Ensembl Zebrafish
Match: rhbdl2 (rhomboid, veinlet-like 2 (Drosophila) [Source:ZFIN;Acc:ZDB-GENE-040426-732])

HSP 1 Score: 145.591 bits (366), Expect = 2.270e-39
Identity = 116/276 (42.03%), Postives = 164/276 (59.42%), Query Frame = 2 
Query:  467 REEERHK------LKNELAESYLDAYSCYPPPVFIPIILVAQMASFVFYGLQLIHEDDPKNMLSWTTGIPRKSPLIFDVHKRIEIWRFFSYMLIHQGYLHIIFNCXXXXXXXXXXXXVHKFWRVGPVYXXXXXXXXXXXXIIDKNSKLVGSSGGSYALIGAHFAIVIMNWDELQRDWLKIKVNFLNFVASGVVRLLFLITFLTADLGTSLYRRLGL-DITEQTSTASHIGGFVAGLLFGIPCLRNIRKKIWEVKLFWVSLSIYTGLLGFAILWNIF 1273
            R E+ HK      L  EL E+YL+  +C PPP+FI +I +A++A F++Y +        K  ++  TGI   SPL +   +R E WRF SYM +H G  HI+ N L+QLLLGIPLELVHK + VG VY+ GVLAGSLASSI D  S LVG+SGG YAL+G +F   I+N+ E++             V  GV R+L ++  +  D+G +LYRR  + +   + S  +HIGG +AG+  G     N  K++ +   FW+ +  Y   L FA+++NIF
Sbjct:   30 RVEKFHKNVSKWMLPEELHETYLERANCCPPPIFIILISLAELAVFIYYAVW----KPQKQWITLGTGI-WDSPLTYRPEQRKEAWRFVSYMFVHAGVEHIMGNLLMQLLLGIPLELVHKGFEVGMVYMCGVLAGSLASSIFDPFSALVGASGGVYALMGGYFMNAIVNFREMR-------------VLLGVFRILLIVLIVGTDVGFALYRRFIVHEAGLKVSFVAHIGGGIAGMTIGYVFFTNYNKELLKDPRFWMCIVGYIVFLLFAVIFNIF 287
[Close]
BLAST of rhomboid-like protein vs. Ensembl Zebrafish
Match: rhbdl2 (rhomboid, veinlet-like 2 (Drosophila) [Source:ZFIN;Acc:ZDB-GENE-040426-732])

HSP 1 Score: 145.591 bits (366), Expect = 2.270e-39
Identity = 116/276 (42.03%), Postives = 164/276 (59.42%), Query Frame = 2 
Query:  467 REEERHK------LKNELAESYLDAYSCYPPPVFIPIILVAQMASFVFYGLQLIHEDDPKNMLSWTTGIPRKSPLIFDVHKRIEIWRFFSYMLIHQGYLHIIFNCXXXXXXXXXXXXVHKFWRVGPVYXXXXXXXXXXXXIIDKNSKLVGSSGGSYALIGAHFAIVIMNWDELQRDWLKIKVNFLNFVASGVVRLLFLITFLTADLGTSLYRRLGL-DITEQTSTASHIGGFVAGLLFGIPCLRNIRKKIWEVKLFWVSLSIYTGLLGFAILWNIF 1273
            R E+ HK      L  EL E+YL+  +C PPP+FI +I +A++A F++Y +        K  ++  TGI   SPL +   +R E WRF SYM +H G  HI+ N L+QLLLGIPLELVHK + VG VY+ GVLAGSLASSI D  S LVG+SGG YAL+G +F   I+N+ E++             V  GV R+L ++  +  D+G +LYRR  + +   + S  +HIGG +AG+  G     N  K++ +   FW+ +  Y   L FA+++NIF
Sbjct:   30 RVEKFHKNVSKWMLPEELHETYLERANCCPPPIFIILISLAELAVFIYYAVW----KPQKQWITLGTGI-WDSPLTYRPEQRKEAWRFVSYMFVHAGVEHIMGNLLMQLLLGIPLELVHKGFEVGMVYMCGVLAGSLASSIFDPFSALVGASGGVYALMGGYFMNAIVNFREMR-------------VLLGVFRILLIVLIVGTDVGFALYRRFIVHEAGLKVSFVAHIGGGIAGMTIGYVFFTNYNKELLKDPRFWMCIVGYIVFLLFAVIFNIF 287
[Close]
BLAST of rhomboid-like protein vs. Ensembl Zebrafish
Match: rhbdl2 (rhomboid, veinlet-like 2 (Drosophila) [Source:ZFIN;Acc:ZDB-GENE-040426-732])

HSP 1 Score: 145.591 bits (366), Expect = 2.270e-39
Identity = 116/276 (42.03%), Postives = 164/276 (59.42%), Query Frame = 2 
Query:  467 REEERHK------LKNELAESYLDAYSCYPPPVFIPIILVAQMASFVFYGLQLIHEDDPKNMLSWTTGIPRKSPLIFDVHKRIEIWRFFSYMLIHQGYLHIIFNCXXXXXXXXXXXXVHKFWRVGPVYXXXXXXXXXXXXIIDKNSKLVGSSGGSYALIGAHFAIVIMNWDELQRDWLKIKVNFLNFVASGVVRLLFLITFLTADLGTSLYRRLGL-DITEQTSTASHIGGFVAGLLFGIPCLRNIRKKIWEVKLFWVSLSIYTGLLGFAILWNIF 1273
            R E+ HK      L  EL E+YL+  +C PPP+FI +I +A++A F++Y +        K  ++  TGI   SPL +   +R E WRF SYM +H G  HI+ N L+QLLLGIPLELVHK + VG VY+ GVLAGSLASSI D  S LVG+SGG YAL+G +F   I+N+ E++             V  GV R+L ++  +  D+G +LYRR  + +   + S  +HIGG +AG+  G     N  K++ +   FW+ +  Y   L FA+++NIF
Sbjct:   30 RVEKFHKNVSKWMLPEELHETYLERANCCPPPIFIILISLAELAVFIYYAVW----KPQKQWITLGTGI-WDSPLTYRPEQRKEAWRFVSYMFVHAGVEHIMGNLLMQLLLGIPLELVHKGFEVGMVYMCGVLAGSLASSIFDPFSALVGASGGVYALMGGYFMNAIVNFREMR-------------VLLGVFRILLIVLIVGTDVGFALYRRFIVHEAGLKVSFVAHIGGGIAGMTIGYVFFTNYNKELLKDPRFWMCIVGYIVFLLFAVIFNIF 287
[Close]
BLAST of rhomboid-like protein vs. Ensembl Zebrafish
Match: rhbdl2 (rhomboid, veinlet-like 2 (Drosophila) [Source:ZFIN;Acc:ZDB-GENE-040426-732])

HSP 1 Score: 145.591 bits (366), Expect = 2.270e-39
Identity = 116/276 (42.03%), Postives = 164/276 (59.42%), Query Frame = 2 
Query:  467 REEERHK------LKNELAESYLDAYSCYPPPVFIPIILVAQMASFVFYGLQLIHEDDPKNMLSWTTGIPRKSPLIFDVHKRIEIWRFFSYMLIHQGYLHIIFNCXXXXXXXXXXXXVHKFWRVGPVYXXXXXXXXXXXXIIDKNSKLVGSSGGSYALIGAHFAIVIMNWDELQRDWLKIKVNFLNFVASGVVRLLFLITFLTADLGTSLYRRLGL-DITEQTSTASHIGGFVAGLLFGIPCLRNIRKKIWEVKLFWVSLSIYTGLLGFAILWNIF 1273
            R E+ HK      L  EL E+YL+  +C PPP+FI +I +A++A F++Y +        K  ++  TGI   SPL +   +R E WRF SYM +H G  HI+ N L+QLLLGIPLELVHK + VG VY+ GVLAGSLASSI D  S LVG+SGG YAL+G +F   I+N+ E++             V  GV R+L ++  +  D+G +LYRR  + +   + S  +HIGG +AG+  G     N  K++ +   FW+ +  Y   L FA+++NIF
Sbjct:   30 RVEKFHKNVSKWMLPEELHETYLERANCCPPPIFIILISLAELAVFIYYAVW----KPQKQWITLGTGI-WDSPLTYRPEQRKEAWRFVSYMFVHAGVEHIMGNLLMQLLLGIPLELVHKGFEVGMVYMCGVLAGSLASSIFDPFSALVGASGGVYALMGGYFMNAIVNFREMR-------------VLLGVFRILLIVLIVGTDVGFALYRRFIVHEAGLKVSFVAHIGGGIAGMTIGYVFFTNYNKELLKDPRFWMCIVGYIVFLLFAVIFNIF 287
[Close]
BLAST of rhomboid-like protein vs. Ensembl Xenopus
Match: eif4a1 (eukaryotic translation initiation factor 4A1 [Source:Xenbase;Acc:XB-GENE-491256])

HSP 1 Score: 141.354 bits (355), Expect = 9.751e-38
Identity = 104/279 (37.28%), Postives = 160/279 (57.35%), Query Frame = 2 
Query:  440 PGSCEENLMREEERHKLKNELAESYLDAYSCYPPPVFIPIILVAQMASFVFYGLQLIHEDDPKNMLSWTTGIPRKSPLIFDVHKRIEIWRFFSYMLIHQGYLHIIFNCXXXXXXXXXXXXVHKFWRVGPVYXXXXXXXXXXXXIIDKNSKLVGSSGGSYALIGAHFAIVIMNWDELQRDWLKIKVNFLNFVASGVVRLLFLITFLTADLGTSLYRR-LGLDITEQTSTASHIGGFVAGLLFGIPCLRNIRKKIWEVKLFWVSLSIYTGLLGFAILWNIF 1273
            P +C + +        L     ++YL+  +C PPP+FI  + +A++A F++Y + +      K  ++  TG+   SP I+   KR E WRF SYM++H G  HII N  +QLLLGIPLELVHK  R+G VYL+GV+ GSLASS+ D    LVG+SGG YALIG +F  V++N+ ++   +             G+ R+L +IT +  D+G +LYRR +  +  ++ S  +H  G +AG+  G        K + +   FW+ ++ Y   + FA+L+NIF
Sbjct:   25 PKTCCDKIHETISNWILPTNQRDTYLERANCLPPPIFIISVSIAELAVFIYYAVWMPQ----KQWITLDTGV-WNSPFIYRPDKREEAWRFISYMMVHAGMTHIIGNLALQLLLGIPLELVHKGHRIGLVYLAGVIGGSLASSVFDSGLALVGASGGVYALIGGYFMNVLVNFKDMIPLF-------------GIFRILVIITIVGTDVGFALYRRYISHETGQKVSFVAHFAGGLAGMSIGYTVFSCFDKNLIKDPRFWICIAAYAAFVIFAVLFNIF 285
[Close]
BLAST of rhomboid-like protein vs. Ensembl Mouse
Match: Rhbdl2 (rhomboid like 2 [Source:MGI Symbol;Acc:MGI:3608413])

HSP 1 Score: 145.591 bits (366), Expect = 2.314e-39
Identity = 111/263 (42.21%), Postives = 157/263 (59.70%), Query Frame = 2 
Query:  488 LKNELAESYLDAYSCYPPPVFIPIILVAQMASFVFYGLQLIHEDDPKNMLSWTTGIPRKSPLIFDVHKRIEIWRFFSYMLIHQGYLHIIFNCXXXXXXXXXXXXVHKFWRVGPVYXXXXXXXXXXXXIIDKNSKLVGSSGGSYALIGAHFAIVIMNWDELQRDWLKIKVNFLNFVASGVVRLLFLITFLTADLGTSLYRRLGLDIT-EQTSTASHIGGFVAGLLFGIPCLRNIRKKIWEVKLFWVSLSIYTGLLGFAILWNIF 1273
            L   +  +YL+  +C PPP+FI +I +A++A F++Y +        K  ++  TGI  +SPL +   KR E WRF SYML+H G  HI+ N L+Q++LGIPLE+VHK  RVG VYL+GVLAGSLASSI D    LVG+SGG YAL+G +F  VI+N+ E+               A G+VRLL +I  + +D+G +LYRR  +       S A+HI G  AG+  G        K + +   FW++++ Y   L FA+ +NIF
Sbjct:   53 LPEPVRRTYLERANCLPPPLFIILISLAELAVFIYYAVW----KPQKQWITLDTGI-LESPLTYCPEKREEAWRFISYMLVHAGVQHIVGNLLMQIVLGIPLEMVHKGLRVGLVYLAGVLAGSLASSIFDPLKSLVGASGGVYALMGGYFMNVIVNFREM-------------IPAFGIVRLLVIILIVASDMGFALYRRFFVPANGSPVSFAAHIAGGFAGMSIGYTVFSCFDKTLLKDPRFWIAIAAYVACLLFAVFFNIF 297
[Close]
BLAST of rhomboid-like protein vs. Ensembl Mouse
Match: Rhbdl2 (rhomboid like 2 [Source:MGI Symbol;Acc:MGI:3608413])

HSP 1 Score: 145.591 bits (366), Expect = 2.314e-39
Identity = 111/263 (42.21%), Postives = 157/263 (59.70%), Query Frame = 2 
Query:  488 LKNELAESYLDAYSCYPPPVFIPIILVAQMASFVFYGLQLIHEDDPKNMLSWTTGIPRKSPLIFDVHKRIEIWRFFSYMLIHQGYLHIIFNCXXXXXXXXXXXXVHKFWRVGPVYXXXXXXXXXXXXIIDKNSKLVGSSGGSYALIGAHFAIVIMNWDELQRDWLKIKVNFLNFVASGVVRLLFLITFLTADLGTSLYRRLGLDIT-EQTSTASHIGGFVAGLLFGIPCLRNIRKKIWEVKLFWVSLSIYTGLLGFAILWNIF 1273
            L   +  +YL+  +C PPP+FI +I +A++A F++Y +        K  ++  TGI  +SPL +   KR E WRF SYML+H G  HI+ N L+Q++LGIPLE+VHK  RVG VYL+GVLAGSLASSI D    LVG+SGG YAL+G +F  VI+N+ E+               A G+VRLL +I  + +D+G +LYRR  +       S A+HI G  AG+  G        K + +   FW++++ Y   L FA+ +NIF
Sbjct:   53 LPEPVRRTYLERANCLPPPLFIILISLAELAVFIYYAVW----KPQKQWITLDTGI-LESPLTYCPEKREEAWRFISYMLVHAGVQHIVGNLLMQIVLGIPLEMVHKGLRVGLVYLAGVLAGSLASSIFDPLKSLVGASGGVYALMGGYFMNVIVNFREM-------------IPAFGIVRLLVIILIVASDMGFALYRRFFVPANGSPVSFAAHIAGGFAGMSIGYTVFSCFDKTLLKDPRFWIAIAAYVACLLFAVFFNIF 297
[Close]
BLAST of rhomboid-like protein vs. Ensembl Mouse
Match: Rhbdl3 (rhomboid like 3 [Source:MGI Symbol;Acc:MGI:2179276])

HSP 1 Score: 132.109 bits (331), Expect = 1.527e-33
Identity = 114/380 (30.00%), Postives = 194/380 (51.05%), Query Frame = 2 
Query:  164 DQTFKTMFDEYD--SMG-MPTQCLLKLLRRDSLGIPRQRLNRFIMRLDANKDGRVTYEEFRLFMLNIEPRDISFAKKILISLALKSCPDLINSYLPG-SCEENLMREEERHKLKNELAES-YLDAYSCYPPPVFIPIILVAQMASFVFYGLQLIHEDDPKNMLSWTTGIPR--KSPLIFDVHKRIEIWRFFSYMLIHQGYLHIIFNCXXXXXXXXXXXXVHKFWRVGPVYXXXXXXXXXXXXIIDKNSKLVGSSGGSYALIGAHFAIVIMNWDELQRDWLKIKVNFLNFVASGVVRLLFLITFLTADLGTSLYRRL---GLDITEQTSTASHIGGFVAGLLFGIPCLRNIRKKIWEVKLFWVSLSIYTGLLGFAILWNIF 1273
            +  +K +F+++D  S G + T     LL   S  +   +    +   D++ DG++ Y++F   M N   R  SF + IL      S   L+     G S  + L+R      L  E+    Y D+Y+C PPP F+  I + ++A F++ G+ L       +        PR  K+ L++    R + WR+ +Y+ +H G   +  N  +QLL+G+PLE+VH   R+G VY++GV+AGSLA S+ D  + +VGSSGG YAL+ AH A ++MNW  +       K  F       ++R+   +  ++ + G +++ R            S  +H+GG   G+  G+  LRN  +++ +  L+W+ +++YT  + FA+ WNIF
Sbjct:   36 EDHWKVLFEKFDPGSTGYISTGKFRSLLESHSSKLDPHKKEVLLALADSHADGQICYQDFVNLMSN--KRSNSFRQAILQGNRRLSSKALLEE--KGLSLSQRLIRHVAYETLPREIDRKWYYDSYTCCPPPWFMITITLLEVALFLYNGVLL-------DQFVLQVTHPRYLKNSLVYHPQLRAQAWRYVTYIFMHAGVEQLGLNVALQLLVGVPLEMVHGATRIGLVYVAGVVAGSLAVSVADMTAPVVGSSGGVYALVSAHLANIVMNWSGM-------KCQF------KLLRMAVALICMSMEFGRAVWLRFHPSAYPPCPHPSFVAHLGGVAVGITLGVVVLRNYEQRLQDQSLWWIFVTMYTIFVLFAVFWNIF 391
[Close]
BLAST of rhomboid-like protein vs. Ensembl Mouse
Match: Rhbdl1 (rhomboid like 1 [Source:MGI Symbol;Acc:MGI:2384891])

HSP 1 Score: 112.464 bits (280), Expect = 8.130e-27
Identity = 107/358 (29.89%), Postives = 182/358 (50.84%), Query Frame = 2 
Query:  233 LLRRDSLGIPRQRLNRFIMRLDANKDGRVTYEEFRLFMLNIEPRDISFAKKILISLALKSCP--DLINSYLPG-SCEENLMREEERHKLKNELAES-YLDAYSCYPPPVFIPIILVAQMASFVFYGLQL----IHEDDPKNMLSWTTGIPRKSPLIFDVHKRIEIWRFFSYMLIHQGYLHIIFNCXXXXXXXXXXXXVHKFWRVGPVYXXXXXXXXXXXXIIDKNSKLVGSSGGSYALIGAHFAIVIMNWDELQRDWLKIKVNFLNFVASGVVRLLFLITFLTADLGTSLYRRLGLDIT---EQTSTASHIGGFVAGLLFGIPCLRNIRKKIWEVKLFWVSLSIYTGLLGFAILWNIF 1273
            L+    L +   +L+  +    +N+ G+V Y+E    ++++     S + K  I+   ++ P   L++   PG S  +  +R      L  E+    Y   +   PPPVF+  + +AQ+  F+ YG +L    +    P+ M         KSPL++    R   WRF +YM +H G   + FN L+QL++G+PLE+VH   R+  +YL+GVLAGSL  SI D  + +VG SGG YAL  AH A V+MNW  ++  +              ++R++  +  +++++G +++ R    +     Q S  +H+ G V G+  G+  LR+  +++ +   +WV L  Y   L FAI WN+F
Sbjct:   31 LVHSHELPLDPTKLDMLVALAQSNERGQVCYQE----LVDLISSKRSSSFKRAIANGQRALPRDGLLDE--PGLSVYKRFVRYVAYEILPCEVDRRWYFYRHRTCPPPVFMASVTLAQIIVFLCYGARLNKWVLQTYHPEYM---------KSPLVYHPGHRARAWRFLTYMFMHVGLEQLGFNALLQLMIGVPLEMVHGVLRISLLYLAGVLAGSLTVSITDMRAPVVGGSGGVYALCSAHLANVVMNWAGMRCPY-------------KLLRMVLALVCMSSEVGRAVWLRFSPPLPASGPQPSFMAHLAGAVVGVSMGLTILRSYEERLRDQCGWWVVLLAYGTFLLFAIFWNVF 360
[Close]
BLAST of rhomboid-like protein vs. Ensembl Mouse
Match: Rhbdl1 (rhomboid like 1 [Source:MGI Symbol;Acc:MGI:2384891])

HSP 1 Score: 107.071 bits (266), Expect = 6.540e-25
Identity = 100/358 (27.93%), Postives = 174/358 (48.60%), Query Frame = 2 
Query:  233 LLRRDSLGIPRQRLNRFIMRLDANKDGRVTYEEFRLFMLNIEPRDISFAKKILISLALKSCP--DLINSYLPG-SCEENLMREEERHKLKNELAES-YLDAYSCYPPPVFIPIILVAQMASFVFYGLQL----IHEDDPKNMLSWTTGIPRKSPLIFDVHKRIEIWRFFSYMLIHQGYLHIIFNCXXXXXXXXXXXXVHKFWRVGPVYXXXXXXXXXXXXIIDKNSKLVGSSGGSYALIGAHFAIVIMNWDELQRDWLKIKVNFLNFVASGVVRLLFLITFLTADLGTSLYRRLGLDITE---QTSTASHIGGFVAGLLFGIPCLRNIRKKIWEVKLFWVSLSIYTGLLGFAILWNIF 1273
            L+    L +   +L+  +    +N+ G+V Y+E    +  +     S + K  I+   ++ P   L++   PG S  +  +R      L  E+    Y   +   PPPVF+  + +AQ+  F+ YG +L    +    P+ M         KSPL++    R   WRF +YM +H G   + FN L+QL++G+PLE+VH   R+  +YL+GV        + D  + +VG SGG YAL  AH A V+MNW  ++  +              ++R++  +  +++++G +++ R    +     Q S  +H+ G V G+  G+  LR+  +++ +   +WV L  Y   L FAI WN+F
Sbjct:   31 LVHSHELPLDPTKLDMLVALAQSNERGQVCYQELVDLVSAMISSKRSSSFKRAIANGQRALPRDGLLDE--PGLSVYKRFVRYVAYEILPCEVDRRWYFYRHRTCPPPVFMASVTLAQIIVFLCYGARLNKWVLQTYHPEYM---------KSPLVYHPGHRARAWRFLTYMFMHVGLEQLGFNALLQLMIGVPLEMVHGVLRISLLYLAGV--------LADMRAPVVGGSGGVYALCSAHLANVVMNWAGMRCPY-------------KLLRMVLALVCMSSEVGRAVWLRFSPPLPASGPQPSFMAHLAGAVVGVSMGLTILRSYEERLRDQCGWWVVLLAYGTFLLFAIFWNVF 356
[Close]
BLAST of rhomboid-like protein vs. UniProt/SwissProt
Match: sp|A2AGA4|RHBL2_MOUSE (Rhomboid-related protein 2 OS=Mus musculus OX=10090 GN=Rhbdl2 PE=1 SV=1)

HSP 1 Score: 145.591 bits (366), Expect = 1.619e-38
Identity = 111/263 (42.21%), Postives = 157/263 (59.70%), Query Frame = 2 
Query:  488 LKNELAESYLDAYSCYPPPVFIPIILVAQMASFVFYGLQLIHEDDPKNMLSWTTGIPRKSPLIFDVHKRIEIWRFFSYMLIHQGYLHIIFNCXXXXXXXXXXXXVHKFWRVGPVYXXXXXXXXXXXXIIDKNSKLVGSSGGSYALIGAHFAIVIMNWDELQRDWLKIKVNFLNFVASGVVRLLFLITFLTADLGTSLYRRLGLDIT-EQTSTASHIGGFVAGLLFGIPCLRNIRKKIWEVKLFWVSLSIYTGLLGFAILWNIF 1273
            L   +  +YL+  +C PPP+FI +I +A++A F++Y +        K  ++  TGI  +SPL +   KR E WRF SYML+H G  HI+ N L+Q++LGIPLE+VHK  RVG VYL+GVLAGSLASSI D    LVG+SGG YAL+G +F  VI+N+ E+               A G+VRLL +I  + +D+G +LYRR  +       S A+HI G  AG+  G        K + +   FW++++ Y   L FA+ +NIF
Sbjct:   53 LPEPVRRTYLERANCLPPPLFIILISLAELAVFIYYAVW----KPQKQWITLDTGI-LESPLTYCPEKREEAWRFISYMLVHAGVQHIVGNLLMQIVLGIPLEMVHKGLRVGLVYLAGVLAGSLASSIFDPLKSLVGASGGVYALMGGYFMNVIVNFREM-------------IPAFGIVRLLVIILIVASDMGFALYRRFFVPANGSPVSFAAHIAGGFAGMSIGYTVFSCFDKTLLKDPRFWIAIAAYVACLLFAVFFNIF 297
[Close]
BLAST of rhomboid-like protein vs. UniProt/SwissProt
Match: sp|P58872|RHBL3_HUMAN (Rhomboid-related protein 3 OS=Homo sapiens OX=9606 GN=RHBDL3 PE=2 SV=1)

HSP 1 Score: 139.043 bits (349), Expect = 4.020e-35
Identity = 113/378 (29.89%), Postives = 196/378 (51.85%), Query Frame = 2 
Query:  164 DQTFKTMFDEYDSMG---MPTQCLLKLLRRDSLGIPRQRLNRFIMRLDANKDGRVTYEEFRLFMLNIEPRDISFAKKILISLALKSCPDLINSYLPG-SCEENLMREEERHKLKNELAES-YLDAYSCYPPPVFIPIILVAQMASFVFYGLQLIHEDDPKNMLSWTTGIPRKSPLIFDVHKRIEIWRFFSYMLIHQGYLHIIFNCXXXXXXXXXXXXVHKFWRVGPVYXXXXXXXXXXXXIIDKNSKLVGSSGGSYALIGAHFAIVIMNWDELQRDWLKIKVNFLNFVASGVVRLLFLITFLTADLGTSLYRRL---GLDITEQTSTASHIGGFVAGLLFGIPCLRNIRKKIWEVKLFWVSLSIYTGLLGFAILWNIF 1273
            +  +K +FD++D      + T     LL   S  +   +    +   D++ DG++ Y++F   M N   R  SF + IL      S   L+     G S  + L+R      L  E+    Y D+Y+C PPP F+  + + ++A F++ G+ L      + +L  T     K+ L++    R ++WR+ +Y+ +H G  H+  N ++QLL+G+PLE+VH   R+G VY++GV+AGSLA S+ D  + +VGSSGG YAL+ AH A ++MNW  +       K  F       ++R+   +  ++ + G +++ R            S  +H+GG   G+  G+  LRN  +++ +  L+W+ +++YT  + FA+ WNIF
Sbjct:   36 EDHWKVLFDQFDPGNTGYISTGKFRSLLESHSSKLDPHKREVLLALADSHADGQIGYQDFVSLMSN--KRSNSFRQAILQGNRRLSSKALLEE--KGLSLSQRLIRHVAYETLPREIDRKWYYDSYTCCPPPWFMITVTLLEVAFFLYNGVSL-----GQFVLQVTHPRYLKNSLVYHPQLRAQVWRYLTYIFMHAGIEHLGLNVVLQLLVGVPLEMVHGATRIGLVYVAGVVAGSLAVSVADMTAPVVGSSGGVYALVSAHLANIVMNWSGM-------KCQF------KLLRMAVALICMSMEFGRAVWLRFHPSAYPPCPHPSFVAHLGGVAVGITLGVVVLRNYEQRLQDQSLWWIFVAMYTVFVLFAVFWNIF 391
[Close]
BLAST of rhomboid-like protein vs. UniProt/SwissProt
Match: sp|Q19821|RHOM1_CAEEL (Rhomboid-related protein 1 OS=Caenorhabditis elegans OX=6239 GN=rom-1 PE=2 SV=2)

HSP 1 Score: 134.806 bits (338), Expect = 5.775e-34
Identity = 101/267 (37.83%), Postives = 142/267 (53.18%), Query Frame = 2 
Query:  506 ESYLDAYSCYPPPVFIPIILVAQMASFVFY----GLQLIHEDDPKNMLSWTTGIPRKSPLIFDVHKRIEIWRFFSYMLIHQGYLHIIFNCXXXXXXXXXXXXVHKFWRVGPVYXXXXXXXXXXXXIIDKNSKLVGSSGGSYALIGAHFAIVIMNWDELQRDWLKIKVNFLNFVASGVVRLLFLITFLTADLGTSLYRRLGLDITEQTSTASHIGGFVAGLLFGIPCLRNIRKKIWEVKLFWVSLSIYTGLLGFAILWNIFYPGYNES 1294
             SY+D+YS  PPP+F+ +I + Q+  F FY    G + I  D     +      P     IF    R E WRF SYM +H G  H++ N +IQLL+GIPLE+ HK WR+GP+YL  V +GSL    ID NS LVG+S G YALI AH A VI+NW E+   W               +R+L L  F+  D G +++RR   +  +  S  +HI G V GL FG   L N+ +   E  + +V L +Y+      I++ I    Y+++
Sbjct:   99 HSYIDSYSWCPPPIFMLLITIIQVGIFFFYWESDGGRSIWTDCAGCFVHHNHTAP--GIFIFAPKLRGEAWRFTSYMFLHAGLNHLLGNVIIQLLVGIPLEVAHKIWRIGPIYLLAVTSGSLLQYAIDPNSLLVGASAGVYALIFAHVANVILNWHEMPLRW---------------IRVLVLFVFIFLDFGGAIHRRFYTNDCDSVSHLAHIAGAVTGLFFGYVVLYNVVEHRIEKIIRYVCLFLYSAFFATTIIFVIVRQPYSKN 348
[Close]
BLAST of rhomboid-like protein vs. UniProt/SwissProt
Match: sp|Q9NX52|RHBL2_HUMAN (Rhomboid-related protein 2 OS=Homo sapiens OX=9606 GN=RHBDL2 PE=1 SV=2)

HSP 1 Score: 133.265 bits (334), Expect = 6.291e-34
Identity = 107/256 (41.80%), Postives = 153/256 (59.77%), Query Frame = 2 
Query:  509 SYLDAYSCYPPPVFIPIILVAQMASFVFYGLQLIHEDDPKNMLSWTTGIPRKSPLIFDVHKRIEIWRFFSYMLIHQGYLHIIFNCXXXXXXXXXXXXVHKFWRVGPVYXXXXXXXXXXXXIIDKNSKLVGSSGGSYALIGAHFAIVIMNWDELQRDWLKIKVNFLNFVASGVVRLLFLITFLTADLGTSLYRRLGL-DITEQTSTASHIGGFVAGLLFGIPCLRNIRKKIWEVKLFWVSLSIYTGLLGFAILWNIF 1273
            +YL+  +C+PPPVFI  I +A++A F++Y +        K  ++  TGI  +SP I+   KR E WRF SYML+H G  HI+ N  +QL+LGIPLE+VHK  RVG VYL+GV+AGSLASSI D    LVG+SGG YAL+G +F  V++N+ E+               A G+ RLL +I  +  D+G +LYRR  + +     S A+HI G  AG+  G        K + +   FW++++ Y   + FA+ +NIF
Sbjct:   61 TYLERANCFPPPVFIISISLAELAVFIYYAVW----KPQKQWITLDTGI-LESPFIYSPEKREEAWRFISYMLVHAGVQHILGNLCMQLVLGIPLEMVHKGLRVGLVYLAGVIAGSLASSIFDPLRYLVGASGGVYALMGGYFMNVLVNFQEM-------------IPAFGIFRLLIIILIIVLDMGFALYRRFFVPEDGSPVSFAAHIAGGFAGMSIGYTVFSCFDKALLKDPRFWIAIAAYLACVLFAVFFNIF 298
[Close]
BLAST of rhomboid-like protein vs. UniProt/SwissProt
Match: sp|P58873|RHBL3_MOUSE (Rhomboid-related protein 3 OS=Mus musculus OX=10090 GN=Rhbdl3 PE=2 SV=1)

HSP 1 Score: 132.109 bits (331), Expect = 1.068e-32
Identity = 114/380 (30.00%), Postives = 194/380 (51.05%), Query Frame = 2 
Query:  164 DQTFKTMFDEYD--SMG-MPTQCLLKLLRRDSLGIPRQRLNRFIMRLDANKDGRVTYEEFRLFMLNIEPRDISFAKKILISLALKSCPDLINSYLPG-SCEENLMREEERHKLKNELAES-YLDAYSCYPPPVFIPIILVAQMASFVFYGLQLIHEDDPKNMLSWTTGIPR--KSPLIFDVHKRIEIWRFFSYMLIHQGYLHIIFNCXXXXXXXXXXXXVHKFWRVGPVYXXXXXXXXXXXXIIDKNSKLVGSSGGSYALIGAHFAIVIMNWDELQRDWLKIKVNFLNFVASGVVRLLFLITFLTADLGTSLYRRL---GLDITEQTSTASHIGGFVAGLLFGIPCLRNIRKKIWEVKLFWVSLSIYTGLLGFAILWNIF 1273
            +  +K +F+++D  S G + T     LL   S  +   +    +   D++ DG++ Y++F   M N   R  SF + IL      S   L+     G S  + L+R      L  E+    Y D+Y+C PPP F+  I + ++A F++ G+ L       +        PR  K+ L++    R + WR+ +Y+ +H G   +  N  +QLL+G+PLE+VH   R+G VY++GV+AGSLA S+ D  + +VGSSGG YAL+ AH A ++MNW  +       K  F       ++R+   +  ++ + G +++ R            S  +H+GG   G+  G+  LRN  +++ +  L+W+ +++YT  + FA+ WNIF
Sbjct:   36 EDHWKVLFEKFDPGSTGYISTGKFRSLLESHSSKLDPHKKEVLLALADSHADGQICYQDFVNLMSN--KRSNSFRQAILQGNRRLSSKALLEE--KGLSLSQRLIRHVAYETLPREIDRKWYYDSYTCCPPPWFMITITLLEVALFLYNGVLL-------DQFVLQVTHPRYLKNSLVYHPQLRAQAWRYVTYIFMHAGVEQLGLNVALQLLVGVPLEMVHGATRIGLVYVAGVVAGSLAVSVADMTAPVVGSSGGVYALVSAHLANIVMNWSGM-------KCQF------KLLRMAVALICMSMEFGRAVWLRFHPSAYPPCPHPSFVAHLGGVAVGITLGVVVLRNYEQRLQDQSLWWIFVTMYTIFVLFAVFWNIF 391
[Close]
BLAST of rhomboid-like protein vs. TrEMBL
Match: A0A023ZT87 (Rhomboid-like protein (Fragment) OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 465.307 bits (1196), Expect = 8.998e-161
Identity = 251/252 (99.60%), Postives = 251/252 (99.60%), Query Frame = 2 
Query:  464 MREEERHKLKNELAESYLDAYSCYPPPVFIPIILVAQMASFVFYGLQLIHEDDPKNMLSWTTGIPRKSPLIFDVHKRIEIWRFFSYMLIHQGYLHIIFNCXXXXXXXXXXXXVHKFWRVGPVYXXXXXXXXXXXXIIDKNSKLVGSSGGSYALIGAHFAIVIMNWDELQRDWLKIKVNFLNFVASGVVRLLFLITFLTADLGTSLYRRLGLDITEQTSTASHIGGFVAGLLFGIPCLRNIRKKIWEVKLFWV 1219
            MREEERHKLKNELAESYLDAYSCYPPPVFIPIILVAQMASFVFYGLQLIHEDDPKNMLSWTTGIPRKS LIFDVHKRIEIWRFFSYMLIHQGYLHIIFNCLIQLLLGIPLELVHKFWRVGPVYLSGVLAGSLASSIIDKNSKLVGSSGGSYALIGAHFAIVIMNWDELQRDWLKIKVNFLNFVASGVVRLLFLITFLTADLGTSLYRRLGLDITEQTSTASHIGGFVAGLLFGIPCLRNIRKKIWEVKLFWV
Sbjct:    1 MREEERHKLKNELAESYLDAYSCYPPPVFIPIILVAQMASFVFYGLQLIHEDDPKNMLSWTTGIPRKSSLIFDVHKRIEIWRFFSYMLIHQGYLHIIFNCLIQLLLGIPLELVHKFWRVGPVYLSGVLAGSLASSIIDKNSKLVGSSGGSYALIGAHFAIVIMNWDELQRDWLKIKVNFLNFVASGVVRLLFLITFLTADLGTSLYRRLGLDITEQTSTASHIGGFVAGLLFGIPCLRNIRKKIWEVKLFWV 252
[Close]
BLAST of rhomboid-like protein vs. TrEMBL
Match: A0A0X3NPI1 (Rhomboid-related protein 2 OS=Schistocephalus solidus OX=70667 GN=RHBL2 PE=4 SV=1)

HSP 1 Score: 308.916 bits (790), Expect = 4.545e-96
Identity = 175/443 (39.50%), Postives = 257/443 (58.01%), Query Frame = 2 
Query:  134 LSEDIYTNWLDQTFKTMFDEYDSMG-MPTQCLLKLLRRDSLGIPRQRLNRFIMRLDANKDGRVTYEEFRLFMLNIEPRDISFAKKILISLAL--------------------------------KSCPDLINSYLPGSCEEN------------LMREEERHKLKNELA------------ESYLDAYSCYPPPVFIPIILVAQMASFVFYGLQLIHE--DDPKNMLSWTTGIPRKSPLIFDVHKRIEIWRFFSYMLIHQGYLHIIFNCXXXXXXXXXXXXVHKFWRVGPVYXXXXXXXXXXXXIIDKNSKLVGSSGGSYALIGAHFAIVIMNWDELQRDWLKIKVNFLNFVASGVVRLLFLITFLTADLGTSLYRRLGLDITEQTSTASHIGGFVAGLLFGIPCLRNIRKKIWEVKLFWVSLSIYTGLLGFAILWNIFYPGY 1285
            ++E+ Y  WLD TF+ +F+ Y+S G MP + LL   + +  G+PR+R    +++LD N+DGR+ +EEFR  ++ I  +D+   K+  +   L                                +  PD ++   P S                 M++      K ++A            +SYL+AY+C PPP+FIP++++AQ+  F++Y ++L      +P N L+  +G P  SPL FD  +R E+WRFFSY L+HQG   ++FNCL  L+ G+ +E VHKFWRV PVY++GVLAGSLASS++D  + L GSSGG+YALIG H A+++MNW+ELQ D    + +FL  V+SGV RL  ++ F+  D G +LYRR GL +    S ++H+GGF+AGLL GIP LRN+ +K WE   FWVS+ I    L F I WNIF+ G+
Sbjct:   51 MTEEEYREWLDHTFRPLFEPYESQGGMPCRQLLTHFQYEDQGLPRERRIELVLKLDRNRDGRINFEEFRSILVKIRYKDLPPVKRFGLRAMLAGNPGMRLSAARSQAANHLRTIESLGRSGVFVQEVPDPVSGGFPNSQAAGGFYLEPDGIWPTSMQKGPPTTTKEQIALRKTITDEVYVPQSYLEAYNCRPPPIFIPVVVLAQICVFIYYAVELNKRAVSEPLNQLTMLSGFPYFSPLYFDPRRRREVWRFFSYFLVHQGIWQVVFNCLFTLIFGLLIEWVHKFWRVAPVYIAGVLAGSLASSVLDPFAILAGSSGGAYALIGTHLALIVMNWEELQHDITTCRYSFLGVVSSGVFRLCVILLFVGTDFGLALYRRYGLQVDVSVSISAHLGGFLAGLLVGIPVLRNLNEKPWERIFFWVSIVILVAFLIFVIFWNIFWQGF 493
[Close]
BLAST of rhomboid-like protein vs. TrEMBL
Match: A0A564YNU8 (EF-hand domain-containing protein OS=Hymenolepis diminuta OX=6216 GN=WMSIL1_LOCUS8134 PE=3 SV=1)

HSP 1 Score: 271.166 bits (692), Expect = 9.830e-83
Identity = 166/389 (42.67%), Postives = 226/389 (58.10%), Query Frame = 2 
Query:  119 MTASVLSEDIYTNWLDQTFKTMFDEYD-SMGMPTQCLLKLLRRDSLGIPRQRLNRFIMRLDANKDGRVTYEEF-RLFMLNIEP--RDISFAKKILISLALKSCPDLINSYLPGSCEENLMREEERHKLKNELAESYLDAYSCYPPPVFIPIILVAQMASFVFYGLQLIHEDDPKNMLSWTTGIPRKSPLIFDVHKRIEIWRFFSYMLIHQGYLHIIFNCXXXXXXXXXXXXVHKFWRVGPVYXXXXXXXXXXXXIIDKNSKLVGSSGGSYALIGAHFAIVIMNWDELQRDWLKIKVNFLNFVASGVVRLLFLITFLTADLGTSLYRRLGLDITEQTSTASHIGGFVAGLLFGIPCLRNIRKKIWEVKLFWVSLSIYTGLLGFAILWNIF 1273
            M A    E  +   LD  FK  F+ Y+   GMP   L +LL  DS GIP  R  RF  + D N+D RV Y+EF R  M         ++F K+ L    +   P +         + N + E + +    E   +Y++AY C PPP+FIP+I  +Q+A FV+Y + L  +D+P N ++ T+G+P KSPLI+   KR + WRF SYM IH GY H+IFNC++Q  LG  LELVHKFWRVG VY+ GVLAGSLA S+ D    L G+SGG YALIGAH A +I NW  +Q  WLK     LNF++SG VRL  ++    AD G ++Y R       +   ASH+GGF AG+L G+P LRN+  + WE   FW+ + ++   +  A+L+N F
Sbjct:    1 MGAITRGEREFREHLDVNFKPPFEAYEREGGMPLGVLQRLLH-DS-GIPPARTKRFFRKADLNRDERVNYDEFLRQIMFEDSQFLHKLAFGKRALNRAVIAVAPQMARRKQRIQMQRNGIDETDLYNWGEENVNNYIEAYDCRPPPIFIPLITFSQIAVFVYYAIVLSQDDNPFNDVTATSGVPMKSPLIYLPTKRYQAWRFVSYMFIHNGYYHLIFNCILQFALGTFLELVHKFWRVGIVYVLGVLAGSLAHSVSDPFLALAGASGGCYALIGAHVATIITNWKTMQVGWLKSP---LNFLSSGAVRLSIILLIAGADTGFAIYERFNNPNESKVGFASHLGGFAAGVLVGVPVLRNLEIERWEKVCFWICIFLFAVFMSAAVLFNGF 384
[Close]
BLAST of rhomboid-like protein vs. TrEMBL
Match: A0A267FDK2 (EF-hand domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig030849g1 PE=4 SV=1)

HSP 1 Score: 271.552 bits (693), Expect = 1.081e-82
Identity = 168/390 (43.08%), Postives = 236/390 (60.51%), Query Frame = 2 
Query:  161 LDQTFKTMFDEYDS-----MGMPTQCLLKLLRRDSLGIPRQRLNRFIMRLDANKDGRVTYEEFRLFMLNIEP---RDISFAKKILISLALKSCP-------DLINSYLPGSCEENLMREEERHKLKNELAESYLDAYSCYPPPVFIPIILVAQMASFVFYGLQLIHEDDPKNMLSW----TTGIPRKSPLIFDVHKRIEIWRFFSYMLIHQGYLHIIFNCXXXXXXXXXXXXVHKFWRVGPVYXXXXXXXXXXXXIIDKNSKLVGSSGGSYALIGAHFAIVIMNWDELQRDWLKIKVNFLNFVASGVVRLLFLITFLTADLGTSLYRRLGLDITEQTSTASHIGGFVAGLLFGIPCLRNIRKKIWEVKLFWVSLSIYTGLLGFAILWNIF 1273
            +D++F+ +F+ Y++      G+P   L + L   S  +PR R+N  + R DA+ + R+TY EF + M   +    R +   ++ +    L + P       D  +++ P   +  +              ES+ DAY C PPP+FIP+I  A++A F++Y L+      P +   W    ++G P  SPL++D  KR E WRF SYML+H GY+H+IFNCL+QL+LG+ LELVHK WRVGPVYL GV+AGSLASS  D    LVG+SGG YALIGAHFA V++NW+E+Q DWLK   N ++F  SGV RL+ L+     D G ++Y R  +D   QTS A+H GGFVAGLL G+P LRNI  K WE  +FW+ L +Y  L+   I++NIF
Sbjct:   14 IDESFRPLFERYEADPSNAEGVPMAQLSERLLESST-LPRMRINAMLRRADADANNRITYGEFVVEMTRADDDTRRRMGIGRRFINRAVLTAVPGHRPRTVDSPDTFSPWGEQAEM--------------ESFSDAYDCRPPPIFIPLITAAEIAVFLYYALE------PASRAKWPVTASSGCPMDSPLLYDPRKRWEAWRFLSYMLLHNGYIHLIFNCLVQLILGVLLELVHKLWRVGPVYLLGVVAGSLASSCFDPRIALVGASGGCYALIGAHFANVLLNWEEMQHDWLK---NPVSFFGSGVFRLIVLLLLAGGDTGLAVYNRFFIDTRSQTSFAAHGGGFVAGLLIGVPLLRNIDVKQWERVMFWIFLVLYVLLMTAGIMFNIF 379
[Close]
BLAST of rhomboid-like protein vs. TrEMBL
Match: A0A267H1J9 (EF-hand domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig030849g3 PE=4 SV=1)

HSP 1 Score: 270.011 bits (689), Expect = 5.226e-82
Identity = 168/390 (43.08%), Postives = 235/390 (60.26%), Query Frame = 2 
Query:  161 LDQTFKTMFDEYDS-----MGMPTQCLLKLLRRDSLGIPRQRLNRFIMRLDANKDGRVTYEEFRLFMLNIEP---RDISFAKKILISLALKSCP-------DLINSYLPGSCEENLMREEERHKLKNELAESYLDAYSCYPPPVFIPIILVAQMASFVFYGLQLIHEDDPKNMLSW----TTGIPRKSPLIFDVHKRIEIWRFFSYMLIHQGYLHIIFNCXXXXXXXXXXXXVHKFWRVGPVYXXXXXXXXXXXXIIDKNSKLVGSSGGSYALIGAHFAIVIMNWDELQRDWLKIKVNFLNFVASGVVRLLFLITFLTADLGTSLYRRLGLDITEQTSTASHIGGFVAGLLFGIPCLRNIRKKIWEVKLFWVSLSIYTGLLGFAILWNIF 1273
            +D++F+ +F+ Y++      G+P   L + L   S  +PR R+N  + R DA+ + R+TY EF + M   +    R +   K+ +    L + P       D  +++ P   +  +              ES+ DAY C PPP+FIP+I  A++A F++Y L+      P +   W    ++G P  SPL++   KR E WRF SYML+H GY+H+IFNCL+QL+LG+ LELVHK WRVGPVYL GV+AGSLASS  D    LVG+SGG YALIGAHFA V++NW+E+Q DWLK   N ++F  SGV RL+ L+     D G ++Y R  +D   QTS A+H GGFVAGLL G+P LRNI  K WE  +FW+ L +Y  L+   I++NIF
Sbjct:   14 IDESFRPLFERYEADPSNAEGVPMAQLSERLLESST-LPRMRINAMLRRADADANNRITYGEFVVEMTRADDDTRRRMGIGKRFINRAVLTAVPGHRPRTVDSPDTFSPWGEQAEM--------------ESFSDAYDCRPPPIFIPLITAAEIAVFLYYALE------PASRAKWPVTASSGCPMDSPLLYHPKKRWEAWRFLSYMLLHNGYIHLIFNCLVQLILGVLLELVHKLWRVGPVYLLGVVAGSLASSCFDPRIALVGASGGCYALIGAHFANVLLNWEEMQHDWLK---NPVSFFGSGVFRLIVLLLLAGGDTGLAVYNRFFIDTRSQTSFAAHGGGFVAGLLIGVPLLRNIDVKQWERVMFWIFLVLYVLLMTAGIMFNIF 379
[Close]
BLAST of rhomboid-like protein vs. Ensembl Cavefish
Match: rhbdl2 (rhomboid like 2 [Source:NCBI gene;Acc:103036677])

HSP 1 Score: 132.109 bits (331), Expect = 1.913e-34
Identity = 112/277 (40.43%), Postives = 156/277 (56.32%), Query Frame = 2 
Query:  446 SCEENLMREEERHKLKNELAESYLDAYSCYPPPVFIPIILVAQMASFVFYGLQLIHEDDPKNMLSWTTGIPRKSPLIFDVHKRIEIWRFFSYMLIHQGYLHIIFNCXXXXXXXXXXXXVHKFWRVGPVYXXXXXXXXXXXXIIDKNSKLVGSSGGSYALIGAHFAIVIMNWDELQRDWLKIKVNFLNFVASGVVRLLFLITFLTADLGTSLYRR-LGLDITEQTSTASHIGGFVAGLLFGIPCLRNIRKKIWEVKLFWVSLSIYTGLLGFAILWNIF 1273
             C +       R  L  +L E+YL+  +C PPP+FI +I + ++A F++Y +        K  ++   GI   SPL +    R E WRF SYM +H G  HI+ N ++QLLLGIPLELVHK + VG VYL GVLAGSLASSI D  S LVG+SGG YALIG +    ++N+ E+        +  L     G+ R+L ++  +  D+G +LYRR L  +   + S  +HIGG VAG+  G     N  +K+ +   FW  +  Y   L FA L+NIF
Sbjct:   42 GCCDRFHYHVSRWMLPEDLRETYLERANCLPPPIFIILISIGELAVFIYYAVW----KPQKQWVTLDQGI-WNSPLTYKPEMRQEAWRFLSYMFVHAGIQHIVGNLVLQLLLGIPLELVHKGFEVGMVYLGGVLAGSLASSIFDPYSALVGASGGVYALIGGYLMNALVNFREM--------IPLL-----GIFRILVIVIIVVTDVGFALYRRFLSTEAGLKVSFVAHIGGGVAGMTIGYVFFTNYNQKLLKDPRFWFCIVGYIVFLIFAALFNIF 300
[Close]
BLAST of rhomboid-like protein vs. Ensembl Cavefish
Match: rhbdl3 (rhomboid like 3 [Source:NCBI gene;Acc:103039963])

HSP 1 Score: 134.035 bits (336), Expect = 2.429e-34
Identity = 136/416 (32.69%), Postives = 203/416 (48.80%), Query Frame = 2 
Query:   83 MVTVLNLRSRQNMTASVLSEDI----YTNWL----DQTFKTMFDEYD---SMGMPTQCLLKLLRRDSLGIPRQRLNRFIMRLDANKDGRVTYEEFRLFMLNIEPRDISFAKKILISLALKSCPDLINSYLPGSCEENLMREEERHKLKNELAES-----YLDAYSCYPPPVFIPIILVAQMASFVFYGLQLIHEDDPKNMLSWTTGIPRKSPLIFDVHKRIEIWRFFSYMLIHQGYLHIIFNCXXXXXXXXXXXXVHKFWRVGPVYXXXXXXXXXXXXIIDKNSKLVGSSGGSYALIGAHFAIVIMNWDELQRDWLKIKVNFLNFVASGVVRLLFLITFLTADLGTSLYRRL---GLDITEQTSTASHIGGFVAGLLFGIPCLRNIRKKIWEVKLFWVSLSIYTGLLGFAILWNIF 1273
            M T  N+ S   + A+   E+I     T+ L    +  +K++FD+YD   S  + T+    LL      +   +L   +   D N DG++ Y++F   M N   R  SF + IL     +    L NS L       L +   RH     L        Y D+Y+  PPP  I  I +A+M  FV+YGLQL      + +L  ++    KSPL +    R + WR+ SY+ +H G  H+  N  +QLL+G+PLE+VH   R+G +YL GVLAGSLA S+ D  + +VGSSGG YAL+ AH A V+MNW         +K  F  F      R+   +  ++ + G +++ R            S  +H+GG V GL  G+  L+N  +++ E  LFW+   +Y   +   I WNIF
Sbjct:    1 MPTGANVHSSPAVAANAEGEEIEVLESTDVLPVAPEDQWKSLFDKYDPESSGFISTERFRDLLEAHGSELDPHKLEVLLALADGNADGKICYQDFVNLMSN--KRSNSFRRAIL-----QGSRQLKNSSLTEEVGLGLSQRLVRHVAYETLPREVDRKWYFDSYTYCPPPWLILAITIAEMVVFVYYGLQL-----DRWVLQVSSPSFLKSPLPYHPQHRAQAWRYLSYIFMHAGIEHLGLNMAMQLLVGVPLEMVHGAARIGLIYLCGVLAGSLAVSVTDMTAPVVGSSGGVYALVSAHLANVVMNWS-------GMKCQFKLF------RMAMALVCMSVEFGRAVWLRFYPPAFPPCPNPSFVAHLGGVVVGLTLGVVVLQNYEQRLQEQSLFWIFFCVYALFIFCGIFWNIF 391
[Close]
BLAST of rhomboid-like protein vs. Ensembl Cavefish
Match: rhbdl3 (rhomboid like 3 [Source:NCBI gene;Acc:103039963])

HSP 1 Score: 134.035 bits (336), Expect = 2.429e-34
Identity = 136/416 (32.69%), Postives = 203/416 (48.80%), Query Frame = 2 
Query:   83 MVTVLNLRSRQNMTASVLSEDI----YTNWL----DQTFKTMFDEYD---SMGMPTQCLLKLLRRDSLGIPRQRLNRFIMRLDANKDGRVTYEEFRLFMLNIEPRDISFAKKILISLALKSCPDLINSYLPGSCEENLMREEERHKLKNELAES-----YLDAYSCYPPPVFIPIILVAQMASFVFYGLQLIHEDDPKNMLSWTTGIPRKSPLIFDVHKRIEIWRFFSYMLIHQGYLHIIFNCXXXXXXXXXXXXVHKFWRVGPVYXXXXXXXXXXXXIIDKNSKLVGSSGGSYALIGAHFAIVIMNWDELQRDWLKIKVNFLNFVASGVVRLLFLITFLTADLGTSLYRRL---GLDITEQTSTASHIGGFVAGLLFGIPCLRNIRKKIWEVKLFWVSLSIYTGLLGFAILWNIF 1273
            M T  N+ S   + A+   E+I     T+ L    +  +K++FD+YD   S  + T+    LL      +   +L   +   D N DG++ Y++F   M N   R  SF + IL     +    L NS L       L +   RH     L        Y D+Y+  PPP  I  I +A+M  FV+YGLQL      + +L  ++    KSPL +    R + WR+ SY+ +H G  H+  N  +QLL+G+PLE+VH   R+G +YL GVLAGSLA S+ D  + +VGSSGG YAL+ AH A V+MNW         +K  F  F      R+   +  ++ + G +++ R            S  +H+GG V GL  G+  L+N  +++ E  LFW+   +Y   +   I WNIF
Sbjct:    1 MPTGANVHSSPAVAANAEGEEIEVLESTDVLPVAPEDQWKSLFDKYDPESSGFISTERFRDLLEAHGSELDPHKLEVLLALADGNADGKICYQDFVNLMSN--KRSNSFRRAIL-----QGSRQLKNSSLTEEVGLGLSQRLVRHVAYETLPREVDRKWYFDSYTYCPPPWLILAITIAEMVVFVYYGLQL-----DRWVLQVSSPSFLKSPLPYHPQHRAQAWRYLSYIFMHAGIEHLGLNMAMQLLVGVPLEMVHGAARIGLIYLCGVLAGSLAVSVTDMTAPVVGSSGGVYALVSAHLANVVMNWS-------GMKCQFKLF------RMAMALVCMSVEFGRAVWLRFYPPAFPPCPNPSFVAHLGGVVVGLTLGVVVLQNYEQRLQEQSLFWIFFCVYALFIFCGIFWNIF 391
[Close]
BLAST of rhomboid-like protein vs. Ensembl Cavefish
Match: rhbdl3 (rhomboid like 3 [Source:NCBI gene;Acc:103039963])

HSP 1 Score: 129.798 bits (325), Expect = 6.882e-33
Identity = 131/408 (32.11%), Postives = 194/408 (47.55%), Query Frame = 2 
Query:   83 MVTVLNLRSRQNMTASVLSEDIYTNWLDQTFKTMFDEYD---SMGMPTQCLLKLLRRDSLGIPRQRLNRFIMRLDANKDGRVTYEEFRLFMLNIEPRDISFAKKILISLALKSCPDLINSYLPGSCEENLMREEERHKLKNELAES-----YLDAYSCYPPPVFIPIILVAQMASFVFYGLQLIHEDDPKNMLSWTTGIPRKSPLIFDVHKRIEIWRFFSYMLIHQGYLHIIFNCXXXXXXXXXXXXVHKFWRVGPVYXXXXXXXXXXXXIIDKNSKLVGSSGGSYALIGAHFAIVIMNWDELQRDWLKIKVNFLNFVASGVVRLLFLITFLTADLGTSLYRRL---GLDITEQTSTASHIGGFVAGLLFGIPCLRNIRKKIWEVKLFWVSLSIYTGLLGFAILWNIF 1273
            M T  N+ S   + A+   E+I             ++YD   S  + T+    LL      +   +L   +   D N DG++ Y++F   M N   R  SF + IL     +    L NS L       L +   RH     L        Y D+Y+  PPP  I  I +A+M  FV+YGLQL      + +L  ++    KSPL +    R + WR+ SY+ +H G  H+  N  +QLL+G+PLE+VH   R+G +YL GVLAGSLA S+ D  + +VGSSGG YAL+ AH A V+MNW         +K  F  F      R+   +  ++ + G +++ R            S  +H+GG V GL  G+  L+N  +++ E  LFW+   +Y   +   I WNIF
Sbjct:    1 MPTGANVHSSPAVAANAEGEEIEVLESTDVLPVAPEDYDPESSGFISTERFRDLLEAHGSELDPHKLEVLLALADGNADGKICYQDFVNLMSN--KRSNSFRRAIL-----QGSRQLKNSSLTEEVGLGLSQRLVRHVAYETLPREVDRKWYFDSYTYCPPPWLILAITIAEMVVFVYYGLQL-----DRWVLQVSSPSFLKSPLPYHPQHRAQAWRYLSYIFMHAGIEHLGLNMAMQLLVGVPLEMVHGAARIGLIYLCGVLAGSLAVSVTDMTAPVVGSSGGVYALVSAHLANVVMNWS-------GMKCQFKLF------RMAMALVCMSVEFGRAVWLRFYPPAFPPCPNPSFVAHLGGVVVGLTLGVVVLQNYEQRLQEQSLFWIFFCVYALFIFCGIFWNIF 383
[Close]
BLAST of rhomboid-like protein vs. Ensembl Cavefish
Match: rhbdl3 (rhomboid like 3 [Source:NCBI gene;Acc:103039963])

HSP 1 Score: 129.413 bits (324), Expect = 1.039e-32
Identity = 127/397 (31.99%), Postives = 190/397 (47.86%), Query Frame = 2 
Query:  110 RQNMTASVLSEDIYTNW-LDQTFKTMFDEYDSMGMPTQCLLKLLRRDSLGIPRQRLNRFIMRLDANKDGRVTYEEFRLFMLNIEPRDISFAKKILISLALKSCPDLINSYLPGSCEENLMREEERHKLKNELAES-----YLDAYSCYPPPVFIPIILVAQMASFVFYGLQLIHEDDPKNMLSWTTGIPRKSPLIFDVHKRIEIWRFFSYMLIHQGYLHIIFNCXXXXXXXXXXXXVHKFWRVGPVYXXXXXXXXXXXXIIDKNSKLVGSSGGSYALIGAHFAIVIMNWDELQRDWLKIKVNFLNFVASGVVRLLFLITFLTADLGTSLYRRL---GLDITEQTSTASHIGGFVAGLLFGIPCLRNIRKKIWEVKLFWVSLSIYTGLLGFAILWNIF 1273
            R+N +     + I     L +  +  +D   S  + T+    LL      +   +L   +   D N DG++ Y++F   M N   R  SF + IL     +    L NS L       L +   RH     L        Y D+Y+  PPP  I  I +A+M  FV+YGLQL      + +L  ++    KSPL +    R + WR+ SY+ +H G  H+  N  +QLL+G+PLE+VH   R+G +YL GVLAGSLA S+ D  + +VGSSGG YAL+ AH A V+MNW         +K  F  F      R+   +  ++ + G +++ R            S  +H+GG V GL  G+  L+N  +++ E  LFW+   +Y   +   I WNIF
Sbjct:    3 RENFSMKTFGDSINARQKLAELLQKKYDPESSGFISTERFRDLLEAHGSELDPHKLEVLLALADGNADGKICYQDFVNLMSN--KRSNSFRRAIL-----QGSRQLKNSSLTEEVGLGLSQRLVRHVAYETLPREVDRKWYFDSYTYCPPPWLILAITIAEMVVFVYYGLQL-----DRWVLQVSSPSFLKSPLPYHPQHRAQAWRYLSYIFMHAGIEHLGLNMAMQLLVGVPLEMVHGAARIGLIYLCGVLAGSLAVSVTDMTAPVVGSSGGVYALVSAHLANVVMNWS-------GMKCQFKLF------RMAMALVCMSVEFGRAVWLRFYPPAFPPCPNPSFVAHLGGVVVGLTLGVVVLQNYEQRLQEQSLFWIFFCVYALFIFCGIFWNIF 374
[Close]
BLAST of rhomboid-like protein vs. Ensembl Sea Lamprey
Match: rhbdl2 (rhomboid, veinlet-like 2 (Drosophila) [Source:ZFIN;Acc:ZDB-GENE-040426-732])

HSP 1 Score: 137.117 bits (344), Expect = 4.662e-37
Identity = 106/262 (40.46%), Postives = 157/262 (59.92%), Query Frame = 2 
Query:  476 ERHKLKNELAESYLDAYSCYPPPVFIPIILVAQMASFVFYGLQLIHEDDPKNMLSWTTGIPRKSPLIFDVHKRIEIWRFFSYMLIHQGYLHIIFNCXXXXXXXXXXXXVHKFWRVGPVYXXXXXXXXXXXXIIDKNSKLVGSSGGSYALIGAHFAIVIMNWDELQRDWLKIKVNFLNFVASGVVRLLFLITFLTADLGTSLYRR-LGLDITEQTSTASHIGGFVAGLLFGIPCLRNIRKKIWEVKLFWVSLSIYTGLLGFAI 1258
             R  L  ++ E YL+  +C PPP+FI +I + ++  F++Y +        K  ++  +GI   SP I+   +R E WRF SYML+H G  HII N ++QL+LG+PLELVHK  RVG VYL+GV+AGSLASS+ D   +LVG+SGG YALIG +F  V++N+ E++  +             GV RLLF+ + + +D+G ++YRR +  +I +Q S  +HI G +AG+  G     +  + + +   FWV       LLGFAI
Sbjct:   43 SRWVLPPDIREKYLERANCLPPPIFIMLISLLELGVFIYYAVW----KPQKQWITLDSGI-SNSPFIYRPDRRQEAWRFVSYMLVHAGVQHIINNLIVQLILGLPLELVHKGHRVGLVYLAGVVAGSLASSVFDPCVQLVGASGGGYALIGGYFMNVVVNFKEMKPLF-------------GVFRLLFIGSIVLSDVGVAIYRRFIAKEIAQQVSFVAHIAGGLAGVSMGYVVFTSYDQSLVKDPRFWVC------LLGFAI 280
[Close]
BLAST of rhomboid-like protein vs. Ensembl Medaka
Match: rhbdl3 (rhomboid like 3 [Source:NCBI gene;Acc:101157837])

HSP 1 Score: 159.844 bits (403), Expect = 1.249e-43
Identity = 130/378 (34.39%), Postives = 196/378 (51.85%), Query Frame = 2 
Query:  164 DQTFKTMFDEYD---SMGMPTQCLLKLLRRDSLGIPRQRLNRFIMRLDANKDGRVTYEEFRLFMLNIEPRDISFAKKILI-SLALKSCPDLINSYLPGSCEENLMREEERHKLKNELAES-YLDAYSCYPPPVFIPIILVAQMASFVFYGLQLIHEDDPKNMLSWTTGIPRKSPLIFDVHKRIEIWRFFSYMLIHQGYLHIIFNCXXXXXXXXXXXXVHKFWRVGPVYXXXXXXXXXXXXIIDKNSKLVGSSGGSYALIGAHFAIVIMNWDELQRDWLKIKVNFLNFVASGVVRLLFLITFLTADLGTSLYRRL---GLDITEQTSTASHIGGFVAGLLFGIPCLRNIRKKIWEVKLFWVSLSIYTGLLGFAILWNIF 1273
            D  +KT+FD+YD   S  + T+    LL      +   +L   +   D N DG++ Y++F   M N   R  SF + IL  S  LK C     + L     + L+R      L  E+    Y D+Y+  PPP FI  I +A++A F++YG +L      + +L  ++    KSPL +    R + WR+FSY+ +H G  H+  N  +QLL+G+PLE+VH   R+G VYL GVLAGSLA S+ D  + +VGSSGG YAL+ AH A V+MNW         +K  F  F      R+   +  ++ + G +++ R            S  +H+GG + GL  G+  L+N  +++ E  LFW+   +YT  +  A+ WNIF
Sbjct:   47 DVQWKTLFDKYDPDNSGFISTERFKDLLETHGSELDPHKLEVLLALADGNADGKICYQDFVNLMSN--KRSNSFRRAILQGSRQLKGCSLSDEAGL--GLSQRLVRHVAYETLPREVDRKWYFDSYTYCPPPWFILAITIAEVAVFIYYGFKL-----DRLVLQVSSPSFLKSPLPYHPQLRAQAWRYFSYIFMHTGIEHLSLNMAMQLLVGVPLEMVHGALRIGLVYLCGVLAGSLAVSVTDMTAPVVGSSGGVYALVSAHLANVVMNWS-------GMKCQFKLF------RMAMALVCMSVEFGRAVWLRFYPPAFPPCPNPSFVAHLGGVLVGLTLGVVVLQNYEQRLQEQSLFWIFFCVYTLFVLCAVFWNIF 402
[Close]
BLAST of rhomboid-like protein vs. Ensembl Medaka
Match: rhbdl3 (rhomboid like 3 [Source:NCBI gene;Acc:101157837])

HSP 1 Score: 152.525 bits (384), Expect = 4.877e-41
Identity = 126/379 (33.25%), Postives = 194/379 (51.19%), Query Frame = 2 
Query:  152 TNWLDQTFKTMFDEYDSMGMPTQCLLKLLRRDSLGIPRQRLNRFIMRLDANKDGRVTYEEFRLFMLNIEPRDISFAKKILI-SLALKSCPDLINSYLPGSCEENLMREEERHKLKNELAES-YLDAYSCYPPPVFIPIILVAQMASFVFYGLQLIHEDDPKNMLSWTTGIPRKSPLIFDVHKRIEIWRFFSYMLIHQGYLHIIFNCXXXXXXXXXXXXVHKFWRVGPVYXXXXXXXXXXXXIIDKNSKLVGSSGGSYALIGAHFAIVIMNWDELQRDWLKIKVNFLNFVASGVVRLLFLITFLTADLGTSLYRRL---GLDITEQTSTASHIGGFVAGLLFGIPCLRNIRKKIWEVKLFWVSLSIYTGLLGFAILWNIF 1273
            T+ L    + ++D  +S  + T+    LL      +   +L   +   D N DG++ Y++F   M N   R  SF + IL  S  LK C     + L     + L+R      L  E+    Y D+Y+  PPP FI  I +A++A F++YG +L      + +L  ++    KSPL +    R + WR+FSY+ +H G  H+  N  +QLL+G+PLE+VH   R+G VYL GVLAGSLA S+ D  + +VGSSGG YAL+ AH A V+MNW         +K  F  F      R+   +  ++ + G +++ R            S  +H+GG + GL  G+  L+N  +++ E  LFW+   +YT  +  A+ WNIF
Sbjct:   38 TDVLPVAPEDVYDPDNSGFISTERFKDLLETHGSELDPHKLEVLLALADGNADGKICYQDFVNLMSN--KRSNSFRRAILQGSRQLKGCSLSDEAGL--GLSQRLVRHVAYETLPREVDRKWYFDSYTYCPPPWFILAITIAEVAVFIYYGFKL-----DRLVLQVSSPSFLKSPLPYHPQLRAQAWRYFSYIFMHTGIEHLSLNMAMQLLVGVPLEMVHGALRIGLVYLCGVLAGSLAVSVTDMTAPVVGSSGGVYALVSAHLANVVMNWS-------GMKCQFKLF------RMAMALVCMSVEFGRAVWLRFYPPAFPPCPNPSFVAHLGGVLVGLTLGVVVLQNYEQRLQEQSLFWIFFCVYTLFVLCAVFWNIF 394
[Close]
BLAST of rhomboid-like protein vs. Ensembl Medaka
Match: rhbdl3 (rhomboid like 3 [Source:NCBI gene;Acc:101157837])

HSP 1 Score: 150.984 bits (380), Expect = 1.483e-40
Identity = 124/368 (33.70%), Postives = 189/368 (51.36%), Query Frame = 2 
Query:  185 FDEYDSMGMPTQCLLKLLRRDSLGIPRQRLNRFIMRLDANKDGRVTYEEFRLFMLNIEPRDISFAKKILI-SLALKSCPDLINSYLPGSCEENLMREEERHKLKNELAES-YLDAYSCYPPPVFIPIILVAQMASFVFYGLQLIHEDDPKNMLSWTTGIPRKSPLIFDVHKRIEIWRFFSYMLIHQGYLHIIFNCXXXXXXXXXXXXVHKFWRVGPVYXXXXXXXXXXXXIIDKNSKLVGSSGGSYALIGAHFAIVIMNWDELQRDWLKIKVNFLNFVASGVVRLLFLITFLTADLGTSLYRRL---GLDITEQTSTASHIGGFVAGLLFGIPCLRNIRKKIWEVKLFWVSLSIYTGLLGFAILWNIF 1273
            +D  +S  + T+    LL      +   +L   +   D N DG++ Y++F   M N   R  SF + IL  S  LK C     + L     + L+R      L  E+    Y D+Y+  PPP FI  I +A++A F++YG +L      + +L  ++    KSPL +    R + WR+FSY+ +H G  H+  N  +QLL+G+PLE+VH   R+G VYL GVLAGSLA S+ D  + +VGSSGG YAL+ AH A V+MNW         +K  F  F      R+   +  ++ + G +++ R            S  +H+GG + GL  G+  L+N  +++ E  LFW+   +YT  +  A+ WNIF
Sbjct:   32 YDPDNSGFISTERFKDLLETHGSELDPHKLEVLLALADGNADGKICYQDFVNLMSN--KRSNSFRRAILQGSRQLKGCSLSDEAGL--GLSQRLVRHVAYETLPREVDRKWYFDSYTYCPPPWFILAITIAEVAVFIYYGFKL-----DRLVLQVSSPSFLKSPLPYHPQLRAQAWRYFSYIFMHTGIEHLSLNMAMQLLVGVPLEMVHGALRIGLVYLCGVLAGSLAVSVTDMTAPVVGSSGGVYALVSAHLANVVMNWS-------GMKCQFKLF------RMAMALVCMSVEFGRAVWLRFYPPAFPPCPNPSFVAHLGGVLVGLTLGVVVLQNYEQRLQEQSLFWIFFCVYTLFVLCAVFWNIF 377
[Close]
BLAST of rhomboid-like protein vs. Ensembl Medaka
Match: rhbdl2 (rhomboid like 2 [Source:NCBI gene;Acc:101175267])

HSP 1 Score: 144.05 bits (362), Expect = 5.514e-39
Identity = 107/276 (38.77%), Postives = 157/276 (56.88%), Query Frame = 2 
Query:  446 SCEENLMREEERHKLKNELAESYLDAYSCYPPPVFIPIILVAQMASFVFYGLQLIHEDDPKNMLSWTTGIPRKSPLIFDVHKRIEIWRFFSYMLIHQGYLHIIFNCXXXXXXXXXXXXVHKFWRVGPVYXXXXXXXXXXXXIIDKNSKLVGSSGGSYALIGAHFAIVIMNWDELQRDWLKIKVNFLNFVASGVVRLLFLITFLTADLGTSLYRRLGLDITEQTSTASHIGGFVAGLLFGIPCLRNIRKKIWEVKLFWVSLSIYTGLLGFAILWNIF 1273
             C E L +   ++ L  EL   YL+  +C+PPP+FI +I +A++A F++Y +        K  ++   GI   SPL +    R E WRF SYM +H G  HI+ N L+QLL+GIPLE+VHK + VG VY++GV+AGSLASSI D  S LVG+SGG YAL+G +F   I+N+ E+   +              V R++ ++  +  D G +LYRR       Q S  +H+GG  AG+  G        +K+ +   FWV ++ Y   L FA+++NIF
Sbjct:   32 GCWEKLHQSVPQYMLPKELHSVYLEKANCFPPPIFIILISIAELAVFIYYAVW----KPQKQWVTLDEGI-WNSPLTYRPDHRQEAWRFVSYMFVHAGVEHIVGNLLMQLLVGIPLEMVHKGFEVGMVYMAGVIAGSLASSIFDPFSGLVGASGGVYALLGGYFMNAIVNFREMNPIFR-------------VFRIVIIVFIVGGDFGFALYRRFVAHDNLQVSFVAHLGGIAAGMTIGFVFFSAYNQKLLKDFRFWVCIAGYIVFLFFAVVYNIF 289
[Close]
BLAST of rhomboid-like protein vs. Ensembl Medaka
Match: rhbdl2 (rhomboid like 2 [Source:NCBI gene;Acc:101175267])

HSP 1 Score: 139.813 bits (351), Expect = 1.843e-37
Identity = 109/276 (39.49%), Postives = 156/276 (56.52%), Query Frame = 2 
Query:  446 SCEENLMREEERHKLKNELAESYLDAYSCYPPPVFIPIILVAQMASFVFYGLQLIHEDDPKNMLSWTTGIPRKSPLIFDVHKRIEIWRFFSYMLIHQGYLHIIFNCXXXXXXXXXXXXVHKFWRVGPVYXXXXXXXXXXXXIIDKNSKLVGSSGGSYALIGAHFAIVIMNWDELQRDWLKIKVNFLNFVASGVVRLLFLITFLTADLGTSLYRRLGLDITEQTSTASHIGGFVAGLLFGIPCLRNIRKKIWEVKLFWVSLSIYTGLLGFAILWNIF 1273
             C E L +   ++ L  EL   YL+  +C+PPP+FI +I +A++A F++Y +        K  ++   GI   SPL +    R E WRF SYM +H G  HI+ N L+QLL+GIPLE+VHK + VG VY++GV+AGSLASSI D  S LVG+SGG YAL+G +F   I+    +Q  +  IK++FL+ V                D G +LYRR       Q S  +H+GG  AG+  G        +K+ +   FWV ++ Y   L FA+++NIF
Sbjct:   28 GCWEKLHQSVPQYMLPKELHSVYLEKANCFPPPIFIILISIAELAVFIYYAVW----KPQKQWVTLDEGI-WNSPLTYRPDHRQEAWRFVSYMFVHAGVEHIVGNLLMQLLVGIPLEMVHKGFEVGMVYMAGVIAGSLASSIFDPFSGLVGASGGVYALLGGYFMNAIVVRGCIQ--FCSIKLHFLSIVG--------------GDFGFALYRRFVAHDNLQVSFVAHLGGIAAGMTIGFVFFSAYNQKLLKDFRFWVCIAGYIVFLFFAVVYNIF 282
[Close]
BLAST of rhomboid-like protein vs. Planmine SMEST
Match: SMESG000053833.1 (SMESG000053833.1)

HSP 1 Score: 817.765 bits (2111), Expect = 0.000e+0
Identity = 423/423 (100.00%), Postives = 423/423 (100.00%), Query Frame = 2 
Query:   26 MTELGHINVSYDPDQQLRSMVTVLNLRSRQNMTASVLSEDIYTNWLDQTFKTMFDEYDSMGMPTQCLLKLLRRDSLGIPRQRLNRFIMRLDANKDGRVTYEEFRLFMLNIEPRDISFAKKILISLALKSCPDLINSYLPGSCEENLMREEERHKLKNELAESYLDAYSCYPPPVFIPIILVAQMASFVFYGLQLIHEDDPKNMLSWTTGIPRKSPLIFDVHKRIEIWRFFSYMLIHQGYLHIIFNCXXXXXXXXXXXXVHKFWRVGPVYXXXXXXXXXXXXIIDKNSKLVGSSGGSYALIGAHFAIVIMNWDELQRDWLKIKVNFLNFVASGVVRLLFLITFLTADLGTSLYRRLGLDITEQTSTASHIGGFVAGLLFGIPCLRNIRKKIWEVKLFWVSLSIYTGLLGFAILWNIFYPGYNES 1294
            MTELGHINVSYDPDQQLRSMVTVLNLRSRQNMTASVLSEDIYTNWLDQTFKTMFDEYDSMGMPTQCLLKLLRRDSLGIPRQRLNRFIMRLDANKDGRVTYEEFRLFMLNIEPRDISFAKKILISLALKSCPDLINSYLPGSCEENLMREEERHKLKNELAESYLDAYSCYPPPVFIPIILVAQMASFVFYGLQLIHEDDPKNMLSWTTGIPRKSPLIFDVHKRIEIWRFFSYMLIHQGYLHIIFNCLIQLLLGIPLELVHKFWRVGPVYLSGVLAGSLASSIIDKNSKLVGSSGGSYALIGAHFAIVIMNWDELQRDWLKIKVNFLNFVASGVVRLLFLITFLTADLGTSLYRRLGLDITEQTSTASHIGGFVAGLLFGIPCLRNIRKKIWEVKLFWVSLSIYTGLLGFAILWNIFYPGYNES
Sbjct:    1 MTELGHINVSYDPDQQLRSMVTVLNLRSRQNMTASVLSEDIYTNWLDQTFKTMFDEYDSMGMPTQCLLKLLRRDSLGIPRQRLNRFIMRLDANKDGRVTYEEFRLFMLNIEPRDISFAKKILISLALKSCPDLINSYLPGSCEENLMREEERHKLKNELAESYLDAYSCYPPPVFIPIILVAQMASFVFYGLQLIHEDDPKNMLSWTTGIPRKSPLIFDVHKRIEIWRFFSYMLIHQGYLHIIFNCLIQLLLGIPLELVHKFWRVGPVYLSGVLAGSLASSIIDKNSKLVGSSGGSYALIGAHFAIVIMNWDELQRDWLKIKVNFLNFVASGVVRLLFLITFLTADLGTSLYRRLGLDITEQTSTASHIGGFVAGLLFGIPCLRNIRKKIWEVKLFWVSLSIYTGLLGFAILWNIFYPGYNES 423
[Close]
BLAST of rhomboid-like protein vs. Planmine SMEST
Match: SMESG000001621.1 (SMESG000001621.1)

HSP 1 Score: 250.751 bits (639), Expect = 1.832e-78
Identity = 150/380 (39.47%), Postives = 227/380 (59.74%), Query Frame = 2 
Query:  161 LDQTFKTMFDEYD-SMGMPTQCLLKLLRRDSLGIPRQRLNRFIMRLDANKDGRVTYEEFRLFMLNIEPR---DISFAKKILISLALKSCPDLINSYLPGSCEENLMREEERHKLKNELAESYLDAYSCYPPPVFIPIILVAQMASFVFYGLQLIHEDDPKNMLSWTTGIPRKSPLIFDVHKRIEIWRFFSYMLIHQGYLHIIFNCXXXXXXXXXXXXVHKFWRVGPVYXXXXXXXXXXXXIIDKNSKLVGSSGGSYALIGAHFAIVIMNWDELQRDWLKIKVNFLNFVASGVVRLLFLITFLTADLGTSLYRRLGLDITEQTSTASHIGGFVAGLLFGIPCLRNIRKKIWEVKLFWVSLSIYTGLLGFAILWNIFYPGYN 1288
            ++  F+ +FD+ + + G+P   L   LR   L  P  ++NRF+   D +++  +TYEEF   +   + R    ++  K+I+ +      PD I        +     +++         ++Y +AY+C PPP  IP I ++Q+  F++Y ++L  +DD  N ++  TG+  +SPLI+  ++RIE WRF  YM +HQGY+H+IFNC++QL+LG  LE+VHKFWRV  VY+ GVLAGSLA S  D    LVG+SGG YALIGAHFA V+ NWD +Q+ WL+   N +NF++SGV RL+ L+     D G ++Y R   ++      ++HIGG +AG L GIP LRN+  K WE   FWVSL +Y   +  +I++N+     N
Sbjct:   13 IENNFRPLFDQKEVTGGIPLVELRTSLRESKL--PPNKVNRFLNNADKDQNSLITYEEFYDQLTREDSRTLEKLALRKRIIRNAVRIVAPDRI--------QRVNADQQDYCNWGEGTVKTYSEAYNCKPPPFIIPAITLSQIGVFIYYVIKLNTDDDRTNDVTARTGVHLRSPLIYSPYRRIEAWRFIGYMFLHQGYIHLIFNCIMQLVLGTLLEIVHKFWRVAIVYILGVLAGSLAHSCFDSTKYLVGASGGCYALIGAHFATVVTNWDTMQKQWLQ---NPVNFLSSGVFRLIVLLLLAGGDTGIAIYDRFSKEVPTPIGFSAHIGGALAGFLIGIPVLRNLEVKPWEKICFWVSLVLYCLFMIGSIIFNVICDSKN 379
The following BLAST results are available for this feature:
BLAST of rhomboid-like protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
RHBDL38.371e-3629.89rhomboid like 3 [Source:HGNC Symbol;Acc:HGNC:16502... [more]
RHBDL31.087e-3429.57rhomboid like 3 [Source:HGNC Symbol;Acc:HGNC:16502... [more]
RHBDL21.310e-3441.80rhomboid like 2 [Source:HGNC Symbol;Acc:HGNC:16083... [more]
RHBDL21.310e-3441.80rhomboid like 2 [Source:HGNC Symbol;Acc:HGNC:16083... [more]
RHBDL31.546e-3131.34rhomboid like 3 [Source:HGNC Symbol;Acc:HGNC:16502... [more]
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BLAST of rhomboid-like protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2
Match NameE-valueIdentityDescription
rom-14.540e-3537.83Rhomboid-related protein 1 [Source:UniProtKB/Swis... [more]
rom-24.366e-2634.56Rhomboid-related protein 2 [Source:UniProtKB/Swis... [more]
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BLAST of rhomboid-like protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rho-41.013e-4033.50gene:FBgn0030318 transcript:FBtr0073519[more]
rho-41.013e-4033.50gene:FBgn0030318 transcript:FBtr0073518[more]
stet8.943e-3731.11gene:FBgn0020248 transcript:FBtr0072712[more]
stet2.397e-3633.74gene:FBgn0020248 transcript:FBtr0072713[more]
rho4.480e-2633.20gene:FBgn0004635 transcript:FBtr0072694[more]
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BLAST of rhomboid-like protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rhbdl22.270e-3942.03rhomboid, veinlet-like 2 (Drosophila) [Source:ZFIN... [more]
rhbdl22.270e-3942.03rhomboid, veinlet-like 2 (Drosophila) [Source:ZFIN... [more]
rhbdl22.270e-3942.03rhomboid, veinlet-like 2 (Drosophila) [Source:ZFIN... [more]
rhbdl22.270e-3942.03rhomboid, veinlet-like 2 (Drosophila) [Source:ZFIN... [more]
rhbdl22.270e-3942.03rhomboid, veinlet-like 2 (Drosophila) [Source:ZFIN... [more]
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BLAST of rhomboid-like protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 1
Match NameE-valueIdentityDescription
eif4a19.751e-3837.28eukaryotic translation initiation factor 4A1 [Sour... [more]
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BLAST of rhomboid-like protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Rhbdl22.314e-3942.21rhomboid like 2 [Source:MGI Symbol;Acc:MGI:3608413... [more]
Rhbdl22.314e-3942.21rhomboid like 2 [Source:MGI Symbol;Acc:MGI:3608413... [more]
Rhbdl31.527e-3330.00rhomboid like 3 [Source:MGI Symbol;Acc:MGI:2179276... [more]
Rhbdl18.130e-2729.89rhomboid like 1 [Source:MGI Symbol;Acc:MGI:2384891... [more]
Rhbdl16.540e-2527.93rhomboid like 1 [Source:MGI Symbol;Acc:MGI:2384891... [more]
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BLAST of rhomboid-like protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|A2AGA4|RHBL2_MOUSE1.619e-3842.21Rhomboid-related protein 2 OS=Mus musculus OX=1009... [more]
sp|P58872|RHBL3_HUMAN4.020e-3529.89Rhomboid-related protein 3 OS=Homo sapiens OX=9606... [more]
sp|Q19821|RHOM1_CAEEL5.775e-3437.83Rhomboid-related protein 1 OS=Caenorhabditis elega... [more]
sp|Q9NX52|RHBL2_HUMAN6.291e-3441.80Rhomboid-related protein 2 OS=Homo sapiens OX=9606... [more]
sp|P58873|RHBL3_MOUSE1.068e-3230.00Rhomboid-related protein 3 OS=Mus musculus OX=1009... [more]
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BLAST of rhomboid-like protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A023ZT878.998e-16199.60Rhomboid-like protein (Fragment) OS=Schmidtea medi... [more]
A0A0X3NPI14.545e-9639.50Rhomboid-related protein 2 OS=Schistocephalus soli... [more]
A0A564YNU89.830e-8342.67EF-hand domain-containing protein OS=Hymenolepis d... [more]
A0A267FDK21.081e-8243.08EF-hand domain-containing protein OS=Macrostomum l... [more]
A0A267H1J95.226e-8243.08EF-hand domain-containing protein OS=Macrostomum l... [more]
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BLAST of rhomboid-like protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rhbdl21.913e-3440.43rhomboid like 2 [Source:NCBI gene;Acc:103036677][more]
rhbdl32.429e-3432.69rhomboid like 3 [Source:NCBI gene;Acc:103039963][more]
rhbdl32.429e-3432.69rhomboid like 3 [Source:NCBI gene;Acc:103039963][more]
rhbdl36.882e-3332.11rhomboid like 3 [Source:NCBI gene;Acc:103039963][more]
rhbdl31.039e-3231.99rhomboid like 3 [Source:NCBI gene;Acc:103039963][more]
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BLAST of rhomboid-like protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
rhbdl24.662e-3740.46rhomboid, veinlet-like 2 (Drosophila) [Source:ZFIN... [more]
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BLAST of rhomboid-like protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of rhomboid-like protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of rhomboid-like protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rhbdl31.249e-4334.39rhomboid like 3 [Source:NCBI gene;Acc:101157837][more]
rhbdl34.877e-4133.25rhomboid like 3 [Source:NCBI gene;Acc:101157837][more]
rhbdl31.483e-4033.70rhomboid like 3 [Source:NCBI gene;Acc:101157837][more]
rhbdl25.514e-3938.77rhomboid like 2 [Source:NCBI gene;Acc:101175267][more]
rhbdl21.843e-3739.49rhomboid like 2 [Source:NCBI gene;Acc:101175267][more]
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BLAST of rhomboid-like protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 2
Match NameE-valueIdentityDescription
SMESG000053833.10.000e+0100.00SMESG000053833.1[more]
SMESG000001621.11.832e-7839.47SMESG000001621.1[more]
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Cross References
External references for this transcript
DatabaseAccession
SmedGD GBrowseSMED30018825
GenBankAHY82405.1
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30018825 ID=SMED30018825|Name=rhomboid-like protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1494bp
GTATATTAAGTTGTATTAATTTAAAATGACTGAATTAGGGCATATTAATG
TTTCATATGATCCAGATCAACAATTAAGATCAATGGTAACAGTTCTTAAT
TTACGATCTCGACAGAATATGACTGCCAGTGTGTTATCAGAAGATATCTA
CACGAATTGGTTGGATCAAACCTTTAAAACAATGTTTGACGAATATGATT
CTATGGGGATGCCTACGCAATGTCTCCTAAAACTTTTGCGTAGAGATTCT
TTAGGAATACCAAGACAAAGACTGAATCGTTTCATTATGAGACTAGACGC
AAATAAAGATGGAAGAGTAACCTATGAAGAATTTCGATTATTTATGCTCA
ATATAGAACCACGAGATATATCTTTTGCCAAGAAGATTTTAATTTCTCTG
GCTCTCAAATCATGTCCTGATTTAATCAATTCATATCTTCCGGGGAGTTG
CGAAGAAAATCTGATGAGAGAAGAAGAACGTCATAAATTAAAAAACGAAC
TTGCTGAAAGTTATTTGGACGCTTATAGTTGTTATCCACCGCCGGTTTTC
ATTCCGATTATATTAGTAGCACAAATGGCTTCTTTCGTCTTTTATGGTTT
ACAATTAATTCATGAAGACGATCCAAAAAACATGCTTTCTTGGACAACAG
GAATCCCAAGAAAAAGTCCATTAATTTTTGATGTTCATAAACGAATAGAA
ATCTGGAGATTTTTTAGCTACATGCTTATTCATCAGGGATATTTACATAT
TATTTTCAATTGTTTGATTCAACTGTTATTGGGAATCCCATTGGAACTGG
TTCATAAATTTTGGAGAGTTGGGCCAGTTTATTTGTCAGGTGTGCTAGCC
GGTTCATTGGCAAGTTCCATTATCGATAAGAATTCCAAGCTTGTCGGTTC
AAGTGGTGGCTCGTATGCGTTGATTGGGGCCCACTTTGCTATTGTTATAA
TGAATTGGGATGAGCTACAACGTGATTGGTTGAAAATAAAAGTCAATTTT
CTTAATTTCGTCGCAAGCGGTGTCGTTCGTCTGTTGTTTTTAATTACATT
TCTGACAGCCGATCTCGGAACTTCACTTTATCGTAGGCTGGGATTAGATA
TAACTGAACAAACCAGCACTGCTTCCCATATTGGGGGATTTGTTGCAGGG
CTTCTGTTCGGAATACCTTGTTTAAGAAACATCCGGAAAAAAATATGGGA
AGTGAAATTGTTTTGGGTGTCTCTTTCCATTTACACAGGACTTTTGGGAT
TCGCAATTCTGTGGAACATATTCTATCCGGGATACAATGAGAGTTGAGTT
TCATCAAATATATTTACAGTGAAAATCTCAACCAGAAAACTTGTGAAAAT
ATTCCATTTTAAGAACTGTGATTCTTTCTATTACAGTAATGGGATTTAGA
GCGGTGAATTATTGGGTAAAATTTCTGTGGTGATGTGATTTTATTTTACC
TCAATCCAAAAGACATTTTTGTCTTCCAGCGCTGCAATTCCCAG
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protein sequence of SMED30018825-orf-1

>SMED30018825-orf-1 ID=SMED30018825-orf-1|Name=SMED30018825-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=424bp
MTELGHINVSYDPDQQLRSMVTVLNLRSRQNMTASVLSEDIYTNWLDQTF
KTMFDEYDSMGMPTQCLLKLLRRDSLGIPRQRLNRFIMRLDANKDGRVTY
EEFRLFMLNIEPRDISFAKKILISLALKSCPDLINSYLPGSCEENLMREE
ERHKLKNELAESYLDAYSCYPPPVFIPIILVAQMASFVFYGLQLIHEDDP
KNMLSWTTGIPRKSPLIFDVHKRIEIWRFFSYMLIHQGYLHIIFNCLIQL
LLGIPLELVHKFWRVGPVYLSGVLAGSLASSIIDKNSKLVGSSGGSYALI
GAHFAIVIMNWDELQRDWLKIKVNFLNFVASGVVRLLFLITFLTADLGTS
LYRRLGLDITEQTSTASHIGGFVAGLLFGIPCLRNIRKKIWEVKLFWVSL
SIYTGLLGFAILWNIFYPGYNES*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000101muscle cell
PLANA:0002075pigment cell
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR035952Rhomboid-like_sf
IPR022764Peptidase_S54_rhomboid_dom
IPR011992EF-hand-dom_pair
IPR018247EF_Hand_1_Ca_BS
IPR002048EF_hand_dom
Vocabulary: cellular component
TermDefinition
GO:0016021integral component of membrane
GO:0016020membrane
Vocabulary: molecular function
TermDefinition
GO:0004252serine-type endopeptidase activity
GO:0005509calcium ion binding
GO:0008233peptidase activity
GO:0016787hydrolase activity
Vocabulary: biological process
TermDefinition
GO:0006508proteolysis
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR022764Peptidase S54, rhomboid domainPFAMPF01694Rhomboidcoord: 222..385
e-value: 1.5E-32
score: 112.6
IPR035952Rhomboid-like superfamilyGENE3DG3DSA:1.20.1540.10coord: 173..394
e-value: 1.8E-25
score: 91.6
NoneNo IPR availableGENE3DG3DSA:1.10.238.10coord: 14..110
e-value: 1.4E-6
score: 30.4
NoneNo IPR availablePANTHERPTHR45840FAMILY NOT NAMEDcoord: 53..418
NoneNo IPR availablePANTHERPTHR45840:SF2PROTEIN RHOMBOID-RELATEDcoord: 53..418
NoneNo IPR availableSUPERFAMILYSSF144091Rhomboid-likecoord: 169..389
NoneNo IPR availableTMHMMTMhelixcoord: 262..284
NoneNo IPR availableTMHMMTMhelixcoord: 395..417
NoneNo IPR availableTMHMMTMhelixcoord: 323..345
NoneNo IPR availableTMHMMTMhelixcoord: 289..311
NoneNo IPR availableTMHMMTMhelixcoord: 233..255
NoneNo IPR availableTMHMMTMhelixcoord: 173..195
NoneNo IPR availableTMHMMTMhelixcoord: 365..383
IPR018247EF-Hand 1, calcium-binding sitePROSITEPS00018EF_HAND_1coord: 91..103
IPR002048EF-hand domainPROSITEPS50222EF_HAND_2coord: 78..113
score: 11.919
IPR011992EF-hand domain pairSUPERFAMILYSSF47473EF-handcoord: 38..111