Innexin
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30018801 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 4
Homology
BLAST of Innexin vs. Ensembl Celegans
Match: inx-13 (Innexin [Source:UniProtKB/TrEMBL;Acc:O44887]) HSP 1 Score: 120.553 bits (301), Expect = 7.159e-30 Identity = 110/386 (28.50%), Postives = 201/386 (52.07%), Query Frame = 3 Query: 213 MFFLEFLQYLKEFTFIENVGLDDSVDIINYKXXXXXXXXXXXXXXXHQYVLSPISCFVNNQIGGSNADGYLQNMCWTEGLYPMNFSRTVPTNDKGWNDISNQVLTYYQWVPMVLSLQAVVYTFPWIFWQLLNSSISGVNFTDILCKARSSHLLIKEARKRYVQSIGNQIILLIIMKEEMKR---------KYLFYSYLIIKILYIGVNCFQLVIIYYFLGFNRKDSYVKFGEKLVFDLIGGK-LPETEIFPRNGMCRHKYEQLGSINYMFLQCALPINMXXXXXXXXXXXXXXXXXXXSIYSFMDWL--IFFKINDSFQWK----LRNKIVADSTXXXXXXXXXXXXXXXIDGCFVLKMLISNSGSMIGEEIVSYIFNDFVNNYNN 1322 MFFL+ +LK + G DDS+D +NY + +LL++F +S QYV PI C++ Q G+ + Y +N C+ + Y ++ + +P ++ D + YYQWVP +L LQA+++ P +FW+L+N + SGV +L A+ + + ++AR +S G + + ++ + YL Y YL +K LY+ FQ +I+ FLG SY +G ++ D++ G+ E+ FPR MC + LG+ + +QC L INM N +Y+FL+F+++ + + + ++W + F+ K + + D++ + DKF LK DG F+ ++ +N GS+ +++ +++ F+ + +N Sbjct: 1 MFFLD--AFLKG---LHKQGDDDSIDRLNYYWTPMLLVIFALTLSAKQYVGQPIQCWIPAQFTGA-WEQYSENYCFVQNTYFISPDKYIPDSEI---DREGAEIGYYQWVPFILGLQAILFYLPSLFWRLMNFN-SGVALKKMLFGAKKADRVDEKARNEAAKSTGAHLYESLTLQSRFAKYTSAFTYGGSYLTYLYLFVKFLYLVQIVFQFIILNNFLG----TSYTFWGLGILSDILNGREWEESGHFPRVTMCDFEVRVLGNKHRHTVQCVLMINMFNEKVYVFLWFWLVIVGVATFLNLVNWTRKLMFRSARKAHIKSYLQIEDNFSDDNSRNGQILDKFVDYKLKSDGVFITHLIDNNGGSVFSHDVIVDMWDRFLQDEDN 372
BLAST of Innexin vs. Ensembl Celegans
Match: inx-1 (Innexin [Source:UniProtKB/TrEMBL;Acc:Q17394]) HSP 1 Score: 116.701 bits (291), Expect = 1.622e-28 Identity = 104/358 (29.05%), Postives = 182/358 (50.84%), Query Frame = 3 Query: 276 DDSVDIINYKXXXXXXXXXXXXXXXHQYVLSPISCFVNNQIGGSNADGYLQNMCWTEGLYPMNFSRTVPTNDKGWNDISNQVLTYYQWVPMVLSLQAVVYTFPWIFWQLLNSSISGVNFTDILCKARSSHLLIKEARKRYVQSIGNQIILLIIMKEEM---------KR--KYLFYSYLIIKILYIGVNCFQLVIIYYFLGFNRKDSYVKFGEKLVFDLIGGKLPETEI---FPRNGMCRHKYEQLGSINYMFLQCALPINMXXXXXXXXXXXXXXXXXXXSIYSFMDWLIFFKINDSFQWKLRNKIVA-DSTXXXXXXXXXXXXXXXIDGCFVLKMLISNSGSMIGEEIVSYIFNDF 1304 DD VD +NY + ++ F VS QYV PI C+V Q + + Y +N CW E Y + + P + D + ++YYQWVP VL+L+A+ + P I W+ L SG+N + A + ++ +AR VQ+I + + ++ E+ KR Y+ Y+ IK+LY+G Q+ ++ FLG + + +G ++ DL+ G+ E E+ FPR MC + LG++++ +QC L INM N I++FL+F+ + +S S W+I + +R + A D + KF +FL DG F ++M+ +++G ++ E++ ++++F Sbjct: 19 DDFVDKLNYHYTSAIIFAFAIIVSAKQYVGYPIQCWVPAQFTDA-WEQYTENYCWVENTYYLPLTSAFPLE---YGDRRARQISYYQWVPFVLALEALCFYIPCIMWRGLLHWHSGINVQSLTQMACDARMMDADARAATVQTIAGHMEDALEIQREVTDVSGMCVQKRWANYVTLLYVFIKMLYLGNVVLQVFMLNSFLGTDN----LFYGFHILRDLLNGR--EWEVSGNFPRVTMCDFEVRVLGNVHHHTVQCVLMINMFNEKIFLFLWFWYFMVAFVSAVSMFHWIIISFLPGQHMKFIRKYLRATDLATDRQSVKKFVHKFLGYDGVFCMRMISAHAGDILATELIVALWHNF 366
BLAST of Innexin vs. Ensembl Celegans
Match: inx-1 (Innexin [Source:UniProtKB/TrEMBL;Acc:Q17394]) HSP 1 Score: 116.701 bits (291), Expect = 1.622e-28 Identity = 104/358 (29.05%), Postives = 182/358 (50.84%), Query Frame = 3 Query: 276 DDSVDIINYKXXXXXXXXXXXXXXXHQYVLSPISCFVNNQIGGSNADGYLQNMCWTEGLYPMNFSRTVPTNDKGWNDISNQVLTYYQWVPMVLSLQAVVYTFPWIFWQLLNSSISGVNFTDILCKARSSHLLIKEARKRYVQSIGNQIILLIIMKEEM---------KR--KYLFYSYLIIKILYIGVNCFQLVIIYYFLGFNRKDSYVKFGEKLVFDLIGGKLPETEI---FPRNGMCRHKYEQLGSINYMFLQCALPINMXXXXXXXXXXXXXXXXXXXSIYSFMDWLIFFKINDSFQWKLRNKIVA-DSTXXXXXXXXXXXXXXXIDGCFVLKMLISNSGSMIGEEIVSYIFNDF 1304 DD VD +NY + ++ F VS QYV PI C+V Q + + Y +N CW E Y + + P + D + ++YYQWVP VL+L+A+ + P I W+ L SG+N + A + ++ +AR VQ+I + + ++ E+ KR Y+ Y+ IK+LY+G Q+ ++ FLG + + +G ++ DL+ G+ E E+ FPR MC + LG++++ +QC L INM N I++FL+F+ + +S S W+I + +R + A D + KF +FL DG F ++M+ +++G ++ E++ ++++F Sbjct: 19 DDFVDKLNYHYTSAIIFAFAIIVSAKQYVGYPIQCWVPAQFTDA-WEQYTENYCWVENTYYLPLTSAFPLE---YGDRRARQISYYQWVPFVLALEALCFYIPCIMWRGLLHWHSGINVQSLTQMACDARMMDADARAATVQTIAGHMEDALEIQREVTDVSGMCVQKRWANYVTLLYVFIKMLYLGNVVLQVFMLNSFLGTDN----LFYGFHILRDLLNGR--EWEVSGNFPRVTMCDFEVRVLGNVHHHTVQCVLMINMFNEKIFLFLWFWYFMVAFVSAVSMFHWIIISFLPGQHMKFIRKYLRATDLATDRQSVKKFVHKFLGYDGVFCMRMISAHAGDILATELIVALWHNF 366
BLAST of Innexin vs. Ensembl Celegans
Match: inx-1 (Innexin [Source:UniProtKB/TrEMBL;Acc:Q17394]) HSP 1 Score: 116.701 bits (291), Expect = 2.789e-28 Identity = 104/358 (29.05%), Postives = 182/358 (50.84%), Query Frame = 3 Query: 276 DDSVDIINYKXXXXXXXXXXXXXXXHQYVLSPISCFVNNQIGGSNADGYLQNMCWTEGLYPMNFSRTVPTNDKGWNDISNQVLTYYQWVPMVLSLQAVVYTFPWIFWQLLNSSISGVNFTDILCKARSSHLLIKEARKRYVQSIGNQIILLIIMKEEM---------KR--KYLFYSYLIIKILYIGVNCFQLVIIYYFLGFNRKDSYVKFGEKLVFDLIGGKLPETEI---FPRNGMCRHKYEQLGSINYMFLQCALPINMXXXXXXXXXXXXXXXXXXXSIYSFMDWLIFFKINDSFQWKLRNKIVA-DSTXXXXXXXXXXXXXXXIDGCFVLKMLISNSGSMIGEEIVSYIFNDF 1304 DD VD +NY + ++ F VS QYV PI C+V Q + + Y +N CW E Y + + P + D + ++YYQWVP VL+L+A+ + P I W+ L SG+N + A + ++ +AR VQ+I + + ++ E+ KR Y+ Y+ IK+LY+G Q+ ++ FLG + + +G ++ DL+ G+ E E+ FPR MC + LG++++ +QC L INM N I++FL+F+ + +S S W+I + +R + A D + KF +FL DG F ++M+ +++G ++ E++ ++++F Sbjct: 19 DDFVDKLNYHYTSAIIFAFAIIVSAKQYVGYPIQCWVPAQFTDA-WEQYTENYCWVENTYYLPLTSAFPLE---YGDRRARQISYYQWVPFVLALEALCFYIPCIMWRGLLHWHSGINVQSLTQMACDARMMDADARAATVQTIAGHMEDALEIQREVTDVSGMCVQKRWANYVTLLYVFIKMLYLGNVVLQVFMLNSFLGTDN----LFYGFHILRDLLNGR--EWEVSGNFPRVTMCDFEVRVLGNVHHHTVQCVLMINMFNEKIFLFLWFWYFMVAFVSAVSMFHWIIISFLPGQHMKFIRKYLRATDLATDRQSVKKFVHKFLGYDGVFCMRMISAHAGDILATELIVALWHNF 366
BLAST of Innexin vs. Ensembl Celegans
Match: unc-9 (Innexin unc-9 [Source:UniProtKB/Swiss-Prot;Acc:O01393]) HSP 1 Score: 106.686 bits (265), Expect = 5.350e-25 Identity = 108/368 (29.35%), Postives = 187/368 (50.82%), Query Frame = 3 Query: 276 DDSVDIINYKXXXXXXXXXXXXXXXHQYVLSPISCFVNNQIGGSNADGYLQNMCWTEGLYPMNFSRTVPTNDKGWNDISNQVLTYYQWVPMVLSLQAVVYTFPWIFWQLLNSSISGVNFTDILCKARSSHLLIKEARKRYVQSI----------------GNQIILL-IIMKEEMKRKYLFYSYLIIKILYIGVNCFQLVIIYYFLGFNRKDSYVKFGEKLVFDLIGGK-LPETEIFPRNGMCRHKYEQLGSINYMFLQCALPINMXXXXXXXXXXXXXXXXXXXSIYSFMDWLIFFKINDSFQWKLRNK----IVADSTXXXXXXXXXXXXXXXIDGCFVLKMLISNSGSMIGEEIVSYIFNDFVNN 1313 DD +D +NY + ++ +F VS QYV PI C+V + Y +N CW + Y + +P N + + N+ + YYQWVP VL+L+A+++ P I W+LL S SG++ ++ A S LL E+R R +Q+I GN++ LL +I+ + + Y+ +KILY Q+ ++ FLG NR Y G +++ DL+ G+ E+ FPR +C + + LG+++ +QC L INM N I++FL+F+ + ++ S W I+ + S Q K I + + +F FL+ DG F+L+M+ +++G + E+ ++N++ +N Sbjct: 21 DDIIDKLNYYYTTAIITVFAILVSAKQYVGFPIQCWVPATFT-EPMEQYTENYCWVQNTYFLPLHDYIPHN---YAERENRQIGYYQWVPFVLALEALLFYVPTIVWRLL-SWQSGIHVQSLVQMACDSRLLDLESRNRALQTIATNVEEALHVKHQVMSGNRLKLLNLIICTRSSGAAVTFLYISVKILYTVNIVGQIFLLNTFLG-NRSKWY---GLQVLNDLMNGREWEESGHFPRVTLCDFEVKVLGNVHRHTVQCVLMINMFNEKIFLFLWFWYFLLAGATLCSLFYW-IYISVVPSRQLNFVGKYLTGIEGYKMVDSQSLRRFVFHFLRQDGVFLLRMVATHAGELPCYELAKTLWNNYCDN 378
BLAST of Innexin vs. Ensembl Fly
Match: ogre (gene:FBgn0004646 transcript:FBtr0071037) HSP 1 Score: 50.0618 bits (118), Expect = 2.857e-6 Identity = 71/285 (24.91%), Postives = 115/285 (40.35%), Query Frame = 3 Query: 225 EFLQYLKEFTFIENVGLDDSVDIINYKXXXXXXXXXXXXXXXHQYVLSPISCFVNNQIGGSNADGYLQNMCWTEGLY--PMNFSRTVP--------TNDKGWNDISNQVLTYYQWVPMVLSLQAVVYTFPWIFWQ-----LLNSSISGVNFTDILCKARSSHLLIKEARKRYVQSIGNQIILLIIMKEEMKRKYLFYSYLIIKILYIGVNCFQLVIIYYFLGFNRKDSYVKFGEKL--VFDLIGGKL--PETEIFPRNGMCR-HKYEQLGSINYMFLQCALPINM 1019 + L LK + +++ D++V ++ + VLLL + ++ QYV PISC VN + CW + P F R V ND G D + + TYYQWV VL QA+ P W L+ + G+N T +C KEA++ +L ++K + K Y + L C +++ Y + ++ +G + + D+ + P +FPR C HKY GS+ C LP+N+ Sbjct: 3 KLLGSLKSYLKWQDIQTDNAVFRLHNSFTTVLLLTCSLIITATQYVGQPISCIVNGV-----PPHVVNTFCWIHSTFTMPDAFRRQVGREVAHPGVANDFGDED-AKKYYTYYQWVCFVLFFQAMACYTPKFLWNKFEGGLMRMIVMGLNIT--ICTREE-----KEAKR--------DALLDYLIKHVKRHKLYAIRYWACEFL----CCINIIVQMYLMNRFFDGEFLSYGTNIMKLSDVPQEQRVDPMVYVFPRVTKCTFHKYGPSGSLQKHDSLCILPLNI 262
BLAST of Innexin vs. Ensembl Fly
Match: ogre (gene:FBgn0004646 transcript:FBtr0334881) HSP 1 Score: 50.0618 bits (118), Expect = 2.857e-6 Identity = 71/285 (24.91%), Postives = 115/285 (40.35%), Query Frame = 3 Query: 225 EFLQYLKEFTFIENVGLDDSVDIINYKXXXXXXXXXXXXXXXHQYVLSPISCFVNNQIGGSNADGYLQNMCWTEGLY--PMNFSRTVP--------TNDKGWNDISNQVLTYYQWVPMVLSLQAVVYTFPWIFWQ-----LLNSSISGVNFTDILCKARSSHLLIKEARKRYVQSIGNQIILLIIMKEEMKRKYLFYSYLIIKILYIGVNCFQLVIIYYFLGFNRKDSYVKFGEKL--VFDLIGGKL--PETEIFPRNGMCR-HKYEQLGSINYMFLQCALPINM 1019 + L LK + +++ D++V ++ + VLLL + ++ QYV PISC VN + CW + P F R V ND G D + + TYYQWV VL QA+ P W L+ + G+N T +C KEA++ +L ++K + K Y + L C +++ Y + ++ +G + + D+ + P +FPR C HKY GS+ C LP+N+ Sbjct: 3 KLLGSLKSYLKWQDIQTDNAVFRLHNSFTTVLLLTCSLIITATQYVGQPISCIVNGV-----PPHVVNTFCWIHSTFTMPDAFRRQVGREVAHPGVANDFGDED-AKKYYTYYQWVCFVLFFQAMACYTPKFLWNKFEGGLMRMIVMGLNIT--ICTREE-----KEAKR--------DALLDYLIKHVKRHKLYAIRYWACEFL----CCINIIVQMYLMNRFFDGEFLSYGTNIMKLSDVPQEQRVDPMVYVFPRVTKCTFHKYGPSGSLQKHDSLCILPLNI 262
BLAST of Innexin vs. Ensembl Fly
Match: ogre (gene:FBgn0004646 transcript:FBtr0309875) HSP 1 Score: 50.0618 bits (118), Expect = 2.857e-6 Identity = 71/285 (24.91%), Postives = 115/285 (40.35%), Query Frame = 3 Query: 225 EFLQYLKEFTFIENVGLDDSVDIINYKXXXXXXXXXXXXXXXHQYVLSPISCFVNNQIGGSNADGYLQNMCWTEGLY--PMNFSRTVP--------TNDKGWNDISNQVLTYYQWVPMVLSLQAVVYTFPWIFWQ-----LLNSSISGVNFTDILCKARSSHLLIKEARKRYVQSIGNQIILLIIMKEEMKRKYLFYSYLIIKILYIGVNCFQLVIIYYFLGFNRKDSYVKFGEKL--VFDLIGGKL--PETEIFPRNGMCR-HKYEQLGSINYMFLQCALPINM 1019 + L LK + +++ D++V ++ + VLLL + ++ QYV PISC VN + CW + P F R V ND G D + + TYYQWV VL QA+ P W L+ + G+N T +C KEA++ +L ++K + K Y + L C +++ Y + ++ +G + + D+ + P +FPR C HKY GS+ C LP+N+ Sbjct: 3 KLLGSLKSYLKWQDIQTDNAVFRLHNSFTTVLLLTCSLIITATQYVGQPISCIVNGV-----PPHVVNTFCWIHSTFTMPDAFRRQVGREVAHPGVANDFGDED-AKKYYTYYQWVCFVLFFQAMACYTPKFLWNKFEGGLMRMIVMGLNIT--ICTREE-----KEAKR--------DALLDYLIKHVKRHKLYAIRYWACEFL----CCINIIVQMYLMNRFFDGEFLSYGTNIMKLSDVPQEQRVDPMVYVFPRVTKCTFHKYGPSGSLQKHDSLCILPLNI 262
BLAST of Innexin vs. Ensembl Fly
Match: ogre (gene:FBgn0004646 transcript:FBtr0071036) HSP 1 Score: 50.0618 bits (118), Expect = 2.857e-6 Identity = 71/285 (24.91%), Postives = 115/285 (40.35%), Query Frame = 3 Query: 225 EFLQYLKEFTFIENVGLDDSVDIINYKXXXXXXXXXXXXXXXHQYVLSPISCFVNNQIGGSNADGYLQNMCWTEGLY--PMNFSRTVP--------TNDKGWNDISNQVLTYYQWVPMVLSLQAVVYTFPWIFWQ-----LLNSSISGVNFTDILCKARSSHLLIKEARKRYVQSIGNQIILLIIMKEEMKRKYLFYSYLIIKILYIGVNCFQLVIIYYFLGFNRKDSYVKFGEKL--VFDLIGGKL--PETEIFPRNGMCR-HKYEQLGSINYMFLQCALPINM 1019 + L LK + +++ D++V ++ + VLLL + ++ QYV PISC VN + CW + P F R V ND G D + + TYYQWV VL QA+ P W L+ + G+N T +C KEA++ +L ++K + K Y + L C +++ Y + ++ +G + + D+ + P +FPR C HKY GS+ C LP+N+ Sbjct: 3 KLLGSLKSYLKWQDIQTDNAVFRLHNSFTTVLLLTCSLIITATQYVGQPISCIVNGV-----PPHVVNTFCWIHSTFTMPDAFRRQVGREVAHPGVANDFGDED-AKKYYTYYQWVCFVLFFQAMACYTPKFLWNKFEGGLMRMIVMGLNIT--ICTREE-----KEAKR--------DALLDYLIKHVKRHKLYAIRYWACEFL----CCINIIVQMYLMNRFFDGEFLSYGTNIMKLSDVPQEQRVDPMVYVFPRVTKCTFHKYGPSGSLQKHDSLCILPLNI 262
BLAST of Innexin vs. Ensembl Fly
Match: ogre (gene:FBgn0004646 transcript:FBtr0309873) HSP 1 Score: 50.0618 bits (118), Expect = 2.857e-6 Identity = 71/285 (24.91%), Postives = 115/285 (40.35%), Query Frame = 3 Query: 225 EFLQYLKEFTFIENVGLDDSVDIINYKXXXXXXXXXXXXXXXHQYVLSPISCFVNNQIGGSNADGYLQNMCWTEGLY--PMNFSRTVP--------TNDKGWNDISNQVLTYYQWVPMVLSLQAVVYTFPWIFWQ-----LLNSSISGVNFTDILCKARSSHLLIKEARKRYVQSIGNQIILLIIMKEEMKRKYLFYSYLIIKILYIGVNCFQLVIIYYFLGFNRKDSYVKFGEKL--VFDLIGGKL--PETEIFPRNGMCR-HKYEQLGSINYMFLQCALPINM 1019 + L LK + +++ D++V ++ + VLLL + ++ QYV PISC VN + CW + P F R V ND G D + + TYYQWV VL QA+ P W L+ + G+N T +C KEA++ +L ++K + K Y + L C +++ Y + ++ +G + + D+ + P +FPR C HKY GS+ C LP+N+ Sbjct: 3 KLLGSLKSYLKWQDIQTDNAVFRLHNSFTTVLLLTCSLIITATQYVGQPISCIVNGV-----PPHVVNTFCWIHSTFTMPDAFRRQVGREVAHPGVANDFGDED-AKKYYTYYQWVCFVLFFQAMACYTPKFLWNKFEGGLMRMIVMGLNIT--ICTREE-----KEAKR--------DALLDYLIKHVKRHKLYAIRYWACEFL----CCINIIVQMYLMNRFFDGEFLSYGTNIMKLSDVPQEQRVDPMVYVFPRVTKCTFHKYGPSGSLQKHDSLCILPLNI 262
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|O01393|UNC9_CAEEL (Innexin unc-9 OS=Caenorhabditis elegans OX=6239 GN=unc-9 PE=1 SV=1) HSP 1 Score: 106.686 bits (265), Expect = 6.805e-24 Identity = 108/368 (29.35%), Postives = 187/368 (50.82%), Query Frame = 3 Query: 276 DDSVDIINYKXXXXXXXXXXXXXXXHQYVLSPISCFVNNQIGGSNADGYLQNMCWTEGLYPMNFSRTVPTNDKGWNDISNQVLTYYQWVPMVLSLQAVVYTFPWIFWQLLNSSISGVNFTDILCKARSSHLLIKEARKRYVQSI----------------GNQIILL-IIMKEEMKRKYLFYSYLIIKILYIGVNCFQLVIIYYFLGFNRKDSYVKFGEKLVFDLIGGK-LPETEIFPRNGMCRHKYEQLGSINYMFLQCALPINMXXXXXXXXXXXXXXXXXXXSIYSFMDWLIFFKINDSFQWKLRNK----IVADSTXXXXXXXXXXXXXXXIDGCFVLKMLISNSGSMIGEEIVSYIFNDFVNN 1313 DD +D +NY + ++ +F VS QYV PI C+V + Y +N CW + Y + +P N + + N+ + YYQWVP VL+L+A+++ P I W+LL S SG++ ++ A S LL E+R R +Q+I GN++ LL +I+ + + Y+ +KILY Q+ ++ FLG NR Y G +++ DL+ G+ E+ FPR +C + + LG+++ +QC L INM N I++FL+F+ + ++ S W I+ + S Q K I + + +F FL+ DG F+L+M+ +++G + E+ ++N++ +N Sbjct: 21 DDIIDKLNYYYTTAIITVFAILVSAKQYVGFPIQCWVPATFT-EPMEQYTENYCWVQNTYFLPLHDYIPHN---YAERENRQIGYYQWVPFVLALEALLFYVPTIVWRLL-SWQSGIHVQSLVQMACDSRLLDLESRNRALQTIATNVEEALHVKHQVMSGNRLKLLNLIICTRSSGAAVTFLYISVKILYTVNIVGQIFLLNTFLG-NRSKWY---GLQVLNDLMNGREWEESGHFPRVTLCDFEVKVLGNVHRHTVQCVLMINMFNEKIFLFLWFWYFLLAGATLCSLFYW-IYISVVPSRQLNFVGKYLTGIEGYKMVDSQSLRRFVFHFLRQDGVFLLRMVATHAGELPCYELAKTLWNNYCDN 378
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|Q23157|INX11_CAEEL (Innexin-11 OS=Caenorhabditis elegans OX=6239 GN=inx-11 PE=3 SV=1) HSP 1 Score: 101.679 bits (252), Expect = 8.059e-22 Identity = 105/381 (27.56%), Postives = 186/381 (48.82%), Query Frame = 3 Query: 276 DDSVDIINYKXXXXXXXXXXXXXXXHQYVLSPISCFVNNQIGGSNADGYLQNMCWTEGLYPMNFSRTVPTNDKGWNDISNQVLTYYQWVPMVLSLQAVVYTFPWIFWQLLNSSISGVNFTDILCKARSSHLLIKEARKRYVQSIGNQIILLIIMKEEMKRK------------------YLFYSYLIIKILYIGVNCF-QLVIIYYFLGFNRKDSYVKFGEKLVFDLIGGKLPE-TEIFPRNGMCRHKYEQLGSINYMFLQCALPINMXXXXXXXXXXXXXXXXXXXSIYSFMDWLIFFKINDSFQWKLRNKIV---------ADSTXXXXXXXXXXXXXXXIDGCFVLKMLISNSGSMIGEEIVSYIFNDF-VNNYNNDI 1328 DD D +NY ++ +LL F+ +S Q+ PI C N+ GS + Y +N CW++ Y + ++ V K ++ L+YYQWVP L LQA + P W+ S+ SG+ +++ KA+ S + +E R++ + + + + + M+RK ++ + YL K+LY +N F QL ++ YFLG NR Y G +V D++ G+ E + FPR +C + Q+ +I +QC L IN+ N I++ L+F+ + +L S S + W I +W ++ + +S +D KF ++L DG FVL+M+ S++G + ++V ++ + + N D+ Sbjct: 20 DDWSDRLNYLMTPNILLAFSVLISFKQFGGRPIECMFPNKFPGS-WEQYAENYCWSQDTYFVEPTQDVSLLKKEERYTPDRQLSYYQWVPFFLLLQAAFFRAPSYLWKYF-SNHSGIRIHEVVEKAKDSANVEEEVREKNILILKRHLSSALRFQANMERKKVQVHKTVTFLNFQYSSGFISWIYLFTKVLYF-LNVFAQLYLMNYFLGTNRHHWY---GFGVVQDIVQGEPWERSGYFPRAAVCDFEVRQVANIQRYSVQCVLVINIFNEKIFVLLWFWYVILLLSSTVSLVQWFIVLVFPCFSKWFVKQHLALSTLQNFNQRNSRREDSDVSKFVTQYLHKDGVFVLRMVSSHAGIIFATDLVQALYEAYDFQDKNKDV 394
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|Q03412|UNC7_CAEEL (Innexin unc-7 OS=Caenorhabditis elegans OX=6239 GN=unc-7 PE=1 SV=1) HSP 1 Score: 94.7449 bits (234), Expect = 1.623e-19 Identity = 103/377 (27.32%), Postives = 183/377 (48.54%), Query Frame = 3 Query: 276 DDSVDIINYKXXXXXXXXXXXXXXXHQYVLSPISCFVNNQIGGSNADGYLQNMCWTEGLYPMNFSRTVPTNDKGWNDISNQVLTYYQWVPMVLSLQAVVYTFPWIFWQLLNSSISGVNFTDILCKARSSHLLIKEARKRYVQSIG----NQIILLIIMKEEMKRK-----------------YLFYSYLIIKILYIGVNCFQLVIIYYFLGFNRKDSYVKFGEKLVFDLIGG-KLPETEIFPRNGMCRHKYEQLGSINYMFLQCALPINMXXXXXXXXXXXXXXXXXXXSIYSFMDWLIFFKIND---SFQWK-LR------NKIVADSTXXXXXXXXXXXXXXXIDGCFVLKMLISNSGSMIGEEIVSYIFNDFVN 1310 DD VD +NY + +L F VS QYV PI C+V + + Y +N CW + Y + +P + N+ + YYQWVP +L+++A+++ P I W+ L SG+N ++ A + L+ E + R V ++ +++ L I ++ R Y+ Y+ IK+LY Q ++ + LG N + +G L+ DL+ + +T +FPR +C + LG+I+ +QC L INM N I++FL+F+ + +++ + M W++ I SF K LR K +AD K+ + F ++ DG F+L+M+ +++G ++ E++ ++ DF N Sbjct: 139 DDFVDKLNYYYTTTILASFALLVSAKQYVGFPIQCWVPATFTDA-MEQYTENYCWVQNTYWVPMQEDIP---REIYSRRNRQIGYYQWVPFILAIEALLFYVPCILWRGLLYWHSGINLQGLVQMACDARLMDSEIKTRTVYTMARHMQDEVQLTNIDRQGHSRSCFSNLQLGANCGRHCGCYVTMLYIGIKVLYSANVLLQFFLLNHLLGSND----LAYGFSLLKDLMHAIEWEQTGMFPRVTLCDFEVRVLGNIHRHTVQCVLMINMFNEKIFLFLWFWFLTCGIVTVCNTMYWILIMFIPSQGMSFVRKYLRVLPDHPAKPIADDVTLRKFTNNFLRK----DGVFMLRMISTHAGELMSSELILALWQDFNN 503
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|O61787|INX16_CAEEL (Innexin-16 OS=Caenorhabditis elegans OX=6239 GN=inx-16 PE=3 SV=2) HSP 1 Score: 92.8189 bits (229), Expect = 2.571e-19 Identity = 95/352 (26.99%), Postives = 171/352 (48.58%), Query Frame = 3 Query: 276 DDSVDIINYKXXXXXXXXXXXXXXXHQYVLSPISCFVNNQIGGSNADGYLQNMCWTEGLY--PMNFSRTVPTNDKGWNDISNQVLTYYQWVPMVLSLQAVVYTFPWIFWQLLNSSISGVNFTDILCKARSSHLLIKEARKRYVQSIGNQIILLIIMKEEMKRKY---LFYSYLIIKILYIGVNCFQLVIIYYFLGFNRKDSYVKFGEKLVFDLIGGK-LPETEIFPRNGMCRHKYEQLGSINYMFLQCALPINMXXXXXXXXXXXXXXXXXXXSIYSFMDWLIFFKINDS-----FQWKLRNKIVADSTXXXXXXXXXXXXXXXIDGCFVLKMLISNSGSMIGEEIVSYIFN 1298 D S+D +NY V+ +L+ F+ + YV P+ C+ NQ G + + ++ C+ E Y PM S + + + YYQWVP +L +QA+ + P FW ++ S SG+ D++ AR + ++ A + Q + +I + E ++ + +F YL++K+L + +V+ ++ L +Y +G + +D++ G+ E+ FPR C +LG+I++ LQC L +NM N I+IFL+F+ +L + F+ W+ ++ DS F L N+ D + + DG L++L SNSG + EE++ I+N Sbjct: 22 DTSIDRLNYVVTTSILIAFSLLLFAKNYVGEPMQCWTPNQFAGG-WESFAESYCFIENTYFVPMQDSNLPAAETR-----EGREMIYYQWVPFLLVIQALFFCVPRAFW-IIYPSYSGLTIADMITAARQNGKQLEGADEALEQ------VAMINWRTEQQKGHGSRIFNCYLVMKLLIL----LNIVLQFFLLNSFLNTAYTFWGWGIFWDMVNGRHWQESGHFPRVSFCDINVRELGNIHHWSLQCVLMVNMFNEKIFIFLWFWFAFLLVATAGDFVIWV--WRRFDSNSKLGFILDLLNQEGIDHSPQKASELYKNVLRD--DGVLFLRLLDSNSGRLNSEELMKKIYN 352
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|O61715|INX19_CAEEL (Innexin-19 OS=Caenorhabditis elegans OX=6239 GN=inx-19 PE=1 SV=2) HSP 1 Score: 89.3521 bits (220), Expect = 7.760e-18 Identity = 105/410 (25.61%), Postives = 196/410 (47.80%), Query Frame = 3 Query: 195 FFHCTLMFFLEFLQYLKEFTFIENVGLDDSVDIINYKXXXXXXXXXXXXXXXHQYVLSPISCFVNNQIGGSNADGYLQNMCWTEGLYPMNFSRTVPTNDKGWNDISNQVLTYYQWVPMVLSLQAVVYTFPWIFWQLLNSSISGVNFTDILCKARSSHLLIKEA-RKRYVQSIGNQIILLIIMKEEMKR--------KYLFYSYLIIKILYIGVNCFQLV----IIYYFLGFN---RKDSYVKFGEKLVFDLIGGK-LPETEIFPRNGMCRHKYEQLGSINYMFLQCALPINMXXXXXXXXXXXXXXXXXXXSIYSFMDWLI--------------FFKINDSFQWKLRNKIVADSTXXXXXXXXXXXXX---------XXIDGCFVLKMLISNSGSMIGEEIVSYIFNDF 1304 FFH TL F+ L G DD+VD +NY + ++L + +S QY +PI C+VN + + Y+++ CW + Y + VP + + + + YYQWVP +L +A++++ P IFW+L S SG+N ++ A L+ + R++ V++I + + ++ R + F +L + L I + +L+ ++ FL N + ++ FG +++ D+ G+ ET FPR +C + L ++N +QCAL IN+IN ++ FL+ + + + I+ SF+ W+ F +I +S ++K K D+T++ Y + LK DG +L+M+ +++G MI ++V ++ +F Sbjct: 18 FFHATLA--RSFINALSV------RGDDDAVDRLNYYYTPLILAVCCLVISAKQYGGTPIECWVNPH-SRESMEEYIESYCWIQNTYWIPMYENVPDDHTAREE---KQIGYYQWVPFILIAEALMFSLPCIFWRLC-SFQSGLNIQTLINAACDGQALLDASDRQKAVEAITTNFVDNLDLQSPNGRIRARGWIARIKFSRFLSGQCLSILHSFTKLLYSMNVVAQFLILNACLKSSDFLFFGFQVLNDIWAGRPWTETGHFPRVTLCDFEVRYLANLNRYTVQCALLINIINEKVFAFLWCWYMILAIITTCSFIYWIANSFIHSEKVDYVMKFIQIAESSEFKKLQKFEKDATVERLYTVIAFAPHLLDTFVSDFLKSDGVLMLRMISNHAGDMIVVQLVRNLWQEF 414
BLAST of Innexin vs. TrEMBL
Match: T1E108 (Innexin OS=Dendrocoelum lacteum OX=27895 GN=inx PE=2 SV=1) HSP 1 Score: 355.91 bits (912), Expect = 3.937e-116 Identity = 205/366 (56.01%), Postives = 273/366 (74.59%), Query Frame = 3 Query: 213 MFFLEFLQYLKEFTFIENVGLDDSVDIINYKXXXXXXXXXXXXXXXHQYVLSPISCFVNNQIGGSNADGYLQNMCWTEGLYPMNFSRTVPTNDKGWNDISNQVLTYYQWVPMVLSLQAVVYTFPWIFWQLLNSSISGVNFTDILCKARSSHLLIKEARKRYVQSIGNQIILLIIMKEEMKRKYLFYSYLIIKILYIGVNCFQLVIIYYFLGFNRKDSYVKFGEKLVFDLIGGKL-PETEIFPRNGMCRHKYEQLGSINYMFLQCALPINMXXXXXXXXXXXXXXXXXXXSIYSFMDWLIFFKINDSFQWKLRNKIVADSTXXXXXXXXXXXXXXXIDGCFVLKMLISNSGSMIGEEIVSYIFNDFV 1307 MFFL+FLQ+LKEF+ I+NVGLDD+ D INY+ +V++LL+F +FV++ QY SPISCFV ++IGG N D YLQNMCWTEGLYP+NFSRT+P N+K W+D+SNQ L YY WVPMVL LQA++Y FPW+ WQ + ISGVNF DI+ +RS+HLLI + R++ V++I N + L+ +K ++ LF++YL IK+ YI NC QL +IYY L F RK+ Y +FGE++ DL+ G+ ET IFPR+GMCR K+E LG++NYMF QC+LPINMIN IY+FLYFYIIC + ++ YS W+I F F LRN+I+ +S K YF++F FLKIDG FVLKM+ SN GS++ EEI++ IF +V Sbjct: 1 MFFLQFLQHLKEFSVIDNVGLDDTFDRINYQGNVIVLLIFMTFVTVRQYFYSPISCFVISRIGGRNQDKYLQNMCWTEGLYPVNFSRTIPQNNKDWDDLSNQQLEYYAWVPMVLGLQAIMYLFPWLLWQFTSFWISGVNFVDIMRISRSAHLLIDDVRRKQVKNIANGLFALMKLKTWLRTNLLFFTYLFIKLCYIITNCIQLWLIYYLLTFGRKEGYFRFGERIFSDLVNGRTWSETLIFPRSGMCRFKFENLGAVNYMFAQCSLPINMINEKIYVFLYFYIICNIILTTYSLCLWIIGFGFCKMFIHTLRNRILENSKKKTLYFEEFVNGFLKIDGTFVLKMVNSNVGSLMSEEIINGIFERYV 366
BLAST of Innexin vs. TrEMBL
Match: A0A183KAE8 (Innexin OS=Schistosoma curassoni OX=6186 GN=inx PE=3 SV=1) HSP 1 Score: 197.978 bits (502), Expect = 2.677e-53 Identity = 144/400 (36.00%), Postives = 221/400 (55.25%), Query Frame = 3 Query: 225 EFLQYLKEFTFIENVGLDDSVDIINYKXXXXXXXXXXXXXXXHQYVLSPISCFVNNQIGGSNADGYLQNMCWTEGLYPMNF-SRTVPTNDKGWNDISNQVLTYYQWVPMVLSLQAVVYTFPWIFWQLLNSSISGVNFTDILCKARSSHLLIK---EARKRYVQSIGNQIILLIIMKEEMK------------------RKY---LFYSYLIIKILYIGVNCFQLVIIYYFLGFNRKDSYVKFGEKLVFDLIGGKL-PETEIFPRNGMCRHKYEQLGSINYMFLQCALPINMXXXXXXXXXXXXXXXXXXXSIYSFMDWLI--------------FFKINDSFQWKLRNKIVADSTXXXXXXXXXXXXXXXIDGCFVLKMLISNSGSMIGEEIVSYIFNDF 1304 EFL Y++ F+ VG +D D N++ +V++LLL V++ QY ++P+ C++ + G NAD Y+ N+CW EG +P+N S VP + W+ + Q + YYQWVP+VL LQA++Y P I W + + +G + +++ R ++L+ K E R++ VQ I + LL+ + E + +++ L Y YL IKILY + FQL ++Y+FL FN + Y FG +L+ D+I GK ET+IFPR GMCRH + +G+ N +F QC LPINM+N IYIFL+F++ I+ ++I S WL F KI D + + D+F EFL+ DG F+L+ML N+G +I EIV +F D+ Sbjct: 5 EFLGYIQSFSVCNFVGFEDLADRANFQWNVIVLLLCMVLVTMRQYFMTPLVCYLPTTVSGVNADSYITNLCWIEGTFPINLTSGIVPHKLQEWDALRPQQMNYYQWVPLVLGLQAILYYIPRIIWSIFTYNRTGTDLQNLI---RQANLITKEDGEKRQKMVQHIAKTLELLLFNRREYRTMDTLNHSFRRSLSFMPGKRHGNNLIYVYLTIKILYSIIGFFQLYLMYFFLRFNSYEGYWLFGYRLLTDIINGKQWTETQIFPRVGMCRHTLQHVGASNTLFAQCVLPINMLNEKIYIFLFFFLGSIMLLTILSIPLWLYRMGLKQRQRHFIKRFLKIADVYD--------RNDPKMALLTDRFMNEFLRKDGHFILRMLSMNAGDLITVEIVCNLFADY 393
BLAST of Innexin vs. TrEMBL
Match: A0A0R3WKF9 (Innexin OS=Hydatigena taeniaeformis OX=6205 GN=inx PE=3 SV=1) HSP 1 Score: 197.208 bits (500), Expect = 3.053e-53 Identity = 135/396 (34.09%), Postives = 222/396 (56.06%), Query Frame = 3 Query: 213 MFFLEFLQYLKEFTFIENVGLDDSVDIINYKXXXXXXXXXXXXXXXHQYVLSPISCFVNNQIGGSNADGYLQNMCWTEGLYPMNFSR-TVPTNDKGWNDISNQVLTYYQWVPMVLSLQAVVYTFPWIFWQLLNSSISGVNFTDILCKARSSHLLIKEARKRYVQSIGNQIILLIIMKEEMKRKY-------------------LFYSYLIIKILYIGVNCFQLVIIYYFLGFNRKDSYVKFGEKLVFDLIGGKL-PETEIFPRNGMCRHKYEQLGSINYMFLQCALPINMXXXXXXXXXXXXXXXXXXXSIYSFMDWLIFFKINDSFQ-------WKLRNKIVADSTXXXXXXXXXXXXXXXIDGCFVLKMLISNSGSMIGEEIVSYIFNDFVNNY 1316 M EFL Y++ F+ VG++D D N++ +V++LL+ V++ QY ++P+ C++ + G NA+ Y+ N+CW EG +P+N + VPT+ K W+ + ++ YYQWVP+VL LQA++Y P I W + + +G + ++ A S+ E R++ V+ + + LL+ + E + L Y Y+ IKILY+ + QL ++Y FL F+RK+ Y+ FG KL+ D+ G+L ET++FPR G CRH + + + N +F QC LPINM+N IYIFLYF++ ++ ++ S WL F+I+ Q K+ + D + D+F EFL+ DG F+L+ML N+G +I EIV +F ++ + Sbjct: 1 MVATEFLGYIQSFSATTYVGVEDLADRANFQWNVIVLLISMVLVTVRQYFMAPLVCYLPTTVSGGNAESYVTNLCWVEGTFPINLTTGVVPTDVKAWSSTNPGIMNYYQWVPLVLGLQAIIYYVPRIIWSIFTYNRTGTDLQSLIRTADSAAKDEGEKREKAVRHMAKSLELLLFNRREYHHRSGGPLARVLRGLPGKRHGNNLIYYYIFIKILYVCIGISQLYLMYTFLRFDRKEGYLFFGWKLLDDIRRGRLWTETQVFPRVGACRHTLQHVAAGNNLFAQCVLPINMLNEKIYIFLYFFLAGVMLFTVISIPLWL--FRISKYRQRHFVKRFLKMADVYNRDDSQLKDLIDRFINEFLRQDGHFLLRMLSMNAGDLITVEIVCCLFGNYRKQF 394
BLAST of Innexin vs. TrEMBL
Match: A0A183LII3 (Innexin OS=Schistosoma margrebowiei OX=48269 GN=inx PE=3 SV=1) HSP 1 Score: 196.823 bits (499), Expect = 9.025e-53 Identity = 144/404 (35.64%), Postives = 219/404 (54.21%), Query Frame = 3 Query: 213 MFFLEFLQYLKEFTFIENVGLDDSVDIINYKXXXXXXXXXXXXXXXHQYVLSPISCFVNNQIGGSNADGYLQNMCWTEGLYPMNF-SRTVPTNDKGWNDISNQVLTYYQWVPMVLSLQAVVYTFPWIFWQLLNSSISGVNFTDILCKARSSHLLIK---EARKRYVQSIGNQIILLIIMKEEMKR---------------------KYLFYSYLIIKILYIGVNCFQLVIIYYFLGFNRKDSYVKFGEKLVFDLIGGKL-PETEIFPRNGMCRHKYEQLGSINYMFLQCALPINMXXXXXXXXXXXXXXXXXXXSIYSFMDWLI--------------FFKINDSFQWKLRNKIVADSTXXXXXXXXXXXXXXXIDGCFVLKMLISNSGSMIGEEIVSYIFNDF 1304 M EF+ Y++ F+ VG +D D N++ +V++LLL V++ QY ++P+ C++ + G NAD Y+ N+CW EG +P+N S VP + W+ + Q + YYQWVP+VL LQA++Y P I W + + +G + +++ R ++L+ K E R++ VQ I + LL+ + E + L Y YL IKILY + FQL ++Y+FL FN + Y FG +L+ D+I GK ET+IFPR GMCRH + +G+ N +F QC LPINM+N IYIFL+F++ I+ ++I S WL F KI D + + D+F EFL+ DG F+L+ML N+G +I EIV +F D+ Sbjct: 1 MVASEFIGYIQSFSVCNFVGFEDLADRANFQWNVIVLLLCMVLVTMRQYFMTPLVCYLPTTVSGVNADSYITNLCWIEGTFPINLTSGIVPHKLQEWDALRPQQMNYYQWVPLVLGLQAILYYIPRIIWSIFTYNRTGTDLQNLI---RQANLITKEDGEKRQKMVQHIAKTLELLLFNRREYRTMDTLSSSFRRSLSFMPGKRHGNNLIYVYLTIKILYSIIGFFQLYLMYFFLRFNSYEGYWLFGYRLLTDIINGKQWTETQIFPRVGMCRHTLQHVGASNTLFAQCVLPINMLNEKIYIFLFFFLGSIMLLTILSIPLWLYRMGLKQRQRHFIKRFLKIADVYD--------RNDPKMALLTDRFMNEFLRKDGHFILRMLSMNAGDLITVEIVCNLFADY 393
BLAST of Innexin vs. TrEMBL
Match: A0A5J4NGN9 (Innexin OS=Paragonimus westermani OX=34504 GN=inx PE=3 SV=1) HSP 1 Score: 195.667 bits (496), Expect = 1.508e-52 Identity = 136/397 (34.26%), Postives = 221/397 (55.67%), Query Frame = 3 Query: 213 MFFLEFLQYLKEFTFIENVGLDDSVDIINYKXXXXXXXXXXXXXXXHQYVLSPISCFVNNQIGGSNADGYLQNMCWTEGLYPMNF-SRTVPTNDKGWNDISNQVLTYYQWVPMVLSLQAVVYTFPWIFWQLLNSSISGVNFTDILCKARSSHLLIKEARKRYVQSIGNQIILLIIMKEEMK------------------RKY---LFYSYLIIKILYIGVNCFQLVIIYYFLGFNRKDSYVKFGEKLVFDLIGGKL-PETEIFPRNGMCRHKYEQLGSINYMFLQCALPINMXXXXXXXXXXXXXXXXXXXSIYSFMDWLIFFKINDSFQWKLRN--KIV----ADSTXXXXXXXXXXXXXXXIDGCFVLKMLISNSGSMIGEEIVSYIFNDFVNNY 1316 M EFL Y++ F+ VG +D D N++ +V++LL+ V+L QY ++P+ C++ + G NAD Y+ N+CW EG +P+N S VP W+ + Q + YYQWVP+VL LQA++Y P IFW + + +G + +++ + S E R++ VQ I + LL+ + E + +++ L Y YL +KILY + QL ++Y FL F+ ++ Y+ FG +++ D++ GK ET++FPR GMCRH + +G+ N +F QC LPINM+N IY+FLYF++ ++ I++ S W++ + + +R KI D D+F EFL+ DG F+L+M+ N+G +I EIV +F D+ Y Sbjct: 1 MVAAEFLGYVQSFSACNYVGFEDLADRANFQWNVIVLLICMVLVTLRQYFMTPLVCYLPTTVSGVNADSYITNLCWIEGTFPINLTSGVVPHRMTEWDALKPQQMNYYQWVPLVLGLQAILYYLPRIFWSIFTYNRTGTDLQNLVRTSNSITKEEGEKRQKMVQHIARTLELLLFNRREYRGGSGSISDRLRHSSVIPGKRHGNNLVYVYLFVKILYALIGACQLYLMYIFLRFDAREGYLFFGFRVLKDIVDGKPWTETQVFPRVGMCRHTLQHVGASNRLFAQCVLPINMLNEKIYVFLYFFLGAVMCITLISIPMWVLRMGMKRHQRHFVRRFLKIADVYDRDDPKMSLLVDRFIAEFLRQDGHFILRMISMNAGDLITVEIVCCLFADYKKQY 397
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000042154.1 (SMESG000042154.1) HSP 1 Score: 635.565 bits (1638), Expect = 0.000e+0 Identity = 370/375 (98.67%), Postives = 372/375 (99.20%), Query Frame = 3 Query: 213 MFFLEFLQYLKEFTFIENVGLDDSVDIINYKXXXXXXXXXXXXXXXHQYVLSPISCFVNNQIGGSNADGYLQNMCWTEGLYPMNFSRTVPTNDKGWNDISNQVLTYYQWVPMVLSLQAVVYTFPWIFWQLLNSSISGVNFTDILCKARSSHLLIKEARKRYVQSIGNQIILLIIMKEEMKRKYLFYSYLIIKILYIGVNCFQLVIIYYFLGFNRKDSYVKFGEKLVFDLIGGKLPETEIFPRNGMCRHKYEQLGSINYMFLQCALPINMXXXXXXXXXXXXXXXXXXXSIYSFMDWLIFFKINDSFQWKLRNKIVADSTXXXXXXXXXXXXXXXIDGCFVLKMLISNSGSMIGEEIVSYIFNDFVNNYNNDILTT 1337 MFFLEFLQYLKEFTFIENVGLDDSVDIINYKVSVVLLLLFTSFVSLHQYVLSPISCFVNNQIGGSNADGYLQNMCWTEGLYPMNFSRTVPTNDKGWNDISNQVLTYYQWVPMVLSLQAVVYTFPWIFWQLLNSSISGVNFTDILCKARSSHLLIKEARKRYVQSIGNQIILLIIMKE+MKRKYL YSYLIIKILYIGVNCFQLVIIYYFLGFNRKDSYVKFGEKLVFDLIGGKL ETEIFPRNGMCRHKYEQLGSINYMFLQCALPINMINVNIYIFLYFYIICILTISIYSFMDWLIFFKINDSFQWKLRNKIVADSTLKDKYFDKFYKEFLKIDGCFVLKMLISNSGSMIGEEIV+YIFNDFVNNYNN ILTT Sbjct: 1 MFFLEFLQYLKEFTFIENVGLDDSVDIINYKVSVVLLLLFTSFVSLHQYVLSPISCFVNNQIGGSNADGYLQNMCWTEGLYPMNFSRTVPTNDKGWNDISNQVLTYYQWVPMVLSLQAVVYTFPWIFWQLLNSSISGVNFTDILCKARSSHLLIKEARKRYVQSIGNQIILLIIMKEKMKRKYLIYSYLIIKILYIGVNCFQLVIIYYFLGFNRKDSYVKFGEKLVFDLIGGKLHETEIFPRNGMCRHKYEQLGSINYMFLQCALPINMINVNIYIFLYFYIICILTISIYSFMDWLIFFKINDSFQWKLRNKIVADSTLKDKYFDKFYKEFLKIDGCFVLKMLISNSGSMIGEEIVNYIFNDFVNNYNNYILTT 375
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000043575.1 (SMESG000043575.1) HSP 1 Score: 190.274 bits (482), Expect = 5.774e-55 Identity = 104/289 (35.99%), Postives = 167/289 (57.79%), Query Frame = 3 Query: 213 MFFLEFLQYLKEFTFIENVGLDDSVDIINYKXXXXXXXXXXXXXXXHQYVLSPISCFVNNQIGGSNADGYLQNMCWTEGLYPMNFSRTVPTNDKGWNDISNQVLTYYQWVPMVLSLQAVVYTFPWIFWQLLNSSISGVNFTDILCKARSSHLLIKEARKRYVQSIGNQIILLI-------IMKEEMKRK------------YLFYSYLIIKILYIGVNCFQLVIIYYFLGFNRKDSYVKFGEKLVFDLIGGK-LPETEIFPRNGMCRHKYEQLGSINYMFLQCALPINM 1019 M E L Y+ F+ + GL+D D N++ ++++LL+ VS+ QY ++PI C++++ GGSNA+ Y+ NMCW EG P+NFS VP + W + + YYQW+P VLSLQAV+Y P +FWQ++ + G++ ++ A ++ E R++ ++ I I +++ +KE + + L Y +IKI YI V QL+I+++FL NRK+ Y FG +++ +++ GK ET++FPR GMCR+ EQ+G+ N QC LPINM Sbjct: 1 MIASELLSYVNGFSVAQYAGLEDFSDRANFQGNIIVLLICMLIVSMRQYFMNPIICYISSVPGGSNAEDYITNMCWVEGTVPLNFSAKVPHKLEDWKLLQQDRMNYYQWIPFVLSLQAVLYYLPKLFWQIITYNRIGMDLEQLVKDANDANSEDDETRRKIIEHISRNIEIMLYGHRKIKTLKETVGNRIFRHVPGKRNGNLLVSYYFLIKIAYISVGFIQLLIMFHFLKLNRKEGYQLFGHRILRNILSGKDWTETQVFPRVGMCRNALEQMGNTNNAVAQCLLPINM 289
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000030970.1 (SMESG000030970.1) HSP 1 Score: 155.221 bits (391), Expect = 3.998e-42 Identity = 129/396 (32.58%), Postives = 201/396 (50.76%), Query Frame = 3 Query: 231 LQYLKEFTFIENVGLDDSVDIINYKXXXXXXXXXXXXXXXHQYVLSPISCFVNNQIGGSNADGYLQNMCWTEGLYPMNFSRTVPTNDKGWNDISNQVLTYYQWVPMVLSLQAVVYTFPWIFWQLLNSSISGVNFTDILCKARSSHLLIKEARKRYVQSIGNQIILLI----------IMKEEMKRKY------------LFYSYLIIKILYIGVNCFQLVIIYYFLGFNRKDSYVKFGEKLVFDLIGGK-LPETEIFPRNGMCRHKYEQLGSINYMFLQCALPINMXXXXXXXXXXXXXXXXXXXSIYSFMDWLIFFKI--NDSFQWKLRNKIVADSTXXXXXXXXXXXXXXXI----DGCFVLKMLISNSGSMIGEEIVSYIFNDFVNNYNNDIL 1331 +Q + F +N G++D D ++ K S ++ L S + QY + PISC+ GGSN Y+++ C+ G+ P++F+ T+PT +K W I YYQWVP L QAV+ P I W+ + +F I+ +A + L E RK V + + ++ +++ E R + L YL+IKILY+ Q+ ++ FL N D Y FG K++ D+I GK ++IFPR G C K+ LG+ NY+ QCALP+NM+N +YIFL+F+++ + ISI S WLI I N + + K+ D T ++ K +F KI DG F L++L +N G +I E+VS ++ + Y N L Sbjct: 6 IQLVSRFKLFQNGGMEDFSDRLSSKFSCLIFLTLGSVILFKQYWIRPISCYFAVDPGGSNLIQYIESYCYVHGIIPISFNGTMPTKEKDWIAIDKTRTLYYQWVPFALYGQAVMCYIPHIIWRFFRKRQNNADFNHIIQRANRAIELDDEKRKNEVIHLAQALKNILFQNRTCDSTSVLRREANRIHSKIIEWIKMGIPLVIYYLVIKILYVTNAVGQIYLMKSFLRLNSSD-YKFFGSKILNDIIHGKNWQVSKIFPRVGFCLGKFRHLGATNYVTAQCALPLNMLNEKVYIFLWFWMLILSVISITSLFMWLIRMLISRNKTDFLNMYLKLSGDYTHRELKDKKKIVKFEKIFLRNDGMFFLRILATNVGDLITAEVVSQLWKIYAPCYENTEL 400
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000065083.1 (SMESG000065083.1) HSP 1 Score: 155.221 bits (391), Expect = 5.666e-42 Identity = 124/396 (31.31%), Postives = 209/396 (52.78%), Query Frame = 3 Query: 225 EFLQYLKEFTFIENVGLDDSVDIINYKXXXXXXXXXXXXXXXHQYVLSPISCFVNNQIGGSNADGYLQNMCWTEGLYPMNFSRTVPTNDKGWNDISNQVLTYYQWVPMVLSLQAVVYTFPWIFWQLLNSSISGVNFTDILCKARSSHLLIKEARKRYVQSIGNQIILLIIMKEE--------MKRK----------------YLFYSYLIIKILYIGVNCFQLVIIYYFLGFNRKDSYVKFGEKLVFDLIGGK-LPETEIFPRNGMCRHKYEQLGSINYMFLQCALPINMXXXXXXXXXXXXXXXXXXXSIYSFMDWL-----IFFKINDSFQWKLRNKIVADSTXXXXXXXXXXXXXXXIDGCFVLKMLISNSGSMIGEEIVSYIFNDFVNNYNN 1322 EFL YL + NVGL+D D +N+ SV++L++ V++ QYV PISC++ N IGGSN Y++N+CW +G ++ P+ D+ W ++ + YYQWVP +L LQ +++ P + WQ++ + +G + ++ A + EAR + V + + L+ + +RK +L SYL++K+ Y+ QL+I+ FLGF+ + + FG ++ ++ G T IFPR C K LG IN M QC LP+NM+N IY FL+ +I+ +L+++I S W+ I ++ + Q+ + ++ + ++ KF +FL+ DG F+LKM+ N+G +I EIV ++N + NY N Sbjct: 5 EFLDYLSKLQVSTNVGLEDLPDRLNFTFSVIVLMVCILIVTVKQYVFKPISCYLPNNIGGSNLLSYVENLCWVQGTIALSNQAKFPSTDEEWKNLEKHKMLYYQWVPFMLGLQCIMFYVPKLVWQIICYNRTGTDIQHLVVSANQAVHSSDEARSKMVSYLSKTLEQLLYQHRDHRSGKLAKFRRKIHNSVGFLMCSKRIGTWLVSSYLLLKLSYVANGFIQLIIMQKFLGFSDFN-LLTFGIEVGNNIWSGTDWKTTLIFPRVSYCFVKVTHLGVINSMVAQCVLPVNMLNERIYFFLWCWILIVLSLTILSIPIWILRILCIKYRRHFIRQFLIISEEITKDQKENYLLAKFESQFLRHDGIFLLKMISLNAGDIITSEIVCQLWNIYKTNYVN 399
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000030964.1 (SMESG000030964.1) HSP 1 Score: 154.451 bits (389), Expect = 1.378e-41 Identity = 117/398 (29.40%), Postives = 201/398 (50.50%), Query Frame = 3 Query: 237 YLKEFTFIENVGLDDSVDIINYKXXXXXXXXXXXXXXXHQYVLSPISCFVNNQIGGSNADGYLQNMCWTEGLYPMNFSRTVPTNDKGWNDISNQVLTYYQWVPMVLSLQAVVYTFPWIFWQLLNSSISGVNFTDILCKARSSHLLIKEARKRYVQSIGNQI-ILLIIMKEE----------MKRK-------------YLFYSYLIIKILYIGVNCFQLVIIYYFLGFNRKDSYVKFGEKLVFDLIGGKLPETEIFPRNGMCRHKYEQLGSINYMFLQCALPINMXXXXXXXXXXXXXXXXXXXSIYSFMDWLI--------------FFKINDSFQWKLRNKIVADSTXXXXXXXXXXXXXXXIDGCFVLKMLISNSGSMIGEEIVSYIFNDFVNNY 1316 + + F G DD D +++K S + ++ +S +HQY+ PISC+V+ + GG + Y++N CW EG P+NFS T P N+K W + + YYQW+P +L LQA+ P + W+LL + +G N +++ KA+ + + +E+R + V+ + + +L ++++ + RK YL Y IKILY+ QL +I L + D+++ FG KL+ + G+ + IFP+ G C + +G +N++ QCALP N+IN ++IFL+F++I + I+ S + W+ + KI D Q+K K + K G F+L+M+ +NSG +I +IV+ ++N F Y Sbjct: 8 HRQNFDLFTTDGFDDFSDRLSFKYSCFIFMVASSLSMVHQYMFIPISCYVSTESGGKHLIDYIENYCWVEGTIPINFSMTFPRNEKEWASAEKEKILYYQWIPFILQLQAISCFIPHLLWKLLYINNNGQNIDNLVSKAKKAVVKDEESRLKEVRHLAKVLEAMLFEIRDDNSANSSFGRNLCRKIYEFCILGKRLGAYLIVFYFFIKILYLLNAISQLFLIQLLLSPHSSDNHLLFGVKLLSNAFNGETKQESIFPKFGFCFVQLRHVGGVNFVVSQCALPANVINEKMFIFLWFWMIIVSIITSISILVWIFESYLQYNKTAFLKKYLKIKDLNQYKDVQKNLLKKFEKRFLKS---------SGLFILRMIATNSGDLITADIVNQLWNIFKEKY 396 The following BLAST results are available for this feature:
BLAST of Innexin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 0
BLAST of Innexin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Innexin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Innexin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 0
BLAST of Innexin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 0
BLAST of Innexin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 0
BLAST of Innexin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Innexin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Innexin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 0
BLAST of Innexin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 0
BLAST of Innexin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Innexin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 0
BLAST of Innexin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 0
BLAST of Innexin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30018801 ID=SMED30018801|Name=Innexin|organism=Schmidtea mediterranea sexual|type=transcript|length=1439bpback to top protein sequence of SMED30018801-orf-1 >SMED30018801-orf-1 ID=SMED30018801-orf-1|Name=SMED30018801-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=376bp MFFLEFLQYLKEFTFIENVGLDDSVDIINYKVSVVLLLLFTSFVSLHQYVback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
|