Programmed cell death 11
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30018697 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 8
Homology
BLAST of Programmed cell death 11 vs. Ensembl Human
Match: PDCD11 (programmed cell death 11 [Source:HGNC Symbol;Acc:HGNC:13408]) HSP 1 Score: 216.853 bits (551), Expect = 5.862e-56 Identity = 192/739 (25.98%), Postives = 339/739 (45.87%), Query Frame = 3
Query: 66 LLGRIKEIHEFKLIISLPHNKSGVCRIANISEEYNKLINEFNEDKSIMNEVARLNQLFSKGQIVQVKLTK----NSSNKKNELSMIPSEINCNINANRLKQGIKLQVAIKSREDKGYILETGIGGINSFLPFTECS--------NAEYKTGKMLEVFPVITPEKKSRVTNFTTDIQKRNLVHSSFDPCDFDVILPGMLIKTYLKLSIDGSLEGKFHGFPVCVQPIHHKITDQISTELT-----MCVIGIDLSLKQLDCSLLSHLKPPFKGSTDLL---------DVCIGYSEKNCTVTKRDKTKIVI-----SIPDKKYVTGFIAKGHIDPKLQKTDIGSNVIVRYLDYNLIDNVIHATTLNSLLAQSYFSIHQAKLGEIIKGKVLSFSKHGFTVKISSNLTGLIPIPHLSDKPMSNAQKLLAPGDQVQCRVFHIDLLENRLLLTIKKSLMTSTLPIISGISDLQTGMILCGFVAKIFDFGLVVIMFNNVKGWVP-----IGRVPESKRKSLRVAYYVGKPVEVKVIRWEVATNKIELSLKEESTIDEEVIEKNPVND-------LEIGDIYEAVITKARVDGFNVRLCPSNKVAFLPFIHLSDSREHRKLFEAHYRMSEKDQLKXXXXXXXXXXXXXXXSKKKSLIEAAVKNEVVKSNNSLTINSQWIGWVIKNESFGLLVELPSGVKGLVRNKDISDILPLSGQSRDLFEIGDTVMAKIIELDPLNLNRILFTLKMS 2153
+LG +KE++E +L+ISLP+ G ++ I + Y K +NE + + ++ L +LFS G +V+ ++ + K +LS+ P +N ++A LK G+ L + S ED GY+++ G+ G +FLP + A+ K G+ L V+ + + + + + +LPG+++K ++ L F F V H + T + C++ + + + SL P + T L DV + K T R K ++ + D K V +P+ K G+ R +DY+ +D + + S++ Y H + G ++KG VL+ +G VK+ + GL+P HL+D M N +K GD+V+CRV D +L++T+KK+L+ S LP+I+ +D + G+ GF+ ++ D+G +V +NNV+G VP +P+ +R +Y G+ V+V V+ E + ++ LS K S D E +K P + IG + + + + DG V + P N AFLP HLSD + L H+ + D L V+ ++ V++ +K +L+ + K+ + + IG+V + +G+ ++ PSG+ GL +SD S + D F G TV AK+ +D R+L +L++S
Sbjct: 86 ILGCVKEVNELELVISLPNGLQGFVQVTEICDAYTKKLNEQVTQEQPLKDLLHLPELFSPGMLVRCVVSSLGITDRGKKSVKLSLNPKNVNRVLSAEALKPGMLLTGTVSSLEDHGYLVDIGVDGTRAFLPLLKAQEYIRQKNKGAKLKVGQYLNCIVEKVKGNGGVVSLSVGHSEVSTAIATEQQSWNLNNLLPGLVVKAQVQKVTPFGLTLNFLTFFTGVVDFMHLDPKKAGTYFSNQAVRACILCVHPRTRVVHLSLRPIFLQPGRPLTRLSCQNLGAVLDDVPVQGFFKKAGATFRLKDGVLAYARLSHLSDSKNV--------FNPEAFKP--GNTHKCRIIDYSQMDELALLSLRTSIIEAQYLRYHDIEPGAVVKGTVLTIKSYGMLVKVGEQMRGLVPPMHLADILMKNPEKKYHIGDEVKCRVLLCDPEAKKLMMTLKKTLIESKLPVITCYADAKPGLQTHGFIIRVKDYGCIVKFYNNVQGLVPKHELSTEYIPDPER-----VFYTGQVVKVVVLNCEPSKERMLLSFKLSS--DPEP-KKEPAGHSQKKGKAINIGQLVDVKVLEKTKDGLEVAVLPHNIRAFLPTSHLSDHVANGPLL--HHWLQAGDILH-RVLCLSQSEGRVLLCRKPALVSTVEGGQDPKNFSEIHPGMLLIGFVKSIKDYGVFIQFPSGLSGLAPKAIMSDKFVTS--TSDHFVEGQTVAAKVTNVDE-EKQRMLLSLRLS 800 HSP 2 Score: 67.781 bits (164), Expect = 2.052e-10 Identity = 48/208 (23.08%), Postives = 98/208 (47.12%), Query Frame = 3
Query: 3756 KNPTTETEFELLIFNHPHDSNAWIKFMNFYLENDKNIDKARSIAERAMKMLLSNDIENRFQLMKKYMLLEIDELVAKKDDVSYDDQLIRFRELCQRAMT-QKAKQMYIHVCKNLINAKLFDLAEELSKRFIKDFPNDSVSW--FHLFLIRFSQKKYLVVRETLVNAQRSLSVADFRDLTIRVAQAEIEQGDVSRGVQSLVDIFQNRPK 4370
+ P + +F+ L+ + P+ S W+++M F+L+ + I+KAR++AERA+K + + + + + LL ++ + ++ ++ ++ +RA+ + ++++H+ ++ F A EL R +K F + W + FL+R SQ L A L + D+ + AQ E + GD R + PK
Sbjct: 1600 RQPESADDFDRLVLSSPNSSILWLQYMAFHLQATE-IEKARAVAERALKTISFREEQEKLNVW--VALLNLENMYGSQESLT---------KVFERAVQYNEPLKVFLHLADIYAKSEKFQEAGELYNRMLKRFRQEKAVWIKYGAFLLRRSQAA--ASHRVLQRALECLPSKEHVDVIAKFAQLEFQLGDAERAKAIFENTLSTYPK 1793
BLAST of Programmed cell death 11 vs. Ensembl Human
Match: PDCD11 (programmed cell death 11 [Source:HGNC Symbol;Acc:HGNC:13408]) HSP 1 Score: 216.853 bits (551), Expect = 6.226e-56 Identity = 192/739 (25.98%), Postives = 339/739 (45.87%), Query Frame = 3
Query: 66 LLGRIKEIHEFKLIISLPHNKSGVCRIANISEEYNKLINEFNEDKSIMNEVARLNQLFSKGQIVQVKLTK----NSSNKKNELSMIPSEINCNINANRLKQGIKLQVAIKSREDKGYILETGIGGINSFLPFTECS--------NAEYKTGKMLEVFPVITPEKKSRVTNFTTDIQKRNLVHSSFDPCDFDVILPGMLIKTYLKLSIDGSLEGKFHGFPVCVQPIHHKITDQISTELT-----MCVIGIDLSLKQLDCSLLSHLKPPFKGSTDLL---------DVCIGYSEKNCTVTKRDKTKIVI-----SIPDKKYVTGFIAKGHIDPKLQKTDIGSNVIVRYLDYNLIDNVIHATTLNSLLAQSYFSIHQAKLGEIIKGKVLSFSKHGFTVKISSNLTGLIPIPHLSDKPMSNAQKLLAPGDQVQCRVFHIDLLENRLLLTIKKSLMTSTLPIISGISDLQTGMILCGFVAKIFDFGLVVIMFNNVKGWVP-----IGRVPESKRKSLRVAYYVGKPVEVKVIRWEVATNKIELSLKEESTIDEEVIEKNPVND-------LEIGDIYEAVITKARVDGFNVRLCPSNKVAFLPFIHLSDSREHRKLFEAHYRMSEKDQLKXXXXXXXXXXXXXXXSKKKSLIEAAVKNEVVKSNNSLTINSQWIGWVIKNESFGLLVELPSGVKGLVRNKDISDILPLSGQSRDLFEIGDTVMAKIIELDPLNLNRILFTLKMS 2153
+LG +KE++E +L+ISLP+ G ++ I + Y K +NE + + ++ L +LFS G +V+ ++ + K +LS+ P +N ++A LK G+ L + S ED GY+++ G+ G +FLP + A+ K G+ L V+ + + + + + +LPG+++K ++ L F F V H + T + C++ + + + SL P + T L DV + K T R K ++ + D K V +P+ K G+ R +DY+ +D + + S++ Y H + G ++KG VL+ +G VK+ + GL+P HL+D M N +K GD+V+CRV D +L++T+KK+L+ S LP+I+ +D + G+ GF+ ++ D+G +V +NNV+G VP +P+ +R +Y G+ V+V V+ E + ++ LS K S D E +K P + IG + + + + DG V + P N AFLP HLSD + L H+ + D L V+ ++ V++ +K +L+ + K+ + + IG+V + +G+ ++ PSG+ GL +SD S + D F G TV AK+ +D R+L +L++S
Sbjct: 86 ILGCVKEVNELELVISLPNGLQGFVQVTEICDAYTKKLNEQVTQEQPLKDLLHLPELFSPGMLVRCVVSSLGITDRGKKSVKLSLNPKNVNRVLSAEALKPGMLLTGTVSSLEDHGYLVDIGVDGTRAFLPLLKAQEYIRQKNKGAKLKVGQYLNCIVEKVKGNGGVVSLSVGHSEVSTAIATEQQSWNLNNLLPGLVVKAQVQKVTPFGLTLNFLTFFTGVVDFMHLDPKKAGTYFSNQAVRACILCVHPRTRVVHLSLRPIFLQPGRPLTRLSCQNLGAVLDDVPVQGFFKKAGATFRLKDGVLAYARLSHLSDSKNV--------FNPEAFKP--GNTHKCRIIDYSQMDELALLSLRTSIIEAQYLRYHDIEPGAVVKGTVLTIKSYGMLVKVGEQMRGLVPPMHLADILMKNPEKKYHIGDEVKCRVLLCDPEAKKLMMTLKKTLIESKLPVITCYADAKPGLQTHGFIIRVKDYGCIVKFYNNVQGLVPKHELSTEYIPDPER-----VFYTGQVVKVVVLNCEPSKERMLLSFKLSS--DPEP-KKEPAGHSQKKGKAINIGQLVDVKVLEKTKDGLEVAVLPHNIRAFLPTSHLSDHVANGPLL--HHWLQAGDILH-RVLCLSQSEGRVLLCRKPALVSTVEGGQDPKNFSEIHPGMLLIGFVKSIKDYGVFIQFPSGLSGLAPKAIMSDKFVTS--TSDHFVEGQTVAAKVTNVDE-EKQRMLLSLRLS 800 HSP 2 Score: 67.781 bits (164), Expect = 2.069e-10 Identity = 48/208 (23.08%), Postives = 98/208 (47.12%), Query Frame = 3
Query: 3756 KNPTTETEFELLIFNHPHDSNAWIKFMNFYLENDKNIDKARSIAERAMKMLLSNDIENRFQLMKKYMLLEIDELVAKKDDVSYDDQLIRFRELCQRAMT-QKAKQMYIHVCKNLINAKLFDLAEELSKRFIKDFPNDSVSW--FHLFLIRFSQKKYLVVRETLVNAQRSLSVADFRDLTIRVAQAEIEQGDVSRGVQSLVDIFQNRPK 4370
+ P + +F+ L+ + P+ S W+++M F+L+ + I+KAR++AERA+K + + + + + LL ++ + ++ ++ ++ +RA+ + ++++H+ ++ F A EL R +K F + W + FL+R SQ L A L + D+ + AQ E + GD R + PK
Sbjct: 1601 RQPESADDFDRLVLSSPNSSILWLQYMAFHLQATE-IEKARAVAERALKTISFREEQEKLNVW--VALLNLENMYGSQESLT---------KVFERAVQYNEPLKVFLHLADIYAKSEKFQEAGELYNRMLKRFRQEKAVWIKYGAFLLRRSQAA--ASHRVLQRALECLPSKEHVDVIAKFAQLEFQLGDAERAKAIFENTLSTYPK 1794
BLAST of Programmed cell death 11 vs. Ensembl Celegans
Match: let-716 (pep chromosome:WBcel235:III:6383552:6389401:1 gene:WBGene00002850.1 transcript:C16A3.3.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:let-716) HSP 1 Score: 100.138 bits (248), Expect = 1.073e-20 Identity = 107/458 (23.36%), Postives = 208/458 (45.41%), Query Frame = 3
Query: 156 SEEYNKLINEFNEDKSIMNEVARLNQLFSKGQIVQVK-LTKNSSNKKNELSMI--PSEINCNINANRLKQGIKLQVAIKSREDKGYILETGIGGINSFLPFTECSNAEYKTGKMLEVFPVITPEKKSRVTNFTTDIQKRNLVHSSFDPCDFDVILPGMLIK---------TYLKLSIDGSLEGKF--HGFPVCVQPIHHKITDQISTELTMCVIGIDLSLKQLDCSLLSHLKPPFKGSTDLLDVCIGYSEKNCTVTKRDKTK--IVISIP----DKKYVTGFIAKGHIDPKLQ---KTDIGSNVIVRYLDYNLIDNVIHATTLNSLLAQSYFSIHQAKLGEIIKGKVLSFSKHGFTVKISSNLTGLIPIPHLSDKPMSNAQKL---LAPGDQVQCRVFHIDLLENRLLLTIKKSLMTSTLPIISGISDLQTGMILCGFVAKIFDFGLVVI-MFNNVKG 1448
SE K FNE+K + F GQ+V + ++K N K ++ P+ +N +++ N L G+ L A+ S E+KG IL+ G+ I F+ ++ A K G L + V++ SRV T+ +++ NL +S + + ++PG +++ + ++I L+G P ++ K+ I + C + + +++ + + T + IG K CTV TK + ++P K VT ++G ++ Q + ++G+ + R + D I +T +L Q AK G+++ +V +K G + + + P+ LSDKP+ AQK+ G +V+CRV+ I L++T ++S++ P ++ + +L+ G+ + + K+F G++++ FNN+ G
Sbjct: 102 SEVSKKFTELFNEEK------IEIKNAFQLGQMVPFRVISKKQGNDKGKVKGTCNPARLNKHLSPNMLAAGLVLHTAVVSIEEKGAILDVGLDQITGFIEKSQFPAAGLKEGMPL-IVRVLS--STSRVVKVTSFVEQDNLNMTSCEKLQLNHLMPGTILECEPTGDAVTAGVIVNIGNGLKGILPRRNLPPRLRENPEKLGKAIRAIVMFCQQNSKILVLNAHPDIVAASR--IEKRTSFEGISIGDKVK-CTVIDVLPTKSMVYFALPAIDGKKSLVTAVSSRGLLEKPDQVSTEYEVGTEKLCRVTGFRYADRSITISTRKDILNQKITKYQDAKCGDVLDARVHHVAKSGVYFMVCNFVKAFAPLSMLSDKPLP-AQKMKNIYKVGTEVKCRVWQICDERKNLIVTCRESILGLKSPSVNSVQELEIGVTVPCVIRKVFPTGVLLLGTFNNICG 546
BLAST of Programmed cell death 11 vs. Ensembl Fly
Match: CG5728 (gene:FBgn0039182 transcript:FBtr0084632) HSP 1 Score: 63.1586 bits (152), Expect = 2.501e-9 Identity = 58/223 (26.01%), Postives = 108/223 (48.43%), Query Frame = 3
Query: 33 LN*LIMENDSILLGRIKEIHEFKLIISLPHNKSGVCRIANISEEYNKLINE-FNEDKSIMNEVARLNQLFSKGQIVQVKLTKNSSNKKNELSMI----PSEINCNINANRLKQGIKLQVAIKSREDKGYILETGIGGINSFLPFTECSNAEYK--TGKM--LEVFPVITPEKKSRVTNFTTDIQKRNLVHSSFDPCDFDVILPGMLIK----TYLKLSIDGSL 662
LN ++ D +++G +KE+ L I+LP +A+IS+ Y ++ + D S E L +LF G+IV K K +S++ P++++ N++ +K+G A+ + GY++E+G+ G+ +F+P C K G++ L+V V +S T +++ L S + + D ILPG ++K +LK + GS+
Sbjct: 66 LNMDTLQEDMLVMGVVKELTATALQIALPGRMFARTLVADISDAYTRVAKAAMSGDTS---EYHDLTELFQLGRIVYGKAIKTEKLDTGRVSLLLSLKPADVHGNLHHKSIKKGFIFSGAVAEALEHGYVIESGVQGLQAFVP---CEKPAQKLHVGQLAFLKVKTVHHDTHQSTCT--CVQVEQDQLRIKSQNETNLDYILPGSIVKFKVAKHLKDGLKGSI 280
BLAST of Programmed cell death 11 vs. Ensembl Zebrafish
Match: pdcd11 (programmed cell death 11 [Source:ZFIN;Acc:ZDB-GENE-030131-4076]) HSP 1 Score: 258.07 bits (658), Expect = 6.643e-69 Identity = 231/890 (25.96%), Postives = 410/890 (46.07%), Query Frame = 3
Query: 60 SILLGRIKEIHEFKLIISLPHNKSGVCRIANISEEYNKLINEFNEDKSIMNEVARLNQLFSKGQIVQVKLTKNSSNKKN----ELSMIPSEINCNINANRLKQGIKLQVAIKSREDKGYILETGIGGINSFLPF-TECSNAEYKTGKMLEVFPVITPEKKSRVTNFTTDIQKR-NLVHSSFDPCDFDVILPGMLIKTYLKLSIDGSLEGKFHGFPVCVQPIHHKITDQIST-----ELTMCVIGIDLSLKQLDCSLLSHLKPPFKGSTDL-LDVCIGYSEKNCTVTK-RDKTKIVISIPDKKYVTGFIAKGHIDPKLQKTDIG-----SNVIVRYLDYNLIDNVIHATTLNSLLAQSYFSIHQAKLGEIIKGKVLSFSKHGFTVKISSNLTGLIPIPHLSDKPMSNAQKLLAPGDQVQCRVFHIDLLENRLLLTIKKSLMTSTLPIISGISDLQTGMILCGFVAKIFDFGLVVIMFNNVKGWVPIGRVPESKRKSLRVAYYVGKPVEVKVIRWEVATNKIELSLKE--ESTIDEEVIEKNPVNDLEIGDIYEAVITKARVDGFNVRLCPSNKVAFLPFIHLSDSREHRKLFEAHYRMSEKDQLKXXXXXXXXXXXXXXXSKKKSLIEAAVKNEVVKSNNSLTINSQWIGWVIKNESFGLLVELPSGVKGLVRNKDISDILPLSGQSRDLFEIGDTVMAKIIELDPLNLNRILFTLKMSSTYRASEHLVKSINFLIHHFEERKFLKSTVSCKN-------VSKLNLGDLVEVKITKQCEWGYT-LTLNNDDSVTGFIRNEHLPNSPITETSVRNAIIIDIDLKDQAIEVTMVNSYVNALSHRRNDCTRIEVDQNIASDVLGFNKDFVVSIFQGHAGGNLVFIPTKRFWNDI 2645
+++LG +KE+ +F++++ LP G I NI + Y ++N+ + + EV L++LF+ G +++ ++ S K+ +LS+ P ++N +N+ LK + L ++S ED GY+++ GIGG +FLP + S + G+ + V + + RV + + Q + D +LPG+LI +K L F V H D+ ST E+ ++ + S +Q+ SL SHL PP DL +G + C +T + ++ + D F+ + + ++ D + I+R ++Y+ I+ + AT S + +FS K+G+I++G V KHG V+I ++ G+IP HL+D + N +K PG +V+CRV ++ + L+LT KK+L+ STLPI SD + G I GFV I +FG +V + +VKG VP+ + + ++VG+ V+VKV++ + + LS K E + EE I K D +G + +A + + ++G V + P AFLP HLSD + + E D + + + N ++++KK L + K+ + L + Q +GWV +G+ + P GV GL ++ D ++ +F+I TV+AK+ LD ++ + +E + LI +ER+ + + + +S L +GD +++ + E G LT + VT H +T NA+I+ ID + V++ L+ ++ ++E D + V +KDF V +L F PT+ N I
Sbjct: 82 TLMLGCVKEVSDFEVVVGLPSGLVGYLPICNICDAYTNILNDKLDTDDGLEEVVPLSKLFTLGMLIRCVVSSLDSAKEGHISLKLSINPKDVNKALNSVALKPAMTLSGCVESVEDHGYLVDIGIGGTKAFLPKKSTSSKQDLYVGQYVLVL-IEDVKDSGRVVRLSQNPQALVKACAQTKQGWTLDNLLPGLLIHGCVKRVTPHGLIVTFLSSFTGVVDFLHLDEDKESTYSKGQEILARILYVQPSTRQVGLSLRSHLLPPGGAVLDLHFSERVGEVVQGCQMTSLHHYSGALMKMLDGS--RAFVHRNLLKEPKEELDTNHLMSQTQHILRIINYSPIEQIYQATLRWSSIETPFFSCQDIKVGQIVEGTVTDLQKHGVYVRIGEHIRGMIPRIHLADVTLKNPEKKFYPGLKVKCRVLLVEAQKKLLILTRKKALVESTLPIFQSYSDARPGRISHGFVVCIKEFGCIVRFYEDVKGLVPMQELTTETVTNPEELFFVGQVVKVKVLKCDEEKKMLRLSFKSVTEEDVREEQIAK---FDFIVGKMVDARVCRKVLNGLEVSIIPEEVQAFLPTTHLSDHVTN--CLPLWMALEEGDTICNLMCLTNYKKKGIVLTKKPHLKAYIEDGAIPKNFSELQVGMQMVGWVKNIMPYGVFISFPYGVFGLAPIANMGD--QFIKETSGIFDIDQTVVAKVTNLDEEKQRFLVSLKLSELSLSENEFHTR----LIQGLKERRNISEMRAGRGDSDVLWKLSALTVGDQMKMIVGDTTEDGSVMLTSDQLSGVTVLASKYHKEGVNLTPGCKLNAVILHIDFVKSQVHVSLRPK----LNIKKE---KLEKDARFTAKVQFADKDFAVVSLA--TTSDLTFFPTRPHLNSI 948
BLAST of Programmed cell death 11 vs. Ensembl Xenopus
Match: PDCD11 (programmed cell death 11 [Source:NCBI gene;Acc:100327235]) HSP 1 Score: 224.557 bits (571), Expect = 1.936e-58 Identity = 238/905 (26.30%), Postives = 421/905 (46.52%), Query Frame = 3
Query: 63 ILLGRIKEIHEFKLIISLPHNKSGVCRIANISEEYNKLINEFNEDKSIMNEVARLNQLFSKGQIVQVKL----TKNSSNKKNELSMIPSEINCNINANRLKQGIKLQVAIKSREDKGYILETGIGGINSFLPFTECSNAEYKTGK-----MLEVFPVITPEKK--SRVTNFTTDIQKRNLVHSSFDPCD----FDVILPGMLIKTYL----KLSIDGSLEGKFHGFPVCVQPIHHKITD-QISTELTMCVIGIDLSLKQLDCSLLSHLKPPFKGSTDLLDVCIGYSEKNCTVTKRDKTKIVISIPDKKYVTGFI------AKGHIDPKLQKTDIGSNVIVRYLDYNLIDNVIHATTLNSLLAQSYFSIHQ-AKLGEIIKGKVLSFSKHGFTVKISSNLTGLIPIPHLSDKPMSNAQKLLAPGDQVQCRVFHIDLLENRLLLTIKKSLMTSTLPIISGISDLQTGMILCGFVAKIFDFGLVVIMFNNVKGWVP---IGRVPESKRKSLRVAYYVGKPVEVKVIRWEVATNKIELSLK----EESTIDEEVIEKNPVNDLEIGDIYEAVITKARVDGFNVRLCPSNKVAFLPFIHLSDSREHRKLFEAHYRMSEKDQLKXXXXXXXXXXXXXXXSKKKSLIEAAVKNEVVKSNNSLTINSQWIGWVIKNESFGLLVELPSGVKGLVRNKDISDILPLSGQSRDLFEIGDTVMAKIIELDPLNLNRILFTLKMSSTYRASEHLVKSINFLIHHFEERKFLKSTVSCK-------NVSKLNLGDLVEVKITKQCEWG----YTLTLNNDDSVTGFIRNEHLPNSPITETSVRNAIIIDIDLKDQAIEVTMVNSYVNALSHRRNDCTRIEVDQNIASDVLGFNKDFVVSIFQGHAGGNLVFIPTKRFWND 2642
+ LG +K+ +F+L +SLP+ +G + NI E Y KLI E + M + L++L+S G +V+ + T S +LS+ P +N + LK G+ + + S ED GY+++ G+ G +FLP + + GK + + + E K R+ + +N V + + + +LPG+++K + + SI S + GF + KI + E+ C++ +D S K + +L + P L +G +NC V + I D + GF A H D ++ K G+ R +++ ++ +H +L + F H+ + G++++G + S G VKI+ +LTGL+P H +D + + +K G++++C+V + E +L+LT KK+LM S LPII+ D Q G+I GF+ I D+G +V FN V+G P +G + E SL A+Y G+ ++V+V+ T K+ LS + E+ ++ ++K L++G + + + G NV + P AF+P +HLSD + +L + + E D + V+ ++ + I++KK LI + K VK + + G+V +G VE P G+ GLV +ISD ++ S LFE G TV+AK+I+ D R L TLKMS S+ + + L F E + LK +S K ++ L G + + + E G T ++ +V+ N +PI V+ A+++ +DL +++ + S AL ++ + ++ + + ++DVL ++F V G A +L +P ND
Sbjct: 83 MFLGCVKQAKDFELAVSLPYCLTGYIQATNICEAYTKLIGEQVKKDDPMEALTPLSELYSPGMLVRCAISSLETTTSGCNSVKLSINPKHVNKALTTGSLKAGMLVSGCVSSVEDHGYLVDIGVTGSKAFLPRQKAQLFLNQAGKGPLLRIGQYLNCVIQEVKNEGRIVRLSIT---QNDVTGALATMEQNWTLNNLLPGLVLKAQIEKVTQSSITLSFLSSYTGFVDFLHFEPKKIGSYKEGQEVKACILWLDPSTKSIRLTLRQCFQQPGNPLPQLTSDWVGSVLENCMVQTLVRNAGAIFELDGGNL-GFAFKHNLSASKHPDNEIFKK--GTAHKGRIKEFSPMEE-MHFLSLREKMITDLFLRHEDIQAGQVLEGTIQSLEAVGLVVKITDHLTGLVPKLHFADVLLKHPEKKYIIGNKIKCKVLTVITSERKLILTRKKTLMKSKLPIIASFDDAQPGLITHGFIVAIKDYGCIVKFFNEVQGLAPRRELGSLQEI--SSLEDAFYRGQVIKVRVLDCNPQTQKLLLSFRITEEGETEQEQRYLKKTKAVKLDVGKVVDTRVVSKTDKGVNVLILPEESPAFIPKMHLSDHISNCELL--WHALEEGDNIP-GVMCLSTFKGHHILTKKAVLISSFEKGSCVKVISEVQTGMHLTGFVKSIMPYGAFVEFPYGLFGLVPKSEISDKF-VTNISDHLFE-GQTVLAKVIKTDE-EKQRFLLTLKMSEC-APSDCSAEGLLLLSQCFSELQLLKGLLSRKGDPEDELSIYTLTSGQKLTLVVENAEENGPVHFSTGSITGAQTVSA-THNNIGDETPIAGQKVK-AVVLHVDL----LKLHVYVSLNEALLKKKKNVPKM--NSSHSADVLHVAEEFAVVSLAGPA--HLAAVPMSSHLND 961 HSP 2 Score: 65.4698 bits (158), Expect = 7.882e-10 Identity = 58/256 (22.66%), Postives = 112/256 (43.75%), Query Frame = 3
Query: 3684 KLTNVKKEILIRTAEKRRETGESLKNPTTETEFELLIFNHPHDSNAWIKFMNFYLENDKNIDKARSIAERAMKMLLSNDIENRFQLMKKYMLLEIDELVAKKDD-VSYDDQLIRFRELCQRAMTQKAKQMYIHVCKNLINAKLFDLAEELSKRFIKDFPNDSVSW--FHLFLIRFSQKKYLVVRETLVNAQRSLSVADFRDLTIRVAQAEIEQGDVSRGVQSLVDIFQNRPKDISLKNRIVSILENNGLSEHVSKI 4442
+L KKE ++K +S + P + +F+ L+ + P S W+++M F+L + I+KAR +AERA+K + + + + + LL ++ + ++ V ++ +++ E ++Y + + ++ F AE+L +K F + W F FL++ Q L A +SL D D+ + AQ E + GD R + PK L + + ++ +G V I
Sbjct: 1516 ELAREKKEAEKELSKKEAALQDSGRQPQSADDFDRLVISSPDSSILWLQYMAFHL-HATEIEKARVVAERALKTISFREEQEKLNVW--VALLNLENMYGTEESLVKAFERAVQYNEPL---------KVYQQLADIYVKSEKFKQAEDLYNTMLKRFRQEKSVWIKFATFLLKQGQGDG--THRLLQRALKSLPEKDHVDVISKFAQLEFQLGDSERAKALFESTLSSYPKRTDLWSVYIDMMVKHGSQREVRDI 1757
BLAST of Programmed cell death 11 vs. Ensembl Xenopus
Match: PDCD11 (programmed cell death 11 [Source:NCBI gene;Acc:100327235]) HSP 1 Score: 224.172 bits (570), Expect = 2.620e-58 Identity = 238/905 (26.30%), Postives = 421/905 (46.52%), Query Frame = 3
Query: 63 ILLGRIKEIHEFKLIISLPHNKSGVCRIANISEEYNKLINEFNEDKSIMNEVARLNQLFSKGQIVQVKL----TKNSSNKKNELSMIPSEINCNINANRLKQGIKLQVAIKSREDKGYILETGIGGINSFLPFTECSNAEYKTGK-----MLEVFPVITPEKK--SRVTNFTTDIQKRNLVHSSFDPCD----FDVILPGMLIKTYL----KLSIDGSLEGKFHGFPVCVQPIHHKITD-QISTELTMCVIGIDLSLKQLDCSLLSHLKPPFKGSTDLLDVCIGYSEKNCTVTKRDKTKIVISIPDKKYVTGFI------AKGHIDPKLQKTDIGSNVIVRYLDYNLIDNVIHATTLNSLLAQSYFSIHQ-AKLGEIIKGKVLSFSKHGFTVKISSNLTGLIPIPHLSDKPMSNAQKLLAPGDQVQCRVFHIDLLENRLLLTIKKSLMTSTLPIISGISDLQTGMILCGFVAKIFDFGLVVIMFNNVKGWVP---IGRVPESKRKSLRVAYYVGKPVEVKVIRWEVATNKIELSLK----EESTIDEEVIEKNPVNDLEIGDIYEAVITKARVDGFNVRLCPSNKVAFLPFIHLSDSREHRKLFEAHYRMSEKDQLKXXXXXXXXXXXXXXXSKKKSLIEAAVKNEVVKSNNSLTINSQWIGWVIKNESFGLLVELPSGVKGLVRNKDISDILPLSGQSRDLFEIGDTVMAKIIELDPLNLNRILFTLKMSSTYRASEHLVKSINFLIHHFEERKFLKSTVSCK-------NVSKLNLGDLVEVKITKQCEWG----YTLTLNNDDSVTGFIRNEHLPNSPITETSVRNAIIIDIDLKDQAIEVTMVNSYVNALSHRRNDCTRIEVDQNIASDVLGFNKDFVVSIFQGHAGGNLVFIPTKRFWND 2642
+ LG +K+ +F+L +SLP+ +G + NI E Y KLI E + M + L++L+S G +V+ + T S +LS+ P +N + LK G+ + + S ED GY+++ G+ G +FLP + + GK + + + E K R+ + +N V + + + +LPG+++K + + SI S + GF + KI + E+ C++ +D S K + +L + P L +G +NC V + I D + GF A H D ++ K G+ R +++ ++ +H +L + F H+ + G++++G + S G VKI+ +LTGL+P H +D + + +K G++++C+V + E +L+LT KK+LM S LPII+ D Q G+I GF+ I D+G +V FN V+G P +G + E SL A+Y G+ ++V+V+ T K+ LS + E+ ++ ++K L++G + + + G NV + P AF+P +HLSD + +L + + E D + V+ ++ + I++KK LI + K VK + + G+V +G VE P G+ GLV +ISD ++ S LFE G TV+AK+I+ D R L TLKMS S+ + + L F E + LK +S K ++ L G + + + E G T ++ +V+ N +PI V+ A+++ +DL +++ + S AL ++ + ++ + + ++DVL ++F V G A +L +P ND
Sbjct: 83 MFLGCVKQAKDFELAVSLPYCLTGYIQATNICEAYTKLIGEQVKKDDPMEALTPLSELYSPGMLVRCAISSLETTTSGCNSVKLSINPKHVNKALTTGSLKAGMLVSGCVSSVEDHGYLVDIGVTGSKAFLPRQKAQLFLNQAGKGPLLRIGQYLNCVIQEVKNEGRIVRLSIT---QNDVTGALATMEQNWTLNNLLPGLVLKAQIEKVTQSSITLSFLSSYTGFVDFLHFEPKKIGSYKEGQEVKACILWLDPSTKSIRLTLRQCFQQPGNPLPQLTSDWVGSVLENCMVQTLVRNAGAIFELDGGNL-GFAFKHNLSASKHPDNEIFKK--GTAHKGRIKEFSPMEE-MHFLSLREKMITDLFLRHEDIQAGQVLEGTIQSLEAVGLVVKITDHLTGLVPKLHFADVLLKHPEKKYIIGNKIKCKVLTVITSERKLILTRKKTLMKSKLPIIASFDDAQPGLITHGFIVAIKDYGCIVKFFNEVQGLAPRRELGSLQEI--SSLEDAFYRGQVIKVRVLDCNPQTQKLLLSFRITEEGETEQEQRYLKKTKAVKLDVGKVVDTRVVSKTDKGVNVLILPEESPAFIPKMHLSDHISNCELL--WHALEEGDNIP-GVMCLSTFKGHHILTKKAVLISSFEKGSCVKVISEVQTGMHLTGFVKSIMPYGAFVEFPYGLFGLVPKSEISDKF-VTNISDHLFE-GQTVLAKVIKTDE-EKQRFLLTLKMSEC-APSDCSAEGLLLLSQCFSELQLLKGLLSRKGDPEDELSIYTLTSGQKLTLVVENAEENGPVHFSTGSITGAQTVSA-THNNIGDETPIAGQKVK-AVVLHVDL----LKLHVYVSLNEALLKKKKNVPKM--NSSHSADVLHVAEEFAVVSLAGPA--HLAAVPMSSHLND 961 HSP 2 Score: 65.4698 bits (158), Expect = 8.540e-10 Identity = 58/256 (22.66%), Postives = 112/256 (43.75%), Query Frame = 3
Query: 3684 KLTNVKKEILIRTAEKRRETGESLKNPTTETEFELLIFNHPHDSNAWIKFMNFYLENDKNIDKARSIAERAMKMLLSNDIENRFQLMKKYMLLEIDELVAKKDD-VSYDDQLIRFRELCQRAMTQKAKQMYIHVCKNLINAKLFDLAEELSKRFIKDFPNDSVSW--FHLFLIRFSQKKYLVVRETLVNAQRSLSVADFRDLTIRVAQAEIEQGDVSRGVQSLVDIFQNRPKDISLKNRIVSILENNGLSEHVSKI 4442
+L KKE ++K +S + P + +F+ L+ + P S W+++M F+L + I+KAR +AERA+K + + + + + LL ++ + ++ V ++ +++ E ++Y + + ++ F AE+L +K F + W F FL++ Q L A +SL D D+ + AQ E + GD R + PK L + + ++ +G V I
Sbjct: 1474 ELAREKKEAEKELSKKEAALQDSGRQPQSADDFDRLVISSPDSSILWLQYMAFHL-HATEIEKARVVAERALKTISFREEQEKLNVW--VALLNLENMYGTEESLVKAFERAVQYNEPL---------KVYQQLADIYVKSEKFKQAEDLYNTMLKRFRQEKSVWIKFATFLLKQGQGDG--THRLLQRALKSLPEKDHVDVISKFAQLEFQLGDSERAKALFESTLSSYPKRTDLWSVYIDMMVKHGSQREVRDI 1715
BLAST of Programmed cell death 11 vs. Ensembl Xenopus
Match: PDCD11 (programmed cell death 11 [Source:NCBI gene;Acc:100327235]) HSP 1 Score: 211.075 bits (536), Expect = 2.816e-54 Identity = 233/898 (25.95%), Postives = 406/898 (45.21%), Query Frame = 3
Query: 63 ILLGRIKEIHEFKLIISLPHNKSGVCRIANISEEYNKLINEFNEDKSIMNEVARLNQLFSKGQIVQVKL----TKNSSNKKNELSMIPSEINCNINANRLKQGIKLQVAIKSREDKGYILETGIGGINSFLPFTECSNAEYKTGK-----MLEVFPVITPEKK--SRVTNFTTDIQKRNLVHSSFDPCD----FDVILPGMLIKTYL----KLSIDGSLEGKFHGFPVCVQPIHHKITD-QISTELTMCVIGIDLSLKQLDCSLLSHLKPPFKGSTDLLDVCIGYSEKNCTVTKRDKTKIVISIPDKKYVTGFIAKGHIDPKLQKTDIGSNVIVRYLDYNLIDNVIHATTLNSLLAQSYFSIHQAKLGEIIKGKVLSFSKHGFTVKISSNLTGLIPIPHLSDKPMSNAQKLLAPGDQVQCRVFHIDLLENRLLLTIKKSLMTSTLPIISGISDLQTGMILCGFVAKIFDFGLVVIMFNNVKGWVP---IGRVPESKRKSLRVAYYVGKPVEVKVIRWEVATNKIELSLK----EESTIDEEVIEKNPVNDLEIGDIYEAVITKARVDGFNVRLCPSNKVAFLPFIHLSDSREHRKLFEAHYRMSEKDQLKXXXXXXXXXXXXXXXSKKKSLIEAAVKNEVVKSNNSLTINSQWIGWVIKNESFGLLVELPSGVKGLVRNKDISDILPLSGQSRDLFEIGDTVMAKIIELDPLNLNRILFTLKMSSTYRASEHLVKSINFLIHHFEERKFLKSTVSCK-------NVSKLNLGDLVEVKITKQCEWG----YTLTLNNDDSVTGFIRNEHLPNSPITETSVRNAIIIDIDLKDQAIEVTMVNSYVNALSHRRNDCTRIEVDQNIASDVLGFNKDFVVSIFQGHAGGNLVFIPTKRFWND 2642
+ LG +K+ +F+L +SLP+ +G + NI E Y KLI E + M + L++L+S G +V+ + T S +LS+ P +N + LK G+ + + S ED GY+++ G+ G +FLP + + GK + + + E K R+ + +N V + + + +LPG+++K + + SI S + GF + KI + E+ C++ +D S K + +L + P L +G +NC V + I D + GF K + L + N I + H + + + I+ G + S G VKI+ +LTGL+P H +D + + +K G++++C+V + E +L+LT KK+LM S LPII+ D Q G+I GF+ I D+G +V FN V+G P +G + E SL A+Y G+ ++V+V+ T K+ LS + E+ ++ ++K L++G + + + G NV + P AF+P +HLSD + +L + + E D + V+ ++ + I++KK LI + K VK + + G+V +G VE P G+ GLV +ISD ++ S LFE G TV+AK+I+ D R L TLKMS S+ + + L F E + LK +S K ++ L G + + + E G T ++ +V+ N +PI V+ A+++ +DL +++ + S AL ++ + ++ + + ++DVL ++F V G A +L +P ND
Sbjct: 83 MFLGCVKQAKDFELAVSLPYCLTGYIQATNICEAYTKLIGEQVKKDDPMEALTPLSELYSPGMLVRCAISSLETTTSGCNSVKLSINPKHVNKALTTGSLKAGMLVSGCVSSVEDHGYLVDIGVTGSKAFLPRQKAQLFLNQAGKGPLLRIGQYLNCVIQEVKNEGRIVRLSIT---QNDVTGALATMEQNWTLNNLLPGLVLKAQIEKVTQSSITLSFLSSYTGFVDFLHFEPKKIGSYKEGQEVKACILWLDPSTKSIRLTLRQCFQQPGNPLPQLTSDWVGSVLENCMVQTLVRNAGAIFELDGGNL-GFAFKHN----LSASKHPDNEIFK-------KGTAHKGRIKEFIITCSWCIN---------GTIQSLEAVGLVVKITDHLTGLVPKLHFADVLLKHPEKKYIIGNKIKCKVLTVITSERKLILTRKKTLMKSKLPIIASFDDAQPGLITHGFIVAIKDYGCIVKFFNEVQGLAPRRELGSLQEI--SSLEDAFYRGQVIKVRVLDCNPQTQKLLLSFRITEEGETEQEQRYLKKTKAVKLDVGKVVDTRVVSKTDKGVNVLILPEESPAFIPKMHLSDHISNCELL--WHALEEGDNIP-GVMCLSTFKGHHILTKKAVLISSFEKGSCVKVISEVQTGMHLTGFVKSIMPYGAFVEFPYGLFGLVPKSEISDKF-VTNISDHLFE-GQTVLAKVIKTDE-EKQRFLLTLKMSEC-APSDCSAEGLLLLSQCFSELQLLKGLLSRKGDPEDELSIYTLTSGQKLTLVVENAEENGPVHFSTGSITGAQTVSA-THNNIGDETPIAGQKVK-AVVLHVDL----LKLHVYVSLNEALLKKKKNVPKM--NSSHSADVLHVAEEFAVVSLAGPA--HLAAVPMSSHLND 937 HSP 2 Score: 65.855 bits (159), Expect = 7.228e-10 Identity = 58/256 (22.66%), Postives = 112/256 (43.75%), Query Frame = 3
Query: 3684 KLTNVKKEILIRTAEKRRETGESLKNPTTETEFELLIFNHPHDSNAWIKFMNFYLENDKNIDKARSIAERAMKMLLSNDIENRFQLMKKYMLLEIDELVAKKDD-VSYDDQLIRFRELCQRAMTQKAKQMYIHVCKNLINAKLFDLAEELSKRFIKDFPNDSVSW--FHLFLIRFSQKKYLVVRETLVNAQRSLSVADFRDLTIRVAQAEIEQGDVSRGVQSLVDIFQNRPKDISLKNRIVSILENNGLSEHVSKI 4442
+L KKE ++K +S + P + +F+ L+ + P S W+++M F+L + I+KAR +AERA+K + + + + + LL ++ + ++ V ++ +++ E ++Y + + ++ F AE+L +K F + W F FL++ Q L A +SL D D+ + AQ E + GD R + PK L + + ++ +G V I
Sbjct: 1492 ELAREKKEAEKELSKKEAALQDSGRQPQSADDFDRLVISSPDSSILWLQYMAFHL-HATEIEKARVVAERALKTISFREEQEKLNVW--VALLNLENMYGTEESLVKAFERAVQYNE---------PLKVYQQLADIYVKSEKFKQAEDLYNTMLKRFRQEKSVWIKFATFLLKQGQGDG--THRLLQRALKSLPEKDHVDVISKFAQLEFQLGDSERAKALFESTLSSYPKRTDLWSVYIDMMVKHGSQREVRDI 1733
BLAST of Programmed cell death 11 vs. Ensembl Xenopus
Match: PDCD11 (programmed cell death 11 [Source:NCBI gene;Acc:100327235]) HSP 1 Score: 201.83 bits (512), Expect = 1.763e-51 Identity = 209/766 (27.28%), Postives = 351/766 (45.82%), Query Frame = 3
Query: 63 ILLGRIKEIHEFKLIISLPHNKSGVCRIANISEEYNKLINEFNEDKSIMNEVARLNQLFSKGQIVQVKL----TKNSSNKKNELSMIPSEINCNINANRLKQGIKLQVAIKSREDKGYILETGIGGINSFLPFTECSNAEYKTGK-----MLEVFPVITPEKK--SRVTNFTTDIQKRNLVHSSFDPCD----FDVILPGMLIKTYL----KLSIDGSLEGKFHGFPVCVQPIHHKI-TDQISTELTMCVIGIDLSLKQLDCSLLSHLKPPFKGSTDLLDVCIGYSEKNCTVTKRDKTKIVISIPDKKYVTGFIAKGHIDPKLQKTDIGSNVIVRYLDYNLIDNVIHATTLNSLLAQSYFSIHQAKLGEII-------KGKVLSFSKHGFTVKISSNLTGLIPIPHLSDKPMSNAQKLLAPGDQVQCRVFHIDLLENRLLLTIKKSLMTSTLPIISGISDLQTGMILCGFVAKIFDFGLVVIMFNNVKGWVP---IGRVPESKRKSLRVAYYVGKPVEVKVIRWEVATNKIELSLK----EESTIDEEVIEKNPVNDLEIGDIYEAVITKARVD-GFNVRLCPSNKVAFLPFIHLSDSREHRKLFEAHYRMSEKDQLKXXXXXXXXXXXXXXXSKKKSLIEAAVKNEVVKSNNSLTINSQWIGWVIKNESFGLLVELPSGVKGLVRNKDISDILPLSGQSRDLFEIGDTVMAKIIELDPLNLNRILFTLKMSSTYRASEHLVKSINFLIHHFEERKFLKSTVSCKN 2255
+ LG +K+ +F+L +SLP+ +G + NI E Y KLI E + M + L++L+S G +V+ + T S +LS+ P +N + LK G+ + + S ED GY+++ G+ G +FLP + + GK + + + E K R+ + +N V + + + +LPG+++K + + SI S + GF + KI + + E+ C++ +D S K + +L + P L +G +NC V + I D + GF K ++ DN I + H+ ++ E I G + S G VKI+ +LTGL+P H +D + + +K G++++C+V + E +L+LT KK+LM S LPII+ D Q G+I GF+ I D+G +V FN V+G P +G + E SL A+Y G+ ++V+V+ T K+ LS + E+ ++ ++K L++G V+ ++ D G NV + P AF+P +HLSD + +L + + E D + V+ ++ + I++KK LI + K VK + + G+V +G VE P G+ GLV +ISD ++ S LFE G TV+AK+I+ D R L TLKMS S+ + + L F E + LK +S K+
Sbjct: 2 MFLGCVKQAKDFELAVSLPYCLTGYIQATNICEAYTKLIGEQVKKDDPMEALTPLSELYSPGMLVRCAISSLETTTSGCNSVKLSINPKHVNKALTTGSLKAGMLVSGCVSSVEDHGYLVDIGVTGSKAFLPRQKAQLFLNQAGKGPLLRIGQYLNCVIQEVKNEGRIVRLSIT---QNDVTGALATMEQNWTLNNLLPGLVLKAQIEKVTQSSITLSFLSSYTGFVDFLHFEPKKIGSYKEGQEVKACILWLDPSTKSIRLTLRQCFQQPGNPLPQLTSDWVGSVLENCMVQTLVRNAGAIFELDGGNL-GFAFKHNLSASKHP-----------------DNEIFKKG----------TAHKGRIKEFIITCSWCINGTIQSLEAVGLVVKITDHLTGLVPKLHFADVLLKHPEKKYIIGNKIKCKVLTVITSERKLILTRKKTLMKSKLPIIASFDDAQPGLITHGFIVAIKDYGCIVKFFNEVQGLAPRRELGSLQEI--SSLEDAFYRGQVIKVRVLDCNPQTQKLLLSFRITEEGETEQEQRYLKKTKAVKLDVGK----VLFVSKTDKGVNVLILPEESPAFIPKMHLSDHISNCELL--WHALEEGDNIP-GVMCLSTFKGHHILTKKAVLISSFEKGSCVKVISEVQTGMHLTGFVKSIMPYGAFVEFPYGLFGLVPKSEISDKF-VTNISDHLFE-GQTVLAKVIKTDE-EKQRFLLTLKMSEC-APSDCSAEGLLLLSQCFSELQLLKGLLSRKD 723 HSP 2 Score: 58.9214 bits (141), Expect = 7.866e-8 Identity = 56/248 (22.58%), Postives = 110/248 (44.35%), Query Frame = 3
Query: 3684 KLTNVKKEILIRTAEKRRETGESLKNPTTETEFELLIFNHPHDSNAWIKFMNFYLENDKNIDKARSIAERAMKMLLSNDIENRFQLMKKYMLLEIDELVAKKDD-VSYDDQLIRFRELCQRAMTQKAKQMYIHVCKNLINAKLFDLAEELSKRFIKDFPNDSVSW--FHLFLIRFSQKKYLVVRETLVNAQRSLSVADFRDLTIRVAQAEIEQGDVSRGVQSLVDIFQNRPKDISLKNRIVSILENNG 4418
+L KKE ++K +S + P + +F+ L+ + P S W+++M F+L + I+KAR +AERA+K + + + + + LL ++ + ++ V ++ +++ E ++Y + + ++ F AE+L +K F + W F FL++ Q L A +SL D D+ + AQ E + GD R + PK L + + ++ +G
Sbjct: 1269 ELAREKKEAEKELSKKEAALQDSGRQPQSADDFDRLVISSPDSSILWLQYMAFHL-HATEIEKARVVAERALKTISFREEQEKLNVW--VALLNLENMYGTEESLVKAFERAVQYNE---------PLKVYQQLADIYVKSEKFKQAEDLYNTMLKRFRQEKSVWIKFATFLLKQGQGDG--THRLLQRALKSLPEKDHVDVISKFAQLEFQLGDSERAKALFESTLSSYPKRTDLWSVYIDMMVKHG 1502
BLAST of Programmed cell death 11 vs. Ensembl Xenopus
Match: PDCD11 (programmed cell death 11 [Source:NCBI gene;Acc:100327235]) HSP 1 Score: 199.134 bits (505), Expect = 1.246e-50 Identity = 208/762 (27.30%), Postives = 350/762 (45.93%), Query Frame = 3
Query: 63 ILLGRIKEIHEFKLIISLPHNKSGVCRIANISEEYNKLINEFNEDKSIMNEVARLNQLFSKGQIVQVKL----TKNSSNKKNELSMIPSEINCNINANRLKQGIKLQVAIKSREDKGYILETGIGGINSFLPFTECSNAEYKTGK-----MLEVFPVITPEKK--SRVTNFTTDIQKRNLVHSSFDPCD----FDVILPGMLIKTYL----KLSIDGSLEGKFHGFPVCVQPIHHKI-TDQISTELTMCVIGIDLSLKQLDCSLLSHLKPPFKGSTDLLDVCIGYSEKNCTVTKRDKTKIVISIPDKKYVTGFIAKGHIDPKLQKTDIGSNVIVRYLDYNLIDNVIHATTLNSLLAQSYFSIHQAKLGEII---KGKVLSFSKHGFTVKISSNLTGLIPIPHLSDKPMSNAQKLLAPGDQVQCRVFHIDLLENRLLLTIKKSLMTSTLPIISGISDLQTGMILCGFVAKIFDFGLVVIMFNNVKGWVP---IGRVPESKRKSLRVAYYVGKPVEVKVIRWEVATNKIELSLK----EESTIDEEVIEKNPVNDLEIGDIYEAVITKARVD-GFNVRLCPSNKVAFLPFIHLSDSREHRKLFEAHYRMSEKDQLKXXXXXXXXXXXXXXXSKKKSLIEAAVKNEVVKSNNSLTINSQWIGWVIKNESFGLLVELPSGVKGLVRNKDISDILPLSGQSRDLFEIGDTVMAKIIELDPLNLNRILFTLKMSSTYRASEHLVKSINFLIHHFEERKFLKSTVSCKN 2255
+ LG +K+ +F+L +SLP+ +G + NI E Y KLI E + M + L++L+S G +V+ + T S +LS+ P +N + LK G+ + + S ED GY+++ G+ G +FLP + + GK + + + E K R+ + +N V + + + +LPG+++K + + SI S + GF + KI + + E+ C++ +D S K + +L + P L +G +NC V + I D + GF K ++ DN I + H+ ++ E I + S G VKI+ +LTGL+P H +D + + +K G++++C+V + E +L+LT KK+LM S LPII+ D Q G+I GF+ I D+G +V FN V+G P +G + E SL A+Y G+ ++V+V+ T K+ LS + E+ ++ ++K L++G V+ ++ D G NV + P AF+P +HLSD + +L + + E D + V+ ++ + I++KK LI + K VK + + G+V +G VE P G+ GLV +ISD ++ S LFE G TV+AK+I+ D R L TLKMS S+ + + L F E + LK +S K+
Sbjct: 2 MFLGCVKQAKDFELAVSLPYCLTGYIQATNICEAYTKLIGEQVKKDDPMEALTPLSELYSPGMLVRCAISSLETTTSGCNSVKLSINPKHVNKALTTGSLKAGMLVSGCVSSVEDHGYLVDIGVTGSKAFLPRQKAQLFLNQAGKGPLLRIGQYLNCVIQEVKNEGRIVRLSIT---QNDVTGALATMEQNWTLNNLLPGLVLKAQIEKVTQSSITLSFLSSYTGFVDFLHFEPKKIGSYKEGQEVKACILWLDPSTKSIRLTLRQCFQQPGNPLPQLTSDWVGSVLENCMVQTLVRNAGAIFELDGGNL-GFAFKHNLSASKHP-----------------DNEIFKKG----------TAHKGRIKEFIITCSWCINSLEAVGLVVKITDHLTGLVPKLHFADVLLKHPEKKYIIGNKIKCKVLTVITSERKLILTRKKTLMKSKLPIIASFDDAQPGLITHGFIVAIKDYGCIVKFFNEVQGLAPRRELGSLQEI--SSLEDAFYRGQVIKVRVLDCNPQTQKLLLSFRITEEGETEQEQRYLKKTKAVKLDVGK----VLFVSKTDKGVNVLILPEESPAFIPKMHLSDHISNCELL--WHALEEGDNIP-GVMCLSTFKGHHILTKKAVLISSFEKGSCVKVISEVQTGMHLTGFVKSIMPYGAFVEFPYGLFGLVPKSEISDKF-VTNISDHLFE-GQTVLAKVIKTDE-EKQRFLLTLKMSEC-APSDCSAEGLLLLSQCFSELQLLKGLLSRKD 719 HSP 2 Score: 59.3066 bits (142), Expect = 7.100e-8 Identity = 58/256 (22.66%), Postives = 112/256 (43.75%), Query Frame = 3
Query: 3684 KLTNVKKEILIRTAEKRRETGESLKNPTTETEFELLIFNHPHDSNAWIKFMNFYLENDKNIDKARSIAERAMKMLLSNDIENRFQLMKKYMLLEIDELVAKKDD-VSYDDQLIRFRELCQRAMTQKAKQMYIHVCKNLINAKLFDLAEELSKRFIKDFPNDSVSW--FHLFLIRFSQKKYLVVRETLVNAQRSLSVADFRDLTIRVAQAEIEQGDVSRGVQSLVDIFQNRPKDISLKNRIVSILENNGLSEHVSKI 4442
+L KKE ++K +S + P + +F+ L+ + P S W+++M F+L + I+KAR +AERA+K + + + + + LL ++ + ++ V ++ +++ E ++Y + + ++ F AE+L +K F + W F FL++ Q L A +SL D D+ + AQ E + GD R + PK L + + ++ +G V I
Sbjct: 1191 ELAREKKEAEKELSKKEAALQDSGRQPQSADDFDRLVISSPDSSILWLQYMAFHL-HATEIEKARVVAERALKTISFREEQEKLNVW--VALLNLENMYGTEESLVKAFERAVQYNE---------PLKVYQQLADIYVKSEKFKQAEDLYNTMLKRFRQEKSVWIKFATFLLKQGQGDG--THRLLQRALKSLPEKDHVDVISKFAQLEFQLGDSERAKALFESTLSSYPKRTDLWSVYIDMMVKHGSQREVRDI 1432
BLAST of Programmed cell death 11 vs. Ensembl Mouse
Match: Pdcd11 (programmed cell death 11 [Source:MGI Symbol;Acc:MGI:1341788]) HSP 1 Score: 161.384 bits (407), Expect = 4.387e-39 Identity = 111/393 (28.24%), Postives = 201/393 (51.15%), Query Frame = 3
Query: 987 GSNVIVRYLDYNLIDNVIHATTLNSLLAQSYFSIHQAKLGEIIKGKVLSFSKHGFTVKISSNLTGLIPIPHLSDKPMSNAQKLLAPGDQVQCRVFHIDLLENRLLLTIKKSLMTSTLPIISGISDLQTGMILCGFVAKIFDFGLVVIMFNNVKGWVPIGRVPESKRKSLRVAYYVGKPVEVKVIRWEVATNKIELSLK--EESTIDEEVIE--KNPVNDLEIGDIYEAVITKARVDGFNVRLCPSNKVAFLPFIHLSDSREHRKLFEAHYRMSEKDQLKXXXXXXXXXXXXXXXSKKKSLIEAAVKNEVVKSNNSLTINSQWIGWVIKNESFGLLVELPSGVKGLVRNKDISDILPLSGQSRDLFEIGDTVMAKIIELDPLNLNRILFTLKMS 2153
GS R +DY+ +D + + S++A + H K+G ++KG VL+ G VK+ + GL+P HL+D M N +K +PGD+V+CRV D +L++T+KK+L+TS L +I+ + G+ G + ++ D+G +V +N+V+G VP + +Y G+ V+V V+ E + ++ LS + +S + +E + + IG + + + + G V + P N AFLP HLSD + L H+ + D L V+ ++ ++++ +K +L+ + KS + + IG+V + +G+ V+ PSG+ GL +SD ++ S E G TV+AK+ +D + R+L +L++S
Sbjct: 414 GSTHKCRIIDYSQMDELALLSLRKSIIAAPFLRYHDIKIGTVVKGTVLAIKPFGILVKVGEQIKGLVPSMHLADIMMKNPEKKYSPGDEVKCRVLLCDPEAKKLIMTLKKTLVTSKLSLITCYEGAKPGLQTHGVIIRVKDYGCIVKFYNDVQGLVPKHELSTQHIPDPETVFYTGQVVKVAVLSCEPSKERMLLSFRLLSDSRPKDPGVESSQKKTGAVRIGQLVDVKVLEKTKTGLEVAILPHNTPAFLPTPHLSDHAANGPLL--HHWLQTGDTLH-RVLCLSQSERHILLCRKPALVSTVEGGQDPKSLSEIQPGMLLIGFVKCIKEYGVFVQFPSGLSGLSPKTIMSDKF-VTTPSEHFVE-GQTVVAKVTNVDE-SKQRMLLSLRLS 800 HSP 2 Score: 82.0333 bits (201), Expect = 5.733e-15 Identity = 44/154 (28.57%), Postives = 84/154 (54.55%), Query Frame = 3
Query: 66 LLGRIKEIHEFKLIISLPHNKSGVCRIANISEEYNKLINEFNEDKSIMNEVARLNQLFSKGQIVQVKLTK----NSSNKKNELSMIPSEINCNINANRLKQGIKLQVAIKSREDKGYILETGIGGINSFLPFTECS--------NAEYKTGKML 491
+LG +KE+ E +L++SLP+ G ++ + + Y + +NE + + ++ RL +LFS G +V+ ++ S K +LS+ P +N ++A+ L+ G+ L + S ED GY+++ G+GG +FL + A++K G+ L
Sbjct: 86 ILGCVKEVSELELVVSLPNGLQGFVQVTEVCDAYTQKLNEQVAQEEPLEDLLRLPELFSPGMLVRCVVSSLDVTESGKKSVKLSVNPKRVNKVLSADALRPGMLLTGTVSSLEDHGYLVDIGVGGTRAFLSLKKAQEYIRQKNKGAKFKVGQYL 239 HSP 3 Score: 66.2402 bits (160), Expect = 3.936e-10 Identity = 43/206 (20.87%), Postives = 95/206 (46.12%), Query Frame = 3
Query: 3756 KNPTTETEFELLIFNHPHDSNAWIKFMNFYLENDKNIDKARSIAERAMKMLLSNDIENRFQLMKKYMLLEIDELVAKKDDVSYDDQLIRFRELCQRAMT-QKAKQMYIHVCKNLINAKLFDLAEELSKRFIKDFPNDSVSWFHLFLIRFSQKKYLVVRETLVNAQRSLSVADFRDLTIRVAQAEIEQGDVSRGVQSLVDIFQNRPK 4370
+ P + +F+ L+ + P+ S W+++M F+L+ + I+KAR++AERA+K + + + + + LL ++ + ++ ++ ++ +RA+ + ++++H+ ++ + A EL R +K F + W + + L A L + D+ ++ AQ E + GDV R + PK
Sbjct: 1591 RQPESADDFDRLVLSSPNSSILWLQYMAFHLQATE-IEKARAVAERALKTISFREEQEKLNVW--VALLNLENMYGSQESLT---------KVFERAVQYNEPLKVFLHLADIYTKSEKYKEAGELYNRMLKRFRQEKAVWIKYGAFVLGRSQAGASHRVLQRALECLPAKEHVDVIVKFAQLEFQLGDVERAKAIFENTLSTYPK 1784
BLAST of Programmed cell death 11 vs. UniProt/SwissProt
Match: sp|A7MB10|RRP5_BOVIN (Protein RRP5 homolog OS=Bos taurus OX=9913 GN=PDCD11 PE=2 SV=1) HSP 1 Score: 226.098 bits (575), Expect = 4.006e-58 Identity = 215/850 (25.29%), Postives = 396/850 (46.59%), Query Frame = 3
Query: 66 LLGRIKEIHEFKLIISLPHNKSGVCRIANISEEYNKLINEFNEDKSIMNEVARLNQLFSKGQIVQVKL----TKNSSNKKNELSMIPSEINCNINANRLKQGIKLQVAIKSREDKGYILETGIGGINSFLPFTECS--------NAEYKTGKMLEVFPVITPEKKSR--VTNFTTDIQKRNLVHSSFDPCDFDVILPGMLIKTYLKLSIDGSLEGKFHGFPVCVQPIHHKITDQIST-----ELTMCVIGIDLSLKQLDCSLLSHLKPPFKGSTDLLDVCIG-----------YSEKNCTVTKRDKTKIVISIPDKKYVTGFIAKGHIDPKLQKTDIGSNVIVRYLDYNLIDNVIHATTLNSLLAQSYFSIHQAKLGEIIKGKVLSFSKHGFTVKISSNLTGLIPIPHLSDKPMSNAQKLLAPGDQVQCRVFHIDLLENRLLLTIKKSLMTSTLPIISGISDLQTGMILCGFVAKIFDFGLVVIMFNNVKGWVPIGRVPESKRKSLRVAYYVGKPVEVKVIRWEVATNKIELSLKEESTIDEE-----VIEKNPVNDLEIGDIYEAVITKARVDGFNVRLCPSNKVAFLPFIHLSDSREHRKLFEAHYRMSEKDQLKXXXXXXXXXXXXXXXSKKKSLIEAAVKNEVVKSNNSLTINSQWIGWVIKNESFGLLVELPSGVKGLVRNKDISDILPLSGQSRDLFEIGDTVMAKIIELDPLNLNRILFTLKMSSTYRASEHLVKSINFLIHHFEERKFLKSTVSCKN------VSKLNLGDLVEVKITKQCEWGYTLTLNNDDSVTGFI---RNEHLPNSPITETSVRNAIIIDIDLKDQAIEVTMVNSYVN 2483
+LG +KE++E +L ISLP+ G ++ I + Y + +NE + + ++ L +LFS G +V+ + T S K LS+ P +N ++A LK G+ L + S ED GY+++ G+ G +FLP + A+ K G+ L +I K SR VT + + + + +LPG+++K ++ L KF F + H + T ++ CV+ + + + SL P + T LL +G + T +D T ++ + +++ +K P+ K G+ R +DY+ +D + + S++ + H K G ++KGKVL+ HG VK+ + GL+P HL+D + N +K GD+V+CRV D +L++T+KK+L+ S LP I+ D + G+ GF+ ++ D+G +V +N+V+G VP + +Y G+ V+V V+ E + ++ LS + S +E +K V+ ++ D+ V+ K + DG V + P N FLP HLSD + L ++ + D L V+ ++V V++ +K +L+ A + KS + + IG+V + +G+ V+ PSG+ GL +SD S + D F G TV+AK+ +D R+L +L++S + S+ L EER+ ++S +S ++ ++++ G +++++ + E G L ++ V G + H + + A+I+++D+ + V++ + VN
Sbjct: 86 ILGCVKEVNELELAISLPNGLQGYVQVTEICDAYTEKLNEQVAQEEPLQDLVGLPELFSPGMLVRCVVSSLDTTKGSKKNVMLSLNPKNVNRVLSAETLKPGMLLTGTVSSLEDHGYLVDIGVSGARAFLPLQKAQEYIRQKNKGAKLKVGQYLNC--LIEEVKGSRGVVTLSIGHSEVSAAIATEEQSWTLNSLLPGLVVKAQVQKVTPLGLTLKFLSFFSGLVDFMHLDPKKAGTYFSNQQVRACVLCVHPRTRAVRLSLRPVFLQPGRPLTRLLCQQLGAVLDDVPVQGFFGSAGATFKLKDGT---LAYARRNHLSN--SKKTFKPEAFKP--GNTHKCRIIDYSQMDELALLSLRTSIIEAQFLWYHDIKPGALVKGKVLTIKPHGMVVKMGKQIRGLVPTMHLADILIKNPEKKYHVGDEVKCRVLLCDPKAKKLMMTLKKTLVESKLPAITCYDDAKPGLQTHGFILRVKDYGCIVKFYNDVQGLVPRHELSAEYVPDPESVFYTGQVVKVVVLNCEPSKERMLLSFRLLSDPKQEGEGQSQKKKKAVSAGQLADV--KVLEKTK-DGLKVAVLPHNIPGFLPTAHLSDHVTNGPLL--YHWLQTGDTLH-RVLCLSVSEERVLLCRKPALVSAVEGGQNPKSFSEIHPGMLLIGFVKNIKDYGVFVQFPSGLSGLAPKAILSDKFVTS--TSDHFVEGQTVVAKVTNVDE-EKQRMLLSLRLSDCT-LGDLATTSLLLLSQCLEERQGVRSLMSNRDSVLIQTLAEMTPGMALDLEVQEVLEDGSVLF--SEGPVPGLVLRASKYHRAGQELEPGQKKKAVILNVDMLKLEVHVSLCHDLVN 914
BLAST of Programmed cell death 11 vs. UniProt/SwissProt
Match: sp|Q14690|RRP5_HUMAN (Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3) HSP 1 Score: 216.853 bits (551), Expect = 2.815e-55 Identity = 192/739 (25.98%), Postives = 339/739 (45.87%), Query Frame = 3
Query: 66 LLGRIKEIHEFKLIISLPHNKSGVCRIANISEEYNKLINEFNEDKSIMNEVARLNQLFSKGQIVQVKLTK----NSSNKKNELSMIPSEINCNINANRLKQGIKLQVAIKSREDKGYILETGIGGINSFLPFTECS--------NAEYKTGKMLEVFPVITPEKKSRVTNFTTDIQKRNLVHSSFDPCDFDVILPGMLIKTYLKLSIDGSLEGKFHGFPVCVQPIHHKITDQISTELT-----MCVIGIDLSLKQLDCSLLSHLKPPFKGSTDLL---------DVCIGYSEKNCTVTKRDKTKIVI-----SIPDKKYVTGFIAKGHIDPKLQKTDIGSNVIVRYLDYNLIDNVIHATTLNSLLAQSYFSIHQAKLGEIIKGKVLSFSKHGFTVKISSNLTGLIPIPHLSDKPMSNAQKLLAPGDQVQCRVFHIDLLENRLLLTIKKSLMTSTLPIISGISDLQTGMILCGFVAKIFDFGLVVIMFNNVKGWVP-----IGRVPESKRKSLRVAYYVGKPVEVKVIRWEVATNKIELSLKEESTIDEEVIEKNPVND-------LEIGDIYEAVITKARVDGFNVRLCPSNKVAFLPFIHLSDSREHRKLFEAHYRMSEKDQLKXXXXXXXXXXXXXXXSKKKSLIEAAVKNEVVKSNNSLTINSQWIGWVIKNESFGLLVELPSGVKGLVRNKDISDILPLSGQSRDLFEIGDTVMAKIIELDPLNLNRILFTLKMS 2153
+LG +KE++E +L+ISLP+ G ++ I + Y K +NE + + ++ L +LFS G +V+ ++ + K +LS+ P +N ++A LK G+ L + S ED GY+++ G+ G +FLP + A+ K G+ L V+ + + + + + +LPG+++K ++ L F F V H + T + C++ + + + SL P + T L DV + K T R K ++ + D K V +P+ K G+ R +DY+ +D + + S++ Y H + G ++KG VL+ +G VK+ + GL+P HL+D M N +K GD+V+CRV D +L++T+KK+L+ S LP+I+ +D + G+ GF+ ++ D+G +V +NNV+G VP +P+ +R +Y G+ V+V V+ E + ++ LS K S D E +K P + IG + + + + DG V + P N AFLP HLSD + L H+ + D L V+ ++ V++ +K +L+ + K+ + + IG+V + +G+ ++ PSG+ GL +SD S + D F G TV AK+ +D R+L +L++S
Sbjct: 86 ILGCVKEVNELELVISLPNGLQGFVQVTEICDAYTKKLNEQVTQEQPLKDLLHLPELFSPGMLVRCVVSSLGITDRGKKSVKLSLNPKNVNRVLSAEALKPGMLLTGTVSSLEDHGYLVDIGVDGTRAFLPLLKAQEYIRQKNKGAKLKVGQYLNCIVEKVKGNGGVVSLSVGHSEVSTAIATEQQSWNLNNLLPGLVVKAQVQKVTPFGLTLNFLTFFTGVVDFMHLDPKKAGTYFSNQAVRACILCVHPRTRVVHLSLRPIFLQPGRPLTRLSCQNLGAVLDDVPVQGFFKKAGATFRLKDGVLAYARLSHLSDSKNV--------FNPEAFKP--GNTHKCRIIDYSQMDELALLSLRTSIIEAQYLRYHDIEPGAVVKGTVLTIKSYGMLVKVGEQMRGLVPPMHLADILMKNPEKKYHIGDEVKCRVLLCDPEAKKLMMTLKKTLIESKLPVITCYADAKPGLQTHGFIIRVKDYGCIVKFYNNVQGLVPKHELSTEYIPDPER-----VFYTGQVVKVVVLNCEPSKERMLLSFKLSS--DPEP-KKEPAGHSQKKGKAINIGQLVDVKVLEKTKDGLEVAVLPHNIRAFLPTSHLSDHVANGPLL--HHWLQAGDILH-RVLCLSQSEGRVLLCRKPALVSTVEGGQDPKNFSEIHPGMLLIGFVKSIKDYGVFIQFPSGLSGLAPKAIMSDKFVTS--TSDHFVEGQTVAAKVTNVDE-EKQRMLLSLRLS 800 HSP 2 Score: 67.781 bits (164), Expect = 9.854e-10 Identity = 48/208 (23.08%), Postives = 98/208 (47.12%), Query Frame = 3
Query: 3756 KNPTTETEFELLIFNHPHDSNAWIKFMNFYLENDKNIDKARSIAERAMKMLLSNDIENRFQLMKKYMLLEIDELVAKKDDVSYDDQLIRFRELCQRAMT-QKAKQMYIHVCKNLINAKLFDLAEELSKRFIKDFPNDSVSW--FHLFLIRFSQKKYLVVRETLVNAQRSLSVADFRDLTIRVAQAEIEQGDVSRGVQSLVDIFQNRPK 4370
+ P + +F+ L+ + P+ S W+++M F+L+ + I+KAR++AERA+K + + + + + LL ++ + ++ ++ ++ +RA+ + ++++H+ ++ F A EL R +K F + W + FL+R SQ L A L + D+ + AQ E + GD R + PK
Sbjct: 1600 RQPESADDFDRLVLSSPNSSILWLQYMAFHLQATE-IEKARAVAERALKTISFREEQEKLNVW--VALLNLENMYGSQESLT---------KVFERAVQYNEPLKVFLHLADIYAKSEKFQEAGELYNRMLKRFRQEKAVWIKYGAFLLRRSQAA--ASHRVLQRALECLPSKEHVDVIAKFAQLEFQLGDAERAKAIFENTLSTYPK 1793
BLAST of Programmed cell death 11 vs. UniProt/SwissProt
Match: sp|F4J8K6|RRP5_ARATH (rRNA biogenesis protein RRP5 OS=Arabidopsis thaliana OX=3702 GN=RRP5 PE=2 SV=2) HSP 1 Score: 189.119 bits (479), Expect = 1.004e-46 Identity = 222/880 (25.23%), Postives = 400/880 (45.45%), Query Frame = 3
Query: 66 LLGRIKEIHEFKLIISLPHNKSGVCRIANISEEYNKLINEFNEDKSIMNEVARLNQLFSKGQIVQVKL------TKNSSNKKNELSMIPSEINCNINANRLKQGIKLQVAIKSREDKGYILETGIGGINSFLPFTECSNAE--YKTGKMLEVFPVITPEKKSRVTNFTTDIQKRNLVHSSFDP-----C--------DFDVILPGMLIKTYLKLSIDGSLEGKFHG-FPVCVQPIHHK-------ITDQISTELTMC--VIGIDLSLKQLDCSLLSHL----KPPFK-GSTDLLDVCIGYSEKNCTVTKRDKTKIVISIPDK-----KYVTGFIAKGHIDPKLQKT-DIGSNVIVRYLDYNLIDNVIHATTLNSLLAQSYFSIHQAKLGEIIKGKVLSFSKHGFTVKISSNLTGLIPIPHLSDKPMSNAQKLLAPGDQVQCRVFHIDLLENRLLLTIKKSLMTSTLPIISGISDLQTGMILCGFVAKIFDFGLVVIMFNNVKGWVP---IGRVPESKRKSLRVAYYVGKPVEVKVIRWEVATNKIELSLK-EESTIDEEVIEKNPVNDLEIGDIYEAVITKARVDGFNVRLCPSNKV-AFLPFIHLSDSREHRKLFEAHYRMS-EKDQLKXXXXXXXXXXXXXXXSKKKSLIEAAVKNEVVKSNNSLTINSQWIGWVIKNESFGLLVELPSGVKGLV-RNKDISDILPLSGQSRDLFEIGDTVMAKIIELDPLNLNRILFTLKMSSTYRASEHLVKSINFL---IHHFEERKFLKSTVSCKNVSKLNLGDLVEVKITKQCEWGYTLTLNNDDSVTGFIRNEHLPNSPITETSVRNAIIIDIDLKDQAIEVTMVNSYVNALSHRRNDCTRIEVDQNIASDV 2549
LLG + E+++ ++ISLP G+ R + +S+ ++ I + +E L +FS GQ+V + K + +K LS+ S ++ + + + G+ +KS ED G IL G+ I F+ ++ N E KTG++++ VT D R +VH S DP C FD+++PGM++ ++ ++ + F F V H K D+ + T+ ++ ID S + + +L H+ PP S D+ D V + DK+ +++ +P K YV+ + A G KL+K G+++ VR L ++ + T S F+ K G + K KV+S G V+ S L + P+ H+S+ ++ +K G ++ RV + R+ +T KK+L+ S LPI+S +D G++ G++ KI G V +N V+G+VP +G P S S+ ++VG+ V+ +V T +I LS + S++ E+ + +++G I +I VR+ + V + HL+D E KL + R E D+L +V+++ N+ +S K SLI+ A E+ N L NS G+V G V + G R+K I D P + S F +G +V A I++++ +RI +LK SS V+ + I + KS C V K ++G L++ I +Q + G + +N ++V GFI H+ + + SV NA+++DI ++ +++++ +N L+ ++ ++ + + I+ ++
Sbjct: 131 LLGVVTEVNQKDIVISLPGGLRGLVRASEVSDFTDRGIED--------DENELLGDIFSVGQLVPCIVLELDDDKKEAGKRKIWLSLRLSLLHKGFSFDSFQLGMVFSANVKSIEDHGSILHFGLPSITGFIEISDDGNQESGMKTGQLIQ----------GVVTKIDRD---RKIVHLSSDPDSVAKCLTKDLSGMSFDLLIPGMMVNARVQSVLENGILFDFLTYFNGTVDLFHLKNPLSNKSWKDEYNQNKTVNARILFIDPSSRAVGLTLSPHVVCNKAPPLHVFSGDIFD--------EAKVVRIDKSGLLLELPSKPTPTPAYVSTYDAAGDEVTKLEKKFKEGNHIRVRVLGLKQMEGLAVGTLKESAFEGPVFTHSDVKPGMVTKAKVISVDTFGAIVQFSGGLKAMCPLRHMSEFEVTKPRKKFKVGAELVFRV--LGCKSKRITVTYKKTLVKSKLPILSSYTDATEGLVTHGWITKIEKHGCFVRFYNGVQGFVPRFELGLEPGSDPDSV---FHVGEVVKCRVTSAVHGTQRITLSFMIKPSSVSED-------DSIKLGSIVSGIIDTITSQAVIVRVKSKSVVKGTISAEHLADHHEQAKLIMSLLRPGYELDKL----LVLDIEGNNMALSSKYSLIKLA--EELPSDFNQLQPNSVVHGYVCNLIENGCFVRFLGRLTGFAPRSKAIDD--PKADVSESFF-VGQSVRANIVDVNQ-EKSRITLSLKQSSCASVDASFVQEYFLMDEKISDLQSSDITKS--DCSWVEKFSIGSLIKGTIQEQNDLGVVVNFDNINNVLGFIPQHHMGGATLVPGSVVNAVVLDISRAERLVDLSLRPELLNNLTKEVSNSSKKKRKRGISKEL 957 HSP 2 Score: 55.0694 bits (131), Expect = 7.742e-6 Identity = 40/139 (28.78%), Postives = 64/139 (46.04%), Query Frame = 3
Query: 3762 PTTETEFELLIFNHPHDSNAWIKFMNFYLENDKNIDKARSIAERAMKMLLSNDIENRFQLMKKYMLLEIDELVAKKDDVSYDDQLIRFRELCQRAMTQKAKQMYIHVCKNLINAKLFDLAEELSKRFIKDFPNDSVSWF 4178
P EFE L+ + P+ S WIK+M F L + +I+KARSIAERA++ + + E + + Y LE + + S R R+ C K++Y+ + + + LA++L IK F W
Sbjct: 1654 PENADEFEKLVRSSPNSSFVWIKYMAFML-SLADIEKARSIAERALRTINIREEEEKLNIWVAYFNLENEH--GNPPEESVKKVFERARQYCD------PKKVYLALLGVYERTEQYKLADKLLDEMIKKFKQSCKIWL 1783
BLAST of Programmed cell death 11 vs. UniProt/SwissProt
Match: sp|Q6NS46|RRP5_MOUSE (Protein RRP5 homolog OS=Mus musculus OX=10090 GN=Pdcd11 PE=1 SV=2) HSP 1 Score: 161.384 bits (407), Expect = 3.069e-38 Identity = 111/393 (28.24%), Postives = 201/393 (51.15%), Query Frame = 3
Query: 987 GSNVIVRYLDYNLIDNVIHATTLNSLLAQSYFSIHQAKLGEIIKGKVLSFSKHGFTVKISSNLTGLIPIPHLSDKPMSNAQKLLAPGDQVQCRVFHIDLLENRLLLTIKKSLMTSTLPIISGISDLQTGMILCGFVAKIFDFGLVVIMFNNVKGWVPIGRVPESKRKSLRVAYYVGKPVEVKVIRWEVATNKIELSLK--EESTIDEEVIE--KNPVNDLEIGDIYEAVITKARVDGFNVRLCPSNKVAFLPFIHLSDSREHRKLFEAHYRMSEKDQLKXXXXXXXXXXXXXXXSKKKSLIEAAVKNEVVKSNNSLTINSQWIGWVIKNESFGLLVELPSGVKGLVRNKDISDILPLSGQSRDLFEIGDTVMAKIIELDPLNLNRILFTLKMS 2153
GS R +DY+ +D + + S++A + H K+G ++KG VL+ G VK+ + GL+P HL+D M N +K +PGD+V+CRV D +L++T+KK+L+TS L +I+ + G+ G + ++ D+G +V +N+V+G VP + +Y G+ V+V V+ E + ++ LS + +S + +E + + IG + + + + G V + P N AFLP HLSD + L H+ + D L V+ ++ ++++ +K +L+ + KS + + IG+V + +G+ V+ PSG+ GL +SD ++ S E G TV+AK+ +D + R+L +L++S
Sbjct: 414 GSTHKCRIIDYSQMDELALLSLRKSIIAAPFLRYHDIKIGTVVKGTVLAIKPFGILVKVGEQIKGLVPSMHLADIMMKNPEKKYSPGDEVKCRVLLCDPEAKKLIMTLKKTLVTSKLSLITCYEGAKPGLQTHGVIIRVKDYGCIVKFYNDVQGLVPKHELSTQHIPDPETVFYTGQVVKVAVLSCEPSKERMLLSFRLLSDSRPKDPGVESSQKKTGAVRIGQLVDVKVLEKTKTGLEVAILPHNTPAFLPTPHLSDHAANGPLL--HHWLQTGDTLH-RVLCLSQSERHILLCRKPALVSTVEGGQDPKSLSEIQPGMLLIGFVKCIKEYGVFVQFPSGLSGLSPKTIMSDKF-VTTPSEHFVE-GQTVVAKVTNVDE-SKQRMLLSLRLS 800 HSP 2 Score: 82.0333 bits (201), Expect = 4.010e-14 Identity = 44/154 (28.57%), Postives = 84/154 (54.55%), Query Frame = 3
Query: 66 LLGRIKEIHEFKLIISLPHNKSGVCRIANISEEYNKLINEFNEDKSIMNEVARLNQLFSKGQIVQVKLTK----NSSNKKNELSMIPSEINCNINANRLKQGIKLQVAIKSREDKGYILETGIGGINSFLPFTECS--------NAEYKTGKML 491
+LG +KE+ E +L++SLP+ G ++ + + Y + +NE + + ++ RL +LFS G +V+ ++ S K +LS+ P +N ++A+ L+ G+ L + S ED GY+++ G+GG +FL + A++K G+ L
Sbjct: 86 ILGCVKEVSELELVVSLPNGLQGFVQVTEVCDAYTQKLNEQVAQEEPLEDLLRLPELFSPGMLVRCVVSSLDVTESGKKSVKLSVNPKRVNKVLSADALRPGMLLTGTVSSLEDHGYLVDIGVGGTRAFLSLKKAQEYIRQKNKGAKFKVGQYL 239 HSP 3 Score: 66.2402 bits (160), Expect = 2.753e-9 Identity = 43/206 (20.87%), Postives = 95/206 (46.12%), Query Frame = 3
Query: 3756 KNPTTETEFELLIFNHPHDSNAWIKFMNFYLENDKNIDKARSIAERAMKMLLSNDIENRFQLMKKYMLLEIDELVAKKDDVSYDDQLIRFRELCQRAMT-QKAKQMYIHVCKNLINAKLFDLAEELSKRFIKDFPNDSVSWFHLFLIRFSQKKYLVVRETLVNAQRSLSVADFRDLTIRVAQAEIEQGDVSRGVQSLVDIFQNRPK 4370
+ P + +F+ L+ + P+ S W+++M F+L+ + I+KAR++AERA+K + + + + + LL ++ + ++ ++ ++ +RA+ + ++++H+ ++ + A EL R +K F + W + + L A L + D+ ++ AQ E + GDV R + PK
Sbjct: 1591 RQPESADDFDRLVLSSPNSSILWLQYMAFHLQATE-IEKARAVAERALKTISFREEQEKLNVW--VALLNLENMYGSQESLT---------KVFERAVQYNEPLKVFLHLADIYTKSEKYKEAGELYNRMLKRFRQEKAVWIKYGAFVLGRSQAGASHRVLQRALECLPAKEHVDVIVKFAQLEFQLGDVERAKAIFENTLSTYPK 1784
BLAST of Programmed cell death 11 vs. UniProt/SwissProt
Match: sp|O74835|RRP5_SCHPO (rRNA biogenesis protein rrp5 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=rrp5 PE=1 SV=1) HSP 1 Score: 158.303 bits (399), Expect = 2.389e-37 Identity = 170/711 (23.91%), Postives = 310/711 (43.60%), Query Frame = 3
Query: 60 SILLGRIKEIHEFKLIISLPHNKSGVCRIANISEEYNKLI---------NEFNEDKSIMNEVARLNQLFSKGQIVQVKLTKNSSNKKN-------ELSMIPSEINCNI-NANRLKQGIKLQVAIKSREDKGYILETGIGGINSFLPFTECSNAEYKTGKMLEVFPVITPEKKSRVTNFTTDIQKRNLVHSSFDPCDFDVILPGMLIKTYLKLSIDGSLEGKFHGFPVCVQPIHH-------------KITDQISTELTMCVIGIDLSLKQLDCSLLSHL-----KPPFKGSTDLLDVCIGYSEKNCTVTKRDKTKIV---ISIPDKKYVTGF--IAK------GHIDPKLQKTDIGSNVIVRYLDYNLIDNVIHATTLNSLLAQSYFSIHQAKLGEIIKGKVLSFSKHGFTVKISSNLTGLIPIPHLSDKPMSNAQKLLAPGDQVQCRVFHIDLLENRLLLTIKKSLMTSTLPIISGISDLQTGMILCGFVAKIFDFGLVVIMFNNVKGWVPIGRVPESKRKSLRVAYYVGKPVEVKVIRWEVATNKIELSLKEESTIDEEVIEKNPVNDLEIGDIYEAVITKARVDGFNVRLCPSNKV-AFLPFIHLSD------SREHRKLFEAHYRMSEKDQLKXXXXXXXXXXXXXXXSKKKSLIEAAVKNEVVKSNNSLTINSQWIGWVIKNESFGLLVELPSGVKGLVRNKDISD 2033
S++LG+I +I+ L +SLP+ +G I NIS++ + + N E++ +N++ L L+ GQ V+V +T S ELS+ P + N + A G +Q + S ED G + + GI FL ++ + G+ L + VI+ E + + T K V S ILPG I + + + K+ G I+H ++ + + + G ++ S L H+ P D LD IG+ VT + V + +P+ ++GF I++ I P + S R ++Y+ +DN+ + S+L Q + I ++G+ + G + G V IS + GL+P H++D + ++ G V+CRV ++L R+LLT+KKSL+ + LP+I G G +A+IF+ G +V +N+V+ ++P+ + E+ + R + VG+ + V ++ + K+ + +E+S D + +E+ +++ G + ++ + D V L +KV + L D S+ KL A +++E L+ + + +S KKSL+EAA +N + + L ++ G+V +FG+ VE G+ LV IS+
Sbjct: 110 SLILGQIAQINTLDLAVSLPNCLTGYVPITNISDKLSDRLDSIDNHAEDNAATEEEDGLNQIPDLMDLYKVGQWVRVSVTALGSENTTKTGKRHIELSLKPQDANGSAPEAADFVAGSMIQAVVSSIEDHGIVFDIGINNYTGFLSKKHINDFPFVEGQSL-LCSVISKEDRIFHLSLTATSTKALEVMPSVQ-----AILPGDYINVLVTDIKESGVIAKYMGVVDVTSDIYHSSPVKGEDLEDKFQLAKSVPARVLFVIPG---DPPKIAVSFLPHVLTFNFATPNTPHPDQLD--IGFIVNAAKVTYVSSSLGVFCDVGVPE---ISGFAHISRLSDKKVAGISPNSGPYKVDSTHEARIINYSYVDNLYILSFQQSVLNQQFLRIEDIEVGQFVDGTIAKLIPQGIVVTISEGINGLVPSTHMADIALQFPERRFKVGSSVKCRVLSTNVLRKRVLLTLKKSLLNTDLPLIYDYEQATPGTQTVGTLARIFEDGAIVEFYNSVRAFLPVSEMSEAYIRDAREHFKVGQTLSVTIVSCDPENRKMRVGCREQS-WDAKRLER--FENIKAGSVLSGIVLQKTEDSVIVDL--GDKVTGVITLGQLCDGDLNKCSKVMNKL-RASTKLAEVLVLR-----KDTSKKLISLSLKKSLVEAAKENRMPINITDLKEGIKYFGFVRNATTFGVFVEFCDGLVALVPKAYISE 795 HSP 2 Score: 54.6842 bits (130), Expect = 8.277e-6 Identity = 56/225 (24.89%), Postives = 94/225 (41.78%), Query Frame = 3
Query: 1098 KLGEIIKGKVLSFSKHGFTVKISSNLTGLIPIPHLSDKPMSNAQKLL----APGDQVQCRVFHIDLLENRLLLTIKKSLMTST----LPIISGISDLQTGMILCGFVAKIFDFGLVVIMFNNVKGWVPIGRVPESKRKSLRVAYYVGKPVEVKVIRWEVATNKIELSLKEESTIDEEVIE--------KNPVN-------DLEIGDIYEAVITKARVDGFNVRLC 1703
K G ++ G VL ++ V + +TG+I + L D ++ K++ A + V D + + L++KKSL+ + +PI I+DL+ G+ GFV FG+ V + + VP + E Y + V + E++ K +S K + E+ +E NPV+ D G I AV+T A+ NV L
Sbjct: 664 KAGSVLSGIVLQKTEDSVIVDLGDKVTGVITLGQLCDGDLNKCSKVMNKLRASTKLAEVLVLRKDTSKKLISLSLKKSLVEAAKENRMPI--NITDLKEGIKYFGFVRNATTFGVFVEFCDGLVALVPKAYISEEYVPVPSAVYKPQQSVTCVCLSVELSQEKAFMSFKPLAQKQEKAVEFMESKYDIDNPVDETIKKTYDYVAGKITWAVVTSAKASQLNVDLA 886
BLAST of Programmed cell death 11 vs. TrEMBL
Match: A0A504X973 (Uncharacterized protein OS=Fasciola gigantica OX=46835 GN=FGIG_00310 PE=4 SV=1) HSP 1 Score: 328.561 bits (841), Expect = 1.127e-87 Identity = 293/1170 (25.04%), Postives = 525/1170 (44.87%), Query Frame = 3
Query: 48 MENDSILLGRIKEIHEFKLIISLPHNKSGVCRIANISEEYNKLINEFNEDKSIMNEVARLNQLFSKGQIVQVKLTKNS-----SNKKNELSMIPSEINCN---INANRLKQGIKLQV----AIKSREDKGYILETGIGGINSFLPFTECSNAEYKTGKMLEVFPV------ITPEKKSRVTNFTTDIQKRNLVHSSFDPCDFDVILPGMLIKTYLKLSIDGSLEGKFHGFPVCVQPIHHKITDQ---ISTELTMCVIGIDLSLKQLDCSLLSHLKPP----FKGSTDLLDVCIGYSEKNCTVTKRDKTKIVISIPDKKYVTGFIAKGHIDPKLQ------KTDIGSNVIVRYLDYNLIDNVIHATTLNSLLAQSYFSIHQAKLGEIIKGKVLSFSKHGFTVKISSNLTGLIPIPHLSDKPMSNAQKLLAPGDQVQCRVFHIDLLENRLLLTIKKSLMTSTLPIIS------GISDLQ-----TGMILCGFVAKIFDFGLVVIMFNNVKGWVPIGRVPESKRKSLRVAYYVGKPVEVKVIRW----EVATNKIELSLKEESTIDEEVIEKNPVN----DLEIGDIYEAVITKARVDGFNVRLC----PSN--------KVAFLPFIHLSDSREHRKLF-------EAHYRMSEKDQLKXXXXXXXXXXXXXXXSKKKSLIEAAVKNEVVKSNNS----------------LTINSQWIGWVIKNESFGLLVELPSGVKGLVRNKDISDI-LPLSGQSRDLFEIGDTVMAKIIELDPLNLNRILFTLKMSSTYRASEHLVK-SINFLIHHFEERKFLKSTVSCKNVSKLNLGDLVEVKIT------------KQCEW---GYTLTLNNDDS-VTGFIRNEHLPNSPITETSVRNAIIIDIDLKDQAIEVTMVNSYVNALSHRRND---CTRIEVDQNIASDVLGF-NKDFVVSIFQGHAGGNLVFIPTKRFWNDIAKESMWLVKQRNNTILKTVLENE-----VFIGSLEINEPINC--DDAQV--------VNIDIPFKNLARKIK----AIKDKTYRTYFHSVSKTKVYFYISKLQRGCCKLLNYSTSIEEIQQLIEKTPQRYSIMNKSVKITDAKKGHGIASG---------HFLEKDVLEVGDTVCCKVTAIISKNKYILKMPFDNIG 3152
ME DS++LGRIK + +F L + LPH + G I ++S++Y +++ E VA L+QLF GQ V+ + N+ + +P+E++ N +N L++ I L A+ + ED G+ ++ G+ + FLP + + G+++ V P+ K RV + + V + F +LPG+ ++ + I +L KF + + V H+ ++ + E+ +C++ +D KQL SLL HL PP + S + IG + VT+ DK + + + + + G I K H+ KL+ K +G + R +DY+L++NV AT LL Y SI + G+ + ++ F+K G V++ L GLIP HL+D P+ N K G ++ CRV +D N+++LT K+ L+ +T PII ++D + + FVAKI + GL++I N ++ W+P S+ +L Y+ G+ + V+++R +T K EL + + EE ++K+ +G I++A + K G V L P N V FL F L+D + L + R+ VVVI V+VS K +L+ AA + + S+ + L + SQW V + +G+ V PS ++GL + +SD +P DLF G TV+AK++E+ P R L +L+M TY A EH V +I L E++++ S +S +GDLV +IT KQ + ++ + N +S V+ + E+ + +A++ +D +E+ + + +N+++HR ++ CT + + Q ++ + KD V F+GHA G +P +R +ND+ + W++ QRN L+T + + ++ +L I +P+ D V V P +LA + + + F V + + C+ +N+ + + ++ ++ P + ++++ + A G FLEK ++V D VC ++ +S++ + L++P D +G
Sbjct: 1 MEADSLVLGRIKSVSKFYLELCLPHGRVGRVNIYDVSDKYTEILKELISSSDSNKNVASLDQLFKVGQFVRGCMKNNAFDAGGGDHAQSKGWVPTEVSLNPKLVNKGLLRKRISLNCWLVGAVVTEEDHGFTIDIGVSDMECFLPKSHV-QGDVNLGQLITVAPISSDSMNFAAAKDVRVLTVSALREDIESVMNPLQSIHFCTLLPGVWLRGTINGKIKSTLVVKFCDYLISVSRAHYMGDNEDYAQNKEVVVCLLVVDPGTKQLTGSLLPHLLPPSCPEYVPSLSCDTISIGSKFPSAVVTRVDKRTVHVRLESEDGIQGVIRKTHVPEKLKCDNLKAKFSVGQKINCRVIDYDLLENVALATMKKKLLRLPYLSISEVSPGDKVNVEISRFTKTGIVVRVEERLNGLIPFLHLADMPIKNPNKKFTGGQKLVCRVLTVDKTSNKMILTAKRGLVEATCPIIGSKEMVEALTDAKFLRNLGDQLYAAFVAKICEHGLLLIGLNGMRAWLPKMESGLSEDDALEATYFRGQVLRVRILRRFKPSTDSTQKSELLVSLKLKESEETVQKDRTPQQKCSFSVGQIFDAKVHKVVKSGIIVDLLSATDPENGKSGLQTVGVGFLRFDQLTDHETNVPLLTNCLSNAKPGKRLELDGNTARQVVVICKTAKAVLVSAKSTLVRAAKECQQTVSDKTDGSVCNSTGFLREFSELRVGSQWFASVQNHVDYGIFVNFPSAIRGLAPVRLLSDTHIPPKVSMMDLFPPGATVIAKVVEVAPSEKRRCLVSLRMMDTYVAEEHYVNGAIQSLHSWMTEQEWISR--SQNALSMYRIGDLVSFQITDSDALIAVGEACKQTQGQMASHSASRKNKNSWVSALVYRENAEGIECRPGELYSAVVTFVDFAASRLELALSSWLLNSINHRDDEEDSCT-LRLGQKVSCVTVAVRQKDVAVVAFRGHAAGRFGLVPARRTFNDVIGGNAWVLGQRNQVTLRTSFKQQDPSPILYFCTLSIYDPVTAAVDSHTVRSKHGFALVESSAPHWSLAPGTELNGLRLNHIVGQIIFLEVPSSSNHLVF-------CRAINWDRTSKAVRSFLKHPPALGTEIDRTATVLLAASSDTGGRGTLHSRLPEVSFLEKTDVDVDDVVCGRLLR-VSRDHWTLRLPGDTVG 1158 HSP 2 Score: 87.4261 bits (215), Expect = 2.641e-13 Identity = 67/263 (25.48%), Postives = 110/263 (41.83%), Query Frame = 3
Query: 3690 TNVKKEILIRTAEKRRETGESLKNPTTETEFELLIFNHPHDSNAWIKFMNFYLENDKN---IDKARSIAERAMKMLLS-NDIENRFQLMKK------YMLLEIDEL--------------VAKKDDVSYDDQLIRFRELCQRAMTQKAKQMYIHVCKNLINAKLFDLAEELSKRFIKDFPNDSVSWFHLFLIRFSQKKYLVVRETLVNAQRSLSVADFRDLTIRVAQAEIEQGDVSRGVQSLVDIFQNRPKDISLKNRIVSIL 4406
T +K IL + E L P+T EFEL + N P +S W +M L + + +AR+IAER ++ + S D+E Q M++ Y+++E EL + + +DQ R ++ R + + + + + F+ AE+L++R IK P D W L +RF + RE NA + + L A+ E E GDV R + L + PK + ++ IL
Sbjct: 1478 TEQRKAILAALTTAQPCLPEGLMRPSTTEEFELTVRNAPSNSACWTAYMTHILAGNSGPTALSEARTIAERGLRAIGSMPDLEPGEQEMQQARLLLFYLIMEAKELERCTQQKETHTLYHLGTDPALELNDQANRVSQVLSRLVNLDQAEFTRRAIETMADIGQFERAEDLARRLIKSCPLDVDRWLSLIKVRFRAGRVAAAREAQRNAVGIVRSSQLPRLLTSAARLEFEFGDVDRSLSLLREQLSAHPKQHLIYEELIKIL 1740
BLAST of Programmed cell death 11 vs. TrEMBL
Match: A0A1S3JHX3 (protein RRP5 homolog isoform X1 OS=Lingula unguis OX=7574 GN=LOC106173061 PE=4 SV=1) HSP 1 Score: 308.145 bits (788), Expect = 3.771e-81 Identity = 253/940 (26.91%), Postives = 455/940 (48.40%), Query Frame = 3
Query: 63 ILLGRIKEIHEFKLIISLPHNKSGVCRIANISEEYNKLINEF--NEDKSIMNEVARLNQLFSKGQIVQVKLT-----KNSSNKKNELSMIPSEINCNINANRLKQGIKLQVAIKSREDKGYILETGIGGINSFLPFTECSNAEYKTGKMLEVFPVITPEKK-------------SRVTNFTTDIQKRNLVHSSFDPCDFDVILPGMLIKTYLKLSIDGSLEGKFHGFPVCVQPIH---HKITDQISTELTMCVIGIDLSLKQLDCSLLSHLKPPFKGSTDLL-DVCIGYSEKNCTVTKRDKTKIVISIPDKKYVTGFIAKGHIDPK-----LQKTDIGSNVIVRYLDYNLIDNVIHATTLNSLLAQSYFSIHQAKLGEIIKGKVLSFSKHGFTVKISSNLTGLIPIPHLSDKPMSNAQKLLAPGDQVQCRVFHIDLLENRLLLTIKKSLMTSTLPIISGISDLQTGMILCGFVAKIFDFGLVVIMFNNVKGWVPIGRVPESKRKSLRVAYYVGKPVEVKVIRWEVATNKIELSLKEESTIDEEVIEKNPVN--------DLEIGDIYEAVITKARVDGFNVRLCPSNKVAFLPFIHLSDSREHRKLFEAHYRMSEKDQLKXXXXXXXXXXXXXXXSKKKSLIEAAVKNEVVKSNNSLTINSQWIGWVIKNESFGLLVELPSGVKGLVRNKDISDILPLSGQSRDLFEIGDTVMAKIIELDPLNLNRILFTLKMSSTYRASEHLVKSINFLIHHFEERKFLKSTVSCK-----NVSKLNLGDLVEVKITKQCEWGYTLTLNNDDSVTGFIRNEHLPNSPITETSVRNAIIIDIDLKDQAIEVTMVNSYVNALSHRR-NDCTRIEVDQNIASDVLGFNKDFVVSIFQGHAGGNLVFIPTKRFWNDIAKESMWLVKQRNNTILKTVLENEVFIGSLEINEPIN 2753
++LG +KEI +++L+++LP G I +IS+ Y KL+ + N D ++ L+ LF+ GQ++ K K + K+ +L++ P E+N ++ A+ LK G+ + ++ S+ED GY+L+ GI G+ +FL + + GK + P + K +R T +++ N D +LPGML+ + + + KF + + H + Q E+ ++ I + K + S+L HLK + S DLL G + V DKTK V + +K VT F ++ K Q GS R LD++ +DN++ + S+L Q + G +++ V K G +VK+S+ + G +P HL D + +K +++CRV ++D + RL+LT K+SL+ S LPII+ S L+TG+ + GF+ KI D G++V ++NNVKG+VP + K +Y+G+ V+ +V+ +E +T+ +V E+ P D EIG + + ITK GF+V L PS AF+P HLSD E+ ++ Y SE + +K + ++ + ++KK S ++AA + ++ + + G + K +G+ V+ + + GL K +SD S L+++G +V+AK+IE+D R L +L+MS Y + I+ L + ER + S + K +S++ +G +V V + + E G L + + G + E++ A+++ ID+ +E+ V A+ H+R N ++++ Q++ DVL DF++ +GHA G L ++P K+ ND ++ + + Q N+ ++K + + + + SL+ +E N
Sbjct: 80 LILGCVKEIQQYELVLNLPSGLKGFVPITSISDTYTKLLQQMVANNDGEKEEDIPSLHDLFTVGQVLCCKCVELVGGKKAGKKRLKLTINPGEVNKSLQASGLKGGMVIPCSVSSKEDHGYVLDVGIKGVQAFLGNKDAAKG---LGKGCVLHPGQHLKCKVKGSSSLGLMSGDTRTIQVTISLKELNDAVVP-DGSTLQNLLPGMLVNAKISKLYESGIGVKFLTYSGIINKSHLMKDPQSFQKQEEVRGTILYIHPTTKSISLSMLPHLKE-VQPSNDLLASFSPGSVIEKAEVLSVDKTKGVY-LRLEKNVTAFAPLKNLSDKEIKDIAQVFRAGSTHRCRVLDHDYMDNIMLVSCKESVLNQKFLGYQDIHPGMVVECNVQGIHKKGVSVKVSNQIRGFVPTIHLFDAALKQPEKKFKESQKMKCRVLNVDPAKQRLILTHKRSLVNSKLPIITQYSQLETGITVDGFIVKIMDAGVLVALYNNVKGFVPKKELSAEKIDYPEKMFYIGQVVKCRVLNC--------FPDEERATLSFKVSERTPFGSKLATVPEDFEIGKLVDCKITKKTDSGFDVALLPSRLRAFIPKAHLSDHMENCEVLWDSY--SEGNVIK--SAMYFNRSSVLTLTKKPSFVQAAKDDNLITEFSKIKPGLLLPGVIHKVMDYGVFVDTCNALIGLAPTKFMSDKRVADASS--LYKVGQSVIAKVIEVDE-EKKRFLLSLRMSDCYHDDTSI--GIDHLEDYLVERDLVLSKLEGKKGQKHRLSEVAVGSVVGVTVAEVTEHGALCNL--ESGLRGVVTYENMIGVTCQPGDHLEAVVLHIDVLASCLELAFNQELVKAIKHKRENKFSQVKPGQHMKCDVLLIKDDFILVSLKGHALGKLGYLPAKKHPNDFLEKHQFSINQTNSVVVKRIYMDHILL-SLQTHEEKN 993 HSP 2 Score: 76.6406 bits (187), Expect = 5.904e-10 Identity = 58/219 (26.48%), Postives = 100/219 (45.66%), Query Frame = 3
Query: 3729 KRRETGESLKNPTTETEFELLIFNHPHDSNAWIKFMNFYLENDKNIDKARSIAERAMKMLLSNDIENRFQLMKKYMLLEIDELVAKKDDVSYDDQLIR-FRELCQRAMTQKAKQMYIHVCKNLINAKLFDLAEELSKRFIKDFPNDSVSWFHLFLIRFSQKKYLVVRETLVNAQRSLSVADFRDLTIRVAQAEIEQGDVSRGVQSLVDIFQNRPKDISL 4382
+ R G+ ++ P + E++ L+ S W+ +M F L+ + IDKAR++AERA+K + + + + + YM LE + +QL + F Q+A K Q I + + ++ +LAE+L + +K F +W F Q + R+ L + +SL D +L + AQ E + G+ RG +I N PK L
Sbjct: 1524 EERMLGQQME-PQSIEEYDRLVLQSSDSSVVWLAYMAFLLKTTE-IDKARAVAERALKTISFREEQEKLNVWVAYMNLE--------NMYGSPEQLNQVFERALQQAEPFKVYQKLIDI---YVRSEKHELAEQLYNKLVKRFSLRKDTWISFGTFYFRQNRAESARKLLQRSLKSLEKKDHIELIAKFAQMEFQHGEAERGKTMFENILSNYPKRTDL 1729
BLAST of Programmed cell death 11 vs. TrEMBL
Match: A0A1S3JGH2 (protein RRP5 homolog isoform X2 OS=Lingula unguis OX=7574 GN=LOC106173061 PE=4 SV=1) HSP 1 Score: 308.145 bits (788), Expect = 3.804e-81 Identity = 253/940 (26.91%), Postives = 455/940 (48.40%), Query Frame = 3
Query: 63 ILLGRIKEIHEFKLIISLPHNKSGVCRIANISEEYNKLINEF--NEDKSIMNEVARLNQLFSKGQIVQVKLT-----KNSSNKKNELSMIPSEINCNINANRLKQGIKLQVAIKSREDKGYILETGIGGINSFLPFTECSNAEYKTGKMLEVFPVITPEKK-------------SRVTNFTTDIQKRNLVHSSFDPCDFDVILPGMLIKTYLKLSIDGSLEGKFHGFPVCVQPIH---HKITDQISTELTMCVIGIDLSLKQLDCSLLSHLKPPFKGSTDLL-DVCIGYSEKNCTVTKRDKTKIVISIPDKKYVTGFIAKGHIDPK-----LQKTDIGSNVIVRYLDYNLIDNVIHATTLNSLLAQSYFSIHQAKLGEIIKGKVLSFSKHGFTVKISSNLTGLIPIPHLSDKPMSNAQKLLAPGDQVQCRVFHIDLLENRLLLTIKKSLMTSTLPIISGISDLQTGMILCGFVAKIFDFGLVVIMFNNVKGWVPIGRVPESKRKSLRVAYYVGKPVEVKVIRWEVATNKIELSLKEESTIDEEVIEKNPVN--------DLEIGDIYEAVITKARVDGFNVRLCPSNKVAFLPFIHLSDSREHRKLFEAHYRMSEKDQLKXXXXXXXXXXXXXXXSKKKSLIEAAVKNEVVKSNNSLTINSQWIGWVIKNESFGLLVELPSGVKGLVRNKDISDILPLSGQSRDLFEIGDTVMAKIIELDPLNLNRILFTLKMSSTYRASEHLVKSINFLIHHFEERKFLKSTVSCK-----NVSKLNLGDLVEVKITKQCEWGYTLTLNNDDSVTGFIRNEHLPNSPITETSVRNAIIIDIDLKDQAIEVTMVNSYVNALSHRR-NDCTRIEVDQNIASDVLGFNKDFVVSIFQGHAGGNLVFIPTKRFWNDIAKESMWLVKQRNNTILKTVLENEVFIGSLEINEPIN 2753
++LG +KEI +++L+++LP G I +IS+ Y KL+ + N D ++ L+ LF+ GQ++ K K + K+ +L++ P E+N ++ A+ LK G+ + ++ S+ED GY+L+ GI G+ +FL + + GK + P + K +R T +++ N D +LPGML+ + + + KF + + H + Q E+ ++ I + K + S+L HLK + S DLL G + V DKTK V + +K VT F ++ K Q GS R LD++ +DN++ + S+L Q + G +++ V K G +VK+S+ + G +P HL D + +K +++CRV ++D + RL+LT K+SL+ S LPII+ S L+TG+ + GF+ KI D G++V ++NNVKG+VP + K +Y+G+ V+ +V+ +E +T+ +V E+ P D EIG + + ITK GF+V L PS AF+P HLSD E+ ++ Y SE + +K + ++ + ++KK S ++AA + ++ + + G + K +G+ V+ + + GL K +SD S L+++G +V+AK+IE+D R L +L+MS Y + I+ L + ER + S + K +S++ +G +V V + + E G L + + G + E++ A+++ ID+ +E+ V A+ H+R N ++++ Q++ DVL DF++ +GHA G L ++P K+ ND ++ + + Q N+ ++K + + + + SL+ +E N
Sbjct: 80 LILGCVKEIQQYELVLNLPSGLKGFVPITSISDTYTKLLQQMVANNDGEKEEDIPSLHDLFTVGQVLCCKCVELVGGKKAGKKRLKLTINPGEVNKSLQASGLKGGMVIPCSVSSKEDHGYVLDVGIKGVQAFLGNKDAAKG---LGKGCVLHPGQHLKCKVKGSSSLGLMSGDTRTIQVTISLKELNDAVVP-DGSTLQNLLPGMLVNAKISKLYESGIGVKFLTYSGIINKSHLMKDPQSFQKQEEVRGTILYIHPTTKSISLSMLPHLKE-VQPSNDLLASFSPGSVIEKAEVLSVDKTKGVY-LRLEKNVTAFAPLKNLSDKEIKDIAQVFRAGSTHRCRVLDHDYMDNIMLVSCKESVLNQKFLGYQDIHPGMVVECNVQGIHKKGVSVKVSNQIRGFVPTIHLFDAALKQPEKKFKESQKMKCRVLNVDPAKQRLILTHKRSLVNSKLPIITQYSQLETGITVDGFIVKIMDAGVLVALYNNVKGFVPKKELSAEKIDYPEKMFYIGQVVKCRVLNC--------FPDEERATLSFKVSERTPFGSKLATVPEDFEIGKLVDCKITKKTDSGFDVALLPSRLRAFIPKAHLSDHMENCEVLWDSY--SEGNVIK--SAMYFNRSSVLTLTKKPSFVQAAKDDNLITEFSKIKPGLLLPGVIHKVMDYGVFVDTCNALIGLAPTKFMSDKRVADASS--LYKVGQSVIAKVIEVDE-EKKRFLLSLRMSDCYHDDTSI--GIDHLEDYLVERDLVLSKLEGKKGQKHRLSEVAVGSVVGVTVAEVTEHGALCNL--ESGLRGVVTYENMIGVTCQPGDHLEAVVLHIDVLASCLELAFNQELVKAIKHKRENKFSQVKPGQHMKCDVLLIKDDFILVSLKGHALGKLGYLPAKKHPNDFLEKHQFSINQTNSVVVKRIYMDHILL-SLQTHEEKN 993 HSP 2 Score: 77.0258 bits (188), Expect = 4.822e-10 Identity = 58/219 (26.48%), Postives = 100/219 (45.66%), Query Frame = 3
Query: 3729 KRRETGESLKNPTTETEFELLIFNHPHDSNAWIKFMNFYLENDKNIDKARSIAERAMKMLLSNDIENRFQLMKKYMLLEIDELVAKKDDVSYDDQLIR-FRELCQRAMTQKAKQMYIHVCKNLINAKLFDLAEELSKRFIKDFPNDSVSWFHLFLIRFSQKKYLVVRETLVNAQRSLSVADFRDLTIRVAQAEIEQGDVSRGVQSLVDIFQNRPKDISL 4382
+ R G+ ++ P + E++ L+ S W+ +M F L+ + IDKAR++AERA+K + + + + + YM LE + +QL + F Q+A K Q I + + ++ +LAE+L + +K F +W F Q + R+ L + +SL D +L + AQ E + G+ RG +I N PK L
Sbjct: 1524 EERMLGQQME-PQSIEEYDRLVLQSSDSSVVWLAYMAFLLKTTE-IDKARAVAERALKTISFREEQEKLNVWVAYMNLE--------NMYGSPEQLNQVFERALQQAEPFKVYQKLIDI---YVRSEKHELAEQLYNKLVKRFSLRKDTWISFGTFYFRQNRAESARKLLQRSLKSLEKKDHVELIAKFAQMEFQHGEAERGKTMFENILSNYPKRTDL 1729
BLAST of Programmed cell death 11 vs. TrEMBL
Match: A0A1S3JGG4 (protein RRP5 homolog isoform X4 OS=Lingula unguis OX=7574 GN=LOC106173061 PE=4 SV=1) HSP 1 Score: 307.76 bits (787), Expect = 4.338e-81 Identity = 253/940 (26.91%), Postives = 456/940 (48.51%), Query Frame = 3
Query: 63 ILLGRIKEIHEFKLIISLPHNKSGVCRIANISEEYNKLINEF--NEDKSIMNEVARLNQLFSKGQIVQVKLT-----KNSSNKKNELSMIPSEINCNINANRLKQGIKLQVAIKSREDKGYILETGIGGINSFLPFTECSNAEYKTGKMLEVFPVITPEKK-------------SRVTNFTTDIQKRNLVHSSFDPCDFDVILPGMLIKTYLKLSIDGSLEGKFHGFPVCVQPIH---HKITDQISTELTMCVIGIDLSLKQLDCSLLSHLKPPFKGSTDLL-DVCIGYSEKNCTVTKRDKTKIVISIPDKKYVTGFIAKGHIDPK-----LQKTDIGSNVIVRYLDYNLIDNVIHATTLNSLLAQSYFSIHQAKLGEIIKGKVLSFSKHGFTVKISSNLTGLIPIPHLSDKPMSNAQKLLAPGDQVQCRVFHIDLLENRLLLTIKKSLMTSTLPIISGISDLQTGMILCGFVAKIFDFGLVVIMFNNVKGWVPIGRVPESKRKSLRVAYYVGKPVEVKVIRWEVATNKIELSLKEESTIDEEVIEKNPVN--------DLEIGDIYEAVITKARVDGFNVRLCPSNKVAFLPFIHLSDSREHRKLFEAHYRMSEKDQLKXXXXXXXXXXXXXXXSKKKSLIEAAVKNEVVKSNNSLTINSQWIGWVIKNESFGLLVELPSGVKGLVRNKDISDILPLSGQSRDLFEIGDTVMAKIIELDPLNLNRILFTLKMSSTYRASEHLVKSINFLIHHFEERKFLKSTVSCK-----NVSKLNLGDLVEVKITKQCEWGYTLTLNNDDSVTGFIRNEHLPNSPITETSVRNAIIIDIDLKDQAIEVTMVNSYVNALSHRR-NDCTRIEVDQNIASDVLGFNKDFVVSIFQGHAGGNLVFIPTKRFWNDIAKESMWLVKQRNNTILKTVLENEVFIGSLEINEPIN 2753
++LG +KEI E++L+++LP+ G I +IS+ Y KL+ + + D ++ L+ LF+ GQ++ K K + K+ +L++ P E+N ++ A+ LK G+ + ++ S+ED GY+L+ GI G+ +FL + + GK + P + K +R T +++ N D +LPGML+ + + + KF + + H + Q E+ ++ I + K + S+L HLK + S DLL G + V DKTK V + +K VT F ++ K Q GS R LD++ +DN++ + S+L Q + G +++ V K G +VK+S+ + G +P HL D + +K +++CRV ++D + RL+LT K+SL+ S LPII+ S L+TG+ + GF+ KI D G++V ++NNVKG+VP + K +Y+G+ V+ +V+ +E +T+ +V E+ P D EIG + + ITK GF+V L PS AF+P HLSD E+ ++ Y SE + +K + ++ + ++KK S ++AA + ++ + + G + K +G+ V+ + + GL K +SD S L+++G +V+AK+IE+D R L +L+MS Y + I+ L + ER + S + K +S++ +G +V V + + E G L + + G + E++ A+++ ID+ +E+ V A+ H+R N ++++ Q++ DVL DF++ +GHA G L ++P K+ ND ++ + + Q N+ ++K + + + + SL+ +E N
Sbjct: 80 LILGCVKEIQEYELVLNLPNGLKGFVPITSISDTYTKLLQQMVASNDGEKEEDIPSLHDLFTVGQVLCCKCVELVGGKKAGKKRLKLTINPGEVNKSLQASGLKGGMVIPCSVSSKEDHGYVLDVGIKGVQAFLGNKDAAKG---LGKGCVLHPGQHLKCKVKGSSSLGLMSGDTRTIQVTISLKELNDAVVP-DGSTLQNLLPGMLVNAKISKLYESGIGVKFLTYSGIINKSHLMKDPQSFQKQEEVRGTILYIHPTTKSISLSMLPHLKE-VQPSNDLLASFSPGSVIEKAEVLSVDKTKGVY-LRLEKNVTAFAPLKNLSDKEIKDIAQVFRAGSTHRCRVLDHDYMDNIMLVSCKESVLNQKFLGYQDIHPGMVVECNVQGIHKKGVSVKVSNQIRGFVPTIHLFDAALKQPEKKFKESQKMKCRVLNVDPAKQRLILTHKRSLVNSKLPIITQYSQLETGITVDGFIVKIMDAGVLVALYNNVKGFVPKKELSAEKIDYPEKMFYIGQVVKCRVLNC--------FPDEERATLSFKVSERTPFGSKLATVPEDFEIGKLVDCKITKKTDSGFDVALLPSRLRAFIPKAHLSDHMENCEVLWDSY--SEGNVIK--SAMYFNRSSVLTLTKKPSFVQAAKDDNLITEFSKIKPGLLLPGVIHKVMDYGVFVDTCNALIGLAPTKFMSDKRVADASS--LYKVGQSVIAKVIEVDE-EKKRFLLSLRMSDCYHDDTSI--GIDHLEDYLVERDLVLSKLEGKKGQKHRLSEVAVGSVVGVTVAEVTEHGALCNL--ESGLRGVVTYENMIGVTCQPGDHLEAVVLHIDVLASCLELAFNQELVKAIKHKRENKFSQVKPGQHMKCDVLLIKDDFILVSLKGHALGKLGYLPAKKHPNDFLEKHQFSINQTNSVVVKRIYMDHILL-SLQTHEEKN 993 HSP 2 Score: 76.6406 bits (187), Expect = 5.661e-10 Identity = 58/219 (26.48%), Postives = 100/219 (45.66%), Query Frame = 3
Query: 3729 KRRETGESLKNPTTETEFELLIFNHPHDSNAWIKFMNFYLENDKNIDKARSIAERAMKMLLSNDIENRFQLMKKYMLLEIDELVAKKDDVSYDDQLIR-FRELCQRAMTQKAKQMYIHVCKNLINAKLFDLAEELSKRFIKDFPNDSVSWFHLFLIRFSQKKYLVVRETLVNAQRSLSVADFRDLTIRVAQAEIEQGDVSRGVQSLVDIFQNRPKDISL 4382
+ R G+ ++ P + E++ L+ S W+ +M F L+ + IDKAR++AERA+K + + + + + YM LE + +QL + F Q+A K Q I + + ++ +LAE+L + +K F +W F Q + R+ L + +SL D +L + AQ E + G+ RG +I N PK L
Sbjct: 1524 EERMLGQQME-PQSIEEYDRLVLQSSDSSVVWLAYMAFLLKTTE-IDKARAVAERALKTISFREEQEKLNVWVAYMNLE--------NMYGSPEQLNQVFERALQQAEPFKVYQKLIDI---YVRSEKHELAEQLYNKLVKRFSLRKDTWISFGTFYFRQNRAESARKLLQRSLKSLEKKDHIELIAKFAQMEFQHGEAERGKTMFENILSNYPKRTDL 1729
BLAST of Programmed cell death 11 vs. TrEMBL
Match: A0A1S8X515 (S1 RNA binding domain protein OS=Opisthorchis viverrini OX=6198 GN=X801_02300 PE=4 SV=1) HSP 1 Score: 306.22 bits (783), Expect = 1.550e-80 Identity = 266/1034 (25.73%), Postives = 472/1034 (45.65%), Query Frame = 3
Query: 48 MENDSILLGRIKEIHEFKLIISLPHNKSGVCRIANISEEYNKLINEFNEDKSIMNEVARLNQLFSKGQIVQ---------VKLTKNSSNKKN--ELSMIPSEINCNINANRLKQGIKLQVAIKSREDKGYILETGIGGINSFLPFTECSNAEYKTGKMLEVFPVIT------PEKKSRVTNFTTDIQ-KRNLVHSSFDPCDFDVILPGMLIKTYLKLSIDGSLEGKFHGFPVCVQPIHHKITD---QISTELTMCVIGIDLSLKQLDCSLLSHLKPP-FKGSTDLLDVC----IGYSEKNCTVTKRDKTKIVISIPDKKYVTGFIAKGHIDPKLQKTDI------GSNVIVRYLDYNLIDNVIHATTLNSLLAQSYFSIHQAKLGEIIKGKVLSFSKHGFTVKISSNLTGLIPIPHLSDKPMSNAQKLLAPGDQVQCRVFHIDLLENRLLLTIKKSLMTSTLPIIS----------GISDLQTGMILCGFVAKIFDFGLVVIMFNNVKGWVP---IGRVPESKRKSLRVAYYVGKPVEVKVIRW---------------EVATNKIELSLKEESTIDEEVIE-KNPVNDLEIGDIYEAVITKARVDGFNVRLCPSNKVA-------------FLPFIHLSDSREHRKLFEAHY-RMSEKDQLKXXXXXXXX------XXXXXXXSKKKSLIEAAVKNEVVKSN-----------------NSLTINSQWIGWVIKNESFGLLVELPSGVKGLVRNKDISDI-LPLSGQSRDLFEIGDTVMAKIIELDPLNLNRILFTLKMSSTYRASEHLV----KSINFLIHHFE---ERKFLKSTVSCKNVSKLNLGDLVEVKITKQCEWGYTLTLNNDDSVTGFIRNEHLPNSPITETS-VRNA-------------IIIDIDLKDQAIEVTMVNSYVNALSHRRNDCTRI-EVDQNIASDVLGF-NKDFVVSIFQGHAGGNLVFIPTKRFWNDIAKESMWLVKQRNNTILKTVLENE-----VFIGSLEINEPINCDDAQ 2768
M+ + ++LGRIK + +F L + LPH + G I +IS Y+ L+ + + I + V L LF GQ+V+ V+ ++ S + K+ ELS+ P +N I ++ + ++ + ED GY + TGI G++ FLP + + Y G ++ +PV++ RV TT + +LV P F + PG ++ + + +L KF + + + H++ ++ +I E+ +C+I +D KQL SLL HL P F ++ +C IG N + + DK I +S+P + + + + + KL ++ G V R +D++L+++V AT LL + SI + G++I V F+K G V+ L GLIP HL+D P+ + G ++ CRV +D N+L+LT K+ L+ ++ P++ G+ D QT + FV KI + GL++ ++ W+P G PE L Y+ G+ + V+++ + +K +SLK + + + K ++ + +G ++ A + K + G +V L P++ + FL F HLSD + LF R+ L + ++ VIVS + SL+ AA +++ +S+ N L + +QW WV+ + +G+ V+ PSG++GL + ++D +P LF G TV+AK++EL R L TL+M TY A EH V +S+ I E R+ L +S +GDL+E Q E T+ ++ S ++ + + PI + + NA ++ ID + +EV + VN++ +R+N+ + Q ++S + F ++ V+ +GHA G +P +R +ND+ + W V QRN+ L+ + +E V + +L I +PI A+
Sbjct: 1 MQTEDLVLGRIKTVAKFYLDVCLPHGEIGRVNIYDISSSYSALVKKMVDSGEIDDSVTALEDLFHTGQLVRCYVKKAVPSVQSSQASDHSKHLSELSLFPELVNKGITRKHIRARTHISGSVDTEEDHGYTIGTGIQGLSCFLPKSLTTEKVY-LGSVMTFYPVVSDNITFLTSDTMRVLRVTTQLDNPSDLVLDPAAPVHFGCLTPGTWLRATVHKKVGSTLVAKFSDYLISINRAHYRGSEDEYRIGMEVLVCLILVDPGTKQLTGSLLPHLLPSSFLHTSSCTTICKQLPIGMRLGNAVIERVDKRTIHLSVPGSETLQAVVRRAQLPTKLAVENLKSKFAPGQKVTCRVIDHDLLEDVAIATMKKKLLQLPFLSIEELSPGDLISAVVNRFTKTGVVVRAEDRLNGLIPYLHLADIPLKRPAEKFQRGQKIDCRVLTLDKGANKLILTAKRGLVDASCPLLGSKEMFDWVQRGVKD-QT--LFAAFVVKISERGLLLSGLGELRAWLPRRETGLAPED---VLEATYFRGQVLRVRIVHALNDSSQDGGKETSEPNRSRSKFLVSLKLKGKNEPSTKQRKTQLSSVYVGQVFNAKVRKVQNTGLHVDLFPTDNTSKDPSMWSGSVGSGFLAFDHLSDFESNCALFAQFMTRLKPGAVLDLDRSGPRSVVVINKASSTVIVSARPSLLRAASNHQLAESDAENKNVVDIHTGFVSDFNDLRVGTQWFAWVVNHVDYGIFVQFPSGIRGLAPVRLLTDTRIPKHVALTSLFPTGATVIAKVVELASSEKRRCLVTLRMLDTYFAEEHYVDIAIRSLESCIMELEWLSRRQHL--------LSSFRIGDLIEF----QAEALDTIIVSGQVS---RLKADKVGKHPIPAIAYLANADGIECVPGKTYAGVVSFIDPTAERLEVALSTWLVNSVRNRKNNAASTPRLGQKVSSITIAFRSRTIAVAALRGHASGCFGILPARRTFNDVLGGNAWAVGQRNDVTLRQIFSDEGTTPSVHLCTLAIYDPITNPPAR 1012 HSP 2 Score: 65.855 bits (159), Expect = 9.878e-7 Identity = 56/249 (22.49%), Postives = 100/249 (40.16%), Query Frame = 3
Query: 3762 PTTETEFELLIFNHPHDSNAWIKFMNFYLENDK--NIDKARSIAERAMKMLLSN-------DIENRFQLMKKYMLLEIDEL---VAKKDDVS----------YDDQLIRFRELCQRAMTQKAKQMYIHVCKNLINAKLFDLAEELSKRFIKDFPNDSVSWFHLFLIRFSQKKYLVVRETLVNAQRSLSVADFRDLTIRVAQAEIEQGDVSRGVQSLVDIFQNRPKDISLKNRIVSILENNGLSEHVSKI 4442
PTT E+EL + N P ++ W +M L + + +AR+IAER ++ + S+ + +L+ Y+++E EL + +++ ++ +Q R ++ R + L + F+ AE+L++R IK P + W L +RF + RE NA L A+ E E GD R + + PK + + +L G S+ I
Sbjct: 1554 PTTTEEYELAVRNAPSNATCWTAYMKHVLSGSELHCLTEARAIAERGLRAITSSAGLEPGEQDTQQARLLSFYLVMEAKELERCIQQQEQMTSLTGSDPVLETSEQASRLSQVLSRLVNLDQSSFTRRAIDILADIGQFERAEDLARRLIKSSPGEVDRWLSLVKVRFRAGRVAAAREAQRNAVNILRSVHLPRFLTCSARLEFEFGDADRAIGLFREQLVAHPKQKIVYEEFIKLLLLAGKSKEARSI 1802
BLAST of Programmed cell death 11 vs. Ensembl Cavefish
Match: pdcd11 (programmed cell death 11 [Source:ZFIN;Acc:ZDB-GENE-030131-4076]) HSP 1 Score: 255.758 bits (652), Expect = 1.950e-68 Identity = 225/844 (26.66%), Postives = 411/844 (48.70%), Query Frame = 3
Query: 60 SILLGRIKEIHEFKLIISLPHNKSGVCRIANISEEYNKLINEFNEDKSIMNEVARLNQLFSKGQIVQVKLTKNSSNKKN----ELSMIPSEINCNINANRLKQGIKLQVAIKSREDKGYILETGIGGINSFLPFTECSNAEYKTGKMLEVFPVITPEKKSRVTNFTTDIQKRNLVHSSFDP---CDFDVILPGMLIKTYLKLSIDGSLEGKFHGFPVCVQPIHHKITD------------QISTELTMCVIGIDLSLKQLDCSLLSHLKPPFKGSTDLLD----VCIGYSEKNCTVTK-RDKTKIVISIPDKKYVTGFIAKGHIDPKLQKTDIGSNVIV-------RYLDYNLIDNVIHATTLNSLLAQSYFSIHQAKLGEIIKGKVLSFSKHGFTVKISSNLTGLIPIPHLSDKPMSNAQKLLAPGDQVQCRVFHIDLLENRLLLTIKKSLMTSTLPIISGISDLQTGMILCGFVAKIFDFGLVVIMFNNVKGWVPIGRVPESKRKSLRVAYYVGKPVEVKVIRWEVATNKIELSLKEESTIDEEVIEKNPVNDLEIGDIYEAVITKARVDGFNVRLCPSNKVAFLPFIHLSDSREHRKLFEAHYRMSEKDQLKXXXXXXXXXXXXXXXSKKKSLIEAAVKNEVVKSNNSLTINSQWIGWVIKNESFGLLVELPSGVKGLVRNKDISD-ILPLSGQSRDLFEIGDTVMAKIIELDPLNLNRILFTLKMSSTYRASEHLVKSINFLIHHFEERKFLKSTVSCKN-----VSKLNLGDLVEVKITKQCEWGYTLTLNNDD----SVTGFIRNEHLPNSPITETSVRNAIIIDIDLKDQAIEVTMV 2468
+ +LG +KEI +F++++ LP G I++I + YN+L+ + N D E ++L GQ+V+ ++ ++K+ ++S+ P E+N +++++ LK G+ L ++S ED GY+++ G+ G +FLP + G+ + V V + RV + + +K + + P +LPG+L++ +K + HG V + + D + E+ V+ + S + + SL SHL PP D+L+ V +G C +T + ++ +PD F+ K + K + N ++ R DY+ ++ IH TL ++ +YFS K+G++I+ VLS K+G VKIS ++ ++P HL+D ++N +K ++QCRV +D+ +++LT KKSL+ S LP+++ SD + G+I G + I DFG +V + +VKG VP + + + +YVG+ V+ KV+R +V K+ LS + + D E + D E+G + EAV+ K + G +V + P A LP I LSD + L + ++ L +VV ++ + + +SKK L+ A K +VVKS + L + +GWV +G+ V P + GL + ISD +P + LF++G TV+AK+ LD +R L +LK S + E ++ L ER+ + ++ +S + LGD +++ + E G ++ L +D +V + + +P + +V +++ +DL I V+++
Sbjct: 40 TAMLGCVKEISDFEIVVGLPSGLRGFLPISSICDSYNELLTK-NLDSGNDLETVSSSELLVPGQLVRCVVSSLGTSKQGFACIKVSINPKEVNKDLSSSSLKAGMTLGACVESIEDHGYLIDIGVAGTKAFLP-------KLNVGRYMTVL-VTEVKNGGRVVRVSVNPEK--VSQACAGPQHGWTLSNLLPGLLVQARIK-------KVTLHGLIVTFLSSYTGVVDFMHIDPDKASKYSVGDEVKARVVYTEPSTRHVSLSLRSHLLPP---EGDVLNAASIVQVGTVIDGCKMTAVHYHSGAIMELPDGN--VAFVHKYQM--KESSEEYNPNRLLAEPKHNLRITDYSPLEQ-IHIATLR-IIKTTYFSHQDIKVGQLIECTVLSVEKYGVHVKISDHIKAMVPKVHLADVTLTNPEKKFKVDMRIQCRVLSVDVANRKIILTRKKSLIESPLPVLALYSDARVGLITHGVIVCIKDFGCIVRFYGDVKGLVPKTEMTTDSSANPQSLFYVGQVVKAKVLRCDVELEKLVLSFRAVTQADVEAVNSAKF-DFEVGKV-EAVVLKKDLTGLHVSILPDEVPALLPMIQLSDHSTNWPLL---WDGLQEGDLISNVVCLSKNKQGITLSKKPMLLAALSKGDVVKSFSELQVGMIMVGWVKDIMPYGVFVHFPHNLFGLAPSAAISDKFIP---GTEGLFQVGQTVLAKVTNLDE-EKHRFLVSLKESEVIFSKE---EAQARLFQGQSERRAAYEMKTNRDALLEELSTVTLGDKLKLTVGDTTEDG-SVNLTSDQFKNVTVQASAHHAEVNATPGCKVTV---VVLHVDLLASQIHVSLL 840
BLAST of Programmed cell death 11 vs. Ensembl Cavefish
Match: pdcd11 (programmed cell death 11 [Source:ZFIN;Acc:ZDB-GENE-030131-4076]) HSP 1 Score: 247.284 bits (630), Expect = 1.749e-67 Identity = 224/845 (26.51%), Postives = 405/845 (47.93%), Query Frame = 3
Query: 60 SILLGRIKEIHEFKLIISLPHNKSGVCRIANISEEYNKLINEFNEDKSIMNEVARLNQLFSKGQIVQVKLTKNSSNKKN----ELSMIPSEINCNINANRLKQGIKLQVAIKSREDKGYILETGIGGINSFLPFTECSNA----EYKTGKMLEVFPVITPEKKSRVTNFTTDIQKRNLVHSSFDP---CDFDVILPGMLIKTYLKLSIDGSLEGKFHGFPVCVQPIHHKITD------------QISTELTMCVIGIDLSLKQLDCSLLSHLKPPFKGSTDLLD----VCIGYSEKNCTVTK-RDKTKIVISIPDKKYVTGFIAKGHI-------DPKLQKTDIGSNVIVRYLDYNLIDNVIHATTLNSLLAQSYFSIHQAKLGEIIKGKVLSFSKHGFTVKISSNLTGLIPIPHLSDKPMSNAQKLLAPGDQVQCRVFHIDLLENRLLLTIKKSLMTSTLPIISGISDLQTGMILCGFVAKIFDFGLVVIMFNNVKGWVPIGRVPESKRKSLRVAYYVGKPVEVKVIRWEVATNKIELSLKEESTIDEEVIEKNPVNDLEIGDIYEAVITKARVDGFNVRLCPSNKVAFLPFIHLSDSREHRKLFEAHYRMSEKDQLKXXXXXXXXXXXXXXXSKKKSLIEAAVKNEVVKSNNSLTINSQWIGWVIKNESFGLLVELPSGVKGLVRNKDISD-ILPLSGQSRDLFEIGDTVMAKIIELDPLNLNRILFTLKMSSTYRASEHLVKSINFLIHHFEERKFLKSTVSCKN-----VSKLNLGDLVEVKITKQCEWG-YTLTLNNDDSVTGFIRNEHLPNSPITETSVRNAIIIDIDLKDQAIEVTMV 2468
+ +LG +KEI +F++++ LP G I++I + YN+L+ + N D E ++L GQ+V+ ++ ++K+ ++S+ P E+N +++++ LK G+ L ++S ED GY+++ G+ G +FLP + + A + G+ + V V + RV + + +K + + P +LPG+L++ +K + HG V + + D + E+ V+ + S + + SL SHL PP D+L+ V +G C +T + ++ +PD F+ K + +P + N+ R DY+ ++ + AT S++ +YFS K+G++I+ VLS K+G VKIS ++ ++P HL+D ++N +K +V R+ +D+ +++LT KKSL+ S LP+++ SD + G+I G + I DFG +V + +VKG VP + + + +YVG+ V+ KV+R +V K+ LS + + D E + D E+G EAV+ K + G +V + P A LP I LSD + L + ++ L +VV ++ + + +SKK L+ A K +VVKS + L + +GWV +G+ V P + GL + ISD +P + LF++G TV+AK+ LD +R L +LK S + E ++ L ER+ + ++ +S + LGD +++ + E G LT + +VT H T +++ +DL I V+++
Sbjct: 43 TAMLGCVKEISDFEIVVGLPSGLRGFLPISSICDSYNELLTK-NLDSGNDLETVSSSELLVPGQLVRCVVSSLGTSKQGFACIKVSINPKEVNKDLSSSSLKAGMTLGACVESIEDHGYLIDIGVAGTKAFLPKDKENEAKSPKDLNVGRYMTVL-VTEVKNGGRVVRVSVNPEK--VSQACAGPQHGWTLSNLLPGLLVQARIK-------KVTLHGLIVTFLSSYTGVVDFMHIDPDKASKYSVGDEVKARVVYTEPSTRHVSLSLRSHLLPP---EGDVLNAASIVQVGTVIDGCKMTAVHYHSGAIMELPDGN--VAFVHKYQMKESSEEYNPNRLLAEPKHNL--RITDYSPLEQIHIATLRKSIIKTTYFSHQDIKVGQLIECTVLSVEKYGVHVKISDHIKAMVPKVHLADVTLTNPEKKF----KVDMRI-QLDVANRKIILTRKKSLIESPLPVLALYSDARVGLITHGVIVCIKDFGCIVRFYGDVKGLVPKTEMTTDSSANPQSLFYVGQVVKAKVLRCDVELEKLVLSFRAVTQADVEAVNSAKF-DFEVGKKVEAVVLKKDLTGLHVSILPDEVPALLPMIQLSDHSTNWPLL---WDGLQEGDLISNVVCLSKNKQGITLSKKPMLLAALSKGDVVKSFSELQVGMIMVGWVKDIMPYGVFVHFPHNLFGLAPSAAISDKFIP---GTEGLFQVGQTVLAKVTNLDE-EKHRFLVSLKESEVIFSKE---EAQARLFQGQSERRAAYEMKTNRDALLEELSTVTLGDKLKLTVGDTTEDGSVNLTSDQFKNVTVQASAHHAEGVNATPGCKVTVVVLHVDLLASQIHVSLL 853
BLAST of Programmed cell death 11 vs. Ensembl Sea Lamprey
Match: pdcd11 (programmed cell death 11 [Source:ZFIN;Acc:ZDB-GENE-030131-4076]) HSP 1 Score: 166.007 bits (419), Expect = 2.371e-41 Identity = 176/748 (23.53%), Postives = 347/748 (46.39%), Query Frame = 3
Query: 6 KIHVLKIFKLN*LIMENDSILLGRIKEIHEFKLIISLPHNKSGVCRIANISEEYNKLINEFNEDKSIMNE-VARLNQLFSKGQIVQVKLTKNSSNKKN----ELSMIPSEINCNINANRLKQGIKLQVAIKSREDKGYILETGIGGINSFLPFTECSNA--EYKTGKMLEVF-PVITPEKKSRVTNFTTDIQK-----RNLVHSSFDPCDFDVILPGMLIK-TYLKLSIDGSLEGKFHG-FPVCVQPIH--HKITDQISTELTMCVIGIDLSLKQLDCSLLSHLKPPFKGSTDLLDVCIGYSEKNCTVTK-RDKTKIVISIPDKKYVTGFIAKGHI-DPKLQKTDIGSNVIVRYLDYNLIDNVIHATTLNSLLAQSYFSIHQAKLGEIIKGKVLSFSKHGFTVKISSNLTGLIPIPHLSDKPMSNAQKLLAPGDQVQCRVFHIDLLENRLLLTIKKSLMTSTLPIISGISDLQTGMILCGFVAKIFDFGLVVIMFNNVKGWVPIGRVPESKRKSLRV--------AYYVGKPVEVKVIRWEVATNKIELSLKEESTIDEEVIEKNPVND----LEIGDIYEAVITKARVDGFNVRLCPSNKVAFLPFIHLSDSRE-HRKLFEAHYRMSEKDQLKXXXXXXXXXXXXXXXSKKKSLIEAAVKNEVVKSNNSLTINSQWIGWVIKNESFGLLVELPSGVKGLVRNKDISDILPLSGQSRDLFEIGDTVMAKIIELDPLNLNRILFTLKMS 2153
K+ + I KL ++ D ++LG +K + +L + LP +G +I ++ + Y K + + N D ++ +E V L++L+ G +V ++ + K N LS+ P ++N +++A+ L+ G+ L + S ED GY+++ G+ G +FL + K G+ L V PV + R + + + + D +LPG+++ T ++ DG L +F G F V +H ++ + ++ +CV+ + S K + S L L P K ++D + +G ++C +++ I++ +P+ F+ I D + Q S R + ++ +D A+ S++ + +LG+ ++G VL+ K G V+++ + G +P+ HL+D + + +K +PG++V C+V + +++L+LT K++L+ S L + GM+ G V + DFG +V + NVK ++R L + A+Y G+ V+ V+ A ++ +SL + E PV +E+G + + G +V + S F+P +HLSD+ R L E + D L + N ++++KK +L A V K+ + L +G + +G+ VE P ++G+ +SD +S + + + +G TV+A + +D +R+ +L++S
Sbjct: 78 KVQFIDILKLK--MVNPDMLVLGCVKVSLDHELEVGLPGCLTGNVQIVHVCDAYTKSLGD-NLDSNLESETVTPLSELYPPGTLVPCRVMEVVQGKGNWCRINLSVNPRDVNKDLSASSLRPGMLLHGCVASVEDHGYMVDIGVYGTQAFLSKAKAQALVNSKKAGQNLSVGQPVWCIVETVRSQGHSVQLSANPTKLSAAIANEKHGWTLDNLLPGVILSGTVERVEHDG-LVVEFLGLFEGSVDSLHLSPQVIYKKGQKVKVCVLHVMPSSKLIGLSTLPALLQPGKPASDPIGFTVGDVFEDCAISRILTGAGILLVLPNGS--PAFVHVKQISDKERQFLSEDSKHKCRVIAFSHVDQAAIASLRQSVIEGPFMRYSDLELGQTVEGTVLTVDKFGLQVRLTDYVRGFVPLSHLADVAVLHPEKKFSPGNEVTCKVLNCCAEKHKLMLTHKRALVRSKLRPLVSFESAVPGMVAHGTVVCVRDFGCIVRFYGNVKAL--------ARRSDLGLDFGADPTQAFYTGQVVKAVVLNSSPAEERMLVSLSGTMSGRETQDAGCPVQQTSFAIEVGKCVDVQVRCKSEKGLDVNVTGSGAPGFMPMMHLSDNVHVCRLLLEV---VEPGDVLS--ATCFSERNGKILLTKKHALQVALSGGNVAKTLDDLQAGMLLVGVTRRMLPYGVSVEFPYALRGMAFKAALSDEYVVSCE--EFYSVGQTVLAAVTRVDE-EKSRLDISLRVS 803 HSP 2 Score: 71.633 bits (174), Expect = 1.552e-12 Identity = 52/229 (22.71%), Postives = 107/229 (46.72%), Query Frame = 3
Query: 3762 PTTETEFELLIFNHPHDSNAWIKFMNFYLENDKNIDKARSIAERAMKMLLSNDIENRFQLMKKYMLLEIDELVAKKDDVSYDDQLIRFRELCQRAMTQKAKQMYIHVCKNLINAKLFDLAEELSKRFIKDFPNDSVSW--FHLFLIRFSQKKYLVVRETLVNAQRSLSVADFRDLTIRVAQAEIEQGDVSRGVQSLVDIFQNRPKDISLKNRIVSILENNGLSEHVSKI 4442
P + +F+ L + P+ S W+++M F+L+ + +D+AR++AERA+K +S E + +L LL ++ L Y D+ R + A + + H+ + I + F A+ L + ++ F + W + FL++ Q R + A +SL + D+ ++ AQ + G+V GV + + PK + + + +L +G ++ + +
Sbjct: 1607 PQSVDDFDRLALSSPNSSLVWLQYMAFHLQATE-VDRARAVAERALKT-ISFSREEQEKLNVWVALLNLENL--------YGDEASLMRAFERAVQHNDALKAFRHLAQIYIGSDKFQQADVLYNKMLRRFRQEKAVWLAYGSFLVQRGQTD--SARRLMQRALKSLPEREHVDVIVKFAQLDFRSGEVEHGVAVFENTLSSYPKRTDIWSIYIDMLAKHGTAQQIRAV 1823
BLAST of Programmed cell death 11 vs. Ensembl Yeast
Match: RRP5 (RNA binding protein involved in synthesis of 18S and 5.8S rRNAs; component of ribosomal small subunit (SSU) processome and 90S preribosome; required for pre-rRNA packaging and compaction of processome into dense terminal balls; part of Mak21p-Noc2p-Rrp5p module that associates with nascent pre-rRNA during transcription with role in biogenesis of large ribosomal subunit; binds single stranded tracts of U's; relocalizes from nucleolus to nucleus upon DNA replication stress [Source:SGD;Acc:S000004842]) HSP 1 Score: 97.0561 bits (240), Expect = 1.437e-20 Identity = 135/590 (22.88%), Postives = 248/590 (42.03%), Query Frame = 3
Query: 48 MENDSILLGRIKEIHEFKLIISLPHNKSGVCRIANISEEYNKLINEFNED-----------KSIM------------------NEVARLNQLFSKGQIVQVKLTKNSS---------NKKNELSMIPSEINCNINANRLKQGIKLQVAIKSREDKGYILETGIGGINSFLPFTECSNAEYKTGKML--EVFPVITPEKKSRVTNFTTDIQ-KRNLVHSSFDPCDFDVILPGMLIKTYLKLSIDGSLEGKFHGFPVCVQPIHHKITDQISTELTMCVIGIDLSLKQLDC------------SLLSH---LKPPFKGSTDLLDVCIGYSEKNCTVTKRDKTKIVISIPDKKYVTGFIAKGHIDPKLQKTDIGSNVIVRYLDYNLIDNVIHATTLNSLLAQSYFSIHQAKLGEIIKG-KVLSFSKHGFTVKI-SSNLTGLIPIPHLSDKPMSNAQKLLAPGDQVQCRVFHIDLLENRLLLTIKKSLMT---STLPIISGISDL----QTGMILCGFVAKIFDFGLVVIMFNNVKGWVPIGRVPESKRKSLRVAYYVGKPVEVKVI------RWEVATNKI--ELSLKEESTID 1598
++N S LLG+I I + L I+ SG + +ISEE+ ++ + +ED KS + NE+ L + F GQ ++ + KN+S K+ EL++ PS +N + + +K +Q A+KS ED G L+ G+ G F+ + N E K+L VF +K R TD K+N + D I+PG ++ + + GK G V + H T VIG + + + C S L H L+ + + L IGY+ ++C++ RD + +++ D + + K H ++ + + N+ R L Y+ +D++ +T L Y + +GE++ ++ S S G +KI + +P H+SD + ++ G +V+ RV ++ N + +T+KKSL+ + LP++S + + + G ++ F + G++P + E K +G+ V VK++ R +AT K+ E + +++ TI+
Sbjct: 116 LKNGSSLLGQISAITKQDLCITFTDGISGYVNLTHISEEFTSILEDLDEDMDSDTDAADEKKSKVEDAEYESSDDEDEKLDKSNELPNLRRYFHIGQWLRCSVIKNTSLEPSTKKSKKKRIELTIEPSSVNIYADEDLVK-STSIQCAVKSIEDHGATLDVGLPGFTGFIAKKDFGNFE----KLLPGAVFLGNITKKSDRSIVVNTDFSDKKNKITQ---ISSIDAIIPGQIVDLLCESITKNGIAGKVFGLVSGVVNVSHLRTFSEEDLKHKFVIGSSIRCRIIACLENKSGDKVLILSNLPHILKLEDALRSTEGLDAFPIGYTFESCSIKGRDSEYLYLALDDDR-----LGKVH-SSRVGEIENSENLSSRVLGYSPVDDIYQLSTDPKYLKLKYLRTNDIPIGELLPSCEITSVSSSGIELKIFNGQFKASVPPLHISDTRLVYPERKFKIGSKVKGRVISVNSRGN-VHVTLKKSLVNIEDNELPLVSTYENAKNIKEKNEKTLATIQVFKPNGCIISFFGGLSGFLPNSEISEVFVKRPEEHLRLGQTVIVKLLDVDADRRRIIATCKVSNEQAAQQKDTIE 690 HSP 2 Score: 69.707 bits (169), Expect = 3.508e-12 Identity = 47/163 (28.83%), Postives = 81/163 (49.69%), Query Frame = 3
Query: 1098 KLGEIIKGKVLSFSKHGFTVKISSNLTGLIPIPHLSDKPMSNAQKLLAPGDQVQCRVFHIDLLENRLLLTIKKSLMTSTLPIISGISDLQTGMILCGFVAKIFDFGLVVIMFN--NVKGWVPIGRVPESKRKSLRVAYYVGKPVEVKVIRWEVATNKIELSLK 1580
K GEI+ G V + + G V +S + +P+ LSD + +K P V +V D ++R+ LT+++S + L ++ SD++ G + G + + DFG+ V + N NV G I + + K + L + VG V+ V++ +I LSLK
Sbjct: 1175 KQGEIVDGIVKNVNDKGIFVYLSRKVEAFVPVSKLSDSYLKEWKKFYKPMQYVLGKVVTCDE-DSRISLTLRESEINGDLKVLKTYSDIKAGDVFEGTIKSVTDFGVFVKLDNTVNVTGLAHITEIADKKPEDLSALFGVGDRVKAIVLKTNPEKKQISLSLK 1336 HSP 3 Score: 56.9954 bits (136), Expect = 2.601e-8 Identity = 61/217 (28.11%), Postives = 100/217 (46.08%), Query Frame = 3
Query: 3762 PTTETEFELLIFNHPHDSNAWIKFMNFYLENDKNIDKARSIAERAMKMLLSNDIENRFQLMKKYMLLEIDELVAKKDDVSYDDQLIRFRELCQR--AMTQKAKQMYIHVCKNLINAKLFDLAEELSKRFIKDFPNDSVS-WFHL--FLIRFSQKKYLVVRETLVNAQRSLSVADFRDLTIRVAQAEIEQGDVSRGVQSLVDIFQNRPKDISLKNRIV 4397
P + +FE L+ +P+ S W+ +M F L+ + I+KAR +AERA+K + N E +L +L ++ ++ + F CQ + T K + I+ ++ FD A EL K K F + VS W FLI ++++ R L NA ++L + ++ + AQ E +GD RG + + PK I L N V
Sbjct: 1458 PESVADFERLLIGNPNSSVVWMNYMAFQLQLSE-IEKARELAERALKTI--NFREEAEKLNIWIAMLNLENTFGTEETLEE-----VFSRACQYMDSYTIHTKLLGIYEI-----SEKFDKAAELFKATAKKFGGEKVSIWVSWGDFLISHNEEQE--ARTILGNALKALPKRNHIEVVRKFAQLEFAKGDPERGRSLFEGLVADAPKRIDLWNVYV 1659 HSP 4 Score: 48.521 bits (114), Expect = 8.795e-6 Identity = 72/266 (27.07%), Postives = 109/266 (40.98%), Query Frame = 3
Query: 984 IGSNVIVRYLDYNLIDNVIHAT--TLNSLLAQSYFSIHQAKLGE-IIKGKVLSFSKHGFTVKISS-NLTGLIPIPHLSDKPMSN--AQ-KLLAPGDQVQCRVFHIDLLENRLLLTIKKSLMT----STLPII-SGISDLQTGMILCGFVAKIFDFGLVVIMFNNVKGWVPIGRVPESKRKSLRVAYYVGKPVEVKVIRWEVATNKIELSLKE--------------ESTIDEEVIEKNPVNDLEIGDIYEAVITKARVDGFNVRLC 1703
+G VIV+ LD + I AT N AQ +I G II V+ +K V+I L G+I + HLSD + AQ K L G ++ V D +++K SL+ TLP+ + DL + + ++ I D GL V G V +S+ + A+Y+ + V V ++R + K LSLK E +D + +DL IG I +A I + + NV L
Sbjct: 653 LGQTVIVKLLDVDADRRRIIATCKVSNEQAAQQKDTIENIVPGRTIITVHVIEKTKDSVIVEIPDVGLRGVIYVGHLSDSRIEQNRAQLKKLRIGTELTGLVIDKDTRTRVFNMSLKSSLIKDAKKETLPLTYDDVKDLNKDVPMHAYIKSISDKGLFVAFNGKFIGLVLPSYAVDSRDIDISKAFYINQSVTVYLLRTDDKNQKFLLSLKAPKVKEEKKKVESNIEDPVDSSI---KSWDDLSIGSIVKAKIKSVKKNQLNVILA 915
BLAST of Programmed cell death 11 vs. Ensembl Nematostella
Match: EDO38955 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SBJ3]) HSP 1 Score: 179.489 bits (454), Expect = 3.282e-45 Identity = 186/734 (25.34%), Postives = 330/734 (44.96%), Query Frame = 3
Query: 66 LLGRIKEIHEFKLIISLPHNKSGVCRIANISEEYNKLINEFNEDKSIMNEVARLNQLFSKGQ----IVQVKLTKNSSNKKNELSMIPSEINCNINANRLKQGIKLQVAIKSREDKGYILETGIGGINSFLPFTECSNAEYKTGKML----EVFPVITPEKKSRVTNFTTDIQK-RNLVHSSFDPCDFDVILPGMLIKTYLKLSIDGSL--------EGKFH--------GFPVCVQPIHHKITDQISTELTMCVIGIDLSLKQLDCSLLSHLKPPFKGSTDLLDVCIGYSEKNCTVTKRDKT-KIVISIPDKKYVTGFIAKGHIDPKL-----QKTDIGSNVIVRYLDYNLIDNVIHATTLNSLLAQSYFSIHQAKLGEIIKGKVLSFSKHGFTVKISSNLTGLIPIPHLSDKPMSNAQKLLAPGDQVQCRVFHIDLLENRLLLTIKKSLMTSTLPIISGISDLQTGMILCGFVAKIFDFGLVVIMFNNVKGWVPIGRVPESKRKSLRVAYYVGKPVEVKVIRWEVATNKIELSLKEES---------------TIDEEVIEKNPV---NDLEIGDIYEAVITKARVDGFNVRLCPS----NKVAFLPFIHLSDSREH-----------------RKLFEAHYRMSEKDQLKXXXXXXXXXXXXXXXSKKKSLI-EAAVKNEVVKSNNSLTINSQWIGWVIKNESFGLLVELPSGVKGLVRNKDISDILPLSGQ 2054
LLG +KE+ EF+LIISLP+ SG I +I+E+ + + + ++ I + + L LF+ +V+ L+ ++K +LS+ P ++N + + G L + S ED GY+L GI G FL ++ KTG++L + ++ RV + D K ++ + SS F +LPGML+ T + + EG H G ++ ++ K + ++ L + +SL LD S++ P F+ + IG N T+T+ D+ ++ ++ D + GF+ + K +K G++ R L N ID ++ TT S++ + + K G I++G +++ K G V +S ++ GL+ HL+D + + +K L G V+CRV +D + RL LT KK++++STL +I+ SD + G GF+ + ++G +V +NNVKG VP ++ + + R +Y+G+ + VI K++LSLK S ++ K V +D++ G + + G V P +F+ +SD+ H R+ F + S+ + I+S++K ++ E A K E VK+ SL + S G V K + G+ + LP G+KG V ++ + L G+
Sbjct: 118 LLGAVKEVGEFELIISLPNGLSGFVHILDINEKLMSALAKSSTEERIEDSIPSLGDLFTVNSLVVCVVKELLSSKHGHRKVKLSLRPEDVNAGVT--NIVPGFVLPGCVSSVEDHGYVLSFGIPGKTGFL-------SKKKTGRVLVEGQYLNTIVESADTGRVIRVSVDQDKIKSAMISSDMKVRFSSLLPGMLVNTRVSQCTSSGVIVSFLELFEGSVHILHLPENGGSGENLEKLYKKKSKHVARILYVNPKNKVVSLSMLD-SIIQFKLPSFESCS------IGDIFDNVTITRGDQGLGLLANVKDG--LNGFVHFSQVSDKQIEKLGKKYKAGTSHKCRVLGMNTIDGLLSLTTKKSIINKPFMRYEDIKPGSIVEGTIITLEKFGMLVSVSDHIKGLVTNMHLADIILKHPEKKLTEGKVVKCRVLTVDPGQRRLHLTHKKTMVSSTLQVITQYSDAKPGTTSHGFITSVREYGCLVTFYNNVKGLVPKDQLGIQESEDPRGVFYLGQVLTCHVISCNPDQQKLKLSLKANSANKSSTQVSLQTASTSLKNAAESKTMVTNFSDIKPGMVLPGFVKLLMGYGVFVEFAPGILGLAPNSFIANHFVSDAASHFKIGQTLVAQVNEVDAERQRFLVSLKQSDLNPGSDWTSATAGALLEEILSERKHILDELASKTEDVKNLLSLPVGSCIEGKVSKVKKNGISLTLPDGLKGFVFHQLAQGVSCLEGE 833 HSP 2 Score: 98.9821 bits (245), Expect = 1.068e-20 Identity = 133/589 (22.58%), Postives = 246/589 (41.77%), Query Frame = 3
Query: 990 SNVIVRYLDYNLIDNVIHATTLNSLLAQSYFSIHQAKLGEIIKGKVLSFSKHGFTV--KISSNLTGLIPIPHLSDKPMSNAQKLLAPGDQVQCRVFHIDLLENRLLLTIKKSLMTSTLPIISGISDLQTGMILCGFVAKIFDFGLVVIMFNNVKGWVPIGRVPESKRKSLRVAYYVGKPVEVKVIRWEVATNKIELSLKE---ESTIDEEVIEKNPVNDLEIGDIYEAVITKARVDGF------NVR-LCPSNKVAFLPFIHLSDSREHRKLF------EAHYRMSEKDQLK-----XXXXXXXXXXXXXXXSKKKSLIEAAVKNEVVKSNNSLTINSQWIGWVIKNESFGLLVELPSGVKGLVRNKDISDILPLSGQSRDLFEIGDTVMAKIIELDPLNLNRILFTLKMSSTYRASEHLVKSINFLIHH-FEERKFL-----KSTVSCKNVSKLNLGDLVEVKITKQCEWGYTLTLNNDDSVTGFIRNEHLPNSPITETSVRNAIIIDIDLKDQAIEVTMVNSYVNALSHRRNDCTRIEVDQNIASDVLGFNKDFVVSIFQGH--------AGGNLVFIPTKRFWNDI 2645
S + R L N + V+ + L+S++ S +G+I ++ G + + L G + +SDK + K G +CRV ++ ++ L LT KKS++ P + D++ G I+ G + + FG++V + +++KG V + + K GK V+ +V+ + ++ L+ K+ ST+ +VI + +D + G IT R G NV+ L P +++ + +S + R +F H DQ K + + + SL AA +V + + + G+V +G+ VE G+ GL N I++ S F+IG T++A++ E+D R L +LK S S+ + L+ ERK + T KN+ L +G +E K++K + G +LTL D + GF+ ++ E V ++D+D+K +E+T++ V +++N +++ Q + DF+V + + A + + P K NDI
Sbjct: 351 SKHVARILYVNPKNKVVSLSMLDSIIQFKLPSFESCSIGDIFDNVTITRGDQGLGLLANVKDGLNGFVHFSQVSDKQIEKLGKKYKAGTSHKCRVLGMNTIDGLLSLTTKKSIINK--PFMR-YEDIKPGSIVEGTIITLEKFGMLVSVSDHIKGLVTNMHLADIILKHPEKKLTEGKVVKCRVLTVDPGQRRLHLTHKKTMVSSTL--QVITQ--YSDAKPGTTSHGFITSVREYGCLVTFYNNVKGLVPKDQLG------IQESEDPRGVFYLGQVLTCHVISCNPDQQKLKLSLKANSANKSSTQVSLQTASTSLKNAAESKTMVTNFSDIKPGMVLPGFVKLLMGYGVFVEFAPGILGLAPNSFIANHFVSDAASH--FKIGQTLVAQVNEVDA-ERQRFLVSLKQSDLNPGSDWTSATAGALLEEILSERKHILDELASKTEDVKNLLSLPVGSCIEGKVSKVKKNGISLTL--PDGLKGFVFHQLAQGVSCLEGEVVQGCVLDLDVKKSVVELTLLPDVVKGRQNQKNKPKQMKPGQPV---------DFIVQLIKAEYMVVVLPCAAFKIGYAPAKMHLNDI 912 HSP 3 Score: 72.0182 bits (175), Expect = 2.218e-12 Identity = 60/255 (23.53%), Postives = 113/255 (44.31%), Query Frame = 3
Query: 3681 RKLTNVKKEILIRTAEKRRETGESLKNPTTETEFELLIFNHPHDSNAWIKFMNFYLENDKNIDKARSIAERAMKMLLSNDIENRFQLMKKYMLLEIDELVAKKDDVSYDDQLIRFRELCQRAMTQ-KAKQMYIHVCKNLINAKLFDLAEELSKRFIKDFPNDSVSWFHLFLIRFSQKKYLVVRETLVNAQRSLSVADFRDLTIRVAQAEIEQGDVSRGVQSLVDIFQNRPKDISLKNRIVSILENNGLSEHVSKI 4442
R +++ L RT + +T + P +F+ L+ + P++S W+++M F+L + IDKAR++AERA++ + E R +L L+ ++ L + + LI+ E RA+ + K+++ H+ ++ +LAE+L K F W K R+ L +SL + ++ A E + GD RG L + N PK + + + ++ G + V +I
Sbjct: 1480 RAAKKAEEDFLYRTEQALLDTDHT---PECAEDFDRLVLSSPNNSVTWLQYMAFHLHTTE-IDKARAVAERALRTISFR--EEREKLNIWVALMNLENLYGTQ------ESLIKVFE---RALQHNEPKKVFFHLITIYTQSEKTELAEKLFHTMTKRFSQSKKVWIEFGRFFMKTGKPDSARKLLQRGLKSLPTRKHVETIVQFALMEFKNGDPQRGQTVLESVLSNYPKRTDIWSVYIDMMSKQGHPDTVRQI 1719
BLAST of Programmed cell death 11 vs. Ensembl Nematostella
Match: EDO29780 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T2N3]) HSP 1 Score: 71.2478 bits (173), Expect = 2.055e-14 Identity = 41/124 (33.06%), Postives = 69/124 (55.65%), Query Frame = 3
Query: 1110 IIKGKVLSFSKHGFTVKISSNLTGLIPIPHLSDKPMSNAQKLLAPGDQVQCR--------VFHIDLLENRLLLTIKKSLMTSTLPIISGISDLQTGMILCGFVAKIFDFGLVVIMFNNVKGWVP 1457
I++G +++ K G V +S ++ GL+ HL+D + + +K L G V R V +D + RL LT KK++++S L +I+ SD + G GF+ + ++G +V +NNVKG VP
Sbjct: 7 ILQGTIITLEKFGMLVSVSDHIKGLVTNMHLADIILKHPEKKLTEGKVVNKRLINPFTLQVLTVDPGQRRLHLTHKKTMVSSILQVITQYSDAKPGTTSHGFITSVREYGCLVTFYNNVKGLVP 130
BLAST of Programmed cell death 11 vs. Ensembl Nematostella
Match: EDO29782 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T2N5]) HSP 1 Score: 66.6254 bits (161), Expect = 1.283e-11 Identity = 54/229 (23.58%), Postives = 103/229 (44.98%), Query Frame = 3
Query: 3759 NPTTETEFELLIFNHPHDSNAWIKFMNFYLENDKNIDKARSIAERAMKMLLSNDIENRFQLMKKYMLLEIDELVAKKDDVSYDDQLIRFRELCQRAMTQ-KAKQMYIHVCKNLINAKLFDLAEELSKRFIKDFPNDSVSWFHLFLIRFSQKKYLVVRETLVNAQRSLSVADFRDLTIRVAQAEIEQGDVSRGVQSLVDIFQNRPKDISLKNRIVSILENNGLSEHVSKI 4442
P +F+ L+ + P++S W+++M F+L + IDKAR++AERA++ + E R +L L+ ++ L ++ LI+ + +RA+ + K+++ H+ ++ +LAE+L K F W K R+ L +SL + ++ A E + GD RG L + N PK + + + ++ G + V +I
Sbjct: 6 TPECAEDFDRLVLSSPNNSVTWLQYMAFHLHTTE-IDKARAVAERALRTISFR--EEREKLNIWVALMNLENLYGTQES------LIK---VFERALQHNEPKKVFFHLITIYTQSEKTELAEKLFHTMTKRFSQSKTVWIEFGRFFMKTGKPDSARKLLQRGLKSLPTRKHVETIVQFALMEFKNGDPQRGQTVLESVLSNYPKRTDIWSVYIDMMSKQGHPDTVRQI 222
BLAST of Programmed cell death 11 vs. Ensembl Medaka
Match: pdcd11 (programmed cell death 11 [Source:ZFIN;Acc:ZDB-GENE-030131-4076]) HSP 1 Score: 240.736 bits (613), Expect = 3.351e-65 Identity = 213/800 (26.62%), Postives = 372/800 (46.50%), Query Frame = 3
Query: 63 ILLGRIKEIHEFKLIISLPHNKSGVCRIANISEEYNKLINEFNEDKSIMNEVARLNQLFSKGQIV-----QVKLTKNSSNKKNELSMIPSEINCNINANRLKQGIKLQVAIKSREDKGYILETGIGGINSFLPFTECSNAEYKTGKMLEVFPVITPEK---KSRVTNFTTDIQKRNLVHSSFDP---CDFDVILPGMLIK-TYLKLSIDGSLEGKFHGFPVCVQPIHHKITDQIST-----ELTMCVIGIDLSLKQLDCSLLSHLKPPFKG--STDLLDVCIGYSEKNCTVTK-RDKTKIVISIPDKKYVTGFIAKGHIDPKLQKTD-----IGSNVIVRYLDYNLIDNVIHATTLNSLLAQSYFSIHQAKLGEIIKGKVLSFSKHGFTVKISSNLTGLIPIPHLSDKPMSNAQKLLAPGDQVQCRVFHIDLLENRLLLTIKKSLMTSTLPIISGISDLQTGMILCGFVAKIFDFGLVVIMFNNVKGWVPIGRVPESKRKSLRVAYYVGKPVEVKVIRWEVATNKIELSLKEESTIDEEVIEKNPVNDLEIGDIYEAVITKARVDGFNVRLCPSNKVAFLPFIHLSDSREHRKLFEAHYRMSEKDQLKXXXXXXXXXXXXXXXSKKKSLIEAAVKNEVVKSNNSLTINSQWIGWVIKNESFGLLVELPSGVKGLVRNKDISDILPLSGQSRDLFEIGDTVMAKIIELDPLNLNRILFTLKMSSTYRASEHLVKSINFLIHHFEERKFLKSTVSCKNV---SKLNLGDLVEVKITKQCEWGYTLTLNNDDSVTGFIRNEHL 2378
++LG +K + +F++ + LP G I NI + Y KL+++ E E+ L LF G ++ Q+ +TK S +LS+ P +N ++ ++ LK G+ L ++S ED G I++ G+ G +FLP + + +L + E+ RV + + + + + +P +LPG+L+K T K++ G L F V +H + + ST ++ CV+ ++ S + + SL HL P G + IG K C + K+ V+ +PD F+ + H+ + T+ R LD++ ++ + AT S++ + ++ K G++++G V HG V +S ++ GL+P HLSD + N +K APG +V+CRV +D +L LT KK+L+ S LP+ SD + G + G+V I DFG +V +N+VKG VP+ + +YVG+ ++ V++ + +K+ LS K + V D ++G EA + K V+G V + P A LP +HLSD + L + ++ + V N N N+ ++KK ++ + V K+ + LT+ Q +GWV +G+ VE P G+ GL +SD + F++G TV AK+ LD R L TLK+S + LI+ +ERK +K +S + V + L++G+ + + + + G + S T +H+
Sbjct: 72 LMLGCVKTVADFEVSVGLPCGLQGFLSIKNICDSYTKLLSDQLESDD--AEICSLPHLFHPGMVLRCVVAQLDVTKGGS-LSIQLSINPKLVNKSVTSSSLKAGMVLSGCVESVEDHGCIIDIGVNGTKAFLPEEAMKTEQNQLRGVLGQYLTCLVERVKNDGRVVSLS--VNPAAVAQACAEPRQGWSLSNLLPGLLVKSTVKKVTKHGLLLDFLSSFSGQVDFLHME-PEPTSTYTEGLQVQACVLYVEPSSRLVGLSLRRHLLQPSSGIEPSPAEGDRIGEVLKGCKLAAMHHKSGAVLELPDGS--PAFVHRNHLKEPNEPTNENRVYAAPEHTCRILDFSPMEQIHFATLRKSVIEKPFYRYQDLKAGQVVEGTVSVLLSHGMVVHLSDHIKGLVPRTHLSDIVLKNPEKKYAPGMKVKCRVLSVDPEGKKLYLTRKKALVESPLPLFLTYSDARPGRVSHGYVVCIKDFGCIVRFYNDVKGLVPLSELSSEPVVHPEDVFYVGQVLKAAVLQCDPERSKMILSFKAAVEGGAAEATEAHV-DCDVGKRLEAKVVKKSVNGLEVAILPDEIRAILPTMHLSDHVSNCPLL---WESLQEGDVISDAVCFNRINLNITLTKKPAVRRILEEGAVAKNFSELTVGMQLVGWVKNIMPYGVFVEFPYGLLGLAPKSAMSD--KFISDATAAFQLGQTVFAKVTNLDE-EKRRFLVTLKISEVICPEGDVYTR---LINGLQERKAVKEMMSSRGVLILAALSVGERLMLTVDSVKDSGAIFKSDRLTSATVLASKQHM 853
BLAST of Programmed cell death 11 vs. Planmine SMEST
Match: SMESG000005637.1 (SMESG000005637.1) HSP 1 Score: 2750.7 bits (7129), Expect = 0.000e+0 Identity = 1467/1470 (99.80%), Postives = 1469/1470 (99.93%), Query Frame = 3
Query: 48 MENDSILLGRIKEIHEFKLIISLPHNKSGVCRIANISEEYNKLINEFNEDKSIMNEVARLNQLFSKGQIVQVKLTKNSSNKKNELSMIPSEINCNINANRLKQGIKLQVAIKSREDKGYILETGIGGINSFLPFTECSNAEYKTGKMLEVFPVITPEKKSRVTNFTTDIQKRNLVHSSFDPCDFDVILPGMLIKTYLKLSIDGSLEGKFHGFPVCVQPIHHKITDQISTELTMCVIGIDLSLKQLDCSLLSHLKPPFKGSTDLLDVCIGYSEKNCTVTKRDKTKIVISIPDKKYVTGFIAKGHIDPKLQKTDIGSNVIVRYLDYNLIDNVIHATTLNSLLAQSYFSIHQAKLGEIIKGKVLSFSKHGFTVKISSNLTGLIPIPHLSDKPMSNAQKLLAPGDQVQCRVFHIDLLENRLLLTIKKSLMTSTLPIISGISDLQTGMILCGFVAKIFDFGLVVIMFNNVKGWVPIGRVPESKRKSLRVAYYVGKPVEVKVIRWEVATNKIELSLKEESTIDEEVIEKNPVNDLEIGDIYEAVITKARVDGFNVRLCPSNKVAFLPFIHLSDSREHRKLFEAHYRMSEKDQLKXXXXXXXXXXXXXXXSKKKSLIEAAVKNEVVKSNNSLTINSQWIGWVIKNESFGLLVELPSGVKGLVRNKDISDILPLSGQSRDLFEIGDTVMAKIIELDPLNLNRILFTLKMSSTYRASEHLVKSINFLIHHFEERKFLKSTVSCKNVSKLNLGDLVEVKITKQCEWGYTLTLNNDDSVTGFIRNEHLPNSPITETSVRNAIIIDIDLKDQAIEVTMVNSYVNALSHRRNDCTRIEVDQNIASDVLGFNKDFVVSIFQGHAGGNLVFIPTKRFWNDIAKESMWLVKQRNNTILKTVLENEVFIGSLEINEPINCDDAQVVNIDIPFKNLARKIKAIKDKTYRTYFHSVSKTKVYFYISKLQRGCCKLLNYSTSIEEIQQLIEKTPQRYSIMNKSVKITDAKKGHGIASGHFLEKDVLEVGDTVCCKVTAIISKNKYILKMPFDNIGXXXXXXXXXXXXXXXXNNSIVQCRIEEIAKKGSKNLYYLSLNGLKELKDKDQXXXXXXXXXXXXXXXXXXXXXXXQTNETPIEESIENSANQDMECXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXIPIVVTSKDKVMENLSSLYKRIHQXXXXXXXXXXXXXXXXXXPTPAKVRKLTNVKKEILIRTAEKRRETGESLKNPTTETEFELLIFNHPHDSNAWIKFMNFYLENDKNIDKARSIAERAMKMLLSNDIENRFQLMKKYMLLEIDELVAKKDDVSYDDQLIRFRELCQRAMTQKAKQMYIHVCKNLINAKLFDLAEELSKRFIKDFPNDSVSWFHLFLIRFSQKKYLVVRETLVNAQRSLSVADFRDLTIRVAQAEIEQGDVSRGVQSLVDIFQNRPKDISLKNRIVSILENNGLSEHVSKIAAVSN 4457
MENDSILLGRIKEIHEFKLIISLPHNKSGVCRIANISEEYNKLINEFNEDKSIMNEVARLNQLFSKGQIVQVKLTKNSSNKKNELSMIPSEINCNINANRLKQGIKLQVAIKSREDKGYILETGIGGINSFLPFTECSNAEYKTGKMLEVFPVITPEKKSRVTNFTTDIQKRNLVHSSFDPCDFDVILPGMLIKTYLKLSIDGSLEGKFHGFPVCVQPIHHKITDQISTELTMCVIGIDLSLKQLDCSLLSHLKPPFKGSTDLLDVCIGYSEKNCTVTKRDKTKIVISIPDKKYVTGFIAKGHIDPKLQKTDIGSNVIVRYLDYNLIDNVIHATTLNSLLAQSYFSIHQAKLGEIIKGKVLSFSKHGFTVKISSNLTGLIPIPHLSDKPMSNAQKLLAPGDQVQCRVFHIDLLENRLLLTIKKSLMTSTLPIISGISDLQTGMILCGFVAKIFDFGLVVIMFNNVKGWVPIGRVPESKRKSLRVAYYVGKPVEVKVIRWEVATNKIELSLKEESTIDEEVIEKNPVNDLEIGDIYEAVITKARVDGFNVRLCPSNKVAFLPFIHLSDSREHRKLFEAHYRMSEKDQLKISVVVINVHNTNVIVSKKKSLIEAAVKNEVVKSNNSLTINSQWIGWVIKNESFGLLVELPSGVKGLVRNKDISDILPLSGQSRDLFEIGDTVMAKIIELDPLNLNRILFTLKMSSTYRASEHLVKSINFLIHHFEERKFLKSTVSCKNVSKLNLGDLVEVKITKQCEWGYTLTLNNDDSVTGFIRNEHLPNSPITETSVRNAIIIDIDLKDQAIEVTMVNSYVNALSHRRNDCTRIEVDQNIASDVLGFNKDFVVSIFQGHAGGNLVFIPTKRFWNDIAKESMWLVKQRNNTILKTVLENEVFIGSLEINEPINCDDAQVVNIDIPFKNLARKIKAIKDKTYRTYFHSVSKTKVYFYISKLQRGCCKLLNYSTSIEEIQQLIEKTPQRYSIMNKSVKITDAKKGHGIASGHFLEKDVLEVGDT+CCKVTAIISKNKYILKMPFDNIGKLYAKKLKKY+PFYPKNNSIVQCRIEEIAKKGSKNLYYLSLNGLKELKDKDQKENEIKDENSEIEEEHKKEAMKEQ NETPIEESIENSANQDMECEEQDDESESKVESDDGNESSNDSQDDSDSDVDIPIVVTSKDKVMENLSSLYKRIHQSDDEEKENDEENEEVKSEPTPAKVRKLTNVKKEILIRTAEKRRETGESLKNPTTETEFELLIFNHPHDSNAWIKFMNFYLENDKNIDKARSIAERAMKMLLSNDIENRFQLMKKYMLLEIDELVAKKDDVSYDDQLIRFRELCQRAMTQKAKQMYIHVCKNLINAKLFDLAEELSKRFIKDFPNDSVSWFHLFLIRFSQKKYLVVRETLVNAQRSLSVADFRDLTIRVAQAEIEQGDVSRGVQSLVDIFQNRPKDISLKNRIVSILENNGLSEHVSKIAAVSN
Sbjct: 1 MENDSILLGRIKEIHEFKLIISLPHNKSGVCRIANISEEYNKLINEFNEDKSIMNEVARLNQLFSKGQIVQVKLTKNSSNKKNELSMIPSEINCNINANRLKQGIKLQVAIKSREDKGYILETGIGGINSFLPFTECSNAEYKTGKMLEVFPVITPEKKSRVTNFTTDIQKRNLVHSSFDPCDFDVILPGMLIKTYLKLSIDGSLEGKFHGFPVCVQPIHHKITDQISTELTMCVIGIDLSLKQLDCSLLSHLKPPFKGSTDLLDVCIGYSEKNCTVTKRDKTKIVISIPDKKYVTGFIAKGHIDPKLQKTDIGSNVIVRYLDYNLIDNVIHATTLNSLLAQSYFSIHQAKLGEIIKGKVLSFSKHGFTVKISSNLTGLIPIPHLSDKPMSNAQKLLAPGDQVQCRVFHIDLLENRLLLTIKKSLMTSTLPIISGISDLQTGMILCGFVAKIFDFGLVVIMFNNVKGWVPIGRVPESKRKSLRVAYYVGKPVEVKVIRWEVATNKIELSLKEESTIDEEVIEKNPVNDLEIGDIYEAVITKARVDGFNVRLCPSNKVAFLPFIHLSDSREHRKLFEAHYRMSEKDQLKISVVVINVHNTNVIVSKKKSLIEAAVKNEVVKSNNSLTINSQWIGWVIKNESFGLLVELPSGVKGLVRNKDISDILPLSGQSRDLFEIGDTVMAKIIELDPLNLNRILFTLKMSSTYRASEHLVKSINFLIHHFEERKFLKSTVSCKNVSKLNLGDLVEVKITKQCEWGYTLTLNNDDSVTGFIRNEHLPNSPITETSVRNAIIIDIDLKDQAIEVTMVNSYVNALSHRRNDCTRIEVDQNIASDVLGFNKDFVVSIFQGHAGGNLVFIPTKRFWNDIAKESMWLVKQRNNTILKTVLENEVFIGSLEINEPINCDDAQVVNIDIPFKNLARKIKAIKDKTYRTYFHSVSKTKVYFYISKLQRGCCKLLNYSTSIEEIQQLIEKTPQRYSIMNKSVKITDAKKGHGIASGHFLEKDVLEVGDTICCKVTAIISKNKYILKMPFDNIGKLYAKKLKKYMPFYPKNNSIVQCRIEEIAKKGSKNLYYLSLNGLKELKDKDQKENEIKDENSEIEEEHKKEAMKEQINETPIEESIENSANQDMECEEQDDESESKVESDDGNESSNDSQDDSDSDVDIPIVVTSKDKVMENLSSLYKRIHQSDDEEKENDEENEEVKSEPTPAKVRKLTNVKKEILIRTAEKRRETGESLKNPTTETEFELLIFNHPHDSNAWIKFMNFYLENDKNIDKARSIAERAMKMLLSNDIENRFQLMKKYMLLEIDELVAKKDDVSYDDQLIRFRELCQRAMTQKAKQMYIHVCKNLINAKLFDLAEELSKRFIKDFPNDSVSWFHLFLIRFSQKKYLVVRETLVNAQRSLSVADFRDLTIRVAQAEIEQGDVSRGVQSLVDIFQNRPKDISLKNRIVSILENNGLSEHVSKIAAVSN 1470 The following BLAST results are available for this feature:
BLAST of Programmed cell death 11 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 2
BLAST of Programmed cell death 11 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 1
BLAST of Programmed cell death 11 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 1
BLAST of Programmed cell death 11 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 1
BLAST of Programmed cell death 11 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Programmed cell death 11 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 1
BLAST of Programmed cell death 11 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Programmed cell death 11 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Programmed cell death 11 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 2
BLAST of Programmed cell death 11 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 1
BLAST of Programmed cell death 11 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 1
BLAST of Programmed cell death 11 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 3
BLAST of Programmed cell death 11 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 1
BLAST of Programmed cell death 11 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 1
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30018697 ID=SMED30018697|Name=Programmed cell death 11|organism=Schmidtea mediterranea sexual|type=transcript|length=4553bpback to top protein sequence of SMED30018697-orf-1 >SMED30018697-orf-1 ID=SMED30018697-orf-1|Name=SMED30018697-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1471bp MENDSILLGRIKEIHEFKLIISLPHNKSGVCRIANISEEYNKLINEFNEDback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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